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Sample records for marc david seligman

  1. Seligman's Helplessness: Who Shall Overcome?

    ERIC Educational Resources Information Center

    Gregory, Mary K.

    1975-01-01

    The author discusses Seligman's research on helplessness: how it is learned, what factors influence its formation, how it is unlearned and the implications of his research for counseling depressed clients. The author clains that directive counseling would be quite helpful for depressed and helpless clients. (SE)

  2. Record Formatting: MARC AMC.

    ERIC Educational Resources Information Center

    Weber, Lisa B.

    1990-01-01

    Discusses how archivists use the MARC AMC (Archival and Manuscripts Control) format for descriptive information about archival materials. Modifications that MARC AMC introduced to the standard MARC bibliographic formats are explained, and examples of a record in AMC formats on different bibliographic utilities are given. (24 references) (LRW)

  3. Canadian Experience with MARC.

    ERIC Educational Resources Information Center

    Chapple, Sharon E.

    Canadian libraries have used Machine-readable Cataloging (MARC) since its beginnings in 1966, mainly for speeding up the cataloging of American imprints. The lack of bilingualism in Library of Congress MARC records was a major deficiency in Canada where bilingual access points are provided for all publications in the national bibliography,…

  4. MARC Exit Strategies.

    ERIC Educational Resources Information Center

    Tennant, Roy

    2002-01-01

    Questions the value of MARC records and considers the need for a new bibliographic standard. Topics include language and hierarchy; problems with print and electronic copies of the same work, especially in union catalogs; XML; merging records and authority control; and what to do with existing MARC records. (LRW)

  5. MARC; its History and Implications.

    ERIC Educational Resources Information Center

    Avram, Henriette D.

    The Library of Congress presents the history of its Machine Readable Cataloging (MARC) system. Descriptions of MARC pilot projects and distribution services are followed by a discussion of several conversion projects undertaken by libraries in order to implement MARC. Then MARC's influence on standardization of formats for information interchange,…

  6. Martin E. P. Seligman: 2006 award for distinguished scientific contributions.

    PubMed

    2006-11-01

    Presents the citation for Martin E. P. Seligman, who received the Award for Distinguished Scientific Contributions "for a career spent charging creatively ahead of his field and then pulling his colleagues along." A brief profile and a selected bibliography, as well as the award address, Positive Psychotherapy, accompany the citation. ((c) 2006 APA, all rights reserved).

  7. Marc Chagall: "Wild Poppies."

    ERIC Educational Resources Information Center

    White, Carolyn

    1987-01-01

    Based on a full-color reproduction of Marc Chagall's painting, "Wild Poppies," the goals of this lesson plan are to introduce students to artist's use of dreams and memories in making art, to communicate the idea that artists include their visual memories of people and things they love in their artwork, and to introduce the concepts of line and…

  8. MARCS model atmospheres

    NASA Astrophysics Data System (ADS)

    Plez, B.

    2008-12-01

    In this review presented at the Symposium A Stellar Journey in Uppsala, June 2008, I give an account of the historical development of the MARCS code, and its premises from the first version published in 1975 to the 2008 grid. The primary driver for the development team who constantly strive to include the best possible physical data, is the science that can be done with the models. A few preliminary comparisons of M star model spectra to spectrophotometric observations are presented. Particular results related to opacity effects are discussed. The size of errors in spectral energy distribution (SED) and model thermal stratification is estimated for different densities of wavelength sampling. The number of points used in the MARCS 2008 grid (108 000) is large enough to ensure errors of only a few K in all models of the grid, except the optically very thin layers of metal-poor stars. Errors in SEDs may reach about 10% locally in the UV. The published sampled SEDs are thus adequate to compute synthetic broadband photometry, but higher resolution spectra will be computed in the near future and published as well on the MARCS site (marcs.astro.uu.se). Test model calculations with TiO line opacity accounted for in scattering show significant cooling of the upper atmospheric layers of red giants. Rough estimates of radiative and collisional time scales for electronic transitions of TiO indicate that scattering may well be the dominant mechanism in these lines. However, models constructed with this hypothesis are incompatible with optical observations of TiO (Arcturus) or IR observations of OH (Betelgeuse), although they may succeed in explaining H2O line observations. More work is needed in that direction.

  9. Talent Developed: Conversations with Masters in the Arts and Sciences. Martin Seligman.

    ERIC Educational Resources Information Center

    Subotnik, Rena F.

    2000-01-01

    This interview with Martin Seligman, a past-president of the American Psychological Association and the author of seminal works in the areas of both learned helplessness and optimism, discusses his interest in positive psychology and giftedness, fostering creative genius, his childhood and move from philosophy to psychology, and future plans.…

  10. Exposing the Glosses in Seligman and Fowler's (2011) Straw-Man Arguments

    ERIC Educational Resources Information Center

    Dyckman, John

    2011-01-01

    The author was disappointed to see an entire special issue of the "American Psychologist" (January 2011) devoted to military psychology, but he was especially concerned about the one-sided moral justifications presented by Seligman and Fowler (2011) in the final article of the issue. The author feels they misrepresented potential objections to…

  11. A Critical Review of Seligman's Laboratory Experiments on Learned Helplessness and Depression in Humans

    ERIC Educational Resources Information Center

    Costello, Charles G.

    1978-01-01

    Six laboratory experiments on learned helplessness and depression in humans reported by Seligman and his colleagues were critically reviewed. A number of methodological and conceptual problems were discussed. Suggests that it is important for psychologists to scrutinize psychological theories in order to assess their conceptual clarity and…

  12. SLICE/MARC-O: Description of Services. Second Revised Edition.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Libraries, Oklahoma City.

    Following the discussions of: what is SLICE, what is MARC, what is MARC-O, and what is SLICE/MARC-O are descriptions of the five services offered by SLICE/MARC-O. These services are: (1) cataloging data search and print, (2) MARC record and search and copy, (3) standard S.D.I. current awareness, (4) custom S.D.I. current awareness and (5) SLICE…

  13. Toxicity of sulcotrione and grape marc on Vicia faba cells.

    PubMed

    Sta, Chaima; Goujon, Eric; Ferjani, Ezzeddine; Ledoigt, Gérard

    2014-12-10

    The cell toxicity of sulcotrione, a selective triketone herbicide, was evaluated on Vicia faba. Sulcotrione, trademark Mikado, grape marc, and mixtures of sulcotrione or Mikado with grape marc induced cell death. Addition of grape marc to either sulcotrione or Mikado enhanced cell death, especially with Mikado. Addition of grape marc to herbicides, sulcotrione, or Mikado resulted in different expression of genes usually associated with cell stress. Mixtures of grape marc and herbicides enhanced transcript accumulation for ubiquitin, hsp 70, and cytosolic superoxide dismutase, but did not change ascorbate peroxidase transcript accumulation. The results thus provide evidence that sulcotrione, Mikado, and mixtures with grape marc can trigger cell death and specific gene expressions. Cocktails of products with sulcotrione, such as commercial additives and grape marc, can modify biological features of pesticide. Moreover, grape marc differently enhanced cell toxicity of sulcotrione and Mikado, suggesting a synergy between pesticide products and grape marc.

  14. MARC for Cataloguers: An Explanation of its Use.

    ERIC Educational Resources Information Center

    Irvine, Ruth

    A seminar on practical MARC cataloging was held at Southampton University library in April 1972. MARC is an acronym for Machine Readable Cataloging, a system devised by the Library of Congress and developed with them by the British National Bibliography. MARC enables the catalog data for any given work to be read and manipulated by the computer,…

  15. NUC Reporting and MARC Redistribution: Their Functional Confluence and Its Implications for a Redefinition of the MARC Format

    ERIC Educational Resources Information Center

    Weisbrod, David L.

    1977-01-01

    This paper examines the development of NUC reporting in machine-readable form and MARC record distribution. Some technical requirements are identified and discussed in terms of their implications for a redefinition of MARC format. (Author/KP)

  16. Processing of MARC Tapes for Cooperative Use

    ERIC Educational Resources Information Center

    Bierman, Kenneth John; Blue, Betty Jean

    1970-01-01

    Discusses a centralized data base of MARC II records which is operated by the Oklahoma Department of Libraries and is available to any library in the state. The history, creation, operation, uses, advantages, disadvantages, cost and future plans of the data base are included, as well as flowcharts (both system and detail) and sample outputs.…

  17. Is an Attributional Analysis of the Learned Helplessness Phenomenon Viable? A Critique of the Abramson-Seligman-Teasdale Reformulation

    ERIC Educational Resources Information Center

    Dintzer, Leonard; Wortman, Camille B.

    1978-01-01

    The reformulated learned helplessness model of depression (Abramson, Seligman, Teasdale 1978) was examined. Argues that unless it is possible to specify the conditions under which a given attribution will be made, the model becomes circular and lacks predictive power. Discusses Abramson et al.'s suggestions for therapy and prevention. (Editor/RK)

  18. CAVEing the MMPI for an Optimism-Pessimism Scale: Seligman's Attributional Model and the Assessment of Explanatory Style.

    ERIC Educational Resources Information Center

    Colligan, Robert C.; And Others

    1994-01-01

    Developed bipolar Minnesota Multiphasic Personality Inventory (MMPI) Optimism-Pessimism (PSM) scale based on results on Content Analysis of Verbatim Explanation applied to MMPI. Reliability and validity indices show that PSM scale is highly accurate and consistent with Seligman's theory that pessimistic explanatory style predicts increased…

  19. Remembering David N. Schramm

    NASA Astrophysics Data System (ADS)

    Turner, Michael S.

    2001-03-01

    Eight months ago David Schramm died doing one of things he loved most - flying his airplane, known as Big-bang Aviation. He was to have been at this meeting doing something that he loved even more - going to scientific meetings to talk about the latest results and to renew friendships...

  20. Interview with David Moore

    ERIC Educational Resources Information Center

    Rossman, Allan; Dietz, E. Jacquelin; Moor, David

    2013-01-01

    David Moore is Professor Emeritus of Statistics at Purdue University. He served as the first President of the International Association for Statistical Education (IASE) from 1993-1995 and as President of the American Statistical Association (ASA) in 1998. He is a Fellow of the ASA and of the IMS and was awarded the ASA's Founders Award in…

  1. David Gale: Restless Pioneer

    ERIC Educational Resources Information Center

    Meyer, Walter

    2006-01-01

    David Gale was one of the mathematicians responsible for the modern form of the theory of duality in linear programming and the associated proof of the minimax theorem in the theory of games. He is a member of the National Academy of Sciences and is Professor Emeritus of Mathematics and Operations Research at the University of California at…

  2. Historic American Buildings Survey Marc Blair Photographer, Summer 1966 SOUTHWEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Historic American Buildings Survey Marc Blair Photographer, Summer 1966 SOUTHWEST INTERIOR DETAIL - Grace Protestant Episcopal Church, 1041 Wisconsin Avenue Northwest, Washington, District of Columbia, DC

  3. Historic American Buildings Survey Marc Blair Photographer, summer 1966 WEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Historic American Buildings Survey Marc Blair Photographer, summer 1966 WEST (entry) END with CHOIR LOFT - Grace Protestant Episcopal Church, 1041 Wisconsin Avenue Northwest, Washington, District of Columbia, DC

  4. Historic American Buildings Survey Marc Blair Photographer, summer 1966 DETAIL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Historic American Buildings Survey Marc Blair Photographer, summer 1966 DETAIL of SOUTH ELEVATION - Grace Protestant Episcopal Church, 1041 Wisconsin Avenue Northwest, Washington, District of Columbia, DC

  5. Historic American Buildings Survey Marc Blair Photographer, summer 1966 SOUTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Historic American Buildings Survey Marc Blair Photographer, summer 1966 SOUTH ELEVATION from SOUTHWEST - Grace Protestant Episcopal Church, 1041 Wisconsin Avenue Northwest, Washington, District of Columbia, DC

  6. David Keynes Hill.

    PubMed

    Huxley, Andrew

    2003-01-01

    David Hill followed his father, A.V. Hill FRS, into the study of muscular contraction. Using a wide range of experimental techniques, he made several important advances of which the most important was the discovery of the 'short-range elastic component', a phenomenon which implied that even in the resting state there was an interaction between the thick (myosin) and thin (actin) filaments. He also studied physical changes in nerve when stimulated.

  7. Antioxidant Extraction and Biogas Production from Pomegranate Marc

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The pomegranate marc (PM), by-product from pomegranate juice processing, has not been effectively utilized. The objectives of this study were to (1) determine the yields and properties of antioxidants (total phenolics) extracted from peels and seeds of pomegranate marc in wet and dry forms, and (2)...

  8. David Hartley's Newtonian neuropsychology.

    PubMed

    Smith, C U

    1987-04-01

    David Hartley's association psychology has been immensely influential. His vibrationist neurophysiology has, in contrast, been largely overlooked and forgotten. Hartley's vibration theory is examined. On the one hand it is shown how closely it is related to Sir Isaac Newton's mathematical physics and on the other how well it complements the association theory. The vibration theory, indeed, strongly influenced Hartley's associationist psychology and hence is of more than merely antiquarian interest. Although Hartley's understanding of the central nervous system has long been superseded, his general ideas prefigure some aspects of contemporary neurophysiology and philosophy of mind and thus provide a further reason for rescuing his vibrationism from oblivion.

  9. The mammalian molybdenum enzymes of mARC.

    PubMed

    Ott, Gudrun; Havemeyer, Antje; Clement, Bernd

    2015-03-01

    The "mitochondrial amidoxime reducing component" (mARC) is the most recently discovered molybdenum-containing enzyme in mammals. All mammalian genomes studied to date contain two mARC genes: MARC1 and MARC2. The proteins encoded by these genes are mARC-1 and mARC-2 and represent the simplest form of eukaryotic molybdenum enzymes, only binding the molybdenum cofactor. In the presence of NADH, mARC proteins exert N-reductive activity together with the two electron transport proteins cytochrome b5 type B and NADH cytochrome b5 reductase. This enzyme system is capable of reducing a great variety of N-hydroxylated substrates. It plays a decisive role in the activation of prodrugs containing an amidoxime structure, and in detoxification pathways, e.g., of N-hydroxylated purine and pyrimidine bases. It belongs to a group of drug metabolism enzymes, in particular as a counterpart of P450 formed N-oxygenated metabolites. Its physiological relevance, on the other hand, is largely unknown. The aim of this article is to summarize our current knowledge of these proteins with a special focus on the mammalian enzymes and their N-reductive activity.

  10. Evaluation of MARC for the analysis of rotating composite blades

    NASA Technical Reports Server (NTRS)

    Bartos, Karen F.; Ernst, Michael A.

    1993-01-01

    The suitability of the MARC code for the analysis of rotating composite blades was evaluated using a four-task process. A nonlinear displacement analysis and subsequent eigenvalue analysis were performed on a rotating spring mass system to ensure that displacement-dependent centrifugal forces were accounted for in the eigenvalue analysis. Normal modes analyses were conducted on isotropic plates with various degrees of twist to evaluate MARC's ability to handle blade twist. Normal modes analyses were conducted on flat composite plates to validate the newly developed coupled COBSTRAN-MARC methodology. Finally, normal modes analyses were conducted on four composite propfan blades that were designed, analyzed, and fabricated at NASA Lewis Research Center. Results were compared with experimental data. The research documented herein presents MARC as a viable tool for the analysis of rotating composite blades.

  11. David Crighton 1942 2000

    NASA Astrophysics Data System (ADS)

    Ffowcs Williams, John E.

    2001-06-01

    David Crighton was struck down by cancer in his fifty-eighth year. He was then at the height of his career and was one of the most admired personalities in fluid mechanics. He had specialized in wave theory, helping to understand and solve problems of practical importance using the full power of mathematical method. Efforts to control the sound and vibration caused by unsteady flow were never far from his thinking, and Crighton's contribution to those efforts has changed significantly the way the subject is viewed. Having first attracted him into the field and never losing my interest in the way he was influencing it, it is natural that I should comment on the technical developments while looking back on Crighton's professional life. The subject has changed a great deal and there are now many more researchers involved in its study, many of whom rely on techniques that Crighton pioneered really powerful mathematical methods. But the basic problems remain: powerful flows are noisy.

  12. David Morrison on Lake Vostok

    NASA Video Gallery

    Dr. David Morrison discusses the implications of research possibilities at Lake Vostok, one of the largest subglacial lakes located over two miles beneath the ice in Antarctica. The lake has been c...

  13. Memories of David Kirzhnits

    NASA Astrophysics Data System (ADS)

    Bolotovsky, B. M.

    2013-06-01

    In the mid-1950s, a new staff member appeared at the Theory Division of the Physical Institute of the Academy of Sciences (FIAN): David Abramovich Kirzhnits. A Moscow State University alumnus, after graduation he had been assigned to a large defense plant in the city of Gorky, where he had worked for several years as an engineer. He was "liberated" from there by Igor Evgenyevich Tamm, our department head, who managed to transfer him to FIAN. Igor Evgenyevich knew D. A. Kirzhnits - they had met in Moscow before Kirzhnits finished university. At that time Kirzhnits was performing thesis work with professor A. S. Kompaneyets as academic adviser. At his adviser's suggestion, D. Kirzhnits consulted with I. E. Tamm on questions pertaining to the thesis topic. I. E. Tamm took a great liking for the diploma student, and he even wanted to recruit D. A. Kirzhnits for the Theory Division immediately after graduation. But at that time (1949) this proved impossible for several reasons. First, D. Kirzhnits was, as they say, an "invalid of the fifth group" - a Jew - which during those years of violent struggle against cosmopolitanismb often proved an obstacle in looking for work. Second, during the years of mass repressions D. Kirzhnits' father had been arrested on treason charges (according to the charges, he had wanted to sell the Far East to Japan). After intensive investigation his father was released, but he lived only a little longer. Reports of this also could have impeded his acceptance. Third, Igor Evgenyevich didn't have enough weight in officials' eyes at that time and so was unable to overcome "first" and "second."...

  14. A Comparison of Positive Outcome Expectancies: A Review of the Theories of M. F. Scheier, C. S. Carver, M. E. P. Seligman, and C. R. Snyder.

    ERIC Educational Resources Information Center

    Bird, William A.

    Research has shown that optimistic and pessimistic outcome expectancy evaluations are associated with adaptive and maladaptive levels of psychological functioning, physical wellness, and health recovery issues. The research of M. F. Scheier, C. S. Carver, M. E. P. Seligman, and C. R. Snyder supports the hypothesis that elevated optimism or…

  15. Nitrite Reductase and Nitric-oxide Synthase Activity of the Mitochondrial Molybdopterin Enzymes mARC1 and mARC2*

    PubMed Central

    Sparacino-Watkins, Courtney E.; Tejero, Jesús; Sun, Bin; Gauthier, Marc C.; Thomas, John; Ragireddy, Venkata; Merchant, Bonnie A.; Wang, Jun; Azarov, Ivan; Basu, Partha; Gladwin, Mark T.

    2014-01-01

    Mitochondrial amidoxime reducing component (mARC) proteins are molybdopterin-containing enzymes of unclear physiological function. Both human isoforms mARC-1 and mARC-2 are able to catalyze the reduction of nitrite when they are in the reduced form. Moreover, our results indicate that mARC can generate nitric oxide (NO) from nitrite when forming an electron transfer chain with NADH, cytochrome b5, and NADH-dependent cytochrome b5 reductase. The rate of NO formation increases almost 3-fold when pH was lowered from 7.5 to 6.5. To determine if nitrite reduction is catalyzed by molybdenum in the active site of mARC-1, we mutated the putative active site cysteine residue (Cys-273), known to coordinate molybdenum binding. NO formation was abolished by the C273A mutation in mARC-1. Supplementation of transformed Escherichia coli with tungsten facilitated the replacement of molybdenum in recombinant mARC-1 and abolished NO formation. Therefore, we conclude that human mARC-1 and mARC-2 are capable of catalyzing reduction of nitrite to NO through reaction with its molybdenum cofactor. Finally, expression of mARC-1 in HEK cells using a lentivirus vector was used to confirm cellular nitrite reduction to NO. A comparison of NO formation profiles between mARC and xanthine oxidase reveals similar Kcat and Vmax values but more sustained NO formation from mARC, possibly because it is not vulnerable to autoinhibition via molybdenum desulfuration. The reduction of nitrite by mARC in the mitochondria may represent a new signaling pathway for NADH-dependent hypoxic NO production. PMID:24500710

  16. Marshall Amateur Radio Club experiment (MARCE) post flight data analysis

    NASA Technical Reports Server (NTRS)

    Rupp, Charles C.

    1987-01-01

    The Marshall Amateur Radio Club Experiment (MARCE) data system, the data recorded during the flight of STS-61C, the manner in which the data was reduced to engineering units, and the performance of the student experiments determined from the data are briefly described.

  17. Extraction modeling and activities of antioxidants from pomegranate marc

    Technology Transfer Automated Retrieval System (TEKTRAN)

    To develop value-added antioxidants from the peel and seeds of pomegranate marc, a by-product after pomegranate juice processing, the effects of drying before extraction and processing parameters on the extraction kinetics and product properties were systematically studied using water as an environm...

  18. STS-97 Crew Interview: Marc Garneau, MS2

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The STS-97 Mission Specialist Marc Garneau is seen being interviewed. He answers questions about his inspiration to become an astronaut, his career path, and his training. He gives details on the mission's goals and significance, its payload, the rendezvous with the International Space Station (ISS), and what it will be like to work knowing there is already a crew on board the ISS.

  19. David Hume on Competent Judges

    ERIC Educational Resources Information Center

    Eaton, Marcia Muelder

    2004-01-01

    This essay is the eighth in an occasional series on past treatments of major issues in arts education policy from antiquity through the twentieth century. The essay on which it is based, David Hume's "Of the Standard of Taste," originally published in 1757, is too extensive to be reprinted here, but it is easily accessible in the public domain.…

  20. Experiments on Utilization of JAPAN/MARC by a Personal Computer

    NASA Astrophysics Data System (ADS)

    Asakura, Syuzo

    Realizing JAPAN/MARC for a personal computer, classification of books and collection of bibliographic data assisted with JAPAN/MARC become easy. In this paper, an experimental method of transforming JAPAN/MARC from tape to MS-DOS floppy disk is described in detail. The standard record form for a personal computer and the exchange record form for database language is proposed. The summary of the results are : JAPAN/MARC becomes available to a personal computer. The new record forms make it easy to use JAPAN/MARC by a personal computer and to exchange bibliographic data to other personal computer systems for a library.

  1. [Movement disorders in David Copperfield].

    PubMed

    Garćia Ruiz, P J; Gulliksen, L L

    1999-01-01

    Charles Dickens' novels are a source of vivid neurological descriptions. Besides Pickwickian syndrome, many other neurological descriptions can be found in Dickens' novels. David Copperfield contains several characters with movement disorders including generalized dystonia (Mr. Uriah Heep), restless legs syndrome (the waiter), cervical dystonia (Mr. Sharp) and spasmodic dysphonia (Mr. Creakle). These neurological descriptions an probably based on the observation of actual patients. PMID:10570623

  2. Grape marc reduces methane emissions when fed to dairy cows.

    PubMed

    Moate, P J; Williams, S R O; Torok, V A; Hannah, M C; Ribaux, B E; Tavendale, M H; Eckard, R J; Jacobs, J L; Auldist, M J; Wales, W J

    2014-01-01

    Grape marc (the skins, seeds, stalk, and stems remaining after grapes have been pressed to make wine) is currently a by-product used as a feed supplement by the dairy and beef industries. Grape marc contains condensed tannins and has high concentrations of crude fat; both these substances can reduce enteric methane (CH4) production when fed to ruminants. This experiment examined the effects of dietary supplementation with either dried, pelleted grape marc or ensiled grape marc on yield and composition of milk, enteric CH4 emissions, and ruminal microbiota in dairy cows. Thirty-two Holstein dairy cows in late lactation were offered 1 of 3 diets: a control (CON) diet; a diet containing dried, pelleted grape marc (DGM); and a diet containing ensiled grape marc (EGM). The diet offered to cows in the CON group contained 14.0kg of alfalfa hay dry matter (DM)/d and 4.3kg of concentrate mix DM/d. Diets offered to cows in the DGM and EGM groups contained 9.0kg of alfalfa hay DM/d, 4.3kg of concentrate mix DM/d, and 5.0kg of dried or ensiled grape marc DM/d, respectively. These diets were offered individually to cows for 18d. Individual cow feed intake and milk yield were measured daily and milk composition measured on 4d/wk. Individual cow CH4 emissions were measured by the SF6 tracer technique on 2d at the end of the experiment. Ruminal bacterial, archaeal, fungal, and protozoan communities were quantified on the last day of the experiment. Cows offered the CON, DGM, and EGM diets, ate 95, 98, and 96%, respectively, of the DM offered. The mean milk yield of cows fed the EGM diet was 12.8kg/cow per day and was less than that of cows fed either the CON diet (14.6kg/cow per day) or the DGM diet (15.4kg/cow per day). Feeding DGM and EGM diets was associated with decreased milk fat yields, lower concentrations of saturated fatty acids, and enhanced concentrations of mono- and polyunsaturated fatty acids, in particular cis-9,trans-11 linoleic acid. The mean CH4 emissions were

  3. Processing of SeaMARC swath sonar imagery

    SciTech Connect

    Pratson, L.; Malinverno, A.; Edwards, M.; Ryan, W. )

    1990-05-01

    Side-scan swath sonar systems have become an increasingly important means of mapping the sea floor. Two such systems are the deep-towed, high-resolution SeaMARC I sonar, which has a variable swath width of up to 5 km, and the shallow-towed, lower-resolution SeaMARC II sonar, which has a swath width of 10 km. The sea-floor imagery of acoustic backscatter output by the SeaMARC sonars is analogous to aerial photographs and airborne side-looking radar images of continental topography. Geologic interpretation of the sea-floor imagery is greatly facilitated by image processing. Image processing of the digital backscatter data involves removal of noise by median filtering, spatial filtering to remove sonar scans of anomalous intensity, across-track corrections to remove beam patterns caused by nonuniform response of the sonar transducers to changes in incident angle, and contrast enhancement by histogram equalization to maximize the available dynamic range. Correct geologic interpretation requires submarine structural fabrics to be displayed in their proper locations and orientations. Geographic projection of sea-floor imagery is achieved by merging the enhanced imagery with the sonar vehicle navigation and correcting for vehicle attitude. Co-registration of bathymetry with sonar imagery introduces sea-floor relief and permits the imagery to be displayed in three-dimensional perspectives, furthering the ability of the marine geologist to infer the processes shaping formerly hidden subsea terrains.

  4. Distributed Access View Integrated Database (DAVID) system

    NASA Technical Reports Server (NTRS)

    Jacobs, Barry E.

    1991-01-01

    The Distributed Access View Integrated Database (DAVID) System, which was adopted by the Astrophysics Division for their Astrophysics Data System, is a solution to the system heterogeneity problem. The heterogeneous components of the Astrophysics problem is outlined. The Library and Library Consortium levels of the DAVID approach are described. The 'books' and 'kits' level is discussed. The Universal Object Typer Management System level is described. The relation of the DAVID project with the Small Business Innovative Research (SBIR) program is explained.

  5. A Star of David catenane

    NASA Astrophysics Data System (ADS)

    Leigh, David A.; Pritchard, Robin G.; Stephens, Alexander J.

    2014-11-01

    We describe the synthesis of a [2]catenane that consists of two triply entwined 114-membered rings, a molecular link. The woven scaffold is a hexameric circular helicate generated by the assembly of six tris(bipyridine) ligands with six iron(II) cations, with the size of the helicate promoted by the use of sulfate counterions. The structure of the ligand extension directs subsequent covalent capture of the catenane by ring-closing olefin metathesis. Confirmation of the Star of David topology (two rings, six crossings) is provided by NMR spectroscopy, mass spectrometry and X-ray crystallography. Extraction of the iron(II) ions with tetrasodium ethylenediaminetetraacetate affords the wholly organic molecular link. The self-assembly of interwoven circular frameworks of controlled size, and their subsequent closure by multiple directed covalent bond-forming reactions, provides a powerful strategy for the synthesis of molecular topologies of ever-increasing complexity.

  6. David Mechanic: Professional Zombie Hunter.

    PubMed

    Hafferty, Frederic W; Tilburt, Jon

    2016-08-01

    Within the fields of medicine and sociology, the descriptor "profession" (along with its brethren: profession, professionalization, and professionalism) has had a rich etymological history, with terms taking on different meanings at different times-sometimes trespassing into shibboleth and jargon. This etymological journey has co-evolved with the career of David Mechanic to whom this issue of the Journal of Health Politics, Policy and Law is devoted. We exploit a provocative metaphor applied to Mechanic's work on the challenges facing medicine as a profession as a playful exegesis on what we call "profession" to excavate an ensconced and encrusted domain of health jargon operating at the tensive interface of society and modern medical work.

  7. David Mechanic: Professional Zombie Hunter.

    PubMed

    Hafferty, Frederic W; Tilburt, Jon

    2016-08-01

    Within the fields of medicine and sociology, the descriptor "profession" (along with its brethren: profession, professionalization, and professionalism) has had a rich etymological history, with terms taking on different meanings at different times-sometimes trespassing into shibboleth and jargon. This etymological journey has co-evolved with the career of David Mechanic to whom this issue of the Journal of Health Politics, Policy and Law is devoted. We exploit a provocative metaphor applied to Mechanic's work on the challenges facing medicine as a profession as a playful exegesis on what we call "profession" to excavate an ensconced and encrusted domain of health jargon operating at the tensive interface of society and modern medical work. PMID:27127250

  8. David Hubel and Torsten Wiesel.

    PubMed

    Hubel, David; Wiesel, Torsten

    2012-07-26

    While attending medical school at McGill, David Hubel developed an interest in the nervous system during the summers he spent at the Montreal Neurological Institute. After heading to the United States in 1954 for a Neurology year at Johns Hopkins, he was drafted by the army and was assigned to the Neuropsychiatry Division at the Walter Reed Hospital, where he began his career in research and did his first recordings from the visual cortex of sleeping and awake cats. In 1958, he moved to the lab of Stephen Kuffler at Johns Hopkins, where he began a long and fruitful collaboration with Torsten Wiesel. Born in Sweden, Torsten Wiesel began his scientific career at the Karolinska Institute, where he received his medical degree in 1954. After spending a year in Carl Gustaf Bernhard's laboratory doing basic neurophysiological research, he moved to the United States to be a postdoctoral fellow with Stephen Kuffler. It was at Johns Hopkins where he met David Hubel in 1958, and they began working together on exploring the receptive field properties of neurons in the visual cortex. Their collaboration continued until the late seventies. Hubel and Wiesel's work provided fundamental insight into information processing in the visual system and laid the foundation for the field of visual neuroscience. They have had many achievements, including--but not limited to--the discovery of orientation selectivity in visual cortex neurons and the characterization of the columnar organization of visual cortex through their discovery of orientation columns and ocular-dominance columns. Their work earned them the Nobel Prize for Physiology or Medicine in 1981, which they shared with Roger Sperry. PMID:22841302

  9. David Hubel and Torsten Wiesel.

    PubMed

    Hubel, David; Wiesel, Torsten

    2012-07-26

    While attending medical school at McGill, David Hubel developed an interest in the nervous system during the summers he spent at the Montreal Neurological Institute. After heading to the United States in 1954 for a Neurology year at Johns Hopkins, he was drafted by the army and was assigned to the Neuropsychiatry Division at the Walter Reed Hospital, where he began his career in research and did his first recordings from the visual cortex of sleeping and awake cats. In 1958, he moved to the lab of Stephen Kuffler at Johns Hopkins, where he began a long and fruitful collaboration with Torsten Wiesel. Born in Sweden, Torsten Wiesel began his scientific career at the Karolinska Institute, where he received his medical degree in 1954. After spending a year in Carl Gustaf Bernhard's laboratory doing basic neurophysiological research, he moved to the United States to be a postdoctoral fellow with Stephen Kuffler. It was at Johns Hopkins where he met David Hubel in 1958, and they began working together on exploring the receptive field properties of neurons in the visual cortex. Their collaboration continued until the late seventies. Hubel and Wiesel's work provided fundamental insight into information processing in the visual system and laid the foundation for the field of visual neuroscience. They have had many achievements, including--but not limited to--the discovery of orientation selectivity in visual cortex neurons and the characterization of the columnar organization of visual cortex through their discovery of orientation columns and ocular-dominance columns. Their work earned them the Nobel Prize for Physiology or Medicine in 1981, which they shared with Roger Sperry.

  10. David L. Harrison: A Work Of Art

    ERIC Educational Resources Information Center

    Raymond, Allen

    2005-01-01

    This article describes poet and writer David L. Harrison. A former School Board Chairman from Springfield, MO, David was responsible for beginning an annual "Teacher Appreciation Banquet" and for launching the "Sky High for Reading" program. The "Sky High for Reading" program encourages children in Springfield to read enough books so that, if…

  11. Short-term stabilization of grape marc through earthworms.

    PubMed

    Gómez-Brandón, María; Lazcano, Cristina; Lores, Marta; Domínguez, Jorge

    2011-03-15

    The winery industry generates vast amounts of organic waste during the various stages of wine production. Among the possible methodological alternatives available for its treatment, vermicomposting is one of the best-known processes for the biological stabilization of solid organic wastes by transforming them into safer and more stabilized materials suitable for application to soil. In this study we carried out a mesocosm experiment to evaluate the effectiveness of the active phase of vermicomposting for the stabilization of grape marc, an enriched lignocellulosic by-product obtained after the grape crushing and pressing stages in wine production. For this we analysed the chemical, biochemical and microbiological properties of the product resulting from this phase, in comparison with those in a control treatment. Earthworm activity reduced the abundance of both bacterial and fungal PLFA biomarkers. Decreases in microbial activity and in protease and cellulase activities were also attributed to the presence of earthworms. The differences in microbial communities were accompanied by a reduction in the labile C pool and the cellulose content. These results indicate that earthworms played a key role in the stabilization of the grape marc in the short-term, via its effects on organic matter decomposition and microbial biomass and activity.

  12. The Application of Microcomputer-Based Local Systems with the MARC AMC Format.

    ERIC Educational Resources Information Center

    Honhart, Frederick L.

    1988-01-01

    Considers the effects of the new MARC AMC (Archival and Manuscripts Control) format when applied to a microcomputer-based local system for archival operations. Development of the MicroMARC:amc system at Michigan State University is described, and the implications of technological changes on such systems are discussed. (MES)

  13. Effects of Korean Red Ginseng marc with aluminum sulfate against pathogen populations in poultry litters

    PubMed Central

    Chung, Tae Ho; Park, Chul; Choi, In Hag

    2015-01-01

    Background The aim of this study was to evaluate the effects of Korean Red Ginseng marc with aluminum sulfate as litter amendments on ammonia, soluble reactive phosphorus, and pathogen populations in poultry litters. Methods Increasing levels of Korean Red Ginseng marc with aluminum sulfate were applied onto the surface of rice hull as a top-dress application; untreated rice hulls served as controls. Results: Treatment with Korean Red Ginseng marc with aluminum sulfate or aluminum sulfate alone resulted in lower litter pH (p < 0.05), as compared with that of the controls. There were some differences (p < 0.05) between treatments with Korean Red Ginseng marc with aluminum sulfate or aluminum sulfate alone and controls at 2–4 wk (not at 1 wk). Ammonia levels reduced on an average by 29%, 30%, and 32% for 10 g, 20 g Korean Red Ginseng marc with aluminum sulfate, and aluminum sulfate alone, respectively, as compared with controls at 4 wk. During the experiment, Korean Red Ginseng marc with aluminum sulfate or aluminum sulfate treatment had an effect (p < 0.05) on soluble reactive phosphorus content, as compared with the controls (not at 4 wk). A decrease in Salmonella enterica and Escherichia coli was observed (p < 0.05) in litter amended with both Korean Red Ginseng marc with aluminum sulfate and aluminum sulfate alone, as compared with the control, except at 1–3 wk for Salmonella enterica and 1 wk and 4 wk for Escherichia coli, respectively. Conclusion The results showed that using Korean Red Ginseng marc with aluminum sulfate (blends), which act as acidifying agents by reducing the pH of the litter, was equally effective as aluminum sulfate in reducing the environmental impact. PMID:26869836

  14. Obituary: David Stanley Evans, 1916-2004

    NASA Astrophysics Data System (ADS)

    Bash, Frank N.

    2005-12-01

    David Stanley Evans died on 14 November 2004 in Austin, Texas. He was a noted observational astronomer whose career was divided between South Africa and Texas. He also used the extensive historical collections at the University of Texas to write several books on the history of astronomy. He was born in Cardiff, Wales on 28 January 1916. David received his BA degree in mathematics in 1937 from Kings College, Cambridge. He became a PhD student at Cambridge Observatory in 1937, and was one of Sir Arthur Eddington's last surviving students. He received his PhD degree in 1941 with a dissertation entitled, "The Formation of the Balmer Series of Hydrogen in Stellar Atmospheres." He was a conscientious objector to war and, thus, spent the war years at Oxford working with physicist Kurt Mendelssohn on medical problems, involving cadavers, relating to the war. During these years, David was scientific editor of "Discovery", and he was editor of "The Observatory". David left England in 1946 in order to take up the position of Second Assistant at the Radcliffe Observatory, Pretoria, South Africa. He and H. Knox Shaw were the entire staff after R. O. Redman left, and they aluminized and installed the mirrors in the 74-inch telescope. His notable scientific contribution was to use lunar occultations to measure stellar angular diameters during the 1950s. He succeeded in determining the angular diameter of Antares and determined that Arcturus was not circular but had an elliptical shape. The elliptical shape was later shown to be an instrumental artifact, but the utility of using lunar occultations to measure stellar diameters and stellar multiplicity was conclusively demonstrated. T. Gold presented David's paper on lunar occultation angular diameters at the January 1953 meeting of the Royal Astronomical Society. For the rest of his life, David resented Gold's remarks, because he felt that he had been ridiculed. By 1953, David Evans was Chief Assistant at the Royal Observatory

  15. Exploring the Living Planet with David Attenborough.

    ERIC Educational Resources Information Center

    Burgess, Jacquelin; Unwin, David

    1984-01-01

    In this interview David Attenborough, the celebrated natural history film maker and writer, talks about his highly successful television series, "The Living Planet." Devoted to the exposition of the world's ecosystems, the film represents a significant example of popular geographic education. (RM)

  16. Reading Pictures: An Interview with David Wiesner

    ERIC Educational Resources Information Center

    Varga-Dobai, Kinga

    2008-01-01

    Two-time Caldecott Honor winner (Free Fall, Sector 7) and three-time Caldecott Medal winner (Tuesday, The Three Pigs, Flotsam), David Wiesner is regarded as one of the most remarkable creators of visual storytelling living today. Wiesner is well known for his innovative and unique subject matter and his sophisticated painting-like illustrations…

  17. Interview with Dr. David H. Kalsbeek

    ERIC Educational Resources Information Center

    Sauter, David M.

    2005-01-01

    David H. Kalsbeek currently is vice president for enrollment management at DePaul University in Chicago, Illinois. In that capacity, he leads the marketing and enrollment development strategies for the nation's largest and fastest-growing Catholic university, enrolling 23,000 students in eight colleges and six campuses throughout the greater…

  18. Another Perspective: An Interview with David Smith

    ERIC Educational Resources Information Center

    Bowman, Ruth A.; Johnson, Kelli

    2005-01-01

    To provide another perspective on evaluation within nonformal settings, "New Directions for Evaluation" recently interviewed David Smith, the coordinator of the Professional Learning to Close the Achievement Gap program for the Kansas City, Kansas, Public Schools, who has extensive background in education and educational research. He formerly held…

  19. A Conversation with...David Satcher.

    ERIC Educational Resources Information Center

    Campbell, Neil A.

    1996-01-01

    David Satcher began his career as a medical geneticist and was appointed director of the Centers for Disease Control and Prevention (CDC) in 1993. In this interview, Dr. Satcher talks about the responsibilities of the CDC and explains how a childhood experience inspired his interest in medicine and his continuing commitment to community service.…

  20. David Baines: Rural Doctor, Lecturer, Dancer.

    ERIC Educational Resources Information Center

    Wisecarver, Charmaine

    1993-01-01

    Discusses the career of David Baines, an American Indian doctor who successfully integrates traditional and modern medicine. Describes problems faced by American Indian doctors, the tremendous amount of work involved in medical training, and problems associated with working in rural areas and trying to straddle two opposing cultures when…

  1. David L. Gutmann (1925-2013).

    PubMed

    Rose, Jon; Huyck, Margaret; Grunes, Jerome

    2014-01-01

    David L. Gutmann, a pioneer in geropsychology and professor emeritus at Northwestern University, died on November 3, 2013, at the age of 88. A student of Bernice Neugarten, Bruno Bettelheim, and Erik Erikson, Gutmann discovered changes in adult psychological development related to parenting styles that held across diverse cultures.

  2. David L. Gutmann (1925-2013).

    PubMed

    Rose, Jon; Huyck, Margaret; Grunes, Jerome

    2014-01-01

    David L. Gutmann, a pioneer in geropsychology and professor emeritus at Northwestern University, died on November 3, 2013, at the age of 88. A student of Bernice Neugarten, Bruno Bettelheim, and Erik Erikson, Gutmann discovered changes in adult psychological development related to parenting styles that held across diverse cultures. PMID:25046720

  3. Family Matters: A Conversation with David Popenoe

    ERIC Educational Resources Information Center

    Iannone, Carol

    2009-01-01

    This article presents an interview with Professor David Popenoe, author of the controversial book "Disturbing the Nest: Family Change and Decline in Modern Societies" (1988). Popenoe heads the National Marriage Project at Rutgers University, where he taught sociology for forty-five years until his recent retirement. Here, Popenoe discusses his…

  4. Speaking Personally--With David Foster

    ERIC Educational Resources Information Center

    American Journal of Distance Education, 2010

    2010-01-01

    David Foster is the founder of Kryterion, an Internet test administration company, and currently serves there as chief scientist and executive vice president. He is the author of numerous articles for industry trade journals and textbooks and sits on the Council for the International Test Commission. In this interview, Foster talks about his…

  5. David Ben-Gurion: A Creative Leader

    ERIC Educational Resources Information Center

    Rosemarin, Shoshana

    2014-01-01

    David Ben-Gurion (1886-1973), the first Prime Minister of Israel, is included in Pasternak's (2001) list of the nine most memorable leaders of the twentieth century. All of them are remembered for the reforms they initiated. Roosevelt (USA), Stalin (Russia), Castro (Cuba), and Thatcher (England) focused on social-economical changes, whereas…

  6. Carbon and nitrogen mineralization in a vineyard soil amended with grape marc vermicompost.

    PubMed

    Paradelo, Remigio; Moldes, Ana Belén; Barral, María Teresa

    2011-11-01

    Vineyard soils in many areas suffer from low organic matter contents, which can be the cause of negative effects such as increasing the risk of erosion, so the use of organic amendments must be considered a good agricultural practice. Even more, if grape marc is recycled as a soil amendment in the vineyards, benefits from a good waste management strategy are also obtained. In the present study, a grape marc from the wine region of Valdeorras (north-west Spain) was used for the production of vermicompost, and this added to a vineyard soil of the same area in a laboratory study. Mixtures of soil and grape marc vermicompost (2 and 4%, dry weight) were incubated for ten weeks at 25°C and the mineralization of C and N studied. The respiration data were fitted to a first-order kinetic model. The rates of grape marc vermicompost which should be added to the vineyard soil in order to maintain the initial levels of organic matter were estimated from the laboratory data, and found to be 1.7 t ha(-1) year(-1) of bulk vermicompost (if the present mean temperature is considered) and 2.1 t ha(-1) year(-1) of bulk vermicompost (if a 2°C increment in temperature is considered), amounts which could be obtained recycling the grape marc produced in the exploitation.

  7. Carbon and nitrogen mineralization in a vineyard soil amended with grape marc vermicompost.

    PubMed

    Paradelo, Remigio; Moldes, Ana Belén; Barral, María Teresa

    2011-11-01

    Vineyard soils in many areas suffer from low organic matter contents, which can be the cause of negative effects such as increasing the risk of erosion, so the use of organic amendments must be considered a good agricultural practice. Even more, if grape marc is recycled as a soil amendment in the vineyards, benefits from a good waste management strategy are also obtained. In the present study, a grape marc from the wine region of Valdeorras (north-west Spain) was used for the production of vermicompost, and this added to a vineyard soil of the same area in a laboratory study. Mixtures of soil and grape marc vermicompost (2 and 4%, dry weight) were incubated for ten weeks at 25°C and the mineralization of C and N studied. The respiration data were fitted to a first-order kinetic model. The rates of grape marc vermicompost which should be added to the vineyard soil in order to maintain the initial levels of organic matter were estimated from the laboratory data, and found to be 1.7 t ha(-1) year(-1) of bulk vermicompost (if the present mean temperature is considered) and 2.1 t ha(-1) year(-1) of bulk vermicompost (if a 2°C increment in temperature is considered), amounts which could be obtained recycling the grape marc produced in the exploitation. PMID:20837558

  8. 76 FR 12971 - David E. Berman: Debarment Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-09

    ... HUMAN SERVICES Food and Drug Administration David E. Berman: Debarment Order AGENCY: Food and Drug... the Federal Food, Drug, and Cosmetic Act (the FD&C Act) debarring David E. Berman, MD, for 3 years... 1410.35), finds that David E. Berman has been convicted of a misdemeanor under Federal law for...

  9. Interface between astrophysical datasets and distributed database management systems (DAVID)

    NASA Technical Reports Server (NTRS)

    Iyengar, S. S.

    1988-01-01

    This is a status report on the progress of the DAVID (Distributed Access View Integrated Database Management System) project being carried out at Louisiana State University, Baton Rouge, Louisiana. The objective is to implement an interface between Astrophysical datasets and DAVID. Discussed are design details and implementation specifics between DAVID and astrophysical datasets.

  10. 77 FR 26765 - David H.M. Phelps: Debarment Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ... HUMAN SERVICES Food and Drug Administration David H.M. Phelps: Debarment Order AGENCY: Food and Drug... under the Federal Food, Drug, and Cosmetic Act (FD&C Act) debarring David H.M. Phelps for a period of 20... Manual Guide 1410.35), finds that Mr. David H.M. Phelps has been convicted of 10 felony counts...

  11. Cell wall compounds of red grapes skins and their grape marcs from three different winemaking techniques.

    PubMed

    Apolinar-Valiente, Rafael; Romero-Cascales, Inmaculada; Gómez-Plaza, Encarna; López-Roca, José María; Ros-García, José María

    2015-11-15

    Different winemaking practices are aimed at increasing cell wall degradation to facilitate extraction of valuables molecules into the wine. However, little attention has been paid to the composition of marcs from different cultivars according to the influence of the winemaking procedures. We provide information on skin cell walls from Cabernet Sauvignon, Syrah and Monastrell grapes and examine how different winemaking practices (addition of enzymatic preparation and β-galactosidase separately and dry ice addition) may affect the composition of marc skin cell wall material (CWM). The efficiency of CWM isolation from the grape skin and also its composition is influenced by the cultivar. A similar cultivar influence has been detected on CWM from the marc, being the differences also due to the enological technique. Our results help to increase our knowledge on the degradation of cell walls during vinification, while providing a valuable guideline to upgrade the value of these by-products. PMID:25977002

  12. Translation table for DOE/OSTI - COSATI bibliographic records to MARC format records

    SciTech Connect

    Gursky, K.; Holtkamp, I.; Landenberger, S.; Ostrander, C.; Nook, C.; Shanks, M.; Hall, M.

    1985-11-01

    This report contains the recommendations of the committee for the conversion of data in OSTI fields to MARC fields. It is intended as a tool for OSTI to use in developing software that would enable DOE libraries to download OSTI records into MARC-based systems. Goal is to transfer as complete a set of data for each record as possible. No attempt was made to incorporate changes in the use of numerical tags that OSTI has made over the years. In addition, there are a few OSTI fields generated for internal OSTI use only, or that cannot be transferred into any MARC field in the Books format; these OSTI fields have been designated as ''not converted'' in the table.

  13. Cell wall compounds of red grapes skins and their grape marcs from three different winemaking techniques.

    PubMed

    Apolinar-Valiente, Rafael; Romero-Cascales, Inmaculada; Gómez-Plaza, Encarna; López-Roca, José María; Ros-García, José María

    2015-11-15

    Different winemaking practices are aimed at increasing cell wall degradation to facilitate extraction of valuables molecules into the wine. However, little attention has been paid to the composition of marcs from different cultivars according to the influence of the winemaking procedures. We provide information on skin cell walls from Cabernet Sauvignon, Syrah and Monastrell grapes and examine how different winemaking practices (addition of enzymatic preparation and β-galactosidase separately and dry ice addition) may affect the composition of marc skin cell wall material (CWM). The efficiency of CWM isolation from the grape skin and also its composition is influenced by the cultivar. A similar cultivar influence has been detected on CWM from the marc, being the differences also due to the enological technique. Our results help to increase our knowledge on the degradation of cell walls during vinification, while providing a valuable guideline to upgrade the value of these by-products.

  14. David Alan Walker (1928-2012).

    PubMed

    Edwards, Gerald E; Heber, Ulrich

    2012-06-01

    David Alan Walker, Emeritus Professor of Biology, University of Sheffield, UK and Fellow of the Royal Society, died on February 13, 2012. David had a marvelous 60 year career as a scientist, during which he was a researcher, mentor, valued colleague, and a prolific writer in the field of photosynthesis. His career was marked by creative breakthroughs in isolation and analysis of chloroplast metabolism in vitro and simple but valuable technical advances for measurement of photosynthesis in vivo that remain relevant on a global scale to production of crops and biofuels, as well as plant responses to climate change. We include here personal remembrances by the authors (GEE and UH), and by (in alphabetical order): Zoran Cerovic (France), Bob Furbank (Australia), Geoffrey Hind (USA), John Humby (UK), Agu Laisk (Estonia), Peter Lea (UK), Ross Lilley (Australia), Barry Osmond (Australia), Simon Robinson (Australia) and Charles Stirling (UK). PMID:22638915

  15. Structural Seismic Risk at David City, Panama

    NASA Astrophysics Data System (ADS)

    Camacho, E.; Battlo, J.; Novelo-Casanova, D. A.; Tapia, A.; Lindhom, C.

    2007-12-01

    At the southwest margin of the Isthmus of Panama, the Cocos, Nazca and Panama Microplate join in a triple junction. In this tectonic setting, the Panama Fracture Zone (PFZ) which bounds the Nazca and Cocos plate, subducts in an oblique and shallow manner. This zone is one of the most active seismic areas of Central America. On July 18, 1934, the largest earthquake in Panama in historical times (Ms= 7.7) occurred in its northern region. This event caused extensive damage to towns located in the border of Panama and Costa Rica and during the two subsequent days, six aftershocks with magnitude greater than 6.0 were recorded. David City, with 130,000 inhabitants is the most important urban center in southwestern Panama and lies at the northern end of the PFZ. This city was impacted by the strong destructive earthquakes (Ms>7.0) that took place in 1879 and 1934, both with epicenters located on the northern terminus of the PFZ. In this work, we collected and digitized historical seismograms to measure the centroid moment tensor (CMT) from the main 1934 earthquake. Additionally, we gathered new macroseismic information to create improved and more complete isoseismals maps of the 1879 and 1934 events. We determined the probabilistic seismic hazard for David City using records of historical and recent seismicity and the characteristics of local faults. The hazard computation results are presented as peak iso-acceleration curves for rock/hard soil for a recurrence time of 500 years. An elastic response spectrum was obtained with a uniform exceedance probability of 10% in 50 years with one degree of freedom and 5% of damping. Our results indicate maximum peak ground acceleration (PGA) in downtown David of 3.8 and 4.5 m/s2 with a probability annual exceedance of 0.002 and 0.001, respectively. Structural vulnerability was determined analyzing the quality and construction design of housing, buildings, and critical facilities as well as the type of soil where these structures

  16. Subject Access Points in the MARC Record and Archival Finding Aid: Enough or Too Many?

    ERIC Educational Resources Information Center

    Cox, Elizabeth; Czechowski, Leslie

    2007-01-01

    In this research project, the authors set out to discover the current practice in both the archival and cataloging worlds for usage of access points in descriptive records and to learn how archival descriptive practices fit into long-established library cataloging procedures and practices. A sample of archival finding aids and MARC records at 123…

  17. Integrated extraction and anaerobic digestion process for recovery of nutraceuticals and biogas from pomegranate marcs

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Pomegranate marc (PM), a by-product from pomegranate juice processing, has not been effectively utilized. The objectives of this study were to (1) determine the yields and properties of antioxidants (henceforth referring to total phenolics in terms of tannic acid equivalent) and oil extracted from v...

  18. Mathematics, Art, Research, Collaboration, and Storytelling: The High M.A.R.C.S. Project

    ERIC Educational Resources Information Center

    Reilly, Edel M.; Pagnucci, Gian S.

    2007-01-01

    This article describes a curriculum integration project designed to help students better contextualize their learning: The High M.A.R.C.S. Project linked mathematics, art, research, collaboration, and storytelling. The article explains the project in detail, discusses sample student work from the project, and describes how the project work was…

  19. BIBCON--A General Purpose Software System for MARC-Based Book Catalog Production

    ERIC Educational Resources Information Center

    Gibson, Liz

    1973-01-01

    The BIBCON file management system, designed for use on IBM 360 system equipment, performs two basic functions: (1) it creates MARC structured, bibliographic records from untagged input data; (2) from these records it produces page image output for book catalogs. (7 references) (Author)

  20. Using the MARC Format for Archives and Manuscripts Control to Catalog Published Microfilms of Manuscripts Collections.

    ERIC Educational Resources Information Center

    Hodges, Martha

    1989-01-01

    Discusses the advantages of using the MARC format for Archives and Manuscripts Control (AMC), rather than the format for books, to meet the needs of researchers seeking primary source materials. Topics covered include the history and components of the AMC format and searching the AMC file. (seven notes/references) (CLB)

  1. The Marc Hall Prom Predicament: Queer Individual Rights v. Institutional Church Rights in Canadian Public Education

    ERIC Educational Resources Information Center

    Grace, Andre P.; Wells, Kristopher

    2005-01-01

    In 2002, Marc Hall's principal denied him permission to take his boyfriend to his Catholic high-school prom. In examining the politicization of the ensuing prom predicament, we critique Catholicized education and what we perceive to be the Catholic Church's efforts to privatize queerness as it segregates being religious from being sexual. We…

  2. Margedos: A Marc-Like Format for Genealogy with Provision for Documentation.

    ERIC Educational Resources Information Center

    Lamb, Connie

    The purpose of this project was to create a machine-readable format for genealogical data. The Library of Congress MARC (Machine Readable Cataloging) bibliographic system was used as the pattern in producing the format. Tags and codes were used to uniquely identify the components of the record for computer manipulation. The resultant structure,…

  3. Analysis of Readex's Serial Set MARC Records: Improving the Data for the Library Catalog

    ERIC Educational Resources Information Center

    Draper, Daniel; Lederer, Naomi

    2013-01-01

    Colorado State University Libraries (CSUL) purchased the digitized "United States Congressional Serial Set," 1817-1994 and "American State Papers" (1789-1838) from the Readex Division of NewsBank, Inc. and, once funds and records were available, the accompanying MARC records. The breadth of information found in the "Serial Set" is described, along…

  4. America's foremost early astronomer. [David Rittenhouse

    NASA Technical Reports Server (NTRS)

    Rubincam, David Parry; Rubincam, Milton, II

    1995-01-01

    The life of 18th century astronomer, craftsman, and partriot David Rittenhouse is detailed. As a craftsman, he distinguished himself as one of the foremost builders of clocks. He also built magnetic compasses and surveying instruments. The finest examples of his craftsmanship are considered two orreries, mechanical solar systems. In terms of astronomical observations, his best-known contribution was his observation of the transit of Venus in 1769. Rittenhouse constructed the first diffraction grating. Working as Treasurer of Pennsylvania throughout the Revolution, he became the first director of the Mint in 1792. Astronomical observations in later life included charting the position of Uranus after its discovery.

  5. 3. Historic American Buildings Survey, David Aronow, Photographer circa 1924, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey, David Aronow, Photographer circa 1924, DETAIL OF FRONT ELEVATION SHOWING PROJECTING VERANDA. - Laurelton Hall, Laurel Hollow & Ridge Roads, Oyster Bay, Nassau County, NY

  6. 2. Historic American Buildings Survey, David Aronow, Photographer circa 1924, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey, David Aronow, Photographer circa 1924, FRONT ELEVATION SHOWING BELLTOWER AND PROJECTING VERANDA. - Laurelton Hall, Laurel Hollow & Ridge Roads, Oyster Bay, Nassau County, NY

  7. David Lasser: An American Spaceflight Pioneer

    NASA Astrophysics Data System (ADS)

    Ciancone, Michael L.; Lasser, Amelia

    2002-01-01

    David Lasser was one of the founders of the American Interplanetary Society (later known as the American Rocket Society) and author of the first English-language book (in 1931) on the prospects of human spaceflight. Yet his involvement in the fledgling spaceflight movement was short-lived as he soon moved on to pursue a distinguished career in the cause of workers rights. In lieu of an oral history, the author corresponded with Mr. Lasser on a regular basis in the years before his death in 1996 to gather Mr. Lasser's views on human spaceflight activities as viewed from his unique perspective. This paper will document that correspondence with one of America's original spaceflight pioneers.

  8. David D. Derse, 1949-2009

    PubMed Central

    2009-01-01

    David D. Derse, Ph.D., Head of the Retrovirus Gene Expression Section in the HIV Drug Resistance Program at the National Cancer Institute-Frederick (NCI-Frederick), passed away on October 9, 2009, a scant six weeks after being diagnosed with liver cancer. It was with great sadness that family, friends, and colleagues gathered together for his memorial service on Saturday, October 17, 2009, at the Middletown United Methodist Church in Maryland. As a NCI scientist since 1986, Dave studied the molecular mechanisms of infection and replication of a number of different types of retroviruses. Dave became an internationally known expert on human T cell lymphotrophic viruses type 1 and 2 (HTLV-1 and HTLV-2) and served on the editorial boards of Virology and Retrovirology. His most recent studies focused on the mechanisms of HTLV-1 virion morphogenesis, transmission, and replication. PMID:19951436

  9. David Lasser - An American Spaceflight Pioneer

    NASA Technical Reports Server (NTRS)

    Ciancone, Michael L.; Lasser, Amelia

    2002-01-01

    David Lasser was one of the founders of the American Interplanetary Society (later known as the American Rocket Society) and author of the first English-language book (in 1931) on the use of rockets for human spaceflight. His involvement in the fledgling spaceflight movement was short-lived as he moved on to pursue a distinguished, if turbulent, career in the labor movement. In lieu of an oral history, Mr. Lasser provided his recollections on the pioneering days of rocketry and his thoughts on mankind's destiny in space. This paper provides an overview of Mr. Lasser's life and accomplishments as an American spaceflight visionary, along with a compilation of the information that he graciously provided.

  10. Rainforest pioneer. Millennium trailblazers 3: David Cassell.

    PubMed

    Gilmour, D

    1999-01-01

    The Iwokrama International Centre for Rain Forest Conservation in Guyana is headed by Australian forester David Cassells who is also chairman of the Advisory Group for the World Conservation Union Forest Conservation Program. He states that this program is different from other projects to conserve tropical forests since it focuses on financial sustainability and self-sufficiency. He also plans that the revenue for the center will come from a mixture of eco-forestry with certified logging, ecotourism, sustainable production of non-timber products such as vines and latexes, bioprospecting, and the sale of forest management expertise. He further added that the program's success could change the way people value and use tropical forests.

  11. David Lukens Reasoner (1941-1992)

    NASA Astrophysics Data System (ADS)

    Chappell, Rick

    David Lukens Reasoner, former head of NASA's Ionospheric Physics branch, died on April 21, 1992. Reasoner was born July 1, 1941. He worked tirelessly to expand NASA's Space Physics Division, bringing his deep experience and personal expertise to bear on the challenges of growth.During the magical period of the late 1950s and early 1960s when America turned its eyes toward space and the Moon, David Lukens Reasoner journeyed north from the nearby Texas town of Dickinson to Rice University with an idea of getting involved in exploring the frontiers of space. He pursued a course of study in electrical engineering and received a bachelor's degree in 1963 and a master's degree in 1964. In the early 1960s, the Space Science Department at Rice was formed, and President John Kennedy visited to say that America chose to go to space not because it is easy but because it is hard and because it would require the very best talents of our nation to succeed. Dave Reasoner was one of those talented people. His excellence in electrical engineering and physics, combined with his natural abilities in the laboratory, suited him ideally for building the machines of space. As a student, he built sounding rocket payloads and multiple instruments for satellites and experiment packages that were placed on the Moon by the Apollo astronauts. He completed his doctoral degree in space science in 1968. It was in these early thrilling days of space exploration that I first met Dave, beginning a friendship and collegial relationship that was to last 27 years.

  12. 76 FR 7837 - Magill, David W.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Magill, David W.; Notice of Filing Take notice that on February 4, 2011, David W. Magill submitted for filing, an application for authority to hold interlocking...

  13. Music: Part of the Basics at David Douglas and Salem.

    ERIC Educational Resources Information Center

    Pheasant, Marilyn

    1985-01-01

    This bulletin highlights elements of the music programs in two Oregon school districts--David Douglas School District 40 and Salem School District 24J--that have kept these programs viable in spite of financial constraints. Ingredients for success of the overall music program at David Douglas are first described. Important elements include hiring…

  14. 77 FR 71189 - Falck, David P.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-29

    ... Energy Regulatory Commission Falck, David P.; Notice of Filing Take notice that on November 23, 2012, David P. Falck submitted for filing, an application for authority to hold interlocking positions...-8659. Comment Date: 5:00 p.m. Eastern Time on December 14, 2012. Dated: November 23, 2012. Kimberly...

  15. Third Annual David Derse Memorial Lecture and Award | Poster

    Cancer.gov

    By Anne Arthur, Guest Writer The Third Annual David Derse Memorial Lecture and Award presentation was held on Nov. 18 at NCI at Frederick to honor the outstanding research accomplishments of David Derse, Ph.D., and to stimulate the exchange of innovative ideas that Derse was well known for promoting throughout his scientific career.

  16. Teaching Students about the Environment with Henry David Thoreau

    ERIC Educational Resources Information Center

    Curriculum Review, 2008

    2008-01-01

    "Walden: The Ballad of Thoreau" is a two-act four-character play about the final two days writer Henry David Thoreau spent in his cabin before leaving Walden Pond. Teachers can use this play to teach about preserving the earth to students. This article presents a brief synopsis of the play and a brief biography of Henry David Thoreau.

  17. 75 FR 10244 - Ellsworth, David C.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Ellsworth, David C.; Notice of Filing February 25, 2010. Take notice that on February 12, 2010, David C. Ellsworth filed an informational report for authority to hold...

  18. Vermicomposting grape marc yields high quality organic biofertiliser and bioactive polyphenols.

    PubMed

    Domínguez, Jorge; Martínez-Cordeiro, Hugo; Álvarez-Casas, Marta; Lores, Marta

    2014-12-01

    Grape is the largest fruit crop in the world, and most (80%) of the harvested fruit is used to make wine. The main by-product of the wine industry is called grape marc, which consists of the stalks, skin, pulp and seeds that remain after pressing the grapes. The aim of this study was to evaluate whether grape marc could be processed by vermicomposting on an industrial scale to yield both a high-quality organic, polyphenol-free fertiliser and grape seeds (as a source of bioactive polyphenols). Vermicomposting reduced the biomass of grape marc substantially (by 58%), mainly as a result of the loss of volatile solids. After 2 weeks, the process yielded a nutrient-rich, microbiologically active and stabilised peat-like material that was easily separated from the seeds by sieving. Although the polyphenol content of the seeds was considerably reduced, this disadvantage was outweighed by the ease of separation of the seeds. Separation of the seeds also eliminated the polyphenol-associated phytotoxicity from the vermicompost. The seeds still contained useful amounts of polyphenols, which could be directly extracted for use in the pharmaceutical, cosmetic and food industries. The procedure described is effective, simple and economical, and could easily be scaled up for industrial application. PMID:25349068

  19. Micro-scale energy valorization of grape marcs in winery production plants

    SciTech Connect

    Fabbri, Andrea; Bonifazi, Giuseppe; Serranti, Silvia

    2015-02-15

    Highlights: • BioMethane Potential of grape marcs was investigated. • Grape marcs were characterized to realize a micro-scale energy recovery. • Comparative BMP batch-tests utilizing lab-scale reactors were performed. • Biogas valorization by grape marcs anaerobic digestion at small scale is evaluated. - Abstract: The BiochemicalMethanePotential (BMP) of winery organic waste, with reference to two Italian red and white grapes (i.e. Nero Buono and Greco) by-products was investigated. The study was carried out to verify the possibility to reduce the production impact in a green-waste-management-chain-perspective. The possibility to efficiently utilize wine-related-by-products for energy production at a micro-scale (i.e. small-medium scale winery production plant) was also verified. Results showed as a good correlation can be established between the percentage of COD removal and the biogas production, as the winery can produce, from its waste methanization, about 7800 kW h year{sup −1} electrical and 8900 kW h year{sup −1} thermal. A critical evaluation was performed about the possibility to utilize the proposed approach to realize an optimal biomass waste management and an energetic valorization in a local-energy-production-perspective.

  20. Outlining a selection procedure for Saccharomyces cerevisiae isolated from grape marc to improve fermentation process and distillate quality.

    PubMed

    Bovo, Barbara; Carlot, Milena; Fontana, Federico; Lombardi, Angiolella; Soligo, Stefano; Giacomini, Alessio; Corich, Viviana

    2015-04-01

    Nowadays grape marc represents one of the main by-product of winemaking. Many South Europe countries valorize this ligno-cellulosic waste through fermentation and distillation for industrial alcoholic beverage production. The storage of marcs is a crucial phase in the distillation process, due to the physicochemical transformations ascribed to microbial activity. Among the methods adopted by distillers to improve the quality of spirits, the use of selected yeasts has not been explored so far, therefore in this work we evaluated the selection criteria of Saccharomyces cerevisiae strains for grape marc fermentation. The proposed selection procedure included three steps: characterization of phenotypical traits, evaluation of selected strains on pasteurised grape marc at lab-scale (100 g) and pilot-scale fermentation (350 kg). This selection process was applied on 104 strains isolated from grape marcs of different origins and technological treatment. Among physiological traits, β-glucosidase activity level as quality trait seems to be only partially involved in increasing varietal flavour. More effective in describing yeast impact on distillate quality is the ratio higher alcohols/esters that indicates strain ability to increase positive flavours. Finally, evaluating grape marc as source of selected yeasts, industrial treatment rather than varietal origin seems to shape strain technological and quality traits. PMID:25475330

  1. Obituary: David L. Band (1957-2009)

    NASA Astrophysics Data System (ADS)

    Cominsky, Lynn

    2011-12-01

    David L. Band, of Potomac Maryland, died on March 16, 2009 succumbing to a long battle with spinal cord cancer. His death at the age of 52 came as a shock to his many friends and colleagues in the physics and astronomy community. Band showed an early interest and exceptional aptitude for physics, leading to his acceptance at the Massachusetts Institute of Technology as an undergraduate student in 1975. After graduating from MIT with an undergraduate degree in Physics, Band continued as a graduate student in Physics at Harvard University. His emerging interest in Astrophysics led him to the Astronomy Department at the Harvard Smithsonian Center for Astrophysics (CfA), where he did his dissertation work with Jonathan Grindlay. His dissertation (1985) entitled "Non-thermal Radiation Mechanisms and Processes in SS433 and Active Galactic Nuclei" was "pioneering work on the physics of jets arising from black holes and models for their emission, including self-absorption, which previewed much to come, and even David's own later work on Gamma-ray Bursts," according to Grindlay who remained a personal friend and colleague of Band's. Following graduate school, Band held postdoctoral positions at the Lawrence Livermore Laboratory, the University of California at Berkeley and the Center for Astronomy and Space Sciences at the University of California San Diego where he worked on the BATSE experiment that was part of the Compton Gamma Ray Observatory (CGRO), launched in 1991. BATSE had as its main objective the study of cosmic gamma-ray bursts (GRBs) and made significant advances in this area of research. Band became a world-renowned figure in the emerging field of GRB studies. He is best known for his widely-used analytic form of gamma-ray burst spectra known as the "Band Function." After the CGRO mission ended, Band moved to the Los Alamos National Laboratory where he worked mainly on classified research but continued to work on GRB energetics and spectra. When NASA planned

  2. Second Annual David Derse Memorial Lecture and Award | Poster

    Cancer.gov

    By Anne Arthur, Guest Writer The Second Annual David Derse Memorial Lecture and Award presentation was held on November 12, 2013, at the NCI at Frederick Conference Center to honor David Derse’s outstanding research accomplishments and to stimulate the exchange of innovative ideas that Derse was well known for promoting throughout his scientific career. The Annual David Derse Memorial Lecture and Award is sponsored by the HIV Drug Resistance Program, with support from Hye Kyung Chung-Derse, Ph.D., the National Cancer Institute (NCI), the Foundation for the National Institutes of Health (NIH), and colleagues and friends of Derse who contributed to the memorial fund in his honor.

  3. 8. Historic American Buildings Survey, David Aronow, Photographer circa 1924, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Historic American Buildings Survey, David Aronow, Photographer circa 1924, LIVING ROOM WITH TIFFANY STAINED GLASS WINDOWS INCLUDING 'FEEDING THE FLAMINGOES,' 'THE FOUR SEASONS,' AND 'THE BATHERS'. - Laurelton Hall, Laurel Hollow & Ridge Roads, Oyster Bay, Nassau County, NY

  4. 11. Historic American Buildings Survey David J. Kaminsky, Photographer August ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Historic American Buildings Survey David J. Kaminsky, Photographer August 1978 EAST FACADE, PART OF NORTH FACADE, SOUTH DAIRY BARN IN BACKGROUND, WITH FIELD IN FOREGROUND - Longview Farm, North Dairy Barn, Longview Road, Lees Summit, Jackson County, MO

  5. 12. Historic American Buildings Survey David J. Kaminsky, Photographer August ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Historic American Buildings Survey David J. Kaminsky, Photographer August 1978 EAST FACADE, PART OF NORTH FACADE, SOUTH DAIRY BARN IN BACKGROUND - Longview Farm, North Dairy Barn, Longview Road, Lees Summit, Jackson County, MO

  6. Interview With the 2002 Caldecott Medal Winner, David Wiesner.

    ERIC Educational Resources Information Center

    Giorgis, Cyndi; Johnson, Nancy J.

    2003-01-01

    Discusses David Wiesner, the 2002 Caldecott Medal Winner, and includes excerpts of an interview with him. Notes that Wiesner's books appeal to the imagination and often use art elements such as scale. Details the winning book, "The Three Pigs." (PM)

  7. 5. Historic American Buildings Survey, David Aronow, Photographer circa 1924, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey, David Aronow, Photographer circa 1924, DETAIL OF ENTRANCE AND BELLTOWER ON FRONT ELEVATION. - Laurelton Hall, Laurel Hollow & Ridge Roads, Oyster Bay, Nassau County, NY

  8. 19. Historic American Buildings Survey, David Aronow, Photographer circa 1924, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. Historic American Buildings Survey, David Aronow, Photographer circa 1924, INTERIOR OF TIFFANY CHAPEL SHOWING STAINED GLASS WINDOW. - Laurelton Hall, Laurel Hollow & Ridge Roads, Oyster Bay, Nassau County, NY

  9. 12. Historic American Buildings Survey, David Aronow, Photographer circa 1924, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Historic American Buildings Survey, David Aronow, Photographer circa 1924, VIEW OF THE CENTRAL COURT WITH THE FOUNTAIN AND TIFFANY VASES IN NICHES. - Laurelton Hall, Laurel Hollow & Ridge Roads, Oyster Bay, Nassau County, NY

  10. 16. Historic American Buildings Survey, David Aronow, Photographer circa 1924, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Historic American Buildings Survey, David Aronow, Photographer circa 1924, TERRACE OVERLOOKING COLD SPRING HARBOR WITH VIEW OF 'TIFFANY TOWER'. - Laurelton Hall, Laurel Hollow & Ridge Roads, Oyster Bay, Nassau County, NY

  11. 7. Historic American Buildings Survey, David Aronow, Photographer circa 1924, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey, David Aronow, Photographer circa 1924, DETAIL OF MAIN ENTRANCE WITH COLD SPRING HARBOR IN BACKGROUND. - Laurelton Hall, Laurel Hollow & Ridge Roads, Oyster Bay, Nassau County, NY

  12. 11. Historic American Buildings Survey, David Aronow, Photographer circa 1924, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Historic American Buildings Survey, David Aronow, Photographer circa 1924, CENTRAL COURT WITH PORTRAIT OF TIFFANY BY SOROLLA. - Laurelton Hall, Laurel Hollow & Ridge Roads, Oyster Bay, Nassau County, NY

  13. 20. Historic American Buildings Survey, David Aronow, Photographer circa 1924, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Historic American Buildings Survey, David Aronow, Photographer circa 1924, 'THE SPRING' ONE OF SEVEN FOUNTAINS ON TIFFANY ESTATE. - Laurelton Hall, Laurel Hollow & Ridge Roads, Oyster Bay, Nassau County, NY

  14. 9. Historic American Buildings Survey, David Aronow, Photographer circa 1924, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Historic American Buildings Survey, David Aronow, Photographer circa 1924, LIVING ROOM SHOWING LIGHTING FIXTURES OF TIFFANY'S DESIGN. - Laurelton Hall, Laurel Hollow & Ridge Roads, Oyster Bay, Nassau County, NY

  15. 8. Historic American Buildings Survey David J. Kaminsky, Photographer August ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Historic American Buildings Survey David J. Kaminsky, Photographer August 1978 INTERIOR LOOKING SOUTH AT HEARTH - Longview Farm, Paint-Carpentry-Blacksmith Shop, Longview Road, Lees Summit, Jackson County, MO

  16. 1. Historic American Buildings Survey David von Riesen, Photographer July ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey David von Riesen, Photographer July 1965 BARRACKS (West), Left - BARRACKS (East), Right (Combined into New Barn) - Fort Larned, Barracks (West), Larned, Pawnee County, KS

  17. 1. Historic American Buildings Survey David von Riesen, Photographer July ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey David von Riesen, Photographer July 1965 BARRACKS (West), Left - BARRACKS (East), Right (Combined into New Barn) - Fort Larned, Barracks (East), Larned, Pawnee County, KS

  18. mARC Treatment of Hypopharynx Carcinoma with Flat and Flattening-Filter-Free Beam Energies – A Planning Study

    PubMed Central

    Bell, Katharina; Fleckenstein, Jochen; Nuesken, Frank; Licht, Norbert; Rübe, Christian; Dzierma, Yvonne

    2016-01-01

    Background The recently implemented mARC-rotation-technique is capable to deliver high dose rate bursts. For the case of hypopharynx cancer plans we evaluate whether the mARC can achieve an advantage in treatment time in comparison to IMRT. These plans consider two arcs with flat and flattening filter free (FFF) beam energies. Materials and Methods For 8 hypopharynx-cancer patients step-and-shoot-IMRT and mARC plans were created retrospectively using flat and FFF beam energy. The comparison of the plan scenarios considered measures of quality for PTV coverage and sparing of organs at risk. All plans were irradiated on an anthromorphic phantom equipped with thermoluminescent dosimeters to measure scattered dose and treatment times. Results A visual comparison of the dose distribution did not show a marked preference for either technique or energy. The statistical evaluation yielded significant differences in favor of the mARC technique and the FFF energy. Scattered dose could be decreased markedly by the use of the mARC technique. Treatment times could be reduced up to 3 minutes with the use of mARC in comparison to IMRT. The high dose rate energy results in another time advantage of about 1 minute. Conclusions All four plan scenarios yielded equally good quality plans. A combination of the mARC technique with FFF 7 MV high dose rate resulted in a decrease of treatment times from about 9 minutes to 5–6 minutes in comparison to 6 MV IMRT. PMID:27741272

  19. F-MARC: promoting the prevention and management of sudden cardiac arrest in football.

    PubMed

    Kramer, Efraim Benjamin; Dvorak, J; Schmied, C; Meyer, T

    2015-05-01

    Sudden cardiac death is the most common cause of unnatural death in football. To prevent and urgently manage sudden cardiac arrest on the football field-of-play, F-MARC (FIFA Medical and Research Centre) has been fully committed to a programme of research, education, standardisation and practical implementation. This strategy has detected football players at medical risk during mandatory precompetition medical assessments. Additionally, FIFA has (1) sponsored internationally accepted guidelines for the interpretation of an athlete's ECG, (2) developed field-of-play-specific protocols for the recognition, response, resuscitation and removal of a football player having sudden cardiac arrest and (3) introduced and distributed the FIFA medical emergency bag which has already resulted in the successful resuscitation of a football player who had a sudden cardiac arrest on the field-of-play. Recently FIFA, in association with the Institute of Sports and Preventive Medicine in Saarbrücken, Germany, established a worldwide Sudden Death Registry with a view to documenting fatal events on the football field-of-play. These activities by F-MARC are testimony to FIFA's continued commitment to minimising sudden cardiac arrest while playing football.

  20. Obituary: David Q. Wark, 1918-2002

    NASA Astrophysics Data System (ADS)

    McMillin, Larry Max

    2003-12-01

    David Q. Wark, a research meteorologist at the National Environmental Satellite, Data, and Information Service of the National Oceanic and Atmospheric Administration (NOAA/NESDIS) and its predecessor organizations for 55 years, died of cancer 30 July 2002. He will be long remembered for his seminal contributions to the weather satellite program. A pioneer in the use of satellite sensors to provide observations of the Earth's environment for application to weather forecasting and atmospheric science, Dr. Wark was noted for his brilliant insights, dedication, and exceptional scientific achievements. He developed many of the theoretical and experimental techniques on which NOAA's current multi- billion-dollar meteorological satellite program is based. In the 1960's and early 1970's, he and his NOAA colleague Donald Hilleary were the motivating force and principal investigators for the first satellite instruments dedicated to sounding the atmosphere for temperature and water-vapor. These instruments included the Satellite Infra-Red Spectrometer (SIRS)-A and -B and the Vertical Temperature Profile Radiometer (VTPR), which were flown on NASA's Nimbus satellites and NOAA's ITOS-D satellites, respectively. With colleague Henry Fleming, he formulated the radiative transfer equation that quantifies the spectral radiances of the Earth and its atmosphere (measured at satellite altitude) and inverted that equation mathematically to infer the atmospheric temperature profile from satellite-based measurements of those radiances. A difficulty they had to overcome was that the mathematical problem is ill-posed, i.e., it admits of an infinite number of solutions. They arrived at a unique solution via an innovative application of a-priori information on the atmospheric state. This work was described in the landmark 1965 Wark and Fleming paper in the American Meteorological Society's Monthly Weather Review. From that early period until just weeks before his death, Dr. Wark continued

  1. Obituary: David Q. Wark, 1918-2002

    NASA Astrophysics Data System (ADS)

    McMillin, Larry Max

    2003-12-01

    David Q. Wark, a research meteorologist at the National Environmental Satellite, Data, and Information Service of the National Oceanic and Atmospheric Administration (NOAA/NESDIS) and its predecessor organizations for 55 years, died of cancer 30 July 2002. He will be long remembered for his seminal contributions to the weather satellite program. A pioneer in the use of satellite sensors to provide observations of the Earth's environment for application to weather forecasting and atmospheric science, Dr. Wark was noted for his brilliant insights, dedication, and exceptional scientific achievements. He developed many of the theoretical and experimental techniques on which NOAA's current multi- billion-dollar meteorological satellite program is based. In the 1960's and early 1970's, he and his NOAA colleague Donald Hilleary were the motivating force and principal investigators for the first satellite instruments dedicated to sounding the atmosphere for temperature and water-vapor. These instruments included the Satellite Infra-Red Spectrometer (SIRS)-A and -B and the Vertical Temperature Profile Radiometer (VTPR), which were flown on NASA's Nimbus satellites and NOAA's ITOS-D satellites, respectively. With colleague Henry Fleming, he formulated the radiative transfer equation that quantifies the spectral radiances of the Earth and its atmosphere (measured at satellite altitude) and inverted that equation mathematically to infer the atmospheric temperature profile from satellite-based measurements of those radiances. A difficulty they had to overcome was that the mathematical problem is ill-posed, i.e., it admits of an infinite number of solutions. They arrived at a unique solution via an innovative application of a-priori information on the atmospheric state. This work was described in the landmark 1965 Wark and Fleming paper in the American Meteorological Society's Monthly Weather Review. From that early period until just weeks before his death, Dr. Wark continued

  2. Obituary: David Fulmer Bender, 1913-2004

    NASA Astrophysics Data System (ADS)

    Miller, Sylvia L.

    2004-12-01

    David Fulmer Bender died in San Diego, California, on 13 September 2004, at the age of 91. His heart stopped suddenly while he was dancing. His pioneering work in establishing comprehensive, computer-accessible ephemerides of asteroids and comets found many applications, including the first-ever visit to an asteroid, Gaspra, by an interplanetary spacecraft. Dave was born in Reno, Nevada, on 10 February 1913, to Homer Charles Bender and Susan Bowers Bender. The family moved to Spokane, Washington, while Dave was very young. His father was a civil engineer and a graduate of MIT, who helped design bridges and dams throughout the Northwest, including the Grand Coolie Dam. Dave had a brother, Phillip (now deceased), who was one year younger. Advancing rapidly in the Spokane school system, Dave finished high school when he was 15 years old. At 16 he moved to Pasadena, California, and began his studies at the California Institute of Technology (Caltech). In addition to pursuing his course work, he was active in track and football, a tendency toward physical exercise that stayed with him for the rest of his life. It was probably during these years that Dave heard a lecture by Albert Einstein, as mentioned to colleagues many years later. Dave received a BS degree in physics in 1933, an MS in 1934, and a PhD in 1937, all from Caltech. His dissertation was entitled, "The Index of Refraction of Air in the Photographic Infrared." During his sophomore year he found his way to Pomona College in Claremont, California, where he met his future wife, Elizabeth Boyden at a social gathering. They were married in 1935. Dave's academic career spanned the years from 1937 to 1970, initially at Louisiana State University, Vanderbilt University, and then Fisk. As a life-long pacifist and conscientious objector, Dave served alternate duty during World War II. In 1946 he joined the faculty of the physics department at Whittier College in California, where he became the department chair and

  3. INTRODUCTION: David Sherrington as a mentor of young scientists

    NASA Astrophysics Data System (ADS)

    Goldbart, Paul M.

    2008-08-01

    How deeply honoured I am to have the opportunity to express my thoughts at this delightful celebration of David's achievements, so far, in his remarkable career. I have been asked to center my remarks on David's contributions to the mentoring and professional development of scientists early in their careers. This is a topic that I am more than happy to reflect on, because it gives me the opportunity to recall the exciting period I spent as one of David's postgraduate students at Imperial College in the early 1980s. It also gives me the chance to publicly express my gratitude to David for the opportunities he created for me at that time, as well as for the interest and care he has shown in my career and well-being ever since, as we have met up and exchanged news and ideas around the world: in New Mexico and Colorado, in Cancun, Paris and Trieste, at numerous March Meetings of the American Physical Society and, of course in London, Oxford, and my home town, Champaign-Urbana, location of the University of Illinois. I have been a member of David's circle for 25 years now, and I would like to tell you a little about how this came to be. Not because of what this says about me, but, rather, because of what it tells you about David and the rich generosity of his spirit and effort when it comes to supporting the underdog. I was indeed one such underdog—and that's putting it charitably—when I first met David in September of 1982, not long before the academic year was to begin. I had heard about the exciting circle of physical and mathematical ideas swirling around the spin glass question during the previous year, which I had spent at the University of California's Los Angeles campus, through an opportunity kindly arranged, as it happens, by Sam Edwards. But I was eager to return to the UK for postgraduate studies and to work on spin glasses, so I simply showed up at David's Imperial College office, unannounced (if I remember correctly). And with his characteristic

  4. Treatise on insanity in pregnant, postpartum, and lactating women (1858) by Louis-Victor Marcé: a commentary.

    PubMed

    Trede, Katharina; Baldessarini, Ross J; Viguera, Adele C; Bottero, Alain

    2009-01-01

    Louis-Victor Marcé, MD, of Paris compiled an extensive monograph published in 1858 that surveyed knowledge of psychiatric disorders of women during and following pregnancy. This work has largely been ignored for 150 years. We summarize here what is known about Marcé's life and work, and include selected passages from his monograph. Marcé provides extensive clinical descriptions of syndromes, with 79 case examples, and summarizes etiological theories and treatments characteristic of his era and place. This work was based on cases that he personally evaluated and on other reported cases, all drawn from broad social and economic backgrounds. Marcé shows an appreciation of epidemiological evidence and a critical approach to then conventional pathophysiological and therapeutic views. His work anticipated modern rediscovery of the high risk of depression in pregnancy and of both acute mood disorders and psychoses, postpartum. This comprehensive summary of clinical knowledge of perinatal psychiatric disorders of women is a landmark early contribution to a field that has only recently emerged as a psychiatric subspecialty.

  5. Obituary: David Fulmer Bender, 1913-2004

    NASA Astrophysics Data System (ADS)

    Miller, Sylvia L.

    2004-12-01

    David Fulmer Bender died in San Diego, California, on 13 September 2004, at the age of 91. His heart stopped suddenly while he was dancing. His pioneering work in establishing comprehensive, computer-accessible ephemerides of asteroids and comets found many applications, including the first-ever visit to an asteroid, Gaspra, by an interplanetary spacecraft. Dave was born in Reno, Nevada, on 10 February 1913, to Homer Charles Bender and Susan Bowers Bender. The family moved to Spokane, Washington, while Dave was very young. His father was a civil engineer and a graduate of MIT, who helped design bridges and dams throughout the Northwest, including the Grand Coolie Dam. Dave had a brother, Phillip (now deceased), who was one year younger. Advancing rapidly in the Spokane school system, Dave finished high school when he was 15 years old. At 16 he moved to Pasadena, California, and began his studies at the California Institute of Technology (Caltech). In addition to pursuing his course work, he was active in track and football, a tendency toward physical exercise that stayed with him for the rest of his life. It was probably during these years that Dave heard a lecture by Albert Einstein, as mentioned to colleagues many years later. Dave received a BS degree in physics in 1933, an MS in 1934, and a PhD in 1937, all from Caltech. His dissertation was entitled, "The Index of Refraction of Air in the Photographic Infrared." During his sophomore year he found his way to Pomona College in Claremont, California, where he met his future wife, Elizabeth Boyden at a social gathering. They were married in 1935. Dave's academic career spanned the years from 1937 to 1970, initially at Louisiana State University, Vanderbilt University, and then Fisk. As a life-long pacifist and conscientious objector, Dave served alternate duty during World War II. In 1946 he joined the faculty of the physics department at Whittier College in California, where he became the department chair and

  6. SeaMARC 2 side-scan images of submarine volcanoes: Potential analogues for Venus

    NASA Technical Reports Server (NTRS)

    Fryer, P.; Hussong, D.; Mouginis-Mark, P. J.

    1984-01-01

    The Earth's surface beneath the oceans may be very similar, in terms of ambient pressures, to the surface of Venus. For that reason it is particularly important for geologists studying the surface of Venus to understand the processes which form features on the floors of the oceans. With the SeaMARC 2 seafloor mapping system, it is possible to view a swath of seafloor that is 10 km wide (about 6.2 mi). Side scan images of the Mariana region show that volcanoes of the island arc are more complicated than previously realized and that features of the fore-arc region, which resemble volcanoes morphologically, may result from processes other than volcanism. By comparing data obtained from the ocean floor with radar images of Venus, the geological evolution of that planet may be more fully understood.

  7. NMR metabolic fingerprinting and chemometrics driven authentication of Greek grape marc spirits.

    PubMed

    Fotakis, Charalambos; Zervou, Maria

    2016-04-01

    NMR metabolomics was used to investigate 57 Greek spirits of four indigenous and four international varieties from Macedonia (tsipouro) and Crete (tsikoudia) to establish their authenticity. The metabolic profile of Romeiko, Malvasia, Xinomavro, Sangiovese and Nebbiolo varieties was assessed for the first time. The WET1D sequence was used to improve sensitivity and unveil minor metabolites. PCA was applied to delineate the provenance of samples and associate metabolites with distinct varietal characteristics, such as the acidity of Sangiovese, the overripe grapes harvesting of Romeiko, the intense body of Cabernet Sauvignon, the light body of Xinomavro and the glutamic acid for Malvasia. The migration of Cabernet Sauvignon from north Greece to Crete was framed. Monitoring multi-varietal spirits introduced 2-vinylethanol as a marker for yeast selection. OPLS-DA was applied to samples from the same vineyard, thus highlighting genotypic markers. Consequently, the findings address the concepts of typicity and traceability in grape marc spirits. PMID:26593552

  8. INTRODUCTION: David Sherrington as a mentor of young scientists

    NASA Astrophysics Data System (ADS)

    Goldbart, Paul M.

    2008-08-01

    How deeply honoured I am to have the opportunity to express my thoughts at this delightful celebration of David's achievements, so far, in his remarkable career. I have been asked to center my remarks on David's contributions to the mentoring and professional development of scientists early in their careers. This is a topic that I am more than happy to reflect on, because it gives me the opportunity to recall the exciting period I spent as one of David's postgraduate students at Imperial College in the early 1980s. It also gives me the chance to publicly express my gratitude to David for the opportunities he created for me at that time, as well as for the interest and care he has shown in my career and well-being ever since, as we have met up and exchanged news and ideas around the world: in New Mexico and Colorado, in Cancun, Paris and Trieste, at numerous March Meetings of the American Physical Society and, of course in London, Oxford, and my home town, Champaign-Urbana, location of the University of Illinois. I have been a member of David's circle for 25 years now, and I would like to tell you a little about how this came to be. Not because of what this says about me, but, rather, because of what it tells you about David and the rich generosity of his spirit and effort when it comes to supporting the underdog. I was indeed one such underdog—and that's putting it charitably—when I first met David in September of 1982, not long before the academic year was to begin. I had heard about the exciting circle of physical and mathematical ideas swirling around the spin glass question during the previous year, which I had spent at the University of California's Los Angeles campus, through an opportunity kindly arranged, as it happens, by Sam Edwards. But I was eager to return to the UK for postgraduate studies and to work on spin glasses, so I simply showed up at David's Imperial College office, unannounced (if I remember correctly). And with his characteristic

  9. Improved retention of imidacloprid (Confidor) in soils by adding vermicompost from spent grape marc.

    PubMed

    Fernández-Bayo, Jesús D; Nogales, Rogelio; Romero, Esperanza

    2007-05-25

    Batch sorption experiments of the insecticide imidacloprid by ten widely different Spanish soils were carried out. The sorption was studied for the active ingredient and its registered formulation Confidor. The temperature effect was studied at 15 degrees C and 25 degrees C. The addition of a vermicompost from spent grape marc (natural and ground), containing 344 g kg(-1) organic carbon, on the sorption of imidacloprid by two selected soils, a sandy loam and a silty clay loam, having organic carbon content of 3.6 g kg(-1) and 9.3 g kg(-1), respectively, was evaluated. Prior to the addition of this vermicompost, desorption isotherms with both selected soils, were also performed. The apparent hysteresis index (AHI) parameter was used to quantify sorption-desorption hysteresis. Sorption coefficients, K(d) and K(f), for the active ingredient and Confidor(R) in the different soils were similar. Sorption decreased with increasing temperature, this fact has special interest in greenhouse systems. A significant correlation (R(2)=0.965; P<0.01) between K(f) values and the organic carbon (OC) content was found, but some soils showed higher sorption coefficients than that expected from their OC values. The normalized sorption coefficients with the soil organic carbon content (K(oc)) were dispersed and low, implying that other characteristics of soils could contribute to the retention capacity as well. The spent grape marc vermicompost was an effective sorbent of this insecticide (K(f)=149). The sorption of imidacloprid increased significantly in soils amended with this vermicompost. The most pronounced effect was found in the sandy loam soil with low OC content, where the addition of 5% and 10% of vermicompost increased K(f) values by 8- and 15-fold, respectively. Soil desorption of imidacloprid was slower for the soil with the higher OC and clay content.

  10. Dr. David Sawyer, Mickey Mouse and Dr. David Brown attend a ceremony at Ronald McNair Middle School

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. David Sawyer (left), Superintendent of the Brevard County School District, Mickey Mouse, and Dr. David Brown, a NASA astronaut, attend a tribute to NASA astronaut Ronald McNair held in the gymnasium of Ronald McNair Magnet School in Cocoa, Fla. During the tribute, Walt Disney World presented a portrait of McNair to the school, which had previously been renamed for the fallen astronaut. McNair was one of a crew of seven who lost their lives during an accident following launch of the Space Shuttle Challenger in January 1986.

  11. Instructional Implications of David C. Geary's Evolutionary Educational Psychology

    ERIC Educational Resources Information Center

    Sweller, John

    2008-01-01

    David C. Geary's thesis has the potential to alter our understanding of those aspects of human cognition relevant to instruction. His distinction between biologically primary knowledge that we have evolved to acquire and biologically secondary knowledge that is culturally important, taught in educational institutions and which we have not evolved…

  12. Astronaut David Wolf in medical experiment in SLS-2

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Astronaut David A. Wolf, mission specialist, participates in an experiment that investigates in-space distribution and movement of blood and gas in the pulmonary system. The data gathered during the two-week flight will be compared with results of tests performed on Earth to determine the changes that occur in pulmonary functions.

  13. Q & A with Ed Tech Leaders: Interview with David Dockterman

    ERIC Educational Resources Information Center

    Shaughnessy, Michael F.

    2014-01-01

    In this article, Michael F. Shaughnessy, Contributing Editor of this journal, interviews David Dockterman, Chief Architect, Learning Sciences, at Scholastic Education, where he provides guidance on turning research into practical programs. Dockterman was one of the founders of Tom Snyder Productions, a leading educational software developer and…

  14. Battling Creaticide: An Interview with David C. Berliner

    ERIC Educational Resources Information Center

    Ambrose, Don

    2012-01-01

    This article presents an interview with David C. Berliner, a Regents' Professor in the College of Education at Arizona State University. His books include "Educational Psychology," "The Manufactured Crisis," and "The Handbook of Educational Psychology." He has served as president of the American Educational Research Association and of the…

  15. Can Education Save the World? A Response to David Gruenewald

    ERIC Educational Resources Information Center

    Stables, Andrew

    2004-01-01

    Any commitment to education for sustainability assumes that teaching and learning can reduce or prevent damage to the biosphere. However, such an assumption remains deeply problematic. David Gruenewald's is only one of several possible epistemological positions. This article discusses the variety of such positions, arguing for that which might…

  16. Challenging Texts: Teaching Deliberately--Reading Henry David Thoreau's "Walden"

    ERIC Educational Resources Information Center

    Davis, Andrea

    2011-01-01

    One of the more difficult 19th-century American texts for high school students to read is undoubtedly Henry David Thoreau's "Walden." His erudite allusions, often page-long sentences, and sophisticated sense of the ironic initially leave many students cold. Still, the author encourages them to read amid the din of a cultural cacophony that shouts…

  17. Inside the Classroom of Harvard Law School Professor David Wilkins.

    ERIC Educational Resources Information Center

    Lawrence-Lightfoot, Sara

    1999-01-01

    Examines the teaching methods of David Wilkins, an African American Harvard Law School professor considered an exciting teacher by his students and colleagues. Describes his skill in getting students to attend class, engage in legal thinking, feel comfortable in the classroom, and learn the formal rituals and procedures for the court. (SM)

  18. Empowering Adolescent Readers: Intertextuality in Three Novels by David Almond

    ERIC Educational Resources Information Center

    Latham, Don

    2008-01-01

    In "Skellig," "Kit's Wilderness," and "Clay", David Almond employs various types of intertextuality to enrich his narratives. Through the use of allusion, adaptation, collage, and mise-en-abyme, he encourages his adolescent readers to seek out precursor texts and to consider the interrelationships between these texts and his own. By so doing, he…

  19. From the Ocean's Flotsam, David Wiesner Imagines a Journey

    ERIC Educational Resources Information Center

    Ward, Barbara A.

    2008-01-01

    David Wiesner's 2007 Caldecott Medal-winning "Flotsam" blends the events of everyday life with the surreal. As he often does in his picture books, Wiesner plays with size and scale, opening "Flotsam" with a full-page illustration of a sand crab and the enormous eye behind it before pulling back on the second page to reveal the creature's actual…

  20. David Almond's "Skellig": "A New Vista of Contemplation"?

    ERIC Educational Resources Information Center

    Stewart, Susan Louise

    2009-01-01

    The debates that have arisen regarding Darwin's theories of evolution and Christian views of creation and their place in education in the United States have frequently been extremely heated, resulting in trials, hearings, and laws. This article provides an overview of some of the disagreements and illustrates how David Almond's British novel,…

  1. David Haynes: Chronicler of the African American Middle Class.

    ERIC Educational Resources Information Center

    Barron, Ronald

    1997-01-01

    Profiles writer David Haynes, and discusses his four novels (an award-winning young adult book and three novels for the adult market). Concludes that Haynes' success as a novelist is due to his characters, a healthy dose of humor, and his realistic depiction of a wide range of African American characters without resorting to sensationalism or…

  2. Grade 1 Students Meet David Wiesner's "Three Pigs."

    ERIC Educational Resources Information Center

    Pantaleo, Sylvia

    2002-01-01

    Describes the oral, written, and visual arts responses of a group of Grade 1 children. Discusses first grade children's understandings of and responses to several Radical Change characteristics and metafictive techniques found in David Wiesner's "The Three Pigs" (2001), the 2002 Randolph Caldecott Medal winner. Explores the nature of the literary…

  3. Video from Panel Discussion with Joseph Fraumeni and David Schottenfeld

    Cancer.gov

    Video footage from Panel Discussion with Joseph Fraumeni and David Schottenfeld on Cancer Epidemiology over the Last Half-Century and Thoughts on the Future. The discussion took place on May 11, 2012, when DCEG hosted Dr. Schottenfeld as a Visiting Scholar.

  4. Moral philosophers are moral experts! A reply to David Archard.

    PubMed

    Gordon, John-Stewart

    2014-05-01

    In his article 'Why Moral Philosophers Are Not and Should Not Be Moral Experts' David Archard attempts to show that his argument from common-sense morality is more convincing than other competing arguments in the debate. I examine his main line of argumentation and eventually refute his main argument in my reply.

  5. Life after Death in Poverty: David Treuer's "Little"

    ERIC Educational Resources Information Center

    Stirrup, David

    2005-01-01

    David Treuer's debut novel, "Little" (1995), is set on a Minnesota reservation, centering around a dilapidated housing tract that its small community of residents call "Poverty." Aptly named both for the condition and background of the housing, this name is the first pointer to the type of multifaceted reading that the novel merits. This essay…

  6. David Hoffman's Law School Lectures, 1822-1833.

    ERIC Educational Resources Information Center

    Shaffer, Thomas L.

    1982-01-01

    The Baltimore lawyer David Hoffman (1784-1854), the father of American legal ethics, was also the first of the systematic American legal educators. The history and operation of his law school, the curriculum, and his effective use of the lecture method are described and discussed. (MSE)

  7. Reflections on the Scholarly Contributions of Professor David H. Jonassen

    ERIC Educational Resources Information Center

    Reeves, Thomas C.; Lee, Chwee Beng; Hung, Woei

    2013-01-01

    The six papers in this special issue of "Computers and Education" honoring Professor David H. Jonassen are diverse in nature. They also reflect differing interpretations of the implications of Jonassen's work for research and development focused on instructional models and the factors influencing instruction as well as the directions for future…

  8. STS-69 Mission Commander David M. Walker in white room

    NASA Technical Reports Server (NTRS)

    1995-01-01

    STS-69 Mission Commander David M. Walker chats with white room closeout crew members Bob Saulnier (left), Regulo Villalobos and closeout crew leader Travis Thompson prior to entering the flight deck of the Space Shuttle Endeavour at Launch Pad 39A.

  9. David Samwell (1751-98): surgeon on the Discovery.

    PubMed

    Morris, J S

    2002-07-01

    David Samwell, born in North Wales, was surgeon on the Discovery during the third and last voyage of Captain James Cook. Samwell wrote a biography of Cook and was a distinguished poet. He also served on several more voyages, retiring from the sea aged 45. PMID:12151677

  10. Henry David Thoreau and Martin Luther King, Jr. Lesson Plan.

    ERIC Educational Resources Information Center

    Powell, Brent

    1995-01-01

    Presents a five-lesson, high school instructional unit on the ideas and activities of Henry David Thoreau and Martin Luther King, Jr. Includes student objectives, step-by-step instructional procedures, and discussion questions. Provides quotations by Thoreau and King. (CFR)

  11. Child Welfare Research and Training: A Response to David Stoesz

    ERIC Educational Resources Information Center

    Smith, Brenda D.; Vandiver, Vikki L.

    2016-01-01

    In this response to David Stoesz' critique, "The Child Welfare Cartel," the authors agree that child welfare research and training must be improved. The authors disagree, however, with Stoesz' critique of social work education, his assessment of the most-needed forms of child welfare research, and his depiction of the goals and…

  12. A new gene mapping resource: Interspecies hybrids between Pere David`s deer (Elaphurus davidianus) and red deer (Cervus elaphus)

    SciTech Connect

    Tate, M.L.; Mathias, H.C.; Penty, J.M.; Hill, D.F.; Fennessy, P.F.; Dodds, K.G.

    1995-03-01

    Three male F{sub 1} hybrids between Pere David`s deer and red deer were mated to red deer to produce 143 backcross calves. The pedigrees are a rare example of a fertile hybrid between evolutionarily divergent species. We examined the use of these families for genetic mapping of evolutionarily conserved (Type I) loci by testing for genetic linkage between five species-specific protein variants and 12 conserved DNA probes. Two probes were homologous, and the remainder syntenic, to the protein coding loci in cattle or humans. Using six restriction enzymes, each DNA probe detected one or more restriction fragments specific to Pere David`s deer. Linkage analyses among the species-specific variants placed the loci into four linkage groups within which linkage between adjacent loci and gene order was supported by a LOD > 3. Southern and protein analysis of LDHA and ALB provided identical segregation data. These linkage groups were consistent with the cattle gene map and provide new information for comparing the gene maps of ruminants, humans and mice. The deer hybrids are an important new resource that can contribute to the comparative analysis of the mammalian genome. 68 refs., 2 figs., 2 tabs.

  13. Evaluation of direct phloroglucinolysis and colorimetric depolymerization assays and their applicability for determining condensed tannins in grape marc.

    PubMed

    Hixson, Josh L; Bindon, Keren A; Smith, Paul A

    2015-11-18

    To determine the optimum methods for determining condensed tannin (CT) content in grape marc, butanol-hydrochloric acid assays and phloroglucinolysis were adapted for use, applied to a range of grape marc types, and the methods compared. Porter's assay (butanol-HCl) was found to give unreliable results due to nonlinear color responses to grape skin and seed tannin concentrations, whereas the modification to include acetone (Grabber's assay) overcame this. Differences between skin and seed tannin responses highlighted the need to adequately select the correct grape tannin standard, and the formation of pH-dependent color was accounted for through acidification of blank samples. For phloroglucinolysis, the inability to remove highly bound tannins from cell wall material was highlighted, although a measure of tannins remaining post-phloroglucinolysis (Grabber's assay) showed a trend with the level of exposure to oxidative storage or processing conditions. The comparison of CT concentrations from phloroglucinolysis and Grabber's assay gave poor correlation coefficients.

  14. Evaluation of direct phloroglucinolysis and colorimetric depolymerization assays and their applicability for determining condensed tannins in grape marc.

    PubMed

    Hixson, Josh L; Bindon, Keren A; Smith, Paul A

    2015-11-18

    To determine the optimum methods for determining condensed tannin (CT) content in grape marc, butanol-hydrochloric acid assays and phloroglucinolysis were adapted for use, applied to a range of grape marc types, and the methods compared. Porter's assay (butanol-HCl) was found to give unreliable results due to nonlinear color responses to grape skin and seed tannin concentrations, whereas the modification to include acetone (Grabber's assay) overcame this. Differences between skin and seed tannin responses highlighted the need to adequately select the correct grape tannin standard, and the formation of pH-dependent color was accounted for through acidification of blank samples. For phloroglucinolysis, the inability to remove highly bound tannins from cell wall material was highlighted, although a measure of tannins remaining post-phloroglucinolysis (Grabber's assay) showed a trend with the level of exposure to oxidative storage or processing conditions. The comparison of CT concentrations from phloroglucinolysis and Grabber's assay gave poor correlation coefficients. PMID:26551987

  15. Magen David Adom--the EMS in Israel.

    PubMed

    Ellis, Daniel Y; Sorene, Eliot

    2008-01-01

    Israel is a small country with a population of around 7 million. The sole EMS provider for Israel is Magen David Adom (MDA) (translated as 'Red Shield of David'). MDA also carries out the functions of a National Society (similar to the Red Cross) and provides all the blood and blood product services for the country. Nationwide, the organisation responds to over 1000 emergency calls a day and uses doctors, paramedics, emergency medical technicians and volunteers. Local geopolitics has meant that MDA has to be prepared for anything from everyday emergency calls to suicide bombings and regional wars. MDA also prides itself in being able to rapidly assemble and dispatch mobile aid teams to scenes of international disasters. Such a broad range of activities is unusual for a single EMS organisation. PMID:17767990

  16. Magen David Adom--the EMS in Israel.

    PubMed

    Ellis, Daniel Y; Sorene, Eliot

    2008-01-01

    Israel is a small country with a population of around 7 million. The sole EMS provider for Israel is Magen David Adom (MDA) (translated as 'Red Shield of David'). MDA also carries out the functions of a National Society (similar to the Red Cross) and provides all the blood and blood product services for the country. Nationwide, the organisation responds to over 1000 emergency calls a day and uses doctors, paramedics, emergency medical technicians and volunteers. Local geopolitics has meant that MDA has to be prepared for anything from everyday emergency calls to suicide bombings and regional wars. MDA also prides itself in being able to rapidly assemble and dispatch mobile aid teams to scenes of international disasters. Such a broad range of activities is unusual for a single EMS organisation.

  17. Kinetic modeling of ultrasound-assisted extraction of phenolic compounds from grape marc: influence of acoustic energy density and temperature.

    PubMed

    Tao, Yang; Zhang, Zhihang; Sun, Da-Wen

    2014-07-01

    The effects of acoustic energy density (6.8-47.4 W/L) and temperature (20-50 °C) on the extraction yields of total phenolics and tartaric esters during ultrasound-assisted extraction from grape marc were investigated in this study. The ultrasound treatment was performed in a 25-kHz ultrasound bath system and the 50% aqueous ethanol was used as the solvent. The initial extraction rate and final extraction yield increased with the increase of acoustic energy density and temperature. The two site kinetic model was used to simulate the kinetics of extraction process and the diffusion model based on the Fick's second law was employed to determine the effective diffusion coefficient of phenolics in grape marc. Both models gave satisfactory quality of data fit. The diffusion process was divided into one fast stage and one slow stage and the diffusion coefficients in both stages were calculated. Within the current experimental range, the diffusion coefficients of total phenolics and tartaric esters for both diffusion stages increased with acoustic energy density. Meanwhile, the rise of temperature also resulted in the increase of diffusion coefficients of phenolics except the diffusion coefficient of total phenolics in the fast stage, the value of which being the highest at 40 °C. Moreover, an empirical equation was suggested to correlate the effective diffusion coefficient of phenolics in grape marc with acoustic energy density and temperature. In addition, the performance comparison of ultrasound-assisted extraction and convention methods demonstrates that ultrasound is an effective and promising technology to extract bioactive substances from grape marc.

  18. STS-86 Mission Specialist David Wolf in white room

    NASA Technical Reports Server (NTRS)

    1997-01-01

    STS-86 Mission Specialist David A. Wolf, at center facing camera, prepares to enter the Space Shuttle Atlantis at Launch Pad 39A, with the assistance of Rick Welty, in foreground at center, United Space Alliance (USA) orbiter vehicle closeout chief; and closeout team members, in background from left, Jim Davis, NASA quality assurance specialist; and George Schramm, USA mechanical technician. STS-86 Mission Specialist Vladimir Georgievich Titov, in foreground at far left, is awaiting his turn.

  19. About David Ruelle, After His 80th Birthday

    NASA Astrophysics Data System (ADS)

    Gallavotti, Giovanni

    2016-05-01

    This is, with minor modifications, a text read at the 114th Statistical Mechanics meeting, in honor of D. Ruelle and Y. Sinai, at Rutgers, Dec. 13-15, 2015. It does not attempt to analyze, or not even just quote, all works of David Ruelle; I discuss, as usual in such occasions, a few among his works with which I have most familiarity and which were a source of inspiration for me.

  20. David Nelson, MD, MPH | Division of Cancer Prevention

    Cancer.gov

    Dr. David E Nelson is the Director of the Cancer Prevention Fellowship Program (CPFP) Branch in the National Cancer Institute's Division of Cancer Prevention. The CPFP is an internationally renowned postdoctoral program designed to train early career scientific researchers and leaders in the field of cancer prevention. Dr. Nelson came to the CPFP in 2008 after working at the Centers for Disease Control and Prevention in Atlanta for many years. |

  1. Survey of the Variation in Grape Marc Condensed Tannin Composition and Concentration and Analysis of Key Compositional Factors.

    PubMed

    Hixson, Josh L; Jacobs, Joe L; Wilkes, Eric N; Smith, Paul A

    2016-09-28

    Grape marc contains a number of compounds with potential antimethanogenic activity in ruminants, including condensed tannins (CTs). Using direct phloroglucinolysis, a survey of CT chemistry across 66 grape marc samples showed diversity in concentration (6.9 to 138.8 g/kg of dry matter). Concentration was found to be independent of CT composition, although all compositional variables were significantly correlated (P < 0.0001). Twenty samples diverse in CT were selected from a cluster analysis and analyzed for compounds relevant to ruminant digestion and methanogenesis, including metabolizable energy (6.6-12.0 MJ/kg DM), crude protein (3.2-14.4% DM), neutral detergent fiber (18.4-61.4% DM), and ethanol soluble carbohydrates (2.0-40.6% DM). Fatty acid concentrations varied throughout the 20 samples (5.2-184.5 g/kg DM), although fatty acid profile showed two distinct groups. Grape marc varies widely in nutritional value, and in compounds that have been linked with changes in ruminant digestion and methane emissions. PMID:27615673

  2. When is an odd number not odd? Influence of task rule on the MARC effect for numeric classification.

    PubMed

    Cho, Yang Seok; Proctor, Robert W

    2007-09-01

    When classifying numbers as odd or even with left-right keypresses, performance is better with the mapping even-right/odd-left than with the opposite mapping. This linguistic markedness association of response codes (MARC) effect has been attributed to compatibility between the linguistic markedness of stimulus and response codes. In 2 experiments participants made keypresses to the Arabic numerals or number words 3, 4, 8, and 9 using the odd-even parity rule or a multiple-of-3 rule, which yield the same keypress response for each stimulus. For both stimulus modes, the MARC effect was obtained with the odd-even rule, but tended to reverse with the multiple-of-3 rule. The reversal was complete for the right response, but task rule had little influence on the left response. The results are consistent with the view that the MARC effect and its reversal are caused by correspondence of the stimulus code designated as positive by the task rule with the positive-polarity right response code.

  3. Improving green waste composting by addition of sugarcane bagasse and exhausted grape marc.

    PubMed

    Zhang, Lu; Sun, Xiangyang

    2016-10-01

    The composting of lignocellulosic waste into compost is a potential way of sustainably disposing of a waste while generating a useful product. The current study determined whether the addition of sugarcane bagasse (SCB) (at 0, 15, and 25%) and/or exhausted grape marc (EGM) (at 0, 10, and 20%) improved the two-stage composting of green waste (GW). The combined addition of SCB and EGM improved composting conditions and the quality of the compost product in terms of temperature, water-holding capacity, particle-size distribution, coarseness index, pH, electrical conductivity, water-extractable organic carbon and nitrogen, microbial numbers, enzymatic activities, polysaccharide and lignin content, nutrient content, respiration, and phytotoxicity. The optimal two-stage composting and the best quality compost were obtained with the combined addition of 15% SCB and 20% EGM. With the optimized two-stage composting method, the compost matured in only 21days rather than in the 90-270days required for traditional composting. PMID:27376832

  4. A Staged Reading of the Play: TRANSCENDENCE: Relativity and Its Discontents by Robert Marc Friedman

    NASA Astrophysics Data System (ADS)

    Friedman, Robert Marc

    2015-04-01

    TRANSCENDENCE explores aspects of Einstein's life and his general theory of relativity at the time of the theory's creation and initial reception. While being faithful to historical scholarship, the play creates its own theatrical reality aiming to engage emotions and intellect. Those who strive for transcendence must nevertheless also confront the harsh realities of living in specific time-bound social contexts. Universal constants that anchor physical theory in an objective reality, as Einstein believed, do not readily have equivalents in notions of identity, duty, loyalty, and excellence. In November 1915 after toiling for years in Zurich, Prague, and now Berlin, Einstein achieved his general theory of relativity. When in 1919 British astronomers announced evidence for the bending of starlight by the sun as Einstein had predicted, he soon surprisingly found himself an international celebrity. Expectations arose that he would be called to Stockholm. But the Nobel Committee for Physics refused to acknowledge ``speculations'' such Einstein's. The dismissal of relativity entailed principled and biased opposition, and not simply mistakes in evaluation. Several committee members agreed that Einstein must not receive a Prize. Join us for a dramatic staged reading of TRANSCENDENCE, a play by the science historian Robert Marc Friedman (http://www.hf.uio.no/iakh/english/people/aca/robertfr/index.html) and directed by James Glossman, Lecturer in Directing and Shakespeare, Johns Hopkins University. After the performance, the playwright, director and actors will be available for a talk-back audience discussion.

  5. SeaMARC II mapping of transform faults in the Cayman Trough, Caribbean Sea

    USGS Publications Warehouse

    Rosencrantz, Eric; Mann, Paul

    1992-01-01

    SeaMARC II maps of the southern wall of the Cayman Trough between Honduras and Jamaica show zones of continuous, well-defined fault lineaments adjacent and parallel to the wall, both to the east and west of the Cayman spreading axis. These lineaments mark the present, active traces of transform faults which intersect the southern end of the spreading axis at a triple junction. The Swan Islands transform fault to the west is dominated by two major lineaments that overlap with right-stepping sense across a large push-up ridge beneath the Swan Islands. The fault zone to the east of the axis, named the Walton fault, is more complex, containing multiple fault strands and a large pull-apart structure. The Walton fault links the spreading axis to Jamaican and Hispaniolan strike-slip faults, and it defines the southern boundary of a microplate composed of the eastern Cayman Trough and western Hispaniola. The presence of this microplate raises questions about the veracity of Caribbean plate velocities based primarily on Cayman Trough opening rates.

  6. Triterpene glycosides from red ginseng marc and their anti-inflammatory activities.

    PubMed

    Chung, Ill-Min; Kim, Young-Ock; Ali, Mohammed; Kim, Seung-Hyun; Park, Inmyoung; Kim, Eun-Hye; Yang, Ye-Sul; Park, Hye-Ran; Son, Eun-Suk; Ahmad, Ateeque

    2014-09-01

    Three new triterpene glycosides ursan-3β,19α,22β-triol-3-O-β-D-glucopyranosyl (2'→1″)-β-D-glucopyranoside (1), ursan-3α,11β-diol-3-O-α-D-glucopyranosyl-(6'→1″)-α-D-glucopyranosyl-(6″→1‴)-α-D-glucopyranosyl-(6‴→1‴')-α-D-glucopyranoside (2) and lanost-5,24-dien-3β-ol-3-O-β-D-glucopyranosyl-(6'→1″)-β-D-glucopyranosyl-(6″→1‴)-β-D-glucopyranoside (3), together with one known compound were isolated and identified from the marc of red ginseng. Their structures were elucidated by spectroscopic data analysis. Compounds (1-3) were investigated for anti-inflammatory effects using the RAW 264.7 macrophage cell line. In the cell proliferation assay, lipopolysaccharide stimulation decreased cell proliferation of RAW 264.7 macrophage cells, but the suppression of cell proliferation was significantly protected by treatment with compounds 2 and 3. Compounds 2 and 3 had a suppressive effect on the production of nitric oxide (NO), and they inhibited mRNA expression of proinflammatory mediators such as inducible nitric oxide synthase, and cyclooxygenase-2, and proinflammatory cytokines such as two interleukins and tumor necrosis factor-α. These findings suggest that compounds 2 and 3 have potential anti-inflammatory activities.

  7. Abner Doubleday, Marc Bloch, and the cultural significance of baseball in rural America.

    PubMed

    Vaught, David

    2011-01-01

    In 1907 baseball's promoters decreed that Civil War hero Abner Doubleday created the game in the village of Cooperstown, New York, in 1839. Baseball thus acquired a distinctly rural American origin and a romantic pastoral appeal. Skeptics have since presented irrefutable evidence that America's pastime was neither born in the United States nor was a product of rural life. But in their zeal to debunk the myth of baseball's rural beginnings, historians have fallen prey to what Annales School founder Marc Bloch famously called the "idol of origins," and all but neglected the very real phenomenon of rural baseball itself. The claim that baseball has always been "a city game for city men" does not stand up to empirical scrutiny anymore than the Doubleday myth itself, as this address demonstrates with three case studies -- Cooperstown in the 1830s, Davisville, California, in the 1880s, and Milroy, Minnesota, in the 1950s. Baseball may have been a source of rural nostalgia for city people, but it was the sport of choice for farmers and a powerful cultural agent.

  8. Improving green waste composting by addition of sugarcane bagasse and exhausted grape marc.

    PubMed

    Zhang, Lu; Sun, Xiangyang

    2016-10-01

    The composting of lignocellulosic waste into compost is a potential way of sustainably disposing of a waste while generating a useful product. The current study determined whether the addition of sugarcane bagasse (SCB) (at 0, 15, and 25%) and/or exhausted grape marc (EGM) (at 0, 10, and 20%) improved the two-stage composting of green waste (GW). The combined addition of SCB and EGM improved composting conditions and the quality of the compost product in terms of temperature, water-holding capacity, particle-size distribution, coarseness index, pH, electrical conductivity, water-extractable organic carbon and nitrogen, microbial numbers, enzymatic activities, polysaccharide and lignin content, nutrient content, respiration, and phytotoxicity. The optimal two-stage composting and the best quality compost were obtained with the combined addition of 15% SCB and 20% EGM. With the optimized two-stage composting method, the compost matured in only 21days rather than in the 90-270days required for traditional composting.

  9. A homosexual militant at the beginning of the century: Marc André Raffalovich.

    PubMed

    Cardon, P

    1993-01-01

    This work is based on my thesis from Aix en Provence on French Civilisation and Letters (1984). The head of the examinations was the writer Raymond Jean. My idea is to show how the decadent writer and poet Marc André Raffalovich fought against the personalities in science concerning homosexuality with a new point of view and with great difficulty, shedding new light on this subject in a review from 1886 to 1914 under the direction of Dr. Alexandre Lacassagne Les Archives d'Anthropologie Criminelle de Médecine Légale et de Psychologie Normale et Pathologique published in 1886, edited by the director A. Lacassagne, professor and chairman of legal medicine, Lyon, and author of the article "Pederastie," Dictionnaire Encyclopedique des Sciences Medicales, volume XXII published in 1886. In 1893, he wrote an introduction for l'Inversion Sexuelle of Dr. Julien Chevalier (Paris: Masson-Lyon Storck). This monthly review "d'au moins 80 pages" was called L'Ecole Lyonnaise, and so to say, l'Ecole Francaise d'Anthropologie Criminelle, which defends against l'Ecole Italienne of Lombroso, the culturalist theory of the birth of the criminal; according to this école du milieu social: "La Société a les criminels qu'elle merite" (The society has criminals it deserves). After the first world war, it was to be overridden by the Marxist analysis. PMID:8301079

  10. Fermented grape marc (FGM): immunomodulating properties and its potential exploitation in the treatment of neurodegenerative diseases.

    PubMed

    Marzulli, G; Magrone, T; Kawaguchi, K; Kumazawa, Y; Jirillo, E

    2012-01-01

    The onset of neurodegenerative diseases has become more frequent than in the past also in relation to inappropriate dietary habits adopted in the western world. Nutraceuticals are currently investigated in order to prevent or retard the outcome of the so-called diet-related diseases, even including neurodegenerative pathologies. Here, we have in vitro studied the ability of fermented grape marc (FGM) from Negroamaro (N) and Koshu (K) Vitis vinifera to modulate the function of human peripheral blood mononuclear cells (PBMCs). Actually, both FGMs were able to increase the release and the intracellular content of inflammatory and anti-inflammatory cytokines, the induction of FoxP3 (a biomarker of T regulatory cells) and reduce the production of Granzyme B from PBMCs. Since these FGM-induced effects tend to polarize the immune response toward an anti-inflammatory pathway, the potential use of FGMs may represent a valid therapeutic measure to mitigating neuroinflammation in pathologies such as Parkinson disease and Alzheimer disease.

  11. Abner Doubleday, Marc Bloch, and the cultural significance of baseball in rural America.

    PubMed

    Vaught, David

    2011-01-01

    In 1907 baseball's promoters decreed that Civil War hero Abner Doubleday created the game in the village of Cooperstown, New York, in 1839. Baseball thus acquired a distinctly rural American origin and a romantic pastoral appeal. Skeptics have since presented irrefutable evidence that America's pastime was neither born in the United States nor was a product of rural life. But in their zeal to debunk the myth of baseball's rural beginnings, historians have fallen prey to what Annales School founder Marc Bloch famously called the "idol of origins," and all but neglected the very real phenomenon of rural baseball itself. The claim that baseball has always been "a city game for city men" does not stand up to empirical scrutiny anymore than the Doubleday myth itself, as this address demonstrates with three case studies -- Cooperstown in the 1830s, Davisville, California, in the 1880s, and Milroy, Minnesota, in the 1950s. Baseball may have been a source of rural nostalgia for city people, but it was the sport of choice for farmers and a powerful cultural agent. PMID:21313784

  12. Hyperspectral Remote Sensing and Ecological Modeling Research and Education at Mid America Remote Sensing Center (MARC): Field and Laboratory Enhancement

    NASA Technical Reports Server (NTRS)

    Cetin, Haluk

    1999-01-01

    The purpose of this project was to establish a new hyperspectral remote sensing laboratory at the Mid-America Remote sensing Center (MARC), dedicated to in situ and laboratory measurements of environmental samples and to the manipulation, analysis, and storage of remotely sensed data for environmental monitoring and research in ecological modeling using hyperspectral remote sensing at MARC, one of three research facilities of the Center of Reservoir Research at Murray State University (MSU), a Kentucky Commonwealth Center of Excellence. The equipment purchased, a FieldSpec FR portable spectroradiometer and peripherals, and ENVI hyperspectral data processing software, allowed MARC to provide hands-on experience, education, and training for the students of the Department of Geosciences in quantitative remote sensing using hyperspectral data, Geographic Information System (GIS), digital image processing (DIP), computer, geological and geophysical mapping; to provide field support to the researchers and students collecting in situ and laboratory measurements of environmental data; to create a spectral library of the cover types and to establish a World Wide Web server to provide the spectral library to other academic, state and Federal institutions. Much of the research will soon be published in scientific journals. A World Wide Web page has been created at the web site of MARC. Results of this project are grouped in two categories, education and research accomplishments. The Principal Investigator (PI) modified remote sensing and DIP courses to introduce students to ii situ field spectra and laboratory remote sensing studies for environmental monitoring in the region by using the new equipment in the courses. The PI collected in situ measurements using the spectroradiometer for the ER-2 mission to Puerto Rico project for the Moderate Resolution Imaging Spectrometer (MODIS) Airborne Simulator (MAS). Currently MARC is mapping water quality in Kentucky Lake and

  13. Evaluation of carbon degradation during co-composting of exhausted grape marc with different biowastes.

    PubMed

    Fernández, F J; Sánchez-Arias, V; Villaseñor, J; Rodríguez, L

    2008-10-01

    In this work the carbon biodegradation of exhausted grape marc (EGM) combined with other organic wastes using the turned pile composting system was studied. Four different piles were made of EGM in Pile 1, EGM mixed with cow manure and straw (CMS) in Pile 2, EGM mixed with municipal solid waste (MSW) in Pile 3 and EGM mixed with grape stalks (GS) in Pile 4. The results obtained were modelled to determine the main kinetic and stoichiometric parameters. Regarding to the rate constants of the composting processes they were increased from 0.033d(-1), the value obtained when EGM was composted alone, to 0.040 and 0.044d(-1) when MSW and GS were added, respectively as co-substrates. However, the addition of CMS reduced the rate constant. About the biodegradable carbon fractions, it was observed that the co-composting reduced significantly the remanent carbon concentration after composting in all the piles whilst increased the readily biodegradable carbon fractions from 35, the value obtained when EGM was composted alone, to 50 and 60%, respectively when MSW or GS were added. As regards the temperature profiles, only Piles 1 and 4 achieved thermal hygienization values and about the nitrogen losses, the lowest percentage of nitrogen loss took place when GS were added, because of its optimum pH and C/N initial ratio. Thus, though any of these wastes could be used for co-composting with EGM, the use of GS as co-substrate and bulking agent for the co-composting process of EGM was recommended.

  14. David Kasner, MD, and the Road to Pars Plana Vitrectomy.

    PubMed

    Blodi, Christopher F

    2016-01-01

    David Kasner, MD (1927-2001), used his extensive dissections of eye bank eyes and experiences in teaching cataract surgery to resident physicians to realize that excision of vitreous when present in the anterior chamber of eyes undergoing cataract surgery was preferable to prior intraoperative procedures. Noting that eyes tolerated his maneuvers, he then performed planned subtotal open-sky vitrectomies; first on a traumatized eye in 1961, then on two eyes of patients with amyloidosis (1966-1967). The success of these operations was noted by others, most particularly Robert Machemer, MD. Kasner's work directly led to further surgical developments, including closed pars plana vitrectomy. PMID:27660504

  15. David Kasner, MD, and the Road to Pars Plana Vitrectomy

    PubMed Central

    Blodi, Christopher F.

    2016-01-01

    David Kasner, MD (1927–2001), used his extensive dissections of eye bank eyes and experiences in teaching cataract surgery to resident physicians to realize that excision of vitreous when present in the anterior chamber of eyes undergoing cataract surgery was preferable to prior intraoperative procedures. Noting that eyes tolerated his maneuvers, he then performed planned subtotal open-sky vitrectomies; first on a traumatized eye in 1961, then on two eyes of patients with amyloidosis (1966–1967). The success of these operations was noted by others, most particularly Robert Machemer, MD. Kasner’s work directly led to further surgical developments, including closed pars plana vitrectomy. PMID:27660504

  16. David Kasner, MD, and the Road to Pars Plana Vitrectomy

    PubMed Central

    Blodi, Christopher F.

    2016-01-01

    David Kasner, MD (1927–2001), used his extensive dissections of eye bank eyes and experiences in teaching cataract surgery to resident physicians to realize that excision of vitreous when present in the anterior chamber of eyes undergoing cataract surgery was preferable to prior intraoperative procedures. Noting that eyes tolerated his maneuvers, he then performed planned subtotal open-sky vitrectomies; first on a traumatized eye in 1961, then on two eyes of patients with amyloidosis (1966–1967). The success of these operations was noted by others, most particularly Robert Machemer, MD. Kasner’s work directly led to further surgical developments, including closed pars plana vitrectomy.

  17. Idealism and romantic patriotism for science - an interview with José Francisco David-Ferreira.

    PubMed

    David-Ferreira, José Francisco

    2009-01-01

    Jose Francisco David-Ferreira is one of the most influential Professors of Cell and Developmental Biology in Portugal. David-Ferreira pioneered the use of electron microscopy in cell biology and experimental embryology. He also paved the way for successive generations of biologists who cross-fertilized the national scientific community. As we discuss briefly below, David-Ferreira is above all a Pedagogue and an Institution builder. PMID:19247950

  18. Attitudes of Mississippi college students toward David Duke before and after seeing the film Who is David Duke?

    PubMed

    Eisenman, R; Girdner, E J; Burroughs, R G; Routman, M

    1993-01-01

    The attitudes of 211 students at a university in Mississippi were investigated both before and after seeing the Public Broadcasting Film Who Is David Duke? The film provided evidence of Duke's current racism, anti-Semitism, and pro-Nazi leanings. In a previous study with university students in Louisiana, the majority did not change their attitudes after watching the film (Eisenman, 1993). However, in the present study, students' attitudes showed change in an anti-Duke direction. The findings are discussed and reasons given for the differences between the two samples, and for the popularity of Duke, a former leader of the Ku Klux Klan.

  19. Attitudes of Mississippi college students toward David Duke before and after seeing the film Who is David Duke?

    PubMed

    Eisenman, R; Girdner, E J; Burroughs, R G; Routman, M

    1993-01-01

    The attitudes of 211 students at a university in Mississippi were investigated both before and after seeing the Public Broadcasting Film Who Is David Duke? The film provided evidence of Duke's current racism, anti-Semitism, and pro-Nazi leanings. In a previous study with university students in Louisiana, the majority did not change their attitudes after watching the film (Eisenman, 1993). However, in the present study, students' attitudes showed change in an anti-Duke direction. The findings are discussed and reasons given for the differences between the two samples, and for the popularity of Duke, a former leader of the Ku Klux Klan. PMID:8237541

  20. First Scholarship at AGU Established by David E. Lumley

    NASA Astrophysics Data System (ADS)

    Tahar, Joanna G.

    2009-09-01

    Shortly after AGU launched its annual voluntary contribution campaign last year—the theme was “Building Tomorrow's Talent Today”—the Union's development office received an e-mail message from David E. Lumley about establishing a scholarship for a high-school student or undergraduate. Many scientific societies and associations have quite a few named scholarships, but for AGU this was a new concept. Lumley was sure of what he wanted to do and even more excited when he learned that his scholarship would be a first for AGU. “I want to help inspire today's young minds to work on problems of global importance in both the energy and environment sectors of industry and academia,” Lumley said. Recipients of the David E. Lumley Young Scientist Scholarship for Energy and Environmental Science will be expected to present a paper and to participate in various student activities at Fall Meeting. “Meeting some of the ‘giants’ of geoscience and getting their feedback on research is a big deal for these young students. We sometimes lose sight of this,” he said.

  1. Characteristics of a sandy depositional lobe on the outer Mississippi fan from SeaMARC IA sidescan sonar images

    USGS Publications Warehouse

    Twichell, David C.; Schwab, William C.; Nelson, C. Hans; Kenyon, Neil H.; Lee, Homa J.

    1992-01-01

    SeaMARC IA sidescan sonar images of the distal reaches of a depositional lobe on the Mississippi Fan show that channelized rather than unconfined transport was the dominant transport mechanism for coarse-grained sediment during the formation of this part of the deep-sea fan. Overbank sheet flow of sands was not an important process in the transport and deposition of the sandy and silty sediment found on this fan. The dendritic distributary pattern and the high order of splaying of the channels, only one of which appears to have been active at a time, suggest that coarse-grained deposits on this fan are laterally discontinuous.

  2. [Pharmacists as pioneers in porcelain production: what the service, Flora Danica owe to the Bordeaux's apothecary Marc-Hilaire Vilaris].

    PubMed

    Devaux, Guy

    2004-01-01

    In 1766, The Bordeaux's apothecary Marc-Hilaire Vilaris (1719-1792) identified with certainty a kaolin's deposit at Saint-Yrieix, in the country of Limousin, allowing so the porcelain manufacture in France and the development of a china clay's and porcelain's dough trade. Archives documents give evidence of regularly supplies of limousin's raw materials by the pharmacist Frantz Heinrich Müller (1732-1820), Director of the Royal china's Manufactury of Denmark, some time before production of the famous table service Flora Danica.

  3. Sea-floor observations in the tongue of the ocean, Bahamas: An Argo/SeaMARC survey

    USGS Publications Warehouse

    Schwab, W.C.; Uchupi, E.; Ballard, Richard D.; Dettweiler, T.K.

    1989-01-01

    SeaMARC side-scan sonographs and Argo video and photographic data suggest that the recent sedimentary environment of the floor of the Tongue of the Ocean is controlled by an interplay of turbidity current flow from the south, sediment spill-over from the carbonate platform to the east (windward side), and rock falls from the west carbonate escarpment (lee side). The spill-over forms a sandy sedimentary deposit that acts as a topographic obstruction to the turbidity current flow from the south. This obstruction is expressed by the westward migration of a northwest-southeast oriented turbidity-current-cut channel. ?? 1989 Springer-Verlag New York Inc.

  4. [Pharmacists as pioneers in porcelain production: what the service, Flora Danica owe to the Bordeaux's apothecary Marc-Hilaire Vilaris].

    PubMed

    Devaux, Guy

    2004-01-01

    In 1766, The Bordeaux's apothecary Marc-Hilaire Vilaris (1719-1792) identified with certainty a kaolin's deposit at Saint-Yrieix, in the country of Limousin, allowing so the porcelain manufacture in France and the development of a china clay's and porcelain's dough trade. Archives documents give evidence of regularly supplies of limousin's raw materials by the pharmacist Frantz Heinrich Müller (1732-1820), Director of the Royal china's Manufactury of Denmark, some time before production of the famous table service Flora Danica. PMID:15264339

  5. Characteristics of a sandy depositional lobe on the outer Mississippi fan from SeaMARC IA sidescan sonar images

    SciTech Connect

    Twichell, D.C.; Schwab, W.C. ); Nelson, C.H.; Lee, H.J. ); Kenyon, N.H. )

    1992-08-01

    SeaMARC IA sidescan sonar images of the distal reaches of a depositional lobe on the Mississippi Fan show that channelized rather than unconfined transport was the dominant transport mechanism for coarse-grained sediment during the formation of this part of the deep-sea fan. Overbank sheet flow of sands was not an important process in the transport and deposition of the sandy and silty sediment found on this fan. The dendritic distributary pattern and the high order of splaying of the channels, only one which appears to have been active at a time, suggest that coarse-grained deposits on this fan are laterally discontinuous.

  6. 2',5'-Oligoadenylate synthetase 1(OAS1) inhibits PRRSV replication in Marc-145 cells.

    PubMed

    Zhao, Jinhua; Feng, Na; Li, Zhenhong; Wang, Peng; Qi, Ziyu; Liang, Wan; Zhou, Xiang; Xu, Xuewen; Liu, Bang

    2016-08-01

    Porcine reproductive and respiratory syndrome virus (PRRSV) is an economically destructive disease for global pig industry. Although its invasion mechanism is clear, the knowledge of pathogen and host interaction is less known. Here, we found that PPRSV infection led to induction of 2', 5'-oligoadenylate synthetase gene 1(OAS1), an important interferon-stimulated gene. More importantly, ectopic overexpression of OAS1 significantly restricted the replication of PRRSV in 24 and 36 h post-infection in Marc-145 cells, and indirect immunofluorescence assay with antibody against PRRSV N protein displayed significantly lower frequency of fluorescence stained cells and reduced cytopathogenic effects of PRRSV on OAS1-transfected Marc-145 cells. Meanwhile, knockdown of endogenous OAS1 increased the PRRSV ORF7 mRNA level to 1.6 and 1.7 times of that in control in 24 and 36 h post-infection of PRRSV, and led to approximate 5.5 times increase of the frequency of fluorescence positive cells compared to negative control (p < 0.01). The obtained results strongly support a direct restriction function of OAS1 to PRRSV replication, which may contribute to the antiviral effect of the interferon system on PRRSV replication. PMID:27395032

  7. STS-86 Mission Specialist David Wolf suits up

    NASA Technical Reports Server (NTRS)

    1997-01-01

    STS-86 Mission Specialist David A. Wolf gets assistance from a suit technician while donning his orange launch and entry suit in the Operations and Checkout Building. This will be Wolfs second flight. He and the six other crew members will depart shortly for Launch Pad 39A, where the Space Shuttle Atlantis awaits liftoff on a 10-day mission slated to be the seventh docking of the Space Shuttle with the Russian Space Station Mir. Wolf will transfer to the Mir 24 crew, replacing U.S. astronaut C. Michael Foale, who will return to Earth aboard Atlantis with the rest of the STS-86 crew. Wolf is expected to live and work aboard the Russian space station for about four months.

  8. David Ayman, MD: an early investigator of clinical hypertension.

    PubMed

    Materson, Barry J; Leclercq, Baudouin

    2005-04-01

    Dr. David Ayman (1901-1986) was an astute clinician and observer who challenged medical dogma by performing placebo-controlled studies and by meticulous measurement of blood pressure under standardized conditions. He demonstrated that almost all drugs reported to have an antihypertensive effect in the early 20th century had achieved nothing more than placebo response. He noted the marked variability of blood pressure and devised methods to reduce that variability. These observations led to his publications concerning what is now known as "white coat" or office hypertension. He determined blood pressure personally in 1524 members of 277 families over three generations and made observations on the hereditary nature of hypertension that countered the single-gene thinking of the day. His work is proof that clinical inquisitiveness, hard work, and the courage to challenge conventional wisdom can result in significant contributions to medicine and science. PMID:15860961

  9. Astronaut David Brown talks with team members from South Carolina

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Astronaut David Brown looks over the robot named 'L'il Max' with members of the team The Bot Kickers! from Northwestern High School, Rock Hill, S.C. Students from all over the country are at the KSC Visitor Complex for the FIRST (For Inspiration and Recognition of Science and Technology) Southeast Regional competition being held March 9-11 in the Rocket Garden. Teams of high school students are testing the limits of their imagination using robots they have designed, with the support of business and engineering professionals and corporate sponsors, to compete in a technological battle against other schools' robots. Of the 30 high school teams competing, 16 are Florida teams co- sponsored by NASA and KSC contractors. Local high schools participating are Astronaut, Bayside, Cocoa Beach, Eau Gallie, Melbourne, Melbourne Central Catholic, Palm Bay, Rockledge, Satellite, and Titusville.

  10. Astronaut David Brown talks to FIRST team members

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Astronaut David Brown talks with FIRST team members, Baxter Bomb Squad, from Mountain Home High School, Mountain Home, Ariz., during the FIRST competition. Students from all over the country are at the KSC Visitor Complex for the FIRST (For Inspiration and Recognition of Science and Technology) Southeast Regional competition March 9-11 in the Rocket Garden. Teams of high school students are testing the limits of their imagination using robots they have designed, with the support of business and engineering professionals and corporate sponsors, to compete in a technological battle against other schools' robots. Of the 30 high school teams competing, 16 are Florida teams co-sponsored by NASA and KSC contractors. Local high schools participating are Astronaut, Bayside, Cocoa Beach, Eau Gallie, Melbourne, Melbourne Central Catholic, Palm Bay, Rockledge, Satellite, and Titusville.

  11. Astronaut David Brown poses with ComBBat team

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Astronaut David Brown poses with members of the team known as ComBBat, representing Central Florida's Astronaut and Titusville high schools. ComBBat was teamed with Boeing at KSC and Brevard Community College. Students from all over the country are at the KSC Visitor Complex for the FIRST (For Inspiration and Recognition of Science and Technology) Southeast Regional competition being held March 9-11 in the Rocket Garden. Teams of high school students are testing the limits of their imagination using robots they have designed, with the support of business and engineering professionals and corporate sponsors, to compete in a technological battle against other schools' robots. Of the 30 high school teams competing, 16 are Florida teams co-sponsored by NASA and KSC contractors. Local high schools participating are Astronaut, Bayside, Cocoa Beach, Eau Gallie, Melbourne, Melbourne Central Catholic, Palm Bay, Rockledge, Satellite, and Titusville.

  12. The Greening of the David L. Lawrence Pittsburgh Convention Center

    NASA Astrophysics Data System (ADS)

    Leahy, Mark

    2009-03-01

    The David L. Lawrence Convention Center is the largest Gold LEED NC (new construction) certified convention center in the USA and the first of its kind in the world. The designation has been awarded by the United States Green Building Council through its Leadership in Energy and Environmental Design (LEED) Green Building Rating System. In this talk we discuss the unique green properties of this 1.5 million square foot Convention Center including the design and use of daylight, natural ventilation and other sustainable design and practices. No other building the size of the Convention Center (1.5 million square feet), uses natural ventilation or can illuminate an exhibition hall entirely through its windows and skylights. Approximately 75% of the convention center's exhibition space is lit by natural daylight. The use of natural ventilation and extensive day lighting is designed to reduce energy consumption by nearly 35% compared to traditional ventilated and lit buildings of a similar size.

  13. David Duke, running for governor, proposes tattooing people with HIV.

    PubMed

    1995-05-19

    Former Ku Klux Klan leader, David Duke, planning a second run for governor of Louisiana, said he would curb the AIDS epidemic by tattooing people who are infected with HIV. His suggestion is to put indelible, glow-in-the-dark tattoos on the genitals of people infected with HIV. According to Duke, it may sound very draconian but it would not demean people. He also believes that tattooing would be legal because courts have a history of supporting the quarantining and institutionalizing of people with infectious diseases, such as tuberculosis. Duke said Cuba has had some success in using quarantines to reduce HIV infection, but he does not think it would work in the United States because it would cost too much. According to Duke, many people who get HIV from irresponsible behavior do not tell their partners that they have AIDS--these people are mad at the world and engage in dangerous behaviors even more. PMID:11362503

  14. Mapping and converting essential Federal Geographic Data Committee (FGDC) metadata into MARC21 and Dublin Core: towards an alternative to the FGDC Clearinghouse

    USGS Publications Warehouse

    Chandler, A.; Foley, D.; Hafez, A.M.

    2000-01-01

    The purpose of this article is to raise and address a number of issues related to the conversion of Federal Geographic Data Committee metadata into MARC21 and Dublin Core. We present an analysis of 466 FGDC metadata records housed in the National Biological Information Infrastructure (NBII) node of the FGDC Clearinghouse, with special emphasis on the length of fields and the total length of records in this set. One of our contributions is a 34 element crosswalk, a proposal that takes into consideration the constraints of the MARC21 standard as implemented in OCLC's World Cat and the realities of user behavior.

  15. Identification of a new cell line permissive to porcine reproductive and respiratory syndrome virus infection and replication which is phenotypically distinct from MARC-145 cell line

    PubMed Central

    2012-01-01

    Background Airborne transmitted pathogens, such as porcine reproductive and respiratory syndrome virus (PRRSV), need to interact with host cells of the respiratory tract in order to be able to enter and disseminate in the host organism. Pulmonary alveolar macrophages (PAM) and MA104 derived monkey kidney MARC-145 cells are known to be permissive to PRRSV infection and replication and are the most studied cells in the literature. More recently, new cell lines developed to study PRRSV have been genetically modified to make them permissive to the virus. The SJPL cell line origin was initially reported to be epithelial cells of the respiratory tract of swine. Thus, the goal of this study was to determine if SJPL cells could support PRRSV infection and replication in vitro. Results The SJPL cell growth was significantly slower than MARC-145 cell growth. The SJPL cells were found to express the CD151 protein but not the CD163 and neither the sialoadhesin PRRSV receptors. During the course of the present study, the SJPL cells have been reported to be of monkey origin. Nevertheless, SJPL cells were found to be permissive to PRRSV infection and replication even if the development of the cytopathic effect was delayed compared to PRRSV-infected MARC-145 cells. Following PRRSV replication, the amount of infectious viral particles produced in SJPL and MARC-145 infected cells was similar. The SJPL cells allowed the replication of several PRRSV North American strains and were almost efficient as MARC-145 cells for virus isolation. Interestingly, PRRSV is 8 to 16 times more sensitive to IFNα antiviral effect in SJPL cell in comparison to that in MARC-145 cells. PRRSV induced an increase in IFNβ mRNA and no up regulation of IFNα mRNA in both infected cell types. In addition, PRRSV induced an up regulation of IFNγ and TNF-α mRNAs only in infected MARC-145 cells. Conclusions In conclusion, the SJPL cells are permissive to PRRSV. In addition, they are phenotypically different

  16. A Cabinet of Mathematical Curiosities at Teachers College: David Eugene Smith's Collection

    ERIC Educational Resources Information Center

    Murray, Diane R.

    2012-01-01

    This dissertation is a history of David Eugene Smith's collection of historical books, manuscripts, portraits, and instruments related to mathematics. The study analyzes surviving documents, images, objects, college announcements and catalogs, and secondary sources related to Smith's collection. David Eugene Smith (1860-1944) travelled…

  17. Building Consensus toward a Shared Purpose: A Profile of President David Gray

    ERIC Educational Resources Information Center

    Dessoff, Alan

    2011-01-01

    The author presents a profile of APPA president David Gray. One might say that David Gray's path into higher education facilities management was anything but traditional. Today, Gray is the assistant vice president of facilities services at Middle Tennessee State University. His professional career, however, actually began in banking. In 1993 he…

  18. 77 FR 67725 - Culturally Significant Object Imported for Exhibition Determinations: “Michelangelo's David Apollo”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-13

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Michelangelo's David Apollo'' SUMMARY... object to be included in the exhibition ``Michelangelo's David Apollo,'' imported from abroad for... display of the exhibit object at the National Gallery of Art, Washington, DC, from on or about December...

  19. Discussion of David Thissen's Bad Questions: An Essay Involving Item Response Theory

    ERIC Educational Resources Information Center

    Wainer, Howard

    2016-01-01

    The usual role of a discussant is to clarify and correct the paper being discussed, but in this case, the author, Howard Wainer, generally agrees with everything David Thissen says in his essay, "Bad Questions: An Essay Involving Item Response Theory." This essay expands on David Thissen's statement that there are typically two principal…

  20. A grid of MARCS model atmospheres for late-type stars. I. Methods and general properties

    NASA Astrophysics Data System (ADS)

    Gustafsson, B.; Edvardsson, B.; Eriksson, K.; Jørgensen, U. G.; Nordlund, Å.; Plez, B.

    2008-08-01

    Context: In analyses of stellar spectra and colours, and for the analysis of integrated light from galaxies, a homogeneous grid of model atmospheres of late-type stars and corresponding flux spectra is needed. Aims: We construct an extensive grid of spherically-symmetric models (supplemented with plane-parallel ones for the highest surface gravities), built on up-to-date atomic and molecular data, and make it available for public use. Methods: The most recent version of the MARCS program is used. Results: We present a grid of about 104 model atmospheres for stars with 2500 K ≤ T_eff ≤ 8000 K, -1 ≤ log g = log (GM/R^2) ≤ 5 (cgs) with various masses and radii, -5 ≤ [Me/H] ≤ +1, with [ α/Fe] = 0.0 and 0.4 and different choices of C and N abundances. This includes “CN-cycled” models with C/N = 4.07 (solar), 1.5 and 0.5, C/O ranging from 0.09 to (normally) 5.0 to also represent stars of spectral types R, S and N, and with 1.0 ≤ ξt ≤ 5 km s-1. We also list thermodynamic quantities (T, P_g, P_e, ρ, partial pressures of molecules, etc.) and provide them on the World Wide Web, as well as calculated fluxes in approximately 108 000 wavelength points. Underlying assumptions in addition to 1D stratification (spherical or plane-parallel) include hydrostatic equilibrium, mixing-length convection and local thermodynamic equilibrium. We discuss a number of general properties of the models, in particular in relation to the effects of changing abundances, of blanketing, and of sphericity. We illustrate positive and negative feedbacks between sphericity and molecular blanketing. We compare the models with those of other available grids and find excellent agreement with plane-parallel models of Castelli & Kurucz (if convection is treated consistently) within the overlapping parameter range. Although there are considerable departures from the spherically-symmetric NextGen models, the agreement with more recent PHOENIX models is gratifying. Conclusions: The models

  1. 77 FR 19610 - Marc Knapp, Inmate #-06450-015, FCI Safford, P.O. Box 9000, Safford, AZ 85548; Order Denying...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Bureau of Industry and Security Marc Knapp, Inmate --06450-015, FCI Safford, P.O. Box 9000, Safford, AZ....O. Box 9000, Safford, AZ 85548, and when acting for or on behalf of Knapp, his...

  2. Exploring the use of Saccharomyces cerevisiae commercial strain and Saccharomycodes ludwigii natural isolate for grape marc fermentation to improve sensory properties of spirits.

    PubMed

    Bovo, Barbara; Carlot, Milena; Lombardi, Angiolella; Lomolino, Giovanna; Lante, Anna; Giacomini, Alessio; Corich, Viviana

    2014-08-01

    In Mediterranean countries the most diffuse practice to obtain the valorization of grape marc, the main by-product from winemaking, is the production of spirits. During this process, marc storage for sugar fermentation represents a crucial step, since side-fermentations leading to off-flavours production can very easily occur. In this study we evaluated the effect of the addition of two yeast strains, inoculated separately at the beginning of the storage period, into marcs from two Italian grape varieties with the aim to control the development of autochthonous microbiota and to improve spirit quality. The presence of the inoculated strains was monitored by means of PCR-based approaches. A commercial Saccharomyces cerevisiae strain, chosen as this species is notably the best ethanol producer, showed excellent ability to dominate the autochthonous microflora and to reduce off-flavours as demonstrated by chemical analysis and sensory evaluation. A Saccharomycodes ludwigii strain, chosen for increasing varietal compounds thus enhancing spirit aroma, showed a level of implantation not sufficient to assure a clear beneficial effect on quality. The implantation level of this strain was affected by S. cerevisiae competition since the highest level was found in grape marc with lower sugar content, where indigenous S. cerevisiae were less persistent. PMID:24750811

  3. David de Wied: Eminent scientist and academic leader: A personal note.

    PubMed

    Gispen, Willem Hendrik

    2010-01-10

    David de Wied was a natural leader with many a talent. He was the director of the Rudolf Magnus Institute at Utrecht University and president of the Royal Netherlands Academy of Arts and Sciences. He coached over 75 Ph.D. students and hosted some 200 foreign scientists who joined him in his multidisciplinary neuropeptide research. Many of them became lifelong friends, frequenting the home of Liedje and David de Wied. Born in Deventer (The Netherlands) on January 12th, 1925, David de Wied's early boyhood first in Deventer and later in Leeuwarden appears to have been no different from that of any other provincial Dutch boys in pre-war Holland. After the war David enrolled at Groningen University to study medicine. Subsequently he specialized in experimental pharmacology. To understand the determination of David de Wied is to understand the drive of a Jewish young man, who during the war, had been forced to go underground and unable to develop in a free and independent manner. Therefore, later in life, time became very precious to him and everything that came across his path had to be taken seriously. In this short sketch of David de Wied I will try to highlight his outstanding scientific accomplishments as well as his personality as both have inspired a generation of young scientists. It is a great honour and a pleasure to be part of this meeting in memory of David de Wied.

  4. Characterization Report for the David Witherspoon Screen Art Site

    SciTech Connect

    Phyllis C. Weaver

    2011-01-31

    The U.S. Department of Energy (DOE) Oak Ridge Office (ORO) of Environmental Management (EM) requested the technical assistance of Oak Ridge Institute for Science and Education (ORISE) to characterize a tract of land associated with the David Witherspoon, Incorporated (DWI) Volunteer Equipment and Supply Company (VESC). This tract of land (hereinafter referred to as Screen Arts) is located in the Vestal Community in the 2000-block of Maryville Pike in south Knoxville, Tennessee, as shown in Figure A-1. This tract of land has been used primarily to store salvaged equipment and materials for resale, recycle, or for disposal in the former landfill once operated by DWI. The DWI Site industrial landfill and metal recycling business had been permitted by the Tennessee Division of Radiological Health to accept low-level radiologically contaminated metals. DWI received materials and equipment associated with operations from DOE sites, including those in Oak Ridge, Tennessee; Paducah, Kentucky; and Portsmouth, Ohio. It is likely that items stored at Screen Arts may have contained some residual radiological materials.

  5. Sir David Wilkie (1882-1938): surgeon, scientist and philanthropist.

    PubMed

    Macintyre, Iain

    2007-11-01

    Until the start of the 20th century, appointment to a chair in surgery in Britain was usually awarded in recognition of an already successful career. Sir David Wilkie was among the first of the new breed of professors of surgery appointed at a relatively young age to develop surgical research and undergraduate teaching. At the University of Edinburgh, he established a surgical research laboratory from which was to emerge a cohort of young surgical researchers destined to become the largest dynasty of surgical professors yet seen in the British Isles. He is widely regarded as the father of British academic surgery. Born in the same Scottish village as the writer JM Barrie (1860-1937), like Barrie, Wilkie became a philanthropist. Both men were to achieve eminence in later life and when Barrie was appointed Chancellor of Edinburgh University, their friendship developed. Barrie's legacy to Great Ormond Street Children's Hospital was one of the greatest ever acts of medical philanthropy, and Wilkie too proved to be a generous benefactor of the disadvantaged.

  6. David Florida Laboratory: Support for mobile satellite communications

    NASA Technical Reports Server (NTRS)

    Dumoulin, Jean-Guy; Mamen, Rolf

    1995-01-01

    The comprehensive integration and environmental (including RF) test facilities of the Canadian Space Agency's David Florida Laboratory (CSA)(DFL) were used extensively for the MSAT Program. Following a description of the facilities, the paper outlines their application to the qualification of the two MSAT satellites following an overview of the test plan. Particular emphasis is given to passive intermodulation measurement (PIM) demands, which for the MSAT satellites, contributed to the need to extend the anechoic chamber. The extended chamber was also used for an EMC test and SAR signature test of the RADARSAT satellite. The DFL's facilities are being used for additional aspects of mobile satellite communications. One shielded anechoic Extra High Frequency (EHF) chamber and associated test equipment are employed predominantly for measuring the performance of the IRIDIUM satellites' Engineering Model Gateway Moveable Antennas (EM)(GMA). Other chambers are used for testing aeronautical antennas on behalf of Inmarsat. Still others combine thermal and PIM testing. The paper concludes with a review of the test requirements of evolving satcom missions such as Inmarsat Aero-1.

  7. Glycoprotein 5 of porcine reproductive and respiratory syndrome virus strain SD16 inhibits viral replication and causes G2/M cell cycle arrest, but does not induce cellular apoptosis in Marc-145 cells

    SciTech Connect

    Mu, Yang; Li, Liangliang; Zhang, Beibei; Huang, Baicheng; Gao, Jiming; and others

    2015-10-15

    Cell apoptosis is common after infection with porcine reproductive and respiratory syndrome virus (PRRSV). PRRSV GP5 has been reported to induce cell apoptosis. To further understand the role of GP5 in PRRSV induced cell apoptosis, we established Marc-145 cell lines stably expressing full-length GP5, GP5{sup Δ84-96} (aa 84-96 deletion), and GP5{sup Δ97-119} (aa 97-119 deletion). Cell proliferation, cell cycle progression, cell apoptosis and virus replication in these cell lines were evaluated. Neither truncated nor full-length GP5 induced cell apoptosis in Marc-145 cells. However, GP5{sup Δ97-119}, but not full-length or GP5{sup Δ84-96}, induced a cell cycle arrest at the G2/M phase resulting in a reduction in the growth of Marc-145 cells. Additionally, GP5{sup Δ84-96} inhibited the replication of PRRSV in Marc-145 cells through induction of IFN-β. These findings suggest that PRRSV GP5 is not responsible for inducing cell apoptosis in Marc-145 cells under these experimental conditions; however it has other important roles in virus/host cell biology. - Highlights: • Marc-145 cell lines stable expression PRRSV GP5 or truncated GP5 were constructed. • GP5{sup Δ97-119} expression in Marc-145 cell induced cell cycle arrest at G2/M phase. • Expression of GP5 and truncated GP5 could not induce Marc-145 cells apoptosis. • PRRSV replication in Marc-145-GP5{sup Δ84-96} was significantly inhibited.

  8. Astronaut David Wolf draws blood from Martin Fettman for SLS-2 investigations

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Inside the science module aboard the Earth-orbiting Space Shuttle Columbia, Astronaut David A. Wolf draws blood from payload specialists Martin J. Fettman, DVM. Blood samples from crew members are critical to several Spacelab Life Sciences (SLS-2) investigations.

  9. An Inside View: Investigative Reporter David Weir on Searching for the Truth.

    ERIC Educational Resources Information Center

    Brown, Donal

    1986-01-01

    Discusses the work of David Weir, who believes that reporters need to cultivate open-mindedness, detachment from their own work, and ability to see beyond their own prejudices and predispositions to alter hypotheses to fit the facts. (SRT)

  10. Grape Marc Extract-Induced Defense Reactions and Protection against Phytophthora parasitica Are Impaired in NahG Tobacco Plants.

    PubMed

    Benouaret, Razik; Goupil, Pascale

    2015-08-01

    Grape marc extract (GME) acts as an elicitor of plant defense responses. This study analyzed GME-induced plant defense reactions in NahG transgenic tobacco. Leaf infiltration of NahG leaves revealed HR-like reactions with reduced lesions and weak deployment of autofluorescent compounds in the surrounding infiltrated tissues. The β-1,3-glucanase PR2-, endochitinase PR3-, and osmotin PR5-target transcript levels were strongly lowered in NahG leaves, and the mutant failed to accumulate the antimicrobial PR1 transcripts. GME-induced protection against Phytophthora parasitica var. nicotianae (Ppn) was evaluated on tobacco leaves. The antimicrobial properties of GME against Ppn were evidenced using a range of in vitro tests. GME-sprayed wild-type leaves showed reduced infection areas, whereas GME failed to induce a protective effect against Ppn in NahG leaves. The results suggest that GME-induced plant defense reactions in tobacco plants was mediated by salicylic acid (SA) and that GME-induced protection against Ppn could be the combined result of antimicrobial and defense actions.

  11. Remedial investigation/feasibility study for the David Witherspoon, Inc., 901 Site, Knoxville, Tennessee: Volume 2, Appendixes

    SciTech Connect

    1996-10-01

    This document contains the appendixes for the remedial investigation and feasibility study for the David Witherspoon, Inc., 901 site in Knoxville, Tennessee. The following topics are covered in the appendixes: (A) David Witherspoon, Inc., 901 Site Historical Data, (B) Fieldwork Plans for the David Witherspoon, Inc., 901 Site, (C) Risk Assessment, (D) Remediation Technology Discussion, (E) Engineering Support Documentation, (F) Applicable or Relevant and Appropriate Requirements, and (G) Cost Estimate Documentation.

  12. The paradox of drowned reefs: A Caribbean example mapped using SeaMARC II side-scan sonar

    SciTech Connect

    Grote, D.; Mann, P. )

    1990-05-01

    Three models for the drowning of carbonate platforms and associated fringing coral reefs include (1) rapid submergence below the euphotic zone by tectonic subsidence and sea level rise; (2) excess nutrients in the water; and (3) burial by prograding marine siliclastic sediments. To examine these mechanisms on a regional scale, the authors mapped drowned barrier reef tracts around the active carbonate banks of the Nicaraguan Rise using SeaMARC II sidescan sonar, 3.5 KHz, and digital single channel reflection techniques. The reef tracts exhibited high sonar backscatter and were prominently displayed on sidescan images. Characteristic features of the reef tracts include (1) uneroded and slightly sinuous mounds that crop out on the sea floor and closely following bathymetric contours; (2) reef mounds that typically occur in stairstep sets of two to three terraces; (3) water depths at the crest of the reef mounds that range from 1,050 to 1,500 m; and (4) reef mounds that extend for 1,200 km around the base of the slope (depth 1,300 m) of an active carbonate platform in a moderately active, intraplate setting (Pedro Bank) and along the crest of a submerged fault block in a highly active, interplate setting (Bay Islands Ridge, ridge crest depth at 1,600 m). Because these newly discovered reef tracts have not been dredged, their ages and compositions remain unknown. Based on the observed sea floor outcrop, regional extent, and approximate correlation in water depth of the reef tracts, mechanisms 1 and 2 appear to be the most likely drowning mechanisms.

  13. Volcanic Episodicity and a Non-Steady State Rift Valley Along Northeast Pacific Spreading Centers: Evidence From Sea MARC I

    NASA Astrophysics Data System (ADS)

    Kappel, Ellen S.; Ryan, William B. F.

    1986-12-01

    Sea MARC I side-looking sonar images and Sea Beam bathymetry along a 400-km stretch of the Juan de Fuca Ridge crest provide evidence that excessive extrusive volcanism periodically builds a crestal ridge along the axis of seafloor spreading. An elongate summit depression (ESD), or rift valley, is commonly observed in the spine of this crestal ridge. The crestal ridge volcanic landform has a distinctive shape that is recognized in bathymetric contours both along the spreading axis and at least up to 30 km away from the axis. The landform has a plan-form shape that resembles a side view of an archer's bow with the long dimension of the bow form parallel to the strike of the ridge. In cross section, the bow form is flat on top and has steep flanks. These bow-form shapes can be explained by magma that rises into the crust at a discrete center and flows laterally into belts of ridge-parallel dikes, similar to Icelandic fissure eruptions. Both the variable dimensions of the ESD along axis of the Juan de Fuca Ridge and the relationship among volcanic flow morphologies within and beyond the ESD suggest the four different segments of the Juan de Fuca Ridge presented in detail here display different stages in a cycle of oceanic crust accretion. This cycle includes episodes in which there is (1) extrusive volcanic construction which widen the crestal ridge prior to the collapse of the summit depression, (2) collapse within the summit region of the crestal ridge to form an ESD during a phase of volcanic inactivity, and (3) renewed magmatism in the ESD as its floor widens by extension and brittle fracture of the upper crust. This episodic model implies that the width of the young seafloor affected by volcanic extrusion or dominated by tectonic stretching varies through time.

  14. Interview with David H. Jonassen: Looking at the Field of Educational Technology from Radical and Multiple Perspectives

    ERIC Educational Resources Information Center

    Simsek, Ali

    2012-01-01

    There are people whose names are identified with their fields. When an outsider wants to learn about the field of educational technology and enters some keywords, David H. Jonassen is perhaps one the few people whose names will appear instantly. Of course, this is not without reasons. David H. Jonassen has produced enormous amount of work…

  15. Commentary on "An Evolutionarily Informed Education Science" by David C. Geary

    ERIC Educational Resources Information Center

    Ellis, George F. R.

    2008-01-01

    Dr. David C. Geary's article centers on the concept of inherited folk psychology modules, together with the idea of a transition from primary to secondary learning. This article suggests that there exist only effective folk psychology modules, which are the result of interaction of inherited primary emotional systems with the physical, biological,…

  16. Astronaut David Wolf participates in training for contingency EVA in WETF

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Astronaut David A. Wolf participates in training for contingency extravehicular activity (EVA) for the STS-58 mission. The mission specialist was about to be submerged to a point of neutral buoyancy in the JSC Weightless Environment Training Facility (WETF). In this view, Wolf is aided by technicians in donning the gloves for his extravehicular mobility unit (EMU).

  17. Q & A with Ed Tech Leaders: Interview with David M. Monetti

    ERIC Educational Resources Information Center

    Fulgham, Susan M.; Shaughnessy, Michael F.

    2014-01-01

    Contributing editors Susan Fulgham and Michael Shaughnessy present their interview with David M. Monetti, Professor in the Department of Psychology and Counseling at Valdosta State University. Monetti teaches courses in educational psychology, learning, and measurement and evaluation. He is actively involved with the public schools as a researcher…

  18. Forging Futures with Teens and Science Fiction: A Conversation with Greg Bear and David Brin.

    ERIC Educational Resources Information Center

    Moltz, Sandy

    2003-01-01

    Presents an interview with Greg Bear and David Brin, two science fiction writers who started Reading for the Future, an international project geared toward secondary school students that shows teachers and librarians how science fiction inspires young readers. Discusses programs that have come out of this group; standards for books geared toward…

  19. Being "Stresslessly Invisible": The Rise and Fall of Videophony in David Foster Wallace's "Infinite Jest"

    ERIC Educational Resources Information Center

    Ribbat, Christoph

    2010-01-01

    In a satiric chapter of David Foster Wallace's novel "Infinite Jest," a mock media expert reports how American consumers of the near future recoil from a new communication device known as "videophony" and return to the voice-only telephone of the Bell Era. This article explores the said chapter in the framework of media theories reading the…

  20. The Camp David Ceremony and the Genre of the Presidential Parasocial Broadcast Announcement.

    ERIC Educational Resources Information Center

    Houser, William Evan

    In 1978, the historic Camp David Peace Accords between Egypt and Israel were signed in a ceremony broadcast from the White House. The ceremony may be seen as a member of a rhetorical genre informally called the Presidential Parasocial Broadcast Announcement, but with a new twist. The genre has its roots in the Fireside Chats of Franklin D.…

  1. Constructing the Path to Tomorrow: Strategic Planning and Implementation in the David Douglas School District.

    ERIC Educational Resources Information Center

    Cole, Richard

    Following a brief introduction to the David Douglas School District community and schools located in a partly unincorporated area of Portland/Multnomah County, Oregon, this publication describes the district's prior annual goal-setting process and its evolving Vision 90's strategic-planning and implementation process (SPI). Strategic-planning…

  2. Finding Our Way Back to Healthy Eating: A Conversation with David A. Kessler

    ERIC Educational Resources Information Center

    Azzam, Amy M.

    2009-01-01

    In this interview, David Kessler, former commissioner of the Food and Drug Administration, explains why so many people overeat. Changing lifestyles promote the constant availability of food and around-the-clock eating. In today's highly processed foods, food companies are able to dial in the exact amount of fat, sugar, and salt that will make…

  3. The Archives of the History of American Psychology: An Interview with David B. Baker.

    ERIC Educational Resources Information Center

    Prieto, Loreto R.

    2001-01-01

    Presents an interview with David B. Baker, Director of the Archives of the History of American Psychology. Covers topics such as: Baker's interest in the history of psychology, his work at the Archives of the History of American Psychology, and recommendations for teachers when addressing history in non-history courses. (CMK)

  4. Remapping Place and Narrative in Native American Literature: David Treuer's "The Hiawatha"

    ERIC Educational Resources Information Center

    Kirwan, Padraig

    2007-01-01

    David Treuer's 1997 novel, "The Hiawatha," engages the traditional literary strategies employed by Native American writing, compares those strategies to earlier narratives (Native American and canonically American), offers a reassessment of indigenous novelistic structures, engages critical responses to tribal fiction, and does so in response to…

  5. David Hume's Monetary Theory Revisited: Was He Really a Quantity Theorist and an Inflationist?

    ERIC Educational Resources Information Center

    Wennerlind, Carl

    2005-01-01

    David Hume's monetary theory has been controversial since its formulation. Lately, the focus has been on Hume's alleged misapplication of the quantity theory of money. While he appears to subscribe to a simple quantity theory with money neutrality, in a famously contested passage in the essay Of Money, he violates the neutrality condition by…

  6. Paul Voosen Receives 2013 David Perlman Award for Excellence in Science Journalism—News: Citation

    NASA Astrophysics Data System (ADS)

    Zaneski, Cyril T.

    2014-01-01

    It's my pleasure to nominate Paul Voosen, the former science reporter for Greenwire, for the David Perlman award. Last November, as Superstorm Sandy pounded the East Coast of the United States, Paul found himself stranded for several days in Miami, mourning a recently deceased family member.

  7. 76 FR 66995 - David T. Koon, M.D.; Revocation of Registration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ... practitioner whose state license has been suspended or revoked. David W. Wang, 72 FR 54297, 54298 (2007); Sheran Arden Yeates, 71 FR 39130, 39131 (2006); Dominick A. Ricci, 58 FR 51104, 51105 (1993); Bobby Watts, 53 FR 11919, 11920 (1988). See also 21 U.S.C. 824(a)(3) (authorizing the revocation of a...

  8. Children and Religious Education in an Age of Globalization: Learning from David Ng

    ERIC Educational Resources Information Center

    Mercer, Joyce Ann

    2002-01-01

    This article assesses David Ng's contribution to religious education with children. Ng offered practical strategies for full inclusion of children in faith communities. One limitation in Ng's work on children is its lack of attention to the role of culture, an unusual omission given his interest in multicultural religious education. This gap…

  9. David Dorfman's "Here": A Community-Building Approach in Dance Education

    ERIC Educational Resources Information Center

    Parrish, Mila

    2009-01-01

    Over a three-month period, Arcadia High School and Arizona State University formed a community partnership with the help of New York modern dance choreographer David Dorfman to create an original dance titled "Here." Dorfman's community-building approach is based on personal refection, collaboration, critical thinking, problem solving, genuine…

  10. Builders Challenge High Performance Builder Spotlight: David Weekley Homes, Houston, Texas

    SciTech Connect

    2009-12-22

    Building America Builders Challenge fact sheet on David Weekley Homes of Houston, Texas. The builder plans homes as a "system," with features such as wood-framed walls that are air-sealed then insulated with R-13 unfaced fiberglass batts plus an external covering of R-2 polyisocyanurate rigid foam sheathing.

  11. Henry David Thoreau: American Transcendentalism and the Implications for Rhetoric in American Civic Education.

    ERIC Educational Resources Information Center

    Grapsy, Ronald P., Jr.

    The American Philosopher Henry David Thoreau provides modern students an important perspective on the state and operation of democratic institutions and society. Many critics of his philosophy cite the author's inability to live up to his articulated tenets as grounds to dismiss the exhortative writings as idealistic and implausible. This essay…

  12. A Life in Research, an Adventure in Creativity: An Interview with David W. Chan

    ERIC Educational Resources Information Center

    Henshon, Suzanna E.

    2011-01-01

    This article presents an interview with David W. Chan, founding director of the Program for the Gifted and Talented at the Chinese University of Hong Kong. Chan has worked at the university for nearly 30 years, first in the Department of Psychiatry and then in the Department of Educational Psychology. Currently, he is also an adjunct professor of…

  13. David Maurice's contributions to optical ophthalmic instrumentation: roots of the scanning slit clinical confocal microscope.

    PubMed

    Masters, Barry R

    2004-03-01

    This paper explores the seminal contributions of David Maurice to the field of ophthalmic instrumentation. His development of the specular microscope, the scanning slit optical confocal microscope, and the corneal microfluorometer resulted in advances in our understanding of corneal morphology, physiology, and pathology. The development of the scanning slit, clinical confocal microscope is not a new paradigm or a paradigm shift, but a continuous series of interlinked technical advances from the early work of Vogt to Thaer's development of a clinical confocal microscope. For each instrument both the connection to the prior work of others and the unique advances are discussed and contrasted. This paper develops the connections and parallel developments in the instrument developments of Goldmann, Maurice, Svishchev, Baer, Koester, Masters, and Thaer. The evidence in support of the thesis consists of published papers, patents, personal communication, and study of Goldmann's book collection in Bern. A second theme is that knowledge of physics is a prerequisite for optical instrument development in ophthalmology. David Maurice had a university degree in physics and Hans Goldmann learned physics from his books. The contributions of David Maurice to optical instrumentation follow the major contributions of Goldmann and facilitated and stimulated other scientists who acknowledged their important intellectual debt to David Maurice.

  14. Improving the Quality of the Teaching Force: A Conversation with David C. Berliner.

    ERIC Educational Resources Information Center

    Scherer, Marge

    2001-01-01

    In a question-and-answer session, David C. Berliner discusses wide range of topics related to current state of the teaching profession, including qualities of the expert teacher, attracting higher quality teachers, teacher career-stage programs, merit pay, and promising reforms for teacher education in last decade. (PKP)

  15. 76 FR 39865 - Mr. David Creasey; Notice of Availability of Environmental Assessment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ... regulations, 18 CFR Part 380 (Order No. 486, 52 FR 47897), the Office of Energy Projects has reviewed the... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Mr. David Creasey; Notice of Availability of Environmental Assessment...

  16. An Interview with David Rindskopf: A Leading Voice on Teaching Statistics and Methodology

    ERIC Educational Resources Information Center

    Bembenutty, Hefer

    2011-01-01

    This article presents an interview with David Rindskopf, a Distinguished Professor of Educational Psychology and Psychology at the City University of New York Graduate Center, where he has taught since 1979. His research and teaching are in the area of applied statistics, measurement, and research design. He is a fellow of the American Statistical…

  17. David Douglas Duncan's Changing Views on War: An Audio-Visual Presentation.

    ERIC Educational Resources Information Center

    Politowski, Richard

    This paper is the script for a slide presentation about photographer David Douglas Duncan and his view of war. It is intended to be used with slides made from pictures Duncan took during World War II, the Korean War, and the war in Viet Nam and published in various books and periodicals. It discusses a shift in emphasis to be seen both in the…

  18. On a Theme by Rene David: Comparative Law as "Technique Indispensable."

    ERIC Educational Resources Information Center

    McAuley, Michael

    2002-01-01

    Explores a text by Rene David relating to the teaching of comparative law and the comparative teaching of law. Discusses bijural education as a way to comprehensively teach the civil and common law traditions. Addresses construction of a bijural curriculum and skills of comparative law teaching. (EV)

  19. Physics for Teachers: Understanding Physics: David Cassidy, Gerald Holton, & James Rutherford

    NASA Astrophysics Data System (ADS)

    Hubisz, John L.

    2009-11-01

    Physics for Teachers: Understanding Physics, by David Cassidy, Gerald Holton, & James Rutherford and published by Springer Verlag, New York, NY 10010 (2002), pp. xxiii + 851 80.00 hardback. ISBN 0-387-98756-8. Student Guide & Instructor Guide are also available. The text and Instructor Guide are available online at http://www.dcassidybooks.com/up.html

  20. Astronaut David Scott undergoes water egress training in building 260A

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Astronaut David R. Scott, pilot of the Gemini 8 prime crew, undergoes water egress training in a special tank in building 260A at the Manned Spacecraft Center (MSC), Houston, Texas. An MSC swimmer assists in the training exercise. A boilerplate model of a Gemini spacecraft floats in water beside Scott.

  1. David Brearly: Soldier-Statesmen of the Constitution. A Bicentennial Series No. 18.

    ERIC Educational Resources Information Center

    Army Center of Military History, Washington, DC.

    David Brearly was a student of the Enlightenment philosophers and English jurists who taught that a contract existed between the individual and the state, and this exposure influenced him as a framer of the Constitution, with its careful definitions of the obligations of government and the rights of citizens. This booklet on Brearly is one in a…

  2. Education, Educational Research, and the "Grammar" of Understanding: A Response to David Bridges

    ERIC Educational Resources Information Center

    Smeyers, Paul

    2009-01-01

    This article is the author's response to a paper presented by David Bridges. Bridges' central question: "Is there something exclusive and superior about insider understanding which the outsider cannot understand?" is indeed not only crucial to the contexts he explicitly deals with, i.e. religious understanding, ethnographic research and…

  3. David Hurst Thomas and the Historical Archaeology of the Spanish Borderlands.

    ERIC Educational Resources Information Center

    Snead, James E.

    2000-01-01

    Discusses David Hurst Thomas' archaeological work on the Spanish borderlands, which integrates field archaeology and documentary history. Focuses on locating and studying the Santa Catalina de Guale. Addresses his project on the Pueblo San Marcos that will further test his ideas about the Spanish mission period. (CMK)

  4. David F. Treagust: Congenial Soul, Science Educator, and International Research Leader

    ERIC Educational Resources Information Center

    Tobin, Kenneth; Rennie, Leonie; Venville, Grady; Chu, Hye-Eun; Fensham, Peter; Gallagher, James; Duit, Reinders; Graeber, Wolfgang; van den Berg, Ed; Hand, Brian; Ritchie, Stephen; Dillon, Justin

    2011-01-01

    For almost a half century David F. Treagust has been an exemplary science educator who has contributed through his dedication and commitments to students, curriculum development and collaboration with teachers, and cutting edge research in science education that has impacted the field globally, nationally and locally. A hallmark of his outstanding…

  5. 78 FR 60273 - David E. Cereghino, Idaho County Light & Power Cooperative Association, Inc.; Notice of Transfer...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-01

    ... Association, Inc.; Notice of Transfer of Exemption 1. By letter filed March 25, 2011, David E. Cereghino and Idaho County Light & Power Cooperative Association, Inc. informed the Commission that the exemption from... transferred to Idaho County Light & Power Cooperative Association, Inc. The project is located on John...

  6. An Evaluation Of Family Life Education At David Thompson Secondary School.

    ERIC Educational Resources Information Center

    Leslie, Susan

    The Family Life Education program at David Thompson Secondary School is a one semester course dealing with human sexuality. Given to eleventh grade students the course is directed at helping students understand the emotional and social dimensions of their sexuality. Because the emphasis in the course was on feeling, not fact, this evaluation of…

  7. Inconvenient Truths: A Response to the Article by David Stoesz, "The Child Welfare Cartel"

    ERIC Educational Resources Information Center

    Clark, James J.; Yegidis, Bonnie L.

    2016-01-01

    David Stoesz offers a sweeping critique of the Children's Bureau and social work education by claiming the existence of a "child welfare cartel." He also attacks the quality of social work education and research, which he claims has poorly invested government funding and helped create the unmitigated failures of the American child…

  8. World's Youth Connect through Global Nomads Group: An Interview with GNG's David Macquart

    ERIC Educational Resources Information Center

    Morrison, James L.; Macquart, David

    2006-01-01

    Editor-in-chief James L. Morrison talks with David Macquart, co-founder of the Global Nomads Group (GNG), a group dedicated to improving children's cultural understanding by bringing the world into the classroom using videoconferencing technology. GNG moderates video conferences between K-12 classes in different countries, organizes virtual…

  9. Discussion of David Thissen's Bad Questions: An Essay Involving Item Response Theory

    ERIC Educational Resources Information Center

    Ackerman, Terry

    2016-01-01

    In this commentary, University of North Carolina's associate dean of research and assessment at the School of Education Terry Ackerman poses questions and shares his thoughts on David Thissen's essay, "Bad Questions: An Essay Involving Item Response Theory" (this issue). Ackerman begins by considering the two purposes of Item Response…

  10. Bridging the Gap between High School and College: An Interview with David Spence

    ERIC Educational Resources Information Center

    Smith, Virginia B.

    2006-01-01

    The National Center for Public Policy and Higher Education and the Council for Adult and Experiential Learning have awarded David Spence, its 2006 Virginia B. Smith Award for Innovative Leadership in Higher Education. Mr. Spence is formerly executive vice chancellor and chief academic officer of the California State University system and now…

  11. David Kirk on Physical Education and Sport Pedagogy: In Dialogue with Steven Stolz (Part 1)

    ERIC Educational Resources Information Center

    Stolz, Steven A.; Kirk, David

    2015-01-01

    Forming the first of two articles, this dialogue begins from the dilemma posed in the writings of David Kirk that physical education is in crisis because the dominant practice of physical education as "sport-techniques" is resistant to change. In order to make sense of crisis discourse, the discussion explores the potential for change in…

  12. A Response to David Kirk: Personal/Professional Views from US Authors

    ERIC Educational Resources Information Center

    Hastie, Peter; van der Mars, Hans

    2014-01-01

    This paper represents the views of two scholars in the USA with respect to the scholar lecture presented by David Kirk at the 2012 BERA -- Physical Education and Sport Pedagogy (PESP) Special Interest Group meeting. We discuss how two unique features of the American universities have an impact on both the corporate nature of our work and our…

  13. Henry David Thoreau, Martin Luther King Jr., and the American Tradition of Protest.

    ERIC Educational Resources Information Center

    Powell, Brent

    1995-01-01

    Maintains that Henry David Thoreau and Martin Luther King, Jr. fundamentally altered the tradition of protest and reform. Compares and contrasts the role of each man in U.S. social and constitutional history. Concludes that while Thoreau lacked the broad influence of King, his writings influenced both King and Mohandas Gandhi. (CFR)

  14. The Fifties ... Fifty Years Later: "Connection" Interviews Historian David Halberstam on a Half Century of Change

    ERIC Educational Resources Information Center

    Connection: The Journal of the New England Board of Higher Education, 2005

    2005-01-01

    This article presents an interview with historian David Halberstam who graduated from Harvard University in 1955 after serving as managing editor of the "Harvard Crimson." Upon graduation, he joined the staff of the "Daily Times Leader" newspaper of West Point, Mississippi, and then moved on to the "Nashville Tennessean," where he covered the…

  15. Simulating the Camp David Negotiations: A Problem-Solving Tool in Critical Pedagogy

    ERIC Educational Resources Information Center

    McMahon, Sean F.; Miller, Chris

    2013-01-01

    This article reflects critically on simulations. Building on the authors' experience simulating the Palestinian-Israeli-American Camp David negotiations of 2000, they argue that simulations are useful pedagogical tools that encourage creative--but not critical--thinking and constructivist learning. However, they can also have the deleterious…

  16. Investing in the Child Welfare Workforce: A Response to David Stoesz

    ERIC Educational Resources Information Center

    Briar-Lawson, Katharine; Leake, Robin; Dickinson, Nancy; McCarthy, Mary; Anderson, Gary; Groza, Victor; Gilmore, Grover C.

    2016-01-01

    Responding to David Stoesz's invited article criticizing the Children's Bureau and the National Child Welfare Workforce Institute (NCWWI), the author's inaccurate assertions are challenged, and new information is provided about the significant work underway to support the child welfare workforce. The Children's Bureau has made historic investments…

  17. Sinkhole-type subsidence over abandoned coal mines in St. David, Illinois. Mine subsidence report, St. David, Illinois. A field survey and analysis of mine subsidence of abandoned coal mines in St. David, Illinois

    SciTech Connect

    Wildanger, E.G.; Mahar, J.; Nieto, A.

    1980-01-01

    This study examined the geologic data, mining history, and subsidence trends of the St. David region. Mine subsidence has occurred due to collapse of the abandoned mine workings. The known subsidence areas have been mapped and described. Results of the study include: (1) St. David has been undermined by both large shipping mines and smaller local mines; (2) sinkholes will continue to develop in this area in response to rock failure and roof collapse above the abandoned mine workings; (3) some primary factors that contribute to the sinkhole problems are the undermining and roof rock composition; (4) sinkholes will be smaller in the future; (5) ten of the 63 sinkholes occurred close enough to structures to cause damage, and only six sinkholes caused damage; (6) ways to minimize potential damage to future homes from sinkhole subsidence are manageable; (7) threats to residents lie in the collapse of heavy walls, brick chimneys, breaks in gas, water, or electrical lines; and (8) location of future subsidence is not predictable. (DP)

  18. David crighton, 1942-2000: a commentary on his career and his influence on aeroacoustic theory

    NASA Astrophysics Data System (ADS)

    Ffowcs Williams, John E.

    David Crighton, a greatly admired figure in fluid mechanics, Head of the Department of Applied Mathematics and Theoretical Physics at Cambridge, and Master of Jesus College, Cambridge, died at the peak of his career. He had made important contributions to the theory of waves generated by unsteady flow. Crighton's work was always characterized by the application of rigorous mathematical approximations to fluid mechanical idealizations of practically relevant problems. At the time of his death, he was certainly the most influential British applied mathematical figure, and his former collaborators and students form a strong school that continues his special style of mathematical application. Rigorous analysis of well-posed aeroacoustical problems was transformed by David Crighton.

  19. David Barker, Buruli ulcer and the epidemiology of a neglected tropical disease.

    PubMed

    Phillips, D I W

    2015-10-01

    In 1969, David Barker, his wife and four children moved to Uganda to work at Makerere Medical School in the capital Kampala. During the 1960s, Makerere had become a research and teaching centre with an international reputation based on the work of Trowell, Burkitt, Hutt and many others who had pioneered studies explaining the disease patterns in the West Nile area on the basis of the local climate, nutrition and lifestyle. David Barker was funded by the Medical Research Council to carry out research on a poorly understood disease, Buruli ulcer, joining Scottish surgeon Wilson Carswell, who was later to achieve fame as the role model for Dr Garrigan in Giles Foden's novel The Last King of Scotland.

  20. Gold Medal Award for Life Achievement in the Application of Psychology: David W. Johnson.

    PubMed

    2016-01-01

    The American Psychological Foundation (APF) Gold Medal Awards recognize distinguished and enduring records of accomplishment in four areas of psychology. The 2016 recipient of Gold Medal Award for Life Achievement in the Application of Psychology is David W. Johnson. Dorothy W. Cantor, president of the APF, will present the APF Gold Medal Awards at the 124th Annual Convention of the American Psychological Association on August 5, 2016, at 4:00 p.m. Members of the 2016 APF Board of Trustees are Dorothy W. Cantor, president; David H. Barlow, vice president; Melba J. T. Vasquez, secretary; Richard C. McCarty, treasurer; Elisabeth R. Straus, executive vice president/executive director; Cynthia Belar; Camilla Benbow; Rosie Phillips Bingham; Connie S. Chan; Anthony Jackson; Terence M. Keane; Archie L. Turner; W. Bruce Walsh; and Bonnie Markham and Rick McGraw, APA Board of Directors liaisons. (PsycINFO Database Record PMID:27504568

  1. Gold Medal Award for Life Achievement in the Application of Psychology: David W. Johnson.

    PubMed

    2016-01-01

    The American Psychological Foundation (APF) Gold Medal Awards recognize distinguished and enduring records of accomplishment in four areas of psychology. The 2016 recipient of Gold Medal Award for Life Achievement in the Application of Psychology is David W. Johnson. Dorothy W. Cantor, president of the APF, will present the APF Gold Medal Awards at the 124th Annual Convention of the American Psychological Association on August 5, 2016, at 4:00 p.m. Members of the 2016 APF Board of Trustees are Dorothy W. Cantor, president; David H. Barlow, vice president; Melba J. T. Vasquez, secretary; Richard C. McCarty, treasurer; Elisabeth R. Straus, executive vice president/executive director; Cynthia Belar; Camilla Benbow; Rosie Phillips Bingham; Connie S. Chan; Anthony Jackson; Terence M. Keane; Archie L. Turner; W. Bruce Walsh; and Bonnie Markham and Rick McGraw, APA Board of Directors liaisons. (PsycINFO Database Record

  2. Astronaut David Wolf participates in training for contingency EVA in WETF

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Astronaut David A. Wolf participates in training for contingency extravehicular activity (EVA) for the STS-58 mission. The mission specialist was about to be submerged ito a point of neutral buoyancy in the JSC Weightless Environment Training Facility (WETF). In this view, Wolf is displaying the flexibility of his training version of the Shuttle extravehicular mobility unit (EMU) by lifting his arms above his head (31701); Wolf waves to the camera before he is submerged in the WETF (31702).

  3. Sir David K Henderson and the origins of British occupational therapy.

    PubMed

    Pentland, Duncan; Pentland, Brian

    2015-11-01

    Sir David K Henderson made several major contributions in the field of psychiatry, gaining an international reputation but, perhaps lesser known is his role in the introduction of occupational therapy in the United Kingdom. The part Henderson played in establishing occupational therapy as an aspect of his evolving approach to treating mental illness in Scotland is discussed, as is the influence he had in stimulating and supporting the early pioneers of the profession elsewhere in the UK.

  4. Dr. David Brown poses with a portrait of Ronald McNair

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the gymnasium of Ronald McNair Magnet School in Cocoa, Fla., Dr. David Brown, a NASA astronaut, poses with a portrait of NASA astronaut Ronald McNair. The portrait was presented to the school by Walt Disney World during a tribute to McNair. The school had previously been renamed for the fallen astronaut who was one of a crew of seven who lost their lives during an accident following launch of the Space Shuttle Challenger in January 1986.

  5. Joint Seismological and Geodetic Observations on David Glacier, South Victoria Land, Antarctica

    NASA Astrophysics Data System (ADS)

    Danesi, S.; Dubbini, M.; Morelli, A.; Vittuari, L.; Bannister, S.

    2006-12-01

    Ice streams play a major role in the ice mass balance and in the reckoning of the global sea level; they have therefore been the object of wide scientific interest in the last three decades. During the 21st Italian Antarctic Expedition, in the austral summer 2005-06, we deployed a joint seismographic and geodetic network in the area of the David Glacier, Southern Victoria Land. This followed a similar experiment carried out in the same area during the austral summer 2003-04 (19th Expedition) which involved the deployment of a seismographic network which recorded significant microseismicity beneath the David Glacier, primarily occurring as a few small clusters. In the latest 2006-06 deployment 7 seismographic stations and 3 GPS geodetic receivers operated continuously for a period of 3 months (November 2006-early February 2006) in an area of about 100x50 square km around the David Glacier. The seismic stations were sited on rocky outcrops around the ice flow, and were all equipped with a broad-band seismometer and a digitizer. Contemporaneous geodetic GPS measurements were made on two points located on the glacial body: the first site close to the 2003-04 epicentres and to the David Glacier ice fall, the second site on the floating Drygalski Ice Tongue. A primary master GPS receiver for the kinematic processing was installed on a benchmark located on the Hughes Bluff rock outcrop. Several analyses are planned utilising the combined data sets. These include examining the temporal evolution in earthquake magnitude and locations and also the contemporaneous observation of both seismic activity and surface kinematics of the ice stream to possibly correlate the registered microseismicity with potential surges of the glacier, eventually affected by the Ross Sea tides. Here we present some details of the two temporary networks and preliminary results and implications.

  6. Rittenhouse, David (1732-96) and Rittenhouse, Benjamin (1740-1825)

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    David was an instrument-maker and astronomer, born in Paper Mill Run, PA, self-taught, as a young man he made clocks and telescopes, introduced the use of spider's webs as cross-hairs in transit telescopes and made orreries to show planetary motions. He used his own instruments for astronomy. He worked to survey the MASON and DIXON line and taught astronomy at the University of Pennsylvania. He b...

  7. An interview with Dr Kenneth Kornman. Interview by David W Richards.

    PubMed

    Kornman, Kenneth

    2011-10-01

    Inflammation is recognized as the major underlying contributor to a number of chronic diseases, amongst them periodontitis and cardiovascular diseases. The relationship between these diseases is explored and commented on in this question-and-answer session between Ken Kornman, D.D.S., Ph.D., the editor of the Journal of Periodontology and David Richards, D.D.S., Ph.D., a former student of Dr. Kornman's. Practical suggestions and guidelines for the dentist are also examined.

  8. Spicy science: David Julius and the discovery of temperature-sensitive TRP channels

    PubMed Central

    Bautista, Diana M

    2015-01-01

    This invited biographical review covers the career of Dr. David Julius and his discovery of thermosensitive TRP channels. Dr. Julius is currently the Morris Herzstein Chair in Molecular Biology and Medicine and Professor and Chair of Physiology at the University of California, San Francisco Medical School. He is a member of the National Academy of Sciences and has received many distinguished awards for his landmark discoveries of the molecular basis of pain and thermosensation. PMID:27227012

  9. Astronauts David Scott looks at sample referred to as 'genesis rock'

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Astronauts David R. Scott, right, commander of the Apollo 15 mission, gets a close look at the sample referred to as the 'genesis rock' in the Non-Sterile Nitrogen Processing Line (NNPL) in the Lunar Receiving Laboratory (LRL) at the Manned Spacecraft Center (MSC). Scientist-Astronaut Joseph P. Allen, left, an Apollo 15 spacecraft communicator, looks on. The white-colored rock has been given the permanent identification number of 15415.

  10. University Mentality or Community College Paranoia: A Critique of Don Morgan's Reaction to David Riesman's Tentative Hypotheses.

    ERIC Educational Resources Information Center

    Vaughan, George B.

    1979-01-01

    Responds to Don Morgan's reaction (JC 502 050) to David Riesman's article, "Community Colleges: Some Tentative Hypotheses" (JC 502 056). Summarizes Riesman's major arguments and challenges Morgan's interpretations of them. (AYC)

  11. Bad-good constraints on a polarity correspondence account for the spatial-numerical association of response codes (SNARC) and markedness association of response codes (MARC) effects.

    PubMed

    Leth-Steensen, Craig; Citta, Richie

    2016-01-01

    Performance in numerical classification tasks involving either parity or magnitude judgements is quicker when small numbers are mapped onto a left-sided response and large numbers onto a right-sided response than for the opposite mapping (i.e., the spatial-numerical association of response codes or SNARC effect). Recent research by Gevers et al. [Gevers, W., Santens, S., Dhooge, E., Chen, Q., Van den Bossche, L., Fias, W., & Verguts, T. (2010). Verbal-spatial and visuospatial coding of number-space interactions. Journal of Experimental Psychology: General, 139, 180-190] suggests that this effect also arises for vocal "left" and "right" responding, indicating that verbal-spatial coding has a role to play in determining it. Another presumably verbal-based, spatial-numerical mapping phenomenon is the linguistic markedness association of response codes (MARC) effect whereby responding in parity tasks is quicker when odd numbers are mapped onto left-sided responses and even numbers onto right-sided responses. A recent account of both the SNARC and MARC effects is based on the polarity correspondence principle [Proctor, R. W., & Cho, Y. S. (2006). Polarity correspondence: A general principle for performance of speeded binary classification tasks. Psychological Bulletin, 132, 416-442]. This account assumes that stimulus and response alternatives are coded along any number of dimensions in terms of - and + polarities with quicker responding when the polarity codes for the stimulus and the response correspond. In the present study, even-odd parity judgements were made using either "left" and "right" or "bad" and "good" vocal responses. Results indicated that a SNARC effect was indeed present for the former type of vocal responding, providing further evidence for the sufficiency of the verbal-spatial coding account for this effect. However, the decided lack of an analogous SNARC-like effect in the results for the latter type of vocal responding provides an important

  12. Toxinotyping of Clostridium perfringens fecal isolates of reintroduced Père David's deer (Elaphurus davidianus) in China.

    PubMed

    Qiu, Huiling; Chen, Fu; Leng, Xinyan; Fei, Rongmei; Wang, Libo

    2014-10-01

    Clostridium perfringens is an important pathogen causing sudden death syndrome, necrotic enteritis, and gas gangrene in ruminants, especially some deer species. Père David's deer (Elaphurus davidianus) is one of the world's rare species and is an endangered and protected species in China. Some Père David's deer in the Chinese Shishou Père David's Deer Preserve died due to C. perfringens infection. We investigated the toxin types and C. perfringens enterotoxin-positive (cpe(+)) strains of isolated C. perfringens in Père David's deer in China. We collected 155 fecal samples from the Beijing Nanhaizi Père David's Deer Park and the Jiangsu Dafeng Père David's Deer National Nature Reserve between July 2010 and July 2011. Bacteria isolated using blood agar and mannitol agar plates were identified by Gram staining and nested PCR for 16S rRNA. We isolated C. perfringens from 41 fecal samples and used PCR amplification of five toxin genes to identify the toxinotypes and the cpe(+) strains of C. perfringens. Twenty-one isolates were type A, 15 were type E, and five were type D. Fifteen isolates were cpe(+) strains, including eight that were type A and seven that were type E.

  13. Comparative study on the hypoglycemic and antioxidative effects of fermented paste (doenjang) prepared from soybean and brown rice mixed with rice bran or red ginseng marc in mice fed with high fat diet.

    PubMed

    Chung, Soo Im; Rico, Catherine W; Kang, Mi Young

    2014-10-22

    The effects of fermented paste made from soybean, brown rice, or brown rice in combination with rice bran or red ginseng marc on the glucose metabolism and antioxidative defense system in high fat-fed mice were investigated. The mice were given experimental diets for eight weeks: Normal control, high fat, and high fat supplemented with soybean fermented paste, brown rice fermented paste, brown rice-rice bran fermented paste, or brown rice-red ginseng marc fermented paste. The high fat group showed markedly higher blood glucose level and erythrocyte lipid peroxidation than the normal control group. Diet supplementation of fermented paste inhibited the high fat-induced hyperglycemia and oxidative stress via regulation of the glucose-regulating and antioxidant enzymes activities. The soybean and brown rice-red ginseng marc fermented pastes were the most effective in improving the glucose metabolism and antioxidant defense status in mice under high fat diet condition. These findings illustrate that brown rice, in combination with red ginseng marc, may be useful in the development of fermented paste with strong hypoglycemic and antioxidative activities.

  14. Comparative Study on the Hypoglycemic and Antioxidative Effects of Fermented Paste (Doenjang) Prepared from Soybean and Brown Rice Mixed with Rice Bran or Red Ginseng Marc in Mice Fed with High Fat Diet

    PubMed Central

    Chung, Soo Im; Rico, Catherine W.; Kang, Mi Young

    2014-01-01

    The effects of fermented paste made from soybean, brown rice, or brown rice in combination with rice bran or red ginseng marc on the glucose metabolism and antioxidative defense system in high fat-fed mice were investigated. The mice were given experimental diets for eight weeks: Normal control, high fat, and high fat supplemented with soybean fermented paste, brown rice fermented paste, brown rice-rice bran fermented paste, or brown rice-red ginseng marc fermented paste. The high fat group showed markedly higher blood glucose level and erythrocyte lipid peroxidation than the normal control group. Diet supplementation of fermented paste inhibited the high fat-induced hyperglycemia and oxidative stress via regulation of the glucose-regulating and antioxidant enzymes activities. The soybean and brown rice-red ginseng marc fermented pastes were the most effective in improving the glucose metabolism and antioxidant defense status in mice under high fat diet condition. These findings illustrate that brown rice, in combination with red ginseng marc, may be useful in the development of fermented paste with strong hypoglycemic and antioxidative activities. PMID:25340370

  15. David's Law

    THOMAS, 113th Congress

    Rep. Jackson Lee, Sheila [D-TX-18

    2013-01-03

    01/25/2013 Referred to the Subcommittee on Crime, Terrorism, Homeland Security, And Investigations. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  16. Content changes of bitter compounds in 'Guoqing No.1' Satsuma mandarin (Citrus unshiu Marc.) during fruit development of consecutive 3 seasons.

    PubMed

    Li, Shaojie; Wang, Zhuang; Ding, Fan; Sun, Da; Ma, Zhaocheng; Cheng, Yunjiang; Xu, Juan

    2014-02-15

    The main bitter compounds (nomilin, limonin and naringin) in the fruit tissues of 'Guoqing No.1' Satsuma mandarin (Citrus unshiu Marc.) were determined throughout the fruit development of 3 consecutive growing seasons. Although fluctuating largely at the corresponding developing stages of the 3 years, the contents of these compounds in fruit tissues mostly displayed a declining trend, which implied that the rhythm of the metabolism of these bitter compounds was not consistent among years and was largely growing season dependent. Regarding their distribution, fruit flavedo might be a weak sink that contained the lowest level of naringin, while the segment membrane accumulated large amount of limonin and nomilin, which indicated a possible tissue bias pattern for biosynthesis or accumulation of those compounds. Partial correlation coefficient analysis revealed a synergistic accumulation of naringin and the two limonoid aglycones in fruit tissues during fruit development, indicating an integrated metabolism of flavonoids and limonoids.

  17. OBITUARY: Eur.Ing. Professor David Dew-Hughes in memoriam

    NASA Astrophysics Data System (ADS)

    Campbell, Archie; Dew-Hughes, Denise; Donaldson, Gordon; Palmer, Richard

    2007-06-01

    We regret to announce the death of David Dew-Hughes, the second Honorary Editor of Superconductor Science and Technology, in Autumn 2006. He was born in Manchester, the eldest of three children, attended Manchester Grammar School and took his first degree in metallurgy at Birmingham, before undertaking a Doctorate of Engineering at Yale University. After initial work for IBM on semiconductors, he returned to England as a lecturer in metallurgy at Cambridge University. There he devoted his career to superconductivity long before it became fashionable, starting a group on the properties of what we now know as type II materials, with his students Jan Evetts, Archie Campbell and Anant Narlikar. Between them they paved the way to our understanding of the magnetic vortex properties of these materials, and thus to the development of modern practical materials for superconducting magnets. Eur.Ing. Professor David Dew-Hughes 1932-2006 In 1965 he became a founding Senior Lecturer in physics at Lancaster University, moving to Brookhaven National Laboratory in 1974. His final academic post was in engineering science at Oxford University where he also held a University College Tutorial Fellowship. As long ago as 1971 David wrote an authoritative review for Reports on Progress in Physics on 'The metallurgical enhancement of type II superconductors'. Following the discovery of high-Tc superconductivity, IOP Publishing launched Superconductor Science and Technology in 1988 and he was a founder member of its Editorial Board. When Jan Evetts retired as Honorary Editor in 1992, David was the natural choice as his successor. He served a five year term and remained on the Board as Deputy Editor until the end of 2000. To mark the 10th anniversary of high-temperature superconductivity in 1997, David edited a special issue of Superconductor Science and Technology in which past and present members of the Editorial Board contributed reviews of their specialities. He noted that at that time

  18. Intraspecific host selection of Père David's deer by cattle egrets in Dafeng, China.

    PubMed

    Fernandez, Eve V; Li, Zhongqiu; Zheng, Wei; Ding, Yuhua; Sun, Daming; Che, Ye

    2014-06-01

    Studies have focused on foraging ecology of cattle egrets (Bubulcus ibis) and their selection of ungulate host species. However, few studies have been conducted at intraspecific levels, such as the sex/age class of a specific ungulate. In this study, the foraging behavior and intraspecific host selection of cattle egrets associated with Père David's deer (Elaphurus davidianus) were investigated at the Dafeng National Nature Reserve, China in summer 2011 and 2012. Egret-deer pairing status was analyzed and intraspecific host selection index was calculated. Cattle egrets preferred to feed with female deer compared with male deer and fawns. In contrast to solitary birds, cattle egrets following a deer benefited from a relatively low vigilance output, high foraging success, low energy expenditure, and high total foraging yields. These egrets also maximized benefits when they followed female deer compared with male deer and fawns. Our results further indicated that egrets likely preferred females because of the appropriate moving speed that allowed these egrets to follow and forage sufficiently and effectively. The males of Père David's deer were possibly more aggressive than the females during the rutting season, causing egrets to experience difficulty in accompaniment and feeding. Fawns were not preferred because they were usually motionless and insufficiently large to stir more insects. We did not find any behavioral differences in vigilance and feeding between juveniles and adults. Our results suggested that cattle egrets could obtain significant benefits from their association with Père David's deer, and these benefits were maximized when they followed female deer. This article is part of a Special Issue entitled: insert SI title.

  19. EDITORIAL: Van der Waals interactions in advanced materials, in memory of David C Langreth Van der Waals interactions in advanced materials, in memory of David C Langreth

    NASA Astrophysics Data System (ADS)

    Hyldgaard, Per; Rahman, Talat S.

    2012-10-01

    sufficiently close to any corrugated—and/or any smooth—surface and thus enforce a strong vdW-type adhesion; it exploits what is then essentially a contact force (dominated by the attraction exerted in the near-surface regions) to defy the pull of gravity on its own bulk. This Journal of Physics: Condensed Matter special issue is dedicated to the memory of David C Langreth. David is a dearly missed friend and mentor who inspired many of us. He was an outstanding condensed matter theorist and a scholar who greatly influenced us through his many-particle-physics based insights into density functional theory (DFT), surface science and related areas. His seminal works range from conserving formulations of interacting nonequilibrium transport [1] and formal-scattering theory [2] to an explicit formulation [3] of the exact DFT exchange-correlation energy in the adiabatic connection formula (ACF), the latter also being derived independently by Gunnarsson and Lundqvist [4]. David's portfolio also includes an analysis [5] that helped catalyze and guide the development of DFT from the local-density approximation (LDA) to the formulations of generalized gradient approximations (GGAs). Another salient contribution of David's is in the area of vdW interactions in materials. He was a key architect of the vdW density functional (vdW-DF) method [6, 7]. This method was developed in a long-standing Rutgers-Chalmers collaboration between David's group and that of Bengt I Lundqvist, later extending to a wider group of researchers on both sides of the Atlantic. Plasmons are collective excitations that depend on electron-density variation. The plasmon response can be seen as defining the nature of the LDA [4] and their description can thus also be seen as contributing to the success of GGA. The vdW-DF method is a regular constraint-based density functional (for ground-state DFT) which is derived within the ACF framework and which emphasizes the electrodynamical nature of the coupling between

  20. STS-57 PLC G. David Low, in LES, listens to egress briefing at JSC's MAIL

    NASA Technical Reports Server (NTRS)

    1993-01-01

    STS-57 Endeavour, Orbiter Vehicle (OV) 105, Payload Commander (PLC) and Mission Specialist (MS) G. David Low, wearing launch and entry suit (LES), smiles for the photographer during an emergency egress briefing. Low, along with the other STS-57 crewmembers, will participate in an emergency egress simulation in JSC's Crew Compartment Trainer (CCT) to familiarize himself with the procedures necessary in the event of an emergency during launch or landing aboard the space shuttle. The CCT is located in JSC's Mockup and Integration Laboratory (MAIL) Bldg 9NE.

  1. Sit Down with Sabin: David Schlegel: Hunting Dark Energy (LBNL Summer Lecture Series)

    SciTech Connect

    Russell, Sabin; Schlegel, David

    2011-06-22

    Lawrence Berkeley National Laboratory physicist and dark energy hunter David Schlegel chats with Sabin Russell, former San Francisco Chronicle reporter turned Berkeley Lab science writer, June 22, 2011. Their conversation is the first installment of "Sit Down With Sabin," a weekly conversation hosted by Russell. Over the course of five conversations with Berkeley Lab staff this summer, Russell will explore the ups and downs of innovative science — all without the aid of PowerPoint slides. Brought to you by Berkeley Lab Public Affairs.

  2. Memorial tribute to astrobiology pioneers Dr. David S. Mckay and academician Georgy A. Zavarzin

    NASA Astrophysics Data System (ADS)

    Rozanov, Alexei Y.; Rozhnov, Sergei V.; Pikuta, Elena V.; Hoover, Richard B.

    2013-09-01

    During the past two years, the world has lost two great pioneers of the field of Astrobiology-Dr. David Stewart McKay who worked at the NASA-Johnson Space Center in Houston, Texas, USA and Academician Georgy Alexandrovich Zavarzin of the Institute of Microbiology of the Russian Academy of Sciences and Professor of the Moscow State University in Moscow, Russia. The Volume of the Proceedings of the 2013 SPIE Instruments, Methods, and Missions for Astrobiology XVI is dedicated to the memory of these great scientists. We remember our dear friends and review some of their many important contributions to Planetary Science, Geology, Meteoritics, Microbiology and Astrobiology.

  3. Astronaut David Scott watching hammer and feather fall to lunar surface

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Astronaut David R. Scott, Apollo 15 commander, watches a geological hammer and a feather hit the lunar surface simultaneously in a test of Galileo's law of motion concerning falling bodies, as seen in this color reproduction taken from a transmission made by the RCA color television camera mounted on the Lunar Roving Vehicle. Scott released the hammer from his right hand and the feather from his left at the same instant. This experiment occured toward the end of the third and final lunar surface extravehicular activity.

  4. Johannes Kepler and David Fabricius: Their Discussion on the Nova of 1604

    NASA Astrophysics Data System (ADS)

    Granada, Miguel A.

    David Fabricius (1564-1617) was one of the most important astronomers in the period between 1596, the year of publication of Kepler's Mysterium cosmographicum, and 1609, the year of publication of the Astronomia nova.1 Kepler praised Fabricius as the most accurate observational astronomer after Tycho Brahe's death in 1601.2 Fabricius was a Reformed pastor in Ostfriesland (East Frisia), his remote natal region, and a vocational astronomer. He published nothing in the field of astronomy except for the short treatises between 1604 and 1606 concerning the nova that appeared in October 1604 in Serpentarius.

  5. Complete mitochondrial genome of the Père David's Vole, Eothenomys melanogaster (Rodentia: Arvicolinae).

    PubMed

    Chen, Shunde; Chen, Guiying; Wei, Haixue; Wang, Qiong

    2016-07-01

    The Père David's Vole, Eothenomys melanogaster belongs to subfamily Arvicolinae. It is widespread in south China, and ranges into northern Southeast Asia. In this study, the complete mitochondrial genome sequence of Eothenomys melanogaster was determined. The mitogenome is 16,331 base pairs in length. The nucleotide sequence data of 12 heavy-strand protein-coding genes of E. melanogaster and other 17 rodents were used for phylogenetic analyses. Tree constructed using Bayesian phylogenetic methods demonstrated that E. melanogaster as a sister to E. chinensis, was clustered in subfamily Arvicolinae. The monophyly of the genus Eothenomys was supported as well with Eothenomys sister to the genus Myodes.

  6. Dr. David Brown poses with students at Ronald McNair Middle School

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. David Brown (right), a NASA astronaut, poses with students in the gymnasium of Ronald McNair Magnet School in Cocoa, Fla. From left, the students are Kristin Rexford, Danitra Anderson, Dominique Smith, Fallon Davis, and Qiana Taylor. Brown was at the school to attend a tribute to NASA astronaut Ronald McNair. The school had previously been renamed for the fallen astronaut who was one of a crew of seven, who lost their lives during an accident following launch of the Space Shuttle Challenger in January 1986.

  7. Best Practices Case Study: David Weekley Homes - Eagle Springs and Waterhaven, Houston, TX

    SciTech Connect

    none,

    2011-04-01

    Case study describing David Weekley Homes, Houston Division, has qualified more than 1,240 homes for the DOE Builders Challenge. Advanced framed 2x6 walls with open headers and two-stud corners allow more room for R-20 damp sprayed cellulose wall cavity insulation that is covered with R-5 rigid XPS foam. A radiant barrier cuts heat gain in the R-38 insulated vented attics. Draft stopping at fireplace and duct chases and behind tubs, gluing sheetrock to framing, and extensive caulking make for air-tight homes at 3.0 ACH50.

  8. Pallava Bagla Receives David Perlman Award for Excellence in Science Journalism-News

    NASA Astrophysics Data System (ADS)

    Stone, Richard; Bagla, Pallava

    2011-03-01

    Pallava Bagla received the David Perlman Award at the AGU Fall Meeting Honors Ceremony, held on 15 December 2010 in San Francisco, Calif. Bagla was honored for two articles. “No sign yet of Himalayan meltdown, Indian report finds,” published in Science, explores dissent among glaciologists about a prediction that Himalayan glaciers would imminently disappear. “Himalayan glaciers melting deadline ‘a mistake,’” published by BBC News, investigates the possibility that the controversial prediction resulted from a typographical error.

  9. The wonder of their voices: The 1946 Holocaust interviews of David Boder (New York: Oxford, 2010).

    PubMed

    Rosen, Alan C

    2012-05-01

    Writing a study of psychologist David Boder's 1946 displaced persons (DP) interview project gave me a chance to further document the substantial early response to the Holocaust. This was clearly one important piece of my study, and one that was eminently straightforward. Yet much of the research on Boder's project at the point in time that I carried it out was elliptical, partly because the primary interview materials were coming to light at an astonishing pace, partly because the archive collections were virtually untapped, and partly because of the misconception of Boder and his interview project itself.

  10. Complete mitochondrial genome of the Père David's Vole, Eothenomys melanogaster (Rodentia: Arvicolinae).

    PubMed

    Chen, Shunde; Chen, Guiying; Wei, Haixue; Wang, Qiong

    2016-07-01

    The Père David's Vole, Eothenomys melanogaster belongs to subfamily Arvicolinae. It is widespread in south China, and ranges into northern Southeast Asia. In this study, the complete mitochondrial genome sequence of Eothenomys melanogaster was determined. The mitogenome is 16,331 base pairs in length. The nucleotide sequence data of 12 heavy-strand protein-coding genes of E. melanogaster and other 17 rodents were used for phylogenetic analyses. Tree constructed using Bayesian phylogenetic methods demonstrated that E. melanogaster as a sister to E. chinensis, was clustered in subfamily Arvicolinae. The monophyly of the genus Eothenomys was supported as well with Eothenomys sister to the genus Myodes. PMID:26024146

  11. Recovery of handwritten text from the diaries and papers of David Livingstone

    NASA Astrophysics Data System (ADS)

    Knox, Keith T.; Easton, Roger L., Jr.; Christens-Barry, William A.; Boydston, Kenneth

    2011-03-01

    During his explorations of Africa, David Livingstone kept a diary and wrote letters about his experiences. Near the end of his travels, he ran out of paper and ink and began recording his thoughts on leftover newspaper with ink made from local seeds. These writings suffer from fading, from interference with the printed text and from bleed through of the handwriting on the other side of the paper, making them hard to read. New image processing techniques have been developed to deal with these papers to make Livingstone's handwriting available to the scholars to read. A scan of the David Livingstone's papers was made using a twelve-wavelength, multispectral imaging system. The wavelengths ranged from the ultraviolet to the near infrared. In these wavelengths, the three different types of writing behave differently, making them distinguishable from each other. So far, three methods have been used to recover Livingstone's handwriting. These include pseudocolor (to make the different writings distinguishable), spectral band ratios (to remove text that does not change), and principal components analysis (to separate the different writings). In initial trials, these techniques have been able to lift handwriting off printed text and have suppressed handwriting that has bled through from the other side of the paper.

  12. Exploring grape marc as trove for new thermotolerant and inhibitor-tolerant Saccharomyces cerevisiae strains for second-generation bioethanol production

    PubMed Central

    2013-01-01

    Background Robust yeasts with high inhibitor, temperature, and osmotic tolerance remain a crucial requirement for the sustainable production of lignocellulosic bioethanol. These stress factors are known to severely hinder culture growth and fermentation performance. Results Grape marc was selected as an extreme environment to search for innately robust yeasts because of its limited nutrients, exposure to solar radiation, temperature fluctuations, weak acid and ethanol content. Forty newly isolated Saccharomyces cerevisiae strains gave high ethanol yields at 40°C when inoculated in minimal media at high sugar concentrations of up to 200 g/l glucose. In addition, the isolates displayed distinct inhibitor tolerance in defined broth supplemented with increasing levels of single inhibitors or with a cocktail containing several inhibitory compounds. Both the fermentation ability and inhibitor resistance of these strains were greater than those of established industrial and commercial S. cerevisiae yeasts used as control strains in this study. Liquor from steam-pretreated sugarcane bagasse was used as a key selective condition during the isolation of robust yeasts for industrial ethanol production, thus simulating the industrial environment. The isolate Fm17 produced the highest ethanol concentration (43.4 g/l) from the hydrolysate, despite relatively high concentrations of weak acids, furans, and phenolics. This strain also exhibited a significantly greater conversion rate of inhibitory furaldehydes compared with the reference strain S. cerevisiae 27P. To our knowledge, this is the first report describing a strain of S. cerevisiae able to produce an ethanol yield equal to 89% of theoretical maximum yield in the presence of high concentrations of inhibitors from sugarcane bagasse. Conclusions This study showed that yeasts with high tolerance to multiple stress factors can be obtained from unconventional ecological niches. Grape marc appeared to be an unexplored and

  13. 36th Annual David W. Smith Workshop on Malformations and Morphogenesis: Abstracts of the 2015 annual meeting.

    PubMed

    Gripp, Karen W; Adam, Margaret P; Hudgins, Louanne; Carey, John C

    2016-07-01

    The 36th Annual David W Smith Workshop on Malformations and Morphogenesis was held on August 14-19, 2015 at the Harbourtowne Conference Center in St. Michaels Maryland. The Workshop, which honors the legacy of David W Smith, brought together over 120 clinicians and researchers interested in congenital malformations and their underlying mechanisms of morphogenesis. As is the tradition of the meeting, the Workshop highlighted five themes besides mechanisms of morphogenesis: Rasopathies, Eye Malformations, Therapeutics, Prenatal Diagnosis, and Disorders of Sex Development. This Conference Report includes the abstracts presented at the 2015 Workshop. © 2016 Wiley Periodicals, Inc.

  14. The N-Reductive System Composed of Mitochondrial Amidoxime Reducing Component (mARC), Cytochrome b5 (CYB5B) and Cytochrome b5 Reductase (CYB5R) Is Regulated by Fasting and High Fat Diet in Mice

    PubMed Central

    Jakobs, Heyka H.; Mikula, Michal; Havemeyer, Antje; Strzalkowska, Adriana; Borowa-Chmielak, Monika; Dzwonek, Artur; Gajewska, Marta; Hennig, Ewa E.; Ostrowski, Jerzy; Clement, Bernd

    2014-01-01

    The mitochondrial amidoxime reducing component mARC is the fourth mammalian molybdenum enzyme. The protein is capable of reducing N-oxygenated structures, but requires cytochrome b5 and cytochrome b5 reductase for electron transfer to catalyze such reactions. It is well accepted that the enzyme is involved in N-reductive drug metabolism such as the activation of amidoxime prodrugs. However, the endogenous function of the protein is not fully understood. Among other functions, an involvement in lipogenesis is discussed. To study the potential involvement of the protein in energy metabolism, we tested whether the mARC protein and its partners are regulated due to fasting and high fat diet in mice. We used qRT-PCR for expression studies, Western Blot analysis to study protein levels and an N-reductive biotransformation assay to gain activity data. Indeed all proteins of the N-reductive system are regulated by fasting and its activity decreases. To study the potential impact of these changes on prodrug activation in vivo, another mice experiment was conducted. Model compound benzamidoxime was injected to mice that underwent fasting and the resulting metabolite of the N-reductive reaction, benzamidine, was determined. Albeit altered in vitro activity, no changes in the metabolite concentration in vivo were detectable and we can dispel concerns that fasting alters prodrug activation in animal models. With respect to high fat diet, changes in the mARC proteins occur that result in increased N-reductive activity. With this study we provide further evidence that the endogenous function of the mARC protein is linked with lipid metabolism. PMID:25144769

  15. EDITORIAL: Van der Waals interactions in advanced materials, in memory of David C Langreth Van der Waals interactions in advanced materials, in memory of David C Langreth

    NASA Astrophysics Data System (ADS)

    Hyldgaard, Per; Rahman, Talat S.

    2012-10-01

    sufficiently close to any corrugated—and/or any smooth—surface and thus enforce a strong vdW-type adhesion; it exploits what is then essentially a contact force (dominated by the attraction exerted in the near-surface regions) to defy the pull of gravity on its own bulk. This Journal of Physics: Condensed Matter special issue is dedicated to the memory of David C Langreth. David is a dearly missed friend and mentor who inspired many of us. He was an outstanding condensed matter theorist and a scholar who greatly influenced us through his many-particle-physics based insights into density functional theory (DFT), surface science and related areas. His seminal works range from conserving formulations of interacting nonequilibrium transport [1] and formal-scattering theory [2] to an explicit formulation [3] of the exact DFT exchange-correlation energy in the adiabatic connection formula (ACF), the latter also being derived independently by Gunnarsson and Lundqvist [4]. David's portfolio also includes an analysis [5] that helped catalyze and guide the development of DFT from the local-density approximation (LDA) to the formulations of generalized gradient approximations (GGAs). Another salient contribution of David's is in the area of vdW interactions in materials. He was a key architect of the vdW density functional (vdW-DF) method [6, 7]. This method was developed in a long-standing Rutgers-Chalmers collaboration between David's group and that of Bengt I Lundqvist, later extending to a wider group of researchers on both sides of the Atlantic. Plasmons are collective excitations that depend on electron-density variation. The plasmon response can be seen as defining the nature of the LDA [4] and their description can thus also be seen as contributing to the success of GGA. The vdW-DF method is a regular constraint-based density functional (for ground-state DFT) which is derived within the ACF framework and which emphasizes the electrodynamical nature of the coupling between

  16. NASA astronaut and Mir 24 crew member David Wolf after landing

    NASA Technical Reports Server (NTRS)

    1998-01-01

    NASA astronaut and Mir 24 crew member David Wolf, M.D., who was on the Russian Space Station Mir since late September 1997, greets his friend, Tammy Kruse, shortly after his return to Earth on Jan. 31. Dr. Wolf returned aboard the orbiter Endeavour with the rest of the STS-89 crew, including Commander Terrence Wilcutt; Pilot Joe Edwards Jr.; and Mission Specialists James Reilly, Ph.D.; Michael Anderson; Bonnie Dunbar, Ph.D.; and Salizhan Sharipov with the Russian Space Agency. STS-89 Mission Specialist Andrew Thomas, Ph.D., succeeded Dr. Wolf on Mir and is scheduled to remain on the Russian space station until the STS-91 Shuttle mission returns in June 1998. In addition to the docking and crew exchange, STS-89 included the transfer of science, logistical equipment and supplies between the two orbiting spacecrafts.

  17. Work plan for the radiological survey for the David Witherspoon, Incorporated, Landfill-1630 site, Knoxville, Tennessee

    SciTech Connect

    1996-07-01

    This work plan establishes the methods and requirements for performing a radiological survey at the David Witherspoon, Incorporated, Landfill-1630 Site, Knoxville, Tennessee (DWI 1630 Site) in accordance with requirements under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). The radiological survey will identify the radiological contamination level of the equipment and debris stored at the DWI 1630 Site. The data generated from the survey activities will support the decisions for characterization of the equipment/debris and aid in subsequent disposition and waste handling. The survey activities to be performed under this work plan include an equipment radiological survey, a walkover survey, and an immunoassay testing for polychlorinated biphenyls (PCBs). This work plan includes a quality assurance (QA)/quality control (QC) project plan, a health and safety (H&S) plan, and a waste management plan.

  18. Astronaut David Brown talks with team members from Lake Buena Vista, Fla

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Astronaut David Brown chats with members of the Explorers team, from Lake Buena Vista, Fla., during the FIRST (For Inspiration and Recognition of Science and Technology) Southeast Regional competition held March 9-11 in the KSC Visitor Complex Rocket Garden. Teams of high school students from all over the country are testing the limits of their imagination using robots they have designed, with the support of business and engineering professionals and corporate sponsors, to compete in a technological battle against other schools' robots. Of the 30 high school teams competing at the Southeast Regional event, 16 are Florida teams co-sponsored by NASA and KSC contractors. Local high schools participating are Astronaut, Bayside, Cocoa Beach, Eau Gallie, Melbourne, Melbourne Central Catholic, Palm Bay, Rockledge, Satellite, and Titusville.

  19. The reconstitution of political theory: David Easton, behavioralism, and the long road to system.

    PubMed

    Gunnell, John G

    2013-01-01

    During the last half of the twentieth century, the concept of system was arguably the most important concept in the theoretical repertoire of the discipline of American political science. Although systems analysis was broadly employed in the behavioral sciences, David Easton's work was particularly influential in the study of politics. This is in part because he attempted to develop a distinct account of the political system that was not theoretically subservient either to general systems theory or to conceptions of the social system such as that advanced by Talcott Parsons. Although a great deal of attention has been devoted to Easton's theory, the origins and evolution of the system concept in his work have not been carefully reconstructed and analyzed. PMID:23423865

  20. David Hartley's views on Madness: With an introduction by GE Berrios.

    PubMed

    Berrios, G E

    2015-03-01

    The psychiatric aspects of David Hartley's writings have received less attention than the rest of his work. This Classic Text deals with Section VI of his Observations on Man …, namely, the 'Imperfections of the rational Faculty'. Hartley defines madness as an imperfection of reason that can be temporary or enduring. He makes use of his model of mental functioning to differentiate between eight clinical categories of madness, each representing a different pattern of vibrations of the nerves. Hartley developed this model based on Newton's theory of vibrations and, to explain the complexity of mental acts and entities, he combined it with his own version of the mechanism of Association of Ideas borrowed from John Locke. Much work needs to be done to identify the provenance of Hartley's nosology and nosography.

  1. Remedial investigation/feasibility study for the David Witherspoon, Inc., 901 Site, Knoxville, Tennessee: Volume 1

    SciTech Connect

    1996-10-01

    This remedial investigation (RI)/feasibility study (FS) supports the selection of remedial actions for the David Witherspoon, Inc. 901 Maryville Pike Site in Knoxville, Tennessee. Operations at the site, used as a recycling center, have resulted in past, present, and potential future releases of hazardous substances in to the environment. This Site is a Tennessee Superfund site. A phased approach was planned to (1) gather existing data from previous investigations managed by the Tenn. Dept. of Environment and Conservation; (2) perform a preliminary RI, including risk assessments, and an FS with existing data to identify areas where remedial action may be necessary; (3) gather additional field data to adequately define the nature and extent of risk-based contaminants that present identifiable threats to human and/or ecological receptors; and (4) develop remedial action alternatives to reduce risks to acceptable levels.

  2. The David Jayne amendment: the story of one man's determination to improve the lives of thousands.

    PubMed

    Sokol, Eric

    2003-09-01

    Stricken by ALS at the age of 27, David Jayne slowly lost the ability to walk, to eat, to speak, and to breathe. With the assistance of home health professionals, medical technologies, and volunteers, he has managed to maintain as full a life as possible, participating in some of his children's activities and even managing, with great effort, to attend a football game. However, when he was the subject of a newspaper article, his home health coverage was dropped because he didn't meet the federal definition of "homebound." This is the story of how he took on the political establishment single-handedly, and eventually realized a victory that has the potential of helping thousands of people in similar situations to no longer be imprisoned at home. PMID:14618902

  3. "And This Is How You Shall Ask": Linguistics, Anthropology, and Education in the Work of David Smith

    ERIC Educational Resources Information Center

    Gilmore, Perry; McDermott, Ray

    2006-01-01

    This article celebrates the life and work of David M. Smith, former Council on Anthropology and Education president and founder of the University of Pennsylvania Ethnography in Education Research Forum, tracing his contributions to the fields of linguistics, anthropology, and education through the dual lens of his ten research principles and Walt…

  4. Constructing the Image of Authorial Presence: David O. Selznick and the Marketing of "Since You Went Away."

    ERIC Educational Resources Information Center

    Fenster, Mark

    1989-01-01

    Analyzes David O. Selznick's marketing campaign for the film "Since You Went Away," focusing on the promotion of the book from which the movie was adapted, and on the production of the film's souvenir program. Examines Selznick's image as author from both the auteurist and cine-structuralist perspectives. (MM)

  5. Teaching Family Communication Concepts through Family Stories: An Analysis of Stories and Rituals in David Bradley's "Harvest Home"

    ERIC Educational Resources Information Center

    Dixson, Marcia D.

    2006-01-01

    In this activity, students will be able to apply the concepts of stories and rituals to an analysis of the ritual in the short story "Harvest Home" by David Bradley, gaining understanding of how stories and rituals affect and reflect family values, power structures and identities. "Harvest Home" talks about the rituals involved in a…

  6. Theorising "Geo-Identity" and David Harvey's Space: School Choices of the Geographically Bound Middle-Class

    ERIC Educational Resources Information Center

    Rowe, Emma

    2015-01-01

    This paper draws on David Harvey's theories of absolute and relational space in order to critique geographically bound school choices of the gentrified middle-class in the City of Melbourne, Australia. The paper relies on interviews with inner-city school choosers as generated by a longitudinal ethnographic school choice study. I argue that the…

  7. Preserving Precious Instruments in Mathematics History: The Educational Museum of Teachers College and David Eugene Smith's Collection

    ERIC Educational Resources Information Center

    Murray, Diane R.

    2011-01-01

    A history is given of the Educational Museum of Teachers College, which began in 1886, and David Eugene Smith's extensive collection of mathematical tools used in the Museum's exhibits is discussed. Historic mathematical instruments including, the astrolabe, abacus and counting rods, and the slide rule are examined. The author uses digitized…

  8. Salvaging "Academic Disaster Areas": The Black College Response to Christopher Jencks and David Riesman's 1967 Harvard Educational Review Article

    ERIC Educational Resources Information Center

    Gasman, Marybeth

    2006-01-01

    In 1967, the "Harvard Educational Review" published an article entitled "The American Negro College" by Christopher Jencks and David Riesman. The article dealt a stinging blow to Black colleges--labeling them "academic disaster areas." Using a historical methodology, I show the strategic ways in which Black college leaders and the United Negro…

  9. A Philosophical Analysis of David Orr's Theory of Ecological Literacy: Biophilia, Ecojustice and Moral Education in School Learning Communities

    ERIC Educational Resources Information Center

    Mitchell, Debra B.; Mueller, Michael P.

    2011-01-01

    In his writings, David Orr claims that the US is in an "ecological crisis" and that this stems from a crisis of education. He outlines a theory of ecological literacy, a mode by which we better learn the ecology of the Earth and live in a sustainable manner. While emphasizing a shock doctrine, the diagnosis of "crisis" may be correct, but it is…

  10. Measuring Success: David Conley's College Readiness Framework and the Illinois College and Career Readiness Act. In Brief

    ERIC Educational Resources Information Center

    Baber, Lorenzo D.; Castro, Erin L.; Bragg, Debra D.

    2010-01-01

    The purpose of this brief is to understand the Illinois College and Career Readiness (CCR) Act in light of David Conley's college readiness model. Although not mentioned specifically by the Illinois statute, evaluation results gathered by the Office of Community College Research and Leadership (OCCRL) show alignment between a number of programs…

  11. The Eclipse of the Public: A Response to David Elliott's "Music Education as/for Artistic Citizenship"

    ERIC Educational Resources Information Center

    Woodford, Paul

    2014-01-01

    This paper is an invited response to a one published by David Elliott in The Music Educator in 2012 in which music teachers were enjoined to encourage children to use music's expressive power as a political tool in pursuit of social justice. While in agreement with him that this can be an appropriate use of music, there is a curious avoidance…

  12. Teacher as Actor--Henry David Thoreau--From Room One-Eleven to Walden Pond and Beyond.

    ERIC Educational Resources Information Center

    Barto, David

    To help maintain class interest in the important themes addressed in "Walden" and "The Duties of Civil Disobedience," a high school English teacher has presented a dramatic monologue as Henry David Thoreau to his students. After much library research, the teacher used some of the props characteristic of the author, such as a walking stick and a…

  13. The Repositioning of Language Centres: An Appreciation of David Ingram's "Language Centres--Their Roles, Functions and Management"

    ERIC Educational Resources Information Center

    Sussex, Roland

    2004-01-01

    David Ingram's "Language Centres" (2001) offers a descriptive and analytical study of meta-centres, their constitution, operation and engagement with their constituencies. This article is a combination of a review and an appreciation of Ingram's study, and--benefiting from the latitude offered by the genre of the review article--a set of…

  14. Rate, Probability and Matching: Comments on "The Identities Hidden in the Matching Laws, and Their Uses" by David Thorne

    ERIC Educational Resources Information Center

    Rachlin, Howard; Locey, Matthew L.

    2010-01-01

    David Thorne's (2010) article, "The Identities Hidden In The Matching Laws, And Their Uses" performs a valuable service in pointing out alternative expressions of matching. However, some identities tend to obscure rather than illuminate empirical relationships. Three such problematic instances are discussed: interresponse time as a function of…

  15. Values, Leadership, and Quality: The Administration of Higher Education. The David D. Henry Lectures, 1979-1985.

    ERIC Educational Resources Information Center

    1990

    This book contains five lectures, delivered as part of the David D. Henry lecture series, whose common theme revolved around broadly defined issues related to the administration of higher education. The first lecture, "Quality and Equality in Health Professions Education and Service" (Lloyd C. Elam), argues that quality and equality in the…

  16. The David and Goliath principle: cultural, ideological, and attitudinal underpinnings of the normative protection of low-status groups from criticism.

    PubMed

    Jeffries, Carla H; Hornsey, Matthew J; Sutton, Robbie M; Douglas, Karen M; Bain, Paul G

    2012-08-01

    Two studies documented the "David and Goliath" rule--the tendency for people to perceive criticism of "David" groups (groups with low power and status) as less normatively permissible than criticism of "Goliath" groups (groups with high power and status). The authors confirmed the existence of the David and Goliath rule across Western and Chinese cultures (Study 1). However, the rule was endorsed more strongly in Western than in Chinese cultures, an effect mediated by cultural differences in power distance. Study 2 identified the psychological underpinnings of this rule in an Australian sample. Lower social dominance orientation (SDO) was associated with greater endorsement of the rule, an effect mediated through the differential attribution of stereotypes. Specifically, those low in SDO were more likely to attribute traits of warmth and incompetence to David versus Goliath groups, a pattern of stereotypes that was related to the protection of David groups from criticism.

  17. The East Pacific Rise and its flanks 8 18° N: History of segmentation, propagation and spreading direction based on SeaMARC II and Sea Beam studies

    NASA Astrophysics Data System (ADS)

    MacDonald, Ken C.; Fox, Paul J.; Miller, Steve; Carbotte, Suzanne; Edwards, Margo H.; Eisen, Mark; Fornari, Daniel J.; Perram, Laura; Pockalny, Rob; Scheirer, Dan; Tighe, Stacey; Weiland, Charles; Wilson, Doug

    1992-12-01

    SeaMARC II and Sea Beam bathymetric data are combined to create a chart of the East Pacific Rise (EPR) from 8°N to 18°N reaching at least 1 Ma onto the rise flanks in most places. Based on these data as well as SeaMARC II side scan sonar mosaics we offer the following observations and conclusions. The EPR is segmented by ridge axis discontinuities such that the average segment lengths in the area are 360 km for first-order segments, 140 km for second-order segments, 52 km for third-order segments, and 13 km for fourth-order segments. All three first-order discontinuities are transform faults. Where the rise axis is a bathymetric high, second-order discontinuities are overlapping spreading centers (OSCs), usually with a distinctive 3:1 overlap to offset ratio. The off-axis discordant zones created by the OSCs are V-shaped in plan view indicating along axis migration at rates of 40 100 mm yr-1. The discordant zones consist of discrete abandoned ridge tips and overlap basins within a broad wake of anomalously deep bathymetry and high crustal magnetization. The discordant zones indicate that OSCs have commenced at different times and have migrated in different directions. This rules out any linkage between OSCs and a hot spot reference frame. The spacing of abandoned ridges indicates a recurrence interval for ridge abandonment of 20,000 200,000 yrs for OSCs with an average interval of approximately 100,000 yrs. Where the rise axis is a bathymetric low, the only second-order discontinuity mapped is a right-stepping jog in the axial rift valley. The discordant zone consists of a V-shaped wake of elongated deeps and interlocking ridges, similar to the wakes of second-order discontinuities on slow-spreading ridges. At the second-order segment level, long segments tend to lengthen at the expense of neighboring shorter segments. This can be understood if segments can be approximated by cracks, because the propagation force at a crack tip is directly proportional to crack

  18. Effect of different postharvest temperatures on the accumulation of sugars, organic acids, and amino acids in the juice sacs of Satsuma mandarin (Citrus unshiu Marc.) fruit.

    PubMed

    Matsumoto, Hikaru; Ikoma, Yoshinori

    2012-10-01

    To elucidate the effect of different postharvest temperatures on the accumulation of sugars, organic acids, and amino acids and to determine the best temperature to minimize their postharvest change, their content after harvest was investigated at 5, 10, 20, and 30 °C for 14 days in the juice sacs of Satsuma mandarin (Citrus unshiu Marc. cv. Aoshima-unshiu) fruit. In all sugars, the changes were negligible at all temperatures. Organic acids decreased slightly at all temperatures, with the exception of malic acid at 30 °C, which increased slightly. Two amino acids, ornithine and glutamine, increased at 5 °C, but they did not increase at other temperatures. In 11 amino acids (phenylalanine, tryptophan, tyrosine, isoleucine, leucine, valine, threonine, lysine, methionine, histidine, and γ-amino butyric acid), the content was higher at 20 and 30 °C than at other temperatures. Thus, the content of amino acids was more variable than that of sugars and organic acids in response to temperatures. Moreover, amino acids responded to temperature differently: two amino acids were cold responsive, and 11 were heat-responsive. The best temperature to minimize the postharvest changes in amino acid profiles in the juice sacs of Aoshima-unshiu was 10 °C. The responsiveness to temperatures in two cold-responsive (ornithine and glutamine) and five heat-responsive (phenylalanine, tryptophan, valine, lysine, and histidine) amino acids was conserved among three different Satsuma mandarin cultivars, Aoshima-unshiu (late-maturing cultivar), Silverhill (midmaturing cultivar), and Miyagawa-wase (early-maturing cultivar). The metabolic responsiveness to temperature stress was discussed on the basis of the changes in the amino acid profile.

  19. Response to the Point of View of Gregory B. Pauly, David M. Hillis, and David C. Cannatella, by the Anuran Subcommittee of the SSAR/HL/ASIH Scientific and Standard English Names List

    USGS Publications Warehouse

    Frost, Darrel R.; McDiarmid, Roy W.; Mendelson, Joseph R.

    2009-01-01

    The Point of View by Gregory Pauly, David Hillis, and David Cannatella misrepresents the motives and activities of the anuran subcommittee of the Scientific and Standard English Names Committee, contains a number of misleading statements, omits evidence and references to critical literature that have already rejected or superseded their positions, and cloaks the limitations of their nomenclatural approach in ambiguous language. Their Point of View is not about promoting transparency in the process of constructing the English Names list, assuring that its taxonomy is adequately reviewed, or promoting nomenclatural stability in any global sense. Rather, their Point of View focuses in large part on a single publication, The Amphibian Tree of Life, which is formally unrelated to the Standard English Names List, and promotes an approach to nomenclature mistakenly asserted by them to be compatible with both the International Code of Zoological Nomenclature and one of its competitors, the PhyloCode.

  20. David Triggle: Research collaborations and scientific exchanges with the China Pharmaceutical University, Nanjing, China.

    PubMed

    Dai, De-Zai

    2015-11-15

    Over the period 1995-2012, David Triggle was a frequent visitor to the China Pharmaceutical University in Nanjing, China making many important contributions that enhanced the activities of the Research Division of Pharmacology at the University. In addition to providing collegial advice and facilitating interactions with the international pharmacological community, Professor Triggle's international reputation as a thought leader in the field of ion channel research and drug discovery provided important insights into the potential pathophysiological and therapeutic effects of targeting ion channels. This included the L-type calcium channel and the outward delayed rectified potassium currents of rapid (IKr) and slow (IKs) components in the myocardium. The Nanjing research team had been particularly interested in ion channel dysfunction in the context of cardiac arrhythmias, remodeling and drug discovery. With Professor Triggle's assistance, the relationship between an increase in ICa.L and other biological events including an enhancement of IKr and IKr currents, NADPH oxidase and endothelin receptor activation, down regulation of calcium modulating protein FKBP12.6, sarco/endoplasmic reticulum Ca(2+)ATPse (SERCA2A) and calsequens 2 (CASQ2), calcium leak at the diastole and endoplasmic reticulum stress, were evaluated and are discussed. Additionally, the organization of several international symposia was greatly enhanced by input from Professor Triggle as were the published research manuscripts in international pharmacology journals. During his association with the China Pharmaceutical University, Professor Triggle aided in enhancing the scientific standing of the Pharmacology department and was a highly effective ambassador for international research cooperation.

  1. Plasticity, stability, and yield: the origins of Anthony David Bradshaw's model of adaptive phenotypic plasticity.

    PubMed

    Peirson, B R Erick

    2015-04-01

    Plant ecologist Anthony David Bradshaw's account of the evolution of adaptive phenotypic plasticity remains central to contemporary research aimed at understanding how organisms persist in heterogeneous environments. Bradshaw suggested that changes in particular traits in response to specific environmental factors could be under direct genetic control, and that natural selection could therefore act directly to shape those responses: plasticity was not "noise" obscuring a genetic signal, but could be specific and refined just as any other adaptive phenotypic trait. In this paper, I document the contexts and development of Bradshaw's investigation of phenotypic plasticity in plants, including a series of unreported experiments in the late 1950s and early 1960s. Contrary to the mythology that later emerged around Bradshaw's ideas, Bradshaw was engaged in a serious and sustained empirical research program concerning plasticity in the 1950s and 1960s that went far beyond a single review paper. Moreover, that work was not isolated, but was surrounded by an already rich theoretical discourse and a substantial body of empirical research concerning the evolution of developmental plasticity and stability. Bradshaw recast the problem of how to understand (and control) plasticity and stability within an epistemic framework focused on genetic differences and natural selection. PMID:25641217

  2. David J. Triggle: Medicinal chemistry, to pharmacology, calcium channels, and beyond.

    PubMed

    Walker, Michael J A

    2015-11-15

    David Triggle's scientific career began as a chemist, went through medicinal chemistry into pharmacology, and finally on to somewhat more philosophical interests in later years. It was a career marked by many contributions to all of those aspects of science. Chief amongst his many contributions, in addition to those in medicinal chemistry, was his work on the drugs known as calcium ion channel blockers or (calcium antagonists). In the calcium ion channel field he was a particularly instrumental figure in sorting out the mechanisms, actions and roles of the class of calcium channel blockers, known chemical and pharmacologically as the dihydropyridines (DHPs) in particular, as well as other calcium blockers of diverse structures. During the course of a long career, and extensive journeys into medicinal chemistry and pharmacology, he published voluminously in terms of papers, reviews, conference proceedings and books. Notably, many of his papers often had limited authorship where, as senior author it reflected his deep involvement in all aspects of the reported work. His work always helped clarify the field while his incisive reviews, together with his role in coordinating and running scientific meetings, were a great help in clarifying and organizing various fields of study. He has had a long and illustrious career, and is wellknown in the world of biomedical science; his contributions are appreciated, and well recognized everywhere. The following article attempts to chart a path through his work and contributions to medicinal chemistry, pharmacology, science, academia and students.

  3. Integration of approaches in David Wake's model-taxon research platform for evolutionary morphology.

    PubMed

    Griesemer, James

    2013-12-01

    What gets integrated in integrative scientific practices has been a topic of much discussion. Traditional views focus on theories and explanations, with ideas of reduction and unification dominating the conversation. More recent ideas focus on disciplines, fields, or specialties; models, mechanisms, or methods; phenomena, problems. How integration works looks different on each of these views since the objects of integration are ontologically and epistemically various: statements, boundary conditions, practices, protocols, methods, variables, parameters, domains, laboratories, and questions all have their own structures, functions and logics. I focus on one particular kind of scientific practice, integration of "approaches" in the context of a research system operating on a special kind of "platform." Rather than trace a network of interactions among people, practices, and theoretical entities to be integrated, in this essay I focus on the work of a single investigator, David Wake. I describe Wake's practice of integrative evolutionary biology and how his integration of approaches among biological specialties worked in tandem with his development of the salamanders as a model taxon, which he used as a platform to solve, re-work and update problems that would not have been solved so well by non-integrative approaches. The larger goal of the project to which this paper contributes is a counter-narrative to the story of 20th century life sciences as the rise and march of the model organisms and decline of natural history.

  4. David Blackwell’s Forty Years in the Idaho Desert, The Foundation for 21st Century Geothermal Research

    SciTech Connect

    McLing, Travis; McCurry, Mike; Cannon, Cody; Neupane, Ghanashyam; Wood, Thomas; Podgorney, Robert; Welhan, John; Mines, Greg; Mattson, Earl; Wood, Rachel; Palmer, Carl

    2015-04-01

    Dr. David Blackwell has had a profound influence on geo-thermal exploration and R&D in Idaho. Forty years have elapsed since the first Southern Methodist University (SMU) temperature logging truck rolled onto the high desert in Southern Idaho, yet even after so much time has elapsed, most recent and ongoing geothermal R&D can trace its roots to the foundational temperature studies led by Dr. Blackwell. We believe that the best way to honor any scientist is to see their work carried forward by others. As this paper demonstrates, it has been an easy task to find a host of Idaho researchers and students eager to contribute to this tribute paper. We organize this paper by ongoing or recent projects that continue to benefit left to Idaho by Dr. David Blackwell.

  5. Affirming Psychological Science--For Students, Teachers, and the Larger World: An Interview With David G. Myers

    ERIC Educational Resources Information Center

    Miller, Jr., Harold L.

    2005-01-01

    David G. Myers received a BA in chemistry, magna cum laude from Whitworth College and an MA and PhD in psychology from the University of Iowa. Since 1982 he has been the John Dirk Werkman Professor of Psychology at Hope College. He is best known for his authorship of Psychology (2004), now in its 7th edition, and Social Psychology (2005a), now in…

  6. STS-57 MS and PLC G. David Low examines CGBA pack in OV-105's SPACEHAB module

    NASA Technical Reports Server (NTRS)

    1993-01-01

    STS-57 Mission Specialist (MS) and Payload Commander (PLC) G. David Low examines Commercial Generic Bioprocessing Apparatus (CGBA) group activation pack (GAP) incubator while in front of the SPACEHAB-01 (Commercial Middeck Augmentation Module (CMAM)) aft lockers. Low has temporarily removed the GAP from its locker location. Crewmembers are conducting a variety of experiments inside SPACEHAB-01 module which is positioned in the payload bay (PLB) of the Earth-orbiting Endeavour, Orbiter Vehicle (OV) 105.

  7. STS-32 MS G. David Low dons LES CCA in KSC LC Pad 39A white room

    NASA Technical Reports Server (NTRS)

    1990-01-01

    STS-32 Mission Specialist (MS) G. David Low, wearing launch and entry suit (LES), fastens strap on LES communications carrier assembly (CCA) cap in the white room on the orbiter access arm at Kennedy Space Center (KSC) Launch Complex (LC) Pad 39A. Technicians oversee the suiting operations. MS Marsha S. Ivins sits next to Low. When fully equipped, Low and Ivins will enter Columbia, Orbiter Vehicle (OV) 102, side hatch which appears in the background.

  8. The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists

    PubMed Central

    Huang, Da Wei; Sherman, Brad T; Tan, Qina; Collins, Jack R; Alvord, W Gregory; Roayaei, Jean; Stephens, Robert; Baseler, Michael W; Lane, H Clifford; Lempicki, Richard A

    2007-01-01

    The DAVID Gene Functional Classification Tool uses a novel agglomeration algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules. This organization is accomplished by mining the complex biological co-occurrences found in multiple sources of functional annotation. It is a powerful method to group functionally related genes and terms into a manageable number of biological modules for efficient interpretation of gene lists in a network context. PMID:17784955

  9. Evaluation of MLC leaf positioning accuracy for static and dynamic IMRT treatments using DAVID in vivo dosimetric system.

    PubMed

    Karagoz, Gulay; Zorlu, Faruk; Yeginer, Mete; Yildiz, Demet; Ozyigit, Gokhan

    2016-01-01

    Accuracy and precision of leaf positioning in multileaf collimators (MLCs) are significant factors for the accuracy of IMRT treatments. This study aimed to inves-tigate the accuracy and repeatability of the MLC leaf positioning via the DAVID invivo dosimetric system for dynamic and static MLC systems. The DAVID system was designed as multiwire transmission ionization chamber which is placed in accessory holder of linear accelerators. Each wire of DAVID system corresponds to a MLC leaf-pair to verify the leaf positioning accuracy during IMRT treatment and QA. In this study, verifications of IMRT plans of five head and neck (H&N) and five prostate patients treated in a Varian DHX linear accelerator with 80-leaf MLC were performed using DAVID system. Before DAVID-based dosimetry, Electronics Portal Imaging Device (EPID) and PTW 2D ARRAY dosimetry system were used for 2D verification of each plan. The measurements taken by DAVID system in the first day of the treatments were used as reference for the following measurements taken over the next four weeks. The deviations in leaf positioning were evaluated by "Total Deviation (TD)" parameter calculated by DAVID software. The delivered IMRT plans were originally prepared using dynamic MLC method. The same plans were subsequently calculated based on static MLC method with three different intensity levels of five (IL5), 10 (IL10) and 20 (IL20) in order to compare the performances of MLC leaf positioning repeatability for dynamic and static IMRT plans. The leaf positioning accuracy is also evaluated by analyzing DynaLog files based on error histograms and root mean square (RMS) errors of leaf pairs' positions. Moreover, a correlation analysis between simultaneously taken DAVID and EPID measurements and DynaLog file recordings was subsequently performed. In the analysis of DAVID outputs, the overall deviations of dynamic MLC-based IMRT calculated from the deviations of the four weeks were found as 0.55% ± 0.57% and 1.48% ± 0

  10. Evaluation of MLC leaf positioning accuracy for static and dynamic IMRT treatments using DAVID in vivo dosimetric system.

    PubMed

    Karagoz, Gulay; Zorlu, Faruk; Yeginer, Mete; Yildiz, Demet; Ozyigit, Gokhan

    2016-03-08

    Accuracy and precision of leaf positioning in multileaf collimators (MLCs) are significant factors for the accuracy of IMRT treatments. This study aimed to inves-tigate the accuracy and repeatability of the MLC leaf positioning via the DAVID invivo dosimetric system for dynamic and static MLC systems. The DAVID system was designed as multiwire transmission ionization chamber which is placed in accessory holder of linear accelerators. Each wire of DAVID system corresponds to a MLC leaf-pair to verify the leaf positioning accuracy during IMRT treatment and QA. In this study, verifications of IMRT plans of five head and neck (H&N) and five prostate patients treated in a Varian DHX linear accelerator with 80-leaf MLC were performed using DAVID system. Before DAVID-based dosimetry, Electronics Portal Imaging Device (EPID) and PTW 2D ARRAY dosimetry system were used for 2D verification of each plan. The measurements taken by DAVID system in the first day of the treatments were used as reference for the following measurements taken over the next four weeks. The deviations in leaf positioning were evaluated by "Total Deviation (TD)" parameter calculated by DAVID software. The delivered IMRT plans were originally prepared using dynamic MLC method. The same plans were subsequently calculated based on static MLC method with three different intensity levels of five (IL5), 10 (IL10) and 20 (IL20) in order to compare the performances of MLC leaf positioning repeatability for dynamic and static IMRT plans. The leaf positioning accuracy is also evaluated by analyzing DynaLog files based on error histograms and root mean square (RMS) errors of leaf pairs' positions. Moreover, a correlation analysis between simultaneously taken DAVID and EPID measurements and DynaLog file recordings was subsequently performed. In the analysis of DAVID outputs, the overall deviations of dynamic MLC-based IMRT calculated from the deviations of the four weeks were found as 0.55% ± 0.57% and 1.48% ± 0

  11. Spotlight: David Wood, MD, MSc, FRCP, FESC. A journey from a remote area of Scotland to the capital of the United Kingdom. Interview by Hannah Brown.

    PubMed

    Wood, David

    2007-12-01

    The death of an ambulance driver prompted David Wood, MD, MSc, FRCP, FESC, now Garfield Weston Professor of Cardiovascular Medicine at Imperial College, London, United Kingdom, to pursue cardiology as a career.

  12. David L. Parkhurst as the recipient of the 2012 O.E. Meinzer Award of the Hydrogeology Division of the Geological Society of America

    USGS Publications Warehouse

    Glynn, Pierre D.

    2012-01-01

    Describes the impact of USGS scientist David Parkhurst's influential contributions to the fields of aqueous geochemistry and hydrogeology. Parkhurst is the recipient of the 2012 O.E. Meinzer award of the Geological Society of America's Hydrogeology Division.

  13. A rendezvous with the queen of ion channels: Three decades of ion channel research by David T Yue and his Calcium Signals Laboratory

    PubMed Central

    Dick, Ivy E; Limpitikul, Worawan B; Niu, Jacqueline; Banerjee, Rahul; Issa, John B; Ben-Johny, Manu; Adams, Paul J; Kang, Po Wei; Lee, Shin Rong; Sang, Lingjie; Yang, Wanjun; Babich, Jennifer; Zhang, Manning; Bazazzi, Hojjat; Yue, Nancy C; Tomaselli, Gordon F

    2016-01-01

    David T. Yue was a renowned biophysicist who dedicated his life to the study of Ca2+ signaling in cells. In the wake of his passing, we are left not only with a feeling of great loss, but with a tremendous and impactful body of work contributed by a remarkable man. David's research spanned the spectrum from atomic structure to organ systems, with a quantitative rigor aimed at understanding the fundamental mechanisms underlying biological function. Along the way he developed new tools and approaches, enabling not only his own research but that of his contemporaries and those who will come after him. While we cannot hope to replicate the eloquence and style we are accustomed to in David's writing, we nonetheless undertake a review of David's chosen field of study with a focus on many of his contributions to the calcium channel field. PMID:26176690

  14. Structural evolution of the East Pacific Rise axis from 13°10'N to 10°35'N: interpretations from SeaMARC I data

    NASA Astrophysics Data System (ADS)

    Crane, Kathleen

    1987-05-01

    In 1983 the SeaMARC I and the Sea Beam systems imaged the East Pacific Rise (EPR) and the Clipperton Transform Fault from 13°10'N to 9°50'N revealing both magmatic and tectonic segmentation along the rise axis. Tectonic segments are defined by an undulating axial zone of extension which widens and narrows at an average wavelength of 45 km. In addition, axial fissure-fault-density and -length curves reveal wavelengths of 30 and 56 km. The narrowest axial zones, < 0.5 km in width, correspond to regions of hydrothermal activity and are located atop regional morphologic highs quasi-harmonically spaced at 155 km. These highs define the major magma centers on the rise axis about which seamounts cluster. Superimposed on the intermediate-wavelength highs are smaller highs (from 10 to 50 km in length) which are truncated by overlapping spreading centers (OSC's) at their distal edges. The rise axis widens near OSC's while it narrows and disappears near the Clipperton Transform Fault suggesting that transforms and OSC's have different origins. Imagery on and adjacent to a few OSC's reveals that in some cases OSC's migrate along the axis forming relict off-axial structural traces at oblique angles (285°-330°) to the axis. Off-axial fault density and length curves have wavelengths similar to the axial curves. However, fault densities to the west of the axis are somewhat antisymmetric to fissure-fault densities on the axis. In contrast, faults to the east of the axis nearly mimic fissure-fault density and length curves on the axis suggesting that the fracture pattern is controlled by the state of deviatoric stress in the adjacent Cocos Plate to the east. The data suggest that large deep-seated magma diapirs may dominate the magmatic segmentation of the EPR generating dynamically supported 155 km wavelength highs. Smaller, shallower magma cupulas may rise as fingers to the seafloor above the large diapirs. Where the magma erupts may be a factor of the thin skin tectonic

  15. A tribute to Charles David Kelman MD: ophthalmologist, inventor and pioneer of phacoemulsification surgery.

    PubMed

    Pandey, Suresh K; Milverton, E John; Maloof, Anthony J

    2004-10-01

    Charles David Kelman was born in Brooklyn, New York, USA, on 23 May 1930 and passed away in Boca Raton, Florida, USA, on 1 June 2004 at the age of 74 years after a long battle with cancer. He received a Bachelor of Science degree from Tufts University in 1950 and completed medical studies at the University of Geneva, Switzerland, in 1956. He was Clinical Professor of Ophthalmology at New York Medical College and an Attending Surgeon at New York Eye and Ear Infirmary and Manhattan Eye, Ear and Throat Hospital. Although a prolific inventor, he will be best remembered for developing phacoemulsification, following his realization while sitting in a dentist's chair, that ultrasonic vibrations could be used to emulsify the aged crystalline lens through a very small incision. His pioneering work revolutionized cataract surgery. He also pioneered cryo-extraction of cataracts, the use of freezing for the repair of retinal detachments and designed numerous ophthalmic instruments and intraocular lenses. Dr Kelman received numerous awards, including the American Academy of Ophthalmology Achievement Award (1970), the Ridley Medal from the International Congress of Ophthalmology (1990), and the Inventor of the Year Award from The New York Patent, Trademark and Copyright Law Association (1992). Most recently (2003), Dr Kelman was honoured by the American Academy of Ophthalmology with the Laureate Recognition award. Dr Kelman was also an accomplished Broadway producer, composer and jazz saxophonist. With his demise, the ophthalmic and medical community lost a famed inventor with multifaceted talents and one of the great ophthalmologists of the twentieth century.

  16. Marshall Amateur Club experiment (MARCE)

    NASA Technical Reports Server (NTRS)

    Stluka, E. F.

    1984-01-01

    The integration of the Get Away Special (GAS) payload for the space shuttle is discussed in terms of systems design. In addition to the primary power, control, and distribution networks to electrically integrate the spaceborne experiments, an instrument measuring system, a data system, and a radio frequency downlink system were designed. A brief review of these systems is given.

  17. "implicate Order" and the Good Life: Applying David Bohm's Ontology in Human World

    NASA Astrophysics Data System (ADS)

    Ravn, Ib.

    In an attempt to formulate a coherent view of quantum reality, the theoretical physicist David Bohm has proposed a new concept of order to supplement the mechanistic Cartesian order of traditional physics. The "implicate" order is a subtler and deeper order that emphasizes "unbroken wholeness in flowing movement," in contrast to the coarser and more superficial, "explicate" Cartesian order of distinct phenomena. This dissertation attempts to develop a meaning for the idea of implicate order in the world of human experience. First is offered an account of some evolutionary episodes in terms of implicate and explicate order which draws on compatible work in cosmology, embryogenesis, visual perception, brain memory, decision making and phenomenology. Two important characteristics of the implicate order are then identified: in an implicate order, the whole is enfolded (or represented) in its parts; and all parts render different perspectives of the whole. Using arguments from decision making, the study of "flow" in human consciousness, and a model of skill acquisition, it is suggested that these characteristics manifest themselves in the human world as the "unity experience" and the "diversity experience," respectively. The former is the experience that a given part of one's life reveals a larger wholeness or unity; the subject-object distinction is transcended and one becomes absorbed in the flow of whatever activity is pursued. The latter is a deep appreciation of the diversity of ways in which people may seek the unity experience. These experiences are proposed as general values: social and psychological conditions ought to be such that these experiences are enhanced in all people. A two-by-two matrix of the two experiences demonstrates the danger of pursuing one to the exclusion of the other. The experience of unity without diversity turns into absolutism, the insistence that one's chosen activities or beliefs are the only right ones. The experience of diversity

  18. David Grant Medical Center energy use baseline and integrated resource assessment

    SciTech Connect

    Richman, E.E.; Hoshide, R.K.; Dittmer, A.L.

    1993-04-01

    The US Air Mobility Command (AMC) has tasked Pacific Northwest Laboratory (PNL) with supporting the US Department of Energy (DOE) Federal Energy Management Program's (FEMP) mission to identify, evaluate, and assist in acquiring all cost-effective energy resource opportunities (EROs) at the David Grant Medical Center (DGMC). This report describes the methodology used to identify and evaluate the EROs at DGMC, provides a life-cycle cost (LCC) analysis for each ERO, and prioritizes any life-cycle cost-effective EROs based on their net present value (NPV), value index (VI), and savings to investment ratio (SIR or ROI). Analysis results are presented for 17 EROs that involve energy use in the areas of lighting, fan and pump motors, boiler operation, infiltration, electric load peak reduction and cogeneration, electric rate structures, and natural gas supply. Typical current energy consumption is approximately 22,900 MWh of electricity (78,300 MBtu), 87,600 kcf of natural gas (90,300 MBtu), and 8,300 gal of fuel oil (1,200 MBtu). A summary of the savings potential by energy-use category of all independent cost-effective EROs is shown in a table. This table includes the first cost, yearly energy consumption savings, and NPV for each energy-use category. The net dollar savings and NPV values as derived by the life-cycle cost analysis are based on the 1992 federal discount rate of 4.6%. The implementation of all EROs could result in a yearly electricity savings of more than 6,000 MWh or 26% of current yearly electricity consumption. More than 15 MW of billable load (total billed by the utility for a 12-month period) or more than 34% of current billed demand could also be saved. Corresponding natural gas savings would be 1,050 kcf (just over 1% of current consumption). Total yearly net energy cost savings for all options would be greater than $343,340. This value does not include any operations and maintenance (O M) savings.

  19. David Grant Medical Center energy use baseline and integrated resource assessment

    SciTech Connect

    Richman, E.E.; Hoshide, R.K.; Dittmer, A.L.

    1993-04-01

    The US Air Mobility Command (AMC) has tasked Pacific Northwest Laboratory (PNL) with supporting the US Department of Energy (DOE) Federal Energy Management Program`s (FEMP) mission to identify, evaluate, and assist in acquiring all cost-effective energy resource opportunities (EROs) at the David Grant Medical Center (DGMC). This report describes the methodology used to identify and evaluate the EROs at DGMC, provides a life-cycle cost (LCC) analysis for each ERO, and prioritizes any life-cycle cost-effective EROs based on their net present value (NPV), value index (VI), and savings to investment ratio (SIR or ROI). Analysis results are presented for 17 EROs that involve energy use in the areas of lighting, fan and pump motors, boiler operation, infiltration, electric load peak reduction and cogeneration, electric rate structures, and natural gas supply. Typical current energy consumption is approximately 22,900 MWh of electricity (78,300 MBtu), 87,600 kcf of natural gas (90,300 MBtu), and 8,300 gal of fuel oil (1,200 MBtu). A summary of the savings potential by energy-use category of all independent cost-effective EROs is shown in a table. This table includes the first cost, yearly energy consumption savings, and NPV for each energy-use category. The net dollar savings and NPV values as derived by the life-cycle cost analysis are based on the 1992 federal discount rate of 4.6%. The implementation of all EROs could result in a yearly electricity savings of more than 6,000 MWh or 26% of current yearly electricity consumption. More than 15 MW of billable load (total billed by the utility for a 12-month period) or more than 34% of current billed demand could also be saved. Corresponding natural gas savings would be 1,050 kcf (just over 1% of current consumption). Total yearly net energy cost savings for all options would be greater than $343,340. This value does not include any operations and maintenance (O&M) savings.

  20. Jacques-Louis David's tumour: an opportunity to study the natural history of a pleomorphic adenoma of the parotid gland.

    PubMed

    Wine, Humphrey; Baum, Michael

    2008-12-01

    The great artist and one-time revolutionary, Jacques-Louis David died in 1825. The cause of his death has been open to speculation. An extraordinary sequence of portraits of the artist describes his transition from handsome middle age to a deformed old man. During this phase a swelling appears at the angle of his left jaw and over a period of 20 years a facial palsy can be diagnosed. We submit that this evidence suggests that malignant transformation of a pleomorphic adenoma of the parotid gland was the proximal cause of his death.

  1. RCRA Summary Document for the David Witherspoon 1630 Site, Knoxville, Tennessee

    SciTech Connect

    Pfeffer, J.

    2008-06-10

    The 48-acre David Witherspoon, Inc. (DWI) 1630 Site operated as an unregulated industrial landfill and scrap yard. The Tennessee Division of Superfund (TDSF) closed the landfill in 1974. During the period of operation, the site received solid and liquid wastes from salvage and industrial operations. The site consists of five separate tracts of land including a small portion located across the Norfolk Southern Railroad track. The landfill occupies approximately 5 acres of the site, and roughly 20 acres of the 48 acres contains surface and buried debris associated with the DWI dismantling business operation. Beginning in 1968, the state of Tennessee licensed DWI to receive scrap metal at the DWI 1630 Site, contaminated with natural uranium and enriched uranium (235U) not exceeding 0.1 percent by weight (TDSF 1990). The U.S. Department of Energy (DOE) has agreed to undertake remedial actions at the DWI 1630 Site as specified under a Consent Order with the Tennessee Department of Environment and Conservation (TDEC) (Consent Order No. 90-3443, April 4, 1991), and as further delineated by a Memorandum of Understanding (MOU) between DOE and the State of Tennessee (MOU Regarding Implementation of Consent Orders, October 6, 1994). The soil and debris removal at the DWI 1630 Site is being performed by Bechtel Jacobs Company LLC (BJC) on behalf of the DOE. Remediation consists of removing contaminated soil and debris from the DWI 1630 site except for the landfill area and repairing the landfill cap. The DWI 1630 remediation waste that is being disposed at the Environmental Management Waste Management Facility (EMWMF) as defined as waste lot (WL) 146.1 and consists primarily of soils and soil like material, incidental debris and secondary waste generated from the excavation of debris and soil from the DWI 1630 site. The WL 146.1 includes soil, soil like material (e.g., shredded or chipped vegetation, ash), discrete debris items (e.g., equipment, drums, large scrap metal

  2. Challenges in the Biomedical Research Enterprise in the 21st century: Antecedents in the writings of David Triggle.

    PubMed

    Triggle, Christopher R; Williams, Michael

    2015-11-15

    David Triggle's career as an educator, researcher, essayist and ethicist in many ways has paralleled the post WWII emergence of the "biomedical research ecosystem" that originated in the concept of the "Endless Frontier". In the ensuing 70 years biomedical research has irreparably changed the nature of society with vaccines, the birth control pill and new generations of drugs and biologics to treat infections, sexually transmitted diseases, psychiatric disorders and cardiovascular diseases. These have led to a shift in the population demographic to the elderly and the chronically sick leading to major issues in the provision of effective and affordable healthcare for much of the world's population. In the present article, in addition to providing a brief biography and an appreciation of David Triggle's contributions to science, the authors expand on three topics in which he has had a major interest: improving the quality, reproducibility and relevance of basic biomedical research; declining career opportunities for graduates in an era of decreased funding-the end of the "Endless Frontier"; and the dynamic between the provision for universal healthcare and the dysfunctional, wasteful and politicized systems of the current medical-industrial complex in delivering healthcare.

  3. Professor David Poswillo CBE (1927-2003): Skilled oral and maxillofacial surgeon, influential scientist, teacher and adviser.

    PubMed

    Hawgood, Barbara J

    2014-02-01

    David Poswillo trained at Otago University Dental School, Dunedin, New Zealand (BDS) and the Royal College of Surgeons of England (FDSRCS). His great interest became the genesis and repair of cleft lip and palate and, in addition to clinical work, he undertook an experimental study of the embryology of cleft palate in pregnant rats exposed to three teratogenic agents. The microscopic work was carried out in his garden shed in Christchurch. His groundbreaking work on amniotic puncture at a critical period came to international notice and he was given the first Chair in Teratology of the Royal College of Surgeons. In experimental studies he showed that thalidomide induced focal haemorrhage in the developing embryo. Poswillo was also Consultant Oral Surgeon at Queen Victoria Hospital, East Grinstead and his skills as surgeon and teacher attracted numerous trainee surgeons. He was Professor of Oral Surgery in Adelaide and then in London. Poswillo was Chairman of two advisory committees whose lucid reports on anaesthesia, sedation and resuscitation in dentistry (Poswillo Report) and on tobacco and health were far-reaching and influential. David Poswillo had immense energy and enthusiasm and is remembered by many for his personal interest and stimulating guidance.

  4. Challenges in the Biomedical Research Enterprise in the 21st century: Antecedents in the writings of David Triggle.

    PubMed

    Triggle, Christopher R; Williams, Michael

    2015-11-15

    David Triggle's career as an educator, researcher, essayist and ethicist in many ways has paralleled the post WWII emergence of the "biomedical research ecosystem" that originated in the concept of the "Endless Frontier". In the ensuing 70 years biomedical research has irreparably changed the nature of society with vaccines, the birth control pill and new generations of drugs and biologics to treat infections, sexually transmitted diseases, psychiatric disorders and cardiovascular diseases. These have led to a shift in the population demographic to the elderly and the chronically sick leading to major issues in the provision of effective and affordable healthcare for much of the world's population. In the present article, in addition to providing a brief biography and an appreciation of David Triggle's contributions to science, the authors expand on three topics in which he has had a major interest: improving the quality, reproducibility and relevance of basic biomedical research; declining career opportunities for graduates in an era of decreased funding-the end of the "Endless Frontier"; and the dynamic between the provision for universal healthcare and the dysfunctional, wasteful and politicized systems of the current medical-industrial complex in delivering healthcare. PMID:26278976

  5. Professor David Poswillo CBE (1927-2003): Skilled oral and maxillofacial surgeon, influential scientist, teacher and adviser.

    PubMed

    Hawgood, Barbara J

    2014-02-01

    David Poswillo trained at Otago University Dental School, Dunedin, New Zealand (BDS) and the Royal College of Surgeons of England (FDSRCS). His great interest became the genesis and repair of cleft lip and palate and, in addition to clinical work, he undertook an experimental study of the embryology of cleft palate in pregnant rats exposed to three teratogenic agents. The microscopic work was carried out in his garden shed in Christchurch. His groundbreaking work on amniotic puncture at a critical period came to international notice and he was given the first Chair in Teratology of the Royal College of Surgeons. In experimental studies he showed that thalidomide induced focal haemorrhage in the developing embryo. Poswillo was also Consultant Oral Surgeon at Queen Victoria Hospital, East Grinstead and his skills as surgeon and teacher attracted numerous trainee surgeons. He was Professor of Oral Surgery in Adelaide and then in London. Poswillo was Chairman of two advisory committees whose lucid reports on anaesthesia, sedation and resuscitation in dentistry (Poswillo Report) and on tobacco and health were far-reaching and influential. David Poswillo had immense energy and enthusiasm and is remembered by many for his personal interest and stimulating guidance. PMID:24585846

  6. The moral status of the embryo: an attempt at an analysis with the aid of David Hume's ethics.

    PubMed

    Engel, J B; Hönig, A; Segerer, S; Häusler, S F M; Dietl, J; Djakovic, A

    2010-12-01

    This article applies the moral sentimentalism founded by David Hume to the moral status of the embryo. It will attempt to explain the paradoxical fact that in Germany abortion is common and socially accepted while preimplantation genetic diagnosis is banned with the aid of an approach based on moral sentimentalism. David Hume established the thesis that the human being is guided by the emotions and not by reason when making moral decisions. Scientific innovations often create a feeling of anxiety. Consequently, the initial moral judgment about it is negative. Due to this habit, the innovation is often accepted after a phase of indifference. This phenomenon has been observed in the case of heart transplantation, as well as for IVF. Consequently, the apparent contradiction in the varying degrees of the embryo's worthiness of protection in the womb and in the Petri dish is due to the simple fact that these are different stages of habituation. Therefore, the ethics of Hume cannot stipulate the embryo's moral status for once and for all; however, they can paradoxically raise the ongoing current debate to a more rational level through the insight that the underlying moral concepts are not based on reason alone.

  7. A Movie of the 1882 Transit of Venus Assembled from Plates Taken at Lick Observatory by David P. Todd

    NASA Astrophysics Data System (ADS)

    Misch, A.; Sheehan, W.

    2004-12-01

    We present a series of 141 photographic plates of the 1882 Transit of Venus, taken by David P. Todd at Lick Observatory. To our knowledge, the plates - which were recently rediscovered on Mount Hamilton - are by far the most complete photographic record of the transit. We also present the plates in the form of a high-resolution time-lapse movie, showing nearly all of the more than four hours of the transit visible from Mount Hamilton. The movie is notable for making visible an event that no living person has seen, but that has been lying dormant in the Lick archive for 120 years. The series also has a place of importance in the history of photography, and especially in the then-emerging art of chronophotography, the serial recording of a moving event.

  8. David Shakow and schizophrenia research at Worcester State Hospital: the roots of the scientist-practitioner model.

    PubMed

    Cautin, Robin L

    2008-01-01

    As Chief Psychologist and Director of Psychological Research at Worcester State Hospital (WSH), David Shakow (1901-1981) made substantial contributions to the scientific study of schizophrenia and by extension to the study of psychopathology in general. His methodological innovations--particularly on issues of diagnosis and conditions of testing-set a new standard for experimental rigor in the field. Shakow helped to establish many of what are considered basic facts about schizophrenia. His empirical work at WSH-specifically on the crossover effect--provided the scientific foundation for his theory of schizophrenic cognition, known as segmental set. Moreover, Shakow's schizophrenia work informed his developing ideas on the synergy between clinical practice and research.

  9. A philosophical analysis of David Orr's theory of ecological literacy: biophilia, ecojustice and moral education in school learning communities

    NASA Astrophysics Data System (ADS)

    Mitchell, Debra B.; Mueller, Michael P.

    2011-03-01

    In his writings, David Orr claims that the US is in an "ecological crisis" and that this stems from a crisis of education. He outlines a theory of ecological literacy, a mode by which we better learn the ecology of the Earth and live in a sustainable manner. While emphasizing a shock doctrine, the diagnosis of "crisis" may be correct, but it is short-lived for children and adults of the world. In this philosophical analysis of Orr's theory, it is argued that we move beyond the perspective of crisis. By extending Orr's ecological literacy with biophilia and ecojustice and by recognizing the importance of experience-in-learning, science education is envisioned to incorporate values and morals within a longer term ideology of educational reform.

  10. Health information technology is a vehicle, not a destination: a conversation with David J. Brailer. Interview by Arnold Milstein.

    PubMed

    Brailer, David J

    2007-01-01

    The first U.S. national health care information technology (IT) coordinator estimates that if the current rate of interoperable electronic health record (EHR) adoption is sustained through 2014, it would create a launchpad for quality gain and health care spending reduction in excess of 50 percent in the subsequent decade. But in this conversation with Leapfrog Group cofounder and U.S. health care purchasing innovator Arnold Milstein, David Brailer identifies several environmental changes as critical to the materialization of this dividend. These include providers' ceding control of clinical information to patients, universal public availability of provider performance comparisons, and moving health policy from a no-man's land between government and market control.

  11. The Integration of Jesus' Great Commandment within Christian Higher Education: An Analysis of the Leadership Praxis of Dr. David S. Dockery

    ERIC Educational Resources Information Center

    Hickman, Tanner Franklin

    2010-01-01

    The purpose of this study was to better understand the leadership philosophy and key strategic actions of Dr. David S. Dockery in relation to Jesus' Great Commandment. Dockery's leadership has been instrumental in shaping and defining the meaning of Christian education during his fourteen year tenure as president of Union University. During his…

  12. Dodecanuclear 3d/4f-metal clusters with a 'Star of David' topology: single-molecule magnetism and magnetocaloric properties.

    PubMed

    Alexandropoulos, Dimitris I; Cunha-Silva, Luís; Lorusso, Giulia; Evangelisti, Marco; Tang, Jinkui; Stamatatos, Theocharis C

    2016-01-28

    A family of interwoven molecular inorganic knots, shaped like the 'Star of David', was prepared by the employment of naphthalene-2,3-diol in 3d/4f-metal cluster chemistry; the isoskeletal dodecanuclear compounds exhibit slow relaxation of the magnetization and magnetocaloric properties, depending on the metal ion.

  13. How David P. Weikart's Highscope Summer Camp for (Gifted) Teenagers Became a Sustainable Model for My Later Work in Special Education and Inclusive Education

    ERIC Educational Resources Information Center

    Broecher, Joachim

    2015-01-01

    The HighScope Summer Camp for Teenagers founded by David P. Weikart in 1963, and operated until 2002, was an international, inclusive gifted education program that aided many young people, including those from disadvantaged social strata, in their personal development and shaped them in a special way. The six-week program stood for a high degree…

  14. "Maybe He's on the Toy Train": Empathising and Systemising in an Encounter with David Macaulay's "Black and White"

    ERIC Educational Resources Information Center

    Hardstaff, Sarah

    2014-01-01

    This study explores the responses of Abby, a young person with autism, to David Macaulay's 1990 picturebook "Black and White." Although both picturebook researchers and autism practitioners focus on the importance of encouraging empathetic responses to fictional characters, I build on Louise Collins' argument that…

  15. "Neither Can They Die Any More; for They Are Equal Unto the Angels": Secular Epiphanies in David Almond's "Counting Stars"

    ERIC Educational Resources Information Center

    Grace, Deborah

    2014-01-01

    Written before the successful publication of Skellig (1998), David Almond's short story collection, "Counting Stars," has attracted less critical attention than his more famous novels. Falling between fiction and autobiography, the earlier short stories are more firmly grounded in realism than the novels, which feature elements of…

  16. After Three Years: A Further Study of Libraries and Library Services in the State Institutions of Florida...Based on a Survey by David Kantor, 1967.

    ERIC Educational Resources Information Center

    Smith, Laura Snyder

    This survey is a revision of the 1967 survey made by David Kantor (ED 021 586) in view of the re-allocation of many services under the new Florida Constitution. The current status of the various institutions is noted throughout the survey. Besides the report on libraries, a description of the purposes and programs of each state institution grouped…

  17. Dodecanuclear 3d/4f-metal clusters with a 'Star of David' topology: single-molecule magnetism and magnetocaloric properties.

    PubMed

    Alexandropoulos, Dimitris I; Cunha-Silva, Luís; Lorusso, Giulia; Evangelisti, Marco; Tang, Jinkui; Stamatatos, Theocharis C

    2016-01-28

    A family of interwoven molecular inorganic knots, shaped like the 'Star of David', was prepared by the employment of naphthalene-2,3-diol in 3d/4f-metal cluster chemistry; the isoskeletal dodecanuclear compounds exhibit slow relaxation of the magnetization and magnetocaloric properties, depending on the metal ion. PMID:26666673

  18. "In the Hands of the Receivers": The Politics of Literacy in "The Savage" by David Almond and Dave McKean

    ERIC Educational Resources Information Center

    Hateley, Erica

    2012-01-01

    David Almond and Dave McKean's "The Savage" is a hybrid prose and graphic novel which tells the story of one young man's maturation through literacy. The protagonist learns to deal with the death of his father and his own "savage" self by writing a graphic novel. This article reads "The Savage" in the context of earlier, "Northern" literacy…

  19. Power Play: The Dynamics of Power and Interpersonal Communication in Higher Education as Reflected in David Mamet's "Oleanna"

    ERIC Educational Resources Information Center

    Chiaramonte, Peter

    2014-01-01

    David Mamet's play "Oleanna" may be infamous for reasons that do not do justice to the play's real accomplishments. One reason for the controversy is the author's apparent focus on sexual harassment. The play is not about sexual harassment. It is about power. And in particular the power of language to shape relationships…

  20. On "White Supremacy" and Caricaturing, Misrepresenting and Dismissing Marx and Marxism: A Response to David Gillborn's "Who's Afraid of Critical Race Theory in Education".

    ERIC Educational Resources Information Center

    Cole, Mike

    2009-01-01

    In this journal in 2007, the author and Alpesh Maisuria critiqued two central tenets of Critical Race Theory (CRT) from a Marxist perspective (Cole and Maisuria, 2007). These are its primacy of "race" over class, and its concept of "white supremacy". Part of the critique focused on the work of leading UK Critical Race Theorist, David Gillborn. A…

  1. The Marc Dax (1770-1837)/Paul Broca (1824-1880) controversy over priority in science: left hemisphere specificity for seat of articulate language and for lesions that cause aphemia.

    PubMed

    Buckingham, Hugh W

    2006-01-01

    One of the most fascinating and frustrating issues in the priority of discovery in science is over just who, for the first time, went on record in the public forum, either orally at a conference or through a published communication, proclaiming that the faculty of articulate human speech was located in the left, not the right, cortical hemisphere. The disputed paper was purportedly written in 1836 by Marc Dax, who died subsequently in 1837. He was a physician in southern France in the city of Montpellier--far from the medical center of Paris. Little note was made of the presumed paper until the early and mid-1860s, when the issue of language localization in the human brain took on increased activity, as the clinico-pathological method of explanation continued to flourish in the "Art of Physick." Marc Dax's son, Gustave, happened to be studying medicine in Paris in the 1860s, and, as most of the neuroscientific and anthropological researchers, came to know of Broca's published work, which in 1861, agreed with phrenological theory that this faculty was, indeed, in the anterior lobes, but further claimed, de novo, that the region in the anterior lobe was more precisely focused at the foot of the 3rd frontal convolution in that lobe, still assuming with phrenological theory and the "Law of Symmetry" that the faculty was bilaterally located. It was not until 1865 that Broca clearly, non-hesitatingly, and unambiguously claimed that the faculty was in the left hemisphere. As it turned out, Gustave, six weeks before Broca's paper appeared, had published the paper he said his father had written in 1836. In 1863, in fact, Gustave had submitted his (Gustave's) long monograph on aphemia, integrating what he claimed to be his father's 1836 pronouncement along with his own data. He sent this communication to the French Academy of Sciences and to the French Academy of Medicine; he heard nothing back from either academy. After waiting two years, he managed to publish his material

  2. New software for computer-assisted dental-data matching in Disaster Victim Identification and long-term missing persons investigations: "DAVID Web".

    PubMed

    Clement, J G; Winship, V; Ceddia, J; Al-Amad, S; Morales, A; Hill, A J

    2006-05-15

    In 1997 an internally supported but unfunded pilot project at the Victorian Institute of Forensic Medicine (VIFM) Australia led to the development of a computer system which closely mimicked Interpol paperwork for the storage, later retrieval and tentative matching of the many AM and PM dental records that are often needed for rapid Disaster Victim Identification. The program was called "DAVID" (Disaster And Victim IDentification). It combined the skills of the VIFM Information Technology systems manager (VW), an experienced odontologist (JGC) and an expert database designer (JC); all current authors on this paper. Students did much of the writing of software to prescription from Monash University. The student group involved won an Australian Information Industry Award in recognition of the contribution the new software could have made to the DVI process. Unfortunately, the potential of the software was never realized because paradoxically the federal nature of Australia frequently thwarts uniformity of systems across the entire country. As a consequence, the final development of DAVID never took place. Given the recent problems encountered post-tsunami by the odontologists who were obliged to use the Plass Data system (Plass Data Software, Holbaek, Denmark) and with the impending risks imposed upon Victoria by the decision to host the Commonwealth Games in Melbourne during March 2006, funding was sought and obtained from the state government to update counter disaster preparedness at the VIFM. Some of these funds have been made available to upgrade and complete the DAVID project. In the wake of discussions between leading expert odontologists from around the world held in Geneva during July 2003 at the invitation of the International Committee of the Red Cross significant alterations to the initial design parameters of DAVID were proposed. This was part of broader discussions directed towards developing instruments which could be used by the ICRC's "The Missing

  3. Characterization of three linalool synthase genes from Citrus unshiu Marc. and analysis of linalool-mediated resistance against Xanthomonas citri subsp. citri and Penicilium italicum in citrus leaves and fruits.

    PubMed

    Shimada, Takehiko; Endo, Tomoko; Fujii, Hiroshi; Rodríguez, Ana; Peña, Leandro; Omura, Mitsuo

    2014-12-01

    Three cDNA clones from Satsuma mandarin (Citrus unshiu Marc.) were isolated and expressed in Escherichia coli. CuSTS3-1 and CuSTS3-2 encode linalool synthases and CuSTS4 encodes a nerolidol/linalool synthase. Transcripts of CuSTS3-1, CuSTS3-2 and CuSTS4 were abundant in young fruit at 60 days after flowering (DAF), flowers and leaves, respectively. Treatments with Xanthomonas citri subsp. citri (XCC), the causal agent of citrus canker and Penicillium italicum (PI), the cause of post-harvest fruit decay, and wounding up-regulated CuSTS3-1 in fruit and mainly CuSTS4 in leaves. Linalool, citral, geraniol and citronellol showed strong antibacterial and antifungal activities against XCC and PI in vitro, while most other mono-and sesquiterpenes, including limonene and gamma-terpinene, did not. Linalool, used at levels similar to those present in resistant Ponkan mandarin (Citrus reticulata Blanco) leaves, was able to inhibit growth of XCC in vitro. Compared to other five citrus types, linalool accumulated at extraordinarily high levels in Ponkan mandarin leaves and was released at high amounts from their leaves, while it was hardly detectable in the most susceptible species, indicating that linalool biosynthesis and accumulation might be involved in plant defense against bacterial and fungal pathogens and be associated with field resistance to citrus canker.

  4. Characterization of three linalool synthase genes from Citrus unshiu Marc. and analysis of linalool-mediated resistance against Xanthomonas citri subsp. citri and Penicilium italicum in citrus leaves and fruits.

    PubMed

    Shimada, Takehiko; Endo, Tomoko; Fujii, Hiroshi; Rodríguez, Ana; Peña, Leandro; Omura, Mitsuo

    2014-12-01

    Three cDNA clones from Satsuma mandarin (Citrus unshiu Marc.) were isolated and expressed in Escherichia coli. CuSTS3-1 and CuSTS3-2 encode linalool synthases and CuSTS4 encodes a nerolidol/linalool synthase. Transcripts of CuSTS3-1, CuSTS3-2 and CuSTS4 were abundant in young fruit at 60 days after flowering (DAF), flowers and leaves, respectively. Treatments with Xanthomonas citri subsp. citri (XCC), the causal agent of citrus canker and Penicillium italicum (PI), the cause of post-harvest fruit decay, and wounding up-regulated CuSTS3-1 in fruit and mainly CuSTS4 in leaves. Linalool, citral, geraniol and citronellol showed strong antibacterial and antifungal activities against XCC and PI in vitro, while most other mono-and sesquiterpenes, including limonene and gamma-terpinene, did not. Linalool, used at levels similar to those present in resistant Ponkan mandarin (Citrus reticulata Blanco) leaves, was able to inhibit growth of XCC in vitro. Compared to other five citrus types, linalool accumulated at extraordinarily high levels in Ponkan mandarin leaves and was released at high amounts from their leaves, while it was hardly detectable in the most susceptible species, indicating that linalool biosynthesis and accumulation might be involved in plant defense against bacterial and fungal pathogens and be associated with field resistance to citrus canker. PMID:25443842

  5. David Kirkaldy (1820-1897) and his museum of destruction: the visual dilemmas of an engineer as man of science.

    PubMed

    Robertson, Frances

    2013-09-01

    This paper examines codes of representation in nineteenth century engineering in Britain in relation to broader visual culture. While engineering was promoted as a rational public enterprise through techniques of spectacular display, engineers who aimed to be taken seriously in the intellectual hierarchies of science had to negotiate suitable techniques for making and using images. These difficulties can be examined in the visual practices that mark the career of engineer David Kirkaldy. Beginning as a bravura naval draughtsman, Kirkaldy later negotiated his status as a serious experimenter in material testing science, changing his style of representation that at first sight seems to be in line with the 'objective' strategy in science of getting nature to represent herself. And although Kirkaldy maintained a range of visual styles to communicate with different audiences, making rhetorical use of several technologies of inscription, from hand drawing to photography, nevertheless, his work does in fact demonstrate new uses of the concept of objectivity in representation when up against the practices of engineering. While these might seem merely pragmatic in comparison to the ethical weight given to the discourse of objective representation in science, in the messy world of collapsing bridges and law suits, virtuous engineers had to develop various forms of visual knowledge as practical science. This was not 'applied science' but a differentiated form of enquiry whose complexities hold as much interest as the better known visual cultures of late nineteenth century science or art.

  6. Are we ready for sexual reorientation therapy in the U.S. military? A response to David W. Lutz.

    PubMed

    Hierholzer, Robert

    2004-01-01

    In his paper "The Catholic Church, the American Military, and Homosexual Reorientation Therapy," David W. Lutz ultimately concludes that it is "appropriate, and highly ethical" for the American military to offer reorientation therapy to help homosexuals overcome "the vice of sodomy." The major thrust of his paper, however, is to call for abandonment of the "Don't Ask/Don't Tell" policy currently in place in the military. Lutz's paper covers much ground, and this review begins by examining whether such a wide view is necessary for the ultimate conclusions. It goes on to ask whether Lutz has omitted to mention important considerations bearing on this issue, and whether Lutz's call for the introduction of reorientation therapy is a serious call or a symbolic response to homosexual activities. Lutz fails to address essential issues such as the actual experiences of other nations having homosexuals in the military, and issues regarding what constitutes "reorientation therapy," the latter leading to questions about how such a therapy would actually be implemented. PMID:15764097

  7. Post-transcriptional modifications and “Calmodulation” of voltage-gated calcium channel function: Reflections by two collaborators of David T Yue

    PubMed Central

    Soong, Tuck Wah; Mori, Masayuki X

    2016-01-01

    This review article is written to specially pay tribute to David T. Yue who was an outstanding human being and an excellent scientist who exuded passion and creativity. He exemplified an inter-disciplinary scientist who was able to cross scientific boundaries effortlessly in order to provide amazing understanding on how calcium channels work. This article provides a glimpse of some of the research the authors have the privilege to collaborate with David and it attempts to provide the thinking behind some of the research done. In a wider context, we highlight that calcium channel function could be exquisitely modulated by interaction with a tethered calmodulin. Post-transcriptional modifications such as alternative splicing and RNA editing further influence the Ca2+-CaM mediated processes such as calcium dependent inhibition and/or facilitation. Besides modifications of electrophysiological and pharmacological properties, protein interactions with the channels could also be influenced in a splice-variant dependent manner. PMID:26054929

  8. Revisiting the 1981 Nobel Prize to Roger Sperry, David Hubel, and Torsten Wiesel on the occasion of the centennial of the Prize to Golgi and Cajal.

    PubMed

    Berlucchi, Giovanni

    2006-12-01

    In 1981 the Nobel Prize for Medicine or Physiology was awarded to Roger Sperry for his work on the functional specialization of the cerebral hemispheres, and to David Hubel and Torsten Wiesel for their work on information processing in the visual system. The present paper points to some important links between the work of Sperry and that of Hubel and Wiesel and to their influences on neuroscience in the best tradition going back to Cajal. PMID:16997764

  9. David N. Reznick's The " Origin" Then and Now: An Interpretive Guide to the " Origin of Species": A Précis

    NASA Astrophysics Data System (ADS)

    Ruse, Michael

    2013-09-01

    David Reznick is one of the world's leading evolutionary biologists. His book on Charles Darwin's Origin of Species is given here in a précis, in order to show the underlying approach that he takes towards a work that is a classic in his field. It is shown that Reznick's interests are less in Darwin for his own sake and more in the importance of Darwin's ideas for science today.

  10. Revisiting the 1981 Nobel Prize to Roger Sperry, David Hubel, and Torsten Wiesel on the occasion of the centennial of the Prize to Golgi and Cajal.

    PubMed

    Berlucchi, Giovanni

    2006-12-01

    In 1981 the Nobel Prize for Medicine or Physiology was awarded to Roger Sperry for his work on the functional specialization of the cerebral hemispheres, and to David Hubel and Torsten Wiesel for their work on information processing in the visual system. The present paper points to some important links between the work of Sperry and that of Hubel and Wiesel and to their influences on neuroscience in the best tradition going back to Cajal.

  11. Digital Libraries and the Problem of Purpose [and] On DigiPaper and the Dissemination of Electronic Documents [and] DFAS: The Distributed Finding Aid Search System [and] Best Practices for Digital Archiving: An Information Life Cycle Approach [and] Mapping and Converting Essential Federal Geographic Data Committee (FGDC) Metadata into MARC21 and Dublin Core: Towards an Alternative to the FGDC Clearinghouse [and] Evaluating Website Modifications at the National Library of Medicine through Search Log analysis.

    ERIC Educational Resources Information Center

    Levy, David M.; Huttenlocher, Dan; Moll, Angela; Smith, MacKenzie; Hodge, Gail M.; Chandler, Adam; Foley, Dan; Hafez, Alaaeldin M.; Redalen, Aaron; Miller, Naomi

    2000-01-01

    Includes six articles focusing on the purpose of digital public libraries; encoding electronic documents through compression techniques; a distributed finding aid server; digital archiving practices in the framework of information life cycle management; converting metadata into MARC format and Dublin Core formats; and evaluating Web sites through…

  12. Implications of the sedimentology and isotope geochemistry of calcic horizons in the Pliocene-Early Pleistocene St. David Fm. , Arizona

    SciTech Connect

    Smith, G.A. . Dept. of Earth and Planetary Science); Wang, Y.; Cerling, T.E. )

    1992-01-01

    Two types of calcic horizons occur in pedogenically modified alluvial mudstones of the Plio-Pleistocene St. David Fm.: (1) nodular-carbonate zones (stage 2 morphology) with downward decreasing carbonate abundance, located below leached red muds; (2) massive to nodular zones (stage 3) with sharp bases, upward decrease in carbonate abundance, associated with variably leached muds typically exhibiting green mottles. Type 1 horizons are traceable for hundreds of meters; type 2 horizons vary in thickness and carbonate content over distances as short at 15 m. and are laterally contiguous with pond deposits. Type 1 horizons are interpreted as vadose aridosol calcic horizons, whereas type 2 horizons are partly gleyed hydromorphic soils with calcite derived from groundwater as well as from leaching within the soil. O and C isotopic compositions of age-equivalent 1 and 2 carbonates are similar suggesting that type 2 calcite formed in the unsaturated zone, probably in the capillary fringe above the water table. These latter horizons define a limited time of elevated water table, which corresponds to a cooler/wetter climate and higher sedimentation rates. If the distinction between these two soil types was not made, the greater morphological maturity'' of type 2 horizons would lead to misinterpretation of more arid climatic conditions or lower sedimentation rates. Type 1 horizons occur within parallel piedmont-facies belts representing channel/channel margin and floodplain deposition. Paleosols are morphologically similar, although floodplain soils are more clay rich. C-isotope analyses suggest, however, different vegetational histories for the two depositional tracts that reflect different responses of channel-margin and floodplain settings to increasing seasonality of precipitation during the late Pliocene.

  13. Is success a sin? A conversation with the reverend Peter J. Gomes. Interview by David A. Light.

    PubMed

    Gomes, P J

    2001-09-01

    The difficult task of achieving worldly success while also storing up spiritual treasure is perennially with us, in good times and in bad. Today, however, as the economy has cooled and companies have demonstrated their mortality, questions about meaning and value appear more relevant, even urgent. HBR associate editor David A. Light recently spoke with the Reverend Peter J. Gomes, one of the nation's best-known preachers and the minister at Harvard University's Memorial Church, about why and how it is both possible and necessary to reconcile a life of success with a life of faith. To do so, says Gomes, you must first "get used to it"--come to terms with the age-old tension between being rich in spirit and rich in worldly goods. Second, you should "get over it"--arrive at an understanding of the value and responsibilities associated with power and wealth. Finally, "get on with it"--figure out how you can live your life spiritually while continuing to lead in the business world. For those wondering how to get on with spiritual development, Gomes cites the growing phenomenon of senior executives gathering with peers--out of shared need, not shared accomplishment--to pray, study sacred texts, and share their religious life together. He counsels that it's never too late to get on with it: We can amend life at any time, whether we're 35, 45, or 75. Gomes concludes that business will continue to be one of the most significant forces in American culture, but it will always struggle against people's need for a perspective that is beyond this world's.

  14. Supplementation of a grape seed and grape marc meal extract decreases activities of the oxidative stress-responsive transcription factors NF-κB and Nrf2 in the duodenal mucosa of pigs

    PubMed Central

    2013-01-01

    Background In pigs, enteric infections and the development of gut disorders such as diarrhoea are commonly observed, particularly after weaning. The present study investigated the hypothesis that feeding a grape seed and grape marc extract (GSGME) as a dietary supplement has the potential to suppress the inflammatory process in the small intestine of pigs by modulating the activities of NF-κB and Nrf2 due to its high content of flavonoids. Methods Twenty-four crossbred, 6 weeks old pigs were randomly assigned to 2 groups of 12 animals each and fed nutritionally adequate diets without or with 1% GSGME for 4 weeks. Results Pigs administered GSGME had a lower transactivation of NF-κB and Nrf2 and a lower expression of various target genes of these transcription factors in the duodenal mucosa than control pigs (P < 0.05). Concentrations of α-tocopherol and thiobarbituric acid reactive substances (TBARS) in liver and plasma and total antioxidant capacity of plasma and relative mRNA abundances of NF-κB and Nrf2 target genes in the liver did not differ between the two groups. However, the ratio of villus height:crypt depth and the gain:feed ratio was higher in the pigs fed GSGME than in control pigs (P < 0.05). Conclusions This study shows that dietary supplementation of a polyphenol rich GSGME suppresses the activity of NF-κB in the duodenal mucosa of pigs and thus might provide a useful dietary strategy to inhibit inflammation in the gut frequently occurring in pigs. Feeding GSGME did not influence vitamin E status and the antioxidant system of the pigs but improved the gain:feed ratio. In overall, the study suggests that polyphenol-rich plant extracts such GSGME could be useful feed supplements in pig nutrition, in order to maintain animal health and improve performance. PMID:23453040

  15. The effect of grape seed and grape marc meal extract on milk performance and the expression of genes of endoplasmic reticulum stress and inflammation in the liver of dairy cows in early lactation.

    PubMed

    Gessner, D K; Koch, C; Romberg, F-J; Winkler, A; Dusel, G; Herzog, E; Most, E; Eder, K

    2015-12-01

    During the periparturient phase, cows are typically in an inflammation-like condition, and it has been suggested that inflammation associated with the development of stress of the endoplasmic reticulum (ER) in the liver contributes to the development of fatty liver syndrome and ketosis. In the present study, we investigated the hypothesis that feeding grape seed and grape marc meal extract (GSGME) as a plant extract rich in flavonoids attenuates inflammation and ER stress in the liver of dairy cows. Two groups of cows received either a total mixed ration as a control diet or the same total mixed ration supplemented with 1% of GSGME over the period from wk 3 prepartum to wk 9 postpartum. Dry matter intake during wk 3 to 9 postpartum was not different between the 2 groups. However, the cows fed the diet supplemented with GSGME had an increased milk yield and an increased daily milk protein yield. Cows supplemented with GSGME moreover had a significantly reduced mRNA abundancy of fibroblast growth factor (FGF) 21, a stress hormone induced by various stress conditions, in the liver in wk 1 and 3 postpartum. In contrast, mRNA abundances of a total of 3 genes involved in inflammation and 14 genes involved in ER stress response, as well as concentrations of triacylglycerols and cholesterol, in liver samples of wk 1 and 3 postpartum did not differ between the 2 groups. Overall, this study shows that supplementation of GSGME did not influence inflammation or ER stress in the liver but increased milk yield, an effect that could be due to effects on ruminal metabolism. PMID:26409958

  16. The effect of grape seed and grape marc meal extract on milk performance and the expression of genes of endoplasmic reticulum stress and inflammation in the liver of dairy cows in early lactation.

    PubMed

    Gessner, D K; Koch, C; Romberg, F-J; Winkler, A; Dusel, G; Herzog, E; Most, E; Eder, K

    2015-12-01

    During the periparturient phase, cows are typically in an inflammation-like condition, and it has been suggested that inflammation associated with the development of stress of the endoplasmic reticulum (ER) in the liver contributes to the development of fatty liver syndrome and ketosis. In the present study, we investigated the hypothesis that feeding grape seed and grape marc meal extract (GSGME) as a plant extract rich in flavonoids attenuates inflammation and ER stress in the liver of dairy cows. Two groups of cows received either a total mixed ration as a control diet or the same total mixed ration supplemented with 1% of GSGME over the period from wk 3 prepartum to wk 9 postpartum. Dry matter intake during wk 3 to 9 postpartum was not different between the 2 groups. However, the cows fed the diet supplemented with GSGME had an increased milk yield and an increased daily milk protein yield. Cows supplemented with GSGME moreover had a significantly reduced mRNA abundancy of fibroblast growth factor (FGF) 21, a stress hormone induced by various stress conditions, in the liver in wk 1 and 3 postpartum. In contrast, mRNA abundances of a total of 3 genes involved in inflammation and 14 genes involved in ER stress response, as well as concentrations of triacylglycerols and cholesterol, in liver samples of wk 1 and 3 postpartum did not differ between the 2 groups. Overall, this study shows that supplementation of GSGME did not influence inflammation or ER stress in the liver but increased milk yield, an effect that could be due to effects on ruminal metabolism.

  17. My New Friend, David.

    ERIC Educational Resources Information Center

    California State Univ., Los Angeles. National Dissemination and Assessment Center.

    This primary reader is intended for use in a bilingual education setting. It consists of a story about a little Hispanic boy's adventures in San Francisco's Chinatown. The story attempts to show children the value of knowing two languages and learning about different cultures. Each page has a large black-and-white illustration and presents the…

  18. The Garry David case.

    PubMed

    Parker, N

    1991-09-01

    A prisoner with an antisocial personality disorder had almost completed his sentence for attempted murder and there was considerable public concern over his imminent release. The article discusses the many attempts made by the Victorian Government during the past six months to detain him. A recommendation was made to change the Mental Health Act 1986 by including personality disorders as a form of "mental illness". The outcome of such advice has enormous implications for the practice of psychiatry in Victoria.

  19. NIEHS' David Rall

    ERIC Educational Resources Information Center

    Environmental Science and Technology, 1974

    1974-01-01

    According to Rall, director of NIEHS, the agency is supporting environmental research in the areas of occupational health, epidemiological, carcinogenic and biochemical toxicology, air pollution, food additives and nutrition. Rall's concern is that environmentalists have become sidetracked by the problems of esthetics and wildlife toxicity and…

  20. David Liberman's legacy.

    PubMed

    Arbiser, Samuel

    2014-08-01

    This article presents, in the author's own vision, his attempt to consider (and update) the work of an original thinker of contemporary psychoanalysis (in the present). Following a short overview of his biographical data and distinctive traits as maestro and man, it then tries to capture the implications and panoramic vision of Liberman's work, the prevailing questions and problems of psychoanalysis to which it responds. In the author's opinion this involves a serious attempt to systematize clinical psychoanalysis on the basis of singularity and of tolerance to human diversity, with the greatest precision and scientific rigour admitted by the psychoanalytic discipline - avoiding cliché on the one hand and what we might call the mystification of the Oracle on the other. The successive stages of Liberman's production are indicated in terms of the auxiliary disciplines (communication theory, semiotics and linguistics) which he used for his ever more precise systematization of clinical psychoanalysis finally leading to his proposals on 'style' and his vision of the psychopathology of over-adaptation and psychosomatic instances. Other concepts which this paper highlights are: Liberman's conception of analytic dialogue as framed by human interaction; his theorization which stems from this particular empirical base making use of 'operational definitions' and 'intermediary formulations'; his operational definition of transference; and the inclusion of setting inside the 'analytic situation'. PMID:25229544

  1. Lasser, David (1902-)

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    Science fiction editor and union organizer, born in Baltimore, MD, founded the American Interplanetary Society, the first organization in the USA to deal with space travel. Wrote an influential book, The Conquest of Space (1931). Derided in Congress as `not only a radical but a crackpot, with mental delusions we can travel to the Moon'....

  2. David Liberman's legacy.

    PubMed

    Arbiser, Samuel

    2014-08-01

    This article presents, in the author's own vision, his attempt to consider (and update) the work of an original thinker of contemporary psychoanalysis (in the present). Following a short overview of his biographical data and distinctive traits as maestro and man, it then tries to capture the implications and panoramic vision of Liberman's work, the prevailing questions and problems of psychoanalysis to which it responds. In the author's opinion this involves a serious attempt to systematize clinical psychoanalysis on the basis of singularity and of tolerance to human diversity, with the greatest precision and scientific rigour admitted by the psychoanalytic discipline - avoiding cliché on the one hand and what we might call the mystification of the Oracle on the other. The successive stages of Liberman's production are indicated in terms of the auxiliary disciplines (communication theory, semiotics and linguistics) which he used for his ever more precise systematization of clinical psychoanalysis finally leading to his proposals on 'style' and his vision of the psychopathology of over-adaptation and psychosomatic instances. Other concepts which this paper highlights are: Liberman's conception of analytic dialogue as framed by human interaction; his theorization which stems from this particular empirical base making use of 'operational definitions' and 'intermediary formulations'; his operational definition of transference; and the inclusion of setting inside the 'analytic situation'.

  3. A Novel HURRAH Protocol Reveals High Numbers of Monomorphic MHC Class II Loci and Two Asymmetric Multi-Locus Haplotypes in the Père David's Deer

    PubMed Central

    Wan, Qiu-Hong; Zhang, Pei; Ni, Xiao-Wei; Wu, Hai-Long; Chen, Yi-Yan; Kuang, Ye-Ye; Ge, Yun-Fa; Fang, Sheng-Guo

    2011-01-01

    The Père David's deer is a highly inbred, but recovered, species, making it interesting to consider their adaptive molecular evolution from an immunological perspective. Prior to this study, genomic sequencing was the only method for isolating all functional MHC genes within a certain species. Here, we report a novel protocol for isolating MHC class II loci from a species, and its use to investigate the adaptive evolution of this endangered deer at the level of multi-locus haplotypes. This protocol was designated “HURRAH” based on its various steps and used to estimate the total number of MHC class II loci. We confirmed the validity of this novel protocol in the giant panda and then used it to examine the Père David's deer. Our results revealed that the Père David's deer possesses nine MHC class II loci and therefore has more functional MHC class II loci than the eight genome-sequenced mammals for which full MHC data are currently available. This could potentially account at least in part for the strong survival ability of this species in the face of severe bottlenecking. The results from the HURRAH protocol also revealed that: (1) All of the identified MHC class II loci were monomorphic at their antigen-binding regions, although DRA was dimorphic at its cytoplasmic tail; and (2) these genes constituted two asymmetric functional MHC class II multi-locus haplotypes: DRA1*01 ∼ DRB1 ∼ DRB3 ∼ DQA1 ∼ DQB2 (H1) and DRA1*02 ∼ DRB2 ∼ DRB4 ∼ DQA2 ∼ DQB1 (H2). The latter finding indicates that the current members of the deer species have lost the powerful ancestral MHC class II haplotypes of nine or more loci, and have instead fixed two relatively weak haplotypes containing five genes. As a result, the Père David's deer are currently at risk for increased susceptibility to infectious pathogens. PMID:21267075

  4. RAS Awards and Prizes: RAS Awards 2009; Gold Medal: Prof. David Williams; Gold Medal: Prof. Eric Priest; Price Medal: Prof. Malcolm Sambridge; Eddington Medal: Prof. James Pringle

    NASA Astrophysics Data System (ADS)

    2009-02-01

    Each year the RAS recognizes outstanding achievement in astronomy and geophysics by the award of medals and prizes. Candidates are nominated by Fellows and the awards made by a committee of Fellows, ensuring that these scientists have earned the respect and admiration of their peers in the research community. The Gold Medal for Astronomy is awarded to Prof. David Williams of University College London. The Gold Medal for Geophysics is awarded to Prof. Eric Priest of the University of St Andrews. The Price Medal is awarded to Prof. Malcolm Sambridge of the Australian National University. The Eddington Medal is given to Prof. James Pringle of the University of Cambridge.

  5. Stephen Marc: Photographer for Our Time

    ERIC Educational Resources Information Center

    Smith, Toni M. Shorter

    2012-01-01

    It is said that "a picture is worth a thousand words" as visual images can express complex and multilayered ideas. Sometimes photographic imagery is so strong and resonant of certain success, struggles, or events that it becomes key to a community or generation. As historic records, photographs are uniquely able to present not only success and…

  6. Redescriptions and lectotype designations of Central American species of Phaenonotum Sharp (Coleoptera, Hydrophilidae) based on the type material from the David Sharp collection

    PubMed Central

    Deler-Hernández, Albert; Fikáček, Martin

    2016-01-01

    Abstract In order to understand the identity of the Central American species of the genus Phaenonotum Sharp, 1882, the type specimens of the species described by Sharp (1882) deposited in the David Sharp collection in the Natural History Museum in London have been re-examined. The following species are redescribed: Phaenonotum apicale Sharp, 1882, Phaenonotum collare Sharp, 1882, Phaenonotum dubium Sharp, 1882 (confirmed as junior synonym of Phaenonotum exstriatum (Say, 1835)), Phaenonotum laevicolle Sharp, 1882, Phaenonotum rotundulum Sharp, 1882 and Phaenonotum tarsale Sharp, 1882. Lectotypes are designated for Phaenonotum apicale, Phaenonotum collare, Phaenonotum rotundulum and Phaenonotum tarsale. External diagnostic characters and morphology of male genitalia are illustrated. A table summarizing diagnostic characters allowing the identification of the species is provided. PMID:27110202

  7. Redescriptions and lectotype designations of Central American species of Phaenonotum Sharp (Coleoptera, Hydrophilidae) based on the type material from the David Sharp collection.

    PubMed

    Deler-Hernández, Albert; Fikáček, Martin

    2016-01-01

    In order to understand the identity of the Central American species of the genus Phaenonotum Sharp, 1882, the type specimens of the species described by Sharp (1882) deposited in the David Sharp collection in the Natural History Museum in London have been re-examined. The following species are redescribed: Phaenonotum apicale Sharp, 1882, Phaenonotum collare Sharp, 1882, Phaenonotum dubium Sharp, 1882 (confirmed as junior synonym of Phaenonotum exstriatum (Say, 1835)), Phaenonotum laevicolle Sharp, 1882, Phaenonotum rotundulum Sharp, 1882 and Phaenonotum tarsale Sharp, 1882. Lectotypes are designated for Phaenonotum apicale, Phaenonotum collare, Phaenonotum rotundulum and Phaenonotum tarsale. External diagnostic characters and morphology of male genitalia are illustrated. A table summarizing diagnostic characters allowing the identification of the species is provided.

  8. Is There Still Time to Avoid `Dangerous Anthropogenic Interference' with Global Climate? The Importance of the Work of Charles David Keeling

    NASA Astrophysics Data System (ADS)

    Hansen, J.

    2005-12-01

    David Keeling altered our perspectives about global change with his painstaking observations of atmospheric carbon dioxide. The now famous `Keeling curve', measuring both the pulse of Nature and a steadily rising human impact on atmospheric composition, has invariably been hailed as our most rigorous and fundamental measure of global change. Carbon dioxide has been joined by other key metrics that help define the causes and consequences of global climate change. The Earth's history provides our best indication of the levels of change that are likely to have deleterious effects on humans and wildlife. This discussion of climate metrics will present up-to-date measures of the agents of global change and climate change itself, including steps to minimize and assess measurement biases. The metrics are beginning to paint an increasingly clear picture of humanity's prospects for avoiding `dangerous anthropogenic interference' with global climate.

  9. ‘The Solution to his Own Enigma’: Connecting the Life of Montague David Eder (1865–1936), Socialist, Psychoanalyst, Zionist and Modern Saint1

    PubMed Central

    THOMSON, MATHEW

    2011-01-01

    This article examines the career of pioneer British psychoanalyst David Eder (1865–1936). Credited by Freud as the first practising psychoanalyst in England, active in early British socialism and then a significant figure in Zionism in post-war Palestine, and in between an adventurer in South America, a pioneer in the field of school medicine, and a writer on shell-shock, Eder is a strangely neglected figure in existing historiography. The connections between his interest in medicine, psychoanalysis, socialism and Zionism are also explored. In doing so, this article contributes to our developing understanding of the psychoanalytic culture of early twentieth-century Britain, pointing to its shifting relationship to broader ideology and the practical social and political challenges of the period. The article also reflects on the challenges for both Eder’s contemporaries and his biographers in making sense of such a life. PMID:23752865

  10. The Liberating Role of Astronomy in an Old Farmer's Almanac: David Rittenhouse's "Useful Knowledge" and a Benjamin Banneker Almanac for 1792

    NASA Astrophysics Data System (ADS)

    Walker, Theodore, Jr.

    2012-06-01

    Traditionally, astronomy met theology and political ethics in almanacs. As presented in early New England almanacs of the farmer's type, astronomy was deity-affirming and liberty-oriented. The old English label for astronomy that affirms theology was "Astro-theology" (William Derham, 1715). The New England rendering of astro-theology was so strongly oriented towards liberty that it can now be labeled astro-liberation theology. This 21st century label is appropriate because 18th century New England printers and astronomers used astronomy to demonstrate the glory of the Creator (astro-theology) and to encourage liberation from colonialism and slavery (astro-liberation theology). A philosophy of astronomy as "useful knowledge' expressed by David Rittenhouse in 1775 - and implicit in a Benjamin Banneker almanac for 1792 - included liberty-oriented visions of planet Earth as seen from outer space, and liberty-oriented visions of intelligent life on other planets orbiting other stars.

  11. Clinical trials update from Heart Rhythm 2007 and Heart Failure 2007: CARISMA, PREPARE, DAVID II, SAVE-PACE, PROTECT and AREA-IN-CHF.

    PubMed

    Cleland, John G F; Coletta, Alison P; Abdellah, Ahmed Tageldien; Witte, Klaus K; Hobson, Neil; Clark, Andrew L

    2007-08-01

    This article provides information and a commentary on trials relevant to the pathophysiology, prevention and treatment of heart failure, presented at Heart Rhythm 2007 organised by the Heart Rhythm Society which was held in Denver, USA and Heart Failure 2007 organised by the Heart Failure Association of the European Society of Cardiology which was held in Hamburg, Germany. Unpublished reports should be considered as preliminary data, as analyses may change in the final publication. The CARISMA study suggests that non-invasive screening tests may help to identify post-MI patients who may benefit from ICD therapy. Data from the PREPARE study show that more conservative ICD programming can reduce morbidity at the cost of an increased risk of arrhythmic syncope. DAVID II indicates that atrial pacing may be a safe alternative to ventricular back-up pacing in patients with left ventricular dysfunction and standard indications for an ICD. The incidence of persistent atrial fibrillation in patients with sinus node disease in SAVE-PACE was reduced by dual chamber minimal ventricular pacing compared to conventional dual chamber pacing. The pilot phase of the PROTECT studies confirmed 30 mg as the dose of the selective A1 adenosine receptor antagonist KW-3902 to be used in pivotal studies. AREA-IN-CHF failed to show a beneficial effect of canrenone on LV volumes compared to placebo however some beneficial effects on secondary clinical endpoints were observed.

  12. Development of a headspace-solid phase micro extraction method to monitor changes in volatile profile of rose (Rosa hybrida, cv David Austin) petals during processing.

    PubMed

    Bianchi, Giulia; Nuzzi, Monica; Avitabile Leva, Alexa; Rizzolo, Anna

    2007-05-25

    In the present study, headspace solid phase microextraction combined to capillary gas chromatography (HS-SPME-GC) has been applied for the determination of changes in the volatile profile of rose petals (Rosa hybrida, cvs David Austin) following processing (heat treatment and addition as an ingredient to a food product--for example yoghurt). Four SPME fibres at two sampling temperatures (40 and 60 degrees C) with a sampling time of 30 min were examined. Volatile profiles were detected either by FID or/and by olfactometry (ODP-II, Gerstel). Fibre testing was performed using raw rose petals for sampling temperature selection and an 18 characteristic rose volatile standard mixture in water was used to compare fibre performances at the sampling temperature of 60 degrees C. Polydimethylsiloxane-divinylbenzene (PDMS-DVB) fibre at the sampling temperature of 60 degrees C was the most suitable to sample the rose alcohols phenyl ethanol, citronellol, nerol, geraniol and eugenol, as assessed by GC-olfactometry, not only from raw petals, but also from processed rose petals and the food product. PDMS-DVB fibre also showed a desired low affinity to volatiles from yoghurt, which reduces the influence of food matrix on the volatile profile. The method was linear over two orders of magnitude and had satisfactory repeatability, with limits of detection for the rose alcohols ranging from <1 to 10 ng/ml concentration levels.

  13. Clinical trials update from Heart Rhythm 2007 and Heart Failure 2007: CARISMA, PREPARE, DAVID II, SAVE-PACE, PROTECT and AREA-IN-CHF.

    PubMed

    Cleland, John G F; Coletta, Alison P; Abdellah, Ahmed Tageldien; Witte, Klaus K; Hobson, Neil; Clark, Andrew L

    2007-08-01

    This article provides information and a commentary on trials relevant to the pathophysiology, prevention and treatment of heart failure, presented at Heart Rhythm 2007 organised by the Heart Rhythm Society which was held in Denver, USA and Heart Failure 2007 organised by the Heart Failure Association of the European Society of Cardiology which was held in Hamburg, Germany. Unpublished reports should be considered as preliminary data, as analyses may change in the final publication. The CARISMA study suggests that non-invasive screening tests may help to identify post-MI patients who may benefit from ICD therapy. Data from the PREPARE study show that more conservative ICD programming can reduce morbidity at the cost of an increased risk of arrhythmic syncope. DAVID II indicates that atrial pacing may be a safe alternative to ventricular back-up pacing in patients with left ventricular dysfunction and standard indications for an ICD. The incidence of persistent atrial fibrillation in patients with sinus node disease in SAVE-PACE was reduced by dual chamber minimal ventricular pacing compared to conventional dual chamber pacing. The pilot phase of the PROTECT studies confirmed 30 mg as the dose of the selective A1 adenosine receptor antagonist KW-3902 to be used in pivotal studies. AREA-IN-CHF failed to show a beneficial effect of canrenone on LV volumes compared to placebo however some beneficial effects on secondary clinical endpoints were observed. PMID:17644412

  14. Investigation of Neospora caninum seroprevalence and potential impact on reproductive success in semi-free-ranging Père David's deer (Elaphurus davidianus)

    PubMed Central

    Bapodra, Priya; Wolfe, Barbara A

    2015-01-01

    This study aimed to determine the prevalence and reproductive impact of Neospora caninum in a herd of semi-free-ranging Père David's deer (Elaphurus davidianus) at a conservation facility, following a suspected abortion storm in 2008. Serum samples (n=103) collected from 60 individuals between 2002 and 2011 were evaluated using competitive ELISA for the detection of N. caninum-specific antibodies. Of the 103 samples, 73 (70.9 per cent) were positive for N. caninum antibodies, with a mean±sd competitive inhibition (CI) of 77.6±19.8 per cent. Thirty (29.1 per cent) samples were seronegative, with mean CI of 15.2±9.70 per cent. A significant negative linear relationship was noted between the proportion of seropositive animals and age (R2=0.228, P<0.001). Calving rates of adult females from 2005 to 2011 ranged from 15.4 per cent to 52 per cent (mean 35.5±11.3 per cent), and did not correlate with mean CI values (Spearman's rank correlation coefficient=0.072, P=0.878). While both horizontal and transplacental transmission are likely contributing to persistent herd seropositivity, the role of N. caninum in reproductive success in this and other populations of endangered ungulates remains to be explored. PMID:26392906

  15. In response to David Greenwood's `Place mobility and faculty life: mindfulness through change' through the lens of science teacher education programs

    NASA Astrophysics Data System (ADS)

    Nyaema, Mary K.

    2016-08-01

    In writing this review, I draw on the experience of David Greenwood (Cult Stud Sci Educ 10:5-16, 2015) whose ethnographic study sheds light on his growth as a faculty member who has taught in various settings that are quite different from the culture that he grew up with. I extend his thoughts on ecological mindfulness to encompass a culturally aware method of teaching based on place sensitized more to the needs of science teacher preparation programs. The methods used in writing the review included literature searches for articles that incorporate ecological mindfulness and culturally responsive teaching in science teacher preparation programs and reflected ideas voiced in Greenwood's article. Although he seems that he is primarily addressing other faculty members, his experiences can be used as lifelong lessons for preservice teachers entering a primarily homogeneous workforce expected to teach an increasingly diverse student population. His humor, use of Haiku, poetry and mindfulness as a way of becoming one with a culture that he is not accustomed has many lessons that prove useful in training more culturally responsive teachers. In light of an increasingly diverse US student population versus a stagnantly homogeneous teaching workforce, his reflective practice will prove useful to teachers who are expected to teach students with cultures different from their own.

  16. From precocious fame to mature obscurity: David Walker (1837-1917) MD, LRCSI, surgeon and naturalist to the Fox Arctic Expedition of 1857-59.

    PubMed

    Froggatt, Peter; Walker, Brian M

    2012-11-01

    The Belfast-born David Walker was the 19-year-old surgeon and naturalist on the epic Fox Arctic Expedition (1857-59) that established the fate of Sir John Franklin's unsuccessful (1845) search for the North-West Passage. On return the crew were fêted as heroes and decorated, and shared in a £5000 government bounty: Walker was also received by the Queen and (in Ireland) by the Lord Lieutenant, was honoured by the principal British and Irish natural history societies and his portrait was exhibited in the National Portrait Gallery, London. This paper describes his adventurous life, including the Fox Expedition, which from 1862 was spent abroad and included time in the Cariboo gold fields, service in the United States Army, practice in a notorious Californian frontier town and, in later life, the comparative quiet of general and occupational medical practice in Portland, Oregon. Once a household name, his death went unrecorded in the British and Irish medical and lay press.

  17. Development testing of the chemical analysis automation polychlorinated biphenyl standard analysis method during surface soils sampling at the David Witherspoon 1630 site

    SciTech Connect

    Hunt, M.A.; Klatt, L.N.; Thompson, D.H.

    1998-02-01

    The Chemical Analysis Automation (CAA) project is developing standardized, software-driven, site-deployable robotic laboratory systems with the objective of lowering the per-sample analysis cost, decreasing sample turnaround time, and minimizing human exposure to hazardous and radioactive materials associated with DOE remediation projects. The first integrated system developed by the CAA project is designed to determine polychlorinated biphenyls (PCB) content in soil matrices. A demonstration and development testing of this system was conducted in conjuction with surface soil characterization activities at the David Witherspoon 1630 Site in Knoxville, Tennessee. The PCB system consists of five hardware standard laboratory modules (SLMs), one software SLM, the task sequence controller (TSC), and the human-computer interface (HCI). Four of the hardware SLMs included a four-channel Soxhlet extractor, a high-volume concentrator, a column cleanup, and a gas chromatograph. These SLMs performed the sample preparation and measurement steps within the total analysis protocol. The fifth hardware module was a robot that transports samples between the SLMs and the required consumable supplies to the SLMs. The software SLM is an automated data interpretation module that receives raw data from the gas chromatograph SLM and analyzes the data to yield the analyte information. The TSC is a software system that provides the scheduling, management of system resources, and the coordination of all SLM activities. The HCI is a graphical user interface that presents the automated laboratory to the analyst in terms of the analytical procedures and methods. Human control of the automated laboratory is accomplished via the HCI. Sample information required for processing by the automated laboratory is entered through the HCI. Information related to the sample and the system status is presented to the analyst via graphical icons.

  18. Once a physicist: David Florence

    NASA Astrophysics Data System (ADS)

    Florence, David

    2009-03-01

    I did mathematical physics because it was just what I was best at. I enjoyed it at school, so I applied to do it at Nottingham University. I fell into it, to be quite honest. Once at university, I struggled at first, partly because I found it quite difficult to combine studying with competing and training in sport, which is pretty much full time as well. But by the end of my university career, I had learned to be organized, and to manage my time pretty effectively, so I enjoyed it a lot more.

  19. David Georgi's Cal Council Presidency

    ERIC Educational Resources Information Center

    Georgi, David

    2015-01-01

    When the author was asked to write a mini-memoir about his time as Cal Council president, his first thought was "Now, when exactly was that?" He says that pretty much summarizes the quality of his memory these days. The author's first contact with the California Council on the Education of Teachers was back in the 1970s when the…

  20. Once a physicist: David Roy

    NASA Astrophysics Data System (ADS)

    2010-02-01

    My interest in science started very early, probably with science-fiction books like the Tom Swift series, which are aimed at children. After brief stints in chemistry and engineering, I chose to study physics at Boston University because I found it the most challenging. I also had dreams of being an "inventor" and thought physics would give me an understanding of how things worked.

  1. The vision of David Marr.

    PubMed

    Stevens, Kent A

    2012-01-01

    Marr proposed a computational paradigm for studying the visual system, wherein aspects of vision would be amenable to study with what might be regarded a computational-reductionist approach. First, vision would be cleaved into separable 'computational theories', in which the visual system is characterized in terms of its computational goals and the strategies by which they are carried out. Each such computational theory could then be investigated in increasingly concrete terms, from symbols and measurements, to representations and algorithms, to processes and neural implementations. This paradigm rests on some general expectations of a symbolic information processing system, including his stated principles of explicit naming, modular design, least commitment, and graceful degradation. In retrospect, the computational framework also tacitly rests on additional assumptions about the nature of biological information processing: (1) separability of computational strategies, (2) separability of representations, (3) a pipeline nature of information processing, and that (4) the representations employ primitives of low dimensionality. These assumptions are discussed in this retrospective.

  2. Vergano Receives David Perlman Award

    NASA Astrophysics Data System (ADS)

    Kelly, Sue

    2006-08-01

    Dan Vergano received the Perlman Award at the Joint Assembly Honors Ceremony, whichwas held on 25 May 2006 in Baltimore, Md. Vergano was honored for `The Debate's over:Globe is warming,' which describes the linkages between the science of climate change andthe complexity of technical and economic decisions facing its mitigation.

  3. National Aspects of Creating and Using MARC/RECON Records.

    ERIC Educational Resources Information Center

    Rather, John C., Ed.; Avram, Henriette D., Ed.

    The Retrospective Conversion (RECON) Working Task Force investigated the problems of converting retrospective catalog records to machine readable form. The major conclusions and recommendations of the Task Force cover five areas: the level of machine-readable records, conversion of other machine-readable data bases, a machine-readable National…

  4. Robots Save Soldiers' Lives Overseas (MarcBot)

    NASA Technical Reports Server (NTRS)

    2009-01-01

    Marshall Space Flight Center mobile communications platform designs for future lunar missions led to improvements to fleets of tactical robots now being deployed by U.S. Army. The Multi-function Agile Remote Control Robot (MARCbot) helps soldiers search out and identify improvised explosive devices. NASA used the MARCbots to test its mobile communications platform, and in working with it, made the robot faster while adding capabilities -- upgrading to a digital camera, encrypting the controllers and video transmission, as well as increasing the range and adding communications abilities. They also simplified the design, providing more plug-and-play sensors and replacing some of the complex electronics with more trouble-free, low-cost components. Applied Geo Technology, a tribally-owned corporation in Choctaw, Mississippi, was given the task of manufacturing the modified robots. The company is now producing 40 units per month, 300 of which have already been deployed overseas.

  5. MARC and the Library Service Center: Automation at Bargain Rates.

    ERIC Educational Resources Information Center

    Pearson, Karl M.

    Despite recent research and development in the field of library automation, libraries have been unable to reap the benefits promised by technology due to the high cost of building and maintaining their own computer-based systems. Time-sharing and disc mass storage devices will bring automation costs, if spread over a number of users, within the…

  6. Project Explorer GAS #007: Marshall Amateur Radio Club Experiment (MARCE)

    NASA Technical Reports Server (NTRS)

    Stluka, E. F.

    1986-01-01

    Polls were taken at the Project Explorer meetings regarding flying without the radio experiment transmitting. The radio downlinks require extra coordination and are sensitive to certain payloads. The poll results were unanimous. The radio downlinks are vital in providing data on the health and status of the total experiments package, in real time, during the flight. The amateur radio operators, prepared to receive the downlinks and OSCAR-10 relays, revealed that there was enormous interest throughout the world, to participate. This sets the stage for the reflight opportunities which the GAS program has provided. Major activities, pertinent to the STS-41G flight preparations by the GAS #007 team and support group, are listed.

  7. File Size and the Cost of Processing MARC Records

    ERIC Educational Resources Information Center

    Kennedy, John P.

    1971-01-01

    The ratio of titles selected to titles read from the cumulative file is the most significant determinant of cost and an effective formula for limiting the growth of the file must be developed for an economical system. (AB)

  8. Two Students Win AGU Scholarships

    NASA Astrophysics Data System (ADS)

    Howard, Claire

    2013-11-01

    AGU is pleased to announce the winners of two scholarships. Marc Neveu is the recipient of the 2013 David S. Miller Young Scientist Scholarship, which recognizes a student of the Earth sciences whose academic work exhibits interest and promise. Hima Hassenruck-Gudipati is the 2013 recipient of the David E. Lumley Scholarship, which recognizes a high-achieving student who is working on problems of global importance in the energy and environmental sectors of industry and academia.

  9. Extending David Horrobin's membrane phospholipid theory of schizophrenia: overactivity of cytosolic phospholipase A(2) in the brain is caused by overdrive of coupled serotonergic 5HT(2A/2C) receptors in response to stress.

    PubMed

    Eggers, Arnold E

    2012-12-01

    David Horrobin's membrane phospholipid theory of schizophrenia has held up well over time because his therapeutic prediction that dietary supplementation with eicosapentaenoic acid (EPA) would have a therapeutic effect has been partially verified and undergoes continued testing. In the final version of his theory, he hypothesized that there was hyperactivity of phosphoslipase A(2) (PLA(2)) or a related enzyme but did not explain how the hyperactivity came about. It is known that serotonergic 5HT(2A/2C) receptors are coupled to PLA(2), which hydrolyzes both arachidonic acid (AA) and EPA from diacylglycerides at the sn-2 position. In this paper, Horrobin's theory is combined with a previously published theory of chronic stress in which it was hypothesized that a disinhibited dorsal raphe nucleus, the principal nucleus of the serotonergic system, can organize the neuropathology of diseases such as migraine, hypertension, and the metabolic syndrome. The new or combined theory is that schizophrenia is a disease of chronic stress in which a disinhibited DRN causes widespread serotonergic overdrive in the cerebral cortex. This in turn causes overdrive of cPLA(2) and both central and peripheral depletion of AA and EPA. Because EPA is present in smaller amounts, it falls below threshold for maintaining an intracellular balance between AA-derived and EPA-derived second messenger cascades, which leads to abnormal patterns of neuronal firing. There are two causes of neuronal dysfunction: the disinhibited DRN and EPA depletion. Schizophrenia is statistically associated with metabolic syndrome, hypertension, and migraine because they form a cluster of diseases with similar pathophysiology. The theory provides an explanation for both the central and peripheral phospholipid abnormalities in schizophrenia. It also explains the role of stress in schizophrenia, elevated serum PLA(2) activity in schizophrenia, the relationship between untreated schizophrenia and metabolic syndrome

  10. Are Adolescents Talking with Their Parents about Sex before Becoming Sexually Active? Fact Sheet

    ERIC Educational Resources Information Center

    Leuschner, Kristin

    2010-01-01

    This paper examines parent-child discussions of sexual behavior. It finds consistency in the timing and content of such discussions; however, many parents and children do not discuss key topics, such as birth control, before adolescents become sexually active. [This fact sheet is based on Megan K. Beckett, Marc N. Elliott, Steven Martino, David E.…

  11. A resolution commending David J. Schiappa.

    THOMAS, 113th Congress

    Sen. McConnell, Mitch [R-KY

    2013-08-01

    08/01/2013 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S6142-6143; text as passed Senate: CR S6142; text of measure as introduced: CR S6142) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  12. Building Big with David Macaulay. Activity Guide.

    ERIC Educational Resources Information Center

    Sammons, James; Sammons, Fran Lyons; Curtis, Paul

    This activity guide is designed for educators and features suggestions for possible activity paths for different amounts of available time and survival tips for activity leaders. Each activity is divided into two sections--educator ideas and activity handouts. Activity sections include: (1) Foundations; (2) Bridges; (3) Domes; (4) Skyscrapers; (5)…

  13. 78 FR 26784 - David Freeman: Debarment Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-08

    ... each package. The pills were in blister packs on which was written ``Omega Biotech LTD.'' Mr. Freeman... relevant times, neither Muhi Trading Corporation nor Omega Biotech LTD. were registered to manufacture... the Division of Dockets Management between 9 a.m. and 4 p.m., Monday through Friday. Dated: April...

  14. David Levy's Guide to Observing Meteor Showers

    NASA Astrophysics Data System (ADS)

    Levy, David H.

    2007-11-01

    Preface; 1. July 4, 1956; 2. What is a meteor?; 3. Some historical notes; 4. Small rocks and dust in space; 5. Observing meteors; 6. Recording meteors; 7. Quadrantids; 8. Lyrids; 9. The Eta Aquarids; 10. The Omicron Draconids; 11. Delta Aquarids; 12. Perseids; 13. The Gamma Pavonids; 14. Orionids; 15. Taurids; 16. Leonids; 17. Geminids; 18. Ursids; 19. Meteor showers throughout the year; Appendix.

  15. Quantum Linguistics: A Response to David Mallows.

    ERIC Educational Resources Information Center

    Hill, Kent A.

    2003-01-01

    Responds to an earlier article that illustrated how metaphorically applying chaos and complexity theory to language teaching, second language acquisition, and the observed lesson can alter perspectives about how these things are viewed. Suggests that chaos and complexity theory could also help see the following areas in a new light: syllabus…

  16. David V. Tiedeman: Engineer of Career Construction

    ERIC Educational Resources Information Center

    Savickas, Mark L.

    2008-01-01

    Tiedeman (1919-2004) designed the blueprint for equipping and building career construction theory. After making significant contributions to the statistical analysis of occupational behavior, he shifted to a constructivist epistemology for comprehending careers as the imposition of direction on vocational behavior. The cornerstones of his…

  17. Gill, Sir David (1843-1914)

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    Astronomer, born in Aberdeen, trained as a watchmaker, had a private observatory near Aberdeen, became Her Majesty's Astronomer at the Cape of Good Hope. He redetermined the solar parallax by observing the close approach to the Earth in 1889 of the minor planets Iris, Victoria and Sappho (his was the standard value for nearly a century). His measurement was repeated by HAROLD SPENCER JONES during...

  18. Schramm, David N (1945-97)

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    Cosmologist, born in St Louis, MO, studied with WILLIAM FOWLER, became professor at the University of Chicago. He was a founder of the subject of `astro-particle physics', studying the particle-physics properties of the Big Bang at the start of the universe. When only two families of particles were known, Schramm predicted from cosmological considerations that there would be just one more family,...

  19. Experimenting with wires, batteries, bulbs and the induction coil: Narratives of teaching and learning physics in the electrical investigations of Laura, David, Jamie, myself and the nineteenth century experimenters. Our developments and instruments

    NASA Astrophysics Data System (ADS)

    Cavicchi, Elizabeth Mary

    Physics is conventionally taught as a fixed curriculum which students must master. This thesis changes that: curriculum emerges from what learners try and question in experiments they invent. The thesis narrates: three adult students exploring wires, batteries and bulbs with me as teacher; nineteenth century investigations of electromagnetism; my laboratory work replicating historic instruments. In each case, learning arose through activity with materials. Evidences of this are analyzed within narratives and reflections. I used teaching-research, a method developed by Duckworth from Piaget's clinical interviewing, to research and simultaneously extend students' evolving understandings. What I learned through questioning students informed my next interactions; what they learned extended their experimenting. Similarly, I researched historical accounts interactively: improvising experiments to develop my understandings. Studying my own learning deepened my interpretations of students' learning. My students Laura, David and Jamie experimented by: soldering bulbs to wires, making series and parallel circuits, inserting resistive wire that dimmed bulbs, conducting electricity through salt water They noticed bulb brightness and battery heat, compared electricity's paths, questioned how voltage and current relate. They inferred electricity's effects manifest magnitudes of material properties. They found their experiences while learning were inseparable from what they learned. I researched investigations connected with Cavendish's leather fish, Galvani's frogs, Schweigger's wire spiraled around a compass needle, Henry's electromagnets, Faraday's induction ring, induction devices of Page, Callan, Hearder. Experimentally, I made galvanometers, electromagnets, induction rings, induction coil. I observed effects of electromagnetism, internal resistance, induced sparking. Across these investigations, learning developed with instrumental innovations; confusions were productive

  20. Hepatozoon cf. terzii (Sambon & Seligman, 1907) infection in the snake boa constrictor constrictor from north Brazil: transmission to the mosquito Culex quinquefasciatus and the lizard Tropidurus torquatus.

    PubMed

    Paperna, I; Lainson, R

    2004-06-01

    Specimens of Hepatozoon-infected Boa constrictor constrictor were obtained from localities in Pará State, north Brazil. Gametocytes in erythrocytes of the peripheral blood measured 10 x 2.5-16.2 x 3.7 microns. They were similar to those described as Haemogregarina terzii by Sambon & Seligmann (1907) in B. c. constrictor, in that they did not distort the infected erythrocyte, and their dimensions approximated those given by Carini (1947). Lungs and liver of infected snakes contained actively dividing meronts of a single type, and cysts containing two to six cystozoites were also present in the liver. Our initial feeding of Culex quinquefasciatus on infected snakes consistently resulted in a heavy death-rate of the engorged mosquitoes, with only a few surviving till the 9th day post feeding. These contained numerous oocysts which were undivided or in early stages of division. A fifth and final experiment, however, provided a few mosquitoes surviving up to 21 days post infection (dpi), and these contained fully sporulated oocysts measuring 190-200 microns in diameter and containing over 60 sporocysts of 19-30 microns in diameter. The number of sporozoites in each sporocyst was estimated as approximately 50. The nature of the parasite's sporogonic cycle in the mosquito thus justifies inclusion of this haemogregarine in the genus Hepatozoon. Two wild-caught specimens of the lizard Tropidurus torquatus were fed with mosquitoes containing fully developed oocysts (21 dpi). When sacrificed, three months later, large numbers of dizoic, tetrazoic and hexazoic cysts were demonstrated in their livers. Cystozoites released from these cysts were shown to possess a conspicuous refractile body.

  1. Wind-fuel cell hybrid project in rural Alaska

    SciTech Connect

    David Lockard

    2000-02-18

    This is a summary of the work performed on the Wind-Fuel Cell Hybrid Project: (1) On October 5th, Tim Howell of the Golden Field Office and Tom Anderson of Battelle Labs arrived in Anchorage. They met with David Lockard, Project Manager, and Percy Frisby, Director of the Alaska Rural Energy Programs Group. (2) On October 6th, Tim, Tom and David flew to Nome to inspect the proposed wind turbine site and meet with John Handeland, Director of the Nome Joint Utility System. They visited the proposed site as well as several private, residential-sized wind turbines operating in the Nome area. (3)Tim and Tom flew to Unalaska on October 7th to meet with Mike Golat, City of Unalaska Public Utility Director, and to inspect the proposed wind turbine sites at Pyramid Creek and Pyramid Valley. (4)Tim sent a scoping letter on December 17th to a variety of local, state and federal agencies requesting comments on the proposed wind turbine project. (5) David discussed this project with Marc Schwartz and Gerry Nix at NREL. Marc provided David with a list of wind prospectors and meteorologists. (6) Tom raised the question of FAA permits for structures over 200 feet tall. Gerry provided information on NREL's experience with FAA permitting on other projects. David summarized the potential turbine choices and heights in a spreadsheet and initiated contact with the Alaska region FAA office regarding the permitting process. (7) David responded to a list of design questions from Tom regarding the project foundations, power output, and size for use in developing the environmental assessment. (8) David tried to get wind data for the Nome Anvil Mountain White Alice site from the Corps of Engineers and the Air Force, but was not able to find any. (9) David solicited quotes from vendors of wind monitoring equipment and provided cost information to Doug Hooker, federal grant manager in preparation for ordering the equipment.

  2. MARC: A Thought Experiment in the Morality of Automated Marking of English

    ERIC Educational Resources Information Center

    Elliott, Victoria

    2014-01-01

    Automated essay scoring programs are becoming more common and more technically advanced. They provoke strong reactions from both their advocates and their detractors. Arguments tend to fall into two categories: technical and principled. This paper argues that since technical difficulties will be overcome with time, the debate ought to be held in…

  3. A CERIF-Compatible Research Management System Based on the MARC 21 Format

    ERIC Educational Resources Information Center

    Ivanovic, Dragan; Milosavljevic, Gordana; Milosavljevic, Branko; Surla, Dusan

    2010-01-01

    Purpose: Entering data about published research results should be implemented as a web application that enables authors to input their own data without the knowledge of the bibliographic standard. The aim of this research is to develop a research management system based on a bibliographic standard and to provide data exchange with other research…

  4. Implementing the Massachusetts Model for Comprehensive School Counseling Programs: A Case Study Examining MARC Award Recipients

    ERIC Educational Resources Information Center

    Salas, Kathryn

    2013-01-01

    Post secondary education is essential to success. To ensure that students who graduate from high school are prepared to make informed decisions about their life after high school, they need to be explicitly taught career development skills. These skills should be part of a comprehensive, results-based, developmentally appropriate comprehensive…

  5. [Development of complex enzymatic preparations of pactinases and celulases for sugar beet marc digestion].

    PubMed

    Bushina, E V; Rozhkova, A M; Zorov, I N; Satrutdinov, A D; Bekkarevich, A O; Koshelev, A V; Okunev, O N; Sinitsyn, A P

    2012-01-01

    Complex enzymatic preparations demonstrating activities homologous to pectinlyase A and heterologous to endo-1,4-beta-glucanase from Penicilliumverruculosum and beta-glycosidase from Aspergillusniger have been obtained on the basis of recombinant strains of the fungus Penicilliumcanescens. Two approaches were utilized: development of an enzymatic preparation on the basis of a new strain, which produced all three enzymes, and development of an enzymatic preparation via combined cultivation of three strains, each of which produced one of the enzymes.

  6. Marcé International Society position statement on psychosocial assessment and depression screening in perinatal women.

    PubMed

    Austin, Marie-Paule

    2014-01-01

    The position statement aims to articulate the arguments for and against universal psychosocial assessment and depression screening, and provide guidance to assist decision-making by clinicians, policy makers and health services. More specifically it: 1. Outlines the general principles and concepts involved in psychosocial assessment and depression screening; 2. Outlines the current debate regarding benefits and risks in this area of practice including the clinical benefits and the ethical, cultural and resource implications of undertaking universal psychosocial assessment in the primary health care setting; 3. Provides a document that will assist with advocacy for the development of perinatal mental health services in the primary care setting. The statement does not set out to make specific recommendations about psychosocial assessment and depression screening (as these will need to be devised locally depending on existing resources and models of care) nor does it attempt to summarise the vast evidence-base relevant to this debate. PMID:24138943

  7. Curriculum-Based Cataloging and the New Metadata: Cataloging beyond the World of MARC

    ERIC Educational Resources Information Center

    Adamich, Tom

    2007-01-01

    From earliest beginnings in the 1990s, cataloging in school libraries is the product of three tasks--listing important details about an item (such as author, size, number of pages), selecting words and phrases that describe the item (such as subject headings, summary notes), and choosing numbers and codes that place the item on the shelf (such as…

  8. Creation of Machine Readable Catalog Entries; An Adaptation of the "Data Preparation Manual: MARC Editors".

    ERIC Educational Resources Information Center

    OCLC Online Computer Library Center, Inc., Dublin, OH.

    The purpose of this manual is to specify the additional steps required in the data collection process to prepare bibliographic data for conversion into machine-readable form. It is designed to aid catalogers in preparing catalog entries in machine readable form for the on-line cataloging system of the Ohio College Library Center. The rules for…

  9. Morphology of the Ebro fan valleys from SeaMARC and sea beam profiles

    USGS Publications Warehouse

    Alonso, B.; Kastens, K.A.; Maldonado, A.; Malinverno, A.; Nelson, C.H.; O'Connell, S.; Palanques, A.; Ryan, William B. F.

    1985-01-01

    The northern continental slope off the Ebro Delta has a badland topography indicating major slope erosion and mass movement of material that deposits sediment into a ponded lobe. The southern slope has a low degree of mass movement activity and slope valleys feed channel levee-complexes on a steep continental rise. The last active fan valley is V-shaped with little meandering and its thalweg merges downstream with the Valencia Valley. The older and larger inactive channel-levee complex is smoother, U-shaped, and meanders more than the active fan valley. ?? 1985 Springer-Verlag New York Inc.

  10. Marcé International Society position statement on psychosocial assessment and depression screening in perinatal women.

    PubMed

    Austin, Marie-Paule

    2014-01-01

    The position statement aims to articulate the arguments for and against universal psychosocial assessment and depression screening, and provide guidance to assist decision-making by clinicians, policy makers and health services. More specifically it: 1. Outlines the general principles and concepts involved in psychosocial assessment and depression screening; 2. Outlines the current debate regarding benefits and risks in this area of practice including the clinical benefits and the ethical, cultural and resource implications of undertaking universal psychosocial assessment in the primary health care setting; 3. Provides a document that will assist with advocacy for the development of perinatal mental health services in the primary care setting. The statement does not set out to make specific recommendations about psychosocial assessment and depression screening (as these will need to be devised locally depending on existing resources and models of care) nor does it attempt to summarise the vast evidence-base relevant to this debate.

  11. The F-MARC study on Ramadan and football: research design, population, and environmental conditions.

    PubMed

    Leiper, John B; Maughan, Ronald J; Kirkendall, Donald T; Bartagi, Zakia; Zerguini, Yacine; Junge, Astrid; Dvorak, Jiri

    2008-12-01

    Ramadan is a month of penance during which Muslims take food or drink only after sunset and before the sun rises. This fast can present a considerable challenge to the Muslim athlete. Sports performance in those who observe Ramadan and those who do not has not been formally compared. Four Tunisian junior football squads participated in the study, and it was the individual's choice whether they observed the Ramadan fast. In this study, 64 players fasted while 36 players did not. Players completed daily questionnaires on perception of training difficulty before and during Ramadan. Anthropometric data were recorded 3 weeks before Ramadan, during the second and fourth weeks of Ramadan, and into the third week after Ramadan. Performance tests (sprint, leg power, agility, aerobic endurance, football-specific skills) were also measured on these test days. Nutritional intake was recorded by recall three times during each phase of the study. Haematological and biochemical analyses were performed on a 7-ml blood sample taken from each participant on each of the test days. Sweat samples were collected during a training session in the third week of Ramadan, when heart rate was also measured. The data analyses are presented and discussed elsewhere in this issue.

  12. Immunomodulating and anti-allergic effects of Negroamaro and Koshu Vitis vinifera fermented grape marc (FGM).

    PubMed

    Marzulli, Giuseppe; Magrone, Thea; Vonghia, Luisa; Kaneko, Masahiro; Takimoto, Hiroaki; Kumazawa, Yoshio; Jirillo, Emilio

    2014-01-01

    Polyphenols contained in FGM from Negroamaro (N) and Koshu (K) Vitis vinifera have been shown to exhibit several immunomodulating activities. For instance, mice affected by experimental colitis when administered with K-FGM showed an attenuation of the inflammatory process. In murine asthma, K-FGM reduced IgE production and eosinophil number in bronchial alveolar lavage fluid. In vitro, both N- and K-FGM were able to induce T regulatory cells in terms of Foxp-3 molecule expression and release of interleukin-10. In another set of experiments both N- and K-FGM were able to balance rate of proliferation/apoptosis/necrosis of normal human peripheral lymphocytes, thus indicating the property of these compounds to maintain immune homeostatic mechanisms in the host. On the other hand, N- and K-FGM inhibited human basophil degranulation, thus, confirming our previous results obtained with rat basophilic leukemia cells. Finally, N- and K-FGM also decreased oxidative burst of human polymorphonuclear cells and monocytes.Taken together, these findings imply the potential clinical usefulness of FGM administration in inflammatory/allergic conditions, such as chronic asthma.

  13. Micro-scale energy valorization of grape marcs in winery production plants.

    PubMed

    Fabbri, Andrea; Bonifazi, Giuseppe; Serranti, Silvia

    2015-02-01

    The Biochemical Methane Potential (BMP) of winery organic waste, with reference to two Italian red and white grapes (i.e. Nero Buono and Greco) by-products was investigated. The study was carried out to verify the possibility to reduce the production impact in a green-waste-management-chain-perspective. The possibility to efficiently utilize wine-related-by-products for energy production at a micro-scale (i.e. small-medium scale winery production plant) was also verified. Results showed as a good correlation can be established between the percentage of COD removal and the biogas production, as the winery can produce, from its waste methanization, about 7800 kW h year(-1) electrical and 8900 kW h year(-1) thermal. A critical evaluation was performed about the possibility to utilize the proposed approach to realize an optimal biomass waste management and an energetic valorization in a local-energy-production-perspective. PMID:25529134

  14. Memoriam for David G. Koch, 1945-2012

    NASA Astrophysics Data System (ADS)

    Borucki, William J.

    2013-01-01

    Dave worked on scientific space instrumentation since the Apollo era in the mid-1960s. He was born and raised in Milwaukee, WI, and attended Milwaukee Lutheran High School where he built a Michelson interferometer that proved to be a stepping-stone for his interest in physics. Dave graduated from the University of Wisconsin-Madison, where he earned a Bachelor of Science in applied mathematics and engineering physics in 1967. As an undergraduate, he worked on balloon-launched sounding rockets and scientific instruments in X-ray and gamma-ray astronomy. At Cornell University, Dave earned a master's degree in 1971, and a doctorate in 1972, both in physics. He built a balloon-borne gamma-ray telescope that detected the first pulsed high-energy gamma rays from the Crab pulsar. In 1972, Dave began his career at American Science and Engineering where he was the project scientist for the Uhuru X-ray satellite. Later, he served as the project scientist for the development of the Einstein Observatory. Dave joined the Smithsonian Center for Astrophysics in 1977 as the project scientist for the Spacelab-2 infrared telescope. There, he served as a co-investigator on the Space Infrared Telescope Facility - IRAC camera proposal, and co-investigator on the Submillimeter Wave Astronomy Satellite, which launched in December 1998. Dave came to NASA Ames Research Center to lead the mission operations for SIRTF and SOFIA (Stratospheric Observatory for Infrared Astronomy) in 1988. He created the Flight Opportunities for Science Teacher EnRichment project. In 1992, Dave began working on what has become the Kepler mission, for which he served as deputy principal investigator until retiring in August 2011. Dave's contributions were many but most notably, he led the development of the Kepler Technology Demonstration used to prove that the transit photometry method would work under on-orbit conditions. Dave loved to build things and was passionate about engaging young hearts and minds with the excitement of science and space exploration. He was particularly fond of educating and empowering teachers with the right tools to connect with the formal and informal classroom.

  15. Frozen in Time: A Response to David Crandall.

    ERIC Educational Resources Information Center

    Finn, Chester E., Jr.

    1989-01-01

    Replies to Crandall's claim that Finn had disrupted a decade of solid research in the Office of Educational Research and Improvement Office (OERI) regional educational laboratories. According to Finn, these labs have wasted taxpayers' money. Currently, states command school policy and finances, and key decision-makers are governors and…

  16. CERT tribal internship program. Final intern report: David Conrad, 1993

    SciTech Connect

    1998-09-01

    The intern`s report contains a Master`s thesis entitled, ``An implementation analysis of the US Department of Energy`s American Indian policy as part of its environmental restoration and waste management mission.`` This thesis examines the implementation of a working relationship between the Nez Perce Tribe and the US Department of Energy`s Office of Environmental Restoration and Waste Management at the Hanford reservation. It examines the relationship using a qualitative methodology and three generations of policy analysis literature to gain a clear understanding of the potential for successful implementation.

  17. Creating a School for David: A Principal's Narrative.

    ERIC Educational Resources Information Center

    Perry, Eleanor A.

    2000-01-01

    A principal recounts her year-long journey to pull a southern Oregon school community together. She used two problem- solving strategies (Situation-Target-Plan and force-field analysis) to alter cultural norms, guide the community through planned change, and integrate staff development, organization development, and action research. (MLH)

  18. David Casarett's Stoned: A Doctor's Case for Medical Marijuana.

    PubMed

    Alger, Bradley E

    2016-01-01

    With legal cannabis sales at $5.4 billion in 2015 and expected to rise by another billion this year in the United States, legalization and marijuana's impact on health is a hot topic of national debate. Casarett, a physician at the University of Pennsylvania, immerses himself in the culture, science, and smoke of medical marijuana in order to sort out the truth behind the buzz. Our reviewer, who has authored more than 120 research papers and reviews on the regulation of synaptic inhibition and endocannabinoids, tell us what the author got right, but also overlooked on his journey to learn more about a complex and controversial subject. PMID:27408675

  19. David Nelson, MD, MPH | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  20. David Florida Laboratory Thermal Vacuum Data Processing System

    NASA Technical Reports Server (NTRS)

    Choueiry, Elie

    1994-01-01

    During 1991, the Space Simulation Facility conducted a survey to assess the requirements and analyze the merits for purchasing a new thermal vacuum data processing system for its facilities. A new, integrated, cost effective PC-based system was purchased which uses commercial off-the-shelf software for operation and control. This system can be easily reconfigured and allows its users to access a local area network. In addition, it provides superior performance compared to that of the former system which used an outdated mini-computer and peripheral hardware. This paper provides essential background on the old data processing system's features, capabilities, and the performance criteria that drove the genesis of its successor. This paper concludes with a detailed discussion of the thermal vacuum data processing system's components, features, and its important role in supporting our space-simulation environment and our capabilities for spacecraft testing. The new system was tested during the ANIK E spacecraft test, and was fully operational in November 1991.

  1. Characteristics of a sandy depositional lobe on the outerMississippi Fan from Sea MARC 1A sidescan sonar images

    USGS Publications Warehouse

    Twichell, D.C.; Schwab, W.C.; Nelson, C.H.; Kenyon, Neil H.; Lee, H.J.

    1992-01-01

    Shows that channelized rather than unconfined transport was the dominant transport mechanism for coarse-grained sediment during the formation of this part of the deep-sea fan. The dendritic distributary pattern and the high order of splaying of the channels, only one of which appears to have been active at a time, suggest that coarse- grained deposits on this fan are laterally discontinuous. -from Authors

  2. Venus analogues on the Earth's ocean floor(?): Volcanic terrains seen by SeaMARC 2 side scan sonar

    NASA Technical Reports Server (NTRS)

    Mouginis-Mark, P. J.; Fryer, P.; Hussong, D.; Zisk, S. H.

    1984-01-01

    The geology of Venus is discussed. The approximate age of the surface and the relative importance of large scale volcanic, tectonic and sedimentary processes are not known. Venus holds a very important role in comparative planetology. The investigation of comparable environments to Venus to test ideas of landform development on that planet are proposed.

  3. [Medecine and chemistry in the context of the Enlightenment: the thesis of the Lausanne physician Marc-Louis Vullyamoz].

    PubMed

    Terrier, Georges

    2003-01-01

    The chemico-medical essay "De sale lactis essentiali" is a thesis presented in Leyden in 1756 by a physician from Lausanne, M.-L. Vullyamoz, to obtain the medical degree. It shows that chemistry has become a university science connected with medicine and that combustion was explained at that time by G. E. Stahl's theory of the phlogiston. It reminds us that the hypotheses of this German physician, which were part of the animistic doctrine, were widely adopted in Europe. In chemistry they began to fade in 1789 after the publication of Lavoisier's work on oxydation. Nevertheless, they have contributed to establish a modern science. In medicine Stahl's animism evolved towards vitalism, which survived in several forms. Vullyamoz's thesis, which presents chemical experiences intended to analyse and promote a popular medicine, is a testimony of the spirit of Enlightenment, which rejects dogmatism and tries to understand facts through observation and the use of reason. PMID:15030051

  4. Henry David Thoreau, Forest Succession & The Nature of Science: A Method for Curriculum Development

    ERIC Educational Resources Information Center

    Howe, Eric M.

    2009-01-01

    A main reason for using the history of science in classroom instruction is its utility in promoting students' understanding of the nature of science (NOS). As indicated in such documents as the "National Science Education Standards," it is important to help students develop their understanding of NOS so that they will become more critical…

  5. David Coleman and the Technologisation of the Common Core: A Critical Discourse Analysis

    ERIC Educational Resources Information Center

    Johnson, Lindy L.

    2014-01-01

    Drawing on sociocultural perspectives and New Literacies Studies this study uses Critical Discourse Analysis (CDA) as a tool to closely analyse one way the Common Core State Standards in the United States are being produced, disseminated and consumed. The analysis focuses on a section of the CCSS, a model lesson given by one of the primary…

  6. Comment on "A petrologic assessment of internal zonation in granitic pegmatites" by David London (2014)

    NASA Astrophysics Data System (ADS)

    Thomas, Rainer; Davidson, Paul

    2015-01-01

    London (2014) provides an interesting article which presents a study of pegmatite zonation which is of considerable interest to students of pegmatites. However, although there is much to recommend it we take exception to his attempts to dismiss an extensive body of work on the use of melt inclusions to address the critical question of actual melt compositions during the evolution of pegmatites. Volatiles are by definition fugitive, since they are readily lost by degassing, and yet they are clearly critical to the growth of the large crystals which are a defining characteristic of pegmatites (e.g. Bartoli et al., 2014; Bowen, 1956; London, 2008; Lowenstern, 2003). Any research technique which can address the pre-degassing melt compositions should therefore be considered on its merits. Although melt inclusion studies are of relatively recent vintage the problems and possible questions of interpretation have been addressed in considerable detail for at least the last two decades (e.g. Lowenstern, 2003, and references therein) and recently in Audétat and Lowenstern (2014). Likewise, any discussion needs to cover "simple" quartz-feldspar-muscovite pegmatites (e.g. Thomas et al., 2009b), as well as the much less common if more interesting rare-element rich pegmatites (e.g. Thomas et al., 2009a).

  7. 78 FR 38363 - David A. Ruben, M.D.; Decision and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... DK's compliance with her treatment even after he was aware of her cocaine addiction.' '' R.D. at 50..., 74 FR 10083, 10094 (2009). The ALJ's Rulings on the Government's Motion in Limine To Exclude Evidence.... Co., 2 Cal. Rptr. 3d 135, 155 (Cal. Ct. App. 2003); Robert L. Dougherty, 76 FR 16823, 16830...

  8. 76 FR 9005 - David Creasey; Notice of Application Tendered for Filing With the Commission; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-16

    ... Creek; (2) a 1,650-foot-long, 21-inch-diamter PVC penstock with an intake structure and trashrack; (3...-long, 12-inch-diamater PVC pipe which would return flows to the Lincoln Creek Drainage Ditch; and...

  9. David Adler Award Talk: Half-Metals, Spin Torque, and Nanorings

    NASA Astrophysics Data System (ADS)

    Chien, C. L.

    2004-03-01

    New phenomena in magnetic nanostructures, some of which have led to important technological applications in magnetoelectronics, have been realized in rapid succession in recent years. Several examples will be described in this talk. While most ferromagnetic metals are partially spin-polarized, the half-metallic ferromagnets (HMF) with only one spin band at the Fermi energy have the highest possible spin polarization of 100%. Although HMFs were theoretically predicted in 1983, they were not experimentally identified until recently using the few techniques with which the spin polarization of a metal can be determined. A spin-polarized current with its substantial angular momentum can cause spin precession and even switching in a receiving ferromagnetic entity. Aspects of the spin torque effect, as observed in continuous multilayered films as well as single-layer ferromagnetic films with a point contact, will be described. Magnetic nanorings have been proposed theoretically to alleviate problems due to the singularity at the center of a small ferromagnetic disc in the vortex state. Previous attempts on nanorings using e-beam lithography have been limited by the small number of rings of relatively large diameters ( ˜1 μm). Recently, we have developed a new lithography-less method for making arrays of a large number (10^9) of sub-100 nm nanorings, either single-layer or multilayered, with very high areal density (45 rings/μm^2). Some of the results of arrays of Co nanorings will be described. *I am very fortunate to be working with talented students and post-docs (F. Y. Yang now at Ohio State University, Y. Ji now at Argonne National Lab., G. Strijkers now at Einhoven Institute of Technology, Q. Zhu, D. L. Fan, and T. Y. Chen), some of whose results are included here. I am also indebted to G. Xiao (Brown University), J. G. Zhu (Carnegie-Mellon University), M. D. Stiles (NIST), A. Gupta (IBM), and J. M. Byers (NRL) for the privileges of collaboration, and NSF for financial support.

  10. The Sir David Cuthbertson Medal Lecture. Hunting for new pieces to the complex puzzle of obesity.

    PubMed

    Frühbeck, Gema

    2006-11-01

    Disentangling the neuroendocrine systems that regulate energy homeostasis and adiposity has been a long-standing challenge in pathophysiology, with obesity being an increasingly important public health problem. Adipose tissue is no longer considered a passive bystander in body-weight regulation. It actively secretes a large number of hormones, growth factors, enzymes, cytokines, complement factors and matrix proteins, at the same time as expressing receptors for most of these elements, which influence fuel storage, mobilisation and utilisation at both central and peripheral sites. Thus, an extensive cross talk at a local and systemic level in response to specific external stimuli or metabolic changes underpins the multifunctional characteristics of adipose tissue. In addition to the already-known adipokines, such as IL, TNFalpha, leptin, resistin and adiponectin, more recently attention has been devoted to 'newcomers' to the 'adipose tissue arena', which include aquaporin, caveolin, visfatin, serum amyloid A and vascular endothelial growth factor. While in vitro and in vivo experiments have provided extremely valuable information, the advances in genomics, proteomics and metabolomics are offering a level of information not previously attainable to help unlock the molecular basis of obesity. The potential and power of combining pathophysiological observations with the wealth of information provided by the human genome, knock-out models, transgenesis, DNA microarrays, RNA silencing and other emerging technologies offer a new and unprecedented view of a complex disease, conferring novel insights into old questions by identifying new pieces to the unfinished jigsaw puzzle of obesity.

  11. 78 FR 76392 - Hours of Service of Drivers: Application for Exemption; David Muresan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-17

    ... published on January 17, 2008 (73 FR 3316). Public Participation: The Federal eRulemaking Portal is... shifts required for drivers of property-carrying CMVs (68 FR 22456; April 28, 2003). However, drivers of... employ), including ``rest'' and ``sleep.'' Mr. Muresan believes that the Agency's HOS rules do...

  12. Video-atlas on minimally invasive mitral valve surgery-The David Adams technique.

    PubMed

    Castillo, Javier G; Milla, Federico; Anyanwu, Anelechi C; Adams, David H

    2013-11-01

    Median sternotomy has unquestionably evolved over recent decades. Modern sternotomy involves a 7-8 cm lower midline skin incision, tunneling of the subcutaneous tissues with subsequent creation of myocutaneous flaps, full sternotomy, and standard cardiopulmonary bypass techniques with central cannulation. In experienced centers, modern sternotomy may achieve all the goals of minimally invasive surgery, including excellent cosmesis, excellent postoperative pain control, low rates of bleeding and transfusion (our re-exploration rate for bleeding is <1%), and the ability to perform any reconstructive technique that would be used in a standard sternotomy, with very high repair rates (our most recent series documented a repair rate exceeding 99% in an all-comers population of degenerative disease regardless of complexity).

  13. Sean and David Goldman International Child Abduction Prevention and Return Act of 2014

    THOMAS, 113th Congress

    Sen. Menendez, Robert [D-NJ

    2014-06-19

    06/19/2014 Read twice and referred to the Committee on Foreign Relations. (All Actions) Notes: For further action, see H.R.3212, which became Public Law 113-150 on 8/8/2014. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  14. Sean and David Goldman International Child Abduction Prevention and Return Act of 2013

    THOMAS, 113th Congress

    Rep. Smith, Christopher H. [R-NJ-4

    2013-05-13

    06/14/2013 Referred to the Subcommittee on Crime, Terrorism, Homeland Security, and Investigations. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  15. Photographic region elemental abundance analyses of Dr. David S. Leckrone's GTO HST stars 2

    NASA Technical Reports Server (NTRS)

    Adelman, Saul J.

    1994-01-01

    Activities are presented for the grant-funded work at the Dominion Astrophysical (DAO) and Casleo Observatories. A comparison is planned for the spectrograms taken at both observatories of similar stars. It is reported that of the Northern Hemisphere program stars, only 112 Her remains to be analyzed. A preliminary solution for the components of this binary system has been found. The new ATLAS9 models have been used to reevaluate the effective temperatures and surface gravities derived for all program stars. Model atmospheres are being calculated by extensive grids on workstations upgraded to the DEC 3000 model 300X running Open VMS. An attached paper describes a plan to obtain the needed gf values as well as some first applications of astrophysical gf values, the most important of which was Vega.

  16. 78 FR 36591 - David M. Lewis, D.M.D., Dismissal of Proceeding

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-18

    ....'' Ronald J. Riegel, 63 FR 67132, 67133 (1998); see also William W. Nucklos, 73 FR 34330 (2008). So too..., 73 FR at 34330. Accordingly, there is neither a registration, nor an application, to act upon, and... circumstances indicating the intent of'' his client, In re Focus Media Inc., 387 F.3d 1077, 1082 (9th Cir....

  17. Brilliant Ideas for Using ICT in the Inclusive Classroom. David Fulton/Nasen

    ERIC Educational Resources Information Center

    McKeown, Sally; McGlashon, Angela

    2012-01-01

    This practical teachers' guide will help you to unlock the enormous potential of new technology in order to enhance pupils' learning, particularly for young people with additional needs. Written by two of the UK's leading technology experts, this new resource will enable you to use ICT effectively to make lessons more accessible, motivating and…

  18. The 2010 ESPEN Sir David Cuthbertson Lecture: new and old proteins: clinical implications.

    PubMed

    McCoy, Rozalina G; Nair, K Sreekumaran

    2013-10-01

    The past century had witnessed vast advances in biomedical research, particularly in the fields of genomics and proteomics, yet the translation of these discoveries into clinical practice has been hindered by gaps in mechanistic understanding of variability governing disease susceptibility and pathogenesis. Among the greatest challenges are the dynamic nature of the proteome and the imperfect methodologies currently available to study it. Here, we review key recently developed proteomic techniques that have allowed for dynamic characterization of protein quality, as well as quantity, and discuss their potential applications in understanding aging and metabolic disorders including diabetes. These methodologies revealed that senescence is characterized, in part, by decreased rates of de novo protein synthesis and potentially also degradation, in addition to concomitantly increased levels of oxidative stress, ultimately resulting in excessive accumulation of damaged and dysfunctional proteins. Insulin may be a key mediator in these pathologies, as hyperinsulinemia has been shown to hinder protein degradation while transient insulin deficiency may accelerate oxidative damage. We also discuss two interventions that have been proposed to delay, and possibly reverse, senescence by augmenting protein degradation: chronic caloric restriction and aerobic exercise. PMID:23481224

  19. Teaching Organic Unity: An Example Based on "The Ball," a Poem by David Ramirez.

    ERIC Educational Resources Information Center

    May, Charles E.

    1971-01-01

    The way in which analysis of a poem can increase the student's enjoyment of it is illustrated and discussed. The teacher is offered one short poem, written by a fifth grade student, which can be used as an exercise in poem analysis. It is believed that the poem analyzed, "The Ball," which is comprised of 11 words, is effective as an introduction…

  20. 75 FR 146 - Proposed Cercla Administrative Cost Recovery Settlement; David Benvenuti and Howe Cleaners, Howe...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ... given of a proposed administrative settlement for recovery of past costs concerning the Howe Cleaners... withdraw its consent to the settlement if comments received disclose facts or considerations which...

  1. Molecular Toxicology (by P. David Josephy, with Bengt Mannervik and Paul Ortiz de Montellano)

    NASA Astrophysics Data System (ADS)

    Havrilla, Christine; Porter, Ned A.

    1998-05-01

    Oxford University Press: Oxford and New York, 1997. xv + 368 pp. ISBN 0-19-509340-2. $56.00. This well-written book presents concepts of toxicology from a chemical, biochemical, and molecular biological perspective and serves as a welcome companion to other books on toxicology, which tend to have as a basis the characterization and quantification of toxic responses. This mechanistic approach should be particularly appealing to scientists with a strong chemical background. The book is an outgrowth of a course in molecular toxicology taught at the University of Guelph by the author, and it fills a much-needed niche as a textbook for a course focusing on biochemical mechanisms of toxicology. The clientele for such a course is advanced undergraduates or graduate students with a strong background in biochemistry, bioorganic chemistry, toxicology, or pharmacology.

  2. David Adler Lectureship Award in the Field of Materials Physics Talk: Surfaces of Quasicrystals

    NASA Astrophysics Data System (ADS)

    Thiel, Patricia

    2010-03-01

    Quasiperiodic order is recognized (in a utilitarian, rather than a mathematical sense) by the absence of periodicity, concurrent with a classically-forbidden rotational symmetry. It is quite beautiful, having captured the attention of scientists and artists alike. Following the discovery of quasiperiodic order in a real system,footnotetextD. Shechtman, I. Blech, D. Gratias, and J.W. Cahn, Phys. Rev. Lett. 53, 1951 (1984). many metallic alloys and intermetallics were found to exhibit this type of order on the atomic scale. More recently ``soft'' quasicrystals were discovered,footnotetextL. Bindi, P.J. Steinhardt, N. Yao, and P.J. Lu, Science 324, 1306 (2009). and nanocrystalline arrays were found to spontaneously adopt quasiperiodic order.footnotetextD.V. Talapin, E.V. Shevchenko, M.I. Bodnarchuk, X. Ye, J. Chen, and C.B. Murray, Nature 461 , 964 (2009). From a scientific perspective, quasicrystals are alluring because they allow us to test the relationship between atomic structure and physical properties. This talk deals with the ways in which our understanding of solid surfaces has been both enriched and challenged by these complex materials.footnotetextP. Thiel, Annu. Rev. Phys. Chem. (2008).^,footnotetextV. Fourn'ee, J. Ledieu, and P. Thiel, J. Phys: Condens. Matter. 20, 3310301 (2008). properties of the metallic quasicrystals originally generated interest because they were unusual.footnotetextJ.M. Dubois, Useful Quasicrystals(World Scientific, Singapore, 2005). For instance, among Al-rich alloys, the Al-based quasicrystalline phases exhibit puzzling resistance to surface oxidation. Also, Al-rich quasicrystals have surprisingly good and promising catalytic properties (e.g. for steam reforming of methanol).footnotetextA.P. Tsai and M. Yoshimura, Appl. Cat. A: General 214 , 237 (2001). Perhaps most famously, they exhibit low friction.^7 Comparisons with crystalline materials have established that these features are deeply related to the quasiperiodic atomic structure. talk focuses, first, on the ways that surfaces of quasicrystals are unusual templates for adsorption and solid film growth.footnotetextV. Fourn'ee and P.A. Thiel, J. Phys. D: Appl. Phys. 38, R83 (2005). They can enforce quasicrystalline structure in films,footnotetextK.J. Franke, H.R. Sharma, W. Theis, P. Gille, P. Ebert, and K.H. Rieder, Phys. Rev. Lett. 89, 156104 (2002). opening the door to exploration of the properties of materials in such an ``unnatural'' state. The electronic structure at quasicrystal surfaces can affect film morphology through a quantum size effect.footnotetextV. Fourn'ee, H.R. Sharma, M. Shimoda, A.P. Tsai, B. Unal, A.R. Ross, T.A. Lograsso, and P.A. Thiel, Phys. Rev. Lett. 95, 155504 (2005).^,footnotetextB. "Unal, V. Fourn'ee, P.A. Thiel, and J.W. Evans, Phys. Rev. Lett. 102, 196103 (2009). Quasicrystal surfaces have broad ensembles of adsorption sites,footnotetextB. "Unal, C.J. Jenks, and P.A. Thiel, J. Phys: Condens. Matter. 21, 055009 (2009). including trap sites that may lead to quasi-periodic arrays of islands.footnotetextT. Cai, J. Ledieu, R. McGrath, V. Fourn'ee, T.A. Lograsso, A.R. Ross, and P.A. Thiel, Surface Sci. 526, 115 (2003).^,footnotetextB. Unal, V. Fourn'ee, K.J. Schnitzenbaumer, C. Ghosh, C.J. Jenks, A.R. Ross, T.A. Lograsso, J.W. Evans, and P.A. Thiel, Phys. Rev. B 75, 064205 (2007). This talk also focuses on their low friction, when measured with techniques that probe macroscopic scales (conventional pin-on-disk tribometers) to nanoscopic scales (atomic force microscopy).footnotetext5. J.Y. Park, D.F. Ogletree, M. Salmeron, R.A. Ribeiro, P.C. Canfield, C.J. Jenks, and P.A. Thiel, Science , 1354 (2005).

  3. A captured asteroid : Our David's stone for shielding earth and providing the cheapest extraterrestrial material

    NASA Astrophysics Data System (ADS)

    Massonnet, Didier; Meyssignac, Benoît

    2006-07-01

    The issue of protecting the Earth against an asteroid impact is very popular and many concepts have been proposed to fulfil this objective. In this paper, we develop the idea of capturing a small size asteroid from an orbit close to Earth's in terms of energy and placing it into a loose Earth-bound orbit in order to use it as a shield by engineering its collision with any incoming, threatening body prior to its impact with the Earth. The operations for turning the captured asteroid into an efficient shield appear to be quicker, easier, cheaper and safer than an mission aimed at landing on an incoming impact-bound asteroid either for altering its trajectory or attempting to destroy it. The aim is an asteroid typically 20 40 m in diameter, too small to cause damage on Earth if an improper management leads to its crash, but big enough to destroy and deviate any incoming body if a collision is engineered with it preferably at more than one million km from Earth. Such a collision could be implemented within a 8 month time frame. Such an asteroid would also be a source of material such as liquid oxygen for exploratory missions. We show that the production of this material is much more efficient from an asteroid's surface than from the Moon's. As the celestial surface most accessible from Earth, a captured asteroid is also easier to engineer. Several thousands of tons of oxygen might become available sitting on the outer rim of Earth's gravity field. We examine the advantages and drawbacks of this concept and we propose a stepped approach for making it a reality within a foreseeable future. Key factors are first the detection of a candidate, whose small size make it difficult to spot, among a population of asteroids easy to reach from the Earth. We have identified such a potential candidate in 2000SG344 and describe the parameters of its capture. The second key point is how to deviate the candidate into an loose Earth bound orbit. Our preferred concept is to deposit a small robotic instrument aimed at throwing up matter gathered on the surface of the body with typical velocities of tens of meters per second. The robot would require a year and a few hundreds of watts continuously to alter the velocity of the asteroid in such a way as to inject it through an Earth Sun Lagrange point, and then to control a Lagrangian quasi-periodic orbit with a typical 6-month period. We conclude that such an enterprise is far from being unfeasible and that it can probably be conducted using today's systems and exploratory tools in a few years time frame.

  4. GSRP/David Marshall: Fully Automated Cartesian Grid CFD Application for MDO in High Speed Flows

    NASA Technical Reports Server (NTRS)

    2003-01-01

    With the renewed interest in Cartesian gridding methodologies for the ease and speed of gridding complex geometries in addition to the simplicity of the control volumes used in the computations, it has become important to investigate ways of extending the existing Cartesian grid solver functionalities. This includes developing methods of modeling the viscous effects in order to utilize Cartesian grids solvers for accurate drag predictions and addressing the issues related to the distributed memory parallelization of Cartesian solvers. This research presents advances in two areas of interest in Cartesian grid solvers, viscous effects modeling and MPI parallelization. The development of viscous effects modeling using solely Cartesian grids has been hampered by the widely varying control volume sizes associated with the mesh refinement and the cut cells associated with the solid surface. This problem is being addressed by using physically based modeling techniques to update the state vectors of the cut cells and removing them from the finite volume integration scheme. This work is performed on a new Cartesian grid solver, NASCART-GT, with modifications to its cut cell functionality. The development of MPI parallelization addresses issues associated with utilizing Cartesian solvers on distributed memory parallel environments. This work is performed on an existing Cartesian grid solver, CART3D, with modifications to its parallelization methodology.

  5. The Fiction of the Standard of Taste: David Hume on the Social Constitution of Beauty

    ERIC Educational Resources Information Center

    Stradella, Alessandra

    2012-01-01

    This article submits the idea that, beyond traditional readings of the essay, Hume's "Of the Standard of Taste" is an intimation to appreciate the fictional nature of the standard of taste and our aesthetic education thereof. It is argued that, with Hume, art is not for the benefit and enjoyment of the individual. One's private response to beauty…

  6. Video-atlas on minimally invasive mitral valve surgery—The David Adams technique

    PubMed Central

    Castillo, Javier G.; Milla, Federico; Anyanwu, Anelechi C.

    2013-01-01

    Median sternotomy has unquestionably evolved over recent decades. Modern sternotomy involves a 7-8 cm lower midline skin incision, tunneling of the subcutaneous tissues with subsequent creation of myocutaneous flaps, full sternotomy, and standard cardiopulmonary bypass techniques with central cannulation. In experienced centers, modern sternotomy may achieve all the goals of minimally invasive surgery, including excellent cosmesis, excellent postoperative pain control, low rates of bleeding and transfusion (our re-exploration rate for bleeding is <1%), and the ability to perform any reconstructive technique that would be used in a standard sternotomy, with very high repair rates (our most recent series documented a repair rate exceeding 99% in an all-comers population of degenerative disease regardless of complexity). PMID:24349990

  7. David, Mr Bear and Bernstein: Searching for an Equitable Pedagogy through Guided Group Work

    ERIC Educational Resources Information Center

    Boyle, Bill; Charles, Marie

    2012-01-01

    The authors' experiences of observing teaching and learning in schools have led them to become concerned at the dominant paradigm of a "pedagogy of poverty" at the expense of a "pedagogy of plenty". Bernstein's theory of power and control of education knowledge is overtly practised in classrooms globally. This is evidenced in the narrowing of the…

  8. Petit Receives 2003 David Perlman Award for Excellence in Science Journalism - News

    NASA Astrophysics Data System (ADS)

    Perlman, David

    2004-02-01

    Charles W. Petit received the Perlman Award at the AGU Fall Meeting Honors Ceremony, which was held on 10 December 2003, in San Francisco, California. The award honors ``a single article or radio/television report that makes geophysical material accessible and interesting to the general public''.

  9. Makers of Modern Science. Volume 9, Linus Pauling: Scientist and Advocate by David E. Newton

    NASA Astrophysics Data System (ADS)

    Kauffman, George B.; Kauffman, Laurie M.

    1997-04-01

    Facts on File: New York, 1994. 136 pp. Figs. and photos. 15.0 x 22.6 cm. $16.95 Makers of Modern Science, a series of biographies (available on standing order at a 20% discount), explores the lives and achievements of scientists who have made the greatest contributions to human knowledge during the 19th and 20th centuries. Each scientist's achievements, including underlying scientific principles, are discussed simply and clearly and are free of technical jargon. Drawing on primary sources such as diaries, memoirs, letters, and contemporary news stories, as well as secondary sources, each volume depicts the human drama of scientific work, the excitement and frustration of research, and the exhilaration and rewards of discovery. Each book, which includes black-and-white photographs, diagrams, an annotated bibliography, and a detailed index, contains a final chapter summarizing the legacy of the scientist's achievements.

  10. Leading change from the top line. Interview by Thomas A Stewart and David Champion.

    PubMed

    Hassan, Fred

    2006-01-01

    Most CEOs who specialize in turning around struggling companies focus on costs. But for Fred Hassan, chairman and CEO of Schering-Plough, the primary focus in a turnaround is the top line. Since 2003, when Hassan took the helm at the global pharmaceutical company, he has overseen a remarkable recovery in performance. And consistent with his philosophy, the turnaround started with sales. Considering sales reps as less than crucial to strategy, Hassan cautions, is a big mistake. At Schering-Plough, he has concentrated on motivating and organizing salespeople to create trusting relationships with doctors. "You have to differentiate the salesperson in the customer's mind--just like you differentiate brands," he explains. A doctor may see 60 pharmaceutical reps on a regular basis but actually trust far fewer. To earn a spot in this inner circle, Schering-Plough reps try to turn each customer encounter into an occasion to help doctors provide better care for their patients. Schering-Plough also restructured its sales forces so that reps carry not just one kind of product, as they do in most pharmaceutical companies, but several. Covering a broad range of treatments gives reps more ways to build value-adding relationships with doctors. In this interview, Hassan discusses his success at Schering-Plough and his experiences at other pharmaceutical companies. During his career, he has built a reputation for being in tune with the front lines, as well as for reaching out to the managers who supervise salespeople. He has found that this level of personal attention not only makes reps feel respected but also gives him valuable strategic insights.

  11. Independent Verification Final Summary Report for the David Witherspoon, Inc. 1630 Site Knoxville, Tennessee

    SciTech Connect

    P.C. Weaver

    2009-04-29

    The primary objective of the independent verification was to determine if BJC performed the appropriate actions to meet the specified “hot spot” cleanup criteria of 500 picocuries per gram (pCi/g) uranium-238 (U-238) in surface soil. Specific tasks performed by the independent verification team (IVT) to satisfy this objective included: 1) performing radiological walkover surveys, and 2) collecting soil samples for independent analyses. The independent verification (IV) efforts were designed to evaluate radioactive contaminants (specifically U-238) in the exposed surfaces below one foot of the original site grade, given that the top one foot layer of soil on the site was removed in its entirety.

  12. Beyond Conservation and Liberation: The Education of Our Aspirations. Thirteenth David Dodds Henry Lecture.

    ERIC Educational Resources Information Center

    Wilson, Linda S.

    This booklet presents the text of a lecture by Linda S. Wilson, president of Radcliffe College (Cambridge, Massachusetts) on the role of higher education as well as the responses, questions and discussion that followed. The lecture is preceded by a preface and an introduction by Morton W. Weir, chancellor of the University of Illinois at…

  13. David Adler Lectureship Award in the Field of Materials Physics Lecture

    NASA Astrophysics Data System (ADS)

    Bredas, Jean-Luc

    2013-03-01

    We first review the current state-of-the-art in the field of organic electronics and then focus on organic solar cells, which we define as solid-state cells in which the semiconducting materials between the electrodes are organic, be them polymers, oligomers, or small molecules. We describe the optical and electronic processes that take place in such cells and turn our attention briefly to: (i) optical absorption and exciton formation; (ii) exciton migration to the electron donor - electron acceptor interface; (iii) exciton dissociation into charge carriers, resulting in the appearance of holes in the donor component and electrons in the acceptor component; (iv) charge carrier mobility; and (v) charge collection at the electrodes. In the second part of the presentation, we underline the complexity of the processes taking place at the nanoscale at the donor/acceptor interfaces and highlight the molecular understanding that comes from a computational approach combining electronic-structure theory calculations, molecular mechanics / molecular dynamics simulations, and Monte Carlo simulations.

  14. David Adler Lectureship Award in the Field of Materials Physics Talk: Novel Nitride and Oxide Electronics

    NASA Astrophysics Data System (ADS)

    Pearton, Stephen

    2011-03-01

    Recent progress in development of GaN-based transistors for gas and bio-sensing applications and amorphous IGZO layers for use thin film transistors (TFTs)on flexible substrates, including paper,will be presented. For the detection of gases such as hydrogen, the gateless GaN transistors are typically coated with a catalyst metal such as Pd or Pt to increase the detection sensitivity at room temperature. Functionalizing the surface with oxides, polymers and nitrides is also useful in enhancing the detection sensitivity for gases and ionic solutions.The use of enzymes or adsorbed antibody layers on the semiconductor surface leads to highly specific detection of a broad range of antigens of interest in the medical and security fields. We give examples of recent work showing sensitive detection of glucose, lactic acid, prostate cancer and breast cancer markers and the integration of the sensors with wireless data transmission systems to achieve robust, portable sensors. The amorphous transparent conducting oxide InZnGaO4 (IGZO) is attracting attention because of its high electron mobility (10-50 cm2.V-1.sec-1), high transparency in the visible region of the spectrum and its ability to be deposited with a wide range of conductivities.This raises the possibility of making low-cost electronics on a very wide range of arbitrary surfaces, including paper and plastics. N-type oxides such as zinc oxide, zinc tin oxide, indium gallium oxide, and indium gallium zinc tin oxide (IGZO) exhibit surprisingly high carrier mobilities even for amorphous films deposited at 300K. This has been explained by the fact that the conduction in these materials is predominantly through non-directional s orbitals which are less affected by disorder than the directional sp3 orbitals which control electron transport in Si. Examples of progress and discussion of remaining obstacles to use of IGZO TFTs will be presented Work performed in collaboration with Fan Ren.

  15. 78 FR 10608 - David Grant United States Air Force Medical Center Specialty Care Travel Reimbursement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-14

    ... adequate clinical case mix of patients for approved Graduate Medical Education program functioning in the... demonstration would be initially conducted at DGMC and its satellite clinic, the McClellan Clinic (MCC) as well as the clinic located at Beale Air Force Base (Beale). However, it could be expanded to other...

  16. Ethnography, Step by Step (2nd Edition), by David M. Fetterman, Thousand Oaks, Ca: Sage, 1998..

    ERIC Educational Resources Information Center

    Green, Jennifer C.; Buell, James

    2000-01-01

    Reviews this edition, which like the first is primarily an organized presentation of fieldwork vignettes and instructive examples from research and evaluation contexts. The presentation is organized by the steps involved in ethnographic fieldwork. This edition is updated with references to electronic technology. (SLD)

  17. Experiential Learning: From Discourse Model to Conversation. Interview with David Kolb.

    ERIC Educational Resources Information Center

    Hamalainen, Kauko; Siirala, Eeva

    1998-01-01

    In this interview, Kolb, developer of the experiential learning cycle model, explores learning motivation, aspects of conversation (as experiential learning and as evaluation), and standardization versus diversity in education. (SK)

  18. Designing a Utopia: An Architectural Studio Experience on David Harvey's "Edilia"

    ERIC Educational Resources Information Center

    Yesilkaya, Nese Gurallar

    2008-01-01

    The design of a utopia was devised as a studio project in order to bring critical thinking into the design studio and to stimulate creativity. By suggesting a utopia, the pedagogical aim was to improve progressive thinking and critical thought in the design education of architectural students -- and also future architects. From this perspective,…

  19. Creating Multisensory Environments: Practical Ideas for Teaching and Learning. David Fulton/Nasen

    ERIC Educational Resources Information Center

    Davies, Christopher

    2011-01-01

    Multi-sensory environments in the classroom provide a wealth of stimulating learning experiences for all young children whose senses are still under development. "Creating Multisensory Environments: Practical Ideas for Teaching and Learning" is a highly practical guide to low-cost cost, easy to assemble multi-sensory environments. With a…

  20. David M. Hume Memorial Lecture. An overview of the stroke problem in the carotid territory.

    PubMed

    Callow, A D

    1980-08-01

    In a review of 1,000 carotid endarterectomies performed over a 20 year period, there was relief of transient ischemic attacks in approximately 85% of patients, an operative mortality of 1.3%, due almost exclusively to myocardial infarction, and a recurrent stenosis rate of 3.1%. Coexisting cardiac disease constitutes the greatest operative hazard. Continuous electroencephalographic monitoring is a reliable method of detecting inadequate cerebral perfusion during carotid cross clamping and for the selective use of a temporary inlying carotid shunt. An atherosclerotic plaque in the carotid system constitutes a greater risk than elsewhere in the peripheral arterial system and should not be considered an innocent lesion. Prophylactic carotid endarterectomy can be performed with almost no mortality and morbidity. Antiplatelet agents, while useful in reducing the incidence of transient ischemic attacks, do not seem to provide equal protection against stroke and death from stroke.

  1. David M. Hume Memorial Lecture. Impact of endovascular technology on the practice of vascular surgery.

    PubMed

    Veith, F J; Marin, M L

    1996-08-01

    Endovascular treatment techniques have already replaced some vascular operations. The likelihood is that new endovascular techniques involving stents and stented grafts will replace additional vascular operations. All these treatments involve the use of catheter-guidewire, balloon, and imaging modalities, particularly digital fluoroscopy. These modalities have already and will increasingly help to improve and simplify standard vascular operations such as thromboembolectomy, infrainguinal bypasses, and management of aneurysms and arteriovenous fistulas. Accordingly, vascular surgeons must become familiar with and use these endovascular methods and techniques. This can be accomplished in a variety of ways which includes working as part of a multidisciplinary vascular treatment group in which various specialists collaborate to provide the best, most cost-effective care to vascular disease patients.

  2. David Hume's no-miracles argument begets a valid No-Miracles Argument.

    PubMed

    Howson, Colin

    2015-12-01

    Hume's essay 'Of Miracles' has been a focus of controversy ever since its publication. The challenge to Christian orthodoxy was only too evident, but the balance-of-probabilities criterion advanced by Hume for determining when testimony justifies belief in miracles has also been a subject of contention among philosophers. The temptation for those familiar with Bayesian methodology to show that Hume's criterion determines a corresponding balance-of-posterior probabilities in favour of miracles is understandable, but I will argue that their attempts fail. However, I show that his criterion generates a valid form of the so-called No-Miracles Argument appealed to by modern realist philosophers, whose own presentation of it, despite their possession of the probabilistic machinery Hume himself lacked, is invalid.

  3. Using Playful Practice to Communicate with Special Children. David Fulton/Nasen

    ERIC Educational Resources Information Center

    Corke, Margaret

    2011-01-01

    Playfulness is important; it creates an alternative space where emotional, cognitive and social dimensions can be explored and tested. This highly practical book explores the endless possibilities of using playful, creative and interactive activities to meaningfully engage with children with multiple learning difficulties or autistic spectrum…

  4. Finding a New Vision of Gifted Education: An Interview with David Yun Dai

    ERIC Educational Resources Information Center

    Henshon, Suzanna E.

    2013-01-01

    Zijiang lecture professor of education and psychology at East China Normal University. Dr. Dai has published seven books and over 70 journal articles, book chapters, encyclopedia entries, and book and…

  5. David Meets Goliath on the Information Superhighway: Venezuela in the Context of the Electronic Communication Networks.

    ERIC Educational Resources Information Center

    Sanchez-Vegas, Saadia

    1995-01-01

    Discusses Venezuela's information and communications technology infrastructure and usage patterns; examines future networking plans; and addresses political and economic considerations linked to the information and technology problems in Venezuela and in Latin America in general. (LRW)

  6. Leading change from the top line. Interview by Thomas A Stewart and David Champion.

    PubMed

    Hassan, Fred

    2006-01-01

    Most CEOs who specialize in turning around struggling companies focus on costs. But for Fred Hassan, chairman and CEO of Schering-Plough, the primary focus in a turnaround is the top line. Since 2003, when Hassan took the helm at the global pharmaceutical company, he has overseen a remarkable recovery in performance. And consistent with his philosophy, the turnaround started with sales. Considering sales reps as less than crucial to strategy, Hassan cautions, is a big mistake. At Schering-Plough, he has concentrated on motivating and organizing salespeople to create trusting relationships with doctors. "You have to differentiate the salesperson in the customer's mind--just like you differentiate brands," he explains. A doctor may see 60 pharmaceutical reps on a regular basis but actually trust far fewer. To earn a spot in this inner circle, Schering-Plough reps try to turn each customer encounter into an occasion to help doctors provide better care for their patients. Schering-Plough also restructured its sales forces so that reps carry not just one kind of product, as they do in most pharmaceutical companies, but several. Covering a broad range of treatments gives reps more ways to build value-adding relationships with doctors. In this interview, Hassan discusses his success at Schering-Plough and his experiences at other pharmaceutical companies. During his career, he has built a reputation for being in tune with the front lines, as well as for reaching out to the managers who supervise salespeople. He has found that this level of personal attention not only makes reps feel respected but also gives him valuable strategic insights. PMID:16846192

  7. [Morphine by external route, prescribed to Heinrich Heine by David Gruby].

    PubMed

    Chast, F

    1998-01-01

    The exhibition held in Paris commemorating the bicentenial of Heinrich Heine showed three prescriptions by Dr. D. Gruby, through which morphine was prescribed for the poet by external route. The use of morphine was justified in a patient with unrelieved pain caused by neurosyphilis during the last twelve years of his life. This way of morphine administration (endemic method) was quite popular between 1830 and 1860. The process consisted in stripping the derm with the help of a vesicant and in applying directly on it morphine salts crystals. Several authors commented the interest of this way of administration rather uncomfortable for the patient but apparently very effective. PMID:11625475

  8. David Kirk on Physical Education and Sport Pedagogy: In Dialogue with Steven Stolz (Part 2)

    ERIC Educational Resources Information Center

    Stolz, Steven A.; Kirk, David

    2015-01-01

    Forming the second of two articles, this dialogue revisits and explores the educational value of physical education as a means to stimulate further discussion about what physical education is, or as Kirk states within this interview, what do "we want physical education to be". Although the theme of the second interview relates to the…

  9. Fabricius, David (1564-1617) and Fabricius, Johannes (1587-1616)

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    Lutheran pastor and astronomer in Osteel, East Frisia (northwest Germany), discoverer (1596) of the first known variable star, mira stella (`wonderful star'), now simply Mira (Omicron Ceti). Fabricius observed the star at its brightest and thought it was a nova, after which Holwarda noticed that a star in Cetus cataloged by PTOLEMY and TYCHO was missing but then it reappeared. Eventually the long...

  10. Four decades of discovery in breast cancer research and treatment--an interview with V. Craig Jordan. Interview by Marc Poirot.

    PubMed

    Jordan, V Craig

    2011-01-01

    V. Craig Jordan is a pioneer in the molecular pharmacology and therapeutics of breast cancer. As a teenager, he wanted to develop drugs to treat cancer, but at the time in the 1960s, this was unfashionable. Nevertheless, he saw an opportunity and through his mentors, trained himself to re-invent a failed "morning-after pill" to become tamoxifen, the gold standard for the treatment and prevention of breast cancer. It is estimated that at least a million women worldwide are alive today because of the clinical application of Jordan's laboratory research. Throughout his career, he has always looked at "the good, the bad and the ugly" of tamoxifen. He was the first to raise concerns about the possibility of tamoxifen increasing endometrial cancer. He described selective estrogen receptor modulation (SERM) and he was the first to describe both the bone protective effects and the breast chemopreventive effects of raloxifene. Raloxifene did not increase endometrial cancer and is now used to prevent breast cancer and osteoporosis.The scientific strategy he introduced of using long term therapy for treatment and prevention caused him to study acquired drug resistance to SERMs. He made the paradoxical discovery that physiological estrogen can be used to treat and to prevent breast cancer once exhaustive anti-hormone resistance develops. His philosophy for his four decades of discovery has been to use the conversation between the laboratory and the clinic to improve women's health.

  11. On-line prediction of yield grade, longissimus muscle area, preliminary yield grade, adjusted preliminary yield grade, and marbling score using the MARC beef carcass image analysis system.

    PubMed

    Shackelford, S D; Wheeler, T L; Koohmaraie, M

    2003-01-01

    The present experiment was conducted to evaluate the ability of the U.S. Meat Animal Research Center's beef carcass image analysis system to predict calculated yield grade, longissimus muscle area, preliminary yield grade, adjusted preliminary yield grade, and marbling score under commercial beef processing conditions. In two commercial beef-processing facilities, image analysis was conducted on 800 carcasses on the beef-grading chain immediately after the conventional USDA beef quality and yield grades were applied. Carcasses were blocked by plant and observed calculated yield grade. The carcasses were then separated, with 400 carcasses assigned to a calibration data set that was used to develop regression equations, and the remaining 400 carcasses assigned to a prediction data set used to validate the regression equations. Prediction equations, which included image analysis variables and hot carcass weight, accounted for 90, 88, 90, 88, and 76% of the variation in calculated yield grade, longissimus muscle area, preliminary yield grade, adjusted preliminary yield grade, and marbling score, respectively, in the prediction data set. In comparison, the official USDA yield grade as applied by online graders accounted for 73% of the variation in calculated yield grade. The technology described herein could be used by the beef industry to more accurately determine beef yield grades; however, this system does not provide an accurate enough prediction of marbling score to be used without USDA grader interaction for USDA quality grading.

  12. Helping American Soldiers in Time of War: Reply to Comments on the Comprehensive Soldier Fitness Special Issue

    ERIC Educational Resources Information Center

    Seligman, Martin E. P.

    2011-01-01

    Seligman responds to the comments made about the January 2011 "American Psychologist" "Special Issue on Comprehensive Soldier Fitness" (CSF). Seligman proposed an entire issue of on the topic of CSF to encourage psychologists to come to the aid of our government, and he urges psychologists not to be discouraged by this tactic. He and his coauthors…

  13. Nonverbal Communication and Response to Performance Feedback in Depression.

    ERIC Educational Resources Information Center

    Prkachin, Kenneth M.; And Others

    Recent theories of depression that have attracted enthusiasm are those of Lewinsohn and Seligman. Lewinsohn's theory emphasizes the importance of deficits in social skill leading to reduced reinforcement, while Seligman's emphasizes the evolution of the depressive's belief that his responding and reinforcement are independent. The present study…

  14. Positive Psychology versus the Medical Model?: Comment

    ERIC Educational Resources Information Center

    Joseph, Stephen; Linley, P. Alex

    2006-01-01

    Comments on "Positive psychology progress: Empirical validation of interventions" by Seligman, Steen, Park, and Peterson (see record 2005-08033-003). Seligman and colleagues provided a progress report on positive psychology, reviewing the impressive developments over the past five years. We wholeheartedly support the positive psychology movement…

  15. ISS Update: Russian Spacesuits and Spacewalks

    NASA Video Gallery

    NASA Public Affairs Officer Brandi Dean interviews Marc Ciupitu, EVA Flight and Increment Manager, about the Russian Orlan spacesuits that cosmonauts wear during spacewalks. Marc also discusses wha...

  16. Eponymous doctors associated with Edinburgh, Part 2--David Bruce, John Cheyne, William Stokes, Alexander Monro Secundus, Joseph Gamgee.

    PubMed

    Doyle, D

    2006-12-01

    This, the second in a three-paper series with this title, looks at famous doctors who trained in Edinburgh and their eponyms. With one possible exception, none seems to have sought the eponym, nor awarded it to themselves, nor used it for self-promotion. Unlike those in the first paper, all eponyms in this paper are still in use and their brevity is in contrast to the lengthy description needed if the eponym is not used. Examples are Cheyne-Stokes respiration, Stokes-Adam attacks, Brucellosis and Gamgee dressing. Monro Secundus is included because of his vehement defence of his professional reputation and research findings when he suspected others of trying to detract credit from him, a characteristic seldom reported for the others. PMID:17526135

  17. The 2007 ESPEN Sir David Cuthbertson Lecture: amino acids between and within organs. The glutamate-glutamine-citrulline-arginine pathway.

    PubMed

    Deutz, Nicolaas E P

    2008-06-01

    In daily practice, the plasma concentration of amino acids is usually viewed as a parameter of production. However, both a high production and/or a reduced disposal capacity can result in an increased plasma concentration. In this presentation, I will discuss my research on interorgan relationships of the amino acids glutamate, glutamine, citrulline and arginine to explain the regulation of the plasma arginine level. The reduced glutamine disposal during liver failure is related to enhanced plasma glutamine level without any change in muscle and gut production or consumption rate. In contrast during sepsis, a small reduction in plasma glutamine is related to a substantially enhanced organ glutamate and glutamine production or consumption rate. These observations are a good example that plasma levels are directly related to production or consumption rates. Because glutamine breakdown in the gut produces citrulline, there is a good relation between the amount of metabolically active gut tissue and gut and whole body citrulline production. Arginine is produces from citrulline in the kidney and a reduced gut glutamine to citrulline conversion during sepsis explains the reduced de novo arginine production that is related to the reduced plasma arginine level. The interorgan route between muscle, gut, liver and kidney of the amino acids glutamate, glutamine, citrulline and arginine is a very good example of how complicated the regulation of plasma amino acid levels can be. However, in-depth research is necessary and will give us important clues to new nutritional strategies.

  18. Business Culture and the Death of Public Education: Mayor Bloomberg, David Steiner, and the Politics of Corporate "Leadership"

    ERIC Educational Resources Information Center

    Giroux, Henry A.

    2011-01-01

    This article provides a case study of how a business culture imposes modes of educational leadership on a public school system in New York City that has little if any concerns for empowering children, teachers, and the communities. The article provides a counter-narrative that serves to dispel the notion that the culture of educational empowerment…

  19. Economic Efficiency and Equity in Dams Removal: Case studies in Northeastern Massachusetts Doina Oglavie, Ellen Douglas, David Terkla

    NASA Astrophysics Data System (ADS)

    Oglavie, D. R.; Douglas, E. M.; Terkla, D.

    2009-12-01

    According to American Rivers (www.americanrivers.org), Massachusetts has almost 3,000 dams under state regulation, 296 of which have been classified as high hazard, meaning they pose a serious threat to human life if they should fail. Most of these dams, however, are low head, “run-of-the-river” dams that no longer serve the purpose for which they were built. The presence of these dams has fragmented aquatic and riparian ecosystems, impeded fish passage and generally impacted the natural ecological and hydrological functioning of the streams in which they reside. Dam removal should be considered when a dam no longer serves its function. Although in many cases, the removal of a dam is environmentally beneficial (at least over the long term), sometimes the removal of a dam can incur environmental costs, such as release of contaminants that were sequestered behind the dam. Dam removal is a complex issue especially with respect to privately owned dams. In many cases, dam removal is less costly than dam maintenance or upgrade, hence dam removal decisions tend to be based on purely monetary considerations, and the environmental costs or benefits associated with the dam are not considered. Typically, the main objective for the dam owner is to incur the lowest possible cost (private cost), whether it be operating and maintenance or removal; external costs (environmental degradation) are rarely, if ever, considered, hence the true cost to society is not included in the economic analysis. If dam operation and removal decisions are to be economically efficient, then they have to include both the private costs as well as the external (environmental) costs. The purpose of this work is to 1) attempt to quantify the externalities associated with the maintenance and the removal of dams, 2) assess whether or not the current dam removal evaluation process maximizes social welfare (efficiency and equity) and 3) suggest ways in which this process can be improved by including the identified externalities. Economic efficiency occurs when the greatest total social value is obtained for the least possible social cost. Equity is related to the fair and just distribution of benefits and costs among individuals and society. Our first evaluation looked at the decisions made with respect to two dams situated on the Ipswich River in northeastern Massachusetts: Bostik Dam and EBSCO Dam. The Bostik Dam provides water storage for nearby industrial facilities. It is the third dam on the main stem of the Ipswich River and is the most downstream dam without provisions for fish passage. The EBSCO Dam is the most downstream dam on the Ipswich River and presently has no functional use. After several meetings between owners, residents, and agencies involved in the process, the final decision was to remove the Bostik Dam. However, our preliminary analysis indicated that it would be more economically efficient and equitable to remove the EBSCO Dam instead. The next step in our project will be refine our economical analysis of these dams and apply our methods to other dams slated for removal in northeastern Massachusetts.

  20. 76 FR 14388 - David Creasey; Notice of Application Tendered for Filing With the Commission, Accepted for Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... which would back up water in Lincoln Creek; (2) a 1,650-foot-long, 21-inch-diamter PVC penstock with an...) an approximately 75-foot-long, 12-inch-diamater PVC pipe which would return flows to the...