Sample records for magnetic fields magic

  1. NMR system and method having a permanent magnet providing a rotating magnetic field

    DOEpatents

    Schlueter, Ross D [Berkeley, CA; Budinger, Thomas F [Berkeley, CA

    2009-05-19

    Disclosed herein are systems and methods for generating a rotating magnetic field. The rotating magnetic field can be used to obtain rotating-field NMR spectra, such as magic angle spinning spectra, without having to physically rotate the sample. This result allows magic angle spinning NMR to be conducted on biological samples such as live animals, including humans.

  2. Method for high resolution magnetic resonance analysis using magic angle technique

    DOEpatents

    Wind, Robert A.; Hu, Jian Zhi

    2003-12-30

    A method of performing a magnetic resonance analysis of a biological object that includes placing the object in a main magnetic field (that has a static field direction) and in a radio frequency field; rotating the object at a frequency of less than about 100 Hz around an axis positioned at an angle of about 54.degree.44' relative to the main magnetic static field direction; pulsing the radio frequency to provide a sequence that includes a phase-corrected magic angle turning pulse segment; and collecting data generated by the pulsed radio frequency. The object may be reoriented about the magic angle axis between three predetermined positions that are related to each other by 120.degree.. The main magnetic field may be rotated mechanically or electronically. Methods for magnetic resonance imaging of the object are also described.

  3. Method for high resolution magnetic resonance analysis using magic angle technique

    DOEpatents

    Wind, Robert A.; Hu, Jian Zhi

    2004-12-28

    A method of performing a magnetic resonance analysis of a biological object that includes placing the object in a main magnetic field (that has a static field direction) and in a radio frequency field; rotating the object at a frequency of less than about 100 Hz around an axis positioned at an angle of about 54.degree.44' relative to the main magnetic static field direction; pulsing the radio frequency to provide a sequence that includes a phase-corrected magic angle turning pulse segment; and collecting data generated by the pulsed radio frequency. The object may be reoriented about the magic angle axis between three predetermined positions that are related to each other by 120.degree.. The main magnetic field may be rotated mechanically or electronically. Methods for magnetic resonance imaging of the object are also described.

  4. Magic-Angle-Spinning NMR Magnet Development: Field Analysis and Prototypes

    PubMed Central

    Voccio, John; Hahn, Seungyong; Park, Dong Keun; Ling, Jiayin; Kim, Youngjae; Bascuñán, Juan; Iwasa, Yukikazu

    2013-01-01

    We are currently working on a program to complete a 1.5 T/75 mm RT bore magic-angle-spinning nuclear magnetic resonance magnet. The magic-angle-spinning magnet comprises a z-axis 0.866-T solenoid and an x-axis 1.225-T dipole, each to be wound with NbTi wire and operated at 4.2 K in persistent mode. A combination of the fields creates a 1.5-T field pointed at 54.74 degrees (magic angle) from the rotation (z) axis. In the first year of this 3-year program, we have completed magnetic analysis and design of both coils. Also, using a winding machine of our own design and fabrication, we have wound several prototype dipole coils with NbTi wire. As part of this development, we have repeatedly made successful persistent NbTi-NbTi joints with this multifilamentary NbTi wire. PMID:24058275

  5. MAGIC: A Tool for Combining, Interpolating, and Processing Magnetograms

    NASA Technical Reports Server (NTRS)

    Allred, Joel

    2012-01-01

    Transients in the solar coronal magnetic field are ultimately the source of space weather. Models which seek to track the evolution of the coronal field require magnetogram images to be used as boundary conditions. These magnetograms are obtained by numerous instruments with different cadences and resolutions. A tool is required which allows modelers to fmd all available data and use them to craft accurate and physically consistent boundary conditions for their models. We have developed a software tool, MAGIC (MAGnetogram Interpolation and Composition), to perform exactly this function. MAGIC can manage the acquisition of magneto gram data, cast it into a source-independent format, and then perform the necessary spatial and temporal interpolation to provide magnetic field values as requested onto model-defined grids. MAGIC has the ability to patch magneto grams from different sources together providing a more complete picture of the Sun's field than is possible from single magneto grams. In doing this, care must be taken so as not to introduce nonphysical current densities along the seam between magnetograms. We have designed a method which minimizes these spurious current densities. MAGIC also includes a number of post-processing tools which can provide additional information to models. For example, MAGIC includes an interface to the DA VE4VM tool which derives surface flow velocities from the time evolution of surface magnetic field. MAGIC has been developed as an application of the KAMELEON data formatting toolkit which has been developed by the CCMC.

  6. Permanent magnet assembly producing a strong tilted homogeneous magnetic field: towards magic angle field spinning NMR and MRI.

    PubMed

    Sakellariou, Dimitris; Hugon, Cédric; Guiga, Angelo; Aubert, Guy; Cazaux, Sandrine; Hardy, Philippe

    2010-12-01

    We introduce a cylindrical permanent magnet design that generates a homogeneous and strong magnetic field having an arbitrary inclination with respect to the axis of the cylinder. The analytical theory of 3 D magnetostatics has been applied to this problem, and a hybrid magnet structure has been designed. This structure contains two magnets producing a longitudinal and transverse component for the magnetic field, whose amplitudes and homogeneities can be fully controlled by design. A simple prototype has been constructed using inexpensive small cube magnets, and its magnetic field has been mapped using Hall and NMR probe sensors. This magnet can, in principle, be used for magic angle field spinning NMR and MRI experiments allowing for metabolic chemical shift profiling in small living animals. Copyright © 2010 John Wiley & Sons, Ltd.

  7. Method for high resolution magnetic resonance analysis using magic angle technique

    DOEpatents

    Wind, Robert A.; Hu, Jian Zhi

    2003-11-25

    A method of performing a magnetic resonance analysis of a biological object that includes placing the biological object in a main magnetic field and in a radio frequency field, the main magnetic field having a static field direction; rotating the biological object at a rotational frequency of less than about 100 Hz around an axis positioned at an angle of about 54.degree.44' relative to the main magnetic static field direction; pulsing the radio frequency to provide a sequence that includes a magic angle turning pulse segment; and collecting data generated by the pulsed radio frequency. According to another embodiment, the radio frequency is pulsed to provide a sequence capable of producing a spectrum that is substantially free of spinning sideband peaks.

  8. Non-Fermi-liquid magic angle effects in high magnetic fields

    NASA Astrophysics Data System (ADS)

    Lebed, A. G.

    2016-07-01

    We investigate a theoretical problem of electron-electron interactions in an inclined magnetic field in a quasi-one-dimensional (Q1D) conductor. We show that they result in strong non-Fermi-liquid corrections to a specific heat, provided that the direction of the magnetic field is far from the so-called Lebed's magic angles (LMAs). If magnetic field is directed close to one of the LMAs, the specific heat corrections become small and the Fermi-liquid picture restores. As a result, we predict Fermi-liquid-non-Fermi-liquid angular crossovers in the vicinities of the LMA directions of the field. We suggest to perform the corresponding experiment in the Q1D conductor (Per) 2Au (mnt) 2 under pressure in magnetic fields of the order of H ≃25 T .

  9. Controlling soliton excitations in Heisenberg spin chains through the magic angle.

    PubMed

    Lu, Jing; Zhou, Lan; Kuang, Le-Man; Sun, C P

    2009-01-01

    We study the nonlinear dynamics of collective excitation in an N -site XXZ quantum spin chain, which is manipulated by an oblique magnetic field. We show that, when the tilted field is applied along the magic angle, theta_{0}=+/-arccossqrt[13] , the anisotropic Heisenberg spin chain becomes isotropic and thus an freely propagating spin wave is stimulated. Also, in the regime of tilted angles larger and smaller than the magic angle, two types of nonlinear excitations appear: bright and dark solitons.

  10. Solving the challenges of data preprocessing, uploading, archiving, retrieval, analysis and visualization for large heterogeneous paleo- and rock magnetic datasets

    NASA Astrophysics Data System (ADS)

    Minnett, R.; Koppers, A. A.; Tauxe, L.; Constable, C.; Jarboe, N. A.

    2011-12-01

    The Magnetics Information Consortium (MagIC) provides an archive for the wealth of rock- and paleomagnetic data and interpretations from studies on natural and synthetic samples. As with many fields, most peer-reviewed paleo- and rock magnetic publications only include high level results. However, access to the raw data from which these results were derived is critical for compilation studies and when updating results based on new interpretation and analysis methods. MagIC provides a detailed metadata model with places for everything from raw measurements to their interpretations. Prior to MagIC, these raw data were extremely cumbersome to collect because they mostly existed in a lab's proprietary format on investigator's personal computers or undigitized in field notebooks. MagIC has developed a suite of offline and online tools to enable the paleomagnetic, rock magnetic, and affiliated scientific communities to easily contribute both their previously published data and data supporting an article undergoing peer-review, to retrieve well-annotated published interpretations and raw data, and to analyze and visualize large collections of published data online. Here we present the technology we chose (including VBA in Excel spreadsheets, Python libraries, FastCGI JSON webservices, Oracle procedures, and jQuery user interfaces) and how we implemented it in order to serve the scientific community as seamlessly as possible. These tools are now in use in labs worldwide, have helped archive many valuable legacy studies and datasets, and routinely enable new contributions to the MagIC Database (http://earthref.org/MAGIC/).

  11. A permanent MRI magnet for magic angle imaging having its field parallel to the poles.

    PubMed

    McGinley, John V M; Ristic, Mihailo; Young, Ian R

    2016-10-01

    A novel design of open permanent magnet is presented, in which the magnetic field is oriented parallel to the planes of its poles. The paper describes the methods whereby such a magnet can be designed with a field homogeneity suitable for Magnetic Resonance Imaging (MRI). Its primary purpose is to take advantage of the Magic Angle effect in MRI of human extremities, particularly the knee joint, by being capable of rotating the direction of the main magnetic field B0 about two orthogonal axes around a stationary subject and achieve all possible angulations. The magnet comprises a parallel pair of identical profiled arrays of permanent magnets backed by a flat steel yoke such that access in lateral directions is practical. The paper describes the detailed optimization procedure from a target 150mm DSV to the achievement of a measured uniform field over a 130mm DSV. Actual performance data of the manufactured magnet, including shimming and a sample image, is presented. The overall magnet system mounting mechanism is presented, including two orthogonal axes of rotation of the magnet about its isocentre. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Methods for magnetic resonance analysis using magic angle technique

    DOEpatents

    Hu, Jian Zhi [Richland, WA; Wind, Robert A [Kennewick, WA; Minard, Kevin R [Kennewick, WA; Majors, Paul D [Kennewick, WA

    2011-11-22

    Methods of performing a magnetic resonance analysis of a biological object are disclosed that include placing the object in a main magnetic field (that has a static field direction) and in a radio frequency field; rotating the object at a frequency of less than about 100 Hz around an axis positioned at an angle of about 54.degree.44' relative to the main magnetic static field direction; pulsing the radio frequency to provide a sequence that includes a phase-corrected magic angle turning pulse segment; and collecting data generated by the pulsed radio frequency. In particular embodiments the method includes pulsing the radio frequency to provide at least two of a spatially selective read pulse, a spatially selective phase pulse, and a spatially selective storage pulse. Further disclosed methods provide pulse sequences that provide extended imaging capabilities, such as chemical shift imaging or multiple-voxel data acquisition.

  13. The Magnetics Information Consortium (MagIC)

    NASA Astrophysics Data System (ADS)

    Johnson, C.; Constable, C.; Tauxe, L.; Koppers, A.; Banerjee, S.; Jackson, M.; Solheid, P.

    2003-12-01

    The Magnetics Information Consortium (MagIC) is a multi-user facility to establish and maintain a state-of-the-art relational database and digital archive for rock and paleomagnetic data. The goal of MagIC is to make such data generally available and to provide an information technology infrastructure for these and other research-oriented databases run by the international community. As its name implies, MagIC will not be restricted to paleomagnetic or rock magnetic data only, although MagIC will focus on these kinds of information during its setup phase. MagIC will be hosted under EarthRef.org at http://earthref.org/MAGIC/ where two "integrated" web portals will be developed, one for paleomagnetism (currently functional as a prototype that can be explored via the http://earthref.org/databases/PMAG/ link) and one for rock magnetism. The MagIC database will store all measurements and their derived properties for studies of paleomagnetic directions (inclination, declination) and their intensities, and for rock magnetic experiments (hysteresis, remanence, susceptibility, anisotropy). Ultimately, this database will allow researchers to study "on the internet" and to download important data sets that display paleo-secular variations in the intensity of the Earth's magnetic field over geological time, or that display magnetic data in typical Zijderveld, hysteresis/FORC and various magnetization/remanence diagrams. The MagIC database is completely integrated in the EarthRef.org relational database structure and thus benefits significantly from already-existing common database components, such as the EarthRef Reference Database (ERR) and Address Book (ERAB). The ERR allows researchers to find complete sets of literature resources as used in GERM (Geochemical Earth Reference Model), REM (Reference Earth Model) and MagIC. The ERAB contains addresses for all contributors to the EarthRef.org databases, and also for those who participated in data collection, archiving and analysis in the magnetic studies. Integration with these existing components will guarantee direct traceability to the original sources of the MagIC data and metadata. The MagIC database design focuses around the general workflow that results in the determination of typical paleomagnetic and rock magnetic analyses. This ensures that individual data points can be traced between the actual measurements and their associated specimen, sample, site, rock formation and locality. This permits a distinction between original and derived data, where the actual measurements are performed at the specimen level, and data at the sample level and higher are then derived products in the database. These relations will also allow recalculation of derived properties, such as site means, when new data becomes available for a specific locality. Data contribution to the MagIC database is critical in achieving a useful research tool. We have developed a standard data and metadata template that can be used to provide all data at the same time as publication. Software tools are provided to facilitate easy population of these templates. The tools allow for the import/export of data files in a delimited text format, and they provide some advanced functionality to validate data and to check internal coherence of the data in the template. During and after publication these standardized MagIC templates will be stored in the ERR database of EarthRef.org from where they can be downloaded at all times. Finally, the contents of these template files will be automatically parsed into the online relational database.

  14. "Black Magic": Pepper in a Magnetic Field

    ERIC Educational Resources Information Center

    Peterson, John E.

    1977-01-01

    Describes a procedure to demonstrate the effect of a magnetic force on a moving charge. The materials used are inexpensive and with the use of an overhead projector, easily visible to an entire class. (CP)

  15. The Magnetics Information Consortium (MagIC) Online Database: Uploading, Searching and Visualizing Paleomagnetic and Rock Magnetic Data

    NASA Astrophysics Data System (ADS)

    Minnett, R.; Koppers, A.; Tauxe, L.; Constable, C.; Pisarevsky, S. A.; Jackson, M.; Solheid, P.; Banerjee, S.; Johnson, C.

    2006-12-01

    The Magnetics Information Consortium (MagIC) is commissioned to implement and maintain an online portal to a relational database populated by both rock and paleomagnetic data. The goal of MagIC is to archive all measurements and the derived properties for studies of paleomagnetic directions (inclination, declination) and intensities, and for rock magnetic experiments (hysteresis, remanence, susceptibility, anisotropy). MagIC is hosted under EarthRef.org at http://earthref.org/MAGIC/ and has two search nodes, one for paleomagnetism and one for rock magnetism. Both nodes provide query building based on location, reference, methods applied, material type and geological age, as well as a visual map interface to browse and select locations. The query result set is displayed in a digestible tabular format allowing the user to descend through hierarchical levels such as from locations to sites, samples, specimens, and measurements. At each stage, the result set can be saved and, if supported by the data, can be visualized by plotting global location maps, equal area plots, or typical Zijderveld, hysteresis, and various magnetization and remanence diagrams. User contributions to the MagIC database are critical to achieving a useful research tool. We have developed a standard data and metadata template (Version 2.1) that can be used to format and upload all data at the time of publication in Earth Science journals. Software tools are provided to facilitate population of these templates within Microsoft Excel. These tools allow for the import/export of text files and provide advanced functionality to manage and edit the data, and to perform various internal checks to maintain data integrity and prepare for uploading. The MagIC Contribution Wizard at http://earthref.org/MAGIC/upload.htm executes the upload and takes only a few minutes to process several thousand data records. The standardized MagIC template files are stored in the digital archives of EarthRef.org where they remain available for download by the public (in both text and Excel format). Finally, the contents of these template files are automatically parsed into the online relational database, making the data available for online searches in the paleomagnetic and rock magnetic search nodes. The MagIC database contains all data transferred from the IAGA paleomagnetic poles database (GPMDB), the lava flow paleosecular variation database (PSVRL), lake sediment database (SECVR) and the PINT database. Additionally, a substantial number of data compiled under the Time Averaged Field Investigations project is now included plus a significant fraction of the data collected at SIO and the IRM. Ongoing additions of legacy data include over 40 papers from studies on the Hawaiian Islands and Mexico, data compilations from archeomagnetic studies and updates to the lake sediment dataset.

  16. The Magnetics Information Consortium (MagIC) Online Database: Uploading, Searching and Visualizing Paleomagnetic and Rock Magnetic Data

    NASA Astrophysics Data System (ADS)

    Koppers, A.; Tauxe, L.; Constable, C.; Pisarevsky, S.; Jackson, M.; Solheid, P.; Banerjee, S.; Johnson, C.; Genevey, A.; Delaney, R.; Baker, P.; Sbarbori, E.

    2005-12-01

    The Magnetics Information Consortium (MagIC) operates an online relational database including both rock and paleomagnetic data. The goal of MagIC is to store all measurements and their derived properties for studies of paleomagnetic directions (inclination, declination) and their intensities, and for rock magnetic experiments (hysteresis, remanence, susceptibility, anisotropy). MagIC is hosted under EarthRef.org at http://earthref.org/MAGIC/ and has two search nodes, one for paleomagnetism and one for rock magnetism. These nodes provide basic search capabilities based on location, reference, methods applied, material type and geological age, while allowing the user to drill down from sites all the way to the measurements. At each stage, the data can be saved and, if the available data supports it, the data can be visualized by plotting equal area plots, VGP location maps or typical Zijderveld, hysteresis, FORC, and various magnetization and remanence diagrams. All plots are made in SVG (scalable vector graphics) and thus can be saved and easily read into the user's favorite graphics programs without loss of resolution. User contributions to the MagIC database are critical to achieve a useful research tool. We have developed a standard data and metadata template (version 1.6) that can be used to format and upload all data at the time of publication in Earth Science journals. Software tools are provided to facilitate easy population of these templates within Microsoft Excel. These tools allow for the import/export of text files and they provide advanced functionality to manage/edit the data, and to perform various internal checks to high grade the data and to make them ready for uploading. The uploading is all done online by using the MagIC Contribution Wizard at http://earthref.org/MAGIC/upload.htm that takes only a few minutes to process a contribution of approximately 5,000 data records. After uploading these standardized MagIC template files will be stored in the digital archives of EarthRef.org from where they can be downloaded at all times. Finally, the contents of these template files will be automatically parsed into the online relational database, making the data available for online searches in the paleomagnetic and rock magnetic search nodes. The MagIC database contains all data transferred from the IAGA paleomagnetic poles database (GPMDB), the lava flow paleosecular variation database (PSVRL), lake sediment database (SECVR) and the PINT database. In addition to that a substantial number of data compiled under the Time Averaged Field Investigations project is now included plus a significant fraction of the data collected at SIO and the IRM. Ongoing additions of legacy data include ~40 papers from studies on the Hawaiian Islands, data compilations from archeomagnetic studies and updates to the lake sediment dataset.

  17. Illuminating the Depths of the MagIC (Magnetics Information Consortium) Database

    NASA Astrophysics Data System (ADS)

    Koppers, A. A. P.; Minnett, R.; Jarboe, N.; Jonestrask, L.; Tauxe, L.; Constable, C.

    2015-12-01

    The Magnetics Information Consortium (http://earthref.org/MagIC/) is a grass-roots cyberinfrastructure effort envisioned by the paleo-, geo-, and rock magnetic scientific community. Its mission is to archive their wealth of peer-reviewed raw data and interpretations from magnetics studies on natural and synthetic samples. Many of these valuable data are legacy datasets that were never published in their entirety, some resided in other databases that are no longer maintained, and others were never digitized from the field notebooks and lab work. Due to the volume of data collected, most studies, modern and legacy, only publish the interpreted results and, occasionally, a subset of the raw data. MagIC is making an extraordinary effort to archive these data in a single data model, including the raw instrument measurements if possible. This facilitates the reproducibility of the interpretations, the re-interpretation of the raw data as the community introduces new techniques, and the compilation of heterogeneous datasets that are otherwise distributed across multiple formats and physical locations. MagIC has developed tools to assist the scientific community in many stages of their workflow. Contributors easily share studies (in a private mode if so desired) in the MagIC Database with colleagues and reviewers prior to publication, publish the data online after the study is peer reviewed, and visualize their data in the context of the rest of the contributions to the MagIC Database. From organizing their data in the MagIC Data Model with an online editable spreadsheet, to validating the integrity of the dataset with automated plots and statistics, MagIC is continually lowering the barriers to transforming dark data into transparent and reproducible datasets. Additionally, this web application generalizes to other databases in MagIC's umbrella website (EarthRef.org) so that the Geochemical Earth Reference Model (http://earthref.org/GERM/) portal, Seamount Biogeosciences Network (http://earthref.org/SBN/), EarthRef Digital Archive (http://earthref.org/ERDA/) and EarthRef Reference Database (http://earthref.org/ERR/) benefit from its development.

  18. Field-cycling NMR with high-resolution detection under magic-angle spinning: determination of field-window for nuclear hyperpolarization in a photosynthetic reaction center.

    PubMed

    Gräsing, Daniel; Bielytskyi, Pavlo; Céspedes-Camacho, Isaac F; Alia, A; Marquardsen, Thorsten; Engelke, Frank; Matysik, Jörg

    2017-09-21

    Several parameters in NMR depend on the magnetic field strength. Field-cycling NMR is an elegant way to explore the field dependence of these properties. The technique is well developed for solution state and in relaxometry. Here, a shuttle system with magic-angle spinning (MAS) detection is presented to allow for field-dependent studies on solids. The function of this system is demonstrated by exploring the magnetic field dependence of the solid-state photochemically induced nuclear polarization (photo-CIDNP) effect. The effect allows for strong nuclear spin-hyperpolarization in light-induced spin-correlated radical pairs (SCRPs) under solid-state conditions. To this end, 13 C MAS NMR is applied to a photosynthetic reaction center (RC) of the purple bacterium Rhodobacter (R.) sphaeroides wildtype (WT). For induction of the effect in the stray field of the magnet and its subsequent observation at 9.4 T under MAS NMR conditions, the sample is shuttled by the use of an aerodynamically driven sample transfer technique. In the RC, we observe the effect down to 0.25 T allowing to determine the window for the occurrence of the effect to be between about 0.2 and 20 T.

  19. A Simple Approach for Obtaining High Resolution, High Sensitivity ¹H NMR Metabolite Spectra of Biofluids with Limited Mass Supply

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hu, Jian Zhi; Rommereim, Donald N.; Wind, Robert A.

    2006-11-01

    A simple approach is reported that yields high resolution, high sensitivity ¹H NMR spectra of biofluids with limited mass supply. This is achieved by spinning a capillary sample tube containing a biofluid at the magic angle at a frequency of about 80Hz. A 2D pulse sequence called ¹H PASS is then used to produce a high-resolution ¹H NMR spectrum that is free from magnetic susceptibility induced line broadening. With this new approach a high resolution ¹H NMR spectrum of biofluids with a volume less than 1.0 µl can be easily achieved at a magnetic field strength as low as 7.05T.more » Furthermore, the methodology facilitates easy sample handling, i.e., the samples can be directly collected into inexpensive and disposable capillary tubes at the site of collection and subsequently used for NMR measurements. In addition, slow magic angle spinning improves magnetic field shimming and is especially suitable for high throughput investigations. In this paper first results are shown obtained in a magnetic field of 7.05T on urine samples collected from mice using a modified commercial NMR probe.« less

  20. (1)H-(13)C Hetero-nuclear dipole-dipole couplings of methyl groups in stationary and magic angle spinning solid-state NMR experiments of peptides and proteins.

    PubMed

    Wu, Chin H; Das, Bibhuti B; Opella, Stanley J

    2010-02-01

    (13)C NMR of isotopically labeled methyl groups has the potential to combine spectroscopic simplicity with ease of labeling for protein NMR studies. However, in most high resolution separated local field experiments, such as polarization inversion spin exchange at the magic angle (PISEMA), that are used to measure (1)H-(13)C hetero-nuclear dipolar couplings, the four-spin system of the methyl group presents complications. In this study, the properties of the (1)H-(13)C hetero-nuclear dipolar interactions of (13)C-labeled methyl groups are revealed through solid-state NMR experiments on a range of samples, including single crystals, stationary powders, and magic angle spinning of powders, of (13)C(3) labeled alanine alone and incorporated into a protein. The spectral simplifications resulting from proton detected local field (PDLF) experiments are shown to enhance resolution and simplify the interpretation of results on single crystals, magnetically aligned samples, and powders. The complementarity of stationary sample and magic angle spinning (MAS) measurements of dipolar couplings is demonstrated by applying polarization inversion spin exchange at the magic angle and magic angle spinning (PISEMAMAS) to unoriented samples. Copyright 2009 Elsevier Inc. All rights reserved.

  1. Investigation of Regional Influence of Magic-Angle Effect on T2 in Human Articular Cartilage with Osteoarthritis at 3 T

    PubMed Central

    Wang, Ligong; Regatte, Ravinder R.

    2014-01-01

    Rationale and Objectives The objectives of this research study were to determine the magic-angle effect on different subregions of in vivo human femoral cartilage through the quantitative assessment of the effect of static magnetic field orientation (B0) on transverse (T2) relaxation time at 3.0 T. Materials and Methods Healthy volunteers (n = 5l; mean age, 36.4 years) and clinical patients (n = 5; mean age, 64 years) with early osteoarthritis (OA) were scanned at 3.0-T magnetic resonance using an 8-channel phased-array knee coil (transmit-receive). Results The T2 maps revealed significantly greater values in ventral than in dorsal regions. When the cartilage regions were oriented at 55° to B0 (magic angle), the longest T2 values were detected in comparison with the neighboring regions oriented 90° and 180° (0°) to B0. The subregions oriented 180° (0°) to B0 showed the lowest T2 values. Conclusions The differences in T2 values of different subregions suggest that magic-angle effect needs to be considered when interpreting cartilage abnormalities in OA patients. PMID:25481517

  2. The MAGIC of CINEMA: first in-flight science results from a miniaturised anisotropic magnetoresistive magnetometer

    NASA Astrophysics Data System (ADS)

    Archer, M. O.; Horbury, T. S.; Brown, P.; Eastwood, J. P.; Oddy, T. M.; Whiteside, B. J.; Sample, J. G.

    2015-06-01

    We present the first in-flight results from a novel miniaturised anisotropic magnetoresistive space magnetometer, MAGIC (MAGnetometer from Imperial College), aboard the first CINEMA (CubeSat for Ions, Neutrals, Electrons and MAgnetic fields) spacecraft in low Earth orbit. An attitude-independent calibration technique is detailed using the International Geomagnetic Reference Field (IGRF), which is temperature dependent in the case of the outboard sensor. We show that the sensors accurately measure the expected absolute field to within 2% in attitude mode and 1% in science mode. Using a simple method we are able to estimate the spacecraft's attitude using the magnetometer only, thus characterising CINEMA's spin, precession and nutation. Finally, we show that the outboard sensor is capable of detecting transient physical signals with amplitudes of ~ 20-60 nT. These include field-aligned currents at the auroral oval, qualitatively similar to previous observations, which agree in location with measurements from the DMSP (Defense Meteorological Satellite Program) and POES (Polar-orbiting Operational Environmental Satellites) spacecraft. Thus, we demonstrate and discuss the potential science capabilities of the MAGIC instrument onboard a CubeSat platform.

  3. Double-quantum homonuclear rotary resonance: Efficient dipolar recovery in magic-angle spinning nuclear magnetic resonance

    NASA Astrophysics Data System (ADS)

    Nielsen, N. C.; Bildsøe, H.; Jakobsen, H. J.; Levitt, M. H.

    1994-08-01

    We describe an efficient method for the recovery of homonuclear dipole-dipole interactions in magic-angle spinning NMR. Double-quantum homonuclear rotary resonance (2Q-HORROR) is established by fulfilling the condition ωr=2ω1, where ωr is the sample rotation frequency and ω1 is the nutation frequency around an applied resonant radio frequency (rf) field. This resonance can be used for double-quantum filtering and measurement of homonuclear dipolar interactions in the presence of magic-angle spinning. The spin dynamics depend only weakly on crystallite orientation allowing good performance for powder samples. Chemical shift effects are suppressed to zeroth order. The method is demonstrated for singly and doubly 13C labeled L-alanine.

  4. Modernizing the MagIC Paleomagnetic and Rock Magnetic Database Technology Stack to Encourage Code Reuse and Reproducible Science

    NASA Astrophysics Data System (ADS)

    Minnett, R.; Koppers, A. A. P.; Jarboe, N.; Jonestrask, L.; Tauxe, L.; Constable, C.

    2016-12-01

    The Magnetics Information Consortium (https://earthref.org/MagIC/) develops and maintains a database and web application for supporting the paleo-, geo-, and rock magnetic scientific community. Historically, this objective has been met with an Oracle database and a Perl web application at the San Diego Supercomputer Center (SDSC). The Oracle Enterprise Cluster at SDSC, however, was decommissioned in July of 2016 and the cost for MagIC to continue using Oracle became prohibitive. This provided MagIC with a unique opportunity to reexamine the entire technology stack and data model. MagIC has developed an open-source web application using the Meteor (http://meteor.com) framework and a MongoDB database. The simplicity of the open-source full-stack framework that Meteor provides has improved MagIC's development pace and the increased flexibility of the data schema in MongoDB encouraged the reorganization of the MagIC Data Model. As a result of incorporating actively developed open-source projects into the technology stack, MagIC has benefited from their vibrant software development communities. This has translated into a more modern web application that has significantly improved the user experience for the paleo-, geo-, and rock magnetic scientific community.

  5. Advanced slow-magic angle spinning probe for magnetic resonance imaging and spectroscopy

    DOEpatents

    Wind, Robert A.; Hu, Jian Zhi; Minard, Kevin R.; Rommereim, Donald N.

    2006-01-24

    The present invention relates to a probe and processes useful for magnetic resonance imaging and spectroscopy instruments. More particularly, the invention relates to a MR probe and processes for obtaining resolution enhancements of fluid objects, including live specimens, using an ultra-slow (magic angle) spinning (MAS) of the specimen combined with a modified phase-corrected magic angle turning (PHORMAT) pulse sequence. Proton NMR spectra were measured of the torso and the top part of the belly of a female BALBc mouse in a 2T field, while spinning the animal at a speed of 1.5 Hz. Results show that even in this relatively low field with PHORMAT, an isotropic spectrum is obtained with line widths that are a factor 4.6 smaller than those obtained in a stationary mouse. Resolution of 1H NMR metabolite spectra are thus significantly enhanced. Results indicate that PHORMAT has the potential to significantly increase the utility of 1H NMR spectroscopy for in vivo biochemical, biomedical and/or medical applications involving large-sized biological objects such as mice, rats and even humans within a hospital setting. For small-sized objects, including biological objects, such as excised tissues, organs, live bacterial cells, and biofilms, use of PASS at a spinning rate of 30 Hz and above is preferred.

  6. End-compensated magnetostatic cavity for polarized 3He neutron spin filters.

    PubMed

    McIver, J W; Erwin, R; Chen, W C; Gentile, T R

    2009-06-01

    We have expanded upon the "Magic Box" concept, a coil driven magnetic parallel plate capacitor constructed out of mu-metal, by introducing compensation sections at the ends of the box that are tuned to limit end-effects similar to those of short solenoids. This ability has reduced the length of the magic box design without sacrificing any loss in field homogeneity, making the device far more applicable to the often space limited neutron beam line. The appeal of the design beyond affording longer polarized 3He lifetimes is that it provides a vertical guide field, which facilitates neutron spin transport for typical polarized beam experiments. We have constructed two end-compensated magic boxes of dimensions 28.4 x 40 x 15 cm3 (length x width x height) with measured, normalized volume-averaged transverse field gradients ranging from 3.3 x 10(-4) to 6.3 x 10(-4) cm(-1) for cell sizes ranging from 8.1 x 6.0 to 12.0 x 7.9 cm2 (diameter x length), respectively.

  7. Self-diffusion of electrolyte species in model battery electrodes using Magic Angle Spinning and Pulsed Field Gradient Nuclear Magnetic Resonance

    NASA Astrophysics Data System (ADS)

    Tambio, Sacris Jeru; Deschamps, Michaël; Sarou-Kanian, Vincent; Etiemble, Aurélien; Douillard, Thierry; Maire, Eric; Lestriez, Bernard

    2017-09-01

    Lithium-ion batteries are electrochemical storage devices using the electrochemical activity of the lithium ion in relation to intercalation compounds owing to mass transport phenomena through diffusion. Diffusion of the lithium ion in the electrode pores has been poorly understood due to the lack of experimental techniques for measuring its self-diffusion coefficient in porous media. Magic-Angle Spinning, Pulsed Field Gradient, Stimulated-Echo Nuclear Magnetic Resonance (MAS-PFG-STE NMR) was used here for the first time to measure the self-diffusion coefficients of the electrolyte species in the LP30 battery electrolyte (i.e. a 1 M solution of LiPF6 dissolved in 1:1 Ethylene Carbonate - Dimethyl Carbonate) in model composites. These composite electrodes were made of alumina, carbon black and PVdF-HFP. Alumina's magnetic susceptibility is close to the measured magnetic susceptibility of the LP30 electrolyte thereby limiting undesirable internal field gradients. Interestingly, the self-diffusion coefficient of lithium ions decreases with increasing carbon content. FIB-SEM was used to describe the 3D geometry of the samples. The comparison between the reduction of self-diffusion coefficients as measured by PFG-NMR and as geometrically derived from FIB/SEM tortuosity values highlights the contribution of specific interactions at the material/electrolyte interface on the lithium transport properties.

  8. Dynamic Nuclear Polarization-Enhanced Biomolecular NMR Spectroscopy at High Magnetic Field with Fast Magic-Angle Spinning.

    PubMed

    Jaudzems, Kristaps; Bertarello, Andrea; Chaudhari, Sachin R; Pica, Andrea; Cala-De Paepe, Diane; Barbet-Massin, Emeline; Pell, Andrew J; Akopjana, Inara; Kotelovica, Svetlana; Gajan, David; Ouari, Olivier; Tars, Kaspars; Pintacuda, Guido; Lesage, Anne

    2018-06-18

    Dynamic nuclear polarization (DNP) is a powerful way to overcome the sensitivity limitation of magic-angle-spinning (MAS) NMR experiments. However, the resolution of the DNP NMR spectra of proteins is compromised by severe line broadening associated with the necessity to perform experiments at cryogenic temperatures and in the presence of paramagnetic radicals. High-quality DNP-enhanced NMR spectra of the Acinetobacter phage 205 (AP205) nucleocapsid can be obtained by combining high magnetic field (800 MHz) and fast MAS (40 kHz). These conditions yield enhanced resolution and long coherence lifetimes allowing the acquisition of resolved 2D correlation spectra and of previously unfeasible scalar-based experiments. This enables the assignment of aromatic resonances of the AP205 coat protein and its packaged RNA, as well as the detection of long-range contacts, which are not observed at room temperature, opening new possibilities for structure determination. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. A New Interface for the Magnetics Information Consortium (MagIC) Paleo and Rock Magnetic Database

    NASA Astrophysics Data System (ADS)

    Jarboe, N.; Minnett, R.; Koppers, A. A. P.; Tauxe, L.; Constable, C.; Shaar, R.; Jonestrask, L.

    2014-12-01

    The Magnetic Information Consortium (MagIC) database (http://earthref.org/MagIC/) continues to improve the ease of uploading data, the creation of complex searches, data visualization, and data downloads for the paleomagnetic, geomagnetic, and rock magnetic communities. Data uploading has been simplified and no longer requires the use of the Excel SmartBook interface. Instead, properly formatted MagIC text files can be dragged-and-dropped onto an HTML 5 web interface. Data can be uploaded one table at a time to facilitate ease of uploading and data error checking is done online on the whole dataset at once instead of incrementally in an Excel Console. Searching the database has improved with the addition of more sophisticated search parameters and with the ability to use them in complex combinations. Searches may also be saved as permanent URLs for easy reference or for use as a citation in a publication. Data visualization plots (ARAI, equal area, demagnetization, Zijderveld, etc.) are presented with the data when appropriate to aid the user in understanding the dataset. Data from the MagIC database may be downloaded from individual contributions or from online searches for offline use and analysis in the tab delimited MagIC text file format. With input from the paleomagnetic, geomagnetic, and rock magnetic communities, the MagIC database will continue to improve as a data warehouse and resource.

  10. MagIC: Geomagnetic Applications from Earth History to Archeology

    NASA Astrophysics Data System (ADS)

    Constable, C.; Tauxe, L.; Koppers, A.; Minnett, R.; Jarboe, N.

    2016-12-01

    Major scientific challenges increasingly require an interdisciplinary approach, and highlight the need for open archives, incorporating visualization and analysis tools that are flexible enough to address novel research problems. Increasingly modern standards for publication are (or should be) demanding direct links to data, data citations, and adequate documentation that allow other researchers direct access to the fundamental measurements and analyses producing the results. Carefully documented metadata are essential and data models may need considerable complexity to accommodate re-use of observations originally collected with a different purpose in mind. The Magnetics Information Consortium (MagIC) provides an online home for all kinds of paleo-, archeo-magnetic, rock, and environmental magnetic data, from documentation of fieldwork, through lab protocols, to interpretations in terms of geomagnetic history. Examples of their application to understanding geomagnetic field behavior, archeological dating, and voyages of exploration to discover America will be used to highlight best practices and illustrate unexpected benefits of data archived using best practices with the goal of maintaining high standards for reproducibility.

  11. Uploading, Searching and Visualizing of Paleomagnetic and Rock Magnetic Data in the Online MagIC Database

    NASA Astrophysics Data System (ADS)

    Minnett, R.; Koppers, A.; Tauxe, L.; Constable, C.; Donadini, F.

    2007-12-01

    The Magnetics Information Consortium (MagIC) is commissioned to implement and maintain an online portal to a relational database populated by both rock and paleomagnetic data. The goal of MagIC is to archive all available measurements and derived properties from paleomagnetic studies of directions and intensities, and for rock magnetic experiments (hysteresis, remanence, susceptibility, anisotropy). MagIC is hosted under EarthRef.org at http://earthref.org/MAGIC/ and will soon implement two search nodes, one for paleomagnetism and one for rock magnetism. Currently the PMAG node is operational. Both nodes provide query building based on location, reference, methods applied, material type and geological age, as well as a visual map interface to browse and select locations. Users can also browse the database by data type or by data compilation to view all contributions associated with well known earlier collections like PINT, GMPDB or PSVRL. The query result set is displayed in a digestible tabular format allowing the user to descend from locations to sites, samples, specimens and measurements. At each stage, the result set can be saved and, where appropriate, can be visualized by plotting global location maps, equal area, XY, age, and depth plots, or typical Zijderveld, hysteresis, magnetization and remanence diagrams. User contributions to the MagIC database are critical to achieving a useful research tool. We have developed a standard data and metadata template (version 2.3) that can be used to format and upload all data at the time of publication in Earth Science journals. Software tools are provided to facilitate population of these templates within Microsoft Excel. These tools allow for the import/export of text files and provide advanced functionality to manage and edit the data, and to perform various internal checks to maintain data integrity and prepare for uploading. The MagIC Contribution Wizard at http://earthref.org/MAGIC/upload.htm executes the upload and takes only a few minutes to process tens of thousands of data records. The standardized MagIC template files are stored in the digital archives of EarthRef.org where they remain available for download by the public (in both text and Excel format). Finally, the contents of these template files are automatically parsed into the online relational database, making the data available for online searches in the paleomagnetic and rock magnetic search nodes. During the upload process the owner has the option of keeping the contribution private so it can be viewed in the context of other data sets and visualized using the suite of MagIC plotting tools. Alternatively, the new data can be password protected and shared with a group of users at the contributor's discretion. Once they are published and the owner is comfortable making the upload publicly accessible, the MagIC Editing Committee reviews the contribution for adherence to the MagIC data model and conventions to ensure a high level of data integrity.

  12. Managing Rock and Paleomagnetic Data Flow with the MagIC Database: from Measurement and Analysis to Comprehensive Archive and Visualization

    NASA Astrophysics Data System (ADS)

    Koppers, A. A.; Minnett, R. C.; Tauxe, L.; Constable, C.; Donadini, F.

    2008-12-01

    The Magnetics Information Consortium (MagIC) is commissioned to implement and maintain an online portal to a relational database populated by rock and paleomagnetic data. The goal of MagIC is to archive all measurements and derived properties for studies of paleomagnetic directions (inclination, declination) and intensities, and for rock magnetic experiments (hysteresis, remanence, susceptibility, anisotropy). Organizing data for presentation in peer-reviewed publications or for ingestion into databases is a time-consuming task, and to facilitate these activities, three tightly integrated tools have been developed: MagIC-PY, the MagIC Console Software, and the MagIC Online Database. A suite of Python scripts is available to help users port their data into the MagIC data format. They allow the user to add important metadata, perform basic interpretations, and average results at the specimen, sample and site levels. These scripts have been validated for use as Open Source software under the UNIX, Linux, PC and Macintosh© operating systems. We have also developed the MagIC Console Software program to assist in collating rock and paleomagnetic data for upload to the MagIC database. The program runs in Microsoft Excel© on both Macintosh© computers and PCs. It performs routine consistency checks on data entries, and assists users in preparing data for uploading into the online MagIC database. The MagIC website is hosted under EarthRef.org at http://earthref.org/MAGIC/ and has two search nodes, one for paleomagnetism and one for rock magnetism. Both nodes provide query building based on location, reference, methods applied, material type and geological age, as well as a visual FlashMap interface to browse and select locations. Users can also browse the database by data type (inclination, intensity, VGP, hysteresis, susceptibility) or by data compilation to view all contributions associated with previous databases, such as PINT, GMPDB or TAFI or other user-defined compilations. Query results are displayed in a digestible tabular format allowing the user to descend from locations to sites, samples, specimens and measurements. At each stage, the result set can be saved and, when supported by the data, can be visualized by plotting global location maps, equal area, XY, age, and depth plots, or typical Zijderveld, hysteresis, magnetization and remanence diagrams.

  13. Gd@Au15: A magic magnetic gold cluster for cancer therapy and bioimaging

    NASA Astrophysics Data System (ADS)

    Yadav, Brahm Deo; Kumar, Vijay

    2010-09-01

    We report from ab initio calculations a magic magnetic cage cluster of gold, Gd@Au15, obtained by doping of a Gd atom in gold clusters. It has a highest occupied molecular orbital-lowest unoccupied molecular orbital gap of 1.31 eV within the generalized gradient approximation that makes it a potential candidate for cancer therapy with an additional attractive feature that its large magnetic moment of 7 μB could be beneficial for magnetic resonance imaging.

  14. Improvements to the Magnetics Information Consortium (MagIC) Paleo and Rock Magnetic Database

    NASA Astrophysics Data System (ADS)

    Jarboe, N.; Minnett, R.; Tauxe, L.; Koppers, A. A. P.; Constable, C.; Jonestrask, L.

    2015-12-01

    The Magnetic Information Consortium (MagIC) database (http://earthref.org/MagIC/) continues to improve the ease of data uploading and editing, the creation of complex searches, data visualization, and data downloads for the paleomagnetic, geomagnetic, and rock magnetic communities. Online data editing is now available and the need for proprietary spreadsheet software is therefore entirely negated. The data owner can change values in the database or delete entries through an HTML 5 web interface that resembles typical spreadsheets in behavior and uses. Additive uploading now allows for additions to data sets to be uploaded with a simple drag and drop interface. Searching the database has improved with the addition of more sophisticated search parameters and with the facility to use them in complex combinations. A comprehensive summary view of a search result has been added for increased quick data comprehension while a raw data view is available if one desires to see all data columns as stored in the database. Data visualization plots (ARAI, equal area, demagnetization, Zijderveld, etc.) are presented with the data when appropriate to aid the user in understanding the dataset. MagIC data associated with individual contributions or from online searches may be downloaded in the tab delimited MagIC text file format for susbsequent offline use and analysis. With input from the paleomagnetic, geomagnetic, and rock magnetic communities, the MagIC database will continue to improve as a data warehouse and resource.

  15. Introducing a New Interface for the Online MagIC Database by Integrating Data Uploading, Searching, and Visualization

    NASA Astrophysics Data System (ADS)

    Jarboe, N.; Minnett, R.; Constable, C.; Koppers, A. A.; Tauxe, L.

    2013-12-01

    The Magnetics Information Consortium (MagIC) is dedicated to supporting the paleomagnetic, geomagnetic, and rock magnetic communities through the development and maintenance of an online database (http://earthref.org/MAGIC/), data upload and quality control, searches, data downloads, and visualization tools. While MagIC has completed importing some of the IAGA paleomagnetic databases (TRANS, PINT, PSVRL, GPMDB) and continues to import others (ARCHEO, MAGST and SECVR), further individual data uploading from the community contributes a wealth of easily-accessible rich datasets. Previously uploading of data to the MagIC database required the use of an Excel spreadsheet using either a Mac or PC. The new method of uploading data utilizes an HTML 5 web interface where the only computer requirement is a modern browser. This web interface will highlight all errors discovered in the dataset at once instead of the iterative error checking process found in the previous Excel spreadsheet data checker. As a web service, the community will always have easy access to the most up-to-date and bug free version of the data upload software. The filtering search mechanism of the MagIC database has been changed to a more intuitive system where the data from each contribution is displayed in tables similar to how the data is uploaded (http://earthref.org/MAGIC/search/). Searches themselves can be saved as a permanent URL, if desired. The saved search URL could then be used as a citation in a publication. When appropriate, plots (equal area, Zijderveld, ARAI, demagnetization, etc.) are associated with the data to give the user a quicker understanding of the underlying dataset. The MagIC database will continue to evolve to meet the needs of the paleomagnetic, geomagnetic, and rock magnetic communities.

  16. Migration to Current Open Source Technologies by MagIC Enables a More Responsive Website, Quicker Development Times, and Increased Community Engagement

    NASA Astrophysics Data System (ADS)

    Jarboe, N.; Minnett, R.; Koppers, A.; Constable, C.; Tauxe, L.; Jonestrask, L.

    2017-12-01

    The Magnetics Information Consortium (MagIC) supports an online database for the paleo, geo, and rock magnetic communities ( https://earthref.org/MagIC ). Researchers can upload data into the archive and download data as selected with a sophisticated search system. MagIC has completed the transition from an Oracle backed, Perl based, server oriented website to an ElasticSearch backed, Meteor based thick client website technology stack. Using JavaScript on both the sever and the client enables increased code reuse and allows easy offloading many computational operations to the client for faster response. On-the-fly data validation, column header suggestion, and spreadsheet online editing are some new features available with the new system. The 3.0 data model, method codes, and vocabulary lists can be browsed via the MagIC website and more easily updated. Source code for MagIC is publicly available on GitHub ( https://github.com/earthref/MagIC ). The MagIC file format is natively compatible with the PmagPy ( https://github.com/PmagPy/PmagPy) paleomagnetic analysis software. MagIC files can now be downloaded from the database and viewed and interpreted in the PmagPy GUI based tool, pmag_gui. Changes or interpretations of the data can then be saved by pmag_gui in the MagIC 3.0 data format and easily uploaded to the MagIC database. The rate of new contributions to the database has been increasing with many labs contributing measurement level data for the first time in the last year. Over a dozen file format conversion scripts are available for translating non-MagIC measurement data files into the MagIC format for easy uploading. We will continue to work with more labs until the whole community has a manageable workflow for contributing their measurement level data. MagIC will continue to provide a global repository for archiving and retrieving paleomagnetic and rock magnetic data and, with the new system in place, be able to more quickly respond to the community's requests for changes and improvements.

  17. High-Resolution Magic-Angle-Spinning NMR and Magnetic Resonance Imaging Spectroscopies Distinguish Metabolome and Structural Properties of Maize Seeds from Plants Treated with Different Fertilizers and Arbuscular mycorrhizal fungi.

    PubMed

    Mazzei, Pierluigi; Cozzolino, Vincenza; Piccolo, Alessandro

    2018-03-21

    Both high-resolution magic-angle-spinning (HRMAS) and magnetic resonance imaging (MRI) NMR spectroscopies were applied here to identify the changes of metabolome, morphology, and structural properties induced in seeds (caryopses) of maize plants grown at field level under either mineral or compost fertilization in combination with the inoculation by arbuscular mycorrhizal fungi (AMF). The metabolome of intact caryopses was examined by HRMAS-NMR, while the morphological aspects, endosperm properties and seed water distribution were investigated by MRI. Principal component analysis (PCA) was applied to evaluate 1 H CPMG (Carr-Purcel-Meiboom-Gill) HRMAS spectra as well as several MRI-derived parameters ( T 1 , T 2 , and self-diffusion coefficients) of intact maize caryopses. PCA score-plots from spectral results indicated that both seeds metabolome and structural properties depended on the specific field treatment undergone by maize plants. Our findings show that a combination of multivariate statistical analyses with advanced and nondestructive NMR techniques, such as HRMAS and MRI, enables the evaluation of the effects induced on maize caryopses by different fertilization and management practices at field level. The spectroscopic approach adopted here may become useful for the objective appraisal of the quality of seeds produced under a sustainable agriculture.

  18. 1H MAS NMR (magic-angle spinning nuclear magnetic resonance) techniques for the quantitative determination of hydrogen types in solid catalysts and supports.

    PubMed

    Kennedy, Gordon J; Afeworki, Mobae; Calabro, David C; Chase, Clarence E; Smiley, Randolph J

    2004-06-01

    Distinct hydrogen species are present in important inorganic solids such as zeolites, silicoaluminophosphates (SAPOs), mesoporous materials, amorphous silicas, and aluminas. These H species include hydrogens associated with acidic sites such as Al(OH)Si, non-framework aluminum sites, silanols, and surface functionalities. Direct and quantitative methodology to identify, measure, and monitor these hydrogen species are key to monitoring catalyst activity, optimizing synthesis conditions, tracking post-synthesis structural modifications, and in the preparation of novel catalytic materials. Many workers have developed several techniques to address these issues, including 1H MAS NMR (magic-angle spinning nuclear magnetic resonance). 1H MAS NMR offers many potential advantages over other techniques, but care is needed in recognizing experimental limitations and developing sample handling and NMR methodology to obtain quantitatively reliable data. A simplified approach is described that permits vacuum dehydration of multiple samples simultaneously and directly in the MAS rotor without the need for epoxy, flame sealing, or extensive glovebox use. We have found that careful optimization of important NMR conditions, such as magnetic field homogeneity and magic angle setting are necessary to acquire quantitative, high-resolution spectra that accurately measure the concentrations of the different hydrogen species present. Details of this 1H MAS NMR methodology with representative applications to zeolites, SAPOs, M41S, and silicas as a function of synthesis conditions and post-synthesis treatments (i.e., steaming, thermal dehydroxylation, and functionalization) are presented.

  19. Magnetic nanoparticle-induced hyperthermia with appropriate payloads: Paul Ehrlich's "magic (nano)bullet" for cancer theranostics?

    PubMed

    Datta, N R; Krishnan, S; Speiser, D E; Neufeld, E; Kuster, N; Bodis, S; Hofmann, H

    2016-11-01

    Effective multimodal cancer management requires the optimal integration of diagnostic and therapeutic modalities. Radiation therapy, chemotherapy and immunotherapy, alone or in combination, are integral parts of various cancer treatment protocols. Hyperthermia at 39-45°C is a potent radiosensitiser and has been shown to improve therapeutic outcomes in various tumours through its synergy with chemotherapy. Gene silencing approaches, using small interfering RNAs and microRNAs, are also being explored in clinical trials in oncology. The rapid developments in multifunctional nanoparticles provide ample opportunities to integrate both diagnostic and therapeutic modalities into a single effective cancer "theranostic" vector. Nanoparticles could extravasate passively into the tumour tissues in preference to the adjacent normal tissues by capitalizing on the enhanced permeability and retention effect. Tumour targeting might be further augmented by conjugating tumour-specific peptides and antibodies onto the surface of these nanoparticles or by activation through electromagnetic radiations, laser or ultrasound. Magnetic nanoparticles can induce hyperthermia in the presence of an alternating magnetic field, thereby multifunctionally with tumour-specific payloads empowering tumour specific radiotheranostics (for both imaging and radiotherapy), chemotherapy drug delivery, immunotherapy and gene silencing therapy. Such a (nano)bullet could realise the "magic bullet" conceived by Paul Ehrlich more than a century ago. This article discusses the various aspects of this "magic (nano)bullet" and the challenges that need to be addressed to usher in this new paradigm in modern cancer diagnostics and therapeutics. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Sealed magic angle spinning nuclear magnetic resonance probe and process for spectroscopy of hazardous samples

    DOEpatents

    Cho, Herman M.; Washton, Nancy M.; Mueller, Karl T.; Sears, Jr., Jesse A.; Townsend, Mark R.; Ewing, James R.

    2016-06-14

    A magic-angle-spinning (MAS) nuclear magnetic resonance (NMR) probe is described that includes double containment enclosures configured to seal and contain hazardous samples for analysis. The probe is of a modular design that ensures containment of hazardous samples during sample analysis while preserving spin speeds for superior NMR performance and convenience of operation.

  1. Trial wave functions for ring-trapped ions and neutral atoms: Microscopic description of the quantum space-time crystal

    NASA Astrophysics Data System (ADS)

    Yannouleas, Constantine; Landman, Uzi

    2017-10-01

    A constructive theoretical platform for the description of quantum space-time crystals uncovers for N interacting and ring-confined rotating particles the existence of low-lying states with proper space-time crystal behavior. The construction of the corresponding many-body trial wave functions proceeds first via symmetry breaking at the mean-field level followed by symmetry restoration using projection techniques. The ensuing correlated many-body wave functions are stationary states and preserve the rotational symmetries, and at the same time they reflect the point-group symmetries of the mean-field crystals. This behavior results in the emergence of sequences of select magic angular momenta Lm. For angular-momenta away from the magic values, the trial functions vanish. Symmetry breaking beyond the mean-field level can be induced by superpositions of such good-Lm many-body stationary states. We show that superposing a pair of adjacent magic angular momenta states leads to formation of special broken-symmetry states exhibiting quantum space-time-crystal behavior. In particular, the corresponding particle densities rotate around the ring, showing undamped and nondispersed periodic crystalline evolution in both space and time. The experimental synthesis of such quantum space-time-crystal wave packets is predicted to be favored in the vicinity of ground-state energy crossings of the Aharonov-Bohm-type spectra accessed via an externally applied, natural or synthetic, magnetic field. These results are illustrated here for Coulomb-repelling fermionic ions and for a lump of contact-interaction attracting bosons.

  2. Hall Plateaus at magic angles in ultraquantum Bismuth

    NASA Astrophysics Data System (ADS)

    Benoît, Fauqué.

    2009-03-01

    The behaviour of a three-dimensional electron gas in the presence of a magnetic field strong enough to put all carriers in the first Landau level (i.e. beyond the quantum limit) is a longstanding question of theoretical condensed matter physics [1]. This issue has been recently explored by two high-field experiments on elemental semi-metal Bismuth. In a first study of transport coefficients (which are dominated by hole-like carriers), the Nernst coefficient presented three unexpected maxima that are concomitant with quasi-plateaux in the Hall coefficient [2]. In a second series of experiments, torque magnetometry (which mainly probes the three Dirac valley electron pockets) detected a field-induced phase transition [3]. The full understanding of the electron and hole behaviours above the quantum limit of pure Bi is therefore still under debate. In this talk, we will present our measurement of the Hall resistivity and torque magnetometry with magnetic field up to 31 T and rotating in the trigonal-bisectrix plane [4]. The Hall response is dominated by the hole pockets according to its sign as well as the period and the angular dependence of its quantum oscillations. In the vicinity of the quantum limit, it presents additional anomalies which are the fingerprints of the electron pockets. We found that for particular orientations of the magnetic field (namely ``magic angles''), the Hall response becomes field-independent within the experimental resolution around 20T. This drastic dependence of the plateaux on the field orientation provides strong constraints for theoretical scenarios. [4pt] [1] Bertrand I. Halperin, Japanese Journal of Applied Physics, 26, Supplement 26-3 (1987).[0pt] [2] Kamran Behnia, Luis Balicas, Yakov Kopelevich, Science, 317, 1729 (2008).[0pt] [3] Lu Li, J. G. Checkelsky, Y. S. Hor, C. Uher, A. F. Hebard, R. J. Cava, and N. P. Ong , Science, 321, 5888 (2008).[0pt] [4] Benoît Fauqu'e, Luis Balicas, Ilya Sheikin, Jean Paul Issi and Kamran Behnia, to be published

  3. RF Priming Experiments and Simulations of Magnetic Priming in Relativistic Magnetrons

    NASA Astrophysics Data System (ADS)

    White, W. M.; Gilgenbach, R. M.; Jones, M. C.; Neculaes, V. B.; Lau, Y. Y.; Jordan, N.; Pengvanich, P.; Edgar, R.; Hoff, B.; Spencer, T. A.; Price, D.

    2004-11-01

    We investigate 2 priming techniques in relativistic magnetrons for rapid startup and mode-locking: RF priming experiments with 0.1-1 MW from a 2nd magnetron; Magnetic-priming simulations by azimuthally-varying-axial magnetic field. Experiments utilize MELBA-C with a Titan 6-vane magnetron: V = -300kV, I = 1-10kA, e-beam T = 0.5 μs, microwave power = 100-500 MW, f= 1-1.3 GHz, base vacuum= 8.5 x 10-10 Torr. The AFRL RF priming magnetron is at 0.1-2 MW, 3 μsec, 1.27-1.32 GHz. About 0.2-0.3 MW is injected into 1 of 3 open coupling slots in the relativistic magnetron. Analysis of the relativistic magnetron's microwave output shows a clear effect of RF priming. Simulations of magnetic priming in the pi-mode are run in MAGIC code by imposing N/2 azimuthal-variations in the axial magnetic field of an N-vane magnetron. Faster startup and mode-locking are simulated by rapid-electron spoke formation and excitation of RF fields.

  4. Lenz's Law Magic Trick

    NASA Astrophysics Data System (ADS)

    Ruiz, Michael J.

    2006-02-01

    The demonstration of Lenz's law by dropping a powerful magnet down a nonmagnetic metal pipe has become a classic lecture-hall demonstration.1,2 An inexpensive version is packaged as a professional magic trick3 called "Newton's Nightmare." Combining sleight-of-hand with a demonstration of Lenz's law is a surefire way to heighten student interest. The subsequent student discussion motivated by a desire to understand the magic trick can lead to a memorable physics lesson. This paper will discuss Lenz's law magic and review literature that reveals the subtlety of the physics.

  5. Laser frequency stabilization by light shift of optical-magnetic double resonances

    NASA Astrophysics Data System (ADS)

    Zhan, Yuanzhi; Peng, Xiang; Lin, Zaisheng; Gong, Wei; Guo, Hong

    2015-05-01

    This work adopts the light shift of optical-magnetic double resonance frequency in metastable-state 4He atoms to lock the laser center frequency to the magic point. At this magic frequency, both the left-circularly and right-circularly optical pumping processes will give the same value of optical-magnetic double resonance. With this method and after locking, experimental results show that the laser frequency fluctuation is dramatically reduced to 2.79 MHz in 3600 seconds, comparing with 34.1 MHz drift in the free running mode. In application, with the locked magic laser frequency, the heading error for laser pumped 4He magnetometer can be eliminated much. The National Science Fund for Distinguished Young Scholars of China (Grant No. 61225003), the National Natural Science Foundation of China (Grant No. 61101081), and the National Hi-Tech Research and Development (863) Program.

  6. NMR high-resolution magic angle spinning rotor design for quantification of metabolic concentrations

    NASA Astrophysics Data System (ADS)

    Holly, R.; Damyanovich, A.; Peemoeller, H.

    2006-05-01

    A new high-resolution magic angle spinning nuclear magnetic resonance technique is presented to obtain absolute metabolite concentrations of solutions. The magnetic resonance spectrum of the sample under investigation and an internal reference are acquired simultaneously, ensuring both spectra are obtained under the same experimental conditions. The robustness of the technique is demonstrated using a solution of creatine, and it is shown that the technique can obtain solution concentrations to within 7% or better.

  7. Design studies of the Ku-band, wide-band Gyro-TWT amplifier

    NASA Astrophysics Data System (ADS)

    Jung, Sang Wook; Lee, Han Seul; Jang, Kwong Ho; Choi, Jin Joo; Hong, Yong Jun; Shin, Jin Woo; So, Jun Ho; Won, Jong Hyo

    2014-02-01

    This paper reports a Ku-band, wide band Gyrotron-Traveling-wave-tube(Gyro-TWT) that is currently being developed at Kwangwoon University. The Gyro-TWT has a two stage linear tapered interaction circuit to obtain a wide operating bandwidth. The linearly-tapered interaction circuit and nonlinearly-tapered magnetic field gives the Gyro-TWT a wide operating bandwidth. The Gyro-TWT bandwidth is 23%. The 2d-Particle-in-cell(PIC) and MAGIC2d code simulation results are 17.3 dB and 24.34 kW, respectively for the maximum saturated output power. A double anode MIG was simulated with E-Gun code. The results were 0.7 for the transvers to the axial beam velocity ratio (=alpha) and a 2.3% axial velocity spread at 50 kV and 4 A. A magnetic field profile simulation was performed by using the Poisson code to obtain the grazing magnetic field of the entire interaction circuit with Poisson code.

  8. The Muon g - 2 experiment at Fermilab

    NASA Astrophysics Data System (ADS)

    Mott, James; Muon g - 2 experiment

    2017-06-01

    The Muon g - 2 experiment at Fermilab will measure the anomalous magnetic moment of the muon to a precision of 140 ppb, reducing the experimental uncertainty by a factor of 4 compared to the previous measurement at BNL (E821). The measurement technique adopts the storage ring concept used for E821, with magic-momentum muons stored in a highly uniform 1.45 T magnetic dipole field. The spin precession frequency is extracted from an analysis of the modulation of the rate of higher-energy positrons from muon decays, detected by 24 calorimeters and 3 straw tracking detectors. Compared to the E821 experiment, muon beam preparation, storage ring internal hardware, field measuring equipment, and detector and electronics systems are all new or significantly upgraded. Herein, I report on the status of the experiment as of Sept. 2016, presenting the magnetic field uniformity results after the completion of the first round of shimming and outlining the construction progress of the main detector systems.

  9. The Muon g $-$ 2 experiment at Fermilab

    DOE PAGES

    Mott, James

    2017-06-21

    Here, the Muon g-2 experiment at Fermilab will measure the anomalous magnetic moment of the muon to a precision of 140 ppb, reducing the experimental uncertainty by a factor of 4 compared to the previous measurement at BNL (E821). The measurement technique adopts the storage ring concept used for E821, with magic-momentum muons stored in a highly uniform 1.45 T magnetic dipole field. The spin precession frequency is extracted from an analysis of the modulation of the rate of higher-energy positrons from muon decays, detected by 24 calorimeters and 3 straw tracking detectors. Compared to the E821 experiment, muon beammore » preparation, storage ring internal hardware, field measuring equipment, and detector and electronics systems are all new or significantly upgraded. Herein, I report on the status of the experiment as of Sept. 2016, presenting the magnetic field uniformity results after the completion of the first round of shimming and outlining the construction progress of the main detector systems.« less

  10. The Muon g $-$ 2 experiment at Fermilab

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mott, James

    Here, the Muon g-2 experiment at Fermilab will measure the anomalous magnetic moment of the muon to a precision of 140 ppb, reducing the experimental uncertainty by a factor of 4 compared to the previous measurement at BNL (E821). The measurement technique adopts the storage ring concept used for E821, with magic-momentum muons stored in a highly uniform 1.45 T magnetic dipole field. The spin precession frequency is extracted from an analysis of the modulation of the rate of higher-energy positrons from muon decays, detected by 24 calorimeters and 3 straw tracking detectors. Compared to the E821 experiment, muon beammore » preparation, storage ring internal hardware, field measuring equipment, and detector and electronics systems are all new or significantly upgraded. Herein, I report on the status of the experiment as of Sept. 2016, presenting the magnetic field uniformity results after the completion of the first round of shimming and outlining the construction progress of the main detector systems.« less

  11. Devices and process for high-pressure magic angle spinning nuclear magnetic resonance

    DOEpatents

    Hoyt, David W; Sears, Jr., Jesse A; Turcu, Romulus V.F.; Rosso, Kevin M; Hu, Jian Zhi

    2014-04-08

    A high-pressure magic angle spinning (MAS) rotor is detailed that includes a high-pressure sample cell that maintains high pressures exceeding 150 bar. The sample cell design minimizes pressure losses due to penetration over an extended period of time.

  12. Devices and process for high-pressure magic angle spinning nuclear magnetic resonance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hoyt, David W.; Sears, Jesse A.; Turcu, Romulus V. F.

    A high-pressure magic angle spinning (MAS) rotor is detailed that includes a high-pressure sample cell that maintains high pressures exceeding 150 bar. The sample cell design minimizes pressure losses due to penetration over an extended period of time.

  13. Discrete magic angle turning system, apparatus, and process for in situ magnetic resonance spectroscopy and imaging

    DOEpatents

    Hu, Jian Zhi [Richland, WA; Sears, Jr., Jesse A.; Hoyt, David W [Richland, WA; Wind, Robert A [Kennewick, WA

    2009-05-19

    Described are a "Discrete Magic Angle Turning" (DMAT) system, devices, and processes that combine advantages of both magic angle turning (MAT) and magic angle hopping (MAH) suitable, e.g., for in situ magnetic resonance spectroscopy and/or imaging. In an exemplary system, device, and process, samples are rotated in a clockwise direction followed by an anticlockwise direction of exactly the same amount. Rotation proceeds through an angle that is typically greater than about 240 degrees but less than or equal to about 360 degrees at constant speed for a time applicable to the evolution dimension. Back and forth rotation can be synchronized and repeated with a special radio frequency (RF) pulse sequence to produce an isotropic-anisotropic shift 2D correlation spectrum. The design permits tubes to be inserted into the sample container without introducing plumbing interferences, further allowing control over such conditions as temperature, pressure, flow conditions, and feed compositions, thus permitting true in-situ investigations to be carried out.

  14. Interdisciplinary Collaboration amongst Colleagues and between Initiatives with the Magnetics Information Consortium (MagIC) Database

    NASA Astrophysics Data System (ADS)

    Minnett, R.; Koppers, A. A. P.; Jarboe, N.; Tauxe, L.; Constable, C.; Jonestrask, L.; Shaar, R.

    2014-12-01

    Earth science grand challenges often require interdisciplinary and geographically distributed scientific collaboration to make significant progress. However, this organic collaboration between researchers, educators, and students only flourishes with the reduction or elimination of technological barriers. The Magnetics Information Consortium (http://earthref.org/MagIC/) is a grass-roots cyberinfrastructure effort envisioned by the geo-, paleo-, and rock magnetic scientific community to archive their wealth of peer-reviewed raw data and interpretations from studies on natural and synthetic samples. MagIC is dedicated to facilitating scientific progress towards several highly multidisciplinary grand challenges and the MagIC Database team is currently beta testing a new MagIC Search Interface and API designed to be flexible enough for the incorporation of large heterogeneous datasets and for horizontal scalability to tens of millions of records and hundreds of requests per second. In an effort to reduce the barriers to effective collaboration, the search interface includes a simplified data model and upload procedure, support for online editing of datasets amongst team members, commenting by reviewers and colleagues, and automated contribution workflows and data retrieval through the API. This web application has been designed to generalize to other databases in MagIC's umbrella website (EarthRef.org) so the Geochemical Earth Reference Model (http://earthref.org/GERM/) portal, Seamount Biogeosciences Network (http://earthref.org/SBN/), EarthRef Digital Archive (http://earthref.org/ERDA/) and EarthRef Reference Database (http://earthref.org/ERR/) will benefit from its development.

  15. RADLAC 2 performance summary

    NASA Astrophysics Data System (ADS)

    Shope, S. L.; Mazarakis, M. G.; Frost, C. A.; Crist, C. E.; Poukey, J. W.; Prestwich, K. R.; Turman, B. N.; Struve, K.; Welch, D.

    1991-09-01

    A 12.5-m long Self Magnetically Insulated Transmission LinE (SMILE) that sums the voltages of eight, 2-MV pulse forming lines was installed in the RADLAC-2 linear introduction accelerator. The magnetic insulation criteria were calculated using parapotential flow theory and found to agree with MAGIC simulations. High quality annular beams with a transverse velocity beta (perpendicular) equals v(perpendicular)/c is less than or equal to 0.1 and a radius r(sub b) less than 2 cm were measured for currents of 50 to 100 kA extracted from a magnetic immersed foilless diode. These parameters were achieved with 11 to 15-MV accelerating voltages and 6 to 16-kG diode magnetic fields. The experimental results exceeded our design expectations and are in good agreement with code simulations.

  16. Magic Numbers in Small Iron Clusters: A First-Principles Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Eunja; Mohrland, Andrew B.; Weck, Philippe F.

    2014-10-03

    We perform ab initio spin-polarized density functional calculations of Fen aggregates with n ≤ 17 atoms to reveal the origin of the observed magic numbers, which indicate particularly high stability of clusters with 7, 13 and 15 atoms. Our results clarify the controversy regarding the ground state geometry of clusters such as Fe5and indicate that magnetism plays an important role in determining the stability and magic numbers in small iron clusters.

  17. Nuclear Magnetic Resonance Spectroscopy Applications: Proton NMR In Biological Objects Subjected To Magic Angle Spinning

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wind, Robert A.; Hu, Jian Zhi

    2005-01-01

    Proton NMR in Biological Objects Submitted to Magic Angle Spinning, In Encyclopedia of Analytical Science, Second Edition (Paul J. Worsfold, Alan Townshend and Colin F. Poole, eds.), Elsevier, Oxford 6:333-342. Published January 1, 2005. Proposal Number 10896.

  18. Monte Carlo simulation of the dose response of a novel 2D silicon diode array for use in hybrid MRI-LINAC systems.

    PubMed

    Gargett, Maegan; Oborn, Brad; Metcalfe, Peter; Rosenfeld, Anatoly

    2015-02-01

    MRI-guided radiation therapy systems (MRIgRT) are being developed to improve online imaging during treatment delivery. At present, the operation of single point dosimeters and an ionization chamber array have been characterized in such systems. This work investigates a novel 2D diode array, named "magic plate," for both single point calibration and 2D positional performance, the latter being a key element of modern radiotherapy techniques that will be delivered by these systems. geant4 Monte Carlo methods have been employed to study the dose response of a silicon diode array to 6 MV photon beams, in the presence of in-line and perpendicularly aligned uniform magnetic fields. The array consists of 121 silicon diodes (dimensions 1.5 × 1.5 × 0.38 mm(3)) embedded in kapton substrate with 1 cm pitch, spanning a 10 × 10 cm(2) area in total. A geometrically identical, water equivalent volume was simulated concurrently for comparison. The dose response of the silicon diode array was assessed for various photon beam field shapes and sizes, including an IMRT field, at 1 T. The dose response was further investigated at larger magnetic field strengths (1.5 and 3 T) for a 4 × 4 cm(2) photon field size. The magic plate diode array shows excellent correspondence (< ± 1%) to water dose in the in-line orientation, for all beam arrangements and magnetic field strengths investigated. The perpendicular orientation, however, exhibits a dose shift with respect to water at the high-dose-gradient beam edge of jaw-defined fields [maximum (4.3 ± 0.8)% over-response, maximum (1.8 ± 0.8)% under-response on opposing side for 1 T, uncertainty 1σ]. The trend is not evident in areas with in-field dose gradients typical of IMRT dose maps. A novel 121 pixel silicon diode array detector has been characterized by Monte Carlo simulation for its performance inside magnetic fields representative of current prototype and proposed MRI-linear accelerator systems. In the in-line orientation, the silicon dose is directly proportional to the water dose. In the perpendicular orientation, there is a shift in dose response relative to water in the highest dose gradient regions, at the edge of jaw-defined and single-segment MLC fields. The trend was not observed in-field for an IMRT beam. The array is expected to be a valuable tool in MRIgRT dosimetry.

  19. Monte Carlo simulation of the dose response of a novel 2D silicon diode array for use in hybrid MRI–LINAC systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gargett, Maegan, E-mail: mg406@uowmail.edu.au; Rosenfeld, Anatoly; Oborn, Brad

    2015-02-15

    Purpose: MRI-guided radiation therapy systems (MRIgRT) are being developed to improve online imaging during treatment delivery. At present, the operation of single point dosimeters and an ionization chamber array have been characterized in such systems. This work investigates a novel 2D diode array, named “magic plate,” for both single point calibration and 2D positional performance, the latter being a key element of modern radiotherapy techniques that will be delivered by these systems. Methods: GEANT4 Monte Carlo methods have been employed to study the dose response of a silicon diode array to 6 MV photon beams, in the presence of in-linemore » and perpendicularly aligned uniform magnetic fields. The array consists of 121 silicon diodes (dimensions 1.5 × 1.5 × 0.38 mm{sup 3}) embedded in kapton substrate with 1 cm pitch, spanning a 10 × 10 cm{sup 2} area in total. A geometrically identical, water equivalent volume was simulated concurrently for comparison. The dose response of the silicon diode array was assessed for various photon beam field shapes and sizes, including an IMRT field, at 1 T. The dose response was further investigated at larger magnetic field strengths (1.5 and 3 T) for a 4 × 4 cm{sup 2} photon field size. Results: The magic plate diode array shows excellent correspondence (< ± 1%) to water dose in the in-line orientation, for all beam arrangements and magnetic field strengths investigated. The perpendicular orientation, however, exhibits a dose shift with respect to water at the high-dose-gradient beam edge of jaw-defined fields [maximum (4.3 ± 0.8)% over-response, maximum (1.8 ± 0.8)% under-response on opposing side for 1 T, uncertainty 1σ]. The trend is not evident in areas with in-field dose gradients typical of IMRT dose maps. Conclusions: A novel 121 pixel silicon diode array detector has been characterized by Monte Carlo simulation for its performance inside magnetic fields representative of current prototype and proposed MRI–linear accelerator systems. In the in-line orientation, the silicon dose is directly proportional to the water dose. In the perpendicular orientation, there is a shift in dose response relative to water in the highest dose gradient regions, at the edge of jaw-defined and single-segment MLC fields. The trend was not observed in-field for an IMRT beam. The array is expected to be a valuable tool in MRIgRT dosimetry.« less

  20. Magnetic resonance imaging of DNP enhancements in a rotor spinning at the magic angle

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Perras, Frederic A.; Kobayashi, Takeshi; Pruski, Marek

    Simulations performed on model, static, samples have shown that the microwave power is non-uniformly distributed in the magic angle spinning (MAS) rotor when using conventional dynamic nuclear polarization (DNP) instrumentation. Here, we applied the stray-field magic angle spinning imaging (STRAFI–MAS) experiment to generate a spatial map of the DNP enhancements in a full rotor, which is spun at a low rate in a commercial DNP–MAS NMR system. Notably, we observed that the enhancement factors produced in the center of the rotor can be twice as large as those produced at the top of the rotor. Surprisingly, we observed that themore » largest enhancement factors are observed along the axis of the rotor as opposed to against its walls, which are most directly irradiated by the microwave beam. We lastly observed that the distribution of enhancement factors can be moderately improved by degassing the sample and increasing the microwave power. The inclusion of dielectric particles greatly amplifies the enhancement factors throughout the rotor. Furthermore, the STRAFI–MAS approach can provide useful guidance for optimizing the access of microwave power to the sample, and thereby lead to further increases in sensitivity of DNP–MAS NMR.« less

  1. Magnetic resonance imaging of DNP enhancements in a rotor spinning at the magic angle

    DOE PAGES

    Perras, Frederic A.; Kobayashi, Takeshi; Pruski, Marek

    2016-02-23

    Simulations performed on model, static, samples have shown that the microwave power is non-uniformly distributed in the magic angle spinning (MAS) rotor when using conventional dynamic nuclear polarization (DNP) instrumentation. Here, we applied the stray-field magic angle spinning imaging (STRAFI–MAS) experiment to generate a spatial map of the DNP enhancements in a full rotor, which is spun at a low rate in a commercial DNP–MAS NMR system. Notably, we observed that the enhancement factors produced in the center of the rotor can be twice as large as those produced at the top of the rotor. Surprisingly, we observed that themore » largest enhancement factors are observed along the axis of the rotor as opposed to against its walls, which are most directly irradiated by the microwave beam. We lastly observed that the distribution of enhancement factors can be moderately improved by degassing the sample and increasing the microwave power. The inclusion of dielectric particles greatly amplifies the enhancement factors throughout the rotor. Furthermore, the STRAFI–MAS approach can provide useful guidance for optimizing the access of microwave power to the sample, and thereby lead to further increases in sensitivity of DNP–MAS NMR.« less

  2. Spinning angle optical calibration apparatus

    DOEpatents

    Beer, Stephen K.; Pratt, II, Harold R.

    1991-01-01

    An optical calibration apparatus is provided for calibrating and reproducing spinning angles in cross-polarization, nuclear magnetic resonance spectroscopy. An illuminated magnifying apparatus enables optical setting an accurate reproducing of spinning "magic angles" in cross-polarization, nuclear magnetic resonance spectroscopy experiments. A reference mark scribed on an edge of a spinning angle test sample holder is illuminated by a light source and viewed through a magnifying scope. When the "magic angle" of a sample material used as a standard is attained by varying the angular position of the sample holder, the coordinate position of the reference mark relative to a graduation or graduations on a reticle in the magnifying scope is noted. Thereafter, the spinning "magic angle" of a test material having similar nuclear properties to the standard is attained by returning the sample holder back to the originally noted coordinate position.

  3. Dipolar filtered magic-sandwich-echoes as a tool for probing molecular motions using time domain NMR

    NASA Astrophysics Data System (ADS)

    Filgueiras, Jefferson G.; da Silva, Uilson B.; Paro, Giovanni; d'Eurydice, Marcel N.; Cobo, Márcio F.; deAzevedo, Eduardo R.

    2017-12-01

    We present a simple 1 H NMR approach for characterizing intermediate to fast regime molecular motions using 1 H time-domain NMR at low magnetic field. The method is based on a Goldmann Shen dipolar filter (DF) followed by a Mixed Magic Sandwich Echo (MSE). The dipolar filter suppresses the signals arising from molecular segments presenting sub kHz mobility, so only signals from mobile segments are detected. Thus, the temperature dependence of the signal intensities directly evidences the onset of molecular motions with rates higher than kHz. The DF-MSE signal intensity is described by an analytical function based on the Anderson Weiss theory, from where parameters related to the molecular motion (e.g. correlation times and activation energy) can be estimated when performing experiments as function of the temperature. Furthermore, we propose the use of the Tikhonov regularization for estimating the width of the distribution of correlation times.

  4. Science meets magic: photonic metamaterials

    NASA Astrophysics Data System (ADS)

    Ozbay, Ekmel

    2012-05-01

    The word "magic" is usually associated with movies, fiction, children stories, etc. but seldom with the natural sciences. Recent advances in metamaterials have changed this notion, in which we can now speak of "almost magical" properties that scientists could only dream about only a decade ago. In this article, we review some of the recent "almost magical" progress in the field of meta-materials.

  5. Science meets magic: photonic metamaterials

    NASA Astrophysics Data System (ADS)

    Ozbay, Ekmel

    2012-03-01

    The word "magic" is usually associated with movies, fiction, children stories, etc. but seldom with the natural sciences. Recent advances in metamaterials have changed this notion, in which we can now speak of "almost magical" properties that scientists could only dream about only a decade ago. In this article, we review some of the recent "almost magical" progress in the field of meta-materials.

  6. Cavity magnon polaritons with lithium ferrite and three-dimensional microwave resonators at millikelvin temperatures

    NASA Astrophysics Data System (ADS)

    Goryachev, Maxim; Watt, Stuart; Bourhill, Jeremy; Kostylev, Mikhail; Tobar, Michael E.

    2018-04-01

    Single crystal lithium ferrite (LiFe) spheres of sub-mm dimension are examined at mK temperatures, microwave frequencies, and variable dc magnetic field, for use in hybrid quantum systems and condensed matter and fundamental physics experiments. Strong coupling regimes of the photon-magnon interaction (cavity magnon polariton quasiparticles) were observed with coupling strength of up to 250 MHz at 9.5 GHz (2.6%) with magnon linewidths of order 4 MHz (with potential improvement to sub-MHz values). We show that the photon-magnon coupling can be significantly improved and exceed that of the widely used yttrium iron garnet crystal, due to the small unit cell of LiFe, allowing twice the spins per unit volume. Magnon mode softening was observed at low dc fields and, combined with the normal Zeeman effect, creates magnon spin-wave modes that are insensitive to first-order magnetic-field fluctuations. This effect is observed in the Kittel mode at 5.5 GHz (and another higher order mode at 6.5 GHz) with a dc magnetic field close to 0.19 tesla. We show that if the cavity is tuned close to this frequency, the magnon polariton particles exhibit an enhanced range of strong coupling and insensitivity to magnetic field fluctuations with both first-order and second-order insensitivity to magnetic field as a function of frequency (double magic point clock transition), which could potentially be exploited in cavity QED experiments.

  7. Klein tunneling in Weyl semimetals under the influence of magnetic field.

    PubMed

    Yesilyurt, Can; Tan, Seng Ghee; Liang, Gengchiau; Jalil, Mansoor B A

    2016-12-12

    Klein tunneling refers to the absence of normal backscattering of electrons even under the case of high potential barriers. At the barrier interface, the perfect matching of electron and hole wavefunctions enables a unit transmission probability for normally incident electrons. It is theoretically and experimentally well understood in two-dimensional relativistic materials such as graphene. Here we investigate the Klein tunneling effect in Weyl semimetals under the influence of magnetic field induced by ferromagnetic stripes placed at barrier boundaries. Our results show that the resonance of Fermi wave vector at specific barrier lengths gives rise to perfect transmission rings, i.e., three-dimensional analogue of the so-called magic transmission angles in two-dimensional Dirac semimetals. Besides, the transmission profile can be shifted by application of magnetic field in the central region, a property which may be utilized in electro-optic applications. When the applied potential is close to the Fermi level, a particular incident vector can be selected by tuning the magnetic field, thus enabling highly selective transmission of electrons in the bulk of Weyl semimetals. Our analytical and numerical calculations obtained by considering Dirac electrons in three regions and using experimentally feasible parameters can pave the way for relativistic tunneling applications in Weyl semimetals.

  8. Next Generation Muon g-2 Experiments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hertzog, David W.

    2015-12-02

    I report on the progress of two new muon anomalous magnetic moment experiments, which are in advanced design and construction phases. The goal of Fermilab E989 is to reduce the experimental uncertainty ofmore » $$a_\\mu$$ from Brookhaven E821 by a factor of 4; that is, $$\\delta a_\\mu \\sim 16 \\times 10^{-11}$$, a relative uncertainty of 140~ppb. The method follows the same magic-momentum storage ring concept used at BNL, and pioneered previously at CERN, but muon beam preparation, storage ring internal hardware, field measuring equipment, and detector and electronics systems are all new or upgraded significantly. In contrast, J-PARC E34 will employ a novel approach based on injection of an ultra-cold, low-energy, muon beam injected into a small, but highly uniform magnet. Only a small magnetic focusing field is needed to maintain storage, which distinguishes it from CERN, BNL and Fermilab. E34 aims to roughly match the previous BNL precision in their Phase~1 installation.« less

  9. Spinning angle optical calibration apparatus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beer, S.K.; Pratt, H.R. II.

    1989-09-12

    An optical calibration apparatus is provided for calibrating and reproducing spinning angles in cross-polarization, nuclear magnetic resonance spectroscopy. An illuminated magnifying apparatus enables optical setting and accurate reproducing of spinning magic angles in cross-polarization, nuclear magnetic resonance spectroscopy experiments. A reference mark scribed on an edge of a spinning angle test sample holder is illuminated by a light source and viewed through a magnifying scope. When the magic angle of a sample material used as a standard is attained by varying the angular position of the sample holder, the coordinate position of the reference mark relative to a graduation ormore » graduations on a reticle in the magnifying scope is noted. Thereafter, the spinning magic angle of a test material having similar nuclear properties to the standard is attained by returning the sample holder back to the originally noted coordinate position. 2 figs.« less

  10. On an algebraic structure of dimensionally reduced magical supergravity theories

    NASA Astrophysics Data System (ADS)

    Fukuchi, Shin; Mizoguchi, Shun'ya

    2018-06-01

    We study an algebraic structure of magical supergravities in three dimensions. We show that if the commutation relations among the generators of the quasi-conformal group in the super-Ehlers decomposition are in a particular form, then one can always find a parameterization of the group element in terms of various 3d bosonic fields that reproduces the 3d reduced Lagrangian of the corresponding magical supergravity. This provides a unified treatment of all the magical supergravity theories in finding explicit relations between the 3d dimensionally reduced Lagrangians and particular coset nonlinear sigma models. We also verify that the commutation relations of E 6 (+ 2), the quasi-conformal group for A = C, indeed satisfy this property, allowing the algebraic interpretation of the structure constants and scalar field functions as was done in the F 4 (+ 4) magical supergravity.

  11. Magnetic absorption of VHE photons in the magnetosphere of the Crab pulsar

    NASA Astrophysics Data System (ADS)

    Bogovalov, S. V.; Contopoulos, I.; Prosekin, A.; Tronin, I.; Aharonian, F. A.

    2018-05-01

    The detection of the pulsed ˜1 TeV gamma-ray emission from the Crab pulsar reported by MAGIC and VERITAS collaborations demands a substantial revision of existing models of particle acceleration in the pulsar magnetosphere. In this regard model independent restrictions on the possible production site of the very high energy (VHE) photons become an important issue. In this paper, we consider limitations imposed by the process of conversion of VHE gamma-rays into e± pairs in the magnetic field of the pulsar magnetosphere. Photons with energies exceeding 1 TeV are effectively absorbed even at large distances from the surface of the neutron star. Our calculations of magnetic absorption in the force-free magnetosphere show that the twisting of the magnetic field due to the pulsar rotation makes the magnetosphere more transparent compared to the dipole magnetosphere. The gamma-ray absorption appears stronger for photons emitted in the direction of rotation than in the opposite direction. There is a small angular cone inside which the magnetosphere is relatively transparent and photons with energy 1.5 TeV can escape from distances beyond 0.1 light cylinder radius (Rlc). The emission surface from where photons can be emitted in the observer's direction further restricts the sites of VHE gamma-ray production. For the observation angle 57° relative to the Crab pulsar axis of rotation and the orthogonal rotation, the emission surface in the open field line region is located as close as 0.4 Rlc from the stellar surface for a dipole magnetic field, and 0.1 Rlc for a force-free magnetic field.

  12. "The Crux and the Magic": The Political History of Boston Magnet Schools, 1968-1989

    ERIC Educational Resources Information Center

    Gelber, Scott

    2008-01-01

    This study analyzes public perceptions of Boston's magnet school program. Typically evaluated in terms of their impact on racial integration, magnet schools also were designed to improve the tarnished image of the Boston school system. While promoting voluntary integration at a handful of schools, the magnet program struggled to change the…

  13. Magic wavelengths of the Ca+ ion for circularly polarized light

    NASA Astrophysics Data System (ADS)

    Jiang, Jun; Jiang, Li; Wang, Xia; Zhang, Deng-Hong; Xie, Lu-You; Dong, Chen-Zhong

    2017-10-01

    The dynamic dipole polarizabilities of low-lying states of Ca+ ions for circularly polarized light are calculated by using the relativistic configuration interaction plus core polarization approach. The magic wavelengths are determined for the magnetic sublevel transitions 4 s1/2 ,m→4 pj',m' and 4 s1/2 ,m→3 dj',m' with total angular momentum j' and its components m'. In contrast to the case of linearly polarized light, several additional magic wavelengths are found for these transitions. We suggest that accurate measurements on the magic wavelengths near 851 nm for the 4 s1/2 ,m→4 p3/2 ,m' transitions can be used to determine the ratio of the oscillator strengths for the 4 p3/2→3 d3/2 and 4 p3/2→3 d5/2 transitions.

  14. Maximally Entangled States of a Two-Qubit System

    NASA Astrophysics Data System (ADS)

    Singh, Manu P.; Rajput, B. S.

    2013-12-01

    Entanglement has been explored as one of the key resources required for quantum computation, the functional dependence of the entanglement measures on spin correlation functions has been established, correspondence between evolution of maximally entangled states (MES) of two-qubit system and representation of SU(2) group has been worked out and the evolution of MES under a rotating magnetic field has been investigated. Necessary and sufficient conditions for the general two-qubit state to be maximally entangled state (MES) have been obtained and a new set of MES constituting a very powerful and reliable eigen basis (different from magic bases) of two-qubit systems has been constructed. In terms of the MES constituting this basis, Bell’s States have been generated and all the qubits of two-qubit system have been obtained. It has shown that a MES corresponds to a point in the SO(3) sphere and an evolution of MES corresponds to a trajectory connecting two points on this sphere. Analysing the evolution of MES under a rotating magnetic field, it has been demonstrated that a rotating magnetic field is equivalent to a three dimensional rotation in real space leading to the evolution of a MES.

  15. Is {sup 276}U a doubly magic nucleus?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liliani, N., E-mail: netta.liliani@gmail.com; Sulaksono, A.

    2016-04-19

    We investigate a possible new doubly magic heavy nucleus by using a relativistic mean-field (RMF) model with the addition of a cross interaction term of omega-rho mesons and an electromagnetic exchange term. We propose that {sup 276}U is a doubly magic nucleus. The evidence for {sup 276}U being a doubly magic nucleus is shown through the two-nucleon gaps, the single-particle energies, and the neutron skin thickness of the nucleus. We have also found that the prediction of {sup 276}U as a doubly magic nucleus by the RMF model is not affected by the inclusion of isoscalar-isovector and electromagnetic exchange couplings.

  16. Origin and Correction of Magnetic Field Inhomogeneity at the Interface in Biphasic NMR Samples

    PubMed Central

    Martin, Bryan T.; Chingas, G. C.

    2012-01-01

    The use of susceptibility matching to minimize spectral distortion of biphasic samples layered in a standard 5 mm NMR tube is described. The approach uses magic angle spinning (MAS) to first extract chemical shift differences by suppressing bulk magnetization. Then, using biphasic coaxial samples, magnetic susceptibilities are matched by titration with a paramagnetic salt. The matched phases are then layered in a standard NMR tube where they can be shimmed and examined. Line widths of two distinct spectral lines, selected to characterize homogeneity in each phase, are simultaneously optimized. Two-dimensional distortion-free, slice-resolved spectra of an octanol/water system illustrate the method. These data are obtained using a 2D stepped-gradient pulse sequence devised for this application. Advantages of this sequence over slice-selective methods are that acquisition efficiency is increased and processing requires only conventional software. PMID:22459062

  17. Spinning angle optical calibration apparatus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beer, S.K.; Pratt, H.R.

    1991-02-26

    This patent describes an optical calibration apparatus provided for calibrating and reproducing spinning angles in cross-polarization, nuclear magnetic resonance spectroscopy. An illuminated magnifying apparatus enables optical setting an accurate reproducing of spinning magic angles in cross-polarization, nuclear magnetic resonance spectroscopy experiments. A reference mark scribed on an edge of a spinning angle test sample holder is illuminated by a light source and viewed through a magnifying scope. When the magic angle of a sample material used as a standard is attained by varying the angular position of the sample holder, the coordinate position of the reference mark relative to amore » graduation or graduations on a reticle in the magnifying scope is noted.« less

  18. Magic star puzzle for educational mathematics

    NASA Astrophysics Data System (ADS)

    Gan, Yee Siang; Fong, Wan Heng; Sarmin, Nor Haniza

    2013-04-01

    One of the interesting fields in recreational mathematics is the magic number arrangement. There are different kinds of arrays in the arrangement for a group of numbers. In particular, one of the arrays in magic number arrangement is called magic star. In fact, magic star involves combinatorics that contributes to geometrical analysis and number theory. Hence, magic star is suitable to be introduced as educational mathematics to cultivate interest in different area of mathematics. To obtain the solutions of normal magic stars of order six, the possible sets of numbers for every line in a magic star have been considered. Previously, the calculation for obtaining the solutions has been done manually which is time-consuming. Therefore, a programming code to generate all the fundamental solutions for normal magic star of order six without including the properties of rotation and reflection has been done. In this puzzle, a magic star puzzle is created by using Matlab software, which enables a user to verify the entries for the cells of magic star of order six. Moreover, it is also user-friendly as it provides interactive commands on the inputs given by the user, which enables the user to detect the incorrect inputs. In addition, user can also choose to view all the fundamental solutions as generated by the programming code.

  19. Nuclear magnetic resonance studies of amino acids and proteins. Side-chain mobility of methionine in the crystalline amonio acid and in crystallne sperm whale (Physeter catodon) myoglobin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Keniry, M.A.; Rothgeb, T.M.; Smith, R.L.

    1983-04-12

    Deuterium (/sup 2/H) nuclear magnetic resonance (NMR) spectra and spin-lattice relaxation times (T/sub 1/) were obtained of L-(epsilon-/sup 2/H/sub 3/)methionine, L-(epsilon-/sup 2/H/sub 3/)methionine in a D,L lattice, and (S-methyl-/sup 2/H/sub 3/)methionine in the crystalline solid state, as a function of temperature, in addition to obtaining /sup 2/H T/sub 1/ and line-width results as a function of temperature on (epsilon-/sup 2/H/sub 3/)methionine-labeled sperm whale (Physeter catodon) myoglobins by using the method of magnetic ordering. Also recorded were /sup 13/C cross-polarization ''magic-angle'' sample-spinning NMR spectra of (epsilon-/sup 13/C)methionine-labeled crystalline cyanoferrimyoglobin (at 37.7 MHz, corresponding to a magnetic field strength of 3.52 T)more » and of the same protein in aqueous solution. (JMT)« less

  20. [The role of imagination in modern medicine].

    PubMed

    Schott, Heinz

    2004-06-01

    In Renaissance and early modern times, the concept of imagination (Latin imaginatio) was essential for the (natural) philosophical explanation of magic processes, especially in the anthropology of Paracelsus. He assumed that imagination was a natural vital power including cosmic, mental, phychical, and physical dimensions. The Paracelsians criticized traditional humor pathology ignoring their theory of' 'natural magic'. On the other hand, they were criticized by their adversaries as charlatans practicing 'black magic'. About 1800, in between enlightenment and romanticism, the healing concept of, animal magnetism' (Mesmerism) evoked an analogous debate, whether, magnetic' phenomena originated from a real (physical) power (so-called, fluidum') or were just due to fantasy or imagination (German Einbildungskraft). At the end of the 19th century, the French internist Hippolyte Bernheim created-against the background of medical hypnosis (hypnotism') as a consequence of Mesmerism - his theory of suggestion and autosuggestion: a new paradigm of psychological respectively psychosomatic medicine, which became the basis for the concept of, placebo' in modern biomedicine. From now on, all the effects of, alternative medicine' could easily be explained by the, placebo-effect', more or less founded - at least unconsciously - on fraud.

  1. Solid effect in magic angle spinning dynamic nuclear polarization

    NASA Astrophysics Data System (ADS)

    Corzilius, Björn; Smith, Albert A.; Griffin, Robert G.

    2012-08-01

    For over five decades, the solid effect (SE) has been heavily utilized as a mechanism for performing dynamic nuclear polarization (DNP). Nevertheless, it has not found widespread application in contemporary, high magnetic field DNP experiments because SE enhancements display an ω _0 ^{ - 2} field dependence. In particular, for nominally forbidden zero and double quantum SE transitions to be partially allowed, it is necessary for mixing of adjacent nuclear spin states to occur, and this leads to the observed field dependence. However, recently we have improved our instrumentation and report here an enhancement of ɛ = 91 obtained with the organic radical trityl (OX063) in magic angle spinning experiments performed at 5 T and 80 K. This is a factor of 6-7 higher than previous values in the literature under similar conditions. Because the solid effect depends strongly on the microwave field strength, we attribute this large enhancement to larger microwave field strengths inside the sample volume, achieved with more efficient coupling of the gyrotron to the sample chamber. In addition, we develop a theoretical model to explain the dependence of the buildup rate of enhanced nuclear polarization and the steady-state enhancement on the microwave power. Buildup times and enhancements were measured as a function of 1H concentration for both trityl and Gd-DOTA. Comparison of the results indicates that for trityl the initial polarization step is the slower, rate-determining step. However, for Gd-DOTA the spread of nuclear polarization via homonuclear 1H spin diffusion is rate-limiting. Finally, we discuss the applicability of the solid effect at fields > 5 T and the requirements to address the unfavorable field dependence of the solid effect.

  2. Spectra, composition and interactions of nuclei above 10 TeV using magnet-interferometric chambers (SCIN/MAGIC)

    NASA Technical Reports Server (NTRS)

    Wefel, John P.

    1991-01-01

    Initial definition studies were performed for the SCIN/MAGIC experiment selected as an Astromag investigation on Space Station Freedom. The study focused on Science Objectives and Science Requirement, Accommodation on both the STS and the Astromag facility, Data extraction techniques and Background Studies. The detectors are emulsion chambers which will be exposed for approximately 90 days and then recovered from orbit for subsequent processing and analysis in the laboratory. Such a technique is the only means to obtain information on the ultrahigh energy cosmic rays and their nuclear interactions. The SCIN/MAGIC investigation can supply unique data in relatively unexplored energy region and address many of the fundamental questions in particle astrophysics.

  3. 1H magic-angle spinning NMR evolves as a powerful new tool for membrane proteins

    NASA Astrophysics Data System (ADS)

    Schubeis, Tobias; Le Marchand, Tanguy; Andreas, Loren B.; Pintacuda, Guido

    2018-02-01

    Building on a decade of continuous advances of the community, the recent development of very fast (60 kHz and above) magic-angle spinning (MAS) probes has revolutionised the field of solid-state NMR. This new spinning regime reduces the 1H-1H dipolar couplings, so that direct detection of the larger magnetic moment available from 1H is now possible at high resolution, not only in deuterated molecules but also in fully-protonated substrates. Such capabilities allow rapid "fingerprinting" of samples with a ten-fold reduction of the required sample amounts with respect to conventional approaches, and permit extensive, robust and expeditious assignment of small-to-medium sized proteins (up to ca. 300 residues), and the determination of inter-nuclear proximities, relative orientations of secondary structural elements, protein-cofactor interactions, local and global dynamics. Fast MAS and 1H detection techniques have nowadays been shown to be applicable to membrane-bound systems. This paper reviews the strategies underlying this recent leap forward in sensitivity and resolution, describing its potential for the detailed characterization of membrane proteins.

  4. Novel NMR tools to study structure and dynamics of biomembranes.

    PubMed

    Gawrisch, Klaus; Eldho, Nadukkudy V; Polozov, Ivan V

    2002-06-01

    Nuclear magnetic resonance (NMR) studies on biomembranes have benefited greatly from introduction of magic angle spinning (MAS) NMR techniques. Improvements in MAS probe technology, combined with the higher magnetic field strength of modern instruments, enables almost liquid-like resolution of lipid resonances. The cross-relaxation rates measured by nuclear Overhauser enhancement spectroscopy (NOESY) provide new insights into conformation and dynamics of lipids with atomic-scale resolution. The data reflect the tremendous motional disorder in the lipid matrix. Transfer of magnetization by spin diffusion along the proton network of lipids is of secondary relevance, even at a long NOESY mixing time of 300 ms. MAS experiments with re-coupling of anisotropic interactions, like the 13C-(1)H dipolar couplings, benefit from the excellent resolution of 13C shifts that enables assignment of the couplings to specific carbon atoms. The traditional 2H NMR experiments on deuterated lipids have higher sensitivity when conducted on oriented samples at higher magnetic field strength. A very large number of NMR parameters from lipid bilayers is now accessible, providing information about conformation and dynamics for every lipid segment. The NMR methods have the sensitivity and resolution to study lipid-protein interaction, lateral lipid organization, and the location of solvents and drugs in the lipid matrix.

  5. Measurement of Atmospheric Pressure Air Plasma via Pulsed Electron Beam and Sustaining Electric Field

    DTIC Science & Technology

    2007-08-29

    cell plasma code ( MAGIC ) and an air-chemistry code are used to quantify beam propagation through an electron-beam transmission window into air and the...to generate and maintain plasma in air on the timescale of 1 ms. 15. SUBJECT TERMS Air Chemistry, Air Plasma, MAGIC Modeling, Plasma, Power, Test-Cell...Microwave diagnostics quantify electron number density and optical diagnostics quantify ozone production. A particle in cell plasma code ( MAGIC ) and an

  6. Experimental magic state distillation for fault-tolerant quantum computing.

    PubMed

    Souza, Alexandre M; Zhang, Jingfu; Ryan, Colm A; Laflamme, Raymond

    2011-01-25

    Any physical quantum device for quantum information processing (QIP) is subject to errors in implementation. In order to be reliable and efficient, quantum computers will need error-correcting or error-avoiding methods. Fault-tolerance achieved through quantum error correction will be an integral part of quantum computers. Of the many methods that have been discovered to implement it, a highly successful approach has been to use transversal gates and specific initial states. A critical element for its implementation is the availability of high-fidelity initial states, such as |0〉 and the 'magic state'. Here, we report an experiment, performed in a nuclear magnetic resonance (NMR) quantum processor, showing sufficient quantum control to improve the fidelity of imperfect initial magic states by distilling five of them into one with higher fidelity.

  7. A cusp electron gun for millimeter wave gyrodevices

    NASA Astrophysics Data System (ADS)

    Donaldson, C. R.; He, W.; Cross, A. W.; Li, F.; Phelps, A. D. R.; Zhang, L.; Ronald, K.; Robertson, C. W.; Whyte, C. G.; Young, A. R.

    2010-04-01

    The experimental results of a thermionic cusp electron gun, to drive millimeter and submillimeter wave harmonic gyrodevices, are reported in this paper. Using a "smooth" magnetic field reversal formed by two coils this gun generated an annular-shaped, axis-encircling electron beam with 1.5 A current, and an adjustable velocity ratio α of up to 1.56 at a beam voltage of 40 kV. The beam cross-sectional shape and transported beam current were measured by a witness plate technique and Faraday cup, respectively. These measured results were found to be in excellent agreement with the simulated results using the three-dimensional code MAGIC.

  8. Structural Insights into Bound Water in Crystalline Amino Acids: Experimental and Theoretical (17)O NMR.

    PubMed

    Michaelis, Vladimir K; Keeler, Eric G; Ong, Ta-Chung; Craigen, Kimberley N; Penzel, Susanne; Wren, John E C; Kroeker, Scott; Griffin, Robert G

    2015-06-25

    We demonstrate here that the (17)O NMR properties of bound water in a series of amino acids and dipeptides can be determined with a combination of nonspinning and magic-angle spinning experiments using a range of magnetic field strengths from 9.4 to 21.1 T. Furthermore, we propose a (17)O chemical shift fingerprint region for bound water molecules in biological solids that is well outside the previously determined ranges for carbonyl, carboxylic, and hydroxyl oxygens, thereby offering the ability to resolve multiple (17)O environments using rapid one-dimensional NMR techniques. Finally, we compare our experimental data against quantum chemical calculations using GIPAW and hybrid-DFT, finding intriguing discrepancies between the electric field gradients calculated from structures determined by X-ray and neutron diffraction.

  9. Magic bases, metric ansaetze and generalized graph theories in the Virasoro master equation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Halpern, M.B.; Obers, N.A.

    1991-11-15

    The authors define a class of magic Lie group bases in which the Virasoro master equation admits a class of simple metric ansaetze (g{sub metric}), whose structure is visible in the high-level expansion. When a magic basis is real on compact g, the corresponding g{sub metric} is a large system of unitary, generically irrational conformal field theories. Examples in this class include the graph-theory ansatz SO(n){sub diag} in the Cartesian basis of So(n) and the ansatz SU(n){sub metric} in the Pauli-like basis of SU(n). A new phenomenon is observed in the high-level comparison of SU(n){sub metric}: Due to the trigonometricmore » structure constants of the Pauli-like basis, irrational central charge is clearly visible at finite order of the expansion. They also define the sine-area graphs of SU(n), which label the conformal field theories of SU(n){sub metric} and note that, in a similar fashion, each magic basis of g defines a generalize graph theory on g which labels the conformal field theories of g{sub metric}.« less

  10. Theory for cross effect dynamic nuclear polarization under magic-angle spinning in solid state nuclear magnetic resonance: the importance of level crossings.

    PubMed

    Thurber, Kent R; Tycko, Robert

    2012-08-28

    We present theoretical calculations of dynamic nuclear polarization (DNP) due to the cross effect in nuclear magnetic resonance under magic-angle spinning (MAS). Using a three-spin model (two electrons and one nucleus), cross effect DNP with MAS for electron spins with a large g-anisotropy can be seen as a series of spin transitions at avoided crossings of the energy levels, with varying degrees of adiabaticity. If the electron spin-lattice relaxation time T(1e) is large relative to the MAS rotation period, the cross effect can happen as two separate events: (i) partial saturation of one electron spin by the applied microwaves as one electron spin resonance (ESR) frequency crosses the microwave frequency and (ii) flip of all three spins, when the difference of the two ESR frequencies crosses the nuclear frequency, which transfers polarization to the nuclear spin if the two electron spins have different polarizations. In addition, adiabatic level crossings at which the two ESR frequencies become equal serve to maintain non-uniform saturation across the ESR line. We present analytical results based on the Landau-Zener theory of adiabatic transitions, as well as numerical quantum mechanical calculations for the evolution of the time-dependent three-spin system. These calculations provide insight into the dependence of cross effect DNP on various experimental parameters, including MAS frequency, microwave field strength, spin relaxation rates, hyperfine and electron-electron dipole coupling strengths, and the nature of the biradical dopants.

  11. Making the MagIC (Magnetics Information Consortium) Web Application Accessible to New Users and Useful to Experts

    NASA Astrophysics Data System (ADS)

    Minnett, R.; Koppers, A.; Jarboe, N.; Tauxe, L.; Constable, C.; Jonestrask, L.

    2017-12-01

    Challenges are faced by both new and experienced users interested in contributing their data to community repositories, in data discovery, or engaged in potentially transformative science. The Magnetics Information Consortium (https://earthref.org/MagIC) has recently simplified its data model and developed a new containerized web application to reduce the friction in contributing, exploring, and combining valuable and complex datasets for the paleo-, geo-, and rock magnetic scientific community. The new data model more closely reflects the hierarchical workflow in paleomagnetic experiments to enable adequate annotation of scientific results and ensure reproducibility. The new open-source (https://github.com/earthref/MagIC) application includes an upload tool that is integrated with the data model to provide early data validation feedback and ease the friction of contributing and updating datasets. The search interface provides a powerful full text search of contributions indexed by ElasticSearch and a wide array of filters, including specific geographic and geological timescale filtering, to support both novice users exploring the database and experts interested in compiling new datasets with specific criteria across thousands of studies and millions of measurements. The datasets are not large, but they are complex, with many results from evolving experimental and analytical approaches. These data are also extremely valuable due to the cost in collecting or creating physical samples and the, often, destructive nature of the experiments. MagIC is heavily invested in encouraging young scientists as well as established labs to cultivate workflows that facilitate contributing their data in a consistent format. This eLightning presentation includes a live demonstration of the MagIC web application, developed as a configurable container hosting an isomorphic Meteor JavaScript application, MongoDB database, and ElasticSearch search engine. Visitors can explore the MagIC Database through maps and image or plot galleries or search and filter the raw measurements and their derived hierarchy of analytical interpretations.

  12. Dissipative Quantum Mechanics and Kondo-Like Impurities on Noncommutative Two-Tori

    NASA Astrophysics Data System (ADS)

    Iacomino, Patrizia; Marotta, Vincenzo; Naddeo, Adele

    In a recent paper, by exploiting the notion of Morita equivalence for field theories on noncommutative tori and choosing rational values of the noncommutativity parameter θ (in appropriate units), a general one-to-one correspondence between the m-reduced conformal field theory (CFT) describing a quantum Hall fluid (QHF) at paired states fillings1,2 ν = (m)/(pm+2) and an Abelian noncommutative field theory (NCFT) has been established.3 That allowed us to add new evidence to the relationship between noncommutativity and quantum Hall fluids.4 On the other hand, the m-reduced CFT is equivalent to a system of two massless scalar bosons with a magnetic boundary interaction as introduced in Ref. 5, at the so-called "magic" points. We are then able to describe, within such a framework, the dissipative quantum mechanics of a particle confined to a plane and subject to an external magnetic field normal to it. Here we develop such a point of view by focusing on the case m=2 which corresponds to a quantum Hall bilayer. The key role of a localized impurity which couples the two layers is emphasized and the effect of noncommutativity in terms of generalized magnetic translations (GMT) is fully exploited. As a result, general GMT operators are introduced, in the form of a tensor product, which act on the QHF and defect space respectively, and a comprehensive study of their rich structure is performed.

  13. Tunable magic wavelengths for trapping with focused Laguerre-Gaussian beams

    NASA Astrophysics Data System (ADS)

    Bhowmik, Anal; Dutta, Narendra Nath; Majumder, Sonjoy

    2018-02-01

    We present in this paper a theory of dynamic polarizability for an atomic state due to an external field of nonparaxial Laguerre-Gaussian (LG) beam using the sum-over-states technique. A highly correlated relativistic coupled-cluster theory is used to evaluate the most important and correlation-sensitive parts of the sum. The theory is applied on Sr+ to determine the magic wavelengths for 5 s1 /2→4 d3 /2,4 d5 /2 transitions. Results show the variation of magic wavelengths with the choice of orbital and spin angular momenta of the incident LG beam. Also, the tunability of the magic wavelengths is studied by using the focusing angle of the LG beam and its efficiency in the near-infrared region is observed. Evaluations of the wide spectrum of magic wavelengths from infrared to ultraviolet have substantial importance to experimentalists for carrying out high-precision measurements in fundamental physics. These magic wavelengths can be used to confine the atom or ion at the dark central node or at the high-intensity ring of the LG beam.

  14. A field-emission based vacuum device for the generation of THz waves

    NASA Astrophysics Data System (ADS)

    Lin, Ming-Chieh

    2005-03-01

    Terahertz waves have been used to characterize the electronic, vibrational and compositional properties of solid, liquid and gas phase materials during the past decade. More and more applications in imaging science and technology call for the well development of THz wave sources. Amplification and generation of a high frequency electromagnetic wave are a common interest of field emission based devices. In the present work, we propose a vacuum electronic device based on field emission mechanism for the generation of THz waves. To verify our thinking and designs, the cold tests and the hot tests have been studied via the simulation tools, SUPERFISH and MAGIC. In the hot tests, two types of electron emission mechanisms are considered. One is the field emission and the other is the explosive emission. The preliminary design of the device is carried out and tested by the numerical simulations. The simulation results show that an electronic efficiency up to 4% can be achieved without employing any magnetic circuits.

  15. Magnetic Anastomosis for Glycemic Insulin Control (MAGIC): A Pilot Study of Minimally Invasive (Endoscopic/Laparoscopic) Side-to-Side Duodeno-Distal Ileal Anastomosis in Pigs

    DTIC Science & Technology

    2013-10-08

    Compression Anastomosis Corrects Insulin Resistance in Diabetic Pigs. PURPOSE: Bariatric surgery corrects insulin resistance independent of weight loss...magnets (48% ± 3 vs 18% ± 14). No anastomotic leaks or strictures were observed in any animals. All animals took liquids on the day of surgery and were

  16. A nuclear magnetic resonance spectrometer concept for hermetically sealed magic angle spinning investigations on highly toxic, radiotoxic, or air sensitive materials.

    PubMed

    Martel, L; Somers, J; Berkmann, C; Koepp, F; Rothermel, A; Pauvert, O; Selfslag, C; Farnan, I

    2013-05-01

    A concept to integrate a commercial high-resolution, magic angle spinning nuclear magnetic resonance (MAS-NMR) probe capable of very rapid rotation rates (70 kHz) in a hermetically sealed enclosure for the study of highly radiotoxic materials has been developed and successfully demonstrated. The concept centres on a conventional wide bore (89 mm) solid-state NMR magnet operating with industry standard 54 mm diameter probes designed for narrow bore magnets. Rotor insertion and probe tuning take place within a hermetically enclosed glovebox, which extends into the bore of the magnet, in the space between the probe and the magnet shim system. Oxygen-17 MAS-NMR measurements demonstrate the possibility of obtaining high quality spectra from small sample masses (~10 mg) of highly radiotoxic material and the need for high spinning speeds to improve the spectral resolution when working with actinides. The large paramagnetic susceptibility arising from actinide paramagnetism in (Th(1-x)U(x))O2 solid solutions gives rise to extensive spinning sidebands and poor resolution at 15 kHz, which is dramatically improved at 55 kHz. The first (17)O MAS-NMR measurements on NpO(2+x) samples spinning at 55 kHz are also reported. The glovebox approach developed here for radiotoxic materials can be easily adapted to work with other hazardous or even air sensitive materials.

  17. g-factor calculations from the generalized seniority approach

    NASA Astrophysics Data System (ADS)

    Maheshwari, Bhoomika; Jain, Ashok Kumar

    2018-05-01

    The generalized seniority approach proposed by us to understand the B(E1)/B(E2)/B(E3) properties of semi-magic nuclei has been widely successful in the explanation of the same and has led to an expansion in the scope of seniority isomers. In the present paper, we apply the generalized seniority scheme to understand the behavior of g-factors in semi-magic nuclei. We find that the magnetic moment and the gfactors do show a particle number independent behavior as expected and the understanding is consistent with the explanation of transition probabilities.

  18. High-pressure, high-temperature magic angle spinning nuclear magnetic resonance devices and processes for making and using same

    DOEpatents

    Hu, Jian Zhi; Hu, Mary Y.; Townsend, Mark R.; Lercher, Johannes A.; Peden, Charles H. F.

    2015-10-06

    Re-usable ceramic magic angle spinning (MAS) NMR rotors constructed of high-mechanic strength ceramics are detailed that include a sample compartment that maintains high pressures up to at least about 200 atmospheres (atm) and high temperatures up to about least about 300.degree. C. during operation. The rotor designs minimize pressure losses stemming from penetration over an extended period of time. The present invention makes possible a variety of in-situ high pressure, high temperature MAS NMR experiments not previously achieved in the prior art.

  19. Magic Universe - The Oxford Guide to Modern Science

    NASA Astrophysics Data System (ADS)

    Calder, Nigel

    2003-11-01

    As a prolific author, BBC commentator, and magazine editor, Nigel Calder has spent a lifetime spotting and explaining the big discoveries in all branches of science. In Magic Universe , he draws on his vast experience to offer readers a lively, far-reaching look at modern science in all its glory, shedding light on the latest ideas in physics, biology, chemistry, medicine, astronomy, and many other fields. What is truly magical about Magic Universe is Calder's incredible breadth. Migrating birds, light sensors in the human eye, black holes, antimatter, buckyballs and nanotubes--with exhilarating sweep, Calder can range from the strings of a piano to the superstrings of modern physics, from Pythagoras's theory of musical pitch to the most recent ideas about atoms and gravity and a ten-dimensional universe--all in one essay. The great virtue of this wide-ranging style--besides its liveliness and versatility--is that it allows Calder to illuminate how the modern sciences intermingle and cross-fertilize one another. Indeed, whether discussing astronauts or handedness or dinosaurs, Calder manages to tease out hidden connections between disparate fields of study. What is most wondrous about the "magic universe" is that one can begin with stellar dust and finish with life itself. Drawing on interviews with more than 200 researchers, from graduate students to Nobel prize-winners, Magic Universe takes us on a high-spirited tour through the halls of science, one that will enthrall everyone interested in science, whether a young researcher in a high-tech lab or an amateur buff sitting in the comfort of an armchair.

  20. Towards real-time metabolic profiling of a biopsy specimen during a surgical operation by 1H high resolution magic angle spinning nuclear magnetic resonance: a case report.

    PubMed

    Piotto, Martial; Moussallieh, François-Marie; Neuville, Agnès; Bellocq, Jean-Pierre; Elbayed, Karim; Namer, Izzie Jacques

    2012-01-18

    Providing information on cancerous tissue samples during a surgical operation can help surgeons delineate the limits of a tumoral invasion more reliably. Here, we describe the use of metabolic profiling of a colon biopsy specimen by high resolution magic angle spinning nuclear magnetic resonance spectroscopy to evaluate tumoral invasion during a simulated surgical operation. Biopsy specimens (n = 9) originating from the excised right colon of a 66-year-old Caucasian women with an adenocarcinoma were automatically analyzed using a previously built statistical model. Metabolic profiling results were in full agreement with those of a histopathological analysis. The time-response of the technique is sufficiently fast for it to be used effectively during a real operation (17 min/sample). Metabolic profiling has the potential to become a method to rapidly characterize cancerous biopsies in the operation theater.

  1. Crocus sativus Petals: Waste or Valuable Resource? The Answer of High-Resolution and High-Resolution Magic Angle Spinning Nuclear Magnetic Resonance.

    PubMed

    Righi, Valeria; Parenti, Francesca; Tugnoli, Vitaliano; Schenetti, Luisa; Mucci, Adele

    2015-09-30

    Intact Crocus sativus petals were studied for the first time by high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy, revealing the presence of kinsenoside (2) and goodyeroside A (3), together with 3-hydroxy-γ-butyrolactone (4). These findings were confirmed by HR-NMR analysis of the ethanol extract of fresh petals and showed that, even though carried out rapidly, partial hydrolysis of glucopyranosyloxybutanolides occurs during extraction. On the other hand, kaempferol 3-O-sophoroside (1), which is "NMR-silent" in intact petals, is present in extracts. These results suggest to evaluate the utilization of saffron petals for phytopharmaceutical and nutraceutical purposes to exploit a waste product of massive production of commercial saffron and point to the application of HR-MAS NMR for monitoring bioactive compounds directly on intact petals, avoiding the extraction procedure and the consequent hydrolysis reaction.

  2. Marine ARM GPCI Investigation of Clouds (MAGIC) Field Campaign Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lewis, Ernie R.

    The Marine ARM GPCI Investigation of Clouds (MAGIC) field campaign, which deployed the second ARM Mobile Facility (AMF2) aboard the Horizon Lines cargo container ship Spirit as it ran its regular route between Los Angeles, California and Honolulu, Hawaii, measured properties of clouds and precipitation, aerosols, radiation, and atmospheric, meteorological, and oceanic conditions with the goal of obtaining statistics of these properties to achieve better understanding of the transition between stratocumulus and cumulus cloud regimes that occur in that region. This Sc-Cu transition is poorly represented in models, and a major reason for this is the lack of high-quality andmore » comprehensive data that can be used to constrain, validate, and improve model representation of the transition. MAGIC consisted of 20 round trips between Los Angeles and Honolulu, and thus over three dozen transects through the transition, totaling nearly 200 days at sea between September, 2012 and October, 2013. During this time MAGIC collected a unique and unprecedented data set, including more than 550 successful radiosonde launches. An Intensive Observational Period (IOP) occurred in July, 2013 during which more detailed measurements of the atmospheric structure were made. MAGIC was very successful in its operations and overcame numerous logistical and technological challenges, clearly demonstrating the feasibility of a marine AMF2 deployment and the ability to make accurate measurements of clouds and precipitation, aerosols, and radiation while at sea.« less

  3. Reviews

    NASA Astrophysics Data System (ADS)

    2004-01-01

    BOOK REVIEWS (99) Complete A-Z Physics Handbook Science Magic in the Kitchen The Science of Cooking Science Experiments You Can Eat WEB WATCH (101) These journal themes are pasta joke Microwave oven Web links CD REVIEW (104) Electricity and Magnetism, KS3 Big Science Comics

  4. Spatial reorientation experiments for NMR of solids and partially oriented liquids.

    PubMed

    Martin, Rachel W; Kelly, John E; Collier, Kelsey A

    2015-11-01

    Motional reorientation experiments are extensions of Magic Angle Spinning (MAS) where the rotor axis is changed in order to average out, reintroduce, or scale anisotropic interactions (e.g. dipolar couplings, quadrupolar interactions or chemical shift anisotropies). This review focuses on Variable Angle Spinning (VAS), Switched Angle Spinning (SAS), and Dynamic Angle Spinning (DAS), all of which involve spinning at two or more different angles sequentially, either in successive experiments or during a multidimensional experiment. In all of these experiments, anisotropic terms in the Hamiltonian are scaled by changing the orientation of the spinning sample relative to the static magnetic field. These experiments vary in experimental complexity and instrumentation requirements. In VAS, many one-dimensional spectra are collected as a function of spinning angle. In SAS, dipolar couplings and/or chemical shift anisotropies are reintroduced by switching the sample between two different angles, often 0° or 90° and the magic angle, yielding a two-dimensional isotropic-anisotropic correlation spectrum. Dynamic Angle Spinning (DAS) is a related experiment that is used to simultaneously average out the first- and second-order quadrupolar interactions, which cannot be accomplished by spinning at any unique rotor angle in physical space. Although motional reorientation experiments generally require specialized instrumentation and data analysis schemes, some are accessible with only minor modification of standard MAS probes. In this review, the mechanics of each type of experiment are described, with representative examples. Current and historical probe and coil designs are discussed from the standpoint of how each one accomplishes the particular objectives of the experiment(s) it was designed to perform. Finally, applications to inorganic materials and liquid crystals, which present very different experimental challenges, are discussed. The review concludes with perspectives on how motional reorientation experiments can be applied to current problems in chemistry, molecular biology, and materials science, given the many advances in high-field NMR magnets, fast spinning, and sample preparation realized in recent years. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Hypothalamic metabolic compartmentation during appetite regulation as revealed by magnetic resonance imaging and spectroscopy methods

    PubMed Central

    Lizarbe, Blanca; Benitez, Ania; Peláez Brioso, Gerardo A.; Sánchez-Montañés, Manuel; López-Larrubia, Pilar; Ballesteros, Paloma; Cerdán, Sebastián

    2013-01-01

    We review the role of neuroglial compartmentation and transcellular neurotransmitter cycling during hypothalamic appetite regulation as detected by Magnetic Resonance Imaging (MRI) and Spectroscopy (MRS) methods. We address first the neurochemical basis of neuroendocrine regulation in the hypothalamus and the orexigenic and anorexigenic feed-back loops that control appetite. Then we examine the main MRI and MRS strategies that have been used to investigate appetite regulation. Manganese-enhanced magnetic resonance imaging (MEMRI), Blood oxygenation level-dependent contrast (BOLD), and Diffusion-weighted magnetic resonance imaging (DWI) have revealed Mn2+ accumulations, augmented oxygen consumptions, and astrocytic swelling in the hypothalamus under fasting conditions, respectively. High field 1H magnetic resonance in vivo, showed increased hypothalamic myo-inositol concentrations as compared to other cerebral structures. 1H and 13C high resolution magic angle spinning (HRMAS) revealed increased neuroglial oxidative and glycolytic metabolism, as well as increased hypothalamic glutamatergic and GABAergic neurotransmissions under orexigenic stimulation. We propose here an integrative interpretation of all these findings suggesting that the neuroendocrine regulation of appetite is supported by important ionic and metabolic transcellular fluxes which begin at the tripartite orexigenic clefts and become extended spatially in the hypothalamus through astrocytic networks becoming eventually MRI and MRS detectable. PMID:23781199

  6. Team Teaching an Interdisciplinary First-Year Seminar on Magic, Religion, and the Origins of Science: A "Pieces-to-Picture" Approach

    ERIC Educational Resources Information Center

    Nungsari, Melati; Dedrick, Maia; Patel, Shaily

    2017-01-01

    Interdisciplinary teaching has been advocated as a means to foster cooperation between traditionally separate fields and broaden students' perspectives in the classroom. We explored the pedagogical difficulties of interdisciplinary team teaching through a first-year seminar in magic, religion, and the origins of science. Although many accounts in…

  7. Magnetic resonance metabolomics of intact tissue: a biotechnological tool in cancer diagnostics and treatment evaluation.

    PubMed

    Bathen, Tone F; Sitter, Beathe; Sjøbakk, Torill E; Tessem, May-Britt; Gribbestad, Ingrid S

    2010-09-01

    Personalized medicine is increasingly important in cancer treatment for its role in staging and its potential to improve stratification of patients. Different types of molecules, genes, proteins, and metabolites are being extensively explored as potential biomarkers. This review discusses the major findings and potential of tissue metabolites determined by high-resolution magic angle spinning magnetic resonance spectroscopy for cancer detection, characterization, and treatment monitoring.

  8. Rock Magnetism: Successes and Mysteries

    NASA Astrophysics Data System (ADS)

    Dunlop, D. J.

    2011-12-01

    Louis Néel once proposed making ships "invisible" (i.e., magnetically undetectable) by giving them a permanent or remanent magnetism that would cancel the signal induced by the Earth's magnetic field. Like much of rock magnetism, this borders on the magical. Rocks possess a magnetic memory that verges on the phenomenal. An adequate magnetic lifetime for your credit card is until its expiry date and one must avoid exposure to magnetic fields and heat. But a rock's magnetic memory is forever, and the recipe for that durability includes, for igneous and metamorphic rocks, exposure to ancient fields while hot - near the Curie temperature in fact. The thermal remanent magnetism (TRM) thus produced is largely immune to later field changes at lower temperatures although luckily a fraction - a partial TRM overprint - does record later heating events, e.g., burial during major orogenies. When we lift the veil and look closely, on a microscale or nanoscale, it is perplexing to understand why paleomagnetism works so well when rocks seemingly contain so few of Néel's ideal recorders: single-domain grains with tightly coupled atomic spins. In larger grains with multiple domains, the walls between neighbouring domains move readily, like dislocations in crystals, enlarging some domains at the expense of others. This mutability makes any magnetic memory of multi-domain grains suspect. But around the threshold between single-domain and multi-domain structures - a specific grain size that varies widely from one magnetic mineral to another - there are recent predictions and observations of novel structures, including linked magnetic moments of nearby grains and interfacial moments of exsolved phases, that could go some way towards explaining why single-domain-like behaviour is so widespread. Many magnetic properties show an almost continuous variation with grain size, quite unlike the expected discontinuity at the single-domain threshold. Among these is initial susceptibility which governs a rock's induced response to weak fields like the Earth's. In particular, the Hopkinson peak in susceptibility near the Curie temperature - a potential source of "missing magnetism" in the deep lithosphere - increases steadily over at least a decade of decreasing grain size in magnetite. Single-domain recorders, in addition to their strong and long-lasting memory, have the property of TRM additivity and independence. This makes possible the Thellier method of determining paleofield intensity, a much more demanding undertaking than tracking paleomagnetic field directions, in which the ancient magnetic moment is gradually replaced by a set of partial TRMs produced in a known laboratory field. Partial TRMs produced in nature by heating during deep burial are also additive and independent. The temperature at which these overprints are removed in the laboratory yields - after correction for the very different natural and laboratory heating times - the burial temperature. This is the basis of magnetic paleothermometry. The interplay of time and temperature in TRM when combined with thermal history models provides estimates of when the global magnetic field of a planet, e.g., Mars, was born and died. But the grand conclusions so important to geophysics rest ultimately on the fidelity of the microscopic recorders in rocks and here, despite many advances, our understanding is still a work in progress.

  9. On the application of magic echo cycles for quadrupolar echo spectroscopy of spin-1 nuclei.

    PubMed

    Mananga, E S; Roopchand, R; Rumala, Y S; Boutis, G S

    2007-03-01

    Magic echo cycles are introduced for performing quadrupolar echo spectroscopy of spin-1 nuclei. An analysis is performed via average Hamiltonian theory showing that the evolution under chemical shift or static field inhomogeneity can be refocused simultaneously with the quadrupolar interaction using these cycles. Due to the higher convergence in the Magnus expansion, with sufficient RF power, magic echo based quadrupolar echo spectroscopy outperforms the conventional two pulse quadrupolar echo in signal to noise. Experiments highlighting a signal to noise enhancement over the entire bandwidth of the quadrupolar pattern of a powdered sample of deuterated polyethelene are shown.

  10. A cut-off in the TeV gamma-ray spectrum of the SNR Cassiopeia A

    NASA Astrophysics Data System (ADS)

    Ahnen, M. L.; Ansoldi, S.; Antonelli, L. A.; Arcaro, C.; Babić, A.; Banerjee, B.; Bangale, P.; Barres de Almeida, U.; Barrio, J. A.; Becerra González, J.; Bednarek, W.; Bernardini, E.; Berti, A.; Bhattacharyya, W.; Biasuzzi, B.; Biland, A.; Blanch, O.; Bonnefoy, S.; Bonnoli, G.; Carosi, R.; Carosi, A.; Chatterjee, A.; Colak, M.; Colin, P.; Colombo, E.; Contreras, J. L.; Cortina, J.; Covino, S.; Cumani, P.; Da Vela, P.; Dazzi, F.; De Angelis, A.; De Lotto, B.; de Oña Wilhelmi, E.; Di Pierro, F.; Doert, M.; Domínguez, A.; Dominis Prester, D.; Dorner, D.; Doro, M.; Einecke, S.; Eisenacher Glawion, D.; Elsaesser, D.; Engelkemeier, M.; Fallah Ramazani, V.; Fernández-Barral, A.; Fidalgo, D.; Fonseca, M. V.; Font, L.; Fruck, C.; Galindo, D.; García López, R. J.; Garczarczyk, M.; Gaug, M.; Giammaria, P.; Godinović, N.; Gora, D.; Guberman, D.; Hadasch, D.; Hahn, A.; Hassan, T.; Hayashida, M.; Herrera, J.; Hose, J.; Hrupec, D.; Inada, T.; Ishio, K.; Konno, Y.; Kubo, H.; Kushida, J.; Kuveždić, D.; Lelas, D.; Lindfors, E.; Lombardi, S.; Longo, F.; López, M.; Maggio, C.; Majumdar, P.; Makariev, M.; Maneva, G.; Manganaro, M.; Mannheim, K.; Maraschi, L.; Mariotti, M.; Martínez, M.; Mazin, D.; Menzel, U.; Minev, M.; Mirzoyan, R.; Moralejo, A.; Moreno, V.; Moretti, E.; Neustroev, V.; Niedzwiecki, A.; Nievas Rosillo, M.; Nilsson, K.; Ninci, D.; Nishijima, K.; Noda, K.; Nogués, L.; Paiano, S.; Palacio, J.; Paneque, D.; Paoletti, R.; Paredes, J. M.; Pedaletti, G.; Peresano, M.; Perri, L.; Persic, M.; Prada Moroni, P. G.; Prandini, E.; Puljak, I.; Garcia, J. R.; Reichardt, I.; Rhode, W.; Ribó, M.; Rico, J.; Righi, C.; Saito, T.; Satalecka, K.; Schroeder, S.; Schweizer, T.; Shore, S. N.; Sitarek, J.; Šnidarić, I.; Sobczynska, D.; Stamerra, A.; Strzys, M.; Surić, T.; Takalo, L.; Tavecchio, F.; Temnikov, P.; Terzić, T.; Tescaro, D.; Teshima, M.; Torres-Albà, N.; Treves, A.; Vanzo, G.; Vazquez Acosta, M.; Vovk, I.; Ward, J. E.; Will, M.; Zarić, D.

    2017-12-01

    It is widely believed that the bulk of the Galactic cosmic rays is accelerated in supernova remnants (SNRs). However, no observational evidence of the presence of particles of PeV energies in SNRs has yet been found. The young historical SNR Cassiopeia A (Cas A) appears as one of the best candidates to study acceleration processes. Between 2014 December and 2016 October, we observed Cas A with the MAGIC telescopes, accumulating 158 h of good quality data. We derived the spectrum of the source from 100 GeV to 10 TeV. We also analysed ∼8 yr of Fermi-LAT to obtain the spectral shape between 60 MeV and 500 GeV. The spectra measured by the LAT and MAGIC telescopes are compatible within the errors and show a clear turn-off (4.6σ) at the highest energies, which can be described with an exponential cut-off at E_c = 3.5(^{+1.6}_{-1.0})_{stat} (^{+0.8}_{-0.9})_{sys} TeV. The gamma-ray emission from 60 MeV to 10 TeV can be attributed to a population of high-energy protons with a spectral index of ∼2.2 and an energy cut-off at ∼10 TeV. This result indicates that Cas A is not contributing to the high energy (∼PeV) cosmic ray sea in a significant manner at the present moment. A one-zone leptonic model fails to reproduce by itself the multiwavelength spectral energy distribution. Besides, if a non-negligible fraction of the flux seen by MAGIC is produced by leptons, the radiation should be emitted in a region with a low magnetic field (B⪅180 μG) like in the reverse shock.

  11. 17O NMR Investigation of Water Structure and Dynamics

    PubMed Central

    Keeler, Eric G.; Michaelis, Vladimir K.; Griffin, Robert G.

    2017-01-01

    The structure and dynamics of the bound water in barium chlorate monohydrate were studied with 17O nuclear magnetic resonance (NMR) spectroscopy in samples that are stationary and spinning at the magic-angle in magnetic fields ranging from 14.1 to 21.1 T. 17O NMR parameters of the water were determined, and the effects of torsional oscillations of the water molecule on the 17O quadrupolar coupling constant (CQ) were delineated with variable temperature MAS NMR. With decreasing temperature and reduction of the librational motion, we observe an increase in the experimentally measured CQ explaining the discrepancy between experiments and predictions from density functional theory. In addition, at low temperatures and in the absence of 1H decoupling, we observe a well-resolved 1H–17O dipole splitting in the spectra, which provides information on the structure of the H2O molecule. The splitting arises because of the homogeneous nature of the coupling between the two 1H–17O dipoles and the 1H–1H dipole. PMID:27454747

  12. Natural abundance (25)Mg solid-state NMR of mg oxyanion systems: a combined experimental and computational study.

    PubMed

    Cahill, Lindsay S; Hanna, John V; Wong, Alan; Freitas, Jair C C; Yates, Jonathan R; Harris, Robin K; Smith, Mark E

    2009-09-28

    Solid-state (25)Mg magic angle spinning nuclear magnetic resonance (MAS NMR) data are reported from a range of organic and inorganic magnesium-oxyanion compounds at natural abundance. To constrain the determination of the NMR interaction parameters (delta(iso), chi(Q), eta(Q)) data have been collected at three external magnetic fields (11.7, 14.1 and 18.8 T). Corresponding NMR parameters have also been calculated by using density functional theory (DFT) methods using the GIPAW approach, with good correlations being established between experimental and calculated values of both chi(Q) and delta(iso). These correlations demonstrate that the (25)Mg NMR parameters are very sensitive to the structure, with small changes in the local Mg(2+) environment and the overall hydration state profoundly affecting the observed spectra. The observations suggest that (25)Mg NMR spectroscopy is a potentially potent probe for addressing some key problems in inorganic materials and of metal centres in biologically relevant molecules.

  13. Solid-state dynamic nuclear polarization at 263 GHz: spectrometer design and experimental results†

    PubMed Central

    Rosay, Melanie; Tometich, Leo; Pawsey, Shane; Bader, Reto; Schauwecker, Robert; Blank, Monica; Borchard, Philipp M.; Cauffman, Stephen R.; Felch, Kevin L.; Weber, Ralph T.; Temkin, Richard J.; Griffin, Robert G.; Maas, Werner E.

    2015-01-01

    Dynamic Nuclear Polarization (DNP) experiments transfer polarization from electron spins to nuclear spins with microwave irradiation of the electron spins for enhanced sensitivity in nuclear magnetic resonance (NMR) spectroscopy. Design and testing of a spectrometer for magic angle spinning (MAS) DNP experiments at 263 GHz microwave frequency, 400 MHz 1H frequency is described. Microwaves are generated by a novel continuous-wave gyrotron, transmitted to the NMR probe via a transmission line, and irradiated on a 3.2 mm rotor for MAS DNP experiments. DNP signal enhancements of up to 80 have been measured at 95 K on urea and proline in water–glycerol with the biradical polarizing agent TOTAPOL. We characterize the experimental parameters affecting the DNP efficiency: the magnetic field dependence, temperature dependence and polarization build-up times, microwave power dependence, sample heating effects, and spinning frequency dependence of the DNP signal enhancement. Stable system operation, including DNP performance, is also demonstrated over a 36 h period. PMID:20449524

  14. NMR longitudinal relaxation enhancement in metal halides by heteronuclear polarization exchange during magic-angle spinning

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shmyreva, Anna A.; Safdari, Majid; Furó, István

    2016-06-14

    Orders of magnitude decrease of {sup 207}Pb and {sup 199}Hg NMR longitudinal relaxation times T{sub 1} upon magic-angle-spinning (MAS) are observed and systematically investigated in solid lead and mercury halides MeX{sub 2} (Me = Pb, Hg and X = Cl, Br, I). In lead(II) halides, the most dramatic decrease of T{sub 1} relative to that in a static sample is in PbI{sub 2}, while it is smaller but still significant in PbBr{sub 2}, and not detectable in PbCl{sub 2}. The effect is magnetic-field dependent but independent of the spinning speed in the range 200–15 000 Hz. The observed relaxation enhancementmore » is explained by laboratory-frame heteronuclear polarization exchange due to crossing between energy levels of spin-1/2 metal nuclei and adjacent quadrupolar-spin halogen nuclei. The enhancement effect is also present in lead-containing organometal halide perovskites. Our results demonstrate that in affected samples, it is the relaxation data recorded under non-spinning conditions that characterize the local properties at the metal sites. A practical advantage of fast relaxation at slow MAS is that spectral shapes with orientational chemical shift anisotropy information well retained can be acquired within a shorter experimental time.« less

  15. The Ecological Classroom: The Magic and Mystery of Electricity.

    ERIC Educational Resources Information Center

    Cookman, Ed

    1993-01-01

    Ecological, interdisciplinary, and interconnected laboratory lessons focusing on magneticism: (1) producing electric power; (2) magnetics and magneticism; (3) electomagnetism (2 parts); and turbines (2 parts). Lessons, designed as precursor for students to make choices in electricity production, use a directed inquiry approach. (MCO)

  16. Towards real-time metabolic profiling of a biopsy specimen during a surgical operation by 1H high resolution magic angle spinning nuclear magnetic resonance: a case report

    PubMed Central

    2012-01-01

    Introduction Providing information on cancerous tissue samples during a surgical operation can help surgeons delineate the limits of a tumoral invasion more reliably. Here, we describe the use of metabolic profiling of a colon biopsy specimen by high resolution magic angle spinning nuclear magnetic resonance spectroscopy to evaluate tumoral invasion during a simulated surgical operation. Case presentation Biopsy specimens (n = 9) originating from the excised right colon of a 66-year-old Caucasian women with an adenocarcinoma were automatically analyzed using a previously built statistical model. Conclusions Metabolic profiling results were in full agreement with those of a histopathological analysis. The time-response of the technique is sufficiently fast for it to be used effectively during a real operation (17 min/sample). Metabolic profiling has the potential to become a method to rapidly characterize cancerous biopsies in the operation theater. PMID:22257563

  17. Physical Attraction: The Mysteries of Magnetism

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stohr, Joachim

    2004-12-14

    Most people have intuitive associations with the word 'magnetism' based on everyday life: refrigerator magnets, the compass, north and south poles, or someone's 'magnetic personality'. Few people, however, realize how complicated the phenomenon really is, how much research still deals with the topic today, and how much it penetrates our modern industrialized world - from electricity, wireless communication at the speed of light to magnetic sensors in cars and data storage in computers. Stohr's lecture will provide a glimpse at the magic and science behind magnetism: its long history, scientific breakthroughs in its understanding, and its use in our modernmore » society. In the process Stohr will show how research at SSRL/SLAC is addressing some of the forefront issues in magnetism research and technology today.« less

  18. High-Resolution Magic Angle Spinning Nuclear Magnetic Resonance of Intact Zebrafish Embryos Detects Metabolic Changes Following Exposure to Teratogenic Polymethoxyalkenes from Algae

    PubMed Central

    Roy, Upasana; Jaja-Chimedza, Asha; Sanchez, Kristel; Matysik, Joerg

    2016-01-01

    Abstract Techniques based on nuclear magnetic resonance (NMR) for imaging and chemical analyses of in vivo, or otherwise intact, biological systems are rapidly emerging and finding diverse applications within a wide range of fields. Very recently, several NMR-based techniques have been developed for the zebrafish as a model animal system. In the current study, the novel application of high-resolution magic angle spinning (HR-MAS) NMR is presented as a means of metabolic profiling of intact zebrafish embryos. Toward investigating the utility of HR-MAS NMR as a toxicological tool, these studies specifically examined metabolic changes of embryos exposed to polymethoxy-1-alkenes (PMAs)—a recently identified family of teratogenic compounds from freshwater algae—as emerging environmental contaminants. One-dimensional and two-dimensional HR-MAS NMR analyses were able to effectively identify and quantify diverse metabolites in early-stage (≤36 h postfertilization) embryos. Subsequent comparison of the metabolic profiles between PMA-exposed and control embryos identified several statistically significant metabolic changes associated with subacute exposure to the teratogen, including (1) elevated inositol as a recognized component of signaling pathways involved in embryo development; (2) increases in several metabolites, including inositol, phosphoryl choline, fatty acids, and cholesterol, which are associated with lipid composition of cell membranes; (3) concomitant increase in glucose and decrease in lactate; and (4) decreases in several biochemically related metabolites associated with central nervous system development and function, including γ-aminobutyric acid, glycine, glutamate, and glutamine. A potentially unifying model/hypothesis of PMA teratogenicity based on the data is presented. These findings, taken together, demonstrate that HR-MAS NMR is a promising tool for metabolic profiling in the zebrafish embryo, including toxicological applications. PMID:27348393

  19. Structure of Ancient Glass by 29 Si Magic Angle Spinning NMR Spectroscopy.

    PubMed

    Bradford, Henry; Ryder, Amy; Henderson, Julian; Titman, Jeremy J

    2018-05-23

    29 Si magic angle spinning (MAS) NMR spectroscopy has been applied for the first time to the structural analysis of ancient glass samples obtained from archaeological excavations. The results show that it is possible to establish the distribution of Si environments in ancient glass by 29 Si MAS NMR, so long as the concentrations of magnetic impurities, such as Mn and Fe oxides, are low. In general, good agreement has been obtained with compositions determined by means of electron probe microanalysis. In addition, the 29 Si MAS NMR data reveal structural differences between glasses manufactured at separate ancient sites. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Magic angle spinning nuclear magnetic resonance apparatus and process for high-resolution in situ investigations

    DOEpatents

    Hu, Jian Zhi; Sears, Jr., Jesse A.; Hoyt, David W.; Mehta, Hardeep S.; Peden, Charles H. F.

    2015-11-24

    A continuous-flow (CF) magic angle sample spinning (CF-MAS) NMR rotor and probe are described for investigating reaction dynamics, stable intermediates/transition states, and mechanisms of catalytic reactions in situ. The rotor includes a sample chamber of a flow-through design with a large sample volume that delivers a flow of reactants through a catalyst bed contained within the sample cell allowing in-situ investigations of reactants and products. Flow through the sample chamber improves diffusion of reactants and products through the catalyst. The large volume of the sample chamber enhances sensitivity permitting in situ .sup.13C CF-MAS studies at natural abundance.

  1. Nuclear magnetic resonance studies of quadrupolar nuclei and dipolar field effects

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Urban, Jeffry Todd

    Experimental and theoretical research conducted in two areas in the field of nuclear magnetic resonance (NMR) spectroscopy is presented: (1) studies of the coherent quantum-mechanical control of the angular momentum dynamics of quadrupolar (spin I > 1/2) nuclei and its application to the determination of molecular structure; and (2) applications of the long-range nuclear dipolar field to novel NMR detection methodologies.The dissertation is organized into six chapters. The first two chapters and associated appendices are intended to be pedagogical and include an introduction to the quantum mechanical theory of pulsed NMR spectroscopy and the time dependent theory of quantum mechanics.more » The third chapter describes investigations of the solid-state multiple-quantum magic angle spinning (MQMAS) NMR experiment applied to I = 5/2 quadrupolar nuclei. This work reports the use of rotary resonance-matched radiofrequency irradiation for sensitivity enhancement of the I = 5/2 MQMAS experiment. These experiments exhibited certain selective line narrowing effects which were investigated theoretically.The fourth chapter extends the discussion of multiple quantum spectroscopy of quadrupolar nuclei to a mostly theoretical study of the feasibility of enhancing the resolution of nitrogen-14 NMR of large biomolecules in solution via double-quantum spectroscopy. The fifth chapter continues to extend the principles of multiple quantum NMR spectroscopy of quadrupolar nuclei to make analogies between experiments in NMR/nuclear quadrupolar resonance (NQR) and experiments in atomic/molecular optics (AMO). These analogies are made through the Hamiltonian and density operator formalism of angular momentum dynamics in the presence of electric and magnetic fields.The sixth chapter investigates the use of the macroscopic nuclear dipolar field to encode the NMR spectrum of an analyte nucleus indirectly in the magnetization of a sensor nucleus. This technique could potentially serve as an encoding module for the recently developed NMR remote detection experiment. The feasibility of using hyperpolarized xenon-129 gas as a sensor is discussed. This work also reports the use of an optical atomic magnetometer to detect the nuclear magnetization of Xe-129 gas, which has potential applicability as a detection module for NMR remote detection experiments.« less

  2. High power coaxial ubitron

    NASA Astrophysics Data System (ADS)

    Balkcum, Adam J.

    In the ubitron, also known as the free electron laser, high power coherent radiation is generated from the interaction of an undulating electron beam with an electromagnetic signal and a static periodic magnetic wiggler field. These devices have experimentally produced high power spanning the microwave to x-ray regimes. Potential applications range from microwave radar to the study of solid state material properties. In this dissertation, the efficient production of high power microwaves (HPM) is investigated for a ubitron employing a coaxial circuit and wiggler. Designs for the particular applications of an advanced high gradient linear accelerator driver and a directed energy source are presented. The coaxial ubitron is inherently suited for the production of HPM. It utilizes an annular electron beam to drive the low loss, RF breakdown resistant TE01 mode of a large coaxial circuit. The device's large cross-sectional area greatly reduces RF wall heat loading and the current density loading at the cathode required to produce the moderate energy (500 keV) but high current (1-10 kA) annular electron beam. Focusing and wiggling of the beam is achieved using coaxial annular periodic permanent magnet (PPM) stacks without a solenoidal guide magnetic field. This wiggler configuration is compact, efficient and can propagate the multi-kiloampere electron beams required for many HPM applications. The coaxial PPM ubitron in a traveling wave amplifier, cavity oscillator and klystron configuration is investigated using linear theory and simulation codes. A condition for the dc electron beam stability in the coaxial wiggler is derived and verified using the 2-1/2 dimensional particle-in-cell code, MAGIC. New linear theories for the cavity start-oscillation current and gain in a klystron are derived. A self-consistent nonlinear theory for the ubitron-TWT and a new nonlinear theory for the ubitron oscillator are presented. These form the basis for simulation codes which, along with MAGIC, are used to design a representative 200 MW, 40% efficient, X-band amplifier for linear accelerators and a 1 GW, 21% efficient, S-band oscillator for directed energy. The technique of axial mode profiling in the ubitron cavity oscillator is also proposed and shown to increase the simulated interaction efficiency to 46%. These devices are realizable and their experimental implementation, including electron beam formation and spurious mode suppression techniques, is discussed.

  3. Size effects on the structural, electronic, and optical properties of (5,0) finite-length carbon nanotube: An ab-initio electronic structure study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tarighi Ahmadpour, Mahdi; Rostamnejadi, Ali; Hashemifar, S. Javad

    2016-07-07

    We use density functional computations to study the zero temperature structural, electronic, magnetic, and optical properties of (5,0) finite carbon nanotubes (FCNT), with length in the range of 4–44 Å. It is found that the structural and electronic properties of (5,0) FCNTs, in the ground state, converge at a length of about 30 Å, while the excited state properties exhibit long-range edge effects. We discuss that curvature effects enhance energy gap of FCNTs, in contrast to the known trend in the periodic limit. It is seen that compensation of curvature effects in two special small sizes may give rise to spontaneous magnetization.more » The obtained cohesive energies provide some insights into the effects of environment on the growth of FCNTs. The second-order difference of the total energies reveals an important magic size of about 15 Å. The optical and dynamical magnetic responses of the FCNTs to polarized electromagnetic pulses are studied by time dependent density functional theory. The results show that the static and dynamic magnetic properties mainly come from the edge carbon atoms. The optical absorption properties are described in terms of local field effects and characterized by Casida linear response method.« less

  4. Structural Biology of Supramolecular Assemblies by Magic Angle Spinning NMR Spectroscopy

    PubMed Central

    Quinn, Caitlin M.; Polenova, Tatyana

    2017-01-01

    In recent years, exciting developments in instrument technology and experimental methodology have advanced the field of magic angle spinning (MAS) NMR to new heights. Contemporary MAS NMR yields atomic-level insights into structure and dynamics of an astounding range of biological systems, many of which cannot be studied by other methods. With the advent of fast magic angle spinning, proton detection, and novel pulse sequences, large supramolecular assemblies, such as cytoskeletal proteins and intact viruses, are now accessible for detailed analysis. In this review, we will discuss the current MAS NMR methodologies that enable characterization of complex biomolecular systems and will present examples of applications to several classes of assemblies comprising bacterial and mammalian cytoskeleton as well as HIV-1 and bacteriophage viruses. The body of work reviewed herein is representative of the recent advancements in the field, with respect to the complexity of the systems studied, the quality of the data, and the significance to the biology. PMID:28093096

  5. Irrigation, fertilization and initial substrate quality effects on decomposing Loblolly pine litter chemistry

    Treesearch

    Felipe G. Sanchez

    2004-01-01

    Changes in carbon chemistry (i.e., carbon compound classes such as aromatics, phenolics, etc.) of loblolly pine (Pinus taeda L.) litter were examined during three years of decomposition under factorial combinations of irrigation and fertilization treatments. Cross polarization magic angle spinning 13C nuclear magnetic resonance...

  6. In Search of the Ultimate Building Blocks

    NASA Astrophysics Data System (ADS)

    't Hooft, Gerard

    1996-12-01

    An apology; 1. The beginning of the journey to the small: cutting paper; 2. To molecules and atoms; 3. The magic mystery of the quanta; 4. Dazzling velocities; 5. The elementary particle zoo before 1970; 6. Life and death; 7. The crazy kaons; 8. The invisible quarks; 9. Fields or bootstraps?; 10. The Yang-Mills bonanza; 11. Superconducting empty space: the Higgs-Kibble machine; 12. Models; 13. Colouring in the strong forces; 14. The magnetic monopole; 15. Gypsy; 16. The brilliance of the standard model; 17. Anomalies; 18. Deceptive perfection; 19. Weighing neutrinos; 20. The great desert; 21. Technicolor; 22. Grand unification; 23. Supergravity; 24. Eleven dimensional space-time; 25. Attaching the super string; 26. Into the black hole; 27. Theories that do not yet exist … ; 28. Dominance of the rule of the smallest.

  7. Overhauser effects in non-conducting solids at 1.2 K

    NASA Astrophysics Data System (ADS)

    Ji, X.; Can, T. V.; Mentink-Vigier, F.; Bornet, A.; Milani, J.; Vuichoud, B.; Caporini, M. A.; Griffin, R. G.; Jannin, S.; Goldman, M.; Bodenhausen, G.

    2018-01-01

    Recently, it was observed that protons in non-conducting solids doped with 1,3-bisdiphenylene-2-phenylallyl (BDPA) or its sulfonated derivative (SA-BDPA) can be polarized through Overhauser effects via resonant microwave irradiation. These effects were present under magic angle spinning conditions in magnetic fields between 5 and 18.8 T and at temperatures near 100 K. This communication reports similar effects in static samples at 6.7 T and, more importantly, at temperatures as low as 1.2 K, in a different dynamic regime than in the previous study. Our results provide new information towards understanding the mechanism of the Overhauser effect in non-conducting solids. We discuss possible origins of the fluctuations that can give rise to an Overhauser effect at such low temperatures.

  8. Organic acid modeling and model validation: Workshop summary. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sullivan, T.J.; Eilers, J.M.

    1992-08-14

    A workshop was held in Corvallis, Oregon on April 9--10, 1992 at the offices of E&S Environmental Chemistry, Inc. The purpose of this workshop was to initiate research efforts on the entitled ``Incorporation of an organic acid representation into MAGIC (Model of Acidification of Groundwater in Catchments) and testing of the revised model using Independent data sources.`` The workshop was attended by a team of internationally-recognized experts in the fields of surface water acid-bass chemistry, organic acids, and watershed modeling. The rationale for the proposed research is based on the recent comparison between MAGIC model hindcasts and paleolimnological inferences ofmore » historical acidification for a set of 33 statistically-selected Adirondack lakes. Agreement between diatom-inferred and MAGIC-hindcast lakewater chemistry in the earlier research had been less than satisfactory. Based on preliminary analyses, it was concluded that incorporation of a reasonable organic acid representation into the version of MAGIC used for hindcasting was the logical next step toward improving model agreement.« less

  9. Organic acid modeling and model validation: Workshop summary

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sullivan, T.J.; Eilers, J.M.

    1992-08-14

    A workshop was held in Corvallis, Oregon on April 9--10, 1992 at the offices of E S Environmental Chemistry, Inc. The purpose of this workshop was to initiate research efforts on the entitled Incorporation of an organic acid representation into MAGIC (Model of Acidification of Groundwater in Catchments) and testing of the revised model using Independent data sources.'' The workshop was attended by a team of internationally-recognized experts in the fields of surface water acid-bass chemistry, organic acids, and watershed modeling. The rationale for the proposed research is based on the recent comparison between MAGIC model hindcasts and paleolimnological inferencesmore » of historical acidification for a set of 33 statistically-selected Adirondack lakes. Agreement between diatom-inferred and MAGIC-hindcast lakewater chemistry in the earlier research had been less than satisfactory. Based on preliminary analyses, it was concluded that incorporation of a reasonable organic acid representation into the version of MAGIC used for hindcasting was the logical next step toward improving model agreement.« less

  10. A Study of Multi-Λ Hypernuclei Within Spherical Relativistic Mean-Field Approach

    NASA Astrophysics Data System (ADS)

    Rather, Asloob A.; Ikram, M.; Usmani, A. A.; Kumar, B.; Patra, S. K.

    2017-12-01

    This research article is a follow up of an earlier work by M. Ikram et al., reported in Int. J. Mod. Phys. E 25, 1650103 (2016) where we searched for Λ magic numbers in experimentally confirmed doubly magic nucleonic cores in light to heavy mass region (i.e., 16 O-208 P b) by injecting Λ's into them. In the present manuscript, working within the state of the art relativistic mean field theory with the inclusion of Λ N and ΛΛ interaction in addition to nucleon-meson NL 3∗ effective force, we extend the search of lambda magic numbers in multi- Λ hypernuclei using the predicted doubly magic nucleonic cores 292120, 304120, 360132, 370132, 336138, 396138 of the elusive superheavy mass regime. In analogy to well established signatures of magicity in conventional nuclear theory, the prediction of hypernuclear magicities is made on the basis of one-, two- Λ separation energy ( S Λ, S 2Λ) and two lambda shell gaps ( δ 2Λ) in multi- Λ hypernuclei. The calculations suggest that the Λ numbers 92, 106, 126, 138, 184, 198, 240, and 258 might be the Λ shell closures after introducing the Λ's in the elusive superheavy nucleonic cores. The appearance of new lambda shell closures apart from the nucleonic ones predicted by various relativistic and non-relativistic theoretical investigations can be attributed to the relatively weak strength of the spin-orbit coupling in hypernuclei compared to normal nuclei. Further, the predictions made in multi- Λ hypernuclei under study resembles closely the magic numbers in conventional nuclear theory suggested by various relativistic and non-relativistic theoretical models. Moreover, in support of the Λ shell closure, the investigation of Λ pairing energy and effective Λ pairing gap has been made. We noticed a very close agreement of the predicted Λ shell closures with the survey made on the pretext of S Λ, S 2Λ, and δ 2Λ except for the appearance of magic numbers corresponding to Λ = 156 which manifest in Λ effective pairing gap and pairing energy. Also, the lambda single-particle spectrum is analyzed to mark the energy shell gap for further strengthening the predictions made on the basis of separation energies and shell gaps. Lambda and nucleon spin-orbit interactions are analyzed to confirm the reduction in magnitude of Λ spin-orbit interaction compared to the nucleonic case, however the interaction profile is similar in both the cases. Lambda and nucleon density distributions have been investigated to reveal the impurity effect of Λ hyperons which make the depression of central density of the core of superheavy doubly magic nuclei. Lambda skin structure is also seen.

  11. Low-dimensional quantum magnetism in Cu (NCS) 2: A molecular framework material

    NASA Astrophysics Data System (ADS)

    Cliffe, Matthew J.; Lee, Jeongjae; Paddison, Joseph A. M.; Schott, Sam; Mukherjee, Paromita; Gaultois, Michael W.; Manuel, Pascal; Sirringhaus, Henning; Dutton, Siân E.; Grey, Clare P.

    2018-04-01

    Low-dimensional magnetic materials with spin-1/2 moments can host a range of exotic magnetic phenomena due to the intrinsic importance of quantum fluctuations to their behavior. Here, we report the structure, magnetic structure, and magnetic properties of copper ii thiocyanate, Cu(NCS ) 2, a one-dimensional coordination polymer which displays low-dimensional quantum magnetism. Magnetic susceptibility, electron paramagnetic resonance spectroscopy, 13C magic-angle spinning nuclear magnetic resonance spectroscopy, and density functional theory investigations indicate that Cu(NCS ) 2 behaves as a two-dimensional array of weakly coupled antiferromagnetic spin chains [J2=133 (1 ) K , α =J1/J2=0.08 ] . Powder neutron-diffraction measurements confirm that Cu(NCS ) 2 orders as a commensurate antiferromagnet below TN=12 K , with a strongly reduced ordered moment (0.3 μB ) due to quantum fluctuations.

  12. Parsivel Disdrometer Support for MAGIC Field Campaign Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kollias, Pavlos; Bartholomew, Mary Jane

    2016-06-01

    In the Marine ARM GPCI Investigation of Clouds (MAGIC) field campaign, the U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility’s second Mobile Facility (AMF2) was deployed on the Horizon Lines cargo ship Spirit traversing a route between Los Angeles, California and Honolulu, Hawaii for one full year. The transect for this deployment was chosen specifically because it crosses the stratocumulus-to-cumulus transition of the North-East Pacific, a region of great climatic interest and a close approximation to the transect used for several focused model intercomparison efforts. The cloud type and cover along this transect vary from lowmore » marine stratocumulus with high areal coverage near the California coast to isolated shallow cumulus with much lower areal coverage in the trade wind regime near Hawaii. The low marine stratocumulus decks, with their high albedo, exert a major influence on the shortwave radiation budget in the ocean environment, and thus provide an extremely important forcing of Earth’s climate. The trade cumulus clouds play a large role in the global surface evaporation and also in Earth’s albedo. One of the important science drivers of the MAGIC campaign was to measure the properties of clouds and precipitation, specifically cloud type, fractional coverage, base height, physical thickness, liquid water path (LWP), optical depth, and drizzle and precipitation frequency, amount, and extent. Retrievals of cloud and precipitation properties during the MAGIC campaign relied critically on the calibration of the AMF2 radar systems. For MAGIC this included the KAZR and M-WACR, both fixed zenith-pointing systems, and the 1290 MHz beam steerable wind profiler.« less

  13. Floquet-Magnus expansion for general N-coupled spins systems in magic-angle spinning nuclear magnetic resonance spectra

    NASA Astrophysics Data System (ADS)

    Mananga, Eugene Stephane; Charpentier, Thibault

    2015-04-01

    In this paper we present a theoretical perturbative approach for describing the NMR spectrum of strongly dipolar-coupled spin systems under fast magic-angle spinning. Our treatment is based on two approaches: the Floquet approach and the Floquet-Magnus expansion. The Floquet approach is well known in the NMR community as a perturbative approach to get analytical approximations. Numerical procedures are based on step-by-step numerical integration of the corresponding differential equations. The Floquet-Magnus expansion is a perturbative approach of the Floquet theory. Furthermore, we address the " γ -encoding" effect using the Floquet-Magnus expansion approach. We show that the average over " γ " angle can be performed for any Hamiltonian with γ symmetry.

  14. Multi-wavelength study of flaring activity in BL Lac object S5 0716+714 during the 2015 outburst

    DOE PAGES

    Chandra, Sunil; Zhang, Haocheng; Kushwaha, Pankaj; ...

    2015-08-17

    We present a detailed investigation of the flaring activity observed from a BL Lac object, S5 0716+714 , during its brightest ever optical state in the second half of 2015 January. Observed almost simultaneously in the optical, X-rays, and γ-rays, a significant change in the degree of optical polarization (PD) and a swing in the position angle (PA) of polarization were recorded. A TeV (VHE) detection was also reported by the MAGIC consortium during this flaring episode. Two prominent sub-flares, peaking about five days apart, were seen in almost all of the energy bands. The multi-wavelength light curves, spectral energymore » distribution, and polarization are modeled using the time-dependent code developed by Zhang et al. This model assumes a straight jet threaded by large-scale helical magnetic fields taking into account the light travel time effects, incorporating synchrotron flux and polarization in 3D geometry. Furthermore, the rapid variation in PD and rotation in PA are most likely due to reconnections happening in the emission region in the jet, as suggested by the change in the ratio of toroidal to poloidal components of the magnetic field during the quiescent and flaring states.« less

  15. Multi-wavelength study of flaring activity in BL Lac object S5 0716+714 during the 2015 outburst

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chandra, Sunil; Zhang, Haocheng; Kushwaha, Pankaj

    We present a detailed investigation of the flaring activity observed from a BL Lac object, S5 0716+714 , during its brightest ever optical state in the second half of 2015 January. Observed almost simultaneously in the optical, X-rays, and γ-rays, a significant change in the degree of optical polarization (PD) and a swing in the position angle (PA) of polarization were recorded. A TeV (VHE) detection was also reported by the MAGIC consortium during this flaring episode. Two prominent sub-flares, peaking about five days apart, were seen in almost all of the energy bands. The multi-wavelength light curves, spectral energymore » distribution, and polarization are modeled using the time-dependent code developed by Zhang et al. This model assumes a straight jet threaded by large-scale helical magnetic fields taking into account the light travel time effects, incorporating synchrotron flux and polarization in 3D geometry. Furthermore, the rapid variation in PD and rotation in PA are most likely due to reconnections happening in the emission region in the jet, as suggested by the change in the ratio of toroidal to poloidal components of the magnetic field during the quiescent and flaring states.« less

  16. MULTI-WAVELENGTH STUDY OF FLARING ACTIVITY IN BL Lac OBJECT S5 0716+714 DURING THE 2015 OUTBURST

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chandra, Sunil; Kushwaha, Pankaj; Singh, K. P.

    We present a detailed investigation of the flaring activity observed from a BL Lac object, S5 0716+714 , during its brightest ever optical state in the second half of 2015 January. Observed almost simultaneously in the optical, X-rays, and γ-rays, a significant change in the degree of optical polarization (PD) and a swing in the position angle (PA) of polarization were recorded. A TeV (VHE) detection was also reported by the MAGIC consortium during this flaring episode. Two prominent sub-flares, peaking about five days apart, were seen in almost all of the energy bands. The multi-wavelength light curves, spectral energymore » distribution, and polarization are modeled using the time-dependent code developed by Zhang et al. This model assumes a straight jet threaded by large-scale helical magnetic fields taking into account the light travel time effects, incorporating synchrotron flux and polarization in 3D geometry. The rapid variation in PD and rotation in PA are most likely due to reconnections happening in the emission region in the jet, as suggested by the change in the ratio of toroidal to poloidal components of the magnetic field during the quiescent and flaring states.« less

  17. MAGIC polymer gel for dosimetric verification in boron neutron capture therapy

    PubMed Central

    Heikkinen, Sami; Kotiluoto, Petri; Serén, Tom; Seppälä, Tiina; Auterinen, Iiro; Savolainen, Sauli

    2007-01-01

    Radiation‐sensitive polymer gels are among the most promising three‐dimensional dose verification tools developed to date. We tested the normoxic polymer gel dosimeter known by the acronym MAGIC (methacrylic and ascorbic acid in gelatin initiated by copper) to evaluate its use in boron neutron capture therapy (BNCT) dosimetry. We irradiated a large cylindrical gel phantom (diameter: 10 cm; length: 20 cm) in the epithermal neutron beam of the Finnish BNCT facility at the FiR 1 nuclear reactor. Neutron irradiation was simulated with a Monte Carlo radiation transport code MCNP. To compare dose–response, gel samples from the same production batch were also irradiated with 6 MV photons from a medical linear accelerator. Irradiated gel phantoms then underwent magnetic resonance imaging to determine their R2 relaxation rate maps. The measured and normalized dose distribution in the epithermal neutron beam was compared with the dose distribution calculated by computer simulation. The results support the feasibility of using MAGIC gel in BNCT dosimetry. PACS numbers: 87.53.Qc, 87.53.Wz, 87.66.Ff PMID:17592463

  18. Magic angle for barrier-controlled double quantum dots

    NASA Astrophysics Data System (ADS)

    Yang, Xu-Chen; Wang, Xin

    2018-01-01

    We show that the exchange interaction of a singlet-triplet spin qubit confined in double quantum dots, when being controlled by the barrier method, is insensitive to a charged impurity lying along certain directions away from the center of the double-dot system. These directions differ from the polar axis of the double dots by the magic angle, equaling arccos(1 /√{3 })≈54 .7∘ , a value previously found in atomic physics and nuclear magnetic resonance. This phenomenon can be understood from an expansion of the additional Coulomb interaction created by the impurity, but also relies on the fact that the exchange interaction solely depends on the tunnel coupling in the barrier-control scheme. Our results suggest that for a scaled-up qubit array, when all pairs of double dots rotate their respective polar axes from the same reference line by the magic angle, crosstalk between qubits can be eliminated, allowing clean single-qubit operations. While our model is a rather simplified version of actual experiments, our results suggest that it is possible to minimize unwanted couplings by judiciously designing the layout of the qubits.

  19. Biopolymer nanocomposite films reinforced with nanocellulose whiskers

    Treesearch

    Amit Saxena; Marcus Foston; Mohamad Kassaee; Thomas J. Elder; Arthur J. Ragauskas

    2011-01-01

    A xylan nanocomposite film with improved strength and barrier properties was prepared by a solution casting using nanocellulose whiskers as a reinforcing agent. The 13C cross-polarization magic angle spinning (CP/MAS) nuclear magnetic resonance (NMR) analysis of the spectral data obtained for the NCW/xylan nanocomposite films indicated the signal intensity originating...

  20. Evaluation of Cancer Metabolomics Using ex vivo High Resolution Magic Angle Spinning (HRMAS) Magnetic Resonance Spectroscopy (MRS)

    PubMed Central

    Fuss, Taylor L.; Cheng, Leo L.

    2016-01-01

    According to World Health Organization (WHO) estimates, cancer is responsible for more deaths than all coronary heart disease or stroke worldwide, serving as a major public health threat around the world. High resolution magic angle spinning (HRMAS) magnetic resonance spectroscopy (MRS) has demonstrated its usefulness in the identification of cancer metabolic markers with the potential to improve diagnosis and prognosis for the oncology clinic, due partially to its ability to preserve tissue architecture for subsequent histological and molecular pathology analysis. Capable of the quantification of individual metabolites, ratios of metabolites, and entire metabolomic profiles, HRMAS MRS is one of the major techniques now used in cancer metabolomic research. This article reviews and discusses literature reports of HRMAS MRS studies of cancer metabolomics published between 2010 and 2015 according to anatomical origins, including brain, breast, prostate, lung, gastrointestinal, and neuroendocrine cancers. These studies focused on improving diagnosis and understanding patient prognostication, monitoring treatment effects, as well as correlating with the use of in vivo MRS in cancer clinics. PMID:27011205

  1. Metabolomics by Proton High-Resolution Magic-Angle-Spinning Nuclear Magnetic Resonance of Tomato Plants Treated with Two Secondary Metabolites Isolated from Trichoderma.

    PubMed

    Mazzei, Pierluigi; Vinale, Francesco; Woo, Sheridan Lois; Pascale, Alberto; Lorito, Matteo; Piccolo, Alessandro

    2016-05-11

    Trichoderma fungi release 6-pentyl-2H-pyran-2-one (1) and harzianic acid (2) secondary metabolites to improve plant growth and health protection. We isolated metabolites 1 and 2 from Trichoderma strains, whose different concentrations were used to treat seeds of Solanum lycopersicum. The metabolic profile in the resulting 15 day old tomato leaves was studied by high-resolution magic-angle-spinning nuclear magnetic resonance (HRMAS NMR) spectroscopy directly on the whole samples without any preliminary extraction. Principal component analysis (PCA) of HRMAS NMR showed significantly enhanced acetylcholine and γ-aminobutyric acid (GABA) content accompanied by variable amount of amino acids in samples treated with both Trichoderma secondary metabolites. Seed germination rates, seedling fresh weight, and the metabolome of tomato leaves were also dependent upon doses of metabolites 1 and 2 treatments. HRMAS NMR spectroscopy was proven to represent a rapid and reliable technique for evaluating specific changes in the metabolome of plant leaves and calibrating the best concentration of bioactive compounds required to stimulate plant growth.

  2. Solid state nuclear magnetic resonance with magic-angle spinning and dynamic nuclear polarization below 25 K

    PubMed Central

    Thurber, Kent R.; Potapov, Alexey; Yau, Wai-Ming; Tycko, Robert

    2012-01-01

    We describe an apparatus for solid state nuclear magnetic resonance (NMR) with dynamic nuclear polarization (DNP) and magic-angle spinning (MAS) at 20–25 K and 9.4 Tesla. The MAS NMR probe uses helium to cool the sample space and nitrogen gas for MAS drive and bearings, as described earlier (Thurber et al., J. Magn. Reson. 2008) [1], but also includes a corrugated waveguide for transmission of microwaves from below the probe to the sample. With a 30 mW circularly polarized microwave source at 264 GHz, MAS at 6.8 kHz, and 21 K sample temperature, greater than 25-fold enhancements of cross-polarized 13C NMR signals are observed in spectra of frozen glycerol/water solutions containing the triradical dopant DOTOPA-TEMPO when microwaves are applied. As demonstrations, we present DNP-enhanced one-dimensional and two-dimensional 13C MAS NMR spectra of frozen solutions of uniformly 13C-labeled L-alanine and melittin, a 26-residue helical peptide that we have synthesized with four uniformly 13C-labeled amino acids. PMID:23238592

  3. Solid state nuclear magnetic resonance with magic-angle spinning and dynamic nuclear polarization below 25 K.

    PubMed

    Thurber, Kent R; Potapov, Alexey; Yau, Wai-Ming; Tycko, Robert

    2013-01-01

    We describe an apparatus for solid state nuclear magnetic resonance (NMR) with dynamic nuclear polarization (DNP) and magic-angle spinning (MAS) at 20-25 K and 9.4 Tesla. The MAS NMR probe uses helium to cool the sample space and nitrogen gas for MAS drive and bearings, as described earlier, but also includes a corrugated waveguide for transmission of microwaves from below the probe to the sample. With a 30 mW circularly polarized microwave source at 264 GHz, MAS at 6.8 kHz, and 21 K sample temperature, greater than 25-fold enhancements of cross-polarized (13)C NMR signals are observed in spectra of frozen glycerol/water solutions containing the triradical dopant DOTOPA-TEMPO when microwaves are applied. As demonstrations, we present DNP-enhanced one-dimensional and two-dimensional (13)C MAS NMR spectra of frozen solutions of uniformly (13)C-labeled l-alanine and melittin, a 26-residue helical peptide that we have synthesized with four uniformly (13)C-labeled amino acids. Published by Elsevier Inc.

  4. Application of High-Resolution Magic-Angle Spinning NMR Spectroscopy to Define the Cell Uptake of MRI Contrast Agents

    NASA Astrophysics Data System (ADS)

    Calabi, Luisella; Alfieri, Goffredo; Biondi, Luca; De Miranda, Mario; Paleari, Lino; Ghelli, Stefano

    2002-06-01

    A new method, based on proton high-resolution magic-angle spinning ( 1H HR-MAS) NMR spectroscopy, has been employed to study the cell uptake of magnetic resonance imaging contrast agents (MRI-CAs). The method was tested on human red blood cells (HRBC) and white blood cells (HWBC) by using three gadolinium complexes, widely used in diagnostics, Gd-BOPTA, Gd-DTPA, and Gd-DOTA, and the analogous complexes obtained by replacing Gd(III) with Dy(III), Nd(III), and Tb(III) (i.e., complexes isostructural to the ones of gadolinium but acting as shift agents). The method is based on the evaluation of the magnetic effects, line broadening, or induced lanthanide shift (LIS) caused by these complexes on NMR signals of intra- and extracellular water. Since magnetic effects are directly linked to permeability, this method is direct. In all the tests, these magnetic effects were detected for the extracellular water signal only, providing a direct proof that these complexes are not able to cross the cell membrane. Line broadening effects (i.e., the use of gadolinium complexes) only allow qualitative evaluations. On the contrary, LIS effects can be measured with high precision and they can be related to the concentration of the paramagnetic species in the cellular compartments. This is possible because the HR-MAS technique provides the complete elimination of bulk magnetic susceptibility (BMS) shift and the differentiation of extra- and intracellular water signals. Thus with this method, the rapid quantification of the MRI-CA amount inside and outside the cells is actually feasible.

  5. Development of a composite large-size SiPM (assembled matrix) based modular detector cluster for MAGIC

    NASA Astrophysics Data System (ADS)

    Hahn, A.; Mazin, D.; Bangale, P.; Dettlaff, A.; Fink, D.; Grundner, F.; Haberer, W.; Maier, R.; Mirzoyan, R.; Podkladkin, S.; Teshima, M.; Wetteskind, H.

    2017-02-01

    The MAGIC collaboration operates two 17 m diameter Imaging Atmospheric Cherenkov Telescopes (IACTs) on the Canary Island of La Palma. Each of the two telescopes is currently equipped with a photomultiplier tube (PMT) based imaging camera. Due to the advances in the development of Silicon Photomultipliers (SiPMs), they are becoming a widely used alternative to PMTs in many research fields including gamma-ray astronomy. Within the Otto-Hahn group at the Max Planck Institute for Physics, Munich, we are developing a SiPM based detector module for a possible upgrade of the MAGIC cameras and also for future experiments as, e.g., the Large Size Telescopes (LST) of the Cherenkov Telescope Array (CTA). Because of the small size of individual SiPM sensors (6 mm×6 mm) with respect to the 1-inch diameter PMTs currently used in MAGIC, we use a custom-made matrix of SiPMs to cover the same detection area. We developed an electronic circuit to actively sum up and amplify the SiPM signals. Existing non-imaging hexagonal light concentrators (Winston cones) used in MAGIC have been modified for the angular acceptance of the SiPMs by using C++ based ray tracing simulations. The first prototype based detector module includes seven channels and was installed into the MAGIC camera in May 2015. We present the results of the first prototype and its performance as well as the status of the project and discuss its challenges.

  6. Advances/applications of MAGIC and SOS

    NASA Astrophysics Data System (ADS)

    Warren, Gary; Ludeking, Larry; Nguyen, Khanh; Smithe, David; Goplen, Bruce

    1993-12-01

    MAGIC and SOS have been applied to investigate a variety of accelerator-related devices. Examples include high brightness electron guns, beam-RF interactions in klystrons, cold-test modes in an RFQ and in RF sources, and a high-quality, flexible, electron gun with operating modes appropriate for gyrotrons, peniotrons, and other RF sources. Algorithmic improvements for PIC have been developed and added to MAGIC and SOS to facilitate these modeling efforts. Two new field algorithms allow improved control of computational numerical noise and selective control of harmonic modes in RF cavities. An axial filter in SOS accelerates simulations in cylindrical coordinates. The recent addition of an export/import feature now allows long devices to be modeled in sections. Interfaces have been added to receive electromagnetic field information from the Poisson group of codes and from EGUN and to send beam information to PARMELA for subsequent tracing of bunches through beam optics. Post-processors compute and display beam properties including geometric, normalized, and slice emittances, and phase-space parameters, and video. VMS, UNIX, and DOS versions are supported, with migration underway toward windows environments.

  7. Oligo-branched peptides for tumor targeting: from magic bullets to magic forks.

    PubMed

    Falciani, Chiara; Pini, Alessandro; Bracci, Luisa

    2009-02-01

    Selective targeting of tumor cells is the final goal of research and drug discovery for cancer diagnosis, imaging and therapy. After the invention of hybridoma technology, the concept of magic bullet was introduced into the field of oncology, referring to selective killing of tumor cells, by specific antibodies. More recently, small molecules and peptides have also been proposed as selective targeting agents. We analyze the state of the art of tumor-selective agents that are presently available and tested in clinical settings. A novel approach based on 'armed' oligo-branched peptides as tumor targeting agents, is discussed and compared with existing tumor-selective therapies mediated by antibodies, small molecules or monomeric peptides. Oligo-branched peptides could be novel drugs that combine the advantages of antibodies and small molecules.

  8. Binding Energy of 79Cu: Probing the Structure of the Doubly Magic 78Ni from Only One Proton Away

    NASA Astrophysics Data System (ADS)

    Welker, A.; Althubiti, N. A. S.; Atanasov, D.; Blaum, K.; Cocolios, T. E.; Herfurth, F.; Kreim, S.; Lunney, D.; Manea, V.; Mougeot, M.; Neidherr, D.; Nowacki, F.; Poves, A.; Rosenbusch, M.; Schweikhard, L.; Wienholtz, F.; Wolf, R. N.; Zuber, K.

    2017-11-01

    The masses of the neutron-rich copper isotopes 75-79Cu are determined using the precision mass spectrometer ISOLTRAP at the CERN-ISOLDE facility. The trend from the new data differs significantly from that of previous results, offering a first accurate view of the mass surface adjacent to the Z =28 , N =50 nuclide 78Ni and supporting a doubly magic character. The new masses compare very well with large-scale shell-model calculations that predict shape coexistence in a doubly magic 78Ni and a new island of inversion for Z <28 . A coherent picture of this important exotic region begins to emerge where excitations across Z =28 and N =50 form a delicate equilibrium with a spherical mean field.

  9. Modeling magnetic field and TEC signatures of large-amplitude acoustic and gravity waves generated by natural hazard events

    NASA Astrophysics Data System (ADS)

    Zettergren, M. D.; Snively, J. B.; Inchin, P.; Komjathy, A.; Verkhoglyadova, O. P.

    2017-12-01

    Ocean and solid earth responses during earthquakes are a significant source of large amplitude acoustic and gravity waves (AGWs) that perturb the overlying ionosphere-thermosphere (IT) system. IT disturbances are routinely detected following large earthquakes (M > 7.0) via GPS total electron content (TEC) observations, which often show acoustic wave ( 3-4 min periods) and gravity wave ( 10-15 min) signatures with amplitudes of 0.05-2 TECU. In cases of very large earthquakes (M > 8.0) the persisting acoustic waves are estimated to have 100-200 m/s compressional velocities in the conducting ionospheric E and F-regions and should generate significant dynamo currents and magnetic field signatures. Indeed, some recent reports (e.g. Hao et al, 2013, JGR, 118, 6) show evidence for magnetic fluctuations, which appear to be related to AGWs, following recent large earthquakes. However, very little quantitative information is available on: (1) the detailed spatial and temporal dependence of these magnetic fluctuations, which are usually observed at a small number of irregularly arranged stations, and (2) the relation of these signatures to TEC perturbations in terms of relative amplitudes, frequency, and timing for different events. This work investigates space- and time-dependent behavior of both TEC and magnetic fluctuations following recent large earthquakes, with the aim to improve physical understanding of these perturbations via detailed, high-resolution, two- and three-dimensional modeling case studies with a coupled neutral atmospheric and ionospheric model, MAGIC-GEMINI (Zettergren and Snively, 2015, JGR, 120, 9). We focus on cases inspired by the large Chilean earthquakes from the past decade (viz., the M > 8.0 earthquakes from 2010 and 2015) to constrain the sources for the model, i.e. size, frequency, amplitude, and timing, based on available information from ocean buoy and seismometer data. TEC data are used to validate source amplitudes and to constrain background ionospheric conditions. Preliminary comparisons against available magnetic field and TEC data from these events provide evidence, albeit limited and localized, that support the validity of the spatially-resolved simulation results.

  10. Entanglement of light-shift compensated atomic spin waves with telecom light.

    PubMed

    Dudin, Y O; Radnaev, A G; Zhao, R; Blumoff, J Z; Kennedy, T A B; Kuzmich, A

    2010-12-31

    Entanglement of a 795 nm light polarization qubit and an atomic Rb spin-wave qubit for a storage time of 0.1 s is observed by measuring the violation of Bell's inequality (S=2.65±0.12). Long qubit storage times are achieved by pinning the spin wave in a 1064 nm wavelength optical lattice, with a magic-valued magnetic field superposed to eliminate lattice-induced dephasing. Four-wave mixing in a cold Rb gas is employed to perform light qubit conversion between near infrared (795 nm) and telecom (1367 nm) wavelengths, and after propagation in a telecom fiber, to invert the conversion process. Observed Bell inequality violation (S=2.66±0.09), at 10 ms storage, confirms preservation of memory-light entanglement through the two stages of light qubit frequency conversion.

  11. Discovery of very high energy γ-ray emission from the blazar 1ES 0033+595 by the MAGIC telescopes

    NASA Astrophysics Data System (ADS)

    Aleksić, J.; Ansoldi, S.; Antonelli, L. A.; Antoranz, P.; Babic, A.; Bangale, P.; Barres de Almeida, U.; Barrio, J. A.; Becerra González, J.; Bednarek, W.; Berger, K.; Bernardini, E.; Biland, A.; Blanch, O.; Bonnefoy, S.; Bonnoli, G.; Borracci, F.; Bretz, T.; Carmona, E.; Carosi, A.; Carreto Fidalgo, D.; Colin, P.; Colombo, E.; Contreras, J. L.; Cortina, J.; Covino, S.; da Vela, P.; Dazzi, F.; de Angelis, A.; de Caneva, G.; de Lotto, B.; Delgado Mendez, C.; Doert, M.; Domínguez, A.; Dominis Prester, D.; Dorner, D.; Doro, M.; Einecke, S.; Eisenacher, D.; Elsaesser, D.; Farina, E.; Ferenc, D.; Fonseca, M. V.; Font, L.; Frantzen, K.; Fruck, C.; García López, R. J.; Garczarczyk, M.; Garrido Terrats, D.; Gaug, M.; Godinović, N.; González Muñoz, A.; Gozzini, S. R.; Hadasch, D.; Hayashida, M.; Herrera, J.; Herrero, A.; Hildebrand, D.; Hose, J.; Hrupec, D.; Idec, W.; Kadenius, V.; Kellermann, H.; Kodani, K.; Konno, Y.; Krause, J.; Kubo, H.; Kushida, J.; La Barbera, A.; Lelas, D.; Lewandowska, N.; Lindfors, E.; Lombardi, S.; López, M.; López-Coto, R.; López-Oramas, A.; Lorenz, E.; Lozano, I.; Makariev, M.; Mallot, K.; Maneva, G.; Mankuzhiyil, N.; Mannheim, K.; Maraschi, L.; Marcote, B.; Mariotti, M.; Martínez, M.; Mazin, D.; Menzel, U.; Meucci, M.; Miranda, J. M.; Mirzoyan, R.; Moralejo, A.; Munar-Adrover, P.; Nakajima, D.; Niedzwiecki, A.; Nilsson, K.; Nishijima, K.; Noda, K.; Nowak, N.; Orito, R.; Overkemping, A.; Paiano, S.; Palatiello, M.; Paneque, D.; Paoletti, R.; Paredes, J. M.; Paredes-Fortuny, X.; Partini, S.; Persic, M.; Prada, F.; Moroni, P. G. Prada; Prandini, E.; Preziuso, S.; Puljak, I.; Reinthal, R.; Rhode, W.; Ribó, M.; Rico, J.; Rodriguez Garcia, J.; Rügamer, S.; Saggion, A.; Saito, T.; Saito, K.; Satalecka, K.; Scalzotto, V.; Scapin, V.; Schultz, C.; Schweizer, T.; Shore, S. N.; Sillanpää, A.; Sitarek, J.; Snidaric, I.; Sobczynska, D.; Spanier, F.; Stamatescu, V.; Stamerra, A.; Steinbring, T.; Storz, J.; Sun, S.; Surić, T.; Takalo, L.; Takami, H.; Tavecchio, F.; Temnikov, P.; Terzić, T.; Tescaro, D.; Teshima, M.; Thaele, J.; Tibolla, O.; Torres, D. F.; Toyama, T.; Treves, A.; Uellenbeck, M.; Vogler, P.; Wagner, R. M.; Zandanel, F.; Zanin, R.; MAGIC Collaboration; Tronconi, V.; Buson, S.; Borghese, A.

    2015-01-01

    The number of known very high energy (VHE) blazars is ˜50, which is very small in comparison to the number of blazars detected in other frequencies. This situation is a handicap for population studies of blazars, which emit about half of their luminosity in the γ-ray domain. Moreover, VHE blazars, if distant, allow for the study of the environment that the high-energy γ-rays traverse in their path towards the Earth, like the extragalactic background light (EBL) and the intergalactic magnetic field (IGMF), and hence they have a special interest for the astrophysics community. We present the first VHE detection of 1ES 0033+595 with a statistical significance of 5.5σ. The VHE emission of this object is constant throughout the MAGIC observations (2009 August and October), and can be parametrized with a power law with an integral flux above 150 GeV of (7.1 ± 1.3) × 10-12 photons cm-2 s-1 and a photon index of (3.8 ± 0.7). We model its spectral energy distribution (SED) as the result of inverse Compton scattering of synchrotron photons. For the study of the SED, we used simultaneous optical R-band data from the KVA telescope, archival X-ray data by Swift as well as INTEGRAL, and simultaneous high-energy (HE, 300 MeV-10 GeV) γ-ray data from the Fermi Large Area Telescope (LAT) observatory. Using the empirical approach of Prandini et al. (2010) and the Fermi LAT and MAGIC spectra for this object, we estimate the redshift of this source to be 0.34 ± 0.08 ± 0.05. This is a relevant result because this source is possibly one of the 10 most distant VHE blazars known to date, and with further (simultaneous) observations could play an important role in blazar population studies, as well as future constraints on the EBL and IGMF.

  12. Understanding the Interiors of Saturn and Mercury through Magnetic Field Observation and Dynamo Modeling

    NASA Astrophysics Data System (ADS)

    Cao, Hao

    Understanding the interior structure and dynamics of a planet is a key step towards understanding the formation and evolution of a planet. In this thesis, I combine field observation and dynamo modeling to understand planetary interiors. Focus has been put on planets Saturn and Mercury. The Cassini spacecraft has been taking continuous measurements in the Saturnian system since the Saturn orbital insertion in June 2004. Since the Mercury orbital insertion in March 2011, the MESSENGER spacecraft has been examining planet Mercury. After analyzing the close-in portion of the in-situ Cassini magnetometer measurements around Saturn, I find that Saturn's magnetic field features several surprising characteristics. First, Saturn's magnetic field is extremely axisymmetric. We cannot find any consistent departure from axisymmetry, and have put an extremely tight upper bound on the dipole tilt of Saturn: the dipole tilt of Saturn has to be smaller than 0.06 degrees. Second, we find that Saturn's magnetic field is extremely stable with time. Third, we estimated the magnetic moments of Saturn up to degree 5. This is the first magnetic field model for Saturn which goes beyond degree 3. We find that not only Saturn's intrinsic magnetic field is dominated by the axial moments; among these axial moments the odd degree ones dominate. In addition, the first three odd degree axial moments all take the same sign. This sign pattern of Saturn's magnetic moments is in contrast to that of the Earth's magnetic moments which takes alternative signs for the past century. The contrast between the geometries of Saturn's magnetic field and the Earth's magnetic field lead us to propose a dynamo hypothesis which speculates that such differences are caused by structural and dynamical differences inside these two planets. Our dynamo hypothesis for Saturn has two essential ingredients. The first concerns about the existence and size of a central core inside Saturn and its influence on Saturn's dynamo action. The second concerns about the possible heterogeneous heat transfer efficiency in the outer envelope of Saturn and its influence on Saturn's dynamo action. We then carried out numerical convective dynamo simulations using the community dynamo code MagIC version 3.44 to test our dynamo hypothesis. In our numerical dynamo experiments, the central core sizes and the outer boundary heat flow heterogeneities are both varied. We find that the central core size is an important factor that can strongly influence the geometry of the dynamo generated magnetic field. Such influence is rendered through the tangent cylinder, which is an imaginary cylinder with its axis parallel to the spin axis of the planet and is tangent to the central core at the equator. We find that both the convective motion and the magnetic field generation efficiency, represented by kinetic helicity, are weaker inside the tangent cylinder than those outside the tangent cylinder. As a result, the magnetic fields inside the tangent cylinder are consistently weaker than those outside the tangent cylinder. Thus the lack of a polar field minimum region at Saturn could be indicative of the absence or a small central core inside Saturn. MESSENGER observations revealed that Mercury's magnetic field is more unusual than previously thought. In particular, Mercury's magnetic field is strongly north-south asymmetric: the magnetic field strength in the northern hemisphere is three times as strong as that in the southern hemisphere. Yet, there is no evidence for any such north-south asymmetry in the basic properties of Mercury that could possibly influence the present-day dynamo action. Here we propose a mechanism to break the equatorial symmetry of Mercury's magnetic field within the framework of convective dynamos. The essence of our mechanism is the mutual excitation of two fundamental modes of columnar convection in rapidly rotating spherical shells. Such mutual excitation results in equatorially asymmetric kinetic helicity, which then leads to equatorially asymmetric magnetic field. With numerical dynamo experiments, we find two necessary conditions to reproduce the equatorial symmetry breaking of Mercury's magnetic field with equatorially symmetric core-mantle boundary (CMB) heat flows. The first is that buoyancy sources need to be distributed within an extended volume of the outer core rather than being concentrated near the inner boundary. The second is an equatorially peaked CMB heat flow. From this study, we conclude that 1) Mercury's core dynamo is likely powered by distributed buoyancy sources and thus is different from the present-day geodynamo which is predominantly powered by bottom-up inner core growth; 2) Mercury's mantle structure and dynamics could be favoring higher heat flow from the equatorial region of Mercury's core. (Abstract shortened by UMI.)

  13. Magnetic Pair Creation Attenuation Altitude Constraints in Gamma-Ray Pulsars

    NASA Astrophysics Data System (ADS)

    Baring, Matthew; Story, Sarah

    The Fermi gamma-ray pulsar database now exceeds 150 sources and has defined an important part of Fermi's science legacy, providing rich information for the interpretation of young energetic pulsars and old millisecond pulsars. Among the well established population characteristics is the common occurrence of exponential turnovers in the 1-10 GeV range. These turnovers are too gradual to arise from magnetic pair creation in the strong magnetic fields of pulsar inner magnetospheres, so their energy can be used to provide lower bounds to the typical altitude of GeV band emission. We explore such constraints due to single-photon pair creation transparency at and below the turnover energy. Our updated computations span both domains when general relativistic influences are important and locales where flat spacetime photon propagation is modified by rotational aberration effects. The altitude bounds, typically in the range of 2-5 stellar radii, provide key information on the emission altitude in radio quiet pulsars that do not possess double-peaked pulse profiles. However, the exceptional case of the Crab pulsar provides an altitude bound of around 20% of the light cylinder radius if pair transparency persists out to 350 GeV, the maximum energy detected by MAGIC. This is an impressive new physics-based constraint on the Crab's gamma-ray emission locale.

  14. Creating Magic Squares.

    ERIC Educational Resources Information Center

    Lyon, Betty Clayton

    1990-01-01

    One method of making magic squares using a prolongated square is illustrated. Discussed are third-order magic squares, fractional magic squares, fifth-order magic squares, decimal magic squares, and even magic squares. (CW)

  15. The impact of the oxygen scavenger on the dose-rate dependence and dose sensitivity of MAGIC type polymer gels

    NASA Astrophysics Data System (ADS)

    Khan, Muzafar; Heilemann, Gerd; Kuess, Peter; Georg, Dietmar; Berg, Andreas

    2018-03-01

    Recent developments in radiation therapy aimed at more precise dose delivery along with higher dose gradients (dose painting) and more efficient dose delivery with higher dose rates e.g. flattening filter free (FFF) irradiation. Magnetic-resonance-imaging based polymer gel dosimetry offers 3D information for precise dose delivery techniques. Many of the proposed polymer gels have been reported to exhibit a dose response, measured as relaxation rate ΔR2(D), which is dose rate dependent. A lack of or a reduced dose-rate sensitivity is very important for dosimetric accuracy, especially with regard to the increasing clinical use of FFF irradiation protocols with LINACs at high dose rates. Some commonly used polymer gels are based on Methacrylic-Acid-Gel-Initiated-by-Copper (MAGIC). Here, we report on the dose sensitivity (ΔR2/ΔD) of MAGIC-type gels with different oxygen scavenger concentration for their specific dependence on the applied dose rate in order to improve the dosimetric performance, especially for high dose rates. A preclinical x-ray machine (‘Yxlon’, E  =  200 kV) was used for irradiation to cover a range of dose rates from low \\dot{D} min  =  0.6 Gy min-1 to high \\dot{D} max  =  18 Gy min-1. The dose response was evaluated using R2-imaging of the gel on a human high-field (7T) MR-scanner. The results indicate that all of the investigated dose rates had an impact on the dose response in polymer gel dosimeters, being strongest in the high dose region and less effective for low dose levels. The absolute dose rate dependence \\frac{(Δ R2/Δ D)}{Δ \\dot{D}} of the dose response in MAGIC-type gel is significantly reduced using higher concentrations of oxygen scavenger at the expense of reduced dose sensitivity. For quantitative dose evaluations the relative dose rate dependence of a polymer gel, normalized to its sensitivity is important. Based on this normalized sensitivity the dose rate sensitivity was reduced distinctly using an increased oxygen scavenger concentration with reference to standard MAGIC-type gel formulation at high dose rate levels. The proposed gel composition with high oxygen scavenger concentration exhibits a larger linear active dose response and might be used especially in FFF-radiation applications and preclinical dosimetry at high dose rates. We propose in general to use high dose rates for calibration and evaluation as the change in relative dose sensitivity is reduced at higher dose rates in all of the investigated gel types.

  16. Graph theory and the Virasoro master equation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Obers, N.A.J.

    1991-04-01

    A brief history of affine Lie algebra, the Virasoro algebra and its culmination in the Virasoro master equations is given. By studying ansaetze of the master equation, we obtain exact solutions and gain insight in the structure of large slices of affine-Virasoro space. We find an isomorphism between the constructions in the ansatz SO(n){sub diag}, which is a set of unitary, generically irrational affine-Virasoro constructions on SO(n), and the unlabelled graphs, while, conversely, a group-theoretic and conformal field-theoretic identification is obtained for every graph of graph theory. We also define a class of magic'' Lie group bases in which themore » Virasoro master equation admits a simple metric ansatz (gmetric), whose structure is visible in the high-level expansion. When a magic basis is real on compact g, the corresponding g{sub metric} is a large system of unitary, generically irrational conformal field theories. Examples in this class include the graph-theory ansatz SO(n){sub diag} in the Cartesian basis of SO(n), and the ansatz SU(n){sub metric} in the Pauli-like basis of SU(n). Finally, we define the sine-area graphs'' of SU(n), which label the conformal field theories of SU(n){sub metric}, and we note that, in similar fashion, each magic basis of g defines a generalized graph theory on g which labels the conformal field theories of g{sub metric}. 24 figs., 4 tabs.« less

  17. Studies of an Isolated 15N- 15N Spin Pair. Off-Angle Fast-Sample-Spinning NMR and Self-Consistent-Field Calculations for Diazo Systems

    NASA Astrophysics Data System (ADS)

    Challoner, Robin; Harris, Robin K.; Tossell, John A.

    1997-05-01

    An off-magic-angle spinning study of the nonassociated molecular solid, doubly15N-labeled 5-methyl-2-diazobenzenesulphonic acid hydrochloride (I) is reported. The validity of the off-magic-angle spinning approach under fast-spinning conditions is verified by average Hamiltonian theory. Ab initio SCF calculations were performed on the simpler molecule, C6H5N2+, to provide the shielding parameters, the dipolar coupling between the two nitrogen nuclei, and the electric field gradient existing at both the α-nitrogen and β-nitrogen sites. The calculated values are in good agreement with the shielding and effective dipolar coupling data elucidated in the present investigation, and with a previous study of the two singly15N-labeled isotopomers in which information concerning the electric field gradient at the α and β sites was deduced.

  18. Spin-locking and cross-polarization under magic-angle spinning of uniformly labeled solids.

    PubMed

    Hung, Ivan; Gan, Zhehong

    2015-07-01

    Spin-locking and cross-polarization under magic-angle spinning are investigated for uniformly (13)C and (15)N labeled solids. In particular, the interferences from chemical shift anisotropy, and (1)H heteronuclear and (13)C homonuclear dipolar couplings are identified. The physical origin of these interferences provides guidelines for selecting the best (13)C and (15)N polarization transfer rf fields. Optimal settings for both the zero- and double-quantum cross-polarization transfer mechanisms are recommended. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. The magic of social thought.

    PubMed

    Kalampalikis, Nikos

    2014-10-01

    Studying social thinking provides a promising field of investigation for the constitution of common knowledge in communication and action of historically and culturally situated groups. Its genealogy helps the understanding of the symbolic efficacy of social practices and their own operating collective logic. The English translation of a short version of Serge Moscovici's article on the new magical thinking allows a wider audience to gain access, for the first time, to a text that perfectly illustrates the currentness and relevance of the social psychology of knowledge. © The Author(s) 2014.

  20. Spectra, composition, and interactions of nuclei above 10 TeV using magnet-interferometric chambers

    NASA Technical Reports Server (NTRS)

    Gregory, J. C.; Takahashi, Y.

    1991-01-01

    Although the SCIN-MAGIC experiment has, like all ASTROMAG and most other Attached Payload experiments, been 'deselected' from Space Station, it is expected that ultimately such emulsion chambers will be flown on the Station. Some brief studies are described which were made in support of the design efforts for such a program being conducted at NASA Marshall.

  1. Relative suppression of magical thinking: a transcranial magnetic stimulation study.

    PubMed

    Bell, Vaughan; Reddy, Venu; Halligan, Peter; Kirov, George; Ellis, Hadyn

    2007-05-01

    The tendency to perceive meaning in noise (apophenia) has been linked to "magical thinking" (MT), a distinctive form of thinking associated with a range of normal cognitive styles, anomalous perceptual experiences and frank psychosis. Important aspects of MT include the propensity to imbue meaning or causality to events that might otherwise be considered coincidental. Structures in the lateral temporal lobes have been hypothesised to be involved in both the clinical and nonclinical aspects of MT. Accordingly, in this study we used single-pulse transcranial magnetic stimulation (TMS) to stimulate either the left or right lateral temporal areas, or the vertex, of 12 healthy participants (balanced for similar levels of MT, delusional ideation and temporal lobe disturbance) while they were required to indicate if they had "detected" pictures, claimed to be present by the experimenters, in visual noise. Relative to the vertex, TMS inhibition of the left lateral temporal area produced significant reduced tendency to report meaningful information, suggesting that left lateral temporal activation may be more important in MT and therefore producing and supporting anomalous beliefs and experiences. The effect cannot simply be explained by TMS induced cognitive slowing as reaction times were not affected.

  2. Brønsted acid sites based on penta-coordinated aluminum species

    NASA Astrophysics Data System (ADS)

    Wang, Zichun; Jiang, Yijiao; Lafon, Olivier; Trébosc, Julien; Duk Kim, Kyung; Stampfl, Catherine; Baiker, Alfons; Amoureux, Jean-Paul; Huang, Jun

    2016-12-01

    Zeolites and amorphous silica-alumina (ASA), which both provide Brønsted acid sites (BASs), are the most extensively used solid acid catalysts in the chemical industry. It is widely believed that BASs consist only of tetra-coordinated aluminum sites (AlIV) with bridging OH groups in zeolites or nearby silanols on ASA surfaces. Here we report the direct observation in ASA of a new type of BAS based on penta-coordinated aluminum species (AlV) by 27Al-{1H} dipolar-mediated correlation two-dimensional NMR experiments at high magnetic field under magic-angle spinning. Both BAS-AlIV and -AlV show a similar acidity to protonate probe molecular ammonia. The quantitative evaluation of 1H and 27Al sites demonstrates that BAS-AlV co-exists with BAS-AlIV rather than replaces it, which opens new avenues for strongly enhancing the acidity of these popular solid acids.

  3. Angular dependence of novel magnetic quantum oscillations in a quasi-two-dimensional multiband Fermi liquid with impurities

    NASA Astrophysics Data System (ADS)

    Bratkovsky, A. M.; Alexandrov, A. S.

    2002-03-01

    The semiclassical Lifshitz-Kosevich-type description is given for the angular dependence of quantum oscillations with combination frequencies in a multiband quasi-two-dimensional Fermi liquid with a constant number of electrons. The analytical expressions are found for the Dingle, thermal, spin, and amplitude (Yamaji) reduction factors of the novel combination harmonics, where the latter two strongly oscillate with the direction of the field [1]. At the magic angles those factors reduce to the purely two-dimensional expressions given earlier. The combination harmonics are suppressed in the presence of the nonquantized background states, and they decay exponentially faster with temperature and/or disorder compared to the standard harmonics, providing an additional tool for electronic structure determination. The theory is applied to Sr2RuO4. [1] A.M. Bratkovsky and A.S. Alexandrov, Phys. Rev. B 65, xxxx (2002); cond-mat/0104520.

  4. Characterization of Free Surface-Bound and Entrapped Water Environments in Poly(N-Isopropyl Acrylamide) Hydrogels via 1H HRMAS PFG NMR Spectroscopy

    DOE PAGES

    Alam, Todd Michael; Childress, Kimberly Kay; Pastoor, Kevin; ...

    2014-09-19

    We found that different water environments in poly(N-isopropyl acrylamide) (PNIPAAm) hydrogels are identified and characterized using 1H high resolution magic angle spinning (HRMAS) nuclear magnetic resonance (NMR). Local water environments corresponding to a “free” highly mobile species, along with waters showing restricted dynamics are resolved in these swollen hydro-gels. For photo-initiated polymerized PNIPAAm gels, an additional entrapped water species is observed. Spin–spin R 2 relaxation experiments support the argument of reduced mobility in the restricted and entrapped water species. Furthermore, by combining pulse field gradient techniques with HRMAS NMR it is possible to directly measure the self-diffusion rate for thesemore » different water environments. The behavior of the heterogeneous water environments through the lower critical solution temperature transition is described.« less

  5. Mechanisms of Dynamic Nuclear Polarization in Insulating Solids

    PubMed Central

    Can, T.V.; Ni, Q.Z.; Griffin, R.G.

    2015-01-01

    Dynamic nuclear polarization (DNP) is a technique used to enhance signal intensities in NMR experiments by transferring the high polarization of electrons to their surrounding nuclei. The past decade has witnessed a renaissance in the development of DNP, especially at high magnetic fields, and its application in several areas including biophysics, chemistry, structural biology and materials science. Recent technical and theoretical advances have expanded our understanding of established experiments: for example, the cross effect DNP in samples spinning at the magic angle. Furthermore, new experiments suggest that our understanding of the Overhauser effect and its applicability to insulating solids needs to be re-examined. In this article, we summarize important results of the past few years and provide quantum mechanical explanations underlying these results. We also discuss future directions of DNP and current limitations, including the problem of resolution in protein spectra recorded at 80–100 K. PMID:25797002

  6. Ground-state properties of neutron magic nuclei

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Saxena, G., E-mail: gauravphy@gmail.com; Kaushik, M.

    2017-03-15

    A systematic study of the ground-state properties of the entire chains of even–even neutron magic nuclei represented by isotones of traditional neutron magic numbers N = 8, 20, 40, 50, 82, and 126 has been carried out using relativistic mean-field plus Bardeen–Cooper–Schrieffer approach. Our present investigation includes deformation, binding energy, two-proton separation energy, single-particle energy, rms radii along with proton and neutron density profiles, etc. Several of these results are compared with the results calculated using nonrelativistic approach (Skyrme–Hartree–Fock method) along with available experimental data and indeed they are found with excellent agreement. In addition, the possible locations of themore » proton and neutron drip-lines, the (Z, N) values for the new shell closures, disappearance of traditional shell closures as suggested by the detailed analyzes of results are also discussed in detail.« less

  7. Virtual Field Trips.

    ERIC Educational Resources Information Center

    Walter, Virginia A.

    1997-01-01

    Virtual field trips can provide experiences beyond the reach of average K-12 students. Describes multimedia products for school use: Africa Trail, Dinosaur Hunter, Louvre Museum, Magic School Bus Explores the Rainforest, and Up to the Himalayas: Kingdoms in the Clouds and provides book and Internet connections for additional learning, highlighting…

  8. Recent on-beam tests of wide angle neutron polarization analysis with a 3He spin filter: Magic PASTIS on V20 at HZB

    NASA Astrophysics Data System (ADS)

    Babcock, E.; Salhi, Z.; Gainov, R.; Woracek, R.; Soltner, H.; Pistel, P.; Beule, F.; Bussmann, K.; Heynen, A.; Kämmerling, H.; Suxdorf, F.; Strobl, M.; Russina, M.; Voigt, J.; Ioffe, A.

    2017-06-01

    A complete XYZ polarization analysis solution is under development for the new thermal time of flight spectrometer TOPAS [1], to be operated in the coming east neutron guide hall at the MLZ. Polarization Analysis Studies on a Thermal Inelastic Spectrometer, commonly called PASTIS [2], is based on polarized 3He neutron spin filters and an XYZ field configuration for the sample environment and a polarization-preserving neutron guide field. The complete system was designed to provide adiabatic transport of the neutron polarization to the sample position while maintaining the homogeneity of the XYZ field. This system has now been tested on the polarized time-of-flight ESS test beam line V20 at HZB [3]. Down to the minimum wavelength of 1.6 Å on the instrument, the magnetic configuration worked ideally for neutron spin transport while giving full experimental freedom to change between the X, Y or Z field configuration. The 3He cell used was polarized at the 3He lab of the JCNS at the MLZ in Garching and transported to HZB in Berlin via car showing that such a transport is indeed feasible for such experiments. We present results of this test and the next steps forward.

  9. Graph theory and the Virasoro master equation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Obers, N.A.J.

    1991-01-01

    A brief history of affine Lie algebra, the Virasoro algebra and its culmination in the Virasoro master equation is given. By studying ansaetze of the master equation, the author obtains exact solutions and gains insight in the structure of large slices of affine-Virasoro space. He finds an isomorphism between the constructions in the ansatz SO(n){sub diag}, which is a set of unitary, generically irrational affine-Virasoro constructions on SO(n), and the unlabeled graphs of order n. On the one hand, the conformal constructions, are classified by the graphs, while, conversely, a group-theoretic and conformal field-theoretic identification is obtained for every graphmore » of graph theory. He also defines a class of magic Lie group bases in which the Virasoro master equation admits a simple metric ansatz {l brace}g{sub metric}{r brace}, whose structure is visible in the high-level expansion. When a magic basis is real on compact g, the corresponding g{sub metric} is a large system of unitary, generically irrational conformal field theories. Examples in this class include the graph-theory ansatz SO(n){sub diag} in the Cartesian basis of SO(n), and the ansatz SU(n){sub metric} in the Pauli-like basis of SU(n). Finally, he defines the sine-area graphs' of SU(n), which label the conformal field theories of SU(n){sub metric}, and he notes that, in similar fashion, each magic basis of g defines a generalized graph theory on g which labels the conformal field theories of g{sub metric}.« less

  10. Sleep Spindles Are Related to Schizotypal Personality Traits and Thalamic Glutamine/Glutamate in Healthy Subjects

    PubMed Central

    Lustenberger, Caroline; O’Gorman, Ruth L.; Pugin, Fiona; Tüshaus, Laura; Wehrle, Flavia; Achermann, Peter; Huber, Reto

    2015-01-01

    Background: Schizophrenia is a severe mental disorder affecting approximately 1% of the worldwide population. Yet, schizophrenia-like experiences (schizotypy) are very common in the healthy population, indicating a continuum between normal mental functioning and the psychosis found in schizophrenic patients. A continuum between schizotypy and schizophrenia would be supported if they share the same neurobiological origin. Two such neurobiological markers of schizophrenia are: (1) a reduction of sleep spindles (12–15 Hz oscillations during nonrapid eye movement sleep), likely reflecting deficits in thalamo-cortical circuits and (2) increased glutamine and glutamate (Glx) levels in the thalamus. Thus, this study aimed to investigate whether sleep spindles and Glx levels are related to schizotypal personality traits in healthy subjects. Methods: Twenty young male subjects underwent 2 all-night sleep electroencephalography recordings (128 electrodes). Sleep spindles were detected automatically. After those 2 nights, thalamic Glx levels were measured by magnetic resonance spectroscopy. Subjects completed a magical ideation scale to assess schizotypy. Results: Sleep spindle density was negatively correlated with magical ideation (r = −.64, P < .01) and thalamic Glx levels (r = −.70, P < .005). No correlation was found between Glx levels in the thalamus and magical ideation (r = .12, P > .1). Conclusions: The common relationship of sleep spindle density with schizotypy and thalamic Glx levels indicates a neurobiological overlap between nonclinical schizotypy and schizophrenia. Thus, sleep spindle density and magical ideation may reflect the anatomy and efficiency of the thalamo-cortical system that shows pronounced impairment in patients with schizophrenia. PMID:25074975

  11. New separators at the ATLAS facility

    NASA Astrophysics Data System (ADS)

    Back, Birger; Agfa Collaboration; Airis Team

    2015-10-01

    Two new separators are being built for the ATLAS facility. The Argonne Gas-Filled Analyzer (AGFA) is a novel design consisting of a single quadrupole and a multipole magnet that has both dipole and quadrupole field components. The design allows for placing Gammasphere at the target position while providing a solid angle of ~ 22 msr for capturing recoil products emitted at zero degrees. This arrangement enables studies of prompt gamma ray emission from weakly populated trans-fermium nuclei and those near the doubly-magic N = Z = 50 shell closure measured in coincidence with the recoils registered by AGFA. The Argonne In-flight Radioactive Ion Separator (AIRIS) is a magnetic chicane that will be installed immediately downstream of the last ATLAS cryostat and serve to separate radioactive ion beams generated in flight at an upstream high intensity production target. These beams will be further purified by a downstream RF sweeper and transported into a number of target stations including HELIOS, the Enge spectrograph, the FMA and Gammasphere. This talk will present the status of these two projects. This work was supported by the U.S. Department of Energy, Office of Nuclear Physics, under Contract No. DE-AC02-06CH11357.

  12. Further refinement of 17O TRAPDOR NMR methods for determining oxygen speciation in multi-component oxide glasses

    NASA Astrophysics Data System (ADS)

    LaComb, M.; Stebbins, J. F.

    2017-12-01

    Solid state nuclear magnetic resonance (NMR) spectroscopy has often been utilized to determine network speciation in oxide glasses, typically using NMR-active nuclides such as 11B, 27Al and 17O. High field strength magnets allow for visible separation between bridging (BO) and non-bridging oxygens (NBO) in 17O magic-angle spinning (MAS) NMR spectra, but many questions remain due to limited ability to directly observe NBO associated with silicon, boron or aluminum in ternary glass systems with MAS NMR techniques. Recent studies have utilized the combination of 17O{27Al} and 17O{11B} TRAnsfer of Population in DOuble-Resonance (TRAPDOR) NMR to attempt to separate out resonances for these different bridging and non-bridging oxygen species in multicomponent calcium aluminosilicate and aluminoborosilicate glasses and rare-earth aluminoborosilicates. With improved technology and better resolution of spectral components we were able to expand this study to a wider range of calcium aluminosilicate, aluminoborate and aluminoborosilicate glasses and further separate out resonances for both bridging and non-bridging oxygens coordinated with aluminum, boron and/or silicon cations in these glasses.

  13. Current-Voltage Characteristic of Nanosecond - Duration Relativistic Electron Beam

    NASA Astrophysics Data System (ADS)

    Andreev, Andrey

    2005-10-01

    The pulsed electron-beam accelerator SINUS-6 was used to measure current-voltage characteristic of nanosecond-duration thin annular relativistic electron beam accelerated in vacuum along axis of a smooth uniform metal tube immersed into strong axial magnetic field. Results of these measurements as well as results of computer simulations performed using 3D MAGIC code show that the electron-beam current dependence on the accelerating voltage at the front of the nanosecond-duration pulse is different from the analogical dependence at the flat part of the pulse. In the steady-state (flat) part of the pulse), the measured electron-beam current is close to Fedosov current [1], which is governed by the conservation law of an electron moment flow for any constant voltage. In the non steady-state part (front) of the pulse, the electron-beam current is higher that the appropriate, for a giving voltage, steady-state (Fedosov) current. [1] A. I. Fedosov, E. A. Litvinov, S. Ya. Belomytsev, and S. P. Bugaev, ``Characteristics of electron beam formed in diodes with magnetic insulation,'' Soviet Physics Journal (A translation of Izvestiya VUZ. Fizika), vol. 20, no. 10, October 1977 (April 20, 1978), pp.1367-1368.

  14. The nuclear shell model toward the drip lines

    NASA Astrophysics Data System (ADS)

    Poves, A.; Caurier, E.; Nowacki, F.; Sieja, K.

    2012-10-01

    We describe the 'islands of inversion' that occur when approaching the neutron drip line around the magic numbers N=20, N=28 and N=40 in the framework of the interacting shell model in very large valence spaces. We explain these configuration inversions (and the associated shape transitions) as the result of the competition between the spherical mean field (monopole) that favors magicity and the correlations (multipole) that favor deformed intruder states. We also show that the N=20 and N=28 islands are in reality a single one, which for the magnesium isotopes is limited by N=18 and N=32.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pilgrim, C. D.; Callahan, J. R.; Colla, C. A.

    Here, one-dimensional 27Al, 23Na Magic-Angle-Spinning (MAS) NMR and 27Al Multiple-Quantum Magic-Angle-Spinning NMR (MQMAS) measurements are reported for the δ-isomer of the Al 13 Keggin structure at high spinning speed and 14.1 T field. Values for the CQ and η parameters are on the same scale as those seen in other isomers of the Al 13 structure. Density functional theory (DFT) calculations are performed for comparison to the experimental fits using the B3PW91/6-31+G* and PBE0/6-31+G* levels of theory, with the Polarizable Continuum Model (PCM).

  16. Tissue Characterization with Quantitative High-Resolution Magic Angle Spinning Chemical Exchange Saturation Transfer Z-Spectroscopy.

    PubMed

    Zhou, Iris Yuwen; Fuss, Taylor L; Igarashi, Takahiro; Jiang, Weiping; Zhou, Xin; Cheng, Leo L; Sun, Phillip Zhe

    2016-11-01

    Chemical exchange saturation transfer (CEST) provides sensitive magnetic resonance (MR) contrast for probing dilute compounds via exchangeable protons, serving as an emerging molecular imaging methodology. CEST Z-spectrum is often acquired by sweeping radiofrequency saturation around bulk water resonance, offset by offset, to detect CEST effects at characteristic chemical shift offsets, which requires prolonged acquisition time. Herein, combining high-resolution magic angle spinning (HRMAS) with concurrent application of gradient and rf saturation to achieve fast Z-spectral acquisition, we demonstrated the feasibility of fast quantitative HRMAS CEST Z-spectroscopy. The concept was validated with phantoms, which showed excellent agreement with results obtained from conventional HRMAS MR spectroscopy (MRS). We further utilized the HRMAS Z-spectroscopy for fast ex vivo quantification of ischemic injury with rodent brain tissues after ischemic stroke. This method allows rapid and quantitative CEST characterization of biological tissues and shows potential for a host of biomedical applications.

  17. Gustave Flaubert, Charles Dickens, and Isaac Pulvermacher's "magic band".

    PubMed

    Waits, Robert K

    2013-01-01

    Around 1850, Isaac L. Pulvermacher (1815-1884) joined the ranks of so-called "galvanists" who had, for nearly a century, been touting the shocks and sparks of electricity as a miracle cure for all ills, including neurological complaints such as palsy and hemiplegia. The famed authors, Gustave Flaubert (1821-1880), in France, and Charles Dickens (1812-1870), in England, although contemporaries, apparently never met or corresponded. But during their lives, they both became aware of Pulvermacher and his patented Hydro-Electric Chains, claimed to impart vigor and cure nearly every complaint. Pulvermacher's chains made a cameo appearance in Madame Bovary (1857), Flaubert's controversial (and most successful) novel. Among Dickens's last letters (1870) was an order for I. L. Pulvermacher and Company's "magic band." Since the Victorian age, electrical and magnetic cures, for better or worse, continue to be products of both the medical profession and quackery. © 2013 Elsevier B.V. All rights reserved.

  18. Radiation response and basic dosimetric characterisation of the ‘Magic Plate’

    NASA Astrophysics Data System (ADS)

    Alrowaili, Z. A.; Lerch, M.; Petasecca, M.; Carolan, M.; Rosenfeld, A.

    2017-02-01

    Two Dimensional (2D) silicon diode arrays are often implemented in radiation therapy quality assurance (QA) applications due to their advantages such as: real-time operation (compared to the films), large dynamic range and small size (compared to ionization chambers). The Centre for Medical Radiation Physics, University of Wollongong has developed a multifunctional 2D silicon diode array known as the Magic Plate (MP) for real-time applications and is suitable as a transmission detector for photon flunce mapping (MPTM) or for in phantom dose mapping (MPDM). The paper focusses on the characterisation of the MPDM in terms of output factor and square field beam profiling in 6 MV, 10 MV and 18 MV clinical photon fields. We have found excellent agreement with three different ion chambers for all measured parameters with output factors agreeing within 1.2% and field profiles agreeing within 3% and/or 3mm. This work has important implications for the development of the MP when operating in transmission mapping mode.

  19. Abject Magic: Reasoning Madness in Justine Larbalestier's "Magic or Madness" Trilogy

    ERIC Educational Resources Information Center

    Potter, Troy

    2013-01-01

    This paper explores the representation of magic and madness in Justine Larbalestier's "Magic or Madness" trilogy (2005-2007). Throughout the series, magic is constructed as an abject and disabling force that threatens to disable magic-wielders, either through madness or death. Despite being represented as a ubiquitous force, the…

  20. Origins of magic: review of genetic and epigenetic effects.

    PubMed

    Ramagopalan, Sreeram V; Knight, Marian; Ebers, George C; Knight, Julian C

    2007-12-22

    To assess the evidence for a genetic basis to magic. Literature review. Harry Potter novels of J K Rowling. Muggles, witches, wizards, and squibs. Limited. Family and twin studies, magical ability, and specific magical skills. Magic shows strong evidence of heritability, with familial aggregation and concordance in twins. Evidence suggests magical ability to be a quantitative trait. Specific magical skills, notably being able to speak to snakes, predict the future, and change hair colour, all seem heritable. A multilocus model with a dominant gene for magic might exist, controlled epistatically by one or more loci, possibly recessive in nature. Magical enhancers regulating gene expressionmay be involved, combined with mutations at specific genes implicated in speech and hair colour such as FOXP2 and MCR1.

  1. 78 FR 25406 - Proposed Modification of Class E Airspace; Twin Falls, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ...) Global Positioning System (GPS) and the Instrument Landing System (ILS) or Localizer (LOC) standard... the earth. * * * * * ANM ID E5 Twin Falls, ID [Modified] Twin Falls Joslin Field-Magic Valley Regional...

  2. Chemical and carbon-13 cross-polarization magic-angle spinning nuclear magnetic resonance characterization of logyard fines from British Columbia.

    PubMed

    Preston, C M; Forrester, P D

    2004-01-01

    Phasing out beehive burners and rising costs for landfilling have increased the need to widen options for utilization of the smaller size fractions of woody wastes generated during log handling and sawmilling in British Columbia. We characterized several size classes of logyard fines up to 16 mm sampled from coastal and interior operations. Total C, total N, ash, and condensed tannin concentrations were consistent with properties derived largely from wood, with varying proportions of bark and mixing with mineral soil. Especially for < 3-mm fractions, the latter resulted in high ash contents that would make them unsuitable for fuel. Solid-state 13C cross-polarization magic-angle spinning (CPMAS) nuclear magnetic resonance (NMR) spectra were consistent with the chemical data, with high O-alkyl intensity and similarity to naturally occurring woody forest floor; no samples were high in aromatic or phenolic C. Aqueous extracts of two < 16-mm fines, which accounted for only a small proportion of the total C, were enriched in alkyl C and had low or undetectable tannins. Application to forest sites might cause short-term immobilization of N, but also might include possible longer-term benefits from reduction of N loss after harvesting and restoration of soil organic matter in degraded sites.

  3. The Magic of Balanced Groups: Educational Applications of Magic Squares

    ERIC Educational Resources Information Center

    Bosse, Michael J.; Nandakumar, N. R.; Ore, Melanie L.

    2007-01-01

    This paper provides students with many interesting observations regarding the nature of magic squares, magic rectangles, and quasi-magic squares and provides tools for teachers to group students into ability-balanced cooperative learning groups.

  4. Discovery of very high energy γ-ray emission from the blazar 1ES 0033+595 by the MAGIC telescopes

    DOE PAGES

    Aleksi , J.; Ansoldi, S.; Antonelli, L. A.; ...

    2014-11-11

    The number of known very high energy (VHE) blazars is ~50, which is very small in comparison to the number of blazars detected in other frequencies. This situation is a handicap for population studies of blazars, which emit about half of their luminosity in the γ-ray domain. Moreover, VHE blazars, if distant, allow for the study of the environment that the high-energy γ-rays traverse in their path towards the Earth, like the extragalactic background light (EBL) and the intergalactic magnetic field (IGMF), and hence they have a special interest for the astrophysics community. In this papaer, we present the firstmore » VHE detection of 1ES 0033+595 with a statistical significance of 5.5σ. The VHE emission of this object is constant throughout the MAGIC observations (2009 August and October), and can be parametrized with a power law with an integral flux above 150 GeV of (7.1 ± 1.3) × 10 -12 photons cm -2 s -1 and a photon index of (3.8 ± 0.7). We model its spectral energy distribution (SED) as the result of inverse Compton scattering of synchrotron photons. For the study of the SED, we used simultaneous optical R-band data from the KVA telescope, archival X-ray data by Swift as well as INTEGRAL, and simultaneous high-energy (HE, 300 MeV–10 GeV) γ-ray data from the Fermi Large Area Telescope (LAT) observatory. Using the empirical approach of Prandini et al. (2010) and the Fermi LAT and MAGIC spectra for this object, we estimate the redshift of this source to be 0.34 ± 0.08 ± 0.05. Also, this is a relevant result because this source is possibly one of the 10 most distant VHE blazars known to date, and with further (simultaneous) observations could play an important role in blazar population studies, as well as future constraints on the EBL and IGMF.« less

  5. Discovery of very high energy γ-ray emission from the blazar 1ES 0033+595 by the MAGIC telescopes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aleksi , J.; Ansoldi, S.; Antonelli, L. A.

    The number of known very high energy (VHE) blazars is ~50, which is very small in comparison to the number of blazars detected in other frequencies. This situation is a handicap for population studies of blazars, which emit about half of their luminosity in the γ-ray domain. Moreover, VHE blazars, if distant, allow for the study of the environment that the high-energy γ-rays traverse in their path towards the Earth, like the extragalactic background light (EBL) and the intergalactic magnetic field (IGMF), and hence they have a special interest for the astrophysics community. In this papaer, we present the firstmore » VHE detection of 1ES 0033+595 with a statistical significance of 5.5σ. The VHE emission of this object is constant throughout the MAGIC observations (2009 August and October), and can be parametrized with a power law with an integral flux above 150 GeV of (7.1 ± 1.3) × 10 -12 photons cm -2 s -1 and a photon index of (3.8 ± 0.7). We model its spectral energy distribution (SED) as the result of inverse Compton scattering of synchrotron photons. For the study of the SED, we used simultaneous optical R-band data from the KVA telescope, archival X-ray data by Swift as well as INTEGRAL, and simultaneous high-energy (HE, 300 MeV–10 GeV) γ-ray data from the Fermi Large Area Telescope (LAT) observatory. Using the empirical approach of Prandini et al. (2010) and the Fermi LAT and MAGIC spectra for this object, we estimate the redshift of this source to be 0.34 ± 0.08 ± 0.05. Also, this is a relevant result because this source is possibly one of the 10 most distant VHE blazars known to date, and with further (simultaneous) observations could play an important role in blazar population studies, as well as future constraints on the EBL and IGMF.« less

  6. Self-similar Theory of Wind-driven Sea

    NASA Astrophysics Data System (ADS)

    Zakharov, V. E.

    2015-12-01

    More than two dozens field experiments performed in the ocean and on the lakes show that the fetch-limited growth of dimensionless energy and dimensionless peak frequency is described by powerlike functions of the dimensionless fetch. Moreover, the exponents of these two functions are connected with a proper accuracy by the standard "magic relation", 10q-2p=1. Recent massive numerical experiments as far as experiments in wave tanks also confirm this magic relation. All these experimental facts can be interpreted in a framework of the following simple theory. The wind-driven sea is described by the "conservative" Hasselmann kinetic equation. The source terms, wind input and white-capping dissipation, play a secondary role in comparison with the nonlinear term Snl that is responsible for the four-wave resonant interaction. This equation has four-parameter family of self-similar solutions. The magic relation holds for all numbers of this family. This fact gives strong hope that development of self-consistent analytic theory of wind-driven sea is quite realizable task.

  7. Magic angle spinning NMR with metallized rotors as cylindrical microwave resonators.

    PubMed

    Scott, Faith J; Sesti, Erika L; Choi, Eric J; Laut, Alexander J; Sirigiri, Jagadishwar R; Barnes, Alexander B

    2018-04-19

    We introduce a novel design for millimeter wave electromagnetic structures within magic angle spinning (MAS) rotors. In this demonstration, a copper coating is vacuum deposited onto the outside surface of a sapphire rotor at a thickness of 50 nm. This thickness is sufficient to reflect 197-GHz microwaves, yet not too thick as to interfere with radiofrequency fields at 300 MHz or prevent sample spinning due to eddy currents. Electromagnetic simulations of an idealized rotor geometry show a microwave quality factor of 148. MAS experiments with sample rotation frequencies of ω r /2π = 5.4 kHz demonstrate that the drag force due to eddy currents within the copper does not prevent sample spinning. Spectra of sodium acetate show resolved 13 C J-couplings of 60 Hz and no appreciable broadening between coated and uncoated sapphire rotors, demonstrating that the copper coating does not prevent shimming and high-resolution nuclear magnetic resonance spectroscopy. Additionally, 13 C Rabi nutation curves of ω 1 /2π = 103 kHz for both coated and uncoated rotors indicate no detrimental impact of the copper coating on radio frequency coupling of the nuclear spins to the sample coil. We present this metal coated rotor as a first step towards an MAS resonator. MAS resonators are expected to have a significant impact on developments in electron decoupling, pulsed dynamic nuclear polarization (DNP), room temperature DNP, DNP with low-power microwave sources, and electron paramagnetic resonance detection. Copyright © 2018 John Wiley & Sons, Ltd.

  8. Adjustable Spin-Spin Interaction with 171Yb+ ions and Addressing of a Quantum Byte

    NASA Astrophysics Data System (ADS)

    Wunderlich, Christof

    2015-05-01

    Trapped atomic ions are a well-advanced physical system for investigating fundamental questions of quantum physics and for quantum information science and its applications. When contemplating the scalability of trapped ions for quantum information science one notes that the use of laser light for coherent operations gives rise to technical and also physical issues that can be remedied by replacing laser light by microwave (MW) and radio-frequency (RF) radiation employing suitably modified ion traps. Magnetic gradient induced coupling (MAGIC) makes it possible to coherently manipulate trapped ions using exclusively MW and RF radiation. After introducing the general concept of MAGIC, I shall report on recent experimental progress using 171Yb+ ions, confined in a suitable Paul trap, as effective spin-1/2 systems interacting via MAGIC. Entangling gates between non-neighbouring ions will be presented. The spin-spin coupling strength is variable and can be adjusted by variation of the secular trap frequency. In general, executing a quantum gate with a single qubit, or a subset of qubits, affects the quantum states of all other qubits. This reduced fidelity of the whole quantum register may preclude scalability. We demonstrate addressing of individual qubits within a quantum byte (eight qubits interacting via MAGIC) using MW radiation and measure the error induced in all non-addressed qubits (cross-talk) associated with the application of single-qubit gates. The measured cross-talk is on the order 10-5 and therefore below the threshold commonly agreed sufficient to efficiently realize fault-tolerant quantum computing. Furthermore, experimental results on continuous and pulsed dynamical decoupling (DD) for protecting quantum memories and quantum gates against decoherence will be briefly discussed. Finally, I report on using continuous DD to realize a broadband ultrasensitive single-atom magnetometer.

  9. 71Ga-77Se connectivities and proximities in gallium selenide crystal and glass probed by solid-state NMR

    NASA Astrophysics Data System (ADS)

    Nagashima, Hiroki; Trébosc, Julien; Calvez, Laurent; Pourpoint, Frédérique; Mear, François; Lafon, Olivier; Amoureux, Jean-Paul

    2017-09-01

    We introduce two-dimensional (2D) 71Ga-77Se through-bond and through-space correlation experiments. Such correlations are achieved using (i) the J-mediated Refocused Insensitive Nuclei Enhanced by Polarization Transfer (J-RINEPT) method with 71Ga excitation and 77Se Carr-Purcell-Meiboon-Gill (CPMG) detection, as well as (ii) the J- or dipolar-mediated Hetero-nuclear Multiple-Quantum Correlation (J- or D-HMQC) schemes with 71Ga excitation and quadrupolar CPMG (QCPMG) detection. These methods are applied to the crystalline β-Ga2Se3 and the 0.2Ga2Se3-0.8GeSe2 glass. Such glass leads to a homogeneous and reproducible glass-ceramic, which is a good alternative to single-crystalline Ge and polycrystalline ZnSe materials for making lenses transparent in the IR range for thermal imaging applications. We show that 2D 71Ga-77Se correlation experiments allow resolving the 77Se signals of molecular units, which are not resolved in the 1D 77Se CPMG spectrum. Additionally, the build-up curves of the J-RINEPT and the J-HMQC experiments allow the estimate of the 71Ga-77Se J-couplings via one and three-bonds in the three-dimensional network of β-Ga2Se3. Furthermore, these build-up curves show that the one-bond 1J71Ga-77Se couplings in the 0.2Ga2Se3-0.8GeSe2 glass are similar to those measured for β-Ga2Se3. We also report 2D 71Ga Satellite Transition Magic-Angle Spinning (STMAS) spectrum of β-Ga2Se3 using QCPMG detection at high magnetic field and high Magic-Angle Spinning frequency using large radio frequency field. Such spectrum allows separating the signal of β-Ga2Se3 and that of an impurity.

  10. Combining Nuclear Magnetic Resonance Spectroscopy and Density Functional Theory Calculations to Characterize Carvedilol Polymorphs.

    PubMed

    Rezende, Carlos A; San Gil, Rosane A S; Borré, Leandro B; Pires, José Ricardo; Vaiss, Viviane S; Resende, Jackson A L C; Leitão, Alexandre A; De Alencastro, Ricardo B; Leal, Katia Z

    2016-09-01

    The experiments of carvedilol form II, form III, and hydrate by (13)C and (15)N cross-polarization magic-angle spinning (CP MAS) are reported. The GIPAW (gauge-including projector-augmented wave) method from DFT (density functional theory) calculations was used to simulate (13)C and (15)N chemical shifts. A very good agreement was found for the comparison between the global results of experimental and calculated nuclear magnetic resonance (NMR) chemical shifts for carvedilol polymorphs. This work aims a comprehensive understanding of carvedilol crystalline forms employing solution and solid-state NMR as well as DFT calculations. Copyright © 2016. Published by Elsevier Inc.

  11. The investigation of the effect of thermal treatment on bentonites from Turkey with Fourier transform infrared and solid state nuclear magnetic resonance spectroscopic methods.

    PubMed

    Erdoğan Alver, Burcu; Alver, Ozgür

    2012-08-01

    There is a great deal of interest in the building industry in burned clays for production of building materials. Therefore, the effect of heat treatment on natural bentonite from Turkey was investigated by Fourier transform infrared (FT-IR) between the region of 4000-400cm(-1) and (29)Si, (27)Al magic angle spinning nuclear magnetic resonance (MAS NMR) measurement techniques at various temperatures between 200 and 700°C for 2h. The structural changes were also investigated upon heat treatment. Copyright © 2012 Elsevier B.V. All rights reserved.

  12. 27Al MQMAS of the δ-Al 13-Keggin

    DOE PAGES

    Pilgrim, C. D.; Callahan, J. R.; Colla, C. A.; ...

    2017-01-20

    Here, one-dimensional 27Al, 23Na Magic-Angle-Spinning (MAS) NMR and 27Al Multiple-Quantum Magic-Angle-Spinning NMR (MQMAS) measurements are reported for the δ-isomer of the Al 13 Keggin structure at high spinning speed and 14.1 T field. Values for the CQ and η parameters are on the same scale as those seen in other isomers of the Al 13 structure. Density functional theory (DFT) calculations are performed for comparison to the experimental fits using the B3PW91/6-31+G* and PBE0/6-31+G* levels of theory, with the Polarizable Continuum Model (PCM).

  13. Expertise among professional magicians: an interview study.

    PubMed

    Rissanen, Olli; Pitkänen, Petteri; Juvonen, Antti; Kuhn, Gustav; Hakkarainen, Kai

    2014-01-01

    The purpose of the present investigation was to analyse interviews of highly regarded Finnish magicians. Social network analysis (N = 120) was used to identify Finland's most highly regarded magicians (N = 16). The selected participants' careers in professional magic and various aspects of their professional conduct were examined by relying on semi-structured interviews. The results revealed that cultivation of professional level competence in magic usually requires an extensive period of time compared with other domains of expertise. Magic is a unique performing art and it differs from other professions focusing on deceiving the audience. A distinctive feature of magical expertise is that the process takes place entirely through informal training supported by communities of magical practitioners. Three interrelated aspects of magical activity were distinguished: magic tricks, performance, and audience. Although magic tricks constitute a central aspect of magic activity, the participants did not talk about their tricks extensively; this is in accordance with the secretive nature of magic culture. The interviews revealed that a core aspect of the magicians' activity is performance in front of an audience that repeatedly validates competence cultivated through years of practice. The interviewees reported investing a great deal of effort in planning, orchestrating, and reflecting on their performances. Close interaction with the audience plays an important role in most interviewees' activity. Many participants put a great deal of effort in developing novel magic tricks. It is common to borrow magic effects from fellow magicians and develop novel methods of implementation. Because magic tricks or programs are not copyrighted, many interviewees considered "stealing" an unacceptable and unethical aspect of magical activity. The interviewees highlighted the importance of personality and charisma in the successful pursuit of magic activity.

  14. Expertise among professional magicians: an interview study

    PubMed Central

    Rissanen, Olli; Pitkänen, Petteri; Juvonen, Antti; Kuhn, Gustav; Hakkarainen, Kai

    2014-01-01

    The purpose of the present investigation was to analyse interviews of highly regarded Finnish magicians. Social network analysis (N = 120) was used to identify Finland's most highly regarded magicians (N = 16). The selected participants' careers in professional magic and various aspects of their professional conduct were examined by relying on semi-structured interviews. The results revealed that cultivation of professional level competence in magic usually requires an extensive period of time compared with other domains of expertise. Magic is a unique performing art and it differs from other professions focusing on deceiving the audience. A distinctive feature of magical expertise is that the process takes place entirely through informal training supported by communities of magical practitioners. Three interrelated aspects of magical activity were distinguished: magic tricks, performance, and audience. Although magic tricks constitute a central aspect of magic activity, the participants did not talk about their tricks extensively; this is in accordance with the secretive nature of magic culture. The interviews revealed that a core aspect of the magicians' activity is performance in front of an audience that repeatedly validates competence cultivated through years of practice. The interviewees reported investing a great deal of effort in planning, orchestrating, and reflecting on their performances. Close interaction with the audience plays an important role in most interviewees' activity. Many participants put a great deal of effort in developing novel magic tricks. It is common to borrow magic effects from fellow magicians and develop novel methods of implementation. Because magic tricks or programs are not copyrighted, many interviewees considered “stealing” an unacceptable and unethical aspect of magical activity. The interviewees highlighted the importance of personality and charisma in the successful pursuit of magic activity. PMID:25566156

  15. Evaluation Field Building in South Asia: Insights from the Rear View Mirror

    ERIC Educational Resources Information Center

    Grob, George F.

    2010-01-01

    The author enjoyed reading Katharine Hay's ambitious and humbling visions for evaluation field building in South Asia. She has successfully positioned herself on a high mountain with a wonderful set of binoculars that enable her to see the entire evaluation landscape of South Asia. She magically sees and describes significant historical forces and…

  16. Hartmann-Hahn 2D-map to optimize the RAMP-CPMAS NMR experiment for pharmaceutical materials.

    PubMed

    Suzuki, Kazuko; Martineau, Charlotte; Fink, Gerhard; Steuernagel, Stefan; Taulelle, Francis

    2012-02-01

    Cross polarization-magic angle spinning (CPMAS) is the most used experiment for solid-state NMR measurements in the pharmaceutical industry, with the well-known variant RAMP-CPMAS its dominant implementation. The experimental work presented in this contribution focuses on the entangled effects of the main parameters of such an experiment. The shape of the RAMP-CP pulse has been considered as well as the contact time duration, and a particular attention also has been devoted to the radio-frequency (RF) field inhomogeneity. (13)C CPMAS NMR spectra have been recorded with a systematic variation of (13)C and (1)H constant radiofrequency field pair values and represented as a Hartmann-Hahn matching two-dimensional map. Such a map yields a rational overview of the intricate optimal conditions necessary to achieve an efficient CP magnetization transfer. The map also highlights the effects of sweeping the RF by the RAMP-CP pulse on the number of Hartmann-Hahn matches crossed and how RF field inhomogeneity helps in increasing the CP efficiency by using a larger fraction of the sample. In the light of the results, strategies for optimal RAMP-CPMAS measurements are suggested, which lead to a much higher efficiency than constant amplitude CP experiment. Copyright © 2012 John Wiley & Sons, Ltd.

  17. MAGIC database and interfaces: an integrated package for gene discovery and expression.

    PubMed

    Cordonnier-Pratt, Marie-Michèle; Liang, Chun; Wang, Haiming; Kolychev, Dmitri S; Sun, Feng; Freeman, Robert; Sullivan, Robert; Pratt, Lee H

    2004-01-01

    The rapidly increasing rate at which biological data is being produced requires a corresponding growth in relational databases and associated tools that can help laboratories contend with that data. With this need in mind, we describe here a Modular Approach to a Genomic, Integrated and Comprehensive (MAGIC) Database. This Oracle 9i database derives from an initial focus in our laboratory on gene discovery via production and analysis of expressed sequence tags (ESTs), and subsequently on gene expression as assessed by both EST clustering and microarrays. The MAGIC Gene Discovery portion of the database focuses on information derived from DNA sequences and on its biological relevance. In addition to MAGIC SEQ-LIMS, which is designed to support activities in the laboratory, it contains several additional subschemas. The latter include MAGIC Admin for database administration, MAGIC Sequence for sequence processing as well as sequence and clone attributes, MAGIC Cluster for the results of EST clustering, MAGIC Polymorphism in support of microsatellite and single-nucleotide-polymorphism discovery, and MAGIC Annotation for electronic annotation by BLAST and BLAT. The MAGIC Microarray portion is a MIAME-compliant database with two components at present. These are MAGIC Array-LIMS, which makes possible remote entry of all information into the database, and MAGIC Array Analysis, which provides data mining and visualization. Because all aspects of interaction with the MAGIC Database are via a web browser, it is ideally suited not only for individual research laboratories but also for core facilities that serve clients at any distance.

  18. CP/MAS /sup 13/C NMR spectroscopic study of chlorophyll a in the solid state

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brown, C.E.; Spencer, R.B.; Burger, V.T.

    1983-09-01

    Solid-state cross-polarization, magic-angle sample spinning carbon-13 nuclear magnetic resonance spectra have been recorded on chlorophyll a- water aggregates, methyl pyrochlorophyllide a and methyl pyropheophorbide a (derivatives that lack a phytyl chain). Spectra have also been collected under a decoupling regime in which resonances of certain hydrogen-bearing carbon atoms are suppressed. These observations are used to assign the solid state spectra.

  19. Creating a FIESTA (Framework for Integrated Earth Science and Technology Applications) with MagIC

    NASA Astrophysics Data System (ADS)

    Minnett, R.; Koppers, A. A. P.; Jarboe, N.; Tauxe, L.; Constable, C.

    2017-12-01

    The Magnetics Information Consortium (https://earthref.org/MagIC) has recently developed a containerized web application to considerably reduce the friction in contributing, exploring and combining valuable and complex datasets for the paleo-, geo- and rock magnetic scientific community. The data produced in this scientific domain are inherently hierarchical and the communities evolving approaches to this scientific workflow, from sampling to taking measurements to multiple levels of interpretations, require a large and flexible data model to adequately annotate the results and ensure reproducibility. Historically, contributing such detail in a consistent format has been prohibitively time consuming and often resulted in only publishing the highly derived interpretations. The new open-source (https://github.com/earthref/MagIC) application provides a flexible upload tool integrated with the data model to easily create a validated contribution and a powerful search interface for discovering datasets and combining them to enable transformative science. MagIC is hosted at EarthRef.org along with several interdisciplinary geoscience databases. A FIESTA (Framework for Integrated Earth Science and Technology Applications) is being created by generalizing MagIC's web application for reuse in other domains. The application relies on a single configuration document that describes the routing, data model, component settings and external services integrations. The container hosts an isomorphic Meteor JavaScript application, MongoDB database and ElasticSearch search engine. Multiple containers can be configured as microservices to serve portions of the application or rely on externally hosted MongoDB, ElasticSearch, or third-party services to efficiently scale computational demands. FIESTA is particularly well suited for many Earth Science disciplines with its flexible data model, mapping, account management, upload tool to private workspaces, reference metadata, image galleries, full text searches and detailed filters. EarthRef's Seamount Catalog of bathymetry and morphology data, EarthRef's Geochemical Earth Reference Model (GERM) databases, and Oregon State University's Marine and Geology Repository (http://osu-mgr.org) will benefit from custom adaptations of FIESTA.

  20. Off-resonance NOVEL

    NASA Astrophysics Data System (ADS)

    Jain, Sheetal K.; Mathies, Guinevere; Griffin, Robert G.

    2017-10-01

    Dynamic nuclear polarization (DNP) is theoretically able to enhance the signal in nuclear magnetic resonance (NMR) experiments by a factor γe/γn, where γ 's are the gyromagnetic ratios of an electron and a nuclear spin. However, DNP enhancements currently achieved in high-field, high-resolution biomolecular magic-angle spinning NMR are well below this limit because the continuous-wave DNP mechanisms employed in these experiments scale as ω0-n where n ˜ 1-2. In pulsed DNP methods, such as nuclear orientation via electron spin-locking (NOVEL), the DNP efficiency is independent of the strength of the main magnetic field. Hence, these methods represent a viable alternative approach for enhancing nuclear signals. At 0.35 T, the NOVEL scheme was demonstrated to be efficient in samples doped with stable radicals, generating 1H NMR enhancements of ˜430. However, an impediment in the implementation of NOVEL at high fields is the requirement of sufficient microwave power to fulfill the on-resonance matching condition, ω0I = ω1S, where ω0I and ω1S are the nuclear Larmor and electron Rabi frequencies, respectively. Here, we exploit a generalized matching condition, which states that the effective Rabi frequency, ω1S e f f, matches ω0I. By using this generalized off-resonance matching condition, we generate 1H NMR signal enhancement factors of 266 (˜70% of the on-resonance NOVEL enhancement) with ω1S/2π = 5 MHz. We investigate experimentally the conditions for optimal transfer of polarization from electrons to 1H both for the NOVEL mechanism and the solid-effect mechanism and provide a unified theoretical description for these two historically distinct forms of DNP.

  1. Spin-locking of half-integer quadrupolar nuclei in nuclear magnetic resonance of solids: creation and evolution of coherences.

    PubMed

    Ashbrook, Sharon E; Wimperis, Stephen

    2004-02-08

    Spin-locking of half-integer quadrupolar nuclei, such as 23Na (I=3/2) and 27Al (I=5/2), is of renewed interest owing to the development of variants of the multiple-quantum and satellite-transition magic angle spinning (MAS) nuclear magnetic resonance experiments that either utilize spin-locking directly or offer the possibility that spin-locked states may arise. However, the large magnitude and, under MAS, the time dependence of the quadrupolar interaction often result in complex spin-locking phenomena that are not widely understood. Here we show that, following the application of a spin-locking pulse, a variety of coherence transfer processes occur on a time scale of approximately 1/omegaQ before the spin system settles down into a spin-locked state which may itself be time dependent if MAS is performed. We show theoretically for both spin I=3/2 and 5/2 nuclei that the spin-locked state created by this initial rapid dephasing typically consists of a variety of single- and multiple-quantum coherences and nonequilibrium population states and we discuss the subsequent evolution of these under MAS. In contrast to previous work, we consider spin-locking using a wide range of radio frequency field strengths, i.e., a range that covers both the "strong-field" (omega1 > omegaQPAS and "weak-field" (omega1 < omegaQPAS limits. Single- and multiple-quantum filtered spin-locking experiments on NaNO2, NaNO3, and Al(acac)3, under both static and MAS conditions, are used to illustrate and confirm the results of the theoretical discussion.

  2. A systematic study of superheavy nuclei for Z = 114 and beyond using the relativistic mean field approach

    NASA Astrophysics Data System (ADS)

    Patra, S. K.; Wu, Cheng-Li; Praharaj, C. R.; Gupta, Raj K.

    1999-05-01

    We have studied the structural properties of even-even, neutron deficient, Z = 114-126, superheavy nuclei in the mass region A ˜ 270-320, using an axially deformed relativistic mean field model. The calculations are performed with three parameter sets (NL1, TM1 and NL-SH), in order to see the dependence of the structural properties on the force used. The calculated ground state shapes are found to be parameter dependent. For some parameter sets, many of the nuclei are degenerate in their ground state configuration. Special attention is given to the investigation of the magic structures (spherical shell closures) in the superheavy region. We find that some known magic numbers are absent and new closed shells are predicted. Large shell gaps appear at Z = 80, 92, (114), 120 and 138, N = 138, (164), (172), 184, (198), (228) and 258, irrespective of the parameter sets used. The numbers in parenthesis are those which correspond to relatively smaller gaps. The existence of new magic numbers in the valley of superheavy elements is discussed. It is suggested that nuclei around Z = 114 and N = 164 ˜ 172 could be considered as candidates for the next search of superheavy nuclei. The existence of superheavy islands around Z = 120 and N = 172 or N = 184 double shell closure is also discussed.

  3. Solid-Cryogen Cooling Technique for Superconducting Magnets of NMR and MRI

    NASA Astrophysics Data System (ADS)

    Iwasa, Yukikazu; Bascuñán, Juan; Hahn, Seungyong; Park, Dong Keun

    This paper describes a solid-cryogen cooling technique currently being developed at the M.I.T. Francis Bitter Magnet Laboratory for application to superconducting magnets of NMR and MRI. The technique is particularly appropriate for "dry" magnets that do not rely on liquid cryogen, e.g., liquid helium (LHe), as their primary cooling sources. In addition, the advantages of a cryocirculator (a combination of a cryocooler and a working fluid circulator) over a cryocooler as the primary cooling source for dry magnets are described. The four magnets described here, all incorporating this cooling technique described and currently being developed at the FBML, are: 1) a solid-nitrogen (SN2)-cooled Nb3Sn 500-MHz/200-mm MRI magnet with an operating temperature range between 4.2 K (nominal) and 6.0 K (maximum with its primary cooling source off); 2) an SN2-cooled MgB2 0.5-T/800-mm MRI magnet, 1015 K; 3) an SN2-cooled compact YBCO "annulus" 100-MHz/9-mm NMR magnet, 10-15 K; 4) an SN2-cooled 1.5T/75-mm NbTi magnet for slow magic-angle-spinning NMR/MRI, 4.5-5.5 K.

  4. Application of a Resource Theory for Magic States to Fault-Tolerant Quantum Computing.

    PubMed

    Howard, Mark; Campbell, Earl

    2017-03-03

    Motivated by their necessity for most fault-tolerant quantum computation schemes, we formulate a resource theory for magic states. First, we show that robustness of magic is a well-behaved magic monotone that operationally quantifies the classical simulation overhead for a Gottesman-Knill-type scheme using ancillary magic states. Our framework subsequently finds immediate application in the task of synthesizing non-Clifford gates using magic states. When magic states are interspersed with Clifford gates, Pauli measurements, and stabilizer ancillas-the most general synthesis scenario-then the class of synthesizable unitaries is hard to characterize. Our techniques can place nontrivial lower bounds on the number of magic states required for implementing a given target unitary. Guided by these results, we have found new and optimal examples of such synthesis.

  5. Singularities in the lineshape of a second-order perturbed quadrupolar nucleus. The magic-angle spinning case.

    PubMed

    Field, Timothy R; Bain, Alex D

    2014-01-01

    For a nucleus with a half-integral spin and a strong quadrupole coupling, the central transition (from magnetic quantum number -1/2 to +1/2) in the spectrum shows a characteristic lineshape. By strong coupling, we mean an interaction strong enough so that second-order perturbation theory is needed, yet still sufficient. The spectrum of a static sample is well-known and the magic-angle-spinning (MAS spectrum) is different, but still can be calculated. The important features of both these spectra are singularities and steps in the lineshape, since these are the main tools in fitting the calculated spectrum to experimental data. A useful tool in this investigation is a plot of the frequency as a function of orientation over the surface of the unit sphere. These plots have maxima, minima and saddle points, and these correspond to the features of the spectrum. We used these plots to define both the positions and derive new formulae for the heights of the features and we now extend this to the magic-angle spinning case. For the first time, we identify the orientations corresponding to the features of the MAS spectra and derive formulae for the heights. We then compare the static and MAS cases and show the relationships between the features in the two spectra. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. [Nature as magician: on the Paracelsus heritage of modern medicine].

    PubMed

    Heinz, Schott

    2010-01-01

    The concept of "natural magic" (magia naturalis) was very important for medicine and natural science of the early modem period. It stressed a new scientific world view (Weltanschauung) moving away from "supernatural" (superstitious) perceptions and trying to explain all spectacular marvels as results of natural processes. So, Nature (natura), often personified as a female figure, was considered as a (female) magician. Physicians and naturalists should learn from her art to become able to imitate and accomplish her work. In particular this concept was relevant for the al-chemical and magical medicine as the writings of PARACELSUS show. He perceived like many of his contemporaries Nature as a servant of God producing all things according to his will supplying them with "signatures" indicating the scholar (philosophus) their hidden ("natural") powers. The iconography and emblematics of the early modem period--partly directly influenced by the paracelsian thinking--illustrate in different ways the concept of natural magic. Especially the hierarchy God--Nature--Human and the phenomena of light representing divine wisdom and power were imagined. It is remarkable, that also during the enlightenment in regard to artificial electricity and animal magnetism analogous ideas appeared in connection with the light imagery (ether, fluidum). Finally, the romantic natural philosophy dealt with them intensively, and they stimulated not only natural scientific respectively (neuro) physiological, but also psychological (experimental) research.

  7. Angle-dependent quantum Otto heat engine based on coherent dipole-dipole coupling

    NASA Astrophysics Data System (ADS)

    Su, Shan-He; Luo, Xiao-Qing; Chen, Jin-Can; Sun, Chang-Pu

    2016-08-01

    Electromagnetic interactions between molecules or within a molecule have been widely observed in biological systems and exhibit broad application for molecular structural studies. Quantum delocalization of molecular dipole moments has inspired researchers to explore new avenues to utilize this physical effect for energy harvesting devices. Herein, we propose a simple model of the angle-dependent quantum Otto heat engine which seeks to facilitate the conversion of heat to work. Unlike previous studies, the adiabatic processes are accomplished by varying only the directions of the magnetic field. We show that the heat engine continues to generate power when the angle relative to the vector r joining the centres of coupled dipoles departs from the magic angle θm where the static coupling vanishes. A significant improvement in the device performance has to be attributed to the presence of the quantum delocalized levels associated with the coherent dipole-dipole coupling. These results obtained may provide a promising model for the biomimetic design and fabrication of quantum energy generators.

  8. Scalable designs for quasiparticle-poisoning-protected topological quantum computation with Majorana zero modes

    NASA Astrophysics Data System (ADS)

    Karzig, Torsten; Knapp, Christina; Lutchyn, Roman M.; Bonderson, Parsa; Hastings, Matthew B.; Nayak, Chetan; Alicea, Jason; Flensberg, Karsten; Plugge, Stephan; Oreg, Yuval; Marcus, Charles M.; Freedman, Michael H.

    2017-06-01

    We present designs for scalable quantum computers composed of qubits encoded in aggregates of four or more Majorana zero modes, realized at the ends of topological superconducting wire segments that are assembled into superconducting islands with significant charging energy. Quantum information can be manipulated according to a measurement-only protocol, which is facilitated by tunable couplings between Majorana zero modes and nearby semiconductor quantum dots. Our proposed architecture designs have the following principal virtues: (1) the magnetic field can be aligned in the direction of all of the topological superconducting wires since they are all parallel; (2) topological T junctions are not used, obviating possible difficulties in their fabrication and utilization; (3) quasiparticle poisoning is abated by the charging energy; (4) Clifford operations are executed by a relatively standard measurement: detection of corrections to quantum dot energy, charge, or differential capacitance induced by quantum fluctuations; (5) it is compatible with strategies for producing good approximate magic states.

  9. ["The multiple science instructional curious artist". Alchemy, folk magic and folk medicine in baroque home reference books].

    PubMed

    Priesner, Claus

    2011-01-01

    Germany's Hausväterliteratur, the "literature of the fathers of the houses," was once a popular genre but today is seldom studied. Roughly, this literature, as its name suggests, comprises books on the proper keeping of noble households and mansions. Interestingly, besides the content which one might expect in such books, the organization of personnel, the arrangement of festivities, discussions of the various branches of technical skills, economic advice and the whole field of agriculture, fishing and hunting, these books also contain remarkably large amounts of information directly connected with magic and an associated popular medicine (Volksmedizin). This medicine involved treatment administered mostly by laywomen instead of regular physicians and was based not just upon traditional medical knowledge per se but also upon magical practices. Also found in such texts are alchemical ideas and recipes. This means that despite the fact that such books were written and published in the 17th and early 18th century, the Age of Enlightenment, conceptions found in them are still deeply rooted in older intellectual currents, in Medieval and Renaissance thinking. The present study examines examples of alchemical, magical and popular medical ideas in three such works and seeks to explain how pre-enlightenment ideas and thought could maintain such an influential place in the intellectual world of a later time dominated by other philosophies.

  10. 77 FR 58416 - Large Scale Networking (LSN); Middleware and Grid Interagency Coordination (MAGIC) Team

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ... Coordination (MAGIC) Team AGENCY: The Networking and Information Technology Research and Development (NITRD.... Dates/Location: The MAGIC Team meetings are held on the first Wednesday of each month, 2:00-4:00pm, at... participation is available for each meeting. Please reference the MAGIC Team Web site for updates. Magic Web...

  11. 78 FR 70076 - Large Scale Networking (LSN)-Middleware and Grid Interagency Coordination (MAGIC) Team

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-22

    ... Coordination (MAGIC) Team AGENCY: The Networking and Information Technology Research and Development (NITRD... MAGIC Team meetings are held on the first Wednesday of each month, 2:00-4:00 p.m., at the National... for each meeting. Please reference the MAGIC Team Web site for updates. Magic Web site: The agendas...

  12. Synthesis and evaluation of nitroxide-based oligoradicals for low-temperature dynamic nuclear polarization in solid state NMR

    PubMed Central

    Yau, Wai-Ming; Thurber, Kent R.; Tycko, Robert

    2014-01-01

    We describe the synthesis of new nitroxide-based biradical, triradical, and tetraradical compounds and the evaluation of their performance as paramagnetic dopants in dynamic nuclear polarization (DNP) experiments in solid state nuclear magnetic resonance (NMR) spectroscopy with magic-angle spinning (MAS). Under our experimental conditions, which include temperatures in the 25–30 K range, a 9.4 T magnetic field, MAS frequencies of 6.2–6.8 kHz, and microwave irradiation at 264.0 GHz from a 800 mW extended interaction oscillator source, the most effective compounds are triradicals that are related to the previously-described compound DOTOPA-TEMPO (see Thurber et al., 2010), but have improved solubility in glycerol/water solvent near neutral pH. Using these compounds at 30 mM total nitroxide concentration, we observe DNP enhancement factors of 92–128 for cross-polarized 13C NMR signals from 15N,13C-labeled melittin in partially protonated glycerol/water, and build-up times of 2.6–3.8 s for 1H spin polarizations. Net sensitivity enhancements with biradical and tetraradical dopants, taking into account absolute 13C NMR signal amplitudes and build-up times, are approximately 2–4 times lower than with the best triradicals. PMID:24887201

  13. Synthesis and evaluation of nitroxide-based oligoradicals for low-temperature dynamic nuclear polarization in solid state NMR

    NASA Astrophysics Data System (ADS)

    Yau, Wai-Ming; Thurber, Kent R.; Tycko, Robert

    2014-07-01

    We describe the synthesis of new nitroxide-based biradical, triradical, and tetraradical compounds and the evaluation of their performance as paramagnetic dopants in dynamic nuclear polarization (DNP) experiments in solid state nuclear magnetic resonance (NMR) spectroscopy with magic-angle spinning (MAS). Under our experimental conditions, which include temperatures in the 25-30 K range, a 9.4 T magnetic field, MAS frequencies of 6.2-6.8 kHz, and microwave irradiation at 264.0 GHz from a 800 mW extended interaction oscillator source, the most effective compounds are triradicals that are related to the previously-described compound DOTOPA-TEMPO (see Thurber et al., 2010), but have improved solubility in glycerol/water solvent near neutral pH. Using these compounds at 30 mM total nitroxide concentration, we observe DNP enhancement factors of 92-128 for cross-polarized 13C NMR signals from 15N,13C-labeled melittin in partially protonated glycerol/water, and build-up times of 2.6-3.8 s for 1H spin polarizations. Net sensitivity enhancements with biradical and tetraradical dopants, taking into account absolute 13C NMR signal amplitudes and build-up times, are approximately 2-4 times lower than with the best triradicals.

  14. Synthesis and evaluation of nitroxide-based oligoradicals for low-temperature dynamic nuclear polarization in solid state NMR.

    PubMed

    Yau, Wai-Ming; Thurber, Kent R; Tycko, Robert

    2014-07-01

    We describe the synthesis of new nitroxide-based biradical, triradical, and tetraradical compounds and the evaluation of their performance as paramagnetic dopants in dynamic nuclear polarization (DNP) experiments in solid state nuclear magnetic resonance (NMR) spectroscopy with magic-angle spinning (MAS). Under our experimental conditions, which include temperatures in the 25-30 K range, a 9.4 T magnetic field, MAS frequencies of 6.2-6.8 kHz, and microwave irradiation at 264.0 GHz from a 800 mW extended interaction oscillator source, the most effective compounds are triradicals that are related to the previously-described compound DOTOPA-TEMPO (see Thurber et al., 2010), but have improved solubility in glycerol/water solvent near neutral pH. Using these compounds at 30 mM total nitroxide concentration, we observe DNP enhancement factors of 92-128 for cross-polarized (13)C NMR signals from (15)N,(13)C-labeled melittin in partially protonated glycerol/water, and build-up times of 2.6-3.8s for (1)H spin polarizations. Net sensitivity enhancements with biradical and tetraradical dopants, taking into account absolute (13)C NMR signal amplitudes and build-up times, are approximately 2-4 times lower than with the best triradicals. Published by Elsevier Inc.

  15. Emotional salience, emotional awareness, peculiar beliefs, and magical thinking.

    PubMed

    Berenbaum, Howard; Boden, M Tyler; Baker, John P

    2009-04-01

    Two studies with college student participants (Ns = 271 and 185) tested whether peculiar beliefs and magical thinking were associated with (a) the emotional salience of the stimuli about which individuals may have peculiar beliefs or magical thinking, (b) attention to emotion, and (c) clarity of emotion. Study 1 examined belief that a baseball team was cursed. Study 2 measured magical thinking using a procedure developed by P. Rozin and C. Nemeroff (2002). In both studies, peculiar beliefs and magical thinking were associated with Salience x Attention x Clarity interactions. Among individuals for whom the objects of the belief-magical thinking were highly emotionally salient and who had high levels of attention to emotion, higher levels of emotional clarity were associated with increased peculiar beliefs-magical thinking. In contrast, among individuals for whom the objects of the belief-magical thinking were not emotionally salient and who had high levels of attention to emotion, higher levels of emotional clarity were associated with diminished peculiar beliefs-magical thinking. (c) 2009 APA, all rights reserved.

  16. [Peter of Abano, the 'Conciliator' between magic and science].

    PubMed

    Federici Vescovini, Graziella

    2008-01-01

    Peter of Abano is a personage belonging to history as well as to legend. In this analysis his historical physiognomy of scientist and physician is reconstructed on the basis of a better knowledge of his works in medicine and astronomy (now edited), a discipline, the latest one, in which he excelled in Medieval scientific context (The Lucidator dubitabilium astronomiae (astrologiae) can be read in the critical edition by G. Federici Vescovini, Padova, Esedra, 1992). He opposed extreme position in all fields, by styling himself 'Conciliator' of opposed tendencies. He often reconfirmed a rational concept of medicine and astronomy, which dispelled any demoniac and magic features, against the fanciful legend elaborated during the following centuries.

  17. [Magical thinking in healthy people and in schizophrenia].

    PubMed

    Jarosz, M

    1996-01-01

    Different conditions of magical thinking have been analyzed. A formation of the proportion "realistic thinking - magical thinking" in paranoid schizophrenia has been discussed and the characteristic features of magical thinking in schizophrenia have been indicated.

  18. Cryogenic sample exchange NMR probe for magic angle spinning dynamic nuclear polarization

    PubMed Central

    Barnes, Alexander B.; Mak-Jurkauskas, Melody L.; Matsuki, Yoh; Bajaj, Vikram S.; van der Wel, Patrick C. A.; DeRocher, Ronald; Bryant, Jeffrey; Sirigiri, Jagadishwar R.; Temkin, Richard J.; Lugtenburg, Johan; Herzfeld, Judith; Griffin, Robert G.

    2009-01-01

    We describe a cryogenic sample exchange system that dramatically improves the efficiency of magic angle spinning (MAS) dynamic nuclear polarization (DNP) experiments by reducing the time required to change samples and by improving long-term instrument stability. Changing samples in conventional cryogenic MAS DNP/NMR experiments involves warming the probe to room temperature, detaching all cryogenic, RF, and microwave connections, removing the probe from the magnet, replacing the sample, and reversing all the previous steps, with the entire cycle requiring a few hours. The sample exchange system described here — which relies on an eject pipe attached to the front of the MAS stator and a vacuum jacketed dewar with a bellowed hole — circumvents these procedures. To demonstrate the excellent sensitivity, resolution, and stability achieved with this quadruple resonance sample exchange probe, we have performed high precision distance measurements on the active site of the membrane protein bacteriorhodopsin. We also include a spectrum of the tripeptide N-f-MLF-OH at 100 K which shows 30 Hz linewidths. PMID:19356957

  19. MagicPlate-512: A 2D silicon detector array for quality assurance of stereotactic motion adaptive radiotherapy.

    PubMed

    Petasecca, M; Newall, M K; Booth, J T; Duncan, M; Aldosari, A H; Fuduli, I; Espinoza, A A; Porumb, C S; Guatelli, S; Metcalfe, P; Colvill, E; Cammarano, D; Carolan, M; Oborn, B; Lerch, M L F; Perevertaylo, V; Keall, P J; Rosenfeld, A B

    2015-06-01

    Spatial and temporal resolutions are two of the most important features for quality assurance instrumentation of motion adaptive radiotherapy modalities. The goal of this work is to characterize the performance of the 2D high spatial resolution monolithic silicon diode array named "MagicPlate-512" for quality assurance of stereotactic body radiation therapy (SBRT) and stereotactic radiosurgery (SRS) combined with a dynamic multileaf collimator (MLC) tracking technique for motion compensation. MagicPlate-512 is used in combination with the movable platform HexaMotion and a research version of radiofrequency tracking system Calypso driving MLC tracking software. The authors reconstruct 2D dose distributions of small field square beams in three modalities: in static conditions, mimicking the temporal movement pattern of a lung tumor and tracking the moving target while the MLC compensates almost instantaneously for the tumor displacement. Use of Calypso in combination with MagicPlate-512 requires a proper radiofrequency interference shielding. Impact of the shielding on dosimetry has been simulated by (GEANT)4 and verified experimentally. Temporal and spatial resolutions of the dosimetry system allow also for accurate verification of segments of complex stereotactic radiotherapy plans with identification of the instant and location where a certain dose is delivered. This feature allows for retrospective temporal reconstruction of the delivery process and easy identification of error in the tracking or the multileaf collimator driving systems. A sliding MLC wedge combined with the lung motion pattern has been measured. The ability of the MagicPlate-512 (MP512) in 2D dose mapping in all three modes of operation was benchmarked by EBT3 film. Full width at half maximum and penumbra of the moving and stationary dose profiles measured by EBT3 film and MagicPlate-512 confirm that motion has a significant impact on the dose distribution. Motion, no motion, and motion with MLC tracking profiles agreed within 1 and 0.4 mm, respectively, for all field sizes tested. Use of electromagnetic tracking system generates a fluctuation of the detector baseline up to 10% of the full scale signal requiring a proper shielding strategy. MagicPlate-512 is also able to reconstruct the dose variation pulse-by-pulse in each pixel of the detector. An analysis of the dose transients with motion and motion with tracking shows that the tracking feedback algorithm used for this experiment can compensate effectively only the effect of the slower transient components. The fast changing components of the organ motion can contribute only to discrepancy of the order of 15% in penumbral region while the slower components can change the dose profile up to 75% of the expected dose. MagicPlate-512 is shown to be, potentially, a valid alternative to film or 2D ionizing chambers for quality assurance dosimetry in SRS or SBRT. Its high spatial and temporal resolutions allow for accurate reconstruction of the profile in any conditions with motion and with tracking of the motion. It shows excellent performance to reconstruct the dose deposition in real time or retrospectively as a function of time for detailed analysis of the effect of motion in a specific pixel or area of interest.

  20. Characterization of metabolic profile of intact non-tumor and tumor breast cells by high-resolution magic angle spinning nuclear magnetic resonance spectroscopy.

    PubMed

    Maria, Roberta M; Altei, Wanessa F; Andricopulo, Adriano D; Becceneri, Amanda B; Cominetti, Márcia R; Venâncio, Tiago; Colnago, Luiz A

    2015-11-01

    (1)H high-resolution magic angle spinning nuclear magnetic resonance ((1)H HR-MAS NMR) spectroscopy was used to analyze the metabolic profile of an intact non-tumor breast cell line (MCF-10A) and intact breast tumor cell lines (MCF-7 and MDA-MB-231). In the spectra of MCF-10A cells, six metabolites were assigned, with glucose and ethanol in higher concentrations. Fifteen metabolites were assigned in MCF-7 and MDA-MB-231 (1)H HR-MAS NMR spectra. They did not show glucose and ethanol, and the major component in both tumor cells was phosphocholine (higher in MDA-MB-231 than in MCF-7), which can be considered as a tumor biomarker of breast cancer malignant transformation. These tumor cells also show acetone signal that was higher in MDA-MB-231 cells than in MCF-7 cells. The high acetone level may be an indication of high demand for energy in MDA-MB-231 to maintain cell proliferation. The higher acetone and phosphocholine levels in MDA-MB-231 cells indicate the higher malignance of the cell line. Therefore, HR-MAS is a rapid reproducible method to study the metabolic profile of intact breast cells, with minimal sample preparation and contamination, which are critical in the analyses of slow-growth cells. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Use of high-field and low-field magnetic resonance imaging to describe the anatomy of the proximal portion of the tarsal region of nonlame horses.

    PubMed

    Biggi, Marianna; Dyson, Sue J

    2018-03-01

    OBJECTIVE To use high-field and low-field MRI to describe the anatomy of the proximal portion of the tarsal region (proximal tarsal region) of nonlame horses. SAMPLE 25 cadaveric equine tarsi. PROCEDURES The proximal portion of 1 tarsus from each of 25 nonlame horses with no history of tarsal lameness underwent high-field (1.5-T) and low-field (0.27-T) MRI. Resulting images were used to subjectively describe the anatomy of that region and obtain measurements of the collateral ligaments of the tarsocrural joint. RESULTS Long and short components of the lateral and medial collateral ligaments of the tarsocrural joint were identified. Various bundles of the short collateral ligaments were difficult to delineate on low-field images. Ligaments typically had low signal intensity in all sequences; however, multiple areas of increased signal intensity were identified at specific locations in most tarsi. This signal intensity was attributed to focal magic angle effect associated with orientation of collagen fibers within the ligaments at those locations. Subchondral bone of the distal aspect of the tibia was uniform in thickness, whereas that of the medial trochlear ridge of the talus was generally thicker than that of the lateral trochlear ridge. In most tarsi, subchondral bone of the talocalcaneal joint decreased in thickness from proximal to distal. CONCLUSIONS AND CLINICAL RELEVANCE Results generated in this study can be used as a reference for interpretation of MRI images of the proximal tarsal region in horses.

  2. Making sense of the conflicting magic numbers in WSi{sub n} clusters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abreu, Marissa Baddick; Reber, Arthur C.; Khanna, Shiv N.

    2015-08-21

    First principles studies on the geometric structure, stability, and electronic structure of WSi{sub n} clusters, n = 6-16, have been carried out to show that the observed differing “magic sizes” for WSi{sub n} clusters are associated with the nature of the growth processes. The WSi{sub 12} cluster, observed as a magic species in experiments reacting transition metal ions with silane, is not stable due to a filled shell of 18 electrons, as previously proposed, but due to its atomic structure that arrests further growth because of an endohedral transition metal site. In fact, it is found that all of thesemore » clusters, n = 6-16, have filled 5d shells except for WSi{sub 12}, which has a 5d{sup 8} configuration that is caused by crystal field splitting. The stability of WSi{sub 15}{sup +}, observed as highly stable in clusters generated by vaporizing silicon and metal carbonyls, is shown to be associated with a combination of geometric and electronic features. The findings are compared with previous results on CrSi{sub n} clusters.« less

  3. Winter Roadway Maintenance Material Enhancers (Field) Evaluation

    DOT National Transportation Integrated Search

    2018-04-06

    In this study, the performance and cost analysis of four deicers products, i.e., Aqua Salina (AS), Beet Heet (BH), Green Blast (GB), Magic Minus Zero (MMZ), and two references, Rock Salt (RS) and/or Salt Brine (SB) were evaluated through parking lot ...

  4. Aerosol Properties over the Eastern North Pacific based on Measurements from the MAGIC Field Campaign

    NASA Astrophysics Data System (ADS)

    Lewis, E. R.; Senum, G.; Springston, S. R.; Kuang, C.

    2015-12-01

    The MAGIC field campaign, funded and operated by the ARM (Atmospheric Radiation Measurement) Climate Research Facility of the US Department of Energy, occurred between September 2012 and October, 2013 aboard the Horizon Lines cargo container ship Spirit making regular trips between Los Angeles, CA and Honolulu, HI. Along this route, which lies very near the GPCI (GCSS Pacific Cross-section Intercomparison) transect, the predominant cloud regime changes from stratocumulus near the California coast to trade-wind cumulus near Hawaii. The transition between these two regimes is poorly understood and not accurately represented in models. The goal of MAGIC was to acquire statistic of this transition and thus improve its representation in models by making repeated transects through this region and measuring properties of clouds and precipitation, aerosols, radiation, and atmospheric structure. To achieve these goals, the Second ARM Mobile Facility (AMF2) was deployed on the Horizon Spirit as it ran its regular route between Los Angeles and Honolulu. AMF2 consists of three 20-foot SeaTainers and includes three radars and other instruments to measure properties of clouds and precipitation; the Aerosol Observing System (AOS), which has a suite of instruments to measure properties of aerosols; and other instruments to measure radiation, meteorological quantities, and sea surface temperature. Two technicians accompanied the AMF2, and scientists rode the ship as observers. MAGIC made nearly 20 round trips between Los Angeles and Honolulu (and thus nearly 40 excursions through the stratocumulus-to-cumulus transition) and spent 200 days at sea, collecting an unprecedented data set. Aerosol properties measured with the AOS include number concentration and size distribution, CCN activity, hygroscopic growth, and light-scattering and absorption. Additionally, more than one hundred filter samples were collected. Aerosol properties and their spatial and temporal behavior are discussed and examined in terms of other meteorological and environmental parameters.

  5. Pulsed field gradient magic angle spinning NMR self-diffusion measurements in liquids

    NASA Astrophysics Data System (ADS)

    Viel, Stéphane; Ziarelli, Fabio; Pagès, Guilhem; Carrara, Caroline; Caldarelli, Stefano

    2008-01-01

    Several investigations have recently reported the combined use of pulsed field gradient (PFG) with magic angle spinning (MAS) for the analysis of molecular mobility in heterogeneous materials. In contrast, little attention has been devoted so far to delimiting the role of the extra force field induced by sample rotation on the significance and reliability of self-diffusivity measurements. The main purpose of this work is to examine this phenomenon by focusing on pure liquids for which its impact is expected to be largest. Specifically, we show that self-diffusion coefficients can be accurately determined by PFG MAS NMR diffusion measurements in liquids, provided that specific experimental conditions are met. First, the methodology to estimate the gradient uniformity and to properly calibrate its absolute strength is briefly reviewed and applied on a MAS probe equipped with a gradient coil aligned along the rotor spinning axis, the so-called 'magic angle gradient' coil. Second, the influence of MAS on the outcome of PFG MAS diffusion measurements in liquids is investigated for two distinct typical rotors of different active volumes, 12 and 50 μL. While the latter rotor led to totally unreliable results, especially for low viscosity compounds, the former allowed for the determination of accurate self-diffusion coefficients both for fast and slowly diffusing species. Potential implications of this work are the possibility to measure accurate self-diffusion coefficients of sample-limited mixtures or to avoid radiation damping interferences in NMR diffusion measurements. Overall, the outlined methodology should be of interest to anyone who strives to improve the reliability of MAS diffusion studies, both in homogeneous and heterogeneous media.

  6. Magic 2010 RASR Team

    DTIC Science & Technology

    2010-12-15

    MAGIC 2010 – FINAL REPORT RASR TEAM - CONTRACT NO: FA2386-10-1-4021 December 15, 2010 Final Report for AOARD Grant FA23861014021 – MAGIC ... MAGIC 2010 Competition - Robotic Research Team (RASR) Abstract: The RASR team developed a system for the coordination of groups of unmanned...accomplish those missions. Our team goal was to develop a system that can provide long term value to the war-fighter, utilizing MAGIC 2010 as a stepping

  7. WE-E-18A-07: MAGIC: Multi-Acquisition Gain Image Correction for Mobile X-Ray Systems with Intrinsic Localization Crosshairs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Park, Y; Sharp, G

    2014-06-15

    Purpose: Gain calibration for X-ray imaging systems with movable flat panel detectors (FPD) and intrinsic crosshairs is a challenge due to the geometry dependence of the heel effect and crosshair artifact. This study aims to develop a gain correction method for such systems by implementing the multi-acquisition gain image correction (MAGIC) technique. Methods: Raw flat-field images containing crosshair shadows and heel effect were acquired in 4 different FPD positions with fixed exposure parameters. The crosshair region was automatically detected and substituted with interpolated values from nearby exposed regions, generating a conventional single-image gain-map for each FPD position. Large kernel-based correctionmore » was applied to these images to correct the heel effect. A mask filter was used to invalidate the original cross-hair regions previously filled with the interpolated values. A final, seamless gain-map was created from the processed images by either the sequential filling (SF) or selective averaging (SA) techniques developed in this study. Quantitative evaluation was performed based on detective quantum efficiency improvement factor (DQEIF) for gain-corrected images using the conventional and proposed techniques. Results: Qualitatively, the MAGIC technique was found to be more effective in eliminating crosshair artifacts compared to the conventional single-image method. The mean DQEIF over the range of frequencies from 0.5 to 3.5 mm-1 were 1.09±0.06, 2.46±0.32, and 3.34±0.36 in the crosshair-artifact region and 2.35±0.31, 2.33±0.31, and 3.09±0.34 in the normal region, for the conventional, MAGIC-SF, and MAGIC-SA techniques, respectively. Conclusion: The introduced MAGIC technique is appropriate for gain calibration of an imaging system associated with a moving FPD and an intrinsic crosshair. The technique showed advantages over a conventional single image-based technique by successfully reducing residual crosshair artifacts, and higher image quality with respect to DQE.« less

  8. Magic with Magic Squares.

    ERIC Educational Resources Information Center

    Wills, Herbert III

    1989-01-01

    Describes ways to make magic squares of 4 by 4 matrices. Presents two handouts: (1) Sets of 4 Numbers from 1 to 16 Whose Sum is 34; and (2) The Durer Square. Shows patterns which appeared in the magic squares, such as squares, chevrons, rhomboids, and trapezoids. (YP)

  9. The Illusory Beliefs Inventory: a new measure of magical thinking and its relationship with obsessive compulsive disorder.

    PubMed

    Kingdon, Bianca L; Egan, Sarah J; Rees, Clare S

    2012-01-01

    Magical thinking has been proposed to have an aetiological role in obsessive compulsive disorder (OCD). To address the limitations of existing measures of magical thinking we developed and validated a new 24-item measure of magical thinking, the Illusory Beliefs Inventory (IBI). The validation sample comprised a total of 1194 individuals across two samples recruited via an Internet based survey. Factor analysis identified three subscales representing domains relevant to the construct of magical thinking: Magical Beliefs, Spirituality, and Internal State and Thought Action Fusion. The scale had excellent internal consistency and evidence of convergent and discriminant validity. Evidence of criterion-related concurrent validity confirmed that magical thinking is a cognitive domain associated with OCD and is largely relevant to neutralizing, obsessing and hoarding symptoms. It is important for future studies to extend the evidence of the psychometric properties of the IBI in new populations and to conduct longitudinal studies to examine the aetiological role of magical thinking.

  10. Manufacturing Magic and Computational Creativity

    PubMed Central

    Williams, Howard; McOwan, Peter W.

    2016-01-01

    This paper describes techniques in computational creativity, blending mathematical modeling and psychological insight, to generate new magic tricks. The details of an explicit computational framework capable of creating new magic tricks are summarized, and evaluated against a range of contemporary theories about what constitutes a creative system. To allow further development of the proposed system we situate this approach to the generation of magic in the wider context of other areas of application in computational creativity in performance arts. We show how approaches in these domains could be incorporated to enhance future magic generation systems, and critically review possible future applications of such magic generating computers. PMID:27375533

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Petasecca, M., E-mail: marcop@uow.edu.au; Newall, M. K.; Aldosari, A. H.

    Purpose: Spatial and temporal resolutions are two of the most important features for quality assurance instrumentation of motion adaptive radiotherapy modalities. The goal of this work is to characterize the performance of the 2D high spatial resolution monolithic silicon diode array named “MagicPlate-512” for quality assurance of stereotactic body radiation therapy (SBRT) and stereotactic radiosurgery (SRS) combined with a dynamic multileaf collimator (MLC) tracking technique for motion compensation. Methods: MagicPlate-512 is used in combination with the movable platform HexaMotion and a research version of radiofrequency tracking system Calypso driving MLC tracking software. The authors reconstruct 2D dose distributions of smallmore » field square beams in three modalities: in static conditions, mimicking the temporal movement pattern of a lung tumor and tracking the moving target while the MLC compensates almost instantaneously for the tumor displacement. Use of Calypso in combination with MagicPlate-512 requires a proper radiofrequency interference shielding. Impact of the shielding on dosimetry has been simulated by GEANT4 and verified experimentally. Temporal and spatial resolutions of the dosimetry system allow also for accurate verification of segments of complex stereotactic radiotherapy plans with identification of the instant and location where a certain dose is delivered. This feature allows for retrospective temporal reconstruction of the delivery process and easy identification of error in the tracking or the multileaf collimator driving systems. A sliding MLC wedge combined with the lung motion pattern has been measured. The ability of the MagicPlate-512 (MP512) in 2D dose mapping in all three modes of operation was benchmarked by EBT3 film. Results: Full width at half maximum and penumbra of the moving and stationary dose profiles measured by EBT3 film and MagicPlate-512 confirm that motion has a significant impact on the dose distribution. Motion, no motion, and motion with MLC tracking profiles agreed within 1 and 0.4 mm, respectively, for all field sizes tested. Use of electromagnetic tracking system generates a fluctuation of the detector baseline up to 10% of the full scale signal requiring a proper shielding strategy. MagicPlate-512 is also able to reconstruct the dose variation pulse-by-pulse in each pixel of the detector. An analysis of the dose transients with motion and motion with tracking shows that the tracking feedback algorithm used for this experiment can compensate effectively only the effect of the slower transient components. The fast changing components of the organ motion can contribute only to discrepancy of the order of 15% in penumbral region while the slower components can change the dose profile up to 75% of the expected dose. Conclusions: MagicPlate-512 is shown to be, potentially, a valid alternative to film or 2D ionizing chambers for quality assurance dosimetry in SRS or SBRT. Its high spatial and temporal resolutions allow for accurate reconstruction of the profile in any conditions with motion and with tracking of the motion. It shows excellent performance to reconstruct the dose deposition in real time or retrospectively as a function of time for detailed analysis of the effect of motion in a specific pixel or area of interest.« less

  12. High Resolution Magic Angle Spinning Nuclear Magnetic Resonance (HRMAS NMR) for Studies of Reactive Fabrics

    DTIC Science & Technology

    2015-11-01

    Group Chemistry, 2010, 9, 205-219. 6 C. A. S. Brevett and K. B. Sumpter, “ Sulfur Mustard Degradation on Ambient and Moist Concrete ”, ECBC Technical...reactions of reagents including chemical weapons on materials like concrete , soil, and sand, as well as reactive polymers.3,4,5,6,7 There are...Sumpter, G. W. Wagner, “Degradation of Mustard on Concrete : GC/MSD and SSMAS,” ECBC Technical Report ECBC-TR-482, Edgewood Chemical Biological Center

  13. Controlling coherence using the internal structure of hard pi pulses.

    PubMed

    Dong, Yanqun; Ramos, R G; Li, Dale; Barrett, S E

    2008-06-20

    The tiny difference between hard pi pulses and their delta-function approximation can be exploited to control coherence. Variants on the magic echo that work despite a large spread in resonance offsets are demonstrated using the zeroth- and first-order average Hamiltonian terms, for 13C NMR in 60C. The 29Si NMR linewidth of silicon has been reduced by a factor of about 70,00 using this approach, which also has potential applications in magnetic resonance microscopy and imaging of solids.

  14. From MAGIC to CTA: the INAF participation to Cherenkov Telescopes experiments for very high energy astrophysics .

    NASA Astrophysics Data System (ADS)

    Antonelli, L. A.; INAF MAGIC Collaboration

    The next decade can be considered the "golden age" of the Gamma Ray Astronomy with the two satellites for Gamma Ray Astronomy (AGILE and GLAST) in orbit. Therefore, thanks to many other X-ray experiments already in orbit (e.g. Swift, Chandra, NewtonXMM, etc.) it will be possible to image the Universe for the first time all over the electromagnetic spectrum almost contemporarily. The new generations of ground-based very high gamma-ray instruments are ready to extend the observed band also to the very high frequencies. Scientists from the Italian National Institute for Astrophysics (INAF) are involved in many, both space- and ground- based gamma ray experiments, and recently such an involvement has been largely improved in the field of the Imaging Atmospheric Cherenkov Telescopes (IACT). INAF is now member of the MAGIC collaboration and is participating to the realization of the second MAGIC telescope. MAGIC, as well other IACT experiments, is not operated as an observatory so a proper guest observer program does not exist. A consortium of European scientists (including INAF scientists) is thus now thinking to the design of a new research infrastructure: the Cherenkov Telescope Array (CTA). CTA is conceived to provide 10 times the sensitivity of current instruments, combined with increased flexibility and increased coverage from some 10 GeV to some 100 TeV. CTA will be operated as an observatory to serve a wider community of astronomer and astroparticle physicists.

  15. Watching films with magical content facilitates creativity in children.

    PubMed

    Subbotsky, Eugene; Hysted, Claire; Jones, Nicola

    2010-08-01

    Two experiments examined the possible link between magical thinking and creativity in preschool children. In Exp. 1, 4- and 6-yr.-old children were shown a film with either a magical or nonmagical theme. Results indicated that the mean scores of children shown the magical film was significantly higher than that of children watching the nonmagical film on the majority of subsequent creativity tests for both age groups. This trend was also found for 6-yr.-olds' drawings of impossible items. In Exp. 2, Exp. 1 was replicated successfully with 6- and 8-yr.-old children. Exposing children to a film with a magical theme did not affect their beliefs about magic. The results were interpreted to accentuate the role of magical thinking in children's cognitive development. Classroom implications of the results were also discussed.

  16. Polar and singular value decomposition of 3×3 magic squares

    NASA Astrophysics Data System (ADS)

    Trenkler, Götz; Schmidt, Karsten; Trenkler, Dietrich

    2013-07-01

    In this note, we find polar as well as singular value decompositions of a 3×3 magic square, i.e. a 3×3 matrix M with real elements where each row, column and diagonal adds up to the magic sum s of the magic square.

  17. Dynamic Nuclear Polarization and other magnetic ideas at EPFL.

    PubMed

    Bornet, Aurélien; Milani, Jonas; Wang, Shutao; Mammoli, Daniele; Buratto, Roberto; Salvi, Nicola; Segaw, Takuya F; Vitzthum, Veronika; Miéville, Pascal; Chinthalapalli, Srinivas; Perez-Linde, Angel J; Carnevale, Diego; Jannin, Sami; Caporinia, Marc; Ulzega, Simone; Rey, Martial; Bodenhausen, Geoffrey

    2012-01-01

    Although nuclear magnetic resonance (NMR) can provide a wealth of information, it often suffers from a lack of sensitivity. Dynamic Nuclear Polarization (DNP) provides a way to increase the polarization and hence the signal intensities in NMR spectra by transferring the favourable electron spin polarization of paramagnetic centres to the surrounding nuclear spins through appropriate microwave irradiation. In our group at EPFL, two complementary DNP techniques are under investigation: the combination of DNP with magic angle spinning at temperatures near 100 K ('MAS-DNP'), and the combination of DNP at 1.2 K with rapid heating followed by the transfer of the sample to a high-resolution magnet ('dissolution DNP'). Recent applications of MAS-DNP to surfaces, as well as new developments of magnetization transfer of (1)H to (13)C at 1.2 K prior to dissolution will illustrate the work performed in our group. A second part of the paper will give an overview of some 'non-enhanced' activities of our laboratory in liquid- and solid-state NMR.

  18. The MAGIC (Manually Assisted Gaming of Integrated Combat) Model,

    DTIC Science & Technology

    1982-05-01

    IP -6 7 6 7 Zo - A O - ?G O 6 7 9 N L mhhhhh1h8I 1-I THE MAGIC (MANUALLY ASSISTED GAMING OF INTEGRATED COMBAT) MODEL Milton G. Weiner May 1982 L io...Corporation Santa Monica, California 90406 - - ~-. - - -i 77 THE MAGIC (MANUALLY ASSISTED GAMING OF INTEGRATED COMBAT) MODEL Milton G. Weiner May 1982 THE... MAGIC (MANUALLY ASSISTED GAMING OF INTEGRATED COMBAT) MODEL Milton G. Weiner The Rand Corporation, Santa Monica, California The MAGIC model isn’Vt

  19. A LOW-E MAGIC ANGLE SPINNING PROBE FOR BIOLOGICAL SOLID STATE NMR AT 750 MHz

    PubMed Central

    McNeill, Seth A.; Gor’kov, Peter L.; Shetty, Kiran; Brey, William W.; Long, Joanna R.

    2009-01-01

    Crossed-coil NMR probes are a useful tool for reducing sample heating for biological solid state NMR. In a crossed-coil probe, the higher frequency 1H field, which is the primary source of sample heating in conventional probes, is produced by a separate low-inductance resonator. Because a smaller driving voltage is required, the electric field across the sample and the resultant heating is reduced. In this work we describe the development of a magic angle spinning (MAS) solid state NMR probe utilizing a dual resonator. This dual resonator approach, referred to as “Low-E,” was originally developed to reduce heating in samples of mechanically aligned membranes. The study of inherently dilute systems, such as proteins in lipid bilayers, via MAS techniques requires large sample volumes at high field to obtain spectra with adequate signal-to-noise ratio under physiologically relevant conditions. With the Low-E approach, we are able to obtain homogeneous and sufficiently strong radiofrequency fields for both 1H and 13C frequencies in a 4 mm probe with a 1H frequency of 750 MHz. The performance of the probe using windowless dipolar recoupling sequences is demonstrated on model compounds as well as membrane embedded peptides. PMID:19138870

  20. Magical ideation is related to questionnaire but not behavioural measures of handedness.

    PubMed

    Grimshaw, Gina M; Yelle, Serena K; Schoger, Jamie; Bright, Kathleen S

    2008-01-01

    Magical ideation has repeatedly been shown to be related to handedness, with mixed-handers exhibiting higher levels of magical thinking. However, most previous research has assessed hand preference with a questionnaire measure, leaving open the possibility that the correlation reflects some aspect of questionnaire-taking behaviour and not an underlying neuropsychological relationship. The present study addressed this issue by administering the Magical Ideation Scale (Eckblad & Chapman, 1983), the Waterloo Handedness Questionnaire-Revised (Elias, Bryden, & Bulman-Fleming, 1998), and a manual dot-filling task (Tapley & Bryden, 1985) as a behavioural measure of handedness to an undergraduate student sample. The expected relationship between magical ideation and handedness as assessed by the questionnaire was observed. However, magical ideation was not related to the behavioural measure of handedness. Results cast doubt on a neuropsychological interpretation of the relationship between handedness and magical ideation in sub-clinical populations.

  1. On Super Edge-magic Total Labeling of Modified Watermill Graph

    NASA Astrophysics Data System (ADS)

    Nurdin; Ungko, T. S.; Gormantara, J.; Abdullah, A.; Aulyah, S.; Nikita

    2018-03-01

    An edge-magic total labeling on a graph G is one-to-one map from V(G) ∪ E(G) onto the set of integers 1,2, ...,ν + e, where ν = |V(G)| and e = |E(G)|, with the property that, given any edge uv, f(u) + f(u, ν}) + f(ν) = k for every u,v ∈ V(G), and k is called magic valuation. An edge-magic total labeling f is called super edge-magic total if f(v(G)) = {1,2 ...,|V(G)|} and f(E(G)) = {|V(G)| + 1, |V(G)| + 2,... |V(G) + E(G)|}. In this paper we investigate edge-magic total labeling of a new graph called modified Watermill graph. Furthermore, the magic valuation of the modified Watermill graph WM(n) is k=\\frac{1}{2}(21n+3), for n odd, n ≥ 3.

  2. 78 FR 7464 - Large Scale Networking (LSN)-Middleware And Grid Interagency Coordination (MAGIC) Team

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-01

    ... Coordination (MAGIC) Team AGENCY: The Networking and Information Technology Research and Development (NITRD... (703) 292-4873. Date/Location: The MAGIC Team meetings are held on the first Wednesday of each month, 2... basis. WebEx participation is available for each meeting. Please reference the MAGIC Team Web site for...

  3. Z3 -vertex magic total labeling and Z3 -edge magic total labelingfor the extended duplicate graph of quadrilateral snake

    NASA Astrophysics Data System (ADS)

    Indira, P.; Selvam, B.; Thirusangu, K.

    2018-04-01

    Based on the works of Kotzig, Rosa and MacDougall et.al., we present algorithms and prove the existence of Z3-vertex magic total labeling and Z3-edge magic total labeling for the extended duplicate graph of quadrilateral snake.

  4. Relationships between magical thinking, obsessive-compulsiveness and other forms of anxiety in a sample of non-clinical children.

    PubMed

    Simonds, Laura M; Demetre, James D; Read, Cristina

    2009-06-01

    Despite the obvious phenomenological similarities between magical thinking and obsessive-compulsiveness, the relationship between them has been the subject of few empirical investigations in samples of children. The present study aimed to examine the relationship between a general epistemic stance towards magical causation and tendencies towards obsessive-compulsiveness in a non-clinical sample of schoolchildren. One-hundred and two children, aged between 5 and 10 years (48 boys and 54 girls), completed questionnaire measures designed to assess magical thinking, obsessive-compulsiveness, and other forms of anxiety. School teachers completed a measure of strengths and difficulties for each child. General belief in magical causation was correlated with all types of anxiety, not just obsessive-compulsiveness, with significant correlations shown for boys in the sample, but not girls. General belief in magical causation contributed little to the prediction of obsessive-compulsiveness beyond general anxiety. In this study, a general epistemic stance towards magical causation did not differentiate obsessive-compulsiveness from other anxiety dimensions. The findings are considered in the context of developmental theories of magical and scientific causal reasoning.

  5. Affirming the Artist Practitioner Researcher

    ERIC Educational Resources Information Center

    Kiili, Rebecca Kapolei

    2017-01-01

    The author's introduction to the field of qualitative research in the EdD program began with analyzing the artistry of a practitioner researcher. Arriving in the space of an emerging artist practitioner researcher has been soulfully synchronistic and life affirming because of the magic the author has experienced in the convergence and alignment of…

  6. The Grammar of Fantasy.

    ERIC Educational Resources Information Center

    Rodari, Gianni

    1998-01-01

    Depicts how any word chosen by chance can function as a magical word to exhume fields of memory and excite imagination. Details several word games of invention for children (such as the "fantastic binomial," using creative errors, and "Little Red Riding Hood in a Helicopter") that juxtapose normally unrelated words and that can…

  7. Pure and Poetic: Butterfly in the Quantum World

    NASA Astrophysics Data System (ADS)

    Satija, Indubala

    Story of the Hofstadter butterfly is a magical occurrence in a quantum flatland of two-dimensional crystals in a magnetic field. In this drama, the magnetic flux plays the role of Planck constant, linking the variables x and p in the butterfly Hamiltonian H = cosx + cosp as [ x , p ] = iℏ . It is a story of reunion of Descartes and Pythagoras and tale of this quantum fractal is related to Integral Apollonian gaskets. Integers rule the butterfly landscape as quantum numbers of Hall conductivity while irrational numbers emerge as the asymptotic magnification of these topological integers in the kaleidoscopic images of the butterfly. Simple variations of the above Hamiltonian generates a wide spectrum of physical phenomenon. For example, the Hamiltonian H = cosx + λcosp with the parameter λ ≠ 1 in its zero energy solution hides the critical point of a topological transition in a superconducting chain and thus barely misses the Majorana fermions. Another example is the Hamiltonian obtained by including terms like cos (x +/- p) which for flux half exhibits Dirac semi-metallic states in addition to all integer quantum Hall states corresponding to all possible solutions of the Diophantine equation for this value of the magnetic flux. In this analytically tractable model where the parameter λ varies periodically with time, the topological states are described by edge modes whose dispersion is given by a pure cosine function. Finally, nature has composed beautiful variations of the Hofstadter butterfly not only in systems such as Penrose and Kagame lattices and also in the relativistic colorful world of quarks and antiquarks.

  8. The Magic of Magic: The Effect of Magic Tricks on Subsequent Engagement with Lecture Material

    ERIC Educational Resources Information Center

    Moss, Simon A.; Irons, Melanie; Boland, Martin

    2017-01-01

    Background and aims: Lecturers often present entertaining videos, or organize a variety of amusing demonstrations, to foster student engagement or to encourage critical analysis. Magic tricks, in particular, have been shown to activate neural circuits that underpin motivation or problem-solving and, therefore, could be beneficial during lectures.…

  9. Characterization of completely k-magic regular graphs

    NASA Astrophysics Data System (ADS)

    Eniego, A. A.; Garces, I. J. L.

    2017-10-01

    Let k ∈ ℕ and c ∈ ℤ k . A graph G is said to be c-sum k-magic if there is a labeling ℓ : E(G) → ℤ k {0} such that Σ u∈N(v) ℓ(uv) ≡ c (mod k) for every vertex v of G, where N(v) is the neighborhood of v in G. We say that G is completely k-magic whenever it is c-sum k-magic for every c ∈ ℤ k . In this paper, we characterize all completely k-magic regular graphs.

  10. MAGIC upper limits on the GRB 090102 afterglow

    DOE PAGES

    Aleksic, J.; Ansoldi, S.; Antonelli, L. A.; ...

    2013-12-09

    Indications of a GeV component in the emission from gamma-ray bursts (GRBs) are known since the Energetic Gamma-Ray Experiment Telescope observations during the 1990s and they have been confirmed by the data of the Fermi satellite. Our results have, however, shown that our understanding of GRB physics is still unsatisfactory. The new generation of Cherenkov observatories and in particular the MAGIC telescope, allow for the first time the possibility to extend the measurement of GRBs from several tens up to hundreds of GeV energy range. Both leptonic and hadronic processes have been suggested to explain the possible GeV/TeV counterpart ofmore » GRBs. Observations with ground-based telescopes of very high energy (VHE) photons (E > 30 GeV) from these sources are going to play a key role in discriminating among the different proposed emission mechanisms, which are barely distinguishable at lower energies. MAGIC telescope observations of the GRB 090102 (z = 1.547) field and Fermi Large Area Telescope data in the same time interval are analysed to derive upper limits of the GeV/TeV emission. We compare these results to the expected emissions evaluated for different processes in the framework of a relativistic blastwave model for the afterglow. Simultaneous upper limits with Fermi and a Cherenkov telescope have been derived for this GRB observation. We obtained results compatible with the expected emission although the difficulties in predicting the HE and VHE emission for the afterglow of this event makes it difficult to draw firmer conclusions. Nonetheless, MAGIC sensitivity in the energy range of overlap with space-based instruments (above about 40 GeV) is about one order of magnitude better with respect to Fermi. This makes evident the constraining power of ground-based observations and shows that the MAGIC telescope has reached the required performance to make possible GRB multiwavelength studies in the VHE range.« less

  11. Grade classification of neuroepithelial tumors using high-resolution magic-angle spinning proton nuclear magnetic resonance spectroscopy and pattern recognition.

    PubMed

    Chen, WenXue; Lou, HaiYan; Zhang, HongPing; Nie, Xiu; Lan, WenXian; Yang, YongXia; Xiang, Yun; Qi, JianPin; Lei, Hao; Tang, HuiRu; Chen, FenEr; Deng, Feng

    2011-07-01

    Clinical data have shown that survival rates vary considerably among brain tumor patients, according to the type and grade of the tumor. Metabolite profiles of intact tumor tissues measured with high-resolution magic-angle spinning proton nuclear magnetic resonance spectroscopy (HRMAS (1)H NMRS) can provide important information on tumor biology and metabolism. These metabolic fingerprints can then be used for tumor classification and grading, with great potential value for tumor diagnosis. We studied the metabolic characteristics of 30 neuroepithelial tumor biopsies, including two astrocytomas (grade I), 12 astrocytomas (grade II), eight anaplastic astrocytomas (grade III), three glioblastomas (grade IV) and five medulloblastomas (grade IV) from 30 patients using HRMAS (1)H NMRS. The results were correlated with pathological features using multivariate data analysis, including principal component analysis (PCA). There were significant differences in the levels of N-acetyl-aspartate (NAA), creatine, myo-inositol, glycine and lactate between tumors of different grades (P<0.05). There were also significant differences in the ratios of NAA/creatine, lactate/creatine, myo-inositol/creatine, glycine/creatine, scyllo-inositol/creatine and alanine/creatine (P<0.05). A soft independent modeling of class analogy model produced a predictive accuracy of 87% for high-grade (grade III-IV) brain tumors with a sensitivity of 87% and a specificity of 93%. HRMAS (1)H NMR spectroscopy in conjunction with pattern recognition thus provides a potentially useful tool for the rapid and accurate classification of human brain tumor grades.

  12. A robust heteronuclear dipolar recoupling method comparable to TEDOR for proteins in magic-angle spinning solid-state NMR

    NASA Astrophysics Data System (ADS)

    Zhang, Zhengfeng; Li, Jianping; Chen, Yanke; Xie, Huayong; Yang, Jun

    2017-12-01

    In this letter, we propose a robust heteronuclear dipolar recoupling method for proteins in magic-angle spinning (MAS) solid-state NMR. This method is as simple, robust and efficient as the well-known TEDOR in the aspect of magnetization transfer between 15N and 13C. Deriving from our recent band-selective dual back-to-back pulses (DBP) (Zhang et al., 2016), this method uses new phase-cycling schemes to realize broadband DBP (Bro-DBP). For broadband 15N-13C magnetization transfer (simultaneous 15N → 13C‧ and 15N → 13Cα), Bro-DBP has almost the same 15N → 13Cα efficiency while offers 30-40% enhancement on 15N → 13C‧ transfer, compared to TEDOR. Besides, Bro-DBP can also be used as a carbonyl (13C‧)-selected method, whose 15N → 13C‧ efficiency is up to 1.7 times that of TEDOR and is also higher than that of band-selective DBP. The performance of Bro-DBP is demonstrated on the N-formyl-[U-13C,15N]-Met-Leu-Phe-OH (fMLF) peptide and the U-13C, 15N labeled β1 immunoglobulin binding domain of protein G (GB1) microcrystalline protein. Since Bro-DBP is as robust, simple and efficient as TEDOR, we believe it is very useful for protein studies in MAS solid-state NMR.

  13. Frequency-agile gyrotron for electron decoupling and pulsed dynamic nuclear polarization

    NASA Astrophysics Data System (ADS)

    Scott, Faith J.; Saliba, Edward P.; Albert, Brice J.; Alaniva, Nicholas; Sesti, Erika L.; Gao, Chukun; Golota, Natalie C.; Choi, Eric J.; Jagtap, Anil P.; Wittmann, Johannes J.; Eckardt, Michael; Harneit, Wolfgang; Corzilius, Björn; Th. Sigurdsson, Snorri; Barnes, Alexander B.

    2018-04-01

    We describe a frequency-agile gyrotron which can generate frequency-chirped microwave pulses. An arbitrary waveform generator (AWG) within the NMR spectrometer controls the microwave frequency, enabling synchronized pulsed control of both electron and nuclear spins. We demonstrate that the acceleration of emitted electrons, and thus the microwave frequency, can be quickly changed by varying the anode voltage. This strategy results in much faster frequency response than can be achieved by changing the potential of the electron emitter, and does not require a custom triode electron gun. The gyrotron frequency can be swept with a rate of 20 MHz/μs over a 670 MHz bandwidth in a static magnetic field. We have already implemented time-domain electron decoupling with dynamic nuclear polarization (DNP) magic angle spinning (MAS) with this device. In this contribution, we show frequency-swept DNP enhancement profiles recorded without changing the NMR magnet or probe. The profile of endofullerenes exhibits a DNP profile with a <10 MHz linewidth, indicating that the device also has sufficient frequency stability, and therefore phase stability, to implement pulsed DNP mechanisms such as the frequency-swept solid effect. We describe schematics of the mechanical and vacuum construction of the device which includes a novel flanged sapphire window assembly. Finally, we discuss how commercially available continuous-wave gyrotrons can potentially be converted into similar frequency-agile high-power microwave sources.

  14. Radiofrequency fields in MAS solid state NMR probes

    NASA Astrophysics Data System (ADS)

    Tošner, Zdeněk; Purea, Armin; Struppe, Jochem O.; Wegner, Sebastian; Engelke, Frank; Glaser, Steffen J.; Reif, Bernd

    2017-11-01

    We present a detailed analysis of the radiofrequency (RF) field over full volume of a rotor that is generated in a solenoid coil. On top of the usually considered static distribution of amplitudes along the coil axis we describe dynamic radial RF inhomogeneities induced by sample rotation. During magic angle spinning (MAS), the mechanical rotation of the sample about the magic angle, a spin packet travels through areas of different RF fields and experiences periodical modulations of both the RF amplitude and the phase. These modulations become particularly severe at the end regions of the coil where the relative RF amplitude varies up to ±25% and the RF phase changes within ±30°. Using extensive numerical simulations we demonstrate effects of RF inhomogeneity on pulse calibration and for the ramped CP experiment performed at a wide range of MAS rates. In addition, we review various methods to map RF fields using a B0 gradient along the sample (rotor axis) for imaging purposes. Under such a gradient, a nutation experiment provides directly the RF amplitude distribution, a cross polarization experiment images the correlation of the RF fields on the two channels according to the Hartmann-Hahn matching condition, while a spin-lock experiment allows to calibrate the RF amplitude employing the rotary resonance recoupling condition. Knowledge of the RF field distribution in a coil provides key to understand its effects on performance of a pulse sequence at the spectrometer and enables to set robustness requirements in the experimental design.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shlapakovski, A. S.; Beilin, L.; Krasik, Ya. E.

    Nanosecond-scale evolution of plasma and RF electromagnetic fields during the release of energy from a microwave pulse compressor with a plasma interference switch was investigated numerically using the code MAGIC. The plasma was simulated in the scope of the gas conductivity model in MAGIC. The compressor embodied an S-band cavity and H-plane waveguide tee with a shorted side arm filled with pressurized gas. In a simplified approach, the gas discharge was initiated by setting an external ionization rate in a layer crossing the side arm waveguide in the location of the electric field antinode. It was found that with increasingmore » ionization rate, the microwave energy absorbed by the plasma in the first few nanoseconds increases, but the absorption for the whole duration of energy release, on the contrary, decreases. In a hybrid approach modeling laser ignition of the discharge, seed electrons were set around the electric field antinode. In this case, the plasma extends along the field forming a filament and the plasma density increases up to the level at which the electric field within the plasma decreases due to the skin effect. Then, the avalanche rate decreases but the density still rises until the microwave energy release begins and the electric field becomes insufficient to support the avalanche process. The extraction of the microwave pulse limits its own power by terminating the rise of the plasma density and filament length. For efficient extraction, a sufficiently long filament of dense plasma must have sufficient time to be formed.« less

  16. Pair Creation Transparency in Gamma-Ray Pulsars

    NASA Astrophysics Data System (ADS)

    Story, Sarah A.

    Pulsars are rapidly rotating, highly magnetized neutron stars that produce photon pulses in energies from radio to gamma-rays. The population of known gamma-ray pulsars has been increased nearly twenty-fold in the past six years since the launch of the Fermi Gamma-Ray Space Telescope; it now exceeds 145 sources and has defined an important part of Fermi's science legacy. In order to understand the detectability of pulsars in gamma-rays, it is important to consider not only the radiative mechanisms that produce gamma-rays, but the processes that can attenuate photons before they can leave the pulsar magnetosphere. Here I explore two such processes, one-photon magnetic pair creation and two-photon pair creation. Magnetic pair creation has been at the core of radio pulsar paradigms and central to polar cap models of gamma-ray pulsars for over three decades. Among the population characteristics well established for Fermi pulsars is the common occurrence of exponential turnovers in the spectra in the 1-10 GeV range. These turnovers are too gradual to arise from magnetic pair creation in the strong magnetic fields of pulsar inner magnetospheres. By demanding insignificant photon attenuation precipitated by such single-photon pair creation, the energies of these turnovers for Fermi pulsars can be used to compute lower bounds for the typical altitude of GeV band emission. In this thesis, I explore such pair transparency constraints below the turnover energy and update earlier altitude bound determinations that have been deployed in various gamma-ray pulsar papers by the Fermi-LAT collaboration. For low altitude emission locales, general relativistic influences are found to be important, increasing cumulative opacity, shortening the photon attenuation lengths, and also reducing the maximum energy that permits escape of photons from a neutron star magnetosphere. Rotational aberration influences are also explored, and are found to be small at low altitudes, except near the magnetic pole. Our analysis clearly demonstrates that including near-threshold physics in the pair creation rate is essential to deriving accurate attenuation lengths and escape energies. The altitude bounds we compute for Fermi pulsars are typically in the range of 2-7 stellar radii and provide key information on the emission altitude in radio quiet pulsars that do not possess double peaked pulse profiles. The bound for the Crab pulsar is at a much higher altitude, with the detection by the atmospheric Cherenkov telescope MAGIC out to 350-400 GeV implying a lower bound of 310 km to the emission region, i.e., approximately 20% of the light cylinder radius. These results are also extended to the super-critical field domain, where it is found that emission in magnetars originating below around 10 stellar radii will not appear in the Fermi-LAT band. Two-photon pair creation becomes important at high altitudes and for photons produced by curvature radiation from charges flowing downward along magnetic field lines. Because the efficiency of two-photon pair creation does not depend on the local magnetic field strength, it can continue to be active in the weak-field regions far from the neutron star. It is found that two-photon pair creation can strongly attenuate photons emitted from downward-traveling charges except at very high altitudes of emission, but in the absence of rotational aberration, it is unable to produce significant opacity for upward-traveling charges unless unrealistically high neutron star surface temperatures are assumed.

  17. Sleightly Persuasive: Using Magic To Teach Principles of Persuasion.

    ERIC Educational Resources Information Center

    Frasier, C. Jay

    Magic can be used in the communication classroom as a means for introducing and/or illustrating the subject of persuasion. A magical effect which fools the class can lead to an early discussion of the need to be a critical consumer of persuasive messages. Magic can also be used to introduce the subject of ethics in persuasion. Each student can be…

  18. Magical Ideation, Creativity, Handedness, and Cerebral Asymmetries: A Combined Behavioural and fMRI Study

    ERIC Educational Resources Information Center

    Badzakova-Trajkov, Gjurgjica; Haberling, Isabelle S.; Corballis, Michael C.

    2011-01-01

    Magical ideation has been shown to be related to measures of hand preference, in which those with mixed handedness exhibit higher levels of magical ideation than those with either consistent left- or right-handedness. It is unclear whether the relation between magical ideation and hand preference is the result of a bias in questionnaire-taking…

  19. Compact Magic-T using microstrip-slotline transitions

    NASA Technical Reports Server (NTRS)

    U-Yen, Kongpop (Inventor); Wollack, Edward J. (Inventor); Doiron, Terence (Inventor); Moseley, Samuel H. (Inventor)

    2010-01-01

    The design of a compact low-loss Magic-T is described. The planar Magic-T incorporates a compact microstrip-slotline tee junction and small microstrip-slotline transition area to reduce slotline radiation. The Magic-T produces broadband in-phase and out-of-phase power combiner/divider responses, has low in-band insertion loss, and small in-band phase and amplitude imbalance.

  20. Magical ideation associated social cognition in adolescents: signs of a negative facial affect recognition deficit.

    PubMed

    Canli, Derya; Ozdemir, Hatice; Kocak, Orhan Murat

    2015-08-01

    Studies provide evidence for impaired social cognition in schizotypy and its association with negative symptoms. Cognitive features related to magical ideation - a component of the positive dimension of schizotypy - have been less investigated. We aimed to assess social cognitive functioning among adolescents with high magical ideation scores, mainly focusing on face and emotion recognition. 22 subjects with magical ideation scale scores above the cut off level and 22 controls with lowest scores from among 250 students screened with this scale were included in the study. A face and emotion recognition n-back test, the empathy quotient, theory of mind tests and the Physical Anhedonia Scale were applied to both magical ideation and control groups. The magical ideation group performed significantly worse than controls on both face and emotion recognition tests. Emotion recognition performance was found to be affected by memory load, with sadness, among emotions, revealing a difference between the two groups. Empathy and theory of mind tests did not distinguish the magical ideation group from controls. Our findings provide evidence for a deficit in negative emotion recognition affected by memory load associated with magical ideation in adolescents. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Magical ideation, creativity, handedness, and cerebral asymmetries: a combined behavioural and fMRI study.

    PubMed

    Badzakova-Trajkov, Gjurgjica; Häberling, Isabelle S; Corballis, Michael C

    2011-08-01

    Magical ideation has been shown to be related to measures of hand preference, in which those with mixed handedness exhibit higher levels of magical ideation than those with either consistent left- or right-handedness. It is unclear whether the relation between magical ideation and hand preference is the result of a bias in questionnaire-taking behaviour or of some neuropsychological concomitant of cerebral specialization. We sought to replicate this finding and further investigate how magical ideation is related to other measures of laterality, including handedness based on finger-tapping performance, and cerebral asymmetries for language, spatial judgment, and face processing as revealed by fMRI. Creative achievement was also assessed by questionnaire and correlated with magical ideation and the other measures. Magical ideation and creativity were positively correlated, and both were negatively correlated with absolute hand preference but not with hand performance or with any of the cerebral asymmetries being assessed. The results do not support the notion that the observed association between magical ideation, creativity and hand preference has a neuropsychological explanation based on reduced cerebral lateralization. Copyright © 2011 Elsevier Ltd. All rights reserved.

  2. EarthRef.org: Exploring aspects of a Cyber Infrastructure in Earth Science and Education

    NASA Astrophysics Data System (ADS)

    Staudigel, H.; Koppers, A.; Tauxe, L.; Constable, C.; Helly, J.

    2004-12-01

    EarthRef.org is the common host and (co-) developer of a range of earth science databases and IT resources providing a test bed for a Cyberinfrastructure in Earth Science and Education (CIESE). EarthRef.org data base efforts include in particular the Geochemical Earth Reference Model (GERM), the Magnetics Information Consortium (MagIC), the Educational Resources for Earth Science Education (ERESE) project, the Seamount Catalog, the Mid-Ocean Ridge Catalog, the Radio-Isotope Geochronology (RiG) initiative for CHRONOS, and the Microbial Observatory for Fe oxidizing microbes on Loihi Seamount (FeMO; the most recent development). These diverse databases are developed under a single database umbrella and webserver at the San Diego Supercomputing Center. All the data bases have similar structures, with consistent metadata concepts, a common database layout, and automated upload wizards. Shared resources include supporting databases like an address book, a reference/publication catalog, and a common digital archive making database development and maintenance cost-effective, while guaranteeing interoperability. The EarthRef.org CIESE provides a common umbrella for synthesis information as well as sample-based data, and it bridges the gap between science and science education in middle and high schools, validating the potential for a system wide data infrastructure in a CIESE. EarthRef.org experiences have shown that effective communication with the respective communities is a key part of a successful CIESE facilitating both utility and community buy-in. GERM has been particularly successful at developing a metadata scheme for geochemistry and in the development of a new electronic journal (G-cubed) that has made much progress in data publication and linkages between journals and community data bases. GERM also has worked, through editors and publishers, towards interfacing databases with the publication process, to accomplish a more scholarly and database friendly data publication environment, and to interface with the respective science communities. MagIC has held several workshops that have resulted in an integrated data archival environment using metadata that are interchangeable with the geochemical metadata. MagIC archives a wide array of paleo and rock magnetic directional, intensity and magnetic property data as well as integrating computational tools. ERESE brought together librarians, teachers, and scientists to create an educational environment that supports inquiry driven education and the use of science data. Experiences in EarthRef.org demonstrates the feasibility of an effective, community wide CIESE for data publication, archival and modeling, as well as the outreach to the educational community.

  3. A unified heteronuclear decoupling strategy for magic-angle-spinning solid-state NMR spectroscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Equbal, Asif; Bjerring, Morten; Nielsen, Niels Chr., E-mail: madhu@tifr.res.in, E-mail: ncn@inano.au.dk

    2015-05-14

    A unified strategy of two-pulse based heteronuclear decoupling for solid-state magic-angle spinning nuclear magnetic resonance is presented. The analysis presented here shows that different decoupling sequences like two-pulse phase-modulation (TPPM), X-inverse-X (XiX), and finite pulse refocused continuous wave (rCW{sup A}) are basically specific solutions of a more generalized decoupling scheme which incorporates the concept of time-modulation along with phase-modulation. A plethora of other good decoupling conditions apart from the standard, TPPM, XiX, and rCW{sup A} decoupling conditions are available from the unified decoupling approach. The importance of combined time- and phase-modulation in order to achieve the best decoupling conditions ismore » delineated. The consequences of different indirect dipolar interactions arising from cross terms comprising of heteronuclear and homonuclear dipolar coupling terms and also those between heteronuclear dipolar coupling and chemical-shift anisotropy terms are presented in order to unfold the effects of anisotropic interactions under different decoupling conditions. Extensive numerical simulation results are corroborated with experiments on standard amino acids.« less

  4. Measurement of sample temperatures under magic-angle spinning from the chemical shift and spin-lattice relaxation rate of 79Br in KBr powder

    PubMed Central

    Thurber, Kent R.; Tycko, Robert

    2009-01-01

    Accurate determination of sample temperatures in solid state nuclear magnetic resonance (NMR) with magic-angle spinning (MAS) can be problematic, particularly because frictional heating and heating by radio-frequency irradiation can make the internal sample temperature significantly different from the temperature outside the MAS rotor. This paper demonstrates the use of 79Br chemical shifts and spin-lattice relaxation rates in KBr powder as temperature-dependent parameters for the determination of internal sample temperatures. Advantages of this method include high signal-to-noise, proximity of the 79Br NMR frequency to that of 13C, applicability from 20 K to 320 K or higher, and simultaneity with adjustment of the MAS axis direction. We show that spin-lattice relaxation in KBr is driven by a quadrupolar mechanism. We demonstrate a simple approach to including KBr powder in hydrated samples, such as biological membrane samples, hydrated amyloid fibrils, and hydrated microcrystalline proteins, that allows direct assessment of the effects of frictional and radio-frequency heating under experimentally relevant conditions. PMID:18930418

  5. Measurement of sample temperatures under magic-angle spinning from the chemical shift and spin-lattice relaxation rate of 79Br in KBr powder.

    PubMed

    Thurber, Kent R; Tycko, Robert

    2009-01-01

    Accurate determination of sample temperatures in solid state nuclear magnetic resonance (NMR) with magic-angle spinning (MAS) can be problematic, particularly because frictional heating and heating by radio-frequency irradiation can make the internal sample temperature significantly different from the temperature outside the MAS rotor. This paper demonstrates the use of (79)Br chemical shifts and spin-lattice relaxation rates in KBr powder as temperature-dependent parameters for the determination of internal sample temperatures. Advantages of this method include high signal-to-noise, proximity of the (79)Br NMR frequency to that of (13)C, applicability from 20 K to 320 K or higher, and simultaneity with adjustment of the MAS axis direction. We show that spin-lattice relaxation in KBr is driven by a quadrupolar mechanism. We demonstrate a simple approach to including KBr powder in hydrated samples, such as biological membrane samples, hydrated amyloid fibrils, and hydrated microcrystalline proteins, that allows direct assessment of the effects of frictional and radio-frequency heating under experimentally relevant conditions.

  6. Old and New Magic Numbers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Talmi, Igal

    2008-11-11

    The discovery of magic numbers led to the shell model. They indicated closure of major shells and are robust: proton magic numbers are rather independent of the occupation of neutron orbits and vice versa. Recently the magic property became less stringent and we hear a lot about the discovery of new magic numbers. These, however, indicate sub-shell closures and strongly depend on occupation numbers and hence, may be called quasi-magic numbers. Some of these have been known for many years and the mechanism for their appearance as well as disappearance, was well understood within the simple shell model. The situationmore » will be illustrated by a few examples which demonstrate the simple features of the shell model. Will this simplicity emerge from the complex computations of nuclear many-body theory?.« less

  7. The magic words: Using computers to uncover mental associations for use in magic trick design.

    PubMed

    Williams, Howard; McOwan, Peter W

    2017-01-01

    The use of computational systems to aid in the design of magic tricks has been previously explored. Here further steps are taken in this direction, introducing the use of computer technology as a natural language data sourcing and processing tool for magic trick design purposes. Crowd sourcing of psychological concepts is investigated; further, the role of human associative memory and its exploitation in magical effects is explored. A new trick is developed and evaluated: a physical card trick partially designed by a computational system configured to search for and explore conceptual spaces readily understood by spectators.

  8. Magnetic Moments in the Past: developing archaeomagnetic dating in the UK

    NASA Astrophysics Data System (ADS)

    Outram, Zoe; Batt, Catherine M.; Linford, Paul

    2010-05-01

    Magnetic studies of archaeological materials have a long history of development in the UK and the data produced by these studies is a key component of global models of the geomagnetic field. However, archaeomagnetic dating is not a widely used dating technique in UK archaeology, despite the potential to produce archaeologically significant information that directly relates to human activity. This often means that opportunities to improve our understanding of the past geomagnetic field are lost, because archaeologists are unaware of the potential of the method. This presentation discusses a project by the University of Bradford, UK and English Heritage to demonstrate and communicate the potential of archaeomagnetic dating of archaeological materials for routine use within the UK. The aims of the project were achieved through the production of a website and a database for all current and past archaeomagnetic studies carried out in the UK. The website provides archaeologists with the information required to consider the use of archaeomagnetic dating; including a general introduction to the technique, the features that can be sampled, the precision that can be expected from the dates and how much it costs. In addition, all archaeomagnetic studies carried out in the UK have been collated into a database, allowing similar studies to be identified on the basis of the location of the sites, the archaeological period and type of feature sampled. This clearly demonstrates how effective archaeomagnetic dating has been in different archaeological situations. The locations of the sites have been mapped using Google Earth so that studies carried out in a particular region, or from a specific time period can be easily identified. The database supports the continued development of archaeomagnetic dating in the UK, as the data required to construct the secular variation curves can be extracted easily. This allows the curves to be regularly updated following the production of new magnetic measurements. The information collated within the database will also be added to the global databases, such as MaGIC, contributing the improvement of the global models of the geomagnetic field. This project demonstrates the benefits that the presentation of clear, accessible information and increased communication with archaeologists can have on the study of the geomagnetic field. It is also hoped that similar approaches will beintroduced on a wider geographical scale in the future.

  9. Mathematical Construction of Magic Squares Utilizing Base-N Arithmetic

    ERIC Educational Resources Information Center

    O'Brien, Thomas D.

    2006-01-01

    Magic squares have been of interest as a source of recreation for over 4,500 years. A magic square consists of a square array of n[squared] positive and distinct integers arranged so that the sum of any column, row, or main diagonal is the same. In particular, an array of consecutive integers from 1 to n[squared] forming an nxn magic square is…

  10. Simulations of Large-Area Electron Beam Diodes

    NASA Astrophysics Data System (ADS)

    Swanekamp, S. B.; Friedman, M.; Ludeking, L.; Smithe, D.; Obenschain, S. P.

    1999-11-01

    Large area electron beam diodes are typically used to pump the amplifiers of KrF lasers. Simulations of large-area electron beam diodes using the particle-in-cell code MAGIC3D have shown the electron flow in the diode to be unstable. Since this instability can potentially produce a non-uniform current and energy distribution in the hibachi structure and lasing medium it can be detrimental to laser efficiency. These results are similar to simulations performed using the ISIS code.(M.E. Jones and V.A. Thomas, Proceedings of the 8^th) International Conference on High-Power Particle Beams, 665 (1990). We have identified the instability as the so called ``transit-time" instability(C.K. Birdsall and W.B. Bridges, Electrodynamics of Diode Regions), (Academic Press, New York, 1966).^,(T.M. Antonsen, W.H. Miner, E. Ott, and A.T. Drobot, Phys. Fluids 27), 1257 (1984). and have investigated the role of the applied magnetic field and diode geometry. Experiments are underway to characterize the instability on the Nike KrF laser system and will be compared to simulation. Also some possible ways to mitigate the instability will be presented.

  11. Q-Speciation and Network Structure Evolution in Invert Calcium Silicate Glasses.

    PubMed

    Kaseman, Derrick C; Retsinas, A; Kalampounias, A G; Papatheodorou, G N; Sen, S

    2015-07-02

    Binary silicate glasses in the system CaO-SiO2 are synthesized over an extended composition range (42 mol % ≤ CaO ≤ 61 mol %), using container-less aerodynamic levitation techniques and CO2-laser heating. The compositional evolution of Q speciation in these glasses is quantified using (29)Si and (17)O magic angle spinning nuclear magnetic resonance spectroscopy. The results indicate progressive depolymerization of the silicate network upon addition of CaO and significant deviation of the Q speciation from the binary model. The equilibrium constants for the various Q species disproportionation reactions for these glasses are found to be similar to (much smaller than) those characteristic of Li (Mg)-silicate glasses, consistent with the corresponding trends in the field strengths of these modifier cations. Increasing CaO concentration results in an increase in the packing density and structural rigidity of these glasses and consequently in their glass transition temperature Tg. This apparent role reversal of conventional network-modifying cations in invert alkaline-earth silicate glasses are compared and contrasted with that in their alkali silicate counterparts.

  12. Continuous Faraday measurement of spin precession without light shifts

    NASA Astrophysics Data System (ADS)

    Jasperse, M.; Kewming, M. Â. J.; Fischer, S. Â. N.; Pakkiam, P.; Anderson, R. Â. P.; Turner, L. Â. D.

    2017-12-01

    We describe a dispersive Faraday optical probe of atomic spin which performs a weak measurement of spin projection of a quantum gas continuously for more than one second. To date, focusing bright far-off-resonance probes onto quantum gases has proved invasive due to strong scalar and vector light shifts exerting dipole and Stern-Gerlach forces. We show that tuning the probe near the magic-zero wavelength at 790 nm between the fine-structure doublet of 87Rb cancels the scalar light shift, and careful control of polarization eliminates the vector light shift. Faraday rotations due to each fine-structure line reinforce at this wavelength, enhancing the signal-to-noise ratio for a fixed rate of probe-induced decoherence. Using this minimally invasive spin probe, we perform microscale atomic magnetometry at high temporal resolution. Spectrogram analysis of the Larmor precession signal of a single spinor Bose-Einstein condensate measures a time-varying magnetic field strength with 1 μ G accuracy every 5 ms; or, equivalently, makes more than 200 successive measurements each at 10 pT /√{Hz } sensitivity.

  13. Magical ideation -- defense mechanism or neuropathology? A study with multiple sclerosis patients.

    PubMed

    te Wildt, Bert Theodor; Schultz-Venrath, Ulrich

    2004-01-01

    The major psychological stress factor in multiple sclerosis (MS) is loss of control of life. In MS patients with impaired cognition, magical ideation might be a characteristic way of thinking. Proof for this may be the high frequency of alternative treatments used by individuals with MS. The study investigates whether the level of magical ideation in MS patients is higher compared to healthy control subjects and, in case of positive confirmation, with which somatic and psychological features it is associated. Moreover, it is aimed to discuss the modalities of magical ideation in general. A German version of the Magical Ideation Scale was validated with a group of 69 healthy subjects. Ninety-four MS patients were additionally assessed with the Dissociative Experience Scale, the Symptom-Check-List-90-Revised and 5 neuropsychological tests. The Magical Ideation Scale did not reveal a significant difference between MS patients and healthy controls (p = 0.968). Among the MS patients, magical ideation shows a correlation neither with age nor with disability, but a positive correlation (p = 0.007; r = 0.329) with the grade of neuropsychological deficiency. Among the psychological parameters, the highest positive correlation with magical ideation was found in dissociation (p = 0.000; r = 0.520). Magical ideation, sharing common features with dissociation, can be viewed as an early defense mechanism when perceiving a loss of control of life, particularly in early stages of MS. In late stages, when developing neuropsychological deficits, it may occur as a substitute for cognitive coping. The data may encourage clinicians to identify magical ideation. In young and previously diagnosed patients, it is important to acknowledge helplessness and support a rather rational way of coping. Training cognitive skills could be crucial to prevent older patients from losing touch with reality. More generally, the occurrence of a significant amount of magical ideation is discussed both as a psychological and a neurophysiologic regression of thinking. Copyright 2004 S. Karger AG, Basel

  14. A quasi-optical and corrugated waveguide microwave transmission system for simultaneous dynamic nuclear polarization NMR on two separate 14.1 T spectrometers

    PubMed Central

    Dubroca, Thierry; Smith, Adam N.; Pike, Kevin J.; Froud, Stuart; Wylde, Richard; Trociewitz, Bianca; McKay, Johannes; Mentink-Vigier, Frederic; van Tol, Johan; Wi, Sungsool; Brey, William; Long, Joanna R.; Frydman, Lucio; Hill, Stephen

    2018-01-01

    Nuclear magnetic resonance (NMR) is an intrinsically insensitive technique, with Boltzmann distributions of nuclear spin states on the order of parts per million in conventional magnetic fields. To overcome this limitation, dynamic nuclear polarization (DNP) can be used to gain up to three orders of magnitude in signal enhancement, which can decrease experimental time by up to six orders of magnitude. In DNP experiments, nuclear spin polarization is enhanced by transferring the relatively larger electron polarization to NMR active nuclei via microwave irradiation. Here, we describe the design and performance of a quasi-optical system enabling the use of a single 395 GHz gyrotron microwave source to simultaneously perform DNP experiments on two different 14.1 T (1H 600 MHz) NMR spectrometers: one configured for magic angle spinning (MAS) solid state NMR; the other configured for solution state NMR experiments. In particular, we describe how the high power microwave beam is split, transmitted, and manipulated between the two spectrometers. A 13C enhancement of 128 is achieved via the cross effect for alanine, using the nitroxide biradical AMUPol, under MAS-DNP conditions at 110 K, while a 31P enhancement of 160 is achieved via the Overhauser effect for triphenylphosphine using the monoradical BDPA under solution NMR conditions at room temperature. The latter result is the first demonstration of Overhauser DNP in the solution state at a field of 14.1 T (1H 600 MHz). Moreover these results have been produced with large sample volumes (~100 μL, i.e. 3 mm diameter NMR tubes). PMID:29459343

  15. On the crystal structure of the vaterite polymorph of CaCO3: a calcium-43 solid-state NMR and computational assessment.

    PubMed

    Burgess, Kevin M N; Bryce, David L

    2015-02-01

    The vaterite polymorph of CaCO3 has puzzled crystallographers for decades in part due to difficulties in obtaining single crystals. The multiple proposed structures for the vaterite polymorph of CaCO3 are assessed using a combined (43)Ca solid-state nuclear magnetic resonance (SSNMR) spectroscopic and computational approach. A combination of improved experimental and computational methods, along with a calibrated chemical shift scale and (43)Ca nuclear quadrupole moment, allow for improved insights relative to our earlier work (Bryce et al., J. Am. Chem. Soc. 2008, 130, 9282). Here, we synthesize a (43)Ca isotopically-enriched sample of vaterite and perform high-resolution quadrupolar SSNMR experiments including magic-angle spinning (MAS), double-rotation (DOR), and multiple-quantum (MQ) MAS experiments at magnetic field strengths of 9.4 and 21.1T. We identify one crystallographically unique Ca(2+) site in vaterite with a slight distribution in both chemical shifts and quadrupolar parameters. Both the experimental (43)Ca electric field gradient tensor and the isotropic chemical shift for vaterite are compared to those calculated with the gauge-including projector-augmented-wave (GIPAW) DFT method in an attempt to identify the model that best represents the crystal structure of vaterite. Simulations of (43)Ca DOR and MAS NMR spectra based on the NMR parameters computed for a total of 18 structural models for vaterite allow us to distinguish between these models. Among these 18, the P3221 and C2 structures provide simulated spectra and diffractograms in best agreement with all experimental data. Copyright © 2014 Elsevier Inc. All rights reserved.

  16. A quasi-optical and corrugated waveguide microwave transmission system for simultaneous dynamic nuclear polarization NMR on two separate 14.1 T spectrometers

    NASA Astrophysics Data System (ADS)

    Dubroca, Thierry; Smith, Adam N.; Pike, Kevin J.; Froud, Stuart; Wylde, Richard; Trociewitz, Bianca; McKay, Johannes; Mentink-Vigier, Frederic; van Tol, Johan; Wi, Sungsool; Brey, William; Long, Joanna R.; Frydman, Lucio; Hill, Stephen

    2018-04-01

    Nuclear magnetic resonance (NMR) is an intrinsically insensitive technique, with Boltzmann distributions of nuclear spin states on the order of parts per million in conventional magnetic fields. To overcome this limitation, dynamic nuclear polarization (DNP) can be used to gain up to three orders of magnitude in signal enhancement, which can decrease experimental time by up to six orders of magnitude. In DNP experiments, nuclear spin polarization is enhanced by transferring the relatively larger electron polarization to NMR active nuclei via microwave irradiation. Here, we describe the design and performance of a quasi-optical system enabling the use of a single 395 GHz gyrotron microwave source to simultaneously perform DNP experiments on two different 14.1 T (1H 600 MHz) NMR spectrometers: one configured for magic angle spinning (MAS) solid state NMR; the other configured for solution state NMR experiments. In particular, we describe how the high power microwave beam is split, transmitted, and manipulated between the two spectrometers. A 13C enhancement of 128 is achieved via the cross effect for alanine, using the nitroxide biradical AMUPol, under MAS-DNP conditions at 110 K, while a 31P enhancement of 160 is achieved via the Overhauser effect for triphenylphosphine using the monoradical BDPA under solution NMR conditions at room temperature. The latter result is the first demonstration of Overhauser DNP in the solution state at a field of 14.1 T (1H 600 MHz). Moreover these results have been produced with large sample volumes (∼100 μL, i.e. 3 mm diameter NMR tubes).

  17. A quasi-optical and corrugated waveguide microwave transmission system for simultaneous dynamic nuclear polarization NMR on two separate 14.1 T spectrometers.

    PubMed

    Dubroca, Thierry; Smith, Adam N; Pike, Kevin J; Froud, Stuart; Wylde, Richard; Trociewitz, Bianca; McKay, Johannes; Mentink-Vigier, Frederic; van Tol, Johan; Wi, Sungsool; Brey, William; Long, Joanna R; Frydman, Lucio; Hill, Stephen

    2018-04-01

    Nuclear magnetic resonance (NMR) is an intrinsically insensitive technique, with Boltzmann distributions of nuclear spin states on the order of parts per million in conventional magnetic fields. To overcome this limitation, dynamic nuclear polarization (DNP) can be used to gain up to three orders of magnitude in signal enhancement, which can decrease experimental time by up to six orders of magnitude. In DNP experiments, nuclear spin polarization is enhanced by transferring the relatively larger electron polarization to NMR active nuclei via microwave irradiation. Here, we describe the design and performance of a quasi-optical system enabling the use of a single 395 GHz gyrotron microwave source to simultaneously perform DNP experiments on two different 14.1 T ( 1 H 600 MHz) NMR spectrometers: one configured for magic angle spinning (MAS) solid state NMR; the other configured for solution state NMR experiments. In particular, we describe how the high power microwave beam is split, transmitted, and manipulated between the two spectrometers. A 13 C enhancement of 128 is achieved via the cross effect for alanine, using the nitroxide biradical AMUPol, under MAS-DNP conditions at 110 K, while a 31 P enhancement of 160 is achieved via the Overhauser effect for triphenylphosphine using the monoradical BDPA under solution NMR conditions at room temperature. The latter result is the first demonstration of Overhauser DNP in the solution state at a field of 14.1 T ( 1 H 600 MHz). Moreover these results have been produced with large sample volumes (∼100 µL, i.e. 3 mm diameter NMR tubes). Copyright © 2018 Elsevier Inc. All rights reserved.

  18. Magnetic pair creation transparency in gamma-ray pulsars

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Story, Sarah A.; Baring, Matthew G., E-mail: ss16@rice.edu, E-mail: baring@rice.edu

    2014-07-20

    Magnetic pair creation, γ → e {sup +} e {sup –}, has been at the core of radio pulsar paradigms and central to polar cap models of gamma-ray pulsars for over three decades. The Fermi gamma-ray pulsar population now exceeds 140 sources and has defined an important part of Fermi's science legacy, providing rich information for the interpretation of young energetic pulsars and old millisecond pulsars. Among the population characteristics well established is the common occurrence of exponential turnovers in their spectra in the 1-10 GeV range. These turnovers are too gradual to arise from magnetic pair creation in themore » strong magnetic fields of pulsar inner magnetospheres. By demanding insignificant photon attenuation precipitated by such single-photon pair creation, the energies of these turnovers for Fermi pulsars can be used to compute lower bounds for the typical altitude of GeV band emission. This paper explores such pair transparency constraints below the turnover energy and updates earlier altitude bound determinations that have been deployed in various Fermi pulsar papers. For low altitude emission locales, general relativistic influences are found to be important, increasing cumulative opacity, shortening the photon attenuation lengths, and also reducing the maximum energy that permits escape of photons from a neutron star magnetosphere. Rotational aberration influences are also explored, and are found to be small at low altitudes, except near the magnetic pole. The analysis presented in this paper clearly demonstrates that including near-threshold physics in the pair creation rate is essential to deriving accurate attenuation lengths and escape energies. The altitude bounds are typically in the range of 2-7 stellar radii for the young Fermi pulsar population, and provide key information on the emission altitude in radio quiet pulsars that do not possess double-peaked pulse profiles. The bound for the Crab pulsar is at a much higher altitude, with the putative detection by MAGIC out to 350-400 GeV implying a lower bound of 310 km to the emission region, i.e., approximately 20% of the light cylinder radius. These results are also extended to the super-critical field domain, where it is found that emission in neurton stars originating below around 10 stellar radii will not appear in the Fermi-LAT band.« less

  19. Magnetic Pair Creation Transparency in Gamma-Ray Pulsars

    NASA Astrophysics Data System (ADS)

    Story, Sarah A.; Baring, Matthew G.

    2014-07-01

    Magnetic pair creation, γ → e + e -, has been at the core of radio pulsar paradigms and central to polar cap models of gamma-ray pulsars for over three decades. The Fermi gamma-ray pulsar population now exceeds 140 sources and has defined an important part of Fermi's science legacy, providing rich information for the interpretation of young energetic pulsars and old millisecond pulsars. Among the population characteristics well established is the common occurrence of exponential turnovers in their spectra in the 1-10 GeV range. These turnovers are too gradual to arise from magnetic pair creation in the strong magnetic fields of pulsar inner magnetospheres. By demanding insignificant photon attenuation precipitated by such single-photon pair creation, the energies of these turnovers for Fermi pulsars can be used to compute lower bounds for the typical altitude of GeV band emission. This paper explores such pair transparency constraints below the turnover energy and updates earlier altitude bound determinations that have been deployed in various Fermi pulsar papers. For low altitude emission locales, general relativistic influences are found to be important, increasing cumulative opacity, shortening the photon attenuation lengths, and also reducing the maximum energy that permits escape of photons from a neutron star magnetosphere. Rotational aberration influences are also explored, and are found to be small at low altitudes, except near the magnetic pole. The analysis presented in this paper clearly demonstrates that including near-threshold physics in the pair creation rate is essential to deriving accurate attenuation lengths and escape energies. The altitude bounds are typically in the range of 2-7 stellar radii for the young Fermi pulsar population, and provide key information on the emission altitude in radio quiet pulsars that do not possess double-peaked pulse profiles. The bound for the Crab pulsar is at a much higher altitude, with the putative detection by MAGIC out to 350-400 GeV implying a lower bound of 310 km to the emission region, i.e., approximately 20% of the light cylinder radius. These results are also extended to the super-critical field domain, where it is found that emission in magnetars originating below around 10 stellar radii will not appear in the Fermi-LAT band.

  20. Children's and adults' reactions to magical and ordinary suggestion: are suggestibility and magical thinking psychologically close relatives?

    PubMed

    Subbotsky, Eugene

    2007-11-01

    In Experiment 1, 6- and 9-year-old children and adults were asked to imagine various types of objects. The experimenter then attempted to change the image of those objects in participants' minds by either suggesting that the objects may change against the participants' will, or by asking participants to change the objects as a favor to the experimenter. Two types of suggestive causation were employed: Magical-suggestion (a magic spell was cast with the aim of changing the imagined objects) and ordinary-suggestion (participants were told that the objects in their minds could alter against their will). Ordinary-suggestion was as effective as magical-suggestion in changing the participants' imagined objects. For adults, a direct request for compliance produced a stronger effect than did magical suggestion. This effect was not found in children. In Experiment 2, the two types of suggestion were tested on an alternative type of imagined objects. Adult participants were asked to imagine their futures. It was then proposed that (a) a magic spell could be cast on their futures with the aim of changing them either for the worse or for the better (magical-suggestion), or (b) changing a numerical pattern on a computer screen could change their futures (ordinary-suggestion). All participants denied that changing a numerical pattern on a computer screen could affect their lives, yet in their actions they demonstrated an element of belief in this possibility. As in Experiment 1, in Experiment 2 ordinary suggestion was as effective as magical suggestion. The hypothesis of an historic contiguity between magical causality and ordinary suggestion is discussed.

  1. Self-consistent evolution of plasma discharge and electromagnetic fields in a microwave pulse compressor

    NASA Astrophysics Data System (ADS)

    Shlapakovski, A. S.; Beilin, L.; Hadas, Y.; Schamiloglu, E.; Krasik, Ya. E.

    2015-07-01

    Nanosecond-scale evolution of plasma and RF electromagnetic fields during the release of energy from a microwave pulse compressor with a plasma interference switch was investigated numerically using the code MAGIC. The plasma was simulated in the scope of the gas conductivity model in MAGIC. The compressor embodied an S-band cavity and H-plane waveguide tee with a shorted side arm filled with pressurized gas. In a simplified approach, the gas discharge was initiated by setting an external ionization rate in a layer crossing the side arm waveguide in the location of the electric field antinode. It was found that with increasing ionization rate, the microwave energy absorbed by the plasma in the first few nanoseconds increases, but the absorption for the whole duration of energy release, on the contrary, decreases. In a hybrid approach modeling laser ignition of the discharge, seed electrons were set around the electric field antinode. In this case, the plasma extends along the field forming a filament and the plasma density increases up to the level at which the electric field within the plasma decreases due to the skin effect. Then, the avalanche rate decreases but the density still rises until the microwave energy release begins and the electric field becomes insufficient to support the avalanche process. The extraction of the microwave pulse limits its own power by terminating the rise of the plasma density and filament length. For efficient extraction, a sufficiently long filament of dense plasma must have sufficient time to be formed.

  2. A Note on Magic Squares

    ERIC Educational Resources Information Center

    Williams, Horace E.

    1974-01-01

    A method for generating 3x3 magic squares is developed. A series of questions relating to these magic squares is posed. An invesitgation using matrix methods is suggested with some questions for consideration. (LS)

  3. The Versatile Magic Square.

    ERIC Educational Resources Information Center

    Watson, Gale A.

    2003-01-01

    Demonstrates the transformations that are possible to construct a variety of magic squares, including modifications to challenge students from elementary grades through algebra. Presents an example of using magic squares with students who have special needs. (YDS)

  4. Application of the Internet of Things

    NASA Astrophysics Data System (ADS)

    Qin, Xiaming; Zhang, Guoqing

    2011-12-01

    The Internet of Things is not yet very widespread, many people have little information about Internet of things. But, for magical properties of the Internet of things , its appearance immediately aroused people's great interest. This paper, aiming application of the Internet of Things , use AHP to analyze and look forward to prospects of IOT in many fields.

  5. Magic Angle Spinning NMR Metabolomics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhi Hu, Jian

    Nuclear Magnetic Resonance (NMR) spectroscopy is a non-destructive, quantitative, reproducible, untargeted and unbiased method that requires no or minimal sample preparation, and is one of the leading analytical tools for metabonomics research [1-3]. The easy quantification and the no need of prior knowledge about compounds present in a sample associated with NMR are advantageous over other techniques [1,4]. 1H NMR is especially attractive because protons are present in virtually all metabolites and its NMR sensitivity is high, enabling the simultaneous identification and monitoring of a wide range of low molecular weight metabolites.

  6. Differential network analysis reveals the genome-wide landscape of estrogen receptor modulation in hormonal cancers

    PubMed Central

    Hsiao, Tzu-Hung; Chiu, Yu-Chiao; Hsu, Pei-Yin; Lu, Tzu-Pin; Lai, Liang-Chuan; Tsai, Mong-Hsun; Huang, Tim H.-M.; Chuang, Eric Y.; Chen, Yidong

    2016-01-01

    Several mutual information (MI)-based algorithms have been developed to identify dynamic gene-gene and function-function interactions governed by key modulators (genes, proteins, etc.). Due to intensive computation, however, these methods rely heavily on prior knowledge and are limited in genome-wide analysis. We present the modulated gene/gene set interaction (MAGIC) analysis to systematically identify genome-wide modulation of interaction networks. Based on a novel statistical test employing conjugate Fisher transformations of correlation coefficients, MAGIC features fast computation and adaption to variations of clinical cohorts. In simulated datasets MAGIC achieved greatly improved computation efficiency and overall superior performance than the MI-based method. We applied MAGIC to construct the estrogen receptor (ER) modulated gene and gene set (representing biological function) interaction networks in breast cancer. Several novel interaction hubs and functional interactions were discovered. ER+ dependent interaction between TGFβ and NFκB was further shown to be associated with patient survival. The findings were verified in independent datasets. Using MAGIC, we also assessed the essential roles of ER modulation in another hormonal cancer, ovarian cancer. Overall, MAGIC is a systematic framework for comprehensively identifying and constructing the modulated interaction networks in a whole-genome landscape. MATLAB implementation of MAGIC is available for academic uses at https://github.com/chiuyc/MAGIC. PMID:26972162

  7. Bound states for magic state distillation in fault-tolerant quantum computation.

    PubMed

    Campbell, Earl T; Browne, Dan E

    2010-01-22

    Magic state distillation is an important primitive in fault-tolerant quantum computation. The magic states are pure nonstabilizer states which can be distilled from certain mixed nonstabilizer states via Clifford group operations alone. Because of the Gottesman-Knill theorem, mixtures of Pauli eigenstates are not expected to be magic state distillable, but it has been an open question whether all mixed states outside this set may be distilled. In this Letter we show that, when resources are finitely limited, nondistillable states exist outside the stabilizer octahedron. In analogy with the bound entangled states, which arise in entanglement theory, we call such states bound states for magic state distillation.

  8. The magic words: Using computers to uncover mental associations for use in magic trick design

    PubMed Central

    2017-01-01

    The use of computational systems to aid in the design of magic tricks has been previously explored. Here further steps are taken in this direction, introducing the use of computer technology as a natural language data sourcing and processing tool for magic trick design purposes. Crowd sourcing of psychological concepts is investigated; further, the role of human associative memory and its exploitation in magical effects is explored. A new trick is developed and evaluated: a physical card trick partially designed by a computational system configured to search for and explore conceptual spaces readily understood by spectators. PMID:28792941

  9. Magic Physics?

    ERIC Educational Resources Information Center

    Featonby, David

    2010-01-01

    This article examines several readily available "magic tricks" which base their "trickery" on physics principles, and questions the use of the word "magic" in the 21st century, both in popular children's science and in everyday language. (Contains 18 figures.)

  10. Magical thinking and memory: distinctiveness effect for tv commercials with magical content.

    PubMed

    Subbotsky, Eugene; Mathews, Jayne

    2011-10-01

    The aim of this study was to examine whether memorizing advertised products of television advertisements with magical effects (i.e., talking animals, inanimate objects which turn into humans, objects that appear from thin air or instantly turn into other objects) is easier than memorizing products of advertisements without such effects, by testing immediate and delayed retention. Adolescents and adults viewed two films containing television advertisements and were asked to recall and recognize the films' characters, events, and advertised products. Film 1 included magical effects, but Film 2 did not. On a free-recall test, no differences in the number of items recalled were noted for the two films. On the immediate recognition test, adolescents, but not adults, showed significantly better recognition for the magical than the nonmagical film. When this test was repeated two weeks later, results were reversed: adults, but not adolescents, recognized a significantly larger number of items from the magical film than the nonmagical one. These results are interpreted to accentuate the role of magical thinking in cognitive processes.

  11. MAGIC Computer Simulation. Volume 2: Analyst Manual, Part 1

    DTIC Science & Technology

    1971-05-01

    A review of the subject Magic Computer Simulation User and Analyst Manuals has been conducted based upon a request received from the US Army...1971 4. TITLE AND SUBTITLE MAGIC Computer Simulation Analyst Manual Part 1 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...14. ABSTRACT The MAGIC computer simulation generates target description data consisting of item-by-item listings of the target’s components and air

  12. NTRFACE for MAGIC

    DTIC Science & Technology

    1989-07-31

    40. NO NO ACCESSION NO N7 ?I TITLE (inWijuod Security Claisification) NTRFACE FOR MAGIC 𔃼 PERSONAL AUTHOR(S) N.T. GLADD PE OF REPORT T b TIME...the MAGIC Particle-in-Cell Simulation Code. 19 ABSTRACT (Contianue on reverse if nceary and d ntiy by block number) The NTRFACE system was developed...made concret by applying it to a specific application- a mature, highly complex plasma physics particle in cell simulation code name MAGIC . This

  13. Evaluation of magical thinking: validation of the Illusory Beliefs Inventory.

    PubMed

    Shihata, Sarah; Egan, Sarah J; Rees, Clare S

    2014-01-01

    Magical thinking has been related to obsessive-compulsive disorder; yet, little research has examined this construct in other anxiety disorders. The Illusory Beliefs Inventory (IBI) is a recently developed measure of magical thinking. The aim of this study was to investigate the psychometric properties of this new measure and to determine if magical thinking accounts for pathological worry beyond the well-researched constructs of intolerance of uncertainty (IU) and perfectionism. A sample of 502 participants completed an online survey. Confirmatory factor analysis identified a three-factor solution for the IBI, and the measure had good internal consistency (α = .92), test-retest reliability (r = .94) and discriminant validity. Magical thinking, IU, and perfectionism all predicted pathological worry; however, magical thinking accounted for less than 1% of unique variance in worry, suggesting that it is not strongly related to worry. Further investigation regarding the validity and clinical utility of the IBI is required.

  14. 13C-13C dipolar recoupling under very fast magic angle spinning in solid-state nuclear magnetic resonance: Applications to distance measurements, spectral assignments, and high-throughput secondary-structure determination

    NASA Astrophysics Data System (ADS)

    Ishii, Yoshitaka

    2001-05-01

    A technique is presented to recouple homonuclear dipolar couplings between dilute spin pairs such as 13C-13C systems under very fast magic angle spinning (MAS) in solid-state nuclear magnetic resonance (NMR) spectroscopy. The presented technique, finite pulse rf driven recoupling (fpRFDR), restores homonuclear dipolar interactions based on constructive usage of finite pulse-width effects in a phase- and symmetry-cycled π-pulse train in which a rotor-synchronous π pulse is applied every rotation period. The restored effective dipolar interaction has the form of a zero-quantum dipolar Hamiltonian for static solids, whose symmetry in spin space is different from that obtained by conventional rf driven recoupling (RFDR) techniques. It is demonstrated that the efficiency of recoupling by fpRFDR is not strongly dependent on chemical shift differences or resonance offsets in contrast to previous recoupling methods under very fast MAS. To realize distance measurements without effects of spin relaxation, a constant-time version of fpRFDR (CT-fpRFDR) is introduced, in which the effective evolution period is varied by refocusing dipolar evolution with a rotor-synchronized solid echo while the total recoupling period is kept constant. From CT-fpRFDR experiments at a spinning speed of 30.3 kHz in a field of 17.6 T, the 13C-13C distance of [1-13C]Ala-[1-13C]Gly-Gly was determined to be 3.27 Å, which agrees well with the value of 3.20 Å obtained by x-ray diffraction. Also, two-dimensional (2D) 13C/13C chemical-shift correlation NMR spectrum in a field of 9.4 T was obtained with fpRFDR for fibrils of the segmentally 13C- and 15N-labeled Alzheimer's β-Amyloid fragments, Aβ16-22 (residues 16-22 taken from the 40-residue Aβ peptide) in which Leu-17 through Ala-21 are uniformly 13C- and 15N-labeled. Most 13C resonances for the main chain as well as for the side chains are assigned based on 2D 13C/13C chemical-shift correlation patterns specific to amino-acid types. Examination of the obtained 13C chemical shifts revealed the formation of β-strand across the entire molecule of Aβ16-22. Possibility of high throughput determination of global main-chain structures based on 13C shifts obtained from 2D 13C/13C chemical-shift correlation under very fast MAS is also discussed for uniformly/segmentally 13C-labeled protein/peptide samples.

  15. Met-Activating Genetically Improved Chimeric Factor-1 Promotes Angiogenesis and Hypertrophy in Adult Myogenesis.

    PubMed

    Ronzoni, Flavio; Ceccarelli, Gabriele; Perini, Ilaria; Benedetti, Laura; Galli, Daniela; Mulas, Francesca; Balli, Martina; Magenes, Giovanni; Bellazzi, Riccardo; De Angelis, Gabriella C; Sampaolesi, Maurilio

    2017-01-01

    Myogenic progenitor cells (activated satellite cells) are able to express both HGF and its receptor cMet. After muscle injury, HGF-Met stimulation promotes activation and primary division of satellite cells. MAGIC-F1 (Met-Activating Genetically Improved Chimeric Factor-1) is an engineered protein that contains two human Met-binding domains that promotes muscle hypertrophy. MAGIC-F1 protects myogenic precursors against apoptosis and increases their fusion ability enhancing muscle differentiation. Hemizygous and homozygous Magic-F1 transgenic mice displayed constitutive muscle hypertrophy. Here we describe microarray analysis on Magic-F1 myogenic progenitor cells showing an altered gene signatures on muscular hypertrophy and angiogenesis compared to wild-type cells. In addition, we performed a functional analysis on Magic-F1+/+ transgenic mice versus controls using treadmill test. We demonstrated that Magic-F1+/+ mice display an increase in muscle mass and cross-sectional area leading to an improvement in running performance. Moreover, the presence of MAGIC-F1 affected positively the vascular network, increasing the vessel number in fast twitch fibers. Finally, the gene expression profile analysis of Magic-F1+/+ satellite cells evidenced transcriptomic changes in genes involved in the control of muscle growth, development and vascularisation. We showed that MAGIC-F1-induced muscle hypertrophy affects positively vascular network, increasing vessel number in fast twitch fibers. This was due to unique features of mammalian skeletal muscle and its remarkable ability to adapt promptly to different physiological demands by modulating the gene expression profile in myogenic progenitors. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  16. Finding All Solutions to the Magic Hexagram

    ERIC Educational Resources Information Center

    Holland, Jason; Karabegov, Alexander

    2008-01-01

    In this article, a systematic approach is given for solving a magic star puzzle that usually is accomplished by trial and error or "brute force." A connection is made to the symmetries of a cube, thus the name Magic Hexahedron.

  17. MAGIC Computer Simulation. Volume 1: User Manual

    DTIC Science & Technology

    1970-07-01

    vulnerability and MAGIC programs. A three-digit code is assigned to each component of the target, such as armor, gun tube; and a two-digit code is assigned to...A review of the subject Magic Computer Simulation User and Analyst Manuals has been conducted based upon a request received from the US Army...1970 4. TITLE AND SUBTITLE MAGIC Computer Simulation 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT

  18. An Overview of the MAGIC Project

    DTIC Science & Technology

    1993-12-01

    unlimnitedj_ _______ 13. ABSTRACT (Mxmwn WO0 words) This note provides an overview of the MAGIC project1 which is developing a high-speed, wide-area...298Rv.9 16. PRICE COASSDE 3.1 17. SEURITY18. SEURITY19. SEURITY2930.2BIA NO An Overview of the M 93B0000173 MAGIC Project December 1993 Barbara B...Intelligence Division ii ABSTRACT This note provides an overview of the MAGIC project, which is developing a high-speed, wide- area networking testbed

  19. Secrets of the Chinese magic mirror replica

    NASA Astrophysics Data System (ADS)

    Mak, Se-yuen; Yip, Din-yan

    2001-03-01

    We examine the structure of five Chinese magic mirror replicas using a special imaging technique developed by the authors. All mirrors are found to have a two-layered structure. The reflecting surface that gives rise to a projected magic pattern on the screen is hidden under a polished half-reflecting top layer. An alternative method of making the magic mirror using ancient technology has been proposed. Finally, we suggest a simple method of reconstructing a mirror replica in the laboratory.

  20. An fMRI investigation of expectation violation in magic tricks.

    PubMed

    Danek, Amory H; Öllinger, Michael; Fraps, Thomas; Grothe, Benedikt; Flanagin, Virginia L

    2015-01-01

    Magic tricks violate the expected causal relationships that form an implicit belief system about what is possible in the world around us. Observing a magic effect seemingly invalidates our implicit assumptions about what action causes which outcome. We aimed at identifying the neural correlates of such expectation violations by contrasting 24 video clips of magic tricks with 24 control clips in which the expected action-outcome relationship is upheld. Using fMRI, we measured the brain activity of 25 normal volunteers while they watched the clips in the scanner. Additionally, we measured the professional magician who had performed the magic tricks under the assumption that, in contrast to naïve observers, the magician himself would not perceive his own magic tricks as an expectation violation. As the main effect of magic - control clips in the normal sample, we found higher activity for magic in the head of the caudate nucleus (CN) bilaterally, the left inferior frontal gyrus and the left anterior insula. As expected, the magician's brain activity substantially differed from these results, with mainly parietal areas (supramarginal gyrus bilaterally) activated, supporting our hypothesis that he did not experience any expectation violation. These findings are in accordance with previous research that has implicated the head of the CN in processing changes in the contingency between action and outcome, even in the absence of reward or feedback.

  1. Magic in the machine: a computational magician's assistant.

    PubMed

    Williams, Howard; McOwan, Peter W

    2014-01-01

    A human magician blends science, psychology, and performance to create a magical effect. In this paper we explore what can be achieved when that human intelligence is replaced or assisted by machine intelligence. Magical effects are all in some form based on hidden mathematical, scientific, or psychological principles; often the parameters controlling these underpinning techniques are hard for a magician to blend to maximize the magical effect required. The complexity is often caused by interacting and often conflicting physical and psychological constraints that need to be optimally balanced. Normally this tuning is done by trial and error, combined with human intuitions. Here we focus on applying Artificial Intelligence methods to the creation and optimization of magic tricks exploiting mathematical principles. We use experimentally derived data about particular perceptual and cognitive features, combined with a model of the underlying mathematical process to provide a psychologically valid metric to allow optimization of magical impact. In the paper we introduce our optimization methodology and describe how it can be flexibly applied to a range of different types of mathematics based tricks. We also provide two case studies as exemplars of the methodology at work: a magical jigsaw, and a mind reading card trick effect. We evaluate each trick created through testing in laboratory and public performances, and further demonstrate the real world efficacy of our approach for professional performers through sales of the tricks in a reputable magic shop in London.

  2. Radiofrequency fields in MAS solid state NMR probes.

    PubMed

    Tošner, Zdeněk; Purea, Armin; Struppe, Jochem O; Wegner, Sebastian; Engelke, Frank; Glaser, Steffen J; Reif, Bernd

    2017-11-01

    We present a detailed analysis of the radiofrequency (RF) field over full volume of a rotor that is generated in a solenoid coil. On top of the usually considered static distribution of amplitudes along the coil axis we describe dynamic radial RF inhomogeneities induced by sample rotation. During magic angle spinning (MAS), the mechanical rotation of the sample about the magic angle, a spin packet travels through areas of different RF fields and experiences periodical modulations of both the RF amplitude and the phase. These modulations become particularly severe at the end regions of the coil where the relative RF amplitude varies up to ±25% and the RF phase changes within ±30°. Using extensive numerical simulations we demonstrate effects of RF inhomogeneity on pulse calibration and for the ramped CP experiment performed at a wide range of MAS rates. In addition, we review various methods to map RF fields using a B 0 gradient along the sample (rotor axis) for imaging purposes. Under such a gradient, a nutation experiment provides directly the RF amplitude distribution, a cross polarization experiment images the correlation of the RF fields on the two channels according to the Hartmann-Hahn matching condition, while a spin-lock experiment allows to calibrate the RF amplitude employing the rotary resonance recoupling condition. Knowledge of the RF field distribution in a coil provides key to understand its effects on performance of a pulse sequence at the spectrometer and enables to set robustness requirements in the experimental design. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Intensity-modulated polarizabilities and magic trapping of alkali-metal and divalent atoms in infrared optical lattices

    NASA Astrophysics Data System (ADS)

    Topcu, Turker; Derevianko, Andrei

    2014-05-01

    Long range interactions between neutral Rydberg atoms has emerged as a potential means for implementing quantum logical gates. These experiments utilize hyperfine manifold of ground state atoms to act as a qubit basis, while exploiting the Rydberg blockade mechanism to mediate conditional quantum logic. The necessity for overcoming several sources of decoherence makes magic wavelength trapping in optical lattices an indispensable tool for gate experiments. The common wisdom is that atoms in Rydberg states see trapping potentials that are essentially that of a free electron, and can only be trapped at laser intensity minima. We show that although the polarizability of a Rydberg state is always negative, the optical potential can be both attractive or repulsive at long wavelengths (up to ~104 nm). This opens up the possibility of magic trapping Rydberg states with ground state atoms in optical lattices, thereby eliminating the necessity to turn off trapping fields during gate operations. Because the wavelengths are near the CO2 laser band, the photon scattering and the ensuing motional heating is also reduced compared to conventional traps near low lying resonances, alleviating an important source of decoherence. This work was supported by the National Science Foundation (NSF) Grant No. PHY-1212482.

  4. A Simple Parameterization of 3 x 3 Magic Squares

    ERIC Educational Resources Information Center

    Trenkler, Gotz; Schmidt, Karsten; Trenkler, Dietrich

    2012-01-01

    In this article a new parameterization of magic squares of order three is presented. This parameterization permits an easy computation of their inverses, eigenvalues, eigenvectors and adjoints. Some attention is paid to the Luoshu, one of the oldest magic squares.

  5. Staging research of human lung cancer tissues by high-resolution magic angle spinning proton nuclear magnetic resonance spectroscopy (HRMAS 1 H NMR) and multivariate data analysis.

    PubMed

    Chen, Wenxue; Lu, Shaohua; Wang, Guifang; Chen, Fener; Bai, Chunxue

    2017-10-01

    High-resolution magic-angle spinning proton nuclear magnetic resonance (HRMAS 1 H NMR) spectroscopy technique was employed to analyze the metabonomic characterizations of lung cancer tissues in hope to identify potential diagnostic biomarkers for malignancy detection and staging research of lung tissues. HRMAS 1 H NMR spectroscopy technique can rapidly provide important information for accurate diagnosis and staging of cancer tissues owing to its noninvasive nature and limited requirement for the samples, and thus has been acknowledged as an excellent tool to investigate tissue metabolism and provide a more realistic insight into the metabonomics of tissues when combined with multivariate data analysis (MVDA) such as component analysis and orthogonal partial least squares-discriminant analysis in particular. HRMAS 1 H NMR spectra displayed the metabonomic differences of 32 lung cancer tissues at the different stages from 32 patients. The significant changes (P < 0.05) of some important metabolites such as lipids, aspartate and choline-containing compounds in cancer tissues at the different stages had been identified. Furthermore, the combination of HRMAS 1 H NMR spectroscopy and MVDA might potentially and precisely provided for a high sensitivity, specificity, prediction accuracy in the positive identification of the staging for the cancer tissues in contrast with the pathological data in clinic. This study highlighted the potential of metabonomics in clinical settings so that the techniques might be further exploited for the diagnosis and staging prediction of lung cancer in future. © 2016 John Wiley & Sons Australia, Ltd.

  6. Selective excitation enables assignment of proton resonances and (1)H-(1)H distance measurement in ultrafast magic angle spinning solid state NMR spectroscopy.

    PubMed

    Zhang, Rongchun; Ramamoorthy, Ayyalusamy

    2015-07-21

    Remarkable developments in ultrafast magic angle spinning (MAS) solid-state NMR spectroscopy enabled proton-based high-resolution multidimensional experiments on solids. To fully utilize the benefits rendered by proton-based ultrafast MAS experiments, assignment of (1)H resonances becomes absolutely necessary. Herein, we propose an approach to identify different proton peaks by using dipolar-coupled heteronuclei such as (13)C or (15)N. In this method, after the initial preparation of proton magnetization and cross-polarization to (13)C nuclei, transverse magnetization of desired (13)C nuclei is selectively prepared by using DANTE (Delays Alternating with Nutations for Tailored Excitation) sequence and then, it is transferred to bonded protons with a short-contact-time cross polarization. Our experimental results demonstrate that protons bonded to specific (13)C atoms can be identified and overlapping proton peaks can also be assigned. In contrast to the regular 2D HETCOR experiment, only a few 1D experiments are required for the complete assignment of peaks in the proton spectrum. Furthermore, the finite-pulse radio frequency driven recoupling sequence could be incorporated right after the selection of specific proton signals to monitor the intensity buildup for other proton signals. This enables the extraction of (1)H-(1)H distances between different pairs of protons. Therefore, we believe that the proposed method will greatly aid in fast assignment of peaks in proton spectra and will be useful in the development of proton-based multi-dimensional solid-state NMR experiments to study atomic-level resolution structure and dynamics of solids.

  7. Attentional Focus versus Diffuse Attention: Which is Better in Toddlers?

    ERIC Educational Resources Information Center

    Rivière, James; Cordonnier, Aurore; Fouasse, Christie

    2017-01-01

    How toddlers' attention is distributed in the visual field during a magic trick was examined using three expectation conditions. Results showed that 2.5-year-old children assigned to the condition with major task-relevant information (i.e., a verbal cue to attend to one of the visual targets) (i) outperformed those who were assigned to the…

  8. [Modern magic and medicine].

    PubMed

    Prokop, O

    1975-01-01

    In a paper presented on the occasion of the 5th Congress of gynecology in the GDR the author discusses in details the phenomenon of modern occultism and quackery. Preferably he examines the so called parapsychology and declares that this is a field without any scientific value. Therefore the course of action of parapsychologists is not to be accepted without resolute reply.

  9. Effect of science magic applied in interactive lecture demonstrations on conceptual understanding

    NASA Astrophysics Data System (ADS)

    Taufiq, Muhammad; Suhandi, Andi; Liliawati, Winny

    2017-08-01

    Research about the application of science magic-assisting Interactive Lecture Demonstrations (ILD) has been conducted. This research is aimed at providing description about the comparison of the improvement of the conceptual understanding of lesson on pressure between students who receive physics lesson through science magic-assisting ILD and students who receive physics lesson through ILD without science magic. This research used a quasi-experiment methods with Control Group Pretest-Posttest Design. The subject of the research is all students of class VIII in one of MTs (Islamic junior high school) in Pekalongan. Research samples were selected using random sampling technique. Data about students' conceptual understanding was collected using test instrument of conceptual understanding in the form of multiple choices. N-gain average calculation was performed in order to determine the improvement of students' conceptual understanding. The result of the research shows that conceptual understanding of students on lesson about pressure who received lesson with ILD using science magic <0.44> is higher than students who received lesson with ILD without science magic <0.25>. Therefore, the conclusion is that the application of science magic ILD is more effective to improve the conceptual understanding of lesson on pressure.

  10. The role of magical thinking in hallucinations. Comparisons of clinical and non-clinical groups.

    PubMed

    García-Montes, José M; Pérez-Álvarez, Marino; Odriozola-González, Paula; Vallina-Fernández, Oscar; Perona-Garcelán, Salvador

    2014-11-01

    Magical thinking consists of accepting the possibility that events that, according to the causal concepts of a culture, cannot have any causal relationship, but might somehow nevertheless have one. Magical thinking has been related to both obsessive-compulsive disorder and schizophrenia. The purpose of this study was to investigate the role of magical thinking in hallucinations of patients diagnosed with schizophrenia. Four groups were recruited for this purpose from a clinical population (hallucinating schizophrenic patients, patients diagnosed with psychoses who had never hallucinated, obsessive-compulsive disorder patients and a clinical control group) and a non-clinical control group, who were given the Magical Ideation Scale. The results show that magical ideation differentiates the group of schizophrenic patients with auditory hallucinations from the rest of the groups that participated in the design. Items related to "mind reading", to the presence of auditory illusions in response to sound stimuli, and to the sense of sometimes being accompanied by an evil presence are the most closely related to the presence of auditory hallucinations. Magical thinking, understood as beliefs in non-consensual modes of causation, is closely linked to auditory hallucinations in patients diagnosed with schizophrenia.

  11. Holographic Rovers: Augmented Reality and the Microsoft HoloLens

    NASA Technical Reports Server (NTRS)

    Toler, Laura

    2017-01-01

    Augmented Reality is an emerging field in technology, and encompasses Head Mounted Displays, smartphone apps, and even projected images. HMDs include the Meta 2, Magic Leap, Avegant Light Field, and the Microsoft HoloLens, which is evaluated specifically. The Microsoft HoloLens is designed to be used as an AR personal computer, and is being optimized with that goal in mind. Microsoft allied with the Unity3D game engine to create an SDK for interested application developers that can be used in the Unity environment.

  12. Influence of the position of the foot on MRI signal in the deep digital flexor tendon and collateral ligaments of the distal interphalangeal joint in the standing horse.

    PubMed

    Spriet, M; Zwingenberger, A

    2009-05-01

    Hyperintense signal is sometimes observed in ligaments and tendons of the equine foot on standing magnetic resonance examination without associated changes in size and shape. In such cases, the presence of a true lesion or an artifact should be considered. A change in position of a ligament or tendon relative to the magnetic field can induce increased signal intensity due to the magic angle effect. To assess if positional rotation of the foot in the solar plane could be responsible for artifactual changes in signal intensity in the collateral ligaments of the distal interphalangeal joint and in the deep digital flexor tendon. Six isolated equine feet were imaged with a standing equine magnetic resonance system in 9 different positions with different degrees of rotation in the solar plane. Rotation of the limb induced a linear hyperintense signal on all feet at the palmar aspect of one of the lobes of the deep digital flexor tendon and at the dorsal aspect of the other lobe. Changes in signal intensity in the collateral ligaments of the distal interphalangeal joint occurred with rotation of the limb only in those feet where mediolateral hoof imbalance was present. The position and conformation of the foot influence the signal intensity in the deep digital flexor tendon and in the collateral ligaments of the distal interphalangeal joint. The significance of increased signal intensity in the deep digital flexor tendon and in the collateral ligaments of the distal interphalangeal joint should be interpreted with regard to the position and the conformation of the foot.

  13. Early Childhood Corner: Take the Magic Out of Your Classroom!

    ERIC Educational Resources Information Center

    Andrews, Angela Giglio

    1995-01-01

    Students are often as mystified by mathematical procedures as they are by magic tricks. This article suggests ways of making the estimation of how many jelly beans in a jar and the 20-questions game less magical and more understandable. (MKR)

  14. Magical thinking by inpatient staff members.

    PubMed

    Pilette, W L

    1983-01-01

    Magical thinking is a primitive form of mental activity which, nevertheless, the author contends, is common among mental health professionals. Four examples of magical thinking by inpatient staff members are presented and briefly explored, in order to shed light on our work and ourselves.

  15. [Further Distinctions between Magic, Reality, Religion, and Fiction. Commentaries.

    ERIC Educational Resources Information Center

    Boyer, Pascal; Taylor, Marjorie; Harris, Paul L.; Chandler, Michael; Johnson, Carl N.

    1997-01-01

    Contains the following commentaries: "Further Distinctions between Magic, Reality, Religion, and Fiction"; "The Role of Creative Control and Culture in Children's Fantasy/Reality Judgments"; "The Last of the Magicians? Children, Scientists, and the Invocation of Hidden Causal Powers"; "Rescuing Magical Thinking…

  16. The Magic Background of Pearl Harbor. Volume 1 (February 14, 1941 - May 12, 1941)

    DTIC Science & Technology

    1977-01-01

    1977 2. REPORT TYPE 3. DATES COVERED 00-00-1977 to 00-00-1977 4. TITLE AND SUBTITLE The ’ Magic ’ Background of Pearl Harbor. Volume 1: February...34 MAGIC " BACKGROUND OF PEARL HARBOR VOLUME I (February 14, 1941-May 12,1941) /- / DEPARTMENT OF DEFENSE UNITED STATES OF AMERICA For sale by the...The Department of Defense is releasing for public use and research this multi-volume study giving the " MAGIC " or communications intelligence background

  17. Further Studies of the NRL Collective Particle Accelerator VIA Numerical Modeling with the MAGIC Code.

    DTIC Science & Technology

    1984-08-01

    COLLFCTIVF PAPTTCLE ACCELERATOR VIA NUMERICAL MODFLINC WITH THF MAGIC CODE Robert 1. Darker Auqust 19F4 Final Report for Period I April. qI84 - 30...NUMERICAL MODELING WITH THE MAGIC CODE Robert 3. Barker August 1984 Final Report for Period 1 April 1984 - 30 September 1984 Prepared for: Scientific...Collective Final Report Particle Accelerator VIA Numerical Modeling with April 1 - September-30, 1984 MAGIC Code. 6. PERFORMING ORG. REPORT NUMBER MRC/WDC-R

  18. [Magical thinking and self development].

    PubMed

    Resch, F

    1994-01-01

    Based on a historical survey of the term "magic thinking" structural aspects of primary process and prelogical thinking will be elucidated. Developmental necessities for the emergence of magic interpretations in children of pre-school age are proposed. The thesis will be formulated, that magic interpretations may help the developing self in the management of life-circumstances during a period of cognitive egocentrism: feelings of non-competence may be compensated, and the locus of control may be held in the face of experiences of inferiority.

  19. [The magic universe of cures: the role of magic practices and witchcraft in the universe of 17th century Mato Grosso].

    PubMed

    Sá, Mario

    2009-01-01

    The article analyzes the role of healing agents played by practitioners of magic and witchcraft in Mato Grosso society during the 17th century. It observes that magic and witchcraft were developed as competitors, alternatives or associated with other forms of healing (official and lay). It points out how such roles contributed to the process of subjugating its practitioners, especially Africans, Indians and their descendents, and were appropriated as an opportunity for survival in the colonial slave society. The pastoral visit made by Bruno Pinna in 1785 to Cuiabá and nearby areas served as the principal source of knowledge regarding the practices and practitioners of magic and witchcraft.

  20. Ka-Band TWT High-Efficiency Power Combiner for High-Rate Data Transmission

    NASA Technical Reports Server (NTRS)

    Wintucky, Edwin G.; Simons, Rainee; Vaden, Karl R.; Lesny, Gary G.; Glass, Jeffrey L.

    2007-01-01

    A four-port magic-T hybrid waveguide junction serves as the central component of a high-efficiency two-way power combiner circuit for transmitting a high-rate phase-modulated digital signal at a carrier frequency in the Ka-band (between 27 and 40 GHz). This power combiner was developed to satisfy a specific requirement to efficiently combine the coherent outputs of two traveling-wavetube (TWT) amplifiers that are typically characterized by power levels on the order of 100 W or more. In this application, the use of a waveguide-based power combiner (instead of a coaxial-cable- or microstrip-based power combiner, for example) is dictated by requirements for low loss, high power-handling capability, and broadband response. Combiner efficiencies were typically 90 percent or more over both the linear and saturated output power regions of operation of the TWTs . Figure 1 depicts the basic configuration of the magic-T hybrid junction. The coherent outputs of the two TWTs enter through ports 1 and 4. As a result of the orientations of the electromagnetic fields, which also provides a needed high port-to-port isolation, of these two input signals and the interior design of the magic-T junction, the input powers are divided so as to add in phase at one output port (port 2), and to be opposite in phase and hence cancel each other at the opposite coplanar output port (port 3). The net result is that the output power at port 2 is essentially double that of the output of one TWT, minus the power lost in the magic-T hybrid junction. Optimum performance as a high-efficiency power combiner thus requires a balance of both power and phase at the input ports of the magic-T. Replicas of this two-way combiner can be arranged in a binary configuration to obtain a 2n-way (where n is an integer) combiner. For example, Figure 2 illustrates the use of three two-way combiners to combine the outputs of four TWTs.

  1. When "Holiday Magic" Hurts.

    ERIC Educational Resources Information Center

    Goldstein, Karen

    2001-01-01

    Claims that religious messages in public school are not acceptable and are hurtful to kids who do not subscribe to the beliefs expressed in those messages. Describes the author's personal experience in helping a teacher transform the script for "Christmas Magic" into the more inclusive "Holiday Magic." (RS)

  2. [Investigation into the formation of proportions of "realistic thinking vs magical thinking" in paranoid schizophrenia].

    PubMed

    Jarosz, M; Pankiewicz, Z; Buczek, I; Poprawska, I; Rojek, J; Zaborowski, A

    1993-01-01

    Both magical thinking among healthy persons and magical and symbolic thinking in schizophrenia were discussed. The investigation covered 100 paranoid schizophrenics. They also underwent an examination in connection with the formation of the remaining 3 proportions. Both "realistic thinking and magical thinking" scales were used. An ability to think realistically was preserved, to a varying degree, in all patients, with 50% of those examined having shown an explicit or very explicit ability to follow realistic thinking. The above findings deviate from a simplified cognitive model within the discussed range. It was further confirmed that realistic thinking may coexist with magical thinking, and, in some cases, it concerns the same events. That type of disorders of the content of thinking are referred to as magical-realistic interpenetration. The results, and particularly high coefficient of negative correlation within the scales of the examined proportions, confirm the correctness of the assumption that the investigated modes of thinking form an antithetic bipolarity of proportions, aggregating antithetic values, therefore being also complementary.

  3. Magical attachment: Children in magical relations with hospital clowns

    PubMed Central

    2012-01-01

    The aim of the present study was to achieve a theoretical understanding of several different-age children's experiences of magic relations with hospital clowns in the context of medical care, and to do so using psychological theory and a child perspective. The method used was qualitative and focused on nine children. The results showed that age was important to consider in better understanding how the children experienced the relation with the hospital clowns, how they described the magical aspects of the encounter and how they viewed the importance of clown encounters to their own well-being. The present theoretical interpretation characterized the encounter with hospital clowns as a magical safe area, an intermediate area between fantasy and reality. The discussion presented a line of reasoning concerning a magical attachment between the child and the hospital clowns, stating that this attachment: a) comprised a temporary relation; b) gave anonymity; c) entailed reversed roles; and d) created an emotional experience of boundary-transcending opportunities. PMID:22371813

  4. The presence of magical thinking in obsessive compulsive disorder.

    PubMed

    Einstein, Danielle A; Menzies, Ross G

    2004-05-01

    Two research groups have raised the possibility that magical ideation may be a fundamental feature of obsessive-compulsive disorder. It has been proposed to underlie thought action fusion and superstitious beliefs. In this study, the Magical Ideation scale, the Lucky Behaviours and Lucky Beliefs scales, the Thought Action Fusion-Revised scale, the Padua Inventory, and the Obsessive Compulsive Inventory-Short Version were completed by 60 obsessive compulsive patients at a hospital clinic. Of all the measures, the Magical Ideation (MI) scale was found to be the most strongly related to obsessive compulsive symptoms. Large and significant relationships between MI scores and the measures of OCD were obtained even when alternative constructs (Lucky Behaviours, Lucky Beliefs, Thought Action Fusion-Revised scales) were held constant. No other variable remained significantly related to the Obsessive Compulsive Inventory-Short Version when magical ideation scores were held constant. The findings suggest that a general magical thinking tendency may underpin previous observed links between superstitiousness, thought action fusion and OCD severity.

  5. 13C Nuclear magnetic resonance studies of kerogen from Cretaceous black shales thermally altered by basaltic intrusions and laboratory simulations

    USGS Publications Warehouse

    Dennis, L.W.; Maciel, G.E.; Hatcher, P.G.; Simoneit, B.R.T.

    1982-01-01

    Cretaceous black shales from DSDP Leg 41, Site 368 in the Eastern Atlantic Ocean were thermally altered during the Miocene by an intrusive basalt. The sediments overlying and underlying the intrusive body were subjected to high temperatures (up to ~ 500??C) and, as a result, their kerogen was significantly altered. The extent of this alteration has been determined by examination by means of 13C nuclear magnetic resonance, using cross polarization/magic-angle spinning (CP/MAS). Results indicate that the kerogen becomes progressively more aromatic in the vicinity of the intrusive body. Laboratory heating experiments, simulating the thermal effects of the basaltic intrusion, produced similar results on unaltered shale from the drill core. The 13C CP/MAS results appear to provide a good measure of thermal alteration. ?? 1982.

  6. Magic in the machine: a computational magician's assistant

    PubMed Central

    Williams, Howard; McOwan, Peter W.

    2014-01-01

    A human magician blends science, psychology, and performance to create a magical effect. In this paper we explore what can be achieved when that human intelligence is replaced or assisted by machine intelligence. Magical effects are all in some form based on hidden mathematical, scientific, or psychological principles; often the parameters controlling these underpinning techniques are hard for a magician to blend to maximize the magical effect required. The complexity is often caused by interacting and often conflicting physical and psychological constraints that need to be optimally balanced. Normally this tuning is done by trial and error, combined with human intuitions. Here we focus on applying Artificial Intelligence methods to the creation and optimization of magic tricks exploiting mathematical principles. We use experimentally derived data about particular perceptual and cognitive features, combined with a model of the underlying mathematical process to provide a psychologically valid metric to allow optimization of magical impact. In the paper we introduce our optimization methodology and describe how it can be flexibly applied to a range of different types of mathematics based tricks. We also provide two case studies as exemplars of the methodology at work: a magical jigsaw, and a mind reading card trick effect. We evaluate each trick created through testing in laboratory and public performances, and further demonstrate the real world efficacy of our approach for professional performers through sales of the tricks in a reputable magic shop in London. PMID:25452736

  7. Nano-Mole Scale Side-Chain Signal Assignment by 1H-Detected Protein Solid-State NMR by Ultra-Fast Magic-Angle Spinning and Stereo-Array Isotope Labeling

    PubMed Central

    Nishiyama, Yusuke; Endo, Yuki; Nemoto, Takahiro; Yamauchi, Kazuo; Asakura, Tetsuo; Takeda, Mitsuhiro; Terauchi, Tsutomu; Kainosho, Masatsune; Ishii, Yoshitaka

    2015-01-01

    We present a general approach in 1H-detected 13C solid-state NMR (SSNMR) for side-chain signal assignments of 10-50 nmol quantities of proteins using a combination of a high magnetic field, ultra-fast magic-angle spinning (MAS) at ~80 kHz, and stereo-array-isotope-labeled (SAIL) proteins [Kainosho M. et al., Nature 440, 52–57, 2006]. First, we demonstrate that 1H indirect detection improves the sensitivity and resolution of 13C SSNMR of SAIL proteins for side-chain assignments in the ultra-fast MAS condition. 1H-detected SSNMR was performed for micro-crystalline ubiquitin (~55 nmol or ~0.5mg) that was SAIL-labeled at seven isoleucine (Ile) residues. Sensitivity was dramatically improved by 1H-detected 2D 1H/13C SSNMR by factors of 5.4-9.7 and 2.1-5.0, respectively, over 13C-detected 2D 1H/13C SSNMR and 1D 13C CPMAS, demonstrating that 2D 1H-detected SSNMR offers not only additional resolution but also sensitivity advantage over 1D 13C detection for the first time. High 1H resolution for the SAIL-labeled side-chain residues offered reasonable resolution even in the 2D data. A 1H-detected 3D 13C/13C/1H experiment on SAIL-ubiquitin provided nearly complete 1H and 13C assignments for seven Ile residues only within ~2.5 h. The results demonstrate the feasibility of side-chain signal assignment in this approach for as little as 10 nmol of a protein sample within ~3 days. The approach is likely applicable to a variety of proteins of biological interest without any requirements of highly efficient protein expression systems. PMID:25856081

  8. First NuSTAR Observations of Mrk 501 within a Radio to TeV Multi-Instrument Campaign

    DOE PAGES

    Furniss, Amy

    2015-10-08

    We report on simultaneous broadband observations of the TeV-emitting blazar Markarian 501 between 2013 April 1 and August 10, including the first detailed characterization of the synchrotron peak with Swift and NuSTAR. During the campaign, the nearby BL Lac object was observed in both a quiescent and an elevated state. The broadband campaign includes observations with NuSTAR, MAGIC, VERITAS, the Fermi Large Area Telescope, Swift X-ray Telescope and UV Optical Telescope, various ground-based optical instruments, including the GASP-WEBT program, as well as radio observations by OVRO, Metsähovi, and the F-Gamma consortium. Some of the MAGIC observations were affected by amore » sand layer from the Saharan desert, and had to be corrected using event-by-event corrections derived with a Light Detection and Ranging (LIDAR) facility. This is the first time that LIDAR information is used to produce a physics result with Cherenkov Telescope data taken during adverse atmospheric conditions, and hence sets a precedent for the current and future ground-based gamma-ray instruments. The NuSTAR instrument provides unprecedented sensitivity in hard X-rays, showing the source to display a spectral energy distribution (SED) between 3 and 79 keV consistent with a log-parabolic spectrum and hard X-ray variability on hour timescales. None (of the four extended NuSTAR observations) show evidence of the onset of inverse-Compton emission at hard X-ray energies. We apply a single-zone equilibrium synchrotron self-Compton (SSC) model to five simultaneous broadband SEDs. We find that the SSC model can reproduce the observed broadband states through a decrease in the magnetic field strength coinciding with an increase in the luminosity and hardness of the relativistic leptons responsible for the high-energy emission.« less

  9. Enceladus Environmental Explorer (EVE): A Mission Concept

    NASA Astrophysics Data System (ADS)

    Lawson, M. J.; Amador, E. S.; Carrier, B. L.; Albuja, A.; Bapst, J.; Cahill, K. R. S.; Ebersohn, F.; Gainey, S.; Gartrelle, G.; Greenberger, R. N.; Hale, J. M.; Johnston, S.; Olivares, J.; Parcheta, C. E.; Sheehan, J. P.; Thorpe, A. K.; Zareh, S. K.

    2014-12-01

    Enceladus is an intriguing planetary body, which possibly has the ingredients needed for life. Further, it has numerous (over 100) continuously erupting geysers that eject material into the atmosphere which provide a unique opportunity to sample the body's internal chemistry from orbit. At JPL's Planetary Science Summer School, Team X and a group of students developed a mission concept to directly sample Enceladus' plumes. The mission, named Enceladus Environmental Explorer (EVE), follows NASA's Planetary Science Decadal survey and would assess the potential habitability of Saturn's icy satellite through analysis of the chemistry of the subsurface ocean and the nature of the organic chemistry in the plume. EVE would look at geological and geophysical surface processes of Enceladus by investigating the heat output of Enceladus, plumes' mechanics, the extent of the liquid subsurface reservoir(s), and gravitational variation. The EVE mission concept aimed for a January 2023 launch on an Atlas 551 class launch vehicle and would arrive at Saturn July 2031. A two-year-long Saturn moon tour would allow sufficient deceleration to permit a polar orbital insertion around Enceladus in March 2035, remaining stable for 54 weeks of observation. The proposed instrument payload includes: 1) SUb MilliMeter Enceladus Radiometer (SUMMER; equivalent to Rosetta MIRO), 2) Enceladus Dust and Gas Experiment (EDGE; an enhanced version of Rosetta COSIMA), 3) MAGnetometer for Ionic Concentration (MAGIC; equivalent to MMS/ InSIGHT magnetometer), 4) Visual Imaging Camera with Topographic Observational Resolution (VICTOR) and 5) Enceladus Radio Gravity Science (ERGS). Our suggested orbital timeline would allow the most comprehensive dataset yet collected of a moon in the outer solar system, mapping the entire surface twice with SUMMER and VICTOR, while sampling the plume directly 232 times with EDGE. MAGIC would also provide over a year of sampling of the magnetic field variations from orbit. Enceladus Environmental Explorer (EVE) offers a unique opportunity to determine the potential for life on Enceladus.

  10. FIRST NuSTAR OBSERVATIONS OF MRK 501 WITHIN A RADIO TO TeV MULTI-INSTRUMENT CAMPAIGN

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Furniss, A.; Noda, K.; Boggs, S.

    2015-10-10

    We report on simultaneous broadband observations of the TeV-emitting blazar Markarian 501 between 2013 April 1 and August 10, including the first detailed characterization of the synchrotron peak with Swift and NuSTAR. During the campaign, the nearby BL Lac object was observed in both a quiescent and an elevated state. The broadband campaign includes observations with NuSTAR, MAGIC, VERITAS, the Fermi Large Area Telescope, Swift X-ray Telescope and UV Optical Telescope, various ground-based optical instruments, including the GASP-WEBT program, as well as radio observations by OVRO, Metsähovi, and the F-Gamma consortium. Some of the MAGIC observations were affected by amore » sand layer from the Saharan desert, and had to be corrected using event-by-event corrections derived with a Light Detection and Ranging (LIDAR) facility. This is the first time that LIDAR information is used to produce a physics result with Cherenkov Telescope data taken during adverse atmospheric conditions, and hence sets a precedent for the current and future ground-based gamma-ray instruments. The NuSTAR instrument provides unprecedented sensitivity in hard X-rays, showing the source to display a spectral energy distribution (SED) between 3 and 79 keV consistent with a log-parabolic spectrum and hard X-ray variability on hour timescales. None (of the four extended NuSTAR observations) show evidence of the onset of inverse-Compton emission at hard X-ray energies. We apply a single-zone equilibrium synchrotron self-Compton (SSC) model to five simultaneous broadband SEDs. We find that the SSC model can reproduce the observed broadband states through a decrease in the magnetic field strength coinciding with an increase in the luminosity and hardness of the relativistic leptons responsible for the high-energy emission.« less

  11. Chinese "Magic" Mirrors.

    ERIC Educational Resources Information Center

    Swinson, Derek B.

    1992-01-01

    Chinese "magic" mirrors are made from bronze with the front side a mirror and the reverse side a molded image. When light is reflected from the mirror,the image on the reverse side appears. Discusses reflections of conventional mirrors, possible explanations for the magic mirror phenomenon, and applications of the phenomenon to…

  12. U.S. EPA, Pesticide Product Label, FLEAGO THE MAGIC CRYSTAL, 07/09/1997

    EPA Pesticide Factsheets

    2011-04-21

    ... Fleago The Magic Crystal '~~~:ul~~i~;~i~~!;~i~~fat~~I~~n~w~~~~: W~?~:~iA~~~~~r~Y '~~;: ... lhe Magic Crystal ...

  13. Efficiency of water-soluble nitroxide biradicals for dynamic nuclear polarization in rotating solids at 9.4 T: bcTol-M and cyolyl-TOTAPOL as new polarizing agents.

    PubMed

    Geiger, Michel; Jagtap, Anil; Kaushik, Monu; Sun, Han; Stöppler, Daniel; Sigurdsson, Snorri; Corzilius, Björn; Oschkinat, Hartmut

    2018-05-09

    Nitroxide biradicals are very efficient polarizing agents in magic angle spinning (MAS) cross effect (CE) dynamic nuclear polarization (DNP) nuclear magnetic resonance (NMR). Many recently synthesized, new radicals show superior DNP-efficiency in organic solvents but suffer from insufficient solubility in water or glycerol/water for biological applications. We report DNP efficiencies for two new radicals, the particularly well-water soluble bcTol-M and cyolyl-TOTAPOL, and include a comparison with three known biradicals, TOTAPOL, bcTol, and AMUPol. They differ by linker groups, featuring either a 3-aminopropane-1,2-diol or a urea tether, or by the structure of the alkyl substituents that flank the nitroxide groups. For evaluating their performances, we measured both signal enhancements  and DNP-enhanced sensitivity κ, and compared the results to electron spin relaxation data recorded at the same magnetic field strength (9.4 T). In our study, differences in DNP efficiency correlate with changes in the nuclear polarization dynamics rather than electron relaxation. The ratios of their individual ε and κ differ by up to 20%, which is explained by starkly different nuclear polarization build-up rates. For the radicals compared here empirically, using proline standard solutions, the new radical bcTol-M performs best while being most soluble in water/glycerol mixtures. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Frequency-agile gyrotron for electron decoupling and pulsed dynamic nuclear polarization.

    PubMed

    Scott, Faith J; Saliba, Edward P; Albert, Brice J; Alaniva, Nicholas; Sesti, Erika L; Gao, Chukun; Golota, Natalie C; Choi, Eric J; Jagtap, Anil P; Wittmann, Johannes J; Eckardt, Michael; Harneit, Wolfgang; Corzilius, Björn; Th Sigurdsson, Snorri; Barnes, Alexander B

    2018-04-01

    We describe a frequency-agile gyrotron which can generate frequency-chirped microwave pulses. An arbitrary waveform generator (AWG) within the NMR spectrometer controls the microwave frequency, enabling synchronized pulsed control of both electron and nuclear spins. We demonstrate that the acceleration of emitted electrons, and thus the microwave frequency, can be quickly changed by varying the anode voltage. This strategy results in much faster frequency response than can be achieved by changing the potential of the electron emitter, and does not require a custom triode electron gun. The gyrotron frequency can be swept with a rate of 20 MHz/μs over a 670 MHz bandwidth in a static magnetic field. We have already implemented time-domain electron decoupling with dynamic nuclear polarization (DNP) magic angle spinning (MAS) with this device. In this contribution, we show frequency-swept DNP enhancement profiles recorded without changing the NMR magnet or probe. The profile of endofullerenes exhibits a DNP profile with a <10 MHz linewidth, indicating that the device also has sufficient frequency stability, and therefore phase stability, to implement pulsed DNP mechanisms such as the frequency-swept solid effect. We describe schematics of the mechanical and vacuum construction of the device which includes a novel flanged sapphire window assembly. Finally, we discuss how commercially available continuous-wave gyrotrons can potentially be converted into similar frequency-agile high-power microwave sources. Copyright © 2018. Published by Elsevier Inc.

  15. Indirect searches of Galactic diffuse dark matter in INO-MagICAL detector

    DOE PAGES

    Khatun, Amina; Laha, Ranjan; Agarwalla, Sanjib Kumar

    2017-06-12

    Here, the signatures for the existence of dark matter are revealed only through its gravitational interaction. Theoretical arguments support that the Weakly Interacting Massive Particle (WIMP) can be a class of dark matter and it can annihilate and/or decay to Standard Model particles, among which neutrino is a favorable candidate. We show that the proposed 50 kt Magnetized Iron CALorimeter (MagICAL) detector under the India-based Neutrino Observatory (INO) project can play an important role in the indirect searches of Galactic diffuse dark matter in the neutrino and antineutrino mode separately. We present the sensitivity of 500 kt·yr MagICAL detector to set limits on the velocity-averaged self-annihilation cross-section (more » $$\\langle$$σv$$\\rangle$$) and decay lifetime (τ) of dark matter having mass in the range of 2 GeV ≤ m χ ≤ 90 GeV and 4 GeV ≤ m χ ≤ 180 GeV respectively, assuming no excess over the conventional atmospheric neutrino and antineutrino fluxes at the INO site. Our limits for low mass dark matter constrain the parameter space which has not been explored before. We show that MagICAL will be able to set competitive constraints, $$\\langle$$σv$$\\rangle$$ ≤ 1.87 × 10 -24 cm 3 s -1 for χχ→$$ν\\overline{v}$$ χχ→$$ν\\overline{v}$$ and τ ≥ 4.8 × 10 24s for χ → $$ν\\overline{v}$$ χ → $$ν\\overline{v}$$ at 90% C.L. (1 d.o.f.) for m χ = 10 GeV assuming the NFW as dark matter density profile.« less

  16. Indirect searches of Galactic diffuse dark matter in INO-MagICAL detector

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Khatun, Amina; Laha, Ranjan; Agarwalla, Sanjib Kumar

    Here, the signatures for the existence of dark matter are revealed only through its gravitational interaction. Theoretical arguments support that the Weakly Interacting Massive Particle (WIMP) can be a class of dark matter and it can annihilate and/or decay to Standard Model particles, among which neutrino is a favorable candidate. We show that the proposed 50 kt Magnetized Iron CALorimeter (MagICAL) detector under the India-based Neutrino Observatory (INO) project can play an important role in the indirect searches of Galactic diffuse dark matter in the neutrino and antineutrino mode separately. We present the sensitivity of 500 kt·yr MagICAL detector to set limits on the velocity-averaged self-annihilation cross-section (more » $$\\langle$$σv$$\\rangle$$) and decay lifetime (τ) of dark matter having mass in the range of 2 GeV ≤ m χ ≤ 90 GeV and 4 GeV ≤ m χ ≤ 180 GeV respectively, assuming no excess over the conventional atmospheric neutrino and antineutrino fluxes at the INO site. Our limits for low mass dark matter constrain the parameter space which has not been explored before. We show that MagICAL will be able to set competitive constraints, $$\\langle$$σv$$\\rangle$$ ≤ 1.87 × 10 -24 cm 3 s -1 for χχ→$$ν\\overline{v}$$ χχ→$$ν\\overline{v}$$ and τ ≥ 4.8 × 10 24s for χ → $$ν\\overline{v}$$ χ → $$ν\\overline{v}$$ at 90% C.L. (1 d.o.f.) for m χ = 10 GeV assuming the NFW as dark matter density profile.« less

  17. Metabolic profiling of lung granuloma in Mycobacterium tuberculosis infected guinea pigs: ex vivo 1H magic angle spinning NMR studies.

    PubMed

    Somashekar, B S; Amin, Anita G; Rithner, Christopher D; Troudt, JoLynn; Basaraba, Randall; Izzo, Angelo; Crick, Dean C; Chatterjee, Delphi

    2011-09-02

    A crucial and distinctive feature of tuberculosis infection is that Mycobacterium tuberculosis (Mtb) resides in granulomatous lesion at various stages of disease development and necrosis, an aspect that is little understood. We used a novel approach, applying high resolution magic angle spinning nuclear magnetic resonance spectroscopy (HRMAS NMR) directly to infected tissues, allowing us to study the development of tuberculosis granulomas in guinea pigs in an untargeted manner. Significant up-regulation of lactate, alanine, acetate, glutamate, oxidized and the reduced form of glutathione, aspartate, creatine, phosphocholine, glycerophosphocholine, betaine, trimethylamine N-oxide, myo-inositol, scyllo-inositol, and dihydroxyacetone was clearly visualized and was identified as the infection progressed. Concomitantly, phosphatidylcholine was down-regulated. Principal component analysis of NMR data revealed clear group separation between infected and uninfected tissues. These metabolites are suggestive of utilization of alternate energy sources by the infiltrating cells that generate much of the metabolites in the increasingly necrotic and hypoxic developing granuloma through the glycolytic, pentose phosphate, and tricarboxylic acid pathways. The most relevant changes seen are, surprisingly, very similar to metabolic changes seen in cancer during tumor development.

  18. An MRI Scan of the nucleus

    NASA Astrophysics Data System (ADS)

    Hoffman, Calem

    2017-09-01

    In the pursuit of a global description of nuclei, extensive experimental studies on short-lived isotopes have provided a wealth of new empirical information. Such data has been used to test theoretical concepts and in the development of innovative ideas. More directly, a novel device at Argonne National Laboratory, the HELIcal Orbit Spectrometer (HELIOS), was focused on providing detailed single-particle information on the malleability of the nuclear magic numbers. Once thought as immovable pillars in nuclear structure, the shell-gaps in nuclei defining magic numbers of nucleons are now well-known to evolve as proton-to-neutron ratios change. And, determination of the underlying components of the nuclear force driving the evolution is at the forefront of nuclear structure research. Additionally, the HELIOS device mentioned above also carries its own aura being that it is formed by a decommissioned MRI solenoid magnet. In this talk recent highlights and advancements in our description of nuclear shell evolution will be the focus along with a few sidestepping comments on the life-cycle and interplay between basic research and the applications of nuclear physics. This material is based upon work supported by the U.S. Department of Energy, Office of Science, under Contract Number DE-AC02-06CH11357.

  19. Structural Masquerade of Plesiomonas shigelloides Strain CNCTC 78/89 O-Antigen-High-Resolution Magic Angle Spinning NMR Reveals the Modified d-galactan I of Klebsiella pneumoniae.

    PubMed

    Ucieklak, Karolina; Koj, Sabina; Pawelczyk, Damian; Niedziela, Tomasz

    2017-11-29

    The high-resolution magic angle spinning nuclear magnetic resonance spectroscopy (HR-MAS NMR) analysis of Plesiomonas shigelloides 78/89 lipopolysaccharide directly on bacteria revealed the characteristic structural features of the O -acetylated polysaccharide in the NMR spectra. The O -antigen profiles were unique, yet the pattern of signals in the, spectra along with their ¹H, 13 C chemical shift values, resembled these of d-galactan I of Klebsiella pneumoniae . The isolated O- specific polysaccharide (O-PS) of P. shigelloides strain CNCTC 78/89 was investigated by ¹H and 13 C NMR spectroscopy, mass spectrometry and chemical methods. The analyses demonstrated that the P. shigelloides 78/89 O- PS is composed of →3)-α-d-Gal p -(1→3)-β-d-Gal f 2OAc-(1→ disaccharide repeating units. The O- acetylation was incomplete and resulted in a microheterogeneity of the O- antigen. This O- acetylation generates additional antigenic determinants within the O- antigen, forms a new chemotype, and contributes to the epitopes recognized by the O- serotype specific antibodies. The serological cross-reactivities further confirmed the inter-specific structural similarity of these O- antigens.

  20. Low-temperature dynamic nuclear polarization with helium-cooled samples and nitrogen-driven magic-angle spinning.

    PubMed

    Thurber, Kent; Tycko, Robert

    2016-03-01

    We describe novel instrumentation for low-temperature solid state nuclear magnetic resonance (NMR) with dynamic nuclear polarization (DNP) and magic-angle spinning (MAS), focusing on aspects of this instrumentation that have not been described in detail in previous publications. We characterize the performance of an extended interaction oscillator (EIO) microwave source, operating near 264 GHz with 1.5 W output power, which we use in conjunction with a quasi-optical microwave polarizing system and a MAS NMR probe that employs liquid helium for sample cooling and nitrogen gas for sample spinning. Enhancement factors for cross-polarized (13)C NMR signals in the 100-200 range are demonstrated with DNP at 25K. The dependences of signal amplitudes on sample temperature, as well as microwave power, polarization, and frequency, are presented. We show that sample temperatures below 30K can be achieved with helium consumption rates below 1.3 l/h. To illustrate potential applications of this instrumentation in structural studies of biochemical systems, we compare results from low-temperature DNP experiments on a calmodulin-binding peptide in its free and bound states. Published by Elsevier Inc.

  1. Simultaneous acquisition of 2D and 3D solid-state NMR experiments for sequential assignment of oriented membrane protein samples.

    PubMed

    Gopinath, T; Mote, Kaustubh R; Veglia, Gianluigi

    2015-05-01

    We present a new method called DAISY (Dual Acquisition orIented ssNMR spectroScopY) for the simultaneous acquisition of 2D and 3D oriented solid-state NMR experiments for membrane proteins reconstituted in mechanically or magnetically aligned lipid bilayers. DAISY utilizes dual acquisition of sine and cosine dipolar or chemical shift coherences and long living (15)N longitudinal polarization to obtain two multi-dimensional spectra, simultaneously. In these new experiments, the first acquisition gives the polarization inversion spin exchange at the magic angle (PISEMA) or heteronuclear correlation (HETCOR) spectra, the second acquisition gives PISEMA-mixing or HETCOR-mixing spectra, where the mixing element enables inter-residue correlations through (15)N-(15)N homonuclear polarization transfer. The analysis of the two 2D spectra (first and second acquisitions) enables one to distinguish (15)N-(15)N inter-residue correlations for sequential assignment of membrane proteins. DAISY can be implemented in 3D experiments that include the polarization inversion spin exchange at magic angle via I spin coherence (PISEMAI) sequence, as we show for the simultaneous acquisition of 3D PISEMAI-HETCOR and 3D PISEMAI-HETCOR-mixing experiments.

  2. Motivating students' participation in a computer networks course by means of magic, drama and games.

    PubMed

    Hilas, Constantinos S; Politis, Anastasios

    2014-01-01

    The recent economic crisis has forced many universities to cut down expenses by packing students into large lecture groups. The problem with large auditoria is that they discourage dialogue between students and faculty and they burden participation. Adding to this, students in computer science courses usually find the field to be full of theoretical and technical concepts. Lack of understanding leads them to lose interest and / or motivation. Classroom experience shows that the lecturer could employ alternative teaching methods, especially for early-year undergraduate students, in order to grasp their interest and introduce basic concepts. This paper describes some of the approaches that may be used to keep students interested and make them feel comfortable as they comprehend basic concepts in computer networks. The lecturing procedure was enriched with games, magic tricks and dramatic representations. This approach was used experimentally for two semesters and the results were more than encouraging.

  3. Shortwave Hyperspectral Observations During MAGIC Final Campaign Summary

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McBride, P. J.; Marshak, A.; Yang, W.

    The Marine ARM GPCI1 Investigation of Clouds (MAGIC) field campaign was initiated to improve our understanding of low-level marine clouds that have a significant influence on the Earth’s climate. The campaign was conducted using an ARM mobile facility deployed on a commercial ship traveling between Honolulu, Hawaii, and Los Angeles, California, from October 2012 to September 2013. The solar spectral flux radiometer (SSFR) was deployed on July 6, 2013, through the end of the campaign. The SSFR was calibrated and installed by Warren Gore of NASA Ames Research Center, and the data is and will be analyzed by Drs. Alexandermore » Marshak and Weidong Yang of NASA Goddard Space Flight Center, Dr. Samuel LeBlanc of NASA Ames Research Center, Dr. Sebastian Schmidt of the University of Colorado-Boulder, and Dr. Patrick McBride of Atmospheric & Space Technology Research Associates in Boulder, Colorado.« less

  4. Everyday magical powers: the role of apparent mental causation in the overestimation of personal influence.

    PubMed

    Pronin, Emily; Wegner, Daniel M; McCarthy, Kimberly; Rodriguez, Sylvia

    2006-08-01

    These studies examined whether having thoughts related to an event before it occurs leads people to infer that they caused the event--even when such causation might otherwise seem magical. In Study 1, people perceived that they had harmed another person via a voodoo hex. These perceptions were more likely among those who had first been induced to harbor evil thoughts about their victim. In Study 2, spectators of a peer's basketball-shooting performance were more likely to perceive that they had influenced his success if they had first generated positive visualizations consistent with that success. Observers privy to those spectators' visualizations made similar attributions about the spectators' influence. Finally, additional studies suggested that these results occur even when the thought-about outcome is viewed as unwanted by the thinker and even in field settings where the relevant outcome is occurring as part of a live athletic competition.

  5. On the use of ultracentrifugal devices for routine sample preparation in biomolecular magic-angle-spinning NMR

    PubMed Central

    Mandal, Abhishek; Boatz, Jennifer C.; Wheeler, Travis; van der Wel, Patrick C. A.

    2017-01-01

    A number of recent advances in the field of magic-angle-spinning (MAS) solid-state NMR have enabled its application to a range of biological systems of ever increasing complexity. To retain biological relevance, these samples are increasingly studied in a hydrated state. At the same time, experimental feasibility requires the sample preparation process to attain a high sample concentration within the final MAS rotor. We discuss these considerations, and how they have led to a number of different approaches to MAS NMR sample preparation. We describe our experience of how custom-made (or commercially available) ultracentrifugal devices can facilitate a simple, fast and reliable sample preparation process. A number of groups have since adopted such tools, in some cases to prepare samples for sedimentation-style MAS NMR experiments. Here we argue for a more widespread adoption of their use for routine MAS NMR sample preparation. PMID:28229262

  6. TRIP-ID: A tool for a smart and interactive identification of Magic Formula tyre model parameters from experimental data acquired on track or test rig

    NASA Astrophysics Data System (ADS)

    Farroni, Flavio; Lamberti, Raffaele; Mancinelli, Nicolò; Timpone, Francesco

    2018-03-01

    Tyres play a key role in ground vehicles' dynamics because they are responsible for traction, braking and cornering. A proper tyre-road interaction model is essential for a useful and reliable vehicle dynamics model. In the last two decades Pacejka's Magic Formula (MF) has become a standard in simulation field. This paper presents a Tool, called TRIP-ID (Tyre Road Interaction Parameters IDentification), developed to characterize and to identify with a high grade of accuracy and reliability MF micro-parameters from experimental data deriving from telemetry or from test rig. The tool guides interactively the user through the identification process on the basis of strong diagnostic considerations about the experimental data made evident by the tool itself. A motorsport application of the tool is shown as a case study.

  7. Albertus, "Magnus" or Magus? Magic, natural philosophy, and religious reform in the late middle ages.

    PubMed

    Collins, David J

    2010-01-01

    This article analyzes the fifteenth-century attempt by the Dominican order, especially in Cologne, to win canonization for the thirteenth-century natural philosopher Albert the Great. It shows how Albert's thought on natural philosophy and magic was understood and variously applied, how the Dominicans at Cologne composed his vitae, and how the order's Observant movement participated in these developments. It situates the canonization attempt at the intersection of two significant trends in which the order was a leading participant: first, the late medieval efforts to reform Christian society beginning with the religious life of monks and mendicants; second, the increasing concerns about the practice of learned and demonic mafic that laid groundwork for the witch-hunting of the early modern period. This article aims to shed light on intersections of science and religion -- their apprehension and negotiation -- at a decisive moment in European history for both fields of human endeavor.

  8. "You Will": Technology, Magic, and the Cultural Contexts of Technical Communication.

    ERIC Educational Resources Information Center

    Kitalong, Karla Saari

    2000-01-01

    Provides some background on the use of magical language in technical contexts, gives examples of magical discourse in technology advertisements and newsmagazine articles, and proposes a technical communication pedagogy of media analysis. Notes that the proposed pedagogy involves students conducting diagnostic critiques of media texts and affords…

  9. Magical Landscapes: Two Love Stories.

    ERIC Educational Resources Information Center

    Moore, John Noell

    2002-01-01

    Introduces two books about magic, one a collection of essays "Ex Libris: Confessions of a Common Reader," which describes the author's inherited lifelong passion for books and reading; and the other a novel, "Mangos, Bananas and Coconuts: A Cuban Love Story," which tells a story of love and magic that seems both real and…

  10. Magical Mysteries. Texas Reading Club, 1984. A Librarian's Planning Handbook.

    ERIC Educational Resources Information Center

    Oliver, Jim

    Designed to encourage library use by Texas youth, the Texas Reading Club programs usually include a structured reading program and a variety of entertaining literature-related storyhours, puppet shows, films, and other attractive happenings. This handbook for the 1984 theme--"magical mysteries"--focuses on mysteries, magic, and adventure…

  11. Redefining the magic square on numerical characters

    NASA Astrophysics Data System (ADS)

    Nasution, M. K. M.; Sawaluddin

    2018-02-01

    As a number system, the magic square is different from the others. Characteristic depends not only on size but also depends on numerical character in computation. This paper has redefined the term of magic square formally, by exposing the inductive general characteristics of cases to numerical ordering of numbers.

  12. Magic User’s Manual 2006

    DTIC Science & Technology

    2006-12-01

    K (M) M issioin Research MRC/WDC-R-556 MAGIC USER’S MANUAL 2006 Author(s): Larry Ludeking ATK Mission Research Contract No.: F49620-03-C-0030 L¾[iJiD... Magic Tool Suite for Windows. It uses the standard Windows Help so it is pretty self-explanatory. You can use the panel to the left to scan through... MAGIC Go to Part 2. MCL Commands Go to Part 3. Tirnc and Space Go to Part 4. Spatial Extensions Go to Part 5. Properties Go to Part 6. Algorithms Go

  13. A Compact Low-loss Magic-T using Microstrip-Slotline Transitions

    NASA Technical Reports Server (NTRS)

    U-yen, Kongpop; Wollack, Edward J.; Moseley, Samuel H.; Papapolymerou, John; Laskar, Joy

    2007-01-01

    The design of a compact low-loss magic-T is proposed. The planar magic-T incorporates the compact microstrip-slotline tee junction and small microstrip-slotline transition area to reduce slotline radiation. The experimental results show that the magic-T produces broadband in-phase and out-of-phase power combiner/divider responses, has an average in-band insertion loss of 0.3 dB and small in-band phase and amplitude imbalance of less than plus or minus 1.6 deg. and plus or minus 0.3 dB, respectively.

  14. The use of magical plants by curanderos in the Ecuador highlands

    PubMed Central

    Cavender, Anthony P; Albán, Manuel

    2009-01-01

    Although the use of plants for treating supernaturally caused illnesses (e.g., soul loss, evil wind, witchcraft) has been documented in the Ecuador highlands, so-called magical plants have received much less focused attention than plants used for treating naturalistic disorders. Drawing on interviews done in 2002 and 2003 with 116 curanderos residing in the Ecuador highlands, this paper examines the characteristics of plants identified as magical, how they are used, and how the study of magical plants provides insights into the mindscape of residents of the highlands. PMID:19161618

  15. Do cultural factors affect causal beliefs? Rational and magical thinking in Britain and Mexico.

    PubMed

    Subbotsky, Eugene; Quinteros, Graciela

    2002-11-01

    In two experiments, unusual phenomena (spontaneous destruction of objects in an empty wooden box) were demonstrated to adult participants living in rural communities in Mexico. These were accompanied by actions which had no physical link to the destroyed object but could suggest either scientifically based (the effect of an unknown physical device) or non-scientifically based (the effect of a 'magic spell') causal explanations of the event. The results were compared to the results of the matching two experiments from the earlier study made in Britain. The expectation that scientifically based explanations would prevail in British participants' judgments and behaviours, whereas Mexican participants would be more tolerant toward magical explanations, received only partial support. The prevalence of scientific explanations over magical explanations was evident in British participants' verbal judgments but not in Mexican participants' judgments. In their behavioural responses under the low-risk condition, British participants rejected magical explanations more frequently than did Mexican participants. However, when the risk of disregarding the possible causal effect of magic was increased, participants in both samples showed an equal degree of credulity in the possible effect of magic. The data are interpreted in terms of the relationships between scientific and 'folk' representations of causality and object permanence.

  16. Algebra Magic Tricks: Algecadabra! Volume 1.

    ERIC Educational Resources Information Center

    Edwards, Ronald

    This resource book contains 20 magic tricks based on the properties of whole numbers that are intended to spark the interest and imagination of students. Following each activity, students are asked to write about their discoveries and to create their own magic tricks. A matrix of skills for all the activities and lists of the materials required…

  17. Algebra Magic Tricks: Algecadabra! Volume 2.

    ERIC Educational Resources Information Center

    Edwards, Ronald

    This resource book contains 15 magic tricks based on the properties of whole numbers that are intended to spark the interest and imagination of students. Following each activity, students are asked to write about their discoveries and to create their own magic tricks. A matrix of skills for all the activities and lists of the materials required…

  18. A COAXIAL MAGIC-T

    DTIC Science & Technology

    Three different designs of coaxial hybrid junctions having perf ormance analogous to a wave-guide magic -T are discussed. The experimental results...loads, decoupling greater than 70 db can be obtained. An application of the magic -T in phase measurement is described which is independent of the signal amplitude and is similar to the homodyne system of phase measurement.

  19. A CMOS VLSI IC for Real-Time Opto-Electronic Two-Dimensional Histogram Generation

    DTIC Science & Technology

    1993-12-01

    large scale integration) design; MAGIC ; CMOS; optics; image processing; 93 16. PRICE CODE 17. SECURITY CLASSIFICATION 18. SECURITY CLASSIFICATiON 19...1. Sun SPARCstation ............. .............. 6 2. Magic .................. ................... 6 a. Peg ................. .................. 7 b...38 v APPENDIX B. MAGIC CELL LAYOUTS .... ............ .. 39 APPENDIX C: SIMULATION DATA ....... ............. .. 56 A. FINITE STATE MACHINE

  20. Magical Realist Pathways into and under the Psychotherapeutic Imaginary

    ERIC Educational Resources Information Center

    Speedy, Jane

    2011-01-01

    My experience of people's life stories from my work as a narrative therapist consistently destabilised distinctions between imagined/magical and real experiences. I came to realise that the day-to-day magical realist juxtapositions I came upon were encounters with people's daily lives, as lived, that have remained unacknowledged within the…

  1. Glamour and Spelling: Reclaiming Magical Thinking in the Composition Classroom.

    ERIC Educational Resources Information Center

    Wagner, Julia

    It is a good thing to demolish "magical thinking" if it refers to the view of language for which words have fixed, inevitable meanings. Words are often deprived of their meanings and reduced to verbal noises, producing involuntary responses like knee-reflexes. Various critics have discussed and written about the magical aspects of…

  2. Garden Gnomes: Magical or Tacky?

    ERIC Educational Resources Information Center

    Flynt, Deborah

    2012-01-01

    Garden gnomes: magical or tacky? Well, art is in the eye of the beholder, and for the author's advanced seventh-grade art class, garden gnomes are magical. Gnomes have a very long history, dating back to medieval times. A fairytale describes them as brownie-like creatures that are nocturnal helpers. In this article, the author describes how her…

  3. A framework for using magic to study the mind.

    PubMed

    Rensink, Ronald A; Kuhn, Gustav

    2014-01-01

    Over the centuries, magicians have developed extensive knowledge about the manipulation of the human mind-knowledge that has been largely ignored by psychology. It has recently been argued that this knowledge could help improve our understanding of human cognition and consciousness. But how might this be done? And how much could it ultimately contribute to the exploration of the human mind? We propose here a framework outlining how knowledge about magic can be used to help us understand the human mind. Various approaches-both old and new-are surveyed, in terms of four different levels. The first focuses on the methods in magic, using these to suggest new approaches to existing issues in psychology. The second focuses on the effects that magic can produce, such as the sense of wonder induced by seeing an apparently impossible event. Third is the consideration of magic tricks-methods and effects together-as phenomena of scientific interest in their own right. Finally, there is the organization of knowledge about magic into an informative whole, including the possibility of a science centered around the experience of wonder.

  4. A framework for using magic to study the mind

    PubMed Central

    Rensink, Ronald A.; Kuhn, Gustav

    2015-01-01

    Over the centuries, magicians have developed extensive knowledge about the manipulation of the human mind—knowledge that has been largely ignored by psychology. It has recently been argued that this knowledge could help improve our understanding of human cognition and consciousness. But how might this be done? And how much could it ultimately contribute to the exploration of the human mind? We propose here a framework outlining how knowledge about magic can be used to help us understand the human mind. Various approaches—both old and new—are surveyed, in terms of four different levels. The first focuses on the methods in magic, using these to suggest new approaches to existing issues in psychology. The second focuses on the effects that magic can produce, such as the sense of wonder induced by seeing an apparently impossible event. Third is the consideration of magic tricks—methods and effects together—as phenomena of scientific interest in their own right. Finally, there is the organization of knowledge about magic into an informative whole, including the possibility of a science centered around the experience of wonder. PMID:25698983

  5. Observations of VHE γ-Ray Sources with the MAGIC Telescope

    NASA Astrophysics Data System (ADS)

    Bartko, H.

    2008-10-01

    The MAGIC telescope with its 17m diameter mirror is today the largest operating single-dish Imaging Air Cherenkov Telescope (IACT). It is located on the Canary Island La Palma, at an altitude of 2200m above sea level, as part of the Roque de los Muchachos European Northern Observatory. The MAGIC telescope detects celestial very high energy γ-radiation in the energy band between about 50 GeV and 10 TeV. Since Autumn of 2004 MAGIC has been taking data routinely, observing various objects like supernova remnants (SNRs), γ-ray binaries, Pulsars, Active Galactic Nuclei (AGN) and Gamma-ray Bursts (GRB). We briefly describe the observational strategy, the procedure implemented for the data analysis, and discuss the results for individual sources. An outlook to the construction of the second MAGIC telescope is given.

  6. [Magical and religious healing in Byzantium].

    PubMed

    Józsa, László

    2010-01-01

    Religious and magical ways of healing have been known and practiced since the very beginning of human history. In the present article, the Byzantine philosophical, cultural, historical and "methodological" aspects of this way of healing are discussed. The article outlines the development of magic healing in Byzantium from the 4th to the 15th century. During this period magical therapy included the cult of patron saints--listed by the author--and pleading for divine intervention as well. The activity of "anargyroi" and the use of magical objects and amulets is also discussed in detail. Exorcism was also a part of religious therapy both against psychical and somatical diseases. In early Christianity, and especially in Byzantium the devil or other demons were also supposed to cause various somatical or psychical illnesses by "intrusion" or "internalisation," i.e. by possession or obsession of their victims.

  7. Maximum nonlocality and minimum uncertainty using magic states

    NASA Astrophysics Data System (ADS)

    Howard, Mark

    2015-04-01

    We prove that magic states from the Clifford hierarchy give optimal solutions for tasks involving nonlocality and entropic uncertainty with respect to Pauli measurements. For both the nonlocality and uncertainty tasks, stabilizer states are the worst possible pure states, so our solutions have an operational interpretation as being highly nonstabilizer. The optimal strategy for a qudit version of the Clauser-Horne-Shimony-Holt game in prime dimensions is achieved by measuring maximally entangled states that are isomorphic to single-qudit magic states. These magic states have an appealingly simple form, and our proof shows that they are "balanced" with respect to all but one of the mutually unbiased stabilizer bases. Of all equatorial qudit states, magic states minimize the average entropic uncertainties for collision entropy and also, for small prime dimensions, min-entropy, a fact that may have implications for cryptography.

  8. Implementing a Community-Driven Cyberinfrastructure Platform for the Paleo- and Rock Magnetic Scientific Fields that Generalizes to Other Geoscience Disciplines

    NASA Astrophysics Data System (ADS)

    Minnett, R.; Jarboe, N.; Koppers, A. A.; Tauxe, L.; Constable, C.

    2013-12-01

    EarthRef.org is a geoscience umbrella website for several databases and data and model repository portals. These portals, unified in the mandate to preserve their respective data and promote scientific collaboration in their fields, are also disparate in their schemata. The Magnetics Information Consortium (http://earthref.org/MagIC/) is a grass-roots cyberinfrastructure effort envisioned by the paleo- and rock magnetic scientific community to archive their wealth of peer-reviewed raw data and interpretations from studies on natural and synthetic samples and relies on a partially strict subsumptive hierarchical data model. The Geochemical Earth Reference Model (http://earthref.org/GERM/) portal focuses on the chemical characterization of the Earth and relies on two data schemata: a repository of peer-reviewed reservoir geochemistry, and a database of partition coefficients for rocks, minerals, and elements. The Seamount Biogeosciences Network (http://earthref.org/SBN/) encourages the collaboration between the diverse disciplines involved in seamount research and includes the Seamount Catalog (http://earthref.org/SC/) of bathymetry and morphology. All of these portals also depend on the EarthRef Reference Database (http://earthref.org/ERR/) for publication reference metadata and the EarthRef Digital Archive (http://earthref.org/ERDA/), a generic repository of data objects and their metadata. The development of the new MagIC Search Interface (http://earthref.org/MagIC/search/) centers on a reusable platform designed to be flexible enough for largely heterogeneous datasets and to scale up to datasets with tens of millions of records. The HTML5 web application and Oracle 11g database residing at the San Diego Supercomputer Center (SDSC) support the online contribution and editing of complex datasets in a spreadsheet environment and the browsing and filtering of these contributions in the context of thousands of other datasets. EarthRef.org is in the process of implementing this platform across all of its data portals in spite of the wide variety of data schemata and is dedicated to serving the geoscience community with as little effort from the end-users as possible.

  9. A Mo-95 and C-13 Solid-state NMR and Relativistic DFT Investigation of Mesitylenetricarbonylmolybdenum(0) -a Typical Transition Metal Piano-stool Complex

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bryce, David L.; Wasylishen, Roderick E.

    2002-06-21

    The chemical shift (CS) and electric field gradient (EFG) tensors in the piano-stool compound mesitylenetricarbonylmolybdenum(0), 1, have been investigated via {sup 95}Mo and {sup 13}C solid-state magic-angle spinning (MAS) NMR as well as relativistic zeroth-order regular approximation density functional theory (ZORA-DFT) calculations. Molybdenum-95 (I = 5/2) MAS NMR spectra acquired at 18.8 T are dominated by the anisotropic chemical shift interaction ({Omega} = 775 {+-} 30 ppm) rather than the 2nd-order quadrupolar interaction (C{sub Q} = -0.96 {+-} 0.15 MHz), an unusual situation for a quadrupolar nucleus. ZORA-DFT calculations of the {sup 95}Mo EFG and CS tensors are in agreementmore » with the experimental data. Mixing of appropriate occupied and virtual d-orbital dominated MOs in the region of the HOMO-LUMO gap are shown to be responsible for the large chemical shift anisotropy. The small, but non-negligible, {sup 95}Mo quadrupolar interaction is discussed in terms of the geometry about Mo. Carbon-13 CPMAS spectra acquired at 4.7 T demonstrate the crystallographic and magnetic nonequivalence of the twelve {sup 13}C nuclei in 1, despite the chemical equivalence of some of these nuclei in isotropic solutions. The principal components of the carbon CS tensors are determined via a Herzfeld-Berger analysis, and indicate that motion of the mesitylene ring is slow compared to a rate which would influence the carbon CS tensors (i.e. tens of {micro}s). ZORA-DFT calculations reproduce the experimental carbon CS tensors accurately. Oxygen-17 EFG and CS tensors for 1 are also calculated and discussed in terms of existing experimental data for related molybdenum carbonyl compounds. This work provides an example of the information available from combined multi-field solid-state multinuclear magnetic resonance and computational investigations of transition metal compounds, in particular the direct study of quadrupolar transition metal nuclei with relatively small magnetic moments.« less

  10. Logistical Support of AirLand Operations: Myth or Magic?

    DTIC Science & Technology

    1992-05-04

    I4 May 1992 Master’s Thesis, 4 Aug 91-5 Jun 92 4. TITLE AND SUBTITLE 5. FUNDING NUMBERS .Support of AirLand Operations: Myth or Magic 6. AUTHOR(S) HA•J...SUPPORT OF AIRLAND OPERATIONS: MYTH OR MAGIC A thesis nresented to the Faculty of the U.S. Army Command and General Staff College in oartial fulfillment of...inerati,,,: Myth or Magic . Aprroved by: .Theq is Comni tt-t- fTh~airrnan; J ),I i .5 .a rria A.n . T.T! 3:•, J!. Pnwe r. M’. P. A . " ,ý) VoD" Member

  11. Comparison of HELIX TWT Simulation Using 2-D PIC (Magic), 2-D Modal (Gator), and 1-D Modal (Christine) Methods

    DTIC Science & Technology

    1998-05-01

    Mission Research Corporation MRC/WDC-R-424 COMPARISON OF HELIX TWT SIMULATION USING 2-D PIC ( MAGIC ), 2-D MODAL (GATOR), AND 1-D MODAL (CHRISTINE...BRILLOUIN RUN 9 3.4 OUTLIER ELECTRON EFFECT IN GATOR 12 3.5 EMISSION CONDITION AND NONLAMINAR FLOW IN MAGIC 12 3.6 RADIAL SHEAR 13 SECTION 4. PPM B...Simulation using 2-D PIC ( MAGIC ), 2-D Modal (GATOR) and 1-D Modal (CHRISTINE) methods * D.N. Smithe(a), H. Freund(b), T. M. Antonsen Jr.,(b)’(c), E

  12. Optically guided atom interferometer tuned to magic wavelength

    NASA Astrophysics Data System (ADS)

    Akatsuka, Tomoya; Takahashi, Tadahiro; Katori, Hidetoshi

    2017-11-01

    We demonstrate an atom interferometer operating on the 1S0-3P0 clock transition of 87Sr atoms in a “magic” optical guide, where the light shift perturbations of the guiding potential are canceled. As a proof-of-principle demonstration, a Mach-Zehnder interferometer is set horizontally to map the acceleration introduced by the focused optical guide. This magic guide interferometer on the clock transition is applicable to atomic elements where magic wavelengths can be found. Possible applications of the magic guide interferometer, including a hollow-core fiber interferometer and gradiometer, are discussed.

  13. Review of fundamental physics results with the MAGIC telescopes

    NASA Astrophysics Data System (ADS)

    Rico, Javier

    2017-01-01

    The MAGIC Cherenkov telescopes are powerful tools for the exploration of the Physics frontiers, addressing topics such as the nature of dark matter and its distribution in the Universe, or the search for quantum gravitational effects in photon propagation. Since the beginning of operations in 2004, MAGIC has studied these questions thanks to hundreds of hours of observations of different targets, and has produced several high-impact results. Those include, significantly, the most constraining limits to the WIMP annihilation cross-section for particle masses above few hundred GeV, from observations of dwarf spheroidal (dSph) satellite galaxies. More recently, we have completed a combined analysis of MAGIC and Fermi-LAT observations of dSphs, obtaining limits for dark matter particle masses between 10 GeV and 100 TeV - the widest mass range ever explored by a single gamma-ray analysis - and improving the previously published Fermi-LAT and MAGIC results by up to a factor of two at certain masses. In this talk, I present an overview of the status and results of MAGIC Fundamental Physics projects, including our latest results concerning searches for Lorentz Invariance violation (LIV), and dark matter searches. I will propose the use of the framework developed for the MAGIC/Fermi-LAT joint analysis for the combination of results from the current generation of gamma-ray and neutrino detectors.

  14. The "Magic" String

    ERIC Educational Resources Information Center

    Hoover, Todd F.

    2010-01-01

    The "Magic" String is a discrepant event that includes a canister with what appears to be the end of two strings protruding from opposite sides of it. Due to the way the strings are attached inside the canister, it appears as if the strings can magically switch the way they are connected. When one string end is pulled, the observer's expectation…

  15. Pulling Words Out of a Hat: Magic in ESL Lessons.

    ERIC Educational Resources Information Center

    Friedenberg, Randi D.

    Magic motivates students to talk, and stimulates the affective domain. While watching magic, many people imagine how the effect is accomplished or how they might perform the trick if they were performing. This can be extended into an English lesson by using phrases such as, "If I were a magician, I could..." Total physical response…

  16. The Cultural Work of Magical Realism in Three Young Adult Novels

    ERIC Educational Resources Information Center

    Latham, Don

    2007-01-01

    Magical realism as a literary mode is often subversive and transgressive, questioning the values and assumptions of the dominant society that it depicts. Young adult literature, by contrast, is typically thought to serve a socializing function, helping to integrate young readers into adult society. What then is the cultural work of magical realism…

  17. Molecules, magic and forgetful fruit flies: the supernatural science of medical gas research.

    PubMed

    Mychaskiw, George

    2011-09-06

    Medical gas research often involves the study of molecules under extraphysiologic conditions, that is, conditions that do not exist in nature. This "supernatural" nature of medical gas research sometimes produces results that appear to be almost "magic" to those schooled in traditional physiology"Any sufficiently advanced technology is indistinguishable from magic".-Arthur C. Clarke.

  18. Development of next-generation mapping populations: Multi-parent Advanced Generation Inter-Cross (MAGIC) and Marker-Assisted Recurrent Selection (MARS) populations in peanut

    USDA-ARS?s Scientific Manuscript database

    Generation Inter-Cross (MAGIC) and Marker-Assisted Recurrent Selection (MARS) have been proposed and used in many crops to dissect complex traits or QTL. MAGIC allows for dissecting genomic structure, and for improving breeding populations by integrating multiple alleles from different parents. MAR...

  19. Elementary School Teachers' Perceptions toward ICT: The Case of Using Magic Board for Teaching Mathematics

    ERIC Educational Resources Information Center

    Yuan, Yuan; Lee, Chun-Yi

    2012-01-01

    This study aims at investigating elementary school teachers' perceptions toward to the use of ICT. Magic Board, an interactive web-based environment which provides a set of virtual manipulatives for elementary mathematics, is used as the case of ICT. After participating in Magic Board workshops, 250 elementary school teachers in Taiwan responded…

  20. 77 FR 70432 - Magic Valley Pipeline, L.P.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ... Pipeline, L.P.; Notice of Filing Take notice that on November 15, 2012, Magic Valley Pipeline, L.P. (Magic...: 5:00 p.m. Eastern Time on Tuesday, November 27, 2012. Dated: November 19, 2012. Kimberly D. Bose, Secretary. [FR Doc. 2012-28544 Filed 11-23-12; 8:45 am] BILLING CODE 6717-01-P ...

  1. Cloud-based design of high average power traveling wave linacs

    NASA Astrophysics Data System (ADS)

    Kutsaev, S. V.; Eidelman, Y.; Bruhwiler, D. L.; Moeller, P.; Nagler, R.; Barbe Welzel, J.

    2017-12-01

    The design of industrial high average power traveling wave linacs must accurately consider some specific effects. For example, acceleration of high current beam reduces power flow in the accelerating waveguide. Space charge may influence the stability of longitudinal or transverse beam dynamics. Accurate treatment of beam loading is central to the design of high-power TW accelerators, and it is especially difficult to model in the meter-scale region where the electrons are nonrelativistic. Currently, there are two types of available codes: tracking codes (e.g. PARMELA or ASTRA) that cannot solve self-consistent problems, and particle-in-cell codes (e.g. Magic 3D or CST Particle Studio) that can model the physics correctly but are very time-consuming and resource-demanding. Hellweg is a special tool for quick and accurate electron dynamics simulation in traveling wave accelerating structures. The underlying theory of this software is based on the differential equations of motion. The effects considered in this code include beam loading, space charge forces, and external magnetic fields. We present the current capabilities of the code, provide benchmarking results, and discuss future plans. We also describe the browser-based GUI for executing Hellweg in the cloud.

  2. Genetic algorithm optimized triply compensated pulses in NMR spectroscopy

    NASA Astrophysics Data System (ADS)

    Manu, V. S.; Veglia, Gianluigi

    2015-11-01

    Sensitivity and resolution in NMR experiments are affected by magnetic field inhomogeneities (of both external and RF), errors in pulse calibration, and offset effects due to finite length of RF pulses. To remedy these problems, built-in compensation mechanisms for these experimental imperfections are often necessary. Here, we propose a new family of phase-modulated constant-amplitude broadband pulses with high compensation for RF inhomogeneity and heteronuclear coupling evolution. These pulses were optimized using a genetic algorithm (GA), which consists in a global optimization method inspired by Nature's evolutionary processes. The newly designed π and π / 2 pulses belong to the 'type A' (or general rotors) symmetric composite pulses. These GA-optimized pulses are relatively short compared to other general rotors and can be used for excitation and inversion, as well as refocusing pulses in spin-echo experiments. The performance of the GA-optimized pulses was assessed in Magic Angle Spinning (MAS) solid-state NMR experiments using a crystalline U-13C, 15N NAVL peptide as well as U-13C, 15N microcrystalline ubiquitin. GA optimization of NMR pulse sequences opens a window for improving current experiments and designing new robust pulse sequences.

  3. Selective excitation enables assignment of proton resonances and {sup 1}H-{sup 1}H distance measurement in ultrafast magic angle spinning solid state NMR spectroscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Rongchun; Ramamoorthy, Ayyalusamy, E-mail: ramamoor@umich.edu

    2015-07-21

    Remarkable developments in ultrafast magic angle spinning (MAS) solid-state NMR spectroscopy enabled proton-based high-resolution multidimensional experiments on solids. To fully utilize the benefits rendered by proton-based ultrafast MAS experiments, assignment of {sup 1}H resonances becomes absolutely necessary. Herein, we propose an approach to identify different proton peaks by using dipolar-coupled heteronuclei such as {sup 13}C or {sup 15}N. In this method, after the initial preparation of proton magnetization and cross-polarization to {sup 13}C nuclei, transverse magnetization of desired {sup 13}C nuclei is selectively prepared by using DANTE (Delays Alternating with Nutations for Tailored Excitation) sequence and then, it is transferredmore » to bonded protons with a short-contact-time cross polarization. Our experimental results demonstrate that protons bonded to specific {sup 13}C atoms can be identified and overlapping proton peaks can also be assigned. In contrast to the regular 2D HETCOR experiment, only a few 1D experiments are required for the complete assignment of peaks in the proton spectrum. Furthermore, the finite-pulse radio frequency driven recoupling sequence could be incorporated right after the selection of specific proton signals to monitor the intensity buildup for other proton signals. This enables the extraction of {sup 1}H-{sup 1}H distances between different pairs of protons. Therefore, we believe that the proposed method will greatly aid in fast assignment of peaks in proton spectra and will be useful in the development of proton-based multi-dimensional solid-state NMR experiments to study atomic-level resolution structure and dynamics of solids.« less

  4. Study of lignification by noninvasive techniques in growing maize internodes. An investigation by Fourier transform infrared cross-polarization-magic angle spinning 13C-nuclear magnetic resonance spectroscopy and immunocytochemical transmission electron microscopy.

    PubMed Central

    Joseleau, J P; Ruel, K

    1997-01-01

    Noninvasive techniques were used for the study in situ of lignification in the maturing cell walls of the maize (Zea mays L.) stem. Within the longitudinal axis of a developing internode all of the stages of lignification can be found. The synthesis of the three types of lignins, p-hydroxyphenylpropane (H), guaiacyl (G), and syringyl (S), was investigated in situ by cross-polarization-magic angle spinning 13C-solid-state nuclear magnetic resonance, Fourier transform infrared spectroscopy, and immunocytochemical electron microscopy. The first lignin appearing in the parenchyma is of the G-type preceeding the incorporation of S nuclei in the later stages. However, in vascular bundles, typical absorption bands of S nuclei are visible in the Fourier transform infrared spectra at the earliest stage of lignification. Immunocytochemical determination of the three types of lignin in transmission electron microscopy was possible thanks to the use of antisera prepared against synthetic H, G, and the mixed GS dehydrogenative polymers (K. Ruel, O. Faix, J.P. Joseleau [1994] J Trace Microprobe Tech 12: 247-265). The specificity of the immunological probes demonstrated that there are differences in the relative temporal synthesis of the H, G, and GS lignins in the different tissues undergoing lignification. Considering the intermonomeric linkages predominating in the antigens used for the preparation of the immunological probes, the relative intensities of the labeling obtained provided, for the first time to our knowledge, information about the macromolecular nature of lignins (condensed versus noncondensed) in relation to their ultrastructural localization and development stage. PMID:9232887

  5. Optimal Control-Enabled Imaging and Spectroscopy using a Nanowire Magnetic Resonance Force Microscope

    NASA Astrophysics Data System (ADS)

    Rose, William; Haas, Holger; Chen, Angela; Cory, David; Budakian, Raffi

    Magnetic resonance imaging (MRI) is a powerful non-invasive technique that has transformed our ability to study the structure and function of biological systems. Key to its success has been the unique ability to combine imaging with magnetic resonance spectroscopy. Although it remains a significant challenge, there is considerable interest in extending MRI spectroscopy to the nanometer scale because it would provide a fundamentally new route for determining the structure and function of complex biomolecules. We present data taken with a nanowire magnetic resonance force microscopy (MRFM) setup. We show how the capabilities of this very sensitive spin-detection system can be extended to include spectroscopy and nanometer-scale imaging by combining optimal control theory (OCT) techniques with magic echo sequences. We apply OCT-based dynamical-decoupling pulses to nanoscale ensembles of proton spins in polystyrene, and demonstrate a 500-fold line-narrowing of the proton spin resonance, from 30 kHz to 60 Hz. We further demonstrate 1-D imaging over a 35-nm region with an average voxel size of 2.2 nm. Funding provided by the U.S. Army Research Office, Grant No. W911NF-12-1-0341.

  6. Geometrical, electronic, and magnetic properties of CunFe (n=1-12) clusters: A density functional study

    NASA Astrophysics Data System (ADS)

    Ling, Wang; Dong, Die; Shi-Jian, Wang; Zheng-Quan, Zhao

    2015-01-01

    The geometrical, electronic, and magnetic properties of small CunFe (n=1-12) clusters have been investigated by using density functional method B3LYP and LanL2DZ basis set. The structural search reveals that Fe atoms in low-energy CunFe isomers tend to occupy the position with the maximum coordination number. The ground state CunFe clusters possess planar structure for n=2-5 and three-dimensional (3D) structure for n=6-12. The electronic properties of CunFe clusters are analyzed through the averaged binding energy, the second-order energy difference and HOMO-LUMO energy gap. It is found that the magic numbers of stability are 1, 3, 7 and 9 for the ground state CunFe clusters. The energy gap of Fe-encapsulated cage clusters is smaller than that of other configurations. The Cu5Fe and Cu7Fe clusters have a very large energy gap (>2.4 eV). The vertical ionization potential (VIP), electron affinity (EA) and photoelectron spectra are also calculated and simulated theoretically for all the ground-state clusters. The magnetic moment analyses for the ground-state CunFe clusters show that Fe atom can enhance the magnetic moment of the host cluster and carries most of the total magnetic moment.

  7. Biological degradation of tannins in sericea lespedeza (Lespedeza cuneata) by the white rot fungi Ceriporiopsis subvermispora and Cyathus stercoreus analyzed by solid-state 13C nuclear magnetic resonance spectroscopy.

    PubMed Central

    Gamble, G R; Akin, D E; Makkar, H P; Becker, K

    1996-01-01

    Leaves of sericea lespedeza exhibit a high proportion of condensed tannin, resulting in poor forage quality. The white rot fungi Ceriporiopsis subvermispora and Cyathus sterocoreus are known to preferentially degrade lignin in a variety of plants and were evaluated for their ability to degrade condensed tannin from sericea leaves with the aim of improving digestibility. Relative levels of condensed tannin, cutin, pectin, and cellulose were monitored as a function of fungal treatment by solid-state cross-polarization and magic angle spinning 13C nuclear magnetic resonance spectroscopy. Total soluble phenolics, soluble tannins, and soluble and insoluble proanthocyanidin levels in fungus-treated and control samples were measured by established chemical techniques. Results indicate that both species of fungus preferentially degrade condensed tannin and that C. subvermispora is markedly superior to C. stercoreus in this capacity. PMID:8837414

  8. Magical thinking and decision-making strategies among late adolescent regular gamblers: A mediation model.

    PubMed

    Passanisi, Alessia; Craparo, Giuseppe; Pace, Ugo

    2017-08-01

    In the present study, the relation between the tendency to seek supernatural connections between external events and one's own thoughts, words, and actions and gambling among late adolescents has been studied. Psychologists have called this tendency magical thinking. The principal aim of the present study was to test the fit of an explanatory model of risk that starts from magical thinking and passes through maladaptive decision-making strategies, culminating with pathological gambling. Two hundred twenty-two Italian late adolescents, regularly attending bingo halls, aged between 19 and 21 years, completed measures on magical thinking, decision-making strategies, and gambling. Results highlight that young adults adopting dysfunctional modes of thought (i.e. magical thinking) tend to engage with maladaptive styles of decision-making that predispose them to gamble. Copyright © 2017 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  9. Molecules, magic and forgetful fruit flies: the supernatural science of medical gas research

    PubMed Central

    2011-01-01

    Medical gas research often involves the study of molecules under extraphysiologic conditions, that is, conditions that do not exist in nature. This "supernatural" nature of medical gas research sometimes produces results that appear to be almost "magic" to those schooled in traditional physiology "Any sufficiently advanced technology is indistinguishable from magic". -Arthur C. Clarke PMID:22146602

  10. The Magical Classroom: Exploring Science, Language, and Perception with Children.

    ERIC Educational Resources Information Center

    Strauss, Michael J.

    The science of magic is the subject of this book which also examines how to help children experience and describe the world, how to experiment and ask questions about it, and how to make decisions about what is true and what is not. Background information about the relationship between magic and science and the nature of effects and illusions are…

  11. Overview of MAGIC results

    NASA Astrophysics Data System (ADS)

    Rico, Javier; MAGIC Collaboration

    2016-04-01

    MAGIC is a system of two 17-m diameter Cherenkov telescopes, located at the Observatorio del Roque de los Muchachos, in the Canary island La Palma (Spain). MAGIC performs astronomical observations of gamma-ray sources in the energy range between 50 GeV and 10 TeV. The first MAGIC telescope has been operating since 2004, and in 2009 the system was completed with the second one. During 2011 and 2012 the electronics for the readout system were fully upgraded, and the camera of the first telescope replaced. After that, no major hardware interventions are foreseen in the next years, and the experiment has undertaken a final period of steady astronomical observations. MAGIC studies particle acceleration in the most violent cosmic environments, such as active galactic nuclei, gamma-ray bursts, pulsars, supernova remnants or binary systems. In addition, it addresses some fundamental questions of Physics, such as the origin of Galactic cosmic rays and the nature of dark matter. Moreover, by observing the gamma-ray emission from sources at cosmological distances, we measure the intensity and evolution of the extragalactic background radiation, and perform tests of Lorentz Invariance. In this paper I present the status and some of the latest results of the MAGIC gamma-ray telescopes.

  12. Real time dynamics of Si magic clusters mediating phase transformation: Si(111)-(1 × 1) to (7 × 7) reconstruction revisited

    NASA Astrophysics Data System (ADS)

    Ong, Wei Jie; Tok, Eng Soon

    2012-07-01

    Using Scanning Tunneling Microscope (STM), we show that the surface undergoes phase transformation from disordered "1 × 1" to (7 × 7) reconstruction which is mediated by the formation of Si magic clusters. Mono-disperse Si magic clusters of size ~ 13.5 ± 0.5 Å can be formed by heating the Si(111) surface to 1200 °C and quenching it to room temperature at cooling rates of at least 100 °C/min. The structure consists of 3 tetra-clusters of size ~ 4.5 Ǻ similar to the Si magic clusters that were formed from Si adatoms deposited by Si solid source on Si(111)-(7 × 7) [1]. Using real time STM scanning to probe the surface at ~ 400 °C, we show that Si magic clusters pop up from the (1 × 1) surface and form spontaneously during the phase transformation. This is attributed to the difference in atomic density between "disordered 1 × 1" and (7 × 7) surface structures which lead to the release of excess Si atoms onto the surface as magic clusters.

  13. The relationship between magical thinking, inferential confusion and obsessive-compulsive symptoms.

    PubMed

    Goods, N A R; Rees, C S; Egan, S J; Kane, R T

    2014-01-01

    Inferential confusion is an under-researched faulty reasoning process in obsessive-compulsive disorder (OCD). Based on an overreliance on imagined possibilities, it shares similarities with the extensively researched construct of thought-action fusion (TAF). While TAF has been proposed as a specific subset of the broader construct of magical thinking, the relationship between inferential confusion and magical thinking is unexplored. The present study investigated this relationship, and hypothesised that magical thinking would partially mediate the relationship between inferential confusion and obsessive-compulsive symptoms. A non-clinical sample of 201 participants (M = 34.94, SD = 15.88) were recruited via convenience sampling. Regression analyses found the hypothesised mediating relationship was supported, as magical thinking did partially mediate the relationship between inferential confusion and OC symptoms. Interestingly, inferential confusion had the stronger relationship with OC symptoms in comparison to the other predictor variables. Results suggest that inferential confusion can both directly and indirectly (via magical thinking) impact on OC symptoms. Future studies with clinical samples should further investigate these constructs to determine whether similar patterns emerge, as this may eventually inform which cognitive errors to target in treatment of OCD.

  14. Does magical thinking produce neutralising behaviour? An experimental investigation.

    PubMed

    Bocci, Laura; Gordon, P Kenneth

    2007-08-01

    Magical thinking is of relevance to obsessive compulsive disorder (OCD), and has been most widely investigated in relation to the cognitive bias known as thought-action fusion (TAF). This is seen as playing a role in the formation of fears about responsibility for harm. We suggest that magical thinking may also characterise some types of neutralising behaviour, which arise in response to those fears, and are a hallmark of the disorder. In an experimental study of 51 undergraduate students, we assessed whether the use of neutralising behaviours in response to an induction of fears of increasing likelihood for harm is related to a propensity for magical thinking. The 75.5% of participants demonstrated at least one form of neutralising behaviour in response to a TAF-induction task. Neutralising was associated with stronger and more persistent responses to the task, and with questionnaire measures of magical ideation. Those who neutralised did not report higher levels of OCD symptoms. It appears that neutralising is a common response in circumstances that provoke a sense of responsibility for harm. Its occurrence may be linked to magical thinking, however, the results from this experimental investigation suggested that this process may not be specific to OCD.

  15. Working wonders? investigating insight with magic tricks.

    PubMed

    Danek, Amory H; Fraps, Thomas; von Müller, Albrecht; Grothe, Benedikt; Ollinger, Michael

    2014-02-01

    We propose a new approach to differentiate between insight and noninsight problem solving, by introducing magic tricks as problem solving domain. We argue that magic tricks are ideally suited to investigate representational change, the key mechanism that yields sudden insight into the solution of a problem, because in order to gain insight into the magicians' secret method, observers must overcome implicit constraints and thus change their problem representation. In Experiment 1, 50 participants were exposed to 34 different magic tricks, asking them to find out how the trick was accomplished. Upon solving a trick, participants indicated if they had reached the solution either with or without insight. Insight was reported in 41.1% of solutions. The new task domain revealed differences in solution accuracy, time course and solution confidence with insight solutions being more likely to be true, reached earlier, and obtaining higher confidence ratings. In Experiment 2, we explored which role self-imposed constraints actually play in magic tricks. 62 participants were presented with 12 magic tricks. One group received verbal cues, providing solution relevant information without giving the solution away. The control group received no informative cue. Experiment 2 showed that participants' constraints were suggestible to verbal cues, resulting in higher solution rates. Thus, magic tricks provide more detailed information about the differences between insightful and noninsightful problem solving, and the underlying mechanisms that are necessary to have an insight. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. Determination of Membrane Protein Structure by Rotational Resonance NMR: Bacteriorhodopsin

    NASA Astrophysics Data System (ADS)

    Creuzet, F.; McDermott, A.; Gebhard, R.; van der Hoef, K.; Spijker-Assink, M. B.; Herzfeld, J.; Lugtenburg, J.; Levitt, M. H.; Griffin, R. G.

    1991-02-01

    Rotationally resonant magnetization exchange, a new nuclear magnetic resonance (NMR) technique for measuring internuclear distances between like spins in solids, was used to determine the distance between the C-8 and C-18 carbons of retinal in two model compounds and in the membrane protein bacteriorhodopsin. Magnetization transfer between inequivalent spins with an isotropic shift separation, δ, is driven by magic angle spinning at a speed ω_r that matches the rotational resonance condition δ = nω_r, where n is a small integer. The distances measured in this way for both the 6-s-cis- and 6-s-trans-retinoic acid model compounds agreed well with crystallographically known distances. In bacteriorhodopsin the exchange trajectory between C-8 and C-18 was in good agreement with the internuclear distance for a 6-s-trans configuration [4.2 angstroms (overset{circ}{mathrm A})] and inconsistent with that for a 6-s-cis configuration (3.1 overset{circ}{mathrm A}). The results illustrate that rotational resonance can be used for structural studies in membrane proteins and in other situations where diffraction and solution NMR techniques yield limited information.

  17. Using Magic Board as a Teaching Aid in Third Grader Learning of Area Concepts

    ERIC Educational Resources Information Center

    Chang, Wen-Long; Yuan, Yuan; Lee, Chun-Yi; Chen, Min-Hui; Huang, Wen-Guu

    2013-01-01

    The purpose of this study was to explore the impact of incorporating Magic Board in the instruction of concepts related to area. We adopted a non-equivalent quasi-experimental design and recruited participants from two classes of third-grade students in an elementary school in Taoyuan County, Taiwan. Magic Board was used as a teaching aid in the…

  18. CapDEM TD - Modeling and Simulation (Role and Tools) State of the Art Report

    DTIC Science & Technology

    2005-01-01

    office/wcm1/ornclinfn/ciefilnlt rnsnx [55] http://www.idefine.com/Tutorial/TutOiial%20Sales%20Page.htm [56] Gartner , " Magic Quadrant for Business ...21 Figure 3-5: Gartner Magic Quadrant For BPA, 2004 (56...of January 2004 Niche Players Visionaries ------- Completeness of Vision ..., Figure 3-5: Gartner Magic Quadrant For BPA, 2004 [56] Gartner , Inc

  19. Learning Activities That Combine Science Magic Activities with the 5E Instructional Model to Influence Secondary-School Students' Attitudes to Science

    ERIC Educational Resources Information Center

    Lin, Jang-Long; Cheng, Meng-Fei; Chang, Ying-Chi; Li, Hsiao-Wen; Chang, Jih-Yuan; Lin, Deng-Min

    2014-01-01

    The purpose of this study was to investigate how learning materials based on Science Magic activities affect student attitudes to science. A quasi-experimental design was conducted to explore the combination of Science Magic with the 5E Instructional Model to develop learning materials for teaching a science unit about friction. The participants…

  20. Magical Thinking in Judgments of Causation: Can Anomalous Phenomena Affect Ontological Causal Beliefs in Children and Adults?

    ERIC Educational Resources Information Center

    Subbotsky, Eugene

    2004-01-01

    In four experiments, 4-, 5-, 6- and 9-year-old children and adults were tested on the entrenchment of their magical beliefs and their beliefs in the universal power of physical causality. In Experiment 1, even 4-year-olds showed some understanding of the difference between ordinary and anomalous (magical) causal events, but only 6-year-olds and…

  1. The Ghost in the Machine: Why and How the Belief in Magic Survives in the Rational Mind

    ERIC Educational Resources Information Center

    Subbotsky, Eugene

    2011-01-01

    Since the time of Galileo (1564-1642), Western civilization has increasingly fallen under the spell of science. Despite this fact, anthropological and psychological research has shown that magical beliefs are present in both children and adults in modern industrial cultures. How can a belief in magic coexist with a belief in science in the mind of…

  2. Francesca Lia Block's Use of Enchantment: Teenagers' Need for Magic in the Real World.

    ERIC Educational Resources Information Center

    Warner, Lois L.

    2002-01-01

    Considers how Francesca Lia Block's melding of the magic and the ordinary makes her work special. Suggests that magic is what makes people dream, and that the teen years is a great time to dream because there is still time to make dreams come true. Presents a nine-item annotated bibliography of titles for adolescents by Block. (SG)

  3. Near-Infrared (NIR) Spectroscopy of Synthetic Hydroxyapatites and Human Dental Tissues.

    PubMed

    Kolmas, Joanna; Marek, Dariusz; Kolodziejski, Waclaw

    2015-08-01

    Near-infrared spectroscopy (NIR) was used to analyze synthetic hydroxyapatite calcined at various temperatures, synthetic carbonated hydroxyapatite, and human hard dental tissues (enamel and dentin). The NIR bands of those materials in the combination, first-overtone, and second-overtone spectral regions were assigned and evaluated for structural characterization. They were attributed to adsorbed and structural water, structural hydroxyl (OH) groups and surface P-OH groups. The NIR spectral features were quantitatively discussed in view of proton solid-state magic-angle spinning nuclear magnetic resonance ((1)H MAS NMR) results. We conclude that the NIR spectra of apatites are useful in the structural characterization of synthetic and biogenic apatites.

  4. Atmospheric monitoring in MAGIC and data corrections

    NASA Astrophysics Data System (ADS)

    Fruck, Christian; Gaug, Markus

    2015-03-01

    A method for analyzing returns of a custom-made "micro"-LIDAR system, operated alongside the two MAGIC telescopes is presented. This method allows for calculating the transmission through the atmospheric boundary layer as well as thin cloud layers. This is achieved by applying exponential fits to regions of the back-scattering signal that are dominated by Rayleigh scattering. Making this real-time transmission information available for the MAGIC data stream allows to apply atmospheric corrections later on in the analysis. Such corrections allow for extending the effective observation time of MAGIC by including data taken under adverse atmospheric conditions. In the future they will help reducing the systematic uncertainties of energy and flux.

  5. Magical ideation modulates spatial behavior.

    PubMed

    Mohr, Christine; Bracha, H Stefan; Brugger, Peter

    2003-01-01

    Previous research has found that animals as well as persons with psychotic disorders preferentially orient away from the cerebral hemisphere with the more active dopamine system. This study investigated the modulation of spatial behavior by a mode of thinking reminiscent of the positive symptoms of psychosis. In a non-treatment-seeking sample of healthy volunteers (20 women and 16 men), the authors assessed the lateral biases in turning and veering behavior and in line bisection as a function of their magical ideation, that is, a mild form of schizotypy. Across tasks, pronounced magical ideation was associated with reduced right-sided orientation preferences. This finding suggests a relative hyperdopaminergia of the right hemisphere as the biological basis of magical ideation.

  6. Freud, Piaget, or neither? Beliefs in controlling others by wishful thinking and magical behavior in young children.

    PubMed

    Vikan, A; Clausen, S E

    1993-09-01

    Tests showed that 4- to 6-year-old children believe that people can be influenced or "controlled" both by thinking (e.g., both wishful thinking and magical behavior) and by realistic means (e.g., positive reinforcement, example, and group pressure). Belief in control by thinking did not vary by the subjects' sex or age, influence type (wishing or magical behavior), or target response (behavior, emotion, or thought). Quantitative measures, however, suggested that magical behavior was seen by subjects as being more efficient than wishing, and that emotion was considered easier to influence than thinking. Beliefs in control by thinking were not related to a measure of fantasy-reality differentiation (realism).

  7. Solid-state NMR adiabatic TOBSY sequences provide enhanced sensitivity for multidimensional high-resolution magic-angle-spinning 1H MR spectroscopy

    NASA Astrophysics Data System (ADS)

    Andronesi, Ovidiu C.; Mintzopoulos, Dionyssios; Struppe, Jochem; Black, Peter M.; Tzika, A. Aria

    2008-08-01

    We propose a solid-state NMR method that maximizes the advantages of high-resolution magic-angle-spinning (HRMAS) applied to intact biopsies when compared to more conventional liquid-state NMR approaches. Theoretical treatment, numerical simulations and experimental results on intact human brain biopsies are presented. Experimentally, it is proven that an optimized adiabatic TOBSY (TOtal through Bond correlation SpectroscopY) solid-state NMR pulse sequence for two-dimensional 1H- 1H homonuclear scalar-coupling longitudinal isotropic mixing provides a 20%-50% improvement in signal-to-noise ratio relative to its liquid-state analogue TOCSY (TOtal Correlation SpectroscopY). For this purpose we have refined the C9151 symmetry-based 13C TOBSY pulse sequence for 1H MRS use and compared it to MLEV-16 TOCSY sequence. Both sequences were rotor-synchronized and implemented using WURST-8 adiabatic inversion pulses. As discussed theoretically and shown in simulations, the improved magnetization-transfer comes from actively removing residual dipolar couplings from the average Hamiltonian. Importantly, the solid-state NMR techniques are tailored to perform measurements at low temperatures where sample degradation is reduced. This is the first demonstration of such a concept for HRMAS metabolic profiling of disease processes, including cancer, from biopsies requiring reduced sample degradation for further genomic analysis.

  8. Study of the ferroelastic phase transition in the tetraethylammonium compound [N(C{sub 2}H{sub 5}){sub 4}]{sub 2}ZnBr{sub 4} by magic-angle spinning and static NMR

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lim, Ae Ran, E-mail: aeranlim@hanmail.net, E-mail: arlim@jj.ac.kr

    The ferroelastic phase transition of tetraethylammonium compound [N(C{sub 2}H{sub 5}){sub 4}]{sub 2}ZnBr{sub 4} at the phase transition temperature (T{sub C}) = 283 K was characterized by magic-angle spinning (MAS) and static nuclear magnetic resonance (NMR), and confirmed by optical polarizing spectroscopy. The structural geometry near T{sub C} was studied in terms of the chemical shifts and the spin-lattice relaxation times T{sub 1ρ} in the rotating frame for {sup 1}H MAS NMR and {sup 13}C cross-polarization (CP)/MAS NMR. The two inequivalent ethyl groups were distinguishable in the {sup 13}C NMR spectrum, and the T{sub 1ρ} results indicate that they undergo tumblingmore » motion above T{sub C} in a coupled manner. From the {sup 14}N NMR results, the two nitrogen nuclei in the N(C{sub 2}H{sub 5}){sub 4}{sup +} ions were distinguishable above T{sub C}, and the splitting in the spectra below T{sub C} was related to the ferroelastic domains with different orientations.« less

  9. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mukherjee, G.; Pai, H.

    High spin states in Bismuth and Thallium nuclei near the Z = 82 shell closure and Cesium nuclei near the N = 82 shell closure in A = 190 and A = 130 regions, respectively, have been experimentally investigated using heavy-ion fusion evaporation reaction and by detecting the gamma rays using the Indian National Gamma Array (INGA). Interesting shape properties in these transitional nuclei have been observed. The results were compared with the neighboring nuclei in these two regions. The total Routhian surface (TRS) calculations have been performed for a better understanding of the observed properties. In mass region Amore » = 190, a change in shape from spherical to deformed has been observd around neutron number N = 112 for the Bi (Z = 83) isotopes with proton number above the magic gap Z = 82, whereas, the shape of Tl (Z = 81) isotopes with proton number below the magic gap Z = 82 remains stable as a function of neutron number. An important transition from aplanar to planar configuration of angular momentum vectors leading to the occurance of nuclar chirality and magnetic rotation, respectively, has been proposed for the unique parity πh{sub 11/2}⊗νh{sub 11/2} configuration in Cs isotopes in the mass region A ∼ 130 around neutron number N = 79. These results are in commensurate with the TRS calculations.« less

  10. Perturbation of nuclear spin polarizations in solid state NMR of nitroxide-doped samples by magic-angle spinning without microwaves.

    PubMed

    Thurber, Kent R; Tycko, Robert

    2014-05-14

    We report solid state (13)C and (1)H nuclear magnetic resonance (NMR) experiments with magic-angle spinning (MAS) on frozen solutions containing nitroxide-based paramagnetic dopants that indicate significant perturbations of nuclear spin polarizations without microwave irradiation. At temperatures near 25 K, (1)H and cross-polarized (13)C NMR signals from (15)N,(13)C-labeled L-alanine in trinitroxide-doped glycerol/water are reduced by factors as large as six compared to signals from samples without nitroxide doping. Without MAS or at temperatures near 100 K, differences between signals with and without nitroxide doping are much smaller. We attribute most of the reduction of NMR signals under MAS near 25 K to nuclear spin depolarization through the cross-effect dynamic nuclear polarization mechanism, in which three-spin flips drive nuclear polarizations toward equilibrium with spin polarization differences between electron pairs. When T1e is sufficiently long relative to the MAS rotation period, the distribution of electron spin polarization across the nitroxide electron paramagnetic resonance lineshape can be very different from the corresponding distribution in a static sample at thermal equilibrium, leading to the observed effects. We describe three-spin and 3000-spin calculations that qualitatively reproduce the experimental observations.

  11. Multidimensional High-Resolution Magic Angle Spinning and Solution-State NMR Characterization of 13C-labeled Plant Metabolites and Lignocellulose

    PubMed Central

    Mori, Tetsuya; Tsuboi, Yuuri; Ishida, Nobuhiro; Nishikubo, Nobuyuki; Demura, Taku; Kikuchi, Jun

    2015-01-01

    Lignocellulose, which includes mainly cellulose, hemicellulose, and lignin, is a potential resource for the production of chemicals and for other applications. For effective production of materials derived from biomass, it is important to characterize the metabolites and polymeric components of the biomass. Nuclear magnetic resonance (NMR) spectroscopy has been used to identify biomass components; however, the NMR spectra of metabolites and lignocellulose components are ambiguously assigned in many cases due to overlapping chemical shift peaks. Using our 13C-labeling technique in higher plants such as poplar samples, we demonstrated that overlapping peaks could be resolved by three-dimensional NMR experiments to more accurately assign chemical shifts compared with two-dimensional NMR measurements. Metabolites of the 13C-poplar were measured by high-resolution magic angle spinning NMR spectroscopy, which allows sample analysis without solvent extraction, while lignocellulose components of the 13C-poplar dissolved in dimethylsulfoxide/pyridine solvent were analyzed by solution-state NMR techniques. Using these methods, we were able to unambiguously assign chemical shifts of small and macromolecular components in 13C-poplar samples. Furthermore, using samples of less than 5 mg, we could differentiate between two kinds of genes that were overexpressed in poplar samples, which produced clearly modified plant cell wall components. PMID:26143886

  12. Identification and onset of inertial modes in the wide-gap spherical Couette system

    NASA Astrophysics Data System (ADS)

    Barik, A.; Wicht, J.; Triana, S. A.; Hoff, M.

    2016-12-01

    The spherical Couette system consists of two concentric rotating spheres with a fluid filling the shell in between. The system has been studied for a long time by fluid dynamicists and is ideal for studying flow instabilities due to differential rotation and the interaction of the same with magnetic fields - important for understanding dynamics of planetary and stellar interiors. The system is also a basis for a new generation of dynamo experiments because of its closer geometrical resemblance to real astrophysical objects as compared to past experiments. We simulate this system using the two different pseudo-spectral codes MagIC and XSHELLS. We focus here on a very interesting and general instability in this system - inertial modes. A rotating body of fluid is known to sustain oscillatory waves due to the restoring action of the Coriolis force. In a bounded container, these form a discrete spectrum called inertial modes. These modes have been analytically known for a rotating full sphere for over a century now. In a spherical shell, they cannot be formulated analytically. However, many of these inertial modes are observed in spherical Couette experiments as well as in simulations. Past studies have tried to explain the onset of these modes invoking wave over-reflection or critical layer instabilities on the cylinder tangent to the inner sphere. In this study, we present the inertial modes found in our simulations and try to explain their onset as secondary instabilities due to the destabilization of the fundamental non-axisymmetric instability, forming a triadic resonance with the fundamental instability. We run various simulations varying the rotation rate of the inner sphere, while keeping the rotation rate of the outer sphere constant. We track velocities and induced magnetic field and produce spectrograms similar to those of the experiments. Our results match very well the experimental data from spherical Couette set-ups at BTU Cottbus and the University of Maryland.

  13. Distillation with Sublogarithmic Overhead.

    PubMed

    Hastings, Matthew B; Haah, Jeongwan

    2018-02-02

    It has been conjectured that, for any distillation protocol for magic states for the T gate, the number of noisy input magic states required per output magic state at output error rate ε is Ω[log(1/ε)]. We show that this conjecture is false. We find a family of quantum error correcting codes of parameters ⟦∑[under i=w+1][over m](m/i),∑[under i=0][over w](m/i),∑[under i=w+1][over r+1](r+1/i)⟧ for any integers m>2r, r>w≥0, by puncturing quantum Reed-Muller codes. When m>νr, our code admits a transversal logical gate at the νth level of Clifford hierarchy. In a distillation protocol for magic states at the level ν=3 (T gate), the ratio of input to output magic states is O(log^{γ}(1/ε)), where γ=log(n/k)/log(d)<0.678 for some m, r, w. The smallest code in our family for which γ<1 is on ≈2^{58} qubits.

  14. Need for cognition moderates paranormal beliefs and magical ideation in inconsistent-handers.

    PubMed

    Prichard, Eric C; Christman, Stephen D

    2016-01-01

    A growing literature suggests that degree of handedness predicts gullibility and magical ideation. Inconsistent-handers (people who use their non-dominant hand for at least one common manual activity) report more magical ideation and are more gullible. The current study tested whether this effect is moderated by need for cognition. One hundred eighteen university students completed questionnaires assessing handedness, self-reported paranormal beliefs, and self-reported need for cognition. Handedness (Inconsistent vs. Consistent Right) and Need for Cognition (High vs. Low) were treated as categorical predictors. Both paranormal beliefs and magical ideation served as dependent variable's in separate analyses. Neither set of tests yielded main effects for handedness or need for cognition. However, there were a significant handedness by need for cognition interactions. Post-hoc comparisons revealed that low, but not high, need for cognition inconsistent-handers reported relatively elevated levels of paranormal belief and magical ideation. A secondary set of tests treating the predictor variables as continuous instead of categorical obtained the same overall pattern.

  15. Magical thinking in narratives of adolescent cutters.

    PubMed

    Gregory, Robert J; Mustata, Georgian T

    2012-08-01

    Adolescents sometimes cut themselves to relieve distress; however, the mechanism is unknown. Previous studies have linked self-injury to deficits in processing emotions symbolically through language. To investigate expressive language of adolescent cutters, the authors analyzed 100 narratives posted on the Internet. Most narratives (n = 66) displayed idiosyncratic use of language indicating poor differentiation between the real and the symbolic, such as blood substituting for negative emotions, which can then be released from the self; or emotional pain magically transforming into physical pain, which can then be managed. This kind of magical thinking correlated with cutting to relieve distress, to see blood, and to feel pain, but negatively correlated with complex representation of people, understanding social causality, and self-esteem. The results suggest that magical thinking represents a pre-symbolic mental state that processes and organizes distressing emotions through body schema. Magical thinking thus provides a plausible mechanism for why cutting works. Copyright © 2012 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  16. Probing α-relaxation with nuclear magnetic resonance echo decay and relaxation: a study on nitrile butadiene rubber.

    PubMed

    Sturniolo, Simone; Pieruccini, Marco; Corti, Maurizio; Rigamonti, Attilio

    2013-01-01

    One dimensional (1)H NMR measurements have been performed to probe slow molecular motions in nitrile butadiene rubber (NBR) around its calorimetric glass transition temperature Tg. The purpose is to show how software aided data analysis can extract meaningful dynamical data from these measurements. Spin-lattice relaxation time, free induction decay (FID) and magic sandwich echo (MSE) measurements have been carried out at different values of the static field, as a function of temperature. It has been evidenced how the efficiency of the MSE signal in reconstructing the original FID exhibits a sudden minimum at a given temperature, with a slight dependence from the measuring frequency. Computer simulations performed with the software SPINEVOLUTION have shown that the minimum in the efficiency reconstruction of the MSE signal corresponds to the average motional frequency taking a value around the inter-proton coupling. The FID signals have been fitted with a truncated form of a newly derived exact correlation function for the transverse magnetization of a dipolar interacting spin pair, which allows one to avoid the restriction of the stationary and Gaussian approximations. A direct estimate of the conformational dynamics on approaching the Tg is obtained, and the results are in agreement with the analysis performed via the MSE reconstruction efficiency. The occurrence of a wide distribution of correlation frequencies for the chains motion, with a Vogel-Fulcher type temperature dependence, is addressed. A route for a fruitful study of the dynamics accompanying the glass transition by a variety of NMR measurements is thus proposed. Copyright © 2013 Elsevier Inc. All rights reserved.

  17. Nuclear Magnetic Resonance Observations of Octahedral Aluminum in Forsterite, Clinoenstatite and Periclase.

    NASA Astrophysics Data System (ADS)

    McCarty, R. J.; Stebbins, J. F.

    2015-12-01

    This research seeks to constrain the crystallographic site preferences of aluminum in forsterite, clinoenstatite and periclase, mantle minerals in which this element is only found at low concentrations. Improved site preference information will help constrain thermodynamic descriptions of the substitution mechanisms, making them more useful to geobarometric and geothermometric techniques. Using high field magic angle spinning nuclear magnetic resonance (NMR) and electron probe microanalysis (EPMA), we constrain the site preferences of minor and trace amounts (2000 to 400 mol ppm) of aluminum in extremely pure synthetic forsterite, clinoenstatite and periclase. The primary challenge of this research is determining how much of each of the aluminum species observed by NMR in the bulk sample (abundances and coordinations) resides in the major synthesized mineral. In our samples, the aluminum partitions between small amounts (often <1%) of impurity phases with high aluminum concentrations, such as glass and accessory crystals, and the major, intended phase with low aluminum concentrations. We use EPMA composition maps to locate scarce impurity phases and EPMA point analyses to determine the aluminum concentrations in both the intended major phase and in the impurity phases. Long NMR acquisitions (several days) and careful subtraction of rotor background signals (present in even 'low-Al' zirconia rotor materials) are required to obtain adequate signal-to-noise ratios at such low concentrations. Ordered octahedral aluminum has been identified in forsterite, clinoenstatite, and periclase. Disordered 4, 5 and 6 coordinated aluminum species have also been observed, but it is still unclear if the disordered species are in the major mineral phases, the impurity phases or both.

  18. Cost-Benefit Analysis For Alternative Low-Emission Surface Preparation/ Depainting Technologies for Structural Steel

    NASA Technical Reports Server (NTRS)

    Lewis, Pattie

    2007-01-01

    Stennis Space Center (SSC), Kennedy Space Center (KSC) and Air Force Space Command (AFSPC) identified particulate emissions and waste generated from the depainting process of steel structures as hazardous materials to be eliminated or reduced. A Potential Alternatives Report, Potential Alternatives Report for Validation of Alternative Low Emission Surface Preparation/Depainting Technologies for Structural Steel, provided a technical analyses of identified alternatives to the current coating removal processes, criteria used to select alternatives for further analysis, and a list of those alternatives recommended for testing. The initial coating removal alternatives list was compiled using literature searches and stakeholder recommendations. The involved project participants initially considered approximately 13 alternatives. In late 2003, core project members selected the following depainting processes to be further evaluated: (1) Plastic Blast Media-Quickstrip(R)-A. (2) Hard Abrasive-Steel-Magic(R). (3) Sponge Blasting-Sponge-Jet(R). (4) Liquid Nitrogen-NItroJet(R). (5) Mechanical Removal with Vacuum Attachment-DESCO and OCM Clean-Air (6) Laser Coating Removal Alternatives were tested in accordance with the Joint Test Protocol for Validation of Alternative Low-Emission Surface Preparation/Depainting Technologies for Structural Steel, and the Field Evaluation Test Plan for Validation of Alternative Low-Emission Surface Preparation/Depainting Technologies for Structural Steel. Results of the testing are documented in the Joint Test Report. This Cost-Benefit Analysis (CBA) focuses on the three alternatives (Quickstrip(R)-A, SteelMagic (R), and Sponge-Jet(R)) that were considered viable alternatives for large area operations based on the results of the field demonstration and lab testing. This CBA was created to help participants determine if implementation of the candidate alternatives is economically justified. Each of the alternatives examined reduced Environmental Activity (EA) Costs-those costs associated with complying with environmental regulations. One alternative, Steel-Magic(R), also showed reduced Direct Costs and reduced total costs.

  19. What's Magic about Magic Numbers? Chunking and Data Compression in Short-Term Memory

    ERIC Educational Resources Information Center

    Mathy, Fabien; Feldman, Jacob

    2012-01-01

    Short term memory is famously limited in capacity to Miller's (1956) magic number 7 plus or minus 2--or, in many more recent studies, about 4 plus or minus 1 "chunks" of information. But the definition of "chunk" in this context has never been clear, referring only to a set of items that are treated collectively as a single unit. We propose a new…

  20. Western aeronautical test range real-time graphics software package MAGIC

    NASA Technical Reports Server (NTRS)

    Malone, Jacqueline C.; Moore, Archie L.

    1988-01-01

    The master graphics interactive console (MAGIC) software package used on the Western Aeronautical Test Range (WATR) of the NASA Ames Research Center is described. MAGIC is a resident real-time research tool available to flight researchers-scientists in the NASA mission control centers of the WATR at the Dryden Flight Research Facility at Edwards, California. The hardware configuration and capabilities of the real-time software package are also discussed.

  1. The Phantom Vanish Magic Trick: Investigating the Disappearance of a Non-existent Object in a Dynamic Scene

    PubMed Central

    Tompkins, Matthew L.; Woods, Andy T.; Aimola Davies, Anne M.

    2016-01-01

    Drawing inspiration from sleight-of-hand magic tricks, we developed an experimental paradigm to investigate whether magicians’ misdirection techniques could be used to induce the misperception of “phantom” objects. While previous experiments investigating sleight-of-hand magic tricks have focused on creating false assumptions about the movement of an object in a scene, our experiment investigated creating false assumptions about the presence of an object in a scene. Participants watched a sequence of silent videos depicting a magician performing with a single object. Following each video, participants were asked to write a description of the events in the video. In the final video, participants watched the Phantom Vanish Magic Trick, a novel magic trick developed for this experiment, in which the magician pantomimed the actions of presenting an object and then making it magically disappear. No object was presented during the final video. The silent videos precluded the use of false verbal suggestions, and participants were not asked leading questions about the objects. Nevertheless, 32% of participants reported having visual impressions of non-existent objects. These findings support an inferential model of perception, wherein top-down expectations can be manipulated by the magician to generate vivid illusory experiences, even in the absence of corresponding bottom-up information. PMID:27493635

  2. Setting the magic angle for fast magic-angle spinning probes.

    PubMed

    Penzel, Susanne; Smith, Albert A; Ernst, Matthias; Meier, Beat H

    2018-06-15

    Fast magic-angle spinning, coupled with 1 H detection is a powerful method to improve spectral resolution and signal to noise in solid-state NMR spectra. Commercial probes now provide spinning frequencies in excess of 100 kHz. Then, one has sufficient resolution in the 1 H dimension to directly detect protons, which have a gyromagnetic ratio approximately four times larger than 13 C spins. However, the gains in sensitivity can quickly be lost if the rotation angle is not set precisely. The most common method of magic-angle calibration is to optimize the number of rotary echoes, or sideband intensity, observed on a sample of KBr. However, this typically uses relatively low spinning frequencies, where the spinning of fast-MAS probes is often unstable, and detection on the 13 C channel, for which fast-MAS probes are typically not optimized. Therefore, we compare the KBr-based optimization of the magic angle with two alternative approaches: optimization of the splitting observed in 13 C-labeled glycine-ethylester on the carbonyl due to the Cα-C' J-coupling, or optimization of the H-N J-coupling spin echo in the protein sample itself. The latter method has the particular advantage that no separate sample is necessary for the magic-angle optimization. Copyright © 2018. Published by Elsevier Inc.

  3. The 'Magic Light': A Discussion on Laser Ethics.

    PubMed

    Stylianou, Andreas; Talias, Michael A

    2015-08-01

    Innovations in technology and science form novel fields that, although beneficial, introduce new bio-ethical issues. In their short history, lasers have greatly influenced our everyday lives, especially in medicine. This paper focuses particularly on medical and para-medical laser ethics and their origins, and presents the complex relationships within laser ethics through a three-dimensional matrix model. The term 'laser' and the myth of the 'magic light' can be identified as landmarks for laser related ethical issues. These ethical issues are divided into five major groups: (1) media, marketing, and advertising; (2) economic outcomes; (3) user training; (4) the user-patient/client relationship; and (5) other issues. In addition, issues arising from two of the most common applications of lasers, laser eye surgery and laser tattoo removal, are discussed. The aim of this paper is to demonstrate that the use of medical and para-medical lasers has so greatly influenced our lives that the scientific community must initiate an earnest discussion of medical laser ethics.

  4. [The patient and medicine in contemporary Kazakhstan, attitudes towards bio-medicine and complementary medicine].

    PubMed

    Penkala-Gawecka, D

    2001-01-01

    The article discusses society's attitudes towards bio-medicine and complementary medicine in Kazakhstan around the end of the 20th century. It presents the transformation of the health-care system in independent Kazakhstan and its influence on the health situation of the population as well as public opinion on bio-medicine. Presented is a broad spectrum of various fields of complementary medicine which achieved great popularity especially during the 1990s. Among the reasons for that growing popularity appears to be public disenchantment with the collapsing state health-care system which is costly and ineffective. At the same time, an important factor is the durability of traditional beliefs of a magical type which is behind the wide use of nonconventional magic-religious practices -- spells and prayers. Overall public socio-economic malaise and a fear of the future are conducive to a general increase of interest in mystical beliefs and occult practices as well as a paranormal phenomena, and the flourishing of complementary medicine naturally fits into that scheme.

  5. Biomolecular solid state NMR with magic-angle spinning at 25K.

    PubMed

    Thurber, Kent R; Tycko, Robert

    2008-12-01

    A magic-angle spinning (MAS) probe has been constructed which allows the sample to be cooled with helium, while the MAS bearing and drive gases are nitrogen. The sample can be cooled to 25K using roughly 3 L/h of liquid helium, while the 4-mm diameter rotor spins at 6.7 kHz with good stability (+/-5 Hz) for many hours. Proton decoupling fields up to at least 130 kHz can be applied. This helium-cooled MAS probe enables a variety of one-dimensional and two-dimensional NMR experiments on biomolecular solids and other materials at low temperatures, with signal-to-noise proportional to 1/T. We show examples of low-temperature (13)C NMR data for two biomolecular samples, namely the peptide Abeta(14-23) in the form of amyloid fibrils and the protein HP35 in frozen glycerol/water solution. Issues related to temperature calibration, spin-lattice relaxation at low temperatures, paramagnetic doping of frozen solutions, and (13)C MAS NMR linewidths are discussed.

  6. Phonon-particle coupling effects in odd-even mass differences of semi-magic nuclei

    NASA Astrophysics Data System (ADS)

    Saperstein, E. E.; Baldo, M.; Pankratov, S. S.; Tolokonnikov, S. V.

    2017-11-01

    A method to evaluate the particle-phonon coupling (PC) corrections to the single-particle energies in semi-magic nuclei, based on a direct solving the Dyson equation with PC corrected mass operator, is used for finding the odd-even mass difference between 18 even Pb isotopes and their odd-proton neighbors. The Fayans energy density functional (EDF) DF3-a is used which gives rather high accuracy of the predictions for these mass differences already on the mean-field level, with the average deviation from the existing experimental data equal to 0.389 MeV. It is only a bit worse than the corresponding value of 0.333 MeV for the Skyrme EDF HFB-17, which belongs to a family of Skyrme EDFs with the highest overall accuracy in describing the nuclear masses. Account for the PC corrections induced by the low-laying phonons 2 1 + and 3 1 - significantly diminishes the deviation of the theory from the data till 0.218 MeV.

  7. Turn on, tune in, but don't drop out: The impact of neo-liberalism on magic mushroom users' (in)ability to imagine collectivist social worlds.

    PubMed

    Riley, Sarah; Thompson, James; Griffin, Christine

    2010-11-01

    Between 2002 and 2005 fresh or unprepared psilocin-based 'magic' mushrooms were legal to possess and traffic in the UK, and commercial sales demonstrated a significant market for this hallucinogenic drug. During and after this time there has been relatively little analysis concerning how magic mushroom users accounted for their drug use, nor on the wider political and cultural discourses that might have shaped this sense making. In this paper we present a critical analysis of contemporary discourses around magic mushroom use in the UK through a multi-level discourse analysis of focus group data from 20 magic mushroom users (13 male and 7 female, mean age 25 years), taken at a time when magic mushrooms were being legally sold in the UK. Locating participants' use of magic mushrooms within the context of a culture of intoxication, neo-liberalism and the legacy of 1960s psychedelic philosophy, we identify six interpretative repertoires in their talk, which were subsumed within two overarching discourses. The first discourse drew on neo-liberal rhetoric, constructing participants as rational risk managing subjects engaged in a form of calculated hedonism that was legitimated as an act of personal freedom and consumer choice. The second discourse, identified as 'post-psychedelic', both celebrated and problematised a collective, connected 'hippy' form of spirituality. The paper analyses the relationships between identity, consumption and citizenship by arguing that people's ability to imagine collectivist, spiritual or interconnected social worlds has been contained within neo-liberalism rhetoric. Copyright © 2010 Elsevier B.V. All rights reserved.

  8. Magic Pools: Parallel Assessment of Transposon Delivery Vectors in Bacteria

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Hualan; Price, Morgan N.; Waters, Robert Jordan

    Transposon mutagenesis coupled to next-generation sequencing (TnSeq) is a powerful approach for discovering the functions of bacterial genes. However, the development of a suitable TnSeq strategy for a given bacterium can be costly and time-consuming. To meet this challenge, we describe a part-based strategy for constructing libraries of hundreds of transposon delivery vectors, which we term “magic pools.” Within a magic pool, each transposon vector has a different combination of upstream sequences (promoters and ribosome binding sites) and antibiotic resistance markers as well as a random DNA barcode sequence, which allows the tracking of each vector during mutagenesis experiments. Tomore » identify an efficient vector for a given bacterium, we mutagenize it with a magic pool and sequence the resulting insertions; we then use this efficient vector to generate a large mutant library. We used the magic pool strategy to construct transposon mutant libraries in five genera of bacteria, including three genera of the phylumBacteroidetes. IMPORTANCEMolecular genetics is indispensable for interrogating the physiology of bacteria. However, the development of a functional genetic system for any given bacterium can be time-consuming. Here, we present a streamlined approach for identifying an effective transposon mutagenesis system for a new bacterium. Our strategy first involves the construction of hundreds of different transposon vector variants, which we term a “magic pool.” The efficacy of each vector in a magic pool is monitored in parallel using a unique DNA barcode that is introduced into each vector design. Using archived DNA “parts,” we next reassemble an effective vector for making a whole-genome transposon mutant library that is suitable for large-scale interrogation of gene function using competitive growth assays. Here, we demonstrate the utility of the magic pool system to make mutant libraries in five genera of bacteria.« less

  9. Magic Pools: Parallel Assessment of Transposon Delivery Vectors in Bacteria

    DOE PAGES

    Liu, Hualan; Price, Morgan N.; Waters, Robert Jordan; ...

    2018-01-16

    Transposon mutagenesis coupled to next-generation sequencing (TnSeq) is a powerful approach for discovering the functions of bacterial genes. However, the development of a suitable TnSeq strategy for a given bacterium can be costly and time-consuming. To meet this challenge, we describe a part-based strategy for constructing libraries of hundreds of transposon delivery vectors, which we term “magic pools.” Within a magic pool, each transposon vector has a different combination of upstream sequences (promoters and ribosome binding sites) and antibiotic resistance markers as well as a random DNA barcode sequence, which allows the tracking of each vector during mutagenesis experiments. Tomore » identify an efficient vector for a given bacterium, we mutagenize it with a magic pool and sequence the resulting insertions; we then use this efficient vector to generate a large mutant library. We used the magic pool strategy to construct transposon mutant libraries in five genera of bacteria, including three genera of the phylumBacteroidetes. IMPORTANCEMolecular genetics is indispensable for interrogating the physiology of bacteria. However, the development of a functional genetic system for any given bacterium can be time-consuming. Here, we present a streamlined approach for identifying an effective transposon mutagenesis system for a new bacterium. Our strategy first involves the construction of hundreds of different transposon vector variants, which we term a “magic pool.” The efficacy of each vector in a magic pool is monitored in parallel using a unique DNA barcode that is introduced into each vector design. Using archived DNA “parts,” we next reassemble an effective vector for making a whole-genome transposon mutant library that is suitable for large-scale interrogation of gene function using competitive growth assays. Here, we demonstrate the utility of the magic pool system to make mutant libraries in five genera of bacteria.« less

  10. Characterization of a novel two dimensional diode array the "magic plate" as a radiation detector for radiation therapy treatment.

    PubMed

    Wong, J H D; Fuduli, I; Carolan, M; Petasecca, M; Lerch, M L F; Perevertaylo, V L; Metcalfe, P; Rosenfeld, A B

    2012-05-01

    Intensity modulated radiation therapy (IMRT) utilizes the technology of multileaf collimators to deliver highly modulated and complex radiation treatment. Dosimetric verification of the IMRT treatment requires the verification of the delivered dose distribution. Two dimensional ion chamber or diode arrays are gaining popularity as a dosimeter of choice due to their real time feedback compared to film dosimetry. This paper describes the characterization of a novel 2D diode array, which has been named the "magic plate" (MP). It was designed to function as a 2D transmission detector as well as a planar detector for dose distribution measurements in a solid water phantom for the dosimetric verification of IMRT treatment delivery. The prototype MP is an 11 × 11 detector array based on thin (50 μm) epitaxial diode technology mounted on a 0.6 mm thick Kapton substrate using a proprietary "drop-in" technology developed by the Centre for Medical Radiation Physics, University of Wollongong. A full characterization of the detector was performed, including radiation damage study, dose per pulse effect, percent depth dose comparison with CC13 ion chamber and build up characteristics with a parallel plane ion chamber measurements, dose linearity, energy response and angular response. Postirradiated magic plate diodes showed a reproducibility of 2.1%. The MP dose per pulse response decreased at higher dose rates while at lower dose rates the MP appears to be dose rate independent. The depth dose measurement of the MP agrees with ion chamber depth dose measurements to within 0.7% while dose linearity was excellent. MP showed angular response dependency due to the anisotropy of the silicon diode with the maximum variation in angular response of 10.8% at gantry angle 180°. Angular dependence was within 3.5% for the gantry angles ± 75°. The field size dependence of the MP at isocenter agrees with ion chamber measurement to within 1.1%. In the beam perturbation study, the surface dose increased by 12.1% for a 30 × 30 cm(2) field size at the source to detector distance (SDD) of 80 cm whilst the transmission for the MP was 99%. The radiation response of the magic plate was successfully characterized. The array of epitaxial silicon based detectors with "drop-in" packaging showed properties suitable to be used as a simplified multipurpose and nonperturbing 2D radiation detector for radiation therapy dosimetric verification.

  11. It's a kind of magic-what self-reports can reveal about the phenomenology of insight problem solving.

    PubMed

    Danek, Amory H; Fraps, Thomas; von Müller, Albrecht; Grothe, Benedikt; Öllinger, Michael

    2014-01-01

    Magic tricks usually remain a mystery to the observer. For the sake of science, we offered participants the opportunity to discover the magician's secret method by repeatedly presenting the same trick and asking them to find out how the trick worked. In the context of insightful problem solving, the present work investigated the emotions that participants experience upon solving a magic trick. We assumed that these emotions form the typical "Aha! experience" that accompanies insightful solutions to difficult problems. We aimed to show that Aha! experiences can be triggered by magic tricks and to systematically explore the phenomenology of the Aha! experience by breaking it down into five previously postulated dimensions. 34 video clips of different magic tricks were presented up to three times to 50 participants who had to find out how the trick was accomplished, and to indicate whether they had experienced an Aha! during the solving process. Participants then performed a comprehensive quantitative and qualitative assessment of their Aha! experiences which was repeated after 14 days to control for its reliability. 41% of all suggested solutions were accompanied by an Aha! experience. The quantitative assessment remained stable across time in all five dimensions. Happiness was rated as the most important dimension. This primacy of positive emotions was also reflected in participants' qualitative self-reports which contained more emotional than cognitive aspects. Implementing magic tricks as problem solving task, we could show that strong Aha! experiences can be triggered if a trick is solved. We could at least partially capture the phenomenology of Aha! by identifying one prevailing aspect (positive emotions), a new aspect (release of tension upon gaining insight into a magic trick) and one less important aspect (impasse).

  12. Compact Low-Loss Planar Magic-T

    NASA Technical Reports Server (NTRS)

    U-yen, Kongpop; Wollack, Edward J.; Doiron, Terence; Moseley, Sameul H.

    2008-01-01

    This design allows broadband power combining with high isolation between the H port and E port, and achieves a lower insertion loss than any other broadband planar magic-T. Passive micro wave/millimeter-wave signal power is combined both in-phase and out-of-phase at the ports, with the phase error being less than 1 , which is limited by port impedance. The in-phase signal combiner consists of two quarter-wavelength-long transmission lines combined at the microstrip line junction. The out-of-phase signal combiner consists of two half-wavelength-long transmission lines combined in series. Structural symmetry creates a virtual ground plane at the combining junction, and the combined signal is converted from microstrip line to slotline. Optimum realizable characteristic impedances are used so that the magic-T provides broadband response with low return loss. The magic-T is used in microwave and millimeter-wave frequencies, with the operating bandwidth being approximately 100 percent. The minimum isolation obtainable is 32 dB from port E to port H. The magic-T VSWR is less than 1.1 in the operating band. Operating temperature is mainly dependent on the variation in the dielectric constant of the substrate. Using crystallized substrate, the invention can operate in an extremely broad range of temperatures (from 0 to 400 K). It has a very high reliability because it has no moving parts and requires no maintenance, though it is desirable that the magic-T operate in a low-humidity environment. Fabrication of this design is very simple, using only two metallized layers. No bond wires, via holes, or air bridges are required. Additionally, this magic-T can operate as an individual component without auxiliary components.

  13. Rescuing magical thinking from the jaws of social determinism.

    PubMed

    Chandler, M

    1997-12-01

    Although there is otherwise much to recommend it, by riveting attention too narrowly on the contents of magical thought, and by recasting what is left of process in exclusively substantiative terms, this target article works to create the unwarranted impression that the magical thoughts of children and adults are all of a common piece. This commentary reads these oversights and omissions as symptoms of an unspoken new-situationalism working behind the back of Woolley's review.

  14. Airbag Trail Dubbed 'Magic Carpet'

    NASA Technical Reports Server (NTRS)

    2004-01-01

    [figure removed for brevity, see original site] Click on the image for Airbag Trail Dubbed 'Magic Carpet' (QTVR)

    [figure removed for brevity, see original site] [figure removed for brevity, see original site] Magic Carpet Close-upMagic Carpet Close-up HD

    This section of the first color image from the Mars Exploration Rover Spirit has been further processed to produce a sharper look at a trail left by the one of rover's airbags. The drag mark was made after the rover landed and its airbags were deflated and retracted. Scientists have dubbed the region the 'Magic Carpet' after a crumpled portion of the soil that appears to have been peeled away (lower left side of the drag mark). Rocks were also dragged by the airbags, leaving impressions and 'bow waves' in the soil. The mission team plans to drive the rover over to this site to look for additional clues about the composition of the martian soil. This image was taken by Spirit's panoramic camera.

    This extreme close-up image (see insets above) highlights the martian feature that scientists have named 'Magic Carpet' because of its resemblance to a crumpled carpet fold. Scientists think the soil here may have detached from its underlying layer, possibly due to interaction with the Mars Exploration Rover Spirit's airbag after landing. This image was taken on Mars by the rover's panoramic camera.

  15. Role of magical thinking in obsessive-compulsive symptoms in an undergraduate sample.

    PubMed

    Einstein, Danielle A; Menzies, Ross G

    2004-01-01

    Thought action fusion (TAF) is an important presenting feature of many individuals with obsessive-compulsive disorder (OCD). "Magical thinking" is a similar construct (developed within the literature on schizotypy) that may provide a more accurate depiction of difficulties encountered by individuals with OCD. This study seeks to examine relationships between components of magical thinking, TAF, and superstitiousness; establish the extent to which these constructs are independently related to OCD proneness; and establish the extent to which these biased reasoning styles are related to each of the major OCD symptom clusters (e.g., washing, checking). The Padua Inventory (PI), the Maudsley Obsessional-Compulsive Inventory (MOCI), the Magical Ideation Scale (MI), the Lucky Behaviours (Lbeh) and Lucky Beliefs (Lbel) Scales, and the Thought Action Fusion-Revised scale (TAF-R) were given to a cohort of 86 undergraduate students. Of all the measures, the MI scale was found to be the most strongly related to obsessive-compulsive symptoms. Large and significant relationships between MI scores and the two measures of OCD (i.e., MOCI and PI) were obtained even when alternative mediators (i.e., Lbeh, Lbel, TAF-R) were held constant. No other variable remained significantly related to the MOCI or PI when magical ideation scores were held constant. The findings suggest that a general magical thinking tendency may underpin previous observed links between superstitiousness, thought action fusion, and OCD severity. Copyright 2004 Wiley-Liss, Inc.

  16. Step-by-step magic state encoding for efficient fault-tolerant quantum computation

    PubMed Central

    Goto, Hayato

    2014-01-01

    Quantum error correction allows one to make quantum computers fault-tolerant against unavoidable errors due to decoherence and imperfect physical gate operations. However, the fault-tolerant quantum computation requires impractically large computational resources for useful applications. This is a current major obstacle to the realization of a quantum computer. In particular, magic state distillation, which is a standard approach to universality, consumes the most resources in fault-tolerant quantum computation. For the resource problem, here we propose step-by-step magic state encoding for concatenated quantum codes, where magic states are encoded step by step from the physical level to the logical one. To manage errors during the encoding, we carefully use error detection. Since the sizes of intermediate codes are small, it is expected that the resource overheads will become lower than previous approaches based on the distillation at the logical level. Our simulation results suggest that the resource requirements for a logical magic state will become comparable to those for a single logical controlled-NOT gate. Thus, the present method opens a new possibility for efficient fault-tolerant quantum computation. PMID:25511387

  17. Step-by-step magic state encoding for efficient fault-tolerant quantum computation.

    PubMed

    Goto, Hayato

    2014-12-16

    Quantum error correction allows one to make quantum computers fault-tolerant against unavoidable errors due to decoherence and imperfect physical gate operations. However, the fault-tolerant quantum computation requires impractically large computational resources for useful applications. This is a current major obstacle to the realization of a quantum computer. In particular, magic state distillation, which is a standard approach to universality, consumes the most resources in fault-tolerant quantum computation. For the resource problem, here we propose step-by-step magic state encoding for concatenated quantum codes, where magic states are encoded step by step from the physical level to the logical one. To manage errors during the encoding, we carefully use error detection. Since the sizes of intermediate codes are small, it is expected that the resource overheads will become lower than previous approaches based on the distillation at the logical level. Our simulation results suggest that the resource requirements for a logical magic state will become comparable to those for a single logical controlled-NOT gate. Thus, the present method opens a new possibility for efficient fault-tolerant quantum computation.

  18. Gamma-ray blazars: the combined AGILE and MAGIC views

    NASA Astrophysics Data System (ADS)

    Persic, M.; De Angelis, A.; Longo, F.; Tavani, M.

    The large FOV of the AGILE Gamma-Ray Imaging Detector (GRID), 2.5 sr, will allow the whole sky to be surveyed once every 10 days in the 30 MeV - 50 GeV energy band down to 0.05 Crab Units. This fact gives the opportunity of performing the first flux-limited, high-energy g-ray all-sky survey. The high Galactic latitude point-source population is expected to be largely dominated by blazars. Several tens of blazars are expected to be detected by AGILE (e.g., Costamante & Ghisellini 2002), about half of which accessible to the ground-based MAGIC Cherenkov telescope. The latter can then carry out pointed observations of this subset of AGILE sources in the 50GeV - 10TeV band. Given the comparable sensitivities of AGILE/GRID and MAGIC in adjacent energy bands where the emitted radiation is produced by the same (e.g., SSC) mechanism, we expect that most of these sources can be detected by MAGIC. We expect this broadband g-ray strategy to enable discovery by MAGIC of 10-15 previously unknown TeV blazars.

  19. Quantum computation with realistic magic-state factories

    NASA Astrophysics Data System (ADS)

    O'Gorman, Joe; Campbell, Earl T.

    2017-03-01

    Leading approaches to fault-tolerant quantum computation dedicate a significant portion of the hardware to computational factories that churn out high-fidelity ancillas called magic states. Consequently, efficient and realistic factory design is of paramount importance. Here we present the most detailed resource assessment to date of magic-state factories within a surface code quantum computer, along the way introducing a number of techniques. We show that the block codes of Bravyi and Haah [Phys. Rev. A 86, 052329 (2012), 10.1103/PhysRevA.86.052329] have been systematically undervalued; we track correlated errors both numerically and analytically, providing fidelity estimates without appeal to the union bound. We also introduce a subsystem code realization of these protocols with constant time and low ancilla cost. Additionally, we confirm that magic-state factories have space-time costs that scale as a constant factor of surface code costs. We find that the magic-state factory required for postclassical factoring can be as small as 6.3 million data qubits, ignoring ancilla qubits, assuming 10-4 error gates and the availability of long-range interactions.

  20. Assessment of Magical Beliefs about Food and Health.

    PubMed

    Lindeman, M; Keskivaara, P; Roschier, M

    2000-03-01

    The Magical Beliefs About Food and Health scale (MFH) was developed to assess individual differences in the tendency to adopt eating and health instructions that many magazines, health care books and food ideologies regard as valid but which obey universal laws of similarity and contagion. In a study of 216 individuals, the total MFH score showed good internal consistency and it was associated with various validity criteria as hypothesized (e.g. vegetarianism and other ideological commitments to food choice, female gender, increased neuroticism, experiential thinking, positive attitudes towards alternative medicine, low sensation seeking and endorsement of universalism values). Factor analysis yielded two factors: General Magical Beliefs and Animal Products as Food Contaminants. In addition, three other items (the Animal Products as Personality Contaminants scale) cross-loaded on the two factors. The factor structure and test-retest reliability were confirmed with separate samples. The results showed that the total MFH score is a reliable and valid measure of magical food and health beliefs, and that the subscales may prove useful when a multidimensional assessment of magical beliefs is needed.

  1. Heteronuclear proton assisted recoupling

    NASA Astrophysics Data System (ADS)

    De Paëpe, Gaël; Lewandowski, Józef R.; Loquet, Antoine; Eddy, Matt; Megy, Simon; Böckmann, Anja; Griffin, Robert G.

    2011-03-01

    We describe a theoretical framework for understanding the heteronuclear version of the third spin assisted recoupling polarization transfer mechanism and demonstrate its potential for detecting long-distance intramolecular and intermolecular 15N-13C contacts in biomolecular systems. The pulse sequence, proton assisted insensitive nuclei cross polarization (PAIN-CP) relies on a cross term between 1H-15N and 1H-13C dipolar couplings to mediate zero- and/or double-quantum 15N-13C recoupling. In particular, using average Hamiltonian theory we derive effective Hamiltonians for PAIN-CP and show that the transfer is mediated by trilinear terms of the form N±C∓Hz (ZQ) or N±C±Hz (DQ) depending on the rf field strengths employed. We use analytical and numerical simulations to explain the structure of the PAIN-CP optimization maps and to delineate the appropriate matching conditions. We also detail the dependence of the PAIN-CP polarization transfer with respect to local molecular geometry and explain the observed reduction in dipolar truncation. In addition, we demonstrate the utility of PAIN-CP in structural studies with 15N-13C spectra of two uniformly 13C,15N labeled model microcrystalline proteins—GB1, a 56 amino acid peptide, and Crh, a 85 amino acid domain swapped dimer (MW = 2 × 10.4 kDa). The spectra acquired at high magic angle spinning frequencies (ωr/2π > 20 kHz) and magnetic fields (ω0H/2π = 700-900 MHz) using moderate rf fields, yield multiple long-distance intramonomer and intermonomer 15N-13C contacts. We use these distance restraints, in combination with the available x-ray structure as a homology model, to perform a calculation of the monomer subunit of the Crh protein.

  2. Proton assisted recoupling and protein structure determination

    NASA Astrophysics Data System (ADS)

    de Paëpe, Gaël; Lewandowski, Józef R.; Loquet, Antoine; Böckmann, Anja; Griffin, Robert G.

    2008-12-01

    We introduce a homonuclear version of third spin assisted recoupling, a second-order mechanism that can be used for polarization transfer between 13C or 15N spins in magic angle spinning (MAS) NMR experiments, particularly at high spinning frequencies employed in contemporary high field MAS experiments. The resulting sequence, which we refer to as proton assisted recoupling (PAR), relies on a cross-term between 1H-13C (or 1H-15N) couplings to mediate zero quantum 13C-13C (or 15N-15N recoupling). In particular, using average Hamiltonian theory we derive an effective Hamiltonian for PAR and show that the transfer is mediated by trilinear terms of the form C1+/-C2-/+HZ for 13C-13C recoupling experiments (or N1+/-N2-/+HZ for 15N-15N). We use analytical and numerical simulations to explain the structure of the PAR optimization maps and to delineate the PAR matching conditions. We also detail the PAR polarization transfer dependence with respect to the local molecular geometry and explain the observed reduction in dipolar truncation. Finally, we demonstrate the utility of PAR in structural studies of proteins with 13C-13C spectra of uniformly 13C, 15N labeled microcrystalline Crh, a 85 amino acid model protein that forms a domain swapped dimer (MW=2×10.4 kDa). The spectra, which were acquired at high MAS frequencies (ωr2π>20 kHz) and magnetic fields (750-900 MHz 1H frequencies) using moderate rf fields, exhibit numerous cross peaks corresponding to long (up to 6-7 A˚) 13C-13C distances which are particularly useful in protein structure determination. Using results from PAR spectra we calculate the structure of the Crh protein.

  3. Solid-state 11B and 13C NMR, IR, and X-ray crystallographic characterization of selected arylboronic acids and their catechol cyclic esters.

    PubMed

    Oh, Se-Woung; Weiss, Joseph W E; Kerneghan, Phillip A; Korobkov, Ilia; Maly, Kenneth E; Bryce, David L

    2012-05-01

    Nine arylboronic acids, seven arylboronic catechol cyclic esters, and two trimeric arylboronic anhydrides (boroxines) are investigated using (11)B solid-state NMR spectroscopy at three different magnetic field strengths (9.4, 11.7, and 21.1 T). Through the analysis of spectra of static and magic-angle spinning samples, the (11)B electric field gradient and chemical shift tensors are determined. The effects of relaxation anisotropy and nutation field strength on the (11)B NMR line shapes are investigated. Infrared spectroscopy was also used to help identify peaks in the NMR spectra as being due to the anhydride form in some of the arylboronic acid samples. Seven new X-ray crystallographic structures are reported. Calculations of the (11)B NMR parameters are performed using cluster model and periodic gauge-including projector-augmented wave (GIPAW) density functional theory (DFT) approaches, and the results are compared with the experimental values. Carbon-13 solid-state NMR experiments and spectral simulations are applied to determine the chemical shifts of the ipso carbons of the samples. One bond indirect (13)C-(11)B spin-spin (J) coupling constants are also measured experimentally and compared with calculated values. The (11)B/(10)B isotope effect on the (13)C chemical shift of the ipso carbons of arylboronic acids and their catechol esters, as well as residual dipolar coupling, is discussed. Overall, this combined X-ray, NMR, IR, and computational study provides valuable new insights into the relationship between NMR parameters and the structure of boronic acids and esters. Copyright © 2012 John Wiley & Sons, Ltd.

  4. Observation of Galactic Sources of Very High Energy γ-RAYS with the Magic Telescope

    NASA Astrophysics Data System (ADS)

    Bartko, H.

    The MAGIC telescope with its 17m diameter mirror is today the largest operating single-dish Imaging Air Cherenkov Telescope (IACT). It is located on the Canary Island La Palma, at an altitude of 2200 m above sea level, as part of the Roque de los Muchachos European Northern Observatory. The MAGIC telescope detects celestial very high energy γ-radiation in the energy band between about 50 GeV and 10 TeV. Since the autumn of 2004 MAGIC has been taking data routinely, observing various objects, like supernova remnants (SNRs), γ-ray binaries, Pulsars, Active Galactic Nuclei (AGN) and Gamma-ray Bursts (GRB). We briefly describe the observational strategy, the procedure implemented for the data analysis, and discuss the results of observations of Galactic Sources.

  5. The permanence of mental objects: testing magical thinking on perceived and imaginary realities.

    PubMed

    Subbotsky, Eugene

    2005-03-01

    This study tested participants' preparedness to acknowledge that an object could change as a result of magical intervention. Six- and 9-year-old children and adults treated perceived and imagined objects as being equally permanent. Adults treated a fantastic object as significantly less permanent than either perceived or imagined objects. Results were similar when a different type of mental-physical causality--a participant's own wish--was examined. Adults were also tested on the permanence of personally significant imagined objects (participants' images of their future lives). Although almost all participants claimed that they did not believe in magic, in test trials they were not prepared to rule out the possibility that their future lives could be affected by a magical curse. Copyright 2005 APA, all rights reserved.

  6. VLSI Research

    DTIC Science & Technology

    1984-04-01

    Ousterhout, G.T. Hamachi, R.N. Mayo, W.S. Scott, and G.S. Taylor , "A Collection of Papers on Magic," Technical Report No. UCB/CSD 83/154, Computer Science...Division, University of California, Berkeley, December 1983. (3) J.K Ousterhout, G.T. Hamachi, R.N. Mayo, W.S. Scott, and G.S. Taylor , "Magic: A...VLSI Layout System." to appear, Slst Design Automation Confer- ence, June 1984. (4) G.S. Taylor and J.K Ousterhout, "Magic’s Incremental Design-Rule

  7. MAGIC discovers VHE gamma-ray emission from the blazar 1ES 1727+502

    NASA Astrophysics Data System (ADS)

    Mariotti, Mose

    2011-11-01

    The MAGIC Collaboration reports the discovery of Very High Energy (VHE; E>100 GeV) gamma-ray emission from the BL Lac object 1ES 1727+502 (also known as OT546) with redshift z=0.055. The source was selected from the compilation of Costamante, L. & Ghisellini, G. 2002, A&A, 384, 56. Previous observations with the single MAGIC-I telescope yielded an upper limit on the level of 11.8% of the Crab Nebula flux above 140 GeV (J.

  8. Physical aging in graphite/epoxy composites

    NASA Technical Reports Server (NTRS)

    Kong, E. S. W.

    1983-01-01

    Sub-Tg annealing has been found to affect the properties of graphite/epoxy composites. The network epoxy studied was based on the chemistry of tetraglycidyl 4,4'-diamino-diphenyl methane (TGDDM) crosslinked by 4,4'-diamino-diphenyl sulfone (DDS). Differential scanning calorimetry, thermal mechanical analysis, and solid-state cross-polarized magic-angle-spinning nuclear magnetic resonance spectroscopy have been utilized in order to characterize this process of recovery towards thermodynamic equilibrium. The volume and enthalpy recovery as well as the 'thermoreversibility' aspects of the physical aging are discussed. This nonequilibrium and time-dependent behavior of network epoxies are considered in view of the increasingly wide applications of TGDDM-DDS epoxies as matrix materials of structural composites in the aerospace industry.

  9. Heterogeneous data fusion for brain tumor classification.

    PubMed

    Metsis, Vangelis; Huang, Heng; Andronesi, Ovidiu C; Makedon, Fillia; Tzika, Aria

    2012-10-01

    Current research in biomedical informatics involves analysis of multiple heterogeneous data sets. This includes patient demographics, clinical and pathology data, treatment history, patient outcomes as well as gene expression, DNA sequences and other information sources such as gene ontology. Analysis of these data sets could lead to better disease diagnosis, prognosis, treatment and drug discovery. In this report, we present a novel machine learning framework for brain tumor classification based on heterogeneous data fusion of metabolic and molecular datasets, including state-of-the-art high-resolution magic angle spinning (HRMAS) proton (1H) magnetic resonance spectroscopy and gene transcriptome profiling, obtained from intact brain tumor biopsies. Our experimental results show that our novel framework outperforms any analysis using individual dataset.

  10. Correlated insulator behaviour at half-filling in magic-angle graphene superlattices

    NASA Astrophysics Data System (ADS)

    Cao, Yuan; Fatemi, Valla; Demir, Ahmet; Fang, Shiang; Tomarken, Spencer L.; Luo, Jason Y.; Sanchez-Yamagishi, Javier D.; Watanabe, Kenji; Taniguchi, Takashi; Kaxiras, Efthimios; Ashoori, Ray C.; Jarillo-Herrero, Pablo

    2018-04-01

    A van der Waals heterostructure is a type of metamaterial that consists of vertically stacked two-dimensional building blocks held together by the van der Waals forces between the layers. This design means that the properties of van der Waals heterostructures can be engineered precisely, even more so than those of two-dimensional materials. One such property is the ‘twist’ angle between different layers in the heterostructure. This angle has a crucial role in the electronic properties of van der Waals heterostructures, but does not have a direct analogue in other types of heterostructure, such as semiconductors grown using molecular beam epitaxy. For small twist angles, the moiré pattern that is produced by the lattice misorientation between the two-dimensional layers creates long-range modulation of the stacking order. So far, studies of the effects of the twist angle in van der Waals heterostructures have concentrated mostly on heterostructures consisting of monolayer graphene on top of hexagonal boron nitride, which exhibit relatively weak interlayer interaction owing to the large bandgap in hexagonal boron nitride. Here we study a heterostructure consisting of bilayer graphene, in which the two graphene layers are twisted relative to each other by a certain angle. We show experimentally that, as predicted theoretically, when this angle is close to the ‘magic’ angle the electronic band structure near zero Fermi energy becomes flat, owing to strong interlayer coupling. These flat bands exhibit insulating states at half-filling, which are not expected in the absence of correlations between electrons. We show that these correlated states at half-filling are consistent with Mott-like insulator states, which can arise from electrons being localized in the superlattice that is induced by the moiré pattern. These properties of magic-angle-twisted bilayer graphene heterostructures suggest that these materials could be used to study other exotic many-body quantum phases in two dimensions in the absence of a magnetic field. The accessibility of the flat bands through electrical tunability and the bandwidth tunability through the twist angle could pave the way towards more exotic correlated systems, such as unconventional superconductors and quantum spin liquids.

  11. Beyond magic bullets: true innovation in health care.

    PubMed

    Narayan, Vaibhav A; Mohwinckel, Marco; Pisano, Gary; Yang, Michael; Manji, Husseini K

    2013-02-01

    The time has come to move beyond product-focused 'magic bullet' therapeutic development strategies towards models that can also incorporate devices, tools and services to provide integrated health-care solutions.

  12. Discerning the Location and Nature of Coke Deposition from Surface to Bulk of Spent Zeolite Catalysts

    NASA Astrophysics Data System (ADS)

    Devaraj, Arun; Vijayakumar, Murugesan; Bao, Jie; Guo, Mond F.; Derewinski, Miroslaw A.; Xu, Zhijie; Gray, Michel J.; Prodinger, Sebastian; Ramasamy, Karthikeyan K.

    2016-11-01

    The formation of carbonaceous deposits (coke) in zeolite pores during catalysis leads to temporary deactivation of catalyst, necessitating regeneration steps, affecting throughput, and resulting in partial permanent loss of catalytic efficiency. Yet, even to date, the coke molecule distribution is quite challenging to study with high spatial resolution from surface to bulk of the catalyst particles at a single particle level. To address this challenge we investigated the coke molecules in HZSM-5 catalyst after ethanol conversion treatment by a combination of C K-edge X-ray absorption spectroscopy (XAS), 13C Cross polarization-magic angle spinning nuclear magnetic resonance (CP-MAS NMR) spectroscopy, and atom probe tomography (APT). XAS and NMR highlighted the aromatic character of coke molecules. APT permitted the imaging of the spatial distribution of hydrocarbon molecules located within the pores of spent HZSM-5 catalyst from surface to bulk at a single particle level. 27Al NMR results and APT results indicated association of coke molecules with Al enriched regions within the spent HZSM-5 catalyst particles. The experimental results were additionally validated by a level-set-based APT field evaporation model. These results provide a new approach to investigate catalytic deactivation due to hydrocarbon coking or poisoning of zeolites at an unprecedented spatial resolution.

  13. Butterfly in the Quantum World; The story of the most fascinating quantum fractal

    NASA Astrophysics Data System (ADS)

    Satija, Indubala I.

    2016-08-01

    ``Butterfly in the Quantum World'' by Indu Satija, with contributions by Douglas Hofstadter, is the first book ever to tell the story of the ``Hofstadter butterfly'', a beautiful and fascinating graph lying at the heart of the quantum theory of matter. The butterfly came out of a simple-sounding question: What happens if you immerse a crystal in a magnetic field? What energies can the electrons take on? From 1930 onwards, physicists struggled to answer this question, until 1974, when graduate student Douglas Hofstadter discovered that the answer was a graph consisting of nothing but copies of itself nested down infinitely many times. This wild mathematical object caught the physics world totally by surprise, and it continues to mesmerize physicists and mathematicians today. The butterfly plot is intimately related to many other important phenomena in number theory and physics, including Apollonian gaskets, the Foucault pendulum, quasicrystals, the quantum Hall effect, and many more. Its story reflects the magic, the mystery, and the simplicity of the laws of nature, and Indu Satija, in a wonderfully personal style, relates this story, enriching it with a vast number of lively historical anecdotes, many photographs, beautiful visual images, and even poems, making her book a great feast, for the eyes, for the mind and for the soul.

  14. Discerning the Location and Nature of Coke Deposition from Surface to Bulk of Spent Zeolite Catalysts

    PubMed Central

    Devaraj, Arun; Vijayakumar, Murugesan; Bao, Jie; Guo, Mond F.; Derewinski, Miroslaw A.; Xu, Zhijie; Gray, Michel J.; Prodinger, Sebastian; Ramasamy, Karthikeyan K.

    2016-01-01

    The formation of carbonaceous deposits (coke) in zeolite pores during catalysis leads to temporary deactivation of catalyst, necessitating regeneration steps, affecting throughput, and resulting in partial permanent loss of catalytic efficiency. Yet, even to date, the coke molecule distribution is quite challenging to study with high spatial resolution from surface to bulk of the catalyst particles at a single particle level. To address this challenge we investigated the coke molecules in HZSM-5 catalyst after ethanol conversion treatment by a combination of C K-edge X-ray absorption spectroscopy (XAS), 13C Cross polarization-magic angle spinning nuclear magnetic resonance (CP-MAS NMR) spectroscopy, and atom probe tomography (APT). XAS and NMR highlighted the aromatic character of coke molecules. APT permitted the imaging of the spatial distribution of hydrocarbon molecules located within the pores of spent HZSM-5 catalyst from surface to bulk at a single particle level. 27Al NMR results and APT results indicated association of coke molecules with Al enriched regions within the spent HZSM-5 catalyst particles. The experimental results were additionally validated by a level-set–based APT field evaporation model. These results provide a new approach to investigate catalytic deactivation due to hydrocarbon coking or poisoning of zeolites at an unprecedented spatial resolution. PMID:27876869

  15. Application of modern tensor calculus to engineered domain structures. 1. Calculation of tensorial covariants.

    PubMed

    Kopský, Vojtech

    2006-03-01

    This article is a roadmap to a systematic calculation and tabulation of tensorial covariants for the point groups of material physics. The following are the essential steps in the described approach to tensor calculus. (i) An exact specification of the considered point groups by their embellished Hermann-Mauguin and Schoenflies symbols. (ii) Introduction of oriented Laue classes of magnetic point groups. (iii) An exact specification of matrix ireps (irreducible representations). (iv) Introduction of so-called typical (standard) bases and variables -- typical invariants, relative invariants or components of the typical covariants. (v) Introduction of Clebsch-Gordan products of the typical variables. (vi) Calculation of tensorial covariants of ascending ranks with consecutive use of tables of Clebsch-Gordan products. (vii) Opechowski's magic relations between tensorial decompositions. These steps are illustrated for groups of the tetragonal oriented Laue class D(4z) -- 4(z)2(x)2(xy) of magnetic point groups and for tensors up to fourth rank.

  16. Levitation forces of a bulk YBCO superconductor in gradient varying magnetic fields

    NASA Astrophysics Data System (ADS)

    Jiang, J.; Gong, Y. M.; Wang, G.; Zhou, D. J.; Zhao, L. F.; Zhang, Y.; Zhao, Y.

    2015-09-01

    The levitation forces of a bulk YBCO superconductor in gradient varying high and low magnetic fields generated from a superconducting magnet were investigated. The magnetic field intensity of the superconducting magnet was measured when the exciting current was 90 A. The magnetic field gradient and magnetic force field were both calculated. The YBCO bulk was cooled by liquid nitrogen in field-cooling (FC) and zero-field-cooling (ZFC) condition. The results showed that the levitation forces increased with increasing the magnetic field intensity. Moreover, the levitation forces were more dependent on magnetic field gradient and magnetic force field than magnetic field intensity.

  17. High magnetic field ohmically decoupled non-contact technology

    DOEpatents

    Wilgen, John [Oak Ridge, TN; Kisner, Roger [Knoxville, TN; Ludtka, Gerard [Oak Ridge, TN; Ludtka, Gail [Oak Ridge, TN; Jaramillo, Roger [Knoxville, TN

    2009-05-19

    Methods and apparatus are described for high magnetic field ohmically decoupled non-contact treatment of conductive materials in a high magnetic field. A method includes applying a high magnetic field to at least a portion of a conductive material; and applying an inductive magnetic field to at least a fraction of the conductive material to induce a surface current within the fraction of the conductive material, the surface current generating a substantially bi-directional force that defines a vibration. The high magnetic field and the inductive magnetic field are substantially confocal, the fraction of the conductive material is located within the portion of the conductive material and ohmic heating from the surface current is ohmically decoupled from the vibration. An apparatus includes a high magnetic field coil defining an applied high magnetic field; an inductive magnetic field coil coupled to the high magnetic field coil, the inductive magnetic field coil defining an applied inductive magnetic field; and a processing zone located within both the applied high magnetic field and the applied inductive magnetic field. The high magnetic field and the inductive magnetic field are substantially confocal, and ohmic heating of a conductive material located in the processing zone is ohmically decoupled from a vibration of the conductive material.

  18. Central depression in nuclear density and its consequences for the shell structure of superheavy nuclei

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Afanasjev, A.V.; Laboratory of Radiation Physics, Institute of Solid State Physics, University of Latvia, LV 2169 Salaspils, Miera str. 31; Frauendorf, S.

    The influence of the central depression in the density distribution of spherical superheavy nuclei on the shell structure is studied within the relativistic mean-field theory. A large depression leads to the shell gaps at the proton Z=120 and neutron N=172 numbers, whereas a flatter density distribution favors N=184 and leads to the appearance of a Z=126 shell gap and to the decrease of the size of the Z=120 shell gap. The correlations between the magic shell gaps and the magnitude of the central depression are discussed for relativistic and nonrelativistic mean field theories.

  19. Verdazyl-ribose: A new radical for solid-state dynamic nuclear polarization at high magnetic field

    NASA Astrophysics Data System (ADS)

    Thurber, Kent R.; Le, Thanh-Ngoc; Changcoco, Victor; Brook, David J. R.

    2018-04-01

    Solid-state dynamic nuclear polarization (DNP) using the cross-effect relies on radical pairs whose electron spin resonance (ESR) frequencies differ by the nuclear magnetic resonance (NMR) frequency. We measure the DNP provided by a new water-soluble verdazyl radical, verdazyl-ribose, under both magic-angle spinning (MAS) and static sample conditions at 9.4 T, and compare it to a nitroxide radical, 4-hydroxy-TEMPO. We find that verdazyl-ribose is an effective radical for cross-effect DNP, with the best relative results for a non-spinning sample. Under non-spinning conditions, verdazyl-ribose provides roughly 2× larger 13C cross-polarized (CP) NMR signal than the nitroxide, with similar polarization buildup times, at both 29 K and 76 K. With MAS at 7 kHz and 1.5 W microwave power, the verdazyl-ribose does not provide as much DNP as the nitroxide, with the verdazyl providing less NMR signal and a longer polarization buildup time. When the microwave power is decreased to 30 mW with 5 kHz MAS, the two types of radical are comparable, with the verdazyl-doped sample having a larger NMR signal which compensates for its longer polarization buildup time. We also present electron spin relaxation measurements at Q-band (1.2 T) and ESR lineshapes at 1.2 and 9.4 T. Most notably, the verdazyl radical has a longer T1e than the nitroxide (9.9 ms and 1.3 ms, respectively, at 50 K and 1.2 T). The verdazyl electron spin lineshape is significantly affected by the hyperfine coupling to four 14N nuclei, even at 9.4 T. We also describe 3000-spin calculations to illustrate the DNP potential of possible radical pairs: verdazyl-verdazyl, verdazyl-nitroxide, or nitroxide-nitroxide pairs. These calculations suggest that the verdazyl radical at 9.4 T has a narrower linewidth than optimal for cross-effect DNP using verdazyl-verdazyl pairs. Because of the hyperfine coupling contribution to the electron spin linewidth, this implies that DNP using the verdazyl radical would improve at lower magnetic field. Another conclusion from the calculations is that a verdazyl-nitroxide bi-radical would be expected to be slightly better for cross-effect DNP than the nitroxide-nitroxide bi-radicals commonly used now, assuming the same spin-spin coupling constants.

  20. Electric Field Feature of Moving Magnetic Field

    NASA Astrophysics Data System (ADS)

    Chen, You Jun

    2001-05-01

    A new fundamental relationship of electric field with magnetic field has been inferred from the fundamental experimental laws and theories of classical electromagnetics. It can be described as moving magnetic field has or gives electric feature. When a field with magnetic induction of B moves in the velocity of V, it will show electric field character, the electric field intensity E is E = B x V and the direction of E is in the direction of the vector B x V. It is improper to use the time-varying electromagnetics theories as the fundamental theory of the electromagnetics and group the electromagnetic field into static kind and time-varying kind for the static is relative to motional not only time-varying. The relationship of time variation of magnetic field induction or magnetic flux with electric field caused by magnetic field is fellowship not causality. Thus time-varying magnetic field can cause electric field is not a nature principle. Sometime the time variation of magnetic flux is equal to the negative electromotive force or the time variation of magnetic field induction is equal to the negative curl of electric field caused by magnetic field motion, but not always. And not all motion of magnetic field can cause time variation of magnetic field. Therefore Faraday-Lenz`s law can only be used as mathematics tool to calculate the quantity relation of the electricity with the magnetism in some case like the magnetic field moving in uniform medium. Faraday-Lenz`s law is unsuitable to be used in moving uniform magnetic field or there is magnetic shield. Key word: Motional magnetic field, Magnetic induction, Electric field intensity, Velocity, Faraday-Lenz’s law

  1. Quantification In Situ of Crystalline Cholesterol and Calcium Phosphate Hydroxyapatite in Human Atherosclerotic Plaques by Solid-State Magic Angle Spinning NMR

    PubMed Central

    Guo, Wen; Morrisett, Joel D.; DeBakey, Michael E.; Lawrie, Gerald M.; Hamilton, James A.

    2010-01-01

    Because of renewed interest in the progression, stabilization, and regression of atherosclerotic plaques, it has become important to develop methods for characterizing structural features of plaques in situ and noninvasively. We present a nondestructive method for ex vivo quantification of 2 solid-phase components of plaques: crystalline cholesterol and calcium phosphate salts. Magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectra of human carotid endarterectomy plaques revealed 13C resonances of crystalline cholesterol monohydrate and a 31P resonance of calcium phosphate hydroxyapatite (CPH). The spectra were obtained under conditions in which there was little or no interference from other chemical components and were suitable for quantification in situ of the crystalline cholesterol and CPH. Carotid atherosclerotic plaques showed a wide variation in their crystalline cholesterol content. The calculated molar ratio of liquid-crystalline cholesterol to phospholipid ranged from 1.1 to 1.7, demonstrating different capabilities of the phospholipids to reduce crystallization of cholesterol. The spectral properties of the phosphate groups in CPH in carotid plaques were identical to those of CPH in bone. 31P MAS NMR is a simple, rapid method for quantification of calcium phosphate salts in tissue without extraction and time-consuming chemical analysis. Crystalline phases in intact atherosclerotic plaques (ex vivo) can be quantified accurately by solid-state 13C and 31PMAS NMR spectroscopy. PMID:10845882

  2. The curious influence of timing on the magical experience evoked by conjuring tricks involving false transfer: decay of amodal object permanence?

    PubMed

    Beth, Tessa; Ekroll, Vebjørn

    2015-07-01

    In magic tricks involving false transfer, the conjurer typically creates the illusion of transferring a coin from one hand into the other, which is then closed into a fist, while in reality the coin is kept hidden in the first hand. The magical experience occurs when the closed fist of the second hand is opened and shown to be empty. According to professional magicians, the magical experience evoked by this kind of tricks becomes noticeably weaker when the time interval between the false transfer and the opening of the fist increases. This observation is surprising, given that neither the length of this interval nor any obvious factors associated with it can be expected to change the spectators' intellectual conviction regarding the true location of the coin. We performed a controlled psychological experiment and obtained results corroborating these informal observations. Increasing the temporal interval from 1 to 32 s led to an average reduction of the strength of the magical experience of 38%. We discuss potential explanations of this curious phenomenon in terms of object persistence, object files and temporal amodal completion.

  3. Distillation with Sublogarithmic Overhead

    NASA Astrophysics Data System (ADS)

    Hastings, Matthew B.; Haah, Jeongwan

    2018-02-01

    It has been conjectured that, for any distillation protocol for magic states for the T gate, the number of noisy input magic states required per output magic state at output error rate ɛ is Ω [log (1 /ɛ )] . We show that this conjecture is false. We find a family of quantum error correcting codes of parameters ⟦ ∑ i =w +1 m (m i ),∑ i =0 w (m i ),∑ i =w +1 r +1 (r +1 i )⟧ for any integers m >2 r , r >w ≥0 , by puncturing quantum Reed-Muller codes. When m >ν r , our code admits a transversal logical gate at the ν th level of Clifford hierarchy. In a distillation protocol for magic states at the level ν =3 (T gate), the ratio of input to output magic states is O (logγ(1 /ɛ )) , where γ =log (n /k )/log (d )<0.678 for some m , r , w . The smallest code in our family for which γ <1 is on ≈258 qubits.

  4. People Interview: The science behind the 'magic'

    NASA Astrophysics Data System (ADS)

    2010-01-01

    INTERVIEW The science behind the 'magic' Grand Illusions is a website dedicated to science-based phenomena, fun and games, and optical illusions. David Smith speaks to two of its key members—Hendrik Ball and Tim Rowett.

  5. Structural properties and magic structures in hydrogenated finite and infinite silicon nanowires

    NASA Astrophysics Data System (ADS)

    Zdetsis, A. D.; Koukaras, E. N.; Garoufalis, C. S.

    2007-11-01

    Unusual effects such as bending and "canting," related with the stability, have been identified by ab initio real-space calculations for hydrogenated silicon nanowires. We have examined in detail the electronic and structural properties of finite and infinite nanowires as a function of length (and width) and have developed stability and bending rules, demonstrating that "magic" wires do not bend. Reconstructed 2×1 nanowires are practically as stable as the magic ones. Our calculations are in good agreement with the experimental data of Ma et al. [Science 299, 1874 (2003).].

  6. Magic informationally complete POVMs with permutations

    NASA Astrophysics Data System (ADS)

    Planat, Michel; Gedik, Zafer

    2017-09-01

    Eigenstates of permutation gates are either stabilizer states (for gates in the Pauli group) or magic states, thus allowing universal quantum computation (Planat, Rukhsan-Ul-Haq 2017 Adv. Math. Phys. 2017, 5287862 (doi:10.1155/2017/5287862)). We show in this paper that a subset of such magic states, when acting on the generalized Pauli group, define (asymmetric) informationally complete POVMs. Such informationally complete POVMs, investigated in dimensions 2-12, exhibit simple finite geometries in their projector products and, for dimensions 4 and 8 and 9, relate to two-qubit, three-qubit and two-qutrit contextuality.

  7. Structure and Dynamics of Nonionic Surfactant Aggregates in Layered Materials.

    PubMed

    Guégan, Régis; Veron, Emmanuel; Le Forestier, Lydie; Ogawa, Makoto; Cadars, Sylvian

    2017-09-26

    The aggregation of surfactants on solid surfaces as they are adsorbed from solution is the basis of numerous technological applications such as colloidal stabilization, ore flotation, and floor cleaning. The understanding of both the structure and the dynamics of surfactant aggregates applies to the development of alternative ways of preparing hybrid layered materials. For this purpose, we study the adsorption of the triethylene glycol mono n-decyl ether (C 10 E 3 ) nonionic surfactant onto a synthetic montmorillonite (Mt), an aluminosilicate clay mineral for organoclay preparation with important applications in materials sciences, catalysis, wastewater treatment, or as drug delivery. The aggregation mechanisms follow those observed in an analogous natural Mt, with the condensation of C 10 E 3 in a bilayer arrangement once the surfactant self-assembles in a lamellar phase beyond the critical micelle concentration, underlining the importance of the surfactant state in solution. Solid-state 1 H nuclear magnetic resonance (NMR) at fast magic-angle spinning (MAS) and high magnetic field combined with 1 H- 13 C correlation experiments and different types of 13 C NMR experiments selectively probes mobile or rigid moieties of C 10 E 3 in three different aggregate organizations: (i) a lateral monolayer, (ii) a lateral bilayer, and (iii) a normal bilayer. High-resolution 1 H{ 27 Al} CP- 1 H- 1 H spin diffusion experiments shed light on the proximities and dynamics of the different fragments and fractions of the intercalated surfactant molecules with respect to the Mt surface. 23 Na and 1 H NMR measurements combined with complementary NMR data, at both molecular and nanometer scales, precisely pointed out the location of the C 10 E 3 ethylene oxide hydrophilic group in close contact with the Mt surface interacting through ion-dipole or van der Waals interactions.

  8. Intratumoral Agreement of High-Resolution Magic Angle Spinning Magnetic Resonance Spectroscopic Profiles in the Metabolic Characterization of Breast Cancer

    PubMed Central

    Park, Vivian Youngjean; Yoon, Dahye; Koo, Ja Seung; Kim, Eun-Kyung; Kim, Seung Il; Choi, Ji Soo; Park, Seho; Park, Hyung Seok; Kim, Suhkmann; Kim, Min Jung

    2016-01-01

    Abstract High-resolution magic angle spinning (HR-MAS) magnetic resonance (MR) spectroscopy data may serve as a biomarker for breast cancer, with only a small volume of tissue sample required for assessment. However, previous studies utilized only a single tissue sample from each patient. The aim of this study was to investigate whether intratumoral location and biospecimen type affected the metabolic characterization of breast cancer assessed by HR-MAS MR spectroscopy This prospective study was approved by the institutional review board and informed consent was obtained. Preoperative core-needle biopsies (CNBs), central, and peripheral surgical tumor specimens were prospectively collected under ultrasound (US) guidance in 31 patients with invasive breast cancer. Specimens were assessed with HR-MAS MR spectroscopy. The reliability of metabolite concentrations was evaluated and multivariate analysis was performed according to intratumoral location and biospecimen type. There was a moderate or higher agreement between the relative concentrations of 94.3% (33 of 35) of metabolites in the center and periphery, 80.0% (28 of 35) of metabolites in the CNB and central surgical specimens, and 82.9% (29 of 35) of metabolites between all 3 specimen types. However, there was no significant agreement between the concentrations of phosphocholine (PC) and phosphoethanolamine (PE) in the center and periphery. The concentrations of several metabolites (adipate, arginine, fumarate, glutamate, PC, and PE) had no significant agreement between the CNB and central surgical specimens. In conclusion, most HR-MAS MR spectroscopic data do not differ based on intratumoral location or biospecimen type. However, some metabolites may be affected by specimen-related variables, and caution is recommended in decision-making based solely on metabolite concentrations, particularly PC and PE. Further validation through future studies is needed for the clinical implementation of these biomarkers based on data from a single tissue sample. PMID:27082613

  9. Evaluation of toxicological effects induced by tributyltin in clam Ruditapes decussatus using high-resolution magic angle spinning nuclear magnetic resonance spectroscopy: Study of metabolic responses in heart tissue and detection of a novel metabolite.

    PubMed

    Hanana, H; Simon, G; Kervarec, N; Cérantola, S

    2014-01-01

    Tributyltin (TBT) is a highly toxic pollutant present in many aquatic ecosystems. Its toxicity in mollusks strongly affects their performance and survival. The main purpose of this study was to elucidate the mechanisms of TBT toxicity in clam Ruditapes decussatus by evaluating the metabolic responses of heart tissues, using high-resolution magic angle-spinning nuclear magnetic resonance (HRMAS NMR), after exposure to TBT (10 -9 , 10 -6 and 10 -4 M) during 24 h and 72 h. Results show that responses of clam heart tissue to TBT exposure are not dose dependent. Metabolic profile analyses indicated that TBT 10 -6 M, contrary to the two other doses tested, led to a significant depletion of taurine and betaine. Glycine levels decreased in all clam groups treated with the organotin. It is suggested that TBT abolished the cytoprotective effect of taurine, betaine and glycine thereby inducing cardiomyopathie. Moreover, results also showed that TBT induced increase in the level of alanine and succinate suggesting the occurrence of anaerobiosis particularly in clam group exposed to the highest dose of TBT. Taken together, these results demonstrate that TBT is a potential toxin with a variety of deleterious effects on clam and this organotin may affect different pathways depending to the used dose. The main finding of this study was the appearance of an original metabolite after TBT treatment likely N-glycine-N'-alanine. It is the first time that this molecule has been identified as a natural compound. Its exact role is unknown and remains to be elucidated. We suppose that its formation could play an important role in clam defense response by attenuating Ca 2+ dependent cell death induced by TBT. Therefore this compound could be a promising biomarker for TBT exposure.

  10. Studies of phospholipid hydration by high-resolution magic-angle spinning nuclear magnetic resonance.

    PubMed Central

    Zhou, Z; Sayer, B G; Hughes, D W; Stark, R E; Epand, R M

    1999-01-01

    A sample preparation method using spherical glass ampoules has been used to achieve 1.5-Hz resolution in 1H magic-angle spinning (MAS) nuclear magnetic resonance (NMR) spectra of aqueous multilamellar dispersions of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC), serving to differentiate between slowly exchanging interlamellar and bulk water and to reveal new molecular-level information about hydration phenomena in these model biological membranes. The average numbers of interlamellar water molecules in multilamellar vesicles (MLVs) of DOPC and POPC were found to be 37.5 +/- 1 and 37.2 +/- 1, respectively, at a spinning speed of 3 kHz. Even at speeds as high as 9 kHz, the number of interlamellar waters remained as high as 31, arguing against dehydration effects for DOPC and POPC. Both homonuclear and heteronuclear nuclear Overhauser enhancement spectroscopy (NOESY and HOESY) were used to establish the location of water near the headgroup of a PC bilayer. 1H NMR comparisons of DOPC with a lipid that can hydrogen bond (monomethyldioleoylphosphatidylethanolamine, MeDOPE) showed the following trends: 1) the interlamellar water resonance was shifted to lower frequency for DOPC but to higher frequency for MeDOPE, 2) the chemical shift variation with temperature for interlamellar water was less than that of bulk water for MeDOPE MLVs, 3) water exchange between the two lipids was rapid on the NMR time scale if they were mixed in the same bilayer, 4) water exchange was slow if they were present in separate MLVs, and 5) exchange between bulk and interlamellar water was found by two-dimensional exchange experiments to be slow, and the exchange rate should be less than 157 Hz. These results illustrate the utility of ultra-high-resolution 1H MAS NMR for determining the nature and extent of lipid hydration as well as the arrangement of nuclei at the membrane/water interface. PMID:9876150

  11. Very-high-energy gamma-ray observations of pulsar wind nebulae and cataclysmic variable stars with MAGIC and development of trigger systems for IACTs

    NASA Astrophysics Data System (ADS)

    Lopez-Coto, Ruben

    2015-07-01

    The history of astronomy is as ancient as the reach of our written records. All the human civilizations have been interested in the study and interpretation of the night sky and its objects and phenomena. These observations were performed with the naked eye until the beginning of the 17th century, when Galileo Galilei started to use an instrument recently developed called telescope. Since then, the range of accessible wavelengths has been increasing, with a burst in the 20th century with the developing of instruments to observe them: antennas (radio and submillimeter), telescopes (optical, IR) and satellites (UV, X-rays and soft gamma rays). The last wavelength range accessed was the Very-High-Energy (VHE) gamma rays. At this range fluxes are so low that it is not possible to use space-based instruments with typical collection areas of O(1) m2. We must resort to the imaging atmospheric Cherenkov technique, which is based on the detection of the flashes of Cherenkov light that VHE gamma rays produce when they interact with the Earth's atmosphere. The field is very young, with the first source discovered in 1989 by the pioneering Whipple telescope. It is very dynamic with more than 150 sources detected to date, most of them by MAGIC, HESS and VERITAS, that make up the current generation of instruments. Finally, the field is also very promising, with the preparation of a next generation of imaging atmospheric Cherenkov telescopes: CTA, that is expected to start full operation in 2020. The work presented in this thesis comprises my efforts to take the ground-based γ-ray astronomy one step forward. Part I of the thesis is an introduction to the non- thermal universe, the imaging atmospheric Cherenkov technique and the Imaging Atmospheric Cherenkov Telescopes (IACTs) MAGIC and CTA. Part II deals with several ways to reduce the trigger threshold of IACTs. This includes the simula- tion, characterization and test of an analog trigger especially designed to achieve the lowest possible energy threshold with the LSTs of CTA. Together with this work, the trigger of the MAGIC telescopes was improved. We have simulated, tested and commissioned a new concept of stereoscopic trigger. This new system, that uses the information of the position of the showers on each of the MAGIC cameras, is dubbed "Topo-trigger". The scientific fraction of the thesis deals with galactic sources observed with the MAGIC telescopes. In Part III, I talk about the analysis of the VHE γ-ray emission of Pulsar Wind Nebulae (PWNe): the discovery of VHE γ-ray emission from the puzzling PWN 3C 58, the likely remnant of the SN 1181 AD and the weakest PWN detected at VHE to date; the characterization of the VHE tail of the Crab nebula by observing it at the highest zenith angles; and the search for an additional inverse Compton component during the Crab nebula flares reported by Fermi-LAT in the synchrotron regime. Part IV is concerned with searches for VHE γ-ray emission of cataclysmic variable stars. I studied, on a multiwavelength context, the VHE γ-ray nature of the previously claimed pulsed γ-ray emission of the cataclysmic variable AE Aqr. I also performed observations of novae and a dwarf nova to pinpoint the ac- celeration mechanisms taking place in this kind of objects and to discover a putative hadronic component of the soft γ-ray emission. A conclusion chapter summarizes all the work performed and lists prospects related with the topics treated in this thesis.

  12. Detection of very high energy gamma-ray emission from the gravitationally lensed blazar QSO B0218+357 with the MAGIC telescopes

    NASA Astrophysics Data System (ADS)

    Ahnen, M. L.; Ansoldi, S.; Antonelli, L. A.; Antoranz, P.; Arcaro, C.; Babic, A.; Banerjee, B.; Bangale, P.; Barres de Almeida, U.; Barrio, J. A.; Becerra González, J.; Bednarek, W.; Bernardini, E.; Berti, A.; Biasuzzi, B.; Biland, A.; Blanch, O.; Bonnefoy, S.; Bonnoli, G.; Borracci, F.; Bretz, T.; Buson, S.; Carosi, A.; Chatterjee, A.; Clavero, R.; Colin, P.; Colombo, E.; Contreras, J. L.; Cortina, J.; Covino, S.; Da Vela, P.; Dazzi, F.; De Angelis, A.; De Lotto, B.; de Oña Wilhelmi, E.; Di Pierro, F.; Doert, M.; Domínguez, A.; Dominis Prester, D.; Dorner, D.; Doro, M.; Einecke, S.; Eisenacher Glawion, D.; Elsaesser, D.; Engelkemeier, M.; Fallah Ramazani, V.; Fernández-Barral, A.; Fidalgo, D.; Fonseca, M. V.; Font, L.; Frantzen, K.; Fruck, C.; Galindo, D.; García López, R. J.; Garczarczyk, M.; Garrido Terrats, D.; Gaug, M.; Giammaria, P.; Godinović, N.; Gora, D.; Guberman, D.; Hadasch, D.; Hahn, A.; Hayashida, M.; Herrera, J.; Hose, J.; Hrupec, D.; Hughes, G.; Idec, W.; Kodani, K.; Konno, Y.; Kubo, H.; Kushida, J.; La Barbera, A.; Lelas, D.; Lindfors, E.; Lombardi, S.; Longo, F.; López, M.; López-Coto, R.; Majumdar, P.; Makariev, M.; Mallot, K.; Maneva, G.; Manganaro, M.; Mannheim, K.; Maraschi, L.; Marcote, B.; Mariotti, M.; Martínez, M.; Mazin, D.; Menzel, U.; Miranda, J. M.; Mirzoyan, R.; Moralejo, A.; Moretti, E.; Nakajima, D.; Neustroev, V.; Niedzwiecki, A.; Nievas Rosillo, M.; Nilsson, K.; Nishijima, K.; Noda, K.; Nogués, L.; Paiano, S.; Palacio, J.; Palatiello, M.; Paneque, D.; Paoletti, R.; Paredes, J. M.; Paredes-Fortuny, X.; Pedaletti, G.; Peresano, M.; Perri, L.; Persic, M.; Poutanen, J.; Prada Moroni, P. G.; Prandini, E.; Puljak, I.; Garcia, J. R.; Reichardt, I.; Rhode, W.; Ribó, M.; Rico, J.; Saito, T.; Satalecka, K.; Schroeder, S.; Schweizer, T.; Shore, S. N.; Sillanpää, A.; Sitarek, J.; Snidaric, I.; Sobczynska, D.; Stamerra, A.; Strzys, M.; Surić, T.; Takalo, L.; Tavecchio, F.; Temnikov, P.; Terzić, T.; Tescaro, D.; Teshima, M.; Torres, D. F.; Toyama, T.; Treves, A.; Vanzo, G.; Verguilov, V.; Vovk, I.; Ward, J. E.; Will, M.; Wu, M. H.; Zanin, R.; Desiante, R.

    2016-11-01

    Context. QSO B0218+357 is a gravitationally lensed blazar located at a redshift of 0.944. The gravitational lensing splits the emitted radiation into two components that are spatially indistinguishable by gamma-ray instruments, but separated by a 10-12 day delay. In July 2014, QSO B0218+357 experienced a violent flare observed by the Fermi-LAT and followed by the MAGIC telescopes. Aims: The spectral energy distribution of QSO B0218+357 can give information on the energetics of z 1 very high energy gamma-ray sources. Moreover the gamma-ray emission can also be used as a probe of the extragalactic background light at z 1. Methods: MAGIC performed observations of QSO B0218+357 during the expected arrival time of the delayed component of the emission. The MAGIC and Fermi-LAT observations were accompanied by quasi-simultaneous optical data from the KVA telescope and X-ray observations by Swift-XRT. We construct a multiwavelength spectral energy distribution of QSO B0218+357 and use it to model the source. The GeV and sub-TeV data obtained by Fermi-LAT and MAGIC are used to set constraints on the extragalactic background light. Results: Very high energy gamma-ray emission was detected from the direction of QSO B0218+357 by the MAGIC telescopes during the expected time of arrival of the trailing component of the flare, making it the farthest very high energy gamma-ray source detected to date. The observed emission spans the energy range from 65 to 175 GeV. The combined MAGIC and Fermi-LAT spectral energy distribution of QSO B0218+357 is consistent with current extragalactic background light models. The broadband emission can be modeled in the framework of a two-zone external Compton scenario, where the GeV emission comes from an emission region in the jet, located outside the broad line region.

  13. Detection of very high energy gamma-ray emission from the gravitationally lensed blazar QSO B0218+357 with the MAGIC telescopes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ahnen, M. L.; Ansoldi, S.; Antonelli, L. A.

    QSO B0218+357 is a gravitationally lensed blazar located at a redshift of 0.944. The gravitational lensing splits the emitted radiation into two components that are spatially indistinguishable by gamma-ray instruments, but separated by a 10–12 day delay. In July 2014, QSO B0218+357 experienced a violent flare observed by the Fermi-LAT and followed by the MAGIC telescopes. The spectral energy distribution of QSO B0218+357 can give information on the energetics of z ~ 1 very high energy gamma-ray sources. Furthermore, the gamma-ray emission can also be used as a probe of the extragalactic background light at z ~ 1. MAGIC performedmore » observations of QSO B0218+357 during the expected arrival time of the delayed component of the emission. The MAGIC and Fermi-LAT observations were accompanied by quasi-simultaneous optical data from the KVA telescope and X-ray observations by Swift-XRT. We construct a multiwavelength spectral energy distribution of QSO B0218+357 and use it to model the source. The GeV and sub-TeV data obtained by Fermi-LAT and MAGIC are used to set constraints on the extragalactic background light. We detected very high energy gamma-ray emission from the direction of QSO B0218+357 by the MAGIC telescopes during the expected time of arrival of the trailing component of the flare, making it the farthest very high energy gamma-ray source detected to date. We also observed emission spans the energy range from 65 to 175 GeV. The combined MAGIC and Fermi-LAT spectral energy distribution of QSO B0218+357 is consistent with current extragalactic background light models. The broadband emission can be modeled in the framework of a two-zone external Compton scenario, where the GeV emission comes from an emission region in the jet, located outside the broad line region.« less

  14. Detection of very high energy gamma-ray emission from the gravitationally lensed blazar QSO B0218+357 with the MAGIC telescopes

    DOE PAGES

    Ahnen, M. L.; Ansoldi, S.; Antonelli, L. A.; ...

    2016-11-04

    QSO B0218+357 is a gravitationally lensed blazar located at a redshift of 0.944. The gravitational lensing splits the emitted radiation into two components that are spatially indistinguishable by gamma-ray instruments, but separated by a 10–12 day delay. In July 2014, QSO B0218+357 experienced a violent flare observed by the Fermi-LAT and followed by the MAGIC telescopes. The spectral energy distribution of QSO B0218+357 can give information on the energetics of z ~ 1 very high energy gamma-ray sources. Furthermore, the gamma-ray emission can also be used as a probe of the extragalactic background light at z ~ 1. MAGIC performedmore » observations of QSO B0218+357 during the expected arrival time of the delayed component of the emission. The MAGIC and Fermi-LAT observations were accompanied by quasi-simultaneous optical data from the KVA telescope and X-ray observations by Swift-XRT. We construct a multiwavelength spectral energy distribution of QSO B0218+357 and use it to model the source. The GeV and sub-TeV data obtained by Fermi-LAT and MAGIC are used to set constraints on the extragalactic background light. We detected very high energy gamma-ray emission from the direction of QSO B0218+357 by the MAGIC telescopes during the expected time of arrival of the trailing component of the flare, making it the farthest very high energy gamma-ray source detected to date. We also observed emission spans the energy range from 65 to 175 GeV. The combined MAGIC and Fermi-LAT spectral energy distribution of QSO B0218+357 is consistent with current extragalactic background light models. The broadband emission can be modeled in the framework of a two-zone external Compton scenario, where the GeV emission comes from an emission region in the jet, located outside the broad line region.« less

  15. Magic While They are Young

    ERIC Educational Resources Information Center

    Cox, Anne Mae

    1974-01-01

    Magic squares are used both as a vehicle for arithmetic drill and the development of mathematical concepts for second-grade students. By searching for patterns within the squares, additional number concepts are developed along with the concept of symmetry. (JP)

  16. Clinical toxicology of ‘magic mushroom’ ingestion

    PubMed Central

    Peden, N. R.; Macaulay, K. E. C.; Bissett, Ann F.; Crooks, J.; Pelosi, A. J.

    1981-01-01

    The clinical features are reported in 27 cases of ‘magic mushroom’ ingestion. Mydriasis and hyperreflexia were common as were disorders of perception and affect. Psilocybe semilanceata appears to have been the species of fungus involved. PMID:7199140

  17. Thawing Out Some Magic

    ERIC Educational Resources Information Center

    Hippler, Arthur E.

    1975-01-01

    Psychiatrists have learned that delivering mental health services in a culture long dominated by magical thinking is not easy. Article discussed the problem of bringing the Eskimo into the care of the Alaska Psychiatric Institute and contemporary society. (Editor/RK)

  18. Pulsar observations with the MAGIC telescopes

    NASA Astrophysics Data System (ADS)

    Fidalgo, David

    2016-07-01

    The vast majority of spectra of gamma-ray pulsars exhibit an exponential cut-off at a few GeV, as seen by the Large Area Telescope (LAT) on board of the Fermi satellite. Due to this cut-off, current Imaging Atmospheric Cherenkov Telescopes (IACTs) with an energy threshold as low as 30 GeV, struggle to detect pulsars. So far, emission above 50 GeV has been confirmed only for the Crab and Vela pulsars. In the case of the former, the spectrum even extends up to about 1 TeV firmly revealing a second emission component. To further understand the emission mechanism of gamma-ray pulsars, the MAGIC collaboration continues the search of pulsars above 50 GeV. In this talk we report on recent results on the Crab and Geminga Pulsar obtained with the MAGIC telescopes, including the analysis of data taken with a new trigger system lowering the energy threshold of the MAGIC telescopes.

  19. Children's discrimination of fantastic vs. realistic visual displays after watching a film with magical content.

    PubMed

    Subbotsky, Eugene; Slater, Elizabeth

    2011-04-01

    Six- and nine-yr.-old children (n=28 of each) were divided into equal experimental and control groups. The experimental groups were shown a film with a magical theme, and the control groups were shown a film with a nonmagical theme. All groups then were presented with a choice task requiring them to discriminate between ordinary and fantastic visual displays on a computer screen. Statistical analyses indicated that mean scores for correctly identifying the ordinary and fantastic displays were significantly different between experimental and control groups. The children in the experimental groups who watched the magical film had significantly higher scores on correct identifications than children in the control groups who watched the nonmagical film for both age groups. The results suggest that watching films with a magical theme might enhance children's sensitivity toward the fantasy/reality distinction.

  20. Limits to dark matter annihilation cross-section from a combined analysis of MAGIC and Fermi-LAT observations of dwarf satellite galaxies

    NASA Astrophysics Data System (ADS)

    MAGIC Collaboration; Ahnen, M. L.; Ansoldi, S.; Antonelli, L. A.; Antoranz, P.; Babic, A.; Banerjee, B.; Bangale, P.; Barres de Almeida, U.; Barrio, J. A.; Becerra González, J.; Bednarek, W.; Bernardini, E.; Biasuzzi, B.; Biland, A.; Blanch, O.; Bonnefoy, S.; Bonnoli, G.; Borracci, F.; Bretz, T.; Carmona, E.; Carosi, A.; Chatterjee, A.; Clavero, R.; Colin, P.; Colombo, E.; Contreras, J. L.; Cortina, J.; Covino, S.; Da Vela, P.; Dazzi, F.; De Angelis, A.; De Lotto, B.; de Oña Wilhelmi, E.; Delgado Mendez, C.; Di Pierro, F.; Dominis Prester, D.; Dorner, D.; Doro, M.; Einecke, S.; Eisenacher Glawion, D.; Elsaesser, D.; Fernández-Barral, A.; Fidalgo, D.; Fonseca, M. V.; Font, L.; Frantzen, K.; Fruck, C.; Galindo, D.; García López, R. J.; Garczarczyk, M.; Garrido Terrats, D.; Gaug, M.; Giammaria, P.; Godinović, N.; González Muñoz,; A.; Guberman, D.; Hahn, A.; Hanabata, Y.; Hayashida, M.; Herrera, J.; Hose, J.; Hrupec, D.; Hughes, G.; Idec, W.; Kodani, K.; Konno, Y.; Kubo, H.; Kushida, J.; La Barbera, A.; Lelas, D.; Lindfors, E.; Lombardi, S.; Longo, F.; López-Coto, M. López R.; López-Oramas, A.; Lorenz, E.; Majumdar, P.; Makariev, M.; Mallot, K.; Maneva, G.; Manganaro, M.; Mannheim, K.; Maraschi, L.; Marcote, B.; Mariotti, M.; Martínez, M.; Mazin, D.; Menzel, U.; Miranda, J. M.; Mirzoyan, R.; Moralejo, A.; Moretti, E.; Nakajima, D.; Neustroev, V.; Niedzwiecki, A.; Nievas Rosillo, M.; Nilsson, K.; Nishijima, K.; Noda, K.; Orito, R.; Overkemping, A.; Paiano, S.; Palacio, J.; Palatiello, M.; Paneque, D.; Paoletti, R.; Paredes, J. M.; Paredes-Fortuny, X.; Persic, M.; Poutanen, J.; Prada Moroni, P. G.; Prandini, E.; Puljak, I.; Rhode, W.; Ribó, M.; Rico, J.; Rodriguez Garcia, J.; Saito, T.; Satalecka, K.; Schultz, C.; Schweizer, T.; Shore, S. N.; Sillanpää, A.; Sitarek, J.; Snidaric, I.; Sobczynska, D.; Stamerra, A.; Steinbring, T.; Strzys, M.; Takalo, L.; Takami, H.; Tavecchio, F.; Temnikov, P.; Terzić, T.; Tescaro, D.; Teshima, M.; Thaele, J.; Torres, D. F.; Toyama, T.; Treves, A.; Verguilov, V.; Vovk, I.; Ward, J. E.; Will, M.; Wup, M. H.; Zanins, R.; Aleksić, J.; Wood, M.; Anderson, B.; Bloom, E. D.; Cohen-Tanugi, J.; Drlica-Wagner, A.; Mazziotta, M. N.; Sánchez-Condeai, M.; Strigarian, L.

    2016-02-01

    We present the first joint analysis of gamma-ray data from the MAGIC Cherenkov telescopes and the Fermi Large Area Telescope (LAT) to search for gamma-ray signals from dark matter annihilation in dwarf satellite galaxies. We combine 158 hours of Segue 1 observations with MAGIC with 6-year observations of 15 dwarf satellite galaxies by the Fermi-LAT. We obtain limits on the annihilation cross-section for dark matter particle masses between 10 GeV and 100 TeV—the widest mass range ever explored by a single gamma-ray analysis. These limits improve on previously published Fermi-LAT and MAGIC results by up to a factor of two at certain masses. Our new inclusive analysis approach is completely generic and can be used to perform a global, sensitivity-optimized dark matter search by combining data from present and future gamma-ray and neutrino detectors.

  1. Rediscovery and Exploration of Magic Mountain, Explorer Ridge, NE Pacific

    NASA Astrophysics Data System (ADS)

    Embley, R. W.

    2002-12-01

    A two-part exploration program at Explorer Ridge, the northernmost spreading segment of the NE Pacific spreading centers, was conducted in two phases during June to August of 2002. A robust hydrothermal system (Magic Mountain) was found in this area in the early 1980s by the Canadian PISCES IV submersible, but its dimensions and geologic relationships were not well determined due to limited dives and poor navigation. The first part of the 2002 exploration program utilized an EM300 multibeam sonar on T. G. Thompson, the autonomous vehicle ABE, and a CTD/rosette system to map the seafloor and conduct hydrothermal plume surveys. While ABE conducted detailed surveys in the area where the most intense hydrothermal plume was found on the initial CTD survey, the T. G. Thompson conducted additional multibeam surveys, CTD casts and CTD tow-yos on the other second order segments up to 60 km away. This increased the efficiency of the expedition by at least 30%. After 12 days on site, a multibeam map was completed of the entire segment, the spatial distribution and character of the hydrothermal plumes were mapped out and a section of seafloor measuring 2 x 5.5 km was mapped in detail with ABE. The ABE used two sonar systems, a previously proven Imagenex pencil beam sonar, and, for the first time, a multibeam sonar (SM2000). In addition to the high-resolution bathymetry (1 m grid-cell size resolution for the SM2000), ABE collected temperature, optical backscatter, eH redox potential, and magnetic field data. Using the CTD and ABE data, a major hydrothermal system was easily located on the seafloor during the second part of the exploration program using the ROPOS remotely operated vehicle. The Magic Mountain hydrothermal system is located almost entirely on the eastern constructional shoulder of the ridge eastward of the rim of the eastern boundary fault of the axial valley. This is in contrast to most other hydrothermal systems on intermediate rate spreading ridges, which are either centered within the neovolcanic zone or associated with a boundary fault. The active venting occurs over at least 400 m along axis and is mostly concentrated in clusters of high temperature chimneys, each about 50 m in diameter. Two of these clusters have a basal sulfide mound. There is obvious structural control of many of the vents - many lie along or in line with distinct fissures or small faults and the entire field appears to have developed within a shallow graben formed on the ridge flank. Most of the chimneys consist of relatively friable sulfates (barite/anhydrite) that vent clear fluid at up to about 290°C. Several larger active chimneys consist primarily of sulfide minerals that emit gray smoke with temperatures as high as 312§ C. Biologic communities were primarily associated with the more stable sulfide structures. The mixture of proven technology used from a capable surface vessel during the 2002 Explorer Ridge program, including a cutting edge deep AUV and a large ROV, provided the tools to explore a little-known site at a full range of scales in a short amount of time and collect invaluable samples for research. These initial data sets from the 2002 exploration program set the stage for more detailed studies of this unique hydrothermal system in the future.

  2. Effects of Cd vacancies and unconventional spin dynamics in the Dirac semimetal Cd3As2

    NASA Astrophysics Data System (ADS)

    Koumoulis, Dimitrios; Taylor, Robert E.; McCormick, Jeffrey; Ertas, Yavuz N.; Pan, Lei; Che, Xiaoyu; Wang, Kang L.; Bouchard, Louis-S.

    2017-08-01

    Cd3As2 is a Dirac semimetal that is a 3D analog of graphene. We investigated the local structure and nuclear-spin dynamics in Cd3As2 via 113Cd NMR. The wideline spectrum of the static sample at 295 K is asymmetric and its features are well described by a two-site model with the shielding parameters extracted via Herzfeld-Berger analysis of the magic-angle spinning spectrum. Surprisingly, the 113Cd spin-lattice relaxation time (T1) is extremely long (T1 = 95 s at 295 K), in stark contrast to conductors and the effects of native defects upon semiconductors; but it is similar to that of 13C in graphene (T1 = 110 s). The temperature dependence of 1/T1 revealed a complex bipartite mechanism that included a T2 power-law behavior below 330 K and a thermally activated process above 330 K. In the high-temperature regime, the Arrhenius behavior is consistent with a field-dependent Cd atomic hopping relaxation process. At low temperatures, a T2 behavior consistent with a spin-1/2 Raman-like process provides evidence of a time-dependent spin-rotation magnetic field caused by angular oscillations of internuclear vectors due to lattice vibrations. The observed mechanism does not conform to the conventional two-band model of semimetals, but is instead closer to a mechanism observed in high-Z element ionic solids with large magnetorotation constant [A. J. Vega et al., Phys. Rev. B 74, 214420 (2006)].

  3. Initial experiments with gel-water: towards MRI-linac dosimetry and imaging.

    PubMed

    Alnaghy, Sarah J; Gargett, Maegan; Liney, Gary; Petasecca, Marco; Begg, Jarrad; Espinoza, Anthony; Newall, Matthew K; Duncan, Mitchell; Holloway, Lois; Lerch, Michael L F; Lazea, Mircea; Rosenfeld, Anatoly B; Metcalfe, Peter

    2016-12-01

    Tracking the position of a moving radiation detector in time and space during data acquisition can replicate 4D image-guided radiotherapy (4DIGRT). Magnetic resonance imaging (MRI)-linacs need MRI-visible detectors to achieve this, however, imaging solid phantoms is an issue. Hence, gel-water, a material that provides signal for MRI-visibility, and which will in future work, replace solid water for an MRI-linac 4DIGRT quality assurance tool, is discussed. MR and CT images of gel-water were acquired for visualisation and electron density verification. Characterisation of gel-water at 0 T was compared to Gammex-RMI solid water, using MagicPlate-512 (M512) and RMI Attix chamber; this included percentage depth dose, tissue-phantom ratio (TPR 20/10 ), tissue-maximum ratio (TMR), profiles, output factors, and a gamma analysis to investigate field penumbral differences. MR images of a non-powered detector in gel-water demonstrated detector visualisation. The CT-determined gel-water electron density agreed with the calculated value of 1.01. Gel-water depth dose data demonstrated a maximum deviation of 0.7% from solid water for M512 and 2.4% for the Attix chamber, and by 2.1% for TPR 20/10 and 1.0% for TMR. FWHM and output factor differences between materials were ≤0.3 and ≤1.4%. M512 data passed gamma analysis with 100% within 2%, 2 mm tolerance for multileaf collimator defined fields. Gel-water was shown to be tissue-equivalent for dosimetry and a feasible option to replace solid water.

  4. NASA Tech Briefs, September 2008

    NASA Technical Reports Server (NTRS)

    2008-01-01

    Topics covered include: Nanotip Carpets as Antireflection Surfaces; Nano-Engineered Catalysts for Direct Methanol Fuel Cells; Capillography of Mats of Nanofibers; Directed Growth of Carbon Nanotubes Across Gaps; High-Voltage, Asymmetric-Waveform Generator; Magic-T Junction Using Microstrip/Slotline Transitions; On-Wafer Measurement of a Silicon-Based CMOS VCO at 324 GHz; Group-III Nitride Field Emitters; HEMT Amplifiers and Equipment for their On-Wafer Testing; Thermal Spray Formation of Polymer Coatings; Improved Gas Filling and Sealing of an HC-PCF; Making More-Complex Molecules Using Superthermal Atom/Molecule Collisions; Nematic Cells for Digital Light Deflection; Improved Silica Aerogel Composite Materials; Microgravity, Mesh-Crawling Legged Robots; Advanced Active-Magnetic-Bearing Thrust- Measurement System; Thermally Actuated Hydraulic Pumps; A New, Highly Improved Two-Cycle Engine; Flexible Structural-Health-Monitoring Sheets; Alignment Pins for Assembling and Disassembling Structures; Purifying Nucleic Acids from Samples of Extremely Low Biomass; Adjustable-Viewing-Angle Endoscopic Tool for Skull Base and Brain Surgery; UV-Resistant Non-Spore-Forming Bacteria From Spacecraft-Assembly Facilities; Hard-X-Ray/Soft-Gamma-Ray Imaging Sensor Assembly for Astronomy; Simplified Modeling of Oxidation of Hydrocarbons; Near-Field Spectroscopy with Nanoparticles Deposited by AFM; Light Collimator and Monitor for a Spectroradiometer; Hyperspectral Fluorescence and Reflectance Imaging Instrument; Improving the Optical Quality Factor of the WGM Resonator; Ultra-Stable Beacon Source for Laboratory Testing of Optical Tracking; Transmissive Diffractive Optical Element Solar Concentrators; Delaying Trains of Short Light Pulses in WGM Resonators; Toward Better Modeling of Supercritical Turbulent Mixing; JPEG 2000 Encoding with Perceptual Distortion Control; Intelligent Integrated Health Management for a System of Systems; Delay Banking for Managing Air Traffic; and Spline-Based Smoothing of Airfoil Curvatures.

  5. Magnetizing technique for permanent magnets by intense static fields generated by HTS bulk magnets: Numerical Analysis

    NASA Astrophysics Data System (ADS)

    N. Kawasaki; Oka, T.; Fukui, S.; Ogawa, J.; Sato, T.; Terasawa, T.; Itoh, Y.

    A demagnetized Nd-Fe-B permanent magnet was scanned in the strong magnetic field space just above the magnetic pole containing a HTS bulk magnet which generates the magnetic field 3.4 T. The magnet sample was subsequently found to be fully magnetized in the open space of the static magnetic fields. The finite element method was carried out for the static field magnetization of a permanent magnet using a HTS bulk magnet. Previously, our research group experimentally demonstrated the possibility of full magnetization of rare earth permanent magnets with high-performance magnetic properties with use of the static field of HTS bulk magnets. In the present study, however, we succeeded for the first time in visualizing the behavior of the magnetizing field of the bulk magnet during the magnetization process and the shape of the magnetic field inside the body being magnetized. By applying this kind of numerical analysis to the magnetization for planned motor rotors which incorporate rare-earth permanent magnets, we hope to study the fully magnetized regions for the new magnetizing method using bulk magnets and to give motor designing a high degree of freedom.

  6. Venus, the goddess of fertility, numerologically 15 in Babylon and the origin of the Chinese system of 8 designs, called Pa-Kua.

    PubMed

    Mahdihassan, S

    1987-01-01

    In Babylonia, numerology was invented and Venus, as the goddess of fertility, was first depicted as a 6-cornered star. But, numerologically she was designated 15. As a 6-cornered star, its make-up shows two opposite triangles interpenetrated. This was changed to two squares fused into one where geometrically the shape became a square. It created 9 cells which were so numbered that the numbers counted in any row gave the sum 15. Venus thus became a Magic Square of 15. Geometrically it was a Magic Square, but numerologically it was 15. In the make-up the squares were two and opposites. As goddess of fertility she especially helped the pregnant to an easy delivery. Some 8 variants of the Magic Square, with different arrangements of numbers, represented 4 cosmic elements and 4 cosmic qualities. The Magic Squares, which represented elements, had the numbers 1, 3, 5 and 8 near one another forming a miniature square by themselves. A Magic Square representing a quality did not have the numbers 1, 3, 5 and 8, as a consolidated unit. This explains the importance of the numbers 1, 3, 5 and 8, a mystery which had remained unsolved. Venus was also the star of copper. When copper technology migrated from Babylon to China, the occult science associated with Venus also reached China. Here the 8 Magic Squares were translated into a system of whole and broken lines, called Pa-Kua, meaning 8 designs.(ABSTRACT TRUNCATED AT 250 WORDS)

  7. A comparison of various algorithms to extract Magic Formula tyre model coefficients for vehicle dynamics simulations

    NASA Astrophysics Data System (ADS)

    Vijay Alagappan, A.; Narasimha Rao, K. V.; Krishna Kumar, R.

    2015-02-01

    Tyre models are a prerequisite for any vehicle dynamics simulation. Tyre models range from the simplest mathematical models that consider only the cornering stiffness to a complex set of formulae. Among all the steady-state tyre models that are in use today, the Magic Formula tyre model is unique and most popular. Though the Magic Formula tyre model is widely used, obtaining the model coefficients from either the experimental or the simulation data is not straightforward due to its nonlinear nature and the presence of a large number of coefficients. A common procedure used for this extraction is the least-squares minimisation that requires considerable experience for initial guesses. Various researchers have tried different algorithms, namely, gradient and Newton-based methods, differential evolution, artificial neural networks, etc. The issues involved in all these algorithms are setting bounds or constraints, sensitivity of the parameters, the features of the input data such as the number of points, noisy data, experimental procedure used such as slip angle sweep or tyre measurement (TIME) procedure, etc. The extracted Magic Formula coefficients are affected by these variants. This paper highlights the issues that are commonly encountered in obtaining these coefficients with different algorithms, namely, least-squares minimisation using trust region algorithms, Nelder-Mead simplex, pattern search, differential evolution, particle swarm optimisation, cuckoo search, etc. A key observation is that not all the algorithms give the same Magic Formula coefficients for a given data. The nature of the input data and the type of the algorithm decide the set of the Magic Formula tyre model coefficients.

  8. A tale of two morphs: modeling pollen transfer, magic traits, and reproductive isolation in parapatry.

    PubMed

    Haller, Benjamin C; de Vos, Jurriaan M; Keller, Barbara; Hendry, Andrew P; Conti, Elena

    2014-01-01

    The evolution of the flower is commonly thought to have spurred angiosperm diversification. Similarly, particular floral traits might have promoted diversification within specific angiosperm clades. We hypothesize that traits promoting the precise positional transfer of pollen between flowers might promote diversification. In particular, precise pollen transfer might produce partial reproductive isolation that facilitates adaptive divergence between parapatric populations differing in their reproductive-organ positions. We investigate this hypothesis with an individual-based model of pollen transfer dynamics associated with heterostyly, a floral syndrome that depends on precise pollen transfer. Our model shows that precise pollen transfer can cause sexual selection leading to divergence in reproductive-organ positions between populations served by different pollinators, pleiotropically causing an increase in reproductive isolation through a "magic trait" mechanism. Furthermore, this increased reproductive isolation facilitates adaptive divergence between the populations in an unlinked, ecologically selected trait. In a different pollination scenario, however, precise pollen transfer causes a decrease in adaptive divergence by promoting asymmetric gene flow. Our results highlight the idea that magic traits are not "magic" in isolation; in particular, the effect size of magic traits in speciation depends on the external environment, and also on other traits that modify the strength of the magic trait's influence on non-random mating. Overall, we show that the evolutionary consequences of pollen transfer dynamics can depend strongly on the available pollinator fauna and on the morphological fit between flowers and pollinators. Furthermore, our results illustrate the potential importance of even weak reproductive isolating barriers in facilitating adaptive divergence.

  9. Magic and the aesthetic illusion.

    PubMed

    Balter, Leon

    2002-01-01

    The aesthetic illusion is the subjective experience that the content of a work of art is reality. It has an intrinsic relation to magic, an intrapsychic maneuver oriented toward modification and control of the extraspyschic world, principally through ego functioning. Magic is ontogenetically and culturally archaic, expresses the omnipotence inherent in primary narcissism, and operates according to the logic of the primary process. Magic is a constituent of all ego functioning, usually latent in later development. It may persist as an archaic feature or may be evoked regressively in global or circumscribed ways. It causes a general disinhibition of instincts and impulses attended by a sense of confidence, exhiliration, and exuberance. The aesthetic illusion is a combination of illusions: (1) that the daydream embodied by the work of art is the beholder's own, the artist being ignored, and (2) that the artistically described protagonist is a real person with a real "world." The first illusion arises through the beholder's emotional-instinctual gratification from his or her own fantasy-memory constellations; the second comes about because the beholder, by taking the protagonist as proxy, mobilizes the subjective experience of the imaginary protagonist's "reality." The first illusion is necessary for the second to take place; the second establishes the aesthetic illusion proper. Both illusions are instances of magic. Accordingly, the aesthetic illusion is accompanied by a heady experience of excitement and euphoria. The relation among the aesthetic illusion, magic, and enthusiasm is illustrated by an analytic case, J. D. Salinger's "The Laughing Man," Woody Allen's Play It Again, Sam, Don Quixote, and the medieval Cult of the Saints.

  10. Numerical Calculation of Non-uniform Magnetization Using Experimental Magnetic Field Data

    NASA Astrophysics Data System (ADS)

    Jhun, Bukyoung; Jhun, Youngseok; Kim, Seung-wook; Han, JungHyun

    2018-05-01

    A relation between the distance from the surface of a magnet and the number of cells required for a numerical calculation in order to secure the error below a certain threshold is derived. We also developed a method to obtain the magnetization at each part of the magnet from the experimentally measured magnetic field. This method is applied to three magnets with distinct patterns on magnetic-field-viewing film. Each magnet showed a unique pattern of magnetization. We found that the magnet that shows symmetric magnetization on the magnetic-field-viewing film is not uniformly magnetized. This method can be useful comparing the magnetization between magnets that yield typical magnetic field and those that yield atypical magnetic field.

  11. Rotatable Small Permanent Magnet Array for Ultra-Low Field Nuclear Magnetic Resonance Instrumentation: A Concept Study.

    PubMed

    Vogel, Michael W; Giorni, Andrea; Vegh, Viktor; Pellicer-Guridi, Ruben; Reutens, David C

    2016-01-01

    We studied the feasibility of generating the variable magnetic fields required for ultra-low field nuclear magnetic resonance relaxometry with dynamically adjustable permanent magnets. Our motivation was to substitute traditional electromagnets by distributed permanent magnets, increasing system portability. The finite element method (COMSOL®) was employed for the numerical study of a small permanent magnet array to calculate achievable magnetic field strength, homogeneity, switching time and magnetic forces. A manually operated prototype was simulated and constructed to validate the numerical approach and to verify the generated magnetic field. A concentric small permanent magnet array can be used to generate strong sample pre-polarisation and variable measurement fields for ultra-low field relaxometry via simple prescribed magnet rotations. Using the array, it is possible to achieve a pre-polarisation field strength above 100 mT and variable measurement fields ranging from 20-50 μT with 200 ppm absolute field homogeneity within a field-of-view of 5 x 5 x 5 cubic centimetres. A dynamic small permanent magnet array can generate multiple highly homogeneous magnetic fields required in ultra-low field nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) instruments. This design can significantly reduce the volume and energy requirements of traditional systems based on electromagnets, improving portability considerably.

  12. Apparatus and method for magnetically processing a specimen

    DOEpatents

    Ludtka, Gerard M; Ludtka, Gail M; Wilgen, John B; Kisner, Roger A; Jaramillo, Roger A

    2013-09-03

    An apparatus for magnetically processing a specimen that couples high field strength magnetic fields with the magnetocaloric effect includes a high field strength magnet capable of generating a magnetic field of at least 1 Tesla and a magnetocaloric insert disposed within a bore of the high field strength magnet. A method for magnetically processing a specimen includes positioning a specimen adjacent to a magnetocaloric insert within a bore of a magnet and applying a high field strength magnetic field of at least 1 Tesla to the specimen and to the magnetocaloric insert. The temperature of the specimen changes during the application of the high field strength magnetic field due to the magnetocaloric effect.

  13. Skill of ship-following large-eddy simulations in reproducing MAGIC observations across the northeast Pacific stratocumulus to cumulus transition region

    NASA Astrophysics Data System (ADS)

    McGibbon, J.; Bretherton, C. S.

    2017-06-01

    During the Marine ARM GPCI Investigation of Clouds (MAGIC) in October 2011 to September 2012, a container ship making periodic cruises between Los Angeles, CA, and Honolulu, HI, was instrumented with surface meteorological, aerosol and radiation instruments, a cloud radar and ceilometer, and radiosondes. Here large-eddy simulation (LES) is performed in a ship-following frame of reference for 13 four day transects from the MAGIC field campaign. The goal is to assess if LES can skillfully simulate the broad range of observed cloud characteristics and boundary layer structure across the subtropical stratocumulus to cumulus transition region sampled during different seasons and meteorological conditions. Results from Leg 15A, which sampled a particularly well-defined stratocumulus to cumulus transition, demonstrate the approach. The LES reproduces the observed timing of decoupling and transition from stratocumulus to cumulus and matches the observed evolution of boundary layer structure, cloud fraction, liquid water path, and precipitation statistics remarkably well. Considering the simulations of all 13 cruises, the LES skillfully simulates the mean diurnal variation of key measured quantities, including liquid water path (LWP), cloud fraction, measures of decoupling, and cloud radar-derived precipitation. The daily mean quantities are well represented, and daily mean LWP and cloud fraction show the expected correlation with estimated inversion strength. There is a -0.6 K low bias in LES near-surface air temperature that results in a high bias of 5.6 W m-2 in sensible heat flux (SHF). Overall, these results build confidence in the ability of LES to represent the northeast Pacific stratocumulus to trade cumulus transition region.Plain Language SummaryDuring the Marine ARM GPCI Investigation of Clouds (MAGIC) field campaign in October 2011 to September 2012, a cargo container ship making regular cruises between Los Angeles, CA, and Honolulu, HI, was fitted with tools to measure aspects of the clouds and atmosphere above the ship. We used some of these observations to perform high-resolution computer simulations of the atmosphere in the region around the ship, with the goal of testing how well the simulation produces clouds and atmosphere similar to what was observed. Simulations of 13 one-way cruises to Honolulu, HI, were performed. We see the simulations skillfully produce changes in cloud properties that occur at different times of day and have average properties that match well with the observations. One error is that the air near the surface is slightly too cold in the simulations, meaning more heat is transferred up from the surface. Overall, this result builds confidence and trust in the ability of this type of simulation to produce realistic cloud properties in the northeast Pacific.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=paranoid+AND+schizophrenia&pg=2&id=EJ364615','ERIC'); return false;" href="https://eric.ed.gov/?q=paranoid+AND+schizophrenia&pg=2&id=EJ364615"><span>Magical Ideation and Schizophrenia.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>George, Leonard; Neufeld, Richard W. J.</p> <p>1987-01-01</p> <p>Administered the Eckblad and Chapman (1983) Magical Ideation Scale to groups of paranoid and nonparanoid schizophrenics and control subjects. Schizophrenics scored significantly higher than nonschizophrenic patients (mainly cases of affective disorder) and normal control subjects. Discusses theoretical and prognostic utility of this finding.…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=The%2binfluence%2bof%2bsmartphones&pg=3&id=EJ177394','ERIC'); return false;" href="https://eric.ed.gov/?q=The%2binfluence%2bof%2bsmartphones&pg=3&id=EJ177394"><span>Helping, Manipulation, and Magic</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Frey, Louise A.; Edinburg, Golda M.</p> <p>1978-01-01</p> <p>The thesis of this article is that an understanding of the primitive origins of the helping process in myth, magic, and ritual may prevent social workers from engaging in practices that negate their clients' ability to work out their own solutions to problems. (Author)</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ1093254.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ1093254.pdf"><span>Promoting Reasoning through the Magic V Task</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Bragg, Leicha A.; Widjaja, Wanty; Loong, Esther Yook-Kin; Vale, Colleen; Herbert, Sandra</p> <p>2015-01-01</p> <p>Reasoning in mathematics plays a critical role in developing mathematical understandings. In this article, Bragg, Loong, Widjaja, Vale & Herbert explore an adaptation of the Magic V Task and how it was used in several classrooms to promote and develop reasoning skills.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21275192','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21275192"><span>"[N]ot subject to our sense” : Margaret Cavendish's fusion of Renaissance science, magic and fairy lore.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Walters, Lisa</p> <p>2010-01-01</p> <p>This article explores Margaret Cavendish's depictions of alchemy, witchcraft and fairy lore in her scientific treatise Philosophical Letters and in fictional texts from Natures Pictures and Poems and Fancies. Though Cavendish was a dedicated materialist, she appropriates theories of magic from early modern science and folklore into her materialist epistemology. As Cavendish draws upon a fusion of early modern conceptions of magic, she creates a radical theory of matter which not only challenges patriarchy and binary oppositions, but also explores the plurality and mystery that can exist within an infinitely complex material world.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA285052','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA285052"><span>TheE Dynamics of Formation and Evaporation of Mixed Alkali halide Nanocrystals: A Case of Comparable Lattice Energies</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1994-09-21</p> <p>nI131+ mixed nanocrystals containing a " magic " number of 14 metal cations and 13 iodide anions is examined. These nanocrystals were generated through...RbnK14-nl13J+ mixed nanocrystals containing a " magic " number of 14 metal cations and 13 iodide anions is examined. These nanocrystals were generated...deviations or "local maxima" occur at n= 14, 23, 38, and 63 . These n values are called the " magic numbers" and are attributed to the formation of relatively</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1298345-explicit-symplectic-orbit-spin-tracking-method-electric-storage-ring','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1298345-explicit-symplectic-orbit-spin-tracking-method-electric-storage-ring"><span>Explicit symplectic orbit and spin tracking method for electric storage ring</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>Hwang, Kilean; Lee, S. Y.</p> <p>2016-08-18</p> <p>We develop a symplectic charged particle tracking method for phase space coordinates and polarization in all electric storage rings. Near the magic energy, the spin precession tune is proportional to the fractional momentum deviation δ m from the magic energy, and the amplitude of the radial and longitudinal spin precession is proportional to η/δ m, where η is the electric dipole moment for an initially vertically polarized beam. As a result, the method can be used to extract the electron electric dipole moment of a charged particle by employing narrow band frequency analysis of polarization around the magic energy.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011AIPC.1389.1070L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011AIPC.1389.1070L"><span>A Study on the Stream Cipher Embedded Magic Square of Random Access Files</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Liu, Chenglian; Zhao, Jian-Ming; Rafsanjani, Marjan Kuchaki; Shen, Yijuan</p> <p>2011-09-01</p> <p>Magic square and stream cipher issues are both interesting and well-tried topics. In this paper, we are proposing a new scheme which streams cipher applications for random access files based on the magic square method. There are two thresholds required to secure our data, if using only decrypts by the stream cipher. It isn't to recovery original source. On other hand, we improve the model of cipher stream to strengthen and defend efficiently; it also was its own high speed and calculates to most parts of the key stream generator.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_25 --> <div class="footer-extlink text-muted" style="margin-bottom:1rem; text-align:center;">Some links on this page may take you to non-federal websites. 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