8. BRIDGEWORK PLANKING FROM EAST SIDE WITH TWIN FALLS MAIN ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. BRIDGEWORK PLANKING FROM EAST SIDE WITH TWIN FALLS MAIN CANAL HEADWORKS IN DISTANCE; LOOKING WEST. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

14. VIEW WEST, DETAIL OF MITTER SILL, SHOWING MISSING PLANKS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. VIEW WEST, DETAIL OF MITTER SILL, SHOWING MISSING PLANKS - Bald Eagle Cross-Cut Canal Lock, North of Water Street along West Branch of Susquehanna River South bank, 500 feet East of Jay Street Bridge, Lock Haven, Clinton County, PA

15. SAME ROOMVIEW SOUTH TOWARDS THREE BOATS UNDER CONSTRUCTION. FLATBOTTOM ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. SAME ROOM-VIEW SOUTH TOWARDS THREE BOATS UNDER CONSTRUCTION. FLAT-BOTTOM SECTION IN FOREGROUND ON SAW HORSES (NOTE FRAME PATTERNS ON BOTTOM PLANKS), BACKGROUND BOATS BEING FRAMED AND PLANKED. - Lowell's Boat Shop, 459 Main Street, Amesbury, Essex County, MA

On Correlated Failures in Survivable Storage Systems

DTIC Science & Technology

2002-05-01

Littlewood, D.R. Miller, “Conceptual modeling of coincident failures in multiversion software”, IEEE Transactions on Software Engineering, Volume: 15 Issue...Recovery in Multiversion Software”. IEEE Transaction on Software Engineering, Vol. 16 No.3, March 1990 [Plank1997] J. Plank “A tutorial on Reed-Solomon

16. LOG AND PLANK BRIDGE ON ACCESS ROAD NEAR BRIDGE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

16. LOG AND PLANK BRIDGE ON ACCESS ROAD NEAR BRIDGE SITE; SAME STRUCTURE AS SHOWN IN PHOTO #12. ZION NP NEGATIVE NO. 967 ZIO. - Zion-Mount Carmel Highway, Virgin River Bridge, Spanning North Fork of Virgin River on Zion-Mount Carmel Highway, Springdale, Washington County, UT

26. Historic American Buildings Survey L. C. Durette, Photographer MORTISE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

26. Historic American Buildings Survey L. C. Durette, Photographer MORTISE HOLES IN GIRT OVER WINDOW, EAST ELEVATION, SHOWING PLAIN SOFFIT ABOVE ORIGINAL WINDOW. SMALL MORTISE FOR PLANK + WINDOW JAMB (MISSING), LARGER MORTISE FOR BRACE, ORIGINAL PLANK AT RIGHT OF WINDOW - Doe Garrison, Lamprey River & Great Bay, Newmarket, Rockingham County, NH

Precipitation projections under GCMs perspective and Turkish Water Foundation (TWF) statistical downscaling model procedures

NASA Astrophysics Data System (ADS)

Dabanlı, İsmail; Şen, Zekai

2018-04-01

The statistical climate downscaling model by the Turkish Water Foundation (TWF) is further developed and applied to a set of monthly precipitation records. The model is structured by two phases as spatial (regional) and temporal downscaling of global circulation model (GCM) scenarios. The TWF model takes into consideration the regional dependence function (RDF) for spatial structure and Markov whitening process (MWP) for temporal characteristics of the records to set projections. The impact of climate change on monthly precipitations is studied by downscaling Intergovernmental Panel on Climate Change-Special Report on Emission Scenarios (IPCC-SRES) A2 and B2 emission scenarios from Max Plank Institute (EH40PYC) and Hadley Center (HadCM3). The main purposes are to explain the TWF statistical climate downscaling model procedures and to expose the validation tests, which are rewarded in same specifications as "very good" for all stations except one (Suhut) station in the Akarcay basin that is in the west central part of Turkey. Eventhough, the validation score is just a bit lower at the Suhut station, the results are "satisfactory." It is, therefore, possible to say that the TWF model has reasonably acceptable skill for highly accurate estimation regarding standard deviation ratio (SDR), Nash-Sutcliffe efficiency (NSE), and percent bias (PBIAS) criteria. Based on the validated model, precipitation predictions are generated from 2011 to 2100 by using 30-year reference observation period (1981-2010). Precipitation arithmetic average and standard deviation have less than 5% error for EH40PYC and HadCM3 SRES (A2 and B2) scenarios.

Max Planck Institute for Human Development and Education: Annual Report 1990.

ERIC Educational Resources Information Center

Max-Planck-Institut fuer Bildungsforschung, Berlin (West Germany).

The Max Planck Institute for Human Development and Education in Germany consists of four research centers dealing with the following topics: sociology and the study of the life course; development and socialization; psychology and human development; and school systems and instruction. This English-language annual report of the Planck Institute,…

Blocks, Bricks, and Planks: Relationships between Affordance and Visuo-Spatial Constructive Play Objects

ERIC Educational Resources Information Center

Ness, Daniel; Farenga, Stephen J.

2016-01-01

The authors consider the strengths and weaknesses of three different visuo-spatial constructive play object (VCPO) types--blocks, bricks, and planks--and their impact on the development of creativity in spatial thinking and higher learning during free play. Each VCPO has its own set of attributes, they note, leading to different purposes,…

Analysis of rolling fracture of the conticasted and tandem rolled blanks of low alloyed aluminum

NASA Astrophysics Data System (ADS)

Li, Yong; Zeng, Lingping; Jiao Xie, Xian

2018-01-01

Optical microscopy, electron microscopy and energy spectrum were used to test the morphology of grains, as-cast microstructure and secondary phases in confiscated and tandem rolled planks of 8011 low alloying aluminum alloy. It can be concluded that the existence of inhomogeneous secondary FeSiAl phases lead to the fracture of planks during rolling.

75 FR 14623 - Notice of Availability of the Draft Imperial Sand Dunes Recreation Area Management Plan and Draft...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-26

... Concern (ACEC), Plank Road and East Mesa. The preferred alternative would continue the 298-acre Plank Road... preferred alternative would reduce the East Mesa ACEC from 6,454 acres to 5,799 acres, which overlaps the Planning Area. The East Mesa ACEC would continue to protect biological resources and other resource values...

Multilocus sequence identification of Penicillium species in cork bark during plank preparation for the manufacture of stoppers.

PubMed

Serra, Rita; Peterson, Stephen; Venâncio, Armando

2008-04-01

Despite several studies reporting Penicillium as one of the most frequent fungal genera in cork planks, the isolates were rarely identified to species level. We conducted a detailed study to identify Penicillium species from the field to the factory environment prior to and after boiling the cork planks. A total of 84 samples were analyzed. Of the 486 Penicillium isolates phenotypically identified, 32 representative or unusual strains were selected for identification by multilocus DNA sequence type. Cork proved to be a rich source of Penicillium biodiversity. A total of 30 taxa were recognized from cork including rarely seen species and 6 phylogenetically unique groups. Spores of some species lodged deep in cork can survive the boiling process. P. glabrum, P. glandicola and P. toxicarium, species with high CFU numbers in the field, are still frequently present in cork after boiling. Other species are killed by the boiling treatment and replaced by Penicillium species originating from the factory environment. Species known to contribute to cork taint were isolated at all stages. Good manufacturing practices are necessary at all stages in the preparation of cork planks to minimize the load of Penicillium species that produce cork taint.

Human responses to augmented virtual scaffolding models.

PubMed

Hsiao, Hongwei; Simeonov, Peter; Dotson, Brian; Ammons, Douglas; Kau, Tsui-Ying; Chiou, Sharon

2005-08-15

This study investigated the effect of adding real planks, in virtual scaffolding models of elevation, on human performance in a surround-screen virtual reality (SSVR) system. Twenty-four construction workers and 24 inexperienced controls performed walking tasks on real and virtual planks at three virtual heights (0, 6 m, 12 m) and two scaffolding-platform-width conditions (30, 60 cm). Gait patterns, walking instability measurements and cardiovascular reactivity were assessed. The results showed differences in human responses to real vs. virtual planks in walking patterns, instability score and heart-rate inter-beat intervals; it appeared that adding real planks in the SSVR virtual scaffolding model enhanced the quality of SSVR as a human - environment interface research tool. In addition, there were significant differences in performance between construction workers and the control group. The inexperienced participants were more unstable as compared to construction workers. Both groups increased their stride length with repetitions of the task, indicating a possibly confidence- or habit-related learning effect. The practical implications of this study are in the adoption of augmented virtual models of elevated construction environments for injury prevention research, and the development of programme for balance-control training to reduce the risk of falls at elevation before workers enter a construction job.

4. DETAIL: Crib supporting bay, east of west (or upper) ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. DETAIL: Crib supporting bay, east of west (or upper) gate, looking south from inside lock. Tenon of crib timber is quite visible since the inner wall 2' planking has been burned off. Spikes holding remaining planks are discernable. - Wabash & Erie Canal, Lock No. 2, 8 miles east of Fort Wayne, adjacent to U.S. Route 24, New Haven, Allen County, IN

[A failed experiment - Carl Friedrich von Weizsäcker, Jürgen Habermas and the Max-Planck Society].

PubMed

Leendertz, Ariane

2014-01-01

From 1970 to 1980 Carl Friedrich von Weizsäcker headed the Max-Planck-lnstitut zur Erforschung der Lebensbedingungen der wissenschaftlich-technischen Welt (MPI for the study of the living conditions of the world of science and technology) in Starnberg, jointly with Jürgen Habermas since 1971. From the start, the Max Planck Society regarded the new institute as an experiment that might perhaps be aborted a few years later. This is exactly what happened. With the retirement of Weizsäcker, his section was closed and the whole institute was renamed. In 1981. Habermas resigned, and then the institute was closed. This paper focusses on some of the problem constellations within the institute that partly explain its development and eventual closure: its birth out of the idea of scientific policy advice, the debates within the Max Planck Society and the complex relationship between Weizsäcker and Jürgen Habermas.

8. SEDIMENTATION CHAMBER, VIEW UPSTREAM (PLANK COVER REMOVED FOR CLARITY). ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. SEDIMENTATION CHAMBER, VIEW UPSTREAM (PLANK COVER REMOVED FOR CLARITY). BOX FLUME DROPS SLIGHTLY INTO CHAMBER ON LEFT SIDE. CHAMBER IS A SERIES OF BAFFLES DESIGNED TO SLOW THE FLOW OF WATER. FLOW IS REDUCED TO ALLOW PARTICULATES TO SETTLE TO THE BOTTOM. TWO SCREENS (NOT SHOWN) FILTER LARGER DEBRIS. - Kalaupapa Water Supply System, Waikolu Valley to Kalaupapa Settlement, Island of Molokai, Kalaupapa, Kalawao County, HI

Stages in Educational Reform; The Max Planck Institute Has Produced a Report on Education.

ERIC Educational Resources Information Center

Pfeffer, Gottfried

1981-01-01

Outlines the Max Planck Institute's exhaustive report on West German educational trends since World War II. An analysis of the effects of changing social values and demographic factors on educational policy, school organization, enrollment trends, curriculum design, and teaching methods is included. (AM)

["A decision meaning a new foundation...": from the Kaiser Wilhelm Institute for Anthropology, Human Genetics and Eugenics to the Max Planck Institute for Molecular Genetics].

PubMed

Sachse, Carola

2011-01-01

The Max Planck Institute for Molecular Genetics (MPIMG) in Berlin-Dahlem dates its establishment to 1964. Its homepage makes no mention of its predecessor institutes, the Kaiser Wilhelm Institute for Anthropology, Human Genetics and Eugenics (KWIA) and the subsequent MPI for Comparative Genetics and Hereditary Pathology (MPIVEE). This article traces the two critical phases of transition regarding the constellations of academic staff, institutional and epistemic ruptures and continuities specific to the era. Only one of the five department heads from the final war years, Hans Nachtsheim, remained a researcher within the Max Planck Society (MPG); he nevertheless continued to advocate the pre-war and wartime eugenic agenda in the life sciences and social policy. The generational change of 1959/60 became a massive struggle within the institute, in which microbial genetics (with Fritz Kaudewitz) was pitted against human genetics (with Friedrich Vogel) and managed to establish itself after a fresh change in personnel in 1964/65. For the Dahlem institute, this involved a far-reaching reorientation of its research, but for the genetically oriented life sciences in the Max Planck Society as a whole it only meant that molecular biology, which was already being pursued in the West German institutes, gained an additional facility. With this realignment of research traditions, the Society was able to draw a line under the Nazi past without having to address it head-on.

Modelling climate change effects on Atlantic salmon: Implications for mitigation in regulated rivers.

PubMed

Sundt-Hansen, L E; Hedger, R D; Ugedal, O; Diserud, O H; Finstad, A G; Sauterleute, J F; Tøfte, L; Alfredsen, K; Forseth, T

2018-08-01

Climate change is expected to alter future temperature and discharge regimes of rivers. These regimes have a strong influence on the life history of most aquatic river species, and are key variables controlling the growth and survival of Atlantic salmon. This study explores how the future abundance of Atlantic salmon may be influenced by climate-induced changes in water temperature and discharge in a regulated river, and investigates how negative impacts in the future can be mitigated by applying different regulated discharge regimes during critical periods for salmon survival. A spatially explicit individual-based model was used to predict juvenile Atlantic salmon population abundance in a regulated river under a range of future water temperature and discharge scenarios (derived from climate data predicted by the Hadley Centre's Global Climate Model (GCM) HadAm3H and the Max Plank Institute's GCM ECHAM4), which were then compared with populations predicted under control scenarios representing past conditions. Parr abundance decreased in all future scenarios compared to the control scenarios due to reduced wetted areas (with the effect depending on climate scenario, GCM, and GCM spatial domain). To examine the potential for mitigation of climate change-induced reductions in wetted area, simulations were run with specific minimum discharge regimes. An increase in abundance of both parr and smolt occurred with an increase in the limit of minimum permitted discharge for three of the four GCM/GCM spatial domains examined. This study shows that, in regulated rivers with upstream storage capacity, negative effects of climate change on Atlantic salmon populations can potentially be mitigated by release of water from reservoirs during critical periods for juvenile salmon. Copyright © 2018. Published by Elsevier B.V.

Proteins as Supramolecular Building Blocks for Responsive Materials and Nanodevices

DTIC Science & Technology

2015-12-20

Wojciechowski, Han Yue Zheng, James E. A. Webb, Céline Valéry, Pall Thordarson , Natalie O. V. Plank, Juliet A. Gerrard, Justin M. Hodgkiss. Functional...materials: Eakins GL, Pandey R, Wojciechowski JP, Zheng  HY, Webb  JEA, Valéry C,  Thordarson  P, Plank NOV, Gerrard  JA, Hodgkiss  JM. 2015:  Functional

On the quantization of wave fields⋆

NASA Astrophysics Data System (ADS)

Rosenfeld, L.

2017-04-01

Originally published in German "Zur Quantelung der Wellenfelder" in Annalen der Physik 397, 113 (1930). Submitted for publication on March 18, 1930Translated by Donald Salisbury, Max-Planck-Institut für Wissenschaftsgeschichte, Berlin and Austin College, Sherman, TX, USA and Kurt Sundermeyer, Max-Planck-Institut für Wissenschaftsgeschichte, Berlin. DSalisbury@austincollege.edu

[Effect of Core Muscle Strengthening Exercises (Including Plank and Side Plank) on Injury Rate in Male Adult Soccer Players: A Systematic Review].

PubMed

Blasimann, Angela; Eberle, Simon; Scuderi, Manuel Markus

2018-03-01

 Soccer is seen as highly intensive sport with an increased injury rate. Male adults are the players with the highest injury incidence. Accordingly, the importance of core muscle strengthening to prevent injury has increased in the past few years. Up to date, core muscle strengthening plays an important role in different prevention programs, such as the "FIFA 11 +". The aim of this systematic review was to investigate the effect of core muscle strengthening on injury rate in male adult soccer players, including at least the known and easy exercises "plank" and "side plank", on injury rate in male adult soccer players.  The databases PubMed, PEDro, Cochrane Library, SPORTDiscus and Cinahl were searched systematically. Included studies had to comprise exercises for core muscles as an intervention (as a part of a prevention program) for adult male soccer players. The control group had to continue their usual exercise routine. The exercises "plank" and "side plank" were mandatory elements of the training program. The number of injuries and/or the injury rate (per 1000 hours) were defined as outcomes. The quality of the included studies was assessed with the PEDro scale and the Risk of Bias tool.  Seven studies with 2491 participants in total could be included. Two studies found a significant decrease in the injury rate in the intervention group (p < 0.05, p < 0.001 respectively). In two studies, no significance level was reported, but the training showed preventive effects in the intervention group. In the other three studies, no significant changes in the injury rate were found (p > 0.05).  The seven included studies differed greatly with respect to the applied methods, the chosen interventions and the obtained results. Furthermore, core muscles were never trained separately but were always part of a program containing other preventive elements. Therefore, it was difficult to compare the studies. However, prevention programs including strengthening exercises for core muscles tend to positively affect the injury rate. Based on the literature found, the research question cannot definitively be answered. In the future, further studies are needed which investigate the effect of isolated core muscle training on the injury rate of soccer players. © Georg Thieme Verlag KG Stuttgart · New York.

Influence of Body Position on Shoulder and Trunk Muscle Activation During Resisted Isometric Shoulder External Rotation.

PubMed

Krause, David A; Dueffert, Lucas G; Postma, Jaclyn L; Vogler, Eric T; Walsh, Amy J; Hollman, John H

External rotation (ER) strengthening of the shoulder is an integral component of rehabilitative and preventative programs for overhead athletes. A variety of shoulder ER strengthening exercises are reported, including those intended to integrate the core musculature. The purpose of this study was to examine ER torque and electromyographic (EMG) activation of shoulder and trunk muscles while performing resisted isometric shoulder ER in 3 positions (standing, side lying, and side plank). Significantly greater force and shoulder muscle activation would be generated while side lying given the inherent stability of the position, and greater trunk muscle activation would be generated in the less stable plank position. Quasi-experimental repeated-measures study. Level 5. A convenience sample of 25 healthy overhead recreational athletes (9 men, 16 women) participated in this study. EMG electrodes were placed on the infraspinatus, posterior deltoid, middle trapezius, multifidi, internal obliques, and external obliques. EMG signals were normalized to a maximal isometric contraction. Participants performed resisted isometric ER in standing, side-lying, and side plank positions. Results were analyzed using a repeated-measures analysis of variance with post hoc Bonferroni corrections (α = 0.05). There was no significant difference in ER torque between positions (α = 0.05). A significant difference in EMG activity of shoulder and trunk musculature between positions was found in 7 of the 8 muscles monitored. Significantly greater EMG activity in the infraspinatus, middle trapezius, and the nondominant external and internal obliques was found in the side plank position as compared with standing and side lying. While there was no difference in ER torque between the 3 exercise positions, EMG activity of the shoulder and trunk muscles was dependent on body position. If a clinician is seeking to integrate trunk muscle activation while performing shoulder ER strengthening, the side plank position is preferred as compared with standing or side lying.

The historical development of modern virus research in Germany, especially in the Kaiser-Wilhelm-/Max-Planck-Society, 1936--1954.

PubMed

Butenandt, A

1977-01-01

This is lecture on the historical development of modern virus research in Germany to introduce a symposium dedicated to Prof. Werner Schäfer, Tübingen, on the occasion of his 65th birthday. The author was set the task of relating from his memories the beginning of modern virus research in Germany. This research has, since 1936, essentially taken place in the Kaiser-Wilhelm/Max-Planck-Society and in 1954 led to the founding of the Max-Planck-Institute for Virus Research in Tübingen, an institute which to the present day owes its scientific reputation in considerable part to the activity of Werner Schäfer. Since the author personally experienced and participated in the Institute's development from 1936-1954, his remarks are predominantly influenced by personal recollections, which have been sharpended by a renewed study of old records in the 'Library and Archive of the History of the Max-Planck-Gesellschaft', Berlin-Dahlem.

Short Gamma-ray Bursts: Observations and Physics

NASA Astrophysics Data System (ADS)

Janka, H.-Thomas

2007-04-01

The aim of the workshop, which will be held at the scenic Ringberg castle, is supposed to bring together astrophysicists, physicists, and astronomers from different fields in order to discuss recent observational and theoretical discoveries and developments on short gamma-ray bursts. In particular, we plan to address the following topics: * recent short GRB observations * environments and host galaxies of short GRBs * is there a 3rd class of GRBs? * modeling GRB engines and jet outflows * rate and redshift predictions for short GRBs * the fireball model and short GRBs * gravitational-wave signals from short GRBs * neutrino signals from short GRBs * microphysics needed for modeling short GRBs and their engines Scientific and Local organizing committee members: H.-Thomas Janka (Max Planck Institute for Astrophysics, Garching), Miguel Aloy (University of Valencia), Jochen Greiner (Max Planck Institute for Extraterrestrial Physics), Sandra Savaglio (Max Planck Institute for Extraterrestrial Physics), Shri Kulkarni (California Institute of Technology, Pasadena)

Noncommutative effects in entropic gravity

NASA Astrophysics Data System (ADS)

Gregory, C. M.; Pinzul, A.

2013-09-01

We analyze the question of possible quantum corrections in the entropic scenario of emergent gravity. Using a fuzzy sphere as a natural quasiclassical approximation for the spherical holographic screen, we analyze whether it is possible to observe such corrections to Newton’s law in principle. The main outcome of our analysis is that without the complete knowledge of the quantum dynamics of the microscopic degrees of freedom, any Plank-scale correction cannot be trusted. Some perturbative corrections might produce reliable predictions well below the Plank scale.

PREFACE: International Conference on Topics in Astroparticle and Underground Physics (TAUP 2011)

NASA Astrophysics Data System (ADS)

Oberauer, Lothar; Raffelt, Georg; Wagner, Robert

2012-07-01

The 12th edition of the International Conference on Topics in Astroparticle and Underground Physics (TAUP 2011) was held 5-9 September 2011 in Munich (and for the first time in Germany). It was organized by the Max Planck Institute for Physics (MPP), the Technical University Munich (TUM) and the Cluster of Excellence 'Origin and Structure of the Universe'. The conference was held in the 'Künstlerhaus', a traditional downtown location for artistic festivities. The meeting attracted 317 participants (61 of which were women) from 29 countries, see figure below. The topics covered by the meeting were Cosmology and particle physics, Dark matter and its detection, Neutrino physics and astrophysics, Gravitational waves and High-energy astrophysics and cosmic rays, and the various interfaces between these areas. The scientific sessions consisted of five mornings of plenary talks, four afternoons of parallel sessions, and an evening poster session. The co-founder of the conference series, Alessandro Bottino, has decided to retire from the position of chairman of the TAUP Steering Committee after the completion of TAUP 2011. On behalf of all followers of this series, we thank him for having started these inspiring events and his many years of dedicated service. We thank all speakers, conveners and participants as well as the members of the organizing, steering and international advisory committee for making this a successful and memorable meeting. Lothar Oberauer, Georg Raffelt, Robert Wagner Proceedings editors Figure Committees International Advisory Committee G AntonUniversity of Erlangen E AprileColumbia University M Baldo-CeolinUniversity of Padova R BattistonUniversity of Perugia & INFN L BergströmUniversity Stockholm R BernabeiUniversity of Rome 'Tor Vergata' A BettiniLSC Canfranc P BinetruyAPC Paris J BlümerKarlsruhe Institute of Technology B CabreraStanford University A CaldwellMax Planck Institute for Physics M ChenQueens University E CocciaUniversity of Rome 'Tor Vergata' K DanzmannMax Planck Institute for Gravitational Physics S DodelsonFermilab G DomogatskyINR Moscow E FioriniUniversità di Milano Bicocca & INFN K FreeseUniversity of Michigan M FukugitaICRR Tokyo T GaisserUniversity of Delaware G GerbierCEA Saclay F HalzenUniversity of Wisconsin W HaxtonLNBL & UC Berkeley J HoughGlasgow University E KomatsuUniversity of Texas E KatsavounidisMassachusetts Institute of Technology M LindnerMax Planck Institute for Nuclear Physics K LeskoLBNL & UC Berkeley A McDonaldQueens University & SNO Laboratory H MurayamaIPMU Tokyo & UC Berkeley A OlintoUniversity of Chicago L ResvanisUniversity of Athens A RubbiaETH Zurich S SarkarUniversity of Oxford A SmirnovICTP Trieste N SmithSNO Laboratory C SpieringDESY Zeuthen N SpoonerUniversity of Sheffield Y SuzukiICRR Tokyo M TeshimaMax Planck Institute for Physics J W F ValleIFIC & University of Valencia L VotanoLNGS E WaxmanWeizmann Institute J WilkersonUniversity of North Carolina TAUP Steering Committee F T AvignoneUniversity of South Carolina B C BarishCaltech E BellottiUniversity of Milan Bicoccia & INFN J BernabeuUniversity of Valencia A BottinoUniversity of Turin & INFN (chair) N FornengoUniversity of Turin & INFN T KajitaICRR Tokyo C W KimJohns Hopkins University & KIAS V MatveevINR Moscow G RaffeltMax Planck Institute for Physics D SinclairUniversity of Carleton M SpiroCEA Saclay Parallel Session Conveners Dark Matter - Candidates and Searches J-C LanfranchiTechnische Universität München T Marrodán UndagoitiaUniversity of Zurich T BringmannUniversität Hamburg Cosmology J WellerLudwig-Maximilians-Universität München S HannestadUniversity of Aarhus Double Beta Decay, Neutrino Mass M HirschIFIC/CSIC - University of Valencia A GiulianiCNRS Orsay Neutrino Oscillations T LachenmaierUniversität Tübingen F SuekaneTohoku University Low-Energy Neutrinos (Geo, Solar, Supernova) A DigheTIFR Mumbai M ChenQueen's University M WurmUniversität Hamburg Gravitational Waves E CocciaUniversity of Rome Tor Vergata and INFN S MarkaColumbia University Astrophysical Messengers (Neutrinos, Gamma-Rays, Cosmic Rays) R M WagnerMax-Planck-Institut für Physik M KachelriessUniversity of Trondheim M KowalskiUniversity of Bonn Organizing Committee N FornengoTorino University and INFN B MajorovitsMax-Planck-Institut für Physik L OberauerTechnische Universität M ü nchen (co-chair) G RaffeltMax-Planck-Institut für Physik (co-chair) S RodríguezMax-Planck-Institut für Physik (conference secretary) S SchönertTechnische Universität München D SinclairSNO Laboratory & Carleton University R M WagnerMax-Planck-Institut für Physik (scientific secretary) B WankerlExcellence Cluster 'Origin and Structure of the Universe' M WurmTechnische Universität München S ZollingerMax-Planck-Institut für Physik Conference photograph

[Following the American example? American models for hospital medicine and research: the case of the Kerckhoff Institute in Bad Nauheim].

PubMed

Timmermann, Carsten

2010-01-01

This essay examines how and why American models were applied in the reorganization of West German hospitals and medical research centers in the post-war period. After discussing why American clinical medical centers turned into model institutions over the last century or so, a case study is discussed in some detail: the Kerckhoff Institute for cardiovascular research in Bad Nauheim, since 1951 an institute within the Max Planck Society with its own research clinic (which was unusual for Max Planck Institutes). The history of this institution illustrates which local and specific considerations drove historical actors to embrace American models. German academic and administrative realities, however, imposed tight constraints on the implementation of US institutional models.

Max Weber's Critique of the Bureaucratisation of Education

ERIC Educational Resources Information Center

Madan, Amman

2014-01-01

In this commentary, the author discusses the critique by Max Weber and his views on bureaucratisation of education. The modern school, said Max Weber (1864-1920) over a hundred years ago, has as its educational ideal the bureaucrat and no longer the cultivated elite of older times. The shift to modernity and to its characteristic institution, the…

[Anatomical Vitamin C-Research during National Socialism and the Post-war Period: Max Clara's Human Experiments at the Munich Anatomical Institute].

PubMed

Schûtz, Mathias; Schochow, Maximilian; Waschke, Jens; Marckmann, Georg; Steger, Florian

2014-01-01

In autumn of 1942, Max Clara (1899-1966) became chairman of the anatomical institute Munich. There, he intensified his research concerning the proof of vitamin C with the bodies of executed prisoners which were delivered by the Munich-Stadelheim prison. This research on human organs was pursued by applying ascorbic acid (Cebion) to prisoners before their execution. The paper investigates this intensified and radicalized anatomical research through human experiments, which Max Clara conducted in Munich and published from Istanbul during the postwar years, as well as its scientific references from the Nazi period.

German science. Max Planck charts new path.

PubMed

Koenig, R

2000-06-09

Germany's premier basic research organization, the Max Planck Society, released a long-awaited blueprint for change during its annual meeting this week, recommending that the society's nearly 3000 scientists embrace more interdisciplinary and international projects in a range of new research priorities. The report, called Max Planck 2000-Plus, is the product of an 18-month-long internal review. Its recommendations were formulated by some two dozen Max Planck researchers and administrators, who sought input from every institute.

27. DETAIL: West gate sill, looking northwest toward the south ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

27. DETAIL: West gate sill, looking northwest toward the south facing wall. The chamber wall planks and spikes can be clearly seen. Possible remnants of a gate lie in the bay west of the gate. A portion of the chamber wall's 2' plank sheathing has sprung away from the wall and a small corner can be seen in the right foreground, next to the protective plastic cover. - Wabash & Erie Canal, Lock No. 2, 8 miles east of Fort Wayne, adjacent to U.S. Route 24, New Haven, Allen County, IN

Variation of arsenic concentration on surfaces of in-service CCA-treated wood planks in a park and its influencing field factors.

PubMed

Tang, Ya; Gao, Wei; Wang, Xiuli; Ding, Shiming; An, Taicheng; Xiao, Weiyang; Wong, Ming H; Zhang, Chaosheng

2015-01-01

Wood preservatives can protect wood from dry rot, fungi, mould and insect damage, and chromated copper arsenate (CCA) has been used as an inorganic preservative for many years. However, wood treated with CCA has been restricted from residential uses in the EU from June 30, 2004, due to its potential toxicity. Such a regulation is not in place in China yet, and CCA-treated wood is widely used in public parks. A portable XRF analyser was used to investigate arsenic (As) concentration on surfaces of in-service CCA-treated wood planks in a popular park as well as the influencing field factors of age in-service, immersion and human footfall. With a total of 1207 readings, the observed As concentrations varied from below the detection limit (<10 mg/kg) to 15,746 mg/kg with a median of 1160 mg/kg. Strong variation of As concentrations were observed in different wood planks of the same age, on the surface of the same piece of wood, inside the same piece of wood, and different surfaces of walkway planks, hand rails and poles in the field. The oldest planks exhibited high As concentrations, which was related to its original treatment with high retention of CCA preservative. The effect of immersion in the field for about 4 months was insignificant for As concentration on the surfaces. However, a significant reduction of As was observed for immersion combined with human footfall (wiping by shoes). Human traffic in general caused slightly reduced and more evenly distributed As concentrations on the wood surfaces. The strong variation, slow aging and relatively weak immersion effects found in this study demonstrate that the in-service CCA-treated wood poses potential health risks to the park users, due to easy dermal contact especially when the wood is wet after rainfall. It is suggested that further comprehensive investigations and risk assessments of CCA-treated wood in residential areas in China are needed, and precautionary measures should be considered to reduce the potential risks to residents and visitors, especially children.

Orthotropic creep in polyethylene glycol impregnated archaeological oak from the Vasa ship - Results of creep experiments in a museum-like climate

NASA Astrophysics Data System (ADS)

Vorobyev, Alexey; van Dijk, Nico P.; Kristofer Gamstedt, E.

2018-02-01

Creep in archaeological oak samples and planks from the Vasa ship impregnated with polyethylene glycol (PEG) has been studied in museum-like climate. Creep studies of duration up to three years have been performed in nearly constant relative humidity and temperature of the controlled museum climate. Cubic samples were subjected to compressive creep tests in all orthotropic directions. Additionally, the creep behaviour of planks with and without PEG and of recent oak was tested in four-point bending. The experimental results have been summarised and also compared with reference results from recent oak wood. The effect of variable ambient conditions on creep and mass changes is discussed. The experimental results of creep in the longitudinal direction showed deformations even for the low stresses. There is relatively much more scatter in creep behaviour, and not all samples showed linear viscoelastic response. The creep in radial and tangential directions of the cubes and the plank samples showed a strong dependency on the ambient conditions. Some samples showed expansion for decreasing moisture content, possibly caused by the thermal expansion of the PEG component. For the planks, increasing creep deformation was observed induced by changing ambient conditions. Such behaviour may be related to e.g. oscillations in ambient conditions and presence of PEG in the wood cell wall and cell lumen. The behaviour of PEG archaeological wood depends on the level of deterioration that occurred over centuries. However, although the findings presented here apply to this specific case, they provide a unique view on such wood.

Device for absorbing mechanical shock

DOEpatents

Newlon, Charles E.

1980-01-01

This invention is a comparatively inexpensive but efficient shock-absorbing device having special application to the protection of shipping and storage cylinders. In a typical application, two of the devices are strapped to a cylinder to serve as saddle-type supports for the cylinder during storage and to protect the cylinder in the event it is dropped during lifting or lowering operations. In its preferred form, the invention includes a hardwood plank whose grain runs in the longitudinal direction. The basal portion of the plank is of solid cross-section, whereas the upper face of the plank is cut away to form a concave surface fittable against the sidewall of a storage cylinder. The concave surface is divided into a series of segments by transversely extending, throughgoing relief slots. A layer of elastomeric material is positioned on the concave face, the elastomer being extrudable into slots when pressed against the segments by a preselected pressure characteristic of a high-energy impact. The compressive, tensile, and shear properties of the hardwood and the elastomer are utilized in combination to provide a surprisingly high energy-absorption capability.

Device for absorbing mechanical shock

DOEpatents

Newlon, C.E.

1979-08-29

This invention is a comparatively inexpensive but efficient shock-absorbing device having special application to the protection of shipping and storage cylinders. In a typical application, two of the devices are strapped to a cylinder to serve as saddle-type supports for the cylinder during storage and to protect the cylinder in the event it is dropped during lifting or lowering operations. In its preferred form, the invention includes a hardwood plank whose grain runs in the longitudinal direction. The basal portion of the plank is of solid cross-section, whereas the upper face of the plank is cut away to form a concave surface fittable against the sidewall of a storage cylinder. The concave surface is divided into a series of segments by transversely extending, throughgoing relief slots. A layer of elastomeric material is positioned on the concave face, the elastomer being extrudable into slots when pressed against the segments by a preselected pressure characteristic of a high-energy impact. The compressive, tensile, and shear properties of the hardwood and the elastomer are utilized in combination to provide a surprisingly high energy-absorption capability.

7. View north at back (canal side) of culvert inlet, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. View north at back (canal side) of culvert inlet, with canal bank completely removed. Background to foreground: back of inlet headwall with tops of high inlet barrels exposed; vertical transition wall between high inlet barrels and low, interior, inlet barrels; tops of low interior barrels; vertical heartening planks and low cutoff wall at site of former canal edge of canal bank; dewatered canal bed and plank sheathing on top of culvert barrels beneath canal bed. - Delaware & Raritan Canal, Ten Mile Run Culvert, 1.5 miles South of Blackwells Road, East Millstone, Somerset County, NJ

International Symposium on New Trends in Photoelectrochemistry Held in Altavilla Milicia (Pa), Italy on 22-26 September 1991. Extended Abstracts

DTIC Science & Technology

1991-09-01

Exchange Between Semiconductors and Molecules (Redox Ions)" F. Willig, Fritz - Haber Institut der Max-Planck Gesellschaft, Berlin GERMANY 8.00 p.m.: Dinner...Lecture "Photoelectrochemical Catalysis by Small Semiconducting Particles" H. Gerischer, Fritz - Haber Institut der Max-Planck- Gesellschaft, Berlin, GERMANY...examples of photoelectrochemical etching procedures with elemental, II-VI and III-V compound semiconducting electrodes will be discussed. 25 FRITZ - HABER

The problem of 2,4,6-trichloroanisole in cork planks studied by attenuated total reflection infrared spectroscopy: proof of concept.

PubMed

Garcia, Ana R; Lopes, Luís F; Brito de Barros, Ricardo; Ilharco, Laura M

2015-01-14

Attenuated total reflection infrared spectroscopy (ATR-IR) proved to be a promising detection technique for 2,4,6-trichloroanisole (TCA), which confers organoleptic defects to bottled alcoholic beverages, allowing the proposal of a criterion for cork plank acceptance when meant for stopper production. By analysis of a significant number of samples, it was proved that the presence of TCA, even in very low concentrations, imparts subtle changes to the cork spectra, namely, the growth of two new bands at ∼1417 (νC═C of TCA ring) and 1314 cm–1 (a shifted νCC of TCA) and an increase in the relative intensities of the bands at ∼1039 cm–1 (δCO of polysaccharides) and ∼813 cm–1 (τCH of suberin), the latter by overlapping with intense bands of TCA. These relative intensities were evaluated in comparison to a fingerprint of suberin (νasC–O–C), at 1161 cm–1. On the basis of those spectral variables, a multivariate statistics linear analysis (LDA) was performed to obtain a discriminant function that allows classifying the samples according to whether they contain or not TCA. The methodology proposed consists of a demanding acceptance criterion for cork planks destined for stopper production (with the guarantee of nonexistence of TCA) that results from combining the quantitative results with the absence of the two TCA correlated bands. ATR infrared spectroscopy is a nondestructive and easy to apply technique, both on cork planks and on stoppers, and has proven more restrictive than other techniques used in the cork industry that analyze the cleaning solutions. At the level of proof of concept, the method here proposed is appealing for high-value stopper applications.

Methodology for cork plank characterization (Quercus suber L.) by near-infrared spectroscopy and image analysis

NASA Astrophysics Data System (ADS)

Prades, Cristina; García-Olmo, Juan; Romero-Prieto, Tomás; García de Ceca, José L.; López-Luque, Rafael

2010-06-01

The procedures used today to characterize cork plank for the manufacture of cork bottle stoppers continue to be based on a traditional, manual method that is highly subjective. Furthermore, there is no specific legislation regarding cork classification. The objective of this viability study is to assess the potential of near-infrared spectroscopy (NIRS) technology for characterizing cork plank according to the following variables: aspect or visual quality, porosity, moisture and geographical origin. In order to calculate the porosity coefficient, an image analysis program was specifically developed in Visual Basic language for a desktop scanner. A set comprising 170 samples from two geographical areas of Andalusia (Spain) was classified into eight quality classes by visual inspection. Spectra were obtained in the transverse and tangential sections of the cork planks using an NIRSystems 6500 SY II reflectance spectrophotometer. The quantitative calibrations showed cross-validation coefficients of determination of 0.47 for visual quality, 0.69 for porosity and 0.66 for moisture. The results obtained using NIRS technology are promising considering the heterogeneity and variability of a natural product such as cork in spite of the fact that the standard error of cross validation (SECV) in the quantitative analysis is greater than the standard error of laboratory (SEL) for the three variables. The qualitative analysis regarding geographical origin achieved very satisfactory results. Applying these methods in industry will permit quality control procedures to be automated, as well as establishing correlations between the different classification systems currently used in the sector. These methods can be implemented in the cork chain of custody certification and will also provide a certainly more objective tool for assessing the economic value of the product.

[Critical mass, explosive participation at the Max-Planck Institute about research of the living conditions of the scientific-technical world in Starnberg].

PubMed

Sonntag, Philipp

2014-01-01

Reviewers of the Max-Planck-Institut zur Erforschung der Lebensbedingungen der wissenschaftlich-technischen Welt (MPIL) did focus upon an abundance of vague reports of evaluative commissions, of benchmarking, of scientific modes. Thus it remained rather neglected, what staff actually had researched. An example: Progression and end of project AKR (Work-Consumption-Assessment) does display all kinds of related emotions at MPIL, and the sensitive guidance by Carl Friedrich von Weizsäcker.

The ionized gas at the centre of IC 10: a possible localized chemical pollution by Wolf-Rayet stars

NASA Astrophysics Data System (ADS)

López-Sánchez, Á. R.; Mesa-Delgado, A.; López-Martín, L.; Esteban, C.

2011-03-01

We present results from integral field spectroscopy with the Potsdam Multi-Aperture Spectrograph at the 3.5-m telescope at Calar Alto Observatory of the intense star-forming region [HL90] 111 at the centre of the starburst galaxy IC 10. We have obtained maps with a spatial sampling of 1 × 1 arcsec2= 3.9× 3.9 pc2 of different emission lines and analysed the extinction, physical conditions, nature of the ionization and chemical abundances of the ionized gas, as well determined locally the age of the most recent star formation event. By defining several apertures, we study the main integrated properties of some regions within [HL90] 111. Two contiguous spaxels show an unambiguous detection of the broad He IIλ4686 emission line, this feature seems to be produced by a single late-type WN star. We also report a probable N and He enrichment in the precise spaxels where the Wolf-Rayet (WR) features are detected. The enrichment pattern is roughly consistent with that expected for the pollution of the ejecta of a single or a very small number of WR stars. Furthermore, this chemical pollution is very localized (˜2 arcsec ˜7.8 pc) and it should be difficult to detect in star-forming galaxies beyond the Local Volume. We also discuss the use of the most common empirical calibrations to estimate the oxygen abundances of the ionized gas in nearby galaxies from 2D spectroscopic data. The ionization degree of the gas plays an important role when applying these empirical methods, as they tend to give lower oxygen abundances with increasing ionization degree. Based on observations collected at the Centro Astrónomico Hispano Alemán (CAHA) at Calar Alto, operated jointly by the Max-Plank Institut für Astronomie and the Instituto de Astrofísica de Andalucía (CSIC).Visiting Astronomer at the Instituto de Astrofísica de Canarias.

A Case for Air Force Reorganization

DTIC Science & Technology

2013-04-01

overstaffing problem exists, sev- eral theories lend insight into why and how this overgrowth occurs. Noted German sociologist Max Weber discusses...USAF Almanac, 1980,” May 1980; “2010 USAF Almanac”; and “Air Force Strength from FY 1948–2012.” 9. Max Weber , On Charisma and Institution Building...MA: Belknap Press of Harvard University Press, 1957), 67. 22. Max Weber , The Theory of Social and Economic Organization, trans. A. M. Henderson and

The International Max Planck Research Schools for Molecular Biology and Neurosciences in Gttingen (Germany) as Examples for Joint Doctoral Training by a German University and Its Non-University Partners

ERIC Educational Resources Information Center

Burkhardt, Steffen; Neher, Erwin

2008-01-01

New concepts of higher education have recently been implemented through the MSc/PhD programmes in Molecular Biology and Neurosciences in the International Max Planck Research Schools, due to close cooperation between the University of Gttingen, three Max Planck Institutes and the German Primate Centre. The novel measures include a three stage…

MAX-DOAS observations and their application to the validation of satellite and model data in Wuxi, China

NASA Astrophysics Data System (ADS)

Wang, Y.; Wagner, T.; Xie, P.; Theys, N.; De Smedt, I.; Koukouli, M.; Stavrakou, T.; Beirle, S.; Li, A.

2015-12-01

Thomas Wagner1, Pinhua Xie2, Nicolas Theys3, Isabelle De Smedt3, MariLiza Koukouli4, Trissevgeni Stavrakou3, Steffen Beirle1, Ang Li2,1) Satellite group, Max Planck institute for Chemistry, Mainz, Germany2) Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Hefei, China 3) BIRA-IASB, Brussels, Belgium 4) Laboratory of Atmospheric Physics, Aristotle University of Thessaloniki, Greece From 2011 to 2014 a MAX-DOAS instrument developed by the Anhui Institute of Optics and Fine Mechanics institute is operated in Wuxi, China, which is locatd about 100 km west of Shanghai. We determine the tropospheric vertical column densities (VCDs), near surface concentrations and vertical profiles of aerosols, NO2, SO2, HCHO from the MAX-DOAS observations using the optimal estimation profile retrieval algorithm (refered to as "PriAM"). We verified the results by comparing them with results from independent techniques, such as sun photometer (AERONET), a visibility meter and a long-path DOAS instrument. We acquire the cloud and aerosol conditions using a cloud classification scheme based on the MAX-DOAS observations (Wang et al., AMTD, 2015). Based on the obtained results, we characterize the effect of the clouds on the trace gas and aerosol profiles retrieved from MAX-DOAS. Then we characterize the diurnal, annual and weekly variations of the trace gases and aerosols and validate the tropospheric trace gas VCDs derived from the Ozone Monitoring instrument (OMI) on the Aura satellite platform as well as the model results from the IMAGES, CHIMERE and Lotos-Euros models and analyse the agreement depending on the cloud and aerosol conditions. Besides the direct comparison with the satellite data, we also use the trace gas and aerosol profiles derived from MAX-DOAS to recalculate the air mass factor (AMF) for the satellite observations and to evaluate the corresponding improvement of the satellite VCDs. In some periods with strong aerosol pollution, we evaluate the effect of the aerosols on the satellite cloud retrievals and the corresponding errors of the tropospheric AMF of the trace gases. Here should be noted that aerosol effects on the AMF is not yet considered in the published satellite products, which can cause appreciable errors of the tropospheric VCD of satellite products around polluted regions.

Straight talk with... Martin Stratmann.

PubMed

Stratmann, Martin

2014-07-01

The 83 institutes and research facilities of the Max Planck Society, established in 1948, include some of the world's leading scholars in the life sciences, including 17 Noble Prize winners, and publish 15,000 research papers annually. For the past 18 years, biologists have stood at the helm of the prestigious German organization. But last month, an electrochemist and materials scientist, Martin Stratmann, began a six-year term as president of the Munich-based society.Stratmann, who is 60, served as the director of the Max Planck Institute for Iron Research in Düsseldorf since 2000, where he helped develop self-healing coatings that can protect steels and other metals from rust. Stratmann spoke with David Levine about his vision for the Max Planck Society and about what the change of guard will mean for biomedical research. The conversation has been edited for clarity.

Kurt Schaffner: from organic photochemistry to photobiology.

PubMed

Gärtner, Wolfgang

2012-06-01

Kurt Schaffner turned 80 this year. This perspective highlights his contributions to the research on the plant photoreceptor phytochrome, as many of the findings on structure and function of this molecule are tightly linked to the Max-Planck-Institute for Radiation Chemistry, where he was effective as Max-Planck director for more than twenty years.

Nontransformed, GM-CSF-dependent macrophage lines are a unique model to study tissue macrophage functions.

PubMed

Fejer, György; Wegner, Mareike Dorothee; Györy, Ildiko; Cohen, Idan; Engelhard, Peggy; Voronov, Elena; Manke, Thomas; Ruzsics, Zsolt; Dölken, Lars; Prazeres da Costa, Olivia; Branzk, Nora; Huber, Michael; Prasse, Antje; Schneider, Robert; Apte, Ron N; Galanos, Chris; Freudenberg, Marina A

2013-06-11

Macrophages are diverse cell types in the first line of antimicrobial defense. Only a limited number of primary mouse models exist to study their function. Bone marrow-derived, macrophage-CSF-induced cells with a limited life span are the most common source. We report here a simple method yielding self-renewing, nontransformed, GM-CSF/signal transducer and activator of transcription 5-dependent macrophages (Max Planck Institute cells) from mouse fetal liver, which reflect the innate immune characteristics of alveolar macrophages. Max Planck Institute cells are exquisitely sensitive to selected microbial agents, including bacterial LPS, lipopeptide, Mycobacterium tuberculosis, cord factor, and adenovirus and mount highly proinflammatory but no anti-inflammatory IL-10 responses. They show a unique pattern of innate responses not yet observed in other mononuclear phagocytes. This includes differential LPS sensing and an unprecedented regulation of IL-1α production upon LPS exposure, which likely plays a key role in lung inflammation in vivo. In conclusion, Max Planck Institute cells offer an useful tool to study macrophage biology and for biomedical science.

List of Participants

NASA Astrophysics Data System (ADS)

2007-11-01

Mohab Abou ZeidVrije Universiteit, Brussel Joke AdamKatholieke Universiteit Leuven Nikolas AkerblomMax-Planck-Institut für Physik, München Luis Fernando Alday Utrecht University Stelios Alexandris University of Patras Antonio Amariti Università di Milano-Bicocca Nicola Ambrosetti Université de Neuchâtel Pascal Anastasopoulos Università di Roma Tor Vergata Laura Andrianopoli Enrico Fermi Center Carlo Angelantonj Università di Torino Lilia Anguelova Queen Mary, University of London Daniel AreanUniversidade de Santiago de Compostela Gleb ArutyunovUtrecht University Spyros Avramis NTU Athens—University of Patras Ioannis Bakas University of Patras Subrata Bal Dublin Institute for Advanced Studies Igor Bandos Valencia University Jessica Barrett University of Iceland Marco Baumgartl Eidgenössische Technische Hochschule, Zürich Jacopo Bechi Università di Firenze James Bedford Queen Mary, University of London Jorge Bellorin Universidad Autonoma de Madrid Francesco Benini SISSA, Trieste Eric Bergshoeff Centre for Theoretical Physics, University of Groningen Gaetano BertoldiUniversity of Wales, Swansea Adel Bilal Laboratoire de Physique Théorique, École Normale Superieure, Paris Matthias Blau Université de Neuchâtel Johannes BroedelUniversität Hannover Felix Brümmer Universität Heidelberg Julio Cesar Bueno de Andrade São Paulo State University—UNESP Cliff Burgess McMaster University Agostino Butti Laboratoire de Physique Théorique, École Normale Superieure, Paris Marco Caldarelli Universitat de Barcelona Pablo G Camara Centre de Physique Théorique, École Polytechnique, Palaiseau Joan Camps Universitat de Barcelona Felipe Canoura FernandezUniversidade de Santiago de Compostela Luigi Cappiello Università di Napoli Federico II Luca Carlevaro École Polytechnique, Palaiseau Roberto Casero Centre de Physique Théorique, École Polytechnique, Palaiseau Claudio Caviezel Max-Planck-Institut für Physik, München Alessio Celi Universitat de Barcelona Anna Ceresole Istituto Nazionale di Fisica Nucleare and Università di Torino Kang Sin Choi University of Bonn Michele Cirafici University of Patras Andres Collinucci Katholieke Universiteit Leuven Aldo Cotrone Universitat de Barcelona Ben Craps Vrije Universiteit, Brussel Stefano Cremonesi SISSA, Trieste Gianguido Dall'Agata Padova University Sanjit Das Indian Institute of Technology, Kharagpur Forcella Davide SISSA, Trieste Jose A de Azcarraga Valencia University and Instituto de Fìsica Corpuscular (CSIC-UVEG), Valencia Sophie de BuylInstitut des Hautes Études Scientifiques, Bures-sur-Yvette Jean-Pierre Derendinger Université de Neuchâtel Stephane Detournay Università Degli Studi di Milano Paolo Di Vecchia NORDITA, København Oscar Dias Universitat de Barcelona Vladimir Dobrev Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, Sofia Joel Ekstrand Department of Theoretical Physics, Uppsala University Federico Elmetti Università di Milano I Diaconu Eugen University of Craiova Oleg Evnin Vrije Universiteit, Brussel Bo Feng Imperial College, London Livia Ferro Università di Torino Pau Figueras Universitat de Barcelona Raphael Flauger University of Texas at Austin Valentina Forini Università di Perugia Angelos Fotopoulos Università di Torino Denis Frank Université de Neuchâtel Lisa Freyhult Albert-Einstein-Institut, Golm Carlos Fuertes Instituto de Física Teórica, Madrid Matthias Gaberdiel Eidgenössische Technische Hochschule, Zürich Maria Pilar Garcia del Moral Università di Torino Daniel Gerber Instituto de Física Teórica, Madrid Valentina Giangreco Marotta Puletti Uppsala University Joaquim Gomis Universitat de Barcelona Gianluca Grignani Università di Perugia Luca Griguolo Università di Parma Umut Gursoy École Polytechnique, Palaiseau and École Normale Supérieure, Paris Michael Haack Ludwig-Maximilians-Universität, München Troels Harmark Niels Bohr Institute, København Alexander Haupt Imperial College, London Michal Heller Jagiellonian University, Krakow Samuli Hemming University of Iceland Yasuaki Hikida DESY, Hamburg Christian Hillmann Max-Planck-Institut für Gravitationsphysik, Potsdam Stephan Hoehne Max-Planck-Institut für Physik, München Gabriele Honecker CERN, Geneva Carlos Hoyos University of Wales, Swansea Mechthild Huebscher Consejo Superior de Investigaciones Cientificas, Madrid Matthias Ihl University of Texas at Austin Emiliano Imeroni University of Wales, Swansea Nikos Irges University of Crete Negru Iulian University of Craiova Matthias Kaminski Ludwig-Maximilians-Universität, München Stefanos Katmadas Universiteit Utrecht Shoichi Kawamoto Oxford University Christoph Keller Eidgenössische Technische Hochschule, Zürich Arjan Keurentjes Vrije Universiteit, Brussel Sadi Khodaee Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan, Iran Michael Kiermaier Massachusetts Institute of Technology, Cambridge, MA Elias Kiritsis Centre de Physique Théorique, École Polytechnique, Palaiseau and University of Crete Ingo KirschEidgenössische Technische Hochschule, Zürich Johanna Knapp CERN, Geneva Paul Koerber Max-Planck-Institut für Physik, München Simon Koers Max-Planck-Institut für Physik, München Anatoly Konechny Heriot-Watt University, Edinburgh Peter Koroteev Institute for Theoretical and Experimental Physics (ITEP), Moscow Daniel KreflLudwig-Maximilians-Universität and Max-Planck-Institut für Physik, München Chethan KrishnanUniversité Libre de Bruxelles Stanislav Kuperstein Université Libre de Bruxelles Alberto Lerda Università del Piemonte Orientale, Alessandria Roman Linares Universidad Autonoma Metropolitana, Iztapalapa, México Maria A Lledo Universidad de Valencia Dieter Luest Ludwig-Maximilians-Universität and Max-Planck-Institut für Physik, München Joseph Lykken Fermi National Accelerator Laboratory (Fermilab), Batavia, IL Carlo Maccaferri Vrije Universiteit, Brussel Oscar Macia Universidad de Valencia Tristan Maillard Centre de Physique Théorique, École Polytechnique, Palaiseau Diego Mansi Università Degli Studi di Milano Matteo Marescotti Università del Piemonte Orientale, Alessandria Alberto Mariotti Università di Milano-Bicocca Raffaele Marotta Istituto Nazionale di Fisica Nucleare, Napoli Alessio Marrani Istituto Nazionale di Fisica Nucleare and LNF, Firenze Luca Martucci Instituto de Física Teórica, Madrid and Katholieke Universiteit Leuven David Mateos University of California, Santa Barbara Andrea Mauri Università di Milano Liuba Mazzanti Università di Milano-Bicocca Patrick Meessen Instituto de Física Teórica, Universidad Autónoma de Madrid Lotta Mether Helsinki Institute of Physics Rene Meyer Max-Planck-Institut für Physik, München Giuseppe Milanesi SISSA, Trieste Cesar Miquel-Espanya Universitat de Valencia and Instituto de Física Corpuscular, Valencia Alexander Monin Institute for Theoretical and Experimental Physics (ITEP), Moscow and Moscow State University (MSU) Samuel Monnier Université de Genève Sergio Montero Instituto de Física Teórica, Madrid Nicola Mori Università di Firenze Alexander Marcel Morisse University of California, Santa Cruz Sebastian Moster Max-Planck-Institut für Physik, München Adele Nasti Queen Mary, University of London Vasilis Niarchos École Polytechnique, Palaiseau Emil Nissimov Institute for Nuclear Research and Nuclear Energy, Sofia Francesco Nitti École Polytechnique, Palaiseau Eoin O'Colgain Imperial College, London Niels Obers Niels Bohr Institute, København Rodrigo Olea Università Degli Studi di Milano Marta Orselli Niels Bohr Institute, København Enrico PajerLudwig-Maximilians-Universität, München Eran PaltiOxford University Georgios PapathanasiouBrown University, Providence, RI Angel ParedesCentre de Physique Théorique, École Polytechnique, Palaiseau Jeong-Hyuck ParkMax-Planck-Institut für Physik, München Sara PasquettiUniversità di Parma Silvia PenatiUniversità di Milano-Bicocca Igor PesandoUniversità di Torino Marios PetropoulosÉcole Polytechnique, Palaiseau Roberto PettorinoUniversità di Napoli Federico II Franco PezzellaIstituto Nazionale di Fisica Nucleare, Napoli Moises Picon PonceIstituto Nazionale di Fisica Nucleare, Padova Marco PirroneUniversità di Milano-Bicocca Erik PlauschinnMax-Planck-Institut für Physik, München Andre PloeghCentre for Theoretical Physics, University of Groningen Giuseppe PolicastroLaboratoire de Physique Théorique, École Normale Superieure, Paris Josep PonsUniversitat de Barcelona S Prem KumarUniversity of Wales, Swansea Nikolaos PrezasCERN, Geneva Carlo Alberto RattiUniversità di Milano-Bicocca Riccardo RicciImperial College, London Alejandro RiveroEscuela Universitaria Politécnica de Teruel, Universidad de Zaragoza Irene RodriguezInstituto de Física Teórica, Madrid Maria Jose RodriguezUniversitat de Barcelona Diederik RoestUniversitat de Barcelona Alberto RomagnoniLaboratoire de Physique Théorique d'Orsay, Paris Christian RomelsbergerDublin Institute for Advanced Studies Jan RosseelKatholieke Universiteit Leuven Sebastiano RossiEidgenössische Technische Hochschule, Zürich Felix RustMax-Planck-Institut für Physik, München Cheol RyouPohang University of Science and Technology (POSTECH) Christian SaemannDublin Institute for Advanced Studies Houman Safaai SISSA, Trieste Alberto SantambrogioIstituto Nazionale di Fisica Nucleare, Sezione di Milano Frank SaueressigUniversiteit Utrecht Ricardo SchiappaCERN, Geneva Cornelius Schmidt-ColinetEidgenössische Technische Hochschule, Zürich Maximilian Schmidt-SommerfeldMax-Planck-Institut für Physik, München Waldemar SchulginMax-Planck-Institut für Physik, München Claudio ScruccaUniversité de Neuchâtel Nathan SeibergInstitute of Advanced Studies, Princeton, NJ Domenico SeminaraUniversità di Firenze Alexander SevrinVrije Universiteit, Brussel Konstadinos SfetsosUniversity of Patras Kostas SiamposUniversity of Patras Christoph SiegUniversità Degli Studi di Milano Vaula Silvia Instituto de Física Teórica, Madrid Aaron Sim Imperial College, London Woojoo Sim Pohang University of Science and Technology (POSTECH) Sergey Slizovskiy Department of Theoretical Physics, Uppsala University Paul Smyth Katholieke Universiteit Leuven Corneliu Sochichiu Laboratori Nazionali di Frascati Dmitri Sorokin Istituto Nazionale di Fisica Nucleare, Padova Kellogg Stelle Imperial College, London Piotr Surowka Jagiellonian University, Krakow Yasutoshi Takayama Niels Bohr Institute, København Laura Tamassia Katholieke Universiteit Leuven Radu Tatar University of Liverpool Larus Thorlacius University of Iceland Paavo Tiitola Helsinki Institute of Physics Diego Trancanelli Stony Brook University, NY Michele TraplettiInstitut für Theoretische Physik, Universität Heidelberg Mario Trigiante Politecnico di Torino Angel Uranga CERN, Geneva and Instituto de Física Teórica, Madrid Roberto Valandro SISSA, Trieste Dieter Van den Bleeken Katholieke Universiteit Leuven Antoine Van Proeyen Katholieke Universiteit Leuven Thomas Van Riet Centre for Theoretical Physics, University of Groningen Pierre Vanhove Service de Physique Théorique, Saclay Oscar Varela Universidad de Valencia Alessandro Vichi Scuola Normale Superiore di Pisa Massimiliano VinconQueen Mary, University of London John Ward Queen Mary, University of London and CERN, Geneva Brian Wecht Massachusetts Institute of Technology, Cambridge, MA Marlene Weiss Eidgenössische Technische Hochschule, Zürich and CERN, Geneva Sebastian Weiss Université de Neuchâtel Alexander Wijns Vrije Universiteit, Brussel Przemek Witaszczyk Jagiellonian University, Krakow Timm Wrase University of Texas at Austin Jun-Bao Wu SISSA, Trieste Amos Yarom Ludwig-Maximilians-Universität, München Marco Zagermann Max-Planck-Institut für Physik, München Daniela Zanon Dipartimento di Fisica, Università di Milano Andrea Zanzi University of Bonn Andrey Zayakin Moscow State University (MSU) and Institute for Theoretical and Experimental Physics (ITEP), Moscow Konstantinos Zoubos Queen Mary, University of London

Does Anxiety Cause Freezing of Gait in Parkinson's Disease?

PubMed Central

Ehgoetz Martens, Kaylena A.; Ellard, Colin G.; Almeida, Quincy J.

2014-01-01

Individuals with Parkinson's disease (PD) commonly experience freezing of gait under time constraints, in narrow spaces, and in the dark. One commonality between these different situations is that they may all provoke anxiety, yet anxiety has never been directly examined as a cause of FOG. In this study, virtual reality was used to induce anxiety and evaluate whether it directly causes FOG. Fourteen patients with PD and freezing of gait (Freezers) and 17 PD without freezing of gait (Non-Freezers) were instructed to walk in two virtual environments: (i) across a plank that was located on the ground (LOW), (ii) across a plank above a deep pit (HIGH). Multiple synchronized motion capture cameras updated participants' movement through the virtual environment in real-time, while their gait was recorded. Anxiety levels were evaluated after each trial using self-assessment manikins. Freezers performed the experiment on two separate occasions (in their ON and OFF state). Freezers reported higher levels of anxiety compared to Non-Freezers (p<0.001) and all patients reported greater levels of anxiety when walking across the HIGH plank compared to the LOW (p<0.001). Freezers experienced significantly more freezing of gait episodes (p = 0.013) and spent a significantly greater percentage of each trial frozen (p = 0.005) when crossing the HIGH plank. This finding was even more pronounced when comparing Freezers in their OFF state. Freezers also had greater step length variability in the HIGH compared to the LOW condition, while the step length variability in Non-Freezers did not change. In conclusion, this was the first study to directly compare freezing of gait in anxious and non-anxious situations. These results present strong evidence that anxiety is an important mechanism underlying freezing of gait and supports the notion that the limbic system may have a profound contribution to freezing in PD. PMID:25250691

Does anxiety cause freezing of gait in Parkinson's disease?

PubMed

Ehgoetz Martens, Kaylena A; Ellard, Colin G; Almeida, Quincy J

2014-01-01

Individuals with Parkinson's disease (PD) commonly experience freezing of gait under time constraints, in narrow spaces, and in the dark. One commonality between these different situations is that they may all provoke anxiety, yet anxiety has never been directly examined as a cause of FOG. In this study, virtual reality was used to induce anxiety and evaluate whether it directly causes FOG. Fourteen patients with PD and freezing of gait (Freezers) and 17 PD without freezing of gait (Non-Freezers) were instructed to walk in two virtual environments: (i) across a plank that was located on the ground (LOW), (ii) across a plank above a deep pit (HIGH). Multiple synchronized motion capture cameras updated participants' movement through the virtual environment in real-time, while their gait was recorded. Anxiety levels were evaluated after each trial using self-assessment manikins. Freezers performed the experiment on two separate occasions (in their ON and OFF state). Freezers reported higher levels of anxiety compared to Non-Freezers (p < 0.001) and all patients reported greater levels of anxiety when walking across the HIGH plank compared to the LOW (p < 0.001). Freezers experienced significantly more freezing of gait episodes (p = 0.013) and spent a significantly greater percentage of each trial frozen (p = 0.005) when crossing the HIGH plank. This finding was even more pronounced when comparing Freezers in their OFF state. Freezers also had greater step length variability in the HIGH compared to the LOW condition, while the step length variability in Non-Freezers did not change. In conclusion, this was the first study to directly compare freezing of gait in anxious and non-anxious situations. These results present strong evidence that anxiety is an important mechanism underlying freezing of gait and supports the notion that the limbic system may have a profound contribution to freezing in PD.

Max Sandreczky: a pediatric surgeon in 19th-century Jerusalem.

PubMed

Nissan, S; Martin, P

1998-08-01

Until the mid-19th century, there had not been a single resident physician in the Holy Land. However, by the first World War in 1914, 19 hospitals had been established in Jerusalem. The reasons for this unusual phenomenon were religious, political, and sectarian. This does not apply to The Marienstift Kinderhospital, which was unique in 19th century Jerusalem. The hospital was founded and operated by Dr Max Sandreczky, a German pediatric surgeon. The standards of medical and surgical practice in the hospital not only compared favorably with those in western Europe, but, in certain aspects, they were more advanced. The Marienstift Kinderhospital was an "implant" of a western institution in a society that was medieval in character. The response of this society was studied as well as the natural history of this unique institution and its medical director, the pediatric surgeon, Dr Max Sandreczky.

The Bonn Astro/Geo Correlator

NASA Technical Reports Server (NTRS)

Bernhart, Simone; Alef, Walter; Bertarini, Alessandra; La Porta, Laura; Muskens, Arno; Rottmann, Helge; Roy, Alan

2013-01-01

The Bonn Distributed FX (DiFX) correlator is a software correlator operated jointly by the Max- Planck-Institut fur Radioastronomie (MPIfR), the Institut fur Geodasie und Geoinformation der Universitat Bonn (IGG), and the Bundesamt fur Kartographie und Geodasie (BKG) in Frankfurt.

Providing Database Services in a Nationwide Research Organisation--Coexistence of Traditional Information Services and a Modern CD-ROM/Online Hybrid Solution.

ERIC Educational Resources Information Center

Bowman, Benjamin F.

For the past two decades the central Information Retrieval Services of the Max Planck Society has been providing database searches for scientists in Max Planck Institutes and Research Groups throughout Germany. As a supplement to traditional search services offered by professional intermediaries, they have recently fostered the introduction of a…

Core Muscle Activity during TRX Suspension Exercises with and without Kinesiology Taping in Adults with Chronic Low Back Pain: Implications for Rehabilitation.

PubMed

Fong, Shirley S M; Tam, Y T; Macfarlane, Duncan J; Ng, Shamay S M; Bae, Young-Hyeon; Chan, Eleanor W Y; Guo, X

2015-01-01

This study aimed to examine the effects of kinesiology taping (KT) and different TRX suspension workouts on the amplitude of electromyographic (EMG) activity in the core muscles among people with chronic low back pain (LBP). Each participant (total n = 21) was exposed to two KT conditions: no taping and taping, while performing four TRX suspension exercises: (1) hamstring curl, (2) hip abduction in plank, (3) chest press, and (4) 45-degree row. Right transversus abdominis/internal oblique (TrAIO), rectus abdominis (RA), external oblique (EO), and superficial lumbar multifidus (LMF) activity was recorded with surface EMG and expressed as a percentage of the EMG amplitude recorded during a maximal voluntary isometric contraction of the respective muscles. Hip abduction in plank increased TrAIO, RA, and LMF EMG amplitude compared with other TRX positions (P < 0.008). Only the hamstring curl was effective in inducing a high EMG amplitude of LMF (P < 0.001). No significant difference in EMG magnitude was found between the taping and no taping conditions overall (P > 0.05). Hip abduction in plank most effectively activated abdominal muscles, whereas the hamstring curl most effectively activated the paraspinal muscles. Applying KT conferred no immediate benefits in improving the core muscle activation during TRX training in adults with chronic LBP.

Sport-specific endurance plank test for evaluation of global core muscle function.

PubMed

Tong, Tom K; Wu, Shing; Nie, Jinlei

2014-02-01

To examine the validity and reliability of a sports-specific endurance plank test for the evaluation of global core muscle function. Repeated-measures study. Laboratory environment. Twenty-eight male and eight female young athletes. Surface electromyography (sEMG) of selected trunk flexors and extensors, and an intervention of pre-fatigue core workout were applied for test validation. Intraclass correlation coefficient (ICC), coefficient of variation (CV), and the measurement bias ratio */÷ ratio limits of agreement (LOA) were calculated to assess reliability and measurement error. Test validity was shown by the sEMG of selected core muscles, which indicated >50% increase in muscle activation during the test; and the definite discrimination of the ∼30% reduction in global core muscle endurance subsequent to a pre-fatigue core workout. For test-retest reliability, when the first attempt of three repeated trials was considered as familiarisation, the ICC was 0.99 (95% CI: 0.98-0.99), CV was 2.0 ± 1.56% and the measurement bias ratio */÷ ratio LOA was 0.99 */÷ 1.07. The findings suggest that the sport-specific endurance plank test is a valid, reliable and practical method for assessing global core muscle endurance in athletes given that at least one familiarisation trial takes place prior to measurement. Copyright © 2013 Elsevier Ltd. All rights reserved.

Institutional Abuse: Understanding Domination from the Inside Looking Out.

ERIC Educational Resources Information Center

Jones, Jocelyn

1995-01-01

Applies a conceptual framework drawn from Max Weber's ideas of domination to examine the ways by which domination of child victims is created and maintained in cases of institutional abuse. Suggests that a solution is to regulate institutional abuse by written guidance on procedures, by frequent inspections, and through copious recommendations…

Cyclic voltammetry: a tool to quantify 2,4,6-trichloroanisole in aqueous samples from cork planks boiling industrial process.

PubMed

Peres, António M; Freitas, Patrícia; Dias, Luís G; Sousa, Mara E B C; Castro, Luís M; Veloso, Ana C A

2013-12-15

Chloroanisoles, namely 2,4,6-trichloroanisole, are pointed out as the primary responsible of the development of musty off-flavours in bottled wine, due to their migration from cork stoppers, which results in huge economical losses for wine industry. A prevention step is the detection of these compounds in cork planks before stoppers are produced. Mass spectrometry gas chromatography is the reference method used although it is far beyond economical possibilities of the majority of cork stoppers producers. In this work, a portable cyclic voltammetry approach was used to detect 2,4,6-trichloroanisole extracted from natural cork planks to the aqueous phase during the cork boiling industrial treatment process. Analyses were carried out under ambient conditions, in less than 15 min with a low use of solvent and without any sample pre-treatment. The proposed technique had detection (0.31±0.01 ng/L) and quantification (0.95±0.05 ng/L) limits lower than the human threshold detection level. For blank solutions, without 2,4,6-trichloroanisole addition, a concentration in the order of the quantification limit was estimated (1.0±0.2 ng/L), which confirms the satisfactory performance of the proposed methodology. For aqueous samples from the industrial cork planks boiling procedure, intra-day repeatabilities were lower than 3%, respectively. Also, 2,4,6-trichloroanisole contents in the aqueous samples determined by this novel approach were in good agreement with those obtained by GC-MS (correlation coefficient equal to 0.98), confirming the satisfactory accuracy of the proposed methodology. So, since this novel approach is a fast, low-cost, portable and user-friendly method, it can be an alternative and helpful tool for in-situ industrial applications, allowing accurate detection of releasable 2,4,6-trichloroanisole in an earlier phase of cork stoppers production, which may allow implementing more effective cork treatments to reduce or avoid future 2,4,6-trichloroanisole contaminations of wine. © 2013 Elsevier B.V. All rights reserved.

Assessing anxiety in Black men with prostate cancer: further data on the reliability and validity of the Memorial Anxiety Scale for Prostate Cancer (MAX-PC).

PubMed

Nelson, Christian J; Starr, Tatiana D; Macchia, Richard J; Hyacinthe, Llewellyn; Friedman, Steven; Roth, Andrew J

2016-07-01

The National Cancer Institute has highlighted the need for psychosocial research to focus on Black cancer patients. This applies to Black men with prostate cancer, as there is little systematic research concerning psychological distress in these men. This study was designed to validate the Memorial Anxiety Scale for Prostate Cancer (MAX-PC) in Black men with prostate cancer to help facilitate research within this group. At three institutions, Black men with prostate cancer (n = 101) completed the MAX-PC, the Hospital Anxiety and Depression Scale (HADS), the Functional Assessment of Cancer Therapy (FACT) Quality of Life Questionnaire, and the Distress Thermometer. The average age of the 101 men was 66 (SD = 10) and 58 % had early-stage disease. The MAX-PC and its subscales (Prostate Cancer Anxiety, PSA Anxiety, and Fear of Recurrence) produced strong coefficient alphas (0.89, 0.88, 0.71, and 0.77, respectively). Factor analysis supported the three-factor structure of the scale established in earlier findings. The MAX-PC also demonstrated strong validity. MAX-PC total scores correlated highly with the Anxiety subscale of the HADS (r = 0.59, p < 0.01) and the FACT Emotional Well-Being subscale (r = -0.55, p < 0.01). Demonstrating discriminant validity, the correlation with the HADS Depression subscale (r = 0.40, p < 0.01) and the CES-D (r = 0.42, p < 0.01) was lower compared to that with the HADS Anxiety subscale. The MAX-PC is valid and reliable in Black men with prostate cancer. We hope the validation of this scale in Black men will help facilitate psychosocial research in this group that is disproportionately adversely affected by this cancer.

11. Interior view, second floor, tin shop area looking southwest, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. Interior view, second floor, tin shop area looking southwest, showing laminated plank arched roof trusses. - Larrabee & Hingston Company, Main Shop Building, 19 Howley Street, Peabody, Essex County, MA

Quantification of Hydroxyl Radical reactivity in the urban environment using the Comparative Reactivity Method (CRM)

NASA Astrophysics Data System (ADS)

Panchal, Rikesh; Monks, Paul

2015-04-01

Hydroxyl (OH) radicals play an important role in 'cleansing' the atmosphere of many pollutants such as, NOx, CH4 and various VOCs, through oxidation. To measure the reactivity of OH, both the sinks and sources of OH need to be quantified, and currently the overall sinks of OH seem not to be fully constrained. In order to measure the total rate loss of OH in an ambient air sample, all OH reactive species must be considered and their concentrations and reaction rate coefficients with OH known. Using the method pioneered by Sinha and Williams at the Max Plank Institute Mainz, the Comparative Reactivity Method (CRM) which directly quantifies total OH reactivity in ambient air without the need to consider the concentrations of individual species within the sample that can react with OH, has been developed and applied in a urban setting. The CRM measures the concentration of a reactive species that is present only in low concentrations in ambient air, in this case pyrrole, flowing through a reaction vessel and detected using Proton Transfer Reaction - Mass Spectrometry (PTR-MS). The poster will show a newly developed and tested PTR-TOF-MS system for CRM. The correction regime will be detailed to account for the influence of the varying humidity between ambient air and clean air on the pyrrole signal. Further, examination of the sensitivity dependence of the PTR-MS as a function of relative humidity and H3O+(H2O) (m/z=37) cluster ion allows the correction for the humidity variation, between the clean humid air entering the reaction vessel and ambient air will be shown. NO, present within ambient air, is also a potential interference and can cause recycling of OH, resulting in an overestimation of OH reactivity. Tests have been conducted on the effects of varying NO concentrations on OH reactivity and a correction factor determined for application to data when sampling ambient air. Finally, field tests in the urban environment at the University of Leicester will be shown coupled to an examination of trends in OH reactivity and other air quality markers such NOx and black carbon.

Analysis decorating design on Perahu Buatan Barat, the Malay traditional boat by using frieze pattern

NASA Astrophysics Data System (ADS)

Wahab, Mohd Rohaizat Abdul; Ramli, Zuliskandar; Zakaria, Ros Mahwati Ahmad; Samad, Mohammad Anis Abdul

2017-01-01

Boat building tradition is one of the skills mastered by Malay craftsmen. Decoration on the Perahu Buatan Barat, the Malay traditional boat is one of the uniqueness of the production of traditional boats in East Coast of Malaysia. The tradition of Malay boat building, each plank was given specific names based on the line of planks. There is one line called `papan tarik' or `papan cantik' was usually decorated with paintings by a variety of motifs and patterns from the bow to the stern of the boat. The motifs usually taken from the surrounding environment as well as flora and fauna will be painted with motifs repeated but with differing formations. The aim of this study is to identify the motifs and analyze the formation of motifs by using mathematical methods of frieze pattern.

Electromyographic response of global abdominal stabilizers in response to stable- and unstable-base isometric exercise.

PubMed

Atkins, Stephen J; Bentley, Ian; Brooks, Darrell; Burrows, Mark P; Hurst, Howard T; Sinclair, Jonathan K

2015-06-01

Core stability training traditionally uses stable-base techniques. Less is known as to the use of unstable-base techniques, such as suspension training, to activate core musculature. This study sought to assess the neuromuscular activation of global core stabilizers when using suspension training techniques, compared with more traditional forms of isometric exercise. Eighteen elite level, male youth swimmers (age, 15.5 ± 2.3 years; stature, 163.3 ± 12.7 cm; body mass, 62.2 ± 11.9 kg) participated in this study. Surface electromyography (sEMG) was used to determine the rate of muscle contraction in postural musculature, associated with core stability and torso bracing (rectus abdominus [RA], external obliques [EO], erector spinae [ES]). A maximal voluntary contraction test was used to determine peak amplitude for all muscles. Static bracing of the core was achieved using a modified "plank" position, with and without a Swiss ball, and held for 30 seconds. A mechanically similar "plank" was then held using suspension straps. Analysis of sEMG revealed that suspension produced higher peak amplitude in the RA than using a prone or Swiss ball "plank" (p = 0.04). This difference was not replicated in either the EO or ES musculature. We conclude that suspension training noticeably improves engagement of anterior core musculature when compared with both lateral and posterior muscles. Further research is required to determine how best to activate both posterior and lateral musculature when using all forms of core stability training.

The temporal spectrum of the sdB pulsating star HS 2201+2610 at 2 ms resolution

NASA Astrophysics Data System (ADS)

Silvotti, R.; Janulis, R.; Schuh, S. L.; Charpinet, S.; Oswalt, T.; Silvestri, N.; Gonzalez Perez, J. M.; Kalytis, R.; Meištas, E.; Ališauskas, D.; Marinoni, S.; Jiang, X. J.; Reed, M. D.; Riddle, R. L.; Bernabei, S.; Heber, U.; Bärnbantner, O.; Cordes, O.; Dreizler, S.; Goehler, E.; Østensen, R.; Bochanski, J.; Carlson, G.

2002-07-01

In this article we present the results of more than 180 hours of time-series photometry on the low gravity (log g=5.4, Teff=29 300 K, log He/H=-3.0 by number) sdB pulsating star HS 2201+2610, obtained between September 2000 and August 2001. The temporal spectrum is resolved and shows 5 close frequencies: three main signals at 2860.94, 2824.10 and 2880.69 mu Hz, with amplitudes of about 1%, 0.5% and 0.1% respectively, are detected from single run observations; two further peaks with very low amplitude (<0.07%) at 2738.01 and 2921.82 mu Hz are confirmed by phase analysis on several independent runs. Due to the small number of detected frequencies, it is not possible to obtain a univocal identification of the excited modes and perform a detailed seismological analysis of the star. No clear signatures of rotational splitting are seen. Nevertheless, the observed period spectrum is well inside the excited period window obtained from pulsation calculations with nonadiabatic models having effective temperature and surface gravity close to the spectroscopic estimates. Due to its relatively simple temporal spectrum, HS 2201+2610 is a very good candidate for trying to measure the secular variation of the pulsation periods in time. With this purpose a long-term monitoring of the star was started. The results of the first 11 months show amplitude variations up to ~ 20% on time-scales of months, which are probably real, and allow us to measure the pulsation frequencies with an unprecedented 0.02 mu Hz resolution. Based on observations obtained at the following telescopes: Loiano 1.5 m (Bologna Astronomical Observatory), Moletai 1.65 m (Institute of Theoretical Physics and Astronomy, Vilnius), Calar Alto 2.2 and 1.2 m (German-Spanish Astronomical Center operated by the Max-Plank-Institute für Astronomie Heidelberg jointly with the Spanish National Commission for Astronomy), SARA 0.9 m (Southeastern Association for Research in Astronomy, at Kitt Peak, Arizona), Tenerife 0.8 m (Instituto de Astrofisica de Canarias), NOT 2.6 m (operated on the island of La Palma jointly by Denmark, Finland, Iceland, Norway, and Sweden, in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofisica de Canarias), Beijing 0.85 m (Beijing Astronomical Observatory), Fick 0.6 m (Iowa State University), Wendelstein 0.8 m (University of Munich).

Study Quantifies Physical Demands of Yoga in Seniors

MedlinePlus

... Z Study Quantifies Physical Demands of Yoga in Seniors Share: A recent NCCAM-funded study measured the ... performance of seven standing poses commonly taught in senior yoga classes: Chair, Wall Plank, Tree, Warrior II, ...

5. Typical plankcovered flume. View looks west near Luna de ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Typical plank-covered flume. View looks west near Luna de Miel Street. - Lake Hodges Flume, Along San Dieguito River between Lake Hodges & San Dieguito Reservoir, Rancho Santa Fe, San Diego County, CA

q-Deformed Minkowski Algebra and Its Space-Time Lattice

NASA Astrophysics Data System (ADS)

Wess, J.

2Max-Planck-Institut für Physik (Werner-Heisenberg-Institut) Föhringer Ring 6, D-80805 MünchenAbstract. We have asked how the Heisenberg relations of space and time change if we replace the Lorentz group by a q-deformed Lorentz group (Lorek et al. 1997).

An efficient, movable single-particle detector for use in cryogenic ultra-high vacuum environments.

PubMed

Spruck, Kaija; Becker, Arno; Fellenberger, Florian; Grieser, Manfred; von Hahn, Robert; Klinkhamer, Vincent; Novotný, Oldřich; Schippers, Stefan; Vogel, Stephen; Wolf, Andreas; Krantz, Claude

2015-02-01

A compact, highly efficient single-particle counting detector for ions of keV/u kinetic energy, movable by a long-stroke mechanical translation stage, has been developed at the Max-Planck-Institut für Kernphysik (Max Planck Institute for Nuclear Physics, MPIK). Both, detector and translation mechanics, can operate at ambient temperatures down to ∼10 K and consist fully of ultra-high vacuum compatible, high-temperature bakeable, and non-magnetic materials. The set-up is designed to meet the technical demands of MPIK's Cryogenic Storage Ring. We present a series of functional tests that demonstrate full suitability for this application and characterise the set-up with regard to its particle detection efficiency.

NASA/Max Planck Institute Barium Ion Cloud Project.

NASA Technical Reports Server (NTRS)

Brence, W. A.; Carr, R. E.; Gerlach, J. C.; Neuss, H.

1973-01-01

NASA and the Max Planck Institute for Extraterrestrial Physics (MPE), Munich, Germany, conducted a cooperative experiment involving the release and study of a barium cloud at 31,500 km altitude near the equatorial plane. The release was made near local magnetic midnight on Sept. 21, 1971. The MPE-built spacecraft contained a canister of 16 kg of Ba CuO mixture, a two-axis magnetometer, and other payload instrumentation. The objectives of the experiment were to investigate the interaction of the ionized barium cloud with the ambient medium and to deduce the properties of electric fields in the proximity of the release. An overview of the project is given to briefly summarize the organization, responsibilities, objectives, instrumentation, and operational aspects of the project.

Investigator profile. An interview with Russell D. Fernald, Ph.D. Interview by Vicki Glaser.

PubMed

Fernald, Russell D

2006-01-01

Russell D. Fernald, Ph.D., is a Professor of Biological Sciences and the Benjamin Scott Crocker Professor in Human Biology at Stanford University (California). He received his Bachelor's degree from Swarthmore College (Swarthmore, PA) and his Ph.D. from the University of Pennsylvania (Philadelphia). Dr. Fernald completed a postdoctoral fellowship with Dr. O. Creutzfeldt at the Max-Planck-Institute for Psychiatry, in Munich, Germany, and a postdoctoral fellowship with Dr. Konrad Lorenz at the Max-Planck-Institute for Behavioral Physiology. In 2004 he shared the Rank Prize for discoveries about lens function. Dr. Fernald's lab uses an African cichlid fish species to study how social experience influences the brain and how retinal progenitor cell division and differentiation are controlled.

PERSPECTIVE NORTHEAST. NOTE TYPICAL NEW HAMPSHIRE COVERED BRIDGE HOUSING, WITH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

PERSPECTIVE NORTHEAST. NOTE TYPICAL NEW HAMPSHIRE COVERED BRIDGE HOUSING, WITH UPPER PORTION OF TRUSSES LEFT EXPOSED AND VERTICAL PLANK SIDING COVERING THE LOWER PORTION. - Mechanic Street Bridge, Spanning Israel River, Lancaster, Coos County, NH

46 CFR 160.035-9 - Cubic capacity of lifeboats.

Code of Federal Regulations, 2010 CFR

2010-10-01

... lifeboats. (a) Definitions. The following definitions apply to the measurement of a lifeboat to determine... or planking at the stem to the corresponding position at the stern. In the case of a boat with a...

46 CFR 160.035-9 - Cubic capacity of lifeboats.

Code of Federal Regulations, 2011 CFR

2011-10-01

... lifeboats. (a) Definitions. The following definitions apply to the measurement of a lifeboat to determine... or planking at the stem to the corresponding position at the stern. In the case of a boat with a...

20. VIEW SOUTHEAST OF UPPER LEVEL (LUMBER STORAGE) IN EAST ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

20. VIEW SOUTHEAST OF UPPER LEVEL (LUMBER STORAGE) IN EAST BUILDING SHOWING BUILDING FRAMEWORK, IRON HANGING RODS, AND CEDAR PLANKS BEING SEASONED FOR BOAT CONSTRUCTION. - Lowell's Boat Shop, 459 Main Street, Amesbury, Essex County, MA

[A utopian episode - Carl Friedrich von Weizsäcker in the networks of the Max-Planck Society].

PubMed

Kant, Horst; Renn, Jürgen

2014-01-01

Carl Friedrich von Weizsäcker was a key figure in the history of the Max Planck Society (MPS). This essay contextualises his work with the development of the MPS, highlighting the institutional and personal networks upon which it was based. Some of the stations addressed in the following are his role in the German Uranium Project, in preparing the Mainau Declaration, the Göttingen Manifesto, and the Memorandum of Tübingen as well as his involvement in the foundation of the Max Planck Institute (MPI) for Human Development and his own MPI for the Research of Living Conditions in the Modern World located in Starnberg. The relationship between Weizsäcker and Hellmut Becker, long-time friend and founding director of the MPI for Human Development, will be of particular interest. Another issue broached here is the connection between natural science and the humanities in Weizsäcker's work, and subsequently the relation between these two science cultures in the MPS. Finally, we look at the challenges Weizsäcker's work could present to the MPS today.

Interior view, detail view in master bedroom looking northwest to ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Interior view, detail view in master bedroom looking northwest to show board & batten door opened to reveal original planks, with scale; note; nursery beyond door to west - Fort Hill, Clemson University Campus, Clemson, Pickens County, SC

19. DETAIL VIEW OF SKIFF BOW WITH OAK STEM AND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

19. DETAIL VIEW OF SKIFF BOW WITH OAK STEM AND FRAMES PLANKED IN CEDAR USING COPPER CLINCH NAILS. TRANSOM OF SECOND SKIFF CAN BE SEEN BACKGROUND. - Lowell's Boat Shop, 459 Main Street, Amesbury, Essex County, MA

NF1 Is an Effector and Regulator of the GPCR Signaling in the Nervous System

DTIC Science & Technology

2015-04-01

PRINCIPAL INVESTIGATOR: Kirill Martemyanov, Ph.D., Associate Professor CONTRACTING ORGANIZATION: The Scripps Research Institute – Florida Jupiter ...ADDRESS(ES) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER The Scripps Research Institute – Florida 130 Scripps Way Jupiter , FL 33458-5284...results stemming from this support during the following invited lectures: 09.2014 Max Planck Institute for Neuroscience, Jupiter , FL 09.2014

Max Wertheimer, Habilitation candidate at the Frankfurt Psychological Institute.

PubMed

Gundlach, Horst

2014-05-01

Max Wertheimer told Edwin B. Newman that it was pure chance that on his way to the Rhineland he prematurely got off the train in Frankfurt, and that he did so because he had an inspiration for an experiment that he wanted to perform. Most historians of psychology accept this anecdote, but fail to mention that thereby Wertheimer also mastered the next and decisive step toward his academic career in accomplishing his Habilitation. Exposing the institutional, personal, and intellectual context of Wertheimer's going to Frankfurt and giving a detailed account of the procedure of Habilitation will show that Newman's and similar reports of the episode, even if verbatim to Wertheimer's own telling, are nevertheless too improbable to accept at face value. PsycINFO Database Record (c) 2014 APA, all rights reserved.

THEMIS Art #137

NASA Image and Video Library

2017-06-30

This image captured by NASA's 2001 Mars Odyssey spacecraft looks a plank of wood, with a beautiful grain to it. Orbit Number: 64928 Latitude: -86.5268 Longitude: 158.521 Instrument: VIS Captured: 2016-08-02 23:46 https://photojournal.jpl.nasa.gov/catalog/PIA21696

Interior below decks in fish hold looking forward. Fish hatch ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Interior below decks in fish hold looking forward. Fish hatch opening is at upper left, ceiling planks and knees at center and right. - Purse Seiner SHENANDOAH, Gig Harbor Peninsula Historical Society and Museum, Gig Harbor, Pierce County, WA

Center for Adaptive Optics | Jobs

Science.gov Websites

, 2015 University of Geneva Adaptive Optics Scientist or Engineer March 16, 2015 NRC-Herzberg Astronomy Max Planck Institute for Astronomy (MPIA) Post-doctoral Fellowships in High-angular Resolution

Circular A-21: Cost Principles for Educational Institutions. NACUBO Special Report 79-4.

ERIC Educational Resources Information Center

National Association of College and University Business Officers, Washington, DC.

The Office of Management and Budget Circular A-21 on cost principles for educational institutions, which was published in the Federal Register on March 6, 1979, is reproduced in its entirety, and a brief introduction by Max A. Binkley is presented. The circular established principles for determining costs applicable to federal grants, contracts,…

Nonlinear Effects in High Electric Fields

DTIC Science & Technology

1993-04-06

ion microscope above protruding atoms. Experiments to verify our theoret- ical predictions have been performed at the Fritz - Haber -Institute, see...Block’s experimental group at the Fritz - Haber -Institut in Berlin. A recent topic was thermal field desorption of hydrogen for which we have been able...Suchorskil, W. A. Schmidt’, J. H. Block’ and H. J. Kreuzer2 To be published in Surface Science ’Fitz- Haber Institut der Max-Planck-Gesellschaft

29 CFR 1926.855 - Manual removal of floors.

Code of Federal Regulations, 2011 CFR

2011-07-01

... floor arch, debris and other material shall be removed from such arch and other adjacent floor area... collapse. The open space between planks shall not exceed 16 inches. (c) Safe walkways, not less than 18... cleared of debris and any other unnecessary materials. ...

29 CFR 1926.855 - Manual removal of floors.

Code of Federal Regulations, 2012 CFR

2012-07-01

... floor arch, debris and other material shall be removed from such arch and other adjacent floor area... collapse. The open space between planks shall not exceed 16 inches. (c) Safe walkways, not less than 18... cleared of debris and any other unnecessary materials. ...

29 CFR 1926.855 - Manual removal of floors.

Code of Federal Regulations, 2013 CFR

2013-07-01

... floor arch, debris and other material shall be removed from such arch and other adjacent floor area... collapse. The open space between planks shall not exceed 16 inches. (c) Safe walkways, not less than 18... cleared of debris and any other unnecessary materials. ...

29 CFR 1926.855 - Manual removal of floors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... floor arch, debris and other material shall be removed from such arch and other adjacent floor area... collapse. The open space between planks shall not exceed 16 inches. (c) Safe walkways, not less than 18... cleared of debris and any other unnecessary materials. ...

Identification of selected CITES-protected Araucariaceae using DART TOFMS

Treesearch

Philip D. Evans; Ignacio A. Mundo; Michael C. Wiemann; Gabriela D. Chavarria; Pamela J. McClure; Doina Voin; Edgard O. Espinoza

2017-01-01

Determining the species source of logs and planks suspected of being Araucaria araucana (Molina) K.Koch (CITES Appendix I) using traditional wood anatomy has been difficult, because its anatomical features are not diagnostic. Additionally, anatomical studies of Araucaria angustifolia (Bertol.) Kuntze, Araucaria...

29 CFR 1926.855 - Manual removal of floors.

Code of Federal Regulations, 2014 CFR

2014-07-01

... floor arch, debris and other material shall be removed from such arch and other adjacent floor area... collapse. The open space between planks shall not exceed 16 inches. (c) Safe walkways, not less than 18... cleared of debris and any other unnecessary materials. ...

A spot check for assessing static orientation consistency of inertial and magnetic sensing units.

PubMed

Picerno, Pietro; Cereatti, Andrea; Cappozzo, Aurelio

2011-03-01

Despite the widespread use of Magnetic and Inertial Measurement Units (MIMUs) for movement reconstruction, only a few studies have tackled issues related to their accuracy. It has been proved that their performance decreases over a period of use since calibration parameters become no longer effective. Good practice rules recommend to assess, prior to any experimental session, the instrumental errors associated to the relevant measures. Aim of this study was to provide a practical and reproducible spot check for assessing the performance of MIMUs in terms of consistency in determining their orientation with respect to a common (inter-MIMUs consistency, IC) and invariant (self-MIMU consistency, SC) global frame. IC was assessed by verifying the hypothesis that the orientation of 9 MIMUs aligned to each other on a rigid Plexiglas plank coincided at any orientation of the plank. SC was assessed separately by verifying differences between measured and imposed known rotations imparted to each MIMU. The orientation of MIMUs relative to the global frame was expressed in terms of quaternion. IC test showed that MIMUs defined their orientation differently. This difference was not constant but varied according to the plank's orientation. The least consistent MIMU showed discrepancy up to 5.7°. SC test confirmed the same MIMU as that affected by the highest inaccuracy (8.4°), whereas it revealed errors within limits (1°) in correspondence to other MIMUs. A tool has been proposed that allows the users to be aware of the errors that may be expected when using MIMUs for the estimate of absolute and relative segments kinematics. Copyright © 2010 Elsevier B.V. All rights reserved.

22. VIEW ACROSS UPPER LEVEL OF EAST BUILDING TOWARDS THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. VIEW ACROSS UPPER LEVEL OF EAST BUILDING TOWARDS THE SOUTH (RIVER) SHOWING ROOF TRUSSES, PLANK AND PATTERN STORAGE, HINGED ACCESS HATCH TO STREET LEVEL SHOP CAN BE SEEN OPENED IN FOREGROUND. - Lowell's Boat Shop, 459 Main Street, Amesbury, Essex County, MA

Throw away the Fish, Eat the Plank: Developing the Writer through the Text.

ERIC Educational Resources Information Center

Hynds, Susan

1988-01-01

Argues that teachers of writing are more concerned about good writing than about good writers, and that they should instead strive to improve the experience of writing, even if that means throwing out the piece of writing produced. (JAD)

13. VIEW SHOWING MOST OF THE PERIMETER FROM SPILLWAY BOX ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. VIEW SHOWING MOST OF THE PERIMETER FROM SPILLWAY BOX TO END OF EAST DAM. FOREGROUND VIEW SHOWS TRIPLE WALL CONSTRUCTION OF TONGUE AND GROOVE PLANKING USED IN CRIBBING - Three Bears Lake & Dams, North of Marias Pass, East Glacier Park, Glacier County, MT

One hundred years of the Fritz Haber Institute.

PubMed

Friedrich, Bretislav; Hoffmann, Dieter; James, Jeremiah

2011-10-17

We outline the institutional history and highlight aspects of the scientific history of the Fritz Haber Institute (FHI) of the Max Planck Society, successor to the Kaiser Wilhelm Institute for Physical Chemistry and Electrochemistry, from its founding in 1911 until about the turn of the 21st century. Established as one of the first two Kaiser Wilhelm Institutes, the Institute began as a much-awaited remedy for what prominent German chemists warned was the waning of Germany's scientific and technological superiority relative to the United States and to other European nations. The history of the Institute has largely paralleled that of 20th century Germany. It spearheaded the research and development of chemical weapons during World War I, then experienced a "golden era" during the 1920s and early 1930s, in spite of financial hardships. Under the National Socialists it suffered a purge of its scientific staff and a diversion of its research into the service of the new regime, accompanied by a breakdown in its international relations. In the immediate aftermath of World War II it suffered crippling material losses, from which it recovered slowly in the postwar era. In 1952, the Institute took the name of its founding director and the following year joined the fledgling Max Planck Society, successor to the Kaiser Wilhelm Society. During the 1950s and 1960s, the Institute supported diverse research into the structure of matter and electron microscopy in its geographically isolated and politically precarious location in West Berlin. In subsequent decades, as Berlin benefited from the policies of détente and later glasnost and the Max Planck Society continued to reassess its preferred model of a research institute, the FHI reorganized around a board of coequal scientific directors and renewed its focus on the investigation of elementary processes on surfaces and interfaces, topics of research that had been central to the work of Fritz Haber and the first "golden era" of the Institute. Throughout its one-hundred-year history, the Institute's pace-setting research has been shaped by dozens of distinguished scientists, among them seven Nobel laureates. Here we highlight the contributions made at the Institute to the fields of gas-phase kinetics and dynamics, early quantum physics, colloid chemistry, electron microscopy, and surface chemistry, and we give an account of the key role the Institute played in implementing the Berlin Electron Synchrotron (BESSY I and II). Current research at the Institute in surface science and catalysis as well as molecular physics and spectroscopy is exemplified in this issue [Angew. Chem. 2011, 123, 10242; Angew. Chem. Int. Ed. 2011, 50, 10064]. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Improved diffusion Monte Carlo propagators for bosonic systems using Itô calculus

NASA Astrophysics Data System (ADS)

Hâkansson, P.; Mella, M.; Bressanini, Dario; Morosi, Gabriele; Patrone, Marta

2006-11-01

The construction of importance sampled diffusion Monte Carlo (DMC) schemes accurate to second order in the time step is discussed. A central aspect in obtaining efficient second order schemes is the numerical solution of the stochastic differential equation (SDE) associated with the Fokker-Plank equation responsible for the importance sampling procedure. In this work, stochastic predictor-corrector schemes solving the SDE and consistent with Itô calculus are used in DMC simulations of helium clusters. These schemes are numerically compared with alternative algorithms obtained by splitting the Fokker-Plank operator, an approach that we analyze using the analytical tools provided by Itô calculus. The numerical results show that predictor-corrector methods are indeed accurate to second order in the time step and that they present a smaller time step bias and a better efficiency than second order split-operator derived schemes when computing ensemble averages for bosonic systems. The possible extension of the predictor-corrector methods to higher orders is also discussed.

Progress with the COGENT Edge Kinetic Code: Implementing the Fokker-Plank Collision Operator

DOE PAGES

Dorf, M. A.; Cohen, R. H.; Dorr, M.; ...

2014-06-20

Here, COGENT is a continuum gyrokinetic code for edge plasma simulations being developed by the Edge Simulation Laboratory collaboration. The code is distinguished by application of a fourth-order finite-volume (conservative) discretization, and mapped multiblock grid technology to handle the geometric complexity of the tokamak edge. The distribution function F is discretized in v∥ – μ (parallel velocity – magnetic moment) velocity coordinates, and the code presently solves an axisymmetric full-f gyro-kinetic equation coupled to the long-wavelength limit of the gyro-Poisson equation. COGENT capabilities are extended by implementing the fully nonlinear Fokker-Plank operator to model Coulomb collisions in magnetized edge plasmas.more » The corresponding Rosenbluth potentials are computed by making use of a finite-difference scheme and multipole-expansion boundary conditions. Details of the numerical algorithms and results of the initial verification studies are discussed. (© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)« less

The Pan-STARRS1 Surveys

NASA Astrophysics Data System (ADS)

Chambers, Kenneth C.

2014-01-01

Pan-STARRS1 is approaching the completion of the PS1 Science Mission. Operations of the PS1 System include the Observatory, Telescope, 1.4 Gigapixel Camera, Image Processing Pipeline , PSPS relational database and reduced science product software servers. The Pan-STARRS1 Surveys include: (1) A 3pi Steradian Survey, (2) A Medium Deep survey of 10 PS1 footprints spaced around the sky; (3) A solar system survey optimized for Near Earth Objects, (4) a Stellar Transit Survey; and (5) a Deep Survey of M31. The PS1 3pi Survey has now covered the sky north of dec=-30 with more than 12 visits in five bands: g,r,i,z and y or over ~60 epochs per 0.25 arcsec resolution element on the sky. The performance of the PS1 system, sky coverage, cadence, and data quality of the Pan-STARRS1 Surveys will be presented as well as progress in reprocessing of the data taken to date and the plans for the public release of all Pan-STARRS1 data products in the spring of 2015. The Pan-STARRS1 Surveys (PS1) have been made possible through contributions of the Institute for Astronomy, the University of Hawaii, the Pan-STARRS Project Office, the Max-Planck Society and its participating institutes, the Max Planck Institute for Astronomy, Heidelberg and the Max Planck Institute for Extraterrestrial Physics, Garching, The Johns Hopkins University, Durham University, the University of Edinburgh, Queen's University Belfast, the Harvard-Smithsonian Center for Astrophysics, the Las Cumbres Observatory Global Telescope Network Incorporated, the National Central University of Taiwan, the Space Telescope Science Institute, the National Aeronautics and Space Administration under Grant No. NNX08AR22G issued through the Planetary Science Division of the NASA Science Mission Directorate, the National Science Foundation under Grant No. AST-1238877, the University of Maryland, and Eotvos Lorand University (ELTE).

The Pan-STARRS1 Survey Data Release

NASA Astrophysics Data System (ADS)

Chambers, Kenneth C.; Pan-STARRS Team

2017-01-01

The first Pan-STARRS1 Science Mission is complete and an initial Data Release 1, or DR1, including a database of measured attributes, stacked images, and metadata of the 3PI Survey, will be available from the STScI MAST archive. This release will contain all stationary objects with mean and stack photometry registered on the GAIA astrometric frame.The characteristics of the Pan-STARRS1 Surveys will be presented, including image quality, depth, cadence, and coverage. Measured attributes include PSF model magnitudes, aperture magnitudes, Kron Magnitudes, radial moments, Petrosian magnitudes, DeVaucoulers, Exponential, and Sersic magnitudes for extended objects. Images include total intensity, variance, and masks.An overview of both DR1 and the second data release DR2, to follow in the spring of 2017, will be presented. DR2 will add all time domain data and individual warped images. We will also report on the status of the Pan-STARRS2 Observatory and ongoing science with Pan-STARRS. The science from the PS1 surveys has included results in many t fields of astronomy from Near Earth Objects to cosmology.The Pan-STARRS1 Surveys have been made possible through contributions of the Institute for Astronomy of the University of Hawaii; the Pan-STARRS Project Office; the Max-Planck Society and its participating institutes: the Max Planck Institute for Astronomy, Heidelberg and the Max Planck Institute for Extraterrestrial Physics, Garching; The Johns Hopkins University; Durham University; the University of Edinburgh; Queen's University Belfast; the Harvard-Smithsonian Center for Astrophysics, the Las Cumbres Observatory Global Telescope Network Incorporated; the National Central University of Taiwan; the Space Telescope Science Institute; the National Aeronautics and Space Administration under Grants No. NNX08AR22G, NNX12AR65G, NNX14AM74G issued through the Planetary Science Division of the NASA Science Mission Directorate; the National Science Foundation under Grant No. AST-1238877; the University of Maryland; the Eotvos Lorand University; and the Los Alamos National Laboratory.

Knowledge and Social Relationships in Teacher Education.

ERIC Educational Resources Information Center

Bell, Adrian

1981-01-01

Based on Max Weber's three ideal types of education (charismatic education, education of the cultivated man, and specialized expert training), the article analyzes interpersonal interaction and students' educational identities in teacher training institutions in Britain. (DB)

Epidemic classification of phytosanitary situations on cereal crops using mathematical modeling

USDA-ARS?s Scientific Manuscript database

Most plant protection researchers and experts divide emerging phytosanitary situations into three classes: epidemic, moderate development of disease, and yield depression. The known principles and methods for estimating these situations (Van der Plank J.E., Kranz J. et al.) do not fully describe th...

Relay cropping of wheat (Triticum aestivum L.) in cotton (Gossypium hirsutum L.) improves the profitability of cotton-wheat cropping system in Punjab, Pakistan.

PubMed

Sajjad, Aamer; Anjum, Shakeel Ahmad; Ahmad, Riaz; Waraich, Ejaz Ahmad

2018-01-01

Delayed sowing of wheat (Triticum aestivum L.) in cotton-based system reduces the productivity and profitability of the cotton-wheat cropping system. In this scenario, relay cropping of wheat in standing cotton might be a viable option to ensure the timely wheat sowing with simultaneous improvement in wheat yields and system profitability. This 2-year study (2012-2013 and 2013-2014) aimed to evaluate the influence of sowing dates and relay cropping combined with different management techniques of cotton sticks on the wheat yield, soil physical properties, and the profitability of the cotton-wheat system. The experiment consisted of five treatments viz. (S1) sowing of wheat at the 7th of November by conventional tillage (two disc harrows + one rotavator + two plankings) after the removal of cotton sticks, (S2) sowing of wheat at the 7th of November by conventional tillage (two disc harrows + two plankings) after the incorporation of cotton sticks in the field with a rotavator, (S3) sowing of wheat at the 7th of November as relay crop in standing cotton with broadcast method, (S4) sowing of wheat at the 15th of December by conventional tillage (two disc harrows + one rotavator + two plankings) after the removal of cotton sticks, and (S5) sowing of wheat at the 15th of December by conventional tillage (two disc harrows + two plankings) after the incorporation of cotton sticks in the field with a rotavator. The highest seed cotton yield was observed in the S5 treatment which was statistically similar with the S3 and S4 treatments; seed cotton yield in the S1 and S2 treatments has been the lowest in both years of experimentation. However, the S2 treatment produced substantially higher root length, biological yield, and grain yield of wheat than the other treatments. The lower soil bulk density at 0-10-cm depth was recorded in the S2 treatment which was statistically similar with the S5 treatment during both years of experimentation. The volumetric water contents, net benefit, and benefit-cost ratio were the highest in the S3 treatment during both years of experimentation. Thus, relay cropping of wheat in standing cotton might be a viable option to improve the soil physical environment and profitability of the cotton-wheat cropping system.

Cure of tuberculosis despite serum concentrations of antituberculosis drugs below published reference ranges.

PubMed

Meloni, Monica; Corti, Natascia; Müller, Daniel; Henning, Lars; Gutteck, Ursula; von Braun, Amrei; Weber, Rainer; Fehr, Jan

2015-01-01

Therapeutic target serum concentrations of first-line antituberculosis drugs have not been well defined in clinical studies in tuberculosis (TB) patients. We retrospectively investigated the estimated maximum serum concentrations (eC max) of antituberculosis drugs and clinical outcome of TB patients with therapeutic drug monitoring performed between 2010-2012 at our institution, and follow-up until March 2014. The eC max was defined as the highest serum concentration during a sampling period (2, 4 and 6 hours after drug ingestion). We compared the results with published eC max values, and categorised them as either "within reference range", "low eC max", or "very low eC max".Low/very low eC max-levels were defined as follows: isoniazid 2-3/<2 mg/l, rifampicin 4-8/<4 mg/l, rifabutin 0.2-0.3/<0.2 mg/l, ethambutol 1-2/<0.1 mg/l and pyrazinamide <20 mg/l. Concentrations of antituberculosis drugs in 175 serum samples of 17 patients with TB were analysed. In 12 (71%) patients, multiple therapeutic drug monitoring samples were collected over time, in 5 (29%) patients only one sample was available for therapeutic drug monitoring. Overall, 94% of all patients had at least one low antituberculosis drug concentration. Overall, 64% of all eC max levels were classified as "low" or "very low". The eC max was below the relevant reference range in 80% of isoniazid, 95% of rifampicin, 30% of pyrazinamide, and 30% of ethambutol measurements. All but one patient were cured of tuberculosis. Although many antituberculosis drug serum concentrations were below the widely used reference ranges, 16 of 17 patients were cured of tuberculosis. These results challenge the use of the published reference ranges for therapeutic drug monitoring.

Solar Observations on Magneto-Convection

DTIC Science & Technology

1989-05-31

Technical Library National Solar Observatory Sunspot, NM 88349 Karl - Schwarzschild -Strasse 1 8046 Garching bei Mundhen Solar Observations On Magneto...Schmidt, Hermann-Ulrich Schmidt, Hans-Christoph Thomas (eds.) Max-Planck-Institut fir Physik und Astrophysik Institut fiur Astrophysik Karl ... Schwarzschild -St-. 1 D-8046 Garching, FklG 14TIS CRiA.&l DTIC TA. U~Jar,iou8:ed B ......... ... Distribution I -- Availability COcý----- Avail and or Dist special

Forensic Analysis of Cites-Protected Dalbergia Timber from the Americas

Treesearch

Edgard O. Espinoza; Michael C. Wiemann; Josefina Barajas-Morales; Gabriela D. Chavarria; Pamela J. McClure

2015-01-01

Species identification of logs, planks, and veneers is difficult because they lack the traditional descriptors such as leaves and flowers. An additional challenge is that many transnational shipments have unreliable geographic provenance. Therefore, frequently the lowest taxonomic determination is genus, which allows unscrupulous importers to evade the endangered...

Steps to Take with the Board to Avoid Walking the Plank.

ERIC Educational Resources Information Center

Papallo, William R.

1990-01-01

A veteran superintendent outlines an eight-step method for achieving success, including assessing the situation, avoiding board overload, coping with stress, deemphasizing egoism, learning to live in the gray zone between policy formation and administration, ensuring effective board decisions, identifying prospective board members, and knowing…

REACTIVITY MEASUREMENT FACILITY, UNDER CONSTRUCTION OVER MTR CANAL IN BASEMENT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

REACTIVITY MEASUREMENT FACILITY, UNDER CONSTRUCTION OVER MTR CANAL IN BASEMENT OF MTR BUILDING, TRA-603. WOOD PLANKS REST ON CANAL WALL OBSERVABLE IN FOREGROUND. INL NEGATIVE NO. 11745. Unknown Photographer, 8/20/1954 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

23. VIEW DOWN INTO LAUNCHER AND FLAME BUCKET FROM STATION ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. VIEW DOWN INTO LAUNCHER AND FLAME BUCKET FROM STATION 48 IN SLC-3W MST. NOTE REMOVABLE METAL PLANKS BELOW LAUNCHER AND ROPE NET OVER FLAME BUCKET. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

78 FR 35950 - Federal Property Suitable as Facilities To Assist the Homeless

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-14

... yrs. vacant Virginia Tract 03-183 Dent House 9325 Pland Road Spotsylvania VA 22553 Landholding Agency... interior for more info. 03-181; Dulin House 9401 Plank Road Spotsvania VA 22553 Landholding Agency... & no piping; contact interior for more into. Tract 02-103 Richardson House 700 Sunken Road...

49 CFR 229.65 - Spring rigging.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Spring rigging. 229.65 Section 229.65....65 Spring rigging. (a) Protective construction or safety hangers shall be provided to prevent spring planks, spring seats or bolsters from dropping to track structure in event of a hanger or spring failure...

49 CFR 229.65 - Spring rigging.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Spring rigging. 229.65 Section 229.65....65 Spring rigging. (a) Protective construction or safety hangers shall be provided to prevent spring planks, spring seats or bolsters from dropping to track structure in event of a hanger or spring failure...

49 CFR 229.65 - Spring rigging.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Spring rigging. 229.65 Section 229.65....65 Spring rigging. (a) Protective construction or safety hangers shall be provided to prevent spring planks, spring seats or bolsters from dropping to track structure in event of a hanger or spring failure...

49 CFR 229.65 - Spring rigging.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Spring rigging. 229.65 Section 229.65....65 Spring rigging. (a) Protective construction or safety hangers shall be provided to prevent spring planks, spring seats or bolsters from dropping to track structure in event of a hanger or spring failure...

49 CFR 229.65 - Spring rigging.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Spring rigging. 229.65 Section 229.65....65 Spring rigging. (a) Protective construction or safety hangers shall be provided to prevent spring planks, spring seats or bolsters from dropping to track structure in event of a hanger or spring failure...

30 CFR 75.205 - Installation of roof support using mining machines with integral roof bolters.

Code of Federal Regulations, 2010 CFR

2010-07-01

... feet or more apart shall be installed with a wooden crossbar at least 3 inches thick and 8 inches wide... less than 9 feet apart shall be installed with a wooden plank at least 2 inches thick and 8 inches wide...

List of Participants

NASA Astrophysics Data System (ADS)

2008-11-01

Mohab Abou ZeidInstitut des Hautes Études Scientifiques, Bures-sur-Yvette Ido AdamMax-Planck-Institut für Gravitationsphysik (AEI), Potsdam Henrik AdorfLeibniz Universität Hannover Mohammad Ali-AkbariIPM, Tehran Antonio Amariti Università di Milano-Bicocca Nicola Ambrosetti Université de Neuchâtel Martin Ammon Max-Planck-Institut für Physik, München Christopher AndreyÉcole Polytechnique Fédérale de Lausanne (EPFL) Laura AndrianopoliPolitecnico di Torino David AndriotLPTHE, Université UPMC Paris VI Carlo Angelantonj Università di Torino Pantelis ApostolopoulosUniversitat de les Illes Balears, Palma Gleb ArutyunovInstitute for Theoretical Physics, Utrecht University Davide AstolfiUniversità di Perugia Spyros AvramisUniversité de Neuchâtel Mirela BabalicChalmers University, Göteborg Foday BahDigicom Ioannis Bakas University of Patras Igor BandosUniversidad de Valencia Jose L F BarbonIFTE UAM/CSIC Madrid Till BargheerMax-Planck-Institut für Gravitationsphysik (AEI), Potsdam Marco Baumgartl Eidgenössische Technische Hochschule (ETH), Zürich James BedfordImperial College London Raphael BenichouLaboratoire de Physique Théorique, École Normale Supérieure, Paris Francesco Benini SISSA, Trieste Eric Bergshoeff Centre for Theoretical Physics, University of Groningen Alice BernamontiVrije Universiteit, Brussel Julia BernardLaboratoire de Physique Théorique, École Normale Supérieure, Paris Adel Bilal Laboratoire de Physique Théorique, École Normale Supérieure, Paris Marco Billo' Università di Torino Matthias Blau Université de Neuchâtel Guillaume BossardAlbert-Einstein-Institut, Golm Leonardo BriziÉcole Polytechnique Fédérale de Lausanne (EPFL) Johannes BroedelLeibniz Universität Hannover (AEI) Tom BrownQueen Mary, University of London Ilka BrunnerEidgenössische Technische Hochschule (ETH), Zürich Erling BrynjolfssonUniversity of Iceland Dmitri BykovSteklov Institute, Moscow and Trinity College, Dublin Joan CampsUniversitat de Barcelona Davide CassaniLaboratoire de Physique Théorique, École Normale Supérieure, Paris Alejandra CastroUniversity of Michigan Claudio Caviezel Max-Planck-Institut für Physik, München Alessio Celi Universitat de Barcelona Anna Ceresole Istituto Nazionale di Fisica Nucleare, Università di Torino Athanasios ChatzistavrakidisNational Technical University of Athens Wissam ChemissanyCentre for Theoretical Physics, University of Groningen Eugen-Mihaita CioroianuUniversity of Craiova Andres CollinucciTechnische Universität Wien Paul CookUniversità di Roma, Tor Vergata Lorenzo CornalbaUniversità di Milano-Bicocca Aldo CotroneKatholieke Universiteit Leuven Ben Craps Vrije Universiteit, Brussel Stefano Cremonesi SISSA, Trieste Riccardo D'AuriaPolitecnico di Torino Gianguido Dall'AgataUniversity of Padova Jose A de AzcarragaUniversidad de Valencia Jan de BoerInstituut voor Theoretische Fysica, Universiteit van Amsterdam Sophie de BuylInstitut des Hautes Études Scientifiques, Bures-sur-Yvette Marius de LeeuwUtrecht University Frederik De RooVrije Universiteit, Brussel Jan De Rydt Katholieke Universiteit Leuven and CERN, Geneva Bernard de WitInstitute for Theoretical Physics, Utrecht University Stephane DetournayIstituto Nazionale di Fisica Nucleare, Sezione di Milano Paolo Di Vecchia Niels Bohr Institute, København Eugen DiaconuUniversity of Craiova Vladimir Dobrev Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, Sofia Nick DoreyUniversity of Cambridge Hajar Ebrahim NajafabadiIPM, Tehran Federico Elmetti Università di Milano Oleg Evnin Vrije Universiteit, Brussel Francesco Fiamberti Università di Milano Davide Forcella SISSA, Trieste and CERN, Geneva Valentina Forini Humboldt-Universität zu Berlin Angelos Fotopoulos Università di Torino Denis Frank Université de Neuchâtel Marialuisa Frau Università di Torino Matthias Gaberdiel Eidgenössische Technische Hochschule (ETH), Zürich Diego Gallego SISSA/ISAS, Trieste Maria Pilar Garcia del MoralIstituto Nazionale di Fisica Nucleare, Università di Torino Valentina Giangreco Marotta PulettiUppsala University Valeria L GiliQueen Mary, University of London Luciano GirardelloUniversità di Milano-Bicocca Gian GiudiceCERN, Geneva Kevin Goldstein Institute for Theoretical Physics, Utrecht University Joaquim Gomis Universitat de Barcelona Pietro Antonio GrassiUniversità del Piemonte Orientale, Alessandria Viviane GraßLudwig-Maximilians-Universität, München Gianluca Grignani Università di Perugia Luca Griguolo Università di Parma Johannes GrosseJagiellonian University, Krakow Umut Gursoy École Polytechnique, Palaiseau Norberto Gutierrez RodriguezUniversity of Oviedo Babak HaghighatPhysikalisches Institut, Universität Bonn Troels Harmark Niels Bohr Institute, København Robert HaslhoferEidgenössische Technische Hochschule (ETH), Zürich Tae-Won HaPhysikalisches Institut, Universität Bonn Alexander HauptImperial College London and Max-Planck-Institut für Gravitationsphysik (AEI), Potsdam Marc HenneauxUniversité Libre de Bruxelles Johannes HennLAPTH, Annecy-le-Vieux Shinji HiranoNiels Bohr Institute, København Stefan HoheneggerEidgenössische Technische Hochschule (ETH), Zürich Jan HomannLudwig-Maximilians-Universität, München Gabriele Honecker CERN, Geneva Joost HoogeveenInstituut voor Theoretische Fysica, Universiteit van Amsterdam Mechthild HuebscherUniversidad Autónoma de Madrid Chris HullImperial College London Carmen-Liliana IonescuUniversity of Craiova Ella JasminUniversité Libre de Bruxelles Konstantin KanishchevInstitute of Theoretical Physics, University of Warsaw Stefanos Katmadas Utrecht University Alexandros KehagiasNational Technical University of Athens Christoph Keller Eidgenössische Technische Hochschule (ETH), Zürich Patrick Kerner Max-Planck-Institut für Physik, München Rebiai KhaledLaboratoire de Physique Mathématique et Physique Subatomique, Université Mentouri, Constantine Elias Kiritsis Centre de Physique Théorique, École Polytechnique, Palaiseau and University of Crete Denis KleversPhysikalisches Institut, Universität Bonn Paul Koerber Max-Planck-Institut für Physik, München Simon Koers Max-Planck-Institut für Physik, München Karl KollerLudwig-Maximilians-Universität, München Peter Koroteev Institute for Theoretical and Experimental Physics (ITEP), Moscow and Max-Planck-Institut für Gravitationsphysik (AEI), Potsdam Alexey KoshelevVrije Universiteit, Brussel Costas KounnasÉcole Normale Supérieure, Paris Daniel KreflCERN, Geneva Charlotte KristjansenNiels Bohr Institute, København Finn LarsenCERN, Geneva and University of Michigan Arnaud Le DiffonÉcole Normale Supérieure, Lyon Michael LennekCentre de Physique Théorique, École Polytechnique, Palaiseau Alberto Lerda Università del Piemonte Orientale, Alessandria Andreas LiberisUniversity of Patras Maria A Lledo Universidad de Valencia Oscar Loaiza-Brito CINVESTAV, Mexico Florian Loebbert Max-Planck-Institut für Gravitationsphysik (AEI), Potsdam Yolanda Lozano University of Oviedo Dieter Luest Ludwig-Maximilians-Universität, München Tomasz Łukowski Jagiellonian University, Krakow Diego Mansi University of Crete Alberto Mariotti Università di Milano-Bicocca Raffaele Marotta Istituto Nazionale di Fisica Nucleare, Napoli Alessio Marrani Istituto Nazionale di Fisica Nucleare and LNF, Firenze Andrea Mauri University of Crete Liuba Mazzanti École Polytechnique, Palaiseau Sean McReynoldsUniversità di Milano-Bicocca AKM Moinul Haque Meaze Chittagong University Patrick Meessen Instituto de Física Teórica, Universidad Autónoma de Madrid Carlo MeneghelliUniversità di Parma and Albert-Einstein-Institut, Golm Lotta Mether University of Helsinki and CERN, Geneva René Meyer Max-Planck-Institut für Physik, München Georgios MichalogiorgakisCenter de Physique Théorique, École Polytechnique, Palaiseau Giuseppe Milanesi Eidgenössische Technische Hochschule (ETH), Zürich Samuel Monnier Université de Genève Wolfgang MueckUniversità di Napoli Federico II Elena Méndez Escobar University of Edinburgh Iulian Negru University of Craiova Emil NissimovInstitute for Nuclear Research and Nuclear Energy, Sofia Teake NutmaCentre for Theoretical Physics, University of Groningen Niels Obers Niels Bohr Institute, København Olof Ohlsson SaxUppsala University Rodrigo OleaIstituto Nazionale di Fisica Nucleare, Sezione di Milano Domenico OrlandoUniversité de Neuchâtel Marta Orselli Niels Bohr Institute, København Tomas OrtinInstituto de Física Teórica, Universidad Autónoma de Madrid Yaron OzTel Aviv University Enrico PajerLudwig-Maximilians-Universität, München Angel Paredes GalanUtrecht University Sara PasquettiUniversité de Neuchâtel Silvia PenatiUniversità di Milano-Bicocca Jan PerzKatholieke Universiteit Leuven Igor PesandoUniversità di Torino Tassos PetkouUniversity of Crete Marios PetropoulosCenter de Physique Théorique, École Polytechnique, Palaiseau Franco PezzellaIstituto Nazionale di Fisica Nucleare, Sezione di Napoli Moises Picon PonceUniversity of Padova Marco PirroneUniversità di Milano-Bicocca Andrea PrinslooUniversity of Cape Town Joris RaeymaekersKatholieke Universiteit Leuven Alfonso RamalloUniversidade de Santiago de Compostela Carlo Alberto RattiUniversità di Milano-Bicocca Marco RauchPhysikalisches Institut, Universität Bonn Ronald Reid-EdwardsUniversity of Hamburg Patricia RitterUniversity of Edinburgh Peter RoenneDESY, Hamburg Jan RosseelUniversità di Torino Clement RuefService de Physique Théorique, CEA Saclay Felix RustMax-Planck-Institut für Physik, München Thomas RyttovNiels Bohr Institute, København and CERN, Geneva Agustin Sabio VeraCERN, Geneva Christian SaemannTrinity College, Dublin Houman Safaai SISSA, Trieste Henning SamtlebenÉcole Normale Supérieure, Lyon Alberto SantambrogioIstituto Nazionale di Fisica Nucleare, Sezione di Milano Silviu Constantin SararuUniversity of Craiova Ricardo SchiappaCERN, Geneva Ionut Romeo SchiopuChalmers University, Göteborg Cornelius Schmidt-ColinetEidgenössische Technische Hochschule (ETH), Zürich Johannes SchmudeSwansea University Waldemar SchulginLaboratoire de Physique Théorique, École Normale Supérieure, Paris Domenico SeminaraUniversità di Firenze Alexander SevrinVrije Universiteit, Brussel Konstadinos SfetsosUniversity of Patras Igor ShenderovichSt Petersburg State University Jonathan ShockUniversidade de Santiago de Compostela Massimo SianiUniversità di Milano-Bicocca Christoph SiegUniversità Degli Studi di Milano Joan SimonUniversity of Edinburgh Paul SmythUniversity of Hamburg Luca SommovigoUniversidad de Valencia Dmitri Sorokin Istituto Nazionale di Fisica Nucleare, Padova Christos SourdisUniversity of Patras Wieland StaessensVrije Universiteit, Brussel Ivan StefanovUniversity of Patras Sigurdur StefanssonUniversity of Iceland Kellogg Stelle Imperial College London Giovanni Tagliabue Università di Milano Laura Tamassia Katholieke Universiteit Leuven Javier TarrioUniversidade de Santiago de Compostela Dimitri TerrynVrije Universiteit, Brussel Larus Thorlacius University of Iceland Mario ToninDipartimento Di Fisica, Sezione Di Padova Mario Trigiante Politecnico di Torino Efstratios TsatisUniversity of Patras Arkady TseytlinImperial College London Pantelis TziveloglouCornell University, New York and CERN, Geneva Angel Uranga CERN, Geneva Dieter Van den Bleeken Katholieke Universiteit Leuven Ernst van Eijk Università di Napoli Federico II Antoine Van Proeyen Katholieke Universiteit Leuven Maaike van ZalkUtrecht University Pierre Vanhove Service de Physique Théorique, CEA Saclay Silvia Vaula Instituto de Física Teórica, Universidad Autónoma de Madrid Cristian Vergu Service de Physique Théorique, CEA Saclay Alessandro VichiÉcole Polytechnique Fédérale de Lausanne (EPFL) Marlene WeissCERN, Geneva and Eidgenössische Technische Hochschule (ETH), Zürich Sebastian Weiss Université de Neuchâtel Alexander WijnsUniversity of Iceland Linus WulffUniversity of Padova Thomas WyderKatholieke Universiteit Leuven Ahmed YoussefAstroParticule et Cosmologie (APC), Université Paris Diderot Daniela ZanonUniversità Degli Studi di Milano Andrea ZanziPhysikalisches Institut, Universität Bonn Andrey ZayakinInstitute for Theoretical and Experimental Physics (ITEP), Moscow Tobias ZinggUniversity of Iceland Dimitrios ZoakosUniversidade de Santiago de Compostela Emanuele ZorzanUniversità di Milano Konstantinos ZoubosNiels Bohr Institute, København

The Law of Entropy Increase--A Lab Experiment

ERIC Educational Resources Information Center

Dittrich, William; Drosd, Robert; Minkin, Leonid; Shapovalov, Alexander S.

2016-01-01

The second law of thermodynamics has various formulations. There is the "Clausius formulation," which can be stated in a very intuitive way: "No process is possible whose sole result is the transfer of heat from a cooler to a hotter body." There is also the "Kelvin-Plank principle," which states that "no cyclic…

Eastern white pine secondary manufacturers: consumption, markets, and marketing

Treesearch

Delton Alderman; Robert Smith; Scott Bowe

2007-01-01

In the United States, eastern white pine (EWP) is used in the manufacture of interior planks, clapboards, furniture, doors and windows, decorative veneers, and moulding/millwork. Additional value-added markets for EWP raw material include toys, woodenware, novelties, signs, caskets, and products used in building construction (EWP furring was formerly a leading...

Judging and Actualizing Intrapersonal and Interpersonal Affordances

ERIC Educational Resources Information Center

Richardson, Michael J.; Marsh, Kerry L.; Baron, Reuben M.

2007-01-01

The current study investigated the perception of intrapersonal, interpersonal, and tool-based grasping possibilities. In Experiment 1, participants judged whether they would grasp planks of wood-presented in ascending, descending, and random orders of length-using one hand (1H), two hands (2H), or with a tool that extended their reach (TH). In…

Uncovered: Social Security, Retirement Uncertainty, and 1 Million Teachers

ERIC Educational Resources Information Center

Kan, Leslie; Aldeman, Chad

2014-01-01

Retirement savings are often described as a three-legged stool: Social Security, employer retirement plans, and personal savings. For many American workers, Social Security is the most consistent portion of the three-legged model, providing a solid plank of retirement savings. But nationwide, more than 1 million teachers--about 40 percent of all…

29 CFR 1926.858 - Removal of steel construction.

Code of Federal Regulations, 2011 CFR

2011-07-01

... of steel construction. (a) When floor arches have been removed, planking in accordance with § 1926.855(b) shall be provided for the workers engaged in razing the steel framing. (b) Cranes, derricks... 29 Labor 8 2011-07-01 2011-07-01 false Removal of steel construction. 1926.858 Section 1926.858...

29 CFR 1926.858 - Removal of steel construction.

Code of Federal Regulations, 2010 CFR

2010-07-01

... of steel construction. (a) When floor arches have been removed, planking in accordance with § 1926.855(b) shall be provided for the workers engaged in razing the steel framing. (b) Cranes, derricks... 29 Labor 8 2010-07-01 2010-07-01 false Removal of steel construction. 1926.858 Section 1926.858...

46 CFR 69.203 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., excluding rub rails, from the outboard side of the skin (outside planking or plating) on one side of the hull to the outboard side of the skin on the other side of the hull. Overall depth means the vertical distance taken at or near midships from a line drawn horizontally through the uppermost edges of the skin...

Indigenous Tutorial Assistance Scheme. Tertiary Tuition and Beyond: Transitioning with Strengths and Promoting Opportunities

ERIC Educational Resources Information Center

Wilks, Judith; Fleeton, Ellen Radnidge; Wilson, Katie

2017-01-01

The Indigenous Tutorial Assistance Scheme-Tertiary Tuition (ITAS-TT) has provided Australian government funding for one-to-one and group tutorial study support for Aboriginal and Torres Strait Islander students attending Australian universities since 1989. It has been a central plank supporting Indigenous university students in their studies.…

29 CFR 1926.858 - Removal of steel construction.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 8 2012-07-01 2012-07-01 false Removal of steel construction. 1926.858 Section 1926.858... of steel construction. (a) When floor arches have been removed, planking in accordance with § 1926.855(b) shall be provided for the workers engaged in razing the steel framing. (b) Cranes, derricks...

29 CFR 1926.858 - Removal of steel construction.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 8 2014-07-01 2014-07-01 false Removal of steel construction. 1926.858 Section 1926.858... of steel construction. (a) When floor arches have been removed, planking in accordance with § 1926.855(b) shall be provided for the workers engaged in razing the steel framing. (b) Cranes, derricks...

29 CFR 1926.858 - Removal of steel construction.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 8 2013-07-01 2013-07-01 false Removal of steel construction. 1926.858 Section 1926.858... of steel construction. (a) When floor arches have been removed, planking in accordance with § 1926.855(b) shall be provided for the workers engaged in razing the steel framing. (b) Cranes, derricks...

College Makes New Connections with Service-Learning Program

ERIC Educational Resources Information Center

Ashburn, Elyse

2009-01-01

The service learning movement has gained new energy with the election of President Obama, who has made increasing service a central plank of his higher-education agenda. But across the board, colleges and universities struggle with service learning's twin goals of providing meaningful help to the community and academic rigor to students. The…

A community-based aquatic exercise program to improve endurance and mobility in adults with mild to moderate intellectual disability.

PubMed

Hakim, Renée M; Ross, Michael D; Runco, Wendy; Kane, Michael T

2017-02-01

The purpose of this study was to investigate the impact of a community-based aquatic exercise program on physical performance among adults with mild to moderate intellectual disability (ID). Twenty-two community-dwelling adults with mild to moderate ID volunteered to participate in this study. Participants completed an 8-week aquatic exercise program (2 days/wk, 1 hr/session). Measures of physical performance, which were assessed prior to and following the completion of the aquatic exercise program, included the timed-up-and-go test, 6-min walk test, 30-sec chair stand test, 10-m timed walk test, hand grip strength, and the static plank test. When comparing participants' measures of physical performance prior to and following the 8-week aquatic exercise program, improvements were seen in all measures, but the change in scores for the 6-min walk test, 30-sec chair stand test, and the static plank test achieved statistical significance ( P <0.05). An 8-week group aquatic exercise program for adults with ID may promote improvements in endurance and balance/mobility.

Next-Generation Genetics in Plants: Evolutionary Trade-off, Immunity and Speciation (2010 JGI User Meeting)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiegel, Detlef

Detlef Wiegel from the Max Planck Institute for Developmental Biology on "Next-generation genetics in plants: Evolutionary tradeoffs, immunity and speciation" on March 25, 2010 at the 5th Annual DOE JGI User Meeting.

Next-Generation Genetics in Plants: Evolutionary Trade-off, Immunity and Speciation (2010 JGI User Meeting)

ScienceCinema

Wiegel, Detlef

2018-02-12

Detlef Wiegel from the Max Planck Institute for Developmental Biology on "Next-generation genetics in plants: Evolutionary tradeoffs, immunity and speciation" on March 25, 2010 at the 5th Annual DOE JGI User Meeting.

Use of 70 MeV Proton Beam for Medical Applications at INFN-LNS: CATANA Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sabini, M.G.; Cirrone, G.A.P.; Barone Tonghi, L.

The project CATANA (Centro di AdroTerapia ed Applicazioni Nucleari Avanzate) is a collaboration between the INFN-Laboratori Nazionali del Sud (LNS), Physics Department, Ophthalmology Institute and Radiology Institute of the Catania University and CSFNSM Catania. The main goal of CATANA is the study and the application of proton therapy for the treatment of shallow tumors (4 cm max) like uveal melanomas and subfoveal macular degenerations.

Use of 70 MeV proton beam for medical applications at INFN-LNS: CATANA project

NASA Astrophysics Data System (ADS)

Sabini, M. G.; Cirrone, G. A. P.; Tonghi, L. Barone; Bartolotta, A.; Brai, M.; Cuttone, G.; Nigro, S. Lo; Marano, F.; Nicoletti, G. A.; Privitera, G.; Raffaele, L.; Reibaldi, A.; Romeo, N.; Rovelli, A.; Salamone, V.; Teri, G.

2000-04-01

The project CATANA (Centro di Adro Terapia ed Applicazioni Nucleari Avanzate) is a collaboration between the INFN-Laboratori Nazionali del Sud (LNS), Physics Department, Ophthalmology Institute and Radiology Institute of the Catania University and CSFNSM Catania. The main goal of CATANA is the study and the application of protontherapy for the treatment of shallow tumors (4 cm max) like uveal melanomas and subfoveal macular degenerations.

Results from the Pan-STARRS1 Sky Surveys

NASA Astrophysics Data System (ADS)

Chambers, Kenneth C.; PS1 Science Consortium

2015-01-01

Results from the Pan-STARRS1 Sky Surveys spanning the field of astronomy from Near Earth Objects to Cosmology will be presented.Scientific highlights from the PS1 Sky Surveys include: the photometric and astrometric reference catalog with unprecedented size, accuracy, and dynamic range discovery of 1200 NEO's, 120 PHAs, 60 comets; discovery of rotational break up as the origin of catastrophic disruption of solar system bodies; first free floating planet PSO 318-22 and other ultra-cool objects; first 3-dimensional map of dust in the Milky Way; new distances to molecular clouds; new stellar streams in the Milky Way and new globular clusters; new satellite galaxies of M31; eclipsing binaries in M31 - an important step for the distance ladder; micro-lensing events and other variables in M31: super-luminous and under-luminous stellar explosions; first clear tidal disruption of star by supermassive black hole; many new high redshift quasars; and a new determination of the dark energy equation of state from SnIa photometry.The nearly 4 year Pan-STARRS1 Science Mission has now completed. The reprocessing of the entire data set is underway. The Public Release of the entire image, catalog and metadata set of the PS1 Sky Surveys is scheduled for April 1, 2015 from the STScI MAST archive. It is expected that a great many more scientific results will come with community access to the data set.The Pan-STARRS1 Surveys have been made possible through contributions of the Institute for Astronomy of the University of Hawaii; the Max-Planck Society and its participating institutes: the Max Planck Institute for Astronomy, Heidelberg and the Max Planck Institute for Extraterrestrial Physics, Garching; The Johns Hopkins University; Durham University; the University of Edinburgh; Queen's University Belfast; the Harvard-Smithsonian Center for Astrophysics, the Las Cumbres Observatory Global Telescope Network Incorporated; the National Central University of Taiwan; the Space Telescope Science Institute; NASA Grant No. NNX08AR22G; the National Science Foundation under Grant No. AST-1238877; the University of Maryland; the Eotvos Lorand University; and the Los Alamos National Laboratory.

Virtually-induced threat in Parkinson's: Dopaminergic interactions between anxiety and sensory-perceptual processing while walking.

PubMed

Ehgoetz Martens, Kaylena A; Ellard, Colin G; Almeida, Quincy J

2015-12-01

Research evidence has suggested that anxiety influences gait in PD, with an identified dopa-sensitive gait response in highly anxious PD. It has been well-established that accurate perception of the environment and sensory feedback is essential for gait. Arguably since sensory and perceptual deficits have been noted in PD, anxiety has the potential to exacerbate movement impairments, since one might expect that reducing resources needed to overcome or compensate for sensory-perceptual deficits may lead to even more severe gait impairments. It is possible that anxiety in threatening situations might consume more processing resources, limiting the ability to process information about the environment or one's own movement (sensory feedback) especially in highly anxious PD. Therefore, the current study aimed to (i) evaluate whether processing of threat-related aspects of the environment was influenced by anxiety, (ii) evaluate whether anxiety influences the ability to utilize sensory feedback in PD while walking in threatening situations, and (iii) further understand the role of dopaminergic medication on these processes in threatening situations in PD. Forty-eight participants (24 HC; 12 Low Anxious [LA-PD], 12 Highly Anxious [HA-PD]) completed 20 walking trials in virtual reality across a plank that was (i) located on the ground (GROUND) (ii) located above a deep pit (ELEVATED); while provided with or without visual feedback about their lower limbs (+VF; -VF). After walking across the plank, participants were asked to judge the width of the plank they had just walked across. The plank varied in size from 60-100 cm. Both ON and OFF dopaminergic medication states were evaluated in PD. Gait parameters, judgment error and self-reported anxiety levels were measured. Results showed that HA-PD reported greater levels of anxiety overall (p<0.001) compared to HC and LA-PD, and all participants reported greater anxiety during the ELEVATED condition compared to GROUND (p=0.01). PD had similar judgment error as HC. Additionally, medication state did not significantly influence judgment error in PD. More importantly, HA-PD were the only group that did not adjust their step width when feedback was provided during the GROUND condition. However, medication facilitated a reduction in ST-CV when visual feedback was available only in the HA-PD group. Therefore, the current study provides evidence that anxiety may interfere with information processing, especially utilizing sensory feedback while walking. Dopaminergic medication appears to improve utilization of sensory feedback in stressful situations by reducing anxiety and/or improving resource allocation especially in those with PD who are highly anxious. Copyright © 2015 Elsevier Ltd. All rights reserved.

Germany plans 60m euro physics and medicine lab

NASA Astrophysics Data System (ADS)

Stafford, Ned

2017-09-01

A new €60m medical-physics research lab is to be built in Erlangen, Germany, by the Max Planck Institute for the Science of Light (MPL) together with the Friedrich Alexander University Erlangen-Nürnberg and the University Hospital Erlangen.

Developing whole mycobacteria cell vaccines for tuberculosis: Workshop proceedings, Max Planck Institute for Infection Biology, Berlin, Germany, July 9, 2014.

PubMed

2015-06-12

On July 9, 2014, Aeras and the Max Planck Institute for Infection Biology convened a workshop entitled "Whole Mycobacteria Cell Vaccines for Tuberculosis" at the Max Planck Institute for Infection Biology on the grounds of the Charité Hospital in Berlin, Germany, close to the laboratory where, in 1882, Robert Koch first identified Mycobacterium tuberculosis (Mtb) as the pathogen responsible for tuberculosis (TB). The purpose of the meeting was to discuss progress in the development of TB vaccines based on whole mycobacteria cells. Live whole cell TB vaccines discussed at this meeting were derived from Mtb itself, from Bacille Calmette-Guérin (BCG), the only licensed vaccine against TB, which was genetically modified to reduce pathogenicity and increase immunogenicity, or from commensal non-tuberculous mycobacteria. Inactivated whole cell TB and non-tuberculous mycobacterial vaccines, intended as immunotherapy or as safer immunization alternatives for HIV+ individuals, also were discussed. Workshop participants agreed that TB vaccine development is significantly hampered by imperfect animal models, unknown immune correlates of protection and the absence of a human challenge model. Although a more effective TB vaccine is needed to replace or enhance the limited effectiveness of BCG in all age groups, members of the workshop concurred that an effective vaccine would have the greatest impact on TB control when administered to adolescents and adults, and that use of whole mycobacteria cells as TB vaccine candidates merits greater support, particularly given the limited understanding of the specific Mtb antigens necessary to generate an immune response capable of preventing Mtb infection and/or disease. Copyright © 2015. Published by Elsevier Ltd.. All rights reserved.

Fair Shares, Matey, or Walk the Plank

ERIC Educational Resources Information Center

Wilson, P. Holt; Myers, Marrielle; Edgington, Cyndi; Confrey, Jere

2012-01-01

Whether sharing a collection of toys among friends or a pie for dessert, children as young as kindergarten age are keen on making sure that everyone gets their "fair share." In the classroom, fair-sharing activities call for creating equal-size groups from a collection of objects or creating equal-size parts of a whole and are generally used by…

23. VIEW TOWARD EAST CORNER OF ROOM 205. FORMER SKYLIGHT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. VIEW TOWARD EAST CORNER OF ROOM 205. FORMER SKYLIGHT IN SLOPED GYPSUM BOARD CEILING HAS BEEN ROOFED OVER. WALLS ARE A COMBINATION OF GYPSUM BOARD AND WOOD PLANK. WOOD POST SUPPORTS BEAM AT NORTHEAST WALL. - Presidio of San Francisco, Cavalry Stables, Cowles Street, between Lincoln Boulevard & McDowell Street, San Francisco, San Francisco County, CA

IDEF5 Ontology Description Capture Method: Concepts and Formal Foundations

DTIC Science & Technology

1992-11-01

cutter comes to exist. The puzzle here goes back to Greek times iii the guise of the Ship of Theseus : if we bit by bit replace the planks of a ship...831 Barwise, J. and Perry, J., Situations and Attitudes, The MIT Press, Cambridge, 1983. [Burch 911 Burch, R., A Peircean Reduction Thesis : The

Same Name as Father: Is Being a Junior a Help or a Handicap?

ERIC Educational Resources Information Center

Yao, Blake

The relationship between mental illness and the practice of naming a son after the father was investigated. Plank and Cameron suggested that individuals who carry their father's name often live under the father's shadow, and this might influence the social/emotional development of the individual. Previous reports of rates of mental illness among…

The Universe Adventure - The Plank Epoch

Science.gov Websites

Physics In the time before the first 10-44 seconds of the Universe, or the Planck Epoch, the laws of physics as we know them break down; the predictions of General Relativity become meaningless as distance physics models predict that during this epoch the four fundamental forces were combined into one unified

84. Photocopied August 1978. REPAIRING FOREBAY LEAK, NOVEMBER 1907. THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

84. Photocopied August 1978. REPAIRING FOREBAY LEAK, NOVEMBER 1907. THE PILE-DRIVER IS DRIVING NEW PILES FOR THE FOREBAY APRON, CLAY BACKFILL AND PLANKING CREWS ARE BUSY AT THE RIGHT. MUCH OF THE FOREBAY FLOOR WAS ALSO REPLANKED AT THIS TIME. (520) - Michigan Lake Superior Power Company, Portage Street, Sault Ste. Marie, Chippewa County, MI

4D Sommerfeld quantization of the complex extended charge

NASA Astrophysics Data System (ADS)

Bulyzhenkov, Igor E.

2017-12-01

Gravitational fields and accelerations cannot change quantized magnetic flux in closed line contours due to flat 3D section of curved 4D space-time-matter. The relativistic Bohr-Sommerfeld quantization of the imaginary charge reveals an electric analog of the Compton length, which can introduce quantitatively the fine structure constant and the Plank length.

15. Photocopy of photograph (original 43/4 x 33/4 inch print ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. Photocopy of photograph (original 4-3/4 x 3-3/4 inch print located in the Recreation files, Mt. Baker-Snoqualmie N. F.). Photographer unknown, ca. 1941 SKI WARMING HUT, AUSTIN PASS, GLACIER DISTRICT. (NOTE PLANK SPANNING GAP BETWEEN KNOLL AND PORCH) - Austin Pass Warming Hut, Washington Highway 542, Glacier, Whatcom County, WA

The Social Outcomes of Learning Mathematics: Standard, Unintended or Visionary?

ERIC Educational Resources Information Center

Ernest, Paul

2015-01-01

Mathematics is a fundamental part of human knowledge and one of the central planks of the modern technological revolution. But in our enthusiasm to promote its benefits too rarely do we stop to question our intended aims of teaching mathematics and the outcomes of learning mathematics in school. In this paper the standard aims of school…

Mini MAX-DOAS Measurements of Air Pollutants over China

NASA Astrophysics Data System (ADS)

Staadt, Steffen; Hao, Nan; Trautmann, Thomas

2016-08-01

This study continues the work of Clémer et al., (2010) and is aimed to improve trace gas retrievals with mini MAX-DOAS measurements in Nanjing. Based on that work, aerosol extinction vertical profiles are retrieved using the bePRO inversion algorithm developed by the Royal Belgian Institute for Space Aeronomy (BIRA- IASB). Afterwards, the tropospheric trace gas vertical profiles and vertical column densities (VCDs) are retrieved by applying the optimal estimation method to the O4 MAX-DOAS measurements. The Profiles for N O2 , S O2 , glyoxal, formaldehyde and nitrous acid are obtained with different results and different settings for the DOAS measurement. The AODs show small positive correlation against the AERONET values. For NO2, the retrieval shows reasonable concentrations in winter as opposed to summer and has small positive correlations with GOME-2 data. The SO2 VCDs are not correlated with the GOME-2 data, due to high uncertainties from MAX-DOAS and satellite retrievals, while the vertical mixing ratios (VMR) show good agreement with in-situ data (SORPES) at Nanjing. Nitrous acid shows a maximum in winter and a minimum in summer, while glyoxal has its maximum in August and September.

Design Issues Related to the Evaluation of Learner--Computer Interaction in a Web-Based Environment: Activities v. Tasks

ERIC Educational Resources Information Center

Hemard, Dominique

2006-01-01

If web-based technology is increasingly becoming the central plank of contemporary teaching and learning processes, there is still too little evidence to suggest that it is delivering purposeful learning activities beyond its widely perceived potential as a learning resource providing content and learning objects. This is due in part to the…

8. VIEW LOOKING NORTHWEST DOWN CENTRAL AXIS OF ROOM 110. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. VIEW LOOKING NORTHWEST DOWN CENTRAL AXIS OF ROOM 110. NOTE CHANGE IN CEILING TREATMENT: WOOD PLANKS IN CENTER, ALL OTHER AREAS ARE GYPSUM BOARD. FLOOR IN CENTRAL AREA IS CONCRETE. POSTS AND BEAMS ARE ALL WOOD CONSTRUCTION. - Presidio of San Francisco, Cavalry Stables, Cowles Street, between Lincoln Boulevard & McDowell Street, San Francisco, San Francisco County, CA

A Training Program for the 1990s: Reflecting on Campaign Proposals. Occasional Paper 1992-4.

ERIC Educational Resources Information Center

Levitan, Sar A.; And Others

National concern about U.S. competitiveness in the world market has focused attention on the need to improve the work force. The two major 1992 presidential candidates have included training programs as important planks in their campaigns. President Bush has issued two proposals. Initially, he has charged in the Job Training 2000 proposal that the…

Estimating bridge stiffness using a forced-vibration technique for timber bridge health monitoring

Treesearch

James P. Wacker; Xiping Wang; Brian Brashaw; Robert J. Ross

2006-01-01

This paper describes an effort to refine a global dynamic testing technique for evaluating the overall stiffness of timber bridge superstructures. A forced vibration method was used to measure the frequency response of several simple-span, sawn timber beam (with plank deck) bridges located in St. Louis County, Minnesota. Static load deflections were also measured to...

Novel Combinatorial Immunotherapy for Melanoma

DTIC Science & Technology

2015-10-01

table discussions regarding career development. 5. The department of Microbiology & Molecular Genetics hosts once a month seminar series regarding...ORGANIZATION: Medical college of Wisconsin Hanover, NH 03755 REPORT DATE: Oct 2015 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical ...NAME(S) AND ADDRESS(ES) Medical College of Wisconsin Inc, 8701 Watertown Plank Rd. n 8. PERFORMING ORGANIZATION REPORT NUMBER Milwaukee, WI 53226

Sausage Rolls and Sports Fields: The Debate over Voluntary Student Unionism in Australia

ERIC Educational Resources Information Center

Rochford, Francine

2006-01-01

The Australian Federal Government recently amended the Higher Education Support Act 2003. The effect of this amendment, which came into force on 1 January 2006, is to abolish compulsory up-front fees for the funding of student unions. Voluntary student unionism has been a plank of the Liberal (conservative) platform for many years, but its…

Footwear effects on walking balance at elevation.

PubMed

Simeonov, Peter; Hsiao, Hongwei; Powers, John; Ammons, Douglas; Amendola, Alfred; Kau, Tsui-Ying; Cantis, Douglas

2008-12-01

The study evaluated the effects of shoe style on workers' instability during walking at elevation. Twenty-four construction workers performed walking tasks on roof planks in a surround-screen virtual reality system, which simulated a residential roof environment. Three common athletic and three work shoe styles were tested on wide, narrow and tilted planks on a simulated roof and on an unrestricted surface at simulated ground. Dependent variables included lateral angular velocities of the trunk and the rear foot, as well as the workers' rated perceptions of instability. The results demonstrated that shoe style significantly affected workers walking instability at elevated work environments. The results highlighted two major shoe-design pathways for improving walking balance at elevation: enhancing rear foot motion control; and improving ankle proprioception. This study also outlined some of the challenges in optimal shoe selection and specific shoe-design needs for improved walking stability during roof work. The study adds to the knowledge in the area of balance control, by emphasising the role of footwear as a critical human-support surface interface during work on narrow surfaces at height. The results can be used for footwear selection and improvements to reduce risk of falls from elevation.

Weak meson decays and the 1/Nc expansion

NASA Astrophysics Data System (ADS)

Tadić, Dubravko; Trampetić, Josip

1982-07-01

In the QCD corrected weak hamiltonian, the leading terms in the large-Nc limit give a reasonable description of D--> Kπ decays and good values of K --> ππ decay amplitudes. Alexander von Humboldt Fellow of Max-Planck Institut für Physik und Astrophysik, Munich, Fed. Rep. Germany.

Comparing exercise responses to aerobic plus resistance training between postmenopausal breast cancer survivors undergoing aromatase inhibitor therapy and healthy women.

PubMed

Paulo, Thais R S de; Winters-Stone, Kerri M; Viezel, Juliana; Rossi, Fabricio E; Aro, Bruna L; Trindade, Ana Carolina A C; Codogno, Jamile S; Freitas Junior, Ismael F

2018-04-12

The aim of this study was to explore whether postmenopausal breast cancer survivors undergoing aromatase inhibitor therapy differ from healthy postmenopausal women in their response to the same aerobic + resistance training. The participants were separated into two groups: postmenopausal breast cancer survivors undergoing aromatase inhibitor therapy for an average of 20 months (18 women) and healthy postmenopausal women (24 women). We assessed aerobic capacity (predicted maximum oxygen uptake (VO 2 max) and maximum running velocity test (Vmax)) through a walking test, upper and lower body muscle strength using an estimated one-repetition maximum test, and body composition by dual-energy X-ray absorptiometry at baseline and at three, six, and nine months, respectively. The exercise program was performed three times/week over nine months and consisted of 40 min of machine-based strength training (seated cable row, bench press, leg extension, leg press, and leg curl, as well as bridge, abdominal, and standard plank exercises) followed by 30 min of treadmill walking. Analysis of variance (ANOVA) with repeated measures was used to compare the groups over time. Postmenopausal breast cancer survivors undergoing aromatase inhibitor therapy and healthy postmenopausal women presented similar improvements in estimated lower body strength, predicted VO 2max and V max , and body fat mass. For maximal upper body strength, there was a significant group x time interaction after six months of training (p = 0.01). The healthy postmenopausal women presented a significant increase in upper body strength after six months, while postmenopausal breast cancer survivors undergoing aromatase inhibitor therapy demonstrated an improvement only at nine months of training. The breast cancer survivors undergoing aromatase inhibitor therapy presented increased lean mass while healthy postmenopausal women maintained values over time (Breast cancer: 33.7 ± 3.9(Pre) vs. 34.1 ± 3.4 kg (Post) and healthy women: 36.4 ± 5.1 (Pre) vs. 36.4 ± 5.0 kg (Post), p = 0.004). Our findings suggest that postmenopausal women undergoing aromatase inhibitor therapy for breast cancer demonstrated adaptations and similar trainability to the same regimen of resistance + aerobic training as healthy postmenopausal women. Implications for Rehabilitation Combined exercise program (aerobic plus resistance) is an important non-pharmacological strategies to improve strength, aerobic capacity, and body composition in breast cancer survivors undergoing aromatase inhibitor therapy. Furthermore, it is important to highlight that the time of intervention seems to influence the upper body strength response in this population. This study showed that trainers and other specialists do not need to modify the prescription of exercise related to healthy women, since the combined exercise program induced similar benefits in strength, aerobic capacity, and body composition in postmenopausal breast cancer survivors undergoing aromatase inhibitor therapy and healthy postmenopausal women.

Trends in leaf photosynthesis in historical rice varieties developed in the Philippines since 1966.

PubMed

Hubbart, S; Peng, S; Horton, P; Chen, Y; Murchie, E H

2007-01-01

Crop improvement in terms of yield is rarely linked to leaf photosynthesis. However, in certain crop plants such as rice, it is predicted that an increase in photosynthetic rate will be required to support future grain yield potential. In order to understand the relationships between yield improvement and leaf photosynthesis, controlled environment conditions were used to grow 10 varieties which were released from the International Rice Research Institute (IRRI) between 1966 and 1995 and one newly developed line. Two growth light intensities were used: high light (1500 micromol m(-2) s(-1)) and low light (300 micromol m(-2) s(-1)). Gas exchange, leaf protein, chlorophyll, and leaf morphology were measured in the ninth leaf on the main stem. A high level of variation was observed among high light-grown plants for light-saturated photosynthetic rate per unit leaf area (P(max)), stomatal conductance (g), content of ribulose bisphosphate carboxylase-oxygenase (Rubisco), and total leaf protein content. Notably, between 1966 and 1980 there was a decline in P(max), g, leaf protein, chlorophyll, and Rubisco content. Values recovered in those varieties released after 1980. This striking trend coincides with a previous published observation that grain yield in IRRI varieties released prior to 1980 correlated with harvest index whereas that for those released after 1980 correlated with biomass. P(max) showed significant correlations with both g and Rubisco content. Large differences were observed between high light- and low light-grown plants (photoacclimation). The photoacclimation 'range' for P(max) correlated with P(max) in high light-grown plants. It is concluded that (i) leaf photosynthesis may be systematically affected by breeding strategy; (ii) P(max) is a useful target for yield improvements where yield is limited by biomass production rather than partitioning; and (iii) the capacity for photoacclimation is related to high P(max) values.

Impacts of peatland forestation on regional climate conditions in Finland

NASA Astrophysics Data System (ADS)

Gao, Yao; Markkanen, Tiina; Backman, Leif; Henttonen, Helena M.; Pietikäinen, Joni-Pekka; Laaksonen, Ari

2014-05-01

Climate response to anthropogenic land cover change happens more locally and occurs on a shorter time scale than the global warming due to increased GHGs. Over the second half of last Century, peatlands were vastly drained in Finland to stimulate forest growth for timber production. In this study, we investigate the biophysical effects of peatland forestation on near-surface climate conditions in Finland. For this, the regional climate model REMO, developed in Max Plank Institute (currently in Climate Service Center, Germany), provides an effective way. Two sets of 15-year climate simulations were done by REMO, using the historic (1920s; The 1st Finnish National Forest Inventory) and present-day (2000s; the 10th Finnish National Forest Inventory) land cover maps, respectively. The simulated surface air temperature and precipitation were then analyzed. In the most intensive peatland forestation area in Finland, the differences in monthly averaged daily mean surface air temperature show a warming effect around 0.2 to 0.3 K in February and March and reach to 0.5 K in April, whereas a slight cooling effect, less than 0.2 K, is found from May till October. Consequently, the selected snow clearance dates in model gridboxes over that area are advanced 0.5 to 4 days in the mean of 15 years. The monthly averaged precipitation only shows small differences, less than 10 mm/month, in a varied pattern in Finland from April to September. Furthermore, a more detailed analysis was conducted on the peatland forestation area with a 23% decrease in peatland and a 15% increase in forest types. 11 day running means of simulated temperature and energy balance terms, as well as snow depth were averaged over 15 years. Results show a positive feedback induced by peatland forestation between the surface air temperature and snow depth in snow melting period. This is because the warmer temperature caused by lower surface albedo due to more forest in snow cover period leads to a quicker and earlier snow melting. Meanwhile, surface albedo is reduced and consequently surface air temperature is increased. Additionally, the maximum difference from individual gridboxes in this area over 15 years of 11 day running means of daily mean surface air temperature reaches 2 K, which is four times as much as the maximum difference of 15-year regional average of that. This illustrates that the spring warming effect from peatland forestation in Finland is highly heterogeneous spatially and temporally.

Using What We Know: A Review of the Research on Implementing Class-Size Reduction Initiatives for State and Local Policymakers.

ERIC Educational Resources Information Center

Laine, Sabrina W. M., Ed.; Ward, James G., Ed.

This book contains a collection of essays involving new research on class-size reduction. Six chapters include: (1) "Reducing Class Size in Public Schools: Cost-Benefit Issues and Implications" (John F. Witte); (2) "Making Policy Choices: Is Class-Size Reduction the Best Alternative?" (Doug Harris and David N. Plank); (3) "Smaller Classes, Lower…

105. VIEW NORTH FROM SLC3W CABLE TUNNEL INTO CABLE VAULT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

105. VIEW NORTH FROM SLC-3W CABLE TUNNEL INTO CABLE VAULT AND SLC-3E CABLE TUNNEL. NOTE WOODEN PLANKING ON FLOOR OF TUNNEL AND CABLE TRAYS LINING TUNNEL WALLS. STAIRS ON EAST WALL OF CABLE VAULT LEAD INTO LANDLINE INSTRUMENTATION ROOM. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Operations Building, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

Hammam Al Alil Division Training Center Mosul, Iraq

DTIC Science & Technology

2010-01-07

displacement of the concrete slab. The SOW required translucent material for the cladding and provided specific details for windows inserted in the...of poor curing practice; however, SIGIR did not observe any significant cracking or displacement of the concrete slab. The SOW required translucent ...Documentation that addressed the safety concerns of removing the overhead baffles was not available. In addition, the contractor used precast concrete planks

10. INTERIOR VIEW OF ROOM 110, LOOKING NORTHWEST FROM THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. INTERIOR VIEW OF ROOM 110, LOOKING NORTHWEST FROM THE EAST CORNER. SPACE IS DIVIDED BY EXPOSED POSTS AND BEAMS DESIGNATING ANIMALS QUARTERS AND AISLES. FLOORS ARE WOOD PLANKS IN ANIMAL AREAS CHANGING TO CONCRETE IN CENTER AISLES. CEILING IS GYPSUM BOARD. - Presidio of San Francisco, Cavalry Stables, Cowles Street, between Lincoln Boulevard & McDowell Street, San Francisco, San Francisco County, CA

Information Metering: Paving the Way for Pay-per-View Information.

ERIC Educational Resources Information Center

Hawkins, Donald T.

1996-01-01

Describes information metering technology as a method that information providers use to provide information collections to users in encrypted form and charge them only for the parts actually used. Discusses how two current information metering systems (Wave Systems Corporation and CD-MAX) operate, the institutions using their systems, and the…

Towards an Understanding of Power Relationships in Institutional Abuse.

ERIC Educational Resources Information Center

Jones, Jocelyn

1994-01-01

Uses Max Weber's ideas of domination to analyze the authority structure in an English private boy's school where physical and sexual abuse were perpetrated by the school's principal and owner. Discusses how domination was constructed and maintained, how victims were selected, and how relations outside the school were managed. Suggests current…

Globalizing Globalization: The Neo-Institutional Concept of a World Culture

ERIC Educational Resources Information Center

Trohler, Daniel

2009-01-01

In this paper, the author focuses on how globalization and education are addressed in research. More precisely, he concentrates on only one dominant approach to analyzing globalization and its effects on education and also the educational role within globalization. His thesis is that, with the background of Max Weber's Protestant ethic thesis,…

The virtual laboratory: a new on-line resource for the history of psychology.

PubMed

Schmidgen, Henning; Evans, Rand B

2003-05-01

The authors provide a description of the Virtual Laboratory at Department III of the Max Planck Institute for the History of Science in Berlin. The Virtual Laboratory currently provides Internet links to rooms that present texts, instruments, model organisms, research sites, and biographies. Existing links provide access to a library of journals, handbooks, monographs, and trade catalogues; research institutes and laboratories; biographies and bibliographic essays; and essays by contemporary researchers. Historians of psychology are encouraged to submit photographic material and essays to the Virtual Laboratory.

Proton-hydrogen collisions for Rydberg n,l-changing transitions in the early Universe

NASA Astrophysics Data System (ADS)

Vrinceanu, Daniel

2013-05-01

Cosmic Microwave Background (CMB) is a vestige radiation generated during the Recombination era, some 390,000 years after the Big Bang, when the Universe had become transparent for the first time. Initial observations of CMB made by the Wilkinson Microwave Anisotropy Probe (WMAP) led to determining the age of the Universe. The mechanisms that drove the recombination have been discovered by using modeling of the primordial plasma and seeking agreement with the observations. The new Plank Surveyor Instrument launched in 2009 is expected to produce data about the recombination era of an unprecedented accuracy, that require including better information regarding the basic atomic physics processes into the present models. In this talk, I will review the results for various Rydberg atom - charge particle collisions and establish their relative importance during the stages of recombination era, with respect to each other and to radiative processes. Energy changing and angular momentum changing collisions with electrons and ions are considered. This work has been supported by NSF through grants to the Institute for Theoretical Atomic and Molecular Physics at Harvard Smithsonian Center for Astrophysics and to the Center for Research on Complex Networks at Texas Southern University.

Oral History Interview Transcripts Tombigbee Historic Townsites Project. Volume 4 (Interview Numbers 117-122).

DTIC Science & Technology

1981-01-01

Creek. They had one family of Hamptons and one family of Bananas . Bull Banana’s widow lives over here about a mile from me. I believe that the Ellises... peeled . I don’t know whether she peeled apples or not, but she would peel the peaches. Spread them out in the sunshine on a plank or a piece of tin

Air Force Civil Engineer, Volume 15, Number 3, 2007

DTIC Science & Technology

2007-01-01

Korea during the winter. The runway is made of pierced steel plank . (U.S. Air Force photo) Transforming Air Force Firefighting...expect the fire chief and fire marshal to inform installation leadership when the mission is potentially impacted and to advocate risk mitigation...measures, and we expect leadership to listen. The use of “manage” in the phrase indicates that FES flights are expected to manage the event to the

An Advanced Tabu Search Approach to Solving the Mixed Payload Airlift Load Planning Problem

DTIC Science & Technology

2009-03-01

cargo, and the problem therefore becomes trivial. 3. Shoring: Some cargo requires shoring which is small planks of plywood stacked on top of each...Integer Programming Method In 1989, Kevin Ng examined the bin-packing MPALP for Canada’s C-130 aircraft (Ng 1992). His goal was to move a set of... leadership & ethics [ ] warfighting [ ] international security [ ] doctrine [X] other (specify): Military Airlift

2. EXTERIOR OF FRONT (EAST SIDE) OF BUILDING 105 SHOWING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. EXTERIOR OF FRONT (EAST SIDE) OF BUILDING 105 SHOWING RECESSED PORCH FRAMED BY CRISS-CROSS WOOD BALUSTRADE, STONE FACING ALONG ORIGINAL PORTION OF HOUSE FRONT, AND ORIGINAL PLANK DOOR TO PORCH BASEMENT AT LOWER PHOTO CENTER. WELDED STEEL PORCH RAILINGS VISIBLE AT PHOTO LEFT CENTER WERE ADDED IN 1972. VIEW TO NORTHWEST. - Rush Creek Hydroelectric System, Worker Cottage, Rush Creek, June Lake, Mono County, CA

Planet of the apes.

PubMed

Maderspacher, Florian

2005-03-08

What makes us humans so special? Our language, our genes, our culture, our cognitive skills? At the Max-Planck-Institute for Evolutionary Anthropology in Leipzig, psychologists, linguists and biologists tackle this old question in a truly multidisciplinary way. Their results have implications not just for our understanding of human evolution--they also touch directly on many social and environmental issues. Florian Maderspacher reports.

The Freedoms and Limits of Tenure: An Ideal Typology of Educational Researchers.

ERIC Educational Resources Information Center

McClafferty, Karen Ann

A study was conducted to explore the factors that have impact on the individual freedom and autonomy of academics in the changing university climate. Through the development of an ideal typology of educational researchers, based on the work of Max Weber, the study reveals the ways in which individuals within these changing institutions make…

Photovoltaic Prospection in South Tamaulipas

NASA Astrophysics Data System (ADS)

Saleme Vila, S.; Rivas, D.; Ortega Izaguirre, R.

2015-12-01

Commercial monocrystalline silicon (c-Si), polycrystalline silicon (p-Si) and amorphous silicon (a-Si) photovoltaic (PV) panels are tested on real conditions in order to identify which of the aforementioned PV panels present the best performance in the city of Altamira, Tamaulipas (northeastern Mexico) and to evaluate the impact of the city's climatic conditions over the electrical characteristics and power generation of the aforementioned PV panels. In situ direct solar irradiance and current-voltage characteristics (I-V) of each PV panel were taken from Monday to Friday at 11:00, 13:00 and 15:00 hours (GMT-6) with 3 repeats from 08/04/2014 to 07/31/2015. Also, daylong in situ direct solar irradiance, panel temperature, and I-V characteristics were taken from 8:00 to 20:30 hours with a 30-minute interval in synchrony with National Polytechnic Institute-owned CICATA-I meteorological station in order to cross-reference the experimental data with the station's air temperature, specific humidity and global solar irradiance data. Up to June 2015, c-Si panel presented the best performance on real conditions with mean max power loss of 49% compared to the reference max power value followed by the p-Si with 54% mean max power loss and the a-Si panel with a 73% mean max power loss. The number of cloudy days, electrical resistance due to panel materials nature and meteorological impact are further discussed.

Pretreatment [{sup 18}F]-fluoro-2-deoxy-glucose Positron Emission Tomography Maximum Standardized Uptake Value as Predictor of Distant Metastasis in Early-Stage Non-Small Cell Lung Cancer Treated With Definitive Radiation Therapy: Rethinking the Role of Positron Emission Tomography in Personalizing Treatment Based on Risk Status

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nair, Vimoj J.; MacRae, Robert; Ottawa Hospital Research Institute, Ottawa, Ontario

2014-02-01

Purpose: The aim of this study was to determine whether the preradiation maximum standardized uptake value (SUV{sub max}) of the primary tumor for [{sup 18}F]-fluoro-2-deoxy-glucose positron emission tomography (FDG-PET) has a prognostic significance in patients with Stage T1 or T2N0 non-small cell lung cancer (NSCLC) treated with curative radiation therapy, whether conventional or stereotactic body radiation therapy (SBRT). Methods and Materials: Between January 2007 and December 2011, a total of 163 patients (180 tumors) with medically inoperable histologically proven Stage T1 or T2N0 NSCLC and treated with radiation therapy (both conventional and SBRT) were entered in a research ethics boardmore » approved database. All patients received pretreatment FDG-PET / computed tomography (CT) at 1 institution with consistent acquisition technique. The medical records and radiologic images of these patients were analyzed. Results: The overall survival at 2 years and 3 years for the whole group was 76% and 67%, respectively. The mean and median SUV{sub max} were 8.1 and 7, respectively. Progression-free survival at 2 years with SUV{sub max} <7 was better than that of the patients with tumor SUV{sub max} ≥7 (67% vs 51%; P=.0096). Tumors with SUV{sub max} ≥7 were associated with a worse regional recurrence-free survival and distant metastasis-free survival. In the multivariate analysis, SUV{sub max} ≥7 was an independent prognostic factor for distant metastasis-free survival. Conclusion: In early-stage NSCLC managed with radiation alone, patients with SUV{sub max} ≥7 on FDG-PET / CT scan have poorer outcomes and high risk of progression, possibly because of aggressive biology. There is a potential role for adjuvant therapies for these high-risk patients with intent to improve outcomes.« less

Aeronautical Mobile Airport Communications System (AeroMACS)

NASA Technical Reports Server (NTRS)

Budinger, James M.; Hall, Edward

2011-01-01

To help increase the capacity and efficiency of the nation s airports, a secure wideband wireless communications system is proposed for use on the airport surface. This paper provides an overview of the research and development process for the Aeronautical Mobile Airport Communications System (AeroMACS). AeroMACS is based on a specific commercial profile of the Institute of Electrical and Electronics Engineers (IEEE) 802.16 standard known as Wireless Worldwide Interoperability for Microwave Access or WiMAX (WiMax Forum). The paper includes background on the need for global interoperability in air/ground data communications, describes potential AeroMACS applications, addresses allocated frequency spectrum constraints, summarizes the international standardization process, and provides findings and recommendations from the world s first AeroMACS prototype implemented in Cleveland, Ohio, USA.

[The history of the Kaiser Wilhelm Society during the Third Reich. Interim reports of the president's commission of the Max Planck Society].

PubMed

Weber, M M

2002-11-01

In 1997 the Max Planck Society set up a presidential commission to do research on the historical development of its precursor organization, the Kaiser Wilhelm Society (KWG), during the Third Reich. This paper presents some of the important results given in the interim reports of this commission that are relevant to psychiatry. It focuses on brain research, anthropology, psychiatric genetics, and the role of the well-known biochemist Adolf Butenandt. In general, the interim reports reflect the numerous links between the biomedical research of the KWG and the institutions of the National Socialist (Nazi) state. However, they do not yet allow a final historical assessment as to the complex situation of this field of research during National Socialism.

8. View southwest at the northeastern end of culvert inlet, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. View southwest at the northeastern end of culvert inlet, with canal bank completely removed. Left to right: back of curved wingwall; tops of high inlet barrels; vertical transition wall between high inlet barrels and low interior barrels; tops of low, interior barrels; vertical heartening planks at former canal edge of canal bank. - Delaware & Raritan Canal, Ten Mile Run Culvert, 1.5 miles South of Blackwells Road, East Millstone, Somerset County, NJ

6. View southwest, culvert inlet with canal bank completely removed. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. View southwest, culvert inlet with canal bank completely removed. Left to right: back of headwall; tops of high inlet barrels; vertical transition wall between high inlet barrels and low, interior, inlet barrels; tops of low interior barrels; vertical heartening planks and low cutoff wall along former edge of canal bank; dewatered canal bed. - Delaware & Raritan Canal, Ten Mile Run Culvert, 1.5 miles South of Blackwells Road, East Millstone, Somerset County, NJ

The Holloman Test Track Impact Area Archeological Survey

DTIC Science & Technology

1988-07-25

must be addressed 23 HOLLOMAN TEST TRACK IMPACT AREA SURVEY before data from the basin floor can contribute (5) What lnds of excavation contexts ar ...and chronology can be determined or Based on these considerations, the following questions are suggested, how might survey sites be used to designed to...scatter of artifact assemblages are listed in Appendix 4. wood planks, cans , and broken glass. The glass assemblage is limited but includes a Clorox

Benefit from NASA

NASA Image and Video Library

1995-01-01

In this photograph, James Carden uses a NASA-developed prosthesis to moved planks around his home. Derived from foam insulation technology used to protect the Space Shuttle External Tank from excessive heat, FAB/CAD, a subsidiary of the Harshberger Prosthetic and Orthotic Center, utilized the technology to replace the heavy, fragile plaster they used to produce master molds for prosthetics. The new material was lighter, cheaper and easier to manufacture than plaster, resulting in lower costs to the customer.

Implications of the Military Reform Movement for the Army’s PPBES.

DTIC Science & Technology

1986-05-15

outnumbered and outgunned. Consequently we should employ a Jacksonian/Wehrnacht style of maneuver warfare. This warfare emphasizes the use of grand scale...World Affairs, Volume 27, Number 2, Summer 1983, p. 247. Note that the particulars under the three groups were abstracted by me. 2. Kevin N. Lewis...to assure coordination. The classical solution for this problem is "gang planking ", i.e., coordination is assured because of horizontal relationships

A Guide to Scaffold Use in the Construction Industry

DTIC Science & Technology

2001-01-01

1926.451(e)(5)) and •integral prefabricated frames. (1926.451(e)(6)) What are the access requirements for employees erecting and dismantling supported...guardrails which block employee access to the cantilevered end. (6) On scaffolds where scaffold planks are abutted to create a long platform, each... abutted end shall rest on a separate support surface. This provision does not preclude the use of common support members, such as “T” sections, to support

Prosthesis Material

NASA Technical Reports Server (NTRS)

1995-01-01

In this photograph, James Carden uses a NASA-developed prosthesis to moved planks around his home. Derived from foam insulation technology used to protect the Space Shuttle External Tank from excessive heat, FAB/CAD, a subsidiary of the Harshberger Prosthetic and Orthotic Center, utilized the technology to replace the heavy, fragile plaster they used to produce master molds for prosthetics. The new material was lighter, cheaper and easier to manufacture than plaster, resulting in lower costs to the customer.

Molecules at surfaces: 100 years of physical chemistry in Berlin-Dahlem.

PubMed

Ertl, Gerhard

2013-01-02

Scratching the surface: for over 100 years the interactions of molecules at surfaces have been studied at the Fritz Haber Institute of the Max Planck Society, Berlin. Nobel Laureate Gerhard Ertl looks back at some of the key developments in this time, and the people who made them. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

AGARD Manual on Aeroelasticity in Axial-Flow Turbomachines. Volume 1. Unsteady Turbomachinery Aerodynamics

DTIC Science & Technology

1987-03-01

highly specialized unsteady aerodynamic and aeroelastic information to the turbomachinery design community and the introduction of young engineers to this...dynamics and aeroelas- ticity will be found useful as an introduction to this important special discipline and as a basis for future work. Max F...I. INTRODUCTION AND OVERVIEW F.Sisto, Stevens Institute of Technology Introduction

Imaging the Oxygen-Rich Disk Toward the Silicate Carbon Star EU Andromedae

DTIC Science & Technology

2007-12-01

star EU Andromedae K. Ohnaka1 and D. A. Boboltz2 1 Max-Planck-Institut für Radioastronomie, Auf dem Hügel 69, 53121 Bonn, Germany e-mail: kohnaka...Imaging the Oxygen-Rich Disk Toward the Silicate Carbon Star EU Andromedae 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR

12 CFR 217.145 - Recognition of credit risk mitigants for securitization exposures.

Code of Federal Regulations, 2014 CFR

2014-01-01

... recognize the credit risk mitigant, but only as provided in this section. (b) Collateral. (1) Rules of...*) to original exposure amount (SE), Where: (i) SE* = max {0, [SE−C × (1−Hs−Hfx)]}; (ii) SE = the amount... type haircuts (Hs) in Table 1 to § 217.132 of this subpart; (ii) A Board-regulated institution must use...

77 FR 14504 - Max Planck Florida Institute, et al.; Notice of Consolidated Decision on Applications for Duty...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-12

... decision consolidated pursuant to Section 6(c) of the Educational, Scientific, and Cultural Materials... records can be viewed between 8:30 a.m. and 5 p.m. in Room 3720, U.S. Department of Commerce, 14th and... received. Decision: Approved. No instrument of equivalent scientific value to the foreign instrument, for...

Analytics and Action in Afghanistan

DTIC Science & Technology

2010-09-01

rests on rational technology , and ultimately on scientific knowledge. No country could be modern without being eco- nomically advanced or...backwardness to enlight - ened modernity. Underdeveloped countries had failed to progress to what Max Weber called rational legalism because of the grip...Douglas Pike, Viet Cong: The Organization and Techniques of the National Liberation Front of South Vietnam (Boston: Massachusetts Institute of Technology

An Intelligent Hierarchical Decision Architecture for Operational Test and Evaluation

DTIC Science & Technology

1996-05-01

Results .......................................... 60 3.4 CONTRIBUTION...FCM Fuzzy Cognitive Map FMEA Failure Modes and Effects Analysis HWIL Hardware-in-the-Loop IBL Increase in Break Locks xiv IDA Institute for Defense... 60 .5 .40 3 .25 0.21 0.26 Figure 8 PROD-ALL COMMFFY Compositional Method .65 . 7 5 . 60 M 0.67 Figure 9 PROD-MAX COMMFFY Compositional Method 49

Picophytoplankton physiology and the microbial loop

NASA Astrophysics Data System (ADS)

Stawiarski, Beate

2013-04-01

Physiological observations are needed for a better understanding of the complexity of marine ecosystem processes. This information is important for a better model formulation and parameterisation to identify the consequences of, and feedbacks to, global change and to make future projections. Picophytoplankton form the smallest component of the phytoplankton community (˜ 3μm) and show a substantial contribution to phytoplankton biomass in oligotrophic oceans. Here they also have an important function as primary producers in the microbial loop. They include cyanobacteria, represented by Prochlorococcus and Synechococcus, and picoeukaryotes. The aim of this project is to achieve a better representation of picophytoplankton in the global biogeochemical model PlankTOM 10. PlankTOM 10 simplifies the complex ecosystem into 10 conceptual groups also known as plankton functional types (PFTs). These groups of organisms are defined by physiological and biochemical parameters (6 of phytoplankton, 3 of zooplankton and 1 of bacteria). Furthermore, the question will be addressed, whether picophytoplankton are typical K-strategists with low minimum nutrient and high maximum chlorophyll quota relative to carbon, or by having superior nutrient uptake kinetics and light harvesting (high αChl). Laboratory experiments showed that the smaller picoprokaryotes respond faster to increasing light intensities than their picoeukaryotic counterpart. Preliminary data show that the initial slope of the photosynthesis vs. irradiance curve (αChl) of picoprokaryotes is about 1.5 times higher than of picoeukaryotes. This is consistent with their common distribution at the deep chlorophyll maximum. The maximum chlorophyll quota are not significantly different. Temperature experiments confirmed that the maximum growth rates of picophytoplankton at the optimum temperature (0.47 ± 0.17 d-1 for prokaryotes and 1.05 ± 0.47 d-1 for eukaryotes) are significantly lower than of diatoms (1.57 ± 0.73 d-1, Chollet et al. in prep.) and not significantly different from coccolithophores (0.68 ± 0.10 d-1, Buitenhuis et al. 2008), consistent with the characterisation of picophytoplanton as K-strategists. Their optimum temperatures were found to be 22.7 ± 2.0 ° C for prokaryotes and 23.6 ± 3.1 ° C for eukaryotes. Nutrient limitation experiments will be conducted to characterize the nutrient uptake and elemental composition of picophytoplankton. Finally the results of all experiments will then be used to improve the representation of picophytoplankton in PlankTOM10, evaluated against a recently compiled global database of picophytoplankton biomass.

Pan-STARRS1: Status, Science, and Public Data Release

NASA Astrophysics Data System (ADS)

Chambers, Kenneth C.

2013-01-01

PS1, the Pan-STARRS1 Telescope is entering its third year of operations. Operations of the PS1 System include the Observatory, Telescope, 1.4 Gigapixel Camera, Image Processing Pipeline , PSPS relational database and reduced science product software servers. The PS1 Surveys include: (1) A 3pi Steradian Survey, (2) A Medium Deep survey of 10 PS1 footprints spaced around the sky; (3) A solar system survey optimized for Near Earth Objects, (4) a Stellar Transit Survey; and (5) a Deep Survey of M31. The PS1 3pi Survey has now covered most of the sky north of dec=-30 with 8 to 10 visits in five bands: g,r,i,z and y or over ~45 epochs per point on sky. The performance of the PS1 system, sky coverage, cadence, and data quality of the surveys will be presented as well as progress in reprocessing of the data taken to date and plans for serving the data to the public. A summary of science highlights will be included. The PS1 Science Consortium consists of The Institute for Astronomy at the University of Hawai'i in Manoa, the Max Planck Institute for Astronomy, Heidelberg and the Max Planck Institute for Extraterrestrial Physics, Garching, The Johns Hopkins University, the University of Durham, the University of Edinburgh, the Queen's University Belfast, the Harvard-Smithsonian Center for Astrophysics, the Los Cumbres Observatory Global Telescope Network Incorporated, and the National Central University of Taiwan, NASA, and NSF.

The PS1 Science Mission - Status and Results

NASA Astrophysics Data System (ADS)

Chambers, Kenneth C.

2013-06-01

PS1, the Pan-STARRS1 Telescope is in its last year of the PS1 Science Mission. Operations of the PS1 System include the Observatory, Telescope, 1.4 Gigapixel Camera, Image Processing Pipeline , PSPS relational database and reduced science product software servers. The PS1 Surveys include: (1) A 3pi Steradian Survey, (2) A Medium Deep survey of 10 PS1 footprints spaced around the sky; (3) A solar system survey optimized for Near Earth Objects, (4) a Stellar Transit Survey; and (5) a Deep Survey of M31. The PS1 3pi Survey has now covered the sky north of dec=-30 with 8 to 12 visits in five bands: g,r,i,z and y or over ~45 epochs per point on sky. The performance of the PS1 system, sky coverage, cadence, and data quality of the surveys will be presented as well as progress in reprocessing of the data taken to date and plans for serving the data to the public. A summary of science highlights will be included. The PS1 Science Consortium consists of The Institute for Astronomy at the University of Hawai'i in Manoa, the Max Planck Institute for Astronomy, Heidelberg and the Max Planck Institute for Extraterrestrial Physics, Garching, The Johns Hopkins University, the University of Durham, the University of Edinburgh, the Queen's University Belfast, the Harvard-Smithsonian Center for Astrophysics, the Los Cumbres Observatory Global Telescope Network Incorporated, and the National Central University of Taiwan, NASA, and NSF.

Development of a Novel, Highly Quantitative In Vivo Model for the Study of Biofilm-Impaired Cutaneous Wound Healing

DTIC Science & Technology

2011-01-01

established on microbiologically naıve tissues (such as in endocarditis or cystic fibrosis). Whether on damaged heart valves or poorly functioning respiratory...time. Although wound infections represent a spectrum of bacterial phenotypes, involving bacteria in both the plank- tonic and biofilm phases, we use...our model to study differ- ences in planktonic- and biofilm-dominant infections , which are classically associated with acute and chronic wound

On the Role of Built-in Electric Fields on the Ignition of Oxide Coated NanoAluminum: Ion Mobility versus Fickian Diffusion

DTIC Science & Technology

2010-01-01

on Al ion diffu- sion can be computed using the Nernst –Planck equation . The Nernst –Plank equation is given in Eq. 4,22 J = − D dC dx − zFDC RT d dx...The use of the bulk diffusion equation is reason- able since during the time scales considered the movement of only the atoms initially on the surface

Recovering from Katrina. Air Force Civil Engineer, Volume 13, Number 3, 2005

DTIC Science & Technology

2005-01-01

Texas, Col Patrick is responsible for providing functional leadership and technical guidance to civil engineer units supporting the more than...delivery of facilities prior to the Wing’s initial operational capability date. Attitude was affected by strong leadership from a senior executive...Warfare Ramping Up for AM-2’s Replacement Mr. Joe D. Fisher ACC/A7XX History of AM-2 AM-2 aluminum matting, an evolution of the pierced steel plank

European Scientific Notes. Volume 39, Number 2.

DTIC Science & Technology

1985-02-01

activated guinea pig perito- laboratory facilities are excellent, as neal macrophages and of normal alveolar are the research scientists in Thoenen’s...macrophages of the guinea pig , TF department. There is close collaboration isolated from human lymphocytes seems to with the Max Planck Institute of Bio...representative of the use in production of prototype software. Commerce Department for industrial Included are cross-reference tools, assessment in

MACv2-SP: a parameterization of anthropogenic aerosol optical properties and an associated Twomey effect for use in CMIP6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stevens, Bjorn; Fiedler, Stephanie; Kinne, Stefan

A simple plume implementation of the second version (v2) of the Max Planck Institute Aerosol Climatology, MACv2-SP, is described. MACv2-SP provides a prescription of anthropogenic aerosol optical properties and an associated Twomey effect. It was created to provide a harmonized description of post-1850 anthropogenic aerosol radiative forcing for climate modeling studies. MACv2-SP has been designed to be easy to implement, change and use, and thereby enable studies exploring the climatic effects of different patterns of aerosol radiative forcing, including a Twomey effect. MACv2-SP is formulated in terms of nine spatial plumes associated with different major anthropogenic source regions. The shapemore » of the plumes is fit to the Max Planck Institute Aerosol Climatology, version 2, whose present-day (2005) distribution is anchored by surface-based observations. Two types of plumes are considered: one predominantly associated with biomass burning, the other with industrial emissions. These differ in the prescription of their annual cycle and in their optical properties, thereby implicitly accounting for different contributions of absorbing aerosol to the different plumes. A Twomey effect for each plume is prescribed as a change in the host model's background cloud-droplet population density using relationships derived from satellite data. Year-to-year variations in the amplitude of the plumes over the historical period (1850–2016) are derived by scaling the plumes with associated national emission sources of SO 2 and NH 3. Experiments using MACv2-SP are performed with the Max Planck Institute Earth System Model. The globally and annually averaged instantaneous and effective aerosol radiative forcings are estimated to be -0.6 and -0.5 W m -2, respectively. Forcing from aerosol–cloud interactions (the Twomey effect) offsets the reduction of clear-sky forcing by clouds, so that the net effect of clouds on the aerosol forcing is small; hence, the clear-sky forcing, which is more readily measurable, provides a good estimate of the total aerosol forcing.« less

MACv2-SP: a parameterization of anthropogenic aerosol optical properties and an associated Twomey effect for use in CMIP6

NASA Astrophysics Data System (ADS)

Stevens, Bjorn; Fiedler, Stephanie; Kinne, Stefan; Peters, Karsten; Rast, Sebastian; Müsse, Jobst; Smith, Steven J.; Mauritsen, Thorsten

2017-02-01

A simple plume implementation of the second version (v2) of the Max Planck Institute Aerosol Climatology, MACv2-SP, is described. MACv2-SP provides a prescription of anthropogenic aerosol optical properties and an associated Twomey effect. It was created to provide a harmonized description of post-1850 anthropogenic aerosol radiative forcing for climate modeling studies. MACv2-SP has been designed to be easy to implement, change and use, and thereby enable studies exploring the climatic effects of different patterns of aerosol radiative forcing, including a Twomey effect. MACv2-SP is formulated in terms of nine spatial plumes associated with different major anthropogenic source regions. The shape of the plumes is fit to the Max Planck Institute Aerosol Climatology, version 2, whose present-day (2005) distribution is anchored by surface-based observations. Two types of plumes are considered: one predominantly associated with biomass burning, the other with industrial emissions. These differ in the prescription of their annual cycle and in their optical properties, thereby implicitly accounting for different contributions of absorbing aerosol to the different plumes. A Twomey effect for each plume is prescribed as a change in the host model's background cloud-droplet population density using relationships derived from satellite data. Year-to-year variations in the amplitude of the plumes over the historical period (1850-2016) are derived by scaling the plumes with associated national emission sources of SO2 and NH3. Experiments using MACv2-SP are performed with the Max Planck Institute Earth System Model. The globally and annually averaged instantaneous and effective aerosol radiative forcings are estimated to be -0.6 and -0.5 W m-2, respectively. Forcing from aerosol-cloud interactions (the Twomey effect) offsets the reduction of clear-sky forcing by clouds, so that the net effect of clouds on the aerosol forcing is small; hence, the clear-sky forcing, which is more readily measurable, provides a good estimate of the total aerosol forcing.

Cooperative Projects - Challenges and Opportunities

NASA Astrophysics Data System (ADS)

Schubotz, Wiebke; Brücher, Tim; Vamborg, Freja

2017-04-01

Today's research in Germany is often organized in large projects and collaborations, so-called cooperative projects ("Verbundprojekte" in German). These projects are defined by a large number of members (more than 50) and participating institutes, e.g. institutes of research organizations such as the Max-Planck society and the Leibniz association, Helmholtz centres, and universities. For coordination purposes these projects usually have a general project manager or project coordinator close to the speaker of the project. Despite this overarching position, it is often challenging for the project manager to really overview the entire project as he is, for example, not involved in the individual institute's recruitment processes or research connections to other institutes via other projects. Additionally, there is neither a formal obligation for the principal investigators and project scientists to report changes within their sub-projects, nor any formal dependency between these sub-projects and the coordination office to ensure a contemporary update of changes and progress in their specific tasks of the project. Therefore, the idea of a coordinating position to oversee the entire cooperative project is sometimes difficult to reach. Furthermore, project managers usually have no formal connection to other project managers. This means that recurrent tasks, for which cooperation between project managers would be helpful, need to be reinvented for each project anew. Due to the lack of this more formalized cooperation between project managers, acquired expertise is often lost. We will illustrate the challenges of this kind of project management based on projects at the Max Planck Institute for Meteorology (Hamburg) and the Helmholtz Centre for Ocean Research (GEOMAR, Kiel), but also point out opportunities that arise within a large collaboration of partners. Moreover, we present an approach to coordinate management processes in order to overcome some of the aforementioned challenges across several cooperative projects - a virtual centre for earth system science management (CESSMA).

The Influence of Ridge Geometry at the Ultraslow-Spreading Southwest Indiean Ridge (9 deg - 25 deg E): Basalt Composition Sensitivity to Variations in Source and Process

DTIC Science & Technology

2006-02-01

East Pacific Rise , 5 degrees 30’-14 degrees 30’ N , Natures, 322, 422-429. Langmuir, C. H., E. M. Klein, and T. Plank (1992...Mantle source heterogeneity and melting processes beneath seafloor spreading centers: The East Pacific Rise , 18 degrees -19 degrees S, Journal of... East Pacific Rise , Aumento, F., and H. Loubat, The Mid-Atlantic Ridge Near Proc. Ocean Drill. Program Sci. Results, 147, 103-134,

Air Force Heroes in Vietnam

DTIC Science & Technology

1979-01-01

gave me a little more weight on the brakes. I think I must have been skidding on that steel planking . It was a little bit slick from the dampness. I...have a history of outstanding performance and a unique blend of flying experience and leadership ability. To be the boss of a squadron in combat is...hitting something they wanted to hang on to. it was a vital target and its loss would hurt them." Merl and his backseater, Captain Kevin "Mike" Gilroy

The Durability of Cultural Influences: How American Foreign Policy Reinforced Historical Biases in El Salvador

DTIC Science & Technology

2008-05-01

America Since 1920,” Journal of Latin American Studies, 1983: 276. 11 Kevin Sullivan, “El Salvador: On Unfinished Road to Reform; Despite Being...different than those of President Carter. In fact, a substantial part of his party plank cited key differences between his and the ex-president’s Central...true: Castro himself was influential with FMLN leadership ; in fact, the FMLN formed at his urging.42 The full extent to which Castro, the Soviets or

Lessons from disaster: Creating a business continuity plan that really works.

PubMed

Hatton, Tracy; Grimshaw, Eleanor; Vargo, John; Seville, Erica

Business Continuity Planning (BCP) is well established as a key plank in an organisation's risk management process. But how effective is BCP when disaster strikes? This paper examines the experiences of organisations following the 2010-11 Canterbury, New Zealand earthquakes. The study finds that BCP was helpful for all organisations interviewed but more attention is needed on the management of societal and personal impacts; development of employee resilience, identification of effective crisis leaders; right-sizing plans and planning to seize opportunities post-disaster.

Preparing the Fleet for the F-35B

DTIC Science & Technology

2012-02-06

from forward sites, a similar argument was made in the early 1970s by the “ plank holders” of the AV-8B program. vi In the Spring of 2010, USMC...Flying Shame.” Such press caused significant concern in the USMC’s leadership to attempt and mitigate possible risk in the operation of the aircraft...www.armedforcesjournal.com/2010/10/4765181/ (accessed January 14, 2012). Sack, Kevin and Allan C. Miller. “An Abundance of Crash-Causing Glitches.” Los Angeles

The Russian Military in the Year 2000

DTIC Science & Technology

1992-12-01

Contrao!zions, Mosow. scc ennava Mysl, in Russian, no. 6-7, Jun-Ju’l -, o. 2-’, (JPRS-7MT-𔃼-’i!-L, 14 September 1992, p. 4). ;’ovennvv En ...going to war and influences the ways of waging it. It also influences the planning and conduct of war, determining, for example, when, where and how...interesting to note that the conservative communist/nationalist faction of parliament has not had the influence to include this plank in the statement and

Research on Upgrading Structures for Host and Risk Area Shelters

DTIC Science & Technology

1982-09-01

both "as-built" and upgraded configurations. These analysis and prediction techniques have been applied to floors and roofs constructed of many...scale program and were previously applied to full-scale wood floor tests (Ref. 2). TEST ELEMENTS AND PROCEDURES Three tests were conducted on 8-inch...weights. A 14,000-lb crane counterweight was used for the preload, applying a load of 7,000 lb to each one-third point on the plank. The drop weight was

Wood industrial application for quality control using image processing

NASA Astrophysics Data System (ADS)

Ferreira, M. J. O.; Neves, J. A. C.

1994-11-01

This paper describes an application of image processing for the furniture industry. It uses an input data, images acquired directly from wood planks where defects were previously marked by an operator. A set of image processing algorithms separates and codes each defect and detects a polygonal approach of the line representing them. For such a purpose we developed a pattern classification algorithm and a new technique of segmenting defects by carving the convex hull of the binary shape representing each isolated defect.

Gould on species, metaphysics and macroevolution: A critical appraisal.

PubMed

Boucher, Sandy C

2017-04-01

Stephen Jay Gould's views on the ontology of species were an important plank of his revisionist program in evolutionary theory. In this paper I cast a critical eye over those views. I focus on three central aspects of Gould's views on species: the relation between the Darwinian and the metaphysical notions of individuality, the relation between the ontology of species and macroevolution, and the issue of contextualism and conventionalism about the metaphysics of species. Copyright © 2017 Elsevier Ltd. All rights reserved.

Intercomparison study of atmospheric methane and carbon dioxide concentrations measured at the Ebre River Delta Station

NASA Astrophysics Data System (ADS)

Occhipinti, Paola; Morguí, Josep Anton; Àgueda, Alba; Batet, Oscar; Borràs, Sílvia; Cañas, Lídia; Curcoll, Roger; Grossi, Claudia; Nofuentes, Manel; Vazquez, Eusebi; Rodó, Xavier

2015-04-01

In the framework of the ClimaDat project, IC3 has established a network of eight monitoring stations across the Iberian Peninsula and the Canarian Archipelago with the aim of studying climate processes. The monitoring station at the Ebre River Delta (DEC3) is located in the Ebre River Delta Natural Park (40° 44' N; 0° 47' E) and it is characterized by the typical North-Western Mediterranean climate. Since 2013, atmospheric greenhouse gases (GHG) and 222Rn tracer gas together with the meteorological parameters are continuously measured from a 10 m a.g.l. height tower. Atmospheric GHG (CO2, CH4, CO and N2O) concentrations are determined using a Picarro analyzer G2301 (CO2 and CH4) and a modified gas chromatograph (GC) Agilent 6890N (CO2, CH4, CO and N2O). Open data access is available from the www.climadat.es website. Data collected at the DEC3 station are also submitted to the InGOS platform since this station is part of the InGOS European infrastructure project. Researchers from the Laboratory of the Atmosphere and the Oceans (LAO) at IC3 have performed an intercomparison study at the DEC3 site between three different Picarro analyzers (two Picarro G2301 and one Picarro G2301M), a Los Gatos Research (LGR) analyzer and the GC system already installed at the station. The aim of this study is to compare and assess the measuring agreement between the four optical gas analyzers and the GC. In the first part of the experiment, all instruments have been calibrated using NOAA gases as primary standards analyzing five Praxair provided targets to evaluate the precision of the measuring instruments. Max Plank Institute (MPI) gases have been used as secondary standards for the GC whereas Praxair provided tanks are used as secondary standards for the Picarro and the LGR analyzers. In the second part of the experiment, atmospheric GHG were measured from natural atmospheric air taken from a 10 m a.g.l. inlet. Daily cycles of GHG measurements were carried out using different instruments simultaneously over a period of 24 hours, coupling the GC with a combination of two optical analyzers per time. Precision results together with the evaluation of the advantages and drawbacks of the use of these different GHG measuring instruments will be discussed. The intercomparison study here presented will be implemented by carrying it out at each of the eight ClimaDat monitoring stations in Spain, representing a quality control system for the analysis of GHG in the ClimaDat network.

Fluorodeoxyglucose Uptake on Positron Emission Tomography Is a Useful Predictor of Long-Term Pain Control After Palliative Radiation Therapy in Patients With Painful Bone Metastases: Results of a Single-Institute Prospective Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tahara, Takatoshi, E-mail: taka.t-may7@med.Tottori-u.ac.jp; Fujii, Shinya; Ogawa, Toshihide

Purpose: To determine whether fluorodeoxyglucose positron emission tomography (FDG-PET) before and after palliative radiation therapy (RT) can predict long-term pain control in patients with painful bone metastases. Methods and Materials: Thirty-one patients with bone metastases who received RT were prospectively included. Forty painful metastatic treatment fields were evaluated. All patients had undergone pre-RT and post-RT PET/CT scanning. We evaluated the relationships between the pre-RT, post-RT, and changes in maximum standardized uptake value (SUV{sub max}) and the pain response, and between SUV{sub max} and pain relapse of the bone metastases in the treatment field. In addition, we compared the SUV{sub max}more » according to the length of time from the completion of RT to pain relapse of the bone metastases. Results: Regarding the pain response at 4 weeks after the completion of RT, there were 36 lesions of 27 patients in the responder group and 4 lesions of 4 patients in the nonresponder group. Changes in the SUV{sub max} differed significantly between the responder and nonresponder groups in both the early and delayed phases (P=.0292 and P=.0139, respectively), but no relationship was observed between the pre-RT and post-RT SUV{sub max} relative to the pain response. The responder group was evaluated for the rate of relapse. Thirty-five lesions of 26 patients in the responder group were evaluated, because 1 patient died of acute renal failure at 2 months after RT. Twelve lesions (34%) showed pain relapse, and 23 lesions (66%) did not. There were significant differences between the relapse and nonrelapse patients in terms of the pre-RT (early/delayed phases: P<.0001/P<.0001), post-RT (P=.0199/P=.0261), and changes in SUV{sub max} (P=.0004/P=.004). Conclusions: FDG-PET may help predict the outcome of pain control in the treatment field after palliative RT for painful bone metastases.« less

Gauge Invariance and the Goldstone Theorem

NASA Astrophysics Data System (ADS)

Guralnik, Gerald S.

This paper was originally created for and printed in the "Proceedings of seminar on unified theories of elementary particles" held in Feldafing, Germany from July 5 to 16, 1965 under the auspices of the Max-Planck-Institute for Physics and Astrophysics in Munich. It details and expands upon the 1964 Guralnik, Hagen, and Kibble paper demonstrating that the Goldstone theorem does not require physical zero mass particles in gauge theories.

Establishing daily quality control (QC) in screen-film mammography using leeds tor (max) phantom at the breast imaging unit of USTH-Benavides Cancer Institute

NASA Astrophysics Data System (ADS)

Acaba, K. J. C.; Cinco, L. D.; Melchor, J. N.

2016-03-01

Daily QC tests performed on screen film mammography (SFM) equipment are essential to ensure that both SFM unit and film processor are working in a consistent manner. The Breast Imaging Unit of USTH-Benavides Cancer Institute has been conducting QC following the test protocols in the IAEA Human Health Series No.2 manual. However, the availability of Leeds breast phantom (CRP E13039) in the facility made the task easier. Instead of carrying out separate tests on AEC constancy and light sensitometry, only one exposure of the phantom is done to accomplish the two tests. It was observed that measurements made on mAs output and optical densities (ODs) using the Leeds TOR (MAX) phantom are comparable with that obtained from the usual conduct of tests, taking into account the attenuation characteristic of the phantom. Image quality parameters such as low contrast and high contrast details were also evaluated from the phantom image. The authors recognize the usefulness of the phantom in determining technical factors that will help improve detection of smallest pathological details on breast images. The phantom is also convenient for daily QC monitoring and economical since less number of films is expended.

Social science as a "weapon of the weak": Max Weinreich, the Yiddish Scientific Institute, and the study of culture, personality, and prejudice.

PubMed

Zenderland, Leila

2013-12-01

This essay examines Max Weinreich's efforts to turn "culture and personality studies" into social and psychological weapons that could be used to combat the effects of prejudice. It focuses on language choice, audience, and purpose in the production of such knowledge by and for a Yiddish-speaking Eastern European population. During the 1930s, Weinreich led the Yiddish Scientific Institute, a research organization headquartered in Poland but affiliated with neither a state nor a university. He was profoundly influenced by a year spent at Yale and a trip through the American South visiting segregated African-American universities. In his 1935 study Der veg tsu undzer yugnt [The Way to Our Youth], Weinreich blended European, Soviet, American, and African-American research traditions to examine the effects of prejudice on child and adolescent development; he also considered the ways members of "despised minorities" could use such science. In 1940 he fled to New York and in 1946 published Hitler's Professors, the first book analyzing the uses of the human sciences to advance Nazi state-sponsored antisemitism. In examining Weinreich's Yiddish and English writings, this essay explores the broader relationship of social science not only to state power but also to statelessness and powerlessness.

[From psychotherapy to psychoanalysis: Max Levy-Suhl (1876-1947)].

PubMed

Hermanns, Ludger M; Schröter, Michael; Stroeken, Harry

2014-01-01

From psychotherapy to psychoanalysis: Max Levy-Suhl (1876-1947). Levy-Suhl can be considered one of the great practising psychotherapists in early 20th century Berlin. He was active in various fields, including ophthalmology, forensic adolescent psychiatry and hypnosis. Prominent among his publications were two handbooks of psychotherapeutic methods. His attitude towards psychoanalysis shifted from initial criticism to acceptance. Ca. 1930 he experienced some kind of conversion, resulting in his training at the Berlin Institute and becoming a member of the German Psychoanalytic Society. As a Jew being forced to emigrate in 1933, Levy-Suhl turned to the Netherlands where he had a psychoanalytic children's home in Amersfoort, followed by an analyst's practice in Amsterdam. He survived the German occupation, but apparently as a broken man. After the war he committed suicide.--The paper is complemented by an appendix, containing documents and an extensive bibliography.

Identification and analysis of recent temporal temperature trends for Dehradun, Uttarakhand, India

NASA Astrophysics Data System (ADS)

Piyoosh, Atul Kant; Ghosh, Sanjay Kumar

2018-05-01

Maximum and minimum temperatures (T max and T min) are indicators of changes in climate. In this study, observed and gridded T max and T min data of Dehradun are analyzed for the period 1901-2014. Observed data obtained from India Meteorological Department and National Institute of Hydrology, whereas gridded data from Climatic Research Unit (CRU) were used. Efficacy of elevation-corrected CRU data was checked by cross validation using data of various stations at different elevations. In both the observed and gridded data, major change points were detected using Cumulative Sum chart. For T max, change points occur in the years 1974 and 1997, while, for T min, in 1959 and 1986. Statistical significance of trends was tested in three sub-periods based on change points using Mann-Kendall (MK) test, Sen's slope estimator, and linear regression (LR) method. It has been found that both the T max and T min have a sequence of rising, falling, and rising trends in sub-periods. Out of three different methods used for trend tests, MK and SS have indicated similar results, while LR method has also shown similar results for most of the cases. Root-mean-square error for actual and anomaly time series of CRU data was found to be within one standard deviation of observed data which indicates that the CRU data are very close to the observed data. The trends exhibited by CRU data were also found to be similar to the observed data. Thus, CRU temperature data may be quite useful for various studies in the regions of scarcity of observational data.

Intrathoracic pressure impulse predicts pulmonary contusion volume in ballistic blunt thoracic trauma.

PubMed

Prat, Nicolas; Rongieras, Frédéric; Voiglio, Eric; Magnan, Pascal; Destombe, Casimir; Debord, Eric; Barbillon, Franck; Fusai, Thierry; Sarron, Jean-Claude

2010-10-01

Blunt thoracic trauma including behind armour blunt trauma or impact from a less lethal kinetic weapon (LLKW) projectile may cause injuries, including pulmonary contusions that can result in potentially lethal secondary complications. These lung injuries may be caused by intrathoracic pressure waves. The aim of this study was to observe dynamic changes in intrathoracic hydrostatic pressure during ballistic blunt thoracic trauma and to find correlations between these hydrostatic pressure parameters (especially the impulse parameter) and physical damages. Thirty anesthetized pigs sustained a blunt thoracic trauma. In group 1 (n = 20), pigs were protected by a National Institute of Justice class III or IV bulletproof vest and shot with 7.62 NATO bullets. In group 2 (n = 10), pigs were shot by an LLKW. Intrathoracic pressure was recorded with an intraesophageal pressure sensor and three parameters were determined: intrathoracic maximum pressure, intrathoracic maximum pressure impulse (PI(max)), and the Pd.P/dt(max), derived from Viano's viscous criterion. Relative right lower lung lobe contusion volume was also measured. Different thoracic loading conditions were obtained. PI(max) best correlated with relative pulmonary contusion volume (R² = 0.64 and p < 0.0001). This result was homogenous for all experiments and was not related to the type of chest impact (LLKW-induced trauma or behind armour blunt trauma). The PI(max) is a good predictor of pulmonary contusion volume after ballistic blunt thoracic trauma. It is a useful criterion when the kinetic energy record or thoracic wall displacement data are unavailable, and the recording and calculation of this physical value are quite simple on animals.

Predictors of Urinary Morbidity in Cs-131 Prostate Brachytherapy Implants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Ryan P., E-mail: smithrp@upmc.edu; Jones, Heather A.; Beriwal, Sushil

2011-11-01

Purpose: Cesium-131 is a newer radioisotope being used in prostate brachytherapy (PB). This study was conducted to determine the predictors of urinary morbidity with Cs-131 PB. Methods and Materials: A cohort of 159 patients underwent PB with Cs-131 at our institution and were followed by using Expanded Prostate Cancer Index Composite (EPIC) surveys to determine urinary morbidity over time. EPIC scores were obtained preoperatively and postoperatively at 2 and 4 weeks, and 3 and 6 months. Different factors were evaluated to determine their individual effect on urinary morbidity, including patient characteristics, disease characteristics, treatment, and dosimetry. Multivariate analysis of covariancemore » was carried out to identify baseline determinants affecting urinary morbidity. Factors contributing to the need for postoperative catheterization were also studied and reported. Results: At 2 weeks, patient age, dose to 90% of the organ (D90), bladder neck maximum dose (D{sub max}), and external beam radiation therapy (EBRT) predicted for worse function. At 4 weeks, age and EBRT continued to predict for worse function. At the 3-month mark, better preoperative urinary function, preoperative alpha blockers, bladder neck D{sub max}, and EBRT predicted for worse urinary morbidity. At 6 months, better preoperative urinary function, preoperative alpha blockers, bladder neck D{sub max}, and EBRT were predictive of increased urinary problems. High bladder neck D{sub max} and poor preoperative urinary function predicted for the need for catheterization. Conclusions: The use of EBRT plus Cs-131 PB predicts for worse urinary toxicity at all time points studied. Patients should be cautioned about this. Age was a consistent predictor of worsened morbidity immediately following Cs-131 PB, while bladder D{sub max} was the only consistent dosimetric predictor. Paradoxically, patients with better preoperative urinary function had worse urinary morbidity at 3 and 6 months, consistent with recently published literature.« less

Comparing Change in Anterior Curvature after Corneal Cross-Linking Using Scanning-Slit and Scheimpflug Technology.

PubMed

Lang, Paul Z; Thulasi, Praneetha; Khandelwal, Sumitra S; Hafezi, Farhad; Randleman, J Bradley

2018-05-02

To evaluate the correlation between anterior axial curvature difference maps following corneal cross-linking (CXL) for progressive keratoconus obtained from Scheimpflug-based tomography and Placido-based topography. Between-devices reliability analysis of randomized clinical trial data METHODS: Corneal imaging was collected at a single center institution pre-operatively and at 3, 6, and 12 months post-operatively using Scheimpflug-based tomography (Pentacam, Oculus Inc., Lynnwood, WA) and Scanning-slit, Placido-based topography (Orbscan II, Bausch & Lomb, Rochester, NY) in patients with progressive keratoconus receiving standard protocol CXL (3mW/cm 2 for 30 minutes). Regularization index (RI), absolute maximum keratometry (K Max), and change in (ΔK Max) were compared between the two devices at each time point. 51 eyes from 36 patients were evaluated at all time points. values were significantly different at all time points [56.01±5.3D Scheimpflug vs. 55.04±5.1D scanning-slit pre-operatively (p=0.003); 54.58±5.3D Scheimpflug vs. 53.12±4.9D scanning-slit at 12 months (p<0.0001)] but strongly correlated between devices (r=0.90-0.93) at all time points. The devices were not significantly different at any time point for either ΔK Max or RI but were poorly correlated at all time points (r=0.41-0.53 for ΔK Max, r=0.29-0.48 for RI). At 12 months, 95% LOA was 7.51D for absolute, 8.61D for ΔK Max, and 19.86D for RI. Measurements using Scheimpflug and scanning-slit Placido-based technology are correlated but not interchangeable. Both devices appear reasonable for separately monitoring the cornea's response to CXL; however, caution should be used when comparing results obtained with one measuring technology to the other. Copyright © 2018 Elsevier Inc. All rights reserved.

Is My Exercise Partner Similar Enough? Partner Characteristics as a Moderator of the Köhler Effect in Exergames.

PubMed

Forlenza, Samuel T; Kerr, Norbert L; Irwin, Brandon C; Feltz, Deborah L

2012-12-01

Recent research has shown the Köhler motivation gain effect (working at a task with a more capable partner where one's performance is indispensable to the group) leads to greater effort in partnered exercise videogame play. The purpose of this article was to examine potential moderators of the Köhler effect by exploring dissimilarities in one's partner's appearance, namely, having an older partner (compared with a same-age partner) and having a heavier-weight partner (compared with a same-weight partner). One hundred fifty-three male and female college students completed a series of plank exercises using the "EyeToy: Kinetic™" for the PlayStation(®) 2 (Sony, Tokyo, Japan). Participants first completed the exercises individually and, after a rest, completed the same exercises with a virtually present partner. Exercise persistence, subjective effort, self-efficacy beliefs, enjoyment, and intentions to exercise were recorded and analyzed. A significant Köhler motivation gain was observed in all partner conditions (compared with individual controls) such that participants with a partner held the plank exercises longer (P<0.001) and reported higher subjective effort (P<0.01). These results were unmoderated by partner's age and weight, with one exception: Males tended to persist longer when paired with an obese partner (P=0.08). These results suggest that differences in age and weight do not attenuate the Köhler effect in exergames and may even strengthen it.

Core stability: implications for dance injuries.

PubMed

Rickman, Ashley M; Ambegaonkar, Jatin P; Cortes, Nelson

2012-09-01

Dancers experience a high incidence of injury due to the extreme physical demands of dancing. The majority of dance injuries are chronic in nature and occur in the lower extremities and low back. Researchers have indicated decreased core stability (CS) as a risk factor for these injuries. Although decreased CS is suggested to negatively affect lower extremity joint motion and lumbar control during activity, this relationship has not been extensively discussed in previous dance literature. Understanding the relationship between CS and injury risk is important to help reduce dance injury incidence and improve performance. The purposes of this review were to discuss: 1. the core and components of CS, 2. the relationship between CS and injury, 3. CS assessment techniques, and 4. future dance CS research areas. CS is the integration of passive (non-contractile), active (contractile), and neural structures to minimize the effects of external forces and maintain stability. CS is maintained by a combination of muscle power, strength, endurance, and sensory-motor control of the lumbopelvic-hip complex. CS assessments include measuring muscle strength and power using maximal voluntary isometric and isokinetic contractions and measuring endurance using the Biering-Sorensen, plank, and lateral plank tests. Measuring sensory-motor control requires specialized equipment (e.g., balance platforms). Overall, limited research has comprehensively examined all components of CS together and their relationships to injury. Rather, previous researchers have separately examined core power, strength, endurance, or sensory-motor control. Future researchers should explore the multifactorial role of CS in reducing injury risk and enhancing performance in dancers.

Screen-based sedentary behavior and associations with functional strength in 6-15 year-old children in the United States.

PubMed

Edelson, Lisa R; Mathias, Kevin C; Fulgoni, Victor L; Karagounis, Leonidas G

2016-02-04

Physical strength is associated with improved health outcomes in children. Heavier children tend to have lower functional strength and mobility. Physical activity can increase children's strength, but it is unknown how different types of electronic media use impact physical strength. Data from the NHANES National Youth Fitness Survey (NNYFS) from children ages 6-15 were analyzed in this study. Regression models were conducted to determine if screen-based sedentary behaviors (television viewing time, computer/video game time) were associated with strength measures (grip, leg extensions, modified pull-ups, plank) while controlling for potential confounders including child age, sex, BMI z-score, and days per week with 60+ minutes of physical activity. Grip strength and leg extensions divided by body weight were analyzed to provide measures of relative strength together with pull-ups and plank, which require lifting the body. The results from the regression models showed the hypothesized inverse association between TV time and all strength measures. Computer time was only significantly inversely associated with the ability to do one or more pull-ups. This study shows that television viewing, but not computer/videogames, is inversely associated with measures of child strength while controlling for child characteristics and physical activity. These findings suggest that "screen time" may not be a unified construct with respect to strength outcomes and that further exploration of the potential benefits of reducing television time on children's strength and related mobility is needed.

Core strength training using a combination of home exercises and a dynamic sling system for the management of low back pain in pre-professional ballet dancers: a case series.

PubMed

Kline, Jessica Beckmann; Krauss, John R; Maher, Sara F; Qu, Xianggui

2013-01-01

Estimates of low back pain prevalence in USA ballet dancers range from 8% to 23%. Lumbar stabilization and extensor muscle training has been shown to act as a hypoalgesic for low back pain. Timing and coordination of multifidi and transverse abdominis muscles are recognized as important factors for spinal stabilization. The purpose of this study was to explore the effects of training methods using home exercises and a dynamic sling system on core strength, disability, and low back pain in pre-professional ballet dancers. Five participants were randomly assigned to start a traditional unsupervised lumbar stabilization home exercise program (HEP) or supervised dynamic sling training to strengthen the core and lower extremities. Measurements were taken at baseline and at weeks 3 and 6 for disability using the patient specific functional scale (PSFS), pain using the Numerical Pain Rating System (NPRS), core strength and endurance using timed plank, side-plank, and bridge positions, and sciatic nerve irritability using the straight leg raise (SLR). Data were analyzed using descriptive statistics. From initial to final measurements, all participants demonstrated an improvement in strength and SLR range, and those with initial pain and disability reported relief of symptoms. These results suggest that dynamic sling training and a HEP may help to increase strength, decrease pain, and improve function in dancers without aggravating sciatic nerve irritation.

Relationship of Hip and Trunk Muscle Function with Single Leg Step-Down Performance: Implications for Return to Play Screening and Rehabilitation.

PubMed

Burnham, Jeremy M; Yonz, Michael C; Robertson, Kaley E; McKinley, Rachelle; Wilson, Benjamin R; Johnson, Darren L; Ireland, Mary Lloyd; Noehren, Brian

2016-11-01

Evaluate the relationship of hip and trunk muscle function with the Single Leg Step-Down test (SLSD). Laboratory study. Biomechanics Laboratory. 71 healthy participants with no history of anterior cruciate ligament (ACL) or lower extremity injury in the last 3 months completed this study (38 males, 33 females; mean 25.49 ± 0.62 years). Hip abduction (HABD), external rotation (HER), and extension (HEXT) peak isometric force were measured. Trunk endurance was measured with plank (PL) and side plank (SPL) tests. SLSD repetitions in 60-s and dynamic knee valgus (VAL) were recorded. PL, SPL, HABD, HER, and HEXT were positively correlated with SLSD repetitions. PL (r = 0.598, p < 0.001) was most correlated with SLSD repetitions, and regression demonstrated that PL (p = 0.001, R 2  = 0.469) was a predictor of SLSD repetitions. VAL trended toward negative correlation with PL and SPL. Sex-specific differences were present, with PL, SPL, HABD, and HER showing stronger relationships with SLSD in females. Hip and trunk muscle function were positively correlated with SLSD performance, and these relationships were strongest in females. PL predicted performance on the SLSD. Further research is needed to investigate the utility of SLSD as a screening or return-to-play test for lower extremity conditions such as ACL injury and patellofemoral pain. Copyright © 2016 Elsevier Ltd. All rights reserved.

AWOB: A Collaborative Workbench for Astronomers

NASA Astrophysics Data System (ADS)

Kim, J. W.; Lemson, G.; Bulatovic, N.; Makarenko, V.; Vogler, A.; Voges, W.; Yao, Y.; Kiefl, R.; Koychev, S.

2015-09-01

We present the Astronomers Workbench (AWOB1), a web-based collaboration and publication platform for a scientific project of any size, developed in collaboration between the Max-Planck institutes of Astrophysics (MPA) and Extra-terrestrial Physics (MPE) and the Max-Planck Digital Library (MPDL). AWOB facilitates the collaboration between geographically distributed astronomers working on a common project throughout its whole scientific life cycle. AWOB does so by making it very easy for scientists to set up and manage a collaborative workspace for individual projects, where data can be uploaded and shared. It supports inviting project collaborators, provides wikis, automated mailing lists, calendars and event notification and has a built in chat facility. It allows the definition and tracking of tasks within projects and supports easy creation of e-publications for the dissemination of data and images and other resources that cannot be added to submitted papers. AWOB extends the project concept to larger scale consortia, within which it is possible to manage working groups and sub-projects. The existing AWOB instance has so far been limited to Max-Planck members and their collaborators, but will be opened to the whole astronomical community. AWOB is an open-source project and its source code is available upon request. We intend to extend AWOB's functionality also to other disciplines, and would greatly appreciate contributions from the community.

ARC-2013-ACD13-0061-007

NASA Image and Video Library

2013-04-18

Kepler News Briefing, held in the Syvertson auditorium at the NASA Ames Research Center. The briefing presented discoveries from the continuing Kepler mission (K2). The team discovered some of the smallest planets found in the habitable zone of two newly discovered planetary systems. Bill Borucki (left), Kepler Scientist, Principal Investigator, NASA Ames Lisa Kaltengger (right), Research Group Leader, Max Planck Institute for Astronomy, Heidelberg Germany and Research Associate, Harvard-Smithsonian Center for Astrophysics, Cambridge Massachusetts.

A DirtI Application for LBT Commissioning Campaigns

NASA Astrophysics Data System (ADS)

Borelli, J. L.

2009-09-01

In order to characterize the Gregorian focal stations and test the performance achieved by the Large Binocular Telescope (LBT) adaptive optics system, two infrared test cameras were constructed within a joint project between INAF (Observatorio Astronomico di Bologna, Italy) and the Max Planck Institute for Astronomy (Germany). Is intended here to describe the functionality and successful results obtained with the Daemon for the Infrared Test Camera Interface (DirtI) during commissioning campaigns.

RRTMGP: A High-Performance Broadband Radiation Code for the Next Decade

DTIC Science & Technology

2015-09-30

NOAA ), Robin Hogan (ECMWF), a number of colleagues at the Max-Planck Institute, and Will Sawyer and Marcus Wetzstein (Swiss Supercomputer Center...somewhat out of date, so that the accuracy of our simplified algorithms can not be thoroughly evaluated. RRTMGP_LW_v0 has been provided to our NASA ...support, RRTMGP_LW_v0, has been completed and distributed to selected colleagues at modeling centers, including NOAA , NCAR, and CSCS. Our colleagues

Studies in Intelligence. Volume 49, Number 4, 2005

DTIC Science & Technology

2005-01-01

solutions required totally new techniques and technology , contractors, and organizations. Using the rapid developments in satellite systems in the 1960s as...both failed came as a postwar shock, especially to those who thought so highly of Klaus Fuchs as a babysitter .17 Conant provides a new look at how...Estimates wrote one of the articles; Max Millikan, of the Massachusetts Institute of Technology , who had helped create economic intelli- gence at the CIA

Application of fuzzy logic-neural network based reinforcement learning to proximity and docking operations

NASA Technical Reports Server (NTRS)

Jani, Yashvant

1992-01-01

As part of the Research Institute for Computing and Information Systems (RICIS) activity, the reinforcement learning techniques developed at Ames Research Center are being applied to proximity and docking operations using the Shuttle and Solar Max satellite simulation. This activity is carried out in the software technology laboratory utilizing the Orbital Operations Simulator (OOS). This interim report provides the status of the project and outlines the future plans.

Matrix De Rham Complex and Quantum A-infinity algebras

NASA Astrophysics Data System (ADS)

Barannikov, S.

2014-04-01

I establish the relation of the non-commutative BV-formalism with super-invariant matrix integration. In particular, the non-commutative BV-equation, defining the quantum A ∞-algebras, introduced in Barannikov (Modular operads and non-commutative Batalin-Vilkovisky geometry. IMRN, vol. 2007, rnm075. Max Planck Institute for Mathematics 2006-48, 2007), is represented via de Rham differential acting on the supermatrix spaces related with Bernstein-Leites simple associative algebras with odd trace q( N), and gl( N| N). I also show that the matrix Lagrangians from Barannikov (Noncommutative Batalin-Vilkovisky geometry and matrix integrals. Isaac Newton Institute for Mathematical Sciences, Cambridge University, 2006) are represented by equivariantly closed differential forms.

Entropy and entropy production in Fokker–Plank equation under the generalized fluctuation–dissipation relation

NASA Astrophysics Data System (ADS)

Guo, Ran

2018-04-01

In this paper, we investigate the definition of the entropy in the Fokker–Planck equation under the generalized fluctuation–dissipation relation (FDR), which describes a Brownian particle moving in a complex medium with friction and multiplicative noise. The friction and the noise are related by the generalized FDR. The entropy for such a system is defined first. According to the definition of the entropy, we calculate the entropy production and the entropy flux. Lastly, we make a numerical calculation to display the results in figures.

The early universe history from contraction-deformation of the Standard Model

NASA Astrophysics Data System (ADS)

Gromov, N. A.

2017-03-01

The elementary particles evolution in the early Universe from Plank time up to several milliseconds is presented. The developed theory is based on the high-temperature (high-energy) limit of the Standard Model which is generated by the contractions of its gauge groups. At the infinite temperature all particles lose masses. Only massless neutral -bosons, massless Z-quarks, neutrinos and photons are survived in this limit. The weak interactions become long-range and are mediated by neutral currents, quarks have only one color degree of freedom.

[German research institute/Max-Planck Institute for psychiatry].

PubMed

Ploog, D

1999-12-01

The Deutsche Forschungsanstalt für Psychiatrie (DFA, German Institute for Psychiatric Research) in Munich was founded in 1917 bel Emil Kraepelin. For a long time it was the only institution in Germany entirely devoted to psychiatric research. Because of its strictly science-oriented and multidisciplinary approach it also became a model for institutions elsewhere. Kraepelin's ideas have certainly had a strong influence on psychiatry in the twentieth century. The fascinating and instructive history of the DFA reflects the central issues and determinants of psychiatric research. First, talented individuals are needed to conduct such research, and there was no lack in this regard. Second, the various topics chosen are dependent on the available methods and resources. And finally, the issues addressed and the ethical standards of the researchers are heavily dependent on the zeitgeist, as is evident in the three epochs of research at the DFA, from 1917 to 1933, from 1933 to 1945, and from the postwar period to the present. With the introduction of molecular biology and neuroimaging techniques into psychiatric research a change in paradigm took place and a new phase of the current epoch began.

8 years of experience in international, interdisciplinary and structured doctoral training in Earth system modelling

NASA Astrophysics Data System (ADS)

Weitz, Antje; Stevens, Bjorn; Marotzke, Jochem

2010-05-01

The mission of the International Max Planck Research School on Earth System Modelling (IMPRS-ESM) is to provide a high quality, modern and structured graduate education to students pursuing a doctoral degree in Earth system modelling. In so doing, the IMPRS-ESM also strives to advance the emerging discipline (or cross-discipline) of Earth system modelling; to provide a framework for attracting the most talented and creative young women and men from around the world to pursue their doctoral education in Germany; to provide advanced as well as specialized academic training and scientific guidance to doctoral students; to encourage academic networking and publication of research results; to better integrate doctoral research at the Max Planck Institute for Meteorology (MPI-M) with education and research at the University of Hamburg and other cooperating institutions. Core elements are rigorous selection of doctoral students, effective academic supervision, advanced academic training opportunities and interdisciplinary communication as well as administrative support. IMPRS-ESM graduates have been recognized with a variety of awards. 85% of our alumni continue a career in research. In this presentation we review the challenges for an interdisciplinary PhD program in Earth system sciences and the types of routines we have implemented to surmount them as well as key elements that we believe contribute to the success of our doctoral program.

“History, Theory and Ethics of Medicine”: The Last Ten Years. A Survey of Course Content, Methods and Structural Preconditions at Twenty-nine German Medical Faculties

PubMed Central

Schildmann, Jan; Bruns, Florian; Hess, Volker; Vollmann, Jochen

2017-01-01

Objective: “History, Theory, Ethics of Medicine” (German: “Geschichte, Theorie, Ethik der Medizin”, abbreviation: GTE) forms part of the obligatory curriculum for medical students in Germany since the winter semester 2003/2004. This paper presents the results of a national survey on the contents, methods and framework of GTE teaching. Methods: Semi-structured questionnaire dispatched in July 2014 to 38 institutions responsible for GTE teaching. Descriptive analysis of quantitative data and content analysis of free-text answers. Results: It was possible to collect data from 29 institutes responsible for GTE teaching (response: 76%). There is at least one professorial chair for GTE in 19 faculties; two professorial chairs or professorships remained vacant at the time of the survey. The number of students taught per academic year ranges from <100 to >350. Teaching in GTE comprises an average of 2.18 hours per week per semester (min: 1, max: 6). Teaching in GTE is proportionally distributed according to an arithmetic average as follows: history: 35.4%, theory 14.7% and ethics 49.9%. Written learning objectives were formulated for GTE in 24 faculties. The preferred themes of teaching in history, theory or ethics which according to respondents should be taught comprise a broad spectrum and vary. Teaching in ethics (79 from a max. of 81 possible points) is, when compared to history (61/81) and theory (53/81), attributed the most significance for the training of medical doctors. Conclusion: 10 years after the introduction of GTE the number of students and the personnel resources available at the institutions vary considerably. In light of the differences regarding the content elicited in this study the pros and cons of heterogeneity in GTE should be discussed. PMID:28584871

"History, Theory and Ethics of Medicine": The Last Ten Years. A Survey of Course Content, Methods and Structural Preconditions at Twenty-nine German Medical Faculties.

PubMed

Schildmann, Jan; Bruns, Florian; Hess, Volker; Vollmann, Jochen

2017-01-01

Objective: "History, Theory, Ethics of Medicine" (German: "Geschichte, Theorie, Ethik der Medizin", abbreviation: GTE) forms part of the obligatory curriculum for medical students in Germany since the winter semester 2003/2004. This paper presents the results of a national survey on the contents, methods and framework of GTE teaching. Methods: Semi-structured questionnaire dispatched in July 2014 to 38 institutions responsible for GTE teaching. Descriptive analysis of quantitative data and content analysis of free-text answers. Results: It was possible to collect data from 29 institutes responsible for GTE teaching (response: 76%). There is at least one professorial chair for GTE in 19 faculties; two professorial chairs or professorships remained vacant at the time of the survey. The number of students taught per academic year ranges from <100 to >350. Teaching in GTE comprises an average of 2.18 hours per week per semester (min: 1, max: 6). Teaching in GTE is proportionally distributed according to an arithmetic average as follows: history: 35.4%, theory 14.7% and ethics 49.9%. Written learning objectives were formulated for GTE in 24 faculties. The preferred themes of teaching in history, theory or ethics which according to respondents should be taught comprise a broad spectrum and vary. Teaching in ethics (79 from a max. of 81 possible points) is, when compared to history (61/81) and theory (53/81), attributed the most significance for the training of medical doctors. Conclusion: 10 years after the introduction of GTE the number of students and the personnel resources available at the institutions vary considerably. In light of the differences regarding the content elicited in this study the pros and cons of heterogeneity in GTE should be discussed.

Crystal Structure of the Minimalist Max-E47 Protein Chimera

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ahmadpour, Faraz; Ghirlando, Rodolfo; De Jong, Antonia T.

Max-E47 is a protein chimera generated from the fusion of the DNA-binding basic region of Max and the dimerization region of E47, both members of the basic region/helix-loop-helix (bHLH) superfamily of transcription factors. Like native Max, Max-E47 binds with high affinity and specificity to the E-box site, 5'-CACGTG, both in vivo and in vitro. We have determined the crystal structure of Max-E47 at 1.7 Å resolution, and found that it associates to form a well-structured dimer even in the absence of its cognate DNA. Analytical ultracentrifugation confirms that Max-E47 is dimeric even at low micromolar concentrations, indicating that the Max-E47more » dimer is stable in the absence of DNA. Circular dichroism analysis demonstrates that both non-specific DNA and the E-box site induce similar levels of helical secondary structure in Max-E47. These results suggest that Max-E47 may bind to the E-box following the two-step mechanism proposed for other bHLH proteins. In this mechanism, a rapid step where protein binds to DNA without sequence specificity is followed by a slow step where specific protein:DNA interactions are fine-tuned, leading to sequence-specific recognition. Collectively, these results show that the designed Max-E47 protein chimera behaves both structurally and functionally like its native counterparts.« less

Ballistic Evaluation of 7085 Aluminum

DTIC Science & Technology

2012-03-01

direct-fire threats and a lower strength, higher ductility variant, 7085-T7E02, for underbody blast protection kits. Ballistic evaluation was...direct-fire threats and a lower strength, higher ductility variant, 7085-T7E02, for underbody blast protection kits. The U.S. Army Research Laboratory...0.40 max 0.25 max a 0.10 max 0.12 max Titanium 0.06 max 0.10 max 0.15 max 0.02–0.10 0.15 max 0.10 max Zinc 7.0–8.0 3.50–4.50 0.25 max 0.10 max 0.25

Phoenix Lowered into Thermal Vacuum Chamber

NASA Technical Reports Server (NTRS)

2007-01-01

NASA's Phoenix Mars Lander was lowered into a thermal vacuum chamber at Lockheed Martin Space Systems, Denver, in December 2006.

The spacecraft was folded in its aeroshell and underwent environmental testing that simulated the extreme conditions the spacecraft will see during its nine-and-a-half-month cruse to Mars.

The Phoenix mission is led by Principal Investigator Peter H. Smith of the University of Arizona, Tucson, with project management at NASA's Jet Propulsion Laboratory and development partnership with Lockheed Martin Space Systems. International contributions for Phoenix are provided by the Canadian Space Agency, the University of Neuchatel (Switzerland), the University of Copenhagen, and the Max Planck Institute in Germany. JPL is a division of the California Institute of Technology in Pasadena.

X-Shaped Bulge in the Milky Way

NASA Image and Video Library

2016-07-19

In 2010, NASA's Wide-field Infrared Survey Explorer (WISE) mission observed the entire sky twice. Astronomers used these data to point out the X-shaped structure in the bulge of the Milky Way, contained in the small circle at center, as well as the inset image. The circled central portion covers roughly the area of sky that would be blocked by a basketball when held out at arm's length. Dustin Lang, an astronomer at the Dunlap Institute of the University of Toronto, used these data to make this map, which shows the full 360-degree panorama of the sky as seen by WISE. Lang collaborated with Melissa Ness, postdoctoral researcher at the Max Planck Institute for Astronomy in Germany, http://photojournal.jpl.nasa.gov/catalog/PIA20699

Walter Max Dale (formerly Deutsch) (1894-1969): pioneer and eminent radiobiochemist at the Christie Hospital and Holt Radium Institute, Manchester.

PubMed

Shreeve, David R

2010-05-01

The political upheaval in Germany in 1933 and subsequent movement of medical scholars with the support of the Rockefeller Foundation allowed Manchester to benefit from the arrival of Dr Walter Deutsch, later known as Dr Walter Dale. His research background enabled him to develop a radiobiochemistry laboratory at the Christie Hospital and Holt Radium Institute where he became a world authority on the effects of X-rays on enzymes and also the protective effect of additional solutes. In 1959 he initiated and then edited the International Journal of Radiation Biology. By the time of his retirement in 1962 the strength of his research resulted in his laboratory being recognized by the Medical Research Council.

The beginnings of psychoanalytic supervision: the crucial role of Max Eitingon.

PubMed

Watkins, C Edward

2013-09-01

Psychoanalytic supervision is moving well into its 2nd century of theory, practice, and (to a limited extent) research. In this paper, I take a look at the pioneering first efforts to define psychoanalytic supervision and its importance to the psychoanalytic education process. Max Eitingon, the "almost forgotten man" of psychoanalysis, looms large in any such consideration. His writings or organizational reports were seemingly the first psychoanalytic published material to address the following supervision issues: rationale, screening, notes, responsibility, supervisee learning/personality issues, and the extent and length of supervision itself. Although Eitingon never wrote formally on supervision, his pioneering work in the area has continued to echo across the decades and can still be seen reflected in contemporary supervision practice. I also recognize the role of Karen Horney-one of the founders of the Berlin Institute and Poliklinik, friend of Eitingon, and active, vital participant in Eitingon's efforts-in contributing to and shaping the beginnings of psychoanalytic education.

Max Weber or Jesus Christ: in whose image?

PubMed

Fitzpatrick, A M; Gaylor, C C

1985-10-01

The bureaucratic model of organization and the model that emerges from the Gospel and Vatican Council II provide a stark contrast for Catholic health care administrators to ponder. As articulated by sociologist Max Weber, a bureaucracy is based on a hierarchical structure with sharply defined and protected levels of authority, centralized decision making, rules that govern personnel behavior, and an impersonalized view of employees that stresses their roles as functionaries. The Christian, Gospel-based model, on the other hand, places a premium on collegiality, shared authority, the mediation of conscience, the common good, and the work of the individual. Even though only a few will shape management policy in a large hospital, policymaking should be viewed as a service, a ministry that entails stewardship. Catholic health care leaders should reflect the spirit of collegiality by bringing various strata of staff together in a dynamic, united effort. Thus the institution's statement of mission will not be an abstract recitation of pieties but a living reality, a philosophy that is "owned" by the workers.

Characterization of the first true coaxial 18-fold segmented n-type prototype HPGe detector for the GERDA project

NASA Astrophysics Data System (ADS)

Abt, I.; Caldwell, A.; Gutknecht, D.; Kröninger, K.; Lampert, M.; Liu, X.; Majorovits, B.; Quirion, D.; Stelzer, F.; Wendling, P.

2007-07-01

The first true coaxial 18-fold segmented n-type HPGe prototype detector produced by Canberra-France for the GERDA neutrinoless double beta-decay project was tested both at Canberra-France and at the Max-Planck-Institut für Physik in Munich. The main characteristics of the detector are given and measurements concerning detector properties are described. A novel method to establish contacts between the crystal and a Kapton cable is presented.

Low-cost enclosure for the sub-millimeter telescope

NASA Astrophysics Data System (ADS)

Ulich, B. L.; Hoffmann, W. F.; Davison, W. B.; Baars, J. W. M.; Mezger, P. G.

1984-01-01

The University of Arizona and the Max-Planck-Institut fuer Radioastronomie are collaborating to construct a submillimeter-wavelength radio telescope facility at the summit of Mt. Lemmon (2791 m above sea level) near Tucson, Arizona. A corotating building has been designed to protect the 10 m-diameter Submillimeter Telescope against storm damage, to provide large instrumentation rooms at the Nasmyth foci, and to minimize degradation of the reflector profile accuracy and pointing errors caused by wind forces and solar radiation.

Low-Cost Enclosure For The Sub-Millimeter Telescope

NASA Astrophysics Data System (ADS)

Ulich, Bobby L.; Hoffmann, William F.; Davison, Warren B.; Baars, Jacob W. M.; Mezger, Peter G.

1983-11-01

The University of Arizona and the Max-Planck-Institut fur Radioastronomie are collaborating to construct a sub-millimeter wavelength radio telescope facility at the summit of Mt. Lemmon (2791 m above sea level) near Tucson, Arizona. We have designed a corotating building to protect the 10 m diameter Sub-Millimeter Telescope (SMT) against storm damage, to provide large instrumentation rooms at the Nasmyth foci, and to minimize degradation of the reflector profile accuracy and pointing errors caused by wind forces and solar radiation.

Theory and modeling group

NASA Technical Reports Server (NTRS)

Holman, Gordon D.

1989-01-01

The primary purpose of the Theory and Modeling Group meeting was to identify scientists engaged or interested in theoretical work pertinent to the Max '91 program, and to encourage theorists to pursue modeling which is directly relevant to data which can be expected to result from the program. A list of participants and their institutions is presented. Two solar flare paradigms were discussed during the meeting -- the importance of magnetic reconnection in flares and the applicability of numerical simulation results to solar flare studies.

Payload specialist Merbold performing experiment in Spacelab

NASA Image and Video Library

1983-11-28

STS009-13-699 (28 Nov - 8 Dec 1983) --? Ulf Merbold, Spacelab 1 payload specialist, carries out one of the experiments using the gradient heating facility on the materials science double rack facility in the busy science module aboard the Earth-orbiting Space Shuttle Columbia. Representing the European Space Agency, Dr. Merbold comes from Max-Planck Institute in Stuttgart, the Federal Republic of Germany. He is a specialist in crystal lattice defects and low temperature physics. The photograph was made with a 35mm camera.

The solar abundance of Oxygen

NASA Astrophysics Data System (ADS)

Grevesse, N.

2009-07-01

With Martin Asplund (Max Planck Institute of Astrophysics, Garching) and Jacques Sauval (Observatoire Royal de Belgique, Brussels) I recently published detailed reviews on the solar chemical composition ({Asplund et al. 2005}, {Grevesse et al. 2007}). A new one, with Pat Scott (Stockholm University) as additional co-author, will appear in Annual Review of Astronomy and Astrophysics ({Asplund et al. 2009}). Here we briefly analyze recent works on the solar abundance of Oxygen and recommend a value of 8.70 in the usual astronomical scale.

Investigation of the 3D distribution of tropospheric formaldehyde (HCHO) at the city of Mainz (Germany) using measurements of a 4 azimuth MAX-DOAS instrument

NASA Astrophysics Data System (ADS)

Donner, Sebastian; Gu, Myojeong; Remmers, Julia; Wang, Yang; Wagner, Thomas

2017-04-01

The Differential Optical Absorption Spectroscopy (DOAS)-method allows to investigate the distribution of different atmospheric trace gases (e.g. NO2, SO2, HCHO...) simultaneously. This is done by analysing the absorptions of these species in spectra of scattered sunlight. Multi-AXis (MAX)-DOAS measurements observe scattered sun light under different elevation angles. From such measurements tropospheric vertical column densities (VCDs) and vertical profiles of the measured trace gases and aerosols can be determined. We performed measurements using a 4 azimuth MAX-DOAS system on the roof of the Max Planck Institute for Chemistry in Mainz/Germany since 2013. This instrument observes scattered sunlight in 4 separate orthogonal azimuth directions. We derive vertical profiles of trace gases in these 4 different azimuth directions. From these results we can investigate the 3D distribution of the trace gases. Mainz is located at the edge of the Rhine-Main area which is one of the densest populated areas in Germany. Therefore it experiences episodes of high and low pollution depending on the meteorological conditions. In this study we focus on formaldehyde (HCHO). It is either emitted directly by industries and other anthropogenic and biogenic activities. Usually higher amounts are produced by photochemical reactions from precursor substances (secondary production), where it plays an important role in photochemical smog chemistry and O3 chemistry. As it is an intermediate product of basic oxidation cycles of other hydrocarbons (also referred to as volatile organic compounds (VOCs)) especially in summer its concentrations are determined by the abundances of VOCs. Therefore HCHO observations can be used as an indicator for VOCs. Up to now we have nearly 4 years (starting from May 2013) of almost continuous data which provides already a quite large dataset. In this work we present a first overview of our HCHO results including time series of HCHO columns, a first comparison of the results for different azimuth directions, a first characterisation of the corresponding spatial gradients and a comparison to mobile MAX-DOAS measurements which were performed in Winter 2015/2016.

MAX-DOAS NO2 observations over Guangzhou, China; ground-based and satellite comparisons

NASA Astrophysics Data System (ADS)

Drosoglou, Theano; Elissavet Koukouli, Maria; Kouremeti, Natalia; Bais, Alkiviadis F.; Zyrichidou, Irene; Balis, Dimitris; van der A, Ronald J.; Xu, Jin; Li, Ang

2018-04-01

In this study, the tropospheric NO2 vertical column density (VCD) over an urban site in Guangzhou megacity in China is investigated by means of MAX-DOAS measurements during a campaign from late March 2015 to mid-March 2016. A MAX-DOAS system was deployed at the Guangzhou Institute of Geochemistry of the Chinese Academy of Sciences and operated there for about 1 year, during the spring and summer months. The tropospheric NO2 VCDs retrieved by the MAX-DOAS are presented and compared with space-borne observations from GOME-2/MetOp-A, GOME-2/MetOp-B and OMI/Aura satellite sensors. The comparisons reveal good agreement between satellite and MAX-DOAS observations over Guangzhou, with correlation coefficients ranging between 0.795 for GOME-2B and 0.996 for OMI. However, the tropospheric NO2 loadings are underestimated by the satellite sensors on average by 25.1, 10.3 and 5.7 %, respectively, for OMI, GOME-2A and GOME-2B. Our results indicate that GOME-2B retrievals are closer to those of the MAX-DOAS instrument due to the lower tropospheric NO2 concentrations during the days with valid GOME-2B observations. In addition, the effect of the main coincidence criteria is investigated, namely the cloud fraction (CF), the distance (d) between the satellite pixel center and the ground-based measurement site, as well as the time period within which the MAX-DOAS data are averaged around the satellite overpass time. The effect of CF and time window criteria is more profound on the selection of OMI overpass data, probably due to its smaller pixel size. The available data pairs are reduced to half and about one-third for CF ≤ 0.3 and CF ≤ 0.2, respectively, while, compared to larger CF thresholds, the correlation coefficient is improved to 0.996 from about 0.86, the slope value is very close to unity ( ˜ 0.98) and the mean satellite underestimation is reduced to about half (from ˜ 7 to ˜ 3.5 × 1015 molecules cm-2). On the other hand, the distance criterion affects mostly GOME-2B data selection, because GOME-2B pixels are quite evenly distributed among the different radii used in the sensitivity test. More specifically, the number of collocations is notably reduced when stricter radius limits are applied, the r value is improved from 0.795 (d ≤ 50 km) to 0.953 (d ≤ 20 km), and the absolute mean bias decreases about 6 times for d ≤ 30 km compared to the reference case (d ≤ 50 km).

7. VIEW OF INTERIOR OF BUILDING 220 FIRST FLOOR, DENTAL ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. VIEW OF INTERIOR OF BUILDING 220 FIRST FLOOR, DENTAL FACILITY AREA (ORIGINALLY THE ARSENAL ROOM). THE ORIGINAL DOOR, SHOWN ON THE LEFT OF PHOTO, IS CONSTRUCTED OF 2' THICK HARDWOOD SANDWICHED BY 1/4' THICK STEEL PLATES WHICH ARE BOLTED TOGETHER. THE DOOR SHOWN ON THE RIGHT OF PHOTO, WAS ADDED DURING THE RENOVATION INTO A DENTAL FACILITY. THE TEXTURED WALLS DISPLAY THE IMPRESSION OF THE WOOD FORMS (5' WIDE PLANKS) USED TO CAST THE 12' THICK CONCRETE WALLS. - U.S. Naval Base, Pearl Harbor, Brig, Neville Way near Ninth Street at Marine Barracks, Pearl City, Honolulu County, HI

Ecological Sustainability: What Role for Public Health Education?

PubMed Central

Fleming, Mary Louise; Tenkate, Thomas; Gould, Trish

2009-01-01

This article explores the notion of ecological sustainability in the context of public health education and the contribution Universities can make in creating environments that include ecologically sustainable practices. It considers the important role of environmental health in building a sustainable future for the population as a central plank of public health. It presents the evidence for the need for comprehensive approaches to ecological sustainability within the University and offers suggestions about how this can take place. It concludes by arguing that to date there is a substantial gap between the rhetoric and the reality in the University context. PMID:19742169

U.S. Navy Wire-Rope Handbook. Volume 1. Design and Engineering of Wire-Rope Systems

DTIC Science & Technology

1976-01-01

by " braiding " or "weaving" one rope end into another. Splices may be made at the end of a single rope after forming a loop (an eye splice) or between...rags, large pieces of old hemp rope and fire hose are other popular types of chafing gear for semi-fixed position ropes (see Figure 7-3(b)). 7.4. LINKS...Figure 7-3. Chafing Gear 7-6 Links 7.4. SWOOD PLANK FIRE HOSE ., ’ _APPLY GREASE CANJVAS, LEATHER, COPPER (b) For Semi-Fixed Position Ropes lo- Figcre

Prototypical Concepts and Misconceptions of Plate Tectonic Boundaries

NASA Astrophysics Data System (ADS)

Sibley, D. F.; Patino, L. C.

2003-12-01

Students of geology encounter many prototypical/exemplar concepts* that include representative, but not necessarily defining, features and characteristics. This study of students' prototypical representations of plate tectonic boundaries indicates that their representations are rich sources of information about their misconceptions about plate tectonics. After lectures in plate tectonics and mountain building, 353 students in a general education geology class were asked to draw a continent-continent convergent boundary. For this study, a correct answer is defined as having the major features in correct proportions as depicted in the plate boundary diagrams on the USGS web. Fifty-two percent of the drawings were either incorrect or incomplete such that they could not be interpreted. Only 48% were readily interpretable, and of these 22% drew the boundary correctly, showing a thickening of crust where two continents collide. Thirty-three percent drew the boundary showing concave slabs of continental crust as one might imagine two pieces of firm rubber pushed together on a rigid surface and 45% depicted mountains as one might imagine inverted ice cream cones on a rigid plank. Twenty-one senior class geology majors and graduate students were given the same assignment. Forty-eight percent rendered a correct drawing, whereas 38% drew the same ice cream cone on a plank type picture that 45% of the general education students drew. In a second class of 12 geology majors, only 1 student drew a cross section of a continent-ocean boundary similar to standard representation. Four of 12 drew mountains on the top of continental crust over a subduction zone but did not draw a compensating mass within the crust or lithosphere. Prototypical drawings provide more information about students' concepts than do most multiple-choice questions. For example, sixty-two percent of theses students who drew mountains similar to foam rubber pads pushed together on a desk or ice cream cones on a plank correctly answered a multiple-choice question that would appear to indicate a better understanding than the drawings reveal. Furthermore, 12 interviewed students made statements that could be interpreted to indicate that they understood the concept of mountain building at plate tectonic boundaries better than their drawings suggest. Incoherence of multiple-choice responses, verbal statements and drawings may be common in novice learners. If cognitive scientists are correct in their model of multiple types of mental representations for the same term, then the fact that novices may hold inconsistent representations is not surprising. The fact that students at various academic levels draw very similar prototypes that are incorrect is evidence that students have distinct and persistent prototype misconceptions. * Cognitive scientists define a prototypical/exemplar concept as a mental representation of the best examples or central tendencies of a term.

Maximal heart rate in soccer players: measured versus age-predicted.

PubMed

Nikolaidis, Pantelis T

2015-01-01

Although maximal heart rate (HR max) is widely used to assess exercise intensity in sport training, and particularly in soccer, there are limited data with regards to the use of age-based prediction equations of HR max in soccer players. The aim of this study was to compare the measured-HR max with two prediction equations (Fox-HR max = 220 - age and Tanaka-HR max = 208 - 0.7 × age) in soccer players. Adolescent (n = 162, 15.8 ± 1.5 years) and adult players (n = 158, 23.4 ± 4.6 years), all members of competitive clubs, voluntarily performed a graded exercise field test (Conconi protocol) to assess HR max . The measured-HR max (197.6 ± 9.4 bpm in total, 200.2 ± 7.9 bpm in adolescent players, and 195.0 ± 10.0 bpm in adult players) was explained by the formula HR max = 212.3 - 0.75 × age (r = -0.41, standard error of the estimate = 8.6). In the total sample, Fox-HR max overestimated measured-HR max [mean difference (95% confidence intervals) = 2.8 bpm (1.6; 3.9)], while Tanaka-HR max underestimated HR max [-3.3 bpm (-4.5; -2.2)]. In adolescents, Fox-HR max overestimated measured-HR max [4.0 bpm (2.5; 5.5)] and Tanaka-HR max underestimated HR max [- 3.2 bpm (-4.7; -1.8)]. In adults, Tanaka-HR max underestimated HR max [-5.0 bpm (-5.3; -4.7)], while there was not any difference between Fox-HR max and measured-HR max [1.6 bpm (-3.4; 0.2)]. The results of this study failed to validate two widely used prediction equations in a large sample of soccer players, indicating the need for a sport-specific equation. On the other hand, the new equation that we presented should be investigated further by future studies before being adopted by coaches and fitness trainers.

Influence of acute moderate hypoxia on time to exhaustion at vVO2max in unacclimatized runners.

PubMed

Billat, V L; Lepretre, P M; Heubert, R P; Koralsztein, J P; Gazeau, F P

2003-01-01

Eight unacclimatized long-distance runners performed, on a level treadmill, an incremental test to determine the maximal oxygen uptake (VO2max) and the minimal velocity eliciting VO2max (vVO2max) in normoxia (N) and acute moderate hypoxia (H) corresponding to an altitude of 2,400 m (PIO 2 of 109 mmHg). Afterwards, on separate days, they performed two all-out constant velocity runs at vO2 max in a random order (one in N and the other in H). The decrease in VO2max between N and H showed a great degree of variability amongst subjects as VO2max decreased by 8.9 +/- 4 ml x min(-1) x kg)(-1) in H vs. N conditions (-15.3 +/- 6.3 % with a range from -7.9 % to -23.8 %). This decrease in VO2max was proportional to the value of VO2max (VO2max vs. delta VO2max N-H, r = 0.75, p = 0.03). The time run at vVO2max was not affected by hypoxia (483 +/- 122 vs. 506 +/- 148 s, in N and H, respectively, p = 0.37). However, the greater the decrease in vVO2max during hypoxia, the greater the runners increased their time to exhaustion at vVO2max (vVO2max N-H vs. tlim @vVO2max N-H, r = -0.75, p = 0.03). In conclusion, this study showed that there was a positive association between the extent of decrease in vVO2max, and the increase in run time at vVO2max in hypoxia.

QTL mapping of stalk bending strength in a recombinant inbred line maize population.

PubMed

Hu, Haixiao; Liu, Wenxin; Fu, Zhiyi; Homann, Linda; Technow, Frank; Wang, Hongwu; Song, Chengliang; Li, Shitu; Melchinger, Albrecht E; Chen, Shaojiang

2013-09-01

Stalk bending strength (SBS) is a reliable indicator for evaluating stalk lodging resistance of maize plants. Based on biomechanical considerations, the maximum load exerted to breaking (F max), the breaking moment (M max) and critical stress (σ max) are three important parameters to characterize SBS. We investigated the genetic architecture of SBS by phenotyping F max, M max and σ max of the fourth internode of maize plants in a population of 216 recombinant inbred lines derived from the cross B73 × Ce03005 evaluated in four environments. Heritability of F max, M max and σ max was 0.81, 0.79 and 0.75, respectively. F max and σ max were positively correlated with several other stalk characters. By using a linkage map with 129 SSR markers, we detected two, three and two quantitative trait loci (QTL) explaining 22.4, 26.1 and 17.2 % of the genotypic variance for F max, M max and σ max, respectively. The QTL for F max, M max and σ max located in adjacent bins 5.02 and 5.03 as well as in bin 10.04 for F max were detected with high frequencies in cross-validation. As our QTL mapping results suggested a complex polygenic inheritance for SBS-related traits, we also evaluated the prediction accuracy of two genomic prediction methods (GBLUP and BayesB). In general, we found that both explained considerably higher proportions of the genetic variance than the values obtained in QTL mapping with cross-validation. Nevertheless, the identified QTL regions could be used as a starting point for fine mapping and gene cloning.

Regulation of drought tolerance by the F-box protein MAX2 in Arabidopsis.

PubMed

Bu, Qingyun; Lv, Tianxiao; Shen, Hui; Luong, Phi; Wang, Jimmy; Wang, Zhenyu; Huang, Zhigang; Xiao, Langtao; Engineer, Cawas; Kim, Tae Houn; Schroeder, Julian I; Huq, Enamul

2014-01-01

MAX2 (for MORE AXILLARY GROWTH2) has been shown to regulate diverse biological processes, including plant architecture, photomorphogenesis, senescence, and karrikin signaling. Although karrikin is a smoke-derived abiotic signal, a role for MAX2 in abiotic stress response pathways is least investigated. Here, we show that the max2 mutant is strongly hypersensitive to drought stress compared with wild-type Arabidopsis (Arabidopsis thaliana). Stomatal closure of max2 was less sensitive to abscisic acid (ABA) than that of the wild type. Cuticle thickness of max2 was significantly thinner than that of the wild type. Both of these phenotypes of max2 mutant plants correlate with the increased water loss and drought-sensitive phenotype. Quantitative real-time reverse transcription-polymerase chain reaction analyses showed that the expression of stress-responsive genes and ABA biosynthesis, catabolism, transport, and signaling genes was impaired in max2 compared with wild-type seedlings in response to drought stress. Double mutant analysis of max2 with the ABA-insensitive mutants abi3 and abi5 indicated that MAX2 may function upstream of these genes. The expression of ABA-regulated genes was enhanced in imbibed max2 seeds. In addition, max2 mutant seedlings were hypersensitive to ABA and osmotic stress, including NaCl, mannitol, and glucose. Interestingly, ABA, osmotic stress, and drought-sensitive phenotypes were restricted to max2, and the strigolactone biosynthetic pathway mutants max1, max3, and max4 did not display any defects in these responses. Taken together, these results uncover an important role for MAX2 in plant responses to abiotic stress conditions.

On the retrieval of significant wave heights from spaceborne Synthetic Aperture Radar using the Max-Planck Institut algorithm.

PubMed

Violante-Carvalho, Nelson

2005-12-01

Synthetic Aperture Radar (SAR) onboard satellites is the only source of directional wave spectra with continuous and global coverage. Millions of SAR Wave Mode (SWM) imagettes have been acquired since the launch in the early 1990's of the first European Remote Sensing Satellite ERS-1 and its successors ERS-2 and ENVISAT, which has opened up many possibilities specially for wave data assimilation purposes. The main aim of data assimilation is to improve the forecasting introducing available observations into the modeling procedures in order to minimize the differences between model estimates and measurements. However there are limitations in the retrieval of the directional spectrum from SAR images due to nonlinearities in the mapping mechanism. The Max-Planck Institut (MPI) scheme, the first proposed and most widely used algorithm to retrieve directional wave spectra from SAR images, is employed to compare significant wave heights retrieved from ERS-1 SAR against buoy measurements and against the WAM wave model. It is shown that for periods shorter than 12 seconds the WAM model performs better than the MPI, despite the fact that the model is used as first guess to the MPI method, that is the retrieval is deteriorating the first guess. For periods longer than 12 seconds, the part of the spectrum that is directly measured by SAR, the performance of the MPI scheme is at least as good as the WAM model.

MIENS Minimum Information about an ENvironmental Sequence and The GSC's Not-for-Profit (GSC8 Meeting)

ScienceCinema

Yilmaz, Pelin; Kolker, Eugene

2018-01-24

The Genomic Standards Consortium was formed in September 2005. It is an international, open-membership working body which promotes standardization in the description of genomes and the exchange and integration of genomic data. The 2009 meeting was an activity of a five-year funding Research Coordination Network from the National Science Foundation and was held at the DOE Joint Genome Institute with organizational support provided by the JGI and by the University of California - San Diego. Pelin Yilmaz of the Max Planck Institute-Bremen talks about the MIENS specification and Eugene Kolker of Seattle Children's Hospital discusses the GSC's non-for-profit at the Genomic Standards Consortium's 8th meeting at the DOE JGI in Walnut Creek, CA on Sept. 9, 2009.

Team Huddle Before Lifting Phoenix into Test Chamber

NASA Technical Reports Server (NTRS)

2007-01-01

Spacecraft specialists huddle to discuss the critical lift of NASA's Phoenix Mars Lander into a thermal vacuum chamber.

In December 2006, the spacecraft was in a cruise configuration prior to going into environmental testing at a Lockheed Martin Space Systems facility near Denver. At all stages of assembly and testing, the spacecraft is handled with extreme care and refinement.

The Phoenix mission is led by Principal Investigator Peter H. Smith of the University of Arizona, Tucson, with project management at NASA's Jet Propulsion Laboratory and development partnership with Lockheed Martin Space Systems. International contributions for Phoenix are provided by the Canadian Space Agency, the University of Neuchatel (Switzerland), the University of Copenhagen, and the Max Planck Institute in Germany. JPL is a division of the California Institute of Technology in Pasadena.

78 FR 78515 - Removal of JADE Act Tags

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-26

... pursuant to IEEPA: 1. GOLDEN AARON PTE. LTD. 2. MAX MYANMAR GROUP OF COMPANIES 3. DAGON INTERNATIONAL... AVENIR EXECUTIVE SERVICED APARTMENT 9. MAX (MYANMAR) CONSTRUCTION CO. LTD. 10. MAX MYANMAR GEMS AND JEWELLERY CO. LTD. 11. MAX MYANMAR MANUFACTURING CO. LTD. 12. MAX MYANMAR SERVICES CO. LTD. 13. MAX MYANMAR...

Regulation of Drought Tolerance by the F-Box Protein MAX2 in Arabidopsis1[C][W][OPEN

PubMed Central

Bu, Qingyun; Lv, Tianxiao; Shen, Hui; Luong, Phi; Wang, Jimmy; Wang, Zhenyu; Huang, Zhigang; Xiao, Langtao; Engineer, Cawas; Kim, Tae Houn; Schroeder, Julian I.; Huq, Enamul

2014-01-01

MAX2 (for MORE AXILLARY GROWTH2) has been shown to regulate diverse biological processes, including plant architecture, photomorphogenesis, senescence, and karrikin signaling. Although karrikin is a smoke-derived abiotic signal, a role for MAX2 in abiotic stress response pathways is least investigated. Here, we show that the max2 mutant is strongly hypersensitive to drought stress compared with wild-type Arabidopsis (Arabidopsis thaliana). Stomatal closure of max2 was less sensitive to abscisic acid (ABA) than that of the wild type. Cuticle thickness of max2 was significantly thinner than that of the wild type. Both of these phenotypes of max2 mutant plants correlate with the increased water loss and drought-sensitive phenotype. Quantitative real-time reverse transcription-polymerase chain reaction analyses showed that the expression of stress-responsive genes and ABA biosynthesis, catabolism, transport, and signaling genes was impaired in max2 compared with wild-type seedlings in response to drought stress. Double mutant analysis of max2 with the ABA-insensitive mutants abi3 and abi5 indicated that MAX2 may function upstream of these genes. The expression of ABA-regulated genes was enhanced in imbibed max2 seeds. In addition, max2 mutant seedlings were hypersensitive to ABA and osmotic stress, including NaCl, mannitol, and glucose. Interestingly, ABA, osmotic stress, and drought-sensitive phenotypes were restricted to max2, and the strigolactone biosynthetic pathway mutants max1, max3, and max4 did not display any defects in these responses. Taken together, these results uncover an important role for MAX2 in plant responses to abiotic stress conditions. PMID:24198318

Max-E47, a Designed Minimalist Protein that Targets the E-Box DNA Site In Vivo and In Vitro

PubMed Central

Xu, Jing; Chen, Gang; De Jong, Antonia T.; Shahravan, S. Hesam; Shin, Jumi A.

2009-01-01

Max-E47 is a designed hybrid protein comprising the Max DNA-binding basic region and E47 HLH dimerization subdomain. In the yeast one-hybrid system (Y1H), Max-E47 shows strong transcriptional activation from the E-box site, 5'-CACGTG, targeted by the Myc/Max/Mad network of transcription factors; two mutants, Max-E47Y and Max-E47YF, activate more weakly from the E-box in the Y1H. Quantitative fluorescence anisotropy titrations to gain free energies of protein:DNA binding gave low nM Kd values for the native MaxbHLHZ, Max-E47, and the Y and YF mutants binding to the E-box site (14 nM, 15 nM, 9 nM, and 6 nM, respectively), with no detectable binding to a nonspecific control duplex. Because these minimalist, E-box-binding hybrids have no activation domain and no interactions with the c-MycbHLHZ, as shown by the yeast two-hybrid assay, they can potentially serve as dominant-negative inhibitors that suppress activation of E-box-responsive genes targeted by transcription factors including the c-Myc/Max complex. As proof-of-principle, we used our modified Y1H, which allows direct competition between two proteins vying for a DNA target, to show that Max-E47 effectively outcompetes the native MaxbHLHZ for the E-box; weaker competition is observed from the two mutants, consistent with Y1H results. These hybrids provide a minimalist scaffold for further exploration of the relationship between protein structure and DNA-binding function and may have applications as protein therapeutics or biochemical probes capable of targeting the E-box site. PMID:19449889

The Expression of Petunia Strigolactone Pathway Genes is Altered as Part of the Endogenous Developmental Program

PubMed Central

Drummond, Revel S. M.; Sheehan, Hester; Simons, Joanne L.; Martínez-Sánchez, N. Marcela; Turner, Rebecca M.; Putterill, Joanna; Snowden, Kimberley C.

2012-01-01

Analysis of mutants with increased branching has revealed the strigolactone synthesis/perception pathway which regulates branching in plants. However, whether variation in this well conserved developmental signaling system contributes to the unique plant architectures of different species is yet to be determined. We examined petunia orthologs of the Arabidopsis MAX1 and MAX2 genes to characterize their role in petunia architecture. A single ortholog of MAX1, PhMAX1 which encodes a cytochrome P450, was identified and was able to complement the max1 mutant of Arabidopsis. Petunia has two copies of the MAX2 gene, PhMAX2A and PhMAX2B which encode F-Box proteins. Differences in the transcript levels of these two MAX2-like genes suggest diverging functions. Unlike PhMAX2B, PhMAX2A mRNA levels change in leaves of differing age/position on the plant. Nonetheless, this gene functionally complements the Arabidopsis max2 mutant indicating that the biochemical activity of the PhMAX2A protein is not significantly different from MAX2. The expression of the petunia strigolactone pathway genes (PhCCD7, PhCCD8, PhMAX1, PhMAX2A, and PhMAX2B) was then further investigated throughout the development of wild-type petunia plants. Three of these genes showed changes in mRNA levels over a development series. Alterations to the expression patterns of these genes may influence the branching growth habit of plants by changing strigolactone production and/or sensitivity. These changes could allow both subtle and dramatic changes to branching within and between species. PMID:22645562

Proceedings of the 6th European VLBI Network Symposium

NASA Astrophysics Data System (ADS)

Ros, Eduardo; Porcas, Richard W.; Lobanov, Andrei P.; Zensus, J. Anton

This volume contains the papers presented at the 6th Symposium of the European VLBI Network, held in Bonn on 25-28 June 2002. The initial aim of these biennial gatherings of European VLBI practitioners was to review in a timely manner new results and technical developments related to Very Long Baseline Interferometry. Now, however, interest and participation in the EVN Symposia reaches far beyond Europe, reflecting the fact that scientific research and development programs are carried out to a high degree in international and often truly global collaborations. More than 120 scientists from around the world registered for participation in the Symposium. The Symposium was hosted by the Max-Planck-Institut für Radioastronomie and was held at the Gustav Stresemann Institut. In addition to the scientific sessions and poster presentations, the program included an EVN Users Meeting, an MPIfR versus Rest-of-the-World football match (highly appropriate given the competing World Cup event!), a visit to the MPIfR's 100m radio telescope in Effelsberg, and a Conference Dinner held in the nearby old walled town of Bad Müunstereifel. To maximize the usefulness of these proceedings (and possibly as a daring precedent) the Editors decided to demand the written versions of talks and posters and to complete the editorial work before the meeting, and to deliver the book to the participants at the beginning of the Symposium. We thank the authors for their cooperation in delivering publication-ready electronic manuscripts and for meeting the strict deadlines. It is highly gratifying that only a handful of the 100 presentations are not represented in this volume. The editors have made minor changes to some of the contributions in order to improve readability, and take responsibility for any errors arising from these changes. Besides the authors, many individuals have contributed to the preparation of the meeting and its proceedings. In addition to many members of the MPIfR staff, we especially wish to thank: W. Alef, U. Bach, E. Fürst, E. Fingas, L. Fuhrmann, L. Gurvits, N. Junkes, M. Kadler, A. Kraus, E. Middelberg, P. Müller, B. Naunheim, J. Schmidt, and R. Schwartz. Financial support for the Symposium came from the Max-Planck-Institut für Radioastronomie, from the 5th Framework Programme of the European Commission (IHP - Infrastructure Cooperation Networks, contract number HPRI-CT-1999-400003), and from the Max Planck Research Prize for International Collaboration.

Evaluation of left ventricular function in anesthetized patients using femoral artery dP/dt(max).

PubMed

De Hert, Stefan G; Robert, Dominique; Cromheecke, Stefanie; Michard, Frédéric; Nijs, Jan; Rodrigus, Inez E

2006-06-01

The purpose of this study was to compare dP/dt(max) estimated from a femoral artery pressure tracing to left ventricular (LV) dP/dt(max) during various alterations in myocardial loading and contractile function. Seventy patients scheduled for elective coronary artery bypass surgery. All patients were instrumented with a high-fidelity LV catheter, a pulmonary artery catheter, and a femoral arterial catheter. In 40 patients, hemodynamic measurements were performed before and after passive leg raising and before and after calcium administration (5 mg/kg); and in 30 other patients, hemodynamic measurements were performed before and after dobutamine infusion (5 microg/kg/min over 10 minutes). LV and femoral dP/dt(max) were significantly correlated (r = 0.82, p < 0.001), but femoral dP/dt(max) systematically underestimated LV dP/dt(max) (bias = -361 +/- 96 mmHg/s). Passive leg raising induced significant increases in central venous pressure and LV end-diastolic pressure, but femoral dP/dt(max), stroke volume, and LV dP/dt(max) remained unaltered. Calcium administration induced significant and marked increases in LV dP/dt(max) (23% +/- 9%) and femoral dP/dt(max) (37% +/- 14%) associated with a significant increase in stroke volume (9% +/- 2%). Dobutamine infusion also induced significant and marked increases in LV dP/dt(max) (25% +/- 8%) and femoral dP/dt(max) (35% +/- 12%) associated with a significant increase in stroke volume (14% +/- 3%). Overall, a very close linear relationship (r = 0.93) and a good agreement (bias = -5 +/- 17 mmHg/s) were found between changes in LV dP/dt(max) and changes in femoral dP/dt(max). A very close relationship was also observed between changes in LV dP/dt(max) and changes in femoral dP/dt(max) during each intervention (leg raising, calcium administration, and dobutamine infusion). Femoral dP/dt(max) underestimated LV dP/dt(max), but changes in femoral dP/dt(max) accurately reflected changes in LV dP/dt(max) during various interventions.

Physical Education and Sport: Does Participation Relate to Physical Activity Patterns, Observed Fitness, and Personal Attitudes and Beliefs?

PubMed

Loprinzi, Paul D; Cardinal, Bradley J; Cardinal, Marita K; Corbin, Charles B

2018-03-01

The purpose of this study was to examine the associations between physical education (PE) and sports involvement with physical activity (PA), physical fitness, and beliefs about PA among a national sample of adolescents. Data from the National Health and Nutrition Examination Survey National Youth Fitness Survey were used. A total of 459 adolescents aged 12 to 15 years. Adolescents self-reported engagement in the above parameters; muscular fitness objectively determined. Multivariable linear regression. Adolescents who had PE during school days had a higher enjoyment of participating in PE (β = 0.32; P = .01), engaged in more days of being physically active for ≥60 min/d (β = 1.02; P < .001), and performed the plank fitness test longer (β = 17.2; P = .002). Adolescents who played school sports reported that more PA was needed for good health (β = 0.23; P = .04), had a higher enjoyment of participating in PE (β = 0.31; P = .003), engaged in more days of being physically active for ≥60 min/d (β = 0.70; P = .01), performed more pull-ups (β = 2.33; P = .008), had a stronger grip strength (β = 2.5; P = .01), and performed the plank fitness test longer (β = 11.6; P = .04). Adolescents who had PE during school, who had more frequent and long-lasting PE, and who played school sports generally had more accurate perceptions of the amount of PA needed for good health, had greater enjoyment of PE, were more physically active, and performed better on several muscular fitness-related tests. This underscores the importance of PE integration in the schools and encouragement of school sports participation.

Postural stability effects of random vibration at the feet of construction workers in simulated elevation.

PubMed

Simeonov, P; Hsiao, H; Powers, J; Ammons, D; Kau, T; Amendola, A

2011-07-01

The risk of falls from height on a construction site increases under conditions which degrade workers' postural control. At elevation, workers depend heavily on sensory information from their feet to maintain balance. The study tested two hypotheses: "sensory enhancement"--sub-sensory (undetectable) random mechanical vibrations at the plantar surface of the feet can improve worker's balance at elevation; and "sensory suppression"--supra-sensory (detectable) random mechanical vibrations can have a degrading effect on balance in the same experimental settings. Six young (age 20-35) and six aging (age 45-60) construction workers were tested while standing in standard and semi-tandem postures on instrumented gel insoles. The insoles applied sub- or supra-sensory levels of random mechanical vibrations to the feet. The tests were conducted in a surround-screen virtual reality system, which simulated a narrow plank at elevation on a construction site. Upper body kinematics was assessed with a motion-measurement system. Postural stability effects were evaluated by conventional and statistical mechanics sway measures, as well as trunk angular displacement parameters. Analysis of variance did not confirm the "sensory enhancement" hypothesis, but provided evidence for the "sensory suppression" hypothesis. The supra-sensory vibration had a destabilizing effect, which was considerably stronger in the semi-tandem posture and affected most of the sway variables. Sensory suppression associated with elevated vibration levels on a construction site may increase the danger of losing balance. Construction workers at elevation, e.g., on a beam or narrow plank might be at increased risk of fall if they can detect vibrations under their feet. To reduce the possibility of losing balance, mechanical vibration to supporting structures used as walking/working surfaces should be minimized when performing construction tasks at elevation. Published by Elsevier Ltd.

Clinical Rating of Movement-Pattern Quality in Patients With Femoroacetabular Impingement Syndrome: A Methodological Study.

PubMed

Casartelli, Nicola C; Maffiuletti, Nicola A; Brunner, Romana; Büchi, Marcel; Sutter, Reto; Pfirrmann, Christian W; Naal, Florian D; Leunig, Michael; Bizzini, Mario

2018-04-01

Study Design Cross-sectional study. Objectives To evaluate intrarater and interrater agreement among physical therapists with different clinical experience in performing a visual rating of movement-pattern quality of patients with femoroacetabular impingement (FAI) syndrome using a semi-quantitative scale. Background Visual rating of movement patterns in patients with FAI syndrome is of interest, because poor control of dynamic hip motion is frequently noted. Methods A video camera was used to record the performance of 34 patients with FAI syndrome performing single-limb standing, squat, frontal lunge, hop lunge, bridge, and plank. Visual rating of movement, as recorded on video, was performed by a highly experienced, a moderately experienced, and a novice physical therapist on 2 occasions using a semi-quantitative scale. Hip abductor strength was assessed using dynamometry, and hip pain and function were assessed with a patient-reported questionnaire. Intrarater and interrater agreement among physical therapists was evaluated using Gwet's agreement coefficient 1. Construct validity was evaluated as the association between physical therapists' rating and patients' hip abductor strength, pain, and function. Results Good intrarater and interrater agreement was observed in the highly experienced and moderately experienced physical therapists when rating single-limb standing, bridge, and plank. Poor to moderate intrarater and interrater agreement was found when they rated squat, frontal lunge, and hop lunge. Poor performers, as rated by the highly experienced physical therapist only, demonstrated lower hip abductor strength (P<.05), and similar hip pain and hip function compared to those of good performers. Conclusion Movement-pattern quality of patients with FAI syndrome should be rated by a highly experienced physical therapist. J Orthop Sports Phys Ther 2018;48(4):260-269. doi:10.2519/jospt.2018.7840.

The effects of unstable surface balance training on postural sway, stability, functional ability and flexibility in women.

PubMed

Nepocatych, Svetlana; Ketcham, Caroline J; Vallabhajosula, Srikant; Balilionis, Gytis

2018-01-01

This study examined the effects of balance training routine, using both sides utilized balance trainer (BOSU) and aerobic step (STEP) on postural sway and functional ability in middle-aged women. Twenty-seven females participated in the study, age 40.6±12.0 years, body mass 72.0±14.0 kg, height 164.0±7.7 cm, BMI 26.5±4.5 kg/m2, and relative body fat 33.1±7.4%. Participants were divided into two groups and performed progressive exercise routine on either STEP or BOSU for three weeks. Pre- and post-test consisted of Postural Sway Test performed on the Biodex Balance System, Functional Ability Test, Sit and Reach Test and Plank. A significant time effect was observed for both groups for sway index(P=0.029) and center of pressure antero-posterior (AP) displacement (P=0.038) but not for sway area or medio-lateral (ML) displacement (P>0.05). In addition, BOSU group had significantly lower Sway Index(P=0.048) and ML range (P=0.035) scores when vision and surface was altered compared to STEP group. A significant time effect was observed in walking-up the stairs (P=0.020), sit and reach test (P=0.035), and plank (P<0.001), but not for walking down the stairs. However, no other significant interactions were observed. Programs that incorporate multisensory balance training have a potential to induce adaptive responses in neuromuscular system that enhances postural control, balance and functional ability of women. The training using BOSU may help improve static balance and functional ability in women.

Effect of a core conditioning intervention on tests of trunk muscular endurance in school-aged children.

PubMed

Allen, Brett A; Hannon, James C; Burns, Ryan D; Williams, Skip M

2014-07-01

Trunk and core muscular development has been advocated to increase athletic performance and for maintenance of musculoskeletal health, especially related to the prevention of low back pain (LBP). The purpose of this study was to examine the effects of a simple core conditioning routine on tests of trunk and core muscular endurance in school-aged children. Participants included 164 students (86 girls, 78 boys; mean age, 11.5 ± 2.5 years) recruited from a grade school in a metropolitan area located in the southwestern United States. Students performed an equipment-free, moderate-to-high intensity, dynamic core conditioning warm-up routine once a week for a period of 6 weeks during the start of their physical education classes. The intervention consisted of 10 different dynamic core conditioning exercises performed at a 30-second duration per exercise totaling 5 minutes per session. Pre- and post-assessments of muscular endurance consisted of 5 different trunk and core muscular endurance tests: Parallel Roman Chair Dynamic Back Extension, Prone Plank, Lateral Plank, Dynamic Curl-Up, and Static Curl-up. A generalized estimation equation was used to analyze differences in pre- and post-intervention muscular fitness assessments controlling for gender and grade level. Analysis of the data revealed significant increases in muscular fitness test performance for each of the 5 measured outcomes (p < 0.001). Because risk factors of LBP are thought to commence during childhood, results of this study suggest that it may be desirable for children and adolescents to perform moderate-to-high intensity dynamic core exercises during physical education warm-up to improve trunk and core muscular endurance.

Physical Performance Measures of Flexibility, Hip Strength, Lower Limb Power and Trunk Endurance in Healthy Navy Cadets: Normative Data and Differences Between Sex and Limb Dominance.

PubMed

Lopes, Thiago Jambo Alves; Simic, Milena; Alves, Daniel de Souza; Bunn, Priscila Dos Santos; Rodrigues, Allan Inoue; Terra, Bruno de Souza; Lima, Maicom da Silva; Ribeiro, Fabrício Miranda; Vilão, Patrick; Pappas, Evangelos

2018-01-17

The objectives were to provide normative data on commonly used physical performance tests that may be associated with musculoskeletal injuries in Navy cadets, and assess for sex and limb dominance differences. A large cohort of Navy cadets were assessed for physical performance tests of flexibility (ankle dorsiflexion range of motion and sit and reach), isometric hip strength, lower limb power (single leg hop), and trunk endurance (plank and side plank tests). Besides providing normative data tables, sex and limb dominance differences were assessed by a two-way mixed ANOVA. A total of 545 Brazilian Navy cadets (394 males) representing 79% of the cadets in the Academy participated. Normative reference values were reported as mean±SD, 95%CI and percentiles. For tests of muscle strength, power and endurance, males performed better than females (p<0.001). For flexibility tests, females achieved greater distances than males for the sit and reach test (p<0.001), but no difference for ankle dorsiflexion (p=0.51). Overall, there were no clinically relevant differences between limbs. In conclusion, normative data for commonly used physical performance tests were provided. Although no clinically relevant side-to-side differences were found, males presented higher values for lower limb strength and power, as well as trunk endurance than females, while females demonstrated increased flexibility. Valuable normative data are provided to professionals who work with young, active populations from the injury prevention or rehabilitation perspective; as the current study may help professionals to identify athletes or cadets whose performance is outside the normative values and may be at risk for injury.

The prone bridge test: Performance, validity, and reliability among older and younger adults.

PubMed

Bohannon, Richard W; Steffl, Michal; Glenney, Susan S; Green, Michelle; Cashwell, Leah; Prajerova, Kveta; Bunn, Jennifer

2018-04-01

The prone bridge maneuver, or plank, has been viewed as a potential alternative to curl-ups for assessing trunk muscle performance. The purpose of this study was to assess prone bridge test performance, validity, and reliability among younger and older adults. Sixty younger (20-35 years old) and 60 older (60-79 years old) participants completed this study. Groups were evenly divided by sex. Participants completed surveys regarding physical activity and abdominal exercise participation. Height, weight, body mass index (BMI), and waist circumference were measured. On two occasions, 5-9 days apart, participants held a prone bridge until volitional exhaustion or until repeated technique failure. Validity was examined using data from the first session: convergent validity by calculating correlations between survey responses, anthropometrics, and prone bridge time, known groups validity by using an ANOVA comparing bridge times of younger and older adults and of men and women. Test-retest reliability was examined by using a paired t-test to compare prone bridge times for Session1 and Session 2. Furthermore, an intraclass correlation coefficient (ICC) was used to characterize relative reliability and minimal detectable change (MDC 95% ) was used to describe absolute reliability. The mean prone bridge time was 145.3 ± 71.5 s, and was positively correlated with physical activity participation (p ≤ 0.001) and negatively correlated with BMI and waist circumference (p ≤ 0.003). Younger participants had significantly longer plank times than older participants (p = 0.003). The ICC between testing sessions was 0.915. The prone bridge test is a valid and reliable measure for evaluating abdominal performance in both younger and older adults. Copyright © 2017 Elsevier Ltd. All rights reserved.

The Effect of Commonly Performed Exercises on the Levator Hiatus Area and the Length and Strength of Pelvic Floor Muscles in Postpartum Women.

PubMed

Siff, Lauren N; Hill, Audra J; Walters, Samantha J; Walters, Ginny; Walters, Mark D

2018-05-02

The aim oft his study was to compare the effects of 10 common exercises to traditional pelvic floor muscle (PFM) contractions (Kegel) on levator hiatus (LH) area and PFM length and strength. This is a cross-sectional study of 15 healthy postpartum women. Ten exercises were studied. These were common variations of leg, core, and back exercises used in yoga, Pilates, strength training, and physical therapy. Each participant performed all 10 exercises at a single visit in 2 examination settings: transperineal ultrasound and perineometry. Ultrasound measured the LH area and PFM length, and perineometry measured the muscle strength (peak squeeze pressure). Kegel generates an increase in squeeze pressure (24.3 cm H2O), shortens the muscles (-0.46 cm) and narrows the LH (-0.13 cm). The bird-dog and plank exercises were not different from Kegel in any measurement. While the leg-lift ultrasound dimensions are similar to Kegel, leg lifts generated peak squeeze pressures stronger than any other exercise (including Kegel). Whereas ultrasound dimensions were similar to Kegel, tucked and untucked squats and thigh adductions generated weaker contractions than Kegel. While crunch generated a squeeze pressure similar to Kegel, the ultrasound dimensions showed a significantly wider LH and longer muscle than Kegel. Bridge, clam, and plié exercises affected the PFMs differently than Kegel in all measures. Bird-dog, plank, and leg-lift exercises should be evaluated as alternative exercises to Kegel as they affect PFM strength and length and LH area similarly to Kegel, and leg lifts generate a stronger contraction than Kegel.

The stability of M(max) and H (max) amplitude over time.

PubMed

McNulty, Penelope A; Shiner, Christine T; Thayaparan, Ganesha K; Burke, David

2012-05-01

The stability of the maximal muscle response (M(max)) is critical to H reflex methodology. It has previously been reported that the amplitude of M(max) declines over time. If reproducible, this finding would have implications for all experimental studies that normalise the output of the motoneurone pool against the M wave. We investigated the effect of time on changes in M(max) and the maximal H reflex (H(max)) evoked at 4-s intervals over 60 min. To identify an influence of homosynaptic depression, we extended the interstimulus interval to 10 s and the time to 100 min. Two recording montages over soleus were used to ensure that interelectrode distance was not a critical factor. The soleus M(max) and H reflex were evoked by stimulation of the tibial nerve in the popliteal fossa in 7 subjects who sat with the knee flexed to 30° and the ankle plantar flexed by ~30°. We found no change in the pooled data for M(max), H(max), a reflex 50% of maximal, or the current required to produce it. However, one subject had a statistically significant increase in M(max) and a concurrent decrease in H(max) regardless of the interstimulus interval. On average, there was no change in the H(max)/M(max) ratio over time. While both M(max) and H(max) may change in response to many factors, these results suggest that, typically, time is not one of them.

Positive Response to Thermobalancing Therapy Enabled by Therapeutic Device in Men with Non-Malignant Prostate Diseases: BPH and Chronic Prostatitis.

PubMed

Aghajanyan, Ivan Gerasimovich; Allen, Simon

2016-04-18

The most common types of non-malignant prostate diseases are benign prostatic hyperplasia (BPH) and chronic prostatitis (CP). The aim of this study was to find out whether thermobalancing therapy with a physiotherapeutic device is effective for BPH and CP. During a 2.5-year period, 124 men with BPH over the age of 55 were investigated. Clinical parameters were tested twice: via the International Prostate Symptom Score (IPSS) and via ultrasound measurement of prostate volume (PV) and uroflowmetry maximum flow rate (Q max ), before and after six months of therapy. In 45 men with CP under the age of 55, the dynamics of the National Institute of Health Chronic Prostatitis Symptom Index (NIH-CPSI) were studied. The results of the investigated index tests in men with BPH confirmed a decrease in IPSS ( p < 0.001), a reduction in PV ( p < 0.001), an increase in Q max ( p < 0.001), and an improvement of quality of life (QoL) ( p < 0.001). NIH-CPSI scores in men with CP indicated positive dynamics. The observed positive changes in IPSS, PV, and Q max in men with BPH and the improvement in NIH-CPSI-QoL in patients with CP after using a physiotherapeutic device for six months as mono-therapy, support the view that thermobalancing therapy with the device can be recommended for these patients. Furthermore, the therapeutic device is free of side effects.

Phantom-to-clinic development of hypofractionated stereotactic body radiotherapy for early-stage glottic laryngeal cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ding, Chuxiong; Chun, Stephen G.; Sumer, Baran D.

The purpose of this study was to commission and clinically test a robotic stereotactic delivery system (CyberKnife, Sunnyvale, CA) to treat early-stage glottic laryngeal cancer. We enrolled 15 patients with cTis-T2N0M0 carcinoma of the glottic larynx onto an institutional review board (IRB)-approved clinical trial. Stereotactic body radiotherapy (SBRT) plans prescribed 45 Gy/10 fractions to the involved hemilarynx. SBRT dosimetry was compared with (1) standard carotid-sparing laryngeal intensity-modulated radiation therapy (IMRT) and (2) selective hemilaryngeal IMRT. Our results demonstrate that SBRT plans improved sparing of the contralateral arytenoid (mean 20.0 Gy reduction, p <0.001), ipsilateral carotid D{sub max} (mean 20.6 Gy reduction, p <0.001), contralateral carotidmore » D{sub max} (mean 28.1 Gy reduction, p <0.001), and thyroid D{sub mean} (mean 15.0 Gy reduction, p <0.001) relative to carotid-sparing IMRT. SBRT also modestly improved dose sparing to the contralateral arytenoid (mean 4.8 Gy reduction, p = 0.13) and spinal cord D{sub max} (mean 4.9 Gy reduction, p = 0.015) relative to selective hemilaryngeal IMRT plans. This “phantom-to-clinic” feasibility study confirmed that hypofractionated SBRT treatment for early-stage laryngeal cancer can potentially spare dose to adjacent normal tissues relative to current IMRT standards. Clinical efficacy and toxicity correlates continue to be collected through an ongoing prospective trial.« less

RF Induced Nonlinear Effects In High-Speed Electronics

DTIC Science & Technology

2006-07-01

Typ Max Min Typ Max Min Typ Max Min Typ Max Vcc 3 4.5 5.5 4.5 5.5 2 4.5 5.5 4.5 5 5.5 Vil (max) 0.9 1.35 1.65 0.8 0.5 0.9 1.65 0.8 Vih (min) 2.1 3.15...Min Typ Max Min Typ Max Min Typ Max Vcc 1.65 2.3 3.6 2 4.6 6 4.5 5.5 2 3.6 Vil (max) 0.35*Vcc 0.7 0.8 0.3 0.9 1.2 0.8 0.8 0.8 0.7 0.8 Vih (min) 0.65*Vcc...Min Typ Max Vcc 1.65 3.6 2 3 3.6 2 5.5 Vil (max) 0.8 0.5 0.8 0.8 0.5 0.3*Vcc 0.3*Vcc Vih (min) 2 1.5 2 2.4 1.5 0.7*Vcc 0.7*Vcc Vol [V] 0.2 1.9 2.9 2.58

Prospects for the future investigations of Mercury by the BepiColombo Laser Altimeter (BELA)

NASA Astrophysics Data System (ADS)

Steinbrügge, Gregor; Stark, Alexander; Hussmann, Hauke; Wickhusen, Kai; Oberst, Jürgen

2017-04-01

The flight model of the BepiColombo Laser Altimeter (BELA) has recently been delivered for integration on the Mercury Planetary Orbiter (MPO). We performed numerical simulations of the instrument performance expected in flight based on the measured BELA flight model (FM) parameters. In particular, we study measurement performance of topography, slopes, albedo, and roughness. Further, we analyzed the orbit evolution of the MPO based on most recent Mercury gravity data from MESSENGER. This allows us to estimate local and global topographic coverage, as well as the potential for estimates of the tidal Love number h2. Also possible implications of BELA science data on Mercury's interior structure, especially on the core radius and the mantle rheology, will be assessed. BELA is built by the Institute of Physics of the University of Bern and the DLR Institute of Planetary Research in cooperation with the Instituto de Astrofisica de Andalucia of the Consejo Superior de Investigaciones Cientificas (CSIC) and the Max-Planck-Institute for Solar System Research (MPS).

Der deutsche Röntgensatellit ABRIXAS: Mission und wissenschaftliche Zielsetzung.

NASA Astrophysics Data System (ADS)

Predehl, P.

ABRIXAS (A BRoad band Imaging X-ray All-sky Survey) ist ein Röntgensatellit mit sieben 27-fach genesteten Wolterteleskopen, die sich in ihren Brennpunkten eine pn-CCD Kamera teilen. ABRIXAS soll im Frühjahr 1999 auf einer russischen Cosmos-Rakete gestartet werden und die erste abbildende Himmelsdurchmusterung oberhalb von 2.4 keV durchführen. Man erwartet während der dreijährigen Mission wenigstens 10.000 neue Röntgenquellen zu entdecken. Dies sind vor allem solche Quellen, die durch vorgelagerte Staub- und Gasschichten für den ABRIXAS-Vorgänger ROSAT unsichtbar blieben. Darüber hinaus wird ABRIXAS hervorragend geeignet sein, ausgedehnte, diffuse Quellen spektroskopisch zu studieren und Intensitätsvariationen von Röntgenquellen auf sehr unterschiedlichen Zeitskalen zu untersuchen. Das Projekt ist eine wissenschaftliche Zusammenarbeit zwischen dem Astrophysikalischen Institut Potsdam (AIP), dem Institut für Astronomie und Astrophysik der Universität Tübingen (IAAT) und dem Max-Planck-Institut für extraterrestrische Physik (MPE).

MaxReport: An Enhanced Proteomic Result Reporting Tool for MaxQuant.

PubMed

Zhou, Tao; Li, Chuyu; Zhao, Wene; Wang, Xinru; Wang, Fuqiang; Sha, Jiahao

2016-01-01

MaxQuant is a proteomic software widely used for large-scale tandem mass spectrometry data. We have designed and developed an enhanced result reporting tool for MaxQuant, named as MaxReport. This tool can optimize the results of MaxQuant and provide additional functions for result interpretation. MaxReport can generate report tables for protein N-terminal modifications. It also supports isobaric labelling based relative quantification at the protein, peptide or site level. To obtain an overview of the results, MaxReport performs general descriptive statistical analyses for both identification and quantification results. The output results of MaxReport are well organized and therefore helpful for proteomic users to better understand and share their data. The script of MaxReport, which is freely available at http://websdoor.net/bioinfo/maxreport/, is developed using Python code and is compatible across multiple systems including Windows and Linux.

Establishment of a Quantitative Medical Technology Evaluation System and Indicators within Medical Institutions.

PubMed

Wu, Suo-Wei; Chen, Tong; Pan, Qi; Wei, Liang-Yu; Wang, Qin; Li, Chao; Song, Jing-Chen; Luo, Ji

2018-06-05

The development and application of medical technologies reflect the medical quality and clinical capacity of a hospital. It is also an effective approach in upgrading medical service and core competitiveness among medical institutions. This study aimed to build a quantitative medical technology evaluation system through questionnaire survey within medical institutions to perform an assessment to medical technologies more objectively and accurately, and promote the management of medical quality technologies and ensure the medical safety of various operations among the hospitals. A two-leveled quantitative medical technology evaluation system was built through a two-round questionnaire survey of chosen experts. The Delphi method was applied in identifying the structure of evaluation system and indicators. The judgment of the experts on the indicators was adopted in building the matrix so that the weight coefficient and maximum eigenvalue (λ max), consistency index (CI), and random consistency ratio (CR) could be obtained and collected. The results were verified through consistency tests, and the index weight coefficient of each indicator was conducted and calculated through analytical hierarchy process. Twenty-six experts of different medical fields were involved in the questionnaire survey, 25 of whom successfully responded to the two-round research. Altogether, 4 primary indicators (safety, effectiveness, innovativeness, and benefits), as well as 13 secondary indicators, were included in the evaluation system. The matrix is built to conduct the λ max, CI, and CR of each expert in the survey, and the index weight coefficients of primary indicators were 0.33, 0.28, 0.27, and 0.12, respectively, and the index weight coefficients of secondary indicators were conducted and calculated accordingly. As the two-round questionnaire survey of experts and statistical analysis were performed and credibility of the results was verified through consistency evaluation test, the study established a quantitative medical technology evaluation system model and assessment indicators within medical institutions based on the Delphi method and analytical hierarchy process. Moreover, further verifications, adjustments, and optimizations of the system and indicators will be performed in follow-up studies.

Parametric vs. non-parametric statistics of low resolution electromagnetic tomography (LORETA).

PubMed

Thatcher, R W; North, D; Biver, C

2005-01-01

This study compared the relative statistical sensitivity of non-parametric and parametric statistics of 3-dimensional current sources as estimated by the EEG inverse solution Low Resolution Electromagnetic Tomography (LORETA). One would expect approximately 5% false positives (classification of a normal as abnormal) at the P < .025 level of probability (two tailed test) and approximately 1% false positives at the P < .005 level. EEG digital samples (2 second intervals sampled 128 Hz, 1 to 2 minutes eyes closed) from 43 normal adult subjects were imported into the Key Institute's LORETA program. We then used the Key Institute's cross-spectrum and the Key Institute's LORETA output files (*.lor) as the 2,394 gray matter pixel representation of 3-dimensional currents at different frequencies. The mean and standard deviation *.lor files were computed for each of the 2,394 gray matter pixels for each of the 43 subjects. Tests of Gaussianity and different transforms were computed in order to best approximate a normal distribution for each frequency and gray matter pixel. The relative sensitivity of parametric vs. non-parametric statistics were compared using a "leave-one-out" cross validation method in which individual normal subjects were withdrawn and then statistically classified as being either normal or abnormal based on the remaining subjects. Log10 transforms approximated Gaussian distribution in the range of 95% to 99% accuracy. Parametric Z score tests at P < .05 cross-validation demonstrated an average misclassification rate of approximately 4.25%, and range over the 2,394 gray matter pixels was 27.66% to 0.11%. At P < .01 parametric Z score cross-validation false positives were 0.26% and ranged from 6.65% to 0% false positives. The non-parametric Key Institute's t-max statistic at P < .05 had an average misclassification error rate of 7.64% and ranged from 43.37% to 0.04% false positives. The nonparametric t-max at P < .01 had an average misclassification rate of 6.67% and ranged from 41.34% to 0% false positives of the 2,394 gray matter pixels for any cross-validated normal subject. In conclusion, adequate approximation to Gaussian distribution and high cross-validation can be achieved by the Key Institute's LORETA programs by using a log10 transform and parametric statistics, and parametric normative comparisons had lower false positive rates than the non-parametric tests.

Comparison of the 1.5 Mile Run Times at 7,200 Feet and Simulated 850 Feet in a Hyperoxic Room

DTIC Science & Technology

2012-03-01

Maximal Oxygen Update ( VO2 max) Test ......................................... 7 Figure 3 - VO2 Max results for Male, Female and All Subjects. * p...0.001 between Male and Female VO2 ’s. ............................................................. 11 Figure 4 - VO2 Max vs Predicted VO2 Max at 850...and 7,200 Feet ................. 12 Figure 5 - Actual VO2 Max vs Predicted VO2 Max at ALT (7,200 Feet) ....... 13 Figure 6 - VO2 Max vs Predicted

Saphenous vein graft near-infrared spectroscopy imaging insights from the lipid core plaque association with clinical events near-infrared spectroscopy (ORACLE-NIRS) registry.

PubMed

Danek, Barbara A; Karatasakis, Aris; Alame, Aya J; Nguyen-Trong, Phuong-Khanh J; Karacsonyi, Judit; Rangan, Bavana; Roesle, Michele; Atwell, Amy; Resendes, Erica; Martinez-Parachini, Jose Roberto; Iwnetu, Rahel; Kalsaria, Pratik; Siddiqui, Furqan; Muller, James E; Banerjee, Subhash; Brilakis, Emmanouil

2017-05-01

We sought to examine near-infrared spectroscopy (NIRS) imaging findings of aortocoronary saphenous vein grafts (SVGs). SVGs are prone to develop atherosclerosis similar to native coronary arteries. They have received little study using NIRS. We examined the clinical characteristics and imaging findings from 43 patients who underwent NIRS imaging of 45 SVGs at our institution between 2009 and 2016. The mean patient age was 67 ± 7 years and 98% were men, with high prevalence of diabetes mellitus (56%), hypertension (95%), and dyslipidemia (95%). Mean SVG age was 7 ± 7 years, mean SVG lipid core burden index (LCBI) was 53 ± 60 and mean maxLCBI 4 mm was 194 ± 234. Twelve SVGs (27%) had lipid core plaques (2 yellow blocks on the block chemogram), with a higher prevalence in SVGs older than 5 years (46% vs. 5%, P = 0.002). Older SVG age was associated with higher LCBI (r = 0.480, P < 0.001) and higher maxLCBI 4 mm (r = 0.567, P < 0.001). On univariate analysis, greater annual total cholesterol exposure was associated with higher SVG LCBI (r = 0.30, P = 0.042) and annual LDL-cholesterol and triglyceride exposure were associated with higher SVG maxLCBI 4 mm (LDL-C: r = 0.41, P = 0.020; triglycerides: r = 0.36, P = 0.043). On multivariate analysis, the only independent predictor of SVG LCBI and maxLCBI 4mm was SVG age. SVG percutaneous coronary intervention was performed in 63% of the patients. An embolic protection device was used in 96% of SVG PCIs. Periprocedural myocardial infarction occurred in one patient. Older SVG age and greater lipid exposure are associated with higher SVG lipid burden. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Predictor of Severe Gastroduodenal Toxicity After Stereotactic Body Radiotherapy for Abdominopelvic Malignancies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bae, Sun Hyun; Kim, Mi-Sook, E-mail: mskim@kcch.re.kr; Cho, Chul Koo

2012-11-15

Purpose: To identify the predictors for the development of severe gastroduodenal toxicity (GDT) in patients treated with stereotactic body radiotherapy (SBRT) using 3 fractionations for abdominopelvic malignancies. Methods and Materials: From 2001 to 2011, 202 patients with abdominopelvic malignancies were treated with curative-intent SBRT. Among these patients, we retrospectively reviewed the clinical records of 40 patients with the eligibility criteria as follows: 3 fractionations, follow-up period {>=}1 year, absence of previous radiation therapy (RT) history or combination of external-beam RT and the presence of gastroduodenum (GD) that received a dose higher than 20% of prescribed dose. The median SBRT dosemore » was 45 Gy (range, 33-60 Gy) with 3 fractions. We analyzed the clinical and dosimetric parameters, including multiple dose-volume histogram endpoints: V{sub 20} (volume of GD that received 20 Gy), V{sub 25}, V{sub 30}, V{sub 35}, and D{sub max} (the maximum point dose). The grade of GDT was defined by the National Cancer Institute Common Toxicity Criteria version 4.0, and GDT {>=}grade 3 was defined as severe GDT. Results: The median time to the development of severe GDT was 6 months (range, 3-12 months). Severe GDT was found in 6 patients (15%). D{sub max} was the best dosimetric predictor for severe GDT. D{sub max} of 35 Gy and 38 Gy were respectively associated with a 5% and 10% probability of the development of severe GDT. A history of ulcer before SBRT was the best clinical predictor on univariate analysis (P=.0001). Conclusions: We suggest that D{sub max} is a valuable predictor of severe GDT after SBRT using 3 fractionations for abdominopelvic malignancies. A history of ulcer before SBRT should be carefully considered as a clinical predictor, especially in patients who receive a high dose to GD.« less

Re-engineering Ammunition Residue Management in IMCOM-SE

DTIC Science & Technology

2008-06-01

Max Accoutability ) Non-Automatic Return Item Recycling (OBJ: Max Items, Max Profit) Regionalize Store Brass (OBJ: Min Time) Demilitarize... Accoutability ) Non-Automatic Return Item Recycling (OBJ: Max Items, Max Profit) Regionalize Store Brass (OBJ: Min Time) Demilitarize Brass (OBJ: Min

PREFACE: Sixth International Conference on Dissociative Recombination: Theory, Experiments and Applications

NASA Astrophysics Data System (ADS)

Wolf, Andreas; Lammich, Lutz; Schmelcher, Peter

2005-01-01

Dissociative recombination between electrons and molecular ions is an elementary reaction in electron-induced chemistry attracting strong attention across discipline boundaries, from fundamental questions of intramolecular dynamics to astrophysics, plasma science, as well as atmospheric and planetary physics. The process is explored on the level of atomic quantum dynamics both experimentally and theoretically, employing cold collisions at temperatures down to 10 Kelvin involving small molecules or also very large systems ranging up to biomolecules. Dissociative recombination (DR) and related processes, such as dissociative excitation, collisional cooling of vibrations and rotations, photodissociation via high-lying electronic states, resonant electron attachment, and electron-induced processes in large molecules and clusters, are studied by a variety of experimental methods, including stored and trapped molecular ions, plasma techniques such as stationary and flowing afterglow, and laser spectroscopic diagnostic of molecular excitations. The Sixth International Conference on Dissociative Recombination: Theory, Experiments and Applications (DR2004) was organized by the Research Group on Atomic and Molecular Physics with Stored Ions at the Max-Planck Institute for Nuclear Physics in Heidelberg, Germany, and held near Heidelberg in the town of Mosbach in July 2004. It was attended by about 90 scientists working in atomic and molecular physics, astrophysics, plasma- and biophysics. International Conferences on Dissociative Recombination and related processes were held before at Lake Louise, Alberta, Canada (1988), Saint Jacut, Brittany, France (1992), Ein Gedi, Israel (1995), Nässlingen, Stockholm Archipelago, Sweden (1999), and last within a symposium at the American Chemical Society meeting in Chicago, USA (2001). The presentations of this conference document a strong development of theoretical ideas towards the understanding of DR in particular in polyatomic systems. Strong attention was given to the elementary triatomic benchmark system H3+, characterized by ambitious, complementary experimental projects. Interaction of experiment and theory improves in particular the understanding of non-adiabatic molecular interactions involving electronic continuum states. New experimental techniques focus on a detailed control of the internal molecular excitation on the level of single quantum states, which gives increasing importance to laser interactions and ion storage at cryogenic temperatures. Apart from its place in the series of "DR conferences", this meeting is also the final assembly of the EU Research Training Network "Electron Transfer Reactions" (ETR) which in the period from 2000 to 2004 helped to establish many invaluable links between 15 experimental and theoretical institutes active in the field of DR and related processes. We express our gratitude to the EU for the support through the Research Training Network Programme, which has made possible the attendance of many students and young researchers. Furthermore, generous financial support for this conference was provided by the Max-Planck Institute for Nuclear Physics in Heidelberg. The efficient support of the conference center "Alte Mälzerei", operated by the city of Mosbach, is gratefully acknowledged. Finally we warmly thank the staff and the students of the Max-Planck Institute for Nuclear Physics for the dedicated help during the conference.

[Bavarian mental health reform 1851. An instrument of administrative modernization].

PubMed

Burgmair, Wolfgang; Weber, Matthias M

2008-01-01

By 1850 the reformation of institutional psychiatric care in Bavaria was given the highest priority by monarchy and administration. Cooperating with experts, especially the psychiatrist Karl August von Solbrig, they provided for new asylums to be established throughout Bavaria in a surprisingly short period of time. It was, however, only at personal intervention of King Max II. that the administrative and financial difficulties which had existed since the beginning of the 19th century could be overcome. The planning of asylums done by each administrative district of Bavaria vividly reflects rivalry as well as cooperation between all governmental and professional agencies involved. Modernization of psychiatry was publicly justified by referring to scientism, the need for a more progressive restructuring of administration, and the paternalistic care of the monarchy, whereas, from an administrative point of view, aspects of psychiatric treatment, like what kind of asylum would be best, were rather insignificant. The structures established by means of the alliance between state administration and psychiatric care under the rule of King Max II. had a lasting effect on the further development of Bavaria.

AGU elects 1986 Fellows

NASA Astrophysics Data System (ADS)

Eighteen distinguished scientists have been elected Fellows of AGU. The total number of Fellows elected each year may not exceed 0.1% of the total membership at the time of election.The newly elected Fellows are John D. Bossier, Office of Charting and Geodetic Services, National Oceanic and Atmospheric Administration, Rockville, Md.Ian S. Carmichael, Department of Geology and Geophysics, University of California, Berkeley.Paul J. Crutzen, Max Planck Institute for Chemistry, Mainz, Federal Republic of Germany.Dieter H. Ehhalt, Institute of Atmospheric Chemistry, Jülich, and Department of Geophysics, University of Cologne, Cologne, Federal Republic of Germany.Thomas C. Hanks, U.S. Geological Survey, Menlo Park, Calif.C. G. A. Harrison, Rosenstiel School of Marine and Atmospheric Science, University of Miami, Miami, Fla.Stanley R. Hart, Massachusetts Institute of Technology, Cambridge, Mass.Charles W. Howe, Department of Economics, University of Colorado, Boulder.Charlotte E. Keen, Bedford Institute of Oceanography, Dartmouth, Nova Scotia, Canada.T. J. Kukkamäki, Finnish Geodetic Institute, Helsinki.Ronald T. Merrill, Geophysics Program, University of Washington, Seattle.Pearn P. Niiler, Scripps Institution of Oceanography, La Jolla, Calif.Mervyn S. Paterson, Research School of Earth Sciences, Australian National University, Canberra.Joseph Pedlosky, Woods Hole Oceanographic Institution, Woods Hole, Mass.W. R. Peltier, Department of Physics, University of Toronto , Toronto , Canada.Raymond G. Roble, Solar Variability Section, High-Altitude Observatory, National Center for Atmospheric Research, Boulder, Colo.David J. Stevenson, Division of Geological and Planetary Sciences, California Institute of Technology, Pasadena.David A. Woolhiser, Southwest Watershed Research Center, Tucson, Ariz.

Continuum kinetic modeling of the tokamak plasma edge

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dorf, M. A.; Dorr, M. R.; Hittinger, J. A.

2016-05-15

The first 4D (axisymmetric) high-order continuum gyrokinetic transport simulations that span the magnetic separatrix of a tokamak are presented. The modeling is performed with the COGENT code, which is distinguished by fourth-order finite-volume discretization combined with mapped multiblock grid technology to handle the strong anisotropy of plasma transport and the complex X-point divertor geometry with high accuracy. The calculations take into account the effects of fully nonlinear Fokker-Plank collisions, electrostatic potential variations, and anomalous radial transport. Topics discussed include: (a) ion orbit loss and the associated toroidal rotation and (b) edge plasma relaxation in the presence of anomalous radial transport.

Apple F-Box Protein MdMAX2 Regulates Plant Photomorphogenesis and Stress Response.

PubMed

An, Jian-Ping; Li, Rui; Qu, Feng-Jia; You, Chun-Xiang; Wang, Xiao-Fei; Hao, Yu-Jin

2016-01-01

MAX2 (MORE AXILLARY GROWTH2) is involved in diverse physiological processes, including photomorphogenesis, the abiotic stress response, as well as karrikin and strigolactone signaling-mediated shoot branching. In this study, MdMAX2, an F-box protein that is a homolog of Arabidopsis MAX2, was identified and characterized. Overexpression of MdMAX2 in apple calli enhanced the accumulation of anthocyanin. Ectopic expression of MdMAX2 in Arabidopsis exhibited photomorphogenesis phenotypes, including increased anthocyanin content and decreased hypocotyl length. Further study indicated that MdMAX2 might promote plant photomorphogenesis by affecting the auxin signaling as well as other plant hormones. Transcripts of MdMAX2 were noticeably up-regulated in response to NaCl and Mannitol treatments. Moreover, compared with the wild-type, the MdMAX2 -overexpressing apple calli and Arabidopsis exhibited increased tolerance to salt and drought stresses. Taken together, these results suggest that MdMAX2 plays a positive regulatory role in plant photomorphogenesis and stress response.

Polish and European SST Assets: the Solaris-Panoptes Global Network of Robotic Telescopes and the Borowiec Satellite Laser Ranging System

NASA Astrophysics Data System (ADS)

Konacki, M.; Lejba, P.; Sybilski, P.; Pawłaszek, R.; Kozłowski, S.; Suchodolski, T.; Litwicki, M.; Kolb, U.; Burwitz, V.; Baader, J.; Groot, P.; Bloemen, S.; Ratajczak, M.; Helminiak, K.; Borek, R.; Chodosiewicz, P.

2016-09-01

We present the assets of the Nicolaus Copernicus Astronomical Center, Space Research Center (both of the Polish Academy of Sciences), two Polish companies Sybilla Technologies, Cillium Engineering and a non-profit research foundation Baltic Institute of Technology. These assets are enhanced by telescopes belonging to The Open University (UK), the Max Planck Institute for Extraterrestrial Physics and in the future the Radboud University. They consist of the Solaris-Panoptes global network of optical robotic telescopes and the satellite laser ranging station in Borowiec, Poland. These assets will contribute to the Polish and European Space Surveillance and Tracking (SST) program. The Solaris component is composed of four autonomous observatories in the Southern Hemisphere. Solaris nodes are located at the South African Astronomical Observatory (Solaris-1 and Solaris-2), Siding Spring Observatory, Australia (Solaris-3) and Complejo Astronomico El Leoncito, Argentina (Solaris-4). They are equipped with 0.5-m telescopes on ASA DDM-160 direct drive mounts, Andor iKon-L cameras and housed in 3.5-m Baader Planetarium (BP) clamshell domes. The Panoptes component is a network of telescopes operated by software from Sybilla Technologies. It currently consists of 4 telescopes at three locations, all on GM4000 mounts. One 0.36-m (Panoptes-COAST, STL- 1001E camera, 3.5 BP clamshell dome) and one 0.43-m (Panoptes-PIRATE, FLI 16803 camera, 4.5-m BP clamshell dome, with planned exchange to 0.63-m) telescope are located at the Teide Observatory (Tenerfie, Canary Islands), one 0.6-m (Panoptes-COG, SBIG STX 16803 camera, 4.5-m BP clamshell dome) telescope in Garching, Germany and one 0.5-m (Panoptes-MAM, FLI 16803 camera, 4.5-m BP slit dome) in Mammendorf, Germany. Panoptes-COAST and Panoptes-PIRATE are owned by The Open University (UK). Panoptes-COG is owned by the Max Planck Institute

[Neuropathological research on organs of patients of the "Heil- und pflegeanstalt" (state hospital) Günzburg].

PubMed

Steger, F; Strube, W; Becker, T

2011-03-31

The two Kaiser Wilhelm-Institutes (KWI) in Berlin (1914, new building 1931) and in Munich (1917, new building 1926-28), specialized on pathologic anatomical as well as psychiatric genetic research, were set up before times of National Socialism. Data evaluation is based on patient documents and annual reports of the archive of today's district hospital Günzburg and on patient documents (copies) of the historical archive of today's Max-Planck Institute of Psychiatry. The KWI in Munich was indirectly provided with brain material by Bavarian "Heil- und Pflegeanstalten" (state hospitals) including the state hospital Günzburg. During National Socialism patients' organs were sent from the "Heil- und Pflegeanstalt" (state hospital) Günzburg to the KWI in Munich for the purpose of conducting research. Commemorating patients' fates and clarifying what happened defines a place of remembrance.

The effects of breathing a helium-oxygen gas mixture on maximal pulmonary ventilation and maximal oxygen consumption during exercise in acute moderate hypobaric hypoxia.

PubMed

Ogawa, Takeshi; Calbet, Jose A L; Honda, Yasushi; Fujii, Naoto; Nishiyasu, Takeshi

2010-11-01

To test the hypothesis that maximal exercise pulmonary ventilation (VE max) is a limiting factor affecting maximal oxygen uptake (VO2 max) in moderate hypobaric hypoxia (H), we examined the effect of breathing a helium-oxygen gas mixture (He-O(2); 20.9% O(2)), which would reduce air density and would be expected to increase VE max. Fourteen healthy young male subjects performed incremental treadmill running tests to exhaustion in normobaric normoxia (N; sea level) and in H (atmospheric pressure equivalent to 2,500 m above sea level). These exercise tests were carried out under three conditions [H with He-O(2), H with normal air and N] in random order. VO2 max and arterial oxy-hemoglobin saturation (SaO(2)) were, respectively, 15.2, 7.5 and 4.0% higher (all p < 0.05) with He-O(2) than with normal air (VE max, 171.9 ± 16.1 vs. 150.1 ± 16.9 L/min; VO2 max, 52.50 ± 9.13 vs. 48.72 ± 5.35 mL/kg/min; arterial oxyhemoglobin saturation (SaO(2)), 79 ± 3 vs. 76 ± 3%). There was a linear relationship between the increment in VE max and the increment in VO2 max in H (r = 0.77; p < 0.05). When subjects were divided into two groups based on their VO2 max, both groups showed increased VE max and SaO(2) in H with He-O(2), but VO2 max was increased only in the high VO2 max group. These findings suggest that in acute moderate hypobaric hypoxia, air-flow resistance can be a limiting factor affecting VE max; consequently, VO2 max is limited in part by VE max especially in subjects with high VO2 max.

Significance of the velocity at VO2max and time to exhaustion at this velocity.

PubMed

Billat, L V; Koralsztein, J P

1996-08-01

In 1923, Hill and Lupton pointed out that for Hill himself, 'the rate of oxygen intake due to exercise increases as speed increases, reaching a maximum for the speeds beyond about 256 m/min. At this particular speed, for which no further increases in O2 intake can occur, the heart, lungs, circulation, and the diffusion of oxygen to the active muscle-fibres have attained their maximum activity. At higher speeds the requirement of the body for oxygen is far higher but cannot be satisfied, and the oxygen debt continuously increases'. In 1975, this minimal velocity which elicits maximal oxygen uptake (VO2max) was called 'critical speed' and was used to measure the maximal aerobic capacity (max Eox), i.e. the total oxygen consumed at VO2max. This should not be confused with the term 'critical power' which is closes to the power output at the 'lactate threshold'. In 1984, the term 'velocity at VO2max' and the abbreviation 'vVO2max' was introduced. It was reported that vVO2max is a useful variable that combines VO2max and economy into a single factor which can identify aerobic differences between various runners or categories of runners. vVO2max explained individual differences in performance that VO2max or running economy alone did not. Following that, the concept of a maximal aerobic running velocity (Vamax in m/sec) was formulated. This was a running velocity at which VO2max occurred and was calculated as the ratio between VO2max (ml/kg/min) minus oxygen consumption at rest, and the energy cost of running (ml/kg/sec). There are many ways to determine the velocity associated with VO2max making it difficult to compare maintenance times. In fact, the time to exhaustion (tlim) at vVO2max is reproducible in an individual, however, there is a great variability among individuals with a low coefficient of variation for vVO2max. For an average value of about 6 minutes, the coefficient of variation is about 25%. It seems that the lactate threshold which is correlated with the tlim at vVO2max can explain this difference among individuals, the role of the anaerobic contribution being significant. An inverse relationship has been found between tlim at vVO2max and VO2max, and a positive one between vVO2max and the velocity at the lactate threshold expressed as a fraction of vVO2max. These results are similar for different sports (e.g. running, cycling, kayaking, swimming). It seems that the real time spent at VO2max is significantly different from an exhaustive run at a velocity close to vVO2max (105% vVO2max). However, the minimal velocity which elicits VO2max, and the tlim at this velocity appear to convey valuable information when analysing a runner's performance over 1500m to a marathon.

In vitro and in vivo flavor release from intact and fresh-cut apple in relation with genetic, textural, and physicochemical parameters.

PubMed

Ting, Valentina J L; Soukoulis, Christos; Silcock, Patrick; Cappellin, Luca; Romano, Andrea; Aprea, Eugenio; Bremer, Phil J; Märk, Tilmann D; Gasperi, Flavia; Biasioli, Franco

2012-11-01

Flavor release from 6 commercial apple cultivars (Fuji, Granny Smith, Golden Delicious, Jonagold, Morgen Dallago, and Red Delicious) under static conditions (intact or fresh-cut samples) and during consumption of fresh-cut samples (nosespace) was determined by proton transfer reaction mass spectrometry. Textural (firmness, fracturability, flesh elasticity, and rupture) and physicochemical (pH, acidity, and water content) properties of the apples were also measured. Static headspace analysis of intact fruits revealed Fuji and Granny Smith apples had the lowest concentration for all measured flavor compounds (esters, aldehydes, alcohols, and terpenes), whereas Red Delicious apples had the highest. Fresh-cut samples generally showed a significant increase in total volatile compounds with acetaldehyde being most abundant. However, compared to intact fruits, cut Golden and Red Delicious apples had a lower intensity for ester related peaks. Five parameters were extracted from the nosespace data of peaks related to esters (m/z 43, 61), acetaldehyde (m/z 45), and ethanol (m/z 47): 2 associated with mastication (duration of mastication-t(con); time required for first swallowing event-t(swal)), and 3 related with in-nose volatile compound concentration (area under the curve-AUC; maximum intensity-I(max); time for achieving I(max)-t(max)). Three different behaviors were identified in the nosespace data: a) firm samples with low AUC and t(swal) values (Granny Smith, Fuji), b) mealy samples with high AUC, I(max), t(swal) values, and low t(con) (Morgen Dallago, Golden Delicious), and c) firm samples with high AUC and I(max) values (Red Delicious). Strengths and limitations of the methodology are discussed. Volatile compounds play a fundamental role in the perceived quality of food. Using apple cultivars, this research showed that in vivo proton transfer reaction mass spectrometry (PTR-MS) could be used to determine the relationship between the release of volatile flavor compounds and the physicochemical parameters of a real food matrix. This finding suggests that in vivo PTR-MS coupled with traditional physicochemical measurements could be used to yield information on flavor release from a wide range of food matrices and help in the development of strategies to enhance food flavor and quality. © 2012 Institute of Food Technologists®

Multiple variables explain the variability in the decrement in VO2max during acute hypobaric hypoxia.

PubMed

Robergs, R A; Quintana, R; Parker, D L; Frankel, C C

1998-06-01

We used multiple regression analyses to determine the relationships between the decrement in sea level (SL, 760 Torr) VO2max during hypobaric hypoxia (HH) and variables that could alter or be related to the decrement in VO2max. HH conditions consisted of 682 Torr, 632 Torr, and 566 Torr, and the measured independent variables were SL-VO2max, SL lactate threshold (SL-LT), the change in hemoglobin saturation at VO2max between 760 and 566 Torr (delta SaO2max), lean body mass (LBM), and gender. Male (N = 14) and female (N = 14) subjects of varied fitness, training status, and residential altitude (1,640-2,460 m) completed cycle ergometry tests of VO2max at each HH condition under randomized and single-blinded conditions. VO2max decreased significantly from 760 Torr after 682 Torr (approximately 915 m) (3.5 +/- 0.9 to 3.4 +/- 0.8 L.min-1, P = 0.0003). Across all HH conditions, the slope of the relative decrement in VO2max (%VO2max) during HH was -9.2%/100 mm Hg (-8.1%/1000 m) with an initial decrease from 100% estimated to occur below 705 Torr (610 m). Step-wise multiple regression revealed that SL-VO2max, SL-LT, delta SaO2max, LBM, and gender each significantly combined to account for 89.03% of the variance in the decrement in VO2max (760-566 Torr) (P < 0.001). Individuals who have a combination of a large SL-VO2max, a small SL-LT (VO2, L.min-1), greater reductions in delta SaO2max, a large LBM, and are male have the greatest decrement in VO2max during HH. The unique variance explanation afforded by SL-LT, LBM, and gender suggests that issues pertaining to oxygen diffusion within skeletal muscle may add to the explanation of between subjects variability in the decrement in VO2max during HH.

Lactate kinetics in handcycling under various exercise modalities and their relationship to performance measures in able-bodied participants.

PubMed

Quittmann, Oliver J; Abel, Thomas; Zeller, Sebastian; Foitschik, Tina; Strüder, Heiko K

2018-05-03

The aim of this study was to expand exercise testing in handcycling by (1) examining different approaches to determine lactate kinetics in handcycling under various exercise modalities and (2) identifying relationships between parameters of lactate kinetics and selected performance measures. Twelve able-bodied nationally competitive triathletes performed a familiarisation, a sprint test, an incremental step test, and a continuous load trial at a power output corresponding to a lactate concentration (La) of 4 mmol l -1 (PO 4 ) in a racing handcycle that was mounted on an ergometer. During the tests, La and heart rate (HR) were determined. As performance measures, maximal power output during the 15-s All-Out sprint test (PO max,AO15 ) and maximal power output during the incremental test (PO max,ST ) were determined. As physiological parameters, coefficients of lactate kinetics, maximal lactate accumulation rate ([Formula: see text]La max ), maximal La following the sprint test and incremental test (La max,AO15 , La max,ST ) and the increase in La within the last 20 min of the continuous trial (La Crit,CT ) were determined. Mean values of PO max,AO15 (545.6 ± 69.9 W), PO max,ST (131.3 ± 14.9 W), PO 4 (86.73 ± 12.32 W), [Formula: see text]La max (0.45 ± 0.11 mmol l -1  s -1 ), La max,AO15 (6.64 ± 1.32 mmol l -1 ), La max,ST (9.64 ± 2.24 mmol l -1 ) and La Crit,CT (0.74 ± 0.74 mmol l -1 ) were in accordance to literature. [Formula: see text]La max was positively correlated with La max,AO15 and PO max,AO15 and negatively correlated with PO max,ST . PO max,ST was negatively correlated with La max,AO15 . PO 4 was negatively correlated with La max,ST . [Formula: see text]La max was identified as a promising parameter for exercise testing in handcycling that can be supplemented by other parameters describing lactate kinetics following a sprint test.

Characteristics of the ocean simulations in the Max Planck Institute Ocean Model (MPIOM) the ocean component of the MPI-Earth system model

NASA Astrophysics Data System (ADS)

Jungclaus, J. H.; Fischer, N.; Haak, H.; Lohmann, K.; Marotzke, J.; Matei, D.; Mikolajewicz, U.; Notz, D.; von Storch, J. S.

2013-06-01

MPI-ESM is a new version of the global Earth system model developed at the Max Planck Institute for Meteorology. This paper describes the ocean state and circulation as well as basic aspects of variability in simulations contributing to the fifth phase of the Coupled Model Intercomparison Project (CMIP5). The performance of the ocean/sea-ice model MPIOM, coupled to a new version of the atmosphere model ECHAM6 and modules for land surface and ocean biogeochemistry, is assessed for two model versions with different grid resolution in the ocean. The low-resolution configuration has a nominal resolution of 1.5°, whereas the higher resolution version features a quasiuniform, eddy-permitting global resolution of 0.4°. The paper focuses on important oceanic features, such as surface temperature and salinity, water mass distribution, large-scale circulation, and heat and freshwater transports. In general, these integral quantities are simulated well in comparison with observational estimates, and improvements in comparison with the predecessor system are documented; for example, for tropical variability and sea ice representation. Introducing an eddy-permitting grid configuration in the ocean leads to improvements, in particular, in the representation of interior water mass properties in the Atlantic and in the representation of important ocean currents, such as the Agulhas and Equatorial current systems. In general, however, there are more similarities than differences between the two grid configurations, and several shortcomings, known from earlier versions of the coupled model, prevail.

Definitive salvage radiation therapy and chemoradiation therapy for lymph node oligo-recurrence of esophageal cancer: a Japanese multi-institutional study of 237 patients.

PubMed

Yamashita, Hideomi; Jingu, Keiichi; Niibe, Yuzuru; Katsui, Kuniaki; Matsumoto, Toshihiko; Nishina, Tomohiro; Terahara, Atsuro

2017-02-20

This study evaluated the treatment results of lymph node (LN) oligo-recurrence in esophageal cancer patients treated with salvage radiotherapy (RT) in a multi-institutional retrospective study. Eligibility criteria for this retrospective analysis were: the primary lesion of esophageal cancer was controlled; from one to five LN recurrences; total RT dose ≥45 Gy to exclude palliative RT; without recurrence other than LN; and salvage RT for LN recurrence was given between January 2000 and April 2015. The median follow-up time for the 93 living patients was 29.6 months. Two hundred thirty-seven patients were matched in five hospitals. The 3-year overall survival (OS) was 37%, local control was 45%, progression-free survival was 24%, and esophageal cancer-specific survival was 42%. On univariate analysis for OS, combined chemotherapy (p = 0.000055), disease-free interval (DFI) ≥12 months (p = 0.0013), LN max diameter ≤22 mm (p = 0.0052), and Karnofsky performance status ≥80% (p = 0.030) were associated with a significantly better prognosis. On multivariate analysis, significant differences were seen for combined chemotherapy (p = 0.000018), DFI (p = 0.0027), and LN max diameter (p = 0.018). LN oligo-recurrence following treatment for esophageal cancer was not a terminal-stage event. Moreover, cure may be possible by chemoradiation therapy with a long DFI (≥12 months) and small size (≤22 mm).

Role of maximal heart rate and arterial O2 saturation on the decrement of VO2max in moderate acute hypoxia in trained and untrained men.

PubMed

Mollard, P; Woorons, X; Letournel, M; Cornolo, J; Lamberto, C; Beaudry, M; Richalet, J-P

2007-03-01

We aimed to evaluate 1) the altitude where maximal heart rate (HR (max)) decreases significantly in both trained and untrained subjects in moderate acute hypoxia, and 2) if the HR (max) decrease could partly explain the drop of V.O (2max). Seventeen healthy males, nine trained endurance athletes (TS) and eight untrained individuals (US) were studied. Subjects performed incremental exercise tests at sea level and at 5 simulated altitudes (1000, 1500, 2500, 3500, 4500 meters). Power output (PO), heart rate (HR), arterial oxygen saturation (SaO (2)), oxygen uptake (V.O (2)), arterialized blood pH and lactate were measured. Both groups showed a progressive reduction in V.O (2max). The decrement in HR (max) (DeltaHR (max)) was significant from 1000 m for TS and 2500 m for US and more important in TS than US (at 1500 m and 3500 m). At maximal exercise, TS had a greater reduction in SaO (2) (DeltaSaO (2)) at each altitude. DeltaHR (max) observed in TS was correlated with DeltaSaO (2). When the two groups were pooled, simple regressions showed that DeltaV.O (2max) was correlated with both DeltaSaO (2) and DeltaHR (max). However, a multiple regression analysis demonstrated that DeltaSaO (2) alone may account for DeltaV.O (2max). Furthermore, in spite of a greater reduction in SaO (2) and HR (max) in TS, no difference was evidenced in relative DeltaV.O (2max) between groups. Thus, in moderate acute hypoxia, the reduction in SaO (2) is the primary factor to explain the drop of V.O (2max) in trained and untrained subjects.

76 FR 20433 - MaxLife Fund Corp.; Order of Suspension of Trading

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-12

... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] MaxLife Fund Corp.; Order of Suspension of... current and accurate information concerning the securities of MaxLife Fund Corp. (``MaxLife'') because of questions that have arisen concerning representations made by MaxLife, the control of its stock, its market...

The influence of evaluation protocol on time spent exercising at a high level of oxygen uptake during continuous cycling.

PubMed

Merry, K L; Glaister, M; Howatson, G; Van Someren, K

2015-10-01

This study evaluated the effects of protocol variation on the time spent exercising at ≥95% V̇O2max during cycle ergometer trials performed at the exercise intensity associated with V̇O2max (iV̇O2max). Nine male triathletes (age: 32±10 years; body mass: 73.3±6.1 kg; stature: 1.79±0.07 m; V̇O2max: 3.58±0.45 L.min(-1)) performed four exercise tests. During tests 1 and 2, participants performed a maximal incremental cycle ergometer test using different stage durations (1 min and 3 min) for the determination of iV̇O2max (1 min) and iV̇O2max (3 min). During tests 3 and 4, participants performed a continuous bout of exhaustive cycling at iV̇O2max (1 min) (CONT1) and iV̇O2max (3 min) (CONT3). iV̇O2max (1 min) was significantly greater (P<0.001) than iV̇O2max (3 min) (340±31 W vs. 299±44 W). Time to exhaustion (TTE) measured during CONT3 was significantly longer (P<0.001) than CONT1 (529±140 s vs. 214±65 s). Time spent at V̇O2max was significantly longer (P=0.036) during CONT3 than CONT1 (146±158 s vs. 11±20 s), and time spent at ≥95% V̇O2max was significantly longer (P=0.005) during CONT3 than CONT1 (326±211 s vs. 57±51 s). These results show that when exercising continuously at iV̇O2max, time spent at ≥95% V̇O2max is influenced by the initial measurement of iV̇O2max.

Ischemic preconditioning of the muscle improves maximal exercise performance but not maximal oxygen uptake in humans.

PubMed

Crisafulli, Antonio; Tangianu, Flavio; Tocco, Filippo; Concu, Alberto; Mameli, Ombretta; Mulliri, Gabriele; Caria, Marcello A

2011-08-01

Brief episodes of nonlethal ischemia, commonly known as "ischemic preconditioning" (IP), are protective against cell injury induced by infarction. Moreover, muscle IP has been found capable of improving exercise performance. The aim of the study was the comparison of standard exercise performances carried out in normal conditions with those carried out following IP, achieved by brief muscle ischemia at rest (RIP) and after exercise (EIP). Seventeen physically active, healthy male subjects performed three incremental, randomly assigned maximal exercise tests on a cycle ergometer up to exhaustion. One was the reference (REF) test, whereas the others were performed after the RIP and EIP sessions. Total exercise time (TET), total work (TW), and maximal power output (W(max)), oxygen uptake (VO(2max)), and pulmonary ventilation (VE(max)) were assessed. Furthermore, impedance cardiography was used to measure maximal heart rate (HR(max)), stroke volume (SV(max)), and cardiac output (CO(max)). A subgroup of volunteers (n = 10) performed all-out tests to assess their anaerobic capacity. We found that both RIP and EIP protocols increased in a similar fashion TET, TW, W(max), VE(max), and HR(max) with respect to the REF test. In particular, W(max) increased by ∼ 4% in both preconditioning procedures. However, preconditioning sessions failed to increase traditionally measured variables such as VO(2max), SV(max,) CO(max), and anaerobic capacity(.) It was concluded that muscle IP improves performance without any difference between RIP and EIP procedures. The mechanism of this effect could be related to changes in fatigue perception.

Age-Predicted Maximal Heart Rate in Recreational Marathon Runners: A Cross-Sectional Study on Fox's and Tanaka's Equations.

PubMed

Nikolaidis, Pantelis T; Rosemann, Thomas; Knechtle, Beat

2018-01-01

Age-based prediction equations of maximal heart rate (HR max ), such as the popular formulas Fox's 220-age, or Tanaka's 208-0.7 × age, have been widely used in various populations. Surprisingly, so far these equations have not been validated in marathon runners, despite the importance of the role of HR max for training purposes in endurance running. The aim of the present study was to examine the validity of Fox and Tanaka equations in a large sample of women and men recreational marathon runners. Participants ( n = 180, age 43.2 ± 8.5 years, VO 2max 46.8 mL/min/kg, finishers in at least one marathon during the last year) performed a graded exercise test on a treadmill, where HR max was measured. Measured HR max correlated largely with age in the total sample ( r = -0.50, p < 0.001), women ( r = -0.60, p < 0.001) and men ( r = -0.53, p < 0.001). In women, a large main effect of method on HR max ( p = 0.001, η 2 = 0.294) was shown with measured HR max lower than Fox-HR max (-4.8 bpm; -8.4, -1.3) and Tanaka-HR max (-4.9 bpm; -8.1, -1.8). In men, a moderate effect of assessment method on HR max was found ( p = 0.001, η 2 = 0.066) with measured HR max higher than Fox-HR max (+2.8; 1.0, 4.6), Tanaka-HR max higher than Fox-HR max (+1.2; 0.7, 1.7). Based on these findings, it was concluded that Fox and Tanaka' formulas overestimated HR max by ~5 bpm in women, whereas Fox underestimated HR max in men by ~3 bpm. Thus, we recommend the further use of Tanaka's formula in men marathon runners. In addition, exercise physiologists and sport scientists should consider the observed differences among various assessment methods when performing exercise testing or prescribing training program relying on HR.

Contrast-to-noise ratio with different settings in a CBCT machine in presence of different root-end filling materials: an in vitro study.

PubMed

Demirturk Kocasarac, Husniye; Helvacioglu Yigit, Dilek; Bechara, Boulos; Sinanoglu, Alper; Noujeim, Marcel

2016-01-01

To compare the contrast-to-noise ratio (CNR) of multiple acquisition settings for four types of retrograde filling materials in CBCT images taken for endodontic surgery follow-up. 20 maxillary central incisors were endodontically treated and obturated with 4 different root-end filling materials: amalgam, mineral trioxide aggregate, SuperEBA(™) (Harry J Bosworth Company, Skokie, IL) and Biodentine™ (Septodont, Saint-Maur-des-Faussés, France). Teeth were placed in a skull and scanned, one by one, with the Planmeca ProMax(®) 3D Max (Planmeca, Helsinki, Finland); at different voltages: 66, 76, 84 and 96 kVp; with low, normal and high resolution and high definition (HD); with and without metal artefact reduction (MAR). Images were analyzed using ImageJ software (National Institutes of Health, Bethesda, MD) to calculate the CNR. The dose-area product was registered, and the effective dose calculated. No statistically significant difference was noted between the four materials. 84 and 96 kVp with low resolution and the use of MAR-generated images that have statistically better CNR than 66 and 76 kVp with HD, normal and high resolutions and without MAR. The use of low resolution also generated the smallest value of effective dose. The best setting for radiographic follow-up in an endodontic surgery with retrograde filling on the Planmeca ProMax is 96 kVp with low resolution and high MAR; this setting produced one of the lowest effective doses.

Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma.

PubMed

Comino-Méndez, Iñaki; Gracia-Aznárez, Francisco J; Schiavi, Francesca; Landa, Iñigo; Leandro-García, Luis J; Letón, Rocío; Honrado, Emiliano; Ramos-Medina, Rocío; Caronia, Daniela; Pita, Guillermo; Gómez-Graña, Alvaro; de Cubas, Aguirre A; Inglada-Pérez, Lucía; Maliszewska, Agnieszka; Taschin, Elisa; Bobisse, Sara; Pica, Giuseppe; Loli, Paola; Hernández-Lavado, Rafael; Díaz, José A; Gómez-Morales, Mercedes; González-Neira, Anna; Roncador, Giovanna; Rodríguez-Antona, Cristina; Benítez, Javier; Mannelli, Massimo; Opocher, Giuseppe; Robledo, Mercedes; Cascón, Alberto

2011-06-19

Hereditary pheochromocytoma (PCC) is often caused by germline mutations in one of nine susceptibility genes described to date, but there are familial cases without mutations in these known genes. We sequenced the exomes of three unrelated individuals with hereditary PCC (cases) and identified mutations in MAX, the MYC associated factor X gene. Absence of MAX protein in the tumors and loss of heterozygosity caused by uniparental disomy supported the involvement of MAX alterations in the disease. A follow-up study of a selected series of 59 cases with PCC identified five additional MAX mutations and suggested an association with malignant outcome and preferential paternal transmission of MAX mutations. The involvement of the MYC-MAX-MXD1 network in the development and progression of neural crest cell tumors is further supported by the lack of functional MAX in rat PCC (PC12) cells and by the amplification of MYCN in neuroblastoma and suggests that loss of MAX function is correlated with metastatic potential.

MaxEnt alternatives to pearson family distributions

NASA Astrophysics Data System (ADS)

Stokes, Barrie J.

2012-05-01

In a previous MaxEnt conference [11] a method of obtaining MaxEnt univariate distributions under a variety of constraints was presented. The Mathematica function Interpolation[], normally used with numerical data, can also process "semi-symbolic" data, and Lagrange Multiplier equations were solved for a set of symbolic ordinates describing the required MaxEnt probability density function. We apply a more developed version of this approach to finding MaxEnt distributions having prescribed β1 and β2 values, and compare the entropy of the MaxEnt distribution to that of the Pearson family distribution having the same β1 and β2. These MaxEnt distributions do have, in general, greater entropy than the related Pearson distribution. In accordance with Jaynes' Maximum Entropy Principle, these MaxEnt distributions are thus to be preferred to the corresponding Pearson distributions as priors in Bayes' Theorem.

Max dD/Dt: A Novel Parameter to Assess Fetal Cardiac Contractility and a Substitute for Max dP/Dt.

PubMed

Fujita, Yasuyuki; Kiyokoba, Ryo; Yumoto, Yasuo; Kato, Kiyoko

2018-07-01

Aortic pulse waveforms are composed of a forward wave from the heart and a reflection wave from the periphery. We focused on this forward wave and suggested a new parameter, the maximum slope of aortic pulse waveforms (max dD/dt), for fetal cardiac contractility. Max dD/dt was calculated from fetal aortic pulse waveforms recorded with an echo-tracking system. A normal range of max dD/dt was constructed in 105 healthy fetuses using linear regression analysis. Twenty-two fetuses with suspected fetal cardiac dysfunction were divided into normal and decreased max dD/dt groups, and their clinical parameters were compared. Max dD/dt of aortic pulse waveforms increased linearly with advancing gestational age (r = 0.93). The decreased max dD/dt was associated with abnormal cardiotocography findings and short- and long-term prognosis. In conclusion, max dD/dt calculated from the aortic pulse waveforms in fetuses can substitute for max dP/dt, an index of cardiac contractility in adults. Copyright © 2018 World Federation for Ultrasound in Medicine and Biology. Published by Elsevier Inc. All rights reserved.

Spanish genetic admixture is associated with larger V(O2) max decrement from sea level to 4338 m in Peruvian Quechua.

PubMed

Brutsaert, Tom D; Parra, Esteban J; Shriver, Mark D; Gamboa, Alfredo; Palacios, Jose-Antonio; Rivera, Maria; Rodriguez, Ivette; León-Velarde, Fabiola

2003-08-01

Quechua in the Andes may be genetically adapted to altitude and able to resist decrements in maximal O2 consumption in hypoxia (DeltaVo2 max). This hypothesis was tested via repeated measures of Vo2 max (sea level vs. 4338 m) in 30 men of mixed Spanish and Quechua origins. Individual genetic admixture level (%Spanish ancestry) was estimated by using ancestry-informative DNA markers. Genetic admixture explained a significant proportion of the variability in DeltaVo2 max after control for covariate effects, including sea level Vo2 max and the decrement in arterial O2 saturation measured at Vo2 max (DeltaSpO2 max) (R2 for admixture and covariate effects approximately 0.80). The genetic effect reflected a main effect of admixture on DeltaVo2 max (P = 0.041) and an interaction between admixture and DeltaSpO2 max (P = 0.018). Admixture predicted DeltaVo2 max only in subjects with a large DeltaSpO2 max (P = 0.031). In such subjects, DeltaVo2 max was 12-18% larger in a subgroup of subjects with high vs. low Spanish ancestry, with least squares mean values (+/-SE) of 739 +/- 71 vs. 606 +/- 68 ml/min, respectively. A trend for interaction (P = 0.095) was also noted between admixture and the decrease in ventilatory threshold at 4338 m. As previously, admixture predicted DeltaVo2 max only in subjects with a large decrease in ventilatory threshold. These findings suggest that the genetic effect on DeltaVo2 max depends on a subject's aerobic fitness. Genetic effects may be more important (or easier to detect) in athletic subjects who are more likely to show gas-exchange impairment during exercise. The results of this study are consistent with the evolutionary hypothesis and point to a better gas-exchange system in Quechua.

Min-Max Spaces and Complexity Reduction in Min-Max Expansions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gaubert, Stephane, E-mail: Stephane.Gaubert@inria.fr; McEneaney, William M., E-mail: wmceneaney@ucsd.edu

2012-06-15

Idempotent methods have been found to be extremely helpful in the numerical solution of certain classes of nonlinear control problems. In those methods, one uses the fact that the value function lies in the space of semiconvex functions (in the case of maximizing controllers), and approximates this value using a truncated max-plus basis expansion. In some classes, the value function is actually convex, and then one specifically approximates with suprema (i.e., max-plus sums) of affine functions. Note that the space of convex functions is a max-plus linear space, or moduloid. In extending those concepts to game problems, one finds amore » different function space, and different algebra, to be appropriate. Here we consider functions which may be represented using infima (i.e., min-max sums) of max-plus affine functions. It is natural to refer to the class of functions so represented as the min-max linear space (or moduloid) of max-plus hypo-convex functions. We examine this space, the associated notion of duality and min-max basis expansions. In using these methods for solution of control problems, and now games, a critical step is complexity-reduction. In particular, one needs to find reduced-complexity expansions which approximate the function as well as possible. We obtain a solution to this complexity-reduction problem in the case of min-max expansions.« less

Alignment and phasing of deployable telescopes

NASA Technical Reports Server (NTRS)

Woolf, N. J.; Ulich, B. L.

1983-01-01

The experiences in coaligning and phasing the Multi-Mirror Telescope (MMT), together with studies in setting up radio telescopes, are presented. These experiences are discussed, and on the basis they furnish, schemes are suggested for coaligning and phasing four large future telescopes with complex primary mirror systems. These telescopes are MT2, a 15-m-equivalent MMT, the University of California Ten Meter Telescope, the 10 m sub-mm wave telescope of the University of Arizona and the Max Planck Institute for Radioastronomy, and the Large Deployable Reflector, a future space telescope for far-IR and sub-mm waves.

Performance testing of an off-plane reflection grating and silicon pore optic spectrograph at PANTER

NASA Astrophysics Data System (ADS)

Marlowe, Hannah; McEntaffer, Randall L.; Allured, Ryan; DeRoo, Casey T.; Donovan, Benjamin D.; Miles, Drew M.; Tutt, James H.; Burwitz, Vadim; Menz, Benedikt; Hartner, Gisela D.; Smith, Randall K.; Cheimets, Peter; Hertz, Edward; Bookbinder, Jay A.; Günther, Ramses; Yanson, Alex; Vacanti, Giuseppe; Ackermann, Marcelo

2015-10-01

An x-ray spectrograph consisting of aligned, radially ruled off-plane reflection gratings and silicon pore optics (SPO) was tested at the Max Planck Institute for Extraterrestrial Physics PANTER x-ray test facility. SPO is a test module for the proposed Arcus mission, which will also feature aligned off-plane reflection gratings. This test is the first time two off-plane gratings were actively aligned to each other and with an SPO to produce an overlapped spectrum. We report the performance of the complete spectrograph utilizing the aligned gratings module and plans for future development.

Study of mutual occultation phenomena of the Galilean satellites at radio wavelengths

NASA Astrophysics Data System (ADS)

Pluchino, S.; Salerno, E.; Pupillo, G.; Schillirò, F.; Kraus, A.; Mack, K.-H.

2010-01-01

We present preliminary results for our study of mutual phenomena of the Galilean satellites performed at radio wavelengths with the Medicina and Noto antennas of the Istituto di Radioastronomia - INAF, and with the Effelsberg 100-m radio telescope of the Max-Planck-Institute for Radioastronomy, Bonn. Measurements of the radio flux density variation during the mutual occultations of Io by Europa and Ganymede were carried out during the PHEMU09 campaign at 22 GHz and 43 GHz. Flux density variations observed at radio wavelengths are consistent with the typical optical patterns measured when partial occultations occur.

Intercomparison of four regional climate models for the German State of Saxonia

NASA Astrophysics Data System (ADS)

Kreienkamp, F.; Spekat, A.; Enke, W.

2009-09-01

Results from four regional climate models which focus on Central Europe are presented: CCLM, the climate version of the German Weather Service's Local Model - REMO, the regional dynamic model from the Max Planck Institute for Meteorology in Hamburg - STAR, the statistical model developed at the PIK Potsdam Institute and WETTREG, the statistic-dynamic model developed by the company CEC Potsdam. For the area of the German State of Saxonia a host of properties and indicators were analyzed aiming to show the models' abilities to reconstruct the current climate and compare climate model scenarios. These include a group of thermal indicators, such as the number of ice, frost, summer and hot days, the number of tropical nights; then there are hydrometeorological indicators such as the exceedance of low and high precipitation thresholds; humidity, cloudiness and wind indicators complement the array. A selection of them showing similarities and differences of the models investigated will be presented.

Correlated Light-Matter Interactions in Cavity QED

NASA Astrophysics Data System (ADS)

Flick, Johannes; Pellegrini, Camilla; Ruggenthaler, Michael; Appel, Heiko; Tokatly, Ilya; Rubio, Angel

2015-03-01

In the last decade, time-dependent density functional theory (TDDFT) has been successfully applied to a large variety of problems, such as calculations of absorption spectra, excitation energies, or dynamics in strong laser fields. Recently, we have generalized TDDFT to also describe electron-photon systems (QED-TDDFT). Here, matter and light are treated on an equal quantized footing. In this work, we present the first numerical calculations in the framework of QED-TDDFT. We show exact solutions for fully quantized prototype systems consisting of atoms or molecules placed in optical high-Q cavities and coupled to quantized electromagnetic modes. We focus on the electron-photon exchange-correlation (xc) contribution by calculating exact Kohn-Sham potentials using fixed-point inversions and present the performance of the first approximated xc-potential based on an optimized effective potential (OEP) approach. Max Planck Institute for the Structure and Dynamics of Matter, Hamburg, and Fritz-Haber-Institut der MPG, Berlin

The emergence of Quantum Schools: Munich, Göttingen and Copenhagen as new centers of atomic theory

NASA Astrophysics Data System (ADS)

Eckert, M.

2001-01-01

The institutes of Arnold Sommerfeld in Munich, Niels Bohr in Copenhagen, and Max Born in Göttingen became the leading centers for the study of quantum theory in the first decades of the twentieth century. Although founded for a broader range of theoretical physics, the quantum became the major topic of research in Munich after the Bohr-Sommerfeld-model of the atom (1913-16). The heyday came in the 1920s, when Bohr's and Born's institutes started operation and became further attractive centers for ambitious theorists all over the world. The discovery of quantum mechanics (1925) should be regarded not only as the achievement of a few young geniuses (in particular Werner Heisenberg and Wolfgang Pauli) but also as the result of a collaborative effort emerging in the new social and intellectual environment of their teachers' schools in Munich, Göttingen and Copenhagen.

The blood from Auschwitz and the silence of the scholars.

PubMed

Müller-Hill, B

1999-01-01

The Kaiser Wilhelm Institute for Anthropology, Human Genetics and Eugenics in Berlin-Dahlem was the centre of scientific racism in Nazi Germany. Its bad history culminated in a research project to analyse the molecular basis of racial differences in the susceptibility to various infectious diseases such as tuberculosis. Josef Mengele, a former postdoc of the director of the institute, Otmar von Verschuer, collected blood samples and other material in Auschwitz from families and twins of Jews and Gypsies. The blood samples were analysed by Günther Hillmann in the Berlin laboratory of Nobel Prize winner Adolf Butenandt. Butenandt had just moved to Tübingen. The project was paid for by the Deutsche Forschungsgemeinschaft. Butenandt, Hillmann and von Verschuer made scientific careers in the Federal Republic. To the present day this past has not been acknowledged by the Max-Planck-Gesellschaft as part of its history.

[Effects of 100 Hz sinusoidal vibration on H reflex and M wave in rat soleus muscle following immobilization].

PubMed

Zhao, Xue-hong; Fan, Xiao-li; Song, Xin-ai; Shi, Lei

2011-09-01

To investigate the effects of 100 Hz sinusoidal vibration on H reflex and M wave in rat soleus muscle following immobilization. The immobilization of rat soleus muscle was induced as a disuse muscle model, and 100 Hz sinusoidal vibration was generated by a vibrator and applied to the immobilized soleus muscle, then the changes of H reflex and M wave in muscle were observed after 14 d. Compared to control, after 14 d of immobilization M(max) in soleus muscle decreased (P<0.01), stimulus threshold and S(max) increased (P<0.01); Hmax and H(max)/M(max) decreased (P<0.05, S(max) increased (P<0.05). Compared to immobilized soleus muscle, after 14 d of immobilization with 100 Hz sinusoidal vibration, the M(max) increased(P<0.01), stimulus threshold and S(Mmax) decreased (P<0.05), H(max) (P<0.01) increased and H(max)/M(max) increased (P<0.05). 100 Hz sinusoidal vibration plays a significant antagonist role against the changes in H reflex and M wave in rat soleus muscle following immobilization.

49 CFR 178.53 - Specification 4D welded steel cylinders for aircraft use.

Code of Federal Regulations, 2010 CFR

2010-10-01

... uniform and weldable quality must be used. Content may not exceed the following: Carbon, 0.25; phosphorus.... Phosphorus 0.04 max. Sulphur 0.05 max Silicon 0.15/0.35. Chromium 0.80/1.10. Molybdenum 0.15/0.25. Zirconium...(percent) 347(percent) Carbon (max) 0.08 0.08 0.08 0.08 Manganese (max) 2.00 2.00 2.00 2.00 Phosphorus (max...

49 CFR 178.53 - Specification 4D welded steel cylinders for aircraft use.

Code of Federal Regulations, 2011 CFR

2011-10-01

... weldable quality must be used. Content may not exceed the following: Carbon, 0.25; phosphorus, 0.045.... Phosphorus 0.04 max. Sulphur 0.05 max Silicon 0.15/0.35. Chromium 0.80/1.10. Molybdenum 0.15/0.25. Zirconium...(percent) 347(percent) Carbon (max) 0.08 0.08 0.08 0.08 Manganese (max) 2.00 2.00 2.00 2.00 Phosphorus (max...

Continuum kinetic modeling of the tokamak plasma edge

DOE PAGES

Dorf, M. A.; Dorr, M.; Rognlien, T.; ...

2016-03-10

In this study, the first 4D (axisymmetric) high-order continuum gyrokinetic transport simulations that span the magnetic separatrix of a tokamak are presented. The modeling is performed with the COGENT code, which is distinguished by fourth-order finite-volume discretization combined with mapped multiblock grid technology to handle the strong anisotropy of plasmatransport and the complex X-point divertor geometry with high accuracy. The calculations take into account the effects of fully nonlinear Fokker-Plank collisions, electrostatic potential variations, and anomalous radial transport. Topics discussed include: (a) ion orbit loss and the associated toroidal rotation and (b) edge plasma relaxation in the presence of anomalousmore » radial transport.« less

Diversity of Holocene life forms in fossil glacier ice

PubMed Central

Willerslev, Eske; Hansen, Anders J.; Christensen, Bent; Steffensen, Jørgen Peder; Arctander, Peter

1999-01-01

Studies of biotic remains of polar ice caps have been limited to morphological identification of plant pollen and spores. By using sensitive molecular techniques, we now demonstrate a much greater range of detectable organisms; from 2000- and 4000-year-old ice-core samples, we obtained and characterized 120 clones that represent at least 57 distinct taxa and reveal a diversity of fungi, plants, algae, and protists. The organisms derive from distant sources as well as from the local arctic environment. Our results suggest that additional taxa may soon be readily identified, providing a plank for future studies of deep ice cores and yielding valuable information about ancient communities and their change over time. PMID:10393940

Lingual–Alveolar Contact Pressure During Speech in Amyotrophic Lateral Sclerosis: Preliminary Findings

PubMed Central

Knollhoff, Stephanie; Barohn, Richard J.

2017-01-01

Purpose This preliminary study on lingual–alveolar contact pressures (LACP) in people with amyotrophic lateral sclerosis (ALS) had several aims: (a) to evaluate whether the protocol induced fatigue, (b) to compare LACP during speech (LACP-Sp) and during maximum isometric pressing (LACP-Max) in people with ALS (PALS) versus healthy controls, (c) to compare the percentage of LACP-Max utilized during speech (%Max) for PALS versus controls, and (d) to evaluate relationships between LACP-Sp and LACP-Max with word intelligibility. Method Thirteen PALS and 12 healthy volunteers produced /t, d, s, z, l, n/ sounds while LACP-Sp was recorded. LACP-Max was obtained before and after the speech protocol. Word intelligibility was obtained from auditory–perceptual judgments. Results LACP-Max values measured before and after completion of the speech protocol did not differ. LACP-Sp and LACP-Max were statistically lower in the ALS bulbar group compared with controls and PALS with only spinal symptoms. There was no statistical difference between groups for %Max. LACP-Sp and LACP-Max were correlated with word intelligibility. Conclusions It was feasible to obtain LACP-Sp measures without inducing fatigue. Reductions in LACP-Sp and LACP-Max for bulbar speakers might reflect tongue weakness. Although confirmation of results is needed, the data indicate that individuals with high word intelligibility maintained LACP-Sp at or above 2 kPa and LACP-Max at or above 50 kPa. PMID:28335033

Spatiotemporal variation of nitrate uptake kinetics within the maize (Zea mays L.) root system is associated with greater nitrate uptake and interactions with architectural phenes.

PubMed

York, Larry M; Silberbush, Moshe; Lynch, Jonathan P

2016-06-01

Increasing maize nitrogen acquisition efficiency is a major goal for the 21st century. Nitrate uptake kinetics (NUK) are defined by I max and K m, which denote the maximum uptake rate and the affinity of transporters, respectively. Because NUK have been studied predominantly at the molecular and whole-root system levels, little is known about the functional importance of NUK variation within root systems. A novel method was created to measure NUK of root segments that demonstrated variation in NUK among root classes (seminal, lateral, crown, and brace). I max varied among root class, plant age, and nitrate deprivation combinations, but was most affected by plant age, which increased I max, and nitrate deprivation time, which decreased I max K m was greatest for crown roots. The functional-structural simulation SimRoot was used for sensitivity analysis of plant growth to root segment I max and K m, as well as to test interactions of I max with root system architectural phenes. Simulated plant growth was more sensitive to I max than K m, and reached an asymptote near the maximum I max observed in the empirical studies. Increasing the I max of lateral roots had the largest effect on shoot growth. Additive effects of I max and architectural phenes on nitrate uptake were observed. Empirically, only lateral root tips aged 20 d operated at the maximum I max, and simulations demonstrated that increasing all seminal and lateral classes to this maximum rate could increase plant growth by as much as 26%. Therefore, optimizing I max for all maize root classes merits attention as a promising breeding goal. © The Author 2016. Published by Oxford University Press on behalf of the Society for Experimental Biology.

The use of plaque score measurements to assess changes in atherosclerotic plaque burden induced by lipid-lowering therapy over time: the METEOR study.

PubMed

Peters, Sanne A E; Dogan, Soner; Meijer, Rudy; Palmer, Mike K; Grobbee, Diederick E; Crouse, John R; O'Leary, Daniel H; Evans, Gregory W; Raichlen, Joel S; Bots, Michiel L

2011-01-01

To evaluate whether plaque scoring measurements are able to track changes in atherosclerotic plaque burden over time and to study whether this is affected by lipid-lowering therapy. Data used were from METEOR (Measuring Effects on Intima-Media Thickness: an Evaluation Of Rosuvastatin), a randomized controlled trial of rosuvastatin 40 mg among 984 low-risk patients with modest carotid intima-media thickening (CIMT). In this analysis, duplicate ultrasound images from 12 carotid sites were collected at the baseline and end of the study from 495 European patients and were evaluated for plaque presence and severity. Plaques were scored from near and far walls of the 12 sites (0= none; 1= minimal; 2= moderate; 3= severe) and plaque scores (PS) were combined into two summary measures for each examination. The MeanMaxPS is the mean over the 12 carotid sites of the maximum score at each site and the MaxMaxPS reflects the most severe lesion at any site. Baseline MeanMaxPS and MaxMaxPS were 0.31 (SD: 0.20) and 1.15 (SD: 0.51), respectively. Changes in MeanMaxPS and MaxMaxPS significantly differed between rosuvastatin and placebo (mean difference: -0.03 [SE: 0.01; p =0.016] and -0.09 [SE: 0.04; p =0.027], respectively). In contrast to rosuvastatin, which demonstrated no change from the baseline, placebo showed significant progression in MeanMaxPS and MaxMaxPS (p =0.002; both). The plaque-scoring method proved capable of assessing the change in atherosclerotic plaque burden over time and proved useful to evaluate lipid-lowering in asymptomatic individuals with a low risk of cardiovascular disease and subclinical atherosclerosis.

Influence of work-interval intensity and duration on time spent at a high percentage of VO2max during intermittent supramaximal exercise.

PubMed

Wakefield, Benjamin R; Glaister, Mark

2009-12-01

The purpose of this study was to examine the effect of work-interval duration (WID) and intensity on the time spent at, or above, 95% VO2max (T95 VO2max) during intermittent bouts of supramaximal exercise. Over a 5-week period, 7 physically active men with a mean (+/-SD) age, height, body mass, and VO2max of 22 +/- 5 years, 181.5 +/- 5.6 cm, 86.4 +/- 11.4 kg, and 51.5 +/- 1.5 ml.kg-1.min-1, respectively, attended 7 testing sessions. After completing a submaximal incremental test on a treadmill to identify individual oxygen uptake/running velocity relationships, subjects completed a maximal incremental test to exhaustion to VO2max and subsequently (from the aforementioned relationship) the minimum velocity required to elicit VO2max (vVO2max). In a random order, subjects then carried out 3 intermittent runs to exhaustion at both 105% and 115% vVO2max. Each test used a different WID (20 s, 25 s, or 30 s) interspersed with 20-second passive recovery periods. Results revealed no significant difference in T95 vVO2max for intermittent runs at 105% versus 115% vVO2max (p = 0.142). There was, however, a significant effect (p < 0.001) of WID on T95 VO2max, with WIDs of 30 seconds enabling more time relative to WIDs of 20 seconds (p = 0.018) and 25 seconds (p = 0.009). Moreover, there was an interaction between intensity and duration such that the effect of WID was magnified at the lower exercise intensity (p = 0.046). In conclusion, despite a number of limitations, the results of this investigation suggest that exercise intensities of approximately 105% vVO2max combined with WIDs greater than 25 seconds provide the best way of optimizing T95 VO2max when using fixed 20-second stationary rest periods.

Effect of a prior intermittent run at vVO2max on oxygen kinetics during an all-out severe run in humans.

PubMed

Billat, V L; Bocquet, V; Slawinski, J; Laffite, L; Demarle, A; Chassaing, P; Koralsztein, J P

2000-09-01

The purpose of this study was to examine the influence of prior intermittent running at VO2max on oxygen kinetics during a continuous severe intensity run and the time spent at VO2max. Eight long-distance runners performed three maximal tests on a synthetic track (400 m) whilst breathing through the COSMED K4 portable telemetric metabolic analyser: i) an incremental test which determined velocity at the lactate threshold (vLT), VO2max and velocity associated with VO2max (vVO2max), ii) a continuous severe intensity run at vLT+50% (vdelta50) of the difference between vLT and vVO2max (91.3+/-1.6% VO2max)preceded by a light continuous 20 minute run at 50% of vVO2max (light warm-up), iii) the same continuous severe intensity run at vdelta50 with a prior interval training exercise (hard warm-up) of repeated hard running bouts performed at 100% of vVO2max and light running at 50% of vVO2max (of 30 seconds each) performed until exhaustion (on average 19+/-5 min with 19+/-5 interval repetitions). This hard warm-up speeded the VO2 kinetics: the time constant was reduced by 45% (28+/-7 sec vs 51+/-37 sec) and the slow component of VO2 (deltaVO2 6-3 min) was deleted (-143+/-271 ml x min(-1) vs 291+/-153 ml x min(-1)). In conclusion, despite a significantly lower total run time at vdelta50 (6 min 19+/-0) min 17 vs 8 min 20+/-1 min 45, p=0.02) after the intermittent warm-up at VO2max, the time spent specifically at VO2max in the severe continuous run at vdelta50 was not significantly different.

Interval training at 95% and 100% of the velocity at VO2 max: effects on aerobic physiological indexes and running performance.

PubMed

Denadai, Benedito S; Ortiz, Marcelo J; Greco, Camila C; de Mello, Marco T

2006-12-01

The objective of this study was to analyze the effect of two different high-intensity interval training (HIT) programs on selected aerobic physiological indices and 1500 and 5000 m running performance in well-trained runners. The following tests were completed (n=17): (i) incremental treadmill test to determine maximal oxygen uptake (VO2 max), running velocity associated with VO2 max (vVO2 max), and the velocity corresponding to 3.5 mmol/L of blood lactate concentration (vOBLA); (ii) submaximal constant-intensity test to determine running economy (RE); and (iii) 1500 and 5000 m time trials on a 400 m track. Runners were then randomized into 95% vVO2 max or 100% vVO2 max groups, and undertook a 4 week training program consisting of 2 HIT sessions (performed at 95% or 100% vVO2 max, respectively) and 4 submaximal run sessions per week. Runners were retested on all parameters at the completion of the training program. The VO2 max values were not different after training for both groups. There was a significant increase in post-training vVO2 max, RE, and 1500 m running performance in the 100% vVO2 max group. The vOBLA and 5000 m running performance were significantly higher after the training period for both groups. We conclude that vOBLA and 5000 m running performance can be significantly improved in well-trained runners using a 4 week training program consisting of 2 HIT sessions (performed at 95% or 100% vVO2 max) and 4 submaximal run sessions per week. However, the improvement in vVO2 max, RE, and 1500 m running performance seems to be dependent on the HIT program at 100% vVO2 max.

The marginal fit of E.max Press and E.max CAD lithium disilicate restorations: A critical review.

PubMed

Mounajjed, Radek; M Layton, Danielle; Azar, Basel

2016-12-01

This critical review aimed to assess the vertical marginal gap that was present when E.max lithium disilicate-based restoration (Press and CAD) are fabricated in-vitro. Published articles reporting vertical marginal gap measurements of in-vitro restorations that had been fabricated from E.Max lithium disilicate were sought with an electronic search of MEDLINE (PubMed) and hand search of selected dental journals. The outcomes were reviewed qualitatively. The majority of studies that compared the marginal fit of E.max press and E.max CAD restorations, found that the E.max lithium disilicate restorations fabricated with the press technique had significantly smaller marginal gaps than those fabricated with CAD technique. This research indicates that E.max lithium disilicate restorations fabricated with the press technique have measurably smaller marginal gaps when compared with those fabricated with CAD techniques within in-vitro environments. The marginal gaps achieved by the restorations across all groups were within a clinically acceptable range.

History of EISCAT - Part 4: On the German contribution to the early years of EISCAT

NASA Astrophysics Data System (ADS)

Haerendel, Gerhard

2016-07-01

The decision of the Max Planck Society (MPG) to get involved in the establishment of an incoherent scatter radar in northern Europe was intimately linked to the future of the Max Planck Institute for Aeronomy (MPAe) in Katlenburg-Lindau. Delegates of the MPG played an important role in defining the rules for participation in EISCAT during the period from 1973 to 1975. The "technical" period from 1976 to 1981 was mainly devoted to the development of the UHF transmitter and the klystrons. The latter encountered great difficulties, causing substantial delays. During the same period the ionospheric heating facility was established by MPAe at Ramfjordmoen, Norway. The period following the inauguration in August 1981 saw a great number of changes in the leading personnel. In this context much attention had to be given to taxation rules. Besides continuing hardware problems with the UHF radar, severe problems arose with design and manufacturing of the VHF klystrons, requiring changes of the contractor. However, by fall of 1983 the UHF radar was able to reach the intended operational level. In 1984 important steps were made for archiving and for proper exploitation of the EISCAT data.

Endurance training and maximal oxygen consumption with ageing: Role of maximal cardiac output and oxygen extraction.

PubMed

Montero, David; Díaz-Cañestro, Candela

2016-05-01

The increase in maximal oxygen consumption (VO2max) with endurance training is associated with that of maximal cardiac output (Qmax), but not oxygen extraction, in young individuals. Whether such a relationship is altered with ageing remains unclear. Therefore, we sought systematically to review and determine the effect of endurance training on and the associations among VO2max, Qmax and arteriovenous oxygen difference at maximal exercise (Ca-vO2max) in healthy aged individuals. We conducted a systematic search of MEDLINE, Scopus and Web of Science, from their inceptions until May 2015 for articles assessing the effect of endurance training lasting 3 weeks or longer on VO2max and Qmax and/or Ca-vO2max in healthy middle-aged and/or older individuals (mean age ≥40 years). Meta-analyses were performed to determine the standardised mean difference (SMD) in VO2max, Qmax and Ca-vO2max between post and pre-training measurements. Subgroup and meta-regression analyses were used to evaluate the associations among SMDs and potential moderating factors. Sixteen studies were included after systematic review, comprising a total of 153 primarily untrained healthy middle-aged and older subjects (mean age 42-71 years). Endurance training programmes ranged from 8 to 52 weeks of duration. After data pooling, VO2max (SMD 0.89; P < 0.0001) and Qmax (SMD 0.61; P < 0.0001) were increased after endurance training; no heterogeneity among studies was detected. Ca-vO2max was only increased with endurance training interventions lasting more than 12 weeks (SMD 0.62; P = 0.001). In meta-regression, the SMD in Qmax was positively associated with the SMD in VO2max (B = 0.79, P = 0.04). The SMD in Ca-vO2max was not associated with the SMD in VO2max (B = 0.09, P = 0.84). The improvement in VO2max following endurance training is a linear function of Qmax, but not Ca-vO2max, through healthy ageing. © The European Society of Cardiology 2015.

General Corrosion Resistance Assessments of AA7085, AA7129, and Other High-Performance Aluminum Alloys for Department of Defense (DOD) Systems UsingLaboratory Based Accelerated Corrosion Methods and Electrochemistry

DTIC Science & Technology

2013-09-01

laboratory should play a role in the final design decision process. Integration factors such as conversion coatings , primers, topcoats, and their...Cyclic Accelerated Corrosion Analysis of Nonchromate Conversion Coatings on Aluminum Alloys 2024, 2219, 5083, and 7075 Using DoD Paint Systems; ARL...Titanium 0.08 0.10 max 0.10 max 0.15 max 0.08 max 0.05 max Zirconium 0.05 – 0.15 0.05 – 0.15 - 0.10 – 0.25 0.05 – 0.15 - Vanadium - - - - - 0.05 max

The influence of exercise duration at VO2 max on the off-transient pulmonary oxygen uptake phase during high intensity running activity.

PubMed

Billat, V L; Hamard, L; Koralsztein, J P

2002-12-01

The purpose of this study was to examine the influence of time run at maximal oxygen uptake (VO2 max) on the off-transient pulmonary oxygen uptake phase after supra-lactate threshold runs. We hypothesised: 1) that among the velocities eliciting VO2 max there is a velocity threshold from which there is a slow component in the VO2-off transient, and 2) that at this velocity the longer the duration of this time at VO2 max (associated with an accumulated oxygen kinetics since VO2 can not overlap VO2 max), the longer is the off-transient phase of oxygen uptake kinetics. Nine long-distance runners performed five maximal tests on a synthetic track (400 m) while breathing through the COSMED K4b2 portable, telemetric metabolic analyser: i) an incremental test which determined VO2 max, the minimal velocity associated with VO2 max (vVO2 max) and the velocity at the lactate threshold (vLT), ii) and in a random order, four supra-lactate threshold runs performed until exhaustion at vLT + 25, 50, 75 and 100% of the difference between vLT and vVO2 max (vdelta25, vdelta50, vdelta75, vdelta100). At vdelta25, vdelta50 (= 91.0 +/- 0.9% vVO2 max) and vdelta75, an asymmetry was found between the VO2 on (double exponential) and off-transient (mono exponential) phases. Only at vdelta75 there was at positive relationship between the time run at VO2 max (%tlimtot) and the VO2 recovery time constant (Z = 1.8, P = 0.05). In conclusion, this study showed that among the velocities eliciting VO2 max, vdelta75 is the velocity at which the longer the duration of the time at VO2 max, the longer is the off-transient phase of oxygen uptake kinetics. It may be possible that at vdelta50 there is not an accumulated oxygen deficit during the plateau of VO2 at VO2 max and that the duration of the time at VO2 max during the exhaustive runs at vdelta100, could be too short to induce an accumulating oxygen deficit affecting the oxygen recovery.

Studying the impact of different climate engineering techniques on ocean acidification with the Max Planck Institute Earth System Model

NASA Astrophysics Data System (ADS)

Gonzalez, M. F.; Ilyina, T.; Sonntag, S.

2016-02-01

In order to counterbalance the consequences of climate change, different climate engineering (CE) technologies have been suggested. Nonetheless, knowledge about their mitigation potential and side-effects remains sparse. Ocean alkalinization (OA) is an ocean-based carbon dioxide removal method, that aims at enhancing the natural process of weathering by which atmospheric CO2 is absorbed and stored in the ocean via chemical sequestration. Large-scale afforestation can also boost the uptake of CO2 by terrestrial biological systems and it is commonly considered as CE method. Stratospheric sulfur injection is a solar radiation management technique that has been proposed in order to enhance the Earth's albedo, mimicking the release of sulfur particles into the atmosphere during volcanic eruptions and the subsequent decrease in surface atmospheric temperatures. We explore the mitigation potential and side-effects of these CE technologies using the Max Planck Institute Earth System Model. Our scenarios are designed in order to test under what conditions it is possible to achieve a climate state that resembles the one of the representative concentration pathway (RCP) 4.5 under RCP8.5 greenhouse gas emissions. Direct and indirect effects of the OA method on the oceanic carbon cycle, differ strongly from those associated with afforestation and stratospheric sulfur injection. This is because they depend upon joint responses and synergies between different elements of the Earth system; thus, effects on the oceanic carbon cycle are not intuitively understood. Changes in the strength of the marine carbon sink, seawater pH and saturation state of carbonate minerals will be discussed. Additionally, collateral changes in marine biota and ocean biogeochemistry will be presented.

A Fast Numerical Method for Max-Convolution and the Application to Efficient Max-Product Inference in Bayesian Networks.

PubMed

Serang, Oliver

2015-08-01

Observations depending on sums of random variables are common throughout many fields; however, no efficient solution is currently known for performing max-product inference on these sums of general discrete distributions (max-product inference can be used to obtain maximum a posteriori estimates). The limiting step to max-product inference is the max-convolution problem (sometimes presented in log-transformed form and denoted as "infimal convolution," "min-convolution," or "convolution on the tropical semiring"), for which no O(k log(k)) method is currently known. Presented here is an O(k log(k)) numerical method for estimating the max-convolution of two nonnegative vectors (e.g., two probability mass functions), where k is the length of the larger vector. This numerical max-convolution method is then demonstrated by performing fast max-product inference on a convolution tree, a data structure for performing fast inference given information on the sum of n discrete random variables in O(nk log(nk)log(n)) steps (where each random variable has an arbitrary prior distribution on k contiguous possible states). The numerical max-convolution method can be applied to specialized classes of hidden Markov models to reduce the runtime of computing the Viterbi path from nk(2) to nk log(k), and has potential application to the all-pairs shortest paths problem.

Sequence-specific DNA binding by MYC/MAX to low-affinity non-E-box motifs.

PubMed

Allevato, Michael; Bolotin, Eugene; Grossman, Mark; Mane-Padros, Daniel; Sladek, Frances M; Martinez, Ernest

2017-01-01

The MYC oncoprotein regulates transcription of a large fraction of the genome as an obligatory heterodimer with the transcription factor MAX. The MYC:MAX heterodimer and MAX:MAX homodimer (hereafter MYC/MAX) bind Enhancer box (E-box) DNA elements (CANNTG) and have the greatest affinity for the canonical MYC E-box (CME) CACGTG. However, MYC:MAX also recognizes E-box variants and was reported to bind DNA in a "non-specific" fashion in vitro and in vivo. Here, in order to identify potential additional non-canonical binding sites for MYC/MAX, we employed high throughput in vitro protein-binding microarrays, along with electrophoretic mobility-shift assays and bioinformatic analyses of MYC-bound genomic loci in vivo. We identified all hexameric motifs preferentially bound by MYC/MAX in vitro, which include the low-affinity non-E-box sequence AACGTT, and found that the vast majority (87%) of MYC-bound genomic sites in a human B cell line contain at least one of the top 21 motifs bound by MYC:MAX in vitro. We further show that high MYC/MAX concentrations are needed for specific binding to the low-affinity sequence AACGTT in vitro and that elevated MYC levels in vivo more markedly increase the occupancy of AACGTT sites relative to CME sites, especially at distal intergenic and intragenic loci. Hence, MYC binds diverse DNA motifs with a broad range of affinities in a sequence-specific and dose-dependent manner, suggesting that MYC overexpression has more selective effects on the tumor transcriptome than previously thought.

Prediction of maximal oxygen uptake by bioelectrical impedance analysis in overweight adolescents.

PubMed

Roberts, M D; Drinkard, B; Ranzenhofer, L M; Salaita, C G; Sebring, N G; Brady, S M; Pinchbeck, C; Hoehl, J; Yanoff, L B; Savastano, D M; Han, J C; Yanovski, J A

2009-09-01

Maximal oxygen uptake (VO(2max)), the gold standard for measurement of cardiorespiratory fitness, is frequently difficult to assess in overweight individuals due to physical limitations. Reactance and resistance measures obtained from bioelectrical impedance analysis (BIA) have been suggested as easily obtainable predictors of cardiorespiratory fitness, but the accuracy with which ht(2)/Z can predict VO(2max) has not previously been examined in overweight adolescents. The impedance index was used as a predictor of VO(2max) in 87 overweight girls and 47 overweight boys ages 12 to 17 with mean BMI of 38.6 + or - 7.3 and 42.5 + or - 8.2 in girls and boys respectively. The Bland Altman procedure assessed agreement between predicted and actual VO(2max). Predicted VO(2max) was significantly correlated with measured VO(2max) (r(2)=0.48, P<0.0001). Using the Bland Altman procedure, there was significant magnitude bias (r(2)=0.10; P<0.002). The limits of agreement for predicted relative to actual VO(2max) were -589 to 574 mL O(2)/min. The impedance index was highly correlated with VO(2max) in overweight adolescents. However, using BIA data to predict maximal oxygen uptake over-predicted VO(2max) at low levels of oxygen consumption and under-predicted VO(2max) at high levels of oxygen consumption. This magnitude bias, along with the large limits of agreement of BIA-derived predicted VO(2max), limit its usefulness in the clinical setting for overweight adolescents.

System Level Applications of Adaptive Computing (SLAAC)

DTIC Science & Technology

2003-11-01

saved clock cycles, as the computation cycle time was directly proportional to the number of bitplanes in the image. The simulation was undertaken in...S-1][D -1] SK E W E R [k+K S-1][0] SK E W E R [k+K S-1][1] MinMax MinMax MinMax Min - IdxMin Max - IdxMax 0 Figure 3: PPI algorithm architeture ...parallel processing of data. The total throughput in these extended architectures is directly proportional to the amount of resources (CLB slices

Reference Curves for Field Tests of Musculoskeletal Fitness in U.S. Children and Adolescents: The 2012 NHANES National Youth Fitness Survey.

PubMed

Laurson, Kelly R; Saint-Maurice, Pedro F; Welk, Gregory J; Eisenmann, Joey C

2017-08-01

Laurson, KR, Saint-Maurice, PF, Welk, GJ, and Eisenmann, JC. Reference curves for field tests of musculoskeletal fitness in U.S. children and adolescents: The 2012 NHANES National Youth Fitness Survey. J Strength Cond Res 31(8): 2075-2082, 2017-The purpose of the study was to describe current levels of musculoskeletal fitness (MSF) in U.S. youth by creating nationally representative age-specific and sex-specific growth curves for handgrip strength (including relative and allometrically scaled handgrip), modified pull-ups, and the plank test. Participants in the National Youth Fitness Survey (n = 1,453) were tested on MSF, aerobic capacity (via submaximal treadmill test), and body composition (body mass index [BMI], waist circumference, and skinfolds). Using LMS regression, age-specific and sex-specific smoothed percentile curves of MSF were created and existing percentiles were used to assign age-specific and sex-specific z-scores for aerobic capacity and body composition. Correlation matrices were created to assess the relationships between z-scores on MSF, aerobic capacity, and body composition. At younger ages (3-10 years), boys scored higher than girls for handgrip strength and modified pull-ups, but not for the plank. By ages 13-15, differences between the boys and girls curves were more pronounced, with boys scoring higher on all tests. Correlations between tests of MSF and aerobic capacity were positive and low-to-moderate in strength. Correlations between tests of MSF and body composition were negative, excluding absolute handgrip strength, which was inversely related to other MSF tests and aerobic capacity but positively associated with body composition. The growth curves herein can be used as normative reference values or a starting point for creating health-related criterion reference standards for these tests. Comparisons with prior national surveys of physical fitness indicate that some components of MSF have likely decreased in the United States over time.

40 CFR 79.55 - Base fuel specifications.

Code of Federal Regulations, 2011 CFR

2011-07-01

... fuel's production or distribution and/or for the successful operation of the test vehicle/engine... the methanol, ethanol, methane, and propane base fuels in addition to any such additives included... chloride), wt%, max 0.0004 Copper, mg/L, max 0.07 Water, wt%, max 0.5 Sulfur, wt%, max 0.004 (f) Methane...

40 CFR 79.55 - Base fuel specifications.

Code of Federal Regulations, 2014 CFR

2014-07-01

... fuel's production or distribution and/or for the successful operation of the test vehicle/engine... the methanol, ethanol, methane, and propane base fuels in addition to any such additives included... chloride), wt%, max 0.0004 Copper, mg/L, max 0.07 Water, wt%, max 0.5 Sulfur, wt%, max 0.004 (f) Methane...

40 CFR 79.55 - Base fuel specifications.

Code of Federal Regulations, 2012 CFR

2012-07-01

... fuel's production or distribution and/or for the successful operation of the test vehicle/engine... the methanol, ethanol, methane, and propane base fuels in addition to any such additives included... chloride), wt%, max 0.0004 Copper, mg/L, max 0.07 Water, wt%, max 0.5 Sulfur, wt%, max 0.004 (f) Methane...

40 CFR 79.55 - Base fuel specifications.

Code of Federal Regulations, 2013 CFR

2013-07-01

... fuel's production or distribution and/or for the successful operation of the test vehicle/engine... the methanol, ethanol, methane, and propane base fuels in addition to any such additives included... chloride), wt%, max 0.0004 Copper, mg/L, max 0.07 Water, wt%, max 0.5 Sulfur, wt%, max 0.004 (f) Methane...

40 CFR 79.55 - Base fuel specifications.

Code of Federal Regulations, 2010 CFR

2010-07-01

... fuel's production or distribution and/or for the successful operation of the test vehicle/engine... the methanol, ethanol, methane, and propane base fuels in addition to any such additives included... chloride), wt%, max 0.0004 Copper, mg/L, max 0.07 Water, wt%, max 0.5 Sulfur, wt%, max 0.004 (f) Methane...

40 CFR 174.533 - Glycine max Herbicide-Resistant Acetolactate Synthase (GM-HRA) inert ingredient; exemption from...

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Glycine max Herbicide-Resistant... Glycine max Herbicide-Resistant Acetolactate Synthase (GM-HRA) inert ingredient; exemption from the requirement of a tolerance. Residues of Glycine max herbicide-resistant acetolactate synthase (GM-HRA) enzyme...

40 CFR 174.533 - Glycine max Herbicide-Resistant Acetolactate Synthase (GM-HRA) inert ingredient; exemption from...

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Glycine max Herbicide-Resistant... Glycine max Herbicide-Resistant Acetolactate Synthase (GM-HRA) inert ingredient; exemption from the requirement of a tolerance. Residues of Glycine max herbicide-resistant acetolactate synthase (GM-HRA) enzyme...

77 FR 20445 - eMax Worldwide, Inc.; Order of Suspension of Trading

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-04

... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] eMax Worldwide, Inc.; Order of Suspension of... the protection of investors require a suspension of trading in the securities of eMax Worldwide, Inc.... eMax Worldwide, Inc. has failed to make periodic filings with the Commission and has more than 300...

MAX mutations status in Swedish patients with pheochromocytoma and paraganglioma tumours.

PubMed

Crona, Joakim; Maharjan, Rajani; Delgado Verdugo, Alberto; Stålberg, Peter; Granberg, Dan; Hellman, Per; Björklund, Peyman

2014-03-01

Pheochromocytoma (PCC) and Paraganglioma are rare tumours originating from neuroendocrine cells. Up to 60% of cases have either germline or somatic mutation in one of eleven described susceptibility loci, SDHA, SDHB, SDHC, SDHD, SDHAF2, VHL, EPAS1, RET, NF1, TMEM127 and MYC associated factor-X (MAX). Recently, germline mutations in MAX were found to confer susceptibility to PCC and paraganglioma (PGL). A subsequent multicentre study found about 1% of PCCs and PGLs to have germline or somatic mutations in MAX. However, there has been no study investigating the frequency of MAX mutations in a Scandinavian cohort. We analysed tumour specimens from 63 patients with PCC and PGL treated at Uppsala University hospital, Sweden, for re-sequencing of MAX using automated Sanger sequencing. Our results show that 0% (0/63) of tumours had mutations in MAX. Allele frequencies of known single nucleotide polymorphisms rs4902359, rs45440292, rs1957948 and rs1957949 corresponded to those available in the Single Nucleotide Polymorphism Database. We conclude that MAX mutations remain unusual events and targeted genetic screening should be considered after more common genetic events have been excluded.

[Parameter optimization of BEPS model based on the flux data of the temperate deciduous broad-leaved forest in Northeast China.

PubMed

Lu, Wei; Fan, Wen Yi; Tian, Tian

2016-05-01

Keeping other parameters as empirical constants, different numerical combinations of the main photosynthetic parameters V c max and J max were conducted to estimate daily GPP by using the iteration method in this paper. To optimize V c max and J max in BEPSHourly model at hourly time steps, simulated daily GPP using different numerical combinations of the parameters were compared with the flux tower data obtained from the temperate deciduous broad-leaved forest of the Maoershan Forest Farm in Northeast China. Comparing the simulated daily GPP with the observed flux data in 2011, the results showed that optimal V c max and J max for the deciduous broad-leaved forest in Northeast China were 41.1 μmol·m -2 ·s -1 and 82.8 μmol·m -2 ·s -1 respectively with the minimal RMSE and the maximum R 2 of 1.10 g C·m -2 ·d -1 and 0.95. After V c max and J max optimization, BEPSHourly model simulated the seasonal variation of GPP better.

Pathological and Genetic Characterization of Bilateral Adrenomedullary Hyperplasia in a Patient with Germline MAX Mutation.

PubMed

Romanet, Pauline; Guerin, Carole; Pedini, Pascal; Essamet, Wassim; Castinetti, Frédéric; Sebag, Fréderic; Roche, Philippe; Cascon, Alberto; Tischler, Arthur S; Pacak, Karel; Barlier, Anne; Taïeb, David

2017-12-01

In recent years, familial pheochromocytoma (PHEO) with germline mutations in the MAX (MYC associated factor X) gene has been reported in a few cases. Here, we investigated a 25-year-old patient with multiple PHEOs associated with a non-sense germline MAX mutation. Preoperative 18 F-FDOPA PET/CT revealed bilateral adrenal involvement with multiple tumors. In addition, both adrenal glands were found to have diffuse or nodular adrenal medullary hyperplasia (AMH), a histopathological feature previously described as a precursor of MEN2- and SDHB-related PHEOs but not MAX. After bilateral adrenalectomy, different paraffin-embedded and frozen samples were analyzed for allelic imbalances of the MAX gene using allelic quantification by pyrosequencing. The expression of the protein MAX was studied by immunohistochemistry. All PHEOs but also nodular AMH exhibited a loss of the normal allele. By contrast, the diffuse AMH did not show loss-of-heterozygosity. Nevertheless, immunohistochemistry demonstrated loss of protein MAX expression in all samples including diffuse hyperplasia, suggesting a causative role of MAX mutation for both PHEOs and AMH. The present case shows that both nodular and diffuse AMH belongs to the spectrum of MAX-related disease. These data support the possible continuum between nodular AMH and PHEO, expanding the qualification of micro-PHEO to nodular AMH.

Science data archives of Indian Space Research Organisation (ISRO): Chandrayaan-1

NASA Astrophysics Data System (ADS)

Gopala Krishna, Barla; Singh Nain, Jagjeet; Moorthi, Manthira

The Indian Space Research Organisation (ISRO) has started a new initiative to launch dedicated scientific satellites earmarked for planetary exploration, astronomical observation and space sciences. The Chandrayaan-1 mission to Moon is one of the approved missions of this new initiative. The basic objective of the Chandrayaan-1 mission, scheduled for launch in mid 2008, is photoselenological and chemical mapping of the Moon with better spatial and spectral resolution. Consistent with this scientific objective, the following baseline payloads are included in this mission: (i) Terrain mapping stereo camera (TMC) with 20 km swath (400-900 nm band) for 3D imaging of lunar surface at a spatial resolution of 5m. (ii) Hyper Spectral Imager in the 400- 920 nm band with 64 channels and spatial resolution of 80m (20 km swath) for mineralogical mapping. (iii) High-energy X-ray (30-270 keV) spectrometer having a footprint of 40 km for study of volatile transport on Moon and (iv) Laser ranging instrument with vertical resolution of 5m. ISRO offered opportunity to the international scientific community to participate in Chandrayaan- 1 mission and six payloads that complement the basic objective of the Chandrayaan-1 mission have been selected and included in this mission viz., (i) a miniature imaging radar instrument (Mini-SAR) from APL, NASA to look for presence of ice in the polar region, (ii) a near infrared spectrometer (SIR-2) from Max Plank Institute, Germany, (iii) a Moon Mineralogy Mapper (M3) from JPL, NASA for mineralogical mapping in the infra-red regions (0.7 - 3.0 micron), (iv) a sub-keV atom reflecting analyzer (SARA) from Sweden, India, Switzerland and Japan for detection of low energy neutral atoms emanated from the lunar surface,(v) a radiation dose monitor (RADOM) from Bulgaria for monitoring energetic particle flux in the lunar environment and (vi) a collimated low energy (1-10keV) X-ray spectrometer (C1XS) with a field of view of 20 km for chemical mapping of the lunar surface from RAL, UK. Science data from the Chandrayaan-1 instruments is planned to be archived by combined efforts from all the instrument and Payload Operations Centre (POC) teams, the Indian Space Science Data Centre (ISSDC), the Chandrayaan-1 Spacecraft Control Centre (SCC). Chandrayaan-1 Science Data Archive (CSDA) is planned at ISSDC is the primary data center for the payload data archives of Indian Space Science Missions. This data center is responsible for the Ingest, Archive, and Dissemination of the payload and related ancillary data for Space Science missions like Chandrayaan-1. The archiving process includes the design, generation, validation and transfer of the data archive. The archive will include raw and reduced data, calibration data, auxiliary data, higher-level derived data products, documentation and software. The CSDA will make use of the well-proven archive standards of the Planetary Data System (PDS) and planned to follow IPDA guidelines. This is to comply with the global standards for long term preservation of the data, maintain their usability and facilitate scientific community with the high quality data for their analysis. The primary users of this facility will be the principal investigators of the science payloads initially till the lock-in period. After this, the data will be made accessible to scientists from other institutions and also to the general public. The raw payload data received through the data reception stations is further processed to generate Level-0 and Level-1 data products, which are stored in the CSDA for subsequent dissemination. According to the well documented Chandrayaan-1 archive plan agreed by the experiment teams, the data collection period is decided to be six months. The first data delivery to long term archive of CSDA after peer review is expected to be eighteen months after launch. At present, Experimenter to Archive ICDs of the instrument data are under the process of review.

Chandra Detects Halo Of Hot Gas Around Milky Way-Like Galaxy

NASA Astrophysics Data System (ADS)

2001-07-01

The first unambiguous evidence for a giant halo of hot gas around a nearby, spiral galaxy much like our own Milky Way was found by astronomers using NASA's Chandra X-ray Observatory. This discovery may lead to a better understanding of our own Galaxy, as well the structure and evolution of galaxies in general. A team of astronomers, led by Professor Daniel Wang of the University of Massachusetts, Amherst, observed NGC 4631, a spiral galaxy approximately 25 million light years from Earth with both Chandra and NASA's Hubble Space Telescope. While previous X-ray satellites have detected extended X-ray emission from this and other spiral galaxies, because of Chandra's exceptional resolution this is the first time that astronomers were able to separate the individual X-ray sources from the diffuse halo. Chandra found the diffuse halo of X-ray gas to be radiating at a temperature of almost 3 million degrees and extending some 25,000 light years from the galactic plane. "Scientists have debated for over 40 years whether the Milky Way has an extended corona, or halo, of hot gas," said Wang, lead author of the paper which appeared this month in The Astrophysical Journal Letters. "Of course since we are within the Milky Way, we can't get outside and take a picture. However, by studying similar galaxies like NGC 4631, we can get an idea of what's going on within our own Galaxy." The Chandra image reveals a halo of hot gas that extends for approximately 25,000 light years above the disk of the galaxy. One important feature of the X-ray emission from NGC 4631 is that it closely resembles the overall size and shape seen in the radio emission from the galaxy. This indicates that there may be a close connection between the outflows of hot gas, seen in X-rays, and the galaxy's magnetic field, revealed by radio emission. The Hubble image of NGC 4631 shows filamentary, loop-like structures enclosing enhanced X-ray-emitting gas and emanating from regions of recent star formation in the galaxy's disk. These data clearly show the hot gas is heated by clusters of massive stars and is now expanding into the halo of the galaxy. NGC 4631 X-ray: NASA/CXC/UMass/D.Wang et al. UV: NASA/GSFC/UIT "What we see in NGC 4631 can be thought of as the bursting flames of a gigantic cosmic camp fire," said Wang. "Using Chandra and Hubble together, we really get a complete story of what is happening in this galaxy." NGC 4631 is a galaxy that has high amounts of star formation, possibly triggered by interaction with neighboring galaxies. Such star formation might have created the conditions necessary to heat the gas seen by Chandra, as vast amounts of energy are released from supernovas and massive stars in star-forming regions - enough to lift the gas out of the plane of the galaxy. These new results provide important clues about the cycling of energy and mass in a galaxy like our own Milky Way and about the evolutionary history of galaxies, which are thought to be more active in star formation in the past than at the present. Other members of the research team include: Stefan Immler, University of Massachusetts; Rene Walterbos, New Mexico State University; James Lauroesch, Northwestern University, Evanston, IL, and Dieter Breitschwerdt, Max Plank Institute, Germany. Chandra observed NGC 4631 with its Advanced CCD Imaging Spectrometer (ACIS) instrument, which was developed for NASA by Pennsylvania State University, University Park, and Massachusetts Institute of Technology, Cambridge. NASA's Marshall Space Flight Center in Huntsville, AL, manages the Chandra program, and TRW, Inc., Redondo Beach, CA, is the prime contractor for the spacecraft. The Smithsonian's Chandra X-ray Center controls science and flight operations from Cambridge, MA.

The correlation between running economy and maximal oxygen uptake: cross-sectional and longitudinal relationships in highly trained distance runners.

PubMed

Shaw, Andrew J; Ingham, Stephen A; Atkinson, Greg; Folland, Jonathan P

2015-01-01

A positive relationship between running economy and maximal oxygen uptake (V̇O2max) has been postulated in trained athletes, but previous evidence is equivocal and could have been confounded by statistical artefacts. Whether this relationship is preserved in response to running training (changes in running economy and V̇O2max) has yet to be explored. This study examined the relationships of (i) running economy and V̇O2max between runners, and (ii) the changes in running economy and V̇O2max that occur within runners in response to habitual training. 168 trained distance runners (males, n = 98, V̇O2max 73.0 ± 6.3 mL∙kg-1∙min-1; females, n = 70, V̇O2max 65.2 ± 5.9 mL kg-1∙min-1) performed a discontinuous submaximal running test to determine running economy (kcal∙km-1). A continuous incremental treadmill running test to volitional exhaustion was used to determine V̇O2max 54 participants (males, n = 27; females, n = 27) also completed at least one follow up assessment. Partial correlation analysis revealed small positive relationships between running economy and V̇O2max (males r = 0.26, females r = 0.25; P<0.006), in addition to moderate positive relationships between the changes in running economy and V̇O2max in response to habitual training (r = 0.35; P<0.001). In conclusion, the current investigation demonstrates that only a small to moderate relationship exists between running economy and V̇O2max in highly trained distance runners. With >85% of the variance in these parameters unexplained by this relationship, these findings reaffirm that running economy and V̇O2max are primarily determined independently.

Modification of Fox protocol for prediction of maximum oxygen uptake in male university students.

PubMed

Bandyopadhyay, Amit; Pal, Sangita

2015-01-01

Direct estimation of VO₂max involves labourious, exhaustive, hazardous, time consuming and expensive experimental protocols. Hence, application of various indirect protocols for prediction of VO₂max has become popular, subject to proper population-specific standardisation of the indirect protocol. Application of Fox (1973) protocol in male sedentary university students of Kolkata, India led to premature fatigue in their leg muscles that hindered the muscular activity leading to inability in completing the exercise. The present study was aimed at modifying and validating the Fox (1973) protocol with a convenient workload of 110 W (i.e., modified Fox test or MFT) in the said population. Ninety (90) sedentary male students were recruited by simple random sampling from the University of Calcutta, India and they were randomly assigned into study group (n=60) and confirmatory group (n=30). VO₂max was directly estimated by Scholander micro-gas analysis after incremental bicycle exercise. Predicted VO₂max (PVO₂max) was computed from MFT by using the submaximal heart rate (HR(sub). In the Study Group VO₂max (2216.63 ± 316.77 mL.min⁻¹ was significantly different (P< 0.001) from PVO₂max (3131.73 ± 234.32 mL.min⁻¹ measured by using the equation of Fox (1973). Simple and multiple regression equations have been computed for prediction of VO₂max from HR(sub) and physical parameters. Application of these norms in the confirmatory group depicted insignificant difference between VO₂max and PVO₂max with substantially small limits of agreement and lower values of SEE. The modified regression norms are therefore recommended for use in MFT for accurate assessment of VO₂max in the studied population.

The use and misuse of V(c,max) in Earth System Models.

PubMed

Rogers, Alistair

2014-02-01

Earth System Models (ESMs) aim to project global change. Central to this aim is the need to accurately model global carbon fluxes. Photosynthetic carbon dioxide assimilation by the terrestrial biosphere is the largest of these fluxes, and in many ESMs is represented by the Farquhar, von Caemmerer and Berry (FvCB) model of photosynthesis. The maximum rate of carboxylation by the enzyme Rubisco, commonly termed V c,max, is a key parameter in the FvCB model. This study investigated the derivation of the values of V c,max used to represent different plant functional types (PFTs) in ESMs. Four methods for estimating V c,max were identified; (1) an empirical or (2) mechanistic relationship was used to relate V c,max to leaf N content, (3) V c,max was estimated using an approach based on the optimization of photosynthesis and respiration or (4) calibration of a user-defined V c,max to obtain a target model output. Despite representing the same PFTs, the land model components of ESMs were parameterized with a wide range of values for V c,max (-46 to +77% of the PFT mean). In many cases, parameterization was based on limited data sets and poorly defined coefficients that were used to adjust model parameters and set PFT-specific values for V c,max. Examination of the models that linked leaf N mechanistically to V c,max identified potential changes to fixed parameters that collectively would decrease V c,max by 31% in C3 plants and 11% in C4 plants. Plant trait data bases are now available that offer an excellent opportunity for models to update PFT-specific parameters used to estimate V c,max. However, data for parameterizing some PFTs, particularly those in the Tropics and the Arctic are either highly variable or largely absent.

Biochemical interactions between Glycine max L. silicon dioxide (SiO2) and plant growth-promoting bacteria (PGPR) for improving phytoremediation of soil contaminated with fenamiphos and its degradation products.

PubMed

Romeh, Ahmed Ali; Hendawi, Mohamed Yousef

2017-10-01

Fenamiphos is a systematic nematicide-insecticide used extensively for the control of soil nematodes. Fenamiphos and oxidation products have been known to induce water pollution, soil pollution and ecotoxicological effects on aquatic organisms, as well as heath issues. This contaminant can be removed by phytoremediation. Herein, we tested several strategies to improve the effectiveness of this technology. A combination of G. max plus Pseudomonas fluorescens was more efficient than G. max plus Serratia marcescens or G. max alone in degrading fenamiphos to other metabolites. Three major metabolites, namely fenamiphos sulfoxide (FSO), fenamiphos sulfone (FSO 2 ) and fenamiphos phenol (F-phenol), were detected in roots and leaves in which G. max amended with P. fluorescens or amended with S. marcescens produced a significant accumulation of FSO and FSO 2 with higher amounts than for G. max alone. Leaf concentrations of FSO were always higher than in the roots, while FSO 2 accumulated significantly more in G. max roots than in G. max leaves. In soil treated with fenamiphos, G. max roots and leaves alone, and in combined effects of plant and microorganisms, resulted in the disappearance of fenamiphos and the appearance of F-SO, F-SO 2 and F-phenol, which in turn caused toxic stress in G. max and the resulting production of reactive oxygen species such as H 2 O 2 with higher content and an increase in antioxidant GPX activity. Although a batch equilibrium technique showed that use of SiO 2 resulted in the efficient removal of fenamiphos when compared with other treatments for removing adsorbed fenamiphos from soil, a fewer amount of fenamiphos was removed by G. max L. with SiO 2 . H 2 O 2 content and GPX activity increased in G. max under fenamiphos treatment and its degradation products, while amended G. max with SiO 2 or Argal led to a decrease in GPX activity and H 2 O 2 content. Copyright © 2017 Elsevier B.V. All rights reserved.

Effects of strict prolonged bed rest on cardiorespiratory fitness: systematic review and meta-analysis.

PubMed

Ried-Larsen, Mathias; Aarts, Hugo M; Joyner, Michael J

2017-10-01

The aim of this systematic review and meta-analysis [International Prospective Register of Systematic Reviews (PROSPERO) CRD42017055619] was to assess the effects of strict prolonged bed rest (without countermeasures) on maximal oxygen uptake (V̇o 2max ) and to explore sources of variation therein. Since 1949, 80 studies with a total of 949 participants (>90% men) have been published with data on strict bed rest and V̇o 2max The studies were conducted mainly in young participants [median age (interquartile range) 24.5 (22.4-34.0) yr]. The duration of bed rest ranged from 1 to 90 days. V̇o 2max declined linearly across bed rest duration. No statistical difference in the decline among studies reporting V̇o 2max as l/min (-0.3% per day) compared with studies reporting V̇o 2max normalized to body weight (ml·kg -1 ·min -1 ; -0.43% per day) was observed. Although both total body weight and lean body mass declined in response to bed rest, we did not see any associations with the decline in V̇o 2max However, 15-26% of the variation in the decline in V̇o 2max was explained by the pre-bed-rest V̇o 2max levels, independent of the duration of bed rest (i.e., higher pre-bed-rest V̇o 2max levels were associated with larger declines in V̇o 2max ). Furthermore, the systematic review revealed a gap in the knowledge about the cardiovascular response to extreme physical inactivity, particularly in older subjects and women of any age group. In addition to its relevance to spaceflight, this lack of data has significant translational implications because younger women sometimes undergo prolonged periods of bed rest associated with the complications of pregnancy and the incidence of hospitalization including prolonged periods of bed rest increases with age. NEW & NOTEWORTHY Large interindividual responses of maximal oxygen uptake (V̇o 2max ) to aerobic exercise training exist. However, less is known about the variability in the response of V̇o 2max to prolonged bed rest. This systematic review and meta-analysis showed that pre-bed-rest V̇o 2max values were inversely associated with the change in V̇o 2max independent of the duration of bed rest. Moreover, we identified a large knowledge gap about the causes of decline in V̇o 2max , particularly in postmenopausal women, which may have clinical implications. Copyright © 2017 the American Physiological Society.

Changes in Oxygen Consumption and Heart Rate After Acute Myocardial Infarction During 6-Month Follow-up.

PubMed

Choe, Yuri; Han, Jae-Young; Choi, In-Sung; Park, Hyeng-Kyu

2018-06-01

Exercise intensity is a particularly important determinant of physiological responses to exercise training in patients with acute myocardial infarction. Heart rate (HR) is commonly used as a practical way of prescribing and monitoring exercise as specific intensities based on a linear relationship between the percentage of maximum HR (%HR max ) and the percentage of maximum oxygen consumption (%VO 2max ) regardless of age, gender, or exercise mode. To examine the change in variability in the correlation between %HR max and %VO 2max after acute myocardial infarction. Retrospective study. Regional cardio-cerebrovascular center at a tertiary hospital. A total of 66 patients were enrolled who were referred for cardiac rehabilitation (CR) after percutaneous intervention, and who had reached stage 3 of the modified Bruce Protocol (mBP) on an exercise tolerance test (ETT). There were 54 men and 12 women with an average age of 56.7 ± 9.48 years, ejection fraction (EF) of 56.4% ± 8.89%, and body mass index (BMI) of 24.73 ± 2.86 kg/m 2 . All patients participated in a 4-week outpatient CR program and underwent ETT with a gas analyzer to determine maximal heart rate and maximal oxygen consumption before CR and 1 month, 3 months, and 6 months after CR. VO 2max and HR max were defined as the highest values attained during the ETT. The HR and VO 2 values at each stage of the mBP were expressed as percentages of their maximum. %HR max and %VO 2max were calculated at each stage of the mBP. The maximum METs and VO 2max significantly improved at 1 month after CR, but not significantly at 3 and 6 months after CR. The correlation between VO 2max and HR max progressively changed in a favorable manner during CR. The relationship between %HR max and %VO 2max indicated a coefficient of variation before and 1, 3, and 6 months after of 0.800, 0.826, 0.832, and 0.880, respectively. This study showed that the %HR max correlates better with the %VO 2max in the late-stage post-AMI than in the initial stage. We should therefore set and monitor the exercise intensity using maximal oxygen consumption in the early stage of exercise training after onset of acute myocardial infarction. IV. Copyright © 2018 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

Blood flow regulation and oxygen uptake during high-intensity forearm exercise.

PubMed

Nyberg, S K; Berg, O K; Helgerud, J; Wang, E

2017-04-01

The vascular strain is very high during heavy handgrip exercise, but the intensity and kinetics to reach peak blood flow, and peak oxygen uptake, are uncertain. We included 9 young (25 ± 2 yr) healthy males to evaluate blood flow and oxygen uptake responses during continuous dynamic handgrip exercise with increasing intensity. Blood flow was measured using Doppler-ultrasound, and venous blood was drawn from a deep forearm vein to determine arteriovenous oxygen difference (a-vO 2diff ) during 6-min bouts of 60, 80, and 100% of maximal work rate (WR max ), respectively. Blood flow and oxygen uptake increased ( P < 0.05) from 60%WR max [557 ± 177(SD) ml/min; 56.0 ± 21.6 ml/min] to 80%WR max (679 ± 190 ml/min; 70.6 ± 24.8 ml/min), but no change was seen from 80%WR max to 100%WR max Blood velocity (49.5 ± 11.5 to 58.1 ± 11.6 cm/s) and brachial diameter (0.49 ± 0.05 to 0.50 ± 0.06 cm) showed concomitant increases ( P < 0.05) with blood flow from 60% to 80%WR max, whereas no differences were observed in a-vO 2diff Shear rate also increased ( P < 0.05) from 60% (822 ± 196 s -1 ) to 80% (951 ± 234 s -1 ) of WR max The mean response time (MRT) was slower ( P < 0.05) for blood flow (60%WR max 50 ± 22 s; 80%WR max 51 ± 20 s; 100%WR max 51 ± 23 s) than a-vO 2diff (60%WR max 29 ± 9 s; 80%WR max 29 ± 5 s; 100%WR max 20 ± 5 s), but not different from oxygen uptake (60%WR max 44 ± 25 s; 80%WR max 43 ± 14 s; 100%WR max 41 ± 32 s). No differences were observed in MRT for blood flow or oxygen uptake with increased exercise intensity. In conclusion, when approaching maximal intensity, oxygen uptake appeared to reach a critical level at ~80% of WR max and be regulated by blood flow. This implies that high, but not maximal, exercise intensity may be an optimal stimulus for shear stress-induced small muscle mass training adaptations. NEW & NOTEWORTHY This study evaluated blood flow regulation and oxygen uptake during small muscle mass forearm exercise with high to maximal intensity. Despite utilizing only a fraction of cardiac output, blood flow reached a plateau at 80% of maximal work rate and regulated peak oxygen uptake. Furthermore, the results revealed that muscle contractions dictated bulk oxygen delivery and yielded three times higher peak blood flow in the relaxation phase compared with mean values. Copyright © 2017 the American Physiological Society.

Verification, Validation and Accreditation using AADL

DTIC Science & Technology

2011-05-03

component h component, c r2 socsr hhh  max. height (surface relative), hsr r1 pwbsra thh  max. height (absolute), ha pwb pwb t c0. Context-Specific...5512 digital oscillatorABC_9230 Warning Module PWB component component, c r2 hhh max. height (surface relative), hsr r1 pwbsra thh  max. height

Leap of Faith: An Interview with Max Velthuijs

ERIC Educational Resources Information Center

de Rijke, Victoria; Hollands, Howard

2006-01-01

The now late great Max Velthuijs was filmed in April 2004 discussing his work with Victoria de Rijke and Howard Hollands, who began the interview expecting Max to be working under certain artistic and cultural influences, none of which seemed to be the case! Max describes what brought him home to Andersen Press, the freedom of children's…

Complex, Precision Cast Columbium Alloy Gas Turbine Engine Nozzles Coated to Resist Oxidation.

DTIC Science & Technology

1980-04-01

Microstructures of Sprayed Specimens 64 Table 19 NS-4 Coated C129Y Alloy Specimens Weight Bisque Weight Sintered Weight Silicided Weight Pre-Oxidized...choice of another alloy , while perhaps assisting in the foundry process , would not have yielded a mechanical property data base with advantage over...Mo 250 ppm max; Fe 30 ppm max; Al , Ca, C, Si, Cr, Ni, Cu , Mn, Mg and Sn 10 ppm max each). Molybdenum វim powder (02 2000 ppm max; W 250 ppm max; Fe

77 FR 32513 - Hot-Rolled Flat-Rolled Carbon-Quality Steel Products From the Russian Federation; Preliminary...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-01

..., physical and mechanical specifications: C Mn P S Si Cr Cu Ni 0.10-0.14% 0.90% Max 0.025% Max 0.005% Max 0... meets the following chemical, physical and mechanical specifications: C Mn P S Si Cr Cu Ni 0.10-0.16% 0... specifications: C Mn P S Si Cr Cu Ni 0.10-0.14% 1.30-1.80% 0.025% Max 0.005% Max 0.30-0.50% 0.50-0.70% 0.20-0.40...

Asymptotics in Time, Temperature and Size for Optimization by Simulated Annealing: Theory, Practice and Applications

DTIC Science & Technology

1990-01-19

following theorem from the Perron - Frobenius theory of nonnegative matrices. Theorem 2.2 : [1] Consider an irreducible Markov chain with transition...us suppose to the contrary that both expressions are nonnegative . Then max ,01v,,= max /3,1v,,> max 3OV,,= max /3,0V max i,01v,,, -A.,. A’ ,, A.i. A...induction. For k 1, from (20) we see that (22) /3, 8 ,, _-30,A V(). Clearly, the left-hand side of (22) is nonnegative , implying that the right-hand

Improvements of ModalMax High-Fidelity Piezoelectric Audio Device

NASA Technical Reports Server (NTRS)

Woodard, Stanley E.

2005-01-01

ModalMax audio speakers have been enhanced by innovative means of tailoring the vibration response of thin piezoelectric plates to produce a high-fidelity audio response. The ModalMax audio speakers are 1 mm in thickness. The device completely supplants the need to have a separate driver and speaker cone. ModalMax speakers can perform the same applications of cone speakers, but unlike cone speakers, ModalMax speakers can function in harsh environments such as high humidity or extreme wetness. New design features allow the speakers to be completely submersed in salt water, making them well suited for maritime applications. The sound produced from the ModalMax audio speakers has sound spatial resolution that is readily discernable for headset users.

A comparison of thunderstorm reflectivities measured at the VHF and UHF

NASA Technical Reports Server (NTRS)

Larsen, M. F.; Rottger, J.

1986-01-01

Observations of thunderstorms made with two radars operating at different wavelengths of 70 cm and 5.67 m are compared. The first set of observations was made with the UHF radar at the Arecibo Observatory in Puerto Rico, and the second set was made with the Max-Planck-Institut fur Aeronomie VHF radar in the Harz Mountains in West Germany. Both sets of observations show large echo strengths in the convective region above the -10 C isothem. At UHF, there appears to be a contribution from both the precipitation echoes and the normal echoes due to scatter from turbulent variations in the refractive index.

Few-Body Techniques Using Momentum Space for Bound and Continuum States

NASA Astrophysics Data System (ADS)

Yamashita, M. T.; Rosa, D. S.; Sandoval, J. H.

2018-05-01

This article is based on the notes (arxiv:1710.11228) written for a set of three lectures given in a school at the Max Planck Institute for the Physics of Complex Systems in October/2017 before the workshop "Critical Stability of Quantum Few-Body Systems". The last part of the article includes the specific topic presented in the workshop related to the dimensional effects in three-body systems. These notes are primarily dedicated to the students and are only a tentative to show a technique, among many others, to solve problems in a very rich area of the contemporary physics—the Few-Body Physics.

Otto Hahn: Responsibility and Repression

NASA Astrophysics Data System (ADS)

Walker, Mark

2006-05-01

The role that Otto Hahn (1879 1968) played in the discovery of nuclear fission and whether Lise Meitner (1878 1968) should have shared the Nobel Prize for that discovery have been subjects of earlier studies, but there is more to the story. I examine what Hahn and the scientists in his Kaiser Wilhelm Institute for Chemistry in Berlin-Dahlem did during the Third Reich, in particular, the significant contributions they made to the German uranium project during the Second World War. I then use this as a basis for judging Hahn’s postwar apologia as the last president of the Kaiser Wilhelm Society and first president of its successor, the Max Planck Society.

Singly charged energetic helium emitted in solar flares

NASA Technical Reports Server (NTRS)

Hovestadt, D.; Hoefner, H.; Klecker, B.; Scholer, M.; Gloeckler, G.; Ipavich, F. M.; Fan, C. Y.; Fisk, L. A.; Ogallagher, J. J.

1981-01-01

First direct charge state measurements of 0.41-1.05 MeV per nucleon helium accelerated at the sun reveal surprisingly large abundances of singly ionized helium, with typical He(+)/He(++) ratios between 0.04 and 0.21. This unexpected overabundance of He(+) was observed in each of the three large solar-flare particle events which occurred between 1978 August and 1979 October. The data were obtained with the Max-Planck-Institut/University of Maryland Experiment on board the ISEE-3 spacecraft. The observations suggest either strong coronal temperature inhomogeneities including cool regions of approximately 100,000 K or injection of 'cold' chromospheric/photospheric material into the flare acceleration region.

The X-ray microscopy beamline UE46-PGM2 at BESSY

NASA Astrophysics Data System (ADS)

Follath, R.; Schmidt, J. S.; Weigand, M.; Fauth, K.

2010-06-01

The Max Planck Institute for Metal Physics in Stuttgart and the Helmholtz Center Berlin operate a soft X-ray microscopy beamline at the storage ring BESSY II. A collimated PGM serves as monochromator for a scanning X-ray microscope and a full field X-ray microscope at the helical undulator UE46. The selection between both instruments is accomplished via two switchable focusing mirrors. The scanning microscope (SM) is based on the ALS STXM microscope and fabricated by the ACCEL company. The full field microscope (FFM) is currently in operation at the U41-SGM beamline and will be relocated to its final location this year.

Performance testing of a novel off-plane reflection grating and silicon pore optic spectrograph at PANTER

NASA Astrophysics Data System (ADS)

Marlowe, Hannah; McEntaffer, Randall L.; Allured, Ryan; DeRoo, Casey; Miles, Drew M.; Donovan, Benjamin D.; Tutt, James H.; Burwitz, Vadim; Menz, Benedikt; Hartner, Gisela D.; Smith, Randall K.; Günther, Ramses; Yanson, Alex; Vacanti, Giuseppe; Ackermann, Marcelo

2015-05-01

An X-ray spectrograph consisting of aligned, radially ruled off-plane reflection gratings and silicon pore optics (SPO) was tested at the Max Planck Institute for extraterrestrial Physics PANTER X-ray test facility. The SPO is a test module for the proposed Arcus mission, which will also feature aligned off-plane reflection gratings. This test is the first time two off-plane gratings were actively aligned to each other and with a SPO to produce an overlapped spectrum. We report the performance of the complete spectrograph utilizing the aligned gratings module and plans for future development.

Diagnostic standards for dopaminergic augmentation of restless legs syndrome: report from a World Association of Sleep Medicine-International Restless Legs Syndrome Study Group consensus conference at the Max Planck Institute.

PubMed

García-Borreguero, Diego; Allen, Richard P; Kohnen, Ralf; Högl, Birgit; Trenkwalder, Claudia; Oertel, Wolfgang; Hening, Wayne A; Paulus, Walter; Rye, David; Walters, Arthur; Winkelmann, Juliane; Earley, Christopher J

2007-08-01

Augmentation of symptom severity is the main complication of dopaminergic treatment of restless legs syndrome (RLS). The current article reports on the considerations of augmentation that were made during a European Restless Legs Syndrome Study Group (EURLSSG)-sponsored Consensus Conference in April 2006 at the Max Planck Institute (MPI) in Munich, Germany, the conclusions of which were endorsed by the International RLS Study Group (IRLSSG) and the World Association of Sleep Medicine (WASM). The Consensus Conference sought to develop a better understanding of augmentation and generate a better operational definition for its clinical identification. Current concepts of the pathophysiology, clinical features, and therapy of RLS augmentation were evaluated by subgroups who presented a summary of their findings for general consideration and discussion. Recent data indicating sensitivity and specificity of augmentation features for identification of augmentation were also evaluated. The diagnostic criteria of augmentation developed at the National Institutes of Health (NIH) conference in 2002 were reviewed in light of current data and theoretical understanding of augmentation. The diagnostic value and criteria for each of the accepted features of augmentation were considered by the group. A consensus was then developed for a revised statement of the diagnostic criteria for augmentation. Five major diagnostic features of augmentation were identified: usual time of RLS symptom onset each day, number of body parts with RLS symptoms, latency to symptoms at rest, severity of the symptoms when they occur, and effects of dopaminergic medication on symptoms. The quantitative data available relating the time of RLS onset and the presence of other features indicated optimal augmentation criteria of either a 4-h advance in usual starting time for RLS symptoms or a combination of the occurrence of other features. A paradoxical response to changes in medication dose also indicates augmentation. Clinical significance of augmentation is defined. The Consensus Conference agreed upon new operational criteria for the clinical diagnosis of RLS augmentation: the MPI diagnostic criteria for augmentation. Areas needing further consideration for validating these criteria and for understanding the underlying biology of RLS augmentation are indicated.

Time to Exhaustion at the VO2max Velocity in Swimming: A Review

PubMed Central

Fernandes, Ricardo J.; Vilas-Boas, J. Paulo

2012-01-01

The aim of this study was to present a review on the time to exhaustion at the minimum swimming velocity corresponding to maximal oxygen consumption (TLim-vVO2max). This parameter is critical both for the aerobic power and the lactate tolerance bioenergetical training intensity zones, being fundamental to characterize it, and to point out its main determinants. The few number of studies conducted in this topic observed that swimmers were able to maintain an exercise intensity corresponding to maximal aerobic power during 215 to 260 s (elite swimmers), 230 to 260 s (high level swimmers) and 310 to 325 s (low level swimmers), and no differences between genders were reported. TLim-vVO2max main bioenergetic and functional determinants were swimming economy and VO2 slow component (direct relationship), and vVO2max, velocity at anaerobic threshold and blood lactate production (inverse relationship); when more homogeneous groups of swimmers were analysed, the inverse correlation value between TLim-vVO2max and vVO2max was not so evident. In general, TLim-vVO2max was not related to VO2max. TLim-vVO2max seems also to be influenced by stroking parameters, with a direct relationship to stroke length and stroke index, and an inverse correlation with stroke rate. Assessing TLim-vVO2max, together with the anaerobic threshold and the biomechanical general parameters, will allow a larger spectrum of testing protocols application, helping to build more objective and efficient training programs. PMID:23486651

Electrical stimulation site influences the spatial distribution of motor units recruited in tibialis anterior.

PubMed

Okuma, Yoshino; Bergquist, Austin J; Hong, Mandy; Chan, K Ming; Collins, David F

2013-11-01

To compare the spatial distribution of motor units recruited in tibialis anterior (TA) when electrical stimulation is applied over the TA muscle belly versus the common peroneal nerve trunk. Electromyography (EMG) was recorded from the surface and from fine wires in superficial and deep regions of TA. Separate M-wave recruitment curves were constructed for muscle belly and nerve trunk stimulation. During muscle belly stimulation, significantly more current was required to generate M-waves that were 5% of the maximal M-wave (M max; M5%max), 50% M max (M 50%max) and 95% M max (M 95%max) at the deep versus the superficial recording site. In contrast, during nerve trunk stimulation, there were no differences in the current required to reach M5%max, M 50%max or M 95%max between deep and superficial recording sites. Surface EMG reflected activity in both superficial and deep muscle regions. Stimulation over the muscle belly recruited motor units from superficial to deep with increasing stimulation amplitude. Stimulation over the nerve trunk recruited superficial and deep motor units equally, regardless of stimulation amplitude. These results support the idea that where electrical stimulation is applied markedly affects how contractions are produced and have implications for the interpretation of surface EMG data. Copyright © 2013 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

Family Violence and the Need for Prevention Research in First Nations, Inuit, and Métis Communities1

PubMed Central

Andersson, Neil; Nahwegahbow, Amy

2010-01-01

Existing sources produce widely varying estimates of family violence in First Nations, Inuit, and Métis communities; taken together, they imply a convincing if poorly quantified higher risk of family violence in Aboriginal communities, with the greater burden borne by women. With the accelerating HIV epidemic in some Aboriginal communities, prevention of domestic violence takes on even greater urgency. Five planks in a prevention research platform include: training emerging researchers from all Aboriginal groups to promote culturally specific research; systematic review of unpublished and published knowledge of interventions that reduce domestic violence; intervention theory development specific to each community; attention to the particular ethical issues; and methods development focused on interventions. PMID:20975851

Augmentative Device Helps Max Speak. PACER Center ACTion Information Sheets. PHP-c75

ERIC Educational Resources Information Center

PACER Center, 2014

2014-01-01

This Action Information Sheet follows a family's process of selecting and using augmentative and alternative communication to help their young son, Max, speak. Max is affected by global dyspraxia, which makes learning new motor skills--especially speech--quite difficult. For the first years of his life, Max could not say words. Before he and his…

Generalized Maximum Entropy

NASA Technical Reports Server (NTRS)

Cheeseman, Peter; Stutz, John

2005-01-01

A long standing mystery in using Maximum Entropy (MaxEnt) is how to deal with constraints whose values are uncertain. This situation arises when constraint values are estimated from data, because of finite sample sizes. One approach to this problem, advocated by E.T. Jaynes [1], is to ignore this uncertainty, and treat the empirically observed values as exact. We refer to this as the classic MaxEnt approach. Classic MaxEnt gives point probabilities (subject to the given constraints), rather than probability densities. We develop an alternative approach that assumes that the uncertain constraint values are represented by a probability density {e.g: a Gaussian), and this uncertainty yields a MaxEnt posterior probability density. That is, the classic MaxEnt point probabilities are regarded as a multidimensional function of the given constraint values, and uncertainty on these values is transmitted through the MaxEnt function to give uncertainty over the MaXEnt probabilities. We illustrate this approach by explicitly calculating the generalized MaxEnt density for a simple but common case, then show how this can be extended numerically to the general case. This paper expands the generalized MaxEnt concept introduced in a previous paper [3].

Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells

PubMed Central

Suzuki, Ayumu; Hirasaki, Masataka; Hishida, Tomoaki; Wu, Jun; Okamura, Daiji; Ueda, Atsushi; Nishimoto, Masazumi; Nakachi, Yutaka; Mizuno, Yosuke; Okazaki, Yasushi; Matsui, Yasuhisa; Belmonte, Juan Carlos Izpisua; Okuda, Akihiko

2016-01-01

Meiosis is a unique process that allows the generation of reproductive cells. It remains largely unknown how meiosis is initiated in germ cells and why non-germline cells do not undergo meiosis. We previously demonstrated that knockdown of Max expression, a gene encoding a partner of MYC family proteins, strongly activates expression of germ cell-related genes in ESCs. Here we find that complete ablation of Max expression in ESCs results in profound cytological changes reminiscent of cells undergoing meiotic cell division. Furthermore, our analyses uncovers that Max expression is transiently attenuated in germ cells undergoing meiosis in vivo and its forced reduction induces meiosis-like cytological changes in cultured germline stem cells. Mechanistically, Max depletion alterations are, in part, due to impairment of the function of an atypical PRC1 complex (PRC1.6), in which MAX is one of the components. Our data highlight MAX as a new regulator of meiotic onset. PMID:27025988

December 2014 HeartWeek issue of cardiology in the young: highlights of HeartWeek 2014: diseases of the cardiac valves from the foetus to the adult.

PubMed

Jacobs, Jeffrey P

2014-12-01

This December Issue of Cardiology in the Young represents the 12th annual publication generated from the two meetings that compose "HeartWeek in Florida". "HeartWeek in Florida", the joint collaborative project sponsored by the Cardiac Center at the Children's Hospital of Philadelphia, Pennsylvania, together with Johns Hopkins All Children's Heart Institute of Saint Petersburg, Florida, averages over 1000 attendees every year and is now recognised as one of the major planks of continuing medical and nursing education for those working in the fields of diagnosis and treatment of cardiac disease in the foetus, neonate, infant, child, and adult. "HeartWeek in Florida" combines the International Symposium on Congenital Heart Disease, organised by All Children's Hospital and Johns Hopkins Medicine and entering its 15th year, with the Annual Postgraduate Course in Pediatric Cardiovascular Disease, organised by The Children's Hospital of Philadelphia and entering its 18th year. This December, 2014 Issue of Cardiology in the Young features highlights of Johns Hopkins All Children's Heart Institute's 14th Annual International Symposium on Congenital Heart Disease, which was held at the Renaissance Vinoy Resort & Golf Club, Saint Petersburg, Florida, from 15-18 February, 2014. This Symposium was co-sponsored by The American Association for Thoracic Surgery (AATS) and had as its special focus " Diseases of the Cardiac Valves from the Fetus to the Adult ". We acknowledge the tremendous contributions made to paediatric and congenital cardiac care by Duke Cameron and Joel Brenner, and therefore we dedicate this December, 2014 HeartWeek Issue of Cardiology in the Young to them. Duke Cameron is Professor of Surgery at Johns Hopkins University and Cardiac Surgeon-in-Charge at The Johns Hopkins Hospital. Joel Brenner is Professor of Pediatrics at Johns Hopkins University and Director of the Taussig Heart Center at Bloomberg Children's Center, The Johns Hopkins Hospital. Together, Joel and Duke lead the proud paediatric and congenital cardiac programme at The Johns Hopkins Hospital.

MaxSynBio - Avenues towards creating cells from the bottom up.

PubMed

Schwille, Petra; Spatz, Joachim; Landfester, Katharina; Bodenschatz, Eberhard; Herminghaus, Stephan; Sourjik, Victor; Erb, Tobias; Bastiaens, Philippe; Lipowsky, Reinhard; Hyman, Anthony; Dabrock, Peter; Baret, Jean-Christophe; Vidakovic-Koch, Tanja; Bieling, Peter; Dimova, Rumiana; Mutschler, Hannes; Robinson, Tom; Tang, Dora; Wegner, Seraphine; Sundmacher, Kai

2018-05-11

A large Max Planck-based German research consortium ('MaxSynBio') was formed to investigate living systems from a fundamental perspective. The research program of MaxSynBio relies solely on the bottom-up approach to Synthetic Biology. MaxSynBio focuses on the detailed analysis and understanding of essential processes of life, via their modular reconstitution in minimal synthetic systems. The ultimate goal is to construct a basic living unit entirely from non-living components. The fundamental insights gained from the activities in MaxSynBio can eventually be utilized for establishing a new generation of biotechnological processes, which would be based on synthetic cell constructs that replace natural cells currently used in conventional biotechnology. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Overspeed HIIT in Lower-Body Positive Pressure Treadmill Improves Running Performance.

PubMed

Gojanovic, Boris; Shultz, Rebecca; Feihl, Francois; Matheson, Gordon

2015-12-01

Optimal high-intensity interval training (HIIT) regimens for running performance are unknown, although most protocols result in some benefit to key performance factors (running economy (RE), anaerobic threshold (AT), or maximal oxygen uptake (VO2max)). Lower-body positive pressure (LBPP) treadmills offer the unique possibility to partially unload runners and reach supramaximal speeds. We studied the use of LBPP to test an overspeed HIIT protocol in trained runners. Eleven trained runners (35 ± 8 yr, VO2max, 55.7 ± 6.4 mL·kg⁻¹·min⁻¹) were randomized to an LBPP (n = 6) or a regular treadmill (CON, n = 5), eight sessions over 4 wk of HIIT program. Four to five intervals were run at 100% of velocity at VO2max (vVO2max) during 60% of time to exhaustion at vVO2max (Tlim) with a 1:1 work:recovery ratio. Performance outcomes were 2-mile track time trial, VO2max, vVO2max, vAT, Tlim, and RE. LBPP sessions were carried out at 90% body weight. Group-time effects were present for vVO2max (CON, 17.5 vs. 18.3, P = 0.03; LBPP, 19.7 vs. 22.3 km·h⁻¹; P < 0.001) and Tlim (CON, 307.0 vs. 404.4 s, P = 0.28; LBPP, 444.5 vs. 855.5, P < 0.001). Simple main effects for time were present for field performance (CON, -18; LBPP, -25 s; P = 0.002), VO2max (CON, 57.6 vs. 59.6; LBPP, 54.1 vs. 55.1 mL·kg⁻¹·min⁻¹; P = 0.04) and submaximal HR (157.7 vs. 154.3 and 151.4 vs. 148.5 bpm; P = 0.002). RE was unchanged. A 4-wk HIIT protocol at 100% vVO2max improves field performance, vVO2max, VO2max and submaximal HR in trained runners. Improvements are similar if intervals are run on a regular treadmill or at higher speeds on a LPBB treadmill with 10% body weight reduction. LBPP could provide an alternative for taxing HIIT sessions.

MaxAlign: maximizing usable data in an alignment.

PubMed

Gouveia-Oliveira, Rodrigo; Sackett, Peter W; Pedersen, Anders G

2007-08-28

The presence of gaps in an alignment of nucleotide or protein sequences is often an inconvenience for bioinformatical studies. In phylogenetic and other analyses, for instance, gapped columns are often discarded entirely from the alignment. MaxAlign is a program that optimizes the alignment prior to such analyses. Specifically, it maximizes the number of nucleotide (or amino acid) symbols that are present in gap-free columns - the alignment area - by selecting the optimal subset of sequences to exclude from the alignment. MaxAlign can be used prior to phylogenetic and bioinformatical analyses as well as in other situations where this form of alignment improvement is useful. In this work we test MaxAlign's performance in these tasks and compare the accuracy of phylogenetic estimates including and excluding gapped columns from the analysis, with and without processing with MaxAlign. In this paper we also introduce a new simple measure of tree similarity, Normalized Symmetric Similarity (NSS) that we consider useful for comparing tree topologies. We demonstrate how MaxAlign is helpful in detecting misaligned or defective sequences without requiring manual inspection. We also show that it is not advisable to exclude gapped columns from phylogenetic analyses unless MaxAlign is used first. Finally, we find that the sequences removed by MaxAlign from an alignment tend to be those that would otherwise be associated with low phylogenetic accuracy, and that the presence of gaps in any given sequence does not seem to disturb the phylogenetic estimates of other sequences. The MaxAlign web-server is freely available online at http://www.cbs.dtu.dk/services/MaxAlign where supplementary information can also be found. The program is also freely available as a Perl stand-alone package.

Predictive value of pretreatment positron emission tomography/computed tomography in patients with newly diagnosed extranodal natural killer/T-cell lymphoma.

PubMed

Bai, Bing; Huang, Hui-Qiang; Cai, Qi-Chun; Fan, Wei; Wang, Xiao-Xiao; Zhang, Xu; Lin, Ze-Xiao; Gao, Yan; Xia, Yun-Fei; Guo, Ying; Cai, Qing-Qing; Jiang, Wen-Qi; Lin, Tong-Yu

2013-03-01

The role of (18)Fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) in extranodal natural killer/T-cell lymphoma (ENKL) is not well established. This study aimed to investigate the prognostic role of the pretreatment maximum standardized uptake value (SUV(max)) on PET/CT in patients with newly diagnosed ENKL. Among 364 consecutive patients with newly diagnosed ENKL, 81 patients were included and reviewed. The impact of SUV(max) on survival and the relationship between SUV(max) and other clinicopathological parameters were analyzed. The median SUV(max) was 14.6 (range 2.0-45.4). The optimal cutoff value of SUV(max) to predict overall survival (OS) was 15. Patients with high SUV(max) (SUVmax >15) were associated with bulky disease (P < 0.001), local invasion (P = 0.030), high score of Korean Prognostic Index (KPI, P = 0.046), resistance to primary treatment (P = 0.014), poor OS (P < 0.001), and unfavorable progression-free survival (P < 0.001). With a median follow-up of 25.0 months, the median OS was 63.0 months (range 2.0-99.0 months). Multivariate analyses revealed the following independent prognostic factors for OS: age >60 years (P = 0.001), stage III-IV (P = 0.023), SUV(max) >15 (P = 0.020), and bulky disease (>5 cm) (P = 0.002). By using the SUV(max), patients in most subgroups stratified by the KPI or the International Prognostic Index (IPI) were further discriminated in OS with significant statistical difference. Our results suggest the pretreatment SUV(max) is predictive of prognosis in patients with newly diagnosed ENKL. The SUV(max) may provide additional prognostic information for IPI and KPI.

A Role for MORE AXILLARY GROWTH1 (MAX1) in Evolutionary Diversity in Strigolactone Signaling Upstream of MAX21[C][W][OA

PubMed Central

Challis, Richard J.; Hepworth, Jo; Mouchel, Céline; Waites, Richard; Leyser, Ottoline

2013-01-01

Strigolactones (SLs) are carotenoid-derived phytohormones with diverse roles. They are secreted from roots as attractants for arbuscular mycorrhizal fungi and have a wide range of endogenous functions, such as regulation of root and shoot system architecture. To date, six genes associated with SL synthesis and signaling have been molecularly identified using the shoot-branching mutants more axillary growth (max) of Arabidopsis (Arabidopsis thaliana) and dwarf (d) of rice (Oryza sativa). Here, we present a phylogenetic analysis of the MAX/D genes to clarify the relationships of each gene with its wider family and to allow the correlation of events in the evolution of the genes with the evolution of SL function. Our analysis suggests that the notion of a distinct SL pathway is inappropriate. Instead, there may be a diversity of SL-like compounds, the response to which requires a D14/D14-like protein. This ancestral system could have been refined toward distinct ligand-specific pathways channeled through MAX2, the most downstream known component of SL signaling. MAX2 is tightly conserved among land plants and is more diverged from its nearest sister clade than any other SL-related gene, suggesting a pivotal role in the evolution of SL signaling. By contrast, the evidence suggests much greater flexibility upstream of MAX2. The MAX1 gene is a particularly strong candidate for contributing to diversification of inputs upstream of MAX2. Our functional analysis of the MAX1 family demonstrates the early origin of its catalytic function and both redundancy and functional diversification associated with its duplication in angiosperm lineages. PMID:23424248

Mobile MAX-DOAS observation of NO2 and comparison with OMI satellite data in the western coastal areas of the Korean peninsula.

PubMed

Chong, Jihyo; Kim, Young J; Gu, Myojeong; Wagner, Thomas; Song, Chul H

2016-01-01

Ground-based MAX-DOAS measurements have been used to retrieve column densities of atmospheric absorbers such as NO2, SO2, HCHO, and O3. In this study, mobile MAX-DOAS measurements were conducted to map the 2-D distributions of atmospheric NO2 in the western coastal areas of the Korean peninsula. A Mini-MAX-DOAS instrument was mounted on the rooftop of a mobile lab vehicle with a telescope mounted parallel to the driving direction, pointing forward. The measurements were conducted from 21 to 24 December 2010 along the western coastal areas from Gomso harbor (35.59N, 126.61E) to Gunsan harbor (35.98N, 126.67E). During mobile MAX-DOAS observations, high elevation angles were used to avoid shades from nearby obstacles. For the determination of the tropospheric vertical column density (VCD), the air mass factor (AMF) was retrieved by the so-called geometric approximation. The NO2 VCDs from 20 and 45 degree elevation angles were retrieved from mobile MAX-DOAS measurements. The tropospheric NO2 VCDs derived from mobile MAX-DOAS measurements were compared directly to those retrieved by the OMI satellite observations. Mobile MAX-DOAS VCD was in good agreement with OMI tropospheric VCD on most days. However, OMI tropospheric VCD was much higher than that of mobile MAX-DOAS on 23 December 2010. One probable reason for this difference is that OMI retrieval might overestimate NO2 VCD under haze conditions, when a pollution plume was transported over the measurement site. The mobile MAX-DOAS observations reveal much finer spatial patterns of NO2 distributions, which can provide useful information for the validation of satellite observation of atmospheric trace gases. Copyright © 2015 Elsevier Ltd. All rights reserved.

Effects of changing climate on reference crop evapotranspiration over 1961-2013 in Xinjiang, China

NASA Astrophysics Data System (ADS)

Yao, Ning; Li, Yi; Sun, Changfeng

2018-01-01

To know the importance of different climate variables on reference crop evapotranspiration ( ET o), a step-by-step sensitivity analysis of ET o to single, two, and multi-climate variables ( C) was conducted. ET o in north, south, and entire Xinjiang Province, China, over 1961-2013 was estimated using the Penman-Monteith equation. Trends in the involved six Cs (i.e., minimum temperature— T min, average temperature— T ave, maximum temperature— T max, wind speed at 2 m— U 2, sunshine hour— n, and relative humidity— RH) were detected by the modified Mann-Kendall test. Nineteen scenarios of changed Cs were preset to obtain recalculated ET o values considering the actual trend in each C and the Pearson's correlation relationship between ET o and Cs. The results showed that ET o was mostly sensitive to T max, U 2, and n. Sensitivity of ET o to the two overlapped changes of T min and T max caused larger increases in ET o than T max and T ave, T ave and T max, T max and (- n), T max and RH, T max and (- U 2), and T min and T ave, but the overlapped changes (- U 2) and (- n) caused larger decreases in ET o than the other two C scenarios. The simultaneously increased T max, T min, T ave, and RH plus decreased U 2 and n had caused the actual decreases in ET o in Xinjiang. In general, the effects of decreased U 2 and n on decreasing ET o compensated the effects of increased T max on decreasing ET o in Xinjiang.

High-intensity Interval Training in Different Exercise Modes: Lessons from Time to Exhaustion.

PubMed

Sousa, Ana Catarina; Fernandes, Ricardo J; Boas, Joao Paulo Vilas; Figueiredo, Pedro

2018-06-20

To provide information for high-intensity interval training (HIIT) load, we compared the temporal variables of VO 2 response at, and after, a time sustained at the exercise intensity corresponding to VO 2max (Tlim) in different exercise modes. Forty-five trained male swimmers (11), rowers (13), runners (10) and cyclists (11) completed an incremental protocol to determine the velocity (vVO 2max ) or power (wVO 2max ) at VO 2max and a square wave exercise from rest to 100% of vVO 2max /wVO 2max . The temporal variables of VO 2 response were examined using a breath-by-breath gas analyzer. VO 2 responses were not different between exercise modes, except for the percentage of VO 2max at 50% of Tlim, which was ~6% higher in rowing compared to cycling (97.70±2.90 vs 92.40±5.69%, p =0.013). During the recovery period, both swimmers and rowers evidenced higher percentages of VO 2max compared to cyclists at 30 s (65.1±10.4 and 65.7±5.6 vs 52.7±5.6%) and 60 s (41.7±10.8 and 38.4±5.4 vs 30.4±1.8%) time periods, all for p< 0.01. Furthermore, swimmers presented higher time values to reach 50% VO 2max compared to runners and cyclists (51.1±15.6 vs 38.1±6.7 and 33.8±4.7%; p <0.001). When training at 100% of VO 2max intensity, fixed intervals for HIIT could be set freely. However, recovery periods based on time or intensity are exercise-mode dependent. © Georg Thieme Verlag KG Stuttgart · New York.

Prediction of Maximal Oxygen Uptake by Six-Minute Walk Test and Body Mass Index in Healthy Boys.

PubMed

Jalili, Majid; Nazem, Farzad; Sazvar, Akbar; Ranjbar, Kamal

2018-05-14

To develop an equation to predict maximal oxygen uptake (VO2max) based on the 6-minute walk test (6MWT) and body composition in healthy boys. Direct VO2max, 6-minute walk distance, and anthropometric characteristics were measured in 349 healthy boys (12.49 ± 2.72 years). Multiple regression analysis was used to generate VO2max prediction equations. Cross-validation of the VO2max prediction equations was assessed with predicted residual sum of squares statistics. Pearson correlation was used to assess the correlation between measured and predicted VO2max. Objectively measured VO2max had a significant correlation with demographic and 6MWT characteristics (R = 0.11-0.723, P < .01). Multiple regression analysis revealed the following VO2max prediction equation: VO2max (mL/kg/min) = 12.701 + (0.06 × 6-minute walk distance m ) - (0.732 × body mass index kg/m2 ) (R 2 = 0.79, standard error of the estimate [SEE] = 2.91 mL/kg/min, %SEE = 6.9%). There was strong correlation between measured and predicted VO2max (r = 0.875, P < .001). Cross-validation revealed minimal shrinkage (R 2 p = 0.78 and predicted residual sum of squares SEE = 2.99 mL/kg/min). This study provides a relatively accurate and convenient VO2max prediction equation based on the 6MWT and body mass index in healthy boys. This model can be used for evaluation of cardiorespiratory fitness of boys in different settings. Copyright © 2018 Elsevier Inc. All rights reserved.

Objective Measurement of Arterial Flow Before and After Transcatheter Arterial Chemoembolization: A Feasibility Study Using Quantitative Color-Coding Analysis.

PubMed

Lin, Yi-Yang; Lee, Rheun-Chuan; Tseng, Hsiuo-Shan; Liu, Chien-An; Guo, Wan-Yuo; Chang, Cheng-Yen

2015-12-01

To quantitatively measure the hemodynamic change of hepatic artery before and after transcatheter arterial chemoembolization (TACE) of hepatocellular carcinoma (HCC) by quantitative color-coding analysis (QCA). This prospective study registered 64 consecutive HCC patients who underwent segmental or subsegmental TACE with epirubicin and lipiodol at level 2 or 3 of the subjective angiographic chemoembolization endpoint. QCA was used to determine the maximal density time (T(max)) of selected intravascular region of interest (ROI). Relative T(max) (rT(max)) was defined as the T(max) at the selected ROI minus the time of contrast medium spurting from the catheter tip. The rT(max) of hepatic arteries was analyzed before and after embolization. The pre- and post-treatment rT(max) of the landmarks at the treated segmental artery were 1.96 ± 0.48 and 3.14 ± 1.77 s, p < 0.001. According to the treated lobe, 30 patients were treated for the right lobe alone, and 8 patients were treated for the left lobe alone. The pre- and post-rT(max) of treated segmental artery were 2.06 ± 0.54, 3.34 ± 1.63 s, p < 0.001 and 1.89 ± 0.45, 2.68 ± 1.46 s, p = 0.12, respectively. The rT(max) of the proximal lobar hepatic arteries or proper hepatic artery had no significant change before and after TACE. The QCA is feasible to quantify embolization endpoints by comparing the rT(max) in selected hepatic arteries before and after TACE. The rT(max) of treated segmental artery was significant prolonged after optimized procedures.

Evidence of cardiac functional reserve upon exhaustion during incremental exercise to determine VO2max.

PubMed

Elliott, Adrian D; Skowno, Justin; Prabhu, Mahesh; Noakes, Timothy David; Ansley, Les

2015-01-01

There remains considerable debate regarding the limiting factor(s) for maximal oxygen uptake (VO2max). Previous studies have shown that the central circulation may be the primary limiting factor for VO2max and that cardiac work increases beyond VO2max. We sought to evaluate whether the work of the heart limits VO2max during upright incremental cycle exercise to exhaustion. Eight trained men completed two incremental exercise trials, each terminating with exercise at two different rates of work eliciting VO2max (MAX and SUPRAMAX). During each exercise trial we continuously recorded cardiac output using pulse-contour analysis calibrated with a lithium dilution method. Intra-arterial pressure was recorded from the radial artery while pulmonary gas exchange was measured continuously for an assessment of oxygen uptake. The workload during SUPRAMAX (mean±SD: 346.5±43.2 W) was 10% greater than that achieved during MAX (315±39.3 W). There was no significant difference between MAX and SUPRAMAX for Q (28.7 vs 29.4 L/min) or VO2 (4.3 vs 4.3 L/min). Mean arterial pressure was significantly higher during SUPRAMAX, corresponding to a higher cardiac power output (8.1 vs 8.5 W; p<0.06). Despite similar VO2 and Q, the greater cardiac work during SUPRAMAX supports the view that the heart is working submaximally at exhaustion during an incremental exercise test (MAX). Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Chandra Captures Venus In A Whole New Light

NASA Astrophysics Data System (ADS)

2001-11-01

Scientists have captured the first X-ray view of Venus using NASA's Chandra X-ray Observatory. The observations provide new information about the atmosphere of Venus and open a new window for examining Earth's sister planet. Venus in X-rays looks similar to Venus in visible light, but there are important differences. The optically visible Venus is due to the reflection of sunlight and, for the relative positions of Venus, Earth and Sun during these observations, shows a uniform half-crescent that is brightest toward the middle. The X-ray Venus is slightly less than a half-crescent and brighter on the limbs. The differences are due to the processes by which Venus shines in visible and X-ray light. The X-rays from Venus are produced by fluorescence, rather than reflection. Solar X-rays bombard the atmosphere of Venus, knock electrons out of the inner parts of the atoms, and excite the atoms to a higher energy level. The atoms almost immediately return to their lower energy state with the emission of a fluorescent X-ray. A similar process involving ultraviolet light produces the visible light from fluorescent lamps. For Venus, most of the fluorescent X-rays come from oxygen and carbon atoms between 120 and 140 kilometers (74 to 87 miles) above the planet's surface. In contrast, the optical light is reflected from clouds at a height of 50 to 70 kilometers (31 to 43 miles). As a result, Venus' Sun-lit hemisphere appears surrounded by an almost-transparent luminous shell in X-rays. Venus looks brightest at the limb since more luminous material is there. Venus X-ray/Optical Composite of Venus Credit: Xray: NASA/CXC/MPE/K.Dennerl et al., Optical: Konrad Dennerl "This opens up the exciting possibility of using X-ray observations to study regions of the atmosphere of Venus that are difficult to investigate by other means," said Konrad Dennerl of the Max Planck Institute for Extraterrestrial Physics in Garching, Germany, leader of an international team of scientists that conducted the research. The Chandra observation of Venus was also a technological tour de force. The angular separation of Venus from the Sun, as seen from Earth, never exceeds 48 degrees. This relative proximity has prevented star trackers and cameras on other X-ray astronomy satellites from locking onto guide stars and pointing steadily in the direction of Venus to perform such an observation. Venus was observed on Jan. 10, 2001, with the Advanced CCD Imaging Spectrometer (ACIS) detector plus the Low Energy Transmission Grating and on Jan. 13, 2001, with the ACIS alone. Other members of the team were Vadim Burwitz and Jakob Engelhauser, Max Planck Institute; Carey Lisse, University of Maryland, College Park; and Scott Wolk, Harvard-Smithsonian Center for Astrophysics, Cambridge, Mass. These results were presented at this week's "New Visions of X-ray universe in the XMM-Newton and Chandra Era" symposium in Noordwijk, Netherlands. The Low Energy Transmission Grating was built by the Space Research Organization of the Netherlands and the Max Planck Institute, and the ACIS instrument was developed for NASA by The Pennsylvania State University, University Park, and the Massachusetts Institute of Technology (MIT), Cambridge. NASA's Marshall Space Flight Center in Huntsville, Ala., manages the Chandra program. The Smithsonian's Chandra X-ray Center controls science and flight operations from Cambridge, Mass.

Modification of the Fox method to predict maximum oxygen uptake in female university students of Kolkata, India.

PubMed

Bandyopadhyay, Amit

2011-12-01

The present study was aimed to develop a simple method, i.e. the modified Fox test protocol (MFT) to predict VO2(max) in female sedentary university students of Kolkata, India. One hundred and eleven (111) healthy untrained female students of the University of Calcutta (mean age, body height and body mass of 22.76 ± 1.72 years, 163.52 ± 4.70 cm and 53.03 ± 3.78 kg, respectively) were randomly sampled for the study. They were further randomly divided into the study group (n = 60) and confirmatory group (n = 51). Direct estimation of the maximum oxygen uptake (VO2(max)) comprised an incremental bicycle exercise followed by expired gas analysis by the Scholander micro-gas analyzer. The submaximal heart rate (HR(sub)) was measured at the completion of five min of exercise at 110W workload. HR(sub) exhibited significant negative correlation (r = -0.87, P < 0.001) with VO2(max). Application of the computed norm in the confirmatory group depicted insignificant difference between VO2(max) and predicted VO2(max) or PVO2(max). Limits of agreement between PVO2(max) and VO2(max) were substantially small. The standard error of estimate of the norm was also substantially small. From the present study, MFT is recommended for application in the sedentary female university students for accurate and reliable assessment of cardiorespiratory fitness in terms of VO2(max).

Years in Cologne.

PubMed

Rajewsky, Klaus

2013-01-01

This review describes the building and scientific activity of the Immunology Department at the Institute for Genetics in Cologne, cofounded by Max Delbrück in post-World War II Germany. The protagonist, a child of Russian emigrants, became interested in antibodies as a postdoc at the Pasteur Institute in Paris and a proponent of the antigen-bridge model of T-B cell collaboration during his early time in Cologne. He was challenged by the gap between cellular immunology and molecular genetics and profited from the advances of the latter as well as postwar economic growth in Germany. The Immunology Department became a place, and little universe in itself, where young scientists from all over the world came together to study cellular and molecular mechanisms of antibody formation. This included work on normal and malignant B cells in the human, particularly the origin of Hodgkin lymphoma, but the main focus was on B cell development and homeostasis, the germinal center reaction, and immunological memory, developing recombinase-assisted and conditional gene targeting in mice as a main technical tool.

Magnetic assessment and modelling of the Aramis undulator beamline

PubMed Central

Calvi, M.; Camenzuli, C.; Ganter, R.; Sammut, N.; Schmidt, Th.

2018-01-01

Within the SwissFEL project at the Paul Scherrer Institute (PSI), the hard X-ray line (Aramis) has been equipped with short-period in-vacuum undulators, known as the U15 series. The undulator design has been developed within the institute itself, while the prototyping and the series production have been implemented through a close collaboration with a Swiss industrial partner, Max Daetwyler AG, and several subcontractors. The magnetic measurement system has been built at PSI, together with all the data analysis tools. The Hall probe has been designed for PSI by the Swiss company SENIS. In this paper the general concepts of both the mechanical and the magnetic properties of the U15 series of undulators are presented. A description of the magnetic measurement equipment is given and the results of the magnetic measurement campaign are reported. Lastly, the data reduction methods and the associated models are presented and their actual implementation in the control system is detailed. PMID:29714179

On the history of the quantum. Introduction to the HQ4 special issue

NASA Astrophysics Data System (ADS)

Navarro, Jaume; Blum, Alexander; Lehner, Christoph

2017-11-01

Eight years ago, a special issue in this journal published a dozen papers with new studies on the history of quantum physics. That issue was an output of a conference in Utrecht one year earlier, the second in a series organized by the then existing large-scale project coordinated by the Max Planck Institute for the History of Science and the Fritz Haber Institute. Since then, that project has produced a number of publications, workshops and other academic outcomes, but more importantly, it triggered the consolidation of an international community of historians and philosophers of science producing novel work on the history of quantum physics. Five years after the third meeting, which took place in Berlin in 2010, many of the scholars from that group and some new ones met for four days in Donostia/San Sebastian for the HQ4 meeting. The time was ripe for new results to be shared and discussed, and this issue collects some of the papers presented at that gathering.

Phoenix Robotic Arm

NASA Technical Reports Server (NTRS)

2007-01-01

A vital instrument on NASA's Phoenix Mars Lander is the robotic arm, which will dig into the icy soil and bring samples back to the science deck of the spacecraft for analysis. In September 2006 at a Lockheed Martin Space Systems clean room facility near Denver, spacecraft technician Billy Jones inspects the arm during the assembly phase of the mission.

Using the robotic arm -- built by the Jet Propulsion Laboratory, Pasadena -- the Phoenix mission will study the history of water and search for complex organic molecules in the ice-rich soil.

The Phoenix mission is led by Principal Investigator Peter H. Smith of the University of Arizona, Tucson, with project management at NASA's Jet Propulsion Laboratory and development partnership with Lockheed Martin Space Systems. International contributions for Phoenix are provided by the Canadian Space Agency, the University of Neuchatel (Switzerland), the University of Copenhagen, and the Max Planck Institute in Germany. JPL is a division of the California Institute of Technology in Pasadena.

High angular resolution mm- and submm-observations of dense molecular gas in M82

NASA Technical Reports Server (NTRS)

Wild, W.; Eckart, Andreas; Genzel, Reinhard; Harris, Andrew I.; Jackson, James M.; Jaffe, D. T.; Lugten, J. B.; Stutzki, J.

1990-01-01

Researchers observed CO(7-6), CO(3-2), HCN(3-2) and HCO+(3-2) line emission toward the starburst nucleus of M82 and have obtained an upper limit to H13CN(3-2). These are the first observations of the CO(7-6), HCN(3-2) and HCO+(3-2) lines in any extragalactic source. Researchers took the CO(7-6) spectrum in January 1988 at the Infrared Telescope Facility (IRTF) with the Max Planck Institute for Extraterrestrial Physics/Univ. of California, Berkeley 800 GHz Heterodyne Receiver. In March 1989 researchers used the Institute for Radio Astronomy in the Millimeter range (IRAM) 30 m telescope to observe the CO(3-2) line with the new MPE 350 GHz Superconductor Insulator Superconductor (SIS) receiver and the HCN(3-2) and HCO+(3-2) lines with the (IRAM) 230 GHz SIS receiver (beam 12" FWHM, Blundell et al. 1988). The observational parameters are summarized.

Environmental Testing in Thermal Vacuum Chamber

NASA Technical Reports Server (NTRS)

2007-01-01

Inside a thermal vacuum at Lockheed Martin Space Systems, Denver, technicians prepare NASA's Phoenix Mars Lander for environmental testing.

The Phoenix lander was encapsulated in its aeroshell -- which included both the back shell and heat shield -- as it was subjected to extreme cold and heat in a vacuum, space-like condition. The spacecraft undergoes extensive environmental testing to confirm Phoenix will perform in the extreme conditions it will experience during its trip from Earth to Mars, during its arrival and landing, and while it works on the surface of Mars.

The Phoenix mission is led by Principal Investigator Peter H. Smith of the University of Arizona, Tucson, with project management at NASA's Jet Propulsion Laboratory and development partnership with Lockheed Martin Space Systems. International contributions for Phoenix are provided by the Canadian Space Agency, the University of Neuchatel (Switzerland), the University of Copenhagen, and the Max Planck Institute in Germany. JPL is a division of the California Institute of Technology in Pasadena.

The next large helical devices

NASA Astrophysics Data System (ADS)

Iiyoshi, Atsuo; Yamazaki, Kozo

1995-06-01

Helical systems have the strong advantage of inherent steady-state operation for fusion reactors. Two large helical devices with fully superconducting coil systems are presently under design and construction. One is the LHD (Large Helical Device) [Fusion Technol. 17, 169 (1990)] with major radius=3.9 m and magnetic field=3-4 T, that is under construction during 1990-1997 at NIFS (National Institute for Fusion Science), Nagoya/Toki, Japan; it features continuous helical coils and a clean helical divertor focusing on edge configuration optimization. The other one in the W7-X (Wendelstein 7-X) [in Plasma Physics and Controlled Fusion Nuclear Research, 1990, (International Atomic Energy Agency, Vienna, 1991), Vol. 3, p. 525] with major radius=5.5 m and magnetic field=3 T, that is under review at IPP (Max-Planck Institute for Plasma Physics), Garching, Germany; it has adopted a modular coil system after elaborate optimization studies. These two programs are complementary in promoting world helical fusion research and in extending the understanding of toroidal plasmas through comparisons with large tokamaks.

Microscopy of semiconducting materials

NASA Astrophysics Data System (ADS)

Pennycook, S. J.

1991-04-01

The purpose of the trip was to present an invited talk at the 7th Oxford Conference on Microscopy of Semiconducting Materials entitled, High-Resolution Z-Contrast Imaging of Heterostructures and Superlattices, (Oxford, United Kingdom) and to visit VG Microscopes, East Grinstead, for discussions on the progress of the Oak Ridge National Laboratory (ORNL) 300-kV high-resolution scanning transmission electron microscope (STEM), which is currently on order. The traveler also visited three other institutions with 100-kV STEMs that either have or intend to purchase the necessary modifications to provide Z-contrast capability similar to that of the existing ORNL machine. Specifically, Max-Planck Institut fuer Metallforschung (Stuttgart, Germany); Cambridge University, Department of Materials Science and Metallurgy (Cambridge, United Kingdom); and Cavendish Laboratory, Cambridge University (Cambridge, United Kingdom) were visited. In addition, discussions were held with C. Humphreys on the possibility of obtaining joint funding for collaborative research involving electron beam writing and Z-contrast imaging in the Cambridge and Oak Ridge STEMs, respectively.

Work on Phoenix Science Deck

NASA Technical Reports Server (NTRS)

2007-01-01

Lockheed Martin Space Systems technicians Jim Young (left) and Jack Farmerie (right) work on the science deck of NASA's Phoenix Mars Lander.

The spacecraft was built in a 100,000-class clean room near Denver under NASA's planetary protection practices to keep organics from being taken to Mars. The lander's robotic arm, built by the Jet Propulsion Laboratory, Pasadena, is seen at the top of the picture. The color and grey dots will be used to calibrate the spacecraft's Surface Stereoscopic Imager camera once the spacecraft has landed on the red planet.

The Phoenix mission is led by Principal Investigator Peter H. Smith of the University of Arizona, Tucson, with project management at NASA's Jet Propulsion Laboratory and development partnership with Lockheed Martin Space Systems. International contributions for Phoenix are provided by the Canadian Space Agency, the University of Neuchatel (Switzerland), the University of Copenhagen, and the Max Planck Institute in Germany. JPL is a division of the California Institute of Technology in Pasadena.

Inverse relationship between VO2max and economy/efficiency in world-class cyclists.

PubMed

Lucía, Alejandro; Hoyos, Jesus; Pérez, Margarita; Santalla, Alfredo; Chicharro, José L

2002-12-01

To determine the relationship that exists between VO2max and cycling economy/efficiency during intense, submaximal exercise in world-class road professional cyclists. METHODS Each of 11 male cyclists (26+/-1 yr (mean +/- SEM); VO2max: 72.0 +/- 1.8 mL x kg(-1) x min(-1)) performed: 1) a ramp test for O2max determination and 2) a constant-load test of 20-min duration at the power output eliciting 80% of subjects' VO2max during the previous ramp test (mean power output of 385 +/- 7 W). Cycling economy (CE) and gross mechanical efficiency (GE) were calculated during the constant-load tests. CE and GE averaged 85.2 +/- 2.3 W x L(-1) x min(-1) and 24.5 +/- 0.7%, respectively. An inverse, significant correlation was found between 1) VO2max (mL x kg(-0.32) x min(-1)) and both CE (r = -0.71; P = 0.01) and GE (-0.72; P = 0.01), and 2) VO2max (mL x kg(-1) x min(-1)) and both CE (r = -0.65; P = 0.03) and GE (-0.64; P = 0.03). A high CE/GE seems to compensate for a relatively low VO2max in professional cyclists.

Joint graph cut and relative fuzzy connectedness image segmentation algorithm.

PubMed

Ciesielski, Krzysztof Chris; Miranda, Paulo A V; Falcão, Alexandre X; Udupa, Jayaram K

2013-12-01

We introduce an image segmentation algorithm, called GC(sum)(max), which combines, in novel manner, the strengths of two popular algorithms: Relative Fuzzy Connectedness (RFC) and (standard) Graph Cut (GC). We show, both theoretically and experimentally, that GC(sum)(max) preserves robustness of RFC with respect to the seed choice (thus, avoiding "shrinking problem" of GC), while keeping GC's stronger control over the problem of "leaking though poorly defined boundary segments." The analysis of GC(sum)(max) is greatly facilitated by our recent theoretical results that RFC can be described within the framework of Generalized GC (GGC) segmentation algorithms. In our implementation of GC(sum)(max) we use, as a subroutine, a version of RFC algorithm (based on Image Forest Transform) that runs (provably) in linear time with respect to the image size. This results in GC(sum)(max) running in a time close to linear. Experimental comparison of GC(sum)(max) to GC, an iterative version of RFC (IRFC), and power watershed (PW), based on a variety medical and non-medical images, indicates superior accuracy performance of GC(sum)(max) over these other methods, resulting in a rank ordering of GC(sum)(max)>PW∼IRFC>GC. Copyright © 2013 Elsevier B.V. All rights reserved.

Enhanced cadmium phytoremediation of Glycine max L. through bioaugmentation of cadmium-resistant bacteria assisted by biostimulation.

PubMed

Rojjanateeranaj, Pongsarun; Sangthong, Chirawee; Prapagdee, Benjaphorn

2017-10-01

This study examined the potential of three strains of cadmium-resistant bacteria, including Micrococcus sp., Pseudomonas sp. and Arthrobacter sp., to promote root elongation of Glycine max L. seedlings, soil cadmium solubility and cadmium phytoremediation in G. max L. planted in soil highly polluted with cadmium with and without nutrient biostimulation. Micrococcus sp. promoted root length in G. max L. seedlings under toxic cadmium conditions. Soil inoculation with Arthrobacter sp. increased the bioavailable fraction of soil cadmium, particularly in soil amended with a C:N ratio of 20:1. Pot culture experiments observed that the highest plant growth was in Micrococcus sp.-inoculated plants with nutrient biostimulation. Cadmium accumulation in the roots, stems and leaves of G. max L. was significantly enhanced by Arthrobacter sp. with nutrient biostimulation. A combined use of G. max L. and Arthrobacter sp. with nutrient biostimulation accelerated cadmium phytoremediation. In addition, cadmium was retained in roots more than in stems and leaves and G. max L. had the lowest translocation factor at all growth stages, suggesting that G. max L. is a phytostabilizing plant. We concluded that biostimulation-assisted bioaugmentation is an important strategy for improving cadmium phytoremediation efficiency. Copyright © 2017 Elsevier Ltd. All rights reserved.

Relationship between simulated extravehicular activity tasks and measurements of physical performance.

PubMed

Ade, C J; Broxterman, R M; Craig, J C; Schlup, S J; Wilcox, S L; Barstow, T J

2014-11-01

The purpose was to evaluate the relationships between tests of fitness and two activities that simulate components of Lunar- and Martian-based extravehicular activities (EVA). Seventy-one subjects completed two field tests: a physical abilities test and a 10km Walkback test. The relationships between test times and the following parameters were determined: running V˙O2max, gas exchange threshold (GET), speed at V˙O2max (s-V˙O2max), highest sustainable rate of aerobic metabolism [critical speed (CS)], and the finite distance that could be covered above CS (D'): arm cranking V˙O2peak, GET, critical power (CP), and the finite work that can be performed above CP (W'). CS, running V˙O2max, s-V˙O2max, and arm cranking V˙O2peak had the highest correlations with the physical abilities field test (r=0.66-0.82, P<0.001). For the 10km Walkback, CS, s-V˙O2max, and running V˙O2max were significant predictors (r=0.64-0.85, P<0.001). CS and to a lesser extent V˙O2max are most strongly associated with tasks that simulate aspects of EVA performance, highlighting CS as a method for evaluating astronaut physical capacity. Copyright © 2014 Elsevier B.V. All rights reserved.

Utilities for master source code distribution: MAX and Friends

NASA Technical Reports Server (NTRS)

Felippa, Carlos A.

1988-01-01

MAX is a program for the manipulation of FORTRAN master source code (MSC). This is a technique by which one maintains one and only one master copy of a FORTRAN program under a program developing system, which for MAX is assumed to be VAX/VMS. The master copy is not intended to be directly compiled. Instead it must be pre-processed by MAX to produce compilable instances. These instances may correspond to different code versions (for example, double precision versus single precision), different machines (for example, IBM, CDC, Cray) or different operating systems (i.e., VAX/VMS versus VAX/UNIX). The advantage os using a master source is more pronounced in complex application programs that are developed and maintained over many years and are to be transported and executed on several computer environments. The version lag problem that plagues many such programs is avoided by this approach. MAX is complemented by several auxiliary programs that perform nonessential functions. The ensemble is collectively known as MAX and Friends. All of these programs, including MAX, are executed as foreign VAX/VMS commands and can easily be hidden in customized VMS command procedures.

Hidden Risks of Erectile Dysfunction "Treatments" Sold Online

MedlinePlus

... screen and stop these shipments from entering U.S. commerce," says Huascar Batista, team leader of OOC's Import- ... Free Rhino V Max V.Max True Man Energy Max HS Joy of Love NaturalUp Blue Steel ...

Smoke signals and seed dormancy

PubMed Central

Waters, Mark T; Nelson, David C

2011-01-01

The Arabidopsis thaliana F-box protein MAX2 has been discovered in four separate genetic screens, indicating that it has roles in leaf senescence, seedling photosensitivity, shoot outgrowth and seed germination. Both strigolactones and karrikins can regulate A. thaliana seed germination and seedling photomorphogenesis in a MAX2-dependent manner, but only strigolactones inhibit shoot branching. How MAX2 mediates specific responses to both classes of structurally-related signals, and the origin of its dual role remains unknown. The moss Physcomitrella patens utilizes strigolactones and MAX2 orthologs are present across the land plants, suggesting that this signaling system could have an ancient origin. The seed of parasitic Orobanchaceae species germinate preferentially in response to strigolactones over karrikins, and putative Orobanchaceae MAX2 orthologs form a sub-clade distinct from those of other dicots. These observations suggest that lineage-specific evolution of MAX2 may have given rise to specialized responses to these signaling molecules. PMID:22019642

The Effect of Habitual Smoking on VO2max

NASA Technical Reports Server (NTRS)

Wier, Larry T.; Suminski, Richard R.; Poston, Walker S.; Randles, Anthony M.; Arenare, Brian; Jackson, Andrew S.

2008-01-01

VO2max is associated with many factors, including age, gender, physical activity, and body composition. It is popularly believed that habitual smoking lowers aerobic fitness. PURPOSE: to determine the effect of habitual smoking on VO2max after controlling for age, gender, activity and BMI. METHODS: 2374 men and 375 women employed at the NASA/Johnson Space Center were measured for VO2max by indirect calorimetry (RER>=1.1), activity by the 11 point (0-10) NASA Physical Activity Status Scale (PASS), BMI and smoking pack-yrs (packs day*y of smoking). Age was recorded in years and gender was coded as M=1, W=0. Pack.y was made a categorical variable consisting of four levels as follows: Never Smoked (0), Light (1-10), Regular (11-20), Heavy (>20). Group differences were verified by ANOVA. A General Linear Models (GLM) was used to develop two models to examine the relationship of smoking behavior on VO2max. GLM #1(without smoking) determined the combined effects of age, gender, PASS and BMI on VO2max. GLM #2 (with smoking) determined the added effects of smoking (pack.y groupings) on VO2max after controlling for age, gender, PASS and BMI. Constant errors (CE) were calculated to compare the accuracy of the two models for estimating the VO2max of the smoking subgroups. RESULTS: ANOVA affirmed the mean VO2max of each pack.y grouping decreased significantly (p<0.01) as the level of smoking exposure increased. GLM #1 showed that age, gender, PASS and BMI were independently related with VO2max (R2 = 0.642, SEE = 4.90, p<0.001). The added pack.y variables in GLM #2 were statistically significant (R2 change = 0.7%, p<0.01). Post hoc analysis showed that compared to Never Smoked, the effects on VO2max from Light and Regular smoking habits were -0.83 and -0.85 ml.kg- 1.min-1 respectively (p<0.05). The effect of Heavy smoking on VO2max was -2.56 ml.kg- 1.min-1 (p<0.001). The CE s of each smoking group in GLM #2 was smaller than the CE s of the smoking group counterparts in GLM #1. CONCLUSIONS: After accounting for the effects of gender, age, PASS and BMI the effect of habitual smoking on reducing VO2max is minimal, about 0.85 ml/kg/min, until the habit exceeds 20 pack.y at which point an additional decrease of 1.71 ml/kg/min is noted. Adding pack.y data improves the accuracy of predicting the VO2max of smokers.

Blunted perception of neural respiratory drive and breathlessness in patients with cystic fibrosis

PubMed Central

Jolley, Caroline J.; Elston, Caroline; Moxham, John; Rafferty, Gerrard F.

2016-01-01

The electromyogram recorded from the diaphragm (EMGdi) and parasternal intercostal muscle using surface electrodes (sEMGpara) provides a measure of neural respiratory drive (NRD), the magnitude of which reflects lung disease severity in stable cystic fibrosis. The aim of this study was to explore perception of NRD and breathlessness in both healthy individuals and patients with cystic fibrosis. Given chronic respiratory loading and increased NRD in cystic fibrosis, often in the absence of breathlessness at rest, we hypothesised that patients with cystic fibrosis would be able to tolerate higher levels of NRD for a given level of breathlessness compared to healthy individuals during exercise. 15 cystic fibrosis patients (mean forced expiratory volume in 1 s (FEV1) 53.5% predicted) and 15 age-matched, healthy controls were studied. Spirometry was measured in all subjects and lung volumes measured in the cystic fibrosis patients. EMGdi and sEMGpara were recorded at rest and during incremental cycle exercise to exhaustion and expressed as a percentage of maximum (% max) obtained from maximum respiratory manoeuvres. Borg breathlessness scores were recorded at rest and during each minute of exercise. EMGdi % max and sEMGpara % max and associated Borg breathlessness scores differed significantly between healthy subjects and cystic fibrosis patients at rest and during exercise. The relationship between EMGdi % max and sEMGpara % max and Borg score was shifted to the right in the cystic fibrosis patients, such that at comparable levels of EMGdi % max and sEMGpara % max the cystic fibrosis patients reported significantly lower Borg breathlessness scores compared to the healthy individuals. At Borg score 1 (clinically significant increase in breathlessness from baseline) corresponding levels of EMGdi % max (20.2±12% versus 32.15±15%, p=0.02) and sEMGpara % max (18.9±8% versus 29.2±15%, p=0.04) were lower in the healthy individuals compared to the cystic fibrosis patients. In the cystic fibrosis patients EMGdi % max at Borg score 1 was related to the degree of airways obstruction (FEV1) (r=−0.664, p=0.007) and hyperinflation (residual volume/total lung capacity) (r=0.710, p=0.03). This relationship was not observed for sEMGpara % max. These data suggest that compared to healthy individuals, patients with cystic fibrosis can tolerate much higher levels of NRD before increases in breathlessness from baseline become clinically significant. EMGdi % max and sEMGpara % max provide physiological tools with which to elucidate factors underlying inter-individual differences in breathlessness perception. PMID:27730171

Patterns of Senescence in Human Cardiovascular Fitness: VO2max in Subsistence and Industrialized Populations

PubMed Central

Pisor, Anne C.; Gurven, Michael; Blackwell, Aaron D.; Kaplan, Hillard; Yetish, Gandhi

2014-01-01

Objectives This study explores whether cardiovascular fitness levels and senescent decline are similar in the Tsimane of Bolivia and Canadians, as well as other subsistence and industrialized populations. Among Tsimane, we examine whether morbidity predicts lower levels and faster decline of cardiovascular fitness, or whether their lifestyle (e.g., high physical activity) promotes high levels and slow decline. Alternatively, high activity levels and morbidity might counterbalance such that Tsimane fitness levels and decline are similar to those in industrialized populations. Methods Maximal oxygen uptake (VO2max) was estimated using a step test heart rate method for 701 participants. We compared these estimates to the Canadian Health Measures Survey and previous studies in industrialized and subsistence populations. We evaluated whether health indicators and proxies for market integration were associated with VO2max levels and rate of decline for the Tsimane. Results The Tsimane have significantly higher levels of VO2max and slower rates of decline than Canadians; initial evidence suggests differences in VO2max levels between other subsistence and industrialized populations. Low hemoglobin predicts low VO2max for Tsimane women while helminth infection predicts high VO2max for Tsimane men, though results might be specific to the VO2max scaling parameter used. No variables tested interact with age to moderate decline. Conclusions The Tsimane demonstrate higher levels of cardiovascular fitness than industrialized populations, but levels similar to other subsistence populations. The high VO2max of Tsimane is consistent with their high physical activity and few indicators of cardiovascular disease, measured in previous studies. PMID:24022886

Simplification of the Gardner model: effects on maximum upward flux in the presence of a shallow water table

NASA Astrophysics Data System (ADS)

Xing, Xuguang; Ma, Xiaoyi

2018-06-01

The maximum upward flux ( E max) is a control condition for the development of groundwater evaporation models, which can be predicted through the Gardner model. A high-precision E max prediction helps to improve irrigation practice. When using the Gardner model, it has widely been accepted to ignore parameter b (a soil-water constant) for model simplification. However, this may affect the prediction accuracy; therefore, how parameter b affects E max requires detailed investigation. An indoor one-dimensional soil-column evaporation experiment was conducted to observe E max in the presence of a water table of depth 50 cm. The study consisted of 13 treatments based on four solutes and three concentrations in groundwater: KCl, NaCl, CaCl2, and MgCl2, with concentrations of 5, 30, and 100 g/L (salty groundwater); distilled water was used as a control treatment. Results indicated that for the experimental homogeneous loam, the average E max for the treatments supplied by salty groundwater was larger than that supplied by distilled water. Furthermore, during the prediction of the Gardner-model-based E max, ignoring b and including b always led to an overestimate and underestimate, respectively, compared to the observed E max. However, the maximum upward flux calculated including b (i.e. E bmax) had higher accuracy than that ignoring b for E max prediction. Moreover, the impact of ignoring b on E max gradually weakened with increasing b value. This research helps to reveal the groundwater evaporation mechanism.

Human mitochondrial haplogroup H: the highest VO2max consumer--is it a paradox?

PubMed

Martínez-Redondo, Diana; Marcuello, Ana; Casajús, José A; Ara, Ignacio; Dahmani, Yahya; Montoya, Julio; Ruiz-Pesini, Eduardo; López-Pérez, Manuel J; Díez-Sánchez, Carmen

2010-03-01

Mitochondrial background has been demonstrated to influence maximal oxygen uptake (VO(2max), in mLkg(-1)min(-1)), but this genetic influence can be compensated for by regular exercise. A positive correlation among electron transport chain (ETC) coupling, ATP and reactive oxygen species (ROS) production has been established, and mitochondrial variants have been reported to show differences in their ETC performance. In this study, we examined in detail the VO(2max) differences found among mitochondrial haplogroups. We recruited 81 healthy male Spanish Caucasian individuals and determined their mitochondrial haplogroup. Their VO(2max) was determined using incremental cycling exercise (ICE). VO(2max) was lower in J than in non-J haplogroup individuals (P=0.04). The H haplogroup was responsible for this difference (VO(2max); J vs. H; P=0.008) and this group also had significantly higher mitochondrial oxidative damage (mtOD) than the J haplogroup (P=0.04). In agreement with these results, VO(2max) and mtOD were positively correlated (P=0.01). Given that ROS production is the major contributor to mtOD and consumes four times more oxygen per electron than the ETC, our results strongly suggest that ROS production is responsible for the higher VO(2max) found in the H variant. These findings not only contribute to a better understanding of the mechanisms underneath VO(2max), but also help to explain some reported associations between mitochondrial haplogroups and mtOD with longevity, sperm motility, premature aging and susceptibility to different pathologies.

[Manual lifting and manual transport: risk assessment and prevalence of work-related diseases in construction companies in Basilicata].

PubMed

Nicoletti, S; Battevi, N; Colafemmina, G; Di Leone, G; Satriani, G; Ragone, P; Occhipinti, E

2013-01-01

The Basilicata Regional Headquarters of the Italian Institute for Insurance against Occupational Accidents and Disease (INAIL) and the Basilicata association of small building enterprises (Edilcassa di Basilicata) promoted a research project to assess the risk of manual lifting and manual transport in construction enterprises in the Basilicata Region and estimate the prevalence of related diseases. Manual lifting risk assessment was performed by calculating the VLI of 204 working days in as many building workers. Manual transport risk assessment was carried out comparing the weights transported (on the 204 days tested) with the reference values of the "Snoock and Ciriello" tables. Manual Ifting risk was present on 195 of the 204 days, with an average value of VLI equal to 2.1 (min 0.4, max 8.5), with higher values in the restructuring sector (VLI average of 2.3, min 0.4, max 8.5), and no significant differences between the different tasks. Manual transport risk was present on 129 of the 204 days, with average values of 1.2 (min 0.2, max 3.3), with no significant differences between the different tasks analyzed For both risks additional factors were present that were not analyzed by the methods of assessment used (for manual lifting: 8.8% of the geometries in the critical area; for manual transport: 39% of transport on shoulders, 42.5% on a route with uneven surface and 31.9% on a sloping route), so it is likely that the actual risk is greater than that indicated by the synthetic indices of exposure. The medical questionnaire showed from the case histories that 148 out of 546 subjects were positive for the threshold forpain or discomfort in the lumbosacral spine area and 99 out of 546 subjects reported suffering from an already diagnosed herniated spinal disk. Only 18% of osteoarticular diseases was reported to the Insurance Institute, al though there was widespread awareness that the diseases in question might be related to work. Diseases of the spine were responsible for 1.9% of absenteeism, equal to 30-40% of total absenteeism ofworkers enrolled in "Edilcassa di Basilicata". The method used provides a solid basis for evaluating the two risks in the construction industry, where employment is subject to extreme organizational, environmental and structural (machines, tools, operators involved) variability. Employment in the construction industry involves significant exposure to the two risks, counting for 30-40% of total absenteeism in this sector.

Motor-neuron pool excitability of the lower leg muscles after acute lateral ankle sprain.

PubMed

Klykken, Lindsey W; Pietrosimone, Brian G; Kim, Kyung-Min; Ingersoll, Christopher D; Hertel, Jay

2011-01-01

Neuromuscular deficits in leg muscles that are associated with arthrogenic muscle inhibition have been reported in people with chronic ankle instability, yet whether these neuromuscular alterations are present in individuals with acute sprains is unknown. To compare the effect of acute lateral ankle sprain on the motor-neuron pool excitability (MNPE) of injured leg muscles with that of uninjured contralateral leg muscles and the leg muscles of healthy controls. Case-control study. Laboratory. Ten individuals with acute ankle sprains (6 females, 4 males; age= 19.2 ± 3.8 years, height= 169.4 ± 8.5 cm, mass= 66.3 ± 11.6 kg) and 10 healthy individuals(6 females,4 males; age= 20.6 ± 4.0 years, height = 169.9 ± 10.6 cm, mass= 66.3 ± 10.2 kg) participated. The independent variables were group (acute ankle sprain, healthy) and limb (injured, uninjured). Separate dependent t tests were used to determine differences in MNPE between legs. The MNPE of the soleus, fibularis longus, and tibialis anterior was measured by the maximal Hoffmann reflex (H(max)) and maximal muscle response (M(max)) and was then normalized using the H(max):M(max) ratio. The soleus MNPE in the ankle-sprain group was higher in the injured limb (H(max):M(max) = 0.63; 95% confidence interval [Cl],0.46, 0.80) than the uninjured limb (H(max):M(max) = 0.47; 95%Cl, 0.08, 0.93)(t(6) = 3.62,P =.01).In the acute ankle-sprain group, tibialis anterior MNPE tended to be lower in the injured ankle (H(max):M(max) =0.06; 95% Cl, 0.01, 0.10) than in the uninjured ankle (H(max):M(max) =0.22; 95%Cl, 0.09, 0.35),but this finding was not different (t(9) =-2.01, P =.07). No differences were detected between injured (0.22; 95% Cl, 0.14, 0.29) and uninjured (0.25; 95%Cl, 0.12, 0.38) ankles for the fibularis longus in the ankle-sprain group (t(9) =-0.739, P =.48). We found no side-to-side differences in any muscle among the healthy group. Facilitated MNPE was present in the involved soleus muscle of patients with acute ankle sprains, but no differences were found in the fibularis longus or tibialis anterior muscles.

[Is physical activity an elixir?].

PubMed

Lacza, Gyöngyvér; Radák, Zsolt

2013-05-19

Physical exercise has systemic effects, and it can regulate all the organs. The relative maximal aerobic oxygen uptake (VO2max) could have been important in the evolution of humans, since higher VO2max meant better hunting abilities for the Stone Age man. However, it appears that high level of VO2max is also important today, in the 21st century to prevent cardiovascular diseases, cancer and neurodegenerative diseases. High level of VO2max is not just preventive against a wide spectrum of diseases, but it associated with better function of many organs. Relevant data suggest that high level of VO2max is a key factor in prevention of diseases and survival even at the modern civilized world.

NCEP Air Quality Forecast(AQF). NOAA/NWS/NCEP/EMC

Science.gov Websites

19 20 21 22 23 24 25 26 27 28 29 30 31 Select Cycle: 12Z 06Z Select Field: target(4Z-4Z) day_1 O3 1h max target(4Z-4Z) day_2 O3 1h max target(4Z-4Z) day_1 O3 8h max target(4Z-4Z) day_2 O3 8h max Select

Pacing strategy and VO2 kinetics during a 1500-m race.

PubMed

Hanon, C; Leveque, J-M; Thomas, C; Vivier, L

2008-03-01

We investigated the oxygen uptake response (V.O (2)) to a 1500-m test conducted using a competition race strategy. On an outdoor track, eleven middle-distance runners performed a test to determine V.O (2max), velocity associated with V.O (2max) (v-V.O (2max)) and a supramaximal 1500-m running test (each test at least two days apart). V.O (2max) response was measured with the use of a miniaturised telemetric gas exchange system (Cosmed, K4, Roma, Italy). The 1500-m running test was performed at a mean velocity of 107. 6 + 2 % v-V.O (2max). The maximal value of oxygen uptake recorded during the 1500-m test (V.O (2peak)) was reached by subjects at 75.9 + 7.5 s (mean + SD) (i.e., 459 +/- 59 m). The time to reach V.O (2max) (TV.O (2peak)) and the start velocity (200- to 400-m after the onset of the 1500 m) expressed in % v-V.O (2max) were negatively and significantly correlated (p < 0.05), but our results indicate that a fast start does not necessarily induce a good performance. These results suggest that V.O (2max) is reached by all the subjects at the onset of a simulated 1500-m running event and are therefore in contrast with previous results obtained during treadmill running.

[Evolution of breathing pattern and ventilation at maximal exercise during growth. Definition of reference values].

PubMed

Prioux, J; Mercier, J; Ramonatxo, M; Granier, P; Mercier, B; Prefaut, C

1995-01-01

The aim of the study was to define the changes of parameters of breathing pattern and ventilation (VE) as a function of age during maximal exercise in children. A multi-longitudinal survey was conducted in forty four untrained schoolboys, divided in three groups with initial age of 11.2 years for group I, 12.9 years for group II, and 14.9 for group III. These children were subsequently followed three years ago at the same period. The range age was thus 11.2 to 16.9 years. This study showed that, during growth, ventilation (VE max), tidal volume (VT max) and mean inspiratory flow (VT/TI max) increased significantly with age, that inspiratory frequency (f max) decreased, that inspiratory, expiratory and total time of the respiratory cycle (TI max, TE max, TTOT max) increased slightly and that the inspiration fraction (TI/TTOT max) was identical at 11 and 17 years. Furthermore we observed that the peak height velocity and peak tidal volume velocity took place at the same age, i.e., 14 years and that those of weight and VT/TI at the same age of 15 years. In conclusion, this study allowed us to define reference values for breathing pattern at maximal exercise in sedentary boys and to specify the relation between growth and parameters of breathing pattern in these children.

Physical activity enhances metabolic fitness independently of cardiorespiratory fitness in marathon runners.

PubMed

Laye, M J; Nielsen, M B; Hansen, L S; Knudsen, T; Pedersen, B K

2015-01-01

High levels of cardiovascular fitness (CRF) and physical activity (PA) are associated with decreased mortality and risk to develop metabolic diseases. The independent contributions of CRF and PA to metabolic disease risk factors are unknown. We tested the hypothesis that runners who run consistently >50 km/wk and/or >2 marathons/yr for the last 5 years have superior metabolic fitness compared to matched sedentary subjects (CRF, age, gender, and BMI). Case-control recruitment of 31 pairs of runner-sedentary subjects identified 10 matched pairs with similar VO2max (mL/min/kg) (similar-VO2max). The similar-VO2max group was compared with a group of age, gender, and BMI matched pairs who had the largest difference in VO2max (different-VO2max). Primary outcomes that defined metabolic fitness including insulin response to an oral glucose tolerance test, fasting lipids, and fasting insulin were superior in runners versus sedentary controls despite similar VO2max. Furthermore, performance (velocity at VO2max, running economy), improved exercise metabolism (lactate threshold), and skeletal muscle levels of mitochondrial proteins were superior in runners versus sedentary controls with similar VO2max. In conclusion subjects with a high amount of PA have more positive metabolic health parameters independent of CRF. PA is thus a good marker against metabolic diseases.

Physical Activity Enhances Metabolic Fitness Independently of Cardiorespiratory Fitness in Marathon Runners

PubMed Central

Laye, M. J.; Nielsen, M. B.; Hansen, L. S.; Knudsen, T.; Pedersen, B. K.

2015-01-01

High levels of cardiovascular fitness (CRF) and physical activity (PA) are associated with decreased mortality and risk to develop metabolic diseases. The independent contributions of CRF and PA to metabolic disease risk factors are unknown. We tested the hypothesis that runners who run consistently >50 km/wk and/or >2 marathons/yr for the last 5 years have superior metabolic fitness compared to matched sedentary subjects (CRF, age, gender, and BMI). Case-control recruitment of 31 pairs of runner-sedentary subjects identified 10 matched pairs with similar VO2max (mL/min/kg) (similar-VO2max). The similar-VO2max group was compared with a group of age, gender, and BMI matched pairs who had the largest difference in VO2max (different-VO2max). Primary outcomes that defined metabolic fitness including insulin response to an oral glucose tolerance test, fasting lipids, and fasting insulin were superior in runners versus sedentary controls despite similar VO2max. Furthermore, performance (velocity at VO2max, running economy), improved exercise metabolism (lactate threshold), and skeletal muscle levels of mitochondrial proteins were superior in runners versus sedentary controls with similar VO2max. In conclusion subjects with a high amount of PA have more positive metabolic health parameters independent of CRF. PA is thus a good marker against metabolic diseases. PMID:25821340

Effect of wine and vinegar processing of Rhizoma Corydalis on the tissue distribution of tetrahydropalmatine, protopine and dehydrocorydaline in rats.

PubMed

Dou, Zhiying; Li, Kefeng; Wang, Ping; Cao, Liu

2012-01-18

Vinegar and wine processing of medicinal plants are two traditional pharmaceutical techniques which have been used for thousands of years in China. Tetrahydropalmatine (THP), dehydrocorydaline (DHC) and protopine are three major bioactive molecules in Rhizoma Corydalis. In this study, a simple and reliable HPLC method was developed for simultaneous analysis of THP, DHC and protopine in rat tissues after gastric gavage administration of Rhizoma Corydalis. The validated HPLC method was successfully applied to investigate the effect of wine and vinegar processing on the compounds' distribution in rat tissues. Our results showed that processing mainly affect the T(max) and mean residence time (MRT) of the molecules without changing their C(max) and AUC(0-24)( )(h) Vinegar processing significantly increased the T(max) of DHC in heart, kidney, cerebrum, cerebrellum, brain stem and striatum and prolonged the T(max) of protopine in brain. No significant changes were observed on the T(max) of THP in rat tissues after vinegar processing. Wine processing reduced the T(max) of protopine and DHC in liver and spleen and T(max) of protopine in lung, but increased the T(max) of THP in all the rat tissues examined. To our knowledge, this is the first report on the effects of processing on the tissue distribution of the bioactive molecules from Rhizoma Corydalis.

Preface to the Focus Issue: chaos detection methods and predictability.

PubMed

Gottwald, Georg A; Skokos, Charalampos

2014-06-01

This Focus Issue presents a collection of papers originating from the workshop Methods of Chaos Detection and Predictability: Theory and Applications held at the Max Planck Institute for the Physics of Complex Systems in Dresden, June 17-21, 2013. The main aim of this interdisciplinary workshop was to review comprehensively the theory and numerical implementation of the existing methods of chaos detection and predictability, as well as to report recent applications of these techniques to different scientific fields. The collection of twelve papers in this Focus Issue represents the wide range of applications, spanning mathematics, physics, astronomy, particle accelerator physics, meteorology and medical research. This Preface surveys the papers of this Issue.

Search for P-ODD asymmetry in the radiative cross-section of the interaction of neutrons with lead nuclei

NASA Astrophysics Data System (ADS)

Gledenov, Yu. M.; Nesvizhevsky, V. V.; Sedyshev, P. V.; Shul'gina, E. V.; Vesna, V. A.

2014-03-01

The P-odd effect in the radiation cross section of capture of longitudinally polarized neutrons in a sample of natural lead is measured. The experiment was performed at PF1B facility at the Institut Max von Laue-Paul Langevin. The neutron polarization P n was 92%, the total flux of polarized neutrons was ˜3 × 1010 n/s, and the mean neutron wavelength was λ = 4.7 Å. Taking into account "0-test" we estimated the asymmetry: a γ(natPb) = (2.3 ± 3.5) × 10-7, i.e., α γ ≤ 8.1 × 10-7 at 90% confidence level.

Coordinated observations of PHEMU at radio wavelengths.

NASA Astrophysics Data System (ADS)

Pluchino, S.; Schillirò, F.; Salerno, E.; Pupillo, G.; Kraus, A.; Mack, K.-H.

We present preliminary results for our study of mutual phenomena of the Galilean satellites performed at radio wavelengths with the Medicina and Noto antennas of the Istituto di Radioastronomia \\textendash{} INAF, and with the Effelsberg 100-m radio telescope of the Max-Planck-Institute for Radioastronomy. Measurements of the radio flux density variation occurred during the mutual occultations of Io by Europa and Ganymede were carried out during the PHEMU09 campaign at K- and Q-band. Flux density variations observed for the first time at radio wavelengths are consistent with the typical optical patterns measured when partial occultations occurred. The flux density drops indicate a non-linear dependence with the percentage of overlapped area.

Very short (15s-15s) interval-training around the critical velocity allows middle-aged runners to maintain VO2 max for 14 minutes.

PubMed

Billat, V L; Slawinksi, J; Bocquet, V; Chassaing, P; Demarle, A; Koralsztein, J P

2001-04-01

The purpose of this study was to compare the effectiveness of three very short interval training sessions (15-15 s of hard and easier runs) run at an average velocity equal to the critical velocity to elicit VO2 max for more than 10 minutes. We hypothesized that the interval with the smallest amplitude (defined as the ratio between the difference in velocity between the hard and the easy run divided by the average velocity and multiplied by 100) would be the most efficient to elicit VO2 max for the longer time. The subjects were middle-aged runners (52 +/- 5 yr, VO2 max of 52.1 +/- 6 mL x min(-1) x kg(-1), vVO2 max of 15.9 +/- 1.8 km x h(-1), critical velocity of 85.6 +/- 1.2% vVO2 max) who were used to long slow distance-training rather than interval training. They performed three interval-training (IT) sessions on a synthetic track (400 m) whilst breathing through the COSMED K4b2 portable metabolic analyser. These three IT sessions were: A) 90-80% vVO2 max (for hard bouts and active recovery periods, respectively), the amplitude= (90-80/85) 100=11%, B) 100-70% vVO2 max amplitude=35%, and C) 60 x 110% vVO2 max amplitude = 59%. Interval training A and B allowed the athlete to spend twice the time at VO2 max (14 min vs. 7 min) compared to interval training C. Moreover, at the end of interval training A and B the runners had a lower blood lactate than after the procedure C (9 vs. 11 mmol x l(-1)). In conclusion, short interval-training of 15s-15s at 90-80 and 100-70% of vVO2 max proved to be the most efficient in stimulating the oxygen consumption to its highest level in healthy middle-aged long-distance runners used to doing only long slow distance-training.

Combined effects of inspired oxygen, carbon dioxide, and carbon monoxide on oxygen transport and aerobic capacity.

PubMed

Crocker, George H; Toth, Balazs; Jones, James H

2013-09-01

We hypothesized that breathing hypoxic, hypercapnic, and CO-containing gases together reduces maximal aerobic capacity (Vo2max) as the sum of each gas' individual effect on Vo2max. To test this hypothesis, goats breathed combinations of inspired O2 fraction (FiO2) of 0.06-0.21 and inspired CO2 fraction of 0.00 or 0.05, with and without inspired CO that elevated carboxyhemoglobin fraction (FHbCO) to 0.02-0.45, while running on a treadmill at speeds eliciting Vo2max. Individually, hypoxia and elevated FHbCO decreased fractional Vo2max (FVo2max, fraction of a goat's Vo2max breathing air) in linear, dose-dependent manners; hypercapnia did not change Vo2max. Concomitant hypoxia and elevated FHbCO decreased Vo2max less than the individual gas effects summed, indicating their combined effects on Vo2max are attenuated, fitting the following regression: FVo2max = 4.24 FiO2 + 0.519 FHbCO - 8.22 (FiO2 × FHbCO) + 0.117, (R(2) = 0.965, P < 0.001). The FVo2max correlated highly with total cardiopulmonary O2 delivery, not peripheral diffusing capacity, and with arterial O2 concentration (CaO2), not cardiac output. Hypoxia and elevated FHbCO decreased CaO2 by different mechanisms: hypoxia decreased arterial O2 saturation (SaO2), whereas elevated FHbCO decreased O2 capacitance {concentration of hemoglobin (Hb) available to bind O2 ([Hbavail])}. When breathing hypoxic gas (FiO2 0.12), CaO2 did not change with increasing FHbCO up to 0.30 because higher SaO2 of Hbavail offset decreased [Hbavail] due to the following: 1) hyperventilation with hypoxia and/or elevated FHbCO; 2) increased Hb affinity for O2 due to both Bohr and direct carboxyhemoglobin effects; and 3) the sigmoid relationship between O2 saturation and partial pressure elevating SaO2 more with hypoxia than normoxia.

Predicting Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer with Textural Features Derived from Pretreatment 18F-FDG PET/CT Imaging.

PubMed

Beukinga, Roelof J; Hulshoff, Jan B; van Dijk, Lisanne V; Muijs, Christina T; Burgerhof, Johannes G M; Kats-Ugurlu, Gursah; Slart, Riemer H J A; Slump, Cornelis H; Mul, Véronique E M; Plukker, John Th M

2017-05-01

Adequate prediction of tumor response to neoadjuvant chemoradiotherapy (nCRT) in esophageal cancer (EC) patients is important in a more personalized treatment. The current best clinical method to predict pathologic complete response is SUV max in 18 F-FDG PET/CT imaging. To improve the prediction of response, we constructed a model to predict complete response to nCRT in EC based on pretreatment clinical parameters and 18 F-FDG PET/CT-derived textural features. Methods: From a prospectively maintained single-institution database, we reviewed 97 consecutive patients with locally advanced EC and a pretreatment 18 F-FDG PET/CT scan between 2009 and 2015. All patients were treated with nCRT (carboplatin/paclitaxel/41.4 Gy) followed by esophagectomy. We analyzed clinical, geometric, and pretreatment textural features extracted from both 18 F-FDG PET and CT. The current most accurate prediction model with SUV max as a predictor variable was compared with 6 different response prediction models constructed using least absolute shrinkage and selection operator regularized logistic regression. Internal validation was performed to estimate the model's performances. Pathologic response was defined as complete versus incomplete response (Mandard tumor regression grade system 1 vs. 2-5). Results: Pathologic examination revealed 19 (19.6%) complete and 78 (80.4%) incomplete responders. Least absolute shrinkage and selection operator regularization selected the clinical parameters: histologic type and clinical T stage, the 18 F-FDG PET-derived textural feature long run low gray level emphasis, and the CT-derived textural feature run percentage. Introducing these variables to a logistic regression analysis showed areas under the receiver-operating-characteristic curve (AUCs) of 0.78 compared with 0.58 in the SUV max model. The discrimination slopes were 0.17 compared with 0.01, respectively. After internal validation, the AUCs decreased to 0.74 and 0.54, respectively. Conclusion: The predictive values of the constructed models were superior to the standard method (SUV max ). These results can be considered as an initial step in predicting tumor response to nCRT in locally advanced EC. Further research in refining the predictive value of these models is needed to justify omission of surgery. © 2017 by the Society of Nuclear Medicine and Molecular Imaging.

Effect of BMI, Body Fat Percentage and Fat Free Mass on Maximal Oxygen Consumption in Healthy Young Adults.

PubMed

Mondal, Himel; Mishra, Snigdha Prava

2017-06-01

Maximal oxygen consumption (VO 2max ) is an important measure of cardiorespiratory capacity of an individual at a given degree of fitness and oxygen availability. Risk of cardiovascular diseases increases with increasing degree of obesity and a low level of VO 2max has been established as an independent risk factor for cardiovascular mortality. To determine VO 2max in young adults and to find its correlation with Body Mass Index (BMI), Body Fat% and Fat Free Mass (FFM). Fifty four (male=30, female=24) healthy young adults of age group18-25 years after screening by Physical Activity Readiness Questionnaire (PAR-Q) participated in the study. Height was measured by stadiometer. Weight was measured by digital weighing scale with 0.1 kg sensitivity. Body fat% was measured by Bioelectrical Impedance Analysis (BIA) method. FFM was calculated by subtracting fat mass from the body weight. VO 2max (mL.kg -1 .min -1 ) was obtained by Submaximal Exercise Test (SET) by first two stages of Bruce Protocol with the basis of linear relationship between Heart Rate (HR) and oxygen consumption (VO 2 ). Data were analysed statistically in GraphPad Prism software version 6.01 for windows. VO 2max (mL.kg -1 .min -1 ) of male (43.25±7.25) was significantly (p<0.001) higher than female (31.65±2.10). BMI showed weak negative correlation (r= -0.3232, p=0.0171) with VO 2max but Body Fat% showed strong negative correlation (r= -0.7505, p<0.001) with VO 2max . FFM positively correlated (r=0.3727, p=0.0055) with VO 2max . Increased body fat is associated with decreased level of VO 2max in young adults. Obesity in terms of Fat% is a better parameter than BMI for prediction of low VO 2max .

Prognostic value of pre-treatment 18F-FDG PET uptake for nasopharyngeal carcinoma.

PubMed

Aktan, Meryem; Kanyilmaz, Gul; Yavuz, Berrin Benli; Koc, Mehmet; Eryılmaz, Mehmet Akif; Adli, Mustafa

2017-11-25

To evaluate the prognostic value of maximal standardized uptake values (SUV max ) from serial fluor-18-fluorodeoxyglucose positron emission tomography/computed tomography ( 18 F-FDG PET/CT) in patients with nasopharyngeal carcinoma (NPC). Fifty-two patients with NPC who underwent 18 F-FDG PET/CT scan before radiotherapy with/without chemotherapy were reviewed retrospectively. Twenty-seven patients (52%) were applied 3-D conformal radiotherapy and 25 patients (48%) applied intensity-modulated radiotherapy (IMRT). Fourteen (27%) patients were given neoadjuvant chemotherapy and forty-four (84.6%) patients were given concomitant and adjuvant chemotherapy. Median follow-up time was 34 months (range 5.6-66.4 months). Forty-four (84.6%) patients were alive at last follow-up and eight (15.4%) had died. The best cut-off value of the SUV max for the primary tumor site (SUV max -PT) was 13 and 9 for the lymph nodes (SUV max -LN). Patients with SUV max -PT ≥ 13.0 and SUV max -LN ≥ 9 had a significantly higher risk for the development of the distant metastases (p = 0.044 and p = 0.038). DFS was affected in patients with SUV max -PT ≥ 13 (log rank χ 2  = 2.54, p = 0.017) and was significantly lower in patients with SUV max -LN ≥ 9 for the lymph nodes (log rank χ 2  = 5.81, p = 0.013). OS was not affected by SUV levels. A multivariate Cox proportional hazard model of DFS included age (≥ 40), SUV max -LN (< 9), T stage (T1-2) and neoadjuvant chemotherapy are significantly better prognosis for the DFS. 18 F-FDG PET/CT uptake before treatment, as determined by SUV max , may be a valuable tool to evaluate prognosis in NPC patients.

Dose-response relationship of cardiorespiratory fitness adaptation to controlled endurance training in sedentary older adults.

PubMed

Huang, Guoyuan; Wang, Ru; Chen, Peijie; Huang, Sunny C; Donnelly, Joseph E; Mehlferber, Jon P

2016-03-01

The purpose of this investigation was to identify a quantitative dose-response relationship for enhancing maximal oxygen consumption (VO2max) in healthy sedentary older adults after controlled endurance training. This meta-analysis of controlled clinical trials included 1257 exercisers and 845 controls with a mean age of 67.45 ± 5.25 years. Effect sizes were calculated for training-induced VO2max changes. Different training regimens were analyzed and compared. The weighted net change of the mean VO2max values showed a significant increase of 3.78 ml/kg per min (95% confidence interval = 3.29 to 4.27; p < 0.0001) in response to aerobic training. Interstudy differences in VO2max changes were significantly related to exercise intensity, and explained approximately 11% of the variance of the VO2max responses. VO2max improved significantly at 35%-50% heart rate reserve (HRR) and continued improving at a greater rate with increasing "dose". The largest VO2max-improvement adaptation was achieved with a mean intensity of 66%-73% HRR. The magnitudes of the VO2max adaptation are identical to exercise at 57%-65% HRR and at 75%-80% HRR. Higher intensity doses more than 75-80% HRR did not lead to greater enhancement of VO2max improvements but, conversely, resulted in large declines. Our data provide quantitative insight into the magnitude of VO2max alterations as affected by exercise intensity, duration, frequency, and program length. The shapes of the dose-response curves are not simply linear, but with many similar trends and noteworthy characteristics. Aerobic training at a mean intensity of 66%-73% HRR with 40-50 min per session for 3-4 day/week for 30-40 weeks appears to be effective and optimal for maximum cardiorespiratory benefits in healthy sedentary older adults. © The European Society of Cardiology 2015.

An alternative method to estimate zero flow temperature differences for Granier's thermal dissipation technique.

PubMed

Regalado, Carlos M; Ritter, Axel

2007-08-01

Calibration of the Granier thermal dissipation technique for measuring stem sap flow in trees requires determination of the temperature difference (DeltaT) between a heated and an unheated probe when sap flow is zero (DeltaT(max)). Classically, DeltaT(max) has been estimated from the maximum predawn DeltaT, assuming that sap flow is negligible at nighttime. However, because sap flow may continue during the night, the maximum predawn DeltaT value may underestimate the true DeltaT(max). No alternative method has yet been proposed to estimate DeltaT(max) when sap flow is non-zero at night. A sensitivity analysis is presented showing that errors in DeltaT(max) may amplify through sap flux density computations in Granier's approach, such that small amounts of undetected nighttime sap flow may lead to large diurnal sap flux density errors, hence the need for a correct estimate of DeltaT(max). By rearranging Granier's original formula, an optimization method to compute DeltaT(max) from simultaneous measurements of diurnal DeltaT and micrometeorological variables, without assuming that sap flow is negligible at night, is presented. Some illustrative examples are shown for sap flow measurements carried out on individuals of Erica arborea L., which has needle-like leaves, and Myrica faya Ait., a broadleaf species. We show that, although DeltaT(max) values obtained by the proposed method may be similar in some instances to the DeltaT(max) predicted at night, in general the values differ. The procedure presented has the potential of being applied not only to Granier's method, but to other heat-based sap flow systems that require a zero flow calibration, such as the Cermák et al. (1973) heat balance method and the T-max heat pulse system of Green et al. (2003).

Familial aggregation of VO(2max) response to exercise training: results from the HERITAGE Family Study.

PubMed

Bouchard, C; An, P; Rice, T; Skinner, J S; Wilmore, J H; Gagnon, J; Pérusse, L; Leon, A S; Rao, D C

1999-09-01

The aim of this study was to test the hypothesis that individual differences in the response of maximal O(2) uptake (VO(2max)) to a standardized training program are characterized by familial aggregation. A total of 481 sedentary adult Caucasians from 98 two-generation families was exercise trained for 20 wk and was tested for VO(2max) on a cycle ergometer twice before and twice after the training program. The mean increase in VO(2max) reached approximately 400 ml/min, but there was considerable heterogeneity in responsiveness, with some individuals experiencing little or no gain, whereas others gained >1.0 l/min. An ANOVA revealed that there was 2.5 times more variance between families than within families in the VO(2max) response variance. With the use of a model-fitting procedure, the most parsimonious models yielded a maximal heritability estimate of 47% for the VO(2max) response, which was adjusted for age and sex with a maternal transmission of 28% in one of the models. We conclude that the trainability of VO(2max) is highly familial and includes a significant genetic component.

1H line width dependence on MAS speed in solid state NMR - Comparison of experiment and simulation

NASA Astrophysics Data System (ADS)

Sternberg, Ulrich; Witter, Raiker; Kuprov, Ilya; Lamley, Jonathan M.; Oss, Andres; Lewandowski, Józef R.; Samoson, Ago

2018-06-01

Recent developments in magic angle spinning (MAS) technology permit spinning frequencies of ≥100 kHz. We examine the effect of such fast MAS rates upon nuclear magnetic resonance proton line widths in the multi-spin system of β-Asp-Ala crystal. We perform powder pattern simulations employing Fokker-Plank approach with periodic boundary conditions and 1H-chemical shift tensors calculated using the bond polarization theory. The theoretical predictions mirror well the experimental results. Both approaches demonstrate that homogeneous broadening has a linear-quadratic dependency on the inverse of the MAS spinning frequency and that, at the faster end of the spinning frequencies, the residual spectral line broadening becomes dominated by chemical shift distributions and susceptibility effects even for crystalline systems.

Instantaneous and scale-versatile gourdron theory: pair momentum equation, quasi-stability concept, and statistical indeterminacy revealing masses of elementary, bio-molecular, and cosmic particles

NASA Astrophysics Data System (ADS)

Naitoh, Ken

2014-04-01

Flexible particles, including hadrons, atoms, hydrated biological molecules, cells, organs containing water, liquid fuel droplets in engines, and stars commonly break up after becoming a gourd shape rather than that of a string; this leads to cyto-fluid dynamics that can explain the proliferation, differentiation, and replication of biomolecules, onto-biology that clarifies the relationship between information, structure, and function, and the gourd theory that clarifies masses, including quark-leptons and Plank energy. The masses are related to the super-magic numbers, including the asymmetric silver ratio and symmetric yamato ratio, and reveal further mechanisms underlying symmetry breaking. This paper gives further theoretical basis and evidence, because the gourd theory reported previously is a little analogical and instinctive.

Feasibility of Onboard Processing of Heuristic Path Planning and Navigation Algorithms within SUAS Autopilot Computational Constraints

DTIC Science & Technology

2014-03-01

brake_group > NONE </ brake_group > <retractable>0</retractable> </contact> <contact type="BOGEY" name="RIGHT_MLG...damping_coeff> <max_steer unit="DEG"> 0.0 </max_steer> < brake_group > NONE </ brake_group > <retractable>0</retractable...damping_coeff unit="LBS/FT/SEC"> 100 </damping_coeff> <max_steer unit="DEG"> 360.0 </max_steer> < brake_group > NONE

Registration of cytoplasmic male-sterile oilseed sunflower genetic stocks CMS GIG2 and CMS GIG2-RV, and fertility restoration lines RF GIG2-MAX 1631 and RF GIG2-MAX 1631-RV

USDA-ARS?s Scientific Manuscript database

Two cytoplasmic male-sterile (CMS) oilseed sunflower (Helianthus annuus L.) genetic stocks, CMS GIG2 (Reg. No. xxx, PI xxxx), and CMS GIG2-RV (Reg. No. xxx, PI xxxx), and corresponding fertility restoration lines RF GIG2-MAX 1631 (Reg. No. xxx, PI xxxx) and RF GIG2-MAX 1631-RV (Reg. No. xxx, PI xxx...

Advanced nickel base alloys for high strength, corrosion applications

DOEpatents

Flinn, John E.

1998-01-01

Improved nickel-base alloys of enhanced strength and corrosion resistance, produced by atomization of an alloy melt under an inert gas atmosphere and of composition 0-20Fe, 10-30Cr, 2-12Mo, 6 max. Nb, 0.05-3 V, 0.08 max. Mn, 0.5 max. Si, less than 0.01 each of Al and Ti, less than 0.05 each of P and S, 0.01-0.08C, less than 0.2N, 0.1 max. 0, bal. Ni.

Advanced nickel base alloys for high strength, corrosion applications

DOEpatents

Flinn, J.E.

1998-11-03

Improved nickel-base alloys of enhanced strength and corrosion resistance, produced by atomization of an alloy melt under an inert gas atmosphere and of composition 0--20Fe, 10--30Cr, 2--12Mo, 6 max. Nb, 0.05--3 V, 0.08 max. Mn, 0.5 max. Si, less than 0.01 each of Al and Ti, less than 0.05 each of P and S, 0.01--0.08C, less than 0.2N, 0.1 max. 0, bal. Ni. 3 figs.

Sleep quality and duration are associated with performance in maximal incremental test.

PubMed

Antunes, B M; Campos, E Z; Parmezzani, S S; Santos, R V; Franchini, E; Lira, F S

2017-08-01

Inadequate sleep patterns may be considered a trigger to development of several metabolic diseases. Additionally, sleep deprivation and poor sleep quality can negatively impact performance in exercise training. However, the impact of sleep duration and sleep quality on performance during incremental maximal test performed by healthy men is unclear. Therefore, the purpose of the study was to analyze the association between sleep pattern (duration and quality) and performance during maximal incremental test in healthy male individuals. A total of 28 healthy males volunteered to take part in the study. Sleep quality, sleep duration and physical activity were subjectively assessed by questionnaires. Sleep pattern was classified by sleep duration (>7h or <7h of sleep per night) and sleep quality according to the sum of measured points and/or scores by the Pittsburgh Sleep Quality Index (PSQI). Incremental exercise test was performed at 35 watts for untrained subjects, 70 watts for physically active subjects and 105 watts for well-trained subjects. HR max was correlated with sleep quality (r=0.411, p=0.030) and sleep duration (r=-0.430, p=0.022). Participants reporting good sleep quality presented higher values of W max , VO 2max and lower values of HR max when compared to participants with altered sleep. Regarding sleep duration, only W max was influenced by the amount of sleeping hours per night and this association remained significant even after adjustment by VO 2max . Sleep duration and quality are associated, at least in part, with performance during maximal incremental test among healthy men, with losses in W max and HR max . In addition, our results suggest that the relationship between sleep patterns and performance, mainly in W max , is independent of fitness condition. Copyright © 2017 Elsevier Inc. All rights reserved.

VO2 attained during treadmill running: the influence of a specialist (400-m or 800-m) event.

PubMed

James, David V B; Sandals, Leigh E; Draper, Stephen B; Maldonado-Martin, Sara; Wood, Dan M

2007-06-01

Previously it has been observed that, in well-trained 800-m athletes, VO2max is not attained during middle-distance running events on a treadmill, even when a race-type pacing strategy is adopted. Therefore, the authors investigated whether specialization in a particular running distance (400-m or 800-m) influences the VO2 attained during running on a treadmill. Six 400-m and six 800-m running specialists participated in the study.A 400-m trial and a progressive test to determine VO2max were completed in a counterbalanced order. Oxygen uptakes attained during the 400-m trial were compared to examine the influence of specialist event. A VO2 plateau was observed in all participants for the progressive test, demonstrating the attainment of VO2max. The VO2max values were 56.2 +/- 4.7 and 69.3 +/- 4.5 mL x kg-1 x min-1 for the 400-m- and 800-m-event specialists, respectively (P = .0003). Durations for the 400-m trial were 55.1 +/- 4.2 s and 55.8 +/- 2.3 s for the 400-m- and 800-m-event specialists, respectively. The VO2 responses achieved were 93.1% +/- 2.0% and 85.7% +/- 3.0% VO2max for the 400-m- and 800-m-event specialists, respectively (P = .001). These results demonstrate that specialist running events do appear to influence the percentage of VO2max achieved in the 400-m trial, with the 800-m specialists attaining a lower percentage of VO2max than the 400-m specialists. The 400-m specialists appear to compensate for a lower VO2max by attaining a higher percentage VO2max during a 400-m trial.

Maximum home systolic blood pressure is a useful indicator of arterial stiffness in patients with type 2 diabetes mellitus: post hoc analysis of a cross-sectional multicenter study.

PubMed

Ushigome, Emi; Fukui, Michiaki; Hamaguchi, Masahide; Tanaka, Toru; Atsuta, Haruhiko; Mogami, Shin-ichi; Tsunoda, Sei; Yamazaki, Masahiro; Hasegawa, Goji; Nakamura, Naoto

2014-09-01

Maximum (max) home systolic blood pressure (HSBP) as well as mean HSBP or HSBP variability was reported to increase the predictive value of target organ damage. Yet, the association between max HSBP and target organ damage in patients with type 2 diabetes has never been reported. The aim of this study was to investigate the association between max HSBP and pulse wave velocity (PWV), a marker of arterial stiffness which in turn is a marker of target organ damage, in patients with type 2 diabetes. We assessed the relationship of mean HSBP or max HSBP to PWV, and compared area under the receiver-operating characteristic curve (AUC) of mean HSBP or max HSBP for arterial stiffness in 758 patients with type 2 diabetes. In the univariate analyses, age, duration of diabetes mellitus, body mass index, mean clinic systolic blood pressure (SBP), mean HSBP and max HSBP were associated with PWV. Multivariate linear regression analyses indicated that mean morning SBP (β=0.156, P=0.001) or max morning SBP (β=0.146, P=0.001) were significantly associated with PWV. AUC (95% CI) for arterial stiffness, defined as PWV equal to or more than 1800 cm per second, in mean morning SBP and max morning SBP were 0.622 (0.582-0.662; P<0.001) and 0.631 (0.591-0.670; P<0.001), respectively. Our findings implicate that max HSBP as well as mean HSBP was significantly associated with arterial stiffness in patients with type 2 diabetes. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Development of a Highly Efficient Hybrid White Organic-Light-Emitting Diode with a Single Emission Layer by Solution Processing.

PubMed

Wu, Jun-Yi; Chen, Show-An

2018-02-07

We use a mixed host, 2,6-bis[3-(carbazol-9-yl)phenyl]pyridine blended with 20 wt % tris(4-carbazoyl-9-ylphenyl)amine, to lower the hole-injection barrier, along with the bipolar and high-photoluminescence-quantum-yield (Φ p = 84%), blue thermally activated delay fluorescence (TADF) material of 9,9-dimethyl-9,10-dihydroacridine-2,4,6-triphenyl-1,3,5-triazine (DMAC-TRZ) as a blue dopant to compose the emission layer for the fabrication of a TADF blue organic-light-emitting diode (BOLED). The device is highly efficient with the following performance parameters: maximum brightness (B max ) = 57586 cd/m 2 , maximum current efficiency (CE max ) = 35.3 cd/A, maximum power efficiency (PE max ) = 21.4 lm/W, maximum external quantum efficiency (EQE max ) = 14.1%, and CIE coordinates (0.18, 0.42). This device has the best performance recorded among the reported solution-processed TADF BOLEDs and has a low efficiency roll-off: at brightness values of 1000 and 5000 cd/m 2 , its CEs are close, being 35.1 and 30.1 cd/A, respectively. Upon further doping of the red phosphor Ir(dpm)PQ 2 (emission peak λ max = 595 nm) into the blue emission layer, we obtained a TADF-phosphor hybrid white organic-light-emitting diode (T-P hybrid WOLED) with high performance: B max = 43594 cd/m 2 , CE max = 28.8 cd/A, PE max = 18.1 lm/W, and CIE coordinates (0.38, 0.44). This B max = 43594 cd/m 2 is better than that of the vacuum-deposited WOLED with a blue TADF emitter, 10000 cd/m 2 . This is also the first report on a T-P hybrid WOLED with a solution-processed emitting layer.

Relationship Between Post-exercise Heart Rate Recovery and Changing Ratio of Cardiopulmonary Exercise Capacity.

PubMed

Kim, Ji-Hyun; Choe, Yu-Ri; Song, Min-Keun; Choi, In-Sung; Han, Jae-Young

2017-12-01

To determine whether heart rate recovery (HRR) following an exercise tolerance test (ETT) is correlated with a changing ratio of peak oxygen consumption (VO 2 ) and maximal metabolic equivalents (MET max ). A total of 60 acute myocardial infarction (AMI) patients who underwent ETT at both assessment points - 3 weeks (T0) after the AMI attack and 3 months after T0 (T1) were included. After achieving a peak workload, the treadmill was stopped with a 5-minute cooldown period, and the patients recovered in a comfortable and relaxed seated position. HRR was defined as the difference between the maximal heart rate (HR max ) and the HR measured at specific time intervals - immediately after the cool down period (HRR-0) and 3 minutes after the completion of the ETT (HRR-3). HRR-0 and HRR-3 increased over time, whereas VO 2max and MET max did not show significant changes. There was a positive correlation between HRR at T0 and the exercise capacity at T0. HRR at T0 also showed a positive correlation with the exercise capacity at T1. There was no significant correlation between HRR measured at T0 and the change in the ratio of VO 2max and MET max , as calculated by subtracting VO 2max and MET max obtained at T0 from those obtained at T1, divided by VO 2max at T0 and multiplied by 100. Post-exercise HRR measured at 3 weeks after the AMI onset can reflect the exercise capacity 3 months after the first ETT. However, it may be difficult to correlate post-exercise HRR at T0 with the degree of increase in cardiopulmonary exercise capacity in patients with AMI.

Cardiopulmonary fitness in a sample of Malaysian population.

PubMed

Singh, R; Singh, H J; Sirisinghe, R G

1989-01-01

Lung capacity and maximum oxygen uptake (VO2max) were measured directly in 167 healthy males, from all the main races in Malaysia. Their ages ranged from 13 to 59 years. They were divided into five age groups (A to E), ranging from the second to the sixth decade. Lung capacities were determined using a dry spirometer and VO2max was taken as the maximum rate of oxygen consumption during exhaustive exercise on a cycle ergometer. Mean forced vital capacity (FVC) was 3.3 +/- 0.5 l and it correlated negatively with age. Mean VO2max was 3.2 +/- 0.2 l.min-1 (56.8 +/- 3.5 ml.kg-1.min-1) in Group A (13-19 years) compared to 1.7 +/- 0.2 l.min-1 (28.9 +/- 2.9 ml.kg-1.min-1) in Group E (50-59 years). Regression analysis revealed an age-related decline in VO2max of 0.77 ml.kg-1.min-1.year-1. Multiple regression of the data gave the following equations for the prediction of an individual's VO2max: VO2max (l.min-1) = 1.99 + 0.035 (weight)-0.04 (age), VO2max (ml.kg-1.min-1) = 67.7-0.77 (age), where age is in years, weight in kg. In terms of VO2max as an index of cardiopulmonary performance. Malaysians have a relatively lower capacity when related to the Swedish norms or even to those of some Chilean workers. Malaysians were, however, within the average norms of the American Heart Association's recommendations. Age-related decline in VO2max was also somewhat higher in the Malaysians.

F-amplitude, left atrial appendage velocity, and thromboembolic risk in nonrheumatic atrial fibrillation. Stroke Prevention in Atrial Fibrillation Investigators.

PubMed

Blackshear, J L; Safford, R E; Pearce, L A

1996-04-01

Reduced left atrial appendage velocity (LAAV) has been identified as a marker for thromboembolism in patients with atrial fibrillation. It was postulated that electrocardiographic (ECG) F-wave amplitude would correlate with LAAV, and inversely with the risk of thromboembolism in patients with atrial fibrillation. In all, 53 patients with nonrheumatic (NRAF) and 7 patients with rheumatic (RAF) atrial fibrillation underwent assessment of maximum LAAV, which was correlated to the maximum ECG F-wave voltage from lead V1 (F(max)). In 450 NRAF patients on neither aspirin nor warfarin, the relationship between F(max) and thromboembolic risk was assessed over an average follow-up of 1.3 years. F(max) did not correlate with LAAV (r = 0.2, p = 0.07). Patients with intermittent atrial fibrillation (n = 123) had smaller F(max) amplitude than patients with constant atrial fibrillation (n = 327) (mean 0.73 vs. 0.88 mV-1, p = 0.001). F(max) amplitude was not related to a history of hypertension, systolic blood pressure, duration of NRAF, abnormal transthoracic echocardiographic left ventricular (LV) systolic function or left atrial (LA) diameter. There was a strong trend for increased LV mass being related to smaller F(max) amplitude after adjusting for body surface area (p = 0.06). F(max) amplitude was not correlated with risk of embolic events, including only those events presumed by a panel of case-blinded neurologists to be cardioembolic. F(max) amplitude in NRAF is smaller in patients with intermittent versus constant AF. It does not correlate with LAAV, LA size, increased LV mass, or systolic dysfunction, hypertension, or risk of embolism. Therefore, F(max) amplitude may not be used as a surrogate for LAAV, or as a measure of thromboembolic risk in NRAF.

Change in VO2max and time trial performance in response to high-intensity interval training prescribed using ventilatory threshold.

PubMed

Astorino, Todd A; deRevere, Jamie; Anderson, Theodore; Kellogg, Erin; Holstrom, Patrick; Ring, Sebastian; Ghaseb, Nicholas

2018-06-19

Completion of high-intensity interval training (HIIT) leads to significant increases in maximal oxygen uptake (VO 2max ) and oxidative capacity. However, individual responses to HIIT have been identified as approximately 20-40% of individuals show no change in VO 2max , which may be due to the relatively homogeneous approach to implementing HIIT. This study tested the effects of HIIT prescribed using ventilatory threshold (VT) on changes in VO 2max and cycling performance. Fourteen active men and women (age and VO 2max  = 27 ± 8 year and 38 ± 4 mL/kg/min) underwent nine sessions of HIIT, and 14 additional men and women (age and VO 2max  = 22 ± 3 year and 40 ± 5 mL/kg/min) served as controls. Training was performed on a cycle ergometer at a work rate equal to 130%VT and consisted of eight to ten 1 min bouts interspersed with 75 s of recovery. At baseline and post-testing, they completed progressive cycling to exhaustion to determine VO 2max , and on a separate day, a 5 mile cycling time trial. Compared to the control group, HIIT led to significant increases in VO 2max (6%, p = 0.007), cycling performance (2.5%, p = 0.003), and absolute VT (9 W, p = 0.005). However, only 57% of participants revealed meaningful increases in VO 2max and cycling performance in response to training, and two showed no change in either outcome. A greater volume of HIIT may be needed to maximize the training response for all individuals.

Respiratory muscle dysfunction in congestive heart failure: clinical correlation and prognostic significance.

PubMed

Meyer, F J; Borst, M M; Zugck, C; Kirschke, A; Schellberg, D; Kübler, W; Haass, M

2001-05-01

In congestive heart failure (CHF), the prognostic significance of impaired respiratory muscle strength has not been established. Maximal inspiratory pressure (Pi(max)) was prospectively determined in 244 consecutive patients (207 men) with CHF (ischemic, n=75; idiopathic dilated cardiomyopathy, n=169; age, 54+/-11 years; left ventricular ejection fraction [LVEF], 22+/-10%). Pi(max) was lower in the 244 patients with CHF than in 25 control subjects (7.6+/-3.3 versus 10.5+/-3.7 kPa; P=0.001). The 57 patients (23%) who died during follow-up (23+/-16 months; range, 1 to 48 months) had an even more reduced Pi(max) (6.3+/-3.2 versus 8.1+/-3.2 kPa in survivors; P=0.001). Kaplan-Meier survival curves differentiated between patients subdivided according to quartiles for Pi(max) (P=0.014). Pi(max) was a strong risk predictor in both univariate (P=0.001) and multivariate Cox proportional hazard analyses (P=0.03); multivariate analyses also included NYHA functional class, LVEF, peak oxygen consumption (peak VO(2)), and norepinephrine plasma concentration. The areas under the receiver-operating characteristic curves for prediction of 1-year survival were comparable for Pi(max) and peak VO(2) (area under the curve [AUC], 0.68 versus 0.73; P=0.28), and they improved with the triple combination of Pi(max), peak VO(2), and LVEF (AUC, 0.82; P=0.004 compared with AUC of Pi(max)). In patients with CHF, inspiratory muscle strength is reduced and emerges as a novel, independent predictor of prognosis. Because testing for Pi(max) is simple in clinical practice, it might serve as an additional factor to improve risk stratification and patient selection for cardiac transplantation.

Maximum Oxygen Uptake During and After Long-Duration Space Flight

NASA Technical Reports Server (NTRS)

Moore, Alan D., Jr.; Evetts, Simon N.; Feiveson, Alan H.; Lee, Stuart M. C.; McCleary. Frank A.; Platts, Steven H.

2010-01-01

Decreased maximum oxygen consumption (VO2max) during and after space flight may impair a crewmember s ability to perform mission-critical work that is high intensity and/or long duration in nature (Human Research Program Integrated Research Plan Risk 2.1.2: Risk of Reduced Physical Performance Capabilities Due to Reduced Aerobic Capacity). When VO2max was measured in Space Shuttle experiments, investigators reported that it did not change during short-duration space flight but decreased immediately after flight. Similar conclusions, based on the heart rate (HR) response of Skylab crewmembers, were made previously concerning long-duration space flight. Specifically, no change in the in-flight exercise HR response in 8 of 9 Skylab crewmembers indicated that VO2max was maintained during flight, but the elevated exercise HR after flight indicated that VO2max was decreased after landing. More recently, a different pattern of in-flight exercise HR response, and assumed changes in VO2max, emerged from routine testing of International Space Station (ISS) crewmembers. Most ISS crewmembers experience an elevated in-flight exercise HR response early in their mission, with a gradual return toward preflight levels as the mission progresses. Similar to previous reports, exercise HR is elevated after ISS missions and returns to preflight levels by 30 days after landing. VO2max has not been measured either during or after long-duration space flight. The purposes of the ISS VO2max experiment are (1) to measure VO2max during and after long-duration spaceflight, and (2) to determine if submaximal exercise test results can be used to accurately estimate VO 2max.

Level-2 Milestone 4797: Early Users on Max, Sequoia Visualization Cluster

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cupps, Kim C.

This report documents the fact that an early user has run successfully on Max, the Sequoia visualization cluster, ASC L2 milestone 4797: Early Users on Sequoia Visualization System (Max), due December 31, 2013. The Max visualization and data analysis cluster will provide Sequoia users with compute cycles and an interactive option for data exploration and analysis. The system will be integrated in the first quarter of FY14 and the system is expected to be moved to the classified network by the second quarter of FY14. The goal of this milestone is to have early users running their visualization and datamore » analysis work on the Max cluster on the classified network.« less

75 FR 57456 - Light-Walled Rectangular Pipe and Tube from the People's Republic of China: Final Results of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-21

...'') U.S. affiliated importer FitMAX Inc. (``FitMAX'') on June 2, 2010 and June 16, 2010. FitMAX... carbon- quality light-walled steel pipe and tube, of rectangular (including square) cross section, having...

Development of formulae for estimating amylose content, amylopectin chain length distribution, and resistant starch content based on the iodine absorption curve of rice starch.

PubMed

Nakamura, Sumiko; Satoh, Hikaru; Ohtsubo, Ken'ichi

2015-01-01

Not only amylose but also amylopectin greatly affects the gelatinization properties of rice starch and the quality of cooked rice grains. We here characterized the starches of 32 rice cultivars and evaluated the relationship between their iodine absorption curve, apparent amylose content (AAC), pasting property, resistant starch (RS) content, and chain length distribution of amylopectin. We found that the iodine absorption curve differed among the various sample rice cultivars. Using the wavelength at which absorbance becomes maximum on iodine staining of starch (λmax), we propose a novel index, "new λmax" (AAC/(λmax of sample rice starches-λmax of glutinous rice starch)). We developed the novel estimation formulae for AAC, RS contents, and amylopectin fractions with the use of λmax and "new λmax." These formulae would lead to the improved method for estimating starch properties using an easy and rapid iodine colorimetric method.

Perspective: Maximum caliber is a general variational principle for dynamical systems

NASA Astrophysics Data System (ADS)

Dixit, Purushottam D.; Wagoner, Jason; Weistuch, Corey; Pressé, Steve; Ghosh, Kingshuk; Dill, Ken A.

2018-01-01

We review here Maximum Caliber (Max Cal), a general variational principle for inferring distributions of paths in dynamical processes and networks. Max Cal is to dynamical trajectories what the principle of maximum entropy is to equilibrium states or stationary populations. In Max Cal, you maximize a path entropy over all possible pathways, subject to dynamical constraints, in order to predict relative path weights. Many well-known relationships of non-equilibrium statistical physics—such as the Green-Kubo fluctuation-dissipation relations, Onsager's reciprocal relations, and Prigogine's minimum entropy production—are limited to near-equilibrium processes. Max Cal is more general. While it can readily derive these results under those limits, Max Cal is also applicable far from equilibrium. We give examples of Max Cal as a method of inference about trajectory distributions from limited data, finding reaction coordinates in bio-molecular simulations, and modeling the complex dynamics of non-thermal systems such as gene regulatory networks or the collective firing of neurons. We also survey its basis in principle and some limitations.

MaxBin 2.0: an automated binning algorithm to recover genomes from multiple metagenomic datasets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wu, Yu-Wei; Simmons, Blake A.; Singer, Steven W.

The recovery of genomes from metagenomic datasets is a critical step to defining the functional roles of the underlying uncultivated populations. We previously developed MaxBin, an automated binning approach for high-throughput recovery of microbial genomes from metagenomes. Here, we present an expanded binning algorithm, MaxBin 2.0, which recovers genomes from co-assembly of a collection of metagenomic datasets. Tests on simulated datasets revealed that MaxBin 2.0 is highly accurate in recovering individual genomes, and the application of MaxBin 2.0 to several metagenomes from environmental samples demonstrated that it could achieve two complementary goals: recovering more bacterial genomes compared to binning amore » single sample as well as comparing the microbial community composition between different sampling environments. Availability and implementation: MaxBin 2.0 is freely available at http://sourceforge.net/projects/maxbin/ under BSD license. Supplementary information: Supplementary data are available at Bioinformatics online.« less

Perspective: Maximum caliber is a general variational principle for dynamical systems.

PubMed

Dixit, Purushottam D; Wagoner, Jason; Weistuch, Corey; Pressé, Steve; Ghosh, Kingshuk; Dill, Ken A

2018-01-07

We review here Maximum Caliber (Max Cal), a general variational principle for inferring distributions of paths in dynamical processes and networks. Max Cal is to dynamical trajectories what the principle of maximum entropy is to equilibrium states or stationary populations. In Max Cal, you maximize a path entropy over all possible pathways, subject to dynamical constraints, in order to predict relative path weights. Many well-known relationships of non-equilibrium statistical physics-such as the Green-Kubo fluctuation-dissipation relations, Onsager's reciprocal relations, and Prigogine's minimum entropy production-are limited to near-equilibrium processes. Max Cal is more general. While it can readily derive these results under those limits, Max Cal is also applicable far from equilibrium. We give examples of Max Cal as a method of inference about trajectory distributions from limited data, finding reaction coordinates in bio-molecular simulations, and modeling the complex dynamics of non-thermal systems such as gene regulatory networks or the collective firing of neurons. We also survey its basis in principle and some limitations.

Blunted perception of neural respiratory drive and breathlessness in patients with cystic fibrosis.

PubMed

Reilly, Charles C; Jolley, Caroline J; Elston, Caroline; Moxham, John; Rafferty, Gerrard F

2016-01-01

The electromyogram recorded from the diaphragm (EMG di ) and parasternal intercostal muscle using surface electrodes (sEMG para ) provides a measure of neural respiratory drive (NRD), the magnitude of which reflects lung disease severity in stable cystic fibrosis. The aim of this study was to explore perception of NRD and breathlessness in both healthy individuals and patients with cystic fibrosis. Given chronic respiratory loading and increased NRD in cystic fibrosis, often in the absence of breathlessness at rest, we hypothesised that patients with cystic fibrosis would be able to tolerate higher levels of NRD for a given level of breathlessness compared to healthy individuals during exercise. 15 cystic fibrosis patients (mean forced expiratory volume in 1 s (FEV 1 ) 53.5% predicted) and 15 age-matched, healthy controls were studied. Spirometry was measured in all subjects and lung volumes measured in the cystic fibrosis patients. EMG di and sEMG para were recorded at rest and during incremental cycle exercise to exhaustion and expressed as a percentage of maximum (% max) obtained from maximum respiratory manoeuvres. Borg breathlessness scores were recorded at rest and during each minute of exercise. EMG di % max and sEMG para % max and associated Borg breathlessness scores differed significantly between healthy subjects and cystic fibrosis patients at rest and during exercise. The relationship between EMG di % max and sEMG para % max and Borg score was shifted to the right in the cystic fibrosis patients, such that at comparable levels of EMG di % max and sEMG para % max the cystic fibrosis patients reported significantly lower Borg breathlessness scores compared to the healthy individuals. At Borg score 1 (clinically significant increase in breathlessness from baseline) corresponding levels of EMG di % max (20.2±12% versus 32.15±15%, p=0.02) and sEMG para % max (18.9±8% versus 29.2±15%, p=0.04) were lower in the healthy individuals compared to the cystic fibrosis patients. In the cystic fibrosis patients EMG di % max at Borg score 1 was related to the degree of airways obstruction (FEV 1 ) (r=-0.664, p=0.007) and hyperinflation (residual volume/total lung capacity) (r=0.710, p=0.03). This relationship was not observed for sEMG para % max. These data suggest that compared to healthy individuals, patients with cystic fibrosis can tolerate much higher levels of NRD before increases in breathlessness from baseline become clinically significant. EMG di % max and sEMG para % max provide physiological tools with which to elucidate factors underlying inter-individual differences in breathlessness perception.

Sensitivity of C-Band Polarimetric Radar-Based Drop Size Distribution Measurements to Maximum Diameter Assumptions

NASA Technical Reports Server (NTRS)

Carey, Lawrence D.; Petersen, Walter A.

2011-01-01

The estimation of rain drop size distribution (DSD) parameters from polarimetric radar observations is accomplished by first establishing a relationship between differential reflectivity (Z(sub dr)) and the central tendency of the rain DSD such as the median volume diameter (D0). Since Z(sub dr) does not provide a direct measurement of DSD central tendency, the relationship is typically derived empirically from rain drop and radar scattering models (e.g., D0 = F[Z (sub dr)] ). Past studies have explored the general sensitivity of these models to temperature, radar wavelength, the drop shape vs. size relation, and DSD variability. Much progress has been made in recent years in measuring the drop shape and DSD variability using surface-based disdrometers, such as the 2D Video disdrometer (2DVD), and documenting their impact on polarimetric radar techniques. In addition to measuring drop shape, another advantage of the 2DVD over earlier impact type disdrometers is its ability to resolve drop diameters in excess of 5 mm. Despite this improvement, the sampling limitations of a disdrometer, including the 2DVD, make it very difficult to adequately measure the maximum drop diameter (D(sub max)) present in a typical radar resolution volume. As a result, D(sub max) must still be assumed in the drop and radar models from which D0 = F[Z(sub dr)] is derived. Since scattering resonance at C-band wavelengths begins to occur in drop diameters larger than about 5 mm, modeled C-band radar parameters, particularly Z(sub dr), can be sensitive to D(sub max) assumptions. In past C-band radar studies, a variety of D(sub max) assumptions have been made, including the actual disdrometer estimate of D(sub max) during a typical sampling period (e.g., 1-3 minutes), D(sub max) = C (where C is constant at values from 5 to 8 mm), and D(sub max) = M*D0 (where the constant multiple, M, is fixed at values ranging from 2.5 to 3.5). The overall objective of this NASA Global Precipitation Measurement Mission (GPM/PMM Science Team)-funded study is to document the sensitivity of DSD measurements, including estimates of D0, from C-band Z(sub dr) and reflectivity to this range of D(sub max) assumptions. For this study, GPM Ground Validation 2DVD's were operated under the scanning domain of the UAHuntsville ARMOR C-band dual-polarimetric radar. Approximately 7500 minutes of DSD data were collected and processed to create gamma size distribution parameters using a truncated method of moments approach. After creating the gamma parameter datasets the DSD's were then used as input to a T-matrix model for computation of polarimetric radar moments at C-band. All necessary model parameterizations, such as temperature, drop shape, and drop fall mode, were fixed at typically accepted values while the D(sub max) assumption was allowed to vary in sensitivity tests. By hypothesizing a DSD model with D(sub max) (fit) from which the empirical fit to D0 = F[Z(sub dr)] was derived via non-linear least squares regression and a separate reference DSD model with D(sub max) (truth), bias and standard error in D0 retrievals were estimated in the presence of Z(sub dr) measurement error and hypothesized mismatch in D(sub max) assumptions. Although the normalized standard error for D0 = F[Z(sub dr)r] can increase slightly (as much as from 11% to 16% for all 7500 DSDs) when the D(sub max) (fit) does not match D(sub max) (truth), the primary impact of uncertainty in D(sub max) is a potential increase in normalized bias error in D0 (from 0% to as much as 10% over all 7500 DSDs, depending on the extent of the mismatch between D(sub max) (fit) and D(sub max) (truth)). For DSDs characterized by large Z(sub dr) (Z(sub dr) > 1.5 to 2.0 dB), the normalized bias error for D0 estimation at C-band is sometimes unacceptably large (> 10%), again depending on the extent of the hypothesized D(sub max) mismatch. Modeled errors in D0 retrievals from Z(sub dr) at C-band are demonstrated in detail and comparedo similar modeled retrieval errors at S-band and X-band where the sensitivity to D(sub max) is expected to be less. The impact of D(sub max) assumptions to the retrieval of other DSD parameters such as Nw, the liquid water content normalized intercept parameter, are also explored. Likely implications for DSD retrievals using C-band polarimetric radar for GPM are assessed by considering current community knowledge regarding D(sub max) and quantifying the statistical distribution of Z(sub dr) from ARMOR over a large variety of meteorological conditions. Based on these results and the prevalence of C-band polarimetric radars worldwide, a call for more emphasis on constraining our observational estimate of D(sub max) within a typical radar resolution volume is made

VO2 responses to intermittent swimming sets at velocity associated with VO2max.

PubMed

Libicz, Sebastien; Roels, Belle; Millet, Gregoire P

2005-10-01

While the physiological adaptations following endurance training are relatively well understood, in swimming there is a dearth of knowledge regarding the metabolic responses to interval training (IT). The hypothesis tested predicted that two different endurance swimming IT sets would induce differences in the total time the subjects swam at a high percentage of maximal oxygen consumption (VO(2)max). Ten trained triathletes underwent an incremental test to exhaustion in swimming so that the swimming velocity associated with VO(2)max (vVO(2)max) could be determined. This was followed by a maximal 400-m test and two intermittent sets at vVO(2)max: (a) 16 x 50 m with 15-s rest (IT(50)); (b) 8 x 100 m with 30-s rest (IT(100)). The times sustained above 95% VO(2)max (68.50 +/- 62.69 vs. 145.01 +/- 165.91 sec) and 95% HRmax (146.67 +/- 131.99 vs. 169.78 +/- 203.45 sec, p = 0.54) did not differ between IT(50) and IT(100)(values are mean +/- SD). In conclusion, swimming IT sets of equal time duration at vVO(2)max but of differing work-interval durations led to slightly different VO(2)and HR responses. The time spent above 95% of VO(2)max was twice as long in IT(100) as in IT (50), and a large variability between mean VO(2)and HR values was also observed.

Does maximum torque mean optimal pullout strength of screws?

PubMed

Tankard, Sara E; Mears, Simon C; Marsland, Daniel; Langdale, Evan R; Belkoff, Stephen M

2013-04-01

To determine the relationship between insertion torque and pullout strength of 3.5-mm-diameter cortical screws in cadaveric humeri with different bone mineral densities (BMDs). Five pairs of human humeri from each of 3 BMD groups (normal, osteopenic, and osteoporotic) were used. Holes were drilled in each humerus, and maximum insertion torque (T(max)) was measured by tightening a screw until stripping occurred. In the remaining holes, screws were tightened to 50%, 70%, or 90% of the T(max). A servohydraulic testing machine pulled each screw out at 1 mm/s while resulting force and axial displacement were recorded at 10 Hz. The authors checked for an effect of insertion torque (percent T(max)) on pullout strength using a general linearized and latent mixed model (Stata10), controlling for cortical thickness and BMD (T-score). Pullout strength for normal and osteoporotic bone was greatest for screws inserted to 50% T(max) and was significantly greater than that at T(max) but not significantly different from that at 70% or 90% T(max). For osteopenic bone, pullout strength was greatest at 70% peak torque, but it was not significantly different from the pullout strength at the 50% or 90% T(max) levels. Tightening screws beyond 50% T(max) does not increase pullout strength of the screw and may place bone at risk for damage that might result in loss of fixation. Even after adjusting for bone thickness and density, there is no clear relationship between pullout strength and screw torque.

Prediction of postoperative outcome after hepatectomy with a new bedside test for maximal liver function capacity.

PubMed

Stockmann, Martin; Lock, Johan F; Riecke, Björn; Heyne, Karsten; Martus, Peter; Fricke, Michael; Lehmann, Sina; Niehues, Stefan M; Schwabe, Michael; Lemke, Arne-Jörn; Neuhaus, Peter

2009-07-01

To validate the LiMAx test, a new bedside test for the determination of maximal liver function capacity based on C-methacetin kinetics. To investigate the diagnostic performance of different liver function tests and scores including the LiMAx test for the prediction of postoperative outcome after hepatectomy. Liver failure is a major cause of mortality after hepatectomy. Preoperative prediction of residual liver function has been limited so far. Sixty-four patients undergoing hepatectomy were analyzed in a prospective observational study. Volumetric analysis of the liver was carried out using preoperative computed tomography and intraoperative measurements. Perioperative factors associated with morbidity and mortality were analyzed. Cutoff values of the LiMAx test were evaluated by receiver operating characteristic. Residual LiMAx demonstrated an excellent linear correlation with residual liver volume (r = 0.94, P < 0.001) after hepatectomy. The multivariate analysis revealed LiMAx on postoperative day 1 as the only predictor of liver failure (P = 0.003) and mortality (P = 0.004). AUROC for the prediction of liver failure and liver failure related death by the LiMAx test was both 0.99. Preoperative volume/function analysis combining CT volumetry and LiMAx allowed an accurate calculation of the remnant liver function capacity prior to surgery (r = 0.85, P < 0.001). Residual liver function is the major factor influencing the outcome of patients after hepatectomy and can be predicted preoperatively by a combination of LiMAx and CT volumetry.

The Spatial Relationship between Apparent Diffusion Coefficient and Standardized Uptake Value of 18F-Fluorodeoxyglucose Has a Crucial Influence on the Numeric Correlation of Both Parameters in PET/MRI of Lung Tumors.

PubMed

Sauter, Alexander W; Stieltjes, Bram; Weikert, Thomas; Gatidis, Sergios; Wiese, Mark; Klarhöfer, Markus; Wild, Damian; Lardinois, Didier; Bremerich, Jens; Sommer, Gregor

2017-01-01

The minimum apparent diffusion coefficient (ADC min ) derived from diffusion-weighted MRI (DW-MRI) and the maximum standardized uptake value (SUV max ) of FDG-PET are markers of aggressiveness in lung cancer. The numeric correlation of the two parameters has been extensively studied, but their spatial interplay is not well understood. After FDG-PET and DW-MRI coregistration, values and location of ADC min - and SUV max -voxels were analyzed. The upper limit of the 95% confidence interval for registration accuracy of sequential PET/MRI was 12 mm, and the mean distance ( D ) between ADC min - and SUV max -voxels was 14.0 mm (average of two readers). Spatial mismatch ( D > 12 mm) between ADC min and SUV max was found in 9/25 patients. A considerable number of mismatch cases (65%) was also seen in a control group that underwent simultaneous PET/MRI. In the entire patient cohort, no statistically significant correlation between SUV max and ADC min was seen, while a moderate negative linear relationship ( r = -0.5) between SUV max and ADC min was observed in tumors with a spatial match ( D ≤ 12 mm). In conclusion, spatial mismatch between ADC min and SUV max is found in a considerable percentage of patients. The spatial connection of the two parameters SUV max and ADC min has a crucial influence on their numeric correlation.

Intertextuality and Television Discourse: The Max Headroom Story.

ERIC Educational Resources Information Center

Braddlee

Max Headroom, the computer-generated media personality, presents a good opportunity for an investigation of the degree of intertextuality in television. Max combines narrative genres (science fiction and film noir), television program types (prime-time episodic narrative, made-for-TV movie, talkshows), advertising and programming, and electronic…

Effect of Toe Clips During Bicycle Ergometry on VO2 max.

ERIC Educational Resources Information Center

Moffat, Roger S.; Sparling, Phillip B.

1985-01-01

Eight men participated in three randomized maximal oxygen uptake tests to investigate the hypothesis that the use of toe clips on bicycle ergometers produced a higher VO2 max. No significant difference in mean VO2 max or performance time was observed. (Author/MT)

Photosynthesis, Earth System Models and the Arctic

NASA Astrophysics Data System (ADS)

Rogers, A.; Sloan, V. L.; Xu, C.; Wullschleger, S. D.

2013-12-01

The primary goal of Earth System Models (ESMs) is to improve understanding and projection of future global change. In order to do this they must accurately represent the huge carbon fluxes associated with the terrestrial carbon cycle. Photosynthetic CO2 uptake is the largest of these fluxes, and is well described by the Farquhar, von Caemmerer and Berry (FvCB) model of photosynthesis. Most ESMs use a derivation of the FvCB model to calculate gross primary productivity (GPP). One of the key parameters required by the FvCB model is an estimate of the maximum rate of carboxylation by the enzyme Rubisco (Vc,max). In ESMs the parameter Vc,max is usually fixed for a given plant functional type (PFT). Although Arctic GPP a small flux relative to global GPP, uncertainty is large. Only four ESMs currently have an explicit Arctic PFT and the data used to derive Vc,max for the Arctic PFT in these models relies on small data sets and unjustified assumptions. As part of a multidisciplinary project to improve the representation of the Arctic in ESMs (Next Generation Ecosystem Experiments - Arctic) we examined the derivation of Vc,max in current Arctic PFTs and estimated Vc,max for 12 species representing both dominant vegetation and key PFTs growing on the Barrow Environmental Observatory, Barrow, AK. The values of Vc,max currently used to represent Arctic PFTs in ESMs are 70% lower than the values we measured in these species. Separate measurements of CO2 assimilation (A) made at ambient conditions were compared with A modeled using the Vc,max values we measured in Barrow and those used by the ESMs. The A modeled with the Vc,max values used by the ESMs was 80% lower than the observed A. When our measured Vc,max values were used, modeled A was within 5% of observed A. Examination of the derivation of Vc,max in ESMs identified that the cause of the relatively low Vc,max value was the result of underestimating both the leaf N content and the investment of that N in Rubisco. Here we have identified possible improvements to the derivation of Vc,max in ESMs and provided new physiological characterization of Arctic species that is mechanistically consistent with observed leaf level CO2 uptake. These data suggest that the Arctic tundra has a much greater capacity for CO2 uptake than is currently represented in ESMs. Our parameterization can be used in future model projections to improve representation of the Arctic landscape in ESMs.

TU-FG-201-09: Predicting Accelerator Dysfunction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Able, C; Nguyen, C; Baydush, A

Purpose: To develop an integrated statistical process control (SPC) framework using digital performance and component data accumulated within the accelerator system that can detect dysfunction prior to unscheduled downtime. Methods: Seven digital accelerators were monitored for twelve to 18 months. The accelerators were operated in a ‘run to failure mode’ with the individual institutions determining when service would be initiated. Institutions were required to submit detailed service reports. Trajectory and text log files resulting from a robust daily VMAT QA delivery were decoded and evaluated using Individual and Moving Range (I/MR) control charts. The SPC evaluation was presented in amore » customized dashboard interface that allows the user to review 525 monitored parameters (480 MLC parameters). Chart limits were calculated using a hybrid technique that includes the standard SPC 3σ limits and an empirical factor based on the parameter/system specification. The individual (I) grand mean values and control limit ranges of the I/MR charts of all accelerators were compared using statistical (ranked analysis of variance (ANOVA)) and graphical analyses to determine consistency of operating parameters. Results: When an alarm or warning was directly connected to field service, process control charts predicted dysfunction consistently on beam generation related parameters (BGP)– RF Driver Voltage, Gun Grid Voltage, and Forward Power (W); beam uniformity parameters – angle and position steering coil currents; and Gantry position accuracy parameter: cross correlation max-value. Control charts for individual MLC – cross correlation max-value/position detected 50% to 60% of MLCs serviced prior to dysfunction or failure. In general, non-random changes were detected 5 to 80 days prior to a service intervention. The ANOVA comparison of BGP determined that each accelerator parameter operated at a distinct value. Conclusion: The SPC framework shows promise. Long term monitoring coordinated with service will be required to definitively determine the effectiveness of the model. Varian Medical System, Inc. provided funding in support of the research presented.« less

Thoracic aorta 3D hemodynamics in pediatric and young adult patients with bicuspid aortic valve.

PubMed

Allen, Bradley D; van Ooij, Pim; Barker, Alex J; Carr, Maria; Gabbour, Maya; Schnell, Susanne; Jarvis, Kelly B; Carr, James C; Markl, Michael; Rigsby, Cynthia; Robinson, Joshua D

2015-10-01

To evaluate the 3D hemodynamics in the thoracic aorta of pediatric and young adult bicuspid aortic valve (BAV) patients. 4D flow MRI was performed in 30 pediatric and young adult BAV patients (age: 13.9 ± 4.4 (range: [3.4, 20.7]) years old, M:F = 17:13) as part of this Institutional Review Board-approved study. Nomogram-based aortic root Z-scores were calculated to assess aortic dilatation and degree of aortic stenosis (AS) severity was assessed on MRI. Data analysis included calculation of time-averaged systolic 3D wall shear stress (WSSsys ) along the entire aorta wall, and regional quantification of maximum and mean WSSsys and peak systolic velocity (velsys ) in the ascending aorta (AAo), arch, and descending aorta (DAo). The 4D flow MRI AAo velsys was also compared with echocardiography peak velocity measurements. There was a positive correlation with both mean and max AAo WSSsys and peak AAo velsys (mean: r = 0.84, P < 0.001, max: r = 0.94, P < 0.001) and AS (mean: rS  = 0.43, P = 0.02, max: rS  = 0.70, P < 0.001). AAo peak velocity was significantly higher when measured with echo compared with 4D flow MRI (2.1 ± 0.98 m/s versus 1.27 ± 0.49 m/s, P < 0.001). In pediatric and young adult patients with BAV, AS and peak ascending aorta velocity are associated with increased AAo WSS, while aortic dilation, age, and body surface area do not significantly impact AAo hemodynamics. Prospective studies are required to establish the role of WSS as a risk-stratification tool in these patients. © 2015 Wiley Periodicals, Inc.

76 FR 36081 - Hot-Rolled Flat-Rolled Carbon-Quality Steel Products From Brazil and Japan: Revocation of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-21

... the following chemical, physical and mechanical specifications: C Mn P S Si Cr Cu Ni 0.10-0.14% 0.90... P S Si Cr Cu Ni 0.10-0.16% 0.70-0.90% 0.025% Max 0.006% Max 0.30-0.50% 0.50-0.70% 0.25% Max 0.20... chemical, physical and mechanical specifications: C Mn P S Si Cr Cu Ni 0.10-0.14% 1.30-1.80% 0.025% Max 0...

Evaluation of Maximal Oxygen Uptake and Submaximal Estimates of VO2max Before, During, and After Long Duration International Space Station Missions

NASA Technical Reports Server (NTRS)

2008-01-01

Evaluation of Maximal Oxygen Uptake and Submaximal Estimates of VO2max Before, During, and After Long Duration International Space Station Missions (VO2max) will document changes in maximum oxygen uptake for crewmembers onboard the International Space Station (ISS) on long-duration missions, greater than 90 days. This investigation will establish the characteristics of VO2max during flight and assess the validity of the current methods of tracking aerobic capacity change during and following the ISS missions.

ELA-max: A new topical lidocaine formulation.

PubMed

Goldman, Ran D

2004-05-01

To evaluate the role of a new formulation of lidocaine (ELA-max) in local anesthesia in children and compare it with the eutectic mixture of local anesthetics (EMLA). Relevant literature was identified by a MEDLINE search (1966-November 2003) using the search terms ELA-max and EMLA. Bibliographies of selected articles were also examined to include all relevant investigations. The product manufacturer was contacted for inclusion of the most recent data available. Topical anesthesia in children is clinically challenging. ELA-max has been shown to be as effective as EMLA for venipuncture in children, but with faster onset. Adverse effects, such as transient blanching with redness and erythema, have been reported. Further investigation is needed to determine the effectiveness of ELA-max on other painful procedures in children, as well as its safety.

Strigolactones, karrikins and beyond.

PubMed

De Cuyper, Carolien; Struk, Sylwia; Braem, Lukas; Gevaert, Kris; De Jaeger, Geert; Goormachtig, Sofie

2017-09-01

The plant hormones strigolactones are synthesized from carotenoids and signal via the α/β hydrolase DWARF 14 (D14) and the F-box protein MORE AXILLARY GROWTH 2 (MAX2). Karrikins, molecules produced upon fire, share MAX2 for signalling, but depend on the D14 paralog KARRIKIN INSENSITIVE 2 (KAI2) for perception with strong evidence that the MAX2-KAI2 protein complex might also recognize so far unknown plant-made karrikin-like molecules. Thus, the phenotypes of the max2 mutants are the complex consequence of a loss of both D14-dependent and KAI2-dependent signalling, hence, the reason why some biological roles, attributed to strigolactones based on max2 phenotypes, could never be observed in d14 or in the strigolactone-deficient max3 and max4 mutants. Moreover, the broadly used synthetic strigolactone analog rac-GR24 has been shown to mimic strigolactone as well as karrikin(-like) signals, providing an extra level of complexity in the distinction of the unique and common roles of both molecules in plant biology. Here, a critical overview is provided of the diverse biological processes regulated by strigolactones and/or karrikins. These two growth regulators are considered beyond their boundaries, and the importance of the yet unknown karrikin-like molecules is discussed as well. © 2017 John Wiley & Sons Ltd.

GreedyMAX-type Algorithms for the Maximum Independent Set Problem

NASA Astrophysics Data System (ADS)

Borowiecki, Piotr; Göring, Frank

A maximum independent set problem for a simple graph G = (V,E) is to find the largest subset of pairwise nonadjacent vertices. The problem is known to be NP-hard and it is also hard to approximate. Within this article we introduce a non-negative integer valued function p defined on the vertex set V(G) and called a potential function of a graph G, while P(G) = max v ∈ V(G) p(v) is called a potential of G. For any graph P(G) ≤ Δ(G), where Δ(G) is the maximum degree of G. Moreover, Δ(G) - P(G) may be arbitrarily large. A potential of a vertex lets us get a closer insight into the properties of its neighborhood which leads to the definition of the family of GreedyMAX-type algorithms having the classical GreedyMAX algorithm as their origin. We establish a lower bound 1/(P + 1) for the performance ratio of GreedyMAX-type algorithms which favorably compares with the bound 1/(Δ + 1) known to hold for GreedyMAX. The cardinality of an independent set generated by any GreedyMAX-type algorithm is at least sum_{vin V(G)} (p(v)+1)^{-1}, which strengthens the bounds of Turán and Caro-Wei stated in terms of vertex degrees.

The oral iron chelator deferasirox might improve survival in allogeneic hematopoietic cell transplant (alloHSCT) recipients with transfusional iron overload.

PubMed

Sivgin, Serdar; Baldane, Suleyman; Akyol, Gulsah; Keklik, Muzaffer; Kaynar, Leylagül; Kurnaz, Fatih; Pala, Cigdem; Zararsiz, Gokmen; Cetin, Mustafa; Eser, Bulent; Unal, Ali

2013-10-01

Iron overload (IO) has been shown to be an important cause of mortality and morbidity in patients who underwent allogeneic hematopoietic stem cell transplantation (alloHSCT). This study aimed to evaluate the possible effect of oral iron-chelation treatment (deferasirox) on survival in alloHSCT recipients in the posttransplant period. A total of 80 alloHSCT recipients with IO were analyzed, retrospectively. Pretransplant and posttransplant data were obtained from the patients' files. Patients were divided into two groups. Group 1; patients who did not receive any chelator treatment due to side effects or compliance problems. These patients were treated by phlebotomy. Group 2 consisted of patients who received deferasirox treatment. The median treatment duration with deferasirox was 122 days (min-max:91-225). The iron chelating treatment significantly reduced serum ferritin levels administered at a dosage of 20-30 mg/kg/day (p<0.001). The median OS in Group 1 was found 16.0 (min-max:1.0-63.0) months and 25.0 (min-max:3.0-72.0) months in Group 2. In univariate and multivariate analysis, patients in Group 1 showed poorer OS compared to those in Group 2 with an increase in risk of death (HR:3.22, min-max:1.67-6.23, p=0.001 and HR:3.51,, min-max:1.75-6.99, p<0.001; respectively). The median DFS in Group 1 was found 11.0 (min-max:3.0-24.0) months and 22.0 (min-max:8.0-43.0) months in Group 2. The difference was found statistically significant (p=0.023). The other factors that we found significant difference in multivariate analysis between groups were; presence of acute GVHD (patients with aGVHD had increased risk of death compared to patients without aGVHD (HR:2.49, min-max: 1.32-4.69, p=0.005), chronic GVHD (HR:2.57, min-max:1.23-5.41, p=0.013), median interval to tx (HR: 2.23, min-max:1.17-4.26, p=0.015) and HLA match (HR:3.01, min-max:1.35-6.73, p=0.007) CONCLUSION: Oral deferasirox (Exjade) treatment may improve survival in patients with iron overload who underwent alloHSCT. Copyright © 2013 Elsevier Ltd. All rights reserved.

Improving the representation of Arctic photosynthesis in Earth system models

NASA Astrophysics Data System (ADS)

Rogers, A.; Serbin, S.; Ely, K.; Sloan, V. L.; Wyatt, R. A.; Kubien, D. S.; Ali, A. A.; Xu, C.; Wullschleger, S. D.

2015-12-01

The primary goal of Earth System Models (ESMs) is to improve understanding and projection of future global change. In order to do this they must accurately represent the carbon fluxes associated with the terrestrial carbon cycle. Although Arctic carbon fluxes are small - relative to global carbon fluxes - uncertainty is large. As part of a multidisciplinary project to improve the representation of the Arctic in ESMs (Next Generation Ecosystem Experiments - Arctic) we are examining the photosynthetic parameterization of the Arctic plant functional type (PFT) in ESMs. Photosynthetic CO2 uptake is well described by the Farquhar, von Caemmerer and Berry (FvCB) model of photosynthesis. Most ESMs use a derivation of the FvCB model to calculate gross primary productivity. Two key parameters required by the FvCB model are an estimate of the maximum rate of carboxylation by the enzyme Rubisco (Vc,max) and the maximum rate of electron transport (Jmax). In ESMs the parameter Vc,max is usually fixed for a given PFT. Only four ESMs currently have an explicit Arctic PFT and the data used to derive Vc,max for the Arctic PFT in these models relies on small data sets and unjustified assumptions. We examined the derivation of Vc,max and Jmax in current Arctic PFTs and estimated Vc,max and Jmax for 7 species representing both dominant vegetation and key Arctic PFTs growing on the Barrow Environmental Observatory, Barrow, AK. The values of Vc,max currently used to represent Arctic PFTs in ESMs are 70% lower than the values we measured in these species. Examination of the derivation of Vc,max in ESMs identified that the cause of the relatively low Vc,max value was the result of underestimating both the leaf N content and the investment of that N in Rubisco. Contemporary temperature response functions for Vc,max also appear to underestimate Vc,max at low temperature. ESMs typically use a single multiplier (JVratio) to convert Vc,max to Jmax for all PFTs. We found that the JVratio of Arctic plants is higher than current estimates suggesting that the Arctic PFT will be more responsive to rising carbon dioxide than currently projected. Our data suggest that the Arctic tundra has a much greater capacity for CO2 uptake, particularly at low temperature, and will be more CO2 responsive than is currently represented in ESMs.

X-ray study of mesomorphism of bent-core and chromonic mesogens

NASA Astrophysics Data System (ADS)

Joshi, Leela Pradhan

The discovery of thermotropic biaxial nematic phase in bent-core mesogens, have engendered interest in these systems. Also, it undergoes optical switching about 100 times faster than conventional uniaxial nematic liquid crystal. Azo-substituted bent-core compounds, A131 and A103, were investigated as both offer an opportunity to observe their structures and phase transitions from the uniaxial nematic (Nu) to biaxial nematic (Nb) phase and from Nb to the underlying smectic-C (SmC) phase. Plank-like molecular systems are also expected to form Nb phase. Chromonic liquid crystals formed by aqueous solutions of plank-like dye molecules are interesting for their unique self-assembly and structural evolution. They have applications in optical element, coloring in food and textiles, and etc. Both systems were investigated with synchrotron x-ray scattering, polarizing optical microscopy, and differential scanning calorimetry. Temperature dependence of d-spacing and positional order correlations along the director clearly mark the phase boundaries where Nu-Nb transition was approximately 27° below the clearing point. Positional order correlation length of A131 increased from 1.5 in Nu to 3.3 molecular lengths in Nb phase, before it jumps by a factor of at least 5 in SmC phase. The lack of large discontinuous changes in the structural parameters and the subtle signatures in heat capacity establish the second order nature of Nu-Nb and Nb-SmC phase transitions. The chromonic system investigation results provide quantitative information of structural properties in nematic and columnar mesophases. We studied water solutions of (achiral) sunset yellow dye and (chiral and achiral) dihydrochloride salts of perylenebis-dicarboxydiimide. Positional order correlation lengths measurements, parallel and perpendicular to the aggregate axis, revealed that they increase with concentration and decrease with temperature. Temperature dependence of correlation lengths yielded the scission energy to be 1.8 (+/-0.1) x10-20J and 1.5 (+/-0.08) x10-20J in the nematic and columnar phases. The aggregates' small aspect ratio (2.5) is inconsistent with the Onsager model for the formation of an orientationally ordered phase, which strongly suggests more complicated aggregate-shape than simple cylindrical objects as postulated by Laventovich, et al.