Iron Oxide Nanoparticles for Magnetically-Guided and Magnetically-Responsive Drug Delivery

PubMed Central

Estelrich, Joan; Escribano, Elvira; Queralt, Josep; Busquets, Maria Antònia

2015-01-01

In this review, we discuss the recent advances in and problems with the use of magnetically-guided and magnetically-responsive nanoparticles in drug delivery and magnetofection. In magnetically-guided nanoparticles, a constant external magnetic field is used to transport magnetic nanoparticles loaded with drugs to a specific site within the body or to increase the transfection capacity. Magnetofection is the delivery of nucleic acids under the influence of a magnetic field acting on nucleic acid vectors that are associated with magnetic nanoparticles. In magnetically-responsive nanoparticles, magnetic nanoparticles are encapsulated or embedded in a larger colloidal structure that carries a drug. In this last case, an alternating magnetic field can modify the structure of the colloid, thereby providing spatial and temporal control over drug release. PMID:25867479

ON MULTIPLE RECONNECTION X-LINES AND TRIPOLAR PERTURBATIONS OF STRONG GUIDE MAGNETIC FIELDS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eriksson, S.; Gosling, J. T.; Lapenta, G.

We report new multi-spacecraft Cluster observations of tripolar guide magnetic field perturbations at a solar wind reconnection exhaust in the presence of a guide field B{sub M} {sub  }which is almost four times as strong as the reversing field B{sub L}. The novel tripolar field consists of two narrow regions of depressed B{sub M}, with an observed 7%–14% ΔB{sub M} magnitude relative to the external field, which are found adjacent to a wide region of enhanced B{sub M} within the exhaust. A stronger reversing field is associated with each B{sub M} depression. A kinetic reconnection simulation for realistic solar windmore » conditions and the observed strong guide field reveals that tripolar magnetic fields preferentially form across current sheets in the presence of multiple X-lines as magnetic islands approach one another and merge into fewer and larger islands. The simulated ΔB{sub M}/ΔX{sub N} over the normal width ΔX{sub N} between a B{sub M} minimum and the edge of the external region agree with the normalized values observed by Cluster. We propose that a tripolar guide field perturbation may be used to identify candidate regions containing multiple X-lines and interacting magnetic islands at individual solar wind current sheets with a strong guide field.« less

THE MECHANISMS OF ELECTRON ACCELERATION DURING MULTIPLE X LINE MAGNETIC RECONNECTION WITH A GUIDE FIELD

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Huanyu; Lu, Quanming; Huang, Can

2016-04-20

The interactions between magnetic islands are considered to play an important role in electron acceleration during magnetic reconnection. In this paper, two-dimensional particle-in-cell simulations are performed to study electron acceleration during multiple X line reconnection with a guide field. Because the electrons remain almost magnetized, we can analyze the contributions of the parallel electric field, Fermi, and betatron mechanisms to electron acceleration during the evolution of magnetic reconnection through comparison with a guide-center theory. The results show that with the magnetic reconnection proceeding, two magnetic islands are formed in the simulation domain. Next, the electrons are accelerated by both themore » parallel electric field in the vicinity of the X lines and the Fermi mechanism due to the contraction of the two magnetic islands. Then, the two magnetic islands begin to merge into one, and, in such a process, the electrons can be accelerated by both the parallel electric field and betatron mechanisms. During the betatron acceleration, the electrons are locally accelerated in the regions where the magnetic field is piled up by the high-speed flow from the X line. At last, when the coalescence of the two islands into one big island finishes, the electrons can be further accelerated by the Fermi mechanism because of the contraction of the big island. With the increase of the guide field, the contributions of the Fermi and betatron mechanisms to electron acceleration become less and less important. When the guide field is sufficiently large, the contributions of the Fermi and betatron mechanisms are almost negligible.« less

The role of guide field on magnetic reconnection during island coalescence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stanier, Adam John; Daughton, William Scott; Simakov, Andrei Nikolaevich

A number of studies have considered how the rate of magnetic reconnection scales in large and weakly collisional systems by the modelling of long reconnecting current sheets. However, this set-up neglects both the formation of the current sheet and the coupling between the diffusion region and a larger system that supplies the magnetic flux. Recent studies of magnetic island merging, which naturally include these features, have found that ion kinetic physics is crucial to describe the reconnection rate and global evolution of such systems. In this paper, the effect of a guide field on reconnection during island merging is considered.more » In contrast to the earlier current sheet studies, we identify a limited range of guide fields for which the reconnection rate, outflow velocity, and pile-up magnetic field increase in magnitude as the guide field increases. The Hall-MHD fluid model is found to reproduce kinetic reconnection rates only for a sufficiently strong guide field, for which ion inertia breaks the frozen-in condition and the outflow becomes Alfvénic in the kinetic system. The merging of large islands occurs on a longer timescale in the zero guide field limit, which may in part be due to a mirror-like instability that occurs upstream of the reconnection region.« less

The role of guide field on magnetic reconnection during island coalescence

DOE PAGES

Stanier, Adam John; Daughton, William Scott; Simakov, Andrei Nikolaevich; ...

2017-02-01

A number of studies have considered how the rate of magnetic reconnection scales in large and weakly collisional systems by the modelling of long reconnecting current sheets. However, this set-up neglects both the formation of the current sheet and the coupling between the diffusion region and a larger system that supplies the magnetic flux. Recent studies of magnetic island merging, which naturally include these features, have found that ion kinetic physics is crucial to describe the reconnection rate and global evolution of such systems. In this paper, the effect of a guide field on reconnection during island merging is considered.more » In contrast to the earlier current sheet studies, we identify a limited range of guide fields for which the reconnection rate, outflow velocity, and pile-up magnetic field increase in magnitude as the guide field increases. The Hall-MHD fluid model is found to reproduce kinetic reconnection rates only for a sufficiently strong guide field, for which ion inertia breaks the frozen-in condition and the outflow becomes Alfvénic in the kinetic system. The merging of large islands occurs on a longer timescale in the zero guide field limit, which may in part be due to a mirror-like instability that occurs upstream of the reconnection region.« less

Experimental verification of the role of electron pressure in fast magnetic reconnection with a guide field

DOE PAGES

Fox, W.; Sciortino, F.; v. Stechow, A.; ...

2017-03-21

We report detailed laboratory observations of the structure of a reconnection current sheet in a two-fluid plasma regime with a guide magnetic field. We observe and quantitatively analyze the quadrupolar electron pressure variation in the ion-diffusion region, as originally predicted by extended magnetohydrodynamics simulations. The projection of the electron pressure gradient parallel to the magnetic field contributes significantly to balancing the parallel electric field, and the resulting cross-field electron jets in the reconnection layer are diamagnetic in origin. Furthermore, these results demonstrate how parallel and perpendicular force balance are coupled in guide field reconnection and confirm basic theoretical models ofmore » the importance of electron pressure gradients for obtaining fast magnetic reconnection.« less

Magnetic field simulation and shimming analysis of 3.0T superconducting MRI system

NASA Astrophysics Data System (ADS)

Yue, Z. K.; Liu, Z. Z.; Tang, G. S.; Zhang, X. C.; Duan, L. J.; Liu, W. C.

2018-04-01

3.0T superconducting magnetic resonance imaging (MRI) system has become the mainstream of modern clinical MRI system because of its high field intensity and high degree of uniformity and stability. It has broad prospects in scientific research and other fields. We analyze the principle of magnet designing in this paper. We also perform the magnetic field simulation and shimming analysis of the first 3.0T/850 superconducting MRI system in the world using the Ansoft Maxwell simulation software. We guide the production and optimization of the prototype based on the results of simulation analysis. Thus the magnetic field strength, magnetic field uniformity and magnetic field stability of the prototype is guided to achieve the expected target.

Relativistic electron motion in cylindrical waveguide with strong guiding magnetic field and high power microwave

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wu, Ping; Science and Technology on High Power Microwave Laboratory, Northwest Institute of Nuclear Technology, Xi'an 710024; Sun, Jun

2015-06-15

In O-type high power microwave (HPM) devices, the annular relativistic electron beam is constrained by a strong guiding magnetic field and propagates through an interaction region to generate HPM. Some papers believe that the E × B drift of electrons may lead to beam breakup. This paper simplifies the interaction region with a smooth cylindrical waveguide to research the radial motion of electrons under conditions of strong guiding magnetic field and TM{sub 01} mode HPM. The single-particle trajectory shows that the radial electron motion presents the characteristic of radial guiding-center drift carrying cyclotron motion. The radial guiding-center drift is spatiallymore » periodic and is dominated by the polarization drift, not the E × B drift. Furthermore, the self fields of the beam space charge can provide a radial force which may pull electrons outward to some extent but will not affect the radial polarization drift. Despite the radial drift, the strong guiding magnetic field limits the drift amplitude to a small value and prevents beam breakup from happening due to this cause.« less

On the Electron Diffusion Region in Asymmetric Reconnection with a Guide Magnetic Field

NASA Technical Reports Server (NTRS)

Hesse, Michael; Liu, Yi-Hsin; Chen, Li-Jen; Bessho, Naoki; Kuznetsova, Masha; Birn, Joachim; Burch, James L.

2016-01-01

Particle-in-cell simulations in a 2.5-D geometry and analytical theory are employed to study the electron diffusion region in asymmetric reconnection with a guide magnetic field. The analysis presented here demonstrates that similar to the case without guide field, in-plane flow stagnation and null of the in-plane magnetic field are well separated. In addition, it is shown that the electric field at the local magnetic X point is again dominated by inertial effects, whereas it remains dominated by nongyrotropic pressure effects at the in-plane flow stagnation point. A comparison between local electron Larmor radii and the magnetic gradient scale lengths predicts that distribution should become nongyrotropic in a region enveloping both field reversal and flow stagnation points. This prediction is verified by an analysis of modeled electron distributions, which show clear evidence of mixing in the critical region.

Dual aperture dipole magnet with second harmonic component

DOEpatents

Praeg, Walter F.

1985-01-01

An improved dual aperture dipole electromagnet includes a second-harmonic frequency magnetic guide field winding which surrounds first harmonic frequency magnetic guide field windings associated with each aperture. The second harmonic winding and the first harmonic windings cooperate to produce resultant magnetic waveforms in the apertures which have extended acceleration and shortened reset portions of electromagnet operation.

Dual aperture dipole magnet with second harmonic component

DOEpatents

Praeg, W.F.

1983-08-31

An improved dual aperture dipole electromagnet includes a second-harmonic frequency magnetic guide field winding which surrounds first harmonic frequency magnetic guide field windings associated with each aperture. The second harmonic winding and the first harmonic windings cooperate to produce resultant magnetic waveforms in the apertures which have extended acceleration and shortened reset portions of electromagnet operation.

Three-dimensional modeling of electron quasiviscous dissipation in guide-field magnetic reconnection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hesse, Michael; Kuznetsova, Masha; Schindler, Karl

2005-10-01

A numerical study of guide-field magnetic reconnection in a three-dimensional model is presented. Starting from an initial, perturbed, force-free current sheet, it is shown that reconnection develops to an almost translationally invariant state, where magnetic perturbations are aligned primarily along the main current flow direction. An analysis of guide-field and electron flow signatures indicates behavior that is very similar to earlier, albeit not three-dimensional, simulations. Furthermore, a detailed investigation of electron pressure nongyrotropies in the central diffusion region confirms the major role the associated dissipation process plays in establishing the reconnection electric field.

Focusing electrode and coaxial reflector used for reducing the guiding magnetic field of the Ku-band foilless transit-time oscillator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ling, Junpu; Zhang, Jiande; He, Juntao, E-mail: hejuntao12@163.com

2014-08-15

Based on the theoretical analysis of the intense relativistic electron beam propagation in the coaxial drift-tube, a focusing electrode and a coaxial reflector is proposed to lessen the demand of the coaxial Ku-band foilless transit-time oscillator (TTO) for the guiding magnetic field. Moreover, a Ku-band TTO with the focusing electrode and the coaxial reflector is designed and studied by particle in cell simulation. When the diode voltage is 390 kV, the beam current 7.8 kA, and the guiding magnetic field is only 0.3 T, the device can output 820 MW microwave pulse at 14.25 GHz by means of the simulation.more » However, for the device without them, the output power is only 320 MW. The primary experiments are also carried out. When the guiding magnetic field is 0.3 T, the output power of the device with the focusing electrode and the coaxial reflector is double that of the one without them. The simulation and experimental results prove that the focusing electrode and the coaxial reflector are effective on reducing the guiding magnetic field of the device.« less

Simulation investigation of a Ku-band radial line oscillator operating at low guiding magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dang, Fangchao, E-mail: dangfangchao@sina.com; Zhang, Xiaoping; Zhong, Huihuang

2014-06-15

A novel radial line oscillator operating at Ku-band with low guiding magnetic field is proposed in this paper. By using an oversized radial structure, the power handling capacity is enhanced significantly. Based on the small-signal theory, the π/2 mode in radial TM{sub 01} mode is selected as the working mode. Furthermore, a radial uniform guiding magnetic field, made up of four solenoids, is designed. As indicated in 2.5-dimensional fully electromagnetic particle-in-cell simulation, high power microwaves with a power of 2.2 GW and a frequency of 14.25 GHz are generated with over 40% efficiency when the electron beam voltage is 300 kV, themore » beam current 18 kA, and the guiding magnetic field is only 0.6 T. There is no angular non-asymmetric mode discovered in three-dimensional simulation.« less

The role of kinetic ion physics in the interaction of magnetic islands

NASA Astrophysics Data System (ADS)

Stanier, A.

2016-12-01

Magnetic islands are two-dimensional representations of magnetic flux-ropes, a fundamental building block of magnetized plasmas. Here we model magnetic reconnection during the coalescence of magnetic islands with a range of guide fields that have application to the Earth's magnetosphere. It is demonstrated that the Hall-MHD model is able to reproduce the reconnection rates of the fully kinetic system only in the presence of a fairly strong guide field (Bg≥ 3Bx). In the weak guide field limit non-isotropic ion pressure tensor effects that are missing from Hall-MHD are crucial to describe many key features of this reconnection test-problem [1], including the peak and average rates, pile-up field, outflow velocity, and global evolution of the system. A hybrid model which retains the full kinetic physics for ions along with mass-less fluid electrons gives good agreement with fully kinetic results for the full range of guide fields considered. These results suggest that kinetic ions may be important for a large number of reconnection events in the Earth's magnetosphere. References: [1] A. Stanier, W. Daughton, L. Chacon, H. Karimabadi, J. Ng, Y.-M. Huang, A. Hakim, and A. Bhattacharjee, Phys. Rev. Lett. 115, 175004 (2015).

Energy Dissipation and Dynamics in Large Guide Field Turbulence Driven Reconnection at the Magnetopause

NASA Astrophysics Data System (ADS)

TenBarge, J. M.; Shay, M. A.; Sharma, P.; Juno, J.; Haggerty, C. C.; Drake, J. F.; Bhattacharjee, A.; Hakim, A.

2017-12-01

Turbulence and magnetic reconnection are the primary mechanisms responsible for the conversion of stored magnetic energy into particle energy in many space and astrophysical plasmas. The magnetospheric multiscale mission (MMS) has given us unprecedented access to high cadence particle and field data of turbulence and magnetic reconnection at earth's magnetopause. The observations include large guide field reconnection events generated within the turbulent magnetopause. Motivated by these observations, we present a study of large guide reconnection using the fully kinetic Eulerian Vlasov-Maxwell component of the Gkeyll simulation framework, and we also employ and compare with gyrokinetics to explore the asymptotically large guide field limit. In addition to studying the configuration space dynamics, we leverage the recently developed field-particle correlations to diagnose the dominant sources of dissipation and compare the results of the field-particle correlation to other energy dissipation measures.

3D MHD Simulations of Laser Plasma Guiding in Curved Magnetic Field

NASA Astrophysics Data System (ADS)

Roupassov, S.; Rankin, R.; Tsui, Y.; Capjack, C.; Fedosejevs, R.

1999-11-01

The guiding and confinement of laser produced plasma in a curved magnetic field has been investigated numerically. These studies were motivated by experiments on pulsed laser deposition of diamond-like films [1] in which a 1kG magnetic field in a curved solenoid geometry was utilized to steer a carbon plasma around a curved trajectory and thus to separate it from unwanted macroparticles produced by the laser ablation. The purpose of the modeling was to characterize the plasma dynamics during the propagation through the magnetic guide field and to investigate the effect of different magnetic field configurations. A 3D curvilinear ADI code developed on the basis of an existing Cartesian code [2] was employed to simulate the underlying resistive one-fluid MHD model. Issues such as large regions of low background density and nonreflective boundary conditions were addressed. Results of the simulations in a curved guide field will be presented and compared to experimental results. [1] Y.Y. Tsui, D. Vick and R. Fedosejevs, Appl. Phys. Lett. 70 (15), pp. 1953-57, 1997. [2] R. Rankin, and I. Voronkov, in "High Performance Computing Systems and Applications", pp. 59-69, Kluwer AP, 1998.

On Multiple Hall-Like Electron Currents and Tripolar Guide Magnetic Field Perturbations During Kelvin-Helmholtz Waves

NASA Astrophysics Data System (ADS)

Sturner, Andrew P.; Eriksson, Stefan; Nakamura, Takuma; Gershman, Daniel J.; Plaschke, Ferdinand; Ergun, Robert E.; Wilder, Frederick D.; Giles, Barbara; Pollock, Craig; Paterson, William R.; Strangeway, Robert J.; Baumjohann, Wolfgang; Burch, James L.

2018-02-01

Two magnetopause current sheet crossings with tripolar guide magnetic field signatures were observed by multiple Magnetosphere Multiscale (MMS) spacecraft during Kelvin-Helmholtz wave activity. The two out-of-plane magnetic field depressions of the tripolar guide magnetic field are largely supported by the observed in-plane electron currents, which are reminiscent of two clockwise Hall current loop systems. A comparison with a three-dimensional kinetic simulation of Kelvin-Helmholtz waves and vortex-induced reconnection suggests that MMS likely encountered the two Hall magnetic field depressions on either side of a magnetic reconnection X-line. Moreover, MMS observed an out-of-plane current reversal and a corresponding in-plane magnetic field rotation at the center of one of the current sheets, suggesting the presence of two adjacent flux ropes. The region inside one of the ion-scale flux ropes was characterized by an observed decrease of the total magnetic field, a strong axial current, and significant enhancements of electron density and parallel electron temperature. The flux rope boundary was characterized by currents opposite this axial current, strong in-plane and converging electric fields, parallel electric fields, and weak electron-frame Joule dissipation. These return current region observations may reflect a need to support the axial current rather than representing local reconnection signatures in the absence of any exhausts.

Toroidal regularization of the guiding center Lagrangian

DOE PAGES

Burby, J. W.; Ellison, C. L.

2017-11-22

In the Lagrangian theory of guiding center motion, an effective magnetic field B* = B+ (m/e)v ∥∇ x b appears prominently in the equations of motion. Because the parallel component of this field can vanish, there is a range of parallel velocities where the Lagrangian guiding center equations of motion are either ill-defined or very badly behaved. Moreover, the velocity dependence of B* greatly complicates the identification of canonical variables and therefore the formulation of symplectic integrators for guiding center dynamics. Here, this letter introduces a simple coordinate transformation that alleviates both these problems simultaneously. In the new coordinates, themore » Liouville volume element is equal to the toroidal contravariant component of the magnetic field. Consequently, the large-velocity singularity is completely eliminated. Moreover, passing from the new coordinate system to canonical coordinates is extremely simple, even if the magnetic field is devoid of flux surfaces. We demonstrate the utility of this approach in regularizing the guiding center Lagrangian by presenting a new and stable one-step variational integrator for guiding centers moving in arbitrary time-dependent electromagnetic fields.« less

Toroidal regularization of the guiding center Lagrangian

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burby, J. W.; Ellison, C. L.

In the Lagrangian theory of guiding center motion, an effective magnetic field B* = B+ (m/e)v ∥∇ x b appears prominently in the equations of motion. Because the parallel component of this field can vanish, there is a range of parallel velocities where the Lagrangian guiding center equations of motion are either ill-defined or very badly behaved. Moreover, the velocity dependence of B* greatly complicates the identification of canonical variables and therefore the formulation of symplectic integrators for guiding center dynamics. Here, this letter introduces a simple coordinate transformation that alleviates both these problems simultaneously. In the new coordinates, themore » Liouville volume element is equal to the toroidal contravariant component of the magnetic field. Consequently, the large-velocity singularity is completely eliminated. Moreover, passing from the new coordinate system to canonical coordinates is extremely simple, even if the magnetic field is devoid of flux surfaces. We demonstrate the utility of this approach in regularizing the guiding center Lagrangian by presenting a new and stable one-step variational integrator for guiding centers moving in arbitrary time-dependent electromagnetic fields.« less

The effect of guide-field and boundary conditions on collisionless magnetic reconnection in a stressed X-point collapse

DOE Office of Scientific and Technical Information (OSTI.GOV)

Graf von der Pahlen, J.; Tsiklauri, D.

2014-01-15

Works of Tsiklauri and Haruki [Phys. Plasmas 15, 102902 (2008); 14, 112905 (2007)] are extended by inclusion of the out-of-plane magnetic (guide) field. In particular, magnetic reconnection during collisionless, stressed X-point collapse for varying out-of-plane guide-fields is studied using a kinetic, 2.5D, fully electromagnetic, relativistic particle-in-cell numerical code. For zero guide-field, cases for both open and closed boundary conditions are investigated, where magnetic flux and particles are lost and conserved, respectively. It is found that reconnection rates, out-of-plane currents and density in the X-point increase more rapidly and peak sooner in the closed boundary case, but higher values are reachedmore » in the open boundary case. The normalized reconnection rate is fast: 0.10-0.25. In the open boundary case it is shown that an increase of guide-field yields later onsets in the reconnection peak rates, while in the closed boundary case initial peak rates occur sooner but are suppressed. The reconnection current changes similarly with increasing guide-field; however for low guide-fields the reconnection current increases, giving an optimal value for the guide-field between 0.1 and 0.2 times the in-plane field in both cases. Also, in the open boundary case, it is found that for guide-fields of the order of the in-plane magnetic field, the generation of electron vortices occurs. Possible causes of the vortex generation, based on the flow of decoupled particles in the diffusion region and localized plasma heating, are discussed. Before peak reconnection onset, oscillations in the out-of-plane electric field at the X-point are found, ranging in frequency from approximately 1 to 2 ω{sub pe} and coinciding with oscillatory reconnection. These oscillations are found to be part of a larger wave pattern in the simulation domain. Mapping the out-of-plane electric field along the central lines of the domain over time and applying a 2D Fourier transform reveal that the waves predominantly correspond to the ordinary and the extraordinary mode and hence may correspond to observable radio waves such as solar radio burst fine structure spikes.« less

Integrated simulation of magnetic-field-assist fast ignition laser fusion

NASA Astrophysics Data System (ADS)

Johzaki, T.; Nagatomo, H.; Sunahara, A.; Sentoku, Y.; Sakagami, H.; Hata, M.; Taguchi, T.; Mima, K.; Kai, Y.; Ajimi, D.; Isoda, T.; Endo, T.; Yogo, A.; Arikawa, Y.; Fujioka, S.; Shiraga, H.; Azechi, H.

2017-01-01

To enhance the core heating efficiency in fast ignition laser fusion, the concept of relativistic electron beam guiding by external magnetic fields was evaluated by integrated simulations for FIREX class targets. For the cone-attached shell target case, the core heating performance deteriorates by applying magnetic fields since the core is considerably deformed and most of the fast electrons are reflected due to the magnetic mirror formed through the implosion. On the other hand, in the case of a cone-attached solid ball target, the implosion is more stable under the kilo-tesla-class magnetic field. In addition, feasible magnetic field configuration is formed through the implosion. As a result, the core heating efficiency doubles by magnetic guiding. The dependence of core heating properties on the heating pulse shot timing was also investigated for the solid ball target.

The Role of Compressibility in Energy Release by Magnetic Reconnection

NASA Technical Reports Server (NTRS)

Birn, J.; Borovosky, J. E.; Hesse, M.

2012-01-01

Using resistive compressible magnetohydrodynamics, we investigate the energy release and transfer by magnetic reconnection in finite (closed or periodic) systems. The emphasis is on the magnitude of energy released and transferred to plasma heating in configurations that range from highly compressible to incompressible, based on the magnitude of the background beta (ratio of plasma pressure over magnetic pressure) and of a guide field in two-dimensional reconnection. As expected, the system becomes more incompressible, and the role of compressional heating diminishes, with increasing beta or increasing guide field. Nevertheless, compressional heating may dominate over Joule heating for values of the guide field of 2 or 3 (in relation to the reconnecting magnetic field component) and beta of 5-10. This result stems from the strong localization of the dissipation near the reconnection site, which is modeled based on particle simulation results. Imposing uniform resistivity, corresponding to a Lundquist number of 10(exp 3) to 10(exp 4), leads to significantly larger Ohmic heating. Increasing incompressibility greatly reduces the magnetic flux transfer and the amount of energy released, from approx. 10% of the energy associated with the reconnecting field component, for zero guide field and low beta, to approx. 0.2%-0.4% for large values of the guide field B(sub y0) > 5 or large beta. The results demonstrate the importance of taking into account plasma compressibility and localization of dissipation in investigations of heating by turbulent reconnection, possibly relevant for solar wind or coronal heating.

Energy release and transfer in guide field reconnection

NASA Astrophysics Data System (ADS)

Birn, J.; Hesse, M.

2010-01-01

Properties of energy release and transfer by magnetic reconnection in the presence of a guide field are investigated on the basis of 2.5-dimensional magnetohydrodynamic (MHD) and particle-in-cell (PIC) simulations. Two initial configurations are considered: a plane current sheet with a uniform guide field of 80% of the reconnecting magnetic field component and a force-free current sheet in which the magnetic field strength is constant but the field direction rotates by 180° through the current sheet. The onset of reconnection is stimulated by localized, temporally limited compression. Both MHD and PIC simulations consistently show that the outgoing energy fluxes are dominated by (redirected) Poynting flux and enthalpy flux, whereas bulk kinetic energy flux and heat flux (in the PIC simulation) are small. The Poynting flux is mainly associated with the magnetic energy of the guide field which is carried from inflow to outflow without much alteration. The conversion of annihilated magnetic energy to enthalpy flux (that is, thermal energy) stems mainly from the fact that the outflow occurs into a closed field region governed by approximate force balance between Lorentz and pressure gradient forces. Therefore, the energy converted from magnetic to kinetic energy by Lorentz force acceleration becomes immediately transferred to thermal energy by the work done by the pressure gradient force. Strong similarities between late stages of MHD and PIC simulations result from the fact that conservation of mass and entropy content and footpoint displacement of magnetic flux tubes, imposed in MHD, are also approximately satisfied in the PIC simulations.

Design of pulsed guiding magnetic field for high power microwave generators.

PubMed

Ju, J-C; Zhang, H; Zhang, J; Shu, T; Zhong, H-H

2014-09-01

In this paper, we present a comprehensive study on designing solenoid together with the corresponding power supply system to excite pulsed magnetic field required for high power microwave generators. Particularly, a solenoid is designed and the excited magnetic field is applied to a Ku-band overmoded Cerenkov generator. It is found in experiment that the electron beam is properly guided by the magnetic field and a 1.1 GW high power microwave is achieved at a central frequency of 13.76 GHz. Pulsed solenoid system has the advantages of compactness and low energy consumption, which are of great interest for repetitive operation. The reported studies and results can be generalized to other applications which require magnetic fields.

Electric field with bipolar structure during magnetic reconnection without a guide field

NASA Astrophysics Data System (ADS)

Guo, Jun

2014-05-01

We present a study on the polarized electric field during the collisionless magnetic reconnection of antiparallel fields using two dimensional particle-in-cell simulations. The simulations demonstrate clearly that electron holes and electric field with bipolar structure are produced during magnetic reconnection without a guide field. The electric field with bipolar structure can be found near the X-line and on the separatrix and the plasma sheet boundary layer, which is consistent with the observations. These structures will elongate electron's time staying in the diffusion region. In addition, the electric fields with tripolar structures are also found in our simulation.

TU-H-BRA-02: The Physics of Magnetic Field Isolation in a Novel Compact Linear Accelerator Based MRI-Guided Radiation Therapy System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Low, D; Mutic, S; Shvartsman, S

Purpose: To develop a method for isolating the MRI magnetic field from field-sensitive linear accelerator components at distances close to isocenter. Methods: A MRI-guided radiation therapy system has been designed that integrates a linear accelerator with simultaneous MR imaging. In order to accomplish this, the magnetron, port circulator, radiofrequency waveguide, gun driver, and linear accelerator needed to be placed in locations with low magnetic fields. The system was also required to be compact, so moving these components far from the main magnetic field and isocenter was not an option. The magnetic field sensitive components (exclusive of the waveguide) were placedmore » in coaxial steel sleeves that were electrically and mechanically isolated and whose thickness and placement were optimized using E&M modeling software. Six sets of sleeves were placed 60° apart, 85 cm from isocenter. The Faraday effect occurs when the direction of propagation is parallel to the magnetic RF field component, rotating the RF polarization, subsequently diminishing RF power. The Faraday effect was avoided by orienting the waveguides such that the magnetic field RF component was parallel to the magnetic field. Results: The magnetic field within the shields was measured to be less than 40 Gauss, significantly below the amount needed for the magnetron and port circulator. Additional mu-metal was employed to reduce the magnetic field at the linear accelerator to less than 1 Gauss. The orientation of the RF waveguides allowed the RT transport with minimal loss and reflection. Conclusion: One of the major challenges in designing a compact linear accelerator based MRI-guided radiation therapy system, that of creating low magnetic field environments for the magnetic-field sensitive components, has been solved. The measured magnetic fields are sufficiently small to enable system integration. This work supported by ViewRay, Inc.« less

Manipulation of permanent magnetic polymer micro-robots: a new approach towards guided wireless capsule endoscopy

NASA Astrophysics Data System (ADS)

Hilbich, D.; Rahbar, A.; Khosla, A.; Gray, B. L.

2012-10-01

We present the initial experimental results for manipulating micro-robots featuring permanent magnetic polymer magnets for guided wireless endoscopy applications. The magnetic polymers are fabricated by doping polydimethylsiloxane (PDMS) with permanent isotropic rare earth magnetic powder (MQFP 12-5) with an average particle size of 6 μm. The prepared magnetic nanocomposite polymer (M-NCP) is patterned in the desired shape against a plexiglass mold via soft lithography techniques. It is observed that the fabricated micro-robot magnets have a magnetic field strength of 50 mT and can easily be actuated by applying a field of 8.3 mT (field measured at the capsule's position) and moved at a rate of 5 inches/second.

The Effect of a Guide Field on Local Energy Conversion During Asymmetric Magnetic Reconnection: Particle-in-Cell Simulations

NASA Astrophysics Data System (ADS)

Cassak, P. A.; Genestreti, K. J.; Burch, J. L.; Phan, T.-D.; Shay, M. A.; Swisdak, M.; Drake, J. F.; Price, L.; Eriksson, S.; Ergun, R. E.; Anderson, B. J.; Merkin, V. G.; Komar, C. M.

2017-11-01

We use theory and simulations to study how the out-of-plane (guide) magnetic field strength modifies the location where the energy conversion rate between the electric field and the plasma is appreciable during asymmetric magnetic reconnection, motivated by observations (Genestreti et al., 2017). For weak guide fields, energy conversion is maximum on the magnetospheric side of the X line, midway between the X line and electron stagnation point. As the guide field increases, the electron stagnation point gets closer to the X line, and energy conversion occurs closer to the electron stagnation point. We motivate one possible nonrigorous approach to extend the theory of the stagnation point location to include a guide field. The predictions are compared to two-dimensional particle-in-cell (PIC) simulations with vastly different guide fields. The simulations have upstream parameters corresponding to three events observed with Magnetospheric Multiscale (MMS). The predictions agree reasonably well with the simulation results, capturing trends with the guide field. The theory correctly predicts that the X line and stagnation points approach each other as the guide field increases. The results are compared to MMS observations, Active Magnetosphere and Planetary Electrodynamics Response Experiment (AMPERE) observations of each event, and a global resistive-magnetohydrodynamics simulation of the 16 October 2015 event. The PIC simulation results agree well with the global observations and simulation but differ in the strong electric fields and energy conversion rates found in MMS observations. The observational, theoretical, and numerical results suggest that the strong electric fields observed by MMS do not represent a steady global reconnection rate.

The effect of a guide field on local energy conversion during asymmetric magnetic reconnection: Particle-in-cell simulations

NASA Astrophysics Data System (ADS)

Cassak, P.; Genestreti, K.; Burch, J. L.; Shay, M.; Swisdak, M.; Drake, J. F.; Price, L.; Eriksson, S.; Anderson, B. J.; Merkin, V. G.; Komar, C. M.; Phan, T.; Ergun, R.

2017-12-01

We use theoretical and computational techniques to study how the out-of-plane (guide) magnetic field strength modifies the location where the energy conversion rate between the electric field and the plasma is appreciable during asymmetric magnetic reconnection, motivated by observations by Genestreti et al. (J. Geophys. Res, submitted). For weak guide fields, the energy conversion rate is maximum midway between the X-line and electron stagnation point. As the guide field increases, it moves towards the electron stagnation point. We motivate how to extend the theory of the location of the stagnation points to include the effect of a guide field. The predictions are compared to two-dimensional (2D) particle-in-cell (PIC) simulations with vastly different guide fields. The simulations have upstream parameters corresponding to three reconnection events observed with MMS. The predictions agree reasonably well with the simulation results, having captured trends with the guide field. The theory correctly predicts that the energy conversion is closer to the X-line in the absolute sense as the guide field increases. The results are then compared to MMS observations, Active Magnetosphere and Planetary Electrodynamics Response Experiment (AMPERE) observations of each event, and global resistive magnetohydrodynamics simulations of the 2015 Oct 16 event. The PIC simulation results agree well with the global observations and simulations, but differ in the strong electric fields and energy conversion rates found in the MMS observations. The results suggest that the strong electric fields observed by MMS do not represent a steady global rate.

Electron heating and acceleration during magnetic reconnection

NASA Astrophysics Data System (ADS)

Dahlin, Joel

2017-10-01

Magnetic reconnection is thought to be an important driver of energetic particles in a variety of astrophysical phenomena such as solar flares and magnetospheric storms. However, the observed fraction of energy imparted to a nonthermal component can vary widely in different regimes. We use kinetic particle-in-cell (PIC) simulations to demonstrate the important role of the non-reversing (guide) field in controlling the efficiency of electron acceleration in collisionless reconnection. In reconnection where the guide field is smaller than the reconnecting component, the dominant electron accelerator is a Fermi-type mechanism that preferentially energizes the most energetic particles. In strong guide field reconnection, the field-line contraction that drives the Fermi mechanism becomes weak. Instead, parallel electric fields are primarily responsible for driving electron heating but are ineffective in driving the energetic component of the spectrum. Three-dimensional simulations reveal that the stochastic magnetic field that develops during 3D guide field reconnection plays a vital role in particle acceleration and transport. The reconnection outflows that drive Fermi acceleration also expel accelerating particles from energization regions. In 2D reconnection, electrons are trapped in island cores and acceleration ceases, whereas in 3D the stochastic magnetic field enables energetic electrons to leak out of islands and freely sample regions of energy release. A finite guide field is required to break initial 2D symmetry and facilitate escape from island structures. We show that reconnection with a guide field comparable to the reconnecting field generates the greatest number of energetic electrons, a regime where both (a) the Fermi mechanism is an efficient driver and (b) energetic electrons may freely access acceleration sites. These results have important implications for electron acceleration in solar flares and reconnection-driven dissipation in turbulence.

Laboratory Experiment of Magnetic Reconnection between Merging Flux Tubes with Strong Guide FIeld

NASA Astrophysics Data System (ADS)

Inomoto, M.; Kamio, S.; Kuwahata, A.; Ono, Y.

2013-12-01

Magnetic reconnection governs variety of energy release events in the universe, such as solar flares, geomagnetic substorms, and sawtooth crash in laboratory nuclear fusion experiments. Differently from the classical steady reconnection models, non-steady behavior of magnetic reconnection is often observed. In solar flares, intermittent enhancement of HXR emission is observed synchronously with multiple ejection of plammoids [1]. In laboratory reconnection experiments, the existence of the guide field, that is perpendicular to the reconnection field, makes significant changes on reconnection process. Generally the guide field will slow down the reconnection rate due to the increased magnetic pressure inside the current sheet. It also brings about asymmetric structure of the separatrices or effective particle acceleration in collisionless conditions. We have conducted laboratory experiments to study the behavior of the guide-field magnetic reconnection using plasma merging technique (push reconnection). Under substantial guide field even larger than the reconnection field, the reconnection generally exhibits non-steady feature which involves intermittent detachment of X-point and reconnection current center[2]. Transient enhancement of reconnection rate is observed simultaneously with the X-point motion[3]. We found two distinct phenomena associated with the guide-field non-steady reconnection. The one is the temporal and localized He II emission from X-point region, suggesting the production of energetic electrons which could excite the He ions in the vicinity of the X-point. The other is the excitation of large-amplitude electromagnetic waves which have similar properties with kinetic Alfven waves, whose amplitude show positive correlation with the enhancement of the reconnection electric field[4]. Electron beam instability caused by the energetic electrons accelerated to more than twice of the electron thermal velocity could be a potential driver of the monochromatic magnetic fluctuations. In conclusion, the laboratory guide field reconnection experiments showed some unique features such as ejection of current sheet, localized enhancement of emission, and excitation of low frequency waves, suggesting intermittent fast reconnection mechanism with significant electron acceleration. [1] N. Nishizuka et al., Astrophysical J. 711, 1062 (2010). [2] Y. Ono et al., Phys. Plasmas 18, 111213 (2011). [3] M. Inomoto et al., Plasma and Fusion Res. 8, 2401112 (2013). [4] M. Inomoto et al., Phys. Plasmas 20, 061209 (2013).

Magnetospheric Multiscale Observations of the Electron Diffusion Region of Large Guide Field Magnetic Reconnection

NASA Technical Reports Server (NTRS)

Eriksson, S.; Wilder, F. D.; Ergun, R. E.; Schwartz, S. J.; Cassak, P. A.; Burch, J. L.; Chen, Li-Jen; Torbert, R. B.; Phan, T. D.; Lavraud, B.;

A Study of Reconnection Poleward of Cusp: Cluster and Polar

NASA Astrophysics Data System (ADS)

Muzamil, Fathima

Asymmetries in plasma density and the presence of a guide field significantly alter the structure of the ion diffusion region (IDR) in symmetric, collisionless reconnection. These features have been shown by numerical simulations under moderate density asymmetries ( 10), and theoretical analyses. However, very few studies have addressed these issues with in-situ observations, particularly at high magnetic latitudes. By the structure of the IDR we refer to features such as the non-colocation of the X-line and stagnation line, the distortion of the Hall magnetic and electric fields, outflow speed, outflow density etc. We have compiled a collection of Cluster crossings of the high-latitude magnetopause poleward of the cusp under northward interplanetary magnetic field in the years 2001-2008. We identified 18 events that fulfilled the criteria that was used as plausible evidence for an IDR crossing. A wide range of guide fields (6 to 74%) and very high density asymmetries (over three orders of magnitude) were present in this event list. The total DC electric field ranged from 10 mV/m-72 mV/m. We compared theoretical predictions for ion outflow speed and density against measured values for events with least magnetic shear and found good agreement. Peak values of both measured quantities agreed better than the average values. The separation between the X and S-lines were measured for two events. The separation was in the order of 2 ion inertial lengths. We presented a detailed analysis of a current sheet crossing hallmarked by a density asymmetry of 2 orders of magnitude ( 140) [Muzamil et al., 2014, JGR]. This event was measured by the Polar spacecraft, also at high latitudes poleward of the cusp. Data agreed well with simulation results, especially the observation of density cavities together with isolated electric fields in the normal direction at both separatrices. This has not been observed in previous observational studies. Effect of the guide field on both sides of the X-line was examined using two events with jet reversals and similar guide fields. A sunward-tailward asymmetry in the Hall magnetic field structure was observed due to the guide field in the two outflow regions. The Hall field was weakened and changed polarity in the vicinity of the X-line due to an electron velocity shear layer. Using three other crossings with high guide fields, we measured a 40-60% enhancement in the Hall magnetic field showing consistency with simulations. We then presented a case study of large episodic magnetic field depressions in the magnetosheath boundary layer region near the magnetic separatrix. We identified specific characteristics and compared them to possible generating mechanisms. The most plausible one was kinetic Alfven waves. Thus, we have provided observational evidence for the structure of the IDR in poleward of the cusp under several different asymmetric conditions and guide fields.

E-beam ionized channel guiding of an intense relativistic electron beam

DOEpatents

Frost, Charles A.; Godfrey, Brendon B.; Kiekel, Paul D.; Shope, Steven L.

1988-01-01

An IREB is guided through a curved path by ionizing a channel in a gas with electrons from a filament, and confining the electrons to the center of the path with a magnetic field extending along the path. The magnetic field is preferably generated by a solenoid extending along the path.

Particle-in-cell simulations of asymmetric guide-field reconnection: quadrupolar structure of Hall magnetic field

NASA Astrophysics Data System (ADS)

Schmitz, R. G.; Alves, M. V.; Barbosa, M. V. G.

2017-12-01

One of the most important processes that occurs in Earth's magnetosphere is known as magnetic reconnection (MR). This process can be symmetric or asymmetric, depending basically on the plasma density and magnetic field in both sides of the current sheet. A good example of symmetric reconnection in terrestrial magnetosphere occurs in the magnetotail, where these quantities are similar on the north and south lobes. In the dayside magnetopause MR is asymmetric, since the plasma regimes and magnetic fields of magnetosheath and magnetosphere are quite different. Symmetric reconnection has some unique signatures. For example, the formation of a quadrupolar structure of Hall magnetic field and a bipolar Hall electric field that points to the center of the current sheet. The different particle motions in the presence of asymmetries change these signatures, causing the quadrupolar pattern to be distorted and forming a bipolar structure. Also, the bipolar Hall electric field is modified and gives rise to a single peak pointing toward the magnetosheat, considering an example of magnetopause reconnection. The presence of a guide-field can also distort the quadrupolar pattern, by giving a shear angle across the current sheet and altering the symmetric patterns, according to previous simulations and observations. Recently, a quadrupolar structure was observed in an asymmetric guide-field MR event using MMS (Magnetospheric Multiscale) mission data [Peng et al., JGR, 2017]. This event shows clearly that the density asymmetry and the guide-field were not sufficient to form signatures of asymmetric reconnection. Using the particle-in-cell code iPIC3D [Markidis et al, Mathematics and Computers in Simulation, 2010] with the MMS data from this event used to define input parameters, we found a quadrupolar structure of Hall magnetic field and a bipolar pattern of Hall electric field in ion scales, showing that our results are in an excellent agreement with the MMS observations. To our knowledge, this is the first time PIC simulations show this kind of results, since previous simulations have predicted bipolar pattern in the asymmetric guide-field reconnection.

Preliminary research on overmoded high-power millimeter-wave Cerenkov generator with dual-cavity reflector in low guiding magnetic field

NASA Astrophysics Data System (ADS)

Ye, Hu; Chen, Changhua; Ning, Hui; Tan, Weibing; Teng, Yan; Shi, Yanchao; Wu, Ping; Song, Zhimin; Cao, Yibing; Du, Zhaoyu

2015-12-01

This paper presents preliminary research on a V-band overmoded Cerenkov generator with dual-cavity reflector operating in a low guiding magnetic field. It is found that the fluctuation of the electron envelope in the low guiding magnetic field can be predicted using an equivalent coaxial model of a foilless diode, and a dual-cavity reflector based on the model matching method can provide strong reflection at the front end of the overmoded structures so that any microwave power that leaks into the diode region can be effectively suppressed. Numerical simulations indicate that the control of the beam envelope and the use of the dual-cavity reflector ease generator operation in the low guiding magnetic field. In the experimental research, the fluctuation of the annular electron beam with the outer radius of 7.5 mm measures approximately 0.7 mm, which is in good agreement with the theoretical results. The disturbance caused by power leaking from the overmoded slow wave structure is eliminated by the dual-cavity reflector. With accurate fabrication and assembly processes, an operating frequency of 61.6 GHz is attained by the fifth harmonic heterodyne method, and the output power is measured to be approximately 123 MW by the far-field measurement method at a diode voltage of 445 kV, a beam current of 4.45 kA, and under a guiding magnetic field of 1.45 T. The output mode is measured using an array of neon flash bulbs, and the pulse shortening phenomenon is both observed and analyzed.

Principles and Design of a Zeeman–Sisyphus Decelerator for Molecular Beams

PubMed Central

Tarbutt, M. R.

2016-01-01

Abstract We explore a technique for decelerating molecules using a static magnetic field and optical pumping. Molecules travel through a spatially varying magnetic field and are repeatedly pumped into a weak‐field seeking state as they move towards each strong field region, and into a strong‐field seeking state as they move towards weak field. The method is time‐independent and so is suitable for decelerating both pulsed and continuous molecular beams. By using guiding magnets at each weak field region, the beam can be simultaneously guided and decelerated. By tapering the magnetic field strength in the strong field regions, and exploiting the Doppler shift, the velocity distribution can be compressed during deceleration. We develop the principles of this deceleration technique, provide a realistic design, use numerical simulations to evaluate its performance for a beam of CaF, and compare this performance to other deceleration methods. PMID:27629547

The effect of guide-field and boundary conditions on the features and signatures of collisionless magnetic reconnection in a stressed X-point collapse

NASA Astrophysics Data System (ADS)

Graf von der Pahlen, J.; Tsiklauri, D.

2015-12-01

Magnetic X-point collapse is investigated using a 2.5D fully relativistic particle-in-cell simulation, with varying strengths of guide-field as well as open and closed boundary conditions. In the zero guide-field case we discover a new signature of Hall-reconnection in the out-of-plane magnetic field, namely an octupolar pattern, as opposed to the well-studied quadrupolar out-of-plane field of reconnection. The emergence of the octupolar components was found to be caused by ion currents and is a general feature of X-point collapse. In a comparative study of tearing-mode reconnection, signatures of octupolar components are found only in the out-flow region. It is argued that space-craft observations of magnetic fields at reconnection sites may be used accordingly to identify the type of reconnection [1][2]. Further, initial oscillatory reconnection is observed, prior to reconnection onset, generating electro-magnetic waves at the upper-hybrid frequency, matching solar flare progenitor emission. When applying a guide-field, in both open and closed boundary conditions, thinner dissipation regions are obtained and the onset of reconnection is increasingly delayed. Investigations with open boundary conditions show that, for guide-fields close to the strength of the in-plane field, shear flows emerge, leading to the formation of electron flow vortices and magnetic islands [3]. Asymmetries in the components of the generalised Ohm's law across the dissipation region are observed. Extended in 3D geometry, it is shown that locations of magnetic islands and vortices are not constant along the height of the current-sheet. Vortices formed on opposite sites of the current-sheet travel in opposite directions along it, leading to a criss-cross vortex pattern. Possible instabilities resulting from this specific structure formation are to be investigated [4].[1] J. Graf von der Pahlen and D. Tsiklauri, Phys. Plasmas 21, 060705 (2014), [2] J. Graf von der Pahlen and D. Tsiklauri, Phys. Plasmas 22, 032905 (2015) [3] J. Graf von der Pahlen and D. Tsiklauri, Phys. Plasmas 21, 012901 (2014), [4] http://astro.qmul.ac.uk/~tsiklauri/jgvdpdt4.pdf

Diffusion region in magnetopause reconnection observed by the MMS mission

NASA Astrophysics Data System (ADS)

Chen, Li-Jen

2017-10-01

The diffusion region is the primary location where the plasmas are energized to dissipate the magnetic energy in reconnection. The NASA Magnetospheric Multiscale (MMS) mission, capable of resolving sub-gyroscales of both electrons and ions, has created new frontiers in the state-of-the-art understanding of the diffusion region. The MMS detection of reconnection at Earth's magnetopause will be discussed to highlight the roles of demagnetized particle orbits and wave fluctuations in the reconnection dynamics. When the guide field is significantly weaker than the reconnecting magnetic field, the reconnection current layer is gyro-resistive and the electron distribution functions exhibit strong finite-gyroradius effects with crescent and counterstreaming characteristics. When the guide field is comparable to the reconnecting component, the electron jets are mainly the E cross B drift due to the polarization electric field and the guide magnetic field, and the energy conversion at the jet reversal is dominated by the wave electric field near the lower hybrid frequency. Insensitive to the guide-field, the dense magnetosheath electrons in the reconnection exhaust are transported, by wave turbulence, across the magnetospheric separatrix to modify the plasma properties and field structures in the magnetosphere. The MMS results will be compared with available laboratory measurements from the Magnetic Reconnection Experiment in Princeton, and challenges in diffusion region physics will be discussed. The MMS and MRX teams are acknowledged. Work is supported by NASA, DOE, and NSF.

Localized Electron Heating by Strong Guide-Field Magnetic Reconnection

NASA Astrophysics Data System (ADS)

Guo, Xuehan; Sugawara, Takumichi; Inomoto, Michiaki; Yamasaki, Kotaro; Ono, Yasushi; UTST Team

2015-11-01

Localized electron heating of magnetic reconnection was studied under strong guide-field (typically Bt 15Bp) using two merging spherical tokamak plasmas in Univ. Tokyo Spherical Tokamak (UTST) experiment. Our new slide-type two-dimensional Thomson scattering system documented for the first time the electron heating localized around the X-point. The region of high electron temperature, which is perpendicular to the magnetic field, was found to have a round shape with radius of 2 [cm]. Also, it was localized around the X-point and does not agree with that of energy dissipation term Et .jt . When we include a guide-field effect term Bt / (Bp + αBt) for Et .jt where α =√{ (vin2 +vout2) /v∥2 } , the energy dissipation area becomes localized around the X-point, suggesting that the electrons are accelerated by the reconnection electric field parallel to the magnetic field and thermalized around the X-point. This work was supported by JSPS A3 Foresight Program ``Innovative Tokamak Plasma Startup and Current Drive in Spherical Torus,'' a Grant-in-Aid from the Japan Society for the Promotion of Science (JSPS) Fellows 15J03758.

Electron diffusion region during magnetopause reconnection with an intermediate guide field: Magnetospheric multiscale observations

NASA Astrophysics Data System (ADS)

Chen, L.-J.; Hesse, M.; Wang, S.; Gershman, D.; Ergun, R. E.; Burch, J.; Bessho, N.; Torbert, R. B.; Giles, B.; Webster, J.; Pollock, C.; Dorelli, J.; Moore, T.; Paterson, W.; Lavraud, B.; Strangeway, R.; Russell, C.; Khotyaintsev, Y.; Lindqvist, P.-A.; Avanov, L.

2017-05-01

An electron diffusion region (EDR) in magnetic reconnection with a guide magnetic field approximately 0.2 times the reconnecting component is encountered by the four Magnetospheric Multiscale spacecraft at the Earth's magnetopause. The distinct substructures in the EDR on both sides of the reconnecting current sheet are visualized with electron distribution functions that are 2 orders of magnitude higher cadence than ever achieved to enable the following new findings: (1) Motion of the demagnetized electrons plays an important role to sustain the reconnection current and contributes to the dissipation due to the nonideal electric field, (2) the finite guide field dominates over the Hall magnetic field in an electron-scale region in the exhaust and modifies the electron flow dynamics in the EDR, (3) the reconnection current is in part carried by inflowing field-aligned electrons in the magnetosphere part of the EDR, and (4) the reconnection electric field measured by multiple spacecraft is uniform over at least eight electron skin depths and corresponds to a reconnection rate of approximately 0.1. The observations establish the first look at the structure of the EDR under a weak but not negligible guide field.

E-beam ionized channel guiding of an intense relativistic electron beam

DOEpatents

Frost, C.A.; Godfrey, B.B.; Kiekel, P.D.; Shope, S.L.

1988-05-10

An IREB is guided through a curved path by ionizing a channel in a gas with electrons from a filament, and confining the electrons to the center of the path with a magnetic field extending along the path. The magnetic field is preferably generated by a solenoid extending along the path. 2 figs.

Optical properties of antiferromagnetic/ion-crystal superlattices

NASA Astrophysics Data System (ADS)

Ta, Jin-Xing; Song, Yu-Ling; Wang, Xuan-Zhang

2012-01-01

Transmission, refraction and absorption properties of an antiferromagnetic/ion-crystal superlattice are investigated. The transmission spectra based on FeF2/TlBr superlattices reveal that there exist two intriguing guided modes in a wide stop band. Additionally, FeF2/TlBr superlattices possess either the negative refraction or the quasi left-handedness, or even simultaneously hold them at certain frequencies of two guided modes, which require both negative magnetic permeability of antiferromagnetic layers and negative permittivity of ion-crystal layers. Frequency regimes of the guided modes will be dependent on the magnitude of the external magnetic field. Therefore, handedness and refraction properties of the system can be manipulated by modifying the external magnetic field. Absorption spectra exhibit that absorption corresponding to guided modes is noticeable.

Studies of aggregated nanoparticles steering during magnetic-guided drug delivery in the blood vessels

NASA Astrophysics Data System (ADS)

Hoshiar, Ali Kafash; Le, Tuan-Anh; Amin, Faiz Ul; Kim, Myeong Ok; Yoon, Jungwon

2017-04-01

Magnetic-guided targeted drug delivery (TDD) systems can enhance the treatment of diverse diseases. Despite the potential and promising results of nanoparticles, aggregation prevents precise particle guidance in the vasculature. In this study, we developed a simulation platform to investigate aggregation during steering of nanoparticles using a magnetic field function. The magnetic field function (MFF) comprises a positive and negative pulsed magnetic field generated by electromagnetic coils, which prevents adherence of particles to the vessel wall during magnetic guidance. A commonly used Y-shaped vessel was simulated and the performance of the MFF analyzed; the experimental data were in agreement with the simulation results. Moreover, the effects of various parameters on magnetic guidance were evaluated and the most influential identified. The simulation results presented herein will facilitate more precise guidance of nanoparticles in vivo.

Multimodal magnetic nano-carriers for cancer treatment: Challenges and advancements

NASA Astrophysics Data System (ADS)

Aadinath, W.; Ghosh, Triroopa; Anandharamakrishnan, C.

2016-03-01

Iron oxide nanoparticles (IONPs) have been a propitious topic for cancer treatment in recent years because of its multifunctional theranostic applications under magnetic field. Two such widely used applications in cancer biology are gradient magnetic field guided targeting and alternative magnetic field (AMF) induced local hyperthermia. Gradient magnetic field guided targeting is a mode of active targeting of therapeutics conjugated with iron oxide nanoparticles. These particles also dissipate heat in presence of AMF which causes thermal injury to the cells of interest, for example tumour cells and subsequent death. Clinical trials divulge the feasibility of such magnetic nano-carrier as a promising candidate in cancer biology. However, these techniques need further investigations to curtail certain limitations manifested. Recent progresses in response have shrunken the barricade to certain extent. In this context, principles, challenges associated with these applications and recent efforts made in response will be discussed.

Dosimetric feasibility of real-time MRI-guided proton therapy

PubMed Central

Moteabbed, M.; Schuemann, J.; Paganetti, H.

2014-01-01

Purpose: Magnetic resonance imaging (MRI) is a prime candidate for image-guided radiotherapy. This study was designed to assess the feasibility of real-time MRI-guided proton therapy by quantifying the dosimetric effects induced by the magnetic field in patients’ plans and identifying the associated clinical consequences. Methods: Monte Carlo dose calculation was performed for nine patients of various treatment sites (lung, liver, prostate, brain, skull-base, and spine) and tissue homogeneities, in the presence of 0.5 and 1.5 T magnetic fields. Dose volume histogram (DVH) parameters such as D95, D5, and V20 as well as equivalent uniform dose were compared for the target and organs at risk, before and after applying the magnetic field. The authors further assessed whether the plans affected by clinically relevant dose distortions could be corrected independent of the planning system. Results: By comparing the resulting dose distributions and analyzing the respective DVHs, it was determined that despite the observed lateral beam deflection, for magnetic fields of up to 0.5 T, neither was the target coverage jeopardized nor was the dose to the nearby organs increased in all cases except for prostate. However, for a 1.5 T magnetic field, the dose distortions were more pronounced and of clinical concern in all cases except for spine. In such circumstances, the target was severely underdosed, as indicated by a decrease in D95 of up to 41% of the prescribed dose compared to the nominal situation (no magnetic field). Sites such as liver and spine were less affected due to higher tissue homogeneity, typically smaller beam range, and the choice of beam directions. Simulations revealed that small modifications to certain plan parameters such as beam isocenter (up to 19 mm) and gantry angle (up to 10°) are sufficient to compensate for the magnetic field-induced dose disturbances. The authors’ observations indicate that the degree of required corrections strongly depends on the beam range and direction relative to the magnetic field. This method was also applicable to more heterogeneous scenarios such as skull-base tumors. Conclusions: This study confirmed the dosimetric feasibility of real-time MRI-guided proton therapy and delivering a clinically acceptable dose to patients with various tumor locations within magnetic fields of up to 1.5 T. This work could serve as a guide and encouragement for further efforts toward clinical implementation of hybrid MRI–proton gantry systems. PMID:25370627

Dosimetric feasibility of real-time MRI-guided proton therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moteabbed, M., E-mail: mmoteabbed@partners.org; Schuemann, J.; Paganetti, H.

2014-11-01

Purpose: Magnetic resonance imaging (MRI) is a prime candidate for image-guided radiotherapy. This study was designed to assess the feasibility of real-time MRI-guided proton therapy by quantifying the dosimetric effects induced by the magnetic field in patients’ plans and identifying the associated clinical consequences. Methods: Monte Carlo dose calculation was performed for nine patients of various treatment sites (lung, liver, prostate, brain, skull-base, and spine) and tissue homogeneities, in the presence of 0.5 and 1.5 T magnetic fields. Dose volume histogram (DVH) parameters such as D{sub 95}, D{sub 5}, and V{sub 20} as well as equivalent uniform dose were comparedmore » for the target and organs at risk, before and after applying the magnetic field. The authors further assessed whether the plans affected by clinically relevant dose distortions could be corrected independent of the planning system. Results: By comparing the resulting dose distributions and analyzing the respective DVHs, it was determined that despite the observed lateral beam deflection, for magnetic fields of up to 0.5 T, neither was the target coverage jeopardized nor was the dose to the nearby organs increased in all cases except for prostate. However, for a 1.5 T magnetic field, the dose distortions were more pronounced and of clinical concern in all cases except for spine. In such circumstances, the target was severely underdosed, as indicated by a decrease in D{sub 95} of up to 41% of the prescribed dose compared to the nominal situation (no magnetic field). Sites such as liver and spine were less affected due to higher tissue homogeneity, typically smaller beam range, and the choice of beam directions. Simulations revealed that small modifications to certain plan parameters such as beam isocenter (up to 19 mm) and gantry angle (up to 10°) are sufficient to compensate for the magnetic field-induced dose disturbances. The authors’ observations indicate that the degree of required corrections strongly depends on the beam range and direction relative to the magnetic field. This method was also applicable to more heterogeneous scenarios such as skull-base tumors. Conclusions: This study confirmed the dosimetric feasibility of real-time MRI-guided proton therapy and delivering a clinically acceptable dose to patients with various tumor locations within magnetic fields of up to 1.5 T. This work could serve as a guide and encouragement for further efforts toward clinical implementation of hybrid MRI–proton gantry systems.« less

The effect of grading the atomic number at resistive guide element interface on magnetic collimation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alraddadi, R. A. B.; Woolsey, N. C.; Robinson, A. P. L.

2016-07-15

Using 3 dimensional numerical simulations, this paper shows that grading the atomic number and thus the resistivity at the interface between an embedded high atomic number guide element and a lower atomic number substrate enhances the growth of a resistive magnetic field. This can lead to a large integrated magnetic flux density, which is fundamental to confining higher energy fast electrons. This results in significant improvements in both magnetic collimation and fast-electron-temperature uniformity across the guiding. The graded interface target provides a method for resistive guiding that is tolerant to laser pointing.

Monte Carlo study of the impact of a magnetic field on the dose distribution in MRI-guided HDR brachytherapy using Ir-192

NASA Astrophysics Data System (ADS)

Beld, E.; Seevinck, P. R.; Lagendijk, J. J. W.; Viergever, M. A.; Moerland, M. A.

2016-09-01

In the process of developing a robotic MRI-guided high-dose-rate (HDR) prostate brachytherapy treatment, the influence of the MRI scanner’s magnetic field on the dose distribution needs to be investigated. A magnetic field causes a deflection of electrons in the plane perpendicular to the magnetic field, and it leads to less lateral scattering along the direction parallel with the magnetic field. Monte Carlo simulations were carried out to determine the influence of the magnetic field on the electron behavior and on the total dose distribution around an Ir-192 source. Furthermore, the influence of air pockets being present near the source was studied. The Monte Carlo package Geant4 was utilized for the simulations. The simulated geometries consisted of a simplified point source inside a water phantom. Magnetic field strengths of 0 T, 1.5 T, 3 T, and 7 T were considered. The simulation results demonstrated that the dose distribution was nearly unaffected by the magnetic field for all investigated magnetic field strengths. Evidence was found that, from a dose perspective, the HDR prostate brachytherapy treatment using Ir-192 can be performed safely inside the MRI scanner. No need was found to account for the magnetic field during treatment planning. Nevertheless, the presence of air pockets in close vicinity to the source, particularly along the direction parallel with the magnetic field, appeared to be an important point for consideration.

Monte Carlo study of the impact of a magnetic field on the dose distribution in MRI-guided HDR brachytherapy using Ir-192.

PubMed

Beld, E; Seevinck, P R; Lagendijk, J J W; Viergever, M A; Moerland, M A

2016-09-21

In the process of developing a robotic MRI-guided high-dose-rate (HDR) prostate brachytherapy treatment, the influence of the MRI scanner's magnetic field on the dose distribution needs to be investigated. A magnetic field causes a deflection of electrons in the plane perpendicular to the magnetic field, and it leads to less lateral scattering along the direction parallel with the magnetic field. Monte Carlo simulations were carried out to determine the influence of the magnetic field on the electron behavior and on the total dose distribution around an Ir-192 source. Furthermore, the influence of air pockets being present near the source was studied. The Monte Carlo package Geant4 was utilized for the simulations. The simulated geometries consisted of a simplified point source inside a water phantom. Magnetic field strengths of 0 T, 1.5 T, 3 T, and 7 T were considered. The simulation results demonstrated that the dose distribution was nearly unaffected by the magnetic field for all investigated magnetic field strengths. Evidence was found that, from a dose perspective, the HDR prostate brachytherapy treatment using Ir-192 can be performed safely inside the MRI scanner. No need was found to account for the magnetic field during treatment planning. Nevertheless, the presence of air pockets in close vicinity to the source, particularly along the direction parallel with the magnetic field, appeared to be an important point for consideration.

Preliminary research on overmoded high-power millimeter-wave Cerenkov generator with dual-cavity reflector in low guiding magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ye, Hu; Wu, Ping; Science and Technology on High Power Microwave Laboratory, Northwest Institute of Nuclear Technology, Xi'an, Shaanxi 710024

2015-12-15

This paper presents preliminary research on a V-band overmoded Cerenkov generator with dual-cavity reflector operating in a low guiding magnetic field. It is found that the fluctuation of the electron envelope in the low guiding magnetic field can be predicted using an equivalent coaxial model of a foilless diode, and a dual-cavity reflector based on the model matching method can provide strong reflection at the front end of the overmoded structures so that any microwave power that leaks into the diode region can be effectively suppressed. Numerical simulations indicate that the control of the beam envelope and the use ofmore » the dual-cavity reflector ease generator operation in the low guiding magnetic field. In the experimental research, the fluctuation of the annular electron beam with the outer radius of 7.5 mm measures approximately 0.7 mm, which is in good agreement with the theoretical results. The disturbance caused by power leaking from the overmoded slow wave structure is eliminated by the dual-cavity reflector. With accurate fabrication and assembly processes, an operating frequency of 61.6 GHz is attained by the fifth harmonic heterodyne method, and the output power is measured to be approximately 123 MW by the far-field measurement method at a diode voltage of 445 kV, a beam current of 4.45 kA, and under a guiding magnetic field of 1.45 T. The output mode is measured using an array of neon flash bulbs, and the pulse shortening phenomenon is both observed and analyzed.« less

Gantry for medical particle therapy facility

DOEpatents

Trbojevic, Dejan

2013-04-23

A particle therapy gantry for delivering a particle beam to a patient includes a beam tube having a curvature defining a particle beam path and a plurality of superconducting, variable field magnets sequentially arranged along the beam tube for guiding the particle beam along the particle path. In a method for delivering a particle beam to a patient through a gantry, a particle beam is guided by a plurality of variable field magnets sequentially arranged along a beam tube of the gantry and the beam is alternately focused and defocused with alternately arranged focusing and defocusing variable field magnets.

Gantry for medical particle therapy facility

DOEpatents

Trbojevic, Dejan [Wading River, NY

2012-05-08

A particle therapy gantry for delivering a particle beam to a patient includes a beam tube having a curvature defining a particle beam path and a plurality of fixed field magnets sequentially arranged along the beam tube for guiding the particle beam along the particle path. In a method for delivering a particle beam to a patient through a gantry, a particle beam is guided by a plurality of fixed field magnets sequentially arranged along a beam tube of the gantry and the beam is alternately focused and defocused with alternately arranged focusing and defocusing fixed field magnets.

Computational Studies of Magnetic Nozzle Performance

NASA Technical Reports Server (NTRS)

Ebersohn, Frans H.; Longmier, Benjamin W.; Sheehan, John P.; Shebalin, John B.; Raja, Laxminarayan

2013-01-01

An extensive literature review of magnetic nozzle research has been performed, examining previous work, as well as a review of fundamental principles. This has allow us to catalog all basic physical mechanisms which we believe underlie the thrust generation process. Energy conversion mechanisms include the approximate conservation of the magnetic moment adiabatic invariant, generalized hall and thermoelectric acceleration, swirl acceleration, thermal energy transformation into directed kinetic energy, and Joule heating. Momentum transfer results from the interaction of the applied magnetic field with currents induced in the plasma plume., while plasma detachment mechanisms include resistive diffusion, recombination and charge exchange collisions, magnetic reconnection, loss of adiabaticity, inertial forces, current closure, and self-field detachment. We have performed a preliminary study of Hall effects on magnetic nozzle jets with weak guiding magnetic fields and weak expansions (p(sub jet) approx. = P(sub background)). The conclusion from this study is that the Hall effect creates an azimuthal rotation of the plasma jet and, more generally, creates helical structures in the induced current, velocity field, and magnetic fields. We have studied plasma jet expansion to near vacuum without a guiding magnetic field, and are presently including a guiding magnetic field using a resistive MHD solver. This research is progressing toward the implementation of a full generalized Ohm's law solver. In our paper, we will summarize the basic principle, as well as the literature survey and briefly review our previous results. Our most recent results at the time of submittal will also be included. Efforts are currently underway to construct an experiment at the University of Michigan Plasmadynamics and Electric Propulsion Laboratory (PEPL) to study magnetic nozzle physics for a RF-thruster. Our computational study will work directly with this experiment to validate the numerical model, in order to study magnetic nozzle physics and optimize magnetic nozzle design. Preliminary results from the PEPL experiment will also be presented.

Theoretical predictions for spatially-focused heating of magnetic nanoparticles guided by magnetic particle imaging field gradients

NASA Astrophysics Data System (ADS)

Dhavalikar, Rohan; Rinaldi, Carlos

2016-12-01

Magnetic nanoparticles in alternating magnetic fields (AMFs) transfer some of the field's energy to their surroundings in the form of heat, a property that has attracted significant attention for use in cancer treatment through hyperthermia and in developing magnetic drug carriers that can be actuated to release their cargo externally using magnetic fields. To date, most work in this field has focused on the use of AMFs that actuate heat release by nanoparticles over large regions, without the ability to select specific nanoparticle-loaded regions for heating while leaving other nanoparticle-loaded regions unaffected. In parallel, magnetic particle imaging (MPI) has emerged as a promising approach to image the distribution of magnetic nanoparticle tracers in vivo, with sub-millimeter spatial resolution. The underlying principle in MPI is the application of a selection magnetic field gradient, which defines a small region of low bias field, superimposed with an AMF (of lower frequency and amplitude than those normally used to actuate heating by the nanoparticles) to obtain a signal which is proportional to the concentration of particles in the region of low bias field. Here we extend previous models for estimating the energy dissipation rates of magnetic nanoparticles in uniform AMFs to provide theoretical predictions of how the selection magnetic field gradient used in MPI can be used to selectively actuate heating by magnetic nanoparticles in the low bias field region of the selection magnetic field gradient. Theoretical predictions are given for the spatial decay in energy dissipation rate under magnetic field gradients representative of those that can be achieved with current MPI technology. These results underscore the potential of combining MPI and higher amplitude/frequency actuation AMFs to achieve selective magnetic fluid hyperthermia (MFH) guided by MPI.

Magnetic guide-wire navigation in pulmonary and systemic arterial catheterization: initial experience in pigs.

PubMed

Grosse-Wortmann, Lars; Grabitz, Ralf; Seghaye, Marie-Christine

2007-04-01

Cardiovascular catheterization can be challenging whenever a stenosis or an abnormal vascular course interferes with probing the target vessel. This study addresses the feasibility of navigating a guide wire with a magnetic tip by an external magnetic field through pulmonary and systemic arteries in an experimental porcine model. We investigated six piglets using magnetic guide-wire navigation. Two pulmonary arteriograms were taken from different angles in order to reconstruct the three-dimensional vessel anatomy. A computer interface then calculated three-dimensional coordinates for the vessel in space. Using these coordinates, two external magnets were positioned to create magnetic vectors along the expected vessel course. Magnetically enabled guide wires were then navigated into the vessels using the magnetic field to orient the guide-wire tips. Aortic and renal branches were addressed in a similar fashion. Difficulty in reaching the target vessel was reflected by the number of attempts that were necessary. After 10 failed attempts, the maneuver was recorded to have failed. Thirty-five of 37 (94.6%) arteries with branches at acute angles were reached successfully using magnetic navigation. In two pigs, the left upper lobe artery could not be probed. Peripheral arteries of small diameter were easier to reach than large central arteries, requiring less attempts. Magnetic guide-wire navigation is feasible in the arteries of the lungs, the head and neck, and the kidneys. It is particularly useful in entering small arterial branches at acute angles and may facilitate interventional therapy in a variety of vascular diseases in children and adults.

Turbulent magnetic fluctuations in laboratory reconnection

NASA Astrophysics Data System (ADS)

Von Stechow, Adrian; Grulke, Olaf; Klinger, Thomas

2016-07-01

The role of fluctuations and turbulence is an important question in astrophysics. While direct observations in space are rare and difficult dedicated laboratory experiments provide a versatile environment for the investigation of magnetic reconnection due to their good diagnostic access and wide range of accessible plasma parameters. As such, they also provide an ideal chance for the validation of space plasma reconnection theories and numerical simulation results. In particular, we studied magnetic fluctuations within reconnecting current sheets for various reconnection parameters such as the reconnection rate, guide field, as well as plasma density and temperature. These fluctuations have been previously interpreted as signatures of current sheet plasma instabilities in space and laboratory systems. Especially in low collisionality plasmas these may provide a source of anomalous resistivity and thereby contribute a significant fraction of the reconnection rate. We present fluctuation measurements from two complementary reconnection experiments and compare them to numerical simulation results. VINETA.II (Greifswald, Germany) is a cylindrical, high guide field reconnection experiment with an open field line geometry. The reconnecting current sheet has a three-dimensional structure that is predominantly set by the magnetic pitch angle which results from the superposition of the guide field and the in-plane reconnecting field. Within this current sheet, high frequency magnetic fluctuations are observed that correlate well with the local current density and show a power law spectrum with a spectral break at the lower hybrid frequency. Their correlation lengths are found to be extremely short, but propagation is nonetheless observed with high phase velocities that match the Whistler dispersion. To date, the experiment has been run with an external driving field at frequencies higher than the ion cyclotron frequency f_{ci}, which implies that the EMHD framework applies. Recent machine upgrades allow the inclusion of ion dynamics by reducing the drive frequency below f_{ci}. Two numerical codes (EMHD and hybrid, respectively) have been developed at the Max Planck Institute for solar physics and are used to investigate instability mechanisms and scaling laws for the observed results. MRX (PPPL. Princeton) is a zero to medium guide field, toroidal reconnection experiment. Despite the differing plasma parameters, the qualitative magnetic fluctuation behavior (amplitude profiles, spectra and propagation properties) is comparable to VINETA.II. Results from a new measurement campaign at several different guide fields provides partial overlap with VINETA.II guide field ratios and thereby extends the accessible parameter space of our studies.

SU-E-J-201: Investigation of MRI Guided Proton Therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, JS

2015-06-15

Purpose: Image-guided radiation therapy has been employed for cancer treatment to improve the tumor localization accuracy. Radiation therapy with proton beams requires more on this accuracy because the proton beam has larger uncertainty and dramatic dose variation along the beam direction. Among all the image modalities, magnetic-resonance image (MRI) is the best for soft tissue delineation and real time motion monitoring. In this work, we investigated the behavior of the proton beam in magnetic field with Monte Carlo simulations. Methods: A proton Monte Carlo platform, TOPAS, was used for this investigation. Dose calculations were performed with this platform in amore » 30cmx30cmx30cm water phantom for both pencil and broad proton beams with different energies (120, 150 and 180MeV) in different magnetic fields (0.5T, 1T and 3T). The isodose distributions, dose profiles in lateral and beam direction were evaluated. The shifts of the Bragg peak in different magnetic fields for different proton energies were compared and the magnetic field effects on the characters of the dose distribution were analyzed. Results: Significant effects of magnetic field have been observed on the proton beam dose distributions, especially for magnetic field of 1T and up. The effects are more significant for higher energy proton beam because higher energy protons travel longer distance in the magnetic field. The Bragg peak shift in the lateral direction is about 38mm for 180MeV and 11mm for 120MeV proton beams in 3T magnetic field. The peak positions are retracted back for 6mm and 2mm, respectively. The effect on the beam penumbra and dose falloff at the distal edge of the Bragg peak is negligible. Conclusion: Though significant magnetic effects on dose distribution have been observed for proton beams, MRI guided proton therapy is feasible because the magnetic effects on dose is predictable and can be considered in patient dose calculation.« less

Energization and Transport in 3D Kinetic Simulations of MMS Magnetopause Reconnection Site Encounters with Varying Guide Fields

NASA Astrophysics Data System (ADS)

Le, A.; Daughton, W. S.; Ohia, O.; Chen, L. J.; Liu, Y. H.

2017-12-01

We present 3D fully kinetic simulations of asymmetric reconnection with plasma parameters matching MMS magnetopause diffusion region crossings with varying guide fields of 0.1 [Burch et al., Science (2016)], 0.4 [Chen et al. JGR (2017)], and 1 [Burch and Phan, GRL (2016] of the reconnecting sheath field. Strong diamagnetic drifts across the magnetopause current sheet drive lower-hybrid drift instabilities (LHDI) over a range of wavelengths [Daughton, PoP (2003); Roytershteyn et al., PRL (2012)] that develop into a turbulent state. Magnetic field tracing diagnostics are employed to characterize the turbulent magnetic geometry and to evaluate the global reconnection rate. The contributions to Ohm's law are evaluated field line by field line, including time-averaged diagnostics that allow the quantification of anomalous resistivity and viscosity. We examine how fluctuating electric fields and chaotic magnetic field lines contribute to particle mixing across the separatrix, and we characterize the accelerated electron distributions that form under varying magnetic shear or guide field. The LHDI turbulence is found to strongly enhance transport and parallel electron heating in 3D compared to 2D, particularly along the magnetospheric separatrix [Le et al., GRL (2017)]. The PIC simulation results are compared to MMS observations.

Safety of High Speed Guided Ground Transportation Systems. Broadband Magnetic Fields : Their Possible Role in EMF Associated Bioeffects

DOT National Transportation Integrated Search

1993-08-01

This report reviews electric and magnetic field (EMF) exposures from electrical transportation systems, including : electrically powered rail and magnetic levitation (maglev). Material also covered includes research concerning : biological effects of...

Discontinuous finite element space-angle treatment of the first order linear Boltzmann transport equation with magnetic fields: Application to MRI-guided radiotherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

St Aubin, J., E-mail: joel.st.aubin@albertahealthservices.ca; Keyvanloo, A.; Fallone, B. G.

Purpose: The advent of magnetic resonance imaging (MRI) guided radiotherapy systems demands the incorporation of the magnetic field into dose calculation algorithms of treatment planning systems. This is due to the fact that the Lorentz force of the magnetic field perturbs the path of the relativistic electrons, hence altering the dose deposited by them. Building on the previous work, the authors have developed a discontinuous finite element space-angle treatment of the linear Boltzmann transport equation to accurately account for the effects of magnetic fields on radiotherapy doses. Methods: The authors present a detailed description of their new formalism and comparemore » its accuracy to GEANT4 Monte Carlo calculations for magnetic fields parallel and perpendicular to the radiation beam at field strengths of 0.5 and 3 T for an inhomogeneous 3D slab geometry phantom comprising water, bone, and air or lung. The accuracy of the authors’ new formalism was determined using a gamma analysis with a 2%/2 mm criterion. Results: Greater than 98.9% of all points analyzed passed the 2%/2 mm gamma criterion for the field strengths and orientations tested. The authors have benchmarked their new formalism against Monte Carlo in a challenging radiation transport problem with a high density material (bone) directly adjacent to a very low density material (dry air at STP) where the effects of the magnetic field dominate collisions. Conclusions: A discontinuous finite element space-angle approach has been proven to be an accurate method for solving the linear Boltzmann transport equation with magnetic fields for cases relevant to MRI guided radiotherapy. The authors have validated the accuracy of this novel technique against GEANT4, even in cases of strong magnetic field strengths and low density air.« less

Beyond 2D: Parallel Electric Fields and Dissipation in Guide Field Reconnectio

NASA Astrophysics Data System (ADS)

Wilder, F. D.; Ergun, R.; Ahmadi, N.; Goodrich, K.; Eriksson, S.; Shimoda, E.; Burch, J. L.; Phan, T.; Torbert, R. B.; Strangeway, R. J.; Giles, B. L.; Lindqvist, P. A.; Khotyaintsev, Y. V.

2017-12-01

In 2015, NASA launched the Magnetospheric Multiscale (MMS) mission to study phenomenon of magnetic reconnection down to the electron scale. Advantages of MMS include a 20s spin period and long axial booms, which together allow for measurement of 3-D electric fields with accuracy down to 1 mV/m. During the two dayside phases of the prime mission, MMS has observed multiple electron and ion diffusion region events at the Earth's subsolar and flank magnetopause, as well as in the magnetosheath, providing an option to study both symmetric and asymmetric reconnection at a variety of guide field strengths. We present a review of parallel electric fields observed by MMS during diffusion region events, and discuss their implications for simulations and laboratory observations of reconnection. We find that as the guide field increases, the dissipation in the diffusion region transitions from being due to currents and fields perpendicular to the background magnetic field, to being associated with parallel electric fields and currents. Additionally, the observed parallel electric fields are significantly larger than those predicted by simulations of reconnection under strong guide field conditions.

Sub-solar Magnetopause Observation and Simulation of a Tripolar Guide-Magnetic Field Perturbation

NASA Astrophysics Data System (ADS)

Eriksson, S.; Cassak, P.; Retino, A.; Mozer, F.

2015-12-01

The Polar satellite recorded two reconnection exhausts within 6 min on 1 April 2001 at a rather symmetric sub-solar magnetopause that displayed different out-of-plane signatures for similar solar wind conditions. The first case was reported by Mozer et al. [2002] and displayed a bipolar guide field supporting a quadrupole Hall field consistent with a single X-line. The second case, however, shows the first known example of a tripolar guide-field perturbation at Earth's magnetopause reminiscent of the types of solar wind exhausts that Eriksson et al. [2014; 2015] have reported to be in agreement with multiple X-lines. A dedicated particle-in-cell simulation is performed for the prevailing conditions across the magnetopause. We propose an explanation in terms of asymmetric Hall magnetic fields due to a presence of a magnetic island between two X-lines, and discuss how higher resolution MMS observations can be used to further study this problem at the magnetopause.

Analytical model for fast reconnection in large guide field plasma configurations

NASA Astrophysics Data System (ADS)

Simakov, A. N.; Chacón, L.; Grasso, D.; Borgogno, D.; Zocco, A.

2009-11-01

Significant progress in understanding magnetic reconnection without a guide field was made recently by deriving quantitatively accurate analytical models for reconnection in electron [1] and Hall [2] MHD. However, no such analytical model is available for reconnection with a guide field. Here, we derive such an analytical model for the large-guide-field, low-β, cold-ion fluid model [3] with electron inertia, ion viscosity μ, and resistivity η. We find that the reconnection is Sweet-Parker-like when the Sweet-Parker layer thickness δSP> (ρs^4 + de^4)^1/4, with ρs and de the sound Larmor radius and electron inertial length. However, reconnection changes character otherwise, resulting in reconnection rates Ez/Bx^2 √2 η/μ (ρs^2 + de^2)/(ρsw) with Bx the upstream magnetic field and w the diffusion region length. Unlike the zero-guide-field case, μ plays crucial role in manifesting fast reconnection rates. If it represents the perpendicular viscosity [3], √η/μ ˜&-1circ;√(me/mi)(Ti/Te) and Ez becomes dissipation independent and therefore potentially fast.[0pt] [1] L. Chac'on, A. N. Simakov, and A. Zocco, PRL 99, 235001 (2007).[0pt] [2] A. N. Simakov and L. Chac'on, PRL 101, 105003 (2008).[0pt] [3] D. Biskamp, Magnetic reconnection in plasmas, Cambridge University Press, 2000.

Nonthermal Particle Acceleration in Relativistic Collisionless Magnetic Reconnection

NASA Astrophysics Data System (ADS)

Uzdensky, D. A.; Werner, G.; Begelman, M.; Zhdankin, V.

2017-12-01

Recent years have seen significant progress, achieved mostly with particle-in-cell (PIC) simulations, in our understanding of collisionless relativistic magnetic reconnection in both electron-positron pair and electron-ion plasmas, with important implications for high-energy astrophysics. In this talk I will summarize the main findings of a series of systematic PIC studies of reconnection-driven nonthermal particle acceleration (NTPA) in pair plasmas (in both 2D and 3D) and in electron-ion plasmas (in 2D) conducted by our University of Colorado group. We have characterized the nonthermal power-law index α and the high-energy cutoff γ c of the particle energy distribution as functions of system size L, upstream plasma magnetization σ =B02/4π h (where B0 is the reconnecting magnetic field and h is the relativistic plasma enthalpy, including rest-mass), and guide magnetic field Bgz. We have found that, despite the rapid development of 3D drift-kink instability, NTPA is similar in 2D and 3D pair plasmas, producing robust power-law spectra. The power-law index α becomes asymptotically independent of L as L-> ∞ , but exhibits a clear dependence on σ and Bgz. Thus, we find that α decreases with increased σ and approaches a constant value consistent with (but perhaps slightly higher than) 1 in the ultra-relativistic limit σ -> ∞ (without guide field), and increases as one moves into the non-relativistic, low-σ regime. A strong guide field is found to suppress particle acceleration by reducing γ c and increasing α . Overall, our empirical results for both pair and electron-ion plasmas are consistent with α = C1 + C2 σ eff-1/2, where the effective upstream magnetization σ eff includes the guide field's contribution to the total enthalpy, i.e., σ eff = B02/(4π h + Bgz2). In addition, in 2D electron-ion reconnection without guide field, the fraction of the released magnetic energy that goes to the electrons gradually decreases from 50% in the ultra-relativistic high-σ limit to a constant of about 0.25 in the low-σ semi-relativistic limit (ultra-relativistic electrons but nonrelativisitc ions).

TH-AB-BRA-06: MOSFET-Based Dosimetry in An MR Image-Guided Radiation Therapy System: Comparison with and Without a Static 0.3T Magnetic Field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cammin, J; Curcuru, A; Li, H

Purpose: To compare depth-dose and surface-dose measurements without and with the magnetic field in a 0.3T MR image-guided Co-60 treatment unit using MOSFET dosimeters. Methods: MOSFET dosimeters (Best Medical Canada, model TN-502RDH-10) were placed in a solid water phantom at 5cm depth with 8cm backscatter (with the MOSFET wires in different orientations to the couch long axis) and also on the surface of an 8cm solid water phantom. The phantoms were placed in an MR image-guided Co-60 treatment machine at an SAD of 105cm to the MOSFETs. Dose measurements were performed between 50 and 200cGy at 5cm depth in amore » 10.5cm × 10.5cm radiation field without the magnetic field (during a machine maintenance period) and with the nominal magnetic field of 0.3T. The dose linearity was measured at 5cm depth with an orthogonal field and the angular dose dependence was measured on the surface with an orthogonal field and oblique fields at +60 degrees and −60 degrees. Results: The measured MOSFET readings at 5cm depth were linear with dose with slopes of (2.97 +/− 0.01) mV/cGy and (3.01 +/− 0.02) mV/cGy without and with the magnetic field, respectively. No statistically significant difference was found. The surface dose measurements, however, were lower by 6.4% for the AP field (2.3 σ) with magnetic field, 4.9% for the −60 degree field (1.4 σ), and 0.4% different for the +60 degree field (0.2 σ). Conclusion: There is no statistically significant difference in the dose at depth without and with the magnetic field and different orientations of the MOSFET wires. There is a statistically significant difference for the surface dose due to the influence of the magnetic field on secondary electrons from head-scatter and the build-up region in certain field orientations. Clinical surface-dose dosimetry in a magnetic field should apply asymmetric angle-dependent corrections.« less

Francis Bitter National Laboratory quarterly progress report, July 1, 1972--September 30, 1972

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1972-10-31

Reports on research projects at Francis Bitter National Magnet Laboratory are presented on 19 different topics including the following: far infrared magneto-optics; quantum optics; soft x-rays and laser-produced plasmas; magneto-optical theory; magnetism and superconductivity; Mossbauer effect studies; superconducting thin films; amorphous semiconductors and superconductivity; nuclear magnetic resonance of biomolecules; low magnetic fields; superconducting medical magnet; magnetically guided catheters; magnetic separation; high current switching; development of guided electromagnetic flight; Alcator; high voltage discharges in cryocables; and low temperature thermometry in high magnetic fields. The Magnet Research and Technology Program and reports of visiting scientists are also included in this report. Reportsmore » on some research not supported by NSF are included, and the supporting agencies are indicated. A list of publications and speeches presented at meetings during the quarter covered by this report are included in an appendix.« less

Preliminary experimental investigation of an X-band Cerenkov-type high power microwave oscillator without guiding magnetic field.

PubMed

Guo, Liming; Shu, Ting; Li, Zhiqiang; Ju, Jinchuan; Fang, Xiaoting

2017-02-01

Among high power microwave (HPM) generators without guiding magnetic field, Cerenkov-type oscillator is expected to achieve a relatively high efficiency, which has already been realized in X-band in our previous simulation work. This paper presents the preliminary experimental investigations into an X-band Cerenkov-type HPM oscillator without guiding magnetic field. Based on the previous simulation structure, some modifications regarding diode structure were made. Different cathode structures and materials were tested in the experiments. By using a ring-shaped graphite cathode, microwave of about one hundred megawatt level was generated with a pure center frequency of 9.14 GHz, and an efficiency of about 1.3%. As analyzed in the paper, some practical issues reduce the efficiency in experiments, such as real features of the electron beam, probable breakdown regions on the cathode surface which can damage the diode, and so forth.

Impact of compressibility and a guide field on Fermi acceleration during magnetic island coalescence

NASA Astrophysics Data System (ADS)

Montag, P.; Egedal, J.; Lichko, E.; Wetherton, B.

2017-06-01

Previous work has shown that Fermi acceleration can be an effective heating mechanism during magnetic island coalescence, where electrons may undergo repeated reflections as the magnetic field lines contract. This energization has the potential to account for the power-law distributions of particle energy inferred from observations of solar flares. Here, we develop a generalized framework for the analysis of Fermi acceleration that can incorporate the effects of compressibility and non-uniformity along field lines, which have commonly been neglected in previous treatments of the problem. Applying this framework to the simplified case of the uniform flux tube allows us to find both the power-law scaling of the distribution function and the rate at which the power-law behavior develops. We find that a guide magnetic field of order unity effectively suppresses the development of power-law distributions.

Resonant circuit which provides dual frequency excitation for rapid cycling of an electromagnet

DOEpatents

Praeg, Walter F.

1984-01-01

Disclosed is a ring magnet control circuit that permits synchrotron repetition rates much higher than the frequency of the cosinusoidal guide field of the ring magnet during particle acceleration. the control circuit generates cosinusoidal excitation currents of different frequencies in the half waves. During radio frequency acceleration of the particles in the synchrotron, the control circuit operates with a lower frequency cosine wave and thereafter the electromagnets are reset with a higher frequency half cosine wave. Flat-bottom and flat-top wave shaping circuits maintain the magnetic guide field in a relatively time-invariant mode during times when the particles are being injected into the ring magnets and when the particles are being ejected from the ring magnets.

Localized Oscillatory Energy Conversion in Magnetopause Reconnection

NASA Astrophysics Data System (ADS)

Burch, J. L.; Ergun, R. E.; Cassak, P. A.; Webster, J. M.; Torbert, R. B.; Giles, B. L.; Dorelli, J. C.; Rager, A. C.; Hwang, K.-J.; Phan, T. D.; Genestreti, K. J.; Allen, R. C.; Chen, L.-J.; Wang, S.; Gershman, D.; Le Contel, O.; Russell, C. T.; Strangeway, R. J.; Wilder, F. D.; Graham, D. B.; Hesse, M.; Drake, J. F.; Swisdak, M.; Price, L. M.; Shay, M. A.; Lindqvist, P.-A.; Pollock, C. J.; Denton, R. E.; Newman, D. L.

2018-02-01

Data from the NASA Magnetospheric Multiscale mission are used to investigate asymmetric magnetic reconnection at the dayside boundary between the Earth's magnetosphere and the solar wind. High-resolution measurements of plasmas and fields are used to identify highly localized ( 15 electron Debye lengths) standing wave structures with large electric field amplitudes (up to 100 mV/m). These wave structures are associated with spatially oscillatory energy conversion, which appears as alternatingly positive and negative values of J · E. For small guide magnetic fields the wave structures occur in the electron stagnation region at the magnetosphere edge of the electron diffusion region. For larger guide fields the structures also occur near the reconnection X-line. This difference is explained in terms of channels for the out-of-plane current (agyrotropic electrons at the stagnation point and guide field-aligned electrons at the X-line).

Phospholipid micelle-based magneto-plasmonic nanoformulation for magnetic field-directed, imaging-guided photo-induced cancer therapy.

PubMed

Ohulchanskyy, Tymish Y; Kopwitthaya, Atcha; Jeon, Mansik; Guo, Moran; Law, Wing-Cheung; Furlani, Edward P; Kim, Chulhong; Prasad, Paras N

2013-11-01

We present a magnetoplasmonic nanoplatform combining gold nanorods (GNR) and iron-oxide nanoparticles within phospholipid-based polymeric nanomicelles (PGRFe). The gold nanorods exhibit plasmon resonance absorbance at near infrared wavelengths to enable photoacoustic imaging and photothermal therapy, while the Fe3O4 nanoparticles enable magnetophoretic control of the nanoformulation. The fabricated nanoformulation can be directed and concentrated by an external magnetic field, which provides enhancement of a photoacoustic signal. Application of an external field also leads to enhanced uptake of the magnetoplasmonic formulation by cancer cells in vitro. Under laser irradiation at the wavelength of the GNR absorption peak, the PGRFe formulation efficiently generates plasmonic nanobubbles within cancer cells, as visualized by confocal microscopy, causing cell destruction. The combined magnetic and plasmonic functionalities of the nanoplatform enable magnetic field-directed, imaging-guided, enhanced photo-induced cancer therapy. In this study, a nano-formulation of gold nanorods and iron oxide nanoparticles is presented using a phospholipid micelle-based delivery system for magnetic field-directed and imaging-guided photo-induced cancer therapy. The gold nanorods enable photoacoustic imaging and photothermal therapy, while the Fe3O4 nanoparticles enable magnetophoretic control of the formulation. This and similar systems could enable more precise and efficient cancer therapy, hopefully in the near future, after additional testing. Copyright © 2013 Elsevier Inc. All rights reserved.

High temperature superconductor dc-SQUID microscope with a soft magnetic flux guide

NASA Astrophysics Data System (ADS)

Poppe, U.; Faley, M. I.; Zimmermann, E.; Glaas, W.; Breunig, I.; Speen, R.; Jungbluth, B.; Soltner, H.; Halling, H.; Urban, K.

2004-05-01

A scanning SQUID microscope based on high-temperature superconductor (HTS) dc-SQUIDs was developed. An extremely soft magnetic amorphous foil was used to guide the flux from room temperature samples to the liquid-nitrogen-cooled SQUID sensor and back. The flux guide passes through the pick-up loop of the HTS SQUID, providing an improved coupling of magnetic flux of the object to the SQUID. The device measures the z component (direction perpendicular to the sample surface) of the stray field of the sample, which is rastered with submicron precision in the x-y direction by a motorized computer-controlled scanning stage. A lateral resolution better than 10 µm, with a field resolution of about 0.6 nT Hz-1/2 was achieved for the determination of the position of the current carrying thin wires. The presence of the soft magnetic foil did not significantly increase the flux noise of the SQUID.

Magnetic-field-induced dose effects in MR-guided radiotherapy systems: dependence on the magnetic field strength.

PubMed

Raaijmakers, A J E; Raaymakers, B W; Lagendijk, J J W

2008-02-21

Several institutes are currently working on the development of a radiotherapy treatment system with online MR imaging (MRI) modality. The main difference between their designs is the magnetic field strength of the MRI system. While we have chosen a 1.5 Tesla (T) magnetic field strength, the Cross Cancer Institute in Edmonton will be using a 0.2 T MRI scanner and the company Viewray aims to use 0.3 T. The magnetic field strength will affect the severity of magnetic field dose effects, such as the electron return effect (ERE): considerable dose increase at tissue air boundaries due to returning electrons. This paper has investigated how the ERE dose increase depends on the magnetic field strength. Therefore, four situations where the ERE occurs have been simulated: ERE at the distal side of the beam, the lateral ERE, ERE in cylindrical air cavities and ERE in the lungs. The magnetic field comparison values were 0.2, 0.75, 1.5 and 3 T. Results show that, in general, magnetic field dose effects are reduced at lower magnetic field strengths. At the distal side, the ERE dose increase is largest for B = 0.75 T and depends on the irradiation field size for B = 0.2 T. The lateral ERE is strongest for B = 3 T but shows no effect for B = 0.2 T. Around cylindrical air cavities, dose inhomogeneities disappear if the radius of the cavity becomes small relative to the in-air radius of the secondary electron trajectories. At larger cavities (r > 1 cm), dose inhomogeneities exist for all magnetic field strengths. In water-lung-water phantoms, the ERE dose increase takes place at the water-lung transition and the dose decreases at the lung-water transition, but these effects are minimal for B = 0.2 T. These results will contribute to evaluating the trade-off between magnetic field dose effects and image quality of MR-guided radiotherapy systems.

Effects of the reconnection electric field on crescent electron distribution functions in asymmetric guide field reconnection

NASA Astrophysics Data System (ADS)

Bessho, N.; Chen, L. J.; Hesse, M.; Wang, S.

2017-12-01

In asymmetric reconnection with a guide field in the Earth's magnetopause, electron motion in the electron diffusion region (EDR) is largely affected by the guide field, the Hall electric field, and the reconnection electric field. The electron motion in the EDR is neither simple gyration around the guide field nor simple meandering motion across the current sheet. The combined meandering motion and gyration has essential effects on particle acceleration by the in-plane Hall electric field (existing only in the magnetospheric side) and the out-of-plane reconnection electric field. We analyze electron motion and crescent-shaped electron distribution functions in the EDR in asymmetric guide field reconnection, and perform 2-D particle-in-cell (PIC) simulations to elucidate the effect of reconnection electric field on electron distribution functions. Recently, we have analytically expressed the acceleration effect due to the reconnection electric field on electron crescent distribution functions in asymmetric reconnection without a guide field (Bessho et al., Phys. Plasmas, 24, 072903, 2017). We extend the theory to asymmetric guide field reconnection, and predict the crescent bulge in distribution functions. Assuming 1D approximation of field variations in the EDR, we derive the time period of oscillatory electron motion (meandering + gyration) in the EDR. The time period is expressed as a hybrid of the meandering period and the gyro period. Due to the guide field, electrons not only oscillate along crescent-shaped trajectories in the velocity plane perpendicular to the antiparallel magnetic fields, but also move along parabolic trajectories in the velocity plane coplanar with magnetic field. The trajectory in the velocity space gradually shifts to the acceleration direction by the reconnection electric field as multiple bounces continue. Due to the guide field, electron distributions for meandering particles are bounded by two paraboloids (or hyperboloids) in the velocity space. We compare theory and PIC simulation results of the velocity shift of crescent distribution functions based on the derived time period of bounce motion in a guide field. Theoretical predictions are applied to electron distributions observed by MMS in magnetopause reconnection to estimate the reconnection electric field.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jiang Ronglin; Fang Cheng; Shibata, Kazunari

Magnetic reconnection is a fundamental process in space and astrophysical plasmas in which the oppositely directed magnetic field changes its connectivity and eventually converts its energy into kinetic and thermal energy of the plasma. Recently, ubiquitous jets (for example, chromospheric anemone jets, penumbral microjets, umbral light bridge jets) have been observed by the Solar Optical Telescope on board the satellite Hinode. These tiny and frequently occurring jets are considered to be a possible evidence of small-scale ubiquitous reconnection in the solar atmosphere. However, the details of three-dimensional (3D) magnetic configuration are still not very clear. Here, we propose a newmore » model based on 3D simulations of magnetic reconnection using a typical current sheet magnetic configuration with a strong guide field. The most interesting feature is that the jets produced by the reconnection eventually move along the guide field lines. This model provides a fresh understanding of newly discovered ubiquitous jets and moreover a new observational basis for the theory of astrophysical magnetic reconnection.« less

Note: Precise radial distribution of charged particles in a magnetic guiding field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Backe, H., E-mail: backe@kph.uni-mainz.de

2015-07-15

Current high precision beta decay experiments of polarized neutrons, employing magnetic guiding fields in combination with position sensitive and energy dispersive detectors, resulted in a detailed study of the mono-energetic point spread function (PSF) for a homogeneous magnetic field. A PSF describes the radial probability distribution of mono-energetic electrons at the detector plane emitted from a point-like source. With regard to accuracy considerations, unwanted singularities occur as a function of the radial detector coordinate which have recently been investigated by subdividing the radial coordinate into small bins or employing analytical approximations. In this note, a series expansion of the PSFmore » is presented which can numerically be evaluated with arbitrary precision.« less

Numerical studies of the Kelvin-Hemholtz instability in a coronal jet

NASA Astrophysics Data System (ADS)

Zhao, Tian-Le; Ni, Lei; Lin, Jun; Ziegler, Udo

2018-04-01

Kelvin-Hemholtz (K-H) instability in a coronal EUV jet is studied via 2.5D MHD numerical simulations. The jet results from magnetic reconnection due to the interaction of the newly emerging magnetic field and the pre-existing magnetic field in the corona. Our results show that the Alfvén Mach number along the jet is about 5–14 just before the instability occurs, and it is even higher than 14 at some local areas. During the K-H instability process, several vortex-like plasma blobs with high temperature and high density appear along the jet, and magnetic fields have also been rolled up and the magnetic configuration including anti-parallel magnetic fields forms, which leads to magnetic reconnection at many X-points and current sheet fragments inside the vortex-like blob. After magnetic islands appear inside the main current sheet, the total kinetic energy of the reconnection outflows decreases, and cannot support the formation of the vortex-like blob along the jet any longer, then the K-H instability eventually disappears. We also present the results about how the guide field and flux emerging speed affect the K-H instability. We find that a strong guide field inhibits shock formation in the reconnecting upward outflow regions but helps secondary magnetic islands appear earlier in the main current sheet, and then apparently suppresses the K-H instability. As the speed of the emerging magnetic field decreases, the K-H instability appears later, the highest temperature inside the vortex blob gets lower and the vortex structure gets smaller.

Nonlinear evolution of three-dimensional instabilities of thin and thick electron scale current sheets: Plasmoid formation and current filamentation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jain, Neeraj; Büchner, Jörg; Max Planck Institute for Solar System Research, Justus-Von-Liebig-Weg-3, Göttingen

Nonlinear evolution of three dimensional electron shear flow instabilities of an electron current sheet (ECS) is studied using electron-magnetohydrodynamic simulations. The dependence of the evolution on current sheet thickness is examined. For thin current sheets (half thickness =d{sub e}=c/ω{sub pe}), tearing mode instability dominates. In its nonlinear evolution, it leads to the formation of oblique current channels. Magnetic field lines form 3-D magnetic spirals. Even in the absence of initial guide field, the out-of-reconnection-plane magnetic field generated by the tearing instability itself may play the role of guide field in the growth of secondary finite-guide-field instabilities. For thicker current sheetsmore » (half thickness ∼5 d{sub e}), both tearing and non-tearing modes grow. Due to the non-tearing mode, current sheet becomes corrugated in the beginning of the evolution. In this case, tearing mode lets the magnetic field reconnect in the corrugated ECS. Later thick ECS develops filamentary structures and turbulence in which reconnection occurs. This evolution of thick ECS provides an example of reconnection in self-generated turbulence. The power spectra for both the thin and thick current sheets are anisotropic with respect to the electron flow direction. The cascade towards shorter scales occurs preferentially in the direction perpendicular to the electron flow.« less

Atom Skimmers and Atom Lasers Utilizing Them

NASA Technical Reports Server (NTRS)

Hulet, Randall; Tollett, Jeff; Franke, Kurt; Moss, Steve; Sackett, Charles; Gerton, Jordan; Ghaffari, Bita; McAlexander, W.; Strecker, K.; Homan, D.

2005-01-01

Atom skimmers are devices that act as low-pass velocity filters for atoms in thermal atomic beams. An atom skimmer operating in conjunction with a suitable thermal atomic-beam source (e.g., an oven in which cesium is heated) can serve as a source of slow atoms for a magneto-optical trap or other apparatus in an atomic-physics experiment. Phenomena that are studied in such apparatuses include Bose-Einstein condensation of atomic gases, spectra of trapped atoms, and collisions of slowly moving atoms. An atom skimmer includes a curved, low-thermal-conduction tube that leads from the outlet of a thermal atomic-beam source to the inlet of a magneto-optical trap or other device in which the selected low-velocity atoms are to be used. Permanent rare-earth magnets are placed around the tube in a yoke of high-magnetic-permeability material to establish a quadrupole or octupole magnetic field leading from the source to the trap. The atoms are attracted to the locus of minimum magnetic-field intensity in the middle of the tube, and the gradient of the magnetic field provides centripetal force that guides the atoms around the curve along the axis of the tube. The threshold velocity for guiding is dictated by the gradient of the magnetic field and the radius of curvature of the tube. Atoms moving at lesser velocities are successfully guided; faster atoms strike the tube wall and are lost from the beam.

The role of electron heat flux in guide-field magnetic reconnection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hesse, Michael; Kuznetsova, Masha; Birn, Joachim

2004-12-01

A combination of analytical theory and particle-in-cell simulations are employed in order to investigate the electron dynamics near and at the site of guide field magnetic reconnection. A detailed analysis of the contributions to the reconnection electric field shows that both bulk inertia and pressure-based quasiviscous processes are important for the electrons. Analytic scaling demonstrates that conventional approximations for the electron pressure tensor behavior in the dissipation region fail, and that heat flux contributions need to be accounted for. Based on the evolution equation of the heat flux three tensor, which is derived in this paper, an approximate form ofmore » the relevant heat flux contributions to the pressure tensor is developed, which reproduces the numerical modeling result reasonably well. Based on this approximation, it is possible to develop a scaling of the electron current layer in the central dissipation region. It is shown that the pressure tensor contributions become important at the scale length defined by the electron Larmor radius in the guide magnetic field.« less

Laboratory reconnection experiments

NASA Astrophysics Data System (ADS)

Grulke, Olaf

Laboratory experiments dedicated for the study of magnetic reconnection have been contributed considerably to a more detailed understanding of the involved processes. Their strength is to disentangle parameter dependencies, to diagnose in detail the plasma and field response, and to form an excellent testbed for the validation of numerical simulations. In the present paper recent results obtained from the new cylindrical reconnection experiment VINETA II are presented. The experimental setup allows to independently vary plasma parameters, reconnection drive strength/timescale, and current sheet amplitude. Current research objectives focus on two major scientific issues: Guide field effects on magnetic reconnection and the evolution of electromagnetic fluctuations. The superimposed homogeneous magnetic guide field has a strong influence on the spatiotemporal evolution of the current sheet, predominantly due to magnetic pitch angle effects, which leads to a strong elongation of the sheet along the separatrices and results in axial gradients of the reconnection rates. Within the current sheet, incoherent electromagnetic fluctuations are observed. Their magnetic signature is characterized by a broad spectrum somewhat centered around the lower-hybrid frequency and extremely short spatial correlation lengths being typically smaller than the local ion sound radius. The fluctuation amplitude correlates with the local current density and, thus, for low guide fields, displays also axial gradients. Despite the quantitatively different parameter regime and geometry the basic fluctuation properties are in good agreement with studies conducted at the MRX experiment (PPPL).

The modified scheme of optimized in simulations Cherenkov type high-power microwave oscillator without guiding magnetic field

NASA Astrophysics Data System (ADS)

Guo, Li M.; Shu, T.; Li, Zhi Q.; Ju, Jin C.

2017-12-01

The compactness and miniaturization of high-power-microwave (HPM) systems are drawing more and more attention. Based on this demand, HPM generators without a guiding magnetic field are being developed. This paper presents an X-band Cherenkov type HPM oscillator without the guiding magnetic field. By particle-in-cell codes, this oscillator achieves an efficiency of 40% in simulation. When the diode voltage and current are 620 kV and 9.0 kA, respectively, a TEM mode microwave is generated with a power of 2.2 GW and a frequency of 9.1 GHz. In this oscillator, electrons are modulated in both longitudinal and radial directions, and the radial modulation has a significant effect on the energy conversion efficiency. As analyzed in this paper, the different radial modulation effects depend on the phase matching differences of the microwave and electrons. The modified scheme of simulations achieves a structure with an efficient longitudinal beam-wave interaction and optimized radial modulation.

Scaling of Guide-Field Magnetic Reconnection using Anisotropic Fluid Closure

NASA Astrophysics Data System (ADS)

Ohia, O.; Egedal, J.; Lukin, V. S.; Daughton, W.; Le, A.

2012-10-01

Collisionless magnetic reconnection, a process linked to solar flares, coronal mass ejections, and magnetic substorms, has been widely studied through fluid models and fully kinetic simulations. While fluid models often reproduce the fast reconnection rate of fully kinetic simulations, significant differences are observed in the structure of the reconnection regions [1]. However, guide-field fluid simulations implementing new equations of state that accurately account for the anisotropic electron pressure [2] reproduce the detailed reconnection region observed in kinetic simulations [3]. Implementing this two-fluid simulation using the HiFi framework [4], we study the force balance of the electron layers in guide-field reconnection and derive scaling laws for their characteristics.[1ex] [1] Daughton W et al., Phys. Plasmas 13, 072101 (2006).[0ex] [2] Le A et al., Phys. Rev. Lett. 102, 085001 (2009). [0ex] [3] Ohia O, et al., Phys. Rev. Lett. In Press (2012).[0ex] [4] Lukin VS, Linton MG, Nonlinear Proc. Geoph. 18, 871 (2011)

A novel coaxial Ku-band transit radiation oscillator without external guiding magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ling, Junpu, E-mail: lingjunpu@163.com; Zhang, Jiande; He, Juntao

2014-02-15

A novel coaxial transit radiation oscillator without external guiding magnetic field is designed to generate high power microwave at Ku-band. By using a coaxial structure, the space-charge potential energy is suppressed significantly, that is good for enhancing efficient beam-wave interaction. In order to improve the transmission stability of the unmagnetized intense relativistic electron beam, a Pierce-like cathode is employed in the novel device. By contrast with conventional relativistic microwave generators, this kind of device has the advantages of high stability, non-guiding magnetic field, and high efficiency. Moreover, with the coaxial design, it is possible to improve the power-handing capacity bymore » increasing the radial dimension of the Ku-band device. With a 550 keV and 7.5 kA electron beam, a 1.25 GW microwave pulse at 12.08 GHz has been obtained in the simulation. The power conversion efficiency is about 30%.« less

A Monte-Carlo study to assess the effect of 1.5 T magnetic fields on the overall robustness of pencil-beam scanning proton radiotherapy plans for prostate cancer

NASA Astrophysics Data System (ADS)

Kurz, Christopher; Landry, Guillaume; Resch, Andreas F.; Dedes, George; Kamp, Florian; Ganswindt, Ute; Belka, Claus; Raaymakers, Bas W.; Parodi, Katia

2017-11-01

Combining magnetic-resonance imaging (MRI) and proton therapy (PT) using pencil-beam scanning (PBS) may improve image-guided radiotherapy. We aimed at assessing the impact of a magnetic field on PBS-PT plan quality and robustness. Specifically, the robustness against anatomical changes and positioning errors in an MRI-guided scenario with a 30 cm radius 1.5 T magnetic field was studied for prostate PT. Five prostate cancer patients with three consecutive CT images (CT1-3) were considered. Single-field uniform dose PBS-PT plans were generated on the segmented CT1 with Monte-Carlo-based treatment planning software for inverse optimization. Plans were optimized at 90° gantry angle without B-field (no B), with  ±1.5 T B-field (B and minus B), as well as at 81° gantry angle and  +1.5 T (B G81). Plans were re-calculated on aligned CT2 and CT3 to study the impact of anatomical changes. Dose distributions were compared in terms of changes in DVH parameters, proton range and gamma-index pass-rates. To assess the impact of positioning errors, DVH parameters were compared for  ±5 mm CT1 patient shifts in anterior-posterior (AP) and left-right (LR) direction. Proton beam deflection considerably reduced robustness against inter-fractional changes for the B scenario. Range agreement, gamma-index pass-rates and PTV V95% were significantly lower compared to no B. Improved robustness was obtained for minus B and B G81, the latter showing only minor differences to no B. The magnetic field introduced slight dosimetric changes under LR shifts. The impact of AP shifts was considerably larger, and equivalent for scenarios with and without B-field. Results suggest that robustness equivalent to PT without magnetic field can be achieved by adaptation of the treatment parameters, such as B-field orientation (minus B) with respect to the patient and/or gantry angle (B G81). MRI-guided PT for prostate cancer might thus be implemented without compromising robustness compared to state-of-the-art CT-guided PT.

Impact of compressibility and a guide field on Fermi acceleration during magnetic island coalescence

NASA Astrophysics Data System (ADS)

Montag, Peter; Egedal, Jan; Lichko, Emily; Wetherton, Blake

2017-10-01

Previous work has shown that Fermi acceleration can be an effective heating mechanism during magnetic island coalescence, where electrons may undergo repeated reflections as the magnetic field lines contract. This energization has the potential to account for the power-law distributions of particle energy inferred from observations of solar flares. Here, we develop a generalized framework for the analysis of Fermi acceleration that can incorporate the effects of compressibility and non-uniformity along field lines, which have commonly been neglected in previous treatments of the problem. Applying this framework to the simplified case of the uniform flux tube allows us to find both the power-law scaling of the distribution function and the rate at which the power-law behavior develops. We find that a guide magnetic field of order unity effectively suppresses the development of power-law distributions. The work was supported by NASA Grant No. NNX14AC68G, NSF GEM Grant No. 1405166, NSF Award 1404166, and NASA Award NNX15AJ73G.

Magnetic attachment mechanism

NASA Technical Reports Server (NTRS)

Wu, Mitchell B. (Inventor); Harwell, William D. (Inventor)

1988-01-01

A magnetic attachment mechanism adapted for interfacing with the manipulator arm of a remote manipulator system and comprising a pair of permanent magnets of rare earth material are arranged in a stator-rotor relationship. The rotor magnet is journalled for rotation about its longitudinal axis between pole plates of the stator magnet, each of which includes an adhering surface. In a first rotary position corresponding to the ON condition, each of the poles of the rotor magnet is closely adjacent to a stator magnet pole plate of like polarity whereby the respective magnet fields are additive for producing a strong magnetic field emanating from the adhering surfaces for attracting a ferrous magnetic plate, or the like, affixed to the payload. When the rotor magnet is rotated to a second position corresponding to the OFF condition, each of the poles of the rotor magnet is disposed closely adjacent to a pole plate of unlike polarity whereby the magnetic fields of the magnets are in cancelling relationship at the adhering surfaces, which permits the release of a payload. An actuator for selectively rotating the rotor magnet between the ON and OFF positions is provided for interfacing and connecting the magnetic attachment mechanism with a manipulator arm. For affecting an optimal rigidized attachment the payload is provided with guide means cooperable with guide means on the housing of the mechanism for directing adhering surfaces of the polar plates to the ferrous plate.

Design of a high efficiency relativistic backward wave oscillator with low guiding magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Xiaoze; Song, Wei; Tan, Weibing

2016-07-15

A high efficiency relativistic backward wave oscillator working at a low guiding magnetic field is designed and simulated. A trapezoidal resonant reflector is used to reduce the modulation field in the resonant reflector to avoid overmodulation of the electron beam which will lead to a large momentum spread and then low conversion efficiency. The envelope of the inner radius of the slow wave structure (SWS) increases stepwise to keep conformal to the trajectory of the electron beam which will alleviate the bombardment of the electron on the surface of the SWS. The length of period of the SWS is reducedmore » gradually to make a better match between phase velocity and electron beam, which decelerates continually and improves the RF current distribution. Meanwhile the modulation field is reduced by the introduction of nonuniform SWS also. The particle in cell simulation results reveal that a microwave with a power of 1.8 GW and a frequency of 14.7 GHz is generated with an efficiency of 47% when the diode voltage is 620 kV, the beam current 6.1 kA, and the guiding magnetic field 0.95 T.« less

Curriculum Guide for Electronics in Technology Education.

ERIC Educational Resources Information Center

Connecticut Industrial Technology Association.

Consistent with the principles of the Connecticut Common Core of Learning, this competency-based curriculum guide for electronics provides a reference guide for educators to research and prepare for teaching the field of electronics. The guide contains 22 units that cover the following topics: theory of matter; safety; direct current; magnetism;…

Brushed permanent magnet DC MLC motor operation in an external magnetic field.

PubMed

Yun, J; St Aubin, J; Rathee, S; Fallone, B G

2010-05-01

Linac-MR systems for real-time image-guided radiotherapy will utilize the multileaf collimators (MLCs) to perform conformal radiotherapy and tumor tracking. The MLCs would be exposed to the external fringe magnetic fields of the linac-MR hybrid systems. Therefore, an experimental investigation of the effect of an external magnetic field on the brushed permanent magnet DC motors used in some MLC systems was performed. The changes in motor speed and current were measured for varying external magnetic field strengths up to 2000 G generated by an EEV electromagnet. These changes in motor characteristics were measured for three orientations of the motor in the external magnetic field, mimicking changes in motor orientations due to installation and/or collimator rotations. In addition, the functionality of the associated magnetic motor encoder was tested. The tested motors are used with the Varian 120 leaf Millennium MLC (Maxon Motor half leaf and full leaf motors) and the Varian 52 leaf MKII MLC (MicroMo Electronics leaf motor) including a carriage motor (MicroMo Electronics). In most cases, the magnetic encoder of the motors failed prior to any damage to the gearbox or the permanent magnet motor itself. This sets an upper limit of the external magnetic field strength on the motor function. The measured limits of the external magnetic fields were found to vary by the motor type. The leaf motor used with a Varian 52 leaf MKII MLC system tolerated up to 450 +/- 10 G. The carriage motor tolerated up to 2000 +/- 10 G field. The motors used with the Varian 120 leaf Millennium MLC system were found to tolerate a maximum of 600 +/- 10 G. The current Varian MLC system motors can be used for real-time image-guided radiotherapy coupled to a linac-MR system, provided the fringe magnetic fields at their locations are below the determined tolerance levels. With the fringe magnetic fields of linac-MR systems expected to be larger than the tolerance levels determined, some form of magnetic shielding would be required.

Effect of magnetic helicity upon rectilinear propagation of charged particles in random magnetic fields

NASA Technical Reports Server (NTRS)

Earl, James A.

1992-01-01

When charged particles spiral along a large constant magnetic field, their trajectories are scattered by any random field components that are superposed on the guiding field. If the random field configuration embodies helicity, the scattering is asymmetrical with respect to a plane perpendicular to the guiding field, for particles moving into the forward hemisphere are scattered at different rates from those moving into the backward hemisphere. This asymmetry gives rise to new terms in the transport equations that describe propagation of charged particles. Helicity has virtually no impact on qualitative features of the diffusive mode of propagation. However, characteristic velocities of the coherent modes that appear after a highly anisotropic injection exhibit an asymmetry related to helicity. Explicit formulas, which embody the effects of helicity, are given for the anisotropies, the coefficient diffusion, and the coherent velocities. Predictions derived from these expressions are in good agreement with Monte Carlo simulations of particle transport, but the simulations reveal certain phenomena whose explanation calls for further analytical work.

Method And Apparatus For Launching Microwave Energy Into A Plasma Processing Chamber

DOEpatents

DOUGHTY, FRANK C.; [et al

2001-05-01

A method and apparatus for launching microwave energy to a plasma processing chamber in which the required magnetic field is generated by a permanent magnet structure and the permanent magnet material effectively comprises one or more surfaces of the waveguide structure. The waveguide structure functions as an impedance matching device and controls the field pattern of the launched microwave field to create a uniform plasma. The waveguide launcher may comprise a rectangular waveguide, a circular waveguide, or a coaxial waveguide with permanent magnet material forming the sidewalls of the guide and a magnetization pattern which produces the required microwave electron cyclotron resonance magnetic field, a uniform field absorption pattern, and a rapid decay of the fields away from the resonance zone. In addition, the incorporation of permanent magnet material as a portion of the waveguide structure places the magnetic material in close proximity to the vacuum chamber, allowing for a precisely controlled magnetic field configuration, and a reduction of the amount of permanent magnet material required.

Controlled Waveform Magnets

NASA Astrophysics Data System (ADS)

Campbell, L. J.; Schlllig, J. B.

Issues for the design and operation of high field controlled waveform magnets and their power supplies are discussed. The basic technical elements are reviewed and applied to problems specific to this class of magnets. Examples are given along with a guide to the literature.

Permanent magnet system to guide superparamagnetic particles

NASA Astrophysics Data System (ADS)

Baun, Olga; Blümler, Peter

2017-10-01

A new concept of using permanent magnet systems for guiding superparamagnetic nano-particles on arbitrary trajectories over a large volume is proposed. The basic idea is to use one magnet system which provides a strong, homogeneous, dipolar magnetic field to magnetize and orient the particles, and a second constantly graded, quadrupolar field, superimposed on the first, to generate a force on the oriented particles. In this configuration the motion of the particles is driven predominantly by the component of the gradient field which is parallel to the direction of the homogeneous field. As a result, particles are guided with constant force and in a single direction over the entire volume. The direction is simply adjusted by varying the angle between quadrupole and dipole. Since a single gradient is impossible due to Gauß' law, the other gradient component of the quadrupole determines the angular deviation of the force. However, the latter can be neglected if the homogeneous field is stronger than the local contribution of the quadrupole field. A possible realization of this idea is a coaxial arrangement of two Halbach cylinders. A dipole to evenly magnetize and orient the particles, and a quadrupole to generate the force. The local force was calculated analytically for this particular geometry and the directional limits were analyzed and discussed. A simple prototype was constructed to demonstrate the principle in two dimensions on several nano-particles of different size, which were moved along a rough square by manual adjustment of the force angle. The observed velocities of superparamagnetic particles in this prototype were always several orders of magnitude higher than the theoretically expected value. This discrepancy is attributed to the observed formation of long particle chains as a result of their polarization by the homogeneous field. The magnetic moment of such a chain is then the combination of that of its constituents, while its hydrodynamic radius stays low. A complete system will consist of another quadrupole (third cylinder) to additionally enable scaling of the gradient/force strength by another rotation. In this configuration the device could then also be used as a simple MRI machine to image the particles between movement intervals. Finally, a concept is proposed by which superparamagnetic particles can be guided in three-dimensional space.

Degenerate variational integrators for magnetic field line flow and guiding center trajectories

NASA Astrophysics Data System (ADS)

Ellison, C. L.; Finn, J. M.; Burby, J. W.; Kraus, M.; Qin, H.; Tang, W. M.

2018-05-01

Symplectic integrators offer many benefits for numerically approximating solutions to Hamiltonian differential equations, including bounded energy error and the preservation of invariant sets. Two important Hamiltonian systems encountered in plasma physics—the flow of magnetic field lines and the guiding center motion of magnetized charged particles—resist symplectic integration by conventional means because the dynamics are most naturally formulated in non-canonical coordinates. New algorithms were recently developed using the variational integration formalism; however, those integrators were found to admit parasitic mode instabilities due to their multistep character. This work eliminates the multistep character, and therefore the parasitic mode instabilities via an adaptation of the variational integration formalism that we deem "degenerate variational integration." Both the magnetic field line and guiding center Lagrangians are degenerate in the sense that the resultant Euler-Lagrange equations are systems of first-order ordinary differential equations. We show that retaining the same degree of degeneracy when constructing discrete Lagrangians yields one-step variational integrators preserving a non-canonical symplectic structure. Numerical examples demonstrate the benefits of the new algorithms, including superior stability relative to the existing variational integrators for these systems and superior qualitative behavior relative to non-conservative algorithms.

Wireless power transfer magnetic couplers

DOEpatents

Wu, Hunter; Gilchrist, Aaron; Sealy, Kylee

2016-01-19

A magnetic coupler is disclosed for wireless power transfer systems. A ferrimagnetic component is capable of guiding a magnetic field. A wire coil is wrapped around at least a portion of the ferrimagnetic component. A screen is capable of blocking leakage magnetic fields. The screen may be positioned to cover at least one side of the ferrimagnetic component and the coil. A distance across the screen may be at least six times an air gap distance between the ferrimagnetic component and a receiving magnetic coupler.

Near-infrared-absorbing gold nanopopcorns with iron oxide cluster core for magnetically amplified photothermal and photodynamic cancer therapy.

PubMed

Bhana, Saheel; Lin, Gan; Wang, Lijia; Starring, Hunter; Mishra, Sanjay R; Liu, Gang; Huang, Xiaohua

2015-06-03

We present the synthesis and application of a new type of dual magnetic and plasmonic nanostructures for magnetic-field-guided drug delivery and combined photothermal and photodynamic cancer therapy. Near-infrared-absorbing gold nanopopcorns containing a self-assembled iron oxide cluster core were prepared via a seed-mediated growth method. The hybrid nanostructures are superparamagnetic and show great photothermal conversion efficiency (η=61%) under near-infrared irradiation. Compact and stable nanocomplexes for photothermal-photodynamic therapy were formed by coating the nanoparticles with near-infrared-absorbing photosensitizer silicon 2,3-naphthalocyannie dihydroxide and stabilization with poly(ethylene glycol) linked with 11-mercaptoundecanoic acid. The nanocomplex showed enhanced release and cellular uptake of the photosensitizer with the use of a gradient magnetic field. In vitro studies using two different cell lines showed that the dual mode photothermal and photodynamic therapy with the assistance of magnetic-field-guided drug delivery dramatically improved the therapeutic efficacy of cancer cells as compared to the combination treatment without using a magnetic field and the two treatments alone. The "three-in-one" nanocomplex has the potential to carry therapeutic agents deep into a tumor through magnetic manipulation and to completely eradicate tumors by subsequent photothermal and photodynamic therapies without systemic toxicity.

Stability analysis of a deterministic dose calculation for MRI-guided radiotherapy.

PubMed

Zelyak, O; Fallone, B G; St-Aubin, J

2017-12-14

Modern effort in radiotherapy to address the challenges of tumor localization and motion has led to the development of MRI guided radiotherapy technologies. Accurate dose calculations must properly account for the effects of the MRI magnetic fields. Previous work has investigated the accuracy of a deterministic linear Boltzmann transport equation (LBTE) solver that includes magnetic field, but not the stability of the iterative solution method. In this work, we perform a stability analysis of this deterministic algorithm including an investigation of the convergence rate dependencies on the magnetic field, material density, energy, and anisotropy expansion. The iterative convergence rate of the continuous and discretized LBTE including magnetic fields is determined by analyzing the spectral radius using Fourier analysis for the stationary source iteration (SI) scheme. The spectral radius is calculated when the magnetic field is included (1) as a part of the iteration source, and (2) inside the streaming-collision operator. The non-stationary Krylov subspace solver GMRES is also investigated as a potential method to accelerate the iterative convergence, and an angular parallel computing methodology is investigated as a method to enhance the efficiency of the calculation. SI is found to be unstable when the magnetic field is part of the iteration source, but unconditionally stable when the magnetic field is included in the streaming-collision operator. The discretized LBTE with magnetic fields using a space-angle upwind stabilized discontinuous finite element method (DFEM) was also found to be unconditionally stable, but the spectral radius rapidly reaches unity for very low-density media and increasing magnetic field strengths indicating arbitrarily slow convergence rates. However, GMRES is shown to significantly accelerate the DFEM convergence rate showing only a weak dependence on the magnetic field. In addition, the use of an angular parallel computing strategy is shown to potentially increase the efficiency of the dose calculation.

Stability analysis of a deterministic dose calculation for MRI-guided radiotherapy

NASA Astrophysics Data System (ADS)

Zelyak, O.; Fallone, B. G.; St-Aubin, J.

2018-01-01

Modern effort in radiotherapy to address the challenges of tumor localization and motion has led to the development of MRI guided radiotherapy technologies. Accurate dose calculations must properly account for the effects of the MRI magnetic fields. Previous work has investigated the accuracy of a deterministic linear Boltzmann transport equation (LBTE) solver that includes magnetic field, but not the stability of the iterative solution method. In this work, we perform a stability analysis of this deterministic algorithm including an investigation of the convergence rate dependencies on the magnetic field, material density, energy, and anisotropy expansion. The iterative convergence rate of the continuous and discretized LBTE including magnetic fields is determined by analyzing the spectral radius using Fourier analysis for the stationary source iteration (SI) scheme. The spectral radius is calculated when the magnetic field is included (1) as a part of the iteration source, and (2) inside the streaming-collision operator. The non-stationary Krylov subspace solver GMRES is also investigated as a potential method to accelerate the iterative convergence, and an angular parallel computing methodology is investigated as a method to enhance the efficiency of the calculation. SI is found to be unstable when the magnetic field is part of the iteration source, but unconditionally stable when the magnetic field is included in the streaming-collision operator. The discretized LBTE with magnetic fields using a space-angle upwind stabilized discontinuous finite element method (DFEM) was also found to be unconditionally stable, but the spectral radius rapidly reaches unity for very low-density media and increasing magnetic field strengths indicating arbitrarily slow convergence rates. However, GMRES is shown to significantly accelerate the DFEM convergence rate showing only a weak dependence on the magnetic field. In addition, the use of an angular parallel computing strategy is shown to potentially increase the efficiency of the dose calculation.

Corrigendum to "Stability analysis of a deterministic dose calculation for MRI-guided radiotherapy".

PubMed

Zelyak, Oleksandr; Fallone, B Gino; St-Aubin, Joel

2018-03-12

Modern effort in radiotherapy to address the challenges of tumor localization and motion has led to the development of MRI guided radiotherapy technologies. Accurate dose calculations must properly account for the effects of the MRI magnetic fields. Previous work has investigated the accuracy of a deterministic linear Boltzmann transport equation (LBTE) solver that includes magnetic field, but not the stability of the iterative solution method. In this work, we perform a stability analysis of this deterministic algorithm including an investigation of the convergence rate dependencies on the magnetic field, material density, energy, and anisotropy expansion. The iterative convergence rate of the continuous and discretized LBTE including magnetic fields is determined by analyzing the spectral radius using Fourier analysis for the stationary source iteration (SI) scheme. The spectral radius is calculated when the magnetic field is included (1) as a part of the iteration source, and (2) inside the streaming-collision operator. The non-stationary Krylov subspace solver GMRES is also investigated as a potential method to accelerate the iterative convergence, and an angular parallel computing methodology is investigated as a method to enhance the efficiency of the calculation. SI is found to be unstable when the magnetic field is part of the iteration source, but unconditionally stable when the magnetic field is included in the streaming-collision operator. The discretized LBTE with magnetic fields using a space-angle upwind stabilized discontinuous finite element method (DFEM) was also found to be unconditionally stable, but the spectral radius rapidly reaches unity for very low density media and increasing magnetic field strengths indicating arbitrarily slow convergence rates. However, GMRES is shown to significantly accelerate the DFEM convergence rate showing only a weak dependence on the magnetic field. In addition, the use of an angular parallel computing strategy is shown to potentially increase the efficiency of the dose calculation. © 2018 Institute of Physics and Engineering in Medicine.

A dynamic magnetic tension force as the cause of failed solar eruptions

DOE Data Explorer

Myers, Clayton E. [Princeton Univ., NJ (United States). Dept. of Astrophysical Sciences; Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); ] (ORCID:0000000345398406); Yamada, Maasaki [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States)] (ORCID:0000000349961649); Ji, Hantao [Princeton Univ., NJ (United States). Dept. of Astrophysical Sciences; Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Laboratory for Space Environment and Physical Sciences, Harbin Institute of Technology, Harbin, Heilongjiang 150001, China] (ORCID:0000000196009963); Yoo, Jongsoo [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States)] (ORCID:0000000338811995); Fox, William [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States)] (ORCID:000000016289858X); Jara-Almonte, Jonathan [Princeton Univ., NJ (United States). Dept. of Astrophysical Sciences; Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); ] (ORCID:0000000307606198); Savcheva, Antonia [Harvard†“ Smithsonian Center for Astrophysics, Cambridge, Massachusetts 02138, USA] (ORCID:000000025598046X); DeLuca, Edward E. [Harvard†“ Smithsonian Center for Astrophysics, Cambridge, Massachusetts 02138, USA] (ORCID:0000000174162895)

2015-12-11

Coronal mass ejections are solar eruptions driven by a sudden release of magnetic energy stored in the Sun’s corona. In many cases, this magnetic energy is stored in long-lived, arched structures called magnetic flux ropes. When a flux rope destabilizes, it can either erupt and produce a coronal mass ejection or fail and collapse back towards the Sun. The prevailing belief is that the outcome of a given event is determined by a magnetohydrodynamic force imbalance called the torus instability. This belief is challenged, however, by observations indicating that torus-unstable flux ropes sometimes fail to erupt. This contradiction has not yet been resolved because of a lack of coronal magnetic field measurements and the limitations of idealized numerical modelling. Here we report the results of a laboratory experiment that reveal a previously unknown eruption criterion below which torus-unstable flux ropes fail to erupt. We find that such ‘failed torus’ events occur when the guide magnetic field (that is, the ambient field that runs toroidally along the flux rope) is strong enough to prevent the flux rope from kinking. Under these conditions, the guide field interacts with electric currents in the flux rope to produce a dynamic toroidal field tension force that halts the eruption. This magnetic tension force is missing from existing eruption models, which is why such models cannot explain or predict failed torus events.

Safety of High Speed Guided Ground Transportation Systems - The Biological Effects of Maglev Magnetic Field Exposures

DOT National Transportation Integrated Search

1993-08-01

This report describes selected biological effects on transformed human cell lines and on rats from exposure to simulated : maglev magnetic fields (MFs). Rats (n = 6 per group) were exposed at various times throughout the 24-h day to MFs : simulating ...

Diffusion of external magnetic fields into the cone-in-shell target in the fast ignition

NASA Astrophysics Data System (ADS)

Sunahara, Atsushi; Morita, Hiroki; Johzaki, Tomoyuki; Nagatomo, Hideo; Fujioka, Shinsuke; Hassanein, Ahmed; Firex Project Team

2017-10-01

We simulated the diffusion of externally applied magnetic fields into cone-in-shell target in the fast ignition. Recently, in the fast ignition scheme, the externally magnetic fields up to kilo-Tesla is used to guide fast electrons to the high-dense imploded core. In order to study the profile of the magnetic field, we have developed 2D cylindrical Maxwell equation solver with Ohm's law, and carried out simulations of diffusion of externally applied magnetic fields into a cone-in-shell target. We estimated the conductivity of the cone and shell target based on the assumption of Saha-ionization equilibrium. Also, we calculated the temporal evolution of the target temperature heated by the eddy current driven by temporal variation of magnetic fields, based on the accurate equation of state. Both, the diffusion of magnetic field and the increase of target temperature interact with each other. We present our results of temporal evolution of the magnetic field and its diffusion into the cone and shell target.

MMS Observations of Large Guide Field Symmetric Reconnection Between Colliding Reconnection Jets at the Center of a Magnetic Flux Rope at the Magnetopause

NASA Technical Reports Server (NTRS)

Oieroset, M.; Phan, T. D.; Haggerty, C.; Shay, M. A.; Eastwood, J. P.; Gershman, D. J.; Drake, J. F.; Fujimoto, M.; Ergun, R. E.; Mozer, F. S.;

MMS observations of large guide field symmetric reconnection between colliding reconnection jets at the center of a magnetic flux rope at the magnetopause

NASA Astrophysics Data System (ADS)

Øieroset, M.; Phan, T. D.; Haggerty, C.; Shay, M. A.; Eastwood, J. P.; Gershman, D. J.; Drake, J. F.; Fujimoto, M.; Ergun, R. E.; Mozer, F. S.; Oka, M.; Torbert, R. B.; Burch, J. L.; Wang, S.; Chen, L. J.; Swisdak, M.; Pollock, C.; Dorelli, J. C.; Fuselier, S. A.; Lavraud, B.; Giles, B. L.; Moore, T. E.; Saito, Y.; Avanov, L. A.; Paterson, W.; Strangeway, R. J.; Russell, C. T.; Khotyaintsev, Y.; Lindqvist, P. A.; Malakit, K.

2016-06-01

We report evidence for reconnection between colliding reconnection jets in a compressed current sheet at the center of a magnetic flux rope at Earth's magnetopause. The reconnection involved nearly symmetric inflow boundary conditions with a strong guide field of two. The thin (2.5 ion-skin depth (di) width) current sheet (at ~12 di downstream of the X line) was well resolved by MMS, which revealed large asymmetries in plasma and field structures in the exhaust. Ion perpendicular heating, electron parallel heating, and density compression occurred on one side of the exhaust, while ion parallel heating and density depression were shifted to the other side. The normal electric field and double out-of-plane (bifurcated) currents spanned almost the entire exhaust. These observations are in good agreement with a kinetic simulation for similar boundary conditions, demonstrating in new detail that the structure of large guide field symmetric reconnection is distinctly different from antiparallel reconnection.

MMS observations of large guide field symmetric reconnection between colliding reconnection jets at the center of a magnetic flux rope at the magnetopause

NASA Astrophysics Data System (ADS)

Oieroset, M.; Phan, T.; Haggerty, C. C.; Shay, M. A.; Eastwood, J. P.; Gershman, D. J.; Drake, J. F.; Fujimoto, M.; Ergun, R.; Mozer, F.; Oka, M.; Torbert, R. B.; Burch, J. L.; Wang, S.; Chen, L. J.; Swisdak, M.; Pollock, C.; Dorelli, J.; Fuselier, S. A.; Lavraud, B.; Giles, B. L.; Moore, T. E.; Saito, Y.; Avanov, L. A.; Paterson, W. R.; Strangeway, R. J.; Russell, C. T.; Khotyaintsev, Y. V.; Lindqvist, P. A.; Malakit, K.

2016-12-01

We report evidence for reconnection between colliding reconnection jets in a compressed current sheet at the center of a magnetic flux rope at Earth's magnetopause. The reconnection involved nearly symmetric inflow boundary conditions with a strong guide field of two. The thin (2.5 ion-skin depth (di) width) current sheet (at 12 di downstream of the X line) was well resolved by Magnetospheric Multiscale, which revealed large asymmetries in plasma and field structures in the exhaust. Ion perpendicular heating, electron parallel heating, and density compression occurred on one side of the exhaust, while ion parallel heating and density depression were shifted to the other side. The normal electric field and double out-of-plane (bifurcated) currents spanned almost the entire exhaust. These observations are in good agreement with a kinetic simulation for similar boundary conditions, demonstrating in new detail that the structure of large guide field symmetric reconnection is distinctly different from antiparallel reconnection.

Magnetic particles guided by ellipsoidal AC magnetic fields in a shallow viscous fluid: Controlling trajectories and chain lengths

NASA Astrophysics Data System (ADS)

Jorge, Guillermo A.; Llera, María; Bekeris, Victoria

2017-12-01

We study the propulsion of superparamagnetic particles dispersed in a viscous fluid upon the application of an elliptically polarized rotating magnetic field. Reducing the fluid surface tension the particles sediment due to density mismatch and rotate close to the low recipient confining plate. We study the net translational motion arising from the hydrodynamic coupling with the plate and find that, above a cross over magnetic field, magnetically assembled doublets move faster than single particles. In turn, particles are driven in complex highly controlled trajectories by rotating the plane containing the magnetic field vector. The effect of the field rotation on long self assembled chains is discussed and the alternating breakup and reformation of the particle chains is described.

A Magnetic-Field Guided Interface Coassembly Approach to Magnetic Mesoporous Silica Nanochains for Osteoclast-Targeted Inhibition and Heterogeneous Nanocatalysis.

PubMed

Wan, Li; Song, Hongyuan; Chen, Xiao; Zhang, Yu; Yue, Qin; Pan, Panpan; Su, Jiacan; Elzatahry, Ahmed A; Deng, Yonghui

2018-06-01

1D core-shell magnetic materials with mesopores in shell are highly desired for biocatalysis, magnetic bioseparation, and bioenrichment and biosensing because of their unique microstructure and morphology. In this study, 1D magnetic mesoporous silica nanochains (Fe 3 O 4 @nSiO 2 @mSiO 2 nanochain, Magn-MSNCs named as FDUcs-17C) are facilely synthesized via a novel magnetic-field-guided interface coassembly approach in two steps. Fe 3 O 4 particles are coated with nonporous silica in a magnetic field to form 1D Fe 3 O 4 @nSiO 2 nanochains. A further interface coassembly of cetyltrimethylammonium bromide and silica source in water/n-hexane biliquid system leads to 1D Magn-MSNCs with core-shell-shell structure, uniform diameter (≈310 nm), large and perpendicular mesopores (7.3 nm), high surface area (317 m 2 g -1 ), and high magnetization (34.9 emu g -1 ). Under a rotating magnetic field, the nanochains with loaded zoledronate (a medication for treating bone diseases) in the mesopores, show an interesting suppression effect of osteoclasts differentiation, due to their 1D nanostructure that provides a shearing force in dynamic magnetic field to induce sufficient and effective reactions in cells. Moreover, by loading Au nanoparticles in the mesopores, the 1D Fe 3 O 4 @nSiO 2 @mSiO 2 -Au nanochains can service as a catalytically active magnetic nanostirrer for hydrogenation of 4-nitrophenol with high catalytic performance and good magnetic recyclability. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

The status of Fast Ignition Realization Experiment (FIREX) and prospects for inertial fusion energy

NASA Astrophysics Data System (ADS)

Azechi, H.; FIREX Project Team

2016-05-01

Here we report recent progress for the fast ignition inertial confinement fusion demonstration. The fraction of low energy (< 1 MeV) component of the relativistic electron beam (REB), which efficiently heats the fuel core, increases by a factor of 4 by enhancing pulse contrast of heating laser and removing preformed plasma sources. Kilo-tesla magnetic field is studied to guide the diverging REB to the fuel core. The transport simulation of the REB accelerated by the heating laser in the externally applied and compressed magnetic field indicates that the REB can be guided efficiently to the fuel core. The integrated simulation shows > 4% of the heating efficiency and > 4 keV of ion temperature are achievable by using GEKKO-XII and LFEX, properly designed cone-fuel and an external magnetic field.

Magnetic Recording.

ERIC Educational Resources Information Center

Lowman, Charles E.

A guide to the technology of magnetic recorders used in such fields as audio recording, broadcast and closed-circuit television, instrumentation recording, and computer data systems is presented. Included are discussions of applications, advantages, and limitations of magnetic recording, its basic principles and theory of operation, and its…

Scaling of Asymmetric Magnetic Reconnection Rate with Guide Field

NASA Astrophysics Data System (ADS)

Liang, H.; Cassak, P.; Swisdak, M.; Hartke, T.; Oieroset, M.; Phan, T.; Liu, Y. H.; Hesse, M.; Shay, M.; Beidler, M.

2017-12-01

An out-of-plane (guide) magnetic field in asymmetric magnetic reconnection with an in-plane gas pressure gradient can lead to diamagnetic effects in the plane of reconnection. Simulations showed that such effects can make the X-line convect in the outflow direction and reduce the reconnection rate. They can even suppress the reconnection completely under certain upstream conditions. The complete suppression of reconnection due to these effects has been observed in the solar wind and Earth's magnetopause, and it has also been discussed as being important in the outer heliosphere, the magnetospheres of Jupiter, Saturn, and Mercury, and in magnetically confined fusion devices. Recent studies showed that diamagnetic effects set up by a density gradient are different from those set up by a temperature gradient. Although it is known that reconnection can be significantly slowed down and even suppressed by diamagnetic effects, there is neither a comprehensive understanding of the impact of the guide field and the diamagnetic effects on asymmetric reconnection nor quantitative scaling prediction for the reconnection rate as a function of arbitrary upstream conditions including guide fields. The purpose of this work is a first step towards these goals. We investigate the scaling of the reconnection rate using two-dimensional particle-in-cell simulations. This study will be important for asymmetric reconnections in many settings, including those in the solar wind and those at planetary magnetospheres in reference to solar wind-magnetospheric coupling at the dayside magnetopause. It will also be useful for gaining perspective and making comparisons to Magnetospheric Multiscale (MMS) observations of dayside reconnection.

Life on magnets: stem cell networking on micro-magnet arrays.

PubMed

Zablotskii, Vitalii; Dejneka, Alexandr; Kubinová, Šárka; Le-Roy, Damien; Dumas-Bouchiat, Frédéric; Givord, Dominique; Dempsey, Nora M; Syková, Eva

2013-01-01

Interactions between a micro-magnet array and living cells may guide the establishment of cell networks due to the cellular response to a magnetic field. To manipulate mesenchymal stem cells free of magnetic nanoparticles by a high magnetic field gradient, we used high quality micro-patterned NdFeB films around which the stray field's value and direction drastically change across the cell body. Such micro-magnet arrays coated with parylene produce high magnetic field gradients that affect the cells in two main ways: i) causing cell migration and adherence to a covered magnetic surface and ii) elongating the cells in the directions parallel to the edges of the micro-magnet. To explain these effects, three putative mechanisms that incorporate both physical and biological factors influencing the cells are suggested. It is shown that the static high magnetic field gradient generated by the micro-magnet arrays are capable of assisting cell migration to those areas with the strongest magnetic field gradient, thereby allowing the build up of tunable interconnected stem cell networks, which is an elegant route for tissue engineering and regenerative medicine.

Magnetically guiding and orienting integrated chemical sensors

NASA Astrophysics Data System (ADS)

Anker, Jeffrey N.; Lee, Yong-Eun Koo; Kopelman, Raoul

2014-08-01

Fluorescent microsensors for detecting pH and oxygen were positioned and oriented using magnetic tweezers. These multifunctional integrated microsensors were fabricated by physically linking together nano-components including magnetic nanoparticles, fluorescent nanoparticles, and metal hemisphere-shells. Two such microsensors are magnetic roll-shaped polystyrene particles with 120 nm fluorescent oxygen-sensing ormosil nanospheres that are physically pressed ("breaded") into the roll surface, and 4-5 µm fluorescent microspheres that are capped with a 50 nm thick metal hemispherical shell. The magnetic tweezers consisted of an iron wire that was magnetized in an external magnetic field. Rotating this external field oriented and rotated the microsensors.

Lagrangian and Hamiltonian constraints for guiding-center Hamiltonian theories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tronko, Natalia; Brizard, Alain J.

A consistent guiding-center Hamiltonian theory is derived by Lie-transform perturbation method, with terms up to second order in magnetic-field nonuniformity. Consistency is demonstrated by showing that the guiding-center transformation presented here satisfies separate Jacobian and Lagrangian constraints that have not been explored before. A new first-order term appearing in the guiding-center phase-space Lagrangian is identified through a calculation of the guiding-center polarization. It is shown that this new polarization term also yields a simpler expression of the guiding-center toroidal canonical momentum, which satisfies an exact conservation law in axisymmetric magnetic geometries. Finally, an application of the guiding-center Lagrangian constraint onmore » the guiding-center Hamiltonian yields a natural interpretation for its higher-order corrections.« less

Directed transport of active magnetotactic bacteria in porous media flow

NASA Astrophysics Data System (ADS)

Waisbord, Nicolas; Dehkharghani, Amin; Coons, Thomas; Guasto, Jeffrey S.

2017-11-01

Swimming cell migration through porous media is a topic of ecological and technical relevance for understanding sediment ecosystems and bioremediation of soil for decontamination. We focus on magnetotactic bacteria - which align passively with Earth's magnetic field and migrate in such sediment environments - as a model system. The transport properties of magnetotactic bacteria are measured in a 2D microfluidic porous medium as a function of the porous microstructure geometry and under a variety of environmental conditions. In a quiescent fluid and in the absence of an external, guiding magnetic field, the effective diffusion of cells' random walk is unsurprisingly hindered with decreasing porosity due to cell-surface interactions. When guided by a magnetic field, cell trajectories acquire a net direction and form lanes, a behavior that is enhanced with increasing magnetic field. When the directed motility is coupled with an opposing fluid flow through the porous medium, convective cells form and locally trap the swimming bacteria. These results, which are corroborated by Langevin Simulations are an important step toward understanding magnetotactic bacterial ecology as well as for the magnetic guidance of microrobots in complex environments. Supported by NSF Grant CBET-1511340.

Measurement of magnetic field fluctuations and diamagnetic currents within a laser ablation plasma interacting with an axial magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ikeda, S.; Horioka, K.; Okamura, M.

Here, the guiding of laser ablation plasmas with axial magnetic fields has been used for many applications, since its effectiveness has been proven empirically. For more sophisticated and complicated manipulations of the plasma flow, the behavior of the magnetic field during the interaction and the induced diamagnetic current in the plasma plume needs to be clearly understood. To achieve the first milestone for establishing magnetic plasma manipulation, we measured the spatial and temporal fluctuations of the magnetic field caused by the diamagnetic current. We showed that the small fluctuations of the magnetic field can be detected by using a simplemore » magnetic probe. We observed that the field penetrates to the core of the plasma plume. The diamagnetic current estimated from the magnetic field had temporal and spatial distributions which were confirmed to be correlated with the transformation of the plasma plume. Our results show that the measurement by the magnetic probe is an effective method to observe the temporal and spatial distributions of the magnetic field and diamagnetic current. The systematic measurement of the magnetic field variations is a valuable method to establish the magnetic field manipulation of the laser ablation plasma.« less

Measurement of magnetic field fluctuations and diamagnetic currents within a laser ablation plasma interacting with an axial magnetic field

DOE PAGES

Ikeda, S.; Horioka, K.; Okamura, M.

2017-10-10

Here, the guiding of laser ablation plasmas with axial magnetic fields has been used for many applications, since its effectiveness has been proven empirically. For more sophisticated and complicated manipulations of the plasma flow, the behavior of the magnetic field during the interaction and the induced diamagnetic current in the plasma plume needs to be clearly understood. To achieve the first milestone for establishing magnetic plasma manipulation, we measured the spatial and temporal fluctuations of the magnetic field caused by the diamagnetic current. We showed that the small fluctuations of the magnetic field can be detected by using a simplemore » magnetic probe. We observed that the field penetrates to the core of the plasma plume. The diamagnetic current estimated from the magnetic field had temporal and spatial distributions which were confirmed to be correlated with the transformation of the plasma plume. Our results show that the measurement by the magnetic probe is an effective method to observe the temporal and spatial distributions of the magnetic field and diamagnetic current. The systematic measurement of the magnetic field variations is a valuable method to establish the magnetic field manipulation of the laser ablation plasma.« less

Improved foilless Ku-band transit-time oscillator for generating gigawatt level microwave with low guiding magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ling, Junpu; He, Juntao, E-mail: hejuntao12@163.com; Zhang, Jiande

2014-09-15

An improved foilless Ku-band transit-time oscillator with low guiding magnetic field is proposed and investigated in this paper. With a non-uniform buncher and a coaxial TM{sub 02} mode dual-resonant reflector, this improved device can output gigawatt level Ku-band microwave with relatively compact radial dimensions. Besides the above virtue, this novel reflector also has the merits of high TEM reflectance, being more suitable for pre-modulating the electron beam and enhancing the conversion efficiency. Moreover, in order to further increase the conversion efficiency and lower the power saturation time, a depth-tunable coaxial collector and a resonant cavity located before the extractor aremore » employed in our device. Main structure parameters of the device are optimized by particle in cell simulations. The typical simulation result is that, with a 380 kV, 8.2 kA beam guided by a magnetic field of about 0.6 T, 1.15 GW microwave pulse at 14.25 GHz is generated, yielding a conversion efficiency of about 37%.« less

Superconducting 3D Transmon Qubits for Analog Quantum Simulations

NASA Astrophysics Data System (ADS)

Gargiulo, Oscar; Oleschko, Stefan; Muppalla, Phani; Dalmonte, Marcello; Zoller, Peter; Kirchmair, Gerhard

We present an experimental investigation of the tunability of a 3D transmon qubit through the use of multiple magnetic fields. The 3D transmon is placed inside a copper cavity with sockets for coils and a hole for a magnetic hose. The magnetic hose is used to guide the magnetic field inside the cavity minimizing Eddy currents in the copper wall. As a first step we analyse the qubit tuning with static magnetic fields applied through the use of external coils. This allows us to set the qubit frequency to the desired bias point. Then we show that we can switch the magnetic field inside the cavity on fast time scales through the use of the magnetic hose. We also investigate the influence of the magnetic hose on the coherence time of the qubit.

Variables that influence energy partition in asymmetric reconnection

NASA Astrophysics Data System (ADS)

Wang, S.; Chen, L. J.; Bessho, N.; Hesse, M.; Yamada, M.; Yoo, J.

2017-12-01

The energy conversion in the diffusion region during asymmetric reconnection is studied using particle-in-cell (PIC) simulations and measurements from the Magnetospheric Multiscale (MMS) spacecraft. The simulation analysis shows that the energy partition is highly region-dependent and varies with the guide field strength. Without a guide field, within the central electron diffusion region, the input magnetic energy is mostly converted to the electron thermal energies; half of the magnetic energy input to the region extending from the X-line to a few ion inertial lengths downstream where the ion outflow peaks is converted to the plasma energy gain, with approximately equal partition between ions and electrons, similar to the laboratory results from the Magnetic Reconnection Experiment (MRX); over the entire ion diffusion region, about half of the energy goes to ions, and 20% goes to electrons. Electrons obtain energies mainly from the reconnection electric field (Er). For the ion total energy gain in the diffusion region, about 2/3 comes from the in-plane electrostatic field Ein and 1/3 comes from Er. Adding a guide field tends to reduce the plasma energy gain through reducing the contribution from Ein, even though the reconnection rates are similar. The energy partition in the diffusion region observed by MMS is estimated and compared with the results from PIC simulations and MRX experiments.

Safety of High Speed Guided Ground Transportation Systems: Magnetic and Electric Field Testing of the Washington Metropolitan Area Transit Authority (WMATA) System. v. 2. appendices.

DOT National Transportation Integrated Search

1993-06-01

The 51 appendices contain a detailed reporting of the magnetic field characteristics measured onboard the WMATA Metrorail and near associated facilities. The data have been consolidated and presented as efficiently as possible without resorting to su...

Catastrophic onset of fast magnetic reconnection with a guide field

NASA Astrophysics Data System (ADS)

Cassak, P. A.; Drake, J. F.; Shay, M. A.

2007-05-01

It was recently shown that the slow (collisional) Sweet-Parker and the fast (collisionless) Hall magnetic reconnection solutions simultaneously exist for a wide range of resistivities; reconnection is bistable [Cassak, Shay, and Drake, Phys. Rev. Lett., 95, 235002 (2005)]. When the thickness of the dissipation region becomes smaller than a critical value, the Sweet-Parker solution disappears and fast reconnection ensues, potentially explaining how large amounts of magnetic free energy can accrue without significant release before the onset of fast reconnection. Two-fluid numerical simulations extending the previous results for anti-parallel reconnection (where the critical thickness is the ion skin depth) to component reconnection with a large guide field (where the critical thickness is the thermal ion Larmor radius) are presented. Applications to laboratory experiments of magnetic reconnection and the sawtooth crash are discussed.

Scaled-down particle-in-cell simulation of cathode plasma expansion in magnetically insulated coaxial diode

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhu, Danni; Zhang, Jun, E-mail: zhangjun@nudt.edu.cn; Zhong, Huihuang

2016-03-15

The expansion of cathode plasma in magnetically insulated coaxial diode (MICD) is investigated in theory and particle-in-cell (PIC) simulation. The temperature and density of the cathode plasma are about several eV and 10{sup 13}–10{sup 16 }cm{sup −3}, respectively, and its expansion velocity is of the level of few cm/μs. Through hydrodynamic theory analysis, expressions of expansion velocities in axial and radial directions are obtained. The characteristics of cathode plasma expansion have been simulated through scaled-down PIC models. Simulation results indicate that the expansion velocity is dominated by the ratio of plasma density other than the static electric field. The electric fieldmore » counteracts the plasma expansion reverse of it. The axial guiding magnetic field only reduces the radial transport coefficients by a correction factor, but not the axial ones. Both the outward and inward radial expansions of a MICD are suppressed by the much stronger guiding magnetic field and even cease.« less

Investigations of plasmoid reconnection in the presence of strong guide fields in CHI plasma start-up on HIST

NASA Astrophysics Data System (ADS)

Nagata, Masayoshi; Fujita, Akihiro; Ibragi, Youhei; Matsui, Takahiro; Kikuchi, Yusuke; Fukumoto, Naoyuki; Kanki, Takashi

2017-10-01

Plasmoid magnetic reconnections have been examined in the Coaxial Helicity Injection (CHI) experiments on HIST. Magnetic reconnections are required for the formation of closed flux surfaces in the transient-CHI start-up plasmas. So far, we have observed formation of plasmoids inside an elongated current layer to create the multiple X-points during the CHI process. According to the MHD simulation by F. Ebrahimi and R. Raman, the reconnection rate based on the plasmoid instability is faster than that by Sweet-Parker (S-P) model. To estimate the Lundquist number S number, we have measured spatial profiles of magnetic field strength, electron density and temperature in the current layer. In this meeting, we will present the effect of the guide (toroidal) magnetic field and mass (H, D and He) on the current layer thickness and reconnection rates of plasmoids. It is found that behavior of plasmoids is synchronized with Ion Doppler temperature, leading to ion heating.

Novel views of the lithospheric magnetic field for hazard mitigation, tectonics, and geology

NASA Astrophysics Data System (ADS)

Purucker, M. E.; Blakely, R. J.; Nelson, J. B.; Bracken, R.; White, T.

2016-12-01

The altitude of magnetic field observations is critical for high-resolution mapping. We advocate two views of the lithospheric magnetic field, at altitudes of 20 and 90 km. Magnetic surveys are most sensitive to sources with wavelengths comparable to the altitude of the survey. Thus, low-altitude satellite surveys emphasize wavelengths greater than 300 km, such as subduction zones and the continent-ocean contrast. Magnetic sources elongated along satellite tracks are subdued, however, and lithospheric features are obscured in the auroral ovals around the magnetic poles. Near-surface surveys (0.1 to 5 km altitudes) are sensitive to tectonic and upper-crustal geologic sources. There are many under-explored regions, even in this near-surface realm, notably the Antarctic and the southern oceans. Few magnetic surveys are available between airborne ( 5 km) and orbital altitudes ( 300 km), and this lack of information reduces knowledge of geologic and tectonic features in this spectral band; e.g., sources associated with the lower crust or that encompass the whole crust are strongly suppressed because the average thickness of continental crust is 30 km. Technologies are being developed to acquire magnetic field information at suborbital altitudes with UAVs at altitudes of 20 km, and with a laser guide star technique for remote sensing at an altitude averaging 90 km. Use of the laser guide star technique on a polar-orbiting satellite with in-situ magnetometers would greatly facilitate separating ionospheric from lithospheric fields. Laser guide stars can be produced in Na-rich layers where micro-meteorite breakup occurs in a planetary or satellite system, and they are ubiquitous in the Solar System. The ideal observation platform at 20 km has small and well-characterized EM fields, can execute maneuvers that permit flying of tie lines, and can fly for long periods so as to survey large areas. A main limitation of surveying remote areas concerns the need for a local base station for resolving temporal-spatial aliasing. The traditional approach of siting temporary base stations in the survey area is often not feasible, and we discuss possible alternatives.

Magnetic microscopic imaging with an optically pumped magnetometer and flux guides

DOE PAGES

Kim, Young Jin; Savukov, Igor Mykhaylovich; Huang, Jen -Huang; ...

2017-01-23

Here, by combining an optically pumped magnetometer (OPM) with flux guides (FGs) and by installing a sample platform on automated translation stages, we have implemented an ultra-sensitive FG-OPM scanning magnetic imaging system that is capable of detecting magnetic fields of ~20 pT with spatial resolution better than 300 μm (expected to reach ~10 pT sensitivity and ~100 μm spatial resolution with optimized FGs). As a demonstration of one possible application of the FG-OPM device, we conducted magnetic imaging of micron-size magnetic particles. Magnetic imaging of such particles, including nano-particles and clusters, is very important for many fields, especially for medicalmore » cancer diagnostics and biophysics applications. For rapid, precise magnetic imaging, we constructed an automatic scanning system, which holds and moves a target sample containing magnetic particles at a given stand-off distance from the FG tips. We show that the device was able to produce clear microscopic magnetic images of 10 μm-size magnetic particles. In addition, we also numerically investigated how the magnetic flux from a target sample at a given stand-off distance is transmitted to the OPM vapor cell.« less

Behavior of moving plasma in solenoidal magnetic field in a laser ion source

NASA Astrophysics Data System (ADS)

Ikeda, S.; Takahashi, K.; Okamura, M.; Horioka, K.

2016-02-01

In a laser ion source, a solenoidal magnetic field is useful to guide the plasma and to control the extracted beam current. However, the behavior of the plasma drifting in the magnetic field has not been well understood. Therefore, to investigate the behavior, we measured the plasma ion current and the total charge within a single pulse in the solenoid by changing the distance from the entrance of the solenoid to a detector. We observed that the decrease of the total charge along the distance became smaller as the magnetic field became larger and then the charge became almost constant with a certain magnetic flux density. The results indicate that the transverse spreading speed of the plasma decreased with increasing the field and the plasma was confined transversely with the magnetic flux density. We found that the reason of the confinement was not magnetization of ions but an influence induced by electrons.

Behavior of moving plasma in solenoidal magnetic field in a laser ion source.

PubMed

Ikeda, S; Takahashi, K; Okamura, M; Horioka, K

2016-02-01

In a laser ion source, a solenoidal magnetic field is useful to guide the plasma and to control the extracted beam current. However, the behavior of the plasma drifting in the magnetic field has not been well understood. Therefore, to investigate the behavior, we measured the plasma ion current and the total charge within a single pulse in the solenoid by changing the distance from the entrance of the solenoid to a detector. We observed that the decrease of the total charge along the distance became smaller as the magnetic field became larger and then the charge became almost constant with a certain magnetic flux density. The results indicate that the transverse spreading speed of the plasma decreased with increasing the field and the plasma was confined transversely with the magnetic flux density. We found that the reason of the confinement was not magnetization of ions but an influence induced by electrons.

A dynamic magnetic tension force as the cause of failed solar eruptions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Myers, Clayton E.; Yamada, Masaaki; Ji, Hantao

Coronal mass ejections are solar eruptions driven by a sudden release of magnetic energy stored in the Sun's corona. In many cases, this magnetic energy is stored in long-lived, arched structures called magnetic flux ropes. When a flux rope destabilizes, it can either erupt and produce a coronal mass ejection or fail and collapse back towards the Sun. The prevailing belief is that the outcome of a given event is determined by a magnetohydrodynamic force imbalance called the torus instability. This belief is challenged, however, by observations indicating that torus-unstable flux ropes sometimes fail to erupt. This contradiction has notmore » yet been resolved because of a lack of coronal magnetic field measurements and the limitations of idealized numerical modelling. In this paper, we report the results of a laboratory experiment that reveal a previously unknown eruption criterion below which torus-unstable flux ropes fail to erupt. We find that such 'failed torus' events occur when the guide magnetic field (that is, the ambient field that runs toroidally along the flux rope) is strong enough to prevent the flux rope from kinking. Under these conditions, the guide field interacts with electric currents in the flux rope to produce a dynamic toroidal field tension force that halts the eruption. Lastly, this magnetic tension force is missing from existing eruption models, which is why such models cannot explain or predict failed torus events.« less

A dynamic magnetic tension force as the cause of failed solar eruptions

DOE PAGES

Myers, Clayton E.; Yamada, Masaaki; Ji, Hantao; ...

2015-12-23

Coronal mass ejections are solar eruptions driven by a sudden release of magnetic energy stored in the Sun's corona. In many cases, this magnetic energy is stored in long-lived, arched structures called magnetic flux ropes. When a flux rope destabilizes, it can either erupt and produce a coronal mass ejection or fail and collapse back towards the Sun. The prevailing belief is that the outcome of a given event is determined by a magnetohydrodynamic force imbalance called the torus instability. This belief is challenged, however, by observations indicating that torus-unstable flux ropes sometimes fail to erupt. This contradiction has notmore » yet been resolved because of a lack of coronal magnetic field measurements and the limitations of idealized numerical modelling. In this paper, we report the results of a laboratory experiment that reveal a previously unknown eruption criterion below which torus-unstable flux ropes fail to erupt. We find that such 'failed torus' events occur when the guide magnetic field (that is, the ambient field that runs toroidally along the flux rope) is strong enough to prevent the flux rope from kinking. Under these conditions, the guide field interacts with electric currents in the flux rope to produce a dynamic toroidal field tension force that halts the eruption. Lastly, this magnetic tension force is missing from existing eruption models, which is why such models cannot explain or predict failed torus events.« less

Improvement of persistent magnetic field trapping in bulk Y-Ba-Cu-O superconductors

NASA Technical Reports Server (NTRS)

Chen, In-Gann; Weinstein, Roy

1993-01-01

For type-II superconductors, magnetic field can be trapped due to persistent internal supercurrent. Quasi-persistent magnetic fields near 2 T at 60 K (and 1.4 T at 77 K) have been measured in minimagnets made of proton-irradiated melt-textured Y-Ba-Cu-O (MT-Y123) samples. Using the trapping effect, high-field permanent magnets with dipole, quadrupole, or more complicated configurations can be made of existing MT-Y123 material, thus bypassing the need for high-temperature superconductor (HTS) wires. A phenomenological current model has been developed to account for the trapped field intensity and profile in HTS samples. This model is also a guide to select directions of materials development to further improve field trapping properties. General properties such as magnetic field intensities, spatial distributions, stabilities, and temperature dependence of trapped field are discussed.

The Properties of Reconnection Current Sheets in GRMHD Simulations of Radiatively Inefficient Accretion Flows

NASA Astrophysics Data System (ADS)

Ball, David; Özel, Feryal; Psaltis, Dimitrios; Chan, Chi-Kwan; Sironi, Lorenzo

2018-02-01

Non-ideal magnetohydrodynamic (MHD) effects may play a significant role in determining the dynamics, thermal properties, and observational signatures of radiatively inefficient accretion flows onto black holes. In particular, particle acceleration during magnetic reconnection events may influence black hole spectra and flaring properties. We use representative general relativistic magnetohydrodynamic (GRMHD) simulations of black hole accretion flows to identify and explore the structures and properties of current sheets as potential sites of magnetic reconnection. In the case of standard and normal evolution (SANE) disks, we find that in the reconnection sites, the plasma beta ranges from 0.1 to 1000, the magnetization ranges from 10‑4 to 1, and the guide fields are weak compared with the reconnecting fields. In magnetically arrested (MAD) disks, we find typical values for plasma beta from 10‑2 to 103, magnetizations from 10‑3 to 10, and typically stronger guide fields, with strengths comparable to or greater than the reconnecting fields. These are critical parameters that govern the electron energy distribution resulting from magnetic reconnection and can be used in the context of plasma simulations to provide microphysics inputs to global simulations. We also find that ample magnetic energy is available in the reconnection regions to power the fluence of bright X-ray flares observed from the black hole in the center of the Milky Way.

Transport characteristics of nanoparticle-based ferrofluids in a gel model of the brain

PubMed Central

Basak, Soubir; Brogan, David; Dietrich, Hans; Ritter, Rogers; Dacey, Ralph G; Biswas, Pratim

2009-01-01

A current advance in nanotechnology is the selective targeting of therapeutics by external magnetic field-guided delivery. This is an important area of research in medicine. The use of magnetic forces results in the formation of agglomerated structures in the field region. The transport characteristics of these agglomerated structures are explored. A nonintrusive method based on in situ light-scattering techniques is used to characterize the velocity of such particles in a magnetic field gradient. A transport model for the chain-like agglomerates is developed based on these experimental observations. The transport characteristics of magnetic nanoparticle drug carriers are then explored in gel-based simulated models of the brain. Results of such measurements demonstrate decreased diffusion of magnetic nanoparticles when placed in a high magnetic field gradient. PMID:19421367

Particle Demagnetization in Collisionless Magnetic Reconnection

NASA Technical Reports Server (NTRS)

Hesse, Michael

2006-01-01

The dissipation mechanism of magnetic reconnection remains a subject of intense scientific interest. On one hand, one set of recent studies have shown that particle inertia-based processes, which include thermal and bulk inertial effects, provide the reconnection electric field in the diffusion region. In this presentation, we present analytical theory results, as well as 2.5 and three-dimensional PIC simulations of guide field magnetic reconnection. We will show that diffusion region scale sizes in moderate and large guide field cases are determined by electron Larmor radii, and that analytical estimates of diffusion region dimensions need to include description of the heat flux tensor. The dominant electron dissipation process appears to be based on thermal electron inertia, expressed through nongyrotropic electron pressure tensors. We will argue that this process remains viable in three dimensions by means of a detailed comparison of high resolution particle-in-cell simulations.

Life on Magnets: Stem Cell Networking on Micro-Magnet Arrays

PubMed Central

Zablotskii, Vitalii; Dejneka, Alexandr; Kubinová, Šárka; Le-Roy, Damien; Dumas-Bouchiat, Frédéric; Givord, Dominique; Dempsey, Nora M.; Syková, Eva

2013-01-01

Interactions between a micro-magnet array and living cells may guide the establishment of cell networks due to the cellular response to a magnetic field. To manipulate mesenchymal stem cells free of magnetic nanoparticles by a high magnetic field gradient, we used high quality micro-patterned NdFeB films around which the stray field’s value and direction drastically change across the cell body. Such micro-magnet arrays coated with parylene produce high magnetic field gradients that affect the cells in two main ways: i) causing cell migration and adherence to a covered magnetic surface and ii) elongating the cells in the directions parallel to the edges of the micro-magnet. To explain these effects, three putative mechanisms that incorporate both physical and biological factors influencing the cells are suggested. It is shown that the static high magnetic field gradient generated by the micro-magnet arrays are capable of assisting cell migration to those areas with the strongest magnetic field gradient, thereby allowing the build up of tunable interconnected stem cell networks, which is an elegant route for tissue engineering and regenerative medicine. PMID:23936425

Magnetic attachment mechanism

NASA Technical Reports Server (NTRS)

Harwell, William D. (Inventor); Wu, Mitchell B. (Inventor)

1990-01-01

A magnetic attachment mechanism adapted for interfacing with the manipulator arm (11) of a remote manipulator system and comprising a pair of permanent magnets (31,32) of rare earth material which are arranged in a stator-rotor relationship. The rotor magnet (32), is journalled for rotation about its longitudinal axis between pole plates (35,36) of the stator magnet (31), each of which includes an adhering surface (35a,36a). In a first rotary position corresponding to the ON condition, each of the poles of the rotor magnet (32) is closely adjacent a stator magnet pole plate of like polarity whereby the respective magnet fields are additive for producing a strong magnetic field emanating from the adhering surfaces (35a,36a) for attracting a ferrous magnetic plate 20, or the like, affixed to the payload (20 or 50). When the rotor magnet (32) is rotated to a second position corresponding to the OFF condition, each of the poles of the rotor magnet (31) is disposed closely adjacent a pole plate of unlike polarity whereby the magnetic fields of the magnets are in cancelling relationship at the adhering surfaces (35a,36a) which permits the release of a payload. An actuator (51 or 70) for selectively rotating the rotor magnet (32) between the ON and OFF positions is provided for interfacing and connecting the magnetic attachment mechanism with a manipulator arm. For effecting an optimal rigidized attachment the payload is provided with guides (91,92) cooperable with guides (96,16,17) on the housing of the mechanism for directing adhering surfaces (35a,36a) of the polar plates to the ferrous plate (20).

Means for counteracting charged particle beam divergence

DOEpatents

Hooper, Jr., Edwin B.

1978-01-01

To counteract charge particle beam divergence, magnetic field-generating means are positioned along the edges of a charged particle beam to be controlled, such as to deflect and redirect particles tending to diverge from a desired beam direction. By selective arrangement of the magnetic field-generating means, the entire beam may be deflected and guided into different directions.

Guided and magnetic self-assembly of tunable magnetoceptive gels

NASA Astrophysics Data System (ADS)

Tasoglu, S.; Yu, C. H.; Gungordu, H. I.; Guven, S.; Vural, T.; Demirci, U.

2014-09-01

Self-assembly of components into complex functional patterns at microscale is common in nature, and used increasingly in numerous disciplines such as optoelectronics, microfabrication, sensors, tissue engineering and computation. Here, we describe the use of stable radicals to guide the self-assembly of magnetically tunable gels, which we call ‘magnetoceptive’ materials at the scale of hundreds of microns to a millimeter, each can be programmed by shape and composition, into heterogeneous complex structures. Using paramagnetism of free radicals as a driving mechanism, complex heterogeneous structures are built in the magnetic field generated by permanent magnets. The overall magnetic signature of final structure is erased via an antioxidant vitamin E, subsequent to guided self-assembly. We demonstrate unique capabilities of radicals and antioxidants in fabrication of soft systems with heterogeneity in material properties, such as porosity, elastic modulus and mass density; then in bottom-up tissue engineering and finally, levitational and selective assembly of microcomponents.

Guided and magnetic self-assembly of tunable magnetoceptive gels

PubMed Central

Tasoglu, S.; Yu, C.H.; Gungordu, H.I.; Guven, S.; Vural, T.; Demirci, U.

2014-01-01

Self-assembly of components into complex functional patterns at microscale is common in nature, and used increasingly in numerous disciplines such as optoelectronics, microfabrication, sensors, tissue engineering and computation. Here, we describe the use of stable radicals to guide the self-assembly of magnetically tunable gels, which we call ‘magnetoceptive’ materials at the scale of hundreds of microns to a millimeter, each can be programmed by shape and composition, into heterogeneous complex structures. Using paramagnetism of free radicals as a driving mechanism, complex heterogeneous structures are built in the magnetic field generated by permanent magnets. The overall magnetic signature of final structure is erased via an antioxidant vitamin E, subsequent to guided self-assembly. We demonstrate unique capabilities of radicals and antioxidants in fabrication of soft systems with heterogeneity in material properties, such as porosity, elastic modulus and mass density; then in bottom-up tissue engineering and finally, levitational and selective assembly of microcomponents. PMID:25175148

Computational studies of steering nanoparticles with magnetic gradients

NASA Astrophysics Data System (ADS)

Aylak, Sultan Suleyman

Magnetic Resonance Imaging (MRI) guided nanorobotic systems that could perform diagnostic, curative, and reconstructive treatments in the human body at the cellular and subcellular level in a controllable manner have recently been proposed. The concept of a MRI-guided nanorobotic system is based on the use of a MRI scanner to induce the required external driving forces to guide magnetic nanocapsules to a specific target. However, the maximum magnetic gradient specifications of existing clinical MRI systems are not capable of driving magnetic nanocapsules against the blood flow. This thesis presents the visualization of nanoparticles inside blood vessel, Graphical User Interface (GUI) for updating file including initial parameters and demonstrating the simulation of particles and C++ code for computing magnetic forces and fluidic forces. The visualization and GUI were designed using Virtual Reality Modeling Language (VRML), MATLAB and C#. The addition of software for MRI-guided nanorobotic system provides simulation results. Preliminary simulation results demonstrate that external magnetic field causes aggregation of nanoparticles while they flow in the vessel. This is a promising result --in accordance with similar experimental results- and encourages further investigation on the nanoparticle-based self-assembly structures for use in nanorobotic drug delivery.

Open-loop correction for an eddy current dominated beam-switching magnet.

PubMed

Koseki, K; Nakayama, H; Tawada, M

2014-04-01

A beam-switching magnet and the pulsed power supply it requires have been developed for the Japan Proton Accelerator Research Complex. To switch bunched proton beams, the dipole magnetic field must reach its maximum value within 40 ms. In addition, the field flatness should be less than 5 × 10(-4) to guide each bunched beam to the designed orbit. From a magnetic field measurement by using a long search coil, it was found that an eddy current in the thick endplates and laminated core disturbs the rise of the magnetic field. The eddy current also deteriorates the field flatness over the required flat-top period. The measured field flatness was 5 × 10(-3). By using a double-exponential equation to approximate the measured magnetic field, a compensation pattern for the eddy current was calculated. The integrated magnetic field was measured while using the newly developed open-loop compensation system. A field flatness of less than 5 × 10(-4), which is an acceptable value, was achieved.

Open-loop correction for an eddy current dominated beam-switching magnet

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koseki, K., E-mail: kunio.koseki@kek.jp; Nakayama, H.; Tawada, M.

2014-04-15

A beam-switching magnet and the pulsed power supply it requires have been developed for the Japan Proton Accelerator Research Complex. To switch bunched proton beams, the dipole magnetic field must reach its maximum value within 40 ms. In addition, the field flatness should be less than 5 × 10{sup −4} to guide each bunched beam to the designed orbit. From a magnetic field measurement by using a long search coil, it was found that an eddy current in the thick endplates and laminated core disturbs the rise of the magnetic field. The eddy current also deteriorates the field flatness over the requiredmore » flat-top period. The measured field flatness was 5 × 10{sup −3}. By using a double-exponential equation to approximate the measured magnetic field, a compensation pattern for the eddy current was calculated. The integrated magnetic field was measured while using the newly developed open-loop compensation system. A field flatness of less than 5 × 10{sup −4}, which is an acceptable value, was achieved.« less

Towards an electro-magnetic field separation of deposited material implemented in an ion beam sputter process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Malobabic, Sina; Jupe, Marco; Ristau, Detlev

Nowadays, Ion Beam Sputter (IBS) processes are very well optimized on an empirical basis. To achieve further progresses, a modification of the IBS process by guiding the coating material using an axial magnetic field and an additional electrical field has been studied. The electro-magnetic (EM) field leads to a significant change in plasma properties and deposition rate distributions, whereas an increase in deposition rate along the centerline of the axial EM field around 150% was observed. These fundamental studies on the prototype are the basis for the development of an applicable and workable design of a separation device.

Formation and Reconnection of Three-dimensional Current Sheets with a Guide Field in the Solar Corona

NASA Astrophysics Data System (ADS)

Edmondson, J. K.; Lynch, B. J.

2017-11-01

We analyze a series of three-dimensional magnetohydrodynamic numerical simulations of magnetic reconnection in a model solar corona to study the effect of the guide-field component on quasi-steady-state interchange reconnection in a pseudostreamer arcade configuration. This work extends the analysis of Edmondson et al. by quantifying the mass density enhancement coherency scale in the current sheet associated with magnetic island formation during the nonlinear phase of plasmoid-unstable reconnection. We compare the results of four simulations of a zero, weak, moderate, and a strong guide field, {B}{GF}/{B}0=\\{0.0,0.1,0.5,1.0\\}, to quantify the plasmoid density enhancement’s longitudinal and transverse coherency scales as a function of the guide-field strength. We derive these coherency scales from autocorrelation and wavelet analyses, and demonstrate how these scales may be used to interpret the density enhancement fluctuation’s Fourier power spectra in terms of a structure formation range, an energy continuation range, and an inertial range—each population with a distinct spectral slope. We discuss the simulation results in the context of solar and heliospheric observations of pseudostreamer solar wind outflow and possible signatures of reconnection-generated structure.

All fiber magnetic field sensor with Ferrofluid-filled tapered microstructured optical fiber interferometer.

PubMed

Deng, Ming; Huang, Can; Liu, Danhui; Jin, Wei; Zhu, Tao

2015-08-10

An ultra-compact optical fiber magnetic field sensor based on a microstructured optical fiber (MOF) modal interference and ferrofluid (FF) has been proposed and experimentally demonstrated. The magnetic field sensor was fabricated by splicing a tapered germanium-doped index guided MOF with six big holes injected with FF to two conventional single-mode fibers. The transmission spectra of the proposed sensor under different magnetic field intensities have been measured and theoretically analyzed. Due to an efficient interaction between the magnetic nanoparticles in FF and the excited cladding mode, the magnetic field sensitivity reaches up to117.9pm/mT with a linear range from 0mT to 30mT. Moreover, the fabrication process of the proposed sensor is simple, easy and cost-effective. Therefore, it will be a promising candidate for military, aviation industry, and biomedical applications, especially, for the applications where the space is limited.

EMF Rapid Program Engineering Projects, Project 1, Development of Recommendations for Guidelines for Field Source Measurement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Electric Research and Management, Inc.

1997-03-11

The goal of this project is to develop a protocol for measuring the electric and magnetic fields around sources. Data from these measurements may help direct future biological effects research by better defining the complexity of magnetic and electric fields to which humanity is exposed, as well asprovide the basis for rigorous field exposure analysis and risk assessment once the relationship between field exposure and biological response. is better understood. The data base also should have sufficient spatial and temporal characteristics to guide electric and magnetic field management. The goal of Task A is to construct a set of characteristicsmore » that would be ideal to have for guiding and interpreting biological studies and for focusing any future effort at field management. This ideal set will then be quantified and reduced according to the availability (or possible development of) instrumentation to measure the desired characteristics. Factors that also will be used to define pragmatic data sets will be the cost of collecting the data, the cost of developing an adequate data base, and the needed precision in measuring specific characteristics. A field, electric or magnetic, will always be ,some function of time and space. The first step in this section of the protocol development will be to determine what span of time and what portion of space are required to quantify the electric and magnetic fields around sources such as appliances and electrical apparatus. Constraints on time will be set by examining measurement limitations and biological data requirements.« less

Non-ideal energy conversion during asymmetric magnetic reconnection with a moderate guide field

NASA Astrophysics Data System (ADS)

Genestreti, K. J.; Varsani, A.; Hesse, M.; Torbert, R. B.; Burch, J.; Cassak, P.; Ergun, R.; Phan, T.; Nakamura, R.; Giles, B. L.; Schwartz, S. J.; Wang, S.; Toledo Redondo, S.; Hwang, K. J.; Laignel, B.; Escoubet, C. P.; Fear, R. C.; Khotyaintsev, Y. V.

2017-12-01

Using data from NASA's Magnetospheric Multiscale (MMS) mission, we investigate the local (in time and space) rate of work done by the non-ideal electric field on the plasma during a crossing through the magnetopause reconnection region. The four MMS spacecraft were in a tight tetrahedral formation ( 7 km separation) and observed several ion and electron-scale signatures of asymmetric reconnection, one of which was J.E' (=J.(E+vexB))>0. The data indicate that the magnetic field was expending energy both (1) near the magnetosphere-side separator, where the current was carried by counter-streaming electrons with crescent-shaped velocity distribution functions, and (2) near the magnetic X-point, where the current was carried by accelerated inflowing magnetosheath electrons moving against the guide field. Near the X-point, the current-aligned portion of the non-ideal electric field is largely a result of electron pressure divergence. We further investigate the pressure tensor divergence, separating the components from in and out-of-the-plane gradients as well as gyrotropic and non-gyrotropic pressures.

Magnetic helicity balance at Taylor relaxed states sustained by AC helicity injection

NASA Astrophysics Data System (ADS)

Hirota, Makoto; Morrison, Philip J.; Horton, Wendell; Hattori, Yuji

2017-10-01

Magnitudes of Taylor relaxed states that are sustained by AC magnetic helicity injection (also known as oscillating field current drive, OFCD) are investigated numerically in a cylindrical geometry. Compared with the amplitude of the oscillating magnetic field at the skin layer (which is normalized to 1), the strength of the axial guide field Bz 0 is shown to be an important parameter. The relaxation process seems to be active only when Bz 0 < 1 . Moreover, in the case of weak guide field Bz 0 < 0.2 , a helically-symmetric relaxed state is self-generated instead of the axisymmetric reversed-field pinch. As a theoretical model, the helicity balance is considered in a similar way to R. G. O'Neill et al., where the helicity injection rate is directly equated with the dissipation rate at the Taylor states. Then, the bifurcation to the helical Taylor state is predicted theoretically and the estimated magnitudes of the relaxed states reasonably agree with numerical results as far as Bz 0 < 1 . This work was supported by JSPS KAKENHI Grant Number 16K05627.

Scaling of Electron Heating During Magnetic Reconnection

NASA Astrophysics Data System (ADS)

Ohia, O.; Le, A.; Daughton, W. S.; Egedal, J.

2016-12-01

While magnetic reconnection plays a major role in accelerating and heating magnetospheric plasma, it remains poorly understood how the level of particle energization depends on the plasma conditions. Meanwhile, a recent survey of THEMIS magnetopause reconnection observations [Phan et al. GRL 2013] and a numerical study [Shay et al. PoP 2014] found empirically that the electron heating scales with the square of the upstream Alfven speed. Equivalently for weak guide fields, the fractional electron temperature increase is inversely proportional to the upstream electron beta (ratio of electron to magnetic pressure). We present models for symmetric reconnection with moderate [Ohia et al., GRL 2015] or zero guide field that predict the electron bulk heating. In the models, adiabatically trapped electrons gain energy from parallel electric fields in the inflowing region. For purely anti-parallel reconnection, meandering electrons receive additional energy from the reconnection electric field. The predicted scalings are in quantitative agreement with fluid and kinetic simulations, as well as spacecraft observations. Using kinetic simulations, we extend this work to explore how the layer dynamics and electron bulk heating vary as functions of the magnetic shear and plasma and magnetic pressure asymmetry across the reconnection layer. These results are pertinent to recent Magnetospheric Multiscale (MMS) Mission measurements of electron dynamics during dayside magnetopause reconnection.

Development of high-resolution two-dimensional magnetic field measurement system by use of printed-circuit technology

NASA Astrophysics Data System (ADS)

Akimitsu, Moe; Qinghong, Cao; Sawada, Asuka; Hatano, Hironori; Tanabe, Hiroshi; Ono, Yasushi; TS-Group Team

2017-10-01

We have developed a new-types of high-resolution magnetic probe array for our new magnetic reconnection experiments: TS-3U (ST, FRC: R =0.2m, 2017-) and TS-4U (ST, FRC: R =0.5m, 2018-), using the advanced printed-circuit technology. They are equipped with all three-components of magnetic pick-up coils whose size is 1-5mm x 3mm. Each coil is composed of two-sided coil pattern with line width of 0.05mm. We can install two or three printed arrays in a single glass (ceramic) tube for two or three component measurements. Based on this new probe technique, we started high-resolution and high-accuracy measurement of the current sheet thickness and studied its plasma parameter dependence. We found that the thickness of current sheet increases inversely with the guide toroidal field. It is probably determined by the ion gyroradius in agreement with the particle simulation by Horiuchi etc. While the reconnection speed is steady under low guide field condition, it is observed to oscillate in the specific range of guide field, suggesting transition from the quasi-steady reconnection to the intermittent reconnection. Cause and mechanism for intermittent reconnection will be discussed using the current sheet dissipation and dynamic balance between plasma inflow and outflow. This work supported by JSPS KAKENHI Grant Numbers 15H05750, 15K14279 and 17H04863.

Safety of High Speed Guided Ground Transportation Systems : Review of Existing EMF Guidelines, Standards and Regulations

DOT National Transportation Integrated Search

1993-08-01

To assess the state of knowledge about anticipated electric and magnetic field (EMF) exposures from electrical transportation systems, including electrically powered rail and magnetically levitated (maglev), research concerning biological effects of ...

The Onset of Magnetic Reconnection: Tearing Instability in Current Sheets with a Guide Field

NASA Astrophysics Data System (ADS)

Daldorff, L. K. S.; Klimchuk, J. A.; Knizhnik, K. J.

2016-12-01

Magnetic reconnection is fundamental to many solar phenomena, ranging from coronal heating, to jets, to flares and CMEs. A poorly understood yet crucial aspect of reconnection is that it does not occur until magnetic stresses have built to sufficiently high levels for significant energy release. If reconnection were to happen too soon, coronal heating would be weak and flares would be small. As part of our program to study the onset conditions for magnetic reconnection, we have investigated the instability of current sheets to tearing. Surprisingly little work has been done on this problem for sheets that include a guide field, i.e., for which the field rotates by less than 180 degrees. This is the most common situation on the Sun. We present numerical 3D resistive MHD simulations of several sheets and show how the behaviour depends on the shear angle (rotation). We compare our results to the predictions of linear theory and discuss the nonlinear evolution in terms of plasmoid formation and the interaction of different oblique tearing modes. The relevance to the Sun is explained.

The Diffusion Region in Collisionless Magnetic Reconnection

NASA Technical Reports Server (NTRS)

Hesse, Michael; Neukirch, Thomas; Schindler, Karl; Kuznetsova, Masha; Zenitani, Seiji

2011-01-01

A review of present understanding of the dissipation region in magnetic reconnection is presented. The review focuses on results of the thermal inertia-based dissipation mechanism but alternative mechanisms are mentioned as well. For the former process, a combination of analytical theory and numerical modeling is presented. Furthermore, a new relation between the electric field expressions for anti-parallel and guide field reconnection is developed.

Polarization switching of sodium guide star laser for brightness enhancement

NASA Astrophysics Data System (ADS)

Fan, Tingwei; Zhou, Tianhua; Feng, Yan

2016-07-01

The efficiency of optical pumping that enhances the brightness of sodium laser guide star with circularly polarized light is reduced substantially due to the precession of sodium atoms in geomagnetic field. Switching the laser between left and right circular polarization at the Larmor frequency is proposed to improve the photon return. With ESO's cw laser guide star system at Paranal as example, numerical simulation for both square-wave and sine-wave polarization modulation is conducted. For the square-wave switching case, the return flux is increased when the angle between geomagnetic field and laser beam is larger than 60°, as much as 40% at 90°. The method can also be applied for remote measurement of magnetic field with available cw guide star laser.

Magnetic Nozzle and Plasma Detachment Experiment

NASA Technical Reports Server (NTRS)

Chavers, Gregory; Dobson, Chris; Jones, Jonathan; Martin, Adam; Bengtson, Roger D.; Briezman, Boris; Arefiev, Alexey; Cassibry, Jason; Shuttpelz, Branwen; Deline, Christopher

2006-01-01

High power plasma propulsion can move large payloads for orbit transfer (such as the ISS), lunar missions, and beyond with large savings in fuel consumption owing to the high specific impulse. At high power, lifetime of the thruster becomes an issue. Electrodeless devices with magnetically guided plasma offer the advantage of long life since magnetic fields confine the plasma radially and keep it from impacting the material surfaces. For decades, concerns have been raised about the plasma remaining attached to the magnetic field and returning to the vehicle along the closed magnetic field lines. Recent analysis suggests that this may not be an issue of the magnetic field is properly shaped in the nozzle region and the plasma has sufficient energy density to stretch the magnetic field downstream. An experiment was performed to test the theory regarding the Magneto-hydrodynamic (MHD) detachment scenario. Data from this experiment will be presented. The Variable Specific Impulse Magnetoplasma Rocket (VASIMR) being developed by the Ad Astra Rocket Company uses a magnetic nozzle as described above. The VASIMR is also a leading candidate for exploiting an electric propulsion test platform being considered for the ISS.

Strongly magnetized classical plasma models

NASA Technical Reports Server (NTRS)

Montgomery, D. C.

1972-01-01

The class of plasma processes for which the so-called Vlasov approximation is inadequate is investigated. Results from the equilibrium statistical mechanics of two-dimensional plasmas are derived. These results are independent of the presence of an external dc magnetic field. The nonequilibrium statistical mechanics of the electrostatic guiding-center plasma, a two-dimensional plasma model, is discussed. This model is then generalized to three dimensions. The guiding-center model is relaxed to include finite Larmor radius effects for a two-dimensional plasma.

2010 AUGUST 1-2 SYMPATHETIC ERUPTIONS. I. MAGNETIC TOPOLOGY OF THE SOURCE-SURFACE BACKGROUND FIELD

DOE Office of Scientific and Technical Information (OSTI.GOV)

Titov, V. S.; Mikic, Z.; Toeroek, T.

2012-11-01

A sequence of apparently coupled eruptions was observed on 2010 August 1-2 by Solar Dynamics Observatory and STEREO. The eruptions were closely synchronized with one another, even though some of them occurred at widely separated locations. In an attempt to identify a plausible reason for such synchronization, we study the large-scale structure of the background magnetic configuration. The coronal field was computed from the photospheric magnetic field observed at the appropriate time period by using the potential field source-surface model. We investigate the resulting field structure by analyzing the so-called squashing factor calculated at the photospheric and source-surface boundaries, asmore » well as at different coronal cross-sections. Using this information as a guide, we determine the underlying structural skeleton of the configuration, including separatrix and quasi-separatrix surfaces. Our analysis reveals, in particular, several pseudo-streamers in the regions where the eruptions occurred. Of special interest to us are the magnetic null points and separators associated with the pseudo-streamers. We propose that magnetic reconnection triggered along these separators by the first eruption likely played a key role in establishing the assumed link between the sequential eruptions. The present work substantiates our recent simplified magnetohydrodynamic model of sympathetic eruptions and provides a guide for further deeper study of these phenomena. Several important implications of our results for the S-web model of the slow solar wind are also addressed.« less

Test-electron analysis of the magnetic reconnection topology

NASA Astrophysics Data System (ADS)

Borgogno, D.; Perona, A.; Grasso, D.

2017-12-01

Three-dimensional (3D) investigations of the magnetic reconnection field topology in space and laboratory plasmas have identified the abidance of magnetic coherent structures in the stochastic region, which develop during the nonlinear stage of the reconnection process. Further analytical and numerical analyses highlighted the efficacy of some of these structures in limiting the magnetic transport. The question then arises as to what is the possible role played by these patterns in the dynamics of the plasma particles populating the chaotic region. In order to explore this aspect, we provide a detailed description of the nonlinear 3D magnetic field topology in a collisionless magnetic reconnection event with a strong guide field. In parallel, we study the evolution of a population of test electrons in the guiding-center approximation all along the reconnection process. In particular, we focus on the nonlinear spatial redistribution of the initially thermal electrons and show how the electron dynamics in the stochastic region depends on the sign and on the value of their velocities. While the particles with the highest positive speed populate the coherent current structures that survive in the chaotic sea, the presence of the manifolds calculated in the stochastic region defines the confinement area for the electrons with the largest negative velocity. These results stress the link between the magnetic topology and the electron motion and contribute to the overall picture of a non-stationary fluid magnetic reconnection description in a geometry proper to physical systems where the effects of the curvature can be neglected.

A guided enquiry approach to introduce basic concepts concerning magnetic hysteresis to minimize student misconceptions

NASA Astrophysics Data System (ADS)

Wei, Yajun; Zhai, Zhaohui; Gunnarsson, Klas; Svedlindh, Peter

2014-11-01

Basic concepts concerning magnetic hysteresis are of vital importance in understanding magnetic materials. However, these concepts are often misinterpreted by many students and even textbooks. We summarize the most common misconceptions and present a new approach to help clarify these misconceptions and enhance students’ understanding of the hysteresis loop. In this approach, students are required to perform an experiment and plot the measured magnetization values and thereby calculated demagnetizing field, internal field, and magnetic induction as functions of the applied field point by point on the same graph. The concepts of the various coercivity, remanence, saturation magnetization, and saturation induction will not be introduced until this stage. By plotting this graph, students are able to interlink all the preceding concepts and intuitively visualize the underlying physical relations between them.

High-performance iron oxide nanoparticles for magnetic particle imaging - guided hyperthermia (hMPI)

NASA Astrophysics Data System (ADS)

Bauer, Lisa M.; Situ, Shu F.; Griswold, Mark A.; Samia, Anna Cristina S.

2016-06-01

Magnetic particle imaging (MPI) is an emerging imaging modality that allows the direct and quantitative mapping of iron oxide nanoparticles. In MPI, the development of tailored iron oxide nanoparticle tracers is paramount to achieving high sensitivity and good spatial resolution. To date, most MPI tracers being developed for potential clinical applications are based on spherical undoped magnetite nanoparticles. For the first time, we report on the systematic investigation of the effects of changes in chemical composition and shape anisotropy on the MPI performance of iron oxide nanoparticle tracers. We observed a 2-fold enhancement in MPI signal through selective doping of magnetite nanoparticles with zinc. Moreover, we demonstrated focused magnetic hyperthermia heating by adapting the field gradient used in MPI. By saturating the iron oxide nanoparticles outside of a field free region (FFR) with an external static field, we can selectively heat a target region in our test sample. By comparing zinc-doped magnetite cubic nanoparticles with undoped spherical nanoparticles, we could show a 5-fold improvement in the specific absorption rate (SAR) in magnetic hyperthermia while providing good MPI signal, thereby demonstrating the potential for high-performance focused hyperthermia therapy through an MPI-guided approach (hMPI).Magnetic particle imaging (MPI) is an emerging imaging modality that allows the direct and quantitative mapping of iron oxide nanoparticles. In MPI, the development of tailored iron oxide nanoparticle tracers is paramount to achieving high sensitivity and good spatial resolution. To date, most MPI tracers being developed for potential clinical applications are based on spherical undoped magnetite nanoparticles. For the first time, we report on the systematic investigation of the effects of changes in chemical composition and shape anisotropy on the MPI performance of iron oxide nanoparticle tracers. We observed a 2-fold enhancement in MPI signal through selective doping of magnetite nanoparticles with zinc. Moreover, we demonstrated focused magnetic hyperthermia heating by adapting the field gradient used in MPI. By saturating the iron oxide nanoparticles outside of a field free region (FFR) with an external static field, we can selectively heat a target region in our test sample. By comparing zinc-doped magnetite cubic nanoparticles with undoped spherical nanoparticles, we could show a 5-fold improvement in the specific absorption rate (SAR) in magnetic hyperthermia while providing good MPI signal, thereby demonstrating the potential for high-performance focused hyperthermia therapy through an MPI-guided approach (hMPI). Electronic supplementary information (ESI) available: Detailed IONP synthetic methods, description of magnetic particle relaxometer set-up, TEM of reference IONP (Senior Scientific PrecisionMRX™ 25 nm oleic acid-coated nanoparticles), concentration dependent PSF of all IONP samples, PSF and SAR of Zn-Sph and Zn-Cube mixture sample, upper right quadrant of field-dependent hysteresis curve labelled with static field strengths, and the magnetic hyperthermia temperature profiles with and without the presence of external magnetic fields. See DOI: 10.1039/c6nr01877g

Student representation of magnetic field concepts in learning by guided inquiry

NASA Astrophysics Data System (ADS)

Desy Fatmaryanti, Siska; Suparmi; Sarwanto; Ashadi

2017-01-01

The purpose of this study was to determine the change of student’s representation after the intervention of learning by guided inquiry. The population in this research were all students who took a fundamental physics course, consisted of 28 students academic year 2016, Department of Physics Education, Faculty of Teacher Training and Education, University of Muhammadiyah Purworejo. This study employed a quasi-experimental design with group pre-test and post-test. The result of the research showed that the average of students representation of magnetic field before implementation of guided inquiry was 28,6 % and after implementation was 71,4%. It means that the student’s ability of multi-representation increase. Moreover, the number of students who is able to write and draw based on experiment data increased from 10,7% to 21,4 %. It was also showed that the number of student with no answer decreased from 28,5% to 10,7%.

Magnetic information affects the stellar orientation of young bird migrants

NASA Astrophysics Data System (ADS)

Weindler, Peter; Wiltschko, Roswitha; Wiltschko, Wolfgang

1996-09-01

WHEN young birds leave on their first migration, they are guided by innate information about their direction of migration. It is generally assumed that this direction is represented twice, namely with respect to celestial rotation and with respect to the Earth's magnetic field1,2. The interactions between the two cue systems have been analysed by exposing hand-raised young birds during the premigratory period to cue-conflict situations, in which celestial rotation and the magnetic field provided different information. Celestial rotation altered the course with respect to the magnetic field3-7, whereas conflicting magnetic information did not seem to affect the course with respect to the stars8,9. Celestial information thus seemed to dominate over magnetic information. Here we report that the interaction between the two cue systems is far more complex than this. Celestial rotation alone seems to provide only a tendency to move away from its centre (towards geographical south), which is then modified by information from the magnetic field to establish the distinctive, population-specific migratory direction.

Numerical simulation of magnetic nanoparticles targeting in a bifurcation vessel

NASA Astrophysics Data System (ADS)

Larimi, M. M.; Ramiar, A.; Ranjbar, A. A.

2014-08-01

Guiding magnetic iron oxide nanoparticles with the help of an external magnetic field to its target is the principle behind the development of super paramagnetic iron oxide nanoparticles (SPIONs) as novel drug delivery vehicles. The present paper is devoted to study on MDT (Magnetic Drug Targeting) technique by particle tracking in the presence of magnetic field in a bifurcation vessel. The blood flow in bifurcation is considered incompressible, unsteady and Newtonian. The flow analysis applies the time dependent, two dimensional, incompressible Navier-Stokes equations for Newtonian fluids. The Lagrangian particle tracking is performed to estimate particle behavior under influence of imposed magnetic field gradients along the bifurcation. According to the results, the magnetic field increased the volume fraction of particle in target region, but in vessels with high Reynolds number, the efficiency of MDT technique is very low. Also the results showed that in the bifurcation vessels with lower angles, wall shear stress is higher and consequently the risk of the vessel wall rupture increases.

Electron heating in the exhaust of magnetic reconnection with negligible guide field

NASA Astrophysics Data System (ADS)

Wang, Shan; Chen, Li-Jen; Bessho, Naoki; Kistler, Lynn M.; Shuster, Jason R.; Guo, Ruilong

2016-03-01

Electron heating in the magnetic reconnection exhaust is investigated with particle-in-cell simulations, space observations, and theoretical analysis. Spatial variations of the electron temperature (Te) and associated velocity distribution functions (VDFs) are examined and understood in terms of particle energization and randomization processes that vary with exhaust locations. Inside the electron diffusion region (EDR), the electron temperature parallel to the magnetic field (Te∥) exhibits a local minimum and the perpendicular temperature (Te⊥) shows a maximum at the current sheet midplane. In the intermediate exhaust downstream from the EDR and far from the magnetic field pileup region, Te⊥/Te∥ is close to unity and Te is approximately uniform, but the VDFs are structured: close to the midplane, VDFs are quasi-isotropic, whereas farther away from the midplane, VDFs exhibit field-aligned beams directed toward the midplane. In the far exhaust, Te generally increases toward the midplane and the pileup region, and the corresponding VDFs show counter-streaming beams. A distinct population with low v∥ and high v⊥ is prominent in the VDFs around the midplane. Test particle results show that the magnetic curvature near the midplane produces pitch angle scattering to generate quasi-isotropic distributions in the intermediate exhaust. In the far exhaust, electrons with initial high v∥ (v⊥) are accelerated mainly through curvature (gradient-B) drift opposite to the electric field, without significant pitch angle scattering. The VDF structures predicted by simulations are observed in magnetotail reconnection measurements, indicating that the energization mechanisms captured in the reported simulations are applicable to magnetotail reconnection with negligible guide field.

An X-band high-impedance relativistic klystron amplifier with an annular explosive cathode

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhu, Danni; Zhang, Jun, E-mail: zhangjun@nudt.edu.cn; Zhong, Huihuang

2015-11-15

The feasibility of employing an annular beam instead of a solid one in the X-band high-impedance relativistic klystron amplifier (RKA) is investigated in theory and simulation. Small-signal theory analysis indicates that the optimum bunching distance, fundamental current modulation depth, beam-coupling coefficient, and beam-loaded quality factor of annular beams are all larger than the corresponding parameters of solid beams at the same beam voltage and current. An annular beam RKA and a solid beam RKA with almost the same geometric parameters are compared in particle-in-cell simulation. Output microwave power of 100 MW, gain of 50 dB, and power conversion efficiency of 42% aremore » obtained in an annular beam RKA. The annular beam needs a 15% lower uniform guiding magnetic field than the solid beam. Our investigations demonstrate that we are able to use a simple annular explosive cathode immersed in a lower uniform magnetic field instead of a solid thermionic cathode in a complicated partially shielding magnetic field for designing high-impedance RKA, which avoids high temperature requirement, complicated electron-optical system, large area convergence, high current density, and emission uniformity for the solid beam. An equivalent method for the annular beam and the solid beam on bunching features is proposed and agrees with the simulation. The annular beam has the primary advantages over the solid beam that it can employ the immersing uniform magnetic field avoiding the complicated shielding magnetic field system and needs a lower optimum guiding field due to the smaller space charge effect.« less

Extreme ultraviolet emission and confinement of tin plasmas in the presence of a magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roy, Amitava, E-mail: roy@fzu.cz, E-mail: aroy@barc.gov.in; HiLASE Project, Department of Diode-pumped Lasers, Institute of Physics of the ASCR, Na Slovance 2, 18221 Prague; Murtaza Hassan, Syed

2014-05-15

We investigated the role of a guiding magnetic field on extreme ultraviolet (EUV) and ion emission from a laser produced Sn plasma for various laser pulse duration and intensity. For producing plasmas, planar slabs of pure Sn were irradiated with 1064 nm, Nd:YAG laser pulses with varying pulse duration (5–15 ns) and intensity. A magnetic trap was fabricated with the use of two neodymium permanent magnets which provided a magnetic field strength ∼0.5 T along the plume expansion direction. Our results indicate that the EUV conversion efficiency do not depend significantly on applied axial magnetic field. Faraday Cup ion analysis of Sn plasmamore » show that the ion flux reduces by a factor of ∼5 with the application of an axial magnetic field. It was found that the plasma plume expand in the lateral direction with peak velocity measured to be ∼1.2 cm/μs and reduced to ∼0.75 cm/μs with the application of an axial magnetic field. The plume expansion features recorded using fast photography in the presence and absence of 0.5 T axial magnetic field are simulated using particle-in-cell code. Our simulation results qualitatively predict the plasma behavior.« less

Magnetic Fields of Extrasolar Planets: Planetary Interiors and Habitability

NASA Astrophysics Data System (ADS)

Lazio, T. Joseph

2018-06-01

Ground-based observations showed that Jupiter's radio emission is linked to its planetary-scale magnetic field, and subsequent spacecraft observations have shown that most planets, and some moons, have or had a global magnetic field. Generated by internal dynamos, magnetic fields are one of the few remote sensing means of constraining the properties of planetary interiors. For the Earth, its magnetic field has been speculated to be partially responsible for its habitability, and knowledge of an extrasolar planet's magnetic field may be necessary to assess its habitability. The radio emission from Jupiter and other solar system planets is produced by an electron cyclotron maser, and detections of extrasolar planetary electron cyclotron masers will enable measurements of extrasolar planetary magnetic fields. Based on experience from the solar system, such observations will almost certainly require space-based observations, but they will also be guided by on-going and near-future ground-based observations.This work has benefited from the discussion and participants of the W. M. Keck Institute of Space Studies "Planetary Magnetic Fields: Planetary Interiors and Habitability" and content within a white paper submitted to the National Academy of Science Committee on Exoplanet Science Strategy. Part of this research was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration.

Magnetic discontinuities in magnetohydrodynamic turbulence and in the solar wind.

PubMed

Zhdankin, Vladimir; Boldyrev, Stanislav; Mason, Joanne; Perez, Jean Carlos

2012-04-27

Recent measurements of solar wind turbulence report the presence of intermittent, exponentially distributed angular discontinuities in the magnetic field. In this Letter, we study whether such discontinuities can be produced by magnetohydrodynamic (MHD) turbulence. We detect the discontinuities by measuring the fluctuations of the magnetic field direction, Δθ, across fixed spatial increments Δx in direct numerical simulations of MHD turbulence with an imposed uniform guide field B(0). A large region of the probability density function (pdf) for Δθ is found to follow an exponential decay, proportional to exp(-Δθ/θ(*)), with characteristic angle θ(*)≈(14°)(b(rms)/B(0))(0.65) for a broad range of guide-field strengths. We find that discontinuities observed in the solar wind can be reproduced by MHD turbulence with reasonable ratios of b(rms)/B(0). We also observe an excess of small angular discontinuities when Δx becomes small, possibly indicating an increasing statistical significance of dissipation-scale structures. The structure of the pdf in this case closely resembles the two-population pdf seen in the solar wind. We thus propose that strong discontinuities are associated with inertial-range MHD turbulence, while weak discontinuities emerge from dissipation-range turbulence. In addition, we find that the structure functions of the magnetic field direction exhibit anomalous scaling exponents, which indicates the existence of intermittent structures.

SU-E-J-200: Operation of An Electron Accelerator On An Integrated MR-Linac System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harasimowicz, J; Roberts, D; Shinton, I

2015-06-15

Purpose: An integrated MRI guided radiotherapy system poses a challenge of operating a linear accelerator in the presence of a magnetic field as the magnetic force acting on the electrons could Result in radiation source displacement and subsequent reduction of dose output. It was the purpose of this work to test the performance of a linac in the presence of a 1.5T MRI system. Methods: The first experimental MRI guided radiotherapy system at UMC-Utrecht consisting of an Elekta linac rotating around a 1.5T Magnex magnet was examined. A passive magnetic shield was simulated, designed and installed to reduce the influencemore » of the MRI magnet stray field on the electron beamline. The B field inside the shield was measured as a function of gantry angle and measurements of dose rate constancy upon gantry rotation were performed. Results: The magnitude of the magnetic field on the electron beam path without the shield was as high as 70G. It varied by up to 15G with gantry rotation due to the presence of metal beams in the bunker floor which resulted in dose output drop of up to 70% at certain gantry angles. With the prototype shield, field magnitude was reduced to well below 0.5G everywhere along the electron beam path. Field variation with gantry rotation was decreased to below 0.2G and enabled dose output of the linac to be recovered at all gantry angles. The homogeneity of the field inside the MRI magnet has not been compromised. Conclusion: It was demonstrated that the influence of the 1.5T magnet and the bunker design on the linac operation has been minimised. The performance will be further improved on the Elekta Atlantic system which incorporates a newly developed and optimised Philips magnet design and bunker construction. J Harasimowicz, D Roberts, I Shinton and S Sund are employed by Elekta Limited Crawley, H Wang and M Zhong are employed by Elekta Beijing Medical Systems Co. Ltd., J Overweg is employed by Philips Technologie GmbH Forschungslaboratorien.« less

Magnetic-cusp, cathodic-arc source

DOEpatents

Falabella, S.

1995-11-21

A magnetic-cusp for a cathodic-arc source wherein the arc is confined to the desired cathode surface, provides a current path for electrons from the cathode to the anode, and utilizes electric and magnetic fields to guide ions from the cathode to a point of use, such as substrates to be coated. The magnetic-cusp insures arc stability by an easy magnetic path from anode to cathode, while the straight-through arrangement leads to high ion transmission. 3 figs.

Charged particle motions in the distended magnetospheres of Jupiter and Saturn

NASA Technical Reports Server (NTRS)

Birmingham, T. J.

1982-01-01

Charged particle motion in the guiding center approximation is analyzed for models of the Jovian and Saturnian magnetospheric magnetic fields based on Voyager magnetometer observations. Field lines are traced and exhibit the distention which arises from azimuthally circulating magnetospheric currents. The spatial dependencies of the guiding center bounce period and azimuthal drift rate are investigated for the model fields. Non-dipolar effects in the gradient-curvature drift rate are most important at the equator and affect particles with all mirror latitudes. The effect is a factor of 10-15 for Jupiter with its strong magnetodisc current and 1-2 for Saturn with its more moderate ring current. Limits of adiabaticity, where particle gyroradii become comparable with magnetic scale lengths, are discussed and are shown to occur at quite modest kinetic energies for protons and heavier ions.

Experimental Demonstration of Magnetic Reconnection in a Laboratory Scale with Guide Field

NASA Astrophysics Data System (ADS)

Kim, Hyunsue; Egedal, Jan; Olsen, Joe; Endrizzi, Douglass; Wallace, John; TREX Team

2017-10-01

Through a process called magnetic reconnection, the opposing solar wind and Earth magnetic fields annihilate and allow energetic solar particles to enter the magnetosphere. This energetic plasma can cause major disturbances to satellite communication networks and navigation systems, as well as electrical power grids. To better understand this process and prevent significant economic losses, NASA has launched the MMS Mission in 2015, a cluster of spacecraft which directly probes the reconnection sites in the magnetosphere. Though in situ measurements of reconnection in space are essential to our understanding of the process, the mission comes at a cost of over 1 billion. Thus, smaller laboratory experiments become essential to compliment the data acquired by MMS at relatively low cost. The Terrestrial Reconnection Experiment (TREX) currently aims to probe a similar configuration to dayside reconnection by adding a toroidal guide magnetic field, where under the right conditions, high frequency turbulent fluctuations are expected. Using a set of fast Langmuir probes to diagnose the fluctuations, the global structure of the plasma turbulence can be reconstructed. In this poster, an overview of the upgraded experiment and design progress of the fast Lprobe will be provided. NSF/DOE award DE-SC0013032.

Bats Can Use Magnetic Compass in Foraging Behavior

NASA Astrophysics Data System (ADS)

Tian, L.; Zhang, B.; Pan, Y.; Zhu, R.

2016-12-01

Foraging plays an important role in an animal's ability to survive and reproduce. It is widely recognized that many animals and microorganisms can use geomagnetic compass in migration or homing orientation. Among them, bats, the only flying mammals, can use the magnetic compass in migrating orientations. For instance, we found the migratory microbat, Nyctalus plancyi, could use the magnetic polarity compass in roosting orientation under the strength range at least from a much weaker magnetic field than the present-day geomagnetic field (as low as 10 μT) to up to stronger magnetic field (100 μT). This high sensitivity to magnetic fields intensity may explain how magnetic orientation could have long-term evolved in bats even as the Earth's magnetic field strength varied as the polarity reversed many times in the past. Recently, we carried out foraging behavioral experiments on N. plancyi under various magnetic field conditions. Interestingly, it has shown that, although the auditory including echolocation, or olfactory sense may be the primary methods for seeking food under totally dark circumstance, the bats showed preferred foraging orientations at the magnetic north-south directions when any other sensory cues are insufficient for location of the food. It confirmed that bats could optimally use multiple directional cues including the geomagnetic field in their foraging in field. When bats foraging, they would navigate along the magnetic field direction if there were no direct sensory cues. As it gets close, the direct cues from food would guide them to the food.

Development of Multistep and Degenerate Variational Integrators for Applications in Plasma Physics

NASA Astrophysics Data System (ADS)

Ellison, Charles Leland

Geometric integrators yield high-fidelity numerical results by retaining conservation laws in the time advance. A particularly powerful class of geometric integrators is symplectic integrators, which are widely used in orbital mechanics and accelerator physics. An important application presently lacking symplectic integrators is the guiding center motion of magnetized particles represented by non-canonical coordinates. Because guiding center trajectories are foundational to many simulations of magnetically confined plasmas, geometric guiding center algorithms have high potential for impact. The motivation is compounded by the need to simulate long-pulse fusion devices, including ITER, and opportunities in high performance computing, including the use of petascale resources and beyond. This dissertation uses a systematic procedure for constructing geometric integrators --- known as variational integration --- to deliver new algorithms for guiding center trajectories and other plasma-relevant dynamical systems. These variational integrators are non-trivial because the Lagrangians of interest are degenerate - the Euler-Lagrange equations are first-order differential equations and the Legendre transform is not invertible. The first contribution of this dissertation is that variational integrators for degenerate Lagrangian systems are typically multistep methods. Multistep methods admit parasitic mode instabilities that can ruin the numerical results. These instabilities motivate the second major contribution: degenerate variational integrators. By replicating the degeneracy of the continuous system, degenerate variational integrators avoid parasitic mode instabilities. The new methods are therefore robust geometric integrators for degenerate Lagrangian systems. These developments in variational integration theory culminate in one-step degenerate variational integrators for non-canonical magnetic field line flow and guiding center dynamics. The guiding center integrator assumes coordinates such that one component of the magnetic field is zero; it is shown how to construct such coordinates for nested magnetic surface configurations. Additionally, collisional drag effects are incorporated in the variational guiding center algorithm for the first time, allowing simulation of energetic particle thermalization. Advantages relative to existing canonical-symplectic and non-geometric algorithms are numerically demonstrated. All algorithms have been implemented as part of a modern, parallel, ODE-solving library, suitable for use in high-performance simulations.

Particle Dynamics at and near the Electron and Ion Diffusion Regions as a Function of Guide Field

NASA Astrophysics Data System (ADS)

Giles, Barbara; Burch, James; Phan, Tai; Webster, James; Avanov, Levon; Torbert, Roy; Chen, Li-Jen; Chandler, Michael; Dorelli, John; Ergun, Robert; Fuselier, Stephen; Gershman, Daniel; Lavraud, Benoit; Moore, Thomas; Paterson, William; Pollock, Craig; Russell, Christopher; Saito, Yoshifumi; Strangeway, Robert; Wang, Shan

2017-04-01

At the dayside magnetopause, magnetic reconnection often occurs in thin sheets of plasma carrying electrical currents and rotating magnetic fields. Charged particles interact strongly with the magnetic field and simultaneously their motions modify the fields. Researchers are able to simulate the macroscopic interactions between the two plasma domains on both sides of the magnetopause and, for precise results, include individual particle motions to better describe the microscopic scales. Here, observed ion and electron distributions are compared for asymmetric reconnection events with weak-, moderate-, and strong-guide fields. Several of the structures noted have been demonstrated in simulations and others have not been predicted or explained to date. We report on these observations and their persistence. In particular, we highlight counterstreaming low-energy ion distributions that are seen to persist regardless of increasing guide-field. Distributions of this type were first published by Burch and Phan [GRL, 2016] for an 8 Dec 2015 event and by Wang et al. [GRL, 2016] for a 16 Oct 2015 event. Wang et al. showed the distributions were produced by the reflection of magnetosheath ions by the normal electric field at the magnetopause. This report presents further results on the relationship between the counterstreaming ions with electron distributions, which show the ions traversing the magnetosheath, X-line, and in one case the electron stagnation point. We suggest the counterstreaming ions become the source of D-shaped distributions at points where the field line opening is indicated by the electron distributions. In addition, we suggest they become the source of ion crescent distributions that result from acceleration of ions by the reconnection electric field. Burch, J. L., and T. D. Phan (2016), Magnetic reconnection at the dayside magnetopause: Advances with MMS, Geophys. Res. Lett., 43, 8327-8338, doi:10.1002/2016GL069787. Wang, S., et al. (2016), Two-scale ion meandering caused by the polarization electric field during asymmetric reconnection, Geophys. Res. Lett., 43, 7831-7839, doi:10.1002/2016GL069842.

Magnetically-guided assembly of microfluidic fibers for ordered construction of diverse netlike modules

NASA Astrophysics Data System (ADS)

Li, Xingfu; Shi, Qing; Wang, Huaping; Sun, Tao; Huang, Qiang; Fukuda, Toshio

2017-12-01

In this paper, a magnetically-guided assembly method is proposed to methodically construct diverse modules with a microfiber-based network for promoting nutrient circulation and waste excretion of cell culture. The microfiber is smoothly spun from the microfluidic device via precise control of the volumetric flow rate, and superparamagnetic nanoparticles within the alginate solution of the microfluidic fiber enable its magnetic response. The magnetized device is used to effectively capture the microfiber using its powerful magnetic flux density and high magnetic field gradient. Subsequently, the dot-matrix magnetic flux density is used to distribute the microfibers in an orderly fashion that depends on the array structure of the magnetized device. Furthermore, the magnetic microfluidic fibers are spatially organized into desired locations and are cross-aligned to form highly interconnected netlike modules in a liquid environment. Therefore, the experimental results herein demonstrate the structural controllability and stability of various modules and establish the effectiveness of the proposed method.

Safety of High Speed Guided Ground Transportation Systems : Comparison of Magnetic and Electric Fields of Conventional and Advanced Electrified Transportation Systems

DOT National Transportation Integrated Search

1993-08-01

The safety of magnetically levitated (maglev) and high speed rail (HSR) passenger trains proposed for application in the United States is the responsibility of the Federal Railroad Administration (FRA). Plans for near future US applications include m...

Safety of High Speed Guided Ground Transportation Systems : Magnetic and Electric Field Testing of the Massachusetts Bay Transportation ... v. 2. Appendix

DOT National Transportation Integrated Search

1993-06-01

The safety of magnetically levitated (maglev) and high speed rail (HSR) trains proposed for application in the United States is the responsibility of the Federal Railroad Administration (FRA). Plans for near future US applications include maglev proj...

Domain-wall guided nucleation of superconductivity in hybrid ferromagnet-superconductor-ferromagnet layered structures.

PubMed

Gillijns, W; Aladyshkin, A Yu; Lange, M; Van Bael, M J; Moshchalkov, V V

2005-11-25

Domain-wall superconductivity is studied in a superconducting Nb film placed between two ferromagnetic Co/Pd multilayers with perpendicular magnetization. The parameters of top and bottom ferromagnetic films are chosen to provide different coercive fields, so that the magnetic domain structure of the ferromagnets can be selectively controlled. From the dependence of the critical temperature Tc on the applied magnetic field H, we have found evidence for domain-wall superconductivity in this three-layered F/S/F structure for different magnetic domain patterns. The phase boundary, calculated numerically for this structure from the linearized Ginzburg-Landau equation, is in good agreement with the experimental data.

Ultra-sensitive magnetic microscopy with an optically pumped magnetometer

DOE PAGES

Kim, Young Jin; Savukov, Igor Mykhaylovich

2016-04-22

Optically pumped magnetometers (OPMs) based on lasers and alkali-metal vapor cells are currently the most sensitive non-cryogenic magnetic field sensors. Many applications in neuroscience and other fields require high-resolution, high-sensitivity magnetic microscopic measurements. In order to meet this demand we combined a cm-size spin-exchange relaxation-free (SERF) OPM and flux guides (FGs) to realize an ultra-sensitive FG-OPM magnetic microscope. The FGs serve to transmit the target magnetic flux to the OPM thus improving both the resolution and sensitivity to small magnetic objects. We investigated the performance of the FG-OPM device using experimental and numerical methods, and demonstrated that an optimized devicemore » can achieve a unique combination of high resolution (80 μm) and high sensitivity (8.1 pT/). Additionally, we also performed numerical calculations of the magnetic field distribution in the FGs to estimate the magnetic noise originating from the domain fluctuations in the material of the FGs. We anticipate many applications of the FG-OPM device such as the detection of micro-biological magnetic fields; the detection of magnetic nano-particles; and non-destructive testing. From our theoretical estimate, an FG-OPM could detect the magnetic field of a single neuron, which would be an important milestone in neuroscience.« less

Ultra-sensitive Magnetic Microscopy with an Optically Pumped Magnetometer

NASA Astrophysics Data System (ADS)

Kim, Young Jin; Savukov, Igor

2016-04-01

Optically pumped magnetometers (OPMs) based on lasers and alkali-metal vapor cells are currently the most sensitive non-cryogenic magnetic field sensors. Many applications in neuroscience and other fields require high-resolution, high-sensitivity magnetic microscopic measurements. In order to meet this demand we combined a cm-size spin-exchange relaxation-free (SERF) OPM and flux guides (FGs) to realize an ultra-sensitive FG-OPM magnetic microscope. The FGs serve to transmit the target magnetic flux to the OPM thus improving both the resolution and sensitivity to small magnetic objects. We investigated the performance of the FG-OPM device using experimental and numerical methods, and demonstrated that an optimized device can achieve a unique combination of high resolution (80 μm) and high sensitivity (8.1 pT/). In addition, we also performed numerical calculations of the magnetic field distribution in the FGs to estimate the magnetic noise originating from the domain fluctuations in the material of the FGs. We anticipate many applications of the FG-OPM device such as the detection of micro-biological magnetic fields; the detection of magnetic nano-particles; and non-destructive testing. From our theoretical estimate, an FG-OPM could detect the magnetic field of a single neuron, which would be an important milestone in neuroscience.

Ultra-sensitive magnetic microscopy with an optically pumped magnetometer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Young Jin; Savukov, Igor Mykhaylovich

Optically pumped magnetometers (OPMs) based on lasers and alkali-metal vapor cells are currently the most sensitive non-cryogenic magnetic field sensors. Many applications in neuroscience and other fields require high-resolution, high-sensitivity magnetic microscopic measurements. In order to meet this demand we combined a cm-size spin-exchange relaxation-free (SERF) OPM and flux guides (FGs) to realize an ultra-sensitive FG-OPM magnetic microscope. The FGs serve to transmit the target magnetic flux to the OPM thus improving both the resolution and sensitivity to small magnetic objects. We investigated the performance of the FG-OPM device using experimental and numerical methods, and demonstrated that an optimized devicemore » can achieve a unique combination of high resolution (80 μm) and high sensitivity (8.1 pT/). Additionally, we also performed numerical calculations of the magnetic field distribution in the FGs to estimate the magnetic noise originating from the domain fluctuations in the material of the FGs. We anticipate many applications of the FG-OPM device such as the detection of micro-biological magnetic fields; the detection of magnetic nano-particles; and non-destructive testing. From our theoretical estimate, an FG-OPM could detect the magnetic field of a single neuron, which would be an important milestone in neuroscience.« less

Full-field drift Hamiltonian particle orbits in 3D geometry

NASA Astrophysics Data System (ADS)

Cooper, W. A.; Graves, J. P.; Brunner, S.; Isaev, M. Yu

2011-02-01

A Hamiltonian/Lagrangian theory to describe guiding centre orbit drift motion which is canonical in the Boozer coordinate frame has been extended to include full electromagnetic perturbed fields in anisotropic pressure 3D equilibria with nested magnetic flux surfaces. A redefinition of the guiding centre velocity to eliminate the motion due to finite equilibrium radial magnetic fields and the choice of a gauge condition that sets the radial component of the electromagnetic vector potential to zero are invoked to guarantee that the Boozer angular coordinates retain the canonical structure. The canonical momenta are identified and the guiding centre particle radial drift motion and parallel gyroradius evolution are derived. The particle coordinate position is linearly modified by wave-particle interactions. All the nonlinear wave-wave interactions appear explicitly only in the evolution of the parallel gyroradius. The radial variation of the electrostatic potential is related to the binormal component of the displacement vector for MHD-type perturbations. The electromagnetic vector potential projections can then be determined from the electrostatic potential and the radial component of the MHD displacement vector.

Magnetic Eigenmodes in the Madison Dynamo Experiment

NASA Astrophysics Data System (ADS)

Nornberg, M. D.; Bayliss, R. A.; Forest, C. B.; Kendrick, R. D.; O'Connell, R.; Spence, E. J.

2002-11-01

A spherical dynamo experiment has been constructed at the University of Wisconsin's liquid sodium facility. The goals of the experiment are to observe and understand magnetic instabilities driven by flow shear in MHD systems, investigate MHD turbulence for magnetic Reynolds numbers of 100, and understand the role of fluid turbulence in current generation. Magnetic field generation is only possible for specific flow geometries. We have studied and achieved simple roll flow geometries in a full scale water experiment. Results from the water experiment have guided the design of the sodium experiment. The experiment consists of a 1 m diameter, spherical stainless steel vessel filled with liquid sodium at 110 Celsius. Two 100 Hp motors with impellers drive flows in the liquid sodium with flow velocities of 15 m/s. A gaussian grid of 66 Hall probes on the surface of the sodium vessel measure the generated external magnetic field. Hall probe feed-thru arrays measure the internal field. A pair of magnetic field coils produce a roughly uniform field inside the sphere with a centerline field strength of 100 gauss. Preliminary investigations include measurements of the turbulent electromotive force and excitation of magnetic eigenmodes.

Electron energization mechanisms in collisionless magnetic reconnection for different guide-field intensities

NASA Astrophysics Data System (ADS)

Pucci, F.; Usami, S.; Guo, X.; Ji, H.; Horiuchi, R.; Okamura, S.

2017-12-01

Electron dynamics and energization are a key component of magnetic field dissipation in collisionless reconnection. Indeed, in 2D reconnection, the main mechanism that limits the current density and provides the resistivity most probably relies on the electron pressure tensor term which has been shown to break the frozen-in condition at the x-point (Ishizawa and Horiuchi 2005; Horiuchi et al. 2014). In addition the electron-meandering-orbit scale controls the width of the electron dissipation region around the x-point, where the electron temperature is observed to increase, so understanding the electron heating mechanism is fundamental for magnetic reconnection. It has been shown by Guo et al. 2017 that for a 2D high guide field configuration (Bz/B0 = 3) electron perpendicular heating is mainly due to the breaking of magnetic moment conservation in the separatrix region while electron perpendicular acceleration takes place mainly in the downstream near the X-point. Electron velocity distributions have been shown to exhibit highly structured features within a few electron skin depths from the X line (Bessho et al. 2014) as well as in the exhaust (Shuster et al. 2014). By means of two-dimensional, full-particle simulations in an open system (Pei et al. 2001; Ohtani and R. Horiuchi 2009), we investigate how the energization mechanism depends on the guide field intensity. We compare electron distribution functions as well as particles orbits, in the electron diffusion region and the exhaust, in order to clarify the preferential electron heating/acceleration in two-dimensional systems. We will then compare our results with observations using the present catalogue of MMS diffusion region crossings.

Guiding and focusing of fast electron beams produced by ultra-intense laser pulse using a double cone funnel target

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Wen-shuai; Cai, Hong-bo, E-mail: Cai-hongbo@iapcm.ac.cn; HEDPS, Center for Applied Physics and Technology, Peking University, Beijing 100871

A novel double cone funnel target design aiming at efficiently guiding and focusing fast electron beams produced in high intensity (>10{sup 19 }W/cm{sup 2}) laser-solid interactions is investigated via two-dimensional particle-in-cell simulations. The forward-going fast electron beams are shown to be directed and focused to a smaller size in comparison with the incident laser spot size. This plasma funnel attached on the cone target guides and focuses electrons in a manner akin to the control of liquid by a plastic funnel. Such device has the potential to add substantial design flexibility and prevent inefficiencies for important applications such as fast ignition.more » Two reasons account for the collimation of fast electron beams. First, the sheath electric fields and quasistatic magnetic fields inside the vacuum gap of the double cone provide confinement of the fast electrons in the laser-plasma interaction region. Second, the interface magnetic fields inside the beam collimator further guide and focus the fast electrons during the transport. The application of this technique to cone-guided fast ignition is considered, and it is shown that it can enhance the laser energy deposition in the compressed fuel plasma by a factor of 2 in comparison with the single cone target case.« less

Magnetic Particle / Magnetic Resonance Imaging: In-Vitro MPI-Guided Real Time Catheter Tracking and 4D Angioplasty Using a Road Map and Blood Pool Tracer Approach.

PubMed

Salamon, Johannes; Hofmann, Martin; Jung, Caroline; Kaul, Michael Gerhard; Werner, Franziska; Them, Kolja; Reimer, Rudolph; Nielsen, Peter; Vom Scheidt, Annika; Adam, Gerhard; Knopp, Tobias; Ittrich, Harald

2016-01-01

In-vitro evaluation of the feasibility of 4D real time tracking of endovascular devices and stenosis treatment with a magnetic particle imaging (MPI) / magnetic resonance imaging (MRI) road map approach and an MPI-guided approach using a blood pool tracer. A guide wire and angioplasty-catheter were labeled with a thin layer of magnetic lacquer. For real time MPI a custom made software framework was developed. A stenotic vessel phantom filled with saline or superparamagnetic iron oxide nanoparticles (MM4) was equipped with bimodal fiducial markers for co-registration in preclinical 7T MRI and MPI. In-vitro angioplasty was performed inflating the balloon with saline or MM4. MPI data were acquired using a field of view of 37.3×37.3×18.6 mm3 and a frame rate of 46 volumes/sec. Analysis of the magnetic lacquer-marks on the devices were performed with electron microscopy, atomic absorption spectrometry and micro-computed tomography. Magnetic marks allowed for MPI/MRI guidance of interventional devices. Bimodal fiducial markers enable MPI/MRI image fusion for MRI based roadmapping. MRI roadmapping and the blood pool tracer approach facilitate MPI real time monitoring of in-vitro angioplasty. Successful angioplasty was verified with MPI and MRI. Magnetic marks consist of micrometer sized ferromagnetic plates mainly composed of iron and iron oxide. 4D real time MP imaging, tracking and guiding of endovascular instruments and in-vitro angioplasty is feasible. In addition to an approach that requires a blood pool tracer, MRI based roadmapping might emerge as a promising tool for radiation free 4D MPI-guided interventions.

Vertical Si nanowire arrays fabricated by magnetically guided metal-assisted chemical etching

NASA Astrophysics Data System (ADS)

Chun, Dong Won; Kim, Tae Kyoung; Choi, Duyoung; Caldwell, Elizabeth; Kim, Young Jin; Paik, Jae Cheol; Jin, Sungho; Chen, Renkun

2016-11-01

In this work, vertically aligned Si nanowire arrays were fabricated by magnetically guided metal-assisted directional chemical etching. Using an anodized aluminum oxide template as a shadow mask, nanoscale Ni dot arrays were fabricated on an Si wafer to serve as a mask to protect the Si during the etching. For the magnetically guided chemical etching, we deposited a tri-layer metal catalyst (Au/Fe/Au) in a Swiss-cheese configuration and etched the sample under the magnetic field to improve the directionality of the Si nanowire etching and increase the etching rate along the vertical direction. After the etching, the nanowires were dried with minimal surface-tension-induced aggregation by utilizing a supercritical CO2 drying procedure. High-resolution transmission electron microscopy (HR-TEM) analysis confirmed the formation of single-crystal Si nanowires. The method developed here for producing vertically aligned Si nanowire arrays could find a wide range of applications in electrochemical and electronic devices.

Development of a sub-cm high resolution ion Doppler tomography diagnostics for fine structure measurement of guide field reconnection in TS-U

NASA Astrophysics Data System (ADS)

Tanabe, Hiroshi; Koike, Hideya; Hatano, Hironori; Hayashi, Takumi; Cao, Qinghong; Himeno, Shunichi; Kaneda, Taishi; Akimitsu, Moe; Sawada, Asuka; Ono, Yasushi

2017-10-01

A new type of high-throughput/high-resolution 96CH ion Doppler tomography diagnostics has been developed using ``multi-slit'' spectroscopy technique for detailed investigation of fine structure formation during high guide field magnetic reconnection. In the last three years, high field merging experiment in MAST pioneered new frontiers of reconnection heating: formation of highly peaked structure around X-point in high guide field condition (Bt > 0.3 T), outflow dissipation under the influence of better plasma confinement to form high temperature ring structure which aligns with closed flux surface of toroidal plasma, and interaction between ion and electron temperature profile during transport/confinement phase to form triple peak structure (τeiE 4 ms). To investigate more detailed mechanism with in-situ magnetic measurement, the university of Tokyo starts the upgrade of plasma parameters and spatial resolution of optical diagnostics as in MAST. Now, a new type of high-throughput/high-resolution 96CH ion Doppler tomography diagnostics system construction has been completed and it successfully resolved fine structure of ion heating downstream, aligned with closed flux surface formed by reconnected field. This work was supported by JSPS KAKENHI Grant Numbers 15H05750, 15K14279 and 17H04863.

Trajectories of charged particles in radial electric and uniform axial magnetic fields

NASA Technical Reports Server (NTRS)

Englert, G. W.

1979-01-01

Trajectories of charged particles were determined over a wide range of parameters characterizing motion in cylindrical low-pressure gas discharges and plasma heating devices which have steady radial electric fields perpendicular to uniform steady magnetic fields. Consideration was given to radial distributions characteristic of fields measured in a modified Penning discharge, in two NASA Lewis burnout-type plasma heating devices, and that estimated for the Ixion device. Numerical calculations of trajectories for such devices showed that differences between cyclotron frequency and qB/m and between azimuthal drift and a guiding center approximation are appreciable.

Studies of nonlinear interactions between counter-propagating Alfv'en waves in the LAPD

NASA Astrophysics Data System (ADS)

Auerbach, D. W.; Perez, J. C.; Carter, T. A.; Boldyrev, S.

2007-11-01

From a weak turbulence point of view, nonlinear interactions between shear Alfv'en waves are fundamental to the energy cascade in low-frequency magnetic turbulence. We report here on an experimental study of counter-propagating Alfv'en wave interactions in the Large Plasma Device (LAPD) at UCLA. Colliding, orthogonally polarized kinetic Alfv'en waves are generated by two antennae, separated by 5m along the guide magnetic field. Magnetic field and langmuir probes record plasma behavior between the antennae. When each antenna is operated separately, linearly polarized Alfv'en waves propagate in opposite directions along the guide field. When two antennae simultaneously excite counter propagating waves, we observe multiple side bands in the frequency domain, whose amplitude scales quadratically with wave amplitude. In the spatial domain we observe non-linear superposition in the 2D structure of the waves and spectral broadening in the perpendicular wave-number spectrum. This indicates the presence of nonlinear interaction of the counter propagating Alfv'en waves, and opens the possiblity to investigate Alfv'enic plasma turbulence in controlled and reproducible laboratory experiments.

Palm-size miniature superconducting bulk magnet

NASA Astrophysics Data System (ADS)

Saho, Norihide; Matsuda, Kazuya; Nishijima, Noriyo

The development of a small, light, powerful and energy-efficient superconducting magnet has been desired in order to realize better efficiency and manipulability in guiding magnetic nano-particles, magnetic organic cells and other items to the right place. This study focuses on the development of a high-temperature superconducting (HTS) bulk magnet characterized by comparatively low leak magnetism despite a relatively high magnetic field. On this basis, the authors developed a palm-sized superconducting bulk magnet, which is the world's smallest, lightest, and lowest power consuming, as well as a new technology to effectively magnetize such a bulk magnet in a compact Stirling-cycle cryocooler (magnet C) with a pre-magnetized HTS bulk magnet (magnet B) in a compact cryocooler. This technology is demonstrated in two steps. In the first step, magnet B is magnetized using a superconducting solenoid magnet with a high magnetic field (magnet A) via the field cooling method. In the second step, magnet C is magnetized in the high magnetic field of magnet B. The prototype magnet C weighs 1.8 kg, and measures 235 × 65 × 115 mm (L × W × H). Magnet B was magnetized to 4.9 T using a 5 T magnet, and the target, magnet C, was magnetized using magnet B so that its maximum trapped magnetic flux density reached the value of 3.15 T. The net power consumption in a steady cooling state was 23 W, which is very low and comparable to that of a laptop computer.

Hybrid simulations of radial transport driven by the Rayleigh-Taylor instability

NASA Astrophysics Data System (ADS)

Delamere, P. A.; Stauffer, B. H.; Ma, X.

2017-12-01

Plasma transport in the rapidly rotating giant magnetospheres is thought to involve a centrifugally-driven flux tube interchange instability, similar to the Rayleigh-Taylor (RT) instability. In three dimensions, the convective flow patterns associated with the RT instability can produce strong guide field reconnection, allowing plasma mass to move radially outward while conserving magnetic flux (Ma et al., 2016). We present a set of hybrid (kinetic ion / fluid electron) plasma simulations of the RT instability using high plasma beta conditions appropriate for Jupiter's inner and middle magnetosphere. A density gradient, combined with a centrifugal force, provide appropriate RT onset conditions. Pressure balance is achieved by initializing two ion populations: one with fixed temperature, but varying density, and the other with fixed density, but a temperature gradient that offsets the density gradient from the first population and the centrifugal force (effective gravity). We first analyze two-dimensional results for the plane perpendicular to the magnetic field by comparing growth rates as a function of wave vector following Huba et al. (1998). Prescribed perpendicular wave modes are seeded with an initial velocity perturbation. We then extend the model to three dimensions, introducing a stabilizing parallel wave vector. Boundary conditions in the parallel direction prohibit motion of the magnetic field line footprints to model the eigenmodes of the magnetodisc's resonant cavity. We again compare growth rates based on perpendicular wave number, but also on the parallel extent of the resonant cavity, which fixes the size of the largest parallel wavelength. Finally, we search for evidence of strong guide field magnetic reconnection within the domain by identifying areas with large parallel electric fields or changes in magnetic field topology.

University Physics, Study Guide, Revised Edition

NASA Astrophysics Data System (ADS)

Benson, Harris

1996-01-01

Partial table of contents: Vectors. One-Dimensional Kinematics. Particle Dynamics II. Work and Energy. Linear Momentum. Systems of Particles. Angular Momentum and Statics. Gravitation. Solids and Fluids. Oscillations. Mechanical Waves. Sound. First Law of Thermodynamics. Kinetic Theory. Entropy and the Second Law of Thermodynamics. Electrostatics. The Electric Field. Gauss's Law. Electric Potential. Current and Resistance. The Magnetic Field. Sources of the Magnetic Field. Electromagnetic Induction. Light: Reflection and Refraction. Lenses and Optical Instruments. Wave Optics I. Special Relativity. Early Quantum Theory. Nuclear Physics. Appendices. Answers to Odd-Numbered Exercises and Problems. Index.

Circulating Magnetic Microbubbles for Localized Real-Time Control of Drug Delivery by Ultrasonography-Guided Magnetic Targeting and Ultrasound

PubMed Central

Chertok, Beata; Langer, Robert

2018-01-01

Image-guided and target-selective modulation of drug delivery by external physical triggers at the site of pathology has the potential to enable tailored control of drug targeting. Magnetic microbubbles that are responsive to magnetic and acoustic modulation and visible to ultrasonography have been proposed as a means to realize this drug targeting strategy. To comply with this strategy in vivo, magnetic microbubbles must circulate systemically and evade deposition in pulmonary capillaries, while also preserving magnetic and acoustic activities in circulation over time. Unfortunately, challenges in fabricating magnetic microbubbles with such characteristics have limited progress in this field. In this report, we develop magnetic microbubbles (MagMB) that display strong magnetic and acoustic activities, while also preserving the ability to circulate systemically and evade pulmonary entrapment. Methods: We systematically evaluated the characteristics of MagMB including their pharmacokinetics, biodistribution, visibility to ultrasonography and amenability to magneto-acoustic modulation in tumor-bearing mice. We further assessed the applicability of MagMB for ultrasonography-guided control of drug targeting. Results: Following intravenous injection, MagMB exhibited a 17- to 90-fold lower pulmonary entrapment compared to previously reported magnetic microbubbles and mimicked circulation persistence of the clinically utilized Definity microbubbles (>10 min). In addition, MagMB could be accumulated in tumor vasculature by magnetic targeting, monitored by ultrasonography and collapsed by focused ultrasound on demand to activate drug deposition at the target. Furthermore, drug delivery to target tumors could be enhanced by adjusting the magneto-acoustic modulation based on ultrasonographic monitoring of MagMB in real-time. Conclusions: Circulating MagMB in conjunction with ultrasonography-guided magneto-acoustic modulation may provide a strategy for tailored minimally-invasive control over drug delivery to target tissues. PMID:29290812

Physics of the diffusion region in the Magnetospheric Multiscale era

NASA Astrophysics Data System (ADS)

Chen, L. J.; Hesse, M.; Wang, S.; Ergun, R.; Bessho, N.; Burch, J. L.; Giles, B. L.; Torbert, R. B.; Gershman, D. J.; Wilson, L. B., III; Dorelli, J.; Pollock, C. J.; Moore, T. E.; Lavraud, B.; Strangeway, R. J.; Russell, C. T.; Khotyaintsev, Y. V.; Le Contel, O.; Avanov, L. A.

2016-12-01

Encounters of reconnection diffusion regions by the Magnetospheric Multiscale (MMS) mission during its first magnetopause scan are studied in combination with theories and simulations. The goal is to understand by first-principles how stored magnetic energy is converted into plasma thermal and bulk flow energies via particle energization, mixing and interaction with waves. The magnetosheath population having much higher density than the magnetospheric plasma is an outstanding narrator for and participant in the magnetospheric part of the diffusion region. For reconnection with negligible guide fields, the accelerated magnetosheath population (for both electrons and ions) is cyclotron turned by the reconnected magnetic field to form outflow jets, and then gyrotropized downstream. Wave fluctuations are reduced in the central electron diffusion region (EDR) and do not dominate the energy conversion there. For an event with a significant guide field to magnetize the electrons, wave fluctuations at the lower hybrid frequency dominate the energy conversion in the EDR, and the fastest electron outflow is established dominantly by a strong perpendicular electric field via the ExB flow in one exhaust and by time-of-flight effects along with parallel electric field acceleration in the other. Whether the above features are common threads to magnetopause reconnection diffusion regions is a question to be further examined.

Magnetically enhanced adeno-associated viral vector delivery for human neural stem cell infection.

PubMed

Kim, Eunmi; Oh, Ji-Seon; Ahn, Ik-Sung; Park, Kook In; Jang, Jae-Hyung

2011-11-01

Gene therapy technology is a powerful tool to elucidate the molecular cues that precisely regulate stem cell fates, but developing safe vehicles or mechanisms that are capable of delivering genes to stem cells with high efficiency remains a challenge. In this study, we developed a magnetically guided adeno-associated virus (AAV) delivery system for gene delivery to human neural stem cells (hNSCs). Magnetically guided AAV delivery resulted in rapid accumulation of vectors on target cells followed by forced penetration of the vectors across the plasma membrane, ultimately leading to fast and efficient cellular transduction. To combine AAV vectors with the magnetically guided delivery, AAV was genetically modified to display hexa-histidine (6xHis) on the physically exposed loop of the AAV2 capsid (6xHis AAV), which interacted with nickel ions chelated on NTA-biotin conjugated to streptavidin-coated superparamagnetic iron oxide nanoparticles (NiStNPs). NiStNP-mediated 6xHis AAV delivery under magnetic fields led to significantly enhanced cellular transduction in a non-permissive cell type (i.e., hNSCs). In addition, this delivery method reduced the viral exposure times required to induce a high level of transduction by as much as to 2-10 min of hNSC infection, thus demonstrating the great potential of magnetically guided AAV delivery for numerous gene therapy and stem cell applications. Copyright © 2011 Elsevier Ltd. All rights reserved.

The magnetic map of hatchling loggerhead sea turtles.

PubMed

Lohmann, Kenneth J; Putman, Nathan F; Lohmann, Catherine M F

2012-04-01

Young loggerhead sea turtles (Caretta caretta) from eastern Florida, U.S.A., undertake a transoceanic migration in which they gradually circle the North Atlantic Ocean before returning to the North American coast. Hatchlings in the open sea are guided at least partly by a 'magnetic map' in which regional magnetic fields function as navigational markers and elicit changes in swimming direction at crucial locations along the migratory route. The magnetic map exists in turtles that have never migrated and thus appears to be inherited. Turtles derive both longitudinal and latitudinal information from the Earth's field, most likely by exploiting unique combinations of field inclination and intensity that occur in different geographic areas. Similar mechanisms may function in the migrations of diverse animals. Copyright © 2011 Elsevier Ltd. All rights reserved.

Wide Band Low Noise Love Wave Magnetic Field Sensor System.

PubMed

Kittmann, Anne; Durdaut, Phillip; Zabel, Sebastian; Reermann, Jens; Schmalz, Julius; Spetzler, Benjamin; Meyners, Dirk; Sun, Nian X; McCord, Jeffrey; Gerken, Martina; Schmidt, Gerhard; Höft, Michael; Knöchel, Reinhard; Faupel, Franz; Quandt, Eckhard

2018-01-10

We present a comprehensive study of a magnetic sensor system that benefits from a new technique to substantially increase the magnetoelastic coupling of surface acoustic waves (SAW). The device uses shear horizontal acoustic surface waves that are guided by a fused silica layer with an amorphous magnetostrictive FeCoSiB thin film on top. The velocity of these so-called Love waves follows the magnetoelastically-induced changes of the shear modulus according to the magnetic field present. The SAW sensor is operated in a delay line configuration at approximately 150 MHz and translates the magnetic field to a time delay and a related phase shift. The fundamentals of this sensor concept are motivated by magnetic and mechanical simulations. They are experimentally verified using customized low-noise readout electronics. With an extremely low magnetic noise level of ≈100 pT/[Formula: see text], a bandwidth of 50 kHz and a dynamic range of 120 dB, this magnetic field sensor system shows outstanding characteristics. A range of additional measures to further increase the sensitivity are investigated with simulations.

Effect of the solenoid in various conditions of the laser ion source at Brookhaven National Laboratory

NASA Astrophysics Data System (ADS)

Ikeda, S.; Kumaki, M.; Kanesue, T.; Okamura, M.

2016-02-01

In the laser ion source (LIS) at the Brookhaven National Laboratory (BNL), a solenoid is used to guide the laser ablation plasma and modulate the extracted beam current. Many types of ion species are guided. In some cases, the plasma plume is injected into the solenoid away from the solenoidal axis. To investigate the effects of the solenoid on the beam extracted from the plasma that has different properties, the beam current was measured in the setup of the LIS at the BNL. The beam current of Li, Al, Si, Fe, and Au increased when the magnetic field was applied. For most of the species the peak current and the total charge within a single beam pulse increased around 10 times with a magnetic field less than 100 G. In addition, for some species the rate of increase of the peak currents became smaller when the magnetic flux densities were larger than certain values depending on the species. In this case, the current waveforms were distorted. At the same magnetic field value, the field was more effective on lighter species than on heavier ones. When plasma was injected offset from the axis of the solenoid, peak current and total charge became half of those without offset. The experimental data are useful for the operation of the LIS at the BNL.

Effect of the solenoid in various conditions of the laser ion source at Brookhaven National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ikeda, S., E-mail: ikeda.s.ae@m.titech.ac.jp; Nishina Center for Accelerator-Based Science, RIKEN, Wako, Saitama 351-0108; Kumaki, M.

In the laser ion source (LIS) at the Brookhaven National Laboratory (BNL), a solenoid is used to guide the laser ablation plasma and modulate the extracted beam current. Many types of ion species are guided. In some cases, the plasma plume is injected into the solenoid away from the solenoidal axis. To investigate the effects of the solenoid on the beam extracted from the plasma that has different properties, the beam current was measured in the setup of the LIS at the BNL. The beam current of Li, Al, Si, Fe, and Au increased when the magnetic field was applied.more » For most of the species the peak current and the total charge within a single beam pulse increased around 10 times with a magnetic field less than 100 G. In addition, for some species the rate of increase of the peak currents became smaller when the magnetic flux densities were larger than certain values depending on the species. In this case, the current waveforms were distorted. At the same magnetic field value, the field was more effective on lighter species than on heavier ones. When plasma was injected offset from the axis of the solenoid, peak current and total charge became half of those without offset. The experimental data are useful for the operation of the LIS at the BNL.« less

Effect of the solenoid in various conditions of the laser ion source at Brookhaven National Laboratory.

PubMed

Ikeda, S; Kumaki, M; Kanesue, T; Okamura, M

2016-02-01

In the laser ion source (LIS) at the Brookhaven National Laboratory (BNL), a solenoid is used to guide the laser ablation plasma and modulate the extracted beam current. Many types of ion species are guided. In some cases, the plasma plume is injected into the solenoid away from the solenoidal axis. To investigate the effects of the solenoid on the beam extracted from the plasma that has different properties, the beam current was measured in the setup of the LIS at the BNL. The beam current of Li, Al, Si, Fe, and Au increased when the magnetic field was applied. For most of the species the peak current and the total charge within a single beam pulse increased around 10 times with a magnetic field less than 100 G. In addition, for some species the rate of increase of the peak currents became smaller when the magnetic flux densities were larger than certain values depending on the species. In this case, the current waveforms were distorted. At the same magnetic field value, the field was more effective on lighter species than on heavier ones. When plasma was injected offset from the axis of the solenoid, peak current and total charge became half of those without offset. The experimental data are useful for the operation of the LIS at the BNL.

Safety of High Speed Guided Ground Transportation Systems : Magnetic and Electric Field Testing of the Washington Metropolitan Area Transit Authority Metrorail System. v. 1. Analysis.

DOT National Transportation Integrated Search

1993-06-01

The safety of magnetically levitated (maglev) and high speed rail (HSR) trains proposed for application in the United States is the responsibility of the Federal Railroad Administration (FRA). Plans for near future US applications include maglev tech...

Kubo conductivity of a strongly magnetized two-dimensional plasma.

NASA Technical Reports Server (NTRS)

Montgomery, D.; Tappert, F.

1971-01-01

The Kubo formula is used to evaluate the bulk electrical conductivity of a two-dimensional guiding-center plasma in a strong dc magnetic field. The particles interact only electrostatically. An ?anomalous' electrical conductivity is derived for this system, which parallels a recent result of Taylor and McNamara for the coefficient of spatial diffusion.

Solar tomography adaptive optics.

PubMed

Ren, Deqing; Zhu, Yongtian; Zhang, Xi; Dou, Jiangpei; Zhao, Gang

2014-03-10

Conventional solar adaptive optics uses one deformable mirror (DM) and one guide star for wave-front sensing, which seriously limits high-resolution imaging over a large field of view (FOV). Recent progress toward multiconjugate adaptive optics indicates that atmosphere turbulence induced wave-front distortion at different altitudes can be reconstructed by using multiple guide stars. To maximize the performance over a large FOV, we propose a solar tomography adaptive optics (TAO) system that uses tomographic wave-front information and uses one DM. We show that by fully taking advantage of the knowledge of three-dimensional wave-front distribution, a classical solar adaptive optics with one DM can provide an extra performance gain for high-resolution imaging over a large FOV in the near infrared. The TAO will allow existing one-deformable-mirror solar adaptive optics to deliver better performance over a large FOV for high-resolution magnetic field investigation, where solar activities occur in a two-dimensional field up to 60'', and where the near infrared is superior to the visible in terms of magnetic field sensitivity.

Thermoablation of Malignant Kidney Tumors Using Magnetic Nanoparticles: An In Vivo Feasibility Study in a Rabbit Model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bruners, Philipp, E-mail: bruners@hia.rwth-aachen.d; Braunschweig, Till; Hodenius, Michael

2010-02-15

The objective of this study was to assess the technical feasibility of CT-guided magnetic thermoablation for the treatment of malignant kidney tumors in a VX2 tumor rabbit model. VX2 tumors were implanted into the kidneys of five rabbits and allowed to grow for 2 weeks. After preinterventional CT perfusion imaging, CT-guided injection of superparamagnetic iron oxide particles (300 {mu}l) was performed, followed by exposure of the animals to an alternating electromagnetic field for 15 min ({approx}0.32 kA/m). Then animals underwent CT perfusion imaging again. Afterward, animals were sacrificed and kidneys were dissected for macroscopic and histological evaluation. Changes in perfusionmore » before and after exposure to the alternating magnetic field were analyzed. In one animal no tumor growth could be detected so the animal was used for optimization of the ablation procedure including injection technique and peri-interventional cross-sectional imaging (CT, MRI). After image-guided intratumoral injection of ferrofluids, the depiction of nanoparticle distribution by CT correlated well with macroscopic evaluation of the dissected kidneys. MRI was limited due to severe susceptibility artefacts. Postinterventional CT perfusion imaging revealed a perfusion deficiency around the ferrofluid deposits. Histological workup showed different zones of thermal damage adjacent to the ferrofluid deposits. In conclusion, CT-guided magnetic thermoablation of malignant kidney tumors is technically feasible in an animal model and results in a perfusion deficiency indicating tumor necrosis as depicted by CT perfusion imaging and shown in histological evaluation.« less

Substorm variations in the magnitude of the magnetic field - AMPTE/CCE observations

NASA Technical Reports Server (NTRS)

Lopez, R. E.; Sibeck, D. G.; Lui, A. T. Y.; Takahashi, K.; Mcentire, R. W.

1988-01-01

Using energetic-particle data taken in the near-earth tail by the AMPTE/Charge Composition Explorer (CCE) satellite, 167 ion injection events, that were essentially dispersionless over a 25-285 keV energy range, were identified, and the variations in the total magnetic field strength over the course of these events were examined in order to determine the dependence of the magnetic field strength on dipole latitude. Results indicate that, during periods of substorm activity, the latitudinal position of the current sheet varied significantly within the 32-deg wedge centered on the dipole equator traversed by CCE. Results also suggest that, even in the near-earth magnetotail out to 8.8 R(E) (CCE apogee), the local field measurements are a better guide to the determination of satellite's position relative to the current shield during a substorm, than is the magnetic latitude.

Ultrasensitive Magnetic Field Sensing Based on Refractive-Index-Matched Coupling.

PubMed

Rao, Jie; Pu, Shengli; Yao, Tianjun; Su, Delong

2017-07-07

An ultrasensitive magnetic field sensor is proposed and investigated experimentally. The no-core fiber is fusion-spliced between two pieces of single-mode fibers and then immersed in magnetic fluid with an appropriate value of refractive index. Under the refractive-index-matched coupling condition, the guided mode becomes leaky and a coupling wavelength dip in the transmission spectrum of the structure is observed. The coupling wavelength dip is extremely sensitive to the ambient environment. The excellent sensitivity to the refractive index is measured to be 116.681 μm/RIU (refractive index unit) in the refractive index range of 1.45691-1.45926. For the as-fabricated sensors, the highest magnetic field sensing sensitivities of 6.33 and 1.83 nm/mT are achieved at low and high fields, respectively. The sensitivity is considerably enhanced compared with those of previously designed, similar structures.

Test of Shi et al. Method to Infer the Magnetic Reconnection Geometry from Spacecraft Data: MHD Simulation with Guide Field and Antiparallel Kinetic Simulation

NASA Technical Reports Server (NTRS)

Denton, R.; Sonnerup, B. U. O.; Swisdak, M.; Birn, J.; Drake, J. F.; Heese, M.

2012-01-01

When analyzing data from an array of spacecraft (such as Cluster or MMS) crossing a site of magnetic reconnection, it is desirable to be able to accurately determine the orientation of the reconnection site. If the reconnection is quasi-two dimensional, there are three key directions, the direction of maximum inhomogeneity (the direction across the reconnection site), the direction of the reconnecting component of the magnetic field, and the direction of rough invariance (the "out of plane" direction). Using simulated spacecraft observations of magnetic reconnection in the geomagnetic tail, we extend our previous tests of the direction-finding method developed by Shi et al. (2005) and the method to determine the structure velocity relative to the spacecraft Vstr. These methods require data from four proximate spacecraft. We add artificial noise and calibration errors to the simulation fields, and then use the perturbed gradient of the magnetic field B and perturbed time derivative dB/dt, as described by Denton et al. (2010). Three new simulations are examined: a weakly three-dimensional, i.e., quasi-two-dimensional, MHD simulation without a guide field, a quasi-two-dimensional MHD simulation with a guide field, and a two-dimensional full dynamics kinetic simulation with inherent noise so that the apparent minimum gradient was not exactly zero, even without added artificial errors. We also examined variations of the spacecraft trajectory for the kinetic simulation. The accuracy of the directions found varied depending on the simulation and spacecraft trajectory, but all the directions could be found within about 10 for all cases. Various aspects of the method were examined, including how to choose averaging intervals and the best intervals for determining the directions and velocity. For the kinetic simulation, we also investigated in detail how the errors in the inferred gradient directions from the unmodified Shi et al. method (using the unperturbed gradient) depended on the amplitude of the calibration errors. For an accuracy of 3 for the maximum gradient direction, the calibration errors could be as large as 3% of reconnection magnetic field, while for the same accuracy for the minimum gradient direction, the calibration errors could only be as large as 0.03% of the reconnection magnetic field. These results suggest that the maximum gradient direction can normally be determined by the unmodified Shi et al. method, while the modified method or some other method must be used to accurately determine the minimum gradient direction. The structure velocity was found with magnitude accurate to 2% and direction accurate to within 5%.

Sci-Sat AM: Radiation Dosimetry and Practical Therapy Solutions - 05: Not all geometries are equivalent for magnetic field Fano cavity tests

DOE Office of Scientific and Technical Information (OSTI.GOV)

Malkov, Victor N.; Rogers, David W.O.

The coupling of MRI and radiation treatment systems for the application of magnetic resonance guided radiation therapy necessitates a reliable magnetic field capable Monte Carlo (MC) code. In addition to the influence of the magnetic field on dose distributions, the question of proper calibration has arisen due to the several percent variation of ion chamber and solid state detector responses in magnetic fields when compared to the 0 T case (Reynolds et al., Med Phys, 2013). In the absence of a magnetic field, EGSnrc has been shown to pass the Fano cavity test (a rigorous benchmarking tool of MC codes)more » at the 0.1 % level (Kawrakow, Med.Phys, 2000), and similar results should be required of magnetic field capable MC algorithms. To properly test such developing MC codes, the Fano cavity theorem has been adapted to function in a magnetic field (Bouchard et al., PMB, 2015). In this work, the Fano cavity test is applied in a slab and ion-chamber-like geometries to test the transport options of an implemented magnetic field algorithm in EGSnrc. Results show that the deviation of the MC dose from the expected Fano cavity theory value is highly sensitive to the choice of geometry, and the ion chamber geometry appears to pass the test more easily than larger slab geometries. As magnetic field MC codes begin to be used for dose simulations and correction factor calculations, care must be taken to apply the most rigorous Fano test geometries to ensure reliability of such algorithms.« less

Visualizing domain wall and reverse domain superconductivity.

PubMed

Iavarone, M; Moore, S A; Fedor, J; Ciocys, S T; Karapetrov, G; Pearson, J; Novosad, V; Bader, S D

2014-08-28

In magnetically coupled, planar ferromagnet-superconductor (F/S) hybrid structures, magnetic domain walls can be used to spatially confine the superconductivity. In contrast to a superconductor in a uniform applied magnetic field, the nucleation of the superconducting order parameter in F/S structures is governed by the inhomogeneous magnetic field distribution. The interplay between the superconductivity localized at the domain walls and far from the walls leads to effects such as re-entrant superconductivity and reverse domain superconductivity with the critical temperature depending upon the location. Here we use scanning tunnelling spectroscopy to directly image the nucleation of superconductivity at the domain wall in F/S structures realized with Co-Pd multilayers and Pb thin films. Our results demonstrate that such F/S structures are attractive model systems that offer the possibility to control the strength and the location of the superconducting nucleus by applying an external magnetic field, potentially useful to guide vortices for computing application.

Visualizing domain wall and reverse domain superconductivity

PubMed Central

Iavarone, M.; Moore, S. A.; Fedor, J.; Ciocys, S. T.; Karapetrov, G.; Pearson, J.; Novosad, V.; Bader, S. D.

2014-01-01

In magnetically coupled, planar ferromagnet-superconductor (F/S) hybrid structures, magnetic domain walls can be used to spatially confine the superconductivity. In contrast to a superconductor in a uniform applied magnetic field, the nucleation of the superconducting order parameter in F/S structures is governed by the inhomogeneous magnetic field distribution. The interplay between the superconductivity localized at the domain walls and far from the walls leads to effects such as re-entrant superconductivity and reverse domain superconductivity with the critical temperature depending upon the location. Here we use scanning tunnelling spectroscopy to directly image the nucleation of superconductivity at the domain wall in F/S structures realized with Co-Pd multilayers and Pb thin films. Our results demonstrate that such F/S structures are attractive model systems that offer the possibility to control the strength and the location of the superconducting nucleus by applying an external magnetic field, potentially useful to guide vortices for computing application. PMID:25164004

Guiding of relativistic electron beams in solid targets by resistively controlled magnetic fields.

PubMed

Kar, S; Robinson, A P L; Carroll, D C; Lundh, O; Markey, K; McKenna, P; Norreys, P; Zepf, M

2009-02-06

Guided transport of a relativistic electron beam in solid is achieved experimentally by exploiting the strong magnetic fields created at the interface of two metals of different electrical resistivities. This is of substantial relevance to the Fast Ignitor approach to fusion energy production [M. Tabak, Phys. Plasmas 12, 057305 (2005)10.1063/1.1871246], since it allows the electron deposition to be spatially tailored-thus adding substantial design flexibility and preventing inefficiencies due to electron beam spreading. In the experiment, optical transition radiation and thermal emission from the target rear surface provide a clear signature of the electron confinement within a high resistivity tin layer sandwiched transversely between two low resistivity aluminum slabs. The experimental data are found to agree well with numerical simulations.

RELATIVISTIC ELECTRONS PRODUCED BY RECONNECTING ELECTRIC FIELDS IN A LASER-DRIVEN BENCH-TOP SOLAR FLARE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhong, J. Y.; Zhang, K.; Yuan, D. W.

2016-08-01

Laboratory experiments have been carried out to model the magnetic reconnection process in a solar flare with powerful lasers. Relativistic electrons with energy up to megaelectronvolts are detected along the magnetic separatrices bounding the reconnection outflow, which exhibit a kappa-like distribution with an effective temperature of ∼10{sup 9} K. The acceleration of non-thermal electrons is found to be more efficient in the case with a guide magnetic field (a component of a magnetic field along the reconnection-induced electric field) than in the case without a guide field. Hardening of the spectrum at energies ≥500 keV is observed in both cases, which remarkably resembles themore » hardening of hard X-ray and γ -ray spectra observed in many solar flares. This supports a recent proposal that the hardening in the hard X-ray and γ -ray emissions of solar flares is due to a hardening of the source-electron spectrum. We also performed numerical simulations that help examine behaviors of electrons in the reconnection process with the electromagnetic field configurations occurring in the experiments. The trajectories of non-thermal electrons observed in the experiments were well duplicated in the simulations. Our numerical simulations generally reproduce the electron energy spectrum as well, except for the hardening of the electron spectrum. This suggests that other mechanisms such as shock or turbulence may play an important role in the production of the observed energetic electrons.« less

Explaining TeV cosmic-ray anisotropies with non-diffusive cosmic-ray propagation

DOE PAGES

Harding, James Patrick; Fryer, Chris Lee; Mendel, Susan Marie

2016-05-11

Constraining the behavior of cosmic ray data observed at Earth requires a precise understanding of how the cosmic rays propagate in the interstellar medium. The interstellar medium is not homogeneous; although turbulent magnetic fields dominate over large scales, small coherent regions of magnetic field exist on scales relevant to particle propagation in the nearby Galaxy. Guided propagation through a coherent field is significantly different from random particle diffusion and could be the explanation of spatial anisotropies in the observed cosmic rays. We present a Monte Carlo code to propagate cosmic particle through realistic magnetic field structures. We discuss the detailsmore » of the model as well as some preliminary studies which indicate that coherent magnetic structures are important effects in local cosmic-ray propagation, increasing the flux of cosmic rays by over two orders of magnitude at anisotropic locations on the sky. Furthermore, the features induced by coherent magnetic structure could be the cause of the observed TeV cosmic-ray anisotropy.« less

EXPLAINING TEV COSMIC-RAY ANISOTROPIES WITH NON-DIFFUSIVE COSMIC-RAY PROPAGATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harding, J. Patrick; Fryer, Chris L.; Mendel, Susan, E-mail: jpharding@lanl.gov, E-mail: fryer@lanl.gov, E-mail: smendel@lanl.gov

2016-05-10

Constraining the behavior of cosmic ray data observed at Earth requires a precise understanding of how the cosmic rays propagate in the interstellar medium. The interstellar medium is not homogeneous; although turbulent magnetic fields dominate over large scales, small coherent regions of magnetic field exist on scales relevant to particle propagation in the nearby Galaxy. Guided propagation through a coherent field is significantly different from random particle diffusion and could be the explanation of spatial anisotropies in the observed cosmic rays. We present a Monte Carlo code to propagate cosmic particle through realistic magnetic field structures. We discuss the detailsmore » of the model as well as some preliminary studies which indicate that coherent magnetic structures are important effects in local cosmic-ray propagation, increasing the flux of cosmic rays by over two orders of magnitude at anisotropic locations on the sky. The features induced by coherent magnetic structure could be the cause of the observed TeV cosmic-ray anisotropy.« less

Electromagnetic dissipation during asymmetric reconnection with a moderate guide field

NASA Astrophysics Data System (ADS)

Genestreti, Kevin; Burch, James; Cassak, Paul; Torbert, Roy; Phan, Tai; Ergun, Robert; Giles, Barbara; Russell, Chris; Wang, Shan; Akhavan-Tafti, Mojtaba; Varsani, Ali

2017-04-01

We calculate the work done on the plasma by the electromagnetic (EM) field, ⃗Jṡ⃗E', and analyze the related electron currents and electric fields, focusing on a single asymmetric guide field electron diffusion region (EDR) event observed by MMS on 8 December 2015. For this event, each of the four MMS spacecraft observed dissipation of EM energy at the in-plane magnetic null point, though large-scale generation/dissipation was observed inconsistently on the magnetospheric side of the boundary. The current at the null was carried by a beam-like population of magnetosheath electrons traveling anti-parallel to the guide field, whereas the current on the Earthward side of the boundary was carried by crescent-shaped electron distributions. We also analyze the terms in Ohm's law, finding a large residual electric field throughout the EDR, inertial and pressure divergence fields at the null, and pressure divergence fields at the magnetosphere-side EDR. Our analysis of the terms in Ohm's law suggests that the EDR had significant three-dimensional structure.

Guided self-assembly of magnetic beads for biomedical applications

NASA Astrophysics Data System (ADS)

Gusenbauer, Markus; Nguyen, Ha; Reichel, Franz; Exl, Lukas; Bance, Simon; Fischbacher, Johann; Özelt, Harald; Kovacs, Alexander; Brandl, Martin; Schrefl, Thomas

2014-02-01

Micromagnetic beads are widely used in biomedical applications for cell separation, drug delivery, and hyperthermia cancer treatment. Here we propose to use self-organized magnetic bead structures which accumulate on fixed magnetic seeding points to isolate circulating tumor cells. The analysis of circulating tumor cells is an emerging tool for cancer biology research and clinical cancer management including the detection, diagnosis and monitoring of cancer. Microfluidic chips for isolating circulating tumor cells use either affinity, size or density capturing methods. We combine multiphysics simulation techniques to understand the microscopic behavior of magnetic beads interacting with soft magnetic accumulation points used in lab-on-chip technologies. Our proposed chip technology offers the possibility to combine affinity and size capturing with special antibody-coated bead arrangements using a magnetic gradient field created by Neodymium Iron Boron permanent magnets. The multiscale simulation environment combines magnetic field computation, fluid dynamics and discrete particle dynamics.

Metaphotonics: An emerging field with opportunities and challenges

NASA Astrophysics Data System (ADS)

Baev, Alexander; Prasad, Paras N.; Ågren, Hans; Samoć, Marek; Wegener, Martin

2015-09-01

Metaphotonics is an emerging multidisciplinary field that deals with manipulation of electro-magnetic fields in nanoengineered (meta)materials using both electric and magnetic interactions and their cross-coupling. It offers unprecedented control of both linear and nonlinear optical functions for applications ranging from optical switching, to negative- and near-zero refractive index metamaterials, to chiral bioimaging, to cloaking. However, realization of such applications requires physics-guided nanoengineering of appropriate artificial media with electro-magnetic properties at visible and infrared wavelengths that are tailored to surpass those of any naturally-occurring material. Here, we review metaphotonics with a broadened vision and scope, introduce potential applications, describe the role of theoretical physics through multiscale modeling, review the materials development and current status, and outline opportunities in this fertile emerging field.

Modeling of field-aligned guided echoes in the plasmasphere

NASA Astrophysics Data System (ADS)

Fung, Shing F.; Green, James L.

2005-01-01

Ray tracing modeling is used to investigate the plasma conditions under which high-frequency (f ≫ fuh) extraordinary mode waves can be guided along geomagnetic field lines. These guided signals have often been observed as long-range discrete echoes in the plasmasphere by the Radio Plasma Imager (RPI) onboard the Imager for Magnetopause-to-Aurora Global Exploration satellite. Field-aligned discrete echoes are most commonly observed by RPI in the plasmasphere, although they are also observed over the polar cap region. The plasmasphere field-aligned echoes appearing as multiple echo traces at different virtual ranges are attributed to signals reflected successively between conjugate hemispheres that propagate along or nearly along closed geomagnetic field lines. The ray tracing simulations show that field-aligned ducts with as little as 1% density perturbations (depletions) and <10 wavelengths wide can guide nearly field-aligned propagating high-frequency X mode waves. Effective guidance of a wave at a given frequency and wave normal angle (Ψ) depends on the cross-field density scale of the duct, such that ducts with stronger density depletions need to be wider in order to maintain the same gradient of refractive index across the magnetic field. While signal guidance by field aligned density gradient without ducting is possible only over the polar region, conjugate field-aligned echoes that have traversed through the equatorial region are most likely guided by ducting.

Remote Sensing of the Reconnection Electric Field From In Situ Multipoint Observations of the Separatrix Boundary

NASA Astrophysics Data System (ADS)

Nakamura, T. K. M.; Nakamura, R.; Varsani, A.; Genestreti, K. J.; Baumjohann, W.; Liu, Y.-H.

2018-05-01

A remote sensing technique to infer the local reconnection electric field based on in situ multipoint spacecraft observation at the reconnection separatrix is proposed. In this technique, the increment of the reconnected magnetic flux is estimated by integrating the in-plane magnetic field during the sequential observation of the separatrix boundary by multipoint measurements. We tested this technique by applying it to virtual observations in a two-dimensional fully kinetic particle-in-cell simulation of magnetic reconnection without a guide field and confirmed that the estimated reconnection electric field indeed agrees well with the exact value computed at the X-line. We then applied this technique to an event observed by the Magnetospheric Multiscale mission when crossing an energetic plasma sheet boundary layer during an intense substorm. The estimated reconnection electric field for this event is nearly 1 order of magnitude higher than a typical value of magnetotail reconnection.

Using ferromagnetic nanoparticles with low Curie temperature for magnetic resonance imaging-guided thermoablation.

PubMed

Herynek, Vít; Turnovcová, Karolína; Veverka, Pavel; Dědourková, Tereza; Žvátora, Pavel; Jendelová, Pavla; Gálisová, Andrea; Kosinová, Lucie; Jiráková, Klára; Syková, Eva

2016-01-01

Magnetic nanoparticles (NPs) represent a tool for use in magnetic resonance imaging (MRI)-guided thermoablation of tumors using an external high-frequency (HF) magnetic field. To avoid local overheating, perovskite NPs with a lower Curie temperature (T c) were proposed for use in thermotherapy. However, deposited power decreases when approaching the Curie temperature and consequently may not be sufficient for effective ablation. The goal of the study was to test this hypothesis. Perovskite NPs (T c =66°C-74°C) were characterized and tested both in vitro and in vivo. In vitro, the cells suspended with NPs were exposed to a HF magnetic field together with control samples. In vivo, a NP suspension was injected into a induced tumor in rats. Distribution was checked by MRI and the rats were exposed to a HF field together with control animals. Apoptosis in the tissue was evaluated. In vitro, the high concentration of suspended NPs caused an increase of the temperature in the cell sample, leading to cell death. In vivo, MRI confirmed distribution of the NPs in the tumor. The temperature in the tumor with injected NPs did not increase substantially in comparison with animals without particles during HF exposure. We proved that the deposited power from the NPs is too small and that thermoregulation of the animal is sufficient to conduct the heat away. Histology did not detect substantially higher apoptosis in NP-treated animals after ablation. Magnetic particles with low T c can be tracked in vivo by MRI and heated by a HF field. The particles are capable of inducing cell apoptosis in suspensions in vitro at high concentrations only. However, their effect in the case of extracellular deposition in vivo is questionable due to low deposited power and active thermoregulation of the tissue.

New Measure of the Dissipation Region in Collisionless Magnetic Reconnection

NASA Technical Reports Server (NTRS)

Zenitani, Seiji; Hesse, Michael; Klimas, Alex; Kuznetsova, Masha

2012-01-01

A new measure to identify a small-scale dissipation region in collisionless magnetic reconnection is proposed. The energy transfer from the electromagnetic field to plasmas in the electron s rest frame is formulated as a Lorentz-invariant scalar quantity. The measure is tested by two-dimensional particle-in-cell simulations in typical configurations: symmetric and asymmetric reconnection, with and without the guide field. The innermost region surrounding the reconnection site is accurately located in all cases. We further discuss implications for nonideal MHD dissipation.

New Measure of the Dissipation Region in Collisionless Magnetic Reconnection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zenitani, Seiji; Hesse, Michael; Klimas, Alex

2011-05-13

A new measure to identify a small-scale dissipation region in collisionless magnetic reconnection is proposed. The energy transfer from the electromagnetic field to plasmas in the electron's rest frame is formulated as a Lorentz-invariant scalar quantity. The measure is tested by two-dimensional particle-in-cell simulations in typical configurations: symmetric and asymmetric reconnection, with and without the guide field. The innermost region surrounding the reconnection site is accurately located in all cases. We further discuss implications for nonideal MHD dissipation.

Coupling Influences SMM Properties for Pure 4 f Systems.

PubMed

Zhang, Xuejing; Liu, Shuang; Vieru, Veacheslav; Xu, Na; Gao, Chen; Wang, Bing-Wu; Shi, Wei; Chibotaru, Liviu F; Gao, Song; Cheng, Peng; Powell, Annie K

2018-04-20

Increasing both the energy barrier for magnetization reversal and the coercive field of the hysteresis loop are significant challenges in the field of single-molecule magnets (SMMs). Coordination geometries of lanthanide ions and magnetic interactions between lanthanide ions are both important for guiding the magnetic behavior of SMMs. We report a high energy barrier of 657 K (457 cm -1 ) in a diamagnetic-ion-diluted lanthanide chain compound with a constrained bisphenoid symmetry (D 2d ); this energy barrier is substantially higher than the barrier of 567 K (394 cm -1 ) of the non-diluted chain compound with intrachain ferromagnetic interactions. Although intrachain magnetic interaction lowers the energy barrier for magnetization reversal, it can greatly enhance the coercive fields and zero-field remanence of the hysteresis loops, which is crucial for the rational design of high-performance SMMs. Factors related to the coordination sphere of the lanthanide center, which govern the high magnetic relaxation barriers through the second excited Kramer's doublets and the magnetic interactions that affect the hysteresis loops, were revealed through ab initio calculations. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Study on the creation and destruction of transport barriers via the effective safety factors for energetic particles

NASA Astrophysics Data System (ADS)

Ogawa, Shun; Leoncini, Xavier; Dif-Pradalier, Guilhem; Garbet, Xavier

2016-12-01

Charged particles with low kinetic energy move along the magnetic field lines, but so do not the energetic particles. We investigate the topological structure changes in the phase space of energetic particles with respect to the magnetic one. For this study, cylindrical magnetic fields with non-monotonic safety factors that induce the magnetic internal transport barrier are considered. We show that the topological structure of the magnetic field line and of the particle trajectories can be quite different. We explain this difference using the concept of an effective particle q-profile. Using this notion, we can investigate the location and existence of resonances for particle orbits that are different from the magnetic ones. These are examined both numerically by integrating an equation of motion and theoretically by the use of Alfvén's guiding center theory and by the use of an effective reduced Hamiltonian for the integrable unperturbed system. It is clarified that, for the energetic particles, the grad B drift effect shifts the resonances and the drift induced by curvature of the magnetic field line leads to the vanishing of the resonances. As a result, we give two different mechanisms that lead to the creation of transport barriers for energetic particles in the region where the magnetic field line is chaotic.

A superconducting conveyer system using multiple bulk Y-Ba-Cu-O superconductors and permanent magnets

NASA Astrophysics Data System (ADS)

Kinoshita, T.; Koshizuka, N.; Nagashima, K.; Murakami, M.

Developments of non-contact superconducting devices like superconducting magnetic levitation transfer and superconducting flywheel energy storage system have been performed based on the interactions between bulk Y-Ba-Cu-O superconductors and permanent magnets, in that the superconductors can stably be levitated without any active control. The performances of noncontact superconducting devices are dependent on the interaction forces like attractive forces and stiffness. In the present study, we constructed a non-contact conveyer for which the guide rails were prepared by attaching many Fe-Nd-B magnets onto an iron base plate. Along the translational direction, all the magnets were arranged as to face the same pole, and furthermore their inter-distance was made as small as possible. The guide rail has three magnet rows, for which the magnets were glued on the iron plate such that adjacent magnet rows have opposite poles like NSN. At the center row, the magnetic field at zero gap reached 0.61T, while the field strengths of two rows on the side edges were only 0.48T due to magnetic interactions among permanent magnets. We then prepared a cryogenic box made with FRP that can store several bulk Y-Ba-Cu-O superconductors 25 mm in diameter cooled by liquid nitrogen. It was found that the levitation forces and stiffness increased with increasing the number of bulk superconductors installed in the box, although the levitation force per unit bulk were almost the same. We also confirmed that these forces are dependent on the configuration of bulk superconductors.

Effects of Current Guides Destruction at Ultra-fast Acceleration of Macrobodies

NASA Astrophysics Data System (ADS)

Kataev, V. N.; Boriskin, A. S.; Golosov, S. N.; Demidov, V. A.; Klimashov, M. V.; Korolev, P. V.; Makartsev, G. F.; Pikar, A. S.; Russkov, A. S.; Shapovalov, E. V.; Shibitov, Yu. M.

2006-08-01

The paper is devoted to discussion of current guides destruction effects in different accelerators: thermal-electric and electro-magnetic rail accelerator at macrobodies acceleration value of 108-109 m/s2. Experimental results with thermal-electric accelerators powering from megajoule capacitor battery and helical magneto-cumulative generator MCG-100 at currents up to 3.5 MA are analyzed. The process of rails destruction at railgun at pressure magnetic field excess over the limit of metal fluidity is presented. Methods of efficiency coefficient increase of capacitive storage energy transmission to kinetic energy of accelerating body are discussed.

APPARATUS FOR TRAPPING ENERGETIC CHARGED PARTICLES AND CONFINING THE RESULTING PLASMA

DOEpatents

Gibson, G.; Jordan, W.C.; Lauer, E.J.

1963-04-01

The present invention relates to a plasma-confining device and a particle injector therefor, the device utilizing a generally toroidal configuration with magnetic fields specifically tailored to the associated injector. The device minimizes the effects of particle end losses and particle drift to the walls with a relatively simple configuration. More particularly, the magnetic field configuration is created by a continuous array of circular, mirror field coils, disposed side-by- side, in particularly spaced relation, to form an endless, toroidal loop. The resulting magnetic field created therein has the appearance of a bumpy'' torus, from which is derived the name Bumpy Torus.'' One of the aforementioned coils is split transverse to its axis, and injection of particles is accomplished along a plane between the halves of such modified coil. The guiding center of the particles follows a constant magnetic field in the plane for a particular distance within the torus, to move therefrom onto a precessional surface which does not intersect the point of injection. (AEC)

Electromagnetic Ion Cyclotron Waves in the High Altitude Cusp: Polar Observations

NASA Technical Reports Server (NTRS)

Le, Guan; Blanco-Cano, X.; Russell, C. T.; Zhou, X.-W.; Mozer, F.; Trattner, K. J.; Fuselier, S. A.; Anderson, B. J.; Vondrak, Richard R. (Technical Monitor)

2001-01-01

High-resolution magnetic field data from the Polar Magnetic Field Experiment (MFE) show that narrow band waves at frequencies approximately 0.2 to 3 Hz are a permanent feature in the vicinity of the polar cusp. The waves have been found in the magnetosphere adjacent to the cusp (both poleward and equatorward of the cusp) and in the cusp itself. The occurrence of waves is coincident with depression of magnetic field strength associated with enhanced plasma density, indicating the entry of magnetosheath plasma into the cusp region. The wave frequencies are generally scaled by the local proton cyclotron frequency, and vary between 0.2 and 1.7 times local proton cyclotron frequency. This suggests that the waves are generated in the cusp region by the precipitating magnetosheath plasma. The properties of the waves are highly variable. The waves exhibit both lefthanded and right-handed polarization in the spacecraft frame. The propagation angles vary from nearly parallel to nearly perpendicular to the magnetic field. We find no correlation among wave frequency, propagation angle and polarization. Combined magnetic field and electric field data for the waves indicate that the energy flux of the waves is guided by the background magnetic field and points downward toward the ionosphere.

Electromagnetic Ion Cyclotron Waves in the High-Altitude Cusp: Polar Observations

NASA Technical Reports Server (NTRS)

Le, G.; Blanco-Cano, X.; Russell, C. T.; Zhou, X.-W.; Mozer, F.; Trattner, K. J.; Fuselier, S. A.; Anderson, B. J.

2005-01-01

High-resolution magnetic field data from the Polar Magnetic Field Experiment (MFE) show that narrow-band waves at frequencies approx. 0.2-3 Hz are a permanent feature in the vicinity of the polar cusp. The waves have been found in the magnetosphere adjacent to the cusp (both poleward and equatorward of the cusp) and in the cusp itself. The occurrence of waves is coincident with depression of magnetic field strength associated with enhanced plasma density, indicating the entry of magnetosheath plasma into the cusp region. The wave frequencies are generally scaled by the local proton cyclotron frequency and vary between 0.2 and 1.7 times local proton cyclotron frequency. This suggests that the waves are generated in the cusp region by the precipitating magnetosheath plasma. The properties of the waves are highly variable. The waves exhibit both left-handed and right-handed polarization in the spacecraft frame. The propagation angles vary from nearly parallel to nearly perpendicular to the magnetic field. We find no correlation among wave frequency, propagation angle, and polarization. Combined magnetic field and electric field data for the waves indicate that the energy flux of the waves is guided by the background magnetic field and points downward toward the ionosphere.

Charge neutralization apparatus for ion implantation system

DOEpatents

Leung, Ka-Ngo; Kunkel, Wulf B.; Williams, Malcom D.; McKenna, Charles M.

1992-01-01

Methods and apparatus for neutralization of a workpiece such as a semiconductor wafer in a system wherein a beam of positive ions is applied to the workpiece. The apparatus includes an electron source for generating an electron beam and a magnetic assembly for generating a magnetic field for guiding the electron beam to the workpiece. The electron beam path preferably includes a first section between the electron source and the ion beam and a second section which is coincident with the ion beam. The magnetic assembly generates an axial component of magnetic field along the electron beam path. The magnetic assembly also generates a transverse component of the magnetic field in an elbow region between the first and second sections of the electron beam path. The electron source preferably includes a large area lanthanum hexaboride cathode and an extraction grid positioned in close proximity to the cathode. The apparatus provides a high current, low energy electron beam for neutralizing charge buildup on the workpiece.

Guiding thermomagnetic avalanches with soft magnetic stripes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vlasko-Vlasov, V. K.; Colauto, F.; Benseman, T.

We demonstrate the potential for manipulating the ultrafast dynamics of thermomagnetic flux avalanches (TMA) in superconducting films with soft magnetic stripes deposited on the film. By tuning the in-plane magnetization of the stripes, we induce lines of strong magnetic potentials for Abrikosov vortices, resulting in guided slow motion of vortices along the stripe edges and preferential bursts of TMA along the stripes. Furthermore, we show that transversely polarized stripes can reduce the TMA size by diverting magnetic flux away from the major trunk of the TMA into interstripe gaps. Our data indicate that TMAs are launched from locations with enhancedmore » vortex entry barrier, where flux accumulation followed by accelerated vortex discharge significantly reduces the threshold of the applied field ramping speed required for the creation of TMAs. Finally, vortex-antivortex annihilation at the moving front of an expanding TMA can account for the enhanced TMA activity in the receding branches of the sample's magnetization cycle and the preferred propagation of TMAs into maximum trapped flux regions.« less

Guiding thermomagnetic avalanches with soft magnetic stripes

NASA Astrophysics Data System (ADS)

Vlasko-Vlasov, V. K.; Colauto, F.; Benseman, T.; Rosenmann, D.; Kwok, W.-K.

2017-12-01

We demonstrate the potential for manipulating the ultrafast dynamics of thermomagnetic flux avalanches (TMA) in superconducting films with soft magnetic stripes deposited on the film. By tuning the in-plane magnetization of the stripes, we induce lines of strong magnetic potentials for Abrikosov vortices, resulting in guided slow motion of vortices along the stripe edges and preferential bursts of TMA along the stripes. Furthermore, we show that transversely polarized stripes can reduce the TMA size by diverting magnetic flux away from the major trunk of the TMA into interstripe gaps. Our data indicate that TMAs are launched from locations with enhanced vortex entry barrier, where flux accumulation followed by accelerated vortex discharge significantly reduces the threshold of the applied field ramping speed required for the creation of TMAs. Finally, vortex-antivortex annihilation at the moving front of an expanding TMA can account for the enhanced TMA activity in the receding branches of the sample's magnetization cycle and the preferred propagation of TMAs into maximum trapped flux regions.

Atomic magnetometer-based ultra-sensitive magnetic microscopy

NASA Astrophysics Data System (ADS)

Kim, Young Jin; Savukov, Igor

2016-03-01

An atomic magnetometer (AM) based on lasers and alkali-metal vapor cells is currently the most sensitive non-cryogenic magnetic-field sensor. Many applications in neuroscience and other fields require high resolution, high sensitivity magnetic microscopic measurements. In order to meet this need we combined a cm-size spin-exchange relaxation-free AM with a flux guide (FG) to produce an ultra-sensitive FG-AM magnetic microscope. The FG serves to transmit the target magnetic flux to the AM thus enhancing both the sensitivity and resolution for tiny magnetic objects. In this talk, we will describe a prototype FG-AM device and present experimental and numerical tests of its sensitivity and resolution. We also demonstrate that an optimized FG-AM achieves high resolution and high sensitivity sufficient to detect a magnetic field of a single neuron in a few seconds, which would be an important milestone in neuroscience. We anticipate that this unique device can be applied to the detection of a single neuron, the detection of magnetic nano-particles, which in turn are very important for detection of target molecules in national security and medical diagnostics, and non-destructive testing.

First experimental demonstration of magnetic-field assisted fast heating of a dense plasma core

NASA Astrophysics Data System (ADS)

Fujioka, Shinsuke; Sakata, Shohei; Lee, Seung Ho; Matsuo, Kazuki; Sawada, Hiroshi; Iwasa, Yuki; Law, King Fai Farley; Morita, Hitoki; Kojima, Sadaoki; Abe, Yuki; Yao, Akira; Hata, Masayasu; Johzaki, Tomoyuki; Sunahara, Atsushi; Ozaki, Tetsuo; Sakagami, Hitoshi; Morace, Alessio; Arikawa, Yasunobu; Yogo, Akifumi; Nishimura, Hiroaki; Nakai, Mitsuo; Shiraga, Hiroyuki; Sentoku, Yasuhiko; Nagatomo, Hideo; Azechi, Hiroshi; Firex Project Team

2016-10-01

Fast heating of a dense plasma core by an energetic electron beam is being studied on GEKKO-LFEX laser facility. Here, we introduce a laser-driven kilo-tesla external magnetic field to guide the diverging electron beam to the dense plasma core. This involve placing a spherical target in the magnetic field, compressing it with the GEKKO-XII laser beams and then using the LFEX laser beams injected into the dense plasma to generate the electron beam which do the fast heating. Cu-Ka emission is used to visualize transport or heating processes of a dense plasma. X-ray spectrum from a highly ionized Cu ions indicates several keV of the temperature increment induced by the LFEX.

Accuracy of low-field magnetic resonance imaging versus radiography for guiding injection of equine distal interphalangeal joint collateral ligaments.

PubMed

Lamb, Megan M; Barrett, Jennifer G; White, Nathaniel A; Werre, Stephen R

2014-01-01

Desmopathy of the distal interphalangeal joint collateral ligament is a common cause of lameness in the horse and carries a variable prognosis for soundness. Intralesional treatment has been proposed for improving outcome; however, limited reports describe methods for injecting this ligament. The purpose of this study was to compare accuracy of low-field magnetic resonance imaging (MRI) vs. radiography for injecting the collateral ligament of the distal interphalangeal joint. Equine cadaver digit pairs (n = 10) were divided by random assignment to injection of the ligament by either technique. An observer unaware of injection technique determined injection success based on postinjection MRI and/or gross sections acquired from the proximal, middle, and distal portions of the ligament. McNemar's test was performed to determine statistical difference between injection techniques, the number of injection attempts, and injection of the medial or lateral collateral ligament. Magnetic resonance imaging guided injection was successful more frequently than radiographic-guided injection based on postinjection MRI (24 of 30 vs. 9 of 30; P = 0.0006) and gross sections (26 of 30 vs. 13 of 30; P = 0.0008). At each level of the ligament (proximal, middle, and distal), MRI-guided injection resulted in more successful injections than radiographic guidance. Statistical significance occurred at the proximal aspect of the collateral ligament based on postinjection MRI (P = 0.0143) and the middle portion of the ligament based on gross sections (P = 0.0253). Findings supported future testing of standing, low-field MRI as a technique for delivering intralesional regenerative therapy in live horses with desmopathy of these collateral ligaments. © 2013 American College of Veterinary Radiology.

Effect of a magnetic field on the track structure of low-energy electrons: a Monte Carlo study

NASA Astrophysics Data System (ADS)

Bug, M. U.; Gargioni, E.; Guatelli, S.; Incerti, S.; Rabus, H.; Schulte, R.; Rosenfeld, A. B.

2010-10-01

The increasing use of MRI-guided radiation therapy evokes the necessity to investigate the potential impact of a magnetic field on the biological effectiveness of therapeutic radiation beams. While it is known that a magnetic field, applied during irradiation, can improve the macroscopic absorbed dose distribution of electrons in the tumor region, effects on the microscopic distribution of energy depositions and ionizations have not yet been investigated. An effect on the number of ionizations in a DNA segment, which is related to initial DNA damage in form of complex strand breaks, could be beneficial in radiation therapy. In this work we studied the effects of a magnetic field on the pattern of ionizations at nanometric level by means of Monte Carlo simulations using the Geant4-DNA toolkit. The track structure of low-energy electrons in the presence of a uniform static magnetic field of strength up to 14 T was calculated for a simplified DNA segment model in form of a water cylinder. In the case that no magnetic field is applied, nanodosimetric results obtained with Geant4-DNA were compared with those from the PTB track structure code. The obtained results suggest that any potential enhancement of complexity of DNA strand breaks induced by irradiation in a magnetic field is not related to modifications of the low-energy secondary electrons track structure.

Waves and Particles, The Orbital Atom, Parts One and Two of an Integrated Science Sequence, Teacher's Guide, 1973 Edition.

ERIC Educational Resources Information Center

Portland Project Committee, OR.

This teacher's guide includes parts one and two of the four-part third year Portland Project, a three-year integrated secondary science curriculum sequence. The Harvard Project Physics textbook is used for reading assignments for part one. Assignments relate to waves, light, electricity, magnetic fields, Faraday and the electrical age,…

Magnetically guided capsule endoscopy.

PubMed

Shamsudhin, Naveen; Zverev, Vladimir I; Keller, Henrik; Pane, Salvador; Egolf, Peter W; Nelson, Bradley J; Tishin, Alexander M

2017-08-01

Wireless capsule endoscopy (WCE) is a powerful tool for medical screening and diagnosis, where a small capsule is swallowed and moved by means of natural peristalsis and gravity through the human gastrointestinal (GI) tract. The camera-integrated capsule allows for visualization of the small intestine, a region which was previously inaccessible to classical flexible endoscopy. As a diagnostic tool, it allows to localize the sources of bleedings in the middle part of the gastrointestinal tract and to identify diseases, such as inflammatory bowel disease (Crohn's disease), polyposis syndrome, and tumors. The screening and diagnostic efficacy of the WCE, especially in the stomach region, is hampered by a variety of technical challenges like the lack of active capsular position and orientation control. Therapeutic functionality is absent in most commercial capsules, due to constraints in capsular volume and energy storage. The possibility of using body-exogenous magnetic fields to guide, orient, power, and operate the capsule and its mechanisms has led to increasing research in Magnetically Guided Capsule Endoscopy (MGCE). This work shortly reviews the history and state-of-art in WCE technology. It highlights the magnetic technologies for advancing diagnostic and therapeutic functionalities of WCE. Not restricting itself to the GI tract, the review further investigates the technological developments in magnetically guided microrobots that can navigate through the various air- and fluid-filled lumina and cavities in the body for minimally invasive medicine. © 2017 American Association of Physicists in Medicine.

A millimeter wave relativistic backward wave oscillator operating in TM{sub 03} mode with low guiding magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ye, Hu; Wu, Ping; Science and Technology on High Power Microwave Laboratory, Northwest Institute of Nuclear Technology, Xi'an Shaanxi 710024

2015-06-15

A V-band overmoded relativistic backward wave oscillator (RBWO) guided by low magnetic field and operating on a TM{sub 03} mode is presented to increase both the power handling capacity and the wave-beam interaction conversion efficiency. Trapezoidal slow wave structures (SWSs) with shallow corrugations and long periods are adopted to make the group velocity of TM{sub 03} mode at the intersection point close to zero. The coupling impedance and diffraction Q-factor of the RBWO increase, while the starting current decreases owing to the reduction of the group velocity of TM{sub 03} mode. In addition, the TM{sub 03} mode dominates over themore » other modes in the startup of the oscillation. Via numerical simulation, the generation of the microwave pulse with an output power of 425 MW and a conversion efficiency of 32% are achieved at 60.5 GHz with an external magnetic field of 1.25 T. This RBWO can provide greater power handling capacity when operating on the TM{sub 03} mode than on the TM{sub 01} mode.« less

Nonthermal Particle Acceleration in 3D Relativistic Magnetic Reconnection in Pair Plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Werner, Gregory R.; Uzdensky, Dmitri A., E-mail: Greg.Werner@colorado.edu

As a fundamental process converting magnetic to plasma energy in high-energy astrophysical plasmas, relativistic magnetic reconnection is a leading explanation for the acceleration of particles to the ultrarelativistic energies that are necessary to power nonthermal emission (especially X-rays and gamma-rays) in pulsar magnetospheres and pulsar wind nebulae, coronae and jets of accreting black holes, and gamma-ray bursts. An important objective of plasma astrophysics is therefore the characterization of nonthermal particle acceleration (NTPA) effected by reconnection. Reconnection-powered NTPA has been demonstrated over a wide range of physical conditions using large 2D kinetic simulations. However, its robustness in realistic 3D reconnection—in particular,more » whether the 3D relativistic drift-kink instability (RDKI) disrupts NTPA—has not been systematically investigated, although pioneering 3D simulations have observed NTPA in isolated cases. Here, we present the first comprehensive study of NTPA in 3D relativistic reconnection in collisionless electron–positron plasmas, characterizing NTPA as the strength of 3D effects is varied systematically via the length in the third dimension and the strength of the guide magnetic field. We find that, while the RDKI prominently perturbs 3D reconnecting current sheets, it does not suppress particle acceleration, even for zero guide field; fully 3D reconnection robustly and efficiently produces nonthermal power-law particle spectra closely resembling those obtained in 2D. This finding provides strong support for reconnection as the key mechanism powering high-energy flares in various astrophysical systems. We also show that strong guide fields significantly inhibit NTPA, slowing reconnection and limiting the energy available for plasma energization, yielding steeper and shorter power-law spectra.« less

Multi-scale structures of turbulent magnetic reconnection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nakamura, T. K. M., E-mail: takuma.nakamura@oeaw.ac.at; Nakamura, R.; Narita, Y.

2016-05-15

We have analyzed data from a series of 3D fully kinetic simulations of turbulent magnetic reconnection with a guide field. A new concept of the guide filed reconnection process has recently been proposed, in which the secondary tearing instability and the resulting formation of oblique, small scale flux ropes largely disturb the structure of the primary reconnection layer and lead to 3D turbulent features [W. Daughton et al., Nat. Phys. 7, 539 (2011)]. In this paper, we further investigate the multi-scale physics in this turbulent, guide field reconnection process by introducing a wave number band-pass filter (k-BPF) technique in whichmore » modes for the small scale (less than ion scale) fluctuations and the background large scale (more than ion scale) variations are separately reconstructed from the wave number domain to the spatial domain in the inverse Fourier transform process. Combining with the Fourier based analyses in the wave number domain, we successfully identify spatial and temporal development of the multi-scale structures in the turbulent reconnection process. When considering a strong guide field, the small scale tearing mode and the resulting flux ropes develop over a specific range of oblique angles mainly along the edge of the primary ion scale flux ropes and reconnection separatrix. The rapid merging of these small scale modes leads to a smooth energy spectrum connecting ion and electron scales. When the guide field is sufficiently weak, the background current sheet is strongly kinked and oblique angles for the small scale modes are widely scattered at the kinked regions. Similar approaches handling both the wave number and spatial domains will be applicable to the data from multipoint, high-resolution spacecraft observations such as the NASA magnetospheric multiscale (MMS) mission.« less

Multi-scale structures of turbulent magnetic reconnection

NASA Astrophysics Data System (ADS)

Nakamura, T. K. M.; Nakamura, R.; Narita, Y.; Baumjohann, W.; Daughton, W.

2016-05-01

We have analyzed data from a series of 3D fully kinetic simulations of turbulent magnetic reconnection with a guide field. A new concept of the guide filed reconnection process has recently been proposed, in which the secondary tearing instability and the resulting formation of oblique, small scale flux ropes largely disturb the structure of the primary reconnection layer and lead to 3D turbulent features [W. Daughton et al., Nat. Phys. 7, 539 (2011)]. In this paper, we further investigate the multi-scale physics in this turbulent, guide field reconnection process by introducing a wave number band-pass filter (k-BPF) technique in which modes for the small scale (less than ion scale) fluctuations and the background large scale (more than ion scale) variations are separately reconstructed from the wave number domain to the spatial domain in the inverse Fourier transform process. Combining with the Fourier based analyses in the wave number domain, we successfully identify spatial and temporal development of the multi-scale structures in the turbulent reconnection process. When considering a strong guide field, the small scale tearing mode and the resulting flux ropes develop over a specific range of oblique angles mainly along the edge of the primary ion scale flux ropes and reconnection separatrix. The rapid merging of these small scale modes leads to a smooth energy spectrum connecting ion and electron scales. When the guide field is sufficiently weak, the background current sheet is strongly kinked and oblique angles for the small scale modes are widely scattered at the kinked regions. Similar approaches handling both the wave number and spatial domains will be applicable to the data from multipoint, high-resolution spacecraft observations such as the NASA magnetospheric multiscale (MMS) mission.

GigaGauss solenoidal magnetic field inside bubbles excited in under-dense plasma

PubMed Central

Lécz, Zs.; Konoplev, I. V.; Seryi, A.; Andreev, A.

2016-01-01

This paper proposes a novel and effective method for generating GigaGauss level, solenoidal quasi-static magnetic fields in under-dense plasma using screw-shaped high intensity laser pulses. This method produces large solenoidal fields that move with the driving laser pulse and are collinear with the accelerated electrons. This is in contrast with already known techniques which rely on interactions with over-dense or solid targets and generates radial or toroidal magnetic field localized at the stationary target. The solenoidal field is quasi-stationary in the reference frame of the laser pulse and can be used for guiding electron beams. It can also provide synchrotron radiation beam emittance cooling for laser-plasma accelerated electron and positron beams, opening up novel opportunities for designs of the light sources, free electron lasers, and high energy colliders based on laser plasma acceleration. PMID:27796327

The analysis of single-electron orbits in a free electron laser based upon a rectangular hybrid wiggler

NASA Astrophysics Data System (ADS)

Kordbacheh, A.; Ghahremaninezhad, Roghayeh; Maraghechi, B.

2012-09-01

A three-dimensional analysis of a novel free-electron laser (FEL) based upon a rectangular hybrid wiggler (RHW) is presented. This RHW is designed in a configuration composed of rectangular rings with alternating ferrite and dielectric spacers immersed in a solenoidal magnetic field. An analytic model of RHW is introduced by solution of Laplace's equation for the magnetostatic fields under the appropriate boundary conditions. The single-electron orbits in combined RHW and axial guide magnetic fields are studied when only the first and the third spatial harmonic components of the RHW field are taken into account and the higher order terms are ignored. The results indicate that the third spatial harmonic leads to group III orbits with a strong negative mass regime particularly in large solenoidal magnetic fields. RHW is found to be a promising candidate with favorable characteristics to be used in microwave FEL.

GigaGauss solenoidal magnetic field inside bubbles excited in under-dense plasma

NASA Astrophysics Data System (ADS)

Lécz, Zs.; Konoplev, I. V.; Seryi, A.; Andreev, A.

2016-10-01

This paper proposes a novel and effective method for generating GigaGauss level, solenoidal quasi-static magnetic fields in under-dense plasma using screw-shaped high intensity laser pulses. This method produces large solenoidal fields that move with the driving laser pulse and are collinear with the accelerated electrons. This is in contrast with already known techniques which rely on interactions with over-dense or solid targets and generates radial or toroidal magnetic field localized at the stationary target. The solenoidal field is quasi-stationary in the reference frame of the laser pulse and can be used for guiding electron beams. It can also provide synchrotron radiation beam emittance cooling for laser-plasma accelerated electron and positron beams, opening up novel opportunities for designs of the light sources, free electron lasers, and high energy colliders based on laser plasma acceleration.

Guided flows in coronal magnetic flux tubes

NASA Astrophysics Data System (ADS)

Petralia, A.; Reale, F.; Testa, P.

2018-01-01

Context. There is evidence that coronal plasma flows break down into fragments and become laminar. Aims: We investigate this effect by modelling flows confined along magnetic channels. Methods: We consider a full magnetohydrodynamic (MHD) model of a solar atmosphere box with a dipole magnetic field. We compare the propagation of a cylindrical flow perfectly aligned with the field to that of another flow with a slight misalignment. We assume a flow speed of 200 km s-1 and an ambient magnetic field of 30 G. Results: We find that although the aligned flow maintains its cylindrical symmetry while it travels along the magnetic tube, the misaligned one is rapidly squashed on one side, becoming laminar and eventually fragmented because of the interaction and back-reaction of the magnetic field. This model could explain an observation made by the Atmospheric Imaging Assembly on board the Solar Dynamics Observatory of erupted fragments that fall back onto the solar surface as thin and elongated strands and end up in a hedge-like configuration. Conclusions: The initial alignment of plasma flow plays an important role in determining the possible laminar structure and fragmentation of flows while they travel along magnetic channels. Movies are available in electronic form at http://www.aanda.org

Particle confinement by a radially polarized laser Bessel beam

NASA Astrophysics Data System (ADS)

Laredo, Gilad; Kimura, Wayne D.; Schächter, Levi

2017-03-01

The stable trajectory of a charged particle in an external guiding field is an essential condition for its acceleration or for forcing it to generate radiation. Examples of possible guiding devices include a solenoidal magnetic field or permanent periodic magnet in klystrons, a wiggler in free-electron lasers, the lattice of any accelerator, and finally the crystal lattice for the case of channeling radiation. We demonstrate that the trajectory of a point-charge in a radially polarized laser Bessel beam may be stable similarly to the case of a positron that bounces back and forth in the potential well generated by two adjacent atomic planes. While in the case of channeling radiation, the transverse motion is controlled by a harmonic oscillator equation, for a Bessel beam the transverse motion is controlled by the Mathieu equation. Some characteristics of the motion are presented.

Analytical solutions and particle simulations of cross-field plasma sheaths

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gerver, M.J.; Parker, S.E.; Theilhaber, K.

1989-08-30

Particles simulations have been made of an infinite plasma slab, bounded by absorbing conducting walls, with a magnetic field parallel to the walls. The simulations have been either 1-D, or 2-D, with the magnetic field normal to the simulation plane. Initially, the plasma has a uniform density between the walls, and there is a uniform source of ions and electrons to replace particles lost to the walls. In the 1-D case, there is no diffusion of the particle guiding centers, and the plasma remains uniform in density and potential over most of the slab, with sheaths about a Debye lengthmore » wide where the potential rises to the wall potential. In the 2-D case, the density profile becomes parabolic, going almost to zero at the walls, and there is a quasineutral presheath in the bulk of the plasma, in addition to sheaths near the walls. Analytic expressions are found for the density and potential profiles in both cases, including, in the 2-D case, the magnetic presheath due to finite ion Larmor radius, and the effects of the guiding center diffusion rate being either much less than or much grater than the energy diffusion rate. These analytic expressions are shown to agree with the simulations. A 1-D simulation with Monte Carlo guiding center diffusion included gives results that are good agreement with the much more expensive 2-D simulation. 17 refs., 10 figs.« less

Fast magnetic reconnection with large guide fields

DOE PAGES

Stanier, A.; Simakov, Andrei N.; Chacón, L.; ...

2015-01-09

We domonstrate, using two-fluid simulations, that low-βmagnetic reconnection remains fast, regardless of the presence of fast dispersive waves, which have been previously suggested to play a critical role. In order to understand these results, a discrete model is constructed that offers scaling relationships for the reconnection rate and dissipation region (DR) thickness in terms of the upstream magnetic field and DR length. Moreover, we verify these scalings numerically and show how the DR self-adjusts to process magnetic flux at the same rate that it is supplied to a larger region where two-fluid effects become important. The rate is therefore independentmore » of the DR physics and is in good agreement with kinetic results.« less

Observational Study of Ion Diffusion Region tailward of the Cusp: Polar and Cluster Observations in 1998-2008

NASA Astrophysics Data System (ADS)

Muzamil, F. M.; Farrugia, C. J.; Torbert, R. B.; Argall, M. R.; Wang, S.

2015-12-01

Asymmetries in plasma density and the presence of a guide field significantly alter the structure of the ion diffusion region (IDR) in symmetric, collisionless reconnection. These features have been shown by numerical simulations under moderate density asymmetries (~10), and theoretical analyses. However, very few studies have addressed these issues with in-situ observations. We have compiled a collection of Cluster and Polar crossings of the high-latitude magnetopause poleward of the cusp under northward interplanetary magnetic field in the years 1998-2008 when signatures of reconnection inside the IDR are observed. They encompass a wide range of density asymmetries (~10 to 1000), magnetic field asymmetries (~0.2 to 0.9), and guide fields (~10 to ~60 %). In this dedicated observational study, we target the following topics: (1) The alteration of the structure of the IDR -- i.e., its width, the non-colocation of stagnation and X-lines, jet outflow speed, and biasing of the reconnection outflow jet toward the magnetosphere -- as a function of increasing density asymmetry, and (2) the diamagnetic drift of the X-line. Further, focusing on IDR crossings during plasma flow reversals and/or near-simultaneous crossings on either side of the X-line by two spacecraft under steady ambient conditions, we report on the contrast in the Hall fields and the plasma behavior on the sunward versus the tailward sides of the X-line in its dependence on the strength of the guide field.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zohar, S.; Choi, Y.; Love, D. M.

We use X-ray Excited Luminescence Microscopy to investigate the elemental and layer resolved magnetic reversal in an interlayer exchange coupled (IEC) epitaxial Fe/Cr wedge/Co heterostructure. The transition from strongly coupled parallel Co-Fe reversal for Cr thickness t(Cr) < 0.34 nm to weakly coupled layer independent reversal for t(Cr) > 1.5 nm is punctuated at 0.34 < t(Cr) < 1.5 nm by a combination of IEC guided domain wall motion and stationary zig zag domain walls. Domain walls nucleated at switching field minima are guided by IEC spatial gradients and collapse at switching field maxima.

Synthesis of Micelles Guided Magnetite (Fe3O4) Hollow Spheres and their application for AC Magnetic Field Responsive Drug Release

PubMed Central

Mandal Goswami, Madhuri

2016-01-01

This paper reports on synthesis of hollow spheres of magnetite, guided by micelles and their application in drug release by the stimulus responsive technique. Here oleyelamine micelles are used as the core substance for the formation of magnetite nano hollow spheres (NHS). Diameter and shell thickness of NHS have been changed by changing concentration of the micelles. Mechanism of NHS formation has been established by investigating the aliquot collected at different time during the synthesis of NHS. It has been observed that oleyelamine as micelles play an important role to generate hollow-sphere particles of different diameter and thickness just by varying its amount. Structural analysis was done by XRD measurement and morphological measurements, SEM and TEM were performed to confirm the shape and size of the NHS. FTIR measurement support the formation of magnetite phase too. Frequency dependent AC magnetic measurements and AC magnetic field stimulated drug release event by these particles provide a direction of the promising application of these NHS for better cancer treatment in near future. Being hollow & porous in structure and magnetic in nature, such materials will also be useful in other applications such as in removal of toxic materials, magnetic separation etc. PMID:27796329

Interplanetary Magnetic Field Guiding Relativistic Particles

NASA Technical Reports Server (NTRS)

Masson, S.; Demoulin, P.; Dasso, S.; Klein, K. L.

2011-01-01

The origin and the propagation of relativistic solar particles (0.5 to few Ge V) in the interplanetary medium remains a debated topic. These relativistic particles, detected at the Earth by neutron monitors have been previously accelerated close to the Sun and are guided by the interplanetary magnetic field (IMF) lines, connecting the acceleration site and the Earth. Usually, the nominal Parker spiral is considered for ensuring the magnetic connection to the Earth. However, in most GLEs the IMF is highly disturbed, and the active regions associated to the GLEs are not always located close to the solar footprint of the nominal Parker spiral. A possible explanation is that relativistic particles are propagating in transient magnetic structures, such as Interplanetary Coronal Mass Ejections (ICMEs). In order to check this interpretation, we studied in detail the interplanetary medium where the particles propagate for 10 GLEs of the last solar cycle. Using the magnetic field and the plasma parameter measurements (ACE/MAG and ACE/SWEPAM), we found widely different IMF configurations. In an independent approach we develop and apply an improved method of the velocity dispersion analysis to energetic protons measured by SoHO/ERNE. We determined the effective path length and the solar release time of protons from these data and also combined them with the neutron monitor data. We found that in most of the GLEs, protons propagate in transient magnetic structures. Moreover, the comparison between the interplanetary magnetic structure and the interplanetary length suggest that the timing of particle arrival at Earth is dominantly determined by the type of IMF in which high energetic particles are propagating. Finally we find that these energetic protons are not significantly scattered during their transport to Earth.

High power heating of magnetic reconnection in merging tokamak experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ono, Y.; Tanabe, H.; Gi, K.

2015-05-15

Significant ion/electron heating of magnetic reconnection up to 1.2 keV was documented in two spherical tokamak plasma merging experiment on MAST with the significantly large Reynolds number R∼10{sup 5}. Measured 1D/2D contours of ion and electron temperatures reveal clearly energy-conversion mechanisms of magnetic reconnection: huge outflow heating of ions in the downstream and localized heating of electrons at the X-point. Ions are accelerated up to the order of poloidal Alfven speed in the reconnection outflow region and are thermalized by fast shock-like density pileups formed in the downstreams, in agreement with recent solar satellite observations and PIC simulation results. The magneticmore » reconnection efficiently converts the reconnecting (poloidal) magnetic energy mostly into ion thermal energy through the outflow, causing the reconnection heating energy proportional to square of the reconnecting (poloidal) magnetic field B{sub rec}{sup 2}  ∼  B{sub p}{sup 2}. The guide toroidal field B{sub t} does not affect the bulk heating of ions and electrons, probably because the reconnection/outflow speeds are determined mostly by the external driven inflow by the help of another fast reconnection mechanism: intermittent sheet ejection. The localized electron heating at the X-point increases sharply with the guide toroidal field B{sub t}, probably because the toroidal field increases electron confinement and acceleration length along the X-line. 2D measurements of magnetic field and temperatures in the TS-3 tokamak merging experiment also reveal the detailed reconnection heating mechanisms mentioned above. The high-power heating of tokamak merging is useful not only for laboratory study of reconnection but also for economical startup and heating of tokamak plasmas. The MAST/TS-3 tokamak merging with B{sub p} > 0.4 T will enables us to heat the plasma to the alpha heating regime: T{sub i} > 5 keV without using any additional heating facility.« less

A Three-dimensional Simulation of a Magnetized Accretion Disk: Fast Funnel Accretion onto a Weakly Magnetized Star

NASA Astrophysics Data System (ADS)

Takasao, Shinsuke; Tomida, Kengo; Iwasaki, Kazunari; Suzuki, Takeru K.

2018-04-01

We present the results of a global, three-dimensional magnetohydrodynamics simulation of an accretion disk with a rotating, weakly magnetized central star. The disk is threaded by a weak, large-scale poloidal magnetic field, and the central star has no strong stellar magnetosphere initially. Our simulation investigates the structure of the accretion flows from a turbulent accretion disk onto the star. The simulation reveals that fast accretion onto the star at high latitudes occurs even without a stellar magnetosphere. We find that the failed disk wind becomes the fast, high-latitude accretion as a result of angular momentum exchange mediated by magnetic fields well above the disk, where the Lorentz force that decelerates the rotational motion of gas can be comparable to the centrifugal force. Unlike the classical magnetospheric accretion scenario, fast accretion streams are not guided by magnetic fields of the stellar magnetosphere. Nevertheless, the accretion velocity reaches the free-fall velocity at the stellar surface due to the efficient angular momentum loss at a distant place from the star. This study provides a possible explanation why Herbig Ae/Be stars whose magnetic fields are generally not strong enough to form magnetospheres also show indications of fast accretion. A magnetically driven jet is not formed from the disk in our model. The differential rotation cannot generate sufficiently strong magnetic fields for the jet acceleration because the Parker instability interrupts the field amplification.

Magnetic particle capture for biomagnetic fluid flow in stenosed aortic bifurcation considering particle-fluid coupling

NASA Astrophysics Data System (ADS)

Bose, Sayan; Banerjee, Moloy

2015-07-01

Magnetic nanoparticles drug carriers continue to attract considerable interest for drug targeting in the treatment of cancer and other pathological conditions. Guiding magnetic iron oxide nanoparticles with the help of an external magnetic field to its target is the basic principle behind the Magnetic Drug Targeting (MDT). It is essential to couple the ferrohydrodynamic (FHD) and magnetohydrodynamic (MHD) principles when magnetic fields are applied to blood as a biomagnetic fluid. The present study is devoted to study on MDT technique by particle tracking in the presence of a non uniform magnetic field in a stenosed aortic bifurcation. The present numerical model of biomagnetic fluid dynamics (BFD) takes into accounts both magnetization and electrical conductivity of blood. The blood flow in the bifurcation is considered to be incompressible and Newtonian. An Eulerian-Lagrangian technique is adopted to resolve the hemodynamic flow and the motion of the magnetic particles in the flow using ANSYS FLUENT two way particle-fluid coupling. An implantable infinitely long cylindrical current carrying conductor is used to create the requisite magnetic field. Targeted transport of the magnetic particles in a partly occluded vessel differs distinctly from the same in a regular unblocked vessel. Results concerning the velocity and temperature field indicate that the presence of the magnetic field influences the flow field considerably and the disturbances increase as the magnetic field strength increases. The insert position is also varied to observe the variation in flow as well as temperature field. Parametric investigation is conducted and the influence of the particle size (dp), flow Reynolds number (Re) and external magnetic field strength (B0) on the "capture efficiency" (CE) is reported. The difference in CE is also studied for different particle loading condition. According to the results, the magnetic field increased the particle concentration in the target region. Analysis shows that there exists an optimum regime of operating parameters for which deposition of the drug carrying magnetic particles in a target zone on the partly occluded vessel wall can be maximized. The results provide useful design bases for in vitro set up for the investigation of MDT in stenosed blood vessels.

Testing of Photomultiplier Tubes in a Magnetic Field

NASA Astrophysics Data System (ADS)

Waldron, Zachary; A1 Collaboration

2016-09-01

The A1 collaboration at MAMI in Mainz, Germany has designed a neutron detector that can be used in experiments to measure the electric form factor of the neutron. They will measure elastic scattering from the neutron, using the polarized electron beam from MAMI at A1's experimental hall. The detector will be composed of two walls of staggered scintillator bars which will be read out by photomultiplier tubes (PMT), connected to both ends of each scintillator via light guides. The experiment requires a magnetic field with strength of 1 Tesla, 2m away from the first scintillator wall. The resulting fringe field is sufficient to disrupt the PMTs, despite the addition of Mu Metal shielding. The effects of the fringe field on these PMTs was tested to optimize the amplification of the PMTs. A Helmholtz Coil was designed to generate a controlled magnetic field with equivalent strength to the field that the PMTs will encounter. The PMTs were read out using a multi-channel analyzer, were tested at various angles relative to the magnetic field in order to determine the optimal orientation to minimize signal disruption. Tests were also performed to determine: the neutron detector response to cosmic radiation; and the best method for measuring a magnetic field's strength in two dimensions. National Science Foundation Grant No. IIA-1358175.

Impact of Magnetic Draping, Convection, and Field Line Tying on Magnetopause Reconnection Under Northward IMF

NASA Technical Reports Server (NTRS)

Wendel, Deirdre E.; Reiff, Patricia H.; Goldstein, Melvyn L.

2010-01-01

We simulate a northward IMF cusp reconnection event at the magnetopause using the OpenGGCM resistive MHD code. The ACE input data, solar wind parameters, and dipole tilt belong to a 2002 reconnection event observed by IMAGE and Cluster. Based on a fully three-dimensional skeleton separators, nulls, and parallel electric fields, we show magnetic draping, convection, ionospheric field line tying play a role in producing a series of locally reconnecting nulls with flux ropes. The flux ropes in the cusp along the global separator line of symmetry. In 2D projection, the flux ropes the appearance of a tearing mode with a series of 'x's' and 'o's' but bearing a kind of 'guide field' that exists only within the magnetopause. The reconnecting field lines in the string of ropes involve IMF and both open and closed Earth magnetic field lines. The observed magnetic geometry reproduces the findings of a superposed epoch impact parameter study derived from the Cluster magnetometer data for the same event. The observed geometry has repercussions for spacecraft observations of cusp reconnection and for the imposed boundary conditions reconnection simulations.

Role of atomic spin-mechanical coupling in the problem of a magnetic biocompass

NASA Astrophysics Data System (ADS)

Cao, Yunshan; Yan, Peng

2018-04-01

It is a well established notion that animals can detect the Earth's magnetic field, while the biophysical origin of such magnetoreception is still elusive. Recently, a magnetic receptor Drosophila CG8198 (MagR) with a rodlike protein complex is reported [S. Qin et al., Nat. Mater. 15, 217 (2016), 10.1038/nmat4484] to act like a compass needle to guide the magnetic orientation of animals. This view, however, is challenged [M. Meister, Elife 5, e17210 (2016), 10.7554/eLife.17210] by arguing that thermal fluctuations beat the Zeeman coupling of the proteins's magnetic moment with the rather weak geomagnetic field (˜25 -65 μ T ). In this work, we show that the spin-mechanical interaction at the atomic scale gives rise to a high blocking temperature which allows a good alignment of the protein's magnetic moment with the Earth's magnetic field at room temperature. Our results provide a promising route to resolve the debate on the thermal behaviors of MagR, and may stimulate a broad interest in spin-mechanical couplings down to atomistic levels.

Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) ablation of liver tumours.

PubMed

Wijlemans, J W; Bartels, L W; Deckers, R; Ries, M; Mali, W P Th M; Moonen, C T W; van den Bosch, M A A J

2012-09-28

Recent decades have seen a paradigm shift in the treatment of liver tumours from invasive surgical procedures to minimally invasive image-guided ablation techniques. Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) is a novel, completely non-invasive ablation technique that has the potential to change the field of liver tumour ablation. The image guidance, using MR imaging and MR temperature mapping, provides excellent planning images and real-time temperature information during the ablation procedure. However, before clinical implementation of MR-HIFU for liver tumour ablation is feasible, several organ-specific challenges have to be addressed. In this review we discuss the MR-HIFU ablation technique, the liver-specific challenges for MR-HIFU tumour ablation, and the proposed solutions for clinical translation.

Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) ablation of liver tumours

PubMed Central

Bartels, L.W.; Deckers, R.; Ries, M.; Mali, W.P.Th.M.; Moonen, C.T.W.; van den Bosch, M.A.A.J.

2012-01-01

Abstract Recent decades have seen a paradigm shift in the treatment of liver tumours from invasive surgical procedures to minimally invasive image-guided ablation techniques. Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) is a novel, completely non-invasive ablation technique that has the potential to change the field of liver tumour ablation. The image guidance, using MR imaging and MR temperature mapping, provides excellent planning images and real-time temperature information during the ablation procedure. However, before clinical implementation of MR-HIFU for liver tumour ablation is feasible, several organ-specific challenges have to be addressed. In this review we discuss the MR-HIFU ablation technique, the liver-specific challenges for MR-HIFU tumour ablation, and the proposed solutions for clinical translation. PMID:23022541

Enhancement of 3D guide field magnetic reconnection by self-generated kinetic turbulence

NASA Astrophysics Data System (ADS)

Alejandro Munoz Sepulveda, Patricio; Buechner, Joerg

2017-04-01

Kinetic plasma turbulence is ubiquitous in magnetic reconnection in laboratory, space and astrophysical plasmas. Most of previous investigations focused on the role of low-frequency/Alfvénic turbulence in homogeneous plasmas. High-frequency/electron-scale turbulence in the reconnecting current sheets, however, have been rarely addressed. Our aim is to investigate the role of this self-generated turbulence via kinetic instabilities in 3D magnetic reconnection. For this sake, we carried out 3D fully-kinetic Particle-in-Cell (PiC) code numerical simulations of force free current sheets with a guide magnetic field, a common situation in the plasmas of interest. We show that the dynamically evolving kinetic turbulence spectra is broadband, with a power-law spectrum between the lower hybrid and up to the electron frequencies with a spectral index near 2.7 at the reconnection site. This result is directly in the frequency-domain, without change of frame of reference assuming Taylor's hypothesis. The evolution of the turbulence correlates with the growth and rate of magnetic reconnection and can be explained by unstable waves caused by (kinetic) streaming instabilities driven by electron current. This provides a plausible explanation for the enhancement of magnetic reconnection due to turbulence observed in laboratory experiments like MRX, VTF and VINETA-II, as well as of in-situ measurements in the Earth's magnetosphere by the MMS spacecraft.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rubinstein, A; Tailor, R; Melancon, A

Purpose: To simulate and measure magnetic-field-induced radiation dose effects in a mouse lung phantom. This data will be used to support pre-clinical experiments related to MRI-guided radiation therapy systems. Methods: A mouse lung phantom was constructed out of 1.5×1.5×2.0-cm{sup 3} lung-equivalent material (0.3 g/cm{sup 3}) surrounded by a 0.6-cm solid water shell. EBT3 film was inserted into the phantom and the phantom was placed between the poles of an H-frame electromagnet. The phantom was irradiated with a cobalt-60 beam (1.25 MeV) with the electromagnet set to various magnetic field strengths (0T, 0.35T, 0.9T, and 1.5T). These magnetic field strengths correspondmore » to the range of field strengths seen in MRI-guided radiation therapy systems. Dose increases at the solid-water-to-lung-interface and dose decreases at the lung-to-solid-water interface were compared with results of Monte Carlo simulations performed with MCNP6. Results: The measured dose to lung at the solid-water-to-lung interface increased by 0%, 16%, and 29% with application of the 0.35T, 0.9T, and 1.5T magnetic fields, respectively. The dose to lung at the lung-to-solid-water interface decreased by 4%, 18%, and 24% with application of the 0.35T, 0.9T, and 1.5T magnetic fields, respectively. Monte Carlo simulations showed dose increases of 0%, 16%, and 31% and dose decreases of 4%, 16%, and 25%. Conclusion: Only small dose perturbations were observed at the lung-solid-water interfaces for the 0.35T case, while more substantial dose perturbations were observed for the 0.9T and 1.5T cases. There is good agreement between the Monte Carlo calculations and the experimental measurements (within 2%). These measurements will aid in designing pre-clinical studies which investigate the potential biological effects of radiation therapy in the presence of a strong magnetic field. This work was partially funded by Elekta.« less

Magnetospheric Multiscale Observations of Magnetic Reconnection Associated with Kelvin-Helmholtz Waves

NASA Technical Reports Server (NTRS)

Eriksson, S.; Lavraud, B.; Wilder, F. D.; Stawarz, J. E.; Giles, B. L.; Burch, J. L.; Baumjohann, W.; Ergun, R. E.; Lindqvist, P.-A.; Magnes, W.;

Electron guns and collectors developed at INP for electron cooling devices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharapa, A.N.; Shemyakin, A.V.

1997-09-01

Institute of Nuclear Physics (INP) has a rich experience in designing electron guns and collectors for electron cooling devices. This paper is a review of the experience of several INP research groups in this field. Some results obtained at INP for systems without a guiding magnetic field are also discussed.

Intraoperative high-field magnetic resonance imaging, multimodal neuronavigation, and intraoperative electrophysiological monitoring-guided surgery for treating supratentorial cavernomas.

PubMed

Li, Fang-Ye; Chen, Xiao-Lei; Xu, Bai-Nan

2016-09-01

To determine the beneficial effects of intraoperative high-field magnetic resonance imaging (MRI), multimodal neuronavigation, and intraoperative electrophysiological monitoring-guided surgery for treating supratentorial cavernomas. Twelve patients with 13 supratentorial cavernomas were prospectively enrolled and operated while using a 1.5 T intraoperative MRI, multimodal neuronavigation, and intraoperative electrophysiological monitoring. All cavernomas were deeply located in subcortical areas or involved critical areas. Intraoperative high-field MRIs were obtained for the intraoperative "visualization" of surrounding eloquent structures, "brain shift" corrections, and navigational plan updates. All cavernomas were successfully resected with guidance from intraoperative MRI, multimodal neuronavigation, and intraoperative electrophysiological monitoring. In 5 cases with supratentorial cavernomas, intraoperative "brain shift" severely deterred locating of the lesions; however, intraoperative MRI facilitated precise locating of these lesions. During long-term (>3 months) follow-up, some or all presenting signs and symptoms improved or resolved in 4 cases, but were unchanged in 7 patients. Intraoperative high-field MRI, multimodal neuronavigation, and intraoperative electrophysiological monitoring are helpful in surgeries for the treatment of small deeply seated subcortical cavernomas.

Development of Turbulent Magnetic Reconnection in a Magnetic Island

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Can; Lu, Quanming; Wang, Rongsheng

In this paper, with two-dimensional particle-in-cell simulations, we report that the electron Kelvin–Helmholtz instability is unstable in the current layer associated with a large-scale magnetic island, which is formed in multiple X-line guide field reconnections. The current sheet is fragmented into many small current sheets with widths down to the order of the electron inertial length. Secondary magnetic reconnection then occurs in these fragmented current sheets, which leads to a turbulent state. The electrons are highly energized in such a process.

Spin-flop and magnetodielectric reversal in Yb substituted GdMnO3

NASA Astrophysics Data System (ADS)

Pal, A.; Prellier, W.; Murugavel, P.

2018-03-01

The evolution of various spin structures in Yb doped GdMnO3 distorted orthorhombic perovskite system was investigated from their magnetic, dielectric and magnetodielectric characteristics. The Gd1-x Yb x MnO3 (0  ⩽  x  ⩽  0.15) revealed an enhanced magnetodielectric coupling when their magnetic structure is guided from ab to the bc-cycloidal spin structure upon Yb doping. The compounds exhibit magnetic field and temperature controlled spin-flop from c to a-axis. Additionally, magnetodielectric reversal is observed for the x  =  0.1 sample which depends on both magnetic field and temperature. The resultant correlation between magnetic and electric orderings is discussed in the frame of symmetric and antisymmetric exchange interaction models. These findings provide further insight in understanding the magnetoelectric materials and importantly show a way to tune the magnetic and magnetodielectric properties towards better application potential.

Hamiltonian theory of guiding-center motion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Littlejohn, R.G.

1980-05-01

A Hamiltonian treatment of the guiding center problem is given which employs noncanonical coordinates in phase space. Separation of the unperturbed system from the perturbation is achieved by using a coordinate transformation suggested by a theorem of Darboux. As a model to illustrate the method, motion in the magnetic field B=B(x,y)z is studied. Lie transforms are used to carry out the perturbation expansion.

Remote magnetic actuation using a clinical scale system

PubMed Central

Stehning, Christian; Gleich, Bernhard

2018-01-01

Remote magnetic manipulation is a powerful technique for controlling devices inside the human body. It enables actuation and locomotion of tethered and untethered objects without the need for a local power supply. In clinical applications, it is used for active steering of catheters in medical interventions such as cardiac ablation for arrhythmia treatment and for steering of camera pills in the gastro-intestinal tract for diagnostic video acquisition. For these applications, specialized clinical-scale field applicators have been developed, which are rather limited in terms of field strength and flexibility of field application. For a general-purpose field applicator, flexible field generation is required at high field strengths as well as high field gradients to enable the generation of both torques and forces on magnetic devices. To date, this requirement has only been met by small-scale experimental systems. We have built a highly versatile clinical-scale field applicator that enables the generation of strong magnetic fields as well as strong field gradients over a large workspace. We demonstrate the capabilities of this coil-based system by remote steering of magnetic drills through gel and tissue samples with high torques on well-defined curved trajectories. We also give initial proof that, when equipped with high frequency transmit-receive coils, the machine is capable of real-time magnetic particle imaging while retaining a clinical-scale bore size. Our findings open the door for image-guided radiation-free remote magnetic control of devices at the clinical scale, which may be useful in minimally invasive diagnostic and therapeutic medical interventions. PMID:29494647

Circularly polarized attosecond pulse generation and applications to ultrafast magnetism

NASA Astrophysics Data System (ADS)

Bandrauk, André D.; Guo, Jing; Yuan, Kai-Jun

2017-12-01

Attosecond science is a growing new field of research and potential applications which relies on the development of attosecond light sources. Achievements in the generation and application of attosecond pulses enable to investigate electron dynamics in the nonlinear nonperturbative regime of laser-matter interactions on the electron’s natural time scale, the attosecond. In this review, we describe the generation of circularly polarized attosecond pulses and their applications to induce attosecond magnetic fields, new tools for ultrafast magnetism. Simulations are performed on aligned one-electron molecular ions by using nonperturbative nonlinear solutions of the time-dependent Schrödinger equation. We discuss how bichromatic circularly polarized laser pulses with co-rotating or counter-rotating components induce electron-parent ion recollisions, thus producing circularly polarized high-order harmonic generation, the source of circularly polarized attosecond pulses. Ultrafast quantum electron currents created by the generated attosecond pulses give rise to attosecond magnetic field pulses. The results provide a guiding principle for producing circularly polarized attosecond pulses and ultrafast magnetic fields in complex molecular systems for future research in ultrafast magneto-optics.

A Comprehensive Comparison of Relativistic Particle Integrators

NASA Astrophysics Data System (ADS)

Ripperda, B.; Bacchini, F.; Teunissen, J.; Xia, C.; Porth, O.; Sironi, L.; Lapenta, G.; Keppens, R.

2018-03-01

We compare relativistic particle integrators commonly used in plasma physics, showing several test cases relevant for astrophysics. Three explicit particle pushers are considered, namely, the Boris, Vay, and Higuera–Cary schemes. We also present a new relativistic fully implicit particle integrator that is energy conserving. Furthermore, a method based on the relativistic guiding center approximation is included. The algorithms are described such that they can be readily implemented in magnetohydrodynamics codes or Particle-in-Cell codes. Our comparison focuses on the strengths and key features of the particle integrators. We test the conservation of invariants of motion and the accuracy of particle drift dynamics in highly relativistic, mildly relativistic, and non-relativistic settings. The methods are compared in idealized test cases, i.e., without considering feedback onto the electrodynamic fields, collisions, pair creation, or radiation. The test cases include uniform electric and magnetic fields, {\\boldsymbol{E}}× {\\boldsymbol{B}} fields, force-free fields, and setups relevant for high-energy astrophysics, e.g., a magnetic mirror, a magnetic dipole, and a magnetic null. These tests have direct relevance for particle acceleration in shocks and in magnetic reconnection.

A novel electron accelerator for MRI-Linac radiotherapy.

PubMed

Whelan, Brendan; Gierman, Stephen; Holloway, Lois; Schmerge, John; Keall, Paul; Fahrig, Rebecca

2016-03-01

MRI guided radiotherapy is a rapidly growing field; however, current electron accelerators are not designed to operate in the magnetic fringe fields of MRI scanners. As such, current MRI-Linac systems require magnetic shielding, which can degrade MR image quality and limit system flexibility. The purpose of this work was to develop and test a novel medical electron accelerator concept which is inherently robust to operation within magnetic fields for in-line MRI-Linac systems. Computational simulations were utilized to model the accelerator, including the thermionic emission process, the electromagnetic fields within the accelerating structure, and resulting particle trajectories through these fields. The spatial and energy characteristics of the electron beam were quantified at the accelerator target and compared to published data for conventional accelerators. The model was then coupled to the fields from a simulated 1 T superconducting magnet and solved for cathode to isocenter distances between 1.0 and 2.4 m; the impact on the electron beam was quantified. For the zero field solution, the average current at the target was 146.3 mA, with a median energy of 5.8 MeV (interquartile spread of 0.1 MeV), and a spot size diameter of 1.5 mm full-width-tenth-maximum. Such an electron beam is suitable for therapy, comparing favorably to published data for conventional systems. The simulated accelerator showed increased robustness to operation in in-line magnetic fields, with a maximum current loss of 3% compared to 85% for a conventional system in the same magnetic fields. Computational simulations suggest that replacing conventional DC electron sources with a RF based source could be used to develop medical electron accelerators which are robust to operation in in-line magnetic fields. This would enable the development of MRI-Linac systems with no magnetic shielding around the Linac and reduce the requirements for optimization of magnetic fringe field, simplify design of the high-field magnet, and increase system flexibility.

A novel electron accelerator for MRI-Linac radiotherapy

PubMed Central

Whelan, Brendan; Gierman, Stephen; Holloway, Lois; Schmerge, John; Keall, Paul; Fahrig, Rebecca

2016-01-01

Purpose: MRI guided radiotherapy is a rapidly growing field; however, current electron accelerators are not designed to operate in the magnetic fringe fields of MRI scanners. As such, current MRI-Linac systems require magnetic shielding, which can degrade MR image quality and limit system flexibility. The purpose of this work was to develop and test a novel medical electron accelerator concept which is inherently robust to operation within magnetic fields for in-line MRI-Linac systems. Methods: Computational simulations were utilized to model the accelerator, including the thermionic emission process, the electromagnetic fields within the accelerating structure, and resulting particle trajectories through these fields. The spatial and energy characteristics of the electron beam were quantified at the accelerator target and compared to published data for conventional accelerators. The model was then coupled to the fields from a simulated 1 T superconducting magnet and solved for cathode to isocenter distances between 1.0 and 2.4 m; the impact on the electron beam was quantified. Results: For the zero field solution, the average current at the target was 146.3 mA, with a median energy of 5.8 MeV (interquartile spread of 0.1 MeV), and a spot size diameter of 1.5 mm full-width-tenth-maximum. Such an electron beam is suitable for therapy, comparing favorably to published data for conventional systems. The simulated accelerator showed increased robustness to operation in in-line magnetic fields, with a maximum current loss of 3% compared to 85% for a conventional system in the same magnetic fields. Conclusions: Computational simulations suggest that replacing conventional DC electron sources with a RF based source could be used to develop medical electron accelerators which are robust to operation in in-line magnetic fields. This would enable the development of MRI-Linac systems with no magnetic shielding around the Linac and reduce the requirements for optimization of magnetic fringe field, simplify design of the high-field magnet, and increase system flexibility. PMID:26936713

Exact image theory for the problem of dielectric/magnetic slab

NASA Technical Reports Server (NTRS)

Lindell, I. V.

1987-01-01

Exact image method, recently introduced for the exact solution of electromagnetic field problems involving homogeneous half spaces and microstrip-like geometries, is developed for the problem of homogeneous slab of dielectric and/or magnetic material in free space. Expressions for image sources, creating the exact reflected and transmitted fields, are given and their numerical evaluation is demonstrated. Nonradiating modes, guided by the slab and responsible for the loss of convergence of the image functions, are considered and extracted. The theory allows, for example, an analysis of finite ground planes in microstrip antenna structures.

Positive and negative effective mass of classical particles in oscillatory and static fields.

PubMed

Dodin, I Y; Fisch, N J

2008-03-01

A classical particle oscillating in an arbitrary high-frequency or static field effectively exhibits a modified rest mass m(eff) derived from the particle averaged Lagrangian. Relativistic ponderomotive and diamagnetic forces, as well as magnetic drifts, are obtained from the m(eff) dependence on the guiding center location and velocity. The effective mass is not necessarily positive and can result in backward acceleration when an additional perturbation force is applied. As an example, adiabatic dynamics with m||>0 and m||<0 is demonstrated for a wave-driven particle along a dc magnetic field, m|| being the effective longitudinal mass derived from m(eff). Multiple energy states are realized in this case, yielding up to three branches of m|| for a given magnetic moment and parallel velocity.

Summary of the Madison Dynamo Experiment

NASA Astrophysics Data System (ADS)

Kendrick, R. D.; Spence, E. J.; Nornberg, M. D.; Forest, C. B.

2001-10-01

A spherical dynamo experiment has been constructed at the University of Wisconsin's liquid sodium facility. The goals of the experiment are to observe and understand magnetic instabilities driven by flow shear in MHD systems, investigate MHD turbulence for magnetic Reynolds numbers of ~100, and understand the role of fluid turbulence in current generation. Magnetic field generation is possible for only specific flow geometries. We have studied and achieved simple roll flow geometries in a full scale water experiment. Results from this experiment have guided the design of the sodium experiment. The experiment consists of a 1 m diameter, spherical stainless steel vessel filled with liquid sodium at 110 Celsius. Two 100 Hp motors with impellers drive flows in the liquid sodium with flow velocities ~ 15 m/s. A gaussian grid of Hall probes on the surface of the sodium vessel measure the generated external magnetic field. Hall probe feed-thru arrays measure the internal field. Preliminary investigations include measurements of the turbulent electromotive force and excitation of magnetic eigenmodes.

Design of the Madison Dynamo Experiment

NASA Astrophysics Data System (ADS)

Kendrick, R. D.; Bayliss, R. A.; Forest, C. B.; Nornberg, M. D.; O'Connell, R.; Spence, E. J.

2003-10-01

A spherical dynamo experiment has been constructed at the University of Wisconsin's liquid sodium facility. The goals of the experiment are to observe and understand magnetic instabilities driven by flow shear in MHD systems, investigate MHD turbulence for magnetic Reynolds numbers of ˜100, and understand the role of fluid turbulence in current generation. Magnetic field generation is possible for only specific flow geometries. We have studied and achieved simple roll flow geometries in a full scale water experiment. Results from this experiment have guided the design of the sodium experiment. The experiment consists of a 1 m diameter, spherical stainless steel vessel filled with liquid sodium at 110 Celsius. Two 100 Hp motors with impellers drive flows in the liquid sodium with flow velocities ˜ 15 m/s. A grid of Hall probes on the surface of the sodium vessel measure the generated external magnetic field. Hall probe feed-thru arrays measure the internal field. Preliminary investigations include measurements of the turbulent electromotive force and excitation of magnetic eigenmodes.

Static magnetic susceptibility of radiopaque NiTiPt and NiTiEr

NASA Astrophysics Data System (ADS)

Chovan, Drahomír; Gandhi, Abbasi; Butler, James; Tofail, Syed A. M.

2018-04-01

Magnetic properties of metallic alloys used in biomedical industry are important for the magnetic resonance imaging (MRI). If the alloys were to be used for long term implants or as guiding devices, safety of the patient as well as the medical staff has to be ensured. Strong response to the external magnetic field can cause mechanical damage to the patients body. In this paper we present magnetic susceptibility of nickel rich, ternary NiTiPt and NiTiEr to static magnetic field. We show that the magnetic susceptibility of these radiopaque alloys has values in low paramagnetic region comparable to the binary nickel-titanium. Furthermore, we studied the effect of the thermal and mechanical treatments on magnetic properties. Despite deviation from linear M (H) treated samples spanning small region around H = 0 , the linearity of the M (H) and χ =d M /d H values suggest that these ternary alloys are safe to use under MRI conditions.

Trapped particles at a magnetic discontinuity

NASA Technical Reports Server (NTRS)

Stern, D. P.

1972-01-01

At a tangential discontinuity between two constant magnetic fields a layer of trapped particles can exist, this work examines the conditions under which the current carried by such particles tends to maintain the discontinuity. Three cases are examined. If the discontinuity separates aligned vacuum fields, the only requirement is that they be antiparallel. With arbitrary relative orientations, the field must have equal intensities on both sides. Finally, with a guiding center plasma on both sides, the condition reduces to a relation which is also derivable from hydromagnetic theory. Arguments are presented for the occurrence of such trapped modes in the magnetopause and for the non-existence of specular particle reflection.

Reduction of magnetic field fluctuations in powered magnets for NMR using inductive measurements and sampled-data feedback control.

PubMed

Li, Mingzhou; Schiano, Jeffrey L; Samra, Jenna E; Shetty, Kiran K; Brey, William W

2011-10-01

Resistive and hybrid (resistive/superconducting) magnets provide substantially higher magnetic fields than those available in low-temperature superconducting magnets, but their relatively low spatial homogeneity and temporal field fluctuations are unacceptable for high resolution NMR. While several techniques for reducing temporal fluctuations have demonstrated varying degrees of success, this paper restricts attention to methods that utilize inductive measurements and feedback control to actively cancel the temporal fluctuations. In comparison to earlier studies using analog proportional control, this paper shows that shaping the controller frequency response results in significantly higher reductions in temporal fluctuations. Measurements of temporal fluctuation spectra and the frequency response of the instrumentation that cancels the temporal fluctuations guide the controller design. In particular, we describe a sampled-data phase-lead-lag controller that utilizes the internal model principle to selectively attenuate magnetic field fluctuations caused by the power supply ripple. We present a quantitative comparison of the attenuation in temporal fluctuations afforded by the new design and a proportional control design. Metrics for comparison include measurements of the temporal fluctuations using Faraday induction and observations of the effect that the fluctuations have on nuclear resonance measurements. Copyright © 2011. Published by Elsevier Inc.

Attainment of students’ conception in magnetic fields by using of direct observation and symbolic language ability

NASA Astrophysics Data System (ADS)

Desy Fatmaryanti, Siska; Suparmi; Sarwanto; Ashadi

2017-11-01

This study focuses on description attainment of students’ conception in the magnetic field. The conception was based by using of direct observation and symbolic language ability. The method used is descriptive quantitative research. The subject of study was about 86 students from 3 senior high school at Purworejo. The learning process was done by guided inquiry model. During the learning, students were required to actively investigate the concept of a magnetic field around a straight wire electrical current Data retrieval was performed using an instrument in the form of a multiple choice test reasoned and observation during the learning process. There was four indicator of direct observation ability and four indicators of symbolic language ability to grouping category of students conception. The results of average score showed that students conception about the magnitude more better than the direction of magnetic fields in view of symbolic language. From the observation, we found that students could draw the magnetic fields line not from a text book but their direct observation results. They used various way to get a good accuracy of observation results. Explicit recommendations are presented in the discussion section at the end of this paper.

Active galaxies. A strong magnetic field in the jet base of a supermassive black hole.

PubMed

Martí-Vidal, Ivan; Muller, Sébastien; Vlemmings, Wouter; Horellou, Cathy; Aalto, Susanne

2015-04-17

Active galactic nuclei (AGN) host some of the most energetic phenomena in the universe. AGN are thought to be powered by accretion of matter onto a rotating disk that surrounds a supermassive black hole. Jet streams can be boosted in energy near the event horizon of the black hole and then flow outward along the rotation axis of the disk. The mechanism that forms such a jet and guides it over scales from a few light-days up to millions of light-years remains uncertain, but magnetic fields are thought to play a critical role. Using the Atacama Large Millimeter/submillimeter Array (ALMA), we have detected a polarization signal (Faraday rotation) related to the strong magnetic field at the jet base of a distant AGN, PKS 1830-211. The amount of Faraday rotation (rotation measure) is proportional to the integral of the magnetic field strength along the line of sight times the density of electrons. The high rotation measures derived suggest magnetic fields of at least tens of Gauss (and possibly considerably higher) on scales of the order of light-days (0.01 parsec) from the black hole. Copyright © 2015, American Association for the Advancement of Science.

Magnetospheric Multiscale Observations of an Ion Diffusion Region With Large Guide Field at the Magnetopause: Current System, Electron Heating, and Plasma Waves

NASA Astrophysics Data System (ADS)

Zhou, M.; Berchem, J.; Walker, R. J.; El-Alaoui, M.; Goldstein, M. L.; Lapenta, G.; Deng, X.; Li, J.; Le Contel, O.; Graham, D. B.; Lavraud, B.; Paterson, W. R.; Giles, B. L.; Burch, J. L.; Torbert, R. B.; Russell, C. T.; Strangeway, R. J.; Zhao, C.; Ergun, R. E.; Lindqvist, P.-A.; Marklund, G.

2018-03-01

We report Magnetospheric Multiscale (MMS) observations of a reconnecting current sheet in the presence of a weak density asymmetry with large guide field at the dayside magnetopause. An ion diffusion region (IDR) was detected associated with this current sheet. Parallel current dominated over the perpendicular current in the IDR, as found in previous studies of component reconnection. Electrons were preferentially heated parallel to the magnetic field within the IDR. The heating was manifested as a flattop distribution below 400 eV. Two types of electromagnetic electron whistler waves were observed within the regions where electrons were heated. One type of whistler wave was associated with nonlinear structures in E|| with amplitudes up to 20 mV/m. The other type was not associated with any structures in E||. Poynting fluxes of these two types of whistler waves were directed away from the X-line. We suggest that the nonlinear evolution of the oblique whistler waves gave rise to the solitary structures in E||. There was a perpendicular super-Alfvénic outflow jet that was carried by magnetized electrons. Intense electrostatic lower hybrid drift waves were localized in the current sheet center and were probably driven by the super-Alfvénic electron jet, the velocity of which was approximately equal to the diamagnetic drift of demagnetized ions. Our observations suggest that the guide field significantly modified the structures (Hall electromagnetic fields and current system) and wave properties in the IDR.

The role of fluid compression in energy conversion and particle energization during magnetic reconnection

NASA Astrophysics Data System (ADS)

Li, X.; Guo, F.; Li, G.; Li, H.

2016-12-01

Theories of particle transport and acceleration have shown that fluid compression is the leading mechanism for particle acceleration and plasma energization. However, the role of compression in particle acceleration during magnetic reconnection is unclear. We use two approaches to study this issue. First, using fully kinetic simulations, we quantitatively calculate the effect of compression in energy conversion and particle energization during magnetic reconnection for a range of plasma beta and guide field. We show that compression has an important contribution for the energy conversion between the bulk kinetic energy and the internal energy when the guide field is smaller than the reconnecting component. Based on this result, we then study the large-scale reconnection acceleration by solving the Parker's transport equation in a background reconnecting flow provided by MHD simulations. Due to the compression effect, the simulations suggest fast particle acceleration to high energies in the reconnection layer. This study clarifies the nature of particle acceleration in reconnection layer, and may be important to understand particle acceleration and plasma energization during solar flares.

The Upgrade of the Neutron Induced Positron Source NEPOMUC

NASA Astrophysics Data System (ADS)

Hugenschmidt, C.; Ceeh, H.; Gigl, T.; Lippert, F.; Piochacz, C.; Pikart, P.; Reiner, M.; Weber, J.; Zimnik, S.

2013-06-01

In summer 2012, the new NEutron induced POsitron Source MUniCh (NEPOMUC) was installed and put into operation at the research reactor FRM II. At NEPOMUC upgrade 80% 113Cd enriched Cd is used as neutron-gamma converter in order to ensure an operation time of 25 years. A structure of Pt foils inside the beam tube generates positrons by pair production. Moderated positrons leaving the Pt front foil are electrically extracted and magnetically guided to the outside of the reactor pool. The whole design, including Pt-foils, the electric lenses and the magnetic fields, has been improved in order to enhance both the intensity and the brightness of the positron beam. After adjusting the potentials and the magnetic guide and compensation fields an intensity of about 3·109 moderated positrons per second is expected. During the first start-up, the measured temperatures of about 90°C ensure a reliable operation of the positron source. Within this contribution the features and the status of NEPOMUC upgrade are elucidated. In addition, an overview of recent positron beam experiments and current developments at the spectrometers is given.

Intermittent magnetic reconnection in TS-3 merging experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ono, Y.; Hayashi, Y.; Ii, T.

2011-11-15

Ejection of current sheet with plasma mass causes impulsive and intermittent magnetic reconnection in the TS-3 spherical tokamak (ST) merging experiment. Under high guide toroidal field, the sheet resistivity is almost classical due to the sheet thickness much longer than the ion gyroradius. Large inflow flux and low current-sheet resistivity result in flux and plasma pileup followed by rapid growth of the current sheet. When the pileup exceeds a critical limit, the sheet is ejected mechanically from the squeezed X-point area. The reconnection (outflow) speed is slow during the flux/plasma pileup and is fast during the ejection, suggesting that intermittentmore » reconnection similar to the solar flare increases the averaged reconnection speed. These transient effects enable the merging tokamaks to have the fast reconnection as well as the high-power reconnection heating, even when their current-sheet resistivity is low under high guide field.« less

Adiabatic particle motion in a nearly drift-free magnetic field: Application to the geomagnetic tail

NASA Technical Reports Server (NTRS)

Stern, D. P.

1977-01-01

The guiding center motion of particles in a nearly drift free magnetic field is analyzed in order to investigate the dependence of mean drift velocity on equatorial pitch angle, the variation of local drift velocity along the trajectory, and other properties. The mean drift for adiabatic particles is expressed by means of elliptic integrals. Approximations to the twice-averaged Hamiltonian W near z = O are derived, permitting simple representation of drift paths if an electric potential also exists. In addition, the use of W or of expressions for the longitudinal invariant allows the derivation of the twice averaged Liouville equation and of the corresponding Vlasov equation. Bounce times are calculated (using the drift-free approximation), as are instantaneous guiding center drift velocities, which are then used to provide a numerical check on the formulas for the mean drift.

The role of three-dimensional transport in driving enhanced electron acceleration during magnetic reconnection

NASA Astrophysics Data System (ADS)

Swisdak, M.; Dahlin, J. T.; Drake, J. F.

2017-12-01

Magnetic reconnection is an important driver of energetic particles in many space and astrophysical phenomena. Using kinetic particle-in-cell simulations, we explore the effects that the dynamics in three-dimensions has on reconnection and the efficiency of particle acceleration. In two-dimensional systems, Alfvenic outflows expel energetic electrons into flux ropes where they become trapped and disconnected from acceleration regions. However, in three-dimensional systems these flux ropes develop axial structure that enables particles to leak out and return to acceleration regions. This requires a finite guide field so that particles may move quickly along the flux rope axis. The greatest energetic electron production occurs when the guide field is of the same order as the reconnecting component: large enough to facilitate strong transport, but not so large as to throttle the dominant Fermi mechanism responsible for efficient electron acceleration.

Diffusion of test particles in stochastic magnetic fields for small Kubo numbers.

PubMed

Neuer, Marcus; Spatschek, Karl H

2006-02-01

Motion of charged particles in a collisional plasma with stochastic magnetic field lines is investigated on the basis of the so-called A-Langevin equation. Compared to the previously used A-Langevin model, here finite Larmor radius effects are taken into account. The A-Langevin equation is solved under the assumption that the Lagrangian correlation function for the magnetic field fluctuations is related to the Eulerian correlation function (in Gaussian form) via the Corrsin approximation. The latter is justified for small Kubo numbers. The velocity correlation function, being averaged with respect to the stochastic variables including collisions, leads to an implicit differential equation for the mean square displacement. From the latter, different transport regimes, including the well-known Rechester-Rosenbluth diffusion coefficient, are derived. Finite Larmor radius contributions show a decrease of the diffusion coefficient compared to the guiding center limit. The case of small (or vanishing) mean fields is also discussed.

Magnetic field extraction of trap-based electron beams using a high-permeability grid

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hurst, N. C.; Danielson, J. R.; Surko, C. M., E-mail: csurko@physics.ucsd.edu

2015-07-15

A method to form high quality electrostatically guided lepton beams is explored. Test electron beams are extracted from tailored plasmas confined in a Penning-Malmberg trap. The particles are then extracted from the confining axial magnetic field by passing them through a high magnetic permeability grid with radial tines (a so-called “magnetic spider”). An Einzel lens is used to focus and analyze the beam properties. Numerical simulations are used to model non-adiabatic effects due to the spider, and the predictions are compared with the experimental results. Improvements in beam quality are discussed relative to the use of a hole in amore » high permeability shield (i.e., in lieu of the spider), and areas for further improvement are described.« less

Tunable Snell's law for spin waves in heterochiral magnetic films

NASA Astrophysics Data System (ADS)

Mulkers, Jeroen; Van Waeyenberge, Bartel; Milošević, Milorad V.

2018-03-01

Thin ferromagnetic films with an interfacially induced DMI exhibit nontrivial asymmetric dispersion relations that lead to unique and useful magnonic properties. Here we derive an analytical expression for the magnon propagation angle within the micromagnetic framework and show how the dispersion relation can be approximated with a comprehensible geometrical interpretation in the k space of the propagation of spin waves. We further explore the refraction of spin waves at DMI interfaces in heterochiral magnetic films, after deriving a generalized Snell's law tunable by an in-plane magnetic field, that yields analytical expressions for critical incident angles. The found asymmetric Brewster angles at interfaces of regions with different DMI strengths, adjustable by magnetic field, support the conclusion that heterochiral ferromagnetic structures are an ideal platform for versatile spin-wave guides.

Colliding or co-rotating ion beams in storage rings for EDM search

NASA Astrophysics Data System (ADS)

Koop, I. A.

2015-11-01

A new approach to search for and measure the electric dipole moment (EDM) of the proton, deuteron and some other light nuclei is presented. The idea of the method is to store two ion beams, circulating with different velocities, in a storage ring with crossed electric and magnetic guiding fields. One beam is polarized and its EDM is measured using the so-called ‘frozen spin’ method. The second beam, which is unpolarized, is used as a co-magnetometer, sensitive to the radial component of the ring’s magnetic field. The particle’s magnetic dipole moment (MDM) couples to the radial magnetic field and mimics the EDM signal. Measuring the relative vertical orbit separation of the two beams, caused by the presence of the radial magnetic field, one can control the unwanted MDM spin precession. Examples of the parameters for EDM storage rings for protons and other species of ions are presented. The use of crossed electric and magnetic fields helps to reduce the size of the ring by a factor of 10-20. We show that the bending radius of such an EDM storage ring could be about 2-3 m. Finally, a new method of increasing the spin coherence time, the so-called ‘spin wheel’, is proposed and its applicability to the EDM search is discussed.

Consistency evaluation between EGSnrc and Geant4 charged particle transport in an equilibrium magnetic field.

PubMed

Yang, Y M; Bednarz, B

2013-02-21

Following the proposal by several groups to integrate magnetic resonance imaging (MRI) with radiation therapy, much attention has been afforded to examining the impact of strong (on the order of a Tesla) transverse magnetic fields on photon dose distributions. The effect of the magnetic field on dose distributions must be considered in order to take full advantage of the benefits of real-time intra-fraction imaging. In this investigation, we compared the handling of particle transport in magnetic fields between two Monte Carlo codes, EGSnrc and Geant4, to analyze various aspects of their electromagnetic transport algorithms; both codes are well-benchmarked for medical physics applications in the absence of magnetic fields. A water-air-water slab phantom and a water-lung-water slab phantom were used to highlight dose perturbations near high- and low-density interfaces. We have implemented a method of calculating the Lorentz force in EGSnrc based on theoretical models in literature, and show very good consistency between the two Monte Carlo codes. This investigation further demonstrates the importance of accurate dosimetry for MRI-guided radiation therapy (MRIgRT), and facilitates the integration of a ViewRay MRIgRT system in the University of Wisconsin-Madison's Radiation Oncology Department.

Consistency evaluation between EGSnrc and Geant4 charged particle transport in an equilibrium magnetic field

NASA Astrophysics Data System (ADS)

Yang, Y. M.; Bednarz, B.

2013-02-01

Following the proposal by several groups to integrate magnetic resonance imaging (MRI) with radiation therapy, much attention has been afforded to examining the impact of strong (on the order of a Tesla) transverse magnetic fields on photon dose distributions. The effect of the magnetic field on dose distributions must be considered in order to take full advantage of the benefits of real-time intra-fraction imaging. In this investigation, we compared the handling of particle transport in magnetic fields between two Monte Carlo codes, EGSnrc and Geant4, to analyze various aspects of their electromagnetic transport algorithms; both codes are well-benchmarked for medical physics applications in the absence of magnetic fields. A water-air-water slab phantom and a water-lung-water slab phantom were used to highlight dose perturbations near high- and low-density interfaces. We have implemented a method of calculating the Lorentz force in EGSnrc based on theoretical models in literature, and show very good consistency between the two Monte Carlo codes. This investigation further demonstrates the importance of accurate dosimetry for MRI-guided radiation therapy (MRIgRT), and facilitates the integration of a ViewRay MRIgRT system in the University of Wisconsin-Madison's Radiation Oncology Department.

The inverse problem to the evaluation of magnetic fields

NASA Astrophysics Data System (ADS)

Caspi, S.; Helm, M.; Laslett, L. J.; Brady, V.

1992-12-01

In the design of superconducting magnet elements, such as may be required to guide and focus ions in a particle accelerator, one frequently premises some particular current distribution and then proceeds to compute the consequent magnetic field through use of the laws of Biot and Savart or of Ampere. When working in this manner one of course may need to revise frequently the postulated current distribution before arriving at a resulting magnetic field of acceptable field quality. It therefore is of interest to consider an alternative ('inverse') procedure in which one specifies a desired character for the field required in the region interior to the winding and undertakes them to evaluate the current distribution on the specified winding surface that would provide this desired field. We may note that in undertaking such an inverse procedure we would wish, on practical grounds, to avoid the use of any 'double-layer' distributions of current on the winding surface or interface but would not demand that no fields be generated in the exterior region, so that in this respect the goal would differ in detail from that discussed by other authors, in analogy to the distribution sought in electrostatics by the so-caged Green's equivalent stratum.

Simultaneous hyperthermia-chemotherapy with controlled drug delivery using single-drug nanoparticles.

PubMed

Sato, Itaru; Umemura, Masanari; Mitsudo, Kenji; Fukumura, Hidenobu; Kim, Jeong-Hwan; Hoshino, Yujiro; Nakashima, Hideyuki; Kioi, Mitomu; Nakakaji, Rina; Sato, Motohiko; Fujita, Takayuki; Yokoyama, Utako; Okumura, Satoshi; Oshiro, Hisashi; Eguchi, Haruki; Tohnai, Iwai; Ishikawa, Yoshihiro

2016-04-22

We previously investigated the utility of μ-oxo N,N'- bis(salicylidene)ethylenediamine iron (Fe(Salen)) nanoparticles as a new anti-cancer agent for magnet-guided delivery with anti-cancer activity. Fe(Salen) nanoparticles should rapidly heat up in an alternating magnetic field (AMF), and we hypothesized that these single-drug nanoparticles would be effective for combined hyperthermia-chemotherapy. Conventional hyperthermic particles are usually made of iron oxide, and thus cannot exhibit anti-cancer activity in the absence of an AMF. We found that Fe(Salen) nanoparticles induced apoptosis in cultured cancer cells, and that AMF exposure enhanced the apoptotic effect. Therefore, we evaluated the combined three-fold strategy, i.e., chemotherapy with Fe(Salen) nanoparticles, magnetically guided delivery of the nanoparticles to the tumor, and AMF-induced heating of the nanoparticles to induce local hyperthermia, in a rabbit model of tongue cancer. Intravenous administration of Fe(Salen) nanoparticles per se inhibited tumor growth before the other two modalities were applied. This inhibition was enhanced when a magnet was used to accumulate Fe(Salen) nanoparticles at the tongue. When an AMF was further applied (magnet-guided chemotherapy plus hyperthermia), the tumor masses were dramatically reduced. These results indicate that our strategy of combined hyperthermia-chemotherapy using Fe(Salen) nanoparticles specifically delivered with magnetic guidance represents a powerful new approach for cancer treatment.

Doxorubicin loaded magnetic polymersomes: theranostic nanocarriers for MR imaging and magneto-chemotherapy.

PubMed

Sanson, Charles; Diou, Odile; Thévenot, Julie; Ibarboure, Emmanuel; Soum, Alain; Brûlet, Annie; Miraux, Sylvain; Thiaudière, Eric; Tan, Sisareuth; Brisson, Alain; Dupuis, Vincent; Sandre, Olivier; Lecommandoux, Sébastien

2011-02-22

Hydrophobically modified maghemite (γ-Fe(2)O(3)) nanoparticles were encapsulated within the membrane of poly(trimethylene carbonate)-b-poly(l-glutamic acid) (PTMC-b-PGA) block copolymer vesicles using a nanoprecipitation process. This formation method gives simple access to highly magnetic nanoparticles (MNPs) (loaded up to 70 wt %) together with good control over the vesicles size (100-400 nm). The simultaneous loading of maghemite nanoparticles and doxorubicin was also achieved by nanoprecipitation. The deformation of the vesicle membrane under an applied magnetic field has been evidenced by small angle neutron scattering. These superparamagnetic hybrid self-assemblies display enhanced contrast properties that open potential applications for magnetic resonance imaging. They can also be guided in a magnetic field gradient. The feasibility of controlled drug release by radio frequency magnetic hyperthermia was demonstrated in the case of encapsulated doxorubicin molecules, showing the viability of the concept of magneto-chemotherapy. These magnetic polymersomes can be used as efficient multifunctional nanocarriers for combined therapy and imaging.

Fluctuation dynamics in reconnecting current sheets

NASA Astrophysics Data System (ADS)

von Stechow, Adrian; Grulke, Olaf; Ji, Hantao; Yamada, Masaaki; Klinger, Thomas

2015-11-01

During magnetic reconnection, a highly localized current sheet forms at the boundary between opposed magnetic fields. Its steep perpendicular gradients and fast parallel drifts can give rise to a range of instabilities which can contribute to the overall reconnection dynamics. In two complementary laboratory reconnection experiments, MRX (PPPL, Princeton) and VINETA.II (IPP, Greifswald, Germany), magnetic fluctuations are observed within the current sheet. Despite the large differences in geometries (toroidal vs. linear), plasma parameters (high vs. low beta) and magnetic configuration (low vs. high magnetic guide field), similar broadband fluctuation characteristics are observed in both experiments. These are identified as Whistler-like fluctuations in the lower hybrid frequency range that propagate along the current sheet in the electron drift direction. They are intrinsic to the localized current sheet and largely independent of the slower reconnection dynamics. This contribution characterizes these magnetic fluctuations within the wide parameter range accessible by both experiments. Specifically, the fluctuation spectra and wave dispersion are characterized with respect to the magnetic topology and plasma parameters of the reconnecting current sheet.

Reconstruction of the static magnetic field of a magnetron

NASA Astrophysics Data System (ADS)

Krüger, Dennis; Köhn, Kevin; Gallian, Sara; Brinkmann, Ralf Peter

2018-06-01

The simulation of magnetron discharges requires a quantitatively correct mathematical model of the magnetic field structure. This study presents a method to construct such a model on the basis of a spatially restricted set of experimental data and a plausible a priori assumption on the magnetic field configuration. The example in focus is that of a planar circular magnetron. The experimental data are Hall probe measurements of the magnetic flux density in an accessible region above the magnetron plane [P. D. Machura et al., Plasma Sources Sci. Technol. 23, 065043 (2014)]. The a priori assumption reflects the actual design of the device, and it takes the magnetic field emerging from a center magnet of strength m C and vertical position d C and a ring magnet of strength m R , vertical position d R , and radius R. An analytical representation of the assumed field configuration can be formulated in terms of generalized hypergeometric functions. Fitting the ansatz to the experimental data with a least square method results in a fully specified analytical field model that agrees well with the data inside the accessible region and, moreover, is physically plausible in the regions outside of it. The outcome proves superior to the result of an alternative approach which starts from a multimode solution of the vacuum field problem formulated in terms of polar Bessel functions and vertical exponentials. As a first application of the obtained field model, typical electron and ion Larmor radii and the gradient and curvature drift velocities of the electron guiding center are calculated.

MR-guided breast radiotherapy: feasibility and magnetic-field impact on skin dose

NASA Astrophysics Data System (ADS)

van Heijst, Tristan C. F.; den Hartogh, Mariska D.; Lagendijk, Jan J. W.; Desirée van den Bongard, H. J. G.; van Asselen, Bram

2013-09-01

The UMC Utrecht MRI/linac (MRL) design provides image guidance with high soft-tissue contrast, directly during radiotherapy (RT). Breast cancer patients are a potential group to benefit from better guidance in the MRL. However, due to the electron return effect, the skin dose can be increased in presence of a magnetic field. Since large skin areas are generally involved in breast RT, the purpose of this study is to investigate the effects on the skin dose, for whole-breast irradiation (WBI) and accelerated partial-breast irradiation (APBI). In ten patients with early-stage breast cancer, targets and organs at risk (OARs) were delineated on postoperative CT scans co-registered with MRI. The OARs included the skin, comprising the first 5 mm of ipsilateral-breast tissue, plus extensions. Three intensity-modulated RT techniques were considered (2× WBI, 1× APBI). Individual beam geometries were used for all patients. Specially developed MRL treatment-planning software was used. Acceptable plans were generated for 0 T, 0.35 T and 1.5 T, using a class solution. The skin dose was augmented in WBI in the presence of a magnetic field, which is a potential drawback, whereas in APBI the induced effects were negligible. This opens possibilities for developing MR-guided partial-breast treatments in the MRL.

On the Induced Flow of an Electrically Conducting Liquid in a Rectangular Duct by Electric and Magnetic Fields of Finite Extent

NASA Technical Reports Server (NTRS)

Rossow, Vernon J.; Jones, William Prichard; Huerta, Robert H.

1961-01-01

Reported here are the results of a systematic study of a model of the direct-current electromagnetic pump. Of particular interest is the motion imparted to the electrically conducting fluid in the rectangular duct by the body forces that result from applied electric and magnetic fields. The purpose of the investigation is to associate the observed fluid motion with the characteristics of the electric and magnetic fields which cause them. The experiments were carried out with electromagnetic fields that moved a stream of copper sulphate solution through a clear plastic channel. Ink filaments injected into the stream ahead of the region where the fields were applied identify the motion of the fluid elements as they passed through the test channel. Several magnetic field configurations were employed with a two-dimensional electric current distribution in order to study and identify the magnitude of some of the effects on the fluid motion brought about by nonuniformities in the electromagnetic fields. A theoretical analysis was used to guide and evaluate the identification of the several fluid motions observed. The agreement of the experimental data with the theoretical predictions is satisfactory. It is found that sizable variations in the velocity profile and pressure head of the output stream are produced by the shape of the electric and magnetic fields.

Using ferromagnetic nanoparticles with low Curie temperature for magnetic resonance imaging-guided thermoablation

PubMed Central

Herynek, Vít; Turnovcová, Karolína; Veverka, Pavel; Dědourková, Tereza; Žvátora, Pavel; Jendelová, Pavla; Gálisová, Andrea; Kosinová, Lucie; Jiráková, Klára; Syková, Eva

2016-01-01

Introduction Magnetic nanoparticles (NPs) represent a tool for use in magnetic resonance imaging (MRI)-guided thermoablation of tumors using an external high-frequency (HF) magnetic field. To avoid local overheating, perovskite NPs with a lower Curie temperature (Tc) were proposed for use in thermotherapy. However, deposited power decreases when approaching the Curie temperature and consequently may not be sufficient for effective ablation. The goal of the study was to test this hypothesis. Methods Perovskite NPs (Tc =66°C–74°C) were characterized and tested both in vitro and in vivo. In vitro, the cells suspended with NPs were exposed to a HF magnetic field together with control samples. In vivo, a NP suspension was injected into a induced tumor in rats. Distribution was checked by MRI and the rats were exposed to a HF field together with control animals. Apoptosis in the tissue was evaluated. Results and discussion In vitro, the high concentration of suspended NPs caused an increase of the temperature in the cell sample, leading to cell death. In vivo, MRI confirmed distribution of the NPs in the tumor. The temperature in the tumor with injected NPs did not increase substantially in comparison with animals without particles during HF exposure. We proved that the deposited power from the NPs is too small and that thermoregulation of the animal is sufficient to conduct the heat away. Histology did not detect substantially higher apoptosis in NP-treated animals after ablation. Conclusion Magnetic particles with low Tc can be tracked in vivo by MRI and heated by a HF field. The particles are capable of inducing cell apoptosis in suspensions in vitro at high concentrations only. However, their effect in the case of extracellular deposition in vivo is questionable due to low deposited power and active thermoregulation of the tissue. PMID:27540292

Magnetic Nanoliposomes as in Situ Microbubble Bombers for Multimodality Image-Guided Cancer Theranostics.

PubMed

Liu, Yang; Yang, Fang; Yuan, Chuxiao; Li, Mingxi; Wang, Tuantuan; Chen, Bo; Jin, Juan; Zhao, Peng; Tong, Jiayi; Luo, Shouhua; Gu, Ning

2017-02-28

Nanosized drug delivery systems have offered promising approaches for cancer theranostics. However, few are effective to simultaneously maximize tumor-specific uptake, imaging, and therapy in a single nanoplatform. Here, we report a simple yet stimuli-responsive anethole dithiolethione (ADT)-loaded magnetic nanoliposome (AML) delivery system, which consists of ADT, hydrogen sulfide (H 2 S) pro-drug, doped in the lipid bilayer, and superparamagnetic nanoparticles encapsulated inside. HepG2 cells could be effectively bombed after 6 h co-incubation with AMLs. For in vivo applications, after preferentially targeting the tumor tissue when spatiotemporally navigated by an external magnetic field, the nanoscaled AMLs can intratumorally convert to microsized H 2 S bubbles. This dynamic process can be monitored by magnetic resonance and ultrasound dual modal imaging. Importantly, the intratumoral generated H 2 S bubbles imaged by real-time ultrasound imaging first can bomb to ablate the tumor tissue when exposed to higher acoustic intensity; then as gasotransmitters, intratumoral generated high-concentration H 2 S molecules can diffuse into the inner tumor regions to further have a synergetic antitumor effect. After 7-day follow-up observation, AMLs with magnetic field treatments have indicated extremely significantly higher inhibitions of tumor growth. Therefore, such elaborately designed intratumoral conversion of nanostructures to microstructures has exhibited an improved anticancer efficacy, which may be promising for multimodal image-guided accurate cancer therapy.

Air-electron stream interactions during magnetic resonance IGRT : Skin irradiation outside the treatment field during accelerated partial breast irradiation.

PubMed

Park, Jong Min; Shin, Kyung Hwan; Kim, Jung-In; Park, So-Yeon; Jeon, Seung Hyuck; Choi, Noorie; Kim, Jin Ho; Wu, Hong-Gyun

2018-01-01

To investigate and to prevent irradiation outside the treatment field caused by an electron stream in the air generated by the magnetic field during magnetic resonance image-guided accelerated partial breast irradiation (APBI). In all, 20 patients who received APBI with a magnetic resonance image-guided radiation therapy (MR-IGRT) system were prospectively studied. The prescription dose was 38.5 Gy in 10 fractions of 3.85 Gy and delivered with a tri-cobalt system (the ViewRay system). For each patient, primary plans were delivered for the first five fractions and modified plans with different gantry angles from those of the primary plan (in-treatment plans) were delivered for the remaining five fractions to reduce the skin dose. A 1 cm thick bolus was placed in front of the patient's jaw, ipsilateral shoulder, and arm to shield them from the electron stream. Radiochromic EBT3 films were attached to the front (towards the breast) and back (towards the head) of the bolus during treatment. Correlations between the measured values and the tumor locations, treatment times, and tumor sizes were investigated. For a single fraction delivery, the average areas of the measured isodoses of 14% (0.54 Gy), 12% (0.46 Gy), and 10% (0.39 Gy) at the front of the boluses were as large as 3, 10.4, and 21.4 cm 2 , respectively, whereas no significant dose could be measured at the back of the boluses. Statistically significant but weak correlations were observed between the measured values and the treatment times. During radiotherapy for breast cancer with an MR-IGRT system, the patient must be shielded from electron streams in the air generated by the interaction of the magnetic field with the beams of the three-cobalt treatment unit to avoid unwanted irradiation of the skin outside the treatment field.

A magnetic-bottle multi-electron-ion coincidence spectrometer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matsuda, Akitaka; Hishikawa, Akiyoshi; Department of Chemistry, Nagoya University, Furo-cho, Chikusa, Nagoya, Aichi 464-8602

2011-10-15

A novel multi-electron-ion coincidence spectrometer developed on the basis of a 1.5 m-long magnetic-bottle electron spectrometer is presented. Electrons are guided by an inhomogeneous magnetic field to a detector at the end of the flight tube, while a set of optics is used to extract counterpart ions to the same detector, by a pulsed inhomogeneous electric field. This setup allows ion detection with high mass resolution, without impairing the high collection efficiency for electrons. The performance of the coincidence spectrometer was tested with double ionization of carbon disulfide, CS{sub 2} {yields} CS{sub 2}{sup 2+} + e{sup -} + e{sup -},more » in ultrashort intense laser fields (2.8 x 10{sup 13} W/cm{sup 2}, 280 fs, 1030 nm) to clarify the electron correlation below the rescattering threshold.« less

Higher order Larmor radius corrections to guiding-centre equations and application to fast ion equilibrium distributions

NASA Astrophysics Data System (ADS)

Lanthaler, S.; Pfefferlé, D.; Graves, J. P.; Cooper, W. A.

2017-04-01

An improved set of guiding-centre equations, expanded to one order higher in Larmor radius than usually written for guiding-centre codes, are derived for curvilinear flux coordinates and implemented into the orbit following code VENUS-LEVIS. Aside from greatly improving the correspondence between guiding-centre and full particle trajectories, the most important effect of the additional Larmor radius corrections is to modify the definition of the guiding-centre’s parallel velocity via the so-called Baños drift. The correct treatment of the guiding-centre push-forward with the Baños term leads to an anisotropic shift in the phase-space distribution of guiding-centres, consistent with the well-known magnetization term. The consequence of these higher order terms are quantified in three cases where energetic ions are usually followed with standard guiding-centre equations: (1) neutral beam injection in a MAST-like low aspect-ratio spherical equilibrium where the fast ion driven current is significantly larger with respect to previous calculations, (2) fast ion losses due to resonant magnetic perturbations where a lower lost fraction and a better confinement is confirmed, (3) alpha particles in the ripple field of the European DEMO where the effect is found to be marginal.

Size-dependent avoidance of a strong magnetic anomaly in Caribbean spiny lobsters.

PubMed

Ernst, David A; Lohmann, Kenneth J

2018-03-01

On a global scale, the geomagnetic field varies predictably across the Earth's surface, providing animals that migrate long distances with a reliable source of directional and positional information that can be used to guide their movements. In some locations, however, magnetic minerals in the Earth's crust generate an additional field that enhances or diminishes the overall field, resulting in unusually steep gradients of field intensity within a limited area. How animals respond to such magnetic anomalies is unclear. The Caribbean spiny lobster, Panulirus argus , is a benthic marine invertebrate that possesses a magnetic sense and is likely to encounter magnetic anomalies during migratory movements and homing. As a first step toward investigating whether such anomalies affect the behavior of lobsters, a two-choice preference experiment was conducted in which lobsters were allowed to select one of two artificial dens, one beneath a neodymium magnet and the other beneath a non-magnetic weight of similar size and mass (control). Significantly more lobsters selected the control den, demonstrating avoidance of the magnetic anomaly. In addition, lobster size was found to be a significant predictor of den choice: lobsters that selected the anomaly den were significantly smaller as a group than those that chose the control den. Taken together, these findings provide additional evidence for magnetoreception in spiny lobsters, raise the possibility of an ontogenetic shift in how lobsters respond to magnetic fields, and suggest that magnetic anomalies might influence lobster movement in the natural environment. © 2018. Published by The Company of Biologists Ltd.

On matching the anode ring with the magnetic field in an ATON-type Hall effect thruster

NASA Astrophysics Data System (ADS)

Liu, Jinwen; Li, Hong; Zhang, Xu; Ding, Yongjie; Wei, Liqiu; Li, Jianzhi; Yu, Daren; Wang, Xiaogang

2018-06-01

In an ATON-type Hall effect thruster, a ring-shaped anode and a cusped magnetic field intersect the match between the anode shape and the field topology thus must be clarified to optimize the electron transport to the anode and consequently the design of a high-efficiency thruster. By changing the match pattern with both the change in the length of the anode ring and the axial displacement of the cusp magnetic field, this study experimentally investigated the influence of the match pattern on the discharge characteristics of an ATON-type thruster—P100—under the condition of a moderate discharge voltage. The experimental results show that there is a match pattern that always optimizes the performance of the P100 thruster. At the rated operation parameters (300 V of discharge voltage and 5 mg/s of propellant mass flow rate) and the rated magnetic field strength, the observed improvements on thrust (˜79 mN to ˜85 mN) and anode efficiency (˜46% to ˜55%) are significant. Through further theoretical analysis, this study revealed that the change in the characteristics of electron momentum and energy transfer in the near-anode region, induced by the change of the match pattern, is the basic reason. The findings of this work are instructive for both understanding the electron motion in a cusp magnetic field and guiding the design of the anode ring intersecting with a cusp magnetic field in an ATON-type Hall effect thruster.

Effect of transverse magnetic fields on a simulated in-line 6 MV linac

NASA Astrophysics Data System (ADS)

St. Aubin, J.; Steciw, S.; Fallone, B. G.

2010-08-01

The effects of a transverse magnetic field on an in-line side-coupled 6 MV linear accelerator are given. The results are directly applicable to a linac-MR system used for real-time image guided adaptive radiotherapy. Our previously designed end-to-end linac simulation incorporated the results from the axisymmetric 2D electron gun program EGN2w. However, since the magnetic fields being investigated are non-axisymmetric in nature for the work presented here, the electron gun simulation was performed using OPERA-3d/SCALA. The simulation results from OPERA-3d/SCALA showed excellent agreement with previous results. Upon the addition of external magnetic fields to our fully 3D linac simulation, it was found that a transverse magnetic field of 6 G resulted in a 45 ± 1% beam loss, and by 14 G, no electrons were incident on the target. Transverse magnetic fields on the linac simulation produced a highly asymmetric focal spot at the target, which translated into a 13% profile asymmetry at 6 G. Upon translating the focal spot with respect to the target coordinates, profile symmetry was regained at the expense of a lateral shift in the dose profiles. It was found that all points in the penumbra failed a 1%/1 mm acceptance criterion for fields between 4 and 6 G. However, it was also found that the lateral profile shifts were corrected by adjusting the jaw positions asymmetrically.

Troubleshooting Micro's.

ERIC Educational Resources Information Center

Black, B. R.

This guide provides instructions for preventive maintenance and for making minor technical adjustments on microcomputers. General hints are provided for all microcomputers concerning static electricity reduction; use of dust covers; heat, magnetic fields, and floppy disks; and the use of halogen fire extinguishers. These are followed by…

Angular dependence of the magnetic properties of permalloy and nickel nanowires as a function of their diameters

NASA Astrophysics Data System (ADS)

Raviolo, Sofía; Tejo, Felipe; Bajales, Noelia; Escrig, Juan

2018-01-01

In this paper we have compared the angular dependence of the magnetic properties of permalloy (Ni80Fe20) and nickel nanowires by means of micromagnetic simulations. For each material we have chosen two diameters, 40 and 100 nm. Permalloy nanowires with smaller diameters (d = 40 nm) exhibit greater coercivity than nickel nanowires, regardless of the angle at which the external magnetic field is applied. In addition, both Py and Ni nanowires exhibit the same remanence values. However, the nanowires of larger diameters (d = 100 nm) exhibit a more complex behavior, noting that for small angles, nickel nanowires are those that now exhibit a greater coercivity in comparison to those of permalloy. The magnetization reversal modes vary as a function of the angle at which the external field is applied. When the field is applied parallel to the wire axis, it reverts through nucleation and propagation of domain walls, whereas when the field is applied perpendicular to the axis, it reverts by a pseudo-coherent rotation. These results may provide a guide to control the magnetic properties of nanowires for use in potential applications.

The Relation between Reconnected Flux, the Parallel Electric Field, and the Reconnection Rate in a Three-Dimensional Kinetic Simulation of Magnetic Reconnection

NASA Astrophysics Data System (ADS)

Wendel, D. E.; Olson, D. K.; Hesse, M.; Karimabadi, H.; Daughton, W. S.

2013-12-01

We investigate the distribution of parallel electric fields and their relationship to the location and rate of magnetic reconnection of a large particle-in-cell simulation of 3D turbulent magnetic reconnection with open boundary conditions. The simulation's guide field geometry inhibits the formation of topological features such as separators and null points. Therefore, we derive the location of potential changes in magnetic connectivity by finding the field lines that experience a large relative change between their endpoints, i.e., the quasi-separatrix layer. We find a correspondence between the locus of changes in magnetic connectivity, or the quasi-separatrix layer, and the map of large gradients in the integrated parallel electric field (or quasi-potential). Furthermore, we compare the distribution of parallel electric fields along field lines with the reconnection rate. We find the reconnection rate is controlled by only the low-amplitude, zeroth and first-order trends in the parallel electric field, while the contribution from high amplitude parallel fluctuations, such as electron holes, is negligible. The results impact the determination of reconnection sites within models of 3D turbulent reconnection as well as the inference of reconnection rates from in situ spacecraft measurements. It is difficult through direct observation to isolate the locus of the reconnection parallel electric field amidst the large amplitude fluctuations. However, we demonstrate that a positive slope of the partial sum of the parallel electric field along the field line as a function of field line length indicates where reconnection is occurring along the field line.

Gyrofluid modeling and phenomenology of low-βe Alfvén wave turbulence

NASA Astrophysics Data System (ADS)

Passot, T.; Sulem, P. L.; Tassi, E.

2018-04-01

A two-field reduced gyrofluid model including electron inertia, ion finite Larmor radius corrections, and parallel magnetic field fluctuations is derived from the model of Brizard [Brizard, Phys. Fluids B 4, 1213 (1992)]. It assumes low βe, where βe indicates the ratio between the equilibrium electron pressure and the magnetic pressure exerted by a strong uniform magnetic guide field, but permits an arbitrary ion-to-electron equilibrium temperature ratio. It is shown to have a noncanonical Hamiltonian structure and provides a convenient framework for studying kinetic Alfvén wave turbulence, from magnetohydrodynamics to sub-de scales (where de holds for the electron skin depth). Magnetic energy spectra are phenomenologically determined within energy and generalized cross-helicity cascades in the perpendicular spectral plane. Arguments based on absolute statistical equilibria are used to predict the direction of the transfers, pointing out that, within the sub-ion range, the generalized cross-helicity could display an inverse cascade if injected at small scales, for example by reconnection processes.

Folded waveguide coupler

DOEpatents

Owens, Thomas L.

1988-03-01

A resonant cavity waveguide coupler for ICRH of a magnetically confined plasma. The coupler consists of a series of inter-leaved metallic vanes disposed withn an enclosure analogous to a very wide, simple rectangular waveguide that has been "folded" several times. At the mouth of the coupler, a polarizing plate is provided which has coupling apertures aligned with selected folds of the waveguide through which rf waves are launched with magnetic fields of the waves aligned in parallel with the magnetic fields confining the plasma being heated to provide coupling to the fast magnetosonic wave within the plasma in the frequency usage of from about 50-200 mHz. A shorting plate terminates the back of the cavity at a distance approximately equal to one-half the guide wavelength from the mouth of the coupler to ensure that the electric field of the waves launched through the polarizing plate apertures are small while the magnetic field is near a maximum. Power is fed into the coupler folded cavity by means of an input coaxial line feed arrangement at a point which provides an impedance match between the cavity and the coaxial input line.

TU-H-BRA-05: A System Design for Integration of An Interior MRI and a Linear Accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mao, W; Henry Ford Hospital, Detroit, MI; Wang, G

Purpose: MRI is a highly desirable modality to guide radiation therapy but it is difficult to combine a conventional MRI scanner directly with a linear accelerator (linac). An interior MRI (iMRI) concept has been proposed to acquire MRI images within a small field of view only covering targets and immediate surrounding tissues. The objective of this project is to design an interior MRI system to work with a linac using a magnet to provide a field around 0.2T in a cube of 20cm per side, and perform image reconstruction with a slightly inhomogeneous static magnetic fields. Methods: All the resultsmore » are simulated using a commercially available software package, FARADY. In our design, a ring structure holds the iMRI system and also imbeds a linac treatment head. The ring is synchronized to the linac gantry rotation. Half of the ring is made of steel and becomes a magnetic flux return path (yoke) so that a strong magnetic field will be limited inside the iron circuit and fringe fields will be very weak. In order to increase the static magnetic field homogeneity, special steel magnet boots or tips were simulated. Three curved boots were designed based on two-dimensional curves: arc, parabola and hyperbola. Results: Different boot surfaces modify magnetic field distributions differently. With the same pair of neodymium-iron-boron (NdFeB) magnets, the magnetic induction at the centers are 0.217T, 0.201T, 0.204T, and 0.212T for flat, arc, parabola and hyperbola boots, respectively. The hyperbola boots lead to the most homogeneous results, the static magnetic field deviations are within 0.5% in a cube of 20cm, and can be further improved using shimming techniques. Conclusion: This study supports the concept of an iMRI design. Successful development of iMRI will provide crucial information for tumor delineation in radiation therapy.« less

Partition of Heating During Magnetic Reconnection: Role of Exhaust Velocity

NASA Astrophysics Data System (ADS)

Haggerty, C. C.; Shay, M.; Drake, J. F.; Phan, T.; Chasapis, A.; Cassak, P.; Malakit, K.

2017-12-01

The partition of released magnetic energy into ion and electron bulk flow and thermal energy is an important problem that has recently become under intense scrutiny in the magnetosphere and heliosphere. In the strong magnetic shear limit of magnetic reconnection (low guide field), the production of counter-streaming beams due to magnetic field line contraction plays an important role in heating the plasma. The contraction velocity or outflow velocity controls the magnitude of the heating. Although it is known that often the outflow velocity is less than the upstream Alfvén speed, an understanding of why this is so is lacking. We show that the outflow velocity in reconnection is reduced by the parallel ion exhaust temperature and derive a scaling relationship for this effect. This prediction is found to be consistent with both kinetic PIC simulations and MMS satellite observations. This scaling for the outflow is then applied to a general theory for plasma heating during magnetic reconnection.

Mapping Ion and Electron Remagnetization Distance in the Reconnection Outflow Exhaust Region with MMS

NASA Astrophysics Data System (ADS)

Sturner, A. P.; Eriksson, S.; Gershman, D. J.; Plaschke, F.; Burch, J.

2017-12-01

Magnetopause current sheets have been fertile ground for understanding kinetic-scale physics of magnetic reconnection, but can also be used to study more macroscopic scale phenomena statistically. Post-reconnection, magnetic flux and plasma are accelerated away from the x-line into exhaust regions. As the exhausting plasma exits the electron diffusion region, electrons become remagnetized and are accelerated by the magnetic field into an E x B jet while the ions remain unmagnetized. Further along the exhaust, at the edge of the ion diffusion region, the ions become frozen into the magnetic field, and are accelerated to join the electrons in the exhaust jet. By assuming a constant reconnection rate of 0.1, we can infer the distance to the x-line from the normal width of the exhaust. We present a statistical study using the Magnetospheric Multiscale Mission (MMS) to map out the electron and ion remagnetization distances that define the edge of the electron and ion diffusion regions for magnetopause reconnection, and explore the effects of a guide magnetic field.

Development of a Pneumatic Robot for MRI-guided Transperineal Prostate Biopsy and Brachytherapy: New Approaches

PubMed Central

Song, Sang-Eun; Cho, Nathan B.; Fischer, Gregory; Hata, Nobuhito; Tempany, Clare; Fichtinger, Gabor; Iordachita, Iulian

2011-01-01

Magnetic Resonance Imaging (MRI) guided prostate biopsy and brachytherapy has been introduced in order to enhance the cancer detection and treatment. For the accurate needle positioning, a number of robotic assistants have been developed. However, problems exist due to the strong magnetic field and limited workspace. Pneumatically actuated robots have shown the minimum distraction in the environment but the confined workspace limits optimal robot design and thus controllability is often poor. To overcome the problem, a simple external damping mechanism using timing belts was sought and a 1-DOF mechanism test result indicated sufficient positioning accuracy. Based on the damping mechanism and modular system design approach, a new workspace-optimized 4-DOF parallel robot was developed for the MRI-guided prostate biopsy and brachytherapy. A preliminary evaluation of the robot was conducted using previously developed pneumatic controller and satisfying results were obtained. PMID:21399734

The current status and future direction of high magnetic field science in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lancaster, James

2013-11-01

This grant provided partial support for the National Research Council (NRC) study that assesses the current status of high magnetic field research in the United States and provides recommendations to guide the future of research and technology development for this area given the needs of user communities and in the context of other programs worldwide. A pdf version of the report is available for download, for free, at http://www.nap.edu/catalog.php?record_id=18355. The science drivers fall into 4 broad areas—(1) condensed matter and materials physics; (2) chemistry, biochemistry, and biology; (3) medical and life science studies; and (4) other fields such as high-energymore » physics, plasma physics, and particle astrophysics. Among the topics covered in the report’s findings, conclusions, and recommendations are a recognition that there is a continuing need for a centralized facility but also that clear benefits will flow to research communities from decentralized facilities. According to the report, support agencies should evaluate whether to establish such facilities when 32 Tesla superconducting magnets become available. The report also recommends the provision of facilities that combine magnetic fields with scattering facilities and THz radiation sources, and sets out specific magnet goals for magnets needed in several areas of research.« less

Modeling of Magnetoelastic Nanostructures with a Fully-coupled Mechanical-Micromagnetic Model and Its Applications

NASA Astrophysics Data System (ADS)

Liang, Cheng-Yen

Micromagnetic simulations of magnetoelastic nanostructures traditionally rely on either the Stoner-Wohlfarth model or the Landau-Lifshitz-Gilbert (LLG) model assuming uniform strain (and/or assuming uniform magnetization). While the uniform strain assumption is reasonable when modeling magnetoelastic thin films, this constant strain approach becomes increasingly inaccurate for smaller in-plane nanoscale structures. In this dissertation, a fully-coupled finite element micromagnetic method is developed. The method deals with the micromagnetics, elastodynamics, and piezoelectric effects. The dynamics of magnetization, non-uniform strain distribution, and electric fields are iteratively solved. This more sophisticated modeling technique is critical for guiding the design process of the nanoscale strain-mediated multiferroic elements such as those needed in multiferroic systems. In this dissertation, we will study magnetic property changes (e.g., hysteresis, coercive field, and spin states) due to strain effects in nanostructures. in addition, a multiferroic memory device is studied. The electric-field-driven magnetization switching by applying voltage on patterned electrodes simulation in a nickel memory device is shown in this work. The deterministic control law for the magnetization switching in a nanoring with electric field applied to the patterned electrodes is investigated. Using the patterned electrodes, we show that strain-induced anisotropy is able to be controlled, which changes the magnetization deterministically in a nano-ring.

Toys in Space, 2

NASA Technical Reports Server (NTRS)

Herbert, Dexter (Editor)

1993-01-01

In this educational video from the 'Liftoff to Learning' series, astronauts from the STS-54 Mission (Mario Runco, John Casper, Don McMonagle, Susan Helms, and Greg Harbaugh) explain how microgravity and weightlessness in space affects motion by using both mechanical and nonmechanical toys (gravitrons, slinkys, dart boards, magnetic marbles, and others). The gravitational effects on rotation, force, acceleration, magnetism, magnetic fields, center of axis, and velocity are actively demonstrated using these toys through experiments onboard the STS-54 Mission flight as a part of their spaceborne experiment payload. [Resource Guide referenced in the video is not available.

Guidance of Magnetic Nanocontainers for Treating Alzheimer's Disease Using an Electromagnetic, Targeted Drug-Delivery Actuator.

PubMed

Do, Ton Duc; Ul Amin, Faiz; Noh, Yeongil; Kim, Myeong Ok; Yoon, Jungwon

2016-03-01

The "impermeability" of the blood-brain barrier (BBB) has hindered effective treatment of central nervous system (CNS) disorders such as Alzheimer's disease (AD), which is one of the most common neurodegenerative disorders. A drug can be delivered to a targeted disease site effectively by applying a strong electromagnetic force to the conjugate of a drug and magnetic nanocontainers. This study developed a novel nanotechnology-based strategy to deliver therapeutic agents to the brain via the BBB as a possible therapeutic approach for AD. First, a novel approach for an electromagnetic actuator for guiding nanocontainers is introduced. Then, we analyzed the in vivo uptake in mice experimentally to evaluate the capacity of the nanocontainers. In the mouse model, we demonstrated that magnetic particles can cross the normal BBB when subjected to external electromagnetic fields of 28 mT (0.43 T/m) and 79.8 mT (1.39 T/m). Our study also assessed the differential effects of pulsed (0.25, 0.5, and 1 Hz) and constant magnetic fields on the transport of particles across the BBB in mice injected with magnetic nanoparticles (MNPs) via a tail vein. The applied magnetic field was either kept constant or pulsed on and off. Relative to a constant magnetic field, the rate of MNP uptake and transport across the BBB was enhanced significantly by a pulsed magnetic field. Localization inside the brain was established using fluorescent MNPs. These results using 770-nm fluorescent carboxyl magnetic nanocontainers demonstrated the feasibility of the proposed electromagnetic targeted drug delivery actuator. These results establish an effective strategy for regulating the biodistribution of MNPs in the brain through the application of an external electromagnetic field. This might be a valuable targeting system for AD diagnosis and therapy.

General relativistic razor-thin disks with magnetically polarized matter

NASA Astrophysics Data System (ADS)

Navarro-Noguera, Anamaría; Lora-Clavijo, F. D.; González, Guillermo A.

2018-06-01

The origin of magnetic fields in the universe still remains unknown and constitutes one of the most intriguing questions in astronomy and astrophysics. Their significance is enormous since they have a strong influence on many astrophysical phenomena. In regards of this motivation, theoretical models of galactic disks with sources of magnetic field may contribute to understand the physics behind them. Inspired by this, we present a new family of analytical models for thin disks composed by magnetized material. The solutions are axially symmetric, conformastatic and are obtained by solving the Einstein-Maxwell Field Equations for continuum media without the test field approximation, and assuming that the sources are razor-thin disk of magnetically polarized matter. We find analytical expressions for the surface energy density, the pressure, the polarization vector, the electromagnetic fields, the mass and the rotational velocity for circular orbits, for two particular solutions. In each case, the energy-momentum tensor agrees with the energy conditions and also the convergence of the mass for all the solutions is proved. Since the solutions are well-behaved, they may be used to model astrophysical thin disks, and also may contribute as initial data in numerical simulations. In addition, the process to obtain the solutions is described in detail, which may be used as a guide to find solutions with magnetized material in General Relativity.

Modeling of Field-Aligned Guided Echoes in the Plasmasphere

NASA Technical Reports Server (NTRS)

Fung, Shing F.; Green, James L.

2004-01-01

The conditions under which high frequency (f>>f(sub uh)) long-range extraordinary-mode discrete field-aligned echoes observed by the Radio Plasma Imager (RPI) on board the Imager for Magnetopause-to-Aurora Global Exploration (IMAGE) satellite in the plasmasphere are investigated by ray tracing modeling. Field-aligned discrete echoes are most commonly observed by RPI in the plasmasphere although they are also observed over the polar cap region. The plasmasphere field-aligned echoes appearing as multiple echo traces at different virtual ranges are attributed to signals reflected successively between conjugate hemispheres that propagate along or nearly along closed geomagnetic field lines. The ray tracing simulations show that field-aligned ducts with as little as 1% density perturbations (depletions) and less than 10 wavelengths wide can guide nearly field-aligned propagating high frequency X mode waves. Effective guidance of wave at a given frequency and wave normal angle (Psi) depends on the cross-field density scale of the duct, such that ducts with stronger density depletions need to be wider in order to maintain the same gradient of refractive index across the magnetic field. While signal guidance by field aligned density gradient without ducting is possible only over the polar region, conjugate field-aligned echoes that have traversed through the equatorial region are most likely guided by ducting.

A Longitudinal Mode Electromagnetic Acoustic Transducer (EMAT) Based on a Permanent Magnet Chain for Pipe Inspection.

PubMed

Cong, Ming; Wu, Xinjun; Qian, Chunqiao

2016-05-21

A new electromagnetic acoustic transducer (EMAT) design, employing a special structure of the permanent magnet chain, is proposed to generate and receive longitudinal guided waves for pipe inspection based on the magnetostriction mechanism. Firstly, a quantitative analysis of the excitation forces shows the influence of the radial component can be ignored. Furthermore, as the axial component of the static magnetic field is dominant, a method of solenoid testing coils connected in series is adopted to increase the signal amplitude. Then, two EMAT configurations are developed to generate and receive the L(0,2) guided wave mode. The experimental results show the circumferential notch can be identified and located successfully. Finally, a detailed investigation of the performance of the proposed EMATs is given. Compared to the conventional EMAT configuration, the proposed configurations have the advantages of small volume, light weight, easy installation and portability, which is helpful to improve inspection efficiency.

Double Magnetic Reconnection Driven by Kelvin-Helmholtz Vortices

NASA Astrophysics Data System (ADS)

Horton, W., Jr.; Faganello, M.; Califano, F.; Pegoraro, F.

2017-12-01

Simulations and theory for the solar wind driven magnetic reconnection in the flanks of the magnetopause is shown to be intrinsically 3D with the secular growth of couple pairs of reconnection regions off the equatorial plane. We call the process double mid-latitude reconnection and show supporting 3D simulations and theory descripting the secular growth of the magnetic reconnection with the resulting mixing of the solar wind plasma with the magnetosphere plasma. The initial phase develops Kelvin-Helmholtz vortices at low-latitude and, through the propagation of Alfven waves far from the region where the stresses are generated, creates a standard quasi-2D low latitude boundary layer magnetic reconnection but off the equatorial plane and with a weak guide field component. The reconnection exponential growth is followed by a secularly growing nonlinear phase that gradually closes the solar wind field lines on the Earth. The nonlinear field line structure provides a channel for penetration of the SW plasma into the MS as observed by spacecraft [THEMIS and Cluster]. The simulations show the amount of solar wind plasma brought into the magnetosphere by tracing the time evolution of the areas corresponding to double reconnected field lines with Poincare maps. The results for the solar wind plasma brought into the magnetosphere seems consistent with the observed plasma transport. Finally, we have shown how the intrinsic 3D nature of the doubly reconnected magnetic field lines leads to the generation of twisted magnetic spatial structures that differ from the quasi-2D magnetic islands structures.

Measurement of Magnetic Field Uniformity For a Neutron Electric Dipole Moment Detector with New Lead Endcaps

NASA Astrophysics Data System (ADS)

Kulkarni, Anita; Filippone, Bradley; Slutsky, Simon; Swank, Christopher; Carr, Robert; Osthelder, Charles; Biswas, Aritra; Molina, Daniel

2016-09-01

Over the last several decades, physicists have been measuring the neutron electric dipole moment (nEDM) with greater and greater sensitivity. The latest experiment we are developing will have 100 times more sensitivity than the previous leading experiment. A nonzero nEDM could, among other consequences, explain the presence of more matter than antimatter in the universe. To measure the nEDM with high accuracy, it is necessary to have a very uniform magnetic field inside the detector since non-uniformities can create false signals via the geometric phase effect. One way to improve field uniformity is to add superconducting lead endcaps to the detector, which constrain the fields at their surfaces to be parallel to them. Here, we test how the endcaps improve field uniformity by measuring the magnetic field at various points in a 1/3-scale experimental volume, inferring what the field must be at all other points, and calculating gradients in the field. This knowledge could help guide further steps needed to improve field uniformity and characterize limitations to the sensitivity of nEDM measurements for the full-scale experiment. Rose Hills Foundation, National Science Foundation Grant 1506459, and Department of Energy.

Ion and Electron Energization in Guide Field Reconnection Outflows with Kinetic Riemann Simulations and Parallel Shock Simulations

NASA Astrophysics Data System (ADS)

Zhang, Q.; Drake, J. F.; Swisdak, M.

2017-12-01

How ions and electrons are energized in magnetic reconnection outflows is an essential topic throughout the heliosphere. Here we carry out guide field PIC Riemann simulations to explore the ion and electron energization mechanisms far downstream of the x-line. Riemann simulations, with their simple magnetic geometry, facilitate the study of the reconnection outflow far downstream of the x-line in much more detail than is possible with conventional reconnection simulations. We find that the ions get accelerated at rotational discontinuities, counter stream, and give rise to two slow shocks. We demonstrate that the energization mechanism at the slow shocks is essentially the same as that of parallel electrostatic shocks. Also, the electron confining electric potential at the slow shocks is driven by the counterstreaming beams, which tend to break the quasi-neutrality. Based on this picture, we build a kinetic model to self consistently predict the downstream ion and electron temperatures. Additional explorations using parallel shock simulations also imply that in a very low beta(0.001 0.01 for a modest guide field) regime, electron energization will be insignificant compared to the ion energization. Our model and the parallel shock simulations might be used as simple tools to understand and estimate the energization of ions and electrons and the energy partition far downstream of the x-line.

Laser-sodium interaction for the polychromatic laser guide star project

NASA Astrophysics Data System (ADS)

Bellanger, Veronique; Petit, Alain D.

2002-02-01

We developed a code aimed at determining the laser parameters leading to the maximum return flux of photons at 0.33 micrometers for a polychromatic sodium Laser Guide Star. This software relies upon a full 48-level collisionless and magnetic-field-free density-matrix description of the hyperfine structure of Na and includes Doppler broadening and Zeeman degeneracy. Experimental validation of BEACON was conducted on the SILVA facilities and will also be discussed in this paper.

Atomic layer deposition of titanium oxide films on As-synthesized magnetic Ni particles: Magnetic and safety properties

NASA Astrophysics Data System (ADS)

Uudeküll, Peep; Kozlova, Jekaterina; Mändar, Hugo; Link, Joosep; Sihtmäe, Mariliis; Käosaar, Sandra; Blinova, Irina; Kasemets, Kaja; Kahru, Anne; Stern, Raivo; Tätte, Tanel; Kukli, Kaupo; Tamm, Aile

2017-05-01

Spherical nickel particles with size in the range of 100-400 nm were synthesized by non-aqueous liquid phase benzyl alcohol method. Being developed for magnetically guided biomedical applications, the particles were coated by conformal and antimicrobial thin titanium oxide films by atomic layer deposition. The particles retained their size and crystal structure after the deposition of oxide films. The sensitivity of the coated particles to external magnetic fields was increased compared to that of the uncoated powder. Preliminary toxicological investigations on microbial cells and small aquatic crustaceans revealed non-toxic nature of the synthesized particles.

Stemless ball valve

NASA Technical Reports Server (NTRS)

Burgess, Kevin (Inventor); Yakos, David (Inventor); Walthall, Bryan (Inventor)

2012-01-01

A stemless ball valve comprising: a right flange; left flange; ball with an axis pin and two travel pins; ball seal on either side of the ball; guide sleeve with inner walls comprising two channels; cartridge guide holder; inner magnetic cartridge; and outer magnetic cartridge. The ball is situated inside of the guide sleeve, and a travel pin is located in each of the two channels. The guide sleeve is situated inside of the cartridge guide holder, which is located adjacent to and outside of the inner magnetic cartridge and secured to the inner magnetic cartridge such that when the inner magnetic cartridge rotates, the cartridge guide holder also rotates. The cartridge guide holder is secured to the guide sleeve such that when the cartridge guide holder rotates, the travel pins move within the channels in the inner walls of the guide sleeve, thereby causing the ball to rotate.

Simulation of the 3-D Evolution of Electron Scale Magnetic Reconnection - Motivated by Laboratory Experiments Predictions for MMS

NASA Astrophysics Data System (ADS)

Buechner, J.; Jain, N.; Sharma, A.

2013-12-01

The four s/c of the Magnetospheric Multiscale (MMS) mission, to be launched in 2014, will use the Earth's magnetosphere as a laboratory to study the microphysics of three fundamental plasma processes. One of them is magnetic reconnection, an essentially multi-scale process. While laboratory experiments and past theoretical investigations have shown that important processes necessary to understand magnetic reconnection take place at electron scales the MMS mission for the first time will be able to resolve these scales by in space observations. For the measurement strategy of MMS it is important to make specific predictions of the behavior of current sheets with a thickness of the order of the electron skin depth which play an important role in the evolution of collisionless magnetic reconnection. Since these processes are highly nonlinear and non-local numerical simulation is needed to specify the current sheet evolution. Here we present new results about the nonlinear evolution of electron-scale current sheets starting from the linear stage and using 3-D electron-magnetohydrodynamic (EMHD) simulations. The growth rates of the simulated instabilities compared well with the growth rates obtained from linear theory. Mechanisms and conditions of the formation of flux ropes and of current filamentation will be discussed in comparison with the results of fully kinetic simulations. In 3D the X- and O-point configurations of the magnetic field formed in reconnection planes alternate along the out-of-reconnection-plane direction with the wavelength of the unstable mode. In the presence of multiple reconnection sites, the out-of-plane magnetic field can develop nested structure of quadrupoles in reconnection planes, similar to the 2-D case, but now with variations in the out-of-plane direction. The structures of the electron flow and magnetic field in 3-D simulations will be compared with those in 2-D simulations to discriminate the essentially 3D features. We also discuss the influence of guide fields, as in the magnetopause case and show how the 3-D evolution of an electron current sheet is influenced the strength of the guide field. This is unlike the 2-D case where reconnection takes place only in a plane. This work was partially funded by the Max-Planck/Princeton Center for Plasma Physics and the National Science Foundation.

The role of three-dimensional transport in driving enhanced electron acceleration during magnetic reconnection

NASA Astrophysics Data System (ADS)

Dahlin, J. T.; Drake, J. F.; Swisdak, M.

2017-09-01

Magnetic reconnection is an important driver of energetic particles in many astrophysical phenomena. Using kinetic particle-in-cell simulations, we explore the impact of three-dimensional reconnection dynamics on the efficiency of particle acceleration. In two-dimensional systems, Alfvénic outflows expel energetic electrons into flux ropes where they become trapped and disconnected from acceleration regions. However, in three-dimensional systems these flux ropes develop an axial structure that enables particles to leak out and return to acceleration regions. This requires a finite guide field so that particles may move quickly along the flux rope axis. We show that greatest energetic electron production occurs when the guide field is of the same order as the reconnecting component: large enough to facilitate strong transport, but not so large as to throttle the dominant Fermi mechanism responsible for efficient electron acceleration. This suggests a natural explanation for the envelope of electron acceleration during the impulsive phase of eruptive flares.

Simulation of a gigawatt level Ku-band overmoded Cerenkov type oscillator operated at low guiding magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Hua; Shu, Ting, E-mail: mrtingshu@qq.com; Ju, Jinchuan

2014-03-15

We present the simulation results of a Ku-band overmoded Cerenkov type high power microwave oscillator. A guiding magnetic field as low as 0.6 T has been operated in the device. Overmoded slow wave structures with gradually tapered vanes are used in order to increase power capacity and the efficiency of beam-wave interaction. The drift cavity is adopted to enhance the beam-wave interaction of the device. After numerical optimization, the designed generator with an output microwave power of 1.2 GW, a frequency of 13.8 GHz, and a power conversion efficiency as high as 38% can be achieved, when the diode voltage and currentmore » are, respectively, 540 kV and 5.8 kA. The power compositions of TM{sub 0n} modes of the output microwave have been analyzed, the results of which show that TM{sub 01} mode takes over almost 95% of the power proportion.« less

Driving magnetic turbulence using flux ropes in a moderate guide field linear system

NASA Astrophysics Data System (ADS)

Brookhart, Matthew I.; Stemo, Aaron; Waleffe, Roger; Forest, Cary B.

2017-12-01

We present a series of experiments on novel, line-tied plasma geometries as a study of the generation of chaos and turbulence in line-tied systems. Plasma production and the injection scale for magnetic energy is provided by spatially discrete plasma guns that inject both plasma and current. The guns represent a technique for controlling the injection scale of magnetic energy. A two-dimensional (2-D) array of magnetic probes provides spatially resolved time histories of the magnetic fluctuations at a single cross-section of the experimental cylinder, allowing simultaneous spatial measurements of chaotic and turbulent behaviour. The first experiment shows chaotic fluctuations and self-organization in a hollow-current line-tied screw pinch. These dynamics is modulated primarily by the applied magnetic field and weakly by the plasma current and safety factor. The second experiment analyses the interactions of multiple line-tied flux ropes. The flux ropes all exhibit chaotic behaviour, and under certain conditions develop an inverse cascade to larger scales and a turbulent inertial range with magnetic energy ( ) related to perpendicular wave number ( \\bot $ ) as \\bot -2.5\\pm 0.5$ .

Interfacial exchange coupling and magnetization reversal in perpendicular [Co/Ni]N/TbCo composite structures.

PubMed

Tang, M H; Zhang, Zongzhi; Tian, S Y; Wang, J; Ma, B; Jin, Q Y

2015-06-15

Interfacial exchange coupling and magnetization reversal characteristics in the perpendicular heterostructures consisting of an amorphous ferrimagnetic (FI) TbxCo(100-x) alloy layer exchange-coupled with a ferromagnetic (FM) [Co/Ni]N multilayer have been investigated. As compared with pure TbxCo(100-x) alloy, the magnetization compensation composition of the heterostructures shift to a higher Tb content, implying Co/Ni also serves to compensate the Tb moment in TbCo layer. The net magnetization switching field Hc⊥ and interlayer interfacial coupling field Hex, are not only sensitive to the magnetization and thickness of the switched TbxCo(100-x) or [Co/Ni]N layer, but also to the perpendicular magnetic anisotropy strength of the pinning layer. By tuning the layer structure we achieve simultaneously both large Hc⊥ = 1.31 T and Hex = 2.19 T. These results, in addition to the fundamental interest, are important to understanding of the interfacial coupling interaction in the FM/FI heterostructures, which could offer the guiding of potential applications in heat-assisted magnetic recording or all-optical switching recording technique.

Controlling Magnetotactic Bacteria through an Integrated Nanofabricated Metallic Island and Optical Microscope Approach

PubMed Central

González, Lina M.; Ruder, Warren C.; Leduc, Philip R.; Messner, William C.

2014-01-01

Herein, we demonstrate the control of magnetotactic bacteria through the application of magnetic field gradients with real-time visualization. We accomplish this control by integrating a pair of macroscale Helmholtz coils and lithographically fabricated nanoscale islands composed of permalloy (Ni80Fe20). This system enabled us to guide and steer amphitrichous Magnetospirillum magneticum strain AMB-1 to specific location via magnetic islands. The geometries of the islands allowed us to have control over the specific magnetic field gradients on the bacteria. We estimate that magnetotactic bacteria located less than 1 μm from the edge of a diamond shaped island experience a maximum force of approximately 34 pN, which engages the bacteria without trapping them. Our system could be useful for a variety of applications including magnetic fabrication, self-assembly, and probing the sensing apparatus of magnetotactic bacteria. PMID:24553101

Investigation of magnetically smart films applied to correct the surface profile of light weight X-ray optics in two directions

NASA Astrophysics Data System (ADS)

Wang, Xiaoli; Yao, Youwei; Cao, Jian; Vaynman, Semyon; Graham, Michael E.; Liu, Tianchen; Ulmer, M. P.

2015-09-01

Our goal is to improve initially fabricated X-ray optics figures by applying a magnetic field to drive a magnetic smart material (MSM) coating on the non-reflecting side of the mirror. The consequent deformation of the surface should be three-dimensional. Here we will report on the results of working with a glass sample of 50x50x0.2 mm that has been coated with MSMs. The coated glass can be deformed in 3 dimensions and its surface profile was measured under our Zygo NewView white light interferometer (WLI). The driving magnetic field was produced via a pseudo-magnetic write head made up of two permanent magnet posts. The magnet posts were moved about the bottom of the glass sample with a 3-d computer controlled translation stage. The system allowed four degrees of freedom of motion, i.e., up and down, side to side, back and forth, and rotation of the posts (3.175 mm diameter) about the vertical axis to allow us to change the orientation of the magnetic field in the (horizontal) plane of the sample. We established a finite element analysis (FEA) model to predict deformations and compare with the observed results in order to guide the application of the magnetically controlled MSMs to improve the future X-ray optics figures.

Washington Geothermal Play Fairway Analysis Data From Potential Field Studies

DOE Data Explorer

Anderson, Megan; Ritzinger, Brent; Glen, Jonathan; Schermerhorn, William

2017-12-20

A recent study which adapts play fairway analysis (PFA) methodology to assess geothermal potential was conducted at three locations (Mount Baker, Mount St. Helens seismic zone, and Wind River valley) along the Washington Cascade Range (Forson et al. 2017). Potential field (gravity and magnetic) methods which can detect subsurface contrasts in physical properties, provides a means for mapping and modeling subsurface geology and structure. As part of the WA-Cascade PFA project, we performed potential field studies by collecting high-resolution gravity and ground-magnetic data, and rock property measurements to (1) identify and constrain fault geometries (2) constrain subsurface lithologic distribution (3) study fault interactions (4) identify areas favorable to hydrothermal flow, and ultimately (5) guide future geothermal exploration at each location.

Magnetically guided release of ciprofloxacin from superparamagnetic polymer nanocomposites.

PubMed

Gupta, Rashmi; Bajpai, A K

2011-01-01

Tailored with superparamagnetic properties the magnetic nanocomposites have been thoroughly investigated in recent past because of their potential applications in the fields of biomedicine and bioengineering such as protein detection, magnetic targeted drug carriers, bioseparation, magnetic resonance imaging contrast agents and hyperthermia. Magnetic drug targeting has come up as a safe and effective drug-delivery technology, i.e., with the least amount of magnetic particles a maximum of drug may be easily administered and transported to the site of choice. In the present work novel magnetic drug-targeting carriers consisting of magnetic nanoparticles encapsulated within a smart polymer matrix with potential of controlled drug release is described. To make such magnetic polymeric drug-delivery systems, both the magnetic nanoparticles and antibiotic drug (ciprofloxacin) were incorporated into the hydrogel. The controlled release process and release profiles were investigated as a function of experimental protocols such as percent loading of drug, chemical composition of the nanocomposite, pH of release media and strength of magnetic field on the release profiles. The structure, morphology and compositions of magnetic hydrogel nanocomposites were characterized by FT-IR, TEM, XRD and VSM techniques. It was found that magnetic nanocomposites were biocompatible and superparamagnetic in nature and could be used as a smart drug carrier for controlled and targeted drug delivery.

Image-guided regularization level set evolution for MR image segmentation and bias field correction.

PubMed

Wang, Lingfeng; Pan, Chunhong

2014-01-01

Magnetic resonance (MR) image segmentation is a crucial step in surgical and treatment planning. In this paper, we propose a level-set-based segmentation method for MR images with intensity inhomogeneous problem. To tackle the initialization sensitivity problem, we propose a new image-guided regularization to restrict the level set function. The maximum a posteriori inference is adopted to unify segmentation and bias field correction within a single framework. Under this framework, both the contour prior and the bias field prior are fully used. As a result, the image intensity inhomogeneity can be well solved. Extensive experiments are provided to evaluate the proposed method, showing significant improvements in both segmentation and bias field correction accuracies as compared with other state-of-the-art approaches. Copyright © 2014 Elsevier Inc. All rights reserved.

Collisionless dissipation processes in quasi-parallel shocks. [in solar wind

NASA Technical Reports Server (NTRS)

Quest, K. B.; Forslund, D. W.; Brackbill, J. U.; Lee, K.

1983-01-01

The evolution of collisionless, quasi-parallel shocks (the angle between the shock normal and the upstream magnetic field being less than 45 deg) is examined using two dimensional particle simulations. Reflected ions upstream from the shock are observed with average guiding center velocity and gyrational energy which agree well with the prediction of simple specular reflection. Strong ion heating through the shock ramp is apparently caused by large amplitude whistler turbulence. A flux of suprathermal electrons is also the magnetic field direction. Much stronger ion heating occurs in the shock than electron heating. The relevance of this work to the earth's bow shock is discussed.

Computational modeling of magnetic particle margination within blood flow through LAMMPS

NASA Astrophysics Data System (ADS)

Ye, Huilin; Shen, Zhiqiang; Li, Ying

2017-11-01

We develop a multiscale and multiphysics computational method to investigate the transport of magnetic particles as drug carriers in blood flow under influence of hydrodynamic interaction and external magnetic field. A hybrid coupling method is proposed to handle red blood cell (RBC)-fluid interface (CFI) and magnetic particle-fluid interface (PFI), respectively. Immersed boundary method (IBM)-based velocity coupling is used to account for CFI, which is validated by tank-treading and tumbling behaviors of a single RBC in simple shear flow. While PFI is captured by IBM-based force coupling, which is verified through movement of a single magnetic particle under non-uniform external magnetic field and breakup of a magnetic chain in rotating magnetic field. These two components are seamlessly integrated within the LAMMPS framework, which is a highly parallelized molecular dynamics solver. In addition, we also implement a parallelized lattice Boltzmann simulator within LAMMPS to handle the fluid flow simulation. Based on the proposed method, we explore the margination behaviors of magnetic particles and magnetic chains within blood flow. We find that the external magnetic field can be used to guide the motion of these magnetic materials and promote their margination to the vascular wall region. Moreover, the scaling performance and speedup test further confirm the high efficiency and robustness of proposed computational method. Therefore, it provides an efficient way to simulate the transport of nanoparticle-based drug carriers within blood flow in a large scale. The simulation results can be applied in the design of efficient drug delivery vehicles that optimally accumulate within diseased tissue, thus providing better imaging sensitivity, therapeutic efficacy and lower toxicity.

Magnetic charge distribution and stray field landscape of asymmetric néel walls in a magnetically patterned exchange bias layer system

NASA Astrophysics Data System (ADS)

Zingsem, Norbert; Ahrend, Florian; Vock, Silvia; Gottlob, Daniel; Krug, Ingo; Doganay, Hatice; Holzinger, Dennis; Neu, Volker; Ehresmann, Arno

2017-12-01

The 3D stray field landscape above an exchange bias layer system with engineered domain walls has been fully characterized by quantitative magnetic force microscopy (qMFM) measurements. This method is based on a complete quantification of the MFM tip’s imaging properties and the subtraction of its contribution from the measured MFM data by deconvolution in Fourier space. The magnetically patterned Ir17Mn83/Co70Fe30-exchange-bias-multilayers have been designed to contain asymmetric head-to-head (hh)/tail-to-tail (tt) Néel walls between domains of different magnetic anisotropies for potential use in guided particle transport. In the current application, qMFM reveals the effective magnetic charge profile on the surface of the sample—with high spatial resolution and in an absolute quantitative manner. These data enable to calculate the magnetostatic potential and the full stray field landscape above the sample surface. It has been successfully tested against: (i) micromagnetic simulations of the magnetization structure of a comparable exchange-bias layer system, (ii) measurements of the magnetization profile across the domain boundary with x-ray photoemission electron microscopy, and (iii) direct stray field measurements obtained by scanning Hall probe microscopy at elevated scan heights. This approach results in a quantitative determination of the stray field landscape at close distances to the sample surface, which will be of importance for remote magnetic particle transport applications in lab-on-a-chip devices. Furthermore, the highly resolving and quantitative MFM approach reveals details of the domain transition across the artificially structured phase boundary, which have to be attributed to a continuous change in the materials parameters across this boundary, rather than an abrupt one.

Resonant circuit which provides dual-frequency excitation for rapid cycling of an electromagnet

DOEpatents

Praeg, W.F.

1982-03-09

Disclosed is a novel ring-magnet control circuit that permits synchrotron repetition rates much higher than the frequency of the sinusoidal guide field of the ring magnet during particle acceleration. The control circuit generates sinusoidal excitation currents of different frequencies in the half waves. During radio-frequency acceleration of the synchrotron, the control circuit operates with a lower frequency sine wave and, thereafter, the electromagnets are reset with a higher-frequency half sine wave.

Magnetic pinning in a superconducting film by a ferromagnetic layer with stripe domains

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mancusi, D.; Di Giorgio, C.; Bobba, F.

2014-10-31

A magnetic study of superconductor/ferromagnet bilayers was performed by hysteresis loops and temperature-dependent magnetization measurements. The superconductor/ferromagnet bilayers consist of a Nb film deposited on a Py film with weak perpendicular magnetic anisotropy. By comparing the temperature-dependent magnetization data obtained on samples with different ferromagnetic layer thickness, a decrease of the magnetic pinning with increasing thickness of the ferromagnetic layer has been found. This is confirmed by the reduction of the Nb film critical current density at low fields extracted by using the magnetic irreversibility of the hysteresis loops. As the ferromagnetic layer exhibits a magnetic structure with stripe domains,more » whose width increases for increasing thickness as observed by magnetic force microscopy (MFM) measurements, we relate the reduction of the superconducting critical current in samples with thicker ferromagnetic layers to a weaker interaction between the vortices guided by the underlying magnetic template.« less

Magnetofluidic concentration and separation of non-magnetic particles using two magnet arrays

PubMed Central

Hejazian, Majid

2016-01-01

The present paper reports the use of diluted ferrofluid and two arrays of permanent magnets for the size-selective concentration of non-magnetic particles. The micro magnetofluidic device consists of a straight channels sandwiched between two arrays of permanent magnets. The permanent magnets create multiple capture zones with minimum magnetic field strength along the channel. The complex interaction between magnetic forces and hydrodynamic force allows the device to operate in different regimes suitable for concentration of non-magnetic particles with small difference in size. Our experimental results show that non-magnetic particles with diameters of 3.1 μm and 4.8 μm can be discriminated and separated with this method. The results from this study could be used as a guide for the design of size-sensitive separation devices for particle and cell based on negative magnetophoresis. PMID:27478527

Low-dose magnetic-field-immune biplanar fluoroscopy for neurosurgery

NASA Astrophysics Data System (ADS)

Ramos, P. A.; Lawson, Michael A.; Wika, Kevin G.; Allison, Stephen W.; Quate, E. G.; Molloy, J. A.; Ritter, Rogers C.; Gilles, George T.

1991-07-01

The imaging chain of a bi-planar fluoroscopic system is described for a new neurosurgical technique: the Video Tumor Fighter (VTF). The VTF manipulates a small intracranially implanted magnet, called a thermoseed, by a large external magnetic field gradient. The thermoseed is heated by rf-induction to kill proximal tumor cells. For accurately guiding the seed through the brain, the x-ray tubes are alternately pulsed up to four times per second, each for as much as two hours. Radio-opaque reference markers, attached to the skull, enable the thermoseed's three dimensional position to be determined and then projected onto a displayed MRI brain scan. The imaging approach, similar to systems at the University of Arizona and the Mayo Clinic, includes a 20 cm diameter phosphor screen viewed by a proximity focused microchannel plate image intensifier coupled via fiberoptic taper to a solid state camera. The most important performance specifications are magnetic field immunity and, due to the procedure duration, low dosage per image. A preliminary arrangement designed in the laboratories yielded usable images at approximately 100 (mu) R exposure per frame. In this paper, the results of a series of studies of the effects of magnetic fields on microchannel plate image intensifiers used in the image detection chain are presented.

The extent of power-law energy spectra in collisionless relativistic magnetic reconnection in pair plasma

DOE PAGES

Werner, G. R.; Uzdensky, D. A.; Cerutti, B.; ...

2015-12-30

Using two-dimensional particle-in-cell simulations, we characterize the energy spectra of particles accelerated by relativistic magnetic reconnection (without guide field) in collisionless electron–positron plasmas, for a wide range of upstream magnetizations σ and system sizes L. The particle spectra are well-represented by a power lawmore » $${\\gamma }^{-\\alpha }$$, with a combination of exponential and super-exponential high-energy cutoffs, proportional to σ and L, respectively. As a result, for large L and σ, the power-law index α approaches about 1.2.« less

Comparison of two fiber-optical temperature measurement systems in magnetic fields up to 9.4 Tesla.

PubMed

Buchenberg, Waltraud B; Dadakova, Tetiana; Groebner, Jens; Bock, Michael; Jung, Bernd

2015-05-01

Precise temperature measurements in the magnetic field are indispensable for MR safety studies and for temperature calibration during MR-guided thermotherapy. In this work, the interference of two commonly used fiber-optical temperature measurement systems with the static magnetic field B0 was determined. Two fiber-optical temperature measurement systems, a GaAs-semiconductor and a phosphorescent phosphor ceramic, were compared for temperature measurements in B0 . The probes and a glass thermometer for reference were placed in an MR-compatible tube phantom within a water bath. Temperature measurements were carried out at three different MR systems covering static magnetic fields up to B0  = 9.4T, and water temperatures were changed between 25°C and 65°C. The GaAs-probe significantly underestimated absolute temperatures by an amount related to the square of B0 . A maximum difference of ΔT = -4.6°C was seen at 9.4T. No systematic temperature difference was found with the phosphor ceramic probe. For both systems, the measurements were not dependent on the orientation of the sensor to B0 . Temperature measurements with the phosphor ceramic probe are immune to magnetic fields up to 9.4T, whereas the GaAs-probes either require a recalibration inside the MR system or a correction based on the square of B0. © 2014 Wiley Periodicals, Inc.

Magnetic Navigation in Sea Turtles: Insights from Secular Variation

NASA Astrophysics Data System (ADS)

Putman, N. F.; Lohmann, K.

2011-12-01

Sea turtles are iconic migrants that posses a sensitive magnetic-sense that guides their long-distance movements in a variety of contexts. In the first few hours after hatching turtles use the magnetic field to maintain an offshore compass heading to reach deeper water, out of the reach of nearshore predators. Young turtles engage in directed swimming in response to regional magnetic fields that exist along their transoceanic migratory path. Older turtles also use magnetic information to relocate foraging sites and islands used for nesting after displacement. Numerous hypotheses have been put forth to explain how magnetic information functions in these movements, however, there is little consensus among animal navigation researchers. A particular vexing issue is how magnetic navigation can function under the constraints of the constant, gradual shifting of the earth's magnetic field (secular variation). Here, I present a framework based on models of recent geomagnetic secular variation to explore several navigational mechanisms proposed for sea turtles. I show that while examination of secular variation likely falsifies some hypothetical navigational strategies, it provides key insights into the selective pressures that could maintain other navigational mechanisms. Moreover, examination of secular variation's influence on the navigational precision in reproductive migrations of sea turtles offers compelling explanations for the population structure along sea turtle nesting beaches as well as spatiotemporal variation in nesting turtle abundance.

Large-scale particle acceleration by magnetic reconnection during solar flares

NASA Astrophysics Data System (ADS)

Li, X.; Guo, F.; Li, H.; Li, G.; Li, S.

2017-12-01

Magnetic reconnection that triggers explosive magnetic energy release has been widely invoked to explain the large-scale particle acceleration during solar flares. While great efforts have been spent in studying the acceleration mechanism in small-scale kinetic simulations, there have been rare studies that make predictions to acceleration in the large scale comparable to the flare reconnection region. Here we present a new arrangement to study this problem. We solve the large-scale energetic-particle transport equation in the fluid velocity and magnetic fields from high-Lundquist-number MHD simulations of reconnection layers. This approach is based on examining the dominant acceleration mechanism and pitch-angle scattering in kinetic simulations. Due to the fluid compression in reconnection outflows and merging magnetic islands, particles are accelerated to high energies and develop power-law energy distributions. We find that the acceleration efficiency and power-law index depend critically on upstream plasma beta and the magnitude of guide field (the magnetic field component perpendicular to the reconnecting component) as they influence the compressibility of the reconnection layer. We also find that the accelerated high-energy particles are mostly concentrated in large magnetic islands, making the islands a source of energetic particles and high-energy emissions. These findings may provide explanations for acceleration process in large-scale magnetic reconnection during solar flares and the temporal and spatial emission properties observed in different flare events.

Design of a magnetic shielding system for the time of flight enhanced diagnostics neutron spectrometer at Experimental Advanced Superconducting Tokamak

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cui, Z. Q.; Chen, Z. J.; Xie, X. F.

2014-11-15

The novel neutron spectrometer TOFED (Time of Flight Enhanced Diagnostics), comprising 90 individual photomultiplier tubes coupled with 85 plastic scintillation detectors through light guides, has been constructed and installed at Experimental Advanced Superconducting Tokamak. A dedicated magnetic shielding system has been constructed for TOFED, and is designed to guarantee the normal operation of photomultiplier tubes in the stray magnetic field leaking from the tokamak device. Experimental measurements and numerical simulations carried out employing the finite element method are combined to optimize the design of the magnetic shielding system. The system allows detectors to work properly in an external magnetic fieldmore » of 200 G.« less

Navigation concepts for MR image-guided interventions.

PubMed

Moche, Michael; Trampel, Robert; Kahn, Thomas; Busse, Harald

2008-02-01

The ongoing development of powerful magnetic resonance imaging techniques also allows for advanced possibilities to guide and control minimally invasive interventions. Various navigation concepts have been described for practically all regions of the body. The specific advantages and limitations of these concepts largely depend on the magnet design of the MR scanner and the interventional environment. Open MR scanners involve minimal patient transfer, which improves the interventional workflow and reduces the need for coregistration, ie, the mapping of spatial coordinates between imaging and intervention position. Most diagnostic scanners, in contrast, do not allow the physician to guide his instrument inside the magnet and, consequently, the patient needs to be moved out of the bore. Although adequate coregistration and navigation concepts for closed-bore scanners are technically more challenging, many developments are driven by the well-known capabilities of high-field systems and their better economic value. Advanced concepts such as multimodal overlays, augmented reality displays, and robotic assistance devices are still in their infancy but might propel the use of intraoperative navigation. The goal of this work is to give an update on MRI-based navigation and related techniques and to briefly discuss the clinical experience and limitations of some selected systems. (Copyright) 2008 Wiley-Liss, Inc.

Approaches to creating and controlling motion in MRI.

PubMed

Fischer, Gregory S; Cole, Gregory; Su, Hao

2011-01-01

Magnetic Resonance Imaging (MRI) can provide three dimensional (3D) imaging with excellent resolution and sensitivity making it ideal for guiding and monitoring interventions. The development of MRI-compatible interventional devices is complicated by factors including: the high magnetic field strength, the requirement that such devices should not degrade image quality, and the confined physical space of the scanner bore. Numerous MRI guided actuated devices have been developed or are currently being developed utilizing piezoelectric actuators as their primary means of mechanical energy generation to enable better interventional procedure performance. While piezoelectric actuators are highly desirable for MRI guided actuation for their precision, high holding force, and non-magnetic operation they are often found to cause image degradation on a large enough to scale to render live imaging unusable. This paper describes a newly developed piezoelectric actuator driver and control system designed to drive a variety of both harmonic and non-harmonic motors that has been demonstrated to be capable of operating both harmonic and non-harmonic piezoelectric actuators with less than 5% SNR loss under closed loop control. The proposed system device allows for a single controller to control any supported actuator and feedback sensor without any physical hardware changes.

A type of cylindrical Hall thruster with a magnetically insulated anode

NASA Astrophysics Data System (ADS)

Yongjie, Ding; Yu, Xu; Wuji, Peng; Liqiu, Wei; Hongbo, Su; Hezhi, Sun; Peng, Li; Hong, Li; Daren, Yu

2017-04-01

In this paper, a type of magnetically insulated anode structure is proposed for the design of a low-power cylindrical Hall thruster. The magnetic field distribution in the channel is guided by the magnetically insulated anode, altering the intersection status of the magnetic field line passing through the anode and wall. Experimental and simulation results show that a high potential is formed near the wall by the magnetically insulated anode. As the ionization moves towards the outlet, the energy and flux of the ions bombarding the channel wall can be reduced effectively. Due to the reduction in the bombardment of the wall from high-energy ions, the thrust and specific impulse greatly increase compared with those of the non-magnetically insulated anode. For anode mass flow rates of 0.3 and 0.35 mg s-1 and discharge voltages in the 100-200 V range, the thrust can be increased by more than 33% and the anode efficiency can be improved by more than 7%. Meanwhile, the length of the sputtering area is clearly reduced. The starting position of the sputtering area is in front of the magnetic pole, which can effectively prolong the service life of the thruster.

Running Performance of a Pinning-Type Superconducting Magnetic Levitation Guide

NASA Astrophysics Data System (ADS)

Okano, M.; Iwamoto, T.; Furuse, M.; Fuchino, S.; Ishii, I.

2006-06-01

A pinning-type superconducting magnetic levitation guide with bulk high-Tc superconductors was studied for use as a goods transportation system, an energy storage system, etc. A superconducting magnetic levitation running test apparatus with a circular track of ca. 38 m length, 12 m diameter, which comprises the magnetic rail constituted by Nd-B-Fe rare-earth permanent magnets and steel plates, was manufactured to examine loss and high-speed performance of the magnetic levitation guide. Running tests were conducted in air. These tests clarify that a vehicle supported by a superconducting magnetic levitation guide runs stably at speeds greater than 42 km/h above the circular track.

High field gradient particle accelerator

DOEpatents

Nation, John A.; Greenwald, Shlomo

1989-01-01

A high electric field gradient electron accelerator utilizing short duration, microwave radiation, and capable of operating at high field gradients for high energy physics applications or at reduced electric field gradients for high average current intermediate energy accelerator applications. Particles are accelerated in a smooth bore, periodic undulating waveguide, wherein the period is so selected that the particles slip an integral number of cycles of the r.f. wave every period of the structure. This phase step of the particles produces substantially continuous acceleration in a traveling wave without transverse magnetic or other guide means for the particle.

An industrial design solution for integrating NMR magnetic field sensors into an MRI scanner.

PubMed

Kennedy, Michael; Lee, Yoojin; Nagy, Zoltan

2018-08-01

Neuroimaging research relies on the skills of increasingly multidisciplinary individuals and often requires the installation and use of additional home-built or third-party equipment. The purpose of the present work was the safe, ergonomic, durable, and aesthetically pleasing installation of magnetic field monitoring equipment into a scanner, while keeping the setup compatible with standard operating procedures. An extensive set of steps was required to design a 3D printed solution to install a magnetic field camera into the eight-channel head coil of a 3T MRI scanner. First, the outer surface of the plastic coil housing was recreated into a 3D model, and the installation of the magnetic field sensors around this 3D model was performed in a virtual environment. The 3D printed solution was then assembled and tested for safety, reproducible performance, and image quality. The 3D printed solution holds the probes in stable positions and guides the necessary cables in an organized fashion and away from the volunteer. Assembly is easy and the solution is ergonomic, durable, and safe. We did not find excessive heating in the 3D printed parts, nor in the electronics, that they help to incorporate. The material used interferes minimally with transmit B1+ field. The design met all of the boundary conditions for a durable, safe, cost-effective, attractive, and functional installation. This work will provide the basis for installing the magnetic field sensors into other available head coils, and for designing the experimental setup for projects with varying experimental requirements. Magn Reson Med 80:833-839, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

Technical design and commissioning of the KATRIN large-volume air coil system

NASA Astrophysics Data System (ADS)

Erhard, M.; Behrens, J.; Bauer, S.; Beglarian, A.; Berendes, R.; Drexlin, G.; Glück, F.; Gumbsheimer, R.; Hergenhan, J.; Leiber, B.; Mertens, S.; Osipowicz, A.; Plischke, P.; Reich, J.; Thümmler, T.; Wandkowsky, N.; Weinheimer, C.; Wüstling, S.

2018-02-01

The KATRIN experiment is a next-generation direct neutrino mass experiment with a sensitivity of 0.2 eV (90% C.L.) to the effective mass of the electron neutrino. It measures the tritium β-decay spectrum close to its endpoint with a spectrometer based on the MAC-E filter technique. The β-decay electrons are guided by a magnetic field that operates in the mT range in the central spectrometer volume; it is fine-tuned by a large-volume air coil system surrounding the spectrometer vessel. The purpose of the system is to provide optimal transmission properties for signal electrons and to achieve efficient magnetic shielding against background. In this paper we describe the technical design of the air coil system, including its mechanical and electrical properties. We outline the importance of its versatile operation modes in background investigation and suppression techniques. We compare magnetic field measurements in the inner spectrometer volume during system commissioning with corresponding simulations, which allows to verify the system's functionality in fine-tuning the magnetic field configuration. This is of major importance for a successful neutrino mass measurement at KATRIN.

Confinement properties of tokamak plasmas with extended regions of low magnetic shear

NASA Astrophysics Data System (ADS)

Graves, J. P.; Cooper, W. A.; Kleiner, A.; Raghunathan, M.; Neto, E.; Nicolas, T.; Lanthaler, S.; Patten, H.; Pfefferle, D.; Brunetti, D.; Lutjens, H.

2017-10-01

Extended regions of low magnetic shear can be advantageous to tokamak plasmas. But the core and edge can be susceptible to non-resonant ideal fluctuations due to the weakened restoring force associated with magnetic field line bending. This contribution shows how saturated non-linear phenomenology, such as 1 / 1 Long Lived Modes, and Edge Harmonic Oscillations associated with QH-modes, can be modelled accurately using the non-linear stability code XTOR, the free boundary 3D equilibrium code VMEC, and non-linear analytic theory. That the equilibrium approach is valid is particularly valuable because it enables advanced particle confinement studies to be undertaken in the ordinarily difficult environment of strongly 3D magnetic fields. The VENUS-LEVIS code exploits the Fourier description of the VMEC equilibrium fields, such that full Lorenzian and guiding centre approximated differential operators in curvilinear angular coordinates can be evaluated analytically. Consequently, the confinement properties of minority ions such as energetic particles and high Z impurities can be calculated accurately over slowing down timescales in experimentally relevant 3D plasmas.

EVIDENCE OF MAGNETIC FIELD SWITCH-OFF IN COLLISIONLESS MAGNETIC RECONNECTION

DOE Office of Scientific and Technical Information (OSTI.GOV)

Innocenti, M. E.; Lapenta, G.; Goldman, M.

2015-09-10

The long-term evolution of large domain particle-in-cell simulations of collisionless magnetic reconnection is investigated following observations that show two possible outcomes for collisionless reconnection: toward a Petschek-like configuration or toward multiple X points. In the present simulation, a mixed scenario develops. At earlier time, plasmoids are emitted, disrupting the formation of Petschek-like structures. Later, an almost stationary monster plasmoid forms, preventing the emission of other plasmoids. A situation reminiscent of Petschek’s switch-off then ensues. Switch-off is obtained through a slow shock/rotational discontinuity compound structure. Two external slow shocks (SS) located at the separatrices reduce the in-plane tangential component of themore » magnetic field, but not to zero. Two transitions reminiscent of rotational discontinuities (RD) in the internal part of the exhaust then perform the final switch-off. Both the SS and the RD are characterized through analysis of their Rankine–Hugoniot jump conditions. A moderate guide field is used to suppress the development of the firehose instability in the exhaust.« less

Magnetic targeting as a strategy to enhance therapeutic effects of mesenchymal stromal cells.

PubMed

Silva, Luisa H A; Cruz, Fernanda F; Morales, Marcelo M; Weiss, Daniel J; Rocco, Patricia R M

2017-03-09

Mesenchymal stromal cells (MSCs) have been extensively investigated in the field of regenerative medicine. It is known that the success of MSC-based therapies depends primarily on effective cell delivery to the target site where they will secrete vesicles and soluble factors with immunomodulatory and potentially reparative properties. However, some lesions are located in sites that are difficult to access, such as the heart, spinal cord, and joints. Additionally, low MSC retention at target sites makes cell therapy short-lasting and, therefore, less effective. In this context, the magnetic targeting technique has emerged as a new strategy to aid delivery, increase retention, and enhance the effects of MSCs. This approach uses magnetic nanoparticles to magnetize MSCs and static magnetic fields to guide them in vivo, thus promoting more focused, effective, and lasting retention of MSCs at the target site. In the present review, we discuss the magnetic targeting technique, its principles, and the materials most commonly used; we also discuss its potential for MSC enhancement, and safety concerns that should be addressed before it can be applied in clinical practice.

Safety of High Speed Guided Ground Transportation Systems - EMF Exposure Environments Summary Reports

DOT National Transportation Integrated Search

1993-08-01

This paper presents an overview of American exposure assessments for electric and magnetic fields (EMF) in the frequency : range from 0 to 3 kHz. The exposure information available is very limited for all but a few occupations and sources of : EMF. M...

Detection of the Magnetospheric Emissions from Extrasolar Planets

NASA Astrophysics Data System (ADS)

Lazio, J.

2014-12-01

Planetary-scale magnetic fields are a window to a planet's interior and provide shielding of the planet's atmosphere. The Earth, Mercury, Ganymede, and the giant planets of the solar system all contain internal dynamo currents that generate planetary-scale magnetic fields. These internal dynamo currents arise from differential rotation, convection, compositional dynamics, or a combination of these. If coupled to an energy source, such as the incident kinetic or magnetic energy from the solar wind, a planet's magnetic field can produce electron cyclotron masers in its magnetic polar regions. The most well known example of this process is the Jovian decametric emission, but all of the giant planets and the Earth contain similar electron cyclotron masers within their magnetospheres. Extrapolated to extrasolar planets, the remote detection of the magnetic field of an extrasolar planet would provide a means of obtaining constraints on the thermal state, composition, and dynamics of its interior as well as improved understanding of the basic planetary dynamo process. The magnetospheric emissions from solar system planets and the discovery of extrasolar planets have motivated both theoretical and observational work on magnetospheric emissions from extrasolar planets. Stimulated by these advances, the W.M. Keck Institute for Space Studies hosted a workshop entitled "Planetary Magnetic Fields: Planetary Interiors and Habitability." I summarize the current observational status of searches for magnetospheric emissions from extrasolar planets, based on observations from a number of ground-based radio telescopes, and future prospects for ground-based studies. Using the solar system planetary magnetic fields as a guide, future space-based missions will be required to study planets with magnetic field strengths lower than that of Jupiter. I summarize mission concepts identified in the KISS workshop, with a focus on the detection of planetary electron cyclotron maser emission. The authors acknowledge ideas and advice from the participants in the "Planetary Magnetic Fields: Planetary Interiors and Habitability" workshop organized by the Keck Institute for Space Studies. Part of this research was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with NASA.

Development and Technology Transfer of the Syncro Blue Tube (Gabriel) Magnetically Guided Feeding Tube

DTIC Science & Technology

2017-06-01

other documentation. TITLE: Development and Technology Transfer of the Syncro Blue Tube (Gabriel) Magnetically Guided Feeding Tube REPORT DOCUMENTATION...TITLE AND SUBTITLE Development and Technology Transfer of the Syncro Blue Tube (Gabriel) Magnetically Guided Feeding Tube 5a. CONTRACT NUMBER W81XWH-09-2...Technical Abstract: Further Development and Technology Transfer of the Syncro BLUETUBE™ (Gabriel) Magnetically Guided Feeding Tube. New Primary

Magnetic Nanoparticles: Material Engineering and Emerging Applications in Lithography and Biomedicine

PubMed Central

Bao, Yuping; Wen, Tianlong; Samia, Anna Cristina S.; Khandhar, Amit; Krishnan, Kannan M.

2015-01-01

We present an interdisciplinary overview of material engineering and emerging applications of iron oxide nanoparticles. We discuss material engineering of nanoparticles in the broadest sense, emphasizing size and shape control, large-area self-assembly, composite/hybrid structures, and surface engineering. This is followed by a discussion of several non-traditional, emerging applications of iron oxide nanoparticles, including nanoparticle lithography, magnetic particle imaging, magnetic guided drug delivery, and positive contrast agents for magnetic resonance imaging. We conclude with a succinct discussion of the pharmacokinetics pathways of iron oxide nanoparticles in the human body –– an important and required practical consideration for any in vivo biomedical application, followed by a brief outlook of the field. PMID:26586919

Magnetic Nanoparticles: Material Engineering and Emerging Applications in Lithography and Biomedicine.

PubMed

Bao, Yuping; Wen, Tianlong; Samia, Anna Cristina S; Khandhar, Amit; Krishnan, Kannan M

2016-01-01

We present an interdisciplinary overview of material engineering and emerging applications of iron oxide nanoparticles. We discuss material engineering of nanoparticles in the broadest sense, emphasizing size and shape control, large-area self-assembly, composite/hybrid structures, and surface engineering. This is followed by a discussion of several non-traditional, emerging applications of iron oxide nanoparticles, including nanoparticle lithography, magnetic particle imaging, magnetic guided drug delivery, and positive contrast agents for magnetic resonance imaging. We conclude with a succinct discussion of the pharmacokinetics pathways of iron oxide nanoparticles in the human body -- an important and required practical consideration for any in vivo biomedical application, followed by a brief outlook of the field.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Werner, G. R.; Uzdensky, D. A.; Cerutti, B.

Using two-dimensional particle-in-cell simulations, we characterize the energy spectra of particles accelerated by relativistic magnetic reconnection (without guide field) in collisionless electron–positron plasmas, for a wide range of upstream magnetizations σ and system sizes L. The particle spectra are well-represented by a power lawmore » $${\\gamma }^{-\\alpha }$$, with a combination of exponential and super-exponential high-energy cutoffs, proportional to σ and L, respectively. As a result, for large L and σ, the power-law index α approaches about 1.2.« less

Magnetic Field Effects on Plasma Plumes

NASA Technical Reports Server (NTRS)

Ebersohn, F.; Shebalin, J.; Girimaji, S.; Staack, D.

2012-01-01

Here, we will discuss our numerical studies of plasma jets and loops, of basic interest for plasma propulsion and plasma astrophysics. Space plasma propulsion systems require strong guiding magnetic fields known as magnetic nozzles to control plasma flow and produce thrust. Propulsion methods currently being developed that require magnetic nozzles include the VAriable Specific Impulse Magnetoplasma Rocket (VASIMR) [1] and magnetoplasmadynamic thrusters. Magnetic nozzles are functionally similar to de Laval nozzles, but are inherently more complex due to electromagnetic field interactions. The two crucial physical phenomenon are thrust production and plasma detachment. Thrust production encompasses the energy conversion within the nozzle and momentum transfer to a spacecraft. Plasma detachment through magnetic reconnection addresses the problem of the fluid separating efficiently from the magnetic field lines to produce maximum thrust. Plasma jets similar to those of VASIMR will be studied with particular interest in dual jet configurations, which begin as a plasma loops between two nozzles. This research strives to fulfill a need for computational study of these systems and should culminate with a greater understanding of the crucial physics of magnetic nozzles with dual jet plasma thrusters, as well as astrophysics problems such as magnetic reconnection and dynamics of coronal loops.[2] To study this problem a novel, hybrid kinetic theory and single fluid magnetohydrodynamic (MHD) solver known as the Magneto-Gas Kinetic Method is used.[3] The solver is comprised of a "hydrodynamic" portion based on the Gas Kinetic Method and a "magnetic" portion that accounts for the electromagnetic behaviour of the fluid through source terms based on the resistive MHD equations. This method is being further developed to include additional physics such as the Hall effect. Here, we will discuss the current level of code development, as well as numerical simulation results

Well-Defined Peapod-like Magnetic Nanoparticles and Their Controlled Modification for Effective Imaging Guided Gene Therapy.

PubMed

Wang, Ranran; Hu, Yang; Zhao, Nana; Xu, Fu-Jian

2016-05-11

Due to their unique properties, one-dimensional (1D) magnetic nanostructures are of great significance for biorelated applications. A facile and straightforward strategy to fabricate 1D magnetic structure with special shapes is highly desirable. In this work, well-defined peapod-like 1D magnetic nanoparticles (Fe3O4@SiO2, p-FS) are readily synthesized by a facile method without assistance of any templates, magnetic string or magnetic field. There are few reports on 1D gene carriers based on Fe3O4 nanoparticles. BUCT-PGEA (ethanolamine-functionalized poly(glycidyl methacrylate) is subsequently grafted from the surface of p-FS nanoparticles by atom transfer radical polymerization to construct highly efficient gene vectors (p-FS-PGEA) for effective biomedical applications. Peapod-like p-FS nanoparticles were proven to largely improve gene transfection performance compared with ordinary spherical Fe3O4@SiO2 nanoparticles (s-FS). External magnetic field was also utilized to further enhance the transfection efficiency. Moreover, the as-prepared p-FS-PGEA gene carriers could combine the magnetic characteristics of p-FS to well achieve noninvasive magnetic resonance imaging (MRI). We show here novel and multifunctional magnetic nanostructures fabricated for biomedical applications that realized efficient gene delivery and real-time imaging at the same time.

Microwave Spectroscopy of a Single Permalloy Chiral Metamolecule on a Coplanar Waveguide

NASA Astrophysics Data System (ADS)

Kodama, Toshiyuki; Kusanagi, Yusaku; Okamoto, Satoshi; Kikuchi, Nobuaki; Kitakami, Osamu; Tomita, Satoshi; Hosoito, Nobuyoshi; Yanagi, Hisao

2018-05-01

We investigate the microwave spectroscopies of a micrometer-sized single permalloy (Py) chiral structure on coplanar waveguides (CPWs). Under an external dc magnetic field applied in a direction perpendicular to the microwave propagation, the Py chiral structure loaded on the center of the CPW signal line shows Kittel-mode ferromagnetic resonance. Contrastingly, the structure on the signal-line edge highlights two additional resonances: spin-wave resonance at a higher frequency, and unique resonance at a lower frequency of approximately 7.8 GHz. The resonance signal at 7.8 GHz originates from magnetically induced, geometry-driven resonance, although the resonance frequency does not depend on the external magnetic field. Moreover, the displacement of the Py structures on the signal line results in nonreciprocal microwave transmission, which is traced back to the edge-guide mode.

Finite Gyroradius Effects in the Electron Outflow of Asymmetric Magnetic Reconnection

NASA Technical Reports Server (NTRS)

Norgren, C.; Graham, D. B.; Khotyaintsev, Yu. V.; Andre, M.; Vaivads, A.; Chen, Li-Jen; Lindqvist, P.-A.; Marklund, G. T.; Ergun, R. E.; Magnes, W.;

Ionization chamber correction factors for MR-linacs

NASA Astrophysics Data System (ADS)

Pojtinger, Stefan; Steffen Dohm, Oliver; Kapsch, Ralf-Peter; Thorwarth, Daniela

2018-06-01

Previously, readings of air-filled ionization chambers have been described as being influenced by magnetic fields. To use these chambers for dosimetry in magnetic resonance guided radiotherapy (MRgRT), this effect must be taken into account by introducing a correction factor k B. The purpose of this study is to systematically investigate k B for a typical reference setup for commercially available ionization chambers with different magnetic field strengths. The Monte Carlo simulation tool EGSnrc was used to simulate eight commercially available ionization chambers in magnetic fields whose magnetic flux density was in the range of 0–2.5 T. To validate the simulation, the influence of the magnetic field was experimentally determined for a PTW30013 Farmer-type chamber for magnetic flux densities between 0 and 1.425 T. Changes in the detector response of up to 8% depending on the magnetic flux density, on the chamber geometry and on the chamber orientation were obtained. In the experimental setup, a maximum deviation of less than 2% was observed when comparing measured values with simulated values. Dedicated values for two MR-linac systems (ViewRay MRIdian, ViewRay Inc, Cleveland, United States, 0.35 T/ 6 MV and Elekta Unity, Elekta AB, Stockholm, Sweden, 1.5 T/7 MV) were determined for future use in reference dosimetry. Simulated values for thimble-type chambers are in good agreement with experiments as well as with the results of previous publications. After further experimental validation, the results can be considered for definition of standard protocols for purposes of reference dosimetry in MRgRT.

Ionization chamber correction factors for MR-linacs.

PubMed

Pojtinger, Stefan; Dohm, Oliver Steffen; Kapsch, Ralf-Peter; Thorwarth, Daniela

2018-06-07

Previously, readings of air-filled ionization chambers have been described as being influenced by magnetic fields. To use these chambers for dosimetry in magnetic resonance guided radiotherapy (MRgRT), this effect must be taken into account by introducing a correction factor k B . The purpose of this study is to systematically investigate k B for a typical reference setup for commercially available ionization chambers with different magnetic field strengths. The Monte Carlo simulation tool EGSnrc was used to simulate eight commercially available ionization chambers in magnetic fields whose magnetic flux density was in the range of 0-2.5 T. To validate the simulation, the influence of the magnetic field was experimentally determined for a PTW30013 Farmer-type chamber for magnetic flux densities between 0 and 1.425 T. Changes in the detector response of up to 8% depending on the magnetic flux density, on the chamber geometry and on the chamber orientation were obtained. In the experimental setup, a maximum deviation of less than 2% was observed when comparing measured values with simulated values. Dedicated values for two MR-linac systems (ViewRay MRIdian, ViewRay Inc, Cleveland, United States, 0.35 T/ 6 MV and Elekta Unity, Elekta AB, Stockholm, Sweden, 1.5 T/7 MV) were determined for future use in reference dosimetry. Simulated values for thimble-type chambers are in good agreement with experiments as well as with the results of previous publications. After further experimental validation, the results can be considered for definition of standard protocols for purposes of reference dosimetry in MRgRT.

Magnetic Fields Versus Gravity

NASA Astrophysics Data System (ADS)

Hensley, Kerry

2018-04-01

Deep within giant molecular clouds, hidden by dense gas and dust, stars form. Unprecedented data from the Atacama Large Millimeter/submillimeter Array (ALMA) reveal the intricate magnetic structureswoven throughout one of the most massive star-forming regions in the Milky Way.How Stars Are BornThe Horsehead Nebulasdense column of gas and dust is opaque to visible light, but this infrared image reveals the young stars hidden in the dust. [NASA/ESA/Hubble Heritage Team]Simple theory dictates that when a dense clump of molecular gas becomes massive enough that its self-gravity overwhelms the thermal pressure of the cloud, the gas collapses and forms a star. In reality, however, star formation is more complicated than a simple give and take between gravity and pressure. Thedusty molecular gas in stellar nurseries is permeated with magnetic fields, which are thought to impede the inward pull of gravity and slow the rate of star formation.How can we learn about the magnetic fields of distant objects? One way is by measuring dust polarization. An elongated dust grain will tend to align itself with its short axis parallel to the direction of the magnetic field. This systematic alignment of the dust grains along the magnetic field lines polarizes the dust grains emission perpendicular to the local magnetic field. This allows us to infer the direction of the magnetic field from the direction of polarization.Magnetic field orientations for protostars e2 and e8 derived from Submillimeter Array observations (panels a through c) and ALMA observations (panels d and e). Click to enlarge. [Adapted from Koch et al. 2018]Tracing Magnetic FieldsPatrick Koch (Academia Sinica, Taiwan) and collaborators used high-sensitivity ALMA observations of dust polarization to learn more about the magnetic field morphology of Milky Way star-forming region W51. W51 is one of the largest star-forming regions in our galaxy, home to high-mass protostars e2, e8, and North.The ALMA observations reveal polarized emission toward all three sources. By extracting the magnetic field orientations from the polarization vectors, Koch and collaborators found that the molecular cloud contains an ordered magnetic field with never-before-seen structures. Several small clumps on the perimeter of the massive star-forming cores exhibit comet-shaped magnetic field structures, which could indicate that these smaller cores are being pulled toward the more massive cores.These findings hint that the magnetic field structure can tell us about the flow of material within star-forming regions key to understanding the nature of star formation itself.Maps of sin for two of the protostars (e2 and e8) and their surroundings. [Adapted from Koch et al. 2018]Guiding Star FormationDo the magnetic fields in W51 help or hinder star formation? To explore this question,Koch and collaborators introduced the quantity sin , where is the angle between the local gravity and the local magnetic field.When the angle between gravity and the magnetic field is small (sin 0), the magnetic field has little effect on the collapse of the cloud. If gravity and the magnetic field are perpendicular (sin 1), the magnetic field can slow the infall of gas and inhibit star formation.Based on this parameter, Koch and collaborators identified narrow channels where gravity acts unimpeded by the magnetic field. These magnetic channels may funnel gas toward the dense cores and aid the star-formation process.The authors observations demonstrate just one example of the broad realm ALMAs polarimetry capabilities have opened to discovery. These and future observations of dust polarization will continue to reveal more about the delicate magnetic structure within molecular clouds, furtherilluminating the role that magnetic fields play in star formation.CitationPatrick M. Koch et al 2018 ApJ 855 39. doi:10.3847/1538-4357/aaa4c1

Guide to Magnet School Development.

ERIC Educational Resources Information Center

Blank, Rolf K.; And Others

In this guide, the results and findings of a major survey of magnet schools are organized into a practical manual for school districts to use in planning, developing, and implementing new magnet programs or improving those already in existence. The guide is divided into three sections: (1) key steps in magnet program development (an outline of…

Pneumatically Operated MRI-Compatible Needle Placement Robot for Prostate Interventions

PubMed Central

Fischer, Gregory S.; Iordachita, Iulian; Csoma, Csaba; Tokuda, Junichi; Mewes, Philip W.; Tempany, Clare M.; Hata, Nobuhiko; Fichtinger, Gabor

2011-01-01

Magnetic Resonance Imaging (MRI) has potential to be a superior medical imaging modality for guiding and monitoring prostatic interventions. The strong magnetic field prevents the use of conventional mechatronics and the confined physical space makes it extremely challenging to access the patient. We have designed a robotic assistant system that overcomes these difficulties and promises safe and reliable intra-prostatic needle placement inside closed high-field MRI scanners. The robot performs needle insertion under real-time 3T MR image guidance; workspace requirements, MR compatibility, and workflow have been evaluated on phantoms. The paper explains the robot mechanism and controller design and presents results of preliminary evaluation of the system. PMID:21686038

Pneumatically Operated MRI-Compatible Needle Placement Robot for Prostate Interventions.

PubMed

Fischer, Gregory S; Iordachita, Iulian; Csoma, Csaba; Tokuda, Junichi; Mewes, Philip W; Tempany, Clare M; Hata, Nobuhiko; Fichtinger, Gabor

2008-06-13

Magnetic Resonance Imaging (MRI) has potential to be a superior medical imaging modality for guiding and monitoring prostatic interventions. The strong magnetic field prevents the use of conventional mechatronics and the confined physical space makes it extremely challenging to access the patient. We have designed a robotic assistant system that overcomes these difficulties and promises safe and reliable intra-prostatic needle placement inside closed high-field MRI scanners. The robot performs needle insertion under real-time 3T MR image guidance; workspace requirements, MR compatibility, and workflow have been evaluated on phantoms. The paper explains the robot mechanism and controller design and presents results of preliminary evaluation of the system.

The inference of vector magnetic fields from polarization measurements with limited spectral resolution

NASA Technical Reports Server (NTRS)

Lites, B. W.; Skumanich, A.

1985-01-01

A method is presented for recovery of the vector magnetic field and thermodynamic parameters from polarization measurement of photospheric line profiles measured with filtergraphs. The method includes magneto-optic effects and may be utilized on data sampled at arbitrary wavelengths within the line profile. The accuracy of this method is explored through inversion of synthetic Stokes profiles subjected to varying levels of random noise, instrumental wave-length resolution, and line profile sampling. The level of error introduced by the systematic effect of profile sampling over a finite fraction of the 5 minute oscillation cycle is also investigated. The results presented here are intended to guide instrumental design and observational procedure.

Detection of oppositely directed reconnection jets in a solar wind current sheet

NASA Astrophysics Data System (ADS)

Davis, M. S.; Phan, T. D.; Gosling, J. T.; Skoug, R. M.

2006-10-01

We report the first two-spacecraft (Wind and ACE) detection of oppositely directed plasma jets within a bifurcated current sheet in the solar wind. The event occurred on January 3, 2003 and provides further direct evidence that such jets result from reconnection. The magnetic shear across the bifurcated current sheet at both Wind and ACE was ~150°, indicating that the magnetic shear must have been the same at the reconnection site located between the two spacecraft. These observations thus provide strong evidence for component merging with a guide field ~ 30% of the antiparallel field. The dimensionless reconnection rate based on the measured inflow was 0.03, implying fast reconnection.

Detection of oppositely directed reconnection jets in a solar wind current sheet

NASA Astrophysics Data System (ADS)

Davis, M. S.; Phan, T. D.; Gosling, J. T.; Skoug, R. M.

2006-12-01

We report the first two-spacecraft (Wind and ACE) detection of oppositely directed plasma jets within a bifurcated current sheet in the solar wind. The event occurred on January 3, 2003 and provides further direct evidence that such jets result from reconnection. The magnetic shear across the bifurcated current sheet at both Wind and ACE was approximately 150 degrees, indicating that the magnetic shear must have been the same at the reconnection site located between the two spacecraft. These observations thus provide strong evidence for component merging with a guide field approximately 30% of the antiparallel field. The dimensionless reconnection rate based on the measured inflow was 0.03, implying fast reconnection.

High-harmonic fast-wave power flow along magnetic field lines in the scrape-off layer of NSTX.

PubMed

Perkins, R J; Hosea, J C; Kramer, G J; Ahn, J-W; Bell, R E; Diallo, A; Gerhardt, S; Gray, T K; Green, D L; Jaeger, E F; Jaworski, M A; LeBlanc, B P; McLean, A; Maingi, R; Phillips, C K; Roquemore, L; Ryan, P M; Sabbagh, S; Taylor, G; Wilson, J R

2012-07-27

A significant fraction of high-harmonic fast-wave (HHFW) power applied to NSTX can be lost to the scrape-off layer (SOL) and deposited in bright and hot spirals on the divertor rather than in the core plasma. We show that the HHFW power flows to these spirals along magnetic field lines passing through the SOL in front of the antenna, implying that the HHFW power couples across the entire width of the SOL rather than mostly at the antenna face. This result will help guide future efforts to understand and minimize these edge losses in order to maximize fast-wave heating and current drive.

3D electrostatic gyrokinetic electron and fully kinetic ion simulation of lower-hybrid drift instability of Harris current sheet

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Zhenyu; Lin, Yu; Wang, Xueyi

The eigenmode stability properties of three-dimensional lower-hybrid-drift-instabilities (LHDI) in a Harris current sheet with a small but finite guide magnetic field have been systematically studied by employing the gyrokinetic electron and fully kinetic ion (GeFi) particle-in-cell (PIC) simulation model with a realistic ion-to-electron mass ratio m i/m e. In contrast to the fully kinetic PIC simulation scheme, the fast electron cyclotron motion and plasma oscillations are systematically removed in the GeFi model, and hence one can employ the realistic m i/m e. The GeFi simulations are benchmarked against and show excellent agreement with both the fully kinetic PIC simulation and the analytical eigenmode theory. Our studies indicate that, for small wavenumbers, ky, along the current direction, the most unstable eigenmodes are peaked at the location wheremore » $$\\vec{k}$$• $$\\vec{B}$$ =0, consistent with previous analytical and simulation studies. Here, $$\\vec{B}$$ is the equilibrium magnetic field and $$\\vec{k}$$ is the wavevector perpendicular to the nonuniformity direction. As ky increases, however, the most unstable eigenmodes are found to be peaked at $$\\vec{k}$$ •$$\\vec{B}$$ ≠0. Additionally, the simulation results indicate that varying m i/m e, the current sheet width, and the guide magnetic field can affect the stability of LHDI. Simulations with the varying mass ratio confirm the lower hybrid frequency and wave number scalings.« less

3D electrostatic gyrokinetic electron and fully kinetic ion simulation of lower-hybrid drift instability of Harris current sheet

DOE PAGES

Wang, Zhenyu; Lin, Yu; Wang, Xueyi; ...

2016-07-07

The eigenmode stability properties of three-dimensional lower-hybrid-drift-instabilities (LHDI) in a Harris current sheet with a small but finite guide magnetic field have been systematically studied by employing the gyrokinetic electron and fully kinetic ion (GeFi) particle-in-cell (PIC) simulation model with a realistic ion-to-electron mass ratio m i/m e. In contrast to the fully kinetic PIC simulation scheme, the fast electron cyclotron motion and plasma oscillations are systematically removed in the GeFi model, and hence one can employ the realistic m i/m e. The GeFi simulations are benchmarked against and show excellent agreement with both the fully kinetic PIC simulation and the analytical eigenmode theory. Our studies indicate that, for small wavenumbers, ky, along the current direction, the most unstable eigenmodes are peaked at the location wheremore » $$\\vec{k}$$• $$\\vec{B}$$ =0, consistent with previous analytical and simulation studies. Here, $$\\vec{B}$$ is the equilibrium magnetic field and $$\\vec{k}$$ is the wavevector perpendicular to the nonuniformity direction. As ky increases, however, the most unstable eigenmodes are found to be peaked at $$\\vec{k}$$ •$$\\vec{B}$$ ≠0. Additionally, the simulation results indicate that varying m i/m e, the current sheet width, and the guide magnetic field can affect the stability of LHDI. Simulations with the varying mass ratio confirm the lower hybrid frequency and wave number scalings.« less

Explosive X-point collapse in relativistic magnetically dominated plasma

NASA Astrophysics Data System (ADS)

Lyutikov, Maxim; Sironi, Lorenzo; Komissarov, Serguei S.; Porth, Oliver

2017-12-01

The extreme properties of the gamma-ray flares in the Crab nebula present a clear challenge to our ideas on the nature of particle acceleration in relativistic astrophysical plasma. It seems highly unlikely that standard mechanisms of stochastic type are at work here and hence the attention of theorists has switched to linear acceleration in magnetic reconnection events. In this series of papers, we attempt to develop a theory of explosive magnetic reconnection in highly magnetized relativistic plasma which can explain the extreme parameters of the Crab flares. In the first paper, we focus on the properties of the X-point collapse. Using analytical and numerical methods (fluid and particle-in-cell simulations) we extend Syrovatsky's classical model of such collapse to the relativistic regime. We find that the collapse can lead to the reconnection rate approaching the speed of light on macroscopic scales. During the collapse, the plasma particles are accelerated by charge-starved electric fields, which can reach (and even exceed) values of the local magnetic field. The explosive stage of reconnection produces non-thermal power-law tails with slopes that depend on the average magnetization . For sufficiently high magnetizations and vanishing guide field, the non-thermal particle spectrum consists of two components: a low-energy population with soft spectrum that dominates the number census; and a high-energy population with hard spectrum that possesses all the properties needed to explain the Crab flares.

Magnetism in Medicine

NASA Astrophysics Data System (ADS)

Schenck, John

2000-03-01

For centuries physicians, scientists and others have postulated an important role, either as a cause of disease or as a mode of therapy, for magnetism in medicine. Although there is a straightforward role in the removal of magnetic foreign bodies, the majority of the proposed magnetic applications have been controversial and have often been attributed by mainstream practitioners to fraud, quackery or self-deception. Calculations indicate that many of the proposed methods of action, e.g., the field-induced alignment of water molecules or alterations in blood flow, are of negligible magnitude. Nonetheless, even at the present time, the use of small surface magnets (magnetotherapy) to treat arthritis and similar diseases is a widespread form of folk medicine and is said to involve sales of approximately one billion dollars per year. Another medical application of magnetism associated with Mesmer and others (eventually known as animal magnetism) has been discredited, but has had a culturally significant role in the development of hypnotism and as one of the sources of modern psychotherapy. Over the last two decades, in marked contrast to previous applications of magnetism to medicine, magnetic resonance imaging or MRI, has become firmly established as a clinical diagnostic tool. MRI permits the non-invasive study of subtle biological processes in intact, living organisms and approximately 150,000,000 diagnostic studies have been performed since its clinical introduction in the early 1980s. The dramatically swift and widespread acceptance of MRI was made possible by scientific and engineering advances - including nuclear magnetic resonance, computer technology and whole-body-sized, high field superconducting magnets - in the decades following World War Two. Although presently used much less than MRI, additional applications, including nerve and muscle stimulation by pulsed magnetic fields, the use of magnetic forces to guide surgical instruments, and imaging utilizing the weak magnetic fields generated by brain and cardiac activity, are currently under investigation.

A Longitudinal Mode Electromagnetic Acoustic Transducer (EMAT) Based on a Permanent Magnet Chain for Pipe Inspection

PubMed Central

Cong, Ming; Wu, Xinjun; Qian, Chunqiao

2016-01-01

A new electromagnetic acoustic transducer (EMAT) design, employing a special structure of the permanent magnet chain, is proposed to generate and receive longitudinal guided waves for pipe inspection based on the magnetostriction mechanism. Firstly, a quantitative analysis of the excitation forces shows the influence of the radial component can be ignored. Furthermore, as the axial component of the static magnetic field is dominant, a method of solenoid testing coils connected in series is adopted to increase the signal amplitude. Then, two EMAT configurations are developed to generate and receive the L(0,2) guided wave mode. The experimental results show the circumferential notch can be identified and located successfully. Finally, a detailed investigation of the performance of the proposed EMATs is given. Compared to the conventional EMAT configuration, the proposed configurations have the advantages of small volume, light weight, easy installation and portability, which is helpful to improve inspection efficiency. PMID:27213400

Simultaneous acquisition of magnetic resonance spectroscopy (MRS) data and positron emission tomography (PET) images with a prototype MR-compatible, small animal PET imager

NASA Astrophysics Data System (ADS)

Raylman, Raymond R.; Majewski, Stan; Velan, S. Sendhil; Lemieux, Susan; Kross, Brian; Popov, Vladimir; Smith, Mark F.; Weisenberger, Andrew G.

2007-06-01

Multi-modality imaging (such as PET-CT) is rapidly becoming a valuable tool in the diagnosis of disease and in the development of new drugs. Functional images produced with PET, fused with anatomical images created by MRI, allow the correlation of form with function. Perhaps more exciting than the combination of anatomical MRI with PET, is the melding of PET with MR spectroscopy (MRS). Thus, two aspects of physiology could be combined in novel ways to produce new insights into the physiology of normal and pathological processes. Our team is developing a system to acquire MRI images and MRS spectra, and PET images contemporaneously. The prototype MR-compatible PET system consists of two opposed detector heads (appropriate in size for small animal imaging), operating in coincidence mode with an active field-of-view of ˜14 cm in diameter. Each detector consists of an array of LSO detector elements coupled through a 2-m long fiber optic light guide to a single position-sensitive photomultiplier tube. The use of light guides allows these magnetic field-sensitive elements of the PET imager to be positioned outside the strong magnetic field of our 3T MRI scanner. The PET scanner imager was integrated with a 12-cm diameter, 12-leg custom, birdcage coil. Simultaneous MRS spectra and PET images were successfully acquired from a multi-modality phantom consisting of a sphere filled with 17 brain relevant substances and a positron-emitting radionuclide. There were no significant changes in MRI or PET scanner performance when both were present in the MRI magnet bore. This successful initial test demonstrates the potential for using such a multi-modality to obtain complementary MRS and PET data.

Dependence of sodium laser guide star photon return on the geomagnetic field

NASA Astrophysics Data System (ADS)

Moussaoui, N.; Holzlöhner, R.; Hackenberg, W.; Bonaccini Calia, D.

2009-07-01

Aims: The efficiency of optical pumping that increases the backscatter emission of mesospheric sodium atoms in continuous wave (cw) laser guide stars (LGSs) can be significantly reduced and, in the worst case, eliminated by the action of the geomagnetic field. Our goal is to present an estimation of this effect for several telescope sites. Methods: Sodium atoms precess around magnetic field lines that cycle the magnetic quantum number, reducing the effectiveness of optical pumping. Our method is based on calculating the sodium magnetic sublevel populations in the presence of the geomagnetic field and on experimental measurements of radiance return from sodium LGS conducted at the Starfire optical range (SOR). Results: We propose a relatively simple semi-empirical formula for estimating the effect of the geomagnetic field on enhancing the LGSs photon return due to optical pumping with a circularly polarized cw single-frequency laser beam. Starting from the good agreement between our calculations and the experimental measurements for the geomagnetic field effect, and in order to more realistically estimate the sodium LGSs photon return, we introduce the effect of the distance to the mesospheric sodium layer and the atmospheric attenuation. The combined effect of these three factors is calculated for several telescope sites. Conclusions: In calculating the return flux of LGSs, only the best return conditions are often assumed, relying on strong optical pumping with circularly polarized lasers. However, one can only obtain this optimal return along one specific laser orientation on the sky, where the geomagnetic field lines are parallel to the laser beam. For most of the telescopes, the optimum can be obtained at telescope orientations beyond the observation limit. For the telescopes located close to the geomagnetic pole, the benefit of the optical pumping is much more important than for telescopes located close to the geomagnetic equator.

High-resolution small field-of-view magnetic resonance image acquisition system using a small planar coil and a pneumatic manipulator in an open MRI scanner.

PubMed

Miki, Kohei; Masamune, Ken

2015-10-01

Low-field open magnetic resonance imaging (MRI) is frequently used for performing image-guided neurosurgical procedures. Intraoperative magnetic resonance (MR) images are useful for tracking brain shifts and verifying residual tumors. However, it is difficult to precisely determine the boundary of the brain tumors and normal brain tissues because the MR image resolution is low, especially when using a low-field open MRI scanner. To overcome this problem, a high-resolution MR image acquisition system was developed and tested. An MR-compatible manipulator with pneumatic actuators containing an MR signal receiver with a small radiofrequency (RF) coil was developed. The manipulator had five degrees of freedom for position and orientation control of the RF coil. An 8-mm planar RF coil with resistance and inductance of 2.04 [Formula: see text] and 1.00 [Formula: see text] was attached to the MR signal receiver at the distal end of the probe. MR images of phantom test devices were acquired using the MR signal receiver and normal head coil for signal-to-noise ratio (SNR) testing. The SNR of MR images acquired using the MR signal receiver was 8.0 times greater than that of MR images acquired using the normal head coil. The RF coil was moved by the manipulator, and local MR images of a phantom with a 2-mm grid were acquired using the MR signal receiver. A wide field-of-view MR image was generated from a montage of local MR images. A small field-of-view RF system with a pneumatic manipulator was integrated in a low-field MRI scanner to allow acquisition of both wide field-of-view and high-resolution MR images. This system is promising for image-guided neurosurgery as it may allow brain tumors to be observed more clearly and removed precisely.

Prospective evaluation of magnetic resonance imaging guided in-bore prostate biopsy versus systematic transrectal ultrasound guided prostate biopsy in biopsy naïve men with elevated prostate specific antigen.

PubMed

Quentin, Michael; Blondin, Dirk; Arsov, Christian; Schimmöller, Lars; Hiester, Andreas; Godehardt, Erhard; Albers, Peter; Antoch, Gerald; Rabenalt, Robert

2014-11-01

Magnetic resonance imaging guided biopsy is increasingly performed to diagnose prostate cancer. However, there is a lack of well controlled, prospective trials to support this treatment method. We prospectively compared magnetic resonance imaging guided in-bore biopsy with standard systematic transrectal ultrasound guided biopsy in biopsy naïve men with increased prostate specific antigen. We performed a prospective study in 132 biopsy naïve men with increased prostate specific antigen (greater than 4 ng/ml). After 3 Tesla functional multiparametric magnetic resonance imaging patients were referred for magnetic resonance imaging guided in-bore biopsy of prostate lesions (maximum 3) followed by standard systematic transrectal ultrasound guided biopsy (12 cores). We analyzed the detection rates of prostate cancer and significant prostate cancer (greater than 5 mm total cancer length or any Gleason pattern greater than 3). A total of 128 patients with a mean ± SD age of 66.1 ± 8.1 years met all study requirements. Median prostate specific antigen was 6.7 ng/ml (IQR 5.1-9.0). Transrectal ultrasound and magnetic resonance imaging guided biopsies provided the same 53.1% detection rate, including 79.4% and 85.3%, respectively, for significant prostate cancer. Magnetic resonance imaging and transrectal ultrasound guided biopsies missed 7.8% and 9.4% of clinically significant prostate cancers, respectively. Magnetic resonance imaging biopsy required significantly fewer cores and revealed a higher percent of cancer involvement per biopsy core (each p <0.01). Combining the 2 methods provided a 60.9% detection rate with an 82.1% rate for significant prostate cancer. Magnetic resonance imaging guided in-bore and systematic transrectal ultrasound guided biopsies achieved equally high detection rates in biopsy naïve patients with increased prostate specific antigen. Magnetic resonance imaging guided in-bore biopsies required significantly fewer cores and revealed a significantly higher percent of cancer involvement per biopsy core. Copyright © 2014 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Construction of a 1 MeV Electron Accelerator for High Precision Beta Decay Studies

NASA Astrophysics Data System (ADS)

Longfellow, Brenden

2014-09-01

Beta decay energy calibration for detectors is typically established using conversion sources. However, the calibration points from conversion sources are not evenly distributed over the beta energy spectrum and the foil backing of the conversion sources produces perturbations in the calibration spectrum. To improve this, an external, tunable electron beam coupled by a magnetic field can be used to calibrate the detector. The 1 MeV electron accelerator in development at Triangle Universities Nuclear Laboratory (TUNL) utilizes a pelletron charging system. The electron gun shoots 104 electrons per second with an energy range of 50 keV to 1 MeV and is pulsed at a 10 kHz rate with a few ns width. The magnetic field in the spectrometer is 1 T and guiding fields of 0.01 to 0.05 T for the electron gun are used to produce a range of pitch angles. This accelerator can be used to calibrate detectors evenly over its energy range and determine the detector response over a range of pitch angles. Beta decay energy calibration for detectors is typically established using conversion sources. However, the calibration points from conversion sources are not evenly distributed over the beta energy spectrum and the foil backing of the conversion sources produces perturbations in the calibration spectrum. To improve this, an external, tunable electron beam coupled by a magnetic field can be used to calibrate the detector. The 1 MeV electron accelerator in development at Triangle Universities Nuclear Laboratory (TUNL) utilizes a pelletron charging system. The electron gun shoots 104 electrons per second with an energy range of 50 keV to 1 MeV and is pulsed at a 10 kHz rate with a few ns width. The magnetic field in the spectrometer is 1 T and guiding fields of 0.01 to 0.05 T for the electron gun are used to produce a range of pitch angles. This accelerator can be used to calibrate detectors evenly over its energy range and determine the detector response over a range of pitch angles. TUNL REU Program.

Three dimensional fluid-kinetic model of a magnetically guided plasma jet

NASA Astrophysics Data System (ADS)

Ramos, Jesús J.; Merino, Mario; Ahedo, Eduardo

2018-06-01

A fluid-kinetic model of the collisionless plasma flow in a convergent-divergent magnetic nozzle is presented. The model combines the leading-order Vlasov equation and the fluid continuity and perpendicular momentum equation for magnetized electrons, and the fluid equations for cold ions, which must be solved iteratively to determine the self-consistent plasma response in a three-dimensional magnetic field. The kinetic electron solution identifies three electron populations and provides the plasma density and pressure tensor. The far downstream asymptotic behavior shows the anisotropic cooling of the electron populations. The fluid equations determine the electric potential and the fluid velocities. In the small ion-sound gyroradius case, the solution is constructed one magnetic line at a time. In the large ion-sound gyroradius case, ion detachment from magnetic lines makes the problem fully three-dimensional.

ELECTRON ACCELERATION IN CONTRACTING MAGNETIC ISLANDS DURING SOLAR FLARES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borovikov, D.; Tenishev, V.; Gombosi, T. I.

Electron acceleration in solar flares is well known to be efficient at generating energetic particles that produce the observed bremsstrahlung X-ray spectra. One mechanism proposed to explain the observations is electron acceleration within contracting magnetic islands formed by magnetic reconnection in the flare current sheet. In a previous study, a numerical magnetohydrodynamic simulation of an eruptive solar flare was analyzed to estimate the associated electron acceleration due to island contraction. That analysis used a simple analytical model for the island structure and assumed conservation of the adiabatic invariants of particle motion. In this paper, we perform the first-ever rigorous integrationmore » of the guiding-center orbits of electrons in a modeled flare. An initially isotropic distribution of particles is seeded in a contracting island from the simulated eruption, and the subsequent evolution of these particles is followed using guiding-center theory. We find that the distribution function becomes increasingly anisotropic over time as the electrons’ energy increases by up to a factor of five, in general agreement with the previous study. In addition, we show that the energized particles are concentrated on the Sunward side of the island, adjacent to the reconnection X-point in the flare current sheet. Furthermore, our analysis demonstrates that the electron energy gain is dominated by betatron acceleration in the compressed, strengthened magnetic field of the contracting island. Fermi acceleration by the shortened field lines of the island also contributes to the energy gain, but it is less effective than the betatron process.« less

Violation of Field Line Conservation and Associated Spatial Scales in Particle-in-Cell Simulations and MMS Data

NASA Astrophysics Data System (ADS)

Wendel, D. E.; Liu, Y. H.; Giles, B. L.; Torbert, R. B.

2017-12-01

For the first time, space flight technology exists to detect, in situ, violation of magnetic field line conservation. The violation of magnetic line conservation on scales smaller than the system size is a necessary and sufficient condition for magnetic reconnection. We demonstrate that violation of line conservation produces a detectable, structured signature in both particle-in-cell simulations of reconnection and in data from the Magnetospheric Multi-Scale mission. In particle-in-cell simulations of asymmetric reconnection, the quantity-which we call M-that identifies this violation achieves a significant value in electron skin depth-scale layers that extend from the electron diffusion region along the separatrices, with higher values emerging on the low density, high magnetic field side of the current sheet. In two MMS burst data intervals associated with detection of the electron diffusion region—one interval with antiparallel reconnecting fields and the other with a guide field-we determine the location and scale of M and of the diffusion region relative to electron outflows and the magnetic separatrices. We find that M exceeds measurement uncertainties both at the diffusion region and near the separatrices, where it attains its highest values in layered structures. The observed magnitude scales as the simulated magnitude after adjusting for the artificial parameters of the simulation. Bipolar forms of the quantity also appear further from the diffusion region, possibly associated with electron holes. The measure serves not only as a powerful diagnostic for magnetic reconnection, but reveals that electrons transport this signature of reconnection away from the x-line.

Dynamics of paramagnetic agents by off-resonance rotating frame technique

NASA Astrophysics Data System (ADS)

Zhang, Huiming; Xie, Yang

2006-12-01

Off-resonance rotating frame technique offers a novel tool to explore the dynamics of paramagnetic agents at high magnetic fields ( B0 > 3 T). Based on the effect of paramagnetic relaxation enhancement in the off-resonance rotating frame, a new method is described here for determining the dynamics of paramagnetic ion chelates from the residual z-magnetizations of water protons. In this method, the dynamics of the chelates are identified by the difference magnetization profiles, which are the subtraction of the residual z-magnetization as a function of frequency offset obtained at two sets of RF amplitude ω1 and pulse duration τ. The choices of ω1 and τ are guided by a 2-D magnetization map that is created numerically by plotting the residual z-magnetization as a function of effective field angle θ and off-resonance pulse duration τ. From the region of magnetization map that is the most sensitive to the alteration of the paramagnetic relaxation enhancement efficiency R1 ρ/ R1, the ratio of the off-resonance rotating frame relaxation rate constant R1 ρ verse the laboratory frame relaxation rate constant R1, three types of difference magnetization profiles can be generated. The magnetization map and the difference magnetization profiles are correlated with the rotational correlation time τR of Gd-DTPA through numerical simulations, and further validated by the experimental data for a series of macromolecule conjugated Gd-DTPA in aqueous solutions. Effects of hydration water number q, diffusion coefficient D, magnetic field strength B0 and multiple rotational correlation times are explored with the simulations of the magnetization map. This method not only provides a simple and reliable approach to determine the dynamics of paramagnetic labeling of molecular/cellular events at high magnetic fields, but also a new strategy for spectral editing in NMR/MRI based on the dynamics of paramagnetic labeling in vivo.

Observational Signatures of Magnetic Reconnection

NASA Technical Reports Server (NTRS)

Savage, Sabrina

2014-01-01

Magnetic reconnection is often referred to as the primary source of energy release during solar flares. Directly observing reconnection occurring in the solar atmosphere, however, is not trivial considering that the scale size of the diffusion region is magnitudes smaller than the observational capabilities of current instrumentation, and coronal magnetic field measurements are not currently sufficient to capture the process. Therefore, predicting and studying observationally feasible signatures of the precursors and consequences of reconnection is necessary for guiding and verifying the simulations that dominate our understanding. I will present a set of such observations, particularly in connection with long-duration solar events, and compare them with recent simulations and theoretical predictions.

Intraoperative MR-guided DBS implantation for treating PD and ET

NASA Astrophysics Data System (ADS)

Liu, Haiying; Maxwell, Robert E.; Truwit, Charles L.

2001-05-01

Deep brain stimulator (DBS) implantation is a promising treatment alternative for suppressing the motor tremor symptoms in Parkinson disease (PD) patient. The main objective is to develop a minimally invasive approach using high spatial resolution and soft-tissue contrast MR imaging techniques to guide the surgical placement of DBS. In the MR-guided procedure, the high spatial resolution MR images were obtained intra-operatively and used to target stereotactically a specific deep brain location. The neurosurgery for craniotomy was performed in the front of the magnet outside of the 10 Gauss line. Aided with positional registration assembly for the stereotactic head frame, the target location (VIM or GPi or STN) in deep brain areas was identified and measured from the MR images in reference to the markers in the calibration assembly of the head frame before the burrhole prep. In 20 patients, MR- guided DBS implantations have been performed according to the new methodology. MR-guided DBS implantation at high magnetic field strength has been shown to be feasible and desirable. In addition to the improved outcome, this offers a new surgical approach in which intra-operative visualization is possible during intervention, and any complications such as bleeding can be assessed in situ immediately prior to dural closure.

Safety of High Speed Guided Ground Transportation Systems - Magnetic and Electric Field Testing of the Massachusetts Bay Transportation Authority (MBTA) Urban Transit System: Volume I - Analysis

DOT National Transportation Integrated Search

1993-06-01

The safety of magnetlcally levitated (maglev) and high speed rail (HSR) trains proposed for application in the : United States is the responsibility of the Federal Railroad Administratlon (FRA). Plans for near future US applications : include maglev ...

An Elementary Model of the Earth's Magnetic Field

ERIC Educational Resources Information Center

Watt, Jeanie I.; Roth, Bradley J.

2007-01-01

This article is intended as a guide for teaching geomagnetism in a high school or university introductory physics class. Many students find this subject fascinating. Instructors, however, often have a difficult time introducing this topic at an elementary level. Suggestions will be made on how to accomplish this using three electricity and…

Safety of High Speed Guided Ground Transportation Systems: Potential Health Effects of Low Frequency Electromagnetic Fields Due to Maglev and Other Electric Rail Systems

DOT National Transportation Integrated Search

1993-08-01

The safety of magnetically-levitated (maglev) and high-speed rail (HSR) trains proposed for use in the United States is : the responsibility of the Federal Railroad Administration. There are concerns for physical safety associated with : equipment op...

Electron acceleration in the Solar corona - 3D PiC code simulations of guide field reconnection

NASA Astrophysics Data System (ADS)

Alejandro Munoz Sepulveda, Patricio

2017-04-01

The efficient electron acceleration in the solar corona detected by means of hard X-ray emission is still not well understood. Magnetic reconnection through current sheets is one of the proposed production mechanisms of non-thermal electrons in solar flares. Previous works in this direction were based mostly on test particle calculations or 2D fully-kinetic PiC simulations. We have now studied the consequences of self-generated current-aligned instabilities on the electron acceleration mechanisms by 3D magnetic reconnection. For this sake, we carried out 3D Particle-in-Cell (PiC) code numerical simulations of force free reconnecting current sheets, appropriate for the description of the solar coronal plasmas. We find an efficient electron energization, evidenced by the formation of a non-thermal power-law tail with a hard spectral index smaller than -2 in the electron energy distribution function. We discuss and compare the influence of the parallel electric field versus the curvature and gradient drifts in the guiding-center approximation on the overall acceleration, and their dependence on different plasma parameters.

Modification of the parallel scattering mean free path of cosmic rays in the presence of adiabatic focusing

DOE Office of Scientific and Technical Information (OSTI.GOV)

He, H.-Q.; Schlickeiser, R., E-mail: hqhe@mail.iggcas.ac.cn, E-mail: rsch@tp4.rub.de

The cosmic ray mean free path in a large-scale nonuniform guide magnetic field with superposed magnetostatic turbulence is calculated to clarify some conflicting results in the literature. A new, exact integro-differential equation for the cosmic-ray anisotropy is derived from the Fokker-Planck transport equation. A perturbation analysis of this integro-differential equation leads to an analytical expression for the cosmic ray anisotropy and the focused transport equation for the isotropic part of the cosmic ray distribution function. The derived parallel spatial diffusion coefficient and the associated cosmic ray mean free path include the effect of adiabatic focusing and reduce to the standardmore » forms in the limit of a uniform guide magnetic field. For the illustrative case of isotropic pitch angle scattering, the derived mean free path agrees with the earlier expressions of Beeck and Wibberenz, Bieber and Burger, Kota, and Litvinenko, but disagrees with the result of Shalchi. The disagreement with the expression of Shalchi is particularly strong in the limit of strong adiabatic focusing.« less

Preliminary experimental investigation of a Ku-band radial line oscillator based on transition radiation effect

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dang, Fangchao, E-mail: dangfangchao@sina.com; Zhang, Xiaoping; Zhong, Huihuang

2015-09-15

A Ku-band radial line oscillator (RLO) with low guiding magnetic field was proposed in our previous work. In order to weaken the impedance mismatch between the oscillator and an intense electron accelerator with higher impedance, a transverse electromagnetic reflector is added to improve the RLO, which is favorable to increase the Q-factor and accelerate the device saturation. A preliminary experiment is carried out to investigate the performance of the improved RLO. The radial-radiated electron beam is restrained well under the designed guiding magnetic field of 0.52 T. The preliminary experimental results indicates that high power microwaves with a power of 120 MWmore » and a frequency of 14.12 GHz are generated when the diode voltage is 420 kV and the beam current 14.2 kA. The experimental results suggest the feasibility of the presented RLO generating high power microwaves at a high frequency band. Additionally, more work is needed regarding promotion of the electron beam quality and the impedance match between the electron beam accelerator and the oscillator.« less

Efficient magneto-optical mode converter on glass

NASA Astrophysics Data System (ADS)

Garayt, Jean Philippe; Parsy, François; Jamon, Damien; Neveu, Sophie; Royer, François; Ghibaudo, Elise; Broquin, Jean-Emmanuel

2014-03-01

The integration of magneto-optical materials to realize non-reciprocal functions is still a difficult problem, because classical magneto-optical materials require an annealing temperature as high as 700°C. In this framework, this study shows how it is possible to realize efficient magneto-optical mode converter using the association of a magnetic nanoparticles silica/zirconia composite with an ion-exchanged glass waveguide. Using a sol gel process, a silica/zirconia matrix is doped by magnetic nanoparticles (CoFe2O4) and coated on a glass substrate containing straight channel waveguides made by a silver/sodium ion exchange. The extremities of the guides were previously buried using electric field-assisted burial in order to facilitate light injection. Soft annealing (90°C) and UV treatment, both compatible with the ion exchange process, have been implemented to finalize the magneto-optical film. Depending on the amount of nanoparticles in the composite, on the spatial distribution of the field in the guide and on the modal birefringence of the hybrid structure, the TE-TM conversion varies from several degrees to several tens of degrees.

In Situ Tissue Engineering Using Magnetically Guided Three-Dimensional Cell Patterning

PubMed Central

Grogan, Shawn P.; Pauli, Chantal; Chen, Peter; Du, Jiang; Chung, Christine B.; Kong, Seong Deok; Colwell, Clifford W.; Lotz, Martin K.; Jin, Sungho

2012-01-01

Manipulation of cell patterns in three dimensions in a manner that mimics natural tissue organization and function is critical for cell biological studies and likely essential for successfully regenerating tissues—especially cells with high physiological demands, such as those of the heart, liver, lungs, and articular cartilage.1,2 In the present study, we report on the feasibility of arranging iron oxide-labeled cells in three-dimensional hydrogels using magnetic fields. By manipulating the strength, shape, and orientation of the magnetic field and using crosslinking gradients in hydrogels, multi-directional cell arrangements can be produced in vitro and even directly in situ. We show that these ferromagnetic particles are nontoxic between 0.1 and 10 mg/mL; certain species of particles can permit or even enhance tissue formation, and these particles can be tracked using magnetic resonance imaging. Taken together, this approach can be adapted for studying basic biological processes in vitro, for general tissue engineering approaches, and for producing organized repair tissues directly in situ. PMID:22224660

Remote magnetic navigation for accurate, real-time catheter positioning and ablation in cardiac electrophysiology procedures.

PubMed

Filgueiras-Rama, David; Estrada, Alejandro; Shachar, Josh; Castrejón, Sergio; Doiny, David; Ortega, Marta; Gang, Eli; Merino, José L

2013-04-21

New remote navigation systems have been developed to improve current limitations of conventional manually guided catheter ablation in complex cardiac substrates such as left atrial flutter. This protocol describes all the clinical and invasive interventional steps performed during a human electrophysiological study and ablation to assess the accuracy, safety and real-time navigation of the Catheter Guidance, Control and Imaging (CGCI) system. Patients who underwent ablation of a right or left atrium flutter substrate were included. Specifically, data from three left atrial flutter and two counterclockwise right atrial flutter procedures are shown in this report. One representative left atrial flutter procedure is shown in the movie. This system is based on eight coil-core electromagnets, which generate a dynamic magnetic field focused on the heart. Remote navigation by rapid changes (msec) in the magnetic field magnitude and a very flexible magnetized catheter allow real-time closed-loop integration and accurate, stable positioning and ablation of the arrhythmogenic substrate.

Remote Magnetic Navigation for Accurate, Real-time Catheter Positioning and Ablation in Cardiac Electrophysiology Procedures

PubMed Central

Filgueiras-Rama, David; Estrada, Alejandro; Shachar, Josh; Castrejón, Sergio; Doiny, David; Ortega, Marta; Gang, Eli; Merino, José L.

2013-01-01

New remote navigation systems have been developed to improve current limitations of conventional manually guided catheter ablation in complex cardiac substrates such as left atrial flutter. This protocol describes all the clinical and invasive interventional steps performed during a human electrophysiological study and ablation to assess the accuracy, safety and real-time navigation of the Catheter Guidance, Control and Imaging (CGCI) system. Patients who underwent ablation of a right or left atrium flutter substrate were included. Specifically, data from three left atrial flutter and two counterclockwise right atrial flutter procedures are shown in this report. One representative left atrial flutter procedure is shown in the movie. This system is based on eight coil-core electromagnets, which generate a dynamic magnetic field focused on the heart. Remote navigation by rapid changes (msec) in the magnetic field magnitude and a very flexible magnetized catheter allow real-time closed-loop integration and accurate, stable positioning and ablation of the arrhythmogenic substrate. PMID:23628883

Magnetofection™ of NMDA Receptor Subunits GluN1 and GluN2A Expression Vectors in Non-Neuronal Host Cells.

PubMed

Bruneau, Nadine; Szepetowski, Pierre

2017-01-01

The functional study of reconstituted NMDA receptors (NMDARs) in host cells requires that the corresponding vectors for the expression of the NMDAR subunits are co-transfected with high efficiency. Magnetofection™ is a technology used to deliver nucleic acids to cells. It is driven and site-specifically guided by the attractive forces of magnetic fields acting on magnetic nanoparticles that are associated with nucleic acid vectors. In magnetofection™, cationic lipids form self-assembled complexes with the nucleic acid vectors of interest. Those complexes are then associated with magnetic nanoparticles that are concentrated at the surface of cultured cells by applying a permanent magnetic field. Magnetofection™ is a simple method to transfect cultured cells with high transfection rates. Satisfactory expression levels are obtained with very low amounts of nucleic acid vector. Moreover, incubation time with host cells is less than 1 h, as compared with the several hours needed with standard transfection assays.

A variable torque motor compatible with magnetic resonance imaging

NASA Astrophysics Data System (ADS)

Roeck, W. W.; Ha, S.-H.; Farmaka, S.; Nalcioglu, O.

2009-04-01

High magnetic fields used in magnetic resonance imaging (MRI) do not allow the employment of conventional motors due to various incompatibility issues. This paper reports on a new motor that can operate in or near high field magnets used for MRI. The motor was designed to be operational with the MRI equipment and could be used in a rotating imaging gantry inside the magnet designed for dual modality imaging. Furthermore, it could also be used for image guided robotic interventional procedures inside a MRI system if so desired. The prototype motor was developed using magnetic resonance (MR) compatible materials, and its functionality with MR imaging was evaluated experimentally by measuring the performance of the motor and its effect on the MR image quality. Since in our application, namely, single photon emission tomography, the motor has to perform precise stepping of the gantry in small angular steps the most important parameter is the start-up torque. The experimental results showed that the motor has a start-up torque up to 1.37 Nm and rotates at 196 rpm when a constant voltage difference of 12 V is applied at a magnetic field strength of 1 T. The MR image quality was quantified by measuring the signal-to-noise of images acquired under different conditions. The results presented here indicate that the motor is MR compatible and could be used for rotating an imaging gantry or a surgical device inside the magnet.

Electron scale magnetic reconnection in the turbulent magnetosheath: Kinetic PIC simulation study

NASA Astrophysics Data System (ADS)

Sharma, P.; Shay, M. A.; Drake, J. F.; Phan, T.; Haggerty, C. C.; TenBarge, J. M.; Cassak, P.; Swisdak, M.

2017-12-01

Recent MMS observations have revealed electron scale reconnection in the turbulent magnetosheath. Surprisingly, although one of the reconnection events is associated with a very strong guide field, the ions show no coupling to the reconnection dynamics. We first review the MMS observations. Then, using kinetic PIC simulations with similar plasma conditions, we study reconnection at electron scales and show that the reconnection exhibits whistler-like dynamics similar to the case of anti-parallel reconnection rather than the kinetic Alfven wave dynamics that is often associated with reconnection with a strong guide field. We study the factors controlling this behavior and discuss the implications for reconnection and turbulence at electron scales in both the magnetosheath and solar wind.

MR-guided Focused Ultrasound for Uterine Fibroids

MedlinePlus

... Professions Site Index A-Z MR-guided Focused Ultrasound for Uterine Fibroids Magnetic Resonance-guided Focused Ultrasound ( ... are the limitations of MRgFUS? What is Focused Ultrasound of Uterine Fibroids? Magnetic Resonance-guided Focused Ultrasound ( ...

Magnetic properties of superparamagnetic nanoparticles loaded into silicon nanotubes.

PubMed

Granitzer, Petra; Rumpf, Klemens; Gonzalez, Roberto; Coffer, Jeffery; Reissner, Michael

2014-01-01

In this work, the magnetic properties of silicon nanotubes (SiNTs) filled with Fe3O4 nanoparticles (NPs) are investigated. SiNTs with different wall thicknesses of 10 and 70 nm and an inner diameter of approximately 50 nm are prepared and filled with superparamagnetic iron oxide nanoparticles of 4 and 10 nm in diameter. The infiltration process of the NPs into the tubes and dependence on the wall-thickness is described. Furthermore, data from magnetization measurements of the nanocomposite systems are analyzed in terms of iron oxide nanoparticle size dependence. Such biocompatible nanocomposites have potential merit in the field of magnetically guided drug delivery vehicles. 61.46.Fg; 62.23.Pq; 75.75.-c; 75.20.-g.

High field gradient particle accelerator

DOEpatents

Nation, J.A.; Greenwald, S.

1989-05-30

A high electric field gradient electron accelerator utilizing short duration, microwave radiation, and capable of operating at high field gradients for high energy physics applications or at reduced electric field gradients for high average current intermediate energy accelerator applications is disclosed. Particles are accelerated in a smooth bore, periodic undulating waveguide, wherein the period is so selected that the particles slip an integral number of cycles of the r.f. wave every period of the structure. This phase step of the particles produces substantially continuous acceleration in a traveling wave without transverse magnetic or other guide means for the particle. 10 figs.

SU-E-P-14: Dosimetric Effects of Magnetic Field in MRI-Guided Radiation Therapy Delivery for Breast Cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, G; Currey, A; Li, X

2015-06-15

Purpose: MRI-guided radiation therapy (RT) delivery would be beneficial for breast irradiation. The electron return effect due to the presence of a transverse magnetic field (TMF) may cause dosimetric issues on dose on skin and at the lung-tissue interface. The purpose of this study is to investigate these issues. Methods: IMRT plans with tangential beams and VMAT plans with 200 degree arcs to cover ipsilateral breast were generated for 10 randomly selected breast cancer cases using a research planning system (Monaco, Elekta) utilizing Monte Carlo dose calculation with or without a TMF of 1.5 T. Plans were optimized to delivermore » uniform dose to the whole breast with an exclusion of 5 mm tissue under the skin (PTV-EVAL). All four plans for each patient were re-scaled to have the same PTV-EVAL volume to receive the same prescription dose. The skin is defined as the first 5 mm of ipsilateral-breast tissue, plus extensions in the surrounding region. Results: The presence of 1.5 T TMF resulted in (1)increased skin dose, with the mean and maximum skin dose increase of 5% and 9%, respectively; (2) similar dose homogeneity within the PTV-EVAL; (3) the slightly improved (3%) dose homogeneity in the whole breast; (4) Averages of 9 and 16% increases in V5 and V20, respectively, for ipsilateral lung; and (5) increased the mean heart dose by 34%. VMAT plans don’t improve whole breast dose uniformity as compared that to the tangential plans. Conclusion: The presence of transverse magnetic field in MRI-guided RT delivery for whole breast irradiation can Result in slightly improved dose homogeneity in the whole breast, increased dose to the ipsilateral lung, heart, and skin. Plan optimization with additional specific dose volume constraints may eliminate/reduce these dose increases. This work is partially supported by Elekta Inc.« less

Flow-orthogonal bead oscillation in a microfluidic chip with a magnetic anisotropic flux-guide array.

PubMed

van Pelt, Stijn; Derks, Roy; Matteucci, Marco; Hansen, Mikkel Fougt; Dietzel, Andreas

2011-04-01

A new concept for the manipulation of superparamagnetic beads inside a microfluidic chip is presented in this paper. The concept allows for bead actuation orthogonal to the flow direction inside a microchannel. Basic manipulation functionalities were studied by means of finite element simulations and results were oval-shaped steady state oscillations with bead velocities up to 500 μm/s. The width of the trajectory could be controlled by prescribing external field rotation. Successful verification experiments were performed on a prototype chip fabricated with excimer laser ablation in polycarbonate and electroforming of nickel flux-guides. Bead velocities up to 450 μm/s were measured in a 75 μm wide channel. By prescribing the currents in the external quadrupole magnet, the shape of the bead trajectory could be controlled.

Magnetic resonance imaging in precision radiation therapy for lung cancer

PubMed Central

Bainbridge, Hannah; Salem, Ahmed; Tijssen, Rob H. N.; Dubec, Michael; Wetscherek, Andreas; Van Es, Corinne; Belderbos, Jose; Faivre-Finn, Corinne

2017-01-01

Radiotherapy remains the cornerstone of curative treatment for inoperable locally advanced lung cancer, given concomitantly with platinum-based chemotherapy. With poor overall survival, research efforts continue to explore whether integration of advanced radiation techniques will assist safe treatment intensification with the potential for improving outcomes. One advance is the integration of magnetic resonance imaging (MRI) in the treatment pathway, providing anatomical and functional information with excellent soft tissue contrast without exposure of the patient to radiation. MRI may complement or improve the diagnostic staging accuracy of F-18 fluorodeoxyglucose position emission tomography and computerized tomography imaging, particularly in assessing local tumour invasion and is also effective for identification of nodal and distant metastatic disease. Incorporating anatomical MRI sequences into lung radiotherapy treatment planning is a novel application and may improve target volume and organs at risk delineation reproducibility. Furthermore, functional MRI may facilitate dose painting for heterogeneous target volumes and prediction of normal tissue toxicity to guide adaptive strategies. MRI sequences are rapidly developing and although the issue of intra-thoracic motion has historically hindered the quality of MRI due to the effect of motion, progress is being made in this field. Four-dimensional MRI has the potential to complement or supersede 4D CT and 4D F-18-FDG PET, by providing superior spatial resolution. A number of MR-guided radiotherapy delivery units are now available, combining a radiotherapy delivery machine (linear accelerator or cobalt-60 unit) with MRI at varying magnetic field strengths. This novel hybrid technology is evolving with many technical challenges to overcome. It is anticipated that the clinical benefits of MR-guided radiotherapy will be derived from the ability to adapt treatment on the fly for each fraction and in real-time, using ‘beam-on’ imaging. The lung tumour site group of the Atlantic MR-Linac consortium is working to generate a challenging MR-guided adaptive workflow for multi-institution treatment intensification trials in this patient group. PMID:29218271

Safety of high speed guided ground transportation systems. Magnetic and electric field testing of the French Train a Grande Vitesse (TGV) rail systems. Volume 1. Analysis. Final report, September 1992-March 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dietrich, F.M.; Papas, P.N.; Jacobs, W.L.

The safety of magnetically levitated (maglev) and high speed rail (HSR) trains proposed for application in the United States is the responsibility of the Federal Railroad Administration (FRA). A franchise has been awarded to the Texas high Speed Rail Corporation to operate a 200 mph French Train a Grande Vitesse (TGV) in the Texas Triangle (Dallas-Fort Worth, Houston, San Antonio), with construction to begin in 1995. The report provides the Analysis (Vol. I) of results, and detailed data and statistical summaries (Vol. II, Appendices) of representative electric and magnetic field (EMF) profiles on TGV-A trains between Paris and Tours formore » two electro-technologies (1.5 KV DC near Paris, and 2x25 KV at 50 Hz AC).« less

Safety of high speed guided ground transportation systems. Magnetic and electric field testing of the French Train a Grande Vitesse (TGV) rail systems. Volume 2. Appendices. Final report, September 1992-March 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dietrich, F.M.; Jacobs, W.E.

The safety of magnetically levitated (maglev) and high speed rail (HSR) trains proposed for application in the United States is the responsibility of the Federal Railroad Administration (FRA). A franchise has been awarded to the Texas High Speed Rail Corporation to operate a 200 mph French Train a Grande Vitesse (TGV) in the Texas Triangle (Dallas-Fort Worth, Houston, San Antonio), with construction to begin in 1995. The report provides the Analysis (Vol. I) of results, and detailed data and statistical summaries (Vol. II, Appendices) of representative electric and magnetic field (EMF) profiles on TGV-A trains between Paris and Tours formore » two electro-technologies (1.5 KV DC near Paris, and 2x25 KV at 50 Hz AC).« less

Nonlinear optical modulation in a plasmonic Bi:YIG Mach-Zehnder interferometer

NASA Astrophysics Data System (ADS)

Firby, C. J.; Elezzabi, A. Y.

2017-02-01

In this work, we propose a magnetoplasmonic modulator for nonlinear radio-frequency (RF) modulation of an integrated optical signal. The modulator consists of a plasmonic Mach-Zehnder interferometer (MZI), constructed of the ferrimagnetic garnet, bismuth-substituted yttrium iron garnet (Bi:YIG). The transverse component of the Bi:YIG magnetization induces a nonreciprocal phase shift (NRPS) onto the guided optical mode, which can be actively modulated through external magnetic fields. In an MZI, the modulated phase shift in turn modulates the output optical intensity. Due to the highly nonlinear evolution of the Bi:YIG magnetization, we show that the spectrum of the output modulated intensity signal can contain harmonics of the driving RF field, frequency splitting around the driving frequency, down-conversion, or mixing of multiple RF signals. This device provides a unique mechanism of simultaneously generating a number of modulation frequencies within a single device.

Gauge-free gyrokinetic theory

NASA Astrophysics Data System (ADS)

Burby, Joshua; Brizard, Alain

2017-10-01

Test-particle gyrocenter equations of motion play an essential role in the diagnosis of turbulent strongly-magnetized plasmas, and are playing an increasingly-important role in the formulation of kinetic-gyrokinetic hybrid models. Previous gyrocenter models required the knowledge of the perturbed electromagnetic potentials, which are not directly observable quantities (since they are gauge-dependent). A new gauge-free formulation of gyrocenter motion is presented, which enables gyrocenter trajectories to be determined using only measured values of the directly-observable electromagnetic field. Our gauge-free gyrokinetic theory is general enough to allow for gyroradius-scale fluctuations in both the electric and magnetic field. In addition, we provide gauge-free expressions for the charge and current densities produced by a distribution of gyrocenters, which explicitly include guiding-center and gyrocenter polarization and magnetization effects. This research was supported by the U.S. DOE Contract Nos. DE-SC0014032 (AB) and DE-AC05-06OR23100 (JB).

Computed tomography and magnetic resonance imaging in diagnosing hepatocellular carcinoma.

PubMed

Dalla Palma, L; Pozzi-Mucelli, R S

1992-02-01

The evaluation of hepatocellular carcinoma (HCC) is based upon ultrasonography (US) which has proved to have a high sensitivity and is also extremely useful in guiding the percutaneous needle biopsy. The main role of computed tomography (CT) and magnetic resonance imaging (MRI) is to supplement US in evaluating the extent of HCC. The Authors discuss the different techniques of examinations of the liver both for CT and MRI as far as the modalities of contrast enhancement, site of injection, and type of contrast agents are concerned. The differences between low field and high field magnets are also discussed. The main CT and MRI findings are illustrated, depending upon the technique of examination. Finally the role of these techniques is discussed. Based upon personal experience and the data in CT literature, and if performed with updated technology and intraarterial injection (lipiodol), CT is the method of choice in order to supplement US in the evaluation of HCC.

Forecasting intense geomagnetic activity using interplanetary magnetic field data

NASA Astrophysics Data System (ADS)

Saiz, E.; Cid, C.; Cerrato, Y.

2008-12-01

Southward interplanetary magnetic fields are considered traces of geoeffectiveness since they are a main agent of magnetic reconnection of solar wind and magnetosphere. The first part of this work revises the ability to forecast intense geomagnetic activity using different procedures available in the literature. The study shows that current methods do not succeed in making confident predictions. This fact led us to develop a new forecasting procedure, which provides trustworthy results in predicting large variations of Dst index over a sample of 10 years of observations and is based on the value Bz only. The proposed forecasting method appears as a worthy tool for space weather purposes because it is not affected by the lack of solar wind plasma data, which usually occurs during severe geomagnetic activity. Moreover, the results obtained guide us to provide a new interpretation of the physical mechanisms involved in the interaction between the solar wind and the magnetosphere using Faraday's law.

Contact force with magnetic-guided catheter ablation.

PubMed

Bessière, Francis; Zikry, Christopher; Rivard, Lena; Dyrda, Katia; Khairy, Paul

2018-05-01

Achieving adequate catheter tip-tissue contact is essential for delivering robust radiofrequency (RF) ablation lesions. We measured the contact force generated by a remote magnetic-guided catheter navigation system. A plexiglass model with an integrated scale was fashioned to mimic transvenous and retrograde access to sites in the right atrium and right and left ventricles. An 8 Fr RF ablation catheter was steered by remote magnetic guidance at fields of 0.08 and 0.10 T, with and without a long sheath positioned at the entrance of the chamber. Ten contact force readings were taken at each setting, with the scale recalibrated prior to each measurement. Generalized estimating equations were used to compare contact force measurements while adjusting for the non-independent data structure. A total of 240 contact force measurements were taken. Without a long sheath, contact forces with magnetic fields of 0.10 T (n = 60) and 0.08 T (n = 60) were similar (6.1 ± 1.4 g vs. 6.0 ± 1.3 g, P = 0.089). Contact forces were not significantly different with simulated transvenous (n = 80) and retrograde aortic (n = 40) approaches (6.2 ± 1.4 g vs. 5.7 ± 1.2 g, P = 0.132). The contact force increased substantially with a long sheath (P < 0.001) and was significantly higher with 0.10 T (n = 60) vs. 0.08 T (n = 60) fields (20.4 ± 0.6 g vs. 18.0 ± 0.5 g, P < 0.001). Magnetic fields of 0.08 and 0.10 T provide stable catheter contact forces, as reflected by the small variability between measurements. The average contact force is approximately 6 g without a sheath and increases to 20 g with a long sheath positioned at the entrance of the chamber of interest.

Technical Note: Magnetic field effects on Gafchromic-film response in MR-IGRT.

PubMed

Reynoso, Francisco J; Curcuru, Austen; Green, Olga; Mutic, Sasa; Das, Indra J; Santanam, Lakshmi

2016-12-01

Magnetokinetic changes may affect crystal orientation and polymerization within the active layer of radiochromic film (RCF). This effect is investigated in a magnetic resonance image-guided radiotherapy unit within the context of film dosimetry. Gafchromic EBT2 RCF was irradiated in a 30 × 30 × 30 cm 3 solid water phantom using a Co-60 MRI guided radiotherapy system (B = 0.35 T) under normal operating conditions, and under the exact conditions and setup without a magnetic field. Fifteen 20.3 × 25.4 cm 2 EBT2 film sheets were placed at three different depths (d = 0.5, 5, and 10 cm) using five different treatment plans. The plans were computed using the MRIdian (ViewRay, Inc.) treatment planning system to deliver doses between 0 and 17.6 Gy. Films were analyzed before and after irradiation to obtain the net optical density (netOD) for each color channel separately. Scanning electron microscope (SEM) images were obtained to compare the active layer of selected samples. The results indicated that the red channel netOD decreased between 0.013 and 0.123 (average of 0.060 ± 0.033) for doses above 2.8 Gy, with a linear increase in this effect for higher doses. Green channel netOD showed similar results with a decrease between 0.012 and 0.105 (average of 0.041 ± 0.027) for doses above 3.5 Gy. The blue channel showed the weakest effect with a netOD decrease between 0.013 and 0.029 (average of 0.020 ± 0.006) for doses above 8.0 Gy. SEM images show changes in crystal orientation within active layer in RCF exposed in a magnetic field. The presence of a magnetic field affects crystal orientation and polymerization during irradiation, where netOD decreased by an average of 8.7%, 8.0%, and 4.3% in the red, green, and blue channels, respectively. The under response was dependent on dose and differed by up to 15% at 17.6 Gy.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singh, K. A. P.; Nishida, K.; Shibata, K.

The Solar Optical Telescope (SOT) on board Hinode allows observations with high spatiotemporal resolution and stable image quality. A {lambda}-shaped chromospheric anemone jet was observed in high resolution with SOT/Hinode. We found that several fine-scale jets were launched from one end of the footpoint to the other. These fine-scale jets ({approx}1.5-2.5 Mm) gradually move from one end of the footpoint to the other and finally merge into a single jet. This process occurs recurrently, and as time progresses the jet activity becomes more and more violent. The time evolution of the region below the jet in Ca II H filtergrammore » images taken with SOT shows that various parts (or knots) appear at different positions. These bright knots gradually merge into each other during the maximum phase. The systematic motion of the fine-scale jets is observed when different knots merge into each other. Such morphology would arise due to the emergence of a three-dimensional twisted flux rope in which the axial component (or the guide field) appears in the later stages of the flux rope emergence. The partial appearance of the knots could be due to the azimuthal magnetic field that appears during the early stage of the flux rope emergence. If the guide field is strong and reconnection occurs between the emerging flux rope and an ambient magnetic field, this could explain the typical feature of systematic motion in chromospheric anemone jets.« less

New description of charged particle propagation in random magnetic fields

NASA Technical Reports Server (NTRS)

Earl, James A.

1994-01-01

When charged particles spiral along a large constant magnetic field, their trajectories are scattered by random components that are superposed on the guiding field. In the simplest analysis of this situation, scattering causes the particles to diffuse parallel to the guiding field. At the next level of approximation, moving pulses that correspond to a coherent mode of propagation are present, but they are represented by delta-functions whose infinitely narrow width makes no sense physically and is inconsistent with the finite duration of coherent pulses observed in solar energetic particle events. To derive a more realistic description, the transport problem is formulated in terms of 4 x 4 matrices, which derive from a representation of the particle distribution function in terms of eigenfunctions of the scattering operator, and which lead to useful approximations that give explicit predictions of the detailed evolution not only of the coherent pulses, but also of the diffusive wake. More specifically, the new description embodies a simple convolution of a narrow Gaussian with the solutions above that involve delta-functions, but with a slightly reduced coherent velocity. The validity of these approximations, which can easily be calculated on a desktop computer, has been exhaustively confirmed by comparison with results of Monte Carlo simulations which kept track of 50 million particles and which were carried out on the Maspar computer at Goddard Space Flight Center.

Voltage control of nanoscale magnetoelastic elements: theory and experiments (Presentation Recording)

NASA Astrophysics Data System (ADS)

Carman, Gregory P.

2015-09-01

Electromagnetic devices rely on electrical currents to generate magnetic fields. While extremely useful this approach has limitations in the small-scale. To overcome the scaling problem, researchers have tried to use electric fields to manipulate a magnetic material's intrinsic magnetization (i.e. multiferroic). The strain mediated class of multiferroics offers up to 70% of energy transduction using available piezoelectric and magnetoelastic materials. While strain mediated multiferroic is promising, few studies exist on modeling/testing of nanoscale magnetic structures. This talk presents motivation, analytical models, and experimental data on electrical control of nanoscale single magnetic domain structures. This research is conducted in a NSF Engineering Research Center entitled Translational Applications for Nanoscale Multiferroics TANMS. The models combine micromagnetics (Landau-Lifshitz-Gilbert) with elastodynamics using the electrostatic approximation producing eight fully coupled nonlinear partial differential equations. Qualitative and quantitative verification is achieved with direct comparison to experimental data. The modeling effort guides fabrication and testing on three elements, i.e. nanoscale rings (onion states), ellipses (single domain reorientation), and superparamagnetic elements. Experimental results demonstrate electrical and deterministic control of the magnetic states in the 5-500 nm structures as measured with Photoemission Electron Microscopy PEEM, Magnetic Force Microscopy MFM, or Lorentz Transmission Electron Microscopy TEM. These data strongly suggests efficient control of nanoscale magnetic spin states is possible with voltage.

Highly efficient magnetic targeting of mesenchymal stem cells in spinal cord injury

PubMed Central

Vaněček, Václav; Zablotskii, Vitalii; Forostyak, Serhiy; Růřička, Jiří; Herynek, Vít; Babič, Michal; Jendelová, Pavla; Kubinová, Šárka; Dejneka, Alexandr; Syková, Eva

2012-01-01

The transplantation of mesenchymal stem cells (MSC) is currently under study as a therapeutic approach for spinal cord injury, and the number of transplanted cells that reach the lesioned tissue is one of the critical parameters. In this study, intrathecally transplanted cells labeled with superparamagnetic iron oxide nanoparticles were guided by a magnetic field and successfully targeted near the lesion site in the rat spinal cord. Magnetic resonance imaging and histological analysis revealed significant differences in cell numbers and cell distribution near the lesion site under the magnet in comparison to control groups. The cell distribution correlated well with the calculated distribution of magnetic forces exerted on the transplanted cells in the subarachnoid space and lesion site. The kinetics of the cells’ accumulation near the lesion site is described within the framework of a mathematical model that reveals those parameters critical for cell targeting and suggests ways to enhance the efficiency of magnetic cell delivery. In particular, we show that the targeting efficiency can be increased by using magnets that produce spatially modulated stray fields. Such magnetic systems with tunable geometric parameters may provide the additional level of control needed to enhance the efficiency of stem cell delivery in spinal cord injury. PMID:22888231

Numerical simulation of runaway electrons: 3-D effects on synchrotron radiation and impurity-based runaway current dissipation

NASA Astrophysics Data System (ADS)

del-Castillo-Negrete, D.; Carbajal, L.; Spong, D.; Izzo, V.

2018-05-01

Numerical simulations of runaway electrons (REs) with a particular emphasis on orbit dependent effects in 3-D magnetic fields are presented. The simulations were performed using the recently developed Kinetic Orbit Runaway electron Code (KORC) that computes the full-orbit relativistic dynamics in prescribed electric and magnetic fields including radiation damping and collisions. The two main problems of interest are synchrotron radiation and impurity-based RE dissipation. Synchrotron radiation is studied in axisymmetric fields and in 3-D magnetic configurations exhibiting magnetic islands and stochasticity. For passing particles in axisymmetric fields, neglecting orbit effects might underestimate or overestimate the total radiation power depending on the direction of the radial shift of the drift orbits. For trapped particles, the spatial distribution of synchrotron radiation exhibits localized "hot" spots at the tips of the banana orbits. In general, the radiation power per particle for trapped particles is higher than the power emitted by passing particles. The spatial distribution of synchrotron radiation in stochastic magnetic fields, obtained using the MHD code NIMROD, is strongly influenced by the presence of magnetic islands. 3-D magnetic fields also introduce a toroidal dependence on the synchrotron spectra, and neglecting orbit effects underestimates the total radiation power. In the presence of magnetic islands, the radiation damping of trapped particles is larger than the radiation damping of passing particles. Results modeling synchrotron emission by RE in DIII-D quiescent plasmas are also presented. The computation uses EFIT reconstructed magnetic fields and RE energy distributions fitted to the experimental measurements. Qualitative agreement is observed between the numerical simulations and the experiments for simplified RE pitch angle distributions. However, it is noted that to achieve quantitative agreement, it is necessary to use pitch angle distributions that depart from simplified 2-D Fokker-Planck equilibria. Finally, using the guiding center orbit model (KORC-GC), a preliminary study of pellet mitigated discharges in DIII-D is presented. The dependence of RE energy decay and current dissipation on initial energy and ionization levels of neon impurities is studied. The computed decay rates are within the range of experimental observations.

Recommendations for Guidelines for Environment-Specific Magnetic-Field Measurements, Rapid Program Engineering Project #2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Electric Research and Management, Inc.; IIT Research Institute; Magnetic Measurements

1997-03-11

The purpose of this project was to document widely applicable methods for characterizing the magnetic fields in a given environment, recognizing the many sources co-existing within that space. The guidelines are designed to allow the reader to follow an efficient process to (1) plan the goals and requirements of a magnetic-field study, (2) develop a study structure and protocol, and (3) document and carry out the plan. These guidelines take the reader first through the process of developing a basic study strategy, then through planning and performing the data collection. Last, the critical factors of data management, analysis reporting, andmore » quality assurance are discussed. The guidelines are structured to allow the researcher to develop a protocol that responds to specific site and project needs. The Research and Public Information Dissemination Program (RAPID) is based on exposure to magnetic fields and the potential health effects. Therefore, the most important focus for these magnetic-field measurement guidelines is relevance to exposure. The assumed objective of an environment-specific measurement is to characterize the environment (given a set of occupants and magnetic-field sources) so that information about the exposure of the occupants may be inferred. Ideally, the researcher seeks to obtain complete or "perfect" information about these magnetic fields, so that personal exposure might also be modeled perfectly. However, complete data collection is not feasible. In fact, it has been made more difficult as the research field has moved to expand the list of field parameters measured, increasing the cost and complexity of performing a measurement and analyzing the data. The guidelines address this issue by guiding the user to design a measurement protocol that will gather the most exposure-relevant information based on the locations of people in relation to the sources. We suggest that the "microenvironment" become the base unit of area in a study, with boundaries defined by the occupant's activity patterns and the field variation from the sources affecting the area. Such a stratification allows the researcher to determine which microenvironment are of most interest, and to methodically focus the areas, in order to gather the most relevant set of data.« less

The Role of Fluid Compression in Particle Energization during Magnetic Reconnection

NASA Astrophysics Data System (ADS)

Li, X.; Guo, F.; Li, H.; Li, S.

2017-12-01

Theories of particle transport and acceleration have shown that fluid compression is the leading mechanism for particle energization. However, the role of compression in particle energization during magnetic reconnection is unclear. We present a cluster of studies to clarify and show the effect of fluid compression in accelerating particles to high energies during magnetic reconnection. Using fully kinetic reconnection simulations, we show that fluid compression is the leading mechanism for high-energy particle energization. We find that the compressional energization is more important in a low-beta plasma or in a reconnection layer with a weak guide field (the magnetic field component perpendicular to the reconnecting magnetic field), which are relevant to solar flares. Our analysis on 3D kinetic simulations shows that the self-generated turbulence scatters particles and enhances the particle diffusion processes in the acceleration regions. Based on these results, we then study large-scale reconnection acceleration by solving the particle transport equation in a large-scale reconnection layer evolved with MHD simulations. Due to the compressional effect, particles are accelerated to high energies and develop power-law energy distributions. This study clarifies the nature of particle acceleration in reconnection layer and is important to understand particle energization during large-scale acceleration such as solar flares.

Reconnection Mediated by Magnetic Fractures and the Solar Flare

NASA Astrophysics Data System (ADS)

Haerendel, Gerhard

2018-03-01

Reconnection of sheared magnetic fields is commonly treated by regarding the component perpendicular to the antiparallel components as a largely inert guide field. In this paper an alternative is proposed in which the free energy residing in the shear field is being converted prior to reconnection. This happens in high-density, dissipative current sheets bordering the reconnection site. A global scenario is presented in which low-intensity currents out of the photosphere are converging into the narrow, high-intensity currents at high altitude. This is enabled by the obliqueness of the latter. The very short timescale of the energy conversion causes a lateral propagation of the current sheets. In a quasi-stationary situation, it balances the reconnection rate, which turns out to be much lower than in guide-field approaches. Another important consequence of the obliqueness is the field-parallel emission of runaway electrons. Accelerated up to tens of keV, they are possibly important contributors to the production of hard X-rays during the impulsive phase of a flare, but only in areas of upward-directed currents. Quantitative evaluation of the model predicts various potentially observable properties, such as width and propagation speed of the generated flare ribbons, spatial dependences of the electron spectrum, size of the area of energy deposition, and successive decrease of the shear angle between conjugate footpoints. The presented theoretical model can account for the observed brightness asymmetry of flare ribbons with respect to the direction of the vertical currents.

Magnetic Carbon nanoparticles enabled efficient photothermal alteration of mammalian cells

NASA Astrophysics Data System (ADS)

Cardenas, Nelson; Thomas, Patrick; Yu, Lingfeng; Mohanty, Samarendra

2011-03-01

While cw near-infrared (NIR) laser beams have been finding widespread application in photothermal therapy of cancer and pulsed NIR laser microbeams are recently being used for optoporation of exogeneous impermeable materials into cells. Since, carbon nanomaterials are very good in photothermal conversion, we utilized carbon nanoparticles (CNP) doped with Fe, so that they can be localized in a defined area by two fold selectivity, (i) external magnetic field for retention of the CNP in targeted area and (ii) surface functionalization for binding the targeted cells. Here, we report efficient photothermal therapy as well as poration of cells using magnetic CNPs with very low power continuous wave laser beam. Localization of CNPs on cell membrane under application of magnetic field was confirmed by scanning electron microscopy. At different power levels, cells could be damaged or microinjected with fluorescence protein-encoding plasmids or impermeable dyes. Monte Carlo simulation showed that the dose of NIR laser beam is sufficient to elicit response for magnetic CNP based photothermal treatment at significant depth. The results of our study suggest that magnetic CNP based photothermal alteration is a viable approach to remotely guide treatments offering high efficiency with significantly reduced cytotoxicity.

Two-fluid and magnetohydrodynamic modelling of magnetic reconnection in the MAST spherical tokamak and the solar corona

NASA Astrophysics Data System (ADS)

Browning, P. K.; Cardnell, S.; Evans, M.; Arese Lucini, F.; Lukin, V. S.; McClements, K. G.; Stanier, A.

2016-01-01

Twisted magnetic flux ropes are ubiquitous in laboratory and astrophysical plasmas, and the merging of such flux ropes through magnetic reconnection is an important mechanism for restructuring magnetic fields and releasing free magnetic energy. The merging-compression scenario is one possible start-up scheme for spherical tokamaks, which has been used on the Mega Amp Spherical Tokamak (MAST). Two current-carrying plasma rings or flux ropes approach each due to mutual attraction, forming a current sheet and subsequently merge through magnetic reconnection into a single plasma torus, with substantial plasma heating. Two-dimensional resistive and Hall-magnetohydrodynamic simulations of this process are reported, including a strong guide field. A model of the merging based on helicity-conserving relaxation to a minimum energy state is also presented, extending previous work to tight-aspect-ratio toroidal geometry. This model leads to a prediction of the final state of the merging, in good agreement with simulations and experiment, as well as the average temperature rise. A relaxation model of reconnection between two or more flux ropes in the solar corona is also described, allowing for different senses of twist, and the implications for heating of the solar corona are discussed.

Static and dynamic parasitic magnetizations and their control in superconducting accelerator dipoles

NASA Astrophysics Data System (ADS)

Collings, E. W.; Sumption, M. D.

2001-05-01

Long dipole magnets guide the particle beams in synchrotron-type high energy accelerators. In principal Cu-wound DC-excited dipoles could be designed to deliver a very uniform transverse bore field, i.e. with small or negligible harmonic (multipolar) distortion. But if the Cu is replaced by (a) superconducting strand that is (b) wound into a Rutherford cable carrying a time-varying transport current, extra magnetizations present within the windings cause distortions of the otherwise uniform field. The static (persistent-current) strand magnetization can be reduced by reducing the filament diameter, and the residue compensated or corrected by strategically placed active or passive components. The cable’s interstrand coupling currents can be controlled by increasing the interstrand contact resistance by: adjusting the level of native oxidation of the strand, coating it, or by inserting a ribbon-like core into the cable itself. Methods of locally compensating the magnetization of NbTi and Nb 3Sn strand and cable are discussed, progress in coupling-current suppression through the use of coatings and cores is reviewed, and a method of simultaneously reducing both the static and dynamic magnetizations of a NbTi cable by means of a thin Ni core is suggested.

TH-AB-BRA-11: Using 3D Dosimeters for the Investigation of the Electron Return Effect (ERE) in MR-Guided Radiation Therapy: A Feasibility Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Choi, G; Lee, H; Alqathami, M

Purpose: To demonstrate the capability of 3D radiochromic PRESAGE and Fricke-type dosimeters to measure the influence of magnetic fields on dose distribution, including the electron return effect (ERE), for MR-guided radiation therapy applications. Methods: Short cylindrical 3D dosimeters with PRESAGE and Fricke-type formulations were created in-house prior to irradiations in a 1.5T/7MV MR-linac. Each dosimeter was prepared with a concentric cylindrical air cavity with diameters of 1.5 cm and 2.5 cm, and the diameters of the dosimeters were 7.2 cm and 8.8 cm for PRESAGE and Fricke-type respectively. The dosimeters were irradiated within the bore of the MR-linac with themore » flat face of the dosimeters perpendicular to the magnetic field. Dosimeters were irradiated to approximately 9 Gy and 29 Gy to the center of dosimeters with a 15×15 cm{sup 2} field. The PRESAGE dosimeter was scanned using an optical-CT 2 hours post-irradiation; the Fricke-type dosimeter was immediately imaged with the MR component of the MR-linac post-irradiation. Results: Axial slices of the dose distributions show a clear demonstration of the dose enhancement due to the ERE above the cavity and the region of reduced dose below the cavity. The regions of increased and reduced dose are rotated with respect to the radiation beam axis due to the average directional change of the electrons. Measurements from line profiles show the dose enhanced up to ∼0.5 cm around the cavity by up to a factor of 1.3 and 1.4 for PRESAGE and Fricke-type dosimeters respectively. Conclusion: PRESAGE and Fricke-type dosimeters are able to qualitatively measure the ERE with good agreement with previously published simulation and 2D dosimetry demonstrations of the ERE. Further investigation of these 3D dosimeters as promising candidates for quality assurance of MR-guided radiation therapy systems is encouraged to assess changes in response and measurement accuracy due to the magnetic field.« less

Charged particle tracking without magnetic field: Optimal measurement of track momentum by a Bayesian analysis of the multiple measurements of deflections due to multiple scattering

NASA Astrophysics Data System (ADS)

Frosini, Mikael; Bernard, Denis

2017-09-01

We revisit the precision of the measurement of track parameters (position, angle) with optimal methods in the presence of detector resolution, multiple scattering and zero magnetic field. We then obtain an optimal estimator of the track momentum by a Bayesian analysis of the filtering innovations of a series of Kalman filters applied to the track. This work could pave the way to the development of autonomous high-performance gas time-projection chambers (TPC) or silicon wafer γ-ray space telescopes and be a powerful guide in the optimization of the design of the multi-kilo-ton liquid argon TPCs that are under development for neutrino studies.

On improved confinement in mirror plasmas by a radial electric field

NASA Astrophysics Data System (ADS)

Ågren, O.; Moiseenko, V. E.

2017-11-01

A weak radial electric field can suppress radial excursions of a guiding center from its mean magnetic surface. The physical origin of this effect is the smearing action by a poloidal E × B rotation, which tend to cancel out the inward and outward radial drifts. A use of this phenomenon may provide larger margins for magnetic field shaping with radial confinement of particles maintained in the collision free idealization. Mirror fields, stabilized by a quadrupolar field component, are of particular interest for their MHD stability and the possibility to control the quasi neutral radial electric field by biased potential plates outside the confinement region. Flux surface footprints on the end tank wall have to be traced to avoid short-circuiting between biased plates. Assuming a robust biasing procedure, moderate voltage demands for the biased plates seems adequate to cure even the radial excursions of Yushmanov ions which could be locally trapped near the mirrors. Analytical expressions are obtained for a magnetic quadrupolar mirror configuration which possesses minimal radial magnetic drifts in the central confinement region. By adding a weak controlled radial quasi-neutral electric field, the majority of gyro centers are predicted to be forced to move even closer to their respective mean magnetic surface. The gyro center radial coordinate is in such a case an accurate approximation for a constant of motion. By using this constant of motion, the analysis is in a Vlasov description extended to finite β. A correspondence between that Vlasov system and a fluid description with a scalar pressure and an electric potential is verified. The minimum B criterion is considered and implications for flute mode stability in the considered magnetic field is analyzed. By carrying out a long-thin expansion to a higher order, the validity of the calculations are extended to shorter and more compact device designs.

MR-guided radiofrequency ablation of hepatic malignancies at 1.5 T: initial results.

PubMed

Mahnken, Andreas H; Buecker, Arno; Spuentrup, Elmar; Krombach, Gabriele A; Henzler, Dietrich; Günther, Rolf W; Tacke, Josef

2004-03-01

To assess the feasibility of magnetic resonance (MR)-guided radiofrequency ablation (RFA) of hepatic malignancies using a high-field MR scanner. A total of 10 patients with 14 primary (N = 1) or secondary (N = 13) hepatic malignancies underwent MR-guided RFA using a closed-bore 1.5 T MR scanner. Lesion diameters ranged from 2.0 cm to 4.7 cm. RFA was performed using a 200-W generator in combination with a 3.5-cm LeVeen electrode applying a standardized energy protocol. RFA was technically feasible in all patients. Necrosis diameter ranged from 2.5 cm to 6.8 cm. The mean follow-up period is 12.2 (1-18) months. In nine out of 10 patients, local tumor control was achieved. For this purpose, a second CT-guided RFA was required in two patients. In four patients, multifocal hepatic tumor progression occurred, with the treated lesion remaining tumor-free in three of these patients. Two patients showed extrahepatic tumor progression. Four patients remained tumor-free. No major complications occurred. MR-guided RFA of hepatic malignancies in a closed-bore high-field MR scanner is technically feasible and safe. It can be advantageous in locations considered unfavorable for CT-guided puncture or in patients in which iodinated contrast material is contraindicated. Copyright 2004 Wiley-Liss, Inc.

Three-dimensional Tissue Culture Based on Magnetic Cell Levitation

PubMed Central

Souza, Glauco R.; Molina, Jennifer R.; Raphael, Robert M.; Ozawa, Michael G.; Stark, Daniel J.; Levin, Carly S.; Bronk, Lawrence F.; Ananta, Jeyarama S.; Mandelin, Jami; Georgescu, Maria-Magdalena; Bankson, James A.; Gelovani, Juri G.

2015-01-01

Cell culture is an essential tool for drug discovery, tissue engineering, and stem cell research. Conventional tissue culture produces two-dimensional (2D) cell growth with gene expression, signaling, and morphology that can differ from those in vivo and thus compromise clinical relevancy1–5. Here we report a three-dimensional (3D) culture of cells based on magnetic levitation in the presence of hydrogels containing gold and magnetic iron oxide (MIO) nanoparticles plus filamentous bacteriophage. This methodology allows for control of cell mass geometry and guided, multicellular clustering of different cell types in co-culture through spatial variance of the magnetic field. Moreover, magnetic levitation of human glioblastoma cells demonstrates similar protein expression profiles to those observed in human tumor xenografts. Taken together, these results suggest levitated 3D culture with magnetized phage-based hydrogels more closely recapitulates in vivo protein expression and allows for long-term multi-cellular studies. PMID:20228788

Magnetic gates and guides for superconducting vortices

DOE PAGES

Vlasko-Vlasov, V. K.; Colauto, F.; Buzdin, A. I.; ...

2017-04-04

Here, we image the motion of superconducting vortices in niobium film covered with a regular array of thin permalloy stripes. By altering the magnetization orientation in the stripes using a small in-plane magnetic field, we can tune the strength of interactions between vortices and the stripe edges, enabling acceleration or retardation of the superconducting vortices in the sample and consequently introducing strong tunable anisotropy into the vortex dynamics. We discuss our observations in terms of the attraction/repulsion between point magnetic charges carried by vortices and lines of magnetic charges at the stripe edges, and derive analytical formulas for the vortex-magneticmore » stripes coupling. Our approach demonstrates the analogy between the vortex motion regulated by the magnetic stripe array and electric carrier flow in gated semiconducting devices. Scaling down the geometrical features of the proposed design may enable controlled manipulation of single vortices, paving the way for Abrikosov vortex microcircuits and memories.« less

Magnetic gates and guides for superconducting vortices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vlasko-Vlasov, V. K.; Colauto, F.; Buzdin, A. I.

Here, we image the motion of superconducting vortices in niobium film covered with a regular array of thin permalloy stripes. By altering the magnetization orientation in the stripes using a small in-plane magnetic field, we can tune the strength of interactions between vortices and the stripe edges, enabling acceleration or retardation of the superconducting vortices in the sample and consequently introducing strong tunable anisotropy into the vortex dynamics. We discuss our observations in terms of the attraction/repulsion between point magnetic charges carried by vortices and lines of magnetic charges at the stripe edges, and derive analytical formulas for the vortex-magneticmore » stripes coupling. Our approach demonstrates the analogy between the vortex motion regulated by the magnetic stripe array and electric carrier flow in gated semiconducting devices. Scaling down the geometrical features of the proposed design may enable controlled manipulation of single vortices, paving the way for Abrikosov vortex microcircuits and memories.« less

Tribochemical Studies of Hard Carbon Films as a Function of Load and Environment

DTIC Science & Technology

2010-08-13

the wear tracks on the flat as well as the wear scar on the sphere. The BNL imaging apparatus uses a magnetic field to guide the photoemitted...from the sample surface, and the electron optics, which can filter electrons with the wrong path or energy. The BNL imaging chamber is not able to

Characterization of the onboard imaging unit for the first clinical magnetic resonance image guided radiation therapy system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hu, Yanle, E-mail: Hu.Yanle@mayo.edu; Rankine, Leith; Green, Olga L.

Purpose: To characterize the performance of the onboard imaging unit for the first clinical magnetic resonance image guided radiation therapy (MR-IGRT) system. Methods: The imaging performance characterization included four components: ACR (the American College of Radiology) phantom test, spatial integrity, coil signal to noise ratio (SNR) and uniformity, and magnetic field homogeneity. The ACR phantom test was performed in accordance with the ACR phantom test guidance. The spatial integrity test was evaluated using a 40.8 × 40.8 × 40.8 cm{sup 3} spatial integrity phantom. MR and computed tomography (CT) images of the phantom were acquired and coregistered. Objects were identifiedmore » around the surfaces of 20 and 35 cm diameters of spherical volume (DSVs) on both the MR and CT images. Geometric distortion was quantified using deviation in object location between the MR and CT images. The coil SNR test was performed according to the national electrical manufacturers association (NEMA) standards MS-1 and MS-9. The magnetic field homogeneity test was measured using field camera and spectral peak methods. Results: For the ACR tests, the slice position error was less than 0.10 cm, the slice thickness error was less than 0.05 cm, the resolved high-contrast spatial resolution was 0.09 cm, the resolved low-contrast spokes were more than 25, the image intensity uniformity was above 93%, and the percentage ghosting was less than 0.22%. All were within the ACR recommended specifications. The maximum geometric distortions within the 20 and 35 cm DSVs were 0.10 and 0.18 cm for high spatial resolution three-dimensional images and 0.08 and 0.20 cm for high temporal resolution two dimensional cine images based on the distance-to-phantom-center method. The average SNR was 12.0 for the body coil, 42.9 for the combined torso coil, and 44.0 for the combined head and neck coil. Magnetic field homogeneities at gantry angles of 0°, 30°, 60°, 90°, and 120° were 23.55, 20.43, 18.76, 19.11, and 22.22 ppm, respectively, using the field camera method over the 45 cm DSV. Conclusions: The onboard imaging unit of the first commercial MR-IGRT system meets ACR, NEMA, and vendor specifications.« less

Low-grade Glioma Surgery in Intraoperative Magnetic Resonance Imaging: Results of a Multicenter Retrospective Assessment of the German Study Group for Intraoperative Magnetic Resonance Imaging.

PubMed

Coburger, Jan; Merkel, Andreas; Scherer, Moritz; Schwartz, Felix; Gessler, Florian; Roder, Constantin; Pala, Andrej; König, Ralph; Bullinger, Lars; Nagel, Gabriele; Jungk, Christine; Bisdas, Sotirios; Nabavi, Arya; Ganslandt, Oliver; Seifert, Volker; Tatagiba, Marcos; Senft, Christian; Mehdorn, Maximilian; Unterberg, Andreas W; Rössler, Karl; Wirtz, Christian Rainer

2016-06-01

The ideal treatment strategy for low-grade gliomas (LGGs) is a controversial topic. Additionally, only smaller single-center series dealing with the concept of intraoperative magnetic resonance imaging (iMRI) have been published. To investigate determinants for patient outcome and progression-free-survival (PFS) after iMRI-guided surgery for LGGs in a multicenter retrospective study initiated by the German Study Group for Intraoperative Magnetic Resonance Imaging. A retrospective consecutive assessment of patients treated for LGGs (World Health Organization grade II) with iMRI-guided resection at 6 neurosurgical centers was performed. Eloquent location, extent of resection, first-line adjuvant treatment, neurophysiological monitoring, awake brain surgery, intraoperative ultrasound, and field-strength of iMRI were analyzed, as well as progression-free survival (PFS), new permanent neurological deficits, and complications. Multivariate binary logistic and Cox regression models were calculated to evaluate determinants of PFS, gross total resection (GTR), and adjuvant treatment. A total of 288 patients met the inclusion criteria. On multivariate analysis, GTR significantly increased PFS (hazard ratio, 0.44; P < .01), whereas "failed" GTR did not differ significantly from intended subtotal-resection. Combined radiochemotherapy as adjuvant therapy was a negative prognostic factor (hazard ratio: 2.84, P < .01). Field strength of iMRI was not associated with PFS. In the binary logistic regression model, use of high-field iMRI (odds ratio: 0.51, P < .01) was positively and eloquent location (odds ratio: 1.99, P < .01) was negatively associated with GTR. GTR was not associated with increased rates of new permanent neurological deficits. GTR was an independent positive prognostic factor for PFS in LGG surgery. Patients with accidentally left tumor remnants showed a similar prognosis compared with patients harboring only partially resectable tumors. Use of high-field iMRI was significantly associated with GTR. However, the field strength of iMRI did not affect PFS. EoR, extent of resectionFLAIR, fluid-attenuated inversion recoveryGTR, gross total resectionIDH1, isocitrate dehydrogenase 1iMRI, intraoperative magnetic resonance imagingLGG, low-grade gliomaMGMT, methylguanine-deoxyribonucleic acid methyltransferasenPND, new permanent neurological deficitOS, overall survivalPFS, progression-free survivalSTR, subtotal resectionWHO, World Health Organization.

Characterization of the onboard imaging unit for the first clinical magnetic resonance image guided radiation therapy system.

PubMed

Hu, Yanle; Rankine, Leith; Green, Olga L; Kashani, Rojano; Li, H Harold; Li, Hua; Nana, Roger; Rodriguez, Vivian; Santanam, Lakshmi; Shvartsman, Shmaryu; Victoria, James; Wooten, H Omar; Dempsey, James F; Mutic, Sasa

2015-10-01

To characterize the performance of the onboard imaging unit for the first clinical magnetic resonance image guided radiation therapy (MR-IGRT) system. The imaging performance characterization included four components: ACR (the American College of Radiology) phantom test, spatial integrity, coil signal to noise ratio (SNR) and uniformity, and magnetic field homogeneity. The ACR phantom test was performed in accordance with the ACR phantom test guidance. The spatial integrity test was evaluated using a 40.8 × 40.8 × 40.8 cm(3) spatial integrity phantom. MR and computed tomography (CT) images of the phantom were acquired and coregistered. Objects were identified around the surfaces of 20 and 35 cm diameters of spherical volume (DSVs) on both the MR and CT images. Geometric distortion was quantified using deviation in object location between the MR and CT images. The coil SNR test was performed according to the national electrical manufacturers association (NEMA) standards MS-1 and MS-9. The magnetic field homogeneity test was measured using field camera and spectral peak methods. For the ACR tests, the slice position error was less than 0.10 cm, the slice thickness error was less than 0.05 cm, the resolved high-contrast spatial resolution was 0.09 cm, the resolved low-contrast spokes were more than 25, the image intensity uniformity was above 93%, and the percentage ghosting was less than 0.22%. All were within the ACR recommended specifications. The maximum geometric distortions within the 20 and 35 cm DSVs were 0.10 and 0.18 cm for high spatial resolution three-dimensional images and 0.08 and 0.20 cm for high temporal resolution two dimensional cine images based on the distance-to-phantom-center method. The average SNR was 12.0 for the body coil, 42.9 for the combined torso coil, and 44.0 for the combined head and neck coil. Magnetic field homogeneities at gantry angles of 0°, 30°, 60°, 90°, and 120° were 23.55, 20.43, 18.76, 19.11, and 22.22 ppm, respectively, using the field camera method over the 45 cm DSV. The onboard imaging unit of the first commercial MR-IGRT system meets ACR, NEMA, and vendor specifications.

Magnetic resonance imaging guided reirradiation of recurrent and second primary head and neck cancer.

PubMed

Chen, Allen M; Cao, Minsong; Hsu, Sophia; Lamb, James; Mikaeilian, Argin; Yang, Yingli; Agazaryan, Nzhde; Low, Daniel A; Steinberg, Michael L

2017-01-01

To report a single-institutional experience using magnetic resonance imaging (MRI) guided radiation therapy for the reirradiation of recurrent and second cancers of the head and neck. Between October 2014 and August 2016, 13 consecutive patients with recurrent or new primary cancers of the head and neck that occurred in a previously irradiated field were prospectively enrolled in an institutional registry trial to investigate the feasibility and efficacy of MRI guided radiation therapy using a 0.35-T MRI scanner with a cobalt-60 radiation therapy source called the ViewRay system (ViewRay Inc., Cleveland, OH). Eligibility criteria included biopsy-proven evidence of recurrent or new primary squamous cell carcinoma of the head and neck, measurable disease, and previous radiation to >60 Gy. MRI guided reirradiation was delivered either using intensity modulated radiation therapy with conventional fractionation to a median dose of 66 Gy or stereotactic body radiation therapy (SBRT) using 7 to 8 Gy fractions on nonconsecutive days to a median dose of 40 Gy. Two patients (17%) received concurrent chemotherapy. The 1- and 2-year estimates of in-field control were 72% and 72%, respectively. A total of 227 daily MRI scans were obtained to guide reirradiation. The 2-year estimates of overall survival and progression-free survival were 53% and 59%, respectively. There were no treatment-related fatalities or hospitalizations. Complications included skin desquamation, odynophagia, otitis externa, keratitis and/or conjunctivitis, and 1 case of aspiration pneumonia. Our preliminary findings show that reirradiation with MRI guided radiation therapy results in effective disease control with relatively low morbidity for patients with recurrent and second primary cancers of the head and neck. The superior soft tissue resolution of the MRI scans that were used for planning and delivery has the potential to improve the therapeutic ratio.

Global electrostatic potential structures of merging flux tubes in TS-U torus plasma merging experiment

NASA Astrophysics Data System (ADS)

Sawada, Asuka; Hatano, Hironori; Akimitsu, Moe; Cao, Qinghong; Yamasaki, Kotaro; Tanabe, Hiroshi; Ono, Yasushi; TS-Group Team

2017-10-01

We have been investigating 2D potential profile of global merging tokamaks to solve high-power heating of magnetic reconnection in TS-3 and TS-3U (ST, FRC:R =0.2m, 1985-, 2017-) and TS-4 (ST, FRC:R =0.5m, 2000-), UTST (ST:R =0.45m, 2008-) and MAST (ST:R = 0.9m, 2000-) devices. These experiments made clear that the electrostatic potential well is formed not only in the downstream area of magnetic reconnection but also in the whole common (reconnected) flux area of two merging flux tubes: tokamak plasmas. This fact suggests that the ion acceleration/heating occurs in much wider region than the reconnection downstream. We studied how the potential structure depends on key reconnection parameters:guide toroidal field and plasma collisionality. We found the polarity of the guide toroidal field determines those of potential hills and wells, indicating their formation is affected by the Hall effect. The peak value of the electrostatic potential well decreased with gas pressure increasing, suggesting plasma collisionality suppresses the Hall effect. The relationship between the electrostatic potential structure and anomalous ion heating is being studied as a possible cause for the high-power heating of fast magnetic reconnection. This work was supported by JSPS KAKENHI Grant Numbers 15H05750, 15K14279 and 17H04863.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mutic, S; Low, D; Chmielewski, T

Purpose: To describe the design and characteristics of a novel linac-based MRI guided radiation therapy system that addresses RF and magnetic field interference and that can be housed in conventional radiotherapy vaults. Methods: The MR-IGRT system will provide simultaneous MR imaging combined with both simple (3D) and complex (IMRT, SBRT, SRS) techniques. The system is a combination of a) double-donut split solenoidal superconducting 0.345T MRI; and b) a 90 cm isocenter ring-gantry mounted 6MV, flattening filter-free linac coupled with a stacked doubly-focused multileaf collimator with 4 mm resolution. A novel RF shielding and absorption technology was developed to isolate themore » beam generating RF emissions from the MR, while a novel magnetic shielding sleeve system was developed to place the magnetic field-sensitive components in low-magnetic field regions. The system design produces high spatial resolution radiation beams with state-of-the art radiation dose characteristics and simultaneous MR imaging. Results: Prototype testing with a spectrum analyzer has demonstrated complete elimination of linac RF inside the treatment room. The magnetic field inside of the magnetic shielding was well below the specification, allowing the linear accelerator to operate normally. A novel on-gantry shimming system maintained < 25 ppm magnetic field homogeneity over a 45 cm spherical field of view for all gantry angles. Conclusion: The system design demonstrates the feasibility coupling a state-of-the art linac system with a 0.345T MRI, enabling highly conformal radiation therapy with simultaneous MR image guidance. S. Mutic’s employer (Washington University) has grant with ViewRay; D. Low is former ViewRay scientific advisory board member (ended October 2015); T. Chmielewski, G. Fought, M. Hernandez, I. Kawrakow, A. Sharma, S. Shvartsman, J. Dempsey are employees of ViewRay with stock options (Dempsey has leadership role and Dempsey/Kawrakow have stock).« less

Magnetic reconnection in 3D magnetosphere models: magnetic separators and open flux production

NASA Astrophysics Data System (ADS)

Glocer, A.; Dorelli, J.; Toth, G.; Komar, C. M.; Cassak, P.

2014-12-01

There are multiple competing definitions of magnetic reconnection in 3D (e.g., Hesse and Schindler [1988], Lau and Finn [1990], and Boozer [2002]). In this work we focus on separator reconnection. A magnetic separator can be understood as the 3D analogue of a 2D x line with a guide field, and is defined by the line corresponding to the intersection of the separatrix surfaces associated with the magnetic nulls. A separator in the magnetosphere represents the intersection of four distinct magnetic topologies: solar wind, closed, open connected to the northern hemisphere, and open connected to the southern hemisphere. The integral of the parallel electric field along the separator defines the rate of open flux production, and is one measure of the reconnection rate. We present three methods for locating magnetic separators and apply them to 3D resistive MHD simulations of the Earth's magnetosphere using the BATS-R-US code. The techniques for finding separators and determining the reconnection rate are insensitive to IMF clock angle and can in principle be applied to any magnetospheric model. The present work examines cases of high and low resistivity, for two clock angles. We also examine the separator during Flux Transfer Events (FTEs) and Kelvin-Helmholtz instability.

Reconnection properties in Kelvin-Helmholtz instabilities

NASA Astrophysics Data System (ADS)

Vernisse, Y.; Lavraud, B.; Eriksson, S.; Gershman, D. J.; Dorelli, J.; Pollock, C. J.; Giles, B. L.; Aunai, N.; Avanov, L. A.; Burch, J.; Chandler, M. O.; Coffey, V. N.; Dargent, J.; Ergun, R.; Farrugia, C. J.; Genot, V. N.; Graham, D.; Hasegawa, H.; Jacquey, C.; Kacem, I.; Khotyaintsev, Y. V.; Li, W.; Magnes, W.; Marchaudon, A.; Moore, T. E.; Paterson, W. R.; Penou, E.; Phan, T.; Retino, A.; Schwartz, S. J.; Saito, Y.; Sauvaud, J. A.; Schiff, C.; Torbert, R. B.; Wilder, F. D.; Yokota, S.

2017-12-01

Kelvin-Helmholtz instabilities are particular laboratories to study strong guide field reconnection processes. In particular, unlike the usual dayside magnetopause, the conditions across the magnetopause in KH vortices are quasi-symmetric, with low differences in beta and magnetic shear angle. We study these properties by means of statistical analysis of the high-resolution data of the Magnetospheric Multiscale mission. Several events of Kelvin-Helmholtz instabilities pas the terminator plane and a long lasting dayside instabilities event where used in order to produce this statistical analysis. Early results present a consistency between the data and the theory. In addition, the results emphasize the importance of the thickness of the magnetopause as a driver of magnetic reconnection in low magnetic shear events.

TH-AB-BRA-09: Stability Analysis of a Novel Dose Calculation Algorithm for MRI Guided Radiotherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zelyak, O; Fallone, B; Cross Cancer Institute, Edmonton, AB

2016-06-15

Purpose: To determine the iterative deterministic solution stability of the Linear Boltzmann Transport Equation (LBTE) in the presence of magnetic fields. Methods: The LBTE with magnetic fields under investigation is derived using a discrete ordinates approach. The stability analysis is performed using analytical and numerical methods. Analytically, the spectral Fourier analysis is used to obtain the convergence rate of the source iteration procedures based on finding the largest eigenvalue of the iterative operator. This eigenvalue is a function of relevant physical parameters, such as magnetic field strength and material properties, and provides essential information about the domain of applicability requiredmore » for clinically optimal parameter selection and maximum speed of convergence. The analytical results are reinforced by numerical simulations performed using the same discrete ordinates method in angle, and a discontinuous finite element spatial approach. Results: The spectral radius for the source iteration technique of the time independent transport equation with isotropic and anisotropic scattering centers inside infinite 3D medium is equal to the ratio of differential and total cross sections. The result is confirmed numerically by solving LBTE and is in full agreement with previously published results. The addition of magnetic field reveals that the convergence becomes dependent on the strength of magnetic field, the energy group discretization, and the order of anisotropic expansion. Conclusion: The source iteration technique for solving the LBTE with magnetic fields with the discrete ordinates method leads to divergent solutions in the limiting cases of small energy discretizations and high magnetic field strengths. Future investigations into non-stationary Krylov subspace techniques as an iterative solver will be performed as this has been shown to produce greater stability than source iteration. Furthermore, a stability analysis of a discontinuous finite element space-angle approach (which has been shown to provide the greatest stability) will also be investigated. Dr. B Gino Fallone is a co-founder and CEO of MagnetTx Oncology Solutions (under discussions to license Alberta bi-planar linac MR for commercialization)« less

Performance of a static-anode/flat-panel x-ray fluoroscopy system in a diagnostic strength magnetic field: a truly hybrid x-ray/MR imaging system.

PubMed

Fahrig, R; Wen, Z; Ganguly, A; DeCrescenzo, G; Rowlands, J A; Stevens, G M; Saunders, R F; Pelc, N J

2005-06-01

Minimally invasive procedures are increasing in variety and frequency, facilitated by advances in imaging technology. Our hybrid imaging system (GE Apollo flat panel, custom Brand x-ray static anode x-ray tube, GE Lunar high-frequency power supply and 0.5 T Signa SP) provides both x-ray and MR imaging capability to guide complex procedures without requiring motion of the patient between two distant gantries. The performance of the x-ray tube in this closely integrated system was evaluated by modeling and measuring both the response of the filament to an externally applied field and the behavior of the electron beam for field strengths and geometries of interest. The performance of the detector was assessed by measuring the slanted-edge modulation transfer function (MTF) and when placed at zero field and at 0.5 T. Measured resonant frequencies of filaments can be approximated using a modified vibrating beam model, and were at frequencies well below the 25 kHz frequency of our generator for our filament geometry. The amplitude of vibration was not sufficient to cause shorting of the filament during operation within the magnetic field. A simple model of electrons in uniform electric and magnetic fields can be used to estimate the deflection of the electron beam on the anode for the fields of interest between 0.2 and 0.5 T. The MTF measured at the detector and the DQE showed no significant difference inside and outside of the magnetic field. With the proper modifications, an x-ray system can be fully integrated with a MR system, with minimal loss of image quality. Any x-ray tube can be assessed for compatibility when placed at a particular location within the field using the models. We have also concluded that a-Si electronics are robust against magnetic fields. Detailed knowledge of the x-ray system installation is required to provide estimates of system operation.

Heat flux modeling using ion drift effects in DIII-D H-mode plasmas with resonant magnetic perturbations

DOE PAGES

Wingen, Andreas; Schmitz, Oliver; Evans, Todd E.; ...

2014-01-01

The heat flux patterns measured in low-collisionality DIII-D H-mode plasmas strongly deviate from simultaneously measured CII emission patterns, used as indicator of particle flux, during applied resonant magnetic perturbations. While the CII emission clearly shows typical striations, which are similar to magnetic footprint patterns obtained from vacuum field line tracing, the heat flux is usually dominated by one large peak at the strike point position. The vacuum approximation, which only considers applied magnetic fields and neglects plasma response and plasma effects, cannot explain the shape of the observed heat flux pattern. One possible explanation is the effect of particle drifts.more » This is included in the field line equations and the results are discussed with reference to the measurement. Electrons and ions show di fferent drift motions at thermal energy levels in a guiding center approximation. While electrons hardly deviate from the field lines, ions can drift several centimetres away from field line flux surfaces. A model is presented in which an ion heat flux, based on the ion drift motion from various kinetic energies as they contribute to a thermal Maxwellian distribution, is calculated. The simulated heat flux is directly compared to measurements with a varying edge safety factor q95. This analysis provides evidence for the dominate e ect of high-energy ions in carrying heat from the plasma inside the separatrix to the target. High-energy ions are deposited close to the unperturbed strike line while low-energy ions can travel into the striated magnetic topology.« less

Coronal Heating: Testing Models of Coronal Heating by Forward-Modeling the AIA Emission of the Ansample of Coronal Loops

NASA Astrophysics Data System (ADS)

Malanushenko, A. V.

2015-12-01

We present a systemic exploration of the properties of coronal heating, by forward-modeling the emission of the ensemble of 1D quasi-steady loops. This approximations were used in many theoretical models of the coronal heating. The latter is described in many such models in the form of power laws, relating heat flux through the photosphere or volumetric heating to the strength of the magnetic field and length of a given field line. We perform a large search in the parameter space of these power laws, amongst other variables, and compare the resulting emission of the active region to that observed by AIA. We use a recently developed magnetic field model which uses shapes of coronal loops to guide the magnetic model; the result closely resembles observed structures by design. We take advantage of this, by comparing, in individual sub-regions of the active region, the emission of the active region and its synthetic model. This study allows us to rule out many theoretical models and formulate predictions for the heating models to come.

MR image reconstruction via guided filter.

PubMed

Huang, Heyan; Yang, Hang; Wang, Kang

2018-04-01

Magnetic resonance imaging (MRI) reconstruction from the smallest possible set of Fourier samples has been a difficult problem in medical imaging field. In our paper, we present a new approach based on a guided filter for efficient MRI recovery algorithm. The guided filter is an edge-preserving smoothing operator and has better behaviors near edges than the bilateral filter. Our reconstruction method is consist of two steps. First, we propose two cost functions which could be computed efficiently and thus obtain two different images. Second, the guided filter is used with these two obtained images for efficient edge-preserving filtering, and one image is used as the guidance image, the other one is used as a filtered image in the guided filter. In our reconstruction algorithm, we can obtain more details by introducing guided filter. We compare our reconstruction algorithm with some competitive MRI reconstruction techniques in terms of PSNR and visual quality. Simulation results are given to show the performance of our new method.

Simulation of neoclassical transport with the continuum gyrokinetic code COGENT

DOE PAGES

Dorf, M. A.; Cohen, R. H.; Dorr, M.; ...

2013-01-25

The development of the continuum gyrokinetic code COGENT for edge plasma simulations is reported. The present version of the code models a nonlinear axisymmetric 4D (R, v∥, μ) gyrokinetic equation coupled to the long-wavelength limit of the gyro-Poisson equation. Here, R is the particle gyrocenter coordinate in the poloidal plane, and v∥ and μ are the guiding center velocity parallel to the magnetic field and the magnetic moment, respectively. The COGENT code utilizes a fourth-order finite-volume (conservative) discretization combined with arbitrary mapped multiblock grid technology (nearly field-aligned on blocks) to handle the complexity of tokamak divertor geometry with high accuracy.more » Furthermore, topics presented are the implementation of increasingly detailed model collision operators, and the results of neoclassical transport simulations including the effects of a strong radial electric field characteristic of a tokamak pedestal under H-mode conditions.« less

Energy Conversion Mechanism for Electron Perpendicular Energy in High Guide-Field Reconnection

NASA Astrophysics Data System (ADS)

Guo, Xuehan; Horiuchi, Ritoku; Kaminou, Yasuhiro; Cheng, Frank; Ono, Yasushi

2016-10-01

The energy conversion mechanism for electron perpendicular energy, both the thermal and the kinetic energy, is investigated by means of two-dimensional, full-particle simulations in an open system. It is shown that electron perpendicular heating is mainly due to the breaking of magnetic moment conservation in separatrix region because the charge separation generates intense variation of electric field within the electron Larmor radius. Meanwhile, electron perpendicular acceleration takes place manly due to the polarization drift term as well as the curvature drift term of E . u⊥ in the downstream near the X-point. The enhanced electric field due to the charge separation there results in a significant effect of the polarization drift term on the dissipation of magnetic energy within the ion inertia length in the downstream. Japan Society for the Promotion of Science (JSPS) Fellows 15J03758.

Interstellar Pickup Ion Acceleration in the Turbulent Magnetic Field at the Solar Wind Termination Shock Using a Focused Transport Approach

NASA Astrophysics Data System (ADS)

Ye, Junye; le Roux, Jakobus A.; Arthur, Aaron D.

2016-08-01

We study the physics of locally born interstellar pickup proton acceleration at the nearly perpendicular solar wind termination shock (SWTS) in the presence of a random magnetic field spiral angle using a focused transport model. Guided by Voyager 2 observations, the spiral angle is modeled with a q-Gaussian distribution. The spiral angle fluctuations, which are used to generate the perpendicular diffusion of pickup protons across the SWTS, play a key role in enabling efficient injection and rapid diffusive shock acceleration (DSA) when these particles follow field lines. Our simulations suggest that variation of both the shape (q-value) and the standard deviation (σ-value) of the q-Gaussian distribution significantly affect the injection speed, pitch-angle anisotropy, radial distribution, and the efficiency of the DSA of pickup protons at the SWTS. For example, increasing q and especially reducing σ enhances the DSA rate.

Lightning Threat Analysis for the Space Shuttle Launch Pad and the Payload Changeout Room Using Finite Difference Methods

NASA Technical Reports Server (NTRS)

Collier, Richard S.

1997-01-01

This report describes finite difference computer calculations for the Space Shuttle Launch Pad which predict lightning induced electric currents and electric and magnetic fields caused by a lightning strike to the Lightning Protection System caternary wire. Description of possible lightning threats to Shuttle Payload components together with specifications for protection of these components, result from the calculation of lightning induced electric and magnetic fields inside and outside the during a lightning event. These fields also induce currents and voltages on cables and circuits which may be connected to, or a part of, shuttle payload components. These currents and voltages are also calculated. These threat levels are intended as a guide for designers of payload equipment to specify any shielding and/or lightning protection mitigation which may be required for payload components which are in the process of preparation or being transferred into the Shuttle Orbiter.

Visual but not trigeminal mediation of magnetic compass information in a migratory bird.

PubMed

Zapka, Manuela; Heyers, Dominik; Hein, Christine M; Engels, Svenja; Schneider, Nils-Lasse; Hans, Jörg; Weiler, Simon; Dreyer, David; Kishkinev, Dmitry; Wild, J Martin; Mouritsen, Henrik

2009-10-29

Magnetic compass information has a key role in bird orientation, but the physiological mechanisms enabling birds to sense the Earth's magnetic field remain one of the unresolved mysteries in biology. Two biophysical mechanisms have become established as the most promising magnetodetection candidates. The iron-mineral-based hypothesis suggests that magnetic information is detected by magnetoreceptors in the upper beak and transmitted through the ophthalmic branch of the trigeminal nerve to the brain. The light-dependent hypothesis suggests that magnetic field direction is sensed by radical pair-forming photopigments in the eyes and that this visual signal is processed in cluster N, a specialized, night-time active, light-processing forebrain region. Here we report that European robins with bilateral lesions of cluster N are unable to show oriented magnetic-compass-guided behaviour but are able to perform sun compass and star compass orientation behaviour. In contrast, bilateral section of the ophthalmic branch of the trigeminal nerve in European robins did not influence the birds' ability to use their magnetic compass for orientation. These data show that cluster N is required for magnetic compass orientation in this species and indicate that it may be specifically involved in processing of magnetic compass information. Furthermore, the data strongly suggest that a vision-mediated mechanism underlies the magnetic compass in this migratory songbird, and that the putative iron-mineral-based receptors in the upper beak connected to the brain by the trigeminal nerve are neither necessary nor sufficient for magnetic compass orientation in European robins.

Printing 1D Assembly Array of Single Particle Resolution for Magnetosensing.

PubMed

Gao, Meng; Kuang, Minxuan; Li, Lihong; Liu, Meijin; Wang, Libin; Song, Yanlin

2018-05-01

Magnetosensing is a ubiquitous ability for many organism species in nature. 1D assembly, especially that arranged in single-particle-resolution regulation, is able to sense the direction of magnetic field depending on the enhanced dipolar interaction in the linear orientation. Inspired by the magnetosome structure in magnetotactic bacteria, a 1D assembly array of single particle resolution with controlled length and well-behaved configuration is prepared via inkjet printing method assisted with magnetic guiding. In the fabrication process, chains in a "tip-to-tip" regulation with the desired number of particles are prepared in a confined tiny inkjet-printed droplet. By adjusting the receding angle of the substrate, the assembled 1D morphology is kept/deteriorated depending on the pinning/depinning behavior during ink evaporation, which leads to the formation of well-behaved 1D assembly/aggregated dot assembly. Owing to the high-aspect-ratio characteristic of the assembled structure, the as-prepared 1D arrays can be used for magnetic field sensing with anisotropic magnetization M // /M ⊥ up to 6.03. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Comparison between the Juno Earth flyby magnetic measurements and the magnetometer package on the IRIS solar observatory

NASA Astrophysics Data System (ADS)

Merayo, J. M.; Connerney, J. E.; Joergensen, J. L.; Dougherty, B.

2013-12-01

In October 2013 the NASA's Juno New Frontier spacecraft will perform an Earth Flyby Gravity Assist. During this flyby, Juno will reach an altitude of about 600 km and the magnetometer experiment will measure the magnetic field with very high precision. In June 2013 the NASA's IRIS solar observatory was successfully launched. IRIS uses a very fine guiding telescope in order to maintain a high pointing accuracy, assisted by a very high accuracy star tracker and a science grade vector magnetometer. IRIS was placed into a Sun-synchronous orbit at about 600 km altitude by a Pegasus rocket from the Vandenberg Air Force Base in California. This platform will also allow to performing measurements of the Earth's magnetic field with very high precision, since it carries similar instrumentation as on the Swarm satellites (star trackers and magnetometer). The data recorded by the Juno magnetic experiment and the IRIS magnetometer will bring a very exciting opportunity for comparing the two experiments as well as for determining current structures during the flyby.

Drifting Continents and Magnetic Fields. Crustal Evolution Education Project. Teacher's Guide [and] Student Investigation.

ERIC Educational Resources Information Center

Stoever, Edward C., Jr.

Crustal Evolution Education Project (CEEP) modules were designed to: (1) provide students with the methods and results of continuing investigations into the composition, history, and processes of the earth's crust and the application of this knowledge to man's activities and (2) to be used by teachers with little or no previous background in the…

Magnetization reversal in magnetic dot arrays: Nearest-neighbor interactions and global configurational anisotropy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Van de Wiele, Ben; Fin, Samuele; Pancaldi, Matteo

2016-05-28

Various proposals for future magnetic memories, data processing devices, and sensors rely on a precise control of the magnetization ground state and magnetization reversal process in periodically patterned media. In finite dot arrays, such control is hampered by the magnetostatic interactions between the nanomagnets, leading to the non-uniform magnetization state distributions throughout the sample while reversing. In this paper, we evidence how during reversal typical geometric arrangements of dots in an identical magnetization state appear that originate in the dominance of either Global Configurational Anisotropy or Nearest-Neighbor Magnetostatic interactions, which depends on the fields at which the magnetization reversal setsmore » in. Based on our findings, we propose design rules to obtain the uniform magnetization state distributions throughout the array, and also suggest future research directions to achieve non-uniform state distributions of interest, e.g., when aiming at guiding spin wave edge-modes through dot arrays. Our insights are based on the Magneto-Optical Kerr Effect and Magnetic Force Microscopy measurements as well as the extensive micromagnetic simulations.« less

Observation of Three-Dimensional Magnetic Reconnection in the Terrestrial Magnetotail

NASA Astrophysics Data System (ADS)

Zhou, Meng; Ashour-Abdalla, Maha; Deng, Xiaohua; Pang, Ye; Fu, Huishan; Walker, Raymond; Lapenta, Giovanni; Huang, Shiyong; Xu, Xiaojun; Tang, Rongxin

2017-09-01

Study of magnetic reconnection has been focused on two-dimensional geometry in the past decades, whereas three-dimensional structures and dynamics of reconnection X line are poorly understood. In this paper, we report Cluster multispacecraft observations of a three-dimensional magnetic reconnection X line with a weak guide field ( 25% of the upstream magnetic field) in the Earth's magnetotail. We find that the X line not only retreated tailward but also expanded across the tail following the electron flow direction with a maximum average speed of (0.04-0.15) VA,up, where VA,up is the upstream Alfvén speed, or (0.14-0.57) Vde, where Vde is the electron flow speed in the out-of-plane direction. An ion diffusion region was observed by two spacecraft that were separated about 10 ion inertial lengths along the out-of-plane direction; however, these two spacecraft observed distinct magnetic structures associated with reconnection: one spacecraft observed dipolarization fronts, while the other one observed flux ropes. This indicates that reconnection proceeds in drastically different ways in different segments along the X line only a few ion inertial lengths apart.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu Wei; Li Hui; Li Shengtai

Nonlinear ideal magnetohydrodynamic (MHD) simulations of the propagation and expansion of a magnetic ''bubble'' plasma into a lower density, weakly magnetized background plasma, are presented. These simulations mimic the geometry and parameters of the Plasma Bubble Expansion Experiment (PBEX) [A. G. Lynn, Y. Zhang, S. C. Hsu, H. Li, W. Liu, M. Gilmore, and C. Watts, Bull. Am. Phys. Soc. 52, 53 (2007)], which is studying magnetic bubble expansion as a model for extragalactic radio lobes. The simulations predict several key features of the bubble evolution. First, the direction of bubble expansion depends on the ratio of the bubble toroidalmore » to poloidal magnetic field, with a higher ratio leading to expansion predominantly in the direction of propagation and a lower ratio leading to expansion predominantly normal to the direction of propagation. Second, a MHD shock and a trailing slow-mode compressible MHD wavefront are formed ahead of the bubble as it propagates into the background plasma. Third, the bubble expansion and propagation develop asymmetries about its propagation axis due to reconnection facilitated by numerical resistivity and to inhomogeneous angular momentum transport mainly due to the background magnetic field. These results will help guide the initial experiments and diagnostic measurements on PBEX.« less

Manipulating motions of targeted single cells in solution by an integrated double-ring magnetic tweezers imaging microscope.

PubMed

Wu, Meiling; Yadav, Rajeev; Pal, Nibedita; Lu, H Peter

2017-07-01

Controlling and manipulating living cell motions in solution hold a high promise in developing new biotechnology and biological science. Here, we developed a magnetic tweezers device that employs a combination of two permanent magnets in up-down double-ring configuration axially fitting with a microscopic objective, allowing a picoNewton (pN) bidirectional force and motion control on the sample beyond a single upward pulling direction. The experimental force calibration and magnetic field simulation using finite element method magnetics demonstrate that the designed magnetic tweezers covers a linear-combined pN force with positive-negative polarization changes in a tenability of sub-pN scale, which can be utilized to further achieve motion manipulation by shifting the force balance. We demonstrate an application of the up-down double-ring magnetic tweezers for single cell manipulation, showing that the cells with internalized paramagnetic beads can be selectively picked up and guided in a controlled fine motion.

Manipulating motions of targeted single cells in solution by an integrated double-ring magnetic tweezers imaging microscope

NASA Astrophysics Data System (ADS)

Wu, Meiling; Yadav, Rajeev; Pal, Nibedita; Lu, H. Peter

2017-07-01

Controlling and manipulating living cell motions in solution hold a high promise in developing new biotechnology and biological science. Here, we developed a magnetic tweezers device that employs a combination of two permanent magnets in up-down double-ring configuration axially fitting with a microscopic objective, allowing a picoNewton (pN) bidirectional force and motion control on the sample beyond a single upward pulling direction. The experimental force calibration and magnetic field simulation using finite element method magnetics demonstrate that the designed magnetic tweezers covers a linear-combined pN force with positive-negative polarization changes in a tenability of sub-pN scale, which can be utilized to further achieve motion manipulation by shifting the force balance. We demonstrate an application of the up-down double-ring magnetic tweezers for single cell manipulation, showing that the cells with internalized paramagnetic beads can be selectively picked up and guided in a controlled fine motion.

An asymptotic-preserving Lagrangian algorithm for the time-dependent anisotropic heat transport equation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chacon, Luis; del-Castillo-Negrete, Diego; Hauck, Cory D.

2014-09-01

We propose a Lagrangian numerical algorithm for a time-dependent, anisotropic temperature transport equation in magnetized plasmas in the large guide field regime. The approach is based on an analytical integral formal solution of the parallel (i.e., along the magnetic field) transport equation with sources, and it is able to accommodate both local and non-local parallel heat flux closures. The numerical implementation is based on an operator-split formulation, with two straightforward steps: a perpendicular transport step (including sources), and a Lagrangian (field-line integral) parallel transport step. Algorithmically, the first step is amenable to the use of modern iterative methods, while themore » second step has a fixed cost per degree of freedom (and is therefore scalable). Accuracy-wise, the approach is free from the numerical pollution introduced by the discrete parallel transport term when the perpendicular to parallel transport coefficient ratio X ⊥ /X ∥ becomes arbitrarily small, and is shown to capture the correct limiting solution when ε = X⊥L 2 ∥/X1L 2 ⊥ → 0 (with L∥∙ L⊥ , the parallel and perpendicular diffusion length scales, respectively). Therefore, the approach is asymptotic-preserving. We demonstrate the capabilities of the scheme with several numerical experiments with varying magnetic field complexity in two dimensions, including the case of transport across a magnetic island.« less

A guide to the metabolic pathways and function of metabolites observed in human brain 1H magnetic resonance spectra.

PubMed

Rae, Caroline D

2014-01-01

The current knowledge of the normal biochemistry of compounds that give rise to resonances in human brain proton magnetic resonance spectra measureable at readily available field strengths (i.e. ≤3 T) is reviewed. Molecules covered include myo- and scyllo-inositol, glycerophospho- and phospho-choline and choline, creatine and phosphocreatine, N-acetylaspartate, N-acetylaspartylglutamate, glutamate, glutamine, γ-aminobutyrate, glucose, glutathione and lactate. The factors which influence changes in the levels of these compounds are discussed. As most proton resonances in the brain at low field are derived from a combination of moieties whose biochemistry is complex and interrelated, an understanding of the mechanisms underlying why these species change is crucial to meaningful interpretation of human brain spectra.

Design and building of new spin polarized Positron Annihilation Induced Auger Electron Spectrometer

NASA Astrophysics Data System (ADS)

Lim, Zheng Hui; Mishler, Michael; Joglekar, Prasad; Shastry, Karthik; Koymen, Ali; Sharma, Suresh; Weiss, Alexander

2014-03-01

We propose to develop a next generation high flux variable energy spin-polarized position beam facility for materials studies. This new system will have a higher efficiency than our current system, and it will also be the first in the world to combine spin polarization with a time of flight Positron Annihilation induced Auger Electron Spectroscopy (PAES). The spin polarized positrons are electromagnetically guided towards the sample with an axial magnetic field and perpendicular electric fields. These incident positrons get annihilated at the surface of the sample creating two gamma rays and auger electrons via Auger transitions. These signals are useful in characterizing material surface, surface magnetization, and energy sharing in valence band. This new spectrometer, which is currently under construction, will be a next generation positron system. NSF.

Application of Ampere’s law to a non-infinite wire and to a moving charge

NASA Astrophysics Data System (ADS)

Aledealat, K.; Duston, C. L.

2018-07-01

In this work we demonstrate how to apply Ampere’s law to a non-infinite wire that is a part of a complete circuit with a steady current. We show that this can be done by considering the magnetic field from the whole circuit, without having to directly introduce the displacement current. This example can be used to isolate and clarify students’ confusion about the application of Ampere’s law to a short wire. The second part of this work focuses on the application of Ampere’s law to a non-relativistic moving charge. It exposes the students to the Dirac delta function in a physical example and guides them to finding the magnetic field of a moving charge in a reasonable way.