Water underground

NASA Astrophysics Data System (ADS)

de Graaf, Inge

2015-04-01

The world's largest assessable source of freshwater is hidden underground, but we do not know what is happening to it yet. In many places of the world groundwater is abstracted at unsustainable rates: more water is used than being recharged, leading to decreasing river discharges and declining groundwater levels. It is predicted that for many regions of the world unsustainable water use will increase, due to increasing human water use under changing climate. It would not be long before shortage causes widespread droughts and the first water war begins. Improving our knowledge about our hidden water is the first step to stop this. The world largest aquifers are mapped, but these maps do not mention how much water they contain or how fast water levels decline. If we can add a third dimension to the aquifer maps, so a thickness, and add geohydrological information we can estimate how much water is stored. Also data on groundwater age and how fast it is refilled is needed to predict the impact of human water use and climate change on the groundwater resource.

Cue-type manipulation dissociates two types of task set inhibition: backward inhibition and competitor rule suppression.

PubMed

Regev, Shirley; Meiran, Nachshon

2016-07-01

Backward inhibition (BI) reflects the suppression of a recently abandoned task set to allow for smooth transition to a new task even when the rules do not generate a response conflict. Competitor rule suppression (CRS) reflects the inhibition/suppression of irrelevant task rules when these rules generate a response conflict even if they have not recently been abandoned. We assessed whether BI and CRS are differentially affected by the difficulty in retrieving category-response mappings from memory. Retrieval demands were manipulated via the information provided by the task cues, which either indicated the relevant dimension (dimension cues; "color") or the relevant dimension with its category-to-key mapping (mapping cues; "red green", indicating that "red" and "green" go with the left/right responses, respectively). CRS was larger with dimension compared to mapping cues when cue-type varied between groups and was larger after trials involving dimension cues when cue-type varied on a trial-by-trial basis. In contrast, BI was not influenced by cue-type. These results suggest that task switching involve at least two distinct inhibitory processes, with CRS being related to the ease of retrieval of category-response mappings from memory.

Spatially encoded phase-contrast MRI-3D MRI movies of 1D and 2D structures at millisecond resolution.

PubMed

Merboldt, Klaus-Dietmar; Uecker, Martin; Voit, Dirk; Frahm, Jens

2011-10-01

This work demonstrates that the principles underlying phase-contrast MRI may be used to encode spatial rather than flow information along a perpendicular dimension, if this dimension contains an MRI-visible object at only one spatial location. In particular, the situation applies to 3D mapping of curved 2D structures which requires only two projection images with different spatial phase-encoding gradients. These phase-contrast gradients define the field of view and mean spin-density positions of the object in the perpendicular dimension by respective phase differences. When combined with highly undersampled radial fast low angle shot (FLASH) and image reconstruction by regularized nonlinear inversion, spatial phase-contrast MRI allows for dynamic 3D mapping of 2D structures in real time. First examples include 3D MRI movies of the acting human hand at a temporal resolution of 50 ms. With an even simpler technique, 3D maps of curved 1D structures may be obtained from only three acquisitions of a frequency-encoded MRI signal with two perpendicular phase encodings. Here, 3D MRI movies of a rapidly rotating banana were obtained at 5 ms resolution or 200 frames per second. In conclusion, spatial phase-contrast 3D MRI of 2D or 1D structures is respective two or four orders of magnitude faster than conventional 3D MRI. Copyright © 2011 Wiley-Liss, Inc.

A brief review on the history of human functional near-infrared spectroscopy (fNIRS) development and fields of application.

PubMed

Ferrari, Marco; Quaresima, Valentina

2012-11-01

This review is aimed at celebrating the upcoming 20th anniversary of the birth of human functional near-infrared spectroscopy (fNIRS). After the discovery in 1992 that the functional activation of the human cerebral cortex (due to oxygenation and hemodynamic changes) can be explored by NIRS, human functional brain mapping research has gained a new dimension. fNIRS or optical topography, or near-infrared imaging or diffuse optical imaging is used mainly to detect simultaneous changes in optical properties of the human cortex from multiple measurement sites and displays the results in the form of a map or image over a specific area. In order to place current fNIRS research in its proper context, this paper presents a brief historical overview of the events that have shaped the present status of fNIRS. In particular, technological progresses of fNIRS are highlighted (i.e., from single-site to multi-site functional cortical measurements (images)), introduction of the commercial multi-channel systems, recent commercial wireless instrumentation and more advanced prototypes. Copyright © 2012 Elsevier Inc. All rights reserved.

Separating pitch chroma and pitch height in the human brain

PubMed Central

Warren, J. D.; Uppenkamp, S.; Patterson, R. D.; Griffiths, T. D.

2003-01-01

Musicians recognize pitch as having two dimensions. On the keyboard, these are illustrated by the octave and the cycle of notes within the octave. In perception, these dimensions are referred to as pitch height and pitch chroma, respectively. Pitch chroma provides a basis for presenting acoustic patterns (melodies) that do not depend on the particular sound source. In contrast, pitch height provides a basis for segregation of notes into streams to separate sound sources. This paper reports a functional magnetic resonance experiment designed to search for distinct mappings of these two types of pitch change in the human brain. The results show that chroma change is specifically represented anterior to primary auditory cortex, whereas height change is specifically represented posterior to primary auditory cortex. We propose that tracking of acoustic information streams occurs in anterior auditory areas, whereas the segregation of sound objects (a crucial aspect of auditory scene analysis) depends on posterior areas. PMID:12909719

Separating pitch chroma and pitch height in the human brain.

PubMed

Warren, J D; Uppenkamp, S; Patterson, R D; Griffiths, T D

2003-08-19

Musicians recognize pitch as having two dimensions. On the keyboard, these are illustrated by the octave and the cycle of notes within the octave. In perception, these dimensions are referred to as pitch height and pitch chroma, respectively. Pitch chroma provides a basis for presenting acoustic patterns (melodies) that do not depend on the particular sound source. In contrast, pitch height provides a basis for segregation of notes into streams to separate sound sources. This paper reports a functional magnetic resonance experiment designed to search for distinct mappings of these two types of pitch change in the human brain. The results show that chroma change is specifically represented anterior to primary auditory cortex, whereas height change is specifically represented posterior to primary auditory cortex. We propose that tracking of acoustic information streams occurs in anterior auditory areas, whereas the segregation of sound objects (a crucial aspect of auditory scene analysis) depends on posterior areas.

Integrating physical and genetic maps: from genomes to interaction networks

PubMed Central

Beyer, Andreas; Bandyopadhyay, Sourav; Ideker, Trey

2009-01-01

Physical and genetic mapping data have become as important to network biology as they once were to the Human Genome Project. Integrating physical and genetic networks currently faces several challenges: increasing the coverage of each type of network; establishing methods to assemble individual interaction measurements into contiguous pathway models; and annotating these pathways with detailed functional information. A particular challenge involves reconciling the wide variety of interaction types that are currently available. For this purpose, recent studies have sought to classify genetic and physical interactions along several complementary dimensions, such as ordered versus unordered, alleviating versus aggravating, and first versus second degree. PMID:17703239

The Effect of Teaching Vocabulary through Semantic Mapping on EFL Learners' Awareness of the Affective Dimensions of Deep Vocabulary Knowledge

ERIC Educational Resources Information Center

Nilforoushan, Somayeh

2012-01-01

This study focused on the effect of teaching vocabulary through semantic mapping on the awareness of two affective dimensions, evaluation and potency dimensions of deep vocabulary knowledge as well as the general vocabulary knowledge of EFL students. Sixty intermediate EFL female adult learners participated in this study; they were chosen among 90…

Exploring the Structure of Spatial Representations

PubMed Central

Madl, Tamas; Franklin, Stan; Chen, Ke; Trappl, Robert; Montaldi, Daniela

2016-01-01

It has been suggested that the map-like representations that support human spatial memory are fragmented into sub-maps with local reference frames, rather than being unitary and global. However, the principles underlying the structure of these ‘cognitive maps’ are not well understood. We propose that the structure of the representations of navigation space arises from clustering within individual psychological spaces, i.e. from a process that groups together objects that are close in these spaces. Building on the ideas of representational geometry and similarity-based representations in cognitive science, we formulate methods for learning dissimilarity functions (metrics) characterizing participants’ psychological spaces. We show that these learned metrics, together with a probabilistic model of clustering based on the Bayesian cognition paradigm, allow prediction of participants’ cognitive map structures in advance. Apart from insights into spatial representation learning in human cognition, these methods could facilitate novel computational tools capable of using human-like spatial concepts. We also compare several features influencing spatial memory structure, including spatial distance, visual similarity and functional similarity, and report strong correlations between these dimensions and the grouping probability in participants’ spatial representations, providing further support for clustering in spatial memory. PMID:27347681

NeatMap--non-clustering heat map alternatives in R.

PubMed

Rajaram, Satwik; Oono, Yoshi

2010-01-22

The clustered heat map is the most popular means of visualizing genomic data. It compactly displays a large amount of data in an intuitive format that facilitates the detection of hidden structures and relations in the data. However, it is hampered by its use of cluster analysis which does not always respect the intrinsic relations in the data, often requiring non-standardized reordering of rows/columns to be performed post-clustering. This sometimes leads to uninformative and/or misleading conclusions. Often it is more informative to use dimension-reduction algorithms (such as Principal Component Analysis and Multi-Dimensional Scaling) which respect the topology inherent in the data. Yet, despite their proven utility in the analysis of biological data, they are not as widely used. This is at least partially due to the lack of user-friendly visualization methods with the visceral impact of the heat map. NeatMap is an R package designed to meet this need. NeatMap offers a variety of novel plots (in 2 and 3 dimensions) to be used in conjunction with these dimension-reduction techniques. Like the heat map, but unlike traditional displays of such results, it allows the entire dataset to be displayed while visualizing relations between elements. It also allows superimposition of cluster analysis results for mutual validation. NeatMap is shown to be more informative than the traditional heat map with the help of two well-known microarray datasets. NeatMap thus preserves many of the strengths of the clustered heat map while addressing some of its deficiencies. It is hoped that NeatMap will spur the adoption of non-clustering dimension-reduction algorithms.

Mapping the human atria with optical coherence tomography

NASA Astrophysics Data System (ADS)

Lye, Theresa H.; Gan, Yu; Hendon, Christine P.

2017-02-01

Atrial structure plays an important role in the mechanisms of atrial disease. However, detailed imaging of human atria remains limited due to many imaging modalities lacking sufficient resolution. We propose the use of optical coherence tomography (OCT), which has micrometer resolution and millimeter-scale imaging depth well-suited for the atria, combined with image stitching algorithms, to develop large, detailed atria image maps. Human atria samples (n = 7) were obtained under approved protocols from the National Disease Research Interchange (NDRI). One right atria sample was imaged using an ultrahigh-resolution spectral domain OCT system, with 5.52 and 2.72 μm lateral and axial resolution in air, respectively, and 1.78 mm imaging depth. Six left atria and five pulmonary vein samples were imaged using the spectral domain OCT system, Telesto I (Thorlabs GmbH, Germany) with 15 and 6.5 μm lateral and axial resolution in air, respectively, and 2.51 mm imaging depth. Overlapping image volumes were obtained from areas of the human left and right atria and the pulmonary veins. Regions of collagen, adipose, and myocardium could be identified within the OCT images. Image stitching was applied to generate fields of view with side dimensions up to about 3 cm. This study established steps towards mapping large regions of the human atria and pulmonary veins in high resolution using OCT.

Time Is Not Space: Core Computations and Domain-Specific Networks for Mental Travels.

PubMed

Gauthier, Baptiste; van Wassenhove, Virginie

2016-11-23

Humans can consciously project themselves in the future and imagine themselves at different places. Do mental time travel and mental space navigation abilities share common cognitive and neural mechanisms? To test this, we recorded fMRI while participants mentally projected themselves in time or in space (e.g., 9 years ago, in Paris) and ordered historical events from their mental perspective. Behavioral patterns were comparable for mental time and space and shaped by self-projection and by the distance of historical events to the mental position of the self, suggesting the existence of egocentric mapping in both dimensions. Nonetheless, self-projection in space engaged the medial and lateral parietal cortices, whereas self-projection in time engaged a widespread parietofrontal network. Moreover, while a large distributed network was found for spatial distances, temporal distances specifically engaged the right inferior parietal cortex and the anterior insula. Across these networks, a robust overlap was only found in a small region of the inferior parietal lobe, adding evidence for its role in domain-general egocentric mapping. Our findings suggest that mental travel in time or space capitalizes on egocentric remapping and on distance computation, which are implemented in distinct dimension-specific cortical networks converging in inferior parietal lobe. As humans, we can consciously imagine ourselves at a different time (mental time travel) or at a different place (mental space navigation). Are such abilities domain-general, or are the temporal and spatial dimensions of our conscious experience separable? Here, we tested the hypothesis that mental time travel and mental space navigation required the egocentric remapping of events, including the estimation of their distances to the self. We report that, although both remapping and distance computation are foundational for the processing of the temporal and spatial dimensions of our conscious experience, their neuroanatomical implementations were clearly dissociable and engaged distinct parietal and parietofrontal networks for mental space navigation and mental time travel, respectively. Copyright © 2016 the authors 0270-6474/16/3611891-13$15.00/0.

Quantifying and Qualifying USGS ShakeMap Uncertainty

USGS Publications Warehouse

Wald, David J.; Lin, Kuo-Wan; Quitoriano, Vincent

2008-01-01

We describe algorithms for quantifying and qualifying uncertainties associated with USGS ShakeMap ground motions. The uncertainty values computed consist of latitude/longitude grid-based multiplicative factors that scale the standard deviation associated with the ground motion prediction equation (GMPE) used within the ShakeMap algorithm for estimating ground motions. The resulting grid-based 'uncertainty map' is essential for evaluation of losses derived using ShakeMaps as the hazard input. For ShakeMap, ground motion uncertainty at any point is dominated by two main factors: (i) the influence of any proximal ground motion observations, and (ii) the uncertainty of estimating ground motions from the GMPE, most notably, elevated uncertainty due to initial, unconstrained source rupture geometry. The uncertainty is highest for larger magnitude earthquakes when source finiteness is not yet constrained and, hence, the distance to rupture is also uncertain. In addition to a spatially-dependant, quantitative assessment, many users may prefer a simple, qualitative grading for the entire ShakeMap. We developed a grading scale that allows one to quickly gauge the appropriate level of confidence when using rapidly produced ShakeMaps as part of the post-earthquake decision-making process or for qualitative assessments of archived or historical earthquake ShakeMaps. We describe an uncertainty letter grading ('A' through 'F', for high to poor quality, respectively) based on the uncertainty map. A middle-range ('C') grade corresponds to a ShakeMap for a moderate-magnitude earthquake suitably represented with a point-source location. Lower grades 'D' and 'F' are assigned for larger events (M>6) where finite-source dimensions are not yet constrained. The addition of ground motion observations (or observed macroseismic intensities) reduces uncertainties over data-constrained portions of the map. Higher grades ('A' and 'B') correspond to ShakeMaps with constrained fault dimensions and numerous stations, depending on the density of station/data coverage. Due to these dependencies, the letter grade can change with subsequent ShakeMap revisions if more data are added or when finite-faulting dimensions are added. We emphasize that the greatest uncertainties are associated with unconstrained source dimensions for large earthquakes where the distance term in the GMPE is most uncertain; this uncertainty thus scales with magnitude (and consequently rupture dimension). Since this distance uncertainty produces potentially large uncertainties in ShakeMap ground-motion estimates, this factor dominates over compensating constraints for all but the most dense station distributions.

The fractal based analysis of human face and DNA variations during aging.

PubMed

Namazi, Hamidreza; Akrami, Amin; Hussaini, Jamal; Silva, Osmar N; Wong, Albert; Kulish, Vladimir V

2017-01-16

Human DNA is the main unit that shapes human characteristics and features such as behavior. Thus, it is expected that changes in DNA (DNA mutation) influence human characteristics and features. Face is one of the human features which is unique and also dependent on his gen. In this paper, for the first time we analyze the variations of human DNA and face simultaneously. We do this job by analyzing the fractal dimension of DNA walk and face during human aging. The results of this study show the human DNA and face get more complex by aging. These complexities are mapped on fractal exponents of DNA walk and human face. The method discussed in this paper can be further developed in order to investigate the direct influence of DNA mutation on the face variations during aging, and accordingly making a model between human face fractality and the complexity of DNA walk.

Time Series Analysis OF SAR Image Fractal Maps: The Somma-Vesuvio Volcanic Complex Case Study

NASA Astrophysics Data System (ADS)

Pepe, Antonio; De Luca, Claudio; Di Martino, Gerardo; Iodice, Antonio; Manzo, Mariarosaria; Pepe, Susi; Riccio, Daniele; Ruello, Giuseppe; Sansosti, Eugenio; Zinno, Ivana

2016-04-01

The fractal dimension is a significant geophysical parameter describing natural surfaces representing the distribution of the roughness over different spatial scale; in case of volcanic structures, it has been related to the specific nature of materials and to the effects of active geodynamic processes. In this work, we present the analysis of the temporal behavior of the fractal dimension estimates generated from multi-pass SAR images relevant to the Somma-Vesuvio volcanic complex (South Italy). To this aim, we consider a Cosmo-SkyMed data-set of 42 stripmap images acquired from ascending orbits between October 2009 and December 2012. Starting from these images, we generate a three-dimensional stack composed by the corresponding fractal maps (ordered according to the acquisition dates), after a proper co-registration. The time-series of the pixel-by-pixel estimated fractal dimension values show that, over invariant natural areas, the fractal dimension values do not reveal significant changes; on the contrary, over urban areas, it correctly assumes values outside the natural surfaces fractality range and show strong fluctuations. As a final result of our analysis, we generate a fractal map that includes only the areas where the fractal dimension is considered reliable and stable (i.e., whose standard deviation computed over the time series is reasonably small). The so-obtained fractal dimension map is then used to identify areas that are homogeneous from a fractal viewpoint. Indeed, the analysis of this map reveals the presence of two distinctive landscape units corresponding to the Mt. Vesuvio and Gran Cono. The comparison with the (simplified) geological map clearly shows the presence in these two areas of volcanic products of different age. The presented fractal dimension map analysis demonstrates the ability to get a figure about the evolution degree of the monitored volcanic edifice and can be profitably extended in the future to other volcanic systems with very distinctive characteristics, with the aim to perform land classification, such as the identification of areas characterized by similar soil use, slopes and exposures.

Simplification and Shift in Cognition of Political Difference: Applying the Geometric Modeling to the Analysis of Semantic Similarity Judgment

PubMed Central

Kato, Junko; Okada, Kensuke

2011-01-01

Perceiving differences by means of spatial analogies is intrinsic to human cognition. Multi-dimensional scaling (MDS) analysis based on Minkowski geometry has been used primarily on data on sensory similarity judgments, leaving judgments on abstractive differences unanalyzed. Indeed, analysts have failed to find appropriate experimental or real-life data in this regard. Our MDS analysis used survey data on political scientists' judgments of the similarities and differences between political positions expressed in terms of distance. Both distance smoothing and majorization techniques were applied to a three-way dataset of similarity judgments provided by at least seven experts on at least five parties' positions on at least seven policies (i.e., originally yielding 245 dimensions) to substantially reduce the risk of local minima. The analysis found two dimensions, which were sufficient for mapping differences, and fit the city-block dimensions better than the Euclidean metric in all datasets obtained from 13 countries. Most city-block dimensions were highly correlated with the simplified criterion (i.e., the left–right ideology) for differences that are actually used in real politics. The isometry of the city-block and dominance metrics in two-dimensional space carries further implications. More specifically, individuals may pay attention to two dimensions (if represented in the city-block metric) or focus on a single dimension (if represented in the dominance metric) when judging differences between the same objects. Switching between metrics may be expected to occur during cognitive processing as frequently as the apparent discontinuities and shifts in human attention that may underlie changing judgments in real situations occur. Consequently, the result has extended strong support for the validity of the geometric models to represent an important social cognition, i.e., the one of political differences, which is deeply rooted in human nature. PMID:21673959

Simplification and shift in cognition of political difference: applying the geometric modeling to the analysis of semantic similarity judgment.

PubMed

Kato, Junko; Okada, Kensuke

2011-01-01

Perceiving differences by means of spatial analogies is intrinsic to human cognition. Multi-dimensional scaling (MDS) analysis based on Minkowski geometry has been used primarily on data on sensory similarity judgments, leaving judgments on abstractive differences unanalyzed. Indeed, analysts have failed to find appropriate experimental or real-life data in this regard. Our MDS analysis used survey data on political scientists' judgments of the similarities and differences between political positions expressed in terms of distance. Both distance smoothing and majorization techniques were applied to a three-way dataset of similarity judgments provided by at least seven experts on at least five parties' positions on at least seven policies (i.e., originally yielding 245 dimensions) to substantially reduce the risk of local minima. The analysis found two dimensions, which were sufficient for mapping differences, and fit the city-block dimensions better than the Euclidean metric in all datasets obtained from 13 countries. Most city-block dimensions were highly correlated with the simplified criterion (i.e., the left-right ideology) for differences that are actually used in real politics. The isometry of the city-block and dominance metrics in two-dimensional space carries further implications. More specifically, individuals may pay attention to two dimensions (if represented in the city-block metric) or focus on a single dimension (if represented in the dominance metric) when judging differences between the same objects. Switching between metrics may be expected to occur during cognitive processing as frequently as the apparent discontinuities and shifts in human attention that may underlie changing judgments in real situations occur. Consequently, the result has extended strong support for the validity of the geometric models to represent an important social cognition, i.e., the one of political differences, which is deeply rooted in human nature.

Material wealth in 3D: Mapping multiple paths to prosperity in low- and middle- income countries.

PubMed

Hruschka, Daniel J; Hadley, Craig; Hackman, Joseph

2017-01-01

Material wealth is a key factor shaping human development and well-being. Every year, hundreds of studies in social science and policy fields assess material wealth in low- and middle-income countries assuming that there is a single dimension by which households can move from poverty to prosperity. However, a one-dimensional model may miss important kinds of prosperity, particularly in countries where traditional subsistence-based livelihoods coexist with modern cash economies. Using multiple correspondence analysis to analyze representative household data from six countries-Nepal, Bangladesh, Ethiopia, Kenya, Tanzania and Guatemala-across three world regions, we identify a number of independent dimension of wealth, each with a clear link to locally relevant pathways to success in cash and agricultural economies. In all cases, the first dimension identified by this approach replicates standard one-dimensional estimates and captures success in cash economies. The novel dimensions we identify reflect success in different agricultural sectors and are independently associated with key benchmarks of food security and human growth, such as adult body mass index and child height. The multidimensional models of wealth we describe here provide new opportunities for examining the causes and consequences of wealth inequality that go beyond success in cash economies, for tracing the emergence of hybrid pathways to prosperity, and for assessing how these different pathways to economic success carry different health risks and social opportunities.

Material wealth in 3D: Mapping multiple paths to prosperity in low- and middle- income countries

PubMed Central

Hadley, Craig; Hackman, Joseph

2017-01-01

Material wealth is a key factor shaping human development and well-being. Every year, hundreds of studies in social science and policy fields assess material wealth in low- and middle-income countries assuming that there is a single dimension by which households can move from poverty to prosperity. However, a one-dimensional model may miss important kinds of prosperity, particularly in countries where traditional subsistence-based livelihoods coexist with modern cash economies. Using multiple correspondence analysis to analyze representative household data from six countries—Nepal, Bangladesh, Ethiopia, Kenya, Tanzania and Guatemala—across three world regions, we identify a number of independent dimension of wealth, each with a clear link to locally relevant pathways to success in cash and agricultural economies. In all cases, the first dimension identified by this approach replicates standard one-dimensional estimates and captures success in cash economies. The novel dimensions we identify reflect success in different agricultural sectors and are independently associated with key benchmarks of food security and human growth, such as adult body mass index and child height. The multidimensional models of wealth we describe here provide new opportunities for examining the causes and consequences of wealth inequality that go beyond success in cash economies, for tracing the emergence of hybrid pathways to prosperity, and for assessing how these different pathways to economic success carry different health risks and social opportunities. PMID:28886176

Mapping the Sensitivity of the Public Emotion to the Movement of STOCK Market Value: a Case Study of Manhattan

NASA Astrophysics Data System (ADS)

Kang, Y.; Wang, J.; Wang, Y.; Angsuesser, S.; Fei, T.

2017-09-01

We examined whether emotion expressed by users in social media can be influenced by stock market index or can predict the fluctuation of the stock market index. We collected the emotion data by using face detection technology and emotion cognition services for photos uploaded to Flickr. Each face's emotion was described in 8 dimensions the location was also recorded. An emotion score index was defined based on the combination of all 8 dimensions of emotion calculated by principal component analysis. The correlation coefficients between the stock market values and emotion scores are significant (R > 0.59 with p < 0.01). Using Granger Causality analysis for cause and effect detection, we found that users' emotion is influenced by stock market value change. A multiple linear regression model was established (R-square = 0.76) to explore the potential factors that influence the emotion score. Finally, a sensitivity map was created to show sensitive areas where human emotion is easily affected by the stock market changes. We concluded that in Manhattan region: (1) there is an obvious relationship between human emotion and stock market fluctuation; (2) emotion change follows the movements of the stock market; (3) the Times Square and Broadway Theatre are the most sensitive regions in terms of public emotional reaction to the economy represented by stock value.

Psychometric and Edumetric Validity of Dimensions of Geomorphological Knowledge Which Are Tapped by Concept Mapping.

ERIC Educational Resources Information Center

Hoz, Ron; Bowman, Dan; Chacham, Tova

1997-01-01

Students (N=14) in a geomorphology course took an objective geomorphology test, the tree construction task, and the Standardized Concept Structuring Analysis Technique (SConSAT) version of concept mapping. Results suggest that the SConSAT knowledge structure dimensions have moderate to good construct validity. Contains 82 references. (DDR)

Systems and Methods for Data Visualization Using Three-Dimensional Displays

NASA Technical Reports Server (NTRS)

Davidoff, Scott (Inventor); Djorgovski, Stanislav G. (Inventor); Estrada, Vicente (Inventor); Donalek, Ciro (Inventor)

2017-01-01

Data visualization systems and methods for generating 3D visualizations of a multidimensional data space are described. In one embodiment a 3D data visualization application directs a processing system to: load a set of multidimensional data points into a visualization table; create representations of a set of 3D objects corresponding to the set of data points; receive mappings of data dimensions to visualization attributes; determine the visualization attributes of the set of 3D objects based upon the selected mappings of data dimensions to 3D object attributes; update a visibility dimension in the visualization table for each of the plurality of 3D object to reflect the visibility of each 3D object based upon the selected mappings of data dimensions to visualization attributes; and interactively render 3D data visualizations of the 3D objects within the virtual space from viewpoints determined based upon received user input.

ComVisMD - compact visualization of multidimensional data: experimenting with cricket players data

NASA Astrophysics Data System (ADS)

Dandin, Shridhar B.; Ducassé, Mireille

2018-03-01

Database information is multidimensional and often displayed in tabular format (row/column display). Presented in aggregated form, multidimensional data can be used to analyze the records or objects. Online Analytical database Processing (OLAP) proposes mechanisms to display multidimensional data in aggregated forms. A choropleth map is a thematic map in which areas are colored in proportion to the measurement of a statistical variable being displayed, such as population density. They are used mostly for compact graphical representation of geographical information. We propose a system, ComVisMD inspired by choropleth map and the OLAP cube to visualize multidimensional data in a compact way. ComVisMD displays multidimensional data like OLAP Cube, where we are mapping an attribute a (first dimension, e.g. year started playing cricket) in vertical direction, object coloring based on b (second dimension, e.g. batting average), mapping varying-size circles based on attribute c (third dimension, e.g. highest score), mapping numbers based on attribute d (fourth dimension, e.g. matches played). We illustrate our approach on cricket players data, namely on two tables Country and Player. They have a large number of rows and columns: 246 rows and 17 columns for players of one country. ComVisMD’s visualization reduces the size of the tabular display by a factor of about 4, allowing users to grasp more information at a time than the bare table display.

New type of chaos synchronization in discrete-time systems: the F-M synchronization

NASA Astrophysics Data System (ADS)

Ouannas, Adel; Grassi, Giuseppe; Karouma, Abdulrahman; Ziar, Toufik; Wang, Xiong; Pham, Viet-Thanh

2018-04-01

In this paper, a new type of synchronization for chaotic (hyperchaotic) maps with different dimensions is proposed. The novel scheme is called F - M synchronization, since it combines the inverse generalized synchronization (based on a functional relationship F) with the matrix projective synchronization (based on a matrix M). In particular, the proposed approach enables F - M synchronization with index d to be achieved between n-dimensional drive system map and m-dimensional response system map, where the synchronization index d corresponds to the dimension of the synchronization error. The technique, which exploits nonlinear controllers and Lyapunov stability theory, proves to be effective in achieving the F - M synchronization not only when the synchronization index d equals n or m, but even if the synchronization index d is larger than the map dimensions n and m. Finally, simulation results are reported, with the aim to illustrate the capabilities of the novel scheme proposed herein.

Dynamic microenvironments: the fourth dimension.

PubMed

Tibbitt, Mark W; Anseth, Kristi S

2012-11-14

The extracellular space, or cell microenvironment, choreographs cell behavior through myriad controlled signals, and aberrant cues can result in dysfunction and disease. For functional studies of human cell biology or expansion and delivery of cells for therapeutic purposes, scientists must decipher this intricate map of microenvironment biology and develop ways to mimic these functions in vitro. In this Perspective, we describe technologies for four-dimensional (4D) biology: cell-laden matrices engineered to recapitulate tissue and organ function in 3D space and over time.

Coupled skinny baker's maps and the Kaplan-Yorke conjecture

NASA Astrophysics Data System (ADS)

Gröger, Maik; Hunt, Brian R.

2013-09-01

The Kaplan-Yorke conjecture states that for ‘typical’ dynamical systems with a physical measure, the information dimension and the Lyapunov dimension coincide. We explore this conjecture in a neighborhood of a system for which the two dimensions do not coincide because the system consists of two uncoupled subsystems. We are interested in whether coupling ‘typically’ restores the equality of the dimensions. The particular subsystems we consider are skinny baker's maps, and we consider uni-directional coupling. For coupling in one of the possible directions, we prove that the dimensions coincide for a prevalent set of coupling functions, but for coupling in the other direction we show that the dimensions remain unequal for all coupling functions. We conjecture that the dimensions prevalently coincide for bi-directional coupling. On the other hand, we conjecture that the phenomenon we observe for a particular class of systems with uni-directional coupling, where the information and Lyapunov dimensions differ robustly, occurs more generally for many classes of uni-directionally coupled systems (also called skew-product systems) in higher dimensions.

Approaching Multidimensional Forms of Knowledge through Personal Meaning Mapping in Science Integrating Teaching outside the Classroom

ERIC Educational Resources Information Center

Hartmeyer, Rikke; Bølling, Mads; Bentsen, Peter

2017-01-01

Current research points to Personal Meaning Mapping (PMM) as a method useful in investigating students' prior and current science knowledge. However, studies investigating PMM as a method for exploring specific knowledge dimensions are lacking. Ensuring that students are able to access specific knowledge dimensions is important, especially in…

Simultaneous mapping of water shift and B1 (WASABI)-Application to field-Inhomogeneity correction of CEST MRI data.

PubMed

Schuenke, Patrick; Windschuh, Johannes; Roeloffs, Volkert; Ladd, Mark E; Bachert, Peter; Zaiss, Moritz

2017-02-01

Together with the development of MRI contrasts that are inherently small in their magnitude, increased magnetic field accuracy is also required. Hence, mapping of the static magnetic field (B 0 ) and the excitation field (B 1 ) is not only important to feedback shim algorithms, but also for postprocess contrast-correction procedures. A novel field-inhomogeneity mapping method is presented that allows simultaneous mapping of the water shift and B 1 (WASABI) using an off-resonant rectangular preparation pulse. The induced Rabi oscillations lead to a sinc-like spectrum in the frequency-offset dimension and allow for determination of B 0 by its symmetry axis and of B 1 by its oscillation frequency. Stability of the WASABI method with regard to the influences of T 1 , T 2 , magnetization transfer, and repetition time was investigated and its convergence interval was verified. B 0 and B 1 maps obtained simultaneously by means of WASABI in the human brain at 3 T and 7 T can compete well with maps obtained by standard methods. Finally, the method was applied successfully for B 0 and B 1 correction of chemical exchange saturation transfer MRI (CEST-MRI) data of the human brain. The proposed WASABI method yields a novel simultaneous B 0 and B 1 mapping within 1 min that is robust and easy to implement. Magn Reson Med 77:571-580, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

Heavenly Networks. Celestial Maps and Globes in Circulation between Artisans, Mathematicians, and Noblemen in Renaissance Europe.

PubMed

Gessner, Samuel

2015-01-01

The aim of this paper is to examine the iconography on a set of star charts by Albrecht Dürer (1515), and celestial globes by Caspar Vopel (1536) and Christoph Schissler (1575). The iconography on these instruments is conditioned by strong traditions which include not only the imagery on globes and planispheres (star charts), but also ancient literature about the constellations. Where this iconography departs from those traditions, the change had to do with humanism in the sixteenth century. This "humanistic" dimension is interwoven with other concerns that involve both "social" and "technical" motivations. The interplay of these three dimensions illustrates how the iconography on celestial charts and globes expresses some features of the shared knowledge and shared culture between artisans, mathematicians, and nobles in Renaissance Europe.

Creating Body Shapes From Verbal Descriptions by Linking Similarity Spaces.

PubMed

Hill, Matthew Q; Streuber, Stephan; Hahn, Carina A; Black, Michael J; O'Toole, Alice J

2016-11-01

Brief verbal descriptions of people's bodies (e.g., "curvy," "long-legged") can elicit vivid mental images. The ease with which these mental images are created belies the complexity of three-dimensional body shapes. We explored the relationship between body shapes and body descriptions and showed that a small number of words can be used to generate categorically accurate representations of three-dimensional bodies. The dimensions of body-shape variation that emerged in a language-based similarity space were related to major dimensions of variation computed directly from three-dimensional laser scans of 2,094 bodies. This relationship allowed us to generate three-dimensional models of people in the shape space using only their coordinates on analogous dimensions in the language-based description space. Human descriptions of photographed bodies and their corresponding models matched closely. The natural mapping between the spaces illustrates the role of language as a concise code for body shape that captures perceptually salient global and local body features. © The Author(s) 2016.

Can Mapping Algorithms Based on Raw Scores Overestimate QALYs Gained by Treatment? A Comparison of Mappings Between the Roland-Morris Disability Questionnaire and the EQ-5D-3L Based on Raw and Differenced Score Data.

PubMed

Madan, Jason; Khan, Kamran A; Petrou, Stavros; Lamb, Sarah E

2017-05-01

Mapping algorithms are increasingly being used to predict health-utility values based on responses or scores from non-preference-based measures, thereby informing economic evaluations. We explored whether predictions in the EuroQol 5-dimension 3-level instrument (EQ-5D-3L) health-utility gains from mapping algorithms might differ if estimated using differenced versus raw scores, using the Roland-Morris Disability Questionnaire (RMQ), a widely used health status measure for low back pain, as an example. We estimated algorithms mapping within-person changes in RMQ scores to changes in EQ-5D-3L health utilities using data from two clinical trials with repeated observations. We also used logistic regression models to estimate response mapping algorithms from these data to predict within-person changes in responses to each EQ-5D-3L dimension from changes in RMQ scores. Predicted health-utility gains from these mappings were compared with predictions based on raw RMQ data. Using differenced scores reduced the predicted health-utility gain from a unit decrease in RMQ score from 0.037 (standard error [SE] 0.001) to 0.020 (SE 0.002). Analysis of response mapping data suggests that the use of differenced data reduces the predicted impact of reducing RMQ scores across EQ-5D-3L dimensions and that patients can experience health-utility gains on the EQ-5D-3L 'usual activity' dimension independent from improvements captured by the RMQ. Mappings based on raw RMQ data overestimate the EQ-5D-3L health utility gains from interventions that reduce RMQ scores. Where possible, mapping algorithms should reflect within-person changes in health outcome and be estimated from datasets containing repeated observations if they are to be used to estimate incremental health-utility gains.

Integrating Databases with Maps: The Delivery of Cultural Data through TimeMap.

ERIC Educational Resources Information Center

Johnson, Ian

TimeMap is a unique integration of database management, metadata and interactive maps, designed to contextualise and deliver cultural data through maps. TimeMap extends conventional maps with the time dimension, creating and animating maps "on-the-fly"; delivers them as a kiosk application or embedded in Web pages; links flexibly to…

A comprehensive three-dimensional cortical map of vowel space.

PubMed

Scharinger, Mathias; Idsardi, William J; Poe, Samantha

2011-12-01

Mammalian cortex is known to contain various kinds of spatial encoding schemes for sensory information including retinotopic, somatosensory, and tonotopic maps. Tonotopic maps are especially interesting for human speech sound processing because they encode linguistically salient acoustic properties. In this study, we mapped the entire vowel space of a language (Turkish) onto cortical locations by using the magnetic N1 (M100), an auditory-evoked component that peaks approximately 100 msec after auditory stimulus onset. We found that dipole locations could be structured into two distinct maps, one for vowels produced with the tongue positioned toward the front of the mouth (front vowels) and one for vowels produced in the back of the mouth (back vowels). Furthermore, we found spatial gradients in lateral-medial, anterior-posterior, and inferior-superior dimensions that encoded the phonetic, categorical distinctions between all the vowels of Turkish. Statistical model comparisons of the dipole locations suggest that the spatial encoding scheme is not entirely based on acoustic bottom-up information but crucially involves featural-phonetic top-down modulation. Thus, multiple areas of excitation along the unidimensional basilar membrane are mapped into higher dimensional representations in auditory cortex.

A novel color image encryption scheme using alternate chaotic mapping structure

NASA Astrophysics Data System (ADS)

Wang, Xingyuan; Zhao, Yuanyuan; Zhang, Huili; Guo, Kang

2016-07-01

This paper proposes an color image encryption algorithm using alternate chaotic mapping structure. Initially, we use the R, G and B components to form a matrix. Then one-dimension logistic and two-dimension logistic mapping is used to generate a chaotic matrix, then iterate two chaotic mappings alternately to permute the matrix. For every iteration, XOR operation is adopted to encrypt plain-image matrix, then make further transformation to diffuse the matrix. At last, the encrypted color image is obtained from the confused matrix. Theoretical analysis and experimental results has proved the cryptosystem is secure and practical, and it is suitable for encrypting color images.

Development of a parametric kinematic model of the human hand and a novel robotic exoskeleton.

PubMed

Burton, T M W; Vaidyanathan, R; Burgess, S C; Turton, A J; Melhuish, C

2011-01-01

This paper reports the integration of a kinematic model of the human hand during cylindrical grasping, with specific focus on the accurate mapping of thumb movement during grasping motions, and a novel, multi-degree-of-freedom assistive exoskeleton mechanism based on this model. The model includes thumb maximum hyper-extension for grasping large objects (~> 50 mm). The exoskeleton includes a novel four-bar mechanism designed to reproduce natural thumb opposition and a novel synchro-motion pulley mechanism for coordinated finger motion. A computer aided design environment is used to allow the exoskeleton to be rapidly customized to the hand dimensions of a specific patient. Trials comparing the kinematic model to observed data of hand movement show the model to be capable of mapping thumb and finger joint flexion angles during grasping motions. Simulations show the exoskeleton to be capable of reproducing the complex motion of the thumb to oppose the fingers during cylindrical and pinch grip motions. © 2011 IEEE

Spectral gamuts and spectral gamut mapping

NASA Astrophysics Data System (ADS)

Rosen, Mitchell R.; Derhak, Maxim W.

2006-01-01

All imaging devices have two gamuts: the stimulus gamut and the response gamut. The response gamut of a print engine is typically described in CIE colorimetry units, a system derived to quantify human color response. More fundamental than colorimetric gamuts are spectral gamuts, based on radiance, reflectance or transmittance units. Spectral gamuts depend on the physics of light or on how materials interact with light and do not involve the human's photoreceptor integration or brain processing. Methods for visualizing a spectral gamut raise challenges as do considerations of how to utilize such a data-set for producing superior color reproductions. Recent work has described a transformation of spectra reduced to 6-dimensions called LabPQR. LabPQR was designed as a hybrid space with three explicit colorimetric axes and three additional spectral reconstruction axes. In this paper spectral gamuts are discussed making use of LabPQR. Also, spectral gamut mapping is considered in light of the colorimetric-spectral duality of the LabPQR space.

Applying manifold learning techniques to the CAESAR database

NASA Astrophysics Data System (ADS)

Mendoza-Schrock, Olga; Patrick, James; Arnold, Gregory; Ferrara, Matthew

2010-04-01

Understanding and organizing data is the first step toward exploiting sensor phenomenology for dismount tracking. What image features are good for distinguishing people and what measurements, or combination of measurements, can be used to classify the dataset by demographics including gender, age, and race? A particular technique, Diffusion Maps, has demonstrated the potential to extract features that intuitively make sense [1]. We want to develop an understanding of this tool by validating existing results on the Civilian American and European Surface Anthropometry Resource (CAESAR) database. This database, provided by the Air Force Research Laboratory (AFRL) Human Effectiveness Directorate and SAE International, is a rich dataset which includes 40 traditional, anthropometric measurements of 4400 human subjects. If we could specifically measure the defining features for classification, from this database, then the future question will then be to determine a subset of these features that can be measured from imagery. This paper briefly describes the Diffusion Map technique, shows potential for dimension reduction of the CAESAR database, and describes interesting problems to be further explored.

Representations of Pitch and Timbre Variation in Human Auditory Cortex

PubMed Central

2017-01-01

Pitch and timbre are two primary dimensions of auditory perception, but how they are represented in the human brain remains a matter of contention. Some animal studies of auditory cortical processing have suggested modular processing, with different brain regions preferentially coding for pitch or timbre, whereas other studies have suggested a distributed code for different attributes across the same population of neurons. This study tested whether variations in pitch and timbre elicit activity in distinct regions of the human temporal lobes. Listeners were presented with sequences of sounds that varied in either fundamental frequency (eliciting changes in pitch) or spectral centroid (eliciting changes in brightness, an important attribute of timbre), with the degree of pitch or timbre variation in each sequence parametrically manipulated. The BOLD responses from auditory cortex increased with increasing sequence variance along each perceptual dimension. The spatial extent, region, and laterality of the cortical regions most responsive to variations in pitch or timbre at the univariate level of analysis were largely overlapping. However, patterns of activation in response to pitch or timbre variations were discriminable in most subjects at an individual level using multivoxel pattern analysis, suggesting a distributed coding of the two dimensions bilaterally in human auditory cortex. SIGNIFICANCE STATEMENT Pitch and timbre are two crucial aspects of auditory perception. Pitch governs our perception of musical melodies and harmonies, and conveys both prosodic and (in tone languages) lexical information in speech. Brightness—an aspect of timbre or sound quality—allows us to distinguish different musical instruments and speech sounds. Frequency-mapping studies have revealed tonotopic organization in primary auditory cortex, but the use of pure tones or noise bands has precluded the possibility of dissociating pitch from brightness. Our results suggest a distributed code, with no clear anatomical distinctions between auditory cortical regions responsive to changes in either pitch or timbre, but also reveal a population code that can differentiate between changes in either dimension within the same cortical regions. PMID:28025255

What colour does that feel? Tactile--visual mapping and the development of cross-modality.

PubMed

Ludwig, Vera U; Simner, Julia

2013-04-01

Humans share implicit preferences for cross-modal mappings (e.g., low pitch sounds are preferentially paired with darker colours). Individuals with synaesthesia experience cross-modal mappings to a conscious degree (e.g., they may see colours when they hear sounds). The neonatal synaesthesia hypothesis claims that all humans may be born with this explicit cross-modal perception, which dies out in most people through childhood, leaving only implicit associations in the average adult. Although there is evidence for decreasing cross-modality throughout early infancy, it is unclear whether this decline continues to take place throughout childhood and adolescence. This large-scale study had two goals. First, we aimed to establish whether human non-synaesthetes systematically map tactile and visual dimensions - a combination that has rarely been studied. Second, we asked whether tactile-visual associations may be more pronounced in younger compared to older participants. 210 participants between the ages of 5-74 years assigned colours to tactile stimuli. Smoothness, softness and roundness of stimuli positively correlated with luminance of the chosen colour; and smoothness and softness also positively correlated with chroma. Moreover, tactile sensations were associated with specific colours (e.g., softness with pink). There were no age differences for luminance effects. Chroma effects, however, were found exclusively in children and adolescents. Our findings are consistent with the neonatal synaesthesia hypothesis which suggests that all humans are born with strong cross-modal perception which is pruned away or inhibited throughout development. Moreover, the findings suggest that a decline of some forms of cross-modality may take place over a much longer time span than previously assumed. Copyright © 2012 Elsevier Ltd. All rights reserved.

A two-dimensional neuropsychology of defense: fear/anxiety and defensive distance.

PubMed

McNaughton, Neil; Corr, Philip J

2004-05-01

We present in this paper a picture of the neural systems controlling defense that updates and simplifies Gray's "Neuropsychology of Anxiety". It is based on two behavioural dimensions: 'defensive distance' as defined by the Blanchards and 'defensive direction'. Defensive direction is a categorical dimension with avoidance of threat corresponding to fear and approach to threat corresponding to anxiety. These two psychological dimensions are mapped to underlying neural dimensions. Defensive distance is mapped to neural level, with the shortest defensive distances involving the lowest neural level (periaqueductal grey) and the largest defensive distances the highest neural level (prefrontal cortex). Defensive direction is mapped to separate parallel streams that run across these levels. A significant departure from prior models is the proposal that both fear and anxiety are represented at all levels. The theory is presented in a simplified form that does not incorporate the interactions that must occur between non-adjacent levels of the system. It also requires expansion to include the dimension of escapability of threat. Our current development and these proposed future extensions do not change the core concepts originally proposed by Gray and, we argue, demonstrate their enduring value.

Ulam method and fractal Weyl law for Perron-Frobenius operators

NASA Astrophysics Data System (ADS)

Ermann, L.; Shepelyansky, D. L.

2010-06-01

We use the Ulam method to study spectral properties of the Perron-Frobenius operators of dynamical maps in a chaotic regime. For maps with absorption we show numerically that the spectrum is characterized by the fractal Weyl law recently established for nonunitary operators describing poles of quantum chaotic scattering with the Weyl exponent ν = d-1, where d is the fractal dimension of corresponding strange set of trajectories nonescaping in future times. In contrast, for dissipative maps we numerically find the Weyl exponent ν = d/2 where d is the fractal dimension of strange attractor. The Weyl exponent can be also expressed via the relation ν = d0/2 where d0 is the fractal dimension of the invariant sets. We also discuss the properties of eigenvalues and eigenvectors of such operators characterized by the fractal Weyl law.

Correlation dimension and phase space contraction via extreme value theory

NASA Astrophysics Data System (ADS)

Faranda, Davide; Vaienti, Sandro

2018-04-01

We show how to obtain theoretical and numerical estimates of correlation dimension and phase space contraction by using the extreme value theory. The maxima of suitable observables sampled along the trajectory of a chaotic dynamical system converge asymptotically to classical extreme value laws where: (i) the inverse of the scale parameter gives the correlation dimension and (ii) the extremal index is associated with the rate of phase space contraction for backward iteration, which in dimension 1 and 2, is closely related to the positive Lyapunov exponent and in higher dimensions is related to the metric entropy. We call it the Dynamical Extremal Index. Numerical estimates are straightforward to obtain as they imply just a simple fit to a univariate distribution. Numerical tests range from low dimensional maps, to generalized Henon maps and climate data. The estimates of the indicators are particularly robust even with relatively short time series.

BOREAS TE-23 Map Plot Data

NASA Technical Reports Server (NTRS)

Rich, Paul M.; Fournier, Robert; Hall, Forrest G. (Editor); Papagno, Andrea (Editor)

2000-01-01

The Boreal Ecosystem-Atmospheric Study (BOREAS) TE-23 (Terrestrial Ecology) team collected map plot data in support of its efforts to characterize and interpret information on canopy architecture and understory cover at the BOREAS tower flux sites and selected auxiliary sites from May to August 1994. Mapped plots (typical dimensions 50 m x 60 m) were set up and characterized at all BOREAS forested tower flux and selected auxiliary sites. Detailed measurement of the mapped plots included: (1) stand characteristics (location, density, basal area); (2) map locations diameter at breast height (DBH) of all trees; (3) detailed geometric measures of a subset of trees (height, crown dimensions); and (4) understory cover maps. The data are stored in tabular ASCII files. The data files are available on a CD-ROM (see document number 20010000884), or from the Oak Ridge National Laboratory (ORNL) Distributed Active Archive Center (DAAC).

A Systematic Review of Mapping Strategies for the Sonification of Physical Quantities

PubMed Central

Dubus, Gaël; Bresin, Roberto

2013-01-01

The field of sonification has progressed greatly over the past twenty years and currently constitutes an established area of research. This article aims at exploiting and organizing the knowledge accumulated in previous experimental studies to build a foundation for future sonification works. A systematic review of these studies may reveal trends in sonification design, and therefore support the development of design guidelines. To this end, we have reviewed and analyzed 179 scientific publications related to sonification of physical quantities. Using a bottom-up approach, we set up a list of conceptual dimensions belonging to both physical and auditory domains. Mappings used in the reviewed works were identified, forming a database of 495 entries. Frequency of use was analyzed among these conceptual dimensions as well as higher-level categories. Results confirm two hypotheses formulated in a preliminary study: pitch is by far the most used auditory dimension in sonification applications, and spatial auditory dimensions are almost exclusively used to sonify kinematic quantities. To detect successful as well as unsuccessful sonification strategies, assessment of mapping efficiency conducted in the reviewed works was considered. Results show that a proper evaluation of sonification mappings is performed only in a marginal proportion of publications. Additional aspects of the publication database were investigated: historical distribution of sonification works is presented, projects are classified according to their primary function, and the sonic material used in the auditory display is discussed. Finally, a mapping-based approach for characterizing sonification is proposed. PMID:24358192

ACCELERATING MR PARAMETER MAPPING USING SPARSITY-PROMOTING REGULARIZATION IN PARAMETRIC DIMENSION

PubMed Central

Velikina, Julia V.; Alexander, Andrew L.; Samsonov, Alexey

2013-01-01

MR parameter mapping requires sampling along additional (parametric) dimension, which often limits its clinical appeal due to a several-fold increase in scan times compared to conventional anatomic imaging. Data undersampling combined with parallel imaging is an attractive way to reduce scan time in such applications. However, inherent SNR penalties of parallel MRI due to noise amplification often limit its utility even at moderate acceleration factors, requiring regularization by prior knowledge. In this work, we propose a novel regularization strategy, which utilizes smoothness of signal evolution in the parametric dimension within compressed sensing framework (p-CS) to provide accurate and precise estimation of parametric maps from undersampled data. The performance of the method was demonstrated with variable flip angle T1 mapping and compared favorably to two representative reconstruction approaches, image space-based total variation regularization and an analytical model-based reconstruction. The proposed p-CS regularization was found to provide efficient suppression of noise amplification and preservation of parameter mapping accuracy without explicit utilization of analytical signal models. The developed method may facilitate acceleration of quantitative MRI techniques that are not suitable to model-based reconstruction because of complex signal models or when signal deviations from the expected analytical model exist. PMID:23213053

Implementation of Fractal Dimension and Self-Organizing Map to Detect Toxic Effects of Toluene on Movement Tracks of Daphnia magna.

PubMed

Liu, Yuedan; Xia, Chunlei; Fan, Zhongya; Wu, Renren; Chen, Xianglin; Liu, Zuoyi

2018-01-01

Movement behaviors of an indicator species, Daphnia magna , in response to contaminants have been implemented to monitor environmental disturbances. Complexity in movement tracks of Daphnia magna was characterized by use of fractal dimension and self-organizing map. The individual movement tracks of D. magna were continuously recorded for 24 hours before and after treatments with toluene at the concentration of 10 mg/L, respectively. The general complexity in movement tracks (10 minutes) was characterized by fractal dimension. Results showed that average fractal dimension of movement tracks was decreased from 1.62 to 1.22 after treatments. The instantaneous movement parameters of movement segments in 5 s were input into the self-organizing map to investigate the swimming pattern changes under stresses of toluene. Abnormal behaviors of D. magna are more frequently observed after treatments than before treatments. Computational methods in ecological informatics could be utilized to obtain the useful information in behavioral data of D. magna and would be further applied as an in situ monitoring tool in water environment.

Using electrical impedance tomography to map subsurface hydraulic conductivity

DOEpatents

Berryman, James G.; Daily, William D.; Ramirez, Abelardo L.; Roberts, Jeffery J.

2000-01-01

The use of Electrical Impedance Tomography (EIT) to map subsurface hydraulic conductivity. EIT can be used to map hydraulic conductivity in the subsurface where measurements of both amplitude and phase are made. Hydraulic conductivity depends on at least two parameters: porosity and a length scale parameter. Electrical Resistance Tomography (ERT) measures and maps electrical conductivity (which can be related to porosity) in three dimensions. By introducing phase measurements along with amplitude, the desired additional measurement of a pertinent length scale can be achieved. Hydraulic conductivity controls the ability to flush unwanted fluid contaminants from the surface. Thus inexpensive maps of hydraulic conductivity would improve planning strategies for subsequent remediation efforts. Fluid permeability is also of importance for oil field exploitation and thus detailed knowledge of fluid permeability distribution in three-dimension (3-D) would be a great boon to petroleum reservoir analysts.

Selecting landscape metrics as indicators of spatial heterogeneity-A comparison among Greek landscapes

NASA Astrophysics Data System (ADS)

Plexida, Sofia G.; Sfougaris, Athanassios I.; Ispikoudis, Ioannis P.; Papanastasis, Vasilios P.

2014-02-01

This paper investigates the spatial heterogeneity of three landscapes along an altitudinal gradient and different human land use. The main aim was the identification of appropriate landscape indicators using different extents. ASTER image was used to create a land cover map consisting of three landscapes which differed in altitude and land use. A number of landscape metrics quantifying patch complexity, configuration, diversity and connectivity were derived from the thematic map at the landscape level. There were significant differences among the three landscapes regarding these four aspects of landscape heterogeneity. The analysis revealed a specific pattern of land use where lowlands are being increasingly utilized by humans (percentage of agricultural land = 65.84%) characterized by physical connectedness (high values of Patch Cohesion Index) and relatively simple geometries (low values of fractal dimension index). The landscape pattern of uplands was found to be highly diverse based upon the Shannon Diversity index. After selecting the scale (600 ha) where metrics values stabilized, it was shown that metrics were more correlated at the small scale of 60 ha. From the original 24 metrics, 14 individual metrics with high Spearman correlation coefficient and Variance Inflation Factor criterion were eliminated, leaving 10 representative metrics for subsequent analysis. Data reduction analysis showed that Patch Density, Area-Weighted Mean Fractal Dimension Index and Patch Cohesion Index are suitable to describe landscape patterns irrespective of the scale. A systematic screening of these metrics could enhance a deeper understanding of the results obtained by them and contribute to a sustainable landscape management of Mediterranean landscapes.

Length and area equivalents for interpreting wildland resource maps

Treesearch

Elliot L. Amidon; Marilyn S. Whitfield

1969-01-01

Map users must refer to an appropriate scale in interpreting wildland resource maps. Length and area equivalents for nine map scales commonly used have been computed. For each scale a 1-page table consists of map-to-ground equivalents, buffer strip or road widths, and cell dimensions required for a specified acreage. The conversion factors are stored in a Fortran...

Diffusion maps for high-dimensional single-cell analysis of differentiation data.

PubMed

Haghverdi, Laleh; Buettner, Florian; Theis, Fabian J

2015-09-15

Single-cell technologies have recently gained popularity in cellular differentiation studies regarding their ability to resolve potential heterogeneities in cell populations. Analyzing such high-dimensional single-cell data has its own statistical and computational challenges. Popular multivariate approaches are based on data normalization, followed by dimension reduction and clustering to identify subgroups. However, in the case of cellular differentiation, we would not expect clear clusters to be present but instead expect the cells to follow continuous branching lineages. Here, we propose the use of diffusion maps to deal with the problem of defining differentiation trajectories. We adapt this method to single-cell data by adequate choice of kernel width and inclusion of uncertainties or missing measurement values, which enables the establishment of a pseudotemporal ordering of single cells in a high-dimensional gene expression space. We expect this output to reflect cell differentiation trajectories, where the data originates from intrinsic diffusion-like dynamics. Starting from a pluripotent stage, cells move smoothly within the transcriptional landscape towards more differentiated states with some stochasticity along their path. We demonstrate the robustness of our method with respect to extrinsic noise (e.g. measurement noise) and sampling density heterogeneities on simulated toy data as well as two single-cell quantitative polymerase chain reaction datasets (i.e. mouse haematopoietic stem cells and mouse embryonic stem cells) and an RNA-Seq data of human pre-implantation embryos. We show that diffusion maps perform considerably better than Principal Component Analysis and are advantageous over other techniques for non-linear dimension reduction such as t-distributed Stochastic Neighbour Embedding for preserving the global structures and pseudotemporal ordering of cells. The Matlab implementation of diffusion maps for single-cell data is available at https://www.helmholtz-muenchen.de/icb/single-cell-diffusion-map. fbuettner.phys@gmail.com, fabian.theis@helmholtz-muenchen.de Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Local connectome phenotypes predict social, health, and cognitive factors

PubMed Central

Powell, Michael A.; Garcia, Javier O.; Yeh, Fang-Cheng; Vettel, Jean M.

2018-01-01

The unique architecture of the human connectome is defined initially by genetics and subsequently sculpted over time with experience. Thus, similarities in predisposition and experience that lead to similarities in social, biological, and cognitive attributes should also be reflected in the local architecture of white matter fascicles. Here we employ a method known as local connectome fingerprinting that uses diffusion MRI to measure the fiber-wise characteristics of macroscopic white matter pathways throughout the brain. This fingerprinting approach was applied to a large sample (N = 841) of subjects from the Human Connectome Project, revealing a reliable degree of between-subject correlation in the local connectome fingerprints, with a relatively complex, low-dimensional substructure. Using a cross-validated, high-dimensional regression analysis approach, we derived local connectome phenotype (LCP) maps that could reliably predict a subset of subject attributes measured, including demographic, health, and cognitive measures. These LCP maps were highly specific to the attribute being predicted but also sensitive to correlations between attributes. Collectively, these results indicate that the local architecture of white matter fascicles reflects a meaningful portion of the variability shared between subjects along several dimensions. PMID:29911679

Local connectome phenotypes predict social, health, and cognitive factors.

PubMed

Powell, Michael A; Garcia, Javier O; Yeh, Fang-Cheng; Vettel, Jean M; Verstynen, Timothy

2018-01-01

The unique architecture of the human connectome is defined initially by genetics and subsequently sculpted over time with experience. Thus, similarities in predisposition and experience that lead to similarities in social, biological, and cognitive attributes should also be reflected in the local architecture of white matter fascicles. Here we employ a method known as local connectome fingerprinting that uses diffusion MRI to measure the fiber-wise characteristics of macroscopic white matter pathways throughout the brain. This fingerprinting approach was applied to a large sample ( N = 841) of subjects from the Human Connectome Project, revealing a reliable degree of between-subject correlation in the local connectome fingerprints, with a relatively complex, low-dimensional substructure. Using a cross-validated, high-dimensional regression analysis approach, we derived local connectome phenotype (LCP) maps that could reliably predict a subset of subject attributes measured, including demographic, health, and cognitive measures. These LCP maps were highly specific to the attribute being predicted but also sensitive to correlations between attributes. Collectively, these results indicate that the local architecture of white matter fascicles reflects a meaningful portion of the variability shared between subjects along several dimensions.

Investigating the U.S. Army’s Human Dimension Strategy

DTIC Science & Technology

2016-06-01

1 Investigating the U.S. Army’s Human Dimension Strategy By Steven C. Song Bachelor of Science in Engineering Management...3 Investigating the U.S. Army’s Human Dimension Strategy by Steven C. Song Submitted to the...Management Abstract In 2015, the U.S. Army developed a vision to “win in a complex world” called the Army Human Dimension Strategy (AHDS). The

Underlying mathematics in diversification of human olfactory receptors in different loci.

PubMed

Hassan, Sk Sarif; Choudhury, Pabitra Pal; Goswami, Arunava

2013-12-01

As per conservative estimate, approximately 51-105 Olfactory Receptors (ORs) loci are present in human genome occurring in clusters. These clusters are apparently unevenly spread as mosaics over 21 pairs of human chromosomes. Olfactory Receptor (OR) gene families which are thought to have expanded for the need to provide recognition capability for a huge number of pure and complex odorants, form the largest known multigene family in the human genome. Recent studies have shown that 388 full length and 414 OR pseudo-genes are present in these OR genomic clusters. In this paper, the authors report a classification method for all human ORs based on their sequential quantitative information like presence of poly strings of nucleotides bases, long range correlation and so on. An L-System generated sequence has been taken as an input into a star-model of specific subfamily members and resultant sequence has been mapped to a specific OR based on the classification scheme using fractal parameters like Hurst exponent and fractal dimensions.

New dimensions from statistical graphics for GIS (geographic information system) analysis and interpretation

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCord, R.A.; Olson, R.J.

1988-01-01

Environmental research and assessment activities at Oak Ridge National Laboratory (ORNL) include the analysis of spatial and temporal patterns of ecosystem response at a landscape scale. Analysis through use of geographic information system (GIS) involves an interaction between the user and thematic data sets frequently expressed as maps. A portion of GIS analysis has a mathematical or statistical aspect, especially for the analysis of temporal patterns. ARC/INFO is an excellent tool for manipulating GIS data and producing the appropriate map graphics. INFO also has some limited ability to produce statistical tabulation. At ORNL we have extended our capabilities by graphicallymore » interfacing ARC/INFO and SAS/GRAPH to provide a combined mapping and statistical graphics environment. With the data management, statistical, and graphics capabilities of SAS added to ARC/INFO, we have expanded the analytical and graphical dimensions of the GIS environment. Pie or bar charts, frequency curves, hydrographs, or scatter plots as produced by SAS can be added to maps from attribute data associated with ARC/INFO coverages. Numerous, small, simplified graphs can also become a source of complex map ''symbols.'' These additions extend the dimensions of GIS graphics to include time, details of the thematic composition, distribution, and interrelationships. 7 refs., 3 figs.« less

Multiple regression based imputation for individualizing template human model from a small number of measured dimensions.

PubMed

Nohara, Ryuki; Endo, Yui; Murai, Akihiko; Takemura, Hiroshi; Kouchi, Makiko; Tada, Mitsunori

2016-08-01

Individual human models are usually created by direct 3D scanning or deforming a template model according to the measured dimensions. In this paper, we propose a method to estimate all the necessary dimensions (full set) for the human model individualization from a small number of measured dimensions (subset) and human dimension database. For this purpose, we solved multiple regression equation from the dimension database given full set dimensions as the objective variable and subset dimensions as the explanatory variables. Thus, the full set dimensions are obtained by simply multiplying the subset dimensions to the coefficient matrix of the regression equation. We verified the accuracy of our method by imputing hand, foot, and whole body dimensions from their dimension database. The leave-one-out cross validation is employed in this evaluation. The mean absolute errors (MAE) between the measured and the estimated dimensions computed from 4 dimensions (hand length, breadth, middle finger breadth at proximal, and middle finger depth at proximal) in the hand, 2 dimensions (foot length, breadth, and lateral malleolus height) in the foot, and 1 dimension (height) and weight in the whole body are computed. The average MAE of non-measured dimensions were 4.58% in the hand, 4.42% in the foot, and 3.54% in the whole body, while that of measured dimensions were 0.00%.

Changing the personality of a face: Perceived Big Two and Big Five personality factors modeled in real photographs.

PubMed

Walker, Mirella; Vetter, Thomas

2016-04-01

General, spontaneous evaluations of strangers based on their faces have been shown to reflect judgments of these persons' intention and ability to harm. These evaluations can be mapped onto a 2D space defined by the dimensions trustworthiness (intention) and dominance (ability). Here we go beyond general evaluations and focus on more specific personality judgments derived from the Big Two and Big Five personality concepts. In particular, we investigate whether Big Two/Big Five personality judgments can be mapped onto the 2D space defined by the dimensions trustworthiness and dominance. Results indicate that judgments of the Big Two personality dimensions almost perfectly map onto the 2D space. In contrast, at least 3 of the Big Five dimensions (i.e., neuroticism, extraversion, and conscientiousness) go beyond the 2D space, indicating that additional dimensions are necessary to describe more specific face-based personality judgments accurately. Building on this evidence, we model the Big Two/Big Five personality dimensions in real facial photographs. Results from 2 validation studies show that the Big Two/Big Five are perceived reliably across different samples of faces and participants. Moreover, results reveal that participants differentiate reliably between the different Big Two/Big Five dimensions. Importantly, this high level of agreement and differentiation in personality judgments from faces likely creates a subjective reality which may have serious consequences for those being perceived-notably, these consequences ensue because the subjective reality is socially shared, irrespective of the judgments' validity. The methodological approach introduced here might prove useful in various psychological disciplines. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Transitive Relational Mappings in Three- and Four-Year-Olds: The Analogy of Goldilocks and the Three Bears.

ERIC Educational Resources Information Center

Goswami, Usha

1995-01-01

In three experiments, three- and four-year olds were asked to map relative size from one array of objects to another, map relative size to relative proportion, and map relative size to a variety of perceptual dimensions. Children were able to make relational mappings based on size when spatial positions and concrete representations of size of…

Fast-dynamo action in unsteady flows and maps in three dimensions

NASA Technical Reports Server (NTRS)

Bayly, B. J.; Childress, S.

1987-01-01

Unsteady fast-dynamo action is obtained in a family of stretch-fold-shear maps applied to a spatially periodic magnetic field in three dimensions. Exponential growth of a mean field in the limit of vanishing diffusivity is demonstrated by a numerical method which alternates instantaneous deformations with molecular diffusion over a finite time interval. Analysis indicates that the dynamo is a coherent feature of the large scales, essentially independent of the cascade of structure to small scales.

3D FISH to analyse gene domain-specific chromatin re-modeling in human cancer cell lines.

PubMed

Kocanova, Silvia; Goiffon, Isabelle; Bystricky, Kerstin

2018-06-01

Fluorescence in situ hybridization (FISH) is a common technique used to label DNA and/or RNA for detection of a genomic region of interest. However, the technique can be challenging, in particular when applied to single genes in human cancer cells. Here, we provide a step-by-step protocol for analysis of short (35 kb-300 kb) genomic regions in three dimensions (3D). We discuss the experimental design and provide practical considerations for 3D imaging and data analysis to determine chromatin folding. We demonstrate that 3D FISH using BACs (Bacterial Artificial Chromosomes) or fosmids can provide detailed information of the architecture of gene domains. More specifically, we show that mapping of specific chromatin landscapes informs on changes associated with estrogen stimulated gene activity in human breast cancer cell lines. Copyright © 2018 Elsevier Inc. All rights reserved.

How Deep Is Your SNARC? Interactions Between Numerical Magnitude, Response Hands, and Reachability in Peripersonal Space.

PubMed

Lohmann, Johannes; Schroeder, Philipp A; Nuerk, Hans-Christoph; Plewnia, Christian; Butz, Martin V

2018-01-01

Spatial, physical, and semantic magnitude dimensions can influence action decisions in human cognitive processing and interact with each other. For example, in the spatial-numerical associations of response code (SNARC) effect, semantic numerical magnitude facilitates left-hand or right-hand responding dependent on the small or large magnitude of number symbols. SNARC-like interactions of numerical magnitudes with the radial spatial dimension (depth) were postulated from early on. Usually, the SNARC effect in any direction is investigated using fronto-parallel computer monitors for presentation of stimuli. In such 2D setups, however, the metaphorical and literal interpretation of the radial depth axis with seemingly close/far stimuli or responses are not distinct. Hence, it is difficult to draw clear conclusions with respect to the contribution of different spatial mappings to the SNARC effect. In order to disentangle the different mappings in a natural way, we studied parametrical interactions between semantic numerical magnitude, horizontal directional responses, and perceptual distance by means of stereoscopic depth in an immersive virtual reality (VR). Two VR experiments show horizontal SNARC effects across all spatial displacements in traditional latency measures and kinematic response parameters. No indications of a SNARC effect along the depth axis, as it would be predicted by a direct mapping account, were observed, but the results show a non-linear relationship between horizontal SNARC slopes and physical distance. Steepest SNARC slopes were observed for digits presented close to the hands. We conclude that spatial-numerical processing is susceptible to effector-based processes but relatively resilient to task-irrelevant variations of radial-spatial magnitudes.

Organizational readiness for knowledge translation in chronic care: a Delphi study.

PubMed

Attieh, Randa; Gagnon, Marie-Pierre; Estabrooks, Carole A; Légaré, France; Ouimet, Mathieu; Vazquez, Patricia; Nuño, Roberto

2014-11-08

Health-care organizations need to be ready prior to implement evidence-based interventions. In this study, we sought to achieve consensus on a framework to assess the readiness of health-care organizations to implement evidence-based interventions in the context of chronic care. We conducted a web-based modified Delphi study between March and May 2013. We contacted 76 potentially eligible international experts working in the fields of organizational readiness (OR), knowledge translation (KT), and chronic care to comment upon the 76 elements resulting from our proposed conceptual map. This conceptual map was based on a systematic review of the existing frameworks of Organizational Readiness for Change (ORC) in health-care. We developed a conceptual map that proposed a set of core concepts and their associated 17 dimensions and 59 sub-dimensions. Experts rated their agreement concerning the applicability and importance of ORC elements on a 5-point Likert scale, where 1 indicates total disagreement and 5 indicates total agreement. Two rounds were needed to get a consensus from the experts. Consensus was a priori defined as strong (≥75%) or moderate (60-74%). Simple descriptive statistics was used. In total, 14 participants completed the first round and 10 completed the two rounds. Panel members reached consensus on the applicability and importance of 6 out of 17 dimensions and 28 out of 59 sub-dimensions to assess OR for KT in the context of chronic care. A strong level of consensus (≥75%) was attained on the Organizational contextual factors, Leadership/participation, Organizational support, and Motivation dimensions. The Organizational climate for change and Change content dimensions reached a moderate consensus (60-74%). Experts also reached consensus on 28 out of 59 sub-dimensions to assess OR for KT. Twenty-one sub-dimensions reached a strong consensus (≥75%) and seven a moderate consensus (60-74%). This study results provided the most important and applicable dimensions and sub-dimensions for assessing OR-KT in the context of chronic care. They can be used to guide the design of an assessment tool to improve knowledge translation in the field of chronic care.

The Specificity of Sound Symbolic Correspondences in Spoken Language.

PubMed

Tzeng, Christina Y; Nygaard, Lynne C; Namy, Laura L

2017-11-01

Although language has long been regarded as a primarily arbitrary system, sound symbolism, or non-arbitrary correspondences between the sound of a word and its meaning, also exists in natural language. Previous research suggests that listeners are sensitive to sound symbolism. However, little is known about the specificity of these mappings. This study investigated whether sound symbolic properties correspond to specific meanings, or whether these properties generalize across semantic dimensions. In three experiments, native English-speaking adults heard sound symbolic foreign words for dimensional adjective pairs (big/small, round/pointy, fast/slow, moving/still) and for each foreign word, selected a translation among English antonyms that either matched or mismatched with the correct meaning dimension. Listeners agreed more reliably on the English translation for matched relative to mismatched dimensions, though reliable cross-dimensional mappings did occur. These findings suggest that although sound symbolic properties generalize to meanings that may share overlapping semantic features, sound symbolic mappings offer semantic specificity. Copyright © 2016 Cognitive Science Society, Inc.

Ocean Thermal Feature Recognition, Discrimination and Tracking Using Infrared Satellite Imagery

DTIC Science & Technology

1991-06-01

rejected if the temperature in the mapped area exceeds classification criteria ............................... 17 viii 2.6 Ideal feature space mapping from...in seconds, and 1P is the side dimension of the pixel in meters. Figure 2.6: Ideal feature space mapping from pattern tile - search tile comparison. 20

Relations of Central Hemodynamics and Aortic Stiffness with Left Ventricular Structure and Function: The Framingham Heart Study.

PubMed

Kaess, Bernhard M; Rong, Jian; Larson, Martin G; Hamburg, Naomi M; Vita, Joseph A; Cheng, Susan; Aragam, Jayashree; Levy, Daniel; Benjamin, Emelia J; Vasan, Ramachandran S; Mitchell, Gary F

2016-03-25

The differing relations of steady and pulsatile components of central hemodynamics and aortic stiffness with cardiac dimensions and function have not been fully elucidated. Central hemodynamics and carotid-femoral pulse wave velocity (CFPWV, a measure of aortic stiffness) were measured by arterial tonometry in 5799 participants of the Framingham Heart Study (mean age 51 years, 54% women) and related to echocardiographic left ventricular (LV) dimensions and systolic and diastolic function using multivariable-adjusted partial Pearson correlations. Mean arterial pressure (MAP, steady component of central blood pressure) was associated positively with LV wall thickness (r=0.168; P<0.0001) but showed only a weak direct association with LV diastolic dimension (r=0.035, P=0.006). Central pulse pressure (pulsatile component of central blood pressure) showed a direct correlation with both LV diastolic dimension and LV wall thickness (r=0.08 and 0.044, both P<0.0001 in multivariable models that included MAP). CFPWV was not associated with LV structure (all P≥0.27) in MAP-adjusted models). Both MAP and CFPWV were associated inversely with LV diastolic function (E'; r=-0.140 and -0.153, respectively; both P<0.0001), and these associations persisted after additional adjustment for LV mass and central pulse pressure (r=-0.142 and -0.108, both P<0.0001). MAP and CFPWV were not associated with LV fractional shortening (P≥0.10), whereas central pulse pressure was positively related (r=0.064, P<0.0001). Pulsatile and steady components of central pressure are conjointly yet variably related to LV structure. CFPWV is related to LV diastolic function but not to systolic function. Additional studies are warranted to confirm these observations. © 2016 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

Some effects of acceleration in man and chimpanzees. [gravitational effects

NASA Technical Reports Server (NTRS)

Wood, E. H.; Sass, D. J.; Ritman, E. L.; Greenleaf, J. F.; Coulam, C. M.; Nathan, D.; Nolan, E. C.

1977-01-01

Early physiologic experiments using dogs and humans in centrifuges are reviewed. Because of the close similarity between the shape and dimensions of the thoraces of chimpanzees and humans, the former were used to obtain roentgenograms and photokymographic recordings of multiple physiologic variables before and during exposure to +5.8 Gy to study the effects of changes in the gravitational-inertial force environment on the cardiovascular and pulmonary systems during long duration space flight. A computer-controlled sciscanning system was used to obtain a two dimensional map of the amount of radiation emanating from the dorsal and ventricle surfaces after insertion of radioactive microspheres in the right ventricle. By using four different batches of microspheres tagged with isotopes of different energies, the spatial distribution of pulmonary blood flow under four conditions was determined.

2.5D multi-view gait recognition based on point cloud registration.

PubMed

Tang, Jin; Luo, Jian; Tjahjadi, Tardi; Gao, Yan

2014-03-28

This paper presents a method for modeling a 2.5-dimensional (2.5D) human body and extracting the gait features for identifying the human subject. To achieve view-invariant gait recognition, a multi-view synthesizing method based on point cloud registration (MVSM) to generate multi-view training galleries is proposed. The concept of a density and curvature-based Color Gait Curvature Image is introduced to map 2.5D data onto a 2D space to enable data dimension reduction by discrete cosine transform and 2D principle component analysis. Gait recognition is achieved via a 2.5D view-invariant gait recognition method based on point cloud registration. Experimental results on the in-house database captured by a Microsoft Kinect camera show a significant performance gain when using MVSM.

Geochemical surveys in the United States in relation to health.

USGS Publications Warehouse

Tourtelot, H.A.

1979-01-01

Geochemical surveys in relation to health may be classified as having one, two or three dimensions. One-dimensional surveys examine relations between concentrations of elements such as Pb in soils and other media and burdens of the same elements in humans, at a given time. The spatial distributions of element concentrations are not investigated. The primary objective of two-dimensional surveys is to map the distributions of element concentrations, commonly according to stratified random sampling designs based on either conceptual landscape units or artificial sampling strata, but systematic sampling intervals have also been used. Political units have defined sample areas that coincide with the units used to accumulate epidemiological data. Element concentrations affected by point sources have also been mapped. Background values, location of natural or technological anomalies and the geographic scale of variation for several elements often are determined. Three-dimensional surveys result when two-dimensional surveys are repeated to detect environmental changes. -Author

Functional feature embedded space mapping of fMRI data.

PubMed

Hu, Jin; Tian, Jie; Yang, Lei

2006-01-01

We have proposed a new method for fMRI data analysis which is called Functional Feature Embedded Space Mapping (FFESM). Our work mainly focuses on the experimental design with periodic stimuli which can be described by a number of Fourier coefficients in the frequency domain. A nonlinear dimension reduction technique Isomap is applied to the high dimensional features obtained from frequency domain of the fMRI data for the first time. Finally, the presence of activated time series is identified by the clustering method in which the information theoretic criterion of minimum description length (MDL) is used to estimate the number of clusters. The feasibility of our algorithm is demonstrated by real human experiments. Although we focus on analyzing periodic fMRI data, the approach can be extended to analyze non-periodic fMRI data (event-related fMRI) by replacing the Fourier analysis with a wavelet analysis.

Resonance Raman imaging for detecting and monitoring molecular pathological changes in human brain tumors related to Warburg effect

NASA Astrophysics Data System (ADS)

Zhou, Yan; Liu, Cheng-hui; Zhu, Ke; Zhang, Chunyuan; Yang, Yang; Yu, Xinguang; Hu, Hailong; Cheng, Gangge; Wu, Binlin; Shi, Lingyan; Alfano, Robert R.

2018-02-01

The goal of the research is to determine the prognostic molecular pathological changes in components and composition, for human brain glioma gradings in comparison with normal tissues in three-dimensional Raman imaging profiles by visible Resonance Raman (VRR) imaging. VRR images from twenty-five specimens including three healthy tissues, one normal control, and twenty-one glioma tissues of grades II, II-III and III-IV with histology examination were measured and investigated using WITec300R confocal micro Raman imaging system with laser excitation of 532nm. Two-dimensional RR spectral mappings performed in 20μm x 20μm generated 400 images which integrated the intensity of the specific biochemical bonds as the third dimension. The three-dimension (3D) map demonstrated the spatial distributions of three selected sets of RR spectra of molecular biomarkers, and revealed significant differences in the spectra between normal and glioma tissues of different grades due to the composition changes in key molimageecules. These RR molecular spectral fingerprints have displayed: a clear enhancement of RR vibrational modes at 1129-1131cm-1 and 2934cm-1 which are supposed to be arising from lipoproteins; evident decreased RR vibrational modes at 1442cm-1 and 2854cm-1 which are from saturated fatty acids bonds in all-grades of glioma brain tissues compared with normal tissues; and the enhanced RR spectral modes of 1129 cm-1 and 2938cm-1 which suggest contribution from lactate. These findings may provide a novel proof for anaerobic glycolysis metabolic process in brain glioma cancer tissues that has been explained by Warburg effects.

Feature integration theory revisited: dissociating feature detection and attentional guidance in visual search.

PubMed

Chan, Louis K H; Hayward, William G

2009-02-01

In feature integration theory (FIT; A. Treisman & S. Sato, 1990), feature detection is driven by independent dimensional modules, and other searches are driven by a master map of locations that integrates dimensional information into salience signals. Although recent theoretical models have largely abandoned this distinction, some observed results are difficult to explain in its absence. The present study measured dimension-specific performance during detection and localization, tasks that require operation of dimensional modules and the master map, respectively. Results showed a dissociation between tasks in terms of both dimension-switching costs and cross-dimension attentional capture, reflecting a dimension-specific nature for detection tasks and a dimension-general nature for localization tasks. In a feature-discrimination task, results precluded an explanation based on response mode. These results are interpreted to support FIT's postulation that different mechanisms are involved in parallel and focal attention searches. This indicates that the FIT architecture should be adopted to explain the current results and that a variety of visual attention findings can be addressed within this framework. Copyright 2009 APA, all rights reserved.

Towards early detection of cervical cancer: Fractal dimension of AFM images of human cervical epithelial cells at different stages of progression to cancer.

PubMed

Guz, Nataliia V; Dokukin, Maxim E; Woodworth, Craig D; Cardin, Andrew; Sokolov, Igor

2015-10-01

We used AFM HarmoniX modality to analyse the surface of individual human cervical epithelial cells at three stages of progression to cancer, normal, immortal (pre-malignant) and carcinoma cells. Primary cells from 6 normal strains, 6 cancer, and 6 immortalized lines (derived by plasmid DNA-HPV-16 transfection of cells from 6 healthy individuals) were tested. This cell model allowed for good control of the cell phenotype down to the single cell level, which is impractical to attain in clinical screening tests (ex-vivo). AFM maps of physical (nonspecific) adhesion are collected on fixed dried cells. We show that a surface parameter called fractal dimension can be used to segregate normal from both immortal pre-malignant and malignant cells with sensitivity and specificity of more than 99%. The reported method of analysis can be directly applied to cells collected in liquid cytology screening tests and identified as abnormal with regular optical methods to increase sensitivity. Despite cervical smear screening, sometimes it is very difficult to differentiate cancers cells from pre-malignant cells. By using AFM to analyze the surface properties of human cervical epithelial cells, the authors were able to accurately identify normal from abnormal cells. This method could augment existing protocols to increase diagnostic accuracy. Copyright © 2015. Published by Elsevier Inc.

A simple genetic architecture underlies morphological variation in dogs.

PubMed

Boyko, Adam R; Quignon, Pascale; Li, Lin; Schoenebeck, Jeffrey J; Degenhardt, Jeremiah D; Lohmueller, Kirk E; Zhao, Keyan; Brisbin, Abra; Parker, Heidi G; vonHoldt, Bridgett M; Cargill, Michele; Auton, Adam; Reynolds, Andy; Elkahloun, Abdel G; Castelhano, Marta; Mosher, Dana S; Sutter, Nathan B; Johnson, Gary S; Novembre, John; Hubisz, Melissa J; Siepel, Adam; Wayne, Robert K; Bustamante, Carlos D; Ostrander, Elaine A

2010-08-10

Domestic dogs exhibit tremendous phenotypic diversity, including a greater variation in body size than any other terrestrial mammal. Here, we generate a high density map of canine genetic variation by genotyping 915 dogs from 80 domestic dog breeds, 83 wild canids, and 10 outbred African shelter dogs across 60,968 single-nucleotide polymorphisms (SNPs). Coupling this genomic resource with external measurements from breed standards and individuals as well as skeletal measurements from museum specimens, we identify 51 regions of the dog genome associated with phenotypic variation among breeds in 57 traits. The complex traits include average breed body size and external body dimensions and cranial, dental, and long bone shape and size with and without allometric scaling. In contrast to the results from association mapping of quantitative traits in humans and domesticated plants, we find that across dog breeds, a small number of quantitative trait loci (< or = 3) explain the majority of phenotypic variation for most of the traits we studied. In addition, many genomic regions show signatures of recent selection, with most of the highly differentiated regions being associated with breed-defining traits such as body size, coat characteristics, and ear floppiness. Our results demonstrate the efficacy of mapping multiple traits in the domestic dog using a database of genotyped individuals and highlight the important role human-directed selection has played in altering the genetic architecture of key traits in this important species.

A Simple Genetic Architecture Underlies Morphological Variation in Dogs

PubMed Central

Schoenebeck, Jeffrey J.; Degenhardt, Jeremiah D.; Lohmueller, Kirk E.; Zhao, Keyan; Brisbin, Abra; Parker, Heidi G.; vonHoldt, Bridgett M.; Cargill, Michele; Auton, Adam; Reynolds, Andy; Elkahloun, Abdel G.; Castelhano, Marta; Mosher, Dana S.; Sutter, Nathan B.; Johnson, Gary S.; Novembre, John; Hubisz, Melissa J.; Siepel, Adam; Wayne, Robert K.; Bustamante, Carlos D.; Ostrander, Elaine A.

2010-01-01

Domestic dogs exhibit tremendous phenotypic diversity, including a greater variation in body size than any other terrestrial mammal. Here, we generate a high density map of canine genetic variation by genotyping 915 dogs from 80 domestic dog breeds, 83 wild canids, and 10 outbred African shelter dogs across 60,968 single-nucleotide polymorphisms (SNPs). Coupling this genomic resource with external measurements from breed standards and individuals as well as skeletal measurements from museum specimens, we identify 51 regions of the dog genome associated with phenotypic variation among breeds in 57 traits. The complex traits include average breed body size and external body dimensions and cranial, dental, and long bone shape and size with and without allometric scaling. In contrast to the results from association mapping of quantitative traits in humans and domesticated plants, we find that across dog breeds, a small number of quantitative trait loci (≤3) explain the majority of phenotypic variation for most of the traits we studied. In addition, many genomic regions show signatures of recent selection, with most of the highly differentiated regions being associated with breed-defining traits such as body size, coat characteristics, and ear floppiness. Our results demonstrate the efficacy of mapping multiple traits in the domestic dog using a database of genotyped individuals and highlight the important role human-directed selection has played in altering the genetic architecture of key traits in this important species. PMID:20711490

X-ray fluorescence microscopy artefacts in elemental maps of topologically complex samples: Analytical observations, simulation and a map correction method

NASA Astrophysics Data System (ADS)

Billè, Fulvio; Kourousias, George; Luchinat, Enrico; Kiskinova, Maya; Gianoncelli, Alessandra

2016-08-01

XRF spectroscopy is among the most widely used non-destructive techniques for elemental analysis. Despite the known angular dependence of X-ray fluorescence (XRF), topological artefacts remain an unresolved issue when using X-ray micro- or nano-probes. In this work we investigate the origin of the artefacts in XRF imaging of topologically complex samples, which are unresolved problems in studies of organic matter due to the limited travel distances of low energy XRF emission from the light elements. In particular we mapped Human Embryonic Kidney (HEK293T) cells. The exemplary results with biological samples, obtained with a soft X-ray scanning microscope installed at a synchrotron facility were used for testing a mathematical model based on detector response simulations, and for proposing an artefact correction method based on directional derivatives. Despite the peculiar and specific application, the methodology can be easily extended to hard X-rays and to set-ups with multi-array detector systems when the dimensions of surface reliefs are in the order of the probing beam size.

Neural Network Machine Learning and Dimension Reduction for Data Visualization

NASA Technical Reports Server (NTRS)

Liles, Charles A.

2014-01-01

Neural network machine learning in computer science is a continuously developing field of study. Although neural network models have been developed which can accurately predict a numeric value or nominal classification, a general purpose method for constructing neural network architecture has yet to be developed. Computer scientists are often forced to rely on a trial-and-error process of developing and improving accurate neural network models. In many cases, models are constructed from a large number of input parameters. Understanding which input parameters have the greatest impact on the prediction of the model is often difficult to surmise, especially when the number of input variables is very high. This challenge is often labeled the "curse of dimensionality" in scientific fields. However, techniques exist for reducing the dimensionality of problems to just two dimensions. Once a problem's dimensions have been mapped to two dimensions, it can be easily plotted and understood by humans. The ability to visualize a multi-dimensional dataset can provide a means of identifying which input variables have the highest effect on determining a nominal or numeric output. Identifying these variables can provide a better means of training neural network models; models can be more easily and quickly trained using only input variables which appear to affect the outcome variable. The purpose of this project is to explore varying means of training neural networks and to utilize dimensional reduction for visualizing and understanding complex datasets.

Common spatial pattern combined with kernel linear discriminate and generalized radial basis function for motor imagery-based brain computer interface applications

NASA Astrophysics Data System (ADS)

Hekmatmanesh, Amin; Jamaloo, Fatemeh; Wu, Huapeng; Handroos, Heikki; Kilpeläinen, Asko

2018-04-01

Brain Computer Interface (BCI) can be a challenge for developing of robotic, prosthesis and human-controlled systems. This work focuses on the implementation of a common spatial pattern (CSP) base algorithm to detect event related desynchronization patterns. Utilizing famous previous work in this area, features are extracted by filter bank with common spatial pattern (FBCSP) method, and then weighted by a sensitive learning vector quantization (SLVQ) algorithm. In the current work, application of the radial basis function (RBF) as a mapping kernel of linear discriminant analysis (KLDA) method on the weighted features, allows the transfer of data into a higher dimension for more discriminated data scattering by RBF kernel. Afterwards, support vector machine (SVM) with generalized radial basis function (GRBF) kernel is employed to improve the efficiency and robustness of the classification. Averagely, 89.60% accuracy and 74.19% robustness are achieved. BCI Competition III, Iva data set is used to evaluate the algorithm for detecting right hand and foot imagery movement patterns. Results show that combination of KLDA with SVM-GRBF classifier makes 8.9% and 14.19% improvements in accuracy and robustness, respectively. For all the subjects, it is concluded that mapping the CSP features into a higher dimension by RBF and utilization GRBF as a kernel of SVM, improve the accuracy and reliability of the proposed method.

magHD: a new approach to multi-dimensional data storage, analysis, display and exploitation

NASA Astrophysics Data System (ADS)

Angleraud, Christophe

2014-06-01

The ever increasing amount of data and processing capabilities - following the well- known Moore's law - is challenging the way scientists and engineers are currently exploiting large datasets. The scientific visualization tools, although quite powerful, are often too generic and provide abstract views of phenomena, thus preventing cross disciplines fertilization. On the other end, Geographic information Systems allow nice and visually appealing maps to be built but they often get very confused as more layers are added. Moreover, the introduction of time as a fourth analysis dimension to allow analysis of time dependent phenomena such as meteorological or climate models, is encouraging real-time data exploration techniques that allow spatial-temporal points of interests to be detected by integration of moving images by the human brain. Magellium is involved in high performance image processing chains for satellite image processing as well as scientific signal analysis and geographic information management since its creation (2003). We believe that recent work on big data, GPU and peer-to-peer collaborative processing can open a new breakthrough in data analysis and display that will serve many new applications in collaborative scientific computing, environment mapping and understanding. The magHD (for Magellium Hyper-Dimension) project aims at developing software solutions that will bring highly interactive tools for complex datasets analysis and exploration commodity hardware, targeting small to medium scale clusters with expansion capabilities to large cloud based clusters.

Knowledge production and learning for sustainable landscapes: seven steps using social-ecological systems as laboratories.

PubMed

Angelstam, Per; Elbakidze, Marine; Axelsson, Robert; Dixelius, Malcolm; Törnblom, Johan

2013-03-01

There are multiple challenges regarding use and governance of landscapes' goods, functions and intangible values for ecosystem health and human well-being. One group of challenges is to measure and assess principal sustainability dimensions through performance targets, so stakeholders have transparent information about states and trends. Another group is to develop adaptive governance at multiple levels, and management of larger geographical areas across scales. Addressing these challenges, we present a framework for transdisciplinary research using multiple landscapes as place-based case studies that integrates multiple research disciplines and non-academic actors: (1) identify a suite of landscapes, and for each (2) review landscape history, (3) map stakeholders, use and non-use values, products and land use, (4) analyze institutions, policies and the system of governance, (5) measure ecological, economic, social and cultural sustainability, (6) assess sustainability dimensions and governance, and finally (7) make comparisons and synthesize. Collaboration, communication and dissemination are additional core features. We discuss barriers bridges and bridges for applying this approach.

Decoding Visual Location From Neural Patterns in the Auditory Cortex of the Congenitally Deaf

PubMed Central

Almeida, Jorge; He, Dongjun; Chen, Quanjing; Mahon, Bradford Z.; Zhang, Fan; Gonçalves, Óscar F.; Fang, Fang; Bi, Yanchao

2016-01-01

Sensory cortices of individuals who are congenitally deprived of a sense can exhibit considerable plasticity and be recruited to process information from the senses that remain intact. Here, we explored whether the auditory cortex of congenitally deaf individuals represents visual field location of a stimulus—a dimension that is represented in early visual areas. We used functional MRI to measure neural activity in auditory and visual cortices of congenitally deaf and hearing humans while they observed stimuli typically used for mapping visual field preferences in visual cortex. We found that the location of a visual stimulus can be successfully decoded from the patterns of neural activity in auditory cortex of congenitally deaf but not hearing individuals. This is particularly true for locations within the horizontal plane and within peripheral vision. These data show that the representations stored within neuroplastically changed auditory cortex can align with dimensions that are typically represented in visual cortex. PMID:26423461

Soil functional types: surveying the biophysical dimensions of soil security

NASA Astrophysics Data System (ADS)

Cécillon, Lauric; Barré, Pierre

2015-04-01

Soil is a natural capital that can deliver key ecosystem services (ES) to humans through the realization of a series of soil processes controlling ecosystem functioning. Soil is also a diverse and endangered natural resource. A huge pedodiversity has been described at all scales, which is strongly altered by global change. The multidimensional concept soil security, encompassing biophysical, economic, social, policy and legal frameworks of soils has recently been proposed, recognizing the role of soils in global environmental sustainability challenges. The biophysical dimensions of soil security focus on the functionality of a given soil that can be viewed as the combination of its capability and its condition [1]. Indeed, all soils are not equal in term of functionality. They show different processes, provide different ES to humans and respond specifically to global change. Knowledge of soil functionality in space and time is thus a crucial step towards the achievement soil security. All soil classification systems incorporate some functional information, but soil taxonomy alone cannot fully describe the functioning, limitations, resistance and resilience of soils. Droogers and Bouma [2] introduced functional variants (phenoforms) for each soil type (genoform) so as to fit more closely to soil functionality. However, different genoforms can have the same functionality. As stated by McBratney and colleagues [1], there is a great need of an agreed methodology for defining the reference state of soil functionality. Here, we propose soil functional types (SFT) as a relevant classification system for the biophysical dimensions of soil security. Following the definition of plant functional types widely used in ecology, we define a soil functional type as "a set of soil taxons or phenoforms sharing similar processes (e.g. soil respiration), similar effects on ecosystem functioning (e.g. primary productivity) and similar responses to global change (land-use, management or climate) for a particular soil-provided ecosystem service (e.g. climate regulation)". One SFT can thus include several soil types having the same functionality for a particular soil-provided ES. Another consequence is that SFT maps for two different ES may not superimpose over the same area, since some soils may fall in the same SFT for a service and in different SFT for another one. Soil functional types could be assessed and monitored in space and time by a combination of soil functional traits that correspond to inherent and manageable properties of soils. Their metrology would involve either classic (pedological observations) or advanced (molecular ecology, spectrometry, geophysics) tools. SFT could be studied and mapped at all scales, depending on the purpose of the soil security assessment (e.g. global climate modeling, land planning and management, biodiversity conservation). Overall, research is needed to find a pathway from soil pedological maps to SFT maps which would yield important benefits towards the assessment and monitoring of soil security. Indeed, this methodology would allow (i) reducing the spatial uncertainty on the assessment of ES; (ii) identifying and mapping multifunctional soils, which may be the most important soil resource to preserve. References [1] McBratney et al., 2014. Geoderma 213:203-213. [2] Droogers P, Bouma J, 1997. SSSAJ 61:1704-1710.

Infants learn better from left to right: a directional bias in infants' sequence learning.

PubMed

Bulf, Hermann; de Hevia, Maria Dolores; Gariboldi, Valeria; Macchi Cassia, Viola

2017-05-26

A wealth of studies show that human adults map ordered information onto a directional spatial continuum. We asked whether mapping ordinal information into a directional space constitutes an early predisposition, already functional prior to the acquisition of symbolic knowledge and language. While it is known that preverbal infants represent numerical order along a left-to-right spatial continuum, no studies have investigated yet whether infants, like adults, organize any kind of ordinal information onto a directional space. We investigated whether 7-month-olds' ability to learn high-order rule-like patterns from visual sequences of geometric shapes was affected by the spatial orientation of the sequences (left-to-right vs. right-to-left). Results showed that infants readily learn rule-like patterns when visual sequences were presented from left to right, but not when presented from right to left. This result provides evidence that spatial orientation critically determines preverbal infants' ability to perceive and learn ordered information in visual sequences, opening to the idea that a left-to-right spatially organized mental representation of ordered dimensions might be rooted in biologically-determined constraints on human brain development.

Reparameterization of PAM50 Expression Identifies Novel Breast Tumor Dimensions and Leads to Discovery of a Genome-Wide Significant Breast Cancer Locus at 12q15.

PubMed

Madsen, Michael J; Knight, Stacey; Sweeney, Carol; Factor, Rachel; Salama, Mohamed; Stijleman, Inge J; Rajamanickam, Venkatesh; Welm, Bryan E; Arunachalam, Sasi; Jones, Brandt; Rachamadugu, Rakesh; Rowe, Kerry; Cessna, Melissa H; Thomas, Alun; Kushi, Lawrence H; Caan, Bette J; Bernard, Philip S; Camp, Nicola J

2018-06-01

Background: Breast tumor subtyping has failed to provide impact in susceptibility genetics. The PAM50 assay categorizes breast tumors into: Luminal A, Luminal B, HER2-enriched and Basal-like. However, tumors are often more complex than simple categorization can describe. The identification of heritable tumor characteristics has potential to decrease heterogeneity and increase power for gene finding. Methods: We used 911 sporadic breast tumors with PAM50 expression data to derive tumor dimensions using principal components (PC). Dimensions in 238 tumors from high-risk pedigrees were compared with the sporadic tumors. Proof-of-concept gene mapping, informed by tumor dimension, was performed using Shared Genomic Segment (SGS) analysis. Results: Five dimensions (PC1-5) explained the majority of the PAM50 expression variance: three captured intrinsic subtype, two were novel (PC3, PC5). All five replicated in 745 TCGA tumors. Both novel dimensions were significantly enriched in the high-risk pedigrees (intrinsic subtypes were not). SGS gene-mapping in a pedigree identified a 0.5 Mb genome-wide significant region at 12q15 This region segregated through 32 meioses to 8 breast cancer cases with extreme PC3 tumors ( P = 2.6 × 10 -8 ). Conclusions: PC analysis of PAM50 gene expression revealed multiple independent, quantitative measures of tumor diversity. These tumor dimensions show evidence for heritability and potential as powerful traits for gene mapping. Impact: Our study suggests a new approach to describe tumor expression diversity, provides new avenues for germline studies, and proposes a new breast cancer locus. Similar reparameterization of expression patterns may inform other studies attempting to model the effects of tumor heterogeneity. Cancer Epidemiol Biomarkers Prev; 27(6); 644-52. ©2018 AACR . ©2018 American Association for Cancer Research.

Cognitive Maps as a Way of Presenting the Dimension of Comparison within the History of Psychology.

ERIC Educational Resources Information Center

Diekhoff, George M.

1982-01-01

Describes how cognitive maps can help to stimulate discussion of the structural inter-relationships of psychological theory in college-level history of psychology classes. The author describes a cognitive mapping activity in which students pair prominent theorists and theories, rate their degrees of similarity, and graph the relationships of their…

2.5D Multi-View Gait Recognition Based on Point Cloud Registration

PubMed Central

Tang, Jin; Luo, Jian; Tjahjadi, Tardi; Gao, Yan

2014-01-01

This paper presents a method for modeling a 2.5-dimensional (2.5D) human body and extracting the gait features for identifying the human subject. To achieve view-invariant gait recognition, a multi-view synthesizing method based on point cloud registration (MVSM) to generate multi-view training galleries is proposed. The concept of a density and curvature-based Color Gait Curvature Image is introduced to map 2.5D data onto a 2D space to enable data dimension reduction by discrete cosine transform and 2D principle component analysis. Gait recognition is achieved via a 2.5D view-invariant gait recognition method based on point cloud registration. Experimental results on the in-house database captured by a Microsoft Kinect camera show a significant performance gain when using MVSM. PMID:24686727

Characterization of relief printing

NASA Astrophysics Data System (ADS)

Liu, Xing; Chen, Lin; Ortiz-Segovia, Maria-Valezzka; Ferwerda, James; Allebach, Jan

2014-03-01

Relief printing technology developed by Océ allows the superposition of several layers of colorant on different types of media which creates a variation of the surface height defined by the input to the printer. Evaluating the reproduction accuracy of distinct surface characteristics is of great importance to the application of the relief printing system. Therefore, it is necessary to develop quality metrics to evaluate the relief process. In this paper, we focus on the third dimension of relief printing, i.e. height information. To achieve this goal, we define metrics and develop models that aim to evaluate relief prints in two aspects: overall fidelity and surface finish. To characterize the overall fidelity, three metrics are calculated: Modulation Transfer Function (MTF), difference and root-mean-squared error (RMSE) between the input height map and scanned height map, and print surface angle accuracy. For the surface finish property, we measure the surface roughness, generate surface normal maps and develop a light reflection model that serves as a simulation of the differences between ideal prints and real prints that may be perceived by human observers. Three sets of test targets are designed and printed by the Océ relief printer prototypes for the calculation of the above metrics: (i) twisted target, (ii) sinusoidal wave target, and (iii) ramp target. The results provide quantitative evaluations of the printing quality in the third dimension, and demonstrate that the height of relief prints is reproduced accurately with respect to the input design. The factors that affect the printing quality include: printing direction, frequency and amplitude of the input signal, shape of relief prints. Besides the above factors, there are two additional aspects that influence the viewing experience of relief prints: lighting condition and viewing angle.

Toward Cosmopolitan Ethics in Teacher Education: An Ontological Dimension of Learning Human Rights

ERIC Educational Resources Information Center

Adami, Rebecca

2014-01-01

There is a globalization trend in teacher education, emphasizing the role of teachers to make judgments based on human rights in their teaching profession. Rather than emphasizing the epistemological dimension of acquiring knowledge "about" human rights through teacher education, an ontological dimension is emphasized in this paper of…

The Small Body Mapping Tool (SBMT) for Accessing, Visualizing, and Analyzing Spacecraft Data in Three Dimensions

NASA Astrophysics Data System (ADS)

Barnouin, O. S.; Ernst, C. M.; Daly, R. T.

2018-04-01

The free, publicly available Small Body Mapping Tool (SBMT) developed at the Johns Hopkins University Applied Physics Laboratory is a powerful, easy-to-use tool for accessing and analyzing data from small bodies.

Projective mappings and dimensions of vector spaces of three types of Killing-Yano tensors on pseudo Riemannian manifolds of constant curvature

NASA Astrophysics Data System (ADS)

Mikeš, Josef; Stepanov, Sergey; Hinterleitner, Irena

2012-07-01

In our paper we have determined the dimension of the space of conformal Killing-Yano tensors and the dimensions of its two subspaces of closed conformal Killing-Yano and Killing-Yano tensors on pseudo Riemannian manifolds of constant curvature. This result is a generalization of well known results on sharp upper bounds of the dimensions of the vector spaces of conformal Killing-Yano, Killing-Yano and concircular vector fields on pseudo Riemannian manifolds of constant curvature.

Distortion correction in EPI at ultra-high-field MRI using PSF mapping with optimal combination of shift detection dimension.

PubMed

Oh, Se-Hong; Chung, Jun-Young; In, Myung-Ho; Zaitsev, Maxim; Kim, Young-Bo; Speck, Oliver; Cho, Zang-Hee

2012-10-01

Despite its wide use, echo-planar imaging (EPI) suffers from geometric distortions due to off-resonance effects, i.e., strong magnetic field inhomogeneity and susceptibility. This article reports a novel method for correcting the distortions observed in EPI acquired at ultra-high-field such as 7 T. Point spread function (PSF) mapping methods have been proposed for correcting the distortions in EPI. The PSF shift map can be derived either along the nondistorted or the distorted coordinates. Along the nondistorted coordinates more information about compressed areas is present but it is prone to PSF-ghosting artifacts induced by large k-space shift in PSF encoding direction. In contrast, shift maps along the distorted coordinates contain more information in stretched areas and are more robust against PSF-ghosting. In ultra-high-field MRI, an EPI contains both compressed and stretched regions depending on the B0 field inhomogeneity and local susceptibility. In this study, we present a new geometric distortion correction scheme, which selectively applies the shift map with more information content. We propose a PSF-ghost elimination method to generate an artifact-free pixel shift map along nondistorted coordinates. The proposed method can correct the effects of the local magnetic field inhomogeneity induced by the susceptibility effects along with the PSF-ghost artifact cancellation. We have experimentally demonstrated the advantages of the proposed method in EPI data acquisitions in phantom and human brain using 7-T MRI. Copyright © 2011 Wiley Periodicals, Inc.

Human handling and presentation of a novel object evoke independent dimensions of fear in Japanese quail.

PubMed

Richard, S; Land, N; Saint-Dizier, H; Leterrier, C; Faure, J M

2010-09-01

Fear is a concept comprising several dimensions, but the nature of these dimensions and the relationships between them remain elusive. To investigate these dimensions in birds, we have used two genetic lines of quail divergently selected on tonic immobility duration, a behavioural index of fear. These two lines differ in their behavioural response to some, but not all, fear-inducing situations. In the present study, we investigated the contribution of human intervention in the differentiation between the two lines. To do this, fear responses towards a novel object were compared between lines in three conditions: (1) in the home cage without any human intervention, (2) in the home cage after human handling and (3) after placement in a novel environment by human handling. Fear behaviour differed between lines after human handling, with or without placement in a novel environment, but presentation of a novel object in the home cage without any human intervention induced similar fear responses in the two lines of quail. These results lead us to suggest that in quail, human intervention evokes a dimension of fear that differs from that evoked by sudden presentation of a novel object, in that these two dimensions may be selected independently. Copyright 2010 Elsevier B.V. All rights reserved.

Hematopoiesis in 3 dimensions: human and murine bone marrow architecture visualized by confocal microscopy.

PubMed

Takaku, Tomoiku; Malide, Daniela; Chen, Jichun; Calado, Rodrigo T; Kajigaya, Sachiko; Young, Neal S

2010-10-14

In many animals, blood cell production occurs in the bone marrow. Hematopoiesis is complex, requiring self-renewing and pluripotent stem cells, differentiated progenitor and precursor cells, and supportive stroma, adipose tissue, vascular structures, and extracellular matrix. Although imaging is a vital tool in hematology research, the 3-dimensional architecture of the bone marrow tissue in situ remains largely uncharacterized. The major hindrance to imaging the intact marrow is the surrounding bone structures are almost impossible to cut/image through. We have overcome these obstacles and describe a method whereby whole-mounts of bone marrow tissue were immunostained and imaged in 3 dimensions by confocal fluorescence and reflection microscopy. We have successfully mapped by multicolor immunofluorescence the localization pattern of as many as 4 cell features simultaneously over large tiled views and to depths of approximately 150 μm. Three-dimensional images can be assessed qualitatively and quantitatively to appreciate the distribution of cell types and their interrelationships, with minimal perturbations of the tissue. We demonstrate its application to normal mouse and human marrow, to murine models of marrow failure, and to patients with aplastic anemia, myeloid, and lymphoid cell malignancies. The technique should be generally adaptable for basic laboratory investigation and for clinical diagnosis of hematologic diseases.

The baker’s map with a convex hole

NASA Astrophysics Data System (ADS)

Clark, Lyndsey; Hare, Kevin G.; Sidorov, Nikita

2018-07-01

We consider the baker’s map B on the unit square X and an open convex set which we regard as a hole. The survivor set is defined as the set of all points in X whose B-trajectories are disjoint from H. The main purpose of this paper is to study holes H for which (dimension traps) as well as those for which any periodic trajectory of B intersects (cycle traps). We show that any H which lies in the interior of X is not a dimension trap. This means that, unlike the doubling map and other one-dimensional examples, we can have for H whose Lebesgue measure is arbitrarily close to one. Also, we describe holes which are dimension or cycle traps, critical in the sense that if we consider a strictly convex subset, then the corresponding property in question no longer holds. We also determine such that for all convex H whose Lebesgue measure is less than δ. This paper may be seen as a first extension of our work begun in Clark (2016 Discrete Continuous Dyn. Syst. A 6 1249–69 Clark 2016 PhD Dissertation The University of Manchester; Glendinning and Sidorov 2015 Ergod. Theor. Dynam. Syst. 35 1208–28 Hare and Sidorov 2014 Mon.hefte Math. 175 347–65 Sidorov 2014 Acta Math. Hung. 143 298–312) to higher dimensions.

Using GIS for spatial analysis of rectal lesions in the human body.

PubMed

Garb, Jane L; Ganai, Sabha; Skinner, Ric; Boyd, Christopher S; Wait, Richard B

2007-03-15

Geographic Information Systems (GIS) have been used in a wide variety of applications to integrate data and explore the spatial relationship of geographic features. Traditionally this has referred to features on the surface of the earth. However, it is possible to apply GIS in medicine, at the scale of the human body, to visualize and analyze anatomic and clinical features. In the present study we used GIS to examine the findings of transanal endoscopic microsurgery (TEM), a minimally-invasive procedure to locate and remove both benign and cancerous lesions of the rectum. Our purpose was to determine whether anatomic features of the human rectum and clinical findings at the time of surgery could be rendered in a GIS and spatially analyzed for their relationship to clinical outcomes. Maps of rectal topology were developed in two and three dimensions. These maps highlight anatomic features of the rectum and the location of lesions found on TEM. Spatial analysis demonstrated a significant relationship between anatomic location of the lesion and procedural failure. This study demonstrates the feasibility of rendering anatomical locations and clinical events in a GIS and its value in clinical research. This allows the visualization and spatial analysis of clinical and pathologic features, increasing our awareness of the relationship between anatomic features and clinical outcomes as well as enhancing our understanding and management of this disease process.

Using GIS for spatial analysis of rectal lesions in the human body

PubMed Central

Garb, Jane L; Ganai, Sabha; Skinner, Ric; Boyd, Christopher S; Wait, Richard B

2007-01-01

Background Geographic Information Systems (GIS) have been used in a wide variety of applications to integrate data and explore the spatial relationship of geographic features. Traditionally this has referred to features on the surface of the earth. However, it is possible to apply GIS in medicine, at the scale of the human body, to visualize and analyze anatomic and clinical features. In the present study we used GIS to examine the findings of transanal endoscopic microsurgery (TEM), a minimally-invasive procedure to locate and remove both benign and cancerous lesions of the rectum. Our purpose was to determine whether anatomic features of the human rectum and clinical findings at the time of surgery could be rendered in a GIS and spatially analyzed for their relationship to clinical outcomes. Results Maps of rectal topology were developed in two and three dimensions. These maps highlight anatomic features of the rectum and the location of lesions found on TEM. Spatial analysis demonstrated a significant relationship between anatomic location of the lesion and procedural failure. Conclusion This study demonstrates the feasibility of rendering anatomical locations and clinical events in a GIS and its value in clinical research. This allows the visualization and spatial analysis of clinical and pathologic features, increasing our awareness of the relationship between anatomic features and clinical outcomes as well as enhancing our understanding and management of this disease process. PMID:17362510

Self-Organizing-Map Program for Analyzing Multivariate Data

NASA Technical Reports Server (NTRS)

Li, P. Peggy; Jacob, Joseph C.; Block, Gary L.; Braverman, Amy J.

2005-01-01

SOM_VIS is a computer program for analysis and display of multidimensional sets of Earth-image data typified by the data acquired by the Multi-angle Imaging Spectro-Radiometer [MISR (a spaceborne instrument)]. In SOM_VIS, an enhanced self-organizing-map (SOM) algorithm is first used to project a multidimensional set of data into a nonuniform three-dimensional lattice structure. The lattice structure is mapped to a color space to obtain a color map for an image. The Voronoi cell-refinement algorithm is used to map the SOM lattice structure to various levels of color resolution. The final result is a false-color image in which similar colors represent similar characteristics across all its data dimensions. SOM_VIS provides a control panel for selection of a subset of suitably preprocessed MISR radiance data, and a control panel for choosing parameters to run SOM training. SOM_VIS also includes a component for displaying the false-color SOM image, a color map for the trained SOM lattice, a plot showing an original input vector in 36 dimensions of a selected pixel from the SOM image, the SOM vector that represents the input vector, and the Euclidean distance between the two vectors.

The North America tapestry of time and terrain

USGS Publications Warehouse

Barton, Kate E.; Howell, David G.; Vigil, Jose F.

2003-01-01

The North America Tapestry of Time and Terrain (1:8,000,000 scale) is a product of the US Geological Survey in the I-map series (I-2781). This map was prepared in collaboration with the Geological Survey of Canada and the Mexican Consejo Recursos de Minerales. This cartographic Tapestry is woven from a geologic map and a shaded relief image. This digital combination reveals the geologic history of North America through the interrelation of rock type, topography and time. Regional surface processes as well as continent-scale tectonic events are exposed in the three dimensions of space and the fourth dimension, geologic time. The large map shows the varying age of bedrock underlying North America, while four smaller maps show the distribution of four principal types of rock: sedimentary, volcanic, plutonic and metamorphic.This map expands the original concept of the 2000 Tapestry of Time and Terrain, by José F. Vigil, Richard J. Pike and David G. Howell, which covered the conterminous United States. The U.S. Tapestry poster and website have been popular in classrooms, homes, and even the Google office building, and we anticipate the North America Tapestry will have a similarly wide appeal, and to a larger audience.

True orbit simulation of piecewise linear and linear fractional maps of arbitrary dimension using algebraic numbers

NASA Astrophysics Data System (ADS)

Saito, Asaki; Yasutomi, Shin-ichi; Tamura, Jun-ichi; Ito, Shunji

2015-06-01

We introduce a true orbit generation method enabling exact simulations of dynamical systems defined by arbitrary-dimensional piecewise linear fractional maps, including piecewise linear maps, with rational coefficients. This method can generate sufficiently long true orbits which reproduce typical behaviors (inherent behaviors) of these systems, by properly selecting algebraic numbers in accordance with the dimension of the target system, and involving only integer arithmetic. By applying our method to three dynamical systems—that is, the baker's transformation, the map associated with a modified Jacobi-Perron algorithm, and an open flow system—we demonstrate that it can reproduce their typical behaviors that have been very difficult to reproduce with conventional simulation methods. In particular, for the first two maps, we show that we can generate true orbits displaying the same statistical properties as typical orbits, by estimating the marginal densities of their invariant measures. For the open flow system, we show that an obtained true orbit correctly converges to the stable period-1 orbit, which is inherently possessed by the system.

Electrophysiological correlates of preparation and implementation for different types of task shifts.

PubMed

Hsieh, Shulan; Wu, Mengyao

2011-11-14

The ability to flexibly shift between tasks is central to cognitive control, but whether the same brain mechanisms mediate shifting across different tasks is unknown. In this study, we investigated whether variations in stimulus-dimensions or response-mapping might influence task switching in terms of its preparatory processes, as reflected in cue-locked event-related potentials (ERPs), and its implementation processes, as reflected in stimulus-locked ERPs. Participants judged pairs of digits as same or different in one of two conditions. In one condition, the task-relevant stimulus-dimension was either repeated or switched across trials while the response-mapping rule was kept constant. In the other condition, the task-relevant stimulus-dimension was kept constant while the response-mapping rule was repeated or switched across trials. The length of the preparatory interval was manipulated. Data revealed switch-related preparatory ERP components (including N2 and a late slow positivity) that were associated with both types of task shifting and an N400-like negativity that distinguished between the two types. Several switch-related implementation ERP components associated with both types of task shifting were found at posterior sites. Distinct frontal modulations of the N1, P2, and N2 were found to associate with the implementation of the response-mapping shift, whereas a slow positivity was associated with the implementation of the stimulus-dimension shift. Therefore, this study demonstrates that there are shared and distinct processes across different types of task shifting. Finally, because the same transition-cue was used for different task shifts, the distinct processes cannot be explained simply by differences in cue processing. Copyright © 2011 Elsevier B.V. All rights reserved.

Ptychographic X-ray nanotomography quantifies mineral distributions in human dentine

NASA Astrophysics Data System (ADS)

Zanette, I.; Enders, B.; Dierolf, M.; Thibault, P.; Gradl, R.; Diaz, A.; Guizar-Sicairos, M.; Menzel, A.; Pfeiffer, F.; Zaslansky, P.

2015-03-01

Bones are bio-composites with biologically tunable mechanical properties, where a polymer matrix of nanofibrillar collagen is reinforced by apatite mineral crystals. Some bones, such as antler, form and change rapidly, while other bone tissues, such as human tooth dentine, develop slowly and maintain constant composition and architecture for entire lifetimes. When studying apatite mineral microarchitecture, mineral distributions or mineralization activity of bone-forming cells, representative samples of tissue are best studied at submicrometre resolution while minimizing sample-preparation damage. Here, we demonstrate the power of ptychographic X-ray tomography to map variations in the mineral content distribution in three dimensions and at the nanometre scale. Using this non-destructive method, we observe nanostructures surrounding hollow tracts that exist in human dentine forming dentinal tubules. We reveal unprecedented quantitative details of the ultrastructure clearly revealing the spatially varying mineralization density. Such information is essential for understanding a variety of natural and therapeutic effects for example in bone tissue healing and ageing.

Operant conditioning of a multiple degree-of-freedom brain-machine interface in a primate model of amputation.

PubMed

Balasubramanian, Karthikeyan; Southerland, Joshua; Vaidya, Mukta; Qian, Kai; Eleryan, Ahmed; Fagg, Andrew H; Sluzky, Marc; Oweiss, Karim; Hatsopoulos, Nicholas

2013-01-01

Operant conditioning with biofeedback has been shown to be an effective method to modify neural activity to generate goal-directed actions in a brain-machine interface. It is particularly useful when neural activity cannot be mathematically mapped to motor actions of the actual body such as in the case of amputation. Here, we implement an operant conditioning approach with visual feedback in which an amputated monkey is trained to control a multiple degree-of-freedom robot to perform a reach-to-grasp behavior. A key innovation is that each controlled dimension represents a behaviorally relevant synergy among a set of joint degrees-of-freedom. We present a number of behavioral metrics by which to assess improvements in BMI control with exposure to the system. The use of non-human primates with chronic amputation is arguably the most clinically-relevant model of human amputation that could have direct implications for developing a neural prosthesis to treat humans with missing upper limbs.

Methodological dimensions of transcranial brain stimulation with the electrical current in human.

PubMed

Rostami, Maryam; Golesorkhi, Mehrshad; Ekhtiari, Hamed

2013-01-01

Transcranial current stimulation (TCS) is a neuromodulation method in which the patient is exposed to a mild electric current (direct or alternating) at 1-2 mA, resulting in an increase or a decrease in the brain excitability. This modification in neural activities can be used as a method for functional human brain mapping with causal inferences. This method might also facilitate the treatments of many neuropsychiatric disorders based on its inexpensive, simple, safe, noninvasive, painless, semi-focal excitatory and inhibitory effects. Given this, a comparison amongst different brain stimulation modalities has been made to determine the potential advantages of the TCS method. In addition, considerable methodological details on using TCS in basic and clinical neuroscience studies in human subjects have been introduced. Technical characteristics of TCS devices and their related accessories with regard to safety concerns have also been well articulated. Finally, some TCS application opportunities have been emphasized, including its potential use in the near future.

Fractal dimension of spatially extended systems

NASA Astrophysics Data System (ADS)

Torcini, A.; Politi, A.; Puccioni, G. P.; D'Alessandro, G.

1991-10-01

Properties of the invariant measure are numerically investigated in 1D chains of diffusively coupled maps. The coarse-grained fractal dimension is carefully computed in various embedding spaces, observing an extremely slow convergence towards the asymptotic value. This is in contrast with previous simulations, where the analysis of an insufficient number of points led the authors to underestimate the increase of fractal dimension with increasing the dimension of the embedding space. Orthogonal decomposition is also performed confirming that the slow convergence is intrinsically related to local nonlinear properties of the invariant measure. Finally, the Kaplan-Yorke conjecture is tested for short chains, showing that, despite the noninvertibility of the dynamical system, a good agreement is found between Lyapunov dimension and information dimension.

Seismic Tomography.

ERIC Educational Resources Information Center

Anderson, Don L.; Dziewonski, Adam M.

1984-01-01

Describes how seismic tomography is used to analyze the waves produced by earthquakes. The information obtained from the procedure can then be used to map the earth's mantle in three dimensions. The resulting maps are then studied to determine such information as the convective flow that propels the crustal plates. (JN)

Robust visual object tracking with interleaved segmentation

NASA Astrophysics Data System (ADS)

Abel, Peter; Kieritz, Hilke; Becker, Stefan; Arens, Michael

2017-10-01

In this paper we present a new approach for tracking non-rigid, deformable objects by means of merging an on-line boosting-based tracker and a fast foreground background segmentation. We extend an on-line boosting- based tracker, which uses axes-aligned bounding boxes with fixed aspect-ratio as tracking states. By constructing a confidence map from the on-line boosting-based tracker and unifying this map with a confidence map, which is obtained from a foreground background segmentation algorithm, we build a superior confidence map. For constructing a rough confidence map of a new frame based on on-line boosting, we employ the responses of the strong classifier as well as the single weak classifier responses that were built before during the updating step. This confidence map provides a rough estimation of the object's position and dimension. In order to refine this confidence map, we build a fine, pixel-wisely segmented confidence map and merge both maps together. Our segmentation method is color-histogram-based and provides a fine and fast image segmentation. By means of back-projection and the Bayes' rule, we obtain a confidence value for every pixel. The rough and the fine confidence maps are merged together by building an adaptively weighted sum of both maps. The weights are obtained by utilizing the variances of both confidence maps. Further, we apply morphological operators in the merged confidence map in order to reduce the noise. In the resulting map we estimate the object localization and dimension via continuous adaptive mean shift. Our approach provides a rotated rectangle as tracking states, which enables a more precise description of non-rigid, deformable objects than axes-aligned bounding boxes. We evaluate our tracker on the visual object tracking (VOT) benchmark dataset 2016.

The Iron Law of Hierarchy? Institutional Differentiation in UK Higher Education

ERIC Educational Resources Information Center

Croxford, Linda; Raffe, David

2015-01-01

This paper maps the main dimensions of differentiation among institutions and "faculties" (subject areas within institutions) of higher education in the United Kingdom. It does so through a principal components analysis based on the characteristics of applicants and entrants. A single status dimension accounts for a quarter of the…

Consistent global structures of complex RNA states through multidimensional chemical mapping

PubMed Central

Cheng, Clarence Yu; Chou, Fang-Chieh; Kladwang, Wipapat; Tian, Siqi; Cordero, Pablo; Das, Rhiju

2015-01-01

Accelerating discoveries of non-coding RNA (ncRNA) in myriad biological processes pose major challenges to structural and functional analysis. Despite progress in secondary structure modeling, high-throughput methods have generally failed to determine ncRNA tertiary structures, even at the 1-nm resolution that enables visualization of how helices and functional motifs are positioned in three dimensions. We report that integrating a new method called MOHCA-seq (Multiplexed •OH Cleavage Analysis with paired-end sequencing) with mutate-and-map secondary structure inference guides Rosetta 3D modeling to consistent 1-nm accuracy for intricately folded ncRNAs with lengths up to 188 nucleotides, including a blind RNA-puzzle challenge, the lariat-capping ribozyme. This multidimensional chemical mapping (MCM) pipeline resolves unexpected tertiary proximities for cyclic-di-GMP, glycine, and adenosylcobalamin riboswitch aptamers without their ligands and a loose structure for the recently discovered human HoxA9D internal ribosome entry site regulon. MCM offers a sequencing-based route to uncovering ncRNA 3D structure, applicable to functionally important but potentially heterogeneous states. DOI: http://dx.doi.org/10.7554/eLife.07600.001 PMID:26035425

Continuous wireless pressure monitoring and mapping with ultra-small passive sensors for health monitoring and critical care

NASA Astrophysics Data System (ADS)

Chen, Lisa Y.; Tee, Benjamin C.-K.; Chortos, Alex L.; Schwartz, Gregor; Tse, Victor; J. Lipomi, Darren; Wong, H.-S. Philip; McConnell, Michael V.; Bao, Zhenan

2014-10-01

Continuous monitoring of internal physiological parameters is essential for critical care patients, but currently can only be practically achieved via tethered solutions. Here we report a wireless, real-time pressure monitoring system with passive, flexible, millimetre-scale sensors, scaled down to unprecedented dimensions of 1 × 1 × 0.1 cubic millimeters. This level of dimensional scaling is enabled by novel sensor design and detection schemes, which overcome the operating frequency limits of traditional strategies and exhibit insensitivity to lossy tissue environments. We demonstrate the use of this system to capture human pulse waveforms wirelessly in real time as well as to monitor in vivo intracranial pressure continuously in proof-of-concept mice studies using sensors down to 2.5 × 2.5 × 0.1 cubic millimeters. We further introduce printable wireless sensor arrays and show their use in real-time spatial pressure mapping. Looking forward, this technology has broader applications in continuous wireless monitoring of multiple physiological parameters for biomedical research and patient care.

Continuous wireless pressure monitoring and mapping with ultra-small passive sensors for health monitoring and critical care.

PubMed

Chen, Lisa Y; Tee, Benjamin C-K; Chortos, Alex L; Schwartz, Gregor; Tse, Victor; Lipomi, Darren J; Wong, H-S Philip; McConnell, Michael V; Bao, Zhenan

2014-10-06

Continuous monitoring of internal physiological parameters is essential for critical care patients, but currently can only be practically achieved via tethered solutions. Here we report a wireless, real-time pressure monitoring system with passive, flexible, millimetre-scale sensors, scaled down to unprecedented dimensions of 1 × 1 × 0.1 cubic millimeters. This level of dimensional scaling is enabled by novel sensor design and detection schemes, which overcome the operating frequency limits of traditional strategies and exhibit insensitivity to lossy tissue environments. We demonstrate the use of this system to capture human pulse waveforms wirelessly in real time as well as to monitor in vivo intracranial pressure continuously in proof-of-concept mice studies using sensors down to 2.5 × 2.5 × 0.1 cubic millimeters. We further introduce printable wireless sensor arrays and show their use in real-time spatial pressure mapping. Looking forward, this technology has broader applications in continuous wireless monitoring of multiple physiological parameters for biomedical research and patient care.

Why is the sunny side always up? Explaining the spatial mapping of concepts by language use.

PubMed

Goodhew, Stephanie C; McGaw, Bethany; Kidd, Evan

2014-10-01

Humans appear to rely on spatial mappings to represent and describe concepts. The conceptual cuing effect describes the tendency for participants to orient attention to a spatial location following the presentation of an unrelated cue word (e.g., orienting attention upward after reading the word sky). To date, such effects have predominately been explained within the embodied cognition framework, according to which people's attention is oriented on the basis of prior experience (e.g., sky → up via perceptual simulation). However, this does not provide a compelling explanation for how abstract words have the same ability to orient attention. Why, for example, does dream also orient attention upward? We report on an experiment that investigated the role of language use (specifically, collocation between concept words and spatial words for up and down dimensions) and found that it predicted the cuing effect. The results suggest that language usage patterns may be instrumental in explaining conceptual cuing.

Universal map for cellular automata

NASA Astrophysics Data System (ADS)

García-Morales, V.

2012-08-01

A universal map is derived for all deterministic 1D cellular automata (CAs) containing no freely adjustable parameters and valid for any alphabet size and any neighborhood range (including non-symmetrical neighborhoods). The map can be extended to an arbitrary number of dimensions and topologies and to arbitrary order in time. Specific CA maps for the famous Conway's Game of Life and Wolfram's 256 elementary CAs are given. An induction method for CAs, based in the universal map, allows mathematical expressions for the orbits of a wide variety of elementary CAs to be systematically derived.

Changes in federal agencies panel: human dimensions research and ecosystem management: policy and research implications for recreation research efforts

Treesearch

Alan Ewert

1995-01-01

With an increased emphasis being placed on ecosystem management, the importance of Human Dimension Research (HDR) efforts in management and policy formulation are becoming more important. Developing an understanding of the type of management questions and policy needs that can be addressed by human dimension research is becoming increasingly important and timely. This...

Social Network Map: Some Further Refinements on Administration.

ERIC Educational Resources Information Center

Tracy, Elizabeth M.; Abell, Neil

1994-01-01

Notes that social network mapping techniques have been advanced as means of assessing social and environmental resources. Addresses issue of convergent construct validity, correlations among dimensions of perceived social support as measured by social network data with other standardized social support instruments. Findings confirm that structural…

Novel method of finding extreme edges in a convex set of N-dimension vectors

NASA Astrophysics Data System (ADS)

Hu, Chia-Lun J.

2001-11-01

As we published in the last few years, for a binary neural network pattern recognition system to learn a given mapping {Um mapped to Vm, m=1 to M} where um is an N- dimension analog (pattern) vector, Vm is a P-bit binary (classification) vector, the if-and-only-if (IFF) condition that this network can learn this mapping is that each i-set in {Ymi, m=1 to M} (where Ymithere existsVmiUm and Vmi=+1 or -1, is the i-th bit of VR-m).)(i=1 to P and there are P sets included here.) Is POSITIVELY, LINEARLY, INDEPENDENT or PLI. We have shown that this PLI condition is MORE GENERAL than the convexity condition applied to a set of N-vectors. In the design of old learning machines, we know that if a set of N-dimension analog vectors form a convex set, and if the machine can learn the boundary vectors (or extreme edges) of this set, then it can definitely learn the inside vectors contained in this POLYHEDRON CONE. This paper reports a new method and new algorithm to find the boundary vectors of a convex set of ND analog vectors.

Mapping QTLs controlling kernel dimensions in a wheat inter-varietal RIL mapping population.

PubMed

Cheng, Ruiru; Kong, Zhongxin; Zhang, Liwei; Xie, Quan; Jia, Haiyan; Yu, Dong; Huang, Yulong; Ma, Zhengqiang

2017-07-01

Seven kernel dimension QTLs were identified in wheat, and kernel thickness was found to be the most important dimension for grain weight improvement. Kernel morphology and weight of wheat (Triticum aestivum L.) affect both yield and quality; however, the genetic basis of these traits and their interactions has not been fully understood. In this study, to investigate the genetic factors affecting kernel morphology and the association of kernel morphology traits with kernel weight, kernel length (KL), width (KW) and thickness (KT) were evaluated, together with hundred-grain weight (HGW), in a recombinant inbred line population derived from Nanda2419 × Wangshuibai, with data from five trials (two different locations over 3 years). The results showed that HGW was more closely correlated with KT and KW than with KL. A whole genome scan revealed four QTLs for KL, one for KW and two for KT, distributed on five different chromosomes. Of them, QKl.nau-2D for KL, and QKt.nau-4B and QKt.nau-5A for KT were newly identified major QTLs for the respective traits, explaining up to 32.6 and 41.5% of the phenotypic variations, respectively. Increase of KW and KT and reduction of KL/KT and KW/KT ratios always resulted in significant higher grain weight. Lines combining the Nanda 2419 alleles of the 4B and 5A intervals had wider, thicker, rounder kernels and a 14% higher grain weight in the genotype-based analysis. A strong, negative linear relationship of the KW/KT ratio with grain weight was observed. It thus appears that kernel thickness is the most important kernel dimension factor in wheat improvement for higher yield. Mapping and marker identification of the kernel dimension-related QTLs definitely help realize the breeding goals.

Are numbers, size and brightness equally efficient in orienting visual attention? Evidence from an eye-tracking study.

PubMed

Bulf, Hermann; Macchi Cassia, Viola; de Hevia, Maria Dolores

2014-01-01

A number of studies have shown strong relations between numbers and oriented spatial codes. For example, perceiving numbers causes spatial shifts of attention depending upon numbers' magnitude, in a way suggestive of a spatially oriented, mental representation of numbers. Here, we investigated whether this phenomenon extends to non-symbolic numbers, as well as to the processing of the continuous dimensions of size and brightness, exploring whether different quantitative dimensions are equally mapped onto space. After a numerical (symbolic Arabic digits or non-symbolic arrays of dots; Experiment 1) or a non-numerical cue (shapes of different size or brightness level; Experiment 2) was presented, participants' saccadic response to a target that could appear either on the left or the right side of the screen was registered using an automated eye-tracker system. Experiment 1 showed that, both in the case of Arabic digits and dot arrays, right targets were detected faster when preceded by large numbers, and left targets were detected faster when preceded by small numbers. Participants in Experiment 2 were faster at detecting right targets when cued by large-sized shapes and left targets when cued by small-sized shapes, whereas brightness cues did not modulate the detection of peripheral targets. These findings indicate that looking at a symbolic or a non-symbolic number induces attentional shifts to a peripheral region of space that is congruent with the numbers' relative position on a mental number line, and that a similar shift in visual attention is induced by looking at shapes of different size. More specifically, results suggest that, while the dimensions of number and size spontaneously map onto an oriented space, the dimension of brightness seems to be independent at a certain level of magnitude elaboration from the dimensions of spatial extent and number, indicating that not all continuous dimensions are equally mapped onto space.

Importance of extended spatial coverage for quantitative susceptibility mapping of iron-rich deep gray matter.

PubMed

Elkady, Ahmed M; Sun, Hongfu; Wilman, Alan H

2016-05-01

Quantitative Susceptibility Mapping (QSM) is an emerging area of brain research with clear application to brain iron studies in deep gray matter. However, acquisition of standard whole brain QSM can be time-consuming. One means to reduce scan time is to use a focal acquisition restricted only to the regions of interest such as deep gray matter. However, the non-local dipole field necessary for QSM reconstruction extends far beyond the structure of interest. We demonstrate the practical implications of these non-local fields on the choice of brain volume for QSM. In an illustrative numerical simulation and then in human brain experiments, we examine the effect on QSM of volume reduction in each dimension. For the globus pallidus, as an example of iron-rich deep gray matter, we demonstrate that substantial errors can arise even when the field-of-view far exceeds the physical structural boundaries. Thus, QSM reconstruction requires a non-local field-of-view prescription to ensure minimal errors. An axial QSM acquisition, centered on the globus pallidus, should encompass at least 76mm in the superior-inferior direction to conserve susceptibility values from the globus pallidus. This dimension exceeds the physical coronal extent of this structure by at least five-fold. As QSM sees wider use in the neuroscience community, its unique requirement for an extended field-of-view needs to be considered. Copyright © 2016 Elsevier Inc. All rights reserved.

Exploring nonlinear feature space dimension reduction and data representation in breast Cadx with Laplacian eigenmaps and t-SNE.

PubMed

Jamieson, Andrew R; Giger, Maryellen L; Drukker, Karen; Li, Hui; Yuan, Yading; Bhooshan, Neha

2010-01-01

In this preliminary study, recently developed unsupervised nonlinear dimension reduction (DR) and data representation techniques were applied to computer-extracted breast lesion feature spaces across three separate imaging modalities: Ultrasound (U.S.) with 1126 cases, dynamic contrast enhanced magnetic resonance imaging with 356 cases, and full-field digital mammography with 245 cases. Two methods for nonlinear DR were explored: Laplacian eigenmaps [M. Belkin and P. Niyogi, "Laplacian eigenmaps for dimensionality reduction and data representation," Neural Comput. 15, 1373-1396 (2003)] and t-distributed stochastic neighbor embedding (t-SNE) [L. van der Maaten and G. Hinton, "Visualizing data using t-SNE," J. Mach. Learn. Res. 9, 2579-2605 (2008)]. These methods attempt to map originally high dimensional feature spaces to more human interpretable lower dimensional spaces while preserving both local and global information. The properties of these methods as applied to breast computer-aided diagnosis (CADx) were evaluated in the context of malignancy classification performance as well as in the visual inspection of the sparseness within the two-dimensional and three-dimensional mappings. Classification performance was estimated by using the reduced dimension mapped feature output as input into both linear and nonlinear classifiers: Markov chain Monte Carlo based Bayesian artificial neural network (MCMC-BANN) and linear discriminant analysis. The new techniques were compared to previously developed breast CADx methodologies, including automatic relevance determination and linear stepwise (LSW) feature selection, as well as a linear DR method based on principal component analysis. Using ROC analysis and 0.632+bootstrap validation, 95% empirical confidence intervals were computed for the each classifier's AUC performance. In the large U.S. data set, sample high performance results include, AUC0.632+ = 0.88 with 95% empirical bootstrap interval [0.787;0.895] for 13 ARD selected features and AUC0.632+ = 0.87 with interval [0.817;0.906] for four LSW selected features compared to 4D t-SNE mapping (from the original 81D feature space) giving AUC0.632+ = 0.90 with interval [0.847;0.919], all using the MCMC-BANN. Preliminary results appear to indicate capability for the new methods to match or exceed classification performance of current advanced breast lesion CADx algorithms. While not appropriate as a complete replacement of feature selection in CADx problems, DR techniques offer a complementary approach, which can aid elucidation of additional properties associated with the data. Specifically, the new techniques were shown to possess the added benefit of delivering sparse lower dimensional representations for visual interpretation, revealing intricate data structure of the feature space.

Bottom-up attention capture with distractor and target singletons defined in the same (color) dimension is not a matter of feature uncertainty.

PubMed

Weichselbaum, Hanna; Ansorge, Ulrich

2018-05-18

In visual search, attention capture by an irrelevant color-singleton distractor in another feature dimension than the target is dependent on whether or not the distractor changes its feature: Capture is present if the irrelevant color distractor can take on different features across trials, but absent if the distractor takes on only one feature throughout all trials. This influence could be due to down-weighting of the entire color map. Here we tested whether a similar effect could also be brought about by down-weighting of specific color channels within the same maps. We investigated whether a similar dependence of capture on color certainty might hold true if the distractor were defined in the same (color) dimension as the target. At odds with this possibility, in the first and third blocks-in which feature uncertainty was absent-an irrelevant distractor of a certain color captured attention. In addition, in a second block, varying the distractor color created feature uncertainty, but this did not increase capture. Repeating the exact same procedure with the same participants after one week confirmed the stability of the results. The present study showed that a color distractor presented in the same (color) dimension as the target captures attention independent of feature uncertainty. Thus, the down-weighting of single irrelevant color channels within the same feature map used for target search is not a matter of feature uncertainty.

Cognitive Style Mapping at Mt. Hood Community College.

ERIC Educational Resources Information Center

Keyser, John S.

1980-01-01

Describes Mount Hood Community College's experiences using the Modified Hill Model for Cognitive Style Mapping (CSM). Enumerates the nine dimensions of cognitive style assessed by the model. Discusses the value and limitations of CSM, five major checks on the validity of the model, and Mount Hood faculty's involvement with CSM. (AYC)

30 CFR 783.25 - Cross sections, maps, and plans.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) Elevations and locations of monitoring stations used to gather data on water quality and quantity, fish and... aquifers on cross-sections and contour maps; (7) Location of surface water bodies such as streams, lakes... permit area; (9) Location and dimensions of existing areas of spoil, waste, coal development waste, and...

30 CFR 783.25 - Cross sections, maps, and plans.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Elevations and locations of monitoring stations used to gather data on water quality and quantity, fish and... aquifers on cross-sections and contour maps; (7) Location of surface water bodies such as streams, lakes... permit area; (9) Location and dimensions of existing areas of spoil, waste, coal development waste, and...

30 CFR 783.25 - Cross sections, maps, and plans.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Elevations and locations of monitoring stations used to gather data on water quality and quantity, fish and... aquifers on cross-sections and contour maps; (7) Location of surface water bodies such as streams, lakes... permit area; (9) Location and dimensions of existing areas of spoil, waste, coal development waste, and...

30 CFR 783.25 - Cross sections, maps, and plans.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) Elevations and locations of monitoring stations used to gather data on water quality and quantity, fish and... aquifers on cross-sections and contour maps; (7) Location of surface water bodies such as streams, lakes... permit area; (9) Location and dimensions of existing areas of spoil, waste, coal development waste, and...

30 CFR 783.25 - Cross sections, maps, and plans.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) Elevations and locations of monitoring stations used to gather data on water quality and quantity, fish and... aquifers on cross-sections and contour maps; (7) Location of surface water bodies such as streams, lakes... permit area; (9) Location and dimensions of existing areas of spoil, waste, coal development waste, and...

Job Seekers' Perceptions of Teleworking: A Cognitive Mapping Approach.

ERIC Educational Resources Information Center

Kerrin, Maire; Hone, Kate

2001-01-01

College students (n=40) and nonstudent job seekers (n=20) rated four dimensions of telework. Results were plotted in cognitive maps. Students preferred office work to telework, citing lack of social interaction. Nonstudents, slightly older and more likely to be parents, slightly preferred telework. Targeting recruitment to account for these…

Geospatial Technology

ERIC Educational Resources Information Center

Reed, Philip A.; Ritz, John

2004-01-01

Geospatial technology refers to a system that is used to acquire, store, analyze, and output data in two or three dimensions. This data is referenced to the earth by some type of coordinate system, such as a map projection. Geospatial systems include thematic mapping, the Global Positioning System (GPS), remote sensing (RS), telemetry, and…

Beethoven's last piano sonata and those who follow crocodiles: cross-domain mappings of auditory pitch in a musical context.

PubMed

Eitan, Zohar; Timmers, Renee

2010-03-01

Though auditory pitch is customarily mapped in Western cultures onto spatial verticality (high-low), both anthropological reports and cognitive studies suggest that pitch may be mapped onto a wide variety of other domains. We collected a total number of 35 pitch mappings and investigated in four experiments how these mappings are used and structured. In particular, we inquired (1) how Western subjects apply Western and non-Western metaphors to "high" and "low" pitches, (2) whether mappings applied in an abstract conceptual task are similarly applied by listeners to actual music, (3) how mappings of spatial height relate to these pitch mappings, and (4) how mappings of "high" and "low" pitch associate with other dimensions, in particular quantity, size, intensity and valence. The results show strong agreement among Western participants in applying familiar and unfamiliar metaphors for pitch, in both an abstract, conceptual task (Exp. 1) and in a music listening task (Exp. 2), indicating that diverse cross-domain mappings for pitch exist latently besides the common verticality metaphor. Furthermore, limited overlap between mappings of spatial height and pitch height was found, suggesting that, the ubiquity of the verticality metaphor in Western usage notwithstanding, cross-domain pitch mappings are largely independent of that metaphor, and seem to be based upon other underlying dimensions. Part of the discrepancy between spatial height and pitch height is that, for pitch, "up" is not necessarily "more," nor is it necessarily "good." High pitch is only "more" for height, intensity and brightness. It is "less" for mass, size and quantity. We discuss implications of these findings for music and speech prosody, and their relevance to notions of embodied cognition and of cross-domain magnitude representation. Copyright 2009 Elsevier B.V. All rights reserved.

VESGEN Software for Mapping and Quantification of Vascular Regulators

NASA Technical Reports Server (NTRS)

Parsons-Wingerter, Patricia A.; Vickerman, Mary B.; Keith, Patricia A.

2012-01-01

VESsel GENeration (VESGEN) Analysis is an automated software that maps and quantifies effects of vascular regulators on vascular morphology by analyzing important vessel parameters. Quantification parameters include vessel diameter, length, branch points, density, and fractal dimension. For vascular trees, measurements are reported as dependent functions of vessel branching generation. VESGEN maps and quantifies vascular morphological events according to fractal-based vascular branching generation. It also relies on careful imaging of branching and networked vascular form. It was developed as a plug-in for ImageJ (National Institutes of Health, USA). VESGEN uses image-processing concepts of 8-neighbor pixel connectivity, skeleton, and distance map to analyze 2D, black-and-white (binary) images of vascular trees, networks, and tree-network composites. VESGEN maps typically 5 to 12 (or more) generations of vascular branching, starting from a single parent vessel. These generations are tracked and measured for critical vascular parameters that include vessel diameter, length, density and number, and tortuosity per branching generation. The effects of vascular therapeutics and regulators on vascular morphology and branching tested in human clinical or laboratory animal experimental studies are quantified by comparing vascular parameters with control groups. VESGEN provides a user interface to both guide and allow control over the users vascular analysis process. An option is provided to select a morphological tissue type of vascular trees, network or tree-network composites, which determines the general collections of algorithms, intermediate images, and output images and measurements that will be produced.

A real time QRS detection using delay-coordinate mapping for the microcontroller implementation.

PubMed

Lee, Jeong-Whan; Kim, Kyeong-Seop; Lee, Bongsoo; Lee, Byungchae; Lee, Myoung-Ho

2002-01-01

In this article, we propose a new algorithm using the characteristics of reconstructed phase portraits by delay-coordinate mapping utilizing lag rotundity for a real-time detection of QRS complexes in ECG signals. In reconstructing phase portrait the mapping parameters, time delay, and mapping dimension play important roles in shaping of portraits drawn in a new dimensional space. Experimentally, the optimal mapping time delay for detection of QRS complexes turned out to be 20 ms. To explore the meaning of this time delay and the proper mapping dimension, we applied a fill factor, mutual information, and autocorrelation function algorithm that were generally used to analyze the chaotic characteristics of sampled signals. From these results, we could find the fact that the performance of our proposed algorithms relied mainly on the geometrical property such as an area of the reconstructed phase portrait. For the real application, we applied our algorithm for designing a small cardiac event recorder. This system was to record patients' ECG and R-R intervals for 1 h to investigate HRV characteristics of the patients who had vasovagal syncope symptom and for the evaluation, we implemented our algorithm in C language and applied to MIT/BIH arrhythmia database of 48 subjects. Our proposed algorithm achieved a 99.58% detection rate of QRS complexes.

What a Relief: Using Paper Relief Sculpture to Teach Topographic Map Skills

ERIC Educational Resources Information Center

Price, Kelly

2005-01-01

While the struggle persists in science classes to help students visualize in three dimensions, art classes are creating unique sculptures out of paper that produce three-dimensional displays from two-dimensional resources. The translation of paper relief sculpting from the art classroom to the science classroom adds dimension to the teaching of…

Issues Regarding Student Interpretation of Color as a Third Dimension on Graphical Representations

ERIC Educational Resources Information Center

Cid, Ximena C.; Lopez, Ramon E.; Lazarus, Steven M.

2009-01-01

In this study we report on issues related to the use of color as a third dimension on graphical representations provided to students. We find that a majority of the students sampled have a preconceived color map regarding temperature, with blue indicating low temperatures and red indicating high temperatures. Attempts to transfer this particular…

Classifying and quantifying basins of attraction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sprott, J. C.; Xiong, Anda

2015-08-15

A scheme is proposed to classify the basins for attractors of dynamical systems in arbitrary dimensions. There are four basic classes depending on their size and extent, and each class can be further quantified to facilitate comparisons. The calculation uses a Monte Carlo method and is applied to numerous common dissipative chaotic maps and flows in various dimensions.

Pahoehoe toe dimensions, morphology, and branching relationships at Mauna Ulu, Kilauea Volcano, Hawai'i

NASA Astrophysics Data System (ADS)

Crown, David A.; Baloga, Stephen M.

Pahoehoe toe dimensions, morphology, and branching relationships were analyzed in flows emplaced during 1972 at Mauna Ulu, a satellitic shield on the east rift zone of Kilauea Volcano, Hawai'i. In order to characterize regions within flow fields dominated by networks of pahoehoe toes, measurements of toe length, width, thickness, and orientation were completed for 445 toes at 13 sites. Variations in site characteristics, including slope, substrate, and position in the flow field allow an evaluation of the effects of such parameters on toe dimensions. Toe surface morphology (ropy or smooth), local flow lobe position (interior or margin), and connective relationships between toes were documented in the form of detailed toe maps. These maps show the number of branches connecting a given toe to other toes in its local pahoehoe network and illustrate branching patterns. Statistical analyses of toe dimensions and comparisons of pahoehoe toe study sites and sub-populations combined with field observations, evaluation of toe maps, and qualitative examination of toe dimension size distributions show the following: (a) Although there are significant variations at a given site, toes typically have mean lengths (101cm) greater than mean widths (74cm) and mean widths greater than mean thicknesses (19cm) sites that have mean widths greater than mean lengths are those with lower slopes. (b) Where significant site-to-site variations in mean values of a given toe dimension were apparent, these differences could not be directly related to site characteristics. (c) Ropy toes have significantly larger mean values of length, width, and number of branches than smooth toes, and toes with three or more branches have greater lengths, widths, and thicknesses than toes with two or fewer branches, suggesting concentration of flow in these toe types. (d) The skewness of all size distributions of toe length and width to larger values suggests that toes are transitional to larger sheets and channels, consistent with field observations; and (e) Two distinct types of branching patterns (called monolayer and centrally ridged) were observed in preserved pahoehoe flow lobes. The significant variability in measured toe dimensions at Mauna Ulu suggests that toe dimensions are influenced by numerous locally defined, random factors, and that an approach based on stochastic methods can be used to model pahoehoe flow emplacement.

Atomic scale chemical tomography of human bone

NASA Astrophysics Data System (ADS)

Langelier, Brian; Wang, Xiaoyue; Grandfield, Kathryn

2017-01-01

Human bone is a complex hierarchical material. Understanding bone structure and its corresponding composition at the nanometer scale is critical for elucidating mechanisms of biomineralization under healthy and pathological states. However, the three-dimensional structure and chemical nature of bone remains largely unexplored at the nanometer scale due to the challenges associated with characterizing both the structural and chemical integrity of bone simultaneously. Here, we use correlative transmission electron microscopy and atom probe tomography for the first time, to our knowledge, to reveal structures in human bone at the atomic level. This approach provides an overlaying chemical map of the organic and inorganic constituents of bone on its structure. This first use of atom probe tomography on human bone reveals local gradients, trace element detection of Mg, and the co-localization of Na with the inorganic-organic interface of bone mineral and collagen fibrils, suggesting the important role of Na-rich organics in the structural connection between mineral and collagen. Our findings provide the first insights into the hierarchical organization and chemical heterogeneity in human bone in three-dimensions at its smallest length scale - the atomic level. We demonstrate that atom probe tomography shows potential for new insights in biomineralization research on bone.

Mapping a multidimensional emotion in response to television commercials.

PubMed

Morris, Jon D; Klahr, Nelson J; Shen, Feng; Villegas, Jorge; Wright, Paul; He, Guojun; Liu, Yijun

2009-03-01

Unlike previous emotional studies using functional neuroimaging that have focused on either locating discrete emotions in the brain or linking emotional response to an external behavior, this study investigated brain regions in order to validate a three-dimensional construct--namely pleasure, arousal, and dominance (PAD) of emotion induced by marketing communication. Emotional responses to five television commercials were measured with Advertisement Self-Assessment Manikins (AdSAM) for PAD and with functional magnetic resonance imaging (fMRI) to identify corresponding patterns of brain activation. We found significant differences in the AdSAM scores on the pleasure and arousal rating scales among the stimuli. Using the AdSAM response as a model for the fMRI image analysis, we showed bilateral activations in the inferior frontal gyri and middle temporal gyri associated with the difference on the pleasure dimension, and activations in the right superior temporal gyrus and right middle frontal gyrus associated with the difference on the arousal dimension. These findings suggest a dimensional approach of constructing emotional changes in the brain and provide a better understanding of human behavior in response to advertising stimuli.

The National Map: from geography to mapping and back again

USGS Publications Warehouse

Kelmelis, John A.; DeMulder, Mark L.; Ogrosky, Charles E.; Van Driel, J. Nicholas; Ryan, Barbara J.

2003-01-01

When the means of production for national base mapping were capital intensive, required large production facilities, and had ill-defined markets, Federal Government mapping agencies were the primary providers of the spatial data needed for economic development, environmental management, and national defense. With desktop geographic information systems now ubiquitous, source data available as a commodity from private industry, and the realization that many complex problems faced by society need far more and different kinds of spatial data for their solutions, national mapping organizations must realign their business strategies to meet growing demand and anticipate the needs of a rapidly changing geographic information environment. The National Map of the United States builds on a sound historic foundation of describing and monitoring the land surface and adds a focused effort to produce improved understanding, modeling, and prediction of land-surface change. These added dimensions bring to bear a broader spectrum of geographic science to address extant and emerging issues. Within the overarching construct of The National Map, the U.S. Geological Survey (USGS) is making a transition from data collector to guarantor of national data completeness; from producing paper maps to supporting an online, seamless, integrated database; and from simply describing the Nation’s landscape to linking these descriptions with increased scientific understanding. Implementing the full spectrum of geographic science addresses a myriad of public policy issues, including land and natural resource management, recreation, urban growth, human health, and emergency planning, response, and recovery. Neither these issues nor the science and technologies needed to deal with them are static. A robust research agenda is needed to understand these changes and realize The National Map vision. Initial successes have been achieved. These accomplishments demonstrate the utility of The National Map to the Nation and give confidence in evolving its future applications.

Dimensions of Attention Associated With the Microstructure of Corona Radiata White Matter.

PubMed

Stave, Elise A; De Bellis, Michael D; Hooper, Steven R; Woolley, Donald P; Chang, Suk Ki; Chen, Steven D

2017-04-01

Mirsky proposed a model of attention that included these dimensions: focus/execute, sustain, stabilize, encode, and shift. The neural correlates of these dimensions were investigated within corona radiata subregions in healthy youth. Diffusion tensor imaging and neuropsychological assessments were conducted in 79 healthy, right-handed youth aged 4-17 years. Diffusion tensor imaging maps were analyzed using standardized parcellation methods. Partial Pearson correlations between neuropsychological standardized scores, representing these attention dimensions, and diffusion tensor imaging measures of corona radiata subregions were calculated after adjusting for gender and IQ. Significant correlations were found between the focus/execute, sustain, stabilize, and shift dimensions and imaging metrics in hypothesized corona radiata subregions. Results suggest that greater microstructural white matter integrity of the corona radiata is partly associated with attention across 4 attention dimensions. Findings suggest that white matter microstructure of the corona radiata is a neural correlate of several, but not all, attention dimensions.

Dimensions of Attention Associated with the Microstructure of Corona Radiata White Matter

PubMed Central

Stave, Elise A.; Hooper, Stephen R.; Woolley, Donald P.; Chang, Suk Ki; Chen, Steven D.

2016-01-01

Mirsky proposed a model of attention that included these dimensions: focus/execute, sustain, stabilize, encode, and shift. The neural correlates of these dimensions were investigated within corona radiate subregions in healthy youth. Diffusion tensor imaging and neuropsychological assessments were conducted in 79 healthy, right-handed youth aged 4–17 years. Diffusion tensor imaging maps were analyzed using standardized parcellation methods. Partial Pearson correlations between neuropsychological standardized scores, representing these attention dimensions, and diffusion tensor imaging measures of corona radiate subregions were calculated after adjusting for gender and IQ. Significant correlations were found between the focus/execute, sustain, stabilize and shift dimensions and imaging metrics in hypothesized corona radiate subregions. Results suggest that greater microstructural white matter integrity of the corona radiata is partly associated with attention across four attention dimensions. Findings suggest that white matter microstructure of the corona radiata is a neural correlate of several, but not all, attention dimensions. PMID:28090797

[The concept mapping of representations of the future of health services in French in linguistic minority].

PubMed

Bouchard, Louise

2013-06-06

In the context of institutional incompleteness affecting the official minority language communities, we examine how the Francophones in a minority context see the future of health services offered in French. The study is based on a participatory methodology: the concept mapping will serve to identify the conceptual universe of a given problem. From a master statement such as: "When I think about the future of health services in French, I think of ...", participants are invited to make as many statements as come to mind. These statements are then categorized individually and treated collectively through a multivariate analysis. The main themes emerging from the mapping exercise indicate the issues and challenges raised by the participants, namely the geographical context, specific needs, language rights, education and training, human resources, bilingualism and translation, the minority experience, active offer, the role of governmental bodies, community mobilization, collaboration and networking. The participatory approach that concept mapping allows is interesting in more than one way: its flexibility provides a space for both individual and collective reflection; it allows identification and structuring of the crucial dimensions of an issue; and the research outcomes are useful both to researchers and participants in guiding action and achieving goals. Social actors can therefore benefit from a collective dynamic to reflect on the foundations for the development and organization of health services in French.

Magrit: a new thematic cartography tool

NASA Astrophysics Data System (ADS)

Viry, Matthieu; Giraud, Timothée; Lambert, Nicolas

2018-05-01

The article provides an overview of the features of the Magrit web application: a free online thematic mapping tool, presenting a strong pedagogical dimension and making possible to mobilize all the elements necessary for the realization of a thematic map. In this tool, several simple modes of representation are proposed such as proportional maps or choropleth maps. Other, more complex modes are also available such as smoothed maps and cartograms. Each map can be finalized thanks to layout and customization features (projection, scale, orientation, toponyms, etc.) and exported in vector format. Magrit is therefore a complete, light and versatile tool particularly adapted to cartography teaching at the university.

Towards quality criteria for regional public health reporting: concept mapping with Dutch experts.

PubMed

van Bon-Martens, Marja J H; Achterberg, Peter W; van de Goor, Ien A M; van Oers, Hans A M

2012-06-01

In the Netherlands, municipal health assessments are carried out by 28 Regional Health Services, serving 418 municipalities. In the absence of guidelines, regional public health reports were developed in two pilot regions on the basis of the model and experience of national health reporting. Though they were well received and positively evaluated, it was not clear which specific characteristics determined 'good public health reporting'. Therefore, this study was set up to develop a theoretical framework for the quality of regional public health reporting in The Netherlands. Using concept mapping as a standardized tool for conceptualization, 35 relevant reporting experts formulated short statements in two different brainstorming sessions, describing specific quality criteria of regional public health reports. After the removal of duplicates, the list was supplemented with international criteria, and the statements were sent to each participant for rating and sorting. The results were processed statistically and represented graphically. The output was discussed and interpreted, leading to the final concept map. The final concept map consisted of 97 criteria, grouped into 13 clusters, and plotted in two dimensions: a 'product' dimension, ranging from 'production' to 'content', and a 'context' dimension, ranging from 'science' to 'policy'. The three most important clusters were: (i) 'solution orientation', (ii) 'policy relevance' and (iii) 'policy impact'. This study provided a theoretical framework for the quality of regional public health reporting, indicating relevant domains and criteria. Further work should translate domains and criteria into operational indicators for evaluating regional public health reports.

The Human Dimensions of Riparian Areas: Implications for Management and Planning

Treesearch

John F. Dwyer; Pamela J. Jakes; Susan C. Barro

2000-01-01

This chapter introduces an important dimension in building our understanding of how riparian systems function -- people. The human dimensions of natural resource management concerns how people value and interact with these ecosystems, their processes and functions. People as users, managers, owners, or involved citizens are integral components of riparian ecosystems...

World View: The Second Hidden Dimension.

ERIC Educational Resources Information Center

Skow, Lisa; And Others

Proposing that world view is a dimension of culture which lies below the surface of human behavior at the level of the subconscious, this paper argues that this often ignored dimension of culture profoundly influences human communication. The paper is divided into two sections. First, world view is defined and its importance in explaining how…

Fuzzy fractals, chaos, and noise

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zardecki, A.

1997-05-01

To distinguish between chaotic and noisy processes, the authors analyze one- and two-dimensional chaotic mappings, supplemented by the additive noise terms. The predictive power of a fuzzy rule-based system allows one to distinguish ergodic and chaotic time series: in an ergodic series the likelihood of finding large numbers is small compared to the likelihood of finding them in a chaotic series. In the case of two dimensions, they consider the fractal fuzzy sets whose {alpha}-cuts are fractals, arising in the context of a quadratic mapping in the extended complex plane. In an example provided by the Julia set, the conceptmore » of Hausdorff dimension enables one to decide in favor of chaotic or noisy evolution.« less

Structural and functional analyses of human cerebral cortex using a surface-based atlas

NASA Technical Reports Server (NTRS)

Van Essen, D. C.; Drury, H. A.

1997-01-01

We have analyzed the geometry, geography, and functional organization of human cerebral cortex using surface reconstructions and cortical flat maps of the left and right hemispheres generated from a digital atlas (the Visible Man). The total surface area of the reconstructed Visible Man neocortex is 1570 cm2 (both hemispheres), approximately 70% of which is buried in sulci. By linking the Visible Man cerebrum to the Talairach stereotaxic coordinate space, the locations of activation foci reported in neuroimaging studies can be readily visualized in relation to the cortical surface. The associated spatial uncertainty was empirically shown to have a radius in three dimensions of approximately 10 mm. Application of this approach to studies of visual cortex reveals the overall patterns of activation associated with different aspects of visual function and the relationship of these patterns to topographically organized visual areas. Our analysis supports a distinction between an anterior region in ventral occipito-temporal cortex that is selectively involved in form processing and a more posterior region (in or near areas VP and V4v) involved in both form and color processing. Foci associated with motion processing are mainly concentrated in a region along the occipito-temporal junction, the ventral portion of which overlaps with foci also implicated in form processing. Comparisons between flat maps of human and macaque monkey cerebral cortex indicate significant differences as well as many similarities in the relative sizes and positions of cortical regions known or suspected to be homologous in the two species.

The human dimensions of energy use in buildings: A review

DOE Office of Scientific and Technical Information (OSTI.GOV)

D'Oca, Simona; Hong, Tianzhen; Langevin, Jared

The “human dimensions” of energy use in buildings refer to the energy-related behaviors of key stakeholders that affect energy use over the building life cycle. Stakeholders include building designers, operators, managers, engineers, occupants, industry, vendors, and policymakers, who directly or indirectly influence the acts of designing, constructing, living, operating, managing, and regulating the built environments, from individual building up to the urban scale. Among factors driving high-performance buildings, human dimensions play a role that is as significant as that of technological advances. However, this factor is not well understood, and, as a result, human dimensions are often ignored or simplifiedmore » by stakeholders. This work presents a review of the literature on human dimensions of building energy use to assess the state-of-the-art in this topic area. The paper highlights research needs for fully integrating human dimensions into the building design and operation processes with the goal of reducing energy use in buildings while enhancing occupant comfort and productivity. This research focuses on identifying key needs for each stakeholder involved in a building's life cycle and takes an interdisciplinary focus that spans the fields of architecture and engineering design, sociology, data science, energy policy, codes, and standards to provide targeted insights. Greater understanding of the human dimensions of energy use has several potential benefits including reductions in operating cost for building owners; enhanced comfort conditions and productivity for building occupants; more effective building energy management and automation systems for building operators and energy managers; and the integration of more accurate control logic into the next generation of human-in-the-loop technologies. The review concludes by summarizing recommendations for policy makers and industry stakeholders for developing codes, standards, and technologies that can leverage the human dimensions of energy use to reliably predict and achieve energy use reductions in the residential and commercial buildings sectors.« less

The human dimensions of energy use in buildings: A review

DOE PAGES

D'Oca, Simona; Hong, Tianzhen; Langevin, Jared

2017-08-19

The “human dimensions” of energy use in buildings refer to the energy-related behaviors of key stakeholders that affect energy use over the building life cycle. Stakeholders include building designers, operators, managers, engineers, occupants, industry, vendors, and policymakers, who directly or indirectly influence the acts of designing, constructing, living, operating, managing, and regulating the built environments, from individual building up to the urban scale. Among factors driving high-performance buildings, human dimensions play a role that is as significant as that of technological advances. However, this factor is not well understood, and, as a result, human dimensions are often ignored or simplifiedmore » by stakeholders. This work presents a review of the literature on human dimensions of building energy use to assess the state-of-the-art in this topic area. The paper highlights research needs for fully integrating human dimensions into the building design and operation processes with the goal of reducing energy use in buildings while enhancing occupant comfort and productivity. This research focuses on identifying key needs for each stakeholder involved in a building's life cycle and takes an interdisciplinary focus that spans the fields of architecture and engineering design, sociology, data science, energy policy, codes, and standards to provide targeted insights. Greater understanding of the human dimensions of energy use has several potential benefits including reductions in operating cost for building owners; enhanced comfort conditions and productivity for building occupants; more effective building energy management and automation systems for building operators and energy managers; and the integration of more accurate control logic into the next generation of human-in-the-loop technologies. The review concludes by summarizing recommendations for policy makers and industry stakeholders for developing codes, standards, and technologies that can leverage the human dimensions of energy use to reliably predict and achieve energy use reductions in the residential and commercial buildings sectors.« less

Invasion Percolation and Global Optimization

NASA Astrophysics Data System (ADS)

Barabási, Albert-László

1996-05-01

Invasion bond percolation (IBP) is mapped exactly into Prim's algorithm for finding the shortest spanning tree of a weighted random graph. Exploring this mapping, which is valid for arbitrary dimensions and lattices, we introduce a new IBP model that belongs to the same universality class as IBP and generates the minimal energy tree spanning the IBP cluster.

Computer Games versus Maps before Reading Stories: Priming Readers' Spatial Situation Models

ERIC Educational Resources Information Center

Smith, Glenn Gordon; Majchrzak, Dan; Hayes, Shelley; Drobisz, Jack

2011-01-01

The current study investigated how computer games and maps compare as preparation for readers to comprehend and retain spatial relations in text narratives. Readers create situation models of five dimensions: spatial, temporal, causal, goal, and protagonist (Zwaan, Langston, & Graesser 1995). Of these five, readers mentally model the spatial…

Special ergodic theorems and dynamical large deviations

NASA Astrophysics Data System (ADS)

Kleptsyn, Victor; Ryzhov, Dmitry; Minkov, Stanislav

2012-11-01

Let f : M → M be a self-map of a compact Riemannian manifold M, admitting a global SRB measure μ. For a continuous test function \\varphi\\colon M\\to R and a constant α > 0, consider the set Kφ,α of the initial points for which the Birkhoff time averages of the function φ differ from its μ-space average by at least α. As the measure μ is a global SRB one, the set Kφ,α should have zero Lebesgue measure. The special ergodic theorem, whenever it holds, claims that, moreover, this set has a Hausdorff dimension less than the dimension of M. We prove that for Lipschitz maps, the special ergodic theorem follows from the dynamical large deviations principle. We also define and prove analogous result for flows. Applying the theorems of Young and of Araújo and Pacifico, we conclude that the special ergodic theorem holds for transitive hyperbolic attractors of C2-diffeomorphisms, as well as for some other known classes of maps (including the one of partially hyperbolic non-uniformly expanding maps) and flows.

Contrasting vertical and horizontal representations of affect in emotional visual search.

PubMed

Damjanovic, Ljubica; Santiago, Julio

2016-02-01

Independent lines of evidence suggest that the representation of emotional evaluation recruits both vertical and horizontal spatial mappings. These two spatial mappings differ in their experiential origins and their productivity, and available data suggest that they differ in their saliency. Yet, no study has so far compared their relative strength in an attentional orienting reaction time task that affords the simultaneous manifestation of both types of mapping. Here, we investigated this question using a visual search task with emotional faces. We presented angry and happy face targets and neutral distracter faces in top, bottom, left, and right locations on the computer screen. Conceptual congruency effects were observed along the vertical dimension supporting the 'up = good' metaphor, but not along the horizontal dimension. This asymmetrical processing pattern was observed when faces were presented in a cropped (Experiment 1) and whole (Experiment 2) format. These findings suggest that the 'up = good' metaphor is more salient and readily activated than the 'right = good' metaphor, and that the former outcompetes the latter when the task context affords the simultaneous activation of both mappings.

viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia.

PubMed

Amir, El-ad David; Davis, Kara L; Tadmor, Michelle D; Simonds, Erin F; Levine, Jacob H; Bendall, Sean C; Shenfeld, Daniel K; Krishnaswamy, Smita; Nolan, Garry P; Pe'er, Dana

2013-06-01

New high-dimensional, single-cell technologies offer unprecedented resolution in the analysis of heterogeneous tissues. However, because these technologies can measure dozens of parameters simultaneously in individual cells, data interpretation can be challenging. Here we present viSNE, a tool that allows one to map high-dimensional cytometry data onto two dimensions, yet conserve the high-dimensional structure of the data. viSNE plots individual cells in a visual similar to a scatter plot, while using all pairwise distances in high dimension to determine each cell's location in the plot. We integrated mass cytometry with viSNE to map healthy and cancerous bone marrow samples. Healthy bone marrow automatically maps into a consistent shape, whereas leukemia samples map into malformed shapes that are distinct from healthy bone marrow and from each other. We also use viSNE and mass cytometry to compare leukemia diagnosis and relapse samples, and to identify a rare leukemia population reminiscent of minimal residual disease. viSNE can be applied to any multi-dimensional single-cell technology.

phylogeo: an R package for geographic analysis and visualization of microbiome data.

PubMed

Charlop-Powers, Zachary; Brady, Sean F

2015-09-01

We have created an R package named phylogeo that provides a set of geographic utilities for sequencing-based microbial ecology studies. Although the geographic location of samples is an important aspect of environmental microbiology, none of the major software packages used in processing microbiome data include utilities that allow users to map and explore the spatial dimension of their data. phylogeo solves this problem by providing a set of plotting and mapping functions that can be used to visualize the geographic distribution of samples, to look at the relatedness of microbiomes using ecological distance, and to map the geographic distribution of particular sequences. By extending the popular phyloseq package and using the same data structures and command formats, phylogeo allows users to easily map and explore the geographic dimensions of their data from the R programming language. phylogeo is documented and freely available http://zachcp.github.io/phylogeo : zcharlop@rockefeller.edu. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Anthropometry of the proximal tibia of patients with knee arthritis in Shanghai.

PubMed

Liu, Zhihong; Yuan, Gaoxiang; Zhang, Weibin; Shen, Yuhui; Deng, Lianfu

2013-05-01

We measured the resected bony surface of the proximal tibia from reconstructed 3D models of the 179 arthritis knees using CT data. We found that the mediolateral (ML) dimension (69.6 ± 9.2 mm) and anteroposterior (AP) dimension (46.1 ± 6.1 mm) were less than those of Westerners. It was observed the medial anteroposterior (MAP) dimension (47.1 ± 7.2 mm) was much larger and closer to middle point of ML dimension than lateral anteroposterior (LAP) dimension (42.9 ± 6.3 mm). The aspect ratio (AR) (1.5 ± 0.07) was constant in Shanghai population. Only half of the prostheses we used in clinic mostly matched the resected bony surface of Shanghai population very well in ML, AP and AR dimension. Copyright © 2013 Elsevier Inc. All rights reserved.

Influence on Simon and SNARC Effects of a Nonspatial Stimulus-Response Mapping: Between-Task Logical Recoding

ERIC Educational Resources Information Center

Treccani, Barbara; Milanese, Nadia; Umilta, Carlo

2010-01-01

In 4 experiments, we intermixed trials in which the stimulus color was relevant with trials where participants had to judge the stimulus shape or parity and found that the logical-recoding rule (Hedge & Marsh, 1975) applied to the relevant dimension in a task can generalize to the irrelevant dimension of the other task. The mapping…

Learning redundant motor tasks with and without overlapping dimensions: facilitation and interference effects.

PubMed

Ranganathan, Rajiv; Wieser, Jon; Mosier, Kristine M; Mussa-Ivaldi, Ferdinando A; Scheidt, Robert A

2014-06-11

Prior learning of a motor skill creates motor memories that can facilitate or interfere with learning of new, but related, motor skills. One hypothesis of motor learning posits that for a sensorimotor task with redundant degrees of freedom, the nervous system learns the geometric structure of the task and improves performance by selectively operating within that task space. We tested this hypothesis by examining if transfer of learning between two tasks depends on shared dimensionality between their respective task spaces. Human participants wore a data glove and learned to manipulate a computer cursor by moving their fingers. Separate groups of participants learned two tasks: a prior task that was unique to each group and a criterion task that was common to all groups. We manipulated the mapping between finger motions and cursor positions in the prior task to define task spaces that either shared or did not share the task space dimensions (x-y axes) of the criterion task. We found that if the prior task shared task dimensions with the criterion task, there was an initial facilitation in criterion task performance. However, if the prior task did not share task dimensions with the criterion task, there was prolonged interference in learning the criterion task due to participants finding inefficient task solutions. These results show that the nervous system learns the task space through practice, and that the degree of shared task space dimensionality influences the extent to which prior experience transfers to subsequent learning of related motor skills. Copyright © 2014 the authors 0270-6474/14/348289-11$15.00/0.

Planning for the Human Dimensions of Oil Spills and Spill Response

NASA Astrophysics Data System (ADS)

Webler, Thomas; Lord, Fabienne

2010-04-01

Oil spill contingency planners need an improved approach to understanding and planning for the human dimensions of oil spills. Drawing on existing literature in social impact assessment, natural hazards, human ecology, adaptive management, global change and sustainability, we develop an integrative approach to understanding and portraying the human dimensions impacts of stressors associated with oil spill events. Our approach is based on three fundamental conclusions that are drawn from this literature review. First, it is productive to acknowledge that, while stressors can produce human impacts directly, they mainly affect intermediary processes and changes to these processes produce human impacts. Second, causal chain modeling taken from hazard management literature provides a means to document how oil spill stressors change processes and produce human impacts. Third, concepts from the global change literature on vulnerability enrich causal models in ways that make more obvious how management interventions lessen hazards and mitigate associated harm. Using examples from recent spill events, we illustrate how these conclusions can be used to diagrammatically portray the human dimensions of oil spills.

Fusion of High Resolution Multispectral Imagery in Vulnerable Coastal and Land Ecosystems.

PubMed

Ibarrola-Ulzurrun, Edurne; Gonzalo-Martin, Consuelo; Marcello-Ruiz, Javier; Garcia-Pedrero, Angel; Rodriguez-Esparragon, Dionisio

2017-01-25

Ecosystems provide a wide variety of useful resources that enhance human welfare, but these resources are declining due to climate change and anthropogenic pressure. In this work, three vulnerable ecosystems, including shrublands, coastal areas with dunes systems and areas of shallow water, are studied. As far as these resources' reduction is concerned, remote sensing and image processing techniques could contribute to the management of these natural resources in a practical and cost-effective way, although some improvements are needed for obtaining a higher quality of the information available. An important quality improvement is the fusion at the pixel level. Hence, the objective of this work is to assess which pansharpening technique provides the best fused image for the different types of ecosystems. After a preliminary evaluation of twelve classic and novel fusion algorithms, a total of four pansharpening algorithms was analyzed using six quality indices. The quality assessment was implemented not only for the whole set of multispectral bands, but also for the subset of spectral bands covered by the wavelength range of the panchromatic image and outside of it. A better quality result is observed in the fused image using only the bands covered by the panchromatic band range. It is important to highlight the use of these techniques not only in land and urban areas, but a novel analysis in areas of shallow water ecosystems. Although the algorithms do not show a high difference in land and coastal areas, coastal ecosystems require simpler algorithms, such as fast intensity hue saturation, whereas more heterogeneous ecosystems need advanced algorithms, as weighted wavelet ' à trous ' through fractal dimension maps for shrublands and mixed ecosystems. Moreover, quality map analysis was carried out in order to study the fusion result in each band at the local level. Finally, to demonstrate the performance of these pansharpening techniques, advanced Object-Based (OBIA) support vector machine classification was applied, and a thematic map for the shrubland ecosystem was obtained, which corroborates wavelet ' à trous ' through fractal dimension maps as the best fusion algorithm for this ecosystem.

Fusion of High Resolution Multispectral Imagery in Vulnerable Coastal and Land Ecosystems

PubMed Central

Ibarrola-Ulzurrun, Edurne; Gonzalo-Martin, Consuelo; Marcello-Ruiz, Javier; Garcia-Pedrero, Angel; Rodriguez-Esparragon, Dionisio

2017-01-01

Ecosystems provide a wide variety of useful resources that enhance human welfare, but these resources are declining due to climate change and anthropogenic pressure. In this work, three vulnerable ecosystems, including shrublands, coastal areas with dunes systems and areas of shallow water, are studied. As far as these resources’ reduction is concerned, remote sensing and image processing techniques could contribute to the management of these natural resources in a practical and cost-effective way, although some improvements are needed for obtaining a higher quality of the information available. An important quality improvement is the fusion at the pixel level. Hence, the objective of this work is to assess which pansharpening technique provides the best fused image for the different types of ecosystems. After a preliminary evaluation of twelve classic and novel fusion algorithms, a total of four pansharpening algorithms was analyzed using six quality indices. The quality assessment was implemented not only for the whole set of multispectral bands, but also for the subset of spectral bands covered by the wavelength range of the panchromatic image and outside of it. A better quality result is observed in the fused image using only the bands covered by the panchromatic band range. It is important to highlight the use of these techniques not only in land and urban areas, but a novel analysis in areas of shallow water ecosystems. Although the algorithms do not show a high difference in land and coastal areas, coastal ecosystems require simpler algorithms, such as fast intensity hue saturation, whereas more heterogeneous ecosystems need advanced algorithms, as weighted wavelet ‘à trous’ through fractal dimension maps for shrublands and mixed ecosystems. Moreover, quality map analysis was carried out in order to study the fusion result in each band at the local level. Finally, to demonstrate the performance of these pansharpening techniques, advanced Object-Based (OBIA) support vector machine classification was applied, and a thematic map for the shrubland ecosystem was obtained, which corroborates wavelet ‘à trous’ through fractal dimension maps as the best fusion algorithm for this ecosystem. PMID:28125055

Dimensions of the scala tympani in the human and cat with reference to cochlear implants.

PubMed

Hatsushika, S; Shepherd, R K; Tong, Y C; Clark, G M; Funasaka, S

1990-11-01

The width, height, and cross-sectional area of the scala tympani in both the human and cat were measured to provide dimensional information relevant to the design of scala tympani electrode arrays. Both the height and width of the human scala tympani decreased rapidly within the first 1.5 mm from the round window. Thereafter, they exhibit a gradual reduction in their dimension with increasing distance from the round window. The cross-sectional area of the human scala tympani reflects the changes observed in both the height and width. In contrast, the cat scala tympani exhibits a rapid decrease in its dimensions over the first 6 to 8 mm from the round window. However, beyond this point the cat scala tympani also exhibits a more gradual decrease in its dimensions. Finally, the width of the scala tympani, in both human and cat, is consistently greater than the height.

A multifractal analysis of equilibrium measures for conformal expanding maps and Moran-like geometric constructions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pesin, Y.; Weiss, H.

1997-01-01

In this paper we establish the complete multifractal formalism for equilibrium measures for Holder continuous conformal expanding maps and expanding Markov Moran-like geometric constructions. Examples include Markov maps of an interval, beta transformations of an interval, rational maps with hyperbolic Julia sets, and conformal total endomorphisms. We also construct a Holder continuous homeomorphism of a compact metric space with an ergodic invariant measure of positive entropy for which the dimension spectrum is not convex, and hence the multifractal formalism fails.

Cognitive mapping in mental time travel and mental space navigation.

PubMed

Gauthier, Baptiste; van Wassenhove, Virginie

2016-09-01

The ability to imagine ourselves in the past, in the future or in different spatial locations suggests that the brain can generate cognitive maps that are independent of the experiential self in the here and now. Using three experiments, we asked to which extent Mental Time Travel (MTT; imagining the self in time) and Mental Space Navigation (MSN; imagining the self in space) shared similar cognitive operations. For this, participants judged the ordinality of real historical events in time and in space with respect to different mental perspectives: for instance, participants mentally projected themselves in Paris in nine years, and judged whether an event occurred before or after, or, east or west, of where they mentally stood. In all three experiments, symbolic distance effects in time and space dimensions were quantified using Reaction Times (RT) and Error Rates (ER). When self-projected, participants were slower and were less accurate (absolute distance effects); participants were also faster and more accurate when the spatial and temporal distances were further away from their mental viewpoint (relative distance effects). These effects show that MTT and MSN require egocentric mapping and that self-projection requires map transformations. Additionally, participants' performance was affected when self-projection was made in one dimension but judgements in another, revealing a competition between temporal and spatial mapping (Experiment 2 & 3). Altogether, our findings suggest that MTT and MSN are separately mapped although they require comparable allo- to ego-centric map conversion. Copyright © 2016 Elsevier B.V. All rights reserved.

Entanglement entropy of dispersive media from thermodynamic entropy in one higher dimension.

PubMed

Maghrebi, M F; Reid, M T H

2015-04-17

A dispersive medium becomes entangled with zero-point fluctuations in the vacuum. We consider an arbitrary array of material bodies weakly interacting with a quantum field and compute the quantum mutual information between them. It is shown that the mutual information in D dimensions can be mapped to classical thermodynamic entropy in D+1 dimensions. As a specific example, we compute the mutual information both analytically and numerically for a range of separation distances between two bodies in D=2 dimensions and find a logarithmic correction to the area law at short separations. A key advantage of our method is that it allows the strong subadditivity property to be easily verified.

The Lyapunov dimension and its estimation via the Leonov method

NASA Astrophysics Data System (ADS)

Kuznetsov, N. V.

2016-06-01

Along with widely used numerical methods for estimating and computing the Lyapunov dimension there is an effective analytical approach, proposed by G.A. Leonov in 1991. The Leonov method is based on the direct Lyapunov method with special Lyapunov-like functions. The advantage of the method is that it allows one to estimate the Lyapunov dimension of invariant sets without localization of the set in the phase space and, in many cases, to get effectively an exact Lyapunov dimension formula. In this work the invariance of the Lyapunov dimension with respect to diffeomorphisms and its connection with the Leonov method are discussed. For discrete-time dynamical systems an analog of Leonov method is suggested. In a simple but rigorous way, here it is presented the connection between the Leonov method and the key related works: Kaplan and Yorke (the concept of the Lyapunov dimension, 1979), Douady and Oesterlé (upper bounds of the Hausdorff dimension via the Lyapunov dimension of maps, 1980), Constantin, Eden, Foiaş, and Temam (upper bounds of the Hausdorff dimension via the Lyapunov exponents and Lyapunov dimension of dynamical systems, 1985-90), and the numerical calculation of the Lyapunov exponents and dimension.

New Visual Methods for Teaching Intersectionality from a Spatial Perspective in a Geography and Gender Course

ERIC Educational Resources Information Center

Baylina Ferré, Mireia; Rodó de Zárate, Maria

2016-01-01

Intersectionality is a complex concept to deal with when doing research but also when teaching the interrelationships between space and social relations. Here we present "Relief Maps" as a visual tool for teaching intersectionality and its spatial dimension in higher education courses. "Relief Maps" are a model developed for…

Mapping the Rural Adolescent Girls' Participation in Residential Non-Formal Education Program--A Study in Lunkaransar Block, Rajasthan, India

ERIC Educational Resources Information Center

Sharma, Shilpa

2002-01-01

The present study, "Mapping Rural Adolescent Girl's Participation in Residential Non- Formal Education Program--A Study in Lunkaransar Block, Rajasthan", was an attempt to understand the dimensions of rural adolescent girls' participation in the "Balika Shivir" Program. It is a six month residential non-formal education program…

"A" Is for Aerial Maps and Art

ERIC Educational Resources Information Center

Todd, Reese H.; Delahunty, Tina

2007-01-01

The technology of satellite imagery and remote sensing adds a new dimension to teaching and learning about maps with elementary school children. Just a click of the mouse brings into view some images of the world that could only be imagined a generation ago. Close-up aerial pictures of the school and neighborhood quickly catch the interest of…

Human Dimensions in Future Battle Command Systems: A Workshop Report

DTIC Science & Technology

2008-04-01

information processing). These dimensions can best be described anecdotally and metaphorically as: • Battle command is a human-centric...enhance information visualization techniques in the decision tools, including multimodal platforms: video, graphics, symbols, etc. This should be...organization members. Each dimension can metaphorically represent the spatial location of individuals and group thinking in a trajectory of social norms

Fifth dimension of life and the 4/5 allometric scaling law for human brain.

PubMed

He, Ji-Huan; Zhang, Juan

2004-01-01

Brain cells are not spherical. The basal metabolic rate (B) of a spherical cell scales as B approximately r2, where r is the radius of the cell; that of a brain cell scales as B approximately r(d), where r is the characteristic radius of the cell and d is the fractal dimensionality of its contour. The fractal geometry of the cell leads to a 4/5 allometric scaling law for human brain, uniquely endowing humans with a 5th dimension and successfully explains why the scaling exponent varies during rest and exercise. A striking analogy between Kleiber's 3/4 law and Newton's second law is heuristically illustrated. A physical explanation is given for the 4th dimension of life for three-dimensional organisms and the 5th dimension for human brain.

Magnetic resonance spectroscopy of the human brain.

PubMed

Ross, B; Bluml, S

2001-04-01

Magnetic resonance (MR; synonymous with NMR = nuclear magnetic resonance) is a universal physical technique best known for non-invasive detection and anatomical mapping of water protons (H). MR-spectroscopy (MRS) records protons from tissue chemicals other than water, intrinsic phosphorus containing metabolites, sodium, potassium, carbon, nitrogen, and fluorine. MRS is therefore an imaging technique with the potential to record human and animal biochemistry in vivo. As a result of wide availability of MRI equipment in research laboratories and hospitals, MRS is a serious competitor with PET to define normal body composition and its perturbation by pharmacological and pathological events. This article describes practical aspects of in vivo MRS with particular emphasis on the brain, where novel metabolites have been described. A survey of these new aspects of neurochemistry emphasize their practical utility as neuronal and axonal markers, measures of energy status, membrane constituents, and osmolytes, as well as some xenobiotics, such as alcohol. The concept of multinuclear in vivo MRS is illustrated by diagnosis and therapeutic monitoring of several human brain disorders. Although these methods are currently most frequently encountered in human studies, as well as with transgenic and knockout mouse models, MRS adds a new dimension to anatomic and histopathologic descriptions. Copyright 2001 Wiley-Liss, Inc.

Evaluating patient and public involvement in health research: from theoretical model to practical workshop.

PubMed

Gibson, Andy; Welsman, Jo; Britten, Nicky

2017-10-01

There is a growing literature on evaluating aspects of patient and public involvement (PPI). We have suggested that at the core of successful PPI is the dynamic interaction of different forms of knowledge, notably lay and professional. We have developed a four-dimensional theoretical framework for understanding these interactions. We explore the practical utility of the theoretical framework as a tool for mapping and evaluating the experience of PPI in health services research. We conducted three workshops with different PPI groups in which participants were invited to map their PPI experiences on wall charts representing the four dimensions of our framework. The language used to describe the four dimensions was modified to make it more accessible to lay audiences. Participants were given sticky notes to indicate their own positions on the different dimensions and to write explanatory comments if they wished. Participants' responses were then discussed and analysed as a group. The three groups were distinctive in their mapped responses suggesting different experiences in relation to having a strong or weak voice in their organization, having few or many ways of getting involved, addressing organizational or public concerns and believing that the organization was willing to change or not. The framework has practical utility for mapping and evaluating PPI interactions and is sensitive to differences in PPI experiences within and between different organizations. The workshops enabled participants to reflect collaboratively on their experiences with a view to improving PPI experiences and planning for the future. © 2017 The Authors Health Expectations published by John Wiley & Sons Ltd.

Bifurcations of periodic motion in a three-degree-of-freedom vibro-impact system with clearance

NASA Astrophysics Data System (ADS)

Liu, Yongbao; Wang, Qiang; Xu, Huidong

2017-07-01

The smooth bifurcation and grazing non-smooth bifurcation of periodic motion of a three-degree-of-freedom vibro-impact system with clearance are studied in this paper. Firstly, a periodic solution of vibro-impact system is solved and a six-dimensional Poincaré map is established. Then, for the six-dimensional Poincaré map, the analytic expressions of all eigenvalues of Jacobi matrix with respect to parameters are unavailable. This implies that with application of the classical critical criterion described by the properties of eigenvalues, we have to numerically compute eigenvalues point by point and check their properties to search for the bifurcation points. Such the numerical calculation is a laborious job in the process of determining bifurcation points. To overcome the difficulty that originates from the classical bifurcation criteria, the explicit critical criteria without using eigenvalues calculation of high-dimensional map are applied to determine bifurcation points of Co-dimension-one period doubling bifurcation and Co-dimension-one Neimark-Sacker bifurcation and Co-dimension-two Flip-Neimark-Sacker bifurcation, and then local dynamical behaviors of these bifurcations are analyzed. Moreover, the directions of period doubling bifurcation and Neimark-Sacker bifurcation are analyzed by center manifold reduction theory and normal form approach. Finally, the existence of the grazing periodic motion of the vibro-impact system is analyzed and the grazing bifurcation point is obtained, the discontinuous grazing bifurcation behavior is studied based on the compound normal form map near the grazing point, the discontinuous jumping phenomenon and co-existing multiple solutions near the grazing bifurcation point are revealed.

QSL Squasher: A Fast Quasi-separatrix Layer Map Calculator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tassev, Svetlin; Savcheva, Antonia, E-mail: svetlin.tassev@cfa.harvard.edu

Quasi-Separatrix Layers (QSLs) are a useful proxy for the locations where current sheets can develop in the solar corona, and give valuable information about the connectivity in complicated magnetic field configurations. However, calculating QSL maps, even for two-dimensional slices through three-dimensional models of coronal magnetic fields, is a non-trivial task, as it usually involves tracing out millions of magnetic field lines with immense precision. Thus, extending QSL calculations to three dimensions has rarely been done until now. In order to address this challenge, we present QSL Squasher—a public, open-source code, which is optimized for calculating QSL maps in both twomore » and three dimensions on graphics processing units. The code achieves large processing speeds for three reasons, each of which results in an order-of-magnitude speed-up. (1) The code is parallelized using OpenCL. (2) The precision requirements for the QSL calculation are drastically reduced by using perturbation theory. (3) A new boundary detection criterion between quasi-connectivity domains is used, which quickly identifies possible QSL locations that need to be finely sampled by the code. That boundary detection criterion relies on finding the locations of abrupt field-line length changes, which we do by introducing a new Field-line Length Edge (FLEDGE) map. We find FLEDGE maps useful on their own as a quick-and-dirty substitute for QSL maps. QSL Squasher allows construction of high-resolution 3D FLEDGE maps in a matter of minutes, which is two orders of magnitude faster than calculating the corresponding 3D QSL maps. We include a sample of calculations done using QSL Squasher to demonstrate its capabilities as a QSL calculator, as well as to compare QSL and FLEDGE maps.« less

QSL Squasher: A Fast Quasi-separatrix Layer Map Calculator

NASA Astrophysics Data System (ADS)

Tassev, Svetlin; Savcheva, Antonia

2017-05-01

Quasi-Separatrix Layers (QSLs) are a useful proxy for the locations where current sheets can develop in the solar corona, and give valuable information about the connectivity in complicated magnetic field configurations. However, calculating QSL maps, even for two-dimensional slices through three-dimensional models of coronal magnetic fields, is a non-trivial task, as it usually involves tracing out millions of magnetic field lines with immense precision. Thus, extending QSL calculations to three dimensions has rarely been done until now. In order to address this challenge, we present QSL Squasher—a public, open-source code, which is optimized for calculating QSL maps in both two and three dimensions on graphics processing units. The code achieves large processing speeds for three reasons, each of which results in an order-of-magnitude speed-up. (1) The code is parallelized using OpenCL. (2) The precision requirements for the QSL calculation are drastically reduced by using perturbation theory. (3) A new boundary detection criterion between quasi-connectivity domains is used, which quickly identifies possible QSL locations that need to be finely sampled by the code. That boundary detection criterion relies on finding the locations of abrupt field-line length changes, which we do by introducing a new Field-line Length Edge (FLEDGE) map. We find FLEDGE maps useful on their own as a quick-and-dirty substitute for QSL maps. QSL Squasher allows construction of high-resolution 3D FLEDGE maps in a matter of minutes, which is two orders of magnitude faster than calculating the corresponding 3D QSL maps. We include a sample of calculations done using QSL Squasher to demonstrate its capabilities as a QSL calculator, as well as to compare QSL and FLEDGE maps.

Building perceptual color maps for visualizing interval data

NASA Astrophysics Data System (ADS)

Kalvin, Alan D.; Rogowitz, Bernice E.; Pelah, Adar; Cohen, Aron

2000-06-01

In visualization, a 'color map' maps a range of data values onto a scale of colors. However, unless a color map is e carefully constructed, visual artifacts can be produced. This problem has stimulated considerable interest in creating perceptually based color maps, that is, color maps where equal steps in data value are perceived as equal steps in the color map [Robertson (1988); Pizer (1981); Green (1992); Lefkowitz and Herman, 1992)]. In Rogowitz and Treinish, (1996, 1998) and in Bergman, Treinish and Rogowitz, (1995), we demonstrated that color maps based on luminance or saturation could be good candidates for satisfying this requirement. This work is based on the seminal work of S.S. Stevens (1966), who measured the perceived magnitude of different magnitudes of physical stimuli. He found that for many physical scales, including luminance (cd/m2) and saturation (the 'redness' of a long-wavelength light source), equal ratios in stimulus value produced equal ratios in perceptual magnitude. He interpreted this as indicating that there exists in human cognition a common scale for representing magnitude, and we scale the effects of different physical stimuli to this internal scale. In Rogowitz, Kalvin, Pelahb and Cohen (1999), we used a psychophysical technique to test this hypothesis as it applies to the creation of perceptually uniform color maps. We constructed color maps as trajectories through three-color spaces, a common computer graphics standard (uncalibrated HSV), a common perceptually-based engineering standard for creating visual stimuli (L*a*b*), and a space commonly used in the graphic arts (Munsell). For each space, we created color scales that varied linearly in hue, saturation, or luminance and measured the detectability of increments in hue, saturation or luminance for each of these color scales. We measured the amplitude of the just-detectable Gaussian increments at 20 different values along the range of each color map. For all three color spaces, we found that luminance-based color maps provided the most perceptually- uniform representations of the data. The just-detectable increment was constant at all points in the color map, with the exception of the lowest-luminance values, where a larger increment was required. The saturation-based color maps provided less sensitivity than the luminance-based color maps, requiring much larger increments for detection. For the hue- based color maps, the size of the increment required for detection varied across the range. For example, for the standard 'rainbow' color map (uncalibrated HSV, hue-varying map), a step in the 'green' region required an increment 16 times the size of the increment required in the 'cyan' part of the range. That is, the rainbow color map would not successfully represent changes in the data in the 'green' region of this color map. In this paper, we extend this research by studying the detectability of spatially-modulated Gabor targets based on these hue, saturation and luminance scales. Since, in visualization, the user is called upon to detect and identify patterns that vary in their spatial characteristics, it is important to study how different types of color maps represent data with varying spatial properties. To do so, we measured modulation thresholds for low-(0.2 c/deg) and high-spatial frequency (4.0 c/deg) Gabor patches and compared them with the Gaussian results. As before, we measured increment thresholds for hue, saturation, and luminance modulations. These color scales were constructed as trajectories along the three perceptual dimensions of color (hue, saturation, and luminance) in two color spaces, uncalibrated HSV and calibrated L*a*b. This allowed us to study how the three perceptual dimensions represent magnitude information for test patterns varying in spatial frequency. This design also allowed us to test the hypothesis that the luminance channel best carries high-spatial frequency information while the saturation channel best represents low spatial-frequency information (Mullen 1985; DeValois and DeValois 1988).

A 1463 Gene Cattle–Human Comparative Map With Anchor Points Defined by Human Genome Sequence Coordinates

PubMed Central

Everts-van der Wind, Annelie; Kata, Srinivas R.; Band, Mark R.; Rebeiz, Mark; Larkin, Denis M.; Everts, Robin E.; Green, Cheryl A.; Liu, Lei; Natarajan, Shreedhar; Goldammer, Tom; Lee, Jun Heon; McKay, Stephanie; Womack, James E.; Lewin, Harris A.

2004-01-01

A second-generation 5000 rad radiation hybrid (RH) map of the cattle genome was constructed primarily using cattle ESTs that were targeted to gaps in the existing cattle–human comparative map, as well as to sparsely populated map intervals. A total of 870 targeted markers were added, bringing the number of markers mapped on the RH5000 panel to 1913. Of these, 1463 have significant BLASTN hits (E < e–5) against the human genome sequence. A cattle–human comparative map was created using human genome sequence coordinates of the paired orthologs. One-hundred and ninety-five conserved segments (defined by two or more genes) were identified between the cattle and human genomes, of which 31 are newly discovered and 34 were extended singletons on the first-generation map. The new map represents an improvement of 20% genome-wide comparative coverage compared with the first-generation map. Analysis of gene content within human genome regions where there are gaps in the comparative map revealed gaps with both significantly greater and significantly lower gene content. The new, more detailed cattle–human comparative map provides an improved resource for the analysis of mammalian chromosome evolution, the identification of candidate genes for economically important traits, and for proper alignment of sequence contigs on cattle chromosomes. PMID:15231756

A comprehensive mapping of the current capacity for human nutrition training in Cameroon.

PubMed

Sodjinou, Roger; Lezama, Ines; Asse, Marie-Louise; Okala, Georges; Bosu, William K; Fanou, Nadia; Mbala, Ludvine; Zagre, Noel Marie; Tchibindat, Félicité

2016-01-01

There is consensus among stakeholders in Cameroon on the need to develop and strengthen human resource capacity for nutrition. This study was conducted to provide a comprehensive mapping of the current capacity for tertiary-level human nutrition training in Cameroon. Participating institutions included university-level institutions offering dedicated nutrition degree programs or other programs in which nutrition courses were taught. A semi-structured questionnaire administered during in-person interviews was used to collect data on existing programs and content of training curricula. Nutrition curricula were reviewed against the following criteria: intended objectives, coverage of nutrition topics, and teaching methods. In total, five nutrition degree programs (four undergraduate programs and one master's program) were identified. Three additional programs were about to be launched at the time of data collection. We did not find any doctorate degree programs in nutrition. All the undergraduate programs only had little focus on public health nutrition whereas the master's program in our sample offered a good coverage of all dimensions of human nutrition including basic and applied nutrition. The predominant teaching method was didactic lecture in all the programs. We did not find any formal documentation outlining the competencies that students were expected to gain upon completion of these programs. Nutrition courses in agricultural and health schools were limited in terms of contact hours and scope. Public health nutrition was not covered in any of the health professional schools surveyed. We found no institution offering in-service nutrition training at the time of the study. Based on our findings, we recommend that nutrition training programs in Cameroon be redesigned to make them more responsive to the public health needs of the country.

A comprehensive mapping of the current capacity for human nutrition training in Cameroon

PubMed Central

Sodjinou, Roger; Lezama, Ines; Asse, Marie-Louise; Okala, Georges; Bosu, William K.; Fanou, Nadia; Mbala, Ludvine; Zagre, Noel Marie; Tchibindat, Félicité

2016-01-01

Background There is consensus among stakeholders in Cameroon on the need to develop and strengthen human resource capacity for nutrition. This study was conducted to provide a comprehensive mapping of the current capacity for tertiary-level human nutrition training in Cameroon. Design Participating institutions included university-level institutions offering dedicated nutrition degree programs or other programs in which nutrition courses were taught. A semi-structured questionnaire administered during in-person interviews was used to collect data on existing programs and content of training curricula. Nutrition curricula were reviewed against the following criteria: intended objectives, coverage of nutrition topics, and teaching methods. Results In total, five nutrition degree programs (four undergraduate programs and one master's program) were identified. Three additional programs were about to be launched at the time of data collection. We did not find any doctorate degree programs in nutrition. All the undergraduate programs only had little focus on public health nutrition whereas the master's program in our sample offered a good coverage of all dimensions of human nutrition including basic and applied nutrition. The predominant teaching method was didactic lecture in all the programs. We did not find any formal documentation outlining the competencies that students were expected to gain upon completion of these programs. Nutrition courses in agricultural and health schools were limited in terms of contact hours and scope. Public health nutrition was not covered in any of the health professional schools surveyed. We found no institution offering in-service nutrition training at the time of the study. Conclusions Based on our findings, we recommend that nutrition training programs in Cameroon be redesigned to make them more responsive to the public health needs of the country. PMID:26818193

Entropy-stable summation-by-parts discretization of the Euler equations on general curved elements

NASA Astrophysics Data System (ADS)

Crean, Jared; Hicken, Jason E.; Del Rey Fernández, David C.; Zingg, David W.; Carpenter, Mark H.

2018-03-01

We present and analyze an entropy-stable semi-discretization of the Euler equations based on high-order summation-by-parts (SBP) operators. In particular, we consider general multidimensional SBP elements, building on and generalizing previous work with tensor-product discretizations. In the absence of dissipation, we prove that the semi-discrete scheme conserves entropy; significantly, this proof of nonlinear L2 stability does not rely on integral exactness. Furthermore, interior penalties can be incorporated into the discretization to ensure that the total (mathematical) entropy decreases monotonically, producing an entropy-stable scheme. SBP discretizations with curved elements remain accurate, conservative, and entropy stable provided the mapping Jacobian satisfies the discrete metric invariants; polynomial mappings at most one degree higher than the SBP operators automatically satisfy the metric invariants in two dimensions. In three-dimensions, we describe an elementwise optimization that leads to suitable Jacobians in the case of polynomial mappings. The properties of the semi-discrete scheme are verified and investigated using numerical experiments.

Nonabelian noncommutative gauge theory via noncommutative extra dimensions

NASA Astrophysics Data System (ADS)

Jurčo, Branislav; Schupp, Peter; Wess, Julius

2001-06-01

The concept of covariant coordinates on noncommutative spaces leads directly to gauge theories with generalized noncommutative gauge fields of the type that arises in string theory with background B-fields. The theory is naturally expressed in terms of cochains in an appropriate cohomology; we discuss how it fits into the framework of projective modules. The equivalence of star products that arise from the background field with and without fluctuations and Kontsevich's formality theorem allow an explicitly construction of a map that relates ordinary gauge theory and noncommutative gauge theory (Seiberg-Witten map). As application we show the exact equality of the Dirac-Born-Infeld action with B-field in the commutative setting and its semi-noncommutative cousin in the intermediate picture. Using noncommutative extra dimensions the construction is extended to noncommutative nonabelian gauge theory for arbitrary gauge groups; an explicit map between abelian and nonabelian gauge fields is given. All constructions are also valid for non-constant B-field, Poisson structure and metric.

Landing Hazard Avoidance Display

NASA Technical Reports Server (NTRS)

Abernathy, Michael Franklin (Inventor); Hirsh, Robert L. (Inventor)

2016-01-01

Landing hazard avoidance displays can provide rapidly understood visual indications of where it is safe to land a vehicle and where it is unsafe to land a vehicle. Color coded maps can indicate zones in two dimensions relative to the vehicles position where it is safe to land. The map can be simply green (safe) and red (unsafe) areas with an indication of scale or can be a color coding of another map such as a surface map. The color coding can be determined in real time based on topological measurements and safety criteria to thereby adapt to dynamic, unknown, or partially known environments.

Exploring nonlinear feature space dimension reduction and data representation in breast CADx with Laplacian eigenmaps and t-SNE

PubMed Central

Jamieson, Andrew R.; Giger, Maryellen L.; Drukker, Karen; Li, Hui; Yuan, Yading; Bhooshan, Neha

2010-01-01

Purpose: In this preliminary study, recently developed unsupervised nonlinear dimension reduction (DR) and data representation techniques were applied to computer-extracted breast lesion feature spaces across three separate imaging modalities: Ultrasound (U.S.) with 1126 cases, dynamic contrast enhanced magnetic resonance imaging with 356 cases, and full-field digital mammography with 245 cases. Two methods for nonlinear DR were explored: Laplacian eigenmaps [M. Belkin and P. Niyogi, “Laplacian eigenmaps for dimensionality reduction and data representation,” Neural Comput. 15, 1373–1396 (2003)] and t-distributed stochastic neighbor embedding (t-SNE) [L. van der Maaten and G. Hinton, “Visualizing data using t-SNE,” J. Mach. Learn. Res. 9, 2579–2605 (2008)]. Methods: These methods attempt to map originally high dimensional feature spaces to more human interpretable lower dimensional spaces while preserving both local and global information. The properties of these methods as applied to breast computer-aided diagnosis (CADx) were evaluated in the context of malignancy classification performance as well as in the visual inspection of the sparseness within the two-dimensional and three-dimensional mappings. Classification performance was estimated by using the reduced dimension mapped feature output as input into both linear and nonlinear classifiers: Markov chain Monte Carlo based Bayesian artificial neural network (MCMC-BANN) and linear discriminant analysis. The new techniques were compared to previously developed breast CADx methodologies, including automatic relevance determination and linear stepwise (LSW) feature selection, as well as a linear DR method based on principal component analysis. Using ROC analysis and 0.632+bootstrap validation, 95% empirical confidence intervals were computed for the each classifier’s AUC performance. Results: In the large U.S. data set, sample high performance results include, AUC0.632+=0.88 with 95% empirical bootstrap interval [0.787;0.895] for 13 ARD selected features and AUC0.632+=0.87 with interval [0.817;0.906] for four LSW selected features compared to 4D t-SNE mapping (from the original 81D feature space) giving AUC0.632+=0.90 with interval [0.847;0.919], all using the MCMC-BANN. Conclusions: Preliminary results appear to indicate capability for the new methods to match or exceed classification performance of current advanced breast lesion CADx algorithms. While not appropriate as a complete replacement of feature selection in CADx problems, DR techniques offer a complementary approach, which can aid elucidation of additional properties associated with the data. Specifically, the new techniques were shown to possess the added benefit of delivering sparse lower dimensional representations for visual interpretation, revealing intricate data structure of the feature space. PMID:20175497

Human Dimensions of Forest Disturbance by Insects: An International Synthesis

Treesearch

Courtney G. Flint; Bonnie McFarlene; Martin Muller

2008-01-01

Ecological disturbances of forests by insects have a complex array of associated human dimensions presenting complications for natural resource decision making and relationships between stakeholders and managers. This article discusses the human context of forest disturbances by insects by reviewing four cases of bark beetle forest disturbance from British Columbia in...

Fractal dimensions of graph of Weierstrass-type function and local Hölder exponent spectra

NASA Astrophysics Data System (ADS)

Otani, Atsuya

2018-01-01

We study several fractal properties of the Weierstrass-type function where τ :[0, 1)\\to[0, 1) is a cookie cutter map with possibly fractal repeller, and λ and g are functions with proper regularity. In the first part, we determine the box dimension of the graph of W and Hausdorff dimension of its randomised version. In the second part, the Hausdorff spectrum of the local Hölder exponent is characterised in terms of thermodynamic formalism. Furthermore, in the randomised case, a novel formula for the lifted Hausdorff spectrum on the graph is provided.

Human Mind Maps

ERIC Educational Resources Information Center

Glass, Tom

2016-01-01

When students generate mind maps, or concept maps, the maps are usually on paper, computer screens, or a blackboard. Human Mind Maps require few resources and little preparation. The main requirements are space where students can move around and a little creativity and imagination. Mind maps can be used for a variety of purposes, and Human Mind…

Interleaved multishot imaging by spatiotemporal encoding: A fast, self-referenced method for high-definition diffusion and functional MRI.

PubMed

Schmidt, Rita; Seginer, Amir; Frydman, Lucio

2016-05-01

Single-shot imaging by spatiotemporal encoding (SPEN) can provide higher immunity to artifacts than its echo planar imaging-based counterparts. Further improvements in resolution and signal-to-noise ratio could be made by rescinding the sequence's single-scan nature. To explore this option, an interleaved SPEN version was developed that was capable of delivering optimized images due to its use of a referenceless correction algorithm. A characteristic element of SPEN encoding is the absence of aliasing when its signals are undersampled along the low-bandwidth dimension. This feature was exploited in this study to segment a SPEN experiment into a number of interleaved shots whose inaccuracies were automatically compared and corrected as part of a navigator-free image reconstruction analysis. This could account for normal phase noises, as well as for object motions during the signal collection. The ensuing interleaved SPEN method was applied to phantoms and human volunteers and delivered high-quality images even in inhomogeneous or mobile environments. Submillimeter functional MRI activation maps confined to gray matter regions as well as submillimeter diffusion coefficient maps of human brains were obtained. We have developed an interleaved SPEN approach for the acquisition of high-definition images that promises a wider range of functional and diffusion MRI applications even in challenging environments. © 2015 Wiley Periodicals, Inc.

Self-Organizing Neural Network Map for the Purpose of Visualizing the Concept Images of Students on Angles

ERIC Educational Resources Information Center

Kaya, Deniz

2017-01-01

The purpose of the study is to perform a less-dimensional thorough visualization process for the purpose of determining the images of the students on the concept of angle. The Ward clustering analysis combined with Self-Organizing Neural Network Map (SOM) has been used for the dimension process. The Conceptual Understanding Tool, which consisted…

Nautical Charts: Another Dimension in Developing Map Skills. Instructional Activities Series IA/S-11.

ERIC Educational Resources Information Center

McCallum, W. F.; Botly, D. H.

These activities are part of a series of 17 teacher-developed instructional activities for geography at the secondary-grade level described in SO 009 140. In the activities students develop map skills by learning about and using nautical charts. The first activity involves students in using parallel rulers and a compass rose to find their…

18 CFR 401.39 - Form of submission of projects not requiring prior approval by State or Federal agencies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... applicable; (2) General map showing specific location and dimension of a structural project, or specific...-structural project; (5) Written report of the applicant's engineer showing the proposed plan of operation of a structural project; (6) Map of any lands to be acquired or occupied; (7) Estimate of the cost of...

Intercreativity: Mapping Online Activism

NASA Astrophysics Data System (ADS)

Meikle, Graham

How do activists use the Internet? This article maps a wide range of activist practice and research by applying and developing Tim Berners-Lee's concept of ‘intercreativity' (1999). It identifies four dimensions of Net activism: intercreative texts, tactics, strategies and networks. It develops these through examples of manifestations of Net activism around one cluster of issues: support campaigns for refugees and asylum seekers.

Improving exposure assessment in environmental epidemiology: Application of spatio-temporal visualization tools

NASA Astrophysics Data System (ADS)

Meliker, Jaymie R.; Slotnick, Melissa J.; Avruskin, Gillian A.; Kaufmann, Andrew; Jacquez, Geoffrey M.; Nriagu, Jerome O.

2005-05-01

A thorough assessment of human exposure to environmental agents should incorporate mobility patterns and temporal changes in human behaviors and concentrations of contaminants; yet the temporal dimension is often under-emphasized in exposure assessment endeavors, due in part to insufficient tools for visualizing and examining temporal datasets. Spatio-temporal visualization tools are valuable for integrating a temporal component, thus allowing for examination of continuous exposure histories in environmental epidemiologic investigations. An application of these tools to a bladder cancer case-control study in Michigan illustrates continuous exposure life-lines and maps that display smooth, continuous changes over time. Preliminary results suggest increased risk of bladder cancer from combined exposure to arsenic in drinking water (>25 μg/day) and heavy smoking (>30 cigarettes/day) in the 1970s and 1980s, and a possible cancer cluster around automotive, paint, and organic chemical industries in the early 1970s. These tools have broad application for examining spatially- and temporally-specific relationships between exposures to environmental risk factors and disease.

Towards adaptive management of the natural capital: Disentangling trade-offs among marine activities and seagrass meadows.

PubMed

Bas Ventín, Leticia; de Souza Troncoso, Jesús; Villasante, Sebastián

2015-12-15

This paper investigates the ecological, social and institutional dimensions of the synergies and trade-offs between seagrasses and human activities operating in the Natura 2000 protected site of San Simón Bay (Galicia, NW Spain). By means of a multidisciplinary approach that brings together the development of a biological inventory combined with participatory mapping processes we get key spatial and contextual understanding regarding how, where and why marine users interact with seagrasses and how seagrasses are considered in policy making. The results highlight the fisheries' reliance on seagrass meadows and the controversial links with shellfisheries. The study also reveals unresolved conflicts among those management plans that promote the protection of natural values and those responsible for the exploitation of marine resources. We conclude that the adoption of pre-planning bottom-up participatory processes is crucial for the design of realistic strategies where both seagrasses and human activities were considered as a couple system. Copyright © 2015 Elsevier Ltd. All rights reserved.

The staircase method: integrals for periodic reductions of integrable lattice equations

NASA Astrophysics Data System (ADS)

van der Kamp, Peter H.; Quispel, G. R. W.

2010-11-01

We show, in full generality, that the staircase method (Papageorgiou et al 1990 Phys. Lett. A 147 106-14, Quispel et al 1991 Physica A 173 243-66) provides integrals for mappings, and correspondences, obtained as traveling wave reductions of (systems of) integrable partial difference equations. We apply the staircase method to a variety of equations, including the Korteweg-De Vries equation, the five-point Bruschi-Calogero-Droghei equation, the quotient-difference (QD)-algorithm and the Boussinesq system. We show that, in all these cases, if the staircase method provides r integrals for an n-dimensional mapping, with 2r, then one can introduce q <= 2r variables, which reduce the dimension of the mapping from n to q. These dimension-reducing variables are obtained as joint invariants of k-symmetries of the mappings. Our results support the idea that often the staircase method provides sufficiently many integrals for the periodic reductions of integrable lattice equations to be completely integrable. We also study reductions on other quad-graphs than the regular {\\ Z}^2 lattice, and we prove linear growth of the multi-valuedness of iterates of high-dimensional correspondences obtained as reductions of the QD-algorithm.

Simultaneous imaging of neural activity in three dimensions

PubMed Central

Quirin, Sean; Jackson, Jesse; Peterka, Darcy S.; Yuste, Rafael

2014-01-01

We introduce a scanless optical method to image neuronal activity in three dimensions simultaneously. Using a spatial light modulator and a custom-designed phase mask, we illuminate and collect light simultaneously from different focal planes and perform calcium imaging of neuronal activity in vitro and in vivo. This method, combining structured illumination with volume projection imaging, could be used as a technological platform for brain activity mapping. PMID:24772066

Mapping the Association of College and Research Libraries information literacy framework and nursing professional standards onto an assessment rubric.

PubMed

Willson, Gloria; Angell, Katelyn

2017-04-01

The authors developed a rubric for assessing undergraduate nursing research papers for information literacy skills critical to their development as researchers and health professionals. We developed a rubric mapping six American Nurses Association professional standards onto six related concepts of the Association of College & Research Libraries (ACRL) Framework for Information Literacy for Higher Education. We used this rubric to evaluate fifty student research papers and assess inter-rater reliability. Students tended to score highest on the "Information Has Value" dimension and lowest on the "Scholarship as Conversation" dimension. However, we found a discrepancy between the grading patterns of the two investigators, with inter-rater reliability being "fair" or "poor" for all six rubric dimensions. The development of a rubric that dually assesses information literacy skills and maps relevant disciplinary competencies holds potential. This study offers a template for a rubric inspired by the ACRL Framework and outside professional standards. However, the overall low inter-rater reliability demands further calibration of the rubric. Following additional norming, this rubric can be used to help students identify the key information literacy competencies that they need in order to succeed as college students and future nurses. These skills include developing an authoritative voice, determining the scope of their information needs, and understanding the ramifications of their information choices.

Mapping the Association of College and Research Libraries information literacy framework and nursing professional standards onto an assessment rubric

PubMed Central

Willson, Gloria; Angell, Katelyn

2017-01-01

Objective The authors developed a rubric for assessing undergraduate nursing research papers for information literacy skills critical to their development as researchers and health professionals. Methods We developed a rubric mapping six American Nurses Association professional standards onto six related concepts of the Association of College & Research Libraries (ACRL) Framework for Information Literacy for Higher Education. We used this rubric to evaluate fifty student research papers and assess inter-rater reliability. Results Students tended to score highest on the “Information Has Value” dimension and lowest on the “Scholarship as Conversation” dimension. However, we found a discrepancy between the grading patterns of the two investigators, with inter-rater reliability being “fair” or “poor” for all six rubric dimensions. Conclusions The development of a rubric that dually assesses information literacy skills and maps relevant disciplinary competencies holds potential. This study offers a template for a rubric inspired by the ACRL Framework and outside professional standards. However, the overall low inter-rater reliability demands further calibration of the rubric. Following additional norming, this rubric can be used to help students identify the key information literacy competencies that they need in order to succeed as college students and future nurses. These skills include developing an authoritative voice, determining the scope of their information needs, and understanding the ramifications of their information choices. PMID:28377678

Heisenberg symmetry and collective modes of one dimensional unitary correlated fermions

NASA Astrophysics Data System (ADS)

Abhinav, Kumar; Chandrasekhar, B.; Vyas, Vivek M.; Panigrahi, Prasanta K.

2017-02-01

The correlated fermionic many-particle system, near infinite scattering length, reveals an underlying Heisenberg symmetry in one dimension, as compared to an SO (2 , 1) symmetry in two dimensions. This facilitates an exact map from the interacting to the non-interacting system, both with and without a harmonic trap, and explains the short-distance scaling behavior of the wave-function. Taking advantage of the phenomenological Calogero-Sutherland-type interaction, motivated by the density functional approach, we connect the ground-state energy shift, to many-body correlation effect. For the excited states, modes at integral values of the harmonic frequency ω are predicted in one dimension, in contrast to the breathing modes with frequency 2ω in two dimensions.

The ARSQ 2.0 reveals age and personality effects on mind-wandering experiences

PubMed Central

Diaz, B. Alexander; Van Der Sluis, Sophie; Benjamins, Jeroen S.; Stoffers, Diederick; Hardstone, Richard; Mansvelder, Huibert D.; Van Someren, Eus J. W.; Linkenkaer-Hansen, Klaus

2014-01-01

The human brain frequently generates thoughts and feelings detached from environmental demands. Investigating the rich repertoire of these mind-wandering experiences is challenging, as it depends on introspection and mapping its content requires an unknown number of dimensions. We recently developed a retrospective self-report questionnaire—the Amsterdam Resting-State Questionnaire (ARSQ)—which quantifies mind wandering along seven dimensions: “Discontinuity of Mind,” “Theory of Mind,” “Self,” “Planning,” “Sleepiness,” “Comfort,” and “Somatic Awareness.” Here, we show using confirmatory factor analysis that the ARSQ can be simplified by standardizing the number of items per factor and extending it to a 10-dimensional model, adding “Health Concern,” “Visual Thought,” and “Verbal Thought.” We will refer to this extended ARSQ as the “ARSQ 2.0.” Testing for effects of age and gender revealed no main effect for gender, yet a moderate and significant negative effect for age on the dimensions of “Self,” “Planning,” and “Visual Thought.” Interestingly, we observed stable and significant test-retest correlations across measurement intervals of 3–32 months except for “Sleepiness” and “Health Concern.” To investigate whether this stability could be related to personality traits, we correlated ARSQ scores to proxy measures of Cloninger's Temperament and Character Inventory, revealing multiple significant associations for the trait “Self-Directedness.” Other traits correlated to specific ARSQ dimensions, e.g., a negative association between “Harm Avoidance” and “Comfort.” Together, our results suggest that the ARSQ 2.0 is a promising instrument for quantitative studies on mind wandering and its relation to other psychological or physiological phenomena. PMID:24772097

Comprehensive lipidomic analysis of human plasma using multidimensional liquid- and gas-phase separations: Two-dimensional liquid chromatography-mass spectrometry vs. liquid chromatography-trapped-ion-mobility-mass spectrometry.

PubMed

Baglai, Anna; Gargano, Andrea F G; Jordens, Jan; Mengerink, Ynze; Honing, Maarten; van der Wal, Sjoerd; Schoenmakers, Peter J

2017-12-29

Recent advancements in separation science have resulted in the commercialization of multidimensional separation systems that provide higher peak capacities and, hence, enable a more-detailed characterization of complex mixtures. In particular, two powerful analytical tools are increasingly used by analytical scientists, namely online comprehensive two-dimensional liquid chromatography (LC×LC, having a second-dimension separation in the liquid phase) and liquid chromatography-ion mobility-spectrometry (LC-IMS, second dimension separation in the gas phase). The goal of the current study was a general assessment of the liquid-chromatography-trapped-ion-mobility-mass spectrometry (LC-TIMS-MS) and comprehensive two-dimensional liquid chromatography-mass spectrometry (LC×LC-MS) platforms for untargeted lipid mapping in human plasma. For the first time trapped-ion-mobility spectrometry (TIMS) was employed for the separation of the major lipid classes and ion-mobility-derived collision-cross-section values were determined for a number of lipid standards. The general effects of a number of influencing parameters have been inspected and possible directions for improvements are discussed. We aimed to provide a general indication and practical guidelines for the analyst to choose an efficient multidimensional separation platform according to the particular requirements of the application. Analysis time, orthogonality, peak capacity, and an indicative measure for the resolving power are discussed as main characteristics for multidimensional separation systems. Copyright © 2017 Elsevier B.V. All rights reserved.

Exploring a fourth dimension: spirituality as a resource for the couple therapist.

PubMed

Anderson, D A; Worthen, D

1997-01-01

This article explores ways in which the therapist's own spirituality can serve as a resource in couple therapy. Spirituality is defined as subjective engagement with a fourth, transcendent dimension of human experience. This engagement enhances human life and evokes corresponding behavior. Spiritually based therapy may be influenced by three assumptions: that God or a Divine Being exists, that human-kind yearns innately for connection with this Being, and that this Being is interested in humans and acts upon and within their relationships to promote beneficial change. In therapy these assumptions affect how the therapist listens and responds throughout sessions. The authors incorporate a case example illustrating the application of this fourth dimension in couple therapy.

Effect of genetic background on the contribution of New Zealand Black loci to autoimmune lupus nephritis

PubMed Central

Rozzo, Stephen J.; Vyse, Timothy J.; Drake, Charles G.; Kotzin, Brian L.

1996-01-01

Autoimmune diseases such as systemic lupus erythematosus are complex genetic traits with contributions from major histocompatibility complex (MHC) genes and multiple unknown non-MHC genes. Studies of animal models of lupus have provided important insight into the immunopathogenesis of disease, and genetic analyses of these models overcome certain obstacles encountered when studying human patients. Genome-wide scans of different genetic crosses have been used to map several disease-linked loci in New Zealand hybrid mice. Although some consensus exists among studies mapping the New Zealand Black (NZB) and New Zealand White (NZW) loci that contribute to lupus-like disease, considerable variability is also apparent. A variable in these studies is the genetic background of the non-autoimmune strain, which could influence genetic contributions from the affected strain. A direct examination of this question was undertaken in the present study by mapping NZB nephritis-linked loci in backcrosses involving different non-autoimmune backgrounds. In a backcross with MHC-congenic C57BL/6J mice, H2z appeared to be the strongest genetic determinant of severe lupus nephritis, whereas in a backcross with congenic BALB/cJ mice, H2z showed no influence on disease expression. NZB loci on chromosomes 1, 4, 11, and 14 appeared to segregate with disease in the BALB/cJ cross, but only the influence of the chromosome 1 locus spanned both crosses and showed linkage with disease when all mice were considered. Thus, the results indicate that contributions from disease-susceptibility loci, including MHC, may vary markedly depending on the non-autoimmune strain used in a backcross analysis. These studies provide insight into variables that affect genetic heterogeneity and add an important dimension of complexity for linkage analyses of human autoimmune disease. PMID:8986781

Managing black walnut in natural stands: the human dimension

Treesearch

H.E. " Hank" Stelzer

2004-01-01

In managing black walnut, or any forest tree species, the human dimension is often overlooked. As a result, both the number of landowners managing their land and the number of forested acres under management has not significantly increased over the past 30 years. Elements of the human landscape are explored and a roadmap for engaging landowners is proposed.

Dimensions of Human-Work Domain Interaction: A Preliminary Analysis for the Design of a Corporate Digital Library.

ERIC Educational Resources Information Center

Xie, Hong

2003-01-01

Applies the cognitive system engineering approach to investigate human-work interaction at a corporate setting. Reports preliminary analysis of data collected from diary analysis and interview of 20 subjects. Results identify three dimensions for each of four interactive activities involved in human-work interaction and their relationships.…

Content analysis to detect high stress in oral interviews and text documents

NASA Technical Reports Server (NTRS)

Thirumalainambi, Rajkumar (Inventor); Jorgensen, Charles C. (Inventor)

2012-01-01

A system of interrogation to estimate whether a subject of interrogation is likely experiencing high stress, emotional volatility and/or internal conflict in the subject's responses to an interviewer's questions. The system applies one or more of four procedures, a first statistical analysis, a second statistical analysis, a third analysis and a heat map analysis, to identify one or more documents containing the subject's responses for which further examination is recommended. Words in the documents are characterized in terms of dimensions representing different classes of emotions and states of mind, in which the subject's responses that manifest high stress, emotional volatility and/or internal conflict are identified. A heat map visually displays the dimensions manifested by the subject's responses in different colors, textures, geometric shapes or other visually distinguishable indicia.

Generating multiple independent retention index data in dual-secondary column comprehensive two-dimensional gas chromatography.

PubMed

Bieri, Stefan; Marriott, Philip J

2006-12-01

A method producing simultaneously three retention indexes for compounds has been developed for comprehensive two-dimensional gas chromatography by using a dual secondary column approach (GC x 2GC). For this purpose, the primary flow of the first dimension column was equally diverted into two secondary microbore columns of identical geometry by means of a three-way flow splitter positioned after the longitudinally modulated cryogenic system. This configuration produced a pair of comprehensive two-dimensional chromatograms and generated retention data on three different stationary phases in a single run. First dimension retention indexes were determined on a polar SolGel-Wax column under linear programmed-temperature conditions according to the van den Dool approach using primary alcohol homologues as the reference scale. Calculation of pseudoisothermal retention indexes in both second dimensions was performed on low-polarity 5% phenyl equivalent polysilphenylene/siloxane (BPX5) and 14% cyanopropylphenyl/86% dimethylpolysiloxane (BP10) columns. To construct a retention correlation map in the second dimension separation space upon which KovAts indexes can be derived, two methods exploiting "isovolatility" relationships of alkanes were developed. The first involved 15 sequential headspace samplings of selected n-alkanes by solid-phase microextraction (SPME), with each sampling followed by their injection into the GC at predetermined times during the chromatographic run. The second method extended the second dimension retention map and consisted of repetitive introduction of SPME-sampled alkane mixtures at various isothermal conditions incremented over the temperature program range. Calculated second dimension retention indexes were compared with experimental values obtained in conventional one-dimensional GC. A case study mixture including 24 suspected allergens (i.e., fragrance ingredients) was used to demonstrate the feasibility and potential of retention index information in comprehensive 2D-GC.

Influence of consumers' cognitive style on results from projective mapping.

PubMed

Varela, Paula; Antúnez, Lucía; Berget, Ingunn; Oliveira, Denize; Christensen, Kasper; Vidal, Leticia; Naes, Tormod; Ares, Gastón

2017-09-01

Projective mapping (PM), one of the most holistic product profiling methods in approach, is increasingly being used to uncover consumers' perception of products and packages. Assessors rely on a process of synthesis for evaluating product information, which would determine the relative importance of the perceived characteristics they use for mapping them. Individual differences are expected, as participants are not instructed on the characteristics to consider for evaluating the degree of difference among samples, generating different perceptual spaces. Individual differences in cognitive style can affect synthesis processes and thus their perception of similarities and differences among samples. In this study, the influence of the cognitive style in the results of PM was explored. Two consumer studies were performed, one aimed at describing intrinsic sensory characteristics of chocolate flavoured milk and the other one looking into extrinsic (package only) of blueberry yogurts. Consumers completed the wholistic-analytic module of the extended Verbal Imagery Cognitive Styles Test & Extended Cognitive Style Analysis-Wholistic Analytic Test, to characterize their cognitive style. Differences between wholistic and analytic consumers in how they evaluated samples using projective mapping were found in both studies. Analytics separated the samples more in the PM perceptual space than wholistic consumers, showing more discriminating abilities. This may come from a deeper analysis of the samples, both from intrinsic and extrinsic point of views. From a sensory perspective (intrinsic), analytic consumers relied on more sensory characteristics, while wholistic mainly discriminated samples according to sweetness and bitterness/chocolate flavour. In the extrinsic study however, even if analytic consumers discriminated more between packs, they described the products using similar words in the descriptive step. One important recommendation coming from this study is the need to consider higher dimensions in the interpretation of projective mapping tasks, as the first dimensions could underestimate the complexity of the perceptual space; currently, most applications of PM consider two dimensions only, which may not uncover the perception of specific groups of consumers. Copyright © 2017 Elsevier Ltd. All rights reserved.

Current status of Mycobacterium avium subspecies paratuberculosis infection in animals & humans in India: What needs to be done?

PubMed

Singh, Ajay Vir; Chauhan, Devendra Singh; Singh, Shoor Vir; Kumar, Vijay; Singh, Abhinendra; Yadav, Anjali; Yadav, Virendra Singh

2016-11-01

Mycobacterium avium subspecies paratuberculosis (MAP) has emerged as a major health problem for domestic livestock and human beings. Reduced per animal productivity of domestic livestock seriously impacts the economics of dairy farming globally. High to very high bioload of MAP in domestic livestock and also in the human population has been reported from north India. Presence of live MAP bacilli in commercial supplies of raw and pasteurized milk and milk products indicates its public health significance. MAP is not inactivated during pasteurization, therefore, entering into human food chain daily. Recovery of MAP from patients with inflammatory bowel disease or Crohn's disease and animal healthcare workers suffering with chronic gastrointestinal problems indicate a close association of MAP with a number of chronic and other diseases affecting human health. Higher bioload of MAP in the animals increases the risk of exposure to the human population with MAP. This review summarizes the current status of MAP infection in animals as well as in human beings and also highlights the prospects of effective management and control of disease in animals to reduce the risk of exposure to human population.

3D Myocardial Elastography In Vivo.

PubMed

Papadacci, Clement; Bunting, Ethan A; Wan, Elaine Y; Nauleau, Pierre; Konofagou, Elisa E

2017-02-01

Strain evaluation is of major interest in clinical cardiology as it can quantify the cardiac function. Myocardial elastography, a radio-frequency (RF)-based cross-correlation method, has been developed to evaluate the local strain distribution in the heart in vivo. However, inhomogeneities such as RF ablation lesions or infarction require a three-dimensional approach to be measured accurately. In addition, acquisitions at high volume rate are essential to evaluate the cardiac strain in three dimensions. Conventional focused transmit schemes using 2D matrix arrays, trade off sufficient volume rate for beam density or sector size to image rapid moving structure such as the heart, which lowers accuracy and precision in the strain estimation. In this study, we developed 3D myocardial elastography at high volume rates using diverging wave transmits to evaluate the local axial strain distribution in three dimensions in three open-chest canines before and after radio-frequency ablation. Acquisitions were performed with a 2.5 MHz 2D matrix array fully programmable used to emit 2000 diverging waves at 2000 volumes/s. Incremental displacements and strains enabled the visualization of rapid events during the QRS complex along with the different phases of the cardiac cycle in entire volumes. Cumulative displacement and strain volumes depict high contrast between non-ablated and ablated myocardium at the lesion location, mapping the tissue coagulation. 3D myocardial strain elastography could thus become an important technique to measure the regional strain distribution in three dimensions in humans.

Modeling Semantic Emotion Space Using a 3D Hypercube-Projection: An Innovative Analytical Approach for the Psychology of Emotions

PubMed Central

Trnka, Radek; Lačev, Alek; Balcar, Karel; Kuška, Martin; Tavel, Peter

2016-01-01

The widely accepted two-dimensional circumplex model of emotions posits that most instances of human emotional experience can be understood within the two general dimensions of valence and activation. Currently, this model is facing some criticism, because complex emotions in particular are hard to define within only these two general dimensions. The present theory-driven study introduces an innovative analytical approach working in a way other than the conventional, two-dimensional paradigm. The main goal was to map and project semantic emotion space in terms of mutual positions of various emotion prototypical categories. Participants (N = 187; 54.5% females) judged 16 discrete emotions in terms of valence, intensity, controllability and utility. The results revealed that these four dimensional input measures were uncorrelated. This implies that valence, intensity, controllability and utility represented clearly different qualities of discrete emotions in the judgments of the participants. Based on this data, we constructed a 3D hypercube-projection and compared it with various two-dimensional projections. This contrasting enabled us to detect several sources of bias when working with the traditional, two-dimensional analytical approach. Contrasting two-dimensional and three-dimensional projections revealed that the 2D models provided biased insights about how emotions are conceptually related to one another along multiple dimensions. The results of the present study point out the reductionist nature of the two-dimensional paradigm in the psychological theory of emotions and challenge the widely accepted circumplex model. PMID:27148130

Surrogate Structures for Computationally Expensive Optimization Problems With CPU-Time Correlated Functions

DTIC Science & Technology

2007-06-01

xc)−∇2g(x̃c)](x− xc). The second transformation is a space mapping function P that handles the change in variable dimensions (see Bandler et al. [11...17(2):188–217, 2004. 11. Bandler, J. W., Q. Cheng, S. Dakroury, A. S. Mohamed, M.H. Bakr, K. Madsen, J. Søndergaard. “ Space Mapping : The State of

A Mapping from the Human Factors Analysis and Classification System (DOD-HFACS) to the Domains of Human Systems Integration (HSI)

DTIC Science & Technology

2009-11-01

Equation Chapter 1 Section 1 A MAPPING FROM THE HUMAN FACTORS ANALYSIS AND CLASSIFICATION SYSTEM (DOD...OMB control number. 1. REPORT DATE NOV 2009 2. REPORT TYPE 3. DATES COVERED 4. TITLE AND SUBTITLE A Mapping from the Human Factors Analysis ...7 The Human Factors Analysis and Classification System .................................................. 7 Mapping of DoD

Homological Order in Three and Four dimensions: Wilson Algebra, Entanglement Entropy and Twist Defects

NASA Astrophysics Data System (ADS)

Roy, Abhishek; Chen, Xiao; Teo, Jeffrey

2013-03-01

We investigate homological orders in two, three and four dimensions by studying Zk toric code models on simplicial, cellular or in general differential complexes. The ground state degeneracy is obtained from Wilson loop and surface operators, and the homological intersection form. We compute these for a series of closed 3 and 4 dimensional manifolds and study the projective representations of mapping class groups (modular transformations). Braiding statistics between point and string excitations in (3+1)-dimensions or between dual string excitations in (4+1)-dimensions are topologically determined by the higher dimensional linking number, and can be understood by an effective topological field theory. An algorithm for calculating entanglemnent entropy of any bipartition of closed manifolds is presented, and its topological signature is completely characterized homologically. Extrinsic twist defects (or disclinations) are studied in 2,3 and 4 dimensions and are shown to carry exotic fusion and braiding properties. Simons Fellowship

Exploring relationships of human-automation interaction consequences on pilots: uncovering subsystems.

PubMed

Durso, Francis T; Stearman, Eric J; Morrow, Daniel G; Mosier, Kathleen L; Fischer, Ute; Pop, Vlad L; Feigh, Karen M

2015-05-01

We attempted to understand the latent structure underlying the systems pilots use to operate in situations involving human-automation interaction (HAI). HAI is an important characteristic of many modern work situations. Of course, the cognitive subsystems are not immediately apparent by observing a functioning system, but correlations between variables may reveal important relations. The current report examined pilot judgments of 11 HAI dimensions (e.g., Workload, Task Management, Stress/Nervousness, Monitoring Automation, and Cross-Checking Automation) across 48 scenarios that required airline pilots to interact with automation on the flight deck. We found three major clusters of the dimensions identifying subsystems on the flight deck: a workload subsystem, a management subsystem, and an awareness subsystem. Relationships characterized by simple correlations cohered in ways that suggested underlying subsystems consistent with those that had previously been theorized. Understanding the relationship among dimensions affecting HAI is an important aspect in determining how a new piece of automation designed to affect one dimension will affect other dimensions as well. © 2014, Human Factors and Ergonomics Society.

US Topo Product Standard

USGS Publications Warehouse

Cooley, Michael J.; Davis, Larry R.; Fishburn, Kristin A.; Lestinsky, Helmut; Moore, Laurence R.

2011-01-01

A full-size style sheet template in PDF that defines the placement of map elements, marginalia, and font sizes and styles accompanies this standard. The GeoPDF US Topo maps are fashioned to conform to this style sheet so that a user can print out a map at the 1:24,000-scale using the dimensions of the traditional standard 7.5-minute quadrangle. Symbology and type specifications for feature content are published separately. In addition, the GeoPDF design allows for custom printing, so that a user may zoom in and out, turn layers on and off, and view or print any combination of layers or any map portion at any desired scale.

FAST TRACK COMMUNICATION: Weyl law for fat fractals

NASA Astrophysics Data System (ADS)

Spina, María E.; García-Mata, Ignacio; Saraceno, Marcos

2010-10-01

It has been conjectured that for a class of piecewise linear maps the closure of the set of images of the discontinuity has the structure of a fat fractal, that is, a fractal with positive measure. An example of such maps is the sawtooth map in the elliptic regime. In this work we analyze this problem quantum mechanically in the semiclassical regime. We find that the fraction of states localized on the unstable set satisfies a modified fractal Weyl law, where the exponent is given by the exterior dimension of the fat fractal.

Noncommutative gauge theories and Kontsevich's formality theorem

NASA Astrophysics Data System (ADS)

Jurčo, B.; Schupp, P.; Wess, J.

2001-09-01

The equivalence of star products that arise from the background field with and without fluctuations and Kontsevich's formality theorem allow an explicitly construction of a map that relates ordinary gauge theory and noncommutative gauge theory (Seiberg-Witten map.) Using noncommutative extra dimensions the construction is extended to noncommutative nonabelian gauge theory for arbitrary gauge groups; as a byproduct we obtain a "Mini Seiberg-Witten map" that explicitly relates ordinary abelian and nonabelian gauge fields. All constructions are also valid for non-constant B-field, and even more generally for any Poisson tensor.

Beyond 3-D: The New Spectrum of Lidar Applications for Earth and Ecological Sciences

NASA Technical Reports Server (NTRS)

Eitel, Jan U. H.; Hofle, Bernhard; Vierling, Lee A.; Abellan, Antonio; Asner, Gregory P.; Deems, Jeffrey S.; Glennie, Craig L.; Joerg, Phillip C.; LeWinter, Adam L.; Magney, Troy S.;

Fractal dimension of the middle meningeal vessels: variation and evolution in Homo erectus, Neanderthals, and modern humans.

PubMed

Bruner, Emiliano; Mantini, Simone; Perna, Agostino; Maffei, Carlotta; Manzi, Giorgio

2005-01-01

The middle meningeal vascular network leaves its traces on the endocranial surface because of the tight relationship between neurocranial development and brain growth. Analysing the endocast of fossil specimens, it is therefore possible to describe the morphology of these structures, leading inferences on the cerebral physiology and metabolism in extinct human groups. In this paper, general features of the meningeal vascular traces are described for specimens included in the Homo erectus, Homo neanderthalensis, and Homo sapiens hypodigms. The complexity of the arterial network is quantified by its fractal dimension, calculated through the box-counting method. Modern humans show significant differences from the other two taxa because of the anterior vascular dominance and the larger fractal dimension. Neither the fractal dimension nor the anterior development are merely associated with cranial size increase. Considering the differences between Neanderthals and modern humans, these results may be interpreted in terms of phylogeny, cerebral functions, or cranial structural network.

Velocity statistics for interacting edge dislocations in one dimension from Dyson's Coulomb gas model.

PubMed

Jafarpour, Farshid; Angheluta, Luiza; Goldenfeld, Nigel

2013-10-01

The dynamics of edge dislocations with parallel Burgers vectors, moving in the same slip plane, is mapped onto Dyson's model of a two-dimensional Coulomb gas confined in one dimension. We show that the tail distribution of the velocity of dislocations is power law in form, as a consequence of the pair interaction of nearest neighbors in one dimension. In two dimensions, we show the presence of a pairing phase transition in a system of interacting dislocations with parallel Burgers vectors. The scaling exponent of the velocity distribution at effective temperatures well below this pairing transition temperature can be derived from the nearest-neighbor interaction, while near the transition temperature, the distribution deviates from the form predicted by the nearest-neighbor interaction, suggesting the presence of collective effects.

Analysis of the fractal dimension of volcano geomorphology through Synthetic Aperture Radar (SAR) amplitude images acquired in C and X band.

NASA Astrophysics Data System (ADS)

Pepe, S.; Di Martino, G.; Iodice, A.; Manzo, M.; Pepe, A.; Riccio, D.; Ruello, G.; Sansosti, E.; Tizzani, P.; Zinno, I.

2012-04-01

In the last two decades several aspects relevant to volcanic activity have been analyzed in terms of fractal parameters that effectively describe natural objects geometry. More specifically, these researches have been aimed at the identification of (1) the power laws that governed the magma fragmentation processes, (2) the energy of explosive eruptions, and (3) the distribution of the associated earthquakes. In this paper, the study of volcano morphology via satellite images is dealt with; in particular, we use the complete forward model developed by some of the authors (Di Martino et al., 2012) that links the stochastic characterization of amplitude Synthetic Aperture Radar (SAR) images to the fractal dimension of the imaged surfaces, modelled via fractional Brownian motion (fBm) processes. Based on the inversion of such a model, a SAR image post-processing has been implemented (Di Martino et al., 2010), that allows retrieving the fractal dimension of the observed surfaces, dictating the distribution of the roughness over different spatial scales. The fractal dimension of volcanic structures has been related to the specific nature of materials and to the effects of active geodynamic processes. Hence, the possibility to estimate the fractal dimension from a single amplitude-only SAR image is of fundamental importance for the characterization of volcano structures and, moreover, can be very helpful for monitoring and crisis management activities in case of eruptions and other similar natural hazards. The implemented SAR image processing performs the extraction of the point-by-point fractal dimension of the scene observed by the sensor, providing - as an output product - the map of the fractal dimension of the area of interest. In this work, such an analysis is performed on Cosmo-SkyMed, ERS-1/2 and ENVISAT images relevant to active stratovolcanoes in different geodynamic contexts, such as Mt. Somma-Vesuvio, Mt. Etna, Vulcano and Stromboli in Southern Italy, Shinmoe in Japan, Merapi in Indonesia. Preliminary results reveal that the fractal dimension of natural areas, being related only to the roughness of the observed surface, is very stable as the radar illumination geometry, the resolution and the wavelength change, thus holding a very unique property in SAR data inversion. Such a behavior is not verified in case of non-natural objects. As a matter of fact, when the fractal estimation is performed in the presence of either man-made objects or SAR image features depending on geometrical distortions due to the SAR system acquisition (i.e. layover, shadowing), fractal dimension (D) values outside the range of fractality of natural surfaces (2 < D < 3) are retrieved. These non-fractal characteristics show to be heavily dependent on sensor acquisition parameters (e.g. view angle, resolution). In this work, the behaviour of the maps generated starting from the C- and X- band SAR data, relevant to all the considered volcanoes, is analyzed: the distribution of the obtained fractal dimension values is investigated on different zones of the maps. In particular, it is verified that the fore-slope and back-slope areas of the image share a very similar fractal dimension distribution that is placed around the mean value of D=2.3. We conclude that, in this context, the fractal dimension could be considered as a signature of the identification of the volcano growth as a natural process. The COSMO-SkyMed data used in this study have been processed at IREA-CNR within the SAR4Volcanoes project under Italian Space Agency agreement n. I/034/11/0.

Impact of emotional intelligence and spiritual intelligence on the caring behavior of nurses: a dimension-level exploratory study among public hospitals in Malaysia.

PubMed

Kaur, Devinder; Sambasivan, Murali; Kumar, Naresh

2015-11-01

The purpose of this research is to study the impact of individual factors such as emotional intelligence (EI) and spiritual intelligence (SI) on the caring behavior of nurses. A cross-sectional survey using questionnaire was conducted by sampling 550 nurses working in seven major public hospitals in Malaysia. Data were analyzed using structural equation modeling (SEM). The main findings are: (1) critical existential thinking and transcendental awareness dimensions of SI have significant impacts on assurance of human presence dimension of caring behavior; (2) personal meaning production and conscious state expansion dimensions of SI have significant impacts on perception of emotion and managing own emotions dimensions of EI; and (3) managing own emotions dimension of EI has significant impacts on respectful deference to other and assurance of human presence dimensions of caring behavior of nurses. The results can be used to recruit and educate nurses. Copyright © 2015 Elsevier Inc. All rights reserved.

Colloque S&T Symposium 2007: Understanding The Human Dimension in 21st Century Conflict/Warfare (Comprendre la Dimension Humaine du Conflit et de la Conduite de la Guerre au XXIe Siecle)

DTIC Science & Technology

2007-08-01

represented by the Minister of National Defence, 2007 © Sa Majesté la Reine (en droit du Canada), telle que représentée par le ministre de la Défense...grandes œuvres historiques de fiction : Guerre et paix de Tolstoï, Le vieil homme et la mer d’Hemingway, Hamlet de Shakespeare, et Les Misérables de ...Colloque S&T Symposium 2007 Understanding The Human Dimension in 21st Century Conflict/Warfare - Comprendre la dimension humaine du conflit et de

Nonuniform dependence on initial data for compressible gas dynamics: The periodic Cauchy problem

NASA Astrophysics Data System (ADS)

Keyfitz, B. L.; Tığlay, F.

2017-11-01

We start with the classic result that the Cauchy problem for ideal compressible gas dynamics is locally well posed in time in the sense of Hadamard; there is a unique solution that depends continuously on initial data in Sobolev space Hs for s > d / 2 + 1 where d is the space dimension. We prove that the data to solution map for periodic data in two dimensions although continuous is not uniformly continuous.

18 CFR 806.11 - Preliminary consultations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... proposed project, a map showing its location and, to the extent available, data concerning dimensions of... consultation is optional for the project sponsor (except with respect to aquifer test plans, see § 806.12 but...

On the Concept "Chemical Equilibrium": The Associative Framework.

ERIC Educational Resources Information Center

Gussarsky, Esther; Gorodetsky, Malka

1990-01-01

Word associations were used to map high school students' concepts of "chemical equilibrium" and "equilibrium." It was found that the preconception of the two concepts was differentiated on noncritical dimensions. (Author/CW)

Design Considerations for Computer-Based Interactive Map Display Systems

DTIC Science & Technology

1979-02-01

11 Five Dimensions for Map Display System Options . . . . . . . . . . . . . . . 12 Summary of...most advanced and exotic technologies- space , optical, computer, and graphic pro- duction; the focusing of vast organizational efforts; and the results...Information retrieval: "Where are all the radar sites in sector 12 ?," "What’s the name of this hill?," "Where’s the hill named B243?" Information storage

Digital image analysis: improving accuracy and reproducibility of radiographic measurement.

PubMed

Bould, M; Barnard, S; Learmonth, I D; Cunningham, J L; Hardy, J R

1999-07-01

To assess the accuracy and reproducibility of a digital image analyser and the human eye, in measuring radiographic dimensions. We experimentally compared radiographic measurement using either an image analyser system or the human eye with digital caliper. The assessment of total hip arthroplasty wear from radiographs relies on both the accuracy of radiographic images and the accuracy of radiographic measurement. Radiographs were taken of a slip gauge (30+/-0.00036 mm) and slip gauge with a femoral stem. The projected dimensions of the radiographic images were calculated by trigonometry. The radiographic dimensions were then measured by blinded observers using both techniques. For a single radiograph, the human eye was accurate to 0.26 mm and reproducible to +/-0.1 mm. In comparison the digital image analyser system was accurate to 0.01 mm with a reproducibility of +/-0.08 mm. In an arthroplasty model, where the dimensions of an object were corrected for magnification by the known dimensions of a femoral head, the human eye was accurate to 0.19 mm, whereas the image analyser system was accurate to 0.04 mm. The digital image analysis system is up to 20 times more accurate than the human eye, and in an arthroplasty model the accuracy of measurement increases four-fold. We believe such image analysis may allow more accurate and reproducible measurement of wear from standard follow-up radiographs.

Does Value Stream Mapping affect the structure, process, and outcome quality in care facilities? A systematic review.

PubMed

Nowak, Marina; Pfaff, Holger; Karbach, Ute

2017-08-24

Quality improvement within health and social care facilities is needed and has to be evidence-based and patient-centered. Value Stream Mapping, a method of Lean management, aims to increase the patients' value and quality of care by a visualization and quantification of the care process. The aim of this research is to examine the effectiveness of Value Stream Mapping on structure, process, and outcome quality in care facilities. A systematic review is conducted. PubMed, EBSCOhost, including Business Source Complete, Academic Search Complete, PSYCInfo, PSYNDX, SocINDEX with Full Text, Web of Knowledge, and EMBASE ScienceDirect are searched in February 2016. All peer-reviewed papers evaluating Value Stream Mapping and published in English or German from January 2000 are included. For data synthesis, all study results are categorized into Donabedian's model of structure, process, and outcome quality. To assess and interpret the effectiveness of Value Stream Mapping, the frequencies of the results statistically examined are considered. Of the 903 articles retrieved, 22 studies fulfill the inclusion criteria. Of these, 11 studies are used to answer the research question. Value Stream Mapping has positive effects on the time dimension of process and outcome quality. It seems to reduce non-value-added time (e.g., waiting time) and length of stay. All study designs are before and after studies without control, and methodologically sophisticated studies are missing. For a final conclusion about Value Stream Mapping's effectiveness, more research with improved methodology is needed. Despite this lack of evidence, Value Stream Mapping has the potential to improve quality of care on the time dimension. The contextual influence has to be investigated to make conclusions about the relationship between different quality domains when applying Value Stream Mapping. However, for using this review's conclusion, the limitation of including heterogeneous and potentially biased results has to be considered.

Counseling Gay Men with AIDS: Human Dimensions.

ERIC Educational Resources Information Center

Barret, Robert L.

1989-01-01

Provides case material that demonstrates the emotional response of homosexual men to Acquired Immune Deficiency Syndrome (AIDS). Discusses denial, anger, rage, guilt, and shame experienced by these men with an emphasis on the human dimensions of AIDS. Concludes that most powerful contribution of counselors is their willingness to "be with" persons…

Necessary Contributions of Human Frontal Lobe Subregions to Reward Learning in a Dynamic, Multidimensional Environment.

PubMed

Vaidya, Avinash R; Fellows, Lesley K

2016-09-21

Real-world decisions are typically made between options that vary along multiple dimensions, requiring prioritization of the important dimensions to support optimal choice. Learning in this setting depends on attributing decision outcomes to the dimensions with predictive relevance rather than to dimensions that are irrelevant and nonpredictive. This attribution problem is computationally challenging, and likely requires an interplay between selective attention and reward learning. Both these processes have been separately linked to the prefrontal cortex, but little is known about how they combine to support learning the reward value of multidimensional stimuli. Here, we examined the necessary contributions of frontal lobe subregions in attributing feedback to relevant and irrelevant dimensions on a trial-by-trial basis in humans. Patients with focal frontal lobe damage completed a demanding reward learning task where options varied on three dimensions, only one of which predicted reward. Participants with left lateral frontal lobe damage attributed rewards to irrelevant dimensions, rather than the relevant dimension. Damage to the ventromedial frontal lobe also impaired learning about the relevant dimension, but did not increase reward attribution to irrelevant dimensions. The results argue for distinct roles for these two regions in learning the value of multidimensional decision options under dynamic conditions, with the lateral frontal lobe required for selecting the relevant dimension to associate with reward, and the ventromedial frontal lobe required to learn the reward association itself. The real world is complex and multidimensional; how do we attribute rewards to predictive features when surrounded by competing cues? Here, we tested the critical involvement of human frontal lobe subregions in a probabilistic, multidimensional learning environment, asking whether focal lesions affected trial-by-trial attribution of feedback to relevant and irrelevant dimensions. The left lateral frontal lobe was required for filtering option dimensions to allow appropriate feedback attribution, while the ventromedial frontal lobe was necessary for learning the value of features in the relevant dimension. These findings argue that selective attention and associative learning processes mediated by anatomically distinct frontal lobe subregions are both critical for adaptive choice in more complex, ecologically valid settings. Copyright © 2016 the authors 0270-6474/16/369843-16$15.00/0.

Direct evidence from intraoperative electrocortical stimulation indicates shared and distinct speech production center between Chinese and English languages.

PubMed

Wu, Jinsong; Lu, Junfeng; Zhang, Han; Zhang, Jie; Yao, Chengjun; Zhuang, Dongxiao; Qiu, Tianming; Guo, Qihao; Hu, Xiaobing; Mao, Ying; Zhou, Liangfu

2015-12-01

Chinese processing has been suggested involving distinct brain areas from English. However, current functional localization studies on Chinese speech processing use mostly "indirect" techniques such as functional magnetic resonance imaging and electroencephalography, lacking direct evidence by means of electrocortical recording. In this study, awake craniotomies in 66 Chinese-speaking glioma patients provide a unique opportunity to directly map eloquent language areas. Intraoperative electrocortical stimulation was conducted and the positive sites for speech arrest, anomia, and alexia were identified separately. With help of stereotaxic neuronavigation system and computational modeling, all positive sites elicited by stimulation were integrated and a series of two- and three-dimension Chinese language probability maps were built. We performed statistical comparisons between the Chinese maps and previously derived English maps. While most Chinese speech arrest areas located at typical language production sites (i.e., 50% positive sites in ventral precentral gyrus, 28% in pars opercularis and pars triangularis), which also serve English production, an additional brain area, the left middle frontal gyrus (Brodmann's areas 6/9), was found to be unique in Chinese production (P < 0.05). Moreover, Chinese speakers' inferior ventral precentral gyrus (Brodmann's area 6) was used more than that in English speakers. Our finding suggests that Chinese involves more perisylvian region (extending to left middle frontal gyrus) than English. This is the first time that direct evidence supports cross-cultural neurolinguistics differences in human beings. The Chinese language atlas will also helpful in brain surgery planning for Chinese-speakers. Copyright © 2015 Wiley Periodicals, Inc.

Mapping opportunities and challenges for rewilding in Europe.

PubMed

Ceaușu, Silvia; Hofmann, Max; Navarro, Laetitia M; Carver, Steve; Verburg, Peter H; Pereira, Henrique M

2015-08-01

Farmland abandonment takes place across the world due to socio-economic and ecological drivers. In Europe agricultural and environmental policies aim to prevent abandonment and halt ecological succession. Ecological rewilding has been recently proposed as an alternative strategy. We developed a framework to assess opportunities for rewilding across different dimensions of wilderness in Europe. We mapped artificial light, human accessibility based on transport infrastructure, proportion of harvested primary productivity (i.e., ecosystem productivity appropriated by humans through agriculture or forestry), and deviation from potential natural vegetation in areas projected to be abandoned by 2040. At the continental level, the levels of artificial light were low and the deviation from potential natural vegetation was high in areas of abandonment. The relative importance of wilderness metrics differed regionally and was strongly connected to local environmental and socio-economic contexts. Large areas of projected abandonment were often located in or around Natura 2000 sites. Based on these results, we argue that management should be tailored to restore the aspects of wilderness that are lacking in each region. There are many remaining challenges regarding biodiversity in Europe, but megafauna species are already recovering. To further potentiate large-scale rewilding, Natura 2000 management would need to incorporate rewilding approaches. Our framework can be applied to assessing rewilding opportunities and challenges in other world regions, and our results could guide redirection of subsidies to manage social-ecological systems. © 2015 The Authors. Conservation Biology published by wiley Periodicals, Inc. on behalf of the Society for Conservation Biology.

Some constructions of biharmonic maps and Chen’s conjecture on biharmonic hypersurfaces

NASA Astrophysics Data System (ADS)

Ou, Ye-Lin

2012-04-01

We give several construction methods and use them to produce many examples of proper biharmonic maps including biharmonic tori of any dimension in Euclidean spheres (Theorem 2.2, Corollaries 2.3, 2.4 and 2.6), biharmonic maps between spheres (Theorem 2.9) and into spheres (Theorem 2.10) via orthogonal multiplications and eigenmaps. We also study biharmonic graphs of maps, derive the equation for a function whose graph is a biharmonic hypersurface in a Euclidean space, and give an equivalent formulation of Chen's conjecture on biharmonic hypersurfaces by using the biharmonic graph equation (Theorem 4.1) which paves a way for the analytic study of the conjecture.

People and the Arctic: A Prospectus for Research on the Human Dimensions of the Arctic System (HARC) for the National Science Foundation Arctic System Science Program.

ERIC Educational Resources Information Center

Arctic Research Consortium of the United States, Fairbanks, AK.

The U.S. Global Change Research Program was established in 1990 to develop scientific projections of anticipated impacts of the changing biosphere on humans and social systems. As part of this program, the National Science Foundation created the Arctic System Science Program (ARCSS). This document describes the ARCSS Human Dimensions of the Arctic…

A human-dimensions review of human-wildlife disturbance: A literature review of impacts, frameworks, and management solutions

USGS Publications Warehouse

Cline, Robert; Sexton, Natalie; Stewart, Susan C.

2007-01-01

The following report was prepared for the U.S. Fish and Wildlife Service National Refuge System in support of their Comprehensive Conservation Planning (CCP) efforts by the Policy Analysis and Science Assistance Branch (PASA), Fort Collins Science Center, U.S. Geological Survey. While this document provides a summary of contemporary recreation management literature and methodologies, relevant to the subject of managing wildlife disturbances on national wildlife refuges, this document should be viewed as a starting point for management administrators. This document identifies general issues relating to wildlife disturbance and visitor impacts including a description of disturbance, recreational impacts, related human dimensions applications, management frameworks, and a general summary of management solutions. The section on descriptions of wildlife disturbance and impacts draws heavily from the report entitled 'Managing the Impacts of Visitor Use on Waterbirds -- A Literature Review of Impacts and Mitigation' (DeLong, 2002; Delong and Adamcik, in press) and is referenced in the text. This document is more comprehensive in its review of wildlife response to disturbance. This document is intended to discuss the human-dimensions aspect of wildlife disturbance, summarizing human dimensions and recreation management literature as it applies to this topic.

Individual predictions of eye-movements with dynamic scenes

NASA Astrophysics Data System (ADS)

Barth, Erhardt; Drewes, Jan; Martinetz, Thomas

2003-06-01

We present a model that predicts saccadic eye-movements and can be tuned to a particular human observer who is viewing a dynamic sequence of images. Our work is motivated by applications that involve gaze-contingent interactive displays on which information is displayed as a function of gaze direction. The approach therefore differs from standard approaches in two ways: (1) we deal with dynamic scenes, and (2) we provide means of adapting the model to a particular observer. As an indicator for the degree of saliency we evaluate the intrinsic dimension of the image sequence within a geometric approach implemented by using the structure tensor. Out of these candidate saliency-based locations, the currently attended location is selected according to a strategy found by supervised learning. The data are obtained with an eye-tracker and subjects who view video sequences. The selection algorithm receives candidate locations of current and past frames and a limited history of locations attended in the past. We use a linear mapping that is obtained by minimizing the quadratic difference between the predicted and the actually attended location by gradient descent. Being linear, the learned mapping can be quickly adapted to the individual observer.

Tropical Ecosystems and Ecological Concepts

NASA Astrophysics Data System (ADS)

Osborne, Patrick L.

2000-09-01

Over one third of the earth's terrestrial surface is situated in the tropics, with environments ranging from hot deserts to tropical rain forests. This introductory textbook, aimed at students studying tropical ecology, provides a comprehensive guide to the major tropical biomes and is unique in its balanced coverage of both aquatic and terrestrial systems. The volume considers the human ecological dimension, covering issues such as population growth, urbanization, agriculture and fisheries, natural resource use, and pollution. It is international in scope and addresses global issues such as conservation of biodiversity, climate change, and the concept of ecological sustainability. The text is supported throughout by boxes containing supplementary material on a range of topics and organisms, mathematical concepts and calculations, and is enlivened with clear line diagrams, maps, and photographs. A cross-referenced glossary, extensive bibliography, and comprehensive index are included as further aids to study.

[The nonlinear parameters of interference EMG of two day old human newborns].

PubMed

Voroshilov, A S; Meĭgal, A Iu

2011-01-01

Temporal structure of interference electromyogram (iEMG) was studied in healthy two days old human newborns (n = 76) using the non-linear parameters (correlation dimension, fractal dimension, correlation entropy). It has been found that the non-linear parameters of iEMG were time-dependent because they were decreasing within the first two days of life. Also, these parameters were sensitive to muscle function, because correlation dimension, fractal dimension, and correlation entropy of iEMG in gastrocnemius muscle differed from the other muscles. The non-linear parameters were proven to be independent of the iEMG amplitude. That model of early ontogenesis may be of potential use for investigation of anti-gravitation activity.

Phases and stability of non-uniform black strings

NASA Astrophysics Data System (ADS)

Emparan, Roberto; Luna, Raimon; Martínez, Marina; Suzuki, Ryotaku; Tanabe, Kentaro

2018-05-01

We construct solutions of non-uniform black strings in dimensions from D ≈ 9 all the way up to D = ∞, and investigate their thermodynamics and dynamical stability. Our approach employs the large- D perturbative expansion beyond the leading order, including corrections up to 1 /D 4. Combining both analytical techniques and relatively simple numerical solution of ODEs, we map out the ranges of parameters in which non-uniform black strings exist in each dimension and compute their thermodynamics and quasinormal modes with accuracy. We establish with very good precision the existence of Sorkin's critical dimension and we prove that not only the thermodynamic stability, but also the dynamic stability of the solutions changes at it.

Stroboscobic near-field scanning optical microscopy for 3D mapping of mode profiles of plasmonic nanostructures (Conference Presentation)

NASA Astrophysics Data System (ADS)

Dana, Aykutlu; Ozgur, Erol; Torunoglu, Gamze

2016-09-01

We present a dynamic approach to scanning near field optical microscopy that extends the measurement technique to the third dimension, by strobing the illumination in sync with the cantilever oscillation. Nitrogen vacancy (NV) centers in nanodiamonds placed on cantilever tips are used as stable emitters for emission enhancement. Local field enhancement and modulation of optical density states are mapped in three dimensions based on fluorescence intensity and spectrum changes as the tip is scanned over plasmonic nanostructures. The excitation of NV centers is done using a total internal reflection setup. Using a digital phase locked loop to pulse the excitation in various tip sample separations, 2D slices of fluorescence enhancement can be recorded. Alternatively, a conventional SNOM tip can be used to selectively couple wideband excitation to the collection path, with subdiffraction resolution of 60 nm in x and y and 10 nm in z directions. The approach solves the problem of tip-sample separation stabilization over extended periods of measurement time, required to collect data resolved in emission wavelength and three spatial dimensions. The method can provide a unique way of accessing the three dimensional field and mode profiles of nanophotonics structures.

Domain-wall excitations in the two-dimensional Ising spin glass

NASA Astrophysics Data System (ADS)

Khoshbakht, Hamid; Weigel, Martin

2018-02-01

The Ising spin glass in two dimensions exhibits rich behavior with subtle differences in the scaling for different coupling distributions. We use recently developed mappings to graph-theoretic problems together with highly efficient implementations of combinatorial optimization algorithms to determine exact ground states for systems on square lattices with up to 10 000 ×10 000 spins. While these mappings only work for planar graphs, for example for systems with periodic boundary conditions in at most one direction, we suggest here an iterative windowing technique that allows one to determine ground states for fully periodic samples up to sizes similar to those for the open-periodic case. Based on these techniques, a large number of disorder samples are used together with a careful finite-size scaling analysis to determine the stiffness exponents and domain-wall fractal dimensions with unprecedented accuracy, our best estimates being θ =-0.2793 (3 ) and df=1.273 19 (9 ) for Gaussian couplings. For bimodal disorder, a new uniform sampling algorithm allows us to study the domain-wall fractal dimension, finding df=1.279 (2 ) . Additionally, we also investigate the distributions of ground-state energies, of domain-wall energies, and domain-wall lengths.

Visibility graphs of random scalar fields and spatial data

NASA Astrophysics Data System (ADS)

Lacasa, Lucas; Iacovacci, Jacopo

2017-07-01

We extend the family of visibility algorithms to map scalar fields of arbitrary dimension into graphs, enabling the analysis of spatially extended data structures as networks. We introduce several possible extensions and provide analytical results on the topological properties of the graphs associated to different types of real-valued matrices, which can be understood as the high and low disorder limits of real-valued scalar fields. In particular, we find a closed expression for the degree distribution of these graphs associated to uncorrelated random fields of generic dimension. This result holds independently of the field's marginal distribution and it directly yields a statistical randomness test, applicable in any dimension. We showcase its usefulness by discriminating spatial snapshots of two-dimensional white noise from snapshots of a two-dimensional lattice of diffusively coupled chaotic maps, a system that generates high dimensional spatiotemporal chaos. The range of potential applications of this combinatorial framework includes image processing in engineering, the description of surface growth in material science, soft matter or medicine, and the characterization of potential energy surfaces in chemistry, disordered systems, and high energy physics. An illustration on the applicability of this method for the classification of the different stages involved in carcinogenesis is briefly discussed.

Global terrestrial Human Footprint maps for 1993 and 2009

PubMed Central

Venter, Oscar; Sanderson, Eric W.; Magrach, Ainhoa; Allan, James R.; Beher, Jutta; Jones, Kendall R.; Possingham, Hugh P.; Laurance, William F.; Wood, Peter; Fekete, Balázs M.; Levy, Marc A.; Watson, James E.M.

2016-01-01

Remotely-sensed and bottom-up survey information were compiled on eight variables measuring the direct and indirect human pressures on the environment globally in 1993 and 2009. This represents not only the most current information of its type, but also the first temporally-consistent set of Human Footprint maps. Data on human pressures were acquired or developed for: 1) built environments, 2) population density, 3) electric infrastructure, 4) crop lands, 5) pasture lands, 6) roads, 7) railways, and 8) navigable waterways. Pressures were then overlaid to create the standardized Human Footprint maps for all non-Antarctic land areas. A validation analysis using scored pressures from 3114×1 km2 random sample plots revealed strong agreement with the Human Footprint maps. We anticipate that the Human Footprint maps will find a range of uses as proxies for human disturbance of natural systems. The updated maps should provide an increased understanding of the human pressures that drive macro-ecological patterns, as well as for tracking environmental change and informing conservation science and application. PMID:27552448

SA54. The Structure of Embodied Emotions in Schizophrenia

PubMed Central

Hong, Seok Jin; Snodgress, Matthew A.; Nichols, Heathman S.; Nummenmaa, Lauri; Glerean, Enrico; Park, Sohee

2017-01-01

Abstract Background: Past research suggests a disconnection between experienced emotions and bodily sensations in individuals with schizophrenia (SZ), but mechanisms underlying abnormal embodiment of emotions in SZ are unknown. There might be an overall reduction in emotion-related bodily sensations, but it is also possible that the spatial distribution of bodily sensations associated with emotions may be altered in SZ. We hypothesized the presence of a more coherent underlying structure giving rise to embodied emotions in healthy controls (HC) compared to SZ. Methods: Fifteen SZ and 15 demographically matched HC (bootstrapped from a possible 300 HC) were asked to complete the emBODY task (Nummenmaa et al., 2014). In the emBODY task, participants were asked to shade in where they felt sensations (activation and deactivation) on the outline of a human body when presented with an emotion word. Fourteen emotion words were presented sequentially. From activation and deactivation data, body maps of emotions were generated and 2 separate principal components analyses (PCA) were conducted, one for each group to determine the multivariate structure of embodied emotions. Results: The pattern of principal components for HC differed significantly from that of the SZ group. SZ showed more diffuse components with lesser magnitude than the HC. Moreover, the variance that accounts for these dimensions was significantly reduced for SZ. This suggests anomalous embodied emotion in SZ. In this PCA framework, a particular set of innate constructs is thought to yield the activation and deactivation maps of emotions on the body. Our results imply that the complexity of this set in SZ is highly deviant from that of the HC. Conclusion: Quantitative modeling of the underlying structure of self-reported embodied emotion provided novel insight into altered emotional experience in SZ. Our findings illustrate radically different bodily maps of emotions in SZ compared to HC. Bodily sensations are not only different in intensity but also in where they are felt in SZ. While an important first step, our analysis was exploratory and limited by the small sample size. Future direction includes probing the specific contents of the underlying dimensions that give rise to embodied emotions.

A Human Dimensions Framework: Guidelines for Conducting Social Assessments

Treesearch

Alan D. Bright; H. Ken Cordell; Anne P. Hoover; Michael A Tarrant

2003-01-01

This paper provides a framework and guidelines for identifying and organizing human dimension information for use in forest planning. It synthesizes concepts from a variety of social science disciplines and connects them with measurable indicators for use in analysis and reporting. Suggestions of analytical approaches and sources of data for employment of the...

Development Education and Multi-Ethnic Education: Some Tensions. Development Education Paper No. 21.

ERIC Educational Resources Information Center

Storm, Michael

The document examines the relationships between multi-ethnic and development education in Great Britain. Multi-ethnic education, initially with a national focus, has a global dimension, and development education, initially with a global focus, has a national and even local dimension. A common interest in human diversity and human inequalities…

The human dimensions of urban greenways: planning for recreation and related experiences

Treesearch

Paul H. Gobster; Lynne M. Westpahl

2004-01-01

In this paper, we summarize findings from a series of interrelated studies that examine an urban greenway, the 150 mile Chicago River corridor in Chicago, USA, from multiple perspectives, stakeholder viewpoints, and methodological techniques. Six interdependent "human dimensions" of greenways are identified in the studies: cleanliness, naturalness, aesthetics...

Homosexuals' and Lesbians' Philosophies of Human Nature.

ERIC Educational Resources Information Center

Weller, Leonard; Benozio, Motti

1987-01-01

Compared 57 homosexual men and 45 lesbians on six dimensions of beliefs about human nature. On only one dimension was significant difference found: lesbians saw people as more altruistic and less selfish than did homosexual men. Findings are consistent with the few personality studies which report no differences between homosexuals and lesbians.…

Political and Cultural Dimensions of Organizing Learning around Funds of Knowledge

ERIC Educational Resources Information Center

Ares, Nancy

2010-01-01

O'Connor and Penuel (2010) argue that viewing research in education as a human science requires explicit attention to social, cultural, historical, and institutional dimensions of human activity, to the agency of participants in learning research, and to the importance of incorporating "emic" perspectives that shift the voice of the…

The normative dimensions of extending the human lifespan by age-related biomedical innovations.

PubMed

Ehni, Hans-Joerg; Marckmann, Georg

2008-10-01

The current normative debate on age-related biomedical innovations and the extension of the human lifespan has important shortcomings. Mainly, the complexity of the different normative dimensions relevant for ethical and/or juridicial norms is not fully developed and the normative quality of teleological and deontological arguments is not properly distinguished. This article addresses some of these shortcomings and develops the outline of a more comprehensive normative framework covering all relevant dimensions. Such a frame necessarily has to include conceptions of a good life on the individual and societal levels. Furthermore, as a third dimension, a model for the access to and the just distribution of age-related biomedical innovations and technologies extending the human lifespan will be developed. It is argued that such a model has to include the different levels of the general philosophical theories of distributive justice, including social rights and theories of just health care. Furthermore, it has to show how these theories can be applied to the problem area of aging and extending the human lifespan.

Dimension- and space-based intertrial effects in visual pop-out search: modulation by task demands for focal-attentional processing.

PubMed

Krummenacher, Joseph; Müller, Hermann J; Zehetleitner, Michael; Geyer, Thomas

2009-03-01

Two experiments compared reaction times (RTs) in visual search for singleton feature targets defined, variably across trials, in either the color or the orientation dimension. Experiment 1 required observers to simply discern target presence versus absence (simple-detection task); Experiment 2 required them to respond to a detection-irrelevant form attribute of the target (compound-search task). Experiment 1 revealed a marked dimensional intertrial effect of 34 ms for an target defined in a changed versus a repeated dimension, and an intertrial target distance effect, with an 4-ms increase in RTs (per unit of distance) as the separation of the current relative to the preceding target increased. Conversely, in Experiment 2, the dimension change effect was markedly reduced (11 ms), while the intertrial target distance effect was markedly increased (11 ms per unit of distance). The results suggest that dimension change/repetition effects are modulated by the amount of attentional focusing required by the task, with space-based attention altering the integration of dimension-specific feature contrast signals at the level of the overall-saliency map.

Human cDNA mapping using fluorescence in situ hybridization. Final progress report, April 1, 1994--July 31, 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

Korenberg, J.R.

The ultimate goal of this research is to generate and apply novel technologies to speed completion and integration of the human genome map and sequence with biomedical problems. To do this, techniques were developed and genome-wide resources generated. This includes a genome-wide Mapped and Integrated BAC/PAC Resource that has been used for gene finding, map completion and anchoring, breakpoint definition and sequencing. In the last period of the grant, the Human Mapped BAC/PAC Resource was also applied to determine regions of human variation and to develop a novel paradigm of primate evolution through to humans. Further, in order to moremore » rapidly evaluate animal models of human disease, a BAC Map of the mouse was generated in collaboration with the MTI Genome Center, Dr. Bruce Birren.« less

Cultural Dimensions of Military Training

DTIC Science & Technology

2014-06-13

perceptual and behavioral dimensions of the human terrain of any military or military-supported mission. Its principal missions are curriculum design...CULTURAL DIMENSIONS OF MILITARY TRAINING A thesis presented to the Faculty of the U.S. Army Command and General Staff... Dimensions of Military Training 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) LTC Acasandrei Nicolae, Romania

a New Ontological Perspective for Integration of Social and Physical Environments: Disability and Rehabilitation Context

NASA Astrophysics Data System (ADS)

Gharebaghi, Amin; Abolfazl Mostafavi, Mir

2016-06-01

Social dimension of environment is an important aspect that should be reflected in research works related to studying the interactions between human and the environment. However, this dimension is usually neglected when representing the environment in geographic information systems for different applications. For instance, disability as a result of the interaction between human and environment is influenced by social and physical dimensions of environment. Although, this aspect is highlighted in most conceptual disability models by defining various taxonomies of the environment, from ontological perspective justifying and connecting social dimension to the physical dimension of the environment is not clearly determined. Integrating social dimension of the environment with its physical dimension for disability studies is a challenging task, which is the main objective of the present study. Here, we review some of the disability models and their perspective about classifying the environment. Then, from ontological perspective, their limitations are discussed and a new approach for the classification of concepts form the environment is presented. This approach facilitates and simplifies integration of social dimension in ontologies for more effective assessment of disability issue in Geographic Information System.

Strategic Leadership

ERIC Educational Resources Information Center

Davies, Barbara; Davies, Brent

2004-01-01

This article explores the nature of strategic leadership and assesses whether a framework can be established to map the dimensions of strategic leadership. In particular it establishes a model which outlines both the organizational abilities and the individual characteristics of strategic leaders.

Optimization of the first dimension for separation by two-dimensional gel electrophoresis of basic proteins from human brain tissue.

PubMed

Pennington, Kyla; McGregor, Emma; Beasley, Clare L; Everall, Ian; Cotter, David; Dunn, Michael J

2004-01-01

A major cause of poor resolution in the alkaline pH range of two-dimensional electrophoresis (2-DE) gels is unsatisfactory separation of basic proteins in the first dimension. We have compared methods for the separation of basic proteins in the isoelectric focusing dimension of human brain proteins. The combined use of anodic cup-loading and the hydroxyethyldisulphide containing solution (DeStreak) produced better resolution in both analytical and micropreparative protein loaded 2-DE gels than the other methods investigated.

Control theory based airfoil design using the Euler equations

NASA Technical Reports Server (NTRS)

Jameson, Antony; Reuther, James

1994-01-01

This paper describes the implementation of optimization techniques based on control theory for airfoil design. In our previous work it was shown that control theory could be employed to devise effective optimization procedures for two-dimensional profiles by using the potential flow equation with either a conformal mapping or a general coordinate system. The goal of our present work is to extend the development to treat the Euler equations in two-dimensions by procedures that can readily be generalized to treat complex shapes in three-dimensions. Therefore, we have developed methods which can address airfoil design through either an analytic mapping or an arbitrary grid perturbation method applied to a finite volume discretization of the Euler equations. Here the control law serves to provide computationally inexpensive gradient information to a standard numerical optimization method. Results are presented for both the inverse problem and drag minimization problem.

Pseudochaotic dynamics near global periodicity

NASA Astrophysics Data System (ADS)

Fan, Rong; Zaslavsky, George M.

2007-09-01

In this paper, we study a piecewise linear version of kicked oscillator model: saw-tooth map. A special case of global periodicity, in which every phase point belongs to a periodic orbit, is presented. With few analytic results known for the corresponding map on torus, we numerically investigate transport properties and statistical behavior of Poincaré recurrence time in two cases of deviation from global periodicity. A non-KAM behavior of the system, as well as subdiffusion and superdiffusion, are observed through numerical simulations. Statistics of Poincaré recurrences shows Kac lemma is valid in the system and there is a relation between the transport exponent and the Poincaré recurrence exponent. We also perform careful numerical computation of capacity, information and correlation dimensions of the so-called exceptional set in both cases. Our results show that the fractal dimension of the exceptional set is strictly less than 2 and that the fractal structures are unifractal rather than multifractal.

Analysis of Resting-State fMRI Topological Graph Theory Properties in Methamphetamine Drug Users Applying Box-Counting Fractal Dimension.

PubMed

Siyah Mansoory, Meysam; Oghabian, Mohammad Ali; Jafari, Amir Homayoun; Shahbabaie, Alireza

2017-01-01

Graph theoretical analysis of functional Magnetic Resonance Imaging (fMRI) data has provided new measures of mapping human brain in vivo. Of all methods to measure the functional connectivity between regions, Linear Correlation (LC) calculation of activity time series of the brain regions as a linear measure is considered the most ubiquitous one. The strength of the dependence obligatory for graph construction and analysis is consistently underestimated by LC, because not all the bivariate distributions, but only the marginals are Gaussian. In a number of studies, Mutual Information (MI) has been employed, as a similarity measure between each two time series of the brain regions, a pure nonlinear measure. Owing to the complex fractal organization of the brain indicating self-similarity, more information on the brain can be revealed by fMRI Fractal Dimension (FD) analysis. In the present paper, Box-Counting Fractal Dimension (BCFD) is introduced for graph theoretical analysis of fMRI data in 17 methamphetamine drug users and 18 normal controls. Then, BCFD performance was evaluated compared to those of LC and MI methods. Moreover, the global topological graph properties of the brain networks inclusive of global efficiency, clustering coefficient and characteristic path length in addict subjects were investigated too. Compared to normal subjects by using statistical tests (P<0.05), topological graph properties were postulated to be disrupted significantly during the resting-state fMRI. Based on the results, analyzing the graph topological properties (representing the brain networks) based on BCFD is a more reliable method than LC and MI.

Animated axial surface mapping: The multimedia companion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hook, S.C.; Shaw, J.H.; Suppe, J.

1995-09-01

This newly expanded version of AAPG`s first DataShare Disk brings to life the concepts and applications of a new method of structural trend analysis. Through the dynamic use of color, sound, animation, and humor, this multimedia companion to the May 1994 article on Axial Surface Mapping introduces the reader (or viewer) to the concepts of rigid-block translation, fault-bend folding, and axial surface mapping. Animated models of growing fault-bend folds allow the viewer to see in four dimensions. The axial surface map shows the horizontal plane; the folding lines show depth planes; and the animations show the structure and its two-dimensionalmore » map changing with time and increasing slip. The animations create theoretical map patterns under varying, but controlled conditions that can be compared to axial surface maps from real data. The model patterns are then used to interpret seismic data and axial surface maps from a producing gas field in offshore California and from an exploration play in Pennsylvania.« less

Characterizing semantic mappings adaptation via biomedical KOS evolution: a case study investigating SNOMED CT and ICD.

PubMed

Dos Reis, Julio Cesar; Pruski, Cédric; Da Silveira, Marcos; Reynaud-Delaître, Chantal

2013-01-01

Mappings established between Knowledge Organization Systems (KOS) increase semantic interoperability between biomedical information systems. However, biomedical knowledge is highly dynamic and changes affecting KOS entities can potentially invalidate part or the totality of existing mappings. Understanding how mappings evolve and what the impacts of KOS evolution on mappings are is therefore crucial for the definition of an automatic approach to maintain mappings valid and up-to-date over time. In this article, we study variations of a specific KOS complex change (split) for two biomedical KOS (SNOMED CT and ICD-9-CM) through a rigorous method of investigation for identifying and refining complex changes, and for selecting representative cases. We empirically analyze and explain their influence on the evolution of associated mappings. Results point out the importance of considering various dimensions of the information described in KOS, like the semantic structure of concepts, the set of relevant information used to define the mappings and the change operations interfering with this set of information.

Characterizing Semantic Mappings Adaptation via Biomedical KOS Evolution: A Case Study Investigating SNOMED CT and ICD

PubMed Central

Reis, Julio Cesar Dos; Pruski, Cédric; Da Silveira, Marcos; Reynaud-Delaître, Chantal

2013-01-01

Mappings established between Knowledge Organization Systems (KOS) increase semantic interoperability between biomedical information systems. However, biomedical knowledge is highly dynamic and changes affecting KOS entities can potentially invalidate part or the totality of existing mappings. Understanding how mappings evolve and what the impacts of KOS evolution on mappings are is therefore crucial for the definition of an automatic approach to maintain mappings valid and up-to-date over time. In this article, we study variations of a specific KOS complex change (split) for two biomedical KOS (SNOMED CT and ICD-9-CM) through a rigorous method of investigation for identifying and refining complex changes, and for selecting representative cases. We empirically analyze and explain their influence on the evolution of associated mappings. Results point out the importance of considering various dimensions of the information described in KOS, like the semantic structure of concepts, the set of relevant information used to define the mappings and the change operations interfering with this set of information. PMID:24551341

Two-dimensional liquid chromatography consisting of twelve second-dimension columns for comprehensive analysis of intact proteins.

PubMed

Ren, Jiangtao; Beckner, Matthew A; Lynch, Kyle B; Chen, Huang; Zhu, Zaifang; Yang, Yu; Chen, Apeng; Qiao, Zhenzhen; Liu, Shaorong; Lu, Joann J

2018-05-15

A comprehensive two-dimensional liquid chromatography (LCxLC) system consisting of twelve columns in the second dimension was developed for comprehensive analysis of intact proteins in complex biological samples. The system consisted of an ion-exchange column in the first dimension and the twelve reverse-phase columns in the second dimension; all thirteen columns were monolithic and prepared inside 250 µm i.d. capillaries. These columns were assembled together through the use of three valves and an innovative configuration. The effluent from the first dimension was continuously fractionated and sequentially transferred into the twelve second-dimension columns, while the second-dimension separations were carried out in a series of batches (six columns per batch). This LCxLC system was tested first using standard proteins followed by real-world samples from E. coli. Baseline separation was observed for eleven standard proteins and hundreds of peaks were observed for the real-world sample analysis. Two-dimensional liquid chromatography, often considered as an effective tool for mapping proteins, is seen as laborious and time-consuming when configured offline. Our online LCxLC system with increased second-dimension columns promises to provide a solution to overcome these hindrances. Copyright © 2018 Elsevier B.V. All rights reserved.

Dimensions of lay health worker programmes: results of a scoping study and production of a descriptive framework.

PubMed

South, Jane; Meah, Angela; Bagnall, Anne-Marie; Jones, Rebecca

2013-03-01

Approaches that engage and support lay health workers in the delivery of health improvement activities have been widely applied across different health issues and populations. The lack of a common terminology, inconsistency in the use of role descriptors and poor indexing of lay health worker roles are all barriers to the development of a shared evidence base for lay health worker interventions. The aim of the paper is to report results from a scoping study of approaches to involve lay people in public health roles and to present a framework for categorisation of the different dimensions of lay health worker programmes. Our scoping study comprised a systematic scoping review to map the literature on lay health worker interventions and to identify role dimensions and common models. The review, which was limited to interventions relevant to UK public health priorities, covered a total of 224 publications. The scoping study also drew on experiential evidence from UK practice. Research-based and practice-based evidence confirmed the variety of role descriptors in use and the complexity of role dimensions. Five common models that define the primary role of the lay health worker were identified from the literature. A framework was later developed that grouped features of lay health worker programmes into four dimensions: intervention, role, professional support/service and the community. More account needs to be taken of the variations that occur between lay health worker programmes. This framework, with the mapping of key categories of difference, may enable better description of lay health worker programmes, which will in turn assist in building a shared evidence base. More research is needed to examine the transferability of the framework within different contexts.

Study on the Distribution of Geological Hazards Based on Fractal Characteristics - a Case Study of Dachuan District

NASA Astrophysics Data System (ADS)

Wang, X.; Liu, H.; Yao, K.; Wei, Y.

2018-04-01

It is a complicated process to analyze the cause of geological hazard. Through the analysis function of GIS software, 250 landslides were randomly selected from 395 landslide hazards in the study area, superimposed with the types of landforms, annual rainfall and vegetation coverage respectively. It used box dimension method of fractal dimension theory to study the fractal characteristics of spatial distribution of landslide disasters in Dachuan district, and analyse the statistical results. Research findings showed that the The fractal dimension of the landslides in the Dachuan area is 0.9114, the correlation coefficient is 0.9627, and it has high autocorrelation. Zoning statistics according to various natural factors, the fractal dimension between landslide hazard points and deep hill, middle hill area is strong as well as the area whose average annual rainfall is 1050 mm-1250 mm and vegetation coverage is 30 %-60 %. Superposition of the potential hazard distribution map of single influence factors to get the potential hazard zoning of landslides in the area. Verifying the potential hazard zoning map of the potential landslides with 145 remaining disaster points, among them, there are 74 landslide hazard points in high risk area, accounting for 51.03 % of the total. There are 59 landslides in the middle risk area, accounting for 40.69 % of the total, and 12 in the low risk area, accounting for 8.28 % of the total. The matching degree of the verifying result and the potential hazard zoning is high. Therefore, the fractal dimension value divided the degree of geological disaster susceptibility can be described the influence degree of each influence factor to geological disaster point more intuitively, it also can divide potential disaster risk areas and provide visual data support for effective management of geological disasters.

Affective State Level Recognition in Naturalistic Facial and Vocal Expressions.

PubMed

Meng, Hongying; Bianchi-Berthouze, Nadia

2014-03-01

Naturalistic affective expressions change at a rate much slower than the typical rate at which video or audio is recorded. This increases the probability that consecutive recorded instants of expressions represent the same affective content. In this paper, we exploit such a relationship to improve the recognition performance of continuous naturalistic affective expressions. Using datasets of naturalistic affective expressions (AVEC 2011 audio and video dataset, PAINFUL video dataset) continuously labeled over time and over different dimensions, we analyze the transitions between levels of those dimensions (e.g., transitions in pain intensity level). We use an information theory approach to show that the transitions occur very slowly and hence suggest modeling them as first-order Markov models. The dimension levels are considered to be the hidden states in the Hidden Markov Model (HMM) framework. Their discrete transition and emission matrices are trained by using the labels provided with the training set. The recognition problem is converted into a best path-finding problem to obtain the best hidden states sequence in HMMs. This is a key difference from previous use of HMMs as classifiers. Modeling of the transitions between dimension levels is integrated in a multistage approach, where the first level performs a mapping between the affective expression features and a soft decision value (e.g., an affective dimension level), and further classification stages are modeled as HMMs that refine that mapping by taking into account the temporal relationships between the output decision labels. The experimental results for each of the unimodal datasets show overall performance to be significantly above that of a standard classification system that does not take into account temporal relationships. In particular, the results on the AVEC 2011 audio dataset outperform all other systems presented at the international competition.

Modeling and simulating human teamwork behaviors using intelligent agents

NASA Astrophysics Data System (ADS)

Fan, Xiaocong; Yen, John

2004-12-01

Among researchers in multi-agent systems there has been growing interest in using intelligent agents to model and simulate human teamwork behaviors. Teamwork modeling is important for training humans in gaining collaborative skills, for supporting humans in making critical decisions by proactively gathering, fusing, and sharing information, and for building coherent teams with both humans and agents working effectively on intelligence-intensive problems. Teamwork modeling is also challenging because the research has spanned diverse disciplines from business management to cognitive science, human discourse, and distributed artificial intelligence. This article presents an extensive, but not exhaustive, list of work in the field, where the taxonomy is organized along two main dimensions: team social structure and social behaviors. Along the dimension of social structure, we consider agent-only teams and mixed human-agent teams. Along the dimension of social behaviors, we consider collaborative behaviors, communicative behaviors, helping behaviors, and the underpinning of effective teamwork-shared mental models. The contribution of this article is that it presents an organizational framework for analyzing a variety of teamwork simulation systems and for further studying simulated teamwork behaviors.

A methodological approach and framework for sustainability assessment in NGO-implemented primary health care programs.

PubMed

Sarriot, Eric G; Winch, Peter J; Ryan, Leo J; Bowie, Janice; Kouletio, Michelle; Swedberg, Eric; LeBan, Karen; Edison, Jay; Welch, Rikki; Pacqué, Michel C

2004-01-01

An estimated 10.8 million children under 5 continue to die each year in developing countries from causes easily treatable or preventable. Non governmental organizations (NGOs) are frontline implementers of low-cost and effective child health interventions, but their progress toward sustainable child health gains is a challenge to evaluate. This paper presents the Child Survival Sustainability Assessment (CSSA) methodology--a framework and process--to map progress towards sustainable child health from the community level and upward. The CSSA was developed with NGOs through a participatory process of research and dialogue. Commitment to sustainability requires a systematic and systemic consideration of human, social and organizational processes beyond a purely biomedical perspective. The CSSA is organized around three interrelated dimensions of evaluation: (1) health and health services; (2) capacity and viability of local organizations; (3) capacity of the community in its social ecological context. The CSSA uses a participatory, action-planning process, engaging a 'local system' of stakeholders in the contextual definition of objectives and indicators. Improved conditions measured in the three dimensions correspond to progress toward a sustainable health situation for the population. This framework opens new opportunities for evaluation and research design and places sustainability at the center of primary health care programming.

Spatial Statistics of the Clark County Parcel Map, Trial Geotechnical Models, and Effects on Ground Motions in Las Vegas Valley

NASA Astrophysics Data System (ADS)

Savran, W. H.; Louie, J. N.; Pullammanappallil, S.; Pancha, A.

2011-12-01

When deterministically modeling the propagation of seismic waves, shallow shear-wave velocity plays a crucial role in predicting shaking effects such as peak ground velocity (PGV). The Clark County Parcel Map provides us with a data set of geotechnical velocities in Las Vegas Valley, at an unprecedented level of detail. Las Vegas Valley is a basin with similar geologic properties to some areas of Southern California. We analyze elementary spatial statistical properties of the Parcel Map, along with calculating its spatial variability. We then investigate these spatial statistics from the PGV results computed from two geotechnical models that incorporate the Parcel Map as parameters. Plotting a histogram of the Parcel Map 30-meter depth-averaged shear velocity (Vs30) values shows the data to approximately fit a bimodal normal distribution with μ1 = 400 m/s, σ1 = 76 m/s, μ2 = 790 m/s, σ2 = 149 m/s, and p = 0.49., where μ is the mean, σ is standard deviation, and p is the probability mixing factor for the bimodal distribution. Based on plots of spatial power spectra, the Parcel Map appears to be fractal over the second and third decades, in kilometers. The spatial spectra possess the same fractal dimension in the N-S and the E-W directions, indicating isotropic scale invariance. We configured finite-difference wave propagation models at 0.5 Hz with LLNL's E3D code, utilizing the Parcel Map as input parameters to compute a PGV data set from a scenario earthquake (Black Hills M6.5). The resulting PGV is fractal over the same spatial frequencies as the Vs30 data sets associated with their respective models. The fractal dimension is systematically lower in all of the PGV maps as opposed to the Vs30 maps, showing that the PGV maps are richer in higher spatial frequencies. This is potentially caused by a lens focusing effects on seismic waves due to spatial heterogeneity in site conditions.

Topic maps for exploring nosological, lexical, semantic and HL7 structures for clinical data.

PubMed

Paterson, Grace I; Grant, Andrew M; Soroka, Steven D

2008-12-01

A topic map is implemented for learning about clinical data associated with a hospital stay for patients diagnosed with chronic kidney disease, diabetes and hypertension. The question posed is: how might a topic map help bridge perspectival differences among communities of practice and help make commensurable the different classifications they use? The knowledge layer of the topic map was generated from existing ontological relationships in nosological, lexical, semantic and HL7 boundary objects. Discharge summaries, patient charts and clinical data warehouse entries rectified the clinical knowledge used in practice. These clinical data were normalized to HL7 Clinical Document Architecture (CDA) markup standard and stored in the Clinical Document Repository. Each CDA entry was given a subject identifier and linked with the topic map. The ability of topic maps to function as the infostructure ;glue' is assessed using dimensions of semantic interoperability and commensurability.

Challenges and complications in neighborhood mapping: from neighborhood concept to operationalization

NASA Astrophysics Data System (ADS)

Deng, Yongxin

2016-07-01

This paper examines complications in neighborhood mapping and corresponding challenges for the GIS community, taking both a conceptual and a methodological perspective. It focuses on the social and spatial dimensions of the neighborhood concept and highlights their relationship in neighborhood mapping. Following a brief summary of neighborhood definitions, five interwoven factors are identified to be origins of neighborhood mapping difficulties: conceptual vagueness, uncertainty of various sources, GIS representation, scale, and neighborhood homogeneity or continuity. Existing neighborhood mapping methods are grouped into six categories to be assessed: perception based, physically based, inference based, preexisting, aggregated, and automated. Mapping practices in various neighborhood-related disciplines and applications are cited as examples to demonstrate how the methods work, as well as how they should be evaluated. A few mapping strategies for the improvement of neighborhood mapping are prescribed from a GIS perspective: documenting simplifications employed in the mapping procedure, addressing uncertainty sources, developing new data solutions, and integrating complementary mapping methods. Incorporation of high-resolution data and introduction of more GIS ideas and methods (such as fuzzy logic) are identified to be future opportunities.

Influence of pansharpening techniques in obtaining accurate vegetation thematic maps

NASA Astrophysics Data System (ADS)

Ibarrola-Ulzurrun, Edurne; Gonzalo-Martin, Consuelo; Marcello-Ruiz, Javier

2016-10-01

In last decades, there have been a decline in natural resources, becoming important to develop reliable methodologies for their management. The appearance of very high resolution sensors has offered a practical and cost-effective means for a good environmental management. In this context, improvements are needed for obtaining higher quality of the information available in order to get reliable classified images. Thus, pansharpening enhances the spatial resolution of the multispectral band by incorporating information from the panchromatic image. The main goal in the study is to implement pixel and object-based classification techniques applied to the fused imagery using different pansharpening algorithms and the evaluation of thematic maps generated that serve to obtain accurate information for the conservation of natural resources. A vulnerable heterogenic ecosystem from Canary Islands (Spain) was chosen, Teide National Park, and Worldview-2 high resolution imagery was employed. The classes considered of interest were set by the National Park conservation managers. 7 pansharpening techniques (GS, FIHS, HCS, MTF based, Wavelet `à trous' and Weighted Wavelet `à trous' through Fractal Dimension Maps) were chosen in order to improve the data quality with the goal to analyze the vegetation classes. Next, different classification algorithms were applied at pixel-based and object-based approach, moreover, an accuracy assessment of the different thematic maps obtained were performed. The highest classification accuracy was obtained applying Support Vector Machine classifier at object-based approach in the Weighted Wavelet `à trous' through Fractal Dimension Maps fused image. Finally, highlight the difficulty of the classification in Teide ecosystem due to the heterogeneity and the small size of the species. Thus, it is important to obtain accurate thematic maps for further studies in the management and conservation of natural resources.

Effects of Butyltins (BTs) on Mitogen-Activated-Protein Kinase Kinase Kinase (MAP3K) and Ras Activity in Human Natural Killer Cells

PubMed Central

Celada, Lindsay J.; Whalen, Margaret M.

2013-01-01

Butyltins (BTs) contaminate the environment and are found in human blood. BTs, tributyltin (TBT) and dibutyltin (DBT), diminish the cytotoxic function and levels of key proteins of human natural killer (NK) cells. NK cells are an initial immune defense against tumors, virally-infected cells and antibody-coated cells and thus critical to human health. The signaling pathways that regulate NK cell functions include mitogen-activated protein kinases (MAPKs). Studies have shown that exposure to BTs leads to the activation of specific MAPKs and MAPK kinases (MAP2Ks) in human NK cells. MAP2K kinases (MAP3Ks) are upstream activators of MAP2Ks, which then activate MAPKs. The current study examined if BT-induced activation of MAP3Ks was responsible for MAP2K and thus, MAPK activation. This study examines the effects of TBT and DBT on the total levels of two MAP3Ks, c-Raf and ASK1, as well as activating and inhibitory phosphorylation sites on these MAP3Ks. In addition, the immediate upstream activator of c-Raf, Ras, was examined for BT-induced alterations. Our results show significant activation of the MAP3K, c-Raf, in human NK cells within 10 minutes of TBT exposure and the MAP3K, ASK1, after one hour exposures to TBT. In addition, our results suggest that both TBT and DBT are impacting the regulation of c-Raf. PMID:24038145

Beyond rankings: using cognitive mapping to understand what health care journals represent.

PubMed

Shewchuk, Richard M; O'connor, Stephen J; Williams, Eric S; Savage, Grant T

2006-03-01

Studies of journal ratings are often controversial. Indices, including impact factors, acceptance rates, expert opinions, and ratings of knowledge, relevance, and quality have been used to organize journals hierarchically. While there may be some validity in consensus rankings, it is unclear what purpose is actually achieved by these endeavors. Impact factors probably help researchers identify authoritative journals, but other rankings likely indicate little more than institutionalized perceptions of prestige. Ranking schema used to derive evaluative judgments do not provide information about the organization of journals from the perspective of substantive content, emphasis, or targeted audience. A cognitive mapping approach that examines how health care management faculty members represent their perceptions of North American health care-oriented journals is presented as an alternative. A card-sort task and importance rating scale was mailed to faculty of North American health management programs who participated in a previous journal ranking study conducted by the authors. Completed assessments were returned from 147 respondents for a response rate of 39%. Multidimensional scaling and hierarchical cluster analyses of data provided a three-dimensional, seven cluster map that illustrates the perceived similarities of journals. Dimension I contrasts Applied Management Practice with Health Policy journals. Dimension II contrasts specific domain with broad-based research journals. Dimension III contrasts finance-oriented with delivery-oriented journals. The seven clusters of perceptually similar journals were weighted in terms of respondent defined importance ascribed to each journal within a cluster. This framework supplements ratings by providing insight about how journals are cognitively organized by scholars.

The Organizational and Human Dimensions of Successful Mentoring Programs and Relationships. Perspectives in Mentoring.

ERIC Educational Resources Information Center

Kochan, Frances K., Ed.

This collection of papers examines mentoring in a variety of settings. The 17 papers are: (1) "The Organizational and Human Dimensions of Successful Mentoring Across Diverse Settings" (Frances K. Kochan); (2) "Parents Mentoring Parents for School Success" (Nathan T. Avani); (3) "Project Nia (Purpose): A University/School Partnership to Enhance…

A map for heavy inertial particles in fluid flows

NASA Astrophysics Data System (ADS)

Vilela, Rafael D.; de Oliveira, Vitor M.

2017-06-01

We introduce a map which reproduces qualitatively many fundamental properties of the dynamics of heavy particles in fluid flows. These include a uniform rate of decrease of volume in phase space, a slow-manifold effective dynamics when the single parameter s (analogous of the Stokes number) approaches zero, the possibility of fold caustics in the "velocity field", and a minimum, as a function of s, of the Lyapunov (Kaplan-Yorke) dimension of the attractor where particles accumulate.

Use of space-time models to investigate the stability of patterns of disease.

PubMed

Abellan, Juan Jose; Richardson, Sylvia; Best, Nicky

2008-08-01

The use of Bayesian hierarchical spatial models has become widespread in disease mapping and ecologic studies of health-environment associations. In this type of study, the data are typically aggregated over an extensive time period, thus neglecting the time dimension. The output of purely spatial disease mapping studies is therefore the average spatial pattern of risk over the period analyzed, but the results do not inform about, for example, whether a high average risk was sustained over time or changed over time. We investigated how including the time dimension in disease-mapping models strengthens the epidemiologic interpretation of the overall pattern of risk. We discuss a class of Bayesian hierarchical models that simultaneously characterize and estimate the stable spatial and temporal patterns as well as departures from these stable components. We show how useful rules for classifying areas as stable can be constructed based on the posterior distribution of the space-time interactions. We carry out a simulation study to investigate the sensitivity and specificity of the decision rules we propose, and we illustrate our approach in a case study of congenital anomalies in England. Our results confirm that extending hierarchical disease-mapping models to models that simultaneously consider space and time leads to a number of benefits in terms of interpretation and potential for detection of localized excesses.

Memory matters: influence from a cognitive map on animal space use.

PubMed

Gautestad, Arild O

2011-10-21

A vertebrate individual's cognitive map provides a capacity for site fidelity and long-distance returns to favorable patches. Fractal-geometrical analysis of individual space use based on collection of telemetry fixes makes it possible to verify the influence of a cognitive map on the spatial scatter of habitat use and also to what extent space use has been of a scale-specific versus a scale-free kind. This approach rests on a statistical mechanical level of system abstraction, where micro-scale details of behavioral interactions are coarse-grained to macro-scale observables like the fractal dimension of space use. In this manner, the magnitude of the fractal dimension becomes a proxy variable for distinguishing between main classes of habitat exploration and site fidelity, like memory-less (Markovian) Brownian motion and Levy walk and memory-enhanced space use like Multi-scaled Random Walk (MRW). In this paper previous analyses are extended by exploring MRW simulations under three scenarios: (1) central place foraging, (2) behavioral adaptation to resource depletion (avoidance of latest visited locations) and (3) transition from MRW towards Levy walk by narrowing memory capacity to a trailing time window. A generalized statistical-mechanical theory with the power to model cognitive map influence on individual space use will be important for statistical analyses of animal habitat preferences and the mechanics behind site fidelity and home ranges. Copyright © 2011 Elsevier Ltd. All rights reserved.

Gamma-Ray imaging for nuclear security and safety: Towards 3-D gamma-ray vision

NASA Astrophysics Data System (ADS)

Vetter, Kai; Barnowksi, Ross; Haefner, Andrew; Joshi, Tenzing H. Y.; Pavlovsky, Ryan; Quiter, Brian J.

2018-01-01

The development of portable gamma-ray imaging instruments in combination with the recent advances in sensor and related computer vision technologies enable unprecedented capabilities in the detection, localization, and mapping of radiological and nuclear materials in complex environments relevant for nuclear security and safety. Though multi-modal imaging has been established in medicine and biomedical imaging for some time, the potential of multi-modal data fusion for radiological localization and mapping problems in complex indoor and outdoor environments remains to be explored in detail. In contrast to the well-defined settings in medical or biological imaging associated with small field-of-view and well-constrained extension of the radiation field, in many radiological search and mapping scenarios, the radiation fields are not constrained and objects and sources are not necessarily known prior to the measurement. The ability to fuse radiological with contextual or scene data in three dimensions, in analog to radiological and functional imaging with anatomical fusion in medicine, provides new capabilities enhancing image clarity, context, quantitative estimates, and visualization of the data products. We have developed new means to register and fuse gamma-ray imaging with contextual data from portable or moving platforms. These developments enhance detection and mapping capabilities as well as provide unprecedented visualization of complex radiation fields, moving us one step closer to the realization of gamma-ray vision in three dimensions.

Development of the "Highly Sensitive Dog" questionnaire to evaluate the personality dimension "Sensory Processing Sensitivity" in dogs.

PubMed

Braem, Maya; Asher, Lucy; Furrer, Sibylle; Lechner, Isabel; Würbel, Hanno; Melotti, Luca

2017-01-01

In humans, the personality dimension 'sensory processing sensitivity (SPS)', also referred to as "high sensitivity", involves deeper processing of sensory information, which can be associated with physiological and behavioral overarousal. However, it has not been studied up to now whether this dimension also exists in other species. SPS can influence how people perceive the environment and how this affects them, thus a similar dimension in animals would be highly relevant with respect to animal welfare. We therefore explored whether SPS translates to dogs, one of the primary model species in personality research. A 32-item questionnaire to assess the "highly sensitive dog score" (HSD-s) was developed based on the "highly sensitive person" (HSP) questionnaire. A large-scale, international online survey was conducted, including the HSD questionnaire, as well as questions on fearfulness, neuroticism, "demographic" (e.g. dog sex, age, weight; age at adoption, etc.) and "human" factors (e.g. owner age, sex, profession, communication style, etc.), and the HSP questionnaire. Data were analyzed using linear mixed effect models with forward stepwise selection to test prediction of HSD-s by the above-mentioned factors, with country of residence and dog breed treated as random effects. A total of 3647 questionnaires were fully completed. HSD-, fearfulness, neuroticism and HSP-scores showed good internal consistencies, and HSD-s only moderately correlated with fearfulness and neuroticism scores, paralleling previous findings in humans. Intra- (N = 447) and inter-rater (N = 120) reliabilities were good. Demographic and human factors, including HSP score, explained only a small amount of the variance of HSD-s. A PCA analysis identified three subtraits of SPS, comparable to human findings. Overall, the measured personality dimension in dogs showed good internal consistency, partial independence from fearfulness and neuroticism, and good intra- and inter-rater reliability, indicating good construct validity of the HSD questionnaire. Human and demographic factors only marginally affected the HSD-s suggesting that, as hypothesized for human SPS, a genetic basis may underlie this dimension within the dog species.

Investigating emotional contagion in dogs (Canis familiaris) to emotional sounds of humans and conspecifics.

PubMed

Huber, Annika; Barber, Anjuli L A; Faragó, Tamás; Müller, Corsin A; Huber, Ludwig

2017-07-01

Emotional contagion, a basic component of empathy defined as emotional state-matching between individuals, has previously been shown in dogs even upon solely hearing negative emotional sounds of humans or conspecifics. The current investigation further sheds light on this phenomenon by directly contrasting emotional sounds of both species (humans and dogs) as well as opposed valences (positive and negative) to gain insights into intra- and interspecies empathy as well as differences between positively and negatively valenced sounds. Different types of sounds were played back to measure the influence of three dimensions on the dogs' behavioural response. We found that dogs behaved differently after hearing non-emotional sounds of their environment compared to emotional sounds of humans and conspecifics ("Emotionality" dimension), but the subjects responded similarly to human and conspecific sounds ("Species" dimension). However, dogs expressed more freezing behaviour after conspecific sounds, independent of the valence. Comparing positively with negatively valenced sounds of both species ("Valence" dimension), we found that, independent of the species from which the sound originated, dogs expressed more behavioural indicators for arousal and negatively valenced states after hearing negative emotional sounds. This response pattern indicates emotional state-matching or emotional contagion for negative sounds of humans and conspecifics. It furthermore indicates that dogs recognized the different valences of the emotional sounds, which is a promising finding for future studies on empathy for positive emotional states in dogs.

Perception Evolution Network Based on Cognition Deepening Model--Adapting to the Emergence of New Sensory Receptor.

PubMed

Xing, Youlu; Shen, Furao; Zhao, Jinxi

2016-03-01

The proposed perception evolution network (PEN) is a biologically inspired neural network model for unsupervised learning and online incremental learning. It is able to automatically learn suitable prototypes from learning data in an incremental way, and it does not require the predefined prototype number or the predefined similarity threshold. Meanwhile, being more advanced than the existing unsupervised neural network model, PEN permits the emergence of a new dimension of perception in the perception field of the network. When a new dimension of perception is introduced, PEN is able to integrate the new dimensional sensory inputs with the learned prototypes, i.e., the prototypes are mapped to a high-dimensional space, which consists of both the original dimension and the new dimension of the sensory inputs. In the experiment, artificial data and real-world data are used to test the proposed PEN, and the results show that PEN can work effectively.

Conformal mapping in optical biosensor applications.

PubMed

Zumbrum, Matthew E; Edwards, David A

2015-09-01

Optical biosensors are devices used to investigate surface-volume reaction kinetics. Current mathematical models for reaction dynamics rely on the assumption of unidirectional flow within these devices. However, new devices, such as the Flexchip, include a geometry that introduces two-dimensional flow, complicating the depletion of the volume reactant. To account for this, a previous mathematical model is extended to include two-dimensional flow, and the Schwarz-Christoffel mapping is used to relate the physical device geometry to that for a device with unidirectional flow. Mappings for several Flexchip dimensions are considered, and the ligand depletion effect is investigated for one of these mappings. Estimated rate constants are produced for simulated data to quantify the inclusion of two-dimensional flow in the mathematical model.

A Sensory 3D Map of the Odor Description Space Derived from a Comparison of Numeric Odor Profile Databases.

PubMed

Zarzo, Manuel

2015-06-01

Many authors have proposed different schemes of odor classification, which are useful to aid the complex task of describing smells. However, reaching a consensus on a particular classification seems difficult because our psychophysical space of odor description is a continuum and is not clustered into well-defined categories. An alternative approach is to describe the perceptual space of odors as a low-dimensional coordinate system. This idea was first proposed by Crocker and Henderson in 1927, who suggested using numeric profiles based on 4 dimensions: "fragrant," "acid," "burnt," and "caprylic." In the present work, the odor profiles of 144 aroma chemicals were compared by means of statistical regression with comparable numeric odor profiles obtained from 2 databases, enabling a plausible interpretation of the 4 dimensions. Based on the results and taking into account comparable 2D sensory maps of odor descriptors from the literature, a 3D sensory map (odor cube) has been drawn up to improve understanding of the similarities and dissimilarities of the odor descriptors most frequently used in fragrance chemistry. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Relating precipitation to fronts at a sub-daily basis

NASA Astrophysics Data System (ADS)

Hénin, Riccardo; Ramos, Alexandre M.; Liberato, Margarida L. R.; Gouveia, Célia

2017-04-01

High impact events over Western Iberia include precipitation extremes that are cause for concern as they lead to flooding, landslides, extensive property damage and human casualties. These events are usually associated with low pressure systems over the North Atlantic moving eastward towards the European western coasts (Liberato and Trigo, 2014). A method to detect fronts and to associate amounts of precipitation to each front is tested, distinguishing between warm and cold fronts. The 6-hourly ERA-interim 1979-2012 reanalysis with 1°x1° horizontal resolution is used for the purpose. An objective front identification method (the Thermal Method described in Shemm et al., 2014) is applied to locate fronts all over the Northern Hemisphere considering the equivalent potential temperature as thermal parameter to use in the model. On the other hand, we settled a squared search box of tuneable dimension (from 2 to 10 degrees long) to look for a front in the neighbourhood of a grid point affected by precipitation. A sensitivity analysis is performed and the optimal dimension of the box is assessed in order to avoid over(under) estimation of precipitation. This is performed in the light of the variability and typical dynamics of warm/cold frontal systems in the Western Europe region. Afterwards, using the extreme event ranking over Iberia proposed by Ramos et al. (2014) the first ranked extreme events are selected in order to validate the method with specific case studies. Finally, climatological and trend maps of frontal activity are produced both on annual and seasonal scales. Trend maps show a decrease of frontal precipitation over north-western Europe and a slight increase over south-western Europe, mainly due to warm fronts. REFERENCES Liberato M.L.R. and R.M. Trigo (2014) Extreme precipitation events and related impacts in Western Iberia. Hydrology in a Changing World: Environmental and Human Dimensions. IAHS Red Book No 363, 171-176. ISSN: 0144-7815. Ramos A.M., R.M. Trigo and M.L.R. Liberato (2014) A ranking of high-resolution daily precipitation extreme events for the Iberian Peninsula, Atmospheric Science Letters 15, 328 - 334. doi: 10.1002/asl2.507. Shemm S., I. Rudeva and I. Simmonds (2014) Extratropical fronts in the lower troposphere - global perspectives obtained from two automated methods. Quarterly Journal of the Royal Meteorological Society, 141: 1686-1698, doi: 10.1002/qj.2471. ACKNOWLEDGEMENTS This work is supported by FCT - project UID/GEO/50019/2013 - Instituto Dom Luiz. Fundação para a Ciência e a Tecnologia, Portugal (FCT) is also providing for R. Hénin doctoral grant (PD/BD/114479/2016) and A.M. Ramos postdoctoral grant (FCT/DFRH/SFRH/BPD/84328/2012).

Origin of Everything and the 21 Dimensions of the Universe

NASA Astrophysics Data System (ADS)

Loev, Mark

2009-03-01

The Dimensions of the Universe correspond with the Dimensions of the human body. The emotion that is a positive for every dimension is Love. The negative emotion that effects each dimension are listed. All seven negative emotions effect Peace, Love and Happiness. 21st Dimension: Happiness Groin & Heart 20th Dimension: Love Groin & Heart 19th Dimension: Peace Groin & heart 18th Dimension: Imagination Wave Eyes Anger 17th Dimension: Z Wave / Closed Birth 16th Dimension: Electromagnetic Wave Ears Anger 15th Dimension: Universal Wave Skin Worry 14th Dimension: Lover Wave Blood Hate 13th Dimension: Disposal Wave Buttocks Fear 12th Dimension: Builder Wave Hands Hate 11th Dimension: Energy Wave Arms Fear 10th Dimension: Time Wave Brain Pessimism 9th Dimension: Gravity Wave Legs Fear 8th Dimension: Sweet Wave Pancreas Fear 7th Dimension: File Wave Left Lung Fear 6th Dimension: Breathing Wave Right Lung Fear 5th Dimension: Digestive Wave Stomach Fear 4th Dimension: Swab Wave Liver Guilt 3rd Dimension: Space Wave Face Sadness 2nd Dimension: Line Wave Mouth Revenge 1st Dimension: Dot Wave Nose Sadness The seven deadly sins correspond: Anger Hate Sadness Fear Worry Pessimism Revenge Note: Guilt is fear

Chaos and Fractals in C-K Map

NASA Astrophysics Data System (ADS)

Wang, Xing-Yuan; Liang, Qing-Yong; Meng, Juan

The characteristic of the fixed points of the Carotid-Kundalini (C-K) map is investigated and the boundary equation of the first bifurcation of the C-K map in the parameter plane is given. Based on the studies of the phase graph, the power spectrum, the correlation dimension and the Lyapunov exponents, the paper reveals the general features of the C-K map transforming from regularity. Meanwhile, using the periodic scanning technology proposed by Welstead and Cromer, a series of Mandelbrot-Julia (M-J) sets of the complex C-K map are constructed. The symmetry of M-J set and the topological inflexibility of distributing of periodic region in the Mandelbrot set are investigated. By founding the whole portray of Julia sets based on Mandelbrot set qualitatively, we find out that Mandelbrot sets contain abundant information of structure of Julia sets.

Fear-Conditioning Mechanisms Associated with Trait Vulnerability to Anxiety in Humans

PubMed Central

Indovina, Iole; Robbins, Trevor W.; Núñez-Elizalde, Anwar O.; Dunn, Barnaby D.; Bishop, Sonia J.

2011-01-01

Summary Investigations of fear conditioning in rodents and humans have illuminated the neural mechanisms underlying cued and contextual fear. A critical question is how personality dimensions such as trait anxiety act through these mechanisms to confer vulnerability to anxiety disorders, and whether humans' ability to overcome acquired fears depends on regulatory skills not characterized in animal models. In a neuroimaging study of fear conditioning in humans, we found evidence for two independent dimensions of neurocognitive function associated with trait vulnerability to anxiety. The first entailed increased amygdala responsivity to phasic fear cues. The second involved impoverished ventral prefrontal cortical (vPFC) recruitment to downregulate both cued and contextual fear prior to omission (extinction) of the aversive unconditioned stimulus. These two dimensions may contribute to symptomatology differences across anxiety disorders; the amygdala mechanism affecting the development of phobic fear and the frontal mechanism influencing the maintenance of both specific fears and generalized anxiety. PMID:21315265

Conception of a method for the creation of volcanic risk index maps

NASA Astrophysics Data System (ADS)

Bion, P.; Van Wyk de Vries, B.; Valentine, G.

2012-04-01

Risk index maps are a variant of risk maps, having the advantage of containing unique kinds of information - levels of risk spatially represented - and can therefore be a more effective communication tool than traditional risk maps. Nevertheless, despite their apparent simplicity, their achievement is the result of a complex risk analysis, requiring the consideration of multidisciplinary indicators, expressing different parameters of the physical and human dimensions of the environment and their interactions. The risk index is obtained in three main stages: the definition of hazard and vulnerability indicators, the transformation of the indicators into subindices through mathematical processes (formulation, standardization, weighting), and the combination of the subindices into a final index. As of now, only few attempts of risk quantification have been done, related to landslide, flood or seismic hazards, and those linked to volcanic hazards are very incomplete because of the specificities and complexities of these kinds of events and their effects. Volcanic hazards have the particularity of being of different types, moreover all events can combine together or be combined with other external events (e.g. meteorological), and they can reach and therefore affect extensive areas by different phenomena. The methodology developed here assesses risk levels in regions potentially impacted by volcanic hazards. It incorporates volcanic hazard specificities and nuances of "vulnerability" by integrating the diversity of the environmental components. It analyses the natural and human strengths, weaknesses, opportunities and threats, which are located within the areas potentially "at risk". Consequently, it considers negative but also positive indicators (respectively aggravating and improving the potential consequences), which can be internal but also external to the volcanic hazards. The approach also considers a temporal variability of the events and their direct or indirect associated effects. The developed approach tends to be especially aimed at urban planners, who would possess a new fundamental tool for organizing the territories located "nearby" volcanoes, in which population density is continually increasing. The volcanic risk index maps would give indications on the areas with the highest risk level, and the urban planners would also be able to determine the elements causing such level. This would lead them to the possibility of proposing recommendations and adequate measures to participate to the reduction of vulnerability, in particular in limiting the exposure and the impacts associated with the volcanic hazards, which would consequently reduce the volcanic risks.

Extensive Tonotopic Mapping across Auditory Cortex Is Recapitulated by Spectrally Directed Attention and Systematically Related to Cortical Myeloarchitecture

PubMed Central

2017-01-01

Auditory selective attention is vital in natural soundscapes. But it is unclear how attentional focus on the primary dimension of auditory representation—acoustic frequency—might modulate basic auditory functional topography during active listening. In contrast to visual selective attention, which is supported by motor-mediated optimization of input across saccades and pupil dilation, the primate auditory system has fewer means of differentially sampling the world. This makes spectrally-directed endogenous attention a particularly crucial aspect of auditory attention. Using a novel functional paradigm combined with quantitative MRI, we establish in male and female listeners that human frequency-band-selective attention drives activation in both myeloarchitectonically estimated auditory core, and across the majority of tonotopically mapped nonprimary auditory cortex. The attentionally driven best-frequency maps show strong concordance with sensory-driven maps in the same subjects across much of the temporal plane, with poor concordance in areas outside traditional auditory cortex. There is significantly greater activation across most of auditory cortex when best frequency is attended, versus ignored; the same regions do not show this enhancement when attending to the least-preferred frequency band. Finally, the results demonstrate that there is spatial correspondence between the degree of myelination and the strength of the tonotopic signal across a number of regions in auditory cortex. Strong frequency preferences across tonotopically mapped auditory cortex spatially correlate with R1-estimated myeloarchitecture, indicating shared functional and anatomical organization that may underlie intrinsic auditory regionalization. SIGNIFICANCE STATEMENT Perception is an active process, especially sensitive to attentional state. Listeners direct auditory attention to track a violin's melody within an ensemble performance, or to follow a voice in a crowded cafe. Although diverse pathologies reduce quality of life by impacting such spectrally directed auditory attention, its neurobiological bases are unclear. We demonstrate that human primary and nonprimary auditory cortical activation is modulated by spectrally directed attention in a manner that recapitulates its tonotopic sensory organization. Further, the graded activation profiles evoked by single-frequency bands are correlated with attentionally driven activation when these bands are presented in complex soundscapes. Finally, we observe a strong concordance in the degree of cortical myelination and the strength of tonotopic activation across several auditory cortical regions. PMID:29109238

Extensive Tonotopic Mapping across Auditory Cortex Is Recapitulated by Spectrally Directed Attention and Systematically Related to Cortical Myeloarchitecture.

PubMed

Dick, Frederic K; Lehet, Matt I; Callaghan, Martina F; Keller, Tim A; Sereno, Martin I; Holt, Lori L

2017-12-13

Auditory selective attention is vital in natural soundscapes. But it is unclear how attentional focus on the primary dimension of auditory representation-acoustic frequency-might modulate basic auditory functional topography during active listening. In contrast to visual selective attention, which is supported by motor-mediated optimization of input across saccades and pupil dilation, the primate auditory system has fewer means of differentially sampling the world. This makes spectrally-directed endogenous attention a particularly crucial aspect of auditory attention. Using a novel functional paradigm combined with quantitative MRI, we establish in male and female listeners that human frequency-band-selective attention drives activation in both myeloarchitectonically estimated auditory core, and across the majority of tonotopically mapped nonprimary auditory cortex. The attentionally driven best-frequency maps show strong concordance with sensory-driven maps in the same subjects across much of the temporal plane, with poor concordance in areas outside traditional auditory cortex. There is significantly greater activation across most of auditory cortex when best frequency is attended, versus ignored; the same regions do not show this enhancement when attending to the least-preferred frequency band. Finally, the results demonstrate that there is spatial correspondence between the degree of myelination and the strength of the tonotopic signal across a number of regions in auditory cortex. Strong frequency preferences across tonotopically mapped auditory cortex spatially correlate with R 1 -estimated myeloarchitecture, indicating shared functional and anatomical organization that may underlie intrinsic auditory regionalization. SIGNIFICANCE STATEMENT Perception is an active process, especially sensitive to attentional state. Listeners direct auditory attention to track a violin's melody within an ensemble performance, or to follow a voice in a crowded cafe. Although diverse pathologies reduce quality of life by impacting such spectrally directed auditory attention, its neurobiological bases are unclear. We demonstrate that human primary and nonprimary auditory cortical activation is modulated by spectrally directed attention in a manner that recapitulates its tonotopic sensory organization. Further, the graded activation profiles evoked by single-frequency bands are correlated with attentionally driven activation when these bands are presented in complex soundscapes. Finally, we observe a strong concordance in the degree of cortical myelination and the strength of tonotopic activation across several auditory cortical regions. Copyright © 2017 Dick et al.

Digital quantum simulation of Dirac equation with a trapped ion

NASA Astrophysics Data System (ADS)

Shen, Yangchao; Zhang, Xiang; Zhang, Junhua; Casanova, Jorge; Lamata, Lucas; Solano, Enrique; Yung, Man-Hong; Zhang, Jingning; Kim, Kihwan; Department Of Physical Chemistry Collaboration

2014-05-01

Recently there has been growing interest in simulating relativistic effects in controllable physical system. We digitally simulate the Dirac equation in 3 +1 dimensions with a single trapped ion. We map four internal levels of 171Yb+ ion to the Dirac bispinor. The time evolution of the Dirac equation is implemented by trotter expansion. In the 3 +1 dimension, we can observe a helicoidal motion of a free Dirac particle which reduces to Zitterbewegung in 1 +1 dimension. This work was supported in part by the National Basic Research Program of China Grant 2011CBA00300, 2011CBA00301, the National Natural Science Foundation of China Grant 61033001, 61061130540. KK acknowledge the support from the recruitment program of global youth experts.

Clinical concept mapping: Does it improve discipline-based critical thinking of nursing students?

PubMed

Moattari, Marzieh; Soleimani, Sara; Moghaddam, Neda Jamali; Mehbodi, Farkhondeh

2014-01-01

Enhancing nursing students' critical thinking is a challenge faced by nurse educators. This study aimed at determining the effect of clinical concept mapping on discipline-based critical thinking of nursing students. In this quasi-experimental post-test only design, a convenient sample of 4(th) year nursing students (N = 32) participated. They were randomly divided into two groups. The experimental group participated in a 1-day workshop on clinical concept mapping. They were also assigned to use at least two clinical concepts mapping during their clinical practice. Post-test was done using a specially designed package consisting of vignettes for measurement of 17 dimensions of critical thinking in nursing under two categories of cognitive critical thinking skills and habits of mind. They were required to write about how they would use a designated critical thinking skills or habits of mind to accomplish the nursing actions. The students' responses were evaluated based on identification of critical thinking, justification, and quality of the student's response. The mean score of both groups was compared by Mann-Whitney test using SPSS version 16.5. The results of the study revealed a significant difference between the two groups' critical thinking regarding identification, justification, and quality of responses, and overall critical thinking scores, cognitive thinking skills, and habits of mind. The two groups also differed significantly from each other in 11 out of 17 dimensions of critical thinking. Clinical concept mapping is a valuable strategy for improvement of critical thinking of nursing students. However, further studies are recommended to generalize this result to nursing students in their earlier stage of education.

Correlation of spatial climate/weather maps and the advantages of using the Mahalanobis metric in predictions

NASA Astrophysics Data System (ADS)

Stephenson, D. B.

1997-10-01

The skill in predicting spatially varying weather/climate maps depends on the definition of the measure of similarity between the maps. Under the justifiable approximation that the anomaly maps are distributed multinormally, it is shown analytically that the choice of weighting metric, used in defining the anomaly correlation between spatial maps, can change the resulting probability distribution of the correlation coefficient. The estimate of the numbers of degrees of freedom based on the variance of the correlation distribution can vary from unity up to the number of grid points depending on the choice of weighting metric. The (pseudo-) inverse of the sample covariance matrix acts as a special choice for the metric in that it gives a correlation distribution which has minimal kurtosis and maximum dimension. Minimal kurtosis suggests that the average predictive skill might be improved due to the rarer occurrence of troublesome outlier patterns far from the mean state. Maximum dimension has a disadvantage for analogue prediction schemes in that it gives the minimum number of analogue states. This metric also has an advantage in that it allows one to powerfully test the null hypothesis of multinormality by examining the second and third moments of the correlation coefficient which were introduced by Mardia as invariant measures of multivariate kurtosis and skewness. For these reasons, it is suggested that this metric could be usefully employed in the prediction of weather/climate and in fingerprinting anthropogenic climate change. The ideas are illustrated using the bivariate example of the observed monthly mean sea-level pressures at Darwin and Tahitifrom 1866 1995.

Globally optimal superconducting magnets part I: minimum stored energy (MSE) current density map.

PubMed

Tieng, Quang M; Vegh, Viktor; Brereton, Ian M

2009-01-01

An optimal current density map is crucial in magnet design to provide the initial values within search spaces in an optimization process for determining the final coil arrangement of the magnet. A strategy for obtaining globally optimal current density maps for the purpose of designing magnets with coaxial cylindrical coils in which the stored energy is minimized within a constrained domain is outlined. The current density maps obtained utilising the proposed method suggests that peak current densities occur around the perimeter of the magnet domain, where the adjacent peaks have alternating current directions for the most compact designs. As the dimensions of the domain are increased, the current density maps yield traditional magnet designs of positive current alone. These unique current density maps are obtained by minimizing the stored magnetic energy cost function and therefore suggest magnet coil designs of minimal system energy. Current density maps are provided for a number of different domain arrangements to illustrate the flexibility of the method and the quality of the achievable designs.

Maximally Informative Statistics for Localization and Mapping

NASA Technical Reports Server (NTRS)

Deans, Matthew C.

2001-01-01

This paper presents an algorithm for localization and mapping for a mobile robot using monocular vision and odometry as its means of sensing. The approach uses the Variable State Dimension filtering (VSDF) framework to combine aspects of Extended Kalman filtering and nonlinear batch optimization. This paper describes two primary improvements to the VSDF. The first is to use an interpolation scheme based on Gaussian quadrature to linearize measurements rather than relying on analytic Jacobians. The second is to replace the inverse covariance matrix in the VSDF with its Cholesky factor to improve the computational complexity. Results of applying the filter to the problem of localization and mapping with omnidirectional vision are presented.

A radiation hybrid map of the distal short arm of human chromosome II, containing the Beckwith-Weidemann and associated embroyonal tumor disease loci

DOE Office of Scientific and Technical Information (OSTI.GOV)

Richard, C.W. III; Berg, D.J.; Meeker, T.C.

1993-05-01

The authors describe a high-resolution radiation hybrid (RH) map of the distal short arm of human chromosome 11 containing the Beckwith-Weidemann gene and the associated embryonal tumor disease loci. Thirteen human 11p15 genes and 17 new anonymous probes were mapped by a statistical analysis of the cosegregation of markers in 102 rodent-human radiation hybrids retaining fragments of human chromosome 11. The 17 anonymous probes were generated from lambda phage containing human 11p15.5 inserts, by using ALU-PCR. A comprehensive map of all 30 loci and a framework map of nine clusters of loci ordered at odds of 1,000:1 were constructed bymore » a multipoint maximum-likelihood approach by using the computer program RHMAP. This RH map localizes one new gene to chromosome 11p15 (WEE1), provides more precise order information for several 11p15 genes (CTSD, H19, HPX,.ST5, RNH, and SMPD1), confirms previous map orders for other 11p15 genes (CALCA, PTH, HBBC, TH, HRAS, and DRD4), and maps 17 new anonymous probes within the 11p15.5 region. This RH map should prove useful in better defining the positions of the Beckwith-Weidemann and associated embryonal tumor disease-gene loci. 41 refs., 1 fig., 2 tabs.« less

Proceedings of the second conference on the human dimensions of wildland fire

Treesearch

Sarah M. McCaffrey; Cherie LeBlanc, eds. Fisher

2011-01-01

This proceedings contains articles, posters, and abstracts of presentations from the second Human Dimensions of Wildland Fire Conference held 27-29 April 2010 in San Antonio, Texas. The conference covered the social issues at the root of wildland fire management’s most serious challenges. Specific topics included: firefighter and public safety; social acceptance of...

Family and Consumer Sciences Focus on the Human Dimension: The Expanded Food and Nutrition Education Program Example

ERIC Educational Resources Information Center

Cason, Katherine L.; Chipman, Helen; Forstadt, Leslie A.; Rasco, Mattie R.; Sellers, Debra M.; Stephenson, Laura; York, De'Shoin A.

2017-01-01

The history of family and consumer sciences (FCS) and the Expanded Food and Nutrition Education Program (EFNEP) is discussed with an emphasis on the critical importance of the human dimension. EFNEP's focus on people, education for change, accountability, strategic partnerships, and public value are highlighted as an example and model for…

Natural and human dimensions of a quasi-wild species:the case of kudzu

Treesearch

Zhenyu Li; Quan Dong; Thomas Albright; Qinfeng Guo

2011-01-01

The human dimensions of biotic invasion are generally poorly understood, even among the most familiar invasive species. Kudzu (Pueraria montana (Lour.) Merr.) is a prominent invasive plant and an example of quasi-wild species, which has experienced repeated introduction, cultivation, and escape back to the wild. Here, we review a large body of primary scientific and...

Development of the Human Interaction Dimension of the Self-Regulated Learning Questionnaire in Asynchronous Online Learning Environments

ERIC Educational Resources Information Center

Cho, Moon-Heum; Jonassen, David

2009-01-01

Two studies focusing on the development and validation of the Online Self-Regulated Learning Inventory (OSRLI) were conducted. The OSRLI is a self-report instrument assessing the human interaction dimension of online self-regulated learning. It consists of an affect/motivation scale and an interaction strategies scale. In Study 1, exploratory…

Insights on correlation dimension from dynamics mapping of three experimental nonlinear laser systems.

PubMed

McMahon, Christopher J; Toomey, Joshua P; Kane, Deb M

2017-01-01

We have analysed large data sets consisting of tens of thousands of time series from three Type B laser systems: a semiconductor laser in a photonic integrated chip, a semiconductor laser subject to optical feedback from a long free-space-external-cavity, and a solid-state laser subject to optical injection from a master laser. The lasers can deliver either constant, periodic, pulsed, or chaotic outputs when parameters such as the injection current and the level of external perturbation are varied. The systems represent examples of experimental nonlinear systems more generally and cover a broad range of complexity including systematically varying complexity in some regions. In this work we have introduced a new procedure for semi-automatically interrogating experimental laser system output power time series to calculate the correlation dimension (CD) using the commonly adopted Grassberger-Proccacia algorithm. The new CD procedure is called the 'minimum gradient detection algorithm'. A value of minimum gradient is returned for all time series in a data set. In some cases this can be identified as a CD, with uncertainty. Applying the new 'minimum gradient detection algorithm' CD procedure, we obtained robust measurements of the correlation dimension for many of the time series measured from each laser system. By mapping the results across an extended parameter space for operation of each laser system, we were able to confidently identify regions of low CD (CD < 3) and assign these robust values for the correlation dimension. However, in all three laser systems, we were not able to measure the correlation dimension at all parts of the parameter space. Nevertheless, by mapping the staged progress of the algorithm, we were able to broadly classify the dynamical output of the lasers at all parts of their respective parameter spaces. For two of the laser systems this included displaying regions of high-complexity chaos and dynamic noise. These high-complexity regions are differentiated from regions where the time series are dominated by technical noise. This is the first time such differentiation has been achieved using a CD analysis approach. More can be known of the CD for a system when it is interrogated in a mapping context, than from calculations using isolated time series. This has been shown for three laser systems and the approach is expected to be useful in other areas of nonlinear science where large data sets are available and need to be semi-automatically analysed to provide real dimensional information about the complex dynamics. The CD/minimum gradient algorithm measure provides additional information that complements other measures of complexity and relative complexity, such as the permutation entropy; and conventional physical measurements.

Insights on correlation dimension from dynamics mapping of three experimental nonlinear laser systems

PubMed Central

McMahon, Christopher J.; Toomey, Joshua P.

2017-01-01

Background We have analysed large data sets consisting of tens of thousands of time series from three Type B laser systems: a semiconductor laser in a photonic integrated chip, a semiconductor laser subject to optical feedback from a long free-space-external-cavity, and a solid-state laser subject to optical injection from a master laser. The lasers can deliver either constant, periodic, pulsed, or chaotic outputs when parameters such as the injection current and the level of external perturbation are varied. The systems represent examples of experimental nonlinear systems more generally and cover a broad range of complexity including systematically varying complexity in some regions. Methods In this work we have introduced a new procedure for semi-automatically interrogating experimental laser system output power time series to calculate the correlation dimension (CD) using the commonly adopted Grassberger-Proccacia algorithm. The new CD procedure is called the ‘minimum gradient detection algorithm’. A value of minimum gradient is returned for all time series in a data set. In some cases this can be identified as a CD, with uncertainty. Findings Applying the new ‘minimum gradient detection algorithm’ CD procedure, we obtained robust measurements of the correlation dimension for many of the time series measured from each laser system. By mapping the results across an extended parameter space for operation of each laser system, we were able to confidently identify regions of low CD (CD < 3) and assign these robust values for the correlation dimension. However, in all three laser systems, we were not able to measure the correlation dimension at all parts of the parameter space. Nevertheless, by mapping the staged progress of the algorithm, we were able to broadly classify the dynamical output of the lasers at all parts of their respective parameter spaces. For two of the laser systems this included displaying regions of high-complexity chaos and dynamic noise. These high-complexity regions are differentiated from regions where the time series are dominated by technical noise. This is the first time such differentiation has been achieved using a CD analysis approach. Conclusions More can be known of the CD for a system when it is interrogated in a mapping context, than from calculations using isolated time series. This has been shown for three laser systems and the approach is expected to be useful in other areas of nonlinear science where large data sets are available and need to be semi-automatically analysed to provide real dimensional information about the complex dynamics. The CD/minimum gradient algorithm measure provides additional information that complements other measures of complexity and relative complexity, such as the permutation entropy; and conventional physical measurements. PMID:28837602

Using digital photogrammetry to constrain the segmentation of Paleocene volcanic marker horizons within the Nuussuaq basin

NASA Astrophysics Data System (ADS)

Vest Sørensen, Erik; Pedersen, Asger Ken

2017-04-01

Digital photogrammetry is used to map important volcanic marker horizons within the Nuussuaq Basin, West Greenland. We use a combination of oblique stereo images acquired from helicopter using handheld cameras and traditional aerial photographs. The oblique imagery consists of scanned stereo photographs acquired with analogue cameras in the 90´ties and newer digital images acquired with high resolution digital consumer cameras. Photogrammetric software packages SOCET SET and 3D Stereo Blend are used for controlling the seamless movement between stereo-models at different scales and viewing angles and the mapping is done stereoscopically using 3d monitors and the human stereopsis. The approach allows us to map in three dimensions three characteristic marker horizons (Tunoqqu, Kûgánguaq and Qordlortorssuaq Members) within the picritic Vaigat Formation. They formed toward the end of the same volcanic episode and are believed to be closely related in time. They formed an approximately coherent sub-horizontal surface, the Tunoqqu Surface that at the time of formation covered more than 3100 km2 on Disko and Nuussuaq. Our mapping shows that the Tunoqqu Surface is now segmented into areas of different elevation and structural trend as a result of later tectonic deformation. This is most notable on Nuussuaq where the western part is elevated and in parts highly faulted. In western Nuussuaq the surface has been uplifted and faulted so that it now forms an asymmetric anticline. The flanks of the anticline are coincident with two N-S oriented pre-Tunoqqu extensional faults. The deformation of the Tunoqqu surface could be explained by inversion of older extensional faults due to an overall E-W directed compressive regime in the late Paleocene.

Indulging anxiety: human enhancement from a Protestant perspective.

PubMed

Hanson, Mark J

1999-08-01

At the heart of any ethics of human enhancement must be some normative assumptions about human nature. The purpose of this essay is to draw on themes from a Protestant theological anthropology to provide a basis for understanding and evaluating the tension between maintaining our humanity and enhancing it. Drawing primarily on the work of theologian Reinhold Niebuhr, I interpret enhancement as proceeding from the anxiety that characterizes human experience at the juncture of freedom and finiteness. Religious and moral dimensions of human sinfulness are considered in relation to cultural values that motivate human enhancement generally. I employ these dimensions in a series of benchmarks to suggest a background of theological, anthropological, and moral considerations against which enhancement is not to be condemmed but rather critically evaluated.

Understanding National Models for Climate Assessments

NASA Astrophysics Data System (ADS)

Dave, A.; Weingartner, K.

2017-12-01

National-level climate assessments have been produced or are underway in a number of countries. These efforts showcase a variety of approaches to mapping climate impacts onto human and natural systems, and involve a variety of development processes, organizational structures, and intended purposes. This presentation will provide a comparative overview of national `models' for climate assessments worldwide, drawing from a geographically diverse group of nations with varying capacities to conduct such assessments. Using an illustrative sampling of assessment models, the presentation will highlight the range of assessment mandates and requirements that drive this work, methodologies employed, focal areas, and the degree to which international dimensions are included for each nation's assessment. This not only allows the U.S. National Climate Assessment to be better understood within an international context, but provides the user with an entry point into other national climate assessments around the world, enabling a better understanding of the risks and vulnerabilities societies face.

Retrieval of Haze Properties in Pluto's Atmosphere from New Horizons Observations

NASA Astrophysics Data System (ADS)

Fan, S.; Gao, P.; Yung, Y. L.

2017-12-01

On July 14th, 2015, New Horizons performed its historic close approach of Pluto, giving humanity unprecedented observations of the dwarf planet's atmosphere. One of the amazing features seen was the multi-layered haze in its atmosphere. The haze was detected both at visible wavelengths by the Long Range Reconnaissance Imager (LORRI) from direct imaging and in the ultraviolet by the Alice spectrograph from solar occultations. Preliminary analysis using simplified models showed that neither spherical nor 2-dimensional aggregate particles could satisfy both sets of observations. In this work, we present a joint retrieval of haze particles using both LORRI and Alice data, which examines various size distributions and dimensions of aggregate particles. We map out the haze particles' phase function by the forward scattering and extinction properties by the occultation. With the combination of these two approaches, the Haze's properties of size and shape are constrained.

Spheres: from Ground Development to ISS Operations

NASA Technical Reports Server (NTRS)

Katterhagen, A.

2016-01-01

SPHERES (Synchronized Position Hold Engage and Reorient Experimental Satellites) is an internal International Space Station (ISS) Facility that supports multiple investigations for the development of multi-spacecraft and robotic control algorithms. The SPHERES National Lab Facility aboard ISS is managed and operated by NASA Ames Research Center (ARC) at Moffett Field California. The SPHERES Facility on ISS consists of three self-contained eight-inch diameter free-floating satellites which perform the various flight algorithms and serve as a platform to support the integration of experimental hardware. SPHERES has served to mature the adaptability of control algorithms of future formation flight missions in microgravity (6 DOF (Degrees of Freedom) / long duration microgravity), demonstrate key close-proximity formation flight and rendezvous and docking maneuvers, understand fault diagnosis and recovery, improve the field of human telerobotic operation and control, and lessons learned on ISS have significant impact on ground robotics, mapping, localization, and sensing in three-dimensions - among several other areas of study.

Mapping visual cortex in monkeys and humans using surface-based atlases

NASA Technical Reports Server (NTRS)

Van Essen, D. C.; Lewis, J. W.; Drury, H. A.; Hadjikhani, N.; Tootell, R. B.; Bakircioglu, M.; Miller, M. I.

2001-01-01

We have used surface-based atlases of the cerebral cortex to analyze the functional organization of visual cortex in humans and macaque monkeys. The macaque atlas contains multiple partitioning schemes for visual cortex, including a probabilistic atlas of visual areas derived from a recent architectonic study, plus summary schemes that reflect a combination of physiological and anatomical evidence. The human atlas includes a probabilistic map of eight topographically organized visual areas recently mapped using functional MRI. To facilitate comparisons between species, we used surface-based warping to bring functional and geographic landmarks on the macaque map into register with corresponding landmarks on the human map. The results suggest that extrastriate visual cortex outside the known topographically organized areas is dramatically expanded in human compared to macaque cortex, particularly in the parietal lobe.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhu, Yuanyuan; Munro, Catherine J.; Olszta, Matthew J.

In this work, we showcase that through precise control of the electron dose rate, state-of-the-art large solid angle energy dispersive X-ray spectroscopy (EDS) mapping in aberration-corrected scanning transmission electron microscope (STEM) is capable of faithful and unambiguous chemical characterization of the Pt and Pd distribution in a peptide-mediated nanosystem. This low-dose-rate recording scheme adds another dimension of flexibility to the design of elemental mapping experiments, and holds significant potential for extending its application to a wide variety of beam sensitive hybrid nanostructures.

Image Processing

NASA Technical Reports Server (NTRS)

1987-01-01

A new spinoff product was derived from Geospectra Corporation's expertise in processing LANDSAT data in a software package. Called ATOM (for Automatic Topographic Mapping), it's capable of digitally extracting elevation information from stereo photos taken by spaceborne cameras. ATOM offers a new dimension of realism in applications involving terrain simulations, producing extremely precise maps of an area's elevations at a lower cost than traditional methods. ATOM has a number of applications involving defense training simulations and offers utility in architecture, urban planning, forestry, petroleum and mineral exploration.

Converting Topographic Maps into Digital Form to Aid in Archeological Research in the Peten, Guatemala

NASA Technical Reports Server (NTRS)

Aldrich, Serena R.

1999-01-01

The purpose of my project was to convert a topographical map into digital form so that the data can be manipulated and easily accessed in the field. With the data in this particular format, Dr. Sever and his colleagues can highlight the specific features of the landscape that they require for their research of the ancient Mayan civilization. Digital elevation models (DEMs) can also be created from the digitized contour features adding another dimension to their research.

Optimal design method to minimize users' thinking mapping load in human-machine interactions.

PubMed

Huang, Yanqun; Li, Xu; Zhang, Jie

2015-01-01

The discrepancy between human cognition and machine requirements/behaviors usually results in serious mental thinking mapping loads or even disasters in product operating. It is important to help people avoid human-machine interaction confusions and difficulties in today's mental work mastered society. Improving the usability of a product and minimizing user's thinking mapping and interpreting load in human-machine interactions. An optimal human-machine interface design method is introduced, which is based on the purpose of minimizing the mental load in thinking mapping process between users' intentions and affordance of product interface states. By analyzing the users' thinking mapping problem, an operating action model is constructed. According to human natural instincts and acquired knowledge, an expected ideal design with minimized thinking loads is uniquely determined at first. Then, creative alternatives, in terms of the way human obtains operational information, are provided as digital interface states datasets. In the last, using the cluster analysis method, an optimum solution is picked out from alternatives, by calculating the distances between two datasets. Considering multiple factors to minimize users' thinking mapping loads, a solution nearest to the ideal value is found in the human-car interaction design case. The clustering results show its effectiveness in finding an optimum solution to the mental load minimizing problems in human-machine interaction design.

Brain/MINDS: brain-mapping project in Japan

PubMed Central

Okano, Hideyuki; Miyawaki, Atsushi; Kasai, Kiyoto

2015-01-01

There is an emerging interest in brain-mapping projects in countries across the world, including the USA, Europe, Australia and China. In 2014, Japan started a brain-mapping project called Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS). Brain/MINDS aims to map the structure and function of neuronal circuits to ultimately understand the vast complexity of the human brain, and takes advantage of a unique non-human primate animal model, the common marmoset (Callithrix jacchus). In Brain/MINDS, the RIKEN Brain Science Institute acts as a central institute. The objectives of Brain/MINDS can be categorized into the following three major subject areas: (i) structure and functional mapping of a non-human primate brain (the marmoset brain); (ii) development of innovative neurotechnologies for brain mapping; and (iii) human brain mapping; and clinical research. Brain/MINDS researchers are highly motivated to identify the neuronal circuits responsible for the phenotype of neurological and psychiatric disorders, and to understand the development of these devastating disorders through the integration of these three subject areas. PMID:25823872

Mycobacterium avium subsp. paratuberculosis in dairy products, meat, and drinking water.

PubMed

Gill, C O; Saucier, L; Meadus, W J

2011-03-01

Mycobacterium avium subsp. paratuberculosis (Map) is the cause of Johne's disease, a chronic infection of the gut, in ruminant animals that provide milk and/or meat for human consumption. Map also may be involved in Crohn's disease and type 1 diabetes in humans. Although the role of Map in human diseases has not been established, minimizing the exposure of humans to the organism is considered desirable as a precautionary measure. Infected animals can shed Map in feces and milk, and the organism can become disseminated in tissues remote from the gut and its associated lymph nodes. The presence of at least some Map in raw milk and meat and in natural waters is likely, but the numbers of Map in those foods and waters should be reduced through cooking or purification. The available information relating to Map in milk and dairy products, meats, and drinking water is reviewed here for assessment of the risks of exposure to Map from consumption of such foods and water.

Pattern Water Use Efficiency perspective on degradation and recovery of shrublands across Mediterranean to Arid transition zones

NASA Astrophysics Data System (ADS)

Shoshany, Maxim

2017-04-01

Shrublands cover a total of 12.7 million km2 , a considerable part of them along semi-arid to arid transition zones. Varying patterns of shrubs, grasses and barren land along such climatic gradients express the spatial dimension of climate change and human disturbance which attracted limited attention in the eco-geomorphic literature. Questions concerning relationships between rainfall, shrublands biomass and their patterns are fundamental for the understanding of these ecosystems response to the expected changes in water availability due to global warming and the increase in human disturbance to natural ecosystems following World population growth. While processes leading to the formation of patterns had attracted considerable attention, the spatial dimension of Water Use Efficiency (WUE) which is a parameter measuring ecosystems productivity in relation to water availability is severely missing. Relative shrub cover is a primary estimator of the fraction of water utilized for shrubs growth. Edge effects must be considered as well in fragmented ecosystems in general and in hot regions in particular since soil temperature in hot regions which frequently exceed 50oC during summer months decreases photosynthesis and productivity in plants bordering bare soil. This edge effect is decreasing with the increase in shrubs' height. Pattern Water Use Efficiency describes the combined effect of shrub cover, shrub height and shrub patches edge zone proportion on water use efficiency. In my presentation I will first present mapping od PWUEs across Mediterranean to arid transition zones in the Eastern Mediterranean. Then I will present several mathematical models describing PWUE for simulated patterns, searching for the spatial parameterization providing the highest sensitivity to patterns responses to changes in habitat conditions. Such simulations would allow us to discuss several PWUE strategies for shrublands recovery under the current scenarios of climate change and human driven degradation.

Small covers of graph-associahedra and realization of cycles

NASA Astrophysics Data System (ADS)

Gaifullin, A. A.

2016-11-01

An oriented connected closed manifold M^n is called a URC-manifold if for any oriented connected closed manifold N^n of the same dimension there exists a nonzero-degree mapping of a finite-fold covering \\widehat{M}^n of M^n onto N^n. This condition is equivalent to the following: for any n-dimensional integral homology class of any topological space X, a multiple of it can be realized as the image of the fundamental class of a finite-fold covering \\widehat{M}^n of M^n under a continuous mapping f\\colon \\widehat{M}^n\\to X. In 2007 the author gave a constructive proof of Thom's classical result that a multiple of any integral homology class can be realized as an image of the fundamental class of an oriented smooth manifold. This construction yields the existence of URC-manifolds of all dimensions. For an important class of manifolds, the so-called small covers of graph-associahedra corresponding to connected graphs, we prove that either they or their two-fold orientation coverings are URC-manifolds. In particular, we obtain that the two-fold covering of the small cover of the usual Stasheff associahedron is a URC-manifold. In dimensions 4 and higher, this manifold is simpler than all the previously known URC-manifolds. Bibliography: 39 titles.

The mouse-human anatomy ontology mapping project.

PubMed

Hayamizu, Terry F; de Coronado, Sherri; Fragoso, Gilberto; Sioutos, Nicholas; Kadin, James A; Ringwald, Martin

2012-01-01

The overall objective of the Mouse-Human Anatomy Project (MHAP) was to facilitate the mapping and harmonization of anatomical terms used for mouse and human models by Mouse Genome Informatics (MGI) and the National Cancer Institute (NCI). The anatomy resources designated for this study were the Adult Mouse Anatomy (MA) ontology and the set of anatomy concepts contained in the NCI Thesaurus (NCIt). Several methods and software tools were identified and evaluated, then used to conduct an in-depth comparative analysis of the anatomy ontologies. Matches between mouse and human anatomy terms were determined and validated, resulting in a highly curated set of mappings between the two ontologies that has been used by other resources. These mappings will enable linking of data from mouse and human. As the anatomy ontologies have been expanded and refined, the mappings have been updated accordingly. Insights are presented into the overall process of comparing and mapping between ontologies, which may prove useful for further comparative analyses and ontology mapping efforts, especially those involving anatomy ontologies. Finally, issues concerning further development of the ontologies, updates to the mapping files, and possible additional applications and significance were considered. DATABASE URL: http://obofoundry.org/cgi-bin/detail.cgi?id=ma2ncit.

A Concept-Mapping Strategy for Assessing Conceptual Change in a Student-Directed, Research-Based Geoscience Course

NASA Astrophysics Data System (ADS)

Rebich, S.

2003-12-01

The concept mapping technique has been proposed as a method for examining the evolving nature of students' conceptualizations of scientific concepts, and promises insight into a dimension of learning different from the one accessible through more conventional classroom testing techniques. The theory behind concept mapping is based on an assumption that knowledge acquisition is accomplished through "linking" of new information to an existing knowledge framework, and that meaningful (as opposed to arbitrary or verbatim) links allow for deeper understanding and conceptual change. Reflecting this theory, concept maps are constructed as a network of related concepts connected by labeled links that illustrate the relationship between the concepts. Two concepts connected by one such link make up a "proposition", the basic element of the concept map structure. In this paper, we examine the results of a pre- and post-test assessment program for an upper-division undergraduate geography course entitled "Mock Environmental Summit," which was part of a research project on assessment. Concept mapping was identified as a potentially powerful assessment tool for this course, as more conventional tools such as multiple-choice tests did not seem to provide a reliable indication of the learning students were experiencing as a result of the student-directed research, presentations, and discussions that make up a substantial portion of the course. The assessment program began at the beginning of the course with a one-hour training session during which students were introduced to the theory behind concept mapping, provided with instructions and guidance for constructing a concept map using the CMap software developed and maintained by the Institute for Human and Machine Cognition at the University of West Florida, and asked to collaboratively construct a concept map on a topic not related to the one to be assessed. This training session was followed by a 45-minute "pre-test" on the topic of global climate change, for which students were provided with a list of questions to guide their thoughts during the concept map construction. Following the pre-test, students were not exposed to further concept mapping until the end of the course, when they were asked to complete a "post-test" consisting of exactly the same task. In addition to a summary of our results, this paper presents an overview of available digital concept-mapping tools, proposed scoring techniques, and design principles to keep in mind when designing a concept-mapping assessment program. We also discuss our experience with concept map assessment, the insights it provided into the evolution in student understanding of global climate change that resulted from the course, and our ideas about the potential role of concept mapping in an overall assessment program for interdisciplinary and/or student-directed curricula.

Human Dimensions of Strategic Leadership : A Selected Bibliogrpahy

DTIC Science & Technology

2013-09-01

2011. 27pp. (AD-A553-001) http://handle.dtic.mil/100.2/ADA553001 Michelson, Brian M. Character Development of U.S. Army Leaders: A Laissez Faire ...Maxime A. “ Fairness Perceptions and Trust as Mediators on the Relationship between Leadership Style, Unit Commitment, and Turnover Intentions of Canadian...HUMAN DIMENSIONS OF STRATEGIC LEADERSHIP A Selected Bibliography U.S. ARMY WAR COLLEGE LIBRARY September 2013

A World Wide Web Human Dimensions Framework and Database for Wildlife and Forest Planning

Treesearch

Michael A. Tarrant; Alan D. Bright; H. Ken Cordell

1999-01-01

The paper describes a human dimensions framework(HDF) for application in wildlife and forest planning. The HDF is delivered via the world wide web and retrieves data on-line from the Social, Economic, Environmental, Leisure, and Attitudes (SEELA) database. The proposed HDF is guided by ten fundamental HD principles, and is applied to wildlife and forest planning using...

Three-dimensional analysis of magnetometer array data

NASA Technical Reports Server (NTRS)

Richmond, A. D.; Baumjohann, W.

1984-01-01

A technique is developed for mapping magnetic variation fields in three dimensions using data from an array of magnetometers, based on the theory of optimal linear estimation. The technique is applied to data from the Scandinavian Magnetometer Array. Estimates of the spatial power spectra for the internal and external magnetic variations are derived, which in turn provide estimates of the spatial autocorrelation functions of the three magnetic variation components. Statistical errors involved in mapping the external and internal fields are quantified and displayed over the mapping region. Examples of field mapping and of separation into external and internal components are presented. A comparison between the three-dimensional field separation and a two-dimensional separation from a single chain of stations shows that significant differences can arise in the inferred internal component.

Development of the “Highly Sensitive Dog” questionnaire to evaluate the personality dimension “Sensory Processing Sensitivity” in dogs

PubMed Central

Asher, Lucy; Furrer, Sibylle; Lechner, Isabel; Würbel, Hanno; Melotti, Luca

2017-01-01

In humans, the personality dimension ‘sensory processing sensitivity (SPS)’, also referred to as “high sensitivity”, involves deeper processing of sensory information, which can be associated with physiological and behavioral overarousal. However, it has not been studied up to now whether this dimension also exists in other species. SPS can influence how people perceive the environment and how this affects them, thus a similar dimension in animals would be highly relevant with respect to animal welfare. We therefore explored whether SPS translates to dogs, one of the primary model species in personality research. A 32-item questionnaire to assess the “highly sensitive dog score” (HSD-s) was developed based on the “highly sensitive person” (HSP) questionnaire. A large-scale, international online survey was conducted, including the HSD questionnaire, as well as questions on fearfulness, neuroticism, “demographic” (e.g. dog sex, age, weight; age at adoption, etc.) and “human” factors (e.g. owner age, sex, profession, communication style, etc.), and the HSP questionnaire. Data were analyzed using linear mixed effect models with forward stepwise selection to test prediction of HSD-s by the above-mentioned factors, with country of residence and dog breed treated as random effects. A total of 3647 questionnaires were fully completed. HSD-, fearfulness, neuroticism and HSP-scores showed good internal consistencies, and HSD-s only moderately correlated with fearfulness and neuroticism scores, paralleling previous findings in humans. Intra- (N = 447) and inter-rater (N = 120) reliabilities were good. Demographic and human factors, including HSP score, explained only a small amount of the variance of HSD-s. A PCA analysis identified three subtraits of SPS, comparable to human findings. Overall, the measured personality dimension in dogs showed good internal consistency, partial independence from fearfulness and neuroticism, and good intra- and inter-rater reliability, indicating good construct validity of the HSD questionnaire. Human and demographic factors only marginally affected the HSD-s suggesting that, as hypothesized for human SPS, a genetic basis may underlie this dimension within the dog species. PMID:28520773

A proteome-scale map of the human interactome network

PubMed Central

Rolland, Thomas; Taşan, Murat; Charloteaux, Benoit; Pevzner, Samuel J.; Zhong, Quan; Sahni, Nidhi; Yi, Song; Lemmens, Irma; Fontanillo, Celia; Mosca, Roberto; Kamburov, Atanas; Ghiassian, Susan D.; Yang, Xinping; Ghamsari, Lila; Balcha, Dawit; Begg, Bridget E.; Braun, Pascal; Brehme, Marc; Broly, Martin P.; Carvunis, Anne-Ruxandra; Convery-Zupan, Dan; Corominas, Roser; Coulombe-Huntington, Jasmin; Dann, Elizabeth; Dreze, Matija; Dricot, Amélie; Fan, Changyu; Franzosa, Eric; Gebreab, Fana; Gutierrez, Bryan J.; Hardy, Madeleine F.; Jin, Mike; Kang, Shuli; Kiros, Ruth; Lin, Guan Ning; Luck, Katja; MacWilliams, Andrew; Menche, Jörg; Murray, Ryan R.; Palagi, Alexandre; Poulin, Matthew M.; Rambout, Xavier; Rasla, John; Reichert, Patrick; Romero, Viviana; Ruyssinck, Elien; Sahalie, Julie M.; Scholz, Annemarie; Shah, Akash A.; Sharma, Amitabh; Shen, Yun; Spirohn, Kerstin; Tam, Stanley; Tejeda, Alexander O.; Trigg, Shelly A.; Twizere, Jean-Claude; Vega, Kerwin; Walsh, Jennifer; Cusick, Michael E.; Xia, Yu; Barabási, Albert-László; Iakoucheva, Lilia M.; Aloy, Patrick; De Las Rivas, Javier; Tavernier, Jan; Calderwood, Michael A.; Hill, David E.; Hao, Tong; Roth, Frederick P.; Vidal, Marc

2014-01-01

SUMMARY Just as reference genome sequences revolutionized human genetics, reference maps of interactome networks will be critical to fully understand genotype-phenotype relationships. Here, we describe a systematic map of ~14,000 high-quality human binary protein-protein interactions. At equal quality, this map is ~30% larger than what is available from small-scale studies published in the literature in the last few decades. While currently available information is highly biased and only covers a relatively small portion of the proteome, our systematic map appears strikingly more homogeneous, revealing a “broader” human interactome network than currently appreciated. The map also uncovers significant inter-connectivity between known and candidate cancer gene products, providing unbiased evidence for an expanded functional cancer landscape, while demonstrating how high quality interactome models will help “connect the dots” of the genomic revolution. PMID:25416956

Investigation of the Fractal Geometry of Tundra Lake Patterns using Historical Topographic Maps and Satellite Imagery.

NASA Astrophysics Data System (ADS)

Kariyawasam, T.; Essa, A.; Gong, M.; Sudakov, I.

2017-12-01

Greenhouse gas emissions from tundra lakes are a significant positive feedback to the atmosphere in a changing climate as a pronounced growth of the numbers of tundra lake patterns has been observed in the Arctic region. Detailed knowledge of spatial dynamics of lake patterns in a changing arctic tundra landscape and their geometrical properties is therefore potentially valuable, in order to understand and accurately model the sources of greenhouse gas emissions from boreal permafrost. Our goal is to use a collection of historical topographic maps and satellite imagery of tundra lakes to conduct computational image analyses for examining spatial dynamics of Tundra lake patterns. Our approach is based upon analyzing area-perimeter data of thousands of tundra lakes to compute the fractal dimension to study the tundra lake pattern geometry, which have been used to classify pollen grains by textual patterning (Mander, 2016), vegetation in dryland ecosystems (Mander, 2017) and melt pond patterns (Hohenegger, 2012). By analyzing area - perimeter data for over 900 lakes we find that for both historical topographic maps and current satellite imagery, the fractal dimension D is stable at 1.6 for Tundra lakes with area less than about 100km2. For Tundra lake sizes bigger than 100 km2 fractal dimension takes values close to 2 and less than one indicative of structural changes in Tundra lake pattern geometry. Furthermore the current study did not reveal any percolation transition above some critical threshold in Tundra lake evolution. The results of the study will provide scientists with new data on these aspects of tundra lakes to help characterize the geomorphology of spatial patterns in arctic tundra lakes.

Interdisciplinary Graduate Training in Polar Environmental Change: Field-based learning in Greenland

NASA Astrophysics Data System (ADS)

Virginia, R. A.; Holm, K.; Whitecloud, S.; Levy, L.; Kelly, M. A.; Feng, X.; Grenoble, L.

2009-12-01

The objective of the NSF-funded Integrative Graduate Education Research Traineeship (IGERT) program at Dartmouth College is to develop a new cohort of environmental scientists and engineers with an interdisciplinary understanding of polar regions and their importance to global environmental change. The Dartmouth IGERT challenges Ph.D. students to consider the broader dimensions of their research and to collaborate with scientists from other disciplines, educators, and policy makers. IGERT students will focus on research questions that are relevant to the needs of local people experiencing climate change and on understanding the ethical responsibilities and benefits of conducting research in partnership with northern residents and institutions. Seven Ph.D. students from the departments of Earth Sciences, Engineering, and Ecology and Evolutionary Biology at Dartmouth College make up the first IGERT cohort for the five-year program. The Dartmouth IGERT curriculum will focus on three main components of polar systems responding to recent climate change: the cryosphere, terrestrial ecosystems, and biogeochemical cycles. The integrating experience of the core curriculum is the Greenland Field Seminar that will take place in Kangerlussuaq (terrestrial and aquatic systems), Summit Camp (snow and ice) and Nuuk, Greenland (human dimensions of change). In Nuuk, IGERT students will share their science and develop partnerships with students, educators, and policy makers at the University of Greenland, the Inuit Circumpolar Council (ICC), and other Greenlandic institutions. In summer 2009 the authors conducted preliminary fieldwork near Kangerlussuaq, Greenland to develop aspects of the science curriculum for the 2010 Greenland Field Seminar and to explore research topics for IGERT Fellows (Levy and Whitecloud). Examples of results presented here are designed to develop field-based learning activities. These include soil and vegetation relationships as a function of aspect, stable isotope ratios and hydrochemistry of lake waters, mapping of past glacial extents and sampling for berylium-10 surface exposure dating. Two IGERT investigators (Virginia and Grenoble) worked with colleagues in Nuuk (Holm) to develop the human dimensions curriculum including the recent political changes in Greenland, the role of traditional ecological knowledge in resource management and environmental research, and the interrelations between language, climate and subsistence lifestyles.

Functional slit lamp biomicroscopy for imaging bulbar conjunctival microvasculature in contact lens wearers

PubMed Central

Jiang, Hong; Zhong, Jianguang; DeBuc, Delia Cabrera; Tao, Aizhu; Xu, Zhe; Lam, Byron L.; Liu, Che; Wang, Jianhua

2014-01-01

Purpose To develop, test and validate functional slit lamp biomicroscopy (FSLB) for generating non-invasive bulbar conjunctival microvascular perfusion maps (nMPMs) and assessing morphometry and hemodyanmics. Methods FSLB was adapted from a traditional slit-lamp microscope by attaching a digital camera to image the bulbar conjunctiva to create nMPMs and measure venular blood flow hemodyanmics. High definition images with a large field of view were obtained on the temporal bulbar conjunctiva for creating nMPMs. A high imaging rate of 60 frame per second and a ~210× high magnification were achieved using the camera inherited high speed setting and movie crop function, for imaging hemodyanmics. Custom software was developed to segment bulbar conjunctival nMPMs for further fractal analysis and quantitatively measure blood vessel diameter, blood flow velocity and flow rate. Six human subjects were imaged before and after 6 hours of wearing contact lenses. Monofractal and multifractal analyses were performed to quantify fractality of the nMPMs. Results The mean bulbar conjunctival vessel diameter was 18.8 ± 2.7 μm at baseline and increased to 19.6 ± 2.4 μm after 6 hours of lens wear (P = 0.020). The blood flow velocity was increased from 0.60 ± 0.12 mm/s to 0.88 ± 0.21 mm/s (P = 0.001). The blood flow rate was also increased from 129.8 ± 59.9 pl/s to 207.2 ± 81.3 pl/s (P = 0.001). Bulbar conjunctival nMPMs showed the intricate details of the bulbar conjunctival microvascular network. At baseline, fractal dimension was 1.63 ± 0.05 and 1.71 ± 0.03 analyzed by monofractal and multifractal analysis, respectively. Significant increases in fractal dimensions were found after 6 hours of lens wear (P < 0.05). Conclusions Microvascular network’s fractality, morphometry and hemodyanmics of the human bulbar conjunctiva can be measured easily and reliably using FSLB. The alternations of the fractal dimensions, morphometry and hemodyanmics during contact lens wear may indicate ocular microvascular responses to contact lens wear. PMID:24444784

The Representation of Three-Dimensional Space in Fish

PubMed Central

Burt de Perera, Theresa; Holbrook, Robert I.; Davis, Victoria

2016-01-01

In mammals, the so-called “seat of the cognitive map” is located in place cells within the hippocampus. Recent work suggests that the shape of place cell fields might be defined by the animals’ natural movement; in rats the fields appear to be laterally compressed (meaning that the spatial map of the animal is more highly resolved in the horizontal dimensions than in the vertical), whereas the place cell fields of bats are statistically spherical (which should result in a spatial map that is equally resolved in all three dimensions). It follows that navigational error should be equal in the horizontal and vertical dimensions in animals that travel freely through volumes, whereas in surface-bound animals would demonstrate greater vertical error. Here, we describe behavioral experiments on pelagic fish in which we investigated the way that fish encode three-dimensional space and we make inferences about the underlying processing. Our work suggests that fish, like mammals, have a higher order representation of space that assembles incoming sensory information into a neural unit that can be used to determine position and heading in three-dimensions. Further, our results are consistent with this representation being encoded isotropically, as would be expected for animals that move freely through volumes. Definitive evidence for spherical place fields in fish will not only reveal the neural correlates of space to be a deep seated vertebrate trait, but will also help address the questions of the degree to which environment spatial ecology has shaped cognitive processes and their underlying neural mechanisms. PMID:27014002

Natural landscape features, human-related attractants, and conflict hotspots: A spatial analysis of human-grizzly bear conflicts

USGS Publications Warehouse

Wilson, S.M.; Madel, M.J.; Mattson, D.J.; Graham, J.M.; Burchfield, J.A.; Belsky, J.M.

2005-01-01

There is a long history of conflict in the western United States between humans and grizzly bears (Ursus arctos) involving agricultural attractants. However, little is known about the spatial dimensions of this conflict and the relative importance of different attractants. This study was undertaken to better understand the spatial and functional components of conflict between humans and grizzly bears on privately owned agricultural lands in Montana. Our investigations focused on spatial associations of rivers and creeks, livestock pastures, boneyards (livestock carcass dump sites), beehives, and grizzly bear habitat with reported human-grizzly bear conflicts during 1986-2001. We based our analysis on a survey of 61 of 64 livestock producers in our study in the Rocky Mountain East Front, Montana. With the assistance of livestock and honey producers, we mapped the locations of cattle and sheep pastures, boneyards, and beehives. We used density surface mapping to identify seasonal clusters of conflicts that we term conflict hotspots. Hotspots accounted for 75% of all conflicts and encompassed approximately 8% of the study area. We also differentiated chronic (4 or more years of conflicts) from non-chronic hotspots (fewer than 4 years of conflict). The 10 chronic hotpots accounted for 58% of all conflicts. Based on Monte Carlo simulations, we found that conflict locations were most strongly associated with rivers and creeks followed by sheep lambing areas and fall sheep pastures. Conflicts also were associated with cattle calving areas, spring cow-calf pastures, summer and fall cattle pastures, and boneyards. The Monte Carlo simulations indicated associations between conflict locations and unprotected beehives at specific analysis scales. Protected (fenced) beehives were less likely to experience conflicts than unprotected beehives. Conflicts occurred at a greater rate in riparian and wetland vegetation than would be expected. The majority of conflicts occurred in a small portion of the study area, where concentrations of attractants existed that overlapped with bear habitat. These hotspots should be the target of management and conservation efforts that focus on removing or protecting attractants using non-lethal techniques.

Synthesis multi-projector content for multi-projector three dimension display using a layered representation

NASA Astrophysics Data System (ADS)

Qin, Chen; Ren, Bin; Guo, Longfei; Dou, Wenhua

2014-11-01

Multi-projector three dimension display is a promising multi-view glass-free three dimension (3D) display technology, can produce full colour high definition 3D images on its screen. One key problem of multi-projector 3D display is how to acquire the source images of projector array while avoiding pseudoscopic problem. This paper analysis the displaying characteristics of multi-projector 3D display first and then propose a projector content synthetic method using tetrahedral transform. A 3D video format that based on stereo image pair and associated disparity map is presented, it is well suit for any type of multi-projector 3D display and has advantage in saving storage usage. Experiment results show that our method solved the pseudoscopic problem.

Hölder Regularity of the 2D Dual Semigeostrophic Equations via Analysis of Linearized Monge-Ampère Equations

NASA Astrophysics Data System (ADS)

Le, Nam Q.

2018-05-01

We obtain the Hölder regularity of time derivative of solutions to the dual semigeostrophic equations in two dimensions when the initial potential density is bounded away from zero and infinity. Our main tool is an interior Hölder estimate in two dimensions for an inhomogeneous linearized Monge-Ampère equation with right hand side being the divergence of a bounded vector field. As a further application of our Hölder estimate, we prove the Hölder regularity of the polar factorization for time-dependent maps in two dimensions with densities bounded away from zero and infinity. Our applications improve previous work by G. Loeper who considered the cases of densities sufficiently close to a positive constant.

Strange attractors in weakly turbulent Couette-Taylor flow

NASA Technical Reports Server (NTRS)

Brandstater, A.; Swinney, Harry L.

1987-01-01

An experiment is conducted on the transition from quasi-periodic to weakly turbulent flow of a fluid contained between concentric cylinders with the inner cylinder rotating and the outer cylinder at rest. Power spectra, phase-space portraits, and circle maps obtained from velocity time-series data indicate that the nonperiodic behavior observed is deterministic, that is, it is described by strange attractors. Various problems that arise in computing the dimension of strange attractors constructed from experimental data are discussed and it is shown that these problems impose severe requirements on the quantity and accuracy of data necessary for determining dimensions greater than about 5. In the present experiment the attractor dimension increases from 2 at the onset of turbulence to about 4 at a Reynolds number 50-percent above the onset of turbulence.

Double-black-hole solutions of the Einstein-Maxwell-dilaton theory in five dimensions

NASA Astrophysics Data System (ADS)

Stelea, Cristian

2018-01-01

We describe a solution-generating technique that maps a static charged solution of the Einstein-Maxwell theory in four (or five) dimensions to a five-dimensional solution of the Einstein-Maxwell-Dilaton theory. As examples of this technique first we show how to construct the dilatonic version of the Reissner-Nordström solution in five dimensions and then we consider the more general case of the double black hole solutions and describe some of their properties. We found that in the general case the value of the conical singularities in between the black holes is affected by the dilaton's coupling constant to the gauge field and only in the particular case when all charges are proportional to the masses this dependence cancels out.

Synchronization, non-linear dynamics and low-frequency fluctuations: Analogy between spontaneous brain activity and networked single-transistor chaotic oscillators

PubMed Central

Minati, Ludovico; Chiesa, Pietro; Tabarelli, Davide; D'Incerti, Ludovico

2015-01-01

In this paper, the topographical relationship between functional connectivity (intended as inter-regional synchronization), spectral and non-linear dynamical properties across cortical areas of the healthy human brain is considered. Based upon functional MRI acquisitions of spontaneous activity during wakeful idleness, node degree maps are determined by thresholding the temporal correlation coefficient among all voxel pairs. In addition, for individual voxel time-series, the relative amplitude of low-frequency fluctuations and the correlation dimension (D2), determined with respect to Fourier amplitude and value distribution matched surrogate data, are measured. Across cortical areas, high node degree is associated with a shift towards lower frequency activity and, compared to surrogate data, clearer saturation to a lower correlation dimension, suggesting presence of non-linear structure. An attempt to recapitulate this relationship in a network of single-transistor oscillators is made, based on a diffusive ring (n = 90) with added long-distance links defining four extended hub regions. Similarly to the brain data, it is found that oscillators in the hub regions generate signals with larger low-frequency cycle amplitude fluctuations and clearer saturation to a lower correlation dimension compared to surrogates. The effect emerges more markedly close to criticality. The homology observed between the two systems despite profound differences in scale, coupling mechanism and dynamics appears noteworthy. These experimental results motivate further investigation into the heterogeneity of cortical non-linear dynamics in relation to connectivity and underline the ability for small networks of single-transistor oscillators to recreate collective phenomena arising in much more complex biological systems, potentially representing a future platform for modelling disease-related changes. PMID:25833429

Synchronization, non-linear dynamics and low-frequency fluctuations: Analogy between spontaneous brain activity and networked single-transistor chaotic oscillators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Minati, Ludovico, E-mail: lminati@ieee.org, E-mail: ludovico.minati@unitn.it, E-mail: lminati@istituto-besta.it; Center for Mind/Brain Sciences, University of Trento, Trento; Chiesa, Pietro

In this paper, the topographical relationship between functional connectivity (intended as inter-regional synchronization), spectral and non-linear dynamical properties across cortical areas of the healthy human brain is considered. Based upon functional MRI acquisitions of spontaneous activity during wakeful idleness, node degree maps are determined by thresholding the temporal correlation coefficient among all voxel pairs. In addition, for individual voxel time-series, the relative amplitude of low-frequency fluctuations and the correlation dimension (D{sub 2}), determined with respect to Fourier amplitude and value distribution matched surrogate data, are measured. Across cortical areas, high node degree is associated with a shift towards lower frequencymore » activity and, compared to surrogate data, clearer saturation to a lower correlation dimension, suggesting presence of non-linear structure. An attempt to recapitulate this relationship in a network of single-transistor oscillators is made, based on a diffusive ring (n = 90) with added long-distance links defining four extended hub regions. Similarly to the brain data, it is found that oscillators in the hub regions generate signals with larger low-frequency cycle amplitude fluctuations and clearer saturation to a lower correlation dimension compared to surrogates. The effect emerges more markedly close to criticality. The homology observed between the two systems despite profound differences in scale, coupling mechanism and dynamics appears noteworthy. These experimental results motivate further investigation into the heterogeneity of cortical non-linear dynamics in relation to connectivity and underline the ability for small networks of single-transistor oscillators to recreate collective phenomena arising in much more complex biological systems, potentially representing a future platform for modelling disease-related changes.« less

Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1

DOE PAGES

Lee, Ho-Hsien; Cherni, Irene; Yu, HongQi; ...

2014-08-20

CTB-MPR is a fusion protein between the B subunit of cholera toxin (CTB) and the membrane-proximal region of gp41 (MPR), the transmembrane envelope protein of Human immunodeficiency virus 1 (HIV-1), and has previously been shown to induce the production of anti-HIV-1 antibodies with antiviral functions. To further improve the design of this candidate vaccine, X-ray crystallography experiments were performed to obtain structural information about this fusion protein. Several variants of CTB-MPR were designed, constructed and recombinantly expressed in Escherichia coli . The first variant contained a flexible GPGP linker between CTB and MPR, and yielded crystals that diffracted to amore » resolution of 2.3 Å, but only the CTB region was detected in the electron-density map. A second variant, in which the CTB was directly attached to MPR, was shown to destabilize pentamer formation. A third construct containing a polyalanine linker between CTB and MPR proved to stabilize the pentameric form of the protein during purification. The purification procedure was shown to produce a homogeneously pure and monodisperse sample for crystallization. Initial crystallization experiments led to pseudo-crystals which were ordered in only two dimensions and were disordered in the third dimension. Nanocrystals obtained using the same precipitant showed promising X-ray diffraction to 5 Å resolution in femtosecond nanocrystallography experiments at the Linac Coherent Light Source at the SLAC National Accelerator Laboratory. The results demonstrate the utility of femtosecond X-ray crystallography to enable structural analysis based on nano/microcrystals of a protein for which no macroscopic crystals ordered in three dimensions have been observed before.« less

Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Ho-Hsien; Cherni, Irene; Yu, HongQi

CTB-MPR is a fusion protein between the B subunit of cholera toxin (CTB) and the membrane-proximal region of gp41 (MPR), the transmembrane envelope protein of Human immunodeficiency virus 1 (HIV-1), and has previously been shown to induce the production of anti-HIV-1 antibodies with antiviral functions. To further improve the design of this candidate vaccine, X-ray crystallography experiments were performed to obtain structural information about this fusion protein. Several variants of CTB-MPR were designed, constructed and recombinantly expressed in Escherichia coli . The first variant contained a flexible GPGP linker between CTB and MPR, and yielded crystals that diffracted to amore » resolution of 2.3 Å, but only the CTB region was detected in the electron-density map. A second variant, in which the CTB was directly attached to MPR, was shown to destabilize pentamer formation. A third construct containing a polyalanine linker between CTB and MPR proved to stabilize the pentameric form of the protein during purification. The purification procedure was shown to produce a homogeneously pure and monodisperse sample for crystallization. Initial crystallization experiments led to pseudo-crystals which were ordered in only two dimensions and were disordered in the third dimension. Nanocrystals obtained using the same precipitant showed promising X-ray diffraction to 5 Å resolution in femtosecond nanocrystallography experiments at the Linac Coherent Light Source at the SLAC National Accelerator Laboratory. The results demonstrate the utility of femtosecond X-ray crystallography to enable structural analysis based on nano/microcrystals of a protein for which no macroscopic crystals ordered in three dimensions have been observed before.« less

High-resolution human/goat comparative map of the goat polled/intersex syndrome (PIS): the human homologue is contained in a human YAC from HSA3q23.

PubMed

Vaiman, D; Schibler, L; Oustry-Vaiman, A; Pailhoux, E; Goldammer, T; Stevanovic, M; Furet, J P; Schwerin, M; Cotinot, C; Fellous, M; Cribiu, E P

1999-02-15

The genetic and cytogenetic map around the chromosome 1 region shown to be linked with polledness and intersexuality (PIS) in the domestic goat (Capra hircus) was refined. For this purpose, a goat BAC library was systematically screened with primers from human coding sequences, scraped chromosome 1 DNA, bovine microsatellites from the region, and BAC ends. All the BACs (n = 30) were mapped by fluorescence in situ hybridization (FISH) on goat chromosome 1q41-q45. The genetic mapping of 30 new goat polymorphic markers, isolated from these BACs, made it possible to reduce the PIS interval to a region of less than 1 cM on goat chromosome 1q43. The PIS locus is now located between the two genes ATP1B and COP, which both map to 3q23 in humans. Genetic, cytogenetic, and comparative data suggest that the PIS region is now probably circumscribed to an approximately 1-Mb DNA segment for which construction of a BAC contig is in progress. In addition, a human YAC contig encompassing the blepharophimosis-ptosis-epicanthus-inversus region was mapped by FISH to goat chromosome 1q43. This human disease, mapped to HSA 3q23 and affecting the development and maintenance of ovarian function, could be a potential candidate for goat PIS. Copyright 1999 Academic Press.

Mapping the functional assessment of cancer therapy-breast (FACT-B) to the 5-level EuroQoL Group's 5-dimension questionnaire (EQ-5D-5L) utility index in a multi-ethnic Asian population.

PubMed

Cheung, Yin Bun; Luo, Nan; Ng, Raymond; Lee, Chun Fan

2014-12-12

To develop an algorithm for mapping the Functional Assessment of Cancer Therapy-Breast (FACT-B) to the 5-level EuroQoL Group's 5-dimension questionnaire (EQ-5D-5L) utility index. A survey of 238 breast cancer patients in Singapore was conducted. Models using various regression methods with or without recognizing the upper boundary of utility values at 1 were fitted to predict the EQ-5D-5L utility index based on the five subscale scores of the FACT-B. Data from a follow-up survey of these patients were used to validate the results. A model that maps the physical, emotional, functional well-being and the breast cancer concerns subscales of the FACT-B to the EQ-5D-5L utility index was derived. The social well-being subscale was not associated to the utility index. Although theoretical assumptions may not be valid, ordinary least square outperformed other regression methods. The mean predicted utility index within each performance status level at follow-up deviated from the observed mean less than the minimally important difference of EQ-5D for cancer patients. The mapping algorithm converts the FACT-B to the EQ-5D utility index. This enables oncologists, clinical researchers and policy makers to obtain a quantitative utility summary of a patient's health status when only the FACT-B is assessed.

Physical-mechanical image of the cell surface on the base of AFM data in contact mode

NASA Astrophysics Data System (ADS)

Starodubtseva, M. N.; Starodubtsev, I. E.; Yegorenkov, N. I.; Kuzhel, N. S.; Konstantinova, E. E.; Chizhik, S. A.

2017-10-01

Physical and mechanical properties of the cell surface are well-known markers of a cell state. The complex of the parameters characterizing the cell surface properties, such as the elastic modulus (E), the parameters of adhesive (Fa), and friction (Ff) forces can be measured using atomic force microscope (AFM) in a contact mode and form namely the physical-mechanical image of the cell surface that is a fundamental element of the cell mechanical phenotype. The paper aims at forming the physical-mechanical images of the surface of two types of glutaraldehyde-fixed cancerous cells (human epithelial cells of larynx carcinoma, HEp-2c cells, and breast adenocarcinoma, MCF-7 cells) based on the data obtained by AFM in air and revealing the basic difference between them. The average values of friction, elastic and adhesive forces, and the roughness of lateral force maps, as well as dependence of the fractal dimension of lateral force maps on Z-scale factor have been studied. We have revealed that the response of microscale areas of the HEp-2c cell surface having numerous microvilli to external mechanical forces is less expressed and more homogeneous in comparison with the response of MCF-7 cell surface.

Health impacts of an environmental disaster: a polemic

NASA Astrophysics Data System (ADS)

Dorling, Danny; Barford, Anna; Wheeler, Ben

2007-10-01

At this early point in the 21st century a major concern that we face is the future possible effects of people-induced global warming. The predicted effects are severe, but argued by some to be avoidable if we act now. Here we consider the dimensions of another disaster: one for which not only the causes, but also their horrific consequences, are current worldwide. The implicit question is 'why are we more worried about future disasters than those already occurring?' The worldmapper collection of cartograms (where a map is used like a pie-chart to present data) is used here to illustrate the extent of international inequalities in health and living conditions, discussed in relation to other aspects of human lives. Though the shape that we can see the world is in is shocking, we can also envisage a positive future. We compare these current global times to more local past times experienced during the ravaging inequalities of Victorian Britain. We use Britain simply as an example. We end by suggesting a further step the current British Prime Minister could make in his thinking. Doing this we can see the potential for environmental reconstruction, which would result (as it did before) in considerable reductions in infant mortality. Our common future is not already mapped out; it is still to be won.

Does the 'diffusion of innovations' model enrich understanding of research use? Case studies of the implementation of thrombolysis services for stroke.

PubMed

Boaz, Annette; Baeza, Juan; Fraser, Alec

2016-10-01

To test whether the model of 'diffusion of innovations' enriches understanding of the implementation of evidence-based thrombolysis services for stroke patients. Four case studies of the implementation of evidence on thrombolysis in stroke services in England and Sweden. Semistructured interviews with 95 staff including doctors, nurses and managers working in stroke units, emergency medicine, radiology, the ambulance service, community rehabilitation services and commissioners. The implementation of thrombolysis in acute stroke management benefited from a critical mass of the factors featured in the model including: the support of national and local opinion leaders; a strong evidence base and financial incentives. However, while the model provided a starting point as an organizational framework for mapping the critical factors influencing implementation, to understand properly the process of implementation and the importance of the different factors identified, more detailed analyses of context and, in particular, of the human and social dimensions of change was needed. While recognising the usefulness of the model of diffusion of innovations in mapping the processes by which diffusion occurs, the use of methods that lend themselves to in-depth analysis, such as ethnography and the application of relevant bodies of social theory, are needed. © The Author(s) 2016.

The World Spatiotemporal Analytics and Mapping Project (WSTAMP): Further Progress in Discovering, Exploring, and Mapping Spatiotemporal Patterns Across the World's Largest Open Source Data Sets

NASA Astrophysics Data System (ADS)

Piburn, J.; Stewart, R.; Myers, A.; Sorokine, A.; Axley, E.; Anderson, D.; Burdette, J.; Biddle, C.; Hohl, A.; Eberle, R.; Kaufman, J.; Morton, A.

2017-10-01

Spatiotemporal (ST) analytics applied to major data sources such as the World Bank and World Health Organization has shown tremendous value in shedding light on the evolution of cultural, health, economic, and geopolitical landscapes on a global level. WSTAMP engages this opportunity by situating analysts, data, and analytics together within a visually rich and computationally rigorous online analysis environment. Since introducing WSTAMP at the First International Workshop on Spatiotemporal Computing, several transformative advances have occurred. Collaboration with human computer interaction experts led to a complete interface redesign that deeply immerses the analyst within a ST context, significantly increases visual and textual content, provides navigational crosswalks for attribute discovery, substantially reduce mouse and keyboard actions, and supports user data uploads. Secondly, the database has been expanded to include over 16,000 attributes, 50 years of time, and 200+ nation states and redesigned to support non-annual, non-national, city, and interaction data. Finally, two new analytics are implemented for analyzing large portfolios of multi-attribute data and measuring the behavioral stability of regions along different dimensions. These advances required substantial new approaches in design, algorithmic innovations, and increased computational efficiency. We report on these advances and inform how others may freely access the tool.

Unitary Operators on the Document Space.

ERIC Educational Resources Information Center

Hoenkamp, Eduard

2003-01-01

Discusses latent semantic indexing (LSI) that would allow search engines to reduce the dimension of the document space by mapping it into a space spanned by conceptual indices. Topics include vector space models; singular value decomposition (SVD); unitary operators; the Haar transform; and new algorithms. (Author/LRW)

Stability and perturbations of countable Markov maps

NASA Astrophysics Data System (ADS)

Jordan, Thomas; Munday, Sara; Sahlsten, Tuomas

2018-04-01

Let T and , , be countable Markov maps such that the branches of converge pointwise to the branches of T, as . We study the stability of various quantities measuring the singularity (dimension, Hölder exponent etc) of the topological conjugacy between and T when . This is a well-understood problem for maps with finitely-many branches, and the quantities are stable for small ɛ, that is, they converge to their expected values if . For the infinite branch case their stability might be expected to fail, but we prove that even in the infinite branch case the quantity is stable under some natural regularity assumptions on and T (under which, for instance, the Hölder exponent of fails to be stable). Our assumptions apply for example in the case of Gauss map, various Lüroth maps and accelerated Manneville-Pomeau maps when varying the parameter α. For the proof we introduce a mass transportation method from the cusp that allows us to exploit thermodynamical ideas from the finite branch case. Dedicated to the memory of Bernd O Stratmann

A terracing operator for physical property mapping with potential field data

USGS Publications Warehouse

Cordell, L.; McCafferty, A.E.

1989-01-01

The terracing operator works iteratively on gravity or magnetic data, using the sense of the measured field's local curvature, to produce a field comprised of uniform domains separated by abrupt domain boundaries. The result is crudely proportional to a physical-property function defined in one (profile case) or two (map case) horizontal dimensions. This result can be extended to a physical-property model if its behavior in the third (vertical) dimension is defined, either arbitrarily or on the basis of the local geologic situation. The terracing algorithm is computationally fast and appropriate to use with very large digital data sets. The terracing operator was applied separately to aeromagnetic and gravity data from a 136km x 123km area in eastern Kansas. Results provide a reasonable good physical representation of both the gravity and the aeromagnetic data. Superposition of the results from the two data sets shows many areas of agreement that can be referenced to geologic features within the buried Precambrian crystalline basement. -from Authors

A new method for mapping multidimensional data to lower dimensions

NASA Technical Reports Server (NTRS)

Gowda, K. C.

1983-01-01

A multispectral mapping method is proposed which is based on the new concept of BEND (Bidimensional Effective Normalised Difference). The method, which involves taking one sample point at a time and finding the interrelationships between its features, is found very economical from the point of view of storage and processing time. It has good dimensionality reduction and clustering properties, and is highly suitable for computer analysis of large amounts of data. The transformed values obtained by this procedure are suitable for either a planar 2-space mapping of geological sample points or for making grayscale and color images of geo-terrains. A few examples are given to justify the efficacy of the proposed procedure.

[Biopsychosocial understanding of human sexuality. Prerequisite for diagnostics and treatment in sexual medicine].

PubMed

Beier, K M

2006-08-01

Sexual medicine is a subdiscipline of clinical medicine that deals with human sexuality and disorders. Sexuality eludes a unilateral definition. As a biologically, psychologically, and socially determined experience dimension of the human being, its individual form depends on biological factors and developments in the person's life. Moreover, sexuality exhibits different dimensions--lust, reproduction, and relationship--that are indeed closely interrelated. For this reason, directing therapy at only one of these dimensions is not adequate. All human beings are programmed toward fulfillment of elementary biopsychosocial needs such as acceptance, closeness, warmth, and security. If these basic needs are shortchanged in terms of fulfillment, all sorts of restrictions in the quality of life ensue, even to the point of resultant disorders of sexual function. Treatment then approaches the roots when it does not center on the sexual dysfunction but rather on the underlying frustrated relationship of the partners. Syndyastic sexual therapy is an important treatment method in sexual medicine.

Fear-conditioning mechanisms associated with trait vulnerability to anxiety in humans.

PubMed

Indovina, Iole; Robbins, Trevor W; Núñez-Elizalde, Anwar O; Dunn, Barnaby D; Bishop, Sonia J

2011-02-10

Investigations of fear conditioning in rodents and humans have illuminated the neural mechanisms underlying cued and contextual fear. A critical question is how personality dimensions such as trait anxiety act through these mechanisms to confer vulnerability to anxiety disorders, and whether humans' ability to overcome acquired fears depends on regulatory skills not characterized in animal models. In a neuroimaging study of fear conditioning in humans, we found evidence for two independent dimensions of neurocognitive function associated with trait vulnerability to anxiety. The first entailed increased amygdala responsivity to phasic fear cues. The second involved impoverished ventral prefrontal cortical (vPFC) recruitment to downregulate both cued and contextual fear prior to omission (extinction) of the aversive unconditioned stimulus. These two dimensions may contribute to symptomatology differences across anxiety disorders; the amygdala mechanism affecting the development of phobic fear and the frontal mechanism influencing the maintenance of both specific fears and generalized anxiety. Copyright © 2011 Elsevier Inc. All rights reserved.

Parietal and superior frontal visuospatial maps activated by pointing and saccades

PubMed Central

Hagler, D.J.; Riecke, L.; Sereno, M.I.

2009-01-01

A recent study from our laboratory demonstrated that parietal cortex contains a map of visual space related to saccades and spatial attention and identified this area as the likely human homologue of the lateral intraparietal (LIP). A human homologue for the parietal reach region (PRR), thought to preferentially encode planned hand movements, has also been recently proposed. Both of these areas, originally identified in the macaque monkey, have been shown to encode space with eye-centered coordinates. Functional magnetic resonance imaging (fMRI) of humans was used to test the hypothesis that the putative human PRR contains a retinotopic map recruited by finger pointing but not saccades and to test more generally for differences in the visuospatial maps recruited by pointing and saccades. We identified multiple maps in both posterior parietal cortex and superior frontal cortex recruited for eye and hand movements, including maps not observed in previous mapping studies. Pointing and saccade maps were generally consistent within single subjects. We have developed new group analysis methods for phase-encoded data, which revealed subtle differences between pointing and saccades, including hemispheric asymmetries, but we did not find evidence of pointing-specific maps of visual space. PMID:17376706

Collective Behaviors in Spatially Extended Systems with Local Interactions and Synchronous Updating

NASA Astrophysics Data System (ADS)

ChatÉ, H.; Manneville, P.

1992-01-01

Assessing the extent to which dynamical systems with many degrees of freedom can be described within a thermodynamics formalism is a problem that currently attracts much attention. In this context, synchronously updated regular lattices of identical, chaotic elements with local interactions are promising models for which statistical mechanics may be hoped to provide some insights. This article presents a large class of cellular automata rules and coupled map lattices of the above type in space dimensions d = 2 to 6.Such simple models can be approached by a mean-field approximation which usually reduces the dynamics to that of a map governing the evolution of some extensive density. While this approximation is exact in the d = infty limit, where macroscopic variables must display the time-dependent behavior of the mean-field map, basic intuition from equilibrium statistical mechanics rules out any such behavior in a low-dimensional systems, since it would involve the collective motion of locally disordered elements.The models studied are chosen to be as close as possible to mean-field conditions, i.e., rather high space dimension, large connectivity, and equal-weight coupling between sites. While the mean-field evolution is never observed, a new type of non-trivial collective behavior is found, at odds with the predictions of equilibrium statistical mechanics. Both in the cellular automata models and in the coupled map lattices, macroscopic variables frequently display a non-transient, time-dependent, low-dimensional dynamics emerging out of local disorder. Striking examples are period 3 cycles in two-state cellular automata and a Hopf bifurcation for a d = 5 lattice of coupled logistic maps. An extensive account of the phenomenology is given, including a catalog of behaviors, classification tables for the celular automata rules, and bifurcation diagrams for the coupled map lattices.The observed underlying dynamics is accompanied by an intrinsic quasi-Gaussian noise (stemming from the local disorder) which disappears in the infinite-size limit. The collective behaviors constitute a robust phenomenon, resisting external noise, small changes in the local dynamics, and modifications of the initial and boundary conditions. Synchronous updating, high space dimension and the regularity of connections are shown to be crucial ingredients in the subtle build-up of correlations giving rise to the collective motion. The discussion stresses the need for a theoretical understanding that neither equilibrium statistical mechanics nor higher-order mean-field approximations are able to provide.

Clinical concept mapping: Does it improve discipline-based critical thinking of nursing students?

PubMed Central

Moattari, Marzieh; Soleimani, Sara; Moghaddam, Neda Jamali; Mehbodi, Farkhondeh

2014-01-01

Background: Enhancing nursing students’ critical thinking is a challenge faced by nurse educators. This study aimed at determining the effect of clinical concept mapping on discipline-based critical thinking of nursing students. Materials and Methods: In this quasi-experimental post-test only design, a convenient sample of 4th year nursing students (N = 32) participated. They were randomly divided into two groups. The experimental group participated in a 1-day workshop on clinical concept mapping. They were also assigned to use at least two clinical concepts mapping during their clinical practice. Post-test was done using a specially designed package consisting of vignettes for measurement of 17 dimensions of critical thinking in nursing under two categories of cognitive critical thinking skills and habits of mind. They were required to write about how they would use a designated critical thinking skills or habits of mind to accomplish the nursing actions. The students’ responses were evaluated based on identification of critical thinking, justification, and quality of the student's response. The mean score of both groups was compared by Mann-Whitney test using SPSS version 16.5. Results: The results of the study revealed a significant difference between the two groups’ critical thinking regarding identification, justification, and quality of responses, and overall critical thinking scores, cognitive thinking skills, and habits of mind. The two groups also differed significantly from each other in 11 out of 17 dimensions of critical thinking. Conclusion: Clinical concept mapping is a valuable strategy for improvement of critical thinking of nursing students. However, further studies are recommended to generalize this result to nursing students in their earlier stage of education. PMID:24554963

The National 3-D Geospatial Information Web-Based Service of Korea

NASA Astrophysics Data System (ADS)

Lee, D. T.; Kim, C. W.; Kang, I. G.

2013-09-01

3D geospatial information systems should provide efficient spatial analysis tools and able to use all capabilities of the third dimension, and a visualization. Currently, many human activities make steps toward the third dimension like land use, urban and landscape planning, cadastre, environmental monitoring, transportation monitoring, real estate market, military applications, etc. To reflect this trend, the Korean government has been started to construct the 3D geospatial data and service platform. Since the geospatial information was introduced in Korea, the construction of geospatial information (3D geospatial information, digital maps, aerial photographs, ortho photographs, etc.) has been led by the central government. The purpose of this study is to introduce the Korean government-lead 3D geospatial information web-based service for the people who interested in this industry and we would like to introduce not only the present conditions of constructed 3D geospatial data but methodologies and applications of 3D geospatial information. About 15% (about 3,278.74 km2) of the total urban area's 3D geospatial data have been constructed by the national geographic information institute (NGII) of Korea from 2005 to 2012. Especially in six metropolitan cities and Dokdo (island belongs to Korea) on level of detail (LOD) 4 which is photo-realistic textured 3D models including corresponding ortho photographs were constructed in 2012. In this paper, we represented web-based 3D map service system composition and infrastructure and comparison of V-world with Google Earth service will be presented. We also represented Open API based service cases and discussed about the protection of location privacy when we construct 3D indoor building models. In order to prevent an invasion of privacy, we processed image blurring, elimination and camouflage. The importance of public-private cooperation and advanced geospatial information policy is emphasized in Korea. Thus, the progress of spatial information industry of Korea is expected in the near future.

The Challenge of Human Spermatozoa Proteome: A Systematic Review.

PubMed

Gilany, Kambiz; Minai-Tehrani, Arash; Amini, Mehdi; Agharezaee, Niloofar; Arjmand, Babak

2017-01-01

Currently, there are 20,197 human protein-coding genes in the most expertly curated database (UniProtKB/Swiss-Pro). Big efforts have been made by the international consortium, the Chromosome-Centric Human Proteome Project (C-HPP) and independent researchers, to map human proteome. In brief, anno 2017 the human proteome was outlined. The male factor contributes to 50% of infertility in couples. However, there are limited human spermatozoa proteomic studies. Firstly, the development of the mapping of the human spermatozoa was analyzed. The human spermatozoa have been used as a model for missing proteins. It has been shown that human spermatozoa are excellent sources for finding missing proteins. Y chromosome proteome mapping is led by Iran. However, it seems that it is extremely challenging to map the human spermatozoa Y chromosome proteins based on current mass spectrometry-based proteomics technology. Post-translation modifications (PTMs) of human spermatozoa proteome are the most unexplored area and currently the exact role of PTMs in male infertility is unknown. Additionally, the clinical human spermatozoa proteomic analysis, anno 2017 was done in this study.

Differential impact of relevant and irrelevant dimension primes on rule-based and information-integration category learning.

PubMed

Grimm, Lisa R; Maddox, W Todd

2013-11-01

Research has identified multiple category-learning systems with each being "tuned" for learning categories with different task demands and each governed by different neurobiological systems. Rule-based (RB) classification involves testing verbalizable rules for category membership while information-integration (II) classification requires the implicit learning of stimulus-response mappings. In the first study to directly test rule priming with RB and II category learning, we investigated the influence of the availability of information presented at the beginning of the task. Participants viewed lines that varied in length, orientation, and position on the screen, and were primed to focus on stimulus dimensions that were relevant or irrelevant to the correct classification rule. In Experiment 1, we used an RB category structure, and in Experiment 2, we used an II category structure. Accuracy and model-based analyses suggested that a focus on relevant dimensions improves RB task performance later in learning while a focus on an irrelevant dimension improves II task performance early in learning. © 2013.

Simulations of star-forming molecular clouds: observational predictions

NASA Astrophysics Data System (ADS)

Zhang, Shangjia; Hartmann, Lee; Kuznetsova, Aleksandra; Abelardo Zamora, Manuel

2018-01-01

Observations of protostellar molecular cloud cores can be used to test theories of star formation. However, observational results can be biased because of limited information: (a) only two spatial dimensions and one velocity dimension can be measured, (b) and cores generally are not spherically symmetric. We use numerical simulations of the formation and collapse of molecular gas with sink particles to make observational predictions. We use the radiative transfer code LIME to predict CO and NH3 channel maps. We find reasonable agreement with observed velocity structures and gradients but occasional large differences depending on viewing angle.

A comparative analysis of the categorization of multidimensional stimuli: I. Unidimensional classification does not necessarily imply analytic processing; evidence from pigeons (Columba livia), squirrels (Sciurus carolinensis), and humans (Homo sapiens).

PubMed

Wills, A J; Lea, Stephen E G; Leaver, Lisa A; Osthaus, Britta; Ryan, Catriona M E; Suret, Mark B; Bryant, Catherine M L; Chapman, Sue J A; Millar, Louise

2009-11-01

Pigeons (Columba livia), gray squirrels (Sciurus carolinensis), and undergraduates (Homo sapiens) learned discrimination tasks involving multiple mutually redundant dimensions. First, pigeons and undergraduates learned conditional discriminations between stimuli composed of three spatially separated dimensions, after first learning to discriminate the individual elements of the stimuli. When subsequently tested with stimuli in which one of the dimensions took an anomalous value, the majority of both species categorized test stimuli by their overall similarity to training stimuli. However some individuals of both species categorized them according to a single dimension. In a second set of experiments, squirrels, pigeons, and undergraduates learned go/no-go discriminations using multiple simultaneous presentations of stimuli composed of three spatially integrated, highly salient dimensions. The tendency to categorize test stimuli including anomalous dimension values unidimensionally was higher than in the first set of experiments and did not differ significantly between species. The authors conclude that unidimensional categorization of multidimensional stimuli is not diagnostic for analytic cognitive processing, and that any differences between human's and pigeons' behavior in such tasks are not due to special features of avian visual cognition.

A Mobile, Map-Based Tasking Interface for Human-Robot Interaction

DTIC Science & Technology

2010-12-01

A MOBILE, MAP-BASED TASKING INTERFACE FOR HUMAN-ROBOT INTERACTION By Eli R. Hooten Thesis Submitted to the Faculty of the Graduate School of...SUBTITLE A Mobile, Map-Based Tasking Interface for Human-Robot Interaction 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...3 II.1 Interactive Modalities and Multi-Touch . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 II.2

Concept Maps: Practice Applications in Adult Education and Human Resource Development

ERIC Educational Resources Information Center

Daley, Barbara J.

2010-01-01

Concept maps can be used as both a cognitive and constructivist learning strategy in teaching and learning in adult education and human resource development. The maps can be used to understand course readings, analyze case studies, develop reflective thinking and enhance research skills. The creation of concept maps can also be supported by the…

(Un)Fixing Education

ERIC Educational Resources Information Center

Kuntz, Aaron M.; Petrovic, John E.

2018-01-01

In this article we consider the material dimensions of schooling as constitutive of the possibilities inherent in "fixing" education. We begin by mapping out the problem of "fixing education," pointing to the necrophilic tendencies of contemporary education--a desire to kill what otherwise might be life-giving. In this sense,…

A Study of Student Perceptions of Exemplary Instruction and Servant Leader Behavioral Qualities

ERIC Educational Resources Information Center

Setliff, Richard C., Jr.

2014-01-01

This study examined students' perceptions of certain servant leader behaviors associated with either typical or outstanding instruction. Five servant leadership dimensions were considered: altruistic calling, emotional healing, wisdom, persuasive mapping, and organizational stewardship. Two groups of 300 students attending a midsized university…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Müller-Hermes, Alexander, E-mail: muellerh@ma.tum.de; Wolf, Michael M., E-mail: m.wolf@tum.de; Reeb, David, E-mail: reeb.qit@gmail.com

We investigate linear maps between matrix algebras that remain positive under tensor powers, i.e., under tensoring with n copies of themselves. Completely positive and completely co-positive maps are trivial examples of this kind. We show that for every n ∈ ℕ, there exist non-trivial maps with this property and that for two-dimensional Hilbert spaces there is no non-trivial map for which this holds for all n. For higher dimensions, we reduce the existence question of such non-trivial “tensor-stable positive maps” to a one-parameter family of maps and show that an affirmative answer would imply the existence of non-positive partial transposemore » bound entanglement. As an application, we show that any tensor-stable positive map that is not completely positive yields an upper bound on the quantum channel capacity, which for the transposition map gives the well-known cb-norm bound. We, furthermore, show that the latter is an upper bound even for the local operations and classical communications-assisted quantum capacity, and that moreover it is a strong converse rate for this task.« less

ECK, a human EPH-related gene, maps to 1p36.1, a common region of alteration in human cancers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sulman, E.P.; Brodeur, G.M.; Ikegaki, N.

1997-03-01

Mouse eck, a member of the EPH gene family, has been mapped to mouse chromosome 4. The syntenic relationship between this chromosome and human chromosome 1 suggests that the human ECK gene maps to the distal short arm of human chromosome 1 (1p). Since this region is frequently deleted or altered in certain tumors of neuroectodermal origin, it is important to define the specific chromosomal localization of the human ECK gene. PCR screening of a rodent-human somatic cell hybrid panel by ECK-specific primers showed that ECK is indeed localized to human chromosome 1. Additional PCR screening of a regional screeningmore » panel for chromosome 1p indicated that ECK is localized to 1p36, distal to FUCA1. Furthermore, fluorescence in situ hybridization analysis with an ECK-specific P1 clone showed that ECK maps proximal to genetic marker D1S228. Taken together, the data suggest that ECK maps to 1p36.1, a region that is frequently deleted in neuroblastoma, melanoma, and other neuroectodermal tumors. 23 refs., 3 figs.« less

A physically based criterion for hydraulic hazard mapping

NASA Astrophysics Data System (ADS)

Milanesi, Luca; Pilotti, Marco; Petrucci, Olga

2013-04-01

Hydraulic hazard maps are widely used for land use and emergency planning. Due to their practical consequences, it is important that their meaning is effectively transferred and shared by the stakeholders; to this purpose maps should communicate hazard levels moving from the potential consequences on specified targets. For these reasons flood maps showing only the extension of the inundated areas or flow features as depth and/or velocity may reveal themselves as ineffective instruments. The selection of the specific target to analyse must, in our opinion, be site-specific and reflect land use and/or the hydraulics features of the phenomenon. In case of sudden processes, such as torrential floods or debris flows, hazard levels should be referred to human life, because emergency plans may not mitigate risk; on the contrary, when the time scale of the flood wave propagation is sufficiently larger than the warning system one, the focus might move to the economic value of properties, since human-focused criteria may result in too severe land planning restrictions. This contribution starts exploring, from a theoretical point of view, human hazard levels as drowning, toppling and friction stability limits, which are the main failure mechanisms of human stability in flows. The proposed approach considers the human body, set on a slope and hit by a current of known density, as a combination of cylinders with different dimensions. The drowning threshold is identified through a limiting water depth, while toppling and translation are studied respectively through a moment and momentum balance. The involved forces are the friction at the bottom, the destabilizing drag force exerted by the current, the human weight and buoyancy. Several threshold curves on the velocity-depth plane can be identified as a function of different masses and heights for children and adults. Because of its dependence from the fluid density, this methodology may be applied also to define hazard thresholds for debris flows if the simplification of considering the presence of debris through an augmented density of the fluid continuum is accepted. This methodology, which fits with most literature experimental dataset for both adults and children impacted by a flood, is then tested with historical data concerning flood events truly occurred in the past. Data have been mined from a historical database containing approximately 11000 records concerning the effects of hydro-meteorological events occurred in Calabria (southern Italy) since 19th century, selecting only the events where people were directly involved. These data come from different sources as newspapers, archives of national and regional agencies, scientific and technical reports, on-site surveys reports and information collected by interviewing both involved people and local administrators. Dealing with descriptive information of events occurred in different historical periods and morpho-climatic sectors of the region, the quantities required to implement the model can be found in a limited number of recent cases. In order to widen the data set that can be used to validate the proposed methodology, we explore some approaches to indirectly assess the parameters required to implement the model.

Helical image reconstruction of the outward-open human erythrocyte band 3 membrane domain in tubular crystals.

PubMed

Yamaguchi, Tomohiro; Fujii, Takashi; Abe, Yoshito; Hirai, Teruhisa; Kang, Dongchon; Namba, Keiichi; Hamasaki, Naotaka; Mitsuoka, Kaoru

2010-03-01

The C-terminal membrane domain of erythrocyte band 3 functions as an anion exchanger. Here, we report the three-dimensional (3D) structure of the membrane domain in an inhibitor-stabilized, outward-open conformation at 18A resolution. Unstained, frozen-hydrated tubular crystals containing the membrane domain of band 3 purified from human red blood cells (hB3MD) were examined using cryo-electron microscopy and iterative helical real-space reconstruction (IHRSR). The 3D image reconstruction of the tubular crystals showed the molecular packing of hB3MD dimers with dimensions of 60 x 110 A in the membrane plane and a thickness of 70A across the membrane. Immunoelectron microscopy and carboxyl-terminal digestion demonstrated that the intracellular surface of hB3MD was exposed on the outer surface of the tubular crystal. A 3D density map revealed that hB3MD consists of at least two subdomains and that the outward-open form is characterized by a large hollow area on the extracellular surface and continuous density on the intracellular surface. (c) 2009 Elsevier Inc. All rights reserved.

Human pose tracking from monocular video by traversing an image motion mapped body pose manifold

NASA Astrophysics Data System (ADS)

Basu, Saurav; Poulin, Joshua; Acton, Scott T.

2010-01-01

Tracking human pose from monocular video sequences is a challenging problem due to the large number of independent parameters affecting image appearance and nonlinear relationships between generating parameters and the resultant images. Unlike the current practice of fitting interpolation functions to point correspondences between underlying pose parameters and image appearance, we exploit the relationship between pose parameters and image motion flow vectors in a physically meaningful way. Change in image appearance due to pose change is realized as navigating a low dimensional submanifold of the infinite dimensional Lie group of diffeomorphisms of the two dimensional sphere S2. For small changes in pose, image motion flow vectors lie on the tangent space of the submanifold. Any observed image motion flow vector field is decomposed into the basis motion vector flow fields on the tangent space and combination weights are used to update corresponding pose changes in the different dimensions of the pose parameter space. Image motion flow vectors are largely invariant to style changes in experiments with synthetic and real data where the subjects exhibit variation in appearance and clothing. The experiments demonstrate the robustness of our method (within +/-4° of ground truth) to style variance.

N-acetylcysteine attenuates TNF-α-induced p38 MAP kinase activation and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells

PubMed Central

Hashimoto, Shu; Gon, Yasuhiro; Matsumoto, Ken; Takeshita, Ikuko; Horie, Takashi

2001-01-01

We have previously shown that tumour necrosis factor-α (TNF-α) activates p38 mitogen-activated protein (MAP) kinase to produce interleukin-8 (IL-8) by human pulmonary vascular endothelial cells. Reactive oxygen species (ROS) including H2O2 generated by TNF-α can act as signalling intermediates for cytokine induction; therefore, scavenging ROS by anti-oxidants is important for the regulation of cytokine production. However, the effect of N-acetylcysteine (NAC), which acts as a precursor of glutathione (GSH) synthesis, on TNF-α-induced activation of p38 MAP kinase pathway and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells has not been determined. To clarify these issues, we examined the effect of NAC on TNF-α-induced activation of p38 MAP kinase, MAP kinase kinase (MKK) 3 and MKK6 which are upstream regulators of p38 MAP kinase, and p38 MAP kinase-mediated IL-8 production. Human pulmonary vascular endothelial cells that had been preincubated with NAC were stimulated with TNF-α and then the activation of p38 MAP kinase and MKK3/MKK6 in the cells and IL-8 concentrations in the culture supernatants were determined. Intracellular GSH levels increased in NAC-treated cells. NAC attenuated TNF-α-induced activation of p38 MAP kinase and MKK3/MKK6. NAC attenuated p38 MAP kinase-mediated IL-8 production by TNF-α-stimulated cells. These results indicate that the cellular reduction and oxidation (redox) regulated by intracellular GSH is critical for TNF-α-induced activation of p38 MAP kinase pathway and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells, and we emphasize that anti-oxidant therapy is an important strategy for the treatment of acute lung injury. PMID:11156586

N-acetylcysteine attenuates TNF-alpha-induced p38 MAP kinase activation and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells.

PubMed

Hashimoto, S; Gon, Y; Matsumoto, K; Takeshita, I; Horie, T

2001-01-01

1. We have previously shown that tumour necrosis factor-alpha (TNF-alpha) activates p38 mitogen-activated protein (MAP) kinase to produce interleukin-8 (IL-8) by human pulmonary vascular endothelial cells. Reactive oxygen species (ROS) including H(2)O(2) generated by TNF-alpha can act as signalling intermediates for cytokine induction; therefore, scavenging ROS by anti-oxidants is important for the regulation of cytokine production. However, the effect of N-acetylcysteine (NAC), which acts as a precursor of glutathione (GSH) synthesis, on TNF-alpha-induced activation of p38 MAP kinase pathway and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells has not been determined. To clarify these issues, we examined the effect of NAC on TNF-alpha-induced activation of p38 MAP kinase, MAP kinase kinase (MKK) 3 and MKK6 which are upstream regulators of p38 MAP kinase, and p38 MAP kinase-mediated IL-8 production. 2. Human pulmonary vascular endothelial cells that had been preincubated with NAC were stimulated with TNF-alpha and then the activation of p38 MAP kinase and MKK3/MKK6 in the cells and IL-8 concentrations in the culture supernatants were determined. 3. Intracellular GSH levels increased in NAC-treated cells. 4. NAC attenuated TNF-alpha-induced activation of p38 MAP kinase and MKK3/MKK6. 5. NAC attenuated p38 MAP kinase-mediated IL-8 production by TNF-alpha-stimulated cells. 6. These results indicate that the cellular reduction and oxidation (redox) regulated by intracellular GSH is critical for TNF-alpha-induced activation of p38 MAP kinase pathway and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells, and we emphasize that anti-oxidant therapy is an important strategy for the treatment of acute lung injury.

Topological data analysis of contagion maps for examining spreading processes on networks.

PubMed

Taylor, Dane; Klimm, Florian; Harrington, Heather A; Kramár, Miroslav; Mischaikow, Konstantin; Porter, Mason A; Mucha, Peter J

2015-07-21

Social and biological contagions are influenced by the spatial embeddedness of networks. Historically, many epidemics spread as a wave across part of the Earth's surface; however, in modern contagions long-range edges-for example, due to airline transportation or communication media-allow clusters of a contagion to appear in distant locations. Here we study the spread of contagions on networks through a methodology grounded in topological data analysis and nonlinear dimension reduction. We construct 'contagion maps' that use multiple contagions on a network to map the nodes as a point cloud. By analysing the topology, geometry and dimensionality of manifold structure in such point clouds, we reveal insights to aid in the modelling, forecast and control of spreading processes. Our approach highlights contagion maps also as a viable tool for inferring low-dimensional structure in networks.

Topological data analysis of contagion maps for examining spreading processes on networks

NASA Astrophysics Data System (ADS)

Taylor, Dane; Klimm, Florian; Harrington, Heather A.; Kramár, Miroslav; Mischaikow, Konstantin; Porter, Mason A.; Mucha, Peter J.

2015-07-01

Social and biological contagions are influenced by the spatial embeddedness of networks. Historically, many epidemics spread as a wave across part of the Earth's surface; however, in modern contagions long-range edges--for example, due to airline transportation or communication media--allow clusters of a contagion to appear in distant locations. Here we study the spread of contagions on networks through a methodology grounded in topological data analysis and nonlinear dimension reduction. We construct `contagion maps' that use multiple contagions on a network to map the nodes as a point cloud. By analysing the topology, geometry and dimensionality of manifold structure in such point clouds, we reveal insights to aid in the modelling, forecast and control of spreading processes. Our approach highlights contagion maps also as a viable tool for inferring low-dimensional structure in networks.

Geographic Resources Analysis Support System (GRASS) Version 4.0 User’s Reference Manual

DTIC Science & Technology

1992-06-01

inpur-image need not be square; before processing, the X and Y dimensions of the input-image are padded with zeroes to the next highest power of two in...structures an input kowledge /control script with an appropriate combination of map layer category values (GRASS raster map layers that contain data on...F cos(x) cosine of x (x is in degrees) F exp(x) exponential function of x F exp(x,y) x to the power y F float(x) convert x to floating point F if

Combined visualization for noise mapping of industrial facilities based on ray-tracing and thin plate splines

NASA Astrophysics Data System (ADS)

Ovsiannikov, Mikhail; Ovsiannikov, Sergei

2017-01-01

The paper presents the combined approach to noise mapping and visualizing of industrial facilities sound pollution using forward ray tracing method and thin-plate spline interpolation. It is suggested to cauterize industrial area in separate zones with similar sound levels. Equivalent local source is defined for range computation of sanitary zones based on ray tracing algorithm. Computation of sound pressure levels within clustered zones are based on two-dimension spline interpolation of measured data on perimeter and inside the zone.

On the ⋆-PRODUCT Quantization and the Duflo Map in Three Dimensions

NASA Astrophysics Data System (ADS)

Rosa, Luigi; Vitale, Patrizia

2012-11-01

We analyze the ⋆-product induced on ℱ(ℝ3) by a suitable reduction of the Moyal product defined on ℱ(ℝ4). This is obtained through the identification ℝ3≃𝔤*, with 𝔤 a three-dimensional Lie algebra. We consider the 𝔰𝔲(2) case, exhibit a matrix basis and realize the algebra of functions on 𝔰𝔲(2)* in such a basis. The relation to the Duflo map is discussed. As an application to quantum mechanics we compute the spectrum of the hydrogen atom.

Learning to Change: New Dimensions.

ERIC Educational Resources Information Center

Loughlin, Kathleen

1996-01-01

Change involves thoughts, emotions, values, and actions but thought gets the most attention. Learning to change necessitates an integration of rational and nonrational ways of knowing. Nonrational ways and human care are important dimensions of the learning process. (SK)

Cohesion in Multinational Military Units

DTIC Science & Technology

2010-12-10

Assertiveness for Hofstede’s Masculinity dimension and added three dimensions: Humanistic , Performance, and Future Orientation. GLOBE researchers...values. It addresses the most profound existential issues of human life; e.g. freedom and inevitability, fear and faith, security and insecurity, right

An Empirical Research on the Correlation between Human Capital and Career Success of Knowledge Workers in Enterprise

NASA Astrophysics Data System (ADS)

Guo, Wenchen; Xiao, Hongjun; Yang, Xi

Human capital plays an important part in employability of knowledge workers, also it is the important intangible assets of company. This paper explores the correlation between human capital and career success of knowledge workers. Based on literature retrieval, we identified measuring tool of career success and modified further; measuring human capital with self-developed scale of high reliability and validity. After exploratory factor analysis, we suggest that human capital contents four dimensions, including education, work experience, learning ability and training; career success contents three dimensions, including perceived internal competitiveness of organization, perceived external competitiveness of organization and career satisfaction. The result of empirical analysis indicates that there is a positive correlation between human capital and career success, and human capital is an excellent predictor of career success beyond demographics variables.

B. F. Skinner's contributions to applied behavior analysis

PubMed Central

Morris, Edward K.; Smith, Nathaniel G.; Altus, Deborah E.

2005-01-01

Our paper reviews and analyzes B. F. Skinner's contributions to applied behavior analysis in order to assess his role as the field's originator and founder. We found, first, that his contributions fall into five categorizes: the style and content of his science, his interpretations of typical and atypical human behavior, the implications he drew from his science for application, his descriptions of possible applications, and his own applications to nonhuman and human behavior. Second, we found that he explicitly or implicitly addressed all seven dimensions of applied behavior analysis. These contributions and the dimensions notwithstanding, he neither incorporated the field's scientific (e.g., analytic) and social dimensions (e.g., applied) into any program of published research such that he was its originator, nor did he systematically integrate, advance, and promote the dimensions so to have been its founder. As the founder of behavior analysis, however, he was the father of applied behavior analysis. PMID:22478444

The Weighted Burgers Vector: a new quantity for constraining dislocation densities and types using electron backscatter diffraction on 2D sections through crystalline materials.

PubMed

Wheeler, J; Mariani, E; Piazolo, S; Prior, D J; Trimby, P; Drury, M R

2009-03-01

The Weighted Burgers Vector (WBV) is defined here as the sum, over all types of dislocations, of [(density of intersections of dislocation lines with a map) x (Burgers vector)]. Here we show that it can be calculated, for any crystal system, solely from orientation gradients in a map view, unlike the full dislocation density tensor, which requires gradients in the third dimension. No assumption is made about gradients in the third dimension and they may be non-zero. The only assumption involved is that elastic strains are small so the lattice distortion is entirely due to dislocations. Orientation gradients can be estimated from gridded orientation measurements obtained by EBSD mapping, so the WBV can be calculated as a vector field on an EBSD map. The magnitude of the WBV gives a lower bound on the magnitude of the dislocation density tensor when that magnitude is defined in a coordinate invariant way. The direction of the WBV can constrain the types of Burgers vectors of geometrically necessary dislocations present in the microstructure, most clearly when it is broken down in terms of lattice vectors. The WBV has three advantages over other measures of local lattice distortion: it is a vector and hence carries more information than a scalar quantity, it has an explicit mathematical link to the individual Burgers vectors of dislocations and, since it is derived via tensor calculus, it is not dependent on the map coordinate system. If a sub-grain wall is included in the WBV calculation, the magnitude of the WBV becomes dependent on the step size but its direction still carries information on the Burgers vectors in the wall. The net Burgers vector content of dislocations intersecting an area of a map can be simply calculated by an integration round the edge of that area, a method which is fast and complements point-by-point WBV calculations.

Think Locally, Act Globally! Linking Local and Global Communities through Democracy and Environment. Hands-On! Developing Active Learning Modules on the Human Dimensions of Global Change.

ERIC Educational Resources Information Center

Dowler, Lorraine

Designed so that it can be adapted to a wide range of student abilities and institutional settings, this learning module on the human dimensions of global change seeks to: actively engage students in problem solving, challenge them to think critically, invite them to participate in the process of scientific inquiry, and involve them in cooperative…

[The linear dimensions of human body measurements of Chinese male pilots in standing posture].

PubMed

Guo, Xiao-chao; Liu, Bao-shan; Xiao, Hui; Wang, Zhi-jie; Li, Rong; Guo, Hui

2003-02-01

To provide the latest anthropometric data of Chinese male pilots on a large scale. 94 linear dimensions of human body measurements were defined, of which there are 42 fundamental items and 52 recommended items. The computer databanks were programmed, in which the subprograms were preset for data checking such as extreme value examination, logical judgement for data relationship, and measuring-remeasuring difference test. All workers were well trained before pilot measurements. 1739 male pilots from China Air Force was measured for the 42 fundamental items, and of which 904 pilots were measured for the 52 recommended items. Mean, standard deviation, the maximum value, the minimal value, and the 5th, 50th, 95th percentile data of all the 94 items were given. The quality of the data was stable and reliable. All data of the 94 linear dimensions of human body measurements were valid and reliable with high precision.

Spatial distribution of block falls using volumetric GIS-decision-tree models

NASA Astrophysics Data System (ADS)

Abdallah, C.

2010-10-01

Block falls are considered a significant aspect of surficial instability contributing to losses in land and socio-economic aspects through their damaging effects to natural and human environments. This paper predicts and maps the geographic distribution and volumes of block falls in central Lebanon using remote sensing, geographic information systems (GIS) and decision-tree modeling (un-pruned and pruned trees). Eleven terrain parameters (lithology, proximity to fault line, karst type, soil type, distance to drainage line, elevation, slope gradient, slope aspect, slope curvature, land cover/use, and proximity to roads) were generated to statistically explain the occurrence of block falls. The latter were discriminated using SPOT4 satellite imageries, and their dimensions were determined during field surveys. The un-pruned tree model based on all considered parameters explained 86% of the variability in field block fall measurements. Once pruned, it classifies 50% in block falls' volumes by selecting just four parameters (lithology, slope gradient, soil type, and land cover/use). Both tree models (un-pruned and pruned) were converted to quantitative 1:50,000 block falls' maps with different classes; starting from Nil (no block falls) to more than 4000 m 3. These maps are fairly matching with coincidence value equal to 45%; however, both can be used to prioritize the choice of specific zones for further measurement and modeling, as well as for land-use management. The proposed tree models are relatively simple, and may also be applied to other areas (i.e. the choice of un-pruned or pruned model is related to the availability of terrain parameters in a given area).

Recurrence quantification analysis applied to spatiotemporal pattern analysis in high-density mapping of human atrial fibrillation.

PubMed

Zeemering, Stef; Bonizzi, Pietro; Maesen, Bart; Peeters, Ralf; Schotten, Ulrich

2015-01-01

Spatiotemporal complexity of atrial fibrillation (AF) patterns is often quantified by annotated intracardiac contact mapping. We introduce a new approach that applies recurrence plot (RP) construction followed by recurrence quantification analysis (RQA) to epicardial atrial electrograms, recorded with a high-density grid of electrodes. In 32 patients with no history of AF (aAF, n=11), paroxysmal AF (PAF, n=12) and persistent AF (persAF, n=9), RPs were constructed using a phase space electrogram embedding dimension equal to the estimated AF cycle length. Spatial information was incorporated by 1) averaging the recurrence over all electrodes, and 2) by applying principal component analysis (PCA) to the matrix of embedded electrograms and selecting the first principal component as a representation of spatial diversity. Standard RQA parameters were computed on the constructed RPs and correlated to the number of fibrillation waves per AF cycle (NW). Averaged RP RQA parameters showed no correlation with NW. Correlations improved when applying PCA, with maximum correlation achieved between RP threshold and NW (RR1%, r=0.68, p <; 0.001) and RP determinism (DET, r=-0.64, p <; 0.001). All studied RQA parameters based on the PCA RP were able to discriminate between persAF and aAF/PAF (DET persAF 0.40 ± 0.11 vs. 0.59 ± 0.14/0.62 ± 0.16, p <; 0.01). RP construction and RQA combined with PCA provide a quick and reliable tool to visualize dynamical behaviour and to assess the complexity of contact mapping patterns in AF.

Regional gene mapping using mixed radiation hybrids and reverse chromosome painting.

PubMed

Lin, J Y; Bedford, J S

1997-11-01

We describe a new approach for low-resolution physical mapping using pooled DNA probe from mixed (non-clonal) populations of human-CHO cell hybrids and reverse chromosome painting. This mapping method is based on a process in which the human chromosome fragments bearing a complementing gene were selectively retained in a large non-clonal population of CHO-human hybrid cells during a series of 12- to 15-Gy gamma irradiations each followed by continuous growth selection. The location of the gene could then be identified by reverse chromosome painting on normal human metaphase spreads using biotinylated DNA from this population of "enriched" hybrid cells. We tested the validity of this method by correctly mapping the complementing human HPRT gene, whose location is well established. We then demonstrated the method's usefulness by mapping the chromosome location of a human gene which complemented the defect responsible for the hypersensitivity to ionizing radiation in CHO irs-20 cells. This method represents an efficient alternative to conventional concordance analysis in somatic cell hybrids where detailed chromosome analysis of numerous hybrid clones is necessary. Using this approach, it is possible to localize a gene for which there is no prior sequence or linkage information to a subchromosomal region, thus facilitating association with known mapping landmarks (e.g. RFLP, YAC or STS contigs) for higher-resolution mapping.

Mapping the human genome

DOE Office of Scientific and Technical Information (OSTI.GOV)

Annas, G.C.; Elias, S.

1992-01-01

This article is a review of the book Mapping the Human Genome: Using Law and Ethics as Guides, edited by George C. Annas and Sherman Elias. The book is a collection of essays on the subject of using ethics and laws as guides to justify human gene mapping. It addresses specific issues such problems related to eugenics, patents, insurance as well as broad issues such as the societal definitions of normality.

Optimizing the sensory characteristics and acceptance of canned cat food: use of a human taste panel.

PubMed

Pickering, G J

2009-02-01

A methodology based on descriptive analysis techniques used in the evaluation of human food has been successfully refined to allow for a human taste panel to profile the flavour and texture of a range of cat food products (CFP) and their component parts. Included in this method is the development of evaluation protocols for homogeneous products and for binary samples containing both meat chunk (MC) and gravy/gel (GG) constituents. Using these techniques, 18 flavour attributes (sweet, sour/acid, tuna, herbal, spicy, soy, salty, cereal, caramel, chicken, methionine, vegetable, offaly, meaty, burnt flavour, prawn, rancid and bitter) and four texture dimensions (hardness, chewiness, grittiness and viscosity) were generated to describe the sensations elicited by 13 commercial pet food samples. These samples differed in intensity for 16 of the 18 flavour attributes, which allows for individual CFP flavour profiles to be developed. Principal components analysis (PCA) could successfully discriminate between samples within the PCA space and also reveal some groupings amongst them. While many flavour attributes were weakly correlated, a large number (describing both taste and retro-nasal aroma qualities) were required to adequately differentiate between samples, suggesting considerable complexity in the products assessed. For both MC and GG, differences between samples for each of the texture dimensions were also found. For MC, grittiness appears to be the most discriminating textural attribute, while for GG viscosity discriminates well between samples. Meat chunks and gravy/gels differed significantly from each other in both flavour and texture. Cat food products differed in their liking ratings, although no differences were found between homogeneous, MC and GG samples, and eight flavour attributes were correlated with overall liking scores. It is now necessary to determine the usefulness and limits of sensory data gathered from human panels in describing and predicting food acceptance and preference behaviours in cats. For instance, while the sense of taste in cats appears generally similar to that of other mammals, they lack a sweet taste receptor (Li et al., 2006), which may limit the applicability of sweetness ratings obtained from humans. Modification of existing techniques used with human food research, such as external preference mapping (Naes and Risvik, 1996) may be useful. Ultimately, this may facilitate more economical and efficient methods for optimizing cat food flavour and texture and predicting the effects of composition and processing changes on cat feeding behaviour. This will require collaboration between pet food manufacturers and nutritionists, animal behaviourists and human sensory scientists. The results of this preliminary study should assist in this process.

Culture, morality and individual differences: comparability and incomparability across species.

PubMed

Saucier, Gerard

2018-04-19

Major routes to identifying individual differences (in diverse species) include studies of behaviour patterns as represented in language and neurophysiology. But results from these approaches appear not to converge on some major dimensions. Identifying dimensions of human variation least applicable to non-human species may help to partition human-specific individual differences of recent evolutionary origin from those shared across species. Human culture includes learned, enforced social-norm systems that are symbolically reinforced and referenced in displays signalling adherence. At a key juncture in human evolution bullying aggression and deception-based cheating apparently became censured in the language of a moral community, enabling mutual observation coordinated in gossip, associated with external sanctions. That still-conserved cultural paradigm moralistically regulates selfish advantage-taking, with shared semantics and explicit rules. Ethics and moral codes remain critical and universal components of human culture and have a stronger imprint in language than most aspects of the currently popular Big-Five taxonomy, a model that sets out five major lines of individual-differences variation in human personality. In other species (e.g. chimpanzees), human observers might see apparent individual differences in morality-relevant traits, but not because the animals have human-analogue sanctioning systems. Removing the moral dimension of personality and other human-specific manifestations (e.g. religion) may aid in identifying those other bases of individual differences more ubiquitous across species.This article is part of the theme issue 'Diverse perspectives on diversity: multi-disciplinary approaches to taxonomies of individual differences'. © 2018 The Author(s).

The Human Genome Initiative: First Steps.

ERIC Educational Resources Information Center

Newman, Alan R.

1990-01-01

Described is the basic biology involved in mapping chromosomes as presented at a symposium at a recent meeting of the American Chemical Association which focused on the Human Genome Initiative. Different types of gene maps and techniques used to produce gene maps are discussed. (CW)

Mapping soil salinity and a fresh-water intrusion in three-dimensions using a quasi-3d joint-inversion of DUALEM-421S and EM34 data

NASA Astrophysics Data System (ADS)

Zare, Ehsan; Huang, Jingyi; Koganti, Triven; Triantafilis, John

2017-04-01

In order to understand the drivers of topsoil salinization, the distribution and movement of salt in accordance with groundwater need mapping. In this study, we described a method to map the distribution of soil salinity, as measured by the electrical conductivity of a saturated soil-paste extract (ECe), and in 3-dimensions around a water storage reservoir in an irrigated field near Bourke, New South Wales, Australia. A quasi-3d electromagnetic conductivity image (EMCI) or model of the true electrical conductivity (sigma) was developed using 133 apparent electrical conductivity (ECa) measurements collected on a 50 m grid and using various coil arrays of DUALEM-421S and EM34 instruments. For the DUALEM-421S we considered ECa in horizontal coplanar (i.e., 1 mPcon, 2 mPcon and 4 mPcon) and vertical coplanar (i.e., 1 mHcon, 2 mHcon and 4 mHcon) arrays. For the EM34, three measurements in the horizontal mode (i.e., EM34-10H, EM34-20H and EM34-40H) were considered. We estimated σ using a quasi-3d joint-inversion algorithm (EM4Soil). The best correlation (R2 = 0.92) between σ and measured soil ECe was identified when a forward modelling (FS), inversion algorithm (S2) and damping factor (lambda = 0.2) were used and using both DUALEM-421 and EM34 data; but not including the 4 m coil arrays of the DUALEM-421S. A linear regression calibration model was used to predict ECe in 3-dimensions beneath the study field. The predicted ECe was consistent with previous studies and revealed the distribution of ECe and helped to infer a freshwater intrusion from a water storage reservoir at depth and as a function of its proximity to near-surface prior stream channels and buried paleochannels. It was concluded that this method can be applied elsewhere to map the soil salinity and water movement and provide guidance for improved land management.|

Mapping soil salinity and a fresh-water intrusion in three-dimensions using a quasi-3d joint-inversion of DUALEM-421S and EM34 data.

PubMed

Huang, J; Koganti, T; Santos, F A Monteiro; Triantafilis, J

2017-01-15

In order to understand the drivers of topsoil salinization, the distribution and movement of salt in accordance with groundwater need mapping. In this study, we described a method to map the distribution of soil salinity, as measured by the electrical conductivity of a saturated soil-paste extract (EC e ), and in 3-dimensions around a water storage reservoir in an irrigated field near Bourke, New South Wales, Australia. A quasi-3d electromagnetic conductivity image (EMCI) or model of the true electrical conductivity (σ) was developed using 133 apparent electrical conductivity (EC a ) measurements collected on a 50m grid and using various coil arrays of DUALEM-421S and EM34 instruments. For the DUALEM-421S we considered EC a in horizontal coplanar (i.e., 1mPcon, 2mPcon and 4mPcon) and vertical coplanar (i.e., 1mHcon, 2mHcon and 4mHcon) arrays. For the EM34, three measurements in the horizontal mode (i.e., EM34-10H, EM34-20H and EM34-40H) were considered. We estimated σ using a quasi-3d joint-inversion algorithm (EM4Soil). The best correlation (R 2 =0.92) between σ and measured soil EC e was identified when a forward modelling (FS), inversion algorithm (S2) and damping factor (λ=0.2) were used and using both DUALEM-421 and EM34 data; but not including the 4m coil arrays of the DUALEM-421S. A linear regression calibration model was used to predict EC e in 3-dimensions beneath the study field. The predicted EC e was consistent with previous studies and revealed the distribution of EC e and helped to infer a freshwater intrusion from a water storage reservoir at depth and as a function of its proximity to near-surface prior stream channels and buried paleochannels. It was concluded that this method can be applied elsewhere to map the soil salinity and water movement and provide guidance for improved land management. Copyright © 2016 Elsevier B.V. All rights reserved.

Age-dependent changes of the normal human spine during adulthood.

PubMed

Rühli, F J; Müntener, M; Henneberg, M

2005-01-01

The impact of aging on the morphology of the osseous spine is still debated. Clinical studies usually record combined aging effects, as well as age-related degenerative changes. The aim of this study was to determine the impact of (degeneration-independent) aging on the morphology of the osseous human spine during adulthood. Various osseous dimensions of human spinal landmarks at all major vertebral levels have been assessed in macroscopically normal Swiss skeletons (N = 71), with historically known sex and age at death, as well as in larger Central European skeletal samples (N = 277) with anthropologically determined individual age and sex. All measurements were correlated with individual age (or age group) by linear regression and analyzed separately for each sex. Only few osseous spinal dimensions, and only in men, correlate significantly with individual age. Generally, the significant dimensions show an increase in size during adulthood. Similar tendencies, but with significant alterations of spinal measurements in women as well, can be found in the larger samples with anthropologically determined sex and age group. Increase of certain spinal dimensions found in this study may be a reflection of an increase in the robustness of individuals with age. Because of the absence of a significant secular alteration of stature within the well-recorded sample, we exclude secular change in body dimensions as a major bias. Copyright 2005 Wiley Periodicals, Inc

Concept Mapping in the Humanities to Facilitate Reflection: Externalizing the Relationship between Public and Personal Learning

ERIC Educational Resources Information Center

Kandiko, Camille; Hay, David; Weller, Saranne

2013-01-01

This article discusses how mapping techniques were used in university teaching in a humanities subject. The use of concept mapping was expanded as a pedagogical tool, with a focus on reflective learning processes. Data were collected through a longitudinal study of concept mapping in a university-level Classics course. This was used to explore how…

Fracturing ranked surfaces

NASA Astrophysics Data System (ADS)

Schrenk, K. J.; Araújo, N. A. M.; Andrade, J. S., Jr.; Herrmann, H. J.

2012-04-01

Discretized landscapes can be mapped onto ranked surfaces, where every element (site or bond) has a unique rank associated with its corresponding relative height. By sequentially allocating these elements according to their ranks and systematically preventing the occupation of bridges, namely elements that, if occupied, would provide global connectivity, we disclose that bridges hide a new tricritical point at an occupation fraction p = pc, where pc is the percolation threshold of random percolation. For any value of p in the interval pc < p <= 1, our results show that the set of bridges has a fractal dimension dBB ~ 1.22 in two dimensions. In the limit p --> 1, a self-similar fracture is revealed as a singly connected line that divides the system in two domains. We then unveil how several seemingly unrelated physical models tumble into the same universality class and also present results for higher dimensions.

Instantons in Lifshitz field theories

NASA Astrophysics Data System (ADS)

Fujimori, Toshiaki; Nitta, Muneto

2015-10-01

BPS instantons are discussed in Lifshitz-type anisotropic field theories. We consider generalizations of the sigma model/Yang-Mills instantons in renormalizable higher dimensional models with the classical Lifshitz scaling invariance. In each model, BPS instanton equation takes the form of the gradient flow equations for "the superpotential" defining "the detailed balance condition". The anisotropic Weyl rescaling and the coset space dimensional reduction are used to map rotationally symmetric instantons to vortices in two-dimensional anisotropic systems on the hyperbolic plane. As examples, we study anisotropic BPS baby Skyrmion 1+1 dimensions and BPS Skyrmion in 2+1 dimensions, for which we take Kähler 1-form and the Wess-Zumiono-Witten term as the superpotentials, respectively, and an anisotropic generalized Yang-Mills instanton in 4 + 1 dimensions, for which we take the Chern-Simons term as the superpotential.

Organizing symmetry-protected topological phases by layering and symmetry reduction: A minimalist perspective

NASA Astrophysics Data System (ADS)

Xiong, Charles Zhaoxi; Alexandradinata, A.

2018-03-01

It is demonstrated that fermionic/bosonic symmetry-protected topological (SPT) phases across different dimensions and symmetry classes can be organized using geometric constructions that increase dimensions and symmetry-reduction maps that change symmetry groups. Specifically, it is shown that the interacting classifications of SPT phases with and without glide symmetry fit into a short exact sequence, so that the classification with glide is constrained to be a direct sum of cyclic groups of order 2 or 4. Applied to fermionic SPT phases in the Wigner-Dyson class AII, this implies that the complete interacting classification in the presence of glide is Z4⊕Z2⊕Z2 in three dimensions. In particular, the hourglass-fermion phase recently realized in the band insulator KHgSb must be robust to interactions. Generalizations to spatiotemporal glide symmetries are discussed.

Hemispherical map for the human brain cortex

NASA Astrophysics Data System (ADS)

Tosun, Duygu; Prince, Jerry L.

2001-07-01

Understanding the function of the human brain cortex is a primary goal in human brain mapping. Methods to unfold and flatten the cortical surface for visualization and measurement have been described in previous literature; but comparison across multiple subjects is still difficult because of the lack of a standard mapping technique. We describe a new approach that maps each hemisphere of the cortex to a portion of a sphere in a standard way, making comparison of anatomy and function across different subjects possible. Starting with a three-dimensional magnetic resonance image of the brain, the cortex is segmented and represented as a triangle mesh. Defining a cut around the corpus collosum identifies the left and right hemispheres. Together, the two hemispheres are mapped to the complex plane using a conformal mapping technique. A Mobius transformation, which is conformal, is used to transform the points on the complex plane so that a projective transformation maps each brain hemisphere onto a spherical segment comprising a sphere with a cap removed. We determined the best size of the spherical cap by minimizing the relative area distortion between hemispherical maps and original cortical surfaces. The relative area distortion between the hemispherical maps and the original cortical surfaces for fifteen human brains is analyzed.

Integrating Social Science into the Long-Term Ecological Research (LTER) Network: Social Dimensions of Ecological Change and Ecological Dimensions of Social Change

Treesearch

Charles L. Redman; J. Morgan Grove; Lauren H. Kuby; Lauren H. Kuby

2004-01-01

The integration of the social sciences into long-term ecological research is an urgent priority. To address this need, a group of social, earth, and life scientists associated with the National Science Foundation's (NSF) Long-Term Ecological Research (LTER) Network have articulated a conceptual framework for understanding the human dimensions of ecological change...

Crowdsourcing as a Novel Approach to Mapping Ecosystem Services in a Great Lakes Area of Concern

EPA Science Inventory

A successful crowdsourcing application depends on two dimensions – the theory and experimental design that guides data collection and the application of the technology to execute the plan. The USEPA Mid-Continent Ecology Division is working on the creation and implementatio...

Mapping the Classroom Emotional Environment

ERIC Educational Resources Information Center

Harvey, Shane T.; Bimler, David; Evans, Ian M.; Kirkland, John; Pechtel, Pia

2012-01-01

Harvey and Evans (2003) have proposed that teachers' emotional skills, as required in the classroom, can be organized into a five-dimensional model. Further research is necessary to validate this model and evaluate the importance of each dimension of teacher emotion competence for educational practice. Using a statistical method for mapping…

How Do Trait Dimensions Map onto ADHD Symptom Domains?

ERIC Educational Resources Information Center

Martel, Michelle M.; Nigg, Joel T.; von Eye, Alexander

2009-01-01

Theories of Attention-Deficit/Hyperactivity Disorder (ADHD) implicate dysfunctional regulation mechanisms that have been conceptually grouped into "top-down" control and "bottom-up" affective/reactive processes. This dual-process account can be invoked in relation to temperament or personality traits and may clarify how traits relate to ADHD. Two…

30 CFR 779.25 - Cross sections, maps, and plans.

Code of Federal Regulations, 2012 CFR

2012-07-01

... locations of monitoring stations used to gather data for water quality and quantity, fish and wildlife, and... encountered, within the proposed permit or adjacent areas; (7) Location of surface water bodies such as... the proposed permit area; (9) Location and dimensions of existing areas of spoil, waste, and non-coal...

30 CFR 779.25 - Cross sections, maps, and plans.

Code of Federal Regulations, 2010 CFR

2010-07-01

... locations of monitoring stations used to gather data for water quality and quantity, fish and wildlife, and... encountered, within the proposed permit or adjacent areas; (7) Location of surface water bodies such as... the proposed permit area; (9) Location and dimensions of existing areas of spoil, waste, and non-coal...

30 CFR 779.25 - Cross sections, maps, and plans.

Code of Federal Regulations, 2014 CFR

2014-07-01

... locations of monitoring stations used to gather data for water quality and quantity, fish and wildlife, and... encountered, within the proposed permit or adjacent areas; (7) Location of surface water bodies such as... the proposed permit area; (9) Location and dimensions of existing areas of spoil, waste, and non-coal...

30 CFR 779.25 - Cross sections, maps, and plans.

Code of Federal Regulations, 2011 CFR

2011-07-01

... locations of monitoring stations used to gather data for water quality and quantity, fish and wildlife, and... encountered, within the proposed permit or adjacent areas; (7) Location of surface water bodies such as... the proposed permit area; (9) Location and dimensions of existing areas of spoil, waste, and non-coal...

30 CFR 779.25 - Cross sections, maps, and plans.

Code of Federal Regulations, 2013 CFR

2013-07-01

... locations of monitoring stations used to gather data for water quality and quantity, fish and wildlife, and... encountered, within the proposed permit or adjacent areas; (7) Location of surface water bodies such as... the proposed permit area; (9) Location and dimensions of existing areas of spoil, waste, and non-coal...

Developing an Instrument to Assess Higher Education Leadership.

ERIC Educational Resources Information Center

Montez, Joni

An instrument was developed to assess the construct of higher education leadership from discrete innate (possessed) and extrinsic (directed toward others) points of view. Dimensions of the latent construct of higher education leadership were identified, and their content and the relationships between their indicators were "mapped" according to the…

Conceptualizing physical activity parenting practices using expert informed concept mapping analysis

USDA-ARS?s Scientific Manuscript database

Parents are widely recognized as playing a central role in the development of child behaviors such as physical activity. As there is little agreement as to the dimensions of physical activity-related parenting practices that should be measured or how they should be operationalized, this study engage...

The Purebred and the Platypus: Disciplinarity and Site in Mass Communication Research.

ERIC Educational Resources Information Center

Kavoori, Anandam P.; Gurevitch, Michael

1993-01-01

Offers thoughts about some of the problems facing mass communication as a cultural practice by mapping briefly its historical constitutiveness (and the problems therein). Discusses the dimensions of communication research as site. Offers a diagnosis of how to view the avowed "fragmentation" of the field. (SR)

A subjective domestic cat (Felis silvestris catus) temperament assessment results in six independent dimensions.

PubMed

Ha, Daniel; Ha, James

2017-08-01

The study of personality or temperament is well developed in many species, but in domestic cats (Felis silvestris catus) it has lagged behind. We applied one common methodology, subjective surveys, performed by their owners, to investigate the dimensions of cat temperament. To do this, we developed an eighteen question survey covering common behavioral traits of cats, and had the evaluators rank their cat on a seven point Likert scale for trait. The responses were analyzed with factor analysis, and resulted in six significant dimensions of temperament across the 251 surveys. The six dimensions, in order of importance, are: Cat Social, Active, Human Nonsocial, Human Aggressive, and Intense. Supplemental questions were also included in all the surveys, and MANOVA analysis of these showed that outdoor usage, feeding style (ad-lib vs. meal fed), living with other cats, sex, duration of ownership, and previous history as a stray all had effects on at least one of the dimensions of cat temperament. Future work is clearly needed to fully validate our model and to further investigate our findings. Copyright © 2017 Elsevier B.V. All rights reserved.

Improving the Curie depth estimation through optimizing the spectral block dimensions of the aeromagnetic data in the Sabalan geothermal field

NASA Astrophysics Data System (ADS)

Akbar, Somaieh; Fathianpour, Nader

2016-12-01

The Curie point depth is of great importance in characterizing geothermal resources. In this study, the Curie iso-depth map was provided using the well-known method of dividing the aeromagnetic dataset into overlapping blocks and analyzing the power spectral density of each block separately. Determining the optimum block dimension is vital in improving the resolution and accuracy of estimating Curie point depth. To investigate the relation between the optimal block size and power spectral density, a forward magnetic modeling was implemented on an artificial prismatic body with specified characteristics. The top, centroid, and bottom depths of the body were estimated by the spectral analysis method for different block dimensions. The result showed that the optimal block size could be considered as the smallest possible block size whose corresponding power spectrum represents an absolute maximum in small wavenumbers. The Curie depth map of the Sabalan geothermal field and its surrounding areas, in the northwestern Iran, was produced using a grid of 37 blocks with different dimensions from 10 × 10 to 50 × 50 km2, which showed at least 50% overlapping with adjacent blocks. The Curie point depth was estimated in the range of 5 to 21 km. The promising areas with the Curie point depths less than 8.5 km are located around Mountain Sabalan encompassing more than 90% of known geothermal resources in the study area. Moreover, the Curie point depth estimated by the improved spectral analysis is in good agreement with the depth calculated from the thermal gradient data measured in one of the exploratory wells in the region.

Evolution of the auditory ossicles in extant hominids: metric variation in African apes and humans.

PubMed

Quam, Rolf M; Coleman, Mark N; Martínez, Ignacio

2014-08-01

The auditory ossicles in primates have proven to be a reliable source of phylogenetic information. Nevertheless, to date, very little data have been published on the metric dimensions of the ear ossicles in African apes and humans. The present study relies on the largest samples of African ape ear ossicles studied to date to address questions of taxonomic differences and the evolutionary transformation of the ossicles in gorillas, chimpanzees and humans. Both African ape taxa show a malleus that is characterized by a long and slender manubrium and relatively short corpus, whereas humans show the opposite constellation of a short and thick manubrium and relatively long corpus. These changes in the manubrium are plausibly linked with changes in the size of the tympanic membrane. The main difference between the incus in African apes and humans seems to be related to changes in the functional length. Compared with chimpanzees, human incudes are larger in nearly all dimensions, except articular facet height, and show a more open angle between the axes. The gorilla incus resembles humans more closely in its metric dimensions, including functional length, perhaps as a result of the dramatically larger body size compared with chimpanzees. The differences between the stapedes of humans and African apes are primarily size-related, with humans being larger in nearly all dimensions. Nevertheless, some distinctions between the African apes were found in the obturator foramen and head height. Although correlations between metric variables in different ossicles were generally lower than those between variables in the same bone, variables of the malleus/incus complex appear to be more strongly correlated than those of the incus/stapes complex, perhaps reflecting the different embryological and evolutionary origins of the ossicles. The middle ear lever ratio for the African apes is similar to other haplorhines, but humans show the lowest lever ratio within primates. Very low levels of sexual dimorphism were found in the ossicles within each taxon, but some relationship with body size and several dimensions of the ear bones was found. Several of the metric distinctions in the incus and stapes imply a slightly different articulation of the ossicular chain within the tympanic cavity in African apes compared with humans. The limited auditory implications of these metric differences in the ossicles are also discussed. Finally, the results of this study suggest that several plesiomorphic features for apes may be retained in the ear bones of the early hominin taxa Australopithecus and Paranthropus as well as in the Neandertals. © 2014 Anatomical Society.

Evolution of the auditory ossicles in extant hominids: metric variation in African apes and humans

PubMed Central

Quam, Rolf M; Coleman, Mark N; Martínez, Ignacio

2014-01-01

The auditory ossicles in primates have proven to be a reliable source of phylogenetic information. Nevertheless, to date, very little data have been published on the metric dimensions of the ear ossicles in African apes and humans. The present study relies on the largest samples of African ape ear ossicles studied to date to address questions of taxonomic differences and the evolutionary transformation of the ossicles in gorillas, chimpanzees and humans. Both African ape taxa show a malleus that is characterized by a long and slender manubrium and relatively short corpus, whereas humans show the opposite constellation of a short and thick manubrium and relatively long corpus. These changes in the manubrium are plausibly linked with changes in the size of the tympanic membrane. The main difference between the incus in African apes and humans seems to be related to changes in the functional length. Compared with chimpanzees, human incudes are larger in nearly all dimensions, except articular facet height, and show a more open angle between the axes. The gorilla incus resembles humans more closely in its metric dimensions, including functional length, perhaps as a result of the dramatically larger body size compared with chimpanzees. The differences between the stapedes of humans and African apes are primarily size-related, with humans being larger in nearly all dimensions. Nevertheless, some distinctions between the African apes were found in the obturator foramen and head height. Although correlations between metric variables in different ossicles were generally lower than those between variables in the same bone, variables of the malleus/incus complex appear to be more strongly correlated than those of the incus/stapes complex, perhaps reflecting the different embryological and evolutionary origins of the ossicles. The middle ear lever ratio for the African apes is similar to other haplorhines, but humans show the lowest lever ratio within primates. Very low levels of sexual dimorphism were found in the ossicles within each taxon, but some relationship with body size and several dimensions of the ear bones was found. Several of the metric distinctions in the incus and stapes imply a slightly different articulation of the ossicular chain within the tympanic cavity in African apes compared with humans. The limited auditory implications of these metric differences in the ossicles are also discussed. Finally, the results of this study suggest that several plesiomorphic features for apes may be retained in the ear bones of the early hominin taxa Australopithecus and Paranthropus as well as in the Neandertals. PMID:24845949

[The metaphysical dimension of animal ethics].

PubMed

Walz, Norbert

2008-01-01

Utilitarian ethics recognises animals as moral objects, but it does not attribute an absolute value to human or non-human individuals. Animal ethics according to Regan defines the non-human individual as an inherent value, but concedes that humans should be given precedence over animals if a situation involves a decision between life and death. Such life and death decisions relate to the fundamental structures of biological nature. To individuals these fundamental structures (the paradox of life and death) will necessarily appear absurd. The metaphysical dimension of animal ethics tries to shed light on the connections between life and death, body and mind that underly ethical discussions and searches for alternatives to the natural organisation of life.

Brain-mapping projects using the common marmoset.

PubMed

Okano, Hideyuki; Mitra, Partha

2015-04-01

Globally, there is an increasing interest in brain-mapping projects, including the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative project in the USA, the Human Brain Project (HBP) in Europe, and the Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) project in Japan. These projects aim to map the structure and function of neuronal circuits to ultimately understand the vast complexity of the human brain. Brain/MINDS is focused on structural and functional mapping of the common marmoset (Callithrix jacchus) brain. This non-human primate has numerous advantages for brain mapping, including a well-developed frontal cortex and a compact brain size, as well as the availability of transgenic technologies. In the present review article, we discuss strategies for structural and functional mapping of the marmoset brain and the relation of the common marmoset to other animals models. Copyright © 2014 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

Surface-based atlases of cerebellar cortex in the human, macaque, and mouse.

PubMed

Van Essen, David C

2002-12-01

This study describes surface reconstructions and associated flat maps that represent the highly convoluted shape of cerebellar cortex in three species: human, macaque, and mouse. The reconstructions were based on high-resolution structural MRI data obtained from other laboratories. The surface areas determined for the fiducial reconstructions are about 600 cm(2) for the human, 60 cm(2) for the macaque, and 0.8 cm(2) for the mouse. As expected from the ribbon-like pattern of cerebellar folding, the cerebellar flat maps are elongated along the axis parallel to the midline. However, the degree of elongation varies markedly across species. The macaque flat map is many times longer than its mean width, whereas the mouse flat map is only slightly elongated and the human map is intermediate in its aspect ratio. These cerebellar atlases, along with associated software for visualization and for mapping experimental data onto the atlas, are freely available to the neuroscience community (see http:/brainmap.wustl.edu).

Surface-based atlases of cerebellar cortex in the human, macaque, and mouse

NASA Technical Reports Server (NTRS)

Van Essen, David C.

2002-01-01

This study describes surface reconstructions and associated flat maps that represent the highly convoluted shape of cerebellar cortex in three species: human, macaque, and mouse. The reconstructions were based on high-resolution structural MRI data obtained from other laboratories. The surface areas determined for the fiducial reconstructions are about 600 cm(2) for the human, 60 cm(2) for the macaque, and 0.8 cm(2) for the mouse. As expected from the ribbon-like pattern of cerebellar folding, the cerebellar flat maps are elongated along the axis parallel to the midline. However, the degree of elongation varies markedly across species. The macaque flat map is many times longer than its mean width, whereas the mouse flat map is only slightly elongated and the human map is intermediate in its aspect ratio. These cerebellar atlases, along with associated software for visualization and for mapping experimental data onto the atlas, are freely available to the neuroscience community (see http:/brainmap.wustl.edu).

Classification of Depressive Disorders in DSM-V: Proposal for a Two-Dimension System

PubMed Central

Klein, Daniel N.

2011-01-01

The number of categories and specifiers for mood disorders has increased with each successive edition of the Diagnostic and Statistical Manual for Mental Disorders (DSM). Many of these categories and specifiers can be viewed as an effort to map the various permutations of severity and chronicity that characterize the depressive disorders. However, this has resulted in a system that is unnecessarily complex and unwieldy, and created problems with artificial distinctions between categories and artifactual comorbidity, and at the same time obscures what may be more fundamental distinctions. A potentially useful and more parsimonious approach to capturing much of the heterogeneity of depressive disorders is to classify the depressive disorders along two dimensions, one reflecting severity and the other chronicity. Considerations in the development of these dimensions are discussed, and a set of examples is presented. Although further research and discussion are needed to determine the optimal form of these dimensions, the next edition of the DSM should consider replacing many of the existing categories and specifiers for depressive disorders with the simpler approach of classifying depressive disorders using the two dimensions of severity and chronicity. PMID:18729608

Re-thinking the classification of autism spectrum disorders

PubMed Central

Lord, Catherine; Jones, Rebecca M.

2012-01-01

Background The nosology of autism spectrum disorders (ASD) is at a critical point in history as the field seeks to better define dimensions of social-communication deficits and restricted/repetitive behaviors on an individual level for both clinical and neurobiological purposes. These different dimensions also suggest an increasing need for quantitative measures that accurately map their differences, independent of developmental factors such as age, language level and IQ. Method Psychometric measures, clinical observation as well as genetic, neurobiological and physiological research from toddlers, children and adults with ASD are reviewed. Results The question of how to conceptualize ASDs along dimensions versus categories is discussed within the nosology of autism and the proposed changes to the DSM-5 and ICD-11. Differences across development are incorporated into the new classification frameworks. Conclusions It is crucial to balance the needs of clinical practice in ASD diagnostic systems, with neurobiologically based theories that address the associations between social-communication and restricted/repetitive dimensions in individuals. Clarifying terminology, improving description of the core features of ASD and other dimensions that interact with them and providing more valid and reliable ways to quantify them, both for research and clinical purposes, will move forward both practice and science. PMID:22486486

Comparative genome map of human and cattle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Solinas-Toldo, S.; Fries, R.; Lengauer, C.

Chromosomal homologies between individual human chromosomes and the bovine karyotype have been established by using a new approach termed Zoo-FISH. Labeled DNA libraries from flow-sorted human chromosomes were used as probes for fluorescence in situ hybridization on cattle chromosomes. All human DNA libraries, except the Y chromosome library, hybridized to one or more cattle chromosomes, identifying and delineating 50 segments of homology, most of them corresponding to the regions of homology as identified by the previous mapping of individual conserved loci. However, Zoo-FISH refines the comparative maps constructed by molecular gene mapping of individual loci by providing information on themore » boundaries of conserved regions in the absence of obvious cytogenetic homologies of human and bovine chromosomes. It allows study of karyotypic evolution and opens new avenues for genomic analysis by facilitating the extrapolation of results from the human genome initiative. 50 refs., 3 figs., 1 tab.« less

The active gene that encodes human High Mobility Group 1 protein (HMG1) contains introns and maps to chromosome 13

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ferrari, S.; Finelli, P.; Rocchi, M.

The human genome contains a large number of sequences related to the cDNA for High Mobility Group 1 protein (HMG1), which so far has hampered the cloning and mapping of the active HMG1 gene. We show that the human HMG1 gene contains introns, while the HMG1-related sequences do not and most likely are retrotransposed pseudogenes. We identified eight YACs from the ICI and CEPH libraries that contain the human HMG1 gene. The HMG1 gene is similar in structure to the previously characterized murine homologue and maps to human chromosome 13 and q12, as determined by in situ hybridization. The mousemore » Hmg1 gene maps to the telomeric region of murine Chromosome 5, which is syntenic to the human 13q12 band. 18 refs., 3 figs.« less

Rapid and long-lasting plasticity of input-output mapping.

PubMed

Yamamoto, Kenji; Hoffman, Donna S; Strick, Peter L

2006-11-01

Skilled use of tools requires us to learn an "input-output map" for the device, i.e., how our movements relate to the actions of the device. We used the paradigm of visuo-motor rotation to examine two questions about the plasticity of input-output maps: 1) does extensive practice on one mapping make it difficult to modify and/or to form a new input-output map and 2) once a map has been modified or a new map has been formed, does this map survive a gap in performance? Humans and monkeys made wrist movements to control the position of a cursor on a computer monitor. Humans practiced the task for approximately 1.5 h; monkeys practiced for 3-9 yr. After this practice, we gradually altered the direction of cursor movement relative to wrist movement while subjects moved either to a single target or to four targets. Subjects were unaware of the change in cursor-movement relationship. Despite their prior practice on the task, the humans and the monkeys quickly adjusted their motor output to compensate for the visuo-motor rotation. Monkeys retained the modified input-output map during a 2-wk gap in motor performance. Humans retained the altered map during a gap of >1 yr. Our results show that sensorimotor performance remains flexible despite considerable practice on a specific task, and even relatively short-term exposure to a new input-output mapping leads to a long-lasting change in motor performance.

A radiation hybrid map of the proximal long arm of human chromosome 11 containing the multiple endocrine neoplasia type 1 (MEN-1) and bcl-1 disease loci.

PubMed Central

Richard, C W; Withers, D A; Meeker, T C; Maurer, S; Evans, G A; Myers, R M; Cox, D R

1991-01-01

We describe a high-resolution radiation hybrid map of the proximal long arm of human chromosome 11 containing the bcl-1 and multiple endocrine neoplasia type 1 (MEN-1) disease gene loci. We used X-ray irradiation and cell fusion to generate a panel of 102 hamster-human somatic cell hybrids containing fragments of human chromosome 11. Sixteen human loci in the 11q12-13 region were mapped by statistical analysis of the cosegregation of markers in these radiation hybrids. The most likely order for these loci is C1NH-OSBP-(CD5/CD20)-PGA-FTH1-COX8-PYGM -SEA-KRN1-(MTC/P11EH/HSTF1/INT2)-GST3- PPP1A. Our localization of the human protooncogene SEA between PYGM and INT2, two markers that flank MEN-1, suggests SEA as a potential candidate for the MEN-1 locus. We map two mitogenic fibroblast growth factor genes, HSTF1 and INT2, close to bcl-1, a mapping that is consistent with previously published data. Our map places the human leukocyte antigen genes CD5 and CD20 far from the bcl-1 locus, indicating that CD5 and CD20 expression is unlikely to be altered by bcl-1 rearrangements. PPP1A, which has been postulated as a MEN-1 candidate tumor suppressor gene, and GST3, a gene transcriptionally active in many human cancers, both map distal to the bcl-1 translocation cluster and the region containing MEN-1, and therefore are unlikely to be directly involved in bcl-1 or MEN-1. PMID:1684084

A radiation hybrid map of the proximal long arm of human chromosome 11 containing the multiple endocrine neoplasia type 1 (MEN-1) and bcl-1 disease loci.

PubMed

Richard, C W; Withers, D A; Meeker, T C; Maurer, S; Evans, G A; Myers, R M; Cox, D R

1991-12-01

We describe a high-resolution radiation hybrid map of the proximal long arm of human chromosome 11 containing the bcl-1 and multiple endocrine neoplasia type 1 (MEN-1) disease gene loci. We used X-ray irradiation and cell fusion to generate a panel of 102 hamster-human somatic cell hybrids containing fragments of human chromosome 11. Sixteen human loci in the 11q12-13 region were mapped by statistical analysis of the cosegregation of markers in these radiation hybrids. The most likely order for these loci is C1NH-OSBP-(CD5/CD20)-PGA-FTH1-COX8-PYGM -SEA-KRN1-(MTC/P11EH/HSTF1/INT2)-GST3- PPP1A. Our localization of the human protooncogene SEA between PYGM and INT2, two markers that flank MEN-1, suggests SEA as a potential candidate for the MEN-1 locus. We map two mitogenic fibroblast growth factor genes, HSTF1 and INT2, close to bcl-1, a mapping that is consistent with previously published data. Our map places the human leukocyte antigen genes CD5 and CD20 far from the bcl-1 locus, indicating that CD5 and CD20 expression is unlikely to be altered by bcl-1 rearrangements. PPP1A, which has been postulated as a MEN-1 candidate tumor suppressor gene, and GST3, a gene transcriptionally active in many human cancers, both map distal to the bcl-1 translocation cluster and the region containing MEN-1, and therefore are unlikely to be directly involved in bcl-1 or MEN-1.

Dynamic Quantitative Trait Locus Analysis of Plant Phenomic Data.

PubMed

Li, Zitong; Sillanpää, Mikko J

2015-12-01

Advanced platforms have recently become available for automatic and systematic quantification of plant growth and development. These new techniques can efficiently produce multiple measurements of phenotypes over time, and introduce time as an extra dimension to quantitative trait locus (QTL) studies. Functional mapping utilizes a class of statistical models for identifying QTLs associated with the growth characteristics of interest. A major benefit of functional mapping is that it integrates information over multiple timepoints, and therefore could increase the statistical power for QTL detection. We review the current development of computationally efficient functional mapping methods which provide invaluable tools for analyzing large-scale timecourse data that are readily available in our post-genome era. Copyright © 2015 Elsevier Ltd. All rights reserved.

New approach to study mobility in the vicinity of dynamical arrest; exact application to a kinetically constrained model

NASA Astrophysics Data System (ADS)

DeGregorio, P.; Lawlor, A.; Dawson, K. A.

2006-04-01

We introduce a new method to describe systems in the vicinity of dynamical arrest. This involves a map that transforms mobile systems at one length scale to mobile systems at a longer length. This map is capable of capturing the singular behavior accrued across very large length scales, and provides a direct route to the dynamical correlation length and other related quantities. The ideas are immediately applicable in two spatial dimensions, and have been applied to a modified Kob-Andersen type model. For such systems the map may be derived in an exact form, and readily solved numerically. We obtain the asymptotic behavior across the whole physical domain of interest in dynamical arrest.

The Weyl law for contractive maps

NASA Astrophysics Data System (ADS)

Spina, Maria E.; Rivas, Alejandro M. F.; Carlo, Gabriel

2013-11-01

We find an empirical Weyl law followed by the eigenvalues of contractive maps. An important property is that it is mainly insensitive to the dimension of the corresponding invariant classical set, the strange attractor. The usual explanation for the fractal Weyl law emergence in scattering systems (i.e., having a projective opening) is based on the classical phase space distributions evolved up to the quantum to classical correspondence (Ehrenfest) time. In the contractive case this reasoning fails to describe it. Instead, we conjecture that the support for this behavior is essentially given by the strong non-orthogonality of the eigenvectors of the contractive superoperator. We test the validity of the Weyl law and this conjecture on two paradigmatic systems, the dissipative baker and kicked top maps.

Mycobacterium avium subsp paratuberculosis--incidences in milk and milk products, their isolation, enumeration, characterization, and role in human health.

PubMed

Patel, Ami; Shah, Nihir

2011-12-01

Mycobacterium avium subsp paratuberculosis (MAP), excreted in the feces and milk, is reported to be not easily inactivated by pasteurization and thermal treatments as other bacteria infecting humans and animals do. The D values of all MAP strains tested were considerably higher than those published for other pathogens. Culturing techniques for this organism are labor intensive. Although an increasing amount of scientific evidence suggests that this organism can be responsible for at least some cases of Crohn's disease (CD), there is controversy about MAP being a cause of CD in humans. In general, although some studies have described an association between the presence of MAP and CD, the role of Mycobacterium species and MAP in the etiology of this human disease remains unestablished. Although published reports indicate that it may not be completely inactivated by pasteurization of milk, the effectiveness of increasing the time or temperature in the pasteurization process has not been established and hence any potential benefit to human health cannot be determined. This article summarizes the incidences of MAP in milk and milk products with respect to human health and brief discussion of various serological as well as molecular techniques used for their isolation, enumeration, and characterization. Copyright © 2011. Published by Elsevier B.V.

Weighting the Decisive Operation: Updating Army Leadership Doctrine and Training to Meet the Needs of Our Soldiers and Deliver Decisive Victory

DTIC Science & Technology

2015-02-17

outset of human development. In fact, the cultivation of EI during childhood and early adolescence has far reaching direct and indirect cognitive and...relatively inexpensive and efficient proposal. Early measurement of EI, prior to commissioning, will enable researchers to establish a baseline of...Dimension Working Group, subject: Human Dimension Strategy Update, 7 January 2015. Bullis , Craig and George E. Reed. Assessing Leaders to Establish and

Critical Factors Influencing Decision to Adopt Human Resource Information System (HRIS) in Hospitals

PubMed Central

Alam, Md Golam Rabiul; Masum, Abdul Kadar Muhammad; Beh, Loo-See; Hong, Choong Seon

2016-01-01

The aim of this research is to explore factors influencing the management decisions to adopt human resource information system (HRIS) in the hospital industry of Bangladesh—an emerging developing country. To understand this issue, this paper integrates two prominent adoption theories—Human-Organization-Technology fit (HOT-fit) model and Technology-Organization-Environment (TOE) framework. Thirteen factors under four dimensions were investigated to explore their influence on HRIS adoption decisions in hospitals. Employing non-probability sampling method, a total of 550 copies of structured questionnaires were distributed among HR executives of 92 private hospitals in Bangladesh. Among the respondents, usable questionnaires were 383 that suggesting a valid response rate of 69.63%. We classify the sample into 3 core groups based on the HRIS initial implementation, namely adopters, prospectors, and laggards. The obtained results specify 5 most critical factors i.e. IT infrastructure, top management support, IT capabilities of staff, perceived cost, and competitive pressure. Moreover, the most significant dimension is technological dimension followed by organisational, human, and environmental among the proposed 4 dimensions. Lastly, the study found existence of significant differences in all factors across different adopting groups. The study results also expose constructive proposals to researchers, hospitals, and the government to enhance the likelihood of adopting HRIS. The present study has important implications in understanding HRIS implementation in developing countries. PMID:27494334

Critical Factors Influencing Decision to Adopt Human Resource Information System (HRIS) in Hospitals.

PubMed

Alam, Md Golam Rabiul; Masum, Abdul Kadar Muhammad; Beh, Loo-See; Hong, Choong Seon

2016-01-01

The aim of this research is to explore factors influencing the management decisions to adopt human resource information system (HRIS) in the hospital industry of Bangladesh-an emerging developing country. To understand this issue, this paper integrates two prominent adoption theories-Human-Organization-Technology fit (HOT-fit) model and Technology-Organization-Environment (TOE) framework. Thirteen factors under four dimensions were investigated to explore their influence on HRIS adoption decisions in hospitals. Employing non-probability sampling method, a total of 550 copies of structured questionnaires were distributed among HR executives of 92 private hospitals in Bangladesh. Among the respondents, usable questionnaires were 383 that suggesting a valid response rate of 69.63%. We classify the sample into 3 core groups based on the HRIS initial implementation, namely adopters, prospectors, and laggards. The obtained results specify 5 most critical factors i.e. IT infrastructure, top management support, IT capabilities of staff, perceived cost, and competitive pressure. Moreover, the most significant dimension is technological dimension followed by organisational, human, and environmental among the proposed 4 dimensions. Lastly, the study found existence of significant differences in all factors across different adopting groups. The study results also expose constructive proposals to researchers, hospitals, and the government to enhance the likelihood of adopting HRIS. The present study has important implications in understanding HRIS implementation in developing countries.

Earthquake impact on settlements: the role of urban and structural morphology

NASA Astrophysics Data System (ADS)

Bostenaru Dan, M.; Armas, I.

2015-10-01

This study is aimed to create an alternative to the classical GIS representation of the impact of earthquake hazards on urban areas. To accomplish this, the traditional map was revised, so that it can cope with contemporary innovative ways of planning, namely strategic planning. As in the theory of fractals, the building dimension and the urban neighbourhood dimension are addressed as different geographic scales between which lessons for decisions can be learned through regression. The interaction between the two scales is useful when looking for alternatives, for the completion of a GIS analysis, and in choosing the landmarks, which, in the case of hazards, become strategic elements in strategic planning. A methodology to innovate mapping as a digital means for analysing and visualising the impact of hazards is proposed. This method relies on concepts from various geography, urban planning, structural engineering and architecture approaches related to disaster management. The method has been tested at the building scale for the N-S Boulevard in Bucharest, Romania, called Magheru. At the urban scale, an incident database has been created, in which the case study for the building level can be mapped. The paper presented is part of a larger research work, which addresses decision making using the framework shown here. The main value of the paper is in proposing a conceptual framework to deconstruct the map for digital earthquake disaster impact analysis and representation. The originality of the concept consists in the representation of elements at different scales considered to be of different levels of importance in the urban tissue, according to the analysis to be performed on them.

How predictable is the behaviour of torrential processes: two case studies of the summer 2012

NASA Astrophysics Data System (ADS)

Huebl, Johannes; Eisl, Julia; Janu, Stefan; Hanspeter, Pussnig

2013-04-01

Debris flow hazards play an important role in the Austrian Alps since many villages are located on alluvial fans. Most of the mitigation Measures as well as Hazard Zone Maps are designed by engineers of previous generations, who know quite a lot about the torrential behaviour from their experience. But speaking in terms of recurrence intervals of 100 years or even more, human memory is restricted. On the other hand numerical modelling is a fast growing task in dealing with natural hazards. Scenarios of torrential hazards can be defined and accordant deposition pattern, flow depths and velocities are calculated. But of course, errors in the input data must lead to fatal errors in the results, consequently threaten human life in possible affected areas. Thus the need for data collection of exceptional events can help to reproduce the reality in a quite high grade, indeed, but unexpected events are still an issue and pose a challenge to engineers. In summer 2012 two debris flow events occurred in Austria with quite different behaviours, from triggering mechanism and flow behaviour through to deposition: Thunderstorms or long lasting rainfall, slope failures with subsequent channel blockage and dike breaching or linear erosion, one or more debris flows, one huge debris flow surge or a series of debris flow surges, sediments without clay or cohesive material, near channel deposition or outspread deposits. Both debris flows have been unexpected in their dimension, although mitigation measures and hazard maps exist. Both events were documented accurately, first to try to understand the torrential process occurred, second to identify the most fitting mitigation measures, ranging from permanent structures to temporary warning systems.

Dissociable relations between amygdala subregional networks and psychopathy trait dimensions in conduct-disordered juvenile offenders.

PubMed

Aghajani, Moji; Colins, Olivier F; Klapwijk, Eduard T; Veer, Ilya M; Andershed, Henrik; Popma, Arne; van der Wee, Nic J; Vermeiren, Robert R J M

2016-11-01

Psychopathy is a serious psychiatric phenomenon characterized by a pathological constellation of affective (e.g., callous, unemotional), interpersonal (e.g., manipulative, egocentric), and behavioral (e.g., impulsive, irresponsible) personality traits. Though amygdala subregional defects are suggested in psychopathy, the functionality and connectivity of different amygdala subnuclei is typically disregarded in neurocircuit-level analyses of psychopathic personality. Hence, little is known of how amygdala subregional networks may contribute to psychopathy and its underlying trait assemblies in severely antisocial people. We addressed this important issue by uniquely examining the intrinsic functional connectivity of basolateral (BLA) and centromedial (CMA) amygdala networks in relation to affective, interpersonal, and behavioral traits of psychopathy, in conduct-disordered juveniles with a history of serious delinquency (N = 50, mean age = 16.83 ± 1.32). As predicted, amygdalar connectivity profiles exhibited dissociable relations with different traits of psychopathy. Interpersonal psychopathic traits not only related to increased connectivity of BLA and CMA with a corticostriatal network formation accommodating reward processing, but also predicted stronger CMA connectivity with a network of cortical midline structures supporting sociocognitive processes. In contrast, affective psychopathic traits related to diminished CMA connectivity with a frontolimbic network serving salience processing and affective responding. Finally, behavioral psychopathic traits related to heightened BLA connectivity with a frontoparietal cluster implicated in regulatory executive functioning. We suggest that these trait-specific shifts in amygdalar connectivity could be particularly relevant to the psychopathic phenotype, as they may fuel a self-centered, emotionally cold, and behaviorally disinhibited profile. Hum Brain Mapp 37:4017-4033, 2016. © 2016 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc. © 2016 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.

Human factors considerations in the design and evaluation of moving map displays of ownership on the airport surface

DOT National Transportation Integrated Search

2004-09-01

The Federal Aviation Administration (FAA) has requested human factors guidance to support the new moving map Technical Standard Order (TSO)-C165, Electronic Map Display Equipment for Graphical Depiction of Aircraft Position. This document was develop...

Dimensions of landscape preferences from pairwise comparisons

Treesearch

F. González Bernaldez; F. Parra

1979-01-01

Analysis of landscape preferences allows the detection of major dimensions as:(1) the opposition between "natural and humanized", (comprising features like vegetation cover, cultivation, pattern of landscape elements, artifacts, excavations, etc.); (2) polarity "precision/ambiguity" (involving opposition between: predominance of straight, vertical...

Mass fractal dimension and spectral dimension to characterize different horizons in La Herreria (Sierra de Guadarrama, Spain)

NASA Astrophysics Data System (ADS)

Inclan, Rosa Maria

2016-04-01

Knowledge on three dimensional soil pore architecture is important to improve our understanding of the factors that control a number of critical soil processes as it controls biological, chemical and physical processes at various scales. Computed Tomography (CT) images provide increasingly reliable information about the geometry of pores and solids in soils at very small scale with the benefit that is a non-invasive technique. Fractal formalism has revealed as a useful tool in these cases where highly complex and heterogeneous meda are studied. One of these quantifications is mass dimension (Dm) and spectral dimension (d) applied to describe the water and gas diffusion coefficients in soils (Tarquis et al., 2012). In this work, intact soil samples were collected from the first three horizons of La Herreria soil. This station is located in the lowland mountain area of Sierra de Guadarrama (Santolaria et al., 2015) and it represents a highly degraded type of site as a result of the livestock keeping. The 3D images, of 45.1 micro-m resolution (256x256x256 voxels), were obtained and then binarized following the singularity-CA method (Martín-Sotoca et al. 2016). Based on these images Dm and d were estimated. The results showed an statistical difference in porosity, Dm and d for each horizon. This fact has a direct implication in diffusion parameters for a pore network modeling based on both fractal dimensions. These soil parameters will constitute a basis for site characterization for further studies regarding soil degradation; determining the interaction between soil, plant and atmosphere with respect to human induced activities as well as the basis for several nitrogen and carbon cycles modeling. References Martin Sotoca; J.J. Ana M. Tarquis, Antonio Saa Requejo, and Juan B. Grau (2016). Pore detection in Computed Tomography (CT) soil 3D images using singularity map analysis. Geophysical Research Abstracts, 18, EGU2016-829. Santolaria-Canales, Edmundo and the GuMNet Consortium Team (2015). GuMNet - Guadarrama Monitoring Network. Installation and set up of a high altitude monitoring network, north of Madrid. Spain. Geophysical Research Abstracts, 17, EGU2015-13989-2. Tarquis, A. M., Sanchez, M. E., Antón, J. M., Jimenez, J., Saa-Requejo, A., Andina, D., & Crawford, J. W. (2012). Variation in spectral and mass dimension on three-dimensional soil image processing. Soil Science, 177(2), 88-97. Web: http://www.ucm.es/gumnet/

Four-dimensional maps of the human somatosensory system

PubMed Central

Avanzini, Pietro; Abdollahi, Rouhollah O.; Sartori, Ivana; Caruana, Fausto; Pelliccia, Veronica; Casaceli, Giuseppe; Mai, Roberto; Lo Russo, Giorgio; Rizzolatti, Giacomo; Orban, Guy A.

2016-01-01

A fine-grained description of the spatiotemporal dynamics of human brain activity is a major goal of neuroscientific research. Limitations in spatial and temporal resolution of available noninvasive recording and imaging techniques have hindered so far the acquisition of precise, comprehensive four-dimensional maps of human neural activity. The present study combines anatomical and functional data from intracerebral recordings of nearly 100 patients, to generate highly resolved four-dimensional maps of human cortical processing of nonpainful somatosensory stimuli. These maps indicate that the human somatosensory system devoted to the hand encompasses a widespread network covering more than 10% of the cortical surface of both hemispheres. This network includes phasic components, centered on primary somatosensory cortex and neighboring motor, premotor, and inferior parietal regions, and tonic components, centered on opercular and insular areas, and involving human parietal rostroventral area and ventral medial-superior-temporal area. The technique described opens new avenues for investigating the neural basis of all levels of cortical processing in humans. PMID:26976579

Four-dimensional maps of the human somatosensory system.

PubMed

Avanzini, Pietro; Abdollahi, Rouhollah O; Sartori, Ivana; Caruana, Fausto; Pelliccia, Veronica; Casaceli, Giuseppe; Mai, Roberto; Lo Russo, Giorgio; Rizzolatti, Giacomo; Orban, Guy A

2016-03-29

A fine-grained description of the spatiotemporal dynamics of human brain activity is a major goal of neuroscientific research. Limitations in spatial and temporal resolution of available noninvasive recording and imaging techniques have hindered so far the acquisition of precise, comprehensive four-dimensional maps of human neural activity. The present study combines anatomical and functional data from intracerebral recordings of nearly 100 patients, to generate highly resolved four-dimensional maps of human cortical processing of nonpainful somatosensory stimuli. These maps indicate that the human somatosensory system devoted to the hand encompasses a widespread network covering more than 10% of the cortical surface of both hemispheres. This network includes phasic components, centered on primary somatosensory cortex and neighboring motor, premotor, and inferior parietal regions, and tonic components, centered on opercular and insular areas, and involving human parietal rostroventral area and ventral medial-superior-temporal area. The technique described opens new avenues for investigating the neural basis of all levels of cortical processing in humans.

A period-doubling cascade precedes chaos for planar maps.

PubMed

Sander, Evelyn; Yorke, James A

2013-09-01

A period-doubling cascade is often seen in numerical studies of those smooth (one-parameter families of) maps for which as the parameter is varied, the map transitions from one without chaos to one with chaos. Our emphasis in this paper is on establishing the existence of such a cascade for many maps with phase space dimension 2. We use continuation methods to show the following: under certain general assumptions, if at one parameter there are only finitely many periodic orbits, and at another parameter value there is chaos, then between those two parameter values there must be a cascade. We investigate only families that are generic in the sense that all periodic orbit bifurcations are generic. Our method of proof in showing there is one cascade is to show there must be infinitely many cascades. We discuss in detail two-dimensional families like those which arise as a time-2π maps for the Duffing equation and the forced damped pendulum equation.

Mapping alteration minerals at prospect, outcrop and drill core scales using imaging spectrometry

PubMed Central

Kruse, Fred A.; L. Bedell, Richard; Taranik, James V.; Peppin, William A.; Weatherbee, Oliver; Calvin, Wendy M.

2011-01-01

Imaging spectrometer data (also known as ‘hyperspectral imagery’ or HSI) are well established for detailed mineral mapping from airborne and satellite systems. Overhead data, however, have substantial additional potential when used together with ground-based measurements. An imaging spectrometer system was used to acquire airborne measurements and to image in-place outcrops (mine walls) and boxed drill core and rock chips using modified sensor-mounting configurations. Data were acquired at 5 nm nominal spectral resolution in 360 channels from 0.4 to 2.45 μm. Analysis results using standardized hyperspectral methodologies demonstrate rapid extraction of representative mineral spectra and mapping of mineral distributions and abundances in map-plan, with core depth, and on the mine walls. The examples shown highlight the capabilities of these data for mineral mapping. Integration of these approaches promotes improved understanding of relations between geology, alteration and spectral signatures in three dimensions and should lead to improved efficiency of mine development, operations and ultimately effective mine closure. PMID:25937681

Central Limit Theorems for the Shrinking Target Problem

NASA Astrophysics Data System (ADS)

Haydn, Nicolai; Nicol, Matthew; Vaienti, Sandro; Zhang, Licheng

2013-12-01

Suppose B i := B( p, r i ) are nested balls of radius r i about a point p in a dynamical system ( T, X, μ). The question of whether T i x∈ B i infinitely often (i.o.) for μ a.e. x is often called the shrinking target problem. In many dynamical settings it has been shown that if diverges then there is a quantitative rate of entry and for μ a.e. x∈ X. This is a self-norming type of strong law of large numbers. We establish self-norming central limit theorems (CLT) of the form (in distribution) for a variety of hyperbolic and non-uniformly hyperbolic dynamical systems, the normalization constants are . Dynamical systems to which our results apply include smooth expanding maps of the interval, Rychlik type maps, Gibbs-Markov maps, rational maps and, in higher dimensions, piecewise expanding maps. For such central limit theorems the main difficulty is to prove that the non-stationary variance has a limit in probability.

Perceived human rights violation in persons with mental illness: role of education.

PubMed

Vijayalakshmi, Poreddi; Ramachandra; Reddemma, Konduru; Math, Suresh Bada

2013-06-01

People with mental illness are vulnerable to human rights violations and people with illiteracy and mental illness are at a double disadvantage. To determine the role of education in ascertaining human rights needs of people with mental illness. This was a descriptive study carried out among randomly selected (N = 100) recovered psychiatric patients with mental illness in the past based on the Clinical Global Impression-Improvement scale at a tertiary care centre. Data were collected through face-to-face interview using structured needs assessment questionnaire comprising two sections related to family and community domains. Data were analysed and interpreted using descriptive and inferential statistics. Our findings revealed that human rights needs in the physical needs dimension--i.e., access to electricity (χ2 = 5.523, p < .019) and safe drinking water facilities (χ2 = 9.665, p < .022)--were rated higher in illiterates than in literates. The human rights needs in emotional dimension - i.e. feeling separated from their families because of their illness (χ2 = 13.118, p < .004), afraid of family members (χ2 = 13.388, p < .004) and called filthy nicknames (χ2 = 17.759, p < .000) - were rated higher in literates than in illiterates. The human rights needs in the religious needs dimension - i.e. allowed to go to temple, church, mosque etc. (χ2 = 12.000, p < .007) - and in the social needs dimension - i.e. friendliness with family members -were rated higher in illiterates than in literates (χ2 = 9.661, p < .022). Empowering people with mental illness by providing adequate opportunity to pursue education will play an important role in fulfilling the obligation of the United Nations Convention on the Rights of Persons with Disabilities.

The public display of plastinates as a challenge to the integrity of anatomy.

PubMed

Jones, David Gareth

2016-01-01

Anatomy has been thrust into the public domain by the highly successful public displays of dissected and plastinated human bodies. This is anatomy in modern guise, anatomy as perceived by the general public. If this is the case, the message it is giving the public about the nature of anatomy is that it is an impersonal analysis of the human body of value within a medical and health care environment. While this is in part true, and while it reflects important aspects of anatomy's history, it fails to reflect the humanistic strands within an increasing swathe of contemporary anatomy. These are manifested in growing recognition of the centrality of informed consent in the practice of anatomy, awareness of the personal dimensions and relationships of those whose bodies are being dissected, and manifested in thanksgiving ceremonies involving staff and students. The notion that the bodies undergoing dissection can be students' first teachers and/or patients is gaining ground, another indication of the human dimensions of the anatomical enterprise. Exhibitions such as Body Worlds ignore these dimensions within anatomy by dislocating it from its clinical and relational base. The significance of this is that loss of these dimensions leads to a loss of the human face of anatomy by isolating it from the people whose body bequests made this knowledge possible. What is required is greater transparency and openness in the practices of all who deal with the dead human body, trends that owe much to the writings of scholars from within a range of humanities disciplines as they have responded to the public displays of dissected plastinated bodies. Anatomists have much to learn from these debates. © 2015 Wiley Periodicals, Inc.

Single-molecule optical genome mapping of a human HapMap and a colorectal cancer cell line.

PubMed

Teo, Audrey S M; Verzotto, Davide; Yao, Fei; Nagarajan, Niranjan; Hillmer, Axel M

2015-01-01

Next-generation sequencing (NGS) technologies have changed our understanding of the variability of the human genome. However, the identification of genome structural variations based on NGS approaches with read lengths of 35-300 bases remains a challenge. Single-molecule optical mapping technologies allow the analysis of DNA molecules of up to 2 Mb and as such are suitable for the identification of large-scale genome structural variations, and for de novo genome assemblies when combined with short-read NGS data. Here we present optical mapping data for two human genomes: the HapMap cell line GM12878 and the colorectal cancer cell line HCT116. High molecular weight DNA was obtained by embedding GM12878 and HCT116 cells, respectively, in agarose plugs, followed by DNA extraction under mild conditions. Genomic DNA was digested with KpnI and 310,000 and 296,000 DNA molecules (≥ 150 kb and 10 restriction fragments), respectively, were analyzed per cell line using the Argus optical mapping system. Maps were aligned to the human reference by OPTIMA, a new glocal alignment method. Genome coverage of 6.8× and 5.7× was obtained, respectively; 2.9× and 1.7× more than the coverage obtained with previously available software. Optical mapping allows the resolution of large-scale structural variations of the genome, and the scaffold extension of NGS-based de novo assemblies. OPTIMA is an efficient new alignment method; our optical mapping data provide a resource for genome structure analyses of the human HapMap reference cell line GM12878, and the colorectal cancer cell line HCT116.

Error and Uncertainty in the Accuracy Assessment of Land Cover Maps

NASA Astrophysics Data System (ADS)

Sarmento, Pedro Alexandre Reis

Traditionally the accuracy assessment of land cover maps is performed through the comparison of these maps with a reference database, which is intended to represent the "real" land cover, being this comparison reported with the thematic accuracy measures through confusion matrixes. Although, these reference databases are also a representation of reality, containing errors due to the human uncertainty in the assignment of the land cover class that best characterizes a certain area, causing bias in the thematic accuracy measures that are reported to the end users of these maps. The main goal of this dissertation is to develop a methodology that allows the integration of human uncertainty present in reference databases in the accuracy assessment of land cover maps, and analyse the impacts that uncertainty may have in the thematic accuracy measures reported to the end users of land cover maps. The utility of the inclusion of human uncertainty in the accuracy assessment of land cover maps is investigated. Specifically we studied the utility of fuzzy sets theory, more precisely of fuzzy arithmetic, for a better understanding of human uncertainty associated to the elaboration of reference databases, and their impacts in the thematic accuracy measures that are derived from confusion matrixes. For this purpose linguistic values transformed in fuzzy intervals that address the uncertainty in the elaboration of reference databases were used to compute fuzzy confusion matrixes. The proposed methodology is illustrated using a case study in which the accuracy assessment of a land cover map for Continental Portugal derived from Medium Resolution Imaging Spectrometer (MERIS) is made. The obtained results demonstrate that the inclusion of human uncertainty in reference databases provides much more information about the quality of land cover maps, when compared with the traditional approach of accuracy assessment of land cover maps. None

Mycobacterium avium ss. paratuberculosis Zoonosis – The Hundred Year War – Beyond Crohn’s Disease

PubMed Central

Sechi, Leonardo A.; Dow, Coad Thomas

2015-01-01

The factitive role of Mycobacterium avium ss. paratuberculosis (MAP) in Crohn’s disease has been debated for more than a century. The controversy is due to the fact that Crohn’s disease is so similar to a disease of MAP-infected ruminant animals, Johne’s disease; and, though MAP can be readily detected in the infected ruminants, it is much more difficult to detect in humans. Molecular techniques that can detect MAP in pathologic Crohn’s specimens as well as dedicated specialty labs successful in culturing MAP from Crohn’s patients have provided strong argument for MAP’s role in Crohn’s disease. Perhaps more incriminating for MAP as a zoonotic agent is the increasing number of diseases with which MAP has been related: Blau syndrome, type 1 diabetes, Hashimoto thyroiditis, and multiple sclerosis. In this article, we debate about genetic susceptibility to mycobacterial infection and human exposure to MAP; moreover, it suggests that molecular mimicry between protein epitopes of MAP and human proteins is a likely bridge between infection and these autoimmune disorders. PMID:25788897

A deer (subfamily Cervinae) genetic linkage map and the evolution of ruminant genomes.

PubMed Central

Slate, Jon; Van Stijn, Tracey C; Anderson, Rayna M; McEwan, K Mary; Maqbool, Nauman J; Mathias, Helen C; Bixley, Matthew J; Stevens, Deirdre R; Molenaar, Adrian J; Beever, Jonathan E; Galloway, Susan M; Tate, Michael L

2002-01-01

Comparative maps between ruminant species and humans are increasingly important tools for the discovery of genes underlying economically important traits. In this article we present a primary linkage map of the deer genome derived from an interspecies hybrid between red deer (Cervus elaphus) and Père David's deer (Elaphurus davidianus). The map is approximately 2500 cM long and contains >600 markers including both evolutionary conserved type I markers and highly polymorphic type II markers (microsatellites). Comparative mapping by annotation and sequence similarity (COMPASS) was demonstrated to be a useful tool for mapping bovine and ovine ESTs in deer. Using marker order as a phylogenetic character and comparative map information from human, mouse, deer, cattle, and sheep, we reconstructed the karyotype of the ancestral Pecoran mammal and identified the chromosome rearrangements that have occurred in the sheep, cattle, and deer lineages. The deer map and interspecies hybrid pedigrees described here are a valuable resource for (1) predicting the location of orthologs to human genes in ruminants, (2) mapping QTL in farmed and wild deer populations, and (3) ruminant phylogenetic studies. PMID:11973312

Static anthropometric dimensions in a population of Iranian high school students: considering ethnic differences.

PubMed

Mehrparvar, Amir Houshang; Mirmohammadi, Seyyed Jalil; Hafezi, Rahmatollah; Mostaghaci, Mehrdad; Davari, Mohammad Hossein

2015-05-01

Anthropometric dimensions of the end users should be measured in order to create a basis for manufacturing of different products. This study was designed to measure some static anthropometric dimensions in Iranian high school students, considering ethnic differences. Nineteen static anthropometric dimensions of high school students were measured and compared among different Iranian ethnicities (Fars, Turk, Kurd, Lor, Baluch, and Arab) and different genders. In this study, 9,476 subjects (4,703 boys and 4,773 girls) ages 15 to 18 years in six ethnicities were assessed. The difference among ethnicities was statistically significant for all dimensions (p values < .001 for each dimension). This study showed statistically significant differences in 19 static anthropometric dimensions among high school students regarding gender, age, and ethnicity. © 2014, Human Factors and Ergonomics Society.

In-vitro Thermal Maps to Characterize Human Dental Enamel and Dentin.

PubMed

Lancaster, Paula; Brettle, David; Carmichael, Fiona; Clerehugh, Val

2017-01-01

The crown of a human tooth has an outer layer of highly-mineralized tissue called enamel, beneath which is dentin, a less-mineralized tissue which forms the bulk of the tooth-crown and root. The composition and structure of enamel and dentin are different, resulting in different thermal properties. This gives an opportunity to characterize enamel and dentin from their thermal properties and to visually present the findings as a thermal map. The thermal properties of demineralized enamel and dentin may also be sufficiently different from sound tissue to be seen on a thermal map, underpinning future thermal assessment of caries. The primary aim of this novel study was to produce a thermal map of a sound, human tooth-slice to visually characterize enamel and dentin. The secondary aim was to map a human tooth-slice with demineralized enamel and dentin to consider future diagnostic potential of thermal maps for caries-detection. Two human slices of teeth, one sound and one demineralized from a natural carious lesion, were cooled on ice, then transferred to a hotplate at 30°C where the rewarming-sequence was captured by an infra-red thermal camera. Calculation of thermal diffusivity and thermal conductivity was undertaken, and two methods of data-processing used customized software to produce thermal maps from the thermal characteristic-time-to-relaxation and heat-exchange. The two types of thermal maps characterized enamel and dentin. In addition, sound and demineralized enamel and dentin were distinguishable within both maps. This supports thermal assessment of caries and requires further investigation on a whole tooth.

Radiant thinking and the use of the mind map in nurse practitioner education.

PubMed

Spencer, Julie R; Anderson, Kelley M; Ellis, Kathryn K

2013-05-01

The concept of radiant thinking, which led to the concept of mind mapping, promotes all aspects of the brain working in synergy, with thought beginning from a central point. The mind map, which is a graphical technique to improve creative thinking and knowledge attainment, utilizes colors, images, codes, and dimensions to amplify and enhance key ideas. This technique augments the visualization of relationships and links between concepts, which aids in information acquisition, data retention, and overall comprehension. Faculty can promote students' use of the technique for brainstorming, organizing ideas, taking notes, learning collaboratively, presenting, and studying. These applications can be used in problem-based learning, developing plans of care, health promotion activities, synthesizing disease processes, and forming differential diagnoses. Mind mapping is a creative way for students to engage in a unique method of learning that can expand memory recall and help create a new environment for processing information. Copyright 2013, SLACK Incorporated.

Heat source reconstruction from noisy temperature fields using a gradient anisotropic diffusion filter

NASA Astrophysics Data System (ADS)

Beitone, C.; Balandraud, X.; Delpueyo, D.; Grédiac, M.

2017-01-01

This paper presents a post-processing technique for noisy temperature maps based on a gradient anisotropic diffusion (GAD) filter in the context of heat source reconstruction. The aim is to reconstruct heat source maps from temperature maps measured using infrared (IR) thermography. Synthetic temperature fields corrupted by added noise are first considered. The GAD filter, which relies on a diffusion process, is optimized to retrieve as well as possible a heat source concentration in a two-dimensional plate. The influence of the dimensions and the intensity of the heat source concentration are discussed. The results obtained are also compared with two other types of filters: averaging filter and Gaussian derivative filter. The second part of this study presents an application for experimental temperature maps measured with an IR camera. The results demonstrate the relevancy of the GAD filter in extracting heat sources from noisy temperature fields.

Existence of Lipschitz selections of the Steiner map

NASA Astrophysics Data System (ADS)

Bednov, B. B.; Borodin, P. A.; Chesnokova, K. V.

2018-02-01

This paper is concerned with the problem of the existence of Lipschitz selections of the Steiner map {St}_n, which associates with n points of a Banach space X the set of their Steiner points. The answer to this problem depends on the geometric properties of the unit sphere S(X) of X, its dimension, and the number n. For n≥slant 4 general conditions are obtained on the space X under which {St}_n admits no Lipschitz selection. When X is finite dimensional it is shown that, if n≥slant 4 is even, the map {St}_n has a Lipschitz selection if and only if S(X) is a finite polytope; this is not true if n≥slant 3 is odd. For n=3 the (single-valued) map {St}_3 is shown to be Lipschitz continuous in any smooth strictly-convex two-dimensional space; this ceases to be true in three-dimensional spaces. Bibliography: 21 titles.

$n$ -Dimensional Discrete Cat Map Generation Using Laplace Expansions.

PubMed

Wu, Yue; Hua, Zhongyun; Zhou, Yicong

2016-11-01

Different from existing methods that use matrix multiplications and have high computation complexity, this paper proposes an efficient generation method of n -dimensional ( [Formula: see text]) Cat maps using Laplace expansions. New parameters are also introduced to control the spatial configurations of the [Formula: see text] Cat matrix. Thus, the proposed method provides an efficient way to mix dynamics of all dimensions at one time. To investigate its implementations and applications, we further introduce a fast implementation algorithm of the proposed method with time complexity O(n 4 ) and a pseudorandom number generator using the Cat map generated by the proposed method. The experimental results show that, compared with existing generation methods, the proposed method has a larger parameter space and simpler algorithm complexity, generates [Formula: see text] Cat matrices with a lower inner correlation, and thus yields more random and unpredictable outputs of [Formula: see text] Cat maps.

Generalising the logistic map through the q-product

NASA Astrophysics Data System (ADS)

Pessoa, R. W. S.; Borges, E. P.

2011-03-01

We investigate a generalisation of the logistic map as xn+1 = 1 - axn otimesqmap xn (-1 <= xn <= 1, 0 < a <= 2) where otimesq stands for a generalisation of the ordinary product, known as q-product [Borges, E.P. Physica A 340, 95 (2004)]. The usual product, and consequently the usual logistic map, is recovered in the limit q → 1, The tent map is also a particular case for qmap → ∞. The generalisation of this (and others) algebraic operator has been widely used within nonextensive statistical mechanics context (see C. Tsallis, Introduction to Nonextensive Statistical Mechanics, Springer, NY, 2009). We focus the analysis for qmap > 1 at the edge of chaos, particularly at the first critical point ac, that depends on the value of qmap. Bifurcation diagrams, sensitivity to initial conditions, fractal dimension and rate of entropy growth are evaluated at ac(qmap), and connections with nonextensive statistical mechanics are explored.

Volcanostratigraphic Approach for Evaluation of Geothermal Potential in Galunggung Volcano

NASA Astrophysics Data System (ADS)

Ramadhan, Q. S.; Sianipar, J. Y.; Pratopo, A. K.

2016-09-01

he geothermal systems in Indonesia are primarily associated with volcanoes. There are over 100 volcanoes located on Sumatra, Java, and in the eastern part of Indonesia. Volcanostratigraphy is one of the methods that is used in the early stage for the exploration of volcanic geothermal system to identify the characteristics of the volcano. The stratigraphy of Galunggung Volcano is identified based on 1:100.000 scale topographic map of Tasikmalaya sheet, 1:50.000 scale topographic map and also geological map. The schematic flowchart for evaluation of geothermal exploration is used to interpret and evaluate geothermal potential in volcanic regions. Volcanostratigraphy study has been done on Galunggung Volcano and Talaga Bodas Volcano, West Java, Indonesia. Based on the interpretation of topographic map and analysis of the dimension, rock composition, age and stress regime, we conclude that both Galunggung Volcano and Talaga Bodas Volcano have a geothermal resource potential that deserve further investigation.

The Analysis of Eigenstates of a Few Generalized Quantum Baker’s Maps Using Hadamard and Related Transforms

NASA Astrophysics Data System (ADS)

Meenakshisundaram, N.

Application of the Hadamard and related transforms on a few generalized quantum baker’s maps have been studied. Effectiveness of the Hadamard transform and a new transform which combines the Fourier and the Hadamard transforms, for simplifying the eigenstates or resonances of the quantization of a few generalized baker’s map namely tetradic baker and lazy baker’s map when the Hilbert space dimension is power of 2 has been done by comparing the participation ratios in the transformed basis with respect to the position basis. Several special family of states based on their maximal compression in either Hadamard transform or the new transform are identified and they are related to the ubiquitous Thue-Morse and allied sequences. Evidence is provided that these special family of states as well as average over all eigenstates exhibits multifractal nature.

Optogenetic mapping of brain circuitry

NASA Astrophysics Data System (ADS)

Augustine, George J.; Berglund, Ken; Gill, Harin; Hoffmann, Carolin; Katarya, Malvika; Kim, Jinsook; Kudolo, John; Lee, Li M.; Lee, Molly; Lo, Daniel; Nakajima, Ryuichi; Park, Min Yoon; Tan, Gregory; Tang, Yanxia; Teo, Peggy; Tsuda, Sachiko; Wen, Lei; Yoon, Su-In

2012-10-01

Studies of the brain promise to be revolutionized by new experimental strategies that harness the combined power of optical techniques and genetics. We have mapped the circuitry of the mouse brain by using both optogenetic actuators that control neuronal activity and optogenetic sensors that detect neuronal activity. Using the light-activated cation channel, channelrhodopsin-2, to locally photostimulate neurons allows high-speed mapping of local and long-range circuitry. For example, with this approach we have mapped local circuits in the cerebral cortex, cerebellum and many other brain regions. Using the fluorescent sensor for chloride ions, Clomeleon, allows imaging of the spatial and temporal dimensions of inhibitory circuits in the brain. This approach allows imaging of both conventional "phasic" synaptic inhibition as well as unconventional "tonic" inhibition. The combined use of light to both control and monitor neural activity creates unprecedented opportunities to explore brain function, screen pharmaceutical agents, and potentially to use light to ameliorate psychiatric and neurological disorders.

KINETIC TOMOGRAPHY. I. A METHOD FOR MAPPING THE MILKY WAY’S INTERSTELLAR MEDIUM IN FOUR DIMENSIONS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tchernyshyov, Kirill; Peek, J. E. G.

2017-01-01

We have developed a method for deriving the distribution of the Milky Way’s interstellar medium as a function of longitude, latitude, distance, and line-of-sight velocity. This method takes as input maps of reddening as a function of longitude, latitude, distance, and maps of line emission as a function of longitude, latitude, and line-of-sight velocity. We have applied this method to data sets covering much of the Galactic plane. The output of this method correctly reproduces the line-of-sight velocities of high-mass star-forming regions with known distances from Reid et al. and qualitatively agrees with results from the Milky Way kinematics literature.more » These maps will be useful for measuring flows of gas around the Milky Way’s spiral arms and into and out of giant molecular clouds.« less

Three-dimensional mapping and regulation of action potential propagation in nanoelectronics-innervated tissues.

PubMed

Dai, Xiaochuan; Zhou, Wei; Gao, Teng; Liu, Jia; Lieber, Charles M

2016-09-01

Real-time mapping and manipulation of electrophysiology in three-dimensional (3D) tissues could have important impacts on fundamental scientific and clinical studies, yet realization is hampered by a lack of effective methods. Here we introduce tissue-scaffold-mimicking 3D nanoelectronic arrays consisting of 64 addressable devices with subcellular dimensions and a submillisecond temporal resolution. Real-time extracellular action potential (AP) recordings reveal quantitative maps of AP propagation in 3D cardiac tissues, enable in situ tracing of the evolving topology of 3D conducting pathways in developing cardiac tissues and probe the dynamics of AP conduction characteristics in a transient arrhythmia disease model and subsequent tissue self-adaptation. We further demonstrate simultaneous multisite stimulation and mapping to actively manipulate the frequency and direction of AP propagation. These results establish new methodologies for 3D spatiotemporal tissue recording and control, and demonstrate the potential to impact regenerative medicine, pharmacology and electronic therapeutics.

Three-dimensional mapping and regulation of action potential propagation in nanoelectronics innervated tissues

PubMed Central

Dai, Xiaochuan; Zhou, Wei; Gao, Teng; Liu, Jia; Lieber, Charles M.

2016-01-01

Real-time mapping and manipulation of electrophysiology in three-dimensional (3D) tissues could impact broadly fundamental scientific and clinical studies, yet realization lacks effective methods. Here we introduce tissue-scaffold-mimicking 3D nanoelectronic arrays consisting of 64 addressable devices with subcellular dimensions and sub-millisecond time-resolution. Real-time extracellular action potential (AP) recordings reveal quantitative maps of AP propagation in 3D cardiac tissues, enable in situ tracing of the evolving topology of 3D conducting pathways in developing cardiac tissues, and probe the dynamics of AP conduction characteristics in a transient arrhythmia disease model and subsequent tissue self-adaptation. We further demonstrate simultaneous multi-site stimulation and mapping to manipulate actively the frequency and direction of AP propagation. These results establish new methodologies for 3D spatiotemporal tissue recording and control, and demonstrate the potential to impact regenerative medicine, pharmacology and electronic therapeutics. PMID:27347837

Concept Mapping Strategies: Content, Tools and Assessment for Human Geography

ERIC Educational Resources Information Center

Wehry, Stephanie; Monroe-Ossi, Heather; Cobb, Sharon; Fountain, Cheryl

2012-01-01

This article examines the use of concept mapping for formative and summative assessment of northeast Florida middle school students' knowledge of human geography. The students were participants in an afterschool, academic, college reach-out program that provided opportunities to test concept mapping strategies that support spatial thinking and…

Hyoid expansion with titanium plate and screw: a human cadaveric study using computer-assisted airway measurement.

PubMed

Toh, Song-Tar; Hsu, Pon-Poh; Tan, Kah Leong Alvin; Lu, Kuo-Sun Peter; Han, Hong-Juan

2013-08-01

Hyoid expansion with suspension can potentially increase the upper airway at the hypopharyngeal level, benefitting patients with sleep-related breathing disorder. To document the effect of hyoid expansion using titanium plate and screw on retrolingual hypopharyngeal airway dimension and to compare the airway dimension after isolated hyoid expansion with hyoid expansion + hyomandibular suspension. Anatomical cadaveric dissection study. This study was performed in a laboratory setting using human cadavers. This is an anatomical feasibility study of hyoid expansion using titanium plate and screw on 10 cadaveric human heads and necks. The hyoid bone is trifractured with bony cuts made just medial to the lesser cornu. The freed hyoid body and lateral segments are expanded and stabilized to a titanium adaptation plate. Computer-assisted airway measurement (CAM) was used to measure the airway dimension at the hypopharynx at the level of the tongue base before and after the hyoid expansion. The expanded hyoid bone was then suspended to the mandible, and the airway dimension was measured again with CAM. Airway dimension after isolated hyoid expansion with hyoid expansion with hyomandibular suspension. RESULTS Hyoid expansion with titanium plate and screw resulted in statistical significant increase in the retrolingual hypopharyngeal airway space in all of the 10 human cadavers. The mean (SD) increase in retroglossal area was 33.4 (13.2) mm² (P < .005) (range, 6.0-58.7 mm²). Hyoid expansion with hyomandibular suspension resulted in a greater degree of airway enlargement. The mean (SD) increase in retroglossal area was 99.4 (15.0) mm² (P < .005) (range, 81.9-127.5 mm²). The retrolingual hypopharyngeal airway space increased with hyoid expansion using titanium plate and screw in our human cadaveric study, measured using CAM. The degree of increase is further augmented with hyomandibular suspension.

Modeling adsorption properties of structurally deformed metal–organic frameworks using structure–property map

PubMed Central

Lim, Dae-Woon; Kim, Sungjune; Harale, Aadesh; Yoon, Minyoung; Suh, Myunghyun Paik; Kim, Jihan

2017-01-01

Structural deformation and collapse in metal-organic frameworks (MOFs) can lead to loss of long-range order, making it a challenge to model these amorphous materials using conventional computational methods. In this work, we show that a structure–property map consisting of simulated data for crystalline MOFs can be used to indirectly obtain adsorption properties of structurally deformed MOFs. The structure–property map (with dimensions such as Henry coefficient, heat of adsorption, and pore volume) was constructed using a large data set of over 12000 crystalline MOFs from molecular simulations. By mapping the experimental data points of deformed SNU-200, MOF-5, and Ni-MOF-74 onto this structure–property map, we show that the experimentally deformed MOFs share similar adsorption properties with their nearest neighbor crystalline structures. Once the nearest neighbor crystalline MOFs for a deformed MOF are selected from a structure–property map at a specific condition, then the adsorption properties of these MOFs can be successfully transformed onto the degraded MOFs, leading to a new way to obtain properties of materials whose structural information is lost. PMID:28696307

Cubic map algebra functions for spatio-temporal analysis

USGS Publications Warehouse

Mennis, J.; Viger, R.; Tomlin, C.D.

2005-01-01

We propose an extension of map algebra to three dimensions for spatio-temporal data handling. This approach yields a new class of map algebra functions that we call "cube functions." Whereas conventional map algebra functions operate on data layers representing two-dimensional space, cube functions operate on data cubes representing two-dimensional space over a third-dimensional period of time. We describe the prototype implementation of a spatio-temporal data structure and selected cube function versions of conventional local, focal, and zonal map algebra functions. The utility of cube functions is demonstrated through a case study analyzing the spatio-temporal variability of remotely sensed, southeastern U.S. vegetation character over various land covers and during different El Nin??o/Southern Oscillation (ENSO) phases. Like conventional map algebra, the application of cube functions may demand significant data preprocessing when integrating diverse data sets, and are subject to limitations related to data storage and algorithm performance. Solutions to these issues include extending data compression and computing strategies for calculations on very large data volumes to spatio-temporal data handling.

Effective equilibrium picture in the x y model with exponentially correlated noise

NASA Astrophysics Data System (ADS)

Paoluzzi, Matteo; Marconi, Umberto Marini Bettolo; Maggi, Claudio

2018-02-01

We study the effect of exponentially correlated noise on the x y model in the limit of small correlation time, discussing the order-disorder transition in the mean field and the topological transition in two dimensions. We map the steady states of the nonequilibrium dynamics into an effective equilibrium theory. In the mean field, the critical temperature increases with the noise correlation time τ , indicating that memory effects promote ordering. This finding is confirmed by numerical simulations. The topological transition temperature in two dimensions remains untouched. However, finite-size effects induce a crossover in the vortices proliferation that is confirmed by numerical simulations.

Elliptic Solvers for Mediterranean Sea Ocean Modeling,

DTIC Science & Technology

1984-05-01

KWSP =21*(112+2*21+6) C PARAMETER (NX=IH-2, NY=JHS-2, KQ=NY*((NX+7)/4+1)+(NY+3)/2+8) 9C DOUBLE PRECISION AX,AY,AC(KH),ACKL DIMENSION HD(IH,JH),HT(IH...JH),RS(IH,JH) C COMMON/BV/ W1(IH,JHS),W2(IH,JHS),W3(IH,JHS),W4(IH,JHS) DOUBLE PRECISION WQ DIMENSION MAP(IH,JHS),WQ(JHS,5),WC( KWSP ) EQUIVALENCE (W1(1...AND ALL OTHER MODES C ( TYPICALLY MXKC1 .GE. MXKC2 .GE .MXKC3 ), C MXKC3 = MAX SIZE OF CV FOR RESTART T.S. C ( TYPICALLY MXKC3 = MXKP*3 ). C KWSP

Effective equilibrium picture in the xy model with exponentially correlated noise.

PubMed

Paoluzzi, Matteo; Marconi, Umberto Marini Bettolo; Maggi, Claudio

2018-02-01

We study the effect of exponentially correlated noise on the xy model in the limit of small correlation time, discussing the order-disorder transition in the mean field and the topological transition in two dimensions. We map the steady states of the nonequilibrium dynamics into an effective equilibrium theory. In the mean field, the critical temperature increases with the noise correlation time τ, indicating that memory effects promote ordering. This finding is confirmed by numerical simulations. The topological transition temperature in two dimensions remains untouched. However, finite-size effects induce a crossover in the vortices proliferation that is confirmed by numerical simulations.

One-Dimensional Contact Mode Interdigitated Center of Pressure Sensor (CMIPS)

NASA Technical Reports Server (NTRS)

Xu, Tian-Bing; Kang, Jinho; Park, Cheol; Harrison, Joycelyn S.; Guerreiro, Nelson M.; Hubbard, James E.

2009-01-01

A one dimensional contact mode interdigitated center of pressure sensor (CMIPS) has been developed. The experimental study demonstrated that the CMIPS has the capability to measure the overall pressure as well as the center of pressure in one dimension, simultaneously. A theoretical model for the CMIPS is established here based on the equivalent circuit of the configuration of the CMIPS as well as the material properties of the sensor. The experimental results match well with theoretical modeling predictions. A system mapped with two or more pieces of the CMIPS can be used to obtain information from the pressure distribution in multi-dimensions.

Mycobacterium avium subspecies paratuberculosis - an important food borne pathogen of high public health significance with special reference to India: an update.

PubMed

Chaubey, Kundan Kumar; Singh, Shoor Vir; Gupta, Saurabh; Singh, Manju; Sohal, Jagdip Singh; Kumar, Naveen; Singh, Manoj Kumar; Bhatia, Ashok Kumar; Dhama, Kuldeep

2017-12-01

This review underlines the public health significance of 'Indian Bison Type' of Mycobacterium avium subspecies paratuberculosis (MAP) and also its potential as 'zoonotic infection'. In the absence of control programs, bio-load of MAP is increasing and if we take total population of animals (500 million plus) and human beings (1.23 billion plus) into account, the number of infected animals and human beings will run into millions in India. Our research on screening of over 26,000 domestic livestock for MAP infection using 4 different diagnostic tests (microscopy, culture, ELISA and PCR), during last 31 years has shown that the average bio-load of MAP in the livestock population of India is very high (cattle 43%, buffaloes 36%, goats 23% and sheep 41%). 'Mass screening' of 28,291 human samples between 2008-2016 revealed also high bio-load of MAP. It has been proved that MAP is not in-activated during pasteurization and therefore live bacilli are continuously reaching human population by consumption of even pasteurized milk and other milk products. Live bacilli have also been recovered from meat products and the environment thus illustrating the potential of MAP as pathogen of public health concern. However, at present, there is inadequate scientific evidence to confirm a conclusive link between MAP infection and Johne's disease in ruminants and some cases of Crohn's disease in human beings.

KinMap: a web-based tool for interactive navigation through human kinome data.

PubMed

Eid, Sameh; Turk, Samo; Volkamer, Andrea; Rippmann, Friedrich; Fulle, Simone

2017-01-05

Annotations of the phylogenetic tree of the human kinome is an intuitive way to visualize compound profiling data, structural features of kinases or functional relationships within this important class of proteins. The increasing volume and complexity of kinase-related data underlines the need for a tool that enables complex queries pertaining to kinase disease involvement and potential therapeutic uses of kinase inhibitors. Here, we present KinMap, a user-friendly online tool that facilitates the interactive navigation through kinase knowledge by linking biochemical, structural, and disease association data to the human kinome tree. To this end, preprocessed data from freely-available sources, such as ChEMBL, the Protein Data Bank, and the Center for Therapeutic Target Validation platform are integrated into KinMap and can easily be complemented by proprietary data. The value of KinMap will be exemplarily demonstrated for uncovering new therapeutic indications of known kinase inhibitors and for prioritizing kinases for drug development efforts. KinMap represents a new generation of kinome tree viewers which facilitates interactive exploration of the human kinome. KinMap enables generation of high-quality annotated images of the human kinome tree as well as exchange of kinome-related data in scientific communications. Furthermore, KinMap supports multiple input and output formats and recognizes alternative kinase names and links them to a unified naming scheme, which makes it a useful tool across different disciplines and applications. A web-service of KinMap is freely available at http://www.kinhub.org/kinmap/ .

Mapping simulated scenes with skeletal remains using differential GPS in open environments: an assessment of accuracy and practicality.

PubMed

Walter, Brittany S; Schultz, John J

2013-05-10

Scene mapping is an integral aspect of processing a scene with scattered human remains. By utilizing the appropriate mapping technique, investigators can accurately document the location of human remains and maintain a precise geospatial record of evidence. One option that has not received much attention for mapping forensic evidence is the differential global positioning (DGPS) unit, as this technology now provides decreased positional error suitable for mapping scenes. Because of the lack of knowledge concerning this utility in mapping a scene, controlled research is necessary to determine the practicality of using newer and enhanced DGPS units in mapping scattered human remains. The purpose of this research was to quantify the accuracy of a DGPS unit for mapping skeletal dispersals and to determine the applicability of this utility in mapping a scene with dispersed remains. First, the accuracy of the DGPS unit in open environments was determined using known survey markers in open areas. Secondly, three simulated scenes exhibiting different types of dispersals were constructed and mapped in an open environment using the DGPS. Variables considered during data collection included the extent of the dispersal, data collection time, data collected on different days, and different postprocessing techniques. Data were differentially postprocessed and compared in a geographic information system (GIS) to evaluate the most efficient recordation methods. Results of this study demonstrate that the DGPS is a viable option for mapping dispersed human remains in open areas. The accuracy of collected point data was 11.52 and 9.55 cm for 50- and 100-s collection times, respectfully, and the orientation and maximum length of long bones was maintained. Also, the use of error buffers for point data of bones in maps demonstrated the error of the DGPS unit, while showing that the context of the dispersed skeleton was accurately maintained. Furthermore, the application of a DGPS for accurate scene mapping is discussed and guidelines concerning the implementation of this technology for mapping human scattered skeletal remains in open environments are provided. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Shifting Attention Between Visual Dimensions as a Source of Switch Costs.

PubMed

Elchlepp, Heike; Best, Maisy; Lavric, Aureliu; Monsell, Stephen

2017-04-01

Task-switching experiments have documented a puzzling phenomenon: Advance warning of the switch reduces but does not eliminate the switch cost. Theoretical accounts have posited that the residual switch cost arises when one selects the relevant stimulus-response mapping, leaving earlier perceptual processes unaffected. We put this assumption to the test by seeking electrophysiological markers of encoding a perceptual dimension. Participants categorized a colored letter as a vowel or consonant or its color as "warm" or "cold." Orthogonally to the color manipulation, some colors were eight times more frequent than others, and the letters were in upper- or lowercase. Color frequency modulated the electroencephalogram amplitude at around 150 ms when participants repeated the color-classification task. When participants switched from the letter task to the color task, this effect was significantly delayed. Thus, even when prepared for, a task switch delays or prolongs encoding of the relevant perceptual dimension.

From spinning conformal blocks to matrix Calogero-Sutherland models

NASA Astrophysics Data System (ADS)

Schomerus, Volker; Sobko, Evgeny

2018-04-01

In this paper we develop further the relation between conformal four-point blocks involving external spinning fields and Calogero-Sutherland quantum mechanics with matrix-valued potentials. To this end, the analysis of [1] is extended to arbitrary dimensions and to the case of boundary two-point functions. In particular, we construct the potential for any set of external tensor fields. Some of the resulting Schrödinger equations are mapped explicitly to the known Casimir equations for 4-dimensional seed conformal blocks. Our approach furnishes solutions of Casimir equations for external fields of arbitrary spin and dimension in terms of functions on the conformal group. This allows us to reinterpret standard operations on conformal blocks in terms of group-theoretic objects. In particular, we shall discuss the relation between the construction of spinning blocks in any dimension through differential operators acting on seed blocks and the action of left/right invariant vector fields on the conformal group.

Contrasting faith-based and traditional substance abuse treatment programs.

PubMed

Neff, James Alan; Shorkey, Clayton T; Windsor, Liliane Cambraia

2006-01-01

This article (a) discusses the definition of faith-based substance abuse treatment programs, (b) juxtaposes Durkheim's theory regarding religion with treatment process model to highlight key dimensions of faith-based and traditional programs, and (c) presents results from a study of seven programs to identify key program dimensions and to identify differences/similarities between program types. Focus group/Concept Mapping techniques yielded a clear "spiritual activities, beliefs, and rituals" dimension, rated as significantly more important to faith-based programs. Faith-based program staff also rated "structure and discipline" as more important and "work readiness" as less important. No differences were found for "group activities/cohesion" and "role modeling/mentoring," "safe, supportive environment," and "traditional treatment modalities." Programs showed substantial similarities with regard to core social processes of treatment such as mentoring, role modeling, and social cohesion. Implications are considered for further research on treatment engagement, retention, and other outcomes.

Mean first passage time of active Brownian particle in one dimension

NASA Astrophysics Data System (ADS)

Scacchi, A.; Sharma, A.

2018-02-01

We investigate the mean first passage time of an active Brownian particle in one dimension using numerical simulations. The activity in one dimension is modelled as a two state model; the particle moves with a constant propulsion strength but its orientation switches from one state to other as in a random telegraphic process. We study the influence of a finite resetting rate r on the mean first passage time to a fixed target of a single free active Brownian particle and map this result using an effective diffusion process. As in the case of a passive Brownian particle, we can find an optimal resetting rate r* for an active Brownian particle for which the target is found with the minimum average time. In the case of the presence of an external potential, we find good agreement between the theory and numerical simulations using an effective potential approach.

Orthogonal stimulus-response compatibility effects emerge even when the stimulus position is task irrelevant.

PubMed

Nishimura, Akio; Yokosawa, Kazuhiko

2006-06-01

The above-right/below-left mapping advantage with vertical stimuli and horizontal responses is known as the orthogonal stimulus-response compatibility (SRC) effect. We investigated whether the orthogonal SRC effect emerges with irrelevant stimulus dimensions. In Experiment 1, participants responded with a right or left key press to the colour of the stimulus presented above or below the fixation. We observed an above-right/below-left advantage (orthogonal Simon effect). In Experiment 2, we manipulated the polarity in the response dimension by varying the horizontal location of the response set. The orthogonal Simon effect decreased and even reversed as the left response code became more positive. This result provides evidence for the automatic activation of the positive and negative response codes by the corresponding positive and negative stimulus codes. These findings extended the orthogonal SRC effect based on coding asymmetry to an irrelevant stimulus dimension.

The Doctorate of the Bologna Process Third Cycle: Mapping the Dimensions and Impact of the European Higher Education Area

ERIC Educational Resources Information Center

Carter, Susan; Fazey, John; Gonzalez Geraldo, Jose Luis; Trevitt, Chris

2010-01-01

The European Union Bologna Process is a significant agent for internationalization of education. Acknowledging fiscal and political drivers, this article shows that Bologna inclusion of the doctoral degree offers potential for enhanced doctoral experience. Interest in transferability of doctoral education across national borders, standardization…

EWork in Southern Europe. IES Report.

ERIC Educational Resources Information Center

Altieri, G.; Birindelli, L.; Bracaglia, P.; Tartaglione, C.; Albarracin, D.; Vaquero, J.; Fissamber, V.

Part of the EMERGENCE project to measure and map employment relocation in a global economy in the new communications environment, this report on eWork in southern Europe (SE) combines results of a European employer survey, case studies, and data from other sources. Chapter 1 analyzes national and sector dimensions. Chapter 2 studies eWork practice…

The missing dimension: the relevance of people's conception of time.

PubMed

Norgate, Sarah H; Davies, Nigel; Speed, Chris; Cherrett, Tom; Dickinson, Janet

2014-02-01

While a timely conceptual innovation for the digital age, the "map" proposed by Bentley et al. would benefit from strengthening through the inclusion of a non-clock-time perspective. In this way, there could be new hypotheses developed which could be applied and tested relevant to more diverse societies, cultures, and individuals.

The Dimensions of the Solar System

ERIC Educational Resources Information Center

Schneider, Stephen E.; Davis, Kathleen S.

2007-01-01

A few new wrinkles have been added to the popular activity of building a scale model of the solar system. Students can learn about maps and scaling using easily accessible online resources that include satellite images. This is accomplished by taking advantage of some of the special features of Google Earth. This activity gives students a much…