The Impact of Life Events on Job Satisfaction

ERIC Educational Resources Information Center

Georgellis, Yannis; Lange, Thomas; Tabvuma, Vurain

2012-01-01

Employing fixed effects regression techniques on longitudinal data, we investigate how life events affect employees' job satisfaction. Unlike previous work-life research, exploring mostly contemporaneous correlations, we look for evidence of adaptation in the years following major life events. We find evidence of adaptation following the first…

Prevention of the Posttraumatic Fibrotic Response in Joints

DTIC Science & Technology

2015-10-01

surgical procedures and subsequent collection of tissues have been developed and are currently used on a regular basis. Major Task 4: Evaluating the...needed to evaluate the utility of the inhibitory antibody to reduce the flexion contracture of injured knee joints. The employed techniques include...second surgery to remove a pin, and it did not change by the end of the 32nd week 1. Major Task 5: Task 4. Data analysis and statistical evaluation

Digital Forensics Using Local Signal Statistics

ERIC Educational Resources Information Center

Pan, Xunyu

2011-01-01

With the rapid growth of the Internet and the popularity of digital imaging devices, digital imagery has become our major information source. Meanwhile, the development of digital manipulation techniques employed by most image editing software brings new challenges to the credibility of photographic images as the definite records of events. We…

Prince Edward Island Newstarts' Comprehensive Manpower Development System.

ERIC Educational Resources Information Center

Connor, Thomas R.

1971-01-01

An approach to new methods of helping disadvantaged people gain employment taken by Prince Edward Island Newstart is outlined. This approach is a Comprehensive Manpower Development System. The major components of the system consist of: (1) variants of some standard manpower training programs, (2) innovative recruitment and assignment techniques,…

Least squares polynomial chaos expansion: A review of sampling strategies

NASA Astrophysics Data System (ADS)

Hadigol, Mohammad; Doostan, Alireza

2018-04-01

As non-institutive polynomial chaos expansion (PCE) techniques have gained growing popularity among researchers, we here provide a comprehensive review of major sampling strategies for the least squares based PCE. Traditional sampling methods, such as Monte Carlo, Latin hypercube, quasi-Monte Carlo, optimal design of experiments (ODE), Gaussian quadratures, as well as more recent techniques, such as coherence-optimal and randomized quadratures are discussed. We also propose a hybrid sampling method, dubbed alphabetic-coherence-optimal, that employs the so-called alphabetic optimality criteria used in the context of ODE in conjunction with coherence-optimal samples. A comparison between the empirical performance of the selected sampling methods applied to three numerical examples, including high-order PCE's, high-dimensional problems, and low oversampling ratios, is presented to provide a road map for practitioners seeking the most suitable sampling technique for a problem at hand. We observed that the alphabetic-coherence-optimal technique outperforms other sampling methods, specially when high-order ODE are employed and/or the oversampling ratio is low.

Reducing software mass through behavior control. [of planetary roving robots

NASA Technical Reports Server (NTRS)

Miller, David P.

1992-01-01

Attention is given to the tradeoff between communication and computation as regards a planetary rover (both these subsystems are very power-intensive, and both can be the major driver of the rover's power subsystem, and therefore the minimum mass and size of the rover). Software techniques that can be used to reduce the requirements on both communciation and computation, allowing the overall robot mass to be greatly reduced, are discussed. Novel approaches to autonomous control, called behavior control, employ an entirely different approach, and for many tasks will yield a similar or superior level of autonomy to traditional control techniques, while greatly reducing the computational demand. Traditional systems have several expensive processes that operate serially, while behavior techniques employ robot capabilities that run in parallel. Traditional systems make extensive world models, while behavior control systems use minimal world models or none at all.

Employment for adults with autism spectrum disorders: A retrospective review of a customized employment approach.

PubMed

Wehman, Paul; Brooke, Valerie; Brooke, Alissa Molinelli; Ham, Whitney; Schall, Carol; McDonough, Jennifer; Lau, Stephanie; Seward, Hannah; Avellone, Lauren

2016-01-01

Over the past few decades, there has been an increase in prevalence of children with autism spectrum disorders (ASD), and those children are now becoming young adults in need of competitive integrated employment (CIE). Customized employment (CE) is one pathway to employment that has been successful for other individuals with developmental disabilities (DD), though research has been very limited on the effectiveness with individuals with ASD. This paper provides a retrospective review of 64 individuals with ASD who came to our program from 2009 to 2014 for supported employment services as referred by the state vocational rehabilitation services agency. Employment specialists engaged in situational assessment, discovery, job development, customized job descriptions, on-site training and support, positive behavioral supports, and job retention techniques. The employment specialists were responsible for tracking their actual time spent working directly with or for the jobseeker with autism spectrum disorders (ASD). All vocational rehabilitation clients with ASD served during this time successfully secured CIE, and maintained their employment with ongoing supports, with intensity of support time decreasing over time. The majority (63/64, 98.4%) of individuals successfully secured CIE through the use of supported employment, in 72 unique employment positions. Of the majority of the individuals who secured employment, 77% (50) individuals indicated that they had never worked before and additional 18% (12) reported having short intermittent histories of employment. Despite this lack of employment experience, in all cases the jobseeker directed the job search and ultimately the job selection. Copyright © 2016 Elsevier Ltd. All rights reserved.

Multielemental analyses of isomorphous Indian garnet gemstones by XRD and external pixe techniques.

PubMed

Venkateswarulu, P; Srinivasa Rao, K; Kasipathi, C; Ramakrishna, Y

2012-12-01

Garnet gemstones were collected from parts of Eastern Ghats geological formations of Andhra Pradesh, India and their gemological studies were carried out. Their study of chemistry is not possible as they represent mixtures of isomorphism nature, and none of the individual specimens indicate independent chemistry. Hence, non-destructive instrumental methodology of external PIXE technique was employed to understand their chemistry and identity. A 3 MeV proton beam was employed to excite the samples. In the present study geochemical characteristics of garnet gemstones were studied by proton induced X-ray emission. Almandine variety of garnet is found to be abundant in the present study by means of their chemical contents. The crystal structure and the lattice parameters were estimated using X-Ray Diffraction studies. The trace and minor elements are estimated using PIXE technique and major compositional elements are confirmed by XRD studies. The technique is found very useful in characterizing the garnet gemstones. The present work, thus establishes usefulness and versatility of the PIXE technique with external beam for research in Geo-scientific methodology. Copyright © 2012 Elsevier Ltd. All rights reserved.

The AXAF technology program: The optical flats tests

NASA Technical Reports Server (NTRS)

Williams, A. C.; Harper, J. D.; Reily, J. C.; Weisskopf, M. C.; Wyman, C. L.; Zombeck, M.

1984-01-01

The results of a technology program aimed at determining the limits of surface polishing for reflecting X-ray telescopes is presented. This program is part of the major task of developing the Advanced X-ray Astrophysical Facility (AXAF). By studying the optical properties of state-of-the-art polished flat surfaces, conclusions were drawn as to the potential capability of AXAF. Surface microtopography of the flats as well as their figure are studied by X-ray, visual, and mechanical techniques. These techniques and their results are described. The employed polishing techniques are more than adequate for the specifications of the AXAF mirrors.

Factors Influencing International Students' Choice of an Education Destination--A Correspondence Analysis

ERIC Educational Resources Information Center

Shanka, Tekle; Quintal, Vanessa; Taylor, Ruth

2005-01-01

A correspondence analysis technique was employed to elicit information from international students pertaining to their choice of study destination. A survey of international students at a major Australian university revealed that the proximity of the city to the students' home countries, in addition to safety, the educational quality/variety, etc.…

A Review of Statistical Disclosure Control Techniques Employed by Web-Based Data Query Systems.

PubMed

Matthews, Gregory J; Harel, Ofer; Aseltine, Robert H

We systematically reviewed the statistical disclosure control techniques employed for releasing aggregate data in Web-based data query systems listed in the National Association for Public Health Statistics and Information Systems (NAPHSIS). Each Web-based data query system was examined to see whether (1) it employed any type of cell suppression, (2) it used secondary cell suppression, and (3) suppressed cell counts could be calculated. No more than 30 minutes was spent on each system. Of the 35 systems reviewed, no suppression was observed in more than half (n = 18); observed counts below the threshold were observed in 2 sites; and suppressed values were recoverable in 9 sites. Six sites effectively suppressed small counts. This inquiry has revealed substantial weaknesses in the protective measures used in data query systems containing sensitive public health data. Many systems utilized no disclosure control whatsoever, and the vast majority of those that did deployed it inconsistently or inadequately.

Detrended fluctuation analysis for major depressive disorder.

PubMed

Mumtaz, Wajid; Malik, Aamir Saeed; Ali, Syed Saad Azhar; Yasin, Mohd Azhar Mohd; Amin, Hafeezullah

2015-01-01

Clinical utility of Electroencephalography (EEG) based diagnostic studies is less clear for major depressive disorder (MDD). In this paper, a novel machine learning (ML) scheme was presented to discriminate the MDD patients and healthy controls. The proposed method inherently involved feature extraction, selection, classification and validation. The EEG data acquisition involved eyes closed (EC) and eyes open (EO) conditions. At feature extraction stage, the de-trended fluctuation analysis (DFA) was performed, based on the EEG data, to achieve scaling exponents. The DFA was performed to analyzes the presence or absence of long-range temporal correlations (LRTC) in the recorded EEG data. The scaling exponents were used as input features to our proposed system. At feature selection stage, 3 different techniques were used for comparison purposes. Logistic regression (LR) classifier was employed. The method was validated by a 10-fold cross-validation. As results, we have observed that the effect of 3 different reference montages on the computed features. The proposed method employed 3 different types of feature selection techniques for comparison purposes as well. The results show that the DFA analysis performed better in LE data compared with the IR and AR data. In addition, during Wilcoxon ranking, the AR performed better than LE and IR. Based on the results, it was concluded that the DFA provided useful information to discriminate the MDD patients and with further validation can be employed in clinics for diagnosis of MDD.

The Role of Speaker Identification in Korean University Students' Attitudes towards Five Varieties of English

ERIC Educational Resources Information Center

Yook, Cheongmin; Lindemann, Stephanie

2013-01-01

This study investigates how the attitudes of 60 Korean university students towards five varieties of English are affected by the identification of the speaker's nationality and ethnicity. The study employed both a verbal guise technique and questions eliciting overt beliefs and preferences related to learning English. While the majority of the…

Identifying Core Competencies to Advance Female Professors' Careers: An Exploratory Study in United States Academia

ERIC Educational Resources Information Center

Seo, Ga-eun; Hedayati Mehdiabadi, Amir; Huang, Wenhao

2017-01-01

This exploratory study aims to identify the core competencies necessary to successfully advance the careers of female associate professors in higher education. To ascertain these core career competencies, a critical incident interview technique was employed. One-to-one semi-structured interviews with six female full professors at a major research…

Advanced Regenerative Environmental Control and Life Support Systems: Air and Water Regeneration

NASA Technical Reports Server (NTRS)

Schubert, F. H.; Wynveen, R. A.; Quattrone, P. D.

1985-01-01

Extended manned space missions will require regenerative life support techniques. Past manned missions used nonregenerative expendables, except for a molecular sieve based carbon dioxide removal system aboard Skylab. The resupply penalties associated with expendables becomes prohibitive as crew size and mission duration increase. The Space Station scheduled to be operational in the 1990's is based on a crew of four to sixteen and a resupply period of 90 days or greater. It will be the first major spacecraft to employ regenerable techniques for life support. The techniques to be used in the requirements for the space station are addressed.

Advanced regenerative environmental control and life support systems - Air and water regeneration

NASA Technical Reports Server (NTRS)

Schubert, F. H.; Wynveen, R. A.; Quattrone, P. D.

1984-01-01

Extended manned space missions will require regenerative life support techniques. Past U.S. manned missions used nonregenerative expendables, except for a molecular sieve-based carbon dioxide removal system aboard Skylab. The resupply penalties associated with expandables becomes prohibitive as crew size and mission duration increase. The U.S. Space Station, scheduled to be operational in the 1990's, is based on a crew of four to sixteen and a resupply period of 90 days or greater. It will be the first major spacecraft to employ regenerable techniques for life support. The paper uses the requirements for the Space Station to address these techniques.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keepin, G.R.

Over the years the Los Alamos safeguards program has developed, tested, and implemented a broad range of passive and active nondestructive analysis (NDA) instruments (based on gamma and x-ray detection and neutron counting) that are now widely employed in safeguarding nuclear materials of all forms. Here very briefly, the major categories of gamma ray and neutron based NDA techniques, give some representative examples of NDA instruments currently in use, and cite a few notable instances of state-of-the-art NDA technique development. Historical aspects and a broad overview of the safeguards program are also presented.

The Challenges and Advances in Diagnosis of Vector-Borne Diseases: Where Do We Stand?

PubMed

Kuleš, Josipa; Potocnakova, Lenka; Bhide, Katarina; Tomassone, Laura; Fuehrer, Hans-Peter; Horvatić, Anita; Galan, Asier; Guillemin, Nicolas; Nižić, Petra; Mrljak, Vladimir; Bhide, Mangesh

2017-05-01

Vector-borne diseases (VBD) are of major importance to human and animal health. In recent years, VBD have been emerging or re-emerging in many geographical areas, alarming new disease threats and economic losses. The precise diagnosis of many of these diseases still remains a major challenge because of the lack of comprehensive data available on accurate and reliable diagnostic methods. Here, we conducted a systematic and in-depth review of the former, current, and upcoming techniques employed for the diagnosis of VBD.

Examining Differences in Mathematics and Reading Achievement among Grade 5 Pupils in Vietnam

ERIC Educational Resources Information Center

Hungi, Njora

2008-01-01

This study employed a multilevel technique to examine pupil-, school- and province-level factors that influence achievement in mathematics and reading of Grade 5 primary school pupils in Vietnam. The data for this study were collected as part of a major survey that sought to examine the quality of education offered in Vietnam primary schools.…

Working with Organizations to Develop "New Careers" Programs. Technical Monograph No. 10, Publication No. 110.

ERIC Educational Resources Information Center

Pruger, Robert; Specht, Harry

This report on a job creation program for poor people deals with the organizations within which jobs were created, the responses of the organizations to the jobs, and the techniques which seemed useful in working with the organizations. Major sections include: (1) Employment, Unemployment and New Careers, (2) Organizational Barriers, (3) The Forms…

Scanning angle Raman spectroscopy: Investigation of Raman scatter enhancement techniques for chemical analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meyer, Matthew W.

2013-01-01

This thesis outlines advancements in Raman scatter enhancement techniques by applying evanescent fields, standing-waves (waveguides) and surface enhancements to increase the generated mean square electric field, which is directly related to the intensity of Raman scattering. These techniques are accomplished by employing scanning angle Raman spectroscopy and surface enhanced Raman spectroscopy. A 1064 nm multichannel Raman spectrometer is discussed for chemical analysis of lignin. Extending dispersive multichannel Raman spectroscopy to 1064 nm reduces the fluorescence interference that can mask the weaker Raman scattering. Overall, these techniques help address the major obstacles in Raman spectroscopy for chemical analysis, which include themore » inherently weak Raman cross section and susceptibility to fluorescence interference.« less

Therapeutic interventions employed by Greater Toronto Area chiropractors on pregnant patients: results of a cross-sectional online survey

PubMed Central

Yuen, Tammy; Wells, Kayla; Benoit, Samantha; Yohanathan, Sahila; Capelletti, Lauren; Stuber, Kent

2013-01-01

Introduction: Due to different biomechanical, nutritional, and hormonal considerations, it is possible that chiropractors may employ different therapeutic interventions and recommendations for pregnant patients than non-pregnant ones. The objective of this study was to determine the therapeutic interventions that chiropractors who are members of the Ontario Chiropractic Association in the Greater Toronto Area most commonly provide to pregnant patients. Methods: An introductory e-mail was sent in October 2011 to 755 members of the Ontario Chiropractic Association within the Greater Toronto Area five days prior to a 15 question survey being distributed via e-mail. Reminder e-mails were sent 13 days and 27 days later. Using descriptive statistics, demographic information was reported along with reported use of different treatments and recommendations for pregnant patients Results: A response rate of 23% was obtained. The majority of the respondents (90%) reported using the Diversified technique on pregnant patients, followed by soft tissue therapy (62%) and Activator (42%). The most common adjunctive therapy recommended to pregnant patients was referral to massage therapy (90%). Most of the respondents (92%) indicated that they prescribe stretching exercises to pregnant patients and recommend a multivitamin (84%) or folic acid (81%) to pregnant patients. Conclusion: In agreement with previous research on chiropractic technique usage on non-pregnant patients, the majority of respondents indicated treating pregnant patients with the Diversified technique, with other chiropractic techniques being utilized at varying rates on pregnant patients. Most respondents indicated prescribing exercise, and making adjunctive and nutritional recommendations frequently for their pregnant patients. PMID:23754858

Process for measuring degradation of sulfur hexafluoride in high voltage systems

DOEpatents

Sauers, Isidor

1986-01-01

This invention is a method of detecting the presence of toxic and corrosive by-products in high voltage systems produced by electrically induced degradation of SF.sub.6 insulating gas in the presence of certain impurities. It is an improvement over previous methods because it is extremely sensitive, detecting by-products present in parts per billion concentrations, and because the device employed is of a simple design and takes advantage of the by-products natural affinity for fluoride ions. The method employs an ion-molecule reaction cell in which negative ions of the by-products are produced by fluorine attachment. These ions are admitted to a negative ion mass spectrometer and identified by their spectra. This spectrometry technique is an improvement over conventional techniques because the negative ion peaks are strong and not obscured by a major ion spectra of the SF.sub.6 component as is the case in positive ion mass spectrometry.

Process for measuring degradation of sulfur hexafluoride in high voltage systems

DOEpatents

Sauers, I.

1985-04-23

This invention is a method of detecting the presence of toxic and corrosive by-products in high voltage systems produced by electrically induced degradation of SF/sub 6/ insulating gas in the presence of certain impurities. It is an improvement over previous methods because it is extremely sensitive, detecting by-products present in parts per billion concentrations, and because the device employed is of a simple design and takes advantage of the by-products natural affinity for fluoride ions. The method employs an ion-molecule reaction cell in which negative ions of the by-products are produced by fluorine attachment. These ions are admitted to a negative ion mass spectrometer and identified by their spectra. This spectrometry technique is an improvement over conventional techniques because the negative ion peaks are strong and not obscured by a major ion spectra of the SF/sub 6/ component as is the case in positive ion mass spectrometry.

Application of cell and biomaterial-based tissue engineering methods in the treatment of cartilage, menisci and ligament injuries.

PubMed

Trzeciak, Tomasz; Richter, Magdalena; Suchorska, Wiktoria; Augustyniak, Ewelina; Lach, Michał; Kaczmarek, Małgorzata; Kaczmarczyk, Jacek

2016-03-01

Over 20 years ago it was realized that the traditional methods of the treatment of injuries to joint components: cartilage, menisci and ligaments, did not give satisfactory results and so there is a need of employing novel, more effective therapeutic techniques. Recent advances in molecular biology, biotechnology and polymer science have led to both the experimental and clinical application of various cell types, adapting their culture conditions in order to ensure a directed differentiation of the cells into a desired cell type, and employing non-toxic and non-immunogenic biomaterial in the treatment of knee joint injuries. In the present review the current state of knowledge regarding novel cell sources, in vitro conditions of cell culture and major important biomaterials, both natural and synthetic, used in cartilage, meniscus and ligament repair by tissue engineering techniques are described, and the assets and drawbacks of their clinical application are critically evaluated.

Survey of attitudes, materials and methods employed in endodontic treatment by general dental practitioners in North Jordan.

PubMed

Al-Omari, Wael M

2004-09-10

BACKGROUND: General dental practitioners provide the majority of endodontic treatment in Jordan. The aim of this study was to gather information on the methods, materials and attitudes employed in root canal treatment by dentists in North Jordan, in order to evaluate and improve the quality of current practice. METHODS: A questionnaire was posted to all registered general dental practitioners working in private practice in Irbid Governate in North Jordan (n = 181). The questionnaire included information on methods, materials and techniques used in endodontic treatment. RESULTS: Reply rate was 72% (n = 131). The results demonstrated that only five dentists used rubber dam occasionally and not routinely. The majority used cotton rolls for isolation solely or in combination with a high volume saliva ejector (n = 116). The most widely used irrigants were sodium hypochlorite and hydrogen peroxide, which were used by 32.9% (n = 43) and 33.6% (n = 44) of the respondents, respectively. Forty eight percent of the respondents (n = 61) used the cold lateral condensation technique for canal obturation, 31.3% (n = 41) used single cone, 9.9% (n = 13) used vertical condensation and 12.2% (n = 16) used paste or cement only for the obturation. The majority used zinc oxide eugenol as a sealer (72.5%). All, but one, respondents used hand instruments for canal preparation and the technique of choice was step back (52.7%). More than 50% (n = 70) of the dentists took one radiograph for determining the working length, whilst 22.9% (n = 30) did not take any radiograph at all. Most practitioners performed treatment in three visits for teeth with two or more root canals, and in two visits for teeth with a single root canal. CONCLUSIONS: This study indicates that dentists practicing in North Jordan do not comply with international quality standards and do not use recently introduced techniques. Many clinicians never take a radiograph for determining the working length and never used rubber dam or intra-canal medicaments.

Thermoelectrically cooled water trap

DOEpatents

Micheels, Ronald H [Concord, MA

2006-02-21

A water trap system based on a thermoelectric cooling device is employed to remove a major fraction of the water from air samples, prior to analysis of these samples for chemical composition, by a variety of analytical techniques where water vapor interferes with the measurement process. These analytical techniques include infrared spectroscopy, mass spectrometry, ion mobility spectrometry and gas chromatography. The thermoelectric system for trapping water present in air samples can substantially improve detection sensitivity in these analytical techniques when it is necessary to measure trace analytes with concentrations in the ppm (parts per million) or ppb (parts per billion) partial pressure range. The thermoelectric trap design is compact and amenable to use in a portable gas monitoring instrumentation.

Operational Evaluation of Self-Paced Instruction in U.S. Army Training.

DTIC Science & Technology

1979-01-01

one iteration of each course, and the on -going refinement and adjustment of managerial techniques. Research Approach A quasi - experimental approach was...research design employed experimental and control groups , posttest only with non-random groups . The design dealt with the six major areas identified as...course on Interpersonal Communications were conducted in the conventional, group -paced manner. Experimental course materials. Wherever possible, existing

Riparian habitat on the Humboldt River, Deeth to Elko, Nevada

NASA Technical Reports Server (NTRS)

Price, K. P.; Ridd, M. K.

1983-01-01

A map inventory of the major habitat types existing along the Humbolt River riparian zone in Nevada is described. Through aerialphotography, 16 riparian habitats are mapped that describe the ecological relationships between soil and vegetation types, flooding and soil erosion, and the various management practices employed to date. The specific land and water management techniques and their impact on the environment are considered.

Feedforward interview technique in obstetrics and gynaecology residents: a fact or fallacy.

PubMed

Sami, Shehla; Ahmad, Amina

2015-01-01

To determine the role of Feedforward Interview (FFI) technique in motivating residents of Obstetrics and Gynaecology for better learning and performance. An explorative study with mixed method approach being employed. Department of Obstetrics and Gynaecology, Sandeman (Provincial) Hospital, Quetta, from November 2010 till May 2013. Feedforward interview technique was complimented by survey questionnaire employing similar philosophy of FFI to triangulate data through two methods. Survey questionnaire was filled-up by 21 residents and analysed by SPSS version 17. Fourteen of these participants were identified for in-depth Feedforward Interviews (FFI), based on nonprobability purposive sampling after informed consent, and content analysis was done. Feedforward interview technique enabled majority of residents in recalling minimum of 3 positive experiences, mainly related to surgical experiences, which enhanced their motivation to aspire for further improvement in this area. Hard work was the main personal contributing factor both in FFI and survey. In addition to identifying clinical experiences enhancing desire to learn, residents also reported need for more academic support as an important factor which could also boost motivation to attain better performance. Feedforward interview technique not only helps residents in recalling positive learning experiences during their training but it also has a significant influence on developing insight about one's performance and motivating residents to achieve higher academic goals.

American wild celery (Vallisneria americana): Ecological considerations for restoration

USGS Publications Warehouse

Korschgen, C.E.; Green, W.L.

1988-01-01

The success of vegetation management programs for waterfowl is dependent on knowing the physical and physiological requirements of target species. Lakes and riverine impoundments that contain an abundance of the American wildcelery (Vallisneria americana ) have traditionally been favored by canvasbacks (Aythya valisineria ) and other waterfowl as feeding areas during migration. Information on the ecology of American wildcelery is summarized to serve as a guide for potential wetland restoration projects. Techniques are described for transplanting winter buds. Management programs that employ these techniques should define objectives clearly and evaluate the water regime carefully before initiating major restoration.

Effects of surface polishing on the microstrain behavior of telescope mirror materials

NASA Technical Reports Server (NTRS)

Eul, W. A.; Woods, W. W.

1973-01-01

Rough ground silicic mirror substrate materials were found in previous investigations to exhibit significant surface yield. This effect was removed by surface etching, a procedure not normally employed in the finishing of optical telescope mirrors. The effects of fine grinding and polishing techniques as well as graded etching are investigated. Torsional shear measurements of yield strain versus stress are made on four candidate mirror substrate materials: polycrystalline silicon, ULE silica 7971, CER-VIT 101, and fused silica 7940. Commonly employed fine grinding and polishing practices are shown to remove a major portion of the surface yield found in rough ground mirror substrate materials.

Goal Setting and Treatment Adherence among Patients with Chronic Illness and Depressive Symptoms: Applying a Patient-Centered Approach

PubMed Central

Houston, Eric; Tatum, Alexander K.; Guy, Arryn; Mikrut, Cassandra; Yoder, Wren

2016-01-01

Objective: Poor treatment adherence is a major problem among individuals with chronic illness. Research indicates that adherence is worsened when accompanied by depressive symptoms. In this preliminary study, we aimed to describe how a patient-centered approach could be employed to aid patients with depressive symptoms in following their treatment regimens. Methods: The sample consisted of 14 patients undergoing antiretroviral therapy (ART) for HIV who reported clinically-significant depressive symptoms. Participant ratings of 23 treatment-related statements were examined using two assessment and analytic techniques. Interviews were conducted with participants to determine their views of information based on the technique. Results: Results indicate that while participants with optimal adherence focused on views of treatment associated with side effects to a greater extent than participants with poor adherence, they tended to relate these side effects to sources of intrinsic motivation. Conclusion: The study provides examples of how practitioners could employ the assessment techniques outlined to better understand how patients think about treatment and aid them in effectively framing their health-related goals. PMID:26755463

Goal Setting and Treatment Adherence Among Patients With Chronic Illness and Depressive Symptoms: Applying a Patient-Centered Approach.

PubMed

Houston, Eric; Tatum, Alexander K; Guy, Arryn; Mikrut, Cassandra; Yoder, Wren

2015-10-26

Poor treatment adherence is a major problem among individuals with chronic illness. Research indicates that adherence is worsened when accompanied by depressive symptoms. In this preliminary study, we aimed to describe how a patient-centered approach could be employed to aid patients with depressive symptoms in following their treatment regimens. The sample consisted of 14 patients undergoing antiretroviral therapy (ART) for HIV who reported clinically-significant depressive symptoms. Participant ratings of 23 treatment-related statements were examined using two assessment and analytic techniques. Interviews were conducted with participants to determine their views of information based on the technique. Results indicate that while participants with optimal adherence focused on views of treatment associated with side effects to a greater extent than participants with poor adherence, they tended to relate these side effects to sources of intrinsic motivation. The study provides examples of how practitioners could employ the assessment techniques outlined to better understand how patients think about treatment and aid them in effectively framing their health-related goals.

Audit of the annual reports of directors of public health: production methods.

PubMed

Sidhu, K S

1992-07-01

An audit of production methods used for the Directors of Public Health (DsPH) Annual Report of the health of their local population. Postal questionnaire survey. 23 Departments of Public Health in the West Midlands Region. Costs and problems relating to different production techniques used. The majority of DsPH favoured reports with figures and graphs. This led to most DsPH using in-house desktop publishing or employing external graphic designers. Those using the former technique had more problems related to computers and felt they spent too much medical time working on the document. However, they also valued the relative low cost, editorial freedom and the ability to correct mistakes easily. Departments which employed external graphic designers generally paid more, but appreciated the extra time made available by delegating the work. They also felt that the expertise was valuable in document design. However, inaccuracies were cited as being more difficult to correct. Perhaps the best way of producing an annual report is to amalgamate the two commonest production techniques (i.e. external graphic design and in-house desktop publishing).

Optimum projection pattern generation for grey-level coded structured light illumination systems

NASA Astrophysics Data System (ADS)

Porras-Aguilar, Rosario; Falaggis, Konstantinos; Ramos-Garcia, Ruben

2017-04-01

Structured light illumination (SLI) systems are well-established optical inspection techniques for noncontact 3D surface measurements. A common technique is multi-frequency sinusoidal SLI that obtains the phase map at various fringe periods in order to estimate the absolute phase, and hence, the 3D surface information. Nevertheless, multi-frequency SLI systems employ multiple measurement planes (e.g. four phase shifted frames) to obtain the phase at a given fringe period. It is therefore an age old challenge to obtain the absolute surface information using fewer measurement frames. Grey level (GL) coding techniques have been developed as an attempt to reduce the number of planes needed, because a spatio-temporal GL sequence employing p discrete grey-levels and m frames has the potential to unwrap up to pm fringes. Nevertheless, one major disadvantage of GL based SLI techniques is that there are often errors near the border of each stripe, because an ideal stepwise intensity change cannot be measured. If the step-change in intensity is a single discrete grey-level unit, this problem can usually be overcome by applying an appropriate threshold. However, severe errors occur if the intensity change at the border of the stripe exceeds several discrete grey-level units. In this work, an optimum GL based technique is presented that generates a series of projection patterns with a minimal gradient in the intensity. It is shown that when using this technique, the errors near the border of the stripes can be significantly reduced. This improvement is achieved with the choice generated patterns, and does not involve additional hardware or special post-processing techniques. The performance of that method is validated using both simulations and experiments. The reported technique is generic, works with an arbitrary number of frames, and can employ an arbitrary number of grey-levels.

Spectrometric microbiological analyzer

NASA Astrophysics Data System (ADS)

Schlager, Kenneth J.; Meissner, Ken E.

1996-04-01

Currently, there are four general approaches to microbiological analysis, i.e., the detection, identification and quantification of micro-organisms: (1) Traditional culturing and staining procedures, metabolic fermentations and visual morphological characteristics; (2) Immunological approaches employing microbe-specific antibodies; (3) Biotechnical techniques employing DNA probes and related genetic engineering methods; and (4) Physical measurement techniques based on the biophysical properties of micro-organisms. This paper describes an instrumentation development in the fourth of the above categories, physical measurement, that uses a combination of fluorometric and light scatter spectra to detect and identify micro-organisms at the species level. A major advantage of this approach is the rapid turnaround possible in medical diagnostic or water testing applications. Fluorometric spectra serve to define the biochemical characteristics of the microbe, and light scatter spectra the size and shape morphology. Together, the two spectra define a 'fingerprint' for each species of microbe for detection, identification and quantification purposes. A prototype instrument has been developed and tested under NASA sponsorship based on fluorometric spectra alone. This instrument demonstrated identification and quantification capabilities at the species level. The paper reports on test results using this instrument, and the benefits of employing a combination of fluorometric and light scatter spectra.

A methodology for automated CPA extraction using liver biopsy image analysis and machine learning techniques.

PubMed

Tsipouras, Markos G; Giannakeas, Nikolaos; Tzallas, Alexandros T; Tsianou, Zoe E; Manousou, Pinelopi; Hall, Andrew; Tsoulos, Ioannis; Tsianos, Epameinondas

2017-03-01

Collagen proportional area (CPA) extraction in liver biopsy images provides the degree of fibrosis expansion in liver tissue, which is the most characteristic histological alteration in hepatitis C virus (HCV). Assessment of the fibrotic tissue is currently based on semiquantitative staging scores such as Ishak and Metavir. Since its introduction as a fibrotic tissue assessment technique, CPA calculation based on image analysis techniques has proven to be more accurate than semiquantitative scores. However, CPA has yet to reach everyday clinical practice, since the lack of standardized and robust methods for computerized image analysis for CPA assessment have proven to be a major limitation. The current work introduces a three-stage fully automated methodology for CPA extraction based on machine learning techniques. Specifically, clustering algorithms have been employed for background-tissue separation, as well as for fibrosis detection in liver tissue regions, in the first and the third stage of the methodology, respectively. Due to the existence of several types of tissue regions in the image (such as blood clots, muscle tissue, structural collagen, etc.), classification algorithms have been employed to identify liver tissue regions and exclude all other non-liver tissue regions from CPA computation. For the evaluation of the methodology, 79 liver biopsy images have been employed, obtaining 1.31% mean absolute CPA error, with 0.923 concordance correlation coefficient. The proposed methodology is designed to (i) avoid manual threshold-based and region selection processes, widely used in similar approaches presented in the literature, and (ii) minimize CPA calculation time. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

A scoping review of qualitative research in peer-reviewed dental publications.

PubMed

Gussy, M; Dickson-Swift, V; Adams, J

2013-08-01

Qualitative research designs are being used increasingly in dental research. This paper describes the extent and range of dental research in which qualitative methods have been employed as well as the techniques of data collection and analysis preferred by dental researchers. A scoping review was conducted to locate studies published in dental journals, which reported the use of qualitative methods. Data concerning the focus of the research and the reported qualitative techniques were extracted. Studies included in the review totalled 197. The majority of qualitative research captured in this scoping study focussed on three main areas: dental education, professional dental and dental educators' activities and experiences and the patient/public perceptions. Interviews and focus group discussions were the most commonly selected techniques for data collection. The majority of the studies included in the scoping review had a focus on education of dental professionals the activities of dental professionals or the reported perceptions of or experiences with dental services by patients or members of the public. Little research was located, which explored peoples' personal experience of dental conditions. Research reported in dental publications has a heavy bias towards the use of focus groups and interview data collection techniques. © 2012 John Wiley & Sons A/S.

Elemental X-ray mapping of agglutinated foraminifer tests: A non- destructive technique for determining compositional characteristics.

USGS Publications Warehouse

Commeau, R.F.; Reynolds, Leslie A.; Poag, C.W.

1985-01-01

The composition of agglutinated foraminiferal tests vary remarkably in response to local substrate characteristics, physiochemical properties of the water column and species- dependant selectivity of test components. We have employed a technique that combines a scanning electron microscope with an energy dispersive X-ray spectrometer system to identify major and minor elemental constituents of agglutinated foraminiferal walls. As a sample is bombarded with a beam of high energy electrons, X-rays are generated that are characteristic of the elements present. As a result, X- ray density maps can be produced for each of several elements present in the tests of agglutinated foraminifers. 

Conservative management of a spleen trauma using radiofrequency.

PubMed

Stella, Mattia; Percivale, Andrea; Pasqualini, Massimo; Pittaluga, Michele; Gandolfo, Nicola; Pellicci, Riccardo

2005-01-01

Conservative operative management of a splenic injury has become more and more employed in order to preserve the immune function of the organ. A case of a rupture of the spleen successfully treated with the use of a radiofrequency thermal energy generator is eported. The parenchymal tear was coagulated by a one cooled tip needle electrode. There were no postoperative complications and the function of the spleen was preserved. The technique cannot be applied in case of lesion of the major vessels or in case of avulsion of the hilum. This technique integrates to the others to make the operative conservative management of a splenic injury more and more feasible.

Community participation in health activities in an Amazon community of Brazil.

PubMed

Tauil, M C; de Azevedo, A C

1978-01-01

This article describes community participation in a comprehensive eight-year health program at Porto Nacional, a town in Brazils Amazon region. The authors discuss various techniques employed to encourage community participation, indicate methods used to resolve low-key conflicts in a positive manner, describe the major contributions made by community participation in this program, and present a number of conclusions considered applicable to other communities in this part of Brazil.

Study of High Temperature Failure Mechanisms in Ceramics

DTIC Science & Technology

1988-06-01

The major experimental 4 techniques employed in the program are the use of small- angle neutron scattering to characterize cavity nucleation and growth...creep crackgrowth. Of particular interest are the development of a stochastic model of grainboundary sliding and a micromechanical model that relates...Accession For NTIS GF.A&I DTIC T,’ IDi st ribut Ion’ ;i Avillii~diii l l= (~~ I. RESEARCH OBJECTIVES I. Utilize small- angle neutron scattering to

AI in manufacturing

NASA Astrophysics Data System (ADS)

Gross, John E.; Minato, Rick; Smith, David M.; Loftin, R. B.; Savely, Robert T.

1991-10-01

AI techniques are shown to have been useful in such aerospace industry tasks as vehicle configuration layouts, process planning, tool design, numerically-controlled programming of tools, production scheduling, and equipment testing and diagnosis. Accounts are given of illustrative experiences at the production facilities of three major aerospace defense contractors. Also discussed is NASA's autonomous Intelligent Computer-Aided Training System, for such ambitious manned programs as Space Station Freedom, which employs five different modules to constitute its job-independent training architecture.

Trimodal spectra for high discrimination of benign and malignant prostate tissue

NASA Astrophysics Data System (ADS)

Al Salhi, Mohamad; Masilamani, Vadivel; Trinka, Vijmasi; Rabah, Danny; Al Turki, Mohammed R.

2011-02-01

High false positives and over diagnosis is a major problem with management of prostate cancer. A non-invasive or a minimally invasive technique to accurately distinguish malignant prostate cancers from benign tumors will be extremely helpful to overcome this problem. In this paper, we had used three different fluorescence spectroscopy techniques viz., Fluorescence Emission Spectrum (FES), Stokes' Shift Spectrum (SSS) and Reflectance Spectrum (RS) to discriminate benign prostate tumor tissues (N=12) and malignant prostate cancer tissues (N=8). These fluorescence techniques were used to determine the relative concentration of naturally occurring biomolecules such as tryptophan, elastin, NADH and flavin which are found to be out of proportion in cancer tissues. Our studies show that combining all three techniques, benign and malignant prostate tissues could be classified with accuracy greater than 90%. This preliminary report is based on in vitro spectroscopy analysis. However, by employing fluorescence endoscopy techniques, this can be extended to in vivo analysis as well. This technique has the potential to identify malignant prostate tissues without surgery.

Survey of attitudes, materials and methods employed in endodontic treatment by general dental practitioners in North Jordan

PubMed Central

Al-Omari, Wael M

2004-01-01

Background General dental practitioners provide the majority of endodontic treatment in Jordan. The aim of this study was to gather information on the methods, materials and attitudes employed in root canal treatment by dentists in North Jordan, in order to evaluate and improve the quality of current practice. Methods A questionnaire was posted to all registered general dental practitioners working in private practice in Irbid Governate in North Jordan (n = 181). The questionnaire included information on methods, materials and techniques used in endodontic treatment. Results Reply rate was 72% (n = 131). The results demonstrated that only five dentists used rubber dam occasionally and not routinely. The majority used cotton rolls for isolation solely or in combination with a high volume saliva ejector (n = 116). The most widely used irrigants were sodium hypochlorite and hydrogen peroxide, which were used by 32.9% (n = 43) and 33.6% (n = 44) of the respondents, respectively. Forty eight percent of the respondents (n = 61) used the cold lateral condensation technique for canal obturation, 31.3% (n = 41) used single cone, 9.9% (n = 13) used vertical condensation and 12.2% (n = 16) used paste or cement only for the obturation. The majority used zinc oxide eugenol as a sealer (72.5%). All, but one, respondents used hand instruments for canal preparation and the technique of choice was step back (52.7%). More than 50% (n = 70) of the dentists took one radiograph for determining the working length, whilst 22.9% (n = 30) did not take any radiograph at all. Most practitioners performed treatment in three visits for teeth with two or more root canals, and in two visits for teeth with a single root canal. Conclusions This study indicates that dentists practicing in North Jordan do not comply with international quality standards and do not use recently introduced techniques. Many clinicians never take a radiograph for determining the working length and never used rubber dam or intra-canal medicaments. PMID:15361258

Addressing Obesity in the Workplace: The Role of Employers

PubMed Central

Heinen, Luann; Darling, Helen

2009-01-01

Context: Employers have pursued many strategies over the years to control health care costs and improve care. Disappointed by efforts to manage costs through the use of insurance-related techniques (e.g., prior authorization, restricted provider networks), employers have also begun to try to manage health by addressing their employees' key lifestyle risks. Reducing obesity (along with tobacco use and inactivity) is a priority for employers seeking to lower the incidence and severity of chronic illness and the associated demand for health services. Methods: This article describes the employer's perspective on the cost impact of obesity, discusses current practices in employer-sponsored wellness and weight management programs, provides examples from U.S. companies illustrating key points of employers' leverage and opportunities, and suggests policy directions to support the expansion of employers' initiatives, especially for smaller employers. Findings: Researchers and policymakers often overlook the extensive efforts and considerable impact of employer-sponsored wellness and health improvement programs. Greater focus on opportunities in the workplace is merited, however, for the evidence base supporting the economic and health impacts of employer-sponsored health promotion and wellness is growing, although not as quickly as the experience base of large employers. Conclusions: Public and private employers can serve their own economic interests by addressing obesity. Health care organizations, particularly hospitals, as well as public employers can be important role models. Policy development is needed to accelerate change, especially for smaller employers (those with fewer than 500 employees), which represent the majority of U.S. employers and are far less likely to offer health promotion programs. PMID:19298417

Addressing obesity in the workplace: the role of employers.

PubMed

Heinen, LuAnn; Darling, Helen

2009-03-01

Employers have pursued many strategies over the years to control health care costs and improve care. Disappointed by efforts to manage costs through the use of insurance-related techniques (e.g., prior authorization, restricted provider networks), employers have also begun to try to manage health by addressing their employees' key lifestyle risks. Reducing obesity (along with tobacco use and inactivity) is a priority for employers seeking to lower the incidence and severity of chronic illness and the associated demand for health services. This article describes the employer's perspective on the cost impact of obesity, discusses current practices in employer-sponsored wellness and weight management programs, provides examples from U.S. companies illustrating key points of employers' leverage and opportunities, and suggests policy directions to support the expansion of employers' initiatives, especially for smaller employers. Researchers and policymakers often overlook the extensive efforts and considerable impact of employer-sponsored wellness and health improvement programs. Greater focus on opportunities in the workplace is merited, however, for the evidence base supporting the economic and health impacts of employer-sponsored health promotion and wellness is growing, although not as quickly as the experience base of large employers. Public and private employers can serve their own economic interests by addressing obesity. Health care organizations, particularly hospitals, as well as public employers can be important role models. Policy development is needed to accelerate change, especially for smaller employers (those with fewer than 500 employees), which represent the majority of U.S. employers and are far less likely to offer health promotion programs.

The right stuff ... meeting your customer needs.

PubMed

Rubin, P; Carrington, S

1999-11-01

Meeting (and exceeding) your customers' needs is a requirement for competing in the current business world. New tools and techniques must be employed to deal with the rapidly changing global environment. This article describes the success of a global supply chain integration project for a division of a large multinational corporation. A state-of-the-art ERP software package was implemented in conjunction with major process changes to improve the organization's ability to promise and deliver product to their customers.

Career satisfaction of Jordanian dental hygienists.

PubMed

Malkawi, Z A

2016-11-01

The aim of this study was to determine the factors that affect Jordanian dental hygienists with their career satisfaction including financial issues, employment settings and policies. Randomized sample of 102 dental hygienists with a bachelor's degree were selected from the entire population of Jordanian dental hygienists. Participants received a cover letter with a questionnaire. Findings were analysed using descriptive data techniques. Chi-square test was used to determine the statistically significant differences across demographic variables and career satisfaction's factors. About 22.5% of the participants are not working as dental hygienist. Dental hygiene profession in Jordan includes predominantly (74.0%) females. Majority of them (51.9%) were employed in JUST, and minority (6.3%) in MOH. Most of them (56.4%) were aged 24-29 years old, and mostly 62.2% with ≤1 child. About 53.1% employed by general dentist. Almost 35.3% had ≥4 years' job experience. Majority (47.6%) expressed high level of satisfaction with dental materials and equipment to practice work; however, only 2.0% expressed very high level of satisfaction with employment policies. Almost 32.4% expressed low level of satisfaction with salary level. Minority (2.0%) expressed dissatisfaction with quality of dentist's work. Statistically significant association was found between workplace, and dental materials and equipment to practice work, salary level, employment policies (P = 0.003, P = 0.003, P = 0.026), and number of children with flexibility in work hours (P = 0.001). Jordanian dental hygienists' workplacesatisfaction w as significantly associated with dental materials and equipment to practice work, salary level, and employment policies. Understanding the working patterns of dental hygienists in Jordan is important to increase their career satisfaction levels. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Recent developments in low cost silicon solar cells for terrestrial applications. [sheet production methods

NASA Technical Reports Server (NTRS)

Leipold, M. H.

1978-01-01

A variety of techniques may be used for photovoltaic energy systems. Concentrated or not concentrated sunlight may be employed, and a number of materials can be used, including silicon, gallium arsenide, cadmium sulfide, and cadmium telluride. Most of the experience, however, has been obtained with silicon cells employed without sunlight concentration. An industrial base exists at present for producing solar cells at a price in the range from $15 to $30 per peak watt. A major federal program has the objective to reduce the price of power provided by silicon solar systems to approximately $1 per peak watt in the early 1980's and $0.50 per watt by 1986. The approaches considered for achieving this objective are discussed.

Insurer and employer views on pediatric obesity treatment: a qualitative study.

PubMed

Hampl, S E; Davis, A M; Sampilo, M L; Stephens, K L; Dean, K

2013-04-01

The effectiveness of group-based comprehensive, multidisciplinary (stage 3) pediatric weight management programs is backed by a growing body of literature, yet insurance coverage of these programs is scarce to nonexistent, limiting their reach and long-term survival. The objective of this study was to better understand the perspectives of insurers and large employers on the issue of group-based treatment coverage. The authors performed a qualitative study utilizing structured interviews with these stakeholders, following accepted techniques. Six major themes emerged: cost, program effectiveness, corporate social responsibility, secondary parental (employee) benefits, coverage options and new benefit determination. Future efforts to secure payment for group-based pediatric weight management programs should address these key themes. Copyright © 2012 The Obesity Society.

The program at JPL to investigate the nuclear interaction of RTG's with scientific instruments on deep space probes

NASA Technical Reports Server (NTRS)

Truscello, V.

1972-01-01

A major concern in the integration of a radioisotope thermoelectric generator (RTG) with a spacecraft designed to explore the outer planets is the effect of the emitted radiation on the normal operation of scientific instruments. The necessary techniques and tools developed to allow accurate calculation of the neutron and gamma spectrum emanating from the RTG. The specific sources of radiation were identified and quantified. Monte Carlo techniques are then employed to perform the nuclear transport calculations. The results of these studies are presented. An extensive experimental program was initiated to measure the response of a number of scientific components to the nuclear radiation.

Simulation techniques in hyperthermia treatment planning

PubMed Central

Paulides, MM; Stauffer, PR; Neufeld, E; Maccarini, P; Kyriakou, A; Canters, RAM; Diederich, C; Bakker, JF; Van Rhoon, GC

2013-01-01

Clinical trials have shown that hyperthermia (HT), i.e. an increase of tissue temperature to 39-44°C, significantly enhance radiotherapy and chemotherapy effectiveness (1). Driven by the developments in computational techniques and computing power, personalized hyperthermia treatment planning (HTP) has matured and has become a powerful tool for optimizing treatment quality. Electromagnetic, ultrasound, and thermal simulations using realistic clinical setups are now being performed to achieve patient-specific treatment optimization. In addition, extensive studies aimed to properly implement novel HT tools and techniques, and to assess the quality of HT, are becoming more common. In this paper, we review the simulation tools and techniques developed for clinical hyperthermia, and evaluate their current status on the path from “model” to “clinic”. In addition, we illustrate the major techniques employed for validation and optimization. HTP has become an essential tool for improvement, control, and assessment of HT treatment quality. As such, it plays a pivotal role in the quest to establish HT as an efficacious addition to multi-modality treatment of cancer. PMID:23672453

Enzyme assisted extraction of biomolecules as an approach to novel extraction technology: A review.

PubMed

Nadar, Shamraja S; Rao, Priyanka; Rathod, Virendra K

2018-06-01

An interest in the development of extraction techniques of biomolecules from various natural sources has increased in recent years due to their potential applications particularly for food and nutraceutical purposes. The presence of polysaccharides such as hemicelluloses, starch, pectin inside the cell wall, reduces the extraction efficiency of conventional extraction techniques. Conventional techniques also suffer from low extraction yields, time inefficiency and inferior extract quality due to traces of organic solvents present in them. Hence, there is a need of the green and novel extraction methods to recover biomolecules. The present review provides a holistic insight to various aspects related to enzyme aided extraction. Applications of enzymes in the recovery of various biomolecules such as polyphenols, oils, polysaccharides, flavours and colorants have been highlighted. Additionally, the employment of hyphenated extraction technologies can overcome some of the major drawbacks of enzyme based extraction such as longer extraction time and immoderate use of solvents. This review also includes hyphenated intensification techniques by coupling conventional methods with ultrasound, microwave, high pressure and supercritical carbon dioxide. The last section gives an insight on application of enzyme immobilization as a strategy for large scale extraction. Immobilization of enzymes on magnetic nanoparticles can be employed to enhance the operational performance of the system by multiple use of expensive enzymes making them industrially and economically feasible. Copyright © 2018 Elsevier Ltd. All rights reserved.

[Methods of cholesterol determination: conventional procedure or "dry chemistry"?].

PubMed

Riesen, W; Keller, H

1990-06-01

The search for the cardiovascular risk factor cholesterol should essentially be done in the physicians' laboratory. The majority of such analyses is performed by 'dry' chemistry tests. This review compares this technique with conventional methods for the determination of cholesterol. The reagents and the reaction mechanisms are principally the same for both techniques, i.e. fully enzymatic methods are used. In 'dry' chemistry the reagents are fixed on a solid carrier. The reactive state is provided by the liquid of the specimen. Two principles are employed: the technique of strips which is already utilised in urinary analysis and the system of multiple film layers as it is common in color-film technique. Three already introduced systems are discussed: the Seralyzer (Ames), the Ektachem (Kodak), and the Reflotron (Boehringer, Mannheim), and one system which is still in evaluation (the Clinistat, Ames). All the systems give a good agreement provided that they are operated by well-trained operators. Problems arise with quality control, since matrix effects are particularly important. The exactitude of the results depends on the calibration. Both, the Reflotron and the Clinistat are calibrated by the manufactories himself, the employer has no influence and is entirely dependent on the reliability of the producer. Although clinical chemistry analyses are facilitated by 'dry' chemistry it is by no means devoid of risks because the errors are more difficult to recognize.

A preclustering-based ensemble learning technique for acute appendicitis diagnoses.

PubMed

Lee, Yen-Hsien; Hu, Paul Jen-Hwa; Cheng, Tsang-Hsiang; Huang, Te-Chia; Chuang, Wei-Yao

2013-06-01

Acute appendicitis is a common medical condition, whose effective, timely diagnosis can be difficult. A missed diagnosis not only puts the patient in danger but also requires additional resources for corrective treatments. An acute appendicitis diagnosis constitutes a classification problem, for which a further fundamental challenge pertains to the skewed outcome class distribution of instances in the training sample. A preclustering-based ensemble learning (PEL) technique aims to address the associated imbalanced sample learning problems and thereby support the timely, accurate diagnosis of acute appendicitis. The proposed PEL technique employs undersampling to reduce the number of majority-class instances in a training sample, uses preclustering to group similar majority-class instances into multiple groups, and selects from each group representative instances to create more balanced samples. The PEL technique thereby reduces potential information loss from random undersampling. It also takes advantage of ensemble learning to improve performance. We empirically evaluate this proposed technique with 574 clinical cases obtained from a comprehensive tertiary hospital in southern Taiwan, using several prevalent techniques and a salient scoring system as benchmarks. The comparative results show that PEL is more effective and less biased than any benchmarks. The proposed PEL technique seems more sensitive to identifying positive acute appendicitis than the commonly used Alvarado scoring system and exhibits higher specificity in identifying negative acute appendicitis. In addition, the sensitivity and specificity values of PEL appear higher than those of the investigated benchmarks that follow the resampling approach. Our analysis suggests PEL benefits from the more representative majority-class instances in the training sample. According to our overall evaluation results, PEL records the best overall performance, and its area under the curve measure reaches 0.619. The PEL technique is capable of addressing imbalanced sample learning associated with acute appendicitis diagnosis. Our evaluation results suggest PEL is less biased toward a positive or negative class than the investigated benchmark techniques. In addition, our results indicate the overall effectiveness of the proposed technique, compared with prevalent scoring systems or salient classification techniques that follow the resampling approach. Copyright © 2013 Elsevier B.V. All rights reserved.

Advanced optical position sensors for magnetically suspended wind tunnel models

NASA Technical Reports Server (NTRS)

Lafleur, S.

1985-01-01

A major concern to aerodynamicists has been the corruption of wind tunnel test data by model support structures, such as stings or struts. A technique for magnetically suspending wind tunnel models was considered by Tournier and Laurenceau (1957) in order to overcome this problem. This technique is now implemented with the aid of a Large Magnetic Suspension and Balance System (LMSBS) and advanced position sensors for measuring model attitude and position within the test section. Two different optical position sensors are discussed, taking into account a device based on the use of linear CCD arrays, and a device utilizing area CID cameras. Current techniques in image processing have been employed to develop target tracking algorithms capable of subpixel resolution for the sensors. The algorithms are discussed in detail, and some preliminary test results are reported.

Remote sensing for urban planning

NASA Technical Reports Server (NTRS)

Davis, Bruce A.; Schmidt, Nicholas; Jensen, John R.; Cowen, Dave J.; Halls, Joanne; Narumalani, Sunil; Burgess, Bryan

1994-01-01

Utility companies are challenged to provide services to a highly dynamic customer base. With factory closures and shifts in employment becoming a routine occurrence, the utility industry must develop new techniques to maintain records and plan for expected growth. BellSouth Telecommunications, the largest of the Bell telephone companies, currently serves over 13 million residences and 2 million commercial customers. Tracking the movement of customers and scheduling the delivery of service are major tasks for BellSouth that require intensive manpower and sophisticated information management techniques. Through NASA's Commercial Remote Sensing Program Office, BellSouth is investigating the utility of remote sensing and geographic information system techniques to forecast residential development. This paper highlights the initial results of this project, which indicate a high correlation between the U.S. Bureau of Census block group statistics and statistics derived from remote sensing data.

Managing Problems Before Problems Manage You.

PubMed

Grigsby, Jim

2015-01-01

Every day we face problems, both personal and professional, and our initial reaction determines how well we solve those problems. Whether a problem is minor or major, short-term or lingering, there are techniques we can employ to help manage the problem and the problem-solving process. This article, based on my book Don't Tick Off The Gators! Managing Problems Before Problems Manage You, presents 12 different concepts for managing problems, not "cookie cutter" solutions, but different ideas that you can apply as they fit your circumstances.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Y.; Tobias, B.; Chang, Y. -T.

Electron cyclotron emission (ECE) imaging is a passive radiometric technique that measures electron temperature fluctuations; and microwave imaging reflectometry (MIR) is an active radar imaging technique that measures electron density fluctuations. The microwave imaging diagnostic instruments employing these techniques have made important contributions to fusion science and have been adopted at major fusion facilities worldwide including DIII-D, EAST, ASDEX Upgrade, HL-2A, KSTAR, LHD, and J-TEXT. In this paper, we describe the development status of three major technological advancements: custom mm-wave integrated circuits (ICs), digital beamforming (DBF), and synthetic diagnostic modeling (SDM). These also have the potential to greatly advance microwavemore » fusion plasma imaging, enabling compact and low-noise transceiver systems with real-time, fast tracking ability to address critical fusion physics issues, including ELM suppression and disruptions in the ITER baseline scenario, naturally ELM-free states such as QH-mode, and energetic particle confinement (i.e. Alfven eigenmode stability) in high-performance regimes that include steady-state and advanced tokamak scenarios. Furthermore, these systems are fully compatible with today's most challenging non-inductive heating and current drive systems and capable of operating in harsh environments, making them the ideal approach for diagnosing long-pulse and steady-state tokamaks.« less

Hidden explosives detector employing pulsed neutron and x-ray interrogation

DOEpatents

Schultz, F.J.; Caldwell, J.T.

1993-04-06

Methods and systems for the detection of small amounts of modern, highly-explosive nitrogen-based explosives, such as plastic explosives, hidden in airline baggage. Several techniques are employed either individually or combined in a hybrid system. One technique employed in combination is X-ray imaging. Another technique is interrogation with a pulsed neutron source in a two-phase mode of operation to image both nitrogen and oxygen densities. Another technique employed in combination is neutron interrogation to form a hydrogen density image or three-dimensional map. In addition, deliberately-placed neutron-absorbing materials can be detected.

Hidden explosives detector employing pulsed neutron and x-ray interrogation

DOEpatents

Schultz, Frederick J.; Caldwell, John T.

1993-01-01

Methods and systems for the detection of small amounts of modern, highly-explosive nitrogen-based explosives, such as plastic explosives, hidden in airline baggage. Several techniques are employed either individually or combined in a hybrid system. One technique employed in combination is X-ray imaging. Another technique is interrogation with a pulsed neutron source in a two-phase mode of operation to image both nitrogen and oxygen densities. Another technique employed in combination is neutron interrogation to form a hydrogen density image or three-dimensional map. In addition, deliberately-placed neutron-absorbing materials can be detected.

Current opinion on auricular reconstruction.

PubMed

Sivayoham, Eason; Woolford, Tim J

2012-08-01

To review the current practice in the field of auricular reconstruction and to highlight the recent advances reported in the medical literature. The majority of surgeons who perform auricular reconstruction continue to employ the well-established techniques developed by Brent and Nagata. Surgery takes between two and four stages, with the initial stage being construction of a framework of autogenous rib cartilage which is implanted into a subcutaneous pocket. Several modifications of these techniques have been reported. More recently, synthetic frameworks have been employed instead of autogenous rib cartilage. For this procedure, the implant is generally covered with a temporoparietal flap and a skin graft at the first stage of surgery. Tissue engineering is a rapidly developing field, and there have been several articles related to the field of auricular reconstruction. These show great potential to offer a solution to the challenge associated with construction of a viable autogenous cartilage framework, whilst avoiding donor-site morbidity. This article gives an overview of the current practice in the field of auricular reconstruction and summarizes the recent surgical developments and relevant tissue engineering research.

Biotechnology and apple breeding in Japan

PubMed Central

Igarashi, Megumi; Hatsuyama, Yoshimichi; Harada, Takeo; Fukasawa-Akada, Tomoko

2016-01-01

Apple is a fruit crop of significant economic importance, and breeders world wide continue to develop novel cultivars with improved characteristics. The lengthy juvenile period and the large field space required to grow apple populations have imposed major limitations on breeding. Various molecular biological techniques have been employed to make apple breeding easier. Transgenic technology has facilitated the development of apples with resistance to fungal or bacterial diseases, improved fruit quality, or root stocks with better rooting or dwarfing ability. DNA markers for disease resistance (scab, powdery mildew, fire-blight, Alternaria blotch) and fruit skin color have also been developed, and marker-assisted selection (MAS) has been employed in breeding programs. In the last decade, genomic sequences and chromosome maps of various cultivars have become available, allowing the development of large SNP arrays, enabling efficient QTL mapping and genomic selection (GS). In recent years, new technologies for genetic improvement, such as trans-grafting, virus vectors, and genome-editing, have emerged. Using these techniques, no foreign genes are present in the final product, and some of them show considerable promise for application to apple breeding. PMID:27069388

Enhanced Performance of Thin Film Composite Forward Osmosis Membrane by Chemical Post-Treatment

NASA Astrophysics Data System (ADS)

Liu, Zheng; Chen, Jiangrong; Cao, Zhen; Wang, Jian; Guo, Chungang

2018-01-01

Forward osmosis is an attractive technique in water purification and desalination fields. Enhancement of the forward osmosis membrane performance is essential to the application of this technique. In this study, an optimized chemical post-treatment approach which was used to improve RO membrane performance was employed for enhancing water flux of thin film composite forward osmosis membrane. Home-made polysulfide-based forward osmosis membrane was prepared and nitric acid, sulfuric acid, ethanol, 2-propanol were employed as post-treatment solutions. After a short-term treatment, all the membrane samples manifested water flux enhancement compared with their untreated counterparts. Over 50% increase of water flux had been obtained by ethanol solution treatment. The swelling, changes of hydrophobicity and solvency in both active layer and substrate were verified as the major causes for the enhancement of the water flux. It is noted that the treatment time and solution concentration should be controlled to get both appropriate water flux and reverse salt flux. The results obtained in this study will be useful for further FO membrane development and application.

Biotechnology and apple breeding in Japan.

PubMed

Igarashi, Megumi; Hatsuyama, Yoshimichi; Harada, Takeo; Fukasawa-Akada, Tomoko

2016-01-01

Apple is a fruit crop of significant economic importance, and breeders world wide continue to develop novel cultivars with improved characteristics. The lengthy juvenile period and the large field space required to grow apple populations have imposed major limitations on breeding. Various molecular biological techniques have been employed to make apple breeding easier. Transgenic technology has facilitated the development of apples with resistance to fungal or bacterial diseases, improved fruit quality, or root stocks with better rooting or dwarfing ability. DNA markers for disease resistance (scab, powdery mildew, fire-blight, Alternaria blotch) and fruit skin color have also been developed, and marker-assisted selection (MAS) has been employed in breeding programs. In the last decade, genomic sequences and chromosome maps of various cultivars have become available, allowing the development of large SNP arrays, enabling efficient QTL mapping and genomic selection (GS). In recent years, new technologies for genetic improvement, such as trans-grafting, virus vectors, and genome-editing, have emerged. Using these techniques, no foreign genes are present in the final product, and some of them show considerable promise for application to apple breeding.

Uncovered secret of a Vasseur-Tramond wax model.

PubMed

Pastor, J F; Gutiérrez, B; Montes, J M; Ballestriero, R

2016-01-01

The technique of anatomical wax modelling reached its heyday in Italy during the 18th century, through a fruitful collaboration between sculptors and anatomists. It soon spread to other countries, and prestigious schools were created in England, France, Spain and Austria. Paris subsequently replaced Italy as the major centre of manufacture, and anatomical waxes were created there from the mid-19th century in workshops such as that of Vasseur-Tramond. This workshop began to sell waxes to European Faculties of Medicine and Schools of Surgery around 1880. Little is known of the technique employed in the creation of such artefacts as this was deemed a professional secret. To gain some insight into the methods of construction, we have studied a Vasseur-Tramond wax model in the Valladolid University Anatomy Museum, Spain, by means of multi-slice computerised tomography and X-ray analysis by means of environmental scanning electron microscopy. Scanning electron microscopy was used to examine the hair. These results have revealed some of the methods used to make these anatomical models and the materials employed. © 2015 Anatomical Society.

Reliability of horizontal and vertical tube shift techniques in the localisation of supernumerary teeth.

PubMed

Mallineni, S K; Anthonappa, R P; King, N M

2016-12-01

To assess the reliability of the vertical tube shift technique (VTST) and horizontal tube shift technique (HTST) for the localisation of unerupted supernumerary teeth (ST) in the anterior region of the maxilla. A convenience sample of 83 patients who attended a major teaching hospital because of unerupted ST was selected. Only non-syndromic patients with ST and who had complete clinical and radiographic and surgical records were included in the study. Ten examiners independently rated the paired set of radiographs for each technique. Chi-square test, paired t test and kappa statistics were employed to assess the intra- and inter-examiner reliability. Paired sets of 1660 radiographs (830 pairs for each technique) were available for the analysis. The overall sensitivity for VTST and HTST was 80.6 and 72.1% respectively, with slight inter-examiner and good intra-examiner reliability. Statistically significant differences were evident between the two localisation techniques (p < 0.05). Localisation of unerupted ST using VTST was more successful than HTST in the anterior region of the maxilla.

A georeferenced Landsat digital database for forest insect-damage assessment

NASA Technical Reports Server (NTRS)

Williams, D. L.; Nelson, R. F.; Dottavio, C. L.

1985-01-01

In 1869, the gypsy moth caterpillar was introduced in the U.S. in connection with the experiments of a French scientist. Throughout the insect's period of establishment, gypsy moth populations have periodically increased to epidemic proportions. For programs concerned with preventing the insect's spread, it would be highly desirable to be able to employ a survey technique which could provide timely, accurate, and standardized assessments at a reasonable cost. A project was, therefore, initiated with the aim to demonstrate the usefulness of satellite remotely sensed data for monitoring the insect defoliation of hardwood forests in Pennsylvania. A major effort within this project involved the development of a map-registered Landsat digital database. A complete description of the database developed is provided along with information regarding the employed data management system.

Applications of Microfluidics in Quantitative Biology.

PubMed

Bai, Yang; Gao, Meng; Wen, Lingling; He, Caiyun; Chen, Yuan; Liu, Chenli; Fu, Xiongfei; Huang, Shuqiang

2018-05-01

Quantitative biology is dedicated to taking advantage of quantitative reasoning and advanced engineering technologies to make biology more predictable. Microfluidics, as an emerging technique, provides new approaches to precisely control fluidic conditions on small scales and collect data in high-throughput and quantitative manners. In this review, the authors present the relevant applications of microfluidics to quantitative biology based on two major categories (channel-based microfluidics and droplet-based microfluidics), and their typical features. We also envision some other microfluidic techniques that may not be employed in quantitative biology right now, but have great potential in the near future. © 2017 Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences. Biotechnology Journal Published by Wiley-VCH Verlag GmbH & Co. KGaA.

Role and Evaluation of Interlaboratory Comparison Results in Laboratory Accreditation

NASA Astrophysics Data System (ADS)

Bode, P.

2008-08-01

Participation in interlaboratory comparisons provides laboratories an opportunity for independent assessment of their analytical performance, both in absolute way and in comparison with those by other techniques. However, such comparisons are hindered by differences in the way laboratories participate, e.g. at best measurement capability or under routine conditions. Neutron activation analysis laboratories, determining total mass fractions, often see themselves classified as `outliers' since the majority of other participants employ techniques with incomplete digestion methods. These considerations are discussed in relation to the way results from interlaboratory comparisons are evaluated by accreditation bodies following the requirements of Clause 5.9.1 of the ISO/IEC 17025:2005. The discussion and conclusions come largely forth from experiences in the author's own laboratory.

Optimisation of Critical Infrastructure Protection: The SiVe Project on Airport Security

NASA Astrophysics Data System (ADS)

Breiing, Marcus; Cole, Mara; D'Avanzo, John; Geiger, Gebhard; Goldner, Sascha; Kuhlmann, Andreas; Lorenz, Claudia; Papproth, Alf; Petzel, Erhard; Schwetje, Oliver

This paper outlines the scientific goals, ongoing work and first results of the SiVe research project on critical infrastructure security. The methodology is generic while pilot studies are chosen from airport security. The outline proceeds in three major steps, (1) building a threat scenario, (2) development of simulation models as scenario refinements, and (3) assessment of alternatives. Advanced techniques of systems analysis and simulation are employed to model relevant airport structures and processes as well as offences. Computer experiments are carried out to compare and optimise alternative solutions. The optimality analyses draw on approaches to quantitative risk assessment recently developed in the operational sciences. To exploit the advantages of the various techniques, an integrated simulation workbench is build up in the project.

Contemporary practice in forensic odontology

PubMed Central

Gupta, Shalini; Agnihotri, Archana; Chandra, Akhilesh; Gupta, Om Prakash

2014-01-01

Forensic odontology plays a major role in the identification of those individuals who cannot be identified visually or by other means. The unique nature of dental anatomy and placement of custom restorations ensure accuracy when the techniques are correctly employed. It is evident that identification of victims in accidents and natural calamities is of utmost importance and is a challenging task. The teeth may also be used as weapons and under certain circumstances; they may provide information regarding the identity of the biter. Dental professionals play a major role in keeping accurate dental records and providing all necessary information so that legal authorities may recognize malpractices, negligence, fraud child abuse and also, identify an individual. In this article, we will discuss such evolvement of the subject. PMID:25328306

Nanostructured materials: A novel approach to enhanced performance. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Korth, G.E.; Froes, F.H.; Suryanarayana, C.

Nanostuctured materials are an emerging class of materials that can exhibit physical and mechanical characteristics often exceeding those exhibited by conventional course grained materials. A number of different techniques can be employed to produce these materials. In this program, the synthesis methods were (a) mechanical alloying , (b) physical vapor deposition, and (c) plasma processing. The physical vapor deposition and plasma processing were discontinued after initial testing with subsequent efforts focused on mechanical alloying. The major emphasis of the program was on the synthesis, consolidation, and characterization of nanostructured Al-Fe, Ti-Al, Ti-Al-Nb, and Fe-Al by alloying intermetallics with a viewmore » to increase their ductilities. The major findings of this project are reported.« less

Mitigation of stress: new treatment alternatives.

PubMed

Subhani, Ahmad Rauf; Kamel, Nidal; Mohamad Saad, Mohamad Naufal; Nandagopal, Nanda; Kang, Kenneth; Malik, Aamir Saeed

2018-02-01

Complaints of stress are common in modern life. Psychological stress is a major cause of lifestyle-related issues, contributing to poor quality of life. Chronic stress impedes brain function, causing impairment of many executive functions, including working memory, decision making and attentional control. The current study sought to describe newly developed stress mitigation techniques, and their influence on autonomic and endocrine functions. The literature search revealed that the most frequently studied technique for stress mitigation was biofeedback (BFB). However, evidence suggests that neurofeedback (NFB) and noninvasive brain stimulation (NIBS) could potentially provide appropriate approaches. We found that recent studies of BFB methods have typically used measures of heart rate variability, respiration and skin conductance. In contrast, studies of NFB methods have typically utilized neurocomputation techniques employing electroencephalography, functional magnetic resonance imaging and near infrared spectroscopy. NIBS studies have typically utilized transcranial direct current stimulation methods. Mitigation of stress is a challenging but important research target for improving quality of life.

Daily pan evaporation modelling using a neuro-fuzzy computing technique

NASA Astrophysics Data System (ADS)

Kişi, Özgür

2006-10-01

SummaryEvaporation, as a major component of the hydrologic cycle, is important in water resources development and management. This paper investigates the abilities of neuro-fuzzy (NF) technique to improve the accuracy of daily evaporation estimation. Five different NF models comprising various combinations of daily climatic variables, that is, air temperature, solar radiation, wind speed, pressure and humidity are developed to evaluate degree of effect of each of these variables on evaporation. A comparison is made between the estimates provided by the NF model and the artificial neural networks (ANNs). The Stephens-Stewart (SS) method is also considered for the comparison. Various statistic measures are used to evaluate the performance of the models. Based on the comparisons, it was found that the NF computing technique could be employed successfully in modelling evaporation process from the available climatic data. The ANN also found to perform better than the SS method.

An Improved Computational Technique for Calculating Electromagnetic Forces and Power Absorptions Generated in Spherical and Deformed Body in Levitation Melting Devices

NASA Technical Reports Server (NTRS)

Zong, Jin-Ho; Szekely, Julian; Schwartz, Elliot

1992-01-01

An improved computational technique for calculating the electromagnetic force field, the power absorption and the deformation of an electromagnetically levitated metal sample is described. The technique is based on the volume integral method, but represents a substantial refinement; the coordinate transformation employed allows the efficient treatment of a broad class of rotationally symmetrical bodies. Computed results are presented to represent the behavior of levitation melted metal samples in a multi-coil, multi-frequency levitation unit to be used in microgravity experiments. The theoretical predictions are compared with both analytical solutions and with the results or previous computational efforts for the spherical samples and the agreement has been very good. The treatment of problems involving deformed surfaces and actually predicting the deformed shape of the specimens breaks new ground and should be the major usefulness of the proposed method.

Software error detection

NASA Technical Reports Server (NTRS)

Buechler, W.; Tucker, A. G.

1981-01-01

Several methods were employed to detect both the occurrence and source of errors in the operational software of the AN/SLQ-32. A large embedded real time electronic warfare command and control system for the ROLM 1606 computer are presented. The ROLM computer provides information about invalid addressing, improper use of privileged instructions, stack overflows, and unimplemented instructions. Additionally, software techniques were developed to detect invalid jumps, indices out of range, infinte loops, stack underflows, and field size errors. Finally, data are saved to provide information about the status of the system when an error is detected. This information includes I/O buffers, interrupt counts, stack contents, and recently passed locations. The various errors detected, techniques to assist in debugging problems, and segment simulation on a nontarget computer are discussed. These error detection techniques were a major factor in the success of finding the primary cause of error in 98% of over 500 system dumps.

Operational flow visualization techniques in the Langley Unitary Plan Wind Tunnel

NASA Technical Reports Server (NTRS)

Corlett, W. A.

1982-01-01

The unitary plan wind tunnel (UPWT) uses in daily operation are shown. New ideas for improving the quality of established flow visualization methods are developed and programs on promising new flow visualization techniques are pursued. The unitary plan wind tunnel is a supersonic facility, referred to as a production facility, although the majority of tests are inhouse basic research investigations. The facility has two 4 ft. by 4 ft. test sections which span a Mach range from 1.5 to 4.6. The cost of operation is about $10 per minute. Problems are the time required for a flow visualization test setup and investigation costs and the ability to obtain consistently repeatable results. Examples of sublimation, vapor screen, oil flow, minitufts, schlieren, and shadowgraphs taken in UPWT are presented. All tests in UPWT employ one or more of the flow visualization techniques.

De-embedding technique for accurate modeling of compact 3D MMIC CPW transmission lines

NASA Astrophysics Data System (ADS)

Pohan, U. H.; KKyabaggu, P. B.; Sinulingga, E. P.

2018-02-01

Requirement for high-density and high-functionality microwave and millimeter-wave circuits have led to the innovative circuit architectures such as three-dimensional multilayer MMICs. The major advantage of the multilayer techniques is that one can employ passive and active components based on CPW technology. In this work, MMIC Coplanar Waveguide(CPW)components such as Transmission Line (TL) are modeled in their 3D layouts. Main characteristics of CPWTL suffered from the probe pads’ parasitic and resonant frequency effects have been studied. By understanding the parasitic effects, then the novel de-embedding technique are developed accurately in order to predict high frequency characteristics of the designed MMICs. The novel de-embedding technique has shown to be critical in reducing the probe pad parasitic significantly from the model. As results, high frequency characteristics of the designed MMICs have been presented with minimumparasitic effects of the probe pads. The de-embedding process optimises the determination of main characteristics of Compact 3D MMIC CPW transmission lines.

Environmental scanning electron microscopy in cell biology.

PubMed

McGregor, J E; Staniewicz, L T L; Guthrie Neé Kirk, S E; Donald, A M

2013-01-01

Environmental scanning electron microscopy (ESEM) (1) is an imaging technique which allows hydrated, insulating samples to be imaged under an electron beam. The resolution afforded by this technique is higher than conventional optical microscopy but lower than conventional scanning electron microscopy (CSEM). The major advantage of the technique is the minimal sample preparation needed, making ESEM quick to use and the images less susceptible to the artifacts that the extensive sample preparation usually required for CSEM may introduce. Careful manipulation of both the humidity in the microscope chamber and the beam energy are nevertheless essential to prevent dehydration and beam damage artifacts. In some circumstances it is possible to image live cells in the ESEM (2).In the following sections we introduce the fundamental principles of ESEM imaging before presenting imaging protocols for plant epidermis, mammalian cells, and bacteria. In the first two cases samples are imaged using the secondary electron (topographic) signal, whereas a transmission technique is employed to image bacteria.

Engineering of Multifunctional Nanomaterials for Cancer Theranostics

NASA Astrophysics Data System (ADS)

Goel, Shreya

Development of novel imaging probes for cancer diagnosis is critical for early disease detection and management. The past two decades have witnessed a surge in the development and evolution of radiolabeled nanoparticles as a new frontier in personalized cancer nanomedicine. The dynamic synergism of positron emission tomography (PET) and nanotechnology combines the sensitivity and quantitative nature of PET with the multifunctionality and tunability of nanomaterials, which can help overcome certain key challenges in the field. Silica, "generally recognized as safe" (GRAS) by the Food and Drug Administration (FDA) of the United States, has emerged as one of the leading nanomaterials employed for molecular imaging and therapy of a wide variety of diseases, including cancer. However in vivo biodistribution and active targeting of silica-based nanomaterials has remained a relatively under explored area, based mainly on semi-quantitative techniques such as fluorescence imaging. In this dissertation, I explore the concept of radiolabeled silica nanoparticles for vasculature-targeted imaging of different tumor types. Both chelator-based and chelator-free radiolabeling techniques were employed for accurate and quantitative analysis of the in vivo pharmacokinetics of radiolabeled silica nanomaterials. (Chapters 2 and 3) The large surface area, ease of tunability and facile silica chemistry were employed to create multifunctional silica-based materials to simultaneously seek-and-treat cancers, by incorporating multiple components into a single nanoplatform. Photodynamic agent, porphyrin was loaded into the central cavity of hollow mesoporous silica nanoparticles, and the shell was decorated with photothermal nanoparticles, CuS, yielding a multimodal theranostic nanoplatform which could synergistically annihilate the tumor without relapse. (Chapter 4). A major hurdle in the successful clinical translation of nanomaterials is their rapid sequestration by the organs of the reticuloendothelial system (RES), mainly liver and spleen, and prolonged retention in the body, raising long-term toxicity concerns. To combat this issue, two approaches were employed; (i) Synthesis of biodegradable mesoporous silica nanoparticles (Chapter 5), and (ii) development of ultrasmall nanoparticles including renal clearable Au nanoparticles and hepatically cleared ultrasmall mesoporous silica nanoparticles (Chapter 6); for prolonged blood circulation, enhanced tumor uptake and rapid clearance from the body, enabling unprecedented tumor-to-normal tissue contrast. Overall, the reported studies explore the synergism of molecular imaging and therapy, and nanotechnology. While the application of nanomaterials in the former imparts multifunctionality to the molecular agent, allowing multimodal imaging and synergistic therapeutic regimes to be carried out simultaneously; molecular imaging techniques such as PET, allow accurate measurement of the in vivo pharmacokinetics of the nanomaterials, playing a major role towards their successful clinical translation. Further work will be required to better understand the in vivo biodistribution of both biodegradable and ultrasmall nanomaterials, and further employ them for early and specific detection of cancer, effective treatment and monitoring.

Ionization techniques in capillary electrophoresis-mass spectrometry: principles, design, and application.

PubMed

Hommerson, Paul; Khan, Amjad M; de Jong, Gerhardus J; Somsen, Govert W

2011-01-01

A major step forward in the development and application of capillary electrophoresis (CE) was its coupling to ESI-MS, first reported in 1987. More than two decades later, ESI has remained the principal ionization technique in CE-MS, but a number of other ionization techniques have also been implemented. In this review the state-of-the-art in the employment of soft ionization techniques for CE-MS is presented. First the fundamentals and general challenges of hyphenating conventional CE and microchip electrophoresis with MS are outlined. After elaborating on the characteristics and role of ESI, emphasis is put on alternative ionization techniques including sonic spray ionization (SSI), thermospray ionization (TSI), atmospheric pressure chemical ionization (APCI), atmospheric pressure photoionization (APPI), matrix-assisted laser desorption ionization (MALDI) and continuous-flow fast atom bombardment (CF-FAB). The principle of each ionization technique is outlined and the experimental set-ups of the CE-MS couplings are described. The strengths and limitations of each ionization technique with respect to CE-MS are discussed and the applicability of the various systems is illustrated by a number of typical examples. Copyright © 2011 Wiley Periodicals, Inc.

Transcranial magnetic stimulation for the treatment of major depression

PubMed Central

Janicak, Philip G; Dokucu, Mehmet E

2015-01-01

Major depression is often difficult to diagnose accurately. Even when the diagnosis is properly made, standard treatment approaches (eg, psychotherapy, medications, or their combination) are often inadequate to control acute symptoms or maintain initial benefit. Additional obstacles involve safety and tolerability problems, which frequently preclude an adequate course of treatment. This leaves an important gap in our ability to properly manage major depression in a substantial proportion of patients, leaving them vulnerable to ensuing complications (eg, employment-related disability, increased risk of suicide, comorbid medical disorders, and substance abuse). Thus, there is a need for more effective and better tolerated approaches. Transcranial magnetic stimulation is a neuromodulation technique increasingly used to partly fill this therapeutic void. In the context of treating depression, we critically review the development of transcranial magnetic stimulation, focusing on the results of controlled and pragmatic trials for depression, which consider its efficacy, safety, and tolerability. PMID:26170668

Near-infrared Raman spectroscopy for estimating biochemical changes associated with different pathological conditions of cervix

NASA Astrophysics Data System (ADS)

Daniel, Amuthachelvi; Prakasarao, Aruna; Ganesan, Singaravelu

2018-02-01

The molecular level changes associated with oncogenesis precede the morphological changes in cells and tissues. Hence molecular level diagnosis would promote early diagnosis of the disease. Raman spectroscopy is capable of providing specific spectral signature of various biomolecules present in the cells and tissues under various pathological conditions. The aim of this work is to develop a non-linear multi-class statistical methodology for discrimination of normal, neoplastic and malignant cells/tissues. The tissues were classified as normal, pre-malignant and malignant by employing Principal Component Analysis followed by Artificial Neural Network (PC-ANN). The overall accuracy achieved was 99%. Further, to get an insight into the quantitative biochemical composition of the normal, neoplastic and malignant tissues, a linear combination of the major biochemicals by non-negative least squares technique was fit to the measured Raman spectra of the tissues. This technique confirms the changes in the major biomolecules such as lipids, nucleic acids, actin, glycogen and collagen associated with the different pathological conditions. To study the efficacy of this technique in comparison with histopathology, we have utilized Principal Component followed by Linear Discriminant Analysis (PC-LDA) to discriminate the well differentiated, moderately differentiated and poorly differentiated squamous cell carcinoma with an accuracy of 94.0%. And the results demonstrated that Raman spectroscopy has the potential to complement the good old technique of histopathology.

Problems faced and coping strategies used by adolescents with mentally ill parents in Delhi.

PubMed

George, Shoba; Shaiju, Bindu; Sharma, Veena

2012-01-01

The present study was conducted to assess the problems faced by adolescents whose parents suffer from major mental illness at selected mental health institutes of Delhi. The objectives also included assessment of the coping strategies of the adolescents in dealing with these problems. The Stuart Stress Adaptation Model of Psychiatric Nursing Care was used as the conceptual framework. A descriptive survey approach with cross-sectional design was used in the study. A structured interview schedule was prepared. Purposive non-probability sampling technique was employed to interview 50 adolescents whose parents suffer from major mental illness. Data gathered was analysed and interpreted using both descriptive and inferential statistics. The study showed that majority of the adolescents had moderate problems as a result of their parent's mental illness. Area-wise analysis of the problems revealed that the highest problems faced were in family relationship and support and majority of the adolescents used maladaptive coping strategies. A set of guidelines on effective coping strategies was disseminated to these adolescents.

Multishaker modal testing

NASA Technical Reports Server (NTRS)

Craig, R. R., Jr.

1985-01-01

A component mode synthesis method for damped structures was developed and modal test methods were explored which could be employed to determine the relevant parameters required by the component mode synthesis method. Research was conducted on the following topics: (1) Development of a generalized time-domain component mode synthesis technique for damped systems; (2) Development of a frequency-domain component mode synthesis method for damped systems; and (3) Development of a system identification algorithm applicable to general damped systems. Abstracts are presented of the major publications which have been previously issued on these topics.

Basic Strategies of Dynamic Supportive Therapy

PubMed Central

Misch, Donald A.

2000-01-01

Supportive therapy is the psychotherapeutic approach employed with the majority of mentally ill individuals. Nevertheless, most mental health professional training programs dedicate little time and effort to the teaching and learning of supportive therapy, and many mental health professionals are unable to clearly and concisely articulate the nature or process of supportive work. Although supportive therapy incorporates many specific techniques from a wide variety of psychotherapy schools, it can be conceptualized as consisting of a more limited number of underlying strategies. The fundamental strategies that underpin effective supportive therapy with mentally ill individuals are described. PMID:11069130

"Mindless Medicals".

PubMed

Michell, Karen Elizabeth; Rispel, Laetitia C

2017-03-01

This article explores stakeholders' perceptions of the quality of occupational health service (OHS) delivery in South Africa. Using a purposive sampling technique, 11 focus group discussions (FGDs) were conducted in three provinces. Focus group participants ( n = 69) were recruited through professional organizations of occupational physicians and occupational health nurses as well as employer representatives of major industries in South Africa. Transcriptions of FGDs were analyzed using thematic content analysis. South Africa has diverse models of OHS delivery with varying quality. Focus group participants criticized the outsourced model of service delivery and the excessive focus on physical examinations to achieve legal compliance. These problems are exacerbated by a perceived lack of employer emphasis on occupational health, insufficient human and financial resources, and lack of specific quality of care standards for occupational health. Improvement in the quality of OHS delivery is essential to realize South Africa's quest for universal health coverage.

Aerospace Energy Systems Laboratory - Requirements and design approach

NASA Technical Reports Server (NTRS)

Glover, Richard D.

1988-01-01

The NASA Ames/Dryden Flight Research Facility operates a mixed fleet of research aircraft employing NiCd batteries in a variety of flight-critical applications. Dryden's Battery Systems Laboratory (BSL), a computerized facility for battery maintenance servicing, has evolved over two decades into one of the most advanced facilities of its kind in the world. Recently a major BSL upgrade was initiated with the goal of modernization to provide flexibility in meeting the needs of future advanced projects. The new facility will be called the Aerospace Energy Systems Laboratory (AESL) and will employ distributed processing linked to a centralized data base. AESL will be both a multistation servicing facility and a research laboratory for the advancement of energy storage system maintenance techniques. This paper describes the baseline requirements for the AESL and the design approach being taken for its mechanization.

Preferred Materials and Methods Employed for Endodontic Treatment by Iranian General Practitioners

PubMed Central

Raoof, Maryam; Zeini, Negar; Haghani, Jahangir; Sadr, Saeedeh; Mohammadalizadeh, Sakineh

2015-01-01

Introduction: The aim of this study was to gather information on the materials and methods employed in root canal treatment (RCT) by general dental practitioners (GDPs) in Iran. Methods and Materials: A questionnaire was distributed among 450 dentists who attended the 53th Iranian Dental Association congress. Participants were asked to consider demographic variables and answer the questions regarding the materials and methods commonly used in RCT. Descriptive statistics were given as absolute frequencies and valid percentages. The chi-square test was used to investigate the influence of gender and the years of professional activity for the employed materials and techniques. Results: The response rate was 84.88%. The results showed that 61.5% of the participants did not perform pulp sensitivity tests prior to RCT. Less than half of the general dental practitioners (47.4%) said that they would trace a sinus tract before starting the treatment. Nearly 16% of practitioners preferred the rubber dam isolation method. Over 36% of the practitioners reported using formocresol for pulpotomy. The combined approach of working length (WL) radiographs and electronic apex locators was used by 35.2% of the practitioners. Most of the respondents used K-file hand instruments for canal preparation and the technique of choice was step-back (43.5%), while 40.1% of respondents used NiTi rotary files, mostly ProTaper and RaCe. The most widely used irrigant was normal saline (61.8%). Calcium hydroxide was the most commonly used inter appointment medicament (84.6%). The most popular obturation technique was cold lateral condensation (81.7%) with 51% using zinc oxide-eugenol-based sealers. Conclusions: The majority of Iranian GDPs who participated in the present survey do not comply with quality guidelines of endodontic treatment. PMID:25834595

Microengineering of Metals and Ceramics: Part II: Special Replication Techniques, Automation and Properties; Volume 4: Advanced Micro & Nanosystems

NASA Astrophysics Data System (ADS)

Baltes, Henry; Brand, Oliver; Fedder, Gary K.; Hierold, Christofer; Korvink, Jan G.; Tabata, Osamu; Löhe, Detlef; Haußelt, Jürgen

2005-10-01

Microstructures, electronics, nanotechnology - these vast fields of research are growing together as the size gap narrows and many different materials are combined. Current research, engineering sucesses and newly commercialized products hint at the immense innovative potentials and future applications that open up once mankind controls shape and function from the atomic level right up to the visible world without any gaps. Continuing from the previous volume, authors from three major competence centres for microengineering here cover all aspects of specialized replication techniques and how to employ state-of-the-art technologies for testing and characterizing micro-scale components, and illustrate quality control aspects and strategies for automation of production procedures in view of future industrial production and commercialisation.

ENDOR-Induced EPR of Disordered Systems: Application to X-Irradiated Alanine.

PubMed

Kusakovskij, Jevgenij; Maes, Kwinten; Callens, Freddy; Vrielinck, Henk

2018-02-15

The electron paramagnetic resonance (EPR) spectra of radiation-induced radicals in organic solids are generally composed of multiple components that largely overlap due to their similar weak g anisotropy and a large number of hyperfine (HF) interactions. Such properties make these systems difficult to study using standard cw EPR spectroscopy even in single crystals. Electron-nuclear double-resonance (ENDOR) spectroscopy is a powerful and widely used complementary technique. In particular, ENDOR-induced EPR (EIE) experiments are useful for separating the overlapping contributions. In the present work, these techniques were employed to study the EPR spectrum of stable radicals in X-irradiated alanine, which is widely used in dosimetric applications. The principal values of all major proton HF interactions of the dominant radicals were determined by analyzing the magnetic field dependence of the ENDOR spectrum at 50 K, where the rotation of methyl groups is frozen. Accurate simulations of the EPR spectrum were performed after the major components were separated using an EIE analysis. As a result, new evidence in favor of the model of the second dominant radical was obtained.

Wavelet Analysis of SAR Images for Coastal Monitoring

NASA Technical Reports Server (NTRS)

Liu, Antony K.; Wu, Sunny Y.; Tseng, William Y.; Pichel, William G.

1998-01-01

The mapping of mesoscale ocean features in the coastal zone is a major potential application for satellite data. The evolution of mesoscale features such as oil slicks, fronts, eddies, and ice edge can be tracked by the wavelet analysis using satellite data from repeating paths. The wavelet transform has been applied to satellite images, such as those from Synthetic Aperture Radar (SAR), Advanced Very High-Resolution Radiometer (AVHRR), and ocean color sensor for feature extraction. In this paper, algorithms and techniques for automated detection and tracking of mesoscale features from satellite SAR imagery employing wavelet analysis have been developed. Case studies on two major coastal oil spills have been investigated using wavelet analysis for tracking along the coast of Uruguay (February 1997), and near Point Barrow, Alaska (November 1997). Comparison of SAR images with SeaWiFS (Sea-viewing Wide Field-of-view Sensor) data for coccolithophore bloom in the East Bering Sea during the fall of 1997 shows a good match on bloom boundary. This paper demonstrates that this technique is a useful and promising tool for monitoring of coastal waters.

Millimeter-wave imaging of magnetic fusion plasmas: technology innovations advancing physics understanding

NASA Astrophysics Data System (ADS)

Wang, Y.; Tobias, B.; Chang, Y.-T.; Yu, J.-H.; Li, M.; Hu, F.; Chen, M.; Mamidanna, M.; Phan, T.; Pham, A.-V.; Gu, J.; Liu, X.; Zhu, Y.; Domier, C. W.; Shi, L.; Valeo, E.; Kramer, G. J.; Kuwahara, D.; Nagayama, Y.; Mase, A.; Luhmann, N. C., Jr.

2017-07-01

Electron cyclotron emission (ECE) imaging is a passive radiometric technique that measures electron temperature fluctuations; and microwave imaging reflectometry (MIR) is an active radar imaging technique that measures electron density fluctuations. Microwave imaging diagnostic instruments employing these techniques have made important contributions to fusion science and have been adopted at major fusion facilities worldwide including DIII-D, EAST, ASDEX Upgrade, HL-2A, KSTAR, LHD, and J-TEXT. In this paper, we describe the development status of three major technological advancements: custom mm-wave integrated circuits (ICs), digital beamforming (DBF), and synthetic diagnostic modeling (SDM). These have the potential to greatly advance microwave fusion plasma imaging, enabling compact and low-noise transceiver systems with real-time, fast tracking ability to address critical fusion physics issues, including ELM suppression and disruptions in the ITER baseline scenario, naturally ELM-free states such as QH-mode, and energetic particle confinement (i.e. Alfvén eigenmode stability) in high-performance regimes that include steady-state and advanced tokamak scenarios. Furthermore, these systems are fully compatible with today’s most challenging non-inductive heating and current drive systems and capable of operating in harsh environments, making them the ideal approach for diagnosing long-pulse and steady-state tokamaks.

Millimeter-wave imaging of magnetic fusion plasmas: technology innovations advancing physics understanding

DOE PAGES

Wang, Y.; Tobias, B.; Chang, Y. -T.; ...

2017-03-14

Electron cyclotron emission (ECE) imaging is a passive radiometric technique that measures electron temperature fluctuations; and microwave imaging reflectometry (MIR) is an active radar imaging technique that measures electron density fluctuations. The microwave imaging diagnostic instruments employing these techniques have made important contributions to fusion science and have been adopted at major fusion facilities worldwide including DIII-D, EAST, ASDEX Upgrade, HL-2A, KSTAR, LHD, and J-TEXT. In this paper, we describe the development status of three major technological advancements: custom mm-wave integrated circuits (ICs), digital beamforming (DBF), and synthetic diagnostic modeling (SDM). These also have the potential to greatly advance microwavemore » fusion plasma imaging, enabling compact and low-noise transceiver systems with real-time, fast tracking ability to address critical fusion physics issues, including ELM suppression and disruptions in the ITER baseline scenario, naturally ELM-free states such as QH-mode, and energetic particle confinement (i.e. Alfven eigenmode stability) in high-performance regimes that include steady-state and advanced tokamak scenarios. Furthermore, these systems are fully compatible with today's most challenging non-inductive heating and current drive systems and capable of operating in harsh environments, making them the ideal approach for diagnosing long-pulse and steady-state tokamaks.« less

Analytical toxicology.

PubMed

Flanagan, R J; Widdop, B; Ramsey, J D; Loveland, M

1988-09-01

1. Major advances in analytical toxicology followed the introduction of spectroscopic and chromatographic techniques in the 1940s and early 1950s and thin layer chromatography remains important together with some spectrophotometric and other tests. However, gas- and high performance-liquid chromatography together with a variety of immunoassay techniques are now widely used. 2. The scope and complexity of forensic and clinical toxicology continues to increase, although the compounds for which emergency analyses are needed to guide therapy are few. Exclusion of the presence of hypnotic drugs can be important in suspected 'brain death' cases. 3. Screening for drugs of abuse has assumed greater importance not only for the management of the habituated patient, but also in 'pre-employment' and 'employment' screening. The detection of illicit drug administration in sport is also an area of increasing importance. 4. In industrial toxicology, the range of compounds for which blood or urine measurements (so called 'biological monitoring') can indicate the degree of exposure is increasing. The monitoring of environmental contaminants (lead, chlorinated pesticides) in biological samples has also proved valuable. 5. In the near future a consensus as to the units of measurement to be used is urgently required and more emphasis will be placed on interpretation, especially as regards possible behavioural effects of drugs or other poisons. Despite many advances in analytical techniques there remains a need for reliable, simple tests to detect poisons for use in smaller hospital and other laboratories.

Multiple variable motivators involved in the recruitment of physicians for the Indian Health Service.

PubMed

Hostetter, C L; Felsen, J D

1975-01-01

Attracting physicians to serve in isolated areas, often with marginal facilities, support staff, and remuneration, has long been a problem of the Indian Health Service (IHS). Until recently the physician draft was instrumental in motivating physicians to accept such assignments. Realizing that this "negative incentive" would no longer operate when the draft ended as of July 1, 1973, in the fall of 1972 the IHS staff launched some major "positive" efforts to recruit physicians. The mass media and other communication techniques were used to try to sell U.S. physicians and medical students on what the Service could offer them in terms of adventure, challenge, personal fulfillment, idealism, and the opportunity to be part of a progressive, comprehensive health system. Such efforts assisted in recruiting 69 physicians to begin service in July 1973. These 69 were in addition to approximately 100 who had already been recruited from among persons who had expressed interest in joining the Indian Health Service or who had applied to it before inception of this major recruitment effort. As of July 1, 1973, however, the Service was still approximately 30 physicians short of filling 200 vacancies. In June and July of 1973, an evaluation was done to determine what had motivated the 169 physicians to join the Indian Health Service. They were asked an open ended question: What prompted you to seek employment with the Indian Health Service? Whether physicians listed personal, subjective motivators or recruitment techniques was of as much interest as the specific answers they gave. More than 75 percent (100 of 129) mentioned recruitment techniques, such as magazine advertisements, rather than personal motivating factors, such as challenge. Personal contact with a present or former IHS physician seemed to be especially influential in attracting physicians. The present state of the recruitment art does not provide the means to adequately identify, qualify, quantify, and rank the multiple motivators that prompt physicians to join a program such as that of the Indian Health Service; nor does it allow for meaningful, predetermined identification of a limited pool of physicians who would have a high probability of joining such a program. At present, the best recruitment strategy appears to be to saturate the entire physician "marketplace" stressing with a variety of techniques the positive aspects of IHS employment. Physicians then select themselves for such employment by exhibiting a more than casual interest in the Indian Health Service.

A structural study of bone changes in knee osteoarthritis by synchrotron-based X-ray fluorescence and X-ray absorption spectroscopy techniques

NASA Astrophysics Data System (ADS)

Sindhupakorn, Bura; Thienpratharn, Suwittaya; Kidkhunthod, Pinit

2017-10-01

Osteoarthritis (OA) is characterized by degeneration of articular cartilage and thickening of subchondral bone. The present study investigated the changing of biochemical components of cartilage and bone compared between normal and OA people. Using Synchrotron-based X-ray fluorescence (SR-XRF) and X-ray absorption spectroscopy (XAS) techniquesincluding X-ray absorption near edge structure (XANES) and extended X-ray absorption fine structure (EXAFS) were employed for the bone changes in kneeosteoarthritisstudies. The bone samples were collected from various osteoarthritis patients with both male and female in the ages range between 20 and 74 years old. SR-XRF results excited at 4240 eV for Ca elements show a majority three main groups, based on their XRF intensities, 20-36 years, 40-60 years and over 70 years, respectively. By employing XAS techniques, XANES features can be used to clearly explain in term of electronic transitions occurring in bone samples which are affected from osteoarthritis symptoms. Moreover, a structural change around Ca ions in bone samples is obviously obtained by EXAFS results indicating an increase of Ca-amorphous phase when the ages increase.

In vivo tomographic imaging of deep seated cancer using fluorescence lifetime contrast

PubMed Central

Rice, William L.; Shcherbakova, Daria M; Verkusha, Vladislav V.; Kumar, Anand T.N.

2015-01-01

Preclinical cancer research would benefit from non-invasive imaging methods that allow tracking and visualization of early stage metastasis in vivo. While fluorescent proteins revolutionized intravital microscopy, two major challenges which still remain are tissue autofluorescence and hemoglobin absorption, which act to limit intravital optical techniques to large or subcutaneous tumors. Here we employ time-domain technology for the effective separation of tissue autofluorescence from extrinsic fluorophores, based on their distinct fluorescence lifetimes. Additionally, we employ cancer cells labelled with near infra-red fluorescent proteins (iRFP) to allow deep-tissue imaging. Our results demonstrate that time-domain imaging allows the detection of metastasis in deep-seated organs of living mice with a more than 20-fold increase in sensitivity compared to conventional continuous wave techniques. Furthermore, the distinct fluorescence lifetimes of each iRFP enables lifetime multiplexing of three different tumors, each expressing unique iRFP labels in the same animal. Fluorescence tomographic reconstructions reveal 3D distributions of iRFP720-expressing cancer cells in lungs and brain of live mice, allowing ready longitudinal monitoring of cancer cell fate with greater sensitivity than otherwise currently possible. PMID:25670171

An improved error assessment for the GEM-T1 gravitational model

NASA Technical Reports Server (NTRS)

Lerch, F. J.; Marsh, J. G.; Klosko, S. M.; Pavlis, E. C.; Patel, G. B.; Chinn, D. S.; Wagner, C. A.

1988-01-01

Several tests were designed to determine the correct error variances for the Goddard Earth Model (GEM)-T1 gravitational solution which was derived exclusively from satellite tracking data. The basic method employs both wholly independent and dependent subset data solutions and produces a full field coefficient estimate of the model uncertainties. The GEM-T1 errors were further analyzed using a method based upon eigenvalue-eigenvector analysis which calibrates the entire covariance matrix. Dependent satellite and independent altimetric and surface gravity data sets, as well as independent satellite deep resonance information, confirm essentially the same error assessment. These calibrations (utilizing each of the major data subsets within the solution) yield very stable calibration factors which vary by approximately 10 percent over the range of tests employed. Measurements of gravity anomalies obtained from altimetry were also used directly as observations to show that GEM-T1 is calibrated. The mathematical representation of the covariance error in the presence of unmodeled systematic error effects in the data is analyzed and an optimum weighting technique is developed for these conditions. This technique yields an internal self-calibration of the error model, a process which GEM-T1 is shown to approximate.

Energy Harvesting Hybrid Acoustic-Optical Underwater Wireless Sensor Networks Localization.

PubMed

Saeed, Nasir; Celik, Abdulkadir; Al-Naffouri, Tareq Y; Alouini, Mohamed-Slim

2017-12-26

Underwater wireless technologies demand to transmit at higher data rate for ocean exploration. Currently, large coverage is achieved by acoustic sensor networks with low data rate, high cost, high latency, high power consumption, and negative impact on marine mammals. Meanwhile, optical communication for underwater networks has the advantage of the higher data rate albeit for limited communication distances. Moreover, energy consumption is another major problem for underwater sensor networks, due to limited battery power and difficulty in replacing or recharging the battery of a sensor node. The ultimate solution to this problem is to add energy harvesting capability to the acoustic-optical sensor nodes. Localization of underwater sensor networks is of utmost importance because the data collected from underwater sensor nodes is useful only if the location of the nodes is known. Therefore, a novel localization technique for energy harvesting hybrid acoustic-optical underwater wireless sensor networks (AO-UWSNs) is proposed. AO-UWSN employs optical communication for higher data rate at a short transmission distance and employs acoustic communication for low data rate and long transmission distance. A hybrid received signal strength (RSS) based localization technique is proposed to localize the nodes in AO-UWSNs. The proposed technique combines the noisy RSS based measurements from acoustic communication and optical communication and estimates the final locations of acoustic-optical sensor nodes. A weighted multiple observations paradigm is proposed for hybrid estimated distances to suppress the noisy observations and give more importance to the accurate observations. Furthermore, the closed form solution for Cramer-Rao lower bound (CRLB) is derived for localization accuracy of the proposed technique.

Energy Harvesting Hybrid Acoustic-Optical Underwater Wireless Sensor Networks Localization

PubMed Central

Saeed, Nasir; Celik, Abdulkadir; Al-Naffouri, Tareq Y.; Alouini, Mohamed-Slim

2017-01-01

Underwater wireless technologies demand to transmit at higher data rate for ocean exploration. Currently, large coverage is achieved by acoustic sensor networks with low data rate, high cost, high latency, high power consumption, and negative impact on marine mammals. Meanwhile, optical communication for underwater networks has the advantage of the higher data rate albeit for limited communication distances. Moreover, energy consumption is another major problem for underwater sensor networks, due to limited battery power and difficulty in replacing or recharging the battery of a sensor node. The ultimate solution to this problem is to add energy harvesting capability to the acoustic-optical sensor nodes. Localization of underwater sensor networks is of utmost importance because the data collected from underwater sensor nodes is useful only if the location of the nodes is known. Therefore, a novel localization technique for energy harvesting hybrid acoustic-optical underwater wireless sensor networks (AO-UWSNs) is proposed. AO-UWSN employs optical communication for higher data rate at a short transmission distance and employs acoustic communication for low data rate and long transmission distance. A hybrid received signal strength (RSS) based localization technique is proposed to localize the nodes in AO-UWSNs. The proposed technique combines the noisy RSS based measurements from acoustic communication and optical communication and estimates the final locations of acoustic-optical sensor nodes. A weighted multiple observations paradigm is proposed for hybrid estimated distances to suppress the noisy observations and give more importance to the accurate observations. Furthermore, the closed form solution for Cramer-Rao lower bound (CRLB) is derived for localization accuracy of the proposed technique. PMID:29278405

An advanced approach for computer modeling and prototyping of the human tooth.

PubMed

Chang, Kuang-Hua; Magdum, Sheetalkumar; Khera, Satish C; Goel, Vijay K

2003-05-01

This paper presents a systematic and practical method for constructing accurate computer and physical models that can be employed for the study of human tooth mechanics. The proposed method starts with a histological section preparation of a human tooth. Through tracing outlines of the tooth on the sections, discrete points are obtained and are employed to construct B-spline curves that represent the exterior contours and dentino-enamel junction (DEJ) of the tooth using a least square curve fitting technique. The surface skinning technique is then employed to quilt the B-spline curves to create a smooth boundary and DEJ of the tooth using B-spline surfaces. These surfaces are respectively imported into SolidWorks via its application protocol interface to create solid models. The solid models are then imported into Pro/MECHANICA Structure for finite element analysis (FEA). The major advantage of the proposed method is that it first generates smooth solid models, instead of finite element models in discretized form. As a result, a more advanced p-FEA can be employed for structural analysis, which usually provides superior results to traditional h-FEA. In addition, the solid model constructed is smooth and can be fabricated with various scales using the solid freeform fabrication technology. This method is especially useful in supporting bioengineering applications, where the shape of the object is usually complicated. A human maxillary second molar is presented to illustrate and demonstrate the proposed method. Note that both the solid and p-FEA models of the molar are presented. However, comparison between p- and h-FEA models is out of the scope of the paper.

Analysis of explicit model predictive control for path-following control

PubMed Central

2018-01-01

In this paper, explicit Model Predictive Control(MPC) is employed for automated lane-keeping systems. MPC has been regarded as the key to handle such constrained systems. However, the massive computational complexity of MPC, which employs online optimization, has been a major drawback that limits the range of its target application to relatively small and/or slow problems. Explicit MPC can reduce this computational burden using a multi-parametric quadratic programming technique(mp-QP). The control objective is to derive an optimal front steering wheel angle at each sampling time so that autonomous vehicles travel along desired paths, including straight, circular, and clothoid parts, at high entry speeds. In terms of the design of the proposed controller, a method of choosing weighting matrices in an optimization problem and the range of horizons for path-following control are described through simulations. For the verification of the proposed controller, simulation results obtained using other control methods such as MPC, Linear-Quadratic Regulator(LQR), and driver model are employed, and CarSim, which reflects the features of a vehicle more realistically than MATLAB/Simulink, is used for reliable demonstration. PMID:29534080

Analysis of explicit model predictive control for path-following control.

PubMed

Lee, Junho; Chang, Hyuk-Jun

2018-01-01

In this paper, explicit Model Predictive Control(MPC) is employed for automated lane-keeping systems. MPC has been regarded as the key to handle such constrained systems. However, the massive computational complexity of MPC, which employs online optimization, has been a major drawback that limits the range of its target application to relatively small and/or slow problems. Explicit MPC can reduce this computational burden using a multi-parametric quadratic programming technique(mp-QP). The control objective is to derive an optimal front steering wheel angle at each sampling time so that autonomous vehicles travel along desired paths, including straight, circular, and clothoid parts, at high entry speeds. In terms of the design of the proposed controller, a method of choosing weighting matrices in an optimization problem and the range of horizons for path-following control are described through simulations. For the verification of the proposed controller, simulation results obtained using other control methods such as MPC, Linear-Quadratic Regulator(LQR), and driver model are employed, and CarSim, which reflects the features of a vehicle more realistically than MATLAB/Simulink, is used for reliable demonstration.

Off-the-job training for VATS employing anatomically correct lung models.

PubMed

Obuchi, Toshiro; Imakiire, Takayuki; Miyahara, Sou; Nakashima, Hiroyasu; Hamanaka, Wakako; Yanagisawa, Jun; Hamatake, Daisuke; Shiraishi, Takeshi; Moriyama, Shigeharu; Iwasaki, Akinori

2012-02-01

We evaluated our simulated major lung resection employing anatomically correct lung models as "off-the-job training" for video-assisted thoracic surgery trainees. A total of 76 surgeons voluntarily participated in our study. They performed video-assisted thoracic surgical lobectomy employing anatomically correct lung models, which are made of sponges so that vessels and bronchi can be cut using usual surgical techniques with typical forceps. After the simulation surgery, participants answered questionnaires on a visual analogue scale, in terms of their level of interest and the reality of our training method as off-the-job training for trainees. We considered that the closer a score was to 10, the more useful our method would be for training new surgeons. Regarding the appeal or level of interest in this simulation surgery, the mean score was 8.3 of 10, and regarding reality, it was 7.0. The participants could feel some of the real sensations of the surgery and seemed to be satisfied to perform the simulation lobectomy. Our training method is considered to be suitable as an appropriate type of surgical off-the-job training.

The 'robustness' of vocabulary intervention in the public schools: targets and techniques employed in speech-language therapy.

PubMed

Justice, Laura M; Schmitt, Mary Beth; Murphy, Kimberly A; Pratt, Amy; Biancone, Tricia

2014-01-01

This study examined vocabulary intervention-in terms of targets and techniques-for children with language impairment receiving speech-language therapy in public schools (i.e., non-fee-paying schools) in the United States. Vocabulary treatments and targets were examined with respect to their alignment with the empirically validated practice of rich vocabulary intervention. Participants were forty-eight 5-7-year-old children participating in kindergarten or the first-grade year of school, all of whom had vocabulary-specific goals on their individualized education programmes. Two therapy sessions per child were coded to determine what vocabulary words were being directly targeted and what techniques were used for each. Study findings showed that the majority of words directly targeted during therapy were lower-level basic vocabulary words (87%) and very few (1%) were academically relevant. On average, three techniques were used per word to promote deep understanding. Interpreting findings against empirical descriptions of rich vocabulary intervention indicates that children were exposed to some but not all aspects of this empirically supported practice. © 2013 Royal College of Speech and Language Therapists.

Application of an integrated multi-criteria decision making AHP-TOPSIS methodology for ETL software selection.

PubMed

Hanine, Mohamed; Boutkhoum, Omar; Tikniouine, Abdessadek; Agouti, Tarik

2016-01-01

Actually, a set of ETL software (Extract, Transform and Load) is available to constitute a major investment market. Each ETL uses its own techniques for extracting, transforming and loading data into data warehouse, which makes the task of evaluating ETL software very difficult. However, choosing the right software of ETL is critical to the success or failure of any Business Intelligence project. As there are many impacting factors in the selection of ETL software, the same process is considered as a complex multi-criteria decision making (MCDM) problem. In this study, an application of decision-making methodology that employs the two well-known MCDM techniques, namely Analytic Hierarchy Process (AHP) and Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) methods is designed. In this respect, the aim of using AHP is to analyze the structure of the ETL software selection problem and obtain weights of the selected criteria. Then, TOPSIS technique is used to calculate the alternatives' ratings. An example is given to illustrate the proposed methodology. Finally, a software prototype for demonstrating both methods is implemented.

Creative user-centered visualization design for energy analysts and modelers.

PubMed

Goodwin, Sarah; Dykes, Jason; Jones, Sara; Dillingham, Iain; Dove, Graham; Duffy, Alison; Kachkaev, Alexander; Slingsby, Aidan; Wood, Jo

2013-12-01

We enhance a user-centered design process with techniques that deliberately promote creativity to identify opportunities for the visualization of data generated by a major energy supplier. Visualization prototypes developed in this way prove effective in a situation whereby data sets are largely unknown and requirements open - enabling successful exploration of possibilities for visualization in Smart Home data analysis. The process gives rise to novel designs and design metaphors including data sculpting. It suggests: that the deliberate use of creativity techniques with data stakeholders is likely to contribute to successful, novel and effective solutions; that being explicit about creativity may contribute to designers developing creative solutions; that using creativity techniques early in the design process may result in a creative approach persisting throughout the process. The work constitutes the first systematic visualization design for a data rich source that will be increasingly important to energy suppliers and consumers as Smart Meter technology is widely deployed. It is novel in explicitly employing creativity techniques at the requirements stage of visualization design and development, paving the way for further use and study of creativity methods in visualization design.

Aerospace energy systems laboratory: Requirements and design approach

NASA Technical Reports Server (NTRS)

Glover, Richard D.

1988-01-01

The NASA Ames-Dryden Flight Research Facility at Edwards, California, operates a mixed fleet of research aircraft employing nickel-cadmium (NiCd) batteries in a variety of flight-critical applications. Dryden's Battery Systems Laboratory (BSL), a computerized facility for battery maintenance servicing, has developed over two decades into one of the most advanced facilities of its kind in the world. Recently a major BSL upgrade was initiated with the goal of modernization to provide flexibility in meeting the needs of future advanced projects. The new facility will be called the Aerospace Energy Systems Laboratory (AESL) and will employ distributed processing linked to a centralized data base. AESL will be both a multistation servicing facility and a research laboratory for the advancement of energy storage system maintenance techniques. This paper describes the baseline requirements for the AESL and the design approach being taken for its mechanization.

Brachytherapy devices and methods employing americium-241

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gray, L. A.

1985-04-16

Sources and methods for radiation therapy, particularly brachytherapy, employing americium-241 (60 keV gamma emission and 433 year half-life) provide major advantages for radiotherapy, including simplified radiation protection, dose reduction to healthy tissue, increased dose to tumor, and improved dose distributions. A number of apparent drawbacks and unfavorable considerations including low gamma factor, high self-absorption, increased activity required and alpha-particle generation leading to helium gas pressure buildup and potential neutron contamination in the generated radiation are all effectively dealt with and overcome through recognition of subtle favorable factors unique to americium-241 among brachytherapy sources and through suitable constructional techniques. Due tomore » an additional amount of radiation, in the order of 50%, provided primarily to nearby regions as a result of Compton scatter in tissue and water, higher dose rates occur than would be predicted by conventional calculations.« less

Free Mesh Method: fundamental conception, algorithms and accuracy study

PubMed Central

YAGAWA, Genki

2011-01-01

The finite element method (FEM) has been commonly employed in a variety of fields as a computer simulation method to solve such problems as solid, fluid, electro-magnetic phenomena and so on. However, creation of a quality mesh for the problem domain is a prerequisite when using FEM, which becomes a major part of the cost of a simulation. It is natural that the concept of meshless method has evolved. The free mesh method (FMM) is among the typical meshless methods intended for particle-like finite element analysis of problems that are difficult to handle using global mesh generation, especially on parallel processors. FMM is an efficient node-based finite element method that employs a local mesh generation technique and a node-by-node algorithm for the finite element calculations. In this paper, FMM and its variation are reviewed focusing on their fundamental conception, algorithms and accuracy. PMID:21558752

Development of the first infrared satellite observatory

NASA Technical Reports Server (NTRS)

Smith, G. M.; Squibb, G. F.

1984-01-01

A development history is given for the Infrared Astronomical Satelite (IRAS), whose primary mission objective is an unbiased, all-sky survey in the 8-120 micron wavelength range. A point source catalog of more than 200,000 IR sources, to be published later this year, represents the accomplishment of this objective. IRAS has also conducted 10,000 pointed observations of specific objects. Attention is given to the cost increases and schedule slips which resulted from the substantial technical challenges of IRAS hardware and software development, and to the management techniques which had to be employed in this major international project.

New frontiers in ground-based optical astronomy

NASA Astrophysics Data System (ADS)

Strom, Steve

1991-07-01

Technological advances made in telescope designs during 1980's are outlined, including a segmented primary mirror for a 10-m telescope, new mirror-figuring techniques, and control systems based on computers and electronics. A new detector technology employing CCD's and advances in high-resolution telescopes are considered, along with such areas of research ready for major advances given new observing tools as the origin of large-scale structures in the universe, the creation and evolution of galaxies, and the formation of stars and planetary systems. Attention is focused on circumstellar disks, dust veils, jets, and brown dwarfs.

DIY: "Do Imaging Yourself" - Conventional microscopes as powerful tools for in vivo investigation.

PubMed

Antunes, Maísa Mota; Carvalho, Érika de; Menezes, Gustavo Batista

2018-01-01

Intravital imaging has been increasingly employed in cell biology studies and it is becoming one of the most powerful tools for in vivo investigation. Although some protocols can be extremely complex, most intravital imaging procedures can be performed using basic surgery and animal maintenance techniques. More importantly, regular confocal microscopes - the same that are used for imaging immunofluorescence slides - can also acquire high quality intravital images and movies after minor adaptations. Here we propose minimal adaptations in stock microscopes that allow major improvements in different fields of scientific investigation. Copyright © 2017 Elsevier Ltd. All rights reserved.

Fabrication of composite propfan blades for a cruise missile wind tunnel model

NASA Technical Reports Server (NTRS)

Fite, E. Brian

1993-01-01

This report outlines the procedures that were employed in fabricating prototype graphite-epoxy composite prop fan blades. These blades were used in wind tunnel tests that investigated prop fan propulsion system interactions with a missile airframe in order to study the feasibility of an advanced-technology-propfan-propelled missile. Major phases of the blade fabrication presented include machining of the master blade, mold fabrication, ply cutting and assembly, blade curing, and quality assurance. Specifically, four separate designs were fabricated, 18 blades of each geometry, using the same fabrication technique for each design.

Current progress in patient-specific modeling

PubMed Central

2010-01-01

We present a survey of recent advancements in the emerging field of patient-specific modeling (PSM). Researchers in this field are currently simulating a wide variety of tissue and organ dynamics to address challenges in various clinical domains. The majority of this research employs three-dimensional, image-based modeling techniques. Recent PSM publications mostly represent feasibility or preliminary validation studies on modeling technologies, and these systems will require further clinical validation and usability testing before they can become a standard of care. We anticipate that with further testing and research, PSM-derived technologies will eventually become valuable, versatile clinical tools. PMID:19955236

Transcatheter arterial embolization--major complications and their prevention.

PubMed

Miller, F J; Mineau, D E

1983-01-01

A thorough account is given of the complications of embolization techniques in nonneurovascular areas, including hepatic infarction, renal and splenic abscess formation. Infarction of the urinary bladder, gallbladder, stomach, and bowel are discussed. Suggestions are offered to prevent complications from embolization where possible. Specific agents for embolization are detailed and their relative merits are compared; ethyl alcohol has recently gained popularity for treating esophageal varices and infarcting renal tumors. Care is advocated when using alcohol in the renal arteries; employing this agent is currently contraindicated in the celiac and mesenteric arteries. Coils and balloon systems are also described along with their potential complications.

Chemical and Biological Mobile Laboratory: infrastructure employed by Brazilian Army in emergency response actions

NASA Astrophysics Data System (ADS)

Cardozo, M.; Oliveira, V. G. M.; Sousa, R. B.; de Paula, R. L.

2018-03-01

The Brazilian Army specified and acquired a mobile chemical and biological laboratory in order to confirm in a fast and mobile way with more precise analytical techniques the information obtained by the emergency responders field teams. The laboratory was designed for displacement in different scenarios of the national territory. This paper describes the laboratorial structure, the material flow and the deployment of this defense product in the major international events occurred in Brazil from 2011 to 2016, with the objective of providing in situ identification of chemical and biological threats.

Real-time dual-comb spectroscopy with a free-running bidirectionally mode-locked fiber laser

NASA Astrophysics Data System (ADS)

Mehravar, S.; Norwood, R. A.; Peyghambarian, N.; Kieu, K.

2016-06-01

Dual-comb technique has enabled exciting applications in high resolution spectroscopy, precision distance measurements, and 3D imaging. Major advantages over traditional methods can be achieved with dual-comb technique. For example, dual-comb spectroscopy provides orders of magnitude improvement in acquisition speed over standard Fourier-transform spectroscopy while still preserving the high resolution capability. Wider adoption of the technique has, however, been hindered by the need for complex and expensive ultrafast laser systems. Here, we present a simple and robust dual-comb system that employs a free-running bidirectionally mode-locked fiber laser operating at telecommunication wavelength. Two femtosecond frequency combs (with a small difference in repetition rates) are generated from a single laser cavity to ensure mutual coherent properties and common noise cancellation. As the result, we have achieved real-time absorption spectroscopy measurements without the need for complex servo locking with accurate frequency referencing, and relatively high signal-to-noise ratio.

Over production of lignocellulosic enzymes of Coriolus versicolor by genetic engineering methodology. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, A.L.

1998-07-01

The project seeks to understand the biological and chemical processes involved in the secretion of the enzyme polyphenol oxidase (PPO) by the hyphae, the basic unit of the filamentous fungus Coriolus versicolor. These studies are made to determine rational strategies for enhanced secretion of PPO, both with the use of recombinant DNA techniques and without. This effort focuses on recombinant DNA techniques to enhance enzyme production. The major thrust of this project was two-fold: to mass produce C. versicolor tyrosinase (polyphenol oxidase) by genetic engineering as well as cultural manipulations; and to utilize PPO as a biocatalyst in the processingmore » of lignocellulose as a renewable energy resource. In this study, the assessment of genomic and cDNA recombinant clones with regards to the overproduction of PPO continued. Further, immunocytochemical techniques were employed to assess the mechanism(s) involved in the secretion of PPO by the hyphae. Also, factors influencing PPO secretion were examined.« less

Federal and State Employment Laws. Module Number 11. Work Experience Program Modules. Coordination Techniques Series.

ERIC Educational Resources Information Center

Kidney, John

This self-instructional module, the eleventh in a series of 16 on techniques for coordinating work experience programs, deals with federal and state employment laws. Addressed in the module are federal and state employment laws pertaining to minimum wage for student learners, minimum wage for full-time students, unemployment insurance, child labor…

An Evaluation of GuttaFlow2 in Filling Artificial Internal Resorption Cavities: An in vitro Study.

PubMed

Mohammad, Yara; Alafif, Hisham; Hajeer, Mohammad; Yassin, Oula

2016-06-01

Obturation of root canal with internal resorption represents a major challenge in Endodontics. In spite of that, usual obturation techniques are often employed without considering the best technique to solve this problem. The goal of this study was to investigate the ability of GuttaFlow2 in filling artificial internal resorption cavities. The study sample included 36 human upper central incisors that were prepared using Protaper system (F4). Internal resorption cavities were prepared by cutting each tooth at 7 mm from the apex and preparing hemispherical cavities on both the sides and then re-attaching them. The sample was randomly separated into three groups (n = 12 in each group). In the first group, thermal injection technique (Obtura II) was employed and served as the control group. In the second group, injection of cold free-flow obturation technique with a master cone (GF2-C) was employed, whereas in the third group injection of cold free-flow obturation without a master cone (GF2) was followed. The teeth were re-cut at the same level as before and examined under a stereomicroscope. Subsequently, the captured images were transferred to AutoCAD program to measure the percentage of total filling "TF," gutta-percha "G," sealer "S," and voids "V" out of the total surface of the cross sections. All materials showed high filling properties in terms of "total filling," ranging from 99.17% (for Obtura II) to 99.72% (for GF2-C). Regarding gutta-percha percentages of filling, they ranged from 83.15 to 83.93%, whereas those for the sealer ranged from 5.71 to 15.24%. GuttaFlow2 group with a master cone appeared to give the best results despite the insignificant differences among the three groups. The GuttaFlow2 with a master cone technique seemed to be a promising filling material and gave results similar to those observed with Obtura II. It is recommended for use to obturate internal resorption cavities in clinical practice due to its good adaptability to root canal walls, ease of handling, and application. Internal resorption defects can be successfully filled with GuttaFlow2 material when supplemented with a master cone, and the results are comparable with those obtained with the Obtura II technique.

Effects of Structural Change on Labor Supply in Wisconsin.

ERIC Educational Resources Information Center

Gyan-Baffour, George; Shaffer, Ron

A survey of 501 Wisconsin firms (260 responses) assessed the impact of changes in demand, productivity, and technology on the employment needs and training requirements of Wisconsin employers in 10 selected economic sectors. Major findings included the following: (1) Wisconsin's services sector has recently experienced major employment growth and…

Cartilage defect repair in horses: Current strategies and recent developments in regenerative medicine of the equine joint with emphasis on the surgical approach.

PubMed

Cokelaere, Stefan; Malda, Jos; van Weeren, René

2016-08-01

Chondral and osteochondral lesions due to injury or other pathology are highly prevalent conditions in horses (and humans) and commonly result in the development of osteoarthritis and progression of joint deterioration. Regenerative medicine of articular cartilage is an emerging clinical treatment option for patients with articular cartilage injury or disease. Functional articular cartilage restoration, however, remains a major challenge, but the field is progressing rapidly and there is an increasing body of supportive clinical and scientific evidence. This review gives an overview of the established and emerging surgical techniques employed for cartilage repair in horses. Through a growing insight in surgical cartilage repair possibilities, surgeons might be more stimulated to explore novel techniques in a clinical setting. Copyright © 2016 Elsevier Ltd. All rights reserved.

Detection of Glaucoma Using Image Processing Techniques: A Critique.

PubMed

Kumar, B Naveen; Chauhan, R P; Dahiya, Nidhi

2018-01-01

The primary objective of this article is to present a summary of different types of image processing methods employed for the detection of glaucoma, a serious eye disease. Glaucoma affects the optic nerve in which retinal ganglion cells become dead, and this leads to loss of vision. The principal cause is the increase in intraocular pressure, which occurs in open-angle and angle-closure glaucoma, the two major types affecting the optic nerve. In the early stages of glaucoma, no perceptible symptoms appear. As the disease progresses, vision starts to become hazy, leading to blindness. Therefore, early detection of glaucoma is needed for prevention. Manual analysis of ophthalmic images is fairly time-consuming and accuracy depends on the expertise of the professionals. Automatic analysis of retinal images is an important tool. Automation aids in the detection, diagnosis, and prevention of risks associated with the disease. Fundus images obtained from a fundus camera have been used for the analysis. Requisite pre-processing techniques have been applied to the image and, depending upon the technique, various classifiers have been used to detect glaucoma. The techniques mentioned in the present review have certain advantages and disadvantages. Based on this study, one can determine which technique provides an optimum result.

Personalised 3D Printed Medicines: Which Techniques and Polymers Are More Successful?

PubMed

Konta, Andrea Alice; García-Piña, Marta; Serrano, Dolores R

2017-09-22

The interindividual variability is an increasingly global problem when treating patients from different backgrounds with diverse customs, metabolism, and necessities. Dose adjustment is frequently based on empirical methods, and therefore, the chance of undesirable side effects to occur is high. Three-dimensional (3D) Printed medicines are revolutionsing the pharmaceutical market as potential tools to achieve personalised treatments adapted to the specific requirements of each patient, taking into account their age, weight, comorbidities, pharmacogenetic, and pharmacokinetic characteristics. Additive manufacturing or 3D printing consists of a wide range of techniques classified in many categories but only three of them are mostly used in the 3D printing of medicines: printing-based inkjet systems, nozzle-based deposition systems, and laser-based writing systems. There are several drawbacks when using each technique and also the type of polymers readily available do not always possess the optimal properties for every drug. The aim of this review is to give an overview about the current techniques employed in 3D printing medicines, highlighting their advantages, disadvantages, along with the polymer and drug requirements for a successful printing. The major application of these techniques will be also discussed.

Trace elemental analysis of Indian natural moonstone gems by PIXE and XRD techniques.

PubMed

Venkateswara Rao, R; Venkateswarulu, P; Kasipathi, C; Sivajyothi, S

2013-12-01

A selected number of Indian Eastern Ghats natural moonstone gems were studied with a powerful nuclear analytical and non-destructive Proton Induced X-ray Emission (PIXE) technique. Thirteen elements, including V, Co, Ni, Zn, Ga, Ba and Pb, were identified in these moonstones and may be useful in interpreting the various geochemical conditions and the probable cause of their inceptions in the moonstone gemstone matrix. Furthermore, preliminary XRD studies of different moonstone patterns were performed. The PIXE technique is a powerful method for quickly determining the elemental concentration of a substance. A 3MeV proton beam was employed to excite the samples. The chemical constituents of moonstones from parts of the Eastern Ghats geological formations of Andhra Pradesh, India were determined, and gemological studies were performed on those gems. The crystal structure and the lattice parameters of the moonstones were estimated using X-Ray Diffraction studies, trace and minor elements were determined using the PIXE technique, and major compositional elements were confirmed by XRD. In the present work, the usefulness and versatility of the PIXE technique for research in geo-scientific methodology is established. © 2013 Elsevier Ltd. All rights reserved.

Personalised 3D Printed Medicines: Which Techniques and Polymers Are More Successful?

PubMed Central

Konta, Andrea Alice; García-Piña, Marta

2017-01-01

The interindividual variability is an increasingly global problem when treating patients from different backgrounds with diverse customs, metabolism, and necessities. Dose adjustment is frequently based on empirical methods, and therefore, the chance of undesirable side effects to occur is high. Three-dimensional (3D) Printed medicines are revolutionsing the pharmaceutical market as potential tools to achieve personalised treatments adapted to the specific requirements of each patient, taking into account their age, weight, comorbidities, pharmacogenetic, and pharmacokinetic characteristics. Additive manufacturing or 3D printing consists of a wide range of techniques classified in many categories but only three of them are mostly used in the 3D printing of medicines: printing-based inkjet systems, nozzle-based deposition systems, and laser-based writing systems. There are several drawbacks when using each technique and also the type of polymers readily available do not always possess the optimal properties for every drug. The aim of this review is to give an overview about the current techniques employed in 3D printing medicines, highlighting their advantages, disadvantages, along with the polymer and drug requirements for a successful printing. The major application of these techniques will be also discussed. PMID:28952558

Assessing the Effectiveness of Statistical Classification Techniques in Predicting Future Employment of Participants in the Temporary Assistance for Needy Families Program

ERIC Educational Resources Information Center

Montoya, Isaac D.

2008-01-01

Three classification techniques (Chi-square Automatic Interaction Detection [CHAID], Classification and Regression Tree [CART], and discriminant analysis) were tested to determine their accuracy in predicting Temporary Assistance for Needy Families program recipients' future employment. Technique evaluation was based on proportion of correctly…

Verification Techniques for Parameter Selection and Bayesian Model Calibration Presented for an HIV Model

NASA Astrophysics Data System (ADS)

Wentworth, Mami Tonoe

Uncertainty quantification plays an important role when making predictive estimates of model responses. In this context, uncertainty quantification is defined as quantifying and reducing uncertainties, and the objective is to quantify uncertainties in parameter, model and measurements, and propagate the uncertainties through the model, so that one can make a predictive estimate with quantified uncertainties. Two of the aspects of uncertainty quantification that must be performed prior to propagating uncertainties are model calibration and parameter selection. There are several efficient techniques for these processes; however, the accuracy of these methods are often not verified. This is the motivation for our work, and in this dissertation, we present and illustrate verification frameworks for model calibration and parameter selection in the context of biological and physical models. First, HIV models, developed and improved by [2, 3, 8], describe the viral infection dynamics of an HIV disease. These are also used to make predictive estimates of viral loads and T-cell counts and to construct an optimal control for drug therapy. Estimating input parameters is an essential step prior to uncertainty quantification. However, not all the parameters are identifiable, implying that they cannot be uniquely determined by the observations. These unidentifiable parameters can be partially removed by performing parameter selection, a process in which parameters that have minimal impacts on the model response are determined. We provide verification techniques for Bayesian model calibration and parameter selection for an HIV model. As an example of a physical model, we employ a heat model with experimental measurements presented in [10]. A steady-state heat model represents a prototypical behavior for heat conduction and diffusion process involved in a thermal-hydraulic model, which is a part of nuclear reactor models. We employ this simple heat model to illustrate verification techniques for model calibration. For Bayesian model calibration, we employ adaptive Metropolis algorithms to construct densities for input parameters in the heat model and the HIV model. To quantify the uncertainty in the parameters, we employ two MCMC algorithms: Delayed Rejection Adaptive Metropolis (DRAM) [33] and Differential Evolution Adaptive Metropolis (DREAM) [66, 68]. The densities obtained using these methods are compared to those obtained through the direct numerical evaluation of the Bayes' formula. We also combine uncertainties in input parameters and measurement errors to construct predictive estimates for a model response. A significant emphasis is on the development and illustration of techniques to verify the accuracy of sampling-based Metropolis algorithms. We verify the accuracy of DRAM and DREAM by comparing chains, densities and correlations obtained using DRAM, DREAM and the direct evaluation of Bayes formula. We also perform similar analysis for credible and prediction intervals for responses. Once the parameters are estimated, we employ energy statistics test [63, 64] to compare the densities obtained by different methods for the HIV model. The energy statistics are used to test the equality of distributions. We also consider parameter selection and verification techniques for models having one or more parameters that are noninfluential in the sense that they minimally impact model outputs. We illustrate these techniques for a dynamic HIV model but note that the parameter selection and verification framework is applicable to a wide range of biological and physical models. To accommodate the nonlinear input to output relations, which are typical for such models, we focus on global sensitivity analysis techniques, including those based on partial correlations, Sobol indices based on second-order model representations, and Morris indices, as well as a parameter selection technique based on standard errors. A significant objective is to provide verification strategies to assess the accuracy of those techniques, which we illustrate in the context of the HIV model. Finally, we examine active subspace methods as an alternative to parameter subset selection techniques. The objective of active subspace methods is to determine the subspace of inputs that most strongly affect the model response, and to reduce the dimension of the input space. The major difference between active subspace methods and parameter selection techniques is that parameter selection identifies influential parameters whereas subspace selection identifies a linear combination of parameters that impacts the model responses significantly. We employ active subspace methods discussed in [22] for the HIV model and present a verification that the active subspace successfully reduces the input dimensions.

Gender abuse and major depression among transgender women: a prospective study of vulnerability and resilience.

PubMed

Nuttbrock, Larry; Bockting, Walter; Rosenblum, Andrew; Hwahng, Sel; Mason, Mona; Macri, Monica; Becker, Jeffrey

2014-11-01

We examined the social and interpersonal context of gender abuse and its effects on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition major depression among transgender women. We conducted a 3-year prospective study (2004-2007) among 230 transgender women aged 19 to 59 years from the New York City Metropolitan Area. Statistical techniques included generalized estimating equations (logistic regression). We observed significant associations of psychological and physical gender abuse with major depression during follow-up. New or persistent experiences of both types of abuse were associated with 4- to 7-fold increases in the likelihood of incident major depression. Employment, transgender presentation, sex work, and hormone therapy correlated across time with psychological abuse; the latter 2 variables correlated with physical abuse. The association of psychological abuse with depression was stronger among younger than among older transgender women. Psychological and physical gender abuse is endemic in this population and may result from occupational success and attempts to affirm gender identity. Both types of abuse have serious mental health consequences in the form of major depression. Older transgender women have apparently developed some degree of resilience to psychological gender abuse.

Gender Abuse and Major Depression Among Transgender Women: A Prospective Study of Vulnerability and Resilience

PubMed Central

Bockting, Walter; Rosenblum, Andrew; Hwahng, Sel; Mason, Mona; Macri, Monica; Becker, Jeffrey

2014-01-01

Objectives. We examined the social and interpersonal context of gender abuse and its effects on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition major depression among transgender women. Methods. We conducted a 3-year prospective study (2004–2007) among 230 transgender women aged 19 to 59 years from the New York City Metropolitan Area. Statistical techniques included generalized estimating equations (logistic regression). Results. We observed significant associations of psychological and physical gender abuse with major depression during follow-up. New or persistent experiences of both types of abuse were associated with 4- to 7-fold increases in the likelihood of incident major depression. Employment, transgender presentation, sex work, and hormone therapy correlated across time with psychological abuse; the latter 2 variables correlated with physical abuse. The association of psychological abuse with depression was stronger among younger than among older transgender women. Conclusions. Psychological and physical gender abuse is endemic in this population and may result from occupational success and attempts to affirm gender identity. Both types of abuse have serious mental health consequences in the form of major depression. Older transgender women have apparently developed some degree of resilience to psychological gender abuse. PMID:24328655

Progress Towards a New Technique for Measuring Local Electric and Magnetic Field Fluctuations in High Temperature Plasmas

NASA Astrophysics Data System (ADS)

Burke, M. G.; Fonck, R. J.; McKee, G. R.; Winz, G. R.

2017-10-01

Local measurements of electrostatic and magnetic turbulence in fusion grade plasmas is a critical missing component in advancing our understanding of current experiments and validating nonlinear turbulence simulations. A novel diagnostic for measuring local electric and magnetic field fluctuations (Ẽ and B ) is being developed to address this need. It employs high-speed measurements of the spectral linewidth and/or line intensities of the Motional Stark Effect split neutral beam emission. This emission is split into several spectral components, with the amount of splitting being proportional to local magnetic and electric fields at the emission site. High spectral resolution ( 0.025 nm), high throughput ( 0.01 cm2str), and high speed (f 250 kHz) are required for the measurement of fast changes in the MSE spectrum. Spatial heterodyne spectroscopy (SHS) techniques coupled to a CMOS detector can meet these demands. A prototype SHS has been deployed to DIII-D for initial testing in the tokamak environment, SNR evaluation, and neutral beam efficacy. In addition, design studies of the SHS interferogram are ongoing to further optimize the measurement technique. One major contributor to loss of fringe contrast is line broadening arising from employing a large collection lens. This broadening can be mitigated by making the lens at the tokamak wall optically conjugate with the interference fringes image field. Work supported by US DOE Grant DE-FG02-89ER53296.

Designs for surge immunity in critical electronic facilities

NASA Technical Reports Server (NTRS)

Roberts, Edward F., Jr.

1991-01-01

In recent years, Federal Aviation Administration (FAA) embarked on a program replacing older tube type electronic equipment with newer solid state equipment. This replacement program dramatically increased the susceptibility of the FAA's facilities to lightning related damages. The proposal is presented of techniques which may be employed to lessen the susceptibility of new FAA electronic facility designs to failures resulting from lightning related surges and transients as well as direct strikes. The general concept espoused is one of a consistent system approach employing both perimeter and internal protection. It compares the technique presently employed to reduce electronic noise with other techniques which reduce noise while lowering susceptibility to lightning related damage. It is anticipated that these techniques will be employed in the design of an Air Traffic Control Tower in a high isokeraunic area. This facility would be subjected to rigorous monitoring over a multi-year period to provide quantitative data hopefully supporting the advantage of this design.

Automated design of genomic Southern blot probes

PubMed Central

2010-01-01

Background Sothern blotting is a DNA analysis technique that has found widespread application in molecular biology. It has been used for gene discovery and mapping and has diagnostic and forensic applications, including mutation detection in patient samples and DNA fingerprinting in criminal investigations. Southern blotting has been employed as the definitive method for detecting transgene integration, and successful homologous recombination in gene targeting experiments. The technique employs a labeled DNA probe to detect a specific DNA sequence in a complex DNA sample that has been separated by restriction-digest and gel electrophoresis. Critically for the technique to succeed the probe must be unique to the target locus so as not to cross-hybridize to other endogenous DNA within the sample. Investigators routinely employ a manual approach to probe design. A genome browser is used to extract DNA sequence from the locus of interest, which is searched against the target genome using a BLAST-like tool. Ideally a single perfect match is obtained to the target, with little cross-reactivity caused by homologous DNA sequence present in the genome and/or repetitive and low-complexity elements in the candidate probe. This is a labor intensive process often requiring several attempts to find a suitable probe for laboratory testing. Results We have written an informatic pipeline to automatically design genomic Sothern blot probes that specifically attempts to optimize the resultant probe, employing a brute-force strategy of generating many candidate probes of acceptable length in the user-specified design window, searching all against the target genome, then scoring and ranking the candidates by uniqueness and repetitive DNA element content. Using these in silico measures we can automatically design probes that we predict to perform as well, or better, than our previous manual designs, while considerably reducing design time. We went on to experimentally validate a number of these automated designs by Southern blotting. The majority of probes we tested performed well confirming our in silico prediction methodology and the general usefulness of the software for automated genomic Southern probe design. Conclusions Software and supplementary information are freely available at: http://www.genes2cognition.org/software/southern_blot PMID:20113467

Pedagogical Techniques Employed by the Television Show "MythBusters"

NASA Astrophysics Data System (ADS)

Zavrel, Erik

2016-11-01

"MythBusters," the long-running though recently discontinued Discovery Channel science entertainment television program, has proven itself to be far more than just a highly rated show. While its focus is on entertainment, the show employs an array of pedagogical techniques to communicate scientific concepts to its audience. These techniques include: achieving active learning, avoiding jargon, employing repetition to ensure comprehension, using captivating demonstrations, cultivating an enthusiastic disposition, and increasing intrinsic motivation to learn. In this content analysis, episodes from the show's 10-year history were examined for these techniques. "MythBusters" represents an untapped source of pedagogical techniques, which science educators may consider availing themselves of in their tireless effort to better reach their students. Physics educators in particular may look to "MythBusters" for inspiration and guidance in how to incorporate these techniques into their own teaching and help their students in the learning process.

Antenna analysis using neural networks

NASA Technical Reports Server (NTRS)

Smith, William T.

1992-01-01

Conventional computing schemes have long been used to analyze problems in electromagnetics (EM). The vast majority of EM applications require computationally intensive algorithms involving numerical integration and solutions to large systems of equations. The feasibility of using neural network computing algorithms for antenna analysis is investigated. The ultimate goal is to use a trained neural network algorithm to reduce the computational demands of existing reflector surface error compensation techniques. Neural networks are computational algorithms based on neurobiological systems. Neural nets consist of massively parallel interconnected nonlinear computational elements. They are often employed in pattern recognition and image processing problems. Recently, neural network analysis has been applied in the electromagnetics area for the design of frequency selective surfaces and beam forming networks. The backpropagation training algorithm was employed to simulate classical antenna array synthesis techniques. The Woodward-Lawson (W-L) and Dolph-Chebyshev (D-C) array pattern synthesis techniques were used to train the neural network. The inputs to the network were samples of the desired synthesis pattern. The outputs are the array element excitations required to synthesize the desired pattern. Once trained, the network is used to simulate the W-L or D-C techniques. Various sector patterns and cosecant-type patterns (27 total) generated using W-L synthesis were used to train the network. Desired pattern samples were then fed to the neural network. The outputs of the network were the simulated W-L excitations. A 20 element linear array was used. There were 41 input pattern samples with 40 output excitations (20 real parts, 20 imaginary). A comparison between the simulated and actual W-L techniques is shown for a triangular-shaped pattern. Dolph-Chebyshev is a different class of synthesis technique in that D-C is used for side lobe control as opposed to pattern shaping. The interesting thing about D-C synthesis is that the side lobes have the same amplitude. Five-element arrays were used. Again, 41 pattern samples were used for the input. Nine actual D-C patterns ranging from -10 dB to -30 dB side lobe levels were used to train the network. A comparison between simulated and actual D-C techniques for a pattern with -22 dB side lobe level is shown. The goal for this research was to evaluate the performance of neural network computing with antennas. Future applications will employ the backpropagation training algorithm to drastically reduce the computational complexity involved in performing EM compensation for surface errors in large space reflector antennas.

Antenna analysis using neural networks

NASA Astrophysics Data System (ADS)

Smith, William T.

1992-09-01

Conventional computing schemes have long been used to analyze problems in electromagnetics (EM). The vast majority of EM applications require computationally intensive algorithms involving numerical integration and solutions to large systems of equations. The feasibility of using neural network computing algorithms for antenna analysis is investigated. The ultimate goal is to use a trained neural network algorithm to reduce the computational demands of existing reflector surface error compensation techniques. Neural networks are computational algorithms based on neurobiological systems. Neural nets consist of massively parallel interconnected nonlinear computational elements. They are often employed in pattern recognition and image processing problems. Recently, neural network analysis has been applied in the electromagnetics area for the design of frequency selective surfaces and beam forming networks. The backpropagation training algorithm was employed to simulate classical antenna array synthesis techniques. The Woodward-Lawson (W-L) and Dolph-Chebyshev (D-C) array pattern synthesis techniques were used to train the neural network. The inputs to the network were samples of the desired synthesis pattern. The outputs are the array element excitations required to synthesize the desired pattern. Once trained, the network is used to simulate the W-L or D-C techniques. Various sector patterns and cosecant-type patterns (27 total) generated using W-L synthesis were used to train the network. Desired pattern samples were then fed to the neural network. The outputs of the network were the simulated W-L excitations. A 20 element linear array was used. There were 41 input pattern samples with 40 output excitations (20 real parts, 20 imaginary).

Exogenous Molecular Probes for Targeted Imaging in Cancer: Focus on Multi-modal Imaging

PubMed Central

Joshi, Bishnu P.; Wang, Thomas D.

2010-01-01

Cancer is one of the major causes of mortality and morbidity in our healthcare system. Molecular imaging is an emerging methodology for the early detection of cancer, guidance of therapy, and monitoring of response. The development of new instruments and exogenous molecular probes that can be labeled for multi-modality imaging is critical to this process. Today, molecular imaging is at a crossroad, and new targeted imaging agents are expected to broadly expand our ability to detect and manage cancer. This integrated imaging strategy will permit clinicians to not only localize lesions within the body but also to manage their therapy by visualizing the expression and activity of specific molecules. This information is expected to have a major impact on drug development and understanding of basic cancer biology. At this time, a number of molecular probes have been developed by conjugating various labels to affinity ligands for targeting in different imaging modalities. This review will describe the current status of exogenous molecular probes for optical, scintigraphic, MRI and ultrasound imaging platforms. Furthermore, we will also shed light on how these techniques can be used synergistically in multi-modal platforms and how these techniques are being employed in current research. PMID:22180839

Value-Addition for Empowerment and Employability through Intervention of ODL Mode of IGNOU

ERIC Educational Resources Information Center

Kishore, S.

2013-01-01

In the developing country like India, the output of graduates from higher educational institutions is high. But, the major concern is that majority of graduates are not employable, especially from rural areas for want of skills expected by the employer. The soft skills, communication skills and multidisciplinary knowledge are essential to become…

3D reconstruction of a carotid bifurcation from 2D transversal ultrasound images.

PubMed

Yeom, Eunseop; Nam, Kweon-Ho; Jin, Changzhu; Paeng, Dong-Guk; Lee, Sang-Joon

2014-12-01

Visualizing and analyzing the morphological structure of carotid bifurcations are important for understanding the etiology of carotid atherosclerosis, which is a major cause of stroke and transient ischemic attack. For delineation of vasculatures in the carotid artery, ultrasound examinations have been widely employed because of a noninvasive procedure without ionizing radiation. However, conventional 2D ultrasound imaging has technical limitations in observing the complicated 3D shapes and asymmetric vasodilation of bifurcations. This study aims to propose image-processing techniques for better 3D reconstruction of a carotid bifurcation in a rat by using 2D cross-sectional ultrasound images. A high-resolution ultrasound imaging system with a probe centered at 40MHz was employed to obtain 2D transversal images. The lumen boundaries in each transverse ultrasound image were detected by using three different techniques; an ellipse-fitting, a correlation mapping to visualize the decorrelation of blood flow, and the ellipse-fitting on the correlation map. When the results are compared, the third technique provides relatively good boundary extraction. The incomplete boundaries of arterial lumen caused by acoustic artifacts are somewhat resolved by adopting the correlation mapping and the distortion in the boundary detection near the bifurcation apex was largely reduced by using the ellipse-fitting technique. The 3D lumen geometry of a carotid artery was obtained by volumetric rendering of several 2D slices. For the 3D vasodilatation of the carotid bifurcation, lumen geometries at the contraction and expansion states were simultaneously depicted at various view angles. The present 3D reconstruction methods would be useful for efficient extraction and construction of the 3D lumen geometries of carotid bifurcations from 2D ultrasound images. Copyright © 2014 Elsevier B.V. All rights reserved.

Teachers of the Alexander Technique in the UK and the people who take their lessons: A national cross-sectional survey.

PubMed

Eldred, J; Hopton, A; Donnison, E; Woodman, J; MacPherson, H

2015-06-01

Given the rising profile of the Alexander Technique in the UK, there is a need for a comprehensive description of its teachers and of those who currently take lessons. In a national survey of Alexander teachers, we set out to address this information gap. A cross-sectional survey of 871 UK members of three main Alexander Technique teachers' professional associations was conducted. A questionnaire requested information about their professional background, teaching practice and methods, and about the people who attend lessons and their reasons for seeking help. With an overall response rate of 61%, 534 teachers responded; 74% were female with median age of 58 years, 60% had a higher education qualification, and 95% were self-employed, many with additional non-Alexander paid employment. The majority (87%) offered lessons on their own premises or in a privately rented room, and 19% provided home visits; both individual and group lessons were provided. People who took lessons were predominantly female (66%) with a median age of 48 years, and 91% paid for their lessons privately. Nearly two-thirds (62%) began lessons for reasons related to musculoskeletal conditions, including back symptoms, posture, neck pain, and shoulder pain. Other reasons were general (18%, including well-being), performance-related (10%, including voice-, music-, and sport-related), psychological (5%) and neurological (3%). We estimate that Alexander teachers in the UK provide approximately 400,000 lessons per year. This study provides an overview of Alexander Technique teaching in the UK today and data that may be useful when planning future research. Copyright © 2015 Elsevier Ltd. All rights reserved.

Global Design Optimization for Aerodynamics and Rocket Propulsion Components

NASA Technical Reports Server (NTRS)

Shyy, Wei; Papila, Nilay; Vaidyanathan, Rajkumar; Tucker, Kevin; Turner, James E. (Technical Monitor)

2000-01-01

Modern computational and experimental tools for aerodynamics and propulsion applications have matured to a stage where they can provide substantial insight into engineering processes involving fluid flows, and can be fruitfully utilized to help improve the design of practical devices. In particular, rapid and continuous development in aerospace engineering demands that new design concepts be regularly proposed to meet goals for increased performance, robustness and safety while concurrently decreasing cost. To date, the majority of the effort in design optimization of fluid dynamics has relied on gradient-based search algorithms. Global optimization methods can utilize the information collected from various sources and by different tools. These methods offer multi-criterion optimization, handle the existence of multiple design points and trade-offs via insight into the entire design space, can easily perform tasks in parallel, and are often effective in filtering the noise intrinsic to numerical and experimental data. However, a successful application of the global optimization method needs to address issues related to data requirements with an increase in the number of design variables, and methods for predicting the model performance. In this article, we review recent progress made in establishing suitable global optimization techniques employing neural network and polynomial-based response surface methodologies. Issues addressed include techniques for construction of the response surface, design of experiment techniques for supplying information in an economical manner, optimization procedures and multi-level techniques, and assessment of relative performance between polynomials and neural networks. Examples drawn from wing aerodynamics, turbulent diffuser flows, gas-gas injectors, and supersonic turbines are employed to help demonstrate the issues involved in an engineering design context. Both the usefulness of the existing knowledge to aid current design practices and the need for future research are identified.

Patient similarity for precision medicine: a systematic review.

PubMed

Parimbelli, E; Marini, S; Sacchi, L; Bellazzi, R

2018-06-01

Evidence-based medicine is the most prevalent paradigm adopted by physicians. Clinical practice guidelines typically define a set of recommendations together with eligibility criteria that restrict their applicability to a specific group of patients. The ever-growing size and availability of health-related data is currently challenging the broad definitions of guideline-defined patient groups. Precision medicine leverages on genetic, phenotypic, or psychosocial characteristics to provide precise identification of patient subsets for treatment targeting. Defining a patient similarity measure is thus an essential step to allow stratification of patients into clinically-meaningful subgroups. The present review investigates the use of patient similarity as a tool to enable precision medicine. 279 articles were analyzed along four dimensions: data types considered, clinical domains of application, data analysis methods, and translational stage of findings. Cancer-related research employing molecular profiling and standard data analysis techniques such as clustering constitute the majority of the retrieved studies. Chronic and psychiatric diseases follow as the second most represented clinical domains. Interestingly, almost one quarter of the studies analyzed presented a novel methodology, with the most advanced employing data integration strategies and being portable to different clinical domains. Integration of such techniques into decision support systems constitutes and interesting trend for future research. Copyright © 2018. Published by Elsevier Inc.

Semantic segmentation of mFISH images using convolutional networks.

PubMed

Pardo, Esteban; Morgado, José Mário T; Malpica, Norberto

2018-04-30

Multicolor in situ hybridization (mFISH) is a karyotyping technique used to detect major chromosomal alterations using fluorescent probes and imaging techniques. Manual interpretation of mFISH images is a time consuming step that can be automated using machine learning; in previous works, pixel or patch wise classification was employed, overlooking spatial information which can help identify chromosomes. In this work, we propose a fully convolutional semantic segmentation network for the interpretation of mFISH images, which uses both spatial and spectral information to classify each pixel in an end-to-end fashion. The semantic segmentation network developed was tested on samples extracted from a public dataset using cross validation. Despite having no labeling information of the image it was tested on, our algorithm yielded an average correct classification ratio (CCR) of 87.41%. Previously, this level of accuracy was only achieved with state of the art algorithms when classifying pixels from the same image in which the classifier has been trained. These results provide evidence that fully convolutional semantic segmentation networks may be employed in the computer aided diagnosis of genetic diseases with improved performance over the current image analysis methods. © 2018 International Society for Advancement of Cytometry. © 2018 International Society for Advancement of Cytometry.

Testing the Relationship of Gender and Business Major to Professional Development Behaviors and Expected Employment

ERIC Educational Resources Information Center

Blau, Gary; Hill, Theodore L.; Snell, Corinne; Atwater, Craig; Halbert, Terry; Zuckerman, M. Michael

2016-01-01

This study's results, with 664 surveyed graduating business students, demonstrated that creating four groups, using gender and quantitative or nonquantitative major, was useful for testing their relationships to professional development behaviors and expected employment. Results showed that male-nonquantitative majors (n = 144) reported the lowest…

Satellite laser ranging as a tool for the recovery of tropospheric gradients

NASA Astrophysics Data System (ADS)

Drożdżewski, M.; Sośnica, K.

2018-11-01

Space geodetic techniques, such as Global Navigation Satellite Systems (GNSS) and Very Long Baseline Interferometry (VLBI) have been extensively used for the recovery of the tropospheric parameters. Both techniques employ microwave observations, for which the troposphere is a non-dispersive medium and which are very sensitive to the water vapor content. Satellite laser ranging (SLR) is the only space geodetic technique used for the definition of the terrestrial reference frames which employs optical - laser observations. The SLR sensitivity to the hydrostatic part of the troposphere delay is similar to that of microwave observations, whereas the sensitivity of laser observations to non-hydrostatic part of the delay is about two orders of magnitude smaller than in the case of microwave observations. Troposphere is a dispersive medium for optical wavelengths, which means that the SLR tropospheric delay depends on the laser wavelength. This paper presents the sensitivity and capability of the SLR observations for the recovery of azimuthal asymmetry over the SLR stations, which can be described as horizontal gradients of the troposphere delay. For the first time, the horizontal gradients are estimated, together with other parameters typically estimated from the SLR observations to spherical LAGEOS satellites, i.e., station coordinates, earth rotation parameters, and satellite orbits. Most of the SLR stations are co-located with GNSS receivers, thus, a cross-correlation between both techniques is possible. We compare our SLR horizontal gradients to GNSS results and to the horizontal gradients derived from the numerical weather models (NWM). Due to a small number of the SLR observations, SLR is not capable of reconstructing short-period phenomena occurring in the atmosphere. However, the long-term analysis allows for the recovery of the atmosphere asymmetry using SLR. As a result, the mean offsets of the SLR-derived horizontal gradients agree to the level of 47%, 74%, 54% with GNSS, hydrostatic delay, and total delay from NWM, respectively. SLR can be thus employed as a tool for the recovery of the atmospheric parameters with a major sensitivity to the hydrostatic part of the delay.

Portal vein territory identification using indocyanine green fluorescence imaging: Technical details and short-term outcomes.

PubMed

Kobayashi, Yuta; Kawaguchi, Yoshikuni; Kobayashi, Kosuke; Mori, Kazuhiro; Arita, Junichi; Sakamoto, Yoshihiro; Hasegawa, Kiyoshi; Kokudo, Norihiro

2017-12-01

Portal vein (PV) territory identification during liver resection may be performed using indocyanine green (ICG) fluorescence imaging technique. However, the technical details of the fluorescence staining technique have not been fully elucidated. This study was performed to demonstrate the technical details of PV territory identification using fluorescence imaging and evaluates the short-term outcomes. From 2011 to 2015, 105 underwent liver resection at the University of Tokyo Hospital with one of the following fluorescence staining techniques by transhepatic PV injection or intravenous injection of ICG: single staining (n = 36), multiple staining (n = 31), counterstaining (n = 22), negative staining (n = 13), or paradoxical negative staining (n = 3). The PV territory was identified as a region with fluorescence or a defect of fluorescence using one of the five staining techniques. ICG was administered by transhepatic PV injection in all but the negative staining technique, which employed intravenous injection. No adverse events associated with the ICG administration occurred. The mortality, postoperative total morbidity, and the major complication (Clavien-Dindo grade ≥III) rates were 0.0%, 14.3%, and 7.6%. We have demonstrated the technical details of five types of fluorescence staining techniques. These techniques are safe to perform and facilitate clear visualization of the PV territory in real time, enhancing the efficacy of anatomical removal of such territories. © 2017 Wiley Periodicals, Inc.

Experimentally induced innovations lead to persistent culture via conformity in wild birds

PubMed Central

Aplin, L.M.; Farine, D.R.; Morand-Ferron, J.; Cockburn, A.; Thornton, A.; Sheldon, B.C.

2014-01-01

In human societies, cultural norms arise when behaviours are transmitted with high-fidelity social learning through social networks1. However a paucity of experimental studies has meant that there is no comparable understanding of the process by which socially transmitted behaviours may spread and persist in animal populations2,3. Here, we introduce alternative novel foraging techniques into replicated wild sub-populations of great tits (Parus major), and employ automated tracking to map the diffusion, establishment and long-term persistence of seeded behaviours. We further use social network analysis to examine social factors influencing diffusion dynamics. From just two trained birds in each sub-population, information spread rapidly through social network ties to reach an average of 75% of individuals, with 508 knowledgeable individuals performing 58,975 solutions. Sub-populations were heavily biased towards the technique originally introduced, resulting in established local arbitrary traditions that were stable over two generations, despite high population turnover. Finally, we demonstrate a strong effect of social conformity, with individuals disproportionately adopting the most frequent local variant when first learning, but then also continuing to favour social over personal information by matching their technique to the majority variant. Cultural conformity is thought to be a key factor in the evolution of complex culture in humans4-7. In providing the first experimental demonstration of conformity in a wild non-primate, and of cultural norms in foraging techniques in any wild animal, our results suggest a much wider evolutionary occurrence of such apparently complex cultural behaviour. PMID:25470065

Remote detection of mental workload changes using cardiac parameters assessed with a low-cost webcam.

PubMed

Bousefsaf, Frédéric; Maaoui, Choubeila; Pruski, Alain

2014-10-01

We introduce a new framework for detecting mental workload changes using video frames obtained from a low-cost webcam. Image processing in addition to a continuous wavelet transform filtering method were developed and applied to remove major artifacts and trends on raw webcam photoplethysmographic signals. The measurements are performed on human faces. To induce stress, we have employed a computerized and interactive Stroop color word test on a set composed by twelve participants. The electrodermal activity of the participants was recorded and compared to the mental workload curve assessed by merging two parameters derived from the pulse rate variability and photoplethysmographic amplitude fluctuations, which reflect peripheral vasoconstriction changes. The results exhibit strong correlation between the two measurement techniques. This study offers further support for the applicability of mental workload detection by remote and low-cost means, providing an alternative to conventional contact techniques. Copyright © 2014 Elsevier Ltd. All rights reserved.

Light water reactor lower head failure analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rempe, J.L.; Chavez, S.A.; Thinnes, G.L.

1993-10-01

This document presents the results from a US Nuclear Regulatory Commission-sponsored research program to investigate the mode and timing of vessel lower head failure. Major objectives of the analysis were to identify plausible failure mechanisms and to develop a method for determining which failure mode would occur first in different light water reactor designs and accident conditions. Failure mechanisms, such as tube ejection, tube rupture, global vessel failure, and localized vessel creep rupture, were studied. Newly developed models and existing models were applied to predict which failure mechanism would occur first in various severe accident scenarios. So that a broadermore » range of conditions could be considered simultaneously, calculations relied heavily on models with closed-form or simplified numerical solution techniques. Finite element techniques-were employed for analytical model verification and examining more detailed phenomena. High-temperature creep and tensile data were obtained for predicting vessel and penetration structural response.« less

Resolving the percentage of component terrains within single resolution elements

NASA Technical Reports Server (NTRS)

Marsh, S. E.; Switzer, P.; Kowalik, W. S.; Lyon, R. J. P.

1980-01-01

An approximate maximum likelihood technique employing a widely available discriminant analysis program is discussed that has been developed for resolving the percentage of component terrains within single resolution elements. The method uses all four channels of Landsat data simultaneously and does not require prior knowledge of the percentage of components in mixed pixels. It was tested in five cases that were chosen to represent mixtures of outcrop, soil and vegetation which would typically be encountered in geologic studies with Landsat data. For all five cases, the method proved to be superior to single band weighted average and linear regression techniques and permitted an estimate of the total area occupied by component terrains to within plus or minus 6% of the true area covered. Its major drawback is a consistent overestimation of the pixel component percent of the darker materials (vegetation) and an underestimation of the pixel component percent of the brighter materials (sand).

Protein and starch digestibilities and mineral availability of products developed from potato, soy and corn flour.

PubMed

Gahlawat, P; Sehgal, S

1998-01-01

A technique for development of potato flour was standardized. Five products viz. cake, biscuit, weaning food, panjiri and ladoo were prepared incorporating potato flour, defatted soy flour and corn flour. Baking and roasting were the major processing techniques employed for the development of these products. Protein, ash and fat contents of potato flour were almost similar to those of raw potatoes. Significant differences in protein, ash and fat contents of all the products were observed. Protein and starch digestibility of potato flour was significantly higher than that of raw potatoes. Protein digestibility increased by 12 to 17 percent on baking or roasting of products. Processed products had significantly higher starch digestibility and mineral availability compared to raw products. Thus, it can be concluded that roasting and baking are effective means of improving starch and protein digestibility and mineral availability of products.

Bio-Inspired Networking — Self-Organizing Networked Embedded Systems

NASA Astrophysics Data System (ADS)

Dressler, Falko

The turn to nature has brought us many unforeseen great concepts and solutions. This course seems to hold on for many research domains. In this article, we study the applicability of biological mechanisms and techniques in the domain of communications. In particular, we study the behavior and the challenges in networked embedded systems that are meant to self-organize in large groups of nodes. Application examples include wireless sensor networks and sensor/actuator networks. Based on a review of the needs and requirements in such networks, we study selected bio-inspired networking approaches that claim to outperform other methods in specific domains. We study mechanisms in swarm intelligence, the artificial immune system, and approaches based on investigations on the cellular signaling pathways. As a major conclusion, we derive that bio-inspired networking techniques do have advantages compared to engineering methods. Nevertheless, selection and employment must be done carefully to achieve the desired performance gains.

Balloon-borne photoionization mass spectrometer for measurement of stratospheric gases

NASA Technical Reports Server (NTRS)

Aikin, A. C.; Maier, E. J. R.

1978-01-01

A balloon-borne photoionization mass spectrometer used to measure stratospheric trace gases is described. Ions are created with photons from high-intensity krypton discharge lamps and a quadrupole mass analyzer is employed for ion identification. Differential pumping is achieved with liquid helium cryopumping. To insure measurement of unperturbed stratospheric air, the entire system is contained in a sealed gondola and the atmospheric sample is taken some distance away during descent. The photoionization technique allows the detection of a low ionization potential constituent, such as nitric oxide, at less than a part in one billion in the presence of the major atmospheric gases and their isotopes. Operation of the mass spectrometer system was demonstrated during a daytime flight from Palestine, Texas on 26 April 1977. The sensitivity achieved and the unique selectivity afforded by this technique offer a capability for trace constituent measurement not possible with the more conventional electron impact ionization approach.

Employment and Occupations in Europe in the 1980s. Effects of Technical and Economic Changes on the Employment Situation. Project No. 1 of the CCC: "Preparation for Life." Preparation for Working Life.

ERIC Educational Resources Information Center

Cacace, Nicole

This paper is an attempt to forecast for 1990 the following: (1) employment structures in the member countries of the Council of Europe for all three major sectors of the economy; and (2) employment structures in the Council of Europe for the nine major sectors of the manufacturing industry (food, textiles, leather and clothing, wood and…

Regular and singular pulse and front solutions and possible isochronous behavior in the short-pulse equation: Phase-plane, multi-infinite series and variational approaches

NASA Astrophysics Data System (ADS)

Gambino, G.; Tanriver, U.; Guha, P.; Choudhury, A. Ghose; Choudhury, S. Roy

2015-02-01

In this paper we employ three recent analytical approaches to investigate the possible classes of traveling wave solutions of some members of a family of so-called short-pulse equations (SPE). A recent, novel application of phase-plane analysis is first employed to show the existence of breaking kink wave solutions in certain parameter regimes. Secondly, smooth traveling waves are derived using a recent technique to derive convergent multi-infinite series solutions for the homoclinic (heteroclinic) orbits of the traveling-wave equations for the SPE equation, as well as for its generalized version with arbitrary coefficients. These correspond to pulse (kink or shock) solutions respectively of the original PDEs. We perform many numerical tests in different parameter regime to pinpoint real saddle equilibrium points of the corresponding traveling-wave equations, as well as ensure simultaneous convergence and continuity of the multi-infinite series solutions for the homoclinic/heteroclinic orbits anchored by these saddle points. Unlike the majority of unaccelerated convergent series, high accuracy is attained with relatively few terms. And finally, variational methods are employed to generate families of both regular and embedded solitary wave solutions for the SPE PDE. The technique for obtaining the embedded solitons incorporates several recent generalizations of the usual variational technique and it is thus topical in itself. One unusual feature of the solitary waves derived here is that we are able to obtain them in analytical form (within the assumed ansatz for the trial functions). Thus, a direct error analysis is performed, showing the accuracy of the resulting solitary waves. Given the importance of solitary wave solutions in wave dynamics and information propagation in nonlinear PDEs, as well as the fact that not much is known about solutions of the family of generalized SPE equations considered here, the results obtained are both new and timely.

High-pressure torsion for new hydrogen storage materials.

PubMed

Edalati, Kaveh; Akiba, Etsuo; Horita, Zenji

2018-01-01

High-pressure torsion (HPT) is widely used as a severe plastic deformation technique to create ultrafine-grained structures with promising mechanical and functional properties. Since 2007, the method has been employed to enhance the hydrogenation kinetics in different Mg-based hydrogen storage materials. Recent studies showed that the method is effective not only for increasing the hydrogenation kinetics but also for improving the hydrogenation activity, for enhancing the air resistivity and more importantly for synthesizing new nanostructured hydrogen storage materials with high densities of lattice defects. This manuscript reviews some major findings on the impact of HPT process on the hydrogen storage performance of different titanium-based and magnesium-based materials.

Fossil life on Mars

NASA Technical Reports Server (NTRS)

Walter, M. R.

1989-01-01

Three major problems beset paleontologists searching for morphological evidence of life on early Earth: selecting a prospective site; finding biogenic structures; and distinguishing biogenic from abiogenic structures. The same problems arise on Mars. Terrestrial experience suggests that, with the techniques that can be employed remotely, ancient springs, including hot springs, are more prospective than lake deposits. If, on the other hand, the search is for chemical evidence, the strategy can be very different, and lake deposits are attractive targets. Lakes and springs frequenly occur in close proximity, and therefore a strategy that combines the two would seem to maximize the chance of success. The strategy for a search for stromatolite on Mars is discussed.

A multiple hypotheses uncertainty analysis in hydrological modelling: about model structure, landscape parameterization, and numerical integration

NASA Astrophysics Data System (ADS)

Pilz, Tobias; Francke, Till; Bronstert, Axel

2016-04-01

Until today a large number of competing computer models has been developed to understand hydrological processes and to simulate and predict streamflow dynamics of rivers. This is primarily the result of a lack of a unified theory in catchment hydrology due to insufficient process understanding and uncertainties related to model development and application. Therefore, the goal of this study is to analyze the uncertainty structure of a process-based hydrological catchment model employing a multiple hypotheses approach. The study focuses on three major problems that have received only little attention in previous investigations. First, to estimate the impact of model structural uncertainty by employing several alternative representations for each simulated process. Second, explore the influence of landscape discretization and parameterization from multiple datasets and user decisions. Third, employ several numerical solvers for the integration of the governing ordinary differential equations to study the effect on simulation results. The generated ensemble of model hypotheses is then analyzed and the three sources of uncertainty compared against each other. To ensure consistency and comparability all model structures and numerical solvers are implemented within a single simulation environment. First results suggest that the selection of a sophisticated numerical solver for the differential equations positively affects simulation outcomes. However, already some simple and easy to implement explicit methods perform surprisingly well and need less computational efforts than more advanced but time consuming implicit techniques. There is general evidence that ambiguous and subjective user decisions form a major source of uncertainty and can greatly influence model development and application at all stages.

Statistical Aspects of the North Atlantic Basin Tropical Cyclones: Trends, Natural Variability, and Global Warming

NASA Technical Reports Server (NTRS)

Wilson, Robert M.

2007-01-01

Statistical aspects of the North Atlantic basin tropical cyclones for the interval 1945- 2005 are examined, including the variation of the yearly frequency of occurrence for various subgroups of storms (all tropical cyclones, hurricanes, major hurricanes, U.S. landfalling hurricanes, and category 4/5 hurricanes); the yearly variation of the mean latitude and longitude (genesis location) of all tropical cyclones and hurricanes; and the yearly variation of the mean peak wind speeds, lowest pressures, and durations for all tropical cyclones, hurricanes, and major hurricanes. Also examined is the relationship between inferred trends found in the North Atlantic basin tropical cyclonic activity and natural variability and global warming, the latter described using surface air temperatures from the Armagh Observatory Armagh, Northern Ireland. Lastly, a simple statistical technique is employed to ascertain the expected level of North Atlantic basin tropical cyclonic activity for the upcoming 2007 season.

Prolonged Exposure Therapy and Irritable Bowel Syndrome: A Case Study Examining the Impact of a Trauma-Focused Treatment on a Physical Condition

PubMed Central

Weaver, Terrí L.; Nishith, Pallavi; Resick, Patricia A.

2010-01-01

Previous research has shown that psychological treatments, particularly those employing cognitive techniques, are particularly effective in the treatment of irritable bowel syndrome (IBS). It is presumed that these psychological interventions are effective at ameliorating the IBS by treating an underlying psychological disorder (often an anxiety disorder), which may be contributing to the autonomic reactivity. This case study examined the change in the physical symptoms of IBS for a patient seeking treatment for rape-related PTSD with comorbid conditions of major depression and panic. At posttreatment, the patient no longer met criteria for PTSD, major depression, or panic. In addition, her primary symptom of IBS, diarrhea frequency, was significantly improved. These findings were maintained at 3 and 9 months posttreatment. Implications for the assessment and treatment of IBS patients with PTSD are discussed. PMID:21179387

Communication architecture for large geostationary platforms

NASA Technical Reports Server (NTRS)

Bond, F. E.

1979-01-01

Large platforms have been proposed for supporting multipurpose communication payloads to exploit economy of scale, reduce congestion in the geostationary orbit, provide interconnectivity between diverse earth stations, and obtain significant frequency reuse with large multibeam antennas. This paper addresses a specific system design, starting with traffic projections in the next two decades and discussing tradeoffs and design approaches for major components including: antennas, transponders, and switches. Other issues explored are selection of frequency bands, modulation, multiple access, switching methods, and techniques for servicing areas with nonuniform traffic demands. Three-major services are considered: a high-volume trunking system, a direct-to-user system, and a broadcast system for video distribution and similar functions. Estimates of payload weight and d.c. power requirements are presented. Other subjects treated are: considerations of equipment layout for servicing by an orbit transfer vehicle, mechanical stability requirements for the large antennas, and reliability aspects of the large number of transponders employed.

Application of Fiber-Optical Techniques in the Access Transmission and Backbone Transport of Mobile Networks

NASA Astrophysics Data System (ADS)

Hilt, Attila; Pozsonyi, László

2012-09-01

Fixed access networks widely employ fiber-optical techniques due to the extremely wide bandwidth offered to subscribers. In the last decade, there has also been an enormous increase of user data visible in mobile systems. The importance of fiber-optical techniques within the fixed transmission/transport networks of mobile systems is therefore inevitably increasing. This article summarizes a few reasons and gives examples why and how fiber-optic techniques are employed efficiently in second-generation networks.

Positive correlation of employment and psychological well-being for veterans with major abdominal surgery.

PubMed

Horner, David J; Wendel, Christopher S; Skeps, Raymond; Rawl, Susan M; Grant, Marcia; Schmidt, C Max; Ko, Clifford Y; Krouse, Robert S

2010-11-01

Intestinal stomas (ostomies) have been associated negatively with multiple aspects of health-related quality of life. This article examines the relationship between employment status and psychological well-being (PWB) in veterans who underwent major bowel procedures with or without ostomy. Veterans from 3 Veterans Affairs (VA) medical centers were surveyed using the City of Hope ostomy-specific questionnaire and the Short Form 36 item Veteran's version (SF-36V). Response rate was 48% (511 of 1,063). Employment and PWB relationship was assessed using multiple regression with age, income, SF-36V physical component summary (PCS), and employment status as independent variables. Employed veterans reported higher PWB compared with unemployed veterans (P = .003). Full-time workers also reported higher PWB than part-time or unemployed workers (P = .001). Ostomy was not an independent predictor of PWB. Employment among veterans after major abdominal surgery may have intrinsic value for PWB. Patients should be encouraged to return to work, or do volunteer work after recovery. Published by Elsevier Inc.

AAA and AXB algorithms for the treatment of nasopharyngeal carcinoma using IMRT and RapidArc techniques.

PubMed

Kamaleldin, Maha; Elsherbini, Nader A; Elshemey, Wael M

2017-09-27

The aim of this study is to evaluate the impact of anisotropic analytical algorithm (AAA) and 2 reporting systems (AXB-D m and AXB-D w ) of Acuros XB algorithm (AXB) on clinical plans of nasopharyngeal patients using intensity-modulated radiotherapy (IMRT) and RapidArc (RA) techniques. Six plans of different algorithm-technique combinations are performed for 10 patients to calculate dose-volume histogram (DVH) physical parameters for planning target volumes (PTVs) and organs at risk (OARs). The number of monitor units (MUs) and calculation time are also determined. Good coverage is reported for all algorithm-technique combination plans without exceeding the tolerance for OARs. Regardless of the algorithm, RA plans persistently reported higher D 2% values for PTV-70. All IMRT plans reported higher number of MUs (especially with AXB) than did RA plans. AAA-IMRT produced the minimum calculation time of all plans. Major differences between the investigated algorithm-technique combinations are reported only for the number of MUs and calculation time parameters. In terms of these 2 parameters, it is recommended to employ AXB in calculating RA plans and AAA in calculating IMRT plans to achieve minimum calculation times at reduced number of MUs. Copyright © 2017 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.

Accounting for large deformations in real-time simulations of soft tissues based on reduced-order models.

PubMed

Niroomandi, S; Alfaro, I; Cueto, E; Chinesta, F

2012-01-01

Model reduction techniques have shown to constitute a valuable tool for real-time simulation in surgical environments and other fields. However, some limitations, imposed by real-time constraints, have not yet been overcome. One of such limitations is the severe limitation in time (established in 500Hz of frequency for the resolution) that precludes the employ of Newton-like schemes for solving non-linear models as the ones usually employed for modeling biological tissues. In this work we present a technique able to deal with geometrically non-linear models, based on the employ of model reduction techniques, together with an efficient non-linear solver. Examples of the performance of the technique over some examples will be given. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

3D GRASE PROPELLER: Improved Image Acquisition Technique for Arterial Spin Labeling Perfusion Imaging

PubMed Central

Tan, Huan; Hoge, W. Scott; Hamilton, Craig A.; Günther, Matthias; Kraft, Robert A.

2014-01-01

Arterial spin labeling (ASL) is a non-invasive technique that can quantitatively measure cerebral blood flow (CBF). While traditionally ASL employs 2D EPI or spiral acquisition trajectories, single-shot 3D GRASE is gaining popularity in ASL due to inherent SNR advantage and spatial coverage. However, a major limitation of 3D GRASE is through-plane blurring caused by T2 decay. A novel technique combining 3D GRASE and a PROPELLER trajectory (3DGP) is presented to minimize through-plane blurring without sacrificing perfusion sensitivity or increasing total scan time. Full brain perfusion images were acquired at a 3×3×5mm3 nominal voxel size with Q2TIPS-FAIR as the ASL preparation sequence. Data from 5 healthy subjects was acquired on a GE 1.5T scanner in less than 4 minutes per subject. While showing good agreement in CBF quantification with 3D GRASE, 3DGP demonstrated reduced through-plane blurring, improved anatomical details, high repeatability and robustness against motion, making it suitable for routine clinical use. PMID:21254211

A multispectral study of an extratropical cyclone with Nimbus 3 medium resolution infrared radiometer data

NASA Technical Reports Server (NTRS)

Holub, R.; Shenk, W. E.

1973-01-01

Four registered channels (0.2 to 4, 6.5 to 7, 10 to 11, and 20 to 23 microns) of the Nimbus 3 Medium Resolution Infrared Radiometer (MRIR) were used to study 24-hr changes in the structure of an extratropical cyclone during a 6-day period in May 1969. Use of a stereographic-horizon map projection insured that the storm was mapped with a single perspective throughout the series and allowed the convenient preparation of 24-hr difference maps of the infrared radiation fields. Single-channel and multispectral analysis techniques were employed to establish the positions and vertical slopes of jetstreams, large cloud systems, and major features of middle and upper tropospheric circulation. Use of these techniques plus the difference maps and continuity of observation allowed the early detection of secondary cyclones developing within the circulation of the primary cyclone. An automated, multispectral cloud-type identification technique was developed, and comparisons that were made with conventional ship reports and with high-resolution visual data from the image dissector camera system showed good agreement.

Managing age discrimination: an examination of the techniques used when seeking employment.

PubMed

Berger, Ellie D

2009-06-01

This article examines the age-related management techniques used by older workers in their search for employment. Data are drawn from interviews with individuals aged 45-65 years (N = 30). Findings indicate that participants develop "counteractions" and "concealments" to manage perceived age discrimination. Individuals counteract employers' ageist stereotypes by maintaining their skills and changing their work-related expectations and conceal age by altering their résumés, physical appearance, and language used. This research suggests that there is a need to reexamine the hiring practices of employers and to improve legislation in relation to their accountability.

The Role of Citizenship Performance in Academic Achievement and Graduate Employability

ERIC Educational Resources Information Center

Poropat, Arthur E.

2011-01-01

Purpose: Employability is a major educational goal, but employability programmes emphasise skill development, while employers value performance. Education acts as a model for employment, so educational performance assessment should be aligned with employment models. Consequently, the aim of this paper is to examine the relationship between…

Progress and challenges for abiotic stress proteomics of crop plants.

PubMed

Barkla, Bronwyn J; Vera-Estrella, Rosario; Pantoja, Omar

2013-06-01

Plants are continually challenged to recognize and respond to adverse changes in their environment to avoid detrimental effects on growth and development. Understanding the mechanisms that crop plants employ to resist and tolerate abiotic stress is of considerable interest for designing agriculture breeding strategies to ensure sustainable productivity. The application of proteomics technologies to advance our knowledge in crop plant abiotic stress tolerance has increased dramatically in the past few years as evidenced by the large amount of publications in this area. This is attributed to advances in various technology platforms associated with MS-based techniques as well as the accessibility of proteomics units to a wider plant research community. This review summarizes the work which has been reported for major crop plants and evaluates the findings in context of the approaches that are widely employed with the aim to encourage broadening the strategies used to increase coverage of the proteome. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Detection of lack of fusion using opaque additives, phase 1

NASA Technical Reports Server (NTRS)

Cook, J. L.

1972-01-01

Two major problems in welded aluminum spacecraft structure, reliable nondestructive inspection for incomplete weldment penetration and the rapid oxidation of aluminum surfaces left exposed to the atmosphere are investigated. The approach employed to solve both problems was to employ copper as a coating to prevent oxidation of the aluminum and as an opaque additive in the weldment to enhance X-ray detection in the event of incomplete penetration. Both plasma spray and vacuum vapor deposition techniques were evaluated for depositing the copper. A series of welded panels was made using three thicknesses of vacuum-vapor-deposited copper. All weldments were nondestructively inspected by X-ray, then excised into tensile and bend specimens. Mechanical tests were conducted and all data evaluated. It was determined that the vacuum-vapor-deposited coating was superior to a plasma sprayed coating of the same thickness. The vacuum-vapor-deposited coating was more uniform in thickness, provided complete coverage of the aluminum, and was free of cracks and porosity.

Enhanced Delivery of Gold Nanoparticles with Therapeutic Potential into the Brain using MRI-Guided Focused Ultrasound

PubMed Central

Etame, Arnold B.; Diaz, Roberto J.; O’Reilly, Meaghan A.; Smith, Christian A.; Mainprize, Todd G.; Hynynen, Kullervo; Rutka, James T.

2014-01-01

The blood brain barrier (BBB) is a major impediment to the delivery of therapeutics into the central nervous system (CNS). Gold nanoparticles (AuNPs) have been successfully employed in multiple potential therapeutic and diagnostic applications outside the CNS. However, AuNPs have very limited biodistribution within the CNS following intravenous administration. Magnetic resonance imaging guided focused ultrasound (MRgFUS) is a novel technique that can transiently increase BBB permeability allowing delivery of therapeutics into the CNS. MRgFUS has not been previously employed for delivery of AuNPs into the CNS. This work represents the first demonstration of focal enhanced delivery of AuNPs into the CNS using MRgFUS in a rat model both safely and effectively. Histologic visualization and analytical quantification of AuNPs within the brain parenchyma suggest BBB transgression. These results suggest a role for MRgFUS in the delivery of AuNPs with therapeutic potential into the CNS for targeting neurological diseases. PMID:22349099

Solving an inverse eigenvalue problem with triple constraints on eigenvalues, singular values, and diagonal elements

NASA Astrophysics Data System (ADS)

Wu, Sheng-Jhih; Chu, Moody T.

2017-08-01

An inverse eigenvalue problem usually entails two constraints, one conditioned upon the spectrum and the other on the structure. This paper investigates the problem where triple constraints of eigenvalues, singular values, and diagonal entries are imposed simultaneously. An approach combining an eclectic mix of skills from differential geometry, optimization theory, and analytic gradient flow is employed to prove the solvability of such a problem. The result generalizes the classical Mirsky, Sing-Thompson, and Weyl-Horn theorems concerning the respective majorization relationships between any two of the arrays of main diagonal entries, eigenvalues, and singular values. The existence theory fills a gap in the classical matrix theory. The problem might find applications in wireless communication and quantum information science. The technique employed can be implemented as a first-step numerical method for constructing the matrix. With slight modification, the approach might be used to explore similar types of inverse problems where the prescribed entries are at general locations.

Surgical techniques influence local environment of injured spinal cord and cause various grafted cell survival and integration.

PubMed

Hou, Shaoping; Saltos, Tatiana M; Iredia, Idiata W; Tom, Veronica J

2018-01-01

Cellular transplantation to repair a complete spinal cord injury (SCI) is tremendously challenging due to the adverse local milieu for graft survival and growth. Results from cell transplantation studies yield great variability, which may possibly be due to the surgical techniques employed to induce an SCI. In order to delineate the influence of surgery on such inconsistency, we compared lesion morphology and graft survival as well as integration from different lesion methodologies of SCI. Surgical techniques, including a traditional approach cut+microaspiration, and two new approaches, cut alone as well as crush, were employed to produce a complete SCI, respectively. Approximately half of the rats in each group received injury only, whereas the other half received grafts of fetal brainstem cells into the lesion gap. Eight weeks after injury with or without graft, histological analysis showed that the cut+microaspiration surgery resulted in larger lesion cavities and severe fibrotic scars surrounding the cavity, and cellular transplants rarely formed a tissue bridge to penetrate the barrier. In contrast, the majority of cases treated with cut alone or crush exhibited smaller cavities and less scarring; the grafts expanded and blended extensively with the host tissue, which often built continuous tissue bridging the rostral and caudal cords. Scarring and cavitation were significantly reduced when microaspiration was avoided in SCI surgery, facilitating graft/host tissue fusion for signal transmission. The result suggests that microaspiration frequently causes severe scars and cavities, thus impeding graft survival and integration. Copyright © 2017 Elsevier B.V. All rights reserved.

Does Marital Status Influence the Parenting Styles Employed by Parents?

ERIC Educational Resources Information Center

Ashiono, Benard Litali; Mwoma, Teresa B.

2015-01-01

The current study sought to establish whether parents' marital status, influence their use of specific parenting styles in Kisauni District, Kenya. A correlational research design was employed to carry out this study. Stratified sampling technique was used to select preschools while purposive sampling technique was used to select preschool…

Pedagogical Techniques Employed by the Television Show "MythBusters"

ERIC Educational Resources Information Center

Zavrel, Erik

2016-01-01

"MythBusters," the long-running though recently discontinued Discovery Channel science entertainment television program, has proven itself to be far more than just a highly rated show. While its focus is on entertainment, the show employs an array of pedagogical techniques to communicate scientific concepts to its audience. These…

Multiple Employment Training Programs. Major Overhaul Needed To Reduce Costs, Streamline the Bureaucracy, and Improve Results. Testimony before the Committee on Labor and Human Resources. U.S. Senate.

ERIC Educational Resources Information Center

Crawford, Clarence C.

Research conducted by the General Accounting Office (GAO) indicates that the current system of multiple employment training programs requires major overhaul to reduce costs, streamline the bureaucracy, and improve results. The current system of 163 different federal employment training programs wastes resources and confuses and frustrates clients,…

In the foot steps of Madame Curie: A cross-case study of female undergraduate physics majors

NASA Astrophysics Data System (ADS)

Jaladanki, Vani Savithri

Females are disproportionately underrepresented in STEM (science, technology, engineering, and mathematics) majors. Further, the number of females who take physics in college has declined. While female students make up 61% of graduates in biological sciences and 50% in chemistry, the proportion of women completing physics degrees is only 21% (Sawtelle, 2011). In order to improve women's access to science and engineering education, research must focus on personal and environmental factors that motivate them to select these fields (AAUW, 2010). The purpose of this study was to explore how the educational experiences of three female undergraduate physics majors contribute to their current dispositions toward, interest in, and pursuit of physics as a major at a large southern research university. This qualitative study employs symbolic interactionism (Blumer, 1969) as its methodological framework and social cognitive career theory (Lent, Brown, & Hackett, 2002) as its theoretical framework. Case study methods (Yin, 2006) were implemented to investigate the experiences of three participants. The primary sources of data included critical incident interviews (Flanagan, 1954), photographs, documents, object elicitations, and the researcher's reflections. Narrative and arts-based techniques were employed to analyze and represent data. Findings are presented as co-constructed narratives of the participants' journeys to becoming undergraduate physics majors. Three major themes emerged from the cross case analysis: carving new spaces, authoring an empowered self, and show me you care and so will I. The direct experiences of engaging with science at a young age and social persuasions of family members, teachers, and peers strongly influenced the participants' interest in and pursuit of physics. Their current dispositions to physics result from vicarious experiences with professors and peers in combination with the social persuasions of the latter. This study informs science educators in general, and physics educators in particular, about how to motivate and enable female students to engage with physics and possibly pursue it as a career choice. Three major implications for practice were suggested: teach science as a vibrant field, enable students to understand failure as an opportunity to succeed, and shift the focus from competition to collaboration.

Use of internet by the teaching faculty of Peshawar Medical College, Peshawar, Khyber Pakhtunkhwa, Pakistan.

PubMed

Jan, Saeedullah; Hussain, Abid; Ibrahim, Muhammad; Saeed, Sarah

2018-03-01

This study was planned to examine the hard and soft form of learning resources available on the internet accessed by the teaching faculty. This study was conducted at the Peshawar Medical College, Peshawar, Pakistan from January 2to April 2017. As the target population was not too large, no sampling technique was employed and census-based approach was adopted. For data collection, the pre-tested questionnaire was distributed among 115 faculty members of both basic and clinical sciences groups with a response rate of 66(57.39%). Data was analysed using SPSS. Among the respondents, 38(57.6%) were males and 28(42.4%) were females. A majority 51 (77.27%) of the respondents used the internet for teaching and research. Library was the most frequently 22 (33.33%) used place for the internet use. Low internet speed, virus on computers and a lack of modern trainings were the major barriers. E-journals, e-books, online databases and theses and dissertations were the major sources consulted by the participants.

Fault detection and multiclassifier fusion for unmanned aerial vehicles (UAVs)

NASA Astrophysics Data System (ADS)

Yan, Weizhong

2001-03-01

UAVs demand more accurate fault accommodation for their mission manager and vehicle control system in order to achieve a reliability level that is comparable to that of a pilot aircraft. This paper attempts to apply multi-classifier fusion techniques to achieve the necessary performance of the fault detection function for the Lockheed Martin Skunk Works (LMSW) UAV Mission Manager. Three different classifiers that meet the design requirements of the fault detection of the UAAV are employed. The binary decision outputs from the classifiers are then aggregated using three different classifier fusion schemes, namely, majority vote, weighted majority vote, and Naieve Bayes combination. All of the three schemes are simple and need no retraining. The three fusion schemes (except the majority vote that gives an average performance of the three classifiers) show the classification performance that is better than or equal to that of the best individual. The unavoidable correlation between the classifiers with binary outputs is observed in this study. We conclude that it is the correlation between the classifiers that limits the fusion schemes to achieve an even better performance.

Development of transgenic cotton lines expressing Allium sativum agglutinin (ASAL) for enhanced resistance against major sap-sucking pests.

PubMed

Vajhala, Chakravarthy S K; Sadumpati, Vijaya Kumar; Nunna, Hariprasad Rao; Puligundla, Sateesh Kumar; Vudem, Dashavantha Reddy; Khareedu, Venkateswara Rao

2013-01-01

Mannose-specific Allium sativum leaf agglutinin encoding gene (ASAL) and herbicide tolerance gene (BAR) were introduced into an elite cotton inbred line (NC-601) employing Agrobacterium-mediated genetic transformation. Cotton transformants were produced from the phosphinothricin (PPT)-resistant shoots obtained after co-cultivation of mature embryos with the Agrobacterium strain EHA105 harbouring recombinant binary vector pCAMBIA3300-ASAL-BAR. PCR and Southern blot analysis confirmed the presence and stable integration of ASAL and BAR genes in various transformants of cotton. Basta leaf-dip assay, northern blot, western blot and ELISA analyses disclosed variable expression of BAR and ASAL transgenes in different transformants. Transgenes, ASAL and BAR, were stably inherited and showed co-segregation in T1 generation in a Mendelian fashion for both PPT tolerance and insect resistance. In planta insect bioassays on T2 and T3 homozygous ASAL-transgenic lines revealed potent entomotoxic effects of ASAL on jassid and whitefly insects, as evidenced by significant decreases in the survival, development and fecundity of the insects when compared to the untransformed controls. Furthermore, the transgenic cotton lines conferred higher levels of resistance (1-2 score) with minimal plant damage against these major sucking pests when bioassays were carried out employing standard screening techniques. The developed transgenics could serve as a potential genetic resource in recombination breeding aimed at improving the pest resistance of cotton. This study represents the first report of its kind dealing with the development of transgenic cotton resistant to two major sap-sucking insects.

Development of Transgenic Cotton Lines Expressing Allium sativum Agglutinin (ASAL) for Enhanced Resistance against Major Sap-Sucking Pests

PubMed Central

Nunna, Hariprasad Rao; Puligundla, Sateesh Kumar; Vudem, Dashavantha Reddy; Khareedu, Venkateswara Rao

2013-01-01

Mannose-specific Allium sativum leaf agglutinin encoding gene (ASAL) and herbicide tolerance gene (BAR) were introduced into an elite cotton inbred line (NC-601) employing Agrobacterium-mediated genetic transformation. Cotton transformants were produced from the phosphinothricin (PPT)-resistant shoots obtained after co-cultivation of mature embryos with the Agrobacterium strain EHA105 harbouring recombinant binary vector pCAMBIA3300-ASAL-BAR. PCR and Southern blot analysis confirmed the presence and stable integration of ASAL and BAR genes in various transformants of cotton. Basta leaf-dip assay, northern blot, western blot and ELISA analyses disclosed variable expression of BAR and ASAL transgenes in different transformants. Transgenes, ASAL and BAR, were stably inherited and showed co-segregation in T1 generation in a Mendelian fashion for both PPT tolerance and insect resistance. In planta insect bioassays on T2 and T3 homozygous ASAL-transgenic lines revealed potent entomotoxic effects of ASAL on jassid and whitefly insects, as evidenced by significant decreases in the survival, development and fecundity of the insects when compared to the untransformed controls. Furthermore, the transgenic cotton lines conferred higher levels of resistance (1–2 score) with minimal plant damage against these major sucking pests when bioassays were carried out employing standard screening techniques. The developed transgenics could serve as a potential genetic resource in recombination breeding aimed at improving the pest resistance of cotton. This study represents the first report of its kind dealing with the development of transgenic cotton resistant to two major sap-sucking insects. PMID:24023750

Police training in interviewing and interrogation methods: A comparison of techniques used with adult and juvenile suspects.

PubMed

Cleary, Hayley M D; Warner, Todd C

2016-06-01

Despite empirical progress in documenting and classifying various interrogation techniques, very little is known about how police are trained in interrogation methods, how frequently they use various techniques, and whether they employ techniques differentially with adult versus juvenile suspects. This study reports the nature and extent of formal (e.g., Reid Technique, PEACE, HUMINT) and informal interrogation training as well as self-reported technique usage in a diverse national sample (N = 340) of experienced American police officers. Officers were trained in a variety of different techniques ranging from comparatively benign pre-interrogation strategies (e.g., building rapport, observing body language or speech patterns) to more psychologically coercive techniques (e.g., blaming the victim, discouraging denials). Over half the sample reported being trained to use psychologically coercive techniques with both adults and juveniles. The majority (91%) receive informal, "on the job" interrogation training. Technique usage patterns indicate a spectrum of psychological intensity where information-gathering approaches were used most frequently and high-pressure tactics less frequently. Reid-trained officers (56%) were significantly more likely than officers without Reid training to use pre-interrogation and manipulation techniques. Across all analyses and techniques, usage patterns were identical for adult and juvenile suspects, suggesting that police interrogate youth in the same manner as adults. Overall, results suggest that training in specific interrogation methods is strongly associated with usage. Findings underscore the need for more law enforcement interrogation training in general, especially with juvenile suspects, and highlight the value of training as an avenue for reducing interrogation-induced miscarriages of justice. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Development and application of computational aerothermodynamics flowfield computer codes

NASA Technical Reports Server (NTRS)

Venkatapathy, Ethiraj

1993-01-01

Computations are presented for one-dimensional, strong shock waves that are typical of those that form in front of a reentering spacecraft. The fluid mechanics and thermochemistry are modeled using two different approaches. The first employs traditional continuum techniques in solving the Navier-Stokes equations. The second-approach employs a particle simulation technique (the direct simulation Monte Carlo method, DSMC). The thermochemical models employed in these two techniques are quite different. The present investigation presents an evaluation of thermochemical models for nitrogen under hypersonic flow conditions. Four separate cases are considered. The cases are governed, respectively, by the following: vibrational relaxation; weak dissociation; strong dissociation; and weak ionization. In near-continuum, hypersonic flow, the nonequilibrium thermochemical models employed in continuum and particle simulations produce nearly identical solutions. Further, the two approaches are evaluated successfully against available experimental data for weakly and strongly dissociating flows.

40 CFR 426.135 - Standards of performance for new sources.

Code of Federal Regulations, 2013 CFR

2013-07-01

... greater than 50 gallons per day of process waste water, and employs hydrofluoric acid finishing techniques... any 1 day Average of daily values for 30 consecutive days shall not exceed— Lead 0.2 0.1 Fluoride 26.0... waste water, and employs hydrofluoric acid finishing techniques shall meet the following limitations...

40 CFR 426.135 - Standards of performance for new sources.

Code of Federal Regulations, 2012 CFR

2012-07-01

... greater than 50 gallons per day of process waste water, and employs hydrofluoric acid finishing techniques... any 1 day Average of daily values for 30 consecutive days shall not exceed— Lead 0.2 0.1 Fluoride 26.0... waste water, and employs hydrofluoric acid finishing techniques shall meet the following limitations...

40 CFR 426.135 - Standards of performance for new sources.

Code of Federal Regulations, 2014 CFR

2014-07-01

... greater than 50 gallons per day of process waste water, and employs hydrofluoric acid finishing techniques... any 1 day Average of daily values for 30 consecutive days shall not exceed— Lead 0.2 0.1 Fluoride 26.0... waste water, and employs hydrofluoric acid finishing techniques shall meet the following limitations...

Managing Age Discrimination: An Examination of the Techniques Used when Seeking Employment

ERIC Educational Resources Information Center

Berger, Ellie D.

2009-01-01

Purpose: This article examines the age-related management techniques used by older workers in their search for employment. Design and Methods: Data are drawn from interviews with individuals aged 45-65 years (N = 30). Results: Findings indicate that participants develop "counteractions" and "concealments" to manage perceived age discrimination.…

Use of benchmarking techniques to justify the evolution of antibiotic management programs in healthcare systems.

PubMed

Schentag, J J; Paladino, J A; Birmingham, M C; Zimmer, G; Carr, J R; Hanson, S C

1995-01-01

To apply basic benchmarking techniques to hospital antibiotic expenditures and clinical pharmacy personnel and their duties, to identify cost savings strategies for clinical pharmacy services. Prospective survey of 18 hospitals ranging in size from 201 to 942 beds. Each was asked to provide antibiotic expenditures, an overview of their clinical pharmacy services, and to describe the duties of clinical pharmacists involved in antibiotic management activities. Specific information was sought on the use of pharmacokinetic dosing services, antibiotic streamlining, and oral switch in each of the hospitals. Most smaller hospitals (< 300 beds) did not employ clinical pharmacists with the specific duties of antibiotic management or streamlining. At these institutions, antibiotic management services consisted of formulary enforcement and aminoglycoside and/or vancomycin dosing services. The larger hospitals we surveyed employed clinical pharmacists designated as antibiotic management specialists, but their usual activities were aminoglycoside and/or vancomycin dosing services and formulary enforcement. In virtually all hospitals, the yearly expenses for antibiotics exceeded those of Millard Fillmore Hospitals by $2,000-3,000 per occupied bed. In a 500-bed hospital, this difference in expenditures would exceed $1.5 million yearly. Millard Fillmore Health System has similar types of patients, but employs clinical pharmacists to perform streamlining and/or switch functions at days 2-4, when cultures come back from the laboratory. The antibiotic streamlining and oral switch duties of clinical pharmacy specialists are associated with the majority of cost savings in hospital antibiotic management programs. The savings are considerable to the extent that most hospitals with 200-300 beds could readily cost-justify a full-time clinical pharmacist to perform these activities on a daily basis. Expenses of the program would be offset entirely by the reduction in the actual pharmacy expenditures on antibiotics.

Photoacoustic sensor for VOCs: first step towards a lung cancer breath test

NASA Astrophysics Data System (ADS)

Wolff, Marcus; Groninga, Hinrich G.; Dressler, Matthias; Harde, Hermann

2005-08-01

Development of new optical sensor technologies has a major impact on the progression of diagnostic methods. Specifically, the optical analysis of breath is an extraordinarily promising technique. Spectroscopic sensors for the non-invasive 13C-breath tests (the Urea Breath Test for detection of Helicobacter pylori is most prominent) are meanwhile well established. However, recent research and development go beyond gastroenterological applications. Sensitive and selective detection of certain volatile organic compounds (VOCs) in a patient's breath, could enable the diagnosis of diseases that are very difficult to diagnose with contemporary techniques. For instance, an appropriate VOC biomarker for early-stage bronchial carcinoma (lung cancer) is n-butane (C4H10). We present a new optical detection scheme for VOCs that employs an especially compact and simple set-up based on photoacoustic spectroscopy (PAS). This method makes use of the transformation of absorbed modulated radiation into a sound wave. Employing a wavelength-modulated distributed feedback (DFB) diode laser and taking advantage of acoustical resonances of the sample cell, we performed very sensitive and selective measurements on butane. A detection limit for butane in air in the ppb range was achieved. In subsequent research the sensitivity will be successively improved to match the requirements of the medical application. Upon optimization, our photoacoustic sensor has the potential to enable future breath tests for early-stage lung cancer diagnostics.

Evaluation of cross-polarized near infrared hyperspectral imaging for early detection of dental caries

NASA Astrophysics Data System (ADS)

Usenik, Peter; Bürmen, Miran; Fidler, Aleš; Pernuš, Franjo; Likar, Boštjan

2012-01-01

Despite major improvements in dental healthcare and oral hygiene, dental caries remains one of the most prevalent oral diseases and represents the primary cause of oral pain and tooth loss. The initial stages of dental caries are characterized by demineralization of enamel crystals and are difficult to diagnose. Near infrared (NIR) hyperspectral imaging is a new promising technique for detection of early changes in the surfaces of carious teeth. This noninvasive imaging technique can characterize and differentiate between the sound tooth surface and initial or advanced tooth caries. The absorbing and scattering properties of dental tissues reflect in distinct spectral features, which can be measured, quantified and used to accurately classify and map different dental tissues. Specular reflections from the tooth surface, which appear as bright spots, mostly located around the edges and the crests of the teeth, act as a noise factor which can significantly interfere with the spectral measurements and analysis of the acquired images, degrading the accuracy of the classification and diagnosis. Employing cross-polarized imaging setup can solve this problem, however has yet to be systematically evaluated, especially in broadband hyperspectral imaging setups. In this paper, we employ cross-polarized illumination setup utilizing state-of-the-art high-contrast broadband wire-grid polarizers in the spectral range from 900 nm to 1700 nm for hyperspectral imaging of natural and artificial carious lesions of various degrees.

Chlorophyll fluorescence emission as a reporter on cold tolerance in Arabidopsis thaliana accessions

PubMed Central

Mishra, Anamika; Höermiller, Imke I; Heyer, Arnd G; Nedbal, Ladislav

2011-01-01

Non-invasive, high-throughput screening methods are valuable tools in breeding for abiotic stress tolerance in plants. Optical signals such as chlorophyll fluorescence emission can be instrumental in developing new screening techniques. In order to examine the potential of chlorophyll fluorescence to reveal plant tolerance to low temperatures, we used a collection of nine Arabidopsis thaliana accessions and compared their fluorescence features with cold tolerance quantified by the well established electrolyte leakage method on detached leaves. We found that, during progressive cooling, the minimal chlorophyll fluorescence emission rose strongly and that this rise was highly dependent on the cold tolerance of the accessions. Maximum quantum yield of PSII photochemistry and steady state fluorescence normalized to minimal fluorescence were also highly correlated to the cold tolerance measured by the electrolyte leakage method. In order to further increase the capacity of the fluorescence detection to reveal the low temperature tolerance, we applied combinatorial imaging that employs plant classification based on multiple fluorescence features. We found that this method, by including the resolving power of several fluorescence features, can be well employed to detect cold tolerance already at mild sub-zero temperatures. Therefore, there is no need to freeze the screened plants to the largely damaging temperatures of around −15°C. This, together with the method's easy applicability, represents a major advantage of the fluorescence technique over the conventional electrolyte leakage method. PMID:21427532

Compressive Sampling Based Interior Reconstruction for Dynamic Carbon Nanotube Micro-CT

PubMed Central

Yu, Hengyong; Cao, Guohua; Burk, Laurel; Lee, Yueh; Lu, Jianping; Santago, Pete; Zhou, Otto; Wang, Ge

2010-01-01

In the computed tomography (CT) field, one recent invention is the so-called carbon nanotube (CNT) based field emission x-ray technology. On the other hand, compressive sampling (CS) based interior tomography is a new innovation. Combining the strengths of these two novel subjects, we apply the interior tomography technique to local mouse cardiac imaging using respiration and cardiac gating with a CNT based micro-CT scanner. The major features of our method are: (1) it does not need exact prior knowledge inside an ROI; and (2) two orthogonal scout projections are employed to regularize the reconstruction. Both numerical simulations and in vivo mouse studies are performed to demonstrate the feasibility of our methodology. PMID:19923686

Pediatric Headache: An Overview.

PubMed

Langdon, Raquel; DiSabella, Marc T

2017-03-01

Headache represents the most common neurologic disorder in the general population including children and is increasingly being recognized as a major source of morbidity in youth related to missed school days and activities. In this article, we take a holistic approach to the child presenting with headache with a focus on the detailed headache history, physical and neurologic examinations, and diagnostic evaluation of these patients. Clinical presentations and classification schema of multiple primary and secondary headache types in children are discussed using the International Headache Criteria (IHCD-3) as a guide, and a summary provided of the various treatment modalities employed for pediatric headache including lifestyle modifications, behavioral techniques, and abortive and preventive medications. Copyright © 2017 Mosby, Inc. All rights reserved.

Reasoning about Codata

NASA Astrophysics Data System (ADS)

Hinze, Ralf

Programmers happily use induction to prove properties of recursive programs. To show properties of corecursive programs they employ coinduction, but perhaps less enthusiastically. Coinduction is often considered a rather low-level proof method, in particular, as it departs quite radically from equational reasoning. Corecursive programs are conveniently defined using recursion equations. Suitably restricted, these equations possess unique solutions. Uniqueness gives rise to a simple and attractive proof technique, which essentially brings equational reasoning to the coworld. We illustrate the approach using two major examples: streams and infinite binary trees. Both coinductive types exhibit a rich structure: they are applicative functors or idioms, and they can be seen as memo-tables or tabulations. We show that definitions and calculations benefit immensely from this additional structure.

Transitions of Care Model Inclusive of Unplanned Care Improves the Patient Experience

PubMed Central

Cox, Jon; Teague, Stephanie; Beck, Eric

2016-01-01

A major emphasis in health care is creating an experience whereby patients receive the right care at the right time from the right provider in the right setting at the right cost. Over the past several decades, there has been considerable effort in the area of medical management, with prior authorization, gatekeeper utilization management regimens, and other techniques designed to guide patients and caregivers into desired treatment pathways. Alternatively, the concept of demand management may be employed to achieve these desired outcomes by giving patients meaningful, expanded choices beyond traditional acute-care settings. The implementation of a novel, patient-centered, unplanned care delivery model is described along with illustrative case studies. PMID:28725828

Cholesterol granuloma of the petrous apex: establishment of a drainage route into the superior tympanic cavity--technical note.

PubMed

Kamiguchi, H; Kawase, T; Toya, S; Inoue, Y

1996-09-01

A 40-year-old male presented with a cholesterol granuloma of the petrous apex manifesting as progressive hearing loss and tinnitus. The lesion was treated via an extradural middle cranial fossa approach employing a new procedure to establish a drainage pathway into the superior tympanic cavity which preserved his hearing. The pathway was formed by a groove 5 mm wide and deep in the anterolateral aspect of the petrous bone, crossing the major petrosal nerve and carotid artery, running around the cochlea, crossing the tensor tympanic muscle, and entering the superior tympanic cavity above the orifice of the eustachian tube. This procedure is easy to perform without special techniques.

High-pressure torsion for new hydrogen storage materials

PubMed Central

Edalati, Kaveh; Akiba, Etsuo; Horita, Zenji

2018-01-01

Abstract High-pressure torsion (HPT) is widely used as a severe plastic deformation technique to create ultrafine-grained structures with promising mechanical and functional properties. Since 2007, the method has been employed to enhance the hydrogenation kinetics in different Mg-based hydrogen storage materials. Recent studies showed that the method is effective not only for increasing the hydrogenation kinetics but also for improving the hydrogenation activity, for enhancing the air resistivity and more importantly for synthesizing new nanostructured hydrogen storage materials with high densities of lattice defects. This manuscript reviews some major findings on the impact of HPT process on the hydrogen storage performance of different titanium-based and magnesium-based materials. PMID:29511396

Ares I Flight Control System Overview

NASA Technical Reports Server (NTRS)

Hall, Charles; Lee, Chong; Jackson, Mark; Whorton, Mark; West, mark; Brandon, Jay; Hall, Rob A.; Jang, Jimmy; Bedrossian, Naz; Compton, Jimmy;

Resisting the "Employability" Doctrine through Anarchist Pedagogies & Prefiguration

ERIC Educational Resources Information Center

Osborne, Natalie; Grant-Smith, Deanna

2017-01-01

Increasingly those working in higher education are tasked with targeting their teaching approaches and techniques to improve the "employability" of graduates. However, this approach is promoted with little recognition that enhanced employability does not guarantee employment outcomes or the tensions inherent in pursuing this agenda. The…

Hamilton County: A Rural School District Profile.

ERIC Educational Resources Information Center

Harned, Catherine

Using state education agency, census, industry employment and occupational information data, this paper provides a detailed picture of a rural school district in Southern Illinois. Mining and agriculture are the major industries in Hamilton County. The major mining employer closed in February 1988, and the drought of 1988 is likely to adversely…

Hospitalization Risk Before and After Employment Among Adults With Schizophrenia, Bipolar Disorder, or Major Depression.

PubMed

Luciano, Alison; Metcalfe, Justin D; Bond, Gary R; Xie, Haiyi; Miller, Alexander L; Riley, Jarnee; O'Malley, A James; Drake, Robert E

2016-10-01

The influence of employment on subsequent psychiatric hospitalization for people with serious mental illness is unclear. This study examined whether unemployed people with serious mental illness were more or less likely to experience psychiatric hospitalization after gaining employment. A secondary analysis was conducted of data from the Mental Health Treatment Study. Two years of prospective employment and psychiatric hospital outcomes were examined for 2,055 adults with schizophrenia, bipolar disorder, or major depression. The analyses examined associations between employment and psychiatric hospitalization via multilevel regression by using time-lagged modeling. Employment was associated with a lower subsequent three-month risk of psychiatric hospitalization (odds ratio=.65, 95% confidence interval=.50-.84) after the analysis adjusted for baseline characteristics, including previous psychiatric hospitalizations and self-reported physical health. Unemployed outpatients with serious mental illness were less likely to experience psychiatric hospitalization after gaining employment.

Secretarial Administraton: The Interviewing Process.

ERIC Educational Resources Information Center

Nemesh, Anna

1979-01-01

Suggests classroom techniques to prepare business students for employment interviews and gives information on lawful and unlawful employment interview inquiries, as well as some fair employment legal requirements of the Equal Employment Opportunity Act of 1974, Civil Rights Act of 1964, Equal Pay Act of 1963, and Rehabilitation Act of 1973. (MF)

The Corrosion Protection of Magnesium Alloy AZ31B

NASA Technical Reports Server (NTRS)

Danford, M. D.; Mendrek, M. J.; Mitchell, M. L.; Torres, P. D.

1997-01-01

Corrosion rates for bare and coated Magnesium alloy AZ31B have been measured. Two coatings, Dow-23(Trademark) and Tagnite(Trademark), have been tested by electrochemical methods and their effectiveness determined. Electrochemical methods employed were the scanning reference electrode technique (SRET), the polarization resistance technique (PR) and the electrochemical impedance spectroscopy technique (EIS). In addition, general corrosion and stress corrosion methods were employed to examine the effectiveness of the above coatings in 90 percent humidity. Results from these studies are presented.

Comparison of X-Ray Micro-Tomography Measurements of Densities and Porosity to Traditional Techniques for Carbon-Carbon Composites

DTIC Science & Technology

2009-02-26

equation, nitrogen , argon, and krypton are employed while for the D-R equation CO2 is usually used . With the adsorption techniques, certain assumption...structure to characterize it. Lastly, other liquids are used in a density gradient column [73-75] employing a sink-float technique in an attempt to...least 147 incremental intrusion pressures to 275 kPa, using nitrogen gas as the displacing medium. The sample is then loaded into the high-pressure

User-Centered Innovation: A Model for "Early Usability Testing."

ERIC Educational Resources Information Center

Sugar, William A.; Boling, Elizabeth

The goal of this study is to show how some concepts and techniques from disciplines outside Instructional Systems Development (ISD) have the potential to extend and enhance the traditional view of ISD practice when they are employed very early in the ISD process. The concepts and techniques employed were user-centered in design and usability, and…

Employ Simulation Techniques. Second Edition. Module C-5 of Category C--Instructional Execution. Professional Teacher Education Module Series.

ERIC Educational Resources Information Center

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

One of a series of performance-based teacher education learning packages focusing upon specific professional competencies of vocational teachers, this learning module deals with employing simulation techniques. It consists of an introduction and four learning experiences. Covered in the first learning experience are various types of simulation…

Professionals' views of fetal-monitoring support the development of devices to provide objective longer-term assessment of fetal wellbeing.

PubMed

Brown, Rebecca; Johnstone, Edward D; Heazell, Alexander E P

2016-01-01

Continuous longer-term fetal monitoring has been proposed to address limitations of current technologies in the detection of fetal compromise. We aimed to assess professionals' views regarding current fetal-monitoring techniques and proposed longer-term continuous fetal monitoring. A questionnaire was designed and validated to assess obstetricians' and midwives' use of current fetal-monitoring techniques and their views towards continuous monitoring. 125 of 173 received responses (72% obstetricians, 28% midwives) were analysed. Professionals had the strongest views about supporting evidence for the most commonly employed fetal-monitoring techniques (maternal awareness of fetal movements, ultrasound assessment of fetal growth and umbilical artery Doppler). 45.1% of professionals agreed that a continuous monitoring device would be beneficial (versus 28.7% who disagreed); this perceived benefit was not influenced by professionals' views regarding current techniques or professional background. Professionals have limited experience of continuous fetal monitoring, but most respondents believed that it would increase maternal anxiety (64.3%) and would have concerns with its use in clinical practice (81.7%). Continuous fetal monitoring would be acceptable to the majority of professionals. However, development of these technologies must be accompanied by extended examination of professionals' and women's views to determine barriers to its introduction.

Impact of Fatigue in Rheumatic Diseases in the Work Environment: A Qualitative Study.

PubMed

Connolly, Deirdre; Fitzpatrick, Clodagh; O'Toole, Lynn; Doran, Michele; O'Shea, Finbar

2015-10-28

Fatigue is a symptom of arthritis that causes difficulty at work. An improved understanding of this symptom could assist its management in the work environment. The aim of this study was to explore people with rheumatic diseases' experiences of fatigue in work. A qualitative descriptive design was used with semi-structured interviews and a constant comparative method of data analysis. There were 18 participants, the majority of them female with Rheumatoid Arthritis (RA) and working full-time. Three themes were identified: "Impact of fatigue on work performance" with cognition, mood and physical abilities being the main difficulties reported. In the second theme "Disclosure at Work" participants discussed disclosing their disease to employers but reported a lack of understanding of fatigue from colleagues. The final theme "work-based fatigue management strategies" included cognitive strategies and energy management techniques, which were mainly self-taught. In this study, fatigue was reported to impact on many areas of work performance with limited understanding from colleagues and employers. Interventions from health professionals to assist with development of work-related self-management skills are required to assist with symptom management in the work place. Such interventions should include education to employers and colleagues on the nature of fatigue in Rheumatic diseases.

Impact of Fatigue in Rheumatic Diseases in the Work Environment: A Qualitative Study

PubMed Central

Connolly, Deirdre; Fitzpatrick, Clodagh; O’Toole, Lynn; Doran, Michele; O’Shea, Finbar

2015-01-01

Fatigue is a symptom of arthritis that causes difficulty at work. An improved understanding of this symptom could assist its management in the work environment. The aim of this study was to explore people with rheumatic diseases’ experiences of fatigue in work. A qualitative descriptive design was used with semi-structured interviews and a constant comparative method of data analysis. There were 18 participants, the majority of them female with Rheumatoid Arthritis (RA) and working full-time. Three themes were identified: “Impact of fatigue on work performance” with cognition, mood and physical abilities being the main difficulties reported. In the second theme “Disclosure at Work” participants discussed disclosing their disease to employers but reported a lack of understanding of fatigue from colleagues. The final theme “work-based fatigue management strategies” included cognitive strategies and energy management techniques, which were mainly self-taught. In this study, fatigue was reported to impact on many areas of work performance with limited understanding from colleagues and employers. Interventions from health professionals to assist with development of work-related self-management skills are required to assist with symptom management in the work place. Such interventions should include education to employers and colleagues on the nature of fatigue in Rheumatic diseases. PMID:26516896

Reducing the decline in physical activity during pregnancy: a systematic review of behaviour change interventions.

PubMed

Currie, Sinead; Sinclair, Marlene; Murphy, Marie H; Madden, Elaine; Dunwoody, Lynn; Liddle, Dianne

2013-01-01

Physical activity (PA) typically declines throughout pregnancy. Low levels of PA are associated with excessive weight gain and subsequently increase risk of pre-eclampsia, gestational diabetes mellitus, hypertension disorders, delivery by caesarean section and stillbirth. Systematic reviews on PA during pregnancy have not explored the efficacy of behaviour change techniques or related theory in altering PA behaviour. This systematic review evaluated the content of PA interventions to reduce the decline of PA in pregnant women with a specific emphasis on the behaviour change techniques employed to elicit this change. Literature searches were conducted in eight databases. Strict inclusion and exclusion criteria were employed. Two reviewers independently evaluated each intervention using the behaviour change techniques (BCT) taxonomy to identify the specific behaviour change techniques employed. Two reviewers independently assessed the risk of bias using the guidelines from the Cochrane Collaboration. Overall quality was determined using the GRADE approach. A total of 1140 potentially eligible papers were identified from which 14 studies were selected for inclusion. Interventions included counselling (n = 6), structured exercise (n = 6) and education (n = 2). Common behaviour change techniques employed in these studies were goal setting and planning, feedback, repetition and substitution, shaping knowledge and comparison of behaviours. Regular face-to-face meetings were also commonly employed. PA change over time in intervention groups ranged from increases of 28% to decreases of 25%. In 8 out of 10 studies, which provided adequate data, participants in the intervention group were more physically active post intervention than controls. Physical activity interventions incorporating behaviour change techniques help reduce the decline in PA throughout pregnancy. Range of behaviour change techniques can be implemented to reduce this decline including goals and planning, shaping knowledge and comparison of outcomes. A lack of high quality interventions hampers conclusions of intervention effectiveness.

A "good practice" approach to the quality and consistency of morphological examination of the internal head structures of the term rabbit fetus.

PubMed

French, Julian M

2014-07-01

Variation in the interpretation of the regulatory guidelines has resulted in a diversity of techniques employed to examine the internal structures of the foetal rabbit head. Examination of the foetal rabbit brain, using a single transverse section as the sole technique, is considered not to be sufficiently thorough to be regarded as an adequate examination method. It is not compliant with published EPA and OECD guidelines covering required examination of the internal head structures, nor is it considered to conform to the spirit of the safety assessment required by the ICH guideline. Fixation of approximately half of the heads in each litter to allow the examination of multiple transverse sections enables the major structures within the head to be assessed effectively. This method is compliant with current guidelines, represents "good practice" and should be consistently adopted for the examination of the internal head structures of the term rabbit foetus. Copyright © 2014 Elsevier Inc. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nagakura, Hiroki; Iwakami, Wakana; Furusawa, Shun

We present a newly developed moving-mesh technique for the multi-dimensional Boltzmann-Hydro code for the simulation of core-collapse supernovae (CCSNe). What makes this technique different from others is the fact that it treats not only hydrodynamics but also neutrino transfer in the language of the 3 + 1 formalism of general relativity (GR), making use of the shift vector to specify the time evolution of the coordinate system. This means that the transport part of our code is essentially general relativistic, although in this paper it is applied only to the moving curvilinear coordinates in the flat Minknowski spacetime, since the gravity partmore » is still Newtonian. The numerical aspect of the implementation is also described in detail. Employing the axisymmetric two-dimensional version of the code, we conduct two test computations: oscillations and runaways of proto-neutron star (PNS). We show that our new method works fine, tracking the motions of PNS correctly. We believe that this is a major advancement toward the realistic simulation of CCSNe.« less

Elemental investigation of Syrian medicinal plants using PIXE analysis

NASA Astrophysics Data System (ADS)

Rihawy, M. S.; Bakraji, E. H.; Aref, S.; Shaban, R.

2010-09-01

Particle induced X-ray emission (PIXE) technique has been employed to perform elemental analysis of K, Ca, Mn, Fe, Cu, Zn, Br and Sr for Syrian medicinal plants used traditionally to enhance the body immunity. Plant samples were prepared in a simple dried base. The results were verified by comparing with those obtained from both IAEA-359 and IAEA-V10 reference materials. Relative standard deviations are mostly within ±5-10% suggest good precision. A correlation between the elemental content in each medicinal plant with its traditional remedial usage has been proposed. Both K and Ca are found to be the major elements in the samples. Fe, Mn and Zn have been detected in good levels in most of these plants clarifying their possible contribution to keep the body immune system in good condition. The contribution of the elements in these plants to the dietary recommended intakes (DRI) has been evaluated. Advantages and limitations of PIXE analytical technique in this investigation have been reviewed.

Isotope labeled immunoassay for environmental chemical detection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Velez, M.M.

1994-05-06

Altrazine, one of the most heavily used agricultural pesticides in North America, has been identified as a major groundwater contaminant in the U.S. Research provides evidence that under certain conditions atrazine and some of its derivatives may prove to be carcinogenic and mutagenic. Immunossays are one of the most powerful of all analytical immunochemical techniques. They employ a wide range of methods to detect and quantitate antigens or antibodies, and to study the structure of antigens. With the appropriate assay, they can be remarkably quick and easy, to yield information that would be difficult to determine by other techniques. Themore » development of the appropriate assay; however, requires clean and precise separation of antigens bound to antibodies from those that remain free. Sensitive assays depend on quantification of these bound antigens at very low levels. We are making direct and competitive immunoassays with atrazine and its antibodies using accelerator mass spectrometry (AMS) in order to obtain a sensitive immunoassay for atrazine in environmental samples.« less

Entropy-based adaptive attitude estimation

NASA Astrophysics Data System (ADS)

Kiani, Maryam; Barzegar, Aylin; Pourtakdoust, Seid H.

2018-03-01

Gaussian approximation filters have increasingly been developed to enhance the accuracy of attitude estimation in space missions. The effective employment of these algorithms demands accurate knowledge of system dynamics and measurement models, as well as their noise characteristics, which are usually unavailable or unreliable. An innovation-based adaptive filtering approach has been adopted as a solution to this problem; however, it exhibits two major challenges, namely appropriate window size selection and guaranteed assurance of positive definiteness for the estimated noise covariance matrices. The current work presents two novel techniques based on relative entropy and confidence level concepts in order to address the abovementioned drawbacks. The proposed adaptation techniques are applied to two nonlinear state estimation algorithms of the extended Kalman filter and cubature Kalman filter for attitude estimation of a low earth orbit satellite equipped with three-axis magnetometers and Sun sensors. The effectiveness of the proposed adaptation scheme is demonstrated by means of comprehensive sensitivity analysis on the system and environmental parameters by using extensive independent Monte Carlo simulations.

Tracking performance under time sharing conditions with a digit processing task: A feedback control theory analysis. [attention sharing effect on operator performance

NASA Technical Reports Server (NTRS)

Gopher, D.; Wickens, C. D.

1975-01-01

A one dimensional compensatory tracking task and a digit processing reaction time task were combined in a three phase experiment designed to investigate tracking performance in time sharing. Adaptive techniques, elaborate feedback devices, and on line standardization procedures were used to adjust task difficulty to the ability of each individual subject and manipulate time sharing demands. Feedback control analysis techniques were employed in the description of tracking performance. The experimental results show that when the dynamics of a system are constrained, in such a manner that man machine system stability is no longer a major concern of the operator, he tends to adopt a first order control describing function, even with tracking systems of higher order. Attention diversion to a concurrent task leads to an increase in remnant level, or nonlinear power. This decrease in linearity is reflected both in the output magnitude spectra of the subjects, and in the linear fit of the amplitude ratio functions.

A quality monitor and monitoring technique employing optically stimulated electron emission

NASA Technical Reports Server (NTRS)

Yost, William T. (Inventor); Welch, Christopher S. (Inventor); Joe, Edmond J. (Inventor); Hefner, Bill Bryan, Jr. (Inventor)

1995-01-01

A light source directs ultraviolet light onto a test surface and a detector detects a current of photoelectrons generated by the light. The detector includes a collector which is positively biased with respect to the test surface. Quality is indicated based on the photoelectron current. The collector is then negatively biased to replace charges removed by the measurement of a nonconducting substrate to permit subsequent measurements. Also, the intensity of the ultraviolet light at a particular wavelength is monitored and the voltage of the light source varied to maintain the light a constant desired intensity. The light source is also cooled via a gas circulation system. If the test surface is an insulator, the surface is bombarded with ultraviolet light in the presence of an electron field to remove the majority of negative charges from the surface. The test surface is then exposed to an ion field until it possesses no net charge. The technique described above is then performed to assess quality.

Study on the interaction of the epilepsy drug, zonisamide with human serum albumin (HSA) by spectroscopic and molecular docking techniques

NASA Astrophysics Data System (ADS)

Shahabadi, Nahid; Khorshidi, Aref; Moghadam, Neda Hossinpour

2013-10-01

In the present investigation, an attempt has been made to study the interaction of zonisamide (ZNS) with the transport protein, human serum albumin (HSA) employing UV-Vis, fluorometric, circular dichroism (CD) and molecular docking techniques. The results indicated that binding of ZNS to HSA caused strong fluorescence quenching of HSA through static quenching mechanism, hydrogen bonds and van der Waals contacts are the major forces in the stability of protein ZNS complex and the process of the binding of ZNS with HSA was driven by enthalpy (ΔH = -193.442 kJ mol-1). The results of CD and UV-Vis spectroscopy showed that the binding of this drug to HSA induced conformational changes in HSA. Furthermore, the study of molecular docking also indicated that zonisamide could strongly bind to the site I (subdomain IIA) of HSA mainly by hydrophobic interaction and there were hydrogen bond interactions between this drug and HSA, also known as the warfarin binding site.

Unlocking the secrets to protein–protein interface drug targets using structural mass spectrometry techniques

PubMed Central

Dailing, Angela; Luchini, Alessandra; Liotta, Lance

2016-01-01

Protein–protein interactions (PPIs) drive all biologic systems at the subcellular and extracellular level. Changes in the specificity and affinity of these interactions can lead to cellular malfunctions and disease. Consequently, the binding interfaces between interacting protein partners are important drug targets for the next generation of therapies that block such interactions. Unfortunately, protein–protein contact points have proven to be very difficult pharmacological targets because they are hidden within complex 3D interfaces. For the vast majority of characterized binary PPIs, the specific amino acid sequence of their close contact regions remains unknown. There has been an important need for an experimental technology that can rapidly reveal the functionally important contact points of native protein complexes in solution. In this review, experimental techniques employing mass spectrometry to explore protein interaction binding sites are discussed. Hydrogen–deuterium exchange, hydroxyl radical footprinting, crosslinking and the newest technology protein painting, are compared and contrasted. PMID:26400464

A scheme to calculate higher-order homogenization as applied to micro-acoustic boundary value problems

NASA Astrophysics Data System (ADS)

Vagh, Hardik A.; Baghai-Wadji, Alireza

2008-12-01

Current technological challenges in materials science and high-tech device industry require the solution of boundary value problems (BVPs) involving regions of various scales, e.g. multiple thin layers, fibre-reinforced composites, and nano/micro pores. In most cases straightforward application of standard variational techniques to BVPs of practical relevance necessarily leads to unsatisfactorily ill-conditioned analytical and/or numerical results. To remedy the computational challenges associated with sub-sectional heterogeneities various sophisticated homogenization techniques need to be employed. Homogenization refers to the systematic process of smoothing out the sub-structural heterogeneities, leading to the determination of effective constitutive coefficients. Ordinarily, homogenization involves a sophisticated averaging and asymptotic order analysis to obtain solutions. In the majority of the cases only zero-order terms are constructed due to the complexity of the processes involved. In this paper we propose a constructive scheme for obtaining homogenized solutions involving higher order terms, and thus, guaranteeing higher accuracy and greater robustness of the numerical results. We present

Multi-Modal Nano-Probes for Radionuclide and 5-color Near Infrared Optical Lymphatic Imaging

PubMed Central

Kobayashi, Hisataka; Koyama, Yoshinori; Barrett, Tristan; Hama, Yukihiro; Regino, Celeste A. S.; Shin, In Soo; Jang, Beom-Su; Le, Nhat; Paik, Chang H.; Choyke, Peter L.; Urano, Yasuteru

2008-01-01

Current contrast agents generally have one function and can only be imaged in monochrome, therefore, the majority of imaging methods can only impart uniparametric information. A single nano-particle has the potential to be loaded with multiple payloads. Such multi-modality probes have the ability to be imaged by more than one imaging technique, which could compensate for the weakness or even combine the advantages of each individual modality. Furthermore, optical imaging using different optical probes enables us to achieve multi-color in vivo imaging, wherein multiple parameters can be read from a single image. To allow differentiation of multiple optical signals in vivo, each probe should have a close but different near infrared emission. To this end, we synthesized nano-probes with multi-modal and multi-color potential, which employed a polyamidoamine dendrimer platform linked to both radionuclides and optical probes, permitting dual-modality scintigraphic and 5-color near infrared optical lymphatic imaging using a multiple excitation spectrally-resolved fluorescence imaging technique. PMID:19079788

Multimodal nanoprobes for radionuclide and five-color near-infrared optical lymphatic imaging.

PubMed

Kobayashi, Hisataka; Koyama, Yoshinori; Barrett, Tristan; Hama, Yukihiro; Regino, Celeste A S; Shin, In Soo; Jang, Beom-Su; Le, Nhat; Paik, Chang H; Choyke, Peter L; Urano, Yasuteru

2007-11-01

Current contrast agents generally have one function and can only be imaged in monochrome; therefore, the majority of imaging methods can only impart uniparametric information. A single nanoparticle has the potential to be loaded with multiple payloads. Such multimodality probes have the ability to be imaged by more than one imaging technique, which could compensate for the weakness or even combine the advantages of each individual modality. Furthermore, optical imaging using different optical probes enables us to achieve multicolor in vivo imaging, wherein multiple parameters can be read from a single image. To allow differentiation of multiple optical signals in vivo, each probe should have a close but different near-infrared emission. To this end, we synthesized nanoprobes with multimodal and multicolor potential, which employed a polyamidoamine dendrimer platform linked to both radionuclides and optical probes, permitting dual-modality scintigraphic and five-color near-infrared optical lymphatic imaging using a multiple-excitation spectrally resolved fluorescence imaging technique.

Quality improving techniques for free-viewpoint DIBR

NASA Astrophysics Data System (ADS)

Do, Luat; Zinger, Sveta; de With, Peter H. N.

2010-02-01

Interactive free-viewpoint selection applied to a 3D multi-view signal is a possible attractive feature of the rapidly developing 3D TV media. This paper explores a new rendering algorithm that computes a free-viewpoint based on depth image warping between two reference views from existing cameras. We have developed three quality enhancing techniques that specifically aim at solving the major artifacts. First, resampling artifacts are filled in by a combination of median filtering and inverse warping. Second, contour artifacts are processed while omitting warping of edges at high discontinuities. Third, we employ a depth signal for more accurate disocclusion inpainting. We obtain an average PSNR gain of 3 dB and 4.5 dB for the 'Breakdancers' and 'Ballet' sequences, respectively, compared to recently published results. While experimenting with synthetic data, we observe that the rendering quality is highly dependent on the complexity of the scene. Moreover, experiments are performed using compressed video from surrounding cameras. The overall system quality is dominated by the rendering quality and not by coding.

A hybrid neural networks-fuzzy logic-genetic algorithm for grade estimation

NASA Astrophysics Data System (ADS)

Tahmasebi, Pejman; Hezarkhani, Ardeshir

2012-05-01

The grade estimation is a quite important and money/time-consuming stage in a mine project, which is considered as a challenge for the geologists and mining engineers due to the structural complexities in mineral ore deposits. To overcome this problem, several artificial intelligence techniques such as Artificial Neural Networks (ANN) and Fuzzy Logic (FL) have recently been employed with various architectures and properties. However, due to the constraints of both methods, they yield the desired results only under the specific circumstances. As an example, one major problem in FL is the difficulty of constructing the membership functions (MFs).Other problems such as architecture and local minima could also be located in ANN designing. Therefore, a new methodology is presented in this paper for grade estimation. This method which is based on ANN and FL is called "Coactive Neuro-Fuzzy Inference System" (CANFIS) which combines two approaches, ANN and FL. The combination of these two artificial intelligence approaches is achieved via the verbal and numerical power of intelligent systems. To improve the performance of this system, a Genetic Algorithm (GA) - as a well-known technique to solve the complex optimization problems - is also employed to optimize the network parameters including learning rate, momentum of the network and the number of MFs for each input. A comparison of these techniques (ANN, Adaptive Neuro-Fuzzy Inference System or ANFIS) with this new method (CANFIS-GA) is also carried out through a case study in Sungun copper deposit, located in East-Azerbaijan, Iran. The results show that CANFIS-GA could be a faster and more accurate alternative to the existing time-consuming methodologies for ore grade estimation and that is, therefore, suggested to be applied for grade estimation in similar problems.

A hybrid neural networks-fuzzy logic-genetic algorithm for grade estimation

PubMed Central

Tahmasebi, Pejman; Hezarkhani, Ardeshir

2012-01-01

The grade estimation is a quite important and money/time-consuming stage in a mine project, which is considered as a challenge for the geologists and mining engineers due to the structural complexities in mineral ore deposits. To overcome this problem, several artificial intelligence techniques such as Artificial Neural Networks (ANN) and Fuzzy Logic (FL) have recently been employed with various architectures and properties. However, due to the constraints of both methods, they yield the desired results only under the specific circumstances. As an example, one major problem in FL is the difficulty of constructing the membership functions (MFs).Other problems such as architecture and local minima could also be located in ANN designing. Therefore, a new methodology is presented in this paper for grade estimation. This method which is based on ANN and FL is called “Coactive Neuro-Fuzzy Inference System” (CANFIS) which combines two approaches, ANN and FL. The combination of these two artificial intelligence approaches is achieved via the verbal and numerical power of intelligent systems. To improve the performance of this system, a Genetic Algorithm (GA) – as a well-known technique to solve the complex optimization problems – is also employed to optimize the network parameters including learning rate, momentum of the network and the number of MFs for each input. A comparison of these techniques (ANN, Adaptive Neuro-Fuzzy Inference System or ANFIS) with this new method (CANFIS–GA) is also carried out through a case study in Sungun copper deposit, located in East-Azerbaijan, Iran. The results show that CANFIS–GA could be a faster and more accurate alternative to the existing time-consuming methodologies for ore grade estimation and that is, therefore, suggested to be applied for grade estimation in similar problems. PMID:25540468

Employment Trends in Computer Occupations. Bulletin 2101.

ERIC Educational Resources Information Center

Howard, H. Philip; Rothstein, Debra E.

In 1980 1,455,000 persons worked in computer occupations. Two in five were systems analysts or programmers; one in five was a keypunch operator; one in 20 was a computer service technician; and more than one in three were computer and peripheral equipment operators. Employment was concentrated in major urban centers in four major industry…

The Lie Detector in Employment; An Examination of Some of the Problems. Key Issues Series. Number 2.

ERIC Educational Resources Information Center

Coghill, Mary Ann; Gruenfeld, Elaine F.

In a review of personnel polygraphing, the history of the polygraph technique is discussed. Since it is a controversial technique used by employers to test employees' honesty and loyalty by measuring physiological reactions, an increasing number of States and localities are taking legal action to prevent its use. The results of several arbitration…

Application of redundancy in the Saturn 5 guidance and control system

NASA Technical Reports Server (NTRS)

Moore, F. B.; White, J. B.

1976-01-01

The Saturn launch vehicle's guidance and control system is so complex that the reliability of a simplex system is not adequate to fulfill mission requirements. Thus, to achieve the desired reliability, redundancy encompassing a wide range of types and levels was employed. At one extreme, the lowest level, basic components (resistors, capacitors, relays, etc.) are employed in series, parallel, or quadruplex arrangements to insure continued system operation in the presence of possible failure conditions. At the other extreme, the highest level, complete subsystem duplication is provided so that a backup subsystem can be employed in case the primary system malfunctions. In between these two extremes, many other redundancy schemes and techniques are employed at various levels. Basic redundancy concepts are covered to gain insight into the advantages obtained with various techniques. Points and methods of application of these techniques are included. The theoretical gain in reliability resulting from redundancy is assessed and compared to a simplex system. Problems and limitations encountered in the practical application of redundancy are discussed as well as techniques verifying proper operation of the redundant channels. As background for the redundancy application discussion, a basic description of the guidance and control system is included.

Inverse Problems in Geodynamics Using Machine Learning Algorithms

NASA Astrophysics Data System (ADS)

Shahnas, M. H.; Yuen, D. A.; Pysklywec, R. N.

2018-01-01

During the past few decades numerical studies have been widely employed to explore the style of circulation and mixing in the mantle of Earth and other planets. However, in geodynamical studies there are many properties from mineral physics, geochemistry, and petrology in these numerical models. Machine learning, as a computational statistic-related technique and a subfield of artificial intelligence, has rapidly emerged recently in many fields of sciences and engineering. We focus here on the application of supervised machine learning (SML) algorithms in predictions of mantle flow processes. Specifically, we emphasize on estimating mantle properties by employing machine learning techniques in solving an inverse problem. Using snapshots of numerical convection models as training samples, we enable machine learning models to determine the magnitude of the spin transition-induced density anomalies that can cause flow stagnation at midmantle depths. Employing support vector machine algorithms, we show that SML techniques can successfully predict the magnitude of mantle density anomalies and can also be used in characterizing mantle flow patterns. The technique can be extended to more complex geodynamic problems in mantle dynamics by employing deep learning algorithms for putting constraints on properties such as viscosity, elastic parameters, and the nature of thermal and chemical anomalies.

Disabled Veterans of the Vietnam Era: Employment Problems and Programs. Technical Report No. 75-1.

ERIC Educational Resources Information Center

Wilson, Thurlow R.; And Others

The report describes the results of a study of the employment of Vietnam-era veterans with service-connected disabilities, their major problems in seeking and holding a job, and possible solutions. Data were obtained from; mail surveys of both disabled veterans and employers regarding employment; personal interviews with veterans and employers;…

Personal value preferences, group identifications, and cultural practices of Palestinian Israelis working in close contact with Jewish Israelis.

PubMed

Tartakovsky, Eugene; Abu Kheit, Ayat

2017-01-01

The present study investigates the connection between personal value preferences, group identifications, and cultural practices among Palestinian Israelis working in close contact with the Jewish population in Israel. One hundred twenty-two Palestinian Israelis participated in the study. The participants were employed in different professional positions in the Tel Aviv Metropolitan area and were recruited to the study using the snowball technique. A stronger national identification was associated with a higher preference for the security and conformity values, and a lower preference for the humility values. A stronger ethnic identification was associated with a lower preference for the security, power, and stimulation values. Group identifications mediated the connection between personal value preferences and cultural practices. A longer time working in close contact with the majority group and less frequent visits home were associated with a greater adherence to the majority group's cultural practices but not with adherence to the ethnic group's practices and not with the group identifications.

Quantitative gel electrophoresis: new records in precision by elaborated staining and detection protocols.

PubMed

Deng, Xi; Schröder, Simone; Redweik, Sabine; Wätzig, Hermann

2011-06-01

Gel electrophoresis (GE) is a very common analytical technique for proteome research and protein analysis. Despite being developed decades ago, there is still a considerable need to improve its precision. Using the fluorescence of Colloidal Coomassie Blue -stained proteins in near-infrared (NIR), the major error source caused by the unpredictable background staining is strongly reduced. This result was generalized for various types of detectors. Since GE is a multi-step procedure, standardization of every single step is required. After detailed analysis of all steps, the staining and destaining were identified as the major source of the remaining variation. By employing standardized protocols, pooled percent relative standard deviations of 1.2-3.1% for band intensities were achieved for one-dimensional separations in repetitive experiments. The analysis of variance suggests that the same batch of staining solution should be used for gels of one experimental series to minimize day-to-day variation and to obtain high precision. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Investigation of Inner Loop Flight Control Strategies for High-Speed Research

NASA Technical Reports Server (NTRS)

Newman, Brett; Kassem, Ayman

1999-01-01

This report describes the activities and findings conducted under contract NAS1-19858 with NASA Langley Research Center. Subject matter is the investigation of suitable flight control design methodologies and solutions for large, flexible high-speed vehicles. Specifically, methodologies are to address the inner control loops used for stabilization and augmentation of a highly coupled airframe system possibly involving rigid-body motion, structural vibrations, unsteady aerodynamics, and actuator dynamics. Techniques considered in this body of work are primarily conventional-based, and the vehicle of interest is the High-Speed Civil Transport (HSCT). Major findings include 1) current aeroelastic vehicle modeling procedures require further emphasis and refinement, 2) traditional and nontraditional inner loop flight control strategies employing a single feedback loop do not appear sufficient for highly flexible HSCT class vehicles, 3) inner loop flight control systems will, in all likelihood, require multiple interacting feedback loops, and 4) Ref. H HSCT configuration presents major challenges to designing acceptable closed-loop flight dynamics.

The Investigation of the Impact of SO2 Emissions from the Hong Kong International Airport

NASA Astrophysics Data System (ADS)

Gray, J. P.; Lau, A. K.; Yuan, Z.

2009-12-01

A previous study of the emissions from Hong Kong’s International Airport (HKIA) utilized a semi-quantitative wind direction and speed technique and identified HKIA as a significant source of SO2 in the region. This study however was based on a single data point and the conclusions reached appeared to be inconsistent with accepted thinking regarding aircraft and airport emissions, prompting an in-depth look at airport emissions and their impact on neighbouring region. Varied modelling techniques, making use of a more complete dataset, were employed to ensure a more comprehensive and defensible result. A similar analysis technique and the same monitoring station used in the previous study (Tung Chung) were combined with three additional stations to provided coverage to reach more certain conclusions. While results at Tung Chung were similar to those in the previous study, information from the other three sensors pointed to a source further to the north in the direction of the Black Point Coal Power Station and other power plants further to the north in Mainland China. This conclusion was confirmed by use of the CALMET / CALPUFF model to reproduce emission plumes from major sources within the region on problem days. The modelled results clearly showed that, in the cases simulated, pollution events noted at Tung Chung were primarily influenced by emissions originating at Hong Kong’s and Mainland China’s power stations, and the impact from HKIA is small. This study reiterates the importance of proper identification of all major sources in wind receptor type studies.

Vascular labeling of the head and neck vessels: Technique, advantages and limitations.

PubMed

Gálvez, Alba; Caraballo, José-Leonardo; Manzanares-Céspedes, María-Cristina; Valdivia-Gandur, Iván; Figueiredo, Rui; Valmaseda-Castellón, Eduard

2017-05-01

Vascular staining techniques have been used to describe the vascular structures of several anatomic areas. However, few reports have described this procedure in the head and neck region. This paper describes a head and neck vascular labeling procedure, and describes some of the technical complications that may occur. Fifteen specimen cadaver heads were prepared. After drying the vascular system, the internal carotid arteries were ligated and a solution with latex and a gelling agent was injected into the internal carotid arteries and external jugular veins. Two different colors were employed to differentiate arteries from veins. A total of 60ml latex was injected into each blood vessel. Subsequently, the specimens were refrigerated at 5°C for a minimum of 24 hours. Finally, a dissection was performed to identify the venous and arterial systems of the maxillofacial region. In most specimens, correct identification of the vascular structures (lingual artery, pterigoyd plexus, and the major palatal arteries, among others) was possible. However, in three heads a major technical problem occurred (the latex remained liquid), making the dissection unfeasible. Other minor complications such as latex obstruction due to the presence of atheromas were found in two further specimens. The vascular labeling technique is a predictable, effective and simple method for analyzing the vascular system of the maxillofacial area in cadaveric studies, including vessels of reduced diameter or with an intraosseous course. This procedure can be especially useful to teach vascular anatomy to dental students and postgraduate residents. Key words: Blood vessels, vascular casting, vascular labeling, head and neck arteries, carotid arteries, jugular veins.

77 FR 25225 - 60-Day Notice of Proposed Information Collection: DS 7655, Iraqi Citizens and Nationals Employed...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-27

... the use of automated collection techniques or other forms of technology. Abstract of Proposed..., date(s) of employment, biometric, and other data must be collected and used to verify employment for...

Multivariate analysis of remote LIBS spectra using partial least squares, principal component analysis, and related techniques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clegg, Samuel M; Barefield, James E; Wiens, Roger C

2008-01-01

Quantitative analysis with LIBS traditionally employs calibration curves that are complicated by the chemical matrix effects. These chemical matrix effects influence the LIBS plasma and the ratio of elemental composition to elemental emission line intensity. Consequently, LIBS calibration typically requires a priori knowledge of the unknown, in order for a series of calibration standards similar to the unknown to be employed. In this paper, three new Multivariate Analysis (MV A) techniques are employed to analyze the LIBS spectra of 18 disparate igneous and highly-metamorphosed rock samples. Partial Least Squares (PLS) analysis is used to generate a calibration model from whichmore » unknown samples can be analyzed. Principal Components Analysis (PCA) and Soft Independent Modeling of Class Analogy (SIMCA) are employed to generate a model and predict the rock type of the samples. These MV A techniques appear to exploit the matrix effects associated with the chemistries of these 18 samples.« less

Leishmania amazonensis fails to induce the release of reactive oxygen intermediates by CBA macrophages.

PubMed

Almeida, T F; Palma, L C; Mendez, L C; Noronha-Dutra, A A; Veras, P S T

2012-10-01

CBA mouse macrophages effectively control Leishmania major infection, yet are permissive to Leishmania amazonensis. It has been established that some Leishmania species are destroyed by reactive oxygen species (ROS). However, other species of Leishmania exhibit resistance to ROS or even down-modulate ROS production. We hypothesized that L. amazonensis-infected macrophages reduce ROS production soon after parasite-cell interaction. Employing a highly sensitive analysis technique based on chemiluminescence, the production of superoxide (O(·-)(2)) and hydrogen peroxide (H(2)O(2)) by L. major- or L. amazonensis-infected CBA macrophages were measured. L. major induces macrophages to release levels of (O(·-)(2)) 3·5 times higher than in uninfected cells. This (O(·-)(2)) production is partially dependent on NADPH oxidase (NOX) type 2. The level of accumulated H(2)O(2) is 20 times higher in L. major-than in L. amazonensis-infected cells. Furthermore, macrophages stimulated with L. amazonensis release amounts of ROS similar to uninfected cells. These findings support previous studies showing that CBA macrophages are effective in controlling L. major infection by a mechanism dependent on both (O(·-)(2)) production and H(2)O(2) generation. Furthermore, these data reinforce the notion that L. amazonensis survive inside CBA macrophages by reducing ROS production during the phagocytic process. © 2012 Blackwell Publishing Ltd.

Project Employability: Work Performance Handbook for Special Education Students.

ERIC Educational Resources Information Center

Burrell, Lewis P.; Talarico, Robert L.

The Student Work Performance Handbook is the sixth in a series from Project Employability (Ohio) designed to meet employability needs of trainable and educable mentally retarded high school students. The handbook is organized into five major components: (1) knowledge factors about applying for and securing employment (job sources, job application…

A versatile breast reduction technique: Conical plicated central U shaped (COPCUs) mammaplasty

PubMed Central

Copcu, Eray

2009-01-01

Background There have been numerous studies on reduction mammaplasty and its modifications in the literature. The multitude of modifications of reduction mammaplasty indicates that the ideal technique has yet to be found. There are four reasons for seeking the ideal technique. One reason is to preserve functional features of the breast: breastfeeding and arousal. Other reasons are to achieve the real geometric and aesthetic shape of the breast with the least scar and are to minimize complications of prior surgical techniques without causing an additional complication. Last reason is the limitation of the techniques described before. To these aims, we developed a new versatile reduction mammaplasty technique, which we called conical plicated central U shaped (COPCUs) mammaplasty. Methods We performed central plication to achieve a juvenile look in the superior pole of the breast and to prevent postoperative pseudoptosis and used central U shaped flap to achieve maximum NAC safety and to preserve lactation and nipple sensation. The central U flap was 6 cm in width and the superior conical plication was performed with 2/0 PDS. Preoperative and postoperative standard measures of the breast including the superior pole fullness were compared. Results Forty six patients were operated with the above mentioned technique. All of the patients were satisfied with functional and aesthetic results and none of them had major complications. There were no changes in the nipple innervation. Six patients becoming pregnant after surgery did not experience any problems with lactation. None of the patients required scar revision. Conclusion Our technique is a versatile, safe, reliable technique which creates the least scar, avoids previously described disadvantages, provides maximum preservation of functions, can be employed in all breasts regardless of their sizes. PMID:19575809

Microwave, Millimeter, Submillimeter, and Far Infrared Spectral Databases

NASA Technical Reports Server (NTRS)

Pearson, J. C.; Pickett, H. M.; Drouin, B. J.; Chen, P.; Cohen, E. A.

2002-01-01

The spectrum of most known astrophysical molecules is derived from transitions between a few hundred to a few hundred thousand energy levels populated at room temperature. In the microwave and millimeter wave regions. spectroscopy is almost always performed with traditional microwave techniques. In the submillimeter and far infrared microwave technique becomes progressively more technologically challenging and infrared techniques become more widely employed as the wavelength gets shorter. Infrared techniques are typically one to two orders of magnitude less precise but they do generate all the strong features in the spectrum. With microwave technique, it is generally impossible and rarely necessary to measure every single transition of a molecular species, so careful fitting of quantum mechanical Hamiltonians to the transitions measured are required to produce the complete spectral picture of the molecule required by astronomers. The fitting process produces the most precise data possible and is required in the interpret heterodyne observations. The drawback of traditional microwave technique is that precise knowledge of the band origins of low lying excited states is rarely gained. The fitting of data interpolates well for the range of quantum numbers where there is laboratory data, but extrapolation is almost never precise. The majority of high resolution spectroscopic data is millimeter or longer in wavelength and a very limited number of molecules have ever been studied with microwave techniques at wavelengths shorter than 0.3 millimeters. The situation with infrared technique is similarly dire in the submillimeter and far infrared because the black body sources used are competing with a very significant thermal background making the signal to noise poor. Regardless of the technique used the data must be archived in a way useful for the interpretation of observations.

Comparative analysis of essential oil composition of Iranian and Indian Nigella sativa L. extracted using supercritical fluid extraction and solvent extraction

PubMed Central

Ghahramanloo, Kourosh Hasanzadeh; Kamalidehghan, Behnam; Akbari Javar, Hamid; Teguh Widodo, Riyanto; Majidzadeh, Keivan; Noordin, Mohamed Ibrahim

2017-01-01

The objective of this study was to compare the oil extraction yield and essential oil composition of Indian and Iranian Nigella sativa L. extracted by using Supercritical Fluid Extraction (SFE) and solvent extraction methods. In this study, a gas chromatography equipped with a mass spectrophotometer detector was employed for qualitative analysis of the essential oil composition of Indian and Iranian N. sativa L. The results indicated that the main fatty acid composition identified in the essential oils extracted by using SFE and solvent extraction were linoleic acid (22.4%–61.85%) and oleic acid (1.64%–18.97%). Thymoquinone (0.72%–21.03%) was found to be the major volatile compound in the extracted N. sativa oil. It was observed that the oil extraction efficiency obtained from SFE was significantly (P<0.05) higher than that achieved by the solvent extraction technique. The present study showed that SFE can be used as a more efficient technique for extraction of N. Sativa L. essential oil, which is composed of higher linoleic acid and thymoquinone contents compared to the essential oil obtained by the solvent extraction technique. PMID:28814830

Improving the efficiency of single and multiple teleportation protocols based on the direct use of partially entangled states

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fortes, Raphael; Rigolin, Gustavo, E-mail: rigolin@ifi.unicamp.br

We push the limits of the direct use of partially pure entangled states to perform quantum teleportation by presenting several protocols in many different scenarios that achieve the optimal efficiency possible. We review and put in a single formalism the three major strategies known to date that allow one to use partially entangled states for direct quantum teleportation (no distillation strategies permitted) and compare their efficiencies in real world implementations. We show how one can improve the efficiency of many direct teleportation protocols by combining these techniques. We then develop new teleportation protocols employing multipartite partially entangled states. The threemore » techniques are also used here in order to achieve the highest efficiency possible. Finally, we prove the upper bound for the optimal success rate for protocols based on partially entangled Bell states and show that some of the protocols here developed achieve such a bound. -- Highlights: •Optimal direct teleportation protocols using directly partially entangled states. •We put in a single formalism all strategies of direct teleportation. •We extend these techniques for multipartite partially entangle states. •We give upper bounds for the optimal efficiency of these protocols.« less

Application of fermentation for isoflavone extraction from soy molasses

NASA Astrophysics Data System (ADS)

Duru, K. C.; Kovaleva, E. G.; Glukhareva, T. V.

2017-09-01

Extraction of isoflavones from soy products remains a major challenge for researchers. Different extraction techniques have been employed but the need to use a cheap green extraction technique remains the main focus. This study applied fermentation of soy molasses using Saccharomyces cerevisiae for extraction of isoflavones and compared this technique to the conventional extraction method. The aluminum chloride colorimetric method was used for the determination of total flavonoid content of extracts. The highest yield was observed from extraction using ethyl acetate after fermentation of soy molasses and the lowest one was given by the extract from conventional extraction method. The DPPH radical scavenging activities of the extracts were also compared. The extract obtained using ethyl acetate after fermentation showed the highest antioxidant activity (0.0269 meq), while extract from conventional extraction had the lowest antioxidant activity (0.0055 meq). The effect of time on daidzein yield was studied using HPLC standard addition method. Daidzein concentration was higher in extract obtained at t = 80 min (3.82 ± 0.11 mg of daidzein /g of extract) as compared to that obtained at t = 60 min (2.89 ± 0.10 mg of daidzein /g of extract).

Personal photograph enhancement using internet photo collections.

PubMed

Zhang, Chenxi; Gao, Jizhou; Wang, Oliver; Georgel, Pierre; Yang, Ruigang; Davis, James; Frahm, Jan-Michael; Pollefeys, Marc

2014-02-01

Given the growth of Internet photo collections, we now have a visual index of all major cities and tourist sites in the world. However, it is still a difficult task to capture that perfect shot with your own camera when visiting these places, especially when your camera itself has limitations, such as a limited field of view. In this paper, we propose a framework to overcome the imperfections of personal photographs of tourist sites using the rich information provided by large-scale Internet photo collections. Our method deploys state-of-the-art techniques for constructing initial 3D models from photo collections. The same techniques are then used to register personal photographs to these models, allowing us to augment personal 2D images with 3D information. This strong available scene prior allows us to address a number of traditionally challenging image enhancement techniques and achieve high-quality results using simple and robust algorithms. Specifically, we demonstrate automatic foreground segmentation, mono-to-stereo conversion, field-of-view expansion, photometric enhancement, and additionally automatic annotation with geolocation and tags. Our method clearly demonstrates some possible benefits of employing the rich information contained in online photo databases to efficiently enhance and augment one's own personal photographs.

Comparative analysis of essential oil composition of Iranian and Indian Nigella sativa L. extracted using supercritical fluid extraction and solvent extraction.

PubMed

Ghahramanloo, Kourosh Hasanzadeh; Kamalidehghan, Behnam; Akbari Javar, Hamid; Teguh Widodo, Riyanto; Majidzadeh, Keivan; Noordin, Mohamed Ibrahim

2017-01-01

The objective of this study was to compare the oil extraction yield and essential oil composition of Indian and Iranian Nigella sativa L. extracted by using Supercritical Fluid Extraction (SFE) and solvent extraction methods. In this study, a gas chromatography equipped with a mass spectrophotometer detector was employed for qualitative analysis of the essential oil composition of Indian and Iranian N. sativa L. The results indicated that the main fatty acid composition identified in the essential oils extracted by using SFE and solvent extraction were linoleic acid (22.4%-61.85%) and oleic acid (1.64%-18.97%). Thymoquinone (0.72%-21.03%) was found to be the major volatile compound in the extracted N. sativa oil. It was observed that the oil extraction efficiency obtained from SFE was significantly ( P <0.05) higher than that achieved by the solvent extraction technique. The present study showed that SFE can be used as a more efficient technique for extraction of N. Sativa L. essential oil, which is composed of higher linoleic acid and thymoquinone contents compared to the essential oil obtained by the solvent extraction technique.

Reproducibility of ZrO2-based freeze casting for biomaterials.

PubMed

Naleway, Steven E; Fickas, Kate C; Maker, Yajur N; Meyers, Marc A; McKittrick, Joanna

2016-04-01

The processing technique of freeze casting has been intensely researched for its potential to create porous scaffold and infiltrated composite materials for biomedical implants and structural materials. However, in order for this technique to be employed medically or commercially, it must be able to reliably produce materials in great quantities with similar microstructures and properties. Here we investigate the reproducibility of the freeze casting process by independently fabricating three sets of eight ZrO2-epoxy composite scaffolds with the same processing conditions but varying solid loading (10, 15 and 20 vol.%). Statistical analyses (One-way ANOVA and Tukey's HSD tests) run upon measurements of the microstructural dimensions of these composite scaffold sets show that, while the majority of microstructures are similar, in all cases the composite scaffolds display statistically significant variability. In addition, composite scaffolds where mechanically compressed and statistically analyzed. Similar to the microstructures, almost all of their resultant properties displayed significant variability though most composite scaffolds were similar. These results suggest that additional research to improve control of the freeze casting technique is required before scaffolds and composite scaffolds can reliably be reproduced for commercial or medical applications. Copyright © 2015 Elsevier B.V. All rights reserved.

Computed tomography and patient risk: Facts, perceptions and uncertainties

PubMed Central

Power, Stephen P; Moloney, Fiachra; Twomey, Maria; James, Karl; O’Connor, Owen J; Maher, Michael M

2016-01-01

Since its introduction in the 1970s, computed tomography (CT) has revolutionized diagnostic decision-making. One of the major concerns associated with the widespread use of CT is the associated increased radiation exposure incurred by patients. The link between ionizing radiation and the subsequent development of neoplasia has been largely based on extrapolating data from studies of survivors of the atomic bombs dropped in Japan in 1945 and on assessments of the increased relative risk of neoplasia in those occupationally exposed to radiation within the nuclear industry. However, the association between exposure to low-dose radiation from diagnostic imaging examinations and oncogenesis remains unclear. With improved technology, significant advances have already been achieved with regards to radiation dose reduction. There are several dose optimization strategies available that may be readily employed including omitting unnecessary images at the ends of acquired series, minimizing the number of phases acquired, and the use of automated exposure control as opposed to fixed tube current techniques. In addition, new image reconstruction techniques that reduce radiation dose have been developed in recent years with promising results. These techniques use iterative reconstruction algorithms to attain diagnostic quality images with reduced image noise at lower radiation doses. PMID:28070242

Toxicophore exploration as a screening technology for drug design and discovery: techniques, scope and limitations.

PubMed

Singh, Pankaj Kumar; Negi, Arvind; Gupta, Pawan Kumar; Chauhan, Monika; Kumar, Raj

2016-08-01

Toxicity is a common drawback of newly designed chemotherapeutic agents. With the exception of pharmacophore-induced toxicity (lack of selectivity at higher concentrations of a drug), the toxicity due to chemotherapeutic agents is based on the toxicophore moiety present in the drug. To date, methodologies implemented to determine toxicophores may be broadly classified into biological, bioanalytical and computational approaches. The biological approach involves analysis of bioactivated metabolites, whereas the computational approach involves a QSAR-based method, mapping techniques, an inverse docking technique and a few toxicophore identification/estimation tools. Being one of the major steps in drug discovery process, toxicophore identification has proven to be an essential screening step in drug design and development. The paper is first of its kind, attempting to cover and compare different methodologies employed in predicting and determining toxicophores with an emphasis on their scope and limitations. Such information may prove vital in the appropriate selection of methodology and can be used as screening technology by researchers to discover the toxicophoric potentials of their designed and synthesized moieties. Additionally, it can be utilized in the manipulation of molecules containing toxicophores in such a manner that their toxicities might be eliminated or removed.

Labor Market Integration of People with Disabilities: Results from the Swiss Spinal Cord Injury Cohort Study

PubMed Central

Post, Marcel W. M.; Fekete, Christine; Trezzini, Bruno; Brinkhof, Martin W. G.

2016-01-01

Objectives We aimed to describe labor market participation (LMP) of persons with spinal cord injury (SCI) in Switzerland, to examine potential determinants of LMP, and to compare LMP between SCI and the general population. Methods We analyzed data from 1458 participants of employable age from the cross-sectional community survey of the Swiss Spinal Cord Injury Cohort Study. Data on LMP of the Swiss general population were obtained from the Swiss Federal Statistical Office. Factors associated with employment status as well as the amount of work performed in terms of full-time equivalent (FTE) were examined with regression techniques. Results 53.4% of the participants were employed at the time of the study. Adjusted odds of being employed were increased for males (OR = 1.73, 95% CI 1.33–2.25) and participants with paraplegia (OR = 1.78, 95% CI 1.40–2.27). The likelihood of being employed showed a significant concave relationship with age, peaking at age 40. The relation of LMP with education was s-shaped, while LMP was linearly related to time since injury. On average, employment rates were 30% lower than in the general population. Males with tetraplegia aged between 40 and 54 showed the greatest difference. From the 771 employed persons, the majority (81.7%) worked part-time with a median of 50% FTE (IRQ: 40%-80%). Men, those with younger age, higher education, incomplete lesions, and non-traumatic etiology showed significantly increased odds of working more hours per week. Significantly more people worked part-time than in the general population with the greatest difference found for males with tetraplegia aged between 40 and 54. Conclusions LMP of persons with SCI is comparatively high in Switzerland. LMP after SCI is, however, considerably lower than in the general population. Future research needs to show whether the reduced LMP in SCI reflects individual capacity adjustment, contextual constraints on higher LMP or both. PMID:27875566

Labor Market Integration of People with Disabilities: Results from the Swiss Spinal Cord Injury Cohort Study.

PubMed

Reinhardt, Jan D; Post, Marcel W M; Fekete, Christine; Trezzini, Bruno; Brinkhof, Martin W G

2016-01-01

We aimed to describe labor market participation (LMP) of persons with spinal cord injury (SCI) in Switzerland, to examine potential determinants of LMP, and to compare LMP between SCI and the general population. We analyzed data from 1458 participants of employable age from the cross-sectional community survey of the Swiss Spinal Cord Injury Cohort Study. Data on LMP of the Swiss general population were obtained from the Swiss Federal Statistical Office. Factors associated with employment status as well as the amount of work performed in terms of full-time equivalent (FTE) were examined with regression techniques. 53.4% of the participants were employed at the time of the study. Adjusted odds of being employed were increased for males (OR = 1.73, 95% CI 1.33-2.25) and participants with paraplegia (OR = 1.78, 95% CI 1.40-2.27). The likelihood of being employed showed a significant concave relationship with age, peaking at age 40. The relation of LMP with education was s-shaped, while LMP was linearly related to time since injury. On average, employment rates were 30% lower than in the general population. Males with tetraplegia aged between 40 and 54 showed the greatest difference. From the 771 employed persons, the majority (81.7%) worked part-time with a median of 50% FTE (IRQ: 40%-80%). Men, those with younger age, higher education, incomplete lesions, and non-traumatic etiology showed significantly increased odds of working more hours per week. Significantly more people worked part-time than in the general population with the greatest difference found for males with tetraplegia aged between 40 and 54. LMP of persons with SCI is comparatively high in Switzerland. LMP after SCI is, however, considerably lower than in the general population. Future research needs to show whether the reduced LMP in SCI reflects individual capacity adjustment, contextual constraints on higher LMP or both.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moyer, Bruce A.

The North American industry has employed major solvent-extraction processes to support a wide range of separations including but not limited to chemical, metallurgical, nuclear, biochemical, pharmaceutical, and petroleum applications. The knowledge enabling these separations has been obtained through fundamental studies in academe, government and industry. The International Solvent Extraction Conferences have been and continue to be a major gathering of scientists, engineers, operators, and vendors from around the world, who present new findings since the last meeting, exchange ideas, make business contacts, and conduct collegial discussions. The ISEC 2008 program emphasizes fundamentals to industrial applications of solvent extraction, particularly howmore » this broad spectrum of activities is interconnected and has led to the implementation of novel processes. The oral and poster sessions have been organized into seven topics: Fundamentals; Novel Reagents, Materials and Techniques; Nuclear Fuel Reprocessing; Hydrometallurgy and Metals Extraction; Analytical and Preparative Applications; Biotechnology, Pharmaceuticals, Life-Science Products, and Organic Products; and Process Chemistry and Engineering. Over 350 abstracts were received, resulting in more than 260 manuscripts published in these proceedings. Five outstanding plenary presentations have been identified, with five parallel sessions for oral presentations and posters. In recognition of the major role solvent extraction (SX) plays in the hydrometallurgical and nuclear industries, these proceedings begin with sections focusing on hydrometallurgy, process chemistry, and engineering. More fundamental topics follow, including sections on novel reagents, materials, and techniques, featuring novel applications in analytical and biotechnology areas. Despite the diversity of topics and ideas represented, however, the primary focus of the ISEC community continues to be metals extraction. Four papers from these proceedings have been entered already in INIS in the form of individual reports. Among the remaining papers, 60 have been selected from the following sessions: Plenary Lectures, Hydrometallurgy and Metals Extraction, Nuclear Fuel Reprocessing, Analytical and Preparative Applications, Fundamentals, and Novel Reagents, Materials, and Techniques.« less

MO-B-201-00: Motion Management in Current Stereotactic Body Radiation Therapy (SBRT) Practice

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The motion management in stereotactic body radiation therapy (SBRT) is a key to success for a SBRT program, and still an on-going challenging task. A major factor is that moving structures behave differently than standing structures when examined by imaging modalities, and thus require special considerations and employments. Understanding the motion effects to these different imaging processes is a prerequisite for a decent motion management program. The commonly used motion control techniques to physically restrict tumor motion, if adopted correctly, effectively increase the conformity and accuracy of hypofractionated treatment. The effective application of such requires one to understand the mechanicsmore » of the application and the related physiology especially related to respiration. The image-guided radiation beam control, or tumor tracking, further realized the endeavor for precision-targeting. During tumor tracking, the respiratory motion is often constantly monitored by non-ionizing beam sources using the body surface as its surrogate. This then has to synchronize with the actual internal tumor motion. The latter is often accomplished by stereo X-ray imaging or similar techniques. With these advanced technologies, one may drastically reduce the treated volume and increase the clinicians’ confidence for a high fractional ablative radiation dose. However, the challenges in implementing the motion management may not be trivial and is dependent on each clinic case. This session of presentations is intended to provide an overview of the current techniques used in managing the tumor motion in SBRT, specifically for routine lung SBRT, proton based treatments, and newly-developed MR guided RT. Learning Objectives: Through this presentation, the audience will understand basic roles of commonly used imaging modalities for lung cancer studies; familiarize the major advantages and limitations of each discussed motion control methods; familiarize the major advantages and limitations of each discussed radiation beam control methodology and tumor tacking method; understand the key points in motion management for a high quality SBRT program.« less

MO-B-201-01: Overcoming the Challenges of Motion Management in Current Lung SBRT Practice

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shang, C.

The motion management in stereotactic body radiation therapy (SBRT) is a key to success for a SBRT program, and still an on-going challenging task. A major factor is that moving structures behave differently than standing structures when examined by imaging modalities, and thus require special considerations and employments. Understanding the motion effects to these different imaging processes is a prerequisite for a decent motion management program. The commonly used motion control techniques to physically restrict tumor motion, if adopted correctly, effectively increase the conformity and accuracy of hypofractionated treatment. The effective application of such requires one to understand the mechanicsmore » of the application and the related physiology especially related to respiration. The image-guided radiation beam control, or tumor tracking, further realized the endeavor for precision-targeting. During tumor tracking, the respiratory motion is often constantly monitored by non-ionizing beam sources using the body surface as its surrogate. This then has to synchronize with the actual internal tumor motion. The latter is often accomplished by stereo X-ray imaging or similar techniques. With these advanced technologies, one may drastically reduce the treated volume and increase the clinicians’ confidence for a high fractional ablative radiation dose. However, the challenges in implementing the motion management may not be trivial and is dependent on each clinic case. This session of presentations is intended to provide an overview of the current techniques used in managing the tumor motion in SBRT, specifically for routine lung SBRT, proton based treatments, and newly-developed MR guided RT. Learning Objectives: Through this presentation, the audience will understand basic roles of commonly used imaging modalities for lung cancer studies; familiarize the major advantages and limitations of each discussed motion control methods; familiarize the major advantages and limitations of each discussed radiation beam control methodology and tumor tacking method; understand the key points in motion management for a high quality SBRT program.« less

MO-B-201-02: Motion Management for Proton Lung SBR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Flampouri, S.

The motion management in stereotactic body radiation therapy (SBRT) is a key to success for a SBRT program, and still an on-going challenging task. A major factor is that moving structures behave differently than standing structures when examined by imaging modalities, and thus require special considerations and employments. Understanding the motion effects to these different imaging processes is a prerequisite for a decent motion management program. The commonly used motion control techniques to physically restrict tumor motion, if adopted correctly, effectively increase the conformity and accuracy of hypofractionated treatment. The effective application of such requires one to understand the mechanicsmore » of the application and the related physiology especially related to respiration. The image-guided radiation beam control, or tumor tracking, further realized the endeavor for precision-targeting. During tumor tracking, the respiratory motion is often constantly monitored by non-ionizing beam sources using the body surface as its surrogate. This then has to synchronize with the actual internal tumor motion. The latter is often accomplished by stereo X-ray imaging or similar techniques. With these advanced technologies, one may drastically reduce the treated volume and increase the clinicians’ confidence for a high fractional ablative radiation dose. However, the challenges in implementing the motion management may not be trivial and is dependent on each clinic case. This session of presentations is intended to provide an overview of the current techniques used in managing the tumor motion in SBRT, specifically for routine lung SBRT, proton based treatments, and newly-developed MR guided RT. Learning Objectives: Through this presentation, the audience will understand basic roles of commonly used imaging modalities for lung cancer studies; familiarize the major advantages and limitations of each discussed motion control methods; familiarize the major advantages and limitations of each discussed radiation beam control methodology and tumor tacking method; understand the key points in motion management for a high quality SBRT program.« less

Control Law Design in a Computational Aeroelasticity Environment

NASA Technical Reports Server (NTRS)

Newsom, Jerry R.; Robertshaw, Harry H.; Kapania, Rakesh K.

2003-01-01

A methodology for designing active control laws in a computational aeroelasticity environment is given. The methodology involves employing a systems identification technique to develop an explicit state-space model for control law design from the output of a computational aeroelasticity code. The particular computational aeroelasticity code employed in this paper solves the transonic small disturbance aerodynamic equation using a time-accurate, finite-difference scheme. Linear structural dynamics equations are integrated simultaneously with the computational fluid dynamics equations to determine the time responses of the structure. These structural responses are employed as the input to a modern systems identification technique that determines the Markov parameters of an "equivalent linear system". The Eigensystem Realization Algorithm is then employed to develop an explicit state-space model of the equivalent linear system. The Linear Quadratic Guassian control law design technique is employed to design a control law. The computational aeroelasticity code is modified to accept control laws and perform closed-loop simulations. Flutter control of a rectangular wing model is chosen to demonstrate the methodology. Various cases are used to illustrate the usefulness of the methodology as the nonlinearity of the aeroelastic system is increased through increased angle-of-attack changes.

What Can I Do with a Communication Degree? Four Misconceptions and Some New Questions.

ERIC Educational Resources Information Center

O'Brien, Jill L.

1984-01-01

Those seeking or those who have obtained a communications degree often ask what they can do with their degree. Their quest for universal employment categories uniquely appropriate for communication majors is shaped by four beliefs: (1) content expertise is the primary asset the communication major brings to a potential employer; (2) communication…

Beyond the Parental Leave Debate: The Impact of Laws in Four States.

ERIC Educational Resources Information Center

Bond, James T.; And Others

The State Parental Leave Study, which was conducted by the Families and Work Institute, covered the states of Minnesota, Oregon, Rhode Island, and Wisconsin. It was found that: (1) Implementation of state leave legislation was easy for the vast majority of employers; (2) The majority of employers did not report substantial costs resulting from the…

Education Programs: Major Issues Affecting Postsecondary Education, School-to-Work, and Youth Employment Programs.

ERIC Educational Resources Information Center

General Accounting Office, Washington, DC. Health, Education, and Human Services Div.

This document summarizes major postsecondary education issues and school-to-work and youth employment programs for the Education Task Force of the U.S. Senates's Committee on the Budget, and is based on General Accounting Office (GAO) studies completed during 1990-1997. The discussion of postsecondary education issues centers around five themes:…

Characterizing Factors of Employment Status in Persons With Major Depressive Disorder.

PubMed

Chen, Fang-Pei; Samet, Sharon; Gorroochurn, Prakash; O'Hara, Kathleen M

2016-09-01

Employment is fundamental to mental health recovery. The aim of this study is to construct a parsimonious profile indicating employment potential of people with major depressive disorder (MDD) to facilitate clinical assessment on employment participation. Data were drawn from Waves 1 (2001-2002) and 2 (2004-2005) of the National Epidemiologic Survey on Alcohol and Related Conditions. We included participants who had MDD at Wave 1 and were interviewed in both waves (N = 2,864). We conducted Classification and Regression Tree (CART) analysis to identify key characterizing factors of Wave 2 employment among 32 Wave 1 risk and protective factors. The results show that 82.1% of those employed at Wave 1 were likely to be employed at Wave 2. Among those unemployed at Wave 1, 51% of those motivated to work, measured by work-seeking behavior in the prior year, were likely to be employed at Wave 2. Among those unemployed and motivated to work, better functional mental health was associated with employment (>25.3 vs. ≤25.3). Results highlight the importance of motivation to work, shown in active work seeking, in facilitating employment despite clinical conditions. © The Author(s) 2015.

Computerized detection of unruptured aneurysms in MRA images: reduction of false positives using anatomical location features

NASA Astrophysics Data System (ADS)

Uchiyama, Yoshikazu; Gao, Xin; Hara, Takeshi; Fujita, Hiroshi; Ando, Hiromichi; Yamakawa, Hiroyasu; Asano, Takahiko; Kato, Hiroki; Iwama, Toru; Kanematsu, Masayuki; Hoshi, Hiroaki

2008-03-01

The detection of unruptured aneurysms is a major subject in magnetic resonance angiography (MRA). However, their accurate detection is often difficult because of the overlapping between the aneurysm and the adjacent vessels on maximum intensity projection images. The purpose of this study is to develop a computerized method for the detection of unruptured aneurysms in order to assist radiologists in image interpretation. The vessel regions were first segmented using gray-level thresholding and a region growing technique. The gradient concentration (GC) filter was then employed for the enhancement of the aneurysms. The initial candidates were identified in the GC image using a gray-level threshold. For the elimination of false positives (FPs), we determined shape features and an anatomical location feature. Finally, rule-based schemes and quadratic discriminant analysis were employed along with these features for distinguishing between the aneurysms and the FPs. The sensitivity for the detection of unruptured aneurysms was 90.0% with 1.52 FPs per patient. Our computerized scheme can be useful in assisting the radiologists in the detection of unruptured aneurysms in MRA images.

Recruitment and Retention of Older Adults in Aging Research

PubMed Central

Mody, Lona; Miller, Douglas K.; McGloin, Joanne M.; Div, M; Freeman, Marcie; Marcantonio, Edward R.; Magaziner, Jay; Studenski, Stephanie

2009-01-01

Older adults continue to be underrepresented in clinical research despite their burgeoning population in the United States and worldwide. Physicians often propose treatment plans for older adults based on data from studies involving primarily younger, more-functional, healthier participants. Major barriers to recruitment of older adults in aging research relate to their substantial health problems, social and cultural barriers, and potentially impaired capacity to provide informed consent. Institutionalized older adults offer another layer of complexity that requires cooperation from the institutions to participate in research activities. This paper provides study recruitment and retention techniques and strategies to address concerns and overcome barriers to older adult participation in clinical research. Key approaches include early in-depth planning; minimizing exclusion criteria; securing cooperation from all interested parties; using advisory boards, timely screening, identification, and approach of eligible patients; carefully reviewing the benefit:risk ratio to be sure it is appropriate; and employing strategies to ensure successful retention across the continuum of care. Targeting specific strategies to the condition, site, and population of interest and anticipating potential problems and promptly employing predeveloped contingency plans are keys to effective recruitment and retention. PMID:19093934

System, Apparatus and Method Employing a Dual Head Laser

NASA Technical Reports Server (NTRS)

Coyle, Donald B. (Inventor); Stysley, Paul R. (Inventor); Poulios, Demetrios (Inventor)

2015-01-01

A system, apparatus and method employing a laser with a split-head, V-assembly gain material configuration. Additionally, the present invention is directed to techniques to better dissipate or remove unwanted energies in laser operations. The present invention is also directed to techniques for better collimated laser beams, with single spatial mode quality (TEM00), with improved efficiency, in extreme environments, such as in outer space.

In vivo evaluation of drug delivery after ultrasound application: A new use for the photoacoustic technique

NASA Astrophysics Data System (ADS)

Barja, P. R.; Acosta-Avalos, D.; Rompe, P. C. B.; Dos Anjos, F. H.; Marciano, F. R.; da Silva, M. D.

2005-06-01

Ultrasound application is a therapeutical resource widely employed in physiotherapy. One of its applications is the phonophoresis, a technique in which the ultrasound radiation is utilized to deliver drugs through the skin to soft tissues. The proposal of our study was to employ the Photoacoustic Technique to evaluate the efficacy of such treatment, analyzing if phonophoresis could enhance drug delivery through skin when compared to the more traditional method of manual massage. The configuration of the system employed was such that it was possible to perform in vivo measurements, which is a pre-requisite for this kind of study. The changes observed in the photoacoustic signal amplitude after each form of drug application were attributed to changes in the thermal effusivity of the system, due to penetration of the drug. The technique was able to detect differences in drug delivery between the specified physiotherapy treatments, indicating that phonophoresis enhances drug absorption by tissue.

Monitoring beach changes using GPS surveying techniques

USGS Publications Warehouse

Morton, Robert; Leach, Mark P.; Paine, Jeffrey G.; Cardoza, Michael A.

1993-01-01

The adaptation of Global Positioning System (GPS) surveying techniques to beach monitoring activities is a promising response to this challenge. An experiment that employed both GPS and conventional beach surveying was conducted, and a new beach monitoring method employing kinematic GPS surveys was devised. This new method involves the collection of precise shore-parallel and shore-normal GPS positions from a moving vehicle so that an accurate two-dimensional beach surface can be generated. Results show that the GPS measurements agree with conventional shore-normal surveys at the 1 cm level, and repeated GPS measurements employing the moving vehicle demonstrate a precision of better than 1 cm. In addition, the nearly continuous sampling and increased resolution provided by the GPS surveying technique reveals alongshore changes in beach morphology that are undetected by conventional shore-normal profiles. The application of GPS surveying techniques combined with the refinement of appropriate methods for data collection and analysis provides a better understanding of beach changes, sediment transport, and storm impacts.

Protein-membrane electrostatic interactions: Application of the Lekner summation technique

NASA Astrophysics Data System (ADS)

Juffer, André H.; Shepherd, Craig M.; Vogel, Hans J.

2001-01-01

A model has been developed to calculate the electrostatic interaction between biomolecules and lipid bilayers. The effect of ionic strength is included by means of explicit ions, while water is described as a background continuum. The bilayer is considered at the atomic level. The Lekner summation technique is employed to calculate the long-range electrostatic interactions. The new method is employed to estimate the electrostatic contribution to the free energy of binding of sandostatin, a cyclic eight-residue analogue of the peptide hormone somatostatin, to lipid bilayers with thermodynamic integration. Monte Carlo simulation techniques were employed to determine ion distributions and peptide orientations. Both neutral as well as negatively charged lipid bilayers were used. An error analysis to judge the quality of the computation is also presented. The applicability of the Lekner summation technique to combine it with computer simulation models that simulate the adsorption of peptides (and proteins) into the interfacial region of lipid bilayers is discussed.

Zinc-finger nucleases-based genome engineering to generate isogenic human cell lines.

PubMed

Dreyer, Anne-Kathrin; Cathomen, Toni

2012-01-01

Customized zinc-finger nucleases (ZFNs) have developed into a promising technology to precisely alter mammalian genomes for biomedical research, biotechnology, or human gene therapy. In the context of synthetic biology, the targeted integration of a transgene or reporter cassette into a "neutral site" of the human genome, such as the AAVS1 locus, permits the generation of isogenic human cell lines with two major advantages over standard genetic manipulation techniques: minimal integration site-dependent effects on the transgene and, vice versa, no functional perturbation of the host-cell transcriptome. Here we describe in detail how ZFNs can be employed to target integration of a transgene cassette into the AAVS1 locus and how to characterize the targeted cells by PCR-based genotyping.

GPS-based satellite tracking system for precise positioning

NASA Technical Reports Server (NTRS)

Yunck, T. P.; Melbourne, W. G.; Thornton, C. L.

1985-01-01

NASA is developing a Global Positioning System (GPS) based measurement system to provide precise determination of earth satellite orbits, geodetic baselines, ionospheric electron content, and clock offsets between worldwide tracking sites. The system will employ variations on the differential GPS observing technique and will use a network of nine fixed ground terminals. Satellite applications will require either a GPS flight receiver or an on-board GPS beacon. Operation of the system for all but satellite tracking will begin by 1988. The first major satellite application will be a demonstration of decimeter accuracy in determining the altitude of TOPEX in the early 1990's. By then the system is expected to yield long-baseline accuracies of a few centimeters and instantaneous time synchronization to 1 ns.

PATHOPHYSIOLOGICAN AND CLINICAL ASSESSMENT OF CHANGES OF ERYTHROCYTE RESISTANCE TO SAPONIN IN THE PROCESS OF ROENTGEN THERAPY (in Russian)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krylov, A.A.

1961-04-01

In 40 patients undergoing roentgen therapy dynamic studies were made concerning the resistance of erythrocytes to saponin. A method of kinelysis was employed with a Soviet photoelectric colorimeter FEK-M. In the majority of patients subject to deep roentgen therapy there was noted a considerable rise of erythrocyte resistance to saponin, which is considered as a manifestation of compensatory mechanisms. A rapid decline of the resistance ("saponin disruption'') was preceded, as a ruls, by radiation toxemia and served as a signal of the necessity of repeated blood transfusions. The technique referred to is recommended as an objective index of the statemore » of regulatory mechanisms in the process of irradiation. (auth)« less

Fibrinolysis and Beyond: Bridging the Gap between Local and Systemic Clot Removal

PubMed Central

Knauer, K.; Huber, Roman

2011-01-01

Recanalization methods in ischemic stroke have been progressively expanded over the past years. In addition the continuous development of specialized mechanical devices for thrombectomy a broad spectrum of new drugs has been tested: Both options, novel drugs as well as new devices, can be employed independently of each other, but in most cases a combination of the two with the standard treatment of intravenous fibrinolysis is applied. Until recently, a large number of case series have been performed to investigate the effects of various drugs and interventions, but only a few trials have been conducted to determine the optimal conditions for combining both procedures. This review surveys the different systemic and endovascular vessel reopening practices and their major bridging techniques. PMID:21373206

Are stock market returns related to the weather effects? Empirical evidence from Taiwan

NASA Astrophysics Data System (ADS)

Chang, Tsangyao; Nieh, Chien-Chung; Yang, Ming Jing; Yang, Tse-Yu

2006-05-01

In this study, we employ a recently developed econometric technique of the threshold model with the GJR-GARCH process on error terms to investigate the relationships between weather factors and stock market returns in Taiwan using daily data for the period of 1 July 1997-22 October 2003. The major weather factors studied include temperature, humidity, and cloud cover. Our empirical evidence shows that temperature and cloud cover are two important weather factors that affect the stock returns in Taiwan. Our empirical findings further support the previous arguments that advocate the inclusion of economically neutral behavioral variables in asset pricing models. These results also have significant implications for individual investors and financial institutions planning to invest in the Taiwan stock market.

Determination of carrier lifetime and mobility in colloidal quantum dot films via impedance spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rath, Arup K.; Lasanta, Tania; Bernechea, Maria

2014-02-10

Impedance Spectroscopy (IS) proves to be a powerful tool for the determination of carrier lifetime and majority carrier mobility in colloidal quantum dot films. We employ IS to determine the carrier lifetime in PbS quantum dot Schottky solar cells with Al and we verify the validity of the technique via transient photovoltage. We also present a simple approach based on an RC model that allows the determination of carrier mobility in PbS quantum dot films and we corroborate the results via comparison with space charge limited measurements. In summary, we demonstrate the potential of IS to characterize key-to-photovoltaics optoelectronic properties,more » carrier lifetime, and mobility, in a facile way.« less

FTMP - A highly reliable Fault-Tolerant Multiprocessor for aircraft

NASA Technical Reports Server (NTRS)

Hopkins, A. L., Jr.; Smith, T. B., III; Lala, J. H.

1978-01-01

The FTMP (Fault-Tolerant Multiprocessor) is a complex multiprocessor computer that employs a form of redundancy related to systems considered by Mathur (1971), in which each major module can substitute for any other module of the same type. Despite the conceptual simplicity of the redundancy form, the implementation has many intricacies owing partly to the low target failure rate, and partly to the difficulty of eliminating single-fault vulnerability. An extensive analysis of the computer through the use of such modeling techniques as Markov processes and combinatorial mathematics shows that for random hard faults the computer can meet its requirements. It is also shown that the maintenance scheduled at intervals of 200 hr or more can be adequate most of the time.

Mass Movement Susceptibility Mapping Using Satellite Optical Imagery Compared With INSAR Monitoring: Zigui County, Three Gorges Region, China

NASA Astrophysics Data System (ADS)

Kincal, Cem; Singleton, Andrew; Liu, Peng; Li, Zhenhong; Drummond, Jane; Hoey, Trevor; Muller, Jan-Peter; Qu, Wei; Zeng, Qiming; Zhang, Jingfa; Du, Peijun

2010-10-01

Mass movements on steep slopes are a major hazard to communities and infrastructure in the Three Gorges region, China. Developing susceptibility maps of mass movements is therefore very important in both current and future land use planning. This study employed satellite optical imagery and an ASTER GDEM (15 m) to derive various parameters (namely geology; slope gradient; proximity to drainage networks and proximity to lineaments) in order to create a GIS-based map of mass movement susceptibility. This map was then evaluated using highly accurate deformation signals processed using the Persistent Scatterer (PS) InSAR technique. Areas of high susceptibility correspond well to points of high subsidence, which provides a strong support of our susceptibility map.

Controlling the light shift of the CPT resonance by modulation technique

NASA Astrophysics Data System (ADS)

Tsygankov, E. A.; Petropavlovsky, S. V.; Vaskovskaya, M. I.; Zibrov, S. A.; Velichansky, V. L.; Yakovlev, V. P.

2017-12-01

Motivated by recent developments in atomic frequency standards employing the effect of coherent population trapping (CPT), we propose a theoretical framework for the frequency modulation spectroscopy of the CPT resonances. Under realistic assumptions we provide simple yet non-trivial analytical formulae for the major spectroscopic signals such as the CPT resonance line and the in-phase/quadrature responses. We discuss the influence of the light shift and, in particular, derive a simple expression for the displacement of the resonance as a function of modulation index. The performance of the model is checked against numerical simulations, the agreement is good to perfect. The obtained results can be used in more general models accounting for light absorption in the thick optical medium.

Effect of PbO on optical properties of tellurite glass

NASA Astrophysics Data System (ADS)

Elazoumi, S. H.; Sidek, H. A. A.; Rammah, Y. S.; El-Mallawany, R.; Halimah, M. K.; Matori, K. A.; Zaid, M. H. M.

2018-03-01

Binary (1 - x)(TeO2) - x(PbO), x = 0, 0.10, 0.15, 0.20, 0.25, 0.30 mol% glass system was fabricated using melt quenching method. X-ray diffraction (XRD) technique was employed to confirm the amorphous nature. The microanalysis of the major components was performed using energy dispersive EDX and X-ray spectrometry. Both the molar volume and the density were measured. FTIR and UV spectra were recorded at 400-4000 cm-1 and 220-800 nm, respectively. The optical band gap (Eopt), Urbach's energy (Eu), index of refraction (n) were calculated using absorption spectrum fitting (ASF) and derivation of absorption spectrum fitting (DASF) methods. Molar refraction Rm and molecular polarizability αm have been calculated according to (ASF) method.

Autonomous Scanning Probe Microscopy in Situ Tip Conditioning through Machine Learning.

PubMed

Rashidi, Mohammad; Wolkow, Robert A

2018-05-23

Atomic-scale characterization and manipulation with scanning probe microscopy rely upon the use of an atomically sharp probe. Here we present automated methods based on machine learning to automatically detect and recondition the quality of the probe of a scanning tunneling microscope. As a model system, we employ these techniques on the technologically relevant hydrogen-terminated silicon surface, training the network to recognize abnormalities in the appearance of surface dangling bonds. Of the machine learning methods tested, a convolutional neural network yielded the greatest accuracy, achieving a positive identification of degraded tips in 97% of the test cases. By using multiple points of comparison and majority voting, the accuracy of the method is improved beyond 99%.

Employer Preferences for Resumes and Cover Letters

ERIC Educational Resources Information Center

Schullery, Nancy M.; Ickes, Linda; Schullery, Stephen E.

2009-01-01

This article reports the results of a survey of employers' preferences for resume style, resume delivery method, and cover letters. Employers still widely prefer the standard chronological resume, with only 3% desiring a scannable resume. The vast majority of employers prefer electronic delivery, either by email (46%) or at the company's Web site…

Analysis of Employment Flow of Landscape Architecture Graduates in Agricultural Universities

ERIC Educational Resources Information Center

Yao, Xia; He, Linchun

2012-01-01

A statistical analysis of employment flow of landscape architecture graduates was conducted on the employment data of graduates major in landscape architecture in 2008 to 2011. The employment flow of graduates was to be admitted to graduate students, industrial direction and regional distribution, etc. Then, the features of talent flow and factors…

Efficient and anonymous two-factor user authentication in wireless sensor networks: achieving user anonymity with lightweight sensor computation.

PubMed

Nam, Junghyun; Choo, Kim-Kwang Raymond; Han, Sangchul; Kim, Moonseong; Paik, Juryon; Won, Dongho

2015-01-01

A smart-card-based user authentication scheme for wireless sensor networks (hereafter referred to as a SCA-WSN scheme) is designed to ensure that only users who possess both a smart card and the corresponding password are allowed to gain access to sensor data and their transmissions. Despite many research efforts in recent years, it remains a challenging task to design an efficient SCA-WSN scheme that achieves user anonymity. The majority of published SCA-WSN schemes use only lightweight cryptographic techniques (rather than public-key cryptographic techniques) for the sake of efficiency, and have been demonstrated to suffer from the inability to provide user anonymity. Some schemes employ elliptic curve cryptography for better security but require sensors with strict resource constraints to perform computationally expensive scalar-point multiplications; despite the increased computational requirements, these schemes do not provide user anonymity. In this paper, we present a new SCA-WSN scheme that not only achieves user anonymity but also is efficient in terms of the computation loads for sensors. Our scheme employs elliptic curve cryptography but restricts its use only to anonymous user-to-gateway authentication, thereby allowing sensors to perform only lightweight cryptographic operations. Our scheme also enjoys provable security in a formal model extended from the widely accepted Bellare-Pointcheval-Rogaway (2000) model to capture the user anonymity property and various SCA-WSN specific attacks (e.g., stolen smart card attacks, node capture attacks, privileged insider attacks, and stolen verifier attacks).

Efficient and Anonymous Two-Factor User Authentication in Wireless Sensor Networks: Achieving User Anonymity with Lightweight Sensor Computation

PubMed Central

Nam, Junghyun; Choo, Kim-Kwang Raymond; Han, Sangchul; Kim, Moonseong; Paik, Juryon; Won, Dongho

2015-01-01

A smart-card-based user authentication scheme for wireless sensor networks (hereafter referred to as a SCA-WSN scheme) is designed to ensure that only users who possess both a smart card and the corresponding password are allowed to gain access to sensor data and their transmissions. Despite many research efforts in recent years, it remains a challenging task to design an efficient SCA-WSN scheme that achieves user anonymity. The majority of published SCA-WSN schemes use only lightweight cryptographic techniques (rather than public-key cryptographic techniques) for the sake of efficiency, and have been demonstrated to suffer from the inability to provide user anonymity. Some schemes employ elliptic curve cryptography for better security but require sensors with strict resource constraints to perform computationally expensive scalar-point multiplications; despite the increased computational requirements, these schemes do not provide user anonymity. In this paper, we present a new SCA-WSN scheme that not only achieves user anonymity but also is efficient in terms of the computation loads for sensors. Our scheme employs elliptic curve cryptography but restricts its use only to anonymous user-to-gateway authentication, thereby allowing sensors to perform only lightweight cryptographic operations. Our scheme also enjoys provable security in a formal model extended from the widely accepted Bellare-Pointcheval-Rogaway (2000) model to capture the user anonymity property and various SCA-WSN specific attacks (e.g., stolen smart card attacks, node capture attacks, privileged insider attacks, and stolen verifier attacks). PMID:25849359

Experiment K-7-18: Effects of Spaceflight in the Muscle Adductor Longus of Rats Flown in the Soviet Biosatellite Cosmos 2044. Part 1; A Study Employing Neural Cell Adhesion Molecules (N-CAM) Immunocytochemistry and Conventional Morphological Techniques (Light and Electron Microscopy)

NASA Technical Reports Server (NTRS)

Daunton, N. G.; DAmelio, F.; Wu, L.; Ilyina-Kakueva, E. I.; Krasnov, I. B.; Hyde, T. M.; Sigworth, S. K.

1994-01-01

The effects of spaceflight upon the 'slow' muscle adductor longus was examined in rats flown in the Soviet Biosatellite COSMOS 2044. Three groups - synchronous, vivarium and basal served as controls. The techniques employed included standard methods for light microscopy, N-CAM immunocytochemistry and electron microscopy. Light microscopic observations revealed myofiber atrophy, contraction bands and segmental necrosis accompanied by cellular infiltrates composed of macrophages, leucocytes and mononuclear cells. N-CAM immunoreactivity was seen (N-CAM-IR) on the myofiber surface, satellite cells and in regenerating myofibers reminiscent of myotubes. Ultrastructural alterations included Z band streaming, disorganization of myofibrillar architecture, sarcoplasmic degradation, extensive segmental necrosis with preservation of the basement membrane, degenerative phenomena of the capillary endothelium and cellular invasion of necrotic areas. Regenerating myofibers were identified by the presence of increased amounts of ribosomal aggregates and chains of polyribosomes associated with myofilaments that displayed varied distributive patterns. The principal electron microscopic changes of the neuromuscular junctions consisted of a decrease or absence of synaptic vesicles, degeneration of axon terminals, increased number of microtubules, vacant axonal spaces and axonal sprouting. The present observations indicate that major alterations such as myofibrillar disruption and necrosis, muscle regeneration and denervation and synaptic remodeling at the level of the neuromuscular junction may take place during spaceflight.

Increased anterior default-mode network homogeneity in first-episode, drug-naive major depressive disorder: A replication study.

PubMed

Guo, Wenbin; Cui, Xilong; Liu, Feng; Chen, Jindong; Xie, Guangrong; Wu, Renrong; Zhang, Zhikun; Chen, Huafu; Zhao, Jingping

2018-01-01

Abnormal default-mode network (DMN) homogeneity has been involved in the neurophysiology of major depressive disorder (MDD) with inconsistent findings. The inconsistency may be due to clinical and methodological variability, and the reproducibility of the findings is limited. The present study aimed to examine alterations of the DMN homogeneity in two independent samples of patients with first-episode, drug-naive MDD. The samples included 59 patients with MDD and 31 comparison subjects from Sample 1 and 29 patients with MDD and 24 comparison subjects from Sample 2. Network homogeneity (NH) was computed with an overlapping technique, which was employed to define brain regions with abnormal NH common to the MDD samples. Compared with comparison subjects, patients with MDD exhibited increased NH in an overlapped brain region of the left superior medial prefrontal cortex (MPFC). No correlations were found between abnormal NH and HAMD total/subscale scores in the patients of each sample and in the combined patients from both samples. This study is the first to examine alterations of DMN homogeneity in first-episode, drug-naive patients with MDD in two independent samples by using an overlapping technique. Patients with MDD exhibit increased NH in an overlapped region in the anterior DMN. The present study thus highlights the importance of the DMN in the neurophysiology of MDD. Copyright © 2017 Elsevier B.V. All rights reserved.

Mathematic in science progress reort, June 1, 1973-May 31, 1974

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bellman, R.

1974-01-01

The purpose of the matematical biosciences group is to use the conceptual, analytic and computational methods of modern mathematics to treat biomedical and environmental problems. We are employing a systems approach to research, beginning with experiment and medical practice at one end of the scale, continuing through the intermediary of mathematical models and computer techniques, and culminating in clinical applications working closely with teams of doctors. We are pursuing the application of biostatistical methods to a number of medical questions as well as a thoroughgoing use of operations research and systems analysis to hospital practice. The overall objective is tomore » make the Medicare program operational, effective as well as cheap. Pattern recognition and other aspects of artificial intelligence are important here for patient screening. Major efforts are devoted to nuclear medicine, radiotherapy and neurophysiology using the mathematical theory of control and decision processes (dynamic programming and invarient imbedding). Important savings have been made in the time required for tumor scanning using techniques of nuclear medicine. Major mathematical breakthroughs have been made in the treatment of large scale systems, and parameter identification processes. In the field of mental health, we have developed and extended the computerized simulation processes using graphics which are versatile tools for research and training in human interaction processes, particularly in the initial psychotherapy interview.« less

3D-Printing: an emerging and a revolutionary technology in pharmaceuticals.

PubMed

Singhvi, Gautam; Patil, Shalini; Girdhar, Vishal; Chellappan, Dinesh K; Gupta, Gaurav; Dua, Kamal

2018-06-01

One of the novel and progressive technology employed in pharmaceutical manufacturing, design of medical device and tissue engineering is threedimensional (3D) printing. 3D printing technologies provide great advantages in 3D scaffolds fabrication over traditional methods in the control of pore size, porosity, and interconnectivity. Various techniques of 3Dprinting include powder bed fusion, fused deposition modeling, binder deposition, inkjet printing, photopolymerization and many others which are still evolving. 3Dprinting technique been employed in developing immediate release products, various systems to deliver multiple release modalities etc. 3D printing has opened the door for new generation of customized drug delivery with builtin flexibility for safer and effective therapy. Our minireview provides a quick snapshot on an overview of 3D printing, various techniques employed, applications and its advancements in pharmaceutical sciences.

Assessing the nonlinear response of fine particles to precursor emissions: Development and application of an extended response surface modeling technique v1.0

DOE PAGES

Zhao, B.; Wang, S. X.; Xing, J.; ...

2015-01-30

An innovative extended response surface modeling technique (ERSM v1.0) is developed to characterize the nonlinear response of fine particles (PM₂̣₅) to large and simultaneous changes of multiple precursor emissions from multiple regions and sectors. The ERSM technique is developed based on the conventional response surface modeling (RSM) technique; it first quantifies the relationship between PM₂̣₅ concentrations and the emissions of gaseous precursors from each single region using the conventional RSM technique, and then assesses the effects of inter-regional transport of PM₂̣₅ and its gaseous precursors on PM₂̣₅ concentrations in the target region. We apply this novel technique with a widelymore » used regional chemical transport model (CTM) over the Yangtze River delta (YRD) region of China, and evaluate the response of PM₂̣₅ and its inorganic components to the emissions of 36 pollutant–region–sector combinations. The predicted PM₂̣₅ concentrations agree well with independent CTM simulations; the correlation coefficients are larger than 0.98 and 0.99, and the mean normalized errors (MNEs) are less than 1 and 2% for January and August, respectively. It is also demonstrated that the ERSM technique could reproduce fairly well the response of PM₂̣₅ to continuous changes of precursor emission levels between zero and 150%. Employing this new technique, we identify the major sources contributing to PM₂̣₅ and its inorganic components in the YRD region. The nonlinearity in the response of PM₂̣₅ to emission changes is characterized and the underlying chemical processes are illustrated.« less

75 FR 39621 - Proposed Information Collection (Income-Net Worth and Employment Statement) Activity: Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-09

... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-0002] Proposed Information Collection (Income-Net Worth and Employment Statement) Activity: Comment Request AGENCY: Veterans Benefits Administration... techniques or the use of other forms of information technology. Title: Income-Net Worth and Employment...

Public Education: A Major American Growth Industry in the 1990's.

ERIC Educational Resources Information Center

Ehrenhalt, Samuel M.

Public education has been a major growth industry in the 1990s, expanding its employment by nearly 24 percent from 1988 to 1998. The 1.8 million jobs added in state and local government education functions placed this sector third among America's growth industries in the sheer magnitude of its employment rise. This report examines the record of…

Tactics Employed and Problems Encountered by University English Majors in Hong Kong in Using a Dictionary

ERIC Educational Resources Information Center

Chan, Alice Yin Wa

2005-01-01

Building on the results of a small-scale survey which investigated the general use of dictionaries by university English majors in Hong Kong using a questionnaire survey and their specific use of dictionaries using an error correction task, this article discusses the tactics these students employed and the problems they encountered when using a…

A matrix equation solution by an optimization technique

NASA Technical Reports Server (NTRS)

Johnson, M. J.; Mittra, R.

1972-01-01

The computer solution of matrix equations is often difficult to accomplish due to an ill-conditioned matrix or high noise levels. Two methods of solution are compared for matrices of various degrees of ill-conditioning and for various noise levels in the right hand side vector. One method employs the usual Gaussian elimination. The other solves the equation by an optimization technique and employs a function minimization subroutine.

Pilot survey of NICU nurses' interest in the neonatal nurse practitioner role.

PubMed

Rasmussen, Lynn B; Vargo, Lyn E; Reavey, Daphne A; Hunter, Kim S

2005-02-01

This descriptive, qualitative pilot study explored the interest and perceptions of neonatal intensive care unit (NICU) nurses regarding the neonatal nurse practitioner (NNP) role. Motivating factors to become an NNP, challenges facing NNPs, and rewards of the NNP role from the perspectives of NICU nurses were explored. The convenience sample was obtained using 2 survey techniques. The first sample group included nurses who were employed in Level III NICUs located within 2 major Midwestern cities. In order to confirm the data and to expand the scope, the second sample group was recruited from NICU nurses who were attending a regional educational conference. All participants were currently employed NICU nurses and were therefore potential NNP students. Combining the participants of both enrollment techniques resulted in a potential of 696 subjects. A simple self-administered survey was used to collect data. Narrative data were qualitatively analyzed. Demographic data and categorical items were quantified. This study achieved a total 30% response rate (n = 209). Of the total participants, only 32% of Level III NICU nurses were interested in becoming an NNP. Analysis of the data revealed 6 major categories (themes) of reasons why nurses were not interested in the NNP role. The themes most often mentioned by the participants were (1) obligations to family and/or work (46%) and (2) too much responsibility in the NNP role (30%). The data also revealed several different rewards and challenges for those in the NNP role as well as factors that may motivate nurses to become an NNP. Given the current NNP shortage, an increase in the supply of NNPs for the workforce is imperative. Current enrollment in NNP academic programs does not appear to be meeting the demand. Exploring the factors that influence enrollment in NNP programs from the perspective of potential NNP students is the first step towards increasing the supply of NNPs. The majority of participants were not interested in becoming an NNP for a variety of reasons. Negative perceptions of the NNP role were identified. Solutions posed from these results may provide scientifically sound solutions to help ease the shortage of NNPs. The findings of this naturalistic inquiry may be used to develop an instrument to measure interest in the NNP role.

Large area silicon sheet by EFG. [Edge-defined Film-fed Growth

NASA Technical Reports Server (NTRS)

Rao, C. V. H.; Surek, T.; Mackintosh, B.; Ravi, K. V.; Wald, F. V.

1978-01-01

The edge-defined, film-fed growth (EFG) technique has been employed to grow silicon ribbons for photovoltaic applications. Considerable progress has been made in recent years in developing the technique to the point that long lengths of silicon ribbon can be routinely grown. In order to attain the full low-cost potential of the EFG technique, several further developments such as the growth of thinner and wider ribbons, increase in ribbon growth rate, and improvements in material quality are needed. The technological problems to be solved and the approaches employed to achieve these goals are discussed.

75 FR 61251 - Proposed Information Collection (Request for Employment Information in Connection With Claim for...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-04

... (Request for Employment Information in Connection With Claim for Disability Benefits) Activity: Comment... needed to determine a claimant's eligibility for increased disability benefits. DATES: Written comments... techniques or the use of other forms of information technology. Title: Request for Employment Information in...

78 FR 34175 - Proposed Information Collection (Request for Employment Information in Connection With Claim for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-06

... (Request for Employment Information in Connection With Claim for Disability Benefits) Activity: Comment... needed to determine a claimant's eligibility for increased disability benefits. DATES: Written comments... techniques or the use of other forms of information technology. Title: Request for Employment Information in...

Curriculum Design and Evaluation: An Employer-Centered Action Approach. AIR Forum 1980 Paper.

ERIC Educational Resources Information Center

Mehallis, Mantha Vlahos

The development and validation of an employer-centered action system for curriculum development and evaluation are described. The system used a descriptive/action research design whereby a research team interviewed all major employers in Broward County Florida in a two-year period. Results of an employer needs assessment and task analyses were…

The Effect of Postsecondary Education on Employment and Income for Individuals with Intellectual Disabilities

ERIC Educational Resources Information Center

Sannicandro, Tom

2016-01-01

The low employment rates of individuals with intellectual disabilities (ID) are a major concern. In 2011 only 34% of adults with ID were employed compared to 76% of adults without disabilities (Siperstein, Parker, & Drascher, 2013). Higher educational attainment is associated with higher employment rates for students with ID (Smith, Grigal,…

Benchmarking of state-of-the-art needle detection algorithms in 3D ultrasound data volumes

NASA Astrophysics Data System (ADS)

Pourtaherian, Arash; Zinger, Svitlana; de With, Peter H. N.; Korsten, Hendrikus H. M.; Mihajlovic, Nenad

2015-03-01

Ultrasound-guided needle interventions are widely practiced in medical diagnostics and therapy, i.e. for biopsy guidance, regional anesthesia or for brachytherapy. Needle guidance using 2D ultrasound can be very challenging due to the poor needle visibility and the limited field of view. Since 3D ultrasound transducers are becoming more widely used, needle guidance can be improved and simplified with appropriate computer-aided analyses. In this paper, we compare two state-of-the-art 3D needle detection techniques: a technique based on line filtering from literature and a system employing Gabor transformation. Both algorithms utilize supervised classification to pre-select candidate needle voxels in the volume and then fit a model of the needle on the selected voxels. The major differences between the two approaches are in extracting the feature vectors for classification and selecting the criterion for fitting. We evaluate the performance of the two techniques using manually-annotated ground truth in several ex-vivo situations of different complexities, containing three different needle types with various insertion angles. This extensive evaluation provides better understanding on the limitations and advantages of each technique under different acquisition conditions, which is leading to the development of improved techniques for more reliable and accurate localization. Benchmarking results that the Gabor features are better capable of distinguishing the needle voxels in all datasets. Moreover, it is shown that the complete processing chain of the Gabor-based method outperforms the line filtering in accuracy and stability of the detection results.

Technical and Soft Skills Expectations During the Transition from Recent Graduate to New Hire

NASA Astrophysics Data System (ADS)

Keane, C. M.

2001-12-01

Employer-applicant skill compatibility represents a major component of the career development process, particularly for new entrants to the job market. Newly minted geoscientists largely bring a distinct set of skills learned during their formal education and training, which combined with a broader view of the person are evaluated for career potential in today's major employers. University departments possess a strong view of their role in educating future geoscientists, including the skill sets imparted, the basis of education provided, and the expectation for how their students will evolve into colleagues in the profession. Regretfully, based on numerous surveys by both the American Geological Institute's Human Resources program and other independent studies, the formally transferred skills and expectations do not necessarily match those of many geoscience employers. While academia has increased its focus on increasing technical skills and greater specialization, most geoscience employers have further increased the technology gap between themselves and academia, leading most employers to seek broadly trained and well-educated graduates. Additionally, soft skills represent an area of major disagreement between what is considered important and what is considered feasible in a formal education. While debate continues both within industry and academia over the ideal set of soft skills, the great variance in soft skill demands lead to better opportunities for matching of graduate to employer. This debate further enhances the ongoing discussion of the role of the university, the importance of employer needs, and the health of the geoscience discipline within society. Fundamentally, the hiring and career development process remains as sequence of compromises for both the employer and the recent graduate.

Using Medical-Device Wearable to Improve Hemodialysis Patient’s Live and Access the Holistic Health

NASA Astrophysics Data System (ADS)

Chen, W. L.; Wu, C.-C.; Kan, C. D.

2017-06-01

The increasing incidence of end-stage renal disease (ESRD) is the major burden to health budgets and a threat to public health worldwide. For many years, Taiwan has been ranked the first in the world for the number of hemodialysis patients. For solving the above-mentioned circumstance, we demonstrate the project, here, which goal is to construct the holistic health for hemodialysis patient. The project is to design a wearable medicine-device which can simultaneously measure and monitor the vital sign, including heart rate (HR), pulse oximetry (SPO2), continuous non-invasive blood pressure (c-NIBP), and total body water (TBW), of hemodialysis patient. By aid of the device we design, hemodialysis patients will get better health care than before. This device comprises three techniques. The first is named “Using phonoangiography technique to early detect the dysfunction of arteriovenous access by arteriovenous access (AVA) stenosis detector”. The stenosis detector based on autoregressive model was employed to simultaneously estimate the status of AVA life cycle and to tract changes in frequency spectra. It helps hemodialysis patients to early detect the dysfunction of AVA and alarms them to make a return visit. The second technique is named “Physiological detecting device for wearable medical device and encoding algorithm development”. The feature of the second technique is to optimize the prognosis by analyzing physiological signals, including water content index, pulse oximetry, and blood pressure in the meanwhile. The third technique is named “Intelligent and smart tourniquet”. This technique aims to preclude AVA dysfunction caused by inappropriate hemostasis.

Language Learning Strategies Employed by Chinese English-Major Pre-Service Teachers in Relation to Gender and Personality Types

ERIC Educational Resources Information Center

Zhou, Chaoying; Intaraprasert, Channarong

2015-01-01

This study was intended to investigate the use of language learning strategy employed by English-major pre-service teachers in Midwest China in relation to their gender and personality types. The modified Strategy Inventory for Language Learning (SILL) and adopted personality type inventory were used to collect the data. ANOVA and Chi-square tests…

The Well-Being of Children in Working Poor and Other Families: 1997 and 2004. Child Trends Research Brief. Publication #2008-33

ERIC Educational Resources Information Center

Wertheimer, Richard; Moore, Kristin Anderson; Burkhauser, Mary

2008-01-01

When Congress reformed the welfare system in 1996, major goals of the legislation were to increase employment and income of needy families and to decrease child poverty. Another major goal was to improve child outcomes through increased parental employment and earnings along with other provisions of welfare reform. However, there was also concern…

Individual Placement And Support Services Boost Employment For People With Serious Mental Illnesses, But Funding Is Lacking.

PubMed

Drake, Robert E; Bond, Gary R; Goldman, Howard H; Hogan, Michael F; Karakus, Mustafa

2016-06-01

The majority of people with serious mental illnesses want to work. Individual placement and support services, an evidence-based supported employment intervention, enables about 60 percent of people with serious mental illnesses who receive the services to gain competitive employment and improve their lives, but the approach does not lead to fewer people on government-funded disability rolls. Yet individual placement and support employment services are still unavailable to a large majority of people with serious mental illnesses in the United States. Disability policies and lack of a simple funding mechanism remain the chief barriers. A recent federal emphasis on early-intervention programs may increase access to employment services for people with early psychosis, but whether these interventions will prevent disability over time is unknown. Project HOPE—The People-to-People Health Foundation, Inc.

Development and evaluation of a gas chromatographic method for the determination of triazine herbicides in natural water samples

USGS Publications Warehouse

Steinheimer, T.R.; Brooks, M.G.

1984-01-01

A multi-residue method is described for the determination of triazine herbicides in natural water samples. The technique uses solvent extraction followed by gas chromatographic separation and detection employing nitrogen-selective devices. Seven compounds can be determined simultaneously at a nominal detection limit of 0.1 ??g/L in a 1-litre sample. Three different natural water samples were used for error analysis via evaluation of recovery efficiencies and estimation of overall method precision. As an alternative to liquid-liquid partition (solvent extraction) for removal of compounds of interest from water, solid-phase extraction (SPE) techniques employing chromatographic grade silicas with chemically modified surfaces have been examined. SPE is found to provide rapid and efficient concentration with quantitative recovery of some triazine herbicides from natural water samples. Concentration factors of 500 to 1000 times are obtained readily by the SPE technique.A multi-residue method is described for the determination of triazine herbicides in natural water samples. The technique uses solvent extraction followed by gas chromatographic separation and detection employing nitrogen-selective devices. Seven compounds can be determined simultaneously at a nominal detection limit of 0. 1 mu g/L in a 1-litre sample. As an alternative to liquid-liquid partition (solvent extraction) for removal of compounds of interest from water, solid-phase extraction (SPE) techniques employing chromatographic grade silicas with chemically modified surfaces have been examined. SPE is found to provide rapid and efficient concentration with quantitative recovery of some triazine herbicides from natural water samples. Concentration factors of 500 to 1000 times are obtained readily by the SPE technique.

Implementing metal detector technology and a navigation system in the removal of shrapnel.

PubMed

Peleg, Eran; Harari, Meytal; Liebergall, Meir; Mosheiff, Rami

2009-01-01

The removal of metal shrapnel in the sub-acute phase of casualty treatment requires the utmost accuracy in detection and removal, especially when there is proximity to major neurovascular structures. Inability to successfully locate and remove retained fragments may lead to a variety of complications due to fragment migration. In this study we prove the feasibility of a new technique which uses metal detector technology combined with a surgical navigation system, resulting in improved accuracy and decreased operating time. In each of the experiments, 6 metal nuts were inserted into a dummy leg to simulate shrapnel wounds. Two major experiments were then conducted. Experiment 1 was a comparison of two methods: (a) localization of the nuts using surgical navigation alone, and (b) localization by means of metal detector technology combined with a surgical navigation system (StealthStation® TREON® plus). Experiment 2 employed the same two methods, but this time migration of the metal fragments was introduced. The localization time was measured from incision of the dummy skin to the moment the metal fragment was touched by the searching device. In experiment 1 the results showed no significant differences between the two approaches. In experiment 2 the new technique was found to significantly decrease the mean fragment localization time, taking 9.6 seconds (±7.2 seconds) as compared to 26.4 seconds (±13.8 seconds) when using the regular technique. Combining a metal detector probe and a surgical navigation system was found to significantly decrease operating time and increase the surgeon's confidence, especially in cases where migration of the metal fragment occurred during searching and extraction.

Phlebotomus papatasi and Meriones libycus as the vector and reservoir host of cutaneous leishmaniasis in Qomrood District, Qom Province, central Iran.

PubMed

Yavar, Rassi; Abedin, Saghafipour; Reza, Abai Mohammad; Ali, Oshaghi Mohammad; Sina, Rafizadeh; Mehdi, Mohebail; Reza, Yaaghobi-Ershadi Mohammad; Fatemeh, Mohtarami; Babak, Farzinnia

2011-02-01

To determine the sand flies species responsible for most transmission of Leishmania major (L. major) to human, as well as to determine the main reservoir hosts of the disease. Sand flies were collected using sticky papers and mounted in Puri's medium for species identification. Rodents were trapped by live Sherman traps. Both sand flies and rodents were subjected to molecular methods for detection of leishmanial parasite. Phlebotomus papatasi (P. papatasi) was the common species in outdoor and indoor resting places. Employing PCR technique only three specimens of 150 P. papatasi (2%) were found naturally infected by parasites with a band of 350 bp which is equal to the L. major parasite. Forty six rodents were captured by Sherman traps and identified. Microscopic investigation on blood smear of the animals for amastigote parasites revealed 1 (3.22%) infected Meriones libycus (M. libycus). Infection of this animal to L. major was confirmed by PCR against rDNA loci of the parasite. This is the first molecular report of parasite infection of both vector (P. papatasi) and reservoir (M. libycus) to L. major in the region. The results indicated that P. papatasi was the primary vector of the disease and circulating the parasite between human and reservoirs and M. libycus was the most important host reservoir for maintenance of the parasite source in the area. Copyright © 2011 Hainan Medical College. Published by Elsevier B.V. All rights reserved.

Education, Training, and Employment Outcomes: Analysis of a National Survey of Employers. Final Technical Report.

ERIC Educational Resources Information Center

Hollenbeck, Kevin

A study examined the effect of education and training on the economy and on employment outcomes. Data collected during a 1982 nationwide telephone survey of 3,500 employers were used as the basis for statistical models of voluntary and involuntary job separations and job promotions. Four major conclusions resulted from the modeling process…

The Employer Potential of MOOCs: A Mixed-Methods Study of Human Resource Professionals' Thinking on MOOCs

ERIC Educational Resources Information Center

Radford, Alexandria Walton; Robles, Jessica; Cataylo, Stacey; Horn, Laura; Thornton, Jessica; Whitfield, Keith E.

2014-01-01

While press coverage of MOOCs (massive open online courses) has been considerable and major MOOC providers are beginning to realize that employers may be a market for their courses, research on employers' receptivity to using MOOCs is scarce. To help fill this gap, the Finding and Developing Talent study surveyed 103 employers and interviewed a…

Students' Expectations about Earnings and Employment and the Experience of Recent University Graduates: Evidence from Cyprus

ERIC Educational Resources Information Center

Menon, Maria Eliophotou; Pashourtidou, Nicoletta; Polycarpou, Alexandros; Pashardes, Panos

2012-01-01

The employability of university graduates constitutes a major policy concern in both developed and developing nations. In this context, the present study uses self-reported data to compare the earnings and employment expectations of university students, and the realised earnings and employment paths of recent graduates. The sample consisted of 476…

Drought Assessment over the Four Major River Basins of India using GRACE-based estimates of Water Availability

NASA Astrophysics Data System (ADS)

Sinha, D.; Syed, T. H.

2017-12-01

Drought is a natural disaster that has mutilating consequences over agriculture, ecosystems, economy and the society. Over the past few decades, drought related catastrophe, associated with global climate change, has escalated all across the world. Identification and analysis of drought utilizing individual hydrologic variables may be inadequate owing to the multitude of factors that are associated with the phenomenon. Therefore it is crucial to develop techniques that warrant comprehensive monitoring and assessment of droughts. In this study we propose a novel drought index (Water Availability Index (WAI)) that comprehends all the aspects of meteorologic, agricultural and hydrologic droughts. The proposed framework underscores the conceptualization and utilization of water availability, quantified as an integrated estimate of land water storage, using Gravity Recovery and Climate Experiment (GRACE) observations, and precipitation. The methodology is employed over four major river basins of India (i.e. Ganga, Krishna, Godavari and Mahanadi) for a period of 155 months (April 2002 to February 2015). Results exhibit the potential of the propounded index (WAI) to recognize drought events and impart insightful quantification of drought severity. WAI also demonstrates enhanced outcomes in comparison to other commonly used drought indices like PDSI, SPI, SPEI and SRI. In general there are at least three major drought periods with intensities ranging from moderate to severe in almost all river basins. The longest drought period, extending for 27 months, from September 2008 to November 2010, is observed in the Mahanadi basin. Results from this study confirm the potential of this technique as an effective tool for the characterization of drought at large spatial scales, which will only excel with better quantification and extended availability of terrestrial water storage observations from the GRACE-Follow On mission.

Imaging the North Anatolian Fault using the scattered teleseismic wavefield

NASA Astrophysics Data System (ADS)

Thompson, D. A.; Rost, S.; Houseman, G. A.; Cornwell, D. G.; Turkelli, N.; Teoman, U.; Kahraman, M.; Altuncu Poyraz, S.; Gülen, L.; Utkucu, M.; Frederiksen, A. W.; Rondenay, S.

2013-12-01

The North Anatolian Fault Zone (NAFZ) is a major continental strike-slip fault system, similar in size and scale to the San Andreas system, that extends ˜1200 km across Turkey. In 2012, a new multidisciplinary project (FaultLab) was instigated to better understand deformation throughout the entire crust in the NAFZ, in particular the expected transition from narrow zones of brittle deformation in the upper crust to possibly broader shear zones in the lower crust/upper mantle and how these features contribute to the earthquake loading cycle. This contribution will discuss the first results from the seismic component of the project, a 73 station network encompassing the northern and southern branches of the NAFZ in the Sakarya region. The Dense Array for North Anatolia (DANA) is arranged as a 6×11 grid with a nominal station spacing of 7 km, with a further 7 stations located outside of the main grid. With the excellent resolution afforded by the DANA network, we will present images of crustal structure using the technique of teleseismic scattering tomography. The method uses a full waveform inversion of the teleseismic scattered wavefield coupled with array processing techniques to infer the properties and location of small-scale heterogeneities (with scales on the order of the seismic wavelength) within the crust. We will also present preliminary results of teleseismic scattering migration, another powerful method that benefits from the dense data coverage of the deployed seismic network. Images obtained using these methods together with other conventional imaging techniques will provide evidence for how the deformation is distributed within the fault zone at depth, providing constraints that can be used in conjunction with structural analyses of exhumed fault segments and models of geodetic strain-rate across the fault system. By linking together results from the complementary techniques being employed in the FaultLab project, we aim to produce a comprehensive picture of fault structure and dynamics throughout the crust and shallow upper mantle of this major active fault zone.

Employers' Responsibility for Social Services: Public Perceptions.

ERIC Educational Resources Information Center

Roff, Lucinda Lee; Klemmack, David L.

1985-01-01

Surveyed 2,207 Alabama residents to determine public perceptions about employer responsibility for social services. Results indicated that the majority of respondents believe employers have some responsibility for drug and alcohol counseling, family problem counseling, and day care. Race, sex, family, and educational differences are discussed. (BL)

The Educational and Instructional Responsibilities of Employers

ERIC Educational Resources Information Center

Suchy, Stanislaw

1977-01-01

Discusses the responsibilities of employers in Poland toward the continuing education of their employers. Major topics included are responsibilities of firms based on socioeconomic needs, main features of worker education within firms, continuing education programs for workers, and factors determining the development of the firms' educational and…

Employability: Review and Research Prospects

ERIC Educational Resources Information Center

Guilbert, Laure; Bernaud, Jean-Luc; Gouvernet, Brice; Rossier, Jérôme

2016-01-01

Professional transition, employment, and reemployment are major concerns for nations facing adverse economic situations. The employability construct represents a scientific challenge in order to better understand the relationship between the job seekers' issues and the expectations of the world of work. This paper presents a review of the concept…

The a priori SDR Estimation Techniques with Reduced Speech Distortion for Acoustic Echo and Noise Suppression

NASA Astrophysics Data System (ADS)

Thoonsaengngam, Rattapol; Tangsangiumvisai, Nisachon

This paper proposes an enhanced method for estimating the a priori Signal-to-Disturbance Ratio (SDR) to be employed in the Acoustic Echo and Noise Suppression (AENS) system for full-duplex hands-free communications. The proposed a priori SDR estimation technique is modified based upon the Two-Step Noise Reduction (TSNR) algorithm to suppress the background noise while preserving speech spectral components. In addition, a practical approach to determine accurately the Echo Spectrum Variance (ESV) is presented based upon the linear relationship assumption between the power spectrum of far-end speech and acoustic echo signals. The ESV estimation technique is then employed to alleviate the acoustic echo problem. The performance of the AENS system that employs these two proposed estimation techniques is evaluated through the Echo Attenuation (EA), Noise Attenuation (NA), and two speech distortion measures. Simulation results based upon real speech signals guarantee that our improved AENS system is able to mitigate efficiently the problem of acoustic echo and background noise, while preserving the speech quality and speech intelligibility.

Pre-Employment Skills Training Module for Adult Male Inmates at Riker's Island Correctional Facility.

ERIC Educational Resources Information Center

Johnson, Janice K.

An instructional program called "Passport to a Job" provided prerelease training for inmates at Riker's Island Correctional Facility. The inmates were taught the important steps in preparing for employment; how to identify and cope with discriminatory employment; and how to demonstrate the interview techniques of opening the interview…

Time series forecasting using ERNN and QR based on Bayesian model averaging

NASA Astrophysics Data System (ADS)

Pwasong, Augustine; Sathasivam, Saratha

2017-08-01

The Bayesian model averaging technique is a multi-model combination technique. The technique was employed to amalgamate the Elman recurrent neural network (ERNN) technique with the quadratic regression (QR) technique. The amalgamation produced a hybrid technique known as the hybrid ERNN-QR technique. The potentials of forecasting with the hybrid technique are compared with the forecasting capabilities of individual techniques of ERNN and QR. The outcome revealed that the hybrid technique is superior to the individual techniques in the mean square error sense.

Diagnosing Developmental Dyscalculia on the Basis of Reliable Single Case FMRI Methods: Promises and Limitations

PubMed Central

Dinkel, Philipp Johannes; Willmes, Klaus; Krinzinger, Helga; Konrad, Kerstin; Koten Jr, Jan Willem

2013-01-01

FMRI-studies are mostly based on a group study approach, either analyzing one group or comparing multiple groups, or on approaches that correlate brain activation with clinically relevant criteria or behavioral measures. In this study we investigate the potential of fMRI-techniques focusing on individual differences in brain activation within a test-retest reliability context. We employ a single-case analysis approach, which contrasts dyscalculic children with a control group of typically developing children. In a second step, a support-vector machine analysis and cluster analysis techniques served to investigate similarities in multivariate brain activation patterns. Children were confronted with a non-symbolic number comparison and a non-symbolic exact calculation task during fMRI acquisition. Conventional second level group comparison analysis only showed small differences around the angular gyrus bilaterally and the left parieto-occipital sulcus. Analyses based on single-case statistical procedures revealed that developmental dyscalculia is characterized by individual differences predominantly in visual processing areas. Dyscalculic children seemed to compensate for relative under-activation in the primary visual cortex through an upregulation in higher visual areas. However, overlap in deviant activation was low for the dyscalculic children, indicating that developmental dyscalculia is a disorder characterized by heterogeneous brain activation differences. Using support vector machine analysis and cluster analysis, we tried to group dyscalculic and typically developing children according to brain activation. Fronto-parietal systems seem to qualify for a distinction between the two groups. However, this was only effective when reliable brain activations of both tasks were employed simultaneously. Results suggest that deficits in number representation in the visual-parietal cortex get compensated for through finger related aspects of number representation in fronto-parietal cortex. We conclude that dyscalculic children show large individual differences in brain activation patterns. Nonetheless, the majority of dyscalculic children can be differentiated from controls employing brain activation patterns when appropriate methods are used. PMID:24349547

Diagnosing developmental dyscalculia on the basis of reliable single case FMRI methods: promises and limitations.

PubMed

Dinkel, Philipp Johannes; Willmes, Klaus; Krinzinger, Helga; Konrad, Kerstin; Koten, Jan Willem

2013-01-01

FMRI-studies are mostly based on a group study approach, either analyzing one group or comparing multiple groups, or on approaches that correlate brain activation with clinically relevant criteria or behavioral measures. In this study we investigate the potential of fMRI-techniques focusing on individual differences in brain activation within a test-retest reliability context. We employ a single-case analysis approach, which contrasts dyscalculic children with a control group of typically developing children. In a second step, a support-vector machine analysis and cluster analysis techniques served to investigate similarities in multivariate brain activation patterns. Children were confronted with a non-symbolic number comparison and a non-symbolic exact calculation task during fMRI acquisition. Conventional second level group comparison analysis only showed small differences around the angular gyrus bilaterally and the left parieto-occipital sulcus. Analyses based on single-case statistical procedures revealed that developmental dyscalculia is characterized by individual differences predominantly in visual processing areas. Dyscalculic children seemed to compensate for relative under-activation in the primary visual cortex through an upregulation in higher visual areas. However, overlap in deviant activation was low for the dyscalculic children, indicating that developmental dyscalculia is a disorder characterized by heterogeneous brain activation differences. Using support vector machine analysis and cluster analysis, we tried to group dyscalculic and typically developing children according to brain activation. Fronto-parietal systems seem to qualify for a distinction between the two groups. However, this was only effective when reliable brain activations of both tasks were employed simultaneously. Results suggest that deficits in number representation in the visual-parietal cortex get compensated for through finger related aspects of number representation in fronto-parietal cortex. We conclude that dyscalculic children show large individual differences in brain activation patterns. Nonetheless, the majority of dyscalculic children can be differentiated from controls employing brain activation patterns when appropriate methods are used.

From Bachelor's Degree to Work: Major Field of Study and Employment Outcomes of 1992-93 Bachelor's Degree Recipients Who Did Not Enroll in Graduate Education by 1997.

ERIC Educational Resources Information Center

Horn, Laura J.; Zahn, Lisa

2001-01-01

Investigated the relationship between undergraduate major and early employment outcomes of college graduates who did not pursue graduate education within 4 years after earning their bachelor's degree. Data from the Baccalaureate and Beyond Study (National Center for Education Statistics) show that graduates who enter applied fields of engineering,…

Noncontact temperature measurements in the microgravity fluids and transport phenomena discipline

NASA Technical Reports Server (NTRS)

Salzman, Jack

1988-01-01

The program of activities within the Microgravity Fluids and Transport Phenomena Discipline has been structured to enable the systematic pursuit of an increased understanding of low gravity fluid behavior/phenomena in a way which ensures that the results are appropriate to the widest range of applications. This structure is discussed and an overview of some of the activities which are underway is given. Of significance is the fact that in the majority of the current and planned activities, the measurement and, or control of the fluid temperature is a key experiment requirement. In addition, many of the experiments require that the temperature measurement be nonintrusive. A description of these requirements together with the current techniques which are being employed or under study to make these measurements is also discussed.

A reconnaissance space sensing investigation of crustal structure for a strip from the eastern Sierra Nevada to the Colorado Plateau

NASA Technical Reports Server (NTRS)

Liggett, M. A. (Principal Investigator)

1974-01-01

The author has identified the following significant results. Research progress in an investigation using ERTS-1 MSS imagery to study regional tectonics and related natural resources is summarized. Field reconnaissance guided by analysis of ERTS-1 imagery has resulted in development of a tectonic model relating strike-slip faulting to crustal extension in the southern Basin Range Province. The tectonics of the northern Death Valley-Furnace Creek Fault Zone and spacially associated volcanism and mercury mineralization were also investigated. Field work in the southern Sierra Nevada has confirmed the existence of faults and diabase dike swarms aligned along several major lineaments first recognized in ERTS-1 imagery. Various image enhancement and analysis techniques employed in the study of ERTS-1 data are summarized.

Reduction of aircraft gas turbine engine pollutant emissions

NASA Technical Reports Server (NTRS)

Diehl, L. A.

1978-01-01

To accomplish simultaneous reduction of unburned hydrocarbons, carbon monoxide, and oxides of nitrogen, required major modifications to the combustor. The modification most commonly used was a staged combustion technique. While these designs are more complicated than production combustors, no insurmountable operational difficulties were encountered in either high pressure rig or engine tests which could not be resolved with additional normal development. The emission reduction results indicate that reductions in unburned hydrocarbons were sufficient to satisfy both near and far-termed EPA requirements. Although substantial reductions were observed, the success in achieving the CO and NOx standards was mixed and depended heavily on the engine/engine cycle on which it was employed. Technology for near term CO reduction was satisfactory or marginally satisfactory. Considerable doubt exists if this technology will satisfy all far-term requirements.

Continuous-time system identification of a smoking cessation intervention

NASA Astrophysics Data System (ADS)

Timms, Kevin P.; Rivera, Daniel E.; Collins, Linda M.; Piper, Megan E.

2014-07-01

Cigarette smoking is a major global public health issue and the leading cause of preventable death in the United States. Toward a goal of designing better smoking cessation treatments, system identification techniques are applied to intervention data to describe smoking cessation as a process of behaviour change. System identification problems that draw from two modelling paradigms in quantitative psychology (statistical mediation and self-regulation) are considered, consisting of a series of continuous-time estimation problems. A continuous-time dynamic modelling approach is employed to describe the response of craving and smoking rates during a quit attempt, as captured in data from a smoking cessation clinical trial. The use of continuous-time models provide benefits of parsimony, ease of interpretation, and the opportunity to work with uneven or missing data.

Chewing the fat: lipid metabolism and homeostasis during M. tuberculosis infection.

PubMed

Lovewell, Rustin R; Sassetti, Christopher M; VanderVen, Brian C

2016-02-01

The interplay between Mycobacterium tuberculosis lipid metabolism, the immune response and lipid homeostasis in the host creates a complex and dynamic pathogen-host interaction. Advances in imaging and metabolic analysis techniques indicate that M. tuberculosis preferentially associates with foamy cells and employs multiple physiological systems to utilize exogenously derived fatty-acids and cholesterol. Moreover, novel insights into specific host pathways that control lipid accumulation during infection, such as the PPARγ and LXR transcriptional regulators, have begun to reveal mechanisms by which host immunity alters the bacterial micro-environment. As bacterial lipid metabolism and host lipid regulatory pathways are both important, yet inherently complex, components of active tuberculosis, delineating the heterogeneity in lipid trafficking within disease states remains a major challenge for therapeutic design. Copyright © 2015. Published by Elsevier Ltd.

Glaucoma management: relative value and place in therapy of available drug treatments

PubMed Central

Sambhara, Deepak

2014-01-01

Lowering intraocular pressure (IOP) is the only proven therapeutic intervention for glaucomatous optic neuropathy. Despite advances in laser and microsurgical techniques, medical IOP reduction remains the first-line treatment option for the majority of patients with open-angle glaucoma. Prostaglandin analogs are the most efficacious topical agents and carry a remarkable safety profile. Topical beta-blockers, alpha-agonists, and carbonic anhydrase inhibitors are often employed as adjunctive agents for further IOP control. Newer preserved and nonpreserved formulations are available and appear to be less toxic to the ocular surface. Oral carbonic anhydrase inhibitors, miotic agents, and hyperosmotics are infrequently used due to a host of potentially serious adverse events. Medical therapies on the horizon include rho-kinase inhibitors, neuroprotective interventions, and gene therapies. PMID:24381726

Physical and property victimization behind bars: a multilevel examination.

PubMed

Lahm, Karen F

2009-06-01

The majority of the extant literature on inmate victimization considers only one level of analysis, thus ignoring the interaction effects between inmate- and prison-level variables. To extend this literature, multilevel modeling techniques were used to analyze self-report data from more than 1,000 inmates and 30 prisons in Kentucky, Tennessee, and Ohio. Results revealed that demographic variables were strong predictors of physical victimization (i.e., race and assaultive behavior). Also, security level had a contextual direct effect on physical victimization. Property victimization was best explained with an integrated model including inmate (i.e., race, assaultive behavior, prior education, prior employment, and time served), contextual (i.e., security level and proportion non-White), and micro-macro interaction variables (i.e., Race x Security Level). Policy implications and suggestions for future research are discussed.

Liquid chromatography-mass spectrometry identification of anthocyanins of isla oca (Oxalis tuberosa, Mol.) tubers.

PubMed

Alcalde-Eon, Cristina; Saavedra, Gloria; de Pascual-Teresa, Sonia; Rivas-Gonzalo, Julián C

2004-10-29

High-performance liquid chromatography (HPLC)-diode array detection (DAD)-mass spectrometry (MS) techniques have been successfully employed in the identification of the anthocyanins of the coloured tubers of isla oca (Oxalis tuberosa), the second most cultivated tuber in the Andean region. Tubers underwent a pre-treatment step in order to inhibit enzymatic reactions and to obtain a stable powder or "concentrate". This concentrate was dissolved, purified and then analysed. Eight different compounds were found. The major peaks were malvidin glucosides (malvidin 3-O-glucoside and 3,5-O-diglucoside). The rest of the peaks were 3,5-O-diglucosides of petunidin and peonidin, and 3-O-glucosides of delphinidin, petunidin and peonidin. Only malvidin 3-O-acetylglucoside-5-O-glucoside was found as an acylated anthocyanin.

Discrete Wavelet Transform for Fault Locations in Underground Distribution System

NASA Astrophysics Data System (ADS)

Apisit, C.; Ngaopitakkul, A.

2010-10-01

In this paper, a technique for detecting faults in underground distribution system is presented. Discrete Wavelet Transform (DWT) based on traveling wave is employed in order to detect the high frequency components and to identify fault locations in the underground distribution system. The first peak time obtained from the faulty bus is employed for calculating the distance of fault from sending end. The validity of the proposed technique is tested with various fault inception angles, fault locations and faulty phases. The result is found that the proposed technique provides satisfactory result and will be very useful in the development of power systems protection scheme.

Bidirectional and simultaneous FTTX/Ethernet services using RSOA based remodulation and polarization multiplexing technique

NASA Astrophysics Data System (ADS)

Das, Anindya S.; Patra, Ardhendu S.

2015-08-01

A bidirectional and simultaneous transmission of Ethernet, FTTX services through single optical carrier wavelength employing polarization multiplexing technique in the transmitter end and the user end. 10 Gbps and 2.5 Gbps datarates are transmitted over 50 km single mode fiber employing POLMUX technique at OLT and ONU to provide Ethernet and FTTX services concurrently to the user. Reflective semiconductor optical amplifier is used to reuse and remodulate the downlink signal to uplink transmission. The upstream and the downstream transmission performances are observed by the bit error rate values and the eye diagrams obtained by the BER analyzer.

Study of Belousov—Zhabotinsky oscillators in water—acetonitrile medium employing EMF and EPR techniques with o-vanillin, p-vanillin and adrenaline as substrates

NASA Astrophysics Data System (ADS)

Lalitha, P. V.; Ramaswamy, R.; Ramakrishnan, Geetha; Rao, P. Sambasiva

1994-12-01

The oscillatory behaviour of three substrates, ortho-vanillin, para-vanillin and adrenaline, in mixed media (water plus 20% acetonitrile) has been investigated using EPR and EMF techniques. All these substrates exhibit two types of oscillation involving Br 2/Br - and Mn(III)/Mn(II) redox couples. From the oscillatory characteristics (total time, number of oscillations and time per oscillation) obtained by employing these techniques, the reactivities of the vanillins have been correlated. The Field—Koros—Noyes mechanism, suggested for catalysed systems in pure aqueous medium, is established to be applicable even in mixed media.

Lagrangian Modeling of Evaporating Sprays at Diesel Engine Conditions: Effects of Multi-Hole Injector Nozzles With JP-8 Surrogates

DTIC Science & Technology

2014-05-01

solver to treat the spray process. An Adaptive Mesh Refinement (AMR) and fixed embedding technique is employed to capture the gas - liquid interface with...Adaptive Mesh Refinement (AMR) and fixed embedding technique is employed to capture the gas - liquid interface with high fidelity while keeping the cell...in single and multi-hole nozzle configurations. The models were added to the present CONVERGE liquid fuel database and validated extensively

The value of job analysis, job description and performance.

PubMed

Wolfe, M N; Coggins, S

1997-01-01

All companies, regardless of size, are faced with the same employment concerns. Efficient personnel management requires the use of three human resource techniques--job analysis, job description and performance appraisal. These techniques and tools are not for large practices only. Small groups can obtain the same benefits by employing these performance control measures. Job analysis allows for the development of a compensation system. Job descriptions summarize the most important duties. Performance appraisals help reward outstanding work.

Employment Issues in Higher Education: A Legal Compendium.

ERIC Educational Resources Information Center

Sagan, Jean S., Ed.; Rebel, Thomas P., Ed.

This volume contains 32 articles and sample documents treating legal issues in higher education employment focusing on major issues arising in a non-unionized setting. The first of six sections contains seven articles on the employment relationship in general that touch on current legal trends in employee selection procedures, employment…

Consistent modelling of wind turbine noise propagation from source to receiver.

PubMed

Barlas, Emre; Zhu, Wei Jun; Shen, Wen Zhong; Dag, Kaya O; Moriarty, Patrick

2017-11-01

The unsteady nature of wind turbine noise is a major reason for annoyance. The variation of far-field sound pressure levels is not only caused by the continuous change in wind turbine noise source levels but also by the unsteady flow field and the ground characteristics between the turbine and receiver. To take these phenomena into account, a consistent numerical technique that models the sound propagation from the source to receiver is developed. Large eddy simulation with an actuator line technique is employed for the flow modelling and the corresponding flow fields are used to simulate sound generation and propagation. The local blade relative velocity, angle of attack, and turbulence characteristics are input to the sound generation model. Time-dependent blade locations and the velocity between the noise source and receiver are considered within a quasi-3D propagation model. Long-range noise propagation of a 5 MW wind turbine is investigated. Sound pressure level time series evaluated at the source time are studied for varying wind speeds, surface roughness, and ground impedances within a 2000 m radius from the turbine.

Mixed infections in tuberculosis: The missing part in a puzzle.

PubMed

Tarashi, Samira; Fateh, Abolfazl; Mirsaeidi, Mehdi; Siadat, Seyed Davar; Vaziri, Farzam

2017-12-01

The mixed strains infection phenomenon is a major problem posing serious challenges in control of tuberculosis (TB). In patients with mixed infection, several different strains of Mycobacterium tuberculosis can be isolated simultaneously. Although different genotyping methods and various molecular approaches can be employed for detection of mixed infection in clinical samples, the MIRU-VNTR technique is more sensitive with higher discriminative power than many widely used techniques. Furthermore, the recent introduction of whole genome sequencing (WGS) promises to reveal more details about mixed infection with high resolution. WGS has been used for detection of mixed infection with high sensitivity and discriminatory, but the technology is currently limited to developed countries. Mixed infection may involve strains with different susceptibility patterns, which may alter the treatment outcome. In this report, we review the current concepts of mixed strains infection and also infection involving strains with a different susceptibility pattern in TB. We evaluate the importance of identifying mixed infection for diagnosis as well as treatment and highlight the accuracy and clinical utility of direct genotyping of clinical specimens. Copyright © 2017 Elsevier Ltd. All rights reserved.

State Tracking and Fault Diagnosis for Dynamic Systems Using Labeled Uncertainty Graph.

PubMed

Zhou, Gan; Feng, Wenquan; Zhao, Qi; Zhao, Hongbo

2015-11-05

Cyber-physical systems such as autonomous spacecraft, power plants and automotive systems become more vulnerable to unanticipated failures as their complexity increases. Accurate tracking of system dynamics and fault diagnosis are essential. This paper presents an efficient state estimation method for dynamic systems modeled as concurrent probabilistic automata. First, the Labeled Uncertainty Graph (LUG) method in the planning domain is introduced to describe the state tracking and fault diagnosis processes. Because the system model is probabilistic, the Monte Carlo technique is employed to sample the probability distribution of belief states. In addition, to address the sample impoverishment problem, an innovative look-ahead technique is proposed to recursively generate most likely belief states without exhaustively checking all possible successor modes. The overall algorithms incorporate two major steps: a roll-forward process that estimates system state and identifies faults, and a roll-backward process that analyzes possible system trajectories once the faults have been detected. We demonstrate the effectiveness of this approach by applying it to a real world domain: the power supply control unit of a spacecraft.

Experiments with a New, Unique Large-Scale Rig Investigating the Effects of Background System Rotation on Vortex Rings in Water

NASA Astrophysics Data System (ADS)

Brend, Mark A.; Verzicco, Roberto

2005-11-01

We introduce our unique, new large-scale experimental facility [1] designed for our long-term research program investigating the effects of background system rotation on the stability and the dynamics of vortex rings. The new rig constitutes a large water-filled tank positioned on a rotating turntable and its overall height and diameter are 5.7m and 1.4 m, respectively. First experimental and computational results of our program are summarized. We will show various videos of flow visualizations that illustrate some major, qualitative differences between rings propagating in rotating and non-rotating flows. Some of the investigated characteristics of the vortex rings include their translation velocity, the velocity field inside and surrounding the rings, and, in particular, their stability. We will briefly outline experiments employing the relatively new Ultrasonic-Velocity-Profiler technique (UVP). This technique appears to be particularly suited for some of our measurements and it was, as far as we are aware, not previously used in the context of vortex-ring studies. [1] http://www.eng.warwick.ac.uk/staff/pjt/turntabpics/voriskt.html

Consistent modelling of wind turbine noise propagation from source to receiver

DOE PAGES

Barlas, Emre; Zhu, Wei Jun; Shen, Wen Zhong; ...

2017-11-28

The unsteady nature of wind turbine noise is a major reason for annoyance. The variation of far-field sound pressure levels is not only caused by the continuous change in wind turbine noise source levels but also by the unsteady flow field and the ground characteristics between the turbine and receiver. To take these phenomena into account, a consistent numerical technique that models the sound propagation from the source to receiver is developed. Large eddy simulation with an actuator line technique is employed for the flow modelling and the corresponding flow fields are used to simulate sound generation and propagation. Themore » local blade relative velocity, angle of attack, and turbulence characteristics are input to the sound generation model. Time-dependent blade locations and the velocity between the noise source and receiver are considered within a quasi-3D propagation model. Long-range noise propagation of a 5 MW wind turbine is investigated. Sound pressure level time series evaluated at the source time are studied for varying wind speeds, surface roughness, and ground impedances within a 2000 m radius from the turbine.« less

Consistent modelling of wind turbine noise propagation from source to receiver

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barlas, Emre; Zhu, Wei Jun; Shen, Wen Zhong

The unsteady nature of wind turbine noise is a major reason for annoyance. The variation of far-field sound pressure levels is not only caused by the continuous change in wind turbine noise source levels but also by the unsteady flow field and the ground characteristics between the turbine and receiver. To take these phenomena into account, a consistent numerical technique that models the sound propagation from the source to receiver is developed. Large eddy simulation with an actuator line technique is employed for the flow modelling and the corresponding flow fields are used to simulate sound generation and propagation. Themore » local blade relative velocity, angle of attack, and turbulence characteristics are input to the sound generation model. Time-dependent blade locations and the velocity between the noise source and receiver are considered within a quasi-3D propagation model. Long-range noise propagation of a 5 MW wind turbine is investigated. Sound pressure level time series evaluated at the source time are studied for varying wind speeds, surface roughness, and ground impedances within a 2000 m radius from the turbine.« less

A numerical approach to controller design for the ACES facility

NASA Technical Reports Server (NTRS)

Frazier, W. Garth; Irwin, R. Dennis

1993-01-01

In recent years the employment of active control techniques for improving the performance of systems involving highly flexible structures has become a topic of considerable research interest. Most of these systems are quite complicated, using multiple actuators and sensors, and possessing high order models. The majority of analytical controller synthesis procedures capable of handling multivariable systems in a systematic way require considerable insight into the underlying mathematical theory to achieve a successful design. This insight is needed in selecting the proper weighting matrices or weighting functions to cast what is naturally a multiple constraint satisfaction problem into an unconstrained optimization problem. Although designers possessing considerable experience with these techniques have a feel for the proper choice of weights, others may spend a significant amount of time attempting to find an acceptable solution. Another disadvantage of such procedures is that the resulting controller has an order greater than or equal to that of the model used for the design. Of course, the order of these controllers can often be reduced, but again this requires a good understanding of the theory involved.

Three-dimensional Boltzmann-Hydro Code for Core-collapse in Massive Stars. II. The Implementation of Moving-mesh for Neutron Star Kicks

NASA Astrophysics Data System (ADS)

Nagakura, Hiroki; Iwakami, Wakana; Furusawa, Shun; Sumiyoshi, Kohsuke; Yamada, Shoichi; Matsufuru, Hideo; Imakura, Akira

2017-04-01

We present a newly developed moving-mesh technique for the multi-dimensional Boltzmann-Hydro code for the simulation of core-collapse supernovae (CCSNe). What makes this technique different from others is the fact that it treats not only hydrodynamics but also neutrino transfer in the language of the 3 + 1 formalism of general relativity (GR), making use of the shift vector to specify the time evolution of the coordinate system. This means that the transport part of our code is essentially general relativistic, although in this paper it is applied only to the moving curvilinear coordinates in the flat Minknowski spacetime, since the gravity part is still Newtonian. The numerical aspect of the implementation is also described in detail. Employing the axisymmetric two-dimensional version of the code, we conduct two test computations: oscillations and runaways of proto-neutron star (PNS). We show that our new method works fine, tracking the motions of PNS correctly. We believe that this is a major advancement toward the realistic simulation of CCSNe.

True Ortho Generation of Urban Area Using High Resolution Aerial Photos

NASA Astrophysics Data System (ADS)

Hu, Yong; Stanley, David; Xin, Yubin

2016-06-01

The pros and cons of existing methods for true ortho generation are analyzed based on a critical literature review for its two major processing stages: visibility analysis and occlusion compensation. They process frame and pushbroom images using different algorithms for visibility analysis due to the need of perspective centers used by the z-buffer (or alike) techniques. For occlusion compensation, the pixel-based approach likely results in excessive seamlines in the ortho-rectified images due to the use of a quality measure on the pixel-by-pixel rating basis. In this paper, we proposed innovative solutions to tackle the aforementioned problems. For visibility analysis, an elevation buffer technique is introduced to employ the plain elevations instead of the distances from perspective centers by z-buffer, and has the advantage of sensor independency. A segment oriented strategy is developed to evaluate a plain cost measure per segment for occlusion compensation instead of the tedious quality rating per pixel. The cost measure directly evaluates the imaging geometry characteristics in ground space, and is also sensor independent. Experimental results are demonstrated using aerial photos acquired by UltraCam camera.

A global optimization perspective on molecular clusters.

PubMed

Marques, J M C; Pereira, F B; Llanio-Trujillo, J L; Abreu, P E; Albertí, M; Aguilar, A; Pirani, F; Bartolomei, M

2017-04-28

Although there is a long history behind the idea of chemical structure, this is a key concept that continues to challenge chemists. Chemical structure is fundamental to understanding most of the properties of matter and its knowledge for complex systems requires the use of state-of-the-art techniques, either experimental or theoretical. From the theoretical view point, one needs to establish the interaction potential among the atoms or molecules of the system, which contains all the information regarding the energy landscape, and employ optimization algorithms to discover the relevant stationary points. In particular, global optimization methods are of major importance to search for the low-energy structures of molecular aggregates. We review the application of global optimization techniques to several molecular clusters; some new results are also reported. Emphasis is given to evolutionary algorithms and their application in the study of the microsolvation of alkali-metal and Ca 2+ ions with various types of solvents.This article is part of the themed issue 'Theoretical and computational studies of non-equilibrium and non-statistical dynamics in the gas phase, in the condensed phase and at interfaces'. © 2017 The Author(s).

Ground test challenges in the development of the Space Shuttle orbiter auxiliary power unit

NASA Technical Reports Server (NTRS)

Chaffee, N. H.; Lance, R. J.; Weary, D. P.

1984-01-01

A conventional aircraft hydraulic system design approach was selected to provide fluid power for the Space Shuttle Orbiter. Developing the power unit, known as the Auxiliary Power Unit (APU), to drive the hydraulic pumps presented a major technological challenge. A small, high speed turbine drive unit powered by catalytically decomposed hydrazine and operating in the pulse mode was selected to meet the requirement. Because of limitations of vendor test facilities, significant portions of the development, flight qualification, and postflight anomaly testing of the Orbiter APU were accomplished at the Johnson Space Center (JSC) test facilities. This paper discusses the unique requirements of attitude, gravity forces, pressure profiles, and thermal environments which had to be satisfied by the APU, and presents the unique test facility and simulation techniques employed to meet the ground test requirements. In particular, the development of the zero-g lubrication system, the development of necessary APU thermal control techniques, the accomplishment of integrated systems tests, and the postflight investigation of the APU lube oil cooler behavior are discussed.

MRI of human hair.

PubMed

Mattle, Eveline; Weiger, Markus; Schmidig, Daniel; Boesiger, Peter; Fey, Michael

2009-06-01

Hair care for humans is a major world industry with specialised tools, chemicals and techniques. Studying the effect of hair care products has become a considerable field of research, and besides mechanical and optical testing numerous advanced analytical techniques have been employed in this area. In the present work, another means of studying the properties of hair is added by demonstrating the feasibility of magnetic resonance imaging (MRI) of the human hair. Established dedicated nuclear magnetic resonance microscopy hardware (solenoidal radiofrequency microcoils and planar field gradients) and methods (constant time imaging) were adapted to the specific needs of hair MRI. Images were produced at a spatial resolution high enough to resolve the inner structure of the hair, showing contrast between cortex and medulla. Quantitative evaluation of a scan series with different echo times provided a T*(2) value of 2.6 ms for the cortex and a water content of about 90% for hairs saturated with water. The demonstration of the feasibility of hair MRI potentially adds a new tool to the large variety of analytical methods used nowadays in the development of hair care products.

Human primary mixed brain cultures: preparation, differentiation, characterization and application to neuroscience research.

PubMed

Ray, Balmiki; Chopra, Nipun; Long, Justin M; Lahiri, Debomoy K

2014-09-16

Culturing primary cortical neurons is an essential neuroscience technique. However, most cultures are derived from rodent brains and standard protocols for human brain cultures are sparse. Herein, we describe preparation, maintenance and major characteristics of a primary human mixed brain culture, including neurons, obtained from legally aborted fetal brain tissue. This approach employs standard materials and techniques used in the preparation of rodent neuron cultures, with critical modifications. This culture has distinct differences from rodent cultures. Specifically, a significant numbers of cells in the human culture are derived from progenitor cells, and the yield and survival of the cells grossly depend on the presence of bFGF. In the presence of bFGF, this culture can be maintained for an extended period. Abundant productions of amyloid-β, tau and proteins make this a powerful model for Alzheimer's research. The culture also produces glia and different sub-types of neurons. We provide a well-characterized methodology for human mixed brain cultures useful to test therapeutic agents under various conditions, and to carry forward mechanistic and translational studies for several brain disorders.

A global optimization perspective on molecular clusters

PubMed Central

Pereira, F. B.; Llanio-Trujillo, J. L.; Abreu, P. E.; Albertí, M.; Aguilar, A.; Pirani, F.; Bartolomei, M.

2017-01-01

Although there is a long history behind the idea of chemical structure, this is a key concept that continues to challenge chemists. Chemical structure is fundamental to understanding most of the properties of matter and its knowledge for complex systems requires the use of state-of-the-art techniques, either experimental or theoretical. From the theoretical view point, one needs to establish the interaction potential among the atoms or molecules of the system, which contains all the information regarding the energy landscape, and employ optimization algorithms to discover the relevant stationary points. In particular, global optimization methods are of major importance to search for the low-energy structures of molecular aggregates. We review the application of global optimization techniques to several molecular clusters; some new results are also reported. Emphasis is given to evolutionary algorithms and their application in the study of the microsolvation of alkali-metal and Ca2+ ions with various types of solvents. This article is part of the themed issue ‘Theoretical and computational studies of non-equilibrium and non-statistical dynamics in the gas phase, in the condensed phase and at interfaces’. PMID:28320902

Assessment and application of clustering techniques to atmospheric particle number size distribution for the purpose of source apportionment

NASA Astrophysics Data System (ADS)

Salimi, F.; Ristovski, Z.; Mazaheri, M.; Laiman, R.; Crilley, L. R.; He, C.; Clifford, S.; Morawska, L.

2014-06-01

Long-term measurements of particle number size distribution (PNSD) produce a very large number of observations and their analysis requires an efficient approach in order to produce results in the least possible time and with maximum accuracy. Clustering techniques are a family of sophisticated methods which have been recently employed to analyse PNSD data, however, very little information is available comparing the performance of different clustering techniques on PNSD data. This study aims to apply several clustering techniques (i.e. K-means, PAM, CLARA and SOM) to PNSD data, in order to identify and apply the optimum technique to PNSD data measured at 25 sites across Brisbane, Australia. A new method, based on the Generalised Additive Model (GAM) with a basis of penalised B-splines, was proposed to parameterise the PNSD data and the temporal weight of each cluster was also estimated using the GAM. In addition, each cluster was associated with its possible source based on the results of this parameterisation, together with the characteristics of each cluster. The performances of four clustering techniques were compared using the Dunn index and silhouette width validation values and the K-means technique was found to have the highest performance, with five clusters being the optimum. Therefore, five clusters were found within the data using the K-means technique. The diurnal occurrence of each cluster was used together with other air quality parameters, temporal trends and the physical properties of each cluster, in order to attribute each cluster to its source and origin. The five clusters were attributed to three major sources and origins, including regional background particles, photochemically induced nucleated particles and vehicle generated particles. Overall, clustering was found to be an effective technique for attributing each particle size spectra to its source and the GAM was suitable to parameterise the PNSD data. These two techniques can help researchers immensely in analysing PNSD data for characterisation and source apportionment purposes.

Assessment and application of clustering techniques to atmospheric particle number size distribution for the purpose of source apportionment

NASA Astrophysics Data System (ADS)

Salimi, F.; Ristovski, Z.; Mazaheri, M.; Laiman, R.; Crilley, L. R.; He, C.; Clifford, S.; Morawska, L.

2014-11-01

Long-term measurements of particle number size distribution (PNSD) produce a very large number of observations and their analysis requires an efficient approach in order to produce results in the least possible time and with maximum accuracy. Clustering techniques are a family of sophisticated methods that have been recently employed to analyse PNSD data; however, very little information is available comparing the performance of different clustering techniques on PNSD data. This study aims to apply several clustering techniques (i.e. K means, PAM, CLARA and SOM) to PNSD data, in order to identify and apply the optimum technique to PNSD data measured at 25 sites across Brisbane, Australia. A new method, based on the Generalised Additive Model (GAM) with a basis of penalised B-splines, was proposed to parameterise the PNSD data and the temporal weight of each cluster was also estimated using the GAM. In addition, each cluster was associated with its possible source based on the results of this parameterisation, together with the characteristics of each cluster. The performances of four clustering techniques were compared using the Dunn index and Silhouette width validation values and the K means technique was found to have the highest performance, with five clusters being the optimum. Therefore, five clusters were found within the data using the K means technique. The diurnal occurrence of each cluster was used together with other air quality parameters, temporal trends and the physical properties of each cluster, in order to attribute each cluster to its source and origin. The five clusters were attributed to three major sources and origins, including regional background particles, photochemically induced nucleated particles and vehicle generated particles. Overall, clustering was found to be an effective technique for attributing each particle size spectrum to its source and the GAM was suitable to parameterise the PNSD data. These two techniques can help researchers immensely in analysing PNSD data for characterisation and source apportionment purposes.

Inserting ex vivo fluorescence confocal microscopy perioperatively in Mohs micrographic surgery expedites bedside assessment of excision margins in recurrent basal cell carcinoma.

PubMed

Longo, Caterina; Ragazzi, Moira; Castagnetti, Fabio; Gardini, Stefano; Palmieri, Tamara; Lallas, Aimilios; Moscarella, Elvira; Piana, Simonetta; Pellacani, Giovanni; Zalaudek, Iris; Argenziano, Giuseppe

2013-01-01

Mohs micrographic surgery can be employed in recurrent basal cell carcinoma, although it is a time-consuming technique. Recently, ex vivo fluorescence confocal microscopy (FCM) has been employed to obtain a fast assessment of tumor margins at the bedside. In our case we successfully employed ex vivo FCM to assess the tumor margins and we treated the persistent tumor with intensity-modulated radiation therapy. Our case demonstrates that a multidisciplinary approach is very efficient in managing complex and recurrent tumors and highlights the benefits of FCM as a new technique that can be used in the surgical theater to speed up the entire procedure.

Surface topography characterization using 3D stereoscopic reconstruction of SEM images

NASA Astrophysics Data System (ADS)

Vedantha Krishna, Amogh; Flys, Olena; Reddy, Vijeth V.; Rosén, B. G.

2018-06-01

A major drawback of the optical microscope is its limitation to resolve finer details. Many microscopes have been developed to overcome the limitations set by the diffraction of visible light. The scanning electron microscope (SEM) is one such alternative: it uses electrons for imaging, which have much smaller wavelength than photons. As a result high magnification with superior image resolution can be achieved. However, SEM generates 2D images which provide limited data for surface measurements and analysis. Often many research areas require the knowledge of 3D structures as they contribute to a comprehensive understanding of microstructure by allowing effective measurements and qualitative visualization of the samples under study. For this reason, stereo photogrammetry technique is employed to convert SEM images into 3D measurable data. This paper aims to utilize a stereoscopic reconstruction technique as a reliable method for characterization of surface topography. Reconstructed results from SEM images are compared with coherence scanning interferometer (CSI) results obtained by measuring a roughness reference standard sample. This paper presents a method to select the most robust/consistent surface texture parameters that are insensitive to the uncertainties involved in the reconstruction technique itself. Results from the two-stereoscopic reconstruction algorithms are also documented in this paper.

3D GRASE PROPELLER: improved image acquisition technique for arterial spin labeling perfusion imaging.

PubMed

Tan, Huan; Hoge, W Scott; Hamilton, Craig A; Günther, Matthias; Kraft, Robert A

2011-07-01

Arterial spin labeling is a noninvasive technique that can quantitatively measure cerebral blood flow. While traditionally arterial spin labeling employs 2D echo planar imaging or spiral acquisition trajectories, single-shot 3D gradient echo and spin echo (GRASE) is gaining popularity in arterial spin labeling due to inherent signal-to-noise ratio advantage and spatial coverage. However, a major limitation of 3D GRASE is through-plane blurring caused by T(2) decay. A novel technique combining 3D GRASE and a periodically rotated overlapping parallel lines with enhanced reconstruction trajectory (PROPELLER) is presented to minimize through-plane blurring without sacrificing perfusion sensitivity or increasing total scan time. Full brain perfusion images were acquired at a 3 × 3 × 5 mm(3) nominal voxel size with pulsed arterial spin labeling preparation sequence. Data from five healthy subjects was acquired on a GE 1.5T scanner in less than 4 minutes per subject. While showing good agreement in cerebral blood flow quantification with 3D gradient echo and spin echo, 3D GRASE PROPELLER demonstrated reduced through-plane blurring, improved anatomical details, high repeatability and robustness against motion, making it suitable for routine clinical use. Copyright © 2011 Wiley-Liss, Inc.

LC–MS/MS Quantitation of Esophagus Disease Blood Serum Glycoproteins by Enrichment with Hydrazide Chemistry and Lectin Affinity Chromatography

PubMed Central

2015-01-01

Changes in glycosylation have been shown to have a profound correlation with development/malignancy in many cancer types. Currently, two major enrichment techniques have been widely applied in glycoproteomics, namely, lectin affinity chromatography (LAC)-based and hydrazide chemistry (HC)-based enrichments. Here we report the LC–MS/MS quantitative analyses of human blood serum glycoproteins and glycopeptides associated with esophageal diseases by LAC- and HC-based enrichment. The separate and complementary qualitative and quantitative data analyses of protein glycosylation were performed using both enrichment techniques. Chemometric and statistical evaluations, PCA plots, or ANOVA test, respectively, were employed to determine and confirm candidate cancer-associated glycoprotein/glycopeptide biomarkers. Out of 139, 59 common glycoproteins (42% overlap) were observed in both enrichment techniques. This overlap is very similar to previously published studies. The quantitation and evaluation of significantly changed glycoproteins/glycopeptides are complementary between LAC and HC enrichments. LC–ESI–MS/MS analyses indicated that 7 glycoproteins enriched by LAC and 11 glycoproteins enriched by HC showed significantly different abundances between disease-free and disease cohorts. Multiple reaction monitoring quantitation resulted in 13 glycopeptides by LAC enrichment and 10 glycosylation sites by HC enrichment to be statistically different among disease cohorts. PMID:25134008

Analyzing simulation-based PRA data through traditional and topological clustering: A BWR station blackout case study

DOE PAGES

Maljovec, D.; Liu, S.; Wang, B.; ...

2015-07-14

Here, dynamic probabilistic risk assessment (DPRA) methodologies couple system simulator codes (e.g., RELAP and MELCOR) with simulation controller codes (e.g., RAVEN and ADAPT). Whereas system simulator codes model system dynamics deterministically, simulation controller codes introduce both deterministic (e.g., system control logic and operating procedures) and stochastic (e.g., component failures and parameter uncertainties) elements into the simulation. Typically, a DPRA is performed by sampling values of a set of parameters and simulating the system behavior for that specific set of parameter values. For complex systems, a major challenge in using DPRA methodologies is to analyze the large number of scenarios generated,more » where clustering techniques are typically employed to better organize and interpret the data. In this paper, we focus on the analysis of two nuclear simulation datasets that are part of the risk-informed safety margin characterization (RISMC) boiling water reactor (BWR) station blackout (SBO) case study. We provide the domain experts a software tool that encodes traditional and topological clustering techniques within an interactive analysis and visualization environment, for understanding the structures of such high-dimensional nuclear simulation datasets. We demonstrate through our case study that both types of clustering techniques complement each other for enhanced structural understanding of the data.« less

Personal Photo Enhancement Using Internet Photo Collections.

PubMed

Zhang, Chenxi; Gao, Jizhou; Wang, Oliver; Georgel, Pierre; Yang, Ruigang; Davis, James; Frahm, Jan-Michael; Pollefeys, Marc

2013-04-26

Given the growth of Internet photo collections we now have a visual index of all major cities and tourist sites in the world. However, it is still a difficult task to capture that perfect shot with your own camera when visiting these places, especially when your camera itself has limitations, such as a limited field of view. In this paper, we propose a framework to overcome the imperfections of personal photos of tourist sites using the rich information provided by large scale Internet photo collections. Our method deploys state-of-the-art techniques for constructing initial 3D models from photo collections. The same techniques are then used to register personal photos to these models, allowing us to augment personal 2D images with 3D information. This strong available scene prior allows us to address a number of traditionally challenging image enhancement techniques, and achieve high quality results using simple and robust algorithms. Specifically, we demonstrate automatic foreground segmentation, mono-to-stereo conversion, the field of view expansion, photometric enhancement, and additionally automatic annotation with geo-location and tags. Our method clearly demonstrates some possible benefits of employing the rich information contained in on-line photo databases to efficiently enhance and augment one’s own personal photos.

Monitoring of pipeline ruptures by means of a Robust Satellite Technique (RST)

NASA Astrophysics Data System (ADS)

Filizzola, C.; Baldassarre, G.; Corrado, R.; Mazzeo, G.; Marchese, F.; Paciello, R.; Pergola, N.; Tramutoli, V.

2009-04-01

Pipeline ruptures have deep economic and ecologic consequences so that pipeline networks represent critical infrastructures to be carefully monitored particularly in areas which are frequently affected by natural disasters like earthquakes, hurricanes, landslide, etc. In order to minimize damages, the detection of harmful events along pipelines should be as rapid as possible and, at the same time, what is detected should be an actual incident and not a false alarm. In this work, a Robust Satellite Technique (RST), already applied to the prevision and NRT (Near Real Time) monitoring of major natural and environmental hazards (such as seismically active areas, volcanic activity, hydrological risk, forest fires and oil spills) has been employed to automatically identify, from satellite, anomalous Thermal Infrared (TIR) transients related to explosions of oil/gas pipelines. In this context, the combination of the RST approach with high temporal resolution, offered by geostationary satellites, seems to assure both a reliable and timely detection of such events. The potentials of the technique (applied to MSG-SEVIRI data) were tested over Iraq, a region which is sadly known for the numerous (mainly manmade) accidents to pipelines, in order to have a simulation of the effects (such as fires or explosions near or directly involving a pipeline facility) due to natural disasters.

Molecular Approaches for High Throughput Detection and Quantification of Genetically Modified Crops: A Review

PubMed Central

Salisu, Ibrahim B.; Shahid, Ahmad A.; Yaqoob, Amina; Ali, Qurban; Bajwa, Kamran S.; Rao, Abdul Q.; Husnain, Tayyab

2017-01-01

As long as the genetically modified crops are gaining attention globally, their proper approval and commercialization need accurate and reliable diagnostic methods for the transgenic content. These diagnostic techniques are mainly divided into two major groups, i.e., identification of transgenic (1) DNA and (2) proteins from GMOs and their products. Conventional methods such as PCR (polymerase chain reaction) and enzyme-linked immunosorbent assay (ELISA) were routinely employed for DNA and protein based quantification respectively. Although, these Techniques (PCR and ELISA) are considered as significantly convenient and productive, but there is need for more advance technologies that allow for high throughput detection and the quantification of GM event as the production of more complex GMO is increasing day by day. Therefore, recent approaches like microarray, capillary gel electrophoresis, digital PCR and next generation sequencing are more promising due to their accuracy and precise detection of transgenic contents. The present article is a brief comparative study of all such detection techniques on the basis of their advent, feasibility, accuracy, and cost effectiveness. However, these emerging technologies have a lot to do with detection of a specific event, contamination of different events and determination of fusion as well as stacked gene protein are the critical issues to be addressed in future. PMID:29085378

Corporate smoking cessation on Long Island.

PubMed

Mulligan, Peter

2010-03-01

Tobacco addiction is a treatable health care problem. Employers are experiencing major annual increases in the cost of providing health insurance benefits. The expenditures due to smoking-related diseases are a major contributor to the escalating cost of employer-sponsored health and life benefit plans. An initiative that employers have adopted to help control increases in health care costs as well as improve the lifestyle of employees is the establishment of corporate wellness programs. Programs that promote healthy lifestyles and wellness are connected to the principle that a happy and healthy worker will be more effective and productive. Another dividend of corporate wellness programs is higher employee retention and better employee morale. An earlier study investigated the impact of wellness programs for Long Island employers. One of the major findings of that research was the confirmation of the prevalence of smoking cessation initiatives as components of the successful wellness programs. This article, through analysis of a follow-up survey, confirms that corporate smoking cessation programs have a significant return on investment. Further, the analysis identifies the components of the cessation programs and measures the relative impact of each element.

ATTITUDE OF CLEFT CARE SPECIALISTS IN AFRICA TOWARDS PRESURGICAL ORTHOPAEDICS.

PubMed

Adeyemi, A T; Bankole, O O

2012-12-01

To determine the attitude of cleft care specialists working in Africa towards pre-surgical orthopaedics. A cross sectional study. Pan-African conference on cleft lip and palate in Nigeria. Sixty cleft care specialists working in Africa. The general attitude towards pre-surgicalorthopaedics was positive. Majority of the specialists employ pre-surgical orthopaedics before surgical repair. Fifty four (91%) of the specialists use plaster strapping for cases of bilateral cleft, five (8.3%) use nasoalveolar molding and one (2%) use feeding plate. Half of the specialists (50%) felt that pre-surgical orthopaedics is to be managed by orthodontists alone. There were significant difference in attitude towards pre-surgical orthopaedics between providers (p < 0.05). Orthodontists had a strong positive attitude towards pre-surgical orthopaedics than other specialists. Younger specialists had a more positive attitude towards pre-surgical orthopaedics than older specialists. Cleft care specialists in Africa have a positive attitude towards pre-surgical orthopaedics. Majority of them use plaster strapping technique. Younger specialists have a more favorable attitude towards pre-surgical orthopaedics than older specialists.

Vegetation mapping of Nowitna National Wildlife Reguge, Alaska using Landsat MSS digital data

USGS Publications Warehouse

Talbot, S. S.; Markon, Carl J.

1986-01-01

A Landsat-derived vegetation map was prepared for Nowitna National Wildlife Refuge. The refuge lies within the middle boreal subzone of north central Alaska. Seven major vegetation classes and sixteen subclasses were recognized: forest (closed needleleaf, open needleleaf, needleleaf woodland, mixed, and broadleaf); broadleaf scrub (lowland, alluvial, subalpine); dwarf scrub (prostrate dwarf shrub tundra, dwarf shrub-graminoid tussock peatland); herbaceous (graminoid bog, marsh and meadow); scarcely vegetated areas (scarcely vegetated scree and floodplain); water (clear, turbid); and other areas (mountain shadow). The methodology employed a cluster-block technique. Sample areas were described based on a combination of helicopter-ground survey, aerial photointerpretation, and digital Landsat data. Major steps in the Landsat analysis involved preprocessing (geometric correction), derivation of statistical parameters for spectral classes, spectral class labeling of sample areas, preliminary classification of the entire study area using a maximum-likelihood algorithm, and final classification utilizing ancillary information such as digital elevation data. The final product is a 1:250,000-scale vegetation map representative of distinctive regional patterns and suitable for use in comprehensive conservation planning.

Full-f version of GENE for turbulence in open-field-line systems

NASA Astrophysics Data System (ADS)

Pan, Q.; Told, D.; Shi, E. L.; Hammett, G. W.; Jenko, F.

2018-06-01

Unique properties of plasmas in the tokamak edge, such as large amplitude fluctuations and plasma-wall interactions in the open-field-line regions, require major modifications of existing gyrokinetic codes originally designed for simulating core turbulence. To this end, the global version of the 3D2V gyrokinetic code GENE, so far employing a δf-splitting technique, is extended to simulate electrostatic turbulence in straight open-field-line systems. The major extensions are the inclusion of the velocity-space nonlinearity, the development of a conducting-sheath boundary, and the implementation of the Lenard-Bernstein collision operator. With these developments, the code can be run as a full-f code and can handle particle loss to and reflection from the wall. The extended code is applied to modeling turbulence in the Large Plasma Device (LAPD), with a reduced mass ratio and a much lower collisionality. Similar to turbulence in a tokamak scrape-off layer, LAPD turbulence involves collisions, parallel streaming, cross-field turbulent transport with steep profiles, and particle loss at the parallel boundary.

Speaker gender identification based on majority vote classifiers

NASA Astrophysics Data System (ADS)

Mezghani, Eya; Charfeddine, Maha; Nicolas, Henri; Ben Amar, Chokri

2017-03-01

Speaker gender identification is considered among the most important tools in several multimedia applications namely in automatic speech recognition, interactive voice response systems and audio browsing systems. Gender identification systems performance is closely linked to the selected feature set and the employed classification model. Typical techniques are based on selecting the best performing classification method or searching optimum tuning of one classifier parameters through experimentation. In this paper, we consider a relevant and rich set of features involving pitch, MFCCs as well as other temporal and frequency-domain descriptors. Five classification models including decision tree, discriminant analysis, nave Bayes, support vector machine and k-nearest neighbor was experimented. The three best perming classifiers among the five ones will contribute by majority voting between their scores. Experimentations were performed on three different datasets spoken in three languages: English, German and Arabic in order to validate language independency of the proposed scheme. Results confirm that the presented system has reached a satisfying accuracy rate and promising classification performance thanks to the discriminating abilities and diversity of the used features combined with mid-level statistics.

Night-time lights as a proxy of human pressure on freshwater resources

NASA Astrophysics Data System (ADS)

Ceola, Serena; Montanari, Alberto; Laio, Francesco

2017-04-01

The presence and availability of freshwater resources at the global scale control the dynamics and the biodiversity of river ecosystems, as well as the human development and the security of people and economies. The increasing human pressure on freshwater is known to potentially drive significant alterations on both ecohydrological and social dynamics. To date, a spatially-detailed snapshot (i.e. single in time) analysis of human water security and river biodiversity threats revealed that the majority of the world's population and river ecosystems are exposed to high levels of endangerment. However, the temporal evolution of these effects at the global scale is still unexplored. To this aim, moving from the recent progress on remote sensing techniques, we employed yearly averaged night-time light images available from 1992 to 2013 as a proxy of anthropogenic presence and activity and we investigated how threats to human water security and river biodiversity evolved in time in 405 major river basins. Our results show a consistent correlation between nightlights and ecohydrological and threats, providing innovative support for freshwater resources management.

Seasonal changes in the techniques employed by wild chimpanzees in the Mahale Mountains, Tanzania, to feed on termites (Pseudacanthotermes spiniger).

PubMed

Uehara, S

1982-01-01

During a short period, wild chimpanzees of group K in the Mahale Mountains employ a set of several techniques, including tool use, to feed on one species of termite (Pseudacanthotermes spiniger). They appear to use each technique appropriately according to phenological changes in the prey insect's activities. The chimpanzees also ingest small pieces of soil from the tower of P. spiniger's mound throughout the year. Geophagy presumably makes them visually and tactually aware of the phenological changes of the termite's reproductive cycle. Analyses of fecal samples from the chimpanzees indicate interannual fluctuations in the amount of termites ingested. On the other hand, the chimpanzees of group B, ranging to the north of group K, utilize a fishing technique to obtain another type of termite (Macrotermes?herus) on a large scale during the first half of the wet season. Fecal analysis data show that chimpanzees of group B consume far more termites than those of group K. The probability that the same or similar tool-using techniques as fishing may be employed in feeding on different types of insects by chimpanzees of different unit groups according to subtle local differences in the insect fauna of their home ranges is discussed.

Pre-placement screenings: An exploratory study of their use in a sample of New South Wales workplaces.

PubMed

McHugh, Cate; Gibson, Libby

2011-01-01

To conduct an exploratory pilot study of pre-placement screening practice in Australia by examining the nature and use of pre-placement screenings in a sample of New South Wales (NSW) workplaces. 29 of 279 employers (10.3%) invited using three sources: a public list of self-insured NSW companies, a regional chamber of commerce group and researcher's contacts. The majority of respondents (31%) belonged to government administration and education. Half of the workplaces employed more than 200 people. Employers completed an online survey from a link sent by email. Sixteen (55%) of the companies had a formal process for conducting pre-placement screenings, that were conducted by a range of professionals using a variety of methods, with costs ranging from $80 to $350 (Aus). The majority of respondents (81%) reported that the pre-placement screenings included an assessment of the person's ability to perform the specific physical demands of the job, i.e. against the specified physical demands of the position. The majority of employers who completed screenings found them useful. The findings, while from a small sample size, provide evidence that pre-placement screenings are being conducted in Australian workplaces by various professionals, using varying methods and are valued by employers.

C-band station coordinate determination for the GEOS-C altimeter calibration area

NASA Technical Reports Server (NTRS)

Krabill, W. B.; Klosko, S. M.

1974-01-01

Dynamical orbital techniques were employed to estimate the center-of-mass station coordinates of six C-band radars located in the designated primary GEOS-C radar altimeter calibration area. This work was performed in support of the planned GEOS-C mission (December, 1974 launch). The sites included Bermuda, Grand Turk, Antigua, Wallops Island (Virginia), and Merritt Island (Florida). Two sites were estimated independently at Wallops Island yielding better than 40 cm relative height recovery, with better than 10 cm and 1 m (relative) recovery for phi and gamma respectively. Error analysis and comparisons with other investigators indicate that better than 2 m relative recovery was achieved at all sites. The data used were exclusively that from the estimated sites and included 18 orbital arcs which were less than two orbital revolutions in length, having successive tracks over the area. The techniques employed here, given their independence of global tracking support, can be effectively employed to improve various geodetic datums by providing very long and accurate baselines. The C-band data taken on GEOS-C should be employed to improve such geodetic datums as the European-1950 using similar techniques.

Collagen I Self-Assembly: Revealing the Developing Structures that Generate Turbidity

PubMed Central

Zhu, Jieling; Kaufman, Laura J.

2014-01-01

Type I collagen gels are routinely used in biophysical studies and bioengineering applications. The structural and mechanical properties of these fibrillar matrices depend on the conditions under which collagen fibrillogenesis proceeds, and developing a fuller understanding of this process will enhance control over gel properties. Turbidity measurements have long been the method of choice for monitoring developing gels, whereas imaging methods are regularly used to visualize fully developed gels. In this study, turbidity and confocal reflectance microscopy (CRM) were simultaneously employed to track collagen fibrillogenesis and reconcile the information reported by the two techniques, with confocal fluorescence microscopy (CFM) used to supplement information about early events in fibrillogenesis. Time-lapse images of 0.5 mg/ml, 1.0 mg/ml, and 2.0 mg/ml acid-solubilized collagen I gels forming at 27°C, 32°C, and 37°C were collected. It was found that in situ turbidity measured in a scanning transmittance configuration was interchangeable with traditional turbidity measurements using a spectrophotometer. CRM and CFM were employed to reveal the structures responsible for the turbidity that develops during collagen self-assembly. Information from CRM and transmittance images was collapsed into straightforward single variables; total intensity in CRM images tracked turbidity development closely for all collagen gels investigated, and the two techniques were similarly sensitive to fibril number and dimension. Complementary CRM, CFM, and in situ turbidity measurements revealed that fibril and network formation occurred before substantial turbidity was present, and the majority of increasing turbidity during collagen self-assembly was due to increasing fibril thickness. PMID:24739181

Analysis of dietary intake of selected metals in the NHEXAS-Maryland investigation.

PubMed Central

Ryan, P B; Scanlon, K A; MacIntosh, D L

2001-01-01

As part of a large pilot investigation of multimedia exposure to several classes of environmental contaminants, the National Human Exposure Assessment Survey (NHEXAS)-Maryland study, we collected 388 semiquantitative food checklists and duplicate diet solid food samples, analyzed for arsenic, cadmium, chromium, and lead concentrations, from 80 individuals in Maryland in 1995-1996 in a repeated measures design. Here we explore several methods to infer foods most strongly associated with concentrations of these metals observed in the duplicate diet in our data set. We employed two techniques in which logarithmically transformed metal concentrations in the duplicate diet were regressed on individual food item consumption using algorithms designed to identify the foods most associated with the observed duplicate diet concentrations. We also employed an alternative strategy in which foods to be used as independent variables in regression were selected using data collected in national food consumption and residue surveys, with regression procedures proceeding with the selected foods in a similar manner. The concordance of foods selected as major predictors among these three techniques is noteworthy and is discussed. Finally, the Dietary Exposure Potential Model (DEPM) was used with the Dietary Checklist data to predict duplicate diet concentrations within our sample. A comparison between the predicted values and those observed gave R(2) values of 0.180, 0.206, and 0.076 for As, Cd, and Pb, respectively (p < 0.0001 in all cases). We discuss the significance of these observations and the implications for dietary-exposure-based risk analysis and dietary intake epidemiology. PMID:11266320

Application of satellite data and LARS's data processing techniques to mapping vegetation of the Dismal Swamp. M.S. Thesis - Old Dominion Univ.

NASA Technical Reports Server (NTRS)

Messmore, J. A.

1976-01-01

The feasibility of using digital satellite imagery and automatic data processing techniques as a means of mapping swamp forest vegetation was considered, using multispectral scanner data acquired by the LANDSAT-1 satellite. The site for this investigation was the Dismal Swamp, a 210,000 acre swamp forest located south of Suffolk, Va. on the Virginia-North Carolina border. Two basic classification strategies were employed. The initial classification utilized unsupervised techniques which produced a map of the swamp indicating the distribution of thirteen forest spectral classes. These classes were later combined into three informational categories: Atlantic white cedar (Chamaecyparis thyoides), Loblolly pine (Pinus taeda), and deciduous forest. The subsequent classification employed supervised techniques which mapped Atlantic white cedar, Loblolly pine, deciduous forest, water and agriculture within the study site. A classification accuracy of 82.5% was produced by unsupervised techniques compared with 89% accuracy using supervised techniques.

Preimplantation bovine embryos: Pathobiology of Haemophilus somnus exposure and resistance mechanisms to vesicular stomatitis virus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thomson, M.S.

1988-01-01

Preimplantation bovine embryos were exposed in vitro to H. somnus to determine if the bacteria would adhere to zona pellucida-intact (ZP-I) embryos or adhere to or infect ZP-free embryos. The effect of H. somnus on embryonic development in vitro was also investigated. Electrophoretic comparisons of outer membrane proteins of H. somnus revealed 2 major protein bands common to 10 H. somnus isolates. A monoclonal antibody produced against the outer membrane proteins reacted to one of the major protein bands. The sensitivity of a nucleic acid probe for detection of vesicular stomatitis virus (VSV) was validated in cells in culture andmore » used to determine if the synthetic double-stranded complex of polyriboinosinic and polyribocytidylic acids (poly I:C) would induce viral resistance in cultured bovine embryos. Two {sup 32}P-nick translated probes of high specific activity prepared from plasmids containing nucleic acid sequences of VSV virus were employed for viral mRNA detection in the tissue culture cells using a DNA-hybridization dot-blot technique. Using one of the probes, the technique was applied to detect differences in viral replication between four groups of bovine embryos (nonexposed, exposed to VSV virus, poly I:C-treated, and poly I:C-treated and exposed to VSV). The nucleic acid probe was sufficiently sensitive to detect differences in quantities of VSV mRNA among embryo treatment groups, resulting in the demonstration that resistance to viral infection was induced in day 9 bovine embryos.« less

An Econometric Model for Forecasting Income and Employment in Hawaii.

ERIC Educational Resources Information Center

Chau, Laurence C.

This report presents the methodology for short-run forecasting of personal income and employment in Hawaii. The econometric model developed in the study is used to make actual forecasts through 1973 of income and employment, with major components forecasted separately. Several sets of forecasts are made, under different assumptions on external…

Employer Engagement within 14-19 Diploma Development

ERIC Educational Resources Information Center

Laczik, Andrea; White, Caroline

2009-01-01

In 2005, the UK government announced the development of a suite of employer-designed diplomas for 14-19 year olds linked to different industrial and commercial sectors. This article will reflect on some of the achievements and challenges of this major employer engagement initiative by drawing on three pieces of research: a review of Diploma…

Employer-Supported Child Care: Investing in Human Resources.

ERIC Educational Resources Information Center

Burud, Sandra L.; And Others

This book for employers interested in establishing child care programs is organized into five major topic areas. Part One provides an overview of employer-supported child care. Part Two discusses the processes of identifying and estimating benefits of child care to companies, and tax considerations. Part Three presents practical guidelines and a…

Insight into the Chemistry Skills Gap: The Duality between Expected and Desired Skills

ERIC Educational Resources Information Center

Kondo, Anne E.; Fair, Justin D.

2017-01-01

Results from an employer survey that examines the skills gap that exists for students majoring in chemistry are presented. Employers expect candidates with technical abilities but desire those who possess strong interprofessional skills. Although employers do not expect students to have had explicit teaching and application of interprofessional…

Good Work! Instructor's Guide. Revised. Employability Skills Series.

ERIC Educational Resources Information Center

Farrow, Douglas R.

This instructor's guide accompanies the student booklet/unit on good work habits/behaviors in the Employability Skills Series. (The student booklet is available separately as CE 031 161.) It first discusses the Employability Skills Series. A section on administering the unit details purpose of the unit and major concepts to be developed, lists…

Employers Roundtable: Employer Supported Child Care.

ERIC Educational Resources Information Center

Delaware Valley Child Care Council, Philadelphia, PA.

This booklet outlines a number of options available to employers to enable them to better cope with child care issues that they and their employees face. Major options include: (1) flexible work policies, such as flexible scheduling, alternate work places, shorter work weeks, and the consolidating of sick leave, holidays, and vacation time into…

Spouse Employment in the Army: Research Findings

DTIC Science & Technology

1990-03-01

Teplitzky, Thomas, & Nogami, 1988). In addition to being affected by the broader work-family issues which influence most employed wives, married women...resolve this important family issue . Procedure: A major effort of the Army Family Research Program (AFRP) has been the primary and secondary analyses...19 Spouse Earnings .......... ........................... .... 20 RELATED SPOUSE EMPLOYMENT ISSUES

Fair Employment and Performance Appraisal: Legal Requirements and Practical Guidelines.

ERIC Educational Resources Information Center

Edwards, Keith J.

The use of tests in personnel decisions has become an increasing legal liability for employers. The major questions raised by the courts concerning this use of tests are described. Current federal guidelines for performance appraisal systems, as established by the Equal Employment Opportunity Commission, are explained and traced to Title VII of…

University Education and Employment in Malaysia. IIEP Research Report No. 66.

ERIC Educational Resources Information Center

Aziz, Ungku A., Ed.; And Others

The role of university education in Malaysia in meeting the needs of the economy and employers was studied. To explore the relationship between education and employment, attention was focused on population characteristics, the labor market, the education system, and the economic system. Four major research concerns were: reasons for pursuing…

Some Aspects of Part-Time Work.

ERIC Educational Resources Information Center

Australian Dept. of Labour and National Service, Melbourne. Women's Bureau.

Of major importance to many married women seeking employment in Australia is the availability of part-time work. To describe the economic aspects of part-time employment for women, a review was made of statistics published by the Commonwealth Bureau of Census and Statistics and of research on part-time employment in overseas countries, and a…

Employer Interest in Child Care Growing and Diversifying.

ERIC Educational Resources Information Center

Neugebauer, Roger

1993-01-01

Continuing employer interest in child care reflects the fact that child care is still a major concern for employees. Discusses trends related to the positive results of child care; the leading role of bigger companies; employers' concerns regarding equity, liability, and cost; a more diversified response to meeting employees' child-care needs; and…

Return to Work and Social Communication Ability Following Severe Traumatic Brain Injury

ERIC Educational Resources Information Center

Douglas, Jacinta M.; Bracy, Christine A.; Snow, Pamela C.

2016-01-01

Purpose: Return to competitive employment presents a major challenge to adults who survive traumatic brain injury (TBI). This study was undertaken to better understand factors that shape employment outcome by comparing the communication profiles and self-awareness of communication deficits of adults who return to and maintain employment with those…

1963 Vajont rock slide: a comparison between 3D DEM and 3D FEM

NASA Astrophysics Data System (ADS)

Crosta, Giovanni; Utili, Stefano; Castellanza, Riccardo; Agliardi, Federico; Bistacchi, Andrea; Weng Boon, Chia

2013-04-01

Data on the exact location of the failure surface of the landslide have been used as the starting point for the modelling of the landslide. 3 dimensional numerical analyses were run employing both the discrete element method (DEM) and a Finite Element Method (FEM) code. In this work the focus is on the prediction of the movement of the landlside during its initial phase of detachment from Mount Toc. The results obtained by the two methods are compared and conjectures on the observed discrepancies of the predictions between the two methods are formulated. In the DEM simulations the internal interaction of the sliding blocks and the expansion of the debris is obtained as a result of the kinematic interaction among the rock blocks resulting from the jointing of the rock mass involved in the slide. In the FEM analyses, the c-phi reduction technique was employed along the predefine failure surface until the onset of the landslide occurred. In particular, two major blocks of the landslide were identified and the stress, strain and displacement fields at the interface between the two blocks were analysed in detail.

The radiographic assessment of spinal flexibility in scoliosis: a study of the efficacy of the prone push film.

PubMed

Kleinman, R G; Csongradi, J J; Rinksy, L A; Bleck, E E

1982-01-01

The use of a "prone push" posteroanterior radiograph of the spine was reviewed in 58 patients with scoliosis (82 curves) who underwent Harrington instrumentation and spinal fusion. The technique is previously undescribed and is accomplished by applying manual pressure to the apices of each curve with the patient prone on the X-ray table. The average correction obtained for all 82 curves was 21.1 degrees, as measured on the push films and 21.8 degrees postoperatively. The difference between these values was not statistically significant. The close relationship between push film and immediate postoperative correction was not altered by the location of the curve, the sex or age of the patient, the presence of a single- or double-major curve pattern, the type of instrumentation employed, nor the etiology of the scoliosis. This method is an alternative to the commonly employed supine lateral bending radiographs. An estimate of spinal flexibility is important for determination of structural change in the spine, the rigidity of curves considered for instrumentation, the curves requiring fusion, the length of fusion necessary, and the amount of correction that is safely possible.

Expectations and limitations due to brachial plexus injury: a qualitative study.

PubMed

Mancuso, Carol A; Lee, Steve K; Dy, Christopher J; Landers, Zoe A; Model, Zina; Wolfe, Scott W

2015-12-01

This study described physical and psychosocial limitations associated with adult brachial plexus injuries (BPI) and patients' expectations of BPI surgery. During in-person interviews, preoperative patients were asked about expectations of surgery and preoperative and postoperative patients were asked about limitations due to BPI. Postoperative patients also rated improvement in condition after surgery. Data were analyzed with qualitative and quantitative techniques. Ten preoperative and 13 postoperative patients were interviewed; mean age was 37 years, 19 were men, all were employed/students, and most injuries were due to trauma. Preoperative patients cited several main expectations, including pain-related issues, and improvement in arm movement, self-care, family interactions, and global life function. Work-related expectations were tailored to employment type. Preoperative and postoperative patients reported that pain, altered sensation, difficulty managing self-care, becoming physically and financially dependent, and disability in work/school were major issues. All patients reported making major compensations, particularly using the uninjured arm. Most reported multiple mental health effects, were distressed with long recovery times, were self-conscious about appearance, and avoided public situations. Additional stresses were finding and paying for BPI surgery. Some reported BPI impacted overall physical health, life priorities, and decision-making processes. Four postoperative patients reported hardly any improvement, four reported some/a good deal, and five reported a great deal of improvement. BPI is a life-altering event affecting physical function, mental well-being, financial situation, relationships, self-image, and plans for the future. This study contributes to clinical practice by highlighting topics to address to provide comprehensive BPI patient-centered care.

Workers at Risk: Increased Numbers in Contingent Employment Lack Insurance, Other Benefits

DTIC Science & Technology

1991-03-01

self-employed, leased employees , and workers in the business services sector.- Estimates of the size, composition, and impact of the contingent work...government, and workers . The majority of workers receive health , pension, or other fringe benefits through their employers. Government and employers provide...who head families, have fewer economic protections than full-time permanent employees . Part-time and temporary workers generally receive lower pay

Higher Education and Employment: The Changing Relationship. The Case of the Humanities and Social Sciences. Expert Contribution: Norway. The Humanities, Social Sciences and Employment.

ERIC Educational Resources Information Center

Eide, Kjell

This report, one of a series of country studies on higher education and employment, particularly in the humanities and social sciences, looks at the employment of social science and humanities graduates in Norway. The paper opens by briefly sketching some major interrelated developments in current society such as shifts in the economy, changes in…

Disability, gender, and employment relationships in Africa: The case of Ghana

PubMed Central

2015-01-01

The exploratory quantitative study sought to develop an understanding about the relationships among disability, gender and employment in Northern Ghana. A total of 110 individuals with disabilities (20–60 years) from various disability groups participated in the study. The results indicate that many persons with disabilities are unemployed, the majority being women. Discrimination is cited as the greatest barrier to the employment of persons with disabilities, particularly women. The majority of persons with disabilities, typically women, live in poverty; given that some are unemployed and those who are employed worked mostly in marginal, seasonal and menial jobs. Persons with disabilities also experience several challenges on the job, including negative perceptions about their capabilities, discrimination and exclusion, irrespective of the employment sector and disability type. Educational interventions such as workshops, documenting and showcasing success stories of persons with disabilities could be helpful to reduce negative perceptions about their capabilities as well as discrimination against them. Government intervention to support persons with disabilities with start-up capital and funding for formal education is also recommended as these two elements were identified respectively as barriers to self-employment and employment in the public/private sectors. Government interventions to create educational opportunities for persons with disabilities are essential given that lower educational attainment affect their employment. PMID:28730017

Disability, gender, and employment relationships in Africa: The case of Ghana.

PubMed

Naami, Augustina

2015-01-01

The exploratory quantitative study sought to develop an understanding about the relationships among disability, gender and employment in Northern Ghana. A total of 110 individuals with disabilities (20-60 years) from various disability groups participated in the study. The results indicate that many persons with disabilities are unemployed, the majority being women. Discrimination is cited as the greatest barrier to the employment of persons with disabilities, particularly women. The majority of persons with disabilities, typically women, live in poverty; given that some are unemployed and those who are employed worked mostly in marginal, seasonal and menial jobs. Persons with disabilities also experience several challenges on the job, including negative perceptions about their capabilities, discrimination and exclusion, irrespective of the employment sector and disability type. Educational interventions such as workshops, documenting and showcasing success stories of persons with disabilities could be helpful to reduce negative perceptions about their capabilities as well as discrimination against them. Government intervention to support persons with disabilities with start-up capital and funding for formal education is also recommended as these two elements were identified respectively as barriers to self-employment and employment in the public/private sectors. Government interventions to create educational opportunities for persons with disabilities are essential given that lower educational attainment affect their employment.

The analytical representation of viscoelastic material properties using optimization techniques

NASA Technical Reports Server (NTRS)

Hill, S. A.

1993-01-01

This report presents a technique to model viscoelastic material properties with a function of the form of the Prony series. Generally, the method employed to determine the function constants requires assuming values for the exponential constants of the function and then resolving the remaining constants through linear least-squares techniques. The technique presented here allows all the constants to be analytically determined through optimization techniques. This technique is employed in a computer program named PRONY and makes use of commercially available optimization tool developed by VMA Engineering, Inc. The PRONY program was utilized to compare the technique against previously determined models for solid rocket motor TP-H1148 propellant and V747-75 Viton fluoroelastomer. In both cases, the optimization technique generated functions that modeled the test data with at least an order of magnitude better correlation. This technique has demonstrated the capability to use small or large data sets and to use data sets that have uniformly or nonuniformly spaced data pairs. The reduction of experimental data to accurate mathematical models is a vital part of most scientific and engineering research. This technique of regression through optimization can be applied to other mathematical models that are difficult to fit to experimental data through traditional regression techniques.

Unemployment in the United States After Traumatic Brain Injury for Working-Age Individuals: Prevalence and Associated Factors 2 Years Postinjury

PubMed Central

Cuthbert, Jeffrey P.; Harrison-Felix, Cynthia; Corrigan, John D.; Bell, Jeneita M.; Haarbauer-Krupa, Juliet K.; Miller, A. Cate

2017-01-01

Objective To estimate the prevalence of unemployment and part-time employment in the United States for working-age individuals completing rehabilitation for a primary diagnosis of traumatic brain injury (TBI) between 2001 and 2010. Design Secondary data analysis. Setting Acute inpatient rehabilitation facilities. Participants Patients aged 16 to 60 years at injury who completed inpatient rehabilitation for TBI between 2001 and 2010. Main Outcome Measures Unemployment; Part-time employment. Results The prevalence of unemployment for persons in the selected cohort was 60.4% at 2-year postinjury. Prevalence of unemployment at 2-year postinjury was significantly associated with the majority of categories of age group, race, gender, marital status, primary inpatient rehabilitation payment source, education, preinjury vocational status, length of stay, and Disability Rating Scale. The direction of association for the majority of these variables complement previous research in this area, with only Hispanic ethnicity and the FIM Cognitive subscale demonstrating disparate findings. For those employed at 2-year postinjury, the prevalence of part-time employment was 35.0%. The model of prevalence for part-time employment at 2-year postinjury was less robust, with significant relationships with some categorical components of age group, gender, marital status, primary payment source, preinjury vocational status, and Disability Rating Scale. Conclusions The prevalence of unemployment for patients completing inpatient rehabilitation for TBI was substantial (60.4%). The majority of factors found to associate with 2 years’ unemployment were complementary of previously published research; however, these were often smaller in magnitude than previous reports. The prevalence of part-time employment was also an issue for this cohort and included 35.0% of all employed individuals. In regard to the determination of factors associated with part-time employment, additional analyses that include more fine-grained factors associated with employment, including physical and psychosocial functioning, are recommended. PMID:25955703

Establishing a legal service for major trauma patients at a major trauma centre in the UK.

PubMed

Seligman, William H; Thompson, Julian; Thould, Hannah E; Tan, Charlotte; Dinsmore, Andrew; Lockey, David J

2017-09-01

Major trauma causes unanticipated critical illness and patients have often made few arrangements for what are sudden and life-changing circumstances. This can lead to financial, housing, insurance, legal and employment issues for patients and their families.A UK law firm worked with the major trauma services to develop a free and comprehensive legal service for major trauma patients and their families at a major trauma centre (MTC) in the UK. In 2013, a legal service was established at North Bristol NHS Trust. Referrals are made by trauma nurse practitioners and it operates within a strict ethical framework. A retrospective analysis of the activity of this legal service between September 2013 and October 2015 was undertaken. 66 major trauma patients were seen by the legal teams at the MTC. 535 hours of free legal advice were provided on non-compensation issues-an average of 8 hours per patient. This initiative confirms a demand for the early availability of legal advice for major trauma patients to address a range of non-compensation issues as well as for identification of potential compensation claims. The availability of advice at the MTC is convenient for relatives who may be spending the majority of their time with injured relatives in hospital. More data are needed to establish the rehabilitation and health effects of receiving non-compensation advice after major injury; however, the utilisation of this service suggests that it should be considered at the UK MTCs. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Pressure- and Temperature-Sensitive Paint at 0.3-m Transonic Cryogenic Tunnel

NASA Technical Reports Server (NTRS)

Watkins, A. Neal; Leighty, Bradley D.; Lipford, William E.; Goodman, Kyle Z.

2015-01-01

Recently both Pressure- and Temperature-Sensitive Paint experiments were conducted at cryogenic conditions in the 0.3-m Transonic Cryogenic Tunnel at NASA Langley Research Center. This represented a re-introduction of the techniques to the facility after more than a decade, and provided a means to upgrade the measurements using newer technology as well as demonstrate that the techniques were still viable in the facility. Temperature-Sensitive Paint was employed on a laminar airfoil for transition detection and Pressure-Sensitive Paint was employed on a supercritical airfoil. This report will detail the techniques and their unique challenges that need to be overcome in cryogenic environments. In addition, several optimization strategies will also be discussed.

Novel laser gain and time-resolved FTIR studies of photochemistry

NASA Technical Reports Server (NTRS)

Leone, Stephen R.

1990-01-01

Several techniques are discussed which can be used to explore laboratory photochemical processes and kinetics relevant to planetary atmospheres; these include time-resolved laser gain-versus-absorption spectroscopy and time-resolved Fourier transform infrared (FTIR) emission studies. The laser gain-versus-absorption method employed tunable diode and F-center lasers to determine the yields of excited photofragments and their kinetics. The time-resolved FTIR technique synchronizes the sweep of a commercial FTIR with a pulsed source of light to obtain emission spectra of novel transient species in the infrared. These methods are presently being employed to investigate molecular photodissociation, the yields of excited states of fragments, their subsequent reaction kinetics, Doppler velocity distributions, and velocity-changing collisions of translationally fast atoms. Such techniques may be employed in future investigations of planetary atmospheres, for example to study polycyclic aromatic hydrocarbons related to cometary emissions, to analyze acetylene decomposition products and reactions, and to determine spectral features in the near infrared and infrared wavelength regions for planetary molecules and clusters.

Building Jobs, Rebuilding Lives: Placing Ex-Offenders with Employers in the Residential and Light Commercial Construction Industry.

ERIC Educational Resources Information Center

Home Builders Inst., Washington, DC.

This guide presents a focused, structured method of facilitating ex-offender employment. Section 1 takes classic marketing techniques and adapts them to the needs of the particular situation, placing ex-offenders in meaningful employment. The set of specific requirements for creating a workable marketing plan is condensed to six basic steps that…

Combinative Particle Size Reduction Technologies for the Production of Drug Nanocrystals

PubMed Central

Salazar, Jaime; Müller, Rainer H.; Möschwitzer, Jan P.

2014-01-01

Nanosizing is a suitable method to enhance the dissolution rate and therefore the bioavailability of poorly soluble drugs. The success of the particle size reduction processes depends on critical factors such as the employed technology, equipment, and drug physicochemical properties. High pressure homogenization and wet bead milling are standard comminution techniques that have been already employed to successfully formulate poorly soluble drugs and bring them to market. However, these techniques have limitations in their particle size reduction performance, such as long production times and the necessity of employing a micronized drug as the starting material. This review article discusses the development of combinative methods, such as the NANOEDGE, H 96, H 69, H 42, and CT technologies. These processes were developed to improve the particle size reduction effectiveness of the standard techniques. These novel technologies can combine bottom-up and/or top-down techniques in a two-step process. The combinative processes lead in general to improved particle size reduction effectiveness. Faster production of drug nanocrystals and smaller final mean particle sizes are among the main advantages. The combinative particle size reduction technologies are very useful formulation tools, and they will continue acquiring importance for the production of drug nanocrystals. PMID:26556191

Multigrid Strategies for Viscous Flow Solvers on Anisotropic Unstructured Meshes

NASA Technical Reports Server (NTRS)

Movriplis, Dimitri J.

1998-01-01

Unstructured multigrid techniques for relieving the stiffness associated with high-Reynolds number viscous flow simulations on extremely stretched grids are investigated. One approach consists of employing a semi-coarsening or directional-coarsening technique, based on the directions of strong coupling within the mesh, in order to construct more optimal coarse grid levels. An alternate approach is developed which employs directional implicit smoothing with regular fully coarsened multigrid levels. The directional implicit smoothing is obtained by constructing implicit lines in the unstructured mesh based on the directions of strong coupling. Both approaches yield large increases in convergence rates over the traditional explicit full-coarsening multigrid algorithm. However, maximum benefits are achieved by combining the two approaches in a coupled manner into a single algorithm. An order of magnitude increase in convergence rate over the traditional explicit full-coarsening algorithm is demonstrated, and convergence rates for high-Reynolds number viscous flows which are independent of the grid aspect ratio are obtained. Further acceleration is provided by incorporating low-Mach-number preconditioning techniques, and a Newton-GMRES strategy which employs the multigrid scheme as a preconditioner. The compounding effects of these various techniques on speed of convergence is documented through several example test cases.

Neural net diagnostics for VLSI test

NASA Technical Reports Server (NTRS)

Lin, T.; Tseng, H.; Wu, A.; Dogan, N.; Meador, J.

1990-01-01

This paper discusses the application of neural network pattern analysis algorithms to the IC fault diagnosis problem. A fault diagnostic is a decision rule combining what is known about an ideal circuit test response with information about how it is distorted by fabrication variations and measurement noise. The rule is used to detect fault existence in fabricated circuits using real test equipment. Traditional statistical techniques may be used to achieve this goal, but they can employ unrealistic a priori assumptions about measurement data. Our approach to this problem employs an adaptive pattern analysis technique based on feedforward neural networks. During training, a feedforward network automatically captures unknown sample distributions. This is important because distributions arising from the nonlinear effects of process variation can be more complex than is typically assumed. A feedforward network is also able to extract measurement features which contribute significantly to making a correct decision. Traditional feature extraction techniques employ matrix manipulations which can be particularly costly for large measurement vectors. In this paper we discuss a software system which we are developing that uses this approach. We also provide a simple example illustrating the use of the technique for fault detection in an operational amplifier.

A double-tracer technique to characterize absorption, distribution, metabolism and excretion (ADME) of [14C]-basimglurant and absolute bioavailability after oral administration and concomitant intravenous microdose administration of [13C6]-labeled basimglurant in humans.

PubMed

Guerini, Elena; Schadt, Simone; Greig, Gerard; Haas, Ruth; Husser, Christophe; Zell, Manfred; Funk, Christoph; Hartung, Thomas; Gloge, Andreas; Mallalieu, Navita L

2017-02-01

1. The emerging technique of employing intravenous microdose administration of an isotope tracer concomitantly with an [ 14 C]-labeled oral dose was used to characterize the disposition and absolute bioavailability of a novel metabotropic glutamate 5 (mGlu5) receptor antagonist under clinical development for major depressive disorder (MDD). 2. Six healthy volunteers received a single 1 mg [ 12 C/ 14 C]-basimglurant (2.22 MBq) oral dose and a concomitant i.v. tracer dose of 100 μg of [ 13 C 6 ]-basimglurant. Concentrations of [ 12 C]-basimglurant and the stable isotope [ 13 C 6 ]-basimglurant were determined in plasma by a specific LC/MS-MS method. Total [ 14 C] radioactivity was determined in whole blood, plasma, urine and feces by liquid scintillation counting. Metabolic profiling was conducted in plasma, urine, blood cell pellet and feces samples. 3. The mean absolute bioavailability after oral administration (F) of basimglurant was ∼67% (range 45.7-77.7%). The major route of [ 14 C]-radioactivity excretion, primarily in form of metabolites, was in urine (mean recovery 73.4%), with the remainder excreted in feces (mean recovery 26.5%). The median t max for [ 12 C]-basimglurant after the oral administration was 0.71 h (range 0.58-1.00) and the mean terminal half-life was 77.2 ± 38.5 h. Terminal half-life for the [ 14 C]-basimglurant was 178 h indicating presence of metabolites with a longer terminal half-life. Five metabolites were identified with M1-Glucuronide as major and the others in trace amounts. There was minimal binding of drug to RBCs. IV pharmacokinetics was characterized with a mean ± SD CL of 11.8 ± 7.4 mL/h and a Vss of 677 ± 229 L. 4. The double-tracer technique used in this study allowed to simultaneously characterize the absolute bioavailability and disposition characteristics of the new oral molecular entity in a single study.

Efficient sweep buffering in swept source optical coherence tomography using a fast optical switch

PubMed Central

Dhalla, Al-Hafeez; Shia, Kevin; Izatt, Joseph A.

2012-01-01

We describe a novel buffering technique for increasing the A-scan rate of swept source optical coherence tomography (SSOCT) systems employing low duty cycle swept source lasers. This technique differs from previously reported buffering techniques in that it employs a fast optical switch, capable of switching in 60 ns, instead of a fused fiber coupler at the end of the buffering stage, and is therefore appreciably more power efficient. The use of the switch also eliminates patient exposure to light that is not used for imaging that occurs at the end of the laser sweep, thereby increasing the system sensitivity. We also describe how careful management of polarization can remove undesirable artifacts due to polarization mode dispersion. In addition, we demonstrate how numerical compensation techniques can be used to modify the signal from a Mach-Zehnder interferometer (MZI) clock obtained from the original sweep to recalibrate the buffered sweep, thereby reducing the complexity of systems employing lasers with integrated MZI clocks. Combining these methods, we constructed an SSOCT system employing an Axsun technologies laser with a sweep rate of 100kHz and 6dB imaging range of 5.5mm. The sweep rate was doubled with sweep buffering to 200 kHz, and the imaging depth was extended to 9 mm using coherence revival. We demonstrated the feasibility of this system by acquiring images of the anterior segments and retinas of healthy human volunteers. PMID:23243559

Efficient sweep buffering in swept source optical coherence tomography using a fast optical switch.

PubMed

Dhalla, Al-Hafeez; Shia, Kevin; Izatt, Joseph A

2012-12-01

We describe a novel buffering technique for increasing the A-scan rate of swept source optical coherence tomography (SSOCT) systems employing low duty cycle swept source lasers. This technique differs from previously reported buffering techniques in that it employs a fast optical switch, capable of switching in 60 ns, instead of a fused fiber coupler at the end of the buffering stage, and is therefore appreciably more power efficient. The use of the switch also eliminates patient exposure to light that is not used for imaging that occurs at the end of the laser sweep, thereby increasing the system sensitivity. We also describe how careful management of polarization can remove undesirable artifacts due to polarization mode dispersion. In addition, we demonstrate how numerical compensation techniques can be used to modify the signal from a Mach-Zehnder interferometer (MZI) clock obtained from the original sweep to recalibrate the buffered sweep, thereby reducing the complexity of systems employing lasers with integrated MZI clocks. Combining these methods, we constructed an SSOCT system employing an Axsun technologies laser with a sweep rate of 100kHz and 6dB imaging range of 5.5mm. The sweep rate was doubled with sweep buffering to 200 kHz, and the imaging depth was extended to 9 mm using coherence revival. We demonstrated the feasibility of this system by acquiring images of the anterior segments and retinas of healthy human volunteers.

Boosting production yield of biomedical peptides

NASA Technical Reports Server (NTRS)

Manatt, S. L.

1978-01-01

Nuclear magnetic resonance (NMR) technique is employed to monitor synthesis of biomedical peptides. Application of NMR technique may improve production yields of insulin, ACTH, and growth hormones, as well as other synthesized biomedical peptides.

Microscale Titration in Schools Titration Competition.

ERIC Educational Resources Information Center

Clark, Michael J.

1998-01-01

Reviews the requirements of the National Titration Competition and describes how a team in a local competition used the technique. Compares microscale titration to conventional titration. Outlines the benefits of employing microscale techniques. (DDR)

Monitoring Air Quality with Leaf Yeasts.

ERIC Educational Resources Information Center

Richardson, D. H. S.; And Others

1985-01-01

Proposes that leaf yeast serve as quick, inexpensive, and effective techniques for monitoring air quality. Outlines procedures and provides suggestions for data analysis. Includes results from sample school groups who employed this technique. (ML)

The efficacy of manual joint mobilisation/manipulation in treatment of lateral ankle sprains: a systematic review.

PubMed

Loudon, Janice K; Reiman, Michael P; Sylvain, Jonathan

2014-03-01

Lateral ankle sprains are common and can have detrimental consequences to the athlete. Joint mobilisation/manipulation may limit these outcomes. Systematically summarise the effectiveness of manual joint techniques in treatment of lateral ankle sprains. This review employed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A computer-assisted literature search of MEDLINE, CINHAL, EMBASE, OVID and Physiotherapy Evidence Database (PEDro) (January 1966 to March 2013) was used with the following keywords alone and in combination 'ankle', 'sprain', 'injuries', 'lateral', 'manual therapy', and 'joint mobilisation'. The methodological quality of individual studies was assessed using the PEDro scale. After screening of titles, abstracts and full articles, eight articles were kept for examination. Three articles achieved a score of 10 of 11 total points; one achieved a score of 9; two articles scored 8; one article scored a 7 and the remaining article scored a 5. Three articles examined joint techniques for acute sprains and the remainder examined subacute/chronic ankle sprains. Outcome measures included were pain level, ankle range of motion, swelling, functional score, stabilometry and gait parameters. The majority of the articles only assessed these outcome measures immediately after treatment. No detrimental effects from the joint techniques were revealed in any of the studies reviewed. For acute ankle sprains, manual joint mobilisation diminished pain and increased dorsiflexion range of motion. For treatment of subacute/chronic lateral ankle sprains, these techniques improved ankle range-of-motion, decreased pain and improved function.

An update on auricular reconstruction: three major auricular malformations of microtia, prominent ear and cryptotia.

PubMed

Park, Chul; Yoo, Yeon-Sik; Hong, Sung-Taek

2010-12-01

Microtia, prominent ear, and cryptotia are the most common types of auricular malformations. This review provides updated information on these types of reconstructions, in addition to recalling previously accepted surgical methods. Autogenous costal cartilage is still considered as an ideal material for framework fabrication in microtia reconstruction. Many surgeons have adopted the Nagata approach, the Brent approach, or variations of the two, in their work. With these employed techniques, auricles reconstructed by experienced surgeons have proven to be aesthetically promising. However, with regards to the harvesting of the costal cartilage, the underdevelopment of the chest wall donor site, alopecia of the scalp, and scarring of the postauricular-mastoid region are still considered problematic aspects of these approaches. Some articles have described attempts to solve these problems, whereas some experiments in cartilage production using tissue engineering techniques have shown promise in their initial stages of development.It is generally accepted that prominent ears should be corrected through a combination of sculpting and suture techniques, according to the individual shape and the quality of the ear prominence.Most of the cryptotia malformations show not only embedded upper auricles, but also associated adhesions of the upper auricular cartilage. Their correction should therefore resolve both deformities. A number of articles highlighting clinical experiences with auricular reconstructions for microtia, prominent ear, and cryptotia have been included in this review. We believe that the information synthesized here will become a basis for further development of auricular reconstruction techniques.

Questions, Questioning Techniques, and Effective Teaching.

ERIC Educational Resources Information Center

Wilen, William W., Ed.

This book focuses on questioning techniques and strategies teachers may employ to make the difference between active and passive learning in the classroom. There are nine chapters: (1) Why Questions? (Ambrose A. Clegg, Jr.); (2) Review of Research on Questioning Techniques (Meredith D. Gall and Tom Rhody); (3) The Multidisciplinary World of…

Representation of Knowledge on Some Management Accounting Techniques in Textbooks

ERIC Educational Resources Information Center

Golyagina, Alena; Valuckas, Danielius

2016-01-01

This paper examines the coverage of management accounting techniques in several popular management accounting texts, assessing each technique's claimed position within practice, its benefits and limitations, and the information sources substantiating these claims. Employing the notion of research genres, the study reveals that textbooks in their…

A national survey of psychosocial job stressors and their implications for health among working people in Taiwan.

PubMed

Cheng, Y; Guo, Y L; Yeh, W Y

2001-09-01

The prevalence of job stress, distributions of major job stressors, and the associations of job stress with multiple self-reported health complaints were examined in a national survey conducted in 1994 in Taiwan. A total of 9,746 men and 5,599 women who were employed at the time of the survey and aged between 25 and 65-years were studied. Information on employment status, perceived level of job stress, major job stressors, and health complaints were obtained by a self-administered questionnaire. Overall, 7.6% of men and 6.5% of women reported often or always feeling very stressed at work. Higher levels of perceived job stress were found among subjects who were younger, with higher education level, working in a larger firm, working for longer hours per week, and who were administrators or managers. Problems with individual job content were ranked as the most important job stressor in men across all employment categories and in most women. Other major job stressors included problems with monetary rewards and lack of career prospects. The patterns of major job stressors appear to vary by employment grade and by gender. After adjustment for age and education, employees who perceived higher levels of job stress had significantly increased risks of multiple health problems, including strained eyes, ringing ears, chronic cough with phlegm, chest tightness. stomach problems, headache, and musculoskeletal discomfort. These results suggest that psychosocial stress in the workplace has profound impacts on health. This study identified high-risk groups and major types of job stressors for further investigation.

Employers, workers, and the future of employment-based health benefits.

PubMed

Blakely, Stephen

2010-02-01

EBRI'S BIANNUAL POLICY FORUM: This Issue Brief summarizes presentations at EBRI's 65th biannual policy forum, held in Washington, DC, on Dec. 10, 2009, on the topic, "Employers, Workers, and the Future of Employment-Based Health Benefits." The forum brought together a wide range of economic, benefits, management, and labor experts to share their expertise at a time when major health reform legislation was being debated in Congress. The focus: How might this affect the way that the vast majority of Americans currently get their health insurance coverage? THE EMPLOYMENT-BASED HEALTH INSURANCE SYSTEM: Most people who have health insurance coverage in the United States get it through their job: In 2008, about 61 percent of the nonelderly population had employment-based health benefits, 19 percent were covered by public programs, 6 percent had individual coverage, and 17 percent were uninsured. Not surprisingly, given the deep conflicts that exist over President Obama's health reform plan and the different bills that have passed the House and Senate, benefits experts also do not agree on what "health reform" will mean for either workers or employers. Views ranged from "Will anyone notice?" to predictions of great upheaval for workers and their employers, patients and health care providers, and the entire U.S. health care system. One point of consensus among both labor and management representatives: Imposing a tax on health benefits is likely to cause major cuts in health benefits and might result in structural changes in the employment-based benefits system. A common disappointment voiced at the forum was that the initial effort to reform the delivery and cost of health care in America gradually became focused on just financing and coverage of health insurance. The ever-rising cost of health insurance affects different employers and workers in different ways--with small employers and low-wage workers being the most disadvantaged. With health premiums having risen almost five times as much as the overall rate of inflation since 2000, employers face unsustainable cost increases in health benefits. For a minimum-wage worker, the cost of family coverage (averaging about $13,700 a year in a small firm) exceeds their total annual income (about $11,500 a year). Small employers, if they offer health benefits at all, pay proportionately more than large employers for the same health coverage. As reflected by the debate in Congress, the American public has conflicted opinions on both the U.S. health care system and on reform: Surveys find that people tend to be satisfied with the quality of their own care but not with costs and access, and a majority rates the system as fair or poor. Opinions divide sharply along partisan lines. While large employers tend to express continued commitment to health benefits, small employers see themselves strongly disadvantaged by the current system. Consultants report many employers privately want to drop benefits to control costs, but realize there are risks to doing so and none wants to be first. Employers express strong interest in wellness and disease management programs as a way to control costs, even though some experts say there is no evidence these work. Consumer-driven health plans are expected to continue their slow rate of growth.

Employer Engagement with the Vocational Education and Training System in Australia. Occasional Paper

ERIC Educational Resources Information Center

Stanwick, John

2009-01-01

This paper is a review of literature on employer engagement with vocational education and training (VET). The main conclusion is that the major form of engagement is through the competency-based training system, which is manifested through training packages. Another way employers are encouraged to engage with VET is through competition amongst…

Who Gets the Job? First-Generation College Students' Perceptions of Employer Screening Methods

ERIC Educational Resources Information Center

Parks-Yancy, Rochelle; Cooley, Delonia

2018-01-01

What are first-generation college students' (FGCS) perspectives of employment screening methods? The authors investigate which methods FGCS believe are likely to cause an employer to extend a job offer and which methods yield the best pool of job applicants. Survey data were collected from undergraduate business majors. They were analyzed using…

The Employment and Unemployment of Women in OECD Countries.

ERIC Educational Resources Information Center

Paukert, Liba

This report examines the major trends in women's employment and unemployment over the past two decades in Organisation for Economic Co-operation and Development member countries. Employment and unemployment trends in the labor force by sex are first considered. The report next examines the growth of the female labor supply and the trends in the…

Career and Employment Counseling in Canada: The State of the Art. ERIC Digest.

ERIC Educational Resources Information Center

Hiebert, Bryan; Conger, Stu

A major survey of career and employment counseling in Canada was completed in 1993, with over 1600 counselors, department heads and managers of counseling centers, and regional directors working in career and employment counseling centers being polled. Survey results indicated: (1) there is a strong need for evaluation in all aspects of career…

Freedom from Want: Towards More Equality. Proceedings of the Conference on Income Maintenance and Full Employment.

ERIC Educational Resources Information Center

Thode, Kathleen B., Ed.

The document reports on a 1976 conference discussing critical issues related to income maintenance and full employment. The objective is to explore the persistence of inequality and want in America and the issue of achieving more equality through income maintenance programs and full employment. Major topics include values issues; income…

Employers and Child Care: Development of a New Employee Benefit. A BNA Special Report.

ERIC Educational Resources Information Center

Bureau of National Affairs, Inc., Washington, DC.

Written primarily from the employer's perspective, this report examines the issues involved in providing child care assistance as an employee benefit. Chapter 1 summarizes rapid changes in the work force that have produced employer involvement in child care arrangements. The major findings of the report are highlighted in Chapter 2, including the…

School to Employment Program (STEP) Jobs for Youth. Annual Report.

ERIC Educational Resources Information Center

New York State Dept. of Labor, Albany.

The School to Employment Program (STEP) provided job placement, training, counseling, and remediation for economically disadvantaged youth aged 14-21 who were at risk of dropping out of school or who had dropped out and were unprepared for employment. Its two major components were in-school and out-of-school programs. Youth in both programs were…

A Pilot Study for Gainful Employment in Home Economics. Final Report. Volume I.

ERIC Educational Resources Information Center

Cozine, June; And Others

The major purpose of the study was to develop and test curriculum materials for three entry level gainful employment courses: Child Care Services, Clothing Services, Food Services. A second objective was to formulate recommendations for policies and procedures to follow in initiating and developing gainful employment programs in home economics.…

Building a Nation That Works: Designing TANF for the Workplace.

ERIC Educational Resources Information Center

Jobs for the Future, Boston, MA.

Temporary Assistance to Needy Families (TANF) needs to focus more directly on what happens in the workplace and consider the needs of employers. Employers identify skill levels of both job applicants and employees as a major obstacle to employing and retaining TANF recipients and other entry-level workers as well as the cost of entry-level…

Tailoring Modified Moore Method Techniques to Liberal Arts Mathematics Courses

ERIC Educational Resources Information Center

Hitchman, Theron J.; Shaw, Douglas

2015-01-01

Inquiry-based learning (IBL) techniques can be used in mathematics courses for non-majors, such as courses required for liberal arts majors to fulfill graduation requirements. Unique challenges are discussed, followed by adaptations of IBL techniques to overcome those challenges.

Multiple Employment Training Programs. Major Overhaul Is Needed. Testimony before the Subcommittee on Employment, Housing, and Aviation, Committee on Government Operations, House of Representatives. Agencies Do Not Know If Their Programs Are Working Effectively.

ERIC Educational Resources Information Center

Crawford, Clarence C.

At least 154 employment training programs (ETP) providing approximately $25 billion in employment training assistance are currently administered by 14 federal agencies. Individually, these programs are all well-intended. Collectively, however, they have been described as bewildering and frightening to clients and confusing to those who operate…

47 CFR 22.321 - Equal employment opportunities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... employment advertisements in media which have significant circulation among minority groups in the recruiting area. (D) Recruiting through schools and colleges with significant minority group enrollments. (E... selection techniques or tests that have the effect of discriminating against minority groups or females...

Concurrent validation of a neurocognitive assessment protocol for clients with mental illness in job matching as shop sales in supported employment.

PubMed

Ng, S S W; Lak, D C C; Lee, S C K; Ng, P P K

2015-03-01

Occupational therapists play a major role in the assessment and referral of clients with severe mental illness for supported employment. Nonetheless, there is scarce literature about the content and predictive validity of the process. In addition, the criteria of successful job matching have not been analysed and job supervisors have relied on experience rather than objective standards in recruitment. This study aimed to explore the profile of successful clients working in 'shop sales' in a supportive environment using a neurocognitive assessment protocol, and to validate the protocol against 'internal standards' of the job supervisors. This was a concurrent validation study of criterion-related scales for a single job type. The subjective ratings from the supervisors were concurrently validated against the results of neurocognitive assessment of intellectual function and work-related cognitive behaviour. A regression model was established for clients who succeeded and failed in employment using supervisor's ratings and a cutoff value of 10.5 for the Performance Fitness Rating Scale (R(2) = 0.918, F[41] = 3.794, p = 0.003). Classification And Regression Tree was also plotted to identify the profile of cases, with an overall accuracy of 0.861 (relative error, 0.26). Use of both inference statistics and data mining techniques enables the decision tree of neurocognitive assessments to be more readily applied by therapists in vocational rehabilitation, and thus directly improve the efficiency and efficacy of the process.

Selecting a Business Major within the College of Business

ERIC Educational Resources Information Center

Roach, David W.; McGaughey, Ronald E.; Downey, James P.

2012-01-01

This study employed a survey in examining the important influences that shape a student's selection of a major in the College of Business (COB). In particular, it compared these influences, by major, to assess which items were most (and least) important to the students majoring in accounting, general business, finance, management, marketing, and…

Validity and Reliability of Enzyme Immunoassays Using Leishmania major or L. infantum Antigens for the Diagnosis of Canine Visceral Leishmaniasis in Brazil

PubMed Central

de Arruda, Mauro Maciel; Figueiredo, Fabiano Borges; Cardoso, Fernanda Alvarenga; Hiamamoto, Roberto Mitsuyoshi; Brazuna, Júlia Cristina Macksoud; de Oliveira, Maria Regina Fernandes; Noronha, Elza Ferreira; Romero, Gustavo Adolfo Sierra

2013-01-01

Background American visceral leishmaniasis is caused by the protozoan Leishmania infantum. Dogs are the main reservoirs in the domestic transmission cycle. The limited accuracy of diagnostic tests for canine leishmaniasis may contribute to the lack of impact of control measures recommended by the Brazilian Ministry of Health. The objective of this study was to estimate the accuracy of two enzyme-linked immunosorbent assays employing L. major or L. infantum antigens and their reliability between three laboratories of different levels of complexity. Methods A validation study of ELISA techniques using L. major or L. infantum antigens was conducted. Direct visualization of the parasite in hematoxylin/eosin-stained histopathological sections, immunohistochemistry, and isolation of the parasite in culture.were used as gold standard. An animal that was positive in at least one of the tests was defined as infected with L. infantum. Serum samples collected from 1,425 dogs were analyzed. Samples were separated in three aliquots and tested in three different laboratories. Sensitivity, specificity and the area under de ROC curve were calculated and the reliability was evaluated between the participant laboratories. Results The sensitivity was 91.8% and 89.8% for the L. major and L. infantum assays, respectively. The specificity was 83.75% and 82.7% for the L. major and L. infantum assays, respectively. The area under de ROC curve was 0.920 and 0.898 for L. major and L. infantum, respectively. The mean intraclass correlation coefficients between laboratories ranged from 0.890 to 0.948 when L. major was used as antigen, and from 0.818 to 0.879 when L. infantum was used. Interpretation ELISA tests using L. major or L. infantum antigens have similar accuracy and reliability. Our results do not support the substitution of the L. major antigen of the ELISA test currently used for the diagnosis of canine visceral leishmaniasis in Brazil. PMID:23922884

Directly manipulated free-form deformation image registration.

PubMed

Tustison, Nicholas J; Avants, Brian B; Gee, James C

2009-03-01

Previous contributions to both the research and open source software communities detailed a generalization of a fast scalar field fitting technique for cubic B-splines based on the work originally proposed by Lee . One advantage of our proposed generalized B-spline fitting approach is its immediate application to a class of nonrigid registration techniques frequently employed in medical image analysis. Specifically, these registration techniques fall under the rubric of free-form deformation (FFD) approaches in which the object to be registered is embedded within a B-spline object. The deformation of the B-spline object describes the transformation of the image registration solution. Representative of this class of techniques, and often cited within the relevant community, is the formulation of Rueckert who employed cubic splines with normalized mutual information to study breast deformation. Similar techniques from various groups provided incremental novelty in the form of disparate explicit regularization terms, as well as the employment of various image metrics and tailored optimization methods. For several algorithms, the underlying gradient-based optimization retained the essential characteristics of Rueckert's original contribution. The contribution which we provide in this paper is two-fold: 1) the observation that the generic FFD framework is intrinsically susceptible to problematic energy topographies and 2) that the standard gradient used in FFD image registration can be modified to a well-understood preconditioned form which substantially improves performance. This is demonstrated with theoretical discussion and comparative evaluation experimentation.

Design and Optimisation of Electrostatic Precipitator for Diesel Exhaust

NASA Astrophysics Data System (ADS)

Srinivaas, A.; Sathian, Samanyu; Ramesh, Arjun

2018-02-01

The principle of an industrially used emission reduction technique is employed in automotive diesel exhaust to reduce the diesel particulate emission. As the Emission regulation are becoming more stringent legislations have been formulated, due to the hazardous increase in the air quality index in major cities. Initially electrostatic precipitation principle and working was investigated. The High voltage requirement in an Electrostatic precipitator is obtained by designing an appropriate circuit in MATLAB -SIMULINK. Mechanical structural design of the new model after treatment device for the specific diesel exhaust was done. Fluid flow analysis of the ESP model was carried out using ANSYS CFX for optimized fluid with a reduced back pressure. Design reconsideration was done in accordance with fluid flow analysis. Accordingly, a new design is developed by considering diesel particulate filter and catalytic converter design to ESP model.

Slow Scan Telemedicine

NASA Technical Reports Server (NTRS)

1984-01-01

Originally developed under contract for NASA by Ball Bros. Research Corporation for acquiring visual information from lunar and planetary spacecraft, system uses standard closed circuit camera connected to a device called a scan converter, which slows the stream of images to match an audio circuit, such as a telephone line. Transmitted to its destination, the image is reconverted by another scan converter and displayed on a monitor. In addition to assist scans, technique allows transmission of x-rays, nuclear scans, ultrasonic imagery, thermograms, electrocardiograms or live views of patient. Also allows conferencing and consultation among medical centers, general practitioners, specialists and disease control centers. Commercialized by Colorado Video, Inc., major employment is in business and industry for teleconferencing, cable TV news, transmission of scientific/engineering data, security, information retrieval, insurance claim adjustment, instructional programs, and remote viewing of advertising layouts, real estate, construction sites or products.

Protocols for Biotechnological Interventions in Improvement of Vanilla (Vanilla planifolia Andrews.).

PubMed

Divakaran, Minoo; Babu, K Nirmal; Peter, K V

2016-01-01

Vanilla (Vanilla planifolia Andrews (syn. V. fragrans Salisb.), a native of Central America, is the primary source of natural vanillin and plays a major role in the global economy. The gene pool of vanilla is threatened by deforestation and overcollection that has resulted in disappearance of natural habitats and wild species. Continuous vegetative propagation and lack of natural seed set and sufficient variations in the gene pool hamper crop improvement programs. In vitro techniques, one of the key tools of plant biotechnology, can be employed for overcoming specific problems, viz. production of disease-free clones, inducing somaclonal variations, developing hybrids, gene pool conservation, incorporating desired traits by distant hybridization, genetic engineering, etc. However, realization of these objectives necessitates standardization of protocols. This chapter describes the various protocols optimized for crop improvement in Vanilla species.

NASA scheduling technologies

NASA Technical Reports Server (NTRS)

Adair, Jerry R.

1994-01-01

This paper is a consolidated report on ten major planning and scheduling systems that have been developed by the National Aeronautics and Space Administration (NASA). A description of each system, its components, and how it could be potentially used in private industry is provided in this paper. The planning and scheduling technology represented by the systems ranges from activity based scheduling employing artificial intelligence (AI) techniques to constraint based, iterative repair scheduling. The space related application domains in which the systems have been deployed vary from Space Shuttle monitoring during launch countdown to long term Hubble Space Telescope (HST) scheduling. This paper also describes any correlation that may exist between the work done on different planning and scheduling systems. Finally, this paper documents the lessons learned from the work and research performed in planning and scheduling technology and describes the areas where future work will be conducted.

Biomedical studies by PIXE

NASA Astrophysics Data System (ADS)

Afarideh, H.; Amirabadi, A.; Hadji-Saeid, S. M.; Mansourian, N.; Kaviani, K.; Zibafar, E.

1996-04-01

In the present biomedical research, PIXE a powerful technique for elemental analysis was employed to illustrate the importance of multi-elemental determination of serum trace elements in two cases of great medical interest. Those are evaluation of the desferroxamine drug (DPO), a widely used therapy for patient with β-thalassemia-Major (β-thal-M), and investigation of elemental variations in blood-serum in hyperbilirubinamia new-borns before and after blood transfusion (BT). The purpose of the work is to demonstrate the various aspects of PIXE analysis by some practical examples as well as to draw some general conclusions regarding the cure of those patients with the above mentioned disorders or diseases. To present in details each case, we divide the paper in two parts: part 1 and part 2 to consider the experimental procedure as well as the results individually.

Spectral fingerprinting of polycyclic aromatic hydrocarbons in high-volume ambient air samples by constant energy synchronous luminescence spectroscopy

USGS Publications Warehouse

Kerkhoff, M.J.; Lee, T.M.; Allen, E.R.; Lundgren, D.A.; Winefordner, J.D.

1985-01-01

A high-volume sampler fitted with a glass-fiber filter and backed by polyurethane foam (PUF) was employed to collect airborne particulate and gas-phase polycylic aromatic hydrocarbons (PAHs) in ambient air. Samples were collected from four sources representing a range of environmental conditions: gasoline engine exhaust, diesel engine exhaust, air near a heavily traveled interstate site, and air from a moderately polluted urban site. Spectral fingerprints of the unseparated particulate and gas-phase samples were obtained by constant energy synchronous luminescence spectroscopy (CESLS). Five major PAHs in the gas-phase extracts were characterized and estimated. The compatibility of a high-volume sampling method using polyurethane foam coupled with CESLS detection is explored for use as a screening technique for PAHs in ambient air. ?? 1985 American Chemical Society.

Walking and talking the tree of life: Why and how to teach about biodiversity.

PubMed

Ballen, Cissy J; Greene, Harry W

2017-03-01

Taxonomic details of diversity are an essential scaffolding for biology education, yet outdated methods for teaching the tree of life (TOL), as implied by textbook content and usage, are still commonly employed. Here, we show that the traditional approach only vaguely represents evolutionary relationships, fails to denote major events in the history of life, and relies heavily on memorizing near-meaningless taxonomic ranks. Conversely, a clade-based strategy-focused on common ancestry, monophyletic groups, and derived functional traits-is explicitly based on Darwin's "descent with modification," provides students with a rational system for organizing the details of biodiversity, and readily lends itself to active learning techniques. We advocate for a phylogenetic classification that mirrors the TOL, a pedagogical format of increasingly complex but always hierarchical presentations, and the adoption of active learning technologies and tactics.

Technical Progress: Three Ways to Keep Up.

ERIC Educational Resources Information Center

Patterson, J. Wayne; And Others

1988-01-01

The authors analyzed three techniques employed in technological forecasting: (1) brainstorming, (2) extrapolation, and (3) scenario writing. They argue that these techniques have value to practitioners, particularly managers, who are often affected by technological change. (CH)

Using a Nonaversive Procedure to Decrease Refusals.

ERIC Educational Resources Information Center

Spooner, Fred; And Others

1990-01-01

A nonaversive technique was used to teach a severely handicapped woman to decrease her refusals. The technique employed precision teaching via precise daily measurement strategies, environmental analysis, and a focus on building appropriate behavior. (JDD)

Comparison of univariate and multivariate models for prediction of major and minor elements from laser-induced breakdown spectra with and without masking

NASA Astrophysics Data System (ADS)

Dyar, M. Darby; Fassett, Caleb I.; Giguere, Stephen; Lepore, Kate; Byrne, Sarah; Boucher, Thomas; Carey, CJ; Mahadevan, Sridhar

2016-09-01

This study uses 1356 spectra from 452 geologically-diverse samples, the largest suite of LIBS rock spectra ever assembled, to compare the accuracy of elemental predictions in models that use only spectral regions thought to contain peaks arising from the element of interest versus those that use information in the entire spectrum. Results show that for the elements Si, Al, Ti, Fe, Mg, Ca, Na, K, Ni, Mn, Cr, Co, and Zn, univariate predictions based on single emission lines are by far the least accurate, no matter how carefully the region of channels/wavelengths is chosen and despite the prominence of the selected emission lines. An automated iterative algorithm was developed to sweep through all 5485 channels of data and select the single region that produces the optimal prediction accuracy for each element using univariate analysis. For the eight major elements, use of this technique results in a 35% improvement in prediction accuracy; for minors, the improvement is 13%. The best wavelength region choice for any given univariate analysis is likely to be an inherent property of the specific training set that cannot be generalized. In comparison, multivariate analysis using partial least-squares (PLS) almost universally outperforms univariate analysis. PLS using all the same wavelength regions from the univariate analysis produces results that improve in accuracy by 63% for major elements and 3% for minor element. This difference is likely a reflection of signal to noise ratios, which are far better for major elements than for minor elements, and likely limit their prediction accuracy by any technique. We also compare predictions using specific wavelength ranges for each element against those employing all channels. Masking out channels to focus on emission lines from a specific element that occurs decreases prediction accuracy for major elements but is useful for minor elements with low signals and proportionally much higher noise; use of PLS rather than univariate analysis is still recommended. Finally, we tested the generalizability of our results by analyzing a second data set from a different instrument. Overall prediction accuracies for the mixed data sets are higher than for either set alone for all major and minor elements except Ni, Cr, and Co, where results are roughly comparable.

APPROACHES TO USE IN ASSESSING NEEDS FOR, CONTENT OF, AND CERTAIN FACTORS TO BE CONSIDERED IN OFFERING HOME ECONOMICS COURSES PREPARING FOR GAINFUL EMPLOYMENT.

ERIC Educational Resources Information Center

COZINE, JUNE

EDUCATIONAL GUIDELINES AND TECHNIQUES WERE DEVELOPED AND NEEDS ESTABLISHED FOR PLANNING GAINFUL EMPLOYMENT PROGRAMS IN THE FIELD OF HOME ECONOMICS, PARTICULARLY IN THE AREAS OF CHILD CARE AND CLOTHING SERVICES. TWO SEPARATE SURVEYS WERE CONDUCTED. THE FIRST INVOLVED CONTACTS WITH POTENTIAL EMPLOYERS AND OTHER INDIVIDUALS WHO HAD KNOWLEDGE OF THE…

The contemporary role of 1 vs. 2-stage repair for proximal hypospadias.

PubMed

Dason, Shawn; Wong, Nathan; Braga, Luis H

2014-12-01

This review discusses the most commonly employed techniques in the repair of proximal hypospadias, highlighting the advantages and disadvantages of single versus staged surgical techniques. Hypospadias can have a spectrum of severity with a urethral meatus ranging from the perineum to the glans. Associated abnormalities are commonly found with proximal hypospadias and encompass a large spectrum, including ventral curvature (VC) up to 50 degrees or more, ventral skin deficiency, a flattened glans, penile torsion and penoscrotal transposition. Our contemporary understanding of hypospadiology is comprised of a foundation built by experts who have described a number of techniques and their outcomes, combined with survey data detailing practice patterns. The two largest components of hypospadias repair include repair of VC and urethroplasty. VC greater than 20 degrees is considered clinically relevant to warrant surgical correction. To repair VC, the penis is first degloved-a procedure that may reduce or remove curvature by itself in some cases. Residual curvature is then repaired with dorsal plication techniques, transection of the urethral plate, and/or ventral lengthening techniques. Urethroplasty takes the form of 1- or 2-stage repairs. One-stage options include the tubularized incised urethroplasty (TIP) or various graft or flap-based techniques. Two-stage options also include grafts or flaps, including oral mucosal and preputial skin grafting. One stage repairs are an attractive option in that they may reduce cost, hospital stay, anesthetic risks, and time to the final result. The downside is that these repairs require mastery of multiple techniques may be more complex, and-depending on technique-have higher complication rates. Two-stage repairs are preferred by the majority of surveyed hypospadiologists. The 2-stage repair is versatile and has satisfactory outcomes, but necessitates a second procedure. Given the lack of clear high-quality evidence supporting the superiority of one approach over the others, hypospadiologists should develop their own algorithm, which gives them the best outcomes.

MEMS scanning micromirror for optical coherence tomography.

PubMed

Strathman, Matthew; Liu, Yunbo; Keeler, Ethan G; Song, Mingli; Baran, Utku; Xi, Jiefeng; Sun, Ming-Ting; Wang, Ruikang; Li, Xingde; Lin, Lih Y

2015-01-01

This paper describes an endoscopic-inspired imaging system employing a micro-electromechanical system (MEMS) micromirror scanner to achieve beam scanning for optical coherence tomography (OCT) imaging. Miniaturization of a scanning mirror using MEMS technology can allow a fully functional imaging probe to be contained in a package sufficiently small for utilization in a working channel of a standard gastroesophageal endoscope. This work employs advanced image processing techniques to enhance the images acquired using the MEMS scanner to correct non-idealities in mirror performance. The experimental results demonstrate the effectiveness of the proposed technique.

MEMS scanning micromirror for optical coherence tomography

PubMed Central

Strathman, Matthew; Liu, Yunbo; Keeler, Ethan G.; Song, Mingli; Baran, Utku; Xi, Jiefeng; Sun, Ming-Ting; Wang, Ruikang; Li, Xingde; Lin, Lih Y.

2014-01-01

This paper describes an endoscopic-inspired imaging system employing a micro-electromechanical system (MEMS) micromirror scanner to achieve beam scanning for optical coherence tomography (OCT) imaging. Miniaturization of a scanning mirror using MEMS technology can allow a fully functional imaging probe to be contained in a package sufficiently small for utilization in a working channel of a standard gastroesophageal endoscope. This work employs advanced image processing techniques to enhance the images acquired using the MEMS scanner to correct non-idealities in mirror performance. The experimental results demonstrate the effectiveness of the proposed technique. PMID:25657887

Multidisciplinary aeroelastic analysis of a generic hypersonic vehicle

NASA Technical Reports Server (NTRS)

Gupta, K. K.; Petersen, K. L.

1993-01-01

This paper presents details of a flutter and stability analysis of aerospace structures such as hypersonic vehicles. Both structural and aerodynamic domains are discretized by the common finite element technique. A vibration analysis is first performed by the STARS code employing a block Lanczos solution scheme. This is followed by the generation of a linear aerodynamic grid for subsequent linear flutter analysis within subsonic and supersonic regimes of the flight envelope; the doublet lattice and constant pressure techniques are employed to generate the unsteady aerodynamic forces. Flutter analysis is then performed for several representative flight points. The nonlinear flutter solution is effected by first implementing a CFD solution of the entire vehicle. Thus, a 3-D unstructured grid for the entire flow domain is generated by a moving front technique. A finite element Euler solution is then implemented employing a quasi-implicit as well as an explicit solution scheme. A novel multidisciplinary analysis is next effected that employs modal and aerodynamic data to yield aerodynamic damping characteristics. Such analyses are performed for a number of flight points to yield a large set of pertinent data that define flight flutter characteristics of the vehicle. This paper outlines the finite-element-based integrated analysis procedures in detail, which is followed by the results of numerical analyses of flight flutter simulation.

Tuning of PID controller using optimization techniques for a MIMO process

NASA Astrophysics Data System (ADS)

Thulasi dharan, S.; Kavyarasan, K.; Bagyaveereswaran, V.

2017-11-01

In this paper, two processes were considered one is Quadruple tank process and the other is CSTR (Continuous Stirred Tank Reactor) process. These are majorly used in many industrial applications for various domains, especially, CSTR in chemical plants.At first mathematical model of both the process is to be done followed by linearization of the system due to MIMO process and controllers are the major part to control the whole process to our desired point as per the applications so the tuning of the controller plays a major role among the whole process. For tuning of parameters we use two optimizations techniques like Particle Swarm Optimization, Genetic Algorithm. The above techniques are majorly used in different applications to obtain which gives the best among all, we use these techniques to obtain the best tuned values among many. Finally, we will compare the performance of the each process with both the techniques.

In-situ identification of anti-personnel mines using acoustic resonant spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Perry, R L; Roberts, R S

1999-02-01

A new technique for identifying buried Anti-Personnel Mines is described, and a set of preliminary experiments designed to assess the feasibility of this technique is presented. Analysis of the experimental results indicates that the technique has potential, but additional work is required to bring the technique to fruition. In addition to the experimental results presented here, a technique used to characterize the sensor employed in the experiments is detailed.

Intraseptal anesthesia: a review of a relevant injection technique.

PubMed

Woodmansey, Karl

2005-01-01

Although overshadowed by intraosseous anesthesia and the periodontal ligament injection, intraseptal anesthesia remains a useful local anesthesia technique for general dentists. Intraseptal anesthesia can be employed with safety and efficacy as an alternative to conventional local infiltration or regional nerve block injections. It also can serve as an adjunctive technique when conventional techniques fail to achieve adequate local anesthesia. This article reviews the intraseptal anesthesia technique, including its indications and limitations.

Effectiveness of metaphoric facilitation techniques in a challenge course program on the empowerment of women participants

Treesearch

Penny A. James; Lynn Anderson; Anderson Young

2007-01-01

Research has shown support for the efficacy of differing processing techniques, particularly isomorphic framing. Feminist practitioners contend this methodology disempowers participants. Proponents argue this could result only from improper implementation. This experiment employed a facilitation technique (control, derived, isomorphic) between subjects design with time...

Impacts of Vocabulary Acquisition Techniques Instruction on Students' Learning

ERIC Educational Resources Information Center

Orawiwatnakul, Wiwat

2011-01-01

The objectives of this study were to determine how the selected vocabulary acquisition techniques affected the vocabulary ability of 35 students who took EN 111 and investigate their attitudes towards the techniques instruction. The research study was one-group pretest and post-test design. The instruments employed were in-class exercises…

Incorporating Nonparametric Statistics into Delphi Studies in Library and Information Science

ERIC Educational Resources Information Center

Ju, Boryung; Jin, Tao

2013-01-01

Introduction: The Delphi technique is widely used in library and information science research. However, many researchers in the field fail to employ standard statistical tests when using this technique. This makes the technique vulnerable to criticisms of its reliability and validity. The general goal of this article is to explore how…

Exploring Fencerows--An Outdoor Teaching Technique.

ERIC Educational Resources Information Center

Rillo, Thomas J.

The exploration of fencerows as an outdoor teaching technique is described. The concepts that can be developed as students walk down the fencerows are related to science, life styles, and economy. By dividing a class into small groups, a teacher can employ problem-solving techniques in fencerow exploration. The following group topics are possible…

Multibeam satellite EIRP adaptability for aeronautical communications.

NASA Technical Reports Server (NTRS)

Kinal, G. V.; Bisaga, J. J.

1973-01-01

EIRP enhancement and management techniques, emphasizing aeronautical communications and adaptable multibeam concepts, are classified and characterized. User requirement and demand characteristics that exploit the improvement available from each technique are identified, and the relative performance improvement of each is discussed. It is concluded that aeronautical satellite communications could benefit greatly by the employment of these techniques.

A Simulation of AI Programming Techniques in BASIC.

ERIC Educational Resources Information Center

Mandell, Alan

1986-01-01

Explains the functions of and the techniques employed in expert systems. Offers the program "The Periodic Table Expert," as a model for using artificial intelligence techniques in BASIC. Includes the program listing and directions for its use on: Tandy 1000, 1200, and 2000; IBM PC; PC Jr; TRS-80; and Apple computers. (ML)

The Role of the United States Employment Service in a Changing Economy. Studies in Employment and Unemployment.

ERIC Educational Resources Information Center

Haber, William; Kruger, Daniel

This monograph examines the developments which have influenced the United States Employment Service during the 30 years of its history, since the Wagner-Peyser Act of 1933. The major social and economic developments, the enabling legislation, and the issues and problems regarding the proper role of that service are discussed. Some of the…

Brevard County: Labor Pool Resource Study, 1981-1985. A Manufacturing Needs Assessment Coordinated by the Brevard Economic Development Council.

ERIC Educational Resources Information Center

Brevard Community Coll., Cocoa, FL.

In fall 1981, 74 of Brevard County's major manufacturing firms and related industries were asked to provide detailed figures reflecting their 1982 employment, annual job vacancies, and projections for 1985 employment by job category, division, and title. Survey findings, based on responses from firms representing 75% of the employment within the…

It's Not Funny/It's Illegal. A Handbook of Laws Guaranteeing Equal Education and Employment Opportunities. Project SCOPE Book #3.

ERIC Educational Resources Information Center

Riley, Susan, Comp.; Keroack, Elizabeth, Comp.

This handbook contains summaries, discussions, and the texts of some of the major federal legislation that guarantees students protection from sex discrimination in the areas of education and employment. Explained first are the following employment laws: Title VII of the Civil Rights Act of 1962; Executive Order 11246, as amended by Executive…

Youth Employment, Psychosocial Health and the Importance of Person/Environment Fit: A Case Study of Two Scottish Rural Towns.

ERIC Educational Resources Information Center

Pavis, Stephen; Platt, Stephen; Hubbard, Gill

2002-01-01

Reports on the employment experiences of young people from two small rural Scottish towns. The majority of available employment was repetitive, and involved poor working conditions and limited opportunity for skill development or promotion. Most respondents recognized that in the longer term such work was detrimental to their quality of life and…

Hopes for the Future: Demographic and Personal Resources Associated with Self-Perceived Employability and Actual Employment among Senior Year Students

ERIC Educational Resources Information Center

Kasler, Jonathan; Zysberg, Leehu; Harel, Nofar

2017-01-01

Undergraduates approaching completion of their studies may embrace the prospect of entry into the world of work as a challenge or conversely, may view it with trepidation. This study explores three major personal resources that may be associated with how young undergraduates view their future employability: perceived hope, grit and emotional…

Sexual Inequality in the Workplace: An Employer-Specific Analysis of Pay Differences. Discussion Paper No. 502-78.

ERIC Educational Resources Information Center

Halaby, Charles N.

Sexual inequality is rooted in systematic male-female differences in employer-employee exchanges of productive resources for employment and pay. In an analysis of the effects of the differential distribution of personnel across the major job classes and hierarchical levels of a large utilities firm, the degree to which the male-female salary gap…

Employment, Employability and Higher Education in India: The Missing Links

ERIC Educational Resources Information Center

Khare, Mona

2014-01-01

The demand for labour in India is likely to remain high and robust in the coming years, both nationally and internationally. But this would demand skilled and qualified labour. The employability of Indian youth has emerged as a major concern in recent years. Ironically, it is not just the uneducated and untrained that lack skills but it is also…

As UK Policy Strives to Make Access to Higher Education Easier for All, Is Discrimination in Employment Practice Still Apparent?

ERIC Educational Resources Information Center

Browne, Liz

2010-01-01

Reporting on research into two major employers recruiting to the financial services industry, this article draws on data collected from interns, recruitment professionals and graduate employees in their first year of employment. It poses a number of strategy- and outcome-related questions in an attempt to determine whether recruitment advisers are…

Transitions to Employment: Proceedings of the 1990 International Symposium on the Employment of Persons with Disabilities (Washington, D.C., June 3-5, 1990).

ERIC Educational Resources Information Center

McLaughlin, Margaret J., Ed.; And Others

This document presents the proceedings of a symposium which discussed critical issues in employment of persons with disabilities in Europe, Australia, and North America. After introductions, the major presentations included the following: "Labor Market Forces" (Roderick A. DeArment, U.S. Department of Labor); "Civil Rights in the…

Health care consumer reports: an evaluation of employer perspectives.

PubMed

Longo, Daniel R

2004-01-01

The proliferation of health care consumer reports (also known as "consumer guides," "report cards," and "performance reports") designed to assist consumers in making more informed health care decisions makes it vital to understand the perspective of employers who provide the vast majority of health insurance to the working population regarding the use of these reports. There is little empirical evidence on how consumer reports are used by employers to make health care purchasing decisions. This study fills that gap by surveying 154 businesses in Boone County, Missouri, regarding their evaluation of a consumer guide. The majority of employers surveyed indicate that the report will not have a direct effect on their health care purchasing decisions. However, they indicate that the reports are "positive and worthwhile" and their responses reflect a favorable view of the health care organization that developed and disseminated the report. Additionally, findings indicate that employers generally prefer consumer reports as a means to compare local health care institutions, rather than reviewing national averages to locate the same information. Report developers should take precautions to determine the intent of such reports, as they may not achieve the objective of changing employers' health care purchasing behavior.

(Handicap opportunities and programs in employment). Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moon, J.P.C.

1980-01-01

Passive solar windowbox heaters were constructed by handicapped individuals and displayed in Vermont public buildings. The training enables the majority of the participants to qualify for other employment using skills developed during planning and constructing the devices. (PSB)

Advanced Methodology for Simulation of Complex Flows Using Structured Grid Systems

NASA Technical Reports Server (NTRS)

Steinthorsson, Erlendur; Modiano, David

1995-01-01

Detailed simulations of viscous flows in complicated geometries pose a significant challenge to current capabilities of Computational Fluid Dynamics (CFD). To enable routine application of CFD to this class of problems, advanced methodologies are required that employ (a) automated grid generation, (b) adaptivity, (c) accurate discretizations and efficient solvers, and (d) advanced software techniques. Each of these ingredients contributes to increased accuracy, efficiency (in terms of human effort and computer time), and/or reliability of CFD software. In the long run, methodologies employing structured grid systems will remain a viable choice for routine simulation of flows in complex geometries only if genuinely automatic grid generation techniques for structured grids can be developed and if adaptivity is employed more routinely. More research in both these areas is urgently needed.

Ultrasonic technique for inspection of GPHS capsule girth weld integrity

NASA Astrophysics Data System (ADS)

Placr, Arnost

1993-05-01

An innovative nondestructive examination (NDE) technique for the inspection of integrity of General Purpose Heat Source (GPHS) capsule girth welds was developed employing a Lamb wave as the mode of the sound propagation. Reliability of the Lamb wave technique was tested on GPHS capsules using plutonium pallet simulators. All ten capsules, which were previously rejected, passed ultrasonic (UT) inspection using the Lamb wave technique.

Myocardial blood flow: Roentgen videodensitometry techniques

NASA Technical Reports Server (NTRS)

Smith, H. C.; Robb, R. A.; Wood, E. H.

1975-01-01

The current status of roentgen videodensitometric techniques that provide an objective assessment of blood flow at selected sites within the coronary circulation were described. Roentgen videodensitometry employs conventional radiopaque indicators, radiological equipment and coronary angiographic techniques. Roentgen videodensitometry techniques developed in the laboratory during the past nine years, and for the past three years were applied to analysis of angiograms in the clinical cardiac catheterization laboratory.

Silver-based Antibacterial Surfaces for Drinking Water Disinfection - An overview

EPA Science Inventory

Risks associated with current disinfection techniques, including the formation of disinfection by-products and multi-drug resistant bacterial species, have prompted the exploration of advanced disinfection methods. One such technique employs silver nanoparticles incorporation on ...

Development of an Electron-capture Technique Specific for Explosives Detection

DOT National Transportation Integrated Search

1974-07-01

This document contains information on the design, fabrication, and testing of a prototype detector specific for explosives which employs electron-capture sensors. The technique used exploits the observation that the electronegative vapors from explos...

Simulation of wind turbine wakes using the actuator line technique

PubMed Central

Sørensen, Jens N.; Mikkelsen, Robert F.; Henningson, Dan S.; Ivanell, Stefan; Sarmast, Sasan; Andersen, Søren J.

2015-01-01

The actuator line technique was introduced as a numerical tool to be employed in combination with large eddy simulations to enable the study of wakes and wake interaction in wind farms. The technique is today largely used for studying basic features of wakes as well as for making performance predictions of wind farms. In this paper, we give a short introduction to the wake problem and the actuator line methodology and present a study in which the technique is employed to determine the near-wake properties of wind turbines. The presented results include a comparison of experimental results of the wake characteristics of the flow around a three-bladed model wind turbine, the development of a simple analytical formula for determining the near-wake length behind a wind turbine and a detailed investigation of wake structures based on proper orthogonal decomposition analysis of numerically generated snapshots of the wake. PMID:25583862

Distinguishing the Factors Influencing College Students' Choice of Major

ERIC Educational Resources Information Center

Beggs, Jeri Mullins; Bantham, John H.; Taylor, Steven

2008-01-01

Choosing a college major represents a major life decision--a decision that research has shown to be the most frequently identified life regret for Americans. The focus of this study is to identify the foundations of the psychological process by which undergraduate students select their academic majors. A means-end analysis was first employed to…

Report from Massachusetts: employers largely support health care reform, and few signs of crowd-out appear.

PubMed

Gabel, Jon R; Whitmore, Heidi; Pickreign, Jeremy

2008-01-01

Based on a 2007 survey of 1,056 randomly selected Massachusetts firms, this paper presents findings about employers' attitudes about, knowledge of, and responses to recently enacted reform legislation. A majority of Massachusetts employers agree that all employers bear some responsibility for providing health benefits, firms not offering benefits should be required to pay a "fair share" contribution up to $295 annually per employee, and employers with ten or fewer employees should not be exempt from this requirement. Only 24 percent of employers with 3-50 workers are familiar with the Connector purchasing pool. About 3 percent of Massachusetts small employers intend to drop coverage, similar to national figures.

Repair of Double Head Pectoralis Major Tendon Avulsion into its Native Footprint Using Bi-cortical EndoButtons and Tendon Sliding Technique.

PubMed

Prabhu, Jagadish; Faqi, Mohammed Khalid; Alkhalifa, Fahad; Tayara, Bader Kamal; Awad, Rashad Khamis

2017-01-01

Injuries to the pectoralis major muscle are relatively infrequent. The mechanism of injury is usually an eccentric shortening of the pectoralis major under heavy load, such as when performing a bench press exercise. We report a case that presented to us with a history of sudden pain in the left pectoral region while doing heavy bench press exercise. The patient sustained a type III D pectoralis muscle -tendon avulsion. Surgical repair was done through a bi-cortical tendon sliding technique using two cortical buttons. In this article we describe our modifications to the previously described surgical technique for the pectoralis major tendon repair using the EndoButton and tension - slide technique, aiming to overcome the possible complications.

Towards efficient backward-in-time adjoint computations using data compression techniques

DOE PAGES

Cyr, E. C.; Shadid, J. N.; Wildey, T.

2014-12-16

In the context of a posteriori error estimation for nonlinear time-dependent partial differential equations, the state-of-the-practice is to use adjoint approaches which require the solution of a backward-in-time problem defined by a linearization of the forward problem. One of the major obstacles in the practical application of these approaches, we found, is the need to store, or recompute, the forward solution to define the adjoint problem and to evaluate the error representation. Our study considers the use of data compression techniques to approximate forward solutions employed in the backward-in-time integration. The development derives an error representation that accounts for themore » difference between the standard-approach and the compressed approximation of the forward solution. This representation is algorithmically similar to the standard representation and only requires the computation of the quantity of interest for the forward solution and the data-compressed reconstructed solution (i.e. scalar quantities that can be evaluated as the forward problem is integrated). This approach is then compared with existing techniques, such as checkpointing and time-averaged adjoints. Lastly, we provide numerical results indicating the potential efficiency of our approach on a transient diffusion–reaction equation and on the Navier–Stokes equations. These results demonstrate memory compression ratios up to 450×450× while maintaining reasonable accuracy in the error-estimates.« less

Using "Rebar" to Stabilize Rigid Chest Wall Reconstruction.

PubMed

Robinson, Lary A; Grubbs, Deanna M

2016-04-01

After major chest wall resection, reconstruction of the bony defect with a rigid prosthesis is mandatory to protect the underlying thoracic organs, and to prevent flail chest physiology. Although many methods have been described for chest wall reconstruction, a commonly used technique employs a composite Marlex (polypropylene) mesh with methyl-methacrylate cement sandwiched between two layers of mesh (MMS), which is tailored to the defect size and shape. In building construction, steel "rebar" is used to strengthen and reinforce masonry structures. To avoid the initial residual motion of the rigid prosthesis used to reconstruct very large defects, particularly the sternum, we devised a simple technique of adding one or more Steinmann steel pins as "rebar" to strengthen and immediately stabilize the prosthesis to the surrounding ribs and sternum. For the very large defects, particularly over the heart and great vessels, titanium mesh may also be readily added into the sandwich construction for increased strength and to prevent late prosthetic fractures. Short- and long-term results of this inexpensive modification of the MMS reconstruction technique are excellent. This modified MMS tailor-made prosthesis is only one-third the cost of the recently popular prosthetic titanium systems, takes much less operative time to create and implant, and avoids the well-described complications of late titanium bar fracture and erosion/infection as well as loosening of screws and/or titanium bars. Georg Thieme Verlag KG Stuttgart · New York.

Quantitative detection of astaxanthin and cantaxanthin in Atlantic salmon by resonance Raman spectroscopy

NASA Astrophysics Data System (ADS)

Ermakov, Igor V.; Ermakova, Maia R.; Gellermann, Werner

2006-02-01

Two major carotenoids species found in salmonids muscle tissues are astaxanthin and cantaxanthin. They are taken up from fish food and are responsible for the attractive red-orange color of salmon filet. Since carotenoids are powerful antioxidants and biomarkers of nutrient consumption, they are thought to indicate fish health and resistance to diseases in fish farm environments. Therefore, a rapid, accurate, quantitative optical technique for measuring carotenoid content in salmon tissues is of economic interest. We demonstrate the possibility of using fast, selective, quantitative detection of astaxanthin and cantaxanthin in salmon muscle tissues, employing resonance Raman spectroscopy. Analyzing strong Raman signals originating from the carbon-carbon double bond stretch vibrations of the carotenoid molecules under blue laser excitation, we are able to characterize quantitatively the concentrations of carotenoids in salmon muscle tissue. To validate the technique, we compared Raman data with absorption measurements of carotenoid extracts in acetone. A close correspondence was observed in absorption spectra for tissue extract in acetone and a pure astaxanthin solution. Raman results show a linear dependence between Raman and absorption data. The proposed technique holds promise as a method of rapid screening of carotenoid levels in fish muscle tissues and may be attractive for the fish farm industry to assess the dietary status of salmon, risk for infective diseases, and product quality control.

Hyperthermia with implanted electrodes: in vitro and in vivo correlations.

PubMed

Lilly, M B; Brezovich, I A; Atkinson, W; Chakraborty, D; Durant, J R; Ingram, J; McElvein, R B

1983-03-01

Hyperthermia as a treatment for cancer has elicited much recent interest. However, major difficulties persist both in the technology for heating deep-seated tumors, and in thermal dosimetry. We have investigated a heating technique for deep-seated neoplasms that employs an internal implanted electrode and an external electrode to apply radiofrequency current to a tumor mass. The internal electrode consists of an array of stainless steel needles or wires which define a Faraday cage within the tumor, while the external electrode consists of a variety of electrical conductors at the skin surface. Phantom measurements have closely reproduced calculated temperature distributions. The temperature profiles within the volume enclosed by the internal electrode show relatively homogenous heating. Temperature measurements in a rat tumor model have demonstrated that significant heating within such an internal electrode array is easily obtained. The heating may extend some centimeters outside the electrode. Using a dog model we have shown that with such a treatment technique the temperature profiles obtained are reproducible both spatially and temporally. A case report of a clinical application is presented. A 5 cm bronchogenic carcinoma was easily heated without significant heating of the surrounding normal lung, and without apparent toxicity. Such a technique may be applicable to a variety of operable but unresectable neoplasms. The reproducibility and relative homogeneity of heating suggest possible usefulness in combined modality trials.