21 CFR 113.60 - Containers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Containers. 113.60 Section 113.60 Food and Drugs... CONSUMPTION THERMALLY PROCESSED LOW-ACID FOODS PACKAGED IN HERMETICALLY SEALED CONTAINERS Control of Components, Food Product Containers, Closures, and In-Process Materials § 113.60 Containers. Link to an...

TECHNICAL AND REGULATORY CONSIDERATIONS IN USING FREIGHT CONTAINERS AS INDUSTRIAL PACKAGES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Opperman, E; Mark Hawk, M; Ron Natali, R

2007-10-16

The United States (US) Department of Energy (DOE), Office of Environmental Management (EM), is actively pursuing activities to reduce the radiological risk and clean up the environmental legacy of the nation's nuclear weapons programs. EM has made significant progress in recent years in the clean-up and closure of sites and is also focusing on longer-term activities necessary for the completion of the clean-up program. The packaging and transportation of contaminated demolition debris and low-level waste (LLW) materials in a safe and cost-effective manner are essential in completing this mission. Toward this end, the US Department of Transportation's (DOT) Final Rulemore » on Hazardous Materials Regulation Final Rule issued January 26, 2004, included a new provision authorizing the use of Freight Containers (e.g., 20 and 40-foot ISO Containers) as Industrial Packages Type 1, 2, or 3 (IP-1, IP-2, and IP-3). This paper will discuss the technical and regulatory considerations in using these newly authorized and large packages for the packaging and transportation of LLW materials.« less

49 CFR 178.601 - General requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... proportion to the reduction in volume. (4) Variation 4. Variations are permitted in outer packagings of a... steel; (viii) An increase greater than 10% or any decrease in the steel thickness of the head, body, or... body), type (e.g., mechanically seamed or welded flange), and materials of closure (other than the...

49 CFR 178.601 - General requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... proportion to the reduction in volume. (4) Variation 4. Variations are permitted in outer packagings of a... steel; (viii) An increase greater than 10% or any decrease in the steel thickness of the head, body, or... body), type (e.g., mechanically seamed or welded flange), and materials of closure (other than the...

49 CFR 178.601 - General requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... proportion to the reduction in volume. (4) Variation 4. Variations are permitted in outer packagings of a... steel; (viii) An increase greater than 10% or any decrease in the steel thickness of the head, body, or... body), type (e.g., mechanically seamed or welded flange), and materials of closure (other than the...

21 CFR 212.50 - What production and process controls must I have?

Code of Federal Regulations, 2010 CFR

2010-04-01

... containers, closures, and packaging materials, including a specimen or copy of each label and all other..., the name and radioactivity or other measurement of each active pharmaceutical ingredient and each... active pharmaceutical ingredient and each inactive ingredient per batch or per unit of radioactivity or...

21 CFR 212.50 - What production and process controls must I have?

Code of Federal Regulations, 2011 CFR

2011-04-01

... containers, closures, and packaging materials, including a specimen or copy of each label and all other... radioactivity or other measurement of each active pharmaceutical ingredient and each inactive ingredient per... active pharmaceutical ingredient and each inactive ingredient per batch or per unit of radioactivity or...

Status of Progress Made Toward Preliminary Design Concepts for the Inventory in Select Media for DOE-Managed HLW/SNF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matteo, Edward N.; Hardin, Ernest L.; Hadgu, Teklu

As the title suggests, this report provides a summary of the status and progress for the Preliminary Design Concepts Work Package. Described herein are design concepts and thermal analysis for crystalline and salt host media. The report concludes that thermal management of defense waste, including the relatively small subset of high thermal output waste packages, is readily achievable. Another important conclusion pertains to engineering feasibility, and design concepts presented herein are based upon established and existing elements and/or designs. The multipack configuration options for the crystalline host media pose the greatest engineering challenges, as these designs involve large, heavy wastemore » packages that pose specific challenges with respect to handling and emplacement. Defense-related Spent Nuclear Fuel (DSNF) presents issues for post-closure criticality control, and a key recommendation made herein relates to the need for special packaging design that includes neutron-absorbing material for the DSNF. Lastly, this report finds that the preliminary design options discussed are tenable for operational and post-closure safety, owing to the fact that these concepts have been derived from other published and well-studied repository designs.« less

A Fruit of Yucca Mountain: The Remote Waste Package Closure System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kevin Skinner; Greg Housley; Colleen Shelton-Davis

2011-11-01

Was the death of the Yucca Mountain repository the fate of a technical lemon or a political lemon? Without caution, this debate could lure us away from capitalizing on the fruits of the project. In March 2009, Idaho National Laboratory (INL) successfully demonstrated the Waste Package Closure System, a full-scale prototype system for closing waste packages that were to be entombed in the now abandoned Yucca Mountain repository. This article describes the system, which INL designed and built, to weld the closure lids on the waste packages, nondestructively examine the welds using four different techniques, repair the welds if necessary,more » mitigate crack initiating stresses in the surfaces of the welds, evacuate and backfill the packages with an inert gas, and perform all of these tasks remotely. As a nation, we now have a proven method for securely sealing nuclear waste packages for long term storage—regardless of whether or not the future destination for these packages will be an underground repository. Additionally, many of the system’s features and concepts may benefit other remote nuclear applications.« less

The impact of primary packaging on the quality of parenteral products.

PubMed

Solomun, Ljiljana; Ibric, Svetlana; Boltic, Zorana; Djuric, Zorica; Stupar, Biljana

2008-11-04

The unique approach in manufacturing of pharmaceutical dosage forms of active substances known to be unstable in aqueous solution is the introduction of lyophilization process. Nevertheless, these products must be reconstituted using the diluent from a separate container before application. The possible solution for this problem is the application of dual chamber vials comprising the freeze-dried product in a lower compartment of the vial and the solution for reconstitution in the upper chamber. The main issue in development of such product is the choice of contact packaging (rubber closures, glass vials and the container closure system as a whole). The most important parameter used for evaluation of the influence of contact material on product quality was the pH value. The results have shown that the type of vials (moulded or tubular glass) has no impact on pH shift of the solution for reconstitution (tested solution-TS), while significant differences in pH value of the TS were observed depending on the rubber closures formulation used (with some formulations, the pH shift during the test was 6.5-9.14). Benzyl alcohol assay during the tests remained unchanged. Integrity tests of the container closure system (CCS) have demonstrated the adequacy of the selected packaging system. The quality of the CCS of choice was confirmed in the course of stability studies, only parameters directly influenced by CCS being presented in this work: loss on drying and pH value. On the basis of these results, no changes in loss on drying were connected to CCS, and the pH value of the reconstituted solution remains unchanged in samples tested both ex-tempore and after in-use period of 48 h.

Presence of Polycyclic Aromatic Hydrocarbons in Rubber Packaging Materials and in Parenteral Formulations Stored in Bottles With Rubber Stoppers.

PubMed

Bohrer, Denise; Viana, Carine; Barichello, Marcia M; de Moura, Juliane F; de Carvalho, Leandro M; Nascimento, Paulo C

2017-08-01

Rubber closures are the primary packaging material for sterile preparations intended for repeated use. Important features of rubber closures are achieved after additives are added to the elastomeric material that compounds the rubber. Among these additives is carbon black. Because of its origin, carbon black may contain polycyclic aromatic hydrocarbons (PAHs). The U.S. Environmental Protection Agency has identified 16 priority PAHs on the basis of concerns that they cause or might cause cancer in animals and humans. Regulatory agencies impose carbon black purity specifications based on limits for total PAHs (0.5 mg/kg) and benzo[a]pyrene (5 μg/kg) or benzo[a]pyrene only (250 μg/kg). PAHs in rubber packaging used for pharmaceutical formulations and in parenteral products stored in containers with rubber stoppers were investigated. To this end, the method proposed by the National Institute for Occupational Safety and Health-based on high-performance liquid chromatography with ultraviolet and fluorescence detection-was adapted to determine the levels of PAHs in rubber stoppers (gray and red) and in lipid emulsions and amino acid solutions stored in bottles with rubber stoppers. The rubber materials were shown to contain 12 PAHs, in concentrations ranging from 0.25-3.31 µg/g. Only 1 of 18 samples (11 amino acid solutions and 7 lipid emulsions) was uncontaminated. The most prevalent contaminants were pyrene, benzo[a]pyrene, and fluoranthene. The total PAH concentrations in the samples ranged from 0.11-5.96 µg/mL. Components of parenteral nutrition may be contaminated with PAHs, and rubber stoppers represent a potential source of these contaminants.

Closure development for high-level nuclear waste containers for the tuff repository; Phase 1, Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robitz, E.S. Jr.; McAninch, M.D. Jr.; Edmonds, D.P.

1990-09-01

This report summarizes Phase 1 activities for closure development of the high-level nuclear waste package task for the tuff repository. Work was conducted under U.S. Department of Energy (DOE) Contract 9172105, administered through the Lawrence Livermore National Laboratory (LLNL), as part of the Yucca Mountain Project (YMP), funded through the DOE Office of Civilian Radioactive Waste Management (OCRWM). The goal of this phase was to select five closure processes for further evaluation in later phases of the program. A decision tree methodology was utilized to perform an objective evaluation of 15 potential closure processes. Information was gathered via a literaturemore » survey, industrial contacts, and discussions with project team members, other experts in the field, and the LLNL waste package task staff. The five processes selected were friction welding, electron beam welding, laser beam welding, gas tungsten arc welding, and plasma arc welding. These are felt to represent the best combination of weldment material properties and process performance in a remote, radioactive environment. Conceptual designs have been generated for these processes to illustrate how they would be implemented in practice. Homopolar resistance welding was included in the Phase 1 analysis, and developments in this process will be monitored via literature in Phases 2 and 3. Work was conducted in accordance with the YMP Quality Assurance Program. 223 refs., 20 figs., 9 tabs.« less

Open abdomen treatment for septic patients with gastrointestinal fistula: from fistula control to definitive closure.

PubMed

Ren, Jianan; Yuan, Yujie; Zhao, Yunzhao; Gu, Guosheng; Wang, Gefei; Chen, Jun; Fan, Chaogang; Wang, Xinbo; Li, Jieshou

2014-04-01

The use of open abdomen in the management of gastrointestinal fistula complicated with severe intra-abdominal infection is uncommon. This study was designed to evaluate outcomes of our staged approach for the infected open abdomen. Patients who had gastrointestinal fistula and underwent open abdomen treatment were retrospectively reviewed. Various materials such as polypropylene mesh and a modified sandwich package were used to achieve temporary abdominal closure followed by skin grafting when the granulation bed matured. A delayed definitive operation was performed for final abdominal closure without implant of prosthetic mesh. Between 1999 and 2009, 56 (68.3%) of 82 patients survived through this treatment. Among them, 42 patients achieved final abdominal closure. Spontaneous fistula closure occurred in 16 patients with secondary fistula recorded in six patients. Besides, wound complications occurred in 13 patients with two cases for pulmonary infection. Within a 12-month follow-up period after definitive closure, no additional fistula was recorded excluding planned ventral hernia repair. Open abdomen treatment was effective for gastrointestinal fistula complicated by severe intra-abdominal infection. A delayed and deliberate operative strategy aiming at fistula excision and fascial closure, with simultaneous abdominal wall reconstruction, was required for the infected open abdomen.

WASTE PACKAGE REMEDIATION SYSTEM DESCRIPTION DOCUMENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

N.D. Sudan

2000-06-22

The Waste Package Remediation System remediates waste packages (WPs) and disposal containers (DCs) in one of two ways: preparation of rejected DC closure welds for repair or opening of the DC/WP. DCs are brought to the Waste Package Remediation System for preparation of rejected closure welds if testing of the closure weld by the Disposal Container Handling System indicates an unacceptable, but repairable, welding flaw. DC preparation of rejected closure welds will require removal of the weld in such a way that the Disposal Container Handling System may resume and complete the closure welding process. DCs/WPs are brought to themore » Waste Package Remediation System for opening if the Disposal Container Handling System testing of the DC closure weld indicates an unrepairable welding flaw, or if a WP is recovered from the subsurface repository because suspected damage to the WP or failure of the WP has occurred. DC/WP opening will require cutting of the DC/WP such that a temporary seal may be installed and the waste inside the DC/WP removed by another system. The system operates in a Waste Package Remediation System hot cell located in the Waste Handling Building that has direct access to the Disposal Container Handling System. One DC/WP at a time can be handled in the hot cell. The DC/WP arrives on a transfer cart, is positioned within the cell for system operations, and exits the cell without being removed from the cart. The system includes a wide variety of remotely operated components including a manipulator with hoist and/or jib crane, viewing systems, machine tools for opening WPs, and equipment used to perform pressure and gas composition sampling. Remotely operated equipment is designed to facilitate DC/WP decontamination and hot cell equipment maintenance, and interchangeable components are provided where appropriate. The Waste Package Remediation System interfaces with the Disposal Container Handling System for the receipt and transport of WPs and DCs. The Waste Handling Building System houses the system, and provides the facility, safety, and auxiliary systems required to support operations. The system receives power from the Waste Handling Building Electrical System. The system also interfaces with the various DC systems.« less

49 CFR 178.955 - General requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... void space(s) and to prevent significant movement of the inner packagings. (h) Proof of compliance. In... subchapter. Variations are permitted in inner packagings of a tested Large Packaging, without further testing... determine that the inner packaging, including closure, maintains an equivalent level of performance is...

49 CFR 178.955 - General requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... void space(s) and to prevent significant movement of the inner packagings. (h) Proof of compliance. In... subchapter. Variations are permitted in inner packagings of a tested Large Packaging, without further testing... determine that the inner packaging, including closure, maintains an equivalent level of performance is...

49 CFR 178.955 - General requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... void space(s) and to prevent significant movement of the inner packagings. (h) Proof of compliance. In... subchapter. Variations are permitted in inner packagings of a tested Large Packaging, without further testing... determine that the inner packaging, including closure, maintains an equivalent level of performance is...

49 CFR 178.955 - General requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... void space(s) and to prevent significant movement of the inner packagings. (h) Proof of compliance. In... subchapter. Variations are permitted in inner packagings of a tested Large Packaging, without further testing... determine that the inner packaging, including closure, maintains an equivalent level of performance is...

Determination of the Porosity Surfaces of the Disposal Room Containing Various Waste Inventories for WIPP PA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, Byoung Yoon; Hansen, Francis D.

2005-07-01

This report develops a series of porosity surfaces for the Waste Isolation Pilot Plant. The concept of a porosity surface was developed for performance assessment and comprises calculation of room closure as salt creep processes are mitigated by gas generation and back stress created by the waste packages within the rooms. The physical and mechanical characteristics of the waste packaging that has already been disposed--such as the pipe overpack--and new waste packaging--such as the advanced mixed waste compaction--are appreciably different than the waste form upon which the original compliance was based and approved. This report provides structural analyses of roommore » closure with various waste inventories. All of the underlying assumptions pertaining to the original compliance certification including the same finite element code are implemented; only the material parameters describing the more robust waste packages are changed from the certified baseline. As modeled, the more rigid waste tends to hold open the rooms and create relatively more void space in the underground than identical calculations run on the standard waste packages, which underpin the compliance certification. The several porosity surfaces quantified within this report provide possible ranges of pressure and porosity for performance assessment analyses.3 Intentionally blank4 AcknowledgementsThis research is funded by WIPP programs administered by the U.S. Department of Energy. The authors would like to acknowledge the valuable contributions to this work provided by others. Dr. Joshua S. Stein helped explain the hand off between these finite element porosity surfaces and implementation in the performance calculations. Dr. Leo L. Van Sambeek of RESPEC Inc. helped us understand the concepts of room closure under the circumstances created by a rigid waste inventory. Dr. T. William Thompson and Tom W. Pfeifle provided technical review and Mario J. Chavez provided a Quality Assurance review. The paper has been improved by these individuals.Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy under Contract DE-AC04-94Al850005 Intentionally Blank6« less

Assessment of Residual Stresses in 3013 Inner and Outer Containers and Teardrop Samples

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stroud, Mary Ann; Prime, Michael Bruce; Veirs, Douglas Kirk

2015-12-08

This report is an assessment performed by LANL that examines packaging for plutonium-bearing materials and the resilience of its design. This report discusses residual stresses in the 3013 outer, the SRS/Hanford and RFETS/LLNL inner containers, and teardrop samples used in studies to assess the potential for SCC in 3013 containers. Residual tensile stresses in the heat affected zones of the closure welds are of particular concern.

Packaging Considerations for Biopreservation

PubMed Central

Woods, Erik J.; Thirumala, Sreedhar

2011-01-01

Summary The packaging system chosen for biopreservation is critical for many reasons. An ideal biopreservation container system must provide for closure integrity, sample stability and ready access to the preserved material. This means the system needs to be hermetically sealed to ensure integrity of the specimen is maintained throughout processing, storage and distribution; the system must remain stable over long periods of time as many biobanked samples may be stored indefinitely; and functionally closed access systems must be used to avoid contamination upon sample withdraw. This study reviews the suitability of a new commercially available vial configuration container utilizing blood bag style closure and access systems that can be hermetically sealed and remain stable through cryopreservation and biobanking procedures. This vial based systems allow for current good manufacturing/tissue practice (cGTP) requirements during processing of samples and may provide the benefit of ease of delivery by a care giver. In this study, the CellSeal® closed system cryovial was evaluated and compared to standard screw cap vials. The CellSeal system was evaluated for durability, closure integrity through transportation and maintenance of functional viability of a cryopreserved mesenchymal stem cell model. The results of this initial proof-of-concept study indicated that the CellSeal vials are highly suitable for biopreservation and biobanking, and provide a suitable container system for clinical and commercial cell therapy products frozen in small volumes. PMID:21566715

49 CFR 173.167 - Consumer commodities.

Code of Federal Regulations, 2013 CFR

2013-10-01

... exceed 30 kg (66 pounds) gross weight as prepared for shipment. (2) Closures. Friction-type closures must...) prescribed in § 173.27(c) of this part. The capability of a packaging to withstand an internal pressure...

21 CFR 178.3290 - Chromic chloride complexes.

Code of Federal Regulations, 2014 CFR

2014-04-01

... square inch of closure area. (b) The packaging container which has its closure area treated with the release agent shall have a capacity of not less than 120 grams of food per square inch of such treated...

Microbial barrier assessment of Tyvek stopper packaging for rubber closures.

PubMed

Moldenhauer, J E; Bass, S A; Kupinski, M J; Walters, M L; Rubio, S L

1996-01-01

Two types of Tyvek and high density polyethylene or polypropylene packaging used for sterilization of rubber closures were evaluated for Microbial Barrier properties. The packaging evaluated was "Ready to Sterilize" (1) stoppers and a second test package (Test 2) which was designated as appropriate for a clean room, filled with washed and siliconized stoppers and then heat sealed. Each type of packaging was subjected to three different sterilization temperatures (125 degrees C, 128 degrees C and 131 degrees C) in a production sterilizer (15-18 psi). Following sterilization, a microbial barrier assessment was performed, using Bacillus subtilis niger (ATCC 9372), to determine whether the packaging could maintain a sterile barrier following sterilization. Results of the testing indicated that a microbial barrier was maintained for products in "Ready to Sterilize" packages at 125 degrees C and 128 degrees C. For products sterilized in the Test 2 container a microbial barrier could not be maintained at 128 degrees C, and no further testing was performed. Following sterilization at 131 degrees C physical defects were noted for the "Ready to Sterilize" bag and a microbial barrier could not be maintained.

Temperature-package power correlations for open-mode geologic disposal concepts.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hardin, Ernest.

2013-02-01

Logistical simulation of spent nuclear fuel (SNF) management in the U.S. combines storage, transportation and disposal elements to evaluate schedule, cost and other resources needed for all major operations leading to final geologic disposal. Geologic repository reference options are associated with limits on waste package thermal power output at emplacement, in order to meet limits on peak temperature for certain key engineered and natural barriers. These package power limits are used in logistical simulation software such as CALVIN, as threshold requirements that must be met by means of decay storage or SNF blending in waste packages, before emplacement in amore » repository. Geologic repository reference options include enclosed modes developed for crystalline rock, clay or shale, and salt. In addition, a further need has been addressed for open modes in which SNF can be emplaced in a repository, then ventilated for decades or longer to remove heat, prior to permanent repository closure. For each open mode disposal concept there are specified durations for surface decay storage (prior to emplacement), repository ventilation, and repository closure operations. This study simulates those steps for several timing cases, and for SNF with three fuel-burnup characteristics, to develop package power limits at which waste packages can be emplaced without exceeding specified temperature limits many years later after permanent closure. The results are presented in the form of correlations that span a range of package power and peak postclosure temperature, for each open-mode disposal concept, and for each timing case. Given a particular temperature limit value, the corresponding package power limit for each case can be selected for use in CALVIN and similar tools.« less

21 CFR 212.40 - How must I control the components I use to produce PET drugs and the containers and closures I...

Code of Federal Regulations, 2014 CFR

2014-04-01

... PET drugs and the containers and closures I package them in? 212.40 Section 212.40 Food and Drugs FOOD..., and Closures § 212.40 How must I control the components I use to produce PET drugs and the containers... not use in PET drug production any lot that does not meet its specifications, including any expiration...

21 CFR 212.40 - How must I control the components I use to produce PET drugs and the containers and closures I...

Code of Federal Regulations, 2013 CFR

2013-04-01

... PET drugs and the containers and closures I package them in? 212.40 Section 212.40 Food and Drugs FOOD..., and Closures § 212.40 How must I control the components I use to produce PET drugs and the containers... not use in PET drug production any lot that does not meet its specifications, including any expiration...

21 CFR 212.40 - How must I control the components I use to produce PET drugs and the containers and closures I...

Code of Federal Regulations, 2012 CFR

2012-04-01

... PET drugs and the containers and closures I package them in? 212.40 Section 212.40 Food and Drugs FOOD..., and Closures § 212.40 How must I control the components I use to produce PET drugs and the containers... not use in PET drug production any lot that does not meet its specifications, including any expiration...

21 CFR 212.40 - How must I control the components I use to produce PET drugs and the containers and closures I...

Code of Federal Regulations, 2011 CFR

2011-04-01

... PET drugs and the containers and closures I package them in? 212.40 Section 212.40 Food and Drugs FOOD..., and Closures § 212.40 How must I control the components I use to produce PET drugs and the containers... not use in PET drug production any lot that does not meet its specifications, including any expiration...

Sealing Mustard Jars with Plastic Linerless Closures

DTIC Science & Technology

1985-10-01

Recommendations 15 Literature cited 16 Appendices: A . Levels of Packaging 19 B. Value Engineering Correspondence 2 3 V ILLUSTRATIVE DATA Page...Analytical Progress Total Dietary Fiber Another Look, 1984, Vol 2,■No. 1, Minneapolis, MN 16 APPENDIXES A : Levels of Packaging B: Value...Engineering Correspondence 17 APPENDIX A : Levels of Packaging 19 APPENDIX A : Levels of Packaging Excerpt from: AR 700-15/NAVSUPINST 4030.28B/AFR 71~6

MEANS: python package for Moment Expansion Approximation, iNference and Simulation

PubMed Central

Fan, Sisi; Geissmann, Quentin; Lakatos, Eszter; Lukauskas, Saulius; Ale, Angelique; Babtie, Ann C.; Kirk, Paul D. W.; Stumpf, Michael P. H.

2016-01-01

Motivation: Many biochemical systems require stochastic descriptions. Unfortunately these can only be solved for the simplest cases and their direct simulation can become prohibitively expensive, precluding thorough analysis. As an alternative, moment closure approximation methods generate equations for the time-evolution of the system’s moments and apply a closure ansatz to obtain a closed set of differential equations; that can become the basis for the deterministic analysis of the moments of the outputs of stochastic systems. Results: We present a free, user-friendly tool implementing an efficient moment expansion approximation with parametric closures that integrates well with the IPython interactive environment. Our package enables the analysis of complex stochastic systems without any constraints on the number of species and moments studied and the type of rate laws in the system. In addition to the approximation method our package provides numerous tools to help non-expert users in stochastic analysis. Availability and implementation: https://github.com/theosysbio/means Contacts: m.stumpf@imperial.ac.uk or e.lakatos13@imperial.ac.uk Supplementary information: Supplementary data are available at Bioinformatics online. PMID:27153663

MEANS: python package for Moment Expansion Approximation, iNference and Simulation.

PubMed

Fan, Sisi; Geissmann, Quentin; Lakatos, Eszter; Lukauskas, Saulius; Ale, Angelique; Babtie, Ann C; Kirk, Paul D W; Stumpf, Michael P H

2016-09-15

Many biochemical systems require stochastic descriptions. Unfortunately these can only be solved for the simplest cases and their direct simulation can become prohibitively expensive, precluding thorough analysis. As an alternative, moment closure approximation methods generate equations for the time-evolution of the system's moments and apply a closure ansatz to obtain a closed set of differential equations; that can become the basis for the deterministic analysis of the moments of the outputs of stochastic systems. We present a free, user-friendly tool implementing an efficient moment expansion approximation with parametric closures that integrates well with the IPython interactive environment. Our package enables the analysis of complex stochastic systems without any constraints on the number of species and moments studied and the type of rate laws in the system. In addition to the approximation method our package provides numerous tools to help non-expert users in stochastic analysis. https://github.com/theosysbio/means m.stumpf@imperial.ac.uk or e.lakatos13@imperial.ac.uk Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.

49 CFR 178.960 - Preparation of Large Packagings for testing.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., including inner packagings. All closures must be installed using proper techniques and torques. (b) For the...). Average values should fall within these limits. Short-term fluctuations and measurement limitations may cause individual measurements to vary by up to ± 5 percent relative humidity without significant...

49 CFR 178.960 - Preparation of Large Packagings for testing.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., including inner packagings. All closures must be installed using proper techniques and torques. (b) For the...). Average values should fall within these limits. Short-term fluctuations and measurement limitations may cause individual measurements to vary by up to ± 5 percent relative humidity without significant...

49 CFR 178.960 - Preparation of Large Packagings for testing.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., including inner packagings. All closures must be installed using proper techniques and torques. (b) For the...). Average values should fall within these limits. Short-term fluctuations and measurement limitations may cause individual measurements to vary by up to ±5 percent relative humidity without significant...

49 CFR 178.960 - Preparation of Large Packagings for testing.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., including inner packagings. All closures must be installed using proper techniques and torques. (b) For the...). Average values should fall within these limits. Short-term fluctuations and measurement limitations may cause individual measurements to vary by up to ±5 percent relative humidity without significant...

49 CFR 178.960 - Preparation of Large Packagings for testing.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., including inner packagings. All closures must be installed using proper techniques and torques. (b) For the...). Average values should fall within these limits. Short-term fluctuations and measurement limitations may cause individual measurements to vary by up to ±5 percent relative humidity without significant...

High-Voltage Leak Detection of a Parenteral Proteinaceous Solution Product Packaged in Form-Fill-Seal Plastic Laminate Bags. Part 3. Chemical Stability and Visual Appearance of a Protein-Based Aqueous Solution for Injection as a Function of HVLD Exposure.

PubMed

Rasmussen, Mats; Damgaard, Rasmus; Buus, Peter; Guazzo, Dana Morton

2013-01-01

This Part 3 of this three-part research series reports the impact of high-voltage leak detection (HVLD) exposure on the physico-chemical stability of the packaged product. The product, intended for human administration by injection, is an aqueous solution formulation of the rapid acting insulin analogue, insulin aspart (NovoRapid®/NovoLog®) by Novo Nordisk A/S, Bagsværd, Denmark. The package is a small-volume form-fill-seal plastic laminate bag. Product-packages exposed to HVLD were compared to unexposed product after storage for 9 months at recommended storage conditions of 5 ± 3 °C. No differences in active ingredient or degradation products assays were noted. No changes in any other stability indicating parameter results were observed. This report concludes this three-part series. Part 1 documented HVLD method development and validation work. Part 2 explored the impact of various package material, package temperature, and package storage conditions on HVLD test results. Detection of leaks in the bag seal area was investigated. In conclusion, HVLD is reported to be a validatable leak test method suitable for rapid, nondestructive container-closure integrity evaluation of the subject product-package. In Part 1 of this three-part series, a leak test method based on electrical conductivity and capacitance, also called high-voltage leak detection (HVLD), was proven to find hole leaks in small plastic bags filled with a solution of insulin aspart intended for human injection (NovoRapid®/NovoLog® by Novo Nordisk A/S, Bagsværd, Denmark). In Part 2, the ability of the HVLD method to find other types of package leaks was tested, and the impact of package material and product storage temperature on HVLD results was explored. This final Part 3 checked how well the packaged protein drug solution maintained its potency after HVLD exposure over 9 months of storage under long-term stability conditions. Results showed that HVLD caused no harm to the product.

Effects of Laser Etching on the Corrosion Susceptibility of SAVY 4000 and Hagan Containers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hyer, Holden Christopher; Duque, Juan; Smith, Paul Herrick

Since the late 1990’s, the Hagan container was used as the primary container for packaging of plutonium-bearing materials. The Hagan design consisted of a threaded closure, a Viton® ORing, a carbon-carbon filter, and a 304L stainless steel (SS) body. Over the years, Hagans have shown vulnerability in their design [1]. In 2008, The Department of Energy (DOE) issued DOE M 441.1-1, Nuclear Material Packaging Manual, which detailed an approach to obtain highconfidence in containers by including specific design requirements, material contents and an approach to determine life span from said contents, and surveillance techniques [2]. In response to both themore » vulnerability issues with the Hagan and DOE M 441.1-1, the SAVY 4000 container with its twist style closure, Viton® O-Ring, Fiberfrax-Gortex filter, and annealed 316L SS body, was designed as the replacement for Hagan containers, but only for a short term lifespan of 5 years [1]. However, both the Hagan and SAVY 4000 are being pushed to maintain a lifespan of 40 years. Therefore, proper confidence must be placed on each component of each container to last a minimum of 40 years. So far, the biggest concern found during surveillance of these containers is corrosion and the potential for failure by corrosion. One concern is that the containers fail due to stress corrosion cracking (SCC), especially around the weld between the collar and the body as welds leave residual stresses. One advantage the SAVY 4000 has is that the body is annealed, but its weld is still susceptible as it was welded after annealing [3, 4]. Moreover, 316L SS is known to have a higher pitting resistance (pits are a precursor to SCC and can also lead to extensive failure of the material), than 304L SS [4]. During recent surveillance activities, two SAVY 4000’s containing Solution Assay Instrument (SAI) solutions were opened. The SAI SAVY 4000’s contained plutonium (Pu) in 3M HCl solution in plastic volumetric flasks placed inside of polyethylene bags. Historically, a SAVY 4000 containing an SAI solution is packaged for 3 weeks, however, these particular containers were not reopened until 14 months later. When opened, brown-red corrosion product was found all over the inside of the container as shown in Figure 1.« less

Food packing optimization

NASA Technical Reports Server (NTRS)

1981-01-01

The development of a universal closure lid for the space shuttle food package is reported. The revised lid needs a folded configuration which, when unfolded, fully conforms to the interior surfaces of the food cup. Experimental thermoform molds were fabricated and test lids formed. The lid material not in contact with the food conformed to the cup interior without wrinkles, permitting full nesting of the cups. The final lid design was established and thermoform tooling designed and fabricated. Lids formed on these molds were tested for strength. The heating elements were replaced and repositioned to eliminate any hot spots which may cause warpage.

Chromatographic and Spectral Analysis of Two Main Extractable Compounds Present in Aqueous Extracts of Laminated Aluminum Foil Used for Protecting LDPE-Filled Drug Vials

PubMed Central

Akapo, Samuel O.; Syed, Sajid; Mamangun, Anicia; Skinner, Wayne

2009-01-01

Laminated aluminum foils are increasingly being used to protect drug products packaged in semipermeable containers (e.g., low-density polyethylene (LDPE)) from degradation and/or evaporation. The direct contact of such materials with primary packaging containers may potentially lead to adulteration of the drug product by extractable or leachable compounds present in the closure system. In this paper, we described a simple and reliable HPLC method for analysis of an aqueous extract of laminated aluminum foil overwrap used for packaging LDPE vials filled with aqueous pharmaceutical formulations. By means of combined HPLC-UV, GC/MS, LC/MS/MS, and NMR spectroscopy, the two major compounds detected in the aqueous extracts of the representative commercial overwraps were identified as cyclic oligomers with molecular weights of 452 and 472 and are possibly formed from poly-condensation of the adhesive components, namely, isophthalic acid, adipic acid, and diethylene glycol. Lower molecular weight compounds that might be associated with the “building blocks” of these compounds were not detected in the aqueous extracts. PMID:20140083

Peering down the barrel of a bacteriophage portal: the genome packaging and release valve in p22.

PubMed

Tang, Jinghua; Lander, Gabriel C; Olia, Adam S; Olia, Adam; Li, Rui; Casjens, Sherwood; Prevelige, Peter; Cingolani, Gino; Baker, Timothy S; Johnson, John E

2011-04-13

The encapsidated genome in all double-strand DNA bacteriophages is packaged to liquid crystalline density through a unique vertex in the procapsid assembly intermediate, which has a portal protein dodecamer in place of five coat protein subunits. The portal orchestrates DNA packaging and exit, through a series of varying interactions with the scaffolding, terminase, and closure proteins. Here, we report an asymmetric cryoEM reconstruction of the entire P22 virion at 7.8 Å resolution. X-ray crystal structure models of the full-length portal and of the portal lacking 123 residues at the C terminus in complex with gene product 4 (Δ123portal-gp4) obtained by Olia et al. (2011) were fitted into this reconstruction. The interpreted density map revealed that the 150 Å, coiled-coil, barrel portion of the portal entraps the last DNA to be packaged and suggests a mechanism for head-full DNA signaling and transient stabilization of the genome during addition of closure proteins. Copyright © 2011 Elsevier Ltd. All rights reserved.

Method Development for Container Closure Integrity Evaluation via Headspace Gas Ingress by Using Frequency Modulation Spectroscopy.

PubMed

Victor, Ken G; Levac, Lauren; Timmins, Michael; Veale, James

2017-01-01

USP <1207.1> Section 3.5 states that "A deterministic leak test method having the ability to detect leaks at the product's maximum allowable leakage limit is preferred when establishing the inherent integrity of a container-closure system." Ideally, container closure integrity of parenteral packaging would be evaluated by measuring a physical property that is sensitive to the presence of any package defect that breaches package integrity by increasing its leakage above its maximum allowable leakage limit. The primary goals of the work presented herein were to demonstrate the viability of the nondestructive, deterministic method known as laser-based gas headspace analysis for evaluating container closure integrity and to provide a physical model for predicting leak rates for a variety of container volumes, headspace conditions, and defect sizes. The results demonstrate that laser-based headspace analysis provides sensitive, accurate, and reproducible measurements of the gas ingress into glass vial-stopper package assemblies that are under either diffusive or effusive leak conditions. Two different types of positive controls were examined. First, laser-drilled micro-holes in thin metal disks that were crimped on top of 15R glass vials served as positive controls with a well-characterized defect geometry. For these, a strong correlation was observed between the measured ingress parameter and the size of the defect for both diffusive and effusive conditions. Second, laser-drilled holes in the wall of glass vials served as controls that more closely simulate real-world defects. Due to their complex defect geometries, their diffusive and effusive ingress parameters did not necessarily correlate; this is an important observation that has significant implications for standardizing the characterization of container defects. Regardless, laser-based headspace analysis could readily differentiate positive and negative controls for all leak conditions, and the results provide a guide for method development of container closure integrity tests. LAY ABSTRACT: The new USP 39 <1207>, "Package Integrity Evaluation-Sterile Products", states in section 3.4.1: "tracer gas tests performed using … laser-based gas headspace analysis [have] been shown to be sensitive enough to quantitatively analyze leakage through the smallest leak paths found to pose the smallest chance of liquid leakage or microbial ingress in rigid packaging." In addition, USP <1207> also states that "for such methods, the limit of detection can be mathematically predicted on the basis of gas flow kinetics." Using the above statements as a foundation, this paper presents a theoretical basis for predicting the gas ingress through well-defined defects in product vials sealed under a variety of headspace conditions. These calculated predictions were experimentally validated by comparing them to measurements of changes in the headspace oxygen content or total pressure for several different positive controls using laser-based headspace analysis. The results demonstrated that laser-based headspace analysis can, by readily differentiating between negative controls and positive controls with a range of defect sizes on the micron scale, be used to assess container closure integrity. The work also demontrated that caution must be used when attempting to correlate a leak rate to an idealized defect-size parameter. © PDA, Inc. 2017.

Rock mechanics evaluation of potential repository sites in the Paradox, Permian, and Gulf Coast Basins: Volume 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1987-09-01

Thermal and thermomechanical analyses of a conceptual radioactive waste repository containing commercial and defense high-level wastes and spent fuel have been performing using finite element models. The thermal and thermomechanical responses of the waste package, disposal room, and repository regions were evaluated. four bedded salt formations, in Davis and Lavender Canyons in the Paradox Basin of southeastern Utah and in Deaf Smith and Swisher counties in the Permian Basin of northwestern Texas, and three salt domes, Vacherie Dome in northwestern Louisiana and Richton and Cypress Creek Domes in southeastern Mississippi, located in the Gulf Coast Basin, were examined. In themore » Paradox Basin, the pressure exerted on the waste package overpack was much greater than the initial in situ stress. The disposal room closure was less than 10 percent after 5 years. Surface uplift was nominal, and no significant thermomechanical perturbation of the aquitards was observed. In the Permian Basin, the pressure exerted on the waste package overpack was greater than the initial in situ stress. The disposal room closures were greater than 10 percent in less than 5 years. Surface uplift was nominal, and no significant thermomechanical perturbation of the aquitards was observed. In the Gulf Coast Basin, the pressure exerted on the waste package overpack was greater than the initial in situ stress. The disposal room closures were greater than 10 percent in less than 5 years. No significant thermomechanical perturbation of the overlying geology was observed. 40 refs., 153 figs., 32 tabs.« less

Cutaneous Wound Closure Materials: An Overview and Update

PubMed Central

Al-Mubarak, Luluah; Al-Haddab, Mohammed

2013-01-01

Introduction: On a daily basis, dermasurgeons are faced with different kinds of wounds that have to be closed. With a plethora of skin closure materials currently available, choosing a solution that combines excellent and rapid cosmetic results with practicality and cost-effectiveness can be difficult, if not tricky. Objectives: We aimed to review the available skin closure materials over the past 20 years and the scientific claims behind their effectiveness in repairing various kinds of wounds. Materials and Methods: The two authors independently searched and scrutinised the literature. The search was performed electronically using Pub Med, the Cochrane Database, Google Scholar and Ovid as search engines to find articles concerning skin closure materials written since 1990. Conclusion: Many factors are involved in the choice of skin closure material, including the type and place of the wound, available materials, physician expertise and preferences, and patient age and health. Evidence-based main uses of different skin closure materials are provided to help surgeons choose the appropriate material for different wounds. PMID:24470712

21 CFR 212.40 - How must I control the components I use to produce PET drugs and the containers and closures I...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 4 2010-04-01 2010-04-01 false How must I control the components I use to produce PET drugs and the containers and closures I package them in? 212.40 Section 212.40 Food and Drugs FOOD... GOOD MANUFACTURING PRACTICE FOR POSITRON EMISSION TOMOGRAPHY DRUGS (Eff. 12-12-2011) Control of...

Contamination of injectable solutions with 2-mercaptobenzothiazole leached from rubber closures.

PubMed

Reepmeyer, J C; Juhl, Y H

1983-11-01

An impurity, discovered in a sample of digoxin injectable solution commercially packaged in a syringe for single-dose delivery, was found to originate from the rubber closure of the syringe and was identified as 2-mercaptobenzothiazole, a common accelerator for rubber vulcanization. Several similarly packaged injectable solutions of a variety of drugs from various manufacturers were examined and over half contained 2-mercaptobenzothiazole. The compound was identified by UV spectrophotometry (including a pH-dependent shift in its absorbance maximum), by mass spectrometry, and by comparison with standard 2-mercaptobenzothiazole using silica gel and reverse-phase high-performance liquid chromatography (HPLC). The presence of this impurity in injectable solutions may have implications with regard to toxicity and may interfere with the assay of digoxin injectable solution by HPLC.

Space Station evolution study oxygen loop closure

NASA Technical Reports Server (NTRS)

Wood, M. G.; Delong, D.

1993-01-01

In the current Space Station Freedom (SSF) Permanently Manned Configuration (PMC), physical scars for closing the oxygen loop by the addition of oxygen generation and carbon dioxide reduction hardware are not included. During station restructuring, the capability for oxygen loop closure was deferred to the B-modules. As such, the ability to close the oxygen loop in the U.S. Laboratory module (LAB A) and the Habitation A module (HAB A) is contingent on the presence of the B modules. To base oxygen loop closure of SSF on the funding of the B-modules may not be desirable. Therefore, this study was requested to evaluate the necessary hooks and scars in the A-modules to facilitate closure of the oxygen loop at or subsequent to PMC. The study defines the scars for oxygen loop closure with impacts to cost, weight and volume and assesses the effects of byproduct venting. In addition, the recommended scenarios for closure with regard to topology and packaging are presented.

BRAC, What Will it Cost

DTIC Science & Technology

1992-04-10

Devens - Fort Huachuca FY 91 FY 95 Fort McClellan FY 92 FY 96 Fort Chaffee FY 92 FY 97 Cameron Station FY 91 FY 95 53 Stand Alone Housing Sites FY 90 FY...Army, Headquarters Forces Command, &as Realianment and Closure Implementation Plan - Fort Devens Closure Package, Implementation Plan, Fort McPherson, GA...Classification) RAC , What Will It Cost? 12. PERSONAL AUTHOR(S) TLIN, Robert B. LTC, USA 13. TYPE OF REPORT 13b. TIME COVERED 14. DATE OF REPORT (Year

40 CFR 264.228 - Closure and post-closure care.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Closure and post-closure care. 264.228... Surface Impoundments § 264.228 Closure and post-closure care. (a) At closure, the owner or operator must... materials are left in place at final closure, the owner or operator must comply with all post-closure...

40 CFR 264.228 - Closure and post-closure care.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Closure and post-closure care. 264.228... Surface Impoundments § 264.228 Closure and post-closure care. (a) At closure, the owner or operator must... materials are left in place at final closure, the owner or operator must comply with all post-closure...

40 CFR 264.228 - Closure and post-closure care.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Closure and post-closure care. 264.228... Surface Impoundments § 264.228 Closure and post-closure care. (a) At closure, the owner or operator must... materials are left in place at final closure, the owner or operator must comply with all post-closure...

40 CFR 264.228 - Closure and post-closure care.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Closure and post-closure care. 264.228... Surface Impoundments § 264.228 Closure and post-closure care. (a) At closure, the owner or operator must... materials are left in place at final closure, the owner or operator must comply with all post-closure...

40 CFR 264.228 - Closure and post-closure care.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Closure and post-closure care. 264.228... Surface Impoundments § 264.228 Closure and post-closure care. (a) At closure, the owner or operator must... materials are left in place at final closure, the owner or operator must comply with all post-closure...

Closure Plan for the Area 5 Radioactive Waste Management Site at the Nevada Test Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

NSTec Environmental Management

The Area 5 Radioactive Waste Management Site (RMWS) at the Nevada Test Site (NTS) is managed and operated by National Security Technologies, LLC (NSTec), for the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO). This document is the first update of the preliminary closure plan for the Area 5 RWMS at the NTS that was presented in the Integrated Closure and Monitoring Plan (DOE, 2005a). The major updates to the plan include a new closure schedule, updated closure inventory, updated site and facility characterization data, the Title II engineering cover design, and the closure processmore » for the 92-Acre Area of the RWMS. The format and content of this site-specific plan follows the Format and Content Guide for U.S. Department of Energy Low-Level Waste Disposal Facility Closure Plans (DOE, 1999a). This interim closure plan meets closure and post-closure monitoring requirements of the order DOE O 435.1, manual DOE M 435.1-1, Title 40 Code of Federal Regulations (CFR) Part 191, 40 CFR 265, Nevada Administrative Code (NAC) 444.743, and Resource Conservation and Recovery Act (RCRA) requirements as incorporated into NAC 444.8632. The Area 5 RWMS accepts primarily packaged low-level waste (LLW), low-level mixed waste (LLMW), and asbestiform low-level waste (ALLW) for disposal in excavated disposal cells.« less

Final closure of a low level waste disposal facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Potier, J.M.

1995-12-31

The low-level radioactive waste disposal facility operated by the Agence Nationale pour la Gestion des Dechets Radioactifs near La Hague, France was opened in 1969 and is scheduled for final closure in 1996. The last waste package was received in June 1994. The total volume of disposed waste is approximately 525,000 m{sup 3}. The site closure consists of covering the disposal structures with a multi-layer impervious cap system to prevent rainwater from infiltrating the waste isolation system. A monitoring system has been set up to verify the compliance of infiltration rates with hydraulic performance objectives (less than 10 liters permore » square meter and per year).« less

21 CFR 211.42 - Design and construction features.

Code of Federal Regulations, 2014 CFR

2014-04-01

... product containers, closures, labeling, in-process materials, or drug products, and to prevent contamination. The flow of components, drug product containers, closures, labeling, in-process materials, and... withholding from use of components, drug product containers, closures, and labeling, pending the appropriate...

21 CFR 211.42 - Design and construction features.

Code of Federal Regulations, 2012 CFR

2012-04-01

... product containers, closures, labeling, in-process materials, or drug products, and to prevent contamination. The flow of components, drug product containers, closures, labeling, in-process materials, and... withholding from use of components, drug product containers, closures, and labeling, pending the appropriate...

21 CFR 211.42 - Design and construction features.

Code of Federal Regulations, 2013 CFR

2013-04-01

... product containers, closures, labeling, in-process materials, or drug products, and to prevent contamination. The flow of components, drug product containers, closures, labeling, in-process materials, and... withholding from use of components, drug product containers, closures, and labeling, pending the appropriate...

21 CFR 211.42 - Design and construction features.

Code of Federal Regulations, 2011 CFR

2011-04-01

... product containers, closures, labeling, in-process materials, or drug products, and to prevent contamination. The flow of components, drug product containers, closures, labeling, in-process materials, and... withholding from use of components, drug product containers, closures, and labeling, pending the appropriate...

Nickel-Titanium Wire as Suture Material: A New Technique for the Fixation of Skin.

PubMed

Li, Haidong; Song, Tao

2018-01-29

To introduce nickel-titanium wire as suture material for closure of incisions in cleft lip procedures. Closure of skin incisions using nickel-titanium wire as suture material, with postoperative follow-up wound evaluation. There was excellent patient satisfaction and good cosmetic outcome. Nickel-titanium wire is an excellent alternative for suture closure of cleft lip surgical incisions.

49 CFR 173.188 - White or yellow phosphorus.

Code of Federal Regulations, 2013 CFR

2013-10-01

...) Inner water-tight metal cans containing not over 0.5 kg (1 pound) of phosphorus with screw-top closures... each. (b) When dry, it must be cast solid and shipped in packagings as follows: (1) Steel, aluminum or...

49 CFR 173.188 - White or yellow phosphorus.

Code of Federal Regulations, 2014 CFR

2014-10-01

...) Inner water-tight metal cans containing not over 0.5 kg (1 pound) of phosphorus with screw-top closures... each. (b) When dry, it must be cast solid and shipped in packagings as follows: (1) Steel, aluminum or...

Self-closing shielded container for use with radioactive materials

DOEpatents

Smith, Jay E.

1984-01-01

A container for storage of radioactive material comprising a container body nd a closure member. The closure member being coupled to the container body to enable the closure body to move automatically from a first position (e.g., closed) to a second position (open).

Self-closing shielded container for use with radioactive materials

DOEpatents

Smith, J.E.

A container for storage of radioactive material comprises a container body and a closure member. The closure member is coupled to the container body to enable the closure body to move automatically from a first position (e.g., closed) to a second position (open).

Vacuum decay container/closure integrity testing technology. Part 2. Comparison to dye ingress tests.

PubMed

Wolf, Heinz; Stauffer, Tony; Chen, Shu-Chen Y; Lee, Yoojin; Forster, Ronald; Ludzinski, Miron; Kamat, Madhav; Mulhall, Brian; Guazzo, Dana Morton

2009-01-01

Part 1 of this series demonstrated that a container closure integrity test performed according to ASTM F2338-09 Standard Test Method for Nondestructive Detection of Leaks in Packages by Vacuum Decay Method using a VeriPac 325/LV vacuum decay leak tester by Packaging Technologies & Inspection, LLC (PTI) is capable of detecting leaks > or = 5.0 microm (nominal diameter) in rigid, nonporous package systems, such as prefilled glass syringes. The current study compared USP, Ph.Eur. and ISO dye ingress integrity test methods to PTI's vacuum decay technology for the detection of these same 5-, 10-, and 15-microm laser-drilled hole defects in 1-mL glass prefilled syringes. The study was performed at three test sites using several inspectors and a variety of inspection conditions. No standard dye ingress method was found to reliably identify all holed syringes. Modifications to these standard dye tests' challenge conditions increased the potential for dye ingress, and adjustments to the visual inspection environment improved dye ingress detection. However, the risk of false positive test results with dye ingress tests remained. In contrast, the nondestructive vacuum decay leak test method reliably identified syringes with holes > or = 5.0 microm.

Vacuum decay container closure integrity leak test method development and validation for a lyophilized product-package system.

PubMed

Patel, Jayshree; Mulhall, Brian; Wolf, Heinz; Klohr, Steven; Guazzo, Dana Morton

2011-01-01

A leak test performed according to ASTM F2338-09 Standard Test Method for Nondestructive Detection of Leaks in Packages by Vacuum Decay Method was developed and validated for container-closure integrity verification of a lyophilized product in a parenteral vial package system. This nondestructive leak test method is intended for use in manufacturing as an in-process package integrity check, and for testing product stored on stability in lieu of sterility tests. Method development and optimization challenge studies incorporated artificially defective packages representing a range of glass vial wall and sealing surface defects, as well as various elastomeric stopper defects. Method validation required 3 days of random-order replicate testing of a test sample population of negative-control, no-defect packages and positive-control, with-defect packages. Positive-control packages were prepared using vials each with a single hole laser-drilled through the glass vial wall. Hole creation and hole size certification was performed by Lenox Laser. Validation study results successfully demonstrated the vacuum decay leak test method's ability to accurately and reliably detect those packages with laser-drilled holes greater than or equal to approximately 5 μm in nominal diameter. All development and validation studies were performed at Whitehouse Analytical Laboratories in Whitehouse, NJ, under the direction of consultant Dana Guazzo of RxPax, LLC, using a VeriPac 455 Micro Leak Test System by Packaging Technologies & Inspection (Tuckahoe, NY). Bristol Myers Squibb (New Brunswick, NJ) fully subsidized all work. A leak test performed according to ASTM F2338-09 Standard Test Method for Nondestructive Detection of Leaks in Packages by Vacuum Decay Method was developed and validated to detect defects in stoppered vial packages containing lyophilized product for injection. This nondestructive leak test method is intended for use in manufacturing as an in-process package integrity check, and for testing product stored on stability in lieu of sterility tests. Test method validation study results proved the method capable of detecting holes laser-drilled through the glass vial wall greater than or equal to 5 μm in nominal diameter. Total test time is less than 1 min per package. All method development and validation studies were performed at Whitehouse Analytical Laboratories in Whitehouse, NJ, under the direction of consultant Dana Guazzo of RxPax, LLC, using a VeriPac 455 Micro Leak Test System by Packaging Technologies & Inspection (Tuckahoe, NY). Bristol Myers Squibb (New Brunswick, NJ) fully subsidized all work.

Self-closing shielded container for use with radioactive materials

DOEpatents

Smith, J.E.

1984-10-16

A container is described for storage of radioactive material comprising a container body and a closure member. The closure member being coupled to the container body to enable the closure body to move automatically from a first position (e.g., closed) to a second position (open). 1 fig.

49 CFR 173.188 - White or yellow phosphorus.

Code of Federal Regulations, 2012 CFR

2012-10-01

... pound) of phosphorus with screw-top closures; or (2) Steel drums (1A1) not over 250 L (66 gallons... solid and shipped in packagings as follows: (1) Steel drums (1A2) not over 115 L (30 gallons) capacity...

49 CFR 173.459 - Mixing of fissile material packages with non-fissile or fissile-excepted material packages.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 2 2012-10-01 2012-10-01 false Mixing of fissile material packages with non... (Radioactive) Materials § 173.459 Mixing of fissile material packages with non-fissile or fissile-excepted material packages. Mixing of fissile material packages with other types of Class 7 (radioactive) materials...

49 CFR 173.459 - Mixing of fissile material packages with non-fissile or fissile-excepted material packages.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 2 2013-10-01 2013-10-01 false Mixing of fissile material packages with non... (Radioactive) Materials § 173.459 Mixing of fissile material packages with non-fissile or fissile-excepted material packages. Mixing of fissile material packages with other types of Class 7 (radioactive) materials...

49 CFR 173.459 - Mixing of fissile material packages with non-fissile or fissile-excepted material packages.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 2 2011-10-01 2011-10-01 false Mixing of fissile material packages with non... (Radioactive) Materials § 173.459 Mixing of fissile material packages with non-fissile or fissile-excepted material packages. Mixing of fissile material packages with other types of Class 7 (radioactive) materials...

49 CFR 173.459 - Mixing of fissile material packages with non-fissile or fissile-excepted material packages.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Mixing of fissile material packages with non... (Radioactive) Materials § 173.459 Mixing of fissile material packages with non-fissile or fissile-excepted material packages. Mixing of fissile material packages with other types of Class 7 (radioactive) materials...

49 CFR 173.459 - Mixing of fissile material packages with non-fissile or fissile-excepted material packages.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 2 2014-10-01 2014-10-01 false Mixing of fissile material packages with non... (Radioactive) Materials § 173.459 Mixing of fissile material packages with non-fissile or fissile-excepted material packages. Mixing of fissile material packages with other types of Class 7 (radioactive) materials...

19 CFR 191.13 - Packaging materials.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 2 2010-04-01 2010-04-01 false Packaging materials. 191.13 Section 191.13 Customs... (CONTINUED) DRAWBACK General Provisions § 191.13 Packaging materials. (a) Imported packaging material... packaging material when used to package or repackage merchandise or articles exported or destroyed pursuant...

USING A CONTAINMENT VESSEL LIFTING APPARATUS FOR REMOTE OPERATIONS OF SHIPPING PACKAGES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Loftin, Bradley; Koenig, Richard

2013-08-08

The 9977 and the 9975 shipping packages are used in various nuclear facilities within the Department of Energy. These shipping packages are often loaded in designated areas with designs using overhead cranes or A-frames with lifting winches. However, there are cases where loading operations must be performed in remote locations where these facility infrastructures do not exist. For these locations, a lifting apparatus has been designed to lift the containment vessels partially out of the package for unloading operations to take place. Additionally, the apparatus allows for loading and closure of the containment vessel and subsequent pre-shipment testing. This papermore » will address the design of the apparatus and the challenges associated with the design, and it will describe the use of the apparatus.« less

Reducing the risk of contamination of sterile parenteral products via ready-to-use closure components.

PubMed

Curry, Wayne; Conway, Samuel; Goodfield, Clara; Miller, Kimberly; Mueller, Ronald L; Polini, Eugene

2010-12-01

The preparation of sterile parenteral products requires careful control of all ingredients, materials, and processes to ensure the final product has the identity and strength, and meets the quality and purity characteristics that it purports to possess. Contamination affecting these critical properties of parenteral products can occur in many ways and from many sources. The use of closures supplied by manufacturers in a ready-to-use state can be an effective method for reducing the risk of contamination and improving the quality of the drug product. This article will address contamination attributable to elastomeric container closure components and the regulatory requirements associated with container closure systems. Possible contaminants, including microorganisms, endotoxins, and chemicals, along with the methods by which these contaminants can enter the product will be reviewed. Such methods include inappropriate material selection, improper closure preparation processes, compromised container closure integrity, degradation of closures, and leaching of compounds from the closures.

VALVES FOR THE HIGH PRESSURE-HIGH TEMPERATURE (HP-HT) FLUORINATION SYSTEM. (Engineering Materials)

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1963-10-31

This package contains two drawings of valves which eliminate errors in the gravimetric oxide dilution procedure of U/sup 235/ measurement. Isotopic contaminatioNonen in the high pressure fluorination reactor was corrected by changing the manner in which the Cu tubing joins the valve and by modification of the bellows. The compact inlet system was modified to improve the precision of the spectrometer analyses. Changes were raade in the basic leak and the air operator, which is a diaphragm-type valve, so that the setting of the flow level is controlled by the closure spring adjustment screw. This capillary-type leak has increased controlmore » range and sraooth control characteristics. It is simple to construct, is remotely operated and is free from corrosion failure. (F.S.)« less

Automated Solid Phase Extraction (SPE) LC/NMR Applied to the Structural Analysis of Extractable Compounds from a Pharmaceutical Packaging Material of Construction.

PubMed

Norwood, Daniel L; Mullis, James O; Davis, Mark; Pennino, Scott; Egert, Thomas; Gonnella, Nina C

2013-01-01

The structural analysis (i.e., identification) of organic chemical entities leached into drug product formulations has traditionally been accomplished with techniques involving the combination of chromatography with mass spectrometry. These include gas chromatography/mass spectrometry (GC/MS) for volatile and semi-volatile compounds, and various forms of liquid chromatography/mass spectrometry (LC/MS or HPLC/MS) for semi-volatile and relatively non-volatile compounds. GC/MS and LC/MS techniques are complementary for structural analysis of leachables and potentially leachable organic compounds produced via laboratory extraction of pharmaceutical container closure/delivery system components and corresponding materials of construction. Both hyphenated analytical techniques possess the separating capability, compound specific detection attributes, and sensitivity required to effectively analyze complex mixtures of trace level organic compounds. However, hyphenated techniques based on mass spectrometry are limited by the inability to determine complete bond connectivity, the inability to distinguish between many types of structural isomers, and the inability to unambiguously determine aromatic substitution patterns. Nuclear magnetic resonance spectroscopy (NMR) does not have these limitations; hence it can serve as a complement to mass spectrometry. However, NMR technology is inherently insensitive and its ability to interface with chromatography has been historically challenging. This article describes the application of NMR coupled with liquid chromatography and automated solid phase extraction (SPE-LC/NMR) to the structural analysis of extractable organic compounds from a pharmaceutical packaging material of construction. The SPE-LC/NMR technology combined with micro-cryoprobe technology afforded the sensitivity and sample mass required for full structure elucidation. Optimization of the SPE-LC/NMR analytical method was achieved using a series of model compounds representing the chemical diversity of extractables. This study demonstrates the complementary nature of SPE-LC/NMR with LC/MS for this particular pharmaceutical application. The identification of impurities leached into drugs from the components and materials associated with pharmaceutical containers, packaging components, and materials has historically been done using laboratory techniques based on the combination of chromatography with mass spectrometry. Such analytical techniques are widely recognized as having the selectivity and sensitivity required to separate the complex mixtures of impurities often encountered in such identification studies, including both the identification of leachable impurities as well as potential leachable impurities produced by laboratory extraction of packaging components and materials. However, while mass spectrometry-based analytical techniques have limitations for this application, newer analytical techniques based on the combination of chromatography with nuclear magnetic resonance spectroscopy provide an added dimension of structural definition. This article describes the development, optimization, and application of an analytical technique based on the combination of chromatography and nuclear magnetic resonance spectroscopy to the identification of potential leachable impurities from a pharmaceutical packaging material. The complementary nature of the analytical techniques for this particular pharmaceutical application is demonstrated.

Container system for enabling commercial production of cryopreserved cell therapy products.

PubMed

Woods, Erik J; Bagchi, Aniruddha; Goebel, W Scott; Vilivalam, Vinod D; Vilivalam, Vinod D

2010-07-01

The expansion of cellular therapeutics will require large-scale manufacturing processes to expand and package cell products, which may not be feasible with current blood-banking bag technology. This study investigated the potential for freezing, storing and shipping cell therapy products using novel pharmaceutical-grade Crystal Zenith((R)) (CZ) plastic vials. CZ vials (0.5, 5 and 30 ml volume) with several closure systems were filled with mesenchymal stem cells and stored at either -85 or -196 degrees C for 6 months. Vials were tested for their ability to maintain cell viability, proliferative and differentiation capacity, as well as durability and integrity utilizing a 1-m drop test. As controls, 2 ml polypropylene vials were investigated under the same conditions. Post-thaw viability utilizing a dye exclusion assay was over 95% in all samples. Stored cells exhibited rapid recovery 2 h post-thaw and cultures were approximately 70% confluent within 5-7 days, consistent with nonfrozen controls and indicative of functional recovery. Doubling times were consistent over all vials. The doubling rate for cells from CZ vials were 2.14 + or - 0.83 days (1 week), 1.84 + or - 0.68 days (1 month) and 1.79 + or - 0.71 days (6 months), which were not significantly different compared with frozen and fresh controls. Cells recovered from the vials exhibited trilineage differentiation consistent with controls. As part of vial integrity via drop testing, no evidence of external damage was found on vial surfaces or on closure systems. Furthermore, the filled vials stored for 6 months were tested for container closure integrity. Vials removed from freezer conditions were transported to the test laboratory on dry ice and tested using pharmaceutical packaging tests, including dye ingress and microbial challenge. The results of all stoppered vials indicated container closure integrity with no failures. Pharmaceutical-grade plastic CZ vials, which are commercially used to package pharmaceutical products, are suitable for low-temperature storage and transport of mesenchymal stem cells, and are a scalable container system for commercial manufacturing and fill-finish operation of cell therapy products.

Green Packaging Management of Logistics Enterprises

NASA Astrophysics Data System (ADS)

Zhang, Guirong; Zhao, Zongjian

From the connotation of green logistics management, we discuss the principles of green packaging, and from the two levels of government and enterprises, we put forward a specific management strategy. The management of green packaging can be directly and indirectly promoted by laws, regulations, taxation, institutional and other measures. The government can also promote new investment to the development of green packaging materials, and establish specialized institutions to identify new packaging materials, standardization of packaging must also be accomplished through the power of the government. Business units of large scale through the packaging and container-based to reduce the use of packaging materials, develop and use green packaging materials and easy recycling packaging materials for proper packaging.

Integration of Electrical Resistivity and Seismic Refraction using Combine Inversion for Detecting Material Deposits of Impact Crater at Bukit Bunuh, Lenggong, Perak

NASA Astrophysics Data System (ADS)

Yusoh, R.; Saad, R.; Saidin, M.; Muhammad, S. B.; Anda, S. T.

2018-04-01

Both electrical resistivity and seismic refraction profiling has become a common method in pre-investigations for visualizing subsurface structure. The encouragement to use these methods is that combined of both methods can decrease the obscure inherent to the distinctive use of these methods. Both method have their individual software packages for data inversion, but potential to combine certain geophysical methods are restricted; however, the research algorithms that have this functionality was exists and are evaluated personally. The interpretation of subsurface were improve by combining inversion data from both method by influence each other models using closure coupling; thus, by implementing both methods to support each other which could improve the subsurface interpretation. These methods were applied on a field dataset from a pre-investigation for archeology in finding the material deposits of impact crater. There were no major changes in the inverted model by combining data inversion for this archetype which probably due to complex geology. The combine data analysis shows the deposit material start from ground surface to 20 meter depth which the class separation clearly separate the deposit material.

Sweat collection capsule

NASA Technical Reports Server (NTRS)

Greenleaf, J. E.; Delaplaine, R. W. (Inventor)

1980-01-01

A sweat collection capsule permitting quantitative collection of sweat is described. The device consists of a frame held immobile on the skin, a closure secured to the frame and absorbent material located next to the skin in a cavity formed by the frame and the closure. The absorbent material may be removed from the device by removing the closure from the frame while the frame is held immobile on the skin.

10 CFR 71.87 - Routine determinations.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Routine determinations. 71.87 Section 71.87 Energy NUCLEAR...; (c) Each closure device of the packaging, including any required gasket, is properly installed and secured and free of defects; (d) Any system for containing liquid is adequately sealed and has adequate...

10 CFR 71.87 - Routine determinations.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Routine determinations. 71.87 Section 71.87 Energy NUCLEAR...; (c) Each closure device of the packaging, including any required gasket, is properly installed and secured and free of defects; (d) Any system for containing liquid is adequately sealed and has adequate...

10 CFR 71.87 - Routine determinations.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Routine determinations. 71.87 Section 71.87 Energy NUCLEAR...; (c) Each closure device of the packaging, including any required gasket, is properly installed and secured and free of defects; (d) Any system for containing liquid is adequately sealed and has adequate...

10 CFR 71.87 - Routine determinations.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Routine determinations. 71.87 Section 71.87 Energy NUCLEAR...; (c) Each closure device of the packaging, including any required gasket, is properly installed and secured and free of defects; (d) Any system for containing liquid is adequately sealed and has adequate...

10 CFR 71.87 - Routine determinations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Routine determinations. 71.87 Section 71.87 Energy NUCLEAR...; (c) Each closure device of the packaging, including any required gasket, is properly installed and secured and free of defects; (d) Any system for containing liquid is adequately sealed and has adequate...

Packaging Your Training Materials

ERIC Educational Resources Information Center

Espeland, Pamela

1977-01-01

The types of packaging and packaging materials to use for training materials should be determined during the planning of the training programs, according to the packaging market. Five steps to follow in shopping for packaging are presented, along with a list of packaging manufacturers. (MF)

Landfill closure with dredged materials - desktop analysis.

DOT National Transportation Integrated Search

2014-08-01

This report describes a Rutgers University project for the New Jersey Department of : Transportation (NJDOT) designed to analyze the potential for closure of New Jersey : landfills using dredge material from existing Confined Disposal Facilities (CDF...

Multi-Material Closure Model for High-Order Finite Element Lagrangian Hydrodynamics

DOE PAGES

Dobrev, V. A.; Kolev, T. V.; Rieben, R. N.; ...

2016-04-27

We present a new closure model for single fluid, multi-material Lagrangian hydrodynamics and its application to high-order finite element discretizations of these equations [1]. The model is general with respect to the number of materials, dimension and space and time discretizations. Knowledge about exact material interfaces is not required. Material indicator functions are evolved by a closure computation at each quadrature point of mixed cells, which can be viewed as a high-order variational generalization of the method of Tipton [2]. This computation is defined by the notion of partial non-instantaneous pressure equilibration, while the full pressure equilibration is achieved bymore » both the closure model and the hydrodynamic motion. Exchange of internal energy between materials is derived through entropy considerations, that is, every material produces positive entropy, and the total entropy production is maximized in compression and minimized in expansion. Results are presented for standard one-dimensional two-material problems, followed by two-dimensional and three-dimensional multi-material high-velocity impact arbitrary Lagrangian–Eulerian calculations. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.« less

Multi-Material Closure Model for High-Order Finite Element Lagrangian Hydrodynamics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dobrev, V. A.; Kolev, T. V.; Rieben, R. N.

We present a new closure model for single fluid, multi-material Lagrangian hydrodynamics and its application to high-order finite element discretizations of these equations [1]. The model is general with respect to the number of materials, dimension and space and time discretizations. Knowledge about exact material interfaces is not required. Material indicator functions are evolved by a closure computation at each quadrature point of mixed cells, which can be viewed as a high-order variational generalization of the method of Tipton [2]. This computation is defined by the notion of partial non-instantaneous pressure equilibration, while the full pressure equilibration is achieved bymore » both the closure model and the hydrodynamic motion. Exchange of internal energy between materials is derived through entropy considerations, that is, every material produces positive entropy, and the total entropy production is maximized in compression and minimized in expansion. Results are presented for standard one-dimensional two-material problems, followed by two-dimensional and three-dimensional multi-material high-velocity impact arbitrary Lagrangian–Eulerian calculations. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.« less

77 FR 22504 - Hazardous Materials; Packages Intended for Transport by Aircraft

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-16

... material to absorb the entire contents of the inner packaging, before being placed in its outer package... combination packaging intended for the air transportation of liquid hazardous materials is capable of..., leakproof receptacle or intermediate packaging containing sufficient absorbent material to absorb the entire...

49 CFR 173.428 - Empty Class 7 (radioactive) materials packaging.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Empty Class 7 (radioactive) materials packaging... SHIPPERS-GENERAL REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Class 7 (Radioactive) Materials § 173.428 Empty Class 7 (radioactive) materials packaging. A packaging which previously contained Class 7 (radioactive...

19 CFR 10.2022 - Retail packaging materials and containers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 1 2014-04-01 2014-04-01 false Retail packaging materials and containers. 10.2022... Trade Promotion Agreement Rules of Origin § 10.2022 Retail packaging materials and containers. (a) Effect on tariff shift rule. Packaging materials and containers in which a good is packaged for retail...

19 CFR 10.461 - Retail packaging materials and containers.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Retail packaging materials and containers. 10.461... Free Trade Agreement Rules of Origin § 10.461 Retail packaging materials and containers. Packaging... requirement, the value of such packaging materials and containers will be taken into account as originating or...

40 CFR 146.71 - Closure.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Waste Injection Wells § 146.71 Closure. (a) Closure Plan. The owner or operator of a Class I hazardous waste injection well shall prepare, maintain, and comply with a plan for closure of the well that meets... of material to be used in plugging; (iv) The method of placement of the plugs; (v) Any proposed test...

9 CFR 381.144 - Packaging materials.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Packaging materials. 381.144 Section... Packaging materials. (a) Edible products may not be packaged in a container which is composed in whole or in... to health. All packaging materials must be safe for the intended use within the meaning of section...

19 CFR 10.922 - Retail packaging materials and containers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 1 2014-04-01 2014-04-01 false Retail packaging materials and containers. 10.922... Trade Promotion Agreement Rules of Origin § 10.922 Retail packaging materials and containers. (a) Effect on tariff shift rule. Packaging materials and containers in which a good is packaged for retail sale...

19 CFR 10.922 - Retail packaging materials and containers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Retail packaging materials and containers. 10.922... Trade Promotion Agreement Rules of Origin § 10.922 Retail packaging materials and containers. (a) Effect on tariff shift rule. Packaging materials and containers in which a good is packaged for retail sale...

19 CFR 10.461 - Retail packaging materials and containers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 1 2011-04-01 2011-04-01 false Retail packaging materials and containers. 10.461... Free Trade Agreement Rules of Origin § 10.461 Retail packaging materials and containers. Packaging materials and containers in which a good is packaged for retail sale, if classified with the good for which...

19 CFR 10.922 - Retail packaging materials and containers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 1 2012-04-01 2012-04-01 false Retail packaging materials and containers. 10.922... Trade Promotion Agreement Rules of Origin § 10.922 Retail packaging materials and containers. (a) Effect on tariff shift rule. Packaging materials and containers in which a good is packaged for retail sale...

19 CFR 10.1022 - Retail packaging materials and containers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 1 2012-04-01 2012-04-01 false Retail packaging materials and containers. 10.1022... Free Trade Agreement Rules of Origin § 10.1022 Retail packaging materials and containers. (a) Effect on tariff shift rule. Packaging materials and containers in which a good is packaged for retail sale, if...

19 CFR 10.3022 - Retail packaging materials and containers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Retail packaging materials and containers. 10.3022...-Colombia Trade Promotion Agreement Rules of Origin § 10.3022 Retail packaging materials and containers. (a) Effect on tariff shift rule. Packaging materials and containers in which a good is packaged for retail...

19 CFR 10.461 - Retail packaging materials and containers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Retail packaging materials and containers. 10.461... Free Trade Agreement Rules of Origin § 10.461 Retail packaging materials and containers. Packaging materials and containers in which a good is packaged for retail sale, if classified with the good for which...

19 CFR 10.3022 - Retail packaging materials and containers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 1 2014-04-01 2014-04-01 false Retail packaging materials and containers. 10.3022...-Colombia Trade Promotion Agreement Rules of Origin § 10.3022 Retail packaging materials and containers. (a) Effect on tariff shift rule. Packaging materials and containers in which a good is packaged for retail...

19 CFR 10.461 - Retail packaging materials and containers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 1 2014-04-01 2014-04-01 false Retail packaging materials and containers. 10.461... Free Trade Agreement Rules of Origin § 10.461 Retail packaging materials and containers. Packaging materials and containers in which a good is packaged for retail sale, if classified with the good for which...

19 CFR 10.539 - Retail packaging materials and containers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Retail packaging materials and containers. 10.539...-Singapore Free Trade Agreement Rules of Origin § 10.539 Retail packaging materials and containers. Packaging materials and containers in which a good is packaged for retail sale, if classified with the good for which...

19 CFR 10.1022 - Retail packaging materials and containers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 1 2014-04-01 2014-04-01 false Retail packaging materials and containers. 10.1022... Free Trade Agreement Rules of Origin § 10.1022 Retail packaging materials and containers. (a) Effect on tariff shift rule. Packaging materials and containers in which a good is packaged for retail sale, if...

19 CFR 10.461 - Retail packaging materials and containers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 1 2012-04-01 2012-04-01 false Retail packaging materials and containers. 10.461... Free Trade Agreement Rules of Origin § 10.461 Retail packaging materials and containers. Packaging materials and containers in which a good is packaged for retail sale, if classified with the good for which...

19 CFR 10.539 - Retail packaging materials and containers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 1 2014-04-01 2014-04-01 false Retail packaging materials and containers. 10.539...-Singapore Free Trade Agreement Rules of Origin § 10.539 Retail packaging materials and containers. Packaging materials and containers in which a good is packaged for retail sale, if classified with the good for which...

19 CFR 10.539 - Retail packaging materials and containers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 1 2011-04-01 2011-04-01 false Retail packaging materials and containers. 10.539...-Singapore Free Trade Agreement Rules of Origin § 10.539 Retail packaging materials and containers. Packaging materials and containers in which a good is packaged for retail sale, if classified with the good for which...

19 CFR 10.539 - Retail packaging materials and containers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 1 2012-04-01 2012-04-01 false Retail packaging materials and containers. 10.539...-Singapore Free Trade Agreement Rules of Origin § 10.539 Retail packaging materials and containers. Packaging materials and containers in which a good is packaged for retail sale, if classified with the good for which...

19 CFR 10.1022 - Retail packaging materials and containers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Retail packaging materials and containers. 10.1022... Free Trade Agreement Rules of Origin § 10.1022 Retail packaging materials and containers. (a) Effect on tariff shift rule. Packaging materials and containers in which a good is packaged for retail sale, if...

Sensory impacts of food-packaging interactions.

PubMed

Duncan, Susan E; Webster, Janet B

2009-01-01

Sensory changes in food products result from intentional or unintentional interactions with packaging materials and from failure of materials to protect product integrity or quality. Resolving sensory issues related to plastic food packaging involves knowledge provided by sensory scientists, materials scientists, packaging manufacturers, food processors, and consumers. Effective communication among scientists and engineers from different disciplines and industries can help scientists understand package-product interactions. Very limited published literature describes sensory perceptions associated with food-package interactions. This article discusses sensory impacts, with emphasis on oxidation reactions, associated with the interaction of food and materials, including taints, scalping, changes in food quality as a function of packaging, and examples of material innovations for smart packaging that can improve sensory quality of foods and beverages. Sensory evaluation is an important tool for improved package selection and development of new materials.

Vivostat®: an autologous fibrin sealant as useful adjunct in endoscopic transnasal CSF-leak repair.

PubMed

Tomazic, Peter Valentin; Edlinger, Stefan; Gellner, Verena; Koele, Wolfgang; Gerstenberger, Claus; Braun, Hannes; Mokry, Michael; Stammberger, Heinz

2015-06-01

The benefit of fibrin glue for reduction of postoperative CSF-leaks after endoscopic skull base surgery is not clearly evident in literature. However, its use is supposed to be beneficial in fixing grafting material. As of today there is no specific data available for otolaryngological procedures. A retrospective data analysis at a tertiary care referral center on 73 patients treated endoscopically transnasally for CSF-leaks at the ENT-department Graz between 2009 and 2012 was performed. Primary closure rate between conventional fibrin glue and autologous fibrin glue were analyzed. The Vivostat(®) system was used in 33 CSF-leak closures and in 40 cases conventional fibrin glue was used. Comparing the two methods the primary closure rate using the autologous Vivostat(®) system was 75.8 and 85.0 % with conventional fibrin glue. The secondary closure the rates were 90.9 % with Vivostat(®) 92.5 % with conventional fibrin glue. The Vivosat(®) system is a useful adjunct in endoscopic CSF-leak closure. Its advantages over conventional fibrin glue are its application system for fixation of grafting material particularly in underlay techniques. Despite this advantage it cannot replace grafting material or is a substitute for proper endoscopic closure which is reflected by the closure rates.

49 CFR 178.603 - Drop test.

Code of Federal Regulations, 2011 CFR

2011-10-01

... aluminum boxes, Composite packagings which are in the shape of a box Five—(one for each drop) First drop... impact. Where more than one orientation is possible for a given drop test, the orientation most likely to... example a closure or, for some 7 cylindrical drums, the welded longitudinal seam of the drum body. Boxes...

10 CFR 60.134 - Design of seals for shafts and boreholes.

Code of Federal Regulations, 2014 CFR

2014-01-01

... boreholes shall be designed so that following permanent closure they do not become pathways that compromise... pathway for groundwater to contact the waste packages or (2) For radionuclide migration through existing pathways. [48 FR 28222, June 21, 1983, as amended at 50 FR 29648, July 22, 1985] Design Criteria for the...

10 CFR 60.134 - Design of seals for shafts and boreholes.

Code of Federal Regulations, 2012 CFR

2012-01-01

... boreholes shall be designed so that following permanent closure they do not become pathways that compromise... pathway for groundwater to contact the waste packages or (2) For radionuclide migration through existing pathways. [48 FR 28222, June 21, 1983, as amended at 50 FR 29648, July 22, 1985] Design Criteria for the...

10 CFR 60.134 - Design of seals for shafts and boreholes.

Code of Federal Regulations, 2013 CFR

2013-01-01

... boreholes shall be designed so that following permanent closure they do not become pathways that compromise... pathway for groundwater to contact the waste packages or (2) For radionuclide migration through existing pathways. [48 FR 28222, June 21, 1983, as amended at 50 FR 29648, July 22, 1985] Design Criteria for the...

9 CFR 354.244 - Temperatures and cooling and freezing procedures.

Code of Federal Regulations, 2013 CFR

2013-01-01

... wrapped or packaged in water-vapor resistant cartons or the containers should be lined with heavy water... carcasses and to permit unsealed closure or sealing in such a manner that water-vapor loss from the product... cooling tank containing running cold tap water to remove the animal heat from the carcass. Carcasses shall...

9 CFR 354.244 - Temperatures and cooling and freezing procedures.

Code of Federal Regulations, 2012 CFR

2012-01-01

... wrapped or packaged in water-vapor resistant cartons or the containers should be lined with heavy water... carcasses and to permit unsealed closure or sealing in such a manner that water-vapor loss from the product... cooling tank containing running cold tap water to remove the animal heat from the carcass. Carcasses shall...

9 CFR 354.244 - Temperatures and cooling and freezing procedures.

Code of Federal Regulations, 2011 CFR

2011-01-01

... wrapped or packaged in water-vapor resistant cartons or the containers should be lined with heavy water... carcasses and to permit unsealed closure or sealing in such a manner that water-vapor loss from the product... cooling tank containing running cold tap water to remove the animal heat from the carcass. Carcasses shall...

9 CFR 354.244 - Temperatures and cooling and freezing procedures.

Code of Federal Regulations, 2014 CFR

2014-01-01

... wrapped or packaged in water-vapor resistant cartons or the containers should be lined with heavy water... carcasses and to permit unsealed closure or sealing in such a manner that water-vapor loss from the product... cooling tank containing running cold tap water to remove the animal heat from the carcass. Carcasses shall...

21 CFR 211.194 - Laboratory records.

Code of Federal Regulations, 2010 CFR

2010-04-01

... specific component, drug product container, closure, in-process material, or drug product, and lot tested... product container, closure, in-process material, or drug product tested. (7) The initials or signature of... of any testing and standardization of laboratory reference standards, reagents, and standard...

76 FR 82163 - Hazardous Materials: Harmonization With the United Nations Recommendations on the Transport of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-30

... combination packagings prohibit Class 1 (explosive) and Class 7 (radioactive) material to be offered for... transportation, Packaging and containers, Radioactive materials, Reporting and recordkeeping requirements... material, packing group assignments, special provisions, packaging authorizations, packaging sections, air...

Types, production and assessment of biobased food packaging materials

USDA-ARS?s Scientific Manuscript database

Food packaging performs an essential function, but packaging materials can have a negative impact on the environment. This book describes the latest advances in bio-based food packaging materials. Book provides a comprehensive review on bio-based, biodegradable and recycled materials and discusses t...

Efficacy of Antimicrobial Agents for Food Contact Applications: Biological Activity, Incorporation into Packaging, and Assessment Methods: A Review.

PubMed

Mousavi Khaneghah, Amin; Hashemi, Seyed Mohammad Bagher; Eş, Ismail; Fracassetti, Daniela; Limbo, Sara

2018-07-01

Interest in the utilization of antimicrobial active packaging for food products has increased in recent years. Antimicrobial active packaging involves the incorporation of antimicrobial compounds into packaging materials, with the aim of maintaining or extending food quality and shelf life. Plant extracts, essential oils, organic acids, bacteriocins, inorganic substances, enzymes, and proteins are used as antimicrobial agents in active packaging. Evaluation of the antimicrobial activity of packaging materials using different methods has become a critical issue for both food safety and the commercial utilization of such packaging technology. This article reviews the different types of antimicrobial agents used for active food packaging materials, the main incorporation techniques, and the assessment methods used to examine the antimicrobial activity of packaging materials, taking into account their safety as food contact materials.

9 CFR 317.24 - Packaging materials.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Packaging materials. 317.24 Section... INSPECTION AND CERTIFICATION LABELING, MARKING DEVICES, AND CONTAINERS General § 317.24 Packaging materials... packaging materials must be safe for their intended use within the meaning of section 409 of the Federal...

CENTRAL PLATEAU REMEDIATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

ROMINE, L.D.

2006-02-01

A systematic approach to closure planning is being implemented at the Hanford Site's Central Plateau to help achieve the goal of closure by the year 2035. The overall objective of Central Plateau remediation is to protect human health and the environment from the significant quantity of contaminated material that resulted from decades of plutonium production in support of the nation's defense. This goal will be achieved either by removing contaminants or placing the residual contaminated materials in a secure configuration that minimizes further migration to the groundwater and reduces the potential for inadvertent intrusion into contaminated sites. The approach tomore » Central Plateau cleanup used three key concepts--closure zones, closure elements, and closure process steps--to create an organized picture of actions required to complete remediation. These actions were merged with logic ties, constraints, and required resources to produce an integrated time-phased schedule and cost profile for Central Plateau closure. Programmatic risks associated with implementation of Central Plateau closure were identified and analyzed. Actions to mitigate the most significant risks are underway while high priority remediation projects continue to make progress.« less

Crack closure on rehydration of glass-ionomer materials.

PubMed

Sidhu, Sharanbir K; Pilecki, Peter; Sherriff, Martyn; Watson, Timothy F

2004-10-01

Moisture-sensitivity of immature glass-ionomer cements suggests that hydration-induced volumetric expansion might close and potentially heal established cracks. Crack closure in glass-ionomer cements (GICs) was observed following rehydration. Circular cavities were prepared in 15 teeth: 10 were restored with resin-modified GICs (5 with Fuji II LC and 5 with Photac-Fil) and 5 were restored with a conventional GIC (Fuji IX); all were dehydrated for 1 min with air and imaged immediately by confocal microscopy. Crack formation in each was located, after which water was placed on the surface and observed for 15 min via a CCD camera. Dehydration caused cracks with measurable gaps, while rehydration resulted in varying degrees of closure: closure was limited in the conventional GIC, and complete or near complete along part/s of the crack in the resin-modified GICs. In all, closure movement became imperceptible after the first 10 min. Statistical analysis indicated no significant difference between the closure behavior of all materials. However, the resin-modified GICs appeared to show a greater potential for closure of established cracks than the conventional GIC upon rehydration.

Practical fundamentals of glass, rubber, and plastic sterile packaging systems.

PubMed

Sacha, Gregory A; Saffell-Clemmer, Wendy; Abram, Karen; Akers, Michael J

2010-01-01

Sterile product packaging systems consist of glass, rubber, and plastic materials that are in intimate contact with the formulation. These materials can significantly affect the stability of the formulation. The interaction between the packaging materials and the formulation can also affect the appropriate delivery of the product. Therefore, a parenteral formulation actually consists of the packaging system as well as the product that it contains. However, the majority of formulation development time only considers the product that is contained in the packaging system. Little time is spent studying the interaction of the packaging materials with the contents. Interaction between the packaging and the contents only becomes a concern when problems are encountered. For this reason, there are few scientific publications that describe the available packaging materials, their advantages and disadvantages, and their important product attributes. This article was created as a reference for product development and describes some of the packaging materials and systems that are available for parenteral products.

Transition and closeout of the Fernald Closure Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bilson, H.E.; Terry, T.; Reising, J.

The U.S. Department of Energy (DOE) and Fluor Fernald have completed the majority of the cleanup of the Fernald Site. The over 1,000 acre complex for processing uranium has been demolished and soil contamination has been remediated. With acres of wetlands and prairies replacing the buildings and waste pits. At the end of the project the focus shifted to developing demonstrating the completion of the project and the contract, as well as ensuring a smooth transition of the facility from the DOE's Environmental Management (EM) Program to the DOE's Legacy Management (LM) Program. Working with the DOE, each portion ofmore » the closure contract was examined for specific closure definition. From this negotiation effort the Comprehensive Exit and Transition Plan (CE/T Plan) was written. The CE/T Plan is intended to assist DOE in the analysis that the site is ready for transfer into long-term stewardship (LTS) (also referred to as legacy management) and that Fluor Fernald, Inc. has satisfactorily completed the closure contract statement of work elements. Following the Lessons Learned from the closure of the Rocky Flats Site, the DOE's Legacy Management Program created a matrix of Transition Elements required to ensure adequate information was in place to allow the new prime contractor to perform the Legacy Management scope of work. The transition plan included over 1,000 elements broken down into functional areas and relied on specific Fernald Responsibility Transition Packages (RTPs) for detailed transition actions. The template for Closure and Transition Planning used at the Fernald Site was developed using the best Lessons Learned from across the DOE Complex. The template could be used for other sites, and lessons learned from this closure and transition will be appropriate for all closure projects. (authors)« less

EXTRACTION APPARATUS

DOEpatents

Ballard, A.E.; Brigham, H.R.

1958-10-28

An apparatus whereby relatlvely volatile solvents may be contacted with volatile or non-volatile material without certaln attendant hazards is described. A suitable apparatus for handling relatively volatlle liqulds may be constructed comprising a tank, and a closure covering the tank and adapted to be securely attached to an external suppont. The closure is provided with a rigidly mounted motor-driven agitator. This agitator is connected from the driving motor lnto the lnterlor of the tank through a gland adapted to be cooled witb inert gas thereby eliminating possible hazard due to frictional heat. The closure is arranged so that the tank may be removed from it without materially dlsturbing the closure which, as described, carrles the motor driven agitator and other parts.

21 CFR 181.22 - Certain substances employed in the manufacture of food-packaging materials.

Code of Federal Regulations, 2011 CFR

2011-04-01

... food-packaging materials. 181.22 Section 181.22 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT... of food-packaging materials. Prior to the enactment of the food additives amendment to the Federal... manufacturing practice for food-packaging materials includes the restriction that the quantity of any of these...

78 FR 29016 - Establishing Quality Assurance Programs for Packaging Used in Transport of Radioactive Material

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-16

... Establishing Quality Assurance Programs for Packaging Used in Transport of Radioactive Material AGENCY: Nuclear..., ``Establishing Quality Assurance Programs for Packaging Used in Transport of Radioactive Material.'' This draft... regulations for the packaging and transportation of radioactive material in Part 71 of Title 10 of the Code of...

49 CFR 171.1 - Applicability of Hazardous Materials Regulations (HMR) to persons and functions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... package or container or on a package or container containing a residue of a hazardous material. (5... bracing a hazardous materials package in a freight container or transport vehicle. (13) Segregating a hazardous materials package in a freight container or transport vehicle from incompatible cargo. (14...

49 CFR 171.1 - Applicability of Hazardous Materials Regulations (HMR) to persons and functions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... package or container or on a package or container containing a residue of a hazardous material. (5... bracing a hazardous materials package in a freight container or transport vehicle. (13) Segregating a hazardous materials package in a freight container or transport vehicle from incompatible cargo. (14...

49 CFR 171.1 - Applicability of Hazardous Materials Regulations (HMR) to persons and functions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... package or container or on a package or container containing a residue of a hazardous material. (5... bracing a hazardous materials package in a freight container or transport vehicle. (13) Segregating a hazardous materials package in a freight container or transport vehicle from incompatible cargo. (14...

49 CFR 171.1 - Applicability of Hazardous Materials Regulations (HMR) to persons and functions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... package or container or on a package or container containing a residue of a hazardous material. (5... bracing a hazardous materials package in a freight container or transport vehicle. (13) Segregating a hazardous materials package in a freight container or transport vehicle from incompatible cargo. (14...

49 CFR 172.316 - Packagings containing materials classed as ORM-D.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Packagings containing materials classed as ORM-D... INFORMATION, TRAINING REQUIREMENTS, AND SECURITY PLANS Marking § 172.316 Packagings containing materials classed as ORM-D. (a) Each non-bulk packaging containing a material classed as ORM-D must be marked on at...

The Effects of Loading History and Closure of the Fatigue Characteristics of Heat Treated Ti-6Al-2Sn-4Zr-6Mo

DTIC Science & Technology

1988-12-01

closure is dependent on the measurement technique used. Macha and others (24:213 ; 25:195) noted that the accuracy in determining the closure load was...Crack Closure, ASTM STP 982. 247-259. Philadelphia: American Society for Testing and Materials, 1988. 24. Macha , D. E. and others. "On the Variation of

The role of a detailed aqueous phase source release model in the LANL area G performance assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vold, E.L.; Shuman, R.; Hollis, D.K.

1995-12-31

A preliminary draft of the Performance Assessment for the Los Alamos National Laboratory (LANL) low-level radioactive waste disposal facility at Area G is currently being completed as required by Department of Energy orders. A detailed review of the inventory data base records and the existing models for source release led to the development of a new modeling capability to describe the liquid phase transport from the waste package volumes. Nuclide quantities are sorted down to four waste package release categories for modeling: rapid release, soil, concrete/sludge, and corrosion. Geochemistry for the waste packages was evaluated in terms of the equilibriummore » coefficients, Kds, and elemental solubility limits, Csl, interpolated from the literature. Percolation calculations for the base case closure cover show a highly skewed distribution with an average of 4 mm/yr percolation from the disposal unit bottom. The waste release model is based on a compartment representation of the package efflux, and depends on package size, percolation rate or Darcy flux, retardation coefficient, and moisture content.« less

9 CFR 317.24 - Packaging materials.

Code of Federal Regulations, 2014 CFR

2014-01-01

... supplier under whose brand name and firm name the material is marketed to the official establishment. The... packaging materials must be traceable to the applicable guaranty. (c) The guaranty by the packaging supplier.... Official establishments and packaging suppliers providing written guaranties to those official...

9 CFR 381.144 - Packaging materials.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., from the packaging supplier under whose brand name and firm name the material is marketed to the... packaging supplier will be accepted by Program inspectors to establish that the use of material complies.... Official establishments and packaging suppliers providing written guaranties to those official...

9 CFR 317.24 - Packaging materials.

Code of Federal Regulations, 2012 CFR

2012-01-01

... supplier under whose brand name and firm name the material is marketed to the official establishment. The... packaging materials must be traceable to the applicable guaranty. (c) The guaranty by the packaging supplier.... Official establishments and packaging suppliers providing written guaranties to those official...

9 CFR 381.144 - Packaging materials.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., from the packaging supplier under whose brand name and firm name the material is marketed to the... packaging supplier will be accepted by Program inspectors to establish that the use of material complies.... Official establishments and packaging suppliers providing written guaranties to those official...

9 CFR 381.144 - Packaging materials.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., from the packaging supplier under whose brand name and firm name the material is marketed to the... packaging supplier will be accepted by Program inspectors to establish that the use of material complies.... Official establishments and packaging suppliers providing written guaranties to those official...

9 CFR 317.24 - Packaging materials.

Code of Federal Regulations, 2013 CFR

2013-01-01

... supplier under whose brand name and firm name the material is marketed to the official establishment. The... packaging materials must be traceable to the applicable guaranty. (c) The guaranty by the packaging supplier.... Official establishments and packaging suppliers providing written guaranties to those official...

Groundwater Data Package for Hanford Assessments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thorne, Paul D.; Bergeron, Marcel P.; Williams, Mark D.

2006-01-31

This report presents data and interpreted information that supports the groundwater module of the System Assessment Capability (SAC) used in Hanford Assessments. The objective of the groundwater module is to predict movement of radioactive and chemical contaminants through the aquifer to the Columbia River or other potential discharge locations. This data package is being revised as part of the deliverables under the Characterization of Systems Project (#49139) aimed at providing documentation for assessments being conducted under the Hanford Assessments Project (#47042). Both of these projects are components of the Groundwater Remediation and Closure Assessments Projects, managed by the Management andmore » Integration Project (#47043).« less

Effectiveness of some recent antimicrobial packaging concepts.

PubMed

Vermeiren, L; Devlieghere, F; Debevere, J

2002-01-01

A new type of active packaging is the combination of food-packaging materials with antimicrobial substances to control microbial surface contamination of foods. For both migrating and non-migrating antimicrobial materials, intensive contact between the food product and packaging material is required and therefore potential food applications include especially vacuum or skin-packaged products, e.g. vacuum-packaged meat, fish, poultry or cheese. Several antimicrobial compounds have been combined with different types of carriers (plastic and rubber articles, paper-based materials, textile fibrils and food-packaging materials). Until now, however, few antimicrobial concepts have found applications as a food-packaging material. Antimicrobial packaging materials cannot legally be used in the EU at the moment. The potential use would require amendments of several different legal texts involving areas such as food additives, food packaging, hygiene, etc. The main objective of this paper is to provide a state of the art about the different types of antimicrobial concepts, their experimental development and commercialization, and to present a case study summarizing the results of investigations on the feasibility of a low-density polyethylene (LDPE)-film containing triclosan to inhibit microbial growth on food surfaces and consequently prolong shelf-life or improve microbial food safety. In contrast with the strong antimicrobial effect in in-vitro simulated vacuum-packaged conditions against the psychrotrophic food pathogen L. monocytogenes, the 1000 mg kg(-1) containing triclosan film did not effectively reduce spoilage bacteria and growth of L. monocytogenes on refrigerated vacuum-packaged chicken breasts stored at 7 degrees C.

77 FR 14445 - Leakage Tests on Packages for Shipment of Radioactive Material

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-09

... NUCLEAR REGULATORY COMMISSION [NRC-2011-0045] Leakage Tests on Packages for Shipment of..., ``Leakage Tests on Packages for Radioactive Material.'' ADDRESSES: You can access publicly available... Materials--Leakage Tests on Packages for Shipment'' approved February 1998. The NRC staff developed and...

77 FR 18871 - Administrative Guide for Verifying Compliance With Packaging Requirements for Shipment and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-28

... Packaging Requirements for Shipment and Receipt of Radioactive Material AGENCY: Nuclear Regulatory... with Packaging Requirements for Shipment and Receipt of Radioactive Material.'' This regulatory guide... for transporting licensed material under 10 CFR part 71, ``Packaging and Transportation of Radioactive...

Design, permitting, and construction issues associated with closure of the Panna Maria uranium tailings impoundment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Strachan, C.L.; Raabe, K.L.

1997-12-31

In 1992, Panna Maria Uranium Operations (PMUO) initiated licensing and engineering activities for closure of the Panna Maria mill and 150-acre tailings impoundment located in southeast Texas. Closure of the tailings impoundment is permitted by license amendment through the Texas Natural Resources Conservation Commission (TNRCC), and based on closure criteria outlined in Texas regulations. The closure plan for the Panna Maria tailings impoundment was submitted for Texas regulatory agency review in April 1993, with details of the closure plan modified in 1994, 1995, and 1996. The closure plan included a multi-layered cover over the regraded tailings surface which was designedmore » for long-term isolation of tailings, reduction of radon emanation to regulated levels, and reduction of infiltration to TNRCC-accepted levels. The cover and embankment slope surfaces and surrounding areas were designed to provide acceptable erosional stability as compared to runoff velocities from the Probable Maximum Precipitation event. Cover materials were selected from on-site materials and evaluated for suitability based on permeability, radon attenuation, and soil dispersivity characteristics. Off-site materials were used when necessary. The cover over the tailings has a maximum slope of 0.5 percent, and the regraded embankment slopes outside the perimeter of the impoundment have a maximum slope of 20 percent. All reclaimed slopes are covered with topsoil and revegetated. A riprap-lined channel is to be used to convey runoff from within the perimeter of the reclaimed impoundment to the north of the impoundment.« less

Report to Congress on the potential use of lead in the waste packages for a geologic repository at Yucca Mountain, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1989-12-01

In the Report of the Senate Committee on Appropriations accompanying the Energy and Water Appropriation Act for 1989, the Committee directed the Department of Energy (DOE) to evaluate the use of lead in the waste packages to be used in geologic repositories for spent nuclear fuel and high-level waste. The evaluation that was performed in response to this directive is presented in this report. This evaluation was based largely on a review of the technical literature on the behavior of lead, reports of work conducted in other countries, and work performed for the waste-management program being conducted by the DOE.more » The initial evaluation was limited to the potential use of lead in the packages to be used in the repository. Also, the focus of this report is post closure performance and not on retrievability and handling aspects of the waste package. 100 refs., 8 figs., 15 tabs.« less

Natural biopolymer-based nanocomposite films for packaging applications.

PubMed

Rhim, Jong-Whan; Ng, Perry K W

2007-01-01

Concerns on environmental waste problems caused by non-biodegradable petrochemical-based plastic packaging materials as well as the consumer's demand for high quality food products has caused an increasing interest in developing biodegradable packaging materials using annually renewable natural biopolymers such as polysaccharides and proteins. Inherent shortcomings of natural polymer-based packaging materials such as low mechanical properties and low water resistance can be recovered by applying a nanocomposite technology. Polymer nanocomposites, especially natural biopolymer-layered silicate nanocomposites, exhibit markedly improved packaging properties due to their nanometer size dispersion. These improvements include increased modulus and strength, decreased gas permeability, and increased water resistance. Additionally, biologically active ingredients can be added to impart the desired functional properties to the resulting packaging materials. Consequently, natural biopolymer-based nanocomposite packaging materials with bio-functional properties have a huge potential for application in the active food packaging industry. In this review, recent advances in the preparation of natural biopolymer-based films and their nanocomposites, and their potential use in packaging applications are addressed.

Diffusion and Leaching Behavior of Radionuclides in Category 3 Waste Encasement Concrete and Soil Fill Material – Summary Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mattigod, Shas V.; Wellman, Dawn M.; Bovaird, Chase C.

2011-08-31

One of the methods being considered for safely disposing of Category 3 low-level radioactive wastes is to encase the waste in concrete. Such concrete encasement would contain and isolate the waste packages from the hydrologic environment and would act as an intrusion barrier. The current plan for waste isolation consists of stacking low-level waste packages on a trench floor, surrounding the stacks with reinforced steel, and encasing these packages in concrete. These concrete-encased waste stacks are expected to vary in size with maximum dimensions of 6.4 m long, 2.7 m wide, and 4 m high. The waste stacks are expectedmore » to have a surrounding minimum thickness of 15 cm of concrete encasement. These concrete-encased waste packages are expected to withstand environmental exposure (solar radiation, temperature variations, and precipitation) until an interim soil cover or permanent closure cover is installed, and to remain largely intact thereafter. Any failure of concrete encasement may result in water intrusion and consequent mobilization of radionuclides from the waste packages. The mobilized radionuclides may escape from the encased concrete by mass flow and/or diffusion and move into the surrounding subsurface environment. Therefore, it is necessary to assess the performance of the concrete encasement structure and the ability of the surrounding soil to retard radionuclide migration. The retardation factors for radionuclides contained in the waste packages can be determined from measurements of diffusion coefficients for these contaminants through concrete and fill material. Some of the mobilization scenarios include (1) potential leaching of waste form before permanent closure cover is installed; (2) after the cover installation, long-term diffusion of radionuclides from concrete waste form into surrounding fill material; (3) diffusion of radionuclides from contaminated soils into adjoining concrete encasement and clean fill material. Additionally, the rate of diffusion of radionuclides may be affected by the formation of structural cracks in concrete, the carbonation of the buried waste form, and any potential effect of metallic iron (in the form of rebars) on the mobility of radionuclides. The radionuclides iodine-129 ({sup 129}I), technetium-99 ({sup 99}Tc), and uranium-238 ({sup 238}U) are identified as long-term dose contributors in Category 3 waste (Mann et al. 2001; Wood et al. 1995). Because of their anionic nature in aqueous solutions, {sup 129}I, {sup 99}Tc, and carbonate-complexed {sup 238}U may readily leach into the subsurface environment (Serne et al. 1989, 1992a, b, 1993, and 1995). The leachability and/or diffusion of radionuclide species must be measured to assess the long-term performance of waste grouts when contacted with vadose-zone pore water or groundwater. Although significant research has been conducted on the design and performance of cementitious waste forms, the current protocol conducted to assess radionuclide stability within these waste forms has been limited to the Toxicity Characteristic Leaching Procedure, Method 1311 Federal Registry (EPA 1992) and ANSI/ANS-16.1 leach test (ANSI 1986). These tests evaluate the performance under water-saturated conditions and do not evaluate the performance of cementitious waste forms within the context of waste repositories which are located within water-deficient vadose zones. Moreover, these tests assess only the diffusion of radionuclides from concrete waste forms and neglect evaluating the mechanisms of retention, stability of the waste form, and formation of secondary phases during weathering, which may serve as long-term secondary hosts for immobilization of radionuclides. The results of recent investigations conducted under arid and semi-arid conditions (Al-Khayat et al. 2002; Garrabrants et al. 2002; Garrabrants and Kosson 2003; Garrabrants et al. 2004; Gervais et al. 2004; Sanchez et al. 2002; Sanchez et al. 2003) provide valuable information suggesting structural and chemical changes to concrete waste forms which may affect contaminant containment and waste form performance. However, continued research is necessitated by the need to understand: the mechanism of contaminant release; the significance of contaminant release pathways; how waste form performance is affected by the full range of environmental conditions within the disposal facility; the process of waste form aging under conditions that are representative of processes occurring in response to changing environmental conditions within the disposal facility; the effect of waste form aging on chemical, physical, and radiological properties, and the associated impact on contaminant release. Recent reviews conducted by the National Academies of Science recognized the efficacy of cementitious materials for waste isolation, but further noted the significant shortcomings in our current understanding and testing protocol for evaluating the performance of various formulations.« less

The Model 9977 Radioactive Material Packaging Primer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abramczyk, G.

2015-10-09

The Model 9977 Packaging is a single containment drum style radioactive material (RAM) shipping container designed, tested and analyzed to meet the performance requirements of Title 10 the Code of Federal Regulations Part 71. A radioactive material shipping package, in combination with its contents, must perform three functions (please note that the performance criteria specified in the Code of Federal Regulations have alternate limits for normal operations and after accident conditions): Containment, the package must “contain” the radioactive material within it; Shielding, the packaging must limit its users and the public to radiation doses within specified limits; and Subcriticality, themore » package must maintain its radioactive material as subcritical« less

77 FR 36017 - Regulatory Guide 7.3, Procedures for Picking Up and Receiving Packages of Radioactive Material

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-15

... Receiving Packages of Radioactive Material AGENCY: Nuclear Regulatory Commission. ACTION: Notice of... Guide (RG) 7.3, ``Procedures for Picking Up and Receiving Packages of Radioactive Material.'' The guide..., ``Administrative Guide for Verifying Compliance with Packaging Requirements for Shipment and Receipt of Radioactive...

A pressure relaxation closure model for one-dimensional, two-material Lagrangian hydrodynamics based on the Riemann problem

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kamm, James R; Shashkov, Mikhail J

2009-01-01

Despite decades of development, Lagrangian hydrodynamics of strengthfree materials presents numerous open issues, even in one dimension. We focus on the problem of closing a system of equations for a two-material cell under the assumption of a single velocity model. There are several existing models and approaches, each possessing different levels of fidelity to the underlying physics and each exhibiting unique features in the computed solutions. We consider the case in which the change in heat in the constituent materials in the mixed cell is assumed equal. An instantaneous pressure equilibration model for a mixed cell can be cast asmore » four equations in four unknowns, comprised of the updated values of the specific internal energy and the specific volume for each of the two materials in the mixed cell. The unique contribution of our approach is a physics-inspired, geometry-based model in which the updated values of the sub-cell, relaxing-toward-equilibrium constituent pressures are related to a local Riemann problem through an optimization principle. This approach couples the modeling problem of assigning sub-cell pressures to the physics associated with the local, dynamic evolution. We package our approach in the framework of a standard predictor-corrector time integration scheme. We evaluate our model using idealized, two material problems using either ideal-gas or stiffened-gas equations of state and compare these results to those computed with the method of Tipton and with corresponding pure-material calculations.« less

75 FR 27205 - Hazardous Materials: Incorporation of Special Permits Into Regulations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-14

... transportation, Packaging and containers, Radioactive materials, Reporting and recordkeeping requirements... manufacture, marking, sale and use of certain packagings for transportation of hazardous materials. These... packagings prepared in accordance with Sec. 173.13. Authorize, for certain hazardous materials, external...

76 FR 41241 - Proposed Agency Information Collection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-13

... Material.'' The CoC defines the packaging, radioactive material content, and transportation restrictions... Radioactive Materials Packages; (3) Type of Request: New; (4) Purpose: This information collection is in... approved a radioactive material package as meeting the applicable safety standards [[Page 41242

49 CFR 173.25 - Authorized packagings and overpacks.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Authorized packagings and overpacks. 173.25...-GENERAL REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Preparation of Hazardous Materials for Transportation § 173.25 Authorized packagings and overpacks. (a) Authorized packages containing hazardous materials may...

49 CFR 173.453 - Fissile materials-exceptions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... noted. (a) An individual package containing 2 grams or less of fissile material. (b) An individual or bulk packaging containing 15 grams or less of fissile material provided the package has at least 200 grams of solid nonfissile material for every gram of fissile material. Lead, beryllium, graphite, and...

49 CFR 173.453 - Fissile materials-exceptions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... noted. (a) An individual package containing 2 grams or less of fissile material. (b) An individual or bulk packaging containing 15 grams or less of fissile material provided the package has at least 200 grams of solid nonfissile material for every gram of fissile material. Lead, beryllium, graphite, and...

49 CFR 173.453 - Fissile materials-exceptions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... noted. (a) An individual package containing 2 grams or less of fissile material. (b) An individual or bulk packaging containing 15 grams or less of fissile material provided the package has at least 200 grams of solid nonfissile material for every gram of fissile material. Lead, beryllium, graphite, and...

49 CFR 173.453 - Fissile materials-exceptions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... noted. (a) An individual package containing 2 grams or less of fissile material. (b) An individual or bulk packaging containing 15 grams or less of fissile material provided the package has at least 200 grams of solid nonfissile material for every gram of fissile material. Lead, beryllium, graphite, and...

49 CFR 173.453 - Fissile materials-exceptions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... noted. (a) An individual package containing 2 grams or less of fissile material. (b) An individual or bulk packaging containing 15 grams or less of fissile material provided the package has at least 200 grams of solid nonfissile material for every gram of fissile material. Lead, beryllium, graphite, and...

Savannah River Site Eastern Transportation Hub: A Concept For a DOE Eastern Packaging, Staging and Maintenance Center - 13143

DOE Office of Scientific and Technical Information (OSTI.GOV)

England, Jeffery L.; Adams, Karen; Maxted, Maxcine

2013-07-01

The Department of Energy (DOE) is working to de-inventory sites and consolidate hazardous materials for processing and disposal. The DOE administers a wide range of certified shipping packages for the transport of hazardous materials to include Special Nuclear Material (SNM), radioactive materials, sealed sources and radioactive wastes. A critical element to successful and safe transportation of these materials is the availability of certified shipping packages. There are over seven thousand certified packagings (i.e., Type B/Type AF) utilized within the DOE for current missions. The synergistic effects of consolidated maintenance, refurbishment, testing, certification, and costing of these services would allow formore » efficient management of the packagings inventory and to support anticipated future in-commerce shipping needs. The Savannah River Site (SRS) receives and ships radioactive materials (including SNM) and waste on a regular basis for critical missions such as consolidated storage, stabilization, purification, or disposition using H-Canyon and HB-Line. The Savannah River National Laboratory (SRNL) has the technical capability and equipment for all aspects of packaging management. SRS has the only active material processing facility in the DOE complex and is one of the sites of choice for nuclear material consolidation. SRS is a logical location to perform maintenance and periodic testing of the DOE fleet of certified packagings. This initiative envisions a DOE Eastern Packaging Staging and Maintenance Center (PSMC) at the SRS and a western hub at the Nevada National Security Site (NNSS), an active DOE Regional Disposal Site. The PSMC's would be the first place DOE would go to meet their radioactive packaging needs and the primary locations projects would go to disposition excess packaging for beneficial reuse. These two hubs would provide the centralized management of a packaging fleet rather than the current approach to design, procure, maintain and dispose of packagings on a project-by-project basis. This initiative provides significant savings in packaging costs and acceleration of project schedules. In addition to certified packaging, the PSMC would be well suited for select designs of 7A Type A packaging and Industrial Packaging. (authors)« less

40 CFR 280.70 - Temporary closure.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (UST) Out-of-Service UST Systems and Closure § 280.70 Temporary closure. (a) When an UST system is... the UST system is empty. The UST system is empty when all materials have been removed using commonly... the total capacity of the UST system, remain in the system. (b) When an UST system is temporarily...

40 CFR 280.70 - Temporary closure.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (UST) Out-of-Service UST Systems and Closure § 280.70 Temporary closure. (a) When an UST system is... the UST system is empty. The UST system is empty when all materials have been removed using commonly... the total capacity of the UST system, remain in the system. (b) When an UST system is temporarily...

40 CFR 280.70 - Temporary closure.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (UST) Out-of-Service UST Systems and Closure § 280.70 Temporary closure. (a) When an UST system is... the UST system is empty. The UST system is empty when all materials have been removed using commonly... the total capacity of the UST system, remain in the system. (b) When an UST system is temporarily...

40 CFR 280.70 - Temporary closure.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (UST) Out-of-Service UST Systems and Closure § 280.70 Temporary closure. (a) When an UST system is... the UST system is empty. The UST system is empty when all materials have been removed using commonly... the total capacity of the UST system, remain in the system. (b) When an UST system is temporarily...

40 CFR 280.70 - Temporary closure.

Code of Federal Regulations, 2012 CFR

2012-07-01

... (UST) Out-of-Service UST Systems and Closure § 280.70 Temporary closure. (a) When an UST system is... the UST system is empty. The UST system is empty when all materials have been removed using commonly... the total capacity of the UST system, remain in the system. (b) When an UST system is temporarily...

49 CFR 172.312 - Liquid hazardous materials in non-bulk packagings.

Code of Federal Regulations, 2014 CFR

2014-10-01

... offered or intended for transportation by aircraft, packages containing flammable liquids in inner... 49 Transportation 2 2014-10-01 2014-10-01 false Liquid hazardous materials in non-bulk packagings... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS...

49 CFR 172.312 - Liquid hazardous materials in non-bulk packagings.

Code of Federal Regulations, 2013 CFR

2013-10-01

... offered or intended for transportation by aircraft, packages containing flammable liquids in inner... 49 Transportation 2 2013-10-01 2013-10-01 false Liquid hazardous materials in non-bulk packagings... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS...

78 FR 1101 - Hazardous Materials: Harmonization With the United Nations Recommendations on the Transport of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-07

... packaging maintains an equivalent level of performance to the originally tested packaging design must be... material, packing group assignments, special provisions, packaging authorizations, packaging sections, air... responsibilities related to packaging design variation, manufacturer notification, and recordkeeping requirements...

78 FR 54775 - Bulk Packaging To Allow for Transfer of Hazardous Liquid Cargoes

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-06

... the selection and use of packaging in the transportation of hazardous materials. This rule will... Pipeline and Hazardous Materials Safety Administration SBA Small Business Administration U.S.C. United... materials to and from bulk packaging on vessels. The Coast Guard is expanding the list of bulk packaging...

Opportunities for cellulose nanomaterials in packaging films: a review and future trends

Treesearch

Nicole M. Stark

2016-01-01

Performance requirements for packaging films may include barrier properties, transparency, flexibility, and tensile strength. Conventional packaging materials such as plastic films and laminates, are typically made from petroleum-based polymers. Currently, there is a drive to develop sustainable packaging materials. These alternative materials must be able to be...

Antimicrobial activity of biodegradable polysaccharide and protein-based films containing active agents.

PubMed

Kuorwel, Kuorwel K; Cran, Marlene J; Sonneveld, Kees; Miltz, Joseph; Bigger, Stephen W

2011-04-01

Significant interest has emerged in the introduction of food packaging materials manufactured from biodegradable polymers that have the potential to reduce the environmental impacts associated with conventional packaging materials. Current technologies in active packaging enable effective antimicrobial (AM) packaging films to be prepared from biodegradable materials that have been modified and/or blended with different compatible materials and/or plasticisers. A wide range of AM films prepared from modified biodegradable materials have the potential to be used for packaging of various food products. This review examines biodegradable polymers derived from polysaccharides and protein-based materials for their potential use in packaging systems designed for the protection of food products from microbial contamination. A comprehensive table that systematically analyses and categorizes much of the current literature in this area is included in the review.

Leveraging Available Data to Support Extension of Transportation Packages Service Life

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dunn, K.; Abramczyk, G.; Bellamy, S.

Data obtained from testing shipping package materials have been leveraged to support extending the service life of select shipping packages while in nuclear materials transportation. Increasingly, nuclear material inventories are being transferred to an interim storage location where they will reside for extended periods of time. Use of a shipping package to store nuclear materials in an interim storage location has become more attractive for a variety of reasons. Shipping packages are robust and have a qualified pedigree for their performance in normal operation and accident conditions within the approved shipment period and storing nuclear material within a shipping packagemore » results in reduced operations for the storage facility. However, the shipping package materials of construction must maintain a level of integrity as specified by the safety basis of the storage facility through the duration of the storage period, which is typically well beyond the one year transportation window. Test programs have been established to obtain aging data on materials of construction that are the most sensitive/susceptible to aging in certain shipping package designs. The collective data are being used to support extending the service life of shipping packages in both transportation and storage.« less

Multi-layered Poly-Dimethylsiloxane As A Non-Hermetic Packaging Material For Medical MEMS

PubMed Central

Lachhman, S.; Zorman, C.A.; Ko, W.H.

2012-01-01

Poly-dimethylsiloxane (PDMS) is an attractive material for packaging implantable biomedical microdevices owing to its biocompatibility, ease in application, and bio-friendly mechanical properties. Unfortunately, devices encapsulated by PDMS lack the longevity for use in chronic implant applications due to defect-related moisture penetration through the packaging layer. This paper describes an effort to improve the performance of PDMS as packaging material by constructing the encapsulant from multiple, thin layers of PDMS as a part of a polymeric multi-material package PMID:23366225

Effect of novel food processing methods on packaging: structure, composition, and migration properties.

PubMed

Guillard, V; Mauricio-Iglesias, M; Gontard, N

2010-11-01

Classical stabilization techniques (thermal treatments) usually involve food to be packed after being processed. On the contrary and increasingly, novel food processing methods, such as high pressure or microwaves, imply that both packaging and foodstuff undergo the stabilization treatment. Moreover, novel treatments (UV light, irradiation, ozone, cold plasma) are specifically used for disinfection and sterilization of the packaging material itself. Therefore, in the last several years a number of papers have focused on the effects of these new treatments on food-packaging interactions with a special emphasis on chemical migration and safety concerns. New packaging materials merged on the market with specific interest regarding the environment (i.e. bio-sourced materials) or mechanical and barrier properties (i.e. nanocomposites packaging materials). It is time to evaluate the knowledge about how these in-package food technologies affect food/packaging interactions, and especially for novel biodegradable and/or active materials. This article presents the effect of high pressure treatment, microwave heating, irradiation, UV-light, ozone and, cold plasma treatment on food/packaging interactions.

Advances in Suture Material for Obstetric and Gynecologic Surgery

PubMed Central

Greenberg, James A; Clark, Rachel M

2009-01-01

Despite millennia of experience with wound closure biomaterials, no study or surgeon has yet identified the perfect suture for all situations. Tissue characteristics, tensile strength, reactivity, absorption rates, and handling properties should be taken into account when selecting a wound closure suture. This review discusses the wound healing process and the biomechanical properties of currently available suture materials to better understand how to choose suture material in obstetrics and gynecology. PMID:19826572

Ion-sculpting of nanopores in amorphous metals, semiconductors, and insulators

DOE Office of Scientific and Technical Information (OSTI.GOV)

George, H. Bola; Madi, Charbel S.; Aziz, Michael J.

2010-06-28

We report the closure of nanopores to single-digit nanometer dimensions by ion sculpting in a range of amorphous materials including insulators (SiO{sub 2} and SiN), semiconductors (a-Si), and metallic glasses (Pd{sub 80}Si{sub 20})--the building blocks of a single-digit nanometer electronic device. Ion irradiation of nanopores in crystalline materials (Pt and Ag) does not cause nanopore closure. Ion irradiation of c-Si pores below 100 deg. C and above 600 deg. C, straddling the amorphous-crystalline dynamic transition temperature, yields closure at the lower temperature but no mass transport at the higher temperature. Ion beam nanosculpting appears to be restricted to materials thatmore » either are or become amorphous during ion irradiation.« less

Development and Demonstration of Material Properties Database and Software for the Simulation of Flow Properties in Cementitious Materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, F.; Flach, G.

This report describes work performed by the Savannah River National Laboratory (SRNL) in fiscal year 2014 to develop a new Cementitious Barriers Project (CBP) software module designated as FLOExcel. FLOExcel incorporates a uniform database to capture material characterization data and a GoldSim model to define flow properties for both intact and fractured cementitious materials and estimate Darcy velocity based on specified hydraulic head gradient and matric tension. The software module includes hydraulic parameters for intact cementitious and granular materials in the database and a standalone GoldSim framework to manipulate the data. The database will be updated with new data asmore » it comes available. The software module will later be integrated into the next release of the CBP Toolbox, Version 3.0. This report documents the development efforts for this software module. The FY14 activities described in this report focused on the following two items that form the FLOExcel package; 1) Development of a uniform database to capture CBP data for cementitious materials. In particular, the inclusion and use of hydraulic properties of the materials are emphasized; and 2) Development of algorithms and a GoldSim User Interface to calculate hydraulic flow properties of degraded and fractured cementitious materials. Hydraulic properties are required in a simulation of flow through cementitious materials such as Saltstone, waste tank fill grout, and concrete barriers. At SRNL these simulations have been performed using the PORFLOW code as part of Performance Assessments for salt waste disposal and waste tank closure.« less

Flammability Analysis For Actinide Oxides Packaged In 9975 Shipping Containers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Laurinat, James E.; Askew, Neal M.; Hensel, Steve J.

2013-03-21

Packaging options are evaluated for compliance with safety requirements for shipment of mixed actinide oxides packaged in a 9975 Primary Containment Vessel (PCV). Radiolytic gas generation rates, PCV internal gas pressures, and shipping windows (times to reach unacceptable gas compositions or pressures after closure of the PCV) are calculated for shipment of a 9975 PCV containing a plastic bottle filled with plutonium and uranium oxides with a selected isotopic composition. G-values for radiolytic hydrogen generation from adsorbed moisture are estimated from the results of gas generation tests for plutonium oxide and uranium oxide doped with curium-244. The radiolytic generation ofmore » hydrogen from the plastic bottle is calculated using a geometric model for alpha particle deposition in the bottle wall. The temperature of the PCV during shipment is estimated from the results of finite element heat transfer analyses.« less

Edible packaging materials.

PubMed

Janjarasskul, Theeranun; Krochta, John M

2010-01-01

Research groups and the food and pharmaceutical industries recognize edible packaging as a useful alternative or addition to conventional packaging to reduce waste and to create novel applications for improving product stability, quality, safety, variety, and convenience for consumers. Recent studies have explored the ability of biopolymer-based food packaging materials to carry and control-release active compounds. As diverse edible packaging materials derived from various by-products or waste from food industry are being developed, the dry thermoplastic process is advancing rapidly as a feasible commercial edible packaging manufacturing process. The employment of nanocomposite concepts to edible packaging materials promises to improve barrier and mechanical properties and facilitate effective incorporation of bioactive ingredients and other designed functions. In addition to the need for a more fundamental understanding to enable design to desired specifications, edible packaging has to overcome challenges such as regulatory requirements, consumer acceptance, and scaling-up research concepts to commercial applications.

40 CFR 280.71 - Permanent closure and changes-in-service.

Code of Federal Regulations, 2011 CFR

2011-07-01

... UNDERGROUND STORAGE TANKS (UST) Out-of-Service UST Systems and Closure § 280.71 Permanent closure and changes... sludges. All tanks taken out of service permanently must also be either removed from the ground or filled with an inert solid material. (c) Continued use of an UST system to store a non-regulated substance is...

40 CFR 280.71 - Permanent closure and changes-in-service.

Code of Federal Regulations, 2013 CFR

2013-07-01

... UNDERGROUND STORAGE TANKS (UST) Out-of-Service UST Systems and Closure § 280.71 Permanent closure and changes... sludges. All tanks taken out of service permanently must also be either removed from the ground or filled with an inert solid material. (c) Continued use of an UST system to store a non-regulated substance is...

40 CFR 280.71 - Permanent closure and changes-in-service.

Code of Federal Regulations, 2012 CFR

2012-07-01

... UNDERGROUND STORAGE TANKS (UST) Out-of-Service UST Systems and Closure § 280.71 Permanent closure and changes... sludges. All tanks taken out of service permanently must also be either removed from the ground or filled with an inert solid material. (c) Continued use of an UST system to store a non-regulated substance is...

40 CFR 280.71 - Permanent closure and changes-in-service.

Code of Federal Regulations, 2014 CFR

2014-07-01

... UNDERGROUND STORAGE TANKS (UST) Out-of-Service UST Systems and Closure § 280.71 Permanent closure and changes... sludges. All tanks taken out of service permanently must also be either removed from the ground or filled with an inert solid material. (c) Continued use of an UST system to store a non-regulated substance is...

75 FR 17111 - Hazardous Materials Regulations: Combustible Liquids

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-05

... non-bulk packagings in a revised set of requirements for Class 3 materials, thereby eliminating the... material classed as a combustible liquid in a non-bulk packaging unless the combustible liquid is a... package for limited quantities for Class 7 (radioactive materials) could be transported as a combustible...

Effects of packaging materials on storage quality of peanut kernels

PubMed Central

Fu, Xiaoji; Xing, Shengping; Xiong, Huiwei; Min, Hua; Zhu, Xuejing; He, Jialin; Mu, Honglei

2018-01-01

In order to obtain optimum packaging materials for peanut kernels, the effects of four types of packaging materials on peanut storage quality (coat color, acid value, germination rate, relative damage, and prevention of aflatoxin contamination) were examined. The results showed that packaging materials had a major influence on peanut storage quality indexes. The color of the peanut seed coat packaged in the polyester/aluminum/polyamide/polyethylene (PET/AL/PA/PE) composite film bag did not change significantly during the storage period. Color deterioration was slower with polyamide/polyethylene (PA/PE) packaging materials than with polyethylene (PE) film bags and was slower in PE bags than in the woven bags. The use of PET/AL/PA/PE and PA/PE bags maintained peanut quality and freshness for more than one year and both package types resulted in better germination rates. There were significant differences between the four types of packaging materials in terms of controlling insect pests. The peanuts packaged in the highly permeable woven bags suffered serious invasion from insect pests, while both PET/AL/PA/PE and PA/PE bags effectively prevented insect infection. Peanuts stored in PET/AL/PA/PE and PA/PE bags were also better at preventing and controlling aflatoxin contamination. PMID:29518085

Multi-layered poly-dimethylsiloxane as a non-hermetic packaging material for medical MEMS.

PubMed

Lachhman, S; Zorman, C A; Ko, W H

2012-01-01

Poly-dimethylsiloxane (PDMS) is an attractive material for packaging implantable biomedical microdevices owing to its biocompatibility, ease in application, and bio-friendly mechanical properties. Unfortunately, devices encapsulated solely by PDMS lack the longevity for use in chronic implant applications due to defect-related moisture penetration through the packaging layer caused by conventional deposition processes such as spin coating. This paper describes an effort to improve the performance of PDMS as a packaging material by constructing the encapsulant from multiple, thin roller casted layers of PDMS as a part of a polymeric multi-material package.

Maldives. Package on population education for special interest groups developed.

PubMed

1995-01-01

The Population Education Program of the Non-Formal Education Center has developed a package of Population Education for Special Interest Groups comprising a learning package and fieldworker's guide. The learning package is especially developed for teaching population education for out-of-school populations. Special interest groups in Maldives include newly married couples, adolescents, and working youth. Produced under the guidance of UNESCO, Bangkok, the package contains 36 different materials such as posters, charts, leaflets, booklets, stories, and illustrated booklets which may be taught in 36 to 45 periods. The materials deal with eight themes, namely, family size and family welfare, population and resources, delayed marriage and parenthood, responsible parenthood, population-related values and beliefs, women in development, AIDS/STD, and respect for old people. Accompanying the learning package is the fieldworker's guide used to teach the package. It contains individual guides for each of the 36 learning materials. The guide gives the titles of the materials, format, objectives of the materials, messages, target groups, and an overview of the content of each learning materials. The methodologies used for teaching the learning materials include role playing, group discussion, questioning, brainstorming, survey, creative writing, problem-solving and evaluation. The package will be used by fieldworkers to conduct island-based population education courses. full text

Environmental Assessment of Packaging: The Consumer Point of View

PubMed

Van Dam YK

1996-09-01

When marketing environmentally responsible packaged products, the producer is confronted with consumer beliefs concerning the environmental friendliness of packaging materials. When making environmentally conscious packaging decisions, these consumer beliefs should be taken into account alongside the technical guidelines. Dutch consumer perceptions of the environmental friendliness of packaged products are reported and compared with the results of a life-cycle analysis assessment. It is shown that consumers judge environmental friendliness mainly from material and returnability. Furthermore, the consumer perception of the environmental friendliness of packaging material is based on the postconsumption waste, whereas the environmental effects of production are ignored. From the consumer beliefs concerning environmental friendliness implications are deduced for packaging policy and for environmental policy.KEY WORDS: Consumer behavior; Environment; Food; Packaging; Perception; Waste

Natural biopolimers in organic food packaging

NASA Astrophysics Data System (ADS)

Wieczynska, Justyna; Cavoski, Ivana; Chami, Ziad Al; Mondelli, Donato; Di Donato, Paola; Di Terlizzi, Biagio

2014-05-01

Concerns on environmental and waste problems caused by use of non-biodegradable and non-renewable based plastic packaging have caused an increase interest in developing biodegradable packaging using renewable natural biopolymers. Recently, different types of biopolymers like starch, cellulose, chitosan, casein, whey protein, collagen, egg white, soybean protein, corn zein, gelatin and wheat gluten have attracted considerable attention as potential food packaging materials. Recyclable or biodegradable packaging material in organic processing standards is preferable where possible but specific principles of packaging are not precisely defined and standards have to be assessed. There is evidence that consumers of organic products have specific expectations not only with respect to quality characteristics of processed food but also in social and environmental aspects of food production. Growing consumer sophistication is leading to a proliferation in food eco-label like carbon footprint. Biopolymers based packaging for organic products can help to create a green industry. Moreover, biopolymers can be appropriate materials for the development of an active surfaces designed to deliver incorporated natural antimicrobials into environment surrounding packaged food. Active packaging is an innovative mode of packaging in which the product and the environment interact to prolong shelf life or enhance safety or sensory properties, while maintaining the quality of the product. The work will discuss the various techniques that have been used for development of an active antimicrobial biodegradable packaging materials focusing on a recent findings in research studies. With the current focus on exploring a new generation of biopolymer-based food packaging materials with possible applications in organic food packaging. Keywords: organic food, active packaging, biopolymers , green technology

49 CFR 179.100-17 - Closures for openings.

Code of Federal Regulations, 2011 CFR

2011-10-01

... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120) § 179.100-17 Closures for...

49 CFR 179.100-17 - Closures for openings.

Code of Federal Regulations, 2014 CFR

2014-10-01

... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120) § 179.100-17 Closures for...

49 CFR 179.100-17 - Closures for openings.

Code of Federal Regulations, 2013 CFR

2013-10-01

... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120) § 179.100-17 Closures for...

76 FR 5215 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-28

... Compliance with Packaging Requirements for Shipment and Receipt of Radioactive Material,'' is temporarily... Code of Federal Regulations, Part 71, ``Packaging and Transportation of Radioactive Material'' (10 CFR... Compliance with Packaging Requirements for Shipments of Radioactive Materials,'' as an acceptable process for...

Trends in Food Packaging.

ERIC Educational Resources Information Center

Ott, Dana B.

1988-01-01

This article discusses developments in food packaging, processing, and preservation techniques in terms of packaging materials, technologies, consumer benefits, and current and potential food product applications. Covers implications due to consumer life-style changes, cost-effectiveness of packaging materials, and the ecological impact of…

Radiation treatment for sterilization of packaging materials

NASA Astrophysics Data System (ADS)

Haji-Saeid, Mohammad; Sampa, Maria Helena O.; Chmielewski, Andrzej G.

2007-08-01

Treatment with gamma and electron radiation is becoming a common process for the sterilization of packages, mostly made of natural or synthetic plastics, used in the aseptic processing of foods and pharmaceuticals. The effect of irradiation on these materials is crucial for packaging engineering to understand the effects of these new treatments. Packaging material may be irradiated either prior to or after filling. The irradiation prior to filling is usually chosen for dairy products, processed food, beverages, pharmaceutical, and medical device industries in the United States, Europe, and Canada. Radiation effects on packaging material properties still need further investigation. This paper summarizes the work done by different groups and discusses recent developments in regulations and testing procedures in the field of packaging technology.

10 CFR 71.15 - Exemption from classification as fissile material.

Code of Federal Regulations, 2012 CFR

2012-01-01

... subject to all other requirements of this part, except as noted. (a) Individual package containing 2 grams or less fissile material. (b) Individual or bulk packaging containing 15 grams or less of fissile material provided the package has at least 200 grams of solid nonfissile material for every gram of fissile...

10 CFR 71.15 - Exemption from classification as fissile material.

Code of Federal Regulations, 2010 CFR

2010-01-01

... subject to all other requirements of this part, except as noted. (a) Individual package containing 2 grams or less fissile material. (b) Individual or bulk packaging containing 15 grams or less of fissile material provided the package has at least 200 grams of solid nonfissile material for every gram of fissile...

10 CFR 71.15 - Exemption from classification as fissile material.

Code of Federal Regulations, 2013 CFR

2013-01-01

... subject to all other requirements of this part, except as noted. (a) Individual package containing 2 grams or less fissile material. (b) Individual or bulk packaging containing 15 grams or less of fissile material provided the package has at least 200 grams of solid nonfissile material for every gram of fissile...

10 CFR 71.15 - Exemption from classification as fissile material.

Code of Federal Regulations, 2011 CFR

2011-01-01

... subject to all other requirements of this part, except as noted. (a) Individual package containing 2 grams or less fissile material. (b) Individual or bulk packaging containing 15 grams or less of fissile material provided the package has at least 200 grams of solid nonfissile material for every gram of fissile...

10 CFR 71.15 - Exemption from classification as fissile material.

Code of Federal Regulations, 2014 CFR

2014-01-01

... subject to all other requirements of this part, except as noted. (a) Individual package containing 2 grams or less fissile material. (b) Individual or bulk packaging containing 15 grams or less of fissile material provided the package has at least 200 grams of solid nonfissile material for every gram of fissile...

21 CFR 179.45 - Packaging materials for use during the irradiation of prepackaged foods.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 3 2012-04-01 2012-04-01 false Packaging materials for use during the irradiation... OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) IRRADIATION IN THE... materials for use during the irradiation of prepackaged foods. The packaging materials identified in this...

21 CFR 179.45 - Packaging materials for use during the irradiation of prepackaged foods.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Packaging materials for use during the irradiation... OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) IRRADIATION IN THE... materials for use during the irradiation of prepackaged foods. The packaging materials identified in this...

21 CFR 179.45 - Packaging materials for use during the irradiation of prepackaged foods.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 3 2011-04-01 2011-04-01 false Packaging materials for use during the irradiation... OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) IRRADIATION IN THE... materials for use during the irradiation of prepackaged foods. The packaging materials identified in this...

21 CFR 179.45 - Packaging materials for use during the irradiation of prepackaged foods.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 3 2013-04-01 2013-04-01 false Packaging materials for use during the irradiation... OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) IRRADIATION IN THE... materials for use during the irradiation of prepackaged foods. The packaging materials identified in this...

Adequacy of a Small Quantity Site RH-TRU Waste Program in Meeting Proposed WIPP Characterization Objectives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Biedscheid, J.; Stahl, S.; Devarakonda, M.

2002-02-26

The first remote-handled transuranic (RH-TRU) waste is expected to be permanently disposed of at the Waste Isolation Pilot Plant (WIPP) during Fiscal Year (FY) 2003. The first RH-TRU waste shipments are scheduled from the Battelle Columbus Laboratories (BCL) to WIPP in order to facilitate compliance with BCL Decommissioning Project (BCLDP) milestones. Milestones requiring RH-TRU waste containerization and removal from the site by 2004 in order to meet a 2006 site closure goal, established by Congress in the Defense Facilities Closure Projects account, necessitated the establishment and implementation of a site-specific program to direct the packaging of BCLDP RH-TRU waste priormore » to the finalization of WIPP RH-TRU waste characterization requirements. The program was designed to collect waste data, including audio and videotape records of waste packaging, such that upon completion of waste packaging, comprehensive data records exist from which compliance with final WIPP RH-TRU waste characterization requirements can be demonstrated. With the BCLDP data records generated to date and the development by the U.S. Department of Energy (DOE)-Carlsbad Field Office (CBFO) of preliminary documents proposing the WIPP RH-TRU waste characterization program, it is possible to evaluate the adequacy of the BCLDP program with respect to meeting proposed characterization objectives. The BCLDP characterization program uses primarily acceptable knowledge (AK) and visual examination (VE) during waste packaging to characterize RH-TRU waste. These methods are used to estimate physical waste parameters, including weight percentages of metals, cellulosics, plastics, and rubber in the waste, and to determine the absence of prohibited items, including free liquids. AK combined with computer modeling is used to estimate radiological waste parameters, including total activity on a waste container basis, for the majority of BCLDP RH-TRU waste. AK combined with direct analysis is used to characterize radiological parameters for the small populations of the RH-TRU waste generated by the BCLDP. All characterization based on AK is verified. Per its design for comprehensive waste data collection, the BCLDP characterization program using AK and waste packaging procedures, including VE during packaging, meets the proposed WIPP RH-TRU waste characterization objectives. The conservative program design implemented generates certification data that will be adequate to meet any additional program requirements that may be imposed by the CBFO.« less

49 CFR 179.220-22 - Closure for openings.

Code of Federal Regulations, 2012 CFR

2012-10-01

... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.220-22 Closure for openings...

49 CFR 179.200-21 - Closures for openings.

Code of Federal Regulations, 2014 CFR

2014-10-01

... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.200-21 Closures for openings...

49 CFR 179.220-22 - Closure for openings.

Code of Federal Regulations, 2011 CFR

2011-10-01

... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.220-22 Closure for openings...

49 CFR 179.200-21 - Closures for openings.

Code of Federal Regulations, 2013 CFR

2013-10-01

... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.200-21 Closures for openings...

49 CFR 179.200-15 - Closures for manways.

Code of Federal Regulations, 2014 CFR

2014-10-01

... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.200-15 Closures for manways...

49 CFR 179.200-21 - Closures for openings.

Code of Federal Regulations, 2012 CFR

2012-10-01

... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.200-21 Closures for openings...

49 CFR 179.200-15 - Closures for manways.

Code of Federal Regulations, 2012 CFR

2012-10-01

... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.200-15 Closures for manways...

49 CFR 179.200-15 - Closures for manways.

Code of Federal Regulations, 2013 CFR

2013-10-01

... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.200-15 Closures for manways...

Influence of different materials on the thermal behavior of a CDIP-8 ceramic package

NASA Astrophysics Data System (ADS)

Weide, Kirsten; Keck, Christian

1999-08-01

The temperature distribution inside a package is determined by the heat transfer from the package to the ambient, depending on the heat conductivities of the different used materials. With the help of finite element simulations the thermal behavior of the package can be characterized. In precise simulations convection and radiation effects have to be taken into account. In this paper the influence of different materials like the ceramic, the pin and die attach material and adhesive material between the chip and the die attach on the thermal resistance of the ceramic package will be investigated. A finite element model of the ceramic package including a voltage regulator on the chip was created. The simulations were carried out with the finite element program ANSYS. An easy way to take the radiation effect into account, which normally is difficult to handle in the simulation, will be shown. The results of the simulations are verified by infrared measurements. A comparison of the thermal resistance between the best case and worst case for different package materials was done. The thermal conductivity of the ceramic material shows the strongest influence on the thermal resistance.

Degradation Behavior and Accelerated Weathering of Composite Boards Produced from Waste Tetra Pak® Packaging Materials

Treesearch

Nural Yilgor; Coskun Kose; Evren Terzi; Aysel Kanturk Figen; Rebecca Ibach; S. Nami Kartal; Sabriye Piskin

2014-01-01

Manufacturing panels from Tetra Pak® (TP) packaging material might be an alternative to conventional wood-based panels. This study evaluated some chemical and physical properties as well as biological, weathering, and fire performance of panels with and without zinc borate (ZnB) by using shredded TP packaging cartons. Such packaging material, a worldwide well-known...

9 CFR 381.144 - Packaging materials.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., from the packaging supplier under whose brand name and firm name the material is marketed to the... distinguishing brand name or code designation appearing on the packaging material shipping container; must....13) will be acceptable. The management of the establishment must maintain a file containing...

Teaching Old Packaging New Tricks - 12593

DOE Office of Scientific and Technical Information (OSTI.GOV)

England, Jeffery L.; Shuler, James M.

2012-07-01

Waste disposition campaigns have been an industry and government focus area since the mid- 1970's. With increased focus on this issue, and a lot of hard work, most waste packaging and transportation issues have been addressed. The material has been successfully shipped and dis-positioned. DOE has successfully de-inventoried materials from multiple sites to meet material consolidation, footprint reduction, nonproliferation, and regulatory obligations with cost savings from reduced maintenance and regulatory compliance. There has been a wide range of certified shipping packagings for the transportation of hazardous materials to meet most of the waste needs. The remaining materials are problematic, generallymore » low volume, and do not meet the certified content of the existing inventory of packaging. Designing, testing and certifying new packaging designs can be a long and expensive process and for small volumes of material it is cost prohibitive. One very cost effective option is to lease and use a certified packaging to overpack waste containers. There are many robust certified packagings available with the capability to envelope the waste content. The capability to use inner containers, inside the current fleet of certified casks or packaging, to address specific content problems of additional shielding (e.g., U-233) or containment (e.g., sodium bonded nuclear material) has successfully expanded the capability for timely cost effective shipment of unique contents. This option has been used successfully in the NAC-LWT, T-3 and other packagings. (authors)« less

Container Closure Integrity Testing of Prefilled Syringes.

PubMed

Peláez, Sarah S; Mahler, Hanns-Christian; Matter, Anja; Koulov, Atanas; Singh, Satish K; Germershaus, Oliver; Mathaes, Roman

2018-04-05

Prefilled syringes (PFSs) are increasingly preferred over vials as container closure systems (CCSs) for injectable drug products when facilitated or self-administration is required. However, PFSs are more complex compared to CCSs consisting of vial, rubber stopper, and crimp cap. Container closure integrity (CCI) assurance and verification has been a specific challenge for PFSs as they feature several sealing areas. A comprehensive understanding of the CCS is necessary for an appropriate CCI assessment as well as for packaging development and qualification. A comprehensive CCI assessment of 6 different PFSs from 3 different manufacturers (including 1 polymeric PFS) was conducted using helium leak testing. PFS components were manipulated to systematically assess the contribution of the different sealing areas to CCI, namely rigid needle shield (RNS)/needle, RNS/tip cone, and the individual ribs of a syringe plunger. The polymeric PFS required an equilibrium measurement for accurate container closure integrity testing. The different sealing areas and a single plunger rib were shown to provide adequate CCI. Acceptable tip cap movement until the point of CCI failure was estimated. The assessment of acceptable tip cap movement demonstrated the importance of considering the RNS/tip cone seal design to ensure CCI of the PFS upon post assembly possesses and shipment. Copyright © 2018 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

Quality and safety aspects of meat products as affected by various physical manipulations of packaging materials.

PubMed

Lee, Keun Taik

2010-09-01

This article explores the effects of physically manipulated packaging materials on the quality and safety of meat products. Recently, innovative measures for improving quality and extending the shelf-life of packaged meat products have been developed, utilizing technologies including barrier film, active packaging, nanotechnology, microperforation, irradiation, plasma and far-infrared ray (FIR) treatments. Despite these developments, each technology has peculiar drawbacks which will need to be addressed by meat scientists in the future. To develop successful meat packaging systems, key product characteristics affecting stability, environmental conditions during storage until consumption, and consumers' packaging expectations must all be taken into consideration. Furthermore, the safety issues related to packaging materials must also be taken into account when processing, packaging and storing meat products.

Packaging films for electronic and space-related hardware

NASA Astrophysics Data System (ADS)

Shon, E. M.; Hamberg, O.

1985-08-01

Flexible packaging films are used to bag and/or wrap precision cleaned electronic or space hardware to protect them from environmental degradation during shipping and storage. Selection of packaging films depends on a knowledge of product requirements and packaging film characteristics. The literature presently available on protective packaging films has been updated to include new materials and to amplify space-related applications. Presently available packaging film materials are compared for their various characteristics: electrostatic discharge (ESD) control, flame retardancy, water vapor transmission rate, particulate shedding, molecular contamination, and transparency. The tradeoff between product requirements and the characteristics of the packaging films available are discussed. Selection considerations are given for the application of specific materials of space hardware-related applications. Applications for intimate, environmental, and electrostatic protective packaging are discussed.

KymoKnot: A web server and software package to identify and locate knots in trajectories of linear or circular polymers.

PubMed

Tubiana, Luca; Polles, Guido; Orlandini, Enzo; Micheletti, Cristian

2018-06-07

The KymoKnot software package and web server identifies and locates physical knots or proper knots in a series of polymer conformations. It is mainly intended as an analysis tool for trajectories of linear or circular polymers, but it can be used on single instances too, e.g. protein structures in PDB format. A key element of the software package is the so-called minimally interfering chain closure algorithm that is used to detect physical knots in open chains and to locate the knotted region in both open and closed chains. The web server offers a user-friendly graphical interface that identifies the knot type and highlights the knotted region on each frame of the trajectory, which the user can visualize interactively from various viewpoints. The dynamical evolution of the knotted region along the chain contour is presented as a kymograph. All data can be downloaded in text format. The KymoKnot package is licensed under the BSD 3-Clause licence. The server is publicly available at http://kymoknot.sissa.it/kymoknot/interactive.php .

Life and stability testing of packaged low-cost energy storage materials

NASA Astrophysics Data System (ADS)

Frysinger, G. R.

1980-07-01

A low-cost laminated plastic film which is used to contain a Glauber's salt-based phase change thermal energy storage material in sausage like containers called Chubs was developed. Results of tests performed on the Chub packages themselves and on the thermal energy storage capacity of the packaged phase change material are described. From the test results, a set of specifications was drawn up for a film material which will satisfactorily contain the phase change material under anticipated operating conditions. Calorimetric testing of the phase change material with thermal cycling indicates that a design capacity of 45 to 50 Btu/lb for a delta T of 30 F can be used for the packaged material.

Material flow analysis for an industry - A case study in packaging

USGS Publications Warehouse

Amey, E.B.; Sandgren, K.

1996-01-01

The basic materials used in packaging are glass, metals (primarily aluminum and steel), an ever-growing range of plastics, paper and paperboard, wood, textiles for bags, and miscellaneous other materials (such as glues, inks, and other supplies). They are fabricated into rigid, semi-rigid, or flexible containers. The most common forms of these containers include cans, drums, bottles, cartons, boxes, bags, pouches, and wraps. Packaging products are, for the most part, low cost, bulky products that are manufactured close to their customers. There is virtually no import or export of packaging products. A material flow analysis can be developed that looks at all inputs to an industrial sector, inventories the losses in processing, and tracks the fate of the material after its useful life. An example is presented that identifies the material inputs to the packaging industry, and addresses the ultimate fate of the materials used. ?? 1996 International Association for Mathematical Geology.

Packaging food for radiation processing

NASA Astrophysics Data System (ADS)

Komolprasert, Vanee

2016-12-01

Irradiation can play an important role in reducing pathogens that cause food borne illness. Food processors and food safety experts prefer that food be irradiated after packaging to prevent post-irradiation contamination. Food irradiation has been studied for the last century. However, the implementation of irradiation on prepackaged food still faces challenges on how to assess the suitability and safety of these packaging materials used during irradiation. Irradiation is known to induce chemical changes to the food packaging materials resulting in the formation of breakdown products, so called radiolysis products (RP), which may migrate into foods and affect the safety of the irradiated foods. Therefore, the safety of the food packaging material (both polymers and adjuvants) must be determined to ensure safety of irradiated packaged food. Evaluating the safety of food packaging materials presents technical challenges because of the range of possible chemicals generated by ionizing radiation. These challenges and the U.S. regulations on food irradiation are discussed in this article.

Fungal mycelium and cotton plant materials in the manufacture of biodegradable molded packaging material: Evaluation study of select blends of cotton byproducts

USDA-ARS?s Scientific Manuscript database

The primary material used by the packaging industry is extruded polystyrene foam, which is commonly marketed as Styrofoam™. In its original formulation, Styrofoam™ is resistant to photolysis and effectively does not decompose. The light weight of Styrofoam™ packaging materials reduces the likelihood...

19 CFR 10.878 - Packaging and packing materials and containers for retail sale and for shipment.

Code of Federal Regulations, 2014 CFR

2014-04-01

... retail sale and for shipment. 10.878 Section 10.878 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... materials and containers for retail sale and for shipment. Packaging materials and containers in which a good is packaged for retail sale and packing materials and containers for shipment are to be...

19 CFR 10.815 - Packaging and packing materials and containers for retail sale and for shipment.

Code of Federal Regulations, 2012 CFR

2012-04-01

... retail sale and for shipment. 10.815 Section 10.815 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... materials and containers for retail sale and for shipment. Packaging materials and containers in which a good is packaged for retail sale and packing materials and containers for shipment are to be...

19 CFR 10.815 - Packaging and packing materials and containers for retail sale and for shipment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... retail sale and for shipment. 10.815 Section 10.815 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... materials and containers for retail sale and for shipment. Packaging materials and containers in which a good is packaged for retail sale and packing materials and containers for shipment are to be...

19 CFR 10.815 - Packaging and packing materials and containers for retail sale and for shipment.

Code of Federal Regulations, 2013 CFR

2013-04-01

... retail sale and for shipment. 10.815 Section 10.815 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... materials and containers for retail sale and for shipment. Packaging materials and containers in which a good is packaged for retail sale and packing materials and containers for shipment are to be...

19 CFR 10.878 - Packaging and packing materials and containers for retail sale and for shipment.

Code of Federal Regulations, 2013 CFR

2013-04-01

... retail sale and for shipment. 10.878 Section 10.878 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... materials and containers for retail sale and for shipment. Packaging materials and containers in which a good is packaged for retail sale and packing materials and containers for shipment are to be...

19 CFR 10.775 - Packaging and packing materials and containers for retail sale and for shipment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... retail sale and for shipment. 10.775 Section 10.775 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... materials and containers for retail sale and for shipment. Packaging materials and containers in which a good is packaged for retail sale and packing materials and containers for shipment are to be...

19 CFR 10.815 - Packaging and packing materials and containers for retail sale and for shipment.

Code of Federal Regulations, 2014 CFR

2014-04-01

... retail sale and for shipment. 10.815 Section 10.815 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... materials and containers for retail sale and for shipment. Packaging materials and containers in which a good is packaged for retail sale and packing materials and containers for shipment are to be...

19 CFR 10.775 - Packaging and packing materials and containers for retail sale and for shipment.

Code of Federal Regulations, 2011 CFR

2011-04-01

... retail sale and for shipment. 10.775 Section 10.775 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... materials and containers for retail sale and for shipment. Packaging materials and containers in which a good is packaged for retail sale and packing materials and containers for shipment are to be...

19 CFR 10.775 - Packaging and packing materials and containers for retail sale and for shipment.

Code of Federal Regulations, 2013 CFR

2013-04-01

... retail sale and for shipment. 10.775 Section 10.775 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... materials and containers for retail sale and for shipment. Packaging materials and containers in which a good is packaged for retail sale and packing materials and containers for shipment are to be...

19 CFR 10.878 - Packaging and packing materials and containers for retail sale and for shipment.

Code of Federal Regulations, 2012 CFR

2012-04-01

... retail sale and for shipment. 10.878 Section 10.878 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... materials and containers for retail sale and for shipment. Packaging materials and containers in which a good is packaged for retail sale and packing materials and containers for shipment are to be...

19 CFR 10.815 - Packaging and packing materials and containers for retail sale and for shipment.

Code of Federal Regulations, 2011 CFR

2011-04-01

... retail sale and for shipment. 10.815 Section 10.815 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... materials and containers for retail sale and for shipment. Packaging materials and containers in which a good is packaged for retail sale and packing materials and containers for shipment are to be...

19 CFR 10.878 - Packaging and packing materials and containers for retail sale and for shipment.

Code of Federal Regulations, 2011 CFR

2011-04-01

... retail sale and for shipment. 10.878 Section 10.878 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... materials and containers for retail sale and for shipment. Packaging materials and containers in which a good is packaged for retail sale and packing materials and containers for shipment are to be...

19 CFR 10.775 - Packaging and packing materials and containers for retail sale and for shipment.

Code of Federal Regulations, 2014 CFR

2014-04-01

... retail sale and for shipment. 10.775 Section 10.775 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... materials and containers for retail sale and for shipment. Packaging materials and containers in which a good is packaged for retail sale and packing materials and containers for shipment are to be...

19 CFR 10.775 - Packaging and packing materials and containers for retail sale and for shipment.

Code of Federal Regulations, 2012 CFR

2012-04-01

... retail sale and for shipment. 10.775 Section 10.775 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... materials and containers for retail sale and for shipment. Packaging materials and containers in which a good is packaged for retail sale and packing materials and containers for shipment are to be...

Development of expert system for biobased polymer material selection: food packaging application.

PubMed

Sanyang, M L; Sapuan, S M

2015-10-01

Biobased food packaging materials are gaining more attention owing to their intrinsic biodegradable nature and renewability. Selection of suitable biobased polymers for food packaging applications could be a tedious task with potential mistakes in choosing the best materials. In this paper, an expert system was developed using Exsys Corvid software to select suitable biobased polymer materials for packaging fruits, dry food and dairy products. If - Then rule based system was utilized to accomplish the material selection process whereas a score system was formulated to facilitate the ranking of selected materials. The expert system selected materials that satisfied all constraints and selection results were presented in suitability sequence depending on their scores. The expert system selected polylactic acid (PLA) as the most suitable material.

Development of active, nanoparticle, antimicrobial technologies for muscle-based packaging applications.

PubMed

Morris, Michael A; Padmanabhan, Sibu C; Cruz-Romero, Malco C; Cummins, Enda; Kerry, Joseph P

2017-10-01

Fresh and processed muscle-based foods are highly perishable food products and packaging plays a crucial role in providing containment so that the full effect of preservation can be achieved through the provision of shelf-life extension. Conventional packaging materials and systems have served the industry well, however, greater demands are being placed upon industrial packaging formats owing to the movement of muscle-based products to increasingly distant markets, as well as increased customer demands for longer product shelf-life and storage capability. Consequently, conventional packaging materials and systems will have to evolve to meet these challenges. This review presents some of the new strategies that have been developed by employing novel nanotechnological concepts which have demonstrated some promise in significantly extending the shelf-life of muscle-based foods by providing commercially-applicable, antimicrobially-active, smart packaging solutions. The primary focus of this paper is applied to subject aspects, such as; material chemistries employed, forming methods utilised, interactions of the packaging functionalities including nanomaterials employed with polymer substrates and how such materials ultimately affect microbes. In order that such materials become industrially feasible, it is important that safe, stable and commercially-viable packaging materials are shown to be producible and effective in order to gain public acceptance, legislative approval and industrial adoption. Copyright © 2017. Published by Elsevier Ltd.

49 CFR 172.312 - Liquid hazardous materials in non-bulk packagings.

Code of Federal Regulations, 2011 CFR

2011-10-01

... offered or intended for transportation by aircraft, packages containing flammable liquids in inner... offered or intended for transportation by aircraft, packages containing flammable liquids in inner... 49 Transportation 2 2011-10-01 2011-10-01 false Liquid hazardous materials in non-bulk packagings...

49 CFR 172.312 - Liquid hazardous materials in non-bulk packagings.

Code of Federal Regulations, 2012 CFR

2012-10-01

... offered or intended for transportation by aircraft, packages containing flammable liquids in inner... offered or intended for transportation by aircraft, packages containing flammable liquids in inner... 49 Transportation 2 2012-10-01 2012-10-01 false Liquid hazardous materials in non-bulk packagings...

49 CFR 172.312 - Liquid hazardous materials in non-bulk packagings.

Code of Federal Regulations, 2010 CFR

2010-10-01

... offered or intended for transportation by aircraft, packages containing flammable liquids in inner... offered or intended for transportation by aircraft, packages containing flammable liquids in inner... 49 Transportation 2 2010-10-01 2010-10-01 false Liquid hazardous materials in non-bulk packagings...

Recharge Data Package for Hanford Single-Shell Tank Waste Management Areas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fayer, Michael J.; Keller, Jason M.

2007-09-24

Pacific Northwest National Laboratory (PNNL) assists CH2M HILL Hanford Group, Inc., in its preparation of the Resource Conservation and Recovery Act (RCRA) Facility Investigation report. One of the PNNL tasks is to use existing information to estimate recharge rates for past and current conditions as well as future scenarios involving cleanup and closure of tank farms. The existing information includes recharge-relevant data collected during activities associated with a host of projects, including those of RCRA, the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), the CH2M HILL Tank Farm Vadose Zone Project, and the PNNL Remediation and Closure Science Project.more » As new information is published, the report contents can be updated. The objective of this data package was to use published data to provide recharge estimates for the scenarios being considered in the RCRA Facility Investigation. Recharge rates were estimated for areas that remain natural and undisturbed, areas where the vegetation has been disturbed, areas where both the vegetation and the soil have been disturbed, and areas that are engineered (e.g., surface barrier). The recharge estimates supplement the estimates provided by PNNL researchers in 2006 for the Hanford Site using additional field measurements and model analysis using weather data through 2006.« less

Chlorhexidine hexametaphosphate as a wound care material coating: antimicrobial efficacy, toxicity and effect on healing.

PubMed

Barbour, Michele E; Maddocks, Sarah E; Grady, Helena J; Roper, James A; Bass, Mark D; Collins, Andrew M; Dommett, Rachel M; Saunders, Margaret

2016-08-01

In this study, chlorhexidine hexametaphosphate (CHX-HMP) is investigated as a persistent antimicrobial coating for wound care materials. CHX-HMP was used as a wound care material coating and compared with chlorhexidine digluconate materials with respect to antimicrobial efficacy, toxicity and wound closure. Antimicrobial efficacy at day 1, 3 and 7 was observed with experimental and commercial materials. CHX-HMP coated materials had less toxic effect on human placental cells than commercial chlorhexidine dressings. CHX-HMP in pluronic gel did not delay healing but reduced wound colonization by E. faecalis. CHX-HMP could become a useful component of wound care materials with sustained antimicrobial efficacy, lower toxicity than chlorhexidine digluconate materials, and reduction in wound colonization without affecting closure.

Food Packaging Materials

NASA Technical Reports Server (NTRS)

1978-01-01

The photos show a few of the food products packaged in Alure, a metallized plastic material developed and manufactured by St. Regis Paper Company's Flexible Packaging Division, Dallas, Texas. The material incorporates a metallized film originally developed for space applications. Among the suppliers of the film to St. Regis is King-Seeley Thermos Company, Winchester, Ma'ssachusetts. Initially used by NASA as a signal-bouncing reflective coating for the Echo 1 communications satellite, the film was developed by a company later absorbed by King-Seeley. The metallized film was also used as insulating material for components of a number of other spacecraft. St. Regis developed Alure to meet a multiple packaging material need: good eye appeal, product protection for long periods and the ability to be used successfully on a wide variety of food packaging equipment. When the cost of aluminum foil skyrocketed, packagers sought substitute metallized materials but experiments with a number of them uncovered problems; some were too expensive, some did not adequately protect the product, some were difficult for the machinery to handle. Alure offers a solution. St. Regis created Alure by sandwiching the metallized film between layers of plastics. The resulting laminated metallized material has the superior eye appeal of foil but is less expensive and more easily machined. Alure effectively blocks out light, moisture and oxygen and therefore gives the packaged food long shelf life. A major packaging firm conducted its own tests of the material and confirmed the advantages of machinability and shelf life, adding that it runs faster on machines than materials used in the past and it decreases product waste; the net effect is increased productivity.

49 CFR 176.156 - Defective packages.

Code of Federal Regulations, 2010 CFR

2010-10-01

... packages. (a) No leaking, broken, or otherwise defective package containing Class 1 (explosive) materials.... (b) No Class 1 (explosive) material, which for any reason has deteriorated or undergone a change of...

46 CFR 160.052-3a - Materials-Dee ring and snap hook assemblies and other instruments of closure for buoyant vests.

Code of Federal Regulations, 2014 CFR

2014-10-01

... instruments of closure for buoyant vests. 160.052-3a Section 160.052-3a Shipping COAST GUARD, DEPARTMENT OF... LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Plastic Foam, Adult and Child § 160.052-3a Materials—Dee ring and snap hook assemblies and other instruments of closure for buoyant vests. (a...

46 CFR 160.060-3a - Materials-Dee ring and snap hook assemblies and other instruments of closure for buoyant vests.

Code of Federal Regulations, 2011 CFR

2011-10-01

... instruments of closure for buoyant vests. 160.060-3a Section 160.060-3a Shipping COAST GUARD, DEPARTMENT OF... LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Polyethylene Foam, Adult and Child § 160.060-3a Materials—Dee ring and snap hook assemblies and other instruments of closure for buoyant vests...

46 CFR 160.060-3a - Materials-Dee ring and snap hook assemblies and other instruments of closure for buoyant vests.

Code of Federal Regulations, 2013 CFR

2013-10-01

... instruments of closure for buoyant vests. 160.060-3a Section 160.060-3a Shipping COAST GUARD, DEPARTMENT OF... LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Polyethylene Foam, Adult and Child § 160.060-3a Materials—Dee ring and snap hook assemblies and other instruments of closure for buoyant vests...

46 CFR 160.052-3a - Materials-Dee ring and snap hook assemblies and other instruments of closure for buoyant vests.

Code of Federal Regulations, 2013 CFR

2013-10-01

... instruments of closure for buoyant vests. 160.052-3a Section 160.052-3a Shipping COAST GUARD, DEPARTMENT OF... LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Plastic Foam, Adult and Child § 160.052-3a Materials—Dee ring and snap hook assemblies and other instruments of closure for buoyant vests. (a...

46 CFR 160.060-3a - Materials-Dee ring and snap hook assemblies and other instruments of closure for buoyant vests.

Code of Federal Regulations, 2012 CFR

2012-10-01

... instruments of closure for buoyant vests. 160.060-3a Section 160.060-3a Shipping COAST GUARD, DEPARTMENT OF... LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Polyethylene Foam, Adult and Child § 160.060-3a Materials—Dee ring and snap hook assemblies and other instruments of closure for buoyant vests...

46 CFR 160.060-3a - Materials-Dee ring and snap hook assemblies and other instruments of closure for buoyant vests.

Code of Federal Regulations, 2014 CFR

2014-10-01

... instruments of closure for buoyant vests. 160.060-3a Section 160.060-3a Shipping COAST GUARD, DEPARTMENT OF... LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Polyethylene Foam, Adult and Child § 160.060-3a Materials—Dee ring and snap hook assemblies and other instruments of closure for buoyant vests...

46 CFR 160.052-3a - Materials-Dee ring and snap hook assemblies and other instruments of closure for buoyant vests.

Code of Federal Regulations, 2011 CFR

2011-10-01

... instruments of closure for buoyant vests. 160.052-3a Section 160.052-3a Shipping COAST GUARD, DEPARTMENT OF... LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Plastic Foam, Adult and Child § 160.052-3a Materials—Dee ring and snap hook assemblies and other instruments of closure for buoyant vests. (a...

46 CFR 160.052-3a - Materials-Dee ring and snap hook assemblies and other instruments of closure for buoyant vests.

Code of Federal Regulations, 2012 CFR

2012-10-01

... instruments of closure for buoyant vests. 160.052-3a Section 160.052-3a Shipping COAST GUARD, DEPARTMENT OF... LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Plastic Foam, Adult and Child § 160.052-3a Materials—Dee ring and snap hook assemblies and other instruments of closure for buoyant vests. (a...

interThermalPhaseChangeFoam-A framework for two-phase flow simulations with thermally driven phase change

NASA Astrophysics Data System (ADS)

Nabil, Mahdi; Rattner, Alexander S.

The volume-of-fluid (VOF) approach is a mature technique for simulating two-phase flows. However, VOF simulation of phase-change heat transfer is still in its infancy. Multiple closure formulations have been proposed in the literature, each suited to different applications. While these have enabled significant research advances, few implementations are publicly available, actively maintained, or inter-operable. Here, a VOF solver is presented (interThermalPhaseChangeFoam), which incorporates an extensible framework for phase-change heat transfer modeling, enabling simulation of diverse phenomena in a single environment. The solver employs object oriented OpenFOAM library features, including Run-Time-Type-Identification to enable rapid implementation and run-time selection of phase change and surface tension force models. The solver is packaged with multiple phase change and surface tension closure models, adapted and refined from earlier studies. This code has previously been applied to study wavy film condensation, Taylor flow evaporation, nucleate boiling, and dropwise condensation. Tutorial cases are provided for simulation of horizontal film condensation, smooth and wavy falling film condensation, nucleate boiling, and bubble condensation. Validation and grid sensitivity studies, interfacial transport models, effects of spurious currents from surface tension models, effects of artificial heat transfer due to numerical factors, and parallel scaling performance are described in detail in the Supplemental Material (see Appendix A). By incorporating the framework and demonstration cases into a single environment, users can rapidly apply the solver to study phase-change processes of interest.

An experimental-computational analysis of MHV cavitation: effects of leaflet squeezing and rebound.

PubMed

Makhijani, V B; Yang, H Q; Singhal, A K; Hwang, N H

1994-04-01

A combined experimental-computational study was performed to investigate the flow mechanics which could cause cavitation during the squeezing and rebounding phases of valve closure in the 29 mm mitral bileaflet Edwards-Duromedics (ED) mechanical heart valve (MHV). Leaflet closing motion was measured in vitro, and input into a computational fluid mechanics software package, CFD-ACE, to compute flow velocities and pressures in the small gap space between the occluder tip and valve housing. The possibility of cavitation inception was predicted when fluid pressures dropped below the saturated vapor pressure for blood plasma. The computational analysis indicated that cavitation is more likely to be induced during valve rebound rather than the squeezing phase of valve closure in the 29 mm ED-MHV. Also, there is a higher probability of cavitation at lower values of the gap width at the point of impact between the leaflet tip and housing. These predictions of cavitation inception are not likely to be significantly influenced by the water-hammer pressure gradient that develops during valve closure.

ICPP tank farm closure study. Volume 2: Engineering design files

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-02-01

Volume 2 contains the following topical sections: Tank farm heel flushing/pH adjustment; Grouting experiments for immobilization of tank farm heel; Savannah River high level waste tank 20 closure; Tank farm closure information; Clean closure of tank farm; Remediation issues; Remote demolition techniques; Decision concerning EIS for debris treatment facility; CERCLA/RCRA issues; Area of contamination determination; Containment building of debris treatment facility; Double containment issues; Characterization costs; Packaging and disposal options for the waste resulting from the total removal of the tank farm; Take-off calculations for the total removal of soils and structures at the tank farm; Vessel off-gas systems; Jet-groutedmore » polymer and subsurface walls; Exposure calculations for total removal of tank farm; Recommended instrumentation during retrieval operations; High level waste tank concrete encasement evaluation; Recommended heavy equipment and sizing equipment for total removal activities; Tank buoyancy constraints; Grout and concrete formulas for tank heel solidification; Tank heel pH requirements; Tank cooling water; Evaluation of conservatism of vehicle loading on vaults; Typical vault dimensions and approximately tank and vault void volumes; Radiological concerns for temporary vessel off-gas system; Flushing calculations for tank heels; Grout lift depth analysis; Decontamination solution for waste transfer piping; Grout lift determination for filling tank and vault voids; sprung structure vendor data; Grout flow properties through a 2--4 inch pipe; Tank farm load limitations; NRC low level waste grout; Project data sheet calculations; Dose rates for tank farm closure tasks; Exposure and shielding calculations for grout lines; TFF radionuclide release rates; Documentation of the clean closure of a system with listed waste discharge; and Documentation of the ORNL method of radionuclide concentrations in tanks.« less

49 CFR 173.212 - Non-bulk packagings for solid hazardous materials in Packing Group II.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 2 2011-10-01 2011-10-01 false Non-bulk packagings for solid hazardous materials... Hazardous Materials Other Than Class 1 and Class 7 § 173.212 Non-bulk packagings for solid hazardous materials in Packing Group II. (a) When § 172.101 of this subchapter specifies that a solid hazardous...

49 CFR 173.212 - Non-bulk packagings for solid hazardous materials in Packing Group II.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Non-bulk packagings for solid hazardous materials... Hazardous Materials Other Than Class 1 and Class 7 § 173.212 Non-bulk packagings for solid hazardous materials in Packing Group II. (a) When § 172.101 of this subchapter specifies that a solid hazardous...

49 CFR 173.213 - Non-bulk packagings for solid hazardous materials in Packing Group III.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Non-bulk packagings for solid hazardous materials... Hazardous Materials Other Than Class 1 and Class 7 § 173.213 Non-bulk packagings for solid hazardous materials in Packing Group III. (a) When § 172.101 of this subchapter specifies that a solid hazardous...

49 CFR 173.211 - Non-bulk packagings for solid hazardous materials in Packing Group I.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 2 2011-10-01 2011-10-01 false Non-bulk packagings for solid hazardous materials... Hazardous Materials Other Than Class 1 and Class 7 § 173.211 Non-bulk packagings for solid hazardous materials in Packing Group I. (a) When § 172.101 of this subchapter specifies that a solid hazardous...

49 CFR 173.213 - Non-bulk packagings for solid hazardous materials in Packing Group III.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 2 2011-10-01 2011-10-01 false Non-bulk packagings for solid hazardous materials... Hazardous Materials Other Than Class 1 and Class 7 § 173.213 Non-bulk packagings for solid hazardous materials in Packing Group III. (a) When § 172.101 of this subchapter specifies that a solid hazardous...

49 CFR 173.211 - Non-bulk packagings for solid hazardous materials in Packing Group I.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Non-bulk packagings for solid hazardous materials... Hazardous Materials Other Than Class 1 and Class 7 § 173.211 Non-bulk packagings for solid hazardous materials in Packing Group I. (a) When § 172.101 of this subchapter specifies that a solid hazardous...

49 CFR 173.4a - Excepted quantities.

Code of Federal Regulations, 2014 CFR

2014-10-01

... this section; and (3) For gases a water capacity of 30 mL (1.8 cubic inches) or less. (d) Outer... outer packaging must not exceed the limits provided in the following paragraphs. For outer packagings..., rigid outer packaging. (5) Placement of the material in the package or packing different materials in...

49 CFR 173.4a - Excepted quantities.

Code of Federal Regulations, 2013 CFR

2013-10-01

... this section; and (3) For gases a water capacity of 30 mL (1.8 cubic inches) or less. (d) Outer... outer packaging must not exceed the limits provided in the following paragraphs. For outer packagings..., rigid outer packaging. (5) Placement of the material in the package or packing different materials in...

19 CFR 10.539 - Retail packaging materials and containers.

Code of Federal Regulations, 2010 CFR

2010-04-01

...-Singapore Free Trade Agreement Rules of Origin § 10.539 Retail packaging materials and containers. Packaging... requirement. The United States importer of good C decides to use the build-down method, RVC=((AV−VNM)/AV... content requirement. In applying this method, the non-originating blister packages are taken into account...

49 CFR 173.6 - Materials of trade exceptions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... SHIPMENTS AND PACKAGINGS General § 173.6 Materials of trade exceptions. When transported by motor vehicle in... solids, liquids, and sharps, the outer packaging must be a strong, tight packaging securely closed and...) Packagings must be leak tight for liquids and gases, sift proof for solids, and be securely closed, secured...

49 CFR 173.6 - Materials of trade exceptions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SHIPMENTS AND PACKAGINGS General § 173.6 Materials of trade exceptions. When transported by motor vehicle in... solids, liquids, and sharps, the outer packaging must be a strong, tight packaging securely closed and...) Packagings must be leak tight for liquids and gases, sift proof for solids, and be securely closed, secured...

49 CFR 173.6 - Materials of trade exceptions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... SHIPMENTS AND PACKAGINGS General § 173.6 Materials of trade exceptions. When transported by motor vehicle in... outer packaging must be securely closed to prevent leaks or punctures. For solids, liquids, and sharps...) Packaging. (1) Packagings must be leak tight for liquids and gases, sift proof for solids, and be securely...

49 CFR 173.6 - Materials of trade exceptions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... SHIPMENTS AND PACKAGINGS General § 173.6 Materials of trade exceptions. When transported by motor vehicle in... solids, liquids, and sharps, the outer packaging must be a strong, tight packaging securely closed and...) Packagings must be leak tight for liquids and gases, sift proof for solids, and be securely closed, secured...

A Thermodynamics Course Package in Onenote

ERIC Educational Resources Information Center

Falconer, John L.; Nicodemus, Garret D.; Medlin, J. Will; deGrazia, Janet; McDanel, Katherine P.

2014-01-01

A ready-to-use package of active-learning materials for a semester-long chemical engineering thermodynamics course was prepared for instructors, and similar materials are being prepared for a material and energy balance course. The course package includes ConcepTests, explanations of the ConcepTests for instructors, links to screencasts, chapter…

21 CFR 109.15 - Use of polychlorinated biphenyls (PCB's) in establishments manufacturing food-packaging materials.

Code of Federal Regulations, 2010 CFR

2010-04-01

... establishments manufacturing food-packaging materials. 109.15 Section 109.15 Food and Drugs FOOD AND DRUG... polychlorinated biphenyls (PCB's) in establishments manufacturing food-packaging materials. (a) Polychlorinated...). These accidents in turn caused the contamination of food products intended for human consumption (meat...

21 CFR 509.15 - Use of polychlorinated biphenyls (PCB's) in establishments manufacturing food-packaging materials.

Code of Federal Regulations, 2010 CFR

2010-04-01

... establishments manufacturing food-packaging materials. 509.15 Section 509.15 Food and Drugs FOOD AND DRUG... polychlorinated biphenyls (PCB's) in establishments manufacturing food-packaging materials. (a) Polychlorinated...). These accidents in turn caused the contamination of food products intended for human consumption (meat...

14 CFR 135.23 - Manual contents.

Code of Federal Regulations, 2011 CFR

2011-01-01

... packages that are marked or labeled as containing hazardous materials or that show signs of containing... packages that do not conform to the Hazardous Materials Regulations in 49 CFR parts 171 through 180 or that... information to ensure the following: (A) That packages containing hazardous materials are properly offered and...

Green and biodegradable composite films with novel antimicrobial performance based on cellulose.

PubMed

Wu, Yuehan; Luo, Xiaogang; Li, Wei; Song, Rong; Li, Jing; Li, Yan; Li, Bin; Liu, Shilin

2016-04-15

In order to obtain a safe and biodegradable material with antimicrobial properties from cellulose for food packaging, we presented a facile way to graft chitosan onto the oxidized cellulose films. The obtained films had a high transparent property of above 80% transmittance, excellent barrier properties against oxygen and antimicrobial properties against Escherichia coli and Staphylococcus aureus. The antimicrobial properties, mechanical properties, and water vapor permeability of composites are essential characteristics in determining their applicability as food-packaging materials. Moreover, using a sausage model, it was shown that the composites exhibited better performance than traditional polyethylene packaging material and demonstrated good potential as food packaging materials. The results presented a new insight into the development of green materials for food packaging. Copyright © 2015 Elsevier Ltd. All rights reserved.

Profiling of metal ions leached from pharmaceutical packaging materials.

PubMed

Fliszar, Kyle A; Walker, David; Allain, Leonardo

2006-01-01

Metal leachables from packaging components can affect the safety and efficacy of a pharmaceutical formulation. As liquid formulations continue to contain surfactants, salts, and chelating agents coupled with lower drug levels, the interaction between the formulation and the packaging material becomes more important. This study examines the interaction of commonly used packaging materials with extraction solvents representative of liquid formulations found in the pharmaceutical industry stressed under conditions encountered during accelerated stability studies.

Vacuum decay container/closure integrity testing technology. Part 1. ASTM F2338-09 precision and bias studies.

PubMed

Wolf, Heinz; Stauffer, Tony; Chen, Shu-Chen Y; Lee, Yoojin; Forster, Ronald; Ludzinski, Miron; Kamat, Madhav; Godorov, Phillip; Guazzo, Dana Morton

2009-01-01

ASTM F2338-09 Standard Test Method for Nondestructive Detection of Leaks in Packages by Vacuum Decay Method is applicable for leak-testing rigid and semi-rigid non-lidded trays; trays or cups sealed with porous barrier lidding materials; rigid, nonporous packages; and flexible, nonporous packages. Part 1 of this series describes the precision and bias studies performed in 2008 to expand this method's scope to include rigid, nonporous packages completely or partially filled with liquid. Round robin tests using three VeriPac 325/LV vacuum decay leak testers (Packaging Technologies & Inspection, LLC, Tuckahoe, NY) were performed at three test sites. Test packages were 1-mL glass syringes. Positive controls had laser-drilled holes in the barrel ranging from about 5 to 15 microm in nominal diameter. Two different leak tests methods were performed at each site: a "gas leak test" performed at 250 mbar (absolute) and a "liquid leak test" performed at about 1 mbar (absolute). The gas leak test was used to test empty, air-filled syringes. All defects with holes > or = 5.0 microm and all no-defect controls were correctly identified. The only false negative result was attributed to a single syringe with a < 5.0-microm hole. Tests performed using a calibrated air leak supported a 0.10-cm3 x min(-1) (ccm) sensitivity limit (99/99 lower tolerance limit). The liquid leak test was used to test both empty, air-filled syringes and water-filled syringes. Test results were 100% accurate for all empty and water-filled syringes, both without holes and with holes (5, 10, and 15 microm). Tests performed using calibrated air flow leaks of 0, 0.05, and 0.10 ccm were also 100% accurate; data supported a 0.10-ccm sensitivity limit (99/99 lower tolerance limit). Quantitative differential pressure results strongly correlated to hole size using either liquid or gas vacuum decay leak tests. The higher vacuum liquid leak test gave noticeably higher pressure readings when water was present in the defect. Both the ASTM F2338-09 test method and the precision and bias study report are available by contacting ASTM International in West Conshohocken, PA, USA (www.astm.org).

Influence of factors on release of antimicrobials from antimicrobial packaging materials.

PubMed

Wu, Yu-Mei; Wang, Zhi-Wei; Hu, Chang-Ying; Nerín, Cristina

2018-05-03

Antimicrobial packaging materials (films or coatings) (APMs) have aroused great interest among the scientists or the experts specialized in material science, food science, packaging engineering, biology and chemistry. APMs have been used to package the food, such as dairy products, poultry, meat (e.g., beef), salmon muscle, pastry dough, fresh pasta, bakery products, fruits, vegetables and beverages. Some materials have been already commercialized. The ability of APMs to extend the shelf-life of the food depends on the release rate of the antimicrobials (AMs) from the materials to the food. The optimum rate is defined as target release rate (TRR). To achieve TRR, the influencing factors of the release rate should be considered. Herein we reviewed for the first time these factors and their influence on the release. These factors mainly include the AMs, food (or food simulant), packaging materials, the interactions among them, the temperature and environmental relative humidity (RH).

Antimicrobial agent-free hybrid cationic starch/sodium alginate polyelectrolyte films for food packaging materials.

PubMed

Şen, Ferhat; Uzunsoy, İrem; Baştürk, Emre; Kahraman, Memet Vezir

2017-08-15

This study aimed to develop polyelectrolyte structured antimicrobial food packaging materials that do not contain any antimicrobial agents. Cationic starch was synthesized and characterized by FT-IR spectroscopy and 1 H NMR spectroscopy. Its nitrogen content was determined by Kjeldahl method. Polyelectrolyte structured antimicrobial food packaging materials were prepared using starch, cationic starch and sodium alginate. Antimicrobial activity of materials was defined by inhibition zone method (disc diffusion method). Thermal stability of samples was evaluated by TGA and DSC. Hydrophobicity of samples was determined by contact angle measurements. Surface morphology of samples was investigated by SEM. Moreover, gel contents of samples were determined. The obtained results prove that produced food packaging materials have good thermal, antimicrobial and surface properties, and they can be used as food packaging material in many industries. Copyright © 2017 Elsevier Ltd. All rights reserved.

Examination of SR101 shipping packages

DOE Office of Scientific and Technical Information (OSTI.GOV)

Daugherty, W. L.

Four SR101 shipping packages were removed from service and provided for disassembly and examination of the internal fiberboard assemblies. These packages were 20 years old, and had experienced varying levels of degradation. Two of the packages were successfully disassembled and fiberboard samples were removed from these packages and tested. Mechanical and thermal property values are generally comparable to or higher than baseline values measured on fiberboard from 9975 packages, which differs primarily in the specified density range. While baseline data for the SR101 material is not available, this comparison with 9975 material suggests that the material properties of the SR101more » fiberboard have not significantly degraded.« less

77 FR 40385 - Withdrawal of Regulatory Guide 7.3; Procedures for Picking Up and Receiving Packages of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-09

... Picking Up and Receiving Packages of Radioactive Material AGENCY: Nuclear Regulatory Commission. ACTION... Receiving Packages of Radioactive Material.'' The RG is being withdrawn because it is outdated and the..., ``Administrative Guide for Verifying Compliance with Packaging Requirements for Shipment and Receipt of Radioactive...

49 CFR 171.1 - Applicability of Hazardous Materials Regulations (HMR) to persons and functions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... transportation of hazardous materials in commerce and to pre-transportation and transportation functions. (a..., reconditions, repairs, or tests a packaging or a component of a packaging that is represented, marked..., reconditions, repairs, or tests a packaging or a component of a packaging that is represented, marked...

46 CFR 160.047-3a - Materials-Dee ring and snap hook assemblies and other instruments of closure for buoyant vests.

Code of Federal Regulations, 2014 CFR

2014-10-01

... instruments of closure for buoyant vests. 160.047-3a Section 160.047-3a Shipping COAST GUARD, DEPARTMENT OF... LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Kapok or Fibrous Glass, Adult and Child § 160.047-3a Materials—Dee ring and snap hook assemblies and other instruments of closure for buoyant vests. (a...

46 CFR 160.047-3a - Materials-Dee ring and snap hook assemblies and other instruments of closure for buoyant vests.

Code of Federal Regulations, 2012 CFR

2012-10-01

... instruments of closure for buoyant vests. 160.047-3a Section 160.047-3a Shipping COAST GUARD, DEPARTMENT OF... LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Kapok or Fibrous Glass, Adult and Child § 160.047-3a Materials—Dee ring and snap hook assemblies and other instruments of closure for buoyant vests. (a...

46 CFR 160.047-3a - Materials-Dee ring and snap hook assemblies and other instruments of closure for buoyant vests.

Code of Federal Regulations, 2011 CFR

2011-10-01

... instruments of closure for buoyant vests. 160.047-3a Section 160.047-3a Shipping COAST GUARD, DEPARTMENT OF... LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Kapok or Fibrous Glass, Adult and Child § 160.047-3a Materials—Dee ring and snap hook assemblies and other instruments of closure for buoyant vests. (a...

46 CFR 160.047-3a - Materials-Dee ring and snap hook assemblies and other instruments of closure for buoyant vests.

Code of Federal Regulations, 2013 CFR

2013-10-01

... instruments of closure for buoyant vests. 160.047-3a Section 160.047-3a Shipping COAST GUARD, DEPARTMENT OF... LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Kapok or Fibrous Glass, Adult and Child § 160.047-3a Materials—Dee ring and snap hook assemblies and other instruments of closure for buoyant vests. (a...

48 CFR 552.211-89 - Non-manufactured wood packaging material for export.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Non-manufactured wood... and Clauses 552.211-89 Non-manufactured wood packaging material for export. As prescribed in 511.204(b)(4), insert the following clause: Non-Manufactured Wood Packaging Material for Export (JAN 2010) (a...

48 CFR 552.211-89 - Non-manufactured wood packaging material for export.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Non-manufactured wood... and Clauses 552.211-89 Non-manufactured wood packaging material for export. As prescribed in 511.204(b)(4), insert the following clause: Non-Manufactured Wood Packaging Material for Export (JAN 2010) (a...

48 CFR 552.211-89 - Non-manufactured wood packaging material for export.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Non-manufactured wood... and Clauses 552.211-89 Non-manufactured wood packaging material for export. As prescribed in 511.204(b)(4), insert the following clause: Non-Manufactured Wood Packaging Material for Export (JAN 2010) (a...

19 CFR 10.601 - Retail packaging materials and containers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 1 2012-04-01 2012-04-01 false Retail packaging materials and containers. 10.601...-Central America-United States Free Trade Agreement Rules of Origin § 10.601 Retail packaging materials and... for retail sale, if classified with the good for which preferential tariff treatment under the CAFTA...

19 CFR 10.601 - Retail packaging materials and containers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 1 2014-04-01 2014-04-01 false Retail packaging materials and containers. 10.601...-Central America-United States Free Trade Agreement Rules of Origin § 10.601 Retail packaging materials and... for retail sale, if classified with the good for which preferential tariff treatment under the CAFTA...

19 CFR 10.601 - Retail packaging materials and containers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 1 2011-04-01 2011-04-01 false Retail packaging materials and containers. 10.601...-Central America-United States Free Trade Agreement Rules of Origin § 10.601 Retail packaging materials and... for retail sale, if classified with the good for which preferential tariff treatment under the CAFTA...

19 CFR 10.601 - Retail packaging materials and containers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Retail packaging materials and containers. 10.601...-Central America-United States Free Trade Agreement Rules of Origin § 10.601 Retail packaging materials and... for retail sale, if classified with the good for which preferential tariff treatment under the CAFTA...

48 CFR 552.211-89 - Non-manufactured wood packaging material for export.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Non-manufactured wood... and Clauses 552.211-89 Non-manufactured wood packaging material for export. As prescribed in 511.204(b)(4), insert the following clause: Non-Manufactured Wood Packaging Material for Export (JAN 2010) (a...

48 CFR 552.211-89 - Non-manufactured wood packaging material for export.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Non-manufactured wood... and Clauses 552.211-89 Non-manufactured wood packaging material for export. As prescribed in 511.204(b)(4), insert the following clause: Non-Manufactured Wood Packaging Material for Export (JAN 2010) (a...

21 CFR 179.45 - Packaging materials for use during the irradiation of prepackaged foods.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Packaging materials for use during the irradiation... OF HEALTH AND HUMAN SERVICES (CONTINUED) IRRADIATION IN THE PRODUCTION, PROCESSING AND HANDLING OF... irradiation of prepackaged foods. The packaging materials identified in this section may be safely subjected...

49 CFR 173.224 - Packaging and control and emergency temperatures for self-reactive materials.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 2 2014-10-01 2014-10-01 false Packaging and control and emergency temperatures... temperatures for self-reactive materials. (a) General. When the § 172.101 table of this subchapter specifies... packagings meeting Packing Group I are not authorized. Self-reactive materials which require temperature...

49 CFR 173.224 - Packaging and control and emergency temperatures for self-reactive materials.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Packaging and control and emergency temperatures... temperatures for self-reactive materials. (a) General. When the § 172.101 table of this subchapter specifies... packagings meeting Packing Group I are not authorized. Self-reactive materials which require temperature...

49 CFR 173.224 - Packaging and control and emergency temperatures for self-reactive materials.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 2 2011-10-01 2011-10-01 false Packaging and control and emergency temperatures... temperatures for self-reactive materials. (a) General. When the § 172.101 table of this subchapter specifies... packagings meeting Packing Group I are not authorized. Self-reactive materials which require temperature...

49 CFR 173.224 - Packaging and control and emergency temperatures for self-reactive materials.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 2 2012-10-01 2012-10-01 false Packaging and control and emergency temperatures... temperatures for self-reactive materials. (a) General. When the § 172.101 table of this subchapter specifies... packagings meeting Packing Group I are not authorized. Self-reactive materials which require temperature...

49 CFR 173.224 - Packaging and control and emergency temperatures for self-reactive materials.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 2 2013-10-01 2013-10-01 false Packaging and control and emergency temperatures... temperatures for self-reactive materials. (a) General. When the § 172.101 table of this subchapter specifies... packagings meeting Packing Group I are not authorized. Self-reactive materials which require temperature...

Stability of flavoured phytosterol-enriched drinking yogurts during storage as affected by different packaging materials.

PubMed

Semeniuc, Cristina Anamaria; Cardenia, Vladimiro; Mandrioli, Mara; Muste, Sevastiţa; Borsari, Andrea; Rodriguez-Estrada, Maria Teresa

2016-06-01

The aim of this study was to investigate the influence of different packaging materials on storage stability of flavoured phytosterol-enriched drinking yogurts. White vanilla (WV) and blood orange (BO) phytosterol-enriched drinking yogurts conditioned in mono-layer and triple-layer co-extruded plastic bottles were stored at +6 ± 1 °C for 35 days (under alternating 12 h light and 12 h darkness) to simulate shelf-life conditions. Samples were collected at three different storage times and subjected to determination of total sterol content (TSC), peroxide value (PV) and thiobarbituric acid reactive substances (TBARs). TSC was not significantly affected by packaging material or storage time and met the quantity declared on the label. PV was significantly influenced by yogurt type × packaging material × storage time interaction and TBARs by packaging material × storage time interaction. Between the two packaging materials, the triple-layer plastic mini bottle with black coloured and completely opaque intermediate layer offered the best protection against lipid oxidation. © 2015 Society of Chemical Industry. © 2015 Society of Chemical Industry.

Packaging and Transportation Safety

DOT National Transportation Integrated Search

1997-01-31

This Guide supplements the Department of Energy (DOE) Order, DOE O 460.1A, PACKAGING AND TRANSPORTATION SAFETY, 10-2-96, by providing clarifying material for the implementation of packaging and transportation safety of hazardous materials. DOE O 460....

Recent advances in biopolymers and biopolymer-based nanocomposites for food packaging materials.

PubMed

Tang, X Z; Kumar, P; Alavi, S; Sandeep, K P

2012-01-01

Plastic packaging for food and non-food applications is non-biodegradable, and also uses up valuable and scarce non-renewable resources like petroleum. With the current focus on exploring alternatives to petroleum and emphasis on reduced environmental impact, research is increasingly being directed at development of biodegradable food packaging from biopolymer-based materials. The proposed paper will present a review of recent developments in biopolymer-based food packaging materials including natural biopolymers (such as starches and proteins), synthetic biopolymers (such as poly lactic acid), biopolymer blends, and nanocomposites based on natural and synthetic biopolymers. The paper will discuss the various techniques that have been used for developing cost-effective biodegradable packaging materials with optimum mechanical strength and oxygen and moisture barrier properties. This is a timely review as there has been a recent renewed interest in research studies, both in the industry and academia, towards development of a new generation of biopolymer-based food packaging materials with possible applications in other areas.

Safety analysis report for packaging (onsite) steel drum

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCormick, W.A.

This Safety Analysis Report for Packaging (SARP) provides the analyses and evaluations necessary to demonstrate that the steel drum packaging system meets the transportation safety requirements of HNF-PRO-154, Responsibilities and Procedures for all Hazardous Material Shipments, for an onsite packaging containing Type B quantities of solid and liquid radioactive materials. The basic component of the steel drum packaging system is the 208 L (55-gal) steel drum.

LEVERAGING AGING MATERIALS DATA TO SUPPORT EXTENSION OF TRANSPORTATION SHIPPING PACKAGES SERVICE LIFE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dunn, K.; Bellamy, S.; Daugherty, W.

Nuclear material inventories are increasingly being transferred to interim storage locations where they may reside for extended periods of time. Use of a shipping package to store nuclear materials after the transfer has become more common for a variety of reasons. Shipping packages are robust and have a qualified pedigree for performance in normal operation and accident conditions but are only certified over an approved transportation window. The continued use of shipping packages to contain nuclear material during interim storage will result in reduced overall costs and reduced exposure to workers. However, the shipping package materials of construction must maintainmore » integrity as specified by the safety basis of the storage facility throughout the storage period, which is typically well beyond the certified transportation window. In many ways, the certification processes required for interim storage of nuclear materials in shipping packages is similar to life extension programs required for dry cask storage systems for commercial nuclear fuels. The storage of spent nuclear fuel in dry cask storage systems is federally-regulated, and over 1500 individual dry casks have been in successful service up to 20 years in the US. The uncertainty in final disposition will likely require extended storage of this fuel well beyond initial license periods and perhaps multiple re-licenses may be needed. Thus, both the shipping packages and the dry cask storage systems require materials integrity assessments and assurance of continued satisfactory materials performance over times not considered in the original evaluation processes. Test programs for the shipping packages have been established to obtain aging data on materials of construction to demonstrate continued system integrity. The collective data may be coupled with similar data for the dry cask storage systems and used to support extending the service life of shipping packages in both transportation and storage.« less

Summary of Uranium Solubility Studies in Concrete Waste Forms and Vadose Zone Environments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Golovich, Elizabeth C.; Wellman, Dawn M.; Serne, R. Jeffrey

2011-09-30

One of the methods being considered for safely disposing of Category 3 low-level radioactive wastes is to encase the waste in concrete. Concrete encasement would contain and isolate the waste packages from the hydrologic environment and act as an intrusion barrier. The current plan for waste isolation consists of stacking low-level waste packages on a trench floor, surrounding the stacks with reinforced steel, and encasing these packages in concrete. These concrete-encased waste stacks are expected to vary in size with maximum dimensions of 6.4 m long, 2.7 m wide, and 4 m high. The waste stacks are expected to havemore » a surrounding minimum thickness of 15 cm of concrete encasement. These concrete-encased waste packages are expected to withstand environmental exposure (solar radiation, temperature variations, and precipitation) until an interim soil cover or permanent closure cover is installed and to remain largely intact thereafter. Any failure of concrete encasement may result in water intrusion and consequent mobilization of radionuclides from the waste packages. This report presents the results of investigations elucidating the uranium mineral phases controlling the long-term fate of uranium within concrete waste forms and the solubility of these phases in concrete pore waters and alkaline, circum-neutral vadose zone environments.« less

Base Realignment and Closure (BRAC) Cleanup Plan for Fort Devens, Fort Devens, Massachusetts

DTIC Science & Technology

1994-04-07

Landfill (AOCs 4, 5, 18, and 40) were identified in the MEP as the highest priority (Priority 1A) for remediation. As such, these sites proceeded...Spring Brook Landfills OUs, etc. 4.1.4 Environmental Restoration Early Actions Strategy The Site Investigation (SI) Data Package concept was developed...Approach for the Shepley’ s Hill and Cold Spring Brook Landfill Sites . Fort Devens. Massachusetts, prepared for USAEC; February. Ecology & Environment

A Randomized Effectiveness Trial of a Systems Level Approach to Stepped Care for War Related PTSD

DTIC Science & Technology

2015-09-01

treatment options, STEPS UP includes web- based cognitive behavioral self- management, telephone cognitive-behavioral therapy , continuous RN nurse...IRB closure report packages for the Ft. Campbell and Ft. Stewart sites because study activities are no longer physically occurring at the study sites...significantly associated with decreased physical symptom burden (as measured by the PHQ-15), improved mental health functioning (as measured by the SF

10 CFR 960.5-1 - System guidelines.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REPOSITORY Preclosure Guidelines § 960.5-1 System guidelines. (a) Qualifying conditions—(1) Preclosure... radioactive materials to restricted and unrestricted areas during repository operation and closure shall meet... repository siting, construction, operation, closure, and decommissioning the public and the environment shall...

Hydrothermal carbonization of food waste and associated packaging materials for energy source generation.

PubMed

Li, Liang; Diederick, Ryan; Flora, Joseph R V; Berge, Nicole D

2013-11-01

Hydrothermal carbonization (HTC) is a thermal conversion technique that converts food wastes and associated packaging materials to a valuable, energy-rich resource. Food waste collected from local restaurants was carbonized over time at different temperatures (225, 250 and 275°C) and solids concentrations to determine how process conditions influence carbonization product properties and composition. Experiments were also conducted to determine the influence of packaging material on food waste carbonization. Results indicate the majority of initial carbon remains integrated within the solid-phase at the solids concentrations and reaction temperatures evaluated. Initial solids concentration influences carbon distribution because of increased compound solubilization, while changes in reaction temperature imparted little change on carbon distribution. The presence of packaging materials significantly influences the energy content of the recovered solids. As the proportion of packaging materials increase, the energy content of recovered solids decreases because of the low energetic retention associated with the packaging materials. HTC results in net positive energy balances at all conditions, except at a 5% (dry wt.) solids concentration. Carbonization of food waste and associated packaging materials also results in net positive balances, but energy needs for solids post-processing are significant. Advantages associated with carbonization are not fully realized when only evaluating process energetics. A more detailed life cycle assessment is needed for a more complete comparison of processes. Copyright © 2013 Elsevier Ltd. All rights reserved.

21 CFR 181.22 - Certain substances employed in the manufacture of food-packaging materials.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Certain substances employed in the manufacture of food-packaging materials. 181.22 Section 181.22 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT... Food Ingredients § 181.22 Certain substances employed in the manufacture of food-packaging materials...

78 FR 60726 - Hazardous Materials Regulations: Penalty Guidelines

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-02

..., Radioactive Materials, Compressed Gases in cylinders; Packaging Manufacturers, Drum Manufacturers and... Administrative practices and procedure, Hazardous materials transportation, Packaging and containers, Penalties... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Part...

7 CFR 58.211 - Packaging room for bulk products.

Code of Federal Regulations, 2013 CFR

2013-01-01

... maintained to keep roofs and outside areas free of dry product. Only packaging materials that are used within a day's operation may be kept in the packaging area. These materials shall be kept on metal racks or...

7 CFR 58.211 - Packaging room for bulk products.

Code of Federal Regulations, 2014 CFR

2014-01-01

... maintained to keep roofs and outside areas free of dry product. Only packaging materials that are used within a day's operation may be kept in the packaging area. These materials shall be kept on metal racks or...

7 CFR 58.211 - Packaging room for bulk products.

Code of Federal Regulations, 2011 CFR

2011-01-01

... maintained to keep roofs and outside areas free of dry product. Only packaging materials that are used within a day's operation may be kept in the packaging area. These materials shall be kept on metal racks or...

7 CFR 58.211 - Packaging room for bulk products.

Code of Federal Regulations, 2012 CFR

2012-01-01

... maintained to keep roofs and outside areas free of dry product. Only packaging materials that are used within a day's operation may be kept in the packaging area. These materials shall be kept on metal racks or...

REMOVAL OF LEGACY PLUTONIUM MATERIALS FROM SWEDEN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dunn, Kerry A.; Bellamy, J. Steve; Chandler, Greg T.

2013-08-18

U.S. Department of Energy’s National Nuclear Security Administration (NNSA) Office of Global Threat Reduction (GTRI) recently removed legacy plutonium materials from Sweden in collaboration with AB SVAFO, Sweden. This paper details the activities undertaken through the U.S. receiving site (Savannah River Site (SRS)) to support the characterization, stabilization, packaging and removal of legacy plutonium materials from Sweden in 2012. This effort was undertaken as part of GTRI’s Gap Materials Program and culminated with the successful removal of plutonium from Sweden as announced at the 2012 Nuclear Security Summit. The removal and shipment of plutonium materials to the United States wasmore » the first of its kind under NNSA’s Global Threat Reduction Initiative. The Environmental Assessment for the U.S. receipt of gap plutonium material was approved in May 2010. Since then, the multi-year process yielded many first time accomplishments associated with plutonium packaging and transport activities including the application of the of DOE-STD-3013 stabilization requirements to treat plutonium materials outside the U.S., the development of an acceptance criteria for receipt of plutonium from a foreign country, the development and application of a versatile process flow sheet for the packaging of legacy plutonium materials, the identification of a plutonium container configuration, the first international certificate validation of the 9975 shipping package and the first intercontinental shipment using the 9975 shipping package. This paper will detail the technical considerations in developing the packaging process flow sheet, defining the key elements of the flow sheet and its implementation, determining the criteria used in the selection of the transport package, developing the technical basis for the package certificate amendment and the reviews with multiple licensing authorities and most importantly integrating the technical activities with the Swedish partners.« less

Leaflet Area as a Determinant of Tricuspid Regurgitation Severity in Patients with Pulmonary Hypertension

PubMed Central

Afilalo, Jonathan; Grapsa, Julia; Nihoyannopoulos, Petros; Beaudoin, Jonathan; Gibbs, J. Simon R.; Channick, Richard N.; Langleben, David; Rudski, Lawrence G.; Hua, Lanqi; Handschumacher, Mark D.; Picard, Michael H.; Levine, Robert A.

2015-01-01

Background Tricuspid regurgitation (TR) is a risk factor for mortality in pulmonary hypertension (PH). TR severity varies among patients with comparable degrees of PH and right ventricular (RV) remodeling. The contribution of leaflet adaptation to the pathophysiology of TR has yet to be examined. We hypothesized that tricuspid leaflet area (TLA) is increased in PH, and that its size relative to RV remodeling determines TR severity. Methods and Results A prospective cohort of 255 patients with PH from pre- and post-capillary etiologies was assembled from two centers. Patients underwent a 3-D echocardiogram focused on the tricuspid apparatus. TLA was measured with the Omni custom software package. Compared with normal controls, PH patients had a twofold increase in RV volumes, 62% increase in annulus area, and 49% increase in TLA. Those with severe TR demonstrated inadequate increase in TLA relative to the closure area, such that the ratio of TLA-to-closure area <1.78 was highly predictive of severe TR (odds ratio 68.7; 95% CI 16.2, 292.7). The median vena contracta width was 8.5 mm in the group with small TLA and large closure area as opposed to 4.8 mm in the group with large TLA and large closure area. Conclusions TLA plays a significant role in determining which patients with PH develop severe functional TR. The ratio of TLA-to-closure area, reflecting the balance between leaflet adaptation vs. annular dilation and tethering forces, is an indicator of TR severity that may identify which patients stand to benefit from leaflet augmentation during tricuspid valve repair. PMID:25977303

Contamination in food from packaging material.

PubMed

Lau, O W; Wong, S K

2000-06-16

Packaging has become an indispensible element in the food manufacturing process, and different types of additives, such as antioxidants, stabilizers, lubricants, anti-static and anti-blocking agents, have also been developed to improve the performance of polymeric packaging materials. Recently the packaging has been found to represent a source of contamination itself through the migration of substances from the packaging into food. Various analytical methods have been developed to analyze the migrants in the foodstuff, and migration evaluation procedures based on theoretical prediction of migration from plastic food contact material were also introduced recently. In this paper, the regulatory control, analytical methodology, factors affecting the migration and migration evaluation are reviewed.

Summary of Group Development and Testing for Single Shell Tank Closure at Hanford

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harbour, John, R.

2005-04-28

This report is a summary of the bench-scale and large scale experimental studies performed by Savannah River National Laboratory for CH2M HILL to develop grout design mixes for possible use in producing fill materials as a part of Tank Closure of the Single-Shell Tanks at Hanford. The grout development data provided in this report demonstrates that these design mixes will produce fill materials that are ready for use in Hanford single shell tank closure. The purpose of this report is to assess the ability of the proposed grout specifications to meet the current requirements for successful single shell tank closuremore » which will include the contracting of services for construction and operation of a grout batch plant. The research and field experience gained by SRNL in the closure of Tanks 17F and 20F at the Savannah River Site was leveraged into the grout development efforts for Hanford. It is concluded that the three Hanford grout design mixes provide fill materials that meet the current requirements for successful placement. This conclusion is based on the completion of recommended testing using Hanford area materials by the operators of the grout batch plant. This report summarizes the regulatory drivers and the requirements for grout mixes as tank fill material. It is these requirements for both fresh and cured grout properties that drove the development of the grout formulations for the stabilization, structural and capping layers.« less

Packaging strategies for printed circuit board components. Volume I, materials & thermal stresses.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neilsen, Michael K.; Austin, Kevin N.; Adolf, Douglas Brian

2011-09-01

Decisions on material selections for electronics packaging can be quite complicated by the need to balance the criteria to withstand severe impacts yet survive deep thermal cycles intact. Many times, material choices are based on historical precedence perhaps ignorant of whether those initial choices were carefully investigated or whether the requirements on the new component match those of previous units. The goal of this program focuses on developing both increased intuition for generic packaging guidelines and computational methodologies for optimizing packaging in specific components. Initial efforts centered on characterization of classes of materials common to packaging strategies and computational analysesmore » of stresses generated during thermal cycling to identify strengths and weaknesses of various material choices. Future studies will analyze the same example problems incorporating the effects of curing stresses as needed and analyzing dynamic loadings to compare trends with the quasi-static conclusions.« less

49 CFR 195.124 - Closures.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 3 2013-10-01 2013-10-01 false Closures. 195.124 Section 195.124 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Design Requirements § 195.124...

49 CFR 195.124 - Closures.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 3 2012-10-01 2012-10-01 false Closures. 195.124 Section 195.124 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Design Requirements § 195.124...

49 CFR 195.124 - Closures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Closures. 195.124 Section 195.124 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Design Requirements § 195.124...

49 CFR 195.124 - Closures.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 3 2011-10-01 2011-10-01 false Closures. 195.124 Section 195.124 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Design Requirements § 195.124...

49 CFR 195.124 - Closures.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 3 2014-10-01 2014-10-01 false Closures. 195.124 Section 195.124 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Design Requirements § 195.124...

49 CFR 173.226 - Materials poisonous by inhalation, Division 6.1, Packing Group I, Hazard Zone A.

Code of Federal Regulations, 2011 CFR

2011-10-01

...; (3) Have screw-type closures that are— (i) Closed and tightened to a torque prescribed by the closure manufacturer, using a properly calibrated device that is capable of measuring torque; (ii) Physically held in...

49 CFR 173.226 - Materials poisonous by inhalation, Division 6.1, Packing Group I, Hazard Zone A.

Code of Federal Regulations, 2012 CFR

2012-10-01

...; (3) Have screw-type closures that are— (i) Closed and tightened to a torque prescribed by the closure manufacturer, using a properly calibrated device that is capable of measuring torque; (ii) Physically held in...

49 CFR 173.226 - Materials poisonous by inhalation, Division 6.1, Packing Group I, Hazard Zone A.

Code of Federal Regulations, 2013 CFR

2013-10-01

...; (3) Have screw-type closures that are— (i) Closed and tightened to a torque prescribed by the closure manufacturer, using a properly calibrated device that is capable of measuring torque; (ii) Physically held in...

49 CFR 173.226 - Materials poisonous by inhalation, Division 6.1, Packing Group I, Hazard Zone A.

Code of Federal Regulations, 2010 CFR

2010-10-01

...; (3) Have screw-type closures that are— (i) Closed and tightened to a torque prescribed by the closure manufacturer, using a properly calibrated device that is capable of measuring torque; (ii) Physically held in...

49 CFR 173.226 - Materials poisonous by inhalation, Division 6.1, Packing Group I, Hazard Zone A.

Code of Federal Regulations, 2014 CFR

2014-10-01

...; (3) Have screw-type closures that are— (i) Closed and tightened to a torque prescribed by the closure manufacturer, using a properly calibrated device that is capable of measuring torque; (ii) Physically held in...

7 CFR 319.40-1 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... issued a specific permit. Humus, compost, and litter. Partially or wholly decayed plant matter. Import... materials; humus; compost; and litter. Regulated wood packaging material. Wood packaging material other than...

7 CFR 319.40-1 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... issued a specific permit. Humus, compost, and litter. Partially or wholly decayed plant matter. Import... materials; humus; compost; and litter. Regulated wood packaging material. Wood packaging material other than...

7 CFR 319.40-1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... issued a specific permit. Humus, compost, and litter. Partially or wholly decayed plant matter. Import... materials; humus; compost; and litter. Regulated wood packaging material. Wood packaging material other than...

Assessment of Quality Assurance Measures for Radioactive Material Transport Packages not Requiring Competent Authority Design Approval - 13282

DOE Office of Scientific and Technical Information (OSTI.GOV)

Komann, Steffen; Groeke, Carsten; Droste, Bernhard

The majority of transports of radioactive materials are carried out in packages which don't need a package design approval by a competent authority. Low-active radioactive materials are transported in such packages e.g. in the medical and pharmaceutical industry and in the nuclear industry as well. Decommissioning of NPP's leads to a strong demand for packages to transport low and middle active radioactive waste. According to IAEA regulations the 'non-competent authority approved package types' are the Excepted Packages and the Industrial Packages of Type IP-1, IP-2 and IP-3 and packages of Type A. For these types of packages an assessment bymore » the competent authority is required for the quality assurance measures for the design, manufacture, testing, documentation, use, maintenance and inspection (IAEA SSR 6, Chap. 306). In general a compliance audit of the manufacturer of the packaging is required during this assessment procedure. Their regulatory level in the IAEA regulations is not comparable with the 'regulatory density' for packages requiring competent authority package design approval. Practices in different countries lead to different approaches within the assessment of the quality assurance measures in the management system as well as in the quality assurance program of a special package design. To use the package or packaging in a safe manner and in compliance with the regulations a management system for each phase of the life of the package or packaging is necessary. The relevant IAEA-SSR6 chap. 801 requires documentary verification by the consignor concerning package compliance with the requirements. (authors)« less

Definition of Small Gram Quantity Contents for Type B Radioactive Material Transportation Packages: Activity-Based Content Limitations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sitaraman, S; Kim, S; Biswas, D

2010-10-27

Since the 1960's, the Department of Transportation Specification (DOT Spec) 6M packages have been used extensively for transportation of Type B quantities of radioactive materials between Department of Energy (DOE) facilities, laboratories, and productions sites. However, due to the advancement of packaging technology, the aging of the 6M packages, and variability in the quality of the packages, the DOT implemented a phased elimination of the 6M specification packages (and other DOT Spec packages) in favor of packages certified to meet federal performance requirements. DOT issued the final rule in the Federal Register on October 1, 2004 requiring that use ofmore » the DOT Specification 6M be discontinued as of October 1, 2008. A main driver for the change was the fact that the 6M specification packagings were not supported by a Safety Analysis Report for Packaging (SARP) that was compliant with Title 10 of the Code of Federal Regulations part 71 (10 CFR 71). Therefore, materials that would have historically been shipped in 6M packages are being identified as contents in Type B (and sometimes Type A fissile) package applications and addenda that are to be certified under the requirements of 10 CFR 71. The requirements in 10 CFR 71 include that the Safety Analysis Report for Packaging (SARP) must identify the maximum radioactivity of radioactive constituents and maximum quantities of fissile constituents (10 CFR 71.33(b)(1) and 10 CFR 71.33(b)(2)), and that the application (i.e., SARP submittal or SARP addendum) demonstrates that the external dose rate (due to the maximum radioactivity of radioactive constituents and maximum quantities of fissile constituents) on the surface of the packaging (i.e., package and contents) not exceed 200 mrem/hr (10 CFR 71.35(a), 10 CFR 71.47(a)). It has been proposed that a 'Small Gram Quantity' of radioactive material be defined, such that, when loaded in a transportation package, the dose rates at external points of an unshielded packaging not exceed the regulatory limits prescribed by 10 CFR 71 for non-exclusive shipments. The mass of each radioisotope presented in this paper is limited by the radiation dose rate on the external surface of the package, which per the regulatory limit should not exceed 200 mrem/hr. The results presented are a compendium of allowable masses of a variety of different isotopes (with varying impurity levels of beryllium in some of the actinide isotopes) that, when loaded in an unshielded packaging, do not result in an external dose rate on the surface of the package that exceeds 190 mrem/hr (190 mrem/hr was chosen to provide 5% conservatism relative to the regulatory limit). These mass limits define the term 'Small Gram Quantity' (SGQ) contents in the context of radioactive material transportation packages. The term SGQ is isotope-specific and pertains to contents in radioactive material transportation packages that do not require shielding and still satisfy the external dose rate requirements. Since these calculated mass limits are for contents without shielding, they are conservative for packaging materials that provide some limited shielding or if the contents are placed into a shielded package. The isotopes presented in this paper were chosen as the isotopes that Department of Energy (DOE) sites most likely need to ship. Other more rarely shipped isotopes, along with industrial and medical isotopes, are planned to be included in subsequent extensions of this work.« less

21 CFR 570.13 - Indirect food additives resulting from packaging materials prior sanctioned for animal feed and...

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Indirect food additives resulting from packaging materials prior sanctioned for animal feed and pet food. 570.13 Section 570.13 Food and Drugs FOOD AND DRUG... FOOD ADDITIVES General Provisions § 570.13 Indirect food additives resulting from packaging materials...

21 CFR 570.13 - Indirect food additives resulting from packaging materials prior sanctioned for animal feed and...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Indirect food additives resulting from packaging materials prior sanctioned for animal feed and pet food. 570.13 Section 570.13 Food and Drugs FOOD AND DRUG... FOOD ADDITIVES General Provisions § 570.13 Indirect food additives resulting from packaging materials...

21 CFR 570.13 - Indirect food additives resulting from packaging materials prior sanctioned for animal feed and...

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Indirect food additives resulting from packaging materials prior sanctioned for animal feed and pet food. 570.13 Section 570.13 Food and Drugs FOOD AND DRUG... FOOD ADDITIVES General Provisions § 570.13 Indirect food additives resulting from packaging materials...

21 CFR 570.13 - Indirect food additives resulting from packaging materials prior sanctioned for animal feed and...

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Indirect food additives resulting from packaging materials prior sanctioned for animal feed and pet food. 570.13 Section 570.13 Food and Drugs FOOD AND DRUG... FOOD ADDITIVES General Provisions § 570.13 Indirect food additives resulting from packaging materials...

21 CFR 570.13 - Indirect food additives resulting from packaging materials prior sanctioned for animal feed and...

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Indirect food additives resulting from packaging materials prior sanctioned for animal feed and pet food. 570.13 Section 570.13 Food and Drugs FOOD AND DRUG... FOOD ADDITIVES General Provisions § 570.13 Indirect food additives resulting from packaging materials...

Nanocellulose in green food packaging.

PubMed

Vilarinho, Fernanda; Sanches Silva, Ana; Vaz, M Fátima; Farinha, José Paulo

2018-06-13

The development of packaging materials with new functionalities and lower environmental impact is now an urgent need of our society. On one hand, the shelf-life extension of packaged products can be an answer to the exponential increase of worldwide demand for food. On the other hand, uncertainty of crude oil prices and reserves has imposed the necessity to find raw materials to replace oil-derived polymers. Additionally, consumers' awareness toward environmental issues increasingly pushes industries to look with renewed interest to "green" solutions. In response to these issues, numerous polymers have been exploited to develop biodegradable food packaging materials. Although the use of biopolymers has been limited due to their poor mechanical and barrier properties, these can be enhanced by adding reinforcing nanosized components to form nanocomposites. Cellulose is probably the most used and well-known renewable and sustainable raw material. The mechanical properties, reinforcing capabilities, abundance, low density, and biodegradability of nanosized cellulose make it an ideal candidate for polymer nanocomposites processing. Here we review the potential applications of cellulose based nanocomposites in food packaging materials, highlighting the several types of biopolymers with nanocellulose fillers that have been used to form bio-nanocomposite materials. The trends in nanocellulose packaging applications are also addressed.

Proppant flowback control additives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nguyen, P.D.; Weaver, J.D.; Parker, M.A.

1996-12-31

This paper describes the laboratory and field development of thermoplastic film materials used to reduce proppant flowback that can occur after fracturing treatments. The paper provides a summary of flowback mechanism theories and laboratory tests comparing flowback tendency for various types of treating procedures and materials. Some of these materials include angular proppant, proppant/fiber mixtures, and proppant with film strips tested over a wide range of temperature, closure stress, and flow-rate conditions. Field treatment procedures are discussed, and several case histories are presented. All of the methods evaluated were effective in reducing proppant flowback under certain conditions. Heat-shrink film cutmore » into thin slivers proved to provide flowback reduction over broad temperature and closure stress ranges and was found to cause little impairment to fracture conductivity with some dependency on use concentration, temperature, and closure stress. The film materials were more resistant to damage caused by blending and pumping than all other materials evaluated. In addition, proppant packs, including consolidated packs, were significantly more tolerant of large, repeated stress changes. Field results indicate that the use of the heat-shrink film material as a flowback control agent permits more aggressive bean-up procedures following conventional fracturing treatments. Conventional dry-additive metering systems were used to add the film material to the fracturing fluid proppant slurry.« less

Fracture mechanics analyses of partial crack closure in shell structures

NASA Astrophysics Data System (ADS)

Zhao, Jun

2007-12-01

This thesis presents the theoretical and finite element analyses of crack-face closure behavior in shells and its effect on the stress intensity factor under a bending load condition. Various shell geometries, such as spherical shell, cylindrical shell containing an axial crack, cylindrical shell containing a circumferential crack and shell with double curvatures, are all studied. In addition, the influence of material orthotropy on the crack closure effect in shells is also considered. The theoretical formulation is developed based on the shallow shell theory of Delale and Erdogan, incorporating the effect of crack-face closure at the compressive edges. The line-contact assumption, simulating the crack-face closure at the compressive edges, is employed so that the contact force at the closure edges is introduced, which can be translated to the mid-plane of the shell, accompanied by an additional distributed bending moment. The unknown contact force is computed by solving a mixed-boundary value problem iteratively, that is, along the crack length, either the normal displacement of the crack face at the compressive edges is equal to zero or the contact pressure is equal to zero. It is found that due to the curvature effects crack closure may not always occur on the entire length of the crack, depending on the direction of the bending load and the geometry of the shell. The crack-face closure influences significantly the magnitude of the stress intensity factors; it increases the membrane component but decreases the bending component. The maximum stress intensity factor is reduced by the crack-face closure. The significant influence of geometry and material orthotropy on rack closure behavior in shells is also predicted based on the analytical solutions. Three-dimensional FEA is performed to validate the theoretical solutions. It demonstrates that the crack face closure occurs actually over an area, not on a line, but the theoretical solutions of the stress intensity factor and the FEA solutions are in good agreement, because the contact area is very small compared with the shell thickness.

Biosynthesis and Characterization of AgNPs–Silk/PVA Film for Potential Packaging Application

PubMed Central

Tao, Gang; Cai, Rui; Wang, Yejing; Song, Kai; Guo, Pengchao; Zhao, Ping; Zuo, Hua; He, Huawei

2017-01-01

Bionanocomposite packaging materials have a bright future for a broad range of applications in the food and biomedical industries. Antimicrobial packaging is one of the bionanocomposite packaging materials. Silver nanoparticle (AgNP) is one of the most attractive antimicrobial agents for its broad spectrum of antimicrobial activity against microorganisms. However, the traditional method of preparing AgNPs-functionalized packaging material is cumbersome and not environmentally friendly. To develop an efficient and convenient biosynthesis method to prepare AgNPs-modified bionanocomposite material for packaging applications, we synthesized AgNPs in situ in a silk fibroin solution via the reduction of Ag+ by the tyrosine residue of fibroin, and then prepared AgNPs–silk/poly(vinyl alcohol) (PVA) composite film by blending with PVA. AgNPs were synthesized evenly on the surface or embedded in the interior of silk/PVA film. The prepared AgNPs–silk/PVA film exhibited excellent mechanical performance and stability, as well as good antibacterial activity against both Gram-negative and Gram-positive bacteria. AgNPs–silk/PVA film offers more choices to be potentially applied in the active packaging field. PMID:28773026

Biosynthesis and Characterization of AgNPs-Silk/PVA Film for Potential Packaging Application.

PubMed

Tao, Gang; Cai, Rui; Wang, Yejing; Song, Kai; Guo, Pengchao; Zhao, Ping; Zuo, Hua; He, Huawei

2017-06-17

Bionanocomposite packaging materials have a bright future for a broad range of applications in the food and biomedical industries. Antimicrobial packaging is one of the bionanocomposite packaging materials. Silver nanoparticle (AgNP) is one of the most attractive antimicrobial agents for its broad spectrum of antimicrobial activity against microorganisms. However, the traditional method of preparing AgNPs-functionalized packaging material is cumbersome and not environmentally friendly. To develop an efficient and convenient biosynthesis method to prepare AgNPs-modified bionanocomposite material for packaging applications, we synthesized AgNPs in situ in a silk fibroin solution via the reduction of Ag⁺ by the tyrosine residue of fibroin, and then prepared AgNPs-silk/poly(vinyl alcohol) (PVA) composite film by blending with PVA. AgNPs were synthesized evenly on the surface or embedded in the interior of silk/PVA film. The prepared AgNPs-silk/PVA film exhibited excellent mechanical performance and stability, as well as good antibacterial activity against both Gram-negative and Gram-positive bacteria. AgNPs-silk/PVA film offers more choices to be potentially applied in the active packaging field.

75 FR 53593 - Hazardous Materials: Minor Editorial Corrections and Clarifications

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-01

... transportation, Packaging and containers, Radioactive materials, Reporting and recordkeeping requirements... section specifies general requirements for packaging hazardous materials for transportation by aircraft... contamination on motor vehicles used to transport Class 7 radioactive materials under exclusive use conditions...

[A Contrivance for Closure and Dressing of Orocutaneous Fistula Developed in Advanced Oral Cancer].

PubMed

Nariai, Yoshiki; Akutsu, Junichi; Okuma, Satoe; Odawara, Sho; Kanno, Takahiro; Sekine, Joji

2017-11-01

Orocutaneous fistula sometimes occurs in locallyadvanced unresectable or recurrent oral squamous cell carcinoma. The developed orocutaneous fistula results in constant leakage of saliva, ingested foods and liquids and decline in patients' quality of life(QOL). A 47-year-old Japanese man had received treatment for tongue carcinoma. At the routine follow-up, a cystic lesion in the right submandibular region was detected. Biopsyof the specimen of the cystic lesion revealed squamous cell carcinoma. After chemotherapy, an orocutaneous fistula between the right oropharyngeal and the right submandibular region developed and graduallyincreased. Although closure and dressing of the orocutaneous fistula with various materials was attempted, it was ultimatelyunsuccessful. Finally, application of a rubber film and silicone adhesive agent to the skin was successful for closure and dressing of the fistula. Orocutaneous fistula is one of major contributors to decline in patients' QOL. The sharing of information regarding effective methods or materials for closure and dressing of orocutaneous fistula is necessaryto maintain patients' QOL.

Numeric analysis of terahertz wave propagation in familiar packaging materials

NASA Astrophysics Data System (ADS)

Zhang, Lihong; Yang, Guang

2015-10-01

To assess the potential application of terahertz waves in security examination, the transmission characteristics of terahertz waves in packaging materials should be studied. This paper simulates the propagation of terahertz waves in cloth and paper, studies the changes of shape and position of crest of terahertz waves before and after these materials, and gets the law of these changes, which has potential applications in thickness measurement for the thin insulated materials; gives reflected and transmitted wave of terahertz waves, and computes reflected and transmitted coefficient, indicates the good transmission properties of these materials for terahertz waves, which provides the theoretical basis for the realization of contactless security examination of packaged post, package and people pass the important passageway (such as airport and station).

Hazardous Material Packaging and Transportation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hypes, Philip A.

2016-02-04

This is a student training course. Some course objectives are to: recognize and use standard international and US customary units to describe activities and exposure rates associated with radioactive material; determine whether a quantity of a single radionuclide meets the definition of a class 7 (radioactive) material; determine, for a given single radionuclide, the shipping quantity activity limits per 49 Code of Federal Regulations (CFR) 173.435; determine the appropriate radioactive material hazard class proper shipping name for a given material; determine when a single radionuclide meets the DOT definition of a hazardous substance; determine the appropriate packaging required for amore » given radioactive material; identify the markings to be placed on a package of radioactive material; determine the label(s) to apply to a given radioactive material package; identify the entry requirements for radioactive material labels; determine the proper placement for radioactive material label(s); identify the shipping paper entry requirements for radioactive material; select the appropriate placards for a given radioactive material shipment or vehicle load; and identify allowable transport limits and unacceptable transport conditions for radioactive material.« less

Transformation of food packaging from passive to innovative via nanotechnology: concepts and critiques.

PubMed

Mlalila, Nichrous; Kadam, Dattatreya M; Swai, Hulda; Hilonga, Askwar

2016-09-01

In recent decades, there is a global advancement in manufacturing industry due to increased applications of nanotechnology. Food industry also has been tremendously changing from passive packaging to innovative packaging, to cope with global trends, technological advancements, and consumer preferences. Active research is taking place in food industry and other scientific fields to develop innovative packages including smart, intelligent and active food packaging for more effective and efficient packaging materials with balanced environmental issues. However, in food industry the features behind smart packaging are narrowly defined to be distinguished from intelligent packaging as in other scientific fields, where smart materials are under critical investigations. This review presents some scientific concepts and features pertaining innovative food packaging. The review opens new research window in innovative food packaging to cover the existing disparities for further precise research and development of food packaging industry.

Flexible Foam Protection Materials for Constellation Space Suit Element Portable Life Support Subsystem Packaging Study

NASA Technical Reports Server (NTRS)

Tang, Henry H.; Orndoff, Evelyne S.; Thomas, Gretchen A.

2009-01-01

This paper discusses the effort in evaluating and selecting a light weight impact protection material for the Constellation Space Suit Element (CSSE) Portable Life Support Subsystem (PLSS) conceptual packaging study. A light weight material capable of holding and protecting the components inside the PLSS is required to demonstrate the viability of the flexible PLSS packaging concept. The material needs to distribute, dissipate, and absorb the impact energy of the PLSS falling on the lunar surface. It must also be very robust and function in the extreme lunar thermal vacuum environment for up to one hundred Extravehicular Activity (EVA) missions. This paper documents the performance requirements for selecting a foam protection material, and the methodologies for evaluating commercial off-the-shelf (COTS) foam protection materials. It also presents the materials properties test results and impact drop test results of the various foam materials evaluated in the study. The findings from this study suggest that a foam based flexible protection system is a viable solution for PLSS packaging. However, additional works are needed to optimize COTS foam properties or to develop a composite foam system that will meet all the performance requirements for the CSSE PLSS flexible packaging.

Active and intelligent packaging systems for a modern society.

PubMed

Realini, Carolina E; Marcos, Begonya

2014-11-01

Active and intelligent packaging systems are continuously evolving in response to growing challenges from a modern society. This article reviews: (1) the different categories of active and intelligent packaging concepts and currently available commercial applications, (2) latest packaging research trends and innovations, and (3) the growth perspectives of the active and intelligent packaging market. Active packaging aiming at extending shelf life or improving safety while maintaining quality is progressing towards the incorporation of natural active agents into more sustainable packaging materials. Intelligent packaging systems which monitor the condition of the packed food or its environment are progressing towards more cost-effective, convenient and integrated systems to provide innovative packaging solutions. Market growth is expected for active packaging with leading shares for moisture absorbers, oxygen scavengers, microwave susceptors and antimicrobial packaging. The market for intelligent packaging is also promising with strong gains for time-temperature indicator labels and advancements in the integration of intelligent concepts into packaging materials. Copyright © 2014 Elsevier Ltd. All rights reserved.

Three-dimensional measurements of fatigue crack closure

NASA Technical Reports Server (NTRS)

Ray, S. K.; Grandt, A. F., Jr.

1984-01-01

Fatigue crack growth and retardation experiments conducted in polycarbonate test specimen are described. The transparent test material allows optical interferometry measurements of the fatigue crack opening (and closing) profiles. Crack surface displacements are obtained through the specimen thickness and three dimensional aspects of fatigue crack closure are discussed.

Conical O-ring seal

DOEpatents

Chalfant, Jr., Gordon G.

1984-01-01

A shipping container for radioactive or other hazardous materials which has a conical-shaped closure containing grooves in the conical surface thereof and an O-ring seal incorporated in each of such grooves. The closure and seal provide a much stronger, tighter and compact containment than with a conventional flanged joint.

Conical O-ring seal

DOEpatents

Chalfant, G.G. Jr.

A shipping container for radioactive or other hazardous materials has a conical-shaped closure containing grooves in the conical surface thereof and an O-ring seal incorporated in each of such grooves. The closure and seal provide a much stronger, tighter and compact containment than with a conventional flanged joint.

19 CFR 102.15 - Disregarded materials.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 1 2011-04-01 2011-04-01 false Disregarded materials. 102.15 Section 102.15... TREASURY RULES OF ORIGIN Rules of Origin § 102.15 Disregarded materials. (a) The following materials shall...: (1) Packaging materials and containers in which a good is packaged for retail sale that are...

19 CFR 102.15 - Disregarded materials.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 1 2014-04-01 2014-04-01 false Disregarded materials. 102.15 Section 102.15... TREASURY RULES OF ORIGIN Rules of Origin § 102.15 Disregarded materials. (a) The following materials shall...: (1) Packaging materials and containers in which a good is packaged for retail sale that are...

The pharmaceutical vial capping process: Container closure systems, capping equipment, regulatory framework, and seal quality tests.

PubMed

Mathaes, Roman; Mahler, Hanns-Christian; Buettiker, Jean-Pierre; Roehl, Holger; Lam, Philippe; Brown, Helen; Luemkemann, Joerg; Adler, Michael; Huwyler, Joerg; Streubel, Alexander; Mohl, Silke

2016-02-01

Parenteral drug products are protected by appropriate primary packaging to protect against environmental factors, including potential microbial contamination during shelf life duration. The most commonly used CCS configuration for parenteral drug products is the glass vial, sealed with a rubber stopper and an aluminum crimp cap. In combination with an adequately designed and controlled aseptic fill/finish processes, a well-designed and characterized capping process is indispensable to ensure product quality and integrity and to minimize rejections during the manufacturing process. In this review, the health authority requirements and expectations related to container closure system quality and container closure integrity are summarized. The pharmaceutical vial, the rubber stopper, and the crimp cap are described. Different capping techniques are critically compared: The most common capping equipment with a rotating capping plate produces the lowest amount of particle. The strength and challenges of methods to control the capping process are discussed. The residual seal force method can characterize the capping process independent of the used capping equipment or CCS. We analyze the root causes of several cosmetic defects associated with the vial capping process. Copyright © 2015 Elsevier B.V. All rights reserved.

49 CFR 173.4a - Excepted quantities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... of withstanding without leakage the pressure differential specified in § 173.27(c) of this part. (b... ice), and lithium batteries and cells. (c) Inner packaging limits. The maximum quantity of hazardous..., rigid outer packaging. (5) Placement of the material in the package or packing different materials in...

Optimizing biomass blends for manufacturing molded packaging materials using mycelium

USDA-ARS?s Scientific Manuscript database

Polystyrene is one of the most widely used plastics and is commonly produced in three forms: 1) Extruded polystyrene – disposable utensils, CD/DVD cases, yogurt containers, smoke alarm housing, etc.; 2) Expanded polystyrene foam – molded packaging materials and packaging "peanuts"; 3) Extruded polys...

Mass Transfer Study of Chlorine Dioxide Gas Through Polymeric Packaging Materials

USDA-ARS?s Scientific Manuscript database

A continuous system for measuring the mass transfer of gaseous chlorine dioxide (ClO2), a strong oxidizing agent and used in food and pharmaceutical packaging, through 10 different types of polymeric packaging material was developed utilizing electrochemical sensor as a detector. Permeability, diff...

49 CFR 178.609 - Test requirements for packagings for infectious substances.

Code of Federal Regulations, 2010 CFR

2010-10-01

... paragraph (c), which, for test purposes, categorizes packagings according to their material characteristics... performance may be rapidly affected by moisture; plastics that may embrittle at low temperature; and other... the appropriate test. Table I—Tests Required Material of Outer packaging Fiberboard Plastics Other...

Photo-Curable Metal-Chelating Coatings Offer a Scalable Approach to Production of Antioxidant Active Packaging.

PubMed

Lin, Zhuangsheng; Goddard, Julie

2018-02-01

Synthetic metal chelators (for example, ethylenediaminetetraacetic acid, EDTA) are widely used as additives to control trace transition metal induced oxidation in consumer products. To enable removal of synthetic chelators in response to increasing consumer demand for clean label products, metal-chelating active food packaging technologies have been developed with demonstrated antioxidant efficacy in simulated food systems. However, prior work in fabrication of metal-chelating materials leveraged batch chemical reactions to tether metal-chelating ligands, a process with limited industrial translatability for large-scale fabrication. To improve the industrial translatability, we have designed a 2-step laminated photo-grafting process to introduce metal chelating functionality onto common polymeric packaging materials. Iminodiacetic acid (IDA) functionalized materials were fabricated by photo-grafting poly(acrylic acid) onto polypropylene (PP) films, followed by a second photo-grafting process to graft-polymerize an IDA functionalized vinyl monomer (GMA-IDA). The photo-grafting was conducted under atmospheric conditions and was completed in 2 min. The resulting IDA functionalized metal-chelating material was able to chelate iron and copper, and showed antioxidant efficacy against ascorbic acid degradation, supporting its potential to be used synergistically with natural antioxidants for preservation of food and beverage products. The 2-step photo-grafting process improves the throughput of active packaging coatings, enabling potential roll-to-roll fabrication of metal-chelating active packaging materials for antioxidant food packaging applications. To address consumer and retail demands for "clean label" foods and beverages without a corresponding loss in product quality and shelf life, producers are seeking next generation technologies such as active packaging. In this work, we will report the synthesis of metal-chelating active packaging films, which enable removal of the synthetic additive, ethylenediamine tetraacetic acid. The new synthesis technique improves the throughput of metal-chelating active packaging coatings, enabling potential roll-to-roll fabrication of the materials for antioxidant food packaging applications. © 2018 Institute of Food Technologists®.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Loftin, B.; Abramczyk, G.; Koenig, R.

Radioactive materials are stored in a variety of locations throughout the DOE complex. At the Savannah River Site (SRS), materials are stored within dedicated facilities. Each of those facilities has a documented safety analysis (DSA) that describes accidents that the facility and the materials within it may encounter. Facilities at the SRS are planning on utilizing the certified Model 9977 Shipping Package as a long term storage package and one of these facilities required ballistics testing. Specifically, in order to meet the facility DSA, the radioactive materials (RAM) must be contained within the storage package after impact by a .223more » caliber round. In order to qualify the Model 9977 Shipping Package for storage in this location, the package had to be tested under these conditions. Over the past two years, the Model 9977 Shipping Package has been subjected to a series of ballistics tests. The purpose of the testing was to determine if the 9977 would be suitable for use as a storage package at a Savannah River Site facility. The facility requirements are that the package must not release any of its contents following the impact in its most vulnerable location by a .223 caliber round. A package, assembled to meet all of the design requirements for a certified 9977 shipping configuration and using simulated contents, was tested at the Savannah River Site in March of 2011. The testing was completed and the package was examined. The results of the testing and examination are presented in this paper.« less

Food safety concerns deriving from the use of silver based food packaging materials.

PubMed

Pezzuto, Alessandra; Losasso, Carmen; Mancin, Marzia; Gallocchio, Federica; Piovesana, Alessia; Binato, Giovanni; Gallina, Albino; Marangon, Alberto; Mioni, Renzo; Favretti, Michela; Ricci, Antonia

2015-01-01

The formulation of innovative packaging solutions, exerting a functional antimicrobial role in slowing down food spoilage, is expected to have a significant impact on the food industry, allowing both the maintenance of food safety criteria for longer periods and the reduction of food waste. Different materials are considered able to exert the required antimicrobial activity, among which are materials containing silver. However, challenges exist in the application of silver to food contact materials due to knowledge gaps in the production of ingredients, stability of delivery systems in food matrices and health risks caused by the same properties which also offer the benefits. Aims of the present study were to test the effectiveness and suitability of two packaging systems, one of which contained silver, for packaging and storing Stracchino cheese, a typical Italian fresh cheese, and to investigate if there was any potential for consumers to be exposed to silver, via migration from the packaging to the cheese. Results did not show any significant difference in the effectiveness of the packaging systems on packaged Stracchino cheese, excluding that the active packaging systems exerted an inhibitory effect on the growth of spoilage microorganisms. Moreover, silver migrated into the cheese matrix throughout the storage time (24 days). Silver levels in cheese finally exceeded the maximum established level for the migration of a non-authorised substance through a functional barrier (Commission of the European Communities, 2009). This result poses safety concerns and strongly suggests the need for more research aimed at better characterizing the new packaging materials in terms of their potential impacts on human health and the environment.

Romanian experience on packaging testing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vieru, G.

2007-07-01

With more than twenty years ago, the Institute for Nuclear Research Pitesti (INR), through its Reliability and Testing Laboratory, was licensed by the Romanian Nuclear Regulatory Body- CNCAN and to carry out qualification tests [1] for packages intended to be used for the transport and storage of radioactive materials. Radioactive materials, generated by Romanian nuclear facilities [2] are packaged in accordance with national [3] and the IAEA's Regulations [1,6] for a safe transport to the disposal center. Subjecting these packages to the normal and simulating test conditions accomplish the evaluation and certification in order to prove the package technical performances.more » The paper describes the qualification tests for type A and B packages used for transport and storage of radioactive materials, during a period of 20 years of experience. Testing is used to substantiate assumption in analytical models and to demonstrate package structural response. The Romanian test facilities [1,3,6] are used to simulate the required qualification tests and have been developed at INR Pitesti, the main supplier of type A packages used for transport and storage of low radioactive wastes in Romania. The testing programme will continue to be a strong option to support future package development, to perform a broad range of verification and certification tests on radioactive material packages or component sections, such as packages used for transport of radioactive sources to be used for industrial or medical purposes [2,8]. The paper describes and contain illustrations showing some of the various tests packages which have been performed during certain periods and how they relate to normal conditions and minor mishaps during transport. Quality assurance and quality controls measures taken in order to meet technical specification provided by the design there are also presented and commented. (authors)« less

Natural additives and agricultural wastes in biopolymer formulations for food packaging.

PubMed

Valdés, Arantzazu; Mellinas, Ana Cristina; Ramos, Marina; Garrigós, María Carmen; Jiménez, Alfonso

2014-01-01

The main directions in food packaging research are targeted toward improvements in food quality and food safety. For this purpose, food packaging providing longer product shelf-life, as well as the monitoring of safety and quality based upon international standards, is desirable. New active packaging strategies represent a key area of development in new multifunctional materials where the use of natural additives and/or agricultural wastes is getting increasing interest. The development of new materials, and particularly innovative biopolymer formulations, can help to address these requirements and also with other packaging functions such as: food protection and preservation, marketing and smart communication to consumers. The use of biocomposites for active food packaging is one of the most studied approaches in the last years on materials in contact with food. Applications of these innovative biocomposites could help to provide new food packaging materials with improved mechanical, barrier, antioxidant, and antimicrobial properties. From the food industry standpoint, concerns such as the safety and risk associated with these new additives, migration properties and possible human ingestion and regulations need to be considered. The latest innovations in the use of these innovative formulations to obtain biocomposites are reported in this review. Legislative issues related to the use of natural additives and agricultural wastes in food packaging systems are also discussed.

Natural additives and agricultural wastes in biopolymer formulations for food packaging

NASA Astrophysics Data System (ADS)

Valdés, Arantzazu; Mellinas, Ana Cristina; Ramos, Marina; Garrigós, María Carmen; Jiménez, Alfonso

2014-02-01

The main directions in food packaging research are targeted towards improvements in food quality and food safety. For this purpose, food packaging providing longer product shelf-life, as well as the monitoring of safety and quality based upon international standards, is desirable. New active packaging strategies represent a key area of development in new multifunctional materials where the use of natural additives and/or agricultural wastes is getting increasing interest. The development of new materials, and particularly innovative biopolymer formulations, can help to address these requirements and also with other packaging functions such as: food protection and preservation, marketing and smart communication to consumers. The use of biocomposites for active food packaging is one of the most studied approaches in the last years on materials in contact with food. Applications of these innovative biocomposites could help to provide new food packaging materials with improved mechanical, barrier, antioxidant and antimicrobial properties. From the food industry standpoint, concerns such as the safety and risk associated with these new additives, migration properties and possible human ingestion and regulations need to be considered. The latest innovations in the use of these innovative formulations to obtain biocomposites are reported in this review. Legislative issues related to the use of natural additives and agricultural wastes in food packaging systems are also discussed.

Natural additives and agricultural wastes in biopolymer formulations for food packaging

PubMed Central

Valdés, Arantzazu; Mellinas, Ana Cristina; Ramos, Marina; Garrigós, María Carmen; Jiménez, Alfonso

2014-01-01

The main directions in food packaging research are targeted toward improvements in food quality and food safety. For this purpose, food packaging providing longer product shelf-life, as well as the monitoring of safety and quality based upon international standards, is desirable. New active packaging strategies represent a key area of development in new multifunctional materials where the use of natural additives and/or agricultural wastes is getting increasing interest. The development of new materials, and particularly innovative biopolymer formulations, can help to address these requirements and also with other packaging functions such as: food protection and preservation, marketing and smart communication to consumers. The use of biocomposites for active food packaging is one of the most studied approaches in the last years on materials in contact with food. Applications of these innovative biocomposites could help to provide new food packaging materials with improved mechanical, barrier, antioxidant, and antimicrobial properties. From the food industry standpoint, concerns such as the safety and risk associated with these new additives, migration properties and possible human ingestion and regulations need to be considered. The latest innovations in the use of these innovative formulations to obtain biocomposites are reported in this review. Legislative issues related to the use of natural additives and agricultural wastes in food packaging systems are also discussed. PMID:24790975

DETERMINATION OF OPTIMAL TOXICANT LOADING FOR BIOLOGICAL CLOSURE OF A HAZARDOUS WASTE SITE

EPA Science Inventory

Information on Phase I and Phase Il of a multitask effort to achieve biological closure of an abandoned hazardous waste site. aste materials, in the form of buried sludges and lagoon wastes, were examined. ptimal loading levels were evaluated on the basis of biodegradative potent...

Advancements in meat packaging.

PubMed

McMillin, Kenneth W

2017-10-01

Packaging of meat provides the same or similar benefits for raw chilled and processed meats as other types of food packaging. Although air-permeable packaging is most prevalent for raw chilled red meat, vacuum and modified atmosphere packaging offer longer shelf life. The major advancements in meat packaging have been in the widely used plastic polymers while biobased materials and their integration into composite packaging are receiving much attention for functionality and sustainability. At this time, active and intelligent packaging are not widely used for antioxidant, antimicrobial, and other functions to stabilize and enhance meat properties although many options are being developed and investigated. The advances being made in nanotechnology will be incorporated into food packaging and presumably into meat packaging when appropriate and useful. Intelligent packaging using sensors for transmission of desired information and prompting of subsequent changes in packaging materials, environments or the products to maintain safety and quality are still in developmental stages. Copyright © 2017 Elsevier Ltd. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, James; Goins, Monty; Paul, Pran

This safety analysis report for packaging (SARP) presents the results of the safety analysis prepared in support of the Consolidated Nuclear Security, LLC (CNS) request for licensing of the Model ES-3100 package with bulk highly enriched uranium (HEU) contents and issuance of a Type B(U) Fissile Material Certificate of Compliance. This SARP, published in the format specified in the Nuclear Regulatory Commission (NRC) Regulatory Guide 7.9 and using information provided in UCID-21218 and NRC Regulatory Guide 7.10, demonstrates that the Y-12 National Security Complex (Y-12) ES-3100 package with bulk HEU contents meets the established NRC regulations for packaging, preparation formore » shipment, and transportation of radioactive materials given in Title 10, Part 71, of the Code of Federal Regulations (CFR) [10 CFR 71] as well as U.S. Department of Transportation (DOT) regulations for packaging and shipment of hazardous materials given in Title 49 CFR. To protect the health and safety of the public, shipments of adioactive materials are made in packaging that is designed, fabricated, assembled, tested, procured, used, maintained, and repaired in accordance with the provisions cited above. Safety requirements addressed by the regulations that must be met when transporting radioactive materials are containment of radioactive materials, radiation shielding, and assurance of nuclear subcriticality.« less

Nutrition. Learning Activity Package.

ERIC Educational Resources Information Center

Lee, Carolyn

This learning activity package on nutrition is one of a series of 12 titles developed for use in health occupations education programs. Materials in the package include objectives, a list of materials needed, a list of definitions, information sheets, reviews (self evaluations) of portions of the content, and answers to reviews. These topics are…

Shock & Anaphylactic Shock. Learning Activity Package.

ERIC Educational Resources Information Center

Hime, Kirsten

This learning activity package on shock and anaphylactic shock is one of a series of 12 titles developed for use in health occupations education programs. Materials in the package include objectives, a list of materials needed, information sheets, reviews (self evaluations) of portions of the content, and answers to reviews. These topics are…

Evaluation of select blends of cotton byproducts in the manufacture of biodegradable packaging material

USDA-ARS?s Scientific Manuscript database

Polystyrene is one of the most widely used plastics in the manufacture of packaging materials. Extruded polystyrene foam is commonly sold under the trademark name of StyrofoamTM. Polystyrene packaging is a multibillion dollar a year industry. Since polystyrene is non-biodegradable, a biodegradable m...

Oral Hygiene. Learning Activity Package.

ERIC Educational Resources Information Center

Hime, Kirsten

This learning activity package on oral hygiene is one of a series of 12 titles developed for use in health occupations education programs. Materials in the package include objectives, a list of materials needed, a list of definitions, information sheets, reviews (self evaluations) of portions of the content, and answers to reviews. These topics…

Grooming. Learning Activity Package.

ERIC Educational Resources Information Center

Stark, Pamela

This learning activity package on grooming for health workers is one of a series of 12 titles developed for use in health occupations education programs. Materials in the package include objectives, a list of materials needed, information sheets, reviews (self evaluations) of portions of the content, and answers to reviews. These topics are…

49 CFR 173.154 - Exceptions for Class 8 (corrosive materials).

Code of Federal Regulations, 2012 CFR

2012-10-01

... solids, packed in a strong outer packaging. (2) For corrosive materials in Packing Group III, inner... capacity each for solids, packed in a strong outer packaging. (c) Consumer commodities. Until December 31... other requirements of this subchapter when transported by motor vehicle or rail car in a packaging...

49 CFR 173.62 - Specific packaging requirements for explosives.

Code of Federal Regulations, 2011 CFR

2011-10-01

... article or material carried in the vehicle; and (ii) The assembled gun packed on the vehicle may not... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS... kg in small packages as specified by the Associate Administrator for Hazardous Materials Safety 110(a...

49 CFR 173.62 - Specific packaging requirements for explosives.

Code of Federal Regulations, 2012 CFR

2012-10-01

... article or material carried in the vehicle; and (ii) The assembled gun packed on the vehicle may not... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS... packages as specified by the Associate Administrator for Hazardous Materials Safety 110(a) Bags Bags Drums...

49 CFR 173.424 - Excepted packages for radioactive instruments and articles.

Code of Federal Regulations, 2011 CFR

2011-10-01

... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS SHIPPERS-GENERAL REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Class 7 (Radioactive) Materials § 173.424....1 mSv/hour (10 mrem/hour); (e) The active material is completely enclosed by non-active components...

49 CFR 173.424 - Excepted packages for radioactive instruments and articles.

Code of Federal Regulations, 2010 CFR

2010-10-01

... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS SHIPPERS-GENERAL REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Class 7 (Radioactive) Materials § 173.424....1 mSv/hour (10 mrem/hour); (e) The active material is completely enclosed by non-active components...

Measurements of True Leak Rates of MEMS Packages

PubMed Central

Han, Bongtae

2012-01-01

Gas transport mechanisms that characterize the hermetic behavior of MEMS packages are fundamentally different depending upon which sealing materials are used in the packages. In metallic seals, gas transport occurs through a few nanoscale leak channels (gas conduction) that are produced randomly during the solder reflow process, while gas transport in polymeric seals occurs through the bulk material (gas diffusion). In this review article, the techniques to measure true leak rates of MEMS packages with the two sealing materials are described and discussed: a Helium mass spectrometer based technique for metallic sealing and a gas diffusion based model for polymeric sealing. PMID:22736994

Prediction of drug-packaging interactions via molecular dynamics (MD) simulations.

PubMed

Feenstra, Peter; Brunsteiner, Michael; Khinast, Johannes

2012-07-15

The interaction between packaging materials and drug products is an important issue for the pharmaceutical industry, since during manufacturing, processing and storage a drug product is continuously exposed to various packaging materials. The experimental investigation of a great variety of different packaging material-drug product combinations in terms of efficacy and safety can be a costly and time-consuming task. In our work we used molecular dynamics (MD) simulations in order to evaluate the applicability of such methods to pre-screening of the packaging material-solute compatibility. The solvation free energy and the free energy of adsorption of diverse solute/solvent/solid systems were estimated. The results of our simulations agree with experimental values previously published in the literature, which indicates that the methods in question can be used to semi-quantitatively reproduce the solid-liquid interactions of the investigated systems. Copyright © 2012 Elsevier B.V. All rights reserved.

Decontamination of food packaging using electron beam—status and prospects

NASA Astrophysics Data System (ADS)

Mittendorfer, J.; Bierbaumer, H. P.; Gratzl, F.; Kellauer, E.

2002-03-01

In this paper the status of food packaging disinfection decontamination using electron beam at Mediscan GmbH is presented. The first section of the paper describes the activities at the service center, where food packaging materials, e.g. yoghurt cups are decontaminated in their final shipment containers. As important step in the hazard analysis and critical control point of food processing, microbiological uncontaminated food packaging material is of public interest and attracts a lot of attention from packaging material producers and food processors. The dose ranges for different sterility assurance levels are discussed and results from microbiological test are presented. Studies at Mediscan have demonstrated, that an electron beam treatment at a dose of 5-7 kGy is most effective against yeast and mold, which are mainly responsible for spoilage and short shelf-life of a variety of products. The second section is devoted to the field of inline decontamination of food packaging and sterilization of pharmaceutical packaging material and the research currently conducted at Mediscan. The requirements for industrial inline electron beam systems are summarized and design concepts discussed in terms of beam energy, beam current, irradiation topology, product handling and shielding.

Flexible Foam Protection Materials for Portable Life Support System Packaging Study

NASA Technical Reports Server (NTRS)

Tang,Henry H.; Dillon, Paul A.; Thomas, Gretchen A.

2009-01-01

This paper discusses the phase I effort in evaluating and selecting a light weight impact protection material for the Constellation Space Suit Element (CSSE) Portable Life Support System (PLSS) conceptual packaging study. A light weight material capable of holding and protecting the components inside the PLSS is required to demonstrate the viability of the flexible PLSS packaging concept. The material needs to distribute, dissipate, and absorb the impact energy of the PLSS falling on the lunar surface. It must also be robust to consistently perform over several Extravehicular Activity (EVA) missions in the extreme lunar thermal vacuum environment. This paper documents the performance requirements for selecting a foam protection material, and the methodologies for evaluating some commercial off-the-shelf (COTS) foam material candidates. It also presents the mechanical properties and impact drop tests results of the foam material candidates. The results of this study suggest that a foam based flexible protection system is a viable solution for PLSS packaging. However, additional works are needed to optimize COTS foam or to develop a composite foam system that will meet all the performance requirements for the CSSE PLSS flexible packaging.

Response of CO2 laser written long period fiber gratings packaged by polymer materials

NASA Astrophysics Data System (ADS)

Wu, Zhaodi; Liu, Yunqi; Zou, Jian; Chen, Na; Pang, Fufei; Wang, Tingyun

2011-12-01

We demonstrate the packaging of CO2 laser written long-period fiber gratings (LPFGs) using different polymer materials. We use three different silicone rubber polymers to package the LPFGs by simply coating it outside the grating. After the polymer coating, the resonance wavelength of LPFG was found to shift towards shorter wavelength by about 6 nm, and the temperature sensitivity of the packaged gratings was studied experimentally. Experiments showed that the gratings packaged by different polymers have different temperature characteristics and all of them have good thermal stability.

Identification of suspected hazardous chemical contaminants in recycled pastry packaging.

PubMed

Ahmadkhaniha, Reza; Rastkari, Noushin

2017-01-01

The safe use of recycled paper and cardboard material for food packaging applications is     an important area of investigation. Therefore, the aim of this study was to determine which hazardous chemi- cal pollutants were found in paper and cardboard samples used for pastry packaging, and to measure the migration of pollutants over time into the pastries. In this study, the presence of some organic pollutants in common confectionery packaging, and the effects of storage time and type of pastry on pollutant migration, were investigated. The results of the study indicate that harmful compounds such as benzophenone, pentachlorophenol, bis(2-ethylhexyl) phthalate and dibutyl phthalate are present at high concentrations in most recycled boxes used for pastry packaging. Since the migration of some of the hazardous compounds from the packaging materials into the pastries under normal conditions was indicated, it is recommended that the procedure for preparing pastry packaging materials should be reconsidered and improved.

Leaflet area as a determinant of tricuspid regurgitation severity in patients with pulmonary hypertension.

PubMed

Afilalo, Jonathan; Grapsa, Julia; Nihoyannopoulos, Petros; Beaudoin, Jonathan; Gibbs, J Simon R; Channick, Richard N; Langleben, David; Rudski, Lawrence G; Hua, Lanqi; Handschumacher, Mark D; Picard, Michael H; Levine, Robert A

2015-05-01

Tricuspid regurgitation (TR) is a risk factor for mortality in pulmonary hypertension (PH). TR severity varies among patients with comparable degrees of PH and right ventricular remodeling. The contribution of leaflet adaptation to the pathophysiology of TR has yet to be examined. We hypothesized that tricuspid leaflet area (TLA) is increased in PH, and that the adequacy of this increase relative to right ventricular remodeling determines TR severity. A prospective cohort of 255 patients with PH from pre and postcapillary pathogeneses was assembled from 2 centers. Patients underwent a 3-dimensional echocardiogram focused on the tricuspid apparatus. TLA was measured with the Omni 4D software package. Compared with normal controls, patients with PH had a 2-fold increase in right ventricular volumes, 62% increase in annular area, and 49% increase in TLA. Those with severe TR demonstrated inadequate increase in TLA relative to the closure area, such that the ratio of TLA:closure area <1.78 was highly predictive of severe TR (odds ratio, 68.7; 95% confidence interval, 16.2-292.7). The median vena contracta width was 8.5 mm in the group with small TLA and large closure area as opposed to 4.8 mm in the group with large TLA and large closure area. TLA plays a significant role in determining which patients with PH develop severe functional TR. The ratio of TLA:closure area, reflecting the balance between leaflet adaptation versus annular dilation and tethering forces, is an indicator of TR severity that may identify which patients stand to benefit from leaflet augmentation during tricuspid valve repair. © 2015 American Heart Association, Inc.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prinja, A. K.

The Karhunen-Loeve stochastic spectral expansion of a random binary mixture of immiscible fluids in planar geometry is used to explore asymptotic limits of radiation transport in such mixtures. Under appropriate scalings of mixing parameters - correlation length, volume fraction, and material cross sections - and employing multiple- scale expansion of the angular flux, previously established atomic mix and diffusion limits are reproduced. When applied to highly contrasting material properties in the small cor- relation length limit, the methodology yields a nonstandard reflective medium transport equation that merits further investigation. Finally, a hybrid closure is proposed that produces both small andmore » large correlation length limits of the closure condition for the material averaged equations.« less

Safety analysis report -- Packages LP-50 tritium package (Packaging of fissile and other radioactive materials)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gates, A.A.; McCarthy, P.G.; Edl, J.W.

1975-05-01

Elemental tritium is shipped at low pressure in a stainless steel container (LP-50) surrounded by an aluminum vessel and Celotex insulation at least 4 in. thick in a steel drum. Each package contains a large quantity (greater than a Type A quantity) of nonfissile material, as defined in AECM 0529. This report provides the details of the safety analysis performed for this type container.

Green Composites Made of Bamboo Fabric and Poly (Lactic) Acid for Packaging Applications—A Review

PubMed Central

Nurul Fazita, M.R.; Jayaraman, Krishnan; Bhattacharyya, Debes; Mohamad Haafiz, M.K.; Saurabh, Chaturbhuj K.; Hussin, M. Hazwan; H.P.S., Abdul Khalil

2016-01-01

Petroleum based thermoplastics are widely used in a range of applications, particularly in packaging. However, their usage has resulted in soaring pollutant emissions. Thus, researchers have been driven to seek environmentally friendly alternative packaging materials which are recyclable as well as biodegradable. Due to the excellent mechanical properties of natural fibres, they have been extensively used to reinforce biopolymers to produce biodegradable composites. A detailed understanding of the properties of such composite materials is vital for assessing their applicability to various products. The present review discusses several functional properties related to packaging applications in order to explore the potential of bamboo fibre fabric-poly (lactic) acid composites for packaging applications. Physical properties, heat deflection temperature, impact resistance, recyclability and biodegradability are important functional properties of packaging materials. In this review, we will also comprehensively discuss the chronological events and applications of natural fibre biopolymer composites. PMID:28773558

Heterogeneous Concurrent Modeling and Design in Java (Volume 2: Ptolemy II Software Architecture)

DTIC Science & Technology

2008-04-01

file (EPS) suitable for inclusion in word processors. The image in figure 7.3 is such an EPS file imported into FrameMaker . At this time, the EPS...can be imported into word processors. This figure was imported into FrameMaker . 152 Ptolemy II Plot Package 7.2.4 Modifying the format You can control...FixToken class 57 FrameMaker 149 full name 4 function closures 59 function dependency 48 FunctionDependency class 48 FunctionToken 122 FunctionToken

The LARSYS Educational Package: Instructor's Notes for Use with the Data 100

NASA Technical Reports Server (NTRS)

Lindenlaub, J. C.; Russell, J. D.

1977-01-01

The LARSYS Educational Package is a set of instructional materials developed to train people to analyze remotely sensed multispectral data using LARSYS, a computer software system. The materials included in this volume have been designed to assist LARSYS instructors as they guide students through the LARSYS Educational Package. All of the materials have been updated from the previous version to reflect the use of a Data 100 Remote Terminal.

SHIPMENT OF TWO DOE-STD-3013 CONTAINERS IN A 9977 TYPE B PACKAGE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abramczyk, G.; Bellamy, S.; Loftin, B.

2011-06-06

The 9977 is a certified Type B Packaging authorized to ship uranium and plutonium in metal and oxide forms. Historically, the standard container for these materials has been the DOE-STD-3013 which was specifically designed for the long term storage of plutonium bearing materials. The Department of Energy has used the 9975 Packaging containing a single 3013 container for the transportation and storage of these materials. In order to reduce container, shipping, and storage costs, the 9977 Packaging is being certified for transportation and storage of two 3013 containers. The challenges and risks of this content and the 9977s ability tomore » meet the Code of Federal Regulations for the transport of these materials are presented.« less

49 CFR 178.350 - Specification 7A; general packaging, Type A.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Specification 7A; general packaging, Type A. 178... FOR PACKAGINGS Specifications for Packagings for Class 7 (Radioactive) Materials § 178.350 Specification 7A; general packaging, Type A. (a) Each packaging must meet all applicable requirements of subpart...

Technical advances for abdominal wall closure after intestinal and multivisceral transplantation.

PubMed

Gerlach, Undine A; Pascher, Andreas

2012-06-01

Abdominal wall closure after intestinal transplantation (ITX) or multivisceral transplantation (MVTX) is challenging because of the loss of abdominal domain and wall elasticity as a result of previous operations and donor-to-recipient weight and height mismatch. We report on abdominal wall closure management in 30 ITX and MVTX recipients. In 60% of patients (n = 18), a primary abdominal closure (PAC) was achieved, in 40% (n = 12) a staged closure (SAC) was necessary. Patients with PAC had undergone less pretransplant operations and required less posttransplant relaparotomies. They were mainly ITX recipients or more abdominal domain because of a longer intestinal remnant. A literature review revealed different strategies to overcome a failed primary closure. They focus on graft reduction or an enlargement of the abdominal domain. The latter includes temporary coverage with prosthetic materials for SAC. Definite abdominal closure is achieved by skin only closure, or by using acellular dermal matrix, rotational flaps, rectus muscle fascia or abdominal wall grafts. Abdominal wall reconstruction after ITX/MVTX is commonly demanded and can be conducted by different strategies. The technique should be easy to use in a timely manner and should prevent abdominal infections, intestinal fistulation, incisional hernias, and wound dehiscence.

Comparative Packaging Study

NASA Technical Reports Server (NTRS)

Perchonok, Michele H.; Oziomek, Thomas V.

2009-01-01

Future long duration manned space flights beyond low earth orbit will require the food system to remain safe, acceptable and nutritious. Development of high barrier food packaging will enable this requirement by preventing the ingress and egress of gases and moisture. New high barrier food packaging materials have been identified through a trade study. Practical application of this packaging material within a shelf life test will allow for better determination of whether this material will allow the food system to meet given requirements after the package has undergone processing. The reason to conduct shelf life testing, using a variety of packaging materials, stems from the need to preserve food used for mission durations of several years. Chemical reactions that take place during longer durations may decrease food quality to a point where crew physical or psychological well-being is compromised. This can result in a reduction or loss of mission success. The rate of chemical reactions, including oxidative rancidity and staling, can be controlled by limiting the reactants, reducing the amount of energy available to drive the reaction, and minimizing the amount of water available. Water not only acts as a media for microbial growth, but also as a reactant and means by which two reactants may come into contact with each other. The objective of this study is to evaluate three packaging materials for potential use in long duration space exploration missions.

Optimization of biomass blends in the manufacture of molded packaging materials produced using fungal mycelium

USDA-ARS?s Scientific Manuscript database

Polystyrene is one of the most widely used plastics and is commonly produced in three forms: 1) Extruded polystyrene – disposable utensils, CD/DVD cases, yogurt containers, smoke alarm housing, etc.; 2) Expanded polystyrene foam – molded packaging materials and packaging "peanuts"; 3) Extruded polys...

10 CFR 835.405 - Receipt of packages containing radioactive material.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Receipt of packages containing radioactive material. 835.405 Section 835.405 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Monitoring of...) Measurements of the radiation levels, if the package contains a Type B quantity (as defined at 10 CFR 71.4) of...

10 CFR 835.405 - Receipt of packages containing radioactive material.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Receipt of packages containing radioactive material. 835.405 Section 835.405 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Monitoring of...) Measurements of the radiation levels, if the package contains a Type B quantity (as defined at 10 CFR 71.4) of...

10 CFR 835.405 - Receipt of packages containing radioactive material.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Receipt of packages containing radioactive material. 835.405 Section 835.405 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Monitoring of...) Measurements of the radiation levels, if the package contains a Type B quantity (as defined at 10 CFR 71.4) of...

10 CFR 835.405 - Receipt of packages containing radioactive material.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Receipt of packages containing radioactive material. 835.405 Section 835.405 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Monitoring of...) Measurements of the radiation levels, if the package contains a Type B quantity (as defined at 10 CFR 71.4) of...

10 CFR 835.405 - Receipt of packages containing radioactive material.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Receipt of packages containing radioactive material. 835.405 Section 835.405 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Monitoring of...) Measurements of the radiation levels, if the package contains a Type B quantity (as defined at 10 CFR 71.4) of...

The Surgical Scrub. Learning Activity Package.

ERIC Educational Resources Information Center

Runge, Lillian

This learning activity package on the surgical scrub is one of a series of 12 titles developed for use in health occupations education programs. Materials in the package include objectives, a list of materials needed, a list of definitions, information sheets, reviews (self evaluations) of portions of the content, and answers to reviews. These…

Material balance and diet in bioregenerative life support systems: connection with coefficient of closure.

PubMed

Manukovsky, N S; Kovalev, V S; Somova, L A; Gurevich, Yu L; Sadovsky, M G

2005-01-01

Bioregenerative life support systems (BLSS) with different coefficients of closure are considered. The 66.2% coefficient of closure achieved in "BIOS-3" facility experiments has been taken as a base value. The increase in coefficient of closure up to 72.6-93.0% is planned due to use of soil-like substrate (SLS) and concentrating of urine. Food values were estimated both in a base variant ("BIOS-3"), and with increases in the coefficient of closure. It is shown that food requirements will be more fully satisfied by internal crop production with an increase in the coefficient of closure of the BLSS. Changes of massflow rates on an 'input-output' and inside BLSS are considered. Equations of synthesis and degradation of organic substances in BLSS were examined using a stoichiometric model. The paper shows that at incomplete closure of BLSS containing SLS there is a problem of nitrogen balancing. To compensate for the removal of nitrogen from the system in urine and feces, it is necessary to introduce food and a nitrogen-containing additive. c2005 COSPAR. Published by Elsevier Ltd. All rights reserved.

Low-dielectric constant insulators for future integrated circuits and packages.

PubMed

Kohl, Paul A

2011-01-01

Future integrated circuits and packages will require extraordinary dielectric materials for interconnects to allow transistor advances to be translated into system-level advances. Exceedingly low-permittivity and low-loss materials are required at every level of the electronic system, from chip-level insulators to packages and printed wiring boards. In this review, the requirements and goals for future insulators are discussed followed by a summary of current state-of-the-art materials and technical approaches. Much work needs to be done for insulating materials and structures to meet future needs.

77 FR 60334 - New Marking Standards for Parcels Containing Hazardous Materials

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-03

... substances, certain patient specimens and certain radioactive materials as noted in section 135 of Mailing... due to its form, quantity, and packaging. Not all hazardous materials permitted to be shipped as a... mailable limited quantity materials that meet USPS quantity limitations and packaging requirements. All...

78 FR 60745 - Hazardous Materials: Minor Editorial Corrections and Clarifications (RRR)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-02

... 173.62 This section provides packaging instructions for Class 1 explosive materials. Paragraph (b) of... requirements for approval of special form Class 7 (radioactive) materials. Paragraph (d) of this section notes... activity of special form Class 7 (radioactive) material permitted in a Type A package equals the maximum...

Effects of self-carbon dioxide-generation material for active packaging on pH, water-holding capacity, meat color, lipid oxidation and microbial growth in beef during cold storage.

PubMed

Lee, Seung-Jae; Lee, Seung Yun; Kim, Gap-Don; Kim, Geun-Bae; Jin, Sang Keun; Hur, Sun Jin

2017-08-01

Active packaging refers to the mixing of additive agents into packaging materials with the purpose of maintaining or extending food product quality and shelf life. The aim of this study was to develop an easy and cheap active packaging for beef. Beef loin samples were divided into three packaging groups (C, ziplock bag packaging; T1, vacuum packaging; T2, active packaging) and stored at 4 °C for 21 days. The water-holding capacity was significantly (P < 0.05) higher in C and T2 than in T1 for up to 7 days of storage. The TBARS value was significantly (P < 0.05) lower in T1 and T2 after 7 days of storage. The counts of some microorganism were significantly (P < 0.05) lower in T1 and T2 after 7 days of storage; the total bacterial count and Escherichia coli count were lowest in T2 at the end of storage. These results indicate that active packaging using self-CO 2 -generation materials can extend the shelf life similarly to that observed with vacuum packaging, and that the active packaging method can improve the quality characteristics of beef during cold storage. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

Bi-level microelectronic device package with an integral window

DOEpatents

Peterson, Kenneth A.; Watson, Robert D.

2004-01-06

A package with an integral window for housing a microelectronic device. The integral window is bonded directly to the package without having a separate layer of adhesive material disposed in-between the window and the package. The device can be a semiconductor chip, CCD chip, CMOS chip, VCSEL chip, laser diode, MEMS device, or IMEMS device. The multilayered package can be formed of a LTCC or HTCC cofired ceramic material, with the integral window being simultaneously joined to the package during LTCC or HTCC processing. The microelectronic device can be flip-chip bonded so that the light-sensitive side is optically accessible through the window. The package has at least two levels of circuits for making electrical interconnections to a pair of microelectronic devices. The result is a compact, low-profile package having an integral window that is hermetically sealed to the package prior to mounting and interconnecting the microelectronic device(s).

Flexible, liquid core light guide with focusing and light shaping attachments

DOEpatents

Wojcik, Randolph Frank; Majewski, Stanislaw; Zorn, Carl John; Kross, Brian

1999-01-01

A liquid light guide system for ultraviolet light is disclosed that has a light shaping arrangement for the emitted light, a stable liquid core and sheath and reliable and effective end closures. The end closures include a metal crimping arrangement that utilizes two layers of deformable materials to prevent cracking of endplugs.

49 CFR 178.707 - Standards for composite IBCs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... materials (i.e., plastic or rubber). (3) A “rigid” inner receptacle is an inner receptacle which retains its general shape when empty without closures in place and without benefit of the outer casing. Any inner... closing is effected by gluing or taping, a water-resistant adhesive must be used. (F) All closures must be...

49 CFR 178.707 - Standards for composite IBCs.

Code of Federal Regulations, 2014 CFR

2014-10-01

... materials (i.e., plastic or rubber). (3) A “rigid” inner receptacle is an inner receptacle which retains its general shape when empty without closures in place and without benefit of the outer casing. Any inner... closing is effected by gluing or taping, a water-resistant adhesive must be used. (F) All closures must be...

49 CFR 178.707 - Standards for composite IBCs.

Code of Federal Regulations, 2012 CFR

2012-10-01

... materials (i.e., plastic or rubber). (3) A “rigid” inner receptacle is an inner receptacle which retains its general shape when empty without closures in place and without benefit of the outer casing. Any inner... closing is effected by gluing or taping, a water-resistant adhesive must be used. (F) All closures must be...

49 CFR 173.23 - Previously authorized packaging.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Previously authorized packaging. 173.23 Section... REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Preparation of Hazardous Materials for Transportation § 173.23 Previously authorized packaging. (a) When the regulations specify a packaging with a specification marking...

Packaging and transportation of radioactive materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1978-01-01

The presentations made at the Symposium on Packaging and Transportation of Radioactive Materials are included. The purpose of the meeting was for the interchange of information on the technology and politics of radioactive material transportation. Separate abstracts were prepared for individual items. (DC)

Packaging material and flexible medical tubing containing thermally exfoliated graphite oxide

NASA Technical Reports Server (NTRS)

Prud'homme, Robert K. (Inventor); Aksay, Ilhan A. (Inventor)

2011-01-01

A packaging material or flexible medical tubing containing a modified graphite oxide material, which is a thermally exfoliated graphite oxide with a surface area of from about 300 m.sup.2/g to 2600 m.sup.2/g.

49 CFR 173.36 - Hazardous materials in Large Packagings.

Code of Federal Regulations, 2013 CFR

2013-10-01

... an inner packaging is constructed of paper or flexible plastic, the inner packaging must be replaced...) The Large Packaging is free from corrosion, contamination, cracks, cuts, or other damage which would...

49 CFR 173.36 - Hazardous materials in Large Packagings.

Code of Federal Regulations, 2014 CFR

2014-10-01

... an inner packaging is constructed of paper or flexible plastic, the inner packaging must be replaced...) The Large Packaging is free from corrosion, contamination, cracks, cuts, or other damage which would...

Comparison of Traditional and Innovative Techniques to Solve Technical Challenges

NASA Technical Reports Server (NTRS)

Perchonok, Michele

2010-01-01

Although NASA has an adequate food system for current missions, research is required to accommodate new requirements for future NASA exploration missions. The Inadequate Food System risk reflects the need to develop requirements and technologies that will enable NASA to provide the crew with a safe, nutritious and acceptable food system while effectively balancing appropriate resources such as mass, volume, and crew time in exploratory missions. As we go deeper into space or spend more time on the International Space Station (ISS), there will be requirements for packaged food to be stored for 3 5 years. New food packaging technologies are needed that have adequate oxygen and water barrier properties to maintain the foods' quality over this extended shelf life. NASA has been unsuccessful in identify packaging materials that meet the necessary requirements when using several traditional routes including literature reviews, workshops, and internal shelf life studies on foods packaged in various packaging materials. Small Business Innovative Research grants were used for accelerating food packaging materials research with limited success. In order to accelerate the process, a theoretical challenge was submitted to InnoCentive resulting in a partial award. A similar food packaging challenge was submitted to Yet2.com and several potential commercial packaging material suppliers were identified that, at least partially, met the requirements. Comparisons and results of these challenges will be discussed.

Effects of load and thermal histories on mechanical behavior of materials; Proceedings of the Symposium, Denver, CO, Feb. 25, 26, 1987

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liaw, P.K.; Nicholas, T.

This volume includes topics on fatigue crack propagation; isothermal and thermal-mechanical fatigue; and microstructure, fracture, and damage. Papers are presented on transients in fatigue crack growth, elevated-temperature fatigue crack propagation, the role of crack closure in crack retardation in P/M and I/M aluminum alloys, the acoustic interrogation of fatigue overload effects, and the effects of frequency and environment on crack growth in Inconel 718. Special attention is given to isothermal fatigue failure mechanisms in low-tin lead-based solder, the stress and strain controlled low-cycle fatigue of Pb-Sn solder for electronic packaging applications, load sequence effects on the deformation of isolated microplasticmore » grains, and thermal fatigue of stainless steel. Other papers are on the influence of thermal aging on the creep crack growth behavior of a Cr-Mo steel, the effect of cyclic loading on the fracture toughness of a modified 4340 steel, and the effects of hot rolling condition and boron microalloying on phase transformation and microstructure in niobium-bearing interstitial free steel.« less

Performance of Nonmigratory Iron Chelating Active Packaging Materials in Viscous Model Food Systems.

PubMed

Roman, Maxine J; Decker, Eric A; Goddard, Julie M

2015-09-01

Many packaged food products undergo quality deterioration due to iron promoted oxidative reactions. Recently, we have developed a nonmigratory iron chelating active packaging material that represents a novel approach to inhibit oxidation of foods while addressing consumer demands for "cleanˮ labels. A challenge to the field of nonmigratory active packaging is ensuring that surface-immobilized active agents retain activity in a true food system despite diffusional limitations. Yet, the relationship between food viscosity and nonmigratory active packaging activity retention has never been characterized. The objective of this study was to investigate the influence of food viscosity on iron chelation by a nonmigratory iron chelating active packaging material. Methyl cellulose was added to aqueous buffered iron solutions to yield model systems with viscosities ranging from ∼1 to ∼10(5)  mPa·s, representing viscosities ranging from beverage to mayonnaise. Iron chelation was quantified by material-bound iron content using colorimetry and inductively coupled plasma-optical emission spectrometry (ICP-OES).  Maximum iron chelation was reached in solutions up to viscosity ∼10(2)  mPa·s. In more viscous solutions (up to ∼10(4)  mPa·s), there was a significant decrease in iron chelating capacity (P < 0.05). However, materials still retained at least 76% iron chelating capacity. Additionally, the influence of different food hydrocolloids on the performance of nonmigratory iron chelating active packaging was characterized. Methyl cellulose and carrageenan did not compete with the material for specific iron chelation (P > 0.05). Materials retained 32% to 45% chelating capacity when in contact with competitively chelating hydrocolloids guar gum, locust bean gum, and xanthan gum. This work demonstrates the potential application of nonmigratory iron chelating active packaging in liquid and semi-liquid foods to allow for the removal of synthetic chelators, while maintaining food quality. © 2015 Institute of Food Technologists®

Legislation, control and research in the Nordic countries on plastics for packaging food.

PubMed

Svensson, K

1994-01-01

The present legislation in the Nordic countries for food contact materials is expressed in general terms and contains few detailed requirements. At present Finland is implementing the EEC legislation, Sweden and Norway will probably do so shortly and Denmark has been a member of the EEC since 1973. Current food legislation in Sweden only covers materials or articles intended to come into contact with foodstuffs during processing or packaging in the food industry or by retailers. It does not apply to food packaging materials purchased for use at home or to household utensils. Upon request, the Toxicology Division at the Swedish National Food Administration (NFA) carries out evaluations of materials intended to come into contact with food. In addition, a voluntary organization--Normpack--is currently operating in Sweden. Normpack consists of manufacturers, dealers and users of food packaging materials, who have agreed to abide by certain common standards. In Norway, the Packaging Convention (Emballasjekonvensjonen--on safety of food packaging material from the health point view) serves a similar purpose. Research in this field is conducted at the National Food Agency of Denmark, The Danish Packaging and Transportation Research Institute (ETi) of the Danish Technological Institute (DTI), the Food Research Laboratory at the Technical Research Centre of Finland, MATFORSK, Norconserv and Statoil in Norway and the NFA, PackForsk and the Swedish Institute for Food Research (SIK) in Sweden. Previous studies have concerned plasticizers in PVC (polyvinyl chloride) cling film, overall migration studies on cling film, specific migration of vinyl chloride, styrene and acrylonitrile and off-flavours.(ABSTRACT TRUNCATED AT 250 WORDS)

Bionanocomposites materials for food packaging applications: Concepts and future outlook.

PubMed

Youssef, Ahmed M; El-Sayed, Samah M

2018-08-01

Bionanocomposites materials open a chance for the usage of novel, high performance, lightweight, and ecofriendly composite materials making them take place the traditional non-biodegradable plastic packaging materials. Biopolymers like polysaccharides such as chitosan (CS), carboxymethyl cellulose (CMC), starch and cellophane could be used to resolve environmental hazards owing to their biodegradability and non-toxicity. In addition these advantages, polysaccharides have some disadvantages for example poor mechanical properties and low resistance to water. Therefore, nanomaterials are used to improve the thermal, mechanical and gas barrier properties without hindering their biodegradable and non-toxic characters. Furthermore, the most favorable nanomaterials are layered silicate nanoclays for example montmorillonite (MMT) and kaolinite, zinc oxide (ZnO-NPs), titanium dioxide (TiO 2 -NPs), and silver nanoparticles (Ag-NPs). In packaging application, the improvement of barrier properties of prepared films against oxygen, carbon dioxide, flavor compounds diffusion through the packaging films. Wide varieties of nanomaterials are suitable to offer smart and/or intelligent properties for food packaging materials, as demonstrated by oxygen scavenging capability, antimicrobial activity, and sign of the level of exposure to various harmful features for instance oxygen levels or insufficient temperatures. The compatibility between nanomaterials and polymers matrix consider the most challenge for the preparation of bionanocomposites as well as getting whole distribution of nanoparticles into the polymer matrix. We keen in this review the development of packaging materials performance and their mechanical, degradability and thermal stability as well as antibacterial activity for utilization of bionanocomposites in different packaging application is considered. Copyright © 2018 Elsevier Ltd. All rights reserved.

Packaging Technologies for 500 C SiC Electronics and Sensors: Challenges in Material Science and Technology

NASA Technical Reports Server (NTRS)

Chen, Liang-Yu; Neudeck, Philip G.; Behelm, Glenn M.; Spry, David J.; Meredith, Roger D.; Hunter, Gary W.

2015-01-01

This paper presents ceramic substrates and thick-film metallization based packaging technologies in development for 500C silicon carbide (SiC) electronics and sensors. Prototype high temperature ceramic chip-level packages and printed circuit boards (PCBs) based on ceramic substrates of aluminum oxide (Al2O3) and aluminum nitride (AlN) have been designed and fabricated. These ceramic substrate-based chip-level packages with gold (Au) thick-film metallization have been electrically characterized at temperatures up to 550C. The 96 alumina packaging system composed of chip-level packages and PCBs has been successfully tested with high temperature SiC discrete transistor devices at 500C for over 10,000 hours. In addition to tests in a laboratory environment, a SiC junction field-effect-transistor (JFET) with a packaging system composed of a 96 alumina chip-level package and an alumina printed circuit board was tested on low earth orbit for eighteen months via a NASA International Space Station experiment. In addition to packaging systems for electronics, a spark-plug type sensor package based on this high temperature interconnection system for high temperature SiC capacitive pressure sensors was also developed and tested. In order to further significantly improve the performance of packaging system for higher packaging density, higher operation frequency, power rating, and even higher temperatures, some fundamental material challenges must be addressed. This presentation will discuss previous development and some of the challenges in material science (technology) to improve high temperature dielectrics for packaging applications.

76 FR 11288 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-01

... Guide, DG-7008, ``Leakage Tests on Packages for Shipment of Radioactive Materials.'' FOR FURTHER... regulatory guide (DG), entitled, ``Leakage Tests on Packages for Shipment of Radioactive Materials'' is... Radioactive and Nonnuclear Hazardous Materials, N14, Subcommittee of the American National Standards Institute...

21 CFR 570.14 - Indirect food additives resulting from packaging materials for animal feed and pet food.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Indirect food additives resulting from packaging..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES General Provisions § 570.14 Indirect food additives resulting from packaging materials for animal feed and...

21 CFR 570.14 - Indirect food additives resulting from packaging materials for animal feed and pet food.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Indirect food additives resulting from packaging..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES General Provisions § 570.14 Indirect food additives resulting from packaging materials for animal feed and...

21 CFR 570.14 - Indirect food additives resulting from packaging materials for animal feed and pet food.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Indirect food additives resulting from packaging..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES General Provisions § 570.14 Indirect food additives resulting from packaging materials for animal feed and...

21 CFR 570.14 - Indirect food additives resulting from packaging materials for animal feed and pet food.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Indirect food additives resulting from packaging..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES General Provisions § 570.14 Indirect food additives resulting from packaging materials for animal feed and...

21 CFR 570.14 - Indirect food additives resulting from packaging materials for animal feed and pet food.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Indirect food additives resulting from packaging..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES General Provisions § 570.14 Indirect food additives resulting from packaging materials for animal feed and...

10 CFR 71.59 - Standards for arrays of fissile material packages.

Code of Federal Regulations, 2011 CFR

2011-01-01

... fissile material package shall derive a number “N” based on all the following conditions being satisfied.... The value of the CSI may be zero provided that an unlimited number of packages are subcritical, such...) of this section. Any CSI greater than zero must be rounded up to the first decimal place. (c) For a...

10 CFR 71.59 - Standards for arrays of fissile material packages.

Code of Federal Regulations, 2010 CFR

2010-01-01

... fissile material package shall derive a number “N” based on all the following conditions being satisfied.... The value of the CSI may be zero provided that an unlimited number of packages are subcritical, such...) of this section. Any CSI greater than zero must be rounded up to the first decimal place. (c) For a...

PACKAGING CERTIFICATION PROGRAM METHODOLOGY FOR DETERMINING DOSE RATES FOR SMALL GRAM QUANTITIES IN SHIPPING PACKAGINGS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nathan, S.; Loftin, B.; Abramczyk, G.

The Small Gram Quantity (SGQ) concept is based on the understanding that small amounts of hazardous materials, in this case radioactive materials (RAM), are significantly less hazardous than large amounts of the same materials. This paper describes a methodology designed to estimate an SGQ for several neutron and gamma emitting isotopes that can be shipped in a package compliant with 10 CFR Part 71 external radiation level limits regulations. These regulations require packaging for the shipment of radioactive materials, under both normal and accident conditions, to perform the essential functions of material containment, subcriticality, and maintain external radiation levels withinmore » the specified limits. By placing the contents in a helium leak-tight containment vessel, and limiting the mass to ensure subcriticality, the first two essential functions are readily met. Some isotopes emit sufficiently strong photon radiation that small amounts of material can yield a large dose rate outside the package. Quantifying the dose rate for a proposed content is a challenging issue for the SGQ approach. It is essential to quantify external radiation levels from several common gamma and neutron sources that can be safely placed in a specific packaging, to ensure compliance with federal regulations. The Packaging Certification Program (PCP) Methodology for Determining Dose Rate for Small Gram Quantities in Shipping Packagings provides bounding shielding calculations that define mass limits compliant with 10 CFR 71.47 for a set of proposed SGQ isotopes. The approach is based on energy superposition with dose response calculated for a set of spectral groups for a baseline physical packaging configuration. The methodology includes using the MCNP radiation transport code to evaluate a family of neutron and photon spectral groups using the 9977 shipping package and its associated shielded containers as the base case. This results in a set of multipliers for 'dose per particle' for each spectral group. For a given isotope, the source spectrum is folded with the response for each group. The summed contribution from all isotopes determines the total dose from the RAM in the container.« less

Functions of Nano-Materials in Food Packaging

NASA Astrophysics Data System (ADS)

Yap, Ray Chin Chong; Kwablah, Amegadze Paul Seyram; He, Jiating; Li, Xu

Food packaging has been changing from bulky and rigid form in the past to different variation of lights and plastic packagings. Regardless of the changes, the packaging must be able to uphold its original function which is to serve as food containment as well as to protect the food from the external environment. Coupled with the increasing consumer’s awareness on food waste, higher standard of living, technological developments are underway to enhance the shelf-life of packed food as well as methods to provide indications of food packaging environment. There are many different indicators for food spoilage, but two commonly found gases in food packaging are oxygen and carbon dioxide. Oxygen is the main mechanism for food spoilage, while carbon dioxide is often used in modified-atmosphere-packaging. There are also different methods of gas scavenging and/or sensing techniques based on different concepts in the literature. In this review, the focus will be on nano-materials, namely titanium dioxide, silica, zeolites and metal organic frameworks. This review is structured in a manner to highlight how each material can be used in both gas scavenging and/or indicators applications. The last part of the review focuses on the approach and some key considerations when integrating nano-materials into the plastic film.

Hyperspectral imaging for differentiation of foreign materials from pinto beans

NASA Astrophysics Data System (ADS)

Mehrubeoglu, Mehrube; Zemlan, Michael; Henry, Sam

2015-09-01

Food safety and quality in packaged products are paramount in the food processing industry. To ensure that packaged products are free of foreign materials, such as debris and pests, unwanted materials mixed with the targeted products must be detected before packaging. A portable hyperspectral imaging system in the visible-to-NIR range has been used to acquire hyperspectral data cubes from pinto beans that have been mixed with foreign matter. Bands and band ratios have been identified as effective features to develop a classification scheme for detection of foreign materials in pinto beans. A support vector machine has been implemented with a quadratic kernel to separate pinto beans and background (Class 1) from all other materials (Class 2) in each scene. After creating a binary classification map for the scene, further analysis of these binary images allows separation of false positives from true positives for proper removal action during packaging.

Suture Products and Techniques: What to Use, Where, and Why.

PubMed

Regula, Christie G; Yag-Howard, Cyndi

2015-10-01

There are an increasing number of wound closure materials and suturing techniques described in the dermatologic and surgery literature. A dermatologic surgeon's familiarity with these materials and techniques is important to supplement his or her already established practices and improve surgical outcomes. To perform a thorough literature review of wound closure materials (sutures, tissue adhesives, surgical tape, and staples) and suturing techniques and to outline how and when to use them. A literature review was conducted using PubMed and other online search engines. Keywords searched included suture, tissue adhesive, tissue glue, surgical tape, staples, dermatologic suturing, and suturing techniques. Numerous articles outline the utility of various sutures, surgical adhesives, surgical tape, and staples in dermatologic surgery. In addition, there are various articles describing classic and novel suturing techniques along with their specific uses in cutaneous surgery. Numerous factors must be considered when choosing a wound closure material and suturing technique. These include wound tension, desire for wound edge eversion/inversion, desired hemostasis, repair type, patient's ability to care for the wound and return for suture removal, skin integrity, and wound location. Careful consideration of these factors and proper execution of suturing techniques can lead to excellent cosmetic results.

Materials in Manufacturing and Packaging Systems as Sources of Elemental Impurities in Packaged Drug Products: A Literature Review.

PubMed

Jenke, Dennis R; Stults, Cheryl L M; Paskiet, Diane M; Ball, Douglas J; Nagao, Lee M

Elemental impurities in drug products can arise from a number of different sources and via a number of different means, including the active pharmaceutical ingredient, excipients, the vehicle, and leaching of elemental entities that are present in the drug product's manufacturing or packaging systems. Thus, knowledge about the presence, level, and likelihood of leaching of elemental entities in manufacturing and packaging systems is relevant to understanding how these systems contribute to a drug product's total elemental impurity burden. To that end, a joint team from the Extractables and Leachables Safety Information Exchange (ELSIE) Consortium and the International Pharmaceutical Aerosol Consortium on Regulation and Science (IPAC-RS) has conducted a review of the available literature on elemental entities in pharmaceutically relevant polymers and the presence of these elemental entities in material extracts and/or drug products. This review article contains the information compiled from the available body of literature and considers two questions: (1) What elemental entities are present in the relevant polymers and materials and at what levels are they present? (2) To what extent are these elemental entities leached from these materials under conditions relevant to the manufacturing and storage/distribution of solution drug products? Conclusions drawn from the compiled data are as follows: (1) Elemental entities are present in the materials used to construct packaging and manufacturing systems as these materials either contain these elemental entities as additives or are exposed to elemental entities during their production. (2) Unless the elemental entities are parts of the materials themselves (for example, SiO 2 in glass) or intentionally added to the materials (for example, metal stearates in polymers), their incidental amounts in the materials are generally low. (3) When elemental entities are present in materials and systems, generally only a very small fraction of the total available amount of the entity can be leached under conditions that are relevant to packaged drug products. Thus, while sources of certain elemental impurities may be ubiquitous in the natural environment, they are not ubiquitous in materials used in pharmaceutical packaging and manufacturing systems and when they are present, they are not extensively leached under relevant conditions. The information summarized here can be utilized to aid the elemental impurity risk assessment process by providing the identities of commonly reported elements and data to support probability estimates of those becoming elemental impurities in the drug product. Furthermore, recommendations are made related to establishing elements of potential product impact for individual materials. Extraneous impurities in drug products provide no therapeutic benefit and thus should be known and controlled. Elemental impurities can arise from a number of sources and by a number of means, including the leaching of elemental entities from drug product packaging and manufacturing systems. To understand the extent to which materials used in packaging systems contain elemental entities and the extent to which those entities leach into drug products to become elemental impurities, the Extractables and Leachables Safety Information Exchange (ELSIE) and International Pharmaceutical Aerosol Consortium on Regulation and Science (IPAC-RS) Consortia have jointly performed a literature review on this subject. Using the compiled information, it was concluded that while packaging materials may contain elemental entities, unless those entities are intentional parts of the materials, the amounts of those elemental entities are generally low. Furthermore, generally only a very small fraction of the total available amount of the entity can be leached under conditions that are relevant to packaged drug products. Thus, risk assessment of sources of elemental impurities in drug products that may be related to materials used in pharmaceutical packaging and manufacturing systems can utilize the information and recommendations presented here. © PDA, Inc. 2015.

49 CFR 173.29 - Empty packagings.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Empty packagings. 173.29 Section 173.29... SHIPMENTS AND PACKAGINGS Preparation of Hazardous Materials for Transportation § 173.29 Empty packagings. (a) General. Except as otherwise provided in this section, an empty packaging containing only the residue of a...

Effectiveness of antimicrobial food packaging materials.

PubMed

Cooksey, K

2005-10-01

Antimicrobial additives have been used successfully for many years as direct food additives. The literature provides evidence that some of these additives may be effective as indirect food additives incorporated into food packaging materials. Antimicrobial food packaging is directed toward the reduction of surface contamination of processed, prepared foods such as sliced meats and Frankfurter sausages (hot dogs). The use of such packaging materials is not meant to be a substitute for good sanitation practices, but it should enhance the safety of food as an additional hurdle for the growth of pathogenic and/or spoilage microorganisms. Studies have focused on establishing methods for coating low-density polyethylene film or barrier films with methyl cellulose as a carrier for nisin. These films have significantly reduced the presence of Listeria monocytogenes in solutions and in vacuum packaged hot dogs. Other research has focused on the use of chitosan to inhibit L. monocytogenes and chlorine dioxide sachets for the reduction of Salmonella on modified atmosphere-packaged fresh chicken breasts. Overall, antimicrobial packaging shows promise as an effective method for the inhibition of certain bacteria in foods, but barriers to their commercial implementation continue to exist.

The LARSYS educational package: Instructor's notes. [instructional materials for training people to analyze remotely sensed data

NASA Technical Reports Server (NTRS)

Lindenlaub, J. C.; Davis, S. M.

1974-01-01

Materials are presented for assisting instructors in teaching the LARSYS Educational Package, which is a set of instructional materials to train people to analyze remotely sensed multispectral data. The seven units of the package are described. These units are: quantitative remote sensing, overview of the LARSYS software system, the 2780 remote terminal, demonstration of LARSYS on the 2780 remote terminal, exercises, guide to multispectral data analysis, and a case study using LARSYS for analysis of LANDSAT data.

Implementation of New Process Models for Tailored Polymer Composite Structures into Processing Software Packages

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nguyen, Ba Nghiep; Jin, Xiaoshi; Wang, Jin

2010-02-23

This report describes the work conducted under the Cooperative Research and Development Agreement (CRADA) (Nr. 260) between the Pacific Northwest National Laboratory (PNNL) and Autodesk, Inc. to develop and implement process models for injection-molded long-fiber thermoplastics (LFTs) in processing software packages. The structure of this report is organized as follows. After the Introduction Section (Section 1), Section 2 summarizes the current fiber orientation models developed for injection-molded short-fiber thermoplastics (SFTs). Section 3 provides an assessment of these models to determine their capabilities and limitations, and the developments needed for injection-molded LFTs. Section 4 then focuses on the development of amore » new fiber orientation model for LFTs. This model is termed the anisotropic rotary diffusion - reduced strain closure (ARD-RSC) model as it explores the concept of anisotropic rotary diffusion to capture the fiber-fiber interaction in long-fiber suspensions and uses the reduced strain closure method of Wang et al. to slow down the orientation kinetics in concentrated suspensions. In contrast to fiber orientation modeling, before this project, no standard model was developed to predict the fiber length distribution in molded fiber composites. Section 5 is therefore devoted to the development of a fiber length attrition model in the mold. Sections 6 and 7 address the implementations of the models in AMI, and the conclusions drawn from this work is presented in Section 8.« less

Observation of a periodic array of flux-closure quadrants in strained ferroelectric PbTiO 3 films

DOE PAGES

Tang, Y. L.; Zhu, Y. L; Ma, Xiuliang; ...

2015-05-01

Nanoscale ferroelectrics are expected to exhibit various exotic domain configurations, such as the full flux-closure pattern that is well known in ferromagnetic materials. Here we observe not only the atomic morphology of the flux-closure quadrant but also a periodic array of flux closures in ferroelectric PbTiO 3 films, mediated by tensile strain on a GdScO 3 substrate. Using aberration-corrected scanning transmission electron microscopy, we directly visualize an alternating array of clockwise and counterclockwise flux closures, whose periodicity depends on the PbTiO 3 film thickness. In the vicinity of the core, the strain is sufficient to rupture the lattice, with strainmore » gradients up to 10 9 per meter. We found engineering strain at the nanoscale may facilitate the development of nanoscale ferroelectric devices.« less

Effect of γ-irradiation on commercial polypropylene based mono and multi-layered retortable food packaging materials

NASA Astrophysics Data System (ADS)

George, Johnsy; Kumar, R.; Sajeevkumar, V. A.; Sabapathy, S. N.; Vaijapurkar, S. G.; Kumar, D.; Kchawahha, A.; Bawa, A. S.

2007-07-01

Irradiation processing of food in the prepackaged form may affect chemical and physical properties of the plastic packaging materials. The effect of γ-irradiation doses (2.5-10.0 kGy) on polypropylene (PP)-based retortable food packaging materials, were investigated using Fourier transform infrared (FTIR) spectroscopic analysis, which revealed the changes happening to these materials after irradiation. The mechanical properties decreased with irradiation while oxygen transmission rate (OTR) was not affected significantly. Colour measurement indicated that Nylon 6 containing multilayer films became yellowish after irradiation. Thermal characterization revealed the changes in percentage crystallinity.

Novel food packaging systems with natural antimicrobial agents.

PubMed

Irkin, Reyhan; Esmer, Ozlem Kizilirmak

2015-10-01

A new type of packaging that combines food packaging materials with antimicrobial substances to control microbial surface contamination of foods to enhance product microbial safety and to extend shelf-life is attracting interest in the packaging industry. Several antimicrobial compounds can be combined with different types of packaging materials. But in recent years, since consumer demand for natural food ingredients has increased because of safety and availability, these natural compounds are beginning to replace the chemical additives in foods and are perceived to be safer and claimed to alleviate safety concerns. Recent research studies are mainly focused on the application of natural antimicrobials in food packaging system. Biologically derived compounds like bacteriocins, phytochemicals, enzymes can be used in antimicrobial food packaging. The aim of this review is to give an overview of most important knowledge about application of natural antimicrobial packagings with model food systems and their antimicrobial effects on food products.

Single level microelectronic device package with an integral window

DOEpatents

Peterson, Kenneth A.; Watson, Robert D.

2003-12-09

A package with an integral window for housing a microelectronic device. The integral window is bonded directly to the package without having a separate layer of adhesive material disposed in-between the window and the package. The device can be a semiconductor chip, CCD chip, CMOS chip, VCSEL chip, laser diode, MEMS device, or IMEMS device. The package can be formed of a multilayered LTCC or HTCC cofired ceramic material, with the integral window being simultaneously joined to the package during cofiring. The microelectronic device can be flip-chip interconnected so that the light-sensitive side is optically accessible through the window. A glob-top encapsulant or protective cover can be used to protect the microelectronic device and electrical interconnections. The result is a compact, low profile package having an integral window that is hermetically sealed to the package prior to mounting and interconnecting the microelectronic device.

Computational modelling of a thermoforming process for thermoplastic starch

NASA Astrophysics Data System (ADS)

Szegda, D.; Song, J.; Warby, M. K.; Whiteman, J. R.

2007-05-01

Plastic packaging waste currently forms a significant part of municipal solid waste and as such is causing increasing environmental concerns. Such packaging is largely non-biodegradable and is particularly difficult to recycle or to reuse due to its complex composition. Apart from limited recycling of some easily identifiable packaging wastes, such as bottles, most packaging waste ends up in landfill sites. In recent years, in an attempt to address this problem in the case of plastic packaging, the development of packaging materials from renewable plant resources has received increasing attention and a wide range of bioplastic materials based on starch are now available. Environmentally these bioplastic materials also reduce reliance on oil resources and have the advantage that they are biodegradable and can be composted upon disposal to reduce the environmental impact. Many food packaging containers are produced by thermoforming processes in which thin sheets are inflated under pressure into moulds to produce the required thin wall structures. Hitherto these thin sheets have almost exclusively been made of oil-based polymers and it is for these that computational models of thermoforming processes have been developed. Recently, in the context of bioplastics, commercial thermoplastic starch sheet materials have been developed. The behaviour of such materials is influenced both by temperature and, because of the inherent hydrophilic characteristics of the materials, by moisture content. Both of these aspects affect the behaviour of bioplastic sheets during the thermoforming process. This paper describes experimental work and work on the computational modelling of thermoforming processes for thermoplastic starch sheets in an attempt to address the combined effects of temperature and moisture content. After a discussion of the background of packaging and biomaterials, a mathematical model for the deformation of a membrane into a mould is presented, together with its finite element discretisation. This model depends on material parameters of the thermoplastic and details of tests undertaken to determine these and the results produced are given. Finally the computational model is applied for a thin sheet of commercially available thermoplastic starch material which is thermoformed into a specific mould. Numerical results of thickness and shape for this problem are given.

Near optimal pentamodes as a tool for guiding stress while minimizing compliance in 3d-printed materials: A complete solution to the weak G-closure problem for 3d-printed materials

NASA Astrophysics Data System (ADS)

Milton, Graeme W.; Camar-Eddine, Mohamed

2018-05-01

For a composite containing one isotropic elastic material, with positive Lame moduli, and void, with the elastic material occupying a prescribed volume fraction f, and with the composite being subject to an average stress, σ0 , Gibiansky, Cherkaev, and Allaire provided a sharp lower bound Wf(σ0) on the minimum compliance energy σ0 :ɛ0 , in which ɛ0 is the average strain. Here we show these bounds also provide sharp bounds on the possible (σ0 ,ɛ0) -pairs that can coexist in such composites, and thus solve the weak G-closure problem for 3d-printed materials. The materials we use to achieve the extremal (σ0 ,ɛ0) -pairs are denoted as near optimal pentamodes. We also consider two-phase composites containing this isotropic elasticity material and a rigid phase with the elastic material occupying a prescribed volume fraction f, and with the composite being subject to an average strain, ɛ0. For such composites, Allaire and Kohn provided a sharp lower bound W˜f(ɛ0) on the minimum elastic energy σ0 :ɛ0 . We show that these bounds also provide sharp bounds on the possible (σ0 ,ɛ0) -pairs that can coexist in such composites of the elastic and rigid phases, and thus solve the weak G-closure problem in this case too. The materials we use to achieve these extremal (σ0 ,ɛ0) -pairs are denoted as near optimal unimodes.

Flexible, liquid core light guide with focusing and light shaping attachments

DOEpatents

Wojcik, R.F.; Majewski, S.; Zorn, C.J.; Kross, B.

1999-04-20

A liquid light guide system for ultraviolet light is disclosed that has a light shaping arrangement for the emitted light, a stable liquid core and sheath and reliable and effective end closures. The end closures include a metal crimping arrangement that utilizes two layers of deformable materials to prevent cracking of endplugs. 19 figs.

Effect of nano packaging on preservation quality of Nanjing 9108 rice variety at high temperature and humidity.

PubMed

Wang, Fan; Hu, Qiuhui; Mugambi Mariga, Alfred; Cao, Chongjiang; Yang, Wenjian

2018-01-15

A nano packaging material containing nano Ag, nano TiO 2 , nano attapulgite and SiO 2 was prepared, and its impact on quality of Nanjing 9108 rice at 37°C and 85% relative humidity was studied. Effects of the packaging on ambient gases and chromatic aberration of rice were determined. Moreover, oxidation level, molds growth and flavor of rice were also analyzed. Results showed that nano packaging material had antimicrobial effects and maintained low O 2 and high CO 2 content in the packages. The packages thereby inhibited the growth of molds and the production of fatty acids, restrained the increase of lipase activity, and reduced the oxidation of fats and proteins. As a result, the production of yellow and white-belly rice were inhibited. Furthermore, the color and flavor of rice were maintained. Therefore, the nano-packing material could be applied for preservation of rice to improve preservation quality. Copyright © 2017 Elsevier Ltd. All rights reserved.

49 CFR 173.162 - Gallium.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 2 2014-10-01 2014-10-01 false Gallium. 173.162 Section 173.162 Transportation... PACKAGINGS Non-bulk Packaging for Hazardous Materials Other Than Class 1 and Class 7 § 173.162 Gallium. (a) Except when packaged in cylinders or steel flasks, gallium must be packaged in packagings which meet the...

49 CFR 173.162 - Gallium.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 2 2012-10-01 2012-10-01 false Gallium. 173.162 Section 173.162 Transportation... PACKAGINGS Non-bulk Packaging for Hazardous Materials Other Than Class 1 and Class 7 § 173.162 Gallium. (a) Except when packaged in cylinders or steel flasks, gallium must be packaged in packagings which meet the...

49 CFR 173.162 - Gallium.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 2 2013-10-01 2013-10-01 false Gallium. 173.162 Section 173.162 Transportation... PACKAGINGS Non-bulk Packaging for Hazardous Materials Other Than Class 1 and Class 7 § 173.162 Gallium. (a) Except when packaged in cylinders or steel flasks, gallium must be packaged in packagings which meet the...

49 CFR 173.36 - Hazardous materials in Large Packagings.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Packagings (e.g., 51H) are only authorized for use with flexible inner packagings. (3) Friction. The nature and thickness of the outer packaging must be such that friction during transportation is not likely to... transportation in inner packagings appropriately resistant to an increase of internal pressure likely to develop...

49 CFR 173.415 - Authorized Type A packages.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 2 2011-10-01 2011-10-01 false Authorized Type A packages. 173.415 Section 173... REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Class 7 (Radioactive) Materials § 173.415 Authorized Type A packages. The following packages are authorized for shipment if they do not contain quantities exceeding A1 or...

49 CFR 173.415 - Authorized Type A packages.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 2 2013-10-01 2013-10-01 false Authorized Type A packages. 173.415 Section 173... REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Class 7 (Radioactive) Materials § 173.415 Authorized Type A packages. The following packages are authorized for shipment if they do not contain quantities exceeding A1 or...

49 CFR 173.415 - Authorized Type A packages.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Authorized Type A packages. 173.415 Section 173... REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Class 7 (Radioactive) Materials § 173.415 Authorized Type A packages. The following packages are authorized for shipment if they do not contain quantities exceeding A1 or...

49 CFR 173.415 - Authorized Type A packages.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 2 2012-10-01 2012-10-01 false Authorized Type A packages. 173.415 Section 173... REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Class 7 (Radioactive) Materials § 173.415 Authorized Type A packages. The following packages are authorized for shipment if they do not contain quantities exceeding A1 or...

49 CFR 173.206 - Packaging requirements for chlorosilanes.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Packaging requirements for chlorosilanes. 173.206...-GENERAL REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Non-bulk Packaging for Hazardous Materials Other Than Class 1 and Class 7 § 173.206 Packaging requirements for chlorosilanes. (a) When § 172.101 of this...

Testing of candidate waste-package backfill and canister materials for basalt

NASA Astrophysics Data System (ADS)

Wood, M. I.; Anderson, W. J.; Aden, G. D.

1982-09-01

The Basalt Waste Isolation Project (BWIP) is developing a multiple-barrier waste package to contain high-level nuclear waste as part of an overall system (e.g., waste package, repository sealing system, and host rock) designed to isolate the waste in a repository located in basalt beneath the Hanford Site, Richland, Washington. The three basic components of the waste package are the waste form, the canister, and the backfill. An extensive testing program is under way to determine the chemical, physical, and mechanical properties of potential canister and backfill materials. The data derived from this testing program will be used to recommend those materials that most adequately perform the functions assigned to the canister and backfill.

Physics of Failure Analysis of Xilinx Flip Chip CCGA Packages: Effects of Mission Environments on Properties of LP2 Underfill and ATI Lid Adhesive Materials

NASA Technical Reports Server (NTRS)

Suh, Jong-ook

2013-01-01

The Xilinx Virtex 4QV and 5QV (V4 and V5) are next-generation field-programmable gate arrays (FPGAs) for space applications. However, there have been concerns within the space community regarding the non-hermeticity of V4/V5 packages; polymeric materials such as the underfill and lid adhesive will be directly exposed to the space environment. In this study, reliability concerns associated with the non-hermeticity of V4/V5 packages were investigated by studying properties and behavior of the underfill and the lid adhesvie materials used in V4/V5 packages.

Nanotechnology: An Untapped Resource for Food Packaging.

PubMed

Sharma, Chetan; Dhiman, Romika; Rokana, Namita; Panwar, Harsh

2017-01-01

Food commodities are packaged and hygienically transported to protect and preserve them from any un-acceptable alteration in quality, before reaching the end-consumer. Food packaging continues to evolve along-with the innovations in material science and technology, as well as in light of consumer's demand. Presently, the modern consumers of competitive economies demands for food with natural quality, assured safety, minimal processing, extended shelf-life and ready-to-eat concept. Innovative packaging systems, not only ascertains transit preservation and effective distribution, but also facilitates communication at the consumer levels. The technological advances in the domain of food packaging in twenty-first century are mainly chaired by nanotechnology, the science of nano-materials. Nanotechnology manipulates and creates nanometer scale materials, of commercial and scientific relevance. Introduction of nanotechnology in food packaging sector has significantly addressed the food quality, safety and stability concerns. Besides, nanotechnology based packaging intimate's consumers about the real time quality of food product. Additionally, nanotechnology has been explored for controlled release of preservatives/antimicrobials, extending the product shelf life within the package. The promising reports for nanotechnology interventions in food packaging have established this as an independent priority research area. Nanoparticles based food packages offer improved barrier and mechanical properties, along with food preservation and have gained welcoming response from market and end users. In contrary, recent advances and up-liftment in this area have raised various ethical, environmental and safety concerns. Policies and regulation regarding nanoparticles incorporation in food packaging are being reviewed. This review presents the existing knowledge, recent advances, concerns and future applications of nanotechnology in food packaging sector.

Nanotechnology: An Untapped Resource for Food Packaging

PubMed Central

Sharma, Chetan; Dhiman, Romika; Rokana, Namita; Panwar, Harsh

2017-01-01

Food commodities are packaged and hygienically transported to protect and preserve them from any un-acceptable alteration in quality, before reaching the end-consumer. Food packaging continues to evolve along-with the innovations in material science and technology, as well as in light of consumer's demand. Presently, the modern consumers of competitive economies demands for food with natural quality, assured safety, minimal processing, extended shelf-life and ready-to-eat concept. Innovative packaging systems, not only ascertains transit preservation and effective distribution, but also facilitates communication at the consumer levels. The technological advances in the domain of food packaging in twenty-first century are mainly chaired by nanotechnology, the science of nano-materials. Nanotechnology manipulates and creates nanometer scale materials, of commercial and scientific relevance. Introduction of nanotechnology in food packaging sector has significantly addressed the food quality, safety and stability concerns. Besides, nanotechnology based packaging intimate's consumers about the real time quality of food product. Additionally, nanotechnology has been explored for controlled release of preservatives/antimicrobials, extending the product shelf life within the package. The promising reports for nanotechnology interventions in food packaging have established this as an independent priority research area. Nanoparticles based food packages offer improved barrier and mechanical properties, along with food preservation and have gained welcoming response from market and end users. In contrary, recent advances and up-liftment in this area have raised various ethical, environmental and safety concerns. Policies and regulation regarding nanoparticles incorporation in food packaging are being reviewed. This review presents the existing knowledge, recent advances, concerns and future applications of nanotechnology in food packaging sector. PMID:28955314

49 CFR 175.630 - Special requirements for Division 6.1 (poisonous) material and Division 6.2 (infectious...

Code of Federal Regulations, 2014 CFR

2014-10-01

... (infectious substances) materials. (a) A package required to bear a POISON, POISON INHALATION HAZARD, or... person may operate an aircraft that has been used to transport any package required to bear a POISON or POISON INHALATION HAZARD label unless, upon removal of such package, the area in the aircraft in which it...

49 CFR 175.630 - Special requirements for Division 6.1 (poisonous) material and Division 6.2 (infectious...

Code of Federal Regulations, 2011 CFR

2011-10-01

... (infectious substances) materials. (a) A package required to bear a POISON, POISON INHALATION HAZARD, or... person may operate an aircraft that has been used to transport any package required to bear a POISON or POISON INHALATION HAZARD label unless, upon removal of such package, the area in the aircraft in which it...

49 CFR 175.630 - Special requirements for Division 6.1 (poisonous) material and Division 6.2 (infectious...

Code of Federal Regulations, 2012 CFR

2012-10-01

... (infectious substances) materials. (a) A package required to bear a POISON, POISON INHALATION HAZARD, or... person may operate an aircraft that has been used to transport any package required to bear a POISON or POISON INHALATION HAZARD label unless, upon removal of such package, the area in the aircraft in which it...