Sample records for major system components

  1. Optical read/write memory system components

    NASA Technical Reports Server (NTRS)

    Kozma, A.

    1972-01-01

    The optical components of a breadboard holographic read/write memory system have been fabricated and the parameters specified of the major system components: (1) a laser system; (2) an x-y beam deflector; (3) a block data composer; (4) the read/write memory material; (5) an output detector array; and (6) the electronics to drive, synchronize, and control all system components. The objectives of the investigation were divided into three concurrent phases: (1) to supply and fabricate the major components according to the previously established specifications; (2) to prepare computer programs to simulate the entire holographic memory system so that a designer can balance the requirements on the various components; and (3) to conduct a development program to optimize the combined recording and reconstruction process of the high density holographic memory system.

  2. Automation of cutting and drilling of composite components

    NASA Technical Reports Server (NTRS)

    Warren, Charles W.

    1991-01-01

    The task was to develop a preliminary plan for an automated system for the cutting and drilling of advanced aerospace composite components. The goal was to automate the production of these components, but the technology developed can be readily extended to other systems. There is an excellent opportunity for developing a state of the art automated system for the cutting and drilling of large composite components at NASA-Marshall. Most of the major system components are in place: the robot, the water jet pump, and the off-line programming system. The drilling system and the part location system are the only major components that need to be developed. Also, another water jet nozzle and a small amount of high pressure plumbing need to be purchased from, and installed.

  3. Introduction. ERIC Processing Manual, Section I.

    ERIC Educational Resources Information Center

    Brandhorst, Ted, Ed.

    This document describes the major organizational components of the Educational Resources Information Center (ERIC) system, the interactions between those components, and the major products and services provided by those components. (WTB)

  4. 24 CFR 572.125 - Replacement reserves.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... drawn down under the Cash and Management Information System when specifically needed to assist a... prevent severe financial hardship to families caused by the failure of a major system or component of the... families; and (3) The condition and age of the properties and each of their major systems and components...

  5. A Conceptual Framework for Analysis of Communication in Rural Social Systems.

    ERIC Educational Resources Information Center

    Axinn, George H.

    This paper describes a five-component system with ten major internal linkages which may be used as a model for studying information flow in any rural agricultural social system. The major components are production, supply, marketing, research, and extension education. In addition, definitions are offered of the crucial variables affecting…

  6. Apollo experience report guidance and control systems: Primary guidance, navigation, and control system development

    NASA Technical Reports Server (NTRS)

    Holley, M. D.; Swingle, W. L.; Bachman, S. L.; Leblanc, C. J.; Howard, H. T.; Biggs, H. M.

    1976-01-01

    The primary guidance, navigation, and control systems for both the lunar module and the command module are described. Development of the Apollo primary guidance systems is traced from adaptation of the Polaris Mark II system through evolution from Block I to Block II configurations; the discussion includes design concepts used, test and qualification programs performed, and major problems encountered. The major subsystems (inertial, computer, and optical) are covered. Separate sections on the inertial components (gyroscopes and accelerometers) are presented because these components represent a major contribution to the success of the primary guidance, navigation, and control system.

  7. Apollo experience report: Development of the extravehicular mobility unit

    NASA Technical Reports Server (NTRS)

    Lutz, C. C.; Stutesman, H. L.; Carson, M. A.; Mcbarron, J. W., II

    1975-01-01

    The development and performance history of the Apollo extravehicular mobility unit and its major subsystems is described. The three major subsystems, the pressure garment assembly, the portable life-support system, and the oxygen purge system, are defined and described in detail as is the evolutionary process that culminated in each major subsystem component. Descriptions of ground-support equipment and the qualification testing process for component hardware are also presented.

  8. Utilization of non-conventional systems for conversion of biomass to food components: Potential for utilization of algae in engineered foods

    NASA Technical Reports Server (NTRS)

    Karel, M.; Kamarei, A. R.; Nakhost, Z.

    1985-01-01

    The major nutritional components of the green algae (Scenedesmus obliquus) grown in a Constant Cell density Apparatus were determined. Suitable methodology to prepare proteins from which three major undesirable components of these cells (i.e., cell walls, nucleic acids, and pigments) were either removed or substantially reduced was developed. Results showed that processing of green algae to protein isolate enhances its potential nutritional and organoleptic acceptability as a diet component in a Controlled Ecological Life Support System.

  9. Two-lattice models of trace element behavior: A response

    NASA Astrophysics Data System (ADS)

    Ellison, Adam J. G.; Hess, Paul C.

    1990-08-01

    Two-lattice melt components of Bottinga and Weill (1972), Nielsen and Drake (1979), and Nielsen (1985) are applied to major and trace element partitioning between coexisting immiscible liquids studied by RYERSON and Hess (1978) and Watson (1976). The results show that (1) the set of components most successful in one system is not necessarily portable to another system; (2) solution non-ideality within a sublattice severely limits applicability of two-lattice models; (3) rigorous application of two-lattice melt components may yield effective partition coefficients for major element components with no physical interpretation; and (4) the distinction between network-forming and network-modifying components in the sense of the two-lattice models is not clear cut. The algebraic description of two-lattice models is such that they will most successfully limit the compositional dependence of major and trace element solution behavior when the effective partition coefficient of the component of interest is essentially the same as the bulk partition coefficient of all other components within its sublattice.

  10. Elevations, Major Component Isometric, Propellant Flow Schematic, and External Tank ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Elevations, Major Component Isometric, Propellant Flow Schematic, and External Tank Connection to Shuttle Main Engines - Space Transportation System, Space Shuttle Main Engine, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  11. Hidden Dangers.

    ERIC Educational Resources Information Center

    Greven, Erik D. W.; Knox, Winthrop S.

    1999-01-01

    Discusses each of the major system components of a maintenance survey that can provide pool facilities with the information needed to properly maintain aging pools. Components examined include mechanical and structural systems; pool structure; and the filtration, circulation, and chemical treatment systems. (GR)

  12. Airborne trace contaminants of possible interest in CELSS

    NASA Technical Reports Server (NTRS)

    Garavelli, J. S.

    1986-01-01

    One design goal of Closed Ecological Life Support Systems (CELSS) for long duration space missions is to maintain an atmosphere which is healthy for all the desirable biological species and not deleterious to any of the mechanical components in that atmosphere. CELESS design must take into account the interactions of at least six major components; (1) humans and animals, (2) higher plants, (3) microalgae, (4) bacteria and fungi, (5) the waste processing system, and (6) other mechanical systems. Each of these major components can be both a source and a target of airborne trace contaminants in a CELSS. A range of possible airborne trace contaminants is discussed within a chemical classification scheme. These contaminants are analyzed with respect to their probable sources among the six major components and their potential effects on those components. Data on airborne chemical contaminants detected in shuttle missions is presented along with this analysis. The observed concentrations of several classes of compounds, including hydrocarbons, halocarbons, halosilanes, amines and nitrogen oxides, are considered with respect to the problems which they present to CELSS.

  13. LOX/hydrocarbon auxiliary propulsion system study

    NASA Technical Reports Server (NTRS)

    Orton, G. F.; Mark, T. D.; Weber, D. D.

    1982-01-01

    Liquid oxygen/hydrocarbon propulsion systems applicable to a second generation orbiter OMS/RCS were compared, and major system/component options were evaluated. A large number of propellant combinations and system concepts were evaluated. The ground rules were defined in terms of candidate propellants, system/component design options, and design requirements. System and engine component math models were incorporated into existing computer codes for system evaluations. The detailed system evaluations and comparisons were performed to identify the recommended propellant combination and system approach.

  14. Structural design principles for delivery of bioactive components in nutraceuticals and functional foods.

    PubMed

    McClements, David Julian; Decker, Eric Andrew; Park, Yeonhwa; Weiss, Jochen

    2009-06-01

    There have been major advances in the design and fabrication of structured delivery systems for the encapsulation of nutraceutical and functional food components. A wide variety of delivery systems is now available, each with its own advantages and disadvantages for particular applications. This review begins by discussing some of the major nutraceutical and functional food components that need to be delivered and highlights the main limitations to their current utilization within the food industry. It then discusses the principles underpinning the rational design of structured delivery systems: the structural characteristics of the building blocks; the nature of the forces holding these building blocks together; and, the different ways of assembling these building blocks into structured delivery systems. Finally, we review the major types of structured delivery systems that are currently available to food scientists: lipid-based (simple, multiple, multilayer, and solid lipid particle emulsions); surfactant-based (simple micelles, mixed micelles, vesicles, and microemulsions) and biopolymer-based (soluble complexes, coacervates, hydrogel droplets, and particles). For each type of delivery system we describe its preparation, properties, advantages, and limitations.

  15. Potential for utilization of algal biomass for components of the diet in CELSS

    NASA Technical Reports Server (NTRS)

    Kamarei, A. R.; Nakhost, Z.; Karel, M.

    1986-01-01

    The major nutritional components of the green algae (Scenedesmus obliquus) grown in a Constant Cell Density Apparatus were determined. Suitable methodology to prepare proteins from which three major undesirable components of these cells (i.e., cell walls, nucleic acids, and pigments) were either removed or substantially reduced was developed. Results showed that processing of green algae to protein isolate enhances is potential nutritional and organoleptic acceptability as a diet component in controlled Ecological Life Support System.

  16. Department of Defense Healthcare Management System Modernization (DHMSM)

    DTIC Science & Technology

    2016-03-01

    2016 Major Automated Information System Annual Report Department of Defense Healthcare Management System Modernization (DHMSM) Defense...DSN Fax: Date Assigned: November 16, 2015 Program Information Program Name Department of Defense Healthcare Management System Modernization...DHMSM) DoD Component DoD The acquiring DoD Component is Program Executive Office (PEO) Department of Defense (DoD) Healthcare Management Systems (DHMS

  17. Computer-Aided Modeling and Analysis of Power Processing Systems (CAMAPPS). Phase 1: Users handbook

    NASA Technical Reports Server (NTRS)

    Kim, S.; Lee, J.; Cho, B. H.; Lee, F. C.

    1986-01-01

    The EASY5 macro component models developed for the spacecraft power system simulation are described. A brief explanation about how to use the macro components with the EASY5 Standard Components to build a specific system is given through an example. The macro components are ordered according to the following functional group: converter power stage models, compensator models, current-feedback models, constant frequency control models, load models, solar array models, and shunt regulator models. Major equations, a circuit model, and a program listing are provided for each macro component.

  18. Multishaker modal testing

    NASA Technical Reports Server (NTRS)

    Craig, R. R., Jr.

    1985-01-01

    A component mode synthesis method for damped structures was developed and modal test methods were explored which could be employed to determine the relevant parameters required by the component mode synthesis method. Research was conducted on the following topics: (1) Development of a generalized time-domain component mode synthesis technique for damped systems; (2) Development of a frequency-domain component mode synthesis method for damped systems; and (3) Development of a system identification algorithm applicable to general damped systems. Abstracts are presented of the major publications which have been previously issued on these topics.

  19. Turbomachine Interface Sealing

    NASA Technical Reports Server (NTRS)

    Hendricks, Robert C.; Chupp, Raymond E.; Lattime, Scott B.; Steinetz, Bruce M.

    2005-01-01

    Sealing interfaces and coatings, like lubricants, are sacrificial, giving up their integrity for the benefit of the component. Clearance control is a major issue in power systems turbomachine design and operational life. Sealing becomes the most cost-effective way to enhance system performance. Coatings, films, and combined use of both metals and ceramics play a major role in maintaining interface clearances in turbomachine sealing and component life. This paper focuses on conventional and innovative materials and design practices for sealing interfaces.

  20. Water reuse systems: A review of the principal components

    USGS Publications Warehouse

    Lucchetti, G.; Gray, G.A.

    1988-01-01

    Principal components of water reuse systems include ammonia removal, disease control, temperature control, aeration, and particulate filtration. Effective ammonia removal techniques include air stripping, ion exchange, and biofiltration. Selection of a particular technique largely depends on site-specific requirements (e.g., space, existing water quality, and fish densities). Disease control, although often overlooked, is a major problem in reuse systems. Pathogens can be controlled most effectively with ultraviolet radiation, ozone, or chlorine. Simple and inexpensive methods are available to increase oxygen concentration and eliminate gas supersaturation, these include commercial aerators, air injectors, and packed columns. Temperature control is a major advantage of reuse systems, but the equipment required can be expensive, particularly if water temperature must be rigidly controlled and ambient air temperature fluctuates. Filtration can be readily accomplished with a hydrocyclone or sand filter that increases overall system efficiency. Based on criteria of adaptability, efficiency, and reasonable cost, we recommend components for a small water reuse system.

  1. Multimode fiber optic wavelength division multiplexing

    NASA Technical Reports Server (NTRS)

    Spencer, J. L.

    1982-01-01

    Optical wavelength division multiplexing (WDM) systems, with signals transmitted on different wavelengths through a single optical fiber, can have increased bandwidth and fault isolation properties over single wavelength optical systems. Two WDM system designs that might be used with multimode fibers are considered and a general description of the components which could be used to implement the system are given. The components described are sources, multiplexers, demultiplexers, and detectors. Emphasis is given to the demultiplexer technique which is the major developmental component in the WDM system.

  2. Online Oxide Contamination Measurement and Purification Demonstration

    NASA Technical Reports Server (NTRS)

    Bradley, D. E.; Godfroy, T. J.; Webster, K. L.; Garber, A. E.; Polzin, K. A.; Childers, D. J.

    2011-01-01

    Liquid metal sodium-potassium (NaK) has advantageous thermodynamic properties indicating its use as a fission reactor coolant for a surface (lunar, martian) power system. A major area of concern for fission reactor cooling systems is system corrosion due to oxygen contaminants at the high operating temperatures experienced. A small-scale, approximately 4-L capacity, simulated fission reactor cooling system employing NaK as a coolant was fabricated and tested with the goal of demonstrating a noninvasive oxygen detection and purification system. In order to generate prototypical conditions in the simulated cooling system, several system components were designed, fabricated, and tested. These major components were a fully-sealed, magnetically-coupled mechanical NaK pump, a graphite element heated reservoir, a plugging indicator system, and a cold trap. All system components were successfully demonstrated at a maximum system flow rate of approximately 150 cc/s at temperatures up to 550 C. Coolant purification was accomplished using a cold trap before and after plugging operations which showed a relative reduction in oxygen content.

  3. High bit rate convolutional channel encoder/decoder

    NASA Technical Reports Server (NTRS)

    1977-01-01

    A detailed description of the design approach and tradeoffs encountered during the development of the 50 MBPS decoder system is presented. A functional analysis of each of the major logical functions is given, and the system's major components are listed.

  4. Command and Service Module Communications

    NASA Technical Reports Server (NTRS)

    Interbartolo, Michael

    2009-01-01

    This viewgraph presentation examines Command and Service Module (CSM) Communications. The communication system's capabilities are defined, including CSM-Earth, CSM-Lunar Module and CSM-Extravehicular crewman communications. An overview is provided for S-band communications, including data transmission and receiving rates, operating frequencies and major system components (pre-modulation processors, unified S-band electronics, S-band power amplifier and S-band antennas). Additionally, data transmission rates, operating frequencies and the capabilities of VHF communications are described. Major VHF components, including transmitters and receivers, and the VHF multiplexer and antennas are also highlighted. Finally, communications during pre-launch, ascent, in-flight and entry are discussed. Overall, the CSM communication system was rated highly by flight controllers and crew. The system was mostly autonomous for both crew and flight controllers and no major issues were encountered during flight.

  5. Outline Guide to Educational Reform Initiatives. ERS Research Digest.

    ERIC Educational Resources Information Center

    Educational Research Service, Arlington, VA.

    Many educational reform initiatives are being tried in an effort to restructure the American school system. This guide compares major educational reform efforts by goal, vision, teaching and learning, and system components. The first section of the guide covers major systemic educational reform initiatives, including Accelerated Schools Project,…

  6. Costs and description of a solar-energy system--Austin, Texas

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Heating and cooling system uses Fresnel lens concentrating collectors. Major system components are 36 collectors, 1,500 gallon thermal storage tank, absorption cooler, cooling tower, heating coil, pumps, heat exchanger, and backup heating and air conditioning. Final report includes detailed breakdown of component and installation costs for seven project subsystems.

  7. Executive control systems in the engineering design environment. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Hurst, P. W.

    1985-01-01

    An executive control system (ECS) is a software structure for unifying various applications codes into a comprehensive system. It provides a library of applications, a uniform access method through a cental user interface, and a data management facility. A survey of twenty-four executive control systems designed to unify various CAD/CAE applications for use in diverse engineering design environments within government and industry was conducted. The goals of this research were to establish system requirements to survey state-of-the-art architectural design approaches, and to provide an overview of the historical evolution of these systems. Foundations for design are presented and include environmental settings, system requirements, major architectural components, and a system classification scheme based on knowledge of the supported engineering domain(s). An overview of the design approaches used in developing the major architectural components of an ECS is presented with examples taken from the surveyed systems. Attention is drawn to four major areas of ECS development: interdisciplinary usage; standardization; knowledge utilization; and computer science technology transfer.

  8. Shuttle cryogenic supply system optimization study

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Technical information on different cryogenic supply systems is presented for selecting representative designs. Parametric data and sensitivity studies, and an evaluation of related technology status are included. An integrated mathematical model for hardware program support was developed. The life support system, power generation, and propellant supply are considered. The major study conclusions are the following: Optimum integrated systems tend towards maximizing liquid storage. Vacuum jacketing of tanks is a major effect on integrated systems. Subcritical storage advantages over supercritical storage decrease as the quantity of propellant or reactant decreases. Shuttle duty cycles are not severe. The operational mode has a significant effect on reliability. Components are available for most subsystem applications. Subsystems and components require a minimum amount of technology development.

  9. The Numerical Propulsion System Simulation: An Overview

    NASA Technical Reports Server (NTRS)

    Lytle, John K.

    2000-01-01

    Advances in computational technology and in physics-based modeling are making large-scale, detailed simulations of complex systems possible within the design environment. For example, the integration of computing, communications, and aerodynamics has reduced the time required to analyze major propulsion system components from days and weeks to minutes and hours. This breakthrough has enabled the detailed simulation of major propulsion system components to become a routine part of designing systems, providing the designer with critical information about the components early in the design process. This paper describes the development of the numerical propulsion system simulation (NPSS), a modular and extensible framework for the integration of multicomponent and multidisciplinary analysis tools using geographically distributed resources such as computing platforms, data bases, and people. The analysis is currently focused on large-scale modeling of complete aircraft engines. This will provide the product developer with a "virtual wind tunnel" that will reduce the number of hardware builds and tests required during the development of advanced aerospace propulsion systems.

  10. State-of-the-art survey of multimode fiber optic wavelength division multiplexing

    NASA Astrophysics Data System (ADS)

    Spencer, J. L.

    1983-05-01

    Optical wavelength division multiplexing (WDM) systems, with signals transmitted on different wavelengths through a single fiber, can have increased information capacity and fault isolation properties over single wavelength optical systems. This paper describes a typical WDM system. Also, a state-of-the-art survey of optical multimode components which could be used to implement the system is made. The components to be surveyed are sources, multiplexers, and detectors. Emphasis is given to the demultiplexer techniques which are the major development components in the WDM system.

  11. Development and fabrication of a solar cell junction processing system

    NASA Technical Reports Server (NTRS)

    Kiesling, R.

    1981-01-01

    The major component fabrication program was completed. Assembly and system testing of the pulsed electron beam annealing machine are described. The design program for the transport reached completion, and the detailed drawings were released for fabrication and procurement of the long lead time components.

  12. 40 CFR 86.1824-08 - Durability demonstration procedures for evaporative emissions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... deterioration rate and emission level that effectively represents a significant majority of the distribution of... stabilize the permeability of all non-metallic fuel and evaporative system components to the mileage... permeability of evaporative and fuel system components. The manufacturer must also provide information...

  13. 40 CFR 86.1824-08 - Durability demonstration procedures for evaporative emissions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... deterioration rate and emission level that effectively represents a significant majority of the distribution of... stabilize the permeability of all non-metallic fuel and evaporative system components to the mileage... permeability of evaporative and fuel system components. The manufacturer must also provide information...

  14. 40 CFR 86.1824-08 - Durability demonstration procedures for evaporative emissions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... deterioration rate and emission level that effectively represents a significant majority of the distribution of... stabilize the permeability of all non-metallic fuel and evaporative system components to the mileage... permeability of evaporative and fuel system components. The manufacturer must also provide information...

  15. Component Database for the APS Upgrade

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Veseli, S.; Arnold, N. D.; Jarosz, D. P.

    The Advanced Photon Source Upgrade (APS-U) project will replace the existing APS storage ring with a multi-bend achromat (MBA) lattice to provide extreme transverse coherence and extreme brightness x-rays to its users. As the time to replace the existing storage ring accelerator is of critical concern, an aggressive one-year removal/installation/testing period is being planned. To aid in the management of the thousands of components to be installed in such a short time, the Component Database (CDB) application is being developed with the purpose to identify, document, track, locate, and organize components in a central database. Three major domains are beingmore » addressed: Component definitions (which together make up an exhaustive "Component Catalog"), Designs (groupings of components to create subsystems), and Component Instances (“Inventory”). Relationships between the major domains offer additional "system knowledge" to be captured that will be leveraged with future tools and applications. It is imperative to provide sub-system engineers with a functional application early in the machine design cycle. Topics discussed in this paper include the initial design and deployment of CDB, as well as future development plans.« less

  16. Profiles 1999 State Report. Oklahoma Educational Indicators Program.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Education, Oklahoma City. Office of Accountability.

    The Oklahoma Educational Indicators Program is a system developed under the Oklahoma Education Reform Act of 1990 to assess the performance of public schools and school systems. "Profiles 1999" consists of state, district, and school components. Each component divides the information presented into three major reporting categories: (1)…

  17. Solar thermal program summary. Volume 1: Overview, fiscal year 1988

    NASA Astrophysics Data System (ADS)

    1989-02-01

    The goal of the solar thermal program is to improve overall solar thermal systems performance and provide cost-effective energy options that are strategically secure and environmentally benign. Major research activities include energy collection technology, energy conversion technology, and systems and applications technology for both CR and DR systems. This research is being conducted through research laboratories in close coordination with the solar thermal industry, utilities companies, and universities. The Solar Thermal Technology Program is pursuing the development of critical components and subsystems for improved energy collection and conversion devices. This development follows two basic paths: for CR systems, critical components include stretched membrane heliostats, direct absorption receivers (DARs), and transport subsystems for molten salt heat transfer fluids. These components offer the potential for a significant reduction in system costs; and for DR systems, critical components include stretched membrane dishes, reflux receivers, and Stirling engines. These components will significantly increase system reliability and efficiency, which will reduce costs. The major thrust of the program is to provide electric power. However, there is an increasing interest in the use of concentrated solar energy for applications such as detoxifying hazardous wastes and developing high-value transportable fuels. These potential uses of highly concentrated solar energy still require additional experiments to prove concept feasibility. The program goal of economically competitive energy reduction from solar thermal systems is being cooperatively addressed by industry and government.

  18. Fiber optics for the future - wavelength division multiplexing

    NASA Technical Reports Server (NTRS)

    Spencer, J. L.

    1982-01-01

    Optical wavelength division multiplexing (WDM) systems, with signals transmitted on different wavelengths through a single fiber, can have increased information capacity and fault isolation properties over single wavelength optical systems. This paper describes a typical WDM system. The applicability of future standards to such a system are discussed. Also, a state-of-the-art survey of optical multimode components which could be used to implement the system are made. The components to be surveyed are sources, multiplexers, and detectors. Emphasis is given to the demultiplexer techniques which are the major developmental components in the WDM system.

  19. Energy Conversion Alternatives Study (ECAS), Westinghouse phase 1. Volume 10: Liquid-metal MHD systems. [energy conversion efficiency of electric power plants using liquid metal magnetohydrodynamics

    NASA Technical Reports Server (NTRS)

    Holman, R. R.; Lippert, T. E.

    1976-01-01

    Electric Power Plant costs and efficiencies are presented for two basic liquid-metal cycles corresponding to 922 and 1089 K (1200 and 1500 F) for a commercial applications using direct coal firing. Sixteen plant designs are considered for which major component equipment were sized and costed. The design basis for each major component is discussed. Also described is the overall systems computer model that was developed to analyze the thermodynamics of the various cycle configurations that were considered.

  20. Demonstration of fully coupled simplified extended station black-out accident simulation with RELAP-7

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhao, Haihua; Zhang, Hongbin; Zou, Ling

    2014-10-01

    The RELAP-7 code is the next generation nuclear reactor system safety analysis code being developed at the Idaho National Laboratory (INL). The RELAP-7 code develop-ment effort started in October of 2011 and by the end of the second development year, a number of physical components with simplified two phase flow capability have been de-veloped to support the simplified boiling water reactor (BWR) extended station blackout (SBO) analyses. The demonstration case includes the major components for the primary system of a BWR, as well as the safety system components for the safety relief valve (SRV), the reactor core isolation cooling (RCIC)more » system, and the wet well. Three scenar-ios for the SBO simulations have been considered. Since RELAP-7 is not a severe acci-dent analysis code, the simulation stops when fuel clad temperature reaches damage point. Scenario I represents an extreme station blackout accident without any external cooling and cooling water injection. The system pressure is controlled by automatically releasing steam through SRVs. Scenario II includes the RCIC system but without SRV. The RCIC system is fully coupled with the reactor primary system and all the major components are dynamically simulated. The third scenario includes both the RCIC system and the SRV to provide a more realistic simulation. This paper will describe the major models and dis-cuss the results for the three scenarios. The RELAP-7 simulations for the three simplified SBO scenarios show the importance of dynamically simulating the SRVs, the RCIC sys-tem, and the wet well system to the reactor safety during extended SBO accidents.« less

  1. The design of components for an advanced Rankine cycle test facility.

    NASA Technical Reports Server (NTRS)

    Bond, J. A.

    1972-01-01

    The design of a facility for testing components of an advanced Rankine cycle power system is summarized. The facility is a three-loop system in which lithium, potassium and NaK-78 are the working fluids of the primary, secondary and heat-rejection loops, respectively. Design bases and performance predictions for the major loop components, including the lithium heater and the potassium boiler, condenser and preheater, are outlined.

  2. Preparation of monotectic alloys having a controlled microstructure by directional solidification under dopant-induced interface breakdown

    NASA Technical Reports Server (NTRS)

    Parr, R. A.; Johnston, M. H.; Mcclure, J. C.

    1980-01-01

    Monotectic alloys having aligned spherical particles of rods of the minor component dispersed in a matrix of the major component are prepared by forming a melt containing predetermined amounts of the major and minor components of a chosen monotectic system, providing in the melt a dopant capable of breaking down the liquid solid interface for the chosen alloy, and directionally solidfying the melt at a selected temperature gradient and a selected rate of movement of the liquid-solid interface (growth rate). Shaping of the minor component into spheres or rods and the spacing between them are controlled by the amount of dopant and the temperature gradient and growth rate values. Specific alloy systems include Al Bi, Al Pb and Zn Bi, using a transition element such as iron.

  3. 10 CFR 52.79 - Contents of applications; technical information in final safety analysis report.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... assurance program will be implemented; (26) The applicant's organizational structure, allocations or... presents a safety analysis of the structures, systems, and components of the facility as a whole. The final... contain an analysis and evaluation of the major structures, systems, and components of the facility that...

  4. 10 CFR 52.157 - Contents of applications; technical information in final safety analysis report.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... analysis of the structures, systems, and components of the reactor to be manufactured, with emphasis upon... assumed for this evaluation should be based upon a major accident, hypothesized for purposes of site... structures, systems, and components with the objective of assessing the risk to public health and safety...

  5. A System for Sentiment Analysis of Colloquial Arabic Using Human Computation

    PubMed Central

    Al-Subaihin, Afnan S.; Al-Khalifa, Hend S.

    2014-01-01

    We present the implementation and evaluation of a sentiment analysis system that is conducted over Arabic text with evaluative content. Our system is broken into two different components. The first component is a game that enables users to annotate large corpuses of text in a fun manner. The game produces necessary linguistic resources that will be used by the second component which is the sentimental analyzer. Two different algorithms have been designed to employ these linguistic resources to analyze text and classify it according to its sentimental polarity. The first approach is using sentimental tag patterns, which reached a precision level of 56.14%. The second approach is the sentimental majority approach which relies on calculating the number of negative and positive phrases in the sentence and classifying the sentence according to the dominant polarity. The results after evaluating the system for the first sentimental majority approach yielded the highest accuracy level reached by our system which is 60.5% while the second variation scored an accuracy of 60.32%. PMID:24892064

  6. FTIR gas chromatographic analysis of perfumes

    NASA Astrophysics Data System (ADS)

    Diederich, H.; Stout, Phillip J.; Hill, Stephen L.; Krishnan, K.

    1992-03-01

    Perfumes, natural or synthetic, are complex mixtures consisting of numerous components. Gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) techniques have been extensively utilized for the analysis of perfumes and essential oils. A limited number of perfume samples have also been analyzed by FT-IR gas chromatographic (GC-FTIR) techniques. Most of the latter studies have been performed using the conventional light pipe (LP) based GC-FTIR systems. In recent years, cold-trapping (in a matrix or neat) GC-FTIR systems have become available. The cold-trapping systems are capable of sub-nanogram sensitivities. In this paper, comparison data between the LP and the neat cold-trapping GC- FTIR systems is presented. The neat cold-trapping interface is known as Tracer. The results of GC-FTIR analysis of some commercial perfumes is also presented. For comparison of LP and Tracer GC-FTIR systems, a reference (synthetic) mixture containing 16 major and numerous minor constituents was used. The components of the mixture are the compounds commonly encountered in commercial perfumes. The GC-FTIR spectra of the reference mixture was obtained under identical chromatographic conditions from an LP and a Tracer system. A comparison of the two sets of data thus generated do indeed show the enhanced sensitivity level of the Tracer system. The comparison also shows that some of the major components detected by the Tracer system were absent from the LP data. Closer examination reveals that these compounds undergo thermal decomposition on contact with the hot gold surface that is part of the LP system. GC-FTIR data were obtained for three commercial perfume samples. The major components of these samples could easily be identified by spectra search against a digitized spectral library created using the Tracer data from the reference mixture.

  7. Essential Oil of Aristolochia trilobata: Synthesis, Routes of Exposure, Acute Toxicity, Binary Mixtures and Behavioral Effects on Leaf-Cutting Ants.

    PubMed

    de Oliveira, Bruna Maria S; Melo, Carlisson R; Alves, Péricles B; Santos, Abraão A; Santos, Ane Caroline C; Santana, Alisson da S; Araújo, Ana Paula A; Nascimento, Pedro E S; Blank, Arie F; Bacci, Leandro

    2017-02-25

    Plants of the genus Aristolochia have been frequently reported as important medicinal plants. Despite their high bioactive potential, to date, there are no reports of their effects on leaf-cutting ants. Therefore, the present study aimed to evaluate the insecticidal activity of the essential oil of Aristolochia trilobata and its major components on Atta sexdens and Acromyrmex balzani , two species of leaf-cutting ants. The bioassays were performed regarding routes of exposure, acute toxicity, binary mixtures of the major components and behavioral effects. Twenty-five components were identified in the essential oil of A. trilobata using a gas chromatographic system equipped with a mass spectrometer and a flame ionization detector. The components found in higher proportions were sulcatyl acetate, limonene, p -cymene and linalool. The essential oil of A. trilobata and its individual major components were efficient against A. balzani and A. sexdens workers when applied by fumigation. These components showed fast and efficient insecticidal activity on ants. The components acted synergistically and additively on A. balzani and A. sexdens , respectively, and caused a strong repellency/irritability in the ants. Thus, our results demonstrate the great potential of the essential oil of A. trilobata and its major components for the development of new insecticides.

  8. Modeling of power electronic systems with EMTP

    NASA Technical Reports Server (NTRS)

    Tam, Kwa-Sur; Dravid, Narayan V.

    1989-01-01

    In view of the potential impact of power electronics on power systems, there is need for a computer modeling/analysis tool to perform simulation studies on power systems with power electronic components as well as to educate engineering students about such systems. The modeling of the major power electronic components of the NASA Space Station Freedom Electric Power System is described along with ElectroMagnetic Transients Program (EMTP) and it is demonstrated that EMTP can serve as a very useful tool for teaching, design, analysis, and research in the area of power systems with power electronic components. EMTP modeling of power electronic circuits is described and simulation results are presented.

  9. A UML-based ontology for describing hospital information system architectures.

    PubMed

    Winter, A; Brigl, B; Wendt, T

    2001-01-01

    To control the heterogeneity inherent to hospital information systems the information management needs appropriate hospital information systems modeling methods or techniques. This paper shows that, for several reasons, available modeling approaches are not able to answer relevant questions of information management. To overcome this major deficiency we offer an UML-based ontology for describing hospital information systems architectures. This ontology views at three layers: the domain layer, the logical tool layer, and the physical tool layer, and defines the relevant components. The relations between these components, especially between components of different layers make the answering of our information management questions possible.

  10. Workshop on the Space Environment: The Effects on the Optical Properties of Airless Bodies

    NASA Technical Reports Server (NTRS)

    Hapke, B. (Editor); Clark, B. (Editor); Benedix, G. (Editor); Domingue, D. (Editor); Cintala, M. (Editor)

    1993-01-01

    Reflectance spectrophotometry and polarimetry are major tools in remote sensing studies of surfaces of solar system bodies. The interpretations of such measurements are often based on laboratory studies of meteoritic, lunar, and terrestrial materials. However, the optical properties of regoliths are known to be affected by the space environment. Thus, some of the major questions addressed in the workshop include identity of the soil component responsible for alteration of the optical properties, the process that produced this component, and how reliably the effects of these processes could be extrapolated to other bodies of the solar system.

  11. Sensitivity analysis by approximation formulas - Illustrative examples. [reliability analysis of six-component architectures

    NASA Technical Reports Server (NTRS)

    White, A. L.

    1983-01-01

    This paper examines the reliability of three architectures for six components. For each architecture, the probabilities of the failure states are given by algebraic formulas involving the component fault rate, the system recovery rate, and the operating time. The dominant failure modes are identified, and the change in reliability is considered with respect to changes in fault rate, recovery rate, and operating time. The major conclusions concern the influence of system architecture on failure modes and parameter requirements. Without this knowledge, a system designer may pick an inappropriate structure.

  12. MOEMs, key optical components for future astronomical instrumentation in space

    NASA Astrophysics Data System (ADS)

    Zamkotsian, Frédéric; Dohlen, Kjetil; Burgarella, Denis; Ferrari, Marc; Buat, Veronique

    2017-11-01

    Based on the micro-electronics fabrication process, MicroOpto-Electro-Mechanical Systems (MOEMS) are under study, in order to be integrated in next-generation astronomical instruments and telescopes, especially for space missions. The main advantages of micro-optical components are their compactness, scalability, specific task customization using elementary building blocks, and they allows remote control. As these systems are easily replicable, the price of the components is decreasing dramatically when their number is increasing. The two major applications of MOEMS are Multi-Object Spectroscopy masks and Deformable Mirror systems.

  13. Revision, uptake and coding issues related to the open access Orchard Sports Injury Classification System (OSICS) versions 8, 9 and 10.1

    PubMed Central

    Orchard, John; Rae, Katherine; Brooks, John; Hägglund, Martin; Til, Lluis; Wales, David; Wood, Tim

    2010-01-01

    The Orchard Sports Injury Classification System (OSICS) is one of the world’s most commonly used systems for coding injury diagnoses in sports injury surveillance systems. Its major strengths are that it has wide usage, has codes specific to sports medicine and that it is free to use. Literature searches and stakeholder consultations were made to assess the uptake of OSICS and to develop new versions. OSICS was commonly used in the sports of football (soccer), Australian football, rugby union, cricket and tennis. It is referenced in international papers in three sports and used in four commercially available computerised injury management systems. Suggested injury categories for the major sports are presented. New versions OSICS 9 (three digit codes) and OSICS 10.1 (four digit codes) are presented. OSICS is a potentially helpful component of a comprehensive sports injury surveillance system, but many other components are required. Choices made in developing these components should ideally be agreed upon by groups of researchers in consensus statements. PMID:24198559

  14. Energy efficient engine component development and integration program

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Accomplishments in the Energy Efficient Engine Component Development and Integration program during the period of April 1, 1981 through September 30, 1981 are discussed. The major topics considered are: (1) propulsion system analysis, design, and integration; (2) engine component analysis, design, and development; (3) core engine tests; and (4) integrated core/low spool testing.

  15. Interaction between xanthan gum and cationic cellulose JR400 in aqueous solution.

    PubMed

    Li, Haiping; Hou, Wanguo; Li, Xiuzhi

    2012-06-05

    The electrostatic and hydrogen bonding interactions between xanthan gum (XG) and semisynthetic cationic cellulose (JR400) in aqueous solution are investigated via stability map, FT-IR spectra, thermogravimetric analysis, potentiometric measurement and rheological method. The stability map shows three regions, a stable region with XG as the major component, a flocculated region and another stable region with JR400 as the major component. The stability of mixing system depends on both the concentration fraction of JR400 (fJR) and the overlapping concentrations of these two polymers. In the region near the stoichiometric fJR, the mixture shows stoichiometric flocculation, which is independent of the total polymer concentration. However, in the regions away from the stoichiometric fJR, the mixtures are stable when the concentration of major polymer component is higher than its overlapping concentration. In stable regions, the electrostatic and hydrogen bonding interactions can enhance the viscosity of mixing system at appropriate fJR values. Copyright © 2012 Elsevier Ltd. All rights reserved.

  16. Component-Based Modelling for Scalable Smart City Systems Interoperability: A Case Study on Integrating Energy Demand Response Systems.

    PubMed

    Palomar, Esther; Chen, Xiaohong; Liu, Zhiming; Maharjan, Sabita; Bowen, Jonathan

    2016-10-28

    Smart city systems embrace major challenges associated with climate change, energy efficiency, mobility and future services by embedding the virtual space into a complex cyber-physical system. Those systems are constantly evolving and scaling up, involving a wide range of integration among users, devices, utilities, public services and also policies. Modelling such complex dynamic systems' architectures has always been essential for the development and application of techniques/tools to support design and deployment of integration of new components, as well as for the analysis, verification, simulation and testing to ensure trustworthiness. This article reports on the definition and implementation of a scalable component-based architecture that supports a cooperative energy demand response (DR) system coordinating energy usage between neighbouring households. The proposed architecture, called refinement of Cyber-Physical Component Systems (rCPCS), which extends the refinement calculus for component and object system (rCOS) modelling method, is implemented using Eclipse Extensible Coordination Tools (ECT), i.e., Reo coordination language. With rCPCS implementation in Reo, we specify the communication, synchronisation and co-operation amongst the heterogeneous components of the system assuring, by design scalability and the interoperability, correctness of component cooperation.

  17. Microterminal/Microfiche System for Computer-Based Instruction: Hardware and Software Development.

    DTIC Science & Technology

    1980-10-01

    Circuit Description and Schematic of Adaptor Module 57 Appendix C Circuit Description The schematics for circuitry used in the microfiche viewer and the...composed of four major components and associated interfaces. The major components are (a) mirroterminal. (Is) microfiche reader. (0) memory module , and (d...sensing of the position of the platen containing the microfiche so that frame locations can be verified by the microterminal software. The memory module is

  18. One Approach for Transitioning the iNET Standards into the IRIG 106 Telemetry Standards

    DTIC Science & Technology

    2015-05-26

    Protocol Suite. Figure 1 illustrates the Open Systems Interconnection ( OSI ) Model, the corresponding TCP/IP Model, and the major components of the TCP...IP Protocol Suite. Figure 2 represents the iNET-specific protocols layered onto the TCP/IP Model. Figure 1. OSI and TCP/IP Model with TCP/IP...Protocol Suite TCP/IP Protocol Suite Major Components IPv4 IPv6 TCP/IP Model OSI Model Application Presentation

  19. The Numerical Propulsion System Simulation: A Multidisciplinary Design System for Aerospace Vehicles

    NASA Technical Reports Server (NTRS)

    Lytle, John K.

    1999-01-01

    Advances in computational technology and in physics-based modeling are making large scale, detailed simulations of complex systems possible within the design environment. For example, the integration of computing, communications, and aerodynamics has reduced the time required to analyze ma or propulsion system components from days and weeks to minutes and hours. This breakthrough has enabled the detailed simulation of major propulsion system components to become a routine part of design process and to provide the designer with critical information about the components early in the design process. This paper describes the development of the Numerical Propulsion System Simulation (NPSS), a multidisciplinary system of analysis tools that is focussed on extending the simulation capability from components to the full system. This will provide the product developer with a "virtual wind tunnel" that will reduce the number of hardware builds and tests required during the development of advanced aerospace propulsion systems.

  20. Sequential Events Control System (SECS) Overview

    NASA Technical Reports Server (NTRS)

    Interbartolo, Michael

    2009-01-01

    This slide presentation will cover the Sequential Events Control System (SECS), which is the Apollo spacecraft subsystem that controls the automatically sequenced functions during the mission and during any a borts that could be performed. Included in this presentation are its general architecture, its integration into and use of the spacecraft' s other systems, and details on the functions it is responsible for c ontrolling during the mission. The objectives are to describe the system's architecture, the major components in the system, and the major system functions.

  1. Isotope Brayton electric power system for the 500 to 2500 watt range

    NASA Technical Reports Server (NTRS)

    Macosko, R. P.; Barna, G. J.; Block, H. B.; Ingle, B. D.

    1972-01-01

    An extensive study was conducted at the Lewis Research Center to evaluate an isotope Brayton electric power system for use in the 500 to 2500 W power range. Overall system simplicity was emphasized in order to reduce parasitic power losses and improve system reliability. Detailed parametric cycle analysis, conceptual component designs, and evaluation of system packaging were included. A single-loop system (gas) with six major components including one rotating unit was selected. Calculated net system efficiency varies from 23 to 28 percent over the power range.

  2. Concept for a Differential Lock and Traction Control Model in Automobiles

    NASA Astrophysics Data System (ADS)

    Shukul, A. K.; Hansra, S. K.

    2014-01-01

    The automobile is a complex integration of electronics and mechanical components. One of the major components is the differential which is limited due to its shortcomings. The paper proposes a concept of a cost effective differential lock and traction for passenger cars to sports utility vehicles alike, employing a parallel braking mechanism coming into action based on the relative speeds of the wheels driven by the differential. The paper highlights the employment of minimum number of components unlike the already existing systems. The system was designed numerically for the traction control and differential lock for the world's cheapest car. The paper manages to come up with all the system parameters and component costing making it a cost effective system.

  3. Component-Based Modelling for Scalable Smart City Systems Interoperability: A Case Study on Integrating Energy Demand Response Systems

    PubMed Central

    Palomar, Esther; Chen, Xiaohong; Liu, Zhiming; Maharjan, Sabita; Bowen, Jonathan

    2016-01-01

    Smart city systems embrace major challenges associated with climate change, energy efficiency, mobility and future services by embedding the virtual space into a complex cyber-physical system. Those systems are constantly evolving and scaling up, involving a wide range of integration among users, devices, utilities, public services and also policies. Modelling such complex dynamic systems’ architectures has always been essential for the development and application of techniques/tools to support design and deployment of integration of new components, as well as for the analysis, verification, simulation and testing to ensure trustworthiness. This article reports on the definition and implementation of a scalable component-based architecture that supports a cooperative energy demand response (DR) system coordinating energy usage between neighbouring households. The proposed architecture, called refinement of Cyber-Physical Component Systems (rCPCS), which extends the refinement calculus for component and object system (rCOS) modelling method, is implemented using Eclipse Extensible Coordination Tools (ECT), i.e., Reo coordination language. With rCPCS implementation in Reo, we specify the communication, synchronisation and co-operation amongst the heterogeneous components of the system assuring, by design scalability and the interoperability, correctness of component cooperation. PMID:27801829

  4. Resolution and identification of the protein components of the photosystem II antenna system of higher plants by reversed-phase liquid chromatography with electrospray-mass spectrometric detection.

    PubMed

    Corradini, D; Huber, C G; Timperio, A M; Zolla, L

    2000-07-21

    Reversed-phase liquid chromatography (RPLC) was interfaced to mass spectrometry (MS) with an electrospray ion (ESI) source for the separation and accurate molecular mass determination of the individual intrinsic membrane proteins that comprise the photosystem II (PS II) major light-harvesting complex (LHC II) and minor (CP24, CP26 and CP29) antenna system, whose molecular masses range between 22,000 and 29,000. PS II is a supramolecular complex intrinsic of the thylacoid membrane, which plays the important role in photosynthesis of capturing solar energy, and transferring it to photochemical reaction centers where energy conversion occurs. The protein components of the PS II major and minor antenna systems were extracted from spinach thylacoid membranes and separated using a butyl-silica column eluted by an acetonitrile gradient in 0.05% (v/v) aqueous trifluoroacetic acid. On-line electrospray MS allowed accurate molecular mass determination and identification of the protein components of PS II major and minor antenna system. The proposed RPLC-ESI-MS method holds several advantages over sodium dodecyl sulfate-polyacrylamide gel electrophoresis, the conventional technique for studying membrane proteins, including a better protein separation, mass accuracy, speed and efficiency.

  5. Component-Based Visualization System

    NASA Technical Reports Server (NTRS)

    Delgado, Francisco

    2005-01-01

    A software system has been developed that gives engineers and operations personnel with no "formal" programming expertise, but who are familiar with the Microsoft Windows operating system, the ability to create visualization displays to monitor the health and performance of aircraft/spacecraft. This software system is currently supporting the X38 V201 spacecraft component/system testing and is intended to give users the ability to create, test, deploy, and certify their subsystem displays in a fraction of the time that it would take to do so using previous software and programming methods. Within the visualization system there are three major components: the developer, the deployer, and the widget set. The developer is a blank canvas with widget menu items that give users the ability to easily create displays. The deployer is an application that allows for the deployment of the displays created using the developer application. The deployer has additional functionality that the developer does not have, such as printing of displays, screen captures to files, windowing of displays, and also serves as the interface into the documentation archive and help system. The third major component is the widget set. The widgets are the visual representation of the items that will make up the display (i.e., meters, dials, buttons, numerical indicators, string indicators, and the like). This software was developed using Visual C++ and uses COTS (commercial off-the-shelf) software where possible.

  6. The EMS system and disaster planning: some observations.

    PubMed

    Holloway, R D; Steliga, J F; Ryan, C T

    1978-02-01

    Disaster planning, one of the 15 essential components of the Emergency Medical Service System Act of 1973, should be the culmination of the establishment of other components. Regions have gone to varying lengths to describe disaster plans but how realistic the plans are is questionable. New York has planned for multiple casualty incidents (MCI) to care for victims of fires, explosions, structural collapses and major transportation incidents. The irrational emotional response in mass disasters conflicts with the rational disaster plans written by health planners. Drills of disaster plans are not realistic. One solution is to designate the next serious incident, such as a fire or traffic accident, a major MCI. The ability to handle an MCI is probably the best measure of an EMS system's effectiveness.

  7. The NASA-Lewis/ERDA Solar Heating and Cooling Technology Program

    NASA Technical Reports Server (NTRS)

    Couch, J. P.; Bloomfield, H. S.

    1975-01-01

    The NASA Lewis Research Center plans to carry out a major role in the ERDA Solar Heating and Cooling Program. This role would be to create and test the enabling technology for future solar heating, cooling, and combined heating/cooling systems. The major objectives of the project are to achieve reduction in solar energy system costs, while maintaining adequate performance, reliability, life, and maintenance characteristics. The project approach is to move progressively through component, subsystem, and then system technology advancement phases in parallel with continuing manufacturing cost assessment studies. This approach will be accomplished principally by contract with industry to develop advanced components and subsystems. This advanced hardware will be tested to establish 'technology readiness' both under controlled laboratory conditions and under real sun conditions.

  8. Integrated Evaluation of Closed Loop Air Revitalization System Components

    NASA Technical Reports Server (NTRS)

    Murdock, K.

    2010-01-01

    NASA s vision and mission statements include an emphasis on human exploration of space, which requires environmental control and life support technologies. This Contractor Report (CR) describes the development and evaluation of an Air Revitalization System, modeling and simulation of the components, and integrated hardware testing with the goal of better understanding the inherent capabilities and limitations of this closed loop system. Major components integrated and tested included a 4-Bed Modular Sieve, Mechanical Compressor Engineering Development Unit, Temperature Swing Adsorption Compressor, and a Sabatier Engineering and Development Unit. The requisite methodolgy and technical results are contained in this CR.

  9. Closed-cycle gas dynamic laser design investigation

    NASA Technical Reports Server (NTRS)

    Ketch, G. W.; Young, W. E.

    1977-01-01

    A conceptual design study was made of a closed cycle gas-dynamic laser to provide definition of the major components in the laser loop. The system potential application is for long range power transmission by way of high power laser beams to provide satellite propulsion energy for orbit changing or station keeping. A parametric cycle optimization was conducted to establish the thermodynamic requirements for the system components. A conceptual design was conducted of the closed cycle system and the individual components to define physical characteristics and establish the system size and weight. Technology confirmation experimental demonstration programs were outlined to develop, evaluate, and demonstrate the technology base needed for this closed cycle GDL system.

  10. Space micro-guidance and control - Applications and architectures

    NASA Technical Reports Server (NTRS)

    Mettler, Edward; Hadaegh, Fred Y.

    1992-01-01

    The features and the components of a new microscale guidance, navigation, and control (GN&C) system for future space systems are discussed. An approach is described for the utilization of new microengineering technologies for achieving major reductions in the GN&C system's mass, size, power, and costs. The micro-GN&C system and the component concepts include microactuated adaptive optics, micromachined inertial sensors, fiberoptic data nets with light-power transmission, and VLSI microcomputers. The GN&C system will be applied in microspacecraft, microlanders, microrovers, remote sensing platforms, interferometers, and deployable reflectors.

  11. Space micro-guidance and control - Applications and architectures

    NASA Astrophysics Data System (ADS)

    Mettler, Edward; Hadaegh, Fred Y.

    1992-07-01

    The features and the components of a new microscale guidance, navigation, and control (GN&C) system for future space systems are discussed. An approach is described for the utilization of new microengineering technologies for achieving major reductions in the GN&C system's mass, size, power, and costs. The micro-GN&C system and the component concepts include microactuated adaptive optics, micromachined inertial sensors, fiberoptic data nets with light-power transmission, and VLSI microcomputers. The GN&C system will be applied in microspacecraft, microlanders, microrovers, remote sensing platforms, interferometers, and deployable reflectors.

  12. Displays and simulators

    NASA Astrophysics Data System (ADS)

    Mohon, N.

    A 'simulator' is defined as a machine which imitates the behavior of a real system in a very precise manner. The major components of a simulator and their interaction are outlined in brief form, taking into account the major components of an aircraft flight simulator. Particular attention is given to the visual display portion of the simulator, the basic components of the display, their interactions, and their characteristics. Real image displays are considered along with virtual image displays, and image generators. Attention is given to an advanced simulator for pilot training, a holographic pancake window, a scan laser image generator, the construction of an infrared target simulator, and the Apollo Command Module Simulator.

  13. Multidisciplinary propulsion simulation using the numerical propulsion system simulator (NPSS)

    NASA Technical Reports Server (NTRS)

    Claus, Russel W.

    1994-01-01

    Implementing new technology in aerospace propulsion systems is becoming prohibitively expensive. One of the major contributions to the high cost is the need to perform many large scale system tests. The traditional design analysis procedure decomposes the engine into isolated components and focuses attention on each single physical discipline (e.g., fluid for structural dynamics). Consequently, the interactions that naturally occur between components and disciplines can be masked by the limited interactions that occur between individuals or teams doing the design and must be uncovered during expensive engine testing. This overview will discuss a cooperative effort of NASA, industry, and universities to integrate disciplines, components, and high performance computing into a Numerical propulsion System Simulator (NPSS).

  14. Integration Test of the High Voltage Hall Accelerator System Components

    NASA Technical Reports Server (NTRS)

    Kamhawi, Hani; Haag, Thomas; Huang, Wensheng; Pinero, Luis; Peterson, Todd; Dankanich, John

    2013-01-01

    NASA Glenn Research Center is developing a 4 kilowatt-class Hall propulsion system for implementation in NASA science missions. NASA science mission performance analysis was completed using the latest high voltage Hall accelerator (HiVHAc) and Aerojet-Rocketdyne's state-of-the-art BPT-4000 Hall thruster performance curves. Mission analysis results indicated that the HiVHAc thruster out performs the BPT-4000 thruster for all but one of the missions studied. Tests of the HiVHAc system major components were performed. Performance evaluation of the HiVHAc thruster at NASA Glenn's vacuum facility 5 indicated that thruster performance was lower than performance levels attained during tests in vacuum facility 12 due to the lower background pressures attained during vacuum facility 5 tests when compared to vacuum facility 12. Voltage-Current characterization of the HiVHAc thruster in vacuum facility 5 showed that the HiVHAc thruster can operate stably for a wide range of anode flow rates for discharge voltages between 250 and 600 volts. A Colorado Power Electronics enhanced brassboard power processing unit was tested in vacuum for 1,500 hours and the unit demonstrated discharge module efficiency of 96.3% at 3.9 kilowatts and 650 volts. Stand-alone open and closed loop tests of a VACCO TRL 6 xenon flow control module were also performed. An integrated test of the HiVHAc thruster, brassboard power processing unit, and xenon flow control module was performed and confirmed that integrated operation of the HiVHAc system major components. Future plans include continuing the maturation of the HiVHAc system major components and the performance of a single-string integration test.

  15. Software For Graphical Representation Of A Network

    NASA Technical Reports Server (NTRS)

    Mcallister, R. William; Mclellan, James P.

    1993-01-01

    System Visualization Tool (SVT) computer program developed to provide systems engineers with means of graphically representing networks. Generates diagrams illustrating structures and states of networks defined by users. Provides systems engineers powerful tool simplifing analysis of requirements and testing and maintenance of complex software-controlled systems. Employs visual models supporting analysis of chronological sequences of requirements, simulation data, and related software functions. Applied to pneumatic, hydraulic, and propellant-distribution networks. Used to define and view arbitrary configurations of such major hardware components of system as propellant tanks, valves, propellant lines, and engines. Also graphically displays status of each component. Advantage of SVT: utilizes visual cues to represent configuration of each component within network. Written in Turbo Pascal(R), version 5.0.

  16. 14 CFR 125.287 - Initial and recurrent pilot testing requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., instrument approach facilities and procedures; (5) Air traffic control procedures, including IFR procedures... certificate holder; (2) For each type of airplane to be flown by the pilot, the airplane powerplant, major components and systems, major appliances, performance and operating limitations, standard and emergency...

  17. Quality and Safety in Health Care, Part XII: The Work System, Testing, and Clinical Reasoning.

    PubMed

    Harolds, Jay A

    2016-07-01

    Donabedian felt the 3 major components affecting quality were process, structure, and outcome. Later investigators often substitute the word "structure" for a broader concept called the "work system." One component of the latter is the people involved, and for diagnosis, this often is best done with a diagnostic team. The work system in diagnosis has many obstacles to achieve optimum performance. There are also important problems with how tests are ordered and interpreted and clinical reasoning and biases.

  18. Working on reform. How workers' compensation medical care is affected by health care reform.

    PubMed

    Himmelstein, J; Rest, K

    1996-01-01

    The medical component of workers' compensation programs-now costing over $24 billion annually-and the rest of the nation's medical care system are linked. They share the same patients and providers. They provide similar benefits and services. And they struggle over who should pay for what. Clearly, health care reform and restructuring will have a major impact on the operation and expenditures of the workers' compensation system. For a brief period, during the 1994 national health care reform debate, these two systems were part of the same federal policy development and legislative process. With comprehensive health care reform no longer on the horizon, states now are tackling both workers' compensation and medical system reforms on their own. This paper reviews the major issues federal and state policy makers face as they consider reforms affecting the relationship between workers' compensation and traditional health insurance. What is the relationship of the workers' compensation cost crisis to that in general health care? What strategies are being considered by states involved in reforming the medical component of workers compensation? What are the major policy implications of these strategies?

  19. Design challenges in nanoparticle-based platforms: Implications for targeted drug delivery systems

    NASA Astrophysics Data System (ADS)

    Mullen, Douglas Gurnett

    Characterization and control of heterogeneous distributions of nanoparticle-ligand components are major design challenges for nanoparticle-based platforms. This dissertation begins with an examination of poly(amidoamine) (PAMAM) dendrimer-based targeted delivery platform. A folic acid targeted modular platform was developed to target human epithelial cancer cells. Although active targeting was observed in vitro, active targeting was not found in vivo using a mouse tumor model. A major flaw of this platform design was that it did not provide for characterization or control of the component distribution. Motivated by the problems experienced with the modular design, the actual composition of nanoparticle-ligand distributions were examined using a model dendrimer-ligand system. High Pressure Liquid Chromatography (HPLC) resolved the distribution of components in samples with mean ligand/dendrimer ratios ranging from 0.4 to 13. A peak fitting analysis enabled the quantification of the component distribution. Quantified distributions were found to be significantly more heterogeneous than commonly expected and standard analytical parameters, namely the mean ligand/nanoparticle ratio, failed to adequately represent the component heterogeneity. The distribution of components was also found to be sensitive to particle modifications that preceded the ligand conjugation. With the knowledge gained from this detailed distribution analysis, a new platform design was developed to provide a system with dramatically improved control over the number of components and with improved batch reproducibility. Using semi-preparative HPLC, individual dendrimer-ligand components were isolated. The isolated dendrimer with precise numbers of ligands were characterized by NMR and analytical HPLC. In total, nine different dendrimer-ligand components were obtained with degrees of purity ≥80%. This system has the potential to serve as a platform to which a precise number of functional molecules can be attached and has the potential to dramatically improve platform efficacy. An additional investigation of reproducibility challenges for current dendrimer-based platform designs is also described. The mass transport quality during the partial acetylation reaction of the dendrimer was found to have a major impact on subsequent dendrimer-ligand distributions that cannot be detected by standard analytical techniques. Consequently, this reaction should be eliminated from the platform design. Finally, optimized protocols for purification and characterization of PAMAM dendrimer were detailed.

  20. 76 FR 21393 - Agency Information Collection Activities: Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ... startup cost components or annual operation, maintenance, and purchase of service components. You should describe the methods you use to estimate major cost factors, including system and technology acquisition.... Capital and startup costs include, among other items, computers and software you purchase to prepare for...

  1. 76 FR 25367 - Agency Information Collection Activities: Proposed Collection, Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-04

    ... startup cost components or annual operation, maintenance, and purchase of service components. You should describe the methods you use to estimate major cost factors, including system and technology acquisition.... Capital and startup costs include, among other items, computers and software you purchase to prepare for...

  2. The Program Evaluation Guide: A Preliminary Review of Special Education Instruction

    ERIC Educational Resources Information Center

    Nulty, Elizabeth C.

    2017-01-01

    Special education programs vary in the quality of services provided across states, cities, and school districts. There are three major components necessary for a quality special education program for children with complex learning needs. These components include systems level analysis, capacity building for staff, and strong individual student…

  3. 48 CFR 227.7103-13 - Government right to review, verify, challenge and validate asserted restrictions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... contracting officer shall not challenge a contractor's assertion that a commercial item, component, or process... to development of the item, component or process. (2) Presumption regarding development exclusively... validation of asserted restrictions for technical data related to commercial items, and to major systems, on...

  4. 48 CFR 227.7103-13 - Government right to review, verify, challenge and validate asserted restrictions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... contracting officer shall not challenge a contractor's assertion that a commercial item, component, or process... to development of the item, component or process. (2) Presumption regarding development exclusively... validation of asserted restrictions for technical data related to commercial items, and to major systems, on...

  5. 48 CFR 227.7103-13 - Government right to review, verify, challenge and validate asserted restrictions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... contracting officer shall not challenge a contractor's assertion that a commercial item, component, or process... to development of the item, component or process. (2) Presumption regarding development exclusively... validation of asserted restrictions for technical data related to commercial items, and to major systems, on...

  6. 48 CFR 227.7103-13 - Government right to review, verify, challenge and validate asserted restrictions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... contracting officer shall not challenge a contractor's assertion that a commercial item, component, or process... to development of the item, component or process. (2) Presumption regarding development exclusively... validation of asserted restrictions for technical data related to commercial items, and to major systems, on...

  7. Neuropharmacological effects of Nigella sativa

    PubMed Central

    Beheshti, Farimah; Khazaei, Majid; Hosseini, Mahmoud

    2016-01-01

    Nigella sativa (NS) (Ranunculaceae family) is generally utilized as a therapeutic plant all over the world. The seeds of the plant have a long history of use in different frameworks of medicines and food. In Islamic literature, it is considered as one of the greatest forms of therapeutics. It has been widely used to treat nervous system diseases such as memory impairment, epilepsy, neurotoxicity, pain, etc. Additionally, this is uncovered that the majority of therapeutic properties of this plant are due to the presence of thymoquinone (TQ) which is a major bioactive component of the essential oil. Pharmacological studies have been done to evaluate the effects of NS on the central nervous system (CNS). The present review is an effort to provide a detailed scientific literature survey about pharmacological activities of the plant on nervous system. Our literature review showed that NS and its components can be considered as promising agents in the treatment of nervous system disorders. PMID:27247928

  8. High performance VLSI telemetry data systems

    NASA Technical Reports Server (NTRS)

    Chesney, J.; Speciale, N.; Horner, W.; Sabia, S.

    1990-01-01

    NASA's deployment of major space complexes such as Space Station Freedom (SSF) and the Earth Observing System (EOS) will demand increased functionality and performance from ground based telemetry acquisition systems well above current system capabilities. Adaptation of space telemetry data transport and processing standards such as those specified by the Consultative Committee for Space Data Systems (CCSDS) standards and those required for commercial ground distribution of telemetry data, will drive these functional and performance requirements. In addition, budget limitations will force the requirement for higher modularity, flexibility, and interchangeability at lower cost in new ground telemetry data system elements. At NASA's Goddard Space Flight Center (GSFC), the design and development of generic ground telemetry data system elements, over the last five years, has resulted in significant solutions to these problems. This solution, referred to as the functional components approach includes both hardware and software components ready for end user application. The hardware functional components consist of modern data flow architectures utilizing Application Specific Integrated Circuits (ASIC's) developed specifically to support NASA's telemetry data systems needs and designed to meet a range of data rate requirements up to 300 Mbps. Real-time operating system software components support both embedded local software intelligence, and overall system control, status, processing, and interface requirements. These components, hardware and software, form the superstructure upon which project specific elements are added to complete a telemetry ground data system installation. This paper describes the functional components approach, some specific component examples, and a project example of the evolution from VLSI component, to basic board level functional component, to integrated telemetry data system.

  9. A geostationary satellite system for mobile multimedia applications using portable, aeronautical and mobile terminals

    NASA Technical Reports Server (NTRS)

    Losquadro, G.; Luglio, M.; Vatalaro, F.

    1997-01-01

    A geostationary satellite system for mobile multimedia services via portable, aeronautical and mobile terminals was developed within the framework of the Advanced Communications Technology Service (ACTS) programs. The architecture of the system developed under the 'satellite extremely high frequency communications for multimedia mobile services (SECOMS)/ACTS broadband aeronautical terminal experiment' (ABATE) project is presented. The system will be composed of a Ka band system component, and an extremely high frequency band component. The major characteristics of the space segment, the ground control station and the portable, aeronautical and mobile user terminals are outlined.

  10. Administrative Decision Making and Resource Allocation.

    ERIC Educational Resources Information Center

    Sardy, Susan; Sardy, Hyman

    This paper considers selected aspects of the systems analysis of administrative decisionmaking regarding resource allocations in an educational system. A model of the instructional materials purchase system is presented. The major components of this model are: environment, input, decision process, conversion structure, conversion process, output,…

  11. KENNEDY SPACE CENTER, FLA. - During power-up of the orbiter Discovery in the Orbiter Processing Facility, a technician moves a switch. Discovery has been undergoing Orbiter Major Modifications in the past year, ranging from wiring, control panels and black boxes to gaseous and fluid systems tubing and components. These systems were deserviced, disassembled, inspected, modified, reassembled, checked out and reserviced, as were most other systems onboard. The work includes the installation of the Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.”

    NASA Image and Video Library

    2003-08-27

    KENNEDY SPACE CENTER, FLA. - During power-up of the orbiter Discovery in the Orbiter Processing Facility, a technician moves a switch. Discovery has been undergoing Orbiter Major Modifications in the past year, ranging from wiring, control panels and black boxes to gaseous and fluid systems tubing and components. These systems were deserviced, disassembled, inspected, modified, reassembled, checked out and reserviced, as were most other systems onboard. The work includes the installation of the Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.”

  12. KENNEDY SPACE CENTER, FLA. - During power-up of the orbiter Discovery in the Orbiter Processing Facility, a technician turns on a switch. Discovery has been undergoing Orbiter Major Modifications in the past year, ranging from wiring, control panels and black boxes to gaseous and fluid systems tubing and components. These systems were deserviced, disassembled, inspected, modified, reassembled, checked out and reserviced, as were most other systems onboard. The work includes the installation of the Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.”

    NASA Image and Video Library

    2003-08-27

    KENNEDY SPACE CENTER, FLA. - During power-up of the orbiter Discovery in the Orbiter Processing Facility, a technician turns on a switch. Discovery has been undergoing Orbiter Major Modifications in the past year, ranging from wiring, control panels and black boxes to gaseous and fluid systems tubing and components. These systems were deserviced, disassembled, inspected, modified, reassembled, checked out and reserviced, as were most other systems onboard. The work includes the installation of the Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.”

  13. Simplified Phased-Mission System Analysis for Systems with Independent Component Repairs

    NASA Technical Reports Server (NTRS)

    Somani, Arun K.

    1996-01-01

    Accurate analysis of reliability of system requires that it accounts for all major variations in system's operation. Most reliability analyses assume that the system configuration, success criteria, and component behavior remain the same. However, multiple phases are natural. We present a new computationally efficient technique for analysis of phased-mission systems where the operational states of a system can be described by combinations of components states (such as fault trees or assertions). Moreover, individual components may be repaired, if failed, as part of system operation but repairs are independent of the system state. For repairable systems Markov analysis techniques are used but they suffer from state space explosion. That limits the size of system that can be analyzed and it is expensive in computation. We avoid the state space explosion. The phase algebra is used to account for the effects of variable configurations, repairs, and success criteria from phase to phase. Our technique yields exact (as opposed to approximate) results. We demonstrate our technique by means of several examples and present numerical results to show the effects of phases and repairs on the system reliability/availability.

  14. A fuselage/tank structure study for actively cooled hypersonic cruise vehicles: Active cooling system analysis

    NASA Technical Reports Server (NTRS)

    Stone, J. E.

    1975-01-01

    The effects of fuselage cross section and structural arrangement on the performance of actively cooled hypersonic cruise vehicles are investigated. An active cooling system which maintains the aircraft's entire surface area at temperatures below 394 K at Mach 6 is developed along with a hydrogen fuel tankage thermal protection system. Thermodynamic characteristics of the actively cooled thermal protection systems established are summarized. Design heat loads and coolant flowrate requirements are defined for each major structural section and for the total system. Cooling system weights are summarized at the major component level. Conclusions and recommendations are included.

  15. Analytical Formulation for Sizing and Estimating the Dimensions and Weight of Wind Turbine Hub and Drivetrain Components

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guo, Y.; Parsons, T.; King, R.

    This report summarizes the theory, verification, and validation of a new sizing tool for wind turbine drivetrain components, the Drivetrain Systems Engineering (DriveSE) tool. DriveSE calculates the dimensions and mass properties of the hub, main shaft, main bearing(s), gearbox, bedplate, transformer if up-tower, and yaw system. The level of fi¬ delity for each component varies depending on whether semiempirical parametric or physics-based models are used. The physics-based models have internal iteration schemes based on system constraints and design criteria. Every model is validated against available industry data or finite-element analysis. The verification and validation results show that the models reasonablymore » capture primary drivers for the sizing and design of major drivetrain components.« less

  16. Discovery Orbiter Major Modifications

    NASA Image and Video Library

    2003-08-27

    During power-up of the orbiter Discovery in the Orbiter Processing Facility, a technician moves a circuit reset on the cockpit console. Discovery has been undergoing Orbiter Major Modifications in the past year, ranging from wiring, control panels and black boxes to gaseous and fluid systems tubing and components. These systems were deserviced, disassembled, inspected, modified, reassembled, checked out and reserviced, as were most other systems onboard. The work includes the installation of the Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.”

  17. Antilock Braking Systems: Traffic Safety Tips

    DOT National Transportation Integrated Search

    1996-01-01

    This fact sheet, the NHTSA Facts: Summer 1996, defines antilock braking systems, and discusses their benefits, how they work, and their major components. It also details how one would get used to antilock brakes, discussing how they feel and operate ...

  18. The H1 detector at HERA

    NASA Astrophysics Data System (ADS)

    Abt, I.; Ahmed, T.; Aid, S.; Andreev, V.; Andrieu, B.; Appuhn, R. D.; Arnault, C.; Arpagaus, M.; Babaev, A.; Bärwolff, H.; Bán, J.; Banas, E.; Baranov, P.; Barrelet, E.; Bartel, W.; Barth, M.; Bassler, U.; Basti, F.; Baynham, D. E.; Baze, J.-M.; Beck, G. A.; Beck, H. P.; Bederede, D.; Behrend, H.-J.; Beigbeder, C.; Belousov, A.; Berger, Ch.; Bergstein, H.; Bernard, R.; Bernardi, G.; Bernet, R.; Bernier, R.; Berthon, U.; Bertrand-Coremans, G.; Besançon, M.; Beyer, R.; Biasci, J.-C.; Biddulph, P.; Bidoli, V.; Binder, E.; Binko, P.; Bizot, J.-C.; Blobel, V.; Blouzon, F.; Blume, H.; Borras, K.; Boudry, V.; Bourdarios, C.; Brasse, F.; Braunschweig, W.; Breton, D.; Brettel, H.; Brisson, V.; Bruncko, D.; Brune, C.; Buchner, U.; Büngener, L.; Bürger, J.; Büsser, F. W.; Buniatian, A.; Burke, S.; Burmeister, P.; Busata, A.; Buschhorn, G.; Campbell, A. J.; Carli, T.; Charles, F.; Charlet, M.; Chase, R.; Clarke, D.; Clegg, A. B.; Colombo, M.; Commichau, V.; Connolly, J. F.; Cornett, U.; Coughlan, J. A.; Courau, A.; Cousinou, M.-C.; Coutures, Ch.; Coville, A.; Cozzika, G.; Cragg, D. A.; Criegee, L.; Cronström, H. I.; Cunliffe, N. H.; Cvach, J.; Cyz, A.; Dagoret, S.; Dainton, J. B.; Danilov, M.; Dann, A. W. E.; Darvill, D.; Dau, W. D.; David, J.; David, M.; Day, R. J.; Deffur, E.; Delcourt, B.; Del Buono, L.; Descamps, F.; Devel, M.; Dewulf, J. P.; De Roeck, A.; Dingus, P.; Djidi, K.; Dollfus, C.; Dowell, J. D.; Dreis, H. B.; Drescher, A.; Dretzler, U.; Duboc, J.; Ducorps, A.; Düllmann, D.; Dünger, O.; Duhm, H.; Dulny, B.; Dupont, F.; Ebbinghaus, R.; Eberle, M.; Ebert, J.; Ebert, T. R.; Eckerlin, G.; Edwards, B. W. H.; Efremenko, V.; Egli, S.; Eichenberger, S.; Eichler, R.; Eisele, F.; Eisenhandler, E.; Ellis, N. N.; Ellison, R. J.; Elsen, E.; Epifantsev, A.; Erdmann, M.; Erdmann, W.; Ernst, G.; Evrard, E.; Falley, G.; Favart, L.; Fedotov, A.; Feeken, D.; Felst, R.; Feltesse, J.; Feng, Z. Y.; Fensome, I. F.; Fent, J.; Ferencei, J.; Ferrarotto, F.; Finke, K.; Flamm, K.; Flauger, W.; Fleischer, M.; Flieser, M.; Flower, P. S.; Flügge, G.; Fomenko, A.; Fominykh, B.; Forbush, M.; Formánek, J.; Foster, J. M.; Franke, G.; Fretwurst, E.; Fröchtenicht, W.; Fuhrmann, P.; Gabathuler, E.; Gabathuler, K.; Gadow, K.; Gamerdinger, K.; Garvey, J.; Gayler, J.; Gažo, E.; Gellrich, A.; Gennis, M.; Gensch, U.; Genzel, H.; Gerhards, R.; Geske, K.; Giesgen, I.; Gillespie, D.; Glasgow, W.; Godfrey, L.; Godlewski, J.; Goerlach, U.; Goerlich, L.; Gogitidze, N.; Goldberg, M.; Goodall, A. M.; Gorelov, I.; Goritchev, P.; Gosset, L.; Grab, C.; Grässler, H.; Grässler, R.; Greenshaw, T.; Gregory, C.; Greif, H.; Grewe, M.; Grindhammer, G.; Gruber, A.; Gruber, C.; Günther, S.; Haack, J.; Haguenauer, M.; Haidt, D.; Hajduk, L.; Hammer, D.; Hamon, O.; Hampel, M.; Handschuh, D.; Hangarter, K.; Hanlon, E. M.; Hapke, M.; Harder, U.; Harjes, J.; Hartz, P.; Hatton, P. E.; Haydar, R.; Haynes, W. J.; Heatherington, J.; Hedberg, V.; Hedgecock, C. R.; Heinzelmann, G.; Henderson, R. C. W.; Henschel, H.; Herma, R.; Herynek, I.; Hildesheim, W.; Hill, P.; Hill, D. L.; Hilton, C. D.; Hladký, J.; Hoeger, K. C.; Hopes, R. B.; Horisberger, R.; Hrisoho, A.; Huber, J.; Huet, Ph.; Hufnagel, H.; Huot, N.; Huppert, J.-F.; Ibbotson, M.; Imbault, D.; Itterbeck, H.; Jabiol, M.-A.; Jacholkowska, A.; Jacobsson, C.; Jaffré, M.; Jansen, T.; Jean, P.; Jeanjean, J.; Jönsson, L.; Johannsen, K.; Johnson, D. P.; Johnson, L.; Jovanovic, P.; Jung, H.; Kalmus, P. I. P.; Kant, D.; Kantel, G.; Karstensen, S.; Kasarian, S.; Kaschowitz, R.; Kasselmann, P.; Kathage, U.; Kaufmann, H. H.; Kemmerling, G.; Kenyon, I. R.; Kermiche, S.; Keuker, C.; Kiesling, C.; Klein, M.; Kleinwort, C.; Knies, G.; Ko, W.; Kobler, T.; Koch, J.; Köhler, T.; Köhne, J.; Kolander, M.; Kolanoski, H.; Kole, F.; Koll, J.; Kolya, S. D.; Koppitz, B.; Korbel, V.; Korn, M.; Kostka, P.; Kotelnikov, S. K.; Krasny, M. W.; Krehbiel, H.; Krivan, F.; Krücker, D.; Krüger, U.; Krüner-Marquis, U.; Kubantsev, M.; Kubenka, J. P.; Külper, T.; Küsel, H.-J.; Küster, H.; Kuhlen, M.; Kurča, T.; Kurzhöfer, J.; Kuznik, B.; Laforge, B.; Lamarche, F.; Lander, R.; Landon, M. P. J.; Lange, W.; Lange, W.; Langkau, R.; Lanius, P.; Laporte, J.-F.; Laptin, L.; Laskus, H.; Lebedev, A.; Lemler, M.; Lenhardt, U.; Leuschner, A.; Leverenz, C.; Levonian, S.; Lewin, D.; Ley, Ch.; Lindner, A.; Lindström, G.; Linsel, F.; Lipinski, J.; Liss, B.; Loch, P.; Lodge, A. B.; Lohmander, H.; Lopez, G. C.; Lottin, J.-P.; Lubimov, V.; Ludwig, K.; Lüers, D.; Lugetski, N.; Lundberg, B.; Maeshima, K.; Magnussen, N.; Malinovski, E.; Mani, S.; Marage, P.; Marks, J.; Marshall, R.; Martens, J.; Martin, F.; Martin, G.; Martin, R.; Martyn, H.-U.; Martyniak, J.; Masbender, V.; Masson, S.; Mavroidis, A.; Maxfield, S. J.; McMahon, S. J.; Mehta, A.; Meier, K.; Meissner, J.; Mercer, D.; Merz, T.; Meyer, C. A.; Meyer, H.; Meyer, J.; Mikocki, S.; Mills, J. L.; Milone, V.; Möck, J.; Monnier, E.; Montés, B.; Moreau, F.; Moreels, J.; Morgan, B.; Morris, J. V.; Morton, J. M.; Müller, K.; Murín, P.; Murray, S. A.; Nagovizin, V.; Naroska, B.; Naumann, Th.; Nayman, P.; Nepeipivo, A.; Newman, P.; Newman-Coburn, D.; Newton, D.; Neyret, D.; Nguyen, H. K.; Niebergall, F.; Niebuhr, C.; Nisius, R.; Novák, T.; Nováková, H.; Nowak, G.; Noyes, G. W.; Nyberg, M.; Oberlack, H.; Obrock, U.; Olsson, J. E.; Olszowska, J.; Orenstein, S.; Ould-Saada, F.; Pailler, P.; Palanque, S.; Panaro, E.; Panitch, A.; Parey, J.-Y.; Pascaud, C.; Patel, G. D.; Patoux, A.; Paulot, C.; Pein, U.; Peppel, E.; Perez, E.; Perrodo, P.; Perus, A.; Peters, S.; Pharabod, J.-P.; Phillips, H. T.; Phillips, J. P.; Pichler, Ch.; Pieuchot, A.; Pimpl, W.; Pitzl, D.; Porrovecchio, A.; Prell, S.; Prosi, R.; Quehl, H.; Rädel, G.; Raupach, F.; Rauschnabel, K.; Reboux, A.; Reimer, P.; Reinmuth, G.; Reinshagen, S.; Ribarics, P.; Riech, V.; Riedlberger, J.; Riege, H.; Riess, S.; Rietz, M.; Robertson, S. M.; Robmann, P.; Röpnack, P.; Roosen, R.; Rosenbauer, K.; Rostovtsev, A.; Royon, C.; Rudge, A.; Rüter, K.; Rudowicz, M.; Ruffer, M.; Rusakov, S.; Rusinov, V.; Rybicki, K.; Sacton, J.; Sahlmann, N.; Sanchez, E.; Sankey, D. P. C.; Savitski, M.; Schacht, P.; Schiek, S.; Schirm, N.; Schleif, S.; Schleper, P.; von Schlippe, W.; Schmidt, C.; Schmidt, D.; Schmidt, G.; Schmitz, W.; Schmücker, H.; Schröder, V.; Schütt, J.; Schuhmann, E.; Schulz, M.; Schwind, A.; Scobel, W.; Seehausen, U.; Sefkow, F.; Sell, R.; Seman, M.; Semenov, A.; Shatalov, P.; Shekelyan, V.; Sheviakov, I.; Shooshtari, H.; Shtarkov, L. N.; Siegmon, G.; Siewert, U.; Sirois, Y.; Sirous, A.; Skillicorn, I. O.; Škvařil, P.; Smirnov, P.; Smith, J. R.; Smolik, L.; Sole, D.; Soloviev, Y.; Špalek, J.; Spitzer, H.; von Staa, R.; Staeck, J.; Staroba, P.; Šťastný, J.; Steenbock, M.; Štefan, P.; Steffen, P.; Steinberg, R.; Steiner, H.; Stella, B.; Stephens, K.; Stier, J.; Stiewe, J.; Stösslein, U.; Strachota, J.; Straumann, U.; Strowbridge, A.; Struczinski, W.; Sutton, J. P.; Szkutnik, Z.; Tappern, G.; Tapprogge, S.; Taylor, R. E.; Tchernyshov, V.; Tchudakov, V.; Thiebaux, C.; Thiele, K.; Thompson, G.; Thompson, R. J.; Tichomirov, I.; Trenkel, C.; Tribanek, W.; Tröger, K.; Truöl, P.; Turiot, M.; Turnau, J.; Tutas, J.; Urban, L.; Urban, M.; Usik, A.; Valkár, Š.; Valkárová, A.; Vallée, C.; Van Beek, G.; Vanderkelen, M.; Van Lancker, L.; Van Mechelen, P.; Vartapetian, A.; Vazdik, Y.; Vecko, M.; Verrecchia, P.; Vick, R.; Villet, G.; Vogel, E.; Wacker, K.; Wagener, M.; Walker, I. W.; Walther, A.; Weber, G.; Wegener, D.; Wegner, A.; Weissbach, P.; Wellisch, H. P.; West, L.; White, D.; Willard, S.; Winde, M.; Winter, G.-G.; Wolff, Th.; Womersley, L. A.; Wright, A. E.; Wünsch, E.; Wulff, N.; Wyborn, B. E.; Yiou, T. P.; Žáček, J.; Zarbock, D.; Závada, P.; Zeitnitz, C.; Zhang, Z.; Ziaeepour, H.; Zimmer, M.; Zimmermann, W.; Zomer, F.; Zuber, K.; H1 Collaboration

    1997-02-01

    General aspects of the H1 detector at the electron-proton storage ring HERA as well as technical descriptions of the magnet, luminosity system, trigger, slow-control, data acquisition and off-line data handling are given. The three major components of the detector, the tracking, calorimeter and muon detectors, will be described in a forthcoming article. The present paper describes the detector that was used from 1992 to the end of 1994. After this a major upgrade of some components was undertaken. Some performance figures from luminosity runs at HERA during 1993 and 1994 are given.

  19. High temperature polymer concrete compositions

    DOEpatents

    Fontana, Jack J.; Reams, Walter

    1985-01-01

    This invention is concerned with a polymer concrete composition, which is a two-component composition useful with many bases including metal. Component A, the aggregate composition, is broadly composed of silica, silica flour, portland cement, and acrylamide, whereas Component B, which is primarily vinyl and acrylyl reactive monomers, is a liquid system. A preferred formulation emphasizing the major necessary components is as follows: ______________________________________ Component A: Silica sand 60-77 wt. % Silica flour 5-10 wt. % Portland cement 15-25 wt. % Acrylamide 1-5 wt. % Component B: Styrene 50-60 wt. % Trimethylolpropane 35-40 wt. % trimethacrylate ______________________________________ and necessary initiators, accelerators, and surfactants.

  20. The Maryland Refutation Proof Procedure.

    ERIC Educational Resources Information Center

    Minker, Jack; And Others

    The Maryland Refutation Proof Procedure System (MRPPS) is an interactive experimental system intended for studying deductive search methods. Although the work is oriented towards question-answering, MRPPS provides a general problem solving capability. There are three major components within MRPPS. These are: (1) an inference system, (2) a search…

  1. Deploying and operating integrated intelligent transportation systems : twenty questions and answers : guidance from the evaluation of the Metropolitan Model Deployment Initiative sites

    DOT National Transportation Integrated Search

    2000-01-01

    This report describes the results of a major data gathering effort aimed at tracking deployment of nine infrastructure components of the metropolitan ITS infrastructure in 78 of the largest metropolitan areas in the nation. The nine components are: F...

  2. A systems engineering analysis of three-point and four-point wind turbine drivetrain configurations

    DOE PAGES

    Guo, Yi; Parsons, Tyler; Dykes, Katherine; ...

    2016-08-24

    This study compares the impact of drivetrain configuration on the mass and capital cost of a series of wind turbines ranging from 1.5 MW to 5.0 MW power ratings for both land-based and offshore applications. The analysis is performed with a new physics-based drivetrain analysis and sizing tool, Drive Systems Engineering (DriveSE), which is part of the Wind-Plant Integrated System Design & Engineering Model. DriveSE uses physics-based relationships to size all major drivetrain components according to given rotor loads simulated based on International Electrotechnical Commission design load cases. The model's sensitivity to input loads that contain a high degree ofmore » variability was analyzed. Aeroelastic simulations are used to calculate the rotor forces and moments imposed on the drivetrain for each turbine design. DriveSE is then used to size all of the major drivetrain components for each turbine for both three-point and four-point configurations. The simulation results quantify the trade-offs in mass and component costs for the different configurations. On average, a 16.7% decrease in total nacelle mass can be achieved when using a three-point drivetrain configuration, resulting in a 3.5% reduction in turbine capital cost. This analysis is driven by extreme loads and does not consider fatigue. Thus, the effects of configuration choices on reliability and serviceability are not captured. Furthermore, a first order estimate of the sizing, dimensioning and costing of major drivetrain components are made which can be used in larger system studies which consider trade-offs between subsystems such as the rotor, drivetrain and tower.« less

  3. A systems engineering analysis of three-point and four-point wind turbine drivetrain configurations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guo, Yi; Parsons, Tyler; Dykes, Katherine

    This study compares the impact of drivetrain configuration on the mass and capital cost of a series of wind turbines ranging from 1.5 MW to 5.0 MW power ratings for both land-based and offshore applications. The analysis is performed with a new physics-based drivetrain analysis and sizing tool, Drive Systems Engineering (DriveSE), which is part of the Wind-Plant Integrated System Design & Engineering Model. DriveSE uses physics-based relationships to size all major drivetrain components according to given rotor loads simulated based on International Electrotechnical Commission design load cases. The model's sensitivity to input loads that contain a high degree ofmore » variability was analyzed. Aeroelastic simulations are used to calculate the rotor forces and moments imposed on the drivetrain for each turbine design. DriveSE is then used to size all of the major drivetrain components for each turbine for both three-point and four-point configurations. The simulation results quantify the trade-offs in mass and component costs for the different configurations. On average, a 16.7% decrease in total nacelle mass can be achieved when using a three-point drivetrain configuration, resulting in a 3.5% reduction in turbine capital cost. This analysis is driven by extreme loads and does not consider fatigue. Thus, the effects of configuration choices on reliability and serviceability are not captured. Furthermore, a first order estimate of the sizing, dimensioning and costing of major drivetrain components are made which can be used in larger system studies which consider trade-offs between subsystems such as the rotor, drivetrain and tower.« less

  4. Multiphysics Application Coupling Toolkit

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Campbell, Michael T.

    2013-12-02

    This particular consortium implementation of the software integration infrastructure will, in large part, refactor portions of the Rocstar multiphysics infrastructure. Development of this infrastructure originated at the University of Illinois DOE ASCI Center for Simulation of Advanced Rockets (CSAR) to support the center's massively parallel multiphysics simulation application, Rocstar, and has continued at IllinoisRocstar, a small company formed near the end of the University-based program. IllinoisRocstar is now licensing these new developments as free, open source, in hopes to help improve their own and others' access to infrastructure which can be readily utilized in developing coupled or composite software systems;more » with particular attention to more rapid production and utilization of multiphysics applications in the HPC environment. There are two major pieces to the consortium implementation, the Application Component Toolkit (ACT), and the Multiphysics Application Coupling Toolkit (MPACT). The current development focus is the ACT, which is (will be) the substrate for MPACT. The ACT itself is built up from the components described in the technical approach. In particular, the ACT has the following major components: 1.The Component Object Manager (COM): The COM package provides encapsulation of user applications, and their data. COM also provides the inter-component function call mechanism. 2.The System Integration Manager (SIM): The SIM package provides constructs and mechanisms for orchestrating composite systems of multiply integrated pieces.« less

  5. SEPAC flight software detailed design specifications, volume 1

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The detailed design specifications (as built) for the SEPAC Flight Software are defined. The design includes a description of the total software system and of each individual module within the system. The design specifications describe the decomposition of the software system into its major components. The system structure is expressed in the following forms: the control-flow hierarchy of the system, the data-flow structure of the system, the task hierarchy, the memory structure, and the software to hardware configuration mapping. The component design description includes details on the following elements: register conventions, module (subroutines) invocaton, module functions, interrupt servicing, data definitions, and database structure.

  6. Integration, design, and construction of a CELSS breadboard facility for bioregenerative life support system research

    NASA Technical Reports Server (NTRS)

    Prince, R.; Knott, W.; Buchanan, Paul

    1987-01-01

    Design criteria for the Biomass Production Chamber (BPC), preliminary operating procedures, and requirements for the future development of the Controlled Ecological Life Support System (CELSS) are discussed. CELSS, which uses a bioregenerative system, includes the following three major units: (1) a biomass production component to grow plants under controlled conditions; (2) food processing components to derive maximum edible content from all plant parts; and (3) waste management components to recover and recycle all solids, liquids, and gases necessary to support life. The current status of the CELSS breadboard facility is reviewed; a block diagram of a simplified version of CELSS and schematic diagrams of the BPS are included.

  7. Automotive Stirling Engine Mod 1 Design Review, volume 2

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The auxiliaries and the control system for the ASE MOD I: (1) provide the required fuel and air flows for a well controlled combustion process, generating heat to the Stirling cycle; (2) provide a driver acceptable method for controlling the power output of the engine; (3) provide adequate lubrication and cooling water circulation; (4) generate the electric energy required for engine and vehicle operation; (5) provide a driver acceptable method for starting, stopping and monitoring the engine; and (6) provide a guard system, that protects the engine at component or system malfunction. The control principles and the way the different components and sub-systems interact are described as well as the different auxiliaries, the air fuel system, the power control systems and the electronics. The arrangement and location of auxiliaries and other major components are also examined.

  8. Dual-Shaft Electric Propulsion (DSEP) Technology Development Program

    NASA Astrophysics Data System (ADS)

    1992-08-01

    The background, progress, and current state of the DOE-sponsored Advanced Dual-Shaft Electric Propulsion Technology Development are presented. Three electric-drive vehicles were build as conversions of a commercial gasoline-powered van, using program-designed components and systems as required. The vehicles were tested primarily on dynamometer or test tract. Component and system testing represented a major portion of the development effort. Test data are summarized in this report, and an Appendix contains the final component design specifications. This major programmatic concerns were the traction battery, the battery management system, the dc-to-ac inverter, the drive motor, the transaxle and its ancillary equipment, and the vehicle controller. Additional effort was devoted to vehicle-related equipment: gear selector, power steering, power brakes, accelerator, dashboard instrumentation, and heater. Design, development, and test activities are reported for each of these items, together with an appraisal (lessons learned) and recommendations for possible further work. Other programmatic results include a Cost and Commercialization Analysis, a Reliability and Hazards Analysis Study, Technical Recommendations for Next-Generation Development, and an assessment of overall program efforts.

  9. Solar heating and cooling demonstration project at Radian Corporation, Austin, Texas

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The solar heating and cooling system located at the Radian Corporation, Austin, Texas, is discussed. A technical description of the solar system is presented. The costs of the major components and the cost of installing the system are described. Flow diagrams and photographs of the solar system are provided.

  10. Space environmental effects on spacecraft: LEO materials selection guide, part 2

    NASA Astrophysics Data System (ADS)

    Silverman, Edward M.

    1995-08-01

    This document provides performance properties on major spacecraft materials and subsystems that have been exposed to the low-Earth orbit (LEO) space environment. Spacecraft materials include metals, polymers, composites, white and black paints, thermal-control blankets, adhesives, and lubricants. Spacecraft subsystems include optical components, solar cells, and electronics. Information has been compiled from LEO short-term spaceflight experiments (e.g., space shuttle) and from retrieved satellites of longer mission durations (e.g., Long Duration Exposure Facility). Major space environment effects include atomic oxygen (AO), ultraviolet radiation, micrometeoroids and debris, contamination, and particle radiation. The main objective of this document is to provide a decision tool to designers for designing spacecraft and structures. This document identifies the space environments that will affect the performance of materials and components, e.g., thermal-optical property changes of paints due to UV exposures, AO-induced surface erosion of composites, dimensional changes due to thermal cycling, vacuum-induced moisture outgassing, and surface optical changes due to AO/UV exposures. Where appropriate, relationships between the space environment and the attendant material/system effects are identified. Part 2 covers thermal control systems, power systems, optical components, electronic systems, and applications.

  11. Space environmental effects on spacecraft: LEO materials selection guide, part 2

    NASA Technical Reports Server (NTRS)

    Silverman, Edward M.

    1995-01-01

    This document provides performance properties on major spacecraft materials and subsystems that have been exposed to the low-Earth orbit (LEO) space environment. Spacecraft materials include metals, polymers, composites, white and black paints, thermal-control blankets, adhesives, and lubricants. Spacecraft subsystems include optical components, solar cells, and electronics. Information has been compiled from LEO short-term spaceflight experiments (e.g., space shuttle) and from retrieved satellites of longer mission durations (e.g., Long Duration Exposure Facility). Major space environment effects include atomic oxygen (AO), ultraviolet radiation, micrometeoroids and debris, contamination, and particle radiation. The main objective of this document is to provide a decision tool to designers for designing spacecraft and structures. This document identifies the space environments that will affect the performance of materials and components, e.g., thermal-optical property changes of paints due to UV exposures, AO-induced surface erosion of composites, dimensional changes due to thermal cycling, vacuum-induced moisture outgassing, and surface optical changes due to AO/UV exposures. Where appropriate, relationships between the space environment and the attendant material/system effects are identified. Part 2 covers thermal control systems, power systems, optical components, electronic systems, and applications.

  12. iSAW: Integrating Structure, Actors, and Water to study socio-hydro-ecological systems

    NASA Astrophysics Data System (ADS)

    Hale, Rebecca L.; Armstrong, Andrea; Baker, Michelle A.; Bedingfield, Sean; Betts, David; Buahin, Caleb; Buchert, Martin; Crowl, Todd; Dupont, R. Ryan; Ehleringer, James R.; Endter-Wada, Joanna; Flint, Courtney; Grant, Jacqualine; Hinners, Sarah; Horsburgh, Jeffery S.; Jackson-Smith, Douglas; Jones, Amber S.; Licon, Carlos; Null, Sarah E.; Odame, Augustina; Pataki, Diane E.; Rosenberg, David; Runburg, Madlyn; Stoker, Philip; Strong, Courtenay

    2015-03-01

    Urbanization, climate, and ecosystem change represent major challenges for managing water resources. Although water systems are complex, a need exists for a generalized representation of these systems to identify important components and linkages to guide scientific inquiry and aid water management. We developed an integrated Structure-Actor-Water framework (iSAW) to facilitate the understanding of and transitions to sustainable water systems. Our goal was to produce an interdisciplinary framework for water resources research that could address management challenges across scales (e.g., plot to region) and domains (e.g., water supply and quality, transitioning, and urban landscapes). The framework was designed to be generalizable across all human-environment systems, yet with sufficient detail and flexibility to be customized to specific cases. iSAW includes three major components: structure (natural, built, and social), actors (individual and organizational), and water (quality and quantity). Key linkages among these components include: (1) ecological/hydrologic processes, (2) ecosystem/geomorphic feedbacks, (3) planning, design, and policy, (4) perceptions, information, and experience, (5) resource access and risk, and (6) operational water use and management. We illustrate the flexibility and utility of the iSAW framework by applying it to two research and management problems: understanding urban water supply and demand in a changing climate and expanding use of green storm water infrastructure in a semi-arid environment. The applications demonstrate that a generalized conceptual model can identify important components and linkages in complex and diverse water systems and facilitate communication about those systems among researchers from diverse disciplines.

  13. Development of the Vibration Isolation System for the Advanced Resistive Exercise Device

    NASA Technical Reports Server (NTRS)

    Niebuhr, Jason H.; Hagen, Richard A.

    2011-01-01

    This paper describes the development of the Vibration Isolation System for the Advanced Resistive Exercise Device from conceptual design to lessons learned. Maintaining a micro-g environment on the International Space Station requires that experiment racks and major vibration sources be isolated. The challenge in characterizing exercise loads and testing the system in the presence of gravity led to a decision to qualify the system by analysis. Available data suggests that the system is successful in attenuating loads, yet there has been a major component failure and several procedural issues during its 3 years of operational use.

  14. Orbital transfer rocket engine technology 7.5K-LB thrust rocket engine preliminary design

    NASA Technical Reports Server (NTRS)

    Harmon, T. J.; Roschak, E.

    1993-01-01

    A preliminary design of an advanced LOX/LH2 expander cycle rocket engine producing 7,500 lbf thrust for Orbital Transfer vehicle missions was completed. Engine system, component and turbomachinery analysis at both on design and off design conditions were completed. The preliminary design analysis results showed engine requirements and performance goals were met. Computer models are described and model outputs are presented. Engine system assembly layouts, component layouts and valve and control system analysis are presented. Major design technologies were identified and remaining issues and concerns were listed.

  15. Louisville region demonstration of travel management coordination center : system pre-deployment preparation.

    DOT National Transportation Integrated Search

    2013-03-01

    The purpose of the Greater Louisville Region Demonstration of Travel Management Coordination Center (TMCC): System Pre-Deploy-ment Preparation grant was to further phased implementation of the regions TMCC design by focusing on two major component...

  16. Army Contract Writing System (ACWS)

    DTIC Science & Technology

    2016-03-01

    2016 Major Automated Information System Annual Report Army Contract Writing System (ACWS) Defense Acquisition Management Information Retrieval...Program Information Program Name Army Contract Writing System (ACWS) DoD Component Army Responsible Office Program Manager References MAIS...UNCLASSIFIED 4 Program Description The Army Contract Writing System (ACWS) will be the Army’s single, next-generation, enterprise-wide contract writing

  17. Prince Edward Island Newstarts' Comprehensive Manpower Development System.

    ERIC Educational Resources Information Center

    Connor, Thomas R.

    1971-01-01

    An approach to new methods of helping disadvantaged people gain employment taken by Prince Edward Island Newstart is outlined. This approach is a Comprehensive Manpower Development System. The major components of the system consist of: (1) variants of some standard manpower training programs, (2) innovative recruitment and assignment techniques,…

  18. 21 CFR 1020.30 - Diagnostic x-ray systems and their major components.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... Diagnostic x-ray system means an x-ray system designed for irradiation of any part of the human body for the... HUMAN SERVICES (CONTINUED) RADIOLOGICAL HEALTH PERFORMANCE STANDARDS FOR IONIZING RADIATION EMITTING... for the radiographic visualization and measurement of the dimensions of the human head. Coefficient of...

  19. 21 CFR 1020.30 - Diagnostic x-ray systems and their major components.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... Diagnostic x-ray system means an x-ray system designed for irradiation of any part of the human body for the... HUMAN SERVICES (CONTINUED) RADIOLOGICAL HEALTH PERFORMANCE STANDARDS FOR IONIZING RADIATION EMITTING... for the radiographic visualization and measurement of the dimensions of the human head. Coefficient of...

  20. Uses of GIS for Homeland Security and Emergency Management for Higher Education Institutions

    ERIC Educational Resources Information Center

    Murchison, Stuart B.

    2010-01-01

    Geographic information systems (GIS) are a major component of the geospatial sciences, which are also composed of geostatistical analysis, remote sensing, and global positional satellite systems. These systems can be integrated into GIS for georeferencing, pattern analysis, visualization, and understanding spatial concepts that transcend…

  1. A Five-Year Plan for Meeting the Automatic Data Processing and Telecommunications Needs of the Federal Government. Volume 2: Major Information Technology Systems Acquisition Plans of Federal Executive Agencies, 1984-1989.

    ERIC Educational Resources Information Center

    Department of Commerce, Washington, DC.

    This volume, the second of two, presents and analyzes the information technology acquisition plans of the Federal Government by agency and component. A brief description covers the outlays planned for major information technology acquisitions of general purpose data processing and telecommunications systems, facilities, and related services for 6…

  2. An automatic chip structure optical inspection system for electronic components

    NASA Astrophysics Data System (ADS)

    Song, Zhichao; Xue, Bindang; Liang, Jiyuan; Wang, Ke; Chen, Junzhang; Liu, Yunhe

    2018-01-01

    An automatic chip structure inspection system based on machine vision is presented to ensure the reliability of electronic components. It consists of four major modules, including a metallographic microscope, a Gigabit Ethernet high-resolution camera, a control system and a high performance computer. An auto-focusing technique is presented to solve the problem that the chip surface is not on the same focusing surface under the high magnification of the microscope. A panoramic high-resolution image stitching algorithm is adopted to deal with the contradiction between resolution and field of view, caused by different sizes of electronic components. In addition, we establish a database to storage and callback appropriate parameters to ensure the consistency of chip images of electronic components with the same model. We use image change detection technology to realize the detection of chip images of electronic components. The system can achieve high-resolution imaging for chips of electronic components with various sizes, and clearly imaging for the surface of chip with different horizontal and standardized imaging for ones with the same model, and can recognize chip defects.

  3. Assessment of district health system within inter-sectoral context in Nepal.

    PubMed

    Bhusal, C L; Singh, S P; Aryal, K K; Jha, B K; Ghimire, N; Shah, N; Khatiwada, D; Magar, A

    2013-05-01

    Inter-sectoral coordination has been one of the different factors in the district health system that produces efficient output which has been identified by the Alma Ata declaration as an essential component to achieve notion of 'Health for All'. This study was therefore aimed to describe the major four key functions of the health systems and to find out the situation of inter-sectoral coordination in Nepal. A mixed method with Focus Group Discussion (FGD) and In-Depth Interview with relevant personnel to collect the majority of the data was carried out from June 2012 to November 2012 from six districts selected purposively based on the health performance indicators. The major findings in relation to the key functions of district health systems showed that the overall management of the district health system happens under the leadership of chief of District Health Office of Public health office with the cooperation of all the personnel in different sections in a predetermined pattern and inter-sectoral coordination and collaboration exist only to a very limited extent. The major constraints for inter-sectoral coordination to be effective is lack of its planning and enforcement where inter-sectoral coordination could be important for both preventive and promotive health care, waste management, water supply and sanitation, health service utilization, pesticides and human health, agriculture and nutrition, air pollution. The main components in the district health system needs an immediate attention and inter-sectoral effort should be initiated from the central level and implemented in all the levels.

  4. EOSDIS: Archive and Distribution Systems in the Year 2000

    NASA Technical Reports Server (NTRS)

    Behnke, Jeanne; Lake, Alla

    2000-01-01

    Earth Science Enterprise (ESE) is a long-term NASA research mission to study the processes leading to global climate change. The Earth Observing System (EOS) is a NASA campaign of satellite observatories that are a major component of ESE. The EOS Data and Information System (EOSDIS) is another component of ESE that will provide the Earth science community with easy, affordable, and reliable access to Earth science data. EOSDIS is a distributed system, with major facilities at seven Distributed Active Archive Centers (DAACs) located throughout the United States. The EOSDIS software architecture is being designed to receive, process, and archive several terabytes of science data on a daily basis. Thousands of science users and perhaps several hundred thousands of non-science users are expected to access the system. The first major set of data to be archived in the EOSDIS is from Landsat-7. Another EOS satellite, Terra, was launched on December 18, 1999. With the Terra launch, the EOSDIS will be required to support approximately one terabyte of data into and out of the archives per day. Since EOS is a multi-mission program, including the launch of more satellites and many other missions, the role of the archive systems becomes larger and more critical. In 1995, at the fourth convening of NASA Mass Storage Systems and Technologies Conference, the development plans for the EOSDIS information system and archive were described. Five years later, many changes have occurred in the effort to field an operational system. It is interesting to reflect on some of the changes driving the archive technology and system development for EOSDIS. This paper principally describes the Data Server subsystem including how the other subsystems access the archive, the nature of the data repository, and the mass-storage I/O management. The paper reviews the system architecture (both hardware and software) of the basic components of the archive. It discusses the operations concept, code development, and testing phase of the system. Finally, it describes the future plans for the archive.

  5. Image guidance in orthopaedics and traumatology: A historical perspective.

    PubMed

    Székely, Gabor; Nolte, Lutz-P

    2016-10-01

    In this note we summarize the history of computer aided surgery in orthopaedics and traumatology from the end of the nineteenth century to currently observable future trends. We concentrate on the two major components of such systems, pre-operative planning and intra-operative execution. The evolution of the necessary technological components, the numerous platforms and components offered commercially as well as their clinical use are surveyed. Copyright © 2016. Published by Elsevier B.V.

  6. Saturn Apollo Program

    NASA Image and Video Library

    1967-01-01

    This cutaway illustration shows the Apollo Spacecraft with callouts of the major components. The spacecraft consisted of the lunar module, the service module, the command module, and the launch escape system.

  7. Photovoltaic power conditioning subsystem: State of the art and development opportunities

    NASA Technical Reports Server (NTRS)

    Krauthamer, S.; Bahrami, K.; Das, R.; Macie, T.; Rippel, W.

    1984-01-01

    Photovoltaic systems, the state of the art of power conditioning subsystem components, and the design and operational interaction between photovoltaic systems and host utilities are detailed in this document. Major technical issues relating to the design and development of power conditioning systems for photovoltaic application are considered; these include: (1) standards, guidelines, and specifications; (2) cost effective hardware design; (3) impact of advanced components on power conditioning development; (4) protection and safety; (5) quality of power; (6) system efficiency; and (7) system integration with the host utility. Theories of harmonic distortion and reactive power flow are discussed, and information about power conditioner hardware and manufacturers is provided.

  8. Isotope Brayton electric power system for the 500 to 2500 watt range.

    NASA Technical Reports Server (NTRS)

    Macosko, R. P.; Barna, G. J.; Block, H. B.; Ingle, B. D.

    1972-01-01

    An extensive study was conducted at the Lewis Research Center to evaluate an isotope Brayton electric power system for use in the 500 to 2500 W power range. The study emphasized overall system simplicity in order to reduce parasitic power losses and improve system reliability. The study included detailed parametric cycle analysis, conceptual component designs, and evaluation of system packaging. The study has resulted in the selection of a single-loop system (gas) with six major components including one rotating unit. Calculated net system efficiency varies from 23 to 28% over the power range. The use of the Pu-238 heat source being developed for the Multi-Hundred-Watt Radioisotope Thermoelectric Generator program was assumed.

  9. Data on Second Majors in Language and Literature, 2001-13

    ERIC Educational Resources Information Center

    Modern Language Association, 2015

    2015-01-01

    Data on second majors were added to the degree completions component of the United States Department of Education's Integrated Postsecondary Education Data System (IPEDS) in 2001 and were made available on the National Science Foundation's "WebCASPAR" Web site (https://webcaspar.nsf.gov/) in 2010. The Modern Language Association's first…

  10. Spaceborne sensors (1983-2000 AD): A forecast of technology

    NASA Technical Reports Server (NTRS)

    Kostiuk, T.; Clark, B. P.

    1984-01-01

    A technical review and forecast of space technology as it applies to spaceborne sensors for future NASA missions is presented. A format for categorization of sensor systems covering the entire electromagnetic spectrum, including particles and fields is developed. Major generic sensor systems are related to their subsystems, components, and to basic research and development. General supporting technologies such as cryogenics, optical design, and data processing electronics are addressed where appropriate. The dependence of many classes of instruments on common components, basic R&D and support technologies is also illustrated. A forecast of important system designs and instrument and component performance parameters is provided for the 1983-2000 AD time frame. Some insight into the scientific and applications capabilities and goals of the sensor systems is also given.

  11. 40 CFR 420.01 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... treatment system including schematic diagrams showing the major treatment system components and flow rates... request for consideration of alternative effluent limitations is to include: (i) A schematic diagram of... waters entering the treatment facility; discharge and recycle flow rates for each water source and each...

  12. 40 CFR 420.01 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... treatment system including schematic diagrams showing the major treatment system components and flow rates... request for consideration of alternative effluent limitations is to include: (i) A schematic diagram of... waters entering the treatment facility; discharge and recycle flow rates for each water source and each...

  13. 40 CFR 420.01 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... treatment system including schematic diagrams showing the major treatment system components and flow rates... request for consideration of alternative effluent limitations is to include: (i) A schematic diagram of... waters entering the treatment facility; discharge and recycle flow rates for each water source and each...

  14. 40 CFR 420.01 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... treatment system including schematic diagrams showing the major treatment system components and flow rates... request for consideration of alternative effluent limitations is to include: (i) A schematic diagram of... waters entering the treatment facility; discharge and recycle flow rates for each water source and each...

  15. Hybrid membrane--PSA system for separating oxygen from air

    DOEpatents

    Staiger, Chad L [Albuquerque, NM; Vaughn, Mark R [Albuquerque, NM; Miller, A Keith [Albuquerque, NM; Cornelius, Christopher J [Blackburg, VA

    2011-01-25

    A portable, non-cryogenic, oxygen generation system capable of delivering oxygen gas at purities greater than 98% and flow rates of 15 L/min or more is described. The system consists of two major components. The first component is a high efficiency membrane capable of separating argon and a portion of the nitrogen content from air, yielding an oxygen-enriched permeate flow. This is then fed to the second component, a pressure swing adsorption (PSA) unit utilizing a commercially available, but specifically formulated zeolite compound to remove the remainder of the nitrogen from the flow. The system is a unique gas separation system that can operate at ambient temperatures, for producing high purity oxygen for various applications (medical, refining, chemical production, enhanced combustion, fuel cells, etc . . . ) and represents a significant advance compared to current technologies.

  16. Space Qualification Issues in Acousto-optic and Electro-optic Devices

    NASA Technical Reports Server (NTRS)

    Prasad, Narasimha S.; Taylor, Edward W.; Trivedi, Sudhir; Kutcher, Sue; Soos, Jolanta

    2007-01-01

    Satellite and space-based applications of photonic devices and systems require operational reliability in the harsh environment of space for extended periods of time. This in turn requires every component of the systems and their packaging to meet space qualifications. Acousto- and electro-optical devices form the major components of many current space based optical systems, which is the focus of this paper. The major space qualification issues are related to: mechanical stability, thermal effects and operation of the devices in the naturally occurring space radiation environment. This paper will discuss acousto- and electro-optic materials and devices with respect to their stability against mechanical vibrations, thermal cycling in operating and non-operating conditions and device responses to space ionizing and displacement radiation effects. Selection of suitable materials and packaging to meet space qualification criteria will also be discussed. Finally, a general roadmap for production and testing of acousto- and electro-optic devices will be discussed.

  17. Rapid tooling for functional prototyping of metal mold processes. CRADA final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zacharia, T.; Ludtka, G.M.; Bjerke, M.A.

    1997-12-01

    The overall scope of this endeavor was to develop an integrated computer system, running on a network of heterogeneous computers, that would allow the rapid development of tool designs, and then use process models to determine whether the initial tooling would have characteristics which produce the prototype parts. The major thrust of this program for ORNL was the definition of the requirements for the development of the integrated die design system with the functional purpose to link part design, tool design, and component fabrication through a seamless software environment. The principal product would be a system control program that wouldmore » coordinate the various application programs and implement the data transfer so that any networked workstation would be useable. The overall system control architecture was to be required to easily facilitate any changes, upgrades, or replacements of the model from either the manufacturing end or the design criteria standpoint. The initial design of such a program is described in the section labeled ``Control Program Design``. A critical aspect of this research was the design of the system flow chart showing the exact system components and the data to be transferred. All of the major system components would have been configured to ensure data file compatibility and transferability across the Internet. The intent was to use commercially available packages to model the various manufacturing processes for creating the die and die inserts in addition to modeling the processes for which these parts were to be used. In order to meet all of these requirements, investigative research was conducted to determine the system flow features and software components within the various organizations contributing to this project. This research is summarized.« less

  18. Profiling study of the major and minor components of kaffir lime oil (Citrus hystrix DC.) in the fractional distillation process.

    PubMed

    Warsito, Warsito; Palungan, Maimunah Hindun; Utomo, Edy Priyo

    2017-01-01

    Essential oil is consisting of complex component. It is divided into major and minor component. Therefore, this study aims to examine the distribution of major and minor components on Kaffir lime oil by using fractional distillation. Fractional distillation and distributional analysis of components within fractions have been performed on kaffir lime oil ( Citrus hystrix DC .). Fractional distillation was performed by using PiloDist 104-VTU, column length of 2 m (number of plate 120), the system pressure was set on 5 and 10 mBar, while the reflux ratio varied on 10/10, 20/10 and 60/10, and the chemical composition analysis was done by using GC-MS. Chemical composition of the distillated lime oil consisted of mix-twigs and leaves that composed of 20 compounds, with five main components β-citronellal (46.40%), L-linalool (13.11%), β-citronellol (11.03%), citronelyl acetate (6.76%) and sabinen (5.91%). The optimum conditions for fractional distillation were obtained at 5 mBar pressure with reflux ratio of 10/10. Components of β -citronellal and L-linalool were distributed in the fraction-1 to fraction 9, hydrocarbon monoterpenes components were distributed only on the fraction-1 to fraction 4, while the oxygenated monoterpenes components dominated the fraction-5 to fraction-9. The highest level of β-citronellal was 84.86% (fraction-7), L-linalool 20.13% (fraction-5), sabinen 19.83% (fraction-1), and the component level of 4-terpeneol, β-citronellol and sitronelyl acetate respectively 7.16%; 12.27%; 5.22% (fraction-9).

  19. Performance Support Systems: Integrating AI, Hypermedia, and CBT to Enhance User Performance.

    ERIC Educational Resources Information Center

    McGraw, Karen L.

    1994-01-01

    Examines the use of a performance support system (PSS) to enhance user performance on an operational system. Highlights include background information that describes the stimulus for PSS development; discussion of the major PSS components and the technology they require; and discussion of the design of a PSS for a complex database system.…

  20. Vehicle for Space Transfer and Recovery (VSTAR), volume 2: Substantiating analyses and data

    NASA Technical Reports Server (NTRS)

    1988-01-01

    The Vehicle Space Transfer and Recovery (VSTAR) system is designed as a manned orbital transfer vehicle (MOTV) with the primary mission of Satellite Launch and Repair (SLR). Reference materials, calculations and trade studies used in the analysis and selection of VSTAR components. Each major VSTAR system is examined separately. Simple graphs and tables are used to make qualitative comparisons of various VSTAR component candidates. Equations and/or calculations used for a particular analysis are also included where applicable.

  1. Isolation and fractionation of soil humin using alkaline urea and dimethylsulphoxide plus sulphuric acid

    NASA Astrophysics Data System (ADS)

    Song, Guixue; Hayes, Michael H. B.; Novotny, Etelvino H.; Simpson, Andre J.

    2011-01-01

    Humin, the most recalcitrant and abundant organic fraction of soils and of sediments, is a significant contributor to the stable carbon pool in soils and is important for the global carbon budget. It has significant resistance to transformations by microorganisms. Based on the classical operational definition, humin can include any humic-type substance that is not soluble in water at any pH. We demonstrate in this study how sequential exhaustive extractions with 0.1 M sodium hydroxide (NaOH) + 6 M urea, followed by dimethylsulphoxide (DMSO) + 6% ( v/ v) sulphuric acid (H2SO4) solvent systems, can extract 70-80% of the residual materials remaining after prior exhaustive extractions in neutral and aqueous basic media. Solid-state 13C NMR spectra have shown that the components isolated in the base + urea system were compositionally similar to the humic and fulvic acid fractions isolated at pH 12.6 in the aqueous media. The NMR spectra indicated that the major components isolated in the DMSO + H2SO4 medium had aliphatic hydrocarbon associated with carboxyl functionalities and with lesser amounts of carbohydrate and peptide and minor amounts of lignin-derived components. The major components will have significant contributions from long-chain fatty acids, waxes, to cuticular materials. The isolates in the DMSO + H2SO4 medium were compositionally similar to the organic components that resisted solvation and remained associated with the soil clays. It is concluded that the base + urea system released humic and fulvic acids held by hydrogen bonding or by entrapment within the humin matrix. The recalcitrant humin materials extracted in DMSO + H2SO4 are largely biological molecules (from plants and the soil microbial population) that are likely to be protected from degradation by their hydrophobic moieties and by sorption on the soil clays. Thus, the major components of humin do not satisfy the classical definitions for humic substances which emphasise that these arise from microbial or chemical transformations in soils of the components of organic debris.

  2. A Systems Approach to the Physiology of Weightlessness

    NASA Technical Reports Server (NTRS)

    White, Ronald J.; Leonard, Joel I.; Rummel, John A.; Leach, Carolyn S.

    1991-01-01

    A systems approach to the unraveling of the complex response pattern of the human subjected to weightlessness is presented. The major goal of this research is to obtain an understanding of the role that each of the major components of the human system plays following the transition to and from space. The cornerstone of this approach is the utilization of a variety of mathematical models in order to pose and test alternative hypotheses concerned with the adaptation process. An integrated hypothesis for the human physiological response to weightlessness is developed.

  3. The Basis System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dubois, P.F.

    1989-05-16

    This paper discusses the basis system. Basis is a program development system for scientific programs. It has been developed over the last five years at Lawrence Livermore National Laboratory (LLNL), where it is now used in about twenty major programming efforts. The Basis System includes two major components, a program development system and a run-time package. The run-time package provides the Basis Language interpreter, through which the user does input, output, plotting, and control of the program's subroutines and functions. Variables in the scientific packages are known to this interpreter, so that the user may arbitrarily print, plot, and calculatemore » with, any major program variables. Also provided are facilities for dynamic memory management, terminal logs, error recovery, text-file i/o, and the attachment of non-Basis-developed packages.« less

  4. Interfaces - Weak Links, Yet Great Opportunities

    NASA Technical Reports Server (NTRS)

    Hendricks, Robert C.; Dimofte, Florin; Chupp, Raymond E.; Steinetz, Bruce M.

    2011-01-01

    Inadequate turbomachine interface design can rapidly degrade system performance, yet provide great opportunity for improvements. Engineered coatings of seals and bearing interfaces are major issues in the operational life of power systems. Coatings, films, and combined use of both metals and ceramics play a major role in maintaining component life. Interface coatings, like lubricants, are sacrificial for the benefit of the component. Bearing and sealing surfaces are routinely protected by tribologically paired coatings such as silicon diamond like coatings (SiDLC) in combination with an oil lubricated wave bearing that prolongs bearing operational life. Likewise, of several methods used or researched for detecting interface failures, dopants within coatings show failures in functionally graded ceramic coatings. The Bozzolo-Ferrante-Smith (BFS) materials models and quantum mechanical tools, employed in interface design, are discussed.

  5. Designing a Measurement Framework for Response to Intervention in Early Childhood Programs

    ERIC Educational Resources Information Center

    McConnell, Scott R.; Wackerle-Hollman, Alisha K.; Roloff, Tracy A.; Rodriguez, Michael

    2014-01-01

    The overall architecture and major components of a measurement system designed and evaluated to support Response to Intervention (RTI) in the areas of language and literacy in early childhood programs are described. Efficient and reliable measurement is essential for implementing any viable RTI system, and implementing such a system in early…

  6. 21 CFR 1020.30 - Diagnostic x-ray systems and their major components.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... irradiation. Diagnostic source assembly means the tube housing assembly with a beam-limiting device attached. Diagnostic x-ray system means an x-ray system designed for irradiation of any part of the human body for the... diagnostic source assembly. Fluoroscopic irradiation time means the cumulative duration during an examination...

  7. 21 CFR 1020.30 - Diagnostic x-ray systems and their major components.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... irradiation. Diagnostic source assembly means the tube housing assembly with a beam-limiting device attached. Diagnostic x-ray system means an x-ray system designed for irradiation of any part of the human body for the... diagnostic source assembly. Fluoroscopic irradiation time means the cumulative duration during an examination...

  8. 21 CFR 1020.30 - Diagnostic x-ray systems and their major components.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... irradiation. Diagnostic source assembly means the tube housing assembly with a beam-limiting device attached. Diagnostic x-ray system means an x-ray system designed for irradiation of any part of the human body for the... diagnostic source assembly. Fluoroscopic irradiation time means the cumulative duration during an examination...

  9. Prime Contract Awards Over $25,000 by Major System, Contractor and State, FY83.

    DTIC Science & Technology

    1983-01-01

    SERVICES 3,074 VO R513 STUDIES/FEASIBILITY - NON- CONSTRUCTION 125 VO T013 TECHNICAL WRITING 1,347 VO 1560 AIRFRAME STRUCTURAL COMPONENTS 6,825 VO 1620...INC NCAR 1670 PARACHUTES RECOVERY SYS AND TIE DOWN EQ 49 ROCKWELL INTERNATIONAL CORP CALIF Y19 CONSTR: CONSTRUCTION /OTHER AIRFIELD STRUCTURES 28,480...INC NEW Y 1560 AIRFRAME STRUCTURAL COMPONENTS 36 GANAR INDUSTRIES I NC CALIF 1680 MISCL AIRCRAFT ACCESSORIES COMPONENTS 180 GARRETT CONSTRUCTION CO

  10. KENNEDY SPACE CENTER, FLA. - During power-up of the orbiter Discovery in the Orbiter Processing Facility, a technician (left) looks at the circuit breaker lights in the cabin. Discovery has been undergoing Orbiter Major Modifications in the past year, ranging from wiring, control panels and black boxes to gaseous and fluid systems tubing and components. These systems were deserviced, disassembled, inspected, modified, reassembled, checked out and reserviced, as were most other systems onboard. The work includes the installation of the Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.”

    NASA Image and Video Library

    2003-08-27

    KENNEDY SPACE CENTER, FLA. - During power-up of the orbiter Discovery in the Orbiter Processing Facility, a technician (left) looks at the circuit breaker lights in the cabin. Discovery has been undergoing Orbiter Major Modifications in the past year, ranging from wiring, control panels and black boxes to gaseous and fluid systems tubing and components. These systems were deserviced, disassembled, inspected, modified, reassembled, checked out and reserviced, as were most other systems onboard. The work includes the installation of the Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.”

  11. Overview of NASA GRC Electrified Aircraft Propulsion Systems Analysis Methods

    NASA Technical Reports Server (NTRS)

    Schnulo, Sydney

    2017-01-01

    The accurate modeling and analysis of electrified aircraft propulsion concepts require intricate subsystem system component coupling. The major challenge in electrified aircraft propulsion concept modeling lies in understanding how the subsystems "talk" to each other and the dependencies they have on one another.

  12. 48 CFR 207.106 - Additional requirements for major systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... of complete technical data packages. (viii) Periodic competitions for subsystem upgrades. (ix... Government to use technical data to competitively reprocure identical items or components of the system if... otherwise entitled to unlimited rights in technical data. (B) If the contracting officer makes a...

  13. 48 CFR 207.106 - Additional requirements for major systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... of complete technical data packages. (viii) Periodic competitions for subsystem upgrades. (ix... Government to use technical data to competitively reprocure identical items or components of the system if... otherwise entitled to unlimited rights in technical data. (B) If the contracting officer makes a...

  14. 48 CFR 207.106 - Additional requirements for major systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... of complete technical data packages. (viii) Periodic competitions for subsystem upgrades. (ix... Government to use technical data to competitively reprocure identical items or components of the system if... otherwise entitled to unlimited rights in technical data. (B) If the contracting officer makes a...

  15. 48 CFR 207.106 - Additional requirements for major systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... of complete technical data packages. (viii) Periodic competitions for subsystem upgrades. (ix... Government to use technical data to competitively reprocure identical items or components of the system if... otherwise entitled to unlimited rights in technical data. (B) If the contracting officer makes a...

  16. 48 CFR 207.106 - Additional requirements for major systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... of complete technical data packages. (viii) Periodic competitions for subsystem upgrades. (ix... Government to use technical data to competitively reprocure identical items or components of the system if... otherwise entitled to unlimited rights in technical data. (B) If the contracting officer makes a...

  17. A computer-based time study system for timber harvesting operations

    Treesearch

    Jingxin Wang; Joe McNeel; John Baumgras

    2003-01-01

    A computer-based time study system was developed for timber harvesting operations. Object-oriented techniques were used to model and design the system. The front-end of the time study system resides on the MS Windows CE and the back-end is supported by MS Access. The system consists of three major components: a handheld system, data transfer interface, and data storage...

  18. Energy Conversion Alternatives Study (ECAS), Westinghouse phase 1. Volume 8: Open-cycle MHD. [energy conversion efficiency and design analysis of electric power plants employing magnetohydrodynamics

    NASA Technical Reports Server (NTRS)

    Hoover, D. Q.

    1976-01-01

    Electric power plant costs and efficiencies are presented for three basic open-cycle MHD systems: (1) direct coal fired system, (2) a system with a separately fired air heater, and (3) a system burning low-Btu gas from an integrated gasifier. Power plant designs were developed corresponding to the basic cases with variation of major parameters for which major system components were sized and costed. Flow diagrams describing each design are presented. A discussion of the limitations of each design is made within the framework of the assumptions made.

  19. Risk Analysis using Corrosion Rate Parameter on Gas Transmission Pipeline

    NASA Astrophysics Data System (ADS)

    Sasikirono, B.; Kim, S. J.; Haryadi, G. D.; Huda, A.

    2017-05-01

    In the oil and gas industry, the pipeline is a major component in the transmission and distribution process of oil and gas. Oil and gas distribution process sometimes performed past the pipeline across the various types of environmental conditions. Therefore, in the transmission and distribution process of oil and gas, a pipeline should operate safely so that it does not harm the surrounding environment. Corrosion is still a major cause of failure in some components of the equipment in a production facility. In pipeline systems, corrosion can cause failures in the wall and damage to the pipeline. Therefore it takes care and periodic inspections or checks on the pipeline system. Every production facility in an industry has a level of risk for damage which is a result of the opportunities and consequences of damage caused. The purpose of this research is to analyze the level of risk of 20-inch Natural Gas Transmission Pipeline using Risk-based inspection semi-quantitative based on API 581 associated with the likelihood of failure and the consequences of the failure of a component of the equipment. Then the result is used to determine the next inspection plans. Nine pipeline components were observed, such as a straight pipes inlet, connection tee, and straight pipes outlet. The risk assessment level of the nine pipeline’s components is presented in a risk matrix. The risk level of components is examined at medium risk levels. The failure mechanism that is used in this research is the mechanism of thinning. Based on the results of corrosion rate calculation, remaining pipeline components age can be obtained, so the remaining lifetime of pipeline components are known. The calculation of remaining lifetime obtained and the results vary for each component. Next step is planning the inspection of pipeline components by NDT external methods.

  20. Les récepteurs

    NASA Astrophysics Data System (ADS)

    Picard, P.; Pezzani, J.

    2011-04-01

    The receiver is the major element in the reception chain and makes the transition between the antenna and the data analysis systems. In radioastronomy there are few different receiver types. Major receiver components are described and the various terms and definitions used in the receiver field and necessary to specify a receiver or to correctly understand its characteristics are explained and detailed.

  1. Teaching Data Analysis with Interactive Visual Narratives

    ERIC Educational Resources Information Center

    Saundage, Dilal; Cybulski, Jacob L.; Keller, Susan; Dharmasena, Lasitha

    2016-01-01

    Data analysis is a major part of business analytics (BA), which refers to the skills, methods, and technologies that enable managers to make swift, quality decisions based on large amounts of data. BA has become a major component of Information Systems (IS) courses all over the world. The challenge for IS educators is to teach data analysis--the…

  2. Waterflood control system for maximizing total oil recovery

    DOEpatents

    Patzek, Tadeusz Wiktor; Silin, Dimitriy Borisovic; De, Asoke Kumar

    2005-06-07

    A control system and method for determining optimal fluid injection pressure is based upon a model of a growing hydrofracture due to waterflood injection pressure. This model is used to develop a control system optimizing the injection pressure by using a prescribed injection goal coupled with the historical times, pressures, and volume of injected fluid at a single well. In this control method, the historical data is used to derive two major flow components: the transitional component, where cumulative injection volume is scaled as the square root of time, and a steady-state breakthrough component, which scales linearly with respect to time. These components provide diagnostic information and allow for the prevention of rapid fracture growth and associated massive water break through that is an important part of a successful waterflood, thereby extending the life of both injection and associated production wells in waterflood secondary oil recovery operations.

  3. Waterflood control system for maximizing total oil recovery

    DOEpatents

    Patzek, Tadeusz Wiktor [Oakland, CA; Silin, Dimitriy Borisovich [Pleasant Hill, CA; De, Asoke Kumar [San Jose, CA

    2007-07-24

    A control system and method for determining optimal fluid injection pressure is based upon a model of a growing hydrofracture due to waterflood injection pressure. This model is used to develop a control system optimizing the injection pressure by using a prescribed injection goal coupled with the historical times, pressures, and volume of injected fluid at a single well. In this control method, the historical data is used to derive two major flow components: the transitional component, where cumulative injection volume is scaled as the square root of time, and a steady-state breakthrough component, which scales linearly with respect to time. These components provide diagnostic information and allow for the prevention of rapid fracture growth and associated massive water break through that is an important part of a successful waterflood, thereby extending the life of both injection and associated production wells in waterflood secondary oil recovery operations.

  4. Command module/service module reaction control subsystem assessment

    NASA Technical Reports Server (NTRS)

    Weary, D. P.

    1971-01-01

    Detailed review of component failure histories, qualification adequacy, manufacturing flow, checkout requirements and flow, ground support equipment interfaces, subsystem interface verification, protective devices, and component design did not reveal major weaknesses in the command service module (CSM) reaction control system (RCS). No changes to the CSM RCS were recommended. The assessment reaffirmed the adequacy of the CSM RCS for future Apollo missions.

  5. Robotic sampling system for an unmanned Mars mission

    NASA Technical Reports Server (NTRS)

    Chun, Wendell

    1989-01-01

    A major robotics opportunity for NASA will be the Mars Rover/Sample Return Mission which could be launched as early as the 1990s. The exploratory portion of this mission will include two autonomous subsystems: the rover vehicle and a sample handling system. The sample handling system is the key to the process of collecting Martian soils. This system could include a core drill, a general-purpose manipulator, tools, containers, a return canister, certification hardware and a labeling system. Integrated into a functional package, the sample handling system is analogous to a complex robotic workcell. Discussed here are the different components of the system, their interfaces, forseeable problem areas and many options based on the scientific goals of the mission. The various interfaces in the sample handling process (component to component and handling system to rover) will be a major engineering effort. Two critical evaluation criteria that will be imposed on the system are flexibility and reliability. It needs to be flexible enough to adapt to different scenarios and environments and acquire the most desirable specimens for return to Earth. Scientists may decide to change the distribution and ratio of core samples to rock samples in the canister. The long distance and duration of this planetary mission places a reliability burden on the hardware. The communication time delay between Earth and Mars minimizes operator interaction (teleoperation, supervisory modes) with the sample handler. An intelligent system will be required to plan the actions, make sample choices, interpret sensor inputs, and query unknown surroundings. A combination of autonomous functions and supervised movements will be integrated into the sample handling system.

  6. High Stakes Assessment: A Local District Perspective.

    ERIC Educational Resources Information Center

    Oldham, Ben R.

    The Kentucky Education Reform Act legislated by the 1990 General Assembly created a high-stakes school performance accountability system to monitor the progress of implementation. One major component of the accountability system is a schedule of consequences designed to reward those schools making sufficient progress in improving student…

  7. An Implementation Model for Integrated Learning Systems.

    ERIC Educational Resources Information Center

    Mills, Steven C.; Ragan, Tillman R.

    This paper describes the development, validation, and research application of the Computer-Delivered Instruction Configuration Matrix (CDICM), an instrument for evaluating the implementation of Integrated Learning Systems (ILS). The CDICM consists of a 15-item checklist, describing the major components of implementation of ILS technology, to be…

  8. Integrated arterial and freeway operation control strategies for IVHS advanced traffic management systems : research report

    DOT National Transportation Integrated Search

    1998-09-01

    The main focus of this study is congestion, primarily that occurring on freeway corridors in metropolitan areas. Lack of coordination in the operation of various components of the system is often a major source of inefficiency, : resulting in greater...

  9. A minimum cost tolerance allocation method for rocket engines and robust rocket engine design

    NASA Technical Reports Server (NTRS)

    Gerth, Richard J.

    1993-01-01

    Rocket engine design follows three phases: systems design, parameter design, and tolerance design. Systems design and parameter design are most effectively conducted in a concurrent engineering (CE) environment that utilize methods such as Quality Function Deployment and Taguchi methods. However, tolerance allocation remains an art driven by experience, handbooks, and rules of thumb. It was desirable to develop and optimization approach to tolerancing. The case study engine was the STME gas generator cycle. The design of the major components had been completed and the functional relationship between the component tolerances and system performance had been computed using the Generic Power Balance model. The system performance nominals (thrust, MR, and Isp) and tolerances were already specified, as were an initial set of component tolerances. However, the question was whether there existed an optimal combination of tolerances that would result in the minimum cost without any degradation in system performance.

  10. Integration of Decentralized Thermal Storages Within District Heating (DH) Networks

    NASA Astrophysics Data System (ADS)

    Schuchardt, Georg K.

    2016-12-01

    Thermal Storages and Thermal Accumulators are an important component within District Heating (DH) systems, adding flexibility and offering additional business opportunities for these systems. Furthermore, these components have a major impact on the energy and exergy efficiency as well as the heat losses of the heat distribution system. Especially the integration of Thermal Storages within ill-conditioned parts of the overall DH system enhances the efficiency of the heat distribution. Regarding an illustrative and simplified example for a DH system, the interactions of different heat storage concepts (centralized and decentralized) and the heat losses, energy and exergy efficiencies will be examined by considering the thermal state of the heat distribution network.

  11. Development Of Autonomous Systems

    NASA Astrophysics Data System (ADS)

    Kanade, Takeo

    1989-03-01

    In the last several years at the Robotics Institute of Carnegie Mellon University, we have been working on two projects for developing autonomous systems: Nablab for Autonomous Land Vehicle and Ambler for Mars Rover. These two systems are for different purposes: the Navlab is a four-wheeled vehicle (van) for road and open terrain navigation, and the Ambler is a six-legged locomotor for Mars exploration. The two projects, however, share many common aspects. Both are large-scale integrated systems for navigation. In addition to the development of individual components (eg., construction and control of the vehicle, vision and perception, and planning), integration of those component technologies into a system by means of an appropriate architecture is a major issue.

  12. An Analysis of the Fragmented Foster Care System with a View toward Systemic Reconstruction: A Review of the Literature.

    ERIC Educational Resources Information Center

    Leach, John William

    Relevant research analyzing the major components of the foster care system is reviewed and critiqued. The research suggests that children are entering the foster care system with a greater severity of psychosocial disorders than in previous years. Regardless of the problems of foster children, empathic and flexible foster parents have a greater…

  13. Food Management System--Daily Production Reports: General Description and Users Guide. Project SIMU-School: Dallas Component.

    ERIC Educational Resources Information Center

    Cronshey, Raymond W.; Dunklau, M. William

    This booklet describes the Daily Production Reports subsystem of the School Food Management System, a computer program package developed as one part of a family of educational management systems. The Daily Production Reports system produces two major types of reports on a daily basis. Business Analysis Reports display all food service costs, as…

  14. US Integrated Ocean Observing System (IOOS°): Delivering Benefits to Science and Society

    NASA Astrophysics Data System (ADS)

    Willis, Z. S.

    2011-12-01

    The United States Integrated Ocean Observing System (IOOS°) is a user-driven, coordinated network of people, organizations, and technology that generate and disseminate continuous data about our coastal waters, Great Lakes, and oceans supported by strong research and development activities. IOOS° is our Eyes on our Oceans, Coasts and Great Lakes that enable the United States to track, predict, manage, and adapt to changes in our marine environment and deliver critical information to decision makers to improve safety, enhance our economy and protect our environment. IOOS provides a major shift in the approach to ocean observing by drawing together the vast network of disparate federal and non-federal observing systems to produce a cohesive suite of data, information, and products on a sufficient geographic and temporal scale to support decision-making. Two interdependent components constitute the U.S. IOOS: (1) the global ocean component, and (2) the coastal component. The strength of IOOS is in its partnerships, starting with the federal agencies, the partnerships extend internationally for the global component and to the local level for the coastal component. The coastal component includes the national set of observations for the U.S. Ocean, Coasts and Great Lakes, a network of Regional Associations that are establishing Regional Coastal Ocean Observing Systems (RCOOS) and the Alliance for Coastal Technologies (ACT). The U.S. IOOS is our nation's contribution to the Global Ocean Observing System (GOOS) - the ocean component of the Global Earth Observation System of Systems (GEOSS).

  15. A Proposed Concentration Curriculum Design for Big Data Analytics for Information Systems Students

    ERIC Educational Resources Information Center

    Molluzzo, John C.; Lawler, James P.

    2015-01-01

    Big Data is becoming a critical component of the Information Systems curriculum. Educators are enhancing gradually the concentration curriculum for Big Data in schools of computer science and information systems. This paper proposes a creative curriculum design for Big Data Analytics for a program at a major metropolitan university. The design…

  16. A STORAGE AND RETRIEVAL SYSTEM FOR DOCUMENTS IN INSTRUCTIONAL RESOURCES. REPORT NO. 13.

    ERIC Educational Resources Information Center

    DIAMOND, ROBERT M.; LEE, BERTA GRATTAN

    IN ORDER TO IMPROVE INSTRUCTION WITHIN TWO-YEAR LOWER DIVISION COURSES, A COMPREHENSIVE RESOURCE LIBRARY WAS DEVELOPED AND A SIMPLIFIED CATALOGING AND INFORMATION RETRIEVAL SYSTEM WAS APPLIED TO IT. THE ROYAL MCBEE "KEYDEX" SYSTEM, CONTAINING THREE MAJOR COMPONENTS--A PUNCH MACHINE, FILE CARDS, AND A LIGHT BOX--WAS USED. CARDS WERE HEADED WITH KEY…

  17. Profiling study of the major and minor components of kaffir lime oil (Citrus hystrix DC.) in the fractional distillation process

    PubMed Central

    Warsito, Warsito; Palungan, Maimunah Hindun; Utomo, Edy Priyo

    2017-01-01

    Introduction Essential oil is consisting of complex component. It is divided into major and minor component. Therefore, this study aims to examine the distribution of major and minor components on Kaffir lime oil by using fractional distillation. Fractional distillation and distributional analysis of components within fractions have been performed on kaffir lime oil (Citrus hystrix DC.). Methods Fractional distillation was performed by using PiloDist 104-VTU, column length of 2 m (number of plate 120), the system pressure was set on 5 and 10 mBar, while the reflux ratio varied on 10/10, 20/10 and 60/10, and the chemical composition analysis was done by using GC-MS. Chemical composition of the distillated lime oil consisted of mix-twigs and leaves that composed of 20 compounds, with five main components β-citronellal (46.40%), L-linalool (13.11%), β-citronellol (11.03%), citronelyl acetate (6.76%) and sabinen (5.91%). Results The optimum conditions for fractional distillation were obtained at 5 mBar pressure with reflux ratio of 10/10. Components of β -citronellal and L-linalool were distributed in the fraction-1 to fraction 9, hydrocarbon monoterpenes components were distributed only on the fraction-1 to fraction 4, while the oxygenated monoterpenes components dominated the fraction-5 to fraction-9. Conclusion The highest level of β-citronellal was 84.86% (fraction-7), L-linalool 20.13% (fraction-5), sabinen 19.83% (fraction-1), and the component level of 4-terpeneol, β-citronellol and sitronelyl acetate respectively 7.16%; 12.27%; 5.22% (fraction-9). PMID:29187951

  18. 12 CFR 630.20 - Contents of the annual report to investors.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... data. At a minimum, furnish the following combined financial data of the System in comparative columnar... results of operations of System institutions, on a combined basis, for the comparative years required by...) Describe, on a comparative basis, changes in the major components of net interest income. Include a...

  19. 12 CFR 630.20 - Contents of the annual report to investors.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... data. At a minimum, furnish the following combined financial data of the System in comparative columnar... results of operations of System institutions, on a combined basis, for the comparative years required by...) Describe, on a comparative basis, changes in the major components of net interest income. Include a...

  20. 12 CFR 630.20 - Contents of the annual report to investors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... data. At a minimum, furnish the following combined financial data of the System in comparative columnar... results of operations of System institutions, on a combined basis, for the comparative years required by...) Describe, on a comparative basis, changes in the major components of net interest income. Include a...

  1. 12 CFR 630.20 - Contents of the annual report to investors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... data. At a minimum, furnish the following combined financial data of the System in comparative columnar... results of operations of System institutions, on a combined basis, for the comparative years required by...) Describe, on a comparative basis, changes in the major components of net interest income. Include a...

  2. 12 CFR 630.20 - Contents of the annual report to investors.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... data. At a minimum, furnish the following combined financial data of the System in comparative columnar... results of operations of System institutions, on a combined basis, for the comparative years required by...) Describe, on a comparative basis, changes in the major components of net interest income. Include a...

  3. Investigation of the impact of the I-94 ATM system on the safety of the I-94 commons high crash area : final report.

    DOT National Transportation Integrated Search

    2014-05-01

    Active Traffic Management (ATM) strategies are being deployed in major cities worldwide to deal with pervasive system : congestion and safety concerns. While such strategies include a diverse array of components, in the Twin Cities metropolitan : are...

  4. Directory of Library Automation Software, Systems, and Services. 1998 Edition.

    ERIC Educational Resources Information Center

    Cibbarelli, Pamela R., Ed.; Cibbarelli, Shawn E., Ed.

    This book includes basic information to locate and compare available options for library automation based on various criteria such as hardware requirements, operating systems, components and applications, and price, and provides the necessary contact information to allow further investigation. The major part of the directory lists 211 software…

  5. SIMULATIONS OF AEROSOLS AND PHOTOCHEMICAL SPECIES WITH THE CMAQ PLUME-IN-GRID MODELING SYSTEM

    EPA Science Inventory

    A plume-in-grid (PinG) method has been an integral component of the CMAQ modeling system and has been designed in order to realistically simulate the relevant processes impacting pollutant concentrations in plumes released from major point sources. In particular, considerable di...

  6. SOME PROBLEMS OF EDUCATIONAL ORGANIZATION IN COMPARATIVE PERSPECTIVE.

    ERIC Educational Resources Information Center

    HILLS, JEAN

    A COMPARATIVE ANALYSIS OF EDUCATIONAL ORGANIZATION WAS MADE WITHIN A THEORETICAL FRAMEWORK INVOLVING SOCIAL SYSTEM TERMS. ATTENTION WAS FOCUSED ON DIFFERENCES AMONG ORGANIZATIONS IN TERMS OF FUNCTIONS PERFORMED FOR SOCIETY. FOUR MAJOR COMPONENTS OF ACTION SYSTEMS USED TO COMPARE SEVERAL ORGANIZATIONS WERE IDENTIFIED AS FOLLOWS--(1) THE ORIENTATION…

  7. Comparison of L-serine uptake by human placental microvillous membrane vesicles and placental villous fragments.

    PubMed

    Brand, A P; Greenwood, S L; Glazier, J D; Bennett, E J; Godfrey, K M; Sibley, C P; Hanson, M A; Lewis, R M

    2010-05-01

    Both syncytiotrophoblast microvillous plasma membrane vesicles (MVM) and placental villous fragments are used to characterize the placental uptake of maternal substrate and to investigate changes in uptake associated with pathological conditions. However, the two techniques have not been directly compared. In this study uptake of (14)C-L-serine was compared in placental villous fragments and in MVM prepared from the same placentas. (14)C-L-serine uptake into MVM vesicles was mediated by System L and System A and smaller unidentified Na(+)-dependent and Na(+)-independent components. In villous fragments an unidentified Na(+)-dependent component mediated the majority of (14)C-L-serine uptake followed by System A and System L. The unidentified Na(+)-independent component of L-serine uptake was not detected in villous fragments. The ratio of System A activity to System L activity was similar in villous fragments and MVM vesicles. However, the unidentified Na(+)-dependent component in villous fragments was significantly higher than that in MVM vesicles. This indicates that the main differences in serine uptake mechanisms identified using the two techniques were not due to differences in System A and System L activity but to differences in the unidentified Na(+)-dependent component. This study suggests that uptake of L-serine into MVM vesicles and villous fragments via Systems A and L is comparable, but that this is not true for all components of L-serine uptake. (c) 2010 Elsevier Ltd. All rights reserved.

  8. Mars Science Laboratory Spacecraft Assembled for Testing

    NASA Image and Video Library

    2008-11-19

    The major components of NASA Mars Science Laboratory spacecraft -- cruise stage atop the aeroshell, which has the descent stage and rover inside -- were connected together in October 2008 for several weeks of system testing.

  9. Analysis of Technology for Solid State Coherent Lidar

    NASA Technical Reports Server (NTRS)

    Amzajerdian, Farzin

    1997-01-01

    Over the past few years, considerable advances have been made in the areas of the diode-pumped, eye-safe, solid state lasers, wide bandwidth, semiconductor detectors operating in the near-infrared region. These advances have created new possibilities for the development of low-cost, reliable, and compact coherent lidar systems for measurements of atmospheric winds and aerosol backscattering from a space-based platform. The work performed by the UAH personnel concentrated on design and analyses of solid state pulsed coherent lidar systems capable of measuring atmospheric winds from space, and design and perform laboratory experiments and measurements in support of solid state laser radar remote sensing systems which are to be designed, deployed, and used by NASA to measure atmospheric processes and constituents. A lidar testbed system was designed and analyzed by considering the major space operational and environmental requirements, and its associated physical constraints. The lidar optical system includes a wedge scanner and the compact telescope designed by the UAH personnel. The other major optical components included in the design and analyses were: polarizing beam splitter, routing mirrors, wave plates, signal beam derotator, and lag angle compensator. The testbed lidar optical train was designed and analyzed, and different design options for mounting and packaging the lidar subsystems and components and support structure were investigated. All the optical components are to be mounted in a stress-free and stable manner to allow easy integration and alignment, and long term stability. This lidar system is also intended to be used for evaluating the performance of various lidar subsystems and components that are to be integrated into a flight unit and for demonstrating the integrity of the signal processing algorithms by performing actual atmospheric measurements from a ground station.

  10. Global Coordinates and Exact Aberration Calculations Applied to Physical Optics Modeling of Complex Optical Systems

    NASA Astrophysics Data System (ADS)

    Lawrence, G.; Barnard, C.; Viswanathan, V.

    1986-11-01

    Historically, wave optics computer codes have been paraxial in nature. Folded systems could be modeled by "unfolding" the optical system. Calculation of optical aberrations is, in general, left for the analyst to do with off-line codes. While such paraxial codes were adequate for the simpler systems being studied 10 years ago, current problems such as phased arrays, ring resonators, coupled resonators, and grazing incidence optics require a major advance in analytical capability. This paper describes extension of the physical optics codes GLAD and GLAD V to include a global coordinate system and exact ray aberration calculations. The global coordinate system allows components to be positioned and rotated arbitrarily. Exact aberrations are calculated for components in aligned or misaligned configurations by using ray tracing to compute optical path differences and diffraction propagation. Optical path lengths between components and beam rotations in complex mirror systems are calculated accurately so that coherent interactions in phased arrays and coupled devices may be treated correctly.

  11. Working on reform. How workers' compensation medical care is affected by health care reform.

    PubMed Central

    Himmelstein, J; Rest, K

    1996-01-01

    The medical component of workers' compensation programs-now costing over $24 billion annually-and the rest of the nation's medical care system are linked. They share the same patients and providers. They provide similar benefits and services. And they struggle over who should pay for what. Clearly, health care reform and restructuring will have a major impact on the operation and expenditures of the workers' compensation system. For a brief period, during the 1994 national health care reform debate, these two systems were part of the same federal policy development and legislative process. With comprehensive health care reform no longer on the horizon, states now are tackling both workers' compensation and medical system reforms on their own. This paper reviews the major issues federal and state policy makers face as they consider reforms affecting the relationship between workers' compensation and traditional health insurance. What is the relationship of the workers' compensation cost crisis to that in general health care? What strategies are being considered by states involved in reforming the medical component of workers compensation? What are the major policy implications of these strategies? Images p13-a p14-a p15-a p16-a p18-a p19-a p20-a p22-a p24-a PMID:8610187

  12. PHOTOCHEMICAL ALTERATION OF DISSOLVED ORGANIC MATTER: EFFECTS ON THE CONCENTRATION AND ACIDITIES OF IONIZABLE SITES IN DISSOLVED ORGANIC MATTER IN THE SATILLA RIVER OF GEORGIA, USA

    EPA Science Inventory

    The acid-base properties of humic substances, the major component of dissolved organic matter (DOM), area major control on the alkalinity, or acid neutralizing capacity of freshwater systems. Alkalinity is one of the fundamental parameters measured in aquatic sciences, and is an ...

  13. Research Objectives for Human Missions in the Proving Ground of Cis-Lunar Space

    NASA Technical Reports Server (NTRS)

    Niles, P. B.; Eppler, D. B.; Kennedy, K. J.; Lewis, R.; Spann, J. F.; Sullivan, T. A.

    2016-01-01

    Beginning in as early as 2023, crewed missions beyond low Earth orbit will begin enabled by the new capabilities of the SLS and Orion vehicles. This will initiate the "Proving Ground" phase of human exploration with Mars as an ultimate destination. The primary goal of the Proving Ground is to demonstrate the capability of suitably long duration spaceflight without need of continuous support from Earth, i.e. become Earth Independent. A major component of the Proving Ground phase is to conduct research activities aimed at accomplishing major objectives selected from a wide variety of disciplines including but not limited to: Astronomy, Heliophysics, Fundamental Physics, Planetary Science, Earth Science, Human Systems, Fundamental Space Biology, Microgravity, and In A major component of the Proving Ground phase is to conduct research activities aimed at accomplishing major objectives selected from a wide variety of disciplines including but not limited to: Astronomy, Heliophysics, Fundamental Physics, Planetary Science, Earth Science, Human Systems, Fundamental Space Biology, Microgravity, and In Situ Resource Utilization. Mapping and prioritizing the most important objectives from these disciplines will provide a strong foundation for establishing the architecture to be utilized in the Proving Ground.

  14. Altimetry data over trenches and island-arcs and convection in the mantle

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Transfer function techniques were developed to calculate the isostatic component of the geoid signal over trench/island arc/back arc systems. Removal of this isostatic component from geoid profiles determined by GEOS 3 radar altimetry leaves a residual geoid that can be attributed to the effect of mass inhomogeneities below the depth of compensation. Efforts are underway to extend the analysis to all the major trench/island arc systems of the world in order to provide more detailed understanding of the dynamic processes occurring beneath island arcs.

  15. Software Architecture Evolution

    DTIC Science & Technology

    2013-12-01

    system’s major components occurring via a Java Message Service message bus [69]. This architecture was designed to promote loose coupling of soft- ware...play reconfiguration of the system. The components were Java -based and platform-independent; the interfaces by which they communicated were based on...The MPCS database, a MySQL database used for storing telemetry as well as some other information, such as logs and commanding data [68]. This

  16. Global Combat Support System - Army Increment 2 (GCSS-A Inc 2)

    DTIC Science & Technology

    2016-03-01

    2016 Major Automated Information System Annual Report Global Combat Support System - Army Increment 2 (GCSS-A Inc 2) Defense Acquisition...Secretary of Defense PB - President’s Budget RDT&E - Research, Development, Test, and Evaluation SAE - Service Acquisition Executive TBD - To Be...Date Assigned: Program Information Program Name Global Combat Support System - Army Increment 2 (GCSS-A Inc 2) DoD Component Army Responsible

  17. GMRT servo system : overview of the upgrades

    NASA Astrophysics Data System (ADS)

    Bagde, Shailendra

    The servo system of the GMRT, designed in the early 1990s by BARC and subsequently commissioned in the antennas by 1996, is a classical nested loop control system. Some of its major subsystems are undergoing significant upgrades to increase reliability, reduce maintenance and overcome obsolescence of components. These include the solid-state interlock system, a PC104 based servo control computer, and advanced BLDC drives and motors.

  18. Human factors in air traffic control: problems at the interfaces.

    PubMed

    Shouksmith, George

    2003-10-01

    The triangular ISIS model for describing the operation of human factors in complex sociotechnical organisations or systems is applied in this research to a large international air traffic control system. A large sample of senior Air Traffic Controllers were randomly assigned to small focus discussion groups, whose task was to identify problems occurring at the interfaces of the three major human factor components: individual, system impacts, and social. From these discussions, a number of significant interface problems, which could adversely affect the functioning of the Air Traffic Control System, emerged. The majority of these occurred at the Individual-System Impact and Individual-Social interfaces and involved a perceived need for further interface centered training.

  19. Implementation status of accrual accounting system in health sector.

    PubMed

    Mehrolhassani, Mohammad Hossien; Khayatzadeh-Mahani, Akram; Emami, Mozhgan

    2014-07-29

    Management of financial resources in health systems is one of the major issues of concern for policy makers globally. As a sub-set of financial management, accounting system is of paramount importance. In this paper, which presents part of the results of a wider research project on transition process from a cash accounting system to an accrual accounting system, we look at the impact of components of change on implementation of the new system. Implementing changes is fraught with many obstacles and surveying these challenges will help policy makers to better overcome them. The study applied a quantitative manner in 2012 at Kerman University of Medical Science in Iran. For the evaluation, a teacher made valid questionnaire with Likert scale was used (Cranach's alpha of 0.89) which included 7 change components in accounting system. The study population was 32 subordinate units of Kerman University of Medical Sciences and for data analysis, descriptive and inferential statistics and correlation coefficient in SPSS version 19 were used. Level of effect of all components on the implementation was average downward (5.06±1.86), except for the component "management & leadership (3.46±2.25)" (undesirable from external evaluators' viewpoint) and "technology (6.61±1.92) and work processes (6.35±2.19)" (middle to high from internal evaluators' viewpoint). Results showed that the establishment of accrual accounting system faces infrastructural challenges, especially the components of leadership and management and followers. As such, developing effective measures to overcome implementation obstacles should target these components.

  20. The Orbiter camera payload system's large-format camera and attitude reference system

    NASA Technical Reports Server (NTRS)

    Schardt, B. B.; Mollberg, B. H.

    1985-01-01

    The Orbiter camera payload system (OCPS) is an integrated photographic system carried into earth orbit as a payload in the Space Transportation System (STS) Orbiter vehicle's cargo bay. The major component of the OCPS is a large-format camera (LFC), a precision wide-angle cartographic instrument capable of producing high-resolution stereophotography of great geometric fidelity in multiple base-to-height ratios. A secondary and supporting system to the LFC is the attitude reference system (ARS), a dual-lens stellar camera array (SCA) and camera support structure. The SCA is a 70 mm film system that is rigidly mounted to the LFC lens support structure and, through the simultaneous acquisition of two star fields with each earth viewing LFC frame, makes it possible to precisely determine the pointing of the LFC optical axis with reference to the earth nadir point. Other components complete the current OCPS configuration as a high-precision cartographic data acquisition system. The primary design objective for the OCPS was to maximize system performance characteristics while maintaining a high level of reliability compatible with rocket launch conditions and the on-orbit environment. The full OCPS configuration was launched on a highly successful maiden voyage aboard the STS Orbiter vehicle Challenger on Oct. 5, 1984, as a major payload aboard the STS-41G mission.

  1. The QuakeSim Project: Web Services for Managing Geophysical Data and Applications

    NASA Astrophysics Data System (ADS)

    Pierce, Marlon E.; Fox, Geoffrey C.; Aktas, Mehmet S.; Aydin, Galip; Gadgil, Harshawardhan; Qi, Zhigang; Sayar, Ahmet

    2008-04-01

    We describe our distributed systems research efforts to build the “cyberinfrastructure” components that constitute a geophysical Grid, or more accurately, a Grid of Grids. Service-oriented computing principles are used to build a distributed infrastructure of Web accessible components for accessing data and scientific applications. Our data services fall into two major categories: Archival, database-backed services based around Geographical Information System (GIS) standards from the Open Geospatial Consortium, and streaming services that can be used to filter and route real-time data sources such as Global Positioning System data streams. Execution support services include application execution management services and services for transferring remote files. These data and execution service families are bound together through metadata information and workflow services for service orchestration. Users may access the system through the QuakeSim scientific Web portal, which is built using a portlet component approach.

  2. Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity

    PubMed Central

    Palm, Noah W.; Rosenstein, Rachel K.; Yu, Shuang; Schenten, Dominik; Florsheim, Esther; Medzhitov, Ruslan

    2013-01-01

    SUMMARY Venoms consist of toxic components that are delivered to their victims via bites or stings. Venoms also represent a major class of allergens in humans. Phospholipase A2 (PLA2) is a conserved component of venoms from multiple species and is the major allergen in bee venom. Here we examined how bee venom PLA2 is sensed by the innate immune system and induces a type 2 immune response in mice. We found that bee venom PLA2 induced a T helper type 2 (Th2) cell-type response and group 2 innate lymphoid cell activation via the enzymatic cleavage of membrane phospholipids and release of interleukin-33. Furthermore, we showed that the IgE response to PLA2 could protect mice from future challenge with a near-lethal dose of PLA2. These data suggest that the innate immune system can detect the activity of a conserved component of venoms and induce a protective immune response against a venom toxin. PMID:24210353

  3. Evolution of JAK-STAT Pathway Components: Mechanisms and Role in Immune System Development

    PubMed Central

    Liongue, Clifford; O'Sullivan, Lynda A.; Trengove, Monique C.; Ward, Alister C.

    2012-01-01

    Background Lying downstream of a myriad of cytokine receptors, the Janus kinase (JAK) – Signal transducer and activator of transcription (STAT) pathway is pivotal for the development and function of the immune system, with additional important roles in other biological systems. To gain further insight into immune system evolution, we have performed a comprehensive bioinformatic analysis of the JAK-STAT pathway components, including the key negative regulators of this pathway, the SH2-domain containing tyrosine phosphatase (SHP), Protein inhibitors against Stats (PIAS), and Suppressor of cytokine signaling (SOCS) proteins across a diverse range of organisms. Results Our analysis has demonstrated significant expansion of JAK-STAT pathway components co-incident with the emergence of adaptive immunity, with whole genome duplication being the principal mechanism for generating this additional diversity. In contrast, expansion of upstream cytokine receptors appears to be a pivotal driver for the differential diversification of specific pathway components. Conclusion Diversification of JAK-STAT pathway components during early vertebrate development occurred concurrently with a major expansion of upstream cytokine receptors and two rounds of whole genome duplications. This produced an intricate cell-cell communication system that has made a significant contribution to the evolution of the immune system, particularly the emergence of adaptive immunity. PMID:22412924

  4. Advanced RF Front End Technology

    NASA Technical Reports Server (NTRS)

    Herman, M. I.; Valas, S.; Katehi, L. P. B.

    2001-01-01

    The ability to achieve low-mass low-cost micro/nanospacecraft for Deep Space exploration requires extensive miniaturization of all subsystems. The front end of the Telecommunication subsystem is an area in which major mass (factor of 10) and volume (factor of 100) reduction can be achieved via the development of new silicon based micromachined technology and devices. Major components that make up the front end include single-pole and double-throw switches, diplexer, and solid state power amplifier. JPL's Center For Space Microsystems - System On A Chip (SOAC) Program has addressed the challenges of front end miniaturization (switches and diplexers). Our objectives were to develop the main components that comprise a communication front end and enable integration in a single module that we refer to as a 'cube'. In this paper we will provide the latest status of our Microelectromechanical System (MEMS) switches and surface micromachined filter development. Based on the significant progress achieved we can begin to provide guidelines of the proper system insertion for these emerging technologies. Additional information is contained in the original extended abstract.

  5. Engineering large-scale agent-based systems with consensus

    NASA Technical Reports Server (NTRS)

    Bokma, A.; Slade, A.; Kerridge, S.; Johnson, K.

    1994-01-01

    The paper presents the consensus method for the development of large-scale agent-based systems. Systems can be developed as networks of knowledge based agents (KBA) which engage in a collaborative problem solving effort. The method provides a comprehensive and integrated approach to the development of this type of system. This includes a systematic analysis of user requirements as well as a structured approach to generating a system design which exhibits the desired functionality. There is a direct correspondence between system requirements and design components. The benefits of this approach are that requirements are traceable into design components and code thus facilitating verification. The use of the consensus method with two major test applications showed it to be successful and also provided valuable insight into problems typically associated with the development of large systems.

  6. Using Movies to Analyse Gene Circuit Dynamics in Single Cells

    PubMed Central

    Locke, James CW; Elowitz, Michael B

    2010-01-01

    Preface Many bacterial systems rely on dynamic genetic circuits to control critical processes. A major goal of systems biology is to understand these behaviours in terms of individual genes and their interactions. However, traditional techniques based on population averages wash out critical dynamics that are either unsynchronized between cells or driven by fluctuations, or ‘noise,’ in cellular components. Recently, the combination of time-lapse microscopy, quantitative image analysis, and fluorescent protein reporters has enabled direct observation of multiple cellular components over time in individual cells. In conjunction with mathematical modelling, these techniques are now providing powerful insights into genetic circuit behaviour in diverse microbial systems. PMID:19369953

  7. Coarse-grained component concurrency in Earth system modeling: parallelizing atmospheric radiative transfer in the GFDL AM3 model using the Flexible Modeling System coupling framework

    NASA Astrophysics Data System (ADS)

    Balaji, V.; Benson, Rusty; Wyman, Bruce; Held, Isaac

    2016-10-01

    Climate models represent a large variety of processes on a variety of timescales and space scales, a canonical example of multi-physics multi-scale modeling. Current hardware trends, such as Graphical Processing Units (GPUs) and Many Integrated Core (MIC) chips, are based on, at best, marginal increases in clock speed, coupled with vast increases in concurrency, particularly at the fine grain. Multi-physics codes face particular challenges in achieving fine-grained concurrency, as different physics and dynamics components have different computational profiles, and universal solutions are hard to come by. We propose here one approach for multi-physics codes. These codes are typically structured as components interacting via software frameworks. The component structure of a typical Earth system model consists of a hierarchical and recursive tree of components, each representing a different climate process or dynamical system. This recursive structure generally encompasses a modest level of concurrency at the highest level (e.g., atmosphere and ocean on different processor sets) with serial organization underneath. We propose to extend concurrency much further by running more and more lower- and higher-level components in parallel with each other. Each component can further be parallelized on the fine grain, potentially offering a major increase in the scalability of Earth system models. We present here first results from this approach, called coarse-grained component concurrency, or CCC. Within the Geophysical Fluid Dynamics Laboratory (GFDL) Flexible Modeling System (FMS), the atmospheric radiative transfer component has been configured to run in parallel with a composite component consisting of every other atmospheric component, including the atmospheric dynamics and all other atmospheric physics components. We will explore the algorithmic challenges involved in such an approach, and present results from such simulations. Plans to achieve even greater levels of coarse-grained concurrency by extending this approach within other components, such as the ocean, will be discussed.

  8. Design evaluation: S-band exciters

    NASA Technical Reports Server (NTRS)

    1974-01-01

    A design evaluation study was conducted to produce S-band exciter (SBE) system to provide a highly stable phase or modulated carrier for transmission to spacecraft. The exciter is part of an S-band receiver/exciter/ranging system at Spaceflight Tracking and Data Network (STDN) ground stations. The major features of the system are defined. Circuit diagrams of the electronic components are provided.

  9. Towards Web Service-Based Educational Systems

    ERIC Educational Resources Information Center

    Sampson, Demetrios G.

    2005-01-01

    The need for designing the next generation of web service-based educational systems with the ability of integrating components from different tools and platforms is now recognised as the major challenge in advanced learning technologies. In this paper, we discuss this issue and we present the conceptual design of such environment, referred to as…

  10. Computer-Aided College Algebra: Learning Components that Students Find Beneficial

    ERIC Educational Resources Information Center

    Aichele, Douglas B.; Francisco, Cynthia; Utley, Juliana; Wescoatt, Benjamin

    2011-01-01

    A mixed-method study was conducted during the Fall 2008 semester to better understand the experiences of students participating in computer-aided instruction of College Algebra using the software MyMathLab. The learning environment included a computer learning system for the majority of the instruction, a support system via focus groups (weekly…

  11. A Cross-Cultural Study of Japanese Education.

    ERIC Educational Resources Information Center

    Petry, John R.

    The homogeneity of the Japanese people is a major component in their educational achievements. The success of the educational system is linked to various factors, such as the state of the national health, the excellence of the transportation system, a common language, and other cultural attitudes and values. Parents are considered responsible for…

  12. A Proposed Programming System for Knuth's Mix Computer.

    ERIC Educational Resources Information Center

    Akers, Max Neil

    A programing system using a hypothetical computer is proposed for use in teaching machine and assembly language programing courses. Major components such as monitor, assembler, interpreter, grader, and diagnostics are described. The interpreter is programed and documented for use on an IBM 360/67 computer. The interpreter can be used for teaching…

  13. The Political Construction of Mass Schooling: European Origins and Worldwide Institutionalization.

    ERIC Educational Resources Information Center

    Ramirez, Francisco O.; Boli, John

    1987-01-01

    Examines the origins of state educational systems in Europe in the nineteenth century and the institutionalization of mass education throughout the world in the twentieth century. Shows how construction of mass educational systems became a major and indispensable component of every modern state's nation building activity. Discusses the usefulness…

  14. Training Evaluation as an Integral Component of Training for Performance.

    ERIC Educational Resources Information Center

    Lapp, H. J., Jr.

    A training evaluation system should address four major areas: reaction, learning, behavior, and results. The training evaluation system at GPU Nuclear Corporation addresses each of these areas through practical approaches such as course and program evaluation. GPU's program evaluation instrument uses a Likert-type scale to assess task development,…

  15. Inside EUREKA. The California Career Information System.

    ERIC Educational Resources Information Center

    Banaghan, Bill; And Others

    A computerized career information system named EUREKA has been developed for California. It originated in 1975-76 under the direction of the Bay Area Computer Educators and since that time has received state and VEA funding. It consists of two major components, Quest and information files. Quest asks users twenty-one questions in order to…

  16. Built-In Data-Flow Integration Testing in Large-Scale Component-Based Systems

    NASA Astrophysics Data System (ADS)

    Piel, Éric; Gonzalez-Sanchez, Alberto; Gross, Hans-Gerhard

    Modern large-scale component-based applications and service ecosystems are built following a number of different component models and architectural styles, such as the data-flow architectural style. In this style, each building block receives data from a previous one in the flow and sends output data to other components. This organisation expresses information flows adequately, and also favours decoupling between the components, leading to easier maintenance and quicker evolution of the system. Integration testing is a major means to ensure the quality of large systems. Their size and complexity, together with the fact that they are developed and maintained by several stake holders, make Built-In Testing (BIT) an attractive approach to manage their integration testing. However, so far no technique has been proposed that combines BIT and data-flow integration testing. We have introduced the notion of a virtual component in order to realize such a combination. It permits to define the behaviour of several components assembled to process a flow of data, using BIT. Test-cases are defined in a way that they are simple to write and flexible to adapt. We present two implementations of our proposed virtual component integration testing technique, and we extend our previous proposal to detect and handle errors in the definition by the user. The evaluation of the virtual component testing approach suggests that more issues can be detected in systems with data-flows than through other integration testing approaches.

  17. Identification of high performance and component technology for space electrical power systems for use beyond the year 2000

    NASA Technical Reports Server (NTRS)

    Maisel, James E.

    1988-01-01

    Addressed are some of the space electrical power system technologies that should be developed for the U.S. space program to remain competitive in the 21st century. A brief historical overview of some U.S. manned/unmanned spacecraft power systems is discussed to establish the fact that electrical systems are and will continue to become more sophisticated as the power levels appoach those on the ground. Adaptive/Expert power systems that can function in an extraterrestrial environment will be required to take an appropriate action during electrical faults so that the impact is minimal. Manhours can be reduced significantly by relinquishing tedious routine system component maintenance to the adaptive/expert system. By cataloging component signatures over time this system can set a flag for a premature component failure and thus possibly avoid a major fault. High frequency operation is important if the electrical power system mass is to be cut significantly. High power semiconductor or vacuum switching components will be required to meet future power demands. System mass tradeoffs have been investigated in terms of operating at high temperature, efficiency, voltage regulation, and system reliability. High temperature semiconductors will be required. Silicon carbide materials will operate at a temperature around 1000 K and the diamond material up to 1300 K. The driver for elevated temperature operation is that radiator mass is reduced significantly because of inverse temperature to the fourth power.

  18. Feasibility study of an Integrated Program for Aerospace vehicle Design (IPAD). Volume 1B: Concise review

    NASA Technical Reports Server (NTRS)

    Miller, R. E., Jr.; Southall, J. W.; Kawaguchi, A. S.; Redhed, D. D.

    1973-01-01

    Reports on the design process, support of the design process, IPAD System design catalog of IPAD technical program elements, IPAD System development and operation, and IPAD benefits and impact are concisely reviewed. The approach used to define the design is described. Major activities performed during the product development cycle are identified. The computer system requirements necessary to support the design process are given as computational requirements of the host system, technical program elements and system features. The IPAD computer system design is presented as concepts, a functional description and an organizational diagram of its major components. The cost and schedules and a three phase plan for IPAD implementation are presented. The benefits and impact of IPAD technology are discussed.

  19. Response of selected plant and insect species to simulated SRM exhaust mixtures and to exhaust components from SRM fuels

    NASA Technical Reports Server (NTRS)

    Heck, W. W.

    1980-01-01

    The possible biologic effects of exhaust products from solid rocket motor (SRM) burns associated with the space shuttle are examined. The major components of the exhaust that might have an adverse effect on vegetation, HCl and Al2O3 are studied. Dose response curves for native and cultivated plants and selected insects exposed to simulated exhaust and component chemicals from SRM exhaust are presented. A system for dispensing and monitoring component chemicals of SRM exhaust (HCl and Al2O3) and a system for exposing test plants to simulated SRM exhaust (controlled fuel burns) are described. The effects of HCl, Al2O3, and mixtures of the two on the honeybee, the corn earworm, and the common lacewing and the effects of simulated exhaust on the honeybee are discussed.

  20. Deployer Performance Results for the TSS-1 Mission

    NASA Technical Reports Server (NTRS)

    Marshall, Leland S.; Geiger, Ronald V.

    1995-01-01

    Performance of the Tethered Satellite System (TSS) Deployer during the STS-46 mission (July and August 1992) is analyzed in terms of hardware operation at the component and system level. Although only a limited deployment of the satellite was achieved (256 meters vs 20 kilometers planned), the mission served to verify the basic capability of the Deployer to release, control and retrieve a tethered satellite. - Deployer operational flexibility that was demonstrated during the flight is also addressed. Martin Marietta was the prime contractor for the development of the Deployer, under management of the NASA George C. Marshall Space Flight Center (MSFC). The satellite was provided by Alenia, Torino, Italy under contract to the Agencia Spaziale Italiana (ASI). Proper operation of the avionics components and the majority of mechanisms was observed during the flight. System operations driven by control laws for the deployment and retrieval of the satellite were also successful for the limited deployment distance. Anomalies included separation problems for one of the two umbilical connectors between the Deployer and satellite, tether jamming (at initial Satellite fly-away and at a deployment distance of 224 meters), and a mechanical interference which prevented tether deployment beyond 256 meters. The Deployer was used in several off-nominal conditions to respond to these anomalies, which ultimately enabled a successful satellite retrieval and preservation of hardware integrity for a future re-flight. The paper begins with an introduction defining the significance of the TSS-1 mission. The body of the paper is divided into four major sections: (1) Description of Deployer System and Components, (2) Deployer Components/Systems Demonstrating Successful Operation, (3) Hardware Anomalies and Operational Responses, and (4) Design Modifications for the TSS-1R Re-flight Mission. Conclusions from the TSS-1 mission, including lessons learned are presented at the end of the manuscript.

  1. Challenges of the Open Source Component Marketplace in the Industry

    NASA Astrophysics Data System (ADS)

    Ayala, Claudia; Hauge, Øyvind; Conradi, Reidar; Franch, Xavier; Li, Jingyue; Velle, Ketil Sandanger

    The reuse of Open Source Software components available on the Internet is playing a major role in the development of Component Based Software Systems. Nevertheless, the special nature of the OSS marketplace has taken the “classical” concept of software reuse based on centralized repositories to a completely different arena based on massive reuse over Internet. In this paper we provide an overview of the actual state of the OSS marketplace, and report preliminary findings about how companies interact with this marketplace to reuse OSS components. Such data was gathered from interviews in software companies in Spain and Norway. Based on these results we identify some challenges aimed to improve the industrial reuse of OSS components.

  2. Authentication of virgin olive oil by a novel curve resolution approach combined with visible spectroscopy.

    PubMed

    Ferreiro-González, Marta; Barbero, Gerardo F; Álvarez, José A; Ruiz, Antonio; Palma, Miguel; Ayuso, Jesús

    2017-04-01

    Adulteration of olive oil is not only a major economic fraud but can also have major health implications for consumers. In this study, a combination of visible spectroscopy with a novel multivariate curve resolution method (CR), principal component analysis (PCA) and linear discriminant analysis (LDA) is proposed for the authentication of virgin olive oil (VOO) samples. VOOs are well-known products with the typical properties of a two-component system due to the two main groups of compounds that contribute to the visible spectra (chlorophylls and carotenoids). Application of the proposed CR method to VOO samples provided the two pure-component spectra for the aforementioned families of compounds. A correlation study of the real spectra and the resolved component spectra was carried out for different types of oil samples (n=118). LDA using the correlation coefficients as variables to discriminate samples allowed the authentication of 95% of virgin olive oil samples. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. New frontiers in design synthesis

    NASA Technical Reports Server (NTRS)

    Goldin, D. S.; Venneri, S. L.; Noor, A. K.

    1999-01-01

    The Intelligent Synthesis Environment (ISE), which is one of the major strategic technologies under development at NASA centers and the University of Virginia, is described. One of the major objectives of ISE is to significantly enhance the rapid creation of innovative affordable products and missions. ISE uses a synergistic combination of leading-edge technologies, including high performance computing, high capacity communications and networking, human-centered computing, knowledge-based engineering, computational intelligence, virtual product development, and product information management. The environment will link scientists, design teams, manufacturers, suppliers, and consultants who participate in the mission synthesis as well as in the creation and operation of the aerospace system. It will radically advance the process by which complex science missions are synthesized, and high-tech engineering Systems are designed, manufactured and operated. The five major components critical to ISE are human-centered computing, infrastructure for distributed collaboration, rapid synthesis and simulation tools, life cycle integration and validation, and cultural change in both the engineering and science creative process. The five components and their subelements are described. Related U.S. government programs are outlined and the future impact of ISE on engineering research and education is discussed.

  4. Force of habit: shrubs, trees and contingent evolution of wood anatomical diversity using Croton (Euphorbiaceae) as a model system

    Treesearch

    Rafael Arévalo; Benjamin W. van Ee; Ricarda Riina; Paul E. Berry; Alex C. Wiedenhoeft

    2017-01-01

    Background and Aims Wood is a major innovation of land plants, and is usually a central component of the body plan for two major plant habits: shrubs and trees. Wood anatomical syndromes vary between shrubs and trees, but no prior work has explicitly evaluated the contingent evolution of wood anatomical diversity in the context...

  5. Electrical/electronics working group summary

    NASA Technical Reports Server (NTRS)

    Schoenfeld, A. D.

    1984-01-01

    The electrical/electronics, technology area was considered. It was found that there are no foreseeable circuit or component problems to hinder the implementation of the flywheel energy storage concept. The definition of the major component or technology developments required to permit a technology ready date of 1987 was addressed. Recommendations: motor/generators, suspension electronics, power transfer, power conditioning and distribution, and modeling. An introduction to the area of system engineering is also included.

  6. Solar electric propulsion. [low thrust trajectory control

    NASA Technical Reports Server (NTRS)

    Barbieri, R. W.

    1975-01-01

    The major components of a solar electric propulsion system are discussed and some problems in low thrust mission analysis are detailed. Emphasis is placed on the development of a nominal low thrust trajectory and guidance and navigation aspects.

  7. Interplay between solid Earth and biological evolution

    NASA Astrophysics Data System (ADS)

    Höning, Dennis; Spohn, Tilman

    2017-04-01

    Major shifts in Earth's evolution led to progressive adaptations of the biosphere. Particularly the emergence of continents permitted efficient use of solar energy. However, the widespread evolution of the biosphere fed back to the Earth system, often argued as a cause for the great oxidation event or as an important component in stabilizing Earth's climate. Furthermore, biologically enhanced weathering rates alter the flux of sediments in subduction zones, establishing a potential link to the deep interior. Stably bound water within subducting sediments not only enhances partial melting but further affects the mantle rheology. The mantle responds by enhancing its rates of convection, water outgassing, and subduction. How crucial is the emergence and evolution of life on Earth to these processes, and how would Earth have been evolved without the emergence of life? We here discuss concepts and present models addressing these questions and discuss the biosphere as a major component in evolving Earth system feedback cycles.

  8. Wound Trauma Mediated Inflammatory Signaling Attenuates a Tissue Regenerative Response in MRL/MpJ Mice

    DTIC Science & Technology

    2010-01-01

    multi-system organ failure, and remote organ injury at sites such as the lung, liver , small intestines, and brain, representing major causes of...inflammatory components. The development of systemic inflammation following severe thermal injury has been implicated in immune dysfunction, delayed wound...healing, multi-system organ failure and increased mortality. Methods: In this study, we examined the impact of thermal injury -induced systemic

  9. Performance-based seismic design of nonstructural building components: The next frontier of earthquake engineering

    NASA Astrophysics Data System (ADS)

    Filiatrault, Andre; Sullivan, Timothy

    2014-08-01

    With the development and implementation of performance-based earthquake engineering, harmonization of performance levels between structural and nonstructural components becomes vital. Even if the structural components of a building achieve a continuous or immediate occupancy performance level after a seismic event, failure of architectural, mechanical or electrical components can lower the performance level of the entire building system. This reduction in performance caused by the vulnerability of nonstructural components has been observed during recent earthquakes worldwide. Moreover, nonstructural damage has limited the functionality of critical facilities, such as hospitals, following major seismic events. The investment in nonstructural components and building contents is far greater than that of structural components and framing. Therefore, it is not surprising that in many past earthquakes, losses from damage to nonstructural components have exceeded losses from structural damage. Furthermore, the failure of nonstructural components can become a safety hazard or can hamper the safe movement of occupants evacuating buildings, or of rescue workers entering buildings. In comparison to structural components and systems, there is relatively limited information on the seismic design of nonstructural components. Basic research work in this area has been sparse, and the available codes and guidelines are usually, for the most part, based on past experiences, engineering judgment and intuition, rather than on objective experimental and analytical results. Often, design engineers are forced to start almost from square one after each earthquake event: to observe what went wrong and to try to prevent repetitions. This is a consequence of the empirical nature of current seismic regulations and guidelines for nonstructural components. This review paper summarizes current knowledge on the seismic design and analysis of nonstructural building components, identifying major knowledge gaps that will need to be filled by future research. Furthermore, considering recent trends in earthquake engineering, the paper explores how performance-based seismic design might be conceived for nonstructural components, drawing on recent developments made in the field of seismic design and hinting at the specific considerations required for nonstructural components.

  10. Integrated Personnel and Pay System-Army Increment 2 (IPPS-A Inc 2)

    DTIC Science & Technology

    2016-03-01

    2016 Major Automated Information System Annual Report Integrated Personnel and Pay System-Army Increment 2 (IPPS-A Inc 2) Defense Acquisition...703-325-3747 DSN Phone: 865-2915 DSN Fax: 221-3747 Date Assigned: May 2, 2014 Program Information Program Name Integrated Personnel and Pay System...Program Description The Integrated Personnel and Pay System-Army (IPPS-A) will provide the Army with an integrated, multi-Component (Active, National

  11. Comprehensive dynamic analysis of a bladed disk-turborotor-bearing system

    NASA Astrophysics Data System (ADS)

    Kaushal, Ashok

    The dynamic behavior of a bladed disk-turborotor-bearing system is studied employing analytical, numerical, and experimental methods. The system consists of several subsystems such as turbine disk, blades, bearings, support pedestals etc. In order to completely understand the dynamic behavior of the turborotor system an appropriate model for each individual component of the system is first developed. The individual components are modeled to include various design parameters and the effect of these parameters on the vibrational behavior is studied. The vibration studies on the individual components are carried out using Rayleigh-Ritz method boundary characteristic orthogonal polynomials as assumed shape functions. The individual components are then assembled using the finite element technique. The turborotor system is studied from a system point of view and the natural frequencies and mode shapes are obtained for various rotational speeds. The results show that the natural frequencies of the system are different from those obtained by analyzing individual components, suggesting that a system approach must be adopted for proper design of a turborotor system. The amplitude of vibration and stresses due to harmonic and centrifugal loading on the blades and the disk are also obtained. The results indicate that for the turborotor speed of operation, the centrifugal loading is the major factor in determining the critical stresses in comparison to the gas forces on the blade modeled as harmonic loading. Experimental validation of the analytical model is carried out and suggestions for future work are given.

  12. Major component analysis of dynamic networks of physiologic organ interactions

    NASA Astrophysics Data System (ADS)

    Liu, Kang K. L.; Bartsch, Ronny P.; Ma, Qianli D. Y.; Ivanov, Plamen Ch

    2015-09-01

    The human organism is a complex network of interconnected organ systems, where the behavior of one system affects the dynamics of other systems. Identifying and quantifying dynamical networks of diverse physiologic systems under varied conditions is a challenge due to the complexity in the output dynamics of the individual systems and the transient and nonlinear characteristics of their coupling. We introduce a novel computational method based on the concept of time delay stability and major component analysis to investigate how organ systems interact as a network to coordinate their functions. We analyze a large database of continuously recorded multi-channel physiologic signals from healthy young subjects during night-time sleep. We identify a network of dynamic interactions between key physiologic systems in the human organism. Further, we find that each physiologic state is characterized by a distinct network structure with different relative contribution from individual organ systems to the global network dynamics. Specifically, we observe a gradual decrease in the strength of coupling of heart and respiration to the rest of the network with transition from wake to deep sleep, and in contrast, an increased relative contribution to network dynamics from chin and leg muscle tone and eye movement, demonstrating a robust association between network topology and physiologic function.

  13. Human adaptive immune system Rag2-/-gamma(c)-/- mice.

    PubMed

    Chicha, Laurie; Tussiwand, Roxane; Traggiai, Elisabetta; Mazzucchelli, Luca; Bronz, Lucio; Piffaretti, Jean-Claude; Lanzavecchia, Antonio; Manz, Markus G

    2005-06-01

    Although many biologic principles are conserved in mice and humans, species-specific differences exist, for example, in susceptibility and response to pathogens, that often do not allow direct implementation of findings in experimental mice to humans. Research in humans, however, for ethical and practical reasons, is largely restricted to in vitro assays that lack components and the complexity of a living organism. To nevertheless study the human hematopoietic and immune system in vivo, xenotransplantation assays have been developed that substitute human components to small animals. Here, we summarize our recent findings that transplantation of human cord blood CD34(+) cells to newborn Rag2(-/-)gamma(c)(-/-) mice leads to de novo development of major functional components of the human adaptive immune system. These human adaptive immune system Rag2(-/-)gamma(c)(-/-) (huAIS-RG) mice can now be used as a technically straightforward preclinical model to evaluate in vivo human adaptive immune system development as well as immune responses, for example, to vaccines or live infectious pathogens.

  14. Genetics, systems, and alcohol.

    PubMed

    McClearn, G E

    1993-03-01

    Under a variety of rubrics (e.g., complexity, self-constructing systems, dissipative structures), interest has recently burgeoned in applying principles of complex systems to a wide variety of scientific issues. A major concern is with emergent properties of systems not derivable from the properties of components of the systems. In this paper, some elementary aspects of "systems" considerations are applied to phenomena of alcohol pharmacogenetics. It is likely that whole new families of informative phenotypes can be generated by this approach.

  15. Quantitative method to assess caries via fluorescence imaging from the perspective of autofluorescence spectral analysis

    NASA Astrophysics Data System (ADS)

    Chen, Q. G.; Zhu, H. H.; Xu, Y.; Lin, B.; Chen, H.

    2015-08-01

    A quantitative method to discriminate caries lesions for a fluorescence imaging system is proposed in this paper. The autofluorescence spectral investigation of 39 teeth samples classified by the International Caries Detection and Assessment System levels was performed at 405 nm excitation. The major differences in the different caries lesions focused on the relative spectral intensity range of 565-750 nm. The spectral parameter, defined as the ratio of wavebands at 565-750 nm to the whole spectral range, was calculated. The image component ratio R/(G + B) of color components was statistically computed by considering the spectral parameters (e.g. autofluorescence, optical filter, and spectral sensitivity) in our fluorescence color imaging system. Results showed that the spectral parameter and image component ratio presented a linear relation. Therefore, the image component ratio was graded as <0.66, 0.66-1.06, 1.06-1.62, and >1.62 to quantitatively classify sound, early decay, established decay, and severe decay tissues, respectively. Finally, the fluorescence images of caries were experimentally obtained, and the corresponding image component ratio distribution was compared with the classification result. A method to determine the numerical grades of caries using a fluorescence imaging system was proposed. This method can be applied to similar imaging systems.

  16. Stellar populations, stellar masses and the formation of galaxy bulges and discs at z < 3 in CANDELS

    NASA Astrophysics Data System (ADS)

    Margalef-Bentabol, Berta; Conselice, Christopher J.; Mortlock, Alice; Hartley, Will; Duncan, Kenneth; Kennedy, Rebecca; Kocevski, Dale D.; Hasinger, Guenther

    2018-02-01

    We present a multicomponent structural analysis of the internal structure of 1074 high-redshift massive galaxies at 1 < z < 3 from the CANDELS HST Survey. In particular, we examine galaxies best fitted by two structural components, and thus likely forming discs and bulges. We examine the stellar mass, star formation rates (SFRs) and colours of both the inner 'bulge' and outer 'disc' components for these systems using Spectral Energy Distribution (SED) information from the resolved ACS+WFC3 HST imaging. We find that the majority of both inner and outer components lie in the star-forming region of UVJ space (68 and 90 per cent, respectively). However, the inner portions, or the likely forming bulges, are dominated by dusty star formation. Furthermore, we show that the outer components of these systems have a higher SFR than their inner regions, and the ratio of SFR between 'disc' and 'bulge' increases at lower redshifts. Despite the higher SFR of the outer component, the stellar mass ratio of inner to outer component remains constant through this epoch. This suggests that there is mass transfer from the outer to inner components for typical two-component-forming systems, thus building bulges from discs. Finally, using Chandra data we find that the presence of an active galactic nucleus is more common in both one-component spheroid-like galaxies and two-component systems (13 ± 3 and 11 ± 2 per cent) than in one-component disc-like galaxies (3 ± 1 per cent), demonstrating that the formation of a central inner component likely triggers the formation of central massive black holes in these galaxies.

  17. The DOE ETV-1 Electric Test Vehicle. Phase 3: Performance Testing and system evaluation

    NASA Technical Reports Server (NTRS)

    Kurtz, D.

    1981-01-01

    Engineering tests were conducted in order to characterize overall system performance and component efficiencies within the system environment. A dynamometer was used in order to minimize the ambient effects and large uncertainties present in track testing. Extensive test requirements were defined and procedures were carefully controlled in order to maintain a high degree of credibility. Limited track testing was performed in order to corroborate the dynamometer results. Test results include an energy flow analysis through the major subsystems and incorporate the aerodynamic and rolling losses under cyclic and various steady speed conditions. The major output from all relevant dynamometer and track tests is also included.

  18. Controlled Ecological Life Support System Breadboard Project - 1988

    NASA Technical Reports Server (NTRS)

    Knott, W. M.

    1989-01-01

    The Controlled Ecological Life Support System (CELSS) Breadboard Project, NASA's effort to develop the technology required to produce a functioning bioregenerative system, is discussed. The different phases of the project and its current status are described. The relationship between the project components are shown, and major project activities for fiscal years 1989-1993 are listed. The biomass production chamber to be used by the project is described.

  19. Comparison of LISP and MUMPS as implementation languages for knowledge-based systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Curtis, A.C.

    1984-01-01

    Major components of knowledge-based systems are summarized, along with the programming language features generally useful in their implementation. LISP and MUMPS are briefly described and compared as vehicles for building knowledge-based systems. The paper concludes with suggestions for extensions to MUMPS which might increase its usefulness in artificial intelligence applications without affecting the essential nature of the language. 8 references.

  20. Potential structural material problems in a hydrogen energy system

    NASA Technical Reports Server (NTRS)

    Gray, H. R.; Nelson, H. G.; Johnson, R. E.; Mcpherson, B.; Howard, F. S.; Swisher, J. H.

    1975-01-01

    Potential structural material problems that may be encountered in the three components of a hydrogen energy system - production, transmission/storage, and utilization - were identified. Hydrogen embrittlement, corrosion, oxidation, and erosion may occur during the production of hydrogen. Hydrogen embrittlement is of major concern during both transmission and utilization of hydrogen. Specific materials research and development programs necessary to support a hydrogen energy system are described.

  1. Flexible manufacturing of aircraft engine parts

    NASA Astrophysics Data System (ADS)

    Hassan, Ossama M.; Jenkins, Douglas M.

    1992-06-01

    GE Aircraft Engines, a major supplier of jet engines for commercial and military aircraft, has developed a fully integrated manufacturing facility to produce aircraft engine components in flexible manufacturing cells. This paper discusses many aspects of the implementation including process technologies, material handling, software control system architecture, socio-technical systems and lessons learned. Emphasis is placed on the appropriate use of automation in a flexible manufacturing system.

  2. Development of Cryogenic Engine for GSLV MkIII: Technological Challenges

    NASA Astrophysics Data System (ADS)

    Praveen, RS; Jayan, N.; Bijukumar, KS; Jayaprakash, J.; Narayanan, V.; Ayyappan, G.

    2017-02-01

    Cryogenic engine capable of delivering 200 kN thrust is being developed for the first time in the country by ISRO for powering the upper stage of GSLV Mk-III, the next generation launch vehicle of ISRO capable of launching four tonne class satellites to Geo-synchronous Transfer Orbit(GTO). Development of this engine started a decade ago when various sub-systems development and testing were taken up. Starting with injector element development, the design, realization and testing of the major sub-systems viz the gas generator, turbopumps, start-up system and thrust chamber have been successfully done in a phased manner before conducting a series of developmental tests in the integrated engine mode. Apart from the major sub-systems, many critical components like the igniter, control components etc were independently developed and qualified. During the development program many challenges were faced in almost all areas of propulsion engineering. Systems engineering of the engine was another key challenge in the realization. This paper gives an outlook on various technological challenges faced in the key areas related to the engine development, insight to the solutions and measures taken to overcome the challenges.

  3. Overview of past, ongoing and future efforts of the integrated modeling of global change for Northern Eurasia

    NASA Astrophysics Data System (ADS)

    Monier, Erwan; Kicklighter, David; Sokolov, Andrei; Zhuang, Qianlai; Melillo, Jerry; Reilly, John

    2016-04-01

    Northern Eurasia is both a major player in the global carbon budget (it includes roughly 70% of the Earth's boreal forest and more than two-thirds of the Earth's permafrost) and a region that has experienced dramatic climate change (increase in temperature, growing season length, floods and droughts) over the past century. Northern Eurasia has also undergone significant land-use change, both driven by human activity (including deforestation, expansion of agricultural lands and urbanization) and natural disturbances (such as wildfires and insect outbreaks). These large environmental and socioeconomic impacts have major implications for the carbon cycle in the region. Northern Eurasia is made up of a diverse set of ecosystems that range from tundra to forests, with significant areas of croplands and pastures as well as deserts, with major urban areas. As such, it represents a complex system with substantial challenges for the modeling community. In this presentation, we provide an overview of past, ongoing and possible future efforts of the integrated modeling of global change for Northern Eurasia. We review the variety of existing modeling approaches to investigate specific components of Earth system dynamics in the region. While there are a limited number of studies that try to integrate various aspects of the Earth system (through scale, teleconnections or processes), we point out that there are few systematic analyses of the various feedbacks within the Earth system (between components, regions or scale). As a result, there is a lack of knowledge of the relative importance of such feedbacks, and it is unclear how policy relevant current studies are that fail to account for these feedbacks. We review the role of Earth system models, and their advantages/limitations compared to detailed single component models. We further introduce the human activity system (global trade, economic models, demographic model and so on), the need for coupled human/earth system models and Integrated Assessment Models (IAMs), a suite of models that couple human activity models to Earth System Models. Finally, we conclude the presentation with examples of emerging issues that require a representation of the coupled human/earth system models.

  4. Microsatellites in the Eukaryotic DNA Mismatch Repair Genes as Modulators of Evolutionary Mutation Rate

    NASA Technical Reports Server (NTRS)

    Chang, Dong Kyung; Metzgar, David; Wills, Christopher; Boland, C. Richard

    2003-01-01

    All "minor" components of the human DNA mismatch repair (MMR) system-MSH3, MSH6, PMS2, and the recently discovered MLH3-contain mononucleotide microsatellites in their coding sequences. This intriguing finding contrasts with the situation found in the major components of the DNA MMR system-MSH2 and MLH1-and, in fact, most human genes. Although eukaryotic genomes are rich in microsatellites, non-triplet microsatellites are rare in coding regions. The recurring presence of exonal mononucleotide repeat sequences within a single family of human genes would therefore be considered exceptional.

  5. Implementation Status of Accrual Accounting System in Health Sector

    PubMed Central

    Mehrolhassani, Mohammad Hossien; Khayatzadeh-Mahani, Akram; Emami, Mozhgan

    2015-01-01

    Introduction: Management of financial resources in health systems is one of the major issues of concern for policy makers globally. As a sub-set of financial management, accounting system is of paramount importance. In this paper, which presents part of the results of a wider research project on transition process from a cash accounting system to an accrual accounting system, we look at the impact of components of change on implementation of the new system. Implementing changes is fraught with many obstacles and surveying these challenges will help policy makers to better overcome them. Methods: The study applied a quantitative manner in 2012 at Kerman University of Medical Science in Iran. For the evaluation, a teacher made valid questionnaire with Likert scale was used (Cranach’s alpha of 0.89) which included 7 change components in accounting system. The study population was 32 subordinate units of Kerman University of Medical Sciences and for data analysis, descriptive and inferential statistics and correlation coefficient in SPSS version 19 were used. Results: Level of effect of all components on the implementation was average downward (5.06±1.86), except for the component “management & leadership (3.46±2.25)” (undesirable from external evaluators’ viewpoint) and “technology (6.61±1.92) and work processes (6.35±2.19)” (middle to high from internal evaluators’ viewpoint). Conclusions: Results showed that the establishment of accrual accounting system faces infrastructural challenges, especially the components of leadership and management and followers. As such, developing effective measures to overcome implementation obstacles should target these components. PMID:25560337

  6. Port performance freight statistics program annual report to Congress, 2016.

    DOT National Transportation Integrated Search

    2017-01-01

    Maritime ports are a major component of the Nations freight transportation system. : Collectively they handle 75 percent of Americas international trade by volume. : 1 Port : throughput (the typical amount of cargo a port handles annually) and ...

  7. Implications of Aggregated DoD Information Systems for Information Assurance Certification and Accreditation

    DTIC Science & Technology

    2010-01-01

    offshoring, or producing major software components overseas (Defense Science Board, 2009). These trends raise concerns about the level of trust that...7 Software Complexity...7 Increasing Software Vulnerabilities and Malware Population . . . . . . . . . . . . . . . . 9 Limitations of

  8. A system-level view of optimizing high-channel-count wireless biosignal telemetry.

    PubMed

    Chandler, Rodney J; Gibson, Sarah; Karkare, Vaibhav; Farshchi, Shahin; Marković, Dejan; Judy, Jack W

    2009-01-01

    In this paper we perform a system-level analysis of a wireless biosignal telemetry system. We perform an analysis of each major system component (e.g., analog front end, analog-to-digital converter, digital signal processor, and wireless link), in which we consider physical, algorithmic, and design limitations. Since there are a wide range applications for wireless biosignal telemetry systems, each with their own unique set of requirements for key parameters (e.g., channel count, power dissipation, noise level, number of bits, etc.), our analysis is equally broad. The net result is a set of plots, in which the power dissipation for each component and as the system as a whole, are plotted as a function of the number of channels for different architectural strategies. These results are also compared to existing implementations of complete wireless biosignal telemetry systems.

  9. Cyber Security Assessment Report: Adventium Labs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2007-12-31

    Major control system components often have life spans of 15-20 years. Many systems in our Nation's critical infrastructure were installed before the Internet became a reality and security was a concern. Consequently, control systems are generally insecure. Security is now being included in the development of new control system devices; however, legacy control systems remain vulnerable. Most efforts to secure control systems are aimed at protecting network borers, but if an intruder gets inside the network these systems are vulnerable to a cyber attack.

  10. An Integrated High Resolution Hydrometeorological Modeling Testbed using LIS and WRF

    NASA Technical Reports Server (NTRS)

    Kumar, Sujay V.; Peters-Lidard, Christa D.; Eastman, Joseph L.; Tao, Wei-Kuo

    2007-01-01

    Scientists have made great strides in modeling physical processes that represent various weather and climate phenomena. Many modeling systems that represent the major earth system components (the atmosphere, land surface, and ocean) have been developed over the years. However, developing advanced Earth system applications that integrates these independently developed modeling systems have remained a daunting task due to limitations in computer hardware and software. Recently, efforts such as the Earth System Modeling Ramework (ESMF) and Assistance for Land Modeling Activities (ALMA) have focused on developing standards, guidelines, and computational support for coupling earth system model components. In this article, the development of a coupled land-atmosphere hydrometeorological modeling system that adopts these community interoperability standards, is described. The land component is represented by the Land Information System (LIS), developed by scientists at the NASA Goddard Space Flight Center. The Weather Research and Forecasting (WRF) model, a mesoscale numerical weather prediction system, is used as the atmospheric component. LIS includes several community land surface models that can be executed at spatial scales as fine as 1km. The data management capabilities in LIS enable the direct use of high resolution satellite and observation data for modeling. Similarly, WRF includes several parameterizations and schemes for modeling radiation, microphysics, PBL and other processes. Thus the integrated LIS-WRF system facilitates several multi-model studies of land-atmosphere coupling that can be used to advance earth system studies.

  11. Legume Information System (LegumeInfo.org): a key component of a set of federated data resources for the legume family

    USDA-ARS?s Scientific Manuscript database

    The Legume Information System (LIS), at http://legumeinfo.org, is a genomic data portal (GDP) for the legume family. LIS provides access to genetic and genomic information for major crop and model legumes. With more than two-dozen domesticated legume species, there are numerous specialists working o...

  12. Swatch Testing at Elevated Wind Speeds

    DTIC Science & Technology

    2014-07-17

    closures, for improved system performance. 15. SUBJECT TERMS Swatch Testing; Individual Protective Equipment (IPE) 16. SECURITY CLASSIFICATION...new wind tunnel swatch technique allows the systematic testing IPE components, such as fasteners, seams, and closures, for improved system...protective overgarment) achieve this isolation by sealing users in a chemically impermeable garment . Heat stress becomes a major problem with this

  13. Optical memory development. Volume 1: prototype memory system

    NASA Technical Reports Server (NTRS)

    Cosentino, L. S.; Mezrich, R. S.; Nagle, E. M.; Stewart, W. C.; Wendt, F. S.

    1972-01-01

    The design, development, and implementation of a prototype, partially populated, million bit read-write holographic memory system using state-of-the-art components are described. The system employs an argon ion laser, acoustooptic beam deflectors, a holographic beam splitter (hololens), a nematic liquid crystal page composer, a photoconductor-thermoplastic erasable storage medium, a silicon P-I-N photodiode array, with lenses and electronics of both conventional and custom design. Operation of the prototype memory system was successfully demonstrated. Careful attention is given to the analysis from which the design criteria were developed. Specifications for the major components are listed, along with the details of their construction and performance. The primary conclusion resulting from this program is that the basic principles of read-write holographic memory system are well understood and are reducible to practice.

  14. SNAP-8 electrical generating system development program

    NASA Technical Reports Server (NTRS)

    1971-01-01

    The SNAP-8 program has developed the technology base for one class of multikilowatt dynamic space power systems. Electrical power is generated by a turbine-alternator in a mercury Rankine-cycle loop to which heat is transferred and removed by means of sodium-potassium eutectic alloy subsystems. Final system overall criteria include a five-year operating life, restartability, man rating, and deliverable power in the 90 kWe range. The basic technology was demonstrated by more than 400,000 hours of major component endurance testing and numerous startup and shutdown cycles. A test system, comprised of developed components, delivered up to 35 kWe for a period exceeding 12,000 hours. The SNAP-8 system baseline is considered to have achieved a level of technology suitable for final application development for long-term multikilowatt space missions.

  15. Preliminary Investigation of Wastewater-Related Contaminants Near Home Sewage Treatment Systems in Ohio

    DTIC Science & Technology

    2005-01-01

    preservative, component of tar, diesel, or crude oil, CP Anthraquinone 0.5 Manuf dye/ textiles , seed treatment, bird repellant Benzo[a]pyrene 0.5...diethyl-meta-toluamide (Deet) 0.5 I, urban uses, mosquito repellent Naphthalene 0.5 Fumigant, moth repellent , major component (about 10%) of...UV, ultraviolet; --, no data] Compound name Laboratory reporting limit Possible compound uses or sources 1,4-Dichlorobenzene 0.5 Moth repellant

  16. Puncture-proof picture archiving and communication system.

    PubMed

    Willis, C E; McCluggage, C W; Orand, M R; Parker, B R

    2001-06-01

    As we become increasingly dependent on our picture archiving and communications system (PACS) for the clinical practice of medicine, the demand for improved reliability becomes urgent. Borrowing principles from the discipline of Reliability Engineering, we have identified components of our system that constitute single points of failure and have endeavored to eliminate these through redundant components and manual work-around procedures. To assess the adequacy of our preparations, we have identified a set of plausible events that could interfere with the function of one or more of our PACS components. These events could be as simple as the loss of the network connection to a single component or as broad as the loss of our central data center. We have identified the need to continue to operate during adverse conditions, as well as the requirement to recover rapidly from major disruptions in service. This assessment led us to modify the physical locations of central PACS components within our physical plant. We are also taking advantage of actual disruptive events coincident with a major expansion of our facility to test our recovery procedures. Based on our recognition of the vital nature of our electronic images for patient care, we are now recording electronic images in two copies on disparate media. The image database is critical to both continued operations and recovery. Restoration of the database from periodic tape backups with a 24-hour cycle time may not support our clinical scenario: acquisition modalities have a limited local storage capacity, some of which will not contain the daily workload. Restoration of the database from the archived media is an exceedingly slow process, that will likely not meet our requirement to restore clinical operations without significant delay. Our PACS vendor is working on concurrent image databases that would be capable of nearly immediate switchover and recovery.

  17. Comparison of electronic health record system functionalities to support the patient recruitment process in clinical trials.

    PubMed

    Schreiweis, Björn; Trinczek, Benjamin; Köpcke, Felix; Leusch, Thomas; Majeed, Raphael W; Wenk, Joachim; Bergh, Björn; Ohmann, Christian; Röhrig, Rainer; Dugas, Martin; Prokosch, Hans-Ulrich

    2014-11-01

    Reusing data from electronic health records for clinical and translational research and especially for patient recruitment has been tackled in a broader manner since about a decade. Most projects found in the literature however focus on standalone systems and proprietary implementations at one particular institution often for only one singular trial and no generic evaluation of EHR systems for their applicability to support the patient recruitment process does yet exist. Thus we sought to assess whether the current generation of EHR systems in Germany provides modules/tools, which can readily be applied for IT-supported patient recruitment scenarios. We first analysed the EHR portfolio implemented at German University Hospitals and then selected 5 sites with five different EHR implementations covering all major commercial systems applied in German University Hospitals. Further, major functionalities required for patient recruitment support have been defined and the five sample EHRs and their standard tools have been compared to the major functionalities. In our analysis of the site's hospital information system environments (with four commercial EHR systems and one self-developed system) we found that - even though no dedicated module for patient recruitment has been provided - most EHR products comprise generic tools such as workflow engines, querying capabilities, report generators and direct SQL-based database access which can be applied as query modules, screening lists and notification components for patient recruitment support. A major limitation of all current EHR products however is that they provide no dedicated data structures and functionalities for implementing and maintaining a local trial registry. At the five sites with standard EHR tools the typical functionalities of the patient recruitment process could be mostly implemented. However, no EHR component is yet directly dedicated to support research requirements such as patient recruitment. We recommend for future developments that EHR customers and vendors focus much more on the provision of dedicated patient recruitment modules. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  18. A cloud-based approach for interoperable electronic health records (EHRs).

    PubMed

    Bahga, Arshdeep; Madisetti, Vijay K

    2013-09-01

    We present a cloud-based approach for the design of interoperable electronic health record (EHR) systems. Cloud computing environments provide several benefits to all the stakeholders in the healthcare ecosystem (patients, providers, payers, etc.). Lack of data interoperability standards and solutions has been a major obstacle in the exchange of healthcare data between different stakeholders. We propose an EHR system - cloud health information systems technology architecture (CHISTAR) that achieves semantic interoperability through the use of a generic design methodology which uses a reference model that defines a general purpose set of data structures and an archetype model that defines the clinical data attributes. CHISTAR application components are designed using the cloud component model approach that comprises of loosely coupled components that communicate asynchronously. In this paper, we describe the high-level design of CHISTAR and the approaches for semantic interoperability, data integration, and security.

  19. Predictive Ability of the SVS WIfI Classification System following First-time Lower Extremity Revascularizations

    PubMed Central

    Darling, Jeremy D.; McCallum, John C.; Soden, Peter A.; Guzman, Raul J.; Wyers, Mark C.; Hamdan, Allen D.; Verhagen, Hence J.; Schermerhorn, Marc L.

    2017-01-01

    OBJECTIVES The SVS WIfI (wound, ischemia, foot infection) classification system was proposed to predict 1-year amputation risk and potential benefit from revascularization. Our goal was to evaluate the predictive ability of this scale in a “real world” selection of patients undergoing a first time lower extremity revascularization for chronic limb threatening ischemia (CLTI). METHODS From 2005 to 2014, 1,336 limbs underwent a first time lower extremity revascularization for CLTI, of which 992 had sufficient data to classify all three WIfI components (wound, ischemia, and foot infection). Limbs were stratified into the SVS WIfI clinical stages (from 1 to 4) for 1-year amputation risk estimation, as well as a novel WIfI composite score from 0 to 9 (that weighs all WIfI variables equally) and a novel WIfI mean score from 0 to 3 (that can incorporate limbs missing any of the three WIfI components). Outcomes included major amputation, RAS events (revascularization, major amputation, or stenosis [>3.5× step-up by duplex]), and mortality. Predictors were identified using Cox regression models and Kaplan-Meier survival estimates. RESULTS Of the 1,336 first-time procedures performed, 992 limbs were classified in all three WIfI components (524 endovascular, 468 bypass; 26% rest pain, 74% tissue loss). Cox regression demonstrated that a one-unit increase in the WIfI clinical stage increases the risk of major amputation and RAS events in all limbs (Hazard Ratio [HR] 2.4; 95% Confidence Interval [CI] 1.7–3.2 and 1.2 [1.1–1.3], respectively). Separate models of the entire cohort, a bypass only cohort, and an endovascular only cohort showed that a one-unit increase in the WIfI mean score is associated with an increase in the risk of major amputation (all three cohorts; 5.3 [3.6–6.8], 4.1 [2.4–6.9], and 6.6 [3.8–11.6], respectively) and RAS events (all three cohorts; 1.7 [1.4–2.0], 1.9 [1.4–2.6], and 1.4 [1.1–1.9], respectively). The novel WIfI composite and WIfI mean scores were the only consistent predictors of mortality among the three cohorts, with the WIfI mean score proving most strongly predictive in the entire cohort (1.4 [1.1–1.7]), the bypass only cohort (1.5 [1.1–1.9]) and the endovascular only cohort (1.4 [1.0–1.8]). Although the individual WIfI wound component was able to predict mortality among all patients (1.1 [1.0–1.2]) and bypass only patients (1.2 [1.1–1.3]), no other individual WIfI component, nor the WIfI clinical stage, were able to significantly predict mortality among any cohort. CONCLUSION This study supports the ability of the SVS WIfI classification system to predict major amputation; however, the novel WIfI mean and WIfI composite scores predict amputation, RAS events, and mortality more consistently than any other current WIfI scoring system. The WIfI mean score allows inclusion of all limbs, and both novel scoring systems are easier to conceptualize, give equal weight to each WIfI component, and may provide clinicians more effective comparisons in outcomes between patients. PMID:28073665

  20. Summary of International Border Crossings Roundtable Meeting Held in Norfolk, Virginia, June 11, 1993

    DOT National Transportation Integrated Search

    2002-04-01

    This document is an executive summary that describes the National Intelligent Transportation System (ITS) Architecture. This document covers the following major topics: (1) ITS Opportunity - need for the architecture; (2) main components of the Na...

  1. Phase II driver survey report: Volvo intelligent vehicle initiative field operational test

    DOT National Transportation Integrated Search

    2004-10-28

    The United States Department of Transportation (USDOT) established an Intelligent Vehicle Initiative (IVI) as a major component of the Intelligent Transportation System (ITS) program. The intent of the IVI is to improve significantly the safety and e...

  2. DoD Financial Management: Important Steps Underway But Reform Will Require a Long-term Commitment

    DTIC Science & Technology

    2002-06-04

    consolidated financial statements . To date, none of the military services or major DOD components has passed the test of an independent financial audit because of weaknesses in financial management systems, operations, and controls.

  3. Tracer techniques in aeolian research: Approaches, applications, and challenges

    USDA-ARS?s Scientific Manuscript database

    Aeolian processes, the entrainment, transport and deposition of sediments by wind, impacts climate, biogeochemical cycles, food security, environmental quality and human health. Considering the multitude of interactions between aeolian processes and all the major components of the Earth system, ther...

  4. Small, modular, low-cost coal-fired power plants for the international market

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zauderer, B.; Frain, B.; Borck, B.

    1997-12-31

    This paper presents recent operating results of Coal Tech`s second generation, air cooled, slagging coal combustor, and its application to power plants in the 1 to 20 MW range. This 20 MMBtu/hour combustor was installed in a new demonstration plant in Philadelphia, PA in 1995. It contains the combustion components of a 1 MWe coal fired power plant, a 17,500 lb/hour steam boiler, coal storage and feed components, and stack gas cleanup components. The plant`s design incorporates improvements resulting from 2,000 hours of testing between 1987 and 1993 on a first generation, commercial scale, air cooled combustor of equal thermalmore » rating. Since operations began in early 1996, a total of 51 days of testing have been successfully completed. Major results include durability of the combustor`s refractory wall, excellent combustion with high ash concentration in the fuel, removal of 95% to 100% of the slag in the combustor, very little ash deposition in the boiler, major reduction of in-plant parasitic power, and simplified power system control through the use of modular designs of sub-systems and computer control. Rapid fuel switching between oil, gas, and coal and turndown of up to a factor of three was accomplished. All these features have been incorporated in advanced coal fired plant designs in the 1 to 20 MWe range. Incremental capital costs are only $100 to $200/kW higher than comparable rated gas or oil fired steam generating systems. Most of its components and subsystems can be factory assembled for very rapid field installation. The low capital, low operating costs, fuel flexibility, and compatibility with very high ash fuels, make this power system very attractive in regions of the world having domestic supplies of these fuels.« less

  5. Online damage inspection of optics for ATP system

    NASA Astrophysics Data System (ADS)

    Chen, Jing; Jiang, Yu; Mao, Yao; Gan, Xun; Liu, Qiong

    2016-09-01

    In the Electro-Optical acquisition-tracking-pointing system (ATP), the optical components will be damaged with the several influencing factors. In this situation, the rate will increase sharply when the arrival of damage to some extent. As the complex processing techniques and long processing cycle of optical components, the damage will cause the great increase of the system development cost and cycle. Therefore, it is significant to detect the laser-induced damage in the ATP system. At present, the major research on the on-line damage detection technology of optical components is for the large optical system in the international. The relevant detection systems have complicated structures and many of components, and require enough installation space reserved, which do not apply for ATP system. To solve the problem mentioned before, This paper use a method based on machine vision to detect the damage on-line for the present ATP system. To start with, CCD and PC are used for image acquisition. Secondly, smoothing filters are used to restrain false damage points produced by noise. Then, with the shape feature included in the damage image, the OTSU Method which can define the best segmentation threshold automatically is used to achieve the goal to locate the damage regions. At last, we can supply some opinions for the lifetime of the optical components by analyzing the damage data, such as damage area, damage position. The method has the characteristics of few-detectors and simple-structures which can be installed without any changes of the original light path. With the method, experimental results show that it is stable and effective to achieve the goal of detecting the damage of optical components on-line in the ATP system.

  6. International Space Station Major Constituent Analyzer On-Orbit Performance

    NASA Technical Reports Server (NTRS)

    Gardner, Ben D.; Erwin, Phillip M.; Cougar, Tamara; Ulrich, BettyLynn

    2017-01-01

    The Major Constituent Analyzer (MCA) is a mass spectrometer based system that measures the major atmospheric constituents on the International Space Station. A number of limited-life components require periodic change-out, including the ORU 02 analyzer and the ORU 08 Verification Gas Assembly. The most recent ORU 02 and ORU 08 assemblies in the LAB MCA are operating nominally. For ORU 02, the ion source filaments and ion pump lifetime continue to be key determinants of MCA performance. Finally, the Node 3 MCA is being brought to an operational configuration.

  7. An analysis of the technical status of high level radioactive waste and spent fuel management systems

    NASA Technical Reports Server (NTRS)

    English, T.; Miller, C.; Bullard, E.; Campbell, R.; Chockie, A.; Divita, E.; Douthitt, C.; Edelson, E.; Lees, L.

    1977-01-01

    The technical status of the old U.S. mailine program for high level radioactive nuclear waste management, and the newly-developing program for disposal of unreprocessed spent fuel was assessed. The method of long term containment for both of these waste forms is considered to be deep geologic isolation in bedded salt. Each major component of both waste management systems is analyzed in terms of its scientific feasibility, technical achievability and engineering achievability. The resulting matrix leads to a systematic identification of major unresolved technical or scientific questions and/or gaps in these programs.

  8. Development of a Dynamically Configurable,Object-Oriented Framework for Distributed, Multi-modal Computational Aerospace Systems Simulation

    NASA Technical Reports Server (NTRS)

    Afjeh, Abdollah A.; Reed, John A.

    2003-01-01

    This research is aimed at developing a neiv and advanced simulation framework that will significantly improve the overall efficiency of aerospace systems design and development. This objective will be accomplished through an innovative integration of object-oriented and Web-based technologies ivith both new and proven simulation methodologies. The basic approach involves Ihree major areas of research: Aerospace system and component representation using a hierarchical object-oriented component model which enables the use of multimodels and enforces component interoperability. Collaborative software environment that streamlines the process of developing, sharing and integrating aerospace design and analysis models. . Development of a distributed infrastructure which enables Web-based exchange of models to simplify the collaborative design process, and to support computationally intensive aerospace design and analysis processes. Research for the first year dealt with the design of the basic architecture and supporting infrastructure, an initial implementation of that design, and a demonstration of its application to an example aircraft engine system simulation.

  9. Simulating advanced life support systems to test integrated control approaches

    NASA Astrophysics Data System (ADS)

    Kortenkamp, D.; Bell, S.

    Simulations allow for testing of life support control approaches before hardware is designed and built. Simulations also allow for the safe exploration of alternative control strategies during life support operation. As such, they are an important component of any life support research program and testbed. This paper describes a specific advanced life support simulation being created at NASA Johnson Space Center. It is a discrete-event simulation that is dynamic and stochastic. It simulates all major components of an advanced life support system, including crew (with variable ages, weights and genders), biomass production (with scalable plantings of ten different crops), water recovery, air revitalization, food processing, solid waste recycling and energy production. Each component is modeled as a producer of certain resources and a consumer of certain resources. The control system must monitor (via sensors) and control (via actuators) the flow of resources throughout the system to provide life support functionality. The simulation is written in an object-oriented paradigm that makes it portable, extensible and reconfigurable.

  10. Solute Response To Arid-Climate Managed-River Flow During Storm Events

    NASA Astrophysics Data System (ADS)

    McLean, B.; Shock, E.

    2006-12-01

    Storm pulses are widely used in unmanaged, temperate and subtropical river systems to resolve in-stream surface and subsurface flow components. Resulting catchment-scale hydrochemical mixing models yield insight into mechanisms of solute transport. Managed systems are far more complicated due to the human need for high quality water resources, which drives processes that are superimposed on most, if not all, of the unmanaged components. As an example, an increasingly large portion of the water supply for the Phoenix metropolitan area is derived from multiple surface water sources that are impounded, diverted and otherwise managed upstream from the urban core that consumes the water and produces anthropogenic impacts. During large storm events this managed system is perturbed towards natural behavior as it receives inputs from natural hydrologic pathways in addition to impervious surfaces and storm water drainage channels. Our goals in studying managed river systems during this critical transition state are to determine how the well- characterized behavior of natural systems break down as the system responds then returns to its managed state. Using storm events as perturbations we can contrast an arid managed system with the unmanaged system it approaches during the storm event. In the process, we can extract geochemical consequences specifically related to unknown urban components in the form of chemical fingerprints. The effects of river management on solute behavior were assessed by taking advantage of several anomalously heavy winter storm events in late 2004 and early 2005 using a rigorous sampling routine. Several hundred samples collected between January and October 2005 were analyzed for major ion, isotopic, and trace metal concentrations with 78 individual measurements for each sample. The data are used to resolve managed watershed processes, mechanisms of solute transport and river mixing from anthropogenic inputs. Our results show that concentrations of major solutes change slowly and are independent of discharge downstream from the dams on two major tributaries. This is indicative of reservoir release water. In addition, a third input is derived from the Colorado River via the Central Arizona Project canal system. Cross plots including concentrations of solutes such as nitrate and sulfate from downstream of the confluence indicate at least three end-member sources, as do Piper diagrams using major anion and cation data. Dynamic contributions from natural event water and urban inputs can be resolved from the slowly changing release water, and may dictate the short-term transport of pollutants during the storm-induced transition state.

  11. Concepts for on-board satellite image registration. Volume 3: Impact of VLSI/VHSIC on satellite on-board signal processing

    NASA Technical Reports Server (NTRS)

    Aanstoos, J. V.; Snyder, W. E.

    1981-01-01

    Anticipated major advances in integrated circuit technology in the near future are described as well as their impact on satellite onboard signal processing systems. Dramatic improvements in chip density, speed, power consumption, and system reliability are expected from very large scale integration. Improvements are expected from very large scale integration enable more intelligence to be placed on remote sensing platforms in space, meeting the goals of NASA's information adaptive system concept, a major component of the NASA End-to-End Data System program. A forecast of VLSI technological advances is presented, including a description of the Defense Department's very high speed integrated circuit program, a seven-year research and development effort.

  12. [Evolution of the audio-visual technologies of production and diffusion and the conditions of their application in the Third World].

    PubMed

    Lefebvre, M

    1979-01-01

    The present information production techniques are so inefficient that it is out of the question to generalize them. On the other hand audio-visual communication raises a major political problem, especially for developing countries. Audio-visual equipment has gone through adjustment phases; the example of the tape and cassette recorder is given: 2 technological improvements have completely modified its use; the transistors have allowed considerable reduction in volume and weight as well as the energy necessary; the invention of the cassette has simplified its use. Technological research is following 3 major directions: the production of equipment which consumes little energy; the improvement of electronic component production techniques (towards cheaper electronic components); finally, the designing of systems allowing to stock large quantities of information. The communication systems will probably make so much progress in the areas of technology and programming, that they will soon have very different uses than the present ones. The question is whether our civilizations will let themselves be dominated by these new systems, or whether they will succeed to turn them into progress tools.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Finnerty, W.R.

    We have sought the structural elucidation of the glycolipid biosurfactant. The extracellular glycolipid consists of 1 major component (>90%) plus 6--7 minor molecular species. The deacylated water-soluble backbone is common to all molecular species of the glycolipid. A complex fatty acid composition characterizes the glycolipid and contributes to its surface active character. The water soluble backbone consists of glycerol, trehalose and 3--5 glucose residues. FTIR spectroscopy has confirmed the presence of these polyhydric components. The next major objective has been to clone the genes for glycolipid biosynthesis in Rhodococcus sp. H13-A. Improvements in the E. coli-Rhodococcus shuttle vector, pMVS301, weremore » made prior to the construction and screening of a genomic library in Rhodococcus. A system is being developed for transpositional mutagenesis in Rhodococcus, using Tn917 containing plasmids used successfully in Bacillus sp. for the isolation and analysis of sporulation and developmental genes. We are also actively assessing the utility of this cloning and transformation system which we have developed for Rhodococcus, for use in mycobacterium, a related Actinomycete for which there exists no systems for plasmid transformation or molecular cloning. 8 refs., 1 fig.« less

  14. Appendix A: Proposed statement of work, 1994

    NASA Technical Reports Server (NTRS)

    1993-01-01

    This NRA effort is devoted to developing new techniques and methodologies which utilize and/or provide support to Integrated Vehicle Health Management (IVHM) concepts and techniques, modern design processes, and open architectures to realize an avionics system architecture that relieves the flight control system (FCS) of the requirement of maintaining intimate knowledge and control of the vehicle subsystems (for instance, the reaction control system (RCS)). The benefit of this architecture is that future upgrades and enhancements to the system(s) or to individual components within the system(s) are greatly simplified. This approach also allows a much more straightforward treatment of failure analysis, system diagnosis, and the design of fault containment domains. This NRA effort is also devoted to realizing capabilities to provide an available avionics system (and subsystem(s)) at minimum operational cost. This thrust provides a direct benefit to NASA in that it seeks to accelerate the design cycle to allow state of the art components and designs to actually appear in the fielded system rather than merely in the initial design. To achieve this, this effort is intended to benefit from efforts already underway at Lockheed and other major contractors. For instance, Lockheed Sanders is currently engaged in a major DoD funded development program which has the goal of cutting design cycle time of high performance electronics by a factor of four while simultaneously improving quality also by a factor of four. The early work on this program was used to enable the rapid prototyping of the Reaction Jet Drive Controller which was accomplished in 1993. Similarly, maximum leverage will be derived from recent NASA and DoD efforts to increase the content of high quality commercial grade electronic components in systems for aerospace applications. Both of these goals result in a system with enhanced cost effectiveness, increased reliability, and greatly increased performance compared to a system developed using a more conventional approach.

  15. Appendix A: Proposed statement of work, 1994

    NASA Astrophysics Data System (ADS)

    1993-12-01

    This NRA effort is devoted to developing new techniques and methodologies which utilize and/or provide support to Integrated Vehicle Health Management (IVHM) concepts and techniques, modern design processes, and open architectures to realize an avionics system architecture that relieves the flight control system (FCS) of the requirement of maintaining intimate knowledge and control of the vehicle subsystems (for instance, the reaction control system (RCS)). The benefit of this architecture is that future upgrades and enhancements to the system(s) or to individual components within the system(s) are greatly simplified. This approach also allows a much more straightforward treatment of failure analysis, system diagnosis, and the design of fault containment domains. This NRA effort is also devoted to realizing capabilities to provide an available avionics system (and subsystem(s)) at minimum operational cost. This thrust provides a direct benefit to NASA in that it seeks to accelerate the design cycle to allow state of the art components and designs to actually appear in the fielded system rather than merely in the initial design. To achieve this, this effort is intended to benefit from efforts already underway at Lockheed and other major contractors. For instance, Lockheed Sanders is currently engaged in a major DoD funded development program which has the goal of cutting design cycle time of high performance electronics by a factor of four while simultaneously improving quality also by a factor of four. The early work on this program was used to enable the rapid prototyping of the Reaction Jet Drive Controller which was accomplished in 1993. Similarly, maximum leverage will be derived from recent NASA and DoD efforts to increase the content of high quality commercial grade electronic components in systems for aerospace applications. Both of these goals result in a system with enhanced cost effectiveness, increased reliability, and greatly increased performance compared to a system developed using a more conventional approach.

  16. A Framework and Toolkit for the Construction of Multimodal Learning Interfaces

    DTIC Science & Technology

    1998-04-29

    human communication modalities in the context of a broad class of applications, specifically those that support state manipulation via parameterized actions. The multimodal semantic model is also the basis for a flexible, domain independent, incrementally trainable multimodal interpretation algorithm based on a connectionist network. The second major contribution is an application framework consisting of reusable components and a modular, distributed system architecture. Multimodal application developers can assemble the components in the framework into a new application,

  17. The Intellectual Supermarket.

    ERIC Educational Resources Information Center

    Demb, Ada

    2002-01-01

    Discusses how separating undergraduate education into its two primary components--general education and the major--and then applying the perspective of a supermarket analogy leads to startling conclusions about possible transformations of the production and distribution system for higher education at the undergraduate level and for implementing…

  18. Selecting Appropriate Functionality and Technologies for EPSS.

    ERIC Educational Resources Information Center

    McGraw, Karen L.

    1995-01-01

    Presents background information that describes the major components of an embedded performance support system, compares levels of functionality, and discusses some of the required technologies. Highlights include the human-computer interface; online help; advisors; training and tutoring; hypermedia; and artificial intelligence techniques. (LRW)

  19. Continuous Fiber Ceramic Composite (CFCC) Program: Gaseous Nitridation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    R. Suplinskas G. DiBona; W. Grant

    2001-10-29

    Textron has developed a mature process for the fabrication of continuous fiber ceramic composite (CFCC) tubes for application in the aluminum processing and casting industry. The major milestones in this project are System Composition; Matrix Formulation; Preform Fabrication; Nitridation; Material Characterization; Component Evaluation

  20. Electronic test and calibration circuits, a compilation

    NASA Technical Reports Server (NTRS)

    1972-01-01

    A wide variety of simple test calibration circuits are compiled for the engineer and laboratory technician. The majority of circuits were found inexpensive to assemble. Testing electronic devices and components, instrument and system test, calibration and reference circuits, and simple test procedures are presented.

  1. Low cost attitude control system reaction wheel development

    NASA Astrophysics Data System (ADS)

    Bialke, William

    1991-03-01

    In order to satisfy a growing demand for low cost attitude control systems for small spacecraft, development of a low power and low cost Reaction Wheel Assembly was initiated. The details of the versatile design resulting from this effort are addressed. Tradeoff analyses for each of the major components are included, as well as test data from an engineering prototype of the hardware.

  2. Soil properties differently influence estimates of soil CO2 efflux from three chamber-based measurement systems

    Treesearch

    John R. Butnor; Kurt H. Johnsen; Chris A. Maier

    2005-01-01

    Soil C02 efflux is a major component of net ecosystem productivity (NEP) of forest systems. Combining data from multiple researchers for larger-scale modeling and assessment will only be valid if their methodologies provide directly comparable results. We conducted a series of laboratory and field tests to assess the presence and magnitude of...

  3. Low cost attitude control system reaction wheel development

    NASA Technical Reports Server (NTRS)

    Bialke, William

    1991-01-01

    In order to satisfy a growing demand for low cost attitude control systems for small spacecraft, development of a low power and low cost Reaction Wheel Assembly was initiated. The details of the versatile design resulting from this effort are addressed. Tradeoff analyses for each of the major components are included, as well as test data from an engineering prototype of the hardware.

  4. A Survey of Electronics Obsolescence and Reliability

    DTIC Science & Technology

    2010-07-01

    properties but there are many minor and major variations (e.g. curing schedule) affecting their usage in packaging processes and in reworking. Curing...within them. Electronic obsolescence is increasingly associated with physical characteristics that reduce component and system reliability, both in usage ...semiconductor technologies and of electronic systems, both in usage and in storage. By design, electronics technologies include few reliability margins

  5. Integrated source and channel encoded digital communication system design study

    NASA Technical Reports Server (NTRS)

    Huth, G. K.; Trumpis, B. D.; Udalov, S.

    1975-01-01

    Various aspects of space shuttle communication systems were studied. The following major areas were investigated: burst error correction for shuttle command channels; performance optimization and design considerations for Costas receivers with and without bandpass limiting; experimental techniques for measuring low level spectral components of microwave signals; and potential modulation and coding techniques for the Ku-band return link. Results are presented.

  6. Projects in an expert system class

    NASA Technical Reports Server (NTRS)

    Whitson, George M.

    1991-01-01

    Many universities now teach courses in expert systems. In these courses students study the architecture of an expert system, knowledge acquisition techniques, methods of implementing systems and verification and validation techniques. A major component of any such course is a class project consisting of the design and implementation of an expert system. Discussed here are a number of techniques that we have used at the University of Texas at Tyler to develop meaningful projects that could be completed in a semester course.

  7. SAGA: A project to automate the management of software production systems

    NASA Technical Reports Server (NTRS)

    Campbell, R. H.; Badger, W.; Beckman, C. S.; Beshers, G.; Hammerslag, D.; Kimball, J.; Kirslis, P. A.; Render, H.; Richards, P.; Terwilliger, R.

    1984-01-01

    The project to automate the management of software production systems is described. The SAGA system is a software environment that is designed to support most of the software development activities that occur in a software lifecycle. The system can be configured to support specific software development applications using given programming languages, tools, and methodologies. Meta-tools are provided to ease configuration. Several major components of the SAGA system are completed to prototype form. The construction methods are described.

  8. Solar energy heating system design package for a single-family residence at New Castle, Pennsylvania

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The design of a solar heating and hot water system for a single family dwelling is described. Cost trade studies on the energy conservation and architectural features of the solar house are discussed. The present status of verification for the single family heating system, i.e., proof that the components and the system meet applicable physical and functional requirements, is reported. The system integration drawings, the major subsystems drawings, and the architect's specifications and plans are included.

  9. 41 CFR 102-85.40 - What are the major components of the pricing policy?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... components of the pricing policy? 102-85.40 Section 102-85.40 Public Contracts and Property Management...-PRICING POLICY FOR OCCUPANCY IN GSA SPACE Pricing Policy-General § 102-85.40 What are the major components of the pricing policy? The major components of the pricing policy are: (a) An OA between a customer...

  10. System for the Management of Trauma and Emergency Surgery in Space

    NASA Technical Reports Server (NTRS)

    Houtchens, B.

    1984-01-01

    The need to develop a systems approach to the management of trauma and other major clinical medical events in space along with appropriate development and evaluation of surgical techniques and required hardware was investigated. A prototype zero gravity surgical module was constructed and tested aboard a KC-135 aircraft during parabolic arc zero G flight. To insure parity of quality care to that available on Earth, it was recommended that a clinical medical and bioengineering advisory committee define and help develop the necessary components of the clinical medical care system for the space station and lunar base. Key components of the system are aerospace surgical training, medical equipment development, including support hardware and software, rapid access to a network of specialty expertise, and continued research and development.

  11. Nambe Pueblo Water Budget and Forecasting model.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brainard, James Robert

    2009-10-01

    This report documents The Nambe Pueblo Water Budget and Water Forecasting model. The model has been constructed using Powersim Studio (PS), a software package designed to investigate complex systems where flows and accumulations are central to the system. Here PS has been used as a platform for modeling various aspects of Nambe Pueblo's current and future water use. The model contains three major components, the Water Forecast Component, Irrigation Scheduling Component, and the Reservoir Model Component. In each of the components, the user can change variables to investigate the impacts of water management scenarios on future water use. The Watermore » Forecast Component includes forecasting for industrial, commercial, and livestock use. Domestic demand is also forecasted based on user specified current population, population growth rates, and per capita water consumption. Irrigation efficiencies are quantified in the Irrigated Agriculture component using critical information concerning diversion rates, acreages, ditch dimensions and seepage rates. Results from this section are used in the Water Demand Forecast, Irrigation Scheduling, and the Reservoir Model components. The Reservoir Component contains two sections, (1) Storage and Inflow Accumulations by Categories and (2) Release, Diversion and Shortages. Results from both sections are derived from the calibrated Nambe Reservoir model where historic, pre-dam or above dam USGS stream flow data is fed into the model and releases are calculated.« less

  12. SNAP-8 electrical generating system development program

    NASA Technical Reports Server (NTRS)

    1971-01-01

    The SNAP-8 program has developed the technology base for one class of multikilowatt dynamic space power systems. Electrical power is generated by a turbine-alternator in a mercury Rankine-cycle loop to which heat is transferred and removed by means of sodium-potassium eutectic alloy subsystems. Final system overall criteria include a five-year operating life, restartability, man rating, and deliverable power in the 90 kWe range. The basic technology has been demonstrated by more than 400,000 hours of major component endurance testing and numerous startup and shutdown cycles. A test system, comprised of developed components, delivered up to 35 kWe for a period exceeding 12,000 hours. The SNAP-8 system baseline is considered to have achieved a level of technology suitable for final application development for long-term multikilowatt space missions.

  13. Installation guidelines for solar heating system, single-family residence at New Castle, Pennsylvania

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The solar heating system installer guidelines are presented for each subsystem. This single family residential heating system is a solar-assisted, hydronic-to-warm-air system with solar-assisted domestic water heating. It is composed of the following major components: (1) liquid cooled flat plate collectors; (2) water storage tank; (3) passive solar-fired domestic water preheater; (4) electric hot water heater; (5) heat pump with electric backup; (6) solar hot water coil unit; (7) tube-and-shell heat exchanger, three pumps, and associated pipes and valving in an energy transport module; (8) control system; and (9) air-cooled heat purge unit. Information is provided on the operating procedures, controls, caution requirements, and routine and schedule maintenance in the form of written descriptions, schematics, detail drawings, pictures, and manufacturer's component data.

  14. PCSYS: The optimal design integration system picture drawing system with hidden line algorithm capability for aerospace vehicle configurations

    NASA Technical Reports Server (NTRS)

    Hague, D. S.; Vanderburg, J. D.

    1977-01-01

    A vehicle geometric definition based upon quadrilateral surface elements to produce realistic pictures of an aerospace vehicle. The PCSYS programs can be used to visually check geometric data input, monitor geometric perturbations, and to visualize the complex spatial inter-relationships between the internal and external vehicle components. PCSYS has two major component programs. The between program, IMAGE, draws a complex aerospace vehicle pictorial representation based on either an approximate but rapid hidden line algorithm or without any hidden line algorithm. The second program, HIDDEN, draws a vehicle representation using an accurate but time consuming hidden line algorithm.

  15. Applied Research Study

    NASA Technical Reports Server (NTRS)

    Leach, Ronald J.

    1997-01-01

    The purpose of this project was to study the feasibility of reusing major components of a software system that had been used to control the operations of a spacecraft launched in the 1980s. The study was done in the context of a ground data processing system that was to be rehosted from a large mainframe to an inexpensive workstation. The study concluded that a systematic approach using inexpensive tools could aid in the reengineering process by identifying a set of certified reusable components. The study also developed procedures for determining duplicate versions of software, which were created because of inadequate naming conventions. Such procedures reduced reengineering costs by approximately 19.4 percent.

  16. Mass sensitivity studies for an inductively driven railgun

    NASA Astrophysics Data System (ADS)

    Scanlon, J. J., III; Young, A. F.

    1991-01-01

    Those areas which result in substantial system mass reductions for an HPG (homopolar generator) driven EML (electromagnetic launcher) are identified. Sensitivity studies are performed by varying launch mass, peak acceleration, launcher efficiency, inductance gradient, injection velocity, barrel mass per unit length, fuel tankage and pump estimates, and component energy and power densities. Two major contributors to the system mass are the allowed number of shots per barrel versus the number required for the mission, and the barrel length. The effects of component performance parameters, such as friction coefficient, injection velocity, ablation coefficient, rail resistivity, armature voltage, peak acceleration, and inductance gradient on these two areas, are addressed.

  17. Remote health monitoring system for detecting cardiac disorders.

    PubMed

    Bansal, Ayush; Kumar, Sunil; Bajpai, Anurag; Tiwari, Vijay N; Nayak, Mithun; Venkatesan, Shankar; Narayanan, Rangavittal

    2015-12-01

    Remote health monitoring system with clinical decision support system as a key component could potentially quicken the response of medical specialists to critical health emergencies experienced by their patients. A monitoring system, specifically designed for cardiac care with electrocardiogram (ECG) signal analysis as the core diagnostic technique, could play a vital role in early detection of a wide range of cardiac ailments, from a simple arrhythmia to life threatening conditions such as myocardial infarction. The system that the authors have developed consists of three major components, namely, (a) mobile gateway, deployed on patient's mobile device, that receives 12-lead ECG signals from any ECG sensor, (b) remote server component that hosts algorithms for accurate annotation and analysis of the ECG signal and (c) point of care device of the doctor to receive a diagnostic report from the server based on the analysis of ECG signals. In the present study, their focus has been toward developing a system capable of detecting critical cardiac events well in advance using an advanced remote monitoring system. A system of this kind is expected to have applications ranging from tracking wellness/fitness to detection of symptoms leading to fatal cardiac events.

  18. The POIS (Parkland On-Line Information System) Implementation of the IBM Health Care Support/Patient Care System

    PubMed Central

    Mishelevich, David J.; Hudson, Betty G.; Van Slyke, Donald; Mize, Elaine I.; Robinson, Anna L.; Brieden, Helen C.; Atkinson, Jack; Robertson, James

    1980-01-01

    The installation of major components of a comprehensive Hospital Information System (HIS) called POIS, the Parkland On-line Information System, including identified success factors is described for the Dallas County Hospital District (DCHD) known also as the Parkland Memorial Hospital. Installation of the on-line IBM Health Care Support (HCS) Registration and Admissions Packages occurred in 1976 and implementation of the HCS Patient Care System (PCS) began in 1977 which includes on-line support of health care areas such as nursing stations and ancillary areas. The Duke Hospital Information System (DHIS) is marketed as the IBM HCS/Patient Care System (PCS). DCHD was the validation site. POIS has order entry, result reporting and work management components. While most of the patient care components are currently installed for the inpatient service, the Laboratories are being installed for the outpatient and Emergency areas as well. The Clinic Appointment System developed at the University of Michigan is also installed. The HCS family of programs use DL/1 and CICS and were installed in the OS versions, currently running under MVS on an IBM 370/168 Model 3 with 8 megabytes of main memory. ImagesFigure 1-AFigure 1-B

  19. Efficient Ultra-High Speed Communication with Simultaneous Phase and Amplitude Regenerative Sampling (SPARS)

    NASA Astrophysics Data System (ADS)

    Carlowitz, Christian; Girg, Thomas; Ghaleb, Hatem; Du, Xuan-Quang

    2017-09-01

    For ultra-high speed communication systems at high center frequencies above 100 GHz, we propose a disruptive change in system architecture to address major issues regarding amplifier chains with a large number of amplifier stages. They cause a high noise figure and high power consumption when operating close to the frequency limits of the underlying semiconductor technologies. Instead of scaling a classic homodyne transceiver system, we employ repeated amplification in single-stage amplifiers through positive feedback as well as synthesizer-free self-mixing demodulation at the receiver to simplify the system architecture notably. Since the amplitude and phase information for the emerging oscillation is defined by the input signal and the oscillator is only turned on for a very short time, it can be left unstabilized and thus come without a PLL. As soon as gain is no longer the most prominent issue, relaxed requirements for all the other major components allow reconsidering their implementation concepts to achieve further improvements compared to classic systems. This paper provides the first comprehensive overview of all major design aspects that need to be addressed upon realizing a SPARS-based transceiver. At system level, we show how to achieve high data rates and a noise performance comparable to classic systems, backed by scaled demonstrator experiments. Regarding the transmitter, design considerations for efficient quadrature modulation are discussed. For the frontend components that replace PA and LNA amplifier chains, implementation techniques for regenerative sampling circuits based on super-regenerative oscillators are presented. Finally, an analog-to-digital converter with outstanding performance and complete interfaces both to the analog baseband as well as to the digital side completes the set of building blocks for efficient ultra-high speed communication.

  20. Spinoff 1999

    NASA Technical Reports Server (NTRS)

    1999-01-01

    A survey is presented of NASA-developed technologies and systems that were reaching commercial application in the course of 1999. Attention is given to the contributions of each major NASA Research Center. Representative 'spinoff' technologies include the predictive AI engine monitoring system EMPAS, the GPS-based Wide Area Augmentation System for aircraft navigation, a CMOS-Active Pixel Sensor camera-on-a-chip, a marine spectroradiometer, portable fuel cells, hyperspectral camera technology, and a rapid-prototyping process for ceramic components.

  1. Controlled ecological life support system breadboard project, 1988

    NASA Technical Reports Server (NTRS)

    Knott, W. M.

    1990-01-01

    The Closed Ecological Life Support System (CELSS) Breadboard Project, NASA's effort to develop the technology required to produce a functioning bioregenerative system, is discussed. The different phases of the project and its current status are described. The relationship between the project components are shown, and major project activities for fiscal years 1989 to 1993 are listed. The Biomass Production Chamber (BPC) became operational and tests of wheat as a single crop are nearing completion.

  2. The National Disaster Medical System

    NASA Technical Reports Server (NTRS)

    Reutershan, Thomas P.

    1991-01-01

    The Emergency Mobilization Preparedness Board developed plans for improved national preparedness in case of major catastrophic domestic disaster or the possibility of an overseas conventional conflict. Within the health and medical arena, the working group on health developed the concept and system design for the National Disaster Medical System (NDMS). A description of NDMS is presented including the purpose, key components, medical response, patient evacuation, definitive medical care, NDMS activation and operations, and summary and benefits.

  3. Development of Advanced Environmental Barrier Coatings for SiC/SiC Composites at NASA GRC: Prime-Reliant Design and Durability Perspectives

    NASA Technical Reports Server (NTRS)

    Zhu, Dongming

    2017-01-01

    Environmental barrier coatings (EBCs) are considered technologically important because of the critical needs and their ability to effectively protect the turbine hot-section SiC/SiC ceramic matrix composite (CMC) components in harsh engine combustion environments. The development of NASA's advanced environmental barrier coatings have been aimed at significantly improved the coating system temperature capability, stability, erosion-impact, and CMAS resistance for SiC/SiC turbine airfoil and combustors component applications. The NASA environmental barrier coating developments have also emphasized thermo-mechanical creep and fatigue resistance in simulated engine heat flux and environments. Experimental results and models for advanced EBC systems will be presented to help establishing advanced EBC composition design methodologies, performance modeling and life predictions, for achieving prime-reliant, durable environmental coating systems for 2700-3000 F engine component applications. Major technical barriers in developing environmental barrier coating systems and the coating integration with next generation composites having further improved temperature capability, environmental stability, EBC-CMC fatigue-environment system durability will be discussed.

  4. The Development of Environmental Barrier Coatings for SiCSiC Ceramic Matrix Composites: Challenges and Opportunities

    NASA Technical Reports Server (NTRS)

    Zhu, Dongming

    2014-01-01

    Environmental barrier coatings (EBCs) and SiC/SiC ceramic matrix composites (CMCs) systems will play a crucial role in future turbine engines for hot-section component applications because of their ability to significantly increase engine operating temperatures, reduce engine weight and cooling requirements. The development of prime-reliant environmental barrier coatings is a key to enable the applications of the envisioned CMC components to help achieve next generation engine performance and durability goals. This paper will primarily address the performance requirements and design considerations of environmental barrier coatings for turbine engine applications. The emphasis is placed on current candidate environmental barrier coating systems for SiCSiC CMCs, their performance benefits and design limitations in long-term operation and combustion environments. Major technical barriers in developing advanced environmental barrier coating systems, the coating integrations with next generation CMC turbine components having improved environmental stability, cyclic durability and system performance will be described. The development trends for turbine environmental barrier coating systems by utilizing improved compositions, state-of-the-art processing methods, and simulated environment testing and durability modeling will be discussed.

  5. Activity Fund Accounting.

    ERIC Educational Resources Information Center

    Cool, David W.

    1983-01-01

    Addresses the need of school districts in many states to decide on an appropriate mingling of centralization and decentralization in the operation of activity funds. Argues for analysis of activity fund operation through a breakdown into such major components as policy, the accounting system, and reporting and auditing. (JBM)

  6. OPTIMIZATION OF DECENTRALIZED BMP CONTROLS IN URBAN AREAS

    EPA Science Inventory

    This paper will present an overview of a recently completed project for the US EPA entitled, Optimization of Urban Wet-weather Flow Control Systems. The focus of this effort is on techniques that are suitable for evaluating decentralized BMP controls. The four major components ...

  7. OPTIMIZATION OF DECENTRALIZED BMP CONTROLS IN URBAN AREAS

    EPA Science Inventory

    This paper will present an overview of a recently completed project for the US EPA entitled Optimization of Urban Wet-weather Flow Control Systems. The focus of this effort is on techniques that are suitable for evaluating decentralized BMP controls. The four major components o...

  8. Political Education as a Means of Political Socialization.

    ERIC Educational Resources Information Center

    Grabe, Weronika; Knobelsdorf, Wodzimierz

    1980-01-01

    This essay describes the dimensions of political socialization with systematic political education as a major component. Both promote individual acceptance of political norms--particularly where government and school systems are tightly linked. The authors argue that political socialization should promote effective citizenship rather than simply…

  9. Making Our Buildings Safer: Security Management and Equipment Issues.

    ERIC Educational Resources Information Center

    Clark, James H.

    1997-01-01

    Discusses three major components of library security: physical security of the environment; operating procedures for library staff, the public, and security personnel; and a contract security force (or campus security in academic institutions.) Topics include risk management; maintenance; appropriate technology, including security systems and…

  10. Computer-Aided Facilities Management Systems (CAFM).

    ERIC Educational Resources Information Center

    Cyros, Kreon L.

    Computer-aided facilities management (CAFM) refers to a collection of software used with increasing frequency by facilities managers. The six major CAFM components are discussed with respect to their usefulness and popularity in facilities management applications: (1) computer-aided design; (2) computer-aided engineering; (3) decision support…

  11. Programming Language CAMIL II: Implementation and Evaluation.

    ERIC Educational Resources Information Center

    Gardner, Edward

    A reimplementation of Computer assisted/managed instruction language (CAMIL) for qualitative and quantitative improvements in the software is presented. The reformatted language is described narratively, and major components of the system software are indicated and discussed. Authoring aids and imbedded support facilities are also described, and…

  12. GIS-based spatial decision support system for grain logistics management

    NASA Astrophysics Data System (ADS)

    Zhen, Tong; Ge, Hongyi; Jiang, Yuying; Che, Yi

    2010-07-01

    Grain logistics is the important component of the social logistics, which can be attributed to frequent circulation and the great quantity. At present time, there is no modern grain logistics distribution management system, and the logistics cost is the high. Geographic Information Systems (GIS) have been widely used for spatial data manipulation and model operations and provide effective decision support through its spatial database management capabilities and cartographic visualization. In the present paper, a spatial decision support system (SDSS) is proposed to support policy makers and to reduce the cost of grain logistics. The system is composed of two major components: grain logistics goods tracking model and vehicle routing problem optimization model and also allows incorporation of data coming from external sources. The proposed system is an effective tool to manage grain logistics in order to increase the speed of grain logistics and reduce the grain circulation cost.

  13. Energy Efficient Engine Flight Propulsion System Preliminary Analysis and Design Report

    NASA Technical Reports Server (NTRS)

    Bisset, J. W.; Howe, D. C.

    1983-01-01

    The final design and analysis of the flight propulsion system is presented. This system is the conceptual study engine defined to meet the performance, economic and environmental goals established for the Energy Efficient Engine Program. The design effort included a final definition of the engine, major components, internal subsystems, and nacelle. Various analytical representations and results from component technology programs are used to verify aerodynamic and structural design concepts and to predict performance. Specific design goals and specifications, reflecting future commercial aircraft propulsion system requirements for the mid-1980's, are detailed by NASA and used as guidelines during engine definition. Information is also included which details salient results from a separate study to define a turbofan propulsion system, known as the maximum efficiency engine, which reoptimized the advanced fuel saving technologies for improved fuel economy and direct operating costs relative to the flight propulsion system.

  14. Mimicking Insect Communication: Release and Detection of Pheromone, Biosynthesized by an Alcohol Acetyl Transferase Immobilized in a Microreactor

    PubMed Central

    Muñoz, Lourdes; Dimov, Nikolay; Carot-Sans, Gerard; Bula, Wojciech P.; Guerrero, Angel; Gardeniers, Han J. G. E.

    2012-01-01

    Infochemical production, release and detection of (Z,E)-9,11-tetradecadienyl acetate, the major component of the pheromone of the moth Spodoptera littoralis, is achieved in a novel microfluidic system designed to mimic the final step of the pheromone biosynthesis by immobilized recombinant alcohol acetyl transferase. The microfluidic system is part of an “artificial gland”, i.e., a chemoemitter that comprises a microreactor connected to a microevaporator and is able to produce and release a pre-defined amount of the major component of the pheromone from the corresponding (Z,E)-9,11-tetradecadienol. Performance of the entire chemoemitter has been assessed in electrophysiological and behavioral experiments. Electroantennographic depolarizations of the pheromone produced by the chemoemitter were ca. 40% relative to that evoked by the synthetic pheromone. In a wind tunnel, the pheromone released from the evaporator elicited on males a similar attraction behavior as 3 virgin females in most of the parameters considered. PMID:23155372

  15. Utilization of Pb-free solders in MEMS packaging

    NASA Astrophysics Data System (ADS)

    Selvaduray, Guna S.

    2003-01-01

    Soldering of components within a package plays an important role in providing electrical interconnection, mechanical integrity and thermal dissipation. MEMS packages present challenges that are more complex than microelectronic packages because they are far more sensitive to shock and vibration and also require precision alignment. Soldering is used at two major levels within a MEMS package: at the die attach level and at the component attach level. Emerging environmental regulations worldwide, notably in Europe and Japan, have targeted the elimination of Pb usage in electronic assemblies, due to the inherent toxicity of Pb. This has provided the driving force for development and deployment of Pb-free solder alloys. A relatively large number of Pb-free solder alloys have been proposed by various researchers and companies. Some of these alloys have also been patented. After several years of research, the solder alloy system that has emerged is based on Sn as a major component. The electronics industry has identified different compositions for different specific uses, such as wave soldering, surface mount reflow, etc. The factors that affect choice of an appropriate Pb-free solder can be divided into two major categories, those related to manufacturing, and those related to long term reliability and performance.

  16. Anti-Idling Battery for Truck Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Keith Kelly

    2011-09-30

    In accordance to the Assistance Agreement DE-EE0001036, the objective of this project was to develop an advanced high voltage lithium-ion battery for use in an all-electric HVAC system for Class-7-8 heavy duty trucks. This system will help heavy duty truck drivers meet the tough new anti-idling laws being implemented by over 23 states. Quallion will be partnering with a major OEM supplier of HVAC systems to develop this system. The major OEM supplier will provide Quallion the necessary interface requirements and HVAC hardware to ensure successful testing of the all-electric system. At the end of the program, Quallion will delivermore » test data on three (3) batteries as well as test data for the prototype HVAC system. The objectives of the program are: (1) Battery Development - Objective 1 - Define battery and electronics specifications in preparation for building the prototype module. (Completed - summary included in report) and Objective 2 - Establish a functional prototype battery and characterize three batteries in-house. (Completed - photos and data included in report); (2) HVAC Development - Objective 1 - Collaborate with manufacturers to define HVAC components, layout, and electronics in preparation for establishing the prototype system. (Completed - photos and data included in report) and Objective 2 - Acquire components for three functional prototypes for use by Quallion. (Completed - photos and data included in report).« less

  17. Integrating Emotion and Cognition in Successful Service Learning: A Complex System Approach (Invited)

    NASA Astrophysics Data System (ADS)

    Raia, F.

    2010-12-01

    Service-learning (S-L) has evolved as valuable pedagogic concept during the last two decades, based on the hypothesis that learning can best be accomplished when placed in the context of real-life social settings, e.g. schools, production, research, healthcare etc. What students learn in the academic course/context must be elaborated in the context of the S-L experience. In return for the authentic learning experience, the learner provides the service-provider with a "free" service. This reciprocality makes service-learning an appealing concept. Because of its attractive "win-win" design, the field of service-learning is continuously expanding. At a major public university CCNY with a very diverse student population, we were interested in developing and participating in S-L experience in the field of Earth System Science. We designed an upper level undergraduate course - Environmental Soil Science for Urban Sustainability - specifically targeted to students of Earth Science, Engineering, Economics and, Political Sciences to support environmental entrepreneurship. Specifically, we integrated S-L activities in the exploration of soil studies and urban agriculture. Students worked together in small groups both in class and for their S-L experience (30 hours) with urban garden and agriculture organizations. Students were required to apply the content learned in the academic course providing soil testing and soil evaluation to the partners, generate reports through a series of homework assignments and journal entries connecting three major components: Community Service, Personal Experience and Course Content. Our experience with this course shows the following results: S-L must be considered a complex system characterized by the continually changing interactions among the above mentioned three major components and three social and academic diverse groups of people involved: Students, Service-Providers and Academic Instructors. Because experience alone does not produce learning, this system requires participants to elaborate and connect the three major components and continually update, modify and build on the learning experience and personal growth. Critical reflection activities are considered to be a powerful tool to bridge community service activities and the educational content. Reflection activities gauge students’ expectations, thoughts and understanding and, by making these evident to the students, can reveal less obvious aspects of the experience and support different interpretations of an event. However, in the form of critical reflection, they tend to exclude the role emotion may play throughout the learning process specifically for one of the three components -Personal Growth. Moreover, in the last decade neuroscience and psychology research shows that emotion is indispensable for conceiving rational thoughts, understanding and memory development and that a purely cognitive view on learning is not working. In our course we strove to design reflections that involve emotion and cognition and their interdependence in connecting the three components of S-L. A complex system approach is fundamental when challenges of integrating emotion and cognition in Service Learning need to be addressed.

  18. Weighted Components of i-Government Enterprise Architecture

    NASA Astrophysics Data System (ADS)

    Budiardjo, E. K.; Firmansyah, G.; Hasibuan, Z. A.

    2017-01-01

    Lack of government performance, among others due to the lack of coordination and communication among government agencies. Whilst, Enterprise Architecture (EA) in the government can be use as a strategic planning tool to improve productivity, efficiency, and effectivity. However, the existence components of Government Enterprise Architecture (GEA) do not show level of importance, that cause difficulty in implementing good e-government for good governance. This study is to explore the weight of GEA components using Principal Component Analysis (PCA) in order to discovered an inherent structure of e-government. The results show that IT governance component of GEA play a major role in the GEA. The rest of components that consist of e-government system, e-government regulation, e-government management, and application key operational, contributed more or less the same. Beside that GEA from other countries analyzes using comparative base on comon enterprise architecture component. These weighted components use to construct i-Government enterprise architecture. and show the relative importance of component in order to established priorities in developing e-government.

  19. Strengthening Rehabilitation in Health Systems Worldwide by Integrating Information on Functioning in National Health Information Systems.

    PubMed

    Stucki, Gerold; Bickenbach, Jerome; Melvin, John

    2017-09-01

    A complete understanding of the experience of health requires information relevant not merely to the health indicators of mortality and morbidity but also to functioning-that is, information about what it means to live in a health state, "the lived experience of health." Not only is functioning information relevant to healthcare and the overall objectives of person-centered healthcare but to the successful operation of all components of health systems.In light of population aging and major epidemiological trends, the health strategy of rehabilitation, whose aim has always been to optimize functioning and minimize disability, will become a key health strategy. The increasing prominence of the rehabilitative strategy within the health system drives the argument for the integration of functioning information as an essential component in national health information systems.Rehabilitation professionals and researchers have long recognized in WHO's International Classification of Functioning, Disability and Health the best prospect for an internationally recognized, sufficiently complete and powerful information reference for the documentation of functioning information. This paper opens the discussion of the promise of integrating the ICF as an essential component in national health systems to secure access to functioning information for rehabilitation, across health systems and countries.

  20. Space Station logistic support by Aries

    NASA Astrophysics Data System (ADS)

    Cougnet, C.; Groepper, P.

    1987-10-01

    The architecture and functions of Aries, a low-cost expendable vehicle, are discussed. The Aries design is based on the Ariane 5 L5 and VEB. The major components of Aries are upgraded L5 and VEB and a payload adaptor; the design and operations of these components are described. The avionics and propulsion system for Aries are examined. Aries is to be employed for logistic support, assembly, and the placement of satellites. An example of a mission scenario and diagrams of Aries are provided.

  1. Vaccine allergy.

    PubMed

    Caubet, Jean-Christoph; Ponvert, Claude

    2014-08-01

    Overdiagnosis of vaccine allergy is considered a major public health problem. This article discusses the different types of allergic reactions after immunization based on the timing (immediate vs nonimmediate) and the extent of the reaction (local vs systemic). The vaccine components potentially responsible for an allergic reaction are discussed, as well as the management of patients with a history of reaction to a specific vaccine and those with a history of allergy to one of the vaccine components. Copyright © 2014 Elsevier Inc. All rights reserved.

  2. Islet organogenesis, angiogenesis and innervation.

    PubMed

    Cerf, Marlon E

    2011-11-01

    The pancreas is characterized by a major component, an exocrine and ductal system involved in digestion, and a minor component, the endocrine islets represented by islet micro-organs that tightly regulate glucose homoeostasis. Pancreatic organogenesis is strictly co-ordinated by transcription factors that are expressed sequentially to yield functional islets capable of maintaining glucose homoeostasis. Angiogenesis and innervation complete islet development, equipping islets to respond to metabolic demands. Proper regulation of this triad of processes during development is critical for establishing functional islets.

  3. Digital Systems Validation Handbook. Volume 2

    DTIC Science & Technology

    1989-02-01

    0 TABLE 7.2-3. FAILURE RATES FOR MAJOR RDFCS COMPONENTS COMPONENT UNIT FAILURE RATE* Pitch Angle Gyro 303 Roll Angle Gyro 303 Yaw Rate Gyro 200...Airplane Weight 314,500 lb Altitude 35 ft Angle of Attack 10.91 0 Indicated Air Speed 168 kts Flap Deployment 22 o Transition capability was added to go...various pieces of information into the form needed by the FCCs. For example, roll angle and pitch angle are converted to three-wire AC signals, properly

  4. Developing a 300C Analog Tool for EGS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Normann, Randy

    2015-03-23

    This paper covers the development of a 300°C geothermal well monitoring tool for supporting future EGS (enhanced geothermal systems) power production. This is the first of 3 tools planed. This is an analog tool designed for monitoring well pressure and temperature. There is discussion on 3 different circuit topologies and the development of the supporting surface electronics and software. There is information on testing electronic circuits and component. One of the major components is the cable used to connect the analog tool to the surface.

  5. Capacity on wireless quantum cellular communication system

    NASA Astrophysics Data System (ADS)

    Zhou, Xiang-Zhen; Yu, Xu-Tao; Zhang, Zai-Chen

    2018-03-01

    Quantum technology is making excellent prospects in future communication networks. Entanglement generation and purification are two major components in quantum networks. Combining these two techniques with classical cellular mobile communication, we proposed a novel wireless quantum cellular(WQC) communication system which is possible to realize commercial mobile quantum communication. In this paper, the architecture and network topology of WQC communication system are discussed, the mathematical model of WQC system is extracted and the serving capacity, indicating the ability to serve customers, is defined and calculated under certain circumstances.

  6. The planned Alaska SAR Facility - An overview

    NASA Technical Reports Server (NTRS)

    Carsey, Frank; Weeks, Wilford

    1987-01-01

    The Alaska SAR Facility (ASF) is described in an overview fashion. The facility consists of three major components, a Receiving Ground System, a SAR Processing System and an Analysis and Archiving System; the ASF Program also has a Science Working Team and the requisite management and operations systems. The ASF is now an approved and fully funded activity; detailed requirements and science background are presented for the facility to be implemented for data from the European ERS-1, the Japanese ERS-1 and Radarsat.

  7. V-SUIT Model Validation Using PLSS 1.0 Test Results

    NASA Technical Reports Server (NTRS)

    Olthoff, Claas

    2015-01-01

    The dynamic portable life support system (PLSS) simulation software Virtual Space Suit (V-SUIT) has been under development at the Technische Universitat Munchen since 2011 as a spin-off from the Virtual Habitat (V-HAB) project. The MATLAB(trademark)-based V-SUIT simulates space suit portable life support systems and their interaction with a detailed and also dynamic human model, as well as the dynamic external environment of a space suit moving on a planetary surface. To demonstrate the feasibility of a large, system level simulation like V-SUIT, a model of NASA's PLSS 1.0 prototype was created. This prototype was run through an extensive series of tests in 2011. Since the test setup was heavily instrumented, it produced a wealth of data making it ideal for model validation. The implemented model includes all components of the PLSS in both the ventilation and thermal loops. The major components are modeled in greater detail, while smaller and ancillary components are low fidelity black box models. The major components include the Rapid Cycle Amine (RCA) CO2 removal system, the Primary and Secondary Oxygen Assembly (POS/SOA), the Pressure Garment System Volume Simulator (PGSVS), the Human Metabolic Simulator (HMS), the heat exchanger between the ventilation and thermal loops, the Space Suit Water Membrane Evaporator (SWME) and finally the Liquid Cooling Garment Simulator (LCGS). Using the created model, dynamic simulations were performed using same test points also used during PLSS 1.0 testing. The results of the simulation were then compared to the test data with special focus on absolute values during the steady state phases and dynamic behavior during the transition between test points. Quantified simulation results are presented that demonstrate which areas of the V-SUIT model are in need of further refinement and those that are sufficiently close to the test results. Finally, lessons learned from the modelling and validation process are given in combination with implications for the future development of other PLSS models in V-SUIT.

  8. Domain specific software architectures: Command and control

    NASA Technical Reports Server (NTRS)

    Braun, Christine; Hatch, William; Ruegsegger, Theodore; Balzer, Bob; Feather, Martin; Goldman, Neil; Wile, Dave

    1992-01-01

    GTE is the Command and Control contractor for the Domain Specific Software Architectures program. The objective of this program is to develop and demonstrate an architecture-driven, component-based capability for the automated generation of command and control (C2) applications. Such a capability will significantly reduce the cost of C2 applications development and will lead to improved system quality and reliability through the use of proven architectures and components. A major focus of GTE's approach is the automated generation of application components in particular subdomains. Our initial work in this area has concentrated in the message handling subdomain; we have defined and prototyped an approach that can automate one of the most software-intensive parts of C2 systems development. This paper provides an overview of the GTE team's DSSA approach and then presents our work on automated support for message processing.

  9. Scale Effects on Magnet Systems of Heliotron-Type Reactors

    NASA Astrophysics Data System (ADS)

    S, Imagawa; A, Sagara

    2005-02-01

    For power plants heliotron-type reactors have attractive advantages, such as no current-disruptions, no current-drive, and wide space between helical coils for the maintenance of in-vessel components. However, one disadvantage is that a major radius has to be large enough to obtain large Q-value or to produce sufficient space for blankets. Although the larger radius is considered to increase the construction cost, the influence has not been understood clearly, yet. Scale effects on superconducting magnet systems have been estimated under the conditions of a constant energy confinement time and similar geometrical parameters. Since the necessary magnetic field with a larger radius becomes lower, the increase rate of the weight of the coil support to the major radius is less than the square root. The necessary major radius will be determined mainly by the blanket space. The appropriate major radius will be around 13 m for a reactor similar to the Large Helical Device (LHD).

  10. Development and Qualification of ATV Propulsion Assemblies

    NASA Astrophysics Data System (ADS)

    Riehle, M.; Jost, R.

    2002-01-01

    In the frame of the development and operation of the International Space Station ISS, the European Space Agency ESA is not only contributing experiments and a laboratory module but also logistics capacity. This purpose of supplying the ISS shall be covered by an unmanned, Automated Transfer Vehicle (ATV) that will be launched for the first time in 2004 by Ariane 5. The development of the ATV is in close conjunction to the future Ariane 5 launch capacity of about 20 tons injected into low earth orbit. Thus this unmanned transporter will be a quite large space craft that is subjected to fulfil several mission objectives apart of only delivering cargo such as multiple automatic docking/de-docking, re-boost services and re-fuelling. For those reasons and due to its dimensions the propulsion sub-system is one of the most sophisticated in the field of space propulsion. Even safety issues of manned space flight have to be applied since the pressurised cargo section is part of the ISS when docked to the manned modules. This leads to by far the largest but also the most sophisticated propulsion system ever built in Europe. Astrium as one of the major partners of this european project is responsible for this major system that will be described in the paper. Focusing on the major core assemblies such as multi thruster platforms, pressure control system incl. safety and redundancy mechanisms as well as tanks and other components that completes a propulsion system. System Design and Qualification Starting from the basic criteria the paper will present the major performance requirements such as pressures, thrust levels and other parameters that led to the selection of major components of the system such as thrusters, valves, tanks, etc. Some of the component could be selected from off the shelve, whereas other core components such as the 200N Attitude Control and Braking Thrusters or Propellant Tanks had to be newly developed. The stepwise approach of development and careful qualification will be presented starting from components and assemblies up to sub- system. Exemplarily, the path of the 200N shall be described in more detail since requirements of various kinds are to be applied here. This thruster is used in a total of 28 engines located on 4 thruster cluster assemblies on the bottom and 4 on the front of the space craft delivering steady state thrust as well as impulse bit to the ATV and can be used also as backup for the main thrusters. Safety and thus redundancy is one of the major driver for the design. As a first step i.e. the thrusters are equipped with measures to detect malfunctions and problems by continuous measuring chamber temperature and combustion pressure. The layout of the thruster clusters arrangement in combination with control electronics are such are such that multiple independent branches are controlling the system by which each of them could to fulfil the whole operational objectives. The thruster clusters are also affected by most of the environmental constraints that require careful thermal or mechanical design. For example severe shock loads induced by the stage separation nearby as well as meteorites and debris have to be taken into account for mechanical design. Or large transient pressure spikes and water hammer caused by simultaneous operation of thrusters have to be considered for hydraulic design. As well as extreme conditions for thermal design facing high thermal loads both radiation and conductive during thruster firing and sun exposure of the externally mounted assembly as well as low heater budget and I/F flux limitations when exposed to deep space during long phases. Intensive test programs have been carried out or are under preparation as well as complementary numerical analysis are completing and supporting each step of the development. The paper will describe those design and qualification activities as well as the results as far as available to that time in order to give an overview of the status of the development of the whole propulsion system.

  11. Direct conversion of algal biomass to biofuel

    DOEpatents

    Deng, Shuguang; Patil, Prafulla D; Gude, Veera Gnaneswar

    2014-10-14

    A method and system for providing direct conversion of algal biomass. Optionally, the method and system can be used to directly convert dry algal biomass to biodiesels under microwave irradiation by combining the reaction and combining steps. Alternatively, wet algae can be directly processed and converted to fatty acid methyl esters, which have the major components of biodiesels, by reacting with methanol at predetermined pressure and temperature ranges.

  12. Global Gene Expression Profiles Identify Metastasis Regulatory Networks | Center for Cancer Research

    Cancer.gov

    Metastasis is a systemic disease in which cancer cells break away from a tumor and migrate to other parts of the body, usually via the blood or lymphatic systems, to form new tumors. Metastatic tumors are difficult to treat and account for the majority of cancer-related deaths. Susceptibility to metastasis is known to have a genetic component, with some individuals more

  13. Soluble components of the flagellar export apparatus, FliI, FliJ, and FliH, do not deliver flagellin, the major filament protein, from the cytosol to the export gate.

    PubMed

    Sajó, Ráchel; Liliom, Károly; Muskotál, Adél; Klein, Agnes; Závodszky, Péter; Vonderviszt, Ferenc; Dobó, József

    2014-11-01

    Flagella, the locomotion organelles of bacteria, extend from the cytoplasm to the cell exterior. External flagellar proteins are synthesized in the cytoplasm and exported by the flagellar type III secretion system. Soluble components of the flagellar export apparatus, FliI, FliH, and FliJ, have been implicated to carry late export substrates in complex with their cognate chaperones from the cytoplasm to the export gate. The importance of the soluble components in the delivery of the three minor late substrates FlgK, FlgL (hook-filament junction) and FliD (filament-cap) has been convincingly demonstrated, but their role in the transport of the major filament component flagellin (FliC) is still unclear. We have used continuous ATPase activity measurements and quartz crystal microbalance (QCM) studies to characterize interactions between the soluble export components and flagellin or the FliC:FliS substrate-chaperone complex. As controls, interactions between soluble export component pairs were characterized providing Kd values. FliC or FliC:FliS did not influence the ATPase activity of FliI alone or in complex with FliH and/or FliJ suggesting lack of interaction in solution. Immobilized FliI, FliH, or FliJ did not interact with FliC or FliC:FliS detected by QCM. The lack of interaction in the fluid phase between FliC or FliC:FliS and the soluble export components, in particular with the ATPase FliI, suggests that cells use different mechanisms for the export of late minor substrates, and the major substrate, FliC. It seems that the abundantly produced flagellin does not require the assistance of the soluble export components to efficiently reach the export gate. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. Norm-Referenced Tests. Summary. REL 2014-004

    ERIC Educational Resources Information Center

    Stuit, David; Austin, Megan J.; Berends, Mark; Gerdeman, R. Dean

    2014-01-01

    Recent changes to state laws on accountability have prompted school districts to design teacher performance evaluation systems that incorporate student achievement (student growth) as a major component. As a consequence, some states and districts are considering teacher value- added models as part of teacher performance evaluations. Value-added…

  15. Norm-Referenced Tests. REL 2014-004

    ERIC Educational Resources Information Center

    Stuit, David; Austin, Megan J.; Berends, Mark; Gerdeman, R. Dean

    2014-01-01

    Recent changes to state laws on accountability have prompted school districts to design teacher performance evaluation systems that incorporate student achievement (student growth) as a major component. As a consequence, some states and districts are considering teacher value-added models as part of teacher performance evaluations. Value-added…

  16. Stressed lungs: unveiling the role of circulating stress hormones in ozone-induced lung injury and inflammation.

    EPA Science Inventory

    Ozone, a major component of smog generated through the interaction of light and anthropogenic emissions, induces adverse pulmonary, cardiovascular, and systemic health effects upon inhalation. It is generally accepted that ozone-induced lung injury is mediated by its interaction ...

  17. Earth Without Life: A Systems Model of a Global Abiotic Nitrogen Cycle

    NASA Astrophysics Data System (ADS)

    Laneuville, M.; Kameya, M.; Cleaves, H. J.

    2017-07-01

    N is the major component of the atmosphere and plays important roles in biochemistry. Presently, the surface N-cycle is dominated by biology. However, before the origin of life, abiotic N-cycling would have set the stage for the origin of life.

  18. Urban/rural connections: the New York City watershed

    USDA-ARS?s Scientific Manuscript database

    The Cannonsville Reservoir, which was placed in service in 1964, is a major component of the unfiltered New York City water supply system. This year, the Watershed Agricultural Program marks a 17-year history of collaboration among producers, the Natural Resources Conservation Service (NRCS), the De...

  19. A Small Business Management Entrepreneurship Curriculum: A Dual Progression Experience.

    ERIC Educational Resources Information Center

    Kuratko, Donald; LaFollette, William R.

    1986-01-01

    Describes Ball State University's "dual progression" curriculum for the small business management program. The program seeks to combine the best elements of entrepreneurial theory with the difficult facets of practical experience. The five major component courses (small business ventures, entrepreneurship, management information systems,…

  20. Research Needs for Rural Public Services.

    ERIC Educational Resources Information Center

    Stocker, Frederick D.

    The report proposes a conceptual framework for researching key issues relating to rural public facility policy affecting such services as fire protection, water systems, roads, wastewater treatment, hospitals, and others, and identifies important research needs in this area. Major components of the framework are sources of financing (private and…

  1. INTRODUCTION OF BIOMASS AS RENEWABLE ENERGY COMPONENT OF FUTURE TRANSPORTATION FUELS

    EPA Science Inventory

    The long-term objectives of new vehicle/fuel systems require the reduction of petroleum use, reduction of air pollution emissions, and reduction of greenhouse gas (GHG) emissions. In the near term, a major advancement toward these objectives will be made possible by the improved ...

  2. Computer Models Identify Methods to Reduce Bridge Cracks During Production Processes : Brief

    DOT National Transportation Integrated Search

    2012-06-01

    While most motorists see only the bridge deck, strong bridge girders are the basis for a stable system to support the traffic-handling surface. Concrete bridge girders often have two major components: the web, which is an I-shaped cross section and v...

  3. Allergen extracts and recombinant proteins: comparison of efficiency of in vitro allergy diagnostics using multiplex assay on a biological microchip.

    PubMed

    Smoldovskaya, Olga; Feyzkhanova, Guzel; Arefieva, Alla; Voloshin, Sergei; Ivashkina, Olga; Reznikov, Yuriy; Rubina, Alla

    2016-01-01

    Immunological test systems for diagnostics of type I hypersensitivity involve the following types of antigens: whole allergen extracts, individual highly purified proteins and their recombinant analogues. The goal of this study was to compare the results obtained with whole allergen extracts (birch pollen, cat dander, and timothy grass pollen) and their respective recombinant proteins in biochip-based immunoassay. Multiplex fluorescent immunoassay of 139 patients' blood serum samples was carried out using biological microchips (biochips). sIgE concentrations for the chosen allergens and their recombinant components were measured. ROC analysis was used for comparison of the results and determination of diagnostic accuracy. The results for the birch pollen extract and its recombinant allergens have shown that the diagnostic accuracy of the methods utilizing the whole allergen extract, its major component Bet v 1 and the combination of major and minor components (Bet v 1 and Bet v 2) was the same. Values for diagnostic accuracy for the cat dander extract and its major recombinant component Fel d 1 were equal. In contrast with birch pollen and cat dander allergens, using of recombinant components of timothy grass pollen (Phl p 1, Phl p 5, Phl p 7 and Phl p 12) did not allow reaching the diagnostic accuracy of using natural extract. Multiplex analysis of samples obtained from patients with allergy to birch pollen and cat dander using biological microchips has shown that comparable accuracy was observed for the assay with natural extracts and recombinant allergens. In the case of timothy grass allergen, using the recombinant components may be insufficient.

  4. DVV: a taxonomy for mixed reality visualization in image guided surgery.

    PubMed

    Kersten-Oertel, Marta; Jannin, Pierre; Collins, D Louis

    2012-02-01

    Mixed reality visualizations are increasingly studied for use in image guided surgery (IGS) systems, yet few mixed reality systems have been introduced for daily use into the operating room (OR). This may be the result of several factors: the systems are developed from a technical perspective, are rarely evaluated in the field, and/or lack consideration of the end user and the constraints of the OR. We introduce the Data, Visualization processing, View (DVV) taxonomy which defines each of the major components required to implement a mixed reality IGS system. We propose that these components be considered and used as validation criteria for introducing a mixed reality IGS system into the OR. A taxonomy of IGS visualization systems is a step toward developing a common language that will help developers and end users discuss and understand the constituents of a mixed reality visualization system, facilitating a greater presence of future systems in the OR. We evaluate the DVV taxonomy based on its goodness of fit and completeness. We demonstrate the utility of the DVV taxonomy by classifying 17 state-of-the-art research papers in the domain of mixed reality visualization IGS systems. Our classification shows that few IGS visualization systems' components have been validated and even fewer are evaluated.

  5. Characterising the development of the understanding of human body systems in high-school biology students - a longitudinal study

    NASA Astrophysics Data System (ADS)

    Snapir, Zohar; Eberbach, Catherine; Ben-Zvi-Assaraf, Orit; Hmelo-Silver, Cindy; Tripto, Jaklin

    2017-10-01

    Science education today has become increasingly focused on research into complex natural, social and technological systems. In this study, we examined the development of high-school biology students' systems understanding of the human body, in a three-year longitudinal study. The development of the students' system understanding was evaluated using the Components Mechanisms Phenomena (CMP) framework for conceptual representation. We coded and analysed the repertory grid personal constructs of 67 high-school biology students at 4 points throughout the study. Our data analysis builds on the assumption that systems understanding entails a perception of all the system categories, including structures within the system (its Components), specific processes and interactions at the macro and micro levels (Mechanisms), and the Phenomena that present the macro scale of processes and patterns within a system. Our findings suggest that as the learning process progressed, the systems understanding of our students became more advanced, moving forward within each of the major CMP categories. Moreover, there was an increase in the mechanism complexity presented by the students, manifested by more students describing mechanisms at the molecular level. Thus, the 'mechanism' category and the micro level are critical components that enable students to understand system-level phenomena such as homeostasis.

  6. Numerical simulation of vehicle crashworthiness and occupant protection

    NASA Astrophysics Data System (ADS)

    Saha, Nripen K.

    1993-08-01

    Numerical simulation of vehicle crashworthiness and occupant protection are addressed. The vehicle crashworthiness design objectives are to design the vehicle structure for optimum impact energy absorption, and to design the restraint system (seatbelts, airbags, bolsters, etc.) for optimum occupant protection. The following approaches are taken; a major part of the impact energy is to be absorbed by the vehicle structure; the restraint components will provide protection against the remaining crash energy; certain vehicle components are designed to deform under specific types and speeds of impact in a desired mode for sound energy management; structural components such as front side rails, rear rails, door structure and pillars undergo large amounts of deformation; and with properly designed geometry and material these components assist in mitigating the effects of impact.

  7. Numerical simulation of vehicle crashworthiness and occupant protection

    NASA Technical Reports Server (NTRS)

    Saha, Nripen K.

    1993-01-01

    Numerical simulation of vehicle crashworthiness and occupant protection are addressed. The vehicle crashworthiness design objectives are to design the vehicle structure for optimum impact energy absorption, and to design the restraint system (seatbelts, airbags, bolsters, etc.) for optimum occupant protection. The following approaches are taken; a major part of the impact energy is to be absorbed by the vehicle structure; the restraint components will provide protection against the remaining crash energy; certain vehicle components are designed to deform under specific types and speeds of impact in a desired mode for sound energy management; structural components such as front side rails, rear rails, door structure and pillars undergo large amounts of deformation; and with properly designed geometry and material these components assist in mitigating the effects of impact.

  8. The NASA-Lewis/ERDA solar heating and cooling technology program. [project planning/energy policy

    NASA Technical Reports Server (NTRS)

    Couch, J. P.; Bloomfield, H. S.

    1975-01-01

    Plans by NASA to carry out a major role in a solar heating and cooling program are presented. This role would be to create and test the enabling technology for future solar heating, cooling, and combined heating/cooling systems. The major objectives of the project are to achieve reduction in solar energy system costs, while maintaining adequate performance, reliability, life, and maintenance characteristics. The project approach is discussed, and will be accomplished principally by contract with industry to develop advanced components and subsystems. Advanced hardware will be tested to establish 'technology readiness' both under controlled laboratory conditions and under real sun conditions.

  9. Results of NASA/Army transmission research

    NASA Technical Reports Server (NTRS)

    Coy, John J.; Townsend, Dennis P.; Coe, Harold H.

    1988-01-01

    Since 1970 the NASA Lewis Research Center and the U.S. Army Aviation Systems Command have shared an interest in advancing the technology for helicopter propulsion systems. In particular, that portion of the program that applies to the drive train and its various mechanical components are outlined. The major goals of the program were (and continue to be) to increase the life, reliability, and maintainability, reduce the weight, noise, and vibration, and maintain the relatively high mechanical efficiency of the gear train. Major historical milestones are reviewed, significant advances in technology for bearings, gears, and transmissions are discussed, and the outlook for the future is presented. The reference list is comprehensive.

  10. Hybrid optical (freeform) components--functionalization of nonplanar optical surfaces by direct picosecond laser ablation.

    PubMed

    Kleindienst, Roman; Kampmann, Ronald; Stoebenau, Sebastian; Sinzinger, Stefan

    2011-07-01

    The performance of optical systems is typically improved by increasing the number of conventionally fabricated optical components (spheres, aspheres, and gratings). This approach is automatically connected to a system enlargement, as well as potentially higher assembly and maintenance costs. Hybrid optical freeform components can help to overcome this trade-off. They merge several optical functions within fewer but more complex optical surfaces, e.g., elements comprising shallow refractive/reflective and high-frequency diffractive structures. However, providing the flexibility and precision essential for their realization is one of the major challenges in the field of optical component fabrication. In this article we present tailored integrated machining techniques suitable for rapid prototyping as well as the fabrication of molding tools for low-cost mass replication of hybrid optical freeform components. To produce the different feature sizes with optical surface quality, we successively combine mechanical machining modes (ultraprecision micromilling and fly cutting) with precisely aligned direct picosecond laser ablation in an integrated fabrication approach. The fabrication accuracy and surface quality achieved by our integrated fabrication approach are demonstrated with profilometric measurements and experimental investigations of the optical performance.

  11. The Multiple Gyrotron System on the DIII-D Tokamak

    DOE PAGES

    Lohr, J.; Anderson, J.; Brambila, R.; ...

    2015-08-28

    A major component of the versatile heating systems on the DIII-D tokamak is the gyrotron complex. This system routinely operates at 110 GHz with 4.7 MW generated rf power for electron cyclotron heating and current drive. The complex is being upgraded with the addition of new depressed collector potential gyrotrons operating at 117.5 GHz and generating rf power in excess of 1.0 MW each. The long term upgrade plan calls for 10 gyrotrons at the higher frequency being phased in as resources permit, for an injected power near 10 MW. This article presents a summary of the current status ofmore » the DIII-D gyrotron complex, its performance, individual components, testing procedures, operational parameters, plans, and a brief summary of the experiments for which the system is currently being used.« less

  12. Time-Varying, Multi-Scale Adaptive System Reliability Analysis of Lifeline Infrastructure Networks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gearhart, Jared Lee; Kurtz, Nolan Scot

    2014-09-01

    The majority of current societal and economic needs world-wide are met by the existing networked, civil infrastructure. Because the cost of managing such infrastructure is high and increases with time, risk-informed decision making is essential for those with management responsibilities for these systems. To address such concerns, a methodology that accounts for new information, deterioration, component models, component importance, group importance, network reliability, hierarchical structure organization, and efficiency concerns has been developed. This methodology analyzes the use of new information through the lens of adaptive Importance Sampling for structural reliability problems. Deterioration, multi-scale bridge models, and time-variant component importance aremore » investigated for a specific network. Furthermore, both bridge and pipeline networks are studied for group and component importance, as well as for hierarchical structures in the context of specific networks. Efficiency is the primary driver throughout this study. With this risk-informed approach, those responsible for management can address deteriorating infrastructure networks in an organized manner.« less

  13. Theoretical models for coronary vascular biomechanics: Progress & challenges

    PubMed Central

    Waters, Sarah L.; Alastruey, Jordi; Beard, Daniel A.; Bovendeerd, Peter H.M.; Davies, Peter F.; Jayaraman, Girija; Jensen, Oliver E.; Lee, Jack; Parker, Kim H.; Popel, Aleksander S.; Secomb, Timothy W.; Siebes, Maria; Sherwin, Spencer J.; Shipley, Rebecca J.; Smith, Nicolas P.; van de Vosse, Frans N.

    2013-01-01

    A key aim of the cardiac Physiome Project is to develop theoretical models to simulate the functional behaviour of the heart under physiological and pathophysiological conditions. Heart function is critically dependent on the delivery of an adequate blood supply to the myocardium via the coronary vasculature. Key to this critical function of the coronary vasculature is system dynamics that emerge via the interactions of the numerous constituent components at a range of spatial and temporal scales. Here, we focus on several components for which theoretical approaches can be applied, including vascular structure and mechanics, blood flow and mass transport, flow regulation, angiogenesis and vascular remodelling, and vascular cellular mechanics. For each component, we summarise the current state of the art in model development, and discuss areas requiring further research. We highlight the major challenges associated with integrating the component models to develop a computational tool that can ultimately be used to simulate the responses of the coronary vascular system to changing demands and to diseases and therapies. PMID:21040741

  14. Source-to-Sink System Evolution as Recorded in Clastic Facies in Two New Zealand Examples: the Bounty System of South Island and the Waipaoa System of North Island

    NASA Astrophysics Data System (ADS)

    Marsaglia, K. M.

    2010-12-01

    New Zealand river sources and their submarine sinks are excellent examples for modeling source-to-sink systems. In particular, the sand fractions of these systems can be used as tracers to document links and/or disconnects between fluvial, shelf, slope, and bathyal components. Within any given system, the ability to use sand as a tracer depends on the nature of the rocks exposed in source river drainage basins. In evolving systems, the potential for erosional unroofing, change of outcrop lithology through time, can be important. Additionally, the ability of a given lithology to generate sediment of a certain size may also vary. For example in the New Zealand examples, Cenozoic mudstones generate mostly mud but can liberate recycled sand grains (if present), as well as a smaller proportion of mudstone lithic fragments depending on degree of mudstone induration; schist generates copious sand and quartz-vein pebbles; and thin-bedded sandy turbidites can generate significant gravel, as well as mud and sand. Sediment production mode also comes into play with glacial processes (South Island) generating rock flour, as well as coarser debris. The major outcropping unit across both islands is a sedimentary to metasedimentary forearc succession, the Torlesse Terrane. It served as the protolith of the Otago schist (South Island) and the source of detritus for Cretaceous and Cenozoic sedimentary units on both islands. Local magmatism also supplied sand-sized material: intraplate (South Island) volcanism produced intrabasinal epiclastic debris and magmatic arc (North Island) volcanism produced extrabasinal pyroclastic debris. Various lithologies have characteristic detrital signatures. For example, in the Cenozoic units of the Waipaoa system, Pliocene calcareous mudstone fragments are key lithic components in tracing sediment transport from source-to sink, whereas the major fingerprint of Otago schist input into the Bounty System of South Island is mica. Critical to defining sedimentary budgets in both New Zealand systems is defining the net proportion of dip-fed vs. strike-fed clastic components. The former are supplied directly to the system by coast-perpendicular rivers, and the latter are transported into or out of the system by coast-parallel currents (e.g., longshore, shelf, slope). Tectonic events in the fluvial drainage basin can also have major influences on the supply of sediment to offshore basins. There is evidence for lacustrine sediment traps in each New Zealand system and evidence, in at least one case, that they modified sediment input to the marine part of the system (Bounty Fan).

  15. Performance Metrics for Liquid Chromatography-Tandem Mass Spectrometry Systems in Proteomics Analyses*

    PubMed Central

    Rudnick, Paul A.; Clauser, Karl R.; Kilpatrick, Lisa E.; Tchekhovskoi, Dmitrii V.; Neta, Pedatsur; Blonder, Nikša; Billheimer, Dean D.; Blackman, Ronald K.; Bunk, David M.; Cardasis, Helene L.; Ham, Amy-Joan L.; Jaffe, Jacob D.; Kinsinger, Christopher R.; Mesri, Mehdi; Neubert, Thomas A.; Schilling, Birgit; Tabb, David L.; Tegeler, Tony J.; Vega-Montoto, Lorenzo; Variyath, Asokan Mulayath; Wang, Mu; Wang, Pei; Whiteaker, Jeffrey R.; Zimmerman, Lisa J.; Carr, Steven A.; Fisher, Susan J.; Gibson, Bradford W.; Paulovich, Amanda G.; Regnier, Fred E.; Rodriguez, Henry; Spiegelman, Cliff; Tempst, Paul; Liebler, Daniel C.; Stein, Stephen E.

    2010-01-01

    A major unmet need in LC-MS/MS-based proteomics analyses is a set of tools for quantitative assessment of system performance and evaluation of technical variability. Here we describe 46 system performance metrics for monitoring chromatographic performance, electrospray source stability, MS1 and MS2 signals, dynamic sampling of ions for MS/MS, and peptide identification. Applied to data sets from replicate LC-MS/MS analyses, these metrics displayed consistent, reasonable responses to controlled perturbations. The metrics typically displayed variations less than 10% and thus can reveal even subtle differences in performance of system components. Analyses of data from interlaboratory studies conducted under a common standard operating procedure identified outlier data and provided clues to specific causes. Moreover, interlaboratory variation reflected by the metrics indicates which system components vary the most between laboratories. Application of these metrics enables rational, quantitative quality assessment for proteomics and other LC-MS/MS analytical applications. PMID:19837981

  16. ETF system code: composition and applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reid, R.L.; Wu, K.F.

    1980-01-01

    A computer code has been developed for application to ETF tokamak system and conceptual design studies. The code determines cost, performance, configuration, and technology requirements as a function of tokamak parameters. The ETF code is structured in a modular fashion in order to allow independent modeling of each major tokamak component. The primary benefit of modularization is that it allows updating of a component module, such as the TF coil module, without disturbing the remainder of the system code as long as the input/output to the modules remains unchanged. The modules may be run independently to perform specific design studies,more » such as determining the effect of allowable strain on TF coil structural requirements, or the modules may be executed together as a system to determine global effects, such as defining the impact of aspect ratio on the entire tokamak system.« less

  17. The development of a program analysis environment for Ada

    NASA Technical Reports Server (NTRS)

    Brown, David B.; Carlisle, Homer W.; Chang, Kai-Hsiung; Cross, James H.; Deason, William H.; Haga, Kevin D.; Huggins, John R.; Keleher, William R. A.; Starke, Benjamin B.; Weyrich, Orville R.

    1989-01-01

    A unit level, Ada software module testing system, called Query Utility Environment for Software Testing of Ada (QUEST/Ada), is described. The project calls for the design and development of a prototype system. QUEST/Ada design began with a definition of the overall system structure and a description of component dependencies. The project team was divided into three groups to resolve the preliminary designs of the parser/scanner: the test data generator, and the test coverage analyzer. The Phase 1 report is a working document from which the system documentation will evolve. It provides history, a guide to report sections, a literature review, the definition of the system structure and high level interfaces, descriptions of the prototype scope, the three major components, and the plan for the remainder of the project. The appendices include specifications, statistics, two papers derived from the current research, a preliminary users' manual, and the proposal and work plan for Phase 2.

  18. Earthquake Hazards and Lifelines in the Interstate 5 Urban Corridor - Woodburn, Oregon, to Centralia, Washington

    USGS Publications Warehouse

    Barnett, E.A.; Weaver, C.S.; Meagher, K.L.; Haugerud, R.A.; Wang, Z.; Madin, I.P.; Wang, Y.; Wells, R.E.; Blakely, R.J.; Ballantyne, D.B.; Darienzo, M.

    2009-01-01

    The Interstate 5 highway (I-5) corridor, which stretches from Mexico to Canada, is both the main economic artery of the Pacific Northwest and home to the majority of Oregonians and Washingtonians. Accordingly, most regional utility and transportation systems have major components located within the I-5 corridor. For the purposes of this map, we refer to these essential systems as lifeline systems. The Pacific Northwest section of I-5, the I-5 urban corridor, extends from Eugene, Oregon, to the border of Canada. The population of this region is rapidly increasing with the bulk of growth and economic development centered in the cities of Eugene, Salem, and Portland, Oregon, and Olympia, Tacoma, Seattle, Everett, and Bellingham, Washington.

  19. Earthquake Hazards and Lifelines in the Interstate 5 Urban Corridor - Cottage Grove to Woodburn, Oregon

    USGS Publications Warehouse

    Barnett, E.A.; Weaver, C.S.; Meagher, K.L.; Haugerud, R.A.; Wang, Z.; Madin, I.P.; Wang, Y.; Wells, R.E.; Blakely, R.J.; Ballantyne, D.B.; Darienzo, M.

    2009-01-01

    The Interstate 5 highway (I-5) corridor, which stretches from Mexico to Canada, is both the main economic artery of the Pacific Northwest and home to the majority of Oregonians and Washingtonians. Accordingly, most regional utility and transportation systems have major components located within the I-5 corridor. For the purposes of this map, we refer to these essential systems as lifeline systems. The Pacific Northwest section of I-5, the I-5 urban corridor, extends from Eugene, Oregon, to the border of Canada. The population of this region is rapidly increasing with the bulk of growth and economic development centered in the cities of Eugene, Salem, and Portland, Oregon, and Olympia, Tacoma, Seattle, Everett, and Bellingham, Washington.

  20. Biomedical engineering strategies in system design space.

    PubMed

    Savageau, Michael A

    2011-04-01

    Modern systems biology and synthetic bioengineering face two major challenges in relating properties of the genetic components of a natural or engineered system to its integrated behavior. The first is the fundamental unsolved problem of relating the digital representation of the genotype to the analog representation of the parameters for the molecular components. For example, knowing the DNA sequence does not allow one to determine the kinetic parameters of an enzyme. The second is the fundamental unsolved problem of relating the parameters of the components and the environment to the phenotype of the global system. For example, knowing the parameters does not tell one how many qualitatively distinct phenotypes are in the organism's repertoire or the relative fitness of the phenotypes in different environments. These also are challenges for biomedical engineers as they attempt to develop therapeutic strategies to treat pathology or to redirect normal cellular functions for biotechnological purposes. In this article, the second of these fundamental challenges will be addressed, and the notion of a "system design space" for relating the parameter space of components to the phenotype space of bioengineering systems will be focused upon. First, the concept of a system design space will be motivated by introducing one of its key components from an intuitive perspective. Second, a simple linear example will be used to illustrate a generic method for constructing the design space in which qualitatively distinct phenotypes can be identified and counted, their fitness analyzed and compared, and their tolerance to change measured. Third, two examples of nonlinear systems from different areas of biomedical engineering will be presented. Finally, after giving reference to a few other applications that have made use of the system design space approach to reveal important design principles, some concluding remarks concerning challenges and opportunities for further development will be made.

  1. Chemical annotation of small and peptide-like molecules at the Protein Data Bank

    PubMed Central

    Young, Jasmine Y.; Feng, Zukang; Dimitropoulos, Dimitris; Sala, Raul; Westbrook, John; Zhuravleva, Marina; Shao, Chenghua; Quesada, Martha; Peisach, Ezra; Berman, Helen M.

    2013-01-01

    Over the past decade, the number of polymers and their complexes with small molecules in the Protein Data Bank archive (PDB) has continued to increase significantly. To support scientific advancements and ensure the best quality and completeness of the data files over the next 10 years and beyond, the Worldwide PDB partnership that manages the PDB archive is developing a new deposition and annotation system. This system focuses on efficient data capture across all supported experimental methods. The new deposition and annotation system is composed of four major modules that together support all of the processing requirements for a PDB entry. In this article, we describe one such module called the Chemical Component Annotation Tool. This tool uses information from both the Chemical Component Dictionary and Biologically Interesting molecule Reference Dictionary to aid in annotation. Benchmark studies have shown that the Chemical Component Annotation Tool provides significant improvements in processing efficiency and data quality. Database URL: http://wwpdb.org PMID:24291661

  2. Chemical annotation of small and peptide-like molecules at the Protein Data Bank.

    PubMed

    Young, Jasmine Y; Feng, Zukang; Dimitropoulos, Dimitris; Sala, Raul; Westbrook, John; Zhuravleva, Marina; Shao, Chenghua; Quesada, Martha; Peisach, Ezra; Berman, Helen M

    2013-01-01

    Over the past decade, the number of polymers and their complexes with small molecules in the Protein Data Bank archive (PDB) has continued to increase significantly. To support scientific advancements and ensure the best quality and completeness of the data files over the next 10 years and beyond, the Worldwide PDB partnership that manages the PDB archive is developing a new deposition and annotation system. This system focuses on efficient data capture across all supported experimental methods. The new deposition and annotation system is composed of four major modules that together support all of the processing requirements for a PDB entry. In this article, we describe one such module called the Chemical Component Annotation Tool. This tool uses information from both the Chemical Component Dictionary and Biologically Interesting molecule Reference Dictionary to aid in annotation. Benchmark studies have shown that the Chemical Component Annotation Tool provides significant improvements in processing efficiency and data quality. Database URL: http://wwpdb.org.

  3. Dynamic energy budget modeling reveals the potential of future growth and calcification for the coccolithophore Emiliania huxleyi in an acidified ocean.

    PubMed

    Muller, Erik B; Nisbet, Roger M

    2014-06-01

    Ocean acidification is likely to impact the calcification potential of marine organisms. In part due to the covarying nature of the ocean carbonate system components, including pH and CO2 and CO3(2-) levels, it remains largely unclear how each of these components may affect calcification rates quantitatively. We develop a process-based bioenergetic model that explains how several components of the ocean carbonate system collectively affect growth and calcification rates in Emiliania huxleyi, which plays a major role in marine primary production and biogeochemical carbon cycling. The model predicts that under the IPCC A2 emission scenario, its growth and calcification potential will have decreased by the end of the century, although those reductions are relatively modest. We anticipate that our model will be relevant for many other marine calcifying organisms, and that it can be used to improve our understanding of the impact of climate change on marine systems. © 2014 John Wiley & Sons Ltd.

  4. A Practical Approach to Starting Fission Surface Power Development

    NASA Technical Reports Server (NTRS)

    Mason, Lee S.

    2006-01-01

    The Prometheus Power and Propulsion Program has been reformulated to address NASA needs relative to lunar and Mars exploration. Emphasis has switched from the Jupiter Icy Moons Orbiter (JIMO) flight system development to more generalized technology development addressing Fission Surface Power (FSP) and Nuclear Thermal Propulsion (NTP). Current NASA budget priorities and the deferred mission need date for nuclear systems prohibit a fully funded reactor Flight Development Program. However, a modestly funded Advanced Technology Program can and should be conducted to reduce the risk and cost of future flight systems. A potential roadmap for FSP technology development leading to possible flight applications could include three elements: 1) Conceptual Design Studies, 2) Advanced Component Technology, and 3) Non-Nuclear System Testing. The Conceptual Design Studies would expand on recent NASA and DOE analyses while increasing the depth of study in areas of greatest uncertainty such as reactor integration and human-rated shielding. The Advanced Component Technology element would address the major technology risks through development and testing of reactor fuels, structural materials, primary loop components, shielding, power conversion, heat rejection, and power management and distribution (PMAD). The Non-Nuclear System Testing would provide a modular, technology testbed to investigate and resolve system integration issues.

  5. Dynamic analysis of Space Shuttle/RMS configuration using continuum approach

    NASA Technical Reports Server (NTRS)

    Ramakrishnan, Jayant; Taylor, Lawrence W., Jr.

    1994-01-01

    The initial assembly of Space Station Freedom involves the Space Shuttle, its Remote Manipulation System (RMS) and the evolving Space Station Freedom. The dynamics of this coupled system involves both the structural and the control system dynamics of each of these components. The modeling and analysis of such an assembly is made even more formidable by kinematic and joint nonlinearities. The current practice of modeling such flexible structures is to use finite element modeling in which the mass and interior dynamics is ignored between thousands of nodes, for each major component. The model characteristics of only tens of modes are kept out of thousands which are calculated. The components are then connected by approximating the boundary conditions and inserting the control system dynamics. In this paper continuum models are used instead of finite element models because of the improved accuracy, reduced number of model parameters, the avoidance of model order reduction, and the ability to represent the structural and control system dynamics in the same system of equations. Dynamic analysis of linear versions of the model is performed and compared with finite element model results. Additionally, the transfer matrix to continuum modeling is presented.

  6. Global search tool for the Advanced Photon Source Integrated Relational Model of Installed Systems (IRMIS) database.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Quock, D. E. R.; Cianciarulo, M. B.; APS Engineering Support Division

    2007-01-01

    The Integrated Relational Model of Installed Systems (IRMIS) is a relational database tool that has been implemented at the Advanced Photon Source to maintain an updated account of approximately 600 control system software applications, 400,000 process variables, and 30,000 control system hardware components. To effectively display this large amount of control system information to operators and engineers, IRMIS was initially built with nine Web-based viewers: Applications Organizing Index, IOC, PLC, Component Type, Installed Components, Network, Controls Spares, Process Variables, and Cables. However, since each viewer is designed to provide details from only one major category of the control system, themore » necessity for a one-stop global search tool for the entire database became apparent. The user requirements for extremely fast database search time and ease of navigation through search results led to the choice of Asynchronous JavaScript and XML (AJAX) technology in the implementation of the IRMIS global search tool. Unique features of the global search tool include a two-tier level of displayed search results, and a database data integrity validation and reporting mechanism.« less

  7. Process Management inside ATLAS DAQ

    NASA Astrophysics Data System (ADS)

    Alexandrov, I.; Amorim, A.; Badescu, E.; Burckhart-Chromek, D.; Caprini, M.; Dobson, M.; Duval, P. Y.; Hart, R.; Jones, R.; Kazarov, A.; Kolos, S.; Kotov, V.; Liko, D.; Lucio, L.; Mapelli, L.; Mineev, M.; Moneta, L.; Nassiakou, M.; Pedro, L.; Ribeiro, A.; Roumiantsev, V.; Ryabov, Y.; Schweiger, D.; Soloviev, I.; Wolters, H.

    2002-10-01

    The Process Management component of the online software of the future ATLAS experiment data acquisition system is presented. The purpose of the Process Manager is to perform basic job control of the software components of the data acquisition system. It is capable of starting, stopping and monitoring the status of those components on the data acquisition processors independent of the underlying operating system. Its architecture is designed on the basis of a server client model using CORBA based communication. The server part relies on C++ software agent objects acting as an interface between the local operating system and client applications. Some of the major design challenges of the software agents were to achieve the maximum degree of autonomy possible, to create processes aware of dynamic conditions in their environment and with the ability to determine corresponding actions. Issues such as the performance of the agents in terms of time needed for process creation and destruction, the scalability of the system taking into consideration the final ATLAS configuration and minimizing the use of hardware resources were also of critical importance. Besides the details given on the architecture and the implementation, we also present scalability and performance tests results of the Process Manager system.

  8. A single-component multidrug transporter of the major facilitator superfamily is part of a network that protects E scherichia coli from bile salt stress

    PubMed Central

    Paul, Stephanie; Alegre, Kamela O; Holdsworth, Scarlett R; Rice, Matthew; Brown, James A; McVeigh, Paul; Kelly, Sharon M; Law, Christopher J

    2014-01-01

    Resistance to high concentrations of bile salts in the human intestinal tract is vital for the survival of enteric bacteria such as E scherichia coli. Although the tripartite AcrAB–TolC efflux system plays a significant role in this resistance, it is purported that other efflux pumps must also be involved. We provide evidence from a comprehensive suite of experiments performed at two different pH values (7.2 and 6.0) that reflect pH conditions that E . coli may encounter in human gut that MdtM, a single-component multidrug resistance transporter of the major facilitator superfamily, functions in bile salt resistance in E . coli by catalysing secondary active transport of bile salts out of the cell cytoplasm. Furthermore, assays performed on a chromosomal ΔacrB mutant transformed with multicopy plasmid encoding MdtM suggested a functional synergism between the single-component MdtM transporter and the tripartite AcrAB–TolC system that results in a multiplicative effect on resistance. Substrate binding experiments performed on purified MdtM demonstrated that the transporter binds to cholate and deoxycholate with micromolar affinity, and transport assays performed on inverted vesicles confirmed the capacity of MdtM to catalyse electrogenic bile salt/H+ antiport. PMID:24684269

  9. Human operator performance of remotely controlled tasks: Teleoperator research conducted at NASA's George C. Marshall Space Flight Center. Executive summary

    NASA Technical Reports Server (NTRS)

    Shields, N., Jr.; Piccione, F.; Kirkpatrick, M., III; Malone, T. B.

    1982-01-01

    The combination of human and machine capabilities into an integrated engineering system which is complex and interactive interdisciplinary undertaking is discussed. Human controlled remote systems referred to as teleoperators, are reviewed. The human factors requirements for remotely manned systems are identified. The data were developed in three principal teleoperator laboratories and the visual, manipulator and mobility laboratories are described. Three major sections are identified: (1) remote system components, (2) human operator considerations; and (3) teleoperator system simulation and concept verification.

  10. Engineering the IOOS: A Conceptual Design and Conceptual Operations Plan

    NASA Astrophysics Data System (ADS)

    Lampel, M.; Hood, C.; Kleinert, J.; Morgan, R. A.; Morris, P.

    2007-12-01

    The Integrated Ocean Observing System is the United States component in a world wide effort to provide global coverage of the world's oceans using the Global Ocean Observing System (GOOS). The US contribution includes systems supporting three major IOOS components: the Observation Subsystem, the Modeling and Analysis Subsystem, and the Data Management and Communications (DMAC) Subsystem. The assets to be used in these subsystems include hundreds of existing satellite sensors, buoy arrays, water level monitoring networks, wave monitoring networks, specialized systems for commerce, such as the Physical Oceanographic Real-Time System (PORTS®), and health and safety monitoring systems such as NOAA's (National Oceanic and Atmospheric Administration) Harmful Algal Bloom Forecasting System for the Gulf of Mexico. Conceptual design addresses the interconnectivity of these systems, while Conceptual Operations provides understanding of the motivators for interconnectivity and a methodology for how useful products are created and distributed. This paper will report on the conceptual design and the concept of operations devleoped by the authors under contract to NOAA.

  11. Does warm debris dust stem from asteroid belts?

    NASA Astrophysics Data System (ADS)

    Geiler, Fabian; Krivov, Alexander V.

    2017-06-01

    Many debris discs reveal a two-component structure, with a cold outer and a warm inner component. While the former are likely massive analogues of the Kuiper belt, the origin of the latter is still a matter of debate. In this work, we investigate whether the warm dust may be a signature of asteroid belt analogues. In the scenario tested here, the current two-belt architecture stems from an originally extended protoplanetary disc, in which planets have opened a gap separating it into the outer and inner discs which, after the gas dispersal, experience a steady-state collisional decay. This idea is explored with an analytic collisional evolution model for a sample of 225 debris discs from a Spitzer/IRS catalogue that are likely to possess a two-component structure. We find that the vast majority of systems (220 out of 225, or 98 per cent) are compatible with this scenario. For their progenitors, original protoplanetary discs, we find an average surface density slope of -0.93 ± 0.06 and an average initial mass of (3.3^{+0.4}_{-0.3})× 10^{-3} solar masses, both of which are in agreement with the values inferred from submillimetre surveys. However, dust production by short-period comets and - more rarely - inward transport from the outer belts may be viable, and not mutually excluding, alternatives to the asteroid belt scenario. The remaining five discs (2 per cent of the sample: HIP 11486, HIP 23497, HIP 57971, HIP 85790, HIP 89770) harbour inner components that appear inconsistent with dust production in an 'asteroid belt.' Warm dust in these systems must either be replenished from cometary sources or represent an aftermath of a recent rare event, such as a major collision or planetary system instability.

  12. Multifunctional nanoparticles for drug/gene delivery in nanomedicine

    NASA Astrophysics Data System (ADS)

    Seale, Mary-Margaret; Zemlyanov, Dimitry; Cooper, Christy L.; Haglund, Emily; Prow, Tarl W.; Reece, Lisa M.; Leary, James F.

    2007-02-01

    Multifunctional nanoparticles hold great promise for drug/gene delivery. Multilayered nanoparticles can act as nanomedical systems with on-board "molecular programming" to accomplish complex multi-step tasks. For example, the targeting process has only begun when the nanosystem has found the correct diseased cell of interest. Then it must pass the cell membrane and avoid enzymatic destruction within the endosomes of the cell. Since the nanosystem is only about one millionth the volume of a human cell, for it to have therapeutic efficacy with its contained package, it must deliver that drug or gene to the appropriate site within the living cell. The successive de-layering of these nanosystems in a controlled fashion allows the system to accomplish operations that would be difficult or impossible to do with even complex single molecules. In addition, portions of the nanosystem may be protected from premature degradation or mistargeting to non-diseased cells. All of these problems remain major obstacles to successful drug delivery with a minimum of deleterious side effects to the patient. This paper describes some of the many components involved in the design of a general platform technology for nanomedical systems. The feasibility of most of these components has been demonstrated by our group and others. But the integration of these interacting sub-components remains a challenge. We highlight four components of this process as examples. Each subcomponent has its own sublevels of complexity. But good nanomedical systems have to be designed/engineered as a full nanomedical system, recognizing the need for the other components.

  13. 76 FR 5192 - BOEMRE Information Collection Activity: 1010-0170-Coastal Impact Assistance Program (CIAP...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... disclose this information, you should comment and provide your total capital and startup cost components or... use to estimate major cost factors, including system and technology acquisition, expected useful life... startup costs include, among other items, computers and software you purchase to prepare for collecting...

  14. ENHANCED ORGANIC MATTER REMINERALIZATION AND NUTRIENT TURNOVER BY BURROWING SHRIMP POPULATIONS IN YAQUINA BAY, OR

    EPA Science Inventory

    Burrowing thalassinid shrimp are major ecological components of Pacific Northwest (PNW) estuaries and where they structure large areas of intertidal and shallow subtidal habitat. These crustaceans occur in dense beds (>250 m-2) and dig extensive burrow systems (>1 m) controlling ...

  15. Implementing Technology: A Change Process

    ERIC Educational Resources Information Center

    Atwell, Nedra; Maxwell, Marge; Romero, Elizabeth

    2008-01-01

    The state of Kentucky has embarked upon a large scale systems change effort to integrate Universal Design for Learning (UDL) principles, including use of digital curriculum and computerized reading supports to improve overall student achievement. A major component of this initiative is the use of Read & Write Gold. As higher expectations are…

  16. Using vegetation indices as input into ramdom forest for soybean and weed classification

    USDA-ARS?s Scientific Manuscript database

    Weed management is a major component of a soybean (Glycine max L.) production system; thus, managers need tools to help them distinguish soybean from weeds. Vegetation indices derived from light reflectance properties of plants have shown promise as tools to enhance differences among plants. The o...

  17. Developing Flowcharted Procedures Manuals for School District Administration within the ISO 9000 Context.

    ERIC Educational Resources Information Center

    Schoch, Robert

    2002-01-01

    Describes how the School District of Lancaster, Pennsylvania, implemented a districtwide quality-management system based on the Geneva-based International Standards Organization 9001, a major component of which is the documentation of procedures. Includes sections on implementation, procedure manuals, quality management, uniformity, formatting,…

  18. Planning for the Automation of School Library Media Centers.

    ERIC Educational Resources Information Center

    Caffarella, Edward P.

    1996-01-01

    Geared for school library media specialists whose centers are in the early stages of automation or conversion to a new system, this article focuses on major components of media center automation: circulation control; online public access catalogs; machine readable cataloging; retrospective conversion of print catalog cards; and computer networks…

  19. Increasing Organizational Effectiveness through Better Human Resource Planning and Development

    ERIC Educational Resources Information Center

    Schein, Edgar H.

    1977-01-01

    Discusses the increasing importance of human resource planning and development for organizational effectiveness, and examines how the major components of a human resource planning and development system should be coordinated for maximum effectiveness. Available from Alfred P. Sloan School of Management, Massachusetts Institute of Technology,…

  20. Organic greenhouse soil media + supplemental fertilizer = better organic tomato transplants

    USDA-ARS?s Scientific Manuscript database

    Consumer perceptions that organic food tastes better and is healthier are two major factors driving the increasing demand for organically produced crops in the U.S. All components entering into the organic crop production system must be approved for organic use, including seed, soil media, and fert...

  1. Energy efficient engine component development and integration program

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The objective of the Energy Efficient Engine Component Development and Integration program is to develop, evaluate, and demonstrate the technology for achieving lower installed fuel consumption and lower operating costs in future commercial turbofan engines. Minimum goals have been set for a 12 percent reduction in thrust specific fuel consumption (TSFC), 5 percent reduction in direct operating cost (DOC), and 50 percent reduction in performance degradation for the Energy Efficient Engine (flight propulsion system) relative to the JT9D-7A reference engine. The Energy Efficienct Engine features a twin spool, direct drive, mixed flow exhaust configuration, utilizing an integrated engine nacelle structure. A short, stiff, high rotor and a single stage high pressure turbine are among the major enhancements in providing for both performance retention and major reductions in maintenance and direct operating costs. Improved clearance control in the high pressure compressor and turbines, and advanced single crystal materials in turbine blades and vanes are among the major features providing performance improvement. Highlights of work accomplished and programs modifications and deletions are presented.

  2. The role of complement in the success of vaccination with conjugated vs. unconjugated polysaccharide antigen.

    PubMed

    Salehen, Nur'ain; Stover, Cordula

    2008-01-24

    The complement system, a well-characterised arm of the innate immune system, significantly influences the adaptive immune response via direct cell-cell interaction and maintenance of lymphoid organ architecture. Development of vaccines is a major advance in modern health care. In this review, we highlight the importance of the marginal zone in response to both, polysaccharide and conjugated vaccines, and discuss the relevance of complement herein, based on findings obtained from animal models with specific deletions of certain complement components and from vaccination reports of complement-deficient individuals. We conclude that both, intactness of the complement system and maturity of expression of its components, are relatively more important to aid in the immune response to polysaccharide vaccine than to conjugated vaccines.

  3. In-Space Propulsion (ISP) Solar Sail Propulsion Technology Development

    NASA Technical Reports Server (NTRS)

    Montgomery, Edward E., IV

    2004-01-01

    An overview of the rationale and content for Solar Sail Propulsion (SSP), the on-going project to advance solar technology from technology readiness level 3 to 6 will be provided. A descriptive summary of the major and minor component efforts underway will include identification of the technology providers and a listing of anticipated products Recent important results from major system ground demonstrators will be provided. Finally, a current status of all activities will provided along with the most recent roadmap for the SSP technology development program.

  4. Fabrication and installation of the Solar Two central receiver

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Litwin, R.Z.; Rogers, R.D.

    The heart of the Solar Two power plant is the molten salt central receiver that has been designed, fabricated, and installed over an 18 month schedule. During this time, the receiver system from Solar One was also completely disassembled and removed. The receiver tower structure, for the most part, was left intact because Solar Two was designed to fit this structure such that construction time and costs could be minimized. In order to meet this aggressive schedule, receiver panel fabrication required the parallel production of many components. The sequence for assembly of the four major receiver panel components (i.e., tubes,more » header assembly, strongback, and header oven covers) and key fabrication activities such as welding are described. Once the receiver panels were complete, their installation at the site was begun, and the order in which receiver system components were installed in the tower is described. The completion of the Solar Two receiver proved the fabricability of this important system. However, successful operation of the system at Solar Two is needed to demonstrate the technical feasibility of the molten salt central receiver concept.« less

  5. A shared resource between declarative memory and motor memory.

    PubMed

    Keisler, Aysha; Shadmehr, Reza

    2010-11-03

    The neural systems that support motor adaptation in humans are thought to be distinct from those that support the declarative system. Yet, during motor adaptation changes in motor commands are supported by a fast adaptive process that has important properties (rapid learning, fast decay) that are usually associated with the declarative system. The fast process can be contrasted to a slow adaptive process that also supports motor memory, but learns gradually and shows resistance to forgetting. Here we show that after people stop performing a motor task, the fast motor memory can be disrupted by a task that engages declarative memory, but the slow motor memory is immune from this interference. Furthermore, we find that the fast/declarative component plays a major role in the consolidation of the slow motor memory. Because of the competitive nature of declarative and nondeclarative memory during consolidation, impairment of the fast/declarative component leads to improvements in the slow/nondeclarative component. Therefore, the fast process that supports formation of motor memory is not only neurally distinct from the slow process, but it shares critical resources with the declarative memory system.

  6. A shared resource between declarative memory and motor memory

    PubMed Central

    Keisler, Aysha; Shadmehr, Reza

    2010-01-01

    The neural systems that support motor adaptation in humans are thought to be distinct from those that support the declarative system. Yet, during motor adaptation changes in motor commands are supported by a fast adaptive process that has important properties (rapid learning, fast decay) that are usually associated with the declarative system. The fast process can be contrasted to a slow adaptive process that also supports motor memory, but learns gradually and shows resistance to forgetting. Here we show that after people stop performing a motor task, the fast motor memory can be disrupted by a task that engages declarative memory, but the slow motor memory is immune from this interference. Furthermore, we find that the fast/declarative component plays a major role in the consolidation of the slow motor memory. Because of the competitive nature of declarative and non-declarative memory during consolidation, impairment of the fast/declarative component leads to improvements in the slow/non-declarative component. Therefore, the fast process that supports formation of motor memory is not only neurally distinct from the slow process, but it shares critical resources with the declarative memory system. PMID:21048140

  7. Development of fine-resolution analyses and expanded large-scale forcing properties. Part II: Scale-awareness and application to single-column model experiments

    DOE PAGES

    Feng, Sha; Vogelmann, Andrew M.; Li, Zhijin; ...

    2015-01-20

    Fine-resolution three-dimensional fields have been produced using the Community Gridpoint Statistical Interpolation (GSI) data assimilation system for the U.S. Department of Energy’s Atmospheric Radiation Measurement Program (ARM) Southern Great Plains region. The GSI system is implemented in a multi-scale data assimilation framework using the Weather Research and Forecasting model at a cloud-resolving resolution of 2 km. From the fine-resolution three-dimensional fields, large-scale forcing is derived explicitly at grid-scale resolution; a subgrid-scale dynamic component is derived separately, representing subgrid-scale horizontal dynamic processes. Analyses show that the subgrid-scale dynamic component is often a major component over the large-scale forcing for grid scalesmore » larger than 200 km. The single-column model (SCM) of the Community Atmospheric Model version 5 (CAM5) is used to examine the impact of the grid-scale and subgrid-scale dynamic components on simulated precipitation and cloud fields associated with a mesoscale convective system. It is found that grid-scale size impacts simulated precipitation, resulting in an overestimation for grid scales of about 200 km but an underestimation for smaller grids. The subgrid-scale dynamic component has an appreciable impact on the simulations, suggesting that grid-scale and subgrid-scale dynamic components should be considered in the interpretation of SCM simulations.« less

  8. Improved E-ELT subsystem and component specifications, thanks to M1 test facility

    NASA Astrophysics Data System (ADS)

    Dimmler, M.; Marrero, J.; Leveque, S.; Barriga, Pablo; Sedghi, B.; Kornweibel, N.

    2014-07-01

    During the last 2 years ESO has operated the "M1 Test Facility", a test stand consisting of a representative section of the E-ELT primary mirror equipped with 4 complete prototype segment subunits including sensors, actuators and control system. The purpose of the test facility is twofold: it serves to study and get familiar with component and system aspects like calibration, alignment and handling procedures and suitable control strategies on real hardware long before the primary mirror (hereafter M1) components are commissioned. Secondly, and of major benefit to the project, it offered the possibility to evaluate component and subsystem performance and interface issues in a system context in such detail, that issues could be identified early enough to feed back into the subsystem and component specifications. This considerably reduces risk and cost of the production units and allows refocusing the project team on important issues for the follow-up of the production contracts. Experiences are presented in which areas the results of the M1 Test Facility particularly helped to improve subsystem specifications and areas, where additional tests were adopted independent of the main test facility. Presented are the key experiences of the M1 Test Facility which lead to improved specifications or identified the need for additional testing outside of the M1 Test Facility.

  9. Development of a software tool to support chemical and biological terrorism intelligence analysis

    NASA Astrophysics Data System (ADS)

    Hunt, Allen R.; Foreman, William

    1997-01-01

    AKELA has developed a software tool which uses a systems analytic approach to model the critical processes which support the acquisition of biological and chemical weapons by terrorist organizations. This tool has four major components. The first is a procedural expert system which describes the weapon acquisition process. It shows the relationship between the stages a group goes through to acquire and use a weapon, and the activities in each stage required to be successful. It applies to both state sponsored and small group acquisition. An important part of this expert system is an analysis of the acquisition process which is embodied in a list of observables of weapon acquisition activity. These observables are cues for intelligence collection The second component is a detailed glossary of technical terms which helps analysts with a non- technical background understand the potential relevance of collected information. The third component is a linking capability which shows where technical terms apply to the parts of the acquisition process. The final component is a simple, intuitive user interface which shows a picture of the entire process at a glance and lets the user move quickly to get more detailed information. This paper explains e each of these five model components.

  10. Independent Orbiter Assessment (IOA): Analysis of the active thermal control subsystem

    NASA Technical Reports Server (NTRS)

    Sinclair, S. K.; Parkman, W. E.

    1987-01-01

    The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA approach features a top-down analysis of the hardware to determine failure modes, criticality, and potential critical (PCIs) items. To preserve independence, this analysis was accomplished without reliance upon the results contained within the NASA FMEA/CIL documentation. The independent analysis results corresponding to the Orbiter Active Thermal Control Subsystem (ATCS) are documented. The major purpose of the ATCS is to remove the heat, generated during normal Shuttle operations from the Orbiter systems and subsystems. The four major components of the ATCS contributing to the heat removal are: Freon Coolant Loops; Radiator and Flow Control Assembly; Flash Evaporator System; and Ammonia Boiler System. In order to perform the analysis, the IOA process utilized available ATCS hardware drawings and schematics for defining hardware assemblies, components, and hardware items. Each level of hardware was evaluated and analyzed for possible failure modes and effects. Criticality was assigned based upon the severity of the effect for each failure mode. Of the 310 failure modes analyzed, 101 were determined to be PCIs.

  11. Using the ISS as a Testbed to Prepare for the Next Generation of Space-Based Telescopes

    NASA Technical Reports Server (NTRS)

    Ess, Kim; Thronson, Harley; Boyles, Mark; Sparks, William; Postman, Marc; Carpenter, Kenneth

    2012-01-01

    The ISS provides a unique opportunity to develop the technologies and operational capabilities necessary to assemble future large space telescopes that may be used to investigate planetary systems around neighboring stars. Assembling telescopes in space is a paradigm-shifting approach to space astronomy. Using the ISS as a testbed will reduce the technical risks of implementing this major scientific facility, such as laser metrology and wavefront sensing and control (WFSC). The Optical Testbed and Integration on ISS eXperiment (OpTIIX) will demonstrate the robotic assembly of major components, including the primary and secondary mirrors, to mechanical tolerances using existing ISS infrastructure, and the alignment of the optical elements to a diffraction-limited optical system in space. Assembling the optical system and removing and replacing components via existing ISS capabilities, such as the Special Purpose Dexterous Manipulator (SPDM) or the ISS flight crew, allows for future experimentation and repair, if necessary. First flight on ISS for OpTIIX, a small 1.5 meter optical telescope, is planned for 2015. In addition to demonstration of key risk-retiring technologies, the OpTIIX program includes a public outreach program to show the broad value of ISS utilization.

  12. LHC interaction region quadrupole cryostat design

    NASA Astrophysics Data System (ADS)

    Nicol, T. H.; Darve, Ch.; Huang, Y.; Page, T. M.

    2002-05-01

    The cryostat of a Large Hadron Collider (LHC) Interaction Region (IR) quadrupole magnet consists of all components of the inner triplet except the magnet assembly itself. It serves to support the magnet accurately and reliably within the vacuum vessel, to house all required cryogenic piping, and to insulate the cold mass from heat radiated and conducted from the environment. It must function reliably during storage, shipping and handling, normal magnet operation, quenches, and seismic excitations, and must be able to be manufactured at low cost. The major components of the cryostat are the vacuum vessel, thermal shield, multi-layer insulation system, cryogenic piping, and suspension system. The overall design of a cryostat for superconducting accelerator magnets requires consideration of fluid flow, proper selection of materials for their thermal and structural performance at both ambient and operating temperature, and knowledge of the environment to which the magnets will be subjected over the course of their expected operating lifetime. This paper describes the current LHC IR inner triplet quadrupole magnet cryostats being designed and manufactured at Fermilab as part of the US-LHC collaboration, and includes discussions on the structural and thermal considerations involved in the development of each of the major systems.

  13. LEGOS: Object-based software components for mission-critical systems. Final report, June 1, 1995--December 31, 1997

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1998-08-01

    An estimated 85% of the installed base of software is a custom application with a production quantity of one. In practice, almost 100% of military software systems are custom software. Paradoxically, the marginal costs of producing additional units are near zero. So why hasn`t the software market, a market with high design costs and low productions costs evolved like other similar custom widget industries, such as automobiles and hardware chips? The military software industry seems immune to market pressures that have motivated a multilevel supply chain structure in other widget industries: design cost recovery, improve quality through specialization, and enablemore » rapid assembly from purchased components. The primary goal of the ComponentWare Consortium (CWC) technology plan was to overcome barriers to building and deploying mission-critical information systems by using verified, reusable software components (Component Ware). The adoption of the ComponentWare infrastructure is predicated upon a critical mass of the leading platform vendors` inevitable adoption of adopting emerging, object-based, distributed computing frameworks--initially CORBA and COM/OLE. The long-range goal of this work is to build and deploy military systems from verified reusable architectures. The promise of component-based applications is to enable developers to snap together new applications by mixing and matching prefabricated software components. A key result of this effort is the concept of reusable software architectures. A second important contribution is the notion that a software architecture is something that can be captured in a formal language and reused across multiple applications. The formalization and reuse of software architectures provide major cost and schedule improvements. The Unified Modeling Language (UML) is fast becoming the industry standard for object-oriented analysis and design notation for object-based systems. However, the lack of a standard real-time distributed object operating system, lack of a standard Computer-Aided Software Environment (CASE) tool notation and lack of a standard CASE tool repository has limited the realization of component software. The approach to fulfilling this need is the software component factory innovation. The factory approach takes advantage of emerging standards such as UML, CORBA, Java and the Internet. The key technical innovation of the software component factory is the ability to assemble and test new system configurations as well as assemble new tools on demand from existing tools and architecture design repositories.« less

  14. Digital Avionics Information System (DAIS): Life Cycle Cost Impact Modeling System Reliability, Maintainability, and Cost Model (RMCM)--Description. Users Guide. Final Report.

    ERIC Educational Resources Information Center

    Goclowski, John C.; And Others

    The Reliability, Maintainability, and Cost Model (RMCM) described in this report is an interactive mathematical model with a built-in sensitivity analysis capability. It is a major component of the Life Cycle Cost Impact Model (LCCIM), which was developed as part of the DAIS advanced development program to be used to assess the potential impacts…

  15. Low cost attitude control system scanwheel development

    NASA Astrophysics Data System (ADS)

    Bialke, William; Selby, Vaughn

    1991-03-01

    In order to satisfy a growing demand for low cost attitude control systems for small spacecraft, development of low cost scanning horizon sensor coupled to a low cost/low power consumption Reaction Wheel Assembly was initiated. This report addresses the details of the versatile design resulting from this effort. Tradeoff analyses for each of the major components are included, as well as test data from an engineering prototype of the hardware.

  16. Low cost attitude control system scanwheel development

    NASA Technical Reports Server (NTRS)

    Bialke, William; Selby, Vaughn

    1991-01-01

    In order to satisfy a growing demand for low cost attitude control systems for small spacecraft, development of low cost scanning horizon sensor coupled to a low cost/low power consumption Reaction Wheel Assembly was initiated. This report addresses the details of the versatile design resulting from this effort. Tradeoff analyses for each of the major components are included, as well as test data from an engineering prototype of the hardware.

  17. United Stirling's Solar Engine Development: the Background for the Vanguard Engine

    NASA Technical Reports Server (NTRS)

    Holgersson, S.

    1984-01-01

    The development and testing resulting in the Vanguard engine and some of the characteristics of the Stirling engine based power conversion unit are described. The major part of the solar engine development is concentrated to the three different areas, the receiver, the lubrication system and the control system. Five engines are on test within the solar project. The function of the components are validated in actual solar tests.

  18. When 1+1 can be >2: Uncertainties compound when simulating climate, fisheries and marine ecosystems

    NASA Astrophysics Data System (ADS)

    Evans, Karen; Brown, Jaclyn N.; Sen Gupta, Alex; Nicol, Simon J.; Hoyle, Simon; Matear, Richard; Arrizabalaga, Haritz

    2015-03-01

    Multi-disciplinary approaches that combine oceanographic, biogeochemical, ecosystem, fisheries population and socio-economic models are vital tools for modelling whole ecosystems. Interpreting the outputs from such complex models requires an appreciation of the many different types of modelling frameworks being used and their associated limitations and uncertainties. Both users and developers of particular model components will often have little involvement or understanding of other components within such modelling frameworks. Failure to recognise limitations and uncertainties associated with components and how these uncertainties might propagate throughout modelling frameworks can potentially result in poor advice for resource management. Unfortunately, many of the current integrative frameworks do not propagate the uncertainties of their constituent parts. In this review, we outline the major components of a generic whole of ecosystem modelling framework incorporating the external pressures of climate and fishing. We discuss the limitations and uncertainties associated with each component of such a modelling system, along with key research gaps. Major uncertainties in modelling frameworks are broadly categorised into those associated with (i) deficient knowledge in the interactions of climate and ocean dynamics with marine organisms and ecosystems; (ii) lack of observations to assess and advance modelling efforts and (iii) an inability to predict with confidence natural ecosystem variability and longer term changes as a result of external drivers (e.g. greenhouse gases, fishing effort) and the consequences for marine ecosystems. As a result of these uncertainties and intrinsic differences in the structure and parameterisation of models, users are faced with considerable challenges associated with making appropriate choices on which models to use. We suggest research directions required to address these uncertainties, and caution against overconfident predictions. Understanding the full impact of uncertainty makes it clear that full comprehension and robust certainty about the systems themselves are not feasible. A key research direction is the development of management systems that are robust to this unavoidable uncertainty.

  19. Mission Report on the Orbiter Camera Payload System (OCPS) Large Format Camera (LFC) and Attitude Reference System (ARS)

    NASA Technical Reports Server (NTRS)

    Mollberg, Bernard H.; Schardt, Bruton B.

    1988-01-01

    The Orbiter Camera Payload System (OCPS) is an integrated photographic system which is carried into earth orbit as a payload in the Space Transportation System (STS) Orbiter vehicle's cargo bay. The major component of the OCPS is a Large Format Camera (LFC), a precision wide-angle cartographic instrument that is capable of producing high resolution stereo photography of great geometric fidelity in multiple base-to-height (B/H) ratios. A secondary, supporting system to the LFC is the Attitude Reference System (ARS), which is a dual lens Stellar Camera Array (SCA) and camera support structure. The SCA is a 70-mm film system which is rigidly mounted to the LFC lens support structure and which, through the simultaneous acquisition of two star fields with each earth-viewing LFC frame, makes it possible to determine precisely the pointing of the LFC optical axis with reference to the earth nadir point. Other components complete the current OCPS configuration as a high precision cartographic data acquisition system. The primary design objective for the OCPS was to maximize system performance characteristics while maintaining a high level of reliability compatible with Shuttle launch conditions and the on-orbit environment. The full-up OCPS configuration was launched on a highly successful maiden voyage aboard the STS Orbiter vehicle Challenger on October 5, 1984, as a major payload aboard mission STS 41-G. This report documents the system design, the ground testing, the flight configuration, and an analysis of the results obtained during the Challenger mission STS 41-G.

  20. Bidirectional neural interface: Closed-loop feedback control for hybrid neural systems.

    PubMed

    Chou, Zane; Lim, Jeffrey; Brown, Sophie; Keller, Melissa; Bugbee, Joseph; Broccard, Frédéric D; Khraiche, Massoud L; Silva, Gabriel A; Cauwenberghs, Gert

    2015-01-01

    Closed-loop neural prostheses enable bidirectional communication between the biological and artificial components of a hybrid system. However, a major challenge in this field is the limited understanding of how these components, the two separate neural networks, interact with each other. In this paper, we propose an in vitro model of a closed-loop system that allows for easy experimental testing and modification of both biological and artificial network parameters. The interface closes the system loop in real time by stimulating each network based on recorded activity of the other network, within preset parameters. As a proof of concept we demonstrate that the bidirectional interface is able to establish and control network properties, such as synchrony, in a hybrid system of two neural networks more significantly more effectively than the same system without the interface or with unidirectional alternatives. This success holds promise for the application of closed-loop systems in neural prostheses, brain-machine interfaces, and drug testing.

  1. A Reference Architecture for Space Information Management

    NASA Technical Reports Server (NTRS)

    Mattmann, Chris A.; Crichton, Daniel J.; Hughes, J. Steven; Ramirez, Paul M.; Berrios, Daniel C.

    2006-01-01

    We describe a reference architecture for space information management systems that elegantly overcomes the rigid design of common information systems in many domains. The reference architecture consists of a set of flexible, reusable, independent models and software components that function in unison, but remain separately managed entities. The main guiding principle of the reference architecture is to separate the various models of information (e.g., data, metadata, etc.) from implemented system code, allowing each to evolve independently. System modularity, systems interoperability, and dynamic evolution of information system components are the primary benefits of the design of the architecture. The architecture requires the use of information models that are substantially more advanced than those used by the vast majority of information systems. These models are more expressive and can be more easily modularized, distributed and maintained than simpler models e.g., configuration files and data dictionaries. Our current work focuses on formalizing the architecture within a CCSDS Green Book and evaluating the architecture within the context of the C3I initiative.

  2. A computer simulation of the turbocharged turbo compounded diesel engine system: A description of the thermodynamic and heat transfer models

    NASA Technical Reports Server (NTRS)

    Assanis, D. N.; Ekchian, J. E.; Frank, R. M.; Heywood, J. B.

    1985-01-01

    A computer simulation of the turbocharged turbocompounded direct-injection diesel engine system was developed in order to study the performance characteristics of the total system as major design parameters and materials are varied. Quasi-steady flow models of the compressor, turbines, manifolds, intercooler, and ducting are coupled with a multicylinder reciprocator diesel model, where each cylinder undergoes the same thermodynamic cycle. The master cylinder model describes the reciprocator intake, compression, combustion and exhaust processes in sufficient detail to define the mass and energy transfers in each subsystem of the total engine system. Appropriate thermal loading models relate the heat flow through critical system components to material properties and design details. From this information, the simulation predicts the performance gains, and assesses the system design trade-offs which would result from the introduction of selected heat transfer reduction materials in key system components, over a range of operating conditions.

  3. APDS: Autonomous Pathogen Detection System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Langlois, R G; Brown, S; Burris, L

    An early warning system to counter bioterrorism, the Autonomous Pathogen Detection System (APDS) continuously monitors the environment for the presence of biological pathogens (e.g., anthrax) and once detected, it sounds an alarm much like a smoke detector warns of a fire. Long before September 11, 2001, this system was being developed to protect domestic venues and events including performing arts centers, mass transit systems, major sporting and entertainment events, and other high profile situations in which the public is at risk of becoming a target of bioterrorist attacks. Customizing off-the-shelf components and developing new components, a multidisciplinary team developed APDS,more » a stand-alone system for rapid, continuous monitoring of multiple airborne biological threat agents in the environment. The completely automated APDS samples the air, prepares fluid samples in-line, and performs two orthogonal tests: immunoassay and nucleic acid detection. When compared to competing technologies, APDS is unprecedented in terms of flexibility and system performance.« less

  4. Energy storage and thermal control system design status

    NASA Technical Reports Server (NTRS)

    Simons, Stephen N.; Willhoite, Bryan C.; Vanommering, Gert

    1989-01-01

    The Space Station Freedom electric power system (EPS) will initially rely on photovoltaics for power generation and Ni/H2 batteries for electrical energy storage. The current design for and the development status of two major subsystems in the PV Power Module is discussed. The energy storage subsystem comprised of high capacity Ni/H2 batteries and the single-phase thermal control system that rejects the excess heat generated by the batteries and other components associated with power generation and storage is described.

  5. Human life support during interplanetary travel and domicile. VI - Generic modular flow schematic for hybrid physical/chemical-biological life support systems

    NASA Technical Reports Server (NTRS)

    Ganapathi, Gani B.; Seshan, P. K.; Ferrall, Joseph; Rohatgi, Naresh

    1992-01-01

    An extension is proposed for the NASA Space Exploration Initiative's Generic Modular Flow Schematics for physical/chemical life support systems which involves the addition of biological processes. The new system architecture includes plant, microbial, and animal habitat, as well as the human habitat subsystem. Major Feedstock Production and Food Preparation and Packaging components have also been incorporated. Inedible plant, aquaculture, microbial, and animal solids are processed for recycling.

  6. Energy storage and thermal control system design status. [for space station power supplies

    NASA Technical Reports Server (NTRS)

    Simons, Stephen N.; Willhoite, Bryan C.; Van Ommering, Gert

    1989-01-01

    The Space Station Freedom electric power system (EPS) will initially rely on photovoltaics for power generation and Ni/H2 batteries for electrical energy storage. The current design for the development status of two major subsystems in the PV Power Module is discussed. The energy storage subsystem comprised of high capacity Ni/H2 batteries and the single-phase thermal control system that rejects the excess heat generated by the batteries and other components associated with power generation andstorage is described.

  7. Availability analysis of an HTGR fuel recycle facility. Summary report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sharmahd, J.N.

    1979-11-01

    An availability analysis of reprocessing systems in a high-temperature gas-cooled reactor (HTGR) fuel recycle facility was completed. This report summarizes work done to date to define and determine reprocessing system availability for a previously planned HTGR recycle reference facility (HRRF). Schedules and procedures for further work during reprocessing development and for HRRF design and construction are proposed in this report. Probable failure rates, transfer times, and repair times are estimated for major system components. Unscheduled down times are summarized.

  8. A near-real-time full-parallax holographic display for remote operations

    NASA Technical Reports Server (NTRS)

    Iavecchia, Helene P.; Huff, Lloyd; Marzwell, Neville I.

    1991-01-01

    A near real-time, full parallax holographic display system was developed that has the potential to provide a 3-D display for remote handling operations in hazardous environments. The major components of the system consist of a stack of three spatial light modulators which serves as the object source of the hologram; a near real-time holographic recording material (such as thermoplastic and photopolymer); and an optical system for relaying SLM images to the holographic recording material and to the observer for viewing.

  9. Reactor moderator, pressure vessel, and heat rejection system of an open-cycle gas core nuclear rocket concept

    NASA Technical Reports Server (NTRS)

    Taylor, M. F.; Whitmarsh, C. L., Jr.; Sirocky, P. J., Jr.; Iwanczyke, L. C.

    1973-01-01

    A preliminary design study of a conceptual 6000-megawatt open-cycle gas-core nuclear rocket engine system was made. The engine has a thrust of 196,600 newtons (44,200 lb) and a specific impulse of 4400 seconds. The nuclear fuel is uranium-235 and the propellant is hydrogen. Critical fuel mass was calculated for several reactor configurations. Major components of the reactor (reflector, pressure vessel, and waste heat rejection system) were considered conceptually and were sized.

  10. A comparison of chemical, antioxidant and antimicrobial studies of cinnamon leaf and bark volatile oils, oleoresins and their constituents.

    PubMed

    Singh, Gurdip; Maurya, Sumitra; DeLampasona, M P; Catalan, Cesar A N

    2007-09-01

    The antioxidant, antifungal and antibacterial potentials of volatile oils and oleoresin of Cinnamomum zeylanicum Blume (leaf and bark) were investigated in the present study. The oleoresins have shown excellent activity for the inhibition of primary and secondary oxidation products in mustard oil added at the concentration of 0.02% which were evaluated using peroxide, thiobarbituric acid, p-anisidine and carbonyl values. Moreover, it was further supported by other complementary antioxidant assays such as ferric thiocyanate method in linoleic acid system, reducing power, chelating and scavenging effects on 1,1'-diphenyl-2-picrylhydrazyl (DPPH) and hydroxyl radicals. In antimicrobial investigations, using inverted petriplate and food poison techniques, the leaf and bark volatile oils has been found to be highly effective against all the tested fungi except Aspergillus ochraceus. However, leaf oleoresin has shown inhibition only for Penicillium citrinum whereas bark oleoresin has caused complete mycelial zone inhibition for Aspergillus flavus and A. ochraceus along with Aspergillus niger, Aspergillus terreus, P. citrinum and Penicillium viridicatum at 6 microL. Using agar well diffusion method, leaf volatile oil and oleoresin have shown better results in comparison with bark volatile oil, oleoresin and commercial bactericide, i.e., ampicillin. Gas chromatographic-mass spectroscopy studies on leaf volatile oil and oleoresin resulted in the identification of 19 and 25 components, which accounts for the 99.4% and 97.1%, respectively of the total amount and the major component was eugenol with 87.3% and 87.2%, respectively. The analysis of cinnamon bark volatile oil showed the presence of 13 components accounting for 100% of the total amount. (E)-cinnamaldehyde was found as the major component along with delta-cadinene (0.9%), whereas its bark oleoresin showed the presence of 17 components accounting for 92.3% of the total amount. The major components were (E)-cinnamaldehyde (49.9%), along with several other components.

  11. Membrane and Chaperone Recognition by the Major Translocator Protein PopB of the Type III Secretion System of Pseudomonas aeruginosa*

    PubMed Central

    Discola, Karen F.; Förster, Andreas; Boulay, François; Simorre, Jean-Pierre; Attree, Ina; Dessen, Andréa; Job, Viviana

    2014-01-01

    The type III secretion system is a widespread apparatus used by pathogenic bacteria to inject effectors directly into the cytoplasm of eukaryotic cells. A key component of this highly conserved system is the translocon, a pore formed in the host membrane that is essential for toxins to bypass this last physical barrier. In Pseudomonas aeruginosa the translocon is composed of PopB and PopD, both of which before secretion are stabilized within the bacterial cytoplasm by a common chaperone, PcrH. In this work we characterize PopB, the major translocator, in both membrane-associated and PcrH-bound forms. By combining sucrose gradient centrifugation experiments, limited proteolysis, one-dimensional NMR, and β-lactamase reporter assays on eukaryotic cells, we show that PopB is stably inserted into bilayers with its flexible N-terminal domain and C-terminal tail exposed to the outside. In addition, we also report the crystal structure of the complex between PcrH and an N-terminal region of PopB (residues 51–59), which reveals that PopB lies within the concave face of PcrH, employing mostly backbone residues for contact. PcrH is thus the first chaperone whose structure has been solved in complex with both type III secretion systems translocators, revealing that both molecules employ the same surface for binding and excluding the possibility of formation of a ternary complex. The characterization of the major type III secretion system translocon component in both membrane-bound and chaperone-bound forms is a key step for the eventual development of antibacterials that block translocon assembly. PMID:24297169

  12. Guide for Hydrogen Hazards Analysis on Components and Systems

    NASA Technical Reports Server (NTRS)

    Beeson, Harold; Woods, Stephen

    2003-01-01

    The physical and combustion properties of hydrogen give rise to hazards that must be considered when designing and operating a hydrogen system. One of the major concerns in the use of hydrogen is that of fire or detonation because of hydrogen's wide flammability range, low ignition energy, and flame speed. Other concerns include the contact and interaction of hydrogen with materials, such as the hydrogen embrittlement of materials and the formation of hydrogen hydrides. The low temperature of liquid and slush hydrogen bring other concerns related to material compatibility and pressure control; this is especially important when dissimilar, adjoining materials are involved. The potential hazards arising from these properties and design features necessitate a proper hydrogen hazards analysis before introducing a material, component, or system into hydrogen service. The objective of this guide is to describe the NASA Johnson Space Center White Sands Test Facility hydrogen hazards analysis method that should be performed before hydrogen is used in components and/or systems. The method is consistent with standard practices for analyzing hazards. It is recommended that this analysis be made before implementing a hydrogen component qualification procedure. A hydrogen hazards analysis is a useful tool for hydrogen-system designers, system and safety engineers, and facility managers. A hydrogen hazards analysis can identify problem areas before hydrogen is introduced into a system-preventing damage to hardware, delay or loss of mission or objective, and possible injury or loss of life.

  13. The secretory IgA system of lung secretions in chronic obstructive bronchitis: comparison of sputum with secretions obtained during fibreoptic bronchoscopy.

    PubMed Central

    Wiggins, J; Hill, S L; Stockley, R A

    1984-01-01

    The constituents of the secretory immunoglobulin A system (dimeric IgA, total secretory component and free secretory component) were measured in sputum sol phase, tracheal aspirates, and bronchoalveolar lavage fluids from 15 patients undergoing fibreoptic bronchoscopy. All of the proteins showed a progressive decrease in concentration from sputum to the bronchoalveolar lavage fluids (2p less than 0.001). Standardisation of samples by means of protein concentration ratios showed that all secretions were generally similar in respect of their secretory IgA profiles, although major differences remained in some individual patients. The between patient variability of the results was generally reduced by the use of protein concentration ratios, allowing closer comparison between subjects. When the secretion albumin concentration was used as a standard, however, it increased the variability of the sputum sol phase IgA components (2p less than 0.01), whereas it decreased the variability of the IgA components in the bronchoalveolar lavage fluid (2p less than 0.05). The role of albumin as a standard protein for assessing the secretory IgA system in lung secretions remains uncertain. PMID:6463931

  14. NASA-USRP Summer 2013 Internship Final Report

    NASA Technical Reports Server (NTRS)

    Gurganus, S. Christine

    2013-01-01

    Three major projects were undertaken during the Summer 2013 USRP Internship: (A) assisting the cTAPS group with component and pressure vessel system analyses and documentation, (B) designing a hoisting fixture for a solid rocket motor, (C) finding an alternative to removing the DOT rated gaseous nitrogen tank from the roof for hydrostatic testing. Hypergolic Material Assessments (HMAs) and pressure calculations were performed on components of pressure systems. Additionally, component information was logged in the Standard Parts Database to provide a location where system designers can find information regarding components, including their specifications and compatibility with fluids. A hoisting fixture was designed to hoist a solid rocket motor and meets the specifications related to stress and size. However, there are issues with the fixtures bolt head allotment, the bolt spacing, and the complexity of the part. Finally, calculations were performed on an expiring DOT rated gaseous nitrogen tank in an attempt to re-rate it per ASME standards. This was unsuccessful so other options are being explored for the tank. While much progress was made on all three projects, there is still work to be performed on each project to achieve the desired results.

  15. Formation of dominant mode by evolution in biological systems

    NASA Astrophysics Data System (ADS)

    Furusawa, Chikara; Kaneko, Kunihiko

    2018-04-01

    A reduction in high-dimensional phenotypic states to a few degrees of freedom is essential to understand biological systems. Here, we show evolutionary robustness causes such reduction which restricts possible phenotypic changes in response to a variety of environmental conditions. First, global protein expression changes in Escherichia coli after various environmental perturbations were shown to be proportional across components, across different types of environmental conditions. To examine if such dimension reduction is a result of evolution, we analyzed a cell model—with a huge number of components, that reproduces itself via a catalytic reaction network—and confirmed that common proportionality in the concentrations of all components is shaped through evolutionary processes. We found that the changes in concentration across all components in response to environmental and evolutionary changes are constrained to the changes along a one-dimensional major axis, within a huge-dimensional state space. On the basis of these observations, we propose a theory in which such constraints in phenotypic changes are achieved both by evolutionary robustness and plasticity and formulate this proposition in terms of dynamical systems. Accordingly, broad experimental and numerical results on phenotypic changes caused by evolution and adaptation are coherently explained.

  16. Retrofit photovoltaic systems for intermediate sized applications - A design and market study

    NASA Astrophysics Data System (ADS)

    Noel, G. T.; Hagely, J. R.

    An assessment of the technical and economic feasibility of retrofitting a significant portion of the existing intermediate sector building/application inventory with photovoltaic systems is presented. The assessment includes the development of detailed engineering and architectural designs as well as cost estimates for 12 representative installations. Promising applications include retail stores, warehouses, office buildings, religious buildings, shopping centers, education buildings, hospitals, and industrial sites. A market study indicates that there is a national invetory of 1.5 to 2.0 million feasible intermediate sector applications, with the majority being in the 20 to 400 kW size range. The present cost of the major systems components and the cost of necessary building modifications are the primary current barriers to the realization of a large retrofit photovoltaic system market. The development of standardized modular system designs and installation techniques are feasible ways to minimize costs.

  17. Object-oriented analysis and design of a health care management information system.

    PubMed

    Krol, M; Reich, D L

    1999-04-01

    We have created a prototype for a universal object-oriented model of a health care system compatible with the object-oriented approach used in version 3.0 of the HL7 standard for communication messages. A set of three models has been developed: (1) the Object Model describes the hierarchical structure of objects in a system--their identity, relationships, attributes, and operations; (2) the Dynamic Model represents the sequence of operations in time as a collection of state diagrams for object classes in the system; and (3) functional Diagram represents the transformation of data within a system by means of data flow diagrams. Within these models, we have defined major object classes of health care participants and their subclasses, associations, attributes and operators, states, and behavioral scenarios. We have also defined the major processes and subprocesses. The top-down design approach allows use, reuse, and cloning of standard components.

  18. Is it possible to re-establish pre-operative patellar kinematics using a ligament-balanced technique in total knee arthroplasty? A cadaveric investigation.

    PubMed

    Keshmiri, Armin; Springorum, Hans; Baier, Clemens; Zeman, Florian; Grifka, Joachim; Maderbacher, Günther

    2015-03-01

    Several authors emphasise that the appearance of patellar maltracking after total knee arthroplasty (TKA) is caused by rotational malalignment of the femoral and tibial components. Ligament-balanced femoral component rotation was not found to be associated with abnormal postoperative patellar position. We hypothesised that a ligament-balanced technique in TKA has the ability to best re-establish patellar kinematics. In ten cadaveric knees TKA was performed assessing femoral rotation in ligament-balanced and different femoral and tibial component rotation alignments. Patellar kinematics after different component rotations were analysed using a commercial computer navigation system. Ligament-balanced femoral rotation showed the best re-establishment of patellar kinematics after TKA compared to the healthy pre-operative knee. In contrast to tibial component rotation, femoral component rotation had a major impact on patellofemoral kinematics. This investigation suggests that a ligament-balanced technique in TKA is most likely to re-establish natural patellofemoral kinematics. Tibial component rotation did not influence patellar kinematics.

  19. Predicting the environmental impacts of chicken systems in the United Kingdom through a life cycle assessment: broiler production systems.

    PubMed

    Leinonen, I; Williams, A G; Wiseman, J; Guy, J; Kyriazakis, I

    2012-01-01

    The aim of this study was to apply the life cycle assessment (LCA) method, from cradle to gate, to quantify the environmental burdens per 1,000 kg of expected edible carcass weight in the 3 main broiler production systems in the United Kingdom: 1) standard indoor, 2) free range, and 3) organic, and to identify the main components of these burdens. The LCA method evaluates production systems logically to account for all inputs and outputs that cross a specified system boundary, and it relates these to the useful outputs. The analysis was based on an approach that applied a structural model for the UK broiler industry and mechanistic submodels for animal performance, crop production, and major nutrient flows. Simplified baseline feeds representative of those used by the UK broiler industry were used. Typical UK figures for performance and mortality of birds and farm energy and material use were applied. Monte Carlo simulations were used to quantify the uncertainties in the outputs. The length of the production cycle was longer for free-range and organic systems compared with that of the standard indoor system, and as a result, the feed consumption and manure production per bird were higher in the free-range and organic systems. These differences had a major effect on the differences in environmental burdens between the systems. Feed production, processing, and transport resulted in greater overall environmental impacts than any other components of broiler production; for example, 65 to 81% of the primary energy use and 71 to 72% of the global warming potential of the system were due to these burdens. Farm gas and oil use had the second highest impact in primary energy use (12-25%) followed by farm electricity use. The direct use of gas, oil, and electricity were generally lower in free-range and organic systems compared with their use in the standard indoor system. Manure was the main component of acidification potential and also had a relatively high eutrophication potential. The LCA method allows for comparisons between systems and for the identification of hotspots of environmental impacts that could be subject to mitigation.

  20. Sensitivities of projected 1980 photovoltaic system costs to major system cost drivers

    NASA Technical Reports Server (NTRS)

    Zimmerman, L. W.; Smith, J. L.

    1984-01-01

    The sensitivity of projected 1990 photovoltaic (PV) system costs to major system cost drivers was examined. It includes: (1) module costs and module efficiencies; (2) area related balance of system (BOS) costs; (3) inverter costs and efficiencies; and (4) module marketing and distribution markups and system integration fees. Recent PV system cost experiences and the high costs of electricity from the systems are reviewed. The 1990 system costs are projected for five classes of PV systems, including four ground mounted 5-MWp systems and one residential 5-kWp system. System cost projections are derived by first projecting costs and efficiencies for all subsystems and components. Sensitivity analyses reveal that reductions in module cost and engineering and system integration fees seem to have the greatest potential for contributing to system cost reduction. Although module cost is clearly the prime candidate for fruitful PV research and development activities, engineering and system integration fees seem to be more amenable to reduction through appropriate choice of system size and market strategy. Increases in inverter and module efficiency yield significant benefits, especially for systems with high area related costs.

  1. Core Community Specifications for Electron Microprobe Operating Systems: Software, Quality Control, and Data Management Issues

    NASA Technical Reports Server (NTRS)

    Fournelle, John; Carpenter, Paul

    2006-01-01

    Modem electron microprobe systems have become increasingly sophisticated. These systems utilize either UNIX or PC computer systems for measurement, automation, and data reduction. These systems have undergone major improvements in processing, storage, display, and communications, due to increased capabilities of hardware and software. Instrument specifications are typically utilized at the time of purchase and concentrate on hardware performance. The microanalysis community includes analysts, researchers, software developers, and manufacturers, who could benefit from exchange of ideas and the ultimate development of core community specifications (CCS) for hardware and software components of microprobe instrumentation and operating systems.

  2. Implementation of a system to provide mobile satellite services in North America

    NASA Technical Reports Server (NTRS)

    Johanson, Gary A.; Davies, N. George; Tisdale, William R. H.

    1993-01-01

    This paper describes the implementation of the ground network to support Mobile Satellite Services (MSS). The system is designed to take advantage of a powerful new satellite series and provides significant improvements in capacity and throughput over systems in service today. The system is described in terms of the services provided and the system architecture being implemented to deliver those services. The system operation is described including examples of a circuit switched and packet switched call placement. The physical architecture is presented showing the major hardware components and software functionality placement within the hardware.

  3. Observability of Plant Metabolic Networks Is Reflected in the Correlation of Metabolic Profiles.

    PubMed

    Schwahn, Kevin; Küken, Anika; Kliebenstein, Daniel J; Fernie, Alisdair R; Nikoloski, Zoran

    2016-10-01

    Understanding whether the functionality of a biological system can be characterized by measuring few selected components is key to targeted phenotyping techniques in systems biology. Methods from observability theory have proven useful in identifying sensor components that have to be measured to obtain information about the entire system. Yet, the extent to which the data profiles reflect the role of components in the observability of the system remains unexplored. Here we first identify the sensor metabolites in the model plant Arabidopsis (Arabidopsis thaliana) by employing state-of-the-art genome-scale metabolic networks. By using metabolic data profiles from a set of seven environmental perturbations as well as from natural variability, we demonstrate that the data profiles of sensor metabolites are more correlated than those of nonsensor metabolites. This pattern was confirmed with in silico generated metabolic profiles from a medium-size kinetic model of plant central carbon metabolism. Altogether, due to the small number of identified sensors, our study implies that targeted metabolite analyses may provide the vast majority of relevant information about plant metabolic systems. © 2016 American Society of Plant Biologists. All Rights Reserved.

  4. Issues and Methods for Assessing COTS Reliability, Maintainability, and Availability

    NASA Technical Reports Server (NTRS)

    Schneidewind, Norman F.; Nikora, Allen P.

    1998-01-01

    Many vendors produce products that are not domain specific (e.g., network server) and have limited functionality (e.g., mobile phone). In contrast, many customers of COTS develop systems that am domain specific (e.g., target tracking system) and have great variability in functionality (e.g., corporate information system). This discussion takes the viewpoint of how the customer can ensure the quality of COTS components. In evaluating the benefits and costs of using COTS, we must consider the environment in which COTS will operate. Thus we must distinguish between using a non-mission critical application like a spreadsheet program to produce a budget and a mission critical application like military strategic and tactical operations. Whereas customers will tolerate an occasional bug in the former, zero tolerance is the rule in the latter. We emphasize the latter because this is the arena where there are major unresolved problems in the application of COTS. Furthermore, COTS components may be embedded in the larger customer system. We refer to these as embedded systems. These components must be reliable, maintainable, and available, and must be with the larger system in order for the customer to benefit from the advertised advantages of lower development and maintenance costs. Interestingly, when the claims of COTS advantages are closely examined, one finds that to a great extent these COTS components consist of hardware and office products, not mission critical software [1]. Obviously, COTS components are different from custom components with respect to one or more of the following attributes: source, development paradigm, safety, reliability, maintainability, availability, security, and other attributes. However, the important question is whether they should be treated differently when deciding to deploy them for operational use; we suggest the answer is no. We use reliability as an example to justify our answer. In order to demonstrate its reliability, a COTS component must pass the same reliability evaluations as the custom components, otherwise the COTS components will be the weakest link in the chain of components and will be the determinant of software system reliability. The challenge is that there will be less information available for evaluating COTS components than for custom components but this does not mean we should despair and do nothing. Actually, there is a lot we can do even in the absence of documentation on COTS components because the customer will have information about how COTS components are to be used in the larger system. To illustrate our approach, we will consider the reliability, maintainability, and availability (RMA) of COTS components as used in larger systems. Finally, COTS suppliers might consider increasing visibility into their products to assist customers in determining the components' fitness for use in a particular application. We offer ideas of information that would be useful to customers, and what vendors might do to provide it.

  5. The Solutions Data Base Component of the Water Pollution Abatement Subsystem (WPAS) of the Pollution Abatement Management System. (PAMS).

    DTIC Science & Technology

    1981-04-01

    Facilities EngineerATTN: DAEN-MPC Fitzs ;mons Amy Medical Center ATTN: DAEN-PE Army Instl. and Major Activities (CONuS; waiter Reed Army Medical center ATTN...S)St. Paul Fort Sheridan 21st Support ComandTulsa Fort Stewart4 Vicksburg Fort Wainmright AN: AREA (5) Walls Walla Vancouver Bks. Wilmington US Am...ABG/DEEE Patrick AFB, FL 32925 ATTN: XRQ ’ C Bandy, John T. The Solutions Data Base component of the Water Pollution Abatement Subsystem (WPAS) of the

  6. NASP X-30 Propulsion technology status

    NASA Technical Reports Server (NTRS)

    Powell, William E.

    1992-01-01

    The performance goals of the NASP program require an aero-propulsion system with a high effective specific impulse. In order to achieve these goals, the high potential performance of air-breathing engines must be achieved over a very wide Mach number operating range. This, in turn, demands high component performance and involves many important technical issues which must be resolved. Scramjet Propulsion Technology is divided into five major areas: (1) inlets, (2) combustors, (3) nozzles, (4) component integration, and (5) test facilities. A status report covering the five areas is presented.

  7. Influence of polysaccharides on wine protein aggregation.

    PubMed

    Jaeckels, Nadine; Meier, Miriam; Dietrich, Helmut; Will, Frank; Decker, Heinz; Fronk, Petra

    2016-06-01

    Polysaccharides are the major high-molecular weight components of wines. In contrast, proteins occur only in small amounts in wine, but contribute to haze formation. The detailed mechanism of aggregation of these proteins, especially in combination with other wine components, remains unclear. This study demonstrates the different aggregation behavior between a buffer and a model wine system by dynamic light scattering. Arabinogalactan-protein, for example, shows an increased aggregation in the model wine system, while in the buffer system a reducing effect is observed. Thus, we could show the importance to examine the behavior of wine additives under conditions close to reality, instead of simpler buffer systems. Additional experiments on melting points of wine proteins reveal that only some isoforms of thaumatin-like proteins and chitinases are involved in haze formation. We can confirm interactions between polysaccharides and proteins, but none of these polysaccharides is able to prevent haze in wine. Copyright © 2016. Published by Elsevier Ltd.

  8. Cheetahs have a stronger constitutive innate immunity than leopards

    PubMed Central

    Heinrich, Sonja K.; Hofer, Heribert; Courtiol, Alexandre; Melzheimer, Jörg; Dehnhard, Martin; Czirják, Gábor Á.; Wachter, Bettina

    2017-01-01

    As a textbook case for the importance of genetics in conservation, absence of genetic variability at the major histocompatibility complex (MHC) is thought to endanger species viability, since it is considered crucial for pathogen resistance. An alternative view of the immune system inspired by life history theory posits that a strong response should evolve in other components of the immune system if there is little variation in the MHC. In contrast to the leopard (Panthera pardus), the cheetah (Acinonyx jubatus) has a relatively low genetic variability at the MHC, yet free-ranging cheetahs are healthy. By comparing the functional competence of the humoral immune system of both species in sympatric populations in Namibia, we demonstrate that cheetahs have a higher constitutive innate but lower induced innate and adaptive immunity than leopards. We conclude (1) immunocompetence of cheetahs is higher than previously thought; (2) studying both innate and adaptive components of immune systems will enrich conservation science. PMID:28333126

  9. Cheetahs have a stronger constitutive innate immunity than leopards.

    PubMed

    Heinrich, Sonja K; Hofer, Heribert; Courtiol, Alexandre; Melzheimer, Jörg; Dehnhard, Martin; Czirják, Gábor Á; Wachter, Bettina

    2017-03-23

    As a textbook case for the importance of genetics in conservation, absence of genetic variability at the major histocompatibility complex (MHC) is thought to endanger species viability, since it is considered crucial for pathogen resistance. An alternative view of the immune system inspired by life history theory posits that a strong response should evolve in other components of the immune system if there is little variation in the MHC. In contrast to the leopard (Panthera pardus), the cheetah (Acinonyx jubatus) has a relatively low genetic variability at the MHC, yet free-ranging cheetahs are healthy. By comparing the functional competence of the humoral immune system of both species in sympatric populations in Namibia, we demonstrate that cheetahs have a higher constitutive innate but lower induced innate and adaptive immunity than leopards. We conclude (1) immunocompetence of cheetahs is higher than previously thought; (2) studying both innate and adaptive components of immune systems will enrich conservation science.

  10. A dynamic case-based planning system for space station application

    NASA Technical Reports Server (NTRS)

    Oppacher, F.; Deugo, D.

    1988-01-01

    We are currently investigating the use of a case-based reasoning approach to develop a dynamic planning system. The dynamic planning system (DPS) is designed to perform resource management, i.e., to efficiently schedule tasks both with and without failed components. This approach deviates from related work on scheduling and on planning in AI in several aspects. In particular, an attempt is made to equip the planner with an ability to cope with a changing environment by dynamic replanning, to handle resource constraints and feedback, and to achieve some robustness and autonomy through plan learning by dynamic memory techniques. We briefly describe the proposed architecture of DPS and its four major components: the PLANNER, the plan EXECUTOR, the dynamic REPLANNER, and the plan EVALUATOR. The planner, which is implemented in Smalltalk, is being evaluated for use in connection with the Space Station Mobile Service System (MSS).

  11. Thermodynamic Database for the NdO(1.5)-YO(1.5)-YbO(1.5)-ScO(1.5)-ZrO2 System

    NASA Technical Reports Server (NTRS)

    Jacobson, Nathan S.; Copland, Evan H.; Kaufman, Larry

    2001-01-01

    A database for YO(1.5)-NdO(1.5)-YbO(1.5)-ScO(1.5)-ZrO2 for ThermoCalc (ThermoCalc AB, Stockholm, Sweden) has been developed. The basis of this work is the YO(1.5)-ZrO2 assessment by Y. Du, Z. Jin, and P. Huang, 'Thermodynamic Assessment of the ZrO2-YO(1.5) System'. Experimentally only the YO(1.5)-ZrO2 system has been well-studied. All other systems are only approximately known. The major simplification in this work is the treatment of each single cation unit as a component. The pure liquid oxides are taken as reference states and two term lattice stability descriptions are used for each of the components. The limited experimental phase diagrams are reproduced.

  12. Staphylococcus aureus Manipulates Innate Immunity through Own and Host-Expressed Proteases.

    PubMed

    Pietrocola, Giampiero; Nobile, Giulia; Rindi, Simonetta; Speziale, Pietro

    2017-01-01

    Neutrophils, complement system and skin collectively represent the main elements of the innate immune system, the first line of defense of the host against many common microorganisms. Bacterial pathogens have evolved strategies to counteract all these defense activities. Specifically, Staphylococcus aureus , a major human pathogen, secretes a variety of immune evasion molecules including proteases, which cleave components of the innate immune system or disrupt the integrity of extracellular matrix and intercellular connections of tissues. Additionally, S. aureus secretes proteins that can activate host zymogens which, in turn, target specific defense components. Secreted proteins can also inhibit the anti-bacterial function of neutrophils or complement system proteases, potentiating S. aureus chances of survival. Here, we review the current understanding of these proteases and modulators of host proteases in the functioning of innate immunity and describe the importance of these mechanisms in the pathology of staphylococcal diseases.

  13. Staphylococcus aureus Manipulates Innate Immunity through Own and Host-Expressed Proteases

    PubMed Central

    Pietrocola, Giampiero; Nobile, Giulia; Rindi, Simonetta; Speziale, Pietro

    2017-01-01

    Neutrophils, complement system and skin collectively represent the main elements of the innate immune system, the first line of defense of the host against many common microorganisms. Bacterial pathogens have evolved strategies to counteract all these defense activities. Specifically, Staphylococcus aureus, a major human pathogen, secretes a variety of immune evasion molecules including proteases, which cleave components of the innate immune system or disrupt the integrity of extracellular matrix and intercellular connections of tissues. Additionally, S. aureus secretes proteins that can activate host zymogens which, in turn, target specific defense components. Secreted proteins can also inhibit the anti-bacterial function of neutrophils or complement system proteases, potentiating S. aureus chances of survival. Here, we review the current understanding of these proteases and modulators of host proteases in the functioning of innate immunity and describe the importance of these mechanisms in the pathology of staphylococcal diseases. PMID:28529927

  14. The RAAF Logistics Study. Volume 3,

    DTIC Science & Technology

    human activity system which has been analysed by the Central Studies Establishment on behalf of the Defence Logistics Organisation. This work, now reported on, stems from a conviction that improved decision making can flow from an enhanced and integrated understanding of the activities necessary to fulfil the objectives of the system, by those involved in it or affected by it. This particular Volume deals with the description, using the Soft Systems Methodology described in Volume 1, of the RAAF Technical System which constitutes a major component of the overall RAAF

  15. Remote media vision-based computer input device

    NASA Astrophysics Data System (ADS)

    Arabnia, Hamid R.; Chen, Ching-Yi

    1991-11-01

    In this paper, we introduce a vision-based computer input device which has been built at the University of Georgia. The user of this system gives commands to the computer without touching any physical device. The system receives input through a CCD camera; it is PC- based and is built on top of the DOS operating system. The major components of the input device are: a monitor, an image capturing board, a CCD camera, and some software (developed by use). These are interfaced with a standard PC running under the DOS operating system.

  16. Liquid Rocket Booster (LRB) for the Space Transportation System (STS) systems study, volume 2

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The Liquid Rocket Booster (LRB) Systems Definition Handbook presents the analyses and design data developed during the study. The Systems Definition Handbook (SDH) contains three major parts: the LRB vehicles definition; the Pressure-Fed Booster Test Bed (PFBTB) study results; and the ALS/LRB study results. Included in this volume are the results of all trade studies; final configurations with supporting rationale and analyses; technology assessments; long lead requirements for facilities, materials, components, and subsystems; operational requirements and scenarios; and safety, reliability, and environmental analyses.

  17. X-Ray Imaging System

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The FluoroScan Imaging System is a high resolution, low radiation device for viewing stationary or moving objects. It resulted from NASA technology developed for x-ray astronomy and Goddard application to a low intensity x-ray imaging scope. FlouroScan Imaging Systems, Inc, (formerly HealthMate, Inc.), a NASA licensee, further refined the FluoroScan System. It is used for examining fractures, placement of catheters, and in veterinary medicine. Its major components include an x-ray generator, scintillator, visible light image intensifier and video display. It is small, light and maneuverable.

  18. Isotope Brayton space power systems and their technology

    NASA Technical Reports Server (NTRS)

    Schwartz, H.

    1972-01-01

    The objectives of the NASA Brayton Space Power Program and the advantages of achieving an isotope Brayton space power system are enumerated. The paper describes the 2-15 kWe Brayton engine, its subsystems, and major components and summarizes the status of the test program. Two areas of Brayton constituent technology are discussed-gas bearings and heat exchangers. A summary is given of a 500-2500 W isotope Brayton space power system study that showed very attractive performance, simplicity, and low cost for a system in this power range.

  19. International Space Station Major Constituent Analyzer On-orbit Performance

    NASA Technical Reports Server (NTRS)

    Gardner, Ben D.; Erwin, Phillip M.; Wiedemann, Rachel; Matty, Chris

    2016-01-01

    The Major Constituent Analyzer (MCA) is a mass spectrometer based system that measures the major atmospheric constituents on the International Space Station. A number of limited-life components require periodic change-out, including the ORU 02 analyzer and the ORU 08 Verification Gas Assembly. The most recent ORU 02 and ORU 08 assemblies are operating nominally. For ORU 02, the ion source filaments and ion pump lifetime continue to be key determinants of MCA performance. Additionally, testing is underway to evaluate the capacity of the MCA to analyze ammonia. Finally, plans are being made to bring the second MCA on ISS to an operational configuration.

  20. Optical computer switching network

    NASA Technical Reports Server (NTRS)

    Clymer, B.; Collins, S. A., Jr.

    1985-01-01

    The design for an optical switching system for minicomputers that uses an optical spatial light modulator such as a Hughes liquid crystal light valve is presented. The switching system is designed to connect 80 minicomputers coupled to the switching system by optical fibers. The system has two major parts: the connection system that connects the data lines by which the computers communicate via a two-dimensional optical matrix array and the control system that controls which computers are connected. The basic system, the matrix-based connecting system, and some of the optical components to be used are described. Finally, the details of the control system are given and illustrated with a discussion of timing.

  1. Modeling global change impacts on Northern Eurasia

    NASA Astrophysics Data System (ADS)

    Kicklighter, D. W.; Monier, E.; Sokolov, A. P.; Zhuang, Q.; Melillo, J. M.; Reilly, J. M.

    2016-12-01

    Northern Eurasia is a major player in the global carbon budget and includes roughly 70% of the Earth's boreal forest and more than two-thirds of the Earth's permafrost. The region has experienced dramatic climate change (increase in temperature, growing season length, floods and droughts), natural disturbances (wildfires and insect outbreaks), and land-use change (timber harvest, urbanization, expansion and abandonment of agricultural lands) over the past century. These large environmental and socioeconomic impacts have major implications for the carbon cycle in the region. Northern Eurasia is made up of a diverse set of ecosystems that range from deserts to forests, with significant areas of croplands, pastures, and urban areas. As such, it represents a complex system with substantial challenges for the modeling community. We provide an overview of past, ongoing and possible future efforts of the integrated modeling of global change for Northern Eurasia. First, we review the variety of existing modeling approaches to investigate specific components of Earth system dynamics in the region. While there are a limited number of studies that try to integrate various aspects of the Earth system through scale, teleconnections or processes, there are few systematic analyses of the various feedbacks among components within the Earth system. As a result, there is a lack of knowledge of the relative importance of such feedbacks, and it is unclear how relevant current studies, which do not account for these feedbacks, may be for policymaking. Next, we review the role of Earth system models, and their advantages/limitations compared to detailed single component models. We further introduce human activity models (e.g., global trade, economic models, demographic models), and the need for Integrated Assessment Models (IAMs), a suite of models that couple human activity models to Earth System Models. Finally, we examine emerging issues that require a representation of the coupled human/earth system models to address.

  2. Posttraumatic Stress Disorder: Five Vicious Cycles that Inhibit Effective Treatment.

    PubMed

    Ghaffarzadegan, Navid; Larson, Richard C

    2015-01-01

    Despite a wide range of studies and medical progress, it seems that we are far from significantly mitigating the problem of posttraumatic stress disorder (PTSD). The problem has major social and behavioral components. Developing innovative and effective policies requires a broad scope of analysis and consideration of the highly interconnected social, behavioral, and medical variables. In this article, we take a systems approach and offer an illustrative causal loop diagram which includes individual and social dynamics. Based on the map, we discuss 5 major barriers for effective interventions in PTSD. These barriers work as vicious cycles in the system, reduce effectiveness and therefore value of PTSD treatment. We also discuss policy implications of this perspective.

  3. Predictive ability of the Society for Vascular Surgery Wound, Ischemia, and foot Infection (WIfI) classification system after first-time lower extremity revascularizations.

    PubMed

    Darling, Jeremy D; McCallum, John C; Soden, Peter A; Guzman, Raul J; Wyers, Mark C; Hamdan, Allen D; Verhagen, Hence J; Schermerhorn, Marc L

    2017-03-01

    The Society for Vascular Surgery (SVS) Wound, Ischemia and foot Infection (WIfI) classification system was proposed to predict 1-year amputation risk and potential benefit from revascularization. Our goal was to evaluate the predictive ability of this scale in a real-world selection of patients undergoing a first-time lower extremity revascularization for chronic limb-threatening ischemia (CLTI). From 2005 to 2014, 1336 limbs underwent a first-time lower extremity revascularization for CLTI, of which 992 had sufficient data to classify all three WIfI components (wound, ischemia, and foot infection). Limbs were stratified into the SVS WIfI clinical stages (from 1 to 4) for 1-year amputation risk estimation, a novel WIfI composite score from 0 to 9 (that weighs all WIfI variables equally), and a novel WIfI mean score from 0 to 3 (that can incorporate limbs missing any of the three WIfI components). Outcomes included major amputation; revascularization, major amputation, or stenosis (>3.5× step-up by duplex; RAS) events; and death. Predictors were identified using Cox regression models and Kaplan-Meier survival estimates. Of the 1336 first-time procedures performed, 992 limbs were classified in all three WIfI components (524 endovascular and 468 bypass; 26% rest pain and 74% tissue loss). Cox regression demonstrated that a one-unit increase in the WIfI clinical stage increases the risk of major amputation (hazard ratio [HR], 2.4; 95% confidence interval [CI], 1.7-3.2) and RAS events in all limbs (HR, 1.2; 95% CI, 1.1-1.3). Separate models of the entire cohort, a bypass-only cohort, and an endovascular-only cohort showed that a one-unit increase in the WIfI mean score is associated with an increase in the risk of major amputation (all three cohorts: HR, 5.3 [95% CI, 3.6-6.8], 4.1 [2.4-6.9], and 6.6 [3.8-11.6], respectively) and RAS events (all three cohorts: HR, 1.7 [95% CI, 1.4-2.0], 1.9 [1.4-2.6], and 1.4 [1.1-1.9], respectively). The novel WIfI composite and WIfI mean scores were the only consistent predictors of death among the three cohorts, with the WIfI mean score proving most strongly predictive in the entire cohort (HR, 1.4; 95% CI, 1.1-1.7), the bypass-only cohort (HR, 1.5; 95% CI, 1.1-1.9), and the endovascular-only cohort (HR, 1.4; 95% CI, 1.0-1.8). Although the individual WIfI wound component was able to predict mortality among all patients (HR, 1.1; 95% CI, 1.0-1.2) and bypass-only patients (HR, 1.2; 95% CI, 1.1-1.3), neither the additional individual WIfI components nor the WIfI clinical stage were able to significantly predict mortality among any cohort. This study supports the ability of the SVS WIfI classification system to predict major amputation; however, the novel WIfI mean and WIfI composite scores predict amputation, RAS events, and mortality more consistently than any other current WIfI scoring system. The WIfI mean score allows inclusion of all limbs, and both novel scoring systems are easier to conceptualize, give equal weight to each WIfI component, and may provide clinicians more effective comparisons in outcomes between patients. Copyright © 2016 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

  4. SRB/SLEEC (Solid Rocket Booster/Shingle Lap Extendible Exit Cone) feasibility study, volume 2. Appendix A: Design study for a SLEEC actuation system

    NASA Technical Reports Server (NTRS)

    Thompson, D. S.

    1986-01-01

    The results are presented of a design feasibility study of a self-contained (powered) actuation system for a Shingle Lap Extendible Exit Cone (SLEEC) for Transportation System (STS). The evolution of the SLEEC actuation system design is reviewed, the final design concept is summarized, and the results of the detailed study of the final concept of the actuation system are treated. A conservative design using proven mechanical components was established as a major program priority. The final mechanical design has a very low development risk since the components, which consist of ballscrews, gearing, flexible shaft drives, and aircraft cables, have extensive aerospace applications and a history of proven reliability. The mathematical model studies have shown that little or no power is required to deploy the SLEEC actuation system because acceleration forces and internal pressure from the rocket plume provide the required energies. A speed control brake is incorporated in the design in order to control the rate of deployment.

  5. Client Functional Assessment Data as Management Information: Woodrow Wilson Rehabilitation Center's Management Information System

    PubMed Central

    Steidle, Ernest F.

    1983-01-01

    This paper describes the design of a functional assessment system, a component of a management information system (MIS) that supports a comprehensive rehabilitation facility. Products of the subsystem document the functional status of rehabilitation clients through process evaluation reporting and outcomes reporting. The purpose of this paper is to describe the design of this MIS component. The environment supported, the integration requirements and the needed development approach is unique, requiring significant input from health care professionals, medical informatics specialists, statisticians and program evaluators. Strategies for the implementation of the functional assessment system are the major results reported in this paper. They are most useful to the systems designer or management engineer in a human service delivery setting. MIS plan development, computer file structure and access methods, and approaches to scheduling applications is described. Finally, the development of functional status measures is discussed. Application of the methodologies described will facilitate similar efforts towards systems development in other human service delivery settings.

  6. A DDC Bibliography on Computers in Information Sciences. Volume I. Information Sciences Series.

    ERIC Educational Resources Information Center

    Defense Documentation Center, Alexandria, VA.

    The unclassified and unlimited bibliography compiles references dealing specifically with the role of computers in information sciences. The volume contains 249 annotated references grouped under two major headings: Time Shared, On-Line, and Real Time Systems, and Computer Components. The references are arranged in accesion number (AD-number)…

  7. Bully Proofing Your School: Creating a Positive Climate.

    ERIC Educational Resources Information Center

    Garrity, Carla; And Others

    1997-01-01

    This article identifies the components of school programs necessary for preventing physical or emotional "bullying." The need for a systems approach that places power with the "caring majority" and encourages the assertive use of prosocial interventions is stressed, along with the importance of training all school staff and non-bullying students.…

  8. Oral Human Immunoglobulin for Children with Autism and Gastrointestinal Dysfunction: A Prospective, Open-Label Study

    ERIC Educational Resources Information Center

    Schneider, Cindy K.; Melmed, Raun D.; Barstow, Leon E.; Enriquez, F. Javier; Ranger-Moore, James; Ostrem, James A.

    2006-01-01

    Immunoglobulin secretion onto mucosal surfaces is a major component of the mucosal immune system. We hypothesized that chronic gastrointestinal (GI) disturbances associated with autistic disorder (AD) may be due to an underlying deficiency in mucosal immunity, and that orally administered immunoglobulin would be effective in alleviating chronic GI…

  9. Airborne Visible Laser Optical Communications Program (AVLOC)

    NASA Technical Reports Server (NTRS)

    Ward, J. H.

    1975-01-01

    The design, development, and operation of airborne and ground-based laser communications and laser radar hardware is described in support of the Airborne Visible Laser Optical Communication program. The major emphasis is placed on the development of a highly flexible test bed for the evaluation of laser communications systems techniques and components in an operational environment.

  10. Observer Training Manual for the Changing Teacher Practice Study. Revised Manual.

    ERIC Educational Resources Information Center

    Barnes, Susan

    This observer training manual was developed as a central component of a research effort, Changing Teacher Practice (CTP), which was designed to increase the frequency of effective teaching behaviors and staff development strategies in an ongoing school system. The observations focused on two major aspects of classroom teaching--instruction and…

  11. Construction Mechanic, Engine Tune-Up II (Diesel), 8-8. Military Curriculum Materials for Vocational and Technical Education.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. National Center for Research in Vocational Education.

    This course, adapted from military curriculum materials for vocational and technical education, teaches students to restore diesel engine performance to the manufacturer's specifications through troubleshooting and analyzing diesel engine fuel systems and to make minor and major adjustments to those components that directly affect engine…

  12. Apollo experience report: Command and service module sequential events control subsystem

    NASA Technical Reports Server (NTRS)

    Johnson, G. W.

    1975-01-01

    The Apollo command and service module sequential events control subsystem is described, with particular emphasis on the major systems and component problems and solutions. The subsystem requirements, design, and development and the test and flight history of the hardware are discussed. Recommendations to avoid similar problems on future programs are outlined.

  13. Cost Analysis of CATV Components. Final Report.

    ERIC Educational Resources Information Center

    Weinberg, Gary

    A research study was conducted for the Office of Telecommunications Policy to determine the capital outlay and operating costs of community antenna television (CATV) systems. Six major tasks were undertaken: 1) the development of a body of technical information about CATV; 2) the production of a complete work breakdown structure; 3) a cost…

  14. Cover cropping frequency is the main driver of soil microbial changes during six years of organic vegetable production

    USDA-ARS?s Scientific Manuscript database

    Soil microbes play a key role in soil health, and understanding the functional role of this living component of soil organic matter is critical to developing sustainable systems in major vegetable production regions like Salinas, California. Soil microbial community size and composition was evaluat...

  15. Firestar-"D": Computerized Adaptive Testing Simulation Program for Dichotomous Item Response Theory Models

    ERIC Educational Resources Information Center

    Choi, Seung W.; Podrabsky, Tracy; McKinney, Natalie

    2012-01-01

    Computerized adaptive testing (CAT) enables efficient and flexible measurement of latent constructs. The majority of educational and cognitive measurement constructs are based on dichotomous item response theory (IRT) models. An integral part of developing various components of a CAT system is conducting simulations using both known and empirical…

  16. A Survey of State Policies on the Use of Medication in Schools.

    ERIC Educational Resources Information Center

    Courtnage, Lee

    1982-01-01

    A national survey was conducted to determine the existing legal authority of the 50 states concerning the administration and overall management of legally prescribed drugs in the school system and to delineate the major components contained in the statutes, promulgated regulations, opinions of attorneys general, and recommended guidelines. (SW)

  17. Geometric modeling for computer aided design

    NASA Technical Reports Server (NTRS)

    Schwing, James L.

    1988-01-01

    Research focused on two major areas. The first effort addressed the design and implementation of a technique that allows for the visualization of the real time variation of physical properties. The second effort focused on the design and implementation of an on-line help system with components designed for both authors and users of help information.

  18. Role- and Relationship-Based Identity Management for Privacy-Enhanced E-Learning

    ERIC Educational Resources Information Center

    Anwar, Mohd; Greer, Jim

    2012-01-01

    An e-learning discussion forum, an essential component of today's e-learning systems, offers a platform for social learning activities. However, as learners participate in the discussion forum, privacy emerges as a major concern. Privacy concerns in social learning activities originate from one learner's inability to convey a desired presentation…

  19. Modeling erosion from forest roads with WEPP

    Treesearch

    J. McFero Grace

    2007-01-01

    Forest roads can be major sources of soil erosion from forest watersheds. Sediments from forest roads are a concern due to their potential delivery to stream systems resulting in degradation of water quality. The Water Erosion Prediction Project (WEPP) was used to predict erosion from forest road components under different management practices. WEPP estimates are...

  20. Application of WEPP to a Southern Appalachian Forest road

    Treesearch

    Johnny M. Grace

    2005-01-01

    Forest roads can be major sources of sediment and soil erosion from southern Appalachian Mountain watersheds. Sediments from forest roads are a concern due to their potential delivery to stream systems resulting in degradation of water quality. Prediction of sediment yields from forest road components can provide valuable information in planning, locating, and...

  1. Effective Student Learning: By Implementing Three Major Components

    ERIC Educational Resources Information Center

    Rulloda, Rudolfo B.

    2010-01-01

    Over the past few years, the California educational system made the headlines in the newspapers, magazines, and radio stations describing the constant decline of our students' test scores, and the increasing number of Hispanic and African American students leaving California high schools. The public is asking why this is happening, and with the…

  2. Learning to Analyze and Code Accounting Transactions in Interactive Mode.

    ERIC Educational Resources Information Center

    Bentz, William F.; Ambler, Eric E.

    An interactive computer-assisted instructional (CAI) system, called CODE, is used to teach transactional analysis, or coding, in elementary accounting. The first major component of CODE is TEACH, a program which controls student input and output. Following the statement of a financial position on a cathode ray tube, TEACH describes an event to…

  3. ENDOR-Induced EPR of Disordered Systems: Application to X-Irradiated Alanine.

    PubMed

    Kusakovskij, Jevgenij; Maes, Kwinten; Callens, Freddy; Vrielinck, Henk

    2018-02-15

    The electron paramagnetic resonance (EPR) spectra of radiation-induced radicals in organic solids are generally composed of multiple components that largely overlap due to their similar weak g anisotropy and a large number of hyperfine (HF) interactions. Such properties make these systems difficult to study using standard cw EPR spectroscopy even in single crystals. Electron-nuclear double-resonance (ENDOR) spectroscopy is a powerful and widely used complementary technique. In particular, ENDOR-induced EPR (EIE) experiments are useful for separating the overlapping contributions. In the present work, these techniques were employed to study the EPR spectrum of stable radicals in X-irradiated alanine, which is widely used in dosimetric applications. The principal values of all major proton HF interactions of the dominant radicals were determined by analyzing the magnetic field dependence of the ENDOR spectrum at 50 K, where the rotation of methyl groups is frozen. Accurate simulations of the EPR spectrum were performed after the major components were separated using an EIE analysis. As a result, new evidence in favor of the model of the second dominant radical was obtained.

  4. Chemical composition of sedimentary rocks in California and Hawaii

    USGS Publications Warehouse

    Hill, Thelma P.

    1981-01-01

    A compilation of published chemical analyses of sedimentary rocks of the United States was undertaken by the U.S. Geological Survey in 1952 to make available scattered data that are needed for a wide range of economic and scientific uses. About 20,000-25,000 chemical analyses of sedimentary rocks in the United States have been published. This report brings together 2,312 of these analyses from California and Hawaii. The samples are arranged by general lithologic characteristics and locality. Indexes of stratigraphy, rock name, commercial uses, and minor elements are provided. The sedimentary rocks are classified into groups and into categories according to the chemical analyses. The groups (A through F2) are defined by a system similar to that proposed by Brian Mason in 1952, in which the main parameters are the three major components of sedimentary rocks: (1) uncombined silica, (2) clay (R203 ? 3Si02 ? nH20), and (3) calcium-magnesium carbonate. The categories are based on the degree of admixture of these three major components with other components, such as sulfate, phos- phate, and iron oxide. Common-rock, mixed-rock, and special-rock categories apply to rocks consisting of 85 percent or more, 50-84 percent, and less than 49 percent, respectively, of the three major components combined. Maps show distribution of sample localities by States; triangular diagrams show the lithologic characteristics and classification groups. Cumulative-frequency curves of each constituent in each classification group of the common-rock and mixed-rock categories are also included. The numerous analyses may not adequately represent the geochemical nature of the rock types and formations of the region because of sampling bias. Maps showing distribution of sample localities indicate that many of the localities are in areas where, for economic or other reasons, special problems attracted interest. Most of the analyzed rocks tended to be fairly simple in composition - mainly mixtures of just two of the three major components or a mixture of these and a fourth component such as phosphate, gypsum, or iron oxide.

  5. Analytical Components of the Benefits and Costs of the Clean Air Act 1990-2020, the Second Prospective Study

    EPA Pesticide Factsheets

    The major analytical components of the Second Prospective Study are shown on this page. For other major components of the study, supporting technical reports are available which provide additional technical information.

  6. A Proven Ground System Architecture for Promoting Collaboration and Common Solutions at NASA

    NASA Technical Reports Server (NTRS)

    Smith, Danford

    2005-01-01

    Requirement: Improve how NASA develops and maintains ground data systems for dozens of missions, with a couple new missions always in the development phase. Decided in 2001 on enhanced message-bus architecture. Users offered choices for major components. They plug and play because key interfaces are all the same. Can support COTS, heritage, and new software. Even the middleware can be switched. Project name: GMSEC. Goddard Mission Services Evolution Center.

  7. The NASA LeRC regenerative fuel cell system testbed program for goverment and commercial applications

    NASA Astrophysics Data System (ADS)

    Maloney, Thomas M.; Prokopius, Paul R.; Voecks, Gerald E.

    1995-01-01

    The Electrochemical Technology Branch of the NASA Lewis Research Center (LeRC) has initiated a program to develop a renewable energy system testbed to evaluate, characterize, and demonstrate fully integrated regenerative fuel cell (RFC) system for space, military, and commercial applications. A multi-agency management team, led by NASA LeRC, is implementing the program through a unique international coalition which encompasses both government and industry participants. This open-ended teaming strategy optimizes the development for space, military, and commercial RFC system technologies. Program activities to date include system design and analysis, and reactant storage sub-system design, with a major emphasis centered upon testbed fabrication and installation and testing of two key RFC system components, namely, the fuel cells and electrolyzers. Construction of the LeRC 25 kW RFC system testbed at the NASA-Jet Propulsion Labortory (JPL) facility at Edwards Air Force Base (EAFB) is nearly complete and some sub-system components have already been installed. Furthermore, planning for the first commercial RFC system demonstration is underway.

  8. Role of polysaccharides in food, digestion, and health

    PubMed Central

    Lovegrove, A.; Edwards, C. H.; De Noni, I.; Patel, H.; El, S. N.; Grassby, T.; Zielke, C.; Ulmius, M.; Nilsson, L.; Butterworth, P. J.; Ellis, P. R; Shewry, P. R.

    2017-01-01

    ABSTRACT Polysaccharides derived from plant foods are major components of the human diet, with limited contributions of related components from fungal and algal sources. In particular, starch and other storage carbohydrates are the major sources of energy in all diets, while cell wall polysaccharides are the major components of dietary fiber. We review the role of these components in the human diet, including their structure and distribution, their modification during food processing and effects on functional properties, their behavior in the gastrointestinal tract, and their contribution to healthy diets. PMID:25921546

  9. Role of polysaccharides in food, digestion, and health.

    PubMed

    Lovegrove, A; Edwards, C H; De Noni, I; Patel, H; El, S N; Grassby, T; Zielke, C; Ulmius, M; Nilsson, L; Butterworth, P J; Ellis, P R; Shewry, P R

    2017-01-22

    Polysaccharides derived from plant foods are major components of the human diet, with limited contributions of related components from fungal and algal sources. In particular, starch and other storage carbohydrates are the major sources of energy in all diets, while cell wall polysaccharides are the major components of dietary fiber. We review the role of these components in the human diet, including their structure and distribution, their modification during food processing and effects on functional properties, their behavior in the gastrointestinal tract, and their contribution to healthy diets.

  10. The mechanism of signal transduction by two-component systems.

    PubMed

    Casino, Patricia; Rubio, Vicente; Marina, Alberto

    2010-12-01

    Two-component systems, composed of a homodimeric histidine kinase (HK) and a response regulator (RR), are major signal transduction devices in bacteria. Typically the signal triggers HK autophosphorylation at one His residue, followed by phosphoryl transfer from the phospho-His to an Asp residue in the RR. Signal extinction frequently involves phospho-RR dephosphorylation by a phosphatase activity of the HK. Our understanding of these reactions and of the determinants of partner specificity among HK-RR couples has been greatly increased by recent crystal structures and biochemical experiments on HK-RR complexes. Cis-autophosphorylation (one subunit phosphorylates itself) occurs in some HKs while trans-autophosphorylation takes place in others. We review and integrate this new information, discuss the mechanism of the three reactions and propose a model for transmembrane signaling by these systems. Copyright © 2010 Elsevier Ltd. All rights reserved.

  11. DC current distribution mapping system of the solar panels using a HTS-SQUID gradiometer

    NASA Astrophysics Data System (ADS)

    Miyazaki, Shingo; Kasuya, Syohei; Mawardi Saari, Mohd; Sakai, Kenji; Kiwa, Toshihiko; Tsukamoto, Akira; Adachi, Seiji; Tanabe, Keiichi; Tsukada, Keiji

    2014-05-01

    Solar panels are expected to play a major role as a source of sustainable energy. In order to evaluate solar panels, non-destructive tests, such as defect inspections and response property evaluations, are necessary. We developed a DC current distribution mapping system of the solar panels using a High Critical Temperature Superconductor Superconducting Quantum Interference Device (HTS-SQUID) gradiometer with ramp edge type Josephson junctions. Two independent components of the magnetic fields perpendicular to the panel surface (∂Bz/∂x, ∂Bz/∂y) were detected. The direct current of the solar panel is visualized by calculating the composition of the two signal components, the phase angle, and mapping the DC current vector. The developed system can evaluate the uniformity of DC current distributions precisely and may be applicable for defect detection of solar panels.

  12. Genes of the antioxidant system of the honey bee: annotation and phylogeny.

    PubMed

    Corona, M; Robinson, G E

    2006-10-01

    Antioxidant enzymes perform a variety of vital functions including the reduction of life-shortening oxidative damage. We used the honey bee genome sequence to identify the major components of the honey bee antioxidant system. A comparative analysis of honey bee with Drosophila melanogaster and Anopheles gambiae shows that although the basic components of the antioxidant system are conserved, there are important species differences in the number of paralogs. These include the duplication of thioredoxin reductase and the expansion of the thioredoxin family in fly; lack of expansion of the Theta, Delta and Omega GST classes in bee and no expansion of the Sigma class in dipteran species. The differential expansion of antioxidant gene families among honey bees and dipteran species might reflect the marked differences in life history and ecological niches between social and solitary species.

  13. Optimization of replacement and inspection decisions for multiple components on a power system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mauney, D.A.

    1994-12-31

    The use of optimization on the rescheduling of replacement dates provided a very proactive approach to deciding when components on individual units need to be addressed with a run/repair/replace decision. Including the effects of time value of money and taxes and unit need inside the spreadsheet model allowed the decision maker to concentrate on the effects of engineering input and replacement date decisions on the final net present value (NPV). The personal computer (PC)-based model was applied to a group of 140 forced outage critical fossil plant tube components across a power system. The estimated resulting NPV of the optimizationmore » was in the tens of millions of dollars. This PC spreadsheet model allows the interaction of inputs from structural reliability risk assessment models, plant foreman interviews, and actual failure history on a by component by unit basis across a complete power production system. This model includes not only the forced outage performance of these components caused by tube failures but, in addition, the forecasted need of the individual units on the power system and the expected cost of their replacement power if forced off line. The use of cash flow analysis techniques in the spreadsheet model results in the calculation of an NPV for a whole combination of replacement dates. This allows rapid assessments of {open_quotes}what if{close_quotes} scenarios of major maintenance projects on a systemwide basis and not just on a unit-by-unit basis.« less

  14. Heterogeneous ligand-nanoparticle distributions: a major obstacle to scientific understanding and commercial translation.

    PubMed

    Mullen, Douglas G; Banaszak Holl, Mark M

    2011-11-15

    Nanoparticles conjugated with functional ligands are expected to have a major impact in medicine, photonics, sensing, and nanoarchitecture design. One major obstacle to realizing the promise of these materials, however, is the difficulty in controlling the ligand/nanoparticle ratio. This obstacle can be segmented into three key areas: First, many designs of these systems have failed to account for the true heterogeneity of ligand/nanoparticle ratios that compose each material. Second, studies in the field often use the mean ligand/nanoparticle ratio as the accepted level of characterization of these materials. This measure is insufficient because it does not provide information about the distribution of ligand/nanoparticle species within a sample or the number and relative amount of the different species that compose a material. Without these data, researchers do not have an accurate definition of material composition necessary both to understand the material-property relationships and to monitor the consistency of the material. Third, some synthetic approaches now in use may not produce consistent materials because of their sensitivity to reaction kinetics and to the synthetic history of the nanoparticle. In this Account, we describe recent advances that we have made in under standing the material composition of ligand-nanoparticle systems. Our work has been enabled by a model system using poly(amidoamine) dendrimers and two small molecule ligands. Using reverse phase high-pressure liquid chromatography (HPLC), we have successfully resolved and quantified the relative amounts and ratios of each ligand/dendrimer combination. This type of information is rare within the field of ligand-nanoparticle materials because most analytical techniques have been unable to identify the components in the distribution. Our experimental data indicate that the actual distribution of ligand-nanoparticle components is much more heterogeneous than is commonly assumed. The mean ligand/nanoparticle ratio that is typically the only information known about a material is insufficient because the mean does not provide information on the diversity of components in the material and often does not describe the most common component (the mode). Additionally, our experimental data has provided examples of material batches with the same mean ligand/nanoparticle ratio and very different distributions. This discrepancy indicates that the mean cannot be used as the sole metric to assess the reproducibility of a system. We further found that distribution profiles can be highly sensitive to the synthetic history of the starting material as well as slight changes in reaction conditions. We have incorporated the lessons from our experimental data into the design of new ligand-nanoparticle systems to provide improved control over these ratios.

  15. Advanced expander test bed program

    NASA Technical Reports Server (NTRS)

    Riccardi, D. P.; Mitchell, J. C.

    1993-01-01

    The Advanced Expander Test Bed (AETB) is a key element in NASA's Space Chemical Engine Technology Program for development and demonstration of expander cycle oxygen/hydrogen engine and advanced component technologies applicable to space engines as well as launch vehicle upper stage engines. The AETB will be used to validate the high-pressure expander cycle concept, investigate system interactions, and conduct investigations of advanced mission focused components and new health monitoring techniques in an engine system environment. The split expander cycle AETB will operate at combustion chamber pressures up to 1200 psia with propellant flow rates equivalent to 20,000 lbf vacuum thrust. Contract work began 27 Apr. 1990. During 1992, a major milestone was achieved with the review of the final design of the oxidizer turbopump in Sep. 1992.

  16. Membrane lipids and the origin of life

    NASA Technical Reports Server (NTRS)

    Oro, J.; Holzer, G.; Rao, M.; Tornabene, T. G.

    1981-01-01

    The current state of knowledge regarding the development of biological systems is briefly reviewed. At a crucial stage concerning the evolution of such systems, the mechanisms leading to more complex structures must have evolved within the confines of a protected microenvironment, similar to those provided by the contemporary cell membranes. The major components found normally in biomembranes are phospholipids. The structure of the biomembrane is examined, and attention is given to questions concerning the availability of the structural components which are necessary in the formation of primitive lipid membranes. Two approaches regarding the study of protomembranes are discussed. The probability of obtaining ether lipids under prebiotic conditions is considered, taking into account the formation of cyclic and acyclic isoprenoids by the irradiation of isoprene with UV.

  17. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mohamed Abdelrahman; roger Haggard; Wagdy Mahmoud

    The final goal of this project was the development of a system that is capable of controlling an industrial process effectively through the integration of information obtained through intelligent sensor fusion and intelligent control technologies. The industry of interest in this project was the metal casting industry as represented by cupola iron-melting furnaces. However, the developed technology is of generic type and hence applicable to several other industries. The system was divided into the following four major interacting components: 1. An object oriented generic architecture to integrate the developed software and hardware components @. Generic algorithms for intelligent signal analysismore » and sensor and model fusion 3. Development of supervisory structure for integration of intelligent sensor fusion data into the controller 4. Hardware implementation of intelligent signal analysis and fusion algorithms« less

  18. Thermoelectric Energy Conversion: Future Directions and Technology Development Needs

    NASA Technical Reports Server (NTRS)

    Fleurial, Jean-Pierre

    2007-01-01

    This viewgraph presentation reviews the process of thermoelectric energy conversion along with key technology needs and challenges. The topics include: 1) The Case for Thermoelectrics; 2) Advances in Thermoelectrics: Investment Needed; 3) Current U.S. Investment (FY07); 4) Increasing Thermoelectric Materials Conversion Efficiency Key Science Needs and Challenges; 5) Developing Advanced TE Components & Systems Key Technology Needs and Challenges; 6) Thermoelectrics; 7) 200W Class Lightweight Portable Thermoelectric Generator; 8) Hybrid Absorption Cooling/TE Power Cogeneration System; 9) Major Opportunities in Energy Industry; 10) Automobile Waste Heat Recovery; 11) Thermoelectrics at JPL; 12) Recent Advances at JPL in Thermoelectric Converter Component Technologies; 13) Thermoelectrics Background on Power Generation and Cooling Operational Modes; 14) Thermoelectric Power Generation; and 15) Thermoelectric Cooling.

  19. A Case Study of a Low Powervapour Compression Refrigeration System

    NASA Astrophysics Data System (ADS)

    Abinav, R.; Nambiar, G. K.; Sahu, Debjyoti

    2016-09-01

    Reported in this paper is a case study on a normal vapor compression refrigeration system which is expected to be run by photovoltaic panels to utilize minimum grid power. A small 120 W refrigerator is fabricated out of commercially available components and run by an inverter and battery connected to solar photovoltaic panel as well as grid. Temperature at several points was measured and the performance was evaluated. The Coefficient of performance (COP) to run such refrigerator is estimated after numerical simulation of major components namely, evaporator, condenser and a capillary tube. The simulation was done to obtain an effective cooling temperature and the results were compared with measured temperatures. Calculation proves to be in conformity with the actual model.

  20. Lunar base heat pump, phase 1

    NASA Technical Reports Server (NTRS)

    Goldman, Jeffrey H.; Harvey, A.; Lovell, T.; Walker, David H.

    1994-01-01

    This report describes the Phase 1 process and analysis used to select a refrigerant and thermodynamic cycle as the basis of a vapor compression heat pump requiring a high temperature lift, then to perform a preliminary design to implement the selected concept, including major component selection. Use of a vapor compression heat pump versus other types was based on prior work performed for the Electric Power Research Institute. A high lift heat pump is needed to enable a thermal control system to remove heat down to 275 K from a habitable volume when the external thermal environment is severe. For example, a long-term lunar base habitat will reject heat from a space radiator to a 325 K environment. The first step in the selection process was to perform an optimization trade study, quantifying the effect of radiator operating temperature and heat pump efficiency on total system mass; then, select the radiator operating temperature corresponding to the lowest system mass. Total system mass included radiators, all heat pump components, and the power supply system. The study showed that lunar night operation, with no temperature lift, dictated the radiator size. To operate otherwise would require a high mass penalty to store power. With the defined radiation surface, and heat pump performances assumed to be from 40 percent to 60 percent of the Carnot ideal, the optimum heat rejection temperature ranged from 387 K to 377 K, as a function of heat pump performance. Refrigerant and thermodynamic cycles were then selected to best meet the previously determined design conditions. The system was then adapted as a ground-based prototype lifting temperature to 360 K (versus 385 K for flight unit) and using readily available commercial-grade components. Over 40 refrigerants, separated into wet and dry compression behavioral types, were considered in the selection process. Refrigerants were initially screened for acceptable critical temperature. The acceptable refrigerants were analyzed in ideal single and two-stage thermodynamic cycles. Top candidates were analyzed assuming realistic component limits and system pressure drops, and were evaluated for other considerations such as safety, environmental impact, and commercial availability. A maximum coefficient of performance (COP) of 56 percent of the Carnot ideal was achievable for a three-stage CFC-11 cycle operating under the flight conditions above. The program was completed by defining a control scheme and by researching and selecting the major components, compressor and heat exchangers, that could be used to implement the thermodynamic cycle selected. Special attention was paid to using similar technologies for the SIRF and flight heat pumps resulting in the commercially available equivalent of the flight unit. A package concept was generated for the components selected and mass and volume estimated.

  1. The role of the immune system in Alzheimer disease: Etiology and treatment.

    PubMed

    Jevtic, Stefan; Sengar, Ameet S; Salter, Michael W; McLaurin, JoAnne

    2017-11-01

    The immune system is now considered a major factor in Alzheimer Disease (AD). This review seeks to demonstrate how various aspects of the immune system, both in the brain and peripherally, interact to contribute to AD. We highlight classical nervous system immune components, such as complement and microglia, as well as novel aspects of the peripheral immune system that can influence disease, such as monocytes and lymphocytes. By detailing the roles of various immune cells in AD, we summarize an emerging perspective for disease etiology and future therapeutic targets. Copyright © 2017. Published by Elsevier B.V.

  2. Working on the Boundaries: Philosophies and Practices of the Design Process

    NASA Technical Reports Server (NTRS)

    Ryan, R.; Blair, J.; Townsend, J.; Verderaime, V.

    1996-01-01

    While systems engineering process is a program formal management technique and contractually binding, the design process is the informal practice of achieving the design project requirements throughout all design phases of the systems engineering process. The design process and organization are systems and component dependent. Informal reviews include technical information meetings and concurrent engineering sessions, and formal technical discipline reviews are conducted through the systems engineering process. This paper discusses and references major philosophical principles in the design process, identifies its role in interacting systems and disciplines analyses and integrations, and illustrates the process application in experienced aerostructural designs.

  3. KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, one of two orbital maneuvering system (OMS) pods removed from Endeavour is lowered toward a transporter. The OMS pods are attached to the upper aft fuselage left and right sides. Fabricated primarily of graphite epoxy composite and aluminum, each pod is 21.8 feet long and 11.37 feet wide at its aft end and 8.41 feet wide at its forward end, with a surface area of approximately 435 square feet. Each pod houses the Reaction Control System propulsion components used for inflight maneuvering and is attached to the aft fuselage with 11 bolts. OMS pods are removed during Orbiter Major Modifications. Once removed, the OMS pods undergo in-depth structural inspections, system checks and the thrusters are changed out.

    NASA Image and Video Library

    2003-09-05

    KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, one of two orbital maneuvering system (OMS) pods removed from Endeavour is lowered toward a transporter. The OMS pods are attached to the upper aft fuselage left and right sides. Fabricated primarily of graphite epoxy composite and aluminum, each pod is 21.8 feet long and 11.37 feet wide at its aft end and 8.41 feet wide at its forward end, with a surface area of approximately 435 square feet. Each pod houses the Reaction Control System propulsion components used for inflight maneuvering and is attached to the aft fuselage with 11 bolts. OMS pods are removed during Orbiter Major Modifications. Once removed, the OMS pods undergo in-depth structural inspections, system checks and the thrusters are changed out.

  4. KENNEDY SPACE CENTER, FLA. - Technicians in the Orbiter Processing Facility oversee removal of one of two orbital maneuvering system (OMS) pods from Endeavour. The OMS pods are attached to the upper aft fuselage left and right sides. Fabricated primarily of graphite epoxy composite and aluminum, each pod is 21.8 feet long and 11.37 feet wide at its aft end and 8.41 feet wide at its forward end, with a surface area of approximately 435 square feet. Each pod houses the Reaction Control System propulsion components used for inflight maneuvering and is attached to the aft fuselage with 11 bolts. OMS pods are removed during Orbiter Major Modifications. Once removed, the OMS pods undergo in-depth structural inspections, system checks and the thrusters are changed out.

    NASA Image and Video Library

    2003-09-05

    KENNEDY SPACE CENTER, FLA. - Technicians in the Orbiter Processing Facility oversee removal of one of two orbital maneuvering system (OMS) pods from Endeavour. The OMS pods are attached to the upper aft fuselage left and right sides. Fabricated primarily of graphite epoxy composite and aluminum, each pod is 21.8 feet long and 11.37 feet wide at its aft end and 8.41 feet wide at its forward end, with a surface area of approximately 435 square feet. Each pod houses the Reaction Control System propulsion components used for inflight maneuvering and is attached to the aft fuselage with 11 bolts. OMS pods are removed during Orbiter Major Modifications. Once removed, the OMS pods undergo in-depth structural inspections, system checks and the thrusters are changed out.

  5. KENNEDY SPACE CENTER, FLA. - Workers in the Orbiter Processing Facility prepare to remove one of two orbital maneuvering system (OMS) pods from Endeavour. The OMS pods are attached to the upper aft fuselage left and right sides. Fabricated primarily of graphite epoxy composite and aluminum, each pod is 21.8 feet long and 11.37 feet wide at its aft end and 8.41 feet wide at its forward end, with a surface area of approximately 435 square feet. Each pod houses the Reaction Control System propulsion components used for inflight maneuvering and is attached to the aft fuselage with 11 bolts. OMS pods are removed during Orbiter Major Modifications. Once removed, the OMS pods undergo in-depth structural inspections, system checks and the thrusters are changed out.

    NASA Image and Video Library

    2003-09-05

    KENNEDY SPACE CENTER, FLA. - Workers in the Orbiter Processing Facility prepare to remove one of two orbital maneuvering system (OMS) pods from Endeavour. The OMS pods are attached to the upper aft fuselage left and right sides. Fabricated primarily of graphite epoxy composite and aluminum, each pod is 21.8 feet long and 11.37 feet wide at its aft end and 8.41 feet wide at its forward end, with a surface area of approximately 435 square feet. Each pod houses the Reaction Control System propulsion components used for inflight maneuvering and is attached to the aft fuselage with 11 bolts. OMS pods are removed during Orbiter Major Modifications. Once removed, the OMS pods undergo in-depth structural inspections, system checks and the thrusters are changed out.

  6. KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, one of two orbital maneuvering system (OMS) pods removed from Endeavour is suspended overhead. The OMS pods are attached to the upper aft fuselage left and right sides. Fabricated primarily of graphite epoxy composite and aluminum, each pod is 21.8 feet long and 11.37 feet wide at its aft end and 8.41 feet wide at its forward end, with a surface area of approximately 435 square feet. Each pod houses the Reaction Control System propulsion components used for inflight maneuvering and is attached to the aft fuselage with 11 bolts. OMS pods are removed during Orbiter Major Modifications. Once removed, the OMS pods undergo in-depth structural inspections, system checks and the thrusters are changed out.

    NASA Image and Video Library

    2003-09-05

    KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, one of two orbital maneuvering system (OMS) pods removed from Endeavour is suspended overhead. The OMS pods are attached to the upper aft fuselage left and right sides. Fabricated primarily of graphite epoxy composite and aluminum, each pod is 21.8 feet long and 11.37 feet wide at its aft end and 8.41 feet wide at its forward end, with a surface area of approximately 435 square feet. Each pod houses the Reaction Control System propulsion components used for inflight maneuvering and is attached to the aft fuselage with 11 bolts. OMS pods are removed during Orbiter Major Modifications. Once removed, the OMS pods undergo in-depth structural inspections, system checks and the thrusters are changed out.

  7. KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, one of two orbital maneuvering system (OMS) pods removed from Endeavour is lowered onto a transporter. The OMS pods are attached to the upper aft fuselage left and right sides. Fabricated primarily of graphite epoxy composite and aluminum, each pod is 21.8 feet long and 11.37 feet wide at its aft end and 8.41 feet wide at its forward end, with a surface area of approximately 435 square feet. Each pod houses the Reaction Control System propulsion components used for inflight maneuvering and is attached to the aft fuselage with 11 bolts. OMS pods are removed during Orbiter Major Modifications. Once removed, the OMS pods undergo in-depth structural inspections, system checks and the thrusters are changed out.

    NASA Image and Video Library

    2003-09-05

    KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, one of two orbital maneuvering system (OMS) pods removed from Endeavour is lowered onto a transporter. The OMS pods are attached to the upper aft fuselage left and right sides. Fabricated primarily of graphite epoxy composite and aluminum, each pod is 21.8 feet long and 11.37 feet wide at its aft end and 8.41 feet wide at its forward end, with a surface area of approximately 435 square feet. Each pod houses the Reaction Control System propulsion components used for inflight maneuvering and is attached to the aft fuselage with 11 bolts. OMS pods are removed during Orbiter Major Modifications. Once removed, the OMS pods undergo in-depth structural inspections, system checks and the thrusters are changed out.

  8. Analyzer-based phase-contrast imaging system using a micro focus x-ray source

    NASA Astrophysics Data System (ADS)

    Zhou, Wei; Majidi, Keivan; Brankov, Jovan G.

    2014-08-01

    Here we describe a new in-laboratory analyzer based phase contrast-imaging (ABI) instrument using a conventional X-ray tube source (CXS) aimed at bio-medical imaging applications. Phase contrast-imaging allows visualization of soft tissue details usually obscured in conventional X-ray imaging. The ABI system design and major features are described in detail. The key advantage of the presented system, over the few existing CXS ABI systems, is that it does not require high precision components, i.e., CXS, X-ray detector, and electro-mechanical components. To overcome a main problem introduced by these components, identified as temperature stability, the system components are kept at a constant temperature inside of three enclosures, thus minimizing the electrical and mechanical thermal drifts. This is achieved by using thermoelectric (Peltier) cooling/heating modules that are easy to control precisely. For CXS we utilized a microfocus X-ray source with tungsten (W) anode material. In addition the proposed system eliminates tungsten's multiple spectral lines by selecting monochromator crystal size appropriately therefore eliminating need for the costly mismatched, two-crystal monochromator. The system imaging was fine-tuned for tungsten Kα1 line with the energy of 59.3 keV since it has been shown to be of great clinical significance by a number of researchers at synchrotron facilities. In this way a laboratory system that can be used for evaluating and quantifying tissue properties, initially explored at synchrotron facilities, would be of great interest to a larger research community. To demonstrate the imaging capability of our instrument we use a chicken thigh tissue sample.

  9. Design and fabrication of miniaturized PEM fuel cell combined microreactor with self-regulated hydrogen mechanism

    NASA Astrophysics Data System (ADS)

    Balakrishnan, A.; Frei, M.; Kerzenmacher, S.; Reinecke, H.; Mueller, C.

    2015-12-01

    In this work we present the design and fabrication of the miniaturized PEM fuel cell combined microreactor system with hydrogen regulation mechanism and testing of prototype microreactor. The system consists of two components (i) fuel cell component and (ii) microreactor component. The fuel cell component represents the miniaturized PEM fuel cell system (combination of screen printed fuel cell assembly and an on-board hydrogen storage medium). Hydrogen production based on catalytic hydrolysis of chemical hydride takes place in the microreactor component. The self-regulated hydrogen mechanism based on the gaseous hydrogen produced from the catalytic hydrolysis of sodium borohydride (NaBH4) gets accumulated as bubbles at the vicinity of the hydrophobic coated hydrogen exhaust holes. When the built up hydrogen bubbles pressure exceeds the burst pressure at the hydrogen exhaust holes the bubble collapses. This collapse causes a surge of fresh NaBH4 solution onto the catalyst surface leading to the removal of the reaction by-products formed at the active sites of the catalyst. The catalyst used in the system is platinum deposited on a base substrate. Nickel foam, carbon porous medium (CPM) and ceramic plate were selected as candidates for base substrate for developing a robust catalyst surface. For the first time the platinum layer fabricated by pulsed electrodeposition and dealloying (EPDD) technique is used for hydrolysis of NaBH4. The major advantages of such platinum catalyst layers are its high surface area and their mechanical stability. Prototype microreactor system with self-regulated hydrogen mechanism is demonstrated.

  10. Proposed Role for KaiC-Like ATPases as Major Signal Transduction Hubs in Archaea

    PubMed Central

    2017-01-01

    ABSTRACT All organisms must adapt to ever-changing environmental conditions and accordingly have evolved diverse signal transduction systems. In bacteria, the most abundant networks are built around the two-component signal transduction systems that include histidine kinases and receiver domains. In contrast, eukaryotic signal transduction is dominated by serine/threonine/tyrosine protein kinases. Both of these systems are also found in archaea, but they are not as common and diversified as their bacterial and eukaryotic counterparts, suggesting the possibility that archaea have evolved other, still uncharacterized signal transduction networks. Here we propose a role for KaiC family ATPases, known to be key components of the circadian clock in cyanobacteria, in archaeal signal transduction. The KaiC family is notably expanded in most archaeal genomes, and although most of these ATPases remain poorly characterized, members of the KaiC family have been shown to control archaellum assembly and have been found to be a stable component of the gas vesicle system in Halobacteria. Computational analyses described here suggest that KaiC-like ATPases and their homologues with inactivated ATPase domains are involved in many other archaeal signal transduction pathways and comprise major hubs of complex regulatory networks. We predict numerous input and output domains that are linked to KaiC-like proteins, including putative homologues of eukaryotic DEATH domains that could function as adapters in archaeal signaling networks. We further address the relationships of the archaeal family of KaiC homologues to the bona fide KaiC of cyanobacteria and implications for the existence of a KaiC-based circadian clock apparatus in archaea. PMID:29208747

  11. Environmental Dynamics of Dissolved Black Carbon in the Amazon River

    NASA Astrophysics Data System (ADS)

    Roebuck, J. A., Jr.; Gonsior, M.; Enrich-Prast, A.; Jaffe, R.

    2016-02-01

    Dissolve black carbon (DBC) is an important component in the global carbon cycle and constitutes a significant portion of dissolved organic carbon (DOC) in aquatic systems. While global fluxes of DBC may be well understood, little is known about systematic processing of this carbon pool in fluvial systems. Similar to DOC, DBC composition may change as it moves throughout a river continuum before it is eventually deposited into the ocean. This is especially important for large river systems that are major sources of DOC to the ocean and may have significant impacts on ocean biogeochemistry and carbon cycling. To better understand variations in DBC dynamics throughout a large fluvial system, DBC was quantified using the benzene polycarboxylic acid method (BPCA) in three major tributaries of the Amazon River, each with varying biogeochemical characteristics. Principal component analysis of the BPCA abundances was used to assess the DBC compositional differences between sampling locations. In some rivers, light availability appeared to influence both DBC quantity and quality. Higher concentrations of DBC characterized by a larger, more aromatic DBC pool was found in the Rio Negro, a black water river with high levels of chromophoric dissolved organic matter and low light penetration. In the Rio Tapajós, a clear water river with higher light penetration, lower DBC concentrations characterized by higher abundances of the less polycondensed DBC pool provided evidence of photodecomposition under such conditions. The Rio Madeira, characterized as a white water river with high suspended sediment yields and high mineral/clay content, had the lowest DBC concentrations and the least polycondensed DBC content, suggesting a preferential adsorption of the more highly polycondensed DBC components onto clay particles.

  12. Applicability of a Crack-Detection System for Use in Rotor Disk Spin Test Experiments Being Evaluated

    NASA Technical Reports Server (NTRS)

    Abdul-Aziz, Ali; Baaklini, George Y.; Roth, Don J.

    2004-01-01

    Engine makers and aviation safety government institutions continue to have a strong interest in monitoring the health of rotating components in aircraft engines to improve safety and to lower maintenance costs. To prevent catastrophic failure (burst) of the engine, they use nondestructive evaluation (NDE) and major overhauls for periodic inspections to discover any cracks that might have formed. The lowest cost fluorescent penetrant inspection NDE technique can fail to disclose cracks that are tightly closed during rest or that are below the surface. The NDE eddy current system is more effective at detecting both crack types, but it requires careful setup and operation and only a small portion of the disk can be practically inspected. So that sensor systems can sustain normal function in a severe environment, health-monitoring systems require the sensor system to transmit a signal if a crack detected in the component is above a predetermined length (but below the length that would lead to failure) and lastly to act neutrally upon the overall performance of the engine system and not interfere with engine maintenance operations. Therefore, more reliable diagnostic tools and high-level techniques for detecting damage and monitoring the health of rotating components are very essential in maintaining engine safety and reliability and in assessing life.

  13. A framework for the transition from nursing records to a nursing information system.

    PubMed

    Turley, J P

    1992-01-01

    The future of patient record keeping is being developed now. Critical aspects are in place with the development of computer communication standards for health care. The Institute of Medicine's report on the computerized patient record has galvanized many in the health care field to rethink their methods of record keeping. Nurses need to examine the history of the nursing record and look toward the development of a comprehensive nursing information system. Nurses, along with the other disciplines, must examine what they want the system of the future to encompass. A suggested framework for the information system has four major nursing components: (1) data storage component, (2) transaction log, (3) nursing decision support systems, and (4) an engine to link and combine the first three components and to present a consistent easy-to-use interface to the nurse. Done properly, this approach will reduce the amount of time nurses spend charting, add dimension to their notation, and increase the efficiency of data usage for clinical practice. The nursing information system must allow information availability in a manner that accentuates quality practice while releasing the nurse from time-consuming record keeping. These goals are possible to meet, but only if nurses plan for the design now, before it becomes a fait accompli.

  14. Essential Nutrition and Food Systems Components for School Curricula: Views from Experts in Iran

    PubMed Central

    SADEGHOLVAD, Sanaz; YEATMAN, Heather; OMIDVAR, Nasrin; PARRISH, Anne-Maree; WORSLEY, Anthony

    2017-01-01

    Background: This study aimed to investigate food experts’ views on important nutrition and food systems knowledge issues for education purposes at schools in Iran. Methods: In 2012, semi-structured, face-to-face or telephone interviews were conducted with twenty-eight acknowledged Iranian experts in food and nutrition fields. Participants were selected from four major provinces in Iran (Tehran, Isfahan, Fars and Gilan). Open-ended interview questions were used to identify nutrition and food systems knowledge issues, which experts considered as important to be included in school education programs. Qualitative interviews were analyzed thematically using NVivo. Results: A framework of knowledge that would assist Iranian students and school-leavers to make informed decisions in food-related areas was developed, comprising five major clusters and several sub-clusters. Major knowledge clusters included nutrition basics; food production; every day food-related practices; prevalent nutritional health problems in Iran and improvement of students’ ethical attitudes in the food domain. Conclusion: These findings provide a guide to curriculum developers and policy makers to assess current education curricula in order to optimize students’ knowledge of nutrition and food systems. PMID:28845405

  15. Storytelling and environmental information: connecting schoolchildren and herpetofauna in Morocco.

    PubMed

    Fanini, Lucia; Fahd, Soumia

    2009-06-01

    Northwestern Morocco is undergoing a sudden change in the level of infrastructure growth and pressure on the environment from increased tourism. The ongoing changes are raising questions about how the ecosystem will react, and the relevant drivers of these changes. The Oued Laou valley in north-west Morocco hosts high landscape, species and human cultural diversity. The Talassemtane National Park has been established to preserve the environment in this region; however, what information tools are available to children regarding this environment? The ecosystem is illustrated here using three components: herpetofauna (representing ecosystem components), problems related to water quantity and quality (representing interactions within ecosystem components) and Talassemtane National Park (representing a case of ecosystem management). A children's book was written on this topic, and when the book was delivered to pupils, a questionnaire was included, aimed at determining their sources of environmental information. The results identified major changes in the sources of information utilized by children in this part of Morocco, a clear role of schools in explaining ecosystem components, and an increasing role of TV in environmental information supply. The role of the family was found to be less important than TV or school. Another major source of pupils' environmental knowledge is personal observation and hands-on experience, both for rural and urban children. Children are willing to discover and understand complex systems, and researchers should be encouraged to supply children with correct and up-to-date information on environmental systems, focusing at first on the local environment, as a background for sustainable development. © 2009 ISZS, Blackwell Publishing and IOZ/CAS.

  16. Haematoporphyrin and OO'-diacetylhaematoporphyrin binding by serum and cellular proteins. Implications for the clearance of these photochemotherapeutic agents by cells.

    PubMed Central

    Smith, A; Neuschatz, T

    1983-01-01

    Haematoporphyrin derivative (HpD), a mixture of porphyrins, is currently used as a photochemotherapeutic agent in the treatment of neoplasias. The interaction of purified components of HpD with serum and cellular proteins was investigated using absorption and fluorescence spectroscopy. The interactions of haematoporphyrin and OO'-diacetylhaematoporphyrin with human albumin and with haemopexin, the two major serum porphyrin-binding proteins, show stoichiometries of 1 mol of porphyrin bound per mol of protein. The apparent dissociation constants, Kd, are in the range of 1-2 microM for albumin and 3-4 microM for haemopexin. These two major components of HpD would, after intravenous injection, bind to albumin and circulate in serum as albumin complexes. Free porphyrin rather than porphyrin bound to albumin interacts with Morris hepatoma tissue culture cells. A rapid high-affinity saturable transport system operates at free porphyrin concentrations of less than 2 microM. In addition, fluorescence spectra show that components in rat liver cytosol can bind haematoporphyrin and OO'-diacetylhaematoporphyrin and distinguish these binders from those present in rat serum. PMID:6225429

  17. YUCSA: A CLIPS expert database system to monitor academic performance

    NASA Technical Reports Server (NTRS)

    Toptsis, Anestis A.; Ho, Frankie; Leindekar, Milton; Foon, Debra Low; Carbonaro, Mike

    1991-01-01

    The York University CLIPS Student Administrator (YUCSA), an expert database system implemented in C Language Integrated Processing System (CLIPS), for monitoring the academic performance of undergraduate students at York University, is discussed. The expert system component in the system has already been implemented for two major departments, and it is under testing and enhancement for more departments. Also, more elaborate user interfaces are under development. We describe the design and implementation of the system, problems encountered, and immediate future plans. The system has excellent maintainability and it is very efficient, taking less than one minute to complete an assessment of one student.

  18. Deep Proton Writing for the rapid prototyping of polymer micro-components for optical interconnects and optofluidics

    NASA Astrophysics Data System (ADS)

    Van Erps, Jürgen; Vervaeke, Michael; Ottevaere, Heidi; Hermanne, Alex; Thienpont, Hugo

    2013-07-01

    The use of photonics in data communication and numerous other industrial applications brought plenty of prospects for innovation and opened up different unexplored market opportunities. This is a major driving force for the fabrication of micro-optical and micro-mechanical structures and their accurate alignment and integration into opto-mechanical modules and systems. To this end, we present Deep Proton Writing (DPW) as a powerful rapid prototyping technology for such micro-components. The DPW process consists of bombarding polymer samples (PMMA or SU-8) with swift protons, which results after chemical processing steps in high-quality micro-optical components. One of the strengths of the DPW micro-fabrication technology is the ability to fabricate monolithic building blocks that include micro-optical and mechanical functionalities which can be precisely integrated into more complex photonic systems. In this paper we comment on how we shifted from using 8.3 to 16.5 MeV protons for DPW and give some examples of micro-optical and micro-mechanical components recently fabricated through DPW, targeting applications in optical interconnections and in optofluidics.

  19. Communication architecture for large geostationary platforms

    NASA Technical Reports Server (NTRS)

    Bond, F. E.

    1979-01-01

    Large platforms have been proposed for supporting multipurpose communication payloads to exploit economy of scale, reduce congestion in the geostationary orbit, provide interconnectivity between diverse earth stations, and obtain significant frequency reuse with large multibeam antennas. This paper addresses a specific system design, starting with traffic projections in the next two decades and discussing tradeoffs and design approaches for major components including: antennas, transponders, and switches. Other issues explored are selection of frequency bands, modulation, multiple access, switching methods, and techniques for servicing areas with nonuniform traffic demands. Three-major services are considered: a high-volume trunking system, a direct-to-user system, and a broadcast system for video distribution and similar functions. Estimates of payload weight and d.c. power requirements are presented. Other subjects treated are: considerations of equipment layout for servicing by an orbit transfer vehicle, mechanical stability requirements for the large antennas, and reliability aspects of the large number of transponders employed.

  20. A combination strategy for extraction and isolation of multi-component natural products by systematic two-phase solvent extraction-(13)C nuclear magnetic resonance pattern recognition and following conical counter-current chromatography separation: Podophyllotoxins and flavonoids from Dysosma versipellis (Hance) as examples.

    PubMed

    Yang, Zhi; Wu, Youqian; Wu, Shihua

    2016-01-29

    Despite of substantial developments of extraction and separation techniques, isolation of natural products from natural resources is still a challenging task. In this work, an efficient strategy for extraction and isolation of multi-component natural products has been successfully developed by combination of systematic two-phase liquid-liquid extraction-(13)C NMR pattern recognition and following conical counter-current chromatography separation. A small-scale crude sample was first distributed into 9 systematic hexane-ethyl acetate-methanol-water (HEMWat) two-phase solvent systems for determination of the optimum extraction solvents and partition coefficients of the prominent components. Then, the optimized solvent systems were used in succession to enrich the hydrophilic and lipophilic components from the large-scale crude sample. At last, the enriched components samples were further purified by a new conical counter-current chromatography (CCC). Due to the use of (13)C NMR pattern recognition, the kinds and structures of major components in the solvent extracts could be predicted. Therefore, the method could collect simultaneously the partition coefficients and the structural information of components in the selected two-phase solvents. As an example, a cytotoxic extract of podophyllotoxins and flavonoids from Dysosma versipellis (Hance) was selected. After the systematic HEMWat system solvent extraction and (13)C NMR pattern recognition analyses, the crude extract of D. versipellis was first degreased by the upper phase of HEMWat system (9:1:9:1, v/v), and then distributed in the two phases of the system of HEMWat (2:8:2:8, v/v) to obtain the hydrophilic lower phase extract and lipophilic upper phase extract, respectively. These extracts were further separated by conical CCC with the HEMWat systems (1:9:1:9 and 4:6:4:6, v/v). As results, total 17 cytotoxic compounds were isolated and identified. In general, whole results suggested that the strategy was very efficient for the systematic extraction and isolation of biological active components from the complex biomaterials. Copyright © 2016 Elsevier B.V. All rights reserved.

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