KUPSnet: Knowledge-based Ubiquitous and Persistent Sensor Network Testbed for Threat Assessment

DTIC Science & Technology

2010-09-16

P. Sawant, M.S. Thesis, Wireless Sensor Network Testbed: Measurement and Analysis, August 2007. 2.3 Current Ph.D Students With two new PhD students...Students With two new MS students (Sana Agaskar and Ankit Agarwal) joining us in August 2010, we have seven M.S. students in this group. 1. Ashith...2010. [2] Qilian Liang, Xiuzhen Cheng, Sherwood Samn, “ NEW : Network-enabled Electronic Warfare for Target Recognition,” IEEE Trans on Aerospace and

Energy-Efficient High-Performance Routers

DTIC Science & Technology

2012-02-01

award, the PI Dr. Sartaj Sahni, AFRL research scientist Dr. Gunasekaran Seetharaman, and University of Florida Ph.D. student Ms. Tania Banerjee...Sartaj Sahni, AFRL research scientist Dr. Gunasekaran Seetharaman, and University of Florida Ph.D. student Ms. Tania Banerjee-Mishra...Searching and Shift Redundancy Architecture, IJSSC, 40, 1, Jan 2005, 245-253. PC-DUOS+: A TCAM Architecture for Packet Classifiers Tania Banerjee

MS PHD'S: Bridging the Gap of Academic and Career Success Through Educational and Professional Development for Minorities

NASA Astrophysics Data System (ADS)

Brown, D.; Vargas, W.; Padilla, E.; Strickland, J.; Echols, E.; Johnson, A.; Williamson Whitney, V.; Ithier-Guzman, W.; Ricciardi, L.; Johnson, A.; Braxton, L.

2011-12-01

Historically, there has been a lack of ethnic and gender diversity in the geo-sciences. The Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science (MS PHD'S) Professional Development Program provides a bridge to young scientists of diverse backgrounds who in turn will impact many. In a process of 3 phases, the program introduces the students to the scientific community through participation in professional and society meetings and networking with scientists and personnel within federal agencies, academic institutions and STEM-based industries. The program builds confidence, offers role models for professional development and provides students support during their education. Upon completion, students achieve a high level of self-actualization and self-esteem combined with individual growth. They become part of a community that continuously provides support and security to each other. This support is tangible through the mentor/mentee relationships which will help with individual growth throughout the mentoring cycle. Having role models and familiar faces to whom mentees can relate to will encourage our students to succeed in the STEM's field. To date, 159 students have participated in the program: 26 have successfully completed their PhD and 56 are currently enrolled in the PhD programs nationwide. The MS PHD'S Program creates a forum of diverse peoples by diverse peoples with diverse interest and strength, where the ongoing goal is to continually raise the bar for each individual. MS PHD'S establishes a nurturing goal-oriented environment for the geo scientist of the future who in turn will make profound contributions on a local, national and global scale. To conclude, MSPHD'S not only bridges the gap of unrepresented minorities in STEM careers, but also generates educational approaches to make the earth system sciences available to more, impacting all.

Unclassified Publications of Lincoln Laboratory 1 January - 31 December 1994, Volume 20.

DTIC Science & Technology

1994-12-31

J. Ehrlich, DJ. Hollis, M.A. Kosicki, B.B. Powdrill, T. Beattie, K. Smith, S. Varma, R. Gangadharan, R. Mallik , A. Burke, B.E. Wallace, D...JA-6972, JA-7028 Mallik , A., JA-7164 Manfra, M.J., JA-7027, MS-10604 Mankiewich, P.M., JA-7001 Maragos, P., JA-6764, JA-6888 Marcus, S., JA-6898

MS PHD'S: A successful model for reaching underrepresented minorities (URM) students through virtual platforms

NASA Astrophysics Data System (ADS)

Scott, O.; Johnson, A.; Williamson, V.; Ricciardi, L.; Jearld, A., Jr.; Guzman, W. I.

2014-12-01

To successfully recruit and retain underrepresented minority (URM) students and early career scientists, many programs supplement traditional curricular activities with multiple online platforms, establishing "virtual communities" that are free and easily accessible. These virtual communities offer readily sustainable opportunities to facilitate communication across a wide range of cultural lines and socioeconomic levels thereby broadening participation and inclusivity in STEM. Established in 2003, the Minorities Striving and Pursuing Higher Degrees of Success (MS PHD'S) in Earth System Science Professional Development Program has successfully used virtual community tools such as a listserv, community forum, social media, and VoIP technologies, to extend the face-to-face activities of the program and support the advancement of URM students and early career scientists in STEM. The use of multiple facets of virtual community by MS PHD'S participants supports and encourages "real life" interactions and mentorship, facilitates networking and professional development, and maintains continuity of shared networks. The program is now in its ninth cohort and supports 213 participants. To date, 54 participants have completed their PhD and another 61 are currently enrolled in doctoral programs.

Marcus Theory of Ion-Pairing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roy, Santanu; Baer, Marcel D.; Mundy, Christopher J.

We present a theory for ion pair dissociation and association, motivated by the concepts of the Marcus theory of electron transfer. Despite the extensive research on ion-pairing in many chemical and biological processes, much can be learned from the exploration of collective reaction coordinates. To this end, we explore two reaction coordinates, ion pair distance and coordination number. The study of the correlation between these reaction coordinates provides a new insight into the mechanism and kinetics of ion pair dissociation and association in water. The potential of mean force on these 2D-surfaces computed from molecular dynamics simulations of different monovalentmore » ion pairs reveal a Marcus-like mechanism for ion-pairing: Water molecules rearrange forming an activated coordination state prior to ion pair dissociation or association, followed by relaxation of the coordination state due to further water rearrangement. Like Marcus theory, we find the existence of an inverted region where the transition rates are slower with increasing exergonicity. This study provides a new perspective for the future investigations of ion-pairing and transport. SR, CJM, and GKS were supported by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences, and Biosciences. MDB was supported by MS3 (Materials Synthesis and Simulation Across Scales) Initiative, a Laboratory Directed Research and Development Program at Pacific Northwest National Laboratory (PNNL). The research was performed using PNNL Institutional Computing. PNNL is a multi-program national laboratory operated by Battelle for the U.S. Department of Energy.« less

Jochem Weber | NREL

Science.gov Websites

mechanical engineering (design) and physical engineering (fluid and system dynamics), and a Ph.D. in modeling Ph.D. in Engineering, University College Cork (Ireland); M.S. and B.S. in Physical Engineering

Expected Position Error for an Onboard Satellite GPS Receiver

DTIC Science & Technology

2015-03-01

Committee Membership: Dr. Alan Jennings, PhD Chairman Dr. Eric D. Swenson, Ph.D. Member Dr. Marshall E. Haker , Ph.D. Member AFIT-ENY-MS-15-M-029 Abstract...acknowledge both Dr. Jennings and Maj Haker for taking on the role of being my advisor and as well as committee member at various times during this

Fusion of Multiple Sensing Modalities for Machine Vision

DTIC Science & Technology

1994-05-31

Modeling of Non-Homogeneous 3-D Objects for Thermal and Visual Image Synthesis," Pattern Recognition, in press. U [11] Nair, Dinesh , and J. K. Aggarwal...20th AIPR Workshop: Computer Vision--Meeting the Challenges, McLean, Virginia, October 1991. Nair, Dinesh , and J. K. Aggarwal, "An Object Recognition...Computer Engineering August 1992 Sunil Gupta Ph.D. Student Mohan Kumar M.S. Student Sandeep Kumar M.S. Student Xavier Lebegue Ph.D., Computer

The Cultural Imperative for Professional Military Education and Leader Development

DTIC Science & Technology

2010-01-01

Institute for the Behavioral and Social Sciences. She previously was a visiting assistant professor at George Washington University. She holds bachelor...degrees in psychology and political science from the University of Southern Mississippi and an M.S. and Ph.D. in social and personality psychology from...Behavioral and Social Sciences. He has a B.S. in industrial and labor relations from Cornell University and an M.S. and Ph.D. in social psychology

Installation Restoration Program. Phase 2. Confirmation/Quantification Stage 1. US Air Force Plant Number 42, Palmdale, California. Volume 1

DTIC Science & Technology

1987-02-20

Bacteriology; 8 years professional experience; served as Project Health and Safety Officer. 1-37 o Duane R. Boline - Ph.D. in Analytical Chemistry ; M.S. in... Chemistry ; B.S.E. in Physical Science; 18 years professional experience; served as Project Quality Assurance Officer. Complete biographical data...University, 1962 M.S., Chemistry , Einporia State University 1965 Ph.D., Analytical Chemistry , Kansas State University, 1975

Combat Readiness Check (CRC): Development of a Dual Task Assessment Protocol to Assist with Return-to-Duty Decision-Making After Traumatic Brain Injury

DTIC Science & Technology

2010-10-01

injury CO-PRINCIPAL INVESTIGATORS: Mary Vining Radomski, PhD, OTR/L and Maggie Weightman, PT, PhD (Sister Kenny Research Center [SKRC]) CO...INVESTIGATORS: Leslie Davidson PhD (Cand), MS, OTR/L (Riverbend); MAJ Sarah Goldman PhD, OTR/L, CHT (United States Army Research Institute of Environmental...of Minnesota) ASSISTED BY: Dr. Kristin Heaton and Amanda Antczak (USARIEM) and Marsha Finkelstein (health services researcher ), Michelle Pose, and

Are MS in Economics Programs in Departments That Also Have a PhD Program in Economics Different from Their Counterparts?

ERIC Educational Resources Information Center

Milkman, Martin I.; Marjadi, Riza; McCoy, James P.

2016-01-01

This is the first article that compares terminal master's degree programs in economics from universities that have a PhD program in economics with those that do not offer PhD programs in economics. The authors compare these differences based on surveys in 2002 and 2012. They examine differences in general program characteristics, department…

Morphodynamics and Geology of the Southeastern Virginia Shelf: False Cape Shoals Area (Phase 2)

DTIC Science & Technology

2001-09-30

Code 322PO Randolph A. McBride, Ph.D. Assistant Professor of Geology Environmental Science and Policy, MS 5F2 George Mason University Fairfax...NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Environmental Science and Policy, MS 5F2,,George Mason...Geology Laboratory at George Mason University. In addition, a Ph.D. student in Environmental Science and Policy, who is working under the direction

Richard Mazurchuk, PhD | Division of Cancer Prevention

Cancer.gov

Dr. Richard Mazurchuk received a BS in Physics and MS and PhD in Biophysics from SUNY Buffalo. His research focused on developing novel multi-modality imaging techniques, contrast (enhancing) agents and methods to assess the efficacy of experimental therapeutics. |

76 FR 11961 - Safety Zone, Dredging Operations; Delaware River, Marcus Hook, PA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-04

...-AA00 Safety Zone, Dredging Operations; Delaware River, Marcus Hook, PA AGENCY: Coast Guard, DHS. ACTION... Delaware River while the Dredge Pullen conducts dredging operations at the Sunoco Marcus Hook docks in the vicinity of the Marcus Hook Range near Marcus Hook, PA. This action is necessary to maintain the 42 ft...

MYOCARDIAL INJURY FROM INHALED COMBUSTION PARTICLES: IS THERE A ROLE FOR ZINC?

EPA Science Inventory

Myocardial injury from inhaled combustion particles: Is there a role for zinc?
U.P.Kodavanti, PhD 1, C.F.Moyer, PhD, DVM 2, A.D.Ledbetter, BS 1, M.C.Schladweiler, BS
1, P.S.Gilmour, PhD 1, R.Hauser, ScD, MPH 3, D.C.Christiani, MPH, MS 3, D.L.Costa, ScD
1 and A.Ny...

Launching a Geoscience Career: Insights Gained from MS PHD'S Beyond the PhD

NASA Astrophysics Data System (ADS)

Guzman, W. I.; Johnson, A.; Williamson Whitney, V.; Jansma, P. E.; Huggans, M. J.; Ricciardi, L.

2013-05-01

The Beyond the PhD (B-PhD) Professional Development Program is the newest addition to the Minorities Striving and Pursuing Higher Degrees of Success (MS PHD'S®) Professional Development Program in Earth System Science. This exciting new program is designed to facilitate the development of a new community of underrepresented minority (URM) doctoral candidates and recent doctorate degree recipients in Earth system science (ESS)-related fields. Building upon MS PHD'S extensive professional development activities provided to URM undergraduate and graduate students, B-PhD's vision is to encourage and support URM doctoral students and early career PhD's in becoming part of the global workforce. (Since its inception in 2003, MSPHD'S supports 213 participants of which 42 have achieved the doctoral degree and another 71 are enrolled in doctoral programs.) By providing customized support and advocacy for participants, B-PhD facilitates smoother and informed transitions from graduate school to postdoctoral and tenure-track positions, as well as other "first" jobs in academia, government, industry, and non-profit organizations. In 2011, the first conference for 18 doctoral candidate and recent graduates was hosted at the University of Texas at Arlington's (UTA) College of Science. Using a format of guest speakers, brown bag discussions, and interactive breakout sessions, participants engaged in sessions entitled "Toolkits for Success in Academia, Business and Industry, Federal Government and Non-Profits", "Defining Short, Mid and Long Term Career Goals", "Accessing and Refining Skill Sets and Other Door Openers", "International Preparation and Opportunities", "Paying it Forward/Lifting as You Climb", and "Customized Strategies for Next Steps". This presentation will discuss outcomes from this pilot project, the use of social media to track and support ongoing B-PhD activities, and objectives for future B-PhD workshops.

Ambarish Nag | NREL

Science.gov Websites

|Mathematical biology Education Ph.D., Computational Chemistry, University of Chicago M.S., Chemistry , University of Chicago M.S., (2-Year) Chemistry, Indian Institute of Technology, Kanpur, India B.S., Chemistry

Sharpen your bargaining skills.

PubMed

Marcus, L J

1996-10-14

As the health-care revolution continues, bargaining skills have become more crucial for doctors than ever before. If you want your practice to thrive, you must regularly negotiate with colleagues, practice administrators, allied health professionals, managed-care plans, business groups, hospitals, and the government. Yet medical schools and residency programs devote little if any time to negotiating skills. The "golden days," when physicians could afford to be mavericks, are over. Doctors must develop a new collaborative outlook to be successful and happy in their careers, says Leonard J. Marcus, Ph.D., lead author of the book "Renegotiating Health Care: Resolving conflict to Build Collaboration." He and his co-authors often conduct seminars for health professionals on improving bargaining skills. The following excerpt concerns the role of conflict in negotiation, and how to resolve it.

Joint Services Electronics Program

DTIC Science & Technology

1990-07-31

Raghunath , Mandayam M.S. 88 Raman, Shankar M.S. 88 Scheckler, Ed M.S. 88 Song. Joon Ph. D. 88 Tsay, Jcnngang M.S. 89 Tsay, Rcn-Song Ph.D. 89 Vakhshoori...from Planar Resonators," submitted for publication to IEEE Trans. on Microwave Theory and Techniques, on April 17, 1990. Ranade M.T. Raghunath and A.G

Marcus equation

DOE R&D Accomplishments Database

1998-09-21

In the late 1950s to early 1960s Rudolph A. Marcus developed a theory for treating the rates of outer-sphere electron-transfer reactions. Outer-sphere reactions are reactions in which an electron is transferred from a donor to an acceptor without any chemical bonds being made or broken. (Electron-transfer reactions in which bonds are made or broken are referred to as inner-sphere reactions.) Marcus derived several very useful expressions, one of which has come to be known as the Marcus cross-relation or, more simply, as the Marcus equation. It is widely used for correlating and predicting electron-transfer rates. For his contributions to the understanding of electron-transfer reactions, Marcus received the 1992 Nobel Prize in Chemistry. This paper discusses the development and use of the Marcus equation. Topics include self-exchange reactions; net electron-transfer reactions; Marcus cross-relation; and proton, hydride, atom and group transfers.

Practical Recommendations for Trait-Level Estimation in the Navy Computer Adaptive Personality Scales (NCAPS)

DTIC Science & Technology

2010-11-30

www.nprst.navy.mil NPRST-TN-11-1 November 2010 Practical Recommendations for -level Estimation in NCAPS Frederick L. Oswald, Ph.D. Rice University...Navy Computer Adaptive Personality Scales ( NCAPS ) Frederick L. Oswald, Ph.D. Rice University Reviewed, Approved, and Released by David M...Personality Scales ( NCAPS ) Frederick P. Oswald, Ph.D. Rice University 6100 Main St., MS25 Houston, TX 77005 Navy Personnel Research, Studies, and

Segmental Neogenesis of the Dog Esophagus Utilizing a Biodegradable Polymer Framework

DTIC Science & Technology

1988-12-20

Dental (If applicable) US Army Medical Research & Development Research I SGRD-UDR-B Command (HQDA-IS) 6c. ADDRESS (City, State, and ZIP Code) 7b. ADDRESS...Marvin F. Grower, D.D.S., Ph.D. Emery A. Russell, Jr., D.D.S., M.S. Duane E. Cutright, D.D.S., M.S., Ph.D. U. S. Army Institute of Dental Research...the polymer solutions with a #152 dental atomizer (DeVilbiss Corp.) using 20-30 psi of nitrogen as a prdpellant at a distance of 10-18 inches from a

Paul W. King, Ph.D., M.S. | NREL

Science.gov Websites

converting solar energy into biofuels. Specific areas of interest include using molecular, biochemical and Photochemical Conversion Photobiological Hydrogen Production Education Ph.D., Biochemistry and Molecular Biology , Mechanism, and Maturation," Biochimica et Biophysica Acta-Molecular Cell Research (2015) need_alt "

INFLUENCE OF DIETARY ARSENIC ON URINARY ARSENIC METABOLITE EXCRETION

EPA Science Inventory

Influence of Dietary Arsenic on Urinary Arsenic Metabolite Excretion

Cara L. Carty, M.S., Edward E. Hudgens, B.Sc., Rebecca L. Calderon, Ph.D., M.S.P.H., Richard Kwok, M.S.P.H., Epidemiology and Biomarkers Branch/HSD, NHEERL/US EPA; David J. Thomas, Ph.D., Pharmacokinetics...

Pathways to URM Retention: IBP's Professional Development and Mentoring Activities

NASA Astrophysics Data System (ADS)

Johnson, A.; Williamson Whitney, V.; Ricciardi, L.; Detrick, L.; Siegfried, D.; Fauver, A.; Ithier-Guzman, W.; Thomas, S. H.; Valaitis, S.

2013-05-01

As a not for profit organization, the Institute for Broadening Participation (IBP) hosts a variety of initiatives designed to increase the retention of underrepresented minority (URM) students pursuing pathways in STEM. IBP also assists with formative program evaluation design and implementation to help strengthen URM recruitment and retention elements. Successful initiatives include virtual and face-to-face components that bring together URM students with established URM and other scientists in academia, government and industry. These connections provide URMs with mentoring, networking opportunities, and professional skill development contributing to an improved retention rate of URM students. IBP's initiatives include the NASA One Stop Shopping Initiative (NASA OSSI), Pathways to Ocean Science and Engineering, and the Minorities Striving and Pursuing Higher Degrees of Success (MS PHD'S) in Earth System Science (ESS) Professional Development Program. The NASA OSSI recruits and facilitates student engagement in NASA education and employment opportunities. Pathways to Ocean Science connects and supports URM students with Ocean Science REU programs and serves as a resource for REU program directors. Pathways to Engineering has synthesized mentoring resources into an online mentoring manual for URM students that has been extensively vetted by mentoring experts throughout the country. The mentoring manual, which is organized by roles, provides undergraduates, graduates, postdocs, faculty and project directors with valuable resources. MS PHD'S, one of IBP's longest running and most successful initiatives, focuses on increasing the retention rate of URM students receiving advanced degrees in ESS. The program addresses barriers to retention in ESS including isolation, lack of preparation and professional development, and lack of mentoring. Program activities center on peer-to-peer community building, professional development exercises, networking experiences, one-on-one mentoring, and a facilitated virtual community. MS PHD'S students report a reduced sense of isolation, an increased sense of community, and a higher level of confidence about their ability to succeed in their chosen field. 42 MS PHD'S alumni have completed their PhD and are actively engaged in the ESS workforce.

Praxis Exiled: Herbert Marcuse and the One Dimensional University

ERIC Educational Resources Information Center

Cunningham, Joseph

2013-01-01

Leading Frankfurt School theorist, Herbert Marcuse, possessed an intricate relationship with higher education. As a professor, Marcuse participated in the 1960s student movements, believing that college students had potential as revolutionary subjects. Additionally, Marcuse advocated for a college education empowered by a form of praxis that…

Transactions of the Army Conference on Applied Mathematics and Computing (8th) Held in Ithaca, New York on 19-22 June 1990

DTIC Science & Technology

1991-02-01

Shamos, M I , "Computational Geometry", Ph.D Thesis , Department of Computer Science, Yale University, New Haven CT, 1978. [53] Steiglitz, K., An...431) whose real and imaginary parts are given by 222 mj cos OmJ + Az -mL cos 2 ML + MS Cos 2MS (432) mj sinO 0M cose OM = L sin aML cos ML + m S sin 9...Aequationes Math. 14, 1976, 271-291. 5. Greenwell, C.E., Finite element methods for partial integro-differential equations, Ph.D. Thesis , University of

Effect of nickel silicide gettering on metal-induced crystallized polycrystalline-silicon thin-film transistors

NASA Astrophysics Data System (ADS)

Kim, Hyung Yoon; Seok, Ki Hwan; Chae, Hee Jae; Lee, Sol Kyu; Lee, Yong Hee; Joo, Seung Ki

2017-06-01

Low-temperature polycrystalline-silicon (poly-Si) thin-film transistors (TFTs) fabricated via metal-induced crystallization (MIC) are attractive candidates for use in active-matrix flat-panel displays. However, these exhibit a large leakage current due to the nickel silicide being trapped at the grain boundaries of the poly-Si. We reduced the leakage current of the MIC poly-Si TFTs by developing a gettering method to remove the Ni impurities using a Si getter layer and natively-formed SiO2 as the etch stop interlayer. The Ni trap state density (Nt) in the MIC poly-Si film decreased after the Ni silicide gettering, and as a result, the leakage current of the MIC poly-Si TFTs decreased. Furthermore, the leakage current of MIC poly-Si TFTs gradually decreased with additional gettering. To explain the gettering effect on MIC poly-Si TFTs, we suggest an appropriate model. He received the B.S. degree in School of Advanced Materials Engineering from Kookmin University, Seoul, South Korea in 2012, and the M.S. degree in Department of Materials Science and Engineering from Seoul National University, Seoul, South Korea in 2014. He is currently pursuing the Ph.D. degree with the Department of Materials Science and Engineering, Seoul National University, Seoul. He is involved in semiconductor device fabrication technology and top-gate polycrystalline-silicon thin-film transistors. He received the M.S. degree in innovation technology from Ecol Polytechnique, Palaiseau, France in 2013. He is currently pursuing the Ph.D. degree with the Department of Materials Science and Engineering, Seoul National University, Seoul. He is involved in semiconductor device fabrication technology and bottom-gate polycrystalline-silicon thin-film transistors. He is currently pursuing the integrated M.S and Ph.D course with the Department of Materials Science and Engineering, Seoul National University, Seoul. He is involved in semiconductor device fabrication technology and copper-gate polycrystalline-silicon thin-film transistors. He is currently pursuing the integrated M.S and Ph.D course with the Department of Materials Science and Engineering, Seoul National University, Seoul. He is involved in semiconductor device fabrication technology and bottom-gate polycrystalline-silicon thin-film transistors. He is currently pursuing the integrated M.S and Ph.D course with the Department of Materials Science and Engineering, Seoul National University, Seoul. He is involved in semiconductor device fabrication technology and bottom-gate polycrystalline-silicon thin-film transistors. He received the B.S. degree in metallurgical engineering from Seoul National University, Seoul, South Korea, in 1974, and the M.S. and Ph.D. degrees in material science and engineering from Stanford University, Stanford, CA, USA, in 1980 and 1983, respectively. He is currently a Professor with the Department of Materials Science and Engineering, Seoul National University, Seoul.

Rescuing Our Warriors from Chronic Pain: A Battlefield-to-Nondeployment Means to Prevent Opioid-induced Amplification of Neuropathic Pain from Traumatic Injury

DTIC Science & Technology

2017-10-01

Amplification of Neuropathic Pain from Traumatic Injury PRINCIPAL INVESTIGATOR: Linda R. Watkins , Ph.D. CONTRACTING ORGANIZATION: Regents of the...0161 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Linda R Watkins , Ph.D. Peter M Grace, Ph.D. Suzanne M Fulgham, M.S. 5d. PROJECT NUMBER 5e. TASK...but from their action on glia cells by binding to the TLR4 receptor ( Watkins , Hutchinson, Rice, Maier, Trends Pharmacol Sci., 2009). Opioid

The study of possible influences of licit and illicit drugs on driver behavior

DOT National Transportation Integrated Search

1971-12-01

Study authors were S. William Berg, M.D., John T. Fryback, A.B.; Donald M. Goldenbaum, Ph.D.; Ralph K. Jones, B.S.; Kent B. Joscelyn, J.D.; Roger P. Maickel, Ph.D.; William Z. Potter, M.D.; and Joseph Zabik, M.S. The study investigated the relationsh...

Management of Suicide-Related Events during Deployment

DTIC Science & Technology

2015-02-01

the supervision of the site PI, Dr. Barbara Stanley. Ms. Emily Biggs , a Master’s level Research assistant, left her position to attend graduate...study progress. The members of the Expert Panel are Lanny Berman, Ph.D., ABPP; Stephen V. Bowles, Ph.D., ABPP; John Bradley, M.D.; Russell B. Carr, M.D

Delaware Consortium for Undergraduate Minority Training in Prostate Cancer

DTIC Science & Technology

2008-02-01

Nanoparticle Hyperthermia Induced Wound-Healing Assay in Prostate Cancer Cells. Adaire T. Heady, Michael J. Bonder, Ph.D., David J. DeGraff, M.S., Robert...6 Development of Magnetic Nanoparticle Hyperthermia ...George C. Hadjipanayis, Ph.D., Delaware State University, Dover, DE, USA, University of Delaware, Neware, DE, USA The use of magnetic nanoparticle

Optical and Electronic Transport Properties of Luminescent Semiconductors, Amorphous Materials and Metastable Solids.

DTIC Science & Technology

1979-02-26

Williams, Electronic States of Semiconductors with Graded Periodic Inhomogeneities, Phys. Rev. Eli, 2200 (1975) . 7. P. DiBona and R. Ewing, ESR of...Fellow) - K. Daghir, Ph.D. (1974) (IBM) P. DiBona , M.S. (1967), Ph.D. (1974) (U.S. Navy, Surface Weapons Research Laboratory) D. Hoover (current

NASA Multidisciplinary Design and Analysis Fellowship Program

NASA Technical Reports Server (NTRS)

Schrage, D. P.; Craig, J. I.; Mavris, D. N.; Hale, M. A.; DeLaurentis, D.

1999-01-01

This report summarizes the results of a multi-year training grant for the development and implementation of a Multidisciplinary Design and Analysis (MDA) Fellowship Program at Georgia Tech. The Program funded the creation of graduate MS and PhD degree programs in aerospace systems design, analysis and integration. It also provided prestigious Fellowships with associated Industry Internships for outstanding engineering students. The graduate program has become the foundation for a vigorous and productive research effort and has produced: 20 MS degrees, 7 Ph.D. degrees, and has contributed to 9 ongoing Ph.D. students. The results of the research are documented in 32 publications (23 of which are included on a companion CDROM) and 4 annual student design reports (included on a companion CDROM). The legacy of this critical funding is the Center for Aerospace Systems Analysis at Georgia Tech which is continuing the graduate program, the research, and the industry internships established by this grant.

MS PHD'S PDP: Vision, Design, Implementation, and Outcomes of a Minority-Focused Earth System Sciences Program

NASA Astrophysics Data System (ADS)

Habtes, S. Y.; Mayo, M.; Ithier-Guzman, W.; Pyrtle, A. J.; Williamson Whitney, V.

2007-05-01

As minorities are predicted to comprise at least 33% of the US population by the year 2010, their representation in the STEM fields, including the ocean sciences, is still poorly established. In order to advance the goal of better decision making, the Ocean Sciences community must achieve greater levels of diversity in membership. To achieve this objective of greater diversity in the sciences, the Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science® Professional Development Program (MS PHD'S PDP), which was launched in 2003, is supported via grants from NASA's Office of Earth Science, and NSF's Directorate for Geosciences. The MS PHD'S PDP is designed to provide professional and mentoring experiences that facilitate the advancement of minorities committed to achieving outstanding Earth System Science careers. The MS PHD'S PDP is structured in three phases, connected by engagement in a virtual community, continuous peer and mentor to mentee interactions, and the professional support necessary for ensuring the educational success of the student participants. Since the pilot program in 2003, the MSPHD'S PDP, housed at the University of South Florida's College of Marine Science, has produced 4 cohorts of students. Seventy-five have completed the program; of those 6 have earned their doctoral degrees. Of the 45 current participants 10 are graduate students in Marine Science and 15 are still undergraduates, the remaining 10 participants are graduate students in other STEM fields. Since the implementation of the MSPHD'S PDP a total of 87 students and 33 scientist mentors have become part of the MSPHD'S virtual community, helping to improve the learning environment for current and future participants as well as build a community of minority students that encourages each other to pursue their academic degrees.

MS PHD'S: A Successful Model Promoting Inclusion, Preparation and Engagement of Underrepresented Minorities within the Geosciences Workforce

NASA Astrophysics Data System (ADS)

Padilla, E.; Scott, O.; Strickland, J. T.; Ricciardi, L.; Guzman, W. I.; Braxton, L.; Williamson, V.; Johnson, A.

2015-12-01

According to 2014 findings of the National Research Council, geoscience and related industries indicate an anticipated 48,000 blue-collar, scientific, and managerial positions to be filled by underrepresented minority (URM) workers in the next 15 years. An Information Handling Services (IHS) report prepared for the American Petroleum Institute forecasts even greater numbers estimating upward of 408,000 opportunities for URM workers related to growth in accelerated development of oil, gas and petroleum industries. However, many URM students lack the training in both the hard sciences and craft skills necessary to fill these positions. The Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science (MS PHD'S) Professional Development Program uses integrative and holistic strategies to better prepare URM students for entry into all levels of the geoscience workforce. Through a three-phase program of mentoring, community building, networking and professional development activities, MS PHD'S promotes collaboration, critical thinking, and soft skills development for participants. Program activities expose URM students to education, training and real-life geoscience workforce experiences while maintaining a continuity of supportive mentoring and training networks via an active virtual community. MS PHD'S participants report increased self-confidence and self-efficacy in pursuing geoscience workforce goals. To date, the program supports 223 participants of who 57, 21 and 16 have received Doctorate, Masters and Baccalaureate degrees respectively and are currently employed within the geoscience and related industries workforce. The remaining 129 participants are enrolled in undergraduate and graduate programs throughout the U.S. Geographic representation of participants includes 35 states, the District of Columbia, Puerto Rico and two international postdoctoral appointments - one in Saudi Arabia and the other in France.

MS PHD'S: Effective Pathways to Mentoring for Increasing Diversity in the Geoscience Workforce - What have we done? What can we still do?

NASA Astrophysics Data System (ADS)

Ricciardi, L.; Johnson, A.; Williamson Whitney, V.; Ithier-Guzman, W.; Johnson, A.; Braxton, L.

2011-12-01

In 2003 a young, African-American geoscientist and professor discovered significant gaps in the recruitment and retention of minority students within the post-secondary educational community and a subsequent correlation of underrepresentation within the geosciences workforce. From this research, a unique concept was born: The Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science Professional Development Program (MS PHD'S PDP). This program was founded upon a vision that minorities can and should play a role in facilitating a network to attract, retain and increase minority representation in the geosciences workforce. In 2003, the pilot MS PHD'S program focused on a simple grass roots concept of effective mentoring and professional development administered by and for minorities through professional development activities. Today the program has grown to an impressive number of alumni who, in addition to establishing careers in the ESS professional workforce, also return to mentor the next generation of upcoming minority geoscientists. Alumni, mentors and current participants not only experience what has grown into a three-phase program but also enjoy enhanced benefits of ongoing interaction through social media, list-servs and webinars. While keeping its feet firmly planted in its grass-roots philosophy of effective mentoring and professional development by and for minorities, the MS PHD'S program looks to the future, by asking the question, "What can we do next to ensure the future of maintaining and growing diverse representation in the geosciences workforce?" Looking ahead, future goals for the program include increasing its pilot representation motto of "by and for minorities", exploring new technologies and digital tools, and expanding its supportive network of distinguished academicians, scientific organizations, industry partners, alumni, peers, and representatives of non-science disciplines.

Katherine Hurst | NREL

Science.gov Websites

, followed by the completion of a M.S. in Chemical Engineering from the Colorado School of Mines. She received her Ph.D. in Chemical Engineering. Her thesis, which was performed at NREL under the direction of 2001-2005 Ph.D. Chemical Engineering, Colorado School of Mines, Golden, CO Research Fellowship at the

Taxonomic review of the family Discodorididae (Mollusca: Gastropoda: Nudibranchia) from Brazil, with descriptions of two new species.

PubMed

Alvim, Juliana; Pimenta, Alexandre Dias

2013-12-04

The family Discodorididae was previously represented by 11 species in Brazil; however, recently collected specimens from several localities in Rio de Janeiro, in addition to the study of material previously deposited in scientific collections, revealed the existence of 13 taxa: Diaulula greeleyi (MacFarland, 1909), Discodoris hummelincki (Ev. Marcus & Er. Marcus, 1963) comb. nov., Discodoris branneri MacFarland, 1909, Geitodoris pusae (Er. Marcus, 1955), Hoplodoris hansrosaorum Domínguez, García & Troncoso, 2006, Jorunna spazzola Er. Marcus, 1955, Jorunna spongiosa sp. nov., Paradoris mulciber (Ev. Marcus, 1971), Platydoris angustipes (Mörch, 1863), Rostanga byga Er. Marcus, 1958a, Taringa telopia Er. Marcus, 1955, Taringa iemanja sp. nov., and Thordisa diuda Er. Marcus, 1955. Discodoris voniheringi MacFarland, 1909 was previously regarded as nomen dubium, and this view is maintained in the present study. Three new records for the Brazilian coast are recognized among these 13 taxa; the previous record of Diaulula phoca (Ev. Marcus & Er. Marcus, 1967a) is rectified as Discodoris hummelincki comb. nov., constituting the first record of this species from Brazil; two new species, Taringa iemanja sp. nov. and Jorunna spongiosa sp. nov., are described in anatomical detail. The following taxa, which were formerly considered junior synonyms of species studied in this work, have been revalidated: Diaulula nayarita (Ortea & Llera, 1981), from the Pacific coast of Costa Rica, which differs from Diaulula greeleyi in the length and width of caryophyllidia; Discodoris mortenseni Ev. Marcus & Er. Marcus, 1963, from the Caribbean, which is likely to belong to Jorunna, yet differs from Jorunna spazzola in body size and coloration, radula appearance, and number of lamellae in the rhinophores; Jorunna luisae Ev. Marcus, 1976, which differs from Jorunna spazzola in the reproductive system, mainly in the size and shape of the accessory gland; and Thordisa azmani Cervera & García-Gómez, 1989, which differs from Thordisa diuda in the presence of two accessory glands in the genital atrium and the absence of one denticle in the external surface of the inner lateral teeth. Finally, the specimens of Geitodoris pusae reported from the European coast and Mediterranean Sea show differences in general coloration and in the radula, gill, and reproductive system, thereby these specimens likely refer to different taxa.

California State University Long Beach: Model for a Terminal Master's Program as a Bridge to PhD

NASA Astrophysics Data System (ADS)

Bill, Andreas; Kenealy, Patrick; Kwon, Chuhee; Papp, Zoltan; Pickett, Galen T.

The department of Physics & Astronomy at California State University Long Beach has redesigned its Master's program in 2008 with the goal to provide a true graduate experience in Physics. The hallmarks of the program are five core graduate courses and a research-based MS thesis. During the last five years, 42% of MS recipients (24 students) were accepted to PhD programs, 41% started private-sector STEM careers, and 17% decided on teaching and other paths. The program doubled in size during that period. In 2013 we also became one of six Bridge Sites and only non-PhD granting institution of the American Physical Society (APS). We will describe the structure of the MS program, its goals and its place in the University degree plan landscape. We will also discuss how the APS Bridge Program has been implemented in our institution and has influenced our MS program. We gratefully acknowledge support from a variety of sources that contributed to establish the MS program, including the APS Bridge Program, individual NSF and Army Research Laboratory Grants.

Transition from direct to inverted charge transport Marcus regions in molecular junctions via molecular orbital gating

NASA Astrophysics Data System (ADS)

Yuan, Li; Wang, Lejia; Garrigues, Alvar R.; Jiang, Li; Annadata, Harshini Venkata; Anguera Antonana, Marta; Barco, Enrique; Nijhuis, Christian A.

2018-04-01

Solid-state molecular tunnel junctions are often assumed to operate in the Landauer regime, which describes essentially activationless coherent tunnelling processes. In solution, on the other hand, charge transfer is described by Marcus theory, which accounts for thermally activated processes. In practice, however, thermally activated transport phenomena are frequently observed also in solid-state molecular junctions but remain poorly understood. Here, we show experimentally the transition from the Marcus to the inverted Marcus region in a solid-state molecular tunnel junction by means of intra-molecular orbital gating that can be tuned via the chemical structure of the molecule and applied bias. In the inverted Marcus region, charge transport is incoherent, yet virtually independent of temperature. Our experimental results fit well to a theoretical model that combines Landauer and Marcus theories and may have implications for the interpretation of temperature-dependent charge transport measurements in molecular junctions.

Effectiveness of Acupressure Treatment for Pain Management and Fatigue Relief in Gulf War Veterans

DTIC Science & Technology

2013-10-01

measures. II. KEYWORDS Acupressure, Reiki , Gulf War Illness, fatigue, chronic headache, musculoskeletal pain, electroencephalography, non-invasive...Consultant) Ernie Betz (Consultant – Reiki ) Wenning Zhao (Consultant) Yin Fang PhD (Consultant) Vlodek Siemionow PhD (Consultant) Due to...Zhao and Ms. Alice Langholt were recruited to provide the Acupressure and Reiki interventions. Dr. Juliet Hou was recruited as a medical monitor

PAIRED-CITY STUDY TO DETERMINE THE CONTRIBUTION OF SOURCE WATER TYPE TO THE ENDEMIC LEVEL OF MICROBIAL DISEASE

EPA Science Inventory

Paired-City Study to Determine the Contribution of Source Water Type to the Endemic Level of Microbial Disease

F Frost PhD, T Kunde MPH, L Harter PhD, T Muller MS, GF Craun PE MPH, RL Calderon MPH PhD

ABSTRACT

Context: The effectiveness of current drinking...

Modeling the Acoustic Channel for Simulation Studies

DTIC Science & Technology

2012-09-30

Michele Zorzi (PI), Prof. Gianfranco Pierobon (co-PI), Dr. Paolo Casari (post-doctoral researchers ) and Dr. Beatrice Tomasi (PhD student until 12/31...2011 and then post-doctoral researcher ), Mr. Daniele Munaretto (PhD student ), Mr. Giovanni Toso (engineer) and Mr. Matteo Lazzarin (MS student ...approach, are reported in [TWC2012]. DISSEMINATION ACTIVITIES The results obtained in the conducted reseach have been disseminated to the research

System-of-Systems Test Planning in a Complex Joint Environment

DTIC Science & Technology

2007-06-01

Marcus Aurelius Marcus Aurelius , Emperor of the Roman Empire from 161-180 A.D., was considered one of the great Stoic philosophers.30 The Stoic...number of experimental runs. 30 For more on Marcus Arelius and Stoic philosophy see http

Herbert Marcuse, Grandfather of the New Left.

ERIC Educational Resources Information Center

Bourne, Tom

1979-01-01

A little over ten years ago, Herbert Marcuse found himself in the cross fire of the student movement. The radical right saw in Marcuse an incitement to revolutionary action, but individualism distinguished him from doctrinaire Marxists. He upheld the importance of pure contemplation and theory. (MLW)

MS PHD'S Professional Development Program: A Scientific Renaissance in Cyberspace

NASA Astrophysics Data System (ADS)

Powell, J. M.; Williamson, V. A.; Griess, C. A.; Pyrtle, A. J.

2004-12-01

This study is a component of a four-year investigation of MS PHD'S Professional Development Program's virtual community through the lenses of underrepresented minority students in Earth system science and engineering fields. In this presentation, the development, assessment and projected utilization of the ongoing study will be discussed. The overall goal of this study is to examine the effectiveness of virtual team building methods and understand how the development of a communal cyberinfrastructure acts as an integral part of the emergence of a Scientific Renaissance. The exemplar, Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science (MS PHD'S), provides professional development experiences to facilitate the advancement of students of color achieving outstanding Earth system careers. Undergraduate and graduate students are supported through access to scientific conferences, mentorship and virtual community building. Framed by critical theory, this ethnographic exploration uses a mixed methods research design to record, observe, and analyze both the processes and products of the website, listserv and synchronous web-based dialogue. First, key findings of the formative evaluation and annual reports of the successfully implemented 2003 MS PHD'S Pilot Project are presented. These findings inform future evaluations of the use of technological resources and illustrate how this public space provides peer support and enriched research opportunities. Quantitative methods such as statistical analysis, academic and professional tracking and evaluative tools for scientific content and competency are complimented by qualitative methods that include observations, heuristic case studies and focus group interviews. The findings of this ongoing investigation will provide insight on how national organizations, higher education practitioners, community-based support systems and underrepresented minorities in the sciences promote diversity by developing successful cyberspace programs and networks. Through the examination of the transformation, expansion and democratization of the Earth system science community, new knowledge will be obtained on how a cyber-community fuses science, diversity and technology to form dialectics between creating and analyzing a Scientific Renaissance.

Fabrication of brittle materials -- current status

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scattergood, R.O.

The research initiatives in the area of precision fabrication will be continued in the upcoming year. Three students, T. Bifano (PhD), P. Blake (PhD) and E. Smith (MS), finished their research programs in the last year. Sections 13 and 14 will summarize the essential results from the work of the Materials Engineering students Blake and Smith. Further details will be presented in forthcoming publications that are now in preparation. The results from Bifano`s thesis have been published in adequate detail and need not be summarized further. Three new students, S. Blackley (MS), H. Paul (PhD), and S. Smith (PhD) havemore » joined the program and will continue the research efforts in precision fabrication. The programs for these students will be outlined in Sections 15 and 16. Because of the success of the earlier work in establishing new process models and experimental techniques for the study of diamond turning and diamond grinding, the new programs will, in part, build upon the earlier work. This is especially true for investigations concerned with brittle materials. The basic understanding of material response of nominally brittle materials during machining or grinding operations remains as a challenge. The precision fabrication of brittle materials will continue as an area of emphasis for the Precision Engineering Center.« less

Herbert Marcuse's Critical Theory of the Media.

ERIC Educational Resources Information Center

Daley, Patrick J.

As a member of the Frankfurt School of critical theory, Herbert Marcuse believed that industrial capitalism and the bureaucratization of society stripped humans of any claims to autonomy and undermined their critical expression with a functional language. However, Marcuse did no more than point an inchoate ideological finger at the production side…

The Operations Targeting and Effects Synchronization Process in Northern Iraq

DTIC Science & Technology

2010-06-01

deployment. _____________ IMAGE: Coin of Marcus Aurelius . The secret of all victory lies in the organization of the non-obvious. — Marcus Aurelius , 121-180...CE IN THE EARLY 4th century BCE, more than five centuries before the great philosopher-emperor Marcus Aurelius made the observation quoted above

Optimal Cost Avoidance Investment and Pricing Strategies for Performance-Based Post-Production Service Contracts

DTIC Science & Technology

2011-04-30

a BS degree in Mathematics and an MS degree in Statistics and Financial and Actuarial Mathematics from Kiev National Taras Shevchenko University...degrees from Rutgers University in Industrial Engineering (PhD and MS) and Statistics (MS) and from Universidad Nacional Autonoma de Mexico in Actuarial ...Science. His research efforts focus on developing mathematical models for the analysis, computation, and optimization of system performance with

The Effects of Continuous One-Arm Kettlebell Swing Training on Physiological Parameters in United States Air Force Personnel: A Pilot Study

DTIC Science & Technology

2016-11-01

collegiate soccer players . KB snatches were performed 3 days per week for 20 minutes with 15-second work-to-rest intervals, while the control group...10] used KB weights that were 18% of total body mass and reported a 6% improvement in aerobic capacity in women’s collegiate soccer players who...Force Personnel: A Pilot Study Molly Wade, MS; Reginald O’Hara, PhD; Lydia Caldwell, MS; Jason Ordway, MS; Darryn Bryant, MS

Finding Educational Insights in Psychoanalytic Theory with Marcuse and Adorno

ERIC Educational Resources Information Center

Huhtala, Hanna-Maija

2016-01-01

This article seeks to clarify the potential that Herbert Marcuse's and Theodor W. Adorno's psychoanalytic accounts may have with respect to the philosophy of education today. Marcuse and Adorno both share the view that psychoanalytic theory enables a deeper understanding of the social and biological dynamics of consciousness. For both thinkers,…

Memory, Critical Theory and the Argument from History.

ERIC Educational Resources Information Center

Cox, J. Robert

1990-01-01

Explores the function of memory in critical theory, particularly in the work of Herbert Marcuse, as the basis for a critical argumentation. Argues that Marcuse's view suggests that argument is a "re-membering" of what had been split asunder--reason, imagination, and the capacity of action. Discusses other implications of Marcuse's…

Cloth Ballistic Vest Alters Response to Blast

DTIC Science & Technology

1988-01-01

Detrick, Frederick, MD 21701-501 ELEMENT NO. NO. NO. jACCESSION NO. 11. TITLE (include Security Classification) CLOTH BALLSISTIC VEST ALTERS RESPONSE...Suppl. ’rintd in USA Cloth Ballistic Vest Alters Response to Blast YANCY Y. PHILLIPS, M.D., THOMAS G. MUNDIE, PH.D., JOHN T. YELVERTON, M.S., AND DONALD R...RICHMOND, PH.D. Ballistic wounds have been and will remain the principal cause of casualties in combat. Cloth ballistic vests (CBV) play an

A Comprehensive Program to Prepare Graduate Students for Careers in College or University Teaching

NASA Astrophysics Data System (ADS)

Krane, K. S.

1999-05-01

Although most universities do a superb job of training graduate students in research, relatively few offer training to enable M.S. or Ph.D. students to achieve the same level of mastery in teaching as a preparation for a career as a faculty member in a college or university. At Oregon State University we offer a comprehensive program that prepares students for a variety of careers in physics teaching. For students interested in teaching at a two-year college, we offer a M.S. degree with a specialty in physics education along with a strongly mentored teaching intern program at a local community college. For Ph.D. students, we offer a seminar that addresses a full range of pedagogical and methodological issues involved in physics teaching, an apprentice program that pairs each student with a faculty member of recognized teaching ability, and a capstone experience (following the completion of the Ph.D. dissertation) as an instructor to fill sabbatical or other vacancies. The impact of the program is measured by its extraordinarily high success at placing students in teaching jobs.

Groundwork for the Concept of Technique in Education: Herbert Marcuse and Technological Society

ERIC Educational Resources Information Center

Pierce, Clayton

2006-01-01

This article articulates the groundwork for a new understanding of the concept of technique through a critical engagement with Herbert Marcuse's critical theory of technology. To this end, it identifies and engages three expressions of technique in Marcuse's work: mimesis, reified labor, and the happy consciousness. It is argued that this mapping…

DOE/PSU Graduate Student Fellowship Program for Hydropower

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cimbala, John M.

The primary objective of this project is to stimulate academic interest in the conventional hydropower field by supplying research support for at least eight individual Master of Science (MS) or Doctoral (PhD) level research projects, each consisting of a graduate student supervised by a faculty member. We have completed many of the individual student research projects: 2 PhD students have finished, and 4 are still working towards their PhD degree. 4 MS students have finished, and 2 are still working towards their MS degree, one of which is due to finish this April. In addition, 4 undergraduate student projects havemore » been completed, and one is to be completed this April. These projects were supervised by 7 faculty members and an Advisory/Review Panel. Our students and faculty have presented their work at national or international conferences and have submitted several journal publications. Three of our graduate students (Keith Martin, Dan Leonard and Hosein Foroutan) have received HRF Fellowships during the course of this project. All of the remaining students are anticipated to be graduated by the end of Fall Semester 2014. All of the tasks for this project will have been completed once all the students have been graduated, although it will be another year or two until all the journal publications have been finalized based on the work performed as part of this DOE Hydropower project.« less

Early Student Support for Process Studies of Surface Freshwater Dispersal

DTIC Science & Technology

2016-06-24

Hole Oceanographic Institution REPORT NUMBER Department of Physical Oceanography - MS #29 FINAL Woods Hole, MA 02543 9. SPONSORING/MONITORING AGENCY...s proJect supports .e researc m p ysrcal oceanography of a Ph.D. student m the MIT/WHO! Jomt Program. The prOJect beoefited from, and... oceanography and has presented his work at meetings and conferences. He is working on manuscripts for publication and expects to complete his Ph.D. in 20 18

A Short Account of RRKM Theory of Unimolecular Reactions and of Marcus Theory of Electron Transfer in a Historical Perspective

ERIC Educational Resources Information Center

Di Giacomo, Francesco

2015-01-01

The RRKM Theory of Unimolecular Reactions and Marcus Theory of Electron Transfer are here briefly discussed in a historical perspective. In the final section, after a general discussion on the educational usefulness of teaching chemistry in a historical framework, hints are given on how some characteristics of Marcus' work could be introduced in…

Ray Methods for Acoustic Scattering, Optics Of Bubbles, Diffraction Catastrophes, and Nonlinear Acoustics.

DTIC Science & Technology

1992-11-24

15 Code I: Internal Reports ................................................................. 19 Code M : Oral...experiments. 13. S. M . Baumer: completed M.S. thesis in 1988 on light scattering. 14. C. E. Dean: completed Ph.D. dissertation in 1989 on light...novel oscillation induced flow instabilities. 18. J. M . Winey: awarded M.S. degree in 1990 with project on capillary wave experiments. He

Hariswaran Sitaraman | NREL

Science.gov Websites

pertaining to combustion and particulate flows. Education 2013 Ph.D., Aerospace Engineering, UT, Austin 2010 M.S., Aerospace Engineering, UT, Austin 2008 B. Tech, Aerospace Engineering, IIT Madras, Chennai

Daniel Laird | NREL

Science.gov Websites

the high-fidelity modeling, wind plant controls, and rotor dynamics focus areas. Prior to joining NREL , composite materials, and blade reliability. Education M.S. and Ph.D. in Mechanical Engineering, University

Response of the Cardiovascular System to Vibration and Combined Stresses

DTIC Science & Technology

1976-09-30

8217?rb tech:ical report has bsen reviewed and isapproved for public release IAW AFvR 190-12 (Tb).DLtrlbutlon Is unlimited* A. D . BLOSE Technical...8217 i𔃺 ft! 7 1 ACKNOWLEDGEMENTS It is a pleasure to acknowledge the collaborative efforts of D . Randall, Ph.D., Department of Physiology and...Coordinator: J. Evans, M.S.; Ph.D. Candidate: J. Marquis; Surgical I Technicians: C. Woolfolk and D . Cloyd; Data Analysts: T. Lowery, B.S., S. Beaver, B.S., M

DoD Task Force on the Prevention of the Suicide by Members of the Armed Forces

DTIC Science & Technology

2010-08-01

Ronald Green USMC Major General Philip Volpe, DO, MC USA Marjan Ghahramounlou Holloway, PhD Commander Aaron Werbel, PhD USN Table of Contents...and one civilian member serving as co-chairs for the group. Major General Philip Volpe, initially the Deputy Commander of Joint Task Force, National...and representation from each Service. Major General Philip Volpe was appointed as the military co-chair, and Ms. Bonnie Carroll was elected as the

Competent, Confident and Agile? A Study of the U.S. Army Leadership Requirements Model and its Application for U.S. Army Company Commanders

DTIC Science & Technology

2011-06-10

Thesis Committee Chair John M. Persyn, Ph.D. , Member LTC Eric K. Dunahee, M.S. , Member Robert D. Bloomquist, M.A...Accepted this 10th day of June 2011 by: , Director, Graduate Degree Programs Robert F. Baumann, Ph.D. The opinions and conclusions expressed...have been possible without the support of my committee, Dr. John M. Persyn, LTC Eric K. Dunahee and Mr. Robert D. Bloomquist. Thank you for your

Annual Faculty Research Report of the Department of Systems Engineering and the Operations Research Center for the Academic Year 2006

DTIC Science & Technology

2006-10-01

Senior Investigators: COL Darrall Henderson, Ph.D. LTC Simon R. Goerger, Ph.D. Points of Contact: NAME ADDRESS PHONE OTHER LTC Eric R. Keller...revision. Non-Refereed Publications LTC Tim Trainor*, Dr. Greg Parnell*, LTC Brigitte Kwinn*, MAJ John Brence*, CPT Eric Tollefson*, Ms. Robin Burk*, MAJ...Parnell, Brigitte Kwinn, John Brence, Eric Tollefson, Pat Downes. The US Army Uses Decision Analysis in Designing Its US Installation Regions

Marcus canonical integral for non-Gaussian processes and its computation: pathwise simulation and tau-leaping algorithm.

PubMed

Li, Tiejun; Min, Bin; Wang, Zhiming

2013-03-14

The stochastic integral ensuring the Newton-Leibnitz chain rule is essential in stochastic energetics. Marcus canonical integral has this property and can be understood as the Wong-Zakai type smoothing limit when the driving process is non-Gaussian. However, this important concept seems not well-known for physicists. In this paper, we discuss Marcus integral for non-Gaussian processes and its computation in the context of stochastic energetics. We give a comprehensive introduction to Marcus integral and compare three equivalent definitions in the literature. We introduce the exact pathwise simulation algorithm and give the error analysis. We show how to compute the thermodynamic quantities based on the pathwise simulation algorithm. We highlight the information hidden in the Marcus mapping, which plays the key role in determining thermodynamic quantities. We further propose the tau-leaping algorithm, which advance the process with deterministic time steps when tau-leaping condition is satisfied. The numerical experiments and its efficiency analysis show that it is very promising.

Employability of genetic counselors with a PhD in genetic counseling.

PubMed

Wallace, Jody P; Myers, Melanie F; Huether, Carl A; Bedard, Angela C; Warren, Nancy Steinberg

2008-06-01

The development of a PhD in genetic counseling has been discussed for more than 20 years, yet the perspectives of employers have not been assessed. The goal of this qualitative study was to gain an understanding of the employability of genetic counselors with a PhD in genetic counseling by conducting interviews with United States employers of genetic counselors. Study participants were categorized according to one of the following practice areas: academic, clinical, government, industry, laboratory, or research. All participants were responsible for hiring genetic counselors in their institutions. Of the 30 employers interviewed, 23 envisioned opportunities for individuals with a PhD degree in genetic counseling, particularly in academic and research settings. Performing research and having the ability to be a principal investigator on a grant was the primary role envisioned for these individuals by 22/30 participants. Employers expect individuals with a PhD in genetic counseling to perform different roles than MS genetic counselors with a master's degree. This study suggests there is an employment niche for individuals who have a PhD in genetic counseling that complements, and does not compete with, master's prepared genetic counselors.

A Shifting Baseline: Higher Degrees and Career Options for Ocean Scientists

NASA Astrophysics Data System (ADS)

Yoder, J. A.; Briscoe, M. G.; Glickson, D.; Roberts, S.; Spinrad, R. W.

2016-02-01

As for other fields of science, a Ph.D. degree in the ocean sciences no longer guarantees an academic position. In fact, recent studies show that while most earning a Ph.D. in the ocean sciences today may start in academia as a postdoc, an undetermined number of postdocs may not move into university faculty positions or comparable positions at basic research institutions. Although the data are few, some believe that most of those now earning Ph.D. degrees in ocean science are eventually employed outside of academia. Changes to the career path for those entering ocean science graduate programs today is both a challenge and an opportunity for graduate programs. Some graduates of course do continue in academia. For those students who are determined to follow that path, graduate programs need to prepare them for that choice. On the other hand, graduate programs also have an obligation to provide students with the information they need to make educated career decisions - there are interesting career choices other than academia for those earning a Ph.D. or finishing with a terminal M.S. degree. Furthermore, graduate programs need to encourage students to think hard about their career expectations early in their graduate program to ensure they acquire the skills needed to keep career options open. This talk will briefly review some of the recent studies related to the career paths of those who recently acquired a Ph.D. in ocean sciences and other fields; describe possible career options for those who enter ocean science graduate programs; encourage more attention on the career possibilities of a terminal ocean science M.S. degree perhaps combined with another higher degree in a different field; and discuss the skills a graduate student can acquire that increase the breadth of career path opportunities.

Diffraction Pattern Analysis as an Optical Inspection Technique

DTIC Science & Technology

1991-08-01

BACKGROUND Diameters of fiber samples have commonly been measured manually with an optical microscope. Marcuse and Presby developed an automatic...by analyzing the back-scattered light when a beam of laser light impinged upon the fiber [2]. Presby and Marcuse extended this back-scattering tech...be im- proved further in order to become a feasible method for detecting a small number of blocked openings in CRT screens. 20 REFERENCES 1. Marcuse

Grantee Spotlight: Elisa Rodriguez, Ph.D., M.S.

Cancer.gov

Dr. Elisa M. Rodriguez tests the feasibility of community-based participatory research approaches to engaging Hispanics, African Americans, and the medically underserved in the Buffalo, NY area in biospecimen donation for cancer research.

STS-89 M.S. Bonnie Dunbar, Ph.D., participates in TCDT

NASA Technical Reports Server (NTRS)

1998-01-01

STS-89 Mission Specialist Bonnie Dunbar, Ph.D., prepares to drive an M-113 armored personnel carrier as part of Terminal Countdown Demonstration Test (TCDT) activities. The TCDT is held at KSC prior to each Space Shuttle flight to provide crews with an opportunity to participate in simulated countdown activities. The STS-89 mission will be the eighth docking of the Space Shuttle with the Russian Space Station Mir. After docking, Mission Specialist Andrew Thomas, Ph.D., will transfer to the space station, succeeding David Wolf, M.D., who will return to Earth aboard Endeavour. Dr. Thomas will live and work on Mir until June. STS-89 is scheduled for a Jan. 22 liftoff at 9:48 p.m.

Teasing out specific language impairment from an autism spectrum disorder.

PubMed

Tierney, Cheryl D; Gupta, Vidya Bhushan; Angel, Alma Patricia Del; Augustyn, Marilyn

2012-04-01

Marcus is a handsome, sweet, 7½-year-old boy with a significant history of delayed development, specifically in speech and language skills, as well as difficulties with social interactions that have led other specialists to be concerned about a diagnosis of an autism spectrum disorder.He has been seen in our primary care practice since birth. He was born full-term after vaginal delivery weighing 6 pounds, 6 ounces. There were no pregnancy or delivery complications noted. Genetic testing revealed normal chromosomes, fragile X, and microarray testing. Marcus was a picky eater and good sleeper and had delays in toilet training.There is no family history of attention-deficit hyperactivity disorder (ADHD), autism, or substance abuse. Maternal grandmother and mother have a history of learning difficulties, and his father and a paternal uncle have a history of depression and anxiety. Marcus lives in a supportive environment with his mother, father, and sister.Marcus was noted to have significantly delayed language, stuttering, and immediate echolalia as a toddler. Gross and fine motor milestones were met on time, but he did not talk or follow directions until 4 to 5 years old. As a younger child, he would pretend to talk on the phone or mow the grass with a pretend lawn mower, but other household activities were not of interest to Marcus.Currently, he enjoys puzzles, reading, and board games. He likes to play with other children and can interact with familiar adults. Marcus is reported to initiate social interactions, although he has difficulty in understanding personal space. Imaginative play is preferred over other types. He seeks out adult attention and will bring objects over to an adult especially to share his perceived accomplishment. Marcus has difficulty in playing cooperatively with his sister.He is independent with activities of daily living. Marcus is noted to have auditory defensiveness including covering his ears to loud noises and becoming distressed. Parents feel he is immature and inattentive for his age. Marcus responds well when a routine is followed.Previous testing about 2 years ago revealed significant language deficits on the Clinical Evaluation of Language Functioning with average scores on the Woodcock Johnson Achievement Testing and Test of Nonverbal Intelligence Version 3. Marcus was not referred for early intervention and he did not attend preschool. In a regular education Kindergarten, he received speech and occupational therapy along with reading and math support.Comments from teachers or evaluator include the following: Marcus looked to his peers for clues about what he should be doing. Marcus has great difficulty in understanding requests but seems to be interested in pleasing his teacher and others. Marcus' language difficulty makes socialization with his peers problematic; however, he is interested in interacting with them and they seem to accept him willingly. Marcus has intent to communicate with others but relies on visual support to decipher social situations. Marcus has difficulty in attending to details and moves from activity to activity quickly. His short attention span is likely impacting not only learning but also his ability to socially interact with peers.On the day you see him for his 7-year-old checkup, he brought many toys over to show his father and interrupted your conversation to get your attention intermittently throughout the examination. He immediately pointed out a lit ceiling tile with Nemo illuminated to show his father. Marcus does not have any notable or significant repetitive motor mannerisms or stereotypies reported or observed. Marcus' gesture use was appropriate for age and included both symbolic (directing eye gaze and pointing) and concrete (hands up to be picked up and touching an item rather than pointing to it) gestures. Play observed today, although immature for age, was novel, imaginative, and functional. Answers to questions did not always match the question posed. He had a difficult time waiting for his turn before interrupting a conversation. Visual cues were helpful in understanding what was expected of him and what was going on socially.Marcus' speech is notable for persistent stuttering and difficulty in turn-taking in conversation. He gets frustrated easily and has a hard time being understood. He continues to confuse pronouns and makes some grammatical errors. He is able to follow simple directions but has a hard time following complex or multistep directions with accuracy. Nonverbal communication includes pointing to objects of interest in order to share the experience ("Look mom!"). He will point to identify an object and can follow a point across the room. He is able to use his eye contact to direct yours to moderate social interactions.Marcus has a special interest in Thomas the Tank Engine Train and Disney movies but is able to move away from those topics to engage in other play interests. Repetitive behaviors are not noted. Toe walking, hand flapping, or spinning, or unusual hand motions or observation of objects were not observed.Difficulties noted today include delays in his receptive and expressive language, poor intelligibility, dysfluency, and impaired motor planning. He recently underwent an audiogram which was normal. You decide to refer to a specialist for further evaluation.

Theoretical Studies of Low-Loss Optical Fibers.

DTIC Science & Technology

1980-09-15

on the fiber surface. Single-mode fiber operation is of interest in communications. Marcuse has shown that surface imperfections are a strong source...0.01 very small value of a : 8A at X = 1 vim Marcuse single mode 2.7 typical value of a = 1 jim, A : 10.6 vm, af = 37 Pim surface imperfections 55...Braunstein, "Scattering Losses in Single and Polycrystalline Materials for Infrared Fiber Applications," unpublished. 5. D. Marcuse , "Mode Conversion

An experimental comparison of the Marcus-Hush and Butler-Volmer descriptions of electrode kinetics applied to cyclic voltammetry. The one electron reductions of europium (III) and 2-methyl-2-nitropropane studied at a mercury microhemisphere electrode

NASA Astrophysics Data System (ADS)

Henstridge, Martin C.; Wang, Yijun; Limon-Petersen, Juan G.; Laborda, Eduardo; Compton, Richard G.

2011-11-01

We present a comparative experimental evaluation of the Butler-Volmer and Marcus-Hush models using cyclic voltammetry at a microelectrode. Numerical simulations are used to fit experimental voltammetry of the one electron reductions of europium (III) and 2-methyl-2-nitropropane, in water and acetonitrile, respectively, at a mercury microhemisphere electrode. For Eu (III) very accurate fits to experiment were obtained over a wide range of scan rates using Butler-Volmer kinetics, whereas the Marcus-Hush model was less accurate. The reduction of 2-methyl-2-nitropropane was well simulated by both models, however Marcus-Hush required a reorganisation energy lower than expected.

Plasma Cytokines Following Thermal Injury and Their Relationship with Patient Mortality, Burn Size, and Time Postburn,

DTIC Science & Technology

1993-09-01

AND TIME POSTBURN Adriana C. Drost, MS, David G. Burleson, PhD, William G. Cioffi, Jr., MD, Bryan S. Jordan, RN, MS, Arthur D. Mason, Jr., MD, and...trauma. J 2, IL-6). Science 239-502,1i988 Surg Res 48:622, 1990 7. Garmnan RD, Jacobs KA , Clark SC, et al: B-cell-stimulatory factor 23. Hack CE, De Groot

Aerodynamics of Hypersonic Lifting Vehicles: Conference Proceedings Held at the Fluid Dynamics Panel Symposium in Bristol, United Kingdom on 6-9 April 1987

DTIC Science & Technology

1987-11-01

Motion in Interactive Flows," MS Thesis , Aerospace Engineering and Engineering Mechanics Department, The University of Texas at Austin, Dec. 1986. 19...8217Cone drag in the transition from continuum to free molecular flow.’ PhD Thesis , Jesus College, Oxford (1984) 10-9 6i ______3&14 445 105.47 rn,=2.93...of Scramjets," Ph.D. Thesis , University of Sheffield (GB), October 1965. 88. Swithenbank, J., and Parsons, R.J., "Experimental Techniques for

Quantitative weaknesses of the Marcus-Hush theory of electrode kinetics revealed by Reverse Scan Square Wave Voltammetry: The reduction of 2-methyl-2-nitropropane at mercury microelectrodes

NASA Astrophysics Data System (ADS)

Laborda, Eduardo; Wang, Yijun; Henstridge, Martin C.; Martínez-Ortiz, Francisco; Molina, Angela; Compton, Richard G.

2011-08-01

The Marcus-Hush and Butler-Volmer kinetic electrode models are compared experimentally by studying the reduction of 2-methyl-2-nitropropane in acetonitrile at mercury microelectrodes using Reverse Scan Square Wave Voltammetry. This technique is found to be very sensitive to the electrode kinetics and to permit critical comparison of the two models. The Butler-Volmer model satisfactorily fits the experimental data whereas Marcus-Hush does not quantitatively describe this redox system.

Post-Polio Directory 2014: Post-Polio Clinics, Health Professionals, Support Groups

MedlinePlus

... Elizabeth Dean, DipPT, BA, MS, PhD Department of Physical Therapy University of British Columbia 212 Friedman Building, 2177 ... hu INDIA–Health Professionals Megha Sheth Lecturer in Physical Therapy SBB College of Physical Therapy, VS General Hospital ...

Meet EPA Scientist Maureen R. Gwinn, M.S. Ph.D. DABT

EPA Pesticide Factsheets

EPA biologist Dr. Maureen Gwinn works on human health hazard assessments for the Agency's IRIS program. Dr. Gwinn currently serves as the Associate Program Director for Community Health in EPA's Sustainable and Healthy Communities national research program

Ligand reorganization and activation energies in nonadiabatic electron transfer reactions

NASA Astrophysics Data System (ADS)

Zhu, Jianjun; Wang, Jianji; Stell, George

2006-10-01

The activation energy and ligand reorganization energy for nonadiabatic electron transfer reactions in chemical and biological systems are investigated in this paper. The free energy surfaces and the activation energy are derived exactly in the general case in which the ligand vibration frequencies are not equal. The activation energy is derived by free energy minimization at the transition state. Our formulation leads to the Marcus-Hush [J. Chem. Phys. 24, 979 (1956); 98, 7170 (1994); 28, 962 (1958)] results in the equal-frequency limit and also generalizes the Marcus-Sumi [J. Chem. Phys. 84, 4894 (1986)] model in the context of studying the solvent dynamic effect on electron transfer reactions. It is found that when the ligand vibration frequencies are different, the activation energy derived from the Marcus-Hush formula deviates by 5%-10% from the exact value. If the reduced reorganization energy approximation is introduced in the Marcus-Hush formula, the result is almost exact.

STS-91 M.S. Franklin Chang-Diaz and Janet Kavandi participate in CEIT

NASA Technical Reports Server (NTRS)

1998-01-01

STS-91 Mission Specialists Franklin Chang-Diaz, Ph.D., and Janet Kavandi, Ph.D., participate in the Crew Equipment Interface Test, or CEIT, in KSC's Orbiter Processing Facility Bay 2. During CEIT, the crew have an opportunity to get a hands-on look at the payloads with which they'll be working on-orbit. The STS-91 crew are scheduled to launch aboard the Shuttle Discovery for the ninth and final docking with the Russian Space Station Mir from KSC's Launch Pad 39A on May 28 at 8:05 EDT.

Analysis of Alternatives in System Capability Satisficing for Effective Acquisition

DTIC Science & Technology

2011-04-30

Technology. He received his BS in Actuarial Science from Universidad Nacional Autónoma de México, MS in Statistics, and MS and PhD in Industrial and Systems...one can view this metric (ITRLfk(i)) as “subsystem” measurement of this technology integrates within the system. In a mathematical representation...that this new metric should be a function of the different ITRLs of each technology, or in a mathematical representation: SRL_Cfk=f(ITRLfk(1), ITRLfk

Education of Students

Science.gov Websites

Operations Technology Exchange Initiating Partnerships University Partners Government Partners Industry Partnerships University Partners Government Partners Industry Partners Part of the Automotive Research Center's that are relevant to both the Army and industry. We create research opportunities for Ph.D. and M.S

77 FR 31585 - Marine Mammals; File No. 16388

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-29

... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration RIN 0648-XB154 Marine Mammals; File No. 16388 AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... Mark Baumgartner, Ph.D., Woods Hole Oceanographic Institution, MS 33 Biology Department, Woods Hole, MA...

The role of fearless dominance in differentiating psychopathy from antisocial personality disorder: comment on Marcus, Fulton, and Edens.

PubMed

Patrick, Christopher J; Venables, Noah C; Drislane, Laura E

2013-01-01

Comments on the original article by Marcus et al. (see record 2011-23134-001). Based on their meta-analytic review of the correlates of the two factors of the Psychopathic Personality Inventory (PPI), Fearless Dominance (FD) and Self-Centered Impulsivity (SCI), Marcus, Fulton, and Edens (this issue, pp. 70-79) raise important questions about the role of FD in diagnostic conceptualizations of psychopathy. In considering their findings, general limitations of metaanalyses (e.g., Ioannidis & Lau, 1999) should be borne in mind, along with specific limitations of their analysis. These limitations are discussed here.

78 FR 64504 - Advisory Committee to the Director (ACD), Centers for Disease Control and Prevention-Health...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-29

... been cancelled. Contact Person for More Information: Leandris Liburd, Ph.D., M.P.H., M.A., Designated... Road, NE., M/S K-77, Atlanta, GA 30333; Telephone (770) 488-8200, Email: [email protected] . This notice is...

STS-96 M.S. Tokarev tries gas mask as part of a TCDT

NASA Technical Reports Server (NTRS)

1999-01-01

STS-96 Mission Specialist Valery Ivanovich Tokarev, with the Russian Space Agency, tries on an oxygen gas mask during Terminal Countdown Demonstration Test (TCDT) activities at Launch Pad 39B. The TCDT provides the crew with simulated countdown exercises, emergency egress training and opportunities to inspect the mission payloads in the orbiter's payload bay. Other crew members taking part in the TCDT are Commander Kent V. Rominger, Pilot Rick Douglas Husband, and Mission Specialists Tamara E. Jernigan (Ph.D.), Daniel Barry (M.D., Ph.D.), Ellen Ochoa (Ph.D.) and Julie Payette, with the Canadian Space Agency. Scheduled for liftoff on May 20 at 9:32 a.m., STS-96 is a logistics and resupply mission for the International Space Station, carrying such payloads as a Russian crane, the Strela; a U.S.-built crane; the Spacehab Oceaneering Space System Box (SHOSS), a logistics items carrier; and STARSHINE, a student-led experiment.

Design, Implementation and Impact of the MS PHD’S Professional Development Program

NASA Astrophysics Data System (ADS)

Williamson Whitney, V.

2009-12-01

The Minorities Striving and Pursuing Higher Degrees of Success (MS PHD'S)® in Earth System Science initiative facilitates the involvement of underrepresented minority undergraduate and graduate Earth system science students in a series of activities designed to: (1) increase exposure to and engagement in the Earth system science community, via participation in scientific conferences, mentoring relationships, virtual activities, and field trips; (2) enhance professional skills, grantsmanship, oral and written communication; (3) provide funding, education and career opportunity resources; (4) facilitate networking opportunities with established researchers and educators; (5) and sustain on-going interaction, communication and support via membership within a virtual community comprised of peers, junior/senior-level researchers, and educators actively involved in facilitating full participation of minorities in the Earth system sciences. These activities, conducted in three phases, occur during professional society meetings, field trips, visits to several federal agencies, and a 'capstone' event at the National Academies. Nearly 150 Earth system science undergraduate, graduate and recent minority graduates have participated in MS PHD’S activities and are better prepared to successfully achieve their academic and professional goals. It is also expected that because of mentor-mentee partnerships, science exposure, and networking activities, MS PHD'S participants will remain actively engaged in their fields of specialization and respective professional societies. Evaluation data for MS PHD’S activities indicate that virtual and face-to-face mentoring, on-site professional development and community-building activities resulted in increased participant exposure to and engagement in the Earth system science professional community and served to better equip student participants to make informed post-baccalaureate academic and professional career decisions.

On Marcuse and Caring in Education

ERIC Educational Resources Information Center

Shel, Tammy

2006-01-01

Can caring and standardized testing coincide? Marcuse criticized the misuse of science because it also legitimizes social and economic hierarchy. By the same token, scholars develop standardized testing, claiming these tests are scientific and can measure objectively individuals' learning and intelligence capabilities. However, if inclusive caring…

Ligand reorganization and activation energies in nonadiabatic electron transfer reactions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhu Jianjun; Wang Jianji; Stell, George

2006-10-28

The activation energy and ligand reorganization energy for nonadiabatic electron transfer reactions in chemical and biological systems are investigated in this paper. The free energy surfaces and the activation energy are derived exactly in the general case in which the ligand vibration frequencies are not equal. The activation energy is derived by free energy minimization at the transition state. Our formulation leads to the Marcus-Hush [J. Chem. Phys. 24, 979 (1956); 98, 7170 (1994); 28, 962 (1958)] results in the equal-frequency limit and also generalizes the Marcus-Sumi [J. Chem. Phys. 84, 4894 (1986)] model in the context of studying themore » solvent dynamic effect on electron transfer reactions. It is found that when the ligand vibration frequencies are different, the activation energy derived from the Marcus-Hush formula deviates by 5%-10% from the exact value. If the reduced reorganization energy approximation is introduced in the Marcus-Hush formula, the result is almost exact.« less

A Case Study of URM Retention through IBP's Professional Development and Mentoring Activities

NASA Astrophysics Data System (ADS)

Johnson, A.; Williamson Whitney, V.; Ricciardi, L.; Detrick, L.; Siegfried, D.; Fauver, A.; Ithier-Guzman, W.; Thomas, S. H.; Valaitis, S.

2012-12-01

As a free-standing not for profit organization, the Institute for Broadening Participation (IBP) hosts a variety of initiatives designed to increase the retention of underrepresented minority (URM) students pursuing pathways in STEM. Successful initiatives include virtual and face-to-face components that bring together URM students with established URM and other scientists in academia, government and industry. These connections provide URM students with supportive mentoring, networking opportunities, and professional skill development contributing to an overall improved retention rate of URM students majoring in STEM degrees. IBP's initiatives include the NASA One Stop Shopping Initiative (NASA OSSI), Pathways to Ocean Science, Pathways to Engineering, and the Minorities Striving and Pursuing Higher Degrees of Success (MS PHD'S) Professional Development program in Earth System Science (ESS). The NASA OSSI initiative recruits and facilitates student engagement in NASA student education and employment opportunities. Through IBP's virtual and person-to-person communications, students learn how to identify, apply to, and participate in NASA programs. Pathways to Ocean Science connects and supports URM students with REU programs in the Ocean Sciences while serving as a resource for REU program directors. As one of IBP's newest initiatives, Pathways to Engineering has synthesized mentoring resources into an online mentoring manual for URM STEM students that has been extensively vetted by mentoring experts throughout the country. The manual which is organized by user groups serves as an e-forum providing undergraduates, graduates, postdocs, faculty members and project directors with valuable resources to facilitate a positive REU experience. This mentoring initiative also provides a mechanism for submitting new resources and inviting feedback in mentoring best practices throughout the STEM community. MS PHD'S, one of IBP's longest running and most successful initiatives, focuses on increasing the retention rate of URM students receiving advanced degrees in Earth system science. Through a three-phase structure of activities, the program addresses major barriers to retention in ESS including isolation, lack of preparation and professional development, and lack of mentoring. Program activities center on peer-to-peer community building, professional development exercises, networking experiences, one-on-one mentoring, and a facilitated virtual community. MS PHD'S participants report a reduced sense of isolation, an increased sense of community, and a higher level of confidence about their ability to succeed in their chosen field. As of August 2012, 189 students have participated in the program. 60 of those students are currently enrolled in a PhD. program. Another 35 have completed their PhD and are actively engaged in the ESS workforce.

NASA Graduate Student Researchers Program Ronald E. McNair PhD Program

NASA Technical Reports Server (NTRS)

Howard, Sunnie

1998-01-01

The NASA Ronald E. McNair PHD Program was funded in September 1995. Implementation began during the spring of 1996. The deferment of the actual program initial semester enabled the program to continue support through the fall semester of 1998. This was accomplished by a no-cost extension from August 15, 1998 through December 31, 1998. There were 12 fellows supported by the program in 1996, 15 fellows in 1997, and 15 fellows 1998. Current program capacity is 15 fellows per funding support. Support for the academic outreach component began in spring 1998. The program was named the "Good Enough" Crew Activity (GECA) in honor of Dr. McNair's philosophy of everyone being good enough to achieve anything they want bad enough. The program currently enrolls 65 students from the third through the eight grades. The program is held 12 Saturdays per semester. The time is 9:00 AM to 12:30 PM each Saturday Morning. Program direction and facilitation is jointly administered with the PHD fellows and the Saturday Academy staff. Dr. John Kelly, REM-PHD Principal Investigator serves in a program oversight and leadership capacity. Ms. Sunnie Howard, The NASA REM-PHD Administrative Coordinator serves in an administrative and logistical capacity. Mr. Aaron Hatch, the NASA-AMES Liaison Officer, serve@'in a consultative and curriculum review capacity. The first recognition activity will be held on December 12, 1998, with the students, parents, faculty, PHD fellows, and other local student support services persons. Program outreach efforts are jointly supported by the NASA REM-PHD Program and the National Space Grant College and Fellowship Program. The Ph.D. program reached its first milestone in May 1998. North Carolina A&T State University graduated the first Ph.D. fellows. The first three Ph.D. Alumni were Ronald E. McNair PHD Program Fellows. It is hoped that this is just the beginning of a highly acclaimed doctoral program. The ultimate program success will be recognized when the program begins to graduate 15 fellows per year. The Ph.D. Program is only three and a half years old and the expectations of graduating PH.D's in that timeframe, is a phenomenal accomplishment for any program in the country. Since inception of the NASA REM-PHD program, tuitions and fees have increased. Stipend support was increased to offer the Ph.D. program on a competitive basis. These increases will place allocation restraints on r_ the current level of funding. These issues are being addressed in the proposal and will bear their own merit.

Nicholas Brunhart-Lupo | NREL

Science.gov Websites

. Education Ph.D., Computer Science, Colorado School of Mines M.S., Computer Science, University of Queensland B.S., Computer Science, Colorado School of Mines Brunhart-Lupo Nicholas Brunhart-Lupo Computational Science Nicholas.Brunhart-Lupo@nrel.gov

76 FR 79202 - National Institute Of Dental & Craniofacial Research; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-21

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute Of Dental... clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of Dental and.... Krishnaraju, Ph.D., MS, Scientific Review Officer, Scientific Review Branch, National Inst of Dental...

Shawn Sheng | NREL

Science.gov Websites

experience includes mechanical and electrical system modeling and analysis, data sensing and sensor placement . Education Ph.D. in Mechanical Engineering, University of Massachusetts at Amherst; M.S. in Electrical Engineering, Institute of Electrical Engineering, Chinese Academy of Sciences; B.S. in Electrical Engineering

RACE AND UNEQUAL EXPOSURE TO POLYCHLORINATED COMPOUNDS - THE ROLE OF DIET

EPA Science Inventory

Max Weintraub, MS, Toxics Office, US Environmental Protection Agency, 75 Hawthorne Street, Mail Code CMD-4, San Francisco, CA 94105 and Linda S. Birnbaum, PhD, Experimental Toxicology Division, NHEERL, US EPA, 66 USEPA Mailroom, Research Triangle Park, NC 27711
The Centers for...

Defining a clinically meaningful effect for the design and interpretation of randomized controlled trials.

PubMed

Keefe, Richard S E; Kraemer, Helena C; Epstein, Robert S; Frank, Ellen; Haynes, Ginger; Laughren, Thomas P; McNulty, James; Reed, Shelby D; Sanchez, Juan; Leon, Andrew C

2013-05-01

This article captures the proceedings of a meeting aimed at defining clinically meaningful effects for use in randomized controlled trials for psychopharmacological agents. Experts from a variety of disciplines defined clinically meaningful effects from their perspectives along with viewpoints about how to design and interpret randomized controlled trials. The article offers relevant, practical, and sometimes anecdotal information about clinically meaningful effects and how to interpret them. The concept for this session was the work of co-chairs Richard Keefe and the late Andy Leon. Faculty included Richard Keefe, PhD; James McNulty, AbScB; Robert S. Epstein, MD, MS; Shelby D. Reed, PhD; Juan Sanchez, MD; Ginger Haynes, PhD; Andrew C. Leon, PhD; Helena Chmura Kraemer, PhD; Ellen Frank, PhD, and Kenneth L. Davis, MD. The term clinically meaningful effect is an important aspect of designing and interpreting randomized controlled trials but can be particularly difficult in the setting of psychopharmacology where effect size may be modest, particularly over the short term, because of a strong response to placebo. Payers, regulators, patients, and clinicians have different concerns about clinically meaningful effects and may describe these terms differently. The use of moderators in success rate differences may help better delineate clinically meaningful effects. There is no clear consensus on a single definition for clinically meaningful differences in randomized controlled trials, and investigators must be sensitive to specific concerns of stakeholders in psychopharmacology in order to design and execute appropriate clinical trials.

The Secret of the Winning Streak

ERIC Educational Resources Information Center

Woolley, Thomas E.; du Sautoy, Marcus P. F.

2011-01-01

In 2006, Marcus du Sautoy delivered the Royal Institution Christmas Lectures on the subject of mathematics. From this, a workshop was created using ideas illustrated in the programme. A group of mathematical students from the University of Oxford, known as Marcus' Marvellous Mathemagicians, were trained in this workshop and now travel to schools…

One-Dimensionality and Whiteness

ERIC Educational Resources Information Center

Calderon, Dolores

2006-01-01

This article is a theoretical discussion that links Marcuse's concept of one-dimensional society and the Great Refusal with critical race theory in order to achieve a more robust interrogation of whiteness. The author argues that in the context of the United States, the one-dimensionality that Marcuse condemns in "One-Dimensional Man" is best…

Strategy, National Interests, and Means to an End

DTIC Science & Technology

2007-10-01

p. 2. 13. Codevilla and Seabury, p. 251. 22 14. Ibid., pp. 92-94. 15. Ibid. 16. Ibid., pp. 84-85. 17. Ibid., p. 85. 18. Marcus Aurelius ...nor with divergent motives. Marcus Aurelius18 Somalia’s descent into chaos is well-chronicled in several publications, so additional diagnosis of

Nolan Wilson | NREL

Science.gov Websites

Nolan Wilson Nolan Wilson Postdoctoral Researcher-Chemical Engineering Nolan.Wilson@nrel.gov | 303 Ph.D., Chemical and Biomolecular Engineering, Clemson University, 2014 M.S., Chemical and Biomolecular Engineering, Clemson University, 2012 B.S., Chemical Engineering, Auburn University, 2007 Professional

Ashutosh Mittal | NREL

Science.gov Websites

@nrel.gov | 303-384-6136 Research Interests Ashutosh Mittal received an M.S. in 2004 and a Ph.D. in 2007 in Laboratory (NREL), he is actively involved in research on biomass pretreatment and conversion of biomass ., Environmental Resource Engineering, SUNY, ESF, Syracuse Professional Experience Research Scientist IV, NREL

Nathan Lee | NREL

Science.gov Websites

Economic Community of West African States, with an emphasis on Ghana, was used as a representative area of economic growth in developing countries Education Ph.D. and Diploma of Advanced Studies (M.S. equivalent members of the Economic Community of West African States, Renewable and Sustainable Energy Reviews (2014

76 FR 5183 - National Institute of Dental & Craniofacial Research; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-28

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Dental & Craniofacial Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act.... Krishnaraju, PhD, MS, Scientific Review Officer, Scientific Review Branch, National Inst. of Dental...

Full-Potential Modeling of Blade-Vortex Interactions

DTIC Science & Technology

1997-12-01

modeled by any arbitrary distribution. Stremel (ref. 23) uses a method in which the vortex is modeled with an area-weighted distribution of vorticity. A...Helicopter Rotor. Ph.D. Thesis, StanfordUniv., 1978. 23. Stremel , P. M.: Computational Methods for Non-Planar Vortex Wake Flow Fields. M.S. Thesis

Jean C. Zenklusen, M.S., Ph.D., Discusses the NCI Genomics Data Commons at AACR 2014 - TCGA

Cancer.gov

At the AACR 2014 meeting, Dr. Jean C. Zenklusen, Director of The Cancer Genome Atlas Program Office, highlights the Genomics Data Commons, a harmonized data repository that will allow simultaneous access and analysis of NCI genomics data, including The Ca

Leadership, Goals, & Transformation

ERIC Educational Resources Information Center

Barone, Carole A.

2005-01-01

John C. Hitt became the fourth president of the University of Central Florida (UCF) on March 1, 1992, after nineteen years of administrative experience and a distinguished academic career. He received his M.S. and his Ph.D. at Tulane University. Dr. Hitt serves on the boards of EDUCAUSE, the National Center for Educational Accountability, the…

The Role of Veterans Affairs in Support of DOD in Biodefense

DTIC Science & Technology

2015-05-22

Director Anthony E. Carlson, PhD , Seminar Leader Yan Poirier, LCOL, Canadian Army , Director, School of Advanced Military Studies...like them, who wield great influencing, soft power. I am also thankful to Mr. Dixon, Ms. Joranko, and all the staff of the School of Advanced Military

An Inventory and Safety Stock Analysis of Air Force Medical Service Pharmaceuticals

DTIC Science & Technology

2015-03-26

Adam D. Reiman , PhD Member AFIT-ENS-MS-15-M-133 iv Abstract A significant challenge facing the Air Force Medical Service (AFMS...sincere gratitude to my research committee, Dr. William Cunningham and Lt Col Adam Reiman for their guidance and support throughout the research

Construction of a multicontrol sterility system for a maize male-sterile line and hybrid seed production based on the ZmMs7 gene encoding a PHD-finger transcription factor.

PubMed

Zhang, Danfeng; Wu, Suowei; An, Xueli; Xie, Ke; Dong, Zhenying; Zhou, Yan; Xu, Liwen; Fang, Wen; Liu, Shensi; Liu, Shuangshuang; Zhu, Taotao; Li, Jinping; Rao, Liqun; Zhao, Jiuran; Wan, Xiangyuan

2018-02-01

Although hundreds of genetic male sterility (GMS) mutants have been identified in maize, few are commercially used due to a lack of effective methods to produce large quantities of pure male-sterile seeds. Here, we develop a multicontrol sterility (MCS) system based on the maize male sterility 7 (ms7) mutant and its wild-type Zea mays Male sterility 7 (ZmMs7) gene via a transgenic strategy, leading to the utilization of GMS in hybrid seed production. ZmMs7 is isolated by a map-based cloning approach and encodes a PHD-finger transcription factor orthologous to rice PTC1 and Arabidopsis MS1. The MCS transgenic maintainer lines are developed based on the ms7-6007 mutant transformed with MCS constructs containing the (i) ZmMs7 gene to restore fertility, (ii) α-amylase gene ZmAA and/or (iii) DNA adenine methylase gene Dam to devitalize transgenic pollen, (iv) red fluorescence protein gene DsRed2 or mCherry to mark transgenic seeds and (v) herbicide-resistant gene Bar for transgenic seed selection. Self-pollination of the MCS transgenic maintainer line produces transgenic red fluorescent seeds and nontransgenic normal colour seeds at a 1:1 ratio. Among them, all the fluorescent seeds are male fertile, but the seeds with a normal colour are male sterile. Cross-pollination of the transgenic plants to male-sterile plants propagates male-sterile seeds with high purity. Moreover, the transgene transmission rate through pollen of transgenic plants harbouring two pollen-disrupted genes is lower than that containing one pollen-disrupted gene. The MCS system has great potential to enhance the efficiency of maize male-sterile line propagation and commercial hybrid seed production. © 2017 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd.

On the relation between Marcus theory and ultrafast spectroscopy of solvation kinetics

NASA Astrophysics Data System (ADS)

Roy, Santanu; Galib, Mirza; Schenter, Gregory K.; Mundy, Christopher J.

2018-01-01

The phenomena of solvent exchange control the process of solvating ions, protons, and charged molecules. Building upon our extension of Marcus' philosophy of electron transfer, we provide a new perspective of ultrafast solvent exchange mechanism around ions measurable by two-dimensional infrared (2DIR) spectroscopy. In this theory, solvent rearrangement drives an ion-bound water to an activated state of higher coordination number, triggering ion-water separation that leads to the solvent-bound state of the water molecule. This ion-bound to solvent-bound transition rate for a BF4--water system is computed using ab initio molecular dynamics and Marcus theory, and is found to be in excellent agreement with the 2DIR measurement.

Marcus-Hush-Chidsey theory of electron transfer to and from species bound at a non-uniform electrode surface: Theory and experiment

NASA Astrophysics Data System (ADS)

Henstridge, Martin C.; Batchelor-McAuley, Christopher; Gusmão, Rui; Compton, Richard G.

2011-11-01

Two simple models of electrode surface inhomogeneity based on Marcus-Hush theory are considered; a distribution in formal potentials and a distribution in electron tunnelling distances. Cyclic voltammetry simulated using these models is compared with that simulated using Marcus-Hush theory for a flat, uniform and homogeneous electrode surface, with the two models of surface inhomogeneity yielding broadened peaks with decreased peak-currents. An edge-plane pyrolytic graphite electrode is covalently modified with ferrocene via 'click' chemistry and the resulting voltammetry compared with each of the three previously considered models. The distribution of formal potentials is seen to fit the experimental data most closely.

Contact/Disability Performance. An Essay Constructed between Petra Kuppers and Neil Marcus

ERIC Educational Resources Information Center

Kuppers, Petra; Marcus, Neil

2009-01-01

This dialogue discusses disability and performance through poetic interrogation, interspersed with segments of Neil Marcus's play "My Sexual History." The authors touch on such topics such as sexuality and representation, dance and theatre, the management of disability staring, speech difference and writing, curiosity and shrouding. (Contains 1…

Marcus Theory: Thermodynamics CAN Control the Kinetics of Electron Transfer Reactions

ERIC Educational Resources Information Center

Silverstein, Todd P.

2012-01-01

Although it is generally true that thermodynamics do not influence kinetics, this is NOT the case for electron transfer reactions in solution. Marcus Theory explains why this is so, using straightforward physical chemical principles such as transition state theory, Arrhenius' Law, and the Franck-Condon Principle. Here the background and…

Critical Social Theory: A Portrait

ERIC Educational Resources Information Center

Torres, Carlos A.

2012-01-01

The term Critical Social Theory is employed in this article following the tradition of the Frankfurt School, and particularly the work of Herbert Marcuse and his interpretation of the political and social philosophy of Hegel and Marx. Discussing the contribution of G.W.F. Hegel to social theory Marcuse argued that: "Hegel's system brings to a…

Rudolph A. Marcus and His Theory of Electron Transfer Reactions

Science.gov Websites

early 1950s and soon discovered ... a strong experimental program at Brookhaven on electron-transfer experimental work provided the first verification of several of the predictions of his theory. This, in turn Marcus theory, namely, experimental evidence for the so-called "inverted region" where rates

Critical Theory and Information Studies: A Marcusean Infusion

ERIC Educational Resources Information Center

Pyati, Ajit K.

2006-01-01

In the field of library and information science, also known as information studies, critical theory is often not included in debates about the discipline's theoretical foundations. This paper argues that the critical theory of Herbert Marcuse, in particular, has a significant contribution to make to the field of information studies. Marcuse's…

Reassessing Subjectivity, Criticality, and Inclusivity: Marcuse's Challenge to Adult Education.

ERIC Educational Resources Information Center

Brookfield, Stephen

2002-01-01

Although Herbert Marcuse did not write as an adult educator, his analysis of subjectivity, criticality, and inclusivity has implications for adult education. He demonstrated how apparently humanistic tolerance for diversity can be manipulated to reinforce dominant ideology, and he made a case for aesthetic education as a site for critical…

Metallurgical Characterization of the Interfaces and the Damping Mechanisms in Metal Matrix Composites.

DTIC Science & Technology

1986-09-30

Il.g. Honors, Awards - none II.h. Participants :Mr. Asok Ray ; Graduate Student working towards his Ph.D. Thesis. Advisor: Dr. V.K. Kinra at Texas A&M...Presentations ll.d.1 Invited Presentation at Topical or Scientific/Technical Society Conferences i) A.K. Ray , V.K. Kinra, S.P. Rawal and M.S. Misra...FC16 ii) S.P. Rawal, J.H. Armstrong, M.S. Misra, A.K. Ray and V.K. Kinra, "Damping Measurements of Gr/AI Composites", Symposium on Dynamic Behavior of

Defining a Clinically Meaningful Effect for the Design and Interpretation of Randomized Controlled Trials

PubMed Central

Kraemer, Helena C.; Epstein, Robert S.; Frank, Ellen; Haynes, Ginger; Laughren, Thomas P.; Mcnulty, James; Reed, Shelby D.; Sanchez, Juan; Leon, Andrew C.

2013-01-01

Objective: This article captures the proceedings of a meeting aimed at defining clinically meaningful effects for use in randomized controlled trials for psychopharmacological agents. Design: Experts from a variety of disciplines defined clinically meaningful effects from their perspectives along with viewpoints about how to design and interpret randomized controlled trials. Setting: The article offers relevant, practical, and sometimes anecdotal information about clinically meaningful effects and how to interpret them. Participants: The concept for this session was the work of co-chairs Richard Keefe and the late Andy Leon. Faculty included Richard Keefe, PhD; James McNulty, AbScB; Robert S. Epstein, MD, MS; Shelby D. Reed, PhD; Juan Sanchez, MD; Ginger Haynes, PhD; Andrew C. Leon, PhD; Helena Chmura Kraemer, PhD; Ellen Frank, PhD, and Kenneth L. Davis, MD. Results: The term clinically meaningful effect is an important aspect of designing and interpreting randomized controlled trials but can be particularly difficult in the setting of psychopharmacology where effect size may be modest, particularly over the short term, because of a strong response to placebo. Payers, regulators, patients, and clinicians have different concerns about clinically meaningful effects and may describe these terms differently. The use of moderators in success rate differences may help better delineate clinically meaningful effects. Conclusion: There is no clear consensus on a single definition for clinically meaningful differences in randomized controlled trials, and investigators must be sensitive to specific concerns of stakeholders in psychopharmacology in order to design and execute appropriate clinical trials. PMID:23882433

STS-89 M.S. Andrew Thomas, Ph.D., participates in TCDT

NASA Technical Reports Server (NTRS)

1998-01-01

STS-89 Mission Specialist Andrew Thomas, Ph.D., participates in a question and answer session for the media as part of Terminal Countdown Demonstration Test (TCDT) activities. The TCDT is held at KSC prior to each Space Shuttle flight to provide crews with an opportunity to participate in simulated countdown activities. The STS-89 mission will be the eighth docking of the Space Shuttle with the Russian Space Station Mir. After docking, Dr. Thomas will transfer to the space station, succeeding David Wolf, M.D., who will return to Earth aboard Endeavour. Dr. Thomas will live and work on Mir until June. STS-89 is scheduled for a Jan. 22 liftoff at 9:48 p.m.

Gender Diversity in the Geosciences: Current Status and Future Trends

NASA Astrophysics Data System (ADS)

Holmes, M.; O'Connell, S.; Frey, C.; Ongley, L. K.

2002-12-01

Since 1995, the proportion of women in the American Geological Institute's Directory of Geoscience Departments has risen from 12% of the entries to 14.2% (exclusive of administrative assistants). Separated into type of institution, there is a greater proportion of women at Museums (17.5%), Bachelor's-granting institutions (17.2%), and non degree-granting academic institutions (16.5%), but these percentages drop when marginal positions, such as "Lecturer", "Instructor", "Adjunct" and "Cooperating Faculty" are excluded to 14.0% (Museums), 15.9% (B.S.-granting institution). The institutions with the lowest proportion of females are the State Geologic Surveys (12.6% female), followed by Ph.D.-granting institutions (12.8% female). Fifteen Ph.D.-granting institutions in the United States still have no females on their faculty. These numbers contrast poorly with the proportion of women receiving B.S. or M.S. degrees in the geosciences over the last 10 years (34 B.S.%/30% M.S. in 1996) and with the proportion receiving the PhD. (24% over the last 10 years; 30% in 2000). There is a significant loss of women between the M.S. and Ph.D. degrees, and between the Ph.D. degree and a tenure-track position. Women reach or exceed their overall average in four subdisciplines of the geosciences: paleontology, geochemistry, general geology, and oceanography. Women are most under-represented in engineering geology, followed by economic geology, planetology, soil science, geophysics, and hydrology. Within these subdisciplines, women exceed their overall average in geomagnetism and paleomagnetism, ground water and surface water studies, soil biochemistry, and meteorite study. Most women in tenure-track positions at degree-granting institutions are currently Assistant Professors while most men are Full Professors. The proportion of women hired into Assistant Professor positions has increased over the last five years, from 22% hired 5 to 10 years ago to 25% hired 1 to 5 years ago. These data indicate that women are beginning to approach being hired at the same proportion in which they receive PhD degrees in the geosciences. Despite common myth, women are not getting "all" of the new Assistant Professor positions; they remain under-represented at every academic rank, at every type of institution. At the current rate of increase, we expect women will not achieve parity in the geosciences for another 40 years.

Xiaowen Chen | NREL

Science.gov Websites

Xiaowen Chen Photo of Xiaowen Chen Xiaowen Chen Researcher IV-Chemical Engineering Xiaowen.Chen Education Ph.D., Chemical Engineering, University of Maine, 2009 M.S., Chemical Engineering, University of Maine, 2005 B.S., Chemical Engineering in Polymer Science and Technology, Nanjing University of Science

COLLOIDAL FOULING OF MEMBRANES: IMPLICATIONS IN THE TREATMENT OF TEXTILE DYE WASTES AND WATER REUSE

EPA Science Inventory

Three manuscripts are in preparation for submission to refereed journals based on the MS Thesis of the student supported by this work. This student will continue work towards the Ph.D. on a related topic with other sources of funding upon completion of this project...

Salary Survey: Chemists' Salaries Move Higher This Year.

ERIC Educational Resources Information Center

Chemical and Engineering News, 1981

1981-01-01

Presents in tabular form chemists' salaries. Reviews salaries of chemists with B.S., M.S., and Ph.D. degrees, chemical engineers, college faculty, industrial chemists, women, and employment status of chemists surveyed. Indicates relatively low unemployment and that medial salary for chemists has increased 11% between March 1980 and March 1981. (JN)

Calibrating Crash Modification Factors for Wyoming-Specific Conditions : Application of the Highway Safety Manual - Part D

DOT National Transportation Integrated Search

2017-04-01

Mohamed Ahmed, Ph.D., P.E.- orcid.org/0000-0002-1921-0724; Sherif Gaweesh, M.S. - orcid.org/0000-0001-7977-6378; Md Julfiker Hossain -orcid.org/0000-0001-7173-7040; Sadia Sharmin orcid.org/0000-0003-0947-8345; Thomas Peel orcid.org/ 0000-0002...

Expanding Your Coverage of Neuroscience: An Interview with Michael Gazzaniga

ERIC Educational Resources Information Center

Rasmussen, Erin B.

2006-01-01

Erin Rasmussen is an Assistant Professor in the Department of Psychology at Idaho State University where she teaches learning, behavioral pharmacology, senior seminar, and introductory psychology. She received her MS and PhD in experimental psychology (with a minor in behavioral pharmacology and toxicology) from Auburn University. She taught at…

Reviving Graduate Seminar Series through Non-Technical Presentations

ERIC Educational Resources Information Center

Madihally, Sundararajan V.

2011-01-01

Most chemical engineering programs that offer M.S. and Ph.D. degrees have a common seminar series for all the graduate students. Many would agree that seminars lack student interest, leading to ineffectiveness. We questioned the possibility of adding value to the seminar series by incorporating non-technical topics that may be more important to…

Advancing the understanding of progression in multiple sclerosis: an interview with Shibeshih Belachew.

PubMed

Belachew, Shibeshih

2018-02-01

Shibeshih Belachew speaks to Laura Dormer, Commissioning Editor: Dr Shibeshih Belachew, MD, PhD, is a Senior Medical Director for Multiple Sclerosis (MS) Disease Area in Global Product Development Medical Affairs at Roche (Basel, Switzerland). Prior to joining Roche in January 2016, he was Director of MS Franchise and Head of Medical Director's office for Biogen Region Europe and Canada. Previously at Biogen he also served as a Director in Global Neurology for the natalizumab program in Cambridge (MA, USA). Prior to joining industry, he was a Clinical Professor of Neurology at the University of Liège in Belgium. Shibeshih completed neurology postgraduate training at the University of Liège and has a PhD in Biomedical Science in the field of Developmental Neurobiology. Shibeshih has been a post-doctoral fellow in the Laboratory of Cellular and Synaptic Neurophysiology at the National Institutes of Health (Bethesda, MD, USA) and later at the Center for Neuroscience Research of Children's National Medical Center in Washington DC. He is a member of the Belgian Neurological Society.

STS-87 M.S. Takao Doi, Ph.D., of NASDA after landing

NASA Technical Reports Server (NTRS)

1997-01-01

STS-87 Mission Specialist Takao Doi, Ph.D., of the National Space Development Agency (NASDA) of Japan greets a NASDA official shortly after the orbiter Columbia returned to KSC, touching down on Runway 33 at KSC's Shuttle Landing Facility. STS-87 concluded its mission with a main gear touchdown at 7:20:04 a.m. EST Dec. 5, drawing the 15-day, 16-hour and 34-minute-long mission of 6.5 million miles to a close. Also onboard the orbiter were Commander Kevin Kregel; Pilot Steven Lindsey; Mission Specialists Winston Scott and Kalpana Chawla, Ph.D.; and Payload Specialist Leonid Kadenyuk of the National Space Agency of Ukraine. During the 88th Space Shuttle mission, the crew performed experiments on the United States Microgravity Payload-4 and pollinated plants as part of the Collaborative Ukrainian Experiment. This was the 12th landing for Columbia at KSC and the 41st KSC landing in the history of the Space Shuttle program.

STS-96 M.S. Payette and Pilot Husband try on gas masks as part of a TCDT

NASA Technical Reports Server (NTRS)

1999-01-01

At Launch Pad 39B, STS-96 Mission Specialist Julie Payette, with the Canadian Space Agency, and Pilot Rick Douglas Husband practice putting on oxygen gas masks as part of Terminal Countdown Demonstration Test (TCDT) activities. The TCDT provides the crew with emergency egress traiing, simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. Other crew members taking part in the TCDT are Commander Kent V. Rominger and Mission Specialists Tamara E. Jernigan (Ph.D.), Daniel Barry (M.D., Ph.D.), Ellen Ochoa (Ph.D.) and Valery Ivanovich Tokarev, with the Russian Space Agency. Scheduled for liftoff on May 20 at 9:32 a.m., STS- 96 is a logistics and resupply mission for the International Space Station, carrying such payloads as a Russian crane, the Strela; a U.S.-built crane; the Spacehab Oceaneering Space System Box (SHOSS), a logistics items carrier; and STARSHINE, a student- led experiment.

Synthesis and Magnetic, Thermal, and Electrical Measurements on Complex non-Cuprate Superconductors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Henry, Laurence L

2006-02-27

The project investigated superconductivity in non-cuprate materials with critical temperatures, T{sub c}, in excess of 20 K in order to understand the thermodynamics of several of these materials. The project is a cooperative effort between investigators at Southern University (SU), Louisiana State University (LSU), and Los Alamos National Laboratory (LANL). It involved synthesis of high quality samples, and subsequent detailed magnetic, thermal and electrical measurements on them. The project provided a PhD Thesis research experience and training for a graduate student, Ms. Robin Macaluso. High quality, single crystal samples were synthesized by Ms. Macaluso under the direction of one ofmore » the CO-PIS, John Sarao, during the summer while she was a visitor at LANL being supported by this grant. On these samples magnetic measurements were performed at SU, thermal and electrical measurements were made in the LSU Physics and Astronomy Department. The crystallographic properties were determined in the LSU Chemistry Department by Ms. Macaluso under the direction of her dissertation advisor, Dr. Julia Chan. Additional high field magnetic measurements on other samples were performed at the National High Magnetic Field Laboratory (NHMFL) both in Tallahassee and at LANL. These measurements involved another graduate student, Umit Alver, who used some of the measurements as part of his PhD dissertation in Physics at LSU.« less

Hyperbolic metamaterial nanostructures to tune charge-transfer dynamics (Conference Presentation)

NASA Astrophysics Data System (ADS)

Lee, Kwang Jin; Xiao, Yiming; Woo, Jae Heun; Kim, Eun Sun; Kreher, David; Attias, André-Jean; Mathevet, Fabrice; Ribierre, Jean-Charles; Wu, Jeong Weon; André, Pascal

2016-09-01

Charge transfer (CT) is an essential phenomenon relevant to numerous fields including biology, physics and chemistry.1-5 Here, we demonstrate that multi-layered hyperbolic metamaterial (HMM) substrates alter organic semiconductor CT dynamics.6 With triphenylene:perylene diimide dyad supramolecular self-assemblies prepared on HMM substrates, we show that both charge separation (CS) and charge recombination (CR) characteristic times are increased by factors of 2.5 and 1.6, respectively, resulting in longer-lived CT states. We successfully rationalize the experimental data by extending Marcus theory framework with dipole image interactions tuning the driving force. The number of metal-dielectric pairs alters the HMM interfacial effective dielectric constant and becomes a solid analogue to solvent polarizability. Based on the experimental results and extended Marcus theory framework, we find that CS and CR processes are located in normal and inverted regions on Marcus parabola diagram, respectively. The model and further PH3T:PCBM data show that the phenomenon is general and that molecular and substrate engineering offer a wide range of kinetic tailoring opportunities. This work opens the path toward novel artificial substrates designed to control CT dynamics with potential applications in fields including optoelectronics, organic solar cells and chemistry. 1. Marcus, Rev. Mod. Phys., 1993, 65, 599. 2. Marcus, Phys. Chem. Chem. Phys., 2012, 14, 13729. 3. Lambert, et al., Nat. Phys., 2012, 9, 10. 4. C. Clavero, Nat. Photon., 2014, 8, 95. 5. A. Canaguier-Durand, et al., Angew. Chem. Int. Ed., 2013, 52, 10533. 6. K. J. Lee, et al., Submitted, 2015, arxiv.org/abs/1510.08574.

A Dense Corpus Study of Past Tense and Plural Overregularization in English.

ERIC Educational Resources Information Center

Maslen, Robert J.C.; Theakson, Anna L.; Lieven, Elena V.M.; Tomasello, Michael

2004-01-01

In the "blocking-and-retrieval-failure" account of overregularization (OR; G. F. Marcus, 1995; G. F. Marcus et al., 1992), the claim that a symbolic rule generates regular inflection is founded on pervasively low past tense OR rates and the lack of a substantive difference between past tense and plural OR rates. Evidence of extended periods of OR…

Thanatos and Civilization: Lacan, Marcuse, and the Death Drive

ERIC Educational Resources Information Center

Cho, Daniel

2006-01-01

During the 1950s and 1960s two thinkers, Herbert Marcuse and Jacques Lacan, were conducting a "return to Freud" for very similar reasons. If the differences between them are often advertised, their affinities are less so. In this article, I examine how their "return to Freud" and fidelity to psychoanalysis serves as a common ground to read each in…

John Lewis | NREL

Science.gov Websites

Lewis John Lewis John Lewis Researcher IV-Chemical Engineering John.Lewis@nrel.gov | 303-275-3021 Education Ph.D. Chemical Engineering, California Institute of Technology, Pasadena, CA, 1996 M.S. Chemical Engineering, California Institute of Technology, Pasadena, CA, 1993 B.S. Chemical Engineering, Texas A&M

75 FR 37449 - Proposed Data Collections Submitted for Public Comment and Recommendations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-29

... on proposed data collection projects, the Centers for Disease Control and Prevention (CDC) will... Maryam I. Daneshvar, Ph.D., CDC Reports Clearance Officer, 1600 Clifton Road, MS-D74, Atlanta, GA 30333 or send an e-mail to [email protected]cdc.gov . Comments are invited on: (a) Whether the proposed collection of...

William Wolfgang Brickman, 1913-86.

ERIC Educational Resources Information Center

Parker, Franklin

William Wolfgang Brickman, founding member and President, 1956-59, of the Comparative and International Education Society, died June 22, 1986, in a Philadelphia hospital leukemia unit. Born June 30, 1913, in New York City, he attended city schools and earned B.A. and M.S. degrees at City College, a New York University Ph.D. and an honorary M.A.…

Degrees Conferred by Schools and Colleges of Pharmacy for the Academic Year 1980-81.

ERIC Educational Resources Information Center

Chasin, Steven H.

1982-01-01

Degrees conferred in 72 pharmacy schools (B.S., B.Pharm., Pharm.D., M.S., Ph.D., and honorary) are tabulated by college, state, and region and ethnic/minority group. Overall, the number of degrees declined five percent, following a downward trend begun in 1977-78, with variation by specific degree. (MSE)

Academic Women Chemists in the 20th Century: Past, Present, Projections.

ERIC Educational Resources Information Center

Roscher, Nina Matheny; Cavanaugh, Margaret A.

1987-01-01

The number of women obtaining degrees in chemistry has increased and many indicators suggest that the trend will continue. The percentage of women obtaining BS, MS, and PhD degrees in chemistry is also expected to continue to rise. Doctoral women chemists are beginning to be distributed in governmental, academic, and industrial workplaces in the…

Lincoln Advanced Science and Engineering Reinforcement

DTIC Science & Technology

1989-01-01

Chamblee Physics Lincoln University Kelvin Clark Physics Lincoln University Dwayne Cole Mechanical Engineering Howard University Francis Countiss Physics...Mathematics Lincoln University Spencer Lane Mechanical Engineering Howard University Edward Lawerence Physics Lincoln University Cyd Hall Actuarial Science...Pittsburgh Lloyd Hammond Ph.D., Bio-Chemistry Purdue University Timothy Moore M.S., Psychology Howard University * completedI During 1988, three (3

Political Authoritarianism and Economic Success in Indonesia and South Korea

DTIC Science & Technology

2017-06-01

ECONOMIC SUCCESS IN INDONESIA AND SOUTH KOREA by Marcus A. Johnson June 2017 Thesis Advisor: Naazneen Barma Second Reader: Robert Weiner THIS PAGE...4. TITLE AND SUBTITLE POLITICAL AUTHORITARIANISM AND ECONOMIC SUCCESS IN INDONESIA AND SOUTH KOREA 5. FUNDING NUMBERS 6. AUTHOR(S) Marcus A...CODE 13. ABSTRACT (maximum 200 words) This thesis researches the features of political authoritarianism that might contribute to economic success

An Assessment of Nonresponse Bias in Mail Surveys of Naval Personnel

DTIC Science & Technology

1976-02-01

Hollowell, Ida Harloff, and Marge Covher. Special thanks are due to Jim Herbert who spent many hours keep- ing track of cases, tabulating, and...volunteering for psychological experiments has revealed that the type of experiment (Martin & Marcuse , 1958), the alterna- tives to participating...M., & Marcuse , F. L. Characteristics of volunteers and nonvol- unteers in psychological experimentation. Journal of Consulting Psychology, 1958

Surface hopping with a manifold of electronic states. III. Transients, broadening, and the Marcus picture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dou, Wenjie; Subotnik, Joseph E.; Nitzan, Abraham

2015-06-21

In a previous paper [Dou et al., J. Chem. Phys. 142, 084110 (2015)], we have introduced a surface hopping (SH) approach to deal with the Anderson-Holstein model. Here, we address some interesting aspects that have not been discussed previously, including transient phenomena and extensions to arbitrary impurity-bath couplings. In particular, in this paper we show that the SH approach captures phonon coherence beyond the secular approximation, and that SH rates agree with Marcus theory at steady state. Finally, we show that, in cases where the electronic tunneling rate depends on nuclear position, a straightforward use of Marcus theory rates yieldsmore » a useful starting point for capturing level broadening. For a simple such model, we find I-V curves that exhibit negative differential resistance.« less

Blinking suppression of CdTe quantum dots on epitaxial graphene and the analysis with Marcus electron transfer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hirose, Takuya; Tamai, Naoto, E-mail: tamai@kwansei.ac.jp; Kutsuma, Yasunori

We have prepared epitaxial graphene by a Si sublimation method from 4H-SiC. Single-particle spectroscopy of CdTe quantum dots (QDs) on epitaxial graphene covered with polyvinylpyrrolidone (PVP) or polyethylene glycol (PEG) showed the suppression of luminescence blinking and ∼10 times decreased luminescence intensity as compared with those on a glass. The electronic coupling constant, H{sub 01}, between CdTe QDs and graphene was calculated to be (3.3 ± 0.4) × 10{sup 2 }cm{sup −1} in PVP and (3.7 ± 0.8) × 10{sup 2 }cm{sup −1} in PEG based on Marcus theory of electron transfer and Tang-Marcus model of blinking with statistical distribution.

Analysis of S2QA- charge recombination with the Arrhenius, Eyring and Marcus theories.

PubMed

Rantamäki, Susanne; Tyystjärvi, Esa

2011-01-01

The Q band of photosynthetic thermoluminescence, measured in the presence of a herbicide that blocks electron transfer from PSII, is associated with recombination of the S(2)Q(A)(-) charge pair. The same charge recombination reaction can be monitored with chlorophyll fluorescence. It has been shown that the recombination occurs via three competing routes of which one produces luminescence. In the present study, we measured the thermoluminescence Q band and the decay of chlorophyll fluorescence yield after a single turnover flash at different temperatures from spinach thylakoids. The data were analyzed using the commonly used Arrhenius theory, the Eyring rate theory and the Marcus theory of electron transfer. The fitting error was minimized for both thermoluminescence and fluorescence by adjusting the global, phenomenological constants obtained when the reaction rate theories were applied to the multi-step recombination reaction. For chlorophyll fluorescence, all three theories give decent fits. The peak position of the thermoluminescence Q band is correct by all theories but the form of the Q band is somewhat different in curves predicted by the three theories. The Eyring and Marcus theories give good fits for the decreasing part of the thermoluminescence curve and Marcus theory gives the closest fit for the rising part. Copyright © 2011 Elsevier B.V. All rights reserved.

Clinical Investigation Program Annual Progress Report.

DTIC Science & Technology

1985-09-30

027 78/114 In Vitro Effect of Minoxidil on Collagen Produc- tion by Normal and Scleroderma Fibroblasts (C) (PR...effect of minoxidil on collagen production Dy normal and scleroderma fibroblasts. Previously titled: The use of minoxidil in treating progressive...Svc: (tO) Assoc Investigators: (11) Key Words: scleroderma, minoxidil Thomas P. O’Barr PhD, DAC fibroblasts, collagen Ellen Swanson MS, DAC Don

Journalism Abstracts: M.A., M.S., Ph.D. Theses in Journalism and Mass Communication. Vol. 14.

ERIC Educational Resources Information Center

Popovich, Mark N., Ed.

This book is an annual compilation of master's theses and doctoral dissertations written in schools and departments of journalism and communication in the United States. The aim of the book is to improve the flow of information about current research to students and teachers in journalism schools, to scholars in related disciplines, and to…

Obituary: Frank Albini, 1936-2005

Treesearch

Pat Andrews

2006-01-01

Frank Albini, fire behavior research scientist from 1973 to 1985, died of cancer at the age of 69 on 3 December 2005. He was born in Madera, California, where he graduated from high school. He attended the California Institute of Technology and earned a BS in Aeronautical Engineering in 1958, and a year later an MS in Mechanical Engineering. He was awarded a PhD in...

Journalism Abstracts: M.A., M.S., Ph.D. Theses in Journalism and Mass Communication. Vol. 10.

ERIC Educational Resources Information Center

Hall, William E., Ed.

This annual compilation by the Association for Education in Journalism describes master's theses and doctoral dissertations written in schools and departments of journalism and communication in the United States between July 1, 1971, and June 30, 1972. The aim of the book is to improve the flow of information about current research to students and…

75 FR 22816 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Revitalizing Core...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-30

...(c)(4) and (6), Title 5, U.S.C., and the Determination of the Director, Management Analysis and..., PhD, M.P.H., NCIPC/ERPO, CDC, 4770 Buford Highway, NE., M/S F62, Atlanta, Georgia 30341-3724... and Prevention. [FR Doc. 2010-10164 Filed 4-29-10; 8:45 am] BILLING CODE 4163-18-P ...

EFFECT OF INHALED ENDOTOXIN ON AIRWAY AND CIRCULATING INFLAMMATORY CELL PHAGOCYTOSIS AND CD11B EXPRESSION IN ATOPIC ASTHMATIC SUBJECTS

EPA Science Inventory

Effect of inhaled endotoxin on airway and circulating inflammatory cell phagocytosis and CD11b expression in atopic asthmatic subjects

Neil E. Alexis, PhD, Marlowe W. Eldridge, MD, David B. Peden, MD, MS

Chapel Hill and Research Triangle Park, NC

Backgrou...

Doctors aren't immune to theft and fraud

PubMed Central

Marcus, Gary

1995-01-01

A chartered accountant says the problem of fraud within medical practices is far from rare, even though prevention is relatively simple. Gary Marcus provides advice to physicians about ways to spot fraud within their practices and things they can do to prevent it. No matter how small your practice or how long you have had the same employees, says Marcus, given the right circumstances anyone might steal from you. Imagesp940-a PMID:7697586

Environmental Assessment for Pond Target at the South Range of the Utah Test and Training Range

DTIC Science & Technology

2004-11-01

Christenson, 1988 , Shallow Ground Water and Related Hazards in Utah) Mr. Marcus Blood, the Hill AFB Natural Resources Manager, has reported a shallow...Christenson, 1988 , Shallow Ground Water and Related Hazards in Utah) Mr. Marcus Blood, the Hill AFB Natural Resources Manager, has reported a shallow...Complex Cultural Resource Inventory, Wendover Air Force Range, Tooele County, Utah, March 1999. Cronquist , A ., Holmgren, A.H., Holmgren, N.H

Moral, Ethical, and Psychological Preparation of Soldiers and Units for Combat

DTIC Science & Technology

2011-01-01

Stoic phi los o pher Marcus Aurelius ob served, “Re spect be comes con crete through em pa thy.” Cicero re - minds us that a sol dier’s re spect must...build ing trust with the pop u la tion ought to be M C M A S T E R 1 3 * Marcus Tullius Cicero, On Du ties, ed. and trans. M. T. Grif fin and E. M. Atkins

A new sexual revolution? Critical theory, pornography, and the Internet.

PubMed

Garlick, Steve

2011-08-01

The "sexual revolution" was a central element of North American culture in the 1960s. Today, sex is increasingly central to mainstream culture, in large part due to the Internet, and we might wonder whether we are living through a comparable period of sexual history. In this article, I revisit the work of Herbert Marcuse-the original theorist of the sexual revolution-to ask whether it can contribute to a critical theory of sexuality in the era of digital technology. After outlining Marcuse's theory of the role of Eros in social life, I discuss two pornographic Web sites that combine eroticism and social critique. I argue that Marcuse's work is valuable for its emphasis on the intersection of sex, technology, and capitalist economy, but that it needs to be supplemented by a focus on masculinity and the male body in Internet pornography.

Metal cation exchange reactions of ore minerals in Fe-Mn crusts of the Marcus Wake Rise (Pacific Ocean) in aqueous-salt solutions

NASA Astrophysics Data System (ADS)

Novikov, G. V.; Bogdanova, O. Yu.; Melnikov, M. E.; Drozdova, A. N.; Lobus, N. V.; Shulga, N. A.

2017-12-01

It is shown that the reaction ability of metal cations of ore minerals in Fe-Mn crusts of the Marcus Wake Rise increases in the following manner: (Co2+ < Cu2+ < Ni2+) < (Mg2+ < Mn2+ < K+ ≈ Ca2+ ≈ Na+). The composition of the exchange complex of the ore minerals is constant and includes these metal cations. Ca2+ and Na+ are major contributors to the exchange capacity of the ore minerals. The capacity of the ore minerals by cations of alkali and base metals is 0.43-0.60 and 2.08-2.70 mg-equiv/g, respectively. The exchange capacity of the ore minerals by cations of base metals increases linearly with the increase in the MnO2 content of the crust and does not depend on the geographical locations of the Marcus Wake guyots.

Geospace Plasma Dynamics Laboratory Annual Task Report (FY11)

DTIC Science & Technology

2012-03-01

Site Contractors: Nagendra Singh, Ph.D., Physicist , 0.5 MY Neil Grossbard, M.S., Mathematician , 0.7 MY Visitors: Publications: Articles in...PhD Project Manager Division Chief, RVB This report is published in the interest of scientific and technical...Annual Task Report (FY11) 5c. PROGRAM ELEMENT NUMBER 61102F 6. AUTHOR(S) 5d. PROJECT NUMBER 2311 Daniel Ober 5e. TASK NUMBER

Installation Restoration Program. Phase II - Confirmation/Quantification. Stage 1 for American Lake Garden Tract, Washington.

DTIC Science & Technology

1985-12-20

Kalles . 1976. Evaporation rates of methylene chloride, chloroform, 1,1,1-trichloroethane, trichloroethylene, tetrachoroethylene, and other chlorinated...State University (1969) M.S., Geology, University of Washington ( 1971 ) . . Ph.D., University of Washington (1979) " EXPERIENCE 1984 to Date Senior...ducted environmental assessments for Pacific Northwest construc- tion projects. L- 1971 Project Geologist, SEREM of Alaska (BRGM-France). Responsibil

The BADER Consortium

DTIC Science & Technology

2014-10-01

neuromusculoskeletal injury o Determining factors that predict development and successful treatment of osteoarthritis, osteoporosis, low back pain , or other... students . The abstract highlights the collaborative work of the BADER-NICHD and potential to expand this model of collaborative work to other non-federal...regular contact with Drs. Dingwell and Wilken to complete on-going manuscripts.  Dr. McLagan and Ms. Mandy Salinas (U. Texas Ph.D. Student , hired Sept

Fresh Ideas, Perspectives, and Protocols Associated with Forest Inventory and Analysis Surveys: Graduate Reports, 1974 to July 2001

Treesearch

Victor A. Rudis

2003-01-01

Graduate M.S. theses and Ph.D. dissertations were searched to provide a body of information associated with the U.S. Department of Agriculture, Forest Service, Forest Inventory and Analysis (FIA) database. Authors' abstracts were included if available in electronic form and published since 1974. Novel technical and nontraditional FIA data uses, as well as the...

20 years of graduate optics education at the University of New Mexico

NASA Astrophysics Data System (ADS)

Osiński, Marek; Jungling, Kenneth C.; Sheik-Bahae, Mansoor; Prasad, Sudhakar; McIver, John K.; Guenther, Arthur H.

2003-10-01

The year 2003 marks the 20th anniversary of introducing interdisciplinary graduate optics education at the University of New Mexico. The Ph.D. program in Optical Sciences has produced over 75 graduates. A new M.S. program in Optical Science and Engineering, introduced in Fall 2002, is rapidly gaining popularity. This paper reviews both programs, focusing on their unique features.

What I Think I May Have Learned--Reflections on 50 Years of Teaching: An Interview with Michael Wertheimer

ERIC Educational Resources Information Center

Michael, Kurt D.

2006-01-01

Kurt Michael is an associate professor in the Department of Psychology at Appalachian State University (ASU) where he teaches history and systems of psychology, abnormal psychology, child psychopathology, and interventions for children and adolescents. He received his BA (cum laude) from the University of Colorado at Boulder and his MS and PhD in…

Ensuring a Safe Technological Revolution

DTIC Science & Technology

2016-12-01

Defense AT&L: November-December 2016 14 Ensuring a Safe Technological Revolution William E. Frazier, Ph.D. n Elizabeth L. McMichael n Jennifer...for 5 years, working on nonferrous welding and AM and has an M.S. in Mechanical Engineering from the University of Maryland, Baltimore County. I n...has acceptable proper- ties. A “certified” part can perform properly in its operating environment . The conventional qualification/certification

Studies of the Processing of Single Words Using Positron Tomographic Measures of Cerebral Blood Flow Change.

DTIC Science & Technology

1987-01-01

BLOOD FLOW CHANGE Steven E. Petersen, Peter T. Fox, Michael I. Posner, Marcus Raichle McDonnell Center for Studies of Higher Brain Function...Single Words Using Positron Emission Tomographic Measurements of Cerebral Blood Flow Change *= ’I PERSONAL AUTHOR(S) * Petersen, Steven E. 13a. TYPE OF...CHANGE Steven E. Petersen, Peter T. Fox, Michael I. Posner, Marcus E. Raichle INTRODUCTION Language is an essential characteristic of the human

Fatigue Testing of AA7050-T7451 with Various Corrosion Prevention Surface Treatments

DTIC Science & Technology

2013-06-01

UNCLASSIFIED Authors Marcus McDonald Air Vehicles Division Marcus McDonald initially spent 3 years working in the oil & gas, steel and...treatments: caustic degreasing, de-oxidising or anodising. The pits in the anodised coupons were larger than the pits caused by the pre-IVD etching...those fatigue cracks that grew from them spent less time in growing whilst they were small, because the crack started at what was a larger effective

Effects of Strong Local Sporadic E on ELF Propagation.

DTIC Science & Technology

1978-08-15

Huygens diffraction model (e.g., Marcuse , 1972). The model is similar to that used by Crombie. Unlike Crombie’s work however , the Fresnel approximation...40. Marcuse , D., “Light transmission optics ,” Van Nostrand Reinhold Co., New York , 1972. Papper t , R. A. & Moler , W. F., “A theoretica’ study of...ATTN Donald Dubbert O1 CY ATTN Herbert Rend University of IllinoisDepartment of Electrical Engineering Develco Urbana , IL 61803 530 Logue Avenue O2CY

First-principles calculation of photo-induced electron transfer rate constants in phthalocyanine-C60 organic photovoltaic materials: Beyond Marcus theory

NASA Astrophysics Data System (ADS)

Lee, Myeong H.; Dunietz, Barry D.; Geva, Eitan

2014-03-01

Classical Marcus theory is commonly adopted in solvent-mediated charge transfer (CT) process to obtain the CT rate constant, but it can become questionable when the intramolecular vibrational modes dominate the CT process as in OPV devices because Marcus theory treats these modes classically and therefore nuclear tunneling is not accounted for. We present a computational scheme to obtain the electron transfer rate constant beyond classical Marcus theory. Within this approach, the nuclear vibrational modes are treated quantum-mechanically and a short-time approximation is avoided. Ab initio calculations are used to obtain the basic parameters needed for calculating the electron transfer rate constant. We apply our methodology to phthalocyanine(H2PC)-C60 organic photovoltaic system where one C60 acceptor and one or two H2PC donors are included to model the donor-acceptor interface configuration. We obtain the electron transfer and recombination rate constants for all accessible charge transfer (CT) states, from which the CT exciton dynamics is determined by employing a master equation. The role of higher lying excited states in CT exciton dynamics is discussed. This work is pursued as part of the Center for Solar and Thermal Energy Conversion, an Energy Frontier Research Center funded by the US Department of Energy Office of Science, Office of Basic Energy Sciences under 390 Award No. DE-SC0000957.

How to Compute Electron Ionization Mass Spectra from First Principles.

PubMed

Bauer, Christoph Alexander; Grimme, Stefan

2016-06-02

The prediction of electron ionization (EI) mass spectra (MS) from first principles has been a major challenge for quantum chemistry (QC). The unimolecular reaction space grows rapidly with increasing molecular size. On the one hand, statistical models like Eyring's quasi-equilibrium theory and Rice-Ramsperger-Kassel-Marcus theory have provided valuable insight, and some predictions and quantitative results can be obtained from such calculations. On the other hand, molecular dynamics-based methods are able to explore automatically the energetically available regions of phase space and thus yield reaction paths in an unbiased way. We describe in this feature article the status of both methodologies in relation to mass spectrometry for small to medium sized molecules. We further present results obtained with the QCEIMS program developed in our laboratory. Our method, which incorporates stochastic and dynamic elements, has been a significant step toward the reliable routine calculation of EI mass spectra.

Implications of Marcus-Hush theory for steady-state heterogeneous electron transfer at an inlaid disk electrode.

PubMed

Feldberg, Stephen W

2010-06-15

For an outer-sphere heterogeneous electron transfer, Ox + e = Red, between an electrode and a redox couple, the Butler-Volmer formalism predicts that the operative heterogeneous rate constant, k(red) (cm s(-1)) for reduction (or k(ox) for oxidation) increases without limit as an exponential function of -alpha (E - E(0)) for reduction (or (1 - alpha)(E - E(0)) for oxidation), where E is the applied electrode potential, alpha (~1/2) is the transfer coefficient and E(0) is the formal potential. The Marcus-Hush formalism, as exposited by Chidsey (Chidsey, C. E. D. Science 1991, 215, 919), predicts that the value of k(red) or k(ox) limits at sufficiently large values of -(E - E(0)) or (E - E(0)). The steady-state currents at an inlaid disk electrode obtained for a redox species in solution were computed using both formalisms with the Oldham-Zoski approximation (Oldham, K. B.; Zoski, C. G. J. Electroanal. Chem. 1988, 256, 11). Significant differences are noted for the two formalisms. When k(0)r(0)/D is sufficiently small (k(0) is the standard rate constant, r(0) is the radius of the disk electrode, and D is the diffusion coefficient of the redox species), the Marcus-Hush formalism effects a limiting current that can be significantly smaller than the mass transport limited current. This is easily explained in terms of the limiting values of k(red) and k(ox) predicted by the Marcus-Hush formalism. The experimental conditions that must be met to effect significant differences in behavior are discussed; experimental conditions that effect virtually identical behavior are also discussed. As a caveat for experimentalists, applications of the Butler-Volmer formalism to systems that are more properly described using the Marcus-Hush formalism are shown to yield incorrect values of k(0) and meaningless values of alpha, which serves only as a fitting parameter.

Femtomolar Ln(III) affinity in peptide-based ligands containing unnatural chelating amino acids.

PubMed

Niedźwiecka, Agnieszka; Cisnetti, Federico; Lebrun, Colette; Delangle, Pascale

2012-05-07

The incorporation of unnatural chelating amino acids in short peptide sequences leads to lanthanide-binding peptides with a higher stability than sequences built exclusively from natural residues. In particular, the hexadentate peptide P(22), which incorporates two unnatural amino acids Ada(2) with aminodiacetate chelating arms, showed picomolar affinity for Tb(3+). To design peptides with higher denticity, expected to show higher affinity for Ln(3+), we synthesized the novel unnatural amino acid Ed3a(2) which carries an ethylenediamine triacetate side-chain and affords a pentadentate coordination site. The synthesis of the derivative Fmoc-Ed3a(2)(tBu)(3)-OH, with appropriate protecting groups for direct use in the solid phase peptide synthesis (Fmoc strategy), is described. The two high denticity peptides P(HD2) (Ac-Trp-Ed3a(2)-Pro-Gly-Ada(2)-Gly-NH(2)) and P(HD5) (Ac-Trp-Ada(2)-Pro-Gly-Ed3a(2)-Gly-NH(2)) led to octadentate Tb(3+) complexes with femtomolar stability in water. The position of the high denticity amino acid Ed3a(2) in the hexapeptide sequence appears to be critical for the control of the metal complex speciation. Whereas P(HD5) promotes the formation of polymetallic species in excess of Ln(3+), P(HD2) forms exclusively the mononuclear complex. The octadentate coordination of Tb(3+) by both P(HD) leads to total dehydration of the metal ion in the mononuclear complexes with long luminescence lifetimes (>2 ms). Hence, we demonstrated that unnatural amino acids carrying polyaminocarboxylate side-chains are interesting building blocks to design high affinity Ln-binding peptides. In particular the novel peptide P(HD2) forms a unique octadentate Tb(3+) complex with femtomolar stability in water and an improvement of the luminescence properties with respect to the trisaquo TbP(22) complex by a factor of 4.

STS-89 M.S. Andrew Thomas, Ph.D., participates in TCDT

NASA Technical Reports Server (NTRS)

1998-01-01

STS-89 Mission Specialist Andrew Thomas, Ph.D. gets ready to drive an M-113 armored personnel carrier as part of Terminal Countdown Demonstration Test (TCDT) activities. The TCDT is held at KSC prior to each Space Shuttle flight to provide crews with an opportunity to participate in simulated countdown activities. Standing inside the M-113 is Dr. Thomas while George Hoggard, a training officer with KSC Fire Services, sits atop the vehicle. The STS-89 mission will be the eighth docking of the Space Shuttle with the Russian Space Station Mir. After docking, Dr. Thomas will transfer to the space station, succeeding David Wolf, M.D., who will return to Earth aboard Endeavour. Dr. Thomas will live and work on Mir until June. STS-89 is scheduled for a Jan. 22 liftoff at 9:48 p.m.

Measuring Readiness in the Operational Reserve

DTIC Science & Technology

2014-06-13

annual medical and dental requirements, failure to conduct individual and collective training requirements, pregnancy , or any other disqualifier for...members Barry M. Stentiford, Ph.D.; MG William D. R. Waff, D.Min.; and Russell G. Conrad, M.S. for their guidance, assistance , and advice. Thanks to the...personnel and staff of Fort Leavenworth’s Combined Arms Research Library for assistance in researching sources. I would also like to thank Venita A

Hemorrhage Control for Major Traumatic Vascular Injuries

DTIC Science & Technology

2015-10-01

Human Subjects Protection Scientist, at 301-619-9268/karen.m.eaton.ctr@mail.mil. SHARON A. EVANS, PhD, CIP Deputy Director, Human Research... CIP Deputy Director, Human Research Protection Office Office of Research Protections US Army Medical Research and Materiel Command Note: The...debra.depaul.ctr@mail.mil; the POC for the USAMRMC ORP HRPO review is the undersigned at 301-619-7801. 25 ANDREA J. KLINE, MS, CIP Director

USAF/SCEEE Summer Faculty Research Program (1982). Management Report.

DTIC Science & Technology

1982-10-01

Patrick J. Sweeney, Ph.D., P.E. Mary Doddy, M.S. ABSTRACT This dynamic simulation computer model demonstrates the affects of C-forces upon the eyeball...Assistant Professor Specialty: Numerical Modeling and University of Lowell Computer Simulation of Mathematics Department Geophysical Problems Lowell...Problems And Promises 25 Modeling And Tracking Saccadic Dr. John D. Enderle Eye Movements 26 Dynamic Response Of Doubly Curved Dr. Fernando E. Fagundo

Senior Leader Perspective on the Air Force Nuclear Enterprise: Todays Issues and the Future

DTIC Science & Technology

2016-09-15

SENIOR LEADER PERSPECTIVE ON THE AIR FORCE NUCLEAR ENTERPRISE: TODAY’S ISSUES AND THE FUTURE GRADUATE RESEARCH PAPER Matthew D. Boone...States. AFIT-ENS-MS-16-S-028 SENIOR LEADER PERSPECTIVE ON THE AIR FORCE NUCLEAR ENTERPRISE: TODAY’S ISSUES AND THE FUTURE GRADUATE... ISSUES AND THE FUTURE Matthew D. Boone, BS, MA Major, USAF Committee Membership: Robert E. Overstreet, Lt Col, USAF, PhD

Implement Family Member Assessment Component in the Millennium Cohort Study

DTIC Science & Technology

2010-10-01

Hospital , Camp Pendleton, CA Tyler C. Smith, MS, PhD, DoD Center for Deployment Health Research, NHRC, San Diego CA Col Timothy S. Wells, USAF, BSC, Air...physical health, relationship quality, deployment/ reunion , and service utilization. In addition, data will be linked to medical records collected...Laboratory, Wright-Patterson Air Force Base, OH; and Margaret Ryan from the Naval Hospital Camp Pendleton, Camp Pendleton, CA. Additionally, the

The PTSD Practitioner Registry: An Innovative Tracking, Dissemination, and Support Tool for Providers in Military and Nonmilitary Settings

DTIC Science & Technology

2016-10-01

Watertown, MA 02472 REPORT DATE: October 2016 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick...Rebekah Zincavage Project Role: Qualitative Researcher Nearest person month worked: 1 Contribution to Project: Ms. Zincavage developed the...Military and Nonmilitary Settings PRINCIPAL INVESTIGATOR: Raymond C. Rosen, PhD CONTRACTING ORGANIZATION: New Englad Research Instituites, Inc

Army Sustainment. Volume 43, Issue 6, November-December 2011

DTIC Science & Technology

2011-12-01

challenges. The first challenge was being noti- fied before the CAR that the BSA would need to move to shorten the lines of communication ( LOC ) while the...aDMiniStration froM Saint leo univerSity, an M.S. in SeconDary eDucation froM olD DoMinion univerSity, anD a ph.D. in eDucation aDMin- iStration anD leaDerShip

Marcus Bell-Shaped Electron Transfer Kinetics Observed in an Arrhenius Plot.

PubMed

Waskasi, Morteza M; Kodis, Gerdenis; Moore, Ana L; Moore, Thomas A; Gust, Devens; Matyushov, Dmitry V

2016-07-27

The Marcus theory of electron transfer predicts a bell-shaped dependence of the reaction rate on the reaction free energy. The top of the "inverted parabola" corresponds to zero activation barrier when the electron-transfer reorganization energy and the reaction free energy add up to zero. Although this point has traditionally been reached by altering the chemical structures of donors and acceptors, the theory suggests that it can also be reached by varying other parameters of the system including temperature. We find here dramatic evidence of this phenomenon from experiments on a fullerene-porphyrin dyad. Following photoinduced electron transfer, the rate of charge recombination shows a bell-shaped dependence on the inverse temperature, first increasing with cooling and then decreasing at still lower temperatures. This non-Arrhenius rate law is a result of a strong, approximately hyperbolic temperature variation of the reorganization energy and the reaction free energy. Our results provide potentially the cleanest confirmation of the Marcus energy gap law so far since no modification of the chemical structure is involved.

Charge transfer kinetics at the solid-solid interface in porous electrodes

NASA Astrophysics Data System (ADS)

Bai, Peng; Bazant, Martin Z.

2014-04-01

Interfacial charge transfer is widely assumed to obey the Butler-Volmer kinetics. For certain liquid-solid interfaces, the Marcus-Hush-Chidsey theory is more accurate and predictive, but it has not been applied to porous electrodes. Here we report a simple method to extract the charge transfer rates in carbon-coated LiFePO4 porous electrodes from chronoamperometry experiments, obtaining curved Tafel plots that contradict the Butler-Volmer equation but fit the Marcus-Hush-Chidsey prediction over a range of temperatures. The fitted reorganization energy matches the Born solvation energy for electron transfer from carbon to the iron redox site. The kinetics are thus limited by electron transfer at the solid-solid (carbon-LixFePO4) interface rather than by ion transfer at the liquid-solid interface, as previously assumed. The proposed experimental method generalizes Chidsey’s method for phase-transforming particles and porous electrodes, and the results show the need to incorporate Marcus kinetics in modelling batteries and other electrochemical systems.

Access to enhanced differences in Marcus-Hush and Butler-Volmer electron transfer theories by systematic analysis of higher order AC harmonics.

PubMed

Stevenson, Gareth P; Baker, Ruth E; Kennedy, Gareth F; Bond, Alan M; Gavaghan, David J; Gillow, Kathryn

2013-02-14

The potential-dependences of the rate constants associated with heterogeneous electron transfer predicted by the empirically based Butler-Volmer and fundamentally based Marcus-Hush formalisms are well documented for dc cyclic voltammetry. However, differences are often subtle, so, presumably on the basis of simplicity, the Butler-Volmer method is generally employed in theoretical-experimental comparisons. In this study, the ability of Large Amplitude Fourier Transform AC Cyclic Voltammetry to distinguish the difference in behaviour predicted by the two formalisms has been investigated. The focus of this investigation is on the difference in the profiles of the first to sixth harmonics, which are readily accessible when a large amplitude of the applied ac potential is employed. In particular, it is demonstrated that systematic analysis of the higher order harmonic responses in suitable kinetic regimes provides predicted deviations of Marcus-Hush from Butler-Volmer behaviour to be established from a single experiment under conditions where the background charging current is minimal.

STS-89 M.S. Dunbar and Sharipov chat under the orbiter after landing

NASA Technical Reports Server (NTRS)

1998-01-01

STS-89 Mission Specialist Bonnie Dunbar, Ph.D., at left, discusses the mission with Mission Specialist Salizhan Sharipov of the Russian Space Agency under the orbiter Endeavour after it landed on Runway 15 at KSCs Shuttle Landing Facility Jan. 31. The 89th Space Shuttle mission was the 42nd (and 13th consecutive) landing of the orbiter at KSC, and STS-89 was the eighth of nine planned dockings of the orbiter with the Russian Space Station Mir. STS-89 Mission Specialist Andrew Thomas, Ph.D., succeeded NASA astronaut and Mir 24 crew member David Wolf, M.D., who was on the Russian space station since late September 1997. Dr. Wolf returned to Earth on Endeavour with the remainder of the STS-89 crew, including Commander Terrence Wilcutt; Pilot Joe Edwards Jr.; and Mission Specialists James Reilly, Ph.D.; Michael Anderson; Dr. Dunbar; and Sharipov. Dr. Thomas is scheduled to remain on Mir until the STS-91 Shuttle mission returns in June 1998. In addition to the docking and crew exchange, STS-89 included the transfer of science, logistical equipment and supplies between the two orbiting spacecrafts.

STS-103 M.S. Steven Smith during TCDT activities

NASA Technical Reports Server (NTRS)

1999-01-01

STS-103 Mission Specialist Steven L. Smith gets ready to practice driving a small armored personnel carrier that is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.), (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who are with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

STS-96 M.S. Dan Barry checks equipment during a CEIT

NASA Technical Reports Server (NTRS)

1999-01-01

In the Orbiter Processing Facility bay 1, STS-96 Mission Specialist Daniel Barry, M.D., Ph.D., looks at one of the foot restraints used for extravehicular activity, or space walks. The STS-96 crew is at KSC to take part in a Crew Equipment Interface Test. The other crew members are Commander Kent V. Rominger, Pilot Rick Douglas Husband, and Mission Specialists Ellen Ochoa (Ph.D.), Tamara E. Jernigan (Ph.D.), Julie Payette and Valery Ivanovich Tokarev. Payette represents the Canadian Space Agency and Tokarev the Russian Space Agency. The primary payload of STS- 96 is the SPACEHAB Double Module. In addition, the Space Shuttle will carry unpressurized cargo such as the external Russian cargo crane known as STRELA; the Spacehab Oceaneering Space System Box (SHOSS), which is a logistics items carrier; and an ORU Transfer Device (OTD), a U.S.-built crane that will be stowed on the station for use during future ISS assembly missions. These cargo items will be stowed on the International Cargo Carrier, fitted inside the payload bay behind the SPACEHAB module. STS-96 is targeted for launch on May 24 from Launch Pad 39B.

Charge-transfer mechanism for electrophilic aromatic nitration and nitrosation via the convergence of (ab initio) molecular-orbital and Marcus-Hush theories with experiments.

PubMed

Gwaltney, Steven R; Rosokha, Sergiy V; Head-Gordon, Martin; Kochi, Jay K

2003-03-19

The highly disparate rates of aromatic nitrosation and nitration, despite the very similar (electrophilic) properties of the active species: NO(+) and NO(2)(+) in Chart 1, are quantitatively reconciled. First, the thorough mappings of the potential-energy surfaces by high level (ab initio) molecular-orbital methodologies involving extensive coupled-cluster CCSD(T)/6-31G optimizations establish the intervention of two reactive intermediates in nitration (Figure 8) but only one in nitrosation (Figure 7). Second, the same distinctive topologies involving double and single potential-energy minima (Figures 6 and 5) also emerge from the semiquantitative application of the Marcus-Hush theory to the transient spectral data. Such a striking convergence from quite different theoretical approaches indicates that the molecular-orbital and Marcus-Hush (potential-energy) surfaces are conceptually interchangeable. In the resultant charge-transfer mechanism, the bimolecular interactions of arene donors with both NO(+) and NO(2)(+) spontaneously lead (barrierless) to pi-complexes in which electron transfer is concurrent with complexation. Such a pi-complex in nitration is rapidly converted to the sigma-complex, whereas this Wheland adduct in nitrosation merely represents a high energy (transition-state) structure. Marcus-Hush analysis thus demonstrates how the strongly differentiated (arene) reactivities toward NO(+) and NO(2)(+) can actually be exploited in the quantitative development of a single coherent (electron-transfer) mechanism for both aromatic nitrosation and nitration.

On the gas phase fragmentation of protonated uracil: a statistical perspective.

PubMed

Rossich Molina, Estefanía; Salpin, Jean-Yves; Spezia, Riccardo; Martínez-Núñez, Emilio

2016-06-01

The potential energy surface of protonated uracil has been explored by an automated transition state search procedure, resulting in the finding of 1398 stationary points and 751 reactive channels, which can be categorized into isomerizations between pairs of isomers, unimolecular fragmentations and bimolecular reactions. The use of statistical Rice-Ramsperger-Kassel-Marcus (RRKM) theory and Kinetic Monte Carlo (KMC) simulations allowed us to determine the relative abundances of each fragmentation channel as a function of the ion's internal energy. The KMC/RRKM product abundances are compared with novel mass spectrometry (MS) experiments in the collision energy range 1-6 eV. To facilitate the comparison between theory and experiments, further dynamics simulations are carried out to determine the fraction of collision energy converted into the ion's internal energy. The KMC simulations show that the major fragmentation channels are isocyanic acid and ammonia losses, in good agreement with experiments. The third predominant channel is water loss according to both theory and experiments, although the abundance obtained in the KMC simulations is very low, suggesting that non-statistical dynamics might play an important role in this channel. Isocyanic acid (HNCOH(+)) is also an important product in the KMC simulations, although its abundance is only significant at internal energies not accessible in the MS experiments.

Microdesigning of Lightweight/High Strength Ceramic Materials.

DTIC Science & Technology

1987-08-30

if applicable) AFSSR NC Grant No. AFOSR-83-0375 8c. ADDRESS( Cft , State. and ZIP Code) 10 SOURCE OF FUNDING NUMBERS Bd.40PROGRAMO IPROJECT I TASK...The Adsorption of Pohmethacrvfic Acid from Solut.on.- Ph.D. Thesis . Polytechnic Institute of Brooklyn (1961). I5. R. J. Hunter. Zeta Potential in...Hasz. ’Surface Reactions and Electrical Double Layer Properties of Ceramic Ox. ides in Aqueous Solution,* M.S. Thesis . Massachusetts Institute of

Novel Therapeutic Targets to Treat Social Behavior Deficits in Autism and Related Disorders

DTIC Science & Technology

2016-06-01

INVESTIGATOR: Georgianna G. Gould, M.S., Ph.D. CONTRACTING ORGANIZATION: The University of Texas Health Science Center at San Antonio San Antonio, TX...PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER The University of Texas Health Science Center at San Antonio 7703...Collaborating Consultants are at the University of Texas Health Science Center Facility, and all experiments will be performed on-site, so there were

A 10-Year Review of the Food Science Summer Scholars Program: A Model for Research Training and for Recruiting Undergraduate Students into Graduate Programs and Careers in Food Science

ERIC Educational Resources Information Center

Roberts, Angela J.; Robbins, Janette; McLandsborough, Lynne; Wiedmann, Martin

2010-01-01

A pressing problem facing regulatory agencies, academia, and the food industry is a shortage of qualified food science graduates, particularly those with advanced degrees (that is, M.S. or Ph.D.). In 2000, the Cornell Institute of Food Science established the annual Food Science Summer Scholars Program as an experiential summer research program…

Experimental and Theoretical Basis for a Closed-Form Spectral BRDF Model

DTIC Science & Technology

2015-09-17

EXPERIMENTAL AND THEORETICAL BASIS FOR A CLOSED-FORM SPECTRAL BRDF MODEL DISSERTATION Samuel D. Butler, Major, USAF AFIT-ENP-DS-15-S-021 DEPARTMENT...SPECTRAL BRDF MODEL DISSERTATION Presented to the Faculty Graduate School of Engineering and Management Air Force Institute of Technology Air University Air...FOR A CLOSED-FORM SPECTRAL BRDF MODEL DISSERTATION Samuel D. Butler, BS, MS Major, USAF Committee Membership: Michael A. Marciniak, PhD Chairman Kevin

Analysis of Pacific Enroute Structure in Support of C-5M Super Galaxy

DTIC Science & Technology

2015-06-19

Christopher J. Keller, BS, MS Major, USAF Lt Col Adam Reiman , PhD Research Advisor AFIT-ENS-GRP-15-J-011 Abstract...Adam Reiman , for his guidance and support throughout the course of this research effort. His insights and experience were certainly appreciated. I...reasonable to expect a payload of approximately 160,000 pounds. Figure 1. Pallet weight distribution ( Reiman , et al., 2013:6) This research will

An Interview with Matthew P. Greving, PhD. Interview by Vicki Glaser.

PubMed

Greving, Matthew P

2011-10-01

Matthew P. Greving is Chief Scientific Officer at Nextval Inc., a company founded in early 2010 that has developed a discovery platform called MassInsight™.. He received his PhD in Biochemistry from Arizona State University, and prior to that he spent nearly 7 years working as a software engineer. This experience in solving complex computational problems fueled his interest in developing technologies and algorithms related to acquisition and analysis of high-dimensional biochemical data. To address the existing problems associated with label-based microarray readouts, he beganwork on a technique for label-free mass spectrometry (MS) microarray readout compatible with both matrix-assisted laser/desorption ionization (MALDI) and matrix-free nanostructure initiator mass spectrometry (NIMS). This is the core of Nextval’s MassInsight technology, which utilizes picoliter noncontact deposition of high-density arrays on mass-readout substrates along with computational algorithms for high-dimensional data processingand reduction.

Jian Receives 2009 F. L. Scarf Award

NASA Astrophysics Data System (ADS)

2010-03-01

Lan Jian has been awarded the AGU F. L. Scarf Award, given annually to recent Ph.D recipients for outstanding dissertation research that contributes directly to solar planetary sciences. Jian's thesis is entitled “Radial evolution of large-scale solar wind structures.” She was formally presented with the award at the Space Physics and Aeronomy section dinner during the 2009 AGU Fall Meeting, held 14-18 December in San Francisco, Calif. Lan Jian received her B.S. in geophysics from University of Science and Technology of China in 2003. She received her M.S. and Ph.D. degrees in geophysics and space physics, under the supervision of Christopher T. Russell, at University of California, Los Angeles in 2006 and 2008, respectively. Her research interests include various structures in the solar wind, their origin and evolution, and their effect on the space environment of planets.

Vithanage Receives 2009 Natural Hazards Focus Group Award for Graduate Research

NASA Astrophysics Data System (ADS)

2010-04-01

Meththika Vithanage has been awarded the Natural Hazards Focus Group Award for Graduate Research, given annually to recent Ph.D. recipients for outstanding contributions to natural hazards research. Vithanage’s thesis is entitled “Effect of tsunami on coastal aquifers: Field studies and tank experiments.” She was formally presented with the award at the Natural Hazards Focus Group reception during the 2009 AGU Fall Meeting, held 14-18 December in San Francisco, Calif. Vithanage received her B.S. in natural resources from Sabaragamuwa University of Sri Lanka in 2002 and an M.S. in environmental science from the University of Peradeniya, Sri Lanka, in 2005. In 2009, she attained a Ph.D. in hydrogeology under the supervision of Karsten Jensen and Peter Engesgaard in the Department of Geology and Geography at University of Copenhagen, Denmark. Her research interests include groundwater flow modeling, density-dependent flow and solute transport modeling, and water quality analysis.

Unified interpretation of exciplex formation and marcus electron transfer on the basis of two-dimensional free energy surfaces.

PubMed

Murata, Shigeo; Tachiya, M

2007-09-27

The mechanism of exciplex formation proposed in a previous paper has been refined to show how exciplex formation and Marcus electron transfer (ET) in fluorescence quenching are related to each other. This was done by making simple calculations of the free energies of the initial (DA*) and final (D+A-) states of ET. First it was shown that the decrease in D-A distance can induce intermolecular ET even in nonpolar solvents where solvent orientational polarization is absent, and that it leads to exciplex formation. This is consistent with experimental results that exciplex is most often observed in nonpolar solvents. The calculation was then extended to ET in polar solvents where the free energies are functions of both D-A distance and solvent orientational polarization. This enabled us to discuss both exciplex formation and Marcus ET in the same D-A pair and solvent on the basis of 2-dimensional free energy surfaces. The surfaces contain more information about the rates of these reactions, the mechanism of fluorescence quenching by ET, etc., than simple reaction schemes. By changing the parameters such as the free energy change of reaction, solvent dielectric constants, etc., one can construct the free energy surfaces for various systems. The effects of free energy change of reaction and of solvent polarity on the mechanism and relative importance of exciplex formation and Marcus ET in fluorescence quenching can be well explained. The free energy surface will also be useful for discussion of other phenomena related to ET reactions.

Comparison of the Marcus and Pekar partitions in the context of non-equilibrium, polarizable-continuum solvation models

DOE Office of Scientific and Technical Information (OSTI.GOV)

You, Zhi-Qiang; Herbert, John M., E-mail: herbert@chemistry.ohio-state.edu; Mewes, Jan-Michael

2015-11-28

The Marcus and Pekar partitions are common, alternative models to describe the non-equilibrium dielectric polarization response that accompanies instantaneous perturbation of a solute embedded in a dielectric continuum. Examples of such a perturbation include vertical electronic excitation and vertical ionization of a solution-phase molecule. Here, we provide a general derivation of the accompanying polarization response, for a quantum-mechanical solute described within the framework of a polarizable continuum model (PCM) of electrostatic solvation. Although the non-equilibrium free energy is formally equivalent within the two partitions, albeit partitioned differently into “fast” versus “slow” polarization contributions, discretization of the PCM integral equations failsmore » to preserve certain symmetries contained in these equations (except in the case of the conductor-like models or when the solute cavity is spherical), leading to alternative, non-equivalent matrix equations. Unlike the total equilibrium solvation energy, however, which can differ dramatically between different formulations, we demonstrate that the equivalence of the Marcus and Pekar partitions for the non-equilibrium solvation correction is preserved to high accuracy. Differences in vertical excitation and ionization energies are <0.2 eV (and often <0.01 eV), even for systems specifically selected to afford a large polarization response. Numerical results therefore support the interchangeability of the Marcus and Pekar partitions, but also caution against relying too much on the fast PCM charges for interpretive value, as these charges differ greatly between the two partitions, especially in polar solvents.« less

MD studies of electron transfer at ambient and elevated pressures

NASA Astrophysics Data System (ADS)

Giles, Alex; Spooner, Jacob; Weinberg, Noham

2013-06-01

The effect of pressure on the rate constants of outer-sphere electron transfer reactions has often been described using the Marcus-Hush theory. This theory agrees well with experiment when internal reorganization of the ionic system is negligible, however it does not offer a recipe for calculation of the effects that result from significant solute restructuring. We have recently developed a molecular dynamics technique that accurately describes structural dependence of molecular volumes in non-polar and weakly polar systems. We are now extending this approach to the case of highly polar ionic systems where both solvent and solute restructuring components are important. For this purpose we construct pressure-dependent two-dimensional surfaces for electron transfer reactions in coordinate system composed of interionic distance and Marcus-type solvent polarization coordinate, and use these surfaces to describe pressure effects on reaction kinetics. R.A. Marcus. J. Chem. Phys. 24, 966 (1956); 24, 979 (1956); 26, 867 (1957). Discuss. Faraday Soc. 29, 21 (1960). Faraday Discuss. Chem. Soc. 74, 7 (1982); N.S. Hush. Trans. Faraday Soc. 57, 557 (1961).

SS Edgar M. Queeny collision with the Liberian S/T Corinthos, Marcus Hook, Pennsylvania, 31 January 1975. Marine casualty report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1977-10-27

At 0029, on January 31, 1975, the U.S. Registered tankship SS EDGAR M. QUEENY, laden with chemical and petroleum products, was maneuvering into Marcus Hook channel of the Delaware River in Pennsylvania, when it collided with the Liberian tanker S/T CORINTHOS which was moored and discharging a bulk cargo of crude oil at the British Petroleum Company dock. The port anchor of the QUEENY slightly penetrated the port side plating of the CORINTHOS at an angle of about 39 deg. into one or more of the wing cargo tanks, which were being pumped and were approximately half full. Almost immediately,more » a series of increasingly intense explosions began in the CORINTHOS, and the vessel was engulfed in flames. Twenty-six persons were killed or are missing and 11 were injured in this accident. The QUEENY suffered minor damage but the CORINTHOS was destroyed. The Delaware River was polluted by oil about Marcus Hook. Property damage was estimated to be $20 million.« less

Compound 49b Reduces Inflammatory Markers and Apoptosis after Ocular Blast Injury

DTIC Science & Technology

2018-02-01

Vanessa M. Morales-Tirado MS, PhD CONTRACTING ORGANIZATION: University of Tennessee Health Science Center Memphis, TN 38163 REPORT DATE: February...which are critical for the visual output from the eye to the brain in health and ocular injury. 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17...February 2018 15Aug2012 - 14Aug2015 Dr. Vanessa Morales vmorale1@uthsc.edu University of Tennessee Health Science Center Memphis, TN 38163 W81XWH

Acoustic Studies of New Materials: Quasicrystals, Low-Loss Glasses, and High Tc Superconductors

DTIC Science & Technology

1991-12-18

Progress Report, 1989 2. Tania Slawecki, M.S. Thesis Measuring fourth sound in silica aerogel 3. Chang Yu, Ph.D. Thesis A high Q resonant photoacoustic...Pennsylvania State University The Graduate School Department of Physics Measuring Fourth Sound in Silica Aerogel A Thesis in Physics by Tania Maria...Slawecki Submitted in Partial Fulfillment of the Requirements for the Degree of Master of Science December 1989 Abstract Measuring Fourth Sound in Silica

Army Advanced Concept Technology Demonstrations - The Inside Story

DTIC Science & Technology

1997-08-01

has M.S. sors suitable for field use are expected to be * What are the costs vs . benefits and/or and Ph.D. degrees in applied math- available in...scales and in different Proving languages. Implementation Forces (IFOR) Ground. established a Mine Action Center ( MAC ) to deal with the mine incidents and...minefield data problems. Initially, the data had to be manually tracked and posted. Working with personnel in the MAC , the ACTF sponsored work leading

The Center of Excellence for Hypersonics Training and Research at the University of Texas at Austin

NASA Technical Reports Server (NTRS)

Dolling, David S.

1993-01-01

Over the period of this grant (1986-92), 23 graduate students were supported by the Center and received education and training in hypersonics through MS and Ph.D. programs. An additional 8 Ph.D. candidates and 2 MS candidates, with their own fellowship support, were attracted to The University of Texas and were recruited into the hypersonics program because of the Center. Their research, supervised by the 10 faculty involved in the Center, resulted in approximately 50 publications and presentations in journals and at national and international technical conferences. To provide broad-based training, a new hypersonics curriculum was created, enabling students to take 8 core classes in theoretical, computational, and experimental hypersonics, and other option classes over a two to four semester period. The Center also developed an active continuing education program. The Hypersonics Short Course was taught 3 times, twice in the USA and once in Europe. Approximately 300 persons were attracted to hear lectures by more than 25 of the leading experts in the field. In addition, a hypersonic aerodynamics short course was offered through AIAA, as well as short courses on computational fluid dynamics (CFD) and advanced CFD. The existence of the Center also enabled faculty to leverage a substantial volume of additional funds from other agencies, for research and graduate student training. Overall, this was a highly successful and highly visible program.

Experimental Neutrino Physics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilkes, Richard Jeffrey

The University of Washington (UW) HEP neutrino group performed experimental research on the physics of neutrinos, using the capabilities offered by the T2K Experiment and the Super-Kamiokande Neutrino Observatory. The UW group included senior investigator R. J. Wilkes, two PhD students, four MS degree students, and a research engineer, all of whom are members of the international scientific collaborations for T2K and Super-Kamiokande. During the period of support, within T2K we pursued new precision studies sensitive to new physics, going beyond the limits of current measurements of the fundamental neutrino oscillation parameters (mass differences and mixing angles). We began effortsmore » to measure (or significantly determine the absence of) 1 the CP-violating phase parameter δCP and determine the neutrino mass hierarchy. Using the Super-Kamiokande (SK) detector we pursued newly increased precision in measurement of neutrino oscillation parameters with atmospheric neutrinos, and extended the current reach in searches for proton decay, in addition to running the most sensitive supernova watch instrument [Scholberg 2012], performing other astrophysical neutrino studies, and analyzing beam-induced events from T2K. Overall, the research addressed central questions in the field of particle physics. It included the training of graduate students (both PhD and professional MS degree students), and postdoctoral researchers. Undergraduate students also participated as laboratory assistants.« less

Electrochemical reduction of carbon fluorine bond in 4-fluorobenzonitrile Mechanistic analysis employing Marcus Hush quadratic activation-driving force relation

NASA Astrophysics Data System (ADS)

Muthukrishnan, A.; Sangaranarayanan, M. V.

2007-10-01

The reduction of carbon-fluorine bond in 4-fluorobenzonitrile in acetonitrile as the solvent, is analyzed using convolution potential sweep voltammetry and the dependence of the transfer coefficient on potential is investigated within the framework of Marcus-Hush quadratic activation-driving force theory. The validity of stepwise mechanism is inferred from solvent reorganization energy estimates as well as bond length calculations using B3LYP/6-31g(d) method. A novel method of estimating the standard reduction potential of the 4-fluorobenzonitrile in acetonitrile is proposed.

Communication: Standard surface hopping predicts incorrect scaling for Marcus' golden-rule rate: The decoherence problem cannot be ignored

NASA Astrophysics Data System (ADS)

Landry, Brian R.; Subotnik, Joseph E.

2011-11-01

We evaluate the accuracy of Tully's surface hopping algorithm for the spin-boson model for the case of a small diabatic coupling parameter (V). We calculate the transition rates between diabatic surfaces, and we compare our results to the expected Marcus rates. We show that standard surface hopping yields an incorrect scaling with diabatic coupling (linear in V), which we demonstrate is due to an incorrect treatment of decoherence. By modifying standard surface hopping to include decoherence events, we recover the correct scaling (˜V2).

A Probabilistic Approach for Reliability and Life Prediction of Electronics in Drilling and Evaluation Tools

DTIC Science & Technology

2014-12-23

A Probabilistic Approach for Reliability and Life Prediction of Electronics in Drilling and Evaluation Tools Amit A. Kale 1 , Katrina Carter...dielectric breakdown has been Amit Kale et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0...160.doi 10.1016/S0167- 4730(00)00005-9. BIOGRAPHIES Amit A. Kale was born in Bhopal, India on October 25 1978. He earned PhD in 2005 and MS in

Autonomous Micro Air Vehicles with Hovering Capabilities

DTIC Science & Technology

2009-02-01

One MS thesis by Bharani Malladi was completed in December of 2007 and one PhD thesis by Bill Silin is in progress and expected by May 2009...transition from slow flight to hover flight in a way that can authorize building R Figure 1. Low-speed wind tunnel (left) and the 5-component micro...January 2007. 3Henry, J. I., Schwartz, D. R ., Soukup, M. A., Altman, A., “Design, Construction, and Testing of a Folding-Wing, Tube- Launched Micro Air

The Relevance and Optimal Structure of the Military in Jamaica in the Current and Emerging Geo-Security Environment

DTIC Science & Technology

2003-06-06

Graduate Degree Programs Philip J. Brookes, Ph.D. The opinions and conclusions expressed herein are those of the student author and do not necessarily...hope I will be forgiven if I only mention a few: Prof. Ernest Evans, Dr. Philip Brookes, Mrs. Helen Davis, Mrs. Jacqueline Goulbourne, Ms. Mary Glaser...the Caribbean. Jamaica has had a number of confrontations, particularly with Honduras, regarding illegal fishing at its Pedro and Morant Cays. This

The REMR Bulletin. News from the Repair, Evaluation, Maintenance, and Rehabilitation Research Program. Volume 11. Number 2

DTIC Science & Technology

1994-07-01

civil engineering from Ohio State University. For the past 10 circulating Flow," Technical Report HL-91-14, years , Schneider has worked in the field...and a Ph.D. in burg, MS. general engineering from Mississippi State University. For the past 14 years , Bernard has worked in the field of...of fields, the art of flood figxhitsinghas changed little over the past century. Duringthe Flood, several innovative expedient flood fight-ing

Configuration Synthesis and Efficient Motion Programming of Robot Manipulators

DTIC Science & Technology

1991-03-15

Gupta and Ma 90- Robotica 8:81-84]. When a set of discrete stations are specified along a robot task path, it becomes necessary to find a related...velocity Jacobian relations for the manipulator [Singh 87-MS Thesis][Gupta and Singh 89- Robotica 7:159-1641 and [Cheng 89-PhD Thesis][Cheng and Gupta...1987; Robotica 7:159-164, 1989 (revised). K. C. Gupta, "Kinematics of a Robot with Continuous Roll Wrist," IEEE J. Robotics and Automation 4(4):440-443

James Roy Barcus 1930-1988

NASA Astrophysics Data System (ADS)

colleagues; Brown, R. R.; Goldberg, R. A.; Rosenberg, T. J.; Patel, V. L.

James Roy Barcus, professor of physics at the University of Denver, Colo., died January 3, 1988, at his home in Denver after a long battle with lung cancer.Barcus was born in Kansas City, Mo., on September 30, 1930. He served in the U.S. Navy before enrolling as an undergraduate at the University of New Mexico, where he obtained his B.S., M.S., and Ph.D. degrees. His doctoral research was on extensive air showers of cosmic radiation, under J. R. Green.

Traumatic Brain Injury Screening: Preliminary Findings in a US Army Brigade Combat Team

DTIC Science & Technology

2009-01-01

Screening: Preliminary Findings in a US Army Brigade Combat Team Heidi Terrio, MD, MPH; Lisa A. Brenner, PhD; Brian J. Ivins, MS; John M. Cho, MD; Katherine...Sheila Saliman and Lisa Betthauser is greatly appreciated. Corresponding author: Heidi Terrio, MD, MPH, 1853 O’Connell Blvd, Bldg 1042, Room 107, Fort...more mild TBI symptoms among injured soldiers with and without TBI (n = 1208)∗,† Parameter Adjusted 95% CI adjusted Variable estimate (β) SE β Wald P

Integrating an Intelligent Tutoring System for TAOs with Second Life

DTIC Science & Technology

2010-12-01

SL) and interacts with a number of computer -controlled objects that take on the roles of the TAO’s teammates. TAOs rely on the same mechanism to...projects that utilize both game and simulation technology for training. He joined Stottler Henke in the fall of 2000 and holds a Ph.D. in computer science...including implementing tutors in multiuser worlds. He has been at Stottler Henke since 2005 and has a MS in computer science from Stanford University

Studies on a middle Pennsylvanian compression-impression flora from the overburden of the Herrin (No. 6) coal at Carterville, Illinois

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gastaldo, R.A.

Titles and authors of Ph.D dissertations and M.S. theses are listed as completed or near completion in the following areas of study related to coal: botany (10), chemistry (10), community development (1), economics (1), electrical science and systems engineering (1), forestry (7), geography (2), geology (23), health education (2), mathematics (1), zoology (24), mining engineering (9), plant and soil science (4), political science (2), and thermal and environmental engineering (3).

STS-89 M.S. Sharipov, his wife, and M.S. Thomas, at the SLF

NASA Technical Reports Server (NTRS)

1998-01-01

STS-89 Mission Specialist Salizhan Sharipov of the Russian Space Agency, at left, poses with his wife, Nadezhda Sharipova, and Mission Specialist Andrew Thomas, Ph.D., at right, shortly after arrival at the KSC Shuttle Landing Facility. The eight STS-89 crew members flew into KSC from Johnson Space Center as final preparations are under way toward the scheduled liftoff on Jan. 22 of the Space Shuttle Endeavour on the eighth mission to dock with the Russian Space Station Mir. After docking, Dr. Thomas will transfer to the space station, succeeding David Wolf, M.D., who will return to Earth aboard Endeavour. Dr. Thomas will live and work on Mir until June. STS-89 is scheduled for a Jan. 22 liftoff at 9:48 p.m. EST.

"Abnormal" salt and solvent effects on anion/cation electron-transfer reactions: an interpretation based on Marcus-Hush treatment.

PubMed

Garcia-Fernandez, E; Prado-Gotor, R; Sanchez, F

2005-08-11

Salt and solvent effects on the kinetics of the reactions [Fe(CN)6]3- + [Ru(NH3)5pz](2+) right arrow over left arrow [Fe(CN)6]4- + [Ru(NH3)5pz]3+ (pz = pyrazine) have been studied through T-jump measurements. The forward and reverse reactions show different behaviors: "abnormal" salt and solvent effects in the first case and normal effects in the second one. These facts imply an asymmetric behavior of anion/cation reactions depending on the charge of the oxidant. The results can be rationalized by using the Marcus-Hush treatment for electron-transfer reactions.

Effect of viscosity on photoinduced electron transfer reaction: An observation of the Marcus inverted region in homogeneous solvents

NASA Astrophysics Data System (ADS)

Saini, Rajesh Kumar; Kuchlyan, Jagannath; Sarkar, Nilmoni

2016-09-01

The viscosity effect of homogeneous solvents on the dynamics of photoinduced electron transfer (PET) reaction among the coumarins and N,N-dimethylaniline (DMA) is investigated using steady-state and time-resolved fluorescence spectroscopy. A bell shape Marcus inversion in the ET rates has been detected in the plot of ET rate constant (kq) with free energy change (ΔG0) in viscous solvents decanol and EG, but it is not observed in DMSO like low viscous solvent. We have also reported that there is no complex formation between the coumarin dye and DMA molecule by using fluorescence correlation spectroscopy.

Thermodynamic and spectroscopic speciation to explain the blackening process of hematite formed by atmospheric SO2 impact: the case of Marcus Lucretius House (Pompeii).

PubMed

Maguregui, Maite; Knuutinen, Ulla; Martínez-Arkarazo, Irantzu; Castro, Kepa; Madariaga, Juan M

2011-05-01

After many decades exposed to a polluted environment, in some areas of Marcus Lucretius House, there are clear signs that plasters and hematite pigments are suffering deterioration. In the exhaustive analysis of the black layer covering the red pigment hematite it was possible to identify magnetite (Fe(3)O(4)) as responsible for the black colour, which always appears in combination with gypsum. Thermodynamic modelling stated that the presence of gypsum as well as the transformation of hematite into magnetite is a consequence of the attack of atmospheric SO(2).

"East side story": on being an epidemiologist in the former USSR: an interview with Marcus Klingberg.

PubMed

Klingberg, Marcus

2006-01-01

Marcus Klingberg was born on 7 October 1918, in Warsaw, Poland, into a Hasidic, rabbinical family. After the Nazi invasion of Poland, he escaped to the USSR where he trained and worked as an epidemiologist from 1939 to 1945. For 35 years after the war, he continued his professional work in Israel. The harsh conditions within the Soviet Union during World War II provided a challenging setting for epidemiologic work-a setting that has remained largely hidden from Western view. In this interview, Klingberg describes his work as an epidemiologist in the USSR and his subsequent encounter with Western epidemiology.

Delaware River water quality Bristol to Marcus Hook, Pennsylvania, August 1949 to December 1963

USGS Publications Warehouse

Keighton, Walter B.

1965-01-01

During the 14-year period from August 1949 to July 1963, the U.S. Geological Survey, in cooperation with the city of Philadelphia, collected samples of river water once each month in the 43-mile reach of the Delaware River from Bristol to Marcus Hook, Pa., and daily at Trenton, 10 miles upstream from Bristol. This part of the Delaware is an estuary into which salt water is brought by tides; fresh water flows into the estuary at Trenton, NJ, and farther downstream from the Schuylkill River and other tributaries of the Delaware. In March, April, and May, when fresh-water flow is high, the average concentration of dissolved solids in the water at Bristol was 76 ppm (parts per million), and at Marcus Hook 112 PPM In August and September, streamflow is lower, and the average concentration of dissolved solids increased to 117 PPM at Bristol and 804 PPM at Marcus Hook. Major salinity invasions of the Delaware River occurred in 1949, 1953, 1954, 1957, and 1963. In each of these years the fresh-water flow into the tidal river at Trenton was low during the period from July to October. The greatest dissolved-solids concentrations in these monthly samples were 160 PPM at Bristol and 4,000 PPM at Marcus Hook. At times the dissolved-oxygen concentration of the river water has become dangerously low, especially in that reach of the river between Wharton Street and League Island. At the Benjamin Franklin Bridge, one-third of the samples of river water were less than 30 percent saturated with oxygen; however, no trend, either for better or for worse, was apparent during the 14-year period. It is useful now to summarize these monthly analyses for the period 1949-63 even though a much more detailed description of water quality in this reach of the estuary will soon become available through the use of recording instrumental conditions. This compendium of water-quality data is useful as an explicit statement of water quality during the 14-year study period and is valuable for directing attention to water-quality problems for selecting instrument sites, and for making comparative studies with the more detailed information which is already being obtained with the aid of recording instruments.

STS-87 M.S. Doi and Chawla and P.S. Kadenyuk in slidewire basket

NASA Technical Reports Server (NTRS)

1997-01-01

The crew of the STS-87 mission, scheduled for launch Nov. 19 aboard the Space Shuttle Columbia from pad 39B at Kennedy Space Center (KSC), participates in the Terminal Countdown Demonstration Test (TCDT) at KSC. Testing a slide wire basket that is part of the pads emergency egress system are, from left, Mission Specialist Takao Doi, Ph.D., of the National Space Development Agency of Japan; Payload Specialist Leonid Kadenyuk of the National Space Agency of Ukraine (NSAU); and Mission Specialist Kalpana Chawla, Ph.D. The TCDT is held at KSC prior to each Space Shuttle flight providing the crew of each mission opportunities to participate in simulated countdown activities. The TCDT ends with a mock launch countdown culminating in a simulated main engine cut-off. The crew also spends time undergoing emergency egress training exercises at the pad and has an opportunity to view and inspect the payloads in the orbiter's payload bay.

Joint MS Degree Program between the Korea University of Technology and Education and the University of Kansas

NASA Astrophysics Data System (ADS)

Dougherty, R. L.; Kim, Kwang Su

This paper provides an overview of the Joint MS Degree Program between Korea University of Technology and Education’ s (KUT) Mechatronics Department and Kansas University’ s (KU) Mechanical Engineering Department. Discussions were initiated in early 2005 which resulted in a formal agreement being approved by both parties in mid-2007. The Joint MS Degree Program is composed of 30 semester credit hours, equally split between the two universities, with the actual degree being awarded by the institution at which the thesis work is performed. Issues addressed during the development of this Joint MS Program included: joint versus dual degrees, institutional acceptance of the transfer of fifteen hours of credit for an MS degree, different admissions requirements and procedures for the two institutions, financial support of the students, faculty advisors at each institution, Graduate Directors at each institution, transcript acknowledgement of the Joint Degree, residency requirements, English speaking requirements/abilities, thesis publication allowances/requirements, and time zone differences for virtual meetings. These issues have been addressed, and the Joint MS Degree Program is functioning with a small number of students having taken advantage of the opportunity since the Program’ s inception. Future considerations are: growing the number of students in the Program, expansion to other Departments besides KU-Mechanical Engineering and KUTMechatronics, including other universities in the Program, expansion to a Joint PhD Degree Program, and stronger funding resources.

Applied Geophysics Opportunities in the Petroleum Industry

NASA Astrophysics Data System (ADS)

Olgaard, D. L.; Tikku, A.; Roberts, J. C.; Martinez, A.

2012-12-01

Meeting the increasing global demand for energy over the next several decades presents daunting challenges to engineers and scientists, including geoscientists of all disciplines. Many opportunities exist for geophysicists to find and produce oil and gas in a safe, environmentally responsible and affordable manner. Successful oil and gas exploration involves a 'Plates to Pores' approach that integrates multi-scale data from satellites, marine and land seismic and non-seismic field surveys, lab experiments, and even electron microscopy. The petroleum industry is at the forefront of using high performance computing to develop innovative methods to process and analyze large volumes of seismic data and perform realistic numerical modeling, such as finite element fluid flow and rock deformation simulations. Challenging and rewarding jobs in exploration, production and research exist for students with BS/BA, MS and PhD degrees. Geophysics students interested in careers in the petroleum industry should have a broad foundation in science, math and fundamental geosciences at the BS/BA level, as well as mastery of the scientific method, usually gained through thesis work at MS and PhD levels. Field geology or geophysics experience is also valuable. Other personal attributes typical for geoscientists to be successful in industry include a passion for solving complex geoscience problems, the flexibility to work on a variety of assignments throughout a career and skills such as teamwork, communication, integration and leadership. In this presentation we will give examples of research, exploration and production opportunities for geophysicists in petroleum companies and compare and contrast careers in academia vs. industry.

Numerical analysis and modeling of atmospheric phenomena

NASA Technical Reports Server (NTRS)

Stone, Peter H.

1994-01-01

For the past 22 years Grant NGR 22-009-727 has been supporting research in the Center for Meteorology and Physical Oceanography (and its predecessors) in a wide variety of diagnostic and modeling studies of atmospheric and ocean phenomena. Professor Jule Charney was the initial Principal Investigator. Professor Peter Stone joined him as co-Principal Investigator in 1975 and became the sole Principal Investigator in 1981. During its lifetime the Grant has supported in whole or in part 11 Master's theses, 14 Ph.D. theses, and 45 papers published in refereed scientific journals. All of these theses and papers (with bibliographic references) are listed below. All but one of the theses were used to fulfill the requirements for MIT (Massachusetts Institute of Technology) degrees and are available from the MIT libraries. The one exception is F. Chen's Ph.D. thesis which was for a Harvard degree and is available from the Harvard libraries. In addition to the work described in the citations listed below, the Grant has supported Research Assistant Amy Solomon during the past two years to carry out a study of how baroclinic adjustment is affected by vertical resolution, vertical temperature structure, and dissipation. Ms. Solomon plans to use this project for her Ph.D. thesis. Support for this project will continue under NASA Grant NAG 5-2490, 'The Factors Controlling Poleward Heat Transport in Climate Models.'

Fourth Bionanotox and Applications Research Conference, 2009

NASA Astrophysics Data System (ADS)

Camp, Judy

2010-04-01

"Anticipating the future" seemed the common challenge for scientists attending the 4th BioNanoTox and Applications Research Conference in Little Rock, AR, October 21-22, 2009. Over 50 participants in multi-disciplines such as biology, chemistry, physics, medicine, medical diagnostics, computer science and informatics, nanotechnology, toxicology, and pharmaceutical science gathered to share their research data. From topics on water and food resources to space exploration to conservation to understanding biological activities and using instruments and computers that process enormous data, participants shared research approaches from different fields to find common themes in this integrated field. Presentations aimed at preventing the harmful effects of scientific discoveries to animals, humans, plants, and environment; at controlling infections; and at optimizing health care. The conference included addresses from Thomas Flammang, PhD, of the Food and Drug Administration, National Center for Toxicological Research in Jefferson, AR; Little Rock City Mayor Mark Stodola; and two keynote speakers. Keynote lectures by Danuta Leszczynska, PhD, from the Department of Civil and Environmental Engineering, Interdisciplinary Nanotoxicity Center, in Jackson, MS, and by Keith Cowan, PhD, from the Institute for Environmental Biotechnology in Grahamstown, South Africa, highlighted current trends and future challenges of nanoparticle research and of bioprocess technologies. Additionally, 25 graduate and undergraduate students presented research posters, resulting in valuable discussion among the varied participants; three student projects were selected for awards.

IBP's Four-Prong Approach for Broadening Participation in the STEM Community

NASA Astrophysics Data System (ADS)

Ricciardi, L.; Fauver, A.; Johnson, A.; Detrick, L.; Siegfried, D.; Thomas, S.; Valaitis, S.

2013-12-01

The goal of the Institute for Broadening Participation (IBP) is to increase diversity in the Science, Technology, Engineering and Mathematics (STEM) workforce. As a freestanding non-profit dedicated to this work IBP is uniquely positioned to provide resources to faculty and students that individual institutions and disciplinary based programs cannot. Through its initial work with the NSF Integrative Graduate Education and Research Traineeship (IGERT), Research Experiences for Undergraduates (REU), and Alliance for Graduate Education and the Professoriate (AGEP) programs, IBP developed a four-pronged approach open to all members of the STEM community nationally for addressing the problem of underrepresentation: Synthesizing information - compiling and translating best practices into materials and resources accessible and useful to a broad national audience; Creating and maintaining strategic web resources - making information on programs, best practices, and references easily available to a wide audience including students, faculty, and administrators; Extensive face-to-face and virtual outreach - drawing constituents to the resources available via IBP that support students and faculty through the entire STEM pathway; and Catalyzing partnerships - cultivating a community of practice and culture of diversity, to reduce isolation among diversity practitioners, and to increase information sharing. IBP is also home to several successful initiatives that use both virtual and face-to-face components to bring together underrepresented students with established underrepresented and other scientists in academia, government and industry. These connections provide underrepresented students with supportive mentoring, networking opportunities, and professional skill development contributing to an overall improved retention rate of underrepresented students majoring in STEM degrees. IBP's initiatives include the NASA One Stop Shopping Initiative (NASA OSSI), Pathways to Ocean Science, Pathways to Engineering, and the Minorities Striving and Pursuing Higher Degrees of Success (MS PHD'S) Professional Development program in Earth System Science (ESS). NASA OSSI recruits and facilitates student engagement in NASA student education and employment opportunities. Pathways to Ocean Science connects and supports underrepresented students with REU programs in Ocean Sciences and serves as a resource for REU program directors. Pathways to Engineering synthesized mentoring resources into an online mentoring manual for underrepresented STEM students that has been extensively vetted by mentoring experts throughout the country. MS PHD'S, an award-winning professional development program for underrepresented students, focuses on increasing the retention rate of underrepresented students receiving advanced degrees in ESS. As of August 2013, 213 students have participated in the program. 67 of those students are currently enrolled in a PhD. program. Another 47 have completed their PhD and are actively engaged in the ESS workforce.

Eros and Thanatos: A Nondualistic Interpretation: The Dynamic of Drives in Personal and Civilizational Development From Freud to Marcuse.

PubMed

Kli, Maria

2018-02-01

The Freudian theory of drives gave prominence to the idea that there is an inherent principle of entropy, a tendency for dissolution of life, referred to as the Death drive, or Thanatos. Freud recognized a counterbalancing tendency for sustaining life, known as the Life drive, or Eros. The psychoanalytical expounding of the struggle of Eros and Thanatos in the context of the civilizational process sparked the philosophical critique of civilization. Although Freud tended to consider repression an indispensable dimension of this process, the author proposes in this paper that Herbert Marcuse's political critique took Freud's metapsychology further philosophically, suggesting a nondualistic interpretation of Freud's position.

Undergraduate Training in the Epidemiology of Prostate Cancer with Focus on Genetics of Disease Progression and Quality of Life

DTIC Science & Technology

2014-08-01

Brown’s Paper entitled “Pharmacogenomics and Prostate Cancer ” focused on the impact of cytochrome P450 genes such as CYP2C9, CYP 2D6, CYP 1A1 and CYP...Podophyllotoxins). Ms. Cobb’s paper focused on the pharmacogenetics of breast cancer and on the role of phase 1 and phase 2 hepatic enzymes on pharmacological... Cancer with Focus on Genetics of Disease Progression and Quality of Life PRINCIPAL INVESTIGATOR: Emanuela Taioli, MD, PhD CONTRACTING

The Challenge and the Promise: Strengthening the Force, Preventing Suicide and Saving Lives. Final Report of the Department of Defense Task Force on the Prevention of Suicide by Members of the Armed Forces

DTIC Science & Technology

2010-08-01

Sergeant Major Ronald Green USMC Major General Philip Volpe, DO, MC USA Marjan Ghahramounlou Holloway, PhD Commander Aaron...and one civilian member serving as co-chairs for the group. Major General Philip Volpe, initially the Deputy Commander of Joint Task Force, National...and representation from each Service. Major General Philip Volpe was appointed as the military co-chair, and Ms. Bonnie Carroll was elected as the

Chemical characteristics of Delaware River water, Trenton, New Jersey, to Marcus Hook, Pennsylvania

USGS Publications Warehouse

Durfor, Charles N.; Keighton, Walter B.

1954-01-01

This progress report gives the results of an investigation of the quality of water in the Delaware River from Trenton, N. J. to Marcus Hook, Pa., for the period August 1949 to December 1952. The Delaware River is the principal source of water for the many industries and municipal water supplies along this reach of the river and both industries and municipalities use it for the disposal of their wastes. Consequently, a study of the quality of the water and variations in the quality caused by changes in streamflow, tidal effects, pollution and other factors is important to the many users. In both New Jersey and Pennsylvania steps are being taken to abate pollution, thus it is of more than passing interest to measure the effects of waste treatment on the quality of the Delaware River water. At average or higher rates of streamflow the mineral content of the water increases slightly from Trenton to Marcus Hook. There is little variation in the concentration of dissolved minerals from bank to bank or from top to bottom of the river. At times of protracted low rates of flow the effect of ocean water mixing with the river water may be noted as far upstream as Philadelphia. At such times the salinity is often greater near the bottom of the river than near the top. The increase in chloride concentration upstream from Philadelphia is small compared to the rapid increase downstream from Philadelphia. Temperatures of offshore water vary with the season, but on a given day are substantially uniform throughout the reach of the river from Trenton to Marcus Hook. The water contains less dissolved oxygen as it flows downstream indicating that oxygen is being consumed by oxidizable matter. From Philadelphia downstream there are periods, especially in late summer, when the dissolved oxygen is barely sufficient to meet the oxygen demands of the pollution load.

The gatemon: a transmon with a voltage-variable superconductor-semiconductor junction

NASA Astrophysics Data System (ADS)

Petersson, Karl

We have developed a superconducting transmon qubit with a semiconductor-based Josephson junction element. The junction is made from an InAs nanowire with in situ molecular beam epitaxy-grown superconducting Al contacts. This gate-controlled transmon, or gatemon, allows simple tuning of the qubit transition frequency using a gate voltage to vary the density of carriers in the semiconductor region. In the first generations of devices we have measured coherence times up to ~10 μs. These coherence times, combined with stable qubit operation, permit single qubit rotations with fidelities of ~99.5 % for all gates including voltage-controlled Z rotations. Towards multi-qubit operation we have also implemented a two qubit voltage-controlled cPhase gate. In contrast to flux-tuned transmons, voltage-tunable gatemons may simplify the task of scaling to multi-qubit circuits and enable new means of control for many qubit architectures. In collaboration with T.W. Larsen, L. Casparis, M.S. Olsen, F. Kuemmeth, T.S. Jespersen, P. Krogstrup, J. Nygard and C.M. Marcus. Research was supported by Microsoft Project Q, Danish National Research Foundation and a Marie Curie Fellowship.

Predicting Accurate Electronic Excitation Transfer Rates via Marcus Theory with Boys or Edmiston-Ruedenberg Localized Diabatization †

DOE Office of Scientific and Technical Information (OSTI.GOV)

Subotnik, Joseph E.; Vura-Weis, Josh; Sodt, Alex J.

We model the triplet-triplet energy-transfer experiments from the Closs group [Closs, G. L.; et al. J. Am. Chem. Soc. 1988, 110, 2652.] using a combination of Marcus theory and either Boys or Edmiston-Ruedenberg localized diabatization, and we show that relative and absolute rates of electronic excitation transfer may be computed successfully. For the case where both the donor and acceptor occupy equatorial positions on a rigid cyclohexane bridge, we find βcalc = 2.8 per C-C bond, compared with the experimental value βexp = 2.6. This work highlights the power of using localized diabatization methods as a tool for modeling nonequilibriummore » processes.« less

Predicting Accurate Electronic Excitation Transfer Rates via Marcus Theory with Boys or Edmiston-Ruedenberg Localized Diabatization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Subotnik, Joseph E.; Vura-Weis, Josh; Sodt, Alex J.

We model the triplet-triplet energy-transfer experiments from the Closs group [Closs, G. L.; et al. J. Am. Chem. Soc. 1988, 110, 2652.] using a combination of Marcus theory and either Boys or Edmiston-Ruedenberg localized diabatization, and we show that relative and absolute rates of electronic excitation transfer may be computed successfully. For the case where both the donor and acceptor occupy equatorial positions on a rigid cyclohexane bridge, we find β calc = 2.8 per C-C bond, compared with the experimental value β exp = 2.6. This work highlights the power of using localized diabatization methods as a tool formore » modeling nonequilibrium processes.« less

On the relation between Marcus theory and ultrafast spectroscopy of solvation kinetics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roy, Santanu; Galib, Mirza; Schenter, Gregory K.

The phenomena of solvent exchange control the process of solvating ions, protons, and charged molecules. Building upon our extension of Marcus’ philosophy of electron transfer, here we provide a new perspective of ultrafast solvent exchange mechanism around ions measurable by two-dimensional infrared (2DIR) spectroscopy. In this theory, solvent rearrangement drives an ion-bound water to an activated state of higher coordination number, triggering ion-water separation that leads to the solvent-bound state of the water molecule. This ion-bound to solvent-bound transition rate for a BF 4 --water system is then computed using ab initio molecular dynamics and Marcus theory, and is foundmore » to be in excellent agreement with the 2DIR measurement.« less

On the relation between Marcus theory and ultrafast spectroscopy of solvation kinetics

DOE PAGES

Roy, Santanu; Galib, Mirza; Schenter, Gregory K.; ...

2017-12-24

The phenomena of solvent exchange control the process of solvating ions, protons, and charged molecules. Building upon our extension of Marcus’ philosophy of electron transfer, here we provide a new perspective of ultrafast solvent exchange mechanism around ions measurable by two-dimensional infrared (2DIR) spectroscopy. In this theory, solvent rearrangement drives an ion-bound water to an activated state of higher coordination number, triggering ion-water separation that leads to the solvent-bound state of the water molecule. This ion-bound to solvent-bound transition rate for a BF 4 --water system is then computed using ab initio molecular dynamics and Marcus theory, and is foundmore » to be in excellent agreement with the 2DIR measurement.« less

On the relation between Marcus theory and ultrafast spectroscopy of solvation kinetics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roy, Santanu; Galib, Mirza; Schenter, Gregory K.

The phenomena of solvent exchange control the process of solvating ions, protons, and charged molecules. Building upon our extension of Marcus’ philosophy of electron transfer, we provide a new perspective of ultrafast solvent exchange mechanism around ions measurable by two-dimensional infrared (2DIR) spectroscopy. In this theory, solvent rearrangement drives an ion-bound water to an activated state of higher coordination number, triggering ion-water separation that leads to the solvent-bound state of the water molecule. This ion-bound to solvent-bound transition rate for a BF4- water system is computed using ab initio molecular dynamics and Marcus theory, and is found to be inmore » excellent agreement with the 2DIR measurement.« less

Dynamics of a Chlorophyll Dimer in Collective and Local Thermal Environments

DOE PAGES

Merkli, M.; Berman, Gennady Petrovich; Sayre, Richard Thomas; ...

2016-01-30

Here we present a theoretical analysis of exciton transfer and decoherence effects in a photosynthetic dimer interacting with collective (correlated) and local (uncorrelated) protein-solvent environments. Our approach is based on the framework of the spin-boson model. We derive explicitly the thermal relaxation and decoherence rates of the exciton transfer process, valid for arbitrary temperatures and for arbitrary (in particular, large) interaction constants between the dimer and the environments. We establish a generalization of the Marcus formula, giving reaction rates for dimer levels possibly individually and asymmetrically coupled to environments. We identify rigorously parameter regimes for the validity of the generalizedmore » Marcus formula. The existence of long living quantum coherences at ambient temperatures emerges naturally from our approach.« less

Direct assays of radiation-induced DNA base lesions in mammalian cells: Technical progress report, July 1, 1986--December 1, 1988

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wheeler, K.T. Jr.

1988-01-01

Our cesium irradiator was installed in April 1987 and has the capability of irradiating DNA solutions, cells and animals at dose rates from >60 Gy/min to <10/sup /minus/2/ Gy/min. By early summer all of the dosimetry and set-ups were established to perform this research. In may 1987, Dr. Krystyna Lesiak left to return to the National Institutes of Health. However, she has remained a collaborator over the past 1/1/2/ years. She has synthesized a large lot of ..cap alpha..-deoxyadenosine, isolated a large batch of both the R and S isomer of cyclodeoxyadenosine and has capped the ..cap alpha..-deoxyadenonsine for usemore » in a DNA synthesizer that uses phosphoramidite chemistry. In November 1987, Dr. Andrzej Surowiec joined our unit as a Visiting Research Assistant Professor. Dr. Surowiec has a MS degree in electrical engineering and did his Ph.D. in Biophysics studying the conductivity of DNA in dilute solution. He has been performing the helix-coil transition experiments. In November 1987, Dr. Steven Swarts also joined our unit as a Postdoctoral Fellow. He received his Ph.D. from Oakland University under Dr. Michael Sevilla with whom we have a collaboration studying the induction of base damage in hydrated DNA. Dr. Swarts has a strong background in spectroscopy and, therefore, was a key individual for determination of the limitations of the HPLC assays and the establishment of a GC/MS capability equivalent to Dr. M. Dizdaroglu at the National Bureau of Standards. 9 refs., 1 tab.« less

Women Break an Engineering Barrier: While Other Engineering Disciplines Stumble, BME Represents a Success Story in Attracting American Women to a Male-Dominated Field.

PubMed

Gutierrez, Claudia; Paulosky, Meaghan; Aguinaldo, Angeline; Gerhart, Jackie

2017-01-01

While the field of engineering as a whole is largely male-dominated, biomedical engineering (BME) is one area poised to overturn this trend. Women in the United States were awarded only 20% of all engineering B.S. degrees in 2015; in BME, however, 40.9% of the degree recipients were women. This stands in stark contrast to the more traditional fields of mechanical and electrical engineering, where women were awarded just 13.2% and 12.5% of B.S. degrees, respectively. This trend toward more female participation in BME continues at both the M.S. and Ph.D. degree levels. In fact, in 2015, BME had the highest percentage of female engineering M.S. degree recipients in the United States of all engineering disciplines, according to the American Society for Engineering Education (Figure 1).

Synthesis, Microstructure and Properties of Nickel Aluminide Foams

NASA Technical Reports Server (NTRS)

Dunand, David C.

2003-01-01

Two Ph.D. students were involved in the project: Mr. Christopher Schuh (part-time, graduated in Spring 2001) and Ms. Andrea Hodge (full-time, graduated Summer 2002). One post-doctoral fellow, Dr. Heeman Choe, worked full-time on the project from July to December 2002. A new process to aluminize and chromize nickel foams was created. A kinetic aluminization model was developed. Creep testing was conducted on the foams. A finite-element model and a simplified analytical model for foam creep were produced. Four articles were written: one is published, two are accepted for publication, and one is in preparation. Ms. Hodge spent four months at NASA Glenn Research Center (9-12/2001 and 2-3/2002) under the supervision of Dr. Nathal. She conducted research on NiAl foam fabrication, mechanical testing and numerical modeling. She gave a talk at the ASM annual conference in November 2001 and presented her results at NASA in December 2001.

Oceanography and Geoscience Scholars at Texas A&M University Funded through the NSF S-STEM (Scholarships in Science, Technology, Engineering and Mathematics) Program

NASA Astrophysics Data System (ADS)

Richardson, M. J.; Gardner, W. D.

2016-02-01

Over the last seven years we have led the creation and implementation of the Oceanography and Geoscience Scholars programs at Texas A&M University. Through these programs we have been able to provide scholarship support for 92 undergraduates in Geosciences and 29 graduate students in Oceanography. Fifty-seven undergraduate scholars have graduated in Geosciences: 30 undergraduate students in Meteorology, 7 in Geology, and 20 in Environmental Geosciences. Two students have graduated in other STEM disciplines. Twenty-four students are in the process of completing their undergraduate degrees in STEM disciplines. Twenty-three students have graduated with MS or PhD degrees in Oceanography and five PhD students are completing their dissertations. As specified in the program solicitation all of the scholars are academically talented students with demonstrated financial need as defined by the FAFSA (Free Application for Federal Student Aid). We have endeavored to recruit students from underrepresented groups. One-third of the undergraduate scholars were from underrepresented groups; 28% of the graduate students. We will present the challenges and successes of these programs.

STS-93 MS Tognini tries on his helmet in the O&C Bldg.

NASA Technical Reports Server (NTRS)

1999-01-01

During launch and entry suit check in the Operations and Checkout Bldg, STS-93 Mission Specialist Michel Tognini of France, who represents the Centre National d'Etudes Spatiales (CNES), tries on his helmet. In preparation for their mission, the STS-93 crew are participating in Terminal Countdown Demonstration Test activities that also include equipment check and a launch-day dress rehearsal culminating with a simulated main engine cut-off. Others in the crew participating are Commander Eileen M. Collins, Pilot Jeffrey S. Ashby, and Mission Specialists Steven A. Hawley (Ph.D.) and Catherine G. Coleman (Ph.D.). Collins is the first woman to serve as a Shuttle commander. The primary mission of STS-93 is the release of the Chandra X-ray Observatory, which will allow scientists from around the world to obtain unprecedented X-ray images of exotic environments in space to help understand the structure and evolution of the universe. The targeted launch date for STS-93 is no earlier than July 20 at 12:36 a.m. EDT from Launch Pad 39B.

STS-93 MS Coleman takes in view from 195-foot level of launch pad

NASA Technical Reports Server (NTRS)

1999-01-01

At the 195-foot level of Launch Pad 39B, STS-93 Mission Specialist Catherine G. Coleman (Ph.D.) takes in the view. The STS-93 crew are at KSC to participate in a Terminal Countdown Demonstration Test, which familiarizes them with the mission, provides training in emergency exit from the orbiter and launch pad, and includes a launch-day dress rehearsal culminating with a simulated main engine cut-off. Other crew members are Commander Eileen M. Collins, Pilot Jeffrey S. Ashby, and Mission Specialists Steven A. Hawley (Ph.D.) and Michel Tognini of France, who represents the Centre National d'Etudes Spatiales (CNES). The primary mission of STS-93 is the release of the Chandra X-ray Observatory, which will allow scientists from around the world to obtain unprecedented X-ray images of exotic environments in space to help understand the structure and evolution of the universe. The targeted launch date for STS-93 is no earlier than July 20 at 12:36 a.m. EDT from Launch Pad 39B.

Structure and Dynamics of Solvent Landscapes in Charge-Transfer Reactions

NASA Astrophysics Data System (ADS)

Leite, Vitor B. Pereira

The dynamics of solvent polarization plays a major role in the control of charge transfer reactions. The success of Marcus theory describing the solvent influence via a single collective quadratic polarization coordinate has been remarkable. Onuchic and Wolynes have recently proposed (J. Chem Phys 98 (3) 2218, 1993) a simple model demonstrating how a many-dimensional-complex model composed by several dipole moments (representing solvent molecules or polar groups in proteins) can be reduced under the appropriate limits into the Marcus Model. This work presents a dynamical study of the same model, which is characterized by two parameters, an average dipole-dipole interaction as a term associated with the potential energy landscape roughness. It is shown why the effective potential, obtained using a thermodynamic approach, is appropriate for the dynamics of the system. At high temperatures, the system exhibits effective diffusive one-dimensional dynamics, where the Born-Marcus limit is recovered. At low temperatures, a glassy phase appears with a slow non-self-averaging dynamics. At intermediate temperatures, the concept of equivalent diffusion paths and polarization dependence effects are discussed. This approach is extended to treat more realistic solvent models. Real solvents are discussed in terms of simple parameters described above, and an analysis of how different regimes affect the rate of charge transfer is presented. Finally, these ideas are correlated to analogous problems in other areas.

Fine mapping of the genic male-sterile ms 1 gene in Capsicum annuum L.

PubMed

Jeong, Kyumi; Choi, Doil; Lee, Jundae

2018-01-01

The genomic region cosegregating with the genic male-sterile ms 1 gene of Capsicum annuum L. was delimited to a region of 869.9 kb on chromosome 5 through fine mapping analysis. A strong candidate gene, CA05g06780, a homolog of the Arabidopsis MALE STERILITY 1 gene that controls pollen development, was identified in this region. Genic male sterility caused by the ms 1 gene has been used for the economically efficient production of massive hybrid seeds in paprika (Capsicum annuum L.), a colored bell-type sweet pepper. Previously, a CAPS marker, PmsM1-CAPS, located about 2-3 cM from the ms 1 locus, was reported. In this study, we constructed a fine map near the ms 1 locus using high-resolution melting (HRM) markers in an F 2 population consisting of 1118 individual plants, which segregated into 867 male-fertile and 251 male-sterile plants. A total of 12 HRM markers linked to the ms 1 locus were developed from 53 primer sets targeting intraspecific SNPs derived by comparing genome-wide sequences obtained by next-generation resequencing analysis. Using this approach, we narrowed down the region cosegregating with the ms 1 gene to 869.9 kb of sequence. Gene prediction analysis revealed 11 open reading frames in this region. A strong candidate gene, CA05g06780, was identified; this gene is a homolog of the Arabidopsis MALE STERILITY 1 (MS1) gene, which encodes a PHD-type transcription factor that regulates pollen and tapetum development. Sequence comparison analysis suggested that the CA05g06780 gene is the strongest candidate for the ms 1 gene of paprika. To summarize, we developed a cosegregated marker, 32187928-HRM, for marker-assisted selection and identified a strong candidate for the ms 1 gene.

Understanding the mechanism of nanotube synthesis for controlled production of specific (n,m) structures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Resasco, Daniel E.

2010-02-11

This report shows the extensive research on the mechanism responsible for the formation of single walled carbon nanotubes in order to get control over their structural parameters (diameter and chirality). Catalyst formulations, pre-treatment conditions, and reaction conditions are described in detail as well as mechanisms to produce nanotubes structures of specific arrays (vertical forest, nanotube pillars). Applications of SWNT in different fields are also described in this report. In relation to this project five students have graduated (3 PhD and 2 MS) and 35 papers have been published.

Optical Nonlinearities in GaAs/GaAlAs Multiple Quantum Wells Fabricated by Metalorganic Chemical Vapor Deposition for Use in Optical Signal Processing.

DTIC Science & Technology

1987-12-01

larger energy separation of the terminal states. The spectra of the thicker wells show peaks due to transitions from the n=2 and n=3 electron states. The...are found in the theses of H. C. Lee (PhD) and M. Kawase (MS). Section III contains an invited paper submittted to Journal of Quantum Electronics ...steps are associated with the allowed energies of the "square well potential" and are a strong function of the dimensions of the well and the

Carrier mobility in double-helix DNA and RNA: A quantum chemistry study with Marcus-Hush theory.

PubMed

Wu, Tao; Sun, Lei; Shi, Qi; Deng, Kaiming; Deng, Weiqiao; Lu, Ruifeng

2016-12-21

Charge mobilities of six DNAs and RNAs have been computed using quantum chemistry calculation combined with the Marcus-Hush theory. Based on this simulation model, we obtained quite reasonable results when compared with the experiment, and the obtained charge mobility strongly depends on the molecular reorganization and electronic coupling. Besides, we find that hole mobilities are larger than electron mobilities no matter in DNAs or in RNAs, and the hole mobility of 2L8I can reach 1.09 × 10 -1 cm 2 V -1 s -1 which can be applied in the molecular wire. The findings also show that our theoretical model can be regarded as a promising candidate for screening DNA- and RNA-based molecular electronic devices.

A nonmonotonic dependence of standard rate constant on reorganization energy for heterogeneous electron transfer processes on electrode surface

NASA Astrophysics Data System (ADS)

Xu, Weilin; Li, Songtao; Zhou, Xiaochun; Xing, Wei; Huang, Mingyou; Lu, Tianhong; Liu, Changpeng

2006-05-01

In the present work a nonmonotonic dependence of standard rate constant (k0) on reorganization energy (λ) was discovered qualitatively from electron transfer (Marcus-Hush-Levich) theory for heterogeneous electron transfer processes on electrode surface. It was found that the nonmonotonic dependence of k0 on λ is another result, besides the disappearance of the famous Marcus inverted region, coming from the continuum of electronic states in electrode: with the increase of λ, the states for both Process I and Process II ET processes all vary from nonadiabatic to adiabatic state continuously, and the λ dependence of k0 for Process I is monotonic thoroughly, while for Process II on electrode surface the λ dependence of k0 could show a nonmonotonicity.

Carrier mobility in double-helix DNA and RNA: A quantum chemistry study with Marcus-Hush theory

NASA Astrophysics Data System (ADS)

Wu, Tao; Sun, Lei; Shi, Qi; Deng, Kaiming; Deng, Weiqiao; Lu, Ruifeng

2016-12-01

Charge mobilities of six DNAs and RNAs have been computed using quantum chemistry calculation combined with the Marcus-Hush theory. Based on this simulation model, we obtained quite reasonable results when compared with the experiment, and the obtained charge mobility strongly depends on the molecular reorganization and electronic coupling. Besides, we find that hole mobilities are larger than electron mobilities no matter in DNAs or in RNAs, and the hole mobility of 2L8I can reach 1.09 × 10-1 cm2 V-1 s-1 which can be applied in the molecular wire. The findings also show that our theoretical model can be regarded as a promising candidate for screening DNA- and RNA-based molecular electronic devices.

Asymmetric Marcus-Hush theory for voltammetry.

PubMed

Laborda, Eduardo; Henstridge, Martin C; Batchelor-McAuley, Christopher; Compton, Richard G

2013-06-21

The current state-of-the-art in modeling the rate of electron transfer between an electroactive species and an electrode is reviewed. Experimental studies show that neither the ubiquitous Butler-Volmer model nor the more modern symmetric Marcus-Hush model are able to satisfactorily reproduce the experimental voltammetry for both solution-phase and surface-bound redox couples. These experimental deviations indicate the need for revision of the simplifying approximations used in the above models. Within this context, models encompassing asymmetry are considered which include different vibrational and solvation force constants for the electroactive species. The assumption of non-adiabatic electron transfer is also examined. These refinements have provided more satisfactory models of the electron transfer process and they enable us to gain more information about the microscopic characteristics of the system by means of simple electrochemical measurements.

Ab Initio Analysis of Auger-Assisted Electron Transfer.

PubMed

Hyeon-Deuk, Kim; Kim, Joonghan; Prezhdo, Oleg V

2015-01-15

Quantum confinement in nanoscale materials allows Auger-type electron-hole energy exchange. We show by direct time-domain atomistic simulation and analytic theory that Auger processes give rise to a new mechanism of charge transfer (CT) on the nanoscale. Auger-assisted CT eliminates the renown Marcus inverted regime, rationalizing recent experiments on CT from quantum dots to molecular adsorbates. The ab initio simulation reveals a complex interplay of the electron-hole and charge-phonon channels of energy exchange, demonstrating a variety of CT scenarios. The developed Marcus rate theory for Auger-assisted CT describes, without adjustable parameters, the experimental plateau of the CT rate in the region of large donor-acceptor energy gap. The analytic theory and atomistic insights apply broadly to charge and energy transfer in nanoscale systems.

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A Simple and High-Throughput Analysis of Amatoxins and Phallotoxins in Human Plasma, Serum and Urine Using UPLC-MS/MS Combined with PRiME HLB μElution Platform

PubMed Central

Zhang, Shuo; Zhao, Yunfeng; Li, Haijiao; Zhou, Shuang; Chen, Dawei; Zhang, Yizhe; Yao, Qunmei; Sun, Chengye

2016-01-01

Amatoxins and phallotoxins are toxic cyclopeptides found in the genus Amanita and are among the predominant causes of fatal food poisoning in China. In the treatment of Amanita mushroom poisoning, an early and definite diagnosis is necessary for a successful outcome, which has prompted the development of protocols for the fast and confirmatory determination of amatoxins and phallotoxins in human biological fluids. For this purpose, a simple, rapid and sensitive multiresidue UPLC-MS/MS method for the simultaneous determination of α-amanitin, β-amanitin, γ-amanitin, phalloidin (PHD) and phallacidin (PCD) in human plasma, serum and urine was developed and validated. The diluted plasma, serum and urine samples were directly purified with a novel PRiME technique on a 96-well μElution plate platform, which allowed high-throughput sample processing and low reagent consumption. After purification, a UPLC-MS/MS analysis was performed using positive electrospray ionization (ESI+) in multiple reaction monitoring (MRM) mode. This method fulfilled the requirements of a validation test, with good results for the limit of detection (LOD), lower limit of quantification (LLOQ), accuracy, intra- and inter-assay precision, recovery and matrix effects. All of the analytes were confirmed and quantified in authentic plasma, serum and urine samples obtained from cases of poisoning using this method. Using the PRiME μElution technique for quantification reduces labor and time costs and represents a suitable method for routine toxicological and clinical emergency analysis. PMID:27153089

The Tiberias Basin salt deposits and their effects on lake salinity

NASA Astrophysics Data System (ADS)

Inbar, Nimrod; Rosenthal, Eliahu; Möller, Peter; Yellin-Dror, Annat; Guttman, Josef; Siebert, Christian; Magri, Fabien

2015-04-01

Lake Tiberias is situated in one of the pull-apart basins comprising the Dead Sea transform. The Tiberias basin extends along the northern boundary of the Lower Jordan Rift Valley (LJRV) which is known for its massive salt deposits, mostly at its southern end, at the Dead Sea basin. Nevertheless, prior to the drilling of Zemah-1 wildcat, drilled close to the southern shores of Lake Tiberias, the Tiberias Basin was considered rather shallow and free of salt deposits (Starinsky, 1974). In 1983, Zemah-1 wildcat penetrated 2.8 km thick sequence of sedimentary and magmatic rocks of which 980m are salt deposits (Marcus et al., 1984). Recent studies, including the presented geophysical investigations, lay out the mechanisms of salt deposition in the Tiberias basin and estimate its abundance. Supported by seismic data, our interpreted cross-sections display relatively thick salt deposits distributed over the entire basin. Since early days of hydrological research in the area, saline springs are known to exist at Lake Tiberias' surroundings. Water temperatures in some of the springs indicate their origin to be at depths of 2-3 km (Simon and Mero, 1992). In the last decade, several studies suggested that the salinity of springs may be attributed, at least partially, to the Zemah-1 salt deposits. Chemical justification was attributed to post-halite minerals which were thought to be present among those deposits. This hypothesis was never verified. Moreover, Möller et al. (2011) presented a calculation contradicting this theory. In addition to the geophysical investigations, numerical models of thermally driven flow, examine the possible fluid dynamics developing near salt deposits below the lake and their interactions with springs along the lakeshore (Magri et al., 2015). It is shown that leached halite is too heavy to reach the surface. However, salt diffusing from shallow salt crest may locally reach the western side of the lakeshore. References Magri, F., N. Inbar,C. Siebert, E. Rosenthal, J. Guttman and P. Möller (2015) Transient simulations of large-scale hydrogeological processes causing temperature and salinity anomalies in the Tiberias Basin, Journal of Hydrology, Volume 520, Pages 342-355, Marcus, E., Y. Slager, S. Ben-Zaken, and I. Y. Indik (1984), Zemah 1, Geological Complition ReportRep. 84/11, 108 pp, Oil Exploration (Investments) LTD, Tel Aviv. Möller, P., C. Siebert, S. Geyer, N. Inbar, E. Rosenthal, A. Flexer, and M. Zilberbrand (2011), Relationships of Brines in the Kinnarot Basin, Jordan-Dead Sea Rift Valley, Geofluids (doi: 10.1111/j.1468-8123.2011.00353.x). Simon, E., and F. Mero (1992), The salinization mechanism of Lake Kinneret, J. Hydrol., 138, 327-343. Starinsky, A. (1974), Relationship between Ca-Chloride Brines and Sedimentary Rocks in Israel, PhD thesis, 84 pp, Hebrew University, Jerusalem.

A Critical Theory Perspective on Accelerated Learning.

ERIC Educational Resources Information Center

Brookfield, Stephen D.

2003-01-01

Critically analyzes accelerated learning using concepts from Herbert Marcuse (rebellious subjectivity) and Erich Fromm (automaton conformity). Concludes that, by providing distance and separation, accelerated learning has more potential to stimulate critical autonomous thought. (SK)

A nonmonotonic dependence of standard rate constant on reorganization energy for heterogeneous electron transfer processes on electrode surface

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu Weilin; Li Songtao; Zhou Xiaochun

2006-05-07

In the present work a nonmonotonic dependence of standard rate constant (k{sup 0}) on reorganization energy ({lambda}) was discovered qualitatively from electron transfer (Marcus-Hush-Levich) theory for heterogeneous electron transfer processes on electrode surface. It was found that the nonmonotonic dependence of k{sup 0} on {lambda} is another result, besides the disappearance of the famous Marcus inverted region, coming from the continuum of electronic states in electrode: with the increase of {lambda}, the states for both Process I and Process II ET processes all vary from nonadiabatic to adiabatic state continuously, and the {lambda} dependence of k{sup 0} for Process Imore » is monotonic thoroughly, while for Process II on electrode surface the {lambda} dependence of k{sup 0} could show a nonmonotonicity.« less

Reactive trajectories of the Ru2+/3+ self-exchange reaction and the connection to Marcus' theory.

PubMed

Tiwari, Ambuj; Ensing, Bernd

2016-12-22

Outer sphere electron transfer between two ions in aqueous solution is a rare event on the time scale of first principles molecular dynamics simulations. We have used transition path sampling to generate an ensemble of reactive trajectories of the self-exchange reaction between a pair of Ru 2+ and Ru 3+ ions in water. To distinguish between the reactant and product states, we use as an order parameter the position of the maximally localised Wannier center associated with the transferring electron. This allows us to align the trajectories with respect to the moment of barrier crossing and compute statistical averages over the path ensemble. We compare our order parameter with two typical reaction coordinates used in applications of Marcus theory of electron transfer: the vertical gap energy and the solvent electrostatic potential at the ions.

[The Antonine plague].

PubMed

Haas, Charles

2006-01-01

During the reign of Marcus Aurelius, the Roman Empire was struck by a long and destructive epidemic. It began in Mesopotamia in late AD 165 or early AD 166 during Verus' Parthian campaign, and quickly spread to Rome. It lasted at least until the death of Marcus Aurelius in AD 180 and likely into the early part of Commodus' reign. Its victims were "innumerable". Galen had first-hand knowledge of the disease. He was in Rome when the plague reached the city in AD 166. He was also present during an outbreak among troops stationed at Aquileia during the winter of AD 168-169. His references to the plague are scattered and brief but enough information is available to firmly identify the plague as smallpox. His description of the exanthema is fairly typical of the smallpox rash, particularly in the hemorrhagic phase of the disease.

[The use of opium in Roman society and the dependence of Princeps Marcus Aurelius].

PubMed

Trancas, Bruno; Borja Santos, Nuno; Patrício, Luís D

2008-01-01

Opium was known and frequently used in Roman society. Medical practice recognized its usefulness as an analgesic, soporific, anti-tussic or anti-diarrheic agent, as well as other currently unsupported uses with quasi-magical properties. It was additionally used as an ingredient in antidotes, panaceas and poisons. The authors present a non-exhaustive compilation of opium use according to medical doctors, writers and encyclopaedists of the time. Mythological and literary representations of the opium poppy reflected its diverse roles, being associated with prosperity and fertility, sleep, death and the underworld and with the art of medicine. Despite its free and routine use, there is no solid evidence of addiction, except the putative case of emperor Marcus Aurelius, consistently reported as one of the most likely cases of addiction to opium.

Photoinduced electron transfer in an imidazolium ionic liquid and in its binary mixtures with water, methanol, and 2-propanol: appearance of Marcus-type of inversion.

PubMed

Sarkar, Souravi; Mandal, Sarthak; Ghatak, Chiranjib; Rao, Vishal Govind; Ghosh, Surajit; Sarkar, Nilmoni

2012-02-02

The photoinduced electron transfer (PET) reaction has been investigated in a room temperature imidazolium ionic liquid (RTIL), 1-ethyl-3-methylimidazolium ethyl sulfate ([Emim][EtSO(4)]) and also in [Emim][EtSO(4)]-co-solvents mixtures from N,N-dimethyl aniline (DMA) to different Coumarin dyes using steady state and time-resolved fluorescence quenching measurements. We have used water and methanol and 2-propanol as the cosolvents of RTILs for the PET study. On going from neat ionic liquid to the RTIL-co-solvents mixtures the electron transfer rate has been largely enhanced. In neat RTIL as well as in [Emim][EtSO(4)]-co-solvents mixtures, a Marcus type of inversion in the PET rate have been observed.

DOE Office of Scientific and Technical Information (OSTI.GOV)

H. Nolen, S. Maxwell, R. Neri, J. Grab

This research effort sought to achieve a solution package that yields energy savings greater than 30 percent over the pre-existing conditions in a minimally intrusive multifamily retrofit project. The Consortium for Advanced Residential Buildings (CARB) partnered with L+M Development Partners, Inc. on a Mitchell-Lama Housing Program project, Marcus Garvey Village, in Brooklyn, NY (Climate Zone 4A). The Mitchell-Lama Housing Program is a form of housing subsidy in the state of New York that provides affordable rental and cooperative housing to moderate- and middle-income families. Marcus Garvey Village was founded in 1975 and contains 625 residential units (ranging from studios tomore » 5-bedroom units) in thirty-two 4-story garden-style apartment structures built with concrete and faced in light brown brick. The single largest challenge for implementation of energy conservation measures at Marcus Garvey was working within occupied spaces. Measures are being implemented in phases to minimize disruption. As of August 2015, the retrofit work is over 50 percent complete. The wall insulation, sealing of the through wall AC vent, and installation of new oil-filled electric baseboards with advanced controls are conducted at one time, limiting disruption to the living room space. In a similar fashion, the kitchen work is done, then the bathroom. The final selection of energy conservation measures is projected to save 26.5 percent in source energy with a cost just under $3.7 million and utility bill savings of nearly $480,000 (of an average $1.8 million annual utility cost for the development).« less

Large impact of reorganization energy on photovoltaic conversion due to interfacial charge-transfer transitions.

PubMed

Fujisawa, Jun-ichi

2015-05-14

Interfacial charge-transfer (ICT) transitions are expected to be a novel charge-separation mechanism for efficient photovoltaic conversion featuring one-step charge separation without energy loss. Photovoltaic conversion due to ICT transitions has been investigated using several TiO2-organic hybrid materials that show organic-to-inorganic ICT transitions in the visible region. In applications of ICT transitions to photovoltaic conversion, there is a significant problem that rapid carrier recombination is caused by organic-inorganic electronic coupling that is necessary for the ICT transitions. In order to solve this problem, in this work, I have theoretically studied light-to-current conversions due to the ICT transitions on the basis of the Marcus theory with density functional theory (DFT) and time-dependent DFT (TD-DFT) calculations. An apparent correlation between the reported incident photon-to-current conversion efficiencies (IPCE) and calculated reorganization energies was clearly found, in which the IPCE increases with decreasing the reorganization energy consistent with the Marcus theory in the inverted region. This activation-energy dependence was systematically explained by the equation formulated by the Marcus theory based on a simple excited-state kinetic scheme. This result indicates that the reduction of the reorganization energy can suppress the carrier recombination and enhance the IPCE. The reorganization energy is predominantly governed by the structural change in the chemical-adsorption moiety between the ground and ICT excited states. This work provides crucial knowledge for efficient photovoltaic conversion due to ICT transitions.

A Novel Phenanthrene Dioxygenase from Nocardioides sp. Strain KP7: Expression in Escherichia coli

PubMed Central

Saito, Atsushi; Iwabuchi, Tokuro; Harayama, Shigeaki

2000-01-01

Nocardioides sp. strain KP7 grows on phenanthrene but not on naphthalene. This organism degrades phenanthrene via 1-hydroxy-2-naphthoate, o-phthalate, and protocatechuate. The genes responsible for the degradation of phenanthrene to o-phthalate (phd) were found by Southern hybridization to reside on the chromosome. A 10.6-kb DNA fragment containing eight phd genes was cloned and sequenced. The phdA, phdB, phdC, and phdD genes, which encode the α and β subunits of the oxygenase component, a ferredoxin, and a ferredoxin reductase, respectively, of phenanthrene dioxygenase were identified. The gene cluster, phdAB, was located 8.3 kb downstream of the previously characterized phdK gene, which encodes 2-carboxybenzaldehyde dehydrogenase. The phdCD gene cluster was located 2.9 kb downstream of the phdB gene. PhdA and PhdB exhibited moderate (less than 60%) sequence identity to the α and β subunits of other ring-hydroxylating dioxygenases. The PhdC sequence showed features of a [3Fe-4S] or [4Fe-4S] type of ferredoxin, not of the [2Fe-2S] type of ferredoxin that has been found in most of the reported ring-hydroxylating dioxygenases. PhdD also showed moderate (less than 40%) sequence identity to known reductases. The phdABCD genes were expressed poorly in Escherichia coli, even when placed under the control of strong promoters. The introduction of a Shine-Dalgarno sequence upstream of each initiation codon of the phdABCD genes improved their expression in E. coli. E. coli cells carrying phdBCD or phdACD exhibited no phenanthrene-degrading activity, and those carrying phdABD or phdABC exhibited phenanthrene-degrading activity which was significantly less than that in cells carrying the phdABCD genes. It was thus concluded that all of the phdABCD genes are necessary for the efficient expression of phenanthrene-degrading activity. The genetic organization of the phd genes, the phylogenetically diverged positions of these genes, and an unusual type of ferredoxin component suggest phenanthrene dioxygenase in Nocardioides sp. strain KP7 to be a new class of aromatic ring-hydroxylating dioxygenases. PMID:10735855

The First Journalism School.

ERIC Educational Resources Information Center

Boyle, Diane

2000-01-01

Offers a brief look at the life of Marcus Walter Williams: his early life and education, his work life in journalism, and his founding of the first school of Journalism (located at the University of Missouri) in 1906. (SR)

A Faculty Trains Itself to Improve Student Discipline

ERIC Educational Resources Information Center

Grantham, Marvin L.; Harris, Clifton S., Jr.

1976-01-01

The Marcus School staff feels that the best approach to discipline is a preventive one--the provision of a variety of educational and environmental alternatives that will interest, challenge, and motivate the pupil. (Author)

AGU 2002-2003 Congressional Science Fellow

NASA Astrophysics Data System (ADS)

Illa Amerson, a Ph.D. candidate at the Oregon Health & Science University in Beaverton, was selected as AGU's 26th Congressional Science Fellow for 2002-2003. Starting in September, Amerson will serve a one-year assignment in the office of a senator or representative, or on a committee's staff as one of only a handful of scientists on Capitol Hill in Washington, D.C. Once in an office, Amerson can expect to work as a regular member of the staff, serving as a legislative assistant. Her duties could include advising her boss how to vote on specific bills, writing speeches or press releases, crafting legislation, meeting with lobbyists and special interest groups, and even answering constituent mail.Amerson expects to receive her Ph.D. in environmental science and engineering this summer. Her dissertation focuses on the environmental impact of the gasoline additive methyl tert-butyl ether (MTBE). She completed a M.S. in civil and environmental engineering at Arizona State University and a S.B. in chemical engineering at the Massachusetts Institute of Technology Amerson has also spent three years working in environmental regulation and consulting, dealing primarily with air and water quality issues.

Approaches to Design and Evaluation of Sandwich Composites

NASA Technical Reports Server (NTRS)

Shivakumar, Kunigal; Raju, I. S. (Technical Monitor); Ambur, D. (Technical Monitor)

2001-01-01

This report describes research during the period June 15, 1997 to October 31, 2000. This grant yielded a low cast manufacturing of composite sandwich structures technology and characterization interfacial and subinterfacial cracks in foam core sandwich panels. The manufacturing technology is called the vacuum assisted resin transfer (VARTM). The VARTM is suitable for processing composite materials both at ambient and elevated temperatures and of unlimited component size. This technology has been successfully transferred to a small business fiber preform manufacturing company 3TEX located in Cary, North Carolina. The grant also supported one Ph.D, one M.S and a number of under graduate students, and nine publications and Presentations.

Response of the Cardiovascular System to Vibration and Combined Stresses

DTIC Science & Technology

1983-11-30

D . John B. Charles. Ph.D.Pr Benjamin S. KelleyPh.D. CD JUN1 9 1984J LAA rpubi Ia release U1 trl OD1 uflhimitod. U’= -’ Wenner-Gren Research...and Combined Stresses 4. PeRIVORUING OitG. RECPORT HuMUS FI 7. AUTHORrs) 6. C01YR ACT 04 GRANT NUMBER(#) C. F. Knapp, Ph. D ., J. M. Evans, M.S. D . C...Randall, Ph. D ., J. B. Charles, Ph. D . and F92-3K00 B. S. Kelley, PhD. 9.PERFORMN 10NZTO AI N DRS to. PROGRAM ELEMENT. PROJECT, TASK IWO~~RE ARAITO

Filling the Graduate Student Pipeline

NASA Astrophysics Data System (ADS)

Winey, Karen I.

2003-03-01

As a professor who relies on graduate students to participate in my research program, I work to ensure that the pipeline of graduate students is full. This presentation will discuss a variety of strategies that I have used to advertise the opportunities of graduate school, many of which use existing infrastructure at the University of Pennsylvania. These strategies involve a combination of public speaking, discussion groups, and faculty advising. During these exchanges it's important to both contrast the career opportunities for B.S., M.S. and Ph.D. degree holders and outline the financial facts about graduate school. These modest efforts have increased the number of Penn undergraduates pursuing doctorate degrees.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Laskin, Julia

In this work, resonant ejection coupled with surface-induced dissociation (SID) in a Fourier transform ion cyclotron resonance mass spectrometer is used to examine fragmentation kinetics of two singly protonated hexapeptides, RYGGFL and KYGGFL, containing the basic arginine residue and less basic lysine residue at the N-terminus. The kinetics of individual reaction channels at different collision energies are probed by applying a short ejection pulse (1 ms) in resonance with the cyclotron frequency of a selected fragment ion and varying the delay time between ion-surface collision and resonant ejection while keeping total reaction delay time constant. Rice-Ramsperger-Kassel-Marcus (RRKM) modeling of themore » experimental data provides accurate threshold energies and activation entropies of individual reaction channels. Substitution of arginine with less basic lysine has a pronounced effect on the observed fragmentation kinetics of several pathways, including the b2 ion formation, but has little or no effect on formation of the b5+H2O fragment ion. The combination of resonant ejection SID, time- and collision energy-resolved SID, and RRKM modeling of both types of experimental data provides a detailed mechanistic understanding of the primary dissociation pathways of complex gaseous ions.« less

NCCU/BBRI-Duke/Urology Partnership in Prostate Cancer Research

DTIC Science & Technology

2008-06-01

Somnath Muhopadhyay, Ph.D.; Joellen Schildkraut, Ph.D.; David Tulis , Ph.D.; Leon Sun, Ph.D.; Lee Jones, Ph.D.; Phillip 5e. TASK NUMBER Febbo, Ph.D...Community-Based Intervention Investigators: Dave Tulis Ph.D., NCCU/BBRI Collaborators: Catherine Hoyo, PhD; Lee Jones, PhD; Stephen Freeland...addition, Dr. David Tulis (NCCU PI) who was working on the exercise project with Dr. Lee Jones (Duke PI), has recently accepted a position at East Carolina

Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin

PubMed Central

Liu, Qingdu; Binns, Thomas C.; Davidoff, Olena; Kapitsinou, Pinelopi P.; Pfaff, Andrew S.; Olauson, Hannes; Fogo, Agnes B.; Fong, Guo-Hua; Gross, Kenneth W.

2016-01-01

Renal peritubular interstitial fibroblast-like cells are critical for adult erythropoiesis, as they are the main source of erythropoietin (EPO). Hypoxia-inducible factor 2 (HIF-2) controls EPO synthesis in the kidney and liver and is regulated by prolyl-4-hydroxylase domain (PHD) dioxygenases PHD1, PHD2, and PHD3, which function as cellular oxygen sensors. Renal interstitial cells with EPO-producing capacity are poorly characterized, and the role of the PHD/HIF-2 axis in renal EPO-producing cell (REPC) plasticity is unclear. Here we targeted the PHD/HIF-2/EPO axis in FOXD1 stroma-derived renal interstitial cells and examined the role of individual PHDs in REPC pool size regulation and renal EPO output. Renal interstitial cells with EPO-producing capacity were entirely derived from FOXD1-expressing stroma, and Phd2 inactivation alone induced renal Epo in a limited number of renal interstitial cells. EPO induction was submaximal, as hypoxia or pharmacologic PHD inhibition further increased the REPC fraction among Phd2–/– renal interstitial cells. Moreover, Phd1 and Phd3 were differentially expressed in renal interstitium, and heterozygous deficiency for Phd1 and Phd3 increased REPC numbers in Phd2–/– mice. We propose that FOXD1 lineage renal interstitial cells consist of distinct subpopulations that differ in their responsiveness to Phd2 inactivation and thus regulation of HIF-2 activity and EPO production under hypoxia or conditions of pharmacologic or genetic PHD inactivation. PMID:27088801

A Simple Geometric Model for the Marcus Theory of Proton Transfer

ERIC Educational Resources Information Center

McLennan, Duncan J.

1976-01-01

Uses the intersecting parabola model to derive an equation that relates the observed free energy of activation for a slow proton transfer to the overall thermodynamic free energy change in the reaction. (MLH)

78 FR 24798 - Qualification of Drivers; Exemption Applications; Vision

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-26

... exceeded the speed limit by 13 mph. Marcus R. Watkins Mr. Watkins, 50, has had a retinal detachment in his... vision to perform driving tasks required to operate a commercial vehicle.'' Mr. Watkins reported that he...

On the non-Arrhenius temperature dependence of the interwell electron tunneling rate in quasi two dimensional organic quantum wells

NASA Astrophysics Data System (ADS)

Jeong, I. S.; Scott, K.; Donovan, K. J.; Wilson, E. G.

2000-11-01

The tunneling rate of photocreated charge carriers between layers in Langmuir-Blodgett multilayer structures is measured indirectly using the novel technique of bimolecular recombination quenching. The tunneling rate is measured as a function of the applied electrostatic potential difference between the layers as the temperature is varied between 300 and 4 K. This dependence is examined in light of the Marcus theory of charge transfer where the electrostatic potential replaces the chemical potential as the driving potential. The expectations of the Marcus theory are not met and the rate is effectively temperature independent, contrary to expectation. Other mechanisms are explored that may explain the lack of temperature dependence including the role of high frequency vibrations and the role of the zero point energy of those vibrations. The temperature dependence of the exciton dissociation probability is also examined.

Adiabatic elimination for systems with inertia driven by compound Poisson colored noise.

PubMed

Li, Tiejun; Min, Bin; Wang, Zhiming

2014-02-01

We consider the dynamics of systems driven by compound Poisson colored noise in the presence of inertia. We study the limit when the frictional relaxation time and the noise autocorrelation time both tend to zero. We show that the Itô and Marcus stochastic calculuses naturally arise depending on these two time scales, and an extra intermediate type occurs when the two time scales are comparable. This leads to three different limiting regimes which are supported by numerical simulations. Furthermore, we establish that when the resulting compound Poisson process tends to the Wiener process in the frequent jump limit the Itô and Marcus calculuses, respectively, tend to the classical Itô and Stratonovich calculuses for Gaussian white noise, and the crossover type calculus tends to a crossover between the Itô and Stratonovich calculuses. Our results would be very helpful for understanding relevant experiments when jump type noise is involved.

Effects of tunnelling and asymmetry for system-bath models of electron transfer

NASA Astrophysics Data System (ADS)

Mattiat, Johann; Richardson, Jeremy O.

2018-03-01

We apply the newly derived nonadiabatic golden-rule instanton theory to asymmetric models describing electron-transfer in solution. The models go beyond the usual spin-boson description and have anharmonic free-energy surfaces with different values for the reactant and product reorganization energies. The instanton method gives an excellent description of the behaviour of the rate constant with respect to asymmetry for the whole range studied. We derive a general formula for an asymmetric version of the Marcus theory based on the classical limit of the instanton and find that this gives significant corrections to the standard Marcus theory. A scheme is given to compute this rate based only on equilibrium simulations. We also compare the rate constants obtained by the instanton method with its classical limit to study the effect of tunnelling and other quantum nuclear effects. These quantum effects can increase the rate constant by orders of magnitude.

Model of a thin film optical fiber fluorosensor

NASA Technical Reports Server (NTRS)

Egalon, Claudio O.; Rogowski, Robert S.

1991-01-01

The efficiency of core-light injection from sources in the cladding of an optical fiber is modeled analytically by means of the exact field solution of a step-profile fiber. The analysis is based on the techniques by Marcuse (1988) in which the sources are treated as infinitesimal electric currents with random phase and orientation that excite radiation fields and bound modes. Expressions are developed based on an infinite cladding approximation which yield the power efficiency for a fiber coated with fluorescent sources in the core/cladding interface. Marcuse's results are confirmed for the case of a weakly guiding cylindrical fiber with fluorescent sources uniformly distributed in the cladding, and the power efficiency is shown to be practically constant for variable wavelengths and core radii. The most efficient fibers have the thin film located at the core/cladding boundary, and fibers with larger differences in the indices of refraction are shown to be the most efficient.

A Knock-in Mouse Model of Human PHD2 Gene-associated Erythrocytosis Establishes a Haploinsufficiency Mechanism*

PubMed Central

Arsenault, Patrick R.; Pei, Fei; Lee, Rebecca; Kerestes, Heddy; Percy, Melanie J.; Keith, Brian; Simon, M. Celeste; Lappin, Terence R. J.; Khurana, Tejvir S.; Lee, Frank S.

2013-01-01

The central pathway for controlling red cell mass is the PHD (prolyl hydroxylase domain protein):hypoxia-inducible factor (HIF) pathway. HIF, which is negatively regulated by PHD, activates numerous genes, including ones involved in erythropoiesis, such as the ERYTHROPOIETIN (EPO) gene. Recent studies have implicated PHD2 as the key PHD isoform regulating red cell mass. Studies of humans have identified erythrocytosis-associated, heterozygous point mutations in the PHD2 gene. A key question concerns the mechanism by which human mutations lead to phenotypes. In the present report, we generated and characterized a mouse line in which a P294R knock-in mutation has been introduced into the mouse Phd2 locus to model the first reported human PHD2 mutation (P317R). Phd2P294R/+ mice display a degree of erythrocytosis equivalent to that seen in Phd2+/− mice. The Phd2P294R/+-associated erythrocytosis is reversed in a Hif2a+/−, but not a Hif1a+/− background. Additional studies using various conditional knock-outs of Phd2 reveal that erythrocytosis can be induced by homozygous and heterozygous knock-out of Phd2 in renal cortical interstitial cells using a Pax3-Cre transgene or by homozygous knock-out of Phd2 in hematopoietic progenitors driven by a Vav1-Cre transgene. These studies formally prove that a missense mutation in PHD2 is the cause of the erythrocytosis, show that this occurs through haploinsufficiency, and point to multifactorial control of red cell mass by PHD2. PMID:24121508

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chęcińska, Agata; Heaney, Libby; Pollock, Felix A.

Motivated by a proposed olfactory mechanism based on a vibrationally activated molecular switch, we study electron transport within a donor-acceptor pair that is coupled to a vibrational mode and embedded in a surrounding environment. We derive a polaron master equation with which we study the dynamics of both the electronic and vibrational degrees of freedom beyond previously employed semiclassical (Marcus-Jortner) rate analyses. We show (i) that in the absence of explicit dissipation of the vibrational mode, the semiclassical approach is generally unable to capture the dynamics predicted by our master equation due to both its assumption of one-way (exponential) electronmore » transfer from donor to acceptor and its neglect of the spectral details of the environment; (ii) that by additionally allowing strong dissipation to act on the odorant vibrational mode, we can recover exponential electron transfer, though typically at a rate that differs from that given by the Marcus-Jortner expression; (iii) that the ability of the molecular switch to discriminate between the presence and absence of the odorant, and its sensitivity to the odorant vibrational frequency, is enhanced significantly in this strong dissipation regime, when compared to the case without mode dissipation; and (iv) that details of the environment absent from previous Marcus-Jortner analyses can also dramatically alter the sensitivity of the molecular switch, in particular, allowing its frequency resolution to be improved. Our results thus demonstrate the constructive role dissipation can play in facilitating sensitive and selective operation in molecular switch devices, as well as the inadequacy of semiclassical rate equations in analysing such behaviour over a wide range of parameters.« less

Retrofitting Garden-Style Apartments in Brooklyn, New York

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nolen, Heather; Maxwell, Sean; Neri, Robin

This research effort sought to achieve a solution package that yields energy savings greater than 30% over the pre-existing conditions in a minimally intrusive multifamily retrofit project. The Consortium for Advanced Residential Buildings (CARB) partnered with L+M Development Partners, Inc. on a Mitchell-Lama Housing Program project, Marcus Garvey Village, in Brooklyn, NY (Climate Zone 4A). The Mitchell-Lama Housing Program is a form of housing subsidy in the state of New York that provides affordable rental and cooperative housing to moderate- and middle-income families. Marcus Garvey Village was founded in 1975 and contains 625 residential units (ranging from studios to 5-bedroommore » units) in thirty-two 4-story garden-style apartment structures built with concrete and faced in light brown brick. The single largest challenge for implementation of energy conservation measures at Marcus Garvey was working within occupied spaces. Measures are being implemented in phases to minimize disruption. As of August 2015, the retrofit work is over 50% complete. The wall insulation, sealing of the through wall AC vent, and installation of new oil-filled electric baseboards with advanced controls are conducted at one time, limiting disruption to the living room space. In a similar fashion, the kitchen work is done, then the bathroom. The final selection of energy conservation measures is projected to save 26.5% in source energy with a cost just under $3.7 million and utility bill savings of nearly $480,000 (of an average $1.8 million annual utility cost for the development).« less

Building America Case Study: Retrofitting Garden-Style Apartments, Brooklyn, New York

DOE Office of Scientific and Technical Information (OSTI.GOV)

This research effort sought to achieve a solution package that yields energy savings greater than 30 percent over the pre-existing conditions in a minimally intrusive multifamily retrofit project. The Consortium for Advanced Residential Buildings (CARB) partnered with L+M Development Partners, Inc. on a Mitchell-Lama Housing Program project, Marcus Garvey Village, in Brooklyn, NY (Climate Zone 4A). The Mitchell-Lama Housing Program is a form of housing subsidy in the state of New York that provides affordable rental and cooperative housing to moderate- and middle-income families. Marcus Garvey Village was founded in 1975 and contains 625 residential units (ranging from studios tomore » 5-bedroom units) in thirty-two 4-story garden-style apartment structures built with concrete and faced in light brown brick. The single largest challenge for implementation of energy conservation measures at Marcus Garvey was working within occupied spaces. Measures are being implemented in phases to minimize disruption. As of August 2015, the retrofit work is over 50 percent complete. The wall insulation, sealing of the through wall AC vent, and installation of new oil-filled electric baseboards with advanced controls are conducted at one time, limiting disruption to the living room space. In a similar fashion, the kitchen work is done, then the bathroom. The final selection of energy conservation measures is projected to save 26.5 percent in source energy with a cost just under $3.7 million and utility bill savings of nearly $480,000 (of an average $1.8 million annual utility cost for the development).« less

Gold Medal Award for Life Achievement in the Science of Psychology: Lynn Nadel.

PubMed

2017-01-01

The American Psychological Foundation (APF) Gold Medal Awards recognize distinguished and engaging records of accomplishment in 4 areas of psychology. The 2017 recipient of the Gold Medal Award for Life Achievement in the Science of Psychology is Lynn Nadel, PhD. Terence M. Keane, PhD, president of the APF, will present the APF Gold Medal Awards at the 125th Annual Convention of the American Psychological Association on August 4, 2017, at 4:00 p.m. Members of the 2017 APF Board of Trustees are Terence M. Keane, PhD, president; Melba J. T. Vasquez, PhD, vice president-interim secretary; Richard C. McCarty, PhD, treasurer; Elisabeth R. Straus, executive vice president-executive director; Camilla Benbow, EdD; Rosie Phillips Bingham, PhD; Connie S. Chan; Arthur C. Evans, Jr., PhD; Linda M. Forrest, PhD; Douglas C. Haldeman, PhD; Anthony W. Jackson, PhD; Archie L. Turner; W. Bruce Walsh, PhD; and Stewart E. Cooper, PhD, APA Board of Directors liaison. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Retention of prolyl hydroxylase PHD2 in the cytoplasm prevents PHD2-induced anchorage-independent carcinoma cell growth

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jokilehto, Terhi; Turku Graduate School of Biomedical Sciences, Turku; Hoegel, Heidi

2010-04-15

Cellular oxygen tension is sensed by a family of prolyl hydroxylases (PHD1-3) that regulate the degradation of hypoxia-inducible factors (HIF-1{alpha} and -2{alpha}). The PHD2 isoform is considered as the main downregulator of HIF in normoxia. Our previous results have shown that nuclear translocation of PHD2 associates with poorly differentiated tumor phenotype implying that nuclear PHD2 expression is advantageous for tumor growth. Here we show that a pool of PHD2 is shuttled between the nucleus and the cytoplasm. In line with this, accumulation of wild type PHD2 in the nucleus was detected in human colon adenocarcinomas and in cultured carcinoma cells.more » The PHD2 isoforms showing high nuclear expression increased anchorage-independent carcinoma cell growth. However, retention of PHD2 in the cytoplasm inhibited the anchorage-independent cell growth. A region that inhibits the nuclear localization of PHD2 was identified and the deletion of the region promoted anchorage-independent growth of carcinoma cells. Finally, the cytoplasmic PHD2, as compared with the nuclear PHD2, less efficiently downregulated HIF expression. Forced HIF-1{alpha} or -2{alpha} expression decreased and attenuation of HIF expression increased the anchorage-independent cell growth. However, hydroxylase-inactivating mutations in PHD2 had no effect on cell growth. The data imply that nuclear PHD2 localization promotes malignant cancer phenotype.« less

B.S. Chemists: Experience and prospects in a changing scientific and technical environment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Russell, T.; Burrelli, J.S.

1995-12-31

The men and women who hold a Bachelor`s degree in chemistry as their highest academic degree are an important for chemistry as their highest academic degree are an important for chemistry and science generally. {open_quotes}BS chemists{close_quotes} are the pool of U.S. residents from which future chemistry Ph.D.s (80 percent of them) and MDs (9 percent of the 1990 medical school class) are recruited and the basic pool of scientific and technical manpower for chemical and related industries. BS chemists are the most heterogeneous of all chemist groups and the most mobile: even at graduation, two-thirds of them intend to bemore » something else -- a Ph.D., MD, MBA, etc. -- in the near future. The mobility of many BS chemists is more to other careers, and hence the diffusion of chemical knowledge throughout the occupational spectrum, is primarily an outflow of BS holders utilizing their scientific training in other fields. This talk describes the past and present circumstances of BS chemists and makes some forecasts about these people about these people and those who will be the graduate of four-year chemistry programs in the future. A number of private and federal agencies collect data on chemists, but to chart the situation of the BS graduate, this paper draws on data sets maintained by the National Science Foundation and the National Research Council, both on BS and, for comparison, Ph.D. holders. For clarity, this analysis will not deal with the situation of MS chemists who, on most indicators fall as intuition would tell us, between the BS and Ph.D. groups. We also draw heavily on ACS Comprehensive Member Surveys and the Starting Salary Surveys of new graduates so identified by their academic departments.« less

The Road to Remarkable: Directed by Vision, Driven by Strength--2010 Five-Year Report of the Policy and Planning Board

ERIC Educational Resources Information Center

American Psychologist, 2011

2011-01-01

The 2010 Policy and Planning Board of the American Psychological Association (APA) was chaired by Elena J. Eisman, EdD. Other members of the board included Gwyneth M. Boodoo, PhD; G. Rita Dudley-Grant, PhD; Beverly Greene, PhD; Christopher W. Loftis, PhD; Michael J. Murphy, PhD; Paul D. Nelson, PhD; Kurt Salzinger, PhD; and Michael Wertheimer,…

The panacea toolbox of a PhD biomedical student.

PubMed

Skaik, Younis

2014-01-01

Doing a PhD (doctor of philosophy) for the sake of contribution to knowledge should give the student an immense enthusiasm through the PhD period. It is the time in one's life that one spends to "hit the nail on the head" in a specific area and topic of interest. A PhD consists mostly of hard work and tenacity; however, luck and genius might also play a little role. You can pass all PhD phases without having both luck and genius. The PhD student should have pre-PhD and PhD toolboxes, which are "sine quibus non" for getting successfully a PhD degree. In this manuscript, the toolboxes of the PhD student are discussed.

Charles L. Brewer Award for Distinguished Teaching of Psychology: Regan A. R. Gurung.

PubMed

2017-01-01

The American Psychological Foundation (APF) Charles L. Brewer Award for Distinguished Teaching of Psychology recognizes exemplary career contributions to the teaching of psychology. The 2017 recipient of the Charles L. Brewer Award for Distinguished Teaching of Psychology is Regan A. R. Gurung, PhD. Terence M. Keane, PhD, president of the APF, will present the APF Charles L. Brewer Award for Distinguished Teaching of Psychology at the 125th Annual Convention of the American Psychological Association on August 4, 2017, at 4:00 p.m. Members of the 2017 APF Board of Trustees are Terence M. Keane, PhD, president; Melba J. T. Vasquez, PhD, vice president/interim secretary; Richard C. McCarty, PhD, treasurer; Elisabeth R. Straus, executive vice president/executive director; Camilla Benbow, EdD; Rosie Phillips Bingham, PhD; Connie S. Chan; Arthur C. Evans, Jr., PhD; Linda M. Forrest, PhD; Douglas C. Haldeman, PhD; Anthony W. Jackson, PhD; Archie L. Turner; W. Bruce Walsh, PhD; and Stewart E. Cooper, PhD, APA Board of Directors liaison. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Racism and Surplus Repression.

ERIC Educational Resources Information Center

Johnson, Howard

1983-01-01

Explores the relationship between Herbert Marcuse's theory of "surplus repression" and Freud's theory of the "unconscious" with respect to latent, hidden, covert, or subliminal aspects of racism in the United States. Argues that unconscious racism, manifested in evasion/avoidance, acting out/projection, and attempted…

Remediation System Evaluation, SMS Instruments Superfund Site

EPA Pesticide Factsheets

The SMS Instruments Superfund Site is located at 120 Marcus Boulevard in Deer Park, Suffolk County,New York. The site consists of a 34,000 square foot building located on a 1.5-acre lot that is surroundedby other light industrial facilities.

Australian DefenceScience. Volume 13, Number 2, Winter

DTIC Science & Technology

2005-01-01

has been marketing the OAVD technology through its Business and Commercialisation Office (BCO). Marcus Belder, Technology Commercialisation Manager...for ADF organisational structures, and training and education initiatives.” The inquiry process As one line of inquiry, the team has been carrying

Tuskegee Institute in the 1920's

ERIC Educational Resources Information Center

Marable, Manning

1977-01-01

During the time of Marcus Garvey, the Harlem Renaissance and Southern black labor militancy, Tuskegee perpetuated a conservative social philosophy. This contradictory legacy set the stage for a confrontation between the black middle class of Tuskegee and a white racist society. (Author/GC)

Surface-induced dissociation: a unique tool for studying energetics and kinetics of the gas-phase fragmentation of large ions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Laskin, Julia

2015-01-01

Surface-induced dissociation (SID) is valuable tool for investigating activation and dissociation of large ions in tandem mass spectrometry. This account summarizes key findings from studies of the energetics and mechanisms of complex ion dissociation, in which SID experiments were combined with Rice-Ramsperger-Kassel-Marcus (RRKM) modeling of the experimental data. These studies used time- and collision-energy-resolved SID experiments and SID combined with resonant ejection of selected fragment ions on a specially designed Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS). Fast ion activation by collision with a surface combined with the long and variable timescale of a FT-ICR MS is perfectlymore » suited for studying the energetics and dynamics of complex ion dissociation in the gas phase. Modeling of time- and collision-energy-resolved SID enables accurate determination of energy and entropy effects in the dissociation process. It has been demonstrated that entropy effects play an important role in determining the dissociation rates of both covalent and non-covalent bonds in large gaseous ions. SID studies have provided important insights on the competition between charge-directed and charge-remote fragmentation in even-electron peptide ions and the role of charge and radical site on the energetics of the dissociation of odd-electron peptide ions. Furthermore, this work examined factors that affect the strength of non-covalent binding, as well as the competition between covalent and non-covalent bond cleavages and between proton and electron transfer in model systems. Finally, SID studies have been used to understand the factors affecting nucleation and growth of clusters in solution and the gas phase.« less

Applied PhD Research in a Work-Based Environment: An Activity Theory-Based Analysis

ERIC Educational Resources Information Center

Granata, S. N.; Dochy, F.

2016-01-01

Activity theory is used to compare PhD undertaken at university, that is, academic PhD, with PhD performed in collaboration with industry, that is, semi-industrial PhD. The research is divided into a literature review and a case study. Semi-industrial and academic PhD are modelled as activity systems, and differences are highlighted in terms of…

STS-112 M.S. Magnus in white room before launch

NASA Technical Reports Server (NTRS)

2002-01-01

KENNEDY SPACE CENTER, FLA. - -- In the White Room at Launch Pad 39B, STS-112 Mission Specialist Sandra H. Magnus, Ph.D., receives assistance with her spacesuit before boarding Space Shuttle Atlantis. Liftoff is schedued for 3:46 p.m. EDT. Along with a crew of six, Atlantis will carry the S1 Integrated Truss Structure and the Crew and Equipment Translation Aid (CETA) Cart A to the International Space Station (ISS). The CETA is the first of two human-powered carts that will ride along the ISS railway, providing mobile work platforms for future spacewalking astronauts. On the 11-day mission, three spacewalks are planned to attach the S1 truss.

STS-112 M.S. Sellers in white room before launch

NASA Technical Reports Server (NTRS)

2002-01-01

KENNEDY SPACE CENTER, FLA. - -- In the White Room at Launch Pad 39B, STS-112 Mission Specialist Piers J. Sellers, Ph.D., receives assistance with his spacesuit before boarding Space Shuttle Atlantis. Liftoff is schedued for 3:46 p.m. EDT. Along with a crew of six, Atlantis will carry the S1 Integrated Truss Structure and the Crew and Equipment Translation Aid (CETA) Cart A to the International Space Station (ISS). The CETA is the first of two human-powered carts that will ride along the ISS railway, providing mobile work platforms for future spacewalking astronauts. On the 11-day mission, three spacewalks are planned to attach the S1 truss.

NASA Multidisciplinary Design and Analysis Fellowship Program

NASA Technical Reports Server (NTRS)

1995-01-01

This report is a Year 1 interim report of the progress on the NASA multidisciplinary Design and Analysis Fellowship Program covering the period, January 1, 1995 through September 30, 1995. It summarizes progress in establishing the MDA Fellowship Program at Georgia Tech during the initial year. Progress in the advertisement of the program, recruiting results for the 1995-96 academic year, placement of the Fellows in industry during Summer 1995, program development at the M.S. and Ph.D. levels, and collaboration and dissemination of results are summarized in this report. Further details of the first year's progress will be included in the report from the Year 1 Workshop to be held at NASA Langley on December 7-8, 1995.

Final Report: Enabling Exascale Hardware and Software Design through Scalable System Virtualization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bridges, Patrick G.

2015-02-01

In this grant, we enhanced the Palacios virtual machine monitor to increase its scalability and suitability for addressing exascale system software design issues. This included a wide range of research on core Palacios features, large-scale system emulation, fault injection, perfomrance monitoring, and VMM extensibility. This research resulted in large number of high-impact publications in well-known venues, the support of a number of students, and the graduation of two Ph.D. students and one M.S. student. In addition, our enhanced version of the Palacios virtual machine monitor has been adopted as a core element of the Hobbes operating system under active DOE-fundedmore » research and development.« less

GP Section selects Best Student Paper

NASA Astrophysics Data System (ADS)

The AGU Geomagnetism and Paleomagnetism (GP) Section has announced its selection of a paper entitled “Multicomponent Magnetization of the Upper Silurian-Lower Devonian Ringerike Sandstone, Adjacent Dikes, and Permian Lavas, Oslo, Norway” as the best GP student paper presented at the 1986 AGU Spring Meeting. The primary author, Dartmouth College Ph.D. candidate David Douglass, was assisted on the paper by a colleague from Lamont-Doherty Geological Observatory. Douglass received his B.S. in geology from the University of California, Los Angeles, in 1980, and in 1984, he received his M.S. in earth sciences at Dartmouth. His current studies examine the paleomagnetism, structure, and sedimentation of several North Atlantic old red sandstone basins.

STS-89 M.S. Andrew Thomas, poses the day before launch

NASA Technical Reports Server (NTRS)

1998-01-01

STS-89 Mission Specialist Andrew Thomas, Ph.D., poses at KSC's Launch Pad 39A wearing a miniature koala bear on the day before the scheduled launch of Space Shuttle Endeavour that will carry him up to the Russian Space Station Mir. Final preparations are under way toward liftoff on Jan. 22 on the eighth mission to dock with Mir. After docking, Dr. Thomas will transfer to the space station, succeeding David Wolf, M.D., who will return to Earth aboard Endeavour. Dr. Thomas, who was born and educated in South Australia, will live and work on Mir until June. STS-89 is scheduled for liftoff at 9:48 p.m. EST.

PhD Students' Work Conditions and Study Environment in University- and Industry-Based PhD Programmes

ERIC Educational Resources Information Center

Kolmos, A.; Kofoed, L. B.; Du, X. Y.

2008-01-01

During the last 10 years, new models of funding and training PhD students have been established in Denmark in order to integrate industry into the entire PhD education. Several programmes have been conducted where it is possible to co-finance PhD scholarships or to become an employee as an industrial PhD in a company. An important question is what…

Multimodality Image-Guided HDR/IMRT in Prostate Cancer: Combined Molecular Targeting Using Nanoparticle MR, 3D MRSI, and 11C Acetate PET Imaging

DTIC Science & Technology

2005-08-01

Ph.D. Panos Fatouros, Ph.D. Jerry Hirsch, MSc, PharmD Rhonda Hoyle Kristin Schmidt Dorin Tudor, Ph.D. Jie Liu CONTRACTING ORGANIZATION: Virginia...McClish, Ph.D., Panos Fatouros, Ph.D., Jerry Hirsch, MSc, PharmD, 5e. TASK NUMBER Rhonda Hoyle, Kristin Schmidt, Dorin Tudor, Ph.D., Jie Liu 5f. WORK UNIT

STS-127 Crew Visit to Anne Beers Elementary

NASA Image and Video Library

2009-09-23

Students, including Marcus Pratt, left, and Ajani Young, second from left, pay close attention as the crew from STS-127 makes their presentation during a visit to Anne Beers Elementary school, Thursday, Sept. 24, 2009, in Washington. Photo Credit: (NASA/Paul E. Alers)

Education on Trial. Strategies for the Future.

ERIC Educational Resources Information Center

Johnston, William J., Ed.

Problems and opportunities in educational reform at all educational levels are considered in this collection of 18 articles. Titles and authors are as follows: Introduction (William J. Johnston); "Evidence of Decline in Educational Standards" (Philip N. Marcus); "Standards--by What Criteria?" (Francis Keppel); "Educational…

Formation and characterization of a reactive chromium(v)–oxo complex: mechanistic insight into hydrogen-atom transfer reactions† †Electronic supplementary information (ESI) available: Crystallographic data of 2 and 3 in CIF, ESI-TOF-MS, UV-vis, ESR, DFT calculations, 1H NMR, and GC-MS data. CCDC 1017025 and 1017026. See DOI: 10.1039/c4sc02285h Click here for additional data file.

PubMed Central

Kaida, Suzue; Ishizuka, Tomoya; Sakaguchi, Miyuki; Ogura, Takashi; Shiota, Yoshihito; Yoshizawa, Kazunari

2015-01-01

A mononuclear Cr(v)–oxo complex, [CrV(O)(6-COO–-tpa)](BF4)2 (1; 6-COO–-tpa = N,N-bis(2-pyridylmethyl)-N-(6-carboxylato-2-pyridylmethyl)amine) was prepared through the reaction of a Cr(iii) precursor complex with iodosylbenzene as an oxidant. Characterization of 1 was achieved using ESI-MS spectrometry, electron paramagnetic resonance, UV-vis, and resonance Raman spectroscopies. The reduction potential (E red) of 1 was determined to be 1.23 V vs. SCE in acetonitrile based on analysis of the electron-transfer (ET) equilibrium between 1 and a one-electron donor, [RuII(bpy)3]2+ (bpy = 2,2′-bipyridine). The reorganization energy (λ) of 1 was also determined to be 1.03 eV in ET reactions from phenol derivatives to 1 on the basis of the Marcus theory of ET. The smaller λ value in comparison with that of an Fe(iv)–oxo complex (2.37 eV) is caused by the small structural change during ET due to the dπ character of the electron-accepting LUMO of 1. When benzyl alcohol derivatives (R-BA) with different oxidation potentials were employed as substrates, corresponding aldehydes were obtained as the 2e–-oxidized products in moderate yields as determined from 1H NMR and GC-MS measurements. One-step UV-vis spectral changes were observed in the course of the oxidation reactions of BA derivatives by 1 and a kinetic isotope effect (KIE) was observed in the oxidation reactions for deuterated BA derivatives at the benzylic position as substrates. These results indicate that the rate-limiting step is a concerted proton-coupled electron transfer (PCET) from substrate to 1. In sharp contrast, in the oxidation of trimethoxy-BA (E ox = 1.22 V) by 1, trimethoxy-BA radical cation was observed by UV-vis spectroscopy. Thus, it was revealed that the mechanism of the oxidation reaction changed from one-step PCET to stepwise ET–proton transfer (ET/PT), depending on the redox potentials of R-BA. PMID:29560181

The whole is more than the sum of its parts: Added value from a Graduate School as a structuring element within the wider field of early and pre-career support

NASA Astrophysics Data System (ADS)

Hanfland, Claudia; Sprengel, Claudia

2015-04-01

Structured postgraduate programs are a relatively new feature at German Higher Educational Institutions, mainly fostered in the 90ies by the funding programs of the German Science Foundation (Research Training Groups) and the Max-Planck-Association (International Max Planck Research Schools). Since then, funding opportunities for postgraduate programs have equally been set up by the Helmholtz and Leibniz Associations as well as the Excellence Initiative. Today, doctoral candidates can chose from a wide range of training programs to earn a doctoral degree within a structured framework under excellent research conditions. In consequence, the percentage of PhD students in natural sciences that follow a PhD within a structured program has been continuously increasing. Graduate Schools provide a roof under which different curricula can be accommodated. They offer a comprehensive training program, foster interdisciplinary thinking and are a key instrument for quality assurance by providing rules relevant and equal to all doctoral candidates regardless of funding or affiliation. With more and more Graduate Schools becoming a permanent feature in the training of doctoral candidates, universities and research institutions are provided with a tool to create added value for the whole range of early career scientists and beyond. The Alfred Wegener Institute for Polar and Marine Research (AWI) is currently developing a comprehensive strategy for early and pre-career support with the aim to provide a continuous support chain from high school students to Postdocs. Included are also the apprentices that get a vocational training at AWI as laboratory assistants, office clerks or qualified IT specialists. AWI aims at establishing a solid training network between these groups (apprentices, high school students, Bc and Ms students, internships, doctoral candidates, and Postdocs) across biographic borders. This network serves more than the classical transition phases from high school to university student, from Master to PhD students or from PhD student to Postdoc. Apprentices are integrated in research projects and supervised by PhD students. The former get a hands-on training in sample processing under realistic conditions, while the latter get support in mastering large sample sets. AWI's high school cooperation HIGHSEA offers a playground to gain teaching and supervising experience for PhD students and Postdocs (see talk by S. Gatti, same session). Within this career development network, AWI's Graduate School POLMAR acts as a nodal point to serve the interconnections, be it alongside the biographical chain or cross-sectoral in nature. POLMAR facilitates the networking and provides a structure in which partnerships with doctoral candidates can be carried out. To conclude, Graduate Schools can do more than improving the situation of doctoral candidates. In the best case, they become an integral part of an institute's career strategy and represent a point where new connections between biographical status groups get established for the benefit of all.

From Atmospheric Scientist to Data Scientist

NASA Astrophysics Data System (ADS)

Knuth, S. L.

2015-12-01

Most of my career has been spent analyzing data from research projects in the atmospheric sciences. I spent twelve years researching boundary layer interactions in the polar regions, which included five field seasons in the Antarctic. During this time, I got both a M.S. and Ph.D. in atmospheric science. I learned most of my data science and programming skills throughout this time as part of my research projects. When I graduated with my Ph.D., I was looking for a new and fresh opportunity to enhance the skills I already had while learning more advanced technical skills. I found a position at the University of Colorado Boulder as a Data Research Specialist with Research Computing, a group that provides cyber infrastructure services, including high-speed networking, large-scale data storage, and supercomputing, to university students and researchers. My position is the perfect merriment between advanced technical skills and "softer" skills, while at the same time understanding exactly what the busy scientist needs to understand about their data. I have had the opportunity to help shape our university's data education system, a development that is still evolving. This presentation will detail my career story, the lessons I have learned, my daily work in my new position, and some of the exciting opportunities that opened up in my new career.

STS-103 Pilot Kelly and MS Clervoy and Smith DEPART PAFB for Houston

NASA Technical Reports Server (NTRS)

1999-01-01

STS-103 Pilot Scott J. Kelly holds his daughter as he talks to Mission Specialists and fellow crew members Jean-Frangois Clervoy of France and Steven L. Smith on the runway at Patrick Air Force Base in Cocoa Beach, Fla. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Commander Curtis L. Brown Jr. and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

Firing back: how great leaders rebound after career disasters.

PubMed

Sonnenfeld, Jeffrey A; Ward, Andrew J

2007-01-01

Among the tests of a leader, few are more challenging-and more painful-than recovering from a career catastrophe. Most fallen leaders, in fact, don't recover. Still, two decades of consulting experience, scholarly research, and their own personal experiences have convinced the authors that leaders can triumph over tragedy--if they do so deliberately. Great business leaders have much in common with the great heroes of universal myth, and they can learn to overcome profound setbacks by thinking in heroic terms. First, they must decide whether or not to fight back. Either way, they must recruit others into their battle. They must then take steps to recover their heroic status, in the process proving, both to others and to themselves, that they have the mettle necessary to recover their heroic mission. Bernie Marcus exemplifies this process. Devastated after Sandy Sigoloff ired him from Handy Dan, Marcus decided to forgo the distraction of litigation and instead make the marketplace his batttleground. Drawing from his network of carefully nurtured relationships with both close and more distant acquaintances, Marcus was able to get funding for a new venture. He proved that he had the mettle, and recovered his heroic status, by building Home Depot, whose entrepreneurial spirit embodied his heroic mission. As Bank One's Jamie Dimon, J.Crew's Mickey Drexler, and even Jimmy Carter, Martha Stewart, and Michael Milken have shown, stunning comebacks are possible in all industries and walks of life. Whatever the cause of your predicament, it makes sense to get your story out. The alternative is likely to be long-lasting unemployment. If the facts of your dismissal cannot be made public because they are damning, then show authentic remorse. The public is often enormously forgiving when it sees genuine contrition and atonement.

Award for Distinguished Contributions to the International Advancement of Psychology.

PubMed

2016-11-01

This award is given to individuals who have made sustained and enduring contributions to international cooperation and the advancement of knowledge in psychology. The 2016 recipient of the APA Award for Distinguished Contributions to the International Advancement of Psychology was selected by the 2015 Committee on International Relations in Psychology (CIRP). The members of the 2015 CIRP were Rehman Abdulrehman, PhD (Chair); Gonzalo Bacigalupe, EdD; Silvia S. Canetto, PhD; Amanda Clinton, PhD; Melissa L. Morgan Consoli, PhD; Chryse G. Hatzichristou, PhD; Arpana G. Inman, PhD; Lori Foster Thompson, PhD; and Danny Wedding, PhD. Dr. Abdulrehman, Dr. Morgan Consoli, Dr. Thompson, and Dr. Wedding were members of the subcommittee for the 2016 award. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

PHD3-mediated prolyl hydroxylation of nonmuscle actin impairs polymerization and cell motility

PubMed Central

Luo, Weibo; Lin, Benjamin; Wang, Yingfei; Zhong, Jun; O'Meally, Robert; Cole, Robert N.; Pandey, Akhilesh; Levchenko, Andre; Semenza, Gregg L.

2014-01-01

Actin filaments play an essential role in cell movement, and many posttranslational modifications regulate actin filament assembly. Here we report that prolyl hydroxylase 3 (PHD3) interacts with nonmuscle actin in human cells and catalyzes hydroxylation of actin at proline residues 307 and 322. Blocking PHD3 expression or catalytic activity by short hairpin RNA knockdown or pharmacological inhibition, respectively, decreased actin prolyl hydroxylation. PHD3 knockdown increased filamentous F-actin assembly, which was reversed by PHD3 overexpression. PHD3 knockdown increased cell velocity and migration distance. Inhibition of PHD3 prolyl hydroxylase activity by dimethyloxalylglycine also increased actin polymerization and cell migration. These data reveal a novel role for PHD3 as a negative regulator of cell motility through posttranslational modification of nonmuscle actins. PMID:25079693

Repressive Tolerance and the Practice of Adult Education

ERIC Educational Resources Information Center

Brookfield, Stephen D.

2014-01-01

Herbert Marcuse's concept of repressive tolerance argues that behind the justification of tolerance lies the possibility of ideological domination. Tolerance allows intolerable practices to go unchallenged and flattens discussion to assume all viewpoints have equal validity. When alternative, dissenting views are inserted into the curriculum…

The Good Fight: from Plessy to Brown.

ERIC Educational Resources Information Center

Quarles, Benjamin

1979-01-01

The work of Black leaders and organizations from 1896 to 1954 is reviewed. Discussed are Booker T. Washington, W.E.B. DuBois, the NAACP, the National Urban League, Marcus Garvey, Arthur A. Schomberg, Carter G. Woodson, Charles S. Johnson, and A. Philip Randolph. (MC)

Chemistry Research of Optical Fibers.

DTIC Science & Technology

1982-09-27

BROADENING IN OPTICAL FIBERS Herbert B. Rosenstock* Naval Research Laboratory Washington, DC 20375 ABSTRACT A light pulse transmitted through a fiber...Marcatili, Marcuse , and Personick, "Dispersion Properties of Fibers" (Ch. 4 in "Optical Fiber Telecommunications," S. E. Miller and A. C. Chynoweth, eds

Tuning the driving force for exciton dissociation in single-walled carbon nanotube heterojunctions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ihly, Rachelle; Mistry, Kevin S.; Ferguson, Andrew J.

2016-04-25

Understanding the kinetics and energetics of interfacial electron transfer in molecular systems is crucial for the development of a broad array of technologies, including photovoltaics, solar fuel systems and energy storage. The Marcus formulation for electron transfer relates the thermodynamic driving force and reorganization energy for charge transfer between a given donor/acceptor pair to the kinetics and yield of electron transfer. Here we investigated the influence of the thermodynamic driving force for photoinduced electron transfer (PET) between single-walled carbon nanotubes (SWCNTs) and fullerene derivatives by employing time-resolved microwave conductivity as a sensitive probe of interfacial exciton dissociation. For the firstmore » time, we observed the Marcus inverted region (in which driving force exceeds reorganization energy) and quantified the reorganization energy for PET for a model SWCNT/acceptor system. The small reorganization energies (about 130 meV, most of which probably arises from the fullerene acceptors) are beneficial in minimizing energy loss in photoconversion schemes.« less

Broadband calibration of the R/V Marcus G. Langseth four-string seismic sources

NASA Astrophysics Data System (ADS)

Tolstoy, M.; Diebold, J.; Doermann, L.; Nooner, S.; Webb, S. C.; Bohnenstiehl, D. R.; Crone, T. J.; Holmes, R. C.

2009-08-01

The R/V Marcus G. Langseth is the first 3-D seismic vessel operated by the U.S. academic community. With up to a four-string, 36-element source and four 6-km-long solid state hydrophone arrays, this vessel promises significant new insights into Earth science processes. The potential impact of anthropogenic sound sources on marine life is an important topic to the marine seismic community. To ensure that operations fully comply with existing and future marine mammal permitting requirements, a calibration experiment was conducted in the Gulf of Mexico in 2007-2008. Results are presented from deep (˜1.6 km) and shallow (˜50 m) water sites, obtained using the full 36-element (6600 cubic inches) seismic source. This array configuration will require the largest safety radii, and the deep and shallow sites provide two contrasting operational environments. Results show that safety radii and the offset between root-mean-square and sound exposure level measurements were highly dependent on water depth.

Disruption of hypoxia-inducible transcription factor-prolyl hydroxylase domain-1 (PHD-1-/-) attenuates ex vivo myocardial ischemia/reperfusion injury through hypoxia-inducible factor-1α transcription factor and its target genes in mice.

PubMed

Adluri, Ram Sudheer; Thirunavukkarasu, Mahesh; Dunna, Nageswara Rao; Zhan, Lijun; Oriowo, Babatunde; Takeda, Kotaro; Sanchez, Juan A; Otani, Hajime; Maulik, Gautam; Fong, Guo-Hua; Maulik, Nilanjana

2011-10-01

Hypoxia-inducible transcription factor (HIF)-prolyl hydroxylases domain (PHD-1-3) are oxygen sensors that regulate the stability of the HIFs in an oxygen-dependent manner. Suppression of PHD enzymes leads to stabilization of HIFs and offers a potential treatment option for many ischemic disorders, such as peripheral artery occlusive disease, myocardial infarction, and stroke. Here, we show that homozygous disruption of PHD-1 (PHD-1(-/-)) could facilitate HIF-1α-mediated cardioprotection in ischemia/reperfused (I/R) myocardium. Wild-type (WT) and PHD-1(-/-) mice were randomized into WT time-matched control (TMC), PHD-1(-/-) TMC (PHD1TMC), WT I/R, and PHD-1(-/-) I/R (PHD1IR). Isolated hearts from each group were subjected to 30 min of global ischemia followed by 2 h of reperfusion. TMC hearts were perfused for 2 h 30 min without ischemia. Decreased infarct size (35%±0.6% vs. 49%±0.4%) and apoptotic cardiomyocytes (106±13 vs. 233±21 counts/100 high-power field) were observed in PHD1IR compared to wild-type ischemia/reperfusion (WTIR). Protein expression of HIF-1α was significantly increased in PHD1IR compared to WTIR. mRNA expression of β-catenin (1.9-fold), endothelial nitric oxide synthase (1.9-fold), p65 (1.9-fold), and Bcl-2 (2.7-fold) were upregulated in the PHD1IR compared with WTIR, which was studied by real-time quantitative polymerase chain reaction. Further, gel-shift analysis showed increased DNA binding activity of HIF-1α and nuclear factor-kappaB in PHD1IR compared to WTIR. In addition, nuclear translocation of β-catenin was increased in PHD1IR compared with WTIR. These findings indicated that silencing of PHD-1 attenuates myocardial I/R injury probably by enhancing HIF-1α/β-catenin/endothelial nitric oxide synthase/nuclear factor-kappaB and Bcl-2 signaling pathway.

"Fort Valley State University Cooperative Developmental Energy Program: Broadening the Participation of Underrepresented Minorities in the Geosciences"

NASA Astrophysics Data System (ADS)

Crumbly, I.; Hodges, J.; Kar, A.; Rashidi, L.

2014-12-01

According to the American Geological Institute's Status of Recent Geoscience Graduates, 2014, underrepresented minorities (URMs) make up only 7%, 5%, and 2% of graduates at the BS/BA, MA/MS, and Ph.D levels, respectively. Recruiting academically-talented URMs to major in the geosciences instead of majoring in other fields such as medicine, law, business, or engineering is a major undertaking. Numerous factors may contribute as to why few URMs choose geoscience careers. To address the underrepresentation of URMs in the geosciences 1992, the Cooperative Developmental Energy Program (CDEP) of Fort Valley State University (FVSU) and the College of Geosciences at the University of Oklahoma (OU) implemented a 3 + 2 dual degree program specifically in geology and geophysics. Since 1992, FVSU-CDEP has added the University of Texas at Austin (2004), Pennsylvania State University (2005), University of Arkansas (2010), and the University of Nevada at Las Vegas (2015) as partners to offer degrees in geology and geophysics. The dual degree programs consist of students majoring in chemistry or mathematics at FVSU for the first three years and transferring to one of the above partnering universities for years four and five to major in geology or geophysics. Upon completion of the program, students receive a BS degree in chemistry or mathematics from FVSU and a BS degree in geology or geophysics from a partnering university. CDEP has been responsible for recruiting 33 URMs who have earned BS degrees in geology or geophysics. Females constitute 50% of the graduates which is higher than the national average. Also, 56% of these graduates have earned the MS degree and 6% have earned the Ph.D. Currently, 60% of these graduates are employed with oil and gas companies; 20% work for academia; 12% work for governmental agencies; 6 % are professionals with environmental firms; and 2% of the graduate's employment is unknown.

"Fort Valley State University Cooperative Developmental Energy Program: Broadening the Participation of Underrepresented Minorities in the Geosciences"

NASA Astrophysics Data System (ADS)

Crumbly, I.; Hodges, J.; Kar, A.; Rashidi, L.

2015-12-01

According to the American Geological Institute's Status of Recent Geoscience Graduates, 2014, underrepresented minorities (URMs) make up only 7%, 5%, and 2% of graduates at the BS/BA, MA/MS, and Ph.D levels, respectively. Recruiting academically-talented URMs to major in the geosciences instead of majoring in other fields such as medicine, law, business, or engineering is a major undertaking. Numerous factors may contribute as to why few URMs choose geoscience careers. To address the underrepresentation of URMs in the geosciences 1992, the Cooperative Developmental Energy Program (CDEP) of Fort Valley State University (FVSU) and the College of Geosciences at the University of Oklahoma (OU) implemented a 3 + 2 dual degree program specifically in geology and geophysics. Since 1992, FVSU-CDEP has added the University of Texas at Austin (2004), Pennsylvania State University (2005), University of Arkansas (2010), and the University of Nevada at Las Vegas (2015) as partners to offer degrees in geology and geophysics. The dual degree programs consist of students majoring in chemistry or mathematics at FVSU for the first three years and transferring to one of the above partnering universities for years four and five to major in geology or geophysics. Upon completion of the program, students receive a BS degree in chemistry or mathematics from FVSU and a BS degree in geology or geophysics from a partnering university. CDEP has been responsible for recruiting 33 URMs who have earned BS degrees in geology or geophysics. Females constitute 50% of the graduates which is higher than the national average. Also, 56% of these graduates have earned the MS degree and 6% have earned the Ph.D. Currently, 60% of these graduates are employed with oil and gas companies; 20% work for academia; 12% work for governmental agencies; 6 % are professionals with environmental firms; and 2% of the graduate's employment is unknown.

Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin

PubMed Central

Wu, Colleen; Rankin, Erinn B.; Castellini, Laura; Fernandez-Alcudia, Javier; LaGory, Edward L.; Andersen, Rebecca; Rhodes, Steven D.; Wilson, Tremika L.S.; Mohammad, Khalid S.; Castillo, Alesha B.; Guise, Theresa A.; Schipani, Ernestina

2015-01-01

The bone microenvironment is composed of niches that house cells across variable oxygen tensions. However, the contribution of oxygen gradients in regulating bone and blood homeostasis remains unknown. Here, we generated mice with either single or combined genetic inactivation of the critical oxygen-sensing prolyl hydroxylase (PHD) enzymes (PHD1–3) in osteoprogenitors. Hypoxia-inducible factor (HIF) activation associated with Phd2 and Phd3 inactivation drove bone accumulation by modulating osteoblastic/osteoclastic cross-talk through the direct regulation of osteoprotegerin (OPG). In contrast, combined inactivation of Phd1, Phd2, and Phd3 resulted in extreme HIF signaling, leading to polycythemia and excessive bone accumulation by overstimulating angiogenic–osteogenic coupling. We also demonstrate that genetic ablation of Phd2 and Phd3 was sufficient to protect ovariectomized mice against bone loss without disrupting hematopoietic homeostasis. Importantly, we identify OPG as a HIF target gene capable of directing osteoblast-mediated osteoclastogenesis to regulate bone homeostasis. Here, we show that coordinated activation of specific PHD isoforms fine-tunes the osteoblastic response to hypoxia, thereby directing two important aspects of bone physiology: cross-talk between osteoblasts and osteoclasts and angiogenic–osteogenic coupling. PMID:25846796

Talking Circles Promote Equitable Discourse

ERIC Educational Resources Information Center

Hung, Marcus

2015-01-01

Teachers facilitate math talk in the classroom, but introducing a structured discussion format called the "talking circle" can influence opportunities for equitable student participation. Drawing on his reflections over the 2013-14 academic year and reviewing his detailed teaching notes and lesson plans, Marcus Hung takes a close look at…

Education as Simulation Game: A Critical Hermeneutic.

ERIC Educational Resources Information Center

Palermo, James

1979-01-01

This paper examines a specific educational game called "Popcorn Factory." First, it gives a detailed description of the game, then shifts the description into a critical hermeneutical framework, analyzing the deep structures at work in the "Popcorn Factory" according to the theories of Freud and Marcuse. (Author/SJL)

Innovation and Creativity.

ERIC Educational Resources Information Center

1998

This document contains four papers from a symposium on innovation and creativity and their relationship to human resource development (HRD). "Intrapreneurial Programs and Their Impact on Sales, Profit, and Return to Investors" (Melissa H. Marcus, Dennis G. Tesolowski, Clinton H. Isbell) reports on a study in which 100 of 217 randomly…

Critical Thinking as Cultural-Historical Practice.

ERIC Educational Resources Information Center

Panofsky, Carolyn P.

1999-01-01

Explores critical thinking as it has been constructed in schooling and in dominant traditions of psychological theory, presenting a dialectical view of critical thinking suggested in the social and philosophical writings of critical theorists (e.g., Theodor Adorno and Herbert Marcuse) and supported by the sociohistorical or cultural-historical…

22. Photocopy of architectural drawing. (Original is in the collection ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. Photocopy of architectural drawing. (Original is in the collection of Richard F. McCann, Pasadena, CA.) Site Plan (Untitled). Dated May 3, 1934. Race Course for Mr. Joseph Gottstein, Washington Jockey Club. B. Marcus Priteca. - Longacres, 1621 Southwest Sixteenth Street, Renton, King County, WA

Publishing scientific papers based on Master's and Ph.D. theses from a small scientific community: case study of Croatian medical schools.

PubMed

Frković, Vedran; Skender, Tomislav; Dojćinović, Bojan; Bilić-Zulle, Lidija

2003-02-01

To evaluate publishing activity of medical doctors after they have obtained Master's or Ph.D. degree at the Rijeka and Zagreb University Schools of Medicine in Croatia, and establish the number of journal articles based on these theses. Data on Master's and Ph.D. theses defended at the Rijeka and Zagreb University Schools of Medicine in the 1990-1999 period were collected by hand-search of the archive. MEDLINE and Current Contents databases were searched for journal articles resulting from the theses. During the 10-year period, 1,535 Master's and 634 Ph.D. theses were defended at the Rijeka and Zagreb University Schools of Medicine (253 Master's and 138 Ph.D. theses from Rijeka and 1,282 Master's and 496 Ph.D. theses from Zagreb). There were 201 (14%) Master's and 218 (34%) Ph.D. theses that resulted in articles published in journals indexed in MEDLINE (13% of Master's and 11% of Ph.D. theses from Rijeka, and 14% of Master's and 41% of Ph.D. theses from Zagreb). Also, 97 (6%) Master's and 129 (20%) Ph.D. theses that resulted in articles published in Current Contents journals (8% of Master's and 6% of Ph.D. theses from Rijeka, and 6% of Master's and 24% of Ph.D. theses from Zagreb). There was no significant difference between the two Universities with respect to published articles based on Master's theses, but there were significantly more articles from Ph.D. theses in Zagreb (p<0.001). Most of the theses resulted in a single publication (95%), 19 (5%) in 2, and 2 in 3 publications. Out of all 453 journal articles, 31% were published in Croatian and 69% in international journals. Most Croatian Master's and Ph.D. theses are not made available to the scientific community. There should be more institutional effort directed at the stimulation of postgraduate students to publish their scientific work.

Psi Chi/APA Edwin B. Newman Graduate Research Award.

PubMed

2016-11-01

The Edwin B. Newman Graduate Research Award is sponsored jointly by Psi Chi, the national honor society in psychology, and the APA. The award is presented annually to the psychology graduate student who submits the best research paper that was published or presented at a national, regional, or state psychological association conference during the past calendar year. The Edwin B. Newman Graduate Research Award is given jointly by Psi Chi and APA. Members of the 2016 Edwin B. Newman Award Committee were Shawn Carlton, PhD, Psi Chi representative; Christina Frederick-Recascino, PhD; John Norcross, PhD, APA representative; Karenna Malavanti, PhD, Psi Chi representative; Steven Kohn, PhD, Psi Chi representative; Warren Fass, PhD, Psi Chi representative; Chris Lovelace, PhD, Psi Chi representative; and Cathy Epkins, PhD, APA representative. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

International Humanitarian Award.

PubMed

2016-11-01

The International Humanitarian Award recognizes extraordinary humanitarian services and activism by psychologists, including professional and volunteer work conducted primarily in the field with underserved populations. Award recipients are psychologists who, by their extraordinary service at a difficult time, improve the lives and contribute to the well-being of people in a large or small geographic area anywhere in the world. The 2016 recipient of the APA International Humanitarian Award was selected by the 2015 Committee on International Relations in Psychology (CIRP). The members of the 2015 CIRP were Rehman Abdulrehman, PhD (Chair); Gonzalo Bacigalupe, EdD; Silvia S. Canetto, PhD; Amanda Clinton, PhD; Melissa L. Morgan Consoli, PhD; Chryse G. Hatzichristou, PhD; Arpana G. Inman, PhD; Lori Foster Thompson, PhD; and Danny Wedding, PhD. Dr. Abdulrehman, Dr. Morgan Consoli, Dr. Thompson, and Dr. Wedding were members of the subcommittee for the 2016 award. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Interaction Gaps in PhD Education and ICT as a Way Forward: Results from a Study in Sweden

ERIC Educational Resources Information Center

Aghaee, Naghmeh; Jobe, William Byron; Karunaratne, Thashmee; Smedberg, Åsa; Hansson, Henrik; Tedre, Matti

2016-01-01

Many research studies have highlighted the low completion rate and slow progress in PhD education. Universities strive to improve throughput and quality in their PhD education programs. In this study, the perceived problems of PhD education are investigated from PhD students' points of view, and how an Information and Communication Technology…

Collaborators | Center for Cancer Research

Cancer.gov

Collaborators Structural Biophysics Laboratory, CCR Macromolecular NMR Section (R. Andrew Byrd, Ph.D.) Protein-Nucleic Acid Interactions Section (Yun-Xing Wang, Ph.D.) Protein Processing Section (Kylie J. Walters, Ph.D.) Kinase Complexes Section (Ping Zhang, Ph.D.) Macromolecular Crystallography Laboratory, CCR

Disruption of Hypoxia-Inducible Transcription Factor-Prolyl Hydroxylase Domain-1 (PHD-1−/−) Attenuates Ex Vivo Myocardial Ischemia/Reperfusion Injury Through Hypoxia-Inducible Factor-1α Transcription Factor and Its Target Genes in Mice

PubMed Central

Adluri, Ram Sudheer; Thirunavukkarasu, Mahesh; Dunna, Nageswara Rao; Zhan, Lijun; Oriowo, Babatunde; Takeda, Kotaro; Sanchez, Juan A.; Otani, Hajime; Maulik, Gautam; Fong, Guo-Hua

2011-01-01

Abstract Hypoxia-inducible transcription factor (HIF)-prolyl hydroxylases domain (PHD-1–3) are oxygen sensors that regulate the stability of the HIFs in an oxygen-dependent manner. Suppression of PHD enzymes leads to stabilization of HIFs and offers a potential treatment option for many ischemic disorders, such as peripheral artery occlusive disease, myocardial infarction, and stroke. Here, we show that homozygous disruption of PHD-1 (PHD-1−/−) could facilitate HIF-1α-mediated cardioprotection in ischemia/reperfused (I/R) myocardium. Wild-type (WT) and PHD-1−/− mice were randomized into WT time-matched control (TMC), PHD-1−/− TMC (PHD1TMC), WT I/R, and PHD-1−/− I/R (PHD1IR). Isolated hearts from each group were subjected to 30 min of global ischemia followed by 2 h of reperfusion. TMC hearts were perfused for 2 h 30 min without ischemia. Decreased infarct size (35% ± 0.6% vs. 49% ± 0.4%) and apoptotic cardiomyocytes (106 ± 13 vs. 233 ± 21 counts/100 high-power field) were observed in PHD1IR compared to wild-type ischemia/reperfusion (WTIR). Protein expression of HIF-1α was significantly increased in PHD1IR compared to WTIR. mRNA expression of β-catenin (1.9-fold), endothelial nitric oxide synthase (1.9-fold), p65 (1.9-fold), and Bcl-2 (2.7-fold) were upregulated in the PHD1IR compared with WTIR, which was studied by real-time quantitative polymerase chain reaction. Further, gel-shift analysis showed increased DNA binding activity of HIF-1α and nuclear factor-kappaB in PHD1IR compared to WTIR. In addition, nuclear translocation of β-catenin was increased in PHD1IR compared with WTIR. These findings indicated that silencing of PHD-1 attenuates myocardial I/R injury probably by enhancing HIF-1α/β-catenin/endothelial nitric oxide synthase/nuclear factor-kappaB and Bcl-2 signaling pathway. Antioxid. Redox Signal. 15, 1789–1797. PMID:21083501

2017 JOSPT Award Recipients.

PubMed

Simoneau, Guy G

2018-05-01

During the American Physical Therapy Association's Combined Sections Meeting in New Orleans, LA in February 2018, JOSPT recognized the authors of the most outstanding research and clinical practice manuscripts published in JOSPT during 2017. The 2017 George J. Davies-James A. Gould Excellence in Clinical Inquiry Award was presented to Noa Ben-Ami, PT, PhD; Gabriel Chodick, MHA, PhD; Yigal Mirovsky, MD; Tamar Pincus, MPhil, MSc, PhD; and Yair Shapiro, MD, PhD, for their February 2017 article "Increasing Recreational Physical Activity in Patients With Chronic Low Back Pain: A Pragmatic Controlled Clinical Trial." The 2017 JOSPT Excellence in Research Award was presented to Sanneke Don, PT, MPT; Margot de Kooning, PT, PhD; Lennard Voogt, PT, MT, PhD; Kelly Ickmans, PT, PhD; Liesbeth Daenen, PT, PhD; and Jo Nijs, PT, MT, PhD, for their March 2017 article "The Effect of Visual Feedback of the Neck During Movement in People With Chronic Whiplash-Associated Disorders: An Experimental Study." J Orthop Sports Phys Ther 2018;48(5):348. doi:10.2519/jospt.2018.0104.

A fast ellipse extended target PHD filter using box-particle implementation

NASA Astrophysics Data System (ADS)

Zhang, Yongquan; Ji, Hongbing; Hu, Qi

2018-01-01

This paper presents a box-particle implementation of the ellipse extended target probability hypothesis density (ET-PHD) filter, called the ellipse extended target box particle PHD (EET-BP-PHD) filter, where the extended targets are described as a Poisson model developed by Gilholm et al. and the term "box" is here equivalent to the term "interval" used in interval analysis. The proposed EET-BP-PHD filter is capable of dynamically tracking multiple ellipse extended targets and estimating the target states and the number of targets, in the presence of clutter measurements, false alarms and missed detections. To derive the PHD recursion of the EET-BP-PHD filter, a suitable measurement likelihood is defined for a given partitioning cell, and the main implementation steps are presented along with the necessary box approximations and manipulations. The limitations and capabilities of the proposed EET-BP-PHD filter are illustrated by simulation examples. The simulation results show that a box-particle implementation of the ET-PHD filter can avoid the high number of particles and reduce computational burden, compared to a particle implementation of that for extended target tracking.

STS-89 M.S. Sharipov of the RSA participates in TCDT

NASA Technical Reports Server (NTRS)

1998-01-01

STS-89 Mission Specialist Salizhan Sharipov of the Russian Space Agency participates in a question and answer session for the media during Terminal Countdown Demonstration Test (TCDT) activities at KSC. The seven astronauts assigned to the eighth Shuttle-Mir docking flight are at KSC for this dress rehearsal for launch, which includes emergency egress training at the launch pad and culminates with a simulated countdown. The Space Shuttle Endeavour is undergoing preparations for liftoff, scheduled for Jan. 22. STS-89 Mission Specialist Andrew Thomas, Ph.D, will transfer to the Russian Space Station Mir, and succeed David Wolf, M.D., who will return to Earth aboard Endeavour. Dr. Thomas will live and work on Mir until June.

STS-89 M.S. Andrew Thomas waves to crowd during walkout

NASA Technical Reports Server (NTRS)

1998-01-01

STS-89 Mission Specialist Andrew Thomas, Ph.D., smiles and waves his Australian hat to the crowd outside of the Operations and Checkout Building at KSC as he heads toward the Astrovan that will transport him to Launch Pad 39A. There, the Space Shuttle Endeavour awaits to take the STS-89 crew to Russia's Mir space station, where Dr. Thomas, who was born and educated in South Australia, will succeed David Wolf, M.D. STS-89, slated for a 9:48 p.m. EST liftoff Jan. 22, is the eighth docking with the Russian Space Station Mir, the first Mir docking for Endeavour (all previous dockings were made by Atlantis), and the first launch of 1998.

STS-89 M.S. Andrew Thomas suits up

NASA Technical Reports Server (NTRS)

1998-01-01

STS-89 Mission Specialist Andrew Thomas, Ph.D., gives a 'thumbs up' as he completes the donning of his launch/entry suit in the Operations and Checkout (O&C) Building. In June 1995, he was named as payload commander for STS-77 and flew his first flight in space on Endeavour in May 1996. He and six fellow crew members will soon depart the O&C and head for Launch Pad 39A, where the Space Shuttle Endeavour will lift off during a launch window that opens at 9:43 p.m. EST, Jan. 22. STS-89 is the eighth of nine planned missions to dock the Space Shuttle with Russia's Mir space station, where Dr. Thomas will succeed David Wolf, M.D.

78 FR 56227 - Issuance of an Experimental Use Permit

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-12

... experimental use permit (EUP) to the pesticide applicant, Robert I. Rose, Ph.D., on behalf of James Mains, Ph.D.... Issuance. Robert I. Rose, Ph.D., on behalf of James Mains, Ph.D., Mosquito Mate, Inc., 1122 Oak Hill Drive...

The Added Value of a PhD in Medicine--PhD Students' Perceptions of Acquired Competences

ERIC Educational Resources Information Center

Anttila, Henrika; Lindblom-Ylänne, Sari; Lonka, Kristi; Pyhältö, Kirsi

2015-01-01

PhD in the field of medicine is more common than in any other domain. Many medical doctors are driven towards PhD, but also students with other backgrounds (usually MSc) are conducting a PhD in medical schools. Higher education has invested a lot in developing generic and research competences. Still little is known about how PhD students…

Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis

PubMed Central

Takeda, Yukiji; Costa, Sandra; Delamarre, Estelle; Roncal, Carmen; de Oliveira, Rodrigo Leite; Squadrito, Mario Leonardo; Finisguerra, Veronica; Deschoemaeker, Sofie; Bruyére, Françoise; Wenes, Mathias; Hamm, Alexander; Serneels, Jens; Magat, Julie; Bhattacharyya, Tapan; Anisimov, Andrey; Jordan, Benedicte F.; Alitalo, Kari; Maxwell, Patrick; Gallez, Bernard; Zhuang, Zhen W.; Saito, Yoshihiko; Simons, Michael; De Palma, Michele; Mazzone, Massimiliano

2015-01-01

PHD2 serves as an oxygen sensor that rescues blood supply by regulating vessel formation and shape in case of oxygen shortage1–5. However, it is unknown whether PHD2 can influence arteriogenesis. Here we studied the role of PHD2 in collateral artery growth by using hindlimb ischaemia as a model, a process that compensates for the lack of blood flow in case of major arterial occlusion6–8. We show that Phd2 (also known as Egln1) haplodeficient (Phd2+/−) mice displayed preformed collateral arteries that preserved limb perfusion and prevented tissue necrosis in ischaemia. Improved arteriogenesis in Phd2+/− mice was due to an expansion of tissue-resident, M2-like macrophages9,10 and their increased release of arteriogenic factors, leading to enhanced smooth muscle cell (SMC) recruitment and growth. Both chronic and acute deletion of one Phd2 allele in macrophages was sufficient to skew their polarization towards a proarteriogenic phenotype. Mechanistically, collateral vessel preconditioning relied on the activation of canonical NF-κB pathway in Phd2+/− macrophages. These results unravel how PHD2 regulates arteriogenesis and artery homeostasis by controlling a specific differentiation state in macrophages and suggest new treatment options for ischaemic disorders. PMID:21983962

The experience of disagreement between students and supervisors in PhD education: a qualitative study

PubMed Central

2013-01-01

Background PhD supervision is mostly individual and disagreement between supervisors and PhD students is a seldom-discussed topic at universities. The present study aimed to describe the experience of disagreement between PhD students and supervisors. Methods Nine supervisors and seven PhD students from Sweden and England were interviewed using a video recorder. The recorded material was analysed using inductive content analysis. Results Disagreements in PhD education can be described with the overarching theme: the nature of the disagreements changes over time. Five categories emerged to describe the variations of the experiences: involvement in important decisions, supervisors not being up-to-date, dubious advice from supervisors, mediating between supervisors, and interpersonal relationships. Conclusions There is a gradual shift in competence where PhD students may excel supervisors in subject knowledge. Early disagreements may indicate immaturity of the student while disagreements later may indicate that the student is maturing making their own decisions. Consequently, disagreements may need to be addressed differently depending on when they occur. Addressing them inappropriately might slow the progressions and result in higher attrition rate among PhD students. The five categories may be elements in future PhD supervisor training programs and should be further evaluated for their importance and impact on PhD education. PMID:24074051

Laser Spectroscopic Study on Oxygen Isotope Effects in Ozone Surface Decomposition

NASA Astrophysics Data System (ADS)

Minissale, Marco; Boursier, Corinne; Elandaloussi, Hadj; Te, Yao; Jeseck, Pascal; Rouille, Christian; Zanon-Willette, Thomas; Janssen, Christof

2016-04-01

The isotope kinetics of ozone formation in the Chapman reaction [1] O + O2 + M → O3 + M (1) provides the primary example for a chemically induced oxygen isotope anomaly and is associated with large [2] and mass independent [3] oxygen isotope enrichments in the product molecule, linked to a symmetry selection in the ozone formation kinetics [4-5]. The isotopic composition of ozone and its transfer to other molecules is a powerful tracer in the atmospheric and biogeochemical sciences [6] and serves as a primary model for a possible explanation of the oxygen isotopic heterogeneity in the Solar system [7-8]. Recently, the isotope fractionation in the photolytic decomposition process O3 + hν → O2 + O (2) using visible light has been studied in detail [9-10]. Much less is currently known about the isotope fractionation in the dry deposition or in the gas phase thermal decomposition of ozone O3 + M → O2 + O +M. (3) Here we report on first spectroscopic studies of non-photolytic ozone decomposition using a cw-quantum cascade laser at 9.5 μm. The concentration of individual ozone isotopomers (16O3,16O16O17O, and 16O17O16O) in a teflon coated reaction cell is followed in real time at temperatures between 25 and 150 °C. Observed ozone decay rates depend on homogeneous (reaction (3)) processes in the gas phase and on heterogeneous reactions on the wall. A preliminary analysis reveals agreement with currently recommended ozone decay rates in the gas phase and the absence of a large symmetry selection in the surface decomposition process, indicating the absence of a mass independent fractionation effect. This result is in agreement with previous mass spectrometer (MS) studies on heterogeneous ozone formation on pyrex [11], but contradicts an earlier MS study [12] on ozone surface decomposition on pyrex and quartz. Implications for atmospheric chemistry will be discussed. [1] Morton, J., Barnes, J., Schueler, B. and Mauersberger, K. J. Geophys. Res. 95, 901 - 907 (1990). [2] Mauersberger, K. Geophys. Res. Lett. 8, 935-937 (1981). [3] Thiemens, M. H. and Heidenreich, J. E. Science 219, 1073 - 1075 (1983). [4] Janssen, C., Guenther, J., Mauersberger, K. and Krankowsky, D. Phys. Chem. Chem. Phys. 3, 4718-4721 (2001). [5] Gao, Y. Q. and Marcus, R. A. Science 293, 259-263 (2001). [6] Brenninkmeijer, C. A. M. et al. Chem. Rev. 103, 5125 - 5162 (2003). [7] Thiemens, M. H. and Shaheen, in Treatise on Geochemistry, Holland H. and Turekian K. eds., 151 - 177 (2014). [8] Marcus, R. A. J. Chem. Phys. 121, 8201 - 8211 (2004). [9] Früchtl, M., Janssen, C. and Röckmann, T. J. Geophys. Res. Atmos. 120, 4398 - 4416 (2015). [10] Früchtl, M., Janssen, C., Taraborrelli, D., Gromov, S. and Röckmann, T. Geophys. Res. Lett. (2015). [11] Janssen, C. and Tuzson, B. J. Phys. Chem. A 114, 9709-9719 (2010). [12] Chakraborty, S. and Bhattacharya, S. K. Chem. Phys. Lett. 369, 662-667 (2003).

Regular Morphology and the Lexicon.

ERIC Educational Resources Information Center

Bybee, Joan

1995-01-01

This article compares three models of morphological storage and processing: (1) the dual-processing model of Pinker, Marcus and others; (2) the connectionist model of Marchman, Plunkett, Seidenberg, and others; and (3) the network model of Bybee and Langacker. Type frequency of a morphological pattern is shown to be important in determining…

Stability Analysis of Finite Difference Approximations to Hyperbolic Systems, and Problems in Applied and Computational Matrix Theory

DTIC Science & Technology

1988-07-08

Marcus and C. Baczynski), Computer Science Press, Rockville, Maryland, 1986. 3. An Introduction to Pascal and Precalculus , Computer Science Press...Science Press, Rockville, Maryland, 1986. 35. An Introduction to Pascal and Precalculus , Computer Science Press, Rockville, Maryland, 1986. 36

Understanding the Charter School Special Education Gap: Evidence from Denver, Colorado

ERIC Educational Resources Information Center

Winters, Marcus A.

2014-01-01

Center on Reinventing Public Education (CRPE) commissioned Dr. Marcus Winters to analyze the factors driving the special education gap between Denver's charter and traditional public elementary and middle schools. Using student-level data, Winters shows that Denver's special education enrollment gap starts at roughly 2 percentage points in…

2005 Armaments Technology Seminar and Exhibition

DTIC Science & Technology

2005-06-13

Carolina Sofer •Catina Crismale •Preparedness •Jason Emmel •Andrea Marcus •James Smith •Tim Phelan •Nikiesha Nicholas •Kathy Wioland •Mary Paczkowski • Jamie ...ASSESS PRI CATEGORY HPTs EFFECTS AGENCY ASSET AGENCY ASSET WHEN AGENCY ASSET 1 3 4 5 6 LAWTON Mayor Coop

The Perils of Repressive Tolerance in Music Education Curriculum

ERIC Educational Resources Information Center

Perrine, William M.

2017-01-01

In recent years, philosophers of music education have called for a greater degree of political engagement by music education practitioners. Using Marcuse's discussion of "repressive tolerance" as a conceptual framework, I argue that a politicized curriculum in music education works against the liberal ideas of free speech and a free…

Anarchism, Schooling, and Democratic Sensibility

ERIC Educational Resources Information Center

Kennedy, David

2017-01-01

This paper seeks to address the question of schooling for democracy by, first, identifying at least one form of social character, dependent, after Marcuse, on the historical emergence of a "new sensibility." It then explores one pedagogical thread related to the emergence of this form of subjectivity over the course of the last two…

An Archetypal Phenomenology of "Skholé"

ERIC Educational Resources Information Center

Kennedy, David

2017-01-01

In this essay David Kennedy argues that children represent one vanguard of an emergent shift in Western subjectivity, and that adult-child dialogue, especially in the context of schooling, is a key locus for the epistemological change that implies. Following Herbert Marcuse's invocation of a "new sensibility," Kennedy argues that the…

Approval of Alternative Test Method for Puerto Nuevo Wastewater Treatment Plant, San Juan, Puerto Rico Memorandum

EPA Pesticide Factsheets

This December 2008 memorandum is from Conniesue Oldham of the Measurement Technology Group to Marcus E. Kantz in EPA Region 2. This memorandum is regarding a request to use an alternative test method at the Puerto Neuvo wastewater treatment plant

Utopia and Education in Critical Theory

ERIC Educational Resources Information Center

Lewis, Tyson

2006-01-01

In this article the author examines the intimate connections between utopia and education in Frankfurt School critical theory. Although substantial links have been made in the critical pedagogy tradition between education, critique, and utopian dreaming, an in-depth analysis of the utopia-education matrix in the works of Herbert Marcuse, Theodor…

78 FR 49267 - Conflict of Interest Waiver

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-13

... FEDERAL COMMUNICATIONS COMMISSION Conflict of Interest Waiver AGENCY: Federal Communications Commission. ACTION: Notice of waiver of section 4(b) of the Communications Act of 1934. SUMMARY: Notice is... section 4(b) of the Communications Act of 1924, as amended, 47 U.S.C. 154(b), for Mr. Theodore Marcus...

22. Photocopy of architectural drawing. (Original is in the collection ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. Photocopy of architectural drawing. (Original is in the collection of Richard F. McCann, Pasadena, CA.) Grandstand Balcony Plan. Dated June 30, 1933. Race Course for Mr. Joseph Gottstein, Washington Jockey Club. B. Marcus Priteca. - Longacres, Original Grandstand, 1621 Southwest Sixteenth Street, Renton, King County, WA

Learning Non-Adjacent Regularities at Age 0 ; 7

ERIC Educational Resources Information Center

Gervain, Judit; Werker, Janet F.

2013-01-01

One important mechanism suggested to underlie the acquisition of grammar is rule learning. Indeed, infants aged 0 ; 7 are able to learn rules based on simple identity relations (adjacent repetitions, ABB: "wo fe fe" and non-adjacent repetitions, ABA: "wo fe wo", respectively; Marcus et al., 1999). One unexplored issue is…

National CrossTalk. Volume 12, Number 3, Summer 2004

ERIC Educational Resources Information Center

Trombley, William, Ed.

2004-01-01

The primary purpose of "National CrossTalk" is to stimulate informed discussion and debate of higher education issues. This issue contains the following articles: (1) U.K. Adopts "Top-Up" Tuition Fees: British Universities Prepare to Compete in a More "American" System (Jon Marcus); (2) "Plain Living": Berea…

National CrossTalk. Volume 15, Number 1, Winter 2007

ERIC Educational Resources Information Center

Trombley, William, Ed.

2007-01-01

The primary purpose of "National CrossTalk" is to stimulate informed discussion and debate of higher education issues. This issue contains the following articles: (1) The Celtic Tiger: Ireland Invests Heavily in Higher Education, and Benefits Mightily (Jon Marcus); (2) Western Classic: Nevada's James Rogers Is a Non-Traditional…

National CrossTalk. Volume 17, Number 1

ERIC Educational Resources Information Center

Trombley, William, Ed.

2009-01-01

The primary purpose of "National CrossTalk" is to stimulate informed discussion and debate of higher education issues. This issue contains the following articles: (1) Florida's Unnatural Disaster: The State's Economic Bubble Has Burst, Leaving Higher Education in a Double Bind (Jon Marcus); (2) Saudi King's Modern University:…

lcmodels

Cancer.gov

The R package provides individual risks of lung cancer and lung cancer death based on various published papers: Bach et al., 2003; Spitz et al., 2007; Cassidy et al., 2008 (LLP); Hoggart et al., 2012; Tammemagi et al., 2013; Marcus et al., 2015 (LLPi); Wilson and Weissfeld, 2015 (Pittsburgh); Katki et al., 2016 (LCRAT and LCDRAT)

The NMC Horizon Report: 2013 Museum Edition

ERIC Educational Resources Information Center

Johnson, L.; Adams Becker, S.; Freeman, A.

2013-01-01

The "NMC Horizon Report: 2013 Museum Edition," is a co-production with the Marcus Institute for Digital Education in the Arts (MIDEA), and examines six emerging technologies for their potential impact on and use in education and interpretation within the museum environment: BYOD (Bring Your Own Device), crowdsourcing, electronic…

Gifted Sixth-Graders and Primary Source Philosophy.

ERIC Educational Resources Information Center

White, David A.; Schlaggar, Sheila

1993-01-01

A sixth-grade gifted class studied the history of philosophy, including selections from such philosophers as Plato, Confucius, Buddha, Marcus Aurelius, and Moses Maimonides. Readings drew on fundamental features of child experience, such as their sense of justice, concern for moral values, and questions about reality. The paper describes classroom…

Biomedical PhD education--an international perspective.

PubMed

Mulvany, Michael J

2013-05-01

The PhD, otherwise known as the doctor of philosophy or Dr. Phil., is an internationally recognized degree, indicating that the PhD graduate has received training in research under supervision. Traditionally, the PhD was the route to an academic career, with most successful PhD graduates receiving tenured university positions. However, over the past 20-30 years, and particularly the past 10 years, the situation has changed dramatically. Governments in many countries have invested massively in PhD education, believing that trained researchers will contribute to the 'knowledge society', and thus increase the competitiveness of their countries in the future economies of the world. Thus, only a small fraction of PhD graduates now end up in academic research. Yet, the PhD remains a research degree, and indeed, institutions have become heavily dependent on PhD students for their research output. The situation has thus created a paradox. On the one hand, it has become essential for institutions to have many PhD students and for the research performed to be of the highest level. On the other hand, the careers of PhD students are not necessarily going to be directly related to the research performed during their PhD studies. The purpose of this article is to explore how this seeming paradox is being addressed in biomedicine and to show that far from being inconsistent that the two aspects are in fact complementary. The article is based on the author's experience as Head of Aarhus Graduate School of Health Sciences 2002-2011 and his work with graduate schools across Europe and internationally through the organization ORPHEUS. © 2013 Nordic Pharmacological Society. Published by Blackwell Publishing Ltd.

Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR

PubMed Central

Henze, Anne-Theres; Garvalov, Boyan K.; Seidel, Sascha; Cuesta, Angel M.; Ritter, Mathias; Filatova, Alina; Foss, Franziska; Dopeso, Higinio; Essmann, Clara L.; Maxwell, Patrick H.; Reifenberger, Guido; Carmeliet, Peter; Acker-Palmer, Amparo; Acker, Till

2014-01-01

Solid tumours are exposed to microenvironmental factors such as hypoxia that normally inhibit cell growth. However, tumour cells are capable of counteracting these signals through mechanisms that are largely unknown. Here we show that the prolyl hydroxylase PHD3 restrains tumour growth in response to microenvironmental cues through the control of EGFR. PHD3 silencing in human gliomas or genetic deletion in a murine high-grade astrocytoma model markedly promotes tumour growth and the ability of tumours to continue growing under unfavourable conditions. The growth-suppressive function of PHD3 is independent of the established PHD3 targets HIF and NF-κB and its hydroxylase activity. Instead, loss of PHD3 results in hyperphosphorylation of epidermal growth factor receptor (EGFR). Importantly, epigenetic/genetic silencing of PHD3 preferentially occurs in gliomas without EGFR amplification. Our findings reveal that PHD3 inactivation provides an alternative route of EGFR activation through which tumour cells sustain proliferative signalling even under conditions of limited oxygen availability. PMID:25420773

APA/APAGS Award for Distinguished Graduate Student in Professional Psychology.

PubMed

2016-11-01

The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded on an annual basis by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. A qualified candidate must demonstrate exemplary performance in working with an underserved population in an applied setting or have developed an innovative method for delivering health services to an underserved population. The 2016 recipient of the APA/APAGS Award for Distinguished Graduate Student in Professional Psychology was selected by the 2015 Board of Professional Affairs (BPA) and the 2015 APAGS Scholarship and Awards Selection Committee. Members of the 2015 BPA were Patricia Arredondo, EdD; Helen L. Coons, PhD, ABPP; Vickie Mays, PhD, MSPH; Linda A. Reddy, PhD; Lois O. Condi, PhD; Antonette M. Zeiss, PhD; Timothy A. Cavell, PhD; Robert T. Kinscherff, PhD, JD; and Jared L. Skillings, PhD, ABPP. Members of the 2015 APAGS Scholarship and Awards Selection Committee were Emily Voelkel, PhD; Blaire Schembari; and Yolanda Perkins-Volk. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility.

PubMed

Astuti, Dewi; Ricketts, Christopher J; Chowdhury, Rasheduzzaman; McDonough, Michael A; Gentle, Dean; Kirby, Gail; Schlisio, Susanne; Kenchappa, Rajappa S; Carter, Bruce D; Kaelin, William G; Ratcliffe, Peter J; Schofield, Christopher J; Latif, Farida; Maher, Eamonn R

2011-02-01

Germline mutations in the von Hippel-Lindau disease (VHL) and succinate dehydrogenase subunit B (SDHB) genes can cause inherited phaeochromocytoma and/or renal cell carcinoma (RCC). Dysregulation of the hypoxia-inducible factor (HIF) transcription factors has been linked to VHL and SDHB-related RCC; both HIF dysregulation and disordered function of a prolyl hydroxylase domain isoform 3 (PHD3/EGLN3)-related pathway of neuronal apoptosis have been linked to the development of phaeochromocytoma. The 2-oxoglutarate-dependent prolyl hydroxylase enzymes PHD1 (EGLN2), PHD2 (EGLN1) and PHD3 (EGLN3) have a key role in regulating the stability of HIF-α subunits (and hence expression of the HIF-α transcription factors). A germline PHD2 mutation has been reported in association with congenital erythrocytosis and recurrent extra-adrenal phaeochromocytoma. We undertook mutation analysis of PHD1, PHD2 and PHD3 in two cohorts of patients with features of inherited phaeochromocytoma (n=82) and inherited RCC (n=64) and no evidence of germline mutations in known susceptibility genes. No confirmed pathogenic mutations were detected suggesting that mutations in these genes are not a frequent cause of inherited phaeochromocytoma or RCC.

APA/APAGS Award for Distinguished Graduate Student in Professional Psychology.

PubMed

2017-12-01

The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded on an annual basis by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. A qualified candidate must demonstrate exemplary performance in working with an underserved population in an applied setting or have developed an innovative method for delivering health services to an underserved population. The 2017 recipient of the APA/APAGS Award for Distinguished Graduate Student in Professional Psychology was selected by the 2016 Board of Professional Affairs (BPA) and the 2016 APAGS Scholarship and Awards Selection Committee. Members of the 2016 BPA were Antonette M. Zeiss, PhD (Chair); Linda A. Reddy, PhD; Lois O. Condie, PhD; Timothy A. Cavell, PhD; Robert T. Kinscherff, PhD, JD; Jared L. Skillings, PhD, ABPP; Cynthia A. Gómez, PhD; Lisa K. Kearney, PhD, ABPP; and Dinelia Rosa, PhD. Members of the 2016 APAGS Scholarship and Awards Selection Committee were Jerrold Yeo, MA; Jacklynn Fitzgerald, MA; and Roseann Fish Getchell, MA, Med. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Characterization of NF1 Protein Ubiquitination

DTIC Science & Technology

2008-06-01

Ubiquitination PRINCIPAL INVESTIGATOR: Koko Murakami, Ph.D. Victor A Fried, Ph.D. CONTRACTING ORGANIZATION: New York Medical College...NUMBER W81XWH-07-1-0432 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Koko Murakami, Ph.D.; Victor A Fried, Ph.D. 5d. PROJECT NUMBER 5e. TASK

Strategic Studies Quarterly. Volume 8, Number 1, Spring 2014

DTIC Science & Technology

2014-01-01

Charles E. Costanzo, PhD Christopher M. Hemmer, PhD Kimberly A. Hudson, PhD Nori Katagiri, PhD Zachary J . Zwald, PhD Strategic Studies Quarterly (SSQ...first successful carrier-based takeoff and landing with the Jian-15 ( J -15) in November 2012, certified its first group of aircraft carrier pilots and...September 2013.3 The Liaoning will continue to conduct short deployments and shipboard aviation training until 2015 to 2016, when China’s first J -15

Field implementation of fiber-reinforced polymer (FRP) deck panels.

DOT National Transportation Integrated Search

2017-06-01

Jeffery S. Volz, S.E., P.E., Ph.D., Kamal H. Khayat, PhD, P.Eng. http://orcid.org/0000-0003-1431-0715, Soo Duck Hwang, Ph.D. http://orcid.org/0000-0003-2178-1531, Hesham Tuwair, Ph.D., Jonathan T. Drury, Amy S. Crone : Although still in their infancy...

STS-103 MS Clervoy tries on oxygen mask

NASA Technical Reports Server (NTRS)

1999-01-01

In the bunker at Launch Pad 39B, STS-103 Mission Specialist Jean-Frangois Clervoy of France, who is with the European Space Agency (ESA), tries on an oxygen mask during Terminal Countdown Demonstration Test (TCDT) activities. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. Other crew members taking part are Commander Curtis L. Brown Jr. and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), plus Claude Nicollier of Switzerland, who is also with ESA. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

STS-93 M.S. Tognini and Commander Collins take part in emergency egress training

NASA Technical Reports Server (NTRS)

1999-01-01

During emergency egress training inside an M-113 armored personnel carrier at the launch pad, Mission Specialist Michel Tognini of France and Commander Eileen M. Collins share a light moment. In preparation for their mission, the STS-93 crew are participating in Terminal Countdown Demonstration Test activities that also include a launch-day dress rehearsal culminating with a simulated main engine cut-off. Also at KSC are Pilot Jeffrey S. Ashby and Mission Specialists Steven A. Hawley (Ph.D.), and Catherine G. Coleman (Ph.D.). Collins is the first woman to serve as mission commander. Tognini represents the Centre National d'Etudes Spatiales (CNES). The primary mission of STS-93 is the release of the Chandra X-ray Observatory, which will allow scientists from around the world to obtain unprecedented X-ray images of exotic environments in space to help understand the structure and evolution of the universe. Chandra is expected to provide unique and crucial information on the nature of objects ranging from comets in our solar system to quasars at the edge of the observable universe. Since X-rays are absorbed by the Earth's atmosphere, space-based observatories are necessary to study these phenomena and allow scientists to analyze some of the greatest mysteries of the universe. The targeted launch date for STS-93 is no earlier than July 20 at 12:36 a.m. EDT from Launch Pad 39B.

Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism.

PubMed

Quaegebeur, Annelies; Segura, Inmaculada; Schmieder, Roberta; Verdegem, Dries; Decimo, Ilaria; Bifari, Francesco; Dresselaers, Tom; Eelen, Guy; Ghosh, Debapriva; Davidson, Shawn M; Schoors, Sandra; Broekaert, Dorien; Cruys, Bert; Govaerts, Kristof; De Legher, Carla; Bouché, Ann; Schoonjans, Luc; Ramer, Matt S; Hung, Gene; Bossaert, Goele; Cleveland, Don W; Himmelreich, Uwe; Voets, Thomas; Lemmens, Robin; Bennett, C Frank; Robberecht, Wim; De Bock, Katrien; Dewerchin, Mieke; Ghesquière, Bart; Fendt, Sarah-Maria; Carmeliet, Peter

2016-02-09

The oxygen-sensing prolyl hydroxylase domain proteins (PHDs) regulate cellular metabolism, but their role in neuronal metabolism during stroke is unknown. Here we report that PHD1 deficiency provides neuroprotection in a murine model of permanent brain ischemia. This was not due to an increased collateral vessel network. Instead, PHD1(-/-) neurons were protected against oxygen-nutrient deprivation by reprogramming glucose metabolism. Indeed, PHD1(-/-) neurons enhanced glucose flux through the oxidative pentose phosphate pathway by diverting glucose away from glycolysis. As a result, PHD1(-/-) neurons increased their redox buffering capacity to scavenge oxygen radicals in ischemia. Intracerebroventricular injection of PHD1-antisense oligonucleotides reduced the cerebral infarct size and neurological deficits following stroke. These data identify PHD1 as a regulator of neuronal metabolism and a potential therapeutic target in ischemic stroke. Copyright © 2016 Elsevier Inc. All rights reserved.

What Took Them So Long? Explaining PhD Delays among Doctoral Candidates

PubMed Central

van de Schoot, Rens; Yerkes, Mara A.; Mouw, Jolien M.; Sonneveld, Hans

2013-01-01

A delay in PhD completion, while likely undesirable for PhD candidates, can also be detrimental to universities if and when PhD delay leads to attrition/termination. Termination of the PhD trajectory can lead to individual stress, a loss of valuable time and resources invested in the candidate and can also mean a loss of competitive advantage. Using data from two studies of doctoral candidates in the Netherlands, we take a closer look at PhD duration and delay in doctoral completion. Specifically, we address the question: Is it possible to predict which PhD candidates will experience delays in the completion of their doctorate degree? If so, it might be possible to take steps to shorten or even prevent delay, thereby helping to enhance university competitiveness. Moreover, we discuss practical do's and don'ts for universities and graduate schools to minimize delays. PMID:23935895

DELETION OR INHIBITION OF THE OXYGEN SENSOR PHD1 PROTECTS AGAINST ISCHEMIC STROKE VIA REPROGRAMMING OF NEURONAL METABOLISM

PubMed Central

Quaegebeur, Annelies; Segura, Inmaculada; Schmieder, Roberta; Verdegem, Dries; Decimo, Ilaria; Bifari, Francesco; Dresselaers, Tom; Eelen, Guy; Ghosh, Debapriva; Schoors, Sandra; Janaki Raman, Sudha Rani; Cruys, Bert; Govaerts, Kristof; De Legher, Carla; Bouché, Ann; Schoonjans, Luc; Ramer, Matt S.; Hung, Gene; Bossaert, Goele; Cleveland, Don W.; Himmelreich, Uwe; Voets, Thomas; Lemmens, Robin; Bennett, C. Frank; Robberecht, Wim; De Bock, Katrien; Dewerchin, Mieke; Fendt, Sarah-Maria; Ghesquière, Bart; Carmeliet, Peter

2016-01-01

Summary The oxygen-sensing prolyl hydroxylase domain proteins (PHDs) regulate cellular metabolism, but their role in neuronal metabolism during stroke is unknown. Here we report that PHD1 deficiency provides neuroprotection in a murine model of permanent brain ischemia. This was not due to an increased collateral vessel network, nor to enhanced neurotrophin expression. Instead, PHD1−/− neurons were protected against oxygen-nutrient deprivation by reprogramming glucose metabolism. Indeed, PHD1−/− neurons enhanced glucose flux through the oxidative pentose phosphate pathway by diverting glucose from glycolysis. As a result, PHD1−/− neurons increased their redox buffering capacity to scavenge oxygen radicals in ischemia. Intracerebroventricular injection of PHD1-antisense oligonucleotides reduced the cerebral infarct size and neurological deficits following stroke. These data identify PHD1 as a novel regulator of neuronal metabolism and a potential therapeutic target in ischemic stroke. PMID:26774962

CLONING, EXPRESSION, AND MUTATIONAL ANALYSIS OF RAT S-ADENOSYL-1-METHIONINE: ARSENIC (III) METHYLTRANSFERASE

EPA Science Inventory

CLONING, EXPRESSION, AND MUTATIONAL ANALYSIS OF RAT
S-ADENOSYL-L-METHIONINE: ARSENIC(III) METHYLTRANSFERASE

Stephen B. Waters, Ph.D., Miroslav Styblo, Ph.D., Melinda A. Beck, Ph.D., University of North Carolina at Chapel Hill; David J. Thomas, Ph.D., U.S. Environmental...

78 FR 17207 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-20

.... 20130471 G Sun Pharmaceutical Industries Limited; Takeda Pharmaceutical Company Limited; Sun Pharmaceutical.... Martin, Ph.D.; Gilead Sciences, Inc.; John C. Martin, Ph.D. 20130547 G Jindal Poly Films Limited; Exxon... Norbert W. Bischofberger, Ph.D.; Gilead Sciences, Inc.; Norbert W. Bischofberger, Ph.D. 20130611 G...

A Multiattributes Approach for Ranking PhD Programs

ERIC Educational Resources Information Center

Urbancic, Frank R.

2008-01-01

In its plan to combat the PhD shortage crisis, the Association to Advance Collegiate Schools of Business International (AACSB; 2003) has called for the development of PhD program rankings to serve as incentives for academic institutions to invest more in PhD programs, thereby counterbalancing the disproportionate influence of master of business…

Prolyl-4-hydroxylase domain 3 (PHD3) is a critical terminator for cell survival of macrophages under stress conditions.

PubMed

Swain, Lija; Wottawa, Marieke; Hillemann, Annette; Beneke, Angelika; Odagiri, Haruki; Terada, Kazutoyo; Endo, Motoyoshi; Oike, Yuichi; Farhat, Katja; Katschinski, Dörthe M

2014-09-01

On a molecular level, cells sense changes in oxygen availability through the PHDs, which regulate the protein stability of the α-subunit of the transcription factor HIF. Especially, PHD3 has been additionally associated with apoptotic cell death. We hypothesized that PHD3 plays a role in cell-fate decisions in macrophages. Therefore, myeloid-specific PHD3(-/-) mice were created and analyzed. PHD3(-/-) BMDM showed no altered HIF-1α or HIF-2α stabilization or increased HIF target gene expression in normoxia or hypoxia. Macrophage M1 and M2 polarization was unchanged likewise. Compared with macrophages from WT littermates, PHD3(-/-) BMDM exhibited a significant reduction in TUNEL-positive cells after serum withdrawal or treatment with stauro and SNAP. Under the same conditions, PHD3(-/-) BMDM also showed less Annexin V staining, which is representative for membrane disruption, and indicated a reduced early apoptosis. In an unbiased transcriptome screen, we found that Angptl2 expression was reduced in PHD3(-/-) BMDM under stress conditions. Addition of rAngptl2 rescued the antiapoptotic phenotype, demonstrating that it is involved in the PHD3-mediated response toward apoptotic stimuli in macrophages. © 2014 Society for Leukocyte Biology.

Disrupting Myths of Poverty in the Face of Resistance

ERIC Educational Resources Information Center

Pollock, Katina; Lopez, Ann; Joshee, Reva

2013-01-01

This case disrupts some of the prevalent myths about families from low-income and poor households held by educators. Recognizing the inherent tensions, this case demonstrates the importance of creating equitable and inclusive learning environments. We presented some of the challenges faced by Marcus, a progressive principal, as he attempts to…

Re-Imagining Spaces, Collectivity, and the Political Dimension of Contemporary Art

ERIC Educational Resources Information Center

Peters, Clorinde

2015-01-01

In a neoliberal moment of cultural production marked by commodification and the dominance of economic values, it is necessary to investigate the cultural, social, and aesthetic value of art. By examining Herbert Marcuse's aesthetic dimension, this article seeks to locate the political and pedagogic potential both in the aesthetics and in the…

Evaluating Teaching in Higher Education. A Collection of Conference Papers.

ERIC Educational Resources Information Center

London Univ. (England). Inst. of Education.

Some of the difficult problems related to introducing greater accountability for teaching were assessed and tentative policies considered at a British conference on higher education held in April 1975. R.C. Tress, Peter Kennedy, R. Rickett, Tom Driver, Marcus Merriman, and Alastair Stewart are the authors of the first set of papers entitled…

Molecular Dynamics Simulations of the Hydrogen Peroxyl Radical

DTIC Science & Technology

2014-05-01

Pasta , and Ulam10 (FPU) on the equipartion of energy in a one-dimensional anharmonic chain of oscillators yielded results that surprised the...Slater, Proc. Camb. Phil. Soc. 35, 56 (1939). 9 R. A. Marcus, J. Chem. Phys. 20, 359 (1952). 10 E. Fermi, J. R. Pasta , and S. M. Ulam, Los Alamos

The Voice of Authority

ERIC Educational Resources Information Center

Wetterlund, Kris

2012-01-01

In the last part of 2011, conversations swirled around the Internet and print about the assault on museum authority. The Marcus Institute for Digital Education in the Arts (MIDEA) summarized some of the discussion in their blog entry "The Participatory Museum and a New Authority." Other sites joined in the discussion, for example, the Museum Geek…

20 CFR Appendix A to Subpart F of... - U.S. Seaports

Code of Federal Regulations, 2010 CFR

2010-04-01

... Port, LA New Orleans, LA Beaumont, TX Brownsville, TX Corpus Christi, TX Freeport, TX Galveston, TX..., MA Fall River, MA New Bedford, MA Providence, RI Bridgeport, CT New Haven, CT New London, CT Albany, NY New York, NY/NJ Camden, NJ Gloucester City, NJ Paulsboro, NJ Chester, PA Marcus Hook, PA...

Factors Associated with Transitional Shifts in College Students' Physical Activity Behavior

ERIC Educational Resources Information Center

Levy, Susan S.; Cardinal, Bradley J.

2006-01-01

The Transtheoretical Model (Prochaska & Marcus, 1994) has been widely used as a framework for understanding exercise behavior change. The purpose of this study was to clarify equivocal research findings reported for model predictions when examining stage movement over time rather than static stages and to provide some evidence of the construct…

National CrossTalk. Volume 14, Number 3, Summer 2006

ERIC Educational Resources Information Center

Trombley, William, Ed.

2006-01-01

The primary purpose of "National CrossTalk" is to stimulate informed discussion and debate of higher education issues. This issue contains the following articles: (1) The M Word: "Marketing" Has Changed from a Dirty Word to a Buzzword in Higher Education (Jon Marcus); (2) A Contrarian View of the Testing Industry: FairTest…

Return on Investment in the Public Sector

DTIC Science & Technology

2004-12-01

of Corporate Finance . 4th Ed. New York: McGraw-Hill/Irwin, 2004. Brook, Douglas A. <dabrook@nps.navy.mil> “CNO Visit.” [E-mail to Larry Jones...Analysis: Concepts and Practice. 10th Ed. Upper Saddle River: Prentice Hall, 1996. Brealey, Richard, Alan J. Marcus, and Stewart C. Myers. Fundamentals

Neoteny, Dialogic Education and an Emergent Psychoculture: Notes on Theory and Practice

ERIC Educational Resources Information Center

Kennedy, David

2014-01-01

This article argues that children represent one vanguard of an emergent shift in Western subjectivity, and that adult-child dialogue, especially in the context of schooling, is a key locus for the epistemological change that implies. Following Herbert Marcuse's invocation of a "new sensibility", the author argues that the…

Relative importance of driving force and electrostatic interactions in the reduction of multihaem cytochromes by small molecules.

PubMed

Quintas, Pedro O; Cepeda, Andreia P; Borges, Nuno; Catarino, Teresa; Turner, David L

2013-06-01

Multihaem cytochromes are essential to the energetics of organisms capable of bioremediation and energy production. The haems in several of these cytochromes have been discriminated thermodynamically and their individual rates of reduction by small electron donors were characterized. The kinetic characterization of individual haems used the Marcus theory of electron transfer and assumed that the rates of reduction of each haem by sodium dithionite depend only on the driving force, while electrostatic interactions were neglected. To determine the relative importance of these factors in controlling the rates, we studied the effect of ionic strength on the redox potential and the rate of reduction by dithionite of native Methylophilus methylotrophus cytochrome c″ and three mutants at different pH values. We found that the main factor determining the rate is the driving force and that Marcus theory describes this satisfactorily. This validates the method of the simultaneous fitting of kinetic and thermodynamic data in multihaem cytochromes and opens the way for further investigation into the mechanisms of these proteins. Copyright © 2013 Elsevier B.V. All rights reserved.

Charge transfer in model peptides: obtaining Marcus parameters from molecular simulation.

PubMed

Heck, Alexander; Woiczikowski, P Benjamin; Kubař, Tomáš; Giese, Bernd; Elstner, Marcus; Steinbrecher, Thomas B

2012-02-23

Charge transfer within and between biomolecules remains a highly active field of biophysics. Due to the complexities of real systems, model compounds are a useful alternative to study the mechanistic fundamentals of charge transfer. In recent years, such model experiments have been underpinned by molecular simulation methods as well. In this work, we study electron hole transfer in helical model peptides by means of molecular dynamics simulations. A theoretical framework to extract Marcus parameters of charge transfer from simulations is presented. We find that the peptides form stable helical structures with sequence dependent small deviations from ideal PPII helices. We identify direct exposure of charged side chains to solvent as a cause of high reorganization energies, significantly larger than typical for electron transfer in proteins. This, together with small direct couplings, makes long-range superexchange electron transport in this system very slow. In good agreement with experiment, direct transfer between the terminal amino acid side chains can be dicounted in favor of a two-step hopping process if appropriate bridging groups exist. © 2012 American Chemical Society

Germ-line PHD1 and PHD2 mutations detected in patients with pheochromocytoma/paraganglioma-polycythemia.

PubMed

Yang, Chunzhang; Zhuang, Zhengping; Fliedner, Stephanie M J; Shankavaram, Uma; Sun, Michael G; Bullova, Petra; Zhu, Roland; Elkahloun, Abdel G; Kourlas, Peter J; Merino, Maria; Kebebew, Electron; Pacak, Karel

2015-01-01

We have investigated genetic/pathogenetic factors associated with a new clinical entity in patients presenting with pheochromocytoma/paraganglioma (PHEO/PGL) and polycythemia. Two patients without hypoxia-inducible factor 2α (HIF2A) mutations, who presented with similar clinical manifestations, were analyzed for other gene mutations, including prolyl hydroxylase (PHD) mutations. We have found for the first time a germ-line mutation in PHD1 in one patient and a novel germ-line PHD2 mutation in a second patient. Both mutants exhibited reduced protein stability with substantial quantitative protein loss and thus compromised catalytic activities. Due to the unique association of patients' polycythemia with borderline or mildly elevated erythropoietin (EPO) levels, we also performed an in vitro sensitivity assay of erythroid progenitors to EPO and for EPO receptor (EPOR) expression. The results show inappropriate hypersensitivity of erythroid progenitors to EPO in these patients, indicating increased EPOR expression/activity. In addition, the present study indicates that HIF dysregulation due to PHD mutations plays an important role in the pathogenesis of these tumors and associated polycythemia. The PHD1 mutation appears to be a new member contributing to the genetic landscape of this novel clinical entity. Our results support the existence of a specific PHD1- and PHD2-associated PHEO/PGL-polycythemia disorder. • A novel germ-l i n e PHD1 mutation causing heochromocytoma/paraganglioma and polycythemia. • Increased EPOR activity and inappropriate hypersensitivity of erythroid progenitors to EPO.

Pre-hospital discharge testing of defibrillator without anesthesia: effects on psychological symptoms during clinical follow-up.

PubMed

Petrowski, Katja; Wintermann, Gloria-Beatrice; Petzold, Christian; Strasser, Ruth H; Guenther, Michael

2013-09-01

After the implantation of an implantable cardioverter-defibrillator (ICD), patients often fear therapeutic shock. The extent to which the experience of pre-hospital discharge (PHD) testing without anesthesia after ICD implantation, under observation by a physician, affects shock-related anxiety symptoms on follow-up has not been investigated as yet. In a prospective, randomized controlled trial, 44 patients with a primary prevention indication for an ICD were randomly assigned to experience PHD testing without anesthesia (n = 23) or with anesthesia (n = 21). Patients were longitudinally evaluated before (T(1)), shortly after (T(2)), and 3 months after (T(3)) PHD testing. During the respective PHD testings, the course of patients' serum cortisol release was measured. During PHD testing, patients without anesthesia showed a significantly higher serum cortisol release than patients with anesthesia (F(4,152) = 22.227, p < .001). Patients who experienced PHD testing without anesthesia felt significantly safer with the ICD (U = 165.000, p = .040), would significantly more often recommend other patients to undergo PHD testing without anesthesia (χ(2) = 12.013, p = .002), and showed significantly lower levels of general shock-related anxiety shortly afterward (F(1,42) = 6.327, p = .02) and 3 months after PHD testing (F(1,41) = 8.603, p = .005). The implementation of PHD testing without anesthesia is associated with lower anxiety concerning therapeutic shock. Patients should be advised about the effects of PHD testing without anesthesia on their psychological well-being in the long run.

I-determinants for a successful PhD or postdoctoral outcome.

PubMed

Sørensen, Henrik Toft

2016-01-01

Many resources are invested in research training, but very little literature exists on predictors for a successful PhD and postdoctoral training outcome. A PhD program has two overall objectives: to extend knowledge about a hopefully important health topic and to provide extensive training to improve the PhD student's skills through learning research methods and collaboration. A substantial number of PhD students may run into some kind of problem in the course of their PhD program. In this article, some determinants all starting with an "I" and indicative of a good PhD outcome are reported. The successful PhD student can be described as having an Interest in the PhD program, an Incentive for the program, and an Idea of what he or she wants to investigate, showing Initiative, and having high personal Integrity and good Interpersonal relationships. When these so-called I-determinants are present, the likelihood of success in a PhD program is high. More evidence is available for selection of candidates for postdoctoral appointments since it is known that the postdoctoral candidate has completed a PhD program, published papers in peer-reviewed journals, and received awarded grants. However, other characteristics determine a successful transition of the postdoctoral candidate into a research leader. These determinants are Identity, Independence and Image, Implementation ability in terms of being able to implement decisions and projects, working with Innovative and Important topics, having In-depth knowledge of the research topic, being Interactive and Integrated with the scientific community, and Internationally oriented. In conclusion, regardless of the framework of research, the personal characteristics of a researcher play a very important role in the quality of research. Application of some of the principles mentioned in this article might allow decision to reach a more evidence-based way to recruit PhD students and postdoctorals.

I-determinants for a successful PhD or postdoctoral outcome

PubMed Central

Sørensen, Henrik Toft

2016-01-01

Many resources are invested in research training, but very little literature exists on predictors for a successful PhD and postdoctoral training outcome. A PhD program has two overall objectives: to extend knowledge about a hopefully important health topic and to provide extensive training to improve the PhD student’s skills through learning research methods and collaboration. A substantial number of PhD students may run into some kind of problem in the course of their PhD program. In this article, some determinants all starting with an “I” and indicative of a good PhD outcome are reported. The successful PhD student can be described as having an Interest in the PhD program, an Incentive for the program, and an Idea of what he or she wants to investigate, showing Initiative, and having high personal Integrity and good Interpersonal relationships. When these so-called I-determinants are present, the likelihood of success in a PhD program is high. More evidence is available for selection of candidates for postdoctoral appointments since it is known that the postdoctoral candidate has completed a PhD program, published papers in peer-reviewed journals, and received awarded grants. However, other characteristics determine a successful transition of the postdoctoral candidate into a research leader. These determinants are Identity, Independence and Image, Implementation ability in terms of being able to implement decisions and projects, working with Innovative and Important topics, having In-depth knowledge of the research topic, being Interactive and Integrated with the scientific community, and Internationally oriented. In conclusion, regardless of the framework of research, the personal characteristics of a researcher play a very important role in the quality of research. Application of some of the principles mentioned in this article might allow decision to reach a more evidence-based way to recruit PhD students and postdoctorals. PMID:27574466

Online PhD Program Delivery Models and Their Relationship to Student Success

ERIC Educational Resources Information Center

Jorissen, Shari L.

2012-01-01

Attrition rates in Ph.D. programs are at approximately 50% in traditional Ph.D. programs and 10-20% higher in online Ph.D. programs. Understanding the relationship between student factors, measures of student success (retention, graduation, year to degree), and student satisfaction is important to support and improve retention, graduation rates,…

Undertaking Individual Transdisciplinary PhD Research for Sustainable Development: Case Studies from South Africa

ERIC Educational Resources Information Center

van Breda, John; Musango, Josephine; Brent, Alan

2016-01-01

Purpose: This paper aims to improve the understanding of individual transdisciplinary PhD research in a developing country context, focusing on three individual PhD case studies in South Africa. Design/Methodology/Approach: Multiple-case method was used, and three completed transdisciplinary PhD research efforts undertaken at the Stellenbosch…

PhD Funding as a Determinant of PhD and Career Research Performance

ERIC Educational Resources Information Center

Horta, Hugo; Cattaneo, Mattia; Meoli, Michele

2018-01-01

This article focuses on the effects of PhD funding on research performance both during the degree and throughout researchers' careers as measured through publications and citations. This analysis draws from a representative sample of researchers holding a doctorate based in Portugal and finds that those funded by grants during the PhD perform…

International PhD Students in Australian Universities: Financial Support, Course Experience and Career Plans

ERIC Educational Resources Information Center

Harman, G.

2003-01-01

Using data from a social survey of PhD students in two major Australian universities supplemented by student interviews, this article reports on the financial support, course experience and career plans of international PhD students. While most international PhD students hold scholarships which include stipends, a minority of students experience…

A Reconsideration of the Ph.D.

ERIC Educational Resources Information Center

Nichols, Roy F.

1967-01-01

One of the major problems in doctoral education, the shortage of Ph.D. holders, is discussed. A brief history of the German influence on graduate schools in the United States is given to suggest the reasons why the traditional Ph.D. is not designed for present needs. Suggestions are given for a more effective Ph.D. curriculum which will meet the…

High Power, Millimeter-Wavelength, Coherent Radiation Sources.

DTIC Science & Technology

1986-09-25

J . Murphy, Ph.D. (1982). 5. M. Abdelkarim , Ph.D. (1984). 6. T. Buller, Ph.D. (1985). a 7. B. Johnson, Ph.D. (1985). 8. E. Garate, Ph.D. (1985). 9. R...AD-A174 521 HIGH POWER KILL IMETER-WAVELENGTH COHERENTRAITO 1/ SOURCES(U) DARTMOUTH COLL HANOVER N H DEPT OF PHYSICS AND ASTRONOMY J E WALSH 25 SEP...82 - 1/31/86 -.: AIR F , 2 ..... . . T . ... ...... , 7 Approved for public release;"":" " ’n2. j ;’L’-’ ,- -"!d ,-d 12 l . 7. ... - ’ " + d. Chief

DOE Office of Scientific and Technical Information (OSTI.GOV)

Howell, Matthew D.; McLellan, Jason G.

This report summarizes catch data collected from white sturgeon Acipenser transmontanus in Lake Roosevelt during limited setlining and gill netting activities in the fall of 2003, and documents progress toward development of a U.S. white sturgeon conservation aquaculture program for Lake Roosevelt. From 27-30 October, 42 overnight small mesh gill net sets were made between Marcus and Northport, WA for a total catch of 15 juvenile white sturgeon (275-488 mm FL). All sturgeon captured were of Canadian hatchery origin. These fish had been previously released as sub-yearlings into the Canadian portion (Keenleyside Reach) of the Transboundary Reach of the Columbiamore » River during 2002 and 2003. Most sturgeon (n=14) were caught in the most upstream area sampled (Northport) in low velocity eddy areas. Five fish exhibited pectoral fin deformities (curled or stunted). Growth rates were less than for juvenile sturgeon captured in the Keenleyside Reach but condition factor was similar. Condition factor was also similar to that observed in juvenile sturgeon (ages 1-8) captured in the unimpounded Columbia River below Bonneville Dam between 1987-92. From 10-14 November, 28 overnight setline sets were made in the Roosevelt Reach between the confluence of the Spokane River and Marcus Island for a total catch of 17 white sturgeon (94-213 cm FL). Catch was greatest in the most upstream areas sampled, a distribution similar to that observed during a WDFW setline survey in Lake Roosevelt in 1998. The mean W{sub r} index of 110% for fish captured this year was higher than the mean W{sub r} of 91% for fish captured in 1998. Excellent fish condition hindered surgical examination of gonads as lipid deposits made the ventral body wall very thick and difficult to penetrate with available otoscope specula. Acoustic tags (Vemco model V16 coded pingers, 69 kHz, 48-month life expectancy) were internally applied to 15 fish for subsequent telemetry investigations of seasonal and reproductively motivated movements. In August 2003, three Vemco VR2 fixed station acoustic receivers, supplied by the UCWSRI Transboundary Telemetry Project, were deployed in the vicinities of Kettle Falls Bridge, Marcus Island, and Northport, WA. Data downloaded from these receivers through December 2003 confirmed the findings of a previous telemetry study that the Marcus area is an important overwintering habitat for white sturgeon. On 18 February 2004, juvenile white sturgeon (n=2,000) were transported from Kootenay Sturgeon Hatchery in British Columbia to WDFW Columbia Basin Hatchery (CBH) in Moses Lake, WA. Fish were reared at CBH to approximately 30 g and individually outfitted with PIT tags and scute marked. On 11 May 2004, fish were released into Lake Roosevelt in the vicinities of Kettle Falls Bridge, North Gorge, and Northport.« less

STS-89 M.S. Sharipov of the RSA arrives at the SLF

NASA Technical Reports Server (NTRS)

1998-01-01

STS-89 Mission Specialist Salizhan Sharipov of the Russian Space Agency arrives at the KSC Shuttle Landing Facility in one of the T-38 aircraft traditionally flown by the astronaut corps. The eight STS-89 crew members flew into KSC from Johnson Space Center as final preparations are under way toward the scheduled liftoff on Jan. 22 of the Space Shuttle Endeavour on the eighth mission to dock with the Russian Space Station Mir. After docking, STS-89 Mission Specialist Andrew Thomas, Ph.D., will transfer to the space station, succeeding David Wolf, M.D., who will return to Earth aboard Endeavour. Dr. Thomas will live and work on Mir until June. STS-89 is scheduled for a Jan. 22 liftoff at 9:48 p.m. EST.

STS-90 M.S. Pawelczyk stands behind his children near Pad 39B

NASA Technical Reports Server (NTRS)

1998-01-01

STS-90 Payload Specialist James Pawelczyk, Ph.D., stands behind his two children, Bradley and Katlyn (left to right), as they smile to photographers near Launch Pad 39B. James and the rest of the seven-member crew are scheduled to launch aboard Columbia, seen in the background, on May 16 at 2:19 p.m. EDT. The astronauts are under strict health stabilization guidelines to protect them from close contact with persons who do not have health stabilization clearance. This is the 25th flight of Columbia and the 90th mission flown since the start of the Space Shuttle program. This launch of Neurolab will examine the effects of spaceflight on the brain, spinal cord, peripheral nerves and sensory organs in the human body.

Acceptance of a systematic review as a thesis: survey of biomedical doctoral programs in Europe.

PubMed

Puljak, Livia; Sapunar, Damir

2017-12-12

Systematic reviews (SRs) have been proposed as a type of research methodology that should be acceptable for a graduate research thesis. The aim of this study was to analyse whether PhD theses in European biomedical graduate programs can be partly or entirely based on SRs. In 2016, we surveyed individuals in charge of European PhD programs from 105 institutions. The survey asked about acceptance of SRs as the partial or entire basis for a PhD thesis, their attitude towards such a model for PhD theses, and their knowledge about SR methodology. We received responses from 86 individuals running PhD programs in 68 institutions (institutional response rate of 65%). In 47% of the programs, SRs were an acceptable study design for a PhD thesis. However, only 20% of participants expressed a personal opinion that SRs meet the criteria for a PhD thesis. The most common reasons for not accepting SRs as the basis for PhD theses were that SRs are 'not a result of a PhD candidate's independent work, but more of a team effort' and that SRs 'do not produce enough new knowledge for a dissertation'. The majority of participants were not familiar with basic concepts related to SRs; questions about meta-analyses and the type of plots frequently used in SRs were correctly answered by only one third of the participants. Raising awareness about the importance of SRs and their methodology could contribute to higher acceptance of SRs as a type of research that forms the basis of a PhD thesis.

Driver performance and behavior in adverse weather conditions : an investigation using the SHRP2 naturalistic driving study data--phase 1.

DOT National Transportation Integrated Search

2015-12-01

Mohamed M. Ahmed, Ph.D., P.E. (orcid.org/0000-0002-1921-0724) : Ali Ghasemzadeh, M.Sc. (orcid.org/0000-0003-1232-251X) : Hesham Eldeeb, Ph.D. : Sherif Gaweesh, M.Sc. (orcid.org/0000-0001-7977-6378) : Joshua Clapp, Ph.D. : Khaled Ksaibati, Ph.D., P.E....

How Prepared Are MSW Graduates for Doctoral Research? Views of PhD Research Faculty

ERIC Educational Resources Information Center

Drisko, James W.; Evans, Kristin

2018-01-01

This national survey of PhD faculty assessed the research preparation of entering doctoral social work students on a wide range of research knowledge and related skills. The prior literature shows that PhD programs repeat much BSW and MSW research course content. This study shows that the trend continues and has perhaps widened. PhD research…

Academic and research misconduct in the PhD: issues for students and supervisors.

PubMed

Mitchell, Theresa; Carroll, Jude

2008-02-01

There are many pressures upon PhD students not least the requirement to make an original or significant contribution to knowledge. Some students, confronted with complex research processes, might adopt practices that compromise standards that are unacceptable within a research community. These practices challenge the PhD student-supervisor relationship and have implication for the individual, the supervisory team, the institution, the awarding body and the wider research context. Discussion relating to misconduct within the PhD is of international importance if the aim is to encourage and facilitate rigorous research practice. Cases involving academic and research misconduct, especially those occurring at PhD level, are likely to become more frequent as numbers of PhD students increase and will demand appropriate, defensible responses from supervisors. Misconduct during PhD study can be difficult to resolve because of lack of clarity in definitions, supervisor naiveté and failure to acknowledge students' decision making limitations. Using scenarios from the first author's supervisory practice to illustrate issues of concern for students and supervisors during PhD supervision, the authors aim to illuminate the importance of engagement with regulatory bodies; problems of knowledge and understanding transfer; culturally specific issues and meanings of academic theft.

Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization

PubMed Central

Loges, Sonja; Schmidt, Thomas; Jonckx, Bart; Tian, Ya-Min; Lanahan, Anthony A.; Pollard, Patrick; de Almodovar, Carmen Ruiz; De Smet, Frederik; Vinckier, Stefan; Aragonés, Julián; Debackere, Koen; Luttun, Aernout; Wyns, Sabine; Jordan, Benedicte; Pisacane, Alberto; Gallez, Bernard; Lampugnani, Maria Grazia; Dejana, Elisabetta; Simons, Michael; Ratcliffe, Peter; Maxwell, Patrick; Carmeliet, Peter

2014-01-01

SUMMARY A key function of blood vessels, to supply oxygen, is impaired in tumors because of abnormalities in their endothelial lining. PHD proteins serve as oxygen sensors and may regulate oxygen delivery. We therefore studied the role of endothelial PHD2 in vessel shaping by implanting tumors in PHD2+/− mice. Haplodeficiency of PHD2 did not affect tumor vessel density or lumen size, but normalized the endothelial lining and vessel maturation. This resulted in improved tumor perfusion and oxygenation and inhibited tumor cell invasion, intravasation, and metastasis. Haplodeficiency of PHD2 redirected the specification of endothelial tip cells to a more quiescent cell type, lacking filopodia and arrayed in a phalanx formation. This transition relied on HIF-driven upregulation of (soluble) VEGFR-1 and VE-cadherin. Thus, decreased activity of an oxygen sensor in hypoxic conditions prompts endothelial cells to readjust their shape and phenotype to restore oxygen supply. Inhibition of PHD2 may offer alternative therapeutic opportunities for anticancer therapy. PMID:19217150

ERα upregulates Phd3 to ameliorate HIF-1 induced fibrosis and inflammation in adipose tissue

PubMed Central

Kim, Min; Neinast, Michael D.; Frank, Aaron P.; Sun, Kai; Park, Jiyoung; Zehr, Jordan A.; Vishvanath, Lavanya; Morselli, Eugenia; Amelotte, Mason; Palmer, Biff F.; Gupta, Rana K.; Scherer, Philipp E.; Clegg, Deborah J.

2014-01-01

Hypoxia Inducible Factor 1 (HIF-1) promotes fibrosis and inflammation in adipose tissues, while estrogens and Estrogen Receptor α (ERα) have the opposite effect. Here we identify an Estrogen Response Element (ERE) in the promoter of Phd3, which is a negative regulatory enzyme of HIF-1, and we demonstrate HIF-1α is ubiquitinated following 17-β estradiol (E2)/ERα mediated Phd3 transcription. Manipulating ERα in vivo increases Phd3 transcription and reduces HIF-1 activity, while addition of PHD3 ameliorates adipose tissue fibrosis and inflammation. Our findings outline a novel regulatory relationship between E2/ERα, PHD3 and HIF-1 in adipose tissues, providing a mechanistic explanation for the protective effect of E2/ERα in adipose tissue. PMID:25161887

Award for Distinguished Contributions to the International Advancement of Psychology.

PubMed

2017-12-01

This award is given to individuals who have made sustained and enduring contributions to international cooperation and the advancement of knowledge in psychology. The 2017 recipient of the APA Award for Distinguished Contributions to the International Advancement of Psychology was selected by the 2016 Committee on International Relations in Psychology (CIRP). The members of the 2016 CIRP were Melissa Morgan Consoli, PhD, and Arpana G. Inman, PhD (Co-chairs); Rehman Abdulrehman, PhD; Gonzalo Bacigalupe, EdD; Frederic Bemak, EdD; Brigitte Khoury, PhD; Susan Nolan, PhD; Nancy Sidun, PsyD; and Danny Wedding, PhD. Dr. Morgan Consoli, Dr. Inman, Dr. Nolan, and Doctor Sidun were members of the subcommittee for the 2017 award. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Using a nursing theory or a model in nursing PhD dissertations: a qualitative study from Turkey.

PubMed

Mete, Samiye; Gokçe İsbir, Gozde

2015-04-01

The aim of this study was to reveal experiences of nursing students and their advisors using theories and models in their PhD dissertations. The study adopted a descriptive qualitative approach. This study was performed with 10 PhD candidates and their five advisors from nursing faculty. The results of the study were categorized into four. These are reasons for using a theory/model in a PhD dissertation, reasons for preferring a given model, causes of difficulties in using models in PhD dissertations, and facilitating factors of using theories and models in PhD of dissertations. It was also reported to contribute to the methodology of research and professional development of the students and advisors. © 2014 NANDA International, Inc.

Developing Discourses of Knowledge and Understanding: Longitudinal Studies of Ph.D. Supervision

ERIC Educational Resources Information Center

Kandiko, Camille B.; Kinchin, Ian M.

2013-01-01

Competing notions of what a Ph.D. has been, is and should be are undercurrents in doctoral education. A longitudinal study of Ph.D. supervision based on interviews and concept mapping was used to surface understandings of the purpose of a Ph.D. This research tracks change over time for both the student and the supervisor. The data were analysed…

Factors Contributing to High PhD Completion Rates: A Case Study in a Research-Intensive University in New Zealand

ERIC Educational Resources Information Center

Spronken-Smith, Rachel; Cameron, Claire; Quigg, Robin

2018-01-01

This exploratory study determined PhD completions at a research-intensive university in New Zealand and considered factors affecting PhD completions. Completion data were calculated for PhD cohorts at the University of Otago from 2000 to 2012 (n = 2770) and survival models determined whether gender, enrolment status, age at admission, citizenship,…

Trust Me, I'm a Doctor: A PhD Survival Guide

ERIC Educational Resources Information Center

Deconinck, Koen

2015-01-01

So, you have decided to do a PhD … now what? In this essay, the author provides some advice for beginning PhD students, basically sharing what he would tell his younger self. Doing a PhD is a transformative experience, but the process is challenging, not merely on an intellectual level but also psychologically. To overcome these challenges, one…

A National Content Analysis of PhD Program Objectives, Structures, and Curricula: Do Programs Address the Full Range of Social Work's Needs?

ERIC Educational Resources Information Center

Drisko, James; Hunnicutt, Christie; Berenson, Laura

2015-01-01

The Group for the Advancement of Doctoral Education (GADE) promotes excellence in PhD education in Social Work. GADE's 2013 Quality Guidelines for PhD Programs heavily emphasize preparation for research. Little is known, however, about the details of the contemporary social work PhD program structure and curriculum. Several prior surveys have…

The Purpose of the PhD: Theorising the Skills Acquired by Students

ERIC Educational Resources Information Center

Mowbray, Susan; Halse, Christine

2010-01-01

In the past decade there has been a marked push for the development of employability skills to be part of the PhD process. This push is generally by stakeholders from above and outside the PhD process, i.e. government and industry, who view skills as a "summative product" of the PhD. In contrast, our study interviewed stakeholders inside…

Cherry Featured in NCI’s Spotlight on Scientists Video Series | Poster

Cancer.gov

James Cherry, Ph.D., learned at an early age that education is crucial to success. He credits his mentors, some of whom include his grandmother, Shepherd University professor Burton Lidgerding, Ph.D., David Munroe, Ph.D., Frederick National Lab, and Robert J. Hohman, Ph.D., National Institute of Allergy and Infectious Diseases, for guiding him to the career he has today.

Clinical Investigation Program Annual Progress Report

DTIC Science & Technology

1989-10-01

Investigators: Linda K. Kullama, Ph.D., Dr. Kenneth T. Nakamura,MD; Dr. Venkataraman Balaraman, MD, Wayne M. Ichimura, Biomedical Engineer. Department/Section...Investigators: John R. Claybaugh, Ph.D.; Kenneth T. Nakamura, MD; Dr. Venkataraman Balaraman, M.D. Department/Section: Clinical Investigation/Physiology Key...Pigs and Rats Principal ’Investigator: Linda K. Kullama, Ph.D.; John R. Claybaugh, Ph.D. Associate Investigators: Dr. Venkataraman Balaraman, M.D.; Dr

Characterization of Bc1-2, Bc1-xL, and Bax Pore Formation and Their Role in Apoptosis Regulation

DTIC Science & Technology

2002-01-01

Bcl-2, Bcl-xL, and Bax Pore Formation and Their Role in Apoptosis Regulation PRINCIPAL INVESTIGATOR: Frank Stenner -Liewen, Ph.D. Sharon Schendel, Ph.D...AUTHOR(S) Frank Stenner -Liewen, Ph.D. Sharon Schendel, Ph.D. John C. Reed, M.D., Ph.D. 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING

Optimal Autonomous Spacecraft Resiliency Maneuvers Using Metaheuristics

DTIC Science & Technology

2014-09-15

Optimization of Interplanetary Trajectories,” Journal of Spacecraft and Rockets, Vol. 46, No. 2, March-April 2009, pp. 365–372. [23] Subbarao , K . and...Black, PhD (Chairman) /signed/ Darryl K . Ahner, PhD (Member) /signed/ Raymond R. Hill, PhD (Member) /signed/ William E. Wiesel, PhD (Member) 29 Jul 2014...124 Appendix A: Derivation of Spherical Equations of Motion . . . . . . . . . . . . . . 126 Appendix B : Equations of

EXPERIMENTAL INDUCTION OF CHRONIC PULMONARY DISEASE IN GENETICALLY SUSCEPTIBLE RAT MODEL

EPA Science Inventory

Experimental induction of chronic pulmonary disease in genetically susceptible rat model. M.C.Schladweiler, BS 1, A.D.Ledbetter 1, K.E.Pinkerton, PhD 2, K.R.Smith, PhD 2, P.S.Gilmour, PhD 1, P.A.Evansky 1, D.L.Costa, ScD 1, W.P.Watkinson, PhD 1, J.P.Nolan 1 and U.P.Kodava...

Modelling Research: A Collaborative Approach to Helping PhD Students Develop Higher-Level Research Skills

ERIC Educational Resources Information Center

Garcia-Perez, Alexeis; Ayres, Robert

2012-01-01

A high proportion of PhD candidates in science and engineering fail to complete their degrees. This paper reports the results of a series of workshops where experienced researchers and supervisors were brought together with PhD students to discuss and develop a model of the PhD process. The objective was to help students develop a more rounded and…

Electronic communication across diamagnetic metal bridges: a homoleptic gallium(III) complex of a redox-active diarylamido-based ligand and its oxidized derivatives

PubMed Central

Liddle, Brendan J.; Wanniarachchi, Sarath; Hewage, Jeewantha S.; Lindeman, Sergey V.; Bennett, Brian; Gardinier, James R.

2012-01-01

Complexes with cations of the type [Ga(L)2]n+ where L = bis(4-methyl-2-(1H-pyrazol-1-yl)phenyl)amido and n = 1, 2, 3 have been prepared and structurally characterized. The electronic properties of each were probed by electrochemical and spectroscopic means and were interpreted with the aid of DFT calculations. The dication, best described as [Ga(L−)(L0)]2+, and is a Robin-Day class II mixed-valence species. As such, a broad, weak, solvent-dependent intervalence charge transfer (IVCT) band was found in the NIR spectrum in the range 6390 to 6925 cm−1, depending on solvent. Band shape analyses and the use of Hush and Marcus relations revealed a modest electronic coupling, Hab of about 200 cm−1, and a large rate constant for electron transfer, ket, on the order of 1010 s−1 between redox active ligands. The di-oxidized complex [Ga(L0)2]3+ shows a half-field ΔMs = 2 transition in its solid-state X-Band EPR spectrum at 5 K which indicates that the triplet state is thermally populated. DFT calculations (M06/Def2-SV(P)) suggest that the singlet state is 21.7 cm−1 lower in energy than the triplet state. PMID:23163736

Methods for Scaling to Doubly Stochastic Form,

DTIC Science & Technology

1981-06-26

Frobenius -Konig Theorem (MARCUS and MINC [1964],p 97) A nonnegative n xn matrix without support contains an s x t zero subma- trix where: s +t =n + -3...that YA(k) has row sums 1. Then normalize the columns by a diagonal similarity transform defined as follows: Let x = (zx , • z,,) be a left Perron vector

Fostering Persistence: 3D Printing and the Unforeseen Impact on Equity

ERIC Educational Resources Information Center

FitzPatrick, Daniel L.; Dominguez, Victoria S.

2017-01-01

Teaching persistence and problem solving must begin with selecting a problem that can be solved mathematically, that allows for multiple methods of solving, and that generally captures the attention and curiosity of the student (Marcus and Fey 2003; NCTM 1991; Van de Walle 2003). This article shows how a STEM three-dimensional (3D) printing…

Herbert Marcuse's Theory of Play--A Social Philosophical Perspective.

ERIC Educational Resources Information Center

Volkwien, Karin A. E.

Sport has been widely discussed, by conservatives who argue that sport operates within the realm of freedom, and so lies outside the deterministic nexus of capitalist economics and policies, and leftists who argue that sport reproduces the repressive features of capitalism and serves as an ideological tool of the latter. The purpose of this study…

Joint Services Electronics Program (Harvard University. Cambridge, Massachusetts)

DTIC Science & Technology

1988-09-30

34Band Structures of Semimagnetic Compounds," Acta Physica Polonica bf A73 (6), 933-941 (1988). (Partially supported by N00014-86-K-0760). c. Books...Journals K.L. Babcock and R.M. Westervelt, "Dynamics of Simple Electronic neural Net- works," Physica 28D, 305 (1987). C.M. Marcus and R.M. Westervelt

Naive Probability: Model-based Estimates of Unique Events

DTIC Science & Technology

2014-05-04

Gilio & Over, 2012) – a possibility to which we return later. Despite these studies...Barrouillet, Jean-François Bonnefon, Nick Cassimatis, Nick Chater, Ernest Davis, Igor Douven, Angelo Gilio , Adam Harris, Gernot Kleiter, Gary Marcus, Ray...1230-1239. Gilio , A., & Over, D. (2012). The psychology of inferring conditionals from disjunctions: A probabilistic study. Journal of

The Rapid Detection of Single Bacterial Cells by Deep UV Micro Raman Spectroscopy.

DTIC Science & Technology

1992-04-01

Saltzman and C.T. Gregg, Appl. Environ. Microbiol. 44, 1081 (1982). 14. D.’. Mc Greggor, W.K. Grace and G.C. Salzman, in "Rapid Methods and...was used by Dr. Marcus Peter of the Dana -Farber Cancer Institute. During that period he came to our laboratories weekly to study GTP- binding

"Spreading the Love" and Using Performances to Prevent Rape

ERIC Educational Resources Information Center

Murphy, Aurora

2013-01-01

While rape is ordinarily considered an invariable reality, Sharon Marcus argues that it is instead a cultural script, which casts women as victims and men as perpetrators. In imagining rape as a script, it may seem pertinent to suggest that the arts and performance have a role in its prevention. Performances can provide a forum to publicly reflect…

76 FR 26255 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-06

..., the R/V Marcus G. Langseth (Langseth) and a seismic airgun array to collect seismic reflection and... possible, depending on logistics and weather. The proposed seismic survey will collect seismic reflection... Shillington, Spahr Webb, and Mladen Nedimovic, all of L-DEO. The vessel will be self-contained, and the crew...

The Oxidation of Ascorbic Acid by Hexacyanoferrate(III) Ion in Acidic Aqueous Media.

ERIC Educational Resources Information Center

Martins, Luis J. A.; da Costa, J. Barbosa

1988-01-01

Describes a kinetic and mechanistic investigation of ascorbic acid by a substitution-inert complex in acidic medium suitable for the undergraduate level. Discusses obtaining the second order rate constant for the rate determining step at a given temperature and comparison with the value predicted on the basis of the Marcus cross-relation. (CW)

Exploring PHD fingers and H3K4me0 interactions with molecular dynamics simulations and binding free energy calculations: AIRE-PHD1, a comparative study.

PubMed

Spiliotopoulos, Dimitrios; Spitaleri, Andrea; Musco, Giovanna

2012-01-01

PHD fingers represent one of the largest families of epigenetic readers capable of decoding post-translationally modified or unmodified histone H3 tails. Because of their direct involvement in human pathologies they are increasingly considered as a potential therapeutic target. Several PHD/histone-peptide structures have been determined, however relatively little information is available on their dynamics. Studies aiming to characterize the dynamic and energetic determinants driving histone peptide recognition by epigenetic readers would strongly benefit from computational studies. Herein we focus on the dynamic and energetic characterization of the PHD finger subclass specialized in the recognition of histone H3 peptides unmodified in position K4 (H3K4me0). As a case study we focused on the first PHD finger of autoimmune regulator protein (AIRE-PHD1) in complex with H3K4me0. PCA analysis of the covariance matrix of free AIRE-PHD1 highlights the presence of a "flapping" movement, which is blocked in an open conformation upon binding to H3K4me0. Moreover, binding free energy calculations obtained through Molecular Mechanics/Poisson-Boltzmann Surface Area (MM/PBSA) methodology are in good qualitative agreement with experiments and allow dissection of the energetic terms associated with native and alanine mutants of AIRE-PHD1/H3K4me0 complexes. MM/PBSA calculations have also been applied to the energetic analysis of other PHD fingers recognizing H3K4me0. In this case we observe excellent correlation between computed and experimental binding free energies. Overall calculations show that H3K4me0 recognition by PHD fingers relies on compensation of the electrostatic and polar solvation energy terms and is stabilized by non-polar interactions.

Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-α-prolyl-4-hydroxylases

PubMed Central

2004-01-01

An important regulator involved in oxygen-dependent gene expression is the transcription factor HIF (hypoxia-inducible factor), which is composed of an oxygen-sensitive α-subunit (HIF-1α or HIF-2α) and a constitutively expressed β-subunit. In normoxia, HIF-1α is destabilized by post-translational hydroxylation of Pro-564 and Pro-402 by a family of oxygen-sensitive dioxygenases. The three HIF-modifying human enzymes have been termed prolyl hydroxylase domain containing proteins (PHD1, PHD2 and PHD3). Prolyl hydroxylation leads to pVHL (von-Hippel-Lindau protein)-dependent ubiquitination and rapid proteasomal degradation of HIF-1α. In the present study, we report that human PHD2 and PHD3 are induced by hypoxia in primary and transformed cell lines. In the human osteosarcoma cell line, U2OS, selective suppression of HIF-1α expression by RNA interference resulted in a complete loss of hypoxic induction of PHD2 and PHD3. Induction of PHD2 by hypoxia was lost in pVHL-deficient RCC4 cells. These results suggest that hypoxic induction of PHD2 and PHD3 is critically dependent on HIF-α. Using a VHL capture assay, we demonstrate that HIF-α prolyl-4-hydroxylase capacity of cytoplasmic and nuclear protein extracts was enhanced by prolonged exposure to hypoxia. Degradation of HIF-1α after reoxygenation was accelerated, which demonstrates functional relevance of the present results. We propose a direct, negative regulatory mechanism, which limits accumulation of HIF-1α in hypoxia and leads to accelerated degradation on reoxygenation after long-term hypoxia. PMID:15104534

How to Conceptualize and Implement a PhD Program in Health Sciences—The Basel Approach

PubMed Central

Keller, Franziska; Dhaini, Suzanne; Briel, Matthias; Henrichs, Sina; Höchsmann, Christoph; Kalbermatten, Daniel; Künzli, Nino; Mollet, Annette; Puelacher, Christian; Schmidt-Trucksäss, Arno; von Niederhäusern, Belinda; De Geest, Sabina

2018-01-01

Objectives: Over the past decade, several excellent guidelines have been published on how to enhance the quality of PhD education in Europe. Aimed primarily at preparing students for innovative roles in their fields, they include variously structured approaches to curricular offerings, as well as other program components applicable across specialties (eg: supervisor support, scientific conduct, transferable skills). Since 2012, the interdisciplinary PhD Program in Health Sciences (PPHS) at the Faculty of Medicine of the University of Basel in Switzerland has focused on translating these guidelines into a 21st-century health sciences PhD program. Results: The PPHS started in 2012 based on the European Union (EU) guidelines for PhD education. This article describes the resulting interdisciplinary PhD program’s conceptual underpinnings, rationale, structures, and 10 building blocks, like student portfolios, thematic training, interdisciplinary research seminars, student-initiated interdisciplinary activities, financial support of course participation, top-up and extension stipends, PhD supervision, research integrity, alumni follow-up network, and promotional tools including a dedicated website. Students enter from Clinical Research, Medicine Development, Nursing Science, Epidemiology and Public Health including Insurance Medicine, Sport Science (all from the Faculty of Medicine), and Epidemiology (Faculty of Science). Discussion and Conclusion: The Basel PPHS exemplifies state-of-the-art PhD education in Health Sciences based on European guidelines and offers guidance to other groups from conceptualization to rollout of an interdisciplinary health sciences PhD program. PMID:29780889

Challenges of PhD Graduated Nurses for Role Acceptance as a Clinical Educator: A Qualitative Study.

PubMed

Haghighi Moghadam, Yousef; Atashzadeh-Shoorideh, Foroozan; Abbaszadeh, Abbas; Feizi, Aram

2017-06-01

Introduction: Clinical education is the core component of nursing education. PhD graduated nurses who are faculty members can play a main role in clinical instruction. However, there is not clear understanding about the challenges which they may encounter for accepting their role as clinical educator. The aim of this study was to explore the challenges of role acceptance by PhD aduated nurses who are faculty members. Methods: In this qualitative exploratory study a total of 13 participants (8 PhD graduated in nursing, 3 head of departments of nursing, one educational vice chancellor of nursing school, and one nurse) were selected by purposive sampling method. Data were collected by semi-structured, face to face interview and analyzed by conventional content analysis approach developed by Graneheim and Lundman. Results: The main theme emerged from data analysis was "identity threat". This theme had five categories including expectations beyond ability, lack of staff's rely on the performance of PhD graduated nurses, poor clinical competencies, doubtfulness, and obligation. Conclusion: PhD graduated nurses experienced some worries about their role as clinical educators and argued that they have not been prepared for their role. Therefore, policy makers and authorities of nursing schools should support PhD graduated nurses for accepting their new roles as clinical educators. Moreover, some changes in nursing PhD curriculum is needed to improve the clinical competencies of PhD graduated and prepare them for their role as a clinical educator.

Challenges of PhD Graduated Nurses for Role Acceptance as a Clinical Educator: A Qualitative Study

PubMed Central

Haghighi Moghadam, Yousef; Atashzadeh-Shoorideh, Foroozan; Abbaszadeh, Abbas; Feizi, Aram

2017-01-01

Introduction: Clinical education is the core component of nursing education. PhD graduated nurses who are faculty members can play a main role in clinical instruction. However, there is not clear understanding about the challenges which they may encounter for accepting their role as clinical educator. The aim of this study was to explore the challenges of role acceptance by PhD aduated nurses who are faculty members. Methods: In this qualitative exploratory study a total of 13 participants (8 PhD graduated in nursing, 3 head of departments of nursing, one educational vice chancellor of nursing school, and one nurse) were selected by purposive sampling method. Data were collected by semi-structured, face to face interview and analyzed by conventional content analysis approach developed by Graneheim and Lundman. Results: The main theme emerged from data analysis was "identity threat". This theme had five categories including expectations beyond ability, lack of staff’s rely on the performance of PhD graduated nurses, poor clinical competencies, doubtfulness, and obligation. Conclusion: PhD graduated nurses experienced some worries about their role as clinical educators and argued that they have not been prepared for their role. Therefore, policy makers and authorities of nursing schools should support PhD graduated nurses for accepting their new roles as clinical educators. Moreover, some changes in nursing PhD curriculum is needed to improve the clinical competencies of PhD graduated and prepare them for their role as a clinical educator. PMID:28680869

Strategic Studies Quarterly. Volume 8, Number 3, Fall 2014

DTIC Science & Technology

2014-01-01

Michael Guillot Measuring Military Power James Jay Carafano Strategy and Force Planning in a Time of Austerity BG Michael J . Meese, USA, Retired...Hudson, PhD Nori Katagiri, PhD Paul J . Springer, PhD Zachary J . Zwald, PhD Strategic Studies Quarterly (SSQ) (ISSN 1936-1815) is published quarterly...19 BG Michael J . Meese, USA, Retired Pensive Sword: Educating Officers in Austere Times ...................... 30 Stephen D. Chiabotti Feature

A Two-Level Structural Equation Model for Evaluating the External Effectiveness of PhD

ERIC Educational Resources Information Center

Chiandotto, Bruno; Masserini, Lucio

2011-01-01

In recent years the number of PhDs in Italy has significantly grown and purposes of PhD courses have expanded from the traditional ones. The analysis of the contribution of PhD title for job placement and employment condition of PhDs is an important tool for evaluating the quality and the effectiveness of PhD courses. For this reason, knowledge of…

A Brief History of the College of Education's Doctoral Degrees

ERIC Educational Resources Information Center

McEwan, Hunter; Slaughter, Helen

2004-01-01

The College of Education at the University of Hawai'i at Manoa has two doctoral degrees: the PhD in educational psychology and the PhD in education. Both degrees have been in existence for over 30 years. The PhD in education, however, began its life as the EdD and was renamed the PhD in 1999. As two of the articles in this issue make clear…

The Purpose of the Ph.D.--A South African Perspective

ERIC Educational Resources Information Center

Herman, Chaya

2012-01-01

The article sets out to explore how Ph.D. programme leaders in South Africa view the purpose of the Ph.D., and how their views shape their responses to recent policies with regard to the Ph.D. It refers in particular to the vision of the Department of Science and Technology for a five-fold increase in the number of Ph.D. graduates by 2018, and to…

Partnership for development: A peer mentorship model for PhD students.

PubMed

Lewinski, Allison A; Mann, Tara; Flores, Dalmacio; Vance, Ashlee; Bettger, Janet Prvu; Hirschey, Rachel

Formal mentoring relationships socialize Doctor of Philosophy (PhD) students to their current and future roles as nursing scholars. Despite formal mentoring, some students may desire or benefit from additional mentoring in an informal setting. Informal mentoring complements the one-to-one relationship students develop with a primary faculty mentor or dissertation chair. This manuscript describes the development, implementation, and evaluation of a student-driven, peer mentorship model, titled Partnership for Development. This small group, peer mentorship model was implemented in a PhD program at a School of Nursing during an academic year. Five student peer facilitators organized a total of 32 PhD students, 2 post-doctoral associates, and invited 5 faculty to participate. Data includes pre- and post-implementation surveys completed by the students and peer facilitator field notes. Student reported post-participation benefits included: getting to know faculty in an informal setting (n=6), socializing with students from other cohorts (n=6), and obtaining a sense of camaraderie with other PhD students (n=5). We recommend peer mentorship for other PhD programs as a way to socialize PhD students into the role of nurse scientist and assist students during their tenure as a PhD student. Copyright © 2017 Elsevier Inc. All rights reserved.

2012 best practices for repositories collection, storage, retrieval, and distribution of biological materials for research international society for biological and environmental repositories.

PubMed

2012-04-01

Third Edition [Formula: see text] [Box: see text] Printed with permission from the International Society for Biological and Environmental Repositories (ISBER) © 2011 ISBER All Rights Reserved Editor-in-Chief Lori D. Campbell, PhD Associate Editors Fay Betsou, PhD Debra Leiolani Garcia, MPA Judith G. Giri, PhD Karen E. Pitt, PhD Rebecca S. Pugh, MS Katherine C. Sexton, MBA Amy P.N. Skubitz, PhD Stella B. Somiari, PhD Individual Contributors to the Third Edition Jonas Astrin, Susan Baker, Thomas J. Barr, Erica Benson, Mark Cada, Lori Campbell, Antonio Hugo Jose Froes Marques Campos, David Carpentieri, Omoshile Clement, Domenico Coppola, Yvonne De Souza, Paul Fearn, Kelly Feil, Debra Garcia, Judith Giri, William E. Grizzle, Kathleen Groover, Keith Harding, Edward Kaercher, Joseph Kessler, Sarah Loud, Hannah Maynor, Kevin McCluskey, Kevin Meagher, Cheryl Michels, Lisa Miranda, Judy Muller-Cohn, Rolf Muller, James O'Sullivan, Karen Pitt, Rebecca Pugh, Rivka Ravid, Katherine Sexton, Ricardo Luis A. Silva, Frank Simione, Amy Skubitz, Stella Somiari, Frans van der Horst, Gavin Welch, Andy Zaayenga 2012 Best Practices for Repositories: Collection, Storage, Retrieval and Distribution of Biological Materials for Research INTERNATIONAL SOCIETY FOR BIOLOGICAL AND ENVIRONMENTAL REPOSITORIES (ISBER) INTRODUCTION T he availability of high quality biological and environmental specimens for research purposes requires the development of standardized methods for collection, long-term storage, retrieval and distribution of specimens that will enable their future use. Sharing successful strategies for accomplishing this goal is one of the driving forces for the International Society for Biological and Environmental Repositories (ISBER). For more information about ISBER see www.isber.org . ISBER's Best Practices for Repositories (Best Practices) reflect the collective experience of its members and has received broad input from other repository professionals. Throughout this document effective practices are presented for the management of specimen collections and repositories. The term "Best Practice" is used in cases where a level of operation is indicated that is above the basic recommended practice or more specifically designates the most effective practice. It is understood that repositories in certain locations or with particular financial constraints may not be able to adhere to each of the items designated as "Best Practices". Repositories fitting into either of these categories will need to decide how they might best adhere to these recommendations within their particular circumstances. While adherence to ISBER Best Practices is strictly on a voluntary basis, it is important to note that some aspects of specimen management are governed by national/federal, regional and local regulations. The reader should refer directly to regulations for their national/federal, regional and local requirements, as appropriate. ISBER has strived to include terminology appropriate to the various specimen types covered under these practices, but here too, the reader should take steps to ensure the appropriateness of the recommendations to their particular repository type prior to the implementation of any new approaches. Important terms within the document are italicized when first used in a section and defined in the glossary. The ISBER Best Practices are periodically reviewed and revised to reflect advances in research and technology. The third edition of the Best Practices builds on the foundation established in the first and second editions which were published in 2005 and 2008, respectively.

The Importance of MS PHD'S and SEEDS Mentoring and Professional Development Programs in the Retenion of Underrepresented Minorities in STEM Fields

NASA Astrophysics Data System (ADS)

Strickland, J.; Johnson, A.; Williamson Whitney, V.; Ricciardi, L.

2012-12-01

According to a recent study by the National Academy of Sciences, underrepresented minority (URM) participation in STEM disciplines represents approximately one third of the URM population in the U.S. Thus, the proportion of URM in STEM disciplines would need to triple in order to reflect the demographic makeup in the U.S. Individual programs targeting the recruitment and retention of URM students in STEM have demonstrated that principles of mentoring, community building, networking, and professional skill development are crucial in encouraging URM students to remain in STEM disciplines thereby reducing this disparity in representation. However, to paraphrase an old African proverb, "it takes a village to nurture and develop a URM student entering into the STEM community." Through programs such as the Institute for Broadening Participation's Minorities Striving and Pursuing Higher Degrees of Success (MS PHD'S) Professional Development Program in Earth system science and the Ecological Society of America's Strategies for Ecology Education, Diversity and Sustainability (SEEDS), URM students are successfully identifying and benefitting from meaningful opportunities to develop the professional skills and strategies needed to achieve their academic and career goals. Both programs share a philosophy of professional development, reciprocal mentoring, field trips, internships, employment, research partnerships, collaborations, fellowships, scholarships, grants, and professional meeting travel awards to support URM student retention in STEM. Both programs share a mission to bring more diversity and inclusivity into STEM fields. Both programs share a history of success at facilitating the preparation and advancement of URM students. This success has been documented with the multitude of URM students that have matriculated through the programs and are now actively engaged in the pursuit of advanced degrees in STEM or entering the STEM workforce. Anonymous surveys from participants affirms that these programs provided an excellent environment for advancing interest in, and knowledge of STEM, and for influencing academic career goals for participants. These programs are models and reflect the importance of providing diversity, mentoring and professional development programs to broaden the participation and retention of URM students in STEM fields.

Masters International Program in Natural Hazards: a joint program between Michigan Tech and US Peace Corps begins move to work in Indonesia

NASA Astrophysics Data System (ADS)

Rose, W. I.; Carn, S. A.; Waite, G. P.; Gierke, J. S.; Wellik, J. J.

2011-12-01

We are in the seventh year of developing a unique graduate degree program in which each student serves in the U.S. Peace Corps for two years while conducting his/her field research. Our program allows candidates to work on natural hazard mitigation projects in a country where natural hazards are important parts of life. For US students, living abroad provides a vital broadening experience and the Peace Corps emphasis on social context adds cultural understanding to their hazards work. Up until now, we have mostly worked in Central America, and 33 students have enrolled in the program. The greatest focus to date has been in Volcanic Hazards, including slope stability and debris flows, and our work is fostering long-term infrastructure-building relationships with partner agencies within the 8 countries where we have worked. This year we sent a student (Jay Wellik) to a Peace Corps site in East Java, Indonesia where he will work with schools in his village and commute weekly to the Raung Observatory Post to work with CVGHM scientists on volcano seismology and public outreach projects.. We recruit 4-6 new students each year, and we hope more will soon be in Indonesia as Peace Corps expands their new program in that country. Although the Peace Corps Masters International (PCMI) students must be US citizens, we also have regular undergraduate and graduate (MS and PhD) degree students in geology, geological engineering and geophysics who come from all over the world. We are especially interested in people from partner Peace Corps countries. Annually our natural-hazards group consists of 5 faculty, 2 post-doctoral researchers, several Ph.D and traditional M.S. students, 12 PCMI students, and roughly 20 undergraduate students. Support for our program has come from NSF and we have also benefitted from a supportive cooperation with USGS VDAP. In the past two years we have built a complementary dual degree partnership with the Université Blaise-Pascal, Clermont Ferrand (France), and Universitá degli Studi di Milano - Bicocca (Italy) , which allows for a strong European connection to this international work.

Homeostatic and Circadian Modulation of Cognition: Integrating Mathematical and Computational Modeling Approaches

DTIC Science & Technology

2012-08-20

Leonid V. Kalachev, Ph.D. (University of Montana, not supported on grant) Daniel J. Mollicone, Ph.D. ( Pulsar Informatics, Inc., not supported on grant...project to Pulsar Informatics, Inc., who are providing an implementation suitable for integration with crew rostering to the U.S. Navy (key...individuals involved: Daniel Mollicone, Ph.D. and Mike Stubna, Ph.D. of Pulsar Informatics, Inc.).  We transitioned a numerical library for the mathematical

Tranexamic Acid for Trauma Patients: A Critical Review of the Literature

DTIC Science & Technology

2011-07-01

REVIEW ARTICLE Tranexamic Acid for Trauma Patients: A Critical Review of the Literature Andrew P. Cap, MD, PhD, David G. Baer, PhD, Jean A. Orman...MPH, ScD, James Aden, PhD, Kathy Ryan, PhD, and Lorne H. Blackbourne, MD Background: Tranexamic acid (TXA) is an antifibrinolytic that inhibits both...prospective clinical evidence to support this application. Key Words: Tranexamic acid , Antifibrinolytic agents, Hemorrhage/drug therapy, Wounds and injuries

International Humanitarian Award.

PubMed

2017-12-01

The International Humanitarian Award recognizes extraordinary humanitarian services and activism by psychologists, including professional and volunteer work conducted primarily in the field with underserved populations. Award recipients are psychologists who, by their extraordinary service at a difficult time, improve the lives and contribute to the well-being of people in a large or small geographic area anywhere in the world. The 2017 recipient of the APA International Humanitarian Award was selected by the 2016 Committee on International Relations in Psychology (CIRP). The members of the 2016 CIRP were Melissa Morgan Consoli, PhD, and Arpana G. Inman, PhD (Co-chairs); Rehman Abdulrehman, PhD; Gonzalo Bacigalupe, EdD; Frederic Bemak, EdD; Brigitte Khoury, PhD; Susan Nolan, PhD; Nancy Sidun, PsyD; and Danny Wedding, PhD. Dr. Morgan Consoli, Dr. Inman, Dr. Nolan, and Doctor Sidun were members of the subcommittee for the 2017 award. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Qualitative methods in PhD theses from general practice in Scandinavia.

PubMed

Malterud, Kirsti; Hamberg, Katarina; Reventlow, Susanne

2017-12-01

Qualitative methodology is gaining increasing attention and esteem in medical research, with general practice research taking a lead. With these methods, human and social interaction and meaning can be explored and shared by systematic interpretation of text from talk, observation or video. Qualitative studies are often included in Ph.D. theses from general practice in Scandinavia. Still, the Ph.D. programs across nations and institutions offer only limited training in qualitative methods. In this opinion article, we draw upon our observations and experiences, unpacking and reflecting upon values and challenges at stake when qualitative studies are included in Ph.D. theses. Hypotheses to explain these observations are presented, followed by suggestions for standards of evaluation and improvement of Ph.D. programs. The authors conclude that multimethod Ph.D. theses should be encouraged in general practice research, in order to offer future researchers an appropriate toolbox.

Qualitative methods in PhD theses from general practice in Scandinavia

PubMed Central

Malterud, Kirsti; Hamberg, Katarina; Reventlow, Susanne

2017-01-01

Qualitative methodology is gaining increasing attention and esteem in medical research, with general practice research taking a lead. With these methods, human and social interaction and meaning can be explored and shared by systematic interpretation of text from talk, observation or video. Qualitative studies are often included in Ph.D. theses from general practice in Scandinavia. Still, the Ph.D. programs across nations and institutions offer only limited training in qualitative methods. In this opinion article, we draw upon our observations and experiences, unpacking and reflecting upon values and challenges at stake when qualitative studies are included in Ph.D. theses. Hypotheses to explain these observations are presented, followed by suggestions for standards of evaluation and improvement of Ph.D. programs. The authors conclude that multimethod Ph.D. theses should be encouraged in general practice research, in order to offer future researchers an appropriate toolbox. PMID:29094644

Skill set development of doctoral and post-doctoral graduates in life sciences.

PubMed

Kanwar, R S

2010-01-01

Doctoral and post-doctoral training programs at leading research universities in the USA are highly important in generating the much needed knowledge in science, technology, engineering, and mathematics for keeping rural and urban economies strong and societies healthy and prosperous. In addition, innovative graduate and post doctoral research programs are the driving engines of the success of U.S. economy and have made the U.S. the most successful model of generating new knowledge in the broader areas of life sciences (and agricultural education, research, and extension). We need to do everything in our power to make these training programs innovative, collaborative, independent, and resourceful so that students are trained in different disciplines making them more flexible within a range of challenges and opportunities. The training programs must empower students to solve complex and interdisciplinary problems of the society in 21st century and make our students competitive within a global economic system, to improve the health of the nation's economy. If our land grant schools and institutions of higher learning are not preparing doctoral students to be globally competitive scientists to create new knowledge and technologies to solve complex and interdisciplinary problems of the 21st century, then either we need to redefine the mission of our land grant system or we risk losing our role to serve the public and industry effectively. Doctoral and post doctoral students should be given the needed skills and experiences to prepare them for tenure track faculty jobs at leading US Universities in the 21st century as well as prepare them for the world outside of academia. I would say minimum competency skills are needed as "bare survival skills" for all doctoral students to become successful after obtaining PhD degrees. Today's PhD students will be working in a global but highly competitive, rapidly changing, and complex world. It is no longer enough to be a good researcher and a good teacher; researchers and teachers must be good team players and leaders to lead interdisciplinary research programs, and exceptional managers to effectively manage their research staff, MS and PhD students, and post doctoral researchers. Doctoral students have exceptional opportunities during their PhD degree programs to acquire these skills from their world class supervisors and participate in available workshops on how to develop successful and winning grant proposals, improving communication skills, and participate in "future faculty programs" on their campuses.

Doctoral Programs to Train Future Leaders in Clinical and Translational Science

PubMed Central

Switzer, Galen E.; Robinson, Georgeanna F.W.B.; Rubio, Doris M.; Fowler, Nicole R.; Kapoor, Wishwa N.

2013-01-01

Purpose Although the National Institutes of Health (NIH) has made extensive investments in educational programs related to clinical and translational science (CTS), there has been no systematic investigation of the number and characteristics of PhD programs providing training to future leaders in CTS. The authors undertook to determine the number of institutions that, having had received NIH-funded Clinical and Translational Science Awards (CTSAs), currently had or were developing PhD programs in CTS; to examine differences between programs developed before and after CTSA funding; and to provide detailed characteristics of new programs. Method In 2012, CTS program leaders at the 60 CTSA-funded institutions completed a cross-sectional survey focusing on four key domains related to PhD programs in CTS: program development and oversight; students; curriculum and research; and milestones. Results Twenty-two institutions had fully developed PhD programs in CTS, and 268 students were earning a PhD in this new field; 13 institutions were planning a PhD program. New programs were more likely to have fully developed PhD competencies and more likely to include students in medical school, students working only on their PhD, students working on a first doctoral degree, and students working in T1 translational research. They were less likely to include physicians and students working in clinical or T2 research. Conclusions Although CTS PhD programs have similarities, they also vary in their characteristics and management of students. This may be due to diversity in translational science itself or to the relative infancy of CTS as a discipline. PMID:23899901

Joanne Simpson (1923-2010)

NASA Astrophysics Data System (ADS)

Garstang, Michael

2010-06-01

Joanne Gerould Simpson died at George Washington University Hospital, Washington, D. C., on 4 March 2010, just a few weeks short of her 87th birthday. She was a longtime member and Fellow (1994) of AGU and a world-renowned atmospheric scientist. She began her research career at Woods Hole Oceanographic Institution, on Cape Cod, Massachusetts, and continued at such distinguished institutions as University of California, Los Angeles; the Experimental Meteorology Laboratory of the National Oceanic and Atmospheric Administration (NOAA), in Miami, Fla.; University of Virginia, Charlottesville; and finally as chief scientist for meteorology at NASA Goddard Laboratory for Atmospheres, Greenbelt, Md. Joanne was born in Boston, Mass., and as a result of her early exposure to the ocean and atmosphere and her love for sailing and flying, she began her undergraduate work at University of Chicago in astrophysics. The advent of World War II, however, drew her into training programs in meteorology and ultimately to graduate degrees in meteorology under Carl Rossby (M.S.), and Herbert Riehl (Ph.D.). In 1949 she became the first woman to earn a Ph.D. in meteorology. These early interests focused her attention on the disparate time and space scales of motion that connect and distribute the Sun's energy to power the Earth's atmosphere. In her early research with Riehl, Joanne saw deep penetrating clouds as the conduits or “hot towers” that connect the surface to the high atmosphere. These clouds represented the “firebox” of the atmospheric heat engine and coupled the tropics to the poles.

STS-103 MS Clervoy and Nicollier and Commander Brown look over Discovery after landing

NASA Technical Reports Server (NTRS)

1999-01-01

After landing at the Shuttle Landing Facility, STS-103 Mission Specialists Jean-Francois Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency, listen to a comment by Commander Curtis L. Brown Jr. while looking over the orbiter Discovery. Other members of the crew are Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), and John M. Grunsfeld (Ph.D.). The crew of seven completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 EST and wheel stop at 7:01:34 EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history.

STS-103 Pilot Scott Kelly and MS John Grunsfeld try on oxygen masks

NASA Technical Reports Server (NTRS)

1999-01-01

In the bunker at Launch Pad 39B, STS-103 Pilot Scott J. Kelly (left) and Mission Specialist John M. Grunsfeld (Ph.D.) (right) try on oxygen masks during Terminal Countdown Demonstration Test (TCDT) activities. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. Other crew members taking part are Commander Curtis L. Brown Jr. and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), and Jean-Frangois Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

Understanding ligand effects in gold clusters using mass spectrometry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Grant E.; Laskin, Julia

This review summarizes recent research on the influence of phosphine ligands on the size, stability, and reactivity of gold clusters synthesized in solution. Sub-nanometer clusters exhibit size- and composition-dependent properties that are unique from those of larger nanoparticles. The highly tunable properties of clusters and their high surface-to-volume ratio make them promising candidates for a variety of technological applications. However, because “each-atom-counts” toward defining cluster properties it is critically important to develop robust synthesis methods to efficiently prepare clusters of predetermined size. For decades phosphines have been known to direct the size-selected synthesis of gold clusters. Despite the preparation ofmore » numerous species it is still not understood how different functional groups at phosphine centers affect the size and properties of gold clusters. Using electrospray ionization mass spectrometry (ESI-MS) it is possible to characterize the effect of ligand substitution on the distribution of clusters formed in solution at defined reaction conditions. In addition, ligand exchange reactions on preformed clusters may be monitored using ESI-MS. Collision induced dissociation (CID) may also be employed to obtain qualitative insight into the fragmentation of mixed ligand clusters and the relative binding energies of differently substituted phosphines. Quantitative ligand binding energies and cluster stability may be determined employing surface induced dissociation (SID) in a custom-built Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR-MS). Rice-Ramsperger-Kassel-Marcus (RRKM) based modeling of the SID data allows dissociation energies and entropy values to be extracted that may be compared with the results of high-level theoretical calculations. The charge reduction and reactivity of atomically precise gold clusters, including partially ligated species generated in the gas-phase by in source CID, on well-defined surfaces may be explored using ion soft landing (SL) in a custom-built instrument combined with in situ time of flight secondary ion mass spectrometry (TOF-SIMS). Jointly, this multipronged experimental approach allows characterization of the full spectrum of relevant phenomena including cluster synthesis, ligand exchange, thermochemistry, surface immobilization, and reactivity. The fundamental insights obtained from this work will facilitate the directed synthesis of gold clusters with predetermined size and properties for specific applications.« less

A Navy Escrow Account: Increasing Financial Flexibility

DTIC Science & Technology

2003-06-01

generate cost savings and the means by which those funds could be recapitalized. The creation of an escrow account coincides with the Navy’s Sea...Navy escrow account , as envisioned, would provide financial managers with the incentive to generate cost savings and the means by which those funds...MONTEREY, CALIFORNIA CONRAD ESSAY A Navy Escrow Account : Increasing Financial Flexibility By: Commander Marcus A. Pritchard

Quenching of Emission and of Photochemistry for Aqueous Rh(NH3)5Cl(2+).

DTIC Science & Technology

1979-04-01

Hueneme, CalifornIa 93041 Attn: Dr. R. 3. Marcus 1 Attn: Mr. W. S. Haynes ONR Branch Offi ce Professor 0. Hein7 760 Market Street , Rm. 447...Peebles 1 WashI ngton, D.C. 20380 Directo r, Naval Research Laboratory Offi ce of Naval Researc hWashington, D.C. 20390 Arlington, VIrginia 22217

Electron transfer rate on mixed valence states of Class II/III transition for N, N'-diphenyl-1,4-phenylenediamine structures as a polyaniline unit

NASA Astrophysics Data System (ADS)

Nishiumi, Toyohiko; Nomura, Yasuhiro; Higuchi, Masayoshi; Yamamoto, Kimihisa

2003-08-01

The first example of the determination of the electron transfer rate ( λ, V, Δ G*, kth) for N, N'-diphenyl-1,4-phenylenediamine derivatives using the Marcus-Hush theory is described. These results were in good agreement with the ones obtained using variable-temperature IR spectra measurements.

Theory, Observation, and Validation: Commentary on Almond, Kim, Velasquez, & Shute

ERIC Educational Resources Information Center

Markus, Keith A.

2014-01-01

Keith Marcus congratulates Almond et al. on an interesting article bringing together two topics that are important to the field of testing. He states that some aspects of the exposition came across as not yet fully developed, as if the manuscript had been hurried to press. In this commentary, he attempts to expand aspects of the article, which he…

78 FR 18340 - The Neiman Marcus Group, Inc.; Dr.Jays.com, Inc., Eminent, Inc.; Analysis of Proposed Consent...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-26

... heightened security screening. As a result, we encourage you to submit your comments online. To make sure...'' or ``Eminent, File No. 122 3065'' on your comment and file your comment online at https://ftcpublic... prefer to file your comment on paper, mail or deliver your comment to the following address: Federal...

77 FR 6065 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-07

... day public comment period. L-DEO plans to use one source vessel, the R/V Marcus G. Langseth (Langseth... (km) 1,511.9 nautical miles [nmi]) of transect lines (including turns) in the study area. The seismic... involve one source vessel, the Langseth. The Langseth will deploy an array of 36 airguns as an energy...

76 FR 77782 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-14

...) during the study. The shot interval will be relatively short, approximately 15 to 18 seconds (s), for the... than the one provided here. Comments sent via email, including all attachments, must not exceed a 10... 21, 2012. L-DEO plans to use one source vessel, the R/V Marcus G. Langseth (Langseth) and a seismic...

Sorry Dave, I’m Afraid I Can’t Do That: Explaining Unachievable Robot Tasks using Natural Language

DTIC Science & Technology

2013-06-24

processing components used by Brooks et al. [6]: the Bikel parser [3] combined with the null element (understood subject) restoration of Gabbard et al...Intelligent Robots and Systems (IROS), pages 1988 – 1993, 2010. [12] Ryan Gabbard , Mitch Marcus, and Seth Kulick. Fully parsing the Penn Treebank. In Human

Geometric Computation of Human Gyrification Indexes from Magnetic Resonance Images

DTIC Science & Technology

2009-04-01

GEOMETRIC COMPUTATION OF HUMAN GYRIFICATION INDEXES FROM MAGNETIC RESONANCE IMAGES By Shu Su Tonya White Marcus Schmidt Chiu-Yen Kao and Guillermo...00-2009 to 00-00-2009 4. TITLE AND SUBTITLE Geometric Computation of Human Gyrification Indexes from Magnetic Resonance Images 5a. CONTRACT NUMBER... Geometric Computation of Gyrification Indexes Chiu-Yen Kao 1 Geometric Computation of Human Gyrification

Dog Is a Dog Is a Dog: Infant Rule Learning Is Not Specific to Language

ERIC Educational Resources Information Center

Saffran, Jenny R.; Pollak, Seth D.; Seibel, Rebecca L.; Shkolnik, Anna

2007-01-01

Human infants possess powerful learning mechanisms used for the acquisition of language. To what extent are these mechanisms domain specific? One well-known infant language learning mechanism is the ability to detect and generalize rule-like similarity patterns, such as ABA or ABB [Marcus, G. F., Vijayan, S., Rao, S. B., & Vishton, P. M. (1999).…

Marcuse, Bloch and Freire: Reinvigorating a Pedagogy of Hope

ERIC Educational Resources Information Center

Van Heertum, Richard

2006-01-01

Critique of the current order of things is a necessary starting point for any project for radical change. Without an analysis of what is wrong, it is hard to convince anyone that change is necessary. And yet critique alone rarely inspires people to act. We need something to fight for as well as against. The article looks at the centrality of hope…

Toward a Broader Dialectic: Joining Marxism with Mailer to Forge a Multilectics That Advances Teaching and Learning

ERIC Educational Resources Information Center

Fellner, Gene

2014-01-01

I contrast the lenses that Norman Mailer, Herbert Marcuse, and Karl Marx bring to their analyses of social life, exploring the contributions and limits of their respective approaches. I then propose what I call a "multilectical" theoretical lens that encompasses the strengths of all three and leans on the insights of post-Marxist…

Information from Multiple Modalities Helps 5-Month-Olds Learn Abstract Rules

ERIC Educational Resources Information Center

Frank, Michael C.; Slemmer, Jonathan A.; Marcus, Gary F.; Johnson, Scott P.

2009-01-01

By 7 months of age, infants are able to learn rules based on the abstract relationships between stimuli ( Marcus et al., 1999 ), but they are better able to do so when exposed to speech than to some other classes of stimuli. In the current experiments we ask whether multimodal stimulus information will aid younger infants in identifying abstract…

Organtropic Metastatic Secretomes and Exosomes in Breast Cancer

DTIC Science & Technology

2016-10-01

MD, PhD CONTRACTING ORGANIZATION: Joan & Sanford I Weill Medical College of Cornell University New York, NY 10065 REPORT DATE: October 2016 TYPE...STATEMENT: Approved for Public Release; Distribution Unlimited The views, opinions and/or findings contained in this report are those of the author( s ) and...Cancer 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER David Lyden, MD, PhD, Ayuko Hoshino, PhD, Irina Matei, PhD

The Role of the Novel Nuclear Tyrosine Kinase, RAK, in Breast Cancer Biology (TR950012)

DTIC Science & Technology

1999-07-01

INVESTIGATOR: Paul M. Armistead, Ph.D. Holden H. Thorp, Ph.D. CONTRACTING ORGANIZATION : University of North Carolina Chapel Hill, North Carolina 27599...Biology (TR950012) 6. AUTHOR(S) Paul M. Armistead, Ph.D.. Holden H. Thorp, Ph.D. 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) University of...Materiel Command Fort Detrick, Maryland 21702-5012 5. FUNDING NUMBERS DAMD17-96-1-6067 8. PERFORMING ORGANIZATION REPORT NUMBER 10. SPONSORING

Distal [FeS]-Cluster Coordination in [NiFe]-Hydrogenase Facilitates Intermolecular Electron Transfer

PubMed Central

Petrenko, Alexander; Stein, Matthias

2017-01-01

Biohydrogen is a versatile energy carrier for the generation of electric energy from renewable sources. Hydrogenases can be used in enzymatic fuel cells to oxidize dihydrogen. The rate of electron transfer (ET) at the anodic side between the [NiFe]-hydrogenase enzyme distal iron–sulfur cluster and the electrode surface can be described by the Marcus equation. All parameters for the Marcus equation are accessible from Density Functional Theory (DFT) calculations. The distal cubane FeS-cluster has a three-cysteine and one-histidine coordination [Fe4S4](His)(Cys)3 first ligation sphere. The reorganization energy (inner- and outer-sphere) is almost unchanged upon a histidine-to-cysteine substitution. Differences in rates of electron transfer between the wild-type enzyme and an all-cysteine mutant can be rationalized by a diminished electronic coupling between the donor and acceptor molecules in the [Fe4S4](Cys)4 case. The fast and efficient electron transfer from the distal iron–sulfur cluster is realized by a fine-tuned protein environment, which facilitates the flow of electrons. This study enables the design and control of electron transfer rates and pathways by protein engineering. PMID:28067774

The status of PhD education in economic, social, and administrative sciences between 2005 and 2008.

PubMed

Farley, Joel F; Wang, Chi-Chuan; Blalock, Susan J

2010-09-10

To describe the funding, education, enrollment, and graduation patterns from economic, social, and administrative sciences PhD programs in colleges and schools of pharmacy in the United States. Economic, social, and administrative sciences PhD programs were identified from the American Association of Colleges of Pharmacy (AACP) Web site. A 41-item online survey instrument was sent to the director of graduate studies of each identified program. Only programs offering a PhD degree were included in the study. Of the 26 programs surveyed, 20 (77%) provided useable responses to the survey instrument. Approximately 91% of PhD programs guarantee funding to incoming students with an average commitment of 2.9 years. On average, students were paid a stipend of $18,000 per year for commitments to research and teaching assistantships, each averaging approximately 2 years in length. Programs admitted an average of 3.5 students per year and graduated approximately 85% of entering students. The majority of students are non-US citizens and accept positions in either academic or industrial positions after graduation. Most economic, social, and administrative sciences PhD programs guarantee funding to incoming PhD candidates. Programs offering funding packages significantly below the average may be at a competitive disadvantage. It is unclear whether the number of students graduating from PhD programs is adequate to fulfill academic and industrial needs.

Short Hairpin RNA Gene Silencing of Prolyl Hydroxylase-2 with a Minicircle Vector Improves Neovascularization of Hindlimb Ischemia

PubMed Central

Lijkwan, Maarten A.; Hellingman, Alwine A.; Bos, Ernst J.; van der Bogt, Koen E.A.; Huang, Mei; Kooreman, Nigel G.; de Vries, Margreet R.; Peters, Hendrika A.B.; Robbins, Robert C.; Quax, Paul H.A.

2014-01-01

Abstract In this study, we target the hypoxia inducible factor-1 alpha (HIF-1-alpha) pathway by short hairpin RNA interference therapy targeting prolyl hydroxylase-2 (shPHD2). We use the minicircle (MC) vector technology as an alternative for conventional nonviral plasmid (PL) vectors in order to improve neovascularization after unilateral hindlimb ischemia in a murine model. Gene expression and transfection efficiency of MC and PL, both in vitro and in vivo, were assessed using bioluminescence imaging (BLI) and firefly luciferase (Luc) reporter gene. C57Bl6 mice underwent unilateral electrocoagulation of the femoral artery and gastrocnemic muscle injection with MC-shPHD2, PL-shPHD2, or phosphate-buffered saline (PBS) as control. Blood flow recovery was monitored using laser Doppler perfusion imaging, and collaterals were visualized by immunohistochemistry and angiography. MC-Luc showed a 4.6-fold higher in vitro BLI signal compared with PL-Luc. BLI signals in vivo were 4.3×105±3.3×105 (MC-Luc) versus 0.4×105±0.3×105 (PL-Luc) at day 28 (p=0.016). Compared with PL-shPHD2 or PBS, MC-shPHD2 significantly improved blood flow recovery, up to 50% from day 3 until day 14 after ischemia induction. MC-shPHD2 significantly increased collateral density and capillary density, as monitored by alpha-smooth muscle actin expression and CD31+ expression, respectively. Angiography data confirmed the histological findings. Significant downregulation of PHD2 mRNA levels by MC-shPHD2 was confirmed by quantitative polymerase chain reaction. Finally, Western blot analysis confirmed significantly higher levels of HIF-1-alpha protein by MC-shPHD2, compared with PL-shPHD2 and PBS. This study provides initial evidence of a new potential therapeutic approach for peripheral artery disease. The combination of HIF-1-alpha pathway targeting by shPHD2 with the robust nonviral MC plasmid improved postischemic neovascularization, making this approach a promising potential treatment option for critical limb ischemia. PMID:24090375

The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.

PubMed

He, Chao; Li, Fudong; Zhang, Jiahai; Wu, Jihui; Shi, Yunyu

2013-02-15

The NSD (nuclear receptor SET domain-containing) family members, consisting of NSD1, NSD2 (MMSET/WHSC1), and NSD3 (WHSC1L1), are SET domain-containing methyltransferases and aberrant expression of each member has been implicated in multiple diseases. They have specific mono- and dimethylase activities for H3K36, whereas play nonredundant roles during development. Aside from the well characterized catalytic SET domain, NSD proteins have multiple potential chromatin-binding motifs that are clinically relevant, including the fifth plant homeodomain (PHD5) and the adjacent Cys-His-rich domain (C5HCH) located at the C terminus. Herein, we report the crystal structures of the PHD5-C5HCH module of NSD3, in the free state and in complex with H3(1-7) (H3 residues 1-7), H3(1-15) (H3 residues 1-15), and H3(1-15)K9me3 (H3 residues 1-15 with trimethylation on K9) peptides. These structures reveal that the PHD5 and C5HCH domains fold into a novel integrated PHD-PHD-like structural module with H3 peptide bound only on the surface of PHD5 and provide the molecular basis for the recognition of unmodified H3K4 and trimethylated H3K9 by NSD3 PHD5. Structural studies and binding assays show that differences exist in histone binding specificity of the PHD5 domain between three members of the NSD family. For NSD2, the PHD5-C5HCH:H3 N terminus interaction is largely conserved, although with a stronger preference for unmethylated H3K9 (H3K9me0) than trimethylated H3K9 (H3K9me3), and NSD1 PHD5-C5HCH does not bind to H3 peptides. Our results shed light on how NSD proteins that mediate H3K36 methylation are localized to specific genomic sites and provide implications for the mechanism of functional diversity of NSD proteins.

Factors that facilitate or inhibit interest of domestic students in the engineering PhD: A mixed methods study

NASA Astrophysics Data System (ADS)

Howell Smith, Michelle C.

Given the increasing complexity of technology in our society, the United States has a growing demand for a more highly educated technical workforce. Unfortunately, the proportion of United States citizens earning a PhD in engineering has been declining and there is concern about meeting the economic, national security and quality of life needs of our country. This mixed methods sequential exploratory instrument design study identified factors that facilitate or inhibit interest in engineering PhD programs among domestic engineering undergraduate students in the United States. This study developed a testable theory for how domestic students become interested in engineering PhD programs and a measure of that process, the Exploring Engineering Interest Inventory (EEII). The study was conducted in four phases. The first phase of the study was a qualitative grounded theory exploration of interest in the engineering PhD. Qualitative data were collected from domestic engineering students, engineering faculty and industry professional who had earned a PhD in engineering. The second phase, instrument development, developed the Exploring Engineering Interest Inventory (EEII), a measurement instrument designed with good psychometric properties to test a series of preliminary hypotheses related to the theory generated in the qualitative phase. In the third phase of the study, the EEII was used to collect data from a larger sample of junior and senior engineering majors. The fourth phase integrated the findings from the qualitative and quantitative phases. Four factors were identified as being significant influences of interest in the engineering PhD: Personal characteristics, educational environment, misperceptions of the economic and personal costs, and misperceptions of engineering work. Recommendations include increasing faculty encouragement of students to pursue an engineering PhD and programming to correct the misperceptions of the costs of the engineering PhD and the nature of the work that PhD engineers do. The tested model provides engineering educators with information to help them prioritize their efforts to increase interest in the engineering PhD among domestic students.