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Sample records for malykh doz ioniziruyushchej

  1. Passive seismic tomography application for cave monitoring in DOZ underground mine PT. Freeport Indonesia

    NASA Astrophysics Data System (ADS)

    Nurhandoko, Bagus Endar B.; Wely, Woen; Setiadi, Herlan; Riyanto, Erwin

    2015-04-01

    It is already known that tomography has a great impact for analyzing and mapping unknown objects based on inversion, travel time as well as waveform inversion. Therefore, tomography has used in wide area, not only in medical but also in petroleum as well as mining. Recently, tomography method is being applied in several mining industries. A case study of tomography imaging has been carried out in DOZ ( Deep Ore Zone ) block caving mine, Tembagapura, Papua. Many researchers are undergoing to investigate the properties of DOZ cave not only outside but also inside which is unknown. Tomography takes a part for determining this objective.The sources are natural from the seismic events that caused by mining induced seismicity and rocks deformation activity, therefore it is called as passive seismic. These microseismic travel time data are processed by Simultaneous Iterative Reconstruction Technique (SIRT). The result of the inversion can be used for DOZ cave monitoring. These information must be used for identifying weak zone inside the cave. In addition, these results of tomography can be used to determine DOZ and cave information to support mine activity in PT. Freeport Indonesia.

  2. Passive seismic tomography application for cave monitoring in DOZ underground mine PT. Freeport Indonesia

    SciTech Connect

    Nurhandoko, Bagus Endar B.; Wely, Woen; Setiadi, Herlan; Riyanto, Erwin

    2015-04-16

    It is already known that tomography has a great impact for analyzing and mapping unknown objects based on inversion, travel time as well as waveform inversion. Therefore, tomography has used in wide area, not only in medical but also in petroleum as well as mining. Recently, tomography method is being applied in several mining industries. A case study of tomography imaging has been carried out in DOZ ( Deep Ore Zone ) block caving mine, Tembagapura, Papua. Many researchers are undergoing to investigate the properties of DOZ cave not only outside but also inside which is unknown. Tomography takes a part for determining this objective.The sources are natural from the seismic events that caused by mining induced seismicity and rocks deformation activity, therefore it is called as passive seismic. These microseismic travel time data are processed by Simultaneous Iterative Reconstruction Technique (SIRT). The result of the inversion can be used for DOZ cave monitoring. These information must be used for identifying weak zone inside the cave. In addition, these results of tomography can be used to determine DOZ and cave information to support mine activity in PT. Freeport Indonesia.

  3. Rapid Semi-Quantitative Surface Mapping of Airborne-Dispersed Chemicals Using Mass Spectrometry

    EPA Science Inventory

    Chemicals can be dispersed accidentally, deliberately, or by weather-related events. Rapid mapping of contaminant distributions is necessary to assess exposure risks and to plan remediation, when needed. Ten pulverized aspirin or NoDozTM tablets containing caffeine wer...

  4. Problems following hippocampal irradiation in interventional radiologists - doses and potential effects: a Monte Carlo simulation.

    PubMed

    Chumak, V; Morgun, A; Bakhanova, E; Loganovsky, K; Loganovska, T; Marazziti, D

    2015-12-01

    Metoiu doslidzhennia bulo vyvchyty zakonomirnosti formuvannia doz na gipokamp v umovakh roboty likaria inter ventsiynogo kardiologa u rentgen operatsiyniy metodom Monte Karlo, a takozh vstanovyty Ikhniy zv’iazok z efek tyvnoiu dozoiu (shcho vykorystovuiet'sia u radiatsiynomu zakhysti) ta pokazanniamy indyvidual'nykh dozymetriv, shchob otsinyty ymovirnist' dosiagnennia protiagom kar’iery rivnia dozy, pry iakomu mozhut' sposterigatysia taki radiatsiyni efekty, iak kognityvni porushennia ta inshi nervovo psykhichni rozlady.Materialy i metody: modeliuvannia metodom Monte Karlo doz oprominennia gipokampiv likaria za dopomogoiu gibrydnogo voksel'no matematychnogo fantoma dlia typovykh angiografichnykh proektsiy ta energetychnykh spektriv, vlastyvykh dlia protsedur interventsiynoI kardiologiI.Rezul'taty: pokazano, shcho oprominennia golovy ie syl'no neodnoridnym i zalezhyt' vid rentgenografichnoI pro ektsiI: vidminnist' doz oprominennia livogo ta pravogo gipokampa mozhe stanovyty do dvokh z polovynoiu raziv, za pevnykh umov doza u livomu gipokampi mozhe vdvichi perevyshchuvaty efektyvnu dozu, iaku otsiniuvaly za poshyrenym algorytmom podviynoI dozymetriI.Vysnovky: dozy na gipokamp protiagom stazhu profesiynogo oprominennia mozhut' siagaty velychyn, pry iakykh mo zhut' z’iavytysia kognityvni ta emotsiyno povedinkovi porushennia, tomu glyboke vyvchennia efektiv oprominennia mozku pratsivnykiv interventsiynoI radiologiI ie vkray neobkhidnym.

  5. Reconstruction of national distribution of indoor radon concentration in Russia using results of regional indoor radon measurement programs.

    PubMed

    Yarmoshenko, I; Malinovsky, G; Vasilyev, A; Zhukovsky, M

    2015-12-01

    The aim of the paper is a reconstruction of the national distribution and estimation of the arithmetic average indoor radon concentration in Russia using the data of official annual 4-DOZ reports. Annual 4-DOZ reports summarize results of radiation measurements in 83 regions of Russian Federation. Information on more than 400,000 indoor radon measurements includes the average indoor radon isotopes equilibrium equivalent concentration (EEC) and number of measurements by regions and by three main types of houses: wooden, one-storey non-wooden, and multi-storey non-wooden houses. To reconstruct the national distribution, all-Russian model sample was generated by integration of sub-samples created using the results of each annual regional program of indoor radon measurements in each type of buildings. According to indoor radon concentration distribution reconstruction, all-Russian average indoor radon concentration is 48 Bq/m(3). Average indoor radon concentration by region ranges from 12 to 207 Bq/m(3). The 95-th percentile of the distribution is reached at indoor radon concentration 160 Bq/m(3). PMID:26313426

  6. Reconstruction of national distribution of indoor radon concentration in Russia using results of regional indoor radon measurement programs.

    PubMed

    Yarmoshenko, I; Malinovsky, G; Vasilyev, A; Zhukovsky, M

    2015-12-01

    The aim of the paper is a reconstruction of the national distribution and estimation of the arithmetic average indoor radon concentration in Russia using the data of official annual 4-DOZ reports. Annual 4-DOZ reports summarize results of radiation measurements in 83 regions of Russian Federation. Information on more than 400,000 indoor radon measurements includes the average indoor radon isotopes equilibrium equivalent concentration (EEC) and number of measurements by regions and by three main types of houses: wooden, one-storey non-wooden, and multi-storey non-wooden houses. To reconstruct the national distribution, all-Russian model sample was generated by integration of sub-samples created using the results of each annual regional program of indoor radon measurements in each type of buildings. According to indoor radon concentration distribution reconstruction, all-Russian average indoor radon concentration is 48 Bq/m(3). Average indoor radon concentration by region ranges from 12 to 207 Bq/m(3). The 95-th percentile of the distribution is reached at indoor radon concentration 160 Bq/m(3).

  7. Revealing the significance and polyphase tectonothermal evolution of a major metamorphic unit in an orogen: the central Sanandaj-Sirjan zone, Zagros Mts., Iran

    NASA Astrophysics Data System (ADS)

    Shakerardakani, Farzaneh; Neubauer, Franz; Genser, Johann; Liu, Xiaoming; Dong, Yunpeng; Monfaredi, Behzad; Benroider, Manfred; Finger, Fritz; Waitzinger, Michael

    2016-04-01

    The Dorud-Azna region in the central Sanandaj-Sirjan metamorphic belt plays a key role in promoting the tectonic evolution of Zagros orogen, within the frame of the Arabia-Eurasia collision zone. From footwall to hangingwall, structural data combined with the U-Pb zircon and extensive 40Ar-39Ar mineral dating survey demonstrate three metamorphosed tectonic units, which include: (1) The Triassic June complex is metamorphosed within greenschist facies conditions, overlain by (2) the amphibolite-grade metamorphic Galeh-Doz orthogneiss, which is intruded by mafic dykes, and (3) the Amphibolite-Metagabbro unit. To the east, these units were intruded by the Jurassic Darijune gabbro. We present U-Pb detrital zircon ages of a garnet-micaschist from the Amphibolite-Metagabbro unit, which yield six distinctive age groups, including a previously unrecognized Late Grenvillian age population at ~0.93 to 0.99 Ga. We speculate that this unique Late Grenvillian group coupled with biogeographic evidence suggests either relationship with the South China craton or to the "Gondwana superfan". The laser ablation ICP-MS U-Pb zircon ages of 608 ± 18 Ma and 588 ± 41 Ma of the granitic Galeh-Doz orthogneiss reveals a Panafrican basement same as known from the Yazd block of Central Iran. Geochemistry and Sr-Nd isotopes of alkaline and subalkaline mafic dykes within the Galeh-Doz orthogneiss show OIB-type to MORB-type and indicate involvement of both depleted and enriched sources for its genesis. The new 40Ar-39Ar amphibole age of ca. 322.2 ± 3.9 Ma from the alkaline mafic dyke implies Carboniferous cooling age after intrusion. The metagabbros (including the Dare-Hedavand metagabbro with a 206Pb/238U age of 314.6 ± 3.7 Ma) and amphibolites with E-MORB geochemical signature of the Amphibolite-Metagabbro unit represent an Upper Paleozoic rift. The geochemical composition of the Triassic greenschist facies metamorphosed June complex, implying formation in a same, but younger tectonic

  8. 10 rules for managing global innovation.

    PubMed

    Wilson, Keeley; Doz, Yves L

    2012-10-01

    More and more companies recognize that their dispersed, global operations are a treasure trove of ideas and capabilities for innovation. But it's proving harder than expected to unearth those ideas or exploit those capabilities. Part of the problem is that companies manage global innovation the same way they manage traditional, single-location projects. Single-location projects draw on a large reservoir of tacit knowledge, shared context, and trust that global projects lack. The management challenge, therefore, is to replicate the positive aspects of colocation while harnessing the opportunities of dispersion. In this article, Insead's Wilson and Doz draw on research into global strategy and innovation to present a set of guidelines for setting up and managing global innovation. They explore in detail the challenges that make global projects inherently different and show how these can be overcome by applying superior project management skills across teams, fostering a strong collaborative culture, and using a robust array of communications tools.

  9. Mineralogical discrimination of the pleistocene loess/paleosol sections in Srijem and Baranja, Croatia

    NASA Astrophysics Data System (ADS)

    Galović, Lidija; Peh, Zoran

    2016-06-01

    Previous investigations of the mineralogical composition of loess sections (loess, loess-like sediments, paleosols, alluvial intercalations) in the Carpathian Basin have concluded that the Danube River is the dominant control on the loessitic parent material. These investigations also identify a significant role for the Danube's tributaries in creating local variations. The north-south alignment of these sections forms a transect from the central part of the Carpathian Basin to its southern edge. In this work, the mineral origin of loess sediments was identified by using the multivariate statistical method of discriminant function analysis. Two models were constructed based on the modal composition as the suite of predictor (independent) variables: one is using geographic location as the a priori grouping criterion (SECTION); another employing the difference between the sampling media (LITHOLOGY). Both of the examined discriminant models demonstrate the existence of the mixing zones. The Erdut section is a clear mixture of the mineralogies at the other studied locations, while loesses appear generally intermediate in mineralogy between alluvium and paleosol. The main rationale for the observed difference in modal composition between the Šarengrad and other analyzed sections is the proximity of the Šarengrad section to the Sava River floodplain and Dinaric Ophiolite Zone (DOZ), both important source areas for aeolian sediments in the southern edge of the Carpathian Basin that transport material from the Central Bosnian Mountains unit of DOZ. Chemically, the most resistant heavy minerals together with opaque minerals are exclusively associated with paleosols, being typical products of geochemical pedogenic processes.

  10. Tectonic history of the central Sanandaj-Sirjan zone, Iran: Potentially Permian to Mesozoic polymetamorphism and implications for tectonics of the Sanandaj-Sirjan zone

    NASA Astrophysics Data System (ADS)

    Shakerardakani, Farzaneh; Neubauer, Franz; Genser, Johann; Masoudi, Fariborz; Mehrabi, Behzad; Monfaredi, Behzad; Friedl, Gertrude

    2015-04-01

    The determination of metamorphic conditions and of its age is critical to the understanding of the mountain belt formation as metamorphism is an expression of subduction or plate collision. In this study, we report the metamorphic evolution, preliminary Ar-Ar mineral ages and structures from two amphibolite-grade metamorphic units of the Dorud-Azna region in the central part of Sanandaj-Sirjan metamorphic zone and discuss the tectonic implications. The Sanandaj-Sirjan metamorphic zone is nearly parallel to the Main Zagros Reverse Fault and is located above the Neotethyan ophiolitic suture. Structural studies and our previous U-Pb zircon dating work demonstrated that the area comprise three metamorphosed tectonic units, which are from footwall to hangingwall: (1) The Triassic June complex is metamorphosed within greenschist facies conditions, overlain by (2) the amphibolite-grade metamorphic Panafrican Galeh-Doz orthogneiss, which is intruded by some mafic dykes, and (3) the Amphibolite-Metagabbro unit with Carboniferous metagabbro bodies. To the East, the Darijune gabbro intruded within the Permian Kuh-e-June Marble and the mentioned two other metamorphic units. The granitic Galeh-Doz orthogneiss displays two different P-T conditions. The best average estimates for the magmatic mineral assemblage (plagioclase core + amphibole core + K-feldspar + quartz) range between 675 and 710 °C and 3.7 and 4.2 kbar, whilst the temperature of 530 and 625 °C and pressure of 0.7 to 2.8 kbar is consistent with the first metamorphic mineral assemblage. Ar-Ar amphibole ages from the Galeh-Doz orthogneiss give plateau-like steps between 260 and 270 Ma. We interpret this age as the cooling age after an amphibolite facies-grade metamorphism. An amphibole from relatively well preserved dyke within the Galeh-Doz orthogneiss gives staircase pattern with an age of 261 ± 3 Ma in the first step considered similarly as a metamorphic overprint in metamorphic rocks, whereas plateau-like steps

  11. Awareness and use of caffeine by athletes competing at the 2005 Ironman Triathlon World Championships.

    PubMed

    Desbrow, Ben; Leveritt, Michael

    2006-10-01

    This study assessed the knowledge, prevalence, and quantity of caffeine use by athletes competing at the 2005 Ironman Triathlon World Championships. Caffeine-related questionnaires were self-administered to 140 (105 male and 35 female, 40.3 +/- 10.7 y) athletes representing 16 countries. Fifty of these athletes further consented to immediate post-race blood samples for analysis of plasma caffeine and paraxanthine using high-performance liquid chromatography (HPLC). Seventy-two percent of 70 athletes correctly identified caffeine as being an unrestricted substance in triathlon. The majority of athletes [125 (89%)] were planning on using a caffeinated substance immediately prior to or throughout the race. Cola drinks (78%), caffeinated gels (42%), coffee (usually pre-race) (37%), energy drinks (13%), and NoDoz tablets (9%) were the most popular caffeinated choices. Mean +/- standard deviation (and range) post race plasma caffeine and paraxanthine levels were 22.3 +/- 20 micromol/L (1.7 to 98.4) and 9.4 +/- 6 micromol/L (1.8 to 28.9), respectively. Seven athletes (14%) finished with plasma caffeine levels > or = 40 micromol/L. Plasma values from elite athletes did not differ from age group competitors. Despite the prevalence of its consumption and the training experience of this athletic group, over one quarter of athletes remained either confused or uninformed about caffeine's legality. Levels of plasma caffeine taken immediately post race indicated that athletes typically finish with quantities of caffeine that have been shown to improve endurance performance (i.e., approximately 20 micromol/L or a dose of > or = 3 mg/kg body weight). PMID:17240785

  12. Awareness and use of caffeine by athletes competing at the 2005 Ironman Triathlon World Championships.

    PubMed

    Desbrow, Ben; Leveritt, Michael

    2006-10-01

    This study assessed the knowledge, prevalence, and quantity of caffeine use by athletes competing at the 2005 Ironman Triathlon World Championships. Caffeine-related questionnaires were self-administered to 140 (105 male and 35 female, 40.3 +/- 10.7 y) athletes representing 16 countries. Fifty of these athletes further consented to immediate post-race blood samples for analysis of plasma caffeine and paraxanthine using high-performance liquid chromatography (HPLC). Seventy-two percent of 70 athletes correctly identified caffeine as being an unrestricted substance in triathlon. The majority of athletes [125 (89%)] were planning on using a caffeinated substance immediately prior to or throughout the race. Cola drinks (78%), caffeinated gels (42%), coffee (usually pre-race) (37%), energy drinks (13%), and NoDoz tablets (9%) were the most popular caffeinated choices. Mean +/- standard deviation (and range) post race plasma caffeine and paraxanthine levels were 22.3 +/- 20 micromol/L (1.7 to 98.4) and 9.4 +/- 6 micromol/L (1.8 to 28.9), respectively. Seven athletes (14%) finished with plasma caffeine levels > or = 40 micromol/L. Plasma values from elite athletes did not differ from age group competitors. Despite the prevalence of its consumption and the training experience of this athletic group, over one quarter of athletes remained either confused or uninformed about caffeine's legality. Levels of plasma caffeine taken immediately post race indicated that athletes typically finish with quantities of caffeine that have been shown to improve endurance performance (i.e., approximately 20 micromol/L or a dose of > or = 3 mg/kg body weight).

  13. The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats.

    PubMed

    Khan, Nadia; Saad, Ali; Nurulain, Syed M; Darras, Fouad H; Decker, Michael; Sadek, Bassem

    2016-01-15

    Both the histamine H3 receptor (H3R) and acetylcholine esterase (AChE) are involved in the regulation of release and metabolism of acetylcholine and several other central neurotransmitters. Therefore, dual-active H3R antagonists and AChE inhibitors (AChEIs) have shown in several studies to hold promise to treat cognitive disorders like Alzheimer's disease (AD). The novel dual-acting H3R antagonist and AChEI 7-(3-(piperidin-1-yl)propoxy)-1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline (UW-MD-71) with excellent selectivity profiles over both the three other HRs as well as the AChE's isoenzyme butyrylcholinesterase (BChE) shows high and balanced in vitro affinities at both H3R and AChE with IC50 of 33.9nM and hH3R antagonism with Ki of 76.2nM, respectively. In the present study, the effects of UW-MD-71 (1.25-5mg/kg, i.p.) on acquisition, consolidation, and retrieval in a one-trial inhibitory avoidance task in male rats were investigated applying donepezil (DOZ) and pitolisant (PIT) as reference drugs. Furthermore, the effects of UW-MD-71 on memory deficits induced by the non-competitive N-methyl-d-aspartate (NMDA) antagonist dizocilpine (DIZ) were tested. Our results indicate that administration of UW-MD-71 before the test session dose-dependently increased performance and enhanced procognitive effect on retrieval. However neither pre- nor post-training acute systemic administration of UW-MD-71 facilitated acquisition or consolidation. More importantly, UW-MD-71 (2.5mg/kg, i.p.) ameliorated the DIZ-induced amnesic effects. Furthermore, the procognitive activity of UW-MD-71 in retrieval was completely reversed and partly abrogated in DIZ-induced amnesia when rats were pretreated with the centrally-acting H2R antagonist zolantidine (ZOL), but not with the CNS penetrant H1R antagonist pyrilamine (PYR). These results demonstrate the procognitive effects of UW-MD-71 in two in vivo memory models, and are to our knowledge the first demonstration in vivo that a potent dual

  14. The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats.

    PubMed

    Sadek, Bassem; Khan, Nadia; Darras, Fouad H; Pockes, Steffen; Decker, Michael

    2016-10-15

    Both the acetylcholine esterase (AChE) and the histamine H3 receptor (H3R) are involved in the metabolism and modulation of acetylcholine release and numerous other centrally acting neurotransmitters. Hence, dual-active AChE inhibitors (AChEIs) and H3R antagonists hold potential to treat cognitive disorders like Alzheimer's disease (AD). The novel dual-acting AChEI and H3R antagonist 7-(3-(piperidin-1-yl)propoxy)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one (UW-MD-72) shows excellent selectivity profiles over the AChE's isoenzyme butyrylcholinesterase (BChE) as well as high and balanced in-vitro affinities at both AChE and hH3R with IC50 of 5.4μM on hAChE and hH3R antagonism with Ki of 2.54μM, respectively. In the current study, the effects of UW-MD-72 (1.25, 2.5, and 5mg/kg, i.p.) on memory deficits induced by the muscarinic cholinergic antagonist scopolamine (SCO) and the non-competitive N-methyl-d-aspartate (NMDA) antagonist dizocilpine (DIZ) were investigated in a step-through type passive avoidance paradigm in adult male rats applying donepezil (DOZ) and pitolisant (PIT) as reference drugs. The results observed show that SCO (2mg/kg, i.p.) and DIZ (0.1mg/kg, i.p.) significantly impaired learning and memory in rats. However, acute systemic administration of UW-MD-72 significantly ameliorated the SCO- and DIZ-induced amnesic effects. Furthermore, the ameliorating activity of UW-MD-72 (1.25mg/kg, i.p.) in DIZ-induced amnesia was partly reversed when rats were pretreated with the centrally-acting H2R antagonist zolantidine (ZOL, 10mg/kg, i.p.), but not with the CNS penetrant H1R antagonist pyrilamine (PYR, 10mg/kg, i.p.). Moreover, ameliorative effect of UW-MD-72 (1.25mg/kg, i.p.) in DIZ-induced amnesia was strongly reversed when rats were pretreated with a combination of ZOL (10mg/kg, i.p.) and SCO (1.0mg/kg, i.p.), indicating that these memory enhancing effects were, in addition to other neural circuits, observed through histaminergic H2R as well as