maximum observed plasma: Topics by Science.gov

Observations of Halley's Comet by the Solar Maximum Mission (SMM)

NASA Technical Reports Server (NTRS)

Niedner, M. B.

1986-01-01

Solar Maximum Mission coronagraph/polarimeter observations of large scale phenomena in Halley's Comet are discussed. Observations of the hydrogen coma with the UV spectrometer are considered. It is concluded that coronograph/polarimeter observations of the disconnection event, in which the entire plasma tail uproots itself from the head of the comet, is convected away in the solar wind at speeds in the 50 to 100 km/sec range (relative to the head), and is replaced by a plasma tail constructed from folding ion-tail rays, are the most interesting.
Note: Characterization of the plasma parameters of a capillary discharge-produced plasma channel waveguide to guide an intense laser pulse

DOE Office of Scientific and Technical Information (OSTI.GOV)

Higashiguchi, Takeshi; Yugami, Noboru; CREST, Japan Science and Technology Agency, 4-1-8 Honcho, Kanagawa, Saitama 332-0012

2010-04-15

We demonstrated the production of an optical waveguide in a capillary discharge-produced plasma using a cylindrical capillary. Plasma parameters of its waveguide were characterized by use of both a Nomarski laser interferometer and a hydrogen plasma line spectrum. A space-averaged maximum temperature of 3.3 eV with electron densities of the order of 10{sup 17} cm{sup -3} was observed at a discharge time of 150 ns and a maximum discharge current of 400 A. An ultrashort, intense laser pulse was guided by use of this plasma channel.
T he Analysis of the seasonal variations of equatorial plasma bubble, occurrence observed from Oukaimeden Observatory, Morroco

NASA Astrophysics Data System (ADS)

Amine, Lagheryeb; Zouhair, Benkhaldoun; Jonathan, Makela; Mohamed, Kaab; Aziza, Bounhir; Brian, Hardin; Dan, Fisher; Tmuthy, Duly

2016-04-01

T he Analysis of the seasonal variations of equatorial plasma bubble, occurrence using the 630.0 nm airglow images collected by the PICASSO imager deployed at the Oukkaimden observatory in Morocco. Data have been taken since November 2013 to december 2015. We show the monthly average of appearance of EPBs. A maximum probability for bubble development is seen in the data in January and between late February and early March. We also observe that there are a maximum period of appearance where the plasma is observed (3-5 nights successivies) and we will discuss its connection with the solar activity in storm time. Future analysis will compare the probability of bubble occurrence in our site with the data raised in other observation sites.
Carbon dioxide dissociation in non-thermal radiofrequency and microwave plasma

NASA Astrophysics Data System (ADS)

Huang, Qiang; Zhang, Diyu; Wang, Dongping; Liu, Kezhao; Kleyn, Aart W.

2017-07-01

We have studied carbon dioxide dissociation in inductively coupled radiofrequency plasma and microwave plasma at low gas pressure. Both systems exhibit features of non-thermal plasma. The highest energy efficiency observed is 59.3% (2.13 mmol kJ-1), exceeding the maximum value of about 45% in case of thermodynamic equilibrium, and a maximum conversion of 80.6% is achieved. Different discharge conditions, such as the source frequency, discharge gas pressure and the addition of argon, will affect the plasma parameters, especially the electron energy distribution. This plays a great role in the energy transfer from non-thermal plasma to the molecular dissociation reaction channel by enabling the ladder climbing of the carbon dioxide molecular vibration. The results indicate the importance of ladder climbing.
Vertical rise velocity of equatorial plasma bubbles estimated from Equatorial Atmosphere Radar (EAR) observations and HIRB model simulations

NASA Astrophysics Data System (ADS)

Tulasi Ram, S.; Ajith, K. K.; Yokoyama, T.; Yamamoto, M.; Niranjan, K.

2017-06-01

The vertical rise velocity (Vr) and maximum altitude (Hm) of equatorial plasma bubbles (EPBs) were estimated using the two-dimensional fan sector maps of 47 MHz Equatorial Atmosphere Radar (EAR), Kototabang, during May 2010 to April 2013. A total of 86 EPBs were observed out of which 68 were postsunset EPBs and remaining 18 EPBs were observed around midnight hours. The vertical rise velocities of the EPBs observed around the midnight hours are significantly smaller ( 26-128 m/s) compared to those observed in postsunset hours ( 45-265 m/s). Further, the vertical growth of the EPBs around midnight hours ceases at relatively lower altitudes, whereas the majority of EPBs at postsunset hours found to have grown beyond the maximum detectable altitude of the EAR. The three-dimensional numerical high-resolution bubble (HIRB) model with varying background conditions are employed to investigate the possible factors that control the vertical rise velocity and maximum attainable altitudes of EPBs. The estimated rise velocities from EAR observations at both postsunset and midnight hours are, in general, consistent with the nonlinear evolution of EPBs from the HIRB model. The smaller vertical rise velocities (Vr) and lower maximum altitudes (Hm) of EPBs during midnight hours are discussed in terms of weak polarization electric fields within the bubble due to weaker background electric fields and reduced background ion density levels.Plain Language SummaryEquatorial plasma bubbles are plasma density irregularities in the ionosphere. The radio waves passing through these irregular density structures undergo severe degradation/scintillation that could cause severe disruption of satellite-based communication and augmentation systems such as GPS navigation. These bubbles develop at geomagnetic equator, grow vertically, and elongate along the field lines to latitudes away from the equator. The knowledge on bubble rise velocities and their maximum attainable altitudes improves the accuracy of scintillation forecasting at latitudes away from the equator and helps in mitigating the errors in satellite-based augmentation systems. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19930019969','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19930019969">Preliminary investigation of high power microwave plasmas for electrothermal thruster use</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Power, John L.; Sullivan, Daniel J. 1993-01-01 Results are reported from preliminary tests to evaluate the high power microwave electrothermal thruster (MET) concept, which employs a free-floating plasma discharge maintained by applied CW microwave power to heat a propellant gas flow. Stable plasmas have been created and maintained in helium (He), nitrogen (N2), and hydrogen (H2) as propellants in both the TM(sub 011) and TM(sub 012) modes at discharge pressures from 10 Pa to 69 kPa. Reproducible starting conditions of pressure and power have been documented for all the plasmas. Vortical inflow of the propellant gas was observed to cause the formation of on-axis 'spike' plasmas. The formation and unformation conditions of these plasmas were studied. Operation in the spike plasma condition enables maximum power absorption with minimum wall heating and offers maximum efficiency in heating the propellant gas. In the spike condition, plasmas of the three propellant gases were investigated in an open channel configuration to a maximum applied power level of 11.2 kW (in N2). Microwave power coupling efficiencies of over 90 percent were routinely obtained at absorbed power levels up to 2 kW. Magnetic nozzle effects were investigated with a superconducting solenoid Al magnet applying a high magnetic field to the plasmas in and exiting from the discharge tube. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013JIEIE..94....1P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013JIEIE..94....1P">Desizing of Starch Containing Cotton Fabrics Using Near Atmospheric Pressure, Cold DC Plasma Treatment</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Prasath, A.; Sivaram, S. S.; Vijay Anand, V. D.; Dhandapani, Saravanan 2013-03-01 An attempt has been made to desize the starch containing grey cotton fabrics using the DC plasma with oxygen as the gaseous medium. Process conditions of the plasma reactor were optimized in terms of distance between the plates (3.2 cm), applied voltage (600 V) and applied pressure (0.01 bar) to obtain maximum desizing efficiency. No discolouration was observed in the hot water extracts of the desized sample in presence of iodine though relatively higher solvent extractable impurities (4.53 %) were observed in the plasma desized samples compared to acid desized samples (3.38 %). Also, significant weight loss, improvements in plasma desized samples were observed than that of grey fabrics in terms of drop absorbency. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19910030156&hterms=Increased+entropy&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D60%26Ntt%3DIncreased%2Bentropy','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19910030156&hterms=Increased+entropy&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D60%26Ntt%3DIncreased%2Bentropy">Shock heating of the solar wind plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Whang, Y. C.; Liu, Shaoliang; Burlaga, L. F. 1990-01-01 The role played by shocks in heating solar-wind plasma is investigated using data on 413 shocks which were identified from the plasma and magnetic-field data collected between 1973 and 1982 by Pioneer and Voyager spacecraft. It is found that the average shock strength increased with the heliocentric distance outside 1 AU, reaching a maximum near 5 AU, after which the shock strength decreased with the distance; the entropy of the solar wind protons also reached a maximum at 5 AU. An MHD simulation model in which shock heating is the only heating mechanism available was used to calculate the entropy changes for the November 1977 event. The calculated entropy agreed well with the value calculated from observational data, suggesting that shocks are chiefly responsible for heating solar wind plasma between 1 and 15 AU. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20170002781&hterms=location&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dlocation','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20170002781&hterms=location&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dlocation">Comparison of Magnetospheric Multiscale Ion Jet Signatures with Predicted Reconnection Site Locations at the Magnetopause</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Petrinec, S. M.; Burch, J. L.; Fuselier, S. A.; Gomez, R. G.; Lewis, W.; Trattner, K. J.; Ergun, R.; Mauk, B.; Pollock, C. J.; Schiff, C.; <a style="text-decoration: none; " href="javascript:void(0); " onClick="displayelement('author_20170002781'); toggleEditAbsImage('author_20170002781_show'); toggleEditAbsImage('author_20170002781_hide'); "> <img style="display:inline; width:12px; height:12px; " src="images/arrow-up.gif" width="12" height="12" border="0" alt="hide" id="author_20170002781_show"> <img style="width:12px; height:12px; display:none; " src="images/arrow-down.gif" width="12" height="12" border="0" alt="hide" id="author_20170002781_hide"> 2016-01-01 Magnetic reconnection at the Earths magnetopause is the primary process by which solar wind plasma and energy gains access to the magnetosphere. One indication that magnetic reconnection is occurring is the observation of accelerated plasma as a jet tangential to the magnetopause. The direction of ion jets along the magnetopause surface as observed by the Fast Plasma Instrument (FPI) and the Hot Plasma Composition Analyzer (HPCA) instrument on board the recently launched Magnetospheric Multiscale (MMS) set of spacecraft is examined. For those cases where ion jets are clearly discerned, the direction of origin compares well statistically with the predicted location of magnetic reconnection using convected solar wind observations in conjunction with the Maximum Magnetic Shear model. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19970005010','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19970005010">Maximum Langmuir Fields in Planetary Foreshocks Determined from the Electrostatic Decay Threshold</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Robinson, P. A.; Cairns, Iver H. 1995-01-01 Maximum electric fields of Langmuir waves at planetary foreshocks are estimated from the threshold for electrostatic decay, assuming it saturates beam driven growth, and incorporating heliospheric variation of plasma density and temperature. Comparisons with spacecraft observations yields good quantitative agreement. Observations in type 3 radio sources are also in accord with this interpretation. A single mechanism can thus account for the highest fields of beam driven waves in both contexts. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3579268','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3579268">Effects of atomoxetine on the QT interval in healthy CYP2D6 poor metabolizers</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Loghin, Corina; Haber, Harry; Beasley, Charles M; Kothare, Prajakti A; Kauffman, Lynnette; April, John; Jin, Ling; Allen, Albert J; Mitchell, Malcolm I 2013-01-01 Aim The effects of atomoxetine (20 and 60 mg twice daily), 400 mg moxifloxacin and placebo on QTc in 131 healthy CYP2D6 poor metabolizer males were compared. Methods Atomoxetine doses were selected to result in plasma concentrations that approximated expected plasma concentrations at both the maximum recommended dose and at a supratherapeutic dose in CYP2D6 extensive metabolizers. Ten second electrocardiograms were obtained for time-matched baseline on days −2 and −1, three time points after dosing on day 1 for moxifloxacin and five time points on day 7 for atomoxetine and placebo. Maximum mean placebo-subtracted change from baseline model-corrected QT (QTcM) on day 7 was the primary endpoint. Results QTcM differences for atomoxetine 20 and 60 mg twice daily were 0.5 ms (upper bound of the one-sided 95% confidence interval 2.2 ms) and 4.2 ms (upper bound of the one-sided 95% confidence interval 6.0 ms), respectively. As plasma concentration of atomoxetine increased, a statistically significant increase in QTc was observed. The moxifloxacin difference from placebo met the a priori definition of non-inferiority. Maximum mean placebo-subtracted change from baseline QTcM for moxifloxacin was 4.8 ms and this difference was statistically significant. Moxifloxacin plasma concentrations were below the concentrations expected from the literature. However, the slope of the plasma concentration−QTc change observed was consistent with the literature. Conclusion Atomoxetine was not associated with a clinically significant change in QTc. However, a statistically significant increase in QTc was associated with increasing plasma concentrations. PMID:22803597 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=163054','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=163054">Pharmacokinetics and penetration into inflammatory fluid of trovafloxacin (CP-99,219).</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Wise, R; Mortiboy, D; Child, J; Andrews, J M 1996-01-01 A single 200-mg oral dose of trovafloxacin (CP-99,219) was given to each of eight healthy male volunteers, and the concentrations of the drug were measured in plasma, cantharides-induced inflammatory fluid, and urine over the subsequent 36 h. The mean maximum concentration observed in plasma was 2.9 micrograms/ml at a mean time of 0.75 h postdose. The mean maximum concentration observed in inflammatory fluid was 1.2 micrograms/ml at 4.0 h postdose. The mean elimination half-life in plasma was 7.8 h. The overall penetration into inflammatory fluid was 64%, as assessed by determining the ratio of the area under the concentration-time curves. Recovery of the dose in urine within the first 36 h postdose was 5.0% of the administered dose. Our results indicate that trovafloxacin, at a dosage of 200 mg once or twice daily, should be adequate for the treatment of systemic infections caused by most common bacterial pathogens. PMID:8787877 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010PhPl...17h2506M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010PhPl...17h2506M">Equilibrium evolution in oscillating-field current-drive experiments</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> McCollam, K. J.; Anderson, J. K.; Blair, A. P.; Craig, D.; Den Hartog, D. J.; Ebrahimi, F.; O'Connell, R.; Reusch, J. A.; Sarff, J. S.; Stephens, H. D.; Stone, D. R.; Brower, D. L.; Deng, B. H.; Ding, W. X. 2010-08-01 Oscillating-field current drive (OFCD) is a proposed method of steady-state toroidal plasma sustainment in which ac poloidal and toroidal loop voltages are applied to produce a dc plasma current. OFCD is added to standard, inductively sustained reversed-field pinch plasmas in the Madison Symmetric Torus [R. N. Dexter et al., Fusion Technol. 19, 131 (1991)]. Equilibrium profiles and fluctuations during a single cycle are measured and analyzed for different relative phases between the two OFCD voltages and for OFCD off. For OFCD phases leading to the most added plasma current, the measured energy confinement is slightly better than that for OFCD off. By contrast, the phase of the maximum OFCD helicity-injection rate also has the maximum decay rate, which is ascribed to transport losses during discrete magnetic-fluctuation events induced by OFCD. Resistive-magnetohydrodynamic simulations of the experiments reproduce the observed phase dependence of the added current. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2006PlST....8...84H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2006PlST....8...84H">Preliminary Experiment of Non-Inductive Plasma Current Startup in SUNIST Spherical Tokamak</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> He, Yexi; Zhang, Liang; Xie, Lifeng; Tang, Yi; Yang, Xuanzong; Feng, Chunhua; Fu, Hongjun 2006-01-01 The non-inductive plasma current startup is an important motivation in SUNIST spherical tokamak. In the recent experiment, the magnetron microwave system of 100 kW and 2.45 GHz has been used to the ECR plasma current startup. Besides the toroidal field, a vertical field was applied to generate preliminary toroidal plasma current without the action of the central solenoid. As the evidence of plasma current startup with the effect of vertical field drift, the direction of plasma current is changed when the direction of vertical field changes during the ECR plasma current startup discharge. We also observed a maximum plasma current by scanning vertical field in both directions. Additionally, we used electrode discharge to assist the ECR plasma current startup. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009P%26SS...57.1779R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009P%26SS...57.1779R">Cassini evidence for rapid interchange transport at Saturn</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Rymer, A. M.; Mauk, B. H.; Hill, T. W.; André, N.; Mitchell, D. G.; Paranicas, C.; Young, D. T.; Smith, H. T.; Persoon, A. M.; Menietti, J. D.; Hospodarsky, G. B.; Coates, A. J.; Dougherty, M. K. 2009-12-01 During its tour Cassini has observed numerous plasma injection events in Saturn's inner magnetosphere. Here, we present a case study of one "young" plasma bubble observed when Cassini was in the equatorial plane. The bubble was observed in the equatorial plane at ˜7 Saturn radii from Saturn and had a maximum azimuthal extent of ˜0.25 Rs (Rs=Saturn radius ˜60330 km). We show that the electron density inside the event is lower by a factor ˜3 and the electron temperature higher by over an order of magnitude compared to its surroundings. The injection contains slightly increased magnetic field magnitude of 49 nT compared with a background field of 46 nT. Modelling of pitch angle distributions inside the plasma bubble and measurements of plasma drift provide a novel way to estimate that the bubble originated between 9< L<11 and had an average radial propagation speed of ˜260+60/-70 km s -1. An independent estimate of the speed of the injection following theoretical work of Pontius et al. [1986. Steady State Plasma transport in a Corotation-Dominated Magnetosphere. Geophys. Res. Lett. 13(11), 1097-1100] based on the mass per unit flux gives a maximum radial propagation speeds of 140 km s -1. These results are similar to those found by Thorne et al. [1997. Galileo evidence for rapid interchange transport in the Io torus. Geophys. Res. Lett. 24, 2131] for one event observed in Jupiter's magnetosphere near Io. We therefore suggest this is evidence of the same process operating at both planets. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1984MmSAI..55..673C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1984MmSAI..55..673C">Results from the X-ray polychromator on SMM</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Culhane, J. L.; Acton, L. W.; Gabriel, A. H. Observations of the soft X-ray emitting plasma by means of the X-Ray Polychromator (XRP) on the Solar Maximum Mission satellite are described. The scientific advances achieved by use of the XRP are in the areas of: (1) flare morphology, (2) spectroscopy and plasma diagnostics, (3) chromospheric evaporation and the physics of flare loops, (4) studies of the microwave emission mechanisms of active regions, (5) the fluorescent excitation of Fe II K-alpha radiation, (6) measurement of variations of calcium abundance for X-ray plasmas, and (7) soft X-ray observations of spray transients. The findings in each of these areas are discussed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19850061761&hterms=XRP&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3DXRP','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19850061761&hterms=XRP&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3DXRP">Results from the X-ray polychromator on SMM</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Culhane, J. L.; Acton, L. W.; Gabriel, A. H. 1984-01-01 Observations of the soft X-ray emitting plasma by means of the X-Ray Polychromator (XRP) on the Solar Maximum Mission satellite are described. The scientific advances achieved by use of the XRP are in the areas of: (1) flare morphology, (2) spectroscopy and plasma diagnostics, (3) chromospheric evaporation and the physics of flare loops, (4) studies of the microwave emission mechanisms of active regions, (5) the fluorescent excitation of Fe II K-alpha radiation, (6) measurement of variations of calcium abundance for X-ray plasmas, and (7) soft X-ray observations of spray transients. The findings in each of these areas are discussed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/488570','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/488570">The effect of unabsorbable carbohydrate on gut hormones. Modification of post-prandial GIP secretion by guar.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Morgan, L M; Goulder, T J; Tsiolakis, D; Marks, V; Alberti, K G 1979-08-01 Five healthy volunteers and 6 diabetics were given a mixed test meal on two occasions--once with and once without 10 g guar flour. Addition of guar caused a 47% decrease in maximum post-prandial GIP levels, a 48% decrease in blood glucose and a 48% decrease in plasma insulin in normal subjects. In diabetics, addition of guar caused a 30% reduction in maximum post-prandial GIP and 58% decrease in blood glucose. Four normal and 6 diabetic subjects were given a predominantly carbohydrate meal, again with and without 10 g guar. Addition of guar caused a 78% decrease in blood glucose and a 59% decrease in plasma insulin in normal subjects. In diabetics addition of guar caused a 71% decrease in maximum post-prandial plasma GIP and a 68% decrease in blood glucose. Lowering of post-prandial blood glucose, plasma insulin and GIP levels by guar was statistically significant in every case. Addition of guar to the predominantly carbohydrate meal caused a decrease in total plasma GLI in both normal and diabetic subjects but reached statistical significance only in the normal subjects. There was a highly significant correlation (r = 0.83; p less than 0.0005) between peak post-prandial insulin levels in normal subjects and the corresponding plasma GIP concentration. The reduction of GIP or GLI secretion may, therefore, be partly responsible for the smaller rise in plasma insulin observed in normal volunteers when guar is added to meals. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017EPJWC.15702009T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017EPJWC.15702009T">Fully non-inductive plasma start-up with lower-hybrid waves using the outboard-launch and top-launch antennas on the TST-2 spherical tokamak</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Tsujii, Naoto; Takase, Yuichi; Ejiri, Akira; Shinya, Takahiro; Yajima, Satoru; Yamazaki, Hibiki; Togashi, Hiro; Moeller, Charles P.; Roidl, Benedikt; Takahashi, Wataru; Toida, Kazuya; Yoshida, Yusuke 2017-10-01 Removal of the central solenoid is essential to realize an economical spherical tokamak fusion reactor, but non-inductive plasma start-up is a challenge. On the TST-2 spherical tokamak, non-inductive plasma start-up using lower-hybrid (LH) waves has been investigated. Using the capacitively-coupled combline (CCC) antenna installed at the outboard midplane, fully non-inductive plasma current ramp-up up to a quarter of that of the typical Ohmic discharges has been achieved. Although it was desirable to keep the density low during the plasma current ramp-up to avoid the LH density limit, it was recognized that there was a maximum current density that could be carried by a given electron density. Since the density needed to increase as the plasma current was ramped-up, the achievable plasma current was limited by the maximum operational toroidal field of TST-2. The top-launch CCC antenna was installed to access higher density with up-shift of the parallel index of refraction. Numerical analysis of LH current drive with the outboard-launch and top-launch antennas was performed and the results were qualitatively consistent with the experimental observations. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018PPCF...60e5005T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018PPCF...60e5005T">Confinement of laser plasma expansion with strong external magnetic field</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Tang, Hui-bo; Hu, Guang-yue; Liang, Yi-han; Tao, Tao; Wang, Yu-lin; Hu, Peng; Zhao, Bin; Zheng, Jian 2018-05-01 The evolutions of laser ablation plasma, expanding in strong (∼10 T) transverse external magnetic field, were investigated in experiments and simulations. The experimental results show that the magnetic field pressure causes the plasma decelerate and accumulate at the plasma-field interface, and then form a low-density plasma bubble. The saturation size of the plasma bubble has a scaling law on laser energy and magnetic field intensity. Magnetohydrodynamic simulation results support the observation and find that the scaling law (V max ∝ E p /B 2, where V max is the maximum volume of the plasma bubble, E p is the absorbed laser energy, and B is the magnetic field intensity) is effective in a broad laser energy range from several joules to kilo-joules, since the plasma is always in the state of magnetic field frozen while expanding. About 15% absorbed laser energy converts into magnetic field energy stored in compressed and curved magnetic field lines. The duration that the plasma bubble comes to maximum size has another scaling law t max ∝ E p 1/2/B 2. The plasma expanding dynamics in external magnetic field have a similar character with that in underdense gas, which indicates that the external magnetic field may be a feasible approach to replace the gas filled in hohlraum to suppress the wall plasma expansion and mitigate the stimulated scattering process in indirect drive ignition. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li class="active">1</li> <li><a href="#" onclick='return showDiv("page_2");'>2</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_2" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_1");'>1</a></li> <li class="active">2</li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="21"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/17812899','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/17812899">First plasma wave observations at uranus.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Gurnett, D A; Kurth, W S; Scarf, F L; Poynter, R L 1986-07-04 Radio emissions from Uranus were detected by the Voyager 2 plasma wave instrument about 5 days before closest approach at frequencies of 31.1 and 56.2 kilohertz. About 10 hours before closest approach the bow shock was identified by an abrupt broadband burst of electrostatic turbulence at a radial distance of 23.5 Uranus radii. Once Voyager was inside the magnetosphere, strong whistler-mode hiss and chorus emissions were observed at radial distances less than about 8 Uranus radii, in the same region where the energetic particle instruments detected intense fluxes of energetic electrons. Various other plasma waves were also observed in this same region. At the ring plane crossing, the plasma wave instrument detected a large number of impulsive events that are interpreted as impacts of micrometer-sized dust particles on the spacecraft. The maximum impact rate was about 30 to 50 impacts per second, and the north-south thickness of the impact region was about 4000 kilometers. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1433301-excitation-global-plasma-mode-intense-electron-beam-dc-discharge','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1433301-excitation-global-plasma-mode-intense-electron-beam-dc-discharge">Excitation of a global plasma mode by an intense electron beam in a dc discharge</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a> Sydorenko, D.; Kaganovich, I. D.; Ventzek, P. L. G.; ... 2018-01-01 The interaction of an intense electron beam with a finite-length, inhomogeneous plasma is investigated numerically. The plasma density profile is maximal in the middle and decays towards the plasma edges. Two regimes of the two-stream instability are observed. In one regime, the frequency of the instability is the plasma frequency at the density maximum and plasma waves are excited in the middle of the plasma. In the other regime, the frequency of the instability matches the local plasma frequency near the edges of the plasma and the intense plasma oscillations occur near plasma boundaries. The latter regime appears sporadically andmore » only for strong electron beam currents. This instability generates a copious amount of suprathermal electrons. Finally, the energy transfer to suprathermal electrons is the saturation mechanism of the instability.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/1433301-excitation-global-plasma-mode-intense-electron-beam-dc-discharge','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/1433301-excitation-global-plasma-mode-intense-electron-beam-dc-discharge">Excitation of a global plasma mode by an intense electron beam in a dc discharge</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Sydorenko, D.; Kaganovich, I. D.; Ventzek, P. L. G. The interaction of an intense electron beam with a finite-length, inhomogeneous plasma is investigated numerically. The plasma density profile is maximal in the middle and decays towards the plasma edges. Two regimes of the two-stream instability are observed. In one regime, the frequency of the instability is the plasma frequency at the density maximum and plasma waves are excited in the middle of the plasma. In the other regime, the frequency of the instability matches the local plasma frequency near the edges of the plasma and the intense plasma oscillations occur near plasma boundaries. The latter regime appears sporadically andmore » only for strong electron beam currents. This instability generates a copious amount of suprathermal electrons. Finally, the energy transfer to suprathermal electrons is the saturation mechanism of the instability.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19880036618&hterms=Sacramento+CA&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3DSacramento%252C%2BCA','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19880036618&hterms=Sacramento+CA&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3DSacramento%252C%2BCA">Explosive plasma flows in a solar flare</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Zarro, Dominic M.; Canfield, Richard C.; Metcalf, Thomas R.; Strong, Keith T. 1988-01-01 Solar Maximum Mission soft X-ray data and Sacramento Peak Observatory H-alpha observations are combined in a study of the impulsive phase of a solar flare. A blue asymmetry, indicative of upflows, was observed in the coronal Ca XIX line during the soft X-ray rise phase. A red asymmetry, indicative of downflows, was observed simultaneously in chromospheric H-alpha emitted from bright flare kernels during the period of hard X-ray emission. Combining the velocity data with a measurement of coronal electron density, it is shown that the impulsive phase momentum of upflowing soft X-ray-emitting plasma equalled that of the downflowing H-alpha-emitting plasma to within one order of magnitude. In particular, the momentum of the upflowing plasma was 2 x 10 to the 21st g cm/s while that of the downflowing plasma was 7 x 10 to the 21st g cm/s, with a factor of 2 uncertainty on each value. This equality supports the explosive chromospheric evaporation model of solar flares, in which a sudden pressure increase at the footprint of a coronal loop produces oppositely directed flows in the heated plasma. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19780016257&hterms=corruption&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Dcorruption','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19780016257&hterms=corruption&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Dcorruption">Deep space telecommunications and the solar cycle: A reappraisal</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Berman, A. L. 1978-01-01 Observations of density enhancement in the near corona at solar cycle (sunspot) maximum have rather uncritically been interpreted to apply equally well to the extended corona, thus generating concern about the quality of outer planet navigational data at solar cycle maximum. Spacecraft have been deployed almost continuously during the recently completed solar cycle 20, providing two powerful new coronal investigatory data sources: (1) in-situ spacecraft plasma measurements at approximately 1 AU, and (2) plasma effects on monochromatic spacecraft signals at all signal closest approach points. A comprehensive review of these (solar cycle 20) data lead to the somewhat surprising conclusions that for the region of interest of navigational data, the highest levels of charged particle corruption of navigational data can be expected to occur at solar cycle minimum, rather than solar cycle maximum, as previously believed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012PSST...21d2002W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012PSST...21d2002W">Two-photon absorption laser-induced fluorescence measurements of atomic nitrogen in a radio-frequency atmospheric-pressure plasma jet</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Wagenaars, E.; Gans, T.; O'Connell, D.; Niemi, K. 2012-08-01 The first direct measurements of atomic nitrogen species in a radio-frequency atmospheric-pressure plasma jet (APPJ) are presented. Atomic nitrogen radicals play a key role in new plasma medicine applications of APPJs. The measurements were performed with a two-photon absorption laser-induced fluorescence diagnostic, using 206.65 nm laser photons for the excitation of ground-state N atoms and observing fluorescence light around 744 nm. The APPJ was run with a helium gas flow of 1 slm and varying small admixtures of molecular nitrogen of 0-0.7 vol%. A maximum in the measured N concentration was observed for an admixture of 0.25 vol% N2. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22614073-solitary-waves-dusty-plasmas-weak-relativistic-effects-electrons-ions','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22614073-solitary-waves-dusty-plasmas-weak-relativistic-effects-electrons-ions">Solitary waves in dusty plasmas with weak relativistic effects in electrons and ions</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Kalita, B. C., E-mail: bckalita123@gmail.com; Choudhury, M., E-mail: choudhurymamani@gmail.com 2016-10-15 Two distinct classes of dust ion acoustic (DIA) solitary waves based on relativistic ions and electrons, dust charge Z{sub d} and ion-to-dust mass ratio Q’ = m{sub i}/m{sub d} are established in this model of multicomponent plasmas. At the increase of mass ratio Q’ due to increase of relativistic ion mass and accumulation of more negative dust charges into the plasma causing decrease of dust mass, relativistic DIA solitons of negative potentials are abundantly observed. Of course, relativistic compressive DIA solitons are also found to exist simultaneously. Further, the decrease of temperature inherent in the speed of light c causesmore » the nonlinear term to be more active that increases the amplitude of the rarefactive solitons and dampens the growth of compressive solitons for relatively low and high mass ratio Q’, respectively. The impact of higher initial streaming of the massive ions is observed to identify the point of maximum dust density N{sub d} to yield rarefactive relativistic solitons of maximum amplitude.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1989sasf.confP.165S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1989sasf.confP.165S">Plasma parameters and structures of the X4 flare of 19 May 1984 as observed by SMM-XRP.</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Schmelz, J. T.; Saba, J. L. R.; Strong, K. T. The eruption of a large flare on the east limb of the Sun was observed by the X-ray Polychromator (XRP) on board the Solar Maximum Mission (SMM) on 19 May 1984. The XRP Flat Crystal Spectrometer (FCS) made polychromatic soft X-ray images during the preflare, flare and postflare phases. The XRP Bent Crystal Spectrometer (BCS) provided information on the temperature and dynamics of the hot (Te > 8×106K) coronal plasma from spectra integrated spatially over the whole region. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3688204','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3688204">Bovine and porcine heparins: different drugs with similar effects on human haemodialysis</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> 2013-01-01 Background Heparins from porcine and bovine intestinal mucosa differ in their structure and also in their effects on coagulation, thrombosis and bleeding. However, they are used as undistinguishable drugs. Methods We compared bovine and porcine intestinal heparin administered to patients undergoing a particular protocol of haemodialysis. We compared plasma concentrations of these two drugs and also evaluated how they affect patients and the dialyzer used. Results Compared with porcine heparin, bovine heparin achieved only 76% of the maximum plasma concentration as IU mL-1. This observation is consistent with the activities observed in the respective pharmaceutical preparations. When the plasma concentrations were expressed on weight basis, bovine heparin achieved a maximum concentration 1.5 fold higher than porcine heparin. The reduced anticoagulant activity and higher concentration, on weight basis, achieved in the plasma of patients under dialysis using bovine instead of porcine heparin did not affect significantly the patients or the dialyzer used. The heparin dose is still in a range, which confers security and safety to the patients. Discussion Despite no apparent difference between bovine and porcine intestinal heparins in the haemodialysis practice, these two types of heparins should be used as distinct drugs due to their differences in structure and biological effects. Conclusions The reduced anticoagulant activity achieved in the plasma of patients under dialysis using bovine instead of porcine heparin did not affect significantly the patients or the dialyzer. PMID:23763719 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017APS..DPPUM9009M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017APS..DPPUM9009M">Understanding Turbulence using Active and Passive Multipoint Measurements in Laboratory Magnetospheres</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Mauel, M. E.; Abler, M. C.; Qian, T. M.; Saperstein, A.; Yan, J. R. 2017-10-01 In a laboratory magnetosphere, plasma is confined by a strong dipole magnet, and interchange and entropy mode turbulence can be studied and controlled in near steady-state conditions. Turbulence is dominated by long wavelength modes exhibiting chaotic dynamics, intermitency, and an inverse spectral cascade. Here, we summarize recent results: (i) high-resolution measurement of the frequency-wavenumber power spectrum using Capon's ``maximum likelihood method'', and (ii) direct measurement of the nonlinear coupling of interchange/entropy modes in a turbulent plasma through driven current injection at multiple locations and frequencies. These observations well-characterize plasma turbulence over a broad band of wavelengths and frequencies. Finally, we also discuss the application of these techniques to space-based experiments and observations aimed to reveal the nature of heliospheric and magnetospheric plasma turbulence. Supported by NSF-DOE Partnership in Plasma Science Grant DE-FG02-00ER54585. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016REDS..171..421S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016REDS..171..421S">Structural, morphological and mechanical properties of niobium nitride thin films grown by ion and electron beams emanated from plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Siddiqui, Jamil; Hussain, Tousif; Ahmad, Riaz; Umar, Zeeshan A.; Abdus Samad, Ubair 2016-05-01 The influence of variation in plasma deposition parameters on the structural, morphological and mechanical characteristics of the niobium nitride films grown by plasma-emanated ion and electron beams are investigated. Crystallographic investigation made by X-ray diffractometer shows that the film synthesized at 10 cm axial distance with 15 plasma focus shots (PFS) exhibits better crystallinity when compared to the other deposition conditions. Morphological analysis made by scanning electron microscope reveals a definite granular pattern composed of homogeneously distributed nano-spheroids grown as clustered particles for the film synthesized at 10 cm axial distance for 15 PFS. Roughness analysis demonstrates higher rms roughness for the films synthesized at shorter axial distance and by greater number of PFS. Maximum niobium atomic percentage (35.8) and maximum average hardness (19.4 ± 0.4 GPa) characterized by energy-dispersive spectroscopy and nano-hardness analyzer respectively are observed for film synthesized at 10 cm axial distance with 15 PFS. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010cosp...38.2896S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010cosp...38.2896S">Evolution of plasma characteristics for weak X-ray brightenings seen by SphinX during recent deep minimum of solar activity</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Sylwester, Barbara; Sylwester, Janusz; Siarkowski, Marek; Gburek, Szymon; Phillips, Kenneth Very high sensitivity of SphinX soft X-ray spectrophotometer aboard Coronas-Photon allows to observe spectra of small X-ray brightenings(microflares), many of them with maximum intensities well below the GOES or RHESSI sensitivity thresholds. Hundreds of such small flare-like events have been observed in the period between March and November 2009 with energy resolution better than 0.5 keV. The spectra have been measured in the energy range extending above 1 keV. In this study we investigate the time variability of basic plasma parameters: temperature T and emission measure EM for a number of these weak flare-like events and discuss respective evolutionary patterns on the EM-T diagnostic diagrams. For some of these events, unusual behavior is observed, different from this characteristic for a "normal" flares of higher maximum intensities. Physical scenarios providing possible explanation of such unusual evolutionary patterns will be discussed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19850015960','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19850015960">Ultraviolet Spectrometer and Polarimeter (UVSP) software development and hardware tests for the solar maximum mission</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> 1984-01-01 An analysis of UVSP wavelength drive hardware, problems, and recovery procedures; radiative power loss from solar plasmas; and correlations between observed UV brightness and inferred photospheric currents are given. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016ApPhL.108g4103T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016ApPhL.108g4103T">Neutral-depletion-induced axially asymmetric density in a helicon source and imparted thrust</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Takahashi, Kazunori; Takao, Yoshinori; Ando, Akira 2016-02-01 The high plasma density downstream of the source is observed to be sustained only for a few hundreds of microsecond at the initial phase of the discharge, when pulsing the radiofrequency power of a helicon plasma thruster. Measured relative density of argon neutrals inside the source implies that the neutrals are significantly depleted there. A position giving a maximum plasma density temporally moves to the upstream side of the source due to the neutral depletion and then the exhausted plasma density significantly decreases. The direct thrust measurement demonstrates that the higher thrust-to-power ratio is obtained by using only the initial phase of the high density plasma, compared with the steady-state operation. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15894529','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15894529">Cassini measurements of cold plasma in the ionosphere of Titan.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Wahlund, J E; Boström, R; Gustafsson, G; Gurnett, D A; Kurth, W S; Pedersen, A; Averkamp, T F; Hospodarsky, G B; Persoon, A M; Canu, P; Neubauer, F M; Dougherty, M K; Eriksson, A I; Morooka, M W; Gill, R; André, M; Eliasson, L; Müller-Wodarg, I 2005-05-13 The Cassini Radio and Plasma Wave Science (RPWS) Langmuir probe (LP) sensor observed the cold plasma environment around Titan during the first two flybys. The data show that conditions in Saturn's magnetosphere affect the structure and dynamics deep in the ionosphere of Titan. The maximum measured ionospheric electron number density reached 3800 per cubic centimeter near closest approach, and a complex chemistry was indicated. The electron temperature profiles are consistent with electron heat conduction from the hotter Titan wake. The ionospheric escape flux was estimated to be 10(25) ions per second. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013JGRA..118.3613L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013JGRA..118.3613L">Observation of F region irregularities near a northern equatorial anomaly crest during solar minimum using ionosonde, GPS receiver, and satellites</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Lee, C.-C.; Chen, W. S.; Chu, F. D. 2013-06-01 For solar minimum, the spread F, GPS phase fluctuations, and plasma bubbles near the crest of equatorial ionization anomaly (EIA) are simultaneously analyzed to investigate F region irregularities for the first time. The data were observed using the Chungli ionosonde, YMSM GPS receiver, and DMSP satellites during 1996. It is found that in the observed ionograms, the frequency spread F (FSF) usually comes after the range spread F (RSF) in a series of nighttime spread F events. This results in that the maximum occurrence of RSF appears before that of FSF in the nighttime variations in occurrence probabilities. Moreover, the seasonal variation for RSF is close to that for FSF. Both have a board maximum in the J-months and a secondary maximum in December. These indicate that RSF and FSF should be regarded as one type of spread F, which is the all spread F (ASF) in this study. Because the equatorial plasma bubbles occur infrequently during solar minimum, the F region irregularities forming ASF are not related to the equatorial spread F. On the other hand, the similarity in seasonal occurrence between ASF and medium-scale traveling ionospheric disturbances (MSTIDs) demonstrates that the F region irregularities near the EIA crest are mainly generated by the gradient drift instability driven by MSTIDs. The irregularities, generated by MSTIDs, mostly occur in the bottom side of the F region. Consequently, the events of significant GPS phase fluctuations and plasma bubble near the EIA crest are rare during 1996. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20010023031&hterms=oxygen+planets&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Doxygen%2Bplanets','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20010023031&hterms=oxygen+planets&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Doxygen%2Bplanets">Finite Gyroradius Effects Observed in Pickup Oxygen Ions at Venus</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Hartle, Richard E.; Intriligator, Devrie; Grebowsky, Joseph M.; Einaudi, Franco (Technical Monitor) 2000-01-01 On the dayside of Venus, the hot oxygen corona extending above the ionopause is the principal source of pickup oxygen ions. The ions are born here and picked up by the ionosheath plasma as it is deflected around the planet. These pickup ions have been observed by the Orbiter Plasma Analyzer (OPA) throughout the Pioneer Venus Orbiter (PVO) mission. They were observed over a region extending from their dayside source to great distances downstream (about 10 Venus radii), in the solar wind wake, as PVO passed through apoapsis. Finite gyroradius effects in the velocity distribution of the oxygen pickup ions are expected in the source region because the gyroradius is several times larger than the scale height of the hot oxygen source. Such effects are also expected in those regions of the ionosheath where the scale lengths of the magnetic field and the ambient plasma velocity field are less than the pickup ion gyroradius. While explicitly accounting for the spatial distribution of the hot oxygen source, an analytic expression for the pickup oxygen ion velocity distribution is developed to study how it is affected by finite gyroradii. The analysis demonstrates that as the gyroradius increases by factors of three to six above the hot oxygen scale height, the peak of the pickup oxygen ion flux distribution decreases 25 to 50% below the maximum allowed speed, which is twice the speed of the ambient plasma times the sine of the angle between the magnetic field and the flow velocity. The pickup oxygen ion flux distribution observed by OPA is shown to follow this behavior in the source region. It is also shown that this result is consistent with the pickup ion distributions observed in the wake, downstream of the source, where the flux peaks are usually well below the maximum allowed speed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017PhPl...24i2108K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017PhPl...24i2108K">Effect of ion beam on the characteristics of ion acoustic Gardner solitons and double layers in a multicomponent superthermal plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kaur, Nimardeep; Singh, Kuldeep; Saini, N. S. 2017-09-01 The nonlinear propagation of ion acoustic solitary waves (IASWs) is investigated in an unmagnetized plasma composed of a positive warm ion fluid, two temperature electrons obeying kappa type distribution and penetrated by a positive ion beam. The reductive perturbation method is used to derive the nonlinear equations, namely, Korteweg-de Vries (KdV), modified KdV (mKdV), and Gardner equations. The characteristic features of both compressive and rarefactive nonlinear excitations from the solution of these equations are studied and compared in the context with the observation of the He+ beam in the polar cap region near solar maximum by the Dynamics Explorer 1 satellite. It is observed that the superthermality and density of cold electrons, number density, and temperature of the positive ion beam crucially modify the basic properties of compressive and rarefactive IASWs in the KdV and mKdV regimes. It is further analyzed that the amplitude and width of Gardner solitons are appreciably affected by different plasma parameters. The characteristics of double layers are also studied in detail below the critical density of cold electrons. The theoretical results may be useful for the observation of nonlinear excitations in laboratory and ion beam driven plasmas in the polar cap region near solar maximum and polar ionosphere as well in Saturn's magnetosphere, solar wind, pulsar magnetosphere, etc., where the population of two temperature superthermal electrons is present. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2007AGUFMSM14A..07E','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2007AGUFMSM14A..07E">Plasma jets and FTE Dayside Generation for Northward IMF on 8 June 2007: THEMIS Observations</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Eriksson, S.; Cully, C. M.; Ergun, R. E.; Gosling, J. T.; Angelopoulos, V.; Bonnell, J. W.; McFadden, J. P.; Glassmeier, K.; Roux, A.; Auster, H.; Le Contel, O. 2007-12-01 Five-spacecraft THEMIS (TH) observations are presented for a 15.5 MLT equatorial magnetopause crossing on 8 June 2007 when the upstream IMF was predominantly northward with a negative IMF By component at Wind. During the 0650-0855 UT period on this day TH-B was the most tailward probe while TH-A was the most sunward probe. TH-E was closest to TH-A with a maximum separation of only 0.71 RE. The maximum TH-A to TH-B GSM separation was 1.85 RE. TH-B showed a clean magnetopause crossing into the magnetosphere as the magnetopause expanded over the probes while TH-A spent this 2-hour period within a boundary layer inside the magnetopause with frequent transitions between a magnetosheath-like and a magnetosphere-like plasma as previously seen by Cluster at high-latitudes for southward IMF [Wild et al., 2003]. TH-E observed similar activity for a shorter period of time. Many of the sheath-like transitions showed evidence of plasma jets at TH-A with enhanced speed in the tailward and/or duskward direction suggesting a subsolar component merging region. Some jets were related to frequent bipolar FTE signatures in the normal BN component with enhanced total pressure observed at their centers. The more common ±BN sequence suggests that TH-A observed tailward propagating FTEs on the sheath side of the magnetopause. We compare TH-E ExB velocities with the enhanced jet velocities observed by TH-A and discuss whether the jets observed within this boundary layer were caused by subsolar magnetopause reconnection. We also compare these low-latitude northward IMF observations with prior Cluster FTE observations at high-latitude for southward IMF. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16605836','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16605836">Inductive and electrostatic acceleration in relativistic jet-plasma interactions.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Ng, Johnny S T; Noble, Robert J 2006-03-24 We report on the observation of rapid particle acceleration in numerical simulations of relativistic jet-plasma interactions and discuss the underlying mechanisms. The dynamics of a charge-neutral, narrow, electron-positron jet propagating through an unmagnetized electron-ion plasma was investigated using a three-dimensional, electromagnetic, particle-in-cell computer code. The interaction excited magnetic filamentation as well as electrostatic plasma instabilities. In some cases, the longitudinal electric fields generated inductively and electrostatically reached the cold plasma-wave-breaking limit, and the longitudinal momentum of about half the positrons increased by 50% with a maximum gain exceeding a factor of 2 during the simulation period. Particle acceleration via these mechanisms occurred when the criteria for Weibel instability were satisfied. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_1");'>1</a></li> <li class="active">2</li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_3" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_1");'>1</a></li> <li><a href="#" onclick='return showDiv("page_2");'>2</a></li> <li class="active">3</li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="41"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017ARep...61..513A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017ARep...61..513A">Distribution of interstellar plasma in the direction of PSR B0525+21 from data obtained on a ground-space interferometer</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Andrianov, A. S.; Smirnova, T. V.; Shishov, V. I.; Gwinn, C.; Popov, M. V. 2017-06-01 Observations on the RadioAstron ground-space interferometer with the participation of the Green Bank and Arecibo ground telescopes at 1668 MHz have enabled studies of the characteristics of the interstellar plasma in the direction of the pulsar PSR B0525+21. The maximum projected baseline for the ground-space interferometer was 233 600 km. The scintillations in these observations were strong, and the spectrum of inhomogeneties in the interstellar plasma was a power law with index n = 3.74, corresponding to a Kolmogorov spectrum. A new method for estimating the size of the scattering disk was applied to estimate the scattering angle (scattering disk radius) in the direction toward PSR B0525+21, θ scat = 0.028 ± 0.002 milliarcsecond. The scattering in this direction occurs in a plasma layer located at a distance of 0.1 Z from the pulsar, where Z is the distance from the pulsar to the observer. For the adopted distance Z = 1.6 kpc, the screen is located at a distance of 1.44 kpc from the observer. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19830014037','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19830014037">STS-3/OSS-1 Plasma Diagnostics Package (PDP) measurements of Orbiter transmitter and subsystem electromagnetic interference</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Shawhan, S. D.; Murphy, G. 1983-01-01 The plasma diagnostics package receiver system is described to identify the various antennas and to characterize the complement of receivers which cover the frequency range of 30 Hz to 800 Hz and S-band at 2200 + or - 300 MHz. Sample results are presented to show the variability of electromagnetic effects associated with the orbiter and the time variability of these effects. The electric field and magnetic field maximum and minimum field strength spectra observed during the mission at the pallet location are plotted. Values are also derived for the maximum UHF transmitter and S-band transmitter field strengths. Calibration data to convert from the survey plots to actual narrowband and broadband field strengths are listed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFMSA51A2384L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFMSA51A2384L">A new method of derived equatorial plasma bubbles motion by tracing OI 630 nm emission all-sky images</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Li, M.; Yu, T.; Chunliang, X.; Zuo, X.; Liu, Z. 2017-12-01 A new method for estimating the equatorial plasma bubbles (EPBs) motions from airglow emission all-sky images is presented in this paper. This method, which is called 'cloud-derived wind technology' and widely used in satellite observation of wind, could reasonable derive zonal and meridional velocity vectors of EPBs drifts by tracking a series of successive airglow 630.0 nm emission images. Airglow emission images data are available from an all sky airglow camera in Hainan Fuke (19.5°N, 109.2°E) supported by China Meridional Project, which can receive the 630.0nm emission from the ionosphere F region at low-latitudes to observe plasma bubbles. A series of pretreatment technology, e.g. image enhancement, orientation correction, image projection are utilized to preprocess the raw observation. Then the regions of plasma bubble extracted from the images are divided into several small tracing windows and each tracing window can find a target window in the searching area in following image, which is considered as the position tracing window moved to. According to this, velocities in each window are calculated by using the technology of cloud-derived wind. When applying the cloud-derived wind technology, the maximum correlation coefficient (MCC) and the histogram of gradient (HOG) methods to find the target window, which mean to find the maximum correlation and the minimum euclidean distance between two gradient histograms in respectively, are investigated and compared in detail. The maximum correlation method is fianlly adopted in this study to analyze the velocity of plasma bubbles because of its better performance than HOG. All-sky images from Hainan Fuke, between August 2014 and October 2014, are analyzed to investigate the plasma bubble drift velocities using MCC method. The data at different local time at 9 nights are studied and find that zonal drift velocity in different latitude at different local time ranges from 50 m/s to 180 m/s and there is a peak value at about 20°N. For comparison and validation, EPBs motions obtained from three traditional methods are also investigated and compared with MC method. The advantages and disadvantages of using cloud-derived wind technology to calculate EPB drift velocity are discussed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27877982','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27877982">Phase formation in selected surface-roughened plasma-nitrided 304 austenite stainless steel.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Singh, Gajendra Prasad; Joseph, Alphonsa; Raole, Prakash Manohar; Barhai, Prema Kanta; Mukherjee, Subroto 2008-04-01 Direct current (DC) glow discharge plasma nitriding was carried out on three selected surface-roughened AISI 304 stainless steel samples at 833 K under 4 mbar pressures for 24 h in the presence of N 2 :H 2 gas mixtures of 50 : 50 ratios. After plasma nitriding, the phase formation, case depth, surface roughness, and microhardness of a plasma-nitrided layer were evaluated by glancing angle x-ray diffractogram, optical microscope, stylus profilometer, and Vickers microhardness tester techniques. The case depth, surface hardness, and phase formation variations were observed with a variation in initial surface roughness. The diffraction patterns of the plasma-nitrided samples showed the modified intensities of the α and γ phases along with those of the CrN, Fe 4 N, and Fe 3 N phases. Hardness and case depth variations were observed with a variation in surface roughness. A maximum hardness of 1058 Hv and a case depth of 95 μm were achieved in least surface-roughened samples. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AIPC.1824c0016S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AIPC.1824c0016S">Localized normalization for improved calibration curves of manganese and zinc in laser-induced plasma spectroscopy</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Sabri, Nursalwanie Mohd; Haider, Zuhaib; Tufail, Kashif; Imran, Muhammad; Ali, Jalil 2017-03-01 Laser-induced plasma spectroscopy is performed to determine the elemental compositions of manganese and zinc in potassium bromide (KBr) matrix. This work has utilized Q-switched Nd:YAG laser installed in LIBS2500plus system at fundamental wavelength. The pelletized sample were ablated in air with maximum laser energy of 650 mJ for different gate delays ranging from 0-18 µs. The spectra of samples are obtained for five different compositions containing preferred spectral lines. The intensity of spectral line is observed at its maximum at a gate-delay 0.83 µs and subsequently decayed exponentially with the increasing of gate delay. Maximum signal-to-background ratio of Mn and Zn were found at gate delays of 7.92 and 7.50 µs, respectively. Initial calibration curves show bad data fitting, whereas the locally normalized intensity for both spectral lines shows enhancement since it is more linearly regressed. This study will give a better understanding in studying the plasma emission and the spectra analysis. At the request of all authors of the paper, and with the agreement of the Proceedings Editor, an updated version of this article was published on 24 May 2017. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19840056766&hterms=polska&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D20%26Ntt%3Dpolska','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19840056766&hterms=polska&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D20%26Ntt%3Dpolska">A multiwavelength study of a double impulsive flare</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Strong, K. T.; Benz, A. O.; Dennis, B. R.; Poland, A. I.; Leibacher, J. W.; Mewe, R.; Schrijver, J.; Simnett, G.; Smith, J. B., Jr.; Sylwester, J. 1984-01-01 Solar Maximum Mission (SMM) and ground-based observations are given for two flares which occurred 3 min apart in the same section of the active region. The physical characteristics of the two flares are derived and compared, and the main difference between them is noted to be in the preflare state of the coronal plasma at the flare site. These data suggest that the plasma filling the flaring loops absorbed most of the energy released during the impulsive phase of the second flare, so that only a fraction of the energy could reach the chromosphere to produce mass motions and turbulence. Since a study of the brightest flares observed by SMM shows that at least 43 percent of them are multiple, the situation presently studied may be quite common, and the difference in initial plasma conditions could explain at least some of the large variations in observed flare parameters. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23103683','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23103683">Tunable bandgap energy of fluorinated nanocrystals for flash memory applications produced by low-damage plasma treatment.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Huang, Chi-Hsien; Lin, Chih-Ting; Wang, Jer-Chyi; Chou, Chien; Ye, Yu-Ren; Cheng, Bing-Ming; Lai, Chao-Sung 2012-11-30 A plasma system with a complementary filter to shield samples from damage during tetrafluoromethane (CF(4)) plasma treatment was proposed in order to incorporate fluorine atoms into gadolinium oxide nanocrystals (Gd(2)O(3)-NCs) for flash memory applications. X-ray photoelectron spectroscopy confirmed that fluorine atoms were successfully introduced into the Gd(2)O(3)-NCs despite the use of a filter in the plasma-enhanced chemical vapour deposition system to shield against several potentially damaging species. The number of incorporated fluorine atoms can be controlled by varying the treatment time. The optimized memory window of the resulting flash memory devices was twice that of devices treated by a filterless system because more fluorine atoms were incorporated into the Gd(2)O(3)-NCs film with very little damage. This enlarged the bandgap energy from 5.48 to 6.83 eV, as observed by ultraviolet absorption measurements. This bandgap expansion can provide a large built-in electric field that allows more charges to be stored in the Gd(2)O(3)-NCs. The maximum improvement in the retention characteristic was >60%. Because plasma damage during treatment is minimal, maximum fluorination can be achieved. The concept of simply adding a filter to a plasma system to prevent plasma damage exhibits great promise for functionalization or modification of nanomaterials for advanced nanoelectronics while introducing minimal defects. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1429030','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1429030">Studies on the absorption and disposition of meptazinol following rectal administration.</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Franklin, R A; Southgate, P J; Coleman, A J 1977-01-01 1 Rectal administration of the new analgesic drug, meptazinol, resulted in rapid absorption of the compound both in the monkey and in man. Peak plasma levels were observed within 0.5 h of dosing. 2 Absorption of the drug following rectal administration was extensive as shown by the recovery of 65-90% of the dose in the urine. 3 Despite substantial inter-individual variation in the observed maximum plasma concentrations of the drug, it was still evident that concentrations after rectal dosage were considerably higher than when the same dosage was given orally. 4 Elimination of the drug from plasma took place rapidly in an apparently mono-exponential manner in both species. The half-life of elimination in monkeys was 1.25 h and in man 2.0 h. PMID:405029 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2008cosp...37..525C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2008cosp...37..525C">Observations of weak ionosphere disturbances on the Kharkov incoherent scatter radar</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Cherniak, Iurii; Lysenko, Valery; Cherniak, Iurii The ionosphere plasma characteristics are responding on variations of solar and magnetic activity, high-power processes in the Earth atmosphere and lithosphere. The research of an ionosphere structure and dynamics is important as for understanding physics of processes and radiophysical problems solution. The method of incoherent scatter (IS) of radiowaves allows determining experimentally as regular variations of electronic concentration Ne and concomitant ionosphere parameters, and their behaviour during natural and antropogeneous origin disturbances. The equipment and measurement technique, developed by authors, are allows obtaining reliable data about an ionosphere behaviour during various origin and intensity perturbations. Oservations results of main parameters IS signal and ionosphere plasma during weak magnetic storm, solar eclipse, ionosphere disturbances caused by start of the high-power rocket are presented. Experimentally obtained on the Kharkov IS radar altitude-temporary dependences of disturbed ionosphere plasma parameters during weak intensity magnetic storm 04-06 April 2006 (Kp = 5, Dst = -100 nTl) were adduced. During a main storm phase the positive perturbation was observed (Ne is increased in 1.3 times), April 5, at maximum Dst - negative perturbation (Ne is decreased in 1.6 times), April 6 - positive perturbation (the second positive storm phase - Ne was increased at 1.33 times). During negative ionosphere storm the height of a F2 layer maximum was increased on 30-40 km, ionic temperature in the day is increased on 150K, electronic temperature is increased on 600K. For date 29.03.2006, when take place partial Sun eclipse (disk shadow factor 73 During launch heavy class rocket "Proton-K" december 25, 2006 from Baikonur cosmodrome (distance up to a view point of 2500 km) the perturbations in close space were observed. By measurements results of ionosphere plasma cross-section two disturbed areas were registered. First was observed through 8 mines, and second - through 60 mines after start of the rocket. The altitude-temporary diagrams of ionosphere plasma cross-section distribution were adduced. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27806005','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27806005">Effect of 1 Repetition Maximum, 80% Repetition Maximum, and 50% Repetition Maximum Strength Exercise in Trained Individuals on Variations in Plasma Redox Biomarkers.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Polotow, Tatiana G; Souza-Junior, Tácito P; Sampaio, Ricardo C; Okuyama, Alexandre R; Ganini, Douglas; Vardaris, Cristina V; Alves, Ragami C; McAnulty, Steven R; Barros, Marcelo P 2017-09-01 Polotow, TG, Souza-Junior, TP, Sampaio, RC, Okuyama, AR, Ganini, D, Vardaris, CV, Alves, RC, McAnulty, SR, and Barros, MP. Effect of 1RM, 80%RM, and 50%RM strength exercise in trained individuals on variations in plasma redox biomarkers. J Strength Cond Res 31(9): 2489-2497, 2017-For decades, scientists have examined the participation of oxygen/nitrogen species in anaerobic-like exercises, especially weightlifting and resistance exercises. The balance between the production of oxyradicals and antioxidant responses during anaerobic-like exercises is essential to assure adaptation to the physiological benefits of strength training and to prevent chronic harmful effects. The aim of this study is to examine the hypothesis that different weight loads (1 repetition maximum (RM), 80%RM, and 50%RM) lifted until exhaustion could impose distinct oxidative insults and elicit diverse antioxidant responses in plasma of young trained subjects. Glucose (+10%), lactate (+65%), urea (+30%), free iron (+65%), reduced/oxidized glutathione (+14 and +23%, respectively), and xanthine oxidase activity (2.2-fold) significantly increased after the 1RM test, whereas plasma antioxidant capacity dropped by 37%. When lower weight loads were applied (80%RM and 50%RM tests), heme-iron (+15 and +20%, respectively) became the prevalent pro-oxidant, although glutathione responses were only detected after 80%RM (+14%). Lactate concentration in plasma continuously increased, by 2.9-fold (80%RM) and 3.6-fold higher (50%RM test). We demonstrated that 1RM tests significantly diminish the antioxidant capacity of plasma because of iron overload, whereas 80%RM tests require higher involvement of glutathione molecules to counteract heme-iron oxidative insult. Mild redox imbalances promoted by heme-iron were found in plasma after 50%RM. Although we did not observe overall changes in muscle damage in young trained subjects, we cannot exclude the need for specific antioxidant supplementation depending on the strength protocols applied, especially for less responsive groups, such as sedentary and elderly populations. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29378154','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29378154">Plasma dispositions and concentrations of ivermectin in eggs following treatment of laying hens.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Cirak, V Y; Aksit, D; Cihan, H; Gokbulut, C 2018-05-01 To determine the plasma disposition and concentrations of ivermectin (IVM) in eggs produced by laying hens following S/C, oral and I/V administration. Twenty-four laying hens, aged 37 weeks and weighing 1.73 (SD 0.12) kg were allocated to three groups of eight birds. The injectable formulation of IVM was administered either orally, S/C, or I/V, at a dose of 0.2 mg/kg liveweight, following dilution (1:5, v/v) with propylene glycol. Heparinised blood samples were collected at various times between 0.25 hours and 20 days after drug administration. Eggs produced by hens were also collected daily throughout the study period. Samples of plasma and homogenised egg were analysed using HPLC. Maximum concentrations of IVM in plasma and mean residence time of IVM were lower after oral (10.2 (SD 7.2) ng/mL and 0.38 (SD 0.14) days, respectively) than after S/C (82.9 (SD 12.4) ng/mL and 1.05 (SD 0.24) days, respectively) administration (p<0.01). The time to maximum concentration and elimination half-life were shorter following oral (0.14 (SD 0.04) and 0.23 (SD 0.11) days, respectively) than S/C (0.25 (SD 0.00) and 1.45 (SD 0.45) days, respectively) administration (p<0.01). IVM was first detected in eggs 2 days after treatment in all groups and was detected until 8 days after oral and I/V administration, and until 15 days after S/C administration. Peak concentrations of IVM were 15.7, 23.3 and 1.9 µg/kg, observed 2, 5 and 4 days after I/V, S/C and oral administration, respectively. The low plasma bioavailability of IVM observed after oral administration in laying hens could result in lower efficacy or subtherapeutic plasma concentrations, which may promote the development of parasitic drug resistance. Due to high IVM residues in eggs compared to the maximum residue limits for other food-producing animal species, a withdrawal period should be necessary for eggs after IVM treatment in laying hens. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19740020497&hterms=incubation&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dincubation','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19740020497&hterms=incubation&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dincubation">Change in blood coagulation indices as a function of the incubation period of plasma in a constant magnetic field. [considering heparin tolerance and recalcification</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Yepishina, S. G. 1974-01-01 The influence of a constant magnetic field (CMF) with a strength of 250 and 2500 oersteds on the recalcification reaction and the tolerance of plasma to heparin was studied as a function of the exposure time of the plasma to the CMF. The maximum and reliable change in the activation of the coagulatory system of the blood was observed after a 20-hour incubation of the plasma in a CMF. As the exposure time increased, the recalcification reaction changed insigificantly; the difference between the mean arithmetic of the experiment and control values was not statistically reliable. The tolerance of the plasma to heparin as a function of the exposure time to the CMF of the plasma was considerably modified, an was statistically reliable. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22849510','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22849510">Pharmacokinetics and pharmacodynamics of edivoxetine (LY2216684), a norepinephrine reuptake inhibitor, in pediatric patients with attention-deficit/hyperactivity disorder.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Kielbasa, William; Quinlan, Tonya; Jin, Ling; Xu, Wen; Lachno, D Richard; Dean, Robert A; Allen, Albert J 2012-08-01 Edivoxetine (LY2216684) is a selective and potent norepinephrine reuptake inhibitor (NERI). The pharmacokinetics (PK) and pharmacodynamics (PD) of edivoxetine were assessed in children and adolescent patients with attention-deficit/hyperactivity disorder (ADHD) following single and once-daily oral doses of edivoxetine. During a phase 1 open-label safety, tolerability, and PK study, pediatric patients were administered edivoxetine at target doses of 0.05, 0.1, 0.2 and 0.3 mg/kg, and blood samples were collected to determine plasma concentrations of edivoxetine for PK assessments and plasma 3,4-dihydroxyphenylglycol (DHPG) concentrations for PD assessments. Edivoxetine plasma concentrations were measured using liquid chromatography with tandem mass spectrometric detection, and DHPG was measured using liquid chromatography with electrochemical detection. Edivoxetine PK was comparable between children and adolescents. The time to maximum concentration (t(max)) of edivoxetine was ∼2 hours, which was followed by a mono-exponential decline in plasma concentrations with a terminal elimination half-life (t(1/2)) of ∼6 hours. Dose-dependent increases in area under the edivoxetine plasma concentration versus time curve from zero to infinity (AUC(0-∞)) and maximum plasma concentration (C(max)) were observed, and there was no discernable difference in the apparent clearance (CL/F) or the apparent volume of distribution at steady state (V(ss)/F) across the dose range. In adolescents, edivoxetine caused a maximum decrease in plasma DHPG concentrations from baseline of ∼28%, most notably within 8 hours of edivoxetine administration. This initial study in pediatric patients with ADHD provides new information on the PK profile of edivoxetine, and exposures that decrease plasma DHPG consistent with the mechanism of action of a NERI. The PK and PD data inform edivoxetine pharmacology and can be used to develop comprehensive population PK and/or PK-PD models to guide dosing strategies. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017xru..conf..330T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017xru..conf..330T">X-ray Spectral Analysis of the Cataclysmic Variable LS Peg using XMM-Newton Observatory Data</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Talebpour Sheshvan, N.; Nabizadeh, A.; Balman, S. 2017-10-01 LS Peg is a Cataclysmic Variable (CV) suggested as Intermediate Polar (IP) because of similar properties to those observed in IP systems. We used archival XMM-Newton observation of LS Peg in order to study the X-ray characteristics of the system. We show LS Peg light curves in several different energy bands, and discuss about orbital modulations and power spectral analysis. Unlike the previous spectral analysis of the EPIC-MOS data by fitting a hot optically thin plasma emission model with a single temperature, we simultaneously fit EPIC spectrum (pn+MOS) using a composite model of absorption (tbabs) along with two different partial covering absorbers plus a multi-temperature plasma emission component in XSPEC. In addition, we find a Gaussian emission line at 6.4 keV. For LS Peg the maximum temperature of the plasma distribution is found to be ˜ 17.8 keV with a luminosity of ˜ 7.4×10^{32}erg s^{-1} translating to an accretion rate of ˜ 1.7×10 ^{-10} M_{⊙} yr^{-1}. We present spectra for orbital minimum and orbital maximum. In addition, we use SWIFT observations of the source in order to make a comparison. We elaborate on the geometry of accretion and absorption in the X-ray emitting region with articulation on the magnetic nature. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19950029887&hterms=coma&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3Dcoma','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19950029887&hterms=coma&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3Dcoma">Rosat observations of FK comae berenices</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Welty, Alan D.; Ramsey, Lawrence W. 1994-01-01 We obtained ROSAT PSPC observations of FK Com over a period of 24.4 h, or 0.42 rotation. During the observations the x-ray flux increased by a factor of at least 5 before declining toward its previous level. A single temperature Raymond-Smith model is adequate to model the low signal-to-noise ratio spectrum from each observation interval. Initially the spectrum was that of a 8.5 x 10(exp 6) K plasma, with L9sub x)=0.66 x 10(exp 31) erg s(exp -1). When the x-ray flux was greatest, the model plasma temperature rose to 2.5 x 10(exp 7) K, and L(sub x)=3.46 x 10(exp 31) ergs(exp -1). During the post-maximum decline in luminosity the plasma temperature was approximately 12 x 10(exp 6) K. We conclude that the increase of x-ray flux recorded by ROSAT was due to an x-ray flare with a 1.5 h decline time scale. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19990008044&hterms=astronomia+espacio&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3Dastronomia%2By%2Bespacio','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19990008044&hterms=astronomia+espacio&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3Dastronomia%2By%2Bespacio">Ultraviolet Events Observed in Active Regions. 2; An Interpretation of Flaring Arches and Associated Small Flares</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Fontenla, J.; Rovira, M.; Tandberg-Hanssen, E. 1997-01-01 We analyze Hz, UV, and X-ray emissions in and around the spectacular arch system seen in the corona on 1980 March 27 during the Solar Maximum Mission. The flaring of the arch plasma is studied, and its dependence on triggering mechanisms related to the observed small limb flare in the arch footpoint is analyzed. To drive these events, we propose a mechanism in which small electric current circuits and the localized magnetic free energy are continuously generated at a magnetic null by a pressure gradient, which then compress or expand the plasma. This free energy dissipates by Joule effect and upward transport. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1436768-magnetic-polarization-measurements-multi-modal-plasma-response-fields-east-tokamak','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1436768-magnetic-polarization-measurements-multi-modal-plasma-response-fields-east-tokamak">Magnetic Polarization Measurements of the Multi-modal Plasma Response to 3D fields in the EAST Tokamak</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a> Logan, Nikolas; Cui, L.; Wang, Hui -Hui; ... 2018-04-30 A multi-modal plasma response to applied non-axisymmetric fields has been found in EAST tokamak plasmas. Here, multi-modal means the radial and poloidal structure of an individually driven toroidal harmonic is not fixed. The signature of such a multi-modal response is the magnetic polarization (ratio of radial and poloidal components) of the plasma response field measured on the low field side device mid-plane. A difference in the 3D coil phasing (the relative phase of two coil arrays) dependencies between the two responses is observed in response to n=2 fields in the same plasma for which the n=1 responses are well synchronized.more » Neither the maximum radial nor the maximum poloidal field response to n=2 fields agrees with the best applied phasing for mitigating edge localized modes, suggesting that the edge plasma response is not a dominant component of either polarization. GPEC modeling reproduces the discrepant phasing dependences of the experimental measurements, and confirms the edge resonances are maximized by the coil phasing that mitigates ELMs in the experiments. The model confirms the measured plasma response is not dominated by resonant current drive from the external field. Instead, non-resonant contributions play a large role in the diagnostic signal for both toroidal harmonics n=1 and n=2. The analysis in this paper demonstrates the ability of 3D modeling to connect external magnetic sensor measurements to the internal plasma physics and accurately predict optimal applied 3D field configurations in multi-modal plasmas.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/1436768-magnetic-polarization-measurements-multi-modal-plasma-response-fields-east-tokamak','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/1436768-magnetic-polarization-measurements-multi-modal-plasma-response-fields-east-tokamak">Magnetic Polarization Measurements of the Multi-modal Plasma Response to 3D fields in the EAST Tokamak</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Logan, Nikolas; Cui, L.; Wang, Hui -Hui A multi-modal plasma response to applied non-axisymmetric fields has been found in EAST tokamak plasmas. Here, multi-modal means the radial and poloidal structure of an individually driven toroidal harmonic is not fixed. The signature of such a multi-modal response is the magnetic polarization (ratio of radial and poloidal components) of the plasma response field measured on the low field side device mid-plane. A difference in the 3D coil phasing (the relative phase of two coil arrays) dependencies between the two responses is observed in response to n=2 fields in the same plasma for which the n=1 responses are well synchronized.more » Neither the maximum radial nor the maximum poloidal field response to n=2 fields agrees with the best applied phasing for mitigating edge localized modes, suggesting that the edge plasma response is not a dominant component of either polarization. GPEC modeling reproduces the discrepant phasing dependences of the experimental measurements, and confirms the edge resonances are maximized by the coil phasing that mitigates ELMs in the experiments. The model confirms the measured plasma response is not dominated by resonant current drive from the external field. Instead, non-resonant contributions play a large role in the diagnostic signal for both toroidal harmonics n=1 and n=2. The analysis in this paper demonstrates the ability of 3D modeling to connect external magnetic sensor measurements to the internal plasma physics and accurately predict optimal applied 3D field configurations in multi-modal plasmas.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1249330-propagation-distance-resolved-characteristics-filament-induced-copper-plasma','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1249330-propagation-distance-resolved-characteristics-filament-induced-copper-plasma">Propagation distance-resolved characteristics of filament-induced copper plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a> Ghebregziabher, Isaac; Hartig, Kyle C.; Jovanovic, Igor 2016-03-02 Copper plasma generated at different filament-copper interaction points was characterized by spectroscopic, acoustic, and imaging measurements. The longitudinal variation of the filament intensity was qualitatively determined by acoustic measurements in air. The maximum plasma temperature was measured at the location of peak filament intensity, corresponding to the maximum mean electron energy during plasma formation. The highest copper plasma density was measured past the location of the maximum electron density in the filament, where spectral broadening of the filament leads to enhanced ionization. Acoustic measurements in air and on solid target were correlated to reconstructed plasma properties. Lastly, optimal line emissionmore » is measured near the geometric focus of the lens used to produce the filament.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/8593154','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/8593154">[Pharmacokinetics and effects of xylazine (Rompun) in dogs].</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Rector, E; Otto, K; Kietzmann, M; Nolte, I; Lehmacher, W 1996-01-01 Six beagle dogs were treated with xylazine hydrochloride (1 mg/kg i.m.). The plasma xylazine concentration was measured by HPLC. Additionally, clinical effects were registered (cardiac rate, respiratory activity, electrocardiogram, body temperature, motoric activity, attention, analgesia). Maximum plasma concentrations were measured after 15 minutes (476 ng/ml). The plasma half-life was 24 minutes. Sedation was registered over one hour (xylazine concentration of more than 150 ng/ml). Within the first 30 minutes after treatment (xylazine concentration of more than 300 ng/ml), a low-grade analgesia was observed. In contrast, cardiac and respiratoric depression and also significantly diminished body temperature were registered over 2 to 3 hours. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_1");'>1</a></li> <li><a href="#" onclick='return showDiv("page_2");'>2</a></li> <li class="active">3</li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_4" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_2");'>2</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li class="active">4</li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="61"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19850056896&hterms=runaway&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3Drunaway','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19850056896&hterms=runaway&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3Drunaway">Acceleration of runaway electrons and Joule heating in solar flares</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Holman, G. D. 1985-01-01 The electric field acceleration of electrons out of a thermal plasma and the simultaneous Joule heating of the plasma are studied. Acceleration and heating timescales are derived and compared, and upper limits are obtained on the acceleration volume and the rate at which electrons can be accelerated. These upper limits, determined by the maximum magnetic field strength observed in flaring regions, place stringent restrictions upon the acceleration process. The role of the plasma resistivity in these processes is examined, and possible sources of anomalous resistivity are summarized. The implications of these results for the microwave and hard X-ray emission from solar flares are examined. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19840017515','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19840017515">Acceleration of runaway electrons and Joule heating in solar flares</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Holman, G. D. 1984-01-01 The electric field acceleration of electrons out of a thermal plasma and the simultaneous Joule heating of the plasma are studied. Acceleration and heating timescales are derived and compared, and upper limits are obtained on the acceleration volume and the rate at which electrons can be accelerated. These upper limits, determined by the maximum magnetic field strength observed in flaring regions, place stringent restrictions upon the acceleration process. The role of the plasma resistivity in these processes is examined, and possible sources of anomalous resistivity are summarized. The implications of these results for the microwave and hard X-ray emission from solar flares are examined. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28986996','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28986996">Metabolite profiling of ginsenosides in rat plasma, urine and feces by LC-MS/MS and its application to a pharmacokinetic study after oral administration of Panax ginseng extract.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Dong, Wei-Wei; Han, Xiong-Zhe; Zhao, Jinhua; Zhong, Fei-Liang; Ma, Rui; Wu, Songquan; Li, Donghao; Quan, Lin-Hu; Jiang, Jun 2018-03-01 Panax ginseng is widely consumed as a functional food in the form of tea, powder, capsules, among others, and possesses a range of pharmacological activities including adaptogenic, immune-modulatory, anti-tumor, anti-aging and anti-inflammatory effects. The aim of this study was to identify and quantify the major ginsenosides and their metabolites in rat plasma, urine and feces after administration of P. ginseng extract using LC-MS/MS. We collected rat plasma samples at 0.5, 1, 2, 4, 8, 12, 24 and 48 h, and the amounts of urine and fecal samples accumulated in 24 h. Fourteen major ginsenosides and their metabolites were observed in fecal samples at high levels; however, low levels of 11 ginsenosides were detected in urine samples. The pharmacokinetics of the major ginsenosides and their metabolites was investigated in plasma. The results indicated that the maximum plasma concentration, time to maximum concentration and area under the curve of compound K were significantly greater than those of other ginsenosides. This study thus provides valuable information for drug development and clinical application of P. ginseng. Copyright © 2017 John Wiley & Sons, Ltd. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JGRA..123.3998Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JGRA..123.3998Y">Low-Latitude Ionospheric Density Irregularities and Associated Scintillations Investigated by Combining COSMIC RO and Ground-Based Global Positioning System Observations Over a Solar Active Period</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Yang, Zhe; Liu, Zhizhao 2018-05-01 This study for the first time presents a locally integrated analysis of occurrences of ionospheric E and F region irregularities/scintillations in southeast China, by employing radio occultation (RO) profile data retrieved from Constellation Observing System for Meteorology, Ionosphere, and Climate (COSMIC) satellites and observations from a ground-based Global Navigation Satellite System receiver over a solar active period from 2014 to 2015. Their occurrences in both nighttime and daytime were examined by using both amplitude scintillation index (S4) and the rate of change of total electron content index. It is found that (1) F region irregularities occurred predominantly during 20-03 local time (LT) and exhibited maximum (minimum) during equinoxes (solstices) and equinoctial (solstice) asymmetry. Their geographic mapping reveals the maximum occurrence in the westward tilted structure of equatorial plasma bubbles. In addition, the altitude-time variations indicate that their occurrences at higher altitudes were prevailing at 20-22 LT. (2) The E region irregularities were found prominently during 15-00 LT at altitudes of 90-110 km with an even geographic distribution. Their occurrences with maximum in summer (May-August) were distinctly detected by RO observations but insignificantly by ground-based observations. (3) By examining simultaneous observations of E and F region irregularities, it is found that they appeared absent during 21-00 LT and predominant after midnight. This could be related to the weakening/disruption of sporadic E (Es) layers during the development of equatorial plasma bubbles. A sign of coupling of E and F regions during nighttime is likely revealed from RO profile data. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011ApSS..257.2891B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011ApSS..257.2891B">Surface modification of argon/oxygen plasma treated vulcanized ethylene propylene diene polymethylene surfaces for improved adhesion with natural rubber</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Basak, Ganesh C.; Bandyopadhyay, Abhijit; Neogi, Sudarsan; Bhowmick, Anil K. 2011-01-01 Vulcanized ethylene propylene diene polymethylene (EPDM) rubber surface was treated in a radio frequency capacitatively coupled low pressure argon/oxygen plasma to improve adhesion with compounded natural rubber (NR) during co-vulcanization. The plasma modified surfaces were analyzed by means of contact angle measurement, surface energy, attenuated total reflection-infrared spectroscopy, X-ray photoelectron spectroscopy, scanning electron microscopy, energy dispersive X-ray sulfur mapping and atomic force microscopy. Several experimental variables such as plasma power, length of exposure time and composition of the argon-oxygen gas mixture were considered. It was delineated that plasma treatment changed both surface composition and roughness, and consequently increased peel strength. The change in surface composition was mainly ascribed to the formation of C-O and -Cdbnd O functional groups on the vulcanized surfaces. A maximum of 98% improvement in peel strength was observed after plasma treatment. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JPhD...50z5201T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JPhD...50z5201T">Frequency-tuning radiofrequency plasma source operated in inductively-coupled mode under a low magnetic field</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Takahashi, Kazunori; Nakano, Yudai; Ando, Akira 2017-07-01 A radiofrequency (rf) inductively-coupled plasma source is operated with a frequency-tuning impedance matching system, where the rf frequency is variable in the range of 20-50 MHz and the maximum power is 100 W. The source consists of a 45 mm-diameter pyrex glass tube wound by an rf antenna and a solenoid providing a magnetic field strength in the range of 0-200 Gauss. A reflected rf power for no plasma case is minimized at the frequency of ˜25 MHz, whereas the frequency giving the minimum reflection with the high density plasma is about 28 MHz, where the density jump is observed when minimizing the reflection. A high density argon plasma above 1× {{10}12} cm-3 is successfully obtained in the source for the rf power of 50-100 W, where it is observed that an external magnetic field of a few tens of Gauss yields the highest plasma density in the present configuration. The frequency-tuning plasma source is applied to a compact and high-speed silicon etcher in an Ar-SF6 plasma; then the etching rate of 8~μ m min-1 is obtained for no bias voltage to the silicon wafer, i.e. for the case that a physical ion etching process is eliminated. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19800016207&hterms=322&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D60%26Ntt%3Dp%2526%2523322','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19800016207&hterms=322&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D60%26Ntt%3Dp%2526%2523322">The needs for prediction and real-time monitoring for the flare build-up study</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Svestka, Z. 1979-01-01 Similarities between plasma instabilities occurring in the magnetospheric tail and in active regions on the Sun are discussed. Intense observations of the flare build-up processes on the Sun planned for May and June 1980 as a part of the Solar Maximum Year are described. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/4718066-some-new-data-self-compressed-discharges','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/4718066-some-new-data-self-compressed-discharges">SOME NEW DATA ON SELF-COMPRESSED DISCHARGES (in Russian)</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Kvartskhava, I.F.; Kervalidze, K.N.; Gvaladze, Yu.C. 1962-01-01 The theory of self-constricted discharges, which predicts the possibiiity of the appearance of various types of instabilities, does not reflect fully the multiple phenoniena which are experimentally observed. The models used in the theory evidentiy do not consider the presence of some processes in self- constricted discharges which materially determine the real behavior of the plasma. The experiments showed a number of such processes. Basically, they consist of an unequal heating of the discharge near the walls of the chamber. Thereby the discharge currents fiow along distorted threadlike channels which, in theta - pinches mostly follow either the z-direction ormore » the theta -direction, and in z- pinches they basically follow the theta -direction. In the process of plasma compression the above mentioned thread formations experience unequal accelerations. Having a high conductivity, these formations facilitate the capture of magnetic fieids which obstructs the thermaiization of the kinetic energy of the plasma's radial motion. As a result of this process the plasma is far from thermial equilibrium when in the stage of maximum compression. It is encompassed by a motion of turbulent character. After the maximum compression of the plasma, various kinds of plasma formation are ejected from the surface of the pinch. The magnetic field is more effectively trapped than in zpinches. Consequently, a greater variety of types of instability is observed in theta - pinches than in z-pinches. Highspeed photography of the discharge turned out to be the most practical and fruitful method of studying the processes of formation and the subsequent motion of the plasma. Photographs of the discharges obtained by streak photography and by framing camera are discussed. The results of probe measurements of magnetic and electric fields as well as the results of measurements of currents by means of Rogovsky belts are given. (auth)« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/17756006','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/17756006">First plasma wave observations at neptune.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Gurnett, D A; Kurth, W S; Poynter, R L; Granroth, L J; Cairns, I H; Macek, W M; Moses, S L; Coroniti, F V; Kennel, C F; Barbosa, D D 1989-12-15 The Voyager 2 plasma wave instrument detected many familiar plasma waves during the encounter with Neptune, including electron plasma oscillations in the solar wind upstream of the bow shock, electrostatic turbulence at the bow shock, and chorus, hiss, electron cyclotron waves, and upper hybrid resonance waves in the inner magnetosphere. Low-frequency radio emissions, believed to be generated by mode conversion from the upper hybrid resonance emissions, were also observed propagating outward in a disklike beam along the magnetic equatorial plane. At the two ring plane crossings many small micrometer-sized dust particles were detected striking the spacecraft. The maximum impact rates were about 280 impacts per second at the inbound ring plane crossing, and about 110 impacts per second at the outbound ring plane crossing. Most of the particles are concentrated in a dense disk, about 1000 kilometers thick, centered on the equatorial plane. However, a broader, more tenuous distribution also extends many tens of thousands of kilometers from the equatorial plane, including over the northern polar region. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19850025584','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19850025584">Simultaneous Solar Maximum Mission and Very Large Array (VLA) observations of solar active regions</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Lang, K. R. 1985-01-01 Simultaneous observations of solar active regions with the Solar Maximum Mission (SMM) Satellite and the Very Large Array (VLA) have been obtained and analyzed. Combined results enhance the scientific return for beyond that expeted from using either SMM or VLA alone. A total of two weeks of simultaneous SMM/VLA data were obtained. The multiple wavelength VLA observations were used to determine the temperature and magnetic structure at different heights within coronal loops. These data are compared with simultaneous SMM observations. Several papers on the subject are in progress. They include VLA observations of compact, transient sources in the transition region; simultaneous SMM/VLA observations of the coronal loops in one active region and the evolution of another one; and sampling of the coronal plasma using thermal cyclotron lines (magnetic field - VLA) and soft X ray spectral lines (electron density and electron temperaure-SMM). </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/20110007807','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20110007807">Constraints on CME Evolution from in situ Observations of Ionic Charge States</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Gruesbeck, Jacob R.; Lepri, Susan T.; Zurbuchen, Thomas H.; Antiochos, Spiro K. 2010-01-01 We present a novel procedure for deriving the physical properties of Coronal Mass Ejections (CMES) in the corona. Our methodology uses in-situ measurements of ionic charge states of C, O, Si and Fe in the heliosphere and interprets them in the context of a model for the early evolution of ICME plasma, between 2 - 5 R-solar. We find that the data can be fit only by an evolution that consists of an initial heating of the plasma, followed by an expansion that ultimately results in cooling. The heating profile is consistent with a compression of coronal plasma due to flare reconnect ion jets and an expansion cooling due to the ejection, as expected from the standard CME/flare model. The observed frozen-in ionic charge states reflect this time-history and, therefore, provide important constraints for the heating and expansion time-scales, as well as the maximum temperature the CME plasma is heated to during its eruption. Furthermore, our analysis places severe limits on the possible density of CME plasma in the corona. We discuss the implications of our results for CME models and for future analysis of ICME plasma composition. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22493793-oblique-collision-dust-acoustic-solitons-strongly-coupled-dusty-plasma','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22493793-oblique-collision-dust-acoustic-solitons-strongly-coupled-dusty-plasma">Oblique collision of dust acoustic solitons in a strongly coupled dusty plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Boruah, A.; Sharma, S. K., E-mail: sumita-sharma82@yahoo.com; Bailung, H. 2015-09-15 The oblique collision between two equal amplitude dust acoustic solitons is observed in a strongly coupled dusty plasma. The solitons are subjected to oblique interaction at different colliding angles. We observe a resonance structure during oblique collision at a critical colliding angle which is described by the idea of three wave resonance interaction modeled by Kadomtsev-Petviashvili equation. After collision, the solitons preserve their identity. The amplitude of the resultant wave formed during interaction is measured for different collision angles as well as for different colliding soliton amplitudes. At resonance, the maximum amplitude of the new soliton formed is nearly 3.7more » times the initial soliton amplitude.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20110022963&hterms=taylor&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAuthor-Name%26N%3D0%26No%3D20%26Ntt%3Dtaylor%2Bt%2Bb','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20110022963&hterms=taylor&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAuthor-Name%26N%3D0%26No%3D20%26Ntt%3Dtaylor%2Bt%2Bb">Extended Magnetic Reconnection Across the Dayside Magnetopause</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Dunlop, M. W.; Zhang, Q.-H.; Bogdanova, Y. V.; Lockwood, M.; Pu, Z.; Hasegawa, H.; Wang, J.; Taylor, M. G. G. T.; Berchem, J.; Lavraund, B.; <a style="text-decoration: none; " href="javascript:void(0); " onClick="displayelement('author_20110022963'); toggleEditAbsImage('author_20110022963_show'); toggleEditAbsImage('author_20110022963_hide'); "> <img style="display:inline; width:12px; height:12px; " src="images/arrow-up.gif" width="12" height="12" border="0" alt="hide" id="author_20110022963_show"> <img style="width:12px; height:12px; display:none; " src="images/arrow-down.gif" width="12" height="12" border="0" alt="hide" id="author_20110022963_hide"> 2011-01-01 The extent of where magnetic reconnection (MR), the dominant process responsible for energy and plasma transport into the magnetosphere, operates across Earth's dayside magnetopause has previously been only indirectly shown by observations. We report the first direct evidence of X-line structure resulting from the operation of MR at each of two widely separated locations along the tilted, subsolar line of maximum current on Earth's magnetopause, confirming the operation of MR at two or more sites across the extended region where MR is expected to occur. The evidence results from in-situ observations of the associated ion and electron plasma distributions, present within each magnetic X-line structure, taken by two spacecraft passing through the active MR regions simultaneously. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5465324','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5465324">Lack of effect of oral cabotegravir on the pharmacokinetics of a levonorgestrel/ethinyl oestradiol‐containing oral contraceptive in healthy adult women</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Trezza, Christine; Ford, Susan L.; Gould, Elizabeth; Lou, Yu; Huang, Chuyun; Ritter, James M.; Buchanan, Ann M.; Spreen, William 2017-01-01 Aims This study aimed to investigate whether cabotegravir (CAB), an integrase inhibitor in development for treatment and prevention of human immunodeficiency virus‐1, influences the pharmacokinetics (PK) of a levonorgestrel (LNG) and ethinyl oestradiol (EO)–containing oral contraceptive (OC) in healthy women. Methods In this open‐label, fixed‐sequence crossover study, healthy female subjects received LNG 0.15 mg/EO 0.03 mg tablet once daily Days 1–10 alone and with oral CAB 30 mg once daily Days 11–21. At the end of each treatment period, subjects underwent predose sampling for concentrations of follicle‐stimulating hormone, luteinizing hormone, and progesterone and serial PK sampling for plasma LNG, EO, and CAB concentrations. Results Twenty women were enrolled, and 19 completed the study. One subject was withdrawn due to an adverse event unrelated to study medications. Geometric least squares mean ratios (90% confidence interval) of LNG + CAB vs. LNG alone for LNG area under the plasma concentration–time curve over the dosing interval of duration τ and maximum observed plasma concentration were 1.12 (1.07–1.18) and 1.05 (0.96–1.15), respectively. Geometric least squares mean ratio (90% confidence interval) of EO + CAB vs. EO alone for EO area under the plasma concentration–time curve over the dosing interval of duration τ and maximum observed plasma concentration were 1.02 (0.97–1.08) and 0.92 (0.83–1.03), respectively. Steady‐state CAB PK parameters were comparable to historical values. There was no apparent difference in mean luteinizing hormone, follicle‐stimulating hormone, and progesterone concentrations between periods. No clinically significant trends in laboratory values, vital signs, or electrocardiography values were observed. Conclusions Repeat doses of oral CAB had no significant effect on LNG/EO PK or pharmacodynamics, which supports CAB coadministration with LNG/EO OCs in clinical practice. PMID:28087972 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2008R%26QE...51..858T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2008R%26QE...51..858T">First observations of stimulated electromagnetic emission in the ionosphere modified by the spear heating facility on Spitsbergen</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Tereshchenko, E. D.; Yurik, R. Yu.; Yeoman, T. K.; Robinson, T. R. 2008-11-01 We present the first results of observations of the stimulated electromagnetic emission (SEE) in the ionosphere modified by the Space Plasma Exploration by Active Radar (SPEAR) heating facility. Observation of the SEE is the key method of ground-based diagnostics of the ionospheric plasma disturbances due to high-power HF radiation. The presented results were obtained during the heating campaign performed at the SPEAR facility in February-March 2007. Prominent SEE special features were observed in periods in which the critical frequency of the F 2 layer was higher than the pump-wave frequency (4.45 MHz). As an example, such special features as the downshifted maximum and the broad continuum in the region of negative detunings from the pump-wave frequency are presented. Observations clearly demonstrate that the ionosphere was efficiently excited by the SPEAR heating facility despite the comparatively low pump-wave power. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017RaSc...52..951S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017RaSc...52..951S">Evaluation of extreme ionospheric total electron content gradient associated with plasma bubbles for GNSS Ground-Based Augmentation System</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Saito, S.; Yoshihara, T. 2017-08-01 Associated with plasma bubbles, extreme spatial gradients in ionospheric total electron content (TEC) were observed on 8 April 2008 at Ishigaki (24.3°N, 124.2°E, +19.6° magnetic latitude), Japan. The largest gradient was 3.38 TECU km-1 (total electron content unit, 1 TECU = 1016 el m-2), which is equivalent to an ionospheric delay gradient of 540 mm km-1 at the GPS L1 frequency (1.57542 GHz). This value is confirmed by using multiple estimating methods. The observed value exceeds the maximum ionospheric gradient that has ever been observed (412 mm km-1 or 2.59 TECU km-1) to be associated with a severe magnetic storm. It also exceeds the assumed maximum value (500 mm km-1 or 3.08 TECU km-1) which was used to validate the draft international standard for Global Navigation Satellite System (GNSS) Ground-Based Augmentation Systems (GBAS) to support Category II/III approaches and landings. The steepest part of this extreme gradient had a scale size of 5.3 km, and the front-normal velocities were estimated to be 71 m s-1 with a wavefront-normal direction of east-northeastward. The total width of the transition region from outside to inside the plasma bubble was estimated to be 35.3 km. The gradient of relatively small spatial scale size may fall between an aircraft and a GBAS ground subsystem and may be undetectable by both aircraft and ground. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1999AAS...194.8003A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1999AAS...194.8003A">YOHKOH Observations at the Y2K Solar Maximum</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Aschwanden, M. J. 1999-05-01 Yohkoh will provide simultaneous co-aligned soft X-ray and hard X-ray observations of solar flares at the coming solar maximum. The Yohkoh Soft X-ray Telescope (SXT) covers the approximate temperature range of 2-20 MK with a pixel size of 2.46\\arcsec, and thus complements ideally the EUV imagers sensitive in the 1-2 MK plasma, such as SoHO/EIT and TRACE. The Yohkoh Hard X-ray Telescope (HXT) offers hard X-ray imaging at 20-100 keV at a time resolution of down to 0.5 sec for major events. In this paper we review the major SXT and HXT results from Yohkoh solar flare observations, and anticipate some of the key questions that can be addressed through joint observations with other ground and space-based observatories. This encompasses the dynamics of flare triggers (e.g. emerging flux, photospheric shear, interaction of flare loops in quadrupolar geometries, large-scale magnetic reconfigurations, eruption of twisted sigmoid structures, coronal mass ejections), the physics of particle dynamics during flares (acceleration processes, particle propagation, trapping, and precipitation), and flare plasma heating processes (chromospheric evaporation, coronal energy loss by nonthermal particles). In particular we will emphasize on how Yohkoh data analysis is progressing from a qualitative to a more quantitative science, employing 3-dimensional modeling and numerical simulations. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018NucFu..58g6016L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018NucFu..58g6016L">Magnetic polarization measurements of the multi-modal plasma response to 3D fields in the EAST tokamak</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Logan, N. C.; Cui, L.; Wang, H.; Sun, Y.; Gu, S.; Li, G.; Nazikian, R.; Paz-Soldan, C. 2018-07-01 A multi-modal plasma response to applied non-axisymmetric fields has been found in EAST tokamak plasmas. Here, multi-modal means the radial and poloidal structure of an individually driven toroidal harmonic is not fixed. The signature of such a multi-modal response is the magnetic polarization (ratio of radial and poloidal components) of the plasma response field measured on the low field side device mid-plane. A difference in the 3D coil phasing (the relative phase of two coil arrays) dependencies between the two responses is observed in response to n = 2 fields in the same plasma for which the n = 1 responses are well synchronized. Neither the maximum radial nor the maximum poloidal field response to n = 2 fields agrees with the best applied phasing for mitigating edge localized modes, suggesting that the edge plasma response is not a dominant component of either polarization. GPEC modeling reproduces the discrepant phasing dependences of the experimental measurements, and confirms the edge resonances are maximized by the coil phasing that mitigates ELMs in the experiments. The model confirms the measured plasma response is not dominated by resonant current drive from the external field. Instead, non-resonant contributions play a large role in the diagnostic signal for both toroidal harmonics n = 1 and n = 2. The analysis in this paper demonstrates the ability of 3D modeling to connect external magnetic sensor measurements to the internal plasma physics and accurately predict optimal applied 3D field configurations in multi-modal plasmas. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20691128','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20691128">Plasma appearance and correlation between coffee and green tea metabolites in human subjects.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Renouf, Mathieu; Guy, Philippe; Marmet, Cynthia; Longet, Karin; Fraering, Anne-Lise; Moulin, Julie; Barron, Denis; Dionisi, Fabiola; Cavin, Christophe; Steiling, Heike; Williamson, Gary 2010-12-01 Coffee and green tea are two of the most widely consumed hot beverages in the world. Their respective bioavailability has been studied separately, but absorption of their respective bioactive phenolics has not been compared. In a randomised cross-over design, nine healthy subjects drank instant coffee and green tea. Blood samples were collected over 12 h and at 24 h to assess return to baseline. After green tea consumption, (-)-epigallocatechin (EGC) was the major catechin, appearing rapidly in the plasma; (-)-EGC gallate (EGCg) and (-)-epicatechin (EC) were also present, but (-)-EC gallate and C were not detected. Dihydroferulic acid and dihydrocaffeic acid were the major metabolites that appeared after coffee consumption with a long time needed to reach maximum plasma concentration, suggesting metabolism and absorption in the colon. Other phenolic acid equivalents (caffeic acid (CA), ferulic acid (FA) and isoferulic acid (iFA)) were detected earlier, and they peaked at lower concentrations. Summations of the plasma area under the curves (AUC) for the measured metabolites showed 1.7-fold more coffee-derived phenolic acids than green tea-derived catechins (P = 0.0014). Furthermore, we found a significant correlation between coffee metabolites based on AUC. Inter-individual differences were observed, but individuals with a high level of CA also showed a correspondingly high level of FA. However, no such correlation was observed between the tea catechins and coffee phenolic acids. Correlation between AUC and maximum plasma concentration was also significant for CA, FA and iFA and for EGCg. This implies that the mechanisms of absorption for these two classes of compounds are different, and that a high absorber of phenolic acids is not necessarily a high absorber of catechins. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018ApPhA.124...59I','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018ApPhA.124...59I">Plasma-treated Langmuir-Blodgett reduced graphene oxide thin film for applications in biophotovoltaics</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Ibrahim, Siti Aisyah; Jaafar, Muhammad Musoddiq; Ng, Fong-Lee; Phang, Siew-Moi; Kumar, G. Ghana; Majid, Wan Haliza Abd; Periasamy, Vengadesh 2018-01-01 The surface optimization and structural characteristics of Langmuir-Blodgett (LB) reduced graphene oxide thin (rGO) film treated by argon plasma treatment were studied. In this work, six times deposition of rGO was deposited on a clean glass substrate using the LB method. Plasma technique involving a variation of plasma power, i.e., 20, 60, 100 and 140 W was exposed to the LB-rGO thin films under argon ambience. The plasma treatment generally improves the wettability or hydrophilicity of the film surface compared to without treatment. Maximum wettability was observed at a plasma power of 20 W, while also increasing the adhesion of the rGO film with the glass substrate. The multilayer films fabricated were characterized by means of spectroscopic, structural and electrical studies. The treatment of rGO with argon plasma was found to have improved its biocompatibility, and thus its performance as an electrode for biophotovoltaic devices has been shown to be enhanced considerably. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_2");'>2</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li class="active">4</li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_5" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li class="active">5</li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="81"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22162970-boltzmann-expansion-radiofrequency-conical-helicon-thruster-operating-xenon-argon','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22162970-boltzmann-expansion-radiofrequency-conical-helicon-thruster-operating-xenon-argon">Boltzmann expansion in a radiofrequency conical helicon thruster operating in xenon and argon</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Charles, C.; Boswell, R.; Takahashi, K. 2013-06-03 A low pressure ({approx}0.5 mTorr in xenon and {approx}1 mTorr in argon) Boltzmann expansion is experimentally observed on axis within a magnetized (60 to 180 G) radiofrequency (13.56 MHz) conical helicon thruster for input powers up to 900 W using plasma parameters measured with a Langmuir probe. The axial forces, respectively, resulting from the electron and magnetic field pressures are directly measured using a thrust balance for constant maximum plasma pressure and show a higher fuel efficiency for argon compared to xenon. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/11402958','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/11402958">Effects in vivo of iohexol and diatrizoate on human plasma acetyl- and butyryl-cholinesterase activity.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Mironidou, M; Katsimba, D; Kokkas, B; Kaitartzis, C; Karamanos, G; Christopoulos, S 2001-03-01 The aim of this study was to evaluate the effects of two iodinate contrast agents (CA), iohexol and diatrizoate, on human plasma acetyl-(AC) and butyrylcholinesterase(BC) activity. Forty-eight patients (24 males and 24 females) scheduled for intravenous pyelography were randomly divided into four groups of 6 males and 6 females each, receiving as CA, respectively: iohexol (Omnipaque, Schering) 0.6 ml/kg body weight (G1); iohexol 1.2 mg/kg (G2); sodium and meglumine diatrizoate 58% (Urografin, Schering) 0.6 ml/kg (G3); sodium and meglumine diatrizoate 58% 1.2 ml/kg (G4). Blood samples were taken before and 5, 10, and 20 min after the injection. Enzymatic activity of AC and BC were measured by spectrophotometry. Plasma concentration of K, Na, Ca, and Mg was measured in all blood samples; blood pressure and plasma pH were measured after each sample collection. Statistical analysis was performed by Student's test. In G1 a reversible decrease of AC (12.9%) and BC (8.2%) plasma activity was observed at 10 min. In G2 a progressive decrease of AC (13.9%) and BC (18.4%) plasma activity was observed with a maximum at 20 min. In G3 a modest reversible decrease of BC plasma activity (5.4%) was observed. In G4 a modest progressive decrease of AC (7.3%) and BC (6.5%) plasma activities was observed. In all cases, AC and BC plasma activities remained within the normal range of values. Plasma concentration of K, Na, Ca, and Mg, as well as pH and systolic and diastolic pressure, did not show any change. No adverse effects was observed in our patients. Iohexol and diatrizoate induce in vivo a significant decrease of AC and BC plasma activities. The decrease is more pronounced for iohexol, a non ionic CA, which has a lower pharmacotoxicity than diatrizoate and adverse effects rate. No inference can be drawn about the relationship between plasma cholinesterase activity and adverse effects. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018AIPC.1942e0108G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018AIPC.1942e0108G">Oxidation behaviour of Fe-Ni alloy nanoparticles synthesized by thermal plasma route</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Ghodke, Neha; Kamble, Shalaka; Raut, Suyog; Puranik, Shridhar; Bhoraskar, S. V.; Rayaprol, Sudhindra; Mathe, V. L. 2018-04-01 Here we report synthesis of Fe-Ni nanoparticles using thermal plasma route. In thermal plasma, gas phase nucleation and growth at sufficiently higher temperature is observed. The synthesized Fe-Ni nanoparticles are examined by X-ray Diffraction, Raman Spectroscopy, Vibrating Sample Magnetometer and Thermo gravimetric Analysis. Formation of 16-21 nm sized Fe-Ni nanoparticles having surface oxidation show maximum value of magnetization of ˜107 emu/g. The sample synthesized at relatively low power (4kW) show presence of carbonaceous species whereas the high power (6 kW) synthesis does not depicts carbonaceous species. The presence of carbonaceous species protects oxidation of the nanoparticles significantly as evidenced from TGA data. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA133975','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA133975">Electrostatic Ion-Cyclotron Waves in Magnetospheric Plasmas: Non-Local Aspects.</a> <a target="_blank" rel="noopener noreferrer" href="http://www.dtic.mil/">DTIC Science & Technology</a> 1983-10-14 moving observer will see a Doppler shifted frequency --- S where is the velocity vector of the observer (satellite) and k is the wave vector. Since k...direction) will not see any Doppler -shift, irrespective of the size of ky . Such a statement could not be made in the purely local theory, since there...a local theory, a wide range of Doppler shifts would be produced, from -kivs to +kivs, since the maximum value of kx is k1. Some of the observations </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4745916','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4745916">Relationship between Sustained Reductions in Plasma Lipid and Lipoprotein Concentrations with Apheresis and Plasma Levels and mRNA Expression of PTX3 and Plasma Levels of hsCRP in Patients with HyperLp(a)lipoproteinemia</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Stefanutti, Claudia; Mazza, Fabio; Steiner, Michael; Watts, Gerald F.; De Nève, Joel; Pasqualetti, Daniela; Paal, Juergen 2016-01-01 The effect of lipoprotein apheresis (Direct Adsorption of Lipids, DALI) (LA) on plasma levels of pentraxin 3 (PTX3), an inflammatory marker that reflects coronary plaque vulnerability, and expression of PTX3 mRNA was evaluated in patients with hyperLp(a)lipoproteinemia and angiographically defined atherosclerosis/coronary artery disease. Eleven patients, aged 55 ± 9.3 years (mean ± SD), were enrolled in the study. PTX3 soluble protein levels in plasma were unchanged by 2 sessions of LA; however, a downregulation of mRNA expression for PTX3 was observed, starting with the first session of LA (p < 0.001). The observed reduction was progressively increased in the interval between the first and second LA sessions to achieve a maximum decrease by the end of the second session. A statistically significantly greater treatment-effect correlation was observed in patients undergoing weekly treatments, compared with those undergoing treatment every 15 days. A progressive reduction in plasma levels of C-reactive protein was also seen from the first session of LA, with a statistically significant linear correlation for treatment-effect in the change in plasma levels of this established inflammatory marker (R 2 = 0.99; p < 0.001). Our findings suggest that LA has anti-inflammatory and endothelium protective effects beyond its well-established efficacy in lowering apoB100-containing lipoproteins. PMID:26903710 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1373691-ag+-reduction-silver-nanoparticle-synthesis-plasmaliquid-interface-rf-driven-atmospheric-pressure-plasma-jet-mechanisms-effect-surfactant','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1373691-ag+-reduction-silver-nanoparticle-synthesis-plasmaliquid-interface-rf-driven-atmospheric-pressure-plasma-jet-mechanisms-effect-surfactant">Ag + reduction and silver nanoparticle synthesis at the plasma–liquid interface by an RF driven atmospheric pressure plasma jet: Mechanisms and the effect of surfactant</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a> Kondeti, V. S. Santosh K.; Gangal, Urvashi; Yatom, Shurik; ... 2017-07-21 Here, the involvement of plasma produced species in the reduction of silver ions at the plasma–liquid interface is investigated using a well-characterized radio-frequency driven atmospheric pressure plasma jet. The absolute gas phase H density was measured using two photon absorption laser induced fluorescence in the free jet. Broadband absorption and transmission electron microscopy were used to study the synthesis of silver nanoparticles (AgNPs). It is shown that fructose, an often used surfactant/stabilizer for AgNP synthesis, also acts as a reducing agent after plasma exposure. Nonetheless, surfactant free AgNP synthesis is observed. Several experimental findings indicate that H plays an importantmore » role in the reduction of silver ions for the plasma conditions in this study. Vacuum ultraviolet photons generated by the plasma are able to reduce silver ions in the presence of fructose. Adding H2 to the argon feed gas leads to the production of a large amount of AgNPs having a particle size distribution with a maximum at a diameter of 2–3 nm, which is not observed for argon plasmas. This finding is consistent with a smaller concentration of reducing species at the plasma–liquid interface for Ar with the H2 admixture plasma. The smaller flux of reactive species to the liquid is in this case due to a less strong interaction of the plasma with the liquid. The formation of the nanoparticles was observed even at a distance of 6–7 mm below the tip of the plasma plume, conditions not favoring the injection of electrons.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/1373691-ag+-reduction-silver-nanoparticle-synthesis-plasmaliquid-interface-rf-driven-atmospheric-pressure-plasma-jet-mechanisms-effect-surfactant','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/1373691-ag+-reduction-silver-nanoparticle-synthesis-plasmaliquid-interface-rf-driven-atmospheric-pressure-plasma-jet-mechanisms-effect-surfactant">Ag + reduction and silver nanoparticle synthesis at the plasma–liquid interface by an RF driven atmospheric pressure plasma jet: Mechanisms and the effect of surfactant</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Kondeti, V. S. Santosh K.; Gangal, Urvashi; Yatom, Shurik Here, the involvement of plasma produced species in the reduction of silver ions at the plasma–liquid interface is investigated using a well-characterized radio-frequency driven atmospheric pressure plasma jet. The absolute gas phase H density was measured using two photon absorption laser induced fluorescence in the free jet. Broadband absorption and transmission electron microscopy were used to study the synthesis of silver nanoparticles (AgNPs). It is shown that fructose, an often used surfactant/stabilizer for AgNP synthesis, also acts as a reducing agent after plasma exposure. Nonetheless, surfactant free AgNP synthesis is observed. Several experimental findings indicate that H plays an importantmore » role in the reduction of silver ions for the plasma conditions in this study. Vacuum ultraviolet photons generated by the plasma are able to reduce silver ions in the presence of fructose. Adding H2 to the argon feed gas leads to the production of a large amount of AgNPs having a particle size distribution with a maximum at a diameter of 2–3 nm, which is not observed for argon plasmas. This finding is consistent with a smaller concentration of reducing species at the plasma–liquid interface for Ar with the H2 admixture plasma. The smaller flux of reactive species to the liquid is in this case due to a less strong interaction of the plasma with the liquid. The formation of the nanoparticles was observed even at a distance of 6–7 mm below the tip of the plasma plume, conditions not favoring the injection of electrons.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15379016','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15379016">High-speed photography of plasma during excimer laser-tissue interaction.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Murray, Andrea K; Dickinson, Mark R 2004-08-07 During high fluence laser-tissue interaction, ablation of tissue occurs, debris is removed from the ablation site and is then ejected at high velocity. This debris may be observed as a combination of luminous plasma and non-luminous plume, both of which have the potential to shield the ablation site. This study examined the role of ablation debris in shielding the tissue and determined its effects on the ablation rate over a range of laser pulse energies, pulse repetition rates and pulse numbers for dentine; the velocity differences between hard and soft tissues were also examined. High-speed photography was carried out at up to 1 x 10(8) frames per second. A maximum velocity of 2.58 +/- 0.52 x 10(4) m s(-1) was recorded for dentine debris within the first 10 ns following ejection. The maximum duration of tissue shielding due to a single pulse, determined by attenuation of a probe beam, was found to be approximately 7 ms, approximately 80 micros of which was due to luminous plasma and the remainder due to the non-luminous plume. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016APS..DPPCO8013S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016APS..DPPCO8013S">The Effect of Driver Rise-Time on Pinch Current and its Impact on Plasma Focus Performance and Neutron Yield</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Sears, Jason; Schmidt, Andrea; Link, Anthony; Welch, Dale 2016-10-01 Experiments have suggested that dense plasma focus (DPF) neutron yield increases with faster drivers [Decker NIMP 1986]. Using the particle-in-cell code LSP [Schmidt PRL 2012], we reproduce this trend in a kJ DPF [Ellsworth 2014], and demonstrate how driver rise time is coupled to neutron output. We implement a 2-D model of the plasma focus including self-consistent circuit-driven boundary conditions. Driver capacitance and voltage are varied to modify the current rise time, and anode length is adjusted so that run-in coincides with the peak current. We observe during run down that magnetohydrodynamic (MHD) instabilities of the sheath shed blobs of plasma that remain in the inter-electrode gap during run in. This trailing plasma later acts as a low-inductance restrike path that shunts current from the pinch during maximum compression. While the MHD growth rate increases slightly with driver speed, the shorter anode of the fast driver allows fewer e-foldings and hence reduces the trailing mass between electrodes. As a result, the fast driver postpones parasitic restrikes and maintains peak current through the pinch during maximum compression. The fast driver pinch therefore achieves best simultaneity between its ion beam and peak target density, which maximizes neutron production. Prepared by LLNL under Contract DE-AC52-07NA27344. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20040082225&hterms=Gradient&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D80%26Ntt%3DGradient','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20040082225&hterms=Gradient&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D80%26Ntt%3DGradient">Pickup Ion Velocity Distributions at Titan: Effects of Spatial Gradients</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Hartle, R. E.; Sittler, E. C. 2004-01-01 The principle source of pickup ions at Titan is its neutral exosphere, extending well above the ionopause into the magnetosphere of Saturn or the solar wind, depending on the moon's orbital position. Thermal and nonthermal processes in the thermosphere generate the distribution of neutral atoms and molecules in the exosphere. The combination of these processes and the range of mass numbers, 1 to over 28, contribute to an exospheric source structure that produces pickup ions with gyroradii that are much larger or smaller than the corresponding scale heights of their neutral sources. The resulting phase space distributions are dependent on the spatial structure of the exosphere as well as that of the magnetic field and background plasma. When the pickup ion gyroradius is less than the source gas scale height, the pickup ion velocity distribution is characterized by a sharp cutoff near the maximum speed, which is twice that of the ambient plasma times the sine of the angle between the magnetic field and the flow velocity. This was the case for pickup H(sup +) ions identified during the Voyager 1 flyby. In contrast, as the gyroradius becomes much larger than the scale height, the peak of the velocity distribution in the source region recedes from the maximum speed. Iri addition, the amplitude of the distribution near the maximum speed decreases. These more beam like distributions of heavy ions were not observed from Voyager 1 , but should be observable by more sensitive instruments on future spacecraft, including Cassini. The finite gyroradius effects in the pickup ion velocity distributions are studied by including in the analysis the possible range of spatial structures in the neutral exosphere and background plasma. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013AGUFMSA43C..07C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013AGUFMSA43C..07C">The Mesoscale Ionospheric Simulation Testbed (MIST) Regional Data Assimilation Model (Invited)</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Comberiate, J.; Kelly, M. A.; Miller, E.; Paxton, L. 2013-12-01 The Mesoscale Ionospheric Simulation Testbed (MIST) provides a regional nowcast and forecast of electron density values and has sufficient resolution to include equatorial plasma bubbles. The SSUSI instrument on the DMSP F18 satellite has high-resolution nightly observations of plasma bubbles at 8 PM local time throughout the current solar maximum. MIST can assimilate SSUSI UV observations, GPS TEC measurements, and SCINDA S4 readings simultaneously into a single scintillation map over a region of interest. MIST also models ionospheric physics to provide a short-term UHF scintillation forecast based on assimilated data. We will present examples of electron density and scintillation maps from MIST. We will also discuss the potential to predict scintillation occurrence up to 6 hours in advance using observations of the equatorial arcs from SSUSI observations at 5:30 PM local time on the DMSP F17 satellite. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/17923446','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/17923446">Sensitive and rapid liquid chromatography/tandem mass spectrometric assay for the quantification of piperaquine in human plasma.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Singhal, Puran; Gaur, Ashwani; Gautam, Anirudh; Varshney, Brijesh; Paliwal, Jyoti; Batra, Vijay 2007-11-01 A simple, sensitive and rapid liquid chromatography/tandem mass spectrometric (LC-MS/MS) method was developed and validated for quantification of piperaquine, an antimalarial drug, in human plasma using its structural analogue, piperazine bis chloroquinoline as internal standard (IS). The method involved a simple protein precipitation with methanol followed by rapid isocratic elution of analytes with 10mM ammonium acetate buffer/methanol/formic acid/ammonia solution (25/75/0.2/0.15, v/v) on Chromolith SpeedROD RP-18e reversed phase chromatographic column and quantification by mass spectrometry in the multiple reaction monitoring mode (MRM). The precursor to product ion transitions of m/z 535.3-->288.2 and m/z 409.1-->205.2 were used to measure the analyte and the IS, respectively. The assay exhibited a linear dynamic range of 1.0-250.2 ng/mL for piperaquine in plasma. The limit of detection (LOD) and lower limit of quantification (LLOQ) in plasma were 0.2 and 1.0 ng/mL, respectively. Acceptable precision and accuracy (+/-20% deviation for LLOQ standard and +/-15% deviation for other standards from the respective nominal concentration) were obtained for concentrations over the standard curve ranges. A run time of 2.5 min for a sample made it possible to achieve a throughput of more than 400 plasma samples analyzed per day. The validated method was successfully applied to analyze human plasma samples from phase-1 clinical studies. The mean pharmacokinetic parameters of piperaquine following 1000 mg oral dose: observed maximum plasma concentration (Cmax), time to maximum plasma concentration (Tmax) and elimination half-life (T1/2) were 46.1 ng/mL, 3.8h and 13 days, respectively. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017Ge%26Ae..57..916T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017Ge%26Ae..57..916T">Flare Plasma Diagnostics from X-Ray and Ultraviolet Observations</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Tsap, Yu. T.; Motorina, G. G. 2017-12-01 We compare the measured values of emission measure EM and temperature T of coronal flare plasma following the GOES, RHESSI, and SDO/AIA satellite observations for the events of July 4, 5, and 7, 2012, in the NOAA 11515 active region. We show that the values of EM and T can vary widely (up to one order of magnitude for EM) depending on the technical features of instruments and processing technique. The maximum difference has been found to be between RHESSI and SDO/AIA measurements for temperature and between GOES and SDO/AIA measurements for EM. We discuss the pros and cons of the approaches used and the practical effects of the resulting numerical estimates for EM and T. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/6851137','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/6851137">Stereospecificity of phenylalanine plasma kinetics and hydroxylation in man following oral application of a stable isotope-labelled pseudo-racemic mixture of L- and D-phenylalanine.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Lehmann, W D; Theobald, N; Fischer, R; Heinrich, H C 1983-03-14 L-[15N]Phenylalanine and D-[2H5]phenylalanine have been administered orally to two healthy adult volunteers as a pseudo-racemic mixture at a dose of 25 mg/kg each. After oral application, the plasma kinetics of phenylalanine and tyrosine have been followed by the combined use of high pressure liquid chromatography and field desorption mass spectrometry. Additional incubation with D-amino acid oxidase was used to determine the enantiomeric composition of the differently labelled species of phenylalanine and tyrosine. D-Phenylalanine plasma levels show a faster rise to higher maximum values compared to L-phenylalanine (D/L ratio at maximum 3.19, 3.26). L-Phenylalanine is efficiently hydroxylated to L-tyrosine. In contrast, conversion of D-phenylalanine to the L-form with subsequent hydroxylation to L-tyrosine was observed. From the plasma kinetics it is estimated that about 1/3 of the applied dose of 25 mg/kg of D-phenylalanine is converted to the L-isomer. Of the administered dose of L-phenylalanine only very small amounts are excreted into urine as such (0.25%, 0.8%), whereas a substantial amount of the D-phenylalanine dose is found in urine (27.4%, 38.0%). </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017SPIE10240E..17B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017SPIE10240E..17B">Concerted manipulation of laser plasma dynamics with two laser pulses</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Braenzel, J.; Andreev, A. A.; Ehrentraut, L.; Sommer, D.; Schnürer, M. 2017-05-01 In this article we present experimental results from a counter-propagating two laser pulse experiment at high intensity and using ultrathin gold and plastic foil targets. We applied one laser pulse as a pre-pulse with an intensity of up to 1x1018 W/cm2. By this method we manipulated the pre-plasma of the foil target with which the stronger laser pulse with an intensity of 6x1019W/cm2 interacts. This alters significantly subsequent processes from the laser plasma interaction which we show the ion acceleration and high harmonic generation. On the one hand, the maximum kinetic ion energy and the maximum charge state for gold ions decline due to the pre-heating of the target in the time range of few ps, on the other hand the number of accelerated ions is increased. For the same parameter range we detected a significant raise of the high harmonic emission. Moreover, we present first experimental observations, that when the second laser pulse is applied as a counter-propagating post-pulse the energy distribution of accelerated carbon ions is charge selective altered. Our findings indicate that using this method a parametric optimization can be achieved, which promises new insights about the concurrent processes of the laser plasma dynamics. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2007JAP...102k3301L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2007JAP...102k3301L">Electron acceleration by surface plasma waves in double metal surface structure</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Liu, C. S.; Kumar, Gagan; Singh, D. B.; Tripathi, V. K. 2007-12-01 Two parallel metal sheets, separated by a vacuum region, support a surface plasma wave whose amplitude is maximum on the two parallel interfaces and minimum in the middle. This mode can be excited by a laser using a glass prism. An electron beam launched into the middle region experiences a longitudinal ponderomotive force due to the surface plasma wave and gets accelerated to velocities of the order of phase velocity of the surface wave. The scheme is viable to achieve beams of tens of keV energy. In the case of a surface plasma wave excited on a single metal-vacuum interface, the field gradient normal to the interface pushes the electrons away from the high field region, limiting the acceleration process. The acceleration energy thus achieved is in agreement with the experimental observations. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22611467-electron-density-plasma-dynamics-colliding-plasma-experiment','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22611467-electron-density-plasma-dynamics-colliding-plasma-experiment">Electron density and plasma dynamics of a colliding plasma experiment</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Wiechula, J., E-mail: wiechula@physik.uni-frankfurt.de; Schönlein, A.; Iberler, M. 2016-07-15 We present experimental results of two head-on colliding plasma sheaths accelerated by pulsed-power-driven coaxial plasma accelerators. The measurements have been performed in a small vacuum chamber with a neutral-gas prefill of ArH{sub 2} at gas pressures between 17 Pa and 400 Pa and load voltages between 4 kV and 9 kV. As the plasma sheaths collide, the electron density is significantly increased. The electron density reaches maximum values of ≈8 ⋅ 10{sup 15} cm{sup −3} for a single accelerated plasma and a maximum value of ≈2.6 ⋅ 10{sup 16} cm{sup −3} for the plasma collision. Overall a raise of the plasma density by a factor ofmore » 1.3 to 3.8 has been achieved. A scaling behavior has been derived from the values of the electron density which shows a disproportionately high increase of the electron density of the collisional case for higher applied voltages in comparison to a single accelerated plasma. Sequences of the plasma collision have been taken, using a fast framing camera to study the plasma dynamics. These sequences indicate a maximum collision velocity of 34 km/s.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2004cosp...35.2083K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2004cosp...35.2083K">Ionospheres of outer planet satellites: The legacy of Galileo and the promise of Cassini</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kliore, A. J.; Nagy, A. F. The Galileo spacecraft was placed into orbit about Jupiter in 1995 and until the end of 2003 it has provided multiple opportunities for the study of the plasma environments of the icy Galilean satellites Europa, Ganymede, and Callisto by means of radio occultation of its S-band (13.5 cm. wavelength) signal. There have been four occultations each by Europa, Ganymede, and Callisto that have provided useful data, in addition to five occultations by the volcanic satellite Io.. Analysis of these data revealed small excursions in the received frequency (of the order of 0.01 Hz, or about 4 parts in 1012), which indicated the presence of tenuous plasma above the surfaces of these bodies. When observed, the maximum electron densities range from about 5 to about 20 x 103 cm-3. The vertical structure of these plasma layers range from classical ionospheric profiles observed at Callisto on two occasions, to multi-peaked structures observed at Europa. On several occasions no discernible plasma was observed. These observations could be explained by a process in which a tenuous neutral atmosphere (about 1010 cm-3), consisting dissociation products of H2O, is created on the trailing hemisphere of the satellite by sputtering from the icy surface by energetic particles of the Jovian magnetosphere. If the trailing hemisphere is at that time also illuminated by the Sun, plasma is produced by photoionization, and is observed by radio occultation. The configuration of this plasma is, however, determined by its interaction with the corotating Jovian magnetospheric plasma, which under certain geometries would lead to the observation of multipeaked structures. The Cassini orbiter, which will be placed into orbit about Saturn in 2004 , will provide at least four occultations of Titan. In contrast to Galileo, Cassini has three downlink frequencies - in addition to s-band, it also has x-band (˜ 5.5 cm), and Ka-band (˜ 1 cm) downlinks, which will provide excellent data on Titan's ionosphere and plasma environment during the standard tour of the Saturnian system, and possibly of some of the icy satellites during the extended mission.. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015PSST...24d5003S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015PSST...24d5003S">Atomic and molecular hydrogen gas temperatures in a low-pressure helicon plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Samuell, Cameron M.; Corr, Cormac S. 2015-08-01 Neutral gas temperatures in hydrogen plasmas are important for experimental and modelling efforts in fusion technology, plasma processing, and surface modification applications. To provide values relevant to these application areas, neutral gas temperatures were measured in a low pressure (< 10 mTorr) radiofrequency helicon discharge using spectroscopic techniques. The atomic and molecular species were not found to be in thermal equilibrium with the atomic temperature being mostly larger then the molecular temperature. In low power operation (< 1 kW), the molecular hydrogen temperature was observed to be linearly proportional to the pressure while the atomic hydrogen temperature was inversely proportional. Both temperatures were observed to rise linearly with input power. For high power operation (5-20 kW), the molecular temperature was found to rise with both power and pressure up to a maximum of approximately 1200 K. Spatially resolved measurements near a graphite target demonstrated localised cooling near the sample surface. The temporal evolution of the molecular gas temperature during a high power 1.1 ms plasma pulse was also investigated and found to vary considerably as a function of pressure. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23749586','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23749586">Pharmacokinetic interaction of enrofloxacin/trimethoprim combination following single-dose intraperitoneal and oral administration in rats.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Choi, Myung-Jin; Yohannes, Sileshi Belew; Lee, Seung-Jin; Damte, Dereje; Kim, Jong-Choon; Suh, Joo-Won; Park, Seung-Chun 2014-03-01 The pharmacokinetic interaction of enrofloxacin and trimethoprim was evaluated after single-dose intraperitoneal or oral co-administration in rats. Plasma concentrations of the two drugs were determined by high-performance liquid chromatography. Following intraperitoneal combination, a significant (P < 0.05) increase in mean values of plasma half-life (t 1/2) and maximum plasma concentration (C max) was observed for enrofloxacin and trimethoprim, respectively. There was a significant (P < 0.05) increase in mean values of area under the plasma drug concentration versus time from time zero to infinity (AUC0-∞) and C max between combined oral doses (10, 30 and 100 mg/kg) of both antibacterial drugs. Also, after oral conjugation a significant difference in mean values of MRT0-∞ was observed between lower (10 mg/kg) and higher (100 mg/kg) doses of both drugs. A significant increase in pharmacokinetic parameters of both drugs in combined intraperitoneal and oral doses indicated pharmacokinetic interaction of enrofloxacin and trimethoprim. Further study is recommended in other species of animals. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li class="active">5</li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_6" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li class="active">6</li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="101"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22113469-observation-emission-process-hydrogen-like-nitrogen-pinch-discharge-time-integrated-soft-ray-spectrum-pinhole-image','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22113469-observation-emission-process-hydrogen-like-nitrogen-pinch-discharge-time-integrated-soft-ray-spectrum-pinhole-image">Observation of emission process in hydrogen-like nitrogen Z-pinch discharge with time integrated soft X-ray spectrum pinhole image</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Sakai, Y.; Kumai, H.; Nakanishi, Y. 2013-02-15 The emission spectra of hydrogen-like nitrogen Balmer at the wavelength of 13.4 nm in capillary Z-pinch discharge plasma are experimentally examined. Ionization to fully strip nitrogen at the pinch maximum, and subsequent rapid expansion cooling are required to establish the population inversion between the principal quantum number of n = 2 and n = 3. The ionization and recombination processes with estimated plasma parameters are evaluated by utilizing a time integrated spectrum pinhole image containing radial spatial information. A cylindrical capillary plasma is pinched by a triangular pulsed current with peak amplitude of 50 kA and pulse width of 50more » ns.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012AnGeo..30.1259X','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012AnGeo..30.1259X">Features of highly structured equatorial plasma irregularities deduced from CHAMP observations</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Xiong, C.; Lühr, H.; Ma, S. Y.; Stolle, C.; Fejer, B. G. 2012-08-01 In this study five years of CHAMP (Challenging Mini-satellite Payload) fluxgate magnetometer (FGM) data is used to investigate the characteristics of Equatorial Plasma Bubbles (EPBs). We filtered the FGM data by using band-passes with four different cut-off periods to get the EPBs with different maximum spatial scale sizes in the meridional plane ranging from 76-608 km. Associated with the EPB observations at about 400 km, the typical altitude of CHAMP during the year 2000-2005, we also investigate the post-sunset equatorial vertical plasma drift data from ROCSAT-1 (Republic of China Satellite 1). Since the height of the F-layer is highly correlated with the vertical plasma drift and solar flux, we sorted the ROCSAT-1 data into different groups by F10.7. From the integrated vertical drift we have estimated the post-sunset uplift of the ionosphere. By comparing the properties of EPB occurrence for different scale sizes with the global distribution of plasma vertical uplift, we have found that EPBs reaching higher altitudes are more structured than those which are sampled by CHAMP near the top side of the depleted fluxtube. Such a result is in accord with 3-D model simulations (Aveiro and Hysell, 2010). Small-scale EPB structures are observed by CHAMP when the irregularities reach apex heights of 800 km and more. Such events are encountered primarily in the Brazilian sector during the months around November, when the post-sunset vertical plasma drift is high. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/5445024-solar-cycle-dependence-location-shape-venus-bow-shock','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/5445024-solar-cycle-dependence-location-shape-venus-bow-shock">The solar cycle dependence of the location and shape of the Venus bow shock</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Zhang, T.L.; Luhmann, J.G.; Russell, C.T. 1990-09-01 From initial Pioneer Venus observations during the maximum of solar cycle 21 it was evident that the position of the Venus bow shock varies with solar activity. The bow shock radius in the terminator plane changed from 2.4 R{sub v} to 2.1 R{sub v} as solar activity went from maximum to minimum and, as activity has increased in cycle 22, it has increased again. The recent studies of the subsolar region show that the altitude of the nose of the bow shock varies from 1,600 km at solar minimum to 2,200 km at intermediate solar activity in concert with themore » terminator altitude so that the shape remains constant and only the size varies during the solar cycle. Using a gas dynamic model and the observed bow shock location, the authors infer the variation in the size of the effective obstacle during the solar cycle. At solar maximum, the effective obstacle is larger than the ionopause as if a magnetic barrier exists in the inner magnetosheath. This magnetic barrier acts as the effective obstacle deflecting the magnetosheath plasma about 500 km above the surface of Venus. However, at solar minimum the effective obstacle is well below the subsolar ionopause, and some absorption of the solar wind plasma by the Venus neutral atmosphere is suggested by these observations. The dependence of the solar cycle variation of the shock position on the orientation of the interplanetary magnetic field reinforces the idea that planetary ion pickup is important in the interaction of the solar wind with Venus.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/5258689-new-method-determining-temperature-emission-measure-during-solar-flares-from-light-curves-soft-ray-line-fluxes','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/5258689-new-method-determining-temperature-emission-measure-during-solar-flares-from-light-curves-soft-ray-line-fluxes">New method for determining temperature and emission measure during solar flares from light curves of soft X-ray line fluxes</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Bornmann, P.L. I describe a new property of soft X-ray line fluxes observed during the decay phase of solar flares and a technique for using this property to determine the plasma temperature and emission measure as functions of time. The soft X-ray line fluxes analyzed in this paper were observed during the decay phase of the 1980 November 5 flare by the X-Ray Polychromator (XRP) instrument on board the Solar Maximum Mission (SMM). The resonance, intercombination, and forbidden lines of Ne IX, Mg XI, Si XIII, S XV, Ca XIX, and Fe XXV, as well as the Lyman-..cap alpha.. line of Omore » VIII and the resonance lines of Fe XIX, were observed. The rates at which the observed line fluxes decayed were not constant. For all but the highest temperature lines observed, the rate changed abruptly, causing the fluxes to fall at a more rapid rate later in the flare decay. These changes occurred at earlier times for lines formed at higher temperatures. This behavior is proposed to be due to the decreasing temperature of the flare plasma tracking the rise and subsequent fall of each line emissivity function. This explanation is used to empirically model the observed light curves and to estimate the temperature and the change in emission measure of the plasma as a function of time during the decay phase. Estimates are made of various plasma parameters based on the model results.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/5496420-dependence-electron-beam-instability-growth-rates-beam-plasma-system-parameters','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/5496420-dependence-electron-beam-instability-growth-rates-beam-plasma-system-parameters">Dependence of electron beam instability growth rates on the beam-plasma system parameters</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Strangeway, R.J. 1982-02-01 Electron beam instabilites are studied by using a simple model for an electron beam streaming through a cold plasma, the beam being of finite width perpendicular to the ambient magnetic field. Through considerations of finite geometry and the coldness of the beam and background plasma, an instability similar to the two stream instability is assumed to be the means for wave growth in the system. Having found the maximum growth rate for one set of beam-plasma system parameters, this maximum growth rate is traced as these parameters are varied. The parameters that describe the system are the beam velocity (v/submore » b/), electron gyrofrequency to ambient electron plasma frequency ratio (..cap omega../sub e//..omega../sub p/e), the beam to background number density ratio (n/sub b//n/sub a/), and the beam width (a). When ..cap omega../sub e//..omega../sub p/e>1, a mode with ..cap omega../sub e/<..omega..<..omega../sub u/hr is found to be unstable, where ..cap omega.. is the wave frequency and ..omega../sub u/hr is the upper hybrid resonance frequency. For low values of n/sub b//n/sub a/ and ..cap omega../sub e/<..omega../sub p/e, this mode is still present with ..omega../sub p/e<..omega..<..omega../sub u/hr. If the beam density is large, n/sub b//n/sub a/approx. =1, the instability occures for frequencies just above the electron gyrofrequency. This mode may well be that observed in laboratory plasma before the system undergoes the beam-plasma discharge. There is another instability present, which occurs for ..omega..approx. =..omega../sub p/e. The growth rates for this mode, which are generally larger than those found for the ..omega..approx. =..omega..uhr mode, are only weakly dependent on ..cap omega../sub d//..omega../sub p/e. That this mode is not always observed in the laboratory implies that some factors not considered in the present theory suppress this mode, specifically, finite beam length.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018RScI...89b3503B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018RScI...89b3503B">A table top experiment to investigate production and properties of a plasma confined by a dipole magnet</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Baitha, Anuj Ram; Kumar, Ashwani; Bhattacharjee, Sudeep 2018-02-01 We report a table top experiment to investigate production and properties of a plasma confined by a dipole magnet. A water cooled, strong, cylindrical permanent magnet (NdFeB) magnetized along the axial direction and having a surface magnetic field of ˜0.5 T is employed to create a dipole magnetic field. The plasma is created by electron cyclotron resonance heating. Visual observations of the plasma indicate that radiation belts appear due to trapped particles, similar to the earth's magnetosphere. The electron temperature lies in the range 2-13 eV and is hotter near the magnets and in a downstream region. It is found that the plasma (ion) density reaches a value close to 2 × 1011 cm-3 and peaks at a radial distance about 3 cm from the magnet. The plasma beta β (β = plasma pressure/magnetic pressure) increases radially outward, and the maximum β for the present experimental system is ˜2%. It is also found that the singly charged ions are dominant in the discharge. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19950039560&hterms=PV+solar&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3DPV%2Bsolar','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19950039560&hterms=PV+solar&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3DPV%2Bsolar">Ion measurements during Pioneer Venus reentry: Implications for solar cycle variation of ion composition and dynamics</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Grebowsky, J. M.; Hartle, R. E.; Kar, J.; Cloutier, P. A.; Taylor, H. A., Jr.; Brace, L. H. 1993-01-01 During the final, low solar activity phase of the Pioneer Venus (PV) mission, the Orbiter Ion Mass Spectrometer (OIMS) measurements found all ion species, in the midnight-dusk sector, reduced in concentration relative to that observed at solar maximum. Molecular ion species comprised a greater part of the total ion concentration as O(+) and H(+) had the greatest depletions. The nightside ionospheric states were strikingly similar to the isolated solar maximum 'disappearing' ionospheres. Both are very dynamic states characterized by a rapidly drifting plasma and 30-100 eV superthermal O(+) ions. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JPhD...50a5201J','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JPhD...50a5201J">The effect of UV radiation from oxygen and argon plasma on the adhesion of organosilicon coatings on polypropylene</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Jaritz, M.; Behm, H.; Hopmann, Ch; Kirchheim, D.; Mitschker, F.; Awakowicz, P.; Dahlmann, R. 2017-01-01 The influence of ultraviolet (UV) radiation from oxygen and argon pretreatment plasmas on a plastic substrate has not been fully understood yet. In particular, its influence on the adhesion properties has not been sufficiently researched so far. This paper addresses this issue by comparing the bond strength of a plasmapolymerized silicon organic coating (SiO x C y H z ) on polypropylene (PP) after oxygen and argon plasma pretreatment and pretreatment by UV radiation emitted by the same plasmas. The UV radiation is isolated from the other species from the plasma by means of a magnesium fluoride (MgF2) optical filter. It could be shown that UV radiation originating from an oxygen plasma has a significant impact on both substrate surface chemistry and coating adhesion. The same maximum bond strength enhancement can be reached by pretreating the polypropylene surface either with pulsed oxygen plasma, or with only the UV radiation from this oxygen plasma. Also, similar surface chemistry and topography modifications are induced. For argon plasma no significant influence of its UV radiation on the substrate could be observed in this study. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26270490','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26270490">The influence of Actinobacillus pleuropneumoniae infection on tulathromycin pharmacokinetics and lung tissue disposition in pigs.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Gajda, A; Bladek, T; Jablonski, A; Posyniak, A 2016-04-01 A tulathromycin concentration and pharmacokinetic parameters in plasma and lung tissue from healthy pigs and Actinobacillus pleuropneumoniae (App)-infected pigs were compared. Tulathromycin was administered intramuscularly (i.m.) to all pigs at a single dose of 2.5 mg/kg. Blood and lung tissue samples were collected during 33 days postdrug application. Tulathromycin concentration in plasma and lung was determined by high-performance liquid chromatography with tandem mass spectrometry (LC-MS/MS) method. The mean maximum plasma concentration (Cmax ) in healthy pigs was 586 ± 71 ng/mL, reached by 0.5 h, while the mean value for Cmax of tulathromycin in infected pigs was 386 ± 97 ng/mL after 0.5 h. The mean maximum tulathromycin concentration in lung of healthy group was calculated as 3412 ± 748 ng/g, detected at 12 h, while in pigs with App, the highest concentration in lung was 3337 ± 937 ng/g, determined at 48 h postdosing. The higher plasma and lung concentrations in pigs with no pulmonary inflammation were observed at the first time points sampling after tulathromycin administration, but slower elimination with elimination half-life t1/2el = 126 h in plasma and t1/2el = 165 h in lung, as well as longer drug persistent in infected pigs, was found. © 2015 John Wiley & Sons Ltd. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1984lock.rept.....H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1984lock.rept.....H">Soft X-ray polychromator for the Solar Maximum Mission</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Haisch, B. M.; Levay, M.; Stern, R. A.; Strong, K. T.; Wolfson, C. J.; Acton, L. W. 1984-12-01 The XRP was designed to measure the following temporal and spatial properties of the active and flaring Sun: electron temperature, departures from steady state, ion kinetic temperatures, and electron density. The Bent Crystal Spectrometer (BCS) is capable of measuring the broadening and blue shifts often observed in the impulsive phase of flares. The six simultaneous line fluxes indicative of six different temperatures of formation observable by the Flat Crystal Spectrometer (FCS) allows the derivation of the differential emission measure of the plasma at each raster point. During the operational periods of the XRP hundreds of flares of C-level (GOES classification) were observed and brighter in both the FCS and BCS, including 5 X-flares. Associated theoretical work in atomic physics, stimulated in part by the promise of XRP measurements, has benefitted from the experimental data on solar plasmas which the XRP has provided in abundance. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19850024783','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19850024783">Soft X-ray polychromator for the Solar Maximum Mission</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Haisch, B. M.; Levay, M.; Stern, R. A.; Strong, K. T.; Wolfson, C. J.; Acton, L. W. 1984-01-01 The XRP was designed to measure the following temporal and spatial properties of the active and flaring Sun: electron temperature, departures from steady state, ion kinetic temperatures, and electron density. The Bent Crystal Spectrometer (BCS) is capable of measuring the broadening and blue shifts often observed in the impulsive phase of flares. The six simultaneous line fluxes indicative of six different temperatures of formation observable by the Flat Crystal Spectrometer (FCS) allows the derivation of the differential emission measure of the plasma at each raster point. During the operational periods of the XRP hundreds of flares of C-level (GOES classification) were observed and brighter in both the FCS and BCS, including 5 X-flares. Associated theoretical work in atomic physics, stimulated in part by the promise of XRP measurements, has benefitted from the experimental data on solar plasmas which the XRP has provided in abundance. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1996APS..DPP.6IA01P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1996APS..DPP.6IA01P">The TSS-1R Results - the Physics of Current Collection in Magnetized Plasmas Revised</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Papadopoulos, Konstantinos 1996-11-01 The Tethered Satellite System (TSS-1R) was deployed from the space shuttle "Columbia" (STS-75 Mission) on February 24, 1996. The satellite was deployed to a distance of 19.7 km above the shuttle. The system operated nominally over its deployment phase which lasted 5.5 hours. A defect in the tether insulation inside the orbiter caused a local discharge which led to a tether break. Data collected before and during the break revealed a host of new physics phenomena concerning the current collection by charged bodies in space moving at orbital velocities. The maximum EMF observed during the mission was 3.8 kV and the maximum current exceeded 1A. Power generation of several kW's was demonstrated. The current collected was significantly larger than expected by space charged limited flow in magnetized and even unmagnetized plasmas. For example the 1A current was collected with less than 1 kV potential instead of the 20 kV given by previous theories. The presentation will review the fascinating results of the TSS-1R and will discuss the ongoing physics analysis of the observed phenomena. *In collaboration with A. Drobot and C.L. Chang of SAIC. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28087972','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28087972">Lack of effect of oral cabotegravir on the pharmacokinetics of a levonorgestrel/ethinyl oestradiol-containing oral contraceptive in healthy adult women.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Trezza, Christine; Ford, Susan L; Gould, Elizabeth; Lou, Yu; Huang, Chuyun; Ritter, James M; Buchanan, Ann M; Spreen, William; Patel, Parul 2017-07-01 This study aimed to investigate whether cabotegravir (CAB), an integrase inhibitor in development for treatment and prevention of human immunodeficiency virus-1, influences the pharmacokinetics (PK) of a levonorgestrel (LNG) and ethinyl oestradiol (EO)-containing oral contraceptive (OC) in healthy women. In this open-label, fixed-sequence crossover study, healthy female subjects received LNG 0.15 mg/EO 0.03 mg tablet once daily Days 1-10 alone and with oral CAB 30 mg once daily Days 11-21. At the end of each treatment period, subjects underwent predose sampling for concentrations of follicle-stimulating hormone, luteinizing hormone, and progesterone and serial PK sampling for plasma LNG, EO, and CAB concentrations. Twenty women were enrolled, and 19 completed the study. One subject was withdrawn due to an adverse event unrelated to study medications. Geometric least squares mean ratios (90% confidence interval) of LNG + CAB vs. LNG alone for LNG area under the plasma concentration-time curve over the dosing interval of duration τ and maximum observed plasma concentration were 1.12 (1.07-1.18) and 1.05 (0.96-1.15), respectively. Geometric least squares mean ratio (90% confidence interval) of EO + CAB vs. EO alone for EO area under the plasma concentration-time curve over the dosing interval of duration τ and maximum observed plasma concentration were 1.02 (0.97-1.08) and 0.92 (0.83-1.03), respectively. Steady-state CAB PK parameters were comparable to historical values. There was no apparent difference in mean luteinizing hormone, follicle-stimulating hormone, and progesterone concentrations between periods. No clinically significant trends in laboratory values, vital signs, or electrocardiography values were observed. Repeat doses of oral CAB had no significant effect on LNG/EO PK or pharmacodynamics, which supports CAB coadministration with LNG/EO OCs in clinical practice. © 2017 ViiV Healthcare. British Journal of Clinical Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19860010670','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19860010670">RF wave observations in beam-plasma discharge</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Bernstein, W. 1986-01-01 The Beam Plasma Discharge (BPD) was produced in the large vacuum chamber at Johnson Space Center (20 x 30 m) using an energetic electron beam of moderately high perveance. A more complete expression of the threshold current I sub c taking into account the pitch angle injection dependence is given. Ambient plasma density inferred from wave measurements under various beam conditions are reported. Maximum frequency of the excited RF band behaves differently than the frequency of the peak amplitude. The latter shows signs of parabolic saturation consistent with the light data. Beam plasma state (pre-BPD or BPD) does not affect the pitch angle dependence. Unexpected strong modulation of the RF spectrum at half odd integer of the electron cyclotron frequency (n + 1/2)f sub ce is reported (5 n 10). Another new feature, the presence of wave emission around 3/2 f sub ce for I sub b is approximate I sub c is reported. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/527672-ion-energy-distributions-silane-hydrogen-plasmas','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/527672-ion-energy-distributions-silane-hydrogen-plasmas">Ion energy distributions in silane-hydrogen plasmas</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Hamers, E.A.G.; Sark, W.G.J.H.M. van; Bezemer, J. 1996-12-31 For the first time ion energy distributions (IED) of different ions from silane-hydrogen (SiH{sub 4}-H{sub 2}) RF plasmas are presented, i.e., the distributions of SiH{sub 3}{sup +}, SiH{sub 2}{sup +} and Si{sub 2}H{sub 4}{sup +}. The energy distributions of SiH{sub 3}{sup +} and SiH{sub 2}{sup +} ions show peaks, which are caused by a charge exchange process in the sheath. A method is presented by which the net charge density in the sheath is determined from the plasma potential and the energy positions of the charge exchange peaks. Knowing the net charge density in the sheath and the plasma potential,more » the sheath thickness can be determined and an estimation of the absolute ion fluxes can be made. The flux of ions can, at maximum, account for 10% of the observed deposition rate.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1340288-experimental-studies-high-confinement-mode-plasma-response-non-axisymmetric-magnetic-perturbations-asdex-upgrade','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1340288-experimental-studies-high-confinement-mode-plasma-response-non-axisymmetric-magnetic-perturbations-asdex-upgrade">Experimental studies of high-confinement mode plasma response to non-axisymmetric magnetic perturbations in ASDEX Upgrade</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a> Suttrop, Wolfgang; Kirk, A.; Nazikian, R.; ... 2016-11-22 Here, the interaction of externally applied small non-axisymmetric magnetic perturbations (MP) with tokamak high-confinement mode (H-mode) plasmas is reviewed and illustrated by recent experiments in ASDEX Upgrade. The plasma response to the vacuum MP field is amplified by stable ideal kink modes with low toroidal mode number n driven by the H-mode edge pressure gradient (and associated bootstrap current) which is experimentally evidenced by an observable shift of the poloidal mode number m away from field alignment (m = qn, with q being the safety factor) at the response maximum. A torque scan experiment demonstrates the importance of the perpendicular electron flow for shielding of the resonant magnetic perturbation, as expected from a two-fluid MHD picture. Two significant effects of MP occur in H-mode plasmas at low pedestal collisionality,more » $$\ </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018PSST...27e5006G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018PSST...27e5006G">Preferential vibrational excitation in microwave nitrogen plasma assessed by Raman scattering</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Gatti, N.; Ponduri, S.; Peeters, F. J. J.; van den Bekerom, D. C. M.; Minea, T.; Tosi, P.; van de Sanden, M. C. M.; van Rooij, G. J. 2018-05-01 Vibrational activation of N2 molecules in a flowing microwave plasma is investigated in the context of utilising electrical energy for chemical conversion. Spatial profiles of rotational (T r ) and vibrational (T v ) temperatures are measured by Raman scattering. Maximum values of T r = 3500 K and T v = 6000 K were observed in the centre of the plasma at low pressure (50 mbar). A detailed quantification of the local energy content shows how the strong non-equilibrium character of low pressure discharges compares with a closer-to-equilibrium energy distribution at higher pressures. Measurements performed downstream of the plasma display the ability of the microwave flowing reactor to deliver up to 48% of the specific energy input (SEI) into internal degrees of freedom of the gas molecules. Specifically, 23% of the SEI is loaded into the vibrational mode, which is potentially available to enhance chemical reactivity of endothermic reactions. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24150390','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24150390">Generation and confinement of microwave gas-plasma in photonic dielectric microstructure.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Debord, B; Jamier, R; Gérôme, F; Leroy, O; Boisse-Laporte, C; Leprince, P; Alves, L L; Benabid, F 2013-10-21 We report on a self-guided microwave surface-wave induced generation of ~60 μm diameter and 6 cm-long column of argon-plasma confined in the core of a hollow-core photonic crystal fiber. At gas pressure of 1 mbar, the micro-confined plasma exhibits a stable transverse profile with a maximum gas-temperature as high as 1300 ± 200 K, and a wall-temperature as low as 500 K, and an electron density level of 10¹⁴ cm⁻³. The fiber guided fluorescence emission presents strong Ar⁺ spectral lines in the visible and near UV. Theory shows that the observed combination of relatively low wall-temperature and high ionisation rate in this strongly confined configuration is due to an unprecedentedly wide electrostatic space-charge field and the subsequent ion acceleration dominance in the plasma-to-gas power transfer. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70031461','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70031461">Responses by pacific halibut to air exposure: Lack of correspondence among plasma constituents and mortality</a> <a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a> Davis, M.W.; Schreck, C.B. 2005-01-01 Age-1 and age-2 Pacific halibut Hippoglossus stenolepis were exposed to a range of times in air (0-60 min) and air temperatures (10??C or 16??C) that simulated conditions on deck after capture to test for correspondence among responses in plasma constituents and mortality. Pacific halibut mortality generally did not correspond with cortisol, glucose, sodium, and potassium since the maximum observed plasma concentrations were reached after exposure to 30 min in air, while significant mortality occurred only after exposure to 40 min in air for age-1 fish and 60 min in air for age-2 fish. Predicting mortality in discarded Pacific halibut using these plasma constituents does not appear to be feasible. Lactate concentrations corresponded with mortality in age-1 fish exposed to 16??C and may be useful predictors of discard mortality under a limited set of fishing conditions. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018NucFu..58e6027K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018NucFu..58e6027K">Influence of sub-surface damage evolution on low-energy-plasma-driven deuterium permeation through tungsten</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kapser, Stefan; Balden, Martin; Fiorini da Silva, Tiago; Elgeti, Stefan; Manhard, Armin; Schmid, Klaus; Schwarz-Selinger, Thomas; von Toussaint, Udo 2018-05-01 Low-energy-plasma-driven deuterium permeation through tungsten at 300 K and 450 K has been investigated. Microstructural analysis by scanning electron microscopy, assisted by focused ion beam, revealed sub-surface damage evolution only at 300 K. This damage evolution was correlated with a significant evolution of the deuterium amount retained below the plasma-exposed surface. Although both of these phenomena were observed for 300 K exposure temperature only, the deuterium permeation flux at both exposure temperatures was indistinguishable within the experimental uncertainty. The permeation flux was used to estimate the maximum ratio of solute-deuterium to tungsten atoms during deuterium-plasma exposure at both temperatures and thus in the presence and absence of damage evolution. Diffusion-trapping simulations revealed the proximity of damage evolution to the implantation surface as the reason for an only insignificant decrease of the permeation flux. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li class="active">6</li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_7" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li class="active">7</li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="121"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015JNuM..463.1252T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015JNuM..463.1252T">High heat-flux self-rotating plasma-facing component: Concept and loading test in TEXTOR</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Terra, A.; Sergienko, G.; Hubeny, M.; Huber, A.; Mertens, Ph.; Philipps, V.; The Textor Team 2015-08-01 This contribution reports on the concept of a circular self-rotating and temperature self-stabilising plasma-facing component (PFC), and test of a related prototype in TEXTOR tokamak. This PFC uses the Lorentz force induced by plasma current and magnet field (J × B) to create a torque applied on metallic discs which produce a rotational movement. Additional thermionic current, present at high operation temperatures, brings additional temperature stabilisation ability. This self-rotating disk limiter was exposed to plasma in the TEXTOR tokamak under different radial positions to vary the heat flux. This disk structure shows the interesting ability to stabilise its maximum temperature through the fact that the self-induced rotation is modulated by the thermal emission current. It was observed that the rotation speed increased following both the current collected by the limiter, and the temperature of the tungsten disks. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1389974','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/1389974">An ultra-high gain and efficient amplifier based on Raman amplification in plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Vieux, G.; Cipiccia, S.; Grant, D. W. Raman amplification arising from the excitation of a density echelon in plasma could lead to amplifiers that significantly exceed current power limits of conventional laser media. Here we show that 1–100 J pump pulses can amplify picojoule seed pulses to nearly joule level. The extremely high gain also leads to significant amplification of backscattered radiation from “noise”, arising from stochastic plasma fluctuations that competes with externally injected seed pulses, which are amplified to similar levels at the highest pump energies. The pump energy is scattered into the seed at an oblique angle with 14 J sr -1, and net gainsmore » of more than eight orders of magnitude. The maximum gain coefficient, of 180 cm -1, exceeds high-power solid-state amplifying media by orders of magnitude. The observation of a minimum of 640 J sr -1 directly backscattered from noise, corresponding to ≈10% of the pump energy in the observation solid angle, implies potential overall efficiencies greater than 10%.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1389974-ultra-high-gain-efficient-amplifier-based-raman-amplification-plasma','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1389974-ultra-high-gain-efficient-amplifier-based-raman-amplification-plasma">An ultra-high gain and efficient amplifier based on Raman amplification in plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a> Vieux, G.; Cipiccia, S.; Grant, D. W.; ... 2017-05-25 Raman amplification arising from the excitation of a density echelon in plasma could lead to amplifiers that significantly exceed current power limits of conventional laser media. Here we show that 1–100 J pump pulses can amplify picojoule seed pulses to nearly joule level. The extremely high gain also leads to significant amplification of backscattered radiation from “noise”, arising from stochastic plasma fluctuations that competes with externally injected seed pulses, which are amplified to similar levels at the highest pump energies. The pump energy is scattered into the seed at an oblique angle with 14 J sr -1, and net gainsmore » of more than eight orders of magnitude. The maximum gain coefficient, of 180 cm -1, exceeds high-power solid-state amplifying media by orders of magnitude. The observation of a minimum of 640 J sr -1 directly backscattered from noise, corresponding to ≈10% of the pump energy in the observation solid angle, implies potential overall efficiencies greater than 10%.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20060024879&hterms=Continuum+theory&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3DContinuum%2Btheory','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20060024879&hterms=Continuum+theory&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3DContinuum%2Btheory">Is the Linear Mode Conversion Theory Viable for Generating Kilometric Continuum?</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Boardsen, Scott A.; Green, James L.; Hashimoto, K.; Gallagher, Dennis L.; Webb, P. A. 2006-01-01 Kilometric Continuum (KC) usually exhibits a complicated banded radiation pattern observed in frequency time spectrograms. Can the number of bands, the frequency range over which the bands are observed, and their time variation be explained with Linear Mode Conversion Theory (LMCT) using realistic plasmapause models and Extreme Ultraviolet (EUV) plasmaspheric observations? In this paper we compare KC observations with simulated frequency emission bands based on LMCT for a number of cases. In LMCT the allowed frequency range across the equatorial plasmapause is restricted to frequencies much greater than the electron cyclotron frequency (fce) and less than the maximum plasma frequency in this region. Fce also determines the number of allowed bands in this range. Is the observed frequency range and number of bands consistent with the predications of LMCT? Can irregularities in the shape of plasmaspheric structures like notches be observed in the time variations of KC emissions? We will investigate these and other questions. Simulated radiation patterns will be generated by ray tracing calculations in the L-O mode from the radio window at the near equatorial plasmapause. The KC observations used in this study are from the Plasma Wave Instrument on the Geotail spacecraft and from the Radio Plasma Imager on the IMAGE spacecraft. The plasmasphere and plasmapause will be derived either from plasmasphere simulations, from images by the EUV imager on the IMAGE spacecraft, and by using empirical models. In situ plasma density measurements from a number of spacecraft will also be used in order to reconstruct the plasmasphere for these case studies. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20484610','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20484610">Pharmacokinetics of gabapentin in a novel gastric-retentive extended-release formulation: comparison with an immediate-release formulation and effect of dose escalation and food.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Chen, Cuiping; Cowles, Verne E; Hou, Eddie 2011-03-01 The objectives of the 3 phase I studies described herein were (1) to compare the pharmacokinetics of gabapentin delivered from a novel gastric-retentive dosage form vs an immediate-release formulation, (2) to assess the dose proportionality of the gastric-retentive extended-release formulation, and (3) to determine the effect of food on the pharmacokinetics of gabapentin delivered from this formulation. The time to reach maximum plasma concentration (t(max)) was extended for gabapentin delivered from the gastric-retentive extended-release formulation compared with the immediate-release formulation. A dose-related increase in both the maximum plasma concentration (C(max)) and the area under the plasma concentration-time curve (AUC) was observed as the gabapentin dose increased from 600 to 2400 mg. Fed status and increased fat content delayed t(max) and enhanced C(max) and AUC in proportion to the fat content. The pharmacokinetics of gabapentin delivered from this extended-release formulation allows a reduced dosing frequency while maintaining bioavailability and possibly diminishing the occurrence of adverse events attributable to a slower increase to the peak concentration compared with the immediate-release dosage form. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3732421','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3732421">Comparison of the protective effects of ferulic acid and its drug-containing plasma on primary cultured neonatal rat cardiomyocytes with hypoxia/reoxygenation injury</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Ren, Cong; Bao, Yong-rui; Meng, Xian-sheng; Diao, Yun-peng; Kang, Ting-guo 2013-01-01 Backgroud: To simulate the ischemia-reperfusion injury in vivo, hypoxia/reoxygenation injury model was established in vitro and primary cultured neonatal rat cardiomyocytes were underwent hypoxia with hydrosulfite (Na2S2O4) for 1 h followed by 1 h reoxygenation. Materials and Methods: Determination the cell viability by MTT colorimetric assay. We use kit to detect the activity of lactate dehydrogenase (LDH), Na+-K+-ATPase and Ca2+-ATPase. Do research on the effect which ferulic acid and its drug-containing plasma have to self-discipline, conductivity, action potential duration and other electrophysiological phenomena of myocardial cells by direct observation using a microscope and recording method of intracellular action potential. Results: The experimental datum showed that both can reduce the damage hydrosulfite to myocardial cell damage and improve myocardial viability, reduce the amount of LDH leak, increase activity of Na+-K+-ATPase, Ca2+-ATPase, and increase APA (Action potential amplitude), Vmax (Maximum rate of depolarization) and MPD (Maximum potential diastolic). Conclusion: Taken together, therefore, we can get the conclusion that ferulic acid drug-containing plasma has better protective effect injured myocardial cell than ferulic acid. PMID:23930002 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014ChPhB..23f5205C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014ChPhB..23f5205C">Observation and analysis of halo current in EAST</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Chen, Da-Long; Shen, Biao; Qian, Jin-Ping; Sun, You-Wen; Liu, Guang-Jun; Shi, Tong-Hui; Zhuang, Hui-Dong; Xiao, Bing-Jia 2014-06-01 Plasma in a typically elongated cross-section tokamak (for example, EAST) is inherently unstable against vertical displacement. When plasma loses the vertical position control, it moves downward or upward, leading to disruption, and a large halo current is generated helically in EAST typically in the scrape-off layer. When flowing into the vacuum vessel through in-vessel components, the halo current will give rise to a large J × B force acting on the vessel and the in-vessel components. In EAST VDE experiment, part of the eddy current is measured in halo sensors, due to the large loop voltage. Primary experimental data demonstrate that the halo current first lands on the outer plate and then flows clockwise, and the analysis of the information indicates that the maximum halo current estimated in EAST is about 0.4 times the plasma current and the maximum value of TPF × Ih/IP0 is 0.65, furthermore Ih/Ip0 and TPF × Ih/Ip0 tend to increase with the increase of Ip0. The test of the strong gas injection system shows good success in increasing the radiated power, which may be effective in reducing the halo current. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/21347116-generation-zonal-flows-electrostatic-drift-waves-electron-positron-ion-plasmas','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/21347116-generation-zonal-flows-electrostatic-drift-waves-electron-positron-ion-plasmas">Generation of zonal flows by electrostatic drift waves in electron-positron-ion plasmas</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Kaladze, T. D.; I. Vekua Institute of Applied Mathematics, Tbilisi State University, 2 University Str., 0186 Tbilisi; Shad, M. 2010-02-15 Generation of large-scale zonal flows by comparatively small-scale electrostatic drift waves in electron-positron-ion plasmas is considered. The generation mechanism is based on the parametric excitation of convective cells by finite amplitude drift waves having arbitrary wavelengths (as compared with the ion Larmor radius of plasma ions at the plasma electron temperature). Temperature inhomogeneity of electrons and positrons is taken into account assuming ions to be cold. To describe the generation of zonal flow generalized Hasegawa-Mima equation containing both vector and two scalar (of different nature) nonlinearities is used. A set of coupled equations describing the nonlinear interaction of drift wavesmore » and zonal flows is deduced. Explicit expressions for the maximum growth rate as well as for the optimal spatial dimensions of the zonal flows are obtained. Enriched possibilities of zonal flow generation with different growth rates are revealed. The present theory can be used for interpretations of drift wave observations in laboratory and astrophysical plasmas.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015PhPl...22d3516W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015PhPl...22d3516W">Experimental characterization of a coaxial plasma accelerator for a colliding plasma experiment</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Wiechula, J.; Hock, C.; Iberler, M.; Manegold, T.; Schönlein, A.; Jacoby, J. 2015-04-01 We report experimental results of a single coaxial plasma accelerator in preparation for a colliding plasma experiment. The utilized device consisted of a coaxial pair of electrodes, accelerating the plasma due to J ×B forces. A pulse forming network, composed of three capacitors connected in parallel, with a total capacitance of 27 μF was set up. A thyratron allowed to switch the maximum applied voltage of 9 kV. Under these conditions, the pulsed currents reached peak values of about 103 kA. The measurements were performed in a small vacuum chamber with a neutral-gas prefill at gas pressures between 10 Pa and 14 000 Pa. A gas mixture of ArH2 with 2.8% H2 served as the discharge medium. H2 was chosen in order to observe the broadening of the Hβ emission line and thus estimate the electron density. The electron density for a single plasma accelerator reached peak values on the order of 1016 cm-3 . Electrical parameters, inter alia inductance and resistance, were determined for the LCR circuit during the plasma acceleration as well as in a short circuit case. Depending on the applied voltage, the inductance and resistance reached values ranging from 194 nH to 216 nH and 13 mΩ to 23 mΩ, respectively. Furthermore, the plasma velocity was measured using a fast CCD camera. Plasma velocities of 2 km/s up to 17 km/s were observed, the magnitude being highly correlated with gas pressure and applied voltage. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1997PhRvB..56.6642F','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1997PhRvB..56.6642F">Hydrogen molecules and hydrogen-related defects in crystalline silicon</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Fukata, N.; Sasaki, S.; Murakami, K.; Ishioka, K.; Nakamura, K. G.; Kitajima, M.; Fujimura, S.; Kikuchi, J.; Haneda, H. 1997-09-01 We have found that hydrogen exists in molecular form in crystalline silicon treated with hydrogen atoms in the downstream of a hydrogen plasma. The vibrational Raman line of hydrogen molecules is observed at 4158 cm-1 for silicon samples hydrogenated between 180 and 500 °C. The assignment of the Raman line is confirmed by its isotope shift to 2990 cm-1 for silicon treated with deuterium atoms. The Raman intensity has a maximum for hydrogenation at 400 °C. The vibrational Raman line of the hydrogen molecules is broad and asymmetric. It consists of at least two components, possibly arising from hydrogen molecules in different occupation sites in crystalline silicon. The rotational Raman line of hydrogen molecules is observed at 590 cm-1. The Raman band of Si-H stretching is observed for hydrogenation temperatures between 100 and 500 °C and the intensity has a maximum for hydrogenation at 250 °C. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19860049509&hterms=thermal+noise&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dthermal%2Bnoise','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19860049509&hterms=thermal+noise&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dthermal%2Bnoise">Plasma diagnosis from thermal noise and limits on dust flux or mass in comet Giacobini-Zinner</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Meyer-Vernet, N.; Couturier, P.; Hoang, S.; Perche, C.; Steinberg, J. L.; Fainberg, J. 1986-01-01 Thermal noise spectroscopy was used to measure the density and temperature of the main (cold) electron plasma population during two hours around the point of closest approach of the International Cometary Explorer (ICE) to comet Giacobini-Zinner. The time resolution was 18 seconds in the plasma tail and 54 seconds elsewhere. Near the tail axis, the maximum plasma density was 670/cu cm and the temperature slightly above one volt. Away from the axis, the plasma density dropped to 100/cu cm over 2000 km, then decreased to 10/cu cm over 15,000 km; at the plasma tail, the density fluctuated between 10 and 30/cu cm, and the temperature, between 100,000 and 400,000 K. No evidence was found of grain impact on the spacecraft or antennas in the plasma tail. This yields an upper limit for the dust flux or particle mass, indicating either fluxes or masses in the tail smaller than those implied by models or an anomalous grain structure. Outside the tail, and particularly near 100,000 km from its axis, impulsive noises indicating plasma turbulence were observed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26927329','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26927329">Increased coagulation and fibrinolytic potential of solvent-detergent plasma: a comparative study between Omniplasma and fresh frozen plasma.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> van Beers, J J B C; van Egmond, L T; Wetzels, R J H; Verhezen, P W M; Beckers, E A M; van Oerle, R; Spronk, H M H; Straat, R J M H E; Henskens, Y M C 2016-07-01 In this study, differences in levels of proteins involved in coagulation and fibrinolysis were compared between fresh frozen (quarantine plasma) and Omniplasma. Furthermore, thawing conditions and plasma stability after thawing were studied. 10 Omniplasma and 10 quarantine plasma units were used to study different procoagulation, anticoagulation and fibrinolytic parameters. Analysis took place at different time-points during plasma storage at 2-6°C. At baseline, significant reduced levels of factor V, free protein S, α2-antiplasmin and tPA-induced ROTEM lysis time were observed in Omniplasma as compared to quarantine plasma. Moreover, thrombin generation, IXa-AT complex levels and factor XIa were significantly increased in Omniplasma. The majority of the parameters studied remained stable in Omniplasma 48 h after thawing, with the exception of factor VIII (decrease) and IXa-AT (increase). Our results suggest an increased coagulation potential, presumingly as a result of contact activation during the production process and also, an increased fibrinolytic potential in Omniplasma. The stability of Omniplasma, based upon the different parameters studied, is comparable to Q-plasma. A maximum post-thawing time of 48 hfor Omniplasma can be suggested. © 2016 International Society of Blood Transfusion. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22479665-fluid-simulation-bias-effect-inductive-capacitive-discharges','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22479665-fluid-simulation-bias-effect-inductive-capacitive-discharges">Fluid simulation of the bias effect in inductive/capacitive discharges</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Zhang, Yu-Ru; Research Group PLASMANT, Department of Chemistry, University of Antwerp, Universiteitsplein 1, Wilrijk, BE-2610 Antwerp; Gao, Fei Computer simulations are performed for an argon inductively coupled plasma (ICP) with a capacitive radio-frequency bias power, to investigate the bias effect on the discharge mode transition and on the plasma characteristics at various ICP currents, bias voltages, and bias frequencies. When the bias frequency is fixed at 13.56 MHz and the ICP current is low, e.g., 6 A, the spatiotemporal averaged plasma density increases monotonically with bias voltage, and the bias effect is already prominent at a bias voltage of 90 V. The maximum of the ionization rate moves toward the bottom electrode, which indicates clearly the discharge mode transition in inductive/capacitivemore » discharges. At higher ICP currents, i.e., 11 and 13 A, the plasma density decreases first and then increases with bias voltage, due to the competing mechanisms between the ion acceleration power dissipation and the capacitive power deposition. At 11 A, the bias effect is still important, but it is noticeable only at higher bias voltages. At 13 A, the ionization rate is characterized by a maximum at the reactor center near the dielectric window at all selected bias voltages, which indicates that the ICP power, instead of the bias power, plays a dominant role under this condition, and no mode transition is observed. Indeed, the ratio of the bias power to the total power is lower than 0.4 over a wide range of bias voltages, i.e., 0–300 V. Besides the effect of ICP current, also the effect of various bias frequencies is investigated. It is found that the modulation of the bias power to the spatiotemporal distributions of the ionization rate at 2 MHz is strikingly different from the behavior observed at higher bias frequencies. Furthermore, the minimum of the plasma density appears at different bias voltages, i.e., 120 V at 2 MHz and 90 V at 27.12 MHz.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19900043487&hterms=population+characteristic&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3Dpopulation%2Bcharacteristic*','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19900043487&hterms=population+characteristic&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3Dpopulation%2Bcharacteristic*">Plasma characteristics of upflowing ion beams in the polar cap region</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Chen, M. W.; Ashour-Abdalla, M.; Peterson, W. K.; Moore, T. E.; Persoon, A. M. 1990-01-01 The plasma characteristics of upflowing ion stream events with energies greater than 10 eV in the polar cap region near solar maximum are analyzed. It is found that, in 22 of the 41 polar ion streaming events studied, O(+) is the dominant ion constituent in the upflowing beam components. There are significant amounts of upflowing O(+) in the plasma even during quiet auroral conditions. In one event, the upflowing O(+) population had two components, a cold distribution and a warm one. In another event the O(+) and H(+) temperatures suggested that ionospheric ions are heated. The cold upflowing ion stream component observed in some of the polar ion streaming events exhibited a filamentary nature. A significant amount of He(+) was also found in some of the events studied. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27347823','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27347823">Effect of infusion of equine plasma or 6% hydroxyethyl starch (600/0.75) solution on plasma colloid osmotic pressure in healthy horses.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> McKenzie, Erica C; Esser, Melissa M; McNitt, Sarah E; Payton, Mark E 2016-07-01 OBJECTIVE To compare the effects of equivalent volumes of equine plasma and 6% hydroxyethyl starch (600/0.75) solution (hetastarch) administered IV on plasma colloid osmotic pressure (pCOP) and commonly monitored clinicopathologic variables in horses. ANIMALS 6 healthy mares. PROCEDURES In a randomized, crossover study, horses were administered hetastarch or plasma (both 10 mL/kg, IV) 18 months apart. The pCOP and variables of interest were measured before (baseline), immediately after, and at intervals up to 96 or 120 hours after infusion. Prothrombin and activated partial thromboplastin times were measured before and at 2 and 8 hours after each infusion. RESULTS Prior to hetastarch and plasma infusions, mean ± SEM pCOP was 19.4 ± 0.5 mm Hg and 19.4 ± 0.8 mm Hg, respectively. In general, hetastarch and plasma infusions comparably increased pCOP from baseline for 48 hours, with maximum increases of 2.0 and 2.3 mm Hg, respectively. Mean Hct and hemoglobin, total protein, and albumin concentrations were decreased for a period of 72, 96, or 120 hours after hetastarch infusion with maximum decrements of 8.8%, 3.2 g/dL, 1.2 g/dL, and 0.6 g/dL, respectively. Plasma infusion decreased (albeit not always significantly) hemoglobin concentration and Hct for 20 and 24 hours (maximum changes of 1.5 g/dL and 6.6%, respectively) and increased total solids concentration (maximum change of 0.6 g/dL) for 48 hours. Platelet count and coagulation times were minimally affected. CONCLUSIONS AND CLINICAL RELEVANCE Overall, the hetastarch and plasma infusions comparably increased pCOP in healthy horses for up to 48 hours. Hetastarch induced greater, more persistent perturbations in clinicopathologic variables. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JGRA..121.1413J','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JGRA..121.1413J">Dawn-dusk asymmetries in rotating magnetospheres: Lessons from modeling Saturn</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Jia, Xianzhe; Kivelson, Margaret G. 2016-02-01 Spacecraft measurements reveal perplexing dawn-dusk asymmetries of field and plasma properties in the magnetospheres of Saturn and Jupiter. Here we describe a previously unrecognized source of dawn-dusk asymmetry in a rapidly rotating magnetosphere. We analyze two magnetohydrodynamic simulations, focusing on how flows along and across the field vary with local time in Saturn's dayside magnetosphere. As plasma rotates from dawn to noon on a dipolarizing flux tube, it flows away from the equator along the flux tube at roughly half of the sound speed (Cs), the maximum speed at which a bulk plasma can flow along a flux tube into a lower pressure region. As plasma rotates from noon to dusk on a stretching flux tube, the field-aligned component of its centripetal acceleration decreases and it flows back toward the equator at speeds typically smaller than 1/2 Cs. Correspondingly, the plasma sheet remains far thicker and the field less stretched in the afternoon than in the morning. Different radial force balance in the morning and afternoon sectors produce asymmetry in the plasma sheet thickness and a net dusk-to-dawn flow inside of L = 15 or equivalently, a large-scale electric field (E) oriented from postnoon to premidnight, as reported from observations. Morning-afternoon asymmetry analogous to that found at Saturn has been observed at Jupiter, and a noon-midnight component of E cannot be ruled out. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JGRA..122.7504D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JGRA..122.7504D">Coordinated observations of postmidnight irregularities and thermospheric neutral winds and temperatures at low latitudes</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Dao, Tam; Otsuka, Yuichi; Shiokawa, Kazuo; Nishioka, Michi; Yamamoto, Mamoru; Buhari, Suhaila M.; Abdullah, Mardina; Husin, Asnawi 2017-07-01 We investigated a postmidnight field-aligned irregularity (FAI) event observed with the Equatorial Atmosphere Radar at Kototabang (0.2°S, 100.3°E, dip latitude 10.4°S) in Indonesia on the night of 9 July 2010 using a comprehensive data set of both neutral and plasma parameters. We examined the rate of total electron content change index (ROTI) obtained from GPS receivers in Southeast Asia, airglow images detected by an all-sky imager, and thermospheric neutral winds and temperatures obtained by a Fabry-Perot interferometer at Kototabang. Altitudes of the F layer (h'F) observed by ionosondes at Kototabang, Chiang Mai, and Chumphon were also surveyed. We found that the postmidnight FAIs occurred within plasma bubbles and coincided with kilometer-scale plasma density irregularities. We also observed an enhancement of the magnetically equatorward thermospheric neutral wind at the same time as the increase of h'F at low-latitude stations, but h'F at a station near the magnetic equator remained invariant. Simultaneously, a magnetically equatorward gradient of thermospheric temperature was identified at Kototabang. The convergence of equatorward neutral winds from the Northern and Southern Hemispheres could be associated with a midnight temperature maximum occurring around the magnetic equator. Equatorward neutral winds can uplift the F layer at low latitudes and increase the growth rate of Rayleigh-Taylor instabilities, causing more rapid extension of plasma bubbles. The equatorward winds in both hemispheres also intensify the eastward Pedersen current, so a large polarization electric field generated in the plasma bubble might play an important role in the generation of postmidnight FAIs. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19304413','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19304413">Endocrine changes during pregnancy, parturition and post-partum in guanacos (Lama guanicoe).</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Riveros, José Luis; Urquieta, Bessie; Bonacic, Cristian; Hoffmann, Bernd; Bas, Fernando; Schuler, Gerhard 2009-12-01 Plasma concentrations of progesterone (P4), estradiol-17beta (E2), estrone (E1) and estrone sulfate (E1S) were measured during gestation in eight guanacos kept in captivity. Gestational length was 346.1+/-9.8 days. P4 plasma concentrations increased after ovulation and remained elevated until parturition. However, during the last 4 weeks of gestation, a gradual decrease from 4.17x1.17(+/-1)nmol/L to 2.02x1.95(+/-1)nmol/L on day 5 before parturition was observed, followed by a more abrupt final decline to baseline concentrations which were reached on the day after parturition. Mean E2 plasma concentrations started to increase during the eighth month of gestation, and were significantly elevated up to maximum concentrations of 484.7x1.21(+/-1)pmol/L during the last 2 months of pregnancy. Concentrations returned to baseline during the last 2 days of gestation. An increase of E1S concentrations (p<0.01) was observed in the eleventh month of gestation. Mean E1S concentrations remained rather constant during the last 3 weeks of gestation between 4 to 8nmol/L until parturition, when a steep precipitous decline was observed. E1 concentrations were slightly elevated during the last 4 weeks of gestation, however, maximum concentrations did not exceed 1.5nmol/L. The results show distinct species specific features of gestational steroid hormone profiles in the guanaco in comparison to domestic South American camelids, such as a more pronounced gradual prepartal decrease of P4 concentrations prior to the final decline to baseline, and clearly lesser E1S concentrations during the last 4 weeks of gestation, which lack a continuous prepartal increase. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014APS..DPPTO3012K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014APS..DPPTO3012K">Effect of Energetic Plasma Flux on Flowing Liquid Lithium Surfaces</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kalathiparambil, Kishor; Jung, Soonwook; Christenson, Michael; Fiflis, Peter; Xu, Wenyu; Szott, Mathew; Ruzic, David 2014-10-01 An operational liquid lithium system with steady state flow driven by thermo-electric magneto-hydrodynamic force and capable of constantly refreshing the plasma exposed surface have been demonstrated at U of I. To evaluate the system performance in reactor relevant conditions, specifically to understand the effect of disruptive plasma events on the performance of the liquid metal PFCs, the setup was integrated to a pulsed plasma generator. A coaxial plasma generator drives the plasma towards a theta pinch which preferentially heats the ions, simulating ELM like flux, and the plasma is further guided towards the target chamber which houses the flowing lithium system. The effect of the incident flux is examined using diagnostic tools including triple Langmuir probe, calorimeter, rogowski coils, Ion energy analyzers, and fast frame spectral image acquisition with specific optical filters. The plasma have been well characterized and a density of ~1021 m-3, with electron temperature ~10 - 20 eV is measured, and final plasma velocities of 34 - 74 kms-1 have been observed. Calorimetric measurements using planar molybdenum targets indicate a maximum plasma energy (with 6 kV plasma gun and 20 kV theta pinch) of 0.08 MJm-2 with plasma divergence effects resulting in marginal reduction of 40 +/- 23 J in plasma energy. Further results from the other diagnostic tools, using the flowing lithium targets and the planar targets coated with lithium will be presented. DOE DE-SC0008587. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013APExp...6k5102Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013APExp...6k5102Y">Low Temperature Graphene Synthesis from Poly(methyl methacrylate) Using Microwave Plasma Treatment</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Yamada, Takatoshi; Ishihara, Masatou; Hasegawa, Masataka 2013-11-01 A graphene film having low sheet resistance (600 Ω/sq.) was synthesized at low temperatures of 280 °C. Utilizing microwave plasma treatment, graphene films were synthesized from a solid phase on a copper surface. The full width at half maximum of the 2D-band in the Raman spectrum indicated that a high quality graphene film was formed. Cross-sectional transmission electron microscopy observation revealed that the deposited graphene films consisted of single- or double-layer graphene flakes of nanometer order on the Cu surface, which agrees with the estimated number of layers from an average optical transmittance of 96%. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li class="active">7</li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_8" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li class="active">8</li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="141"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013ApPhL.102o1106M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013ApPhL.102o1106M">Longitudinal terahertz wave generation from an air plasma filament induced by a femtosecond laser</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Minami, Yasuo; Kurihara, Takayuki; Yamaguchi, Keita; Nakajima, Makoto; Suemoto, Tohru 2013-04-01 We have generated and detected a longitudinally polarized (Z-polarized) terahertz (THz) wave by focusing a conically propagating THz beam generated from a plasma filament induced by a femtosecond laser pulse. In the experiment, we observed a radially polarized field in a collimated region and Z-polarized field at focus in the time domain. The maximum value of the Z-polarized THz electric field reached 1.0 kV/cm. It was also quantitatively discussed about the Z-polarized field and the radial field at the focal point. We expect this technique to find application in THz time domain spectroscopy. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015JaJAP..54fGC01M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015JaJAP..54fGC01M">High-efficiency impurity activation by precise control of cooling rate during atmospheric pressure thermal plasma jet annealing of 4H-SiC wafer</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Maruyama, Keisuke; Hanafusa, Hiroaki; Ashihara, Ryuhei; Hayashi, Shohei; Murakami, Hideki; Higashi, Seiichiro 2015-06-01 We have investigated high-temperature and rapid annealing of a silicon carbide (SiC) wafer by atmospheric pressure thermal plasma jet (TPJ) irradiation for impurity activation. To reduce the temperature gradient in the SiC wafer, a DC current preheating system and the lateral back-and-forth motion of the wafer were introduced. A maximum surface temperature of 1835 °C within 2.4 s without sample breakage was achieved, and aluminum (Al), phosphorus (P), and arsenic (As) activations in SiC were demonstrated. We have investigated precise control of heating rate (Rh) and cooling rate (Rc) during rapid annealing of P+-implanted 4H-SiC and its impact on impurity activation. No dependence of resistivity on Rh was observed, while increasing Rc significantly decreased resistivity. A minimum resistivity of 0.0025 Ω·cm and a maximum carrier concentration of 2.9 × 1020 cm-3 were obtained at Rc = 568 °C/s. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014EGUGA..16.6925E','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014EGUGA..16.6925E">Survey of the spectral properties of turbulence in the solar wind, the magnetospheres of Venus and Earth, at solar minimum and maximum</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Echim, Marius M. 2014-05-01 In the framework of the European FP7 project STORM ("Solar system plasma Turbulence: Observations, inteRmittency and Multifractals") we analyze the properties of turbulence in various regions of the solar system, for the minimum and respectively maximum of the solar activity. The main scientific objective of STORM is to advance the understanding of the turbulent energy transfer, intermittency and multifractals in space plasmas. Specific analysis methods are applied on magnetic field and plasma data provided by Ulysses, Venus Express and Cluster, as well as other solar system missions (e.g. Giotto, Cassini). In this paper we provide an overview of the spectral properties of turbulence derived from Power Spectral Densities (PSD) computed in the solar wind (from Ulysses, Cluster, Venus Express) and at the interface of planetary magnetospheres with the solar wind (from Venus Express, Cluster). Ulysses provides data in the solar wind between 1992 and 2008, out of the ecliptic, at radial distances ranging between 1.3 and 5.4 AU. We selected only those Ulysses data that satisfy a consolidated set of selection criteria able to identify "pure" fast and slow wind. We analyzed Venus Express data close to the orbital apogee, in the solar wind, at 0.72 AU, and in the Venus magnetosheath. We investigated Cluster data in the solar wind (for time intervals not affected by planetary ions effects), the magnetosheath and few crossings of other key magnetospheric regions (cusp, plasma sheet). We organize our PSD results in three solar wind data bases (one for the solar maximum, 1999-2001, two for the solar minimum, 1997-1998 and respectively, 2007-2008), and two planetary databases (one for the solar maximum, 2000-2001, that includes PSD obtained in the terrestrial magnetosphere, and one for the solar minimum, 2007-2008, that includes PSD obtained in the terrestrial and Venus magnetospheres and magnetosheaths). In addition to investigating the properties of turbulence for the minimum and maximum of the solar cycle we also analyze the spectral similarities and differences between fast and slow wind turbulence. We emphasize the importance of our data survey and analysis in the context of understanding the solar wind turbulence, the exploitation of data bases and as a first step towards developing a (virtual) laboratory for studying solar system plasma turbulence. Research supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement no 313038/STORM, and a grant of the Romanian Ministry of National Education, CNCS - UEFISCDI, project number PN-II-ID-PCE-2012-4-0418. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AnGeo..35.1219S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AnGeo..35.1219S">Unusual behavior of quiet-time zonal and vertical plasma drift velocities over Jicamarca during the recent extended solar minimum of 2008</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Santos, Ângela M.; Abdu, Mangalathayil A.; Souza, Jonas R.; Batista, Inez S.; Sobral, José H. A. 2017-11-01 The influence of the recent deep and prolonged solar minimum on the daytime zonal and vertical plasma drift velocities during quiet time is investigated in this work. Analyzing the data obtained from incoherent scatter radar from Jicamarca (11.95° S, 76.87° W) we observe an anomalous behavior of the zonal plasma drift during June 2008 characterized by lower than usual daytime westward drift and its early afternoon reversal to eastward. As a case study the zonal drift observed on 24 June 2008 is modeled using a realistic low-latitude ionosphere simulated by the Sheffield University Plasmasphere-Ionosphere Model-INPE (SUPIM-INPE). The results show that an anomalously low zonal wind was mainly responsible for the observed anomalous behavior in the zonal drift. A comparative study of the vertical plasma drifts obtained from magnetometer data for some periods of maximum (2000-2002) and minimum solar activity (1998, 2008, 2010) phases reveal a considerable decrease on the E-region conductivity and the dynamo electric field during 2008. However, we believe that the contribution of these characteristics to the unusual behavior of the zonal plasma drift is significantly smaller than that arising from the anomalously low zonal wind. The SUPIM-INPE result of the critical frequency of the F layer (foF2) over Jicamarca suggested a lower radiation flux than that predicted by solar irradiance model (SOLAR2000) for June 2008. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/20040171647','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20040171647">X-ray Observations of the Bright Old Nova V603 Aquilae</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Mukai, K.; Orio, M. 2004-01-01 We report on our Chandra and RXTE observations of the bright old nova, V603 Aql, performed in 2001 April, supplemented by our analysis of archival X-ray data on this object. We find that the RXTE data are contaminated by the Galactic Ridge X-ray emission. After accounting for this effect, we find a high level of aperiodic variability in the RXTE data, at a level consistent with the uncontaminated Chandra data. The Chandra HETG spectrum clearly originates in a multi-temperature plasma. We constrain the possible emission measure distribution of the plasma through a combination of global and local fits. The X-ray luminosity and the spectral shape of V603 Aql resemble those of SS Cyg in transition between quiescence and outburst. The fact that the X-ray flux variability is only weakly energy dependent can be interpreted by supposing that the variability is due to changes in the maximum temperature of the plasma. The plasma density is likely to be high, and the emission region is likely to be compact. Finally, the apparent overabundance of Ne is consistent with V603 Aql being a young system. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016P%26SS..130...60S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016P%26SS..130...60S">Ion energy distributions and densities in the plume of Enceladus</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Sakai, Shotaro; Cravens, Thomas E.; Omidi, Nojan; Perry, Mark E.; Waite, J. Hunter 2016-10-01 Enceladus has a dynamic plume that is emitting gas, including water vapor, and dust. The gas is ionized by solar EUV radiation, charge exchange, and electron impact and extends throughout the inner magnetosphere of Saturn. The charge exchange collisions alter the plasma composition. Ice grains (dust) escape from the vicinity of Enceladus and form the E ring, including a portion that is negatively charged by the local plasma. The inner magnetosphere within 10 RS (Saturn radii) contains a complex mixture of plasma, neutral gas, and dust that links back to Enceladus. In this paper we investigate the energy distributions, ion species and densities of water group ions in the plume of Enceladus using test particle and Monte Carlo methods that include collisional processes such as charge exchange and ion-neutral chemical reactions. Ion observations from the Cassini Ion and Neutral Mass Spectrometer (INMS) for E07 are presented for the first time. We use the modeling results to interpret observations made by the Cassini Plasma Spectrometer (CAPS) and the INMS. The low energy ions, as observed by CAPS, appear to be affected by a vertical electric field (EZ=-10 μV/m) in the plume. The EZ field may be associated with the charged dust and/or the pressure gradient of plasma. The model results, along with the results of earlier models, show that H3O+ ions created by chemistry are predominant in the plume, which agrees with INMS and CAPS data, but the INMS count rate in the plume for the model is several times greater than the data, which we do not fully understand. This composition and the total ion count found in the plume agree with INMS and CAPS data. On the other hand, the Cassini Langmuir Probe measured a maximum plume ion density more than 30,000 cm-3, which is far larger than the maximum ion density from our model, 900 cm-3. The model results also demonstrate that most of the ions in the plume are from the external magnetospheric flow and are not generated by local ionization. The origin of the ions in the plume was investigated using two different velocity models. Most ions were created by the interaction with background magnetospheric plasma and by photoionization. INMS and CAPS also detected water cluster ions. We will interpret these observations as a result of ion collisions with neutral water clusters, (H2O)n, originating in the tiger stripe vents as suggested by Tokar et al. (2009). We also estimated the process of generating cluster ions based on the INMS observations. We suggest that the most likely source is reaction of H3O+ with neutral water clusters or dimers such as (H2O)2 formed in the plume vents. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017Ap%26SS.362...93K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017Ap%26SS.362...93K">Morphology of equatorial plasma bubbles during low and high solar activity years over Indian sector</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kumar, Sanjay 2017-05-01 In the present study, slant total electron content (STEC) data computed from ground based GPS measurements over Hyderabad (Geog. Lat. 17.41° N, geog. long. 78.55° E, mag. lat. 08.81° N) and two close stations at Bangalore (Geog. Lat. 13.02°/13.03° N, geog. long. 77.57°/77.51° E, mag. lat. 04.53°/04.55° N) in Indian region during 2007-2012, have been used to study the occurrences and characteristics of equatorial plasma bubbles (EPBs). The analysis found maximum EPB occurrences during the equinoctial months and minimum during the December solstice throughout 2007-2012 except during the solar minimum years in 2007-2009. During 2007-2009, the maximum EPB occurrences were observed in June solstice which could not be predicted by the model proposed by Tsunoda (J. Geophys. Res., 90:447-456, 1985). The equinox maximum in EPB occurrences for high solar activity years could be caused by the vertical F-layer drift due to pre-reversal electric field (PRE), and expected to be maximum when day-night terminator aligns with the magnetic meridian i.e. during the equinox months whereas maximum occurrences during the solstice months of solar minimum could be caused by the seed perturbation in plasma density induced by gravity waves from tropospheric origins. Generally EPB occurrences are found to be more prominent during nighttime hours (2000-2400 hours) than the daytime hours. Peak in EPB occurrences is in early night for high solar activity years whereas same is late night for low solar activity. The day and nighttime EPB occurrences have been analyzed and found to vary in accordance with solar activity with an annual correlation coefficient (R) of ˜0.99 with F_{10.7} cm solar Flux. Additionally, solar activity influence on EPB occurrences is seasonal dependent with a maximum influence during the equinox season (R=0.88) and a minimum during winter season (R =0.73). The solar activity influences on EPB occurrences are found in agreement with the previous works reported in the Brazilian, African-Asian and Pacific longitudes sector but different than that in Atlantic sector. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/17411231','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/17411231">Development of a liquid tin microjet target for an efficient laser-produced plasma extreme ultraviolet source.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Higashiguchi, Takeshi; Hamada, Masaya; Kubodera, Shoichi 2007-03-01 A regenerative tin liquid microjet target was developed for a high average power extreme ultraviolet (EUV) source. The diameter of the target was smaller than 160 microm and good vacuum lower than 0.5 Pa was maintained during the operation. A maximum EUV conversion efficiency of 1.8% at the Nd:yttrium-aluminum-garnet laser intensity of around 2 x 10(11) Wcm(2) with a spot diameter of 175 microm (full width at half maximum) was observed. The angular distribution of the EUV emission remained almost isotropic, whereas suprathermal ions mainly emerged toward the target normal. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2007RScI...78c6106H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2007RScI...78c6106H">Development of a liquid tin microjet target for an efficient laser-produced plasma extreme ultraviolet source</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Higashiguchi, Takeshi; Hamada, Masaya; Kubodera, Shoichi 2007-03-01 A regenerative tin liquid microjet target was developed for a high average power extreme ultraviolet (EUV) source. The diameter of the target was smaller than 160 μm and good vacuum lower than 0.5 Pa was maintained during the operation. A maximum EUV conversion efficiency of 1.8% at the Nd:yttrium-aluminum-garnet laser intensity of around 2×1011 W/cm2 with a spot diameter of 175 μm (full width at half maximum) was observed. The angular distribution of the EUV emission remained almost isotropic, whereas suprathermal ions mainly emerged toward the target normal. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AGUFMSM51A2530B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AGUFMSM51A2530B">Velocity Space Evolution of Dayside Reconnection Outflow</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Broll, J. M.; Fuselier, S. A.; Trattner, K. J. 2015-12-01 Magnetic reconnection is a universal phenomenon occurring when energy stored in a complicated magnetic field topology is released into the surrounding plasma as the field simplifies its configuration. At Earth's dayside magnetopause, reconnection is responsible for mass and energy input from the solar wind into the magnetosphere. We describe the evolution of the velocity-space evolution of plasma outflow from a dayside magnetic reconnection region. We analyze Cluster magnetopause crossings between 1 and 10 Earth radii from the reconnection X-line predicted by the maximum magnetic shear model. The effects of nonadiabatic processes, such as deformation of the profile due to finite-gyroradius-induced pitch-angle scattering and wave-particle interactions, are described. We compare observations and simulation results to describe the outflow evolution and infer the field-aligned distance between an observation and the reconnection site producing it. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017NucFu..57l6032T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017NucFu..57l6032T">Numerical modeling of lower hybrid current drive in fully non-inductive plasma start-up experiments on TST-2</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Tsujii, N.; Takase, Y.; Ejiri, A.; Shinya, T.; Togashi, H.; Yajima, S.; Yamazaki, H.; Moeller, C. P.; Roidl, B.; Sonehara, M.; Takahashi, W.; Toida, K.; Yoshida, Y. 2017-12-01 Non-inductive plasma start-up is a critical issue for spherical tokamaks since there is not enough room to provide neutron shielding for the center solenoid. Start-up using lower hybrid (LH) waves has been studied on the TST-2 spherical tokamak. Because of the low magnetic field of a spherical tokamak, the plasma density needs to be kept at a very low value during the plasma current ramp-up so that the plasma core remains accessible to the LH waves. However, we have found that higher density was required to sustain larger plasma current. The achievable plasma current was limited by the maximum operational toroidal field of TST-2. The existence of an optimum density for LH current drive and its toroidal field dependence is explained through a numerical simulation based on a ray tracing code and a Fokker-Planck solver. In order to access higher density at the same magnetic field, a top-launch antenna was recently installed in addition to the existing outboard-launch antenna. Increase in the density limit was observed when the power was launched from the top antenna, consistently with the numerical predictions. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19428944','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19428944">Studies on distribution and metabolism of para-methoxymethamphetamine (PMMA) in rats after subcutaneous administration.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Rohanova, Miroslava; Balikova, Marie 2009-05-02 p-Methoxymethamphetamine (PMMA) is an illegal psychedelic drug of abuse derived from an amphetamine structure with a risk to health and reports of several cases of intoxications and fatalities caused by its ingestion. However, its pharmacokinetics based on a controlled study is unknown and only partial information on its biotransformation in animal models is available. Our experimental design aimed to study the disposition and kinetic profile of PMMA and its metabolites in rat plasma and selected tissues after the bolus subcutaneous dose of 40mg/kg, using a GC-MS method. Prior to this, we performed a qualitative verification of its metabolites appearing in excreted urine fractions. PMMA maximum plasma concentration of 4014+/-1122ng/mL was reached 30min after dosing, whereas the appearance of metabolites was rather delayed. The disposition of PMMA was characterized by its approximate half-life of 1.0h, volume of distribution of 6.4L/kg and plasma clearance of 4.4L/h. PMMA tissue concentration exceeded plasma and the highest one was found in the lungs (c(max) 42,988+/-10,223ng/g). Penetration through the blood/brain barrier was more efficient considering PMMA and its N-desmethylated metabolite PMA (para-methoxyamphetamine) than hydroxylated metabolites. The maximum brain/plasma ratio value of PMMA (15.8) and PMA (11.8) was reached after 8h of observation. The experimental results ascertained could be useful for subsequent evaluation of the psychotropic or neurotoxic effects of PMMA and for diagnostic concern of intoxication. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018ApJ...855L..16J','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018ApJ...855L..16J">An Observationally Constrained Model of a Flux Rope that Formed in the Solar Corona</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> James, Alexander W.; Valori, Gherardo; Green, Lucie M.; Liu, Yang; Cheung, Mark C. M.; Guo, Yang; van Driel-Gesztelyi, Lidia 2018-03-01 Coronal mass ejections (CMEs) are large-scale eruptions of plasma from the coronae of stars. Understanding the plasma processes involved in CME initiation has applications for space weather forecasting and laboratory plasma experiments. James et al. used extreme-ultraviolet (EUV) observations to conclude that a magnetic flux rope formed in the solar corona above NOAA Active Region 11504 before it erupted on 2012 June 14 (SOL2012-06-14). In this work, we use data from the Solar Dynamics Observatory (SDO) to model the coronal magnetic field of the active region one hour prior to eruption using a nonlinear force-free field extrapolation, and find a flux rope reaching a maximum height of 150 Mm above the photosphere. Estimations of the average twist of the strongly asymmetric extrapolated flux rope are between 1.35 and 1.88 turns, depending on the choice of axis, although the erupting structure was not observed to kink. The decay index near the apex of the axis of the extrapolated flux rope is comparable to typical critical values required for the onset of the torus instability, so we suggest that the torus instability drove the eruption. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016PPCF...58d5028S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016PPCF...58d5028S">Isotope effects of trapped electron modes in the presence of impurities in tokamak plasmas</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Shen, Yong; Dong, J. Q.; Sun, A. P.; Qu, H. P.; Lu, G. M.; He, Z. X.; He, H. D.; Wang, L. F. 2016-04-01 The trapped electron modes (TEMs) are numerically investigated in toroidal magnetized hydrogen, deuterium and tritium plasmas, taking into account the effects of impurity ions such as carbon, oxygen, helium, tungsten and others with positive and negative density gradients with the rigorous integral eigenmode equation. The effects of impurity ions on TEMs are investigated in detail. It is shown that impurity ions have substantially-destabilizing (stabilizing) effects on TEMs in isotope plasmas for {{L}ez}\\equiv {{L}ne}/{{L}nz}>0 (<0 ), opposite to the case of ion temperature gradient (ITG) driven modes. Detailed analyses of the isotope mass dependence for TEM turbulences in hydrogenic isotope plasmas with and without impurities are performed. The relations between the maximum growth rate of the TEMs with respect to the poloidal wave number and the ion mass number are given in the presence of the impurity ions. The results demonstrate that the maximum growth rates scale as {γ\\max}\\propto Mi-0.5 in pure hydrogenic plasmas. The scale depends on the sign of its density gradient and charge number when there is a second species of (impurity) ions. When impurity ions have density profiles peaking inwardly (i.e. {{L}ez}\\equiv {{L}ne}/{{L}nz}>0 ), the scaling also depends on ITG parameter {ηi} . The maximum growth rates scale as {γ\\max}\\propto M\\text{eff}-0.5 for the case without ITG ({ηi}=0 ) or the ITG parameter is positive ({ηi}>0 ) but the impurity ion charge number is low (Z≤slant 5.0 ). However, when {ηi}>0 and the impurity ion charge number is moderate (Z=6.0-8.0 ), the scaling law is found as {γ\\max}\\propto M\\text{eff}-1.0 . Here, Z is impurity ion charge number, and the effective mass number, {{M}\\text{eff}}=≤ft(1-{{f}z}\\right){{M}i}+{{f}z}{{M}z} , with {{M}i} and {{M}Z} being the mass numbers of the hydrogenic and impurity ions, respectively, and {{f}z}=Z{{n}0z}/{{n}0e} being the charge concentration of impurity ions. In addition, with regard to the case of {{L}ez}<0 , the maximum growth rate scaling is {γ\\max}\\propto Mi-0.5 . The possible relations of the results with experimental observations are discussed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JGRA..123.1583S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JGRA..123.1583S">The Plasma Environment Associated With Equatorial Ionospheric Irregularities</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Smith, Jonathon M.; Heelis, R. A. 2018-02-01 We examine the density structure of equatorial depletions referred to here as equatorial plasma bubbles (EPBs). Data recorded by the Ion Velocity Meter as part of the Coupled Ion Neutral Dynamics Investigation (CINDI) aboard the Communication/Navigation Outage Forecasting System (C/NOFS) satellite are used to study EPBs from 1600 to 0600 h local time at altitudes from 350 to 850 km. The data are taken during the 7 years from 2008 to 2014, more than one half of a magnetic solar cycle, that include solar minimum and a moderate solar maximum. Using a rolling ball algorithm, EPBs are identified by profiles in the plasma density, each having a depth measured as the percent change between the background and minimum density (ΔN/N). During solar moderate activity bubbles observed in the topside postsunset sector are more likely to have large depths compared to those observed in the topside postmidnight sector. Large bubble depths can be observed near 350 km in the bottomside F region in the postsunset period. Conversely at solar minimum the distribution of depths is similar in the postsunset and postmidnight sectors in all longitude sectors. Deep bubbles are rarely observed in the topside postsunset sector and never in the bottomside above 400 km in altitude. We suggest that these features result from the vertical drift of the plasma for these two solar activity levels. These drift conditions affect both the background density in which bubbles are embedded and the growth rate of perturbations in the bottomside where bubbles originate. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22043368-direct-thrust-measurements-modelling-radio-frequency-expanding-plasma-thruster','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22043368-direct-thrust-measurements-modelling-radio-frequency-expanding-plasma-thruster">Direct thrust measurements and modelling of a radio-frequency expanding plasma thruster</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Lafleur, T.; Charles, C.; Boswell, R. W. 2011-08-15 It is shown analytically that the thrust from a simple plasma thruster (in the absence of a magnetic field) is given by the maximum upstream electron pressure, even if the plasma diverges downstream. Direct thrust measurements of a thruster are then performed using a pendulum thrust balance and a laser displacement sensor. A maximum thrust of about 2 mN is obtained at 700 W for a thruster length of 17.5 cm and a flow rate of 0.9 mg s{sup -1}, while a larger thrust of 4 mN is obtained at a similar power for a length of 9.5 cm andmore » a flow rate of 1.65 mg s{sup -1}. The measured thrusts are in good agreement with the maximum upstream electron pressure found from measurements of the plasma parameters and in fair agreement with a simple global approach used to model the thruster.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017PhPl...24g3504G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017PhPl...24g3504G">Theoretical modeling to study the impact of different oxidizers (etchants) on the plasma-assisted catalytic carbon nanofiber growth</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Gupta, Ravi; Sharma, Suresh C. 2017-07-01 An analytical model based on the various surface deposition processes and plasma sheath kinetics of the plasma species (electrons, positively charged ions, radicals, and neutrals) has been developed to investigate the effects of different plasmas (different etchants) on the catalyzed plasma aided growth of carbon nanofibers (CNFs). In particular, the model accounts the poisoning of the catalyst nanoparticle, i.e., the formation of the amorphous carbon layer on the catalyst active surface due to the continuous dissociation of incoming hydrocarbon species from the plasma. It is observed that oxidizers (H2O and O2) in the typical hydrocarbon/hydrogen (C2H2 + H2) plasma act as the dominant etchants and remove the amorphous carbon layer from the catalyst surface and, thus, preserve and enhance the catalyst activity. However, the growth rate of CNFs is much higher when O2 is added as an etchant in the reactive plasma as compared to H2O. This is due to the dual role played by the oxygen, i.e., (i) removal of amorphous carbon from the catalyst active surface, (ii) removal of hydrogen radicals that interact with the carbon species generated on the catalyst surface and suppress their diffusion through the catalyst nanoparticles. The CNF grows much longer in the presence of O2, therefore, etching of CNF tip and deformation of catalyst nanoparticle is the maximum, and hence, the CNF tip diameter is least. Moreover, in the present investigation, we also found that the relative concentrations of H2O or O2 species in the reactive plasma have significant effects on the CNF growth. Our theoretical results are in good agreement with the experimental observations. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JaJAP..57aAF06S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JaJAP..57aAF06S">Properties of spray-deposited liquid-phase exfoliated graphene films</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Sales, Maria Gabriela C.; Dela Vega, Ma. Shanlene D. C.; Vasquez, Magdaleno R., Jr. 2018-01-01 In this study, we demonstrate the feasibility of spray-depositing exfoliated graphene on flexible polyimide (PI) and rigid (soda lime glass) substrates for optoelectronic applications. The water contact angles of the substrates increased by 13% (for PI) and 49% (for glass) when the surfaces are pretreated with hexamethyldisiloxane, which significantly improved the adhesion of the films. Raman spectral analyses confirmed a minimum of 15 and a maximum of 23 layers of exfoliated graphene deposited on the substrates. After deposition, the films were exposed to 13.56 MHz radio-frequency plasma containing an admixture of argon and nitrogen gases. Plasma treatment modified the electrical properties with a response analogous to that of a rectifier. A 39% increase in transmittance in the visible region was also observed especially for glass substrates after plasma treatment without a significant change in film electrical conductivity. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014PhDT.......103C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014PhDT.......103C">Density and beta limits in the Madison Symmetric Torus Reversed-Field Pinch</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Caspary, Kyle Jonathan Operational limits and the underlying physics are explored on the Madison Symmetric Torus (MST) Reversed-Field Pinch (RFP) using deuterium pellet fueling. The injection of a fast pellet provides a large source of fuel in the plasma edge upon impact with the vessel wall, capable of triggering density limit terminations for the full range of plasma current, up to 600 kA. As the pellet size and plasma density increase, approaching the empirical Greenwald limit, plasma degradation is observed in the form of current decay, increased magnetic activity in the edge and core, increased radiation and plasma cooling. The complete termination of the plasma is consistent with the Greenwald limit; however, a slightly smaller maximum density is observed in discharges without toroidal field reversal. The plasma beta is the ratio of the plasma pressure to the confining magnetic pressure. Beta limits are known to constrain other magnetic confinement devices, but no beta limit has yet been established on the RFP. On MST, the highest beta values are obtained in improved confinement discharges with pellet fueling. By using pellet injection to scan the plasma density during PPCD, we also achieve a scan of Ohmic input power due to the increase in plasma resistivity. We observe a factor of 3 or more increase in Ohmic power as we increase the density from 1*1019 to 3*10 19 m-3. Despite this increased Ohmic power, the electron contribution to beta is constant, suggesting a confinement limited beta for the RFP. The electrons and ions are classically well coupled in these cold, dense pellet fueled plasmas, so the increase in total beta at higher density is primarily due to the increased ion contribution. The interaction of pellet fueling and NBI heating is explored. Modeling of MST's neutral heating beam suggests an optimal density for beam power deposition of 2-3*1019 m-3. Low current, NBI heated discharges show evidence of an increased electron beta in this density range. Additionally, the fast ion population can enhance ablation as well as cause pellet deflection. Other exploratory experiments with the pellet injection system explore additional injection scenarios and expand the injector capabilities. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015JGRA..120..344D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015JGRA..120..344D">Upstream proton cyclotron waves at Venus near solar maximum</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Delva, M.; Bertucci, C.; Volwerk, M.; Lundin, R.; Mazelle, C.; Romanelli, N. 2015-01-01 magnetometer data of Venus Express are analyzed for the occurrence of waves at the proton cyclotron frequency in the spacecraft frame in the upstream region of Venus, for conditions of rising solar activity. The data of two Venus years up to the time of highest sunspot number so far (1 Mar 2011 to 31 May 2012) are studied to reveal the properties of the waves and the interplanetary magnetic field (IMF) conditions under which they are observed. In general, waves generated by newborn protons from exospheric hydrogen are observed under quasi- (anti)parallel conditions of the IMF and the solar wind velocity, as is expected from theoretical models. The present study near solar maximum finds significantly more waves than a previous study for solar minimum, with an asymmetry in the wave occurrence, i.e., mainly under antiparallel conditions. The plasma data from the Analyzer of Space Plasmas and Energetic Atoms instrument aboard Venus Express enable analysis of the background solar wind conditions. The prevalence of waves for IMF in direction toward the Sun is related to the stronger southward tilt of the heliospheric current sheet for the rising phase of Solar Cycle 24, i.e., the "bashful ballerina" is responsible for asymmetric background solar wind conditions. The increase of the number of wave occurrences may be explained by a significant increase in the relative density of planetary protons with respect to the solar wind background. An exceptionally low solar wind proton density is observed during the rising phase of Solar Cycle 24. At the same time, higher EUV increases the ionization in the Venus exosphere, resulting in higher supply of energy from a higher number of newborn protons to the wave. We conclude that in addition to quasi- (anti)parallel conditions of the IMF and the solar wind velocity direction, the higher relative density of Venus exospheric protons with respect to the background solar wind proton density is the key parameter for the higher number of observable proton cyclotron waves near solar maximum. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li class="active">8</li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_9" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li class="active">9</li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="161"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5113768','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5113768">Extended‐Release Once‐Daily Formulation of Tofacitinib: Evaluation of Pharmacokinetics Compared With Immediate‐Release Tofacitinib and Impact of Food</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Wang, Rong; Fletcher, Tracey; Alvey, Christine; Kushner, Joseph; Stock, Thomas C. 2016-01-01 Abstract Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis. An extended‐release (XR) formulation has been designed to provide a once‐daily (QD) dosing option to patients to achieve comparable pharmacokinetic (PK) parameters to the twice‐daily immediate‐release (IR) formulation. We conducted 2 randomized, open‐label, phase 1 studies in healthy volunteers. Study A characterized single‐dose and steady‐state PK of tofacitinib XR 11 mg QD and intended to demonstrate equivalence of exposure under single‐dose and steady‐state conditions to tofacitinib IR 5 mg twice daily. Study B assessed the effect of a high‐fat meal on the bioavailability of tofacitinib from the XR formulation. Safety and tolerability were monitored in both studies. In study A (N = 24), the XR and IR formulations achieved time to maximum plasma concentration at 4 hours and 0.5 hours postdose, respectively; terminal half‐life was 5.9 hours and 3.2 hours, respectively. Area under plasma concentration‐time curve (AUC) and maximum plasma concentration (Cmax) after single‐ and multiple‐dose administration were equivalent between the XR and IR formulations. In study B (N = 24), no difference in AUC was observed for fed vs fasted conditions. Cmax increased by 27% under the fed state. On repeat administration, negligible accumulation (<20%) of systemic exposures was observed for both formulations. Steady state was achieved within 48 hours of dosing with the XR formulation. Tofacitinib administration as an XR or IR formulation was generally well tolerated in these studies. PMID:26970526 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5300148','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5300148">Viability of primary osteoblasts after treatment with tenofovir alafenamide: Lack of cytotoxicity at clinically relevant drug concentrations</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Callebaut, Christian; Liu, Yang; Babusis, Darius; Ray, Adrian; Miller, Michael; Kitrinos, Kathryn 2017-01-01 Tenofovir alafenamide (TAF) is a phosphonoamidate prodrug of the nucleotide HIV reverse transcriptase inhibitor tenofovir (TFV). TAF is approved for the treatment of HIV-1 infection as part of the single-tablet regimen containing elvitegravir, cobicistat, emtricitabine, and TAF. When dosed once-daily, TAF results in approximately 90% lower levels of plasma TFV and a 4-fold increase in intracellular TFV-diphosphate (TFV-DP) in PBMCs compared with the TFV prodrug tenofovir disoproxil fumarate (TDF). Several antiretrovirals, including TDF, have been associated with bone mineral density decreases in patients; the effect of clinically relevant TAF concentrations on primary osteoblast viability was therefore assessed in vitro. Studies in PBMCs determined that a 2-hour TAF exposure at concentrations similar to human plasma Cmax achieved intracellular TFV-DP levels comparable to those observed after the maximum recommended human dose of 25 mg TAF. Comparable intracellular TFV-DP levels were achieved in primary osteoblasts with 2-hour TAF exposure daily for 3 days at concentrations similar to those used for PBMCs (100–400 nM). No change in cell viability was observed in either primary osteoblasts or PBMCs. The mean TAF CC50 in primary osteoblasts after 3 days of daily 2-hour pulses was >500 μM, which is >1033 times higher than the TAF maximum recommended human dose plasma Cmax. In summary, primary osteoblasts were not preferentially loaded by TAF compared with PBMCs, with comparable TFV-DP levels achieved in both cell types. Furthermore, there was no impact on osteoblast cell viability at clinically relevant TAF concentrations. PMID:28182625 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28182625','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28182625">Viability of primary osteoblasts after treatment with tenofovir alafenamide: Lack of cytotoxicity at clinically relevant drug concentrations.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Callebaut, Christian; Liu, Yang; Babusis, Darius; Ray, Adrian; Miller, Michael; Kitrinos, Kathryn 2017-01-01 Tenofovir alafenamide (TAF) is a phosphonoamidate prodrug of the nucleotide HIV reverse transcriptase inhibitor tenofovir (TFV). TAF is approved for the treatment of HIV-1 infection as part of the single-tablet regimen containing elvitegravir, cobicistat, emtricitabine, and TAF. When dosed once-daily, TAF results in approximately 90% lower levels of plasma TFV and a 4-fold increase in intracellular TFV-diphosphate (TFV-DP) in PBMCs compared with the TFV prodrug tenofovir disoproxil fumarate (TDF). Several antiretrovirals, including TDF, have been associated with bone mineral density decreases in patients; the effect of clinically relevant TAF concentrations on primary osteoblast viability was therefore assessed in vitro. Studies in PBMCs determined that a 2-hour TAF exposure at concentrations similar to human plasma Cmax achieved intracellular TFV-DP levels comparable to those observed after the maximum recommended human dose of 25 mg TAF. Comparable intracellular TFV-DP levels were achieved in primary osteoblasts with 2-hour TAF exposure daily for 3 days at concentrations similar to those used for PBMCs (100-400 nM). No change in cell viability was observed in either primary osteoblasts or PBMCs. The mean TAF CC50 in primary osteoblasts after 3 days of daily 2-hour pulses was >500 μM, which is >1033 times higher than the TAF maximum recommended human dose plasma Cmax. In summary, primary osteoblasts were not preferentially loaded by TAF compared with PBMCs, with comparable TFV-DP levels achieved in both cell types. Furthermore, there was no impact on osteoblast cell viability at clinically relevant TAF concentrations. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017ApPhA.123..223A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017ApPhA.123..223A">Growth of surface structures correlated with structural and mechanical modifications of brass by laser-induced Si plasma ions implantation</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Ahmad, Shahbaz; Bashir, Shazia; Rafique, M. Shahid; Yousaf, Daniel 2017-04-01 Laser-produced Si plasma is employed as an ion source for implantation on the brass substrate for its surface, structural, and mechanical modifications. Thomson parabola technique is employed for the measurement of energy and flux of Si ions using CR-39. In response to stepwise increase in number of laser pulses from 3000 to 12000, four brass substrates were implanted by laser-induced Si plasma ions of energy 290 keV at different fluxes ranging from 45 × 1012 to 75 × 1015 ions/cm2. SEM analysis reveals the formation of nano/micro-sized irregular shaped cavities and pores for the various ion fluxes for varying numbers of laser pulses from 3000 to 9000. At the maximum ion flux for 12,000 pulses, distinct and organized grains with hexagonal and irregular shaped morphology are revealed. X-ray diffractometer (XRD) analysis exhibits that a new phase of CuSi (311) is identified which confirms the implantation of Si ions in brass substrate. A significant decrease in mechanical properties of implanted brass, such as Yield Stress (YS), Ultimate Tensile Strength (UTS), and hardness, with increasing laser pulses from 3000 to 6000 is observed. However, with increasing laser pulses from 9000 to a maximum value of 12,000, an increase in mechanical properties like hardness, YS, and UTS is observed. The generation as well as annihilation of defects, recrystallization, and intermixing of Si precipitates with brass matrix is considered to be responsible for variations in surface, structural, and mechanical modifications of brass. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28343290','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28343290">Muscle Injury After Intramuscular Administration of Diclofenac: A Case Report Supported by Magnetic Resonance Imaging.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Probst, Mareike; Kühn, Jens-Peter; Modeß, Christiane; Scheuch, Eberhard; Seidlitz, Anne; Hosten, Norbert; Siegmund, Werner; Weitschies, Werner 2017-12-01 Intramuscular injection of diclofenac is still frequently practiced, although there is ample evidence that the risk of local tissue intolerability is highly underestimated. The aim of this study was to evaluate local toxicity in a patient using magnetic resonance imaging. A patient who gave written informed consent received a medically indicated intramuscular administration of diclofenac 75 mg/2 mL. Simultaneously with magnetic resonance imaging of the depot, a clinical-chemical evaluation and quantification of diclofenac in plasma was performed. A manifold enhancement of the T2-weighted magnetic resonance signal was observed in a muscle area of approximately 60 mL volume, with maximum signal intensity 30 min after injection, the time of maximum diclofenac plasma exposure. Plasma creatine kinase activity was elevated approximately sixfold within 8 h and normalized within 1 week, whereas the magnetic resonance enhancement disappeared within 5 weeks. Interestingly, the patient did not complain about any clinical symptoms at the injection site. Asymptomatic tissue injury after intramuscular injection of diclofenac, caused by intramuscular dosing, can be reliably evaluated by magnetic resonance imaging and should be applied early during the development of parenteral dosage forms. Clinical Trials Registration Number: BB130/16 (Ethics Committee of the University Medicine Greifswald). </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19252346','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19252346">Pioglitazone metabolic effect in metformin-intolerant obese patients treated with sibutramine.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Derosa, Giuseppe; Mereu, Roberto; Salvadeo, Sibilla A T; D'Angelo, Angela; Ciccarelli, Leonardina; Piccinni, Mario N; Ferrari, Ilaria; Gravina, Alessia; Maffioli, Pamela; Cicero, Arrigo F G 2009-01-01 Metformin is the drug of choice to treat obese type 2 diabetes patients because it reduces either insulin-resistance and body weight. We aimed to comparatively test the efficacy and tolerability of pioglitazone and sibutramine in metformin-intolerant obese type 2 diabetic patients treated with sibutramine. Five hundred and seventy-six consecutive Caucasian obese type 2 diabetic patients were evaluated during a 12-months period and fifty-two patients were resulted intolerant to metformin at maximum dosage (3,000 mg/day). All intolerant patients to metformin received a treatment with pioglitazone (45 mg/day) and sibutramine (10 mg/day) and they were compared with fifty-three patients treated with metformin (3,000 mg/day) and sibutramine (10 mg/day) for 6 months in a single-blind controlled trial. We assessed body mass index, waist circumference, glycated hemoglobin, Fasting Plasma glucose, postprandial plasma glucose, fasting plasma insulin, postprandial plasma insulin, lipid profile, systolic blood pressure, diastolic blood pressure and heart rate at baseline and after 3, and 6 months. No body mass index change was observed at 3, and 6 months in pioglitazone + sibutramine group, while a significant reduction of body mass index and waist circumference was observed after 6 months in metformin + sibutramine group (p<0.05). A significant decrease of glycated hemoglobin, Fasting Plasma glucose, postprandial plasma glucose, fasting plasma insulin, postprandial plasma insulin and HOMA index was observed after 3, and 6 months in both groups (p<0.05, and p<0.01, respectively). A significant Tg reduction was present after 6 months (p<0.05) in both groups respect to the baseline values. No systolic blood pressure, diastolic blood pressure and heart rate change was obtained after 3, and 6 months in both groups. Pioglitazone and sibutramine combination appears to be a short-term equally efficacious and well-tolerated therapeutic alternative respect to metformin-intolerant obese type 2 diabetic patients treated with sibutramine. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25741748','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25741748">Optical Emission Studies of Copper Plasma Induced Using Infrared Transversely Excited Atmospheric (IR TEA) Carbon Dioxide Laser Pulses.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Momcilovic, Milos; Kuzmanovic, Miroslav; Rankovic, Dragan; Ciganovic, Jovan; Stoiljkovic, Milovan; Savovic, Jelena; Trtica, Milan 2015-04-01 Spatially resolved, time-integrated optical emission spectroscopy was applied for investigation of copper plasma produced by a nanosecond infrared (IR) transversely excited atmospheric (TEA) CO2 laser, operating at 10.6 μm. The effect of surrounding air pressure, in the pressure range 0.1 to 1013 mbar, on plasma formation and its characteristics was investigated. A linear dependence of intensity threshold for plasma formation on logarithm of air pressure was found. Lowering of the air pressure reduces the extent of gas breakdown, enabling better laser-target coupling and thus increases ablation. Optimum air pressure for target plasma formation was 0.1 mbar. Under that pressure, the induced plasma consisted of two clearly distinguished and spatially separated regions. The maximum intensity of emission, with sharp and well-resolved spectral lines and negligibly low background emission, was obtained from a plasma zone 8 mm from the target surface. The estimated excitation temperature in this zone was around 7000 K. The favorable signal to background ratio obtained in this plasma region indicates possible analytical application of TEA CO2 laser produced copper plasma. Detection limits of trace elements present in the Cu sample were on the order of 10 ppm (parts per million). Time-resolved measurements of spatially selected plasma zones were used to find a correlation between the observed spatial position and time delay. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22364918-plasma-flows-voyager-away-from-measured-suprathermal-pressures','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22364918-plasma-flows-voyager-away-from-measured-suprathermal-pressures">PLASMA FLOWS AT VOYAGER 2 AWAY FROM THE MEASURED SUPRATHERMAL PRESSURES</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> McComas, D. J.; Schwadron, N. A., E-mail: dmccomas@swri.edu 2014-11-01 Plasma flows measured by Voyager 2 show a clear rotation away from radially outward with increasing penetration into the inner heliosheath while the overall flow speed remains roughly constant. However, the direction of rotation is far more into the transverse, and less into the polar direction, than predicted. No current model reproduces the key observational results of (1) the direction of flow rotation or (2) constancy of the flow speed. Here we show that the direction is consistent with flow away from the region of maximum pressure in the inner heliosheath, ∼20° south of the upwind direction, as measured bymore » the Interstellar Boundary Explorer (IBEX). Further, we show that the dominance of the suprathermal ion pressure in the inner heliosheath measured by IBEX can explain both the observed flow rotation and constancy of the flow speed. These results indicate the critical importance of suprathermal ions in the physics of the inner heliosheath and have significant implications for understanding this key region of the heliosphere's interstellar interaction and astrophysical plasmas more broadly.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/538465-anomalous-width-variations-ion-acoustic-rarefactive-solitary-waves-warm-ion-plasma-two-electron-temperatures','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/538465-anomalous-width-variations-ion-acoustic-rarefactive-solitary-waves-warm-ion-plasma-two-electron-temperatures">Anomalous width variations for ion acoustic rarefactive solitary waves in a warm ion plasma with two electron temperatures</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Ghosh, S.S.; Sekar Iyengar, A.N. 1997-09-01 Anomalous width{endash}amplitude variations were observed in large amplitude rarefactive solitary waves which show increasing width with increasing amplitude, contrasting the usual reciprocal relation between the square of the width and the amplitude, beyond a certain value of the plasma parameters [S. S. Ghosh, K. K. Ghosh, and A. N. Sekar Iyengar, Phys. Plasmas, {bold 3}, 3939 (1996)]. For the limiting maximum amplitude, the {open_quotes}increasing width{close_quotes} solitary wave tends to a double layer-like solution. The overall variation was found to depend crucially on the specific parameter space. From a detailed investigation of the above behavior, a plausible physical explanation has beenmore » presented for such increases in the width. It is found that the ions{close_quote} initial kinetic energies and the cold electron concentration within the perturbed region play a significant role in determining the observed width{endash}amplitude variation. This contradicts the investigation of Sayal, Yadav, and Sharma [Phys. Scr. {bold 47}, 576 (1993)]. {copyright} {ital 1997 American Institute of Physics.}« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27159801','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27159801">What is the acceptable hemolysis index for the measurements of plasma potassium, LDH and AST?</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Rousseau, Nathalie; Pige, Raphaëlle; Cohen, Richard; Pecquet, Matthieu 2016-06-01 Hemolysis is a cause of variability in test results for plasma potassium, LDH and AST and is a non-negligible part of measurement uncertainty. However, allowable levels of hemolysis provided by reagent suppliers take neither analytical variability (trueness and precision) nor the measurand into account. Using a calibration range of hemolysis, we measured the plasma concentrations of potassium, LDH and AST, and hemolysis indices with a Cobas C501 analyzer (Roche Diagnostics(®), Meylan, France). Based on the allowable total error (according to Ricós et al.) and the expanded measurement uncertainty equation we calculated the maximum allowable bias for two concentrations of each measurand. Finally, we determined the allowable hemolysis indices for all three measurands. We observed a linear relationship between the observed increases of concentration and hemolysis indices. The LDH measurement was the most sensitive to hemolysis, followed by AST and potassium measurements. The determination of the allowable hemolysis index depends on the targeted measurand, its concentration and the chosen level of requirement of allowable total error. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009PhDT.........1V','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009PhDT.........1V">Modeling magnetic field amplification in nonlinear diffusive shock acceleration</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Vladimirov, Andrey 2009-02-01 This research was motivated by the recent observations indicating very strong magnetic fields at some supernova remnant shocks, which suggests in-situ generation of magnetic turbulence. The dissertation presents a numerical model of collisionless shocks with strong amplification of stochastic magnetic fields, self-consistently coupled to efficient shock acceleration of charged particles. Based on a Monte Carlo simulation of particle transport and acceleration in nonlinear shocks, the model describes magnetic field amplification using the state-of-the-art analytic models of instabilities in magnetized plasmas in the presence of non-thermal particle streaming. The results help one understand the complex nonlinear connections between the thermal plasma, the accelerated particles and the stochastic magnetic fields in strong collisionless shocks. Also, predictions regarding the efficiency of particle acceleration and magnetic field amplification, the impact of magnetic field amplification on the maximum energy of accelerated particles, and the compression and heating of the thermal plasma by the shocks are presented. Particle distribution functions and turbulence spectra derived with this model can be used to calculate the emission of observable nonthermal radiation. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16968052','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16968052">Occurrence of the free and Peptide forms of pyroglutamic acid in plasma from the portal blood of rats that had ingested a wheat gluten hydrolysate containing pyroglutamyl peptides.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Higaki-Sato, Noriko; Sato, Kenji; Inoue, Naomi; Nawa, Yuko; Kido, Yasuhiro; Nakabou, Yukihiro; Hashimoto, Kaori; Nakamura, Yasushi; Ohtsuki, Kozo 2006-09-20 In order to determine pyroglutamic acid levels in plasma, we developed a method based on precolumn derivatization of the carboxyl group of pyroglutamic acid with 2-nitrophenylhydrazine. Eight-week-old male SD strain rats were administered 200 mg of an acidic peptide fraction obtained from a commercial wheat gluten hydrolysate containing 0.63 mmol/g pyroglutamyl peptide. After administration, significant amounts of free pyroglutamic acid were observed in the ethanol-soluble fraction of the plasma from the portal vein. In addition, pyroglutamate aminopeptidase digestion of the ethanol-soluble fraction liberated significant amounts of pyroglutamic acid, which indicated the presence of the pyroglutamyl peptide. The presence of the pyroglutamyl peptide in the plasma was further confirmed by size exclusion chromatography. The levels of free and peptide forms of pyroglutamic acid increased significantly and reached a maximum (approximately 40 nmol/mL) at 15 and 30 min after administration, respectively. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4926482','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4926482">Bioavailability of an R-α-Lipoic Acid/γ-Cyclodextrin Complex in Healthy Volunteers</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Ikuta, Naoko; Okamoto, Hinako; Furune, Takahiro; Uekaji, Yukiko; Terao, Keiji; Uchida, Ryota; Iwamoto, Kosuke; Miyajima, Atsushi; Hirota, Takashi; Sakamoto, Norihiro 2016-01-01 R-α-lipoic acid (R-LA) is a cofactor of mitochondrial enzymes and a very strong antioxidant. R-LA is available as a functional food ingredient but is unstable against heat or acid. Stabilized R-LA was prepared through complexation with γ-cyclodextrin (CD), yielding R-LA/CD. R-LA/CD was orally administered to six healthy volunteers and showed higher plasma levels with an area under the plasma concentration-time curve that was 2.5 times higher than that after oral administration of non-complexed R-LA, although the time to reach the maximum plasma concentration and half-life did not differ. Furthermore, the plasma glucose level after a single oral administration of R-LA/CD or R-LA was not affected and no side effects were observed. These results indicate that R-LA/CD could be easily absorbed in the intestine. In conclusion, γ-CD complexation is a promising technology for delivering functional but unstable ingredients like R-LA. PMID:27314343 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018AIPA....8e5321D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018AIPA....8e5321D">Model analysis and electrical characterization of atmospheric pressure cold plasma jet in pin electrode configuration</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Deepak, G. Divya; Joshi, N. K.; Prakash, Ram 2018-05-01 In this study, both model analysis and electrical characterization of a dielectric barrier discharge based argon plasma jet have been carried at atmospheric pressure in a pin electrode configuration. The plasma and fluid dynamics modules of COMSOL multi-physics code have been used for the modeling of the plasma jet. The plasma parameters, such as, electron density, electron temperature and electrical potential have been analyzed with respect to the electrical parameters, i.e., supply voltage and supply frequency with and without the flow of gas. In all the experiments, gas flow rate has been kept constant at 1 liter per minute. This electrode configuration is subjected to a range of supply frequencies (10-25 kHz) and supply voltages (3.5-6.5 kV). The power consumed by the device has been estimated at different applied combinations (supply voltage & frequency) for optimum power consumption at maximum jet length. The maximum power consumed by the device in this configuration for maximum jet length of ˜26 mm is just ˜1 W. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19730009998','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19730009998">Performance of an ion-cyclotron-wave plasma apparatus operated in the radiofrequency sustained mode</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Swett, C. C.; Woollett, R. R. 1973-01-01 An experimental study has been made of an ion-cyclotron-wave apparatus operated in the RF-sustained mode, that is, a mode in which the Stix RF coil both propagates the waves and maintains the plasma. Problems associated with this method of operation are presented. Some factors that are important to the coupling of RF power are noted. In general, the wave propagation and wave damping data agree with theory. Some irregularities in wave fields are observed. Maximum ion temperature is 870 eV at a density of five times 10 to the 12th power cu cm and RF power of 90 kW. Coupling efficiency is 70 percent. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19720018990','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19720018990">Operating features of an ion-cyclotron-wave plasma apparatus running in the RF-sustained mode</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Swett, C. C. 1972-01-01 An experimental study has been made of an ion-cyclotron-wave apparatus operated in the RF-sustained mode. This is a mode in which the Stix RF coil both propagates the waves and maintains the plasma. Problems associated with this method of operation are presented. Some factors that are important to the coupling of RF power are noted. In general, the wave-propagation and wave-damping data agree with theory. Some irregularities in wave fields are observed. Maximum ion temperature is 870 eV at a density of 5 times 10 to the 12th power per cubic centimeter and RF power of 90 kW. Coupling efficiency is 70 percent. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15816372','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15816372">A six month mitotane course induced sustained correction of hypercortisolism in a young woman with PPNAD and Carney complex.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Cignarelli, M; Picca, G; Campo, M; Margaglione, M; Marino, A; Logoluso, F; Giorgino, F 2005-01-01 A low-dose mitotane (MT) regimen was evaluated as a pharmacological approach for correcting the severe hypercortisolism in a young woman affected by Carney complex (CNC) and primary pigmented nodular adrenocortical disease (PPNAD). In the first 12 week period, the MT daily dose was progressively increased from 0.5 to 4.0 g/day. This dosage was maintained for an additional 16 weeks (cumulative dose 602 g, plasma MT maximum level 12 microg/ml), and then stopped because of sustained signs of hypoadrenalism requiring prednisone replacement. Complete regression of seborrhea, acne, and plethora was observed after 8 weeks of treatment (cumulative dose 95 g). Regular menses returned after 13 weeks (cumulative dose 197 g, plasma MT 8 microg/ml). Profound decrease of both serum cortisol (from 615 to 220 nmol/l) and urinary free cortisol (UFC) values (from 1498 to 477 nmol/day) was noted after 16 weeks of treatment (cumulative dose 314 g, plasma MT 8 microg/ml). MT treatment was associated with mild gastric discomfort and reversible increase of cholesterol plasma levels. Low serum cortisol and UFC were still observed 41 weeks after MT was discontinued (plasma MT 0.2 microg/ml). Our report demonstrates that low dose MT treatment may be a safe and effective modality for a sustained correction of hypercortisolism by PPNAD in subjects with CNC waiting for surgery. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22599179-observation-quasi-coherent-edge-fluctuations-ohmic-plasmas-national-spherical-torus-experiment','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22599179-observation-quasi-coherent-edge-fluctuations-ohmic-plasmas-national-spherical-torus-experiment">Observation of quasi-coherent edge fluctuations in Ohmic plasmas on National Spherical Torus Experiment</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Banerjee, Santanu; Diallo, A.; Zweben, S. J. A quasi-coherent edge density mode with frequency f{sub mode} ∼ 40 kHz is observed in Ohmic plasmas in National Spherical Torus Experiment using the gas puff imaging diagnostic. This mode is located predominantly just inside the separatrix, with a maximum fluctuation amplitude significantly higher than that of the broadband turbulence in the same frequency range. The quasi-coherent mode has a poloidal wavelength λ{sub pol} ∼ 16 cm and a poloidal phase velocity of V{sub pol} ∼ 4.9 ± 0.3 km s{sup −1} in the electron diamagnetic direction, which are similar to the characteristics expected from a linear drift-wave-like mode in the edge. This is the first observation of amore » quasi-coherent edge mode in an Ohmic diverted tokamak, and so may be useful for validating tokamak edge turbulence codes.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1400836','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1400836">Enoxacin decreases the clearance of theophylline in man.</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Wijnands, W J; Vree, T B; Van Herwaarden, C L 1985-01-01 In patients treated concurrently with theophylline and enoxacin, a new broad-spectrum antibacterial agent of the quinolone class, unexpectedly high plasma theophylline concentrations were measured. In part I of this study, daily plasma theophylline concentrations were measured in 14 patients. The mean +/- s.d. theophylline concentrations increased from 8.5 +/- 2.8 micrograms ml-1 prior to enoxacin to a maximum of 21.7 +/- 7.8 micrograms ml-1 during coadministration. In part II, six of these patients received aminophylline intravenously at a constant infusion rate and under controlled conditions. Plasma theophylline concentrations rose from 8.4 +/- 2.4 micrograms ml-1 prior to enoxacin treatment to 15.0 +/- 5.1 micrograms ml-1 at day 3 of coadministration (P less than 0.005). Plasma protein-binding and renal clearance of theophylline remained unchanged, whereas total body clearance of theophylline significantly decreased (P less than 0.005). From these observations it is concluded that the rise of plasma theophylline concentrations is caused by a reduced metabolic clearance of theophylline. If concomitant use of both drugs is necessary, monitoring of plasma theophylline concentration and adjustment of the theophylline dose is recommended. PMID:3867394 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25184109','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25184109">Irradiation of silver and agar/silver nanoparticles with argon, oxygen glow discharge plasma, and mercury lamp.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Ahmad, Mahmoud M; Abdel-Wahab, Essam A; El-Maaref, A A; Rawway, Mohammed; Shaaban, Essam R 2014-01-01 The irradiation effect of argon, oxygen glow discharge plasma, and mercury lamp on silver and agar/silver nanoparticle samples is studied. The irradiation time dependence of the synthesized silver and agar/silver nanoparticle absorption spectra and their antibacterial effect are studied and compared. In the agar/silver nanoparticle sample, as the irradiation time of argon glow discharge plasma or mercury lamp increases, the peak intensity and the full width at half maximum, FWHM, of the surface plasmon resonance absorption band is increased, however a decrease of the peak intensity with oxygen glow plasma has been observed. In the silver nanoparticle sample, as the irradiation time of argon, oxygen glow discharge plasma or mercury lamp increases, the peak intensity of the surface plasmon resonance absorption band is increased, however, there is no significant change in the FWHM of the surface plasmon resonance absorption band. The SEM results for both samples showed nanoparticle formation with mean size about 50 nm and 40 nm respectively. Throughout the irradiation time with the argon, oxygen glow discharge plasma or mercury lamp, the antibacterial activity of several kinds of Gram-positive and Gram-negative bacteria has been examined. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li class="active">9</li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_10" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li class="active">10</li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="181"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFMSM11G..07B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFMSM11G..07B">Plasma Pancakes and Deep Cavities Generated by High Power Radio Waves from the Arecibo Observatory</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Bernhardt, P. A.; Briczinski, S. J., Jr.; Zawdie, K.; Huba, J.; Siefring, C. L.; Sulzer, M. P.; Nossa, E.; Aponte, N.; Perillat, P.; Jackson-Booth, N. 2017-12-01 Breakdown of the neutral atmosphere at ionospheric altitudes can be achieved with high power HF waves that reflect on the bottomside of the ionosphere. For overdense heating (i.e., wave frequency < maximum plasma frequency in the F-layer), the largest electric fields in the plasma are found just below the reflection altitude. There, electromagnetic waves are converted into electron plasma (Langmir) waves and ion acoustic waves. These waves are measured by scattering of the 430 MHz radar at Arecibo to from an enhanced plasma line. The photo-electron excitation of Langmuir waves yields a weaker plasma-line profile that shows the complete electron profile with the radar. Once HF enhanced Langmuir waves are formed, they can accelerate the photo-electron population to sufficient energies for neutral breakdown and enhanced ionization inside the HF Radio Beam. Plasma pancakes are produced because the breakdown process continues to build up plasma on bottom of the breakdown clouds and recombination occurs on the older breakdown plasma at the top of these clouds. Thus, the plasma pancake falls with altitude from the initial HF wave reflection altitude near 250 km to about 160 km where ion-electron recombination prevents the plasma cloud from being sustained by the high power HF. Experiments in March 2017 have produced plasma pancakes with about 100 Mega-Watts effective radiated power 5.1 MHz with the Arecibo HF Facility. Observations using the 430 MHz radar show falling plasma pancakes that disappear at low altitudes and reform at the F-layer critical reflection altitude. Sometimes the periodic and regular falling motion of the plasma pancakes is influenced by Acoustic Gravity Waves (AGW) propagating through the modified HF region. A rising AGW can cause the plasma pancake to reside at nearly constant altitude for 10 to 20 minutes. Dense cavities are also produced by high power radio waves interacting with the F-Layer. These structures are observed with the Arecibo 430 MHz radar as intense bight-outs in the plasma profile. Multiple cavities are seen simultaneously. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19910068898&hterms=foreshock&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Dforeshock','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19910068898&hterms=foreshock&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Dforeshock">Variations in plasma wave intensity with distance along the electron foreshock boundary at Venus</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Crawford, G. K.; Strangeway, R. J.; Russell, C. T. 1991-01-01 Plasma waves are observed in the solar wind upstream of the Venus bow shock by the Pioneer Venus Orbiter. These wave signatures occur during periods when the interplanetary magnetic field through the spacecraft position intersects the bow shock, thereby placing the spacecraft in the foreshock region. Wave intensity is analyzed as a function of distance along the electron foreshock boundary. It is found that the peak wave intensity may increase along the foreshock boundary from the tangent point to a maximum value at several Venus radii, then decrease in intensity with subsequent increase in distance. These observations could be associated with the instability process: the instability of the distribution function increasing with distance from the tangent point to saturation at the peak. Thermalization of the beam for distances beyond this point could reduce the distribution function instability resulting in weaker wave signatures. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22228115-high-contrast-ion-acceleration-intensities-exceeding-sup-wcm-sup','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22228115-high-contrast-ion-acceleration-intensities-exceeding-sup-wcm-sup">High contrast ion acceleration at intensities exceeding 10{sup 21} Wcm{sup −2}</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Dollar, F.; Zulick, C.; Matsuoka, T. 2013-05-15 Ion acceleration from short pulse laser interactions at intensities of 2×10{sup 21}Wcm{sup −2} was studied experimentally under a wide variety of parameters, including laser contrast, incidence angle, and target thickness. Trends in maximum proton energy were observed, as well as evidence of improvement in the acceleration gradients by using dual plasma mirrors over traditional pulse cleaning techniques. Extremely high efficiency acceleration gradients were produced, accelerating both the contaminant layer and high charge state ions from the bulk of the target. Two dimensional particle-in-cell simulations enabled the study of the influence of scale length on submicron targets, where hydrodynamic expansion affectsmore » the rear surface as well as the front. Experimental evidence of larger electric fields for sharp density plasmas is observed in simulation results as well for such targets, where target ions are accelerated without the need for contaminant removal.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19900033253&hterms=Sacramento+CA&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3DSacramento%252C%2BCA','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19900033253&hterms=Sacramento+CA&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3DSacramento%252C%2BCA">Momentum balance in four solar flares</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Canfield, Richard C.; Metcalf, Thomas R.; Zarro, Dominic M.; Lemen, James R. 1990-01-01 Solar Maximum Mission soft X-ray spectra and National Solar Observatory (Sacramento Peak) H-alpha spectra were combined in a study of high-speed flows during the impulsive phase of four solar flares. In all events, a blue asymmetry (indicative of upflows) was observed in the coronal Ca XIX line during the soft X-ray rise phase. In all events a red asymmetry (indicative of downflows) was observed simultaneously in chromospheric H-alpha. These oppositely directed flows were concurrent with impulsive hard X-ray emission. Combining the velocity data with estimates of the density based on emission measurements and volume estimates, it is shown that for the impulsive phase as a whole the total momentum of upflowing soft X-ray plasma equaled that of the downflowing H-alpha plasma, to within an order of magnitude, in all four events. Only the chromospheric evaporation model predicts equal total momentum in the upflowing soft X-ray-emitting and downflowing H-alphba-emitting materials. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26849997','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26849997">Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Strajhar, P; Schmid, Y; Liakoni, E; Dolder, P C; Rentsch, K M; Kratschmar, D V; Odermatt, A; Liechti, M E 2016-03-01 Lysergic acid diethylamide (LSD) is a serotonin 5-hydroxytryptamine-2A (5-HT2A ) receptor agonist that is used recreationally worldwide. Interest in LSD research in humans waned after the 1970s, although the use of LSD in psychiatric research and practice has recently gained increasing attention. LSD produces pronounced acute psychedelic effects, although its influence on plasma steroid levels over time has not yet been characterised in humans. The effects of LSD (200 μg) or placebo on plasma steroid levels were investigated in 16 healthy subjects using a randomised, double-blind, placebo-controlled, cross-over study design. Plasma concentration-time profiles were determined for 15 steroids using liquid-chromatography tandem mass-spectrometry. LSD increased plasma concentrations of the glucocorticoids cortisol, cortisone, corticosterone and 11-dehydrocorticosterone compared to placebo. The mean maximum concentration of LSD was reached at 1.7 h. Mean peak psychedelic effects were reached at 2.4 h, with significant alterations in mental state from 0.5 h to > 10 h. Mean maximal concentrations of cortisol and corticosterone were reached at 2.5 h and 1.9 h, and significant elevations were observed 1.5-6 h and 1-3 h after drug administration, respectively. LSD also significantly increased plasma concentrations of the androgen dehydroepiandrosterone but not other androgens, progestogens or mineralocorticoids compared to placebo. A close relationship was found between plasma LSD concentrations and changes in plasma cortisol and corticosterone and the psychotropic response to LSD, and no clockwise hysteresis was observed. In conclusion, LSD produces significant acute effects on circulating steroids, especially glucocorticoids. LSD-induced changes in circulating glucocorticoids were associated with plasma LSD concentrations over time and showed no acute pharmacological tolerance. © 2016 British Society for Neuroendocrinology. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19740030338&hterms=performance+banks&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Dperformance%2Bbanks','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19740030338&hterms=performance+banks&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Dperformance%2Bbanks">20 kA PFN capacitor bank with solid-state switching. [pulse forming network for plasma studies</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Posta, S. J.; Michels, C. J. 1973-01-01 A compact high-current pulse-forming network capacitor bank using paralleled silicon controlled rectifiers as switches is described. The maximum charging voltage of the bank is 1kV and maximum load current is 20 kA. The necessary switch equalization criteria and performance with dummy load and an arc plasma generator are described. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=84793','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=84793">Comparison of Cytomegalovirus Loads in Plasma and Leukocytes of Patients with Cytomegalovirus Retinitis</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Jabs, Douglas A.; Forman, Michael; Enger, Cheryl; Jackson, J. Brooks 1999-01-01 Cytomegalovirus (CMV) DNA loads in paired leukocyte and plasma samples from 199 patient visits by 66 patients with CMV retinitis were determined. Leukocyte CMV load determinations had a greater range of values (mean, 24,587 copies/106 leukocytes; maximum, 539,000) than did plasma CMV load determinations (mean, 10,302 copies/ml; maximum, 386,000), and leukocyte viral loads were detectable in a greater proportion of patients at the time of diagnosis of CMV retinitis prior to initiation of anti-CMV therapy (82%) than were plasma viral loads (64%) (P = 0.0078). Agreement with CMV blood cultures was slightly better for plasma (κ = 0.68) than for leukocytes (κ = 0.53), due to a greater proportion of patients with detectable viral loads in leukocytes having negative blood cultures. PMID:10203500 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1401821','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1401821">Effect of chronic diuretic treatment on the plasma renin-angiotensin-aldosterone system in essential hypertension.</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Lijnen, P; Fagard, R; Staessen, J; Amery, A 1981-01-01 1 Chronic treatment with a constant dose of hydrochlorothiazide or tienilic acid increases plasma renin activity (PRA) acutely to reach a maximum within the first week. 2 During chronic diuretic therapy from 1 month to 1 year, PRA remained elevated at a rather constant level, though this was somewhat lower than the maximum level reached after 1 week. 3 A significant (P less than 0.01) correlation (r = 0.74) between changes in plasma angiotensin II and renin activity provoked by chronic treatment for 3 months with hydrochlorothiazide and tienilic acid was found. 4 The increase in plasma aldosterone during chronic treatment with hydrochlorothiazide and tienilic acid (1000 mg) is related (r = 0.68; P less than 0.01) to the rise in plasma angiotensin II. PMID:7028060 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFMSH53B...2C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFMSH53B...2C">Interplanetary shocks, Plasma waves and turbulence, Kinetic waves and instabilities, STEREO spacecraft</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Cohen, Z.; Breneman, A. W.; Cattell, C. A.; Davis, L.; Grul, P.; Kersten, K.; Wilson, L. B., III 2017-12-01 Determining the role of plasma waves in providing energy dissipation at shock waves is of long-standing interest. Interplanetary (IP) shocks serve as a large database of low Mach number shocks. We examine electric field waveforms captured by the Time Domain Sampler (TDS) on the STEREO spacecraft during the ramps of IP shocks, with emphasis on captures lasting 2.1 seconds. Previous work has used captures of shorter duration (66 and 131 ms on STEREO, and 17 ms on WIND), which allowed for observation of waves with maximum (minimum) frequencies of 125 kHz (15 Hz), 62.5 kHz (8 Hz), and 60 kHz (59 Hz), respectively. The maximum frequencies are comparable to 2-8 times the plasma frequency in the solar wind, enabling observation of Langmuir waves, ion acoustic, and some whistler-mode waves. The 2 second captures resolve lower frequencies ( few Hz), which allows us to analyze packet structure of the whistler-mode waves and some ion acoustic waves. The longer capture time also improves the resolvability of simultaneous wave modes and of waves with frequencies on the order of 10s of Hz. Langmuir waves, however, cannot be identified at this sampling rate, since the plasma frequency is usually higher than 3.9 kHz. IP shocks are identified from multiple databases (Helsinki heliospheric shock database at http://ipshocks.fi, and the STEREO level 3 shock database at ftp://stereoftp.nascom.nasa.gov/pub/ins_data/impact/level3/). Our analysis focuses on TDS captures in shock ramp regions, with ramp durations determined from magnetic field data taken at 8 Hz. Software is used to identify multiple wave modes in any given capture and classify waves as Langmuir, ion acoustic, whistler, lower hybrid, electron cyclotron drift instability, or electrostatic solitary waves. Relevant frequencies are determined from density and magnetic field data collected in situ. Preliminary results suggest that large amplitude (∼ 5 mV/m) ion acoustic waves are most prevalent in the ramp, in agreement with Wilson, et al. Other modes are also observed. Statistical results will be presented and compared with previous studies and theoretical predictions. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/20797913-about-extreme-achievable-current-plasma-focus-installation-mather-type','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/20797913-about-extreme-achievable-current-plasma-focus-installation-mather-type">About an Extreme Achievable Current in Plasma Focus Installation of Mather Type</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Nikulin, V. Ya.; Polukhin, S. N.; Vikhrev, V. V. A computer simulation and analytical analysis of the discharge process in Plasma Focus has shown that there is an upper limit to the current which can be achieved in Plasma Focus installation of Mather type by only increasing the capacity of the condenser bank. The maximum current achieved for various plasma focus installations of 1 MJ level is discussed. For example, for the PF-1000 (IFPiLM) and 1 MJ Frascati PF, the maximum current is near 2 MA. Thus, the commonly used method of increasing the energy of the PF installation by increasing of the capacity has no merit. Alternative optionsmore » in order to increase the current are discussed.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22800813','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22800813">Direct measurements of sample heating by a laser-induced air plasma in pre-ablation spark dual-pulse laser-induced breakdown spectroscopy (LIBS).</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Register, Janna; Scaffidi, Jonathan; Angel, S Michael 2012-08-01 Direct measurements of temperature changes were made using small thermocouples (TC), placed near a laser-induced air plasma. Temperature changes up to ~500 °C were observed. From the measured temperature changes, estimates were made of the amount of heat absorbed per unit area. This allowed calculations to be made of the surface temperature, as a function of time, of a sample heated by the air plasma that is generated during orthogonal pre-ablation spark dual-pulse (DP) LIBS measurements. In separate experiments, single-pulse (SP) LIBS emission and sample ablation rate measurements were performed on nickel at sample temperatures ranging from room temperature to the maximum surface temperature that was calculated using the TC measurement results (500 °C). A small, but real sample temperature-dependent increase in both SP LIBS emission and the rate of sample ablation was found for nickel samples heated up to 500 °C. Comparison of DP LIBS emission enhancement values for bulk nickel samples at room temperature versus the enhanced SP LIBS emission and sample ablation rates observed as a function of increasing sample temperature suggests that sample heating by the laser-induced air plasma plays only a minor role in DP LIBS emission enhancement. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=542546','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=542546">Studies on the Mechanism of Action of Dinitramine</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Travis, Robert L.; Woods, William G. 1977-01-01 The effect of dinitramine, a selective herbicide, on the plasma membrane of the soybean (Glycine max L.) root was studied. Used as marker systems to observe the herbicide effect were two plasma-membrane-specific enzymes, pH 6.5 ATPase and glucan synthetase. The activity of pH 6.5 ATPase decreased significantly in membrane vesicles prepared from roots harvested 15 minutes after treatment with dinitramine. Maximum inhibition occurred in roots harvested 2 hours after treatment. Glucan synthetase activity decreased similarly within 2 hours of treatment. Membrane permeability to 86Rb was rapidly increased by dinitramine. The activity of pH 6.5 ATPase returned to the control level within 8 hours of treatment with dinitramine. These results show dinitramine's initial site of action to be the plasma membrane, producing an over-all reduction in membrane function through inactivation of membrane-associated proteins. PMID:16660043 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JaJAP..57aAB01O','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JaJAP..57aAB01O">Atmospheric-pressure plasma jet system for silicon etching without fluorocarbon gas feed</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Ohtsu, Yasunori; Nagamatsu, Kenta 2018-01-01 We developed an atmospheric-pressure plasma jet (APPJ) system with a tungsten rod electrode coated with C2F4 particles of approximately 0.3 µm diameter for the surface treatment of a silicon wafer. The APPJ was generated by dielectric barrier discharge with a driving frequency of 22 kHz using a He gas flow. The characteristics of the APPJ were examined under various experimental conditions. The plasma jet length increased proportionally to the electric field. It was found that the treatment area of the silicon wafer was approximately 1 mm in diameter. By atomic force microscopy analysis, minute irregularities with a maximum length of about 600 nm and part of a ring-shaped trench were observed. A Si etching rate of approximately 400 nm/min was attained at a low power of 6 W and a He flow rate of 1 L/min without introducing molecular gas including F atoms. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1999JaJAP..38.4512U','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1999JaJAP..38.4512U">Relationship between Intensity of Fullerene-Mass Spectrum and Carbon Vibrational Temperature in Microwave-Helium Plasmas</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Ueda, Kengo; Kuwahara, Kiyoshi; Fujiyama, Hiroshi 1999-07-01 Soot containing fullerenes, such as C60 and C70, was synthesized with He plasmas generated in a quartz tube by microwave-glow discharge. A reticulated vitreous carbon (RVC) heated by the microwave He plasmas with an electric field of TE10 mode was used as the carbon source. Swan bands of C2 molecules were observed during the synthesis by optical emission spectroscopy (OES) in order to investigate the effect of the vibrational temperature of C2 molecules on the formation of the fullerenes. The soot deposited on the quartz tube was analyzed by laser desorption time-of-flight mass-spectroscopy (LD-TOF-MS). The intensities of the mass spectra of fullerenes were confirmed to be maximum for the conditions as follows: the absorbed microwave power Pab=200 W and the He gas pressure P=100 Torr, while the C2 vibrational temperature was approximately 7000 K. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015JaJAP..54aAE04N','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015JaJAP..54aAE04N">Experimental study of the visible-light photocatalytic activity of oxygen-deficient TiO2 prepared with Ar/H2 plasma surface treatment</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Nakano, Takuma; Yazawa, Shota; Araki, Shota; Kogoshi, Sumio; Katayama, Noboru; Kudo, Yusuke; Nakanishi, Tetsuya 2015-01-01 Oxygen-deficient TiO2 (TiO2-x) has been proposed as a visible-light-responsive photocatalyst. TiO2-x thin films were prepared by Ar/H2 plasma surface treatment, applying varying levels of microwave input power and processing times. The highest visible light photocatalytic activity was observed when using an input power of 200 W, a plasma processing time of 10 min, and a 1:1 \\text{Ar}:\\text{H}2 ratio, conditions that generate an electron temperature of 5.7(±1.0) eV and an electron density of 8.5 × 1010 cm-3. The maximum formaldehyde (HCHO) removal rate of the TiO2-x film was 2.6 times higher than that obtained from a TiO2-xNx film under the same test conditions. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19780061649&hterms=1057&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3D%2526%25231057','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19780061649&hterms=1057&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3D%2526%25231057">Magnetic loops, downflows, and convection in the solar corona</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Foukal, P. 1978-01-01 Optical and extreme-ultraviolet observations of solar loop structures show that flows of cool plasma from condensations near the loop apex are a common property of loops associated with radiations whose maximum temperature is greater than approximately 7000 K and less than approximately 3,000,000 K. It is suggested that the mass balance of these structures indicates reconnection by means of plasma motion across field lines under rather general circumstances (not only after flares). It is shown that the cool material has lower gas pressure than the surrounding coronal medium. The density structure of the bright extreme ultraviolet loops suggests that downflows of cool gas result from isobaric condensation of plasma that is either out of thermal equilibrium with the local energy deposition rate into the corona, or is thermally unstable. The evidence is thought to indicate that magnetic fields act to induce a pattern of forced convection. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFMSA12A..06Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFMSA12A..06Y">Vertical Rise Velocity of Equatorial Plasma Bubbles Estimated from Equatorial Atmosphere Radar Observations and High-Resolution Bubble Model Simulations</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Yokoyama, T.; Ajith, K. K.; Yamamoto, M.; Niranjan, K. 2017-12-01 Equatorial plasma bubble (EPB) is a well-known phenomenon in the equatorial ionospheric F region. As it causes severe scintillation in the amplitude and phase of radio signals, it is important to understand and forecast the occurrence of EPBs from a space weather point of view. The development of EPBs is presently believed as an evolution of the generalized Rayleigh-Taylor instability. We have already developed a 3D high-resolution bubble (HIRB) model with a grid spacing of as small as 1 km and presented nonlinear growth of EPBs which shows very turbulent internal structures such as bifurcation and pinching. As EPBs have field-aligned structures, the latitude range that is affected by EPBs depends on the apex altitude of EPBs over the dip equator. However, it was not easy to observe the apex altitude and vertical rise velocity of EPBs. Equatorial Atmosphere Radar (EAR) in Indonesia is capable of steering radar beams quickly so that the growth phase of EPBs can be captured clearly. The vertical rise velocities of the EPBs observed around the midnight hours are significantly smaller compared to those observed in postsunset hours. Further, the vertical growth of the EPBs around midnight hours ceases at relatively lower altitudes, whereas the majority of EPBs at postsunset hours found to have grown beyond the maximum detectable altitude of the EAR. The HIRB model with varying background conditions are employed to investigate the possible factors that control the vertical rise velocity and maximum attainable altitudes of EPBs. The estimated rise velocities from EAR observations at both postsunset and midnight hours are, in general, consistent with the nonlinear evolution of EPBs from the HIRB model. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/20040171393','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20040171393">The Fraction of Interplanetary Coronal Mass Ejections That Are Magnetic Clouds: Evidence for a Solar Cycle Variation</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Richardson, I. G.; Cane, H. V. 2004-01-01 "Magnetic clouds" (MCs) are a subset of interplanetary coronal mass ejections (ICMEs) characterized by enhanced magnetic fields with an organized rotation in direction, and low plasma beta. Though intensely studied, MCs only constitute a fraction of all the ICMEs that are detected in the solar wind. A comprehensive survey of ICMEs in the near- Earth solar wind during the ascending, maximum and early declining phases of solar cycle 23 in 1996 - 2003 shows that the MC fraction varies with the phase of the solar cycle, from approximately 100% (though with low statistics) at solar minimum to approximately 15% at solar maximum. A similar trend is evident in near-Earth observations during solar cycles 20 - 21, while Helios 1/2 spacecraft observations at 0.3 - 1.0 AU show a weaker trend and larger MC fraction. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22220395-application-maximum-likelihood-methods-laser-thomson-scattering-measurements-low-density-plasmas','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22220395-application-maximum-likelihood-methods-laser-thomson-scattering-measurements-low-density-plasmas">Application of maximum likelihood methods to laser Thomson scattering measurements of low density plasmas</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Washeleski, Robert L.; Meyer, Edmond J. IV; King, Lyon B. 2013-10-15 Laser Thomson scattering (LTS) is an established plasma diagnostic technique that has seen recent application to low density plasmas. It is difficult to perform LTS measurements when the scattered signal is weak as a result of low electron number density, poor optical access to the plasma, or both. Photon counting methods are often implemented in order to perform measurements in these low signal conditions. However, photon counting measurements performed with photo-multiplier tubes are time consuming and multi-photon arrivals are incorrectly recorded. In order to overcome these shortcomings a new data analysis method based on maximum likelihood estimation was developed. Themore » key feature of this new data processing method is the inclusion of non-arrival events in determining the scattered Thomson signal. Maximum likelihood estimation and its application to Thomson scattering at low signal levels is presented and application of the new processing method to LTS measurements performed in the plume of a 2-kW Hall-effect thruster is discussed.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24182157','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24182157">Application of maximum likelihood methods to laser Thomson scattering measurements of low density plasmas.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Washeleski, Robert L; Meyer, Edmond J; King, Lyon B 2013-10-01 Laser Thomson scattering (LTS) is an established plasma diagnostic technique that has seen recent application to low density plasmas. It is difficult to perform LTS measurements when the scattered signal is weak as a result of low electron number density, poor optical access to the plasma, or both. Photon counting methods are often implemented in order to perform measurements in these low signal conditions. However, photon counting measurements performed with photo-multiplier tubes are time consuming and multi-photon arrivals are incorrectly recorded. In order to overcome these shortcomings a new data analysis method based on maximum likelihood estimation was developed. The key feature of this new data processing method is the inclusion of non-arrival events in determining the scattered Thomson signal. Maximum likelihood estimation and its application to Thomson scattering at low signal levels is presented and application of the new processing method to LTS measurements performed in the plume of a 2-kW Hall-effect thruster is discussed. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li class="active">10</li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_11" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li class="active">11</li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="201"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014PhDT........99J','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014PhDT........99J">Development of high energy pulsed plasma simulator for plasma-lithium trench experiment</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Jung, Soonwook To simulate detrimental events in a tokamak and provide a test-stand for a liquid lithium infused trench (LiMIT) device, a pulsed plasma source utilizing a theta pinch in conjunction with a coaxial plasma accelerator has been developed. An overall objective of the project is to develop a compact device that can produce 100 MW/m2 to 1 GW/m2 of plasma heat flux (a typical heat flux level in a major fusion device) in ~ 100 mus (≤ 0.1 MJ/m2) for a liquid lithium plasma facing component research. The existing theta pinch device, DEVeX, was built and operated for study on lithium vapor shielding effect. However, a typical plasma energy of 3 - 4 kJ/m2 is too low to study an interaction of plasma and plasma facing components in fusion devices. No or little preionized plasma, ringing of magnetic field, collisions of high energy particles with background gas have been reported as the main issues. Therefore, DEVeX is reconfigured to mitigate these issues. The new device is mainly composed of a plasma gun for a preionization source, a theta pinch for heating, and guiding magnets for a better plasma transportation. Each component will be driven by capacitor banks and controlled by high voltage / current switches. Several diagnostics including triple Langmuir probe, calorimeter, optical emission measurement, Rogowski coil, flux loop, and fast ionization gauge are used to characterize the new device. A coaxial plasma gun is manufactured and installed in the previous theta pinch chamber. The plasma gun is equipped with 500 uF capacitor and a gas puff valve. The increase of the plasma velocity with the plasma gun capacitor voltage is consistent with the theoretical predictions and the velocity is located between the snowplow model and the weak - coupling limit. Plasma energies measured with the calorimeter ranges from 0.02 - 0.065 MJ/m2 and increases with the voltage at the capacitor bank. A cross-check between the plasma energy measured with the calorimeter and the triple probe / optics shows that the plasma energies are in agreement with each other. The effect of theta pinch on preionized plasma has been investigated when operated in conjunction with the coaxial plasma gun. The previous theta coil (1 turn, 40 nH) is connected with 72 muF capacitor bank to handle more energy. The theta coil is reconfigured as a two - turn coil (160 nH) to facilitate the operation of a crowbar. The two-turn coil achieves a maximum current of 300 kA (= 1.2 T) at 20 kV of the main capacitor bank voltage and the operation of the crowbar allows for a monotonically decreasing current. With the 2-turn theta coil, a maximum plasma energy of ~ 0.08 MJ/m2 is achieved with 6 kV at the plasma gun and 20 kV at the theta pinch. Plasma velocities of 34 - 74 km/s are observed at the first few peaks of theta pinch current. A problem of plasma transport with short delay times is observed. Finally, the dissertation concludes with a few ways to further improve the device and increase the plasma heat flux. A change in the system design as well as a compact toroid generation are proposed and preliminary results are presented. The dissertation also suggests hardware upgrades which include an increase in the energy at the plasma gun / the theta pinch capacitor banks. At the same time, additional diagnostics will allow to further investigate the effect of pinching on the plasma from the plasma gun as well as determine the overall effect of the guiding magnetic field. (Abstract shortened by UMI.). </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017PhPl...24e5601H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017PhPl...24e5601H">Electron holes in phase space: What they are and why they matter</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Hutchinson, I. H. 2017-05-01 This is a tutorial and selective review explaining the fundamental concepts and some currently open questions concerning the plasma phenomenon of the electron hole. The widespread occurrence of electron holes in numerical simulations, space-craft observations, and laboratory experiments is illustrated. The elementary underlying theory is developed of a one-dimensional electron hole as a localized potential maximum, self-consistently sustained by a deficit of trapped electron phase-space density. The spatial extent of a hole is typically a few Debye lengths; what determines the minimum and maximum possible lengths is explained, addressing the key aspects of the as yet unsettled dispute between the integral and differential approaches to hole structure. In multiple dimensions, holes tend to form less readily; they generally require a magnetic field and distribution-function anisotropy. The mechanisms by which they break up are explained, noting that this transverse instability is not fully understood. Examples are given of plasma circumstances where holes play an important role, and of recent progress on understanding their holistic kinematics and self-acceleration. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2008APS..DPPGP6118I','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2008APS..DPPGP6118I">Development of neutral beam injection system by use of washer gun plasma source</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Imanaka, Heizo; Kajiya, Hirotaka; Nemoto, Yuichi; Azuma, Akiyoshi; Asai, Tomoaki; Yamada, Takuma; Inomoto, Michiaki; Ono, Yasushi 2008-11-01 For the past ten years, we have been investigating high-beta Spherical Tokamaks (ST) formation using reconnection heating of their axial merging in the TS-4 experiment, University of Tokyo. The produced ST was observed to have the maximum beta of 50-60% right after the merging of two STs. A key issue after the formation is to maintain the produced high-beta ST over 100 Alfven times for its stability check. A new low-cost pulsed neutral beam injection (NBI) system has been arranged for its sustainment experiment. Its advantages are 1) low voltage (15kV for low-field side of ST) and high current (20A), 2) maintenance-free, 3) low-cost. The conventional filament plasma source was replaced by the washer gun to realize air-cooled and maintenance free NBI system. In its startup experiment, we already extracted the maximum beam current of 3.7A for then acceleration voltage of 10kV successfully. This result suggests that the increase in the acceleration voltage and several conditioning work will realize its designed beam parameters of 15kV, 20A. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2007PhPl...14e6316W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2007PhPl...14e6316W">Laser plasma instability experiments with KrF lasersa)</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Weaver, J. L.; Oh, J.; Afeyan, B.; Phillips, L.; Seely, J.; Feldman, U.; Brown, C.; Karasik, M.; Serlin, V.; Aglitskiy, Y.; Mostovych, A. N.; Holland, G.; Obenschain, S.; Chan, L.-Y.; Kehne, D.; Lehmberg, R. H.; Schmitt, A. J.; Colombant, D.; Velikovich, A. 2007-05-01 Deleterious effects of laser-plasma instability (LPI) may limit the maximum laser irradiation that can be used for inertial confinement fusion. The short wavelength (248nm), large bandwidth, and very uniform illumination available with krypton-fluoride (KrF) lasers should increase the maximum usable intensity by suppressing LPI. The concomitant increase in ablation pressure would allow implosion of low-aspect-ratio pellets to ignition with substantial gain (>20) at much reduced laser energy. The proposed KrF-laser-based Fusion Test Facility (FTF) would exploit this strategy to achieve significant fusion power (150MW) with a rep-rate system that has a per pulse laser energy well below 1 MJ. Measurements of LPI using the Nike KrF laser are presented at and above intensities needed for the FTF (I˜2×1015W/cm2). The results to date indicate that LPI is indeed suppressed. With overlapped beam intensity above the planar, single beam intensity threshold for the two-plasmon decay instability, no evidence of instability was observed via measurements of 3/2ωo and 1/2ωo harmonic emissions. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015APS..GECLW1142W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015APS..GECLW1142W">Mechanism of Growth Enhancement of Plants Induced by Active Species in Plasmas</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Watanabe, Satoshi; Ono, Reoto; Hayashi, Nobuya 2015-09-01 Plant growth enhances when seeds are irradiated by plasma. However the mechanism of the growth enhancement by plasma has not been clarified. In this study, growth enhancement of plants using various active species and variation of plant cells are investigated. RF plasma is generated under conditions where pressure is 60 Pa and input electrical power is 60 W. Irradiation period varies from 0 (control) to 75 min. Air plasma shows maximum growth of plants with irradiation period of 60 min on the other hand, oxygen plasma shows the maximum growth with irradiation period of 15 min. From change of gaseous species and pressure dependence, growth enhancing factor is expected to be active oxygen species produced in plasma. According to gene expression analysis of Arabidopsis, there are two speculated mechanism of plant growth enhancement. The first is acceleration of cell cycle by gene expressions of photosynthesis and glycolytic pathway, and the second is increase of cell size via plant hormone production. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=149862','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=149862">Negative specific heat of a magnetically self-confined plasma torus</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Kiessling, Michael K.-H.; Neukirch, Thomas 2003-01-01 It is shown that the thermodynamic maximum-entropy principle predicts negative specific heat for a stationary, magnetically self-confined current-carrying plasma torus. Implications for the magnetic self-confinement of fusion plasma are considered. PMID:12576553 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/6789865-experimental-study-plasma-properties-shadow-mushroom-limiter','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/6789865-experimental-study-plasma-properties-shadow-mushroom-limiter">Experimental study of plasma properties in the shadow of the T--10 mushroom limiter</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Alferov, A.A.; Vershkov, V.A.; Grashin, S.A. 1988-04-01 The plasma properties in the shadow of a mushroom-shaped limiter installed in a lower port of the tokamak have been studied. A study of the asymmetry of the plasma streams on the ion and electron sides of the limiter leads to the conclusion that there are two mechanisms for the occurrence of the asymmetry: the toroidal rotation of the plasma and a predominant escape of plasma to the wall through the outer part of the torus. The asymmetry observed in the plasma floating potentials near the limiter leads to the flow of a current close to the Spitzer value j/submore » S/ through the limiter. With increasing plasma density, the plasma density in the channels of the limiter increases, and the temperature of this plasma decreases, so the loss of charged particles to the limiter depends only weakly on the average density. This circumstance is related to the degradation of the plasma confinement with decreasing density. The total flux of charged particles to the limiter is comparable to the flux of these particles out of the plasma column. The plasma stream into the channels is approximately ambipolar, and the power levels drawn by the neutralization plate are on the order of 10j/sub S/T/sub e//e. The behavior of the neutral gas pressure in the volume near the limiter as a function of the plasma streams into the channels is nonlinear. The maximum pressure is 3x10/sup -2/ torr.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25850415','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25850415">Evaluation of the sensitivity of bacterial and yeast cells to cold atmospheric plasma jet treatments.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Sharkey, Michael A; Chebbi, Ahmed; McDonnell, Kevin A; Staunton, Claire; Dowling, Denis P 2015-06-07 The focus of this research was first to determine the influence of the atmospheric plasma drive frequency on the generation of atomic oxygen species and its correlation with the reduction of bacterial load after treatment in vitro. The treatments were carried out using a helium-plasma jet source called PlasmaStream™. The susceptibility of multiple microbial cell lines was investigated in order to compare the response of gram-positive and gram-negative bacteria, as well as a yeast cell line to the atmospheric plasma treatment. It was observed for the source evaluated that at a frequency of 160 kHz, increased levels of oxygen-laden active species (i.e., OH, NO) were generated. At this frequency, the maximum level of bacterial inactivation in vitro was also achieved. Ex vivo studies (using freshly excised porcine skin as a human analog) were also carried out to verify the antibacterial effect of the plasma jet treatment at this optimal operational frequency and to investigate the effect of treatment duration on the reduction of bacterial load. The plasma jet treatment was found to yield a 4 log reduction in bacterial load after 6 min of treatment, with no observable adverse effects on the treatment surface. The gram-negative bacterial cell lines were found to be far more susceptible to the atmospheric plasma treatments than the gram-positive bacteria. Flow cytometric analysis of plasma treated bacterial cells (Escherichia coli) was conducted in order to attain a fundamental understanding of the mode of action of the treatment on bacteria at a cellular level. This study showed that after treatment with the plasma jet, E. coli cells progressed through the following steps of cell death; the inactivation of transport systems, followed by depolarization of the cytoplasmic membrane, and finally permeabilization of the cell wall. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA160186','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA160186">Population Inversion and Gain Measurements for X-Ray Laser Development in Magnetically Confined Plasma Column in Fiscal Year 1984.</a> <a target="_blank" rel="noopener noreferrer" href="http://www.dtic.mil/">DTIC Science & Technology</a> 1985-03-20 lasing action, indicates an enhancement of the CVI 182 A line, and also population inversion for the Li-like CIV, OVI, FVII and NeVIII ions. Time...shot. Results with the carbon fibers were encouraging in that a maximum gain-length product of ki - 3.0 (k = 7.5 cm- 1 ) at 182 A was observed. The...particular, the OVI 173 A line, increased by a factor of 2 to 3 in comparison to our earlier data. V. 8 The CVI 182 A line was observed in time integrated </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26970526','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26970526">Extended-Release Once-Daily Formulation of Tofacitinib: Evaluation of Pharmacokinetics Compared With Immediate-Release Tofacitinib and Impact of Food.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Lamba, Manisha; Wang, Rong; Fletcher, Tracey; Alvey, Christine; Kushner, Joseph; Stock, Thomas C 2016-11-01 Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis. An extended-release (XR) formulation has been designed to provide a once-daily (QD) dosing option to patients to achieve comparable pharmacokinetic (PK) parameters to the twice-daily immediate-release (IR) formulation. We conducted 2 randomized, open-label, phase 1 studies in healthy volunteers. Study A characterized single-dose and steady-state PK of tofacitinib XR 11 mg QD and intended to demonstrate equivalence of exposure under single-dose and steady-state conditions to tofacitinib IR 5 mg twice daily. Study B assessed the effect of a high-fat meal on the bioavailability of tofacitinib from the XR formulation. Safety and tolerability were monitored in both studies. In study A (N = 24), the XR and IR formulations achieved time to maximum plasma concentration at 4 hours and 0.5 hours postdose, respectively; terminal half-life was 5.9 hours and 3.2 hours, respectively. Area under plasma concentration-time curve (AUC) and maximum plasma concentration (C max ) after single- and multiple-dose administration were equivalent between the XR and IR formulations. In study B (N = 24), no difference in AUC was observed for fed vs fasted conditions. C max increased by 27% under the fed state. On repeat administration, negligible accumulation (<20%) of systemic exposures was observed for both formulations. Steady state was achieved within 48 hours of dosing with the XR formulation. Tofacitinib administration as an XR or IR formulation was generally well tolerated in these studies. © 2016, The Authors. The Journal of Clinical Pharmacology published by Wiley Periodicals, Inc. on behalf of American College of Clinical Pharmacology. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2006SPIE.6254E..1TG','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2006SPIE.6254E..1TG">Spectrophotometer properties of vein blood plasma in UF-region patients with sharp surgical pathology of abdominal region organs</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Guminestskij, S. G.; Polianski, I. J.; Motrich, A. V.; Grunchuk, F. W. 2006-05-01 It is set that there are two maximums in UF- region absorption of vein blood plasma of a man: at λ = 235 nm and at λ = 280 nm. It is shown that there are the substantial changes of values of the optical density D comparative with controls (for donors) exactly in a maximum at development of sharp surgical diseases of organs of abdominal region λ = 280 nm, in that time as maximum at λ = 235 nm in this plan is not informing. Resulted results of researches of dynamics of changes of optical properties of vein blood plasma in UF- region of patients with pathology of abdominal region organs in after operating period (sharp appendicitis, sharp pancreatitis, intestinal impassability and others like that), which can have the diagnostic value. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19920071521&hterms=difference+principle&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Ddifference%2Bprinciple','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19920071521&hterms=difference+principle&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Ddifference%2Bprinciple">A first-principles model for orificed hollow cathode operation</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Salhi, A.; Turchi, P. J. 1992-01-01 A theoretical model describing orificed hollow cathode discharge is presented. The approach adopted is based on a purely analytical formulation founded on first principles. The present model predicts the emission surface temperature and plasma properties such as electron temperature, number densities and plasma potential. In general, good agreements between theory and experiment are obtained. Comparison of the results with the available related experimental data shows a maximum difference of 10 percent in emission surface temperature, 20 percent in electron temperature and 35 percent in plasma potential. In case of the variation of the electron number density with the discharge current a maximum discrepancy of 36 percent is obtained. However, in the case of the variation with the cathode internal pressure, the predicted electron number density is higher than the experimental data by a maximum factor of 2. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AnGeo..35.1015X','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AnGeo..35.1015X">Occurrence rate of dipolarization fronts in the plasma sheet: Cluster observations</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Xiao, Sudong; Zhang, Tielong; Wang, Guoqiang; Volwerk, Martin; Ge, Yasong; Schmid, Daniel; Nakamura, Rumi; Baumjohann, Wolfgang; Plaschke, Ferdinand 2017-08-01 We investigate the occurrence rate of dipolarization fronts (DFs) in the plasma sheet by taking full advantage of all four Cluster satellites (C1-4) from years 2001 to 2009. In total, we select 466 joint-observation DF events, in which 318, 282, 254, and 236 DFs are observed by C1, C2, C3, and C4, respectively. Our findings are as follows: (1) the maximum occurrence rate is ˜ 15.3 events per day at X ˜ 15 RE in the XY plane, and the average occurrence rate is ˜ 5.4 events per day over the whole observation period; (2) the occurrence rate on the dusk side of the plasma sheet is larger and decreases with increasing BXY/BLobe; (3) the occurrence rate within |Y| < 6 RE increases gradually from X ≈ -19 to -15 RE and then decreases from X ≈ -15 to -10 RE; (4) the occurrence rate when AE > 200 nT is much larger than that when AE < 200 nT, indicating that DFs preferentially occur during high geomagnetic activity. The magnetic pileup and earthward and duskward ion flows could contribute to the increases in the occurrence rate from X ≈ -19 to -15 RE. We suggest that both geomagnetic activity and multiple DFs contribute to the high occurrence rate of the DFs. In addition, the finite length of the DF in the dawn-dusk direction can affect the chance that a satellite observes the DF. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22410465-dual-mode-characteristics-buneman-instability-bounded-slab-plasma','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22410465-dual-mode-characteristics-buneman-instability-bounded-slab-plasma">Dual-mode characteristics of the Buneman instability in a bounded slab plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Hong, Woo-Pyo; Jung, Young-Dae, E-mail: ydjung@hanyang.ac.kr; Department of Applied Physics and Department of Bionanotechnology, Hanyang University, Ansan, Kyunggi-Do 426-791 2015-06-15 The dual-mode characteristics of the Buneman instability are investigated in a slab plasma, including the geometric effects. The dual symmetric and anti-symmetric dispersion modes of the Buneman instability are obtained by the plasma dielectric function with the spectral reflection conditions for the slab geometry. The result shows that the magnitudes of the growth rate for the symmetric mode are always greater than those for the anti-symmetric mode. It is also found that the geometric effect suppresses the position of the maximum growth rate for the Buneman instability in bounded slab plasmas since the maximum conditions for the symmetric and anti-symmetricmore » modes of the Buneman instability are given by 0.60« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015PPCF...57d4005K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015PPCF...57d4005K">Efficient generation of fast neutrons by magnetized deuterons in an optimized deuterium gas-puff z-pinch</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Klir, D.; Shishlov, A. V.; Kokshenev, V. A.; Kubes, P.; Labetsky, A. Yu; Rezac, K.; Cherdizov, R. K.; Cikhardt, J.; Cikhardtova, B.; Dudkin, G. N.; Fursov, F. I.; Garapatsky, A. A.; Kovalchuk, B. M.; Kravarik, J.; Kurmaev, N. E.; Orcikova, H.; Padalko, V. N.; Ratakhin, N. A.; Sila, O.; Turek, K.; Varlachev, V. A. 2015-04-01 Z-pinch experiments with deuterium gas puffs have been carried out on the GIT-12 generator at 3 MA currents. Recently, a novel configuration of a deuterium gas-puff z-pinch was used to accelerate deuterons and to generate fast neutrons. In order to form a homogeneous, uniformly conducting layer at a large initial radius, an inner deuterium gas puff was surrounded by an outer hollow cylindrical plasma shell. The plasma shell consisting of hydrogen and carbon ions was formed at the diameter of 350 mm by 48 plasma guns. A linear mass of the plasma shell was about 5 µg cm-1 whereas a total linear mass of deuterium gas in single or double shell gas puffs was about 100 µg cm-1. The implosion lasted 700 ns and seemed to be stable up to a 5 mm radius. During stagnation, m = 0 instabilities became more pronounced. When a disruption of necks occurred, the plasma impedance reached 0.4 Ω and high energy (>2 MeV) bremsstrahlung radiation together with high energy deuterons were produced. Maximum neutron energies of 33 MeV were observed by axial time-of-flight detectors. The observed neutron spectra could be explained by a suprathermal distribution of deuterons with a high energy tail f≤ft({{E}\\text{d}}\\right)\\propto E\\text{d}-(1.8+/- 0.2) . Neutron yields reached 3.6 × 1012 at a 2.7 MA current. A high neutron production efficiency of 6 × 107 neutrons per one joule of plasma energy resulted from the generation of high energy deuterons and from their magnetization inside plasmas. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19940035206&hterms=VALLADARES&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3DVALLADARES','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19940035206&hterms=VALLADARES&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3DVALLADARES">Modeling polar cap F-region patches using time varying convection</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Sojka, J. J.; Bowline, M. D.; Schunk, R. W.; Decker, D. T.; Valladares, C. E.; Sheehan, R.; Anderson, D. N.; Heelis, R. A. 1993-01-01 Creation of polar cap F-region patches are simulated for the first time using two independent physical models of the high latitude ionosphere. The patch formation is achieved by temporally varying the magnetospheric electric field (ionospheric convection) input to the models. The imposed convection variations are comparable to changes in the convection that result from changes in the B(y) IMF component for southward IMF. Solar maximum-winter simulations show that simple changes in the convection pattern lead to significant changes in the polar cap plasma structuring. Specifically, in winter, as enhanced dayside plasma convects into the polar cap to form the classic tongue-of-ionization the convection changes produce density structures that are indistinguishable from the observed patches. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21077911','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21077911">Bacterial growth kinetics in ACD-A apheresis platelets: comparison of plasma and PAS III storage.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Dumont, Larry J; Wood, Tammara A; Housman, Molly; Herschel, Louise; Brantigan, Barbara; Heber, Cheryl; Houghton, Jaime 2011-05-01 Our objective was to determine the growth kinetics of bacteria in leukoreduced apheresis platelets (LR-AP) in a platelet (PLT) additive solution (PAS; InterSol, Fenwal, Inc.) compared to LR-AP stored in plasma. Hyperconcentrated, double-dose LR-AP were collected from healthy donors with a separator (AMICUS, Fenwal, Inc.). LR-AP were evenly divided, InterSol was added to half (65% InterSol:35% plasma [PAS]), and PLTs in autologous plasma were used for a paired control (PL). Bacteria were inoculated into each LR-AP PAS/PL pair (0.5-1.6 colony-forming units [CFUs]/mL), and bacterial growth was followed for up to 7 days. Time to the end of the lag phase, doubling times, maximum concentration (conc-max), and time to maximum concentration (time-max) were estimated. Streptococcus viridans did not grow to detectable levels in either PAS or PL units. The other bacteria had no significant overall difference in the conc-max (p = 0.47) or time-max (p = 0.7) between PL and PAS LR-AP; PL had a 0.14 hours faster doubling rate (p = 0.023); and PAS had a 4.7 hours shorter lag time (p = 0.016). We observed that five index organisms will grow in LR-AP stored in a 35%:65% ratio of plasma to InterSol where initial bacterial concentrations are 0.5 to 1.6 CFUs/mL. The more rapid initiation of log-phase growth for bacteria within a PAS storage environment resulted in a bacterial concentration up to 4 logs higher in the PAS units compared to the plasma units at 24 hours, but with no difference in the conc-max. This may present an early bacterial detection advantage for PAS-stored PLTs. © 2010 American Association of Blood Banks. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/3902521','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/3902521">[Insulin, glucagon and growth hormone responses during glucose, arginine and insulin tolerance tests in children with hyperthyroidism].</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Kato, T; Matsuura, N; Fujita, H; Fujieda, K; Nohara, Y; Mikami, Y; Abe, K; Fukushima, N 1985-06-20 There are many reports of glucose intolerance in adult patients with hyperthyroidism but few reports of glucose intolerance in hyperthyroid children. In this study, we measured plasma levels of glucose, insulin, glucagon and growth hormone in hyperthyroid children and control subjects by the use of three kinds of tolerance tests: an oral glucose tolerance test, an arginine tolerance test and an insulin tolerance test. In the oral glucose tolerance test, mean fasting glucose levels (79.6 +/- 1.4 mg/dl) rose to maximum levels (157.3 +/- 4.3 mg/dl) at 30 min in hyperthyroid children which were significantly higher than the levels in control subjects (p less than 0.01). The maximum levels of glucose fell slowly and returned to fasting levels at 180 min. In this test, plasma insulin levels increased from basal levels (12.7 +/- 1.9 microU/ml) to maximum levels (120.8 +/- 22.1 microU/ml) at 30 min in the prepubertal age group of hyperthyroidism. On the other hand, in the pubertal age group of hyperthyroidism, maximum levels of insulin were observed at 60 min, but not at 30 min. These maximum levels of insulin of both hyperthyroid age groups were significantly higher than those in the control subjects (p less than 0.05, p less than 0.01 respectively). There was no difference in insulin-glucose ratio at 30 min (delta IRI/delta BG) and insulinogenic index (I.I.) at 0 to 60 min between these two groups of hyperthyroid children and control subjects. However, I.I. at 0 to 120 min and 0 to 180 min decreased significantly in the pubertal age group of hyperthyroidism as compared with those in the control group (p less than 0.05, p less than 0.02 respectively). In the oral glucose tolerance test, plasma glucagon levels decreased from basal levels (74.1 +/- 4.3 pg/ml) to minimum levels (36.4 +/- 4.7 pg/ml) at 90 min in hyperthyroidism, which were significantly lower than those in the controls (p less than 0.05). However, there was no difference in -epsilon delta IRG/epsilon delta BG (cumulative glucagon response/cumulative glucose response) between the subjects with hyperthyroidism and the controls. On the other hand, lower responses of blood glucose, insulin, glucagon and growth hormone to arginine were observed in subjects with hyperthyroidism than in the controls. Moreover in the insulin tolerance test, there was no difference in glucagon and growth hormone response between the subjects with hyperthyroidism and the controls. Thus our conclusions are as follows: A marked increase in blood glucose after oral glucose load was observed in spite of normal insulin-glucose ratio in hyperthyroid children, suggesting the existence of peripheral insulin resistance.(ABSTRACT TRUNCATED AT 400 WORDS) </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA188058','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA188058">Upper-Thermospheric Observations and Neutral-Gas Dynamics at High Latitudes During Solar Maximum.</a> <a target="_blank" rel="noopener noreferrer" href="http://www.dtic.mil/">DTIC Science & Technology</a> 1987-01-01 quickly, allowing the higher-latitude lines to spring back in towards the Earth ( Vallance -Jones, 1974). This also compresses and heats the plasma on high... Richards , and D. G. Torr. A new determination of the ultraviolet heating efficiency of the thermosphere. J. Geophys. Res., 85, 6819 - 6826, 1980b. Torr...M. R., D. G. Torr, and P. G. Richards . The solar ultraviolet heating efficiency of the midlatitude thermosphere. Geophys. Res. Lett., 7, 373 - 376 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/4018678-effects-ionizing-radiation-arylesterase-cholinesterase','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/4018678-effects-ionizing-radiation-arylesterase-cholinesterase">Effects of Ionizing Radiation on Arylesterase and Cholinesterase.</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Augustinsson, Klas-Bertil; Jonsson, Gunnel; Sparrman, Berndt 1961-01-01 The effects of Co 60 gamma radiation on arylesterase and cholinesterase of human blood plasma were compared using solid preparations of purified enzymes containing various amounts of water. In the case of cholinesterase a water content of 12% exerted maximum protection against irradiation. Such a protection by water was not observed with arylesterase. Finally, in aqueous solutions cholinesterase was more resistant to irradiation by gamma rays than was arylesterase when irradiation was performed in an atmosphere of nitrogen. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li class="active">11</li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_12" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li class="active">12</li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="221"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3717336','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3717336">Identification of Recent Cannabis Use: Whole-Blood and Plasma Free and Glucuronidated Cannabinoid Pharmacokinetics following Controlled Smoked Cannabis Administration</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Schwope, David M.; Karschner, Erin L.; Gorelick, David A.; Huestis, Marilyn A. 2013-01-01 BACKGROUND Δ9-Tetrahydrocannabinol (THC) is the most frequently observed illicit drug in investigations of accidents and driving under the influence of drugs. THC-glucuronide has been suggested as a marker of recent cannabis use, but there are no blood data following controlled THC administration to test this hypothesis. Furthermore, there are no studies directly examining whole-blood cannabinoid pharmacokinetics, although this matrix is often the only available specimen. METHODS Participants (9 men, 1 woman) resided on a closed research unit and smoked one 6.8% THC cannabis cigarette ad libitum. We quantified THC, 11-hydroxy-THC (11-OH-THC), 11-nor-9-carboxy-THC (THCCOOH), cannabidiol (CBD), cannabinol (CBN), THC-glucuronide and THCCOOH-glucuronide directly in whole blood and plasma by liquid chromatography/ tandem mass spectrometry within 24 h of collection to obviate stability issues. RESULTS Median whole blood (plasma) observed maximum concentrations (Cmax) were 50 (76), 6.4 (10), 41 (67), 1.3 (2.0), 2.4 (3.6), 89 (190), and 0.7 (1.4) μg/L 0.25 h after starting smoking for THC, 11-OH-THC, THCCOOH, CBD, CBN, and THCCOOH-glucuronide, respectively, and 0.5 h for THC-glucuronide. At observed Cmax, whole-blood (plasma) detection rates were 60% (80%), 80% (90%), and 50% (80%) for CBD, CBN, and THC-glucuronide, respectively. CBD and CBN were not detectable after 1 h in either matrix (LOQ 1.0 μg/L). CONCLUSIONS Human whole-blood cannabinoid data following cannabis smoking will assist whole blood and plasma cannabinoid interpretation, while furthering identification of recent cannabis intake. PMID:21836075 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23865886','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23865886">Pharmacokinetics and distribution of ceftazidime to milk after intravenous and intramuscular administration to lactating female dromedary camels (Camelus dromedarius).</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Goudah, Ayman M; Hasabelnaby, Sherifa M 2013-08-01 To determine the plasma disposition kinetics, absolute bioavailability, and milk concentrations of ceftazidime in healthy lactating female dromedary camels (Camelus dromedarius) following IV and IM administration of a single dose of 10 mg/kg (4.5 mg/lb). Prospective crossover study. 8 healthy adult lactating female dromedary camels. Camels received ceftazidime (10 mg/kg) IV and IM in a crossover study design with a 15-day washout period between treatments. Plasma and milk samples were collected at predetermined times for 48 hours after drug administration and analyzed by use of high-performance liquid chromatography. A 2-compartment open model best represented the plasma concentration-versus-time data after IV and IM administration of ceftazidime to camels. Plasma ceftazidime concentrations decreased biexponentially after IV administration with mean distribution and elimination half-lives of 0.3 hours and 2.85 hours, respectively. After IM administration, the mean maximum plasma concentration of ceftazidime was 32.43 μg/mL (1.21 hours after administration), mean elimination half-life was 3.20 hours, mean residence time was 4.84 hours, and mean systemic bioavailability was 93.72%. Distribution of ceftazidime from plasma to milk was rapid and extensive as indicated by the ratio of the area under the milk concentration-versus-time curve to the area under the plasma concentration-versus-time curve and the ratio of the maximum milk concentration to the maximum plasma concentration of ceftazidime after IV and IM administration. Results suggested that ceftazidime may be a useful treatment for female camels with mastitis caused by susceptible microorganisms. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JPhD...49m5202A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JPhD...49m5202A">Ozone synthesis improves by increasing number density of plasma channels and lower voltage in a nonthermal plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Arif Malik, Muhammad; Hughes, David 2016-04-01 Improvements in ozone synthesis from air and oxygen by increasing the number density of plasma channels and lower voltage for the same specific input energy (SIE) were explored in a nonthermal plasma based on a sliding discharge. The number of plasma channels and energy per pulse increased in direct proportion to the increase in the effective length of the anode (the high voltage electrode). Decreasing the discharge gap increased the energy per pulse for the same length and allowed the installation of more electrode pairs in the same space. It allowed the increase of the number of plasma channels in the same space to achieve the same SIE at a lower peak voltage with less energy per plasma channel. The ozone concentration gradually increased to ~1500 ppmv (140 to 50 g kWh-1) from air and to ~6000 ppmv (400 to 200 g kWh-1) from oxygen with a gradual increase in the SIE to ~200 J L-1, irrespective of the variations in electrode geometry, applied voltage or flow rate of the feed gas. A gradual increase in SIE beyond 200 J L-1 gradually increased the ozone concentration to a certain maximum value followed by a decline, but the rate of increase and the maximum value was higher for the greater number of plasma channels and lower peak voltage combination. The maximum ozone concentration was ~5000 ppmv (~30 g kWh-1) from air and ~22 000 ppmv (~80 g kWh-1) from oxygen. The results are explained on the basis of characteristics of the plasma and ozone synthesis mechanism. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20496932','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20496932">DC water plasma at atmospheric pressure for the treatment of aqueous phenol.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Yuan, Min-Hao; Narengerile; Watanabe, Takayuki; Chang, Ching-Yuan 2010-06-15 This study investigated the decomposition of aqueous phenol by direct current (DC) water plasma. The operation of DC water plasma was carried out in the absence of inert gases or air injected and cooling-controlled and pressure-controlled devices. The results indicated that 1 mol.% (52.8 g L(-1)) phenol was drastically decomposed by DC water plasma touch with energy efficiencies of 1.9 x 10(-8)-2.2 x 10(-8) mol J(-1). Also, the value of chemical oxygen demand (COD) was reduced from 100 000 mg L(-1) down to 320 mg L(-1) over a short retention time. The maximum decomposition rate of the COD was 258 mg COD min(-1) for the arc power of 0.91 kW. In the effluent analysis, H(2) (63-68%), CO (3.6-6.3%), CO(2) (25.3-28.1%) were major products in the exhaust gas and CH(4), C(2)H(2), HCOOH and C(6)H(6) in trace level. Further, HCOOH and HCHO were observed in the liquid effluents. Within the current paper, the results indicated that the DC water plasma torch is capable of an alternative green technology for phenol wastewater containing high COD. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016APS..DPPCI3003S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016APS..DPPCI3003S">Increasing Plasma Parameters using Sheared Flow Stabilization of a Z-Pinch</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Shumlak, Uri 2016-10-01 Recent experiments on the ZaP Flow Z-Pinch at the University of Washington have been successful in compressing the plasma column to smaller radii, producing the predicted increases in plasma density (1018 cm-3), temperature (200 eV), and magnetic fields (4 T), while maintaining plasma stability for many Alfven times (over 40 μs) using sheared plasma flows. These results indicate the suitability of the device as a discovery science platform for astrophysical and high energy density plasma research, and keeps open a possible path to achieving burning plasma conditions in a compact fusion device. Long-lived Z-pinch plasmas have been produced with dimensions of 1 cm radius and 100 cm long that are stabilized by sheared axial flows for over 1000 Alfven radial transit times. The observed plasma stability is coincident with the presence of a sheared flow as measured by time-resolved multi-chord ion Doppler spectroscopy applied to impurity ion radiation. These measurements yield insights into the evolution of the velocity profile and show that the stabilizing behavior of flow shear agrees with theoretical calculations and 2-D MHD computational simulations. The flow shear value, extent, and duration are shown to be consistent with theoretical models of the plasma viscosity, which places a design constraint on the maximum axial length of a sheared flow stabilized Z-pinch. Measurements of the magnetic field topology indicate simultaneous azimuthal symmetry and axial uniformity along the entire 100 cm length of the Z-pinch plasma. Separate control of plasma acceleration and compression have increased the accessible plasma parameters and have generated stable plasmas with radii below 0.5 cm, as measured with a high resolution digital holographic interferometer. This work was supported by Grants from U.S. DOE, NNSA, and ARPA-E. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28727139','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28727139">Effect of solvent/detergent-treated pooled plasma on fibrinolysis in reconstituted whole blood.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Saadah, Nicholas H; van der Meer, Pieter F; Brinkman, Herm Jan M; de Korte, Dirk; Bontekoe, Ido J; Korsten, Herbert H; Middelburg, Rutger A; van der Bom, Johanna G; Schipperus, Martin R 2017-10-01 Hyperfibrinolysis has been observed in patients heavily transfused with solvent/detergent-treated pooled plasma (S/D plasma). We compared coagulation and fibrinolytic variables in blood containing S/D plasma with blood containing fresh-frozen plasma (FFP), with and without α2-antiplasmin or tranexamic acid (TXA) supplementation. Whole blood samples were reconstituted from red blood cells, platelet (PLT) concentrates, and varying mixtures of FFP and S/D plasma. Hematocrit and PLT count of reconstituted whole blood samples were varied. For a subset of runs, α2-antiplasmin or TXA was added to S/D plasma whole blood samples. Thromboelastography (TEG) analysis was performed to assess 50% clot lysis time (CLT 50% ), maximum amplitude (MA), and initial clotting time (R-time). The change in CLT 50% of whole blood as the plasma compartment transitions from FFP to S/D plasma was -52% (95% confidence interval [CI], -60% to -45%; p < 0.001). PLT count strengthened the effect, leading to an additional change in CLT 50% of -8% (95% CI, -14% to -2%; p = 0.012) as PLT count increased from 10 × 10 9 to 150 × 10 9 /L. MA and R-time were not associated with fraction of S/D plasma in whole blood. α2-Antiplasmin and TXA restored clot lysis time in S/D plasma whole blood. Whole blood with S/D plasma has shorter clot lysis times in vitro compared to whole blood with FFP. α2-Antiplasmin and TXA restore clot lysis time of S/D plasma whole blood to that of FFP whole blood. Clinicians should be aware of the decreased clot lysis time associated with S/D plasma transfusion. © 2017 AABB. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22220641-study-maximum-power-transfer-condition-inductively-coupled-plasma-using-transformer-circuit-model','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22220641-study-maximum-power-transfer-condition-inductively-coupled-plasma-using-transformer-circuit-model">A study on the maximum power transfer condition in an inductively coupled plasma using transformer circuit model</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Kim, Young-Do; Lee, Hyo-Chang; Chung, Chin-Wook Correlations between the external discharge parameters (the driving frequency ω and the chamber dimension R) and plasma characteristics (the skin depth δ and the electron-neutral collision frequency ν{sub m}) are studied using the transformer circuit model [R. B. Piejak et al., Plasma Sources Sci. Technol. 1, 179 (1992)] when the absorbed power is maximized in an inductively coupled plasma. From the analysis of the transformer circuit model, the maximum power transfer conditions, which depend on the external discharge parameters and the internal plasma characteristics, were obtained. It was found that a maximum power transfer occurs when δ≈0.38R for the dischargemore » condition at which ν{sub m}/ω≪1, while it occurs when δ≈√(2)√(ω/ν{sub m})R for the discharge condition at which ν{sub m}/ω≫1. The results of this circuit analysis are consistent with the stable last inductive mode region of an inductive-to-capacitive mode transition [Lee and Chung, Phys. Plasmas 13, 063510 (2006)], which was theoretically derived from Maxwell's equations. Our results were also in agreement with the experimental results. From this work, we demonstrate that a simple circuit analysis can be applied to explain complex physical phenomena to a certain extent.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24593506','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24593506">Plasma studies of the permanent magnet electron cyclotron resonance ion source at Peking University.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Ren, H T; Peng, S X; Xu, Y; Zhao, J; Lu, P N; Chen, J; Zhang, A L; Zhang, T; Guo, Z Y; Chen, J E 2014-02-01 At Peking University (PKU) we have developed several 2.45 GHz Permanent Magnet Electron Cyclotron Resonance ion sources for PKUNIFTY, SFRFQ, Coupled RFQ&SFRFQ, and Dielectric-Wall Accelerator (DWA) projects (respectively, 50 mA of D(+), 10 mA of O(+), 10 mA of He(+), and 50 mA of H(+)). In order to improve performance of these ion sources, it is necessary to better understand the principal factors that influence the plasma density and the atomic ion fraction. Theoretical analysis about microwave transmission and cut-off inside the discharge chamber were carried out to study the influence of the discharge chamber diameters. As a consequence, experimental studies on plasma density and ion fraction with different discharge chamber sizes have been carried out. Due to the difficulties in measuring plasma density inside the discharge chamber, the output beam current was measured to reflect the plasma density. Experimental results show that the plasma density increases to the maximum and then decreases significantly as the diameter changed from 64 mm to 30 mm, and the atomic ion fraction has the same tendency. The maximum beam intensity was obtained with the diameter of 35 mm, but the maximum atomic ion fraction with a diameter of 40 mm. The experimental results are basically accordant with the theoretical calculation. Details are presented in this paper. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16256662','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16256662">Improvement of interfacial adhesion and nondestructive damage evaluation for plasma-treated PBO and Kevlar fibers/epoxy composites using micromechanical techniques and surface wettability.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Park, Joung-Man; Kim, Dae-Sik; Kim, Sung-Ryong 2003-08-15 Comparison of interfacial properties and microfailure mechanisms of oxygen-plasma treated poly(p-phenylene-2,6-benzobisoxazole (PBO, Zylon) and poly(p-phenylene terephthalamide) (PPTA, Kevlar) fibers/epoxy composites were investigated using a micromechanical technique and nondestructive acoustic emission (AE). The interfacial shear strength (IFSS) and work of adhesion, Wa, of PBO or Kevlar fiber/epoxy composites increased with oxygen-plasma treatment, due to induced hydrogen and covalent bondings at their interface. Plasma-treated Kevlar fiber showed the maximum critical surface tension and polar term, whereas the untreated PBO fiber showed the minimum values. The work of adhesion and the polar term were proportional to the IFSS directly for both PBO and Kevlar fibers. The microfibril fracture pattern of two plasma-treated fibers appeared obviously. Unlike in slow cooling, in rapid cooling, case kink band and kicking in PBO fiber appeared, whereas buckling in the Kevlar fiber was observed mainly due to compressive and residual stresses. Based on the propagation of microfibril failure toward the core region, the number of AE events for plasma-treated PBO and Kevlar fibers increased significantly compared to the untreated case. The results of nondestructive AE were consistent with microfailure modes. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/17825891','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/17825891">Exposure of infants to budesonide through breast milk of asthmatic mothers.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Fält, Anette; Bengtsson, Thomas; Kennedy, Britt-Marie; Gyllenberg, Ann; Lindberg, Bengt; Thorsson, Lars; Stråndgarden, Kerstin 2007-10-01 Maintenance treatment with inhaled corticosteroids is often required for asthmatic nursing women. Data on the transfer of inhaled corticosteroids from plasma to breast milk and the subsequent exposure of the breast-feeding infant has been unavailable. We sought to assess budesonide concentrations in milk and plasma of asthmatic nursing women receiving maintenance treatment with the Pulmicort Turbuhaler and estimate the exposure of their breast-fed infants. Milk and plasma samples were collected up to 8 hours after dosing from 8 mothers receiving budesonide maintenance treatment (200 or 400 microg twice daily). Pharmacokinetic parameters were calculated from budesonide milk and plasma concentrations. Infant exposure was estimated based on average milk budesonide concentrations. A single blood sample was obtained from 5 infants close to expected infant maximum concentration. Budesonide concentrations in milk reflected those in maternal plasma, supporting passive diffusion of budesonide between plasma and milk, and was always lower than that in plasma. The mean milk/plasma ratio was 0.46. The estimated daily infant dose was 0.3% of the daily maternal dose for both dose levels, and the average plasma concentration in infants was estimated to be 1/600th of the concentrations observed in maternal plasma, assuming complete infant oral bioavailability. Budesonide concentrations in infant plasma samples were all less than the limit of quantification. Maintenance treatment with inhaled budesonide (200 or 400 microg twice daily) in asthmatic nursing women results in negligible systemic exposure to budesonide in breast-fed infants. These data support continued use of inhaled budesonide during breast-feeding. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3605229','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3605229">Lack of reliability of nanotechnology in the of free plasma DNA in samples of patients with prostate cancer</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> 2013-01-01 Background Several studies seek biological markers that give diagnostic and degree of tumor development. The aim of this study was to validate the determination of plasma DNA using nanotechnology (Nanovue™-NV) in samples of 80 patients with prostate cancer. Methods Blood samples of 80 patients of the Urology Ambulatory of Faculdade de Medicina do ABC with prostate cancer confirmed by anatomical-pathology criteria were analyzed. DNA extraction was performed using a GFX TM kit (Amersham Pharmacia Biotech, Inc, USA) following the adapted protocol. Plasma was subjected to centrifugation. Results There was a big difference between the first and the second value obtained by NanoVue Only two samples had no differences between duplicates. Maximum difference between duplicates was 38 μg/mL. Average variation between 51 samples was 10.29 μg/mL, although 21 samples had differences above this average. No correlation was observed between pDNA obtained by traditional spectrophotometry and by nanotechnology. Conclusion Determination of plasma DNA by nanotechnology was not reproducible. PMID:23311763 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFMSH53B..02C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFMSH53B..02C">STEREO Observations of Waves in the Ramp Regions of Interplanetary Shocks</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Cohen, Z.; Breneman, A. W.; Cattell, C. A.; Davis, L.; Grul, P.; Kersten, K.; Wilson, L. B., III 2017-12-01 Determining the role of plasma waves in providing energy dissipation at shock waves is of long-standing interest. Interplanetary (IP) shocks serve as a large database of low Mach number shocks. We examine electric field waveforms captured by the Time Domain Sampler (TDS) on the STEREO spacecraft during the ramps of IP shocks, with emphasis on captures lasting 2.1 seconds. Previous work has used captures of shorter duration (66 and 131 ms on STEREO, and 17 ms on WIND), which allowed for observation of waves with maximum (minimum) frequencies of 125 kHz (15 Hz), 62.5 kHz (8 Hz), and 60 kHz (59 Hz), respectively. The maximum frequencies are comparable to 2-8 times the plasma frequency in the solar wind, enabling observation of Langmuir waves, ion acoustic, and some whistler-mode waves. The 2 second captures resolve lower frequencies ( few Hz), which allows us to analyze packet structure of the whistler-mode waves and some ion acoustic waves. The longer capture time also improves the resolvability of simultaneous wave modes and of waves with frequencies on the order of 10s of Hz. Langmuir waves, however, cannot be identified at this sampling rate, since the plasma frequency is usually higher than 3.9 kHz. IP shocks are identified from multiple databases (Helsinki heliospheric shock database at http://ipshocks.fi, and the STEREO level 3 shock database at ftp://stereoftp.nascom.nasa.gov/pub/ins_data/impact/level3/). Our analysis focuses on TDS captures in shock ramp regions, with ramp durations determined from magnetic field data taken at 8 Hz. Software is used to identify multiple wave modes in any given capture and classify waves as Langmuir, ion acoustic, whistler, lower hybrid, electron cyclotron drift instability, or electrostatic solitary waves. Relevant frequencies are determined from density and magnetic field data collected in situ. Preliminary results suggest that large amplitude (≥ 5 mV/m) ion acoustic waves are most prevalent in the ramp, in agreement with Wilson, et al. Other modes are also observed. Statistical results will be presented and compared with previous studies and theoretical predictions. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2001JNuM..290..658L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2001JNuM..290..658L">Investigation of the hydrogen fluxes in the plasma edge of W7-AS during H-mode discharges</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Langer, U.; Taglauer, E.; Fischer, R.; W7-AS Team 2001-03-01 In the stellarator W7-AS the H-mode is characterized by an edge transport barrier which is localized within a few centimeters inside the separatrix. The corresponding L-H transition shows well-known features such as the steepening of the temperature and density profiles in the region of the separatrix. With a so-called sniffer probe the temporal development of the hydrogen and deuterium fluxes has been studied in the plasma edge during different H-mode discharges with deuterium gas puffing. Prior to the transition a significant reduction of the deuterium and also the hydrogen fluxes can be observed. This fact confirms the assumption that the steepening of the density profiles starts at the outermost edge of the plasma. Moreover, sniffer probe measurements in the plasma edge could therefore identify a precursor for the L-H transition. The analysis of the hydrogen neutral gases shows a distinct change of the hydrogen isotope ratio during the transition. This observation is in agreement with the change in the particle fluxes onto the targets and can also be seen in the reduced H α signals from the limiters. It is further demonstrated that significant improvement in the time resolution of the measured data can be obtained by deconvolution of the data with the apparatus function using Bayesian probability theory and the Maximum Entropy method with adaptive kernels. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22395719-enhancement-mechanism-thin-plasma-layer-antenna-radiation','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22395719-enhancement-mechanism-thin-plasma-layer-antenna-radiation">The enhancement mechanism of thin plasma layer on antenna radiation</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Wang, Chunsheng, E-mail: wangcs@hit.edu.cn; Jiang, Binhao; Li, Xueai A model of plasma-antenna is carried out to study the radiation enhancement mechanism of antenna covered by thin plasma layer. The results show when the radiation intensity achieves maximum, a region of equal electric field is formed due to the reflection of electric field at the interface of plasma and air. The plasma layer acted as an extension of the antenna. Furthermore, the shape of plasma layer is changed to verify the effect of plasma boundary on antenna radiation. The study shows the effect of thin plasma layer on electromagnetic field and provides a type of plasma antenna. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1995AdSpR..15...37A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1995AdSpR..15...37A">Variations in iron and calcium abundances during solar flares</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Antonucci, E.; Martin, R. 1995-07-01 Evidence for variations in iron and calcium abundances during the impulsive phase of solar flares has been obtained by analyzing the Ca XIX and Fe XXV spectra, detected with the Bent Crystal Spectrometer of the Solar Maximum Mission. The plasma thermal conditions have been investigated by considering different temperature indicators: namely, the temperatures TCa and TFe, derived from the intensity ratios of the dielectronic recombination satellites to the resonance line, and the temperature TCaFe, calculated from the ratio of the resonance lines of Ca XIX and Fe XXV, which is also depending on the Fe/Ca abundance ratio. The observed values of TCa and TFe can be ascribed to the specific characteristics of the plasma therma distribution, the corresponding values of TCaFe can be explained by allowing also for variations in the Fe/Ca abundance ratio relative to the photospheric ratio by a factor within 0.2 and 2.4. According to the observed abundance variations, the events analyzed can be divided in Ca-rich and Fe-rich flares. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/11461406','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/11461406">Observation of ultrahigh-energy electrons by resonance absorption of high-power microwaves in a pulsed plasma.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Rajyaguru, C; Fuji, T; Ito, H; Yugami, N; Nishida, Y 2001-07-01 The interaction of high power microwave with collisionless unmagnetized plasma is studied. Investigation on the generation of superthermal electrons near the critical layer, by the resonance absorption phenomenon, is extended to very high microwave power levels (eta=E(2)(0)/4 pi n(e)kT(e) approximately 0.3). Here E0, n(e), and T(e) are the vacuum electric field, electron density, and electron temperature, respectively. Successive generation of electron bunches having maximum energy of about 2 keV, due to nonlinear wave breaking, is observed. The electron energy epsilon scales as a function of the incident microwave power P, according to epsilon proportional to P0.5 up to 250 kW. The two-dimensional spatial distribution of high energy electrons reveals that they are generated near the critical layer. However, the lower energy component is again produced in the subcritical density region indicating the possibility of other electron heating mechanisms. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017PlPhR..43..196S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017PlPhR..43..196S">Measurement of ion beam angular distribution at different helium gas pressures in a plasma focus device by large-area polycarbonate detectors</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Sohrabi, M.; Habibi, M.; Ramezani, V. 2017-02-01 The paper presents an experimental study and analysis of full helium ion density angular distributions in a 4-kJ plasma focus device (PFD) at pressures of 10, 15, 25, and 30 mbar using large-area polycarbonate track detectors (PCTDs) (15-cm etchable diameter) processed by 50-Hz-HV electrochemical etching (ECE). Helium ion track distributions at different pressures, in particular, at the main axis of the PFD are presented. Maximum ion track density of 4.4 × 104 tracks/cm2 was obtained in the PCTD placed 6 cm from the anode. The ion distributions for all pressures applied are ring-shaped, which is possibly due to the hollow cylindrical copper anode used. The large-area PCTD processed by ECE proves, at the present state-of-theart, a superior method for direct observation and analysis of ion distributions at a glance with minimum efforts and time. Some observations of the ion density distributions at different pressures are reported and discussed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25366540','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25366540">Plasma concentration-dependent suppression of endogenous hydrocortisone in the horse after intramuscular administration of dexamethasone-21-isonicotinate.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Ekstrand, C; Bondesson, U; Gabrielsson, J; Hedeland, M; Kallings, P; Olsén, L; Ingvast-Larsson, C 2015-06-01 Detection times and screening limits (SL) are methods used to ensure that the performance of horses in equestrian sports is not altered by drugs. Drug concentration-response relationship and knowledge of concentration-time profiles in both plasma and urine are required. In this study, dexamethasone plasma and urine concentration-time profiles were investigated. Endogenous hydrocortisone plasma concentrations and their relationship to dexamethasone plasma concentrations were also explored. A single dose of dexamethasone-21-isonicotinate suspension (0.03 mg/kg) was administered intramuscularly to six horses. Plasma was analysed for dexamethasone and hydrocortisone and urine for dexamethasone, using UPLC-MS/MS. Dexamethasone was quantifiable in plasma for 8.3 ± 2.9 days (LLOQ: 0.025 μg/L) and in urine for 9.8 ± 3.1 days (LLOQ: 0.15 μg/L). Maximum observed dexamethasone concentration in plasma was 0.61 ± 0.12 μg/L and in urine 4.2 ± 0.9 μg/L. Terminal plasma half-life was 38.7 ± 19 h. Hydrocortisone was significantly suppressed for 140 h. The plasma half-life of hydrocortisone was 2.7 ± 1.3 h. Dexamethasone potency, efficacy and sigmoidicity factor for hydrocortisone suppression were 0.06 ± 0.04 μg/L, 0.95 ± 0.04 and 6.2 ± 4.6, respectively. Hydrocortisone suppression relates to the plasma concentration of dexamethasone. Thus, determination of irrelevant plasma concentrations and SL is possible. Future research will determine whether hydrocortisone suppression can be used as a biomarker of the clinical effect of dexamethasone. © 2014 John Wiley & Sons Ltd. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010JFuE...29..307S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010JFuE...29..307S">Study the Output Characteristics of a 90 kJ Filippove-Type Plasma Focus</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Sadat Kiai, S. M.; Talaei, A.; Adlparvar, S.; Zirak, A.; Elahi, M.; Safarian, A.; Farhangi, S.; Alhooie, S.; Dabirzadeh, A. A.; Khalaj, M. M.; Mahlooji, M. S.; Talaei, M.; KaKaei, S.; Sheibani, S.; Kashani, A.; Zahedi, F. 2010-08-01 The output characteristics of a Filippove-Type plasma focus "Dena" (288 μF, 25 kV, 90 kJ) is numerically investigated by considering the voltage, current, current derivative, and maximum current as a function of capacitor bank energy in the constant Argon gas pressure and compared to the experiment. It is shown that increase on the bank energy leads to the increment on the maximum current and decrement on the pinch time. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22614149-investigation-helicon-discharge-plasma-parameters-hybrid-rf-plasma-system','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22614149-investigation-helicon-discharge-plasma-parameters-hybrid-rf-plasma-system">Investigation of the helicon discharge plasma parameters in a hybrid RF plasma system</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Aleksandrov, A. F.; Petrov, A. K., E-mail: alpetrov57@gmail.com; Vavilin, K. V. 2016-03-15 Results of an experimental study of the helicon discharge plasma parameters in a prototype of a hybrid RF plasma system equipped with a solenoidal antenna are described. It is shown that an increase in the external magnetic field leads to the formation of a plasma column and a shift of the maximum ion current along the discharge axis toward the bottom flange of the system. The shape of the plasma column can be controlled via varying the configuration of the magnetic field. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li class="active">12</li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_13" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li class="active">13</li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="241"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018LaPhy..28d5405I','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018LaPhy..28d5405I">Influence of dispersion stretching of ultrashort UV laser pulse on the critical power for self-focusing</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Ionin, A. A.; Mokrousova, D. V.; Piterimov, D. A.; Seleznev, L. V.; Sinitsyn, D. V.; Sunchugasheva, E. S. 2018-04-01 The critical power for self-focusing in air for ultrashort ultraviolet laser pulses, stretched due to dispersion from 90 to 730 fs, was experimentally measured. It was shown that the pulse duration enhancement due to its propagation in condensed media leads to an almost linear decrease in the critical power for self-focusing. It was also observed that when the pulse peak power exceeds the critical one, the maximum of linear plasma distribution along the ultraviolet laser filament does not shift in the direction opposite to the laser pulse propagation, as observed for infrared laser filaments, but remains at the geometrical focus. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18080308','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18080308">Mechanical and chemical characteristics of an autologous glue.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> De Somer, Filip; Delanghe, Joris; Somers, Pamela; Debrouwere, Maarten; Van Nooten, Guido 2008-09-15 The study evaluates the mechanical and chemical characteristics of autologous surgical glue made by mixing ultrafiltered plasma with glutaraldehyde (GTA). Human albumin 200 g/L mixed with different concentrations of GTA (25, 50, 75, or 100 g/L) was used as a single protein set-up for testing tensile strength, elasticity, and rate of crosslinking. Subsequently, ultrafiltered canine or human plasma to obtain autologous glue replaced human albumin. BioGlue, a surgical glue, and Tissucol Duo, a fibrin sealant, were used as controls. Tensile strength of human albumin 200 g/L mixed with 75 g/L GTA is 825 +/- 109 N versus 672 +/- 167 N for BioGlue. Ultrafiltered canine plasma showed a maximum tensile strength of 634 +/- 137 N when mixed with GTA 75 g/L. For human plasma, the maximum tensile strength of 436 +/- 69 N was reached after mixing with GTA 25 g/L. Autologous glue had a higher elasticity of 144 +/- 66 N versus 322 +/- 104 N for BioGlue at maximum load. Autologous glues for vascular repair can be easily prepared out of the patient's plasma. The optimal characteristics, compared to BioGlue, are obtained for ultrafiltered canine and human plasma by mixing with a GTA concentration of 50-75 g/L and 25-50 g/L, respectively. The autologous glue will exert less tensile strength than BioGlue but has a better compliance. In case where no plasma can obtained from the patient, mixing human albumin 200 g/L with GTA 75 g/L can be an alternative to BioGlue. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016MPLB...3030002K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016MPLB...3030002K">The quantum pinch effect in semiconducting quantum wires: A bird’s-eye view</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kushwaha, Manvir S. 2016-01-01 Those who measure success with culmination do not seem to be aware that life is a journey not a destination. This spirit is best reflected in the unceasing failures in efforts for solving the problem of controlled thermonuclear fusion for even the simplest pinches for over decades; and the nature keeps us challenging with examples. However, these efforts have permitted researchers the obtention of a dense plasma with a lifetime that, albeit short, is sufficient to study the physics of the pinch effect, to create methods of plasma diagnostics, and to develop a modern theory of plasma processes. Most importantly, they have impregnated the solid state plasmas, particularly the electron-hole plasmas in semiconductors, which do not suffer from the issues related with the confinement and which have demonstrated their potential not only for the fundamental physics but also for the device physics. Here, we report on a two-component, cylindrical, quasi-one-dimensional quantum plasma subjected to a radial confining harmonic potential and an applied magnetic field in the symmetric gauge. It is demonstrated that such a system, as can be realized in semiconducting quantum wires, offers an excellent medium for observing the quantum pinch effect at low temperatures. An exact analytical solution of the problem allows us to make significant observations: Surprisingly, in contrast to the classical pinch effect, the particle density as well as the current density display a determinable maximum before attaining a minimum at the surface of the quantum wire. The effect will persist as long as the equilibrium pair density is sustained. Therefore, the technological promise that emerges is the route to the precise electronic devices that will control the particle beams at the nanoscale. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014AGUFMSM51E4276P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014AGUFMSM51E4276P">Solar Cycle Changes in the Position of the Intermediate Transition in the Venus Ionosheath.</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Perez De Tejada, H. A.; Lundin, R. N. A.; Durand-Manterola, H. J.; Reyes-Ruiz, M.; Barabash, S.; Zhang, T.; Sauvaud, J. A. 2014-12-01 Measurements conducted with the ASPERA plasma probe and the magnetometer of the Venus Express (VEX) spacecraft in orbits that probed by the midnight plane within the Venus wake show the presence of a sharp plasma transition outside the region where enhanced fluxes of planetary ions are observed. That transition agrees with a feature reported earlier [1] from the VEX electron measurements and that is now also characterized by a sharp change in the speed and density of the solar wind H+ ions [2]. From the analysis of the plasma data of 10 VEX orbits in two different time periods (August 2006 and September 2009) it is possible to derive the position of the VEX spacecraft at the time when the plasma transition is observed in all 10 orbits. The data show a collection of different distances downstream from Venus where the plasma transition is detected and that are grouped for each time period. As a whole the X-distance on the sun-Venus line downstream from the planet for each of the 5 orbits corresponding to the August 2006 time period is smaller than that corresponding to the 5 orbits of the September 2009 time period. The average distance difference between both sets of data points is nearly one half planetary radius thus leading to two different groups in their distribution. The position of the plasma transition downstream from Venus will vary along the solar cycle being displaced to regions that extend farther away from the inner wake under solar maximum conditions. [1] Pérez-de-Tejada, H.et al., JGR, 116, JA015216, 2011. [2] Pérez-de-Tejada, H.et al., JGR, 118, JA019029, 2013. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26918286','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26918286">Effect of high-fat meal intake on the pharmacokinetic profile of ivermectin in Japanese patients with scabies.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Miyajima, Atsushi; Hirota, Takashi; Sugioka, Akihito; Fukuzawa, Masao; Sekine, Mari; Yamamoto, Yosuke; Yoshimasu, Takashi; Kigure, Akira; Anata, Taichi; Noguchi, Wataru; Akagi, Keita; Komoda, Masayo 2016-09-01 Ivermectin (IVM) is used as an anthelmintic agent in many countries. To evaluate the effect of high-fat (HF) meal intake on the pharmacokinetics of IVM, a clinical trial was conducted in Japanese patients with scabies. The patients were administrated Stromectol(®) tablets in the fasted state, and after 1 week they were also administrated it after a HF meal (fed state). After the administration, IVM concentrations in plasma and the stratum corneum were determined. The geometric mean of fed/fasted ratio of area under IVM concentration-time curve (AUC) in plasma was 1.25 (90% confidence interval, 1.09-1.43), suggesting the tendency to increased absorption after a HF meal. The fed/fasted ratio of the maximum IVM concentration in the stratum corneum was well correlated with that in plasma. In addition, no serious adverse events were observed during the trial, while a mild increase of aspartate aminotransferase and alanine aminotransferase activity in plasma was observed under the fed state in two patients. The mean AUC of IVM in plasma of those two patients were approximately threefold higher than that of the other patients at that time. On the other hand, the treatment success rate was 76.9% at 7 days after the second administration, which was comparable with the expected level. The present study not only demonstrates that HF meal intake increases the IVM concentration in plasma and the stratum corneum in Japanese patients with scabies, but also suggests the possibility that HF meals increase the risk of hepatic dysfunction by the increased exposure of IVM. © 2016 Japanese Dermatological Association. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19950048218&hterms=Viking&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D60%26Ntt%3DViking','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19950048218&hterms=Viking&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D60%26Ntt%3DViking">DE 1 and Viking observations associated with electron conical distributions</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Menietti, J. D.; Weimer, D. R.; Andre, M.; Eliasson, L. 1994-01-01 Data from the electron detectors on board the Swedish Viking satellite launched during a period of low solar activity and from the Dynamic Explorer (DE) 1 satellite launched during active solar coditions have been examined for the occurrence and location of electron conical distributions and several conclusions can be drawn. First, we note that most of the best examples of electron conics observed by the V-3 experiment onboard Viking occurred in the afternoon sector in the range of magneitc local time 14 hours less than Magnetic Local Time (MLT) less than 18 hours, at midaltitudes in the range 10,000 km less than h less than 13,500 km, with few occurring in the nightside auroral region, a region poorly sampled at altitudes greater than 5000 km. For the Viking data there is an association of electron conics with upper hybrid waves. DE 1 observations made by the high-altitude plasma instrument (HAPI) indicate that electron conics were observed in the midmorning sector and the late evening sector, and as has been reported earlier, the correlation with upper hybird waves was good. The HAPI did not sample the afternoon sector. The electon conics observed on both satellites occurred in the presence of at least a modest (several kilovolts) potential difference beneath the satellite with a maximum energy that was usually, but not always, equal to or greater than the maximum energy of the electron conics. Two independent sets of observations by DE 1 suggest two distinct production mechanisms for electron conics. Examiniation of DE 1 electric field measurements from the plasma wave instrument during the observation of electron conics show simultaneous parallel oscillations in the frequency range of 0.2 Hz less than f less than 0.5 Hz during one and perhaps two of four events examined, and upper hybrid waves were observed on all four events. In addition, recent observations of '90-deg' electron conics associated with auroral kilometric radiation source regions suggest a perpendicular heating mechanism produced by wave-particle interaction. Such distributions may be observed as electron conics at higher altitudes. These results suggest more than one possible source mechanism may be responsible for electron conics. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1990ApPhL..57.2543O','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1990ApPhL..57.2543O">Microwave plasma generation of arsine from hydrogen and solid arsenic</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Omstead, Thomas R.; Annapragada, Ananth V.; Jensen, Klavs F. 1990-12-01 The generation of arsine from the reactions of hydrogen and elemental arsenic in a microwave plasma reactor is described. The arsenic is evaporated from a solid source upstream and carried into the microwave plasma region by a mixture of hydrogen and argon. Stable reaction products, arsine and diarsine are observed by molecular beam sampled mass spectroscopy along with partially hydrogenated species (e.g., AsH and AsH2). The effect of composition and flow rate of the argon/hydrogen carrier gas mixture on the amount of arsine generated is investigated. The arsine production reaches a maximum for an argon-to-hydrogen ratio of unity indicating that metastable argon species act as energy transfer intermediates in the overall reaction. The generation of arsine and diarsine from easily handled solid arsenic by this technique makes it attractive as a possible arsenic source for the growth of compound semiconductors by low-pressure metalorganic chemical vapor deposition.<lz> <lz> <lz> <lz> <lz> </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018AIPA....8e5227M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018AIPA....8e5227M">Whistler waves with electron temperature anisotropy and non-Maxwellian distribution functions</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Malik, M. Usman; Masood, W.; Qureshi, M. N. S.; Mirza, Arshad M. 2018-05-01 The previous works on whistler waves with electron temperature anisotropy narrated the dependence on plasma parameters, however, they did not explore the reasons behind the observed differences. A comparative analysis of the whistler waves with different electron distributions has not been made to date. This paper attempts to address both these issues in detail by making a detailed comparison of the dispersion relations and growth rates of whistler waves with electron temperature anisotropy for Maxwellian, Cairns, kappa and generalized (r, q) distributions by varying the key plasma parameters for the problem under consideration. It has been found that the growth rate of whistler instability is maximum for flat-topped distribution whereas it is minimum for the Maxwellian distribution. This work not only summarizes and complements the previous work done on the whistler waves with electron temperature anisotropy but also provides a general framework to understand the linear propagation of whistler waves with electron temperature anisotropy that is applicable in all regions of space plasmas where the satellite missions have indicated their presence. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19930010003','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19930010003">The solar wind structure that caused a large-scale disturbance of the plasma tail of comet Austin</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Kozuka, Yukio; Konno, Ichishiro; Saito, Takao; Numazawa, Shigemi 1992-01-01 The plasma tail of Comet Austin (1989c1) showed remarkable disturbances because of the solar maximum periods and its orbit. Figure 1 shows photographs of Comet Austin taken in Shibata, Japan, on 29 Apr. 1990 UT, during about 20 minutes with the exposure times of 90 to 120 s. There are two main features in the disturbance; one is many bowed structures, which seem to move tailwards; and the other is a large-scale wavy structure. The bowed structures can be interpreted as arcade structures brushing the surface of both sides of the cometary plasma surrounding the nucleus. We identified thirteen structures of the arcades from each of the five photographs and calculated the relation between the distance of each structure from the cometary nucleus, chi, and the velocity, upsilon. The result is shown. This indicates that the velocity of the structures increases with distance. This is consistent with the result obtained from the observation at the Kiso Observatory. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22661139-photospheric-velocity-structures-during-emergence-small-active-regions-sun','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22661139-photospheric-velocity-structures-during-emergence-small-active-regions-sun"></a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Khlystova, Anna; Toriumi, Shin, E-mail: hlystova@iszf.irk.ru, E-mail: shin.toriumi@nao.ac.jp We study the plasma flows in the solar photosphere during the emergence of two small active regions, NOAA 9021 and 10768. Using Solar and Heliospheric Observatory /Michelson Doppler Imager data, we find that the strong plasma upflows appear at the initial stage of active region formation, with maximum upflow velocities of −1650 and −1320 m s{sup −1}. The structures with enhanced upflows have size ∼8 Mm in diameter, and they exist for 1–2 hr. The parameters of the enhanced upflows are consistent with those of the large active region NOAA 10488, which may suggest the possibility that the elementary emergingmore » magnetic loops that appear at the earliest phase of active region formation have similar properties, irrespective of scales of active regions. Comparison between the observations and a numerical simulation of magnetic flux emergence shows a striking consistency. We find that the driving force of the plasma upflow is at first the gas pressure gradient and later the magnetic pressure gradient.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1249057','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/1249057">9 GeV energy gain in a beam-driven plasma wakefield accelerator</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Litos, M.; Adli, E.; Allen, J. M. 2016-02-15 An electron beam has gained a maximum energy of 9 GeV per particle in a 1.3 m-long electron beam-driven plasma wakefield accelerator. The amount of charge accelerated in the spectral peak was 28.3 pC, and the root-mean-square energy spread was 5.0%. The mean accelerated charge and energy gain per particle of the 215 shot data set was 115 pC and 5.3 GeV, respectively, corresponding to an acceleration gradient of 4.0 GeV m -1 at the spectral peak. Moreover, the mean energy spread of the data set was 5.1%. Our results are consistent with the extrapolation of the previously reported energymore » gain results using a shorter, 36 cm-long plasma source to within 10%, evincing a non-evolving wake structure that can propagate distances of over a meter in length. Wake-loading effects were evident in the data through strong dependencies observed between various spectral properties and the amount of accelerated charge.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19850029408&hterms=environnement&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3Denvironnement','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19850029408&hterms=environnement&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3Denvironnement">Linear analysis of ion cyclotron interaction in a multicomponent plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Gendrin, R.; Ashour-Abdalla, M.; Omura, Y.; Quest, K. 1984-01-01 The mechanism by which hot anisotropic protons generate electromagnetic ion cyclotron waves in a plasma containing cold H(+) and He(+) ions is quantitatively studied. Linear growth rates (both temporal and spatial) are computed for different plasma parameters: concentration, temperature,and anisotropy of cold He(+) ions and of hot protons. It is shown that: (1) for parameters typical of the geostationary altitude the maximum growth rates are not drastically changed when a small proportion (about 1 to 20 percent) of cold He(+) ions is present; (2) because of the important cyclotron absorption by thermal He(+) ions in the vicinity of the He(+) gyrofrequency, waves which could resonate with the bulk of the He(+) distribution cannot be generated. Therefore quasi-linear effects, in a homogeneous medium at least, cannot be responsible for the heating of He(+) ions which is often observed in conjunction with ion cyclotron waves. The variation of growth rate versus wave number is also studied for its importance in selecting suitable parameters in numerical simulation experiments. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017RuMet2017..735B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017RuMet2017..735B">Distribution of deuterium and hydrogen in Zr and Ti foil assemblies under the action of a pulsed deuterium high-temperature plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Bondarenko, G. G.; Volobuev, I. V.; Eriskin, A. A.; Kobzev, A. P.; Nikulin, V. Ya.; Peregudova, E. N.; Silin, P. V.; Borovitskaya, I. V. 2017-09-01 Deuteron and proton elastic recoil detection analysis is used to study the accumulation and redistribution of deuterium and hydrogen in assemblies of two high-pure zirconium or titanium foils upon pulsed action of high-temperature deuterium plasma (PHTDP) in a plasma-focus installation PF-4. It is noted that, under the action of PHTDP, an implanted deuterium and hydrogen gas impurity are redistributed in the irradiated foils in large depths, which are significantly larger than the deuterium ion free paths (at their maximum velocity to 108 cm/s). The observed phenomenon is attributed to the carrying out of implanted deuterium and hydrogen under the action of powerful shock waves formed in the metallic foils under the action of PHTDP and/or the acceleration of diffusion of deuterium and hydrogen atoms under the action of a compression-rarefaction shock wave at the shock wave front with the redistribution of deuterium and hydrogen to large depths. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015PlPhR..41..281M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015PlPhR..41..281M">Optical characteristics and parameters of gas-discharge plasma in a mixture of mercury dibromide vapor with argon</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Malinina, A. A.; Malinin, A. N. 2015-03-01 Results are presented from studies of the optical characteristics and parameters of the plasma of a dielectric barrier discharge in a mixture of mercury dibromide vapor with argon—the working medium of an exciplex gas-discharge emitter. It is established that the partial pressures of mercury dibromide vapor and argon at which the average and pulsed emission intensities in the blue—green spectral region (λmax = 502 nm) reach their maximum values are 0.6 and 114.4 kPa, respectively. The electron energy distribution function, the transport characteristics, the specific power spent on the processes involving electrons, the electron density and temperature, and the rate constants for the processes of elastic and inelastic electron scattering from the molecules and atoms of the working mixture are determined by numerical simulation, and their dependences on the reduced electric field strength are analyzed. The rate constant of the process leading to the formation of exciplex mercury monobromide molecules for a reduced electric field of E/ N = 20 Td, at which the maximum emission intensity in the blue—green spectral region was observed in this experiment, is found to be 8.1 × 10-15 m3/s. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JPS...336...99C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JPS...336...99C">Feasibility study of surface-modified carbon cloth electrodes using atmospheric pressure plasma jets for microbial fuel cells</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Chang, Shih-Hang; Liou, Jyun-Sian; Liu, Jung-Liang; Chiu, Yi-Fan; Xu, Chang-Han; Chen, Bor-Yann; Chen, Jian-Zhang 2016-12-01 This study investigated the surface and electrochemical properties of carbon cloth electrodes surface-modified by using atmospheric pressure plasma jets (APPJs) for applications involving microbial fuel cells (MFCs). APPJ treatment made the carbon cloth highly hydrophilic and did not introduce any observable cracks or flaws. MFCs configured with APPJ-treated carbon cloth electrodes exhibited electrochemical performance (maximum power density of 7.56 mW m-2) superior to that of MFCs configured with untreated carbon cloth electrodes (maximum power density of 2.38 mW m-2). This boost in performance can be attributed to the formation of abundant carboxyl and ammonium functional groups on the surface of APPJ-treated carbon cloth, which promoted the formation of anodic biofilms and the adhesion of bacteria, while facilitating the transfer of electrons from the bacteria to the electrodes. APPJ surface modification is non-toxic and environmentally friendly (no exogenous chemicals are required), which is particularly beneficial as the introduction of toxins might otherwise inhibit bacterial growth and metabolism. The APPJ surface modification process is rapid, cost-effective, and applicable to substrates covering a large area, making it ideal for the fabrication of large-scale MFCs and bioelectrochemical bioenergy devices. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22452491','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22452491">Comparison of glomerular filtration rate determined by use of single-slice dynamic computed tomography and scintigraphy in cats.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Schmidt, David M; Scrivani, Peter V; Dykes, Nathan L; Goldstein, Richard M; Erb, Hollis N; Reeves, Anthony P 2012-04-01 To compare estimation of glomerular filtration rate determined via conventional methods (ie, scintigraphy and plasma clearance of technetium Tc 99m pentetate) and dynamic single-slice computed tomography (CT). 8 healthy adult cats. Scintigraphy, plasma clearance testing, and dynamic CT were performed on each cat on the same day; order of examinations was randomized. Separate observers performed GFR calculations for scintigraphy, plasma clearance testing, or dynamic CT. Methods were compared via Bland-Altman plots and considered interchangeable and acceptable when the 95% limits of agreement (mean difference between methods ± 1.96 SD of the differences) were ≤ 0.7 mL/min/kg. Global GFR differed < 0.7 mL/min/kg in 5 of 8 cats when comparing plasma clearance testing and dynamic CT; the limits of agreement were 1.4 and -1.7 mL/min/kg. The mean ± SD difference was -0.2 ± 0.8 mL/min/kg, and the maximum difference was 1.6 mL/min/kg. The mean ± SD difference (absolute value) for percentage filtration by individual kidneys was 2.4 ± 10.5% when comparing scintigraphy and dynamic CT; the maximum difference was 20%, and the limits of agreement were 18% and 23% (absolute value). GFR estimation via dynamic CT exceeded the definition for acceptable clinical use, compared with results for conventional methods, which was likely attributable to sample size and preventable technical complications. Because 5 of 8 cats had comparable values between methods, further investigation of dynamic CT in a larger sample population with a wide range of GFR values should be performed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/20120008262','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20120008262">Understanding the Impact of Return-Current Losses on the X-Ray Emission from Solar Flares</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Holman, Gordon D. 2012-01-01 I obtain and examine the implications of one-dimensional analytic solutions for return-current losses on an initially power-law distribution of energetic electrons with a sharp low-energy cutoff in flare plasma with classical (collisional) resistivity. These solutions show, for example, that return-current losses are not sensitive to plasma density, but are sensitive to plasma temperature and the low energy cutoff of the injected nonthermal electron distribution. A characteristic distance from the electron injection site, x(sub rc), is derived. At distances less than x(sub rc) the electron flux density is not reduced by return-current losses, but plasma heating can be substantial in this region, in the upper, coronal part of the flare loop. Before the electrons reach the collisional thick-target region of the flare loop, an injected power-law electron distribution with a low-energy cutoff maintains that structure, but with a flat energy distribution below the cutoff energy, which is now determined by the total potential drop experienced by the electrons. Modifications due to the presence of collisional losses are discussed. I compare these results with earlier analytical results and with more recent numerical simulations. Emslie's 1980 conjecture that there is a maximum integrated X-ray source brightness on the order of 10(exp -15) photons per square centimeter per second per square centimeter is examined. I find that this is not actually a maximum brightness and its value is parameter dependent, but it is nevertheless a valuable benchmark for identifying return-current losses in hard X-ray spectra. I discuss an observational approach to identifying return-current losses in flare data, including identification of a return-current "bump" in X-ray light curves at low photon energies. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25747988','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25747988">Pharmacokinetics and brain distribution of tetrahydropalmatine and tetrahydroberberine after oral administration of DA-9701, a new botanical gastroprokinetic agent, in rats.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Jung, Ji Won; Kwon, Yong Sam; Jeong, Jin Seok; Son, Miwon; Kang, Hee Eun 2015-01-01 DA-9701, a new botanical gastroprokinetic agent, has potential for the management of delayed gastric emptying in Parkinson's disease if it has no central anti-dopaminergic activity. Therefore, we examined the pharmacokinetics of DA-9701 components having dopamine D2 receptor antagonizing activity, tetrahydropalmatine (THP) and tetrahydroberberine (THB), following various oral doses (80-328 mg/kg) of DA-9701. The distribution of THP and THB to the brain and/or other tissues was also evaluated after single or multiple oral administrations of DA-9701. Oral administration of DA-9701 yielded dose-proportional area under the plasma concentration-time curve (AUC0-8 h) and maximum plasma concentration (Cmax) values for THP and THB, indicating linear pharmacokinetics (except for THB at the lowest dose). THP and THB's large tissue-to-plasma concentration ratios indicated considerable tissue distribution. High concentrations of THP and THB in the stomach and small intestine suggest an explanation for DA-9701's potent gastroprokinetic activity. The maximum concentrations of THP and THB in brain following multiple oral DA-9701 for 7 d (150 mg/kg/d) was observed at 30 min after the last oral DA-9701 treatment: 131±67.7 ng/g for THP and 6.97±4.03 ng/g for THB. Although both THP and THB pass through the blood-brain barrier, as indicated by brain-to-plasma concentration ratios greater than unity (approximately 2-4), oral administration of DA-9701 at the effective dose in humans is not expected to lead to sufficient brain concentrations to exert central dopamine D2 receptor antagonism. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18177321','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18177321">Pharmacokinetics of tilmicosin in equine tissues and plasma.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Clark, C; Dowling, P M; Ross, S; Woodbury, M; Boison, J O 2008-02-01 The macrolide antibiotic tilmicosin has potential for treating bacterial respiratory tract infections in horses. A pharmacokinetic study evaluated the disposition of tilmicosin in the horse after oral (4 mg/kg) or subcutaneous (s.c.) (10 mg/kg) administration. Tilmicosin was not detected in equine plasma or tissues after oral administration at this dose. With s.c. injection, tilmicosin concentrations reached a maximum concentration of approximately 200 ng/mL in the plasma of the horses. Tilmicosin concentrations in plasma persisted with a mean residence time (MRT) of 19 h. Maximum tissue residue concentrations (C(max)) of tilmicosin measured in equine lung, kidney, liver and muscle tissues after s.c. administration were 2784, 4877, 1398, and 881 ng/g, respectively. The MRT of tilmicosin in these tissues was approximately 27 h. Subcutaneous administration of tilmicosin resulted in severe reactions at the injection sites. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18309608','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18309608">Effect of inhomogeneity of light from light curing units on the surface hardness of composite resin.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Arikawa, Hiroyuki; Kanie, Takahito; Fujii, Koichi; Takahashi, Hideo; Ban, Seiji 2008-01-01 This study investigated the characteristics of output light from different types of light curing units, and their effects on polymerization of light-activated composite resin. Three quartz-tungsten-halogen lamps, one plasma arc lamp, and one LED light curing unit were used. Intensity distribution of light emitted from the light guide tip was measured at 1.0-mm intervals across the guide tip. Distribution of Knoop hardness number on the surface of resin irradiated with the light curing units was also measured. For all units, inhomogeneous distribution of light intensity across the guide tip was observed. Minimum light intensity values were 19-80% of the maximum values. In terms of surface hardness, inhomogeneous distribution was also observed for the materials irradiated with the tested units. Minimum values were 53-92% of the maximum values. Our results indicated that markedly inhomogeneous light emitted from light curing unit could result in inhomogeneous polymerization in some areas of the restoration below the light guide tip. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li class="active">13</li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_14" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li class="active">14</li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="261"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5171222','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5171222">Towards graphane field emitters</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Ding, Shuyi; Li, Chi; Zhou, Yanhuai; Collins, Clare M.; Kang, Moon H.; Parmee, Richard J.; Zhang, Xiaobing; Milne, William I.; Wang, Baoping 2015-01-01 We report on the improved field emission performance of graphene foam (GF) following transient exposure to hydrogen plasma. The enhanced field emission mechanism associated with hydrogenation has been investigated using Fourier transform infrared spectroscopy, plasma spectrophotometry, Raman spectroscopy, and scanning electron microscopy. The observed enhanced electron emissionhas been attributed to an increase in the areal density of lattice defects and the formation of a partially hydrogenated, graphane-like material. The treated GF emitter demonstrated a much reduced macroscopic turn-on field (2.5 V μm–1), with an increased maximum current density from 0.21 mA cm–2 (pristine) to 8.27 mA cm–2 (treated). The treated GFs vertically orientated protrusions, after plasma etching, effectively increased the local electric field resulting in a 2.2-fold reduction in the turn-on electric field. The observed enhancement is further attributed to hydrogenation and the subsequent formation of a partially hydrogenated structured 2D material, which advantageously shifts the emitter work function. Alongside augmentation of the nominal crystallite size of the graphitic superstructure, surface bound species are believed to play a key role in the enhanced emission. The hydrogen plasma treatment was also noted to increase the emission spatial uniformity, with an approximate four times reduction in the per unit area variation in emission current density. Our findings suggest that plasma treatments, and particularly hydrogen and hydrogen-containing precursors, may provide an efficient, simple, and low cost means of realizing enhanced nanocarbon-based field emission devices via the engineered degradation of the nascent lattice, and adjustment of the surface work function. PMID:28066543 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27876610','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27876610">Establishing reference intervals for hCG in postmenopausal women.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Patel, Khushbu K; Qavi, Abraham J; Hock, Karl G; Gronowski, Ann M 2017-03-01 Plasma concentrations of human chorionic gonadotropin (hCG) have been shown to increase with age due to pituitary secretion. We previously recommended that an hCG cutoff of 14.0IU/L be used for women ≥55years of age. However, it remains unknown whether concentrations >14.0IU/L can be expected in women with advanced age. Our objectives were to establish plasma hCG reference intervals and correlate follicle stimulating hormone (FSH) and hCG concentrations in postmenopausal females ≥55years. Residual plasma samples from 798 women ≥55years were utilized with 303, 269, and 226 samples belonging to the age groups 55-69, 70-84, and ≥85years, respectively. FSH and hCG were measured using the Abbott ARCHITECT. All positive hCG samples (hCG ≥5IU/L) were analyzed for potential heterophile antibody interference and 3 were excluded. Electronic medical records were reviewed and patients with malignancy were excluded. 8% (56/666) of women age≥55years had plasma hCG ≥5IU/L. There were 19, 16, and 21 patients with hCG ≥5IU/L in the age groups 55-69, 70-84, and ≥85years, respectively. The highest hCG concentrations observed in each age group were: 55-69years maximum=11.7IU/L and 97.5th percentile=9.6IU/L; 70-84years maximum=18.09IU/L, 97.5th percentile=6.2IU/L; ≥85years maximum=11.1IU/L and 97.5th percentile=10.0IU/L, and the overall 97.5th percentile=8.5IU/L for all women ≥55years of age. Neither hCG nor FSH concentrations continued to increase with age in women ≥55years. The prevalence of positive hCG in women ≥55years is 8%. This study confirms our previously recommended cutoff of 14IU/L for women ≥55years of age. In women ≥55years of age, FSH concentrations do not predict hCG concentrations. Copyright © 2016 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JPlPh..83c9005S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JPlPh..83c9005S">Large-amplitude acoustic solitary waves in a Yukawa chain</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Sheridan, T. E.; Gallagher, James C. 2017-06-01 We experimentally study the excitation and propagation of acoustic solitary waves in a one-dimensional dusty plasma (i.e. a Yukawa chain) with particles interacting through a screened Coulomb potential. The lattice constant mm. Waves are launched by applying a 100 mW laser pulse to one end of the chain for laser pulse durations from 0.10 to 2.0 s. We observe damped solitary waves which propagate for distances with an acoustic speed s=11.5\\pm 0.2~\\text{mm}~\\text{s}-1$ . The maximum velocity perturbation increases with laser pulse duration for durations s and then saturates at . The wave speed is found to be independent of the maximum amplitude, indicating that the formation of nonlinear solitons is prevented by neutral-gas damping. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15084019','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15084019">Effects of mating behaviour and the ovarian follicular state of female alpacas on conception.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Vaughan, J L; Macmillan, K L; Anderson, G A; D'Occhio, M J 2003-01-01 To determine relationships between mating behaviour, ovarian follicular state and successful conception in receptive female alpacas. Seventy pen matings were observed at a commercial alpaca stud in south-western Victoria. The behaviours observed included time taken to assume sternal recumbency, mating duration, and evidence of nonreceptive behaviour such as spitting, kicking and vocalisation. Ovarian follicular state was determined by ultrasonography, which was complemented by measuring plasma concentrations of oestradiol and progesterone. Pregnancies were confirmed by transabdominal ultrasonography between days 45 and 80 after mating. There were no significant differences between receptive females that conceived and those that failed to conceive in the time taken to adopt the copulation position of sternal recumbency, mating duration, or maximum follicle diameter. There was no significant relationship between time taken to assume sternal recumbency (log10) and maximum follicle diameter or plasma oestradiol (log10). However, there was a significant quadratic relationship between plasma oestradiol concentration (log10) and follicle diameter, and the probability of pregnancy increased as the plasma concentration of oestradiol (log10) at the time of mating increased. Females were sexually receptive most of the time in the absence of a corpus luteum, and regardless of size of the largest follicle or plasma concentration of oestradiol. Breed (Huacaya vs Suri), site of the dominant follicle (left or right ovary), lactation state, number of matings by the male (1 or 2), or interval between parturition and mating, did not affect pregnancy outcome. Follicles with a diameter less than 7 mm were able to ovulate in response to mating. This was smaller than previously reported. Thirty-four pregnancies (49% pregnancy rate) resulted in 30 (88%) births with a gestation length of 343 days (SEM +/- 2, range 316-367 days). There were 4 (12%) abortions between days 45 and 80 of gestation and full term. It was not possible to correlate mating behaviour and ovarian state with conception. To optimise pregnancy rates in receptive alpacas, matings need to occur in the presence of an oestrogenic follicle that is capable of ovulation in response to mating. A simple method of detecting alpacas with follicles in this state is not currently available and treatments that control ovarian follicular growth should therefore be investigated. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/21072663-filamentation-instability-quantum-plasma','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/21072663-filamentation-instability-quantum-plasma">Filamentation instability in a quantum plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Bret, A. 2007-08-15 The growth rate of the filamentation instability triggered when a diluted cold electron beam passes through a cold plasma is evaluated using the quantum hydrodynamic equations. Compared with a cold fluid model, quantum effects reduce both the unstable wave vector domain and the maximum growth rate. Stabilization of large wave vector modes is always achieved, but significant reduction of the maximum growth rate depends on a dimensionless parameter that is provided. Although calculations are extended to the relativistic regime, they are mostly relevant to the nonrelativistic one. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22156306-source-sup-dt-neutron-yield-basis-spherical-plasma-focus-chamber','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22156306-source-sup-dt-neutron-yield-basis-spherical-plasma-focus-chamber">A source with a 10{sup 13} DT neutron yield on the basis of a spherical plasma focus chamber</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Zavyalov, N. V.; Maslov, V. V.; Rumyantsev, V. G., E-mail: rumyantsev@expd.vniief.ru 2013-03-15 Results from preliminary experimental research of neutron emission generated by a spherical plasma focus chamber filled with an equal-component deuterium-tritium mixture are presented. At a maximum current amplitude in the discharge chamber of {approx}1.5 MA, neutron pulses with a full width at half-maximum of 75-80 ns and an integral yield of {approx}1.3 Multiplication-Sign 10{sup 13} DT neutrons have been recorded. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA165430','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA165430">A Plasma Ultraviolet Source for Short Wavelength Lasers.</a> <a target="_blank" rel="noopener noreferrer" href="http://www.dtic.mil/">DTIC Science & Technology</a> 1986-03-10 A high power blue-green laser was pumped with an array of the dense plasma focus . As the result of optimizing the operating conditions of the dense... plasma focus and laser system, the maximum untuned laser output exceeded 2.lmJ corresponding to the energy density 3J/cu cm which is much higher than </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017MNRAS.468.3709S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017MNRAS.468.3709S">Interstellar scintillations of PSR B1919+21: space-ground interferometry</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Shishov, V. I.; Smirnova, T. V.; Gwinn, C. R.; Andrianov, A. S.; Popov, M. V.; Rudnitskiy, A. G.; Soglasnov, V. A. 2017-07-01 We carried out observations of pulsar PSR B1919+21 at 324 MHz to study the distribution of interstellar plasma in the direction of this pulsar. We used the RadioAstron (RA) space radio telescope, together with two ground telescopes: Westerbork (WB) and Green Bank (GB). The maximum baseline projection for the space-ground interferometer was about 60 000 km. We show that interstellar scintillation of this pulsar consists of two components: diffractive scintillations from inhomogeneities in a layer of turbulent plasma at a distance z1 = 440 pc from the observer or homogeneously distributed scattering material to the pulsar; and weak scintillations from a screen located near the observer at z2 = 0.14 ± 0.05 pc. Furthermore, in the direction to the pulsar we detected a prism that deflects radiation, leading to a shift in observed source position. We show that the influence of the ionosphere can be ignored for the space-ground baseline. Analysis of the spatial coherence function for the space-ground baseline (RA-GB) yielded a scattering angle in the observer plane of θscat = 0.7 mas. An analysis of the time-frequency correlation function for weak scintillations yielded an angle of refraction in the direction to the pulsar θref, 0 = 110 ms and a distance to the prism zprism ≤ 2 pc. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3844101','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3844101">In Vivo Absorption and Disposition of Cefadroxil after Escalating Oral Doses in Wild-Type and PepT1 Knockout Mice</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Posada, Maria M.; Smith, David E. 2013-01-01 Purpose To determine the effect of PepT1 on the absorption and disposition of cefadroxil, including the potential for saturable intestinal uptake, after escalating oral doses of drug. Methods The absorption and disposition kinetics of [3H]cefadroxil was determined in wild-type and PepT1 knockout mice after 44.5, 89.1, 178, and 356 nmol/g oral doses of drug. The pharmacokinetics of [3H]cefadroxil was also determined in both genotypes after 44.5 nmol/g intravenous bolus doses. Results PepT1 deletion reduced the area under the plasma concentration-time profile (AUC0-120) of cefadroxil by 10-fold, the maximum plasma concentration (Cmax) by 17.5-fold, and increased the time to reach a maximum plasma concentration (Tmax) by 3-fold. There was no evidence of nonlinear intestinal absorption since AUC0-120 and Cmax values changed in a dose-proportional manner. Moreover, the pharmacokinetics of cefadroxil was not different between genotypes after intravenous bolus doses, indicating that PepT1 did not affect drug disposition. Finally, no differences were observed in the peripheral tissue distribution of cefadroxil (i.e., outside gastrointestinal tract) once these tissues were corrected for differences in perfusing blood concentrations. Conclusions The findings demonstrate convincingly the critical role of intestinal PepT1 in both the rate and extent of oral administration for cefadroxil and potentially other aminocephalosporin drugs. PMID:23959853 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22716224','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22716224">The absorption profile of pregabalin in chronic pancreatitis.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Olesen, Anne E; Olofsen, Erik; Olesen, Søren S; Staahl, Camilla; Andresen, Trine; Dahan, Albert; Drewes, Asbjørn M 2012-12-01 It was recently shown that pregabalin decreased pain associated with chronic pancreatitis. It is well known that pancreatitis patients suffer from fat malabsorption with accompanying diarrhoea because of loss of exocrine pancreatic enzyme production. This may lead to changes in the mucosal surface in the small intestine and possibly affect the absorption of pregabalin. The pharmacokinetics of pregabalin has never been investigated in patients suffering from chronic pancreatitis. The aim of this study was to develop a population pharmacokinetic model of pregabalin administered to patients with chronic pancreatitis. The pregabalin population pharmacokinetic analysis was conducted on data from fifteen patients with chronic pancreatitis. Each patient received 75 mg of pregabalin (oral capsule). Pregabalin concentrations were measured using a validated liquid chromatographic method. Data analysis was performed using non-linear mixed effects modelling methodology as implemented by NONMEM. A one-compartment model with first-order absorption and elimination adequately described pregabalin pharmacokinetics. Time to maximum observed plasma concentration (T(max) ) was 1.53 (95% CI 1.09-2.05). The maximum plasma concentration (C(max) ) was 1.98 μg/ml (95% CI 1.69-2.34), and area under the plasma concentration-time profile (area under the curve) was 18.2 μg*hr/ml (95% CI 14.7-26.3). Pregabalin is well absorbed in patients with chronic pancreatitis, and the pharmacokinetic profile of pregabalin is not extensively affected by chronic pancreatitis. © 2012 The Authors Basic & Clinical Pharmacology & Toxicology © 2012 Nordic Pharmacological Society. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017PlPhR..43..733P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017PlPhR..43..733P">On fast solid-body rotation of the solar core and differential (liquid-like) rotation of the solar surface</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Pashitskii, E. A. 2017-07-01 On the basis of a two-component (two-fluid) hydrodynamic model, it is shown that the probable phenomenon of solar core rotation with a velocity higher than the average velocity of global rotation of the Sun, discovered by the SOHO mission, can be related to fast solid-body rotation of the light hydrogen component of the solar plasma, which is caused by thermonuclear fusion of hydrogen into helium inside the hot dense solar core. Thermonuclear fusion of four protons into a helium nucleus (α-particle) creates a large free specific volume per unit particle due to the large difference between the densities of the solar plasma and nuclear matter. As a result, an efficient volumetric sink of one of the components of the solar substance—hydrogen—forms inside the solar core. Therefore, a steady-state radial proton flux converging to the center should exist inside the Sun, which maintains a constant concentration of hydrogen as it burns out in the solar core. It is demonstrated that such a converging flux of hydrogen plasma with the radial velocity v r ( r) = -β r creates a convective, v r ∂ v φ/∂ r, and a local Coriolis, v r v φ/ r,φ nonlinear hydrodynamic forces in the solar plasma, rotating with the azimuthal velocity v φ. In the absence of dissipation, these forces should cause an exponential growth of the solid-body rotation velocity of the hydrogen component inside the solar core. However, friction between the hydrogen and helium components of the solar plasma due to Coulomb collisions of protons with α-particles results in a steady-state regime of rotation of the hydrogen component in the solar core with an angular velocity substantially exceeding the global rotational velocity of the Sun. It is suggested that the observed differential (liquid-like) rotation of the visible surface of the Sun (photosphere) with the maximum angular velocity at the equator is caused by sold-body rotation of the solar plasma in the radiation zone and strong turbulence in the tachocline layer, where the turbulent viscosity reaches its maximum value at the equator. There, the tachocline layer exerts the most efficient drag on the less dense outer layers of the solar plasma, which are slowed down due to the interaction with the ambient space plasma (solar wind). </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1326057-particle-cell-study-ion-electron-sheath-transition','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1326057-particle-cell-study-ion-electron-sheath-transition">Particle-in-cell study of the ion-to-electron sheath transition</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a> Scheiner, Brett; Baalrud, Scott D.; Hopkins, Matthew M.; ... 2016-08-09 The form of a sheath near a small electrode, with bias changing from below to above the plasma potential, is studied using 2D particle-in-cell simulations. When the electrode is biased within T e/2 e below the plasma potential, the electron velocity distribution functions (EVDFs) exhibit a loss-cone type truncation due to fast electrons overcoming the small potential difference between the electrode and plasma. No sheath is present in this regime, and the plasma remains quasineutral up to the electrode. The EVDF truncation leads to a presheath-like density and flow velocity gradients. Once the bias exceeds the plasma potential, an electronmore » sheath is present. In this case, the truncation driven behavior persists, but is accompanied by a shift in the maximum value of the EVDF that is not present in the negative bias cases. In conclusion, the flow moment has significant contributions from both the flow shift of the EVDF maximum, and the loss-cone truncation.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018MNRAS.474.4837B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018MNRAS.474.4837B">Linear feature detection algorithm for astronomical surveys - II. Defocusing effects on meteor tracks</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Bektešević, Dino; Vinković, Dejan; Rasmussen, Andrew; Ivezić, Željko 2018-03-01 Given the current limited knowledge of meteor plasma micro-physics and its interaction with the surrounding atmosphere and ionosphere, meteors are a highly interesting observational target for high-resolution wide-field astronomical surveys. Such surveys are capable of resolving the physical size of meteor plasma heads, but they produce large volumes of images that need to be automatically inspected for possible existence of long linear features produced by meteors. Here, we show how big aperture sky survey telescopes detect meteors as defocused tracks with a central brightness depression. We derive an analytic expression for a defocused point source meteor track and use it to calculate brightness profiles of meteors modelled as uniform brightness discs. We apply our modelling to meteor images as seen by the Sloan Digital Sky Survey and Large Synoptic Survey Telescope telescopes. The expression is validated by Monte Carlo ray-tracing simulations of photons travelling through the atmosphere and the Large Synoptic Survey Telescope telescope optics. We show that estimates of the meteor distance and size can be extracted from the measured full width at half-maximum and the strength of the central dip in the observed brightness profile. However, this extraction becomes difficult when the defocused meteor track is distorted by the atmospheric seeing or contaminated by a long-lasting glowing meteor trail. The full width at half-maximum of satellite tracks is distinctly narrower than meteor values, which enables removal of a possible confusion between satellites and meteors. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013APS..DPPCP8091C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013APS..DPPCP8091C">Probing RFP Density Limits and the Interaction of Pellet Fueling and NBI Heating on MST</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Caspary, K. J.; Chapman, B. E.; Anderson, J. K.; Limbach, S. T.; Oliva, S. P.; Sarff, J. S.; Waksman, J.; Combs, S. K.; Foust, C. R. 2013-10-01 Pellet fueling on MST has previously achieved Greenwald fractions of up to 1.5 in 200 kA improved confinement discharges. Additionally, pellet fueling to densities above the Greenwald limit in 200 kA standard discharges resulted in early termination of the plasma, but pellet size was insufficient to exceed the limit for higher current discharges. To this end, the pellet injector on MST has been upgraded to increase the maximum fueling capability by increasing the size of the pellet guide tubes, which constrain the lateral motion of the pellet in flight, to accommodate pellets of up to 4.0 mm in diameter. These 4.0 mm pellets are capable of triggering density limit terminations for MST's peak current of 600 kA. An unexpected improvement in the pellet speed and mass control was also observed compared to the smaller diameter pellets. Exploring the effect of increased density on NBI particle and heat deposition shows that for MST's 1 MW tangential NBI, core deposition of 25 keV neutrals is optimized for densities of 2-3 × 1019 m-3. This is key for beta limit studies in pellet fueled discharges with improved confinement where maximum NBI heating is desired. An observed toroidal deflection of pellets injected into NBI heated discharges is consistent with asymmetric ablation due to the fast ion population. In 200 kA improved confinement plasmas with NBI heating, pellet fueling has achieved a Greenwald fraction of 2.0. Work supported by US DoE. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22661378-pressure-pulses-voyager-drivers-interstellar-transients','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22661378-pressure-pulses-voyager-drivers-interstellar-transients">PRESSURE PULSES AT VOYAGER 2 : DRIVERS OF INTERSTELLAR TRANSIENTS?</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Richardson, J. D.; Wang, C.; Liu, Y. D. Voyager 1 ( V1 ) crossed the heliopause into the local interstellar medium (LISM) in 2012. The LISM is a dynamic region periodically disturbed by solar transients with outward-propagating shocks, cosmic-ray intensity changes and anisotropies, and plasma wave oscillations. Voyager 2 ( V2 ) trails V1 and thus may observe the solar transients that are later observed at V1. V2 crossed the termination shock in 2007 and is now in the heliosheath. Starting in 2012, when solar maximum conditions reached V2 , five possible merged interaction regions (MIRs) have been observed by V2 in the heliosheath. The timing is consistentmore » with these MIRs driving the transients observed by V1 in the LISM. The largest heliosheath MIR was observed by V2 in late 2015 and should reach V1 in 2018.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20080032403&hterms=correlated+anti-correlated&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3Dcorrelated%2Banti-correlated','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20080032403&hterms=correlated+anti-correlated&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3Dcorrelated%2Banti-correlated">Cassini UVIS Observations of the Io Plasma Torus. 3; Observations of Temporal and Azimuthal Variability</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Steffl, A. J.; Delamere, P. A.; Bagenal, F. 2006-01-01 In this third paper in a series presenting observations by the Cassini Ultraviolet Imaging Spectrometer (UVIS) of the Io plasma torus, we show remarkable, though subtle, spatio-temporal variations in torus properties. The Io torus is found to exhibit significant, near sinusoidal variations in ion composition as a functions of azimuthal position. The azimuthal variation in composition is such that the mixing ratio of S II us strongly correlated with the mixing ratio of S III and the equatorial electron density and strongly anti-correlated with the mixing ratios of both S IV and O II and the equatorial electron temperature. Surprisingly, the azimuthal variation in ion composition is observed to have a period of 10.07 h -- 1.5% longer than the System III rotation period of Jupiter, yet 1.3% shorter than the System UV period defined by [Brown, M. E., 1995. J. Geophys. Res. 100, 21683-21696]. Although the amplitude of the azimuthal variation of S III and O II remained in the range of 2-5%, the amplitude of the S II and S IV compositional variation ranged between 5 and 25% during the UVIS observations. Furthermore, the amplitude of the azimuthal variations of S II and S IV appears to be modulated by its location in System III longitude, such that when the region of maximum S II mixing ration (minimum S IV mixing ratio) is aligned with a System III longitude of 200 deg +/-, the amplitude is a factor of 4 greater than when the variation is anti-aligned. This behavior can explain numerous, often apparently contradictory, observations of variations in the properties of the Io plasma torus with the System III and System IV coordinate systems. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18067620','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18067620">Estimated plasma bupivacaine concentration after single dose and eight-hour continuous intra-articular infusion of bupivacaine in normal dogs.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Bubenik, Loretta; Hosgood, Giselle; Barker, Steven; Hicks, Merrin; Serra, Verna; Stout, Rhett 2007-12-01 To estimate maximum plasma concentration (C(max)) and time to maximum plasma (t(max)) bupivacaine concentration after intra-articular administration of bupivacaine for single injection (SI) and injection followed by continuous infusion (CI) in normal dogs. Cross-over design with a 2-week washout period. Healthy Coon Hound dogs (n=8). Using gas chromatography/mass spectrometry, canine plasma bupivacaine concentration was measured before and after SI (1.5 mg/kg) and CI (1.5 mg/kg and 0.3 mg/kg/h). Software was used to establish plasma concentration-time curves and estimate C(max), T(max) and other pharmacokinetic variables for comparison of SI and CI. Bupivacaine plasma concentration after SI and CI best fit a 3 exponential model. For SI, mean maximum concentration (C(max), 1.33+/-0.954 microg/mL) occurred at 11.37+/-4.546 minutes. For CI, mean C(max) (1.13+/-0.509 microg/mL) occurred at 10.37+/-4.109 minutes. The area under the concentration-time curve was smaller for SI (143.59+/-118.390 microg/mL x min) than for CI (626.502+/-423.653 microg/mL x min, P=.02) and half-life was shorter for SI (61.33+/-77.706 minutes) than for CI (245.363+/-104.415 minutes, P=.01). The highest plasma bupivacaine concentration for any dog was 3.2 microg/mL for SI and 2.3 microg/mL for CI. Intra-articular bupivacaine administration results in delayed absorption from the stifle into the systemic circulation with mean C(max) below that considered toxic and no systemic drug accumulation. Intra-articular bupivacaine can be administered with small risk of reaching toxic plasma concentrations in dogs, though toxic concentrations may be approached. Caution should be exercised with multimodal bupivacaine administration because plasma drug concentration may rise higher than with single intra-articular injection. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AAS...22534417H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AAS...22534417H">Extremely Hard X-ray Emission from Eta Carinae observed with XMM-Newton and NuSTAR around Periastron in 2014.5</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Hamaguchi, Kenji; Corcoran, Michael F.; Takahashi, Hiromitsu; Yuasa, Tadayuki; Groh, Jose H.; Russell, Christopher Michael Post; Pittard, Julian M.; Madura, Thomas; Owocki, Stanley P.; Grefenstette, Brian 2015-01-01 The super massive colliding wind binary system, Eta Carinae, experienced another periastron passage in the summer of 2014. We monitored this event using the multiple X-ray observatories, Chandra, XMM-Newton, NuSTAR, Suzaku and Swift. With a high eccentricity of its 5.5 year orbit, X-ray emission from the wind-wind collision (WWC) increases strongly toward periastron but then drops sharply by more than two orders of magnitude in two weeks around periastron due probably to an eclipse and an intrinsic activity decline of the WWC plasma. In this observing campaign, XMM-Newton and NuSTAR coordinated two simultaneous observations around the X-ray flux maximum on June 6 and just before the flux minimum on July 28. These two observations captured Eta Carinae with X-ray focusing telescopes in the extreme hard X-ray band above 10 keV for the first time.During the first observation, XMM and NuSTAR detected stable X-ray emission from the central binary system between 1 - 40 keV. A fit of a 1-temperature bremsstrahlung model to the high energy slope in the NuSTAR spectrum derives an electron temperature of ~6 keV, which is significantly higher than an ionization temperature at ~4.5 keV, measured from the Fe K emission lines resolved in the XMM spectrum.This result suggests the presence of very hot plasma and/or X-ray reflection at surrounding cold material. During the second observation, the X-ray flux between 5 - 10 keV declined steadily by a factor of ~2 in a day, while the other energy bands were rather stable. This variation may be explained by an increase of the line of sight absorption to emission from the plasma component that dominates above 5 keV. NuSTAR did not detect, in either observation, the very hard non-thermal component that dominated emission above 25 keV seen in earlier INTEGRAL and Suzaku observations. We discuss the plasma condition and the wind structure of Eta Carinae around periastron, and the nature of the non-thermal component. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JMiMi..28b5008K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JMiMi..28b5008K">Plasma extraction rate enhancement scheme for a real-time and continuous blood plasma separation device using a sheathless cell concentrator</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kang, Dong-Hyun; Kim, Kyongtae; Kim, Yong-Jun 2018-02-01 Microfluidic devices for plasma extraction are popular because they offer the advantage of smaller reagent consumption compared to conventional centrifugations. The plasma yield (volume percentage of plasma that can be extracted) is an important factor for diagnoses in microdevices with small reagent consumptions. However, recently designed microfluidic devices tend to have a low plasma yield because they have been optimized to improve the purity of extracted plasma. Thus, these devices require large amounts of reagents, and this complexity has eliminated the advantage of microfluidic devices that can operate with only small amounts of reagents. We therefore propose a continuous, real-time, blood plasma separation device, for plasma extraction rate enhancements. Moreover, a blood plasma separation device was designed to achieve improved plasma yields with high-purity efficiency. To obtain a high plasma yield, microstructures were placed on the bottom side of the channel to increase the concentration of blood cells. Plasma separation was then accomplished via microfluidic networks based on the Zweifach-Fung effect. The proposed device was fabricated based on the polydimethylsiloxane molding process using the SU-8 microfluidic channel for the fabrication of the mold and bottom structures. Human blood diluted in a phosphate buffered saline solution (25% hematocrit) was injected into the inlet of the device. The purity efficiencies were approximately equal to 96% with a maximum of 96.75% at a flow rate of 2 µl min-1, while the plasma yield was approximately 59% with a maximum of 59.92% at a flow rate of 4 µl min-1. Compared to results obtained using other devices, our proposed device could obtain comparable or higher plasma purity and a high plasma yield. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015APS..GECKW2003C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015APS..GECKW2003C">Negative hydrogen ions in a linear helicon plasma device</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Corr, Cormac; Santoso, Jesse; Samuell, Cameron; Willett, Hannah; Manoharan, Rounak; O'Byrne, Sean 2015-09-01 Low-pressure negative ion sources are of crucial importance to the development of high-energy (>1 MeV) neutral beam injection systems for the ITER experimental tokamak device. Due to their high power coupling efficiency and high plasma densities, helicon devices may be able to reduce power requirements and potentially remove the need for caesium. In helicon sources, the RF power can be coupled efficiently into the plasma and it has been previously observed that the application of a small magnetic field can lead to a significant increase in the plasma density. In this work, we investigate negative ion dynamics in a high-power (20 kW) helicon plasma source. The negative ion fraction is measured by probe-based laser photodetachment, electron density and temperature are determined by a Langmuir probe and tuneable diode laser absorption spectroscopy is used to determine the density of the H(n = 2) excited atomic state and the gas temperature. The negative ion density and excited atomic hydrogen density display a maximum at a low applied magnetic field of 3 mT, while the electron temperature displays a minimum. The negative ion density can be increased by a factor of 8 with the application of the magnetic field. Spatial and temporal measurements will also be presented. The Australian Research Grants Council is acknowledged for funding. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li class="active">14</li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_15" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li class="active">15</li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="281"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1991ApJ...374..374N','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1991ApJ...374..374N">Coronal magnetic structures observing campaign. I - Simultaneous microwave and soft X-ray observations of active regions at the solar limb</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Nitta, N.; White, S. M.; Kundu, M. R.; Gopalswamy, N.; Holman, G. D.; Brosius, J. W.; Schmelz, J. T.; Saba, J. L. R.; Strong, K. T. 1991-06-01 Using simultaneous microwave and soft X-ray measurements made with the Very Large Array (VLA) at 6 and 20 cm and the X-ray Polychromator (XRP) aboard the Solar Maximum Mission (SMM), we have studied two active regions near the solar limb. These observations were taken as part of the Coronal Magnetic Structures Observing Campaign (CoMStOC), a collaboration designed to study the magnetic field in the solar corona. The images in soft X-rays and at 20 cm wavelength are similar: both show peaks above the active regions and extended bridge of emission 200,000 km long connecting the two regions. The brightness temperature of the 20 cm emission is lower than that predicted from the X-ray emitting material, however; it can be attributed to free-free emission in cooler (<106 K) plasma not visible to XRP, with an optical depth ˜1. The 6 cm emission is concentrated at lower altitudes and in a ˜160,000 km long bundle of loops in the northern active region. Comparison of the 6 cm map with the potential magnetic field lines computed from photospheric magnetic fields (measured 2 days earlier) indicates that the 6 cm emission is associated with fields of less than ˜200 G. Such fields would be too weak to attribute the observed 6 cm emission to gyroresonance radiation. Analysis of the 6 cm loop bundle indicates that it is strongly asymmetric, with the magnetic field in the northern leg ˜2 times stronger than in the southern leg; the 6 cm emission most likely arises from a combination of hot ( ≥ 2 × 106 K) and cool plasmas, while the 20 cm emission becomes optically thick in the cooler (˜9 × 103 K) plasma. We estimate an Alfvén speed ˜7000 km s-1 and ratio of electron gyrofrequency to plasma frequency ˜1.0 in the northern leg of the 6 cm loop. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017Ap%26SS.362..101M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017Ap%26SS.362..101M">Energy budget during an isolated substorm using measurements of multi satellites and geomagnetic indices</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Ma, Yuduan; Yang, Jian; Dunlop, M. W.; An, An 2017-05-01 Measurements of multi satellites and geomagnetic indices are used to investigate the energy budget during an isolated substorm. The calculation of the energy transfer from the solar wind to the magnetosphere (parameter ɛ), the energy increase of the ring current (U_{{R}}), the Joule heating (U_{{J}}), the particle precipitation energy flux (U_{{A}}) and their time-integrated energy dissipation {W}_{ɛ}, {W}_{{R}}, {W}_{{J}}, {W}_{{A}} indicates that there should be energy dissipation such as plasma heating and the energy returned to the solar wind by plasmoid ejection from the tail. After calculating the spatial sizes of nine selected BBFs, the energy flux density and energy transported Earthward or tailward by BBFs, using observations from three satellites, are found to be different during an isolated substorm. The flow thermal energy is dominant whether the energy is transported Earthward or tailward under the frozen-in condition in the inner plasma sheet. From results simultaneously observed by three satellites in the magnetotail, we find that the Earthward energy transported by the flows can provide the energy dissipation of {W}_{{J}} and {W}_{{A}}, where the flows are Earthward for more than 60% of the samples, while the tailward energy transport is far larger than {U}_{{A}} and close to {U}_{{J}}, where the flows are tailward for less than 40% of the samples. The maximum energy flux density is observed by one satellite to be accompanied by large variations, while the maximum energy transport is observed by another satellite with large energy flux density and small variations. This suggests misleading conclusions would be obtained if there were only data from single (or two) satellites. From our results, BBFs play an important role in the process of energy transport both Earthward and tailward during this isolated substorm. Data based on observations from one satellite in the magnetotail could be easily misinterpreted and should be used cautiously. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20197971','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20197971">Beam deviation method as a diagnostic tool for the plasma focus.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Schmidt, H; Rückle, B 1978-04-15 The application of an optical method for density measurements in cylindrical plasmas is described. The angular deviation of a probing light beam sent through a plasma is proportional to the maximum of the density in the plasma column. The deviation does not depend on the plasma dimensions; however, it is influenced to a certain degree by the density profile. The method is successfully applied to the investigation of a dense plasma focus with a time resolution of 2 nsec and a spatial resolution (in axial direction) of 2 mm. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017PhPl...24d3505F','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017PhPl...24d3505F">Study on electromagnetic plasma propulsion using rotating magnetic field acceleration scheme</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Furukawa, T.; Takizawa, K.; Kuwahara, D.; Shinohara, S. 2017-04-01 As one of the electromagnetic plasma acceleration systems, we have proposed a rotating magnetic field (RMF) acceleration scheme to overcome the present problem of direct plasma-electrode interactions, leading to a short lifetime with a poor plasma performance due to contamination. In this scheme, we generate a plasma by a helicon wave excited by a radio frequency (rf) antenna which has no direct-contact with a plasma. Then, the produced plasma is accelerated by the axial Lorentz force fz = jθ × Br (jθ is an azimuthal current induced by RMF, and Br is an external radial magnetic field). Erosion of electrodes and contamination are not expected in this total system since RMF coils and an rf antenna do not have contact with the plasma directly. Here, we have measured the plasma parameters (electron density ne and axial ion velocity vi) to demonstrate this RMF acceleration scheme by the use of AC currents in two sets of opposing coils to generate a RMF. The maximum increasing rate Δvi /vi was ˜28% (maximum vi of ˜3 km/s), while the density increasing rate of Δne/ne is ˜ 70% in the case of a RMF current frequency fRMF of 3 MHz, which showed a better plasma performance than that with fRMF = 5 MHz. Moreover, thrust characteristics such as a specific impulse and a thrust efficiency were discussed, although a target plasma was not optimized. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018PlST...20d4001X','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018PlST...20d4001X">Measurement of cytoplasmic Ca2+ concentration in Saccharomyces cerevisiae induced by air cold plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Xiaoyu, DONG 2018-03-01 In this study, a novel approach to measure the absolute cytoplasmic Ca2+ concentration ([Ca2+]cyt) using the Ca2+ indicator fluo-3 AM was established. The parameters associated with the probe fluo-3 AM were optimized to accurately determine fluorescence intensity from the Ca2+-bound probe. Using three optimized parameters (final concentration of 6 mM probe, incubation time of 135 min, loading probe before plasma treatment), the maximum fluorescence intensity (F max = 527.8 a.u.) and the minimum fluorescence intensity (F min = 63.8 a.u.) were obtained in a saturated Ca2+ solution or a solution of lacking Ca2+. Correspondingly, the maximum [Ca2+]cyt induced by cold plasma was 1232.5 nM. Therefore, the Ca2+ indicator fluo-3 AM was successfully applied to measure the absolute [Ca2+]cyt in Saccharomyces cerevisiae stimulated by cold plasma at atmospheric air pressure. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JAP...123o3101S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JAP...123o3101S">Terahertz radiation generation through the nonlinear interaction of Hermite and Laguerre Gaussian laser beams with collisional plasma: Field profile optimization</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Safari, Samaneh; Niknam, Ali Reza; Jahangiri, Fazel; Jazi, Bahram 2018-04-01 The nonlinear interaction of Hermite-Gaussian and Laguerre-Gaussian (LG) laser beams with a collisional inhomogeneous plasma is studied, and the amplitude of the emitted terahertz (THz) electric field is evaluated. The effects of laser beams and plasma parameters, including the beams width, LG modes, the plasma collision frequency, and the amplitude of density ripple on the evolution of THz electric field amplitude, are examined. It is found that the shape of the generated THz radiation pattern can be tuned by the laser parameters. In addition, the optimum values of the effective parameters for achieving the maximum THz electric field amplitude are proposed. It is shown that a significant enhancement up to 4.5% can be obtained in our scheme, which is much greater than the maximum efficiency obtained for laser beams with the same profiles. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2004JPhD...37.1792H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2004JPhD...37.1792H">Time-dependent spectroscopy of plasma plume under laser welding conditions</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Hoffman, Jacek; Szymanski, Zygmunt 2004-07-01 Momentary emission spectra of iron and argon lines were measured in a plasma plume induced during welding with a continuous wave CO2 laser. Time-dependent spectra were registered using a fast gate, lens coupled microchannel plate image intensifier placed between a spectrograph and a 1254 silicon intensified target detector connected to an optical multichannel analyser. The results, together with the analysis of the colour images from a fast camera, show that in the case when argon is the shielding gas, two plasmas exist: the argon plasma and the iron plasma. It has been found that during strong bursts the plasma plume over the keyhole consists mainly of metal vapour, not being diluted by the shielding gas. No apparent mixing of the metal vapour and the shielding gas has been observed. The space-averaged electron densities determined from the Stark broadening of the 7503.87, 7514.65 Å Ar I lines amounts to (0.75-1.05) × 1023 m-3 depending on the distance from the surface. Assuming that argon is not mixed with the metal vapour and is in local thermodynamic equilibrium these electron densities correspond to the temperatures of 12-13 kK. At the peaks of strong vapour bursts the space-averaged electron densities determined from the Stark broadening of the 5383.37 Å Fe I line are (0.6-1) × 1023 m-3. Numerical simulations showed that the maximum densities in the plasma centre are considerably higher and amount to ~1.8 × 1023 m-3 and ~2.45 × 1023 m-3 in the case of the argon and metal plasma, respectively. Consequently the absorption of the laser beam in the plasma plume amounts to ~5% of the beam power in the case of argon and 10% in the case of metal plasma. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28197931','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28197931">Pharmacokinetics and Pharmacodynamics of Lysergic Acid Diethylamide in Healthy Subjects.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Dolder, Patrick C; Schmid, Yasmin; Steuer, Andrea E; Kraemer, Thomas; Rentsch, Katharina M; Hammann, Felix; Liechti, Matthias E 2017-10-01 Lysergic acid diethylamide (LSD) is used recreationally and in clinical research. The aim of the present study was to characterize the pharmacokinetics and exposure-response relationship of oral LSD. We analyzed pharmacokinetic data from two published placebo-controlled, double-blind, cross-over studies using oral administration of LSD 100 and 200 µg in 24 and 16 subjects, respectively. The pharmacokinetics of the 100-µg dose is shown for the first time and data for the 200-µg dose were reanalyzed and included. Plasma concentrations of LSD, subjective effects, and vital signs were repeatedly assessed. Pharmacokinetic parameters were determined using compartmental modeling. Concentration-effect relationships were described using pharmacokinetic-pharmacodynamic modeling. Geometric mean (95% confidence interval) maximum plasma concentration values of 1.3 (1.2-1.9) and 3.1 (2.6-4.0) ng/mL were reached 1.4 and 1.5 h after administration of 100 and 200 µg LSD, respectively. The plasma half-life was 2.6 h (2.2-3.4 h). The subjective effects lasted (mean ± standard deviation) 8.2 ± 2.1 and 11.6 ± 1.7 h for the 100- and 200-µg LSD doses, respectively. Subjective peak effects were reached 2.8 and 2.5 h after administration of LSD 100 and 200 µg, respectively. A close relationship was observed between the LSD concentration and subjective response within subjects, with moderate counterclockwise hysteresis. Half-maximal effective concentration values were in the range of 1 ng/mL. No correlations were found between plasma LSD concentrations and the effects of LSD across subjects at or near maximum plasma concentration and within dose groups. The present pharmacokinetic data are important for the evaluation of clinical study findings (e.g., functional magnetic resonance imaging studies) and the interpretation of LSD intoxication. Oral LSD presented dose-proportional pharmacokinetics and first-order elimination up to 12 h. The effects of LSD were related to changes in plasma concentrations over time, with no evidence of acute tolerance. NCT02308969, NCT01878942. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011JaJAP..50aAE03C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011JaJAP..50aAE03C">Behaviors of Absolute Densities of N, H, and NH3 at Remote Region of High-Density Radical Source Employing N2-H2 Mixture Plasmas</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Chen, Shang; Kondo, Hiroki; Ishikawa, Kenji; Takeda, Keigo; Sekine, Makoto; Kano, Hiroyuki; Den, Shoji; Hori, Masaru 2011-01-01 For an innovation of molecular-beam-epitaxial (MBE) growth of gallium nitride (GaN), the measurements of absolute densities of N, H, and NH3 at the remote region of the radical source excited by plasmas have become absolutely imperative. By vacuum ultraviolet absorption spectroscopy (VUVAS) at a relatively low pressure of about 1 Pa, we obtained a N atom density of 9×1012 cm-3 for a pure nitrogen gas used, a H atom density of 7×1012 cm-3 for a gas composition of 80% hydrogen mixed with nitrogen gas were measured. The maximum density 2×1013 cm-3 of NH3 was measured by quadruple mass spectrometry (QMS) at H2/(N2+H2)=60%. Moreover, we found that N atom density was considerably affected by processing history, where the characteristic instability was observed during the pure nitrogen plasma discharge sequentially after the hydrogen-containing plasma discharge. These results indicate imply the importance of establishing radical-based processes to control precisely the absolute densities of N, H, and NH3 at the remote region of the radical source. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22320338-evolution-titanium-residue-walls-plasma-etching-reactor-its-effect-polysilicon-etching-rate','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22320338-evolution-titanium-residue-walls-plasma-etching-reactor-its-effect-polysilicon-etching-rate">Evolution of titanium residue on the walls of a plasma-etching reactor and its effect on the polysilicon etching rate</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Hirota, Kosa, E-mail: hirota-kousa@sme.hitachi-hitec.com; Itabashi, Naoshi; Tanaka, Junichi 2014-11-01 The variation in polysilicon plasma etching rates caused by Ti residue on the reactor walls was investigated. The amount of Ti residue was measured using attenuated total reflection Fourier transform infrared spectroscopy with the HgCdTe (MCT) detector installed on the side of the reactor. As the amount of Ti residue increased, the number of fluorine radicals and the polysilicon etching rate increased. However, a maximum limit in the etching rate was observed. A mechanism of rate variation was proposed, whereby F radical consumption on the quartz reactor wall is suppressed by the Ti residue. The authors also investigated a plasma-cleaningmore » method for the removal of Ti residue without using a BCl{sub 3} gas, because the reaction products (e.g., boron oxide) on the reactor walls frequently cause contamination of the product wafers during etching. CH-assisted chlorine cleaning, which is a combination of CHF{sub 3} and Cl{sub 2} plasma treatment, was found to effectively remove Ti residue from the reactor walls. This result shows that CH radicals play an important role in deoxidizing and/or defluorinating Ti residue on the reactor walls.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017LaPhy..27d6101I','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017LaPhy..27d6101I">Time integrated optical emission studies of the laser produced germanium plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Iqbal, Javed; Ahmed, R.; Baig, M. A. 2017-04-01 We present new time integrated data on the optical emission spectra of laser produced germanium plasma using a Q-switched Nd:YAG laser (1064 nm), power density up to about 5 × 109 W cm-2 in conjunction with a set of five spectrometers covering a spectral range from 200 nm to 720 nm. Well resolved structure due to the 4p5s → 4p2 transition array of neutral germanium and a few multiplets of singly ionized germanium have been observed. Plasma temperature has been determined in the range (9000-11 000) K using four different techniques; two line ratio method, Boltzmann plot, Saha-Boltzmann plot and Marotta’s technique whereas electron density has been deduced from the Stark broadened line profiles in the range (0.5-5.0) × 1017 cm-3, depending on the laser pulse energy to produce the germanium plasma. Full width at half maximum (FWHM) of a number of neutral and singly ionized germanium lines have been extracted by the Lorentzian fit to the experimentally observed line profiles. In addition, we have compared the experimentally measured relative line strengths for the 4p5s 3P0,1,2 → 4p2 3P0,1,2 multiplet with that calculated in the LS-coupling scheme revealing that the intermediate coupling scheme is more appropriate for the level designations in germanium. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016cosp...41E1082K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016cosp...41E1082K">Study of large Forbush decreases in cosmic-ray intensity observed during solar cycle 23 and 24</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kumar, Anand; Badruddin, B. 2016-07-01 Neutron monitors at different geomagnetic latitude and longitude of Earth measure the cosmic-ray intensity with high precision. Sudden decreases in cosmic-ray intensity within few hours and slow recovery to pre-decrease level within a few days (Forbush decreases) are observed in neutron monitor data. We identify large-amplitude Forbush decreases (FDs), using high counting rate neutron monitor data, that occurred during previous solar cycle 23 (1995-2009) and current solar cycle 24 (2010-2015). We then search for the solar sources and the interplanetary structures responsible for these decreases. We attempt to find the relative importance of various interplanetary plasma and field parameters and the physical mechanism(s) responsible for FDs of varying amplitudes. We analyze a number of interplanetary plasma and field parameters, during both the phases (main and recovery) of FDs. The interplanetary plasma and field data analyzed in this study are the solar-wind velocity, the interplanetary magnetic field, its fluctuations, interplanetary electric field and the time variation of interplanetary electric potential. For monitoring the changes in interplanetary plasma/field conditions during the development of FDs, we also utilize plasma density, temperature and plasma beta, dynamic pressure and Mach number during the passage of interplanetary structures responsible for FDs. In addition to their amplitude, we study the recovery of FDs in detail after determining the time constant during their recovery by exponential fit to the data. As the solar magnetic polarity reversed during the maximum phase of solar cycle 23 (in the year 2000), we study the differences in amplitude, time constant of recovery and plasma/field condition to search for the polarity dependent effects, if any, on the amplitude and recovery of FDs due to implication for the models suggested to explain the Forbush decrease phenomena. The implications of these results are discussed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22617157-new-scenario-saturation-low-threshold-two-plasmon-parametric-decay-instability-extraordinary-wave-inhomogeneous-plasma-magnetic-traps','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22617157-new-scenario-saturation-low-threshold-two-plasmon-parametric-decay-instability-extraordinary-wave-inhomogeneous-plasma-magnetic-traps">On a new scenario for the saturation of the low-threshold two-plasmon parametric decay instability of an extraordinary wave in the inhomogeneous plasma of magnetic traps</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Gusakov, E. Z., E-mail: Evgeniy.Gusakov@mail.ioffe.ru; Popov, A. Yu., E-mail: a.popov@mail.ioffe.ru; Irzak, M. A., E-mail: irzak@mail.ioffe.ru The most probable scenario for the saturation of the low-threshold two-plasmon parametric decay instability of an electron cyclotron extraordinary wave has been analyzed. Within this scenario two upperhybrid plasmons at frequencies close to half the pump wave frequency radially trapped in the vicinity of the local maximum of the plasma density profile are excited due to the excitation of primary instability. The primary instability saturation results from the decays of the daughter upper-hybrid waves into secondary upperhybrid waves that are also radially trapped in the vicinity of the local maximum of the plasma density profile and ion Bernstein waves. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19980228276','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19980228276">Sporadic-E As Observed with Rockets</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Seddon, J. Carl 1961-01-01 Data obtained with rockets flown over New Mexico, U.S.A. and Manitoba, Canada have always shown the sporadic-E layer to be a thin layer with a large electron density gradient. The vertical electron density profiles and the horizontal uniformity of the sporadic-E layer are discussed herein. These layers have a strong tendency to form at preferential altitudes separated by approximately 6 km, and a striking correlation exists with wind- shears and magnetic field variations. In two cases where comparisons with ionograms were possible, the minimum frequency of the F-region echoes was found approximately equal to the plasma frequency of the sporadic-E layer reduced by half the gyrofrequency. On the other hand, the maximum frequency of the sporadic-E echoes as noted on ionograms was sometimes as much as 1 to 2 Mc greater than the plasma frequency. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010JGRA..115.9315A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010JGRA..115.9315A">Midnight latitude-altitude distribution of 630 nm airglow in the Asian sector measured with FORMOSAT-2/ISUAL</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Adachi, Toru; Yamaoka, Masashi; Yamamoto, Mamoru; Otsuka, Yuichi; Liu, Huixin; Hsiao, Chun-Chieh; Chen, Alfred B.; Hsu, Rue-Ron 2010-09-01 The Imager for Sprites and Upper Atmospheric Lightning (ISUAL) payload on board the FORMOSAT-2 satellite carried out the first limb imaging observation of 630 nm airglow for the purpose of studying physical processes in the F region ionosphere. For a total of 14 nights in 2006-2008, ISUAL scanned the midnight latitude-altitude distribution of 630 nm airglow in the Asian sector. On two nights of relatively active conditions (ΣKp = 26, 30+) we found several bright airglow regions, which were highly variable each night in terms of luminosity and location. In relatively quiet conditions (ΣKp = 4-20) near May/June we found two bright regions which were stably located in the midlatitude region of 40°S-10°S (50°S-20°S magnetic latitude (MLAT)) and in the equatorial region of 0°-10°N (10°S-0° MLAT). On one of the quiet nights, FORMOSAT-3/COSMIC and CHAMP simultaneously measured the plasma density in the same region where ISUAL observed airglow. The plasma density data generally show good agreement, suggesting that plasma enhancements were the primary source of these two bright airglow regions. From detailed comparison with past studies we explain that the airglow in the equatorial region was due to the midnight brightness wave produced in association with the midnight temperature maximum, while that in the midlatitude region was due to the typical plasma distribution usually formed in the midnight sector. The fact that the equatorial airglow was much brighter than the midlatitude airglow and was observed on most nights during the campaign period strongly suggests the importance of further studies on the MTM/MBW phenomenology, which is not well reproduced in the current general circulation model. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22403326-spectroscopic-measurement-high-frequency-electric-fields-interaction-explosive-debris-plasma-magnetized-background-plasma','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22403326-spectroscopic-measurement-high-frequency-electric-fields-interaction-explosive-debris-plasma-magnetized-background-plasma"></a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Bondarenko, A. S., E-mail: AntonBondarenko@ymail.com; Schaeffer, D. B.; Everson, E. T. The collision-less transfer of momentum and energy from explosive debris plasma to magnetized background plasma is a salient feature of various astrophysical and space environments. While much theoretical and computational work has investigated collision-less coupling mechanisms and relevant parameters, an experimental validation of the results demands the measurement of the complex, collective electric fields associated with debris-background plasma interaction. Emission spectroscopy offers a non-interfering diagnostic of electric fields via the Stark effect. A unique experiment at the University of California, Los Angeles, that combines the Large Plasma Device (LAPD) and the Phoenix laser facility has investigated the marginally super-Alfvénic, quasi-perpendicularmore » expansion of a laser-produced carbon (C) debris plasma through a preformed, magnetized helium (He) background plasma via emission spectroscopy. Spectral profiles of the He II 468.6 nm line measured at the maximum extent of the diamagnetic cavity are observed to intensify, broaden, and develop equally spaced modulations in response to the explosive C debris, indicative of an energetic electron population and strong oscillatory electric fields. The profiles are analyzed via time-dependent Stark effect models corresponding to single-mode and multi-mode monochromatic (single frequency) electric fields, yielding temporally resolved magnitudes and frequencies. The proximity of the measured frequencies to the expected electron plasma frequency suggests the development of the electron beam-plasma instability, and a simple saturation model demonstrates that the measured magnitudes are feasible provided that a sufficiently fast electron population is generated during C debris–He background interaction. Potential sources of the fast electrons, which likely correspond to collision-less coupling mechanisms, are briefly considered.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26566193','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26566193">Efficacy of pharmacokinetic interactions between piperonyl butoxide and albendazole against gastrointestinal nematodiasis in goats.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Kumbhakar, N K; Sanyal, P K; Rawte, D; Kumar, D; Kerketta, A E; Pal, S 2016-09-01 To test the hypothesis that modulation of hepatic microsomal sulphoxidation and sulphonation by the cytochrome P450 inhibitor piperonyl butoxide could increase bioavailability of albendazole, the present study was undertaken to understand the pharmacokinetics of albendazole in goats at a dose of 7.5 mg kg- 1 body weight with and without co-administration with piperonyl butoxide at 63.0 mg kg- 1 body weight. Plasma albendazole sulphoxide metabolite, the anthelmintically active moiety, reached its maximum concentration of 0.322 ± 0.045 μg ml- 1 and 0.384 ± 0.013 μg ml- 1 at 18 h and 24 h after administration of albendazole alone and co-administration of albendazole with piperonyl butoxide, respectively. Analysis of the data revealed statistically increased albendazole sulphoxide levels at 24 (P 0.05) in values of maximum concentration (normal and calculated) could be observed between groups of goats. However, values of time to reach the concentration maximum (normal and calculated), area under the concentration-time curve (0-∞ and calculated), minimum residence time, distribution half-life, elimination half-life and total area under the first movement of plasma drug concentration-time curve were significantly higher (P < 0.05) in plasma levels of albendazole sulphoxide in goats following single oral co-administration of albendazole with piperonyl butoxide. The faecal egg count reduction and lower 95% confidence limit for the group treated with albendazole alone were 97 and 68%, while for co-administration of albendazole and piperonyl butoxide the values were 99 and 97%, respectively. The ED50 for egg hatch was 0.196, indicating suspected resistance to benzimidazole anthelmintics. The drug combination proved efficacious against an albendazole-resistant nematode parasite population in goats. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3809861','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3809861">Autologous Platelet-Poor Plasma Gel for Injection Laryngoplasty</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Woo, Seung Hoon; Kim, Jin Pyeong; Park, Jung Je; Chung, Phil-Sang 2013-01-01 Purpose To overcome the potential disadvantages of the use of foreign materials and autologous fat or collagen, we introduce here an autologous plasma gel for injection laryngoplasty. The purpose of this study was to present a new injection material, a plasma gel, and to discuss its clinical effectiveness. Materials and Methods From 2 mL of blood, the platelet poor serum layer was collected and heated at 100℃ for 12 min to form a plasma gel. The plasma gel was then injected into a targeted site; the safety and efficacy thereof were evaluated in 30 rats. We also conducted a phase I/II clinical study of plasma gel injection laryngoplasty in 11 unilateral vocal fold paralysis patients. Results The plasma gel was semi-solid and an easily injectable material. Of note, plasma gel maintains the same consistency for up to 1 year in a sealed bottle. However, exposure to room air causes the plasma gel to disappear within 1 month. In our animal study, the autologous plasma gel remained in situ for 6 months in animals with minimal inflammation. Clinical study showed that vocal cord palsy was well compensated for with the plasma gel in all patients at two months after injection with no significant complications. Jitter, shimmer, maximum, maximum phonation time (MPT) and mean voice handicap index (VHI) also improved significantly after plasma gel injection. However, because the injected plasma gel was gradually absorbed, 6 patients needed another injection, while the gel remained in place in 2 patients. Conclusion Injection laryngoplasty with autologous plasma gel may be a useful and safe treatment option for temporary vocal cord palsy. PMID:24142660 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1981soac.rept.....B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1981soac.rept.....B">Spectroscopic diagnostics of solar flares</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Bely-Dubau, F.; Dubau, J.; Faucher, P.; Loulergue, M.; Steenman-Clarke, L. Observations made with the X-ray polychromator (XRP) on board the Solar Maximum Mission satellite were analyzed. Data from the bent crystal spectrometer portion of the XRP experiment, in the spectral domain 1 to 3 A, with high spectral and temporal resolution, were used. Results for the spectrum analysis of iron are given. The possibility of polarization effects is considered. Although it is demonstrated that hyperfine analyses of a given spectrum are obtainable, provided calculations include large quantities of high precision atomic data, the interpretation is limited by the hypothesis of homogeneity of the emitting plasma. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012JGRA..117.6230O','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012JGRA..117.6230O">Flow stagnation at Enceladus: The effects of neutral gas and charged dust</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Omidi, N.; Tokar, R. L.; Averkamp, T.; Gurnett, D. A.; Kurth, W. S.; Wang, Z. 2012-06-01 Enceladus is one of Saturn's most active moons. It ejects neutral gas and dust particles from its southern plumes with velocities of hundreds of meters per second. The interaction between the ejected material and the corotating plasma in Saturn's magnetosphere leads to flow deceleration in ways that remain to be understood. The most effective mechanism for the interaction between the corotating plasma and the neutral gas is charge exchange which replaces the hotter corotating ions with nearly stationary cold ions that are subsequently accelerated by the motional electric field. Dust particles in the plume can become electrically charged through electron absorption and couple to the plasma through the motional electric field. The objective of this study is to determine the level of flow deceleration associated with each of these processes using Cassini RPWS dust impact rates, Cassini Plasma Spectrometer (CAPS) plasma data, and 3-D electromagnetic hybrid (kinetic ions, fluid electrons) simulations. Hybrid simulations show that the degree of flow deceleration by charged dust varies considerably with the spatial distribution of dust particles. Based on the RPWS observations of dust impacts during the E7 Cassini flyby of Enceladus, we have constructed a dust model consisting of multiple plumes. Using this model in the hybrid simulation shows that when the dust density is high enough for complete absorption of electrons at the point of maximum dust density, the corotating flow is decelerated by only a few km/s. This is not sufficient to account for the CAPS observation of flow stagnation in the interaction region. On the other hand, charge exchange with neutral gas plumes similar to the modeled dust plumes but with base (plume opening) densities of ˜109 cm-3 result in flow deceleration similar to that observed by CAPS. The results indicate that charge exchange with neutral gas is the dominant mechanism for flow deceleration at Enceladus. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li class="active">15</li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_16" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li class="active">16</li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="301"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19930013367','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19930013367">Characterization and durability testing of plasma-sprayed zirconia-yttria and hafnia-yttria thermal barrier coatings. Part 1: Effect of spray parameters on the performance of several lots of partially stabilized zirconia-yttria powder</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Miller, Robert A.; Leissler, George W.; Jobe, J. Marcus 1993-01-01 Initial experiments conducted on thermal barrier coatings prepared in the newly upgraded research plasma spray facility and the burner rig test facilities are discussed. Part 1 discusses experiments which establish the spray parameters for three baseline zirconia-yttria coatings. The quality of five similar coating lots was judged primarily by their response to burner rig exposure supplemented by data from other sources such as specimen characterizations and thermal diffusivity measurements. After allowing for burner rig variability, although there appears to be an optimum density (i.e., optimum microstructure) for maximum burner rig life, the distribution tends to be rather broad about the maximum. In Part 2, new hafnia-yttria-based coatings were evaluated against both baseline and alternate zirconia-yttria coatings. The hafnia-yttria coatings and the zirconia-yttria coatings that were prepared by an alternate powder vendor were very sensitive to plasma spray parameters, in that high-quality coatings were only obtained when certain parameters were employed. The reasons for this important observation are not understood. Also not understood is that the first of two replicate specimens sprayed for Part 1 consistently performed better than the second specimen. Subsequent experiments did not display this spray order affect, possibly because a chiller was installed in the torch cooling water circuit. Also, large changes in coating density were observed after switching to a new lot of electrodes. Analyses of these findings were made possible, in part, because of the development of a sensitive density measurement technique described herein in detail. The measured thermal diffusivities did not display the expected strong relationship with porosity. This surprising result was believed to have been caused by increased microcracking of the denser coatings on the stainless steel substrates. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/20040171605','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20040171605">On the Origin of Whistler Mode Radiation in the Plasmasphere</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Green, James L.; Boardsen, Scott; Garcia, Leonard; Taylor, W. W. L.; Fung, Shing F.; Reinisch, B. W. 2004-01-01 The origin of whistler mode radiation in the plasmasphere is examined from three years of plasma wave observations from the Dynamics Explorer and three years from the Imager for Magnetopause-to-Aurora Global Exploration (IMAGE) spacecraft. These data are used to construct plasma wave intensity maps of whistler mode radiation in the plasmasphere. The highest average intensities of the radiation in the wave maps show source locations and/or sites of wave amplification. Each type of emission is classified based on its magnetic latitude and longitude rather than any spectral feature. Equatorial electromagnetic (EM) emissions (approx. 30-330 Hz), plasmaspheric hiss (approx. 330 Hz - 3.3 kHz), chorus (approx. 2 kHz - 6 kHz), and VLF transmitters (approx. 10-50 kHz) are the main types of waves that are clearly delineated in the plasma wave maps. Observations of the equatorial EM emissions show that the most intense region is on or near the magnetic equator in the afternoon sector and that during times of negative B(sub z) (interplanetary magnetic field),the maximum intensity moves from L values of 3 to less than 2. These observations are consistent with the origin of this emission being particle-wave interactions in or near the magnetic equator. Plasmaspheric hiss shows high intensity at high latitudes and low altitudes (L shells from 2 to 4) and in the magnetic equator over L values from 2 to 3 in the early afternoon sector. The longitudinal distribution of the hiss intensity (excluding the enhancement at the equator) is similar to the distribution of lightning: stronger over continents than over the ocean, stronger in the summer than winter, and stronger on the dayside than nightside. These observations strongly support lightning as the dominant source for plasmaspheric hiss, which through particle-wave interactions, maintains the slot region in the radiation belts. The enhancement of hiss at the magnetic equator is consistent with particle-wave interactions. The chorus emissions are most intense on the morning side as previously reported. At frequencies from approx. 10-50 kHz VLF transmitters dominate the spectrum. The maximum intensity of the VLF transmitters is in the late evening or early morning with enhancements all along L shells from 1.8 to 3. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA164298','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA164298">Operational Characteristics of a High Voltage Dense Plasma Focus.</a> <a target="_blank" rel="noopener noreferrer" href="http://www.dtic.mil/">DTIC Science & Technology</a> 1985-11-01 A high voltage dense plasma focus powered by a single-stage Marx bank was designed, built and operated. The maximum bank parameters are: voltage--120...kV, energy--20 kJ, short-circuit current--600kA. The bank impedance is about 200 millohms. The plasma focus center electrode diameter is 1.27 cm. The...about 50 milliohms. The context of this work is established with a review of previous plasma focus theoretical, experimental and computational work and </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018PlST...20a4013F','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018PlST...20a4013F">Development and experimental study of large size composite plasma immersion ion implantation device</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Falun, SONG; Fei, LI; Mingdong, ZHU; Langping, WANG; Beizhen, ZHANG; Haitao, GONG; Yanqing, GAN; Xiao, JIN 2018-01-01 Plasma immersion ion implantation (PIII) overcomes the direct exposure limit of traditional beam-line ion implantation, and is suitable for the treatment of complex work-piece with large size. PIII technology is often used for surface modification of metal, plastics and ceramics. Based on the requirement of surface modification of large size insulating material, a composite full-directional PIII device based on RF plasma source and metal plasma source is developed in this paper. This device can not only realize gas ion implantation, but also can realize metal ion implantation, and can also realize gas ion mixing with metal ions injection. This device has two metal plasma sources and each metal source contains three cathodes. Under the condition of keeping the vacuum unchanged, the cathode can be switched freely. The volume of the vacuum chamber is about 0.94 m3, and maximum vacuum degree is about 5 × 10-4 Pa. The density of RF plasma in homogeneous region is about 109 cm-3, and plasma density in the ion implantation region is about 1010 cm-3. This device can be used for large-size sample material PIII treatment, the maximum size of the sample diameter up to 400 mm. The experimental results show that the plasma discharge in the device is stable and can run for a long time. It is suitable for surface treatment of insulating materials. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014APS..DPPCP8091E','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014APS..DPPCP8091E">Dropper for micron and submicron size powders for a plasma mass filter</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Evans, Eugene S.; Zweben, Stewart J.; Gueroult, Renaud; Fisch, Nathaniel J.; Levinton, Fred 2014-10-01 The goal of the Plasma Mass Filter (PMF) experiment at PPPL, in collaboration with Nova Photonics, Inc., is to achieve separation between high-Z and low-Z atoms, for possible application to processing of nuclear waste to remove the highly radioactive high-Z components. The PMF features a rotating plasma column in which centrifugal forces push high-mass ions out of the plasma radially, while low-mass ions exit the plasma axially. In order to control the injection location, high-Z materials are introduced in powder form into the PMF plasma. The current experiment is limted to ~1 kW RF, giving a calculated maximum flow rate of ~0.1 mg/s. An electron temperature of a few eV and assumptions about the residence time of the dust particles in the PMF plasma limits the calculated maximum particle size to ~1 μm. While previous dusty plasma experiments have dealt with particles on the order of 2-3 μm, submicron particles are comparatively more difficult to manipulate under vacuum due to increased Van Der Waals and electrostatic forces. A powder dropper capable of reliably dropping micron and submicron-size particles at this flow rate is being developed, consisting of a mesh-bottomed container that is coupled to vibration motors. This work supported by DOE contract DE-AC02-09CH11466. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017NucFu..57k6026S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017NucFu..57k6026S">Enhanced reproducibility of L-mode plasma discharges via physics-model-based q-profile feedback control in DIII-D</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Schuster, E.; Wehner, W. P.; Barton, J. E.; Boyer, M. D.; Luce, T. C.; Ferron, J. R.; Holcomb, C. T.; Walker, M. L.; Humphreys, D. A.; Solomon, W. M.; Penaflor, B. G.; Johnson, R. D. 2017-11-01 Recent experiments on DIII-D demonstrate the potential of physics-model-based q-profile control to improve reproducibility of plasma discharges. A combined feedforward + feedback control scheme is employed to optimize the current ramp-up phase by consistently achieving target q profiles (Target 1: q_min=1.3, q95=4.4 ; Target 2: q_min=1.65, q95=5.0 ; Target 3: q_min=2.1, q95=6.2 ) at prescribed times during the plasma formation phase (Target 1: t=1.5 s; Target 2: t=1.3 s; Target 3: t=1.0 s). At the core of the control scheme is a nonlinear, first-principles-driven, physics-based, control-oriented model of the plasma dynamics valid for low confinement (L-mode) scenarios. To prevent undesired L-H transitions, a constraint on the maximum allowable total auxiliary power is imposed in addition to the maximum powers for the individual heating and current-drive sources. Experimental results are presented to demonstrate the effectiveness of the combined feedforward + feedback control scheme to consistently achieve the desired target profiles at the predefined times. These results also show how the addition of feedback control significantly improves upon the feedforward-only control solution by reducing the matching error and also how the feedback controller is able to reduce the matching error as the constraint on the maximum allowable total auxiliary power is relaxed while keeping the plasma in L-mode. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/12033516','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/12033516">Pharmacokinetics and pharmacodynamics of human chorionic gonadotropin (hCG) after rectal administration of hollow-type suppositories containing hCG.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Kowari, Kouji; Hirosawa, Iori; Kurai, Hirono; Utoguchi, Naoki; Fujii, Makiko; Watanabe, Yoshiteru 2002-05-01 To determine the effectiveness of human chorionic gonadotropin (hCG) administered rectally, we studied the pharmacokinetics and pharmacodynamics of hCG using a hollow-type suppository. HCG was not detected in plasma when only hCG was administered rectally, even at a higher dose (4,000 IU/kg body weight) than intravenous injection, because of its low bioavailability due to high molecular weight or degradation by proteolytic activity. To enhance the rectal absorption of hCG, the effectiveness of its coadministration with alpha-cyclodextrin (alpha-CyD), an absorption-enhancing agent, was investigated in male rabbits. HCG was detected in plasma following coadministration of hCG and alpha-CyD (10 mg/kg body weight) into the rectum. The plasma hCG concentration increased with increasing dose of alpha-CyD. The AUC(0-48) observed after coadministration of hCG and alpha-CyD at 30 mg/kg body weight was approximately four times higher than that of hCG and alpha-CyD at 10mg/kg body weight. HCG at a high concentration induced a rapid increase in the plasma testosterone concentration (74.2 +/- 3.4 ng/ml) 2 h after intravenous administration. However, the testosterone concentration 24 h after intravenous administration decreased to the physiological level (approximately 20 ng/ml) which had been observed before such administration. On the other hand, the maximum level of testosterone concentration (40.0 +/- 12.6 ng/ml) was observed 24 h after rectal administration of hCG (400 IU/kg body weight) in combination with alpha-CyD (30 mg/kg body weight). Moreover, the plasma testosterone concentration (31.0 +/- 11.4 ng/ml) obtained 72 h after rectal administration tended to be maintained at a higher level than that (14.4 +/- 0.9ng/ml) observed before the administration. These results suggest that the hollow-type suppository as a rectal delivery system of hCG is promising as a new mode of hCG therapy. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JAP...120q3104E','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JAP...120q3104E">Dynamics of low- and high-Z metal ions emitted during nanosecond laser-produced plasmas</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Elsied, Ahmed M.; Diwakar, Prasoon K.; Polek, Mathew; Hassanein, Ahmed 2016-11-01 Dynamics of metal ions during laser-produced plasmas was studied. A 1064 nm, Nd: YAG laser pulse was used to ablate pure Al, Fe, Co, Mo, and Sn samples. Ion flux and velocity were measured using Faraday cup ion collector. Time-of-flight measurements showed decreasing ion flux and ion velocity with increasing atomic weight, and heavy metal ion flux profile exhibited multiple peaks that was not observed in lighter metals. Slow peak was found to follow shifted Maxwell Boltzmann distribution, while the fast peak was found to follow Gaussian distribution. Ion flux angular distribution that was carried out on Mo and Al using fixed laser intensity 2.5 × 1010 W/cm2 revealed that the slow ion flux peaks at small angles, that is, close to normal to the target ˜0° independent of target's atomic weight, and fast ion flux for Mo peaks at large angles ˜40° measured from the target normal, while it completely absents for Al. This difference in spatial and temporal distribution reveals that the emission mechanism of the fast and slow ions is different. From the slow ion flux angular distribution, the measured plume expansion ratio (plume forward peaking) was 1.90 and 2.10 for Al and Mo, respectively. Moreover, the effect of incident laser intensity on the ion flux emission as well as the emitted ion velocity were investigated using laser intensities varying from 2.5 × 1010 W/cm2 to 1.0 × 1011 W/cm2. Linear increase of fast ion flux and velocity, and quadratic increase of slow ion flux and velocity were observed. For further understanding of plume dynamics, laser optical emission spectroscopy was used to characterize Sn plasma by measuring the temporal and spatial evolution of plasma electron density Ne and electron temperature Te. At 3.5 mm away from the target, plasma density showed slow decrease with time, however electron temperature was observed to decrease dramatically. The maximum plasma density and temperature occurred at 0.5 mm away from target and were measured to be 8.0 × 1017 cm-3 and 1.3 eV, respectively. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22614042-measurement-ion-beam-angular-distribution-different-helium-gas-pressures-plasma-focus-device-large-area-polycarbonate-detectors','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22614042-measurement-ion-beam-angular-distribution-different-helium-gas-pressures-plasma-focus-device-large-area-polycarbonate-detectors">Measurement of ion beam angular distribution at different helium gas pressures in a plasma focus device by large-area polycarbonate detectors</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Sohrabi, M.; Habibi, M., E-mail: mortezahabibi@gmail.com; Ramezani, V. 2017-02-15 The paper presents an experimental study and analysis of full helium ion density angular distributions in a 4-kJ plasma focus device (PFD) at pressures of 10, 15, 25, and 30 mbar using large-area polycarbonate track detectors (PCTDs) (15-cm etchable diameter) processed by 50-Hz-HV electrochemical etching (ECE). Helium ion track distributions at different pressures, in particular, at the main axis of the PFD are presented. Maximum ion track density of ~4.4 × 10{sup 4} tracks/cm{sup 2} was obtained in the PCTD placed 6 cm from the anode. The ion distributions for all pressures applied are ring-shaped, which is possibly due tomore » the hollow cylindrical copper anode used. The large-area PCTD processed by ECE proves, at the present state-of-theart, a superior method for direct observation and analysis of ion distributions at a glance with minimum efforts and time. Some observations of the ion density distributions at different pressures are reported and discussed.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19860055344&hterms=Dwarf+stars&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3DDwarf%2Bstars','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19860055344&hterms=Dwarf+stars&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3DDwarf%2Bstars">Millisecond radio spikes from the dwarf M flare star AD Leonis</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Lang, K. R.; Willson, R. F. 1986-01-01 Arecibo radio observations of millisec bursts of radio signals at 1415 MHz from AD Leonis are reported. The observed burst had an ellipticity of 0.95, 50-100 percent circular polarization, and a flux density maximum of 30 mJy. The 50 sec burst featured five quasi-periodic oscillations with a mean periodicity of about 3.2 sec. A second, less intense burst that occurred 20 sec later was 100 percent circularly polarized. The area emitting the bursts covered an estimated 0.005 of the radius of AD Leonis and had an electron density of 6 billion/cu cm and a longitudinal magnetic field strength of 250 gauss, if the source was an electron-cyclotron maser. A coherent plasma source would require, for the first harmonic, an electron density of 20 billion/cu cm and a magnetic field much less than 500 gauss. A second harmonic of the plasma frequency would require an electron density of 6 billion/cu cm and a field strength much less than 250 gauss. The possibility that the source was periodic oscillations in coronal loops is discussed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JAP...120r3302T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JAP...120r3302T">Modelling of crater formation on anode surface by high-current vacuum arcs</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Tian, Yunbo; Wang, Zhenxing; Jiang, Yanjun; Ma, Hui; Liu, Zhiyuan; Geng, Yingsan; Wang, Jianhua; Nordlund, Kai; Djurabekova, Flyura 2016-11-01 Anode melting and crater formation significantly affect interruption of high-current vacuum arcs. The primary objective of this paper is to theoretically investigate the mechanism of anode surface crater formation, caused by the combined effect of surface heating during the vacuum arc and pressure exerted on the molten surface by ions and electrons from the arc plasma. A model of fluid flow and heat transfer in the arc anode is developed and combined with a magnetohydrodynamics model of the vacuum arc plasma. Crater formation is observed in simulation for a peak arcing current higher than 15 kA on 40 mm diam. Cu electrodes spaced 10 mm apart. The flow of liquid metal starts after 4 or 5 ms of arcing, and the maximum velocities are 0.95 m/s and 1.39 m/s for 20 kA and 25 kA arcs, respectively. This flow redistributes thermal energy, and the maximum temperature of the anode surface does not remain in the center. Moreover, the condition for the liquid droplet formation on the anode surfaces is developed. The solidification process after current zero is also analyzed. The solidification time has been found to be more than 3 ms after 25 kA arcing. The long solidification time and sharp features on crater rims induce Taylor cone formation. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28442057','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28442057">Follicle vascularity coordinates corpus luteum blood flow and progesterone production.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> de Tarso, S G S; Gastal, G D A; Bashir, S T; Gastal, M O; Apgar, G A; Gastal, E L 2017-03-01 Colour Doppler ultrasonography was used to compare the ability of preovulatory follicle (POF) blood flow and its dimensions to predict the size, blood flow and progesterone production capability of the subsequent corpus luteum (CL). Cows (n=30) were submitted to a synchronisation protocol. Follicles ≥7mm were measured and follicular wall blood flow evaluated every 12h for approximately 3.5 days until ovulation. After ovulation, cows were scanned daily for 8 days and similar parameters were evaluated for the CL. Blood samples were collected and plasma progesterone concentrations quantified. All parameters were positively correlated. Correlation values ranged from 0.26 to 0.74 on data normalised to ovulation and from 0.31 to 0.74 on data normalised to maximum values. Correlations between calculated ratios of both POF and CL in data normalised to ovulation and to maximum values ranged from moderate (0.57) to strong (0.87). Significant (P<0.0001) linear regression analyses were seen in all comparisons. In conclusion, higher correlations were observed between the dimensions of POF and/or CL and blood flow of both structures, as well as POF and/or CL blood flow with plasma progesterone concentrations of the resultant CL. These findings indicate that follicle vascularity coordinates CL blood flow and progesterone production in synchronised beef cows. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/21075576-influence-damping-proton-energy-loss-plasmas-all-degeneracies','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/21075576-influence-damping-proton-energy-loss-plasmas-all-degeneracies">Influence of damping on proton energy loss in plasmas of all degeneracies</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Barriga-Carrasco, Manuel D. 2007-07-15 The purpose of the present paper is to describe the effects of electron-electron collisions on the stopping power of plasmas of any degeneracy. Plasma targets are considered fully ionized so electronic stopping is only due to the free electrons. We focus our analysis on plasmas which electronic density is around solid values n{sub e}{approx_equal}10{sup 23} cm{sup -3} and which temperature is around T{approx_equal}10 eV; these plasmas are in the limit of weakly coupled plasmas. This type of plasma has not been studied extensively though it is very important for inertial confinement fusion. The electronic stopping is obtained from an exactmore » quantum mechanical evaluation, which takes into account the degeneracy of the target plasma, and later it is compared with common classical and degenerate approximations. Differences are around 30% in some cases which can produce bigger mistakes in further energy deposition and projectile range studies. Then we consider electron-electron collisions in the exact quantum mechanical electronic stopping calculation. Now the maximum stopping occurs at velocities smaller than for the calculations without considering collisions for all kinds of plasmas analyzed. The energy loss enhances for velocities smaller than the velocity at maximum while decreases for higher velocities. Latter effects are magnified with increasing collision frequency. Differences with the same results for the case of not taking into account collisions are around 20% in the analyzed cases.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2004APS..DPPNO1014K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2004APS..DPPNO1014K">X-Ray generation in strongly nonlinear plasma waves.</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kiselev, Sergey; Pukhov, Alexander; Kostyukov, Igor 2004-11-01 Using three-dimensional particle-in-cell simulations we show that a strongly nonlinear plasma wave excited by an ultrahigh intensity laser pulse works as a compact high-brightness source of Xray radiation. It has been recently suggested by A. Pukhov and J. Meyer-ter-Vehn, Appl. Phys. B 74, 355 (2002), that in a strongly nonlinear regime the plasma wave transforms to a ``bubble'', which is almost free from background electrons. Inside the bubble, a dense bunch of relativistic electrons is produced. These accelerated electrons make betatron oscillations in the transverse fields of the bubble and emit a bright broadband X-ray radiation with a maximum about 50 keV. The emission is confined to a small angle of about 0.1 rad. In addition, we make simulations of X-ray generation by an external 28.5-GeV electron bunch injected into the bubble. Gamma-quanta with up to GeV energies are observed in the simulation in a good agreement with analytical results. The energy conversion is efficient, leading to a significant stopping of the electron bunch over 5 mm interaction distance. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/20764462-plasma-density-behavior-new-graphite-limiters-hefei-tokamak','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/20764462-plasma-density-behavior-new-graphite-limiters-hefei-tokamak">Plasma density behavior with new graphite limiters in the Hefei Tokamak-7</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Asif, M.; Gao, X.; Li, J. A new set of actively cooled toroidal double-ring graphite limiters has been developed in the Hefei Tokamak-7 (HT-7) [X. Gao et al., Phys. Plasmas 7, 2933 (2000)] for long pulse operation. The extension of operational region and density behavior with graphite (C) limiters have been studied in this paper. Extended high-density region at the high plasma current low-q{sub a} was obtained. The density profile with the C limiter was studied to compare with the previous molybdenum (Mo) limiter. The critical density of multifaceted asymmetric radiation from the edge (MARFE) onset is observed in the region of Z{sub eff}{sup 1/2}f{sub GW}=0.9{approx}1.2,more » where f{sub GW}=n{sub e}/n{sub GW}. (Here n{sub e} is the maximum line average electron density and n{sub GW} is the Greenwald density.) Under the same injected power, the critical density of MARFE onset with the new C limiter is much higher than the previous Mo limiter.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014PhRvL.112i5001K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014PhRvL.112i5001K">Efficient Neutron Production from a Novel Configuration of Deuterium Gas-Puff Z-Pinch</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Klir, D.; Kubes, P.; Rezac, K.; Cikhardt, J.; Kravarik, J.; Sila, O.; Shishlov, A. V.; Kovalchuk, B. M.; Ratakhin, N. A.; Kokshenev, V. A.; Labetsky, A. Yu.; Cherdizov, R. K.; Fursov, F. I.; Kurmaev, N. E.; Dudkin, G. N.; Nechaev, B. A.; Padalko, V. N.; Orcikova, H.; Turek, K. 2014-03-01 A novel configuration of a deuterium z pinch has been used to generate fusion neutrons. Injecting an outer hollow cylindrical plasma shell around an inner deuterium gas puff, neutron yields from DD reactions reached Yn=(2.9±0.3)×1012 at 700 ns implosion time and 2.7 MA current. Such a neutron yield means a tenfold increase in comparison with previous deuterium gas puff experiments at the same current generator. The increase of beam-target yields was obtained by a larger amount of current assembled on the z-pinch axis, and subsequently by higher induced voltage and higher energies of deuterons. A stack of CR-39 track detectors on the z-pinch axis showed hydrogen ions up to 38 MeV. Maximum neutron energies of 15 and 22 MeV were observed by radial and axial time-of-flight detectors, respectively. The number of DD neutrons per one joule of stored plasma energy approached 5×107. This implies that deuterium gas puff z pinches belong to the most efficient plasma-based sources of DD neutrons. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017PPCF...59e4007T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017PPCF...59e4007T">Enhancement of axial momentum lost to the radial wall by the upstream magnetic field in a helicon source</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Takahashi, Kazunori; Ando, Akira 2017-05-01 Individual measurements of forces exerted to an upstream back wall, a radial source wall, and a magnetic field of a helicon plasma thruster, which has two solenoids upstream and downstream of a radiofrequency antenna, are precisely measured. Two different structures of magnetic field lines in the source are tested, where the solenoid current is supplied to either only the downstream solenoid or to both the solenoids. It is observed that the high density plasma exists upstream of the rf antenna when both the solenoids are powered, while the maximum density exists near the rf antenna when only the downstream solenoid is powered. Although the force exerted to the back wall is increased for the two solenoids case, the axial momentum lost to the radial wall is simultaneously enhanced; then the total force exerted to the whole structure of the thruster is found to be very similar for the two magnetic field configurations. It is shown that the individual force measurement provides useful information on the plasma momentum interacting with the physical boundaries and the magnetic fields. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2004SPIE.5448..602B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2004SPIE.5448..602B">Femtosecond ablation applied to deep-drilling of hard metals</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Bruneau, Sebastien; Hermann, Joerg; Dumitru, Gabriel; Sentis, Marc L. 2004-09-01 Mechanisms responsible for the limitation of the aspect ratio obtained by deep drilling of hard metals are investigated in the present work. Cemented carbide targets have been irradiated with laser pulses of 100 fs duration and 100 μJ maximum energy delivered by a Ti:sapphire laser system. The experiments are carried out in different gas environments (vacuum, air, helium up to atmospheric pressure) with incident laser fluences ranging from 1 to 20 Jcm-2. During deep drilling, the laser-induced ablation plume is characterized by means of in-situ plasma diagnostics. Fast imaging is used to observe the expansion behavior of the plasma plume whereas time- and space-resolved emission spectroscopy is employed to analyze the plasma composition. After irradiation, the laser-produced craters were examined by optical microscopy. A correlation between the ablation plume characteristics and the morphological changes of the mciro-holes is established. The results indicate that nanoclusters, that present a significant part of the ablated material, are responsbile for the alteration of the crater shape in the high laser fluence regime. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/20020059586','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20020059586">Etching of Silicon in HBr Plasmas for High Aspect Ratio Features</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Hwang, Helen H.; Meyyappan, M.; Mathad, G. S.; Ranade, R. 2002-01-01 Etching in semiconductor processing typically involves using halides because of the relatively fast rates. Bromine containing plasmas can generate high aspect ratio trenches, desirable for DRAM and MEMS applications, with relatively straight sidewalk We present scanning electron microscope images for silicon-etched trenches in a HBr plasma. Using a feature profile simulation, we show that the removal yield parameter, or number of neutrals removed per incident ion due to all processes (sputtering, spontaneous desorption, etc.), dictates the profile shape. We find that the profile becomes pinched off when the removal yield is a constant, with a maximum aspect ratio (AR) of about 5 to 1 (depth to height). When the removal yield decreases with increasing ion angle, the etch rate increases at the comers and the trench bottom broadens. The profiles have ARs of over 9:1 for yields that vary with ion angle. To match the experimentally observed etched time of 250 s for an AR of 9:1 with a trench width of 0.135 microns, we find that the neutral flux must be 3.336 x 10(exp 17)sq cm/s. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1463317','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1463317">Comparison between the effects of inhaled isoprenaline and fenoterol on plasma cyclic AMP and heart rate in normal subjects.</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Fairfax, A J; Rehahn, M; Jones, D; O'Malley, B 1984-01-01 The time course of changes in plasma cyclic AMP, heart rate and bronchial tone after inhalation of fenoterol or isoprenaline from a dose-metered aerosol are reported in a group of normal subjects. After isoprenaline, plasma cyclic AMP increased rapidly reaching a peak by 10 min and returned to basal levels within 60 min. A rapid, transient rise in heart rate occurred that was maximal by 5 min and returned to a basal level by 45 min. After fenoterol, the changes in cyclic AMP and heart rate were of much longer duration. The rise in plasma cyclic AMP was slower in onset and of greater magnitude than for isoprenaline, reaching a peak by 20 min and remaining above basal level for more than 6 h. The maximum increase in heart rate after fenoterol was less than that observed with isoprenaline but an elevated rate persisted for 4 h after inhalation of fenoterol. Fenoterol is known to have a longer duration of action as a bronchodilator in comparison with isoprenaline. The prolonged rise in plasma cyclic AMP in normal subjects given inhaled fenoterol may reflect this long duration of action. The concomitant rise in heart rate, however, suggests that the duration of plasma cyclic AMP response may in part be due to the systemic effect of the fraction of inhaled fenoterol known to be absorbed via the buccal and intestinal routes. PMID:6322828 </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li class="active">16</li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_17" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li class="active">17</li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="321"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/464357','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/464357">Serum and urine inorganic fluoride concentrations and urine oxalate concentrations following methoxyflurane anesthesia in the dog.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Brunson, D B; Stowe, C M; McGrath, C J 1979-02-01 Plasma fluoride, urine fluoride and urine oxalate concentrations were measured before administering an anesthetic to 8 dogs, and at 0, 3, 9, 24, 48, and 72 hours following 1.5 hours of anesthesia with 1% methoxyflurane. Plasma and urine osmolalities were measured and compared with fluoride and oxalate values. Fluoride concentration increased in both plasma and urine following anesthesia when compared with the preanesthetic concentrations. Maximum mean plasma inorganic fluoride was 106.71 mumoles per liter (+/- 25.44 SE) at 9 hours after exposure to methoxyflurane was completed. By 72 hours after exposure to methoxyflurane the plasma fluoride concentration was 23.47 microM/L (+/- 5.74 SE). Mean urine inorganic fluoride concentration was highest at 9 hours after exposure to methoxyflurane and reached 6047.03 microM/L (+/- 1378.46 SE) as compared to the mean preanesthetic base-line concentration of 542.68 microM/L (+/- 132.93 SE), and the 72 hour mean urine fluoride concentration which was 1593.78 microM/L (+/- 579.46 SE). Urine oxalate concentrations, when compared with urine osmolality (mg/mOsm), increased throughout the study. The 72-hour concentration after exposure to methoxyflurane was 2.5 times the preanesthetic (mg/mOsm) oxalate concentration. Plasma osmolality did not change markedly during the study. Urine osmolalities varied between animals and collection times, but a consistent pattern did not occur. Clinical and laboratory signs of renal dysfunction were not observed in any animal during the study. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19930065428&hterms=1605&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3D%2526%25231605','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19930065428&hterms=1605&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3D%2526%25231605">High latitude field aligned light ion flows in the topside ionosphere deduced from ion composition and plasma temperatures</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Grebowsky, J. M.; Hoegy, W. R.; Chen, T. C. 1993-01-01 Using a comprehensive ionospheric data set comprised of all available ion composition and plasma temperature measurements from satellites, the vertical distributions of ion composition and plasma temperatures are defined from middle latitudes up into the polar cap for summer conditions for altitudes below about 1200 km. These data are sufficient to allow a numerical estimation of the latitudinal variation of the light ion outflows from within the plasmasphere to the polar wind regions. The altitude at which significant light ion outflow begins is found to be lower during solar minimum conditions than during solar maximum. The H(+) outward speeds are of the order of 1 km/s near 1100 km during solar maximum but attain several km/s speeds for solar minimum. He(+) shows a similar altitude development of flow but attains polar cap speeds much less than 1 km/s at altitudes below 1100 km, particularly under solar maximum conditions. Outward flows are also found in the topside F-region for noontime magnetic flux tubes within the plasmasphere. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018RScI...89e3108S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018RScI...89e3108S">Novel plasma source for safe beryllium spectral line studies in the presence of beryllium dust</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Stankov, B. D.; Vinić, M.; Gavrilović Božović, M. R.; Ivković, M. 2018-05-01 Plasma source for beryllium spectral line studies in the presence of beryllium dust particles was realised. The guideline during construction was to prevent exposure to formed dust, considering the toxicity of beryllium. Plasma source characterization through determination of optimal working conditions is described. The necessary conditions for Be spectral line appearance and optimal conditions for line shape measurements are found. It is proven experimentally that under these conditions dust appears coincidently with the second current maximum. The electron density measured after discharge current maximum is determined from the peak separation of the hydrogen Balmer beta spectral line, and the electron temperature is determined from the ratios of the relative intensities of Be spectral lines emitted from successive ionized stages of atoms. Maximum values of electron density and temperature are measured to be 9.3 × 1022 m-3 and 16 800 K, respectively. Construction details and testing of the BeO discharge tube in comparison with SiO2 and Al2O3 discharge tubes are also presented in this paper. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/1423517-linear-feature-detection-algorithm-astronomical-surveys-ii-defocusing-effects-meteor-tracks','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/1423517-linear-feature-detection-algorithm-astronomical-surveys-ii-defocusing-effects-meteor-tracks">Linear feature detection algorithm for astronomical surveys – II. Defocusing effects on meteor tracks</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Bektešević, Dino; Vinković, Dejan; Rasmussen, Andrew Given the current limited knowledge of meteor plasma micro-physics and its interaction with the surrounding atmosphere and ionosphere, meteors are a highly interesting observational target for high-resolution wide-field astronomical surveys. Such surveys are capable of resolving the physical size of meteor plasma heads, but they produce large volumes of images that need to be automatically inspected for possible existence of long linear features produced by meteors. Here in this paper, we show how big aperture sky survey telescopes detect meteors as defocused tracks with a central brightness depression. We derive an analytic expression for a defocused point source meteor trackmore » and use it to calculate brightness profiles of meteors modelled as uniform brightness discs. We apply our modelling to meteor images as seen by the Sloan Digital Sky Survey and Large Synoptic Survey Telescope telescopes. The expression is validated by Monte Carlo ray-tracing simulations of photons travelling through the atmosphere and the Large Synoptic Survey Telescope telescope optics. We show that estimates of the meteor distance and size can be extracted from the measured full width at half-maximum and the strength of the central dip in the observed brightness profile. However, this extraction becomes difficult when the defocused meteor track is distorted by the atmospheric seeing or contaminated by a long-lasting glowing meteor trail. The full width at half-maximum of satellite tracks is distinctly narrower than meteor values, which enables removal of a possible confusion between satellites and meteors.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1423517-linear-feature-detection-algorithm-astronomical-surveys-ii-defocusing-effects-meteor-tracks','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1423517-linear-feature-detection-algorithm-astronomical-surveys-ii-defocusing-effects-meteor-tracks">Linear feature detection algorithm for astronomical surveys – II. Defocusing effects on meteor tracks</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a> Bektešević, Dino; Vinković, Dejan; Rasmussen, Andrew; ... 2017-12-05 Given the current limited knowledge of meteor plasma micro-physics and its interaction with the surrounding atmosphere and ionosphere, meteors are a highly interesting observational target for high-resolution wide-field astronomical surveys. Such surveys are capable of resolving the physical size of meteor plasma heads, but they produce large volumes of images that need to be automatically inspected for possible existence of long linear features produced by meteors. Here in this paper, we show how big aperture sky survey telescopes detect meteors as defocused tracks with a central brightness depression. We derive an analytic expression for a defocused point source meteor trackmore » and use it to calculate brightness profiles of meteors modelled as uniform brightness discs. We apply our modelling to meteor images as seen by the Sloan Digital Sky Survey and Large Synoptic Survey Telescope telescopes. The expression is validated by Monte Carlo ray-tracing simulations of photons travelling through the atmosphere and the Large Synoptic Survey Telescope telescope optics. We show that estimates of the meteor distance and size can be extracted from the measured full width at half-maximum and the strength of the central dip in the observed brightness profile. However, this extraction becomes difficult when the defocused meteor track is distorted by the atmospheric seeing or contaminated by a long-lasting glowing meteor trail. The full width at half-maximum of satellite tracks is distinctly narrower than meteor values, which enables removal of a possible confusion between satellites and meteors.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28417439','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28417439">Clinical Pharmacokinetics of Sacubitril/Valsartan (LCZ696): A Novel Angiotensin Receptor-Neprilysin Inhibitor.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Ayalasomayajula, Surya; Langenickel, Thomas; Pal, Parasar; Boggarapu, Sreedevi; Sunkara, Gangadhar 2017-12-01 Sacubitril/valsartan (LCZ696) is indicated for the treatment of heart failure with reduced ejection fraction. Absorption of sacubitril/valsartan and conversion of sacubitril (prodrug) to sacubitrilat (neprilysin inhibitor) was rapid with maximum plasma concentrations of sacubitril, sacubitrilat, and valsartan (angiotensin receptor blocker) reaching within 0.5, 1.5-2.0, and 2.0-3.0 h, respectively. With a two-fold increase in dose, an increase in the area under the plasma concentration-time curve was proportional for sacubitril, ~1.9-fold for sacubitrilat, and ~1.7-fold for valsartan in healthy subjects. Following multiple twice-daily administration, steady-state maximum plasma concentration was reached within 3 days, showing no accumulation for sacubitril and valsartan, while ~1.6-fold accumulation for sacubitrilat. Sacubitril is eliminated predominantly as sacubitrilat through the kidney; valsartan is eliminated mainly by biliary route. Drug-drug interactions of sacubitril/valsartan were evaluated with medications commonly used in patients with heart failure including furosemide, warfarin, digoxin, carvedilol, levonorgestrel/ethinyl estradiol combination, amlodipine, omeprazole, hydrochlorothiazide, intravenous nitrates, metformin, statins, and sildenafil. Co-administration with sacubitril/valsartan increased the maximum plasma concentration (~2.0-fold) and area under the plasma concentration-time curve (1.3-fold) of atorvastatin; however, it did not affect the pharmacokinetics of simvastatin. Age, sex, or ethnicity did not affect the pharmacokinetics of sacubitril/valsartan. In patients with heart failure vs. healthy subjects, area under the plasma concentration-time curves of sacubitril, sacubitrilat, and valsartan were higher by approximately 1.6-, 2.1-, and 2.3-fold, respectively. Renal impairment had no significant impact on sacubitril and valsartan area under the plasma concentration-time curves, while the area under the plasma concentration-time curve of sacubitrilat correlated with degree of renal function (1.3-, 2.3-, 2.9-, and 3.3-fold with mild, moderate, and severe renal impairment, and end-stage renal disease, respectively). Moderate hepatic impairment increased the area under the plasma concentration-time curves of valsartan and sacubitrilat ~2.1-fold. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28527109','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28527109">Erratum to: Clinical Pharmacokinetics of Sacubitril/Valsartan (LCZ696): A Novel Angiotensin Receptor-Neprilysin Inhibitor.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Ayalasomayajula, Surya; Langenickel, Thomas; Pal, Parasar; Boggarapu, Sreedevi; Sunkara, Gangadhar 2018-01-01 Sacubitril/valsartan (LCZ696) is indicated for the treatment of heart failure with reduced ejection fraction. Absorption of sacubitril/valsartan and conversion of sacubitril (prodrug) to sacubitrilat (neprilysin inhibitor) was rapid with maximum plasma concentrations of sacubitril, sacubitrilat, and valsartan (angiotensin receptor blocker) reaching within 0.5, 1.5-2.0, and 2.0-3.0 h, respectively. With a twofold increase in dose, an increase in the area under the plasma concentration-time curve was proportional for sacubitril, ~1.9-fold for sacubitrilat, and ~1.7-fold for valsartan in healthy subjects. Following multiple twice-daily administration, steady-state maximum plasma concentration was reached within 3 days, showing no accumulation for sacubitril and valsartan, while ~1.6-fold accumulation for sacubitrilat. Sacubitril is eliminated predominantly as sacubitrilat through the kidney; valsartan is eliminated mainly by biliary route. Drug-drug interactions of sacubitril/valsartan were evaluated with medications commonly used in patients with heart failure including furosemide, warfarin, digoxin, carvedilol, levonorgestrel/ethinyl estradiol combination, amlodipine, omeprazole, hydrochlorothiazide, intravenous nitrates, metformin, statins, and sildenafil. Co-administration with sacubitril/valsartan increased the maximum plasma concentration (~2.0-fold) and area under the plasma concentration-time curve (1.3-fold) of atorvastatin; however, it did not affect the pharmacokinetics of simvastatin. Age, sex, or ethnicity did not affect the pharmacokinetics of sacubitril/valsartan. In patients with heart failure vs. healthy subjects, area under the plasma concentration-time curves of sacubitril, sacubitrilat, and valsartan were higher by approximately 1.6-, 2.1-, and 2.3-fold, respectively. Renal impairment had no significant impact on sacubitril and valsartan area under the plasma concentration-time curves, while the area under the plasma concentration-time curve of sacubitrilat correlated with degree of renal function (1.3-, 2.3-, 2.9-, and 3.3-fold with mild, moderate, and severe renal impairment, and end-stage renal disease, respectively). Moderate hepatic impairment increased the area under the plasma concentration-time curves of valsartan and sacubitrilat ~2.1-fold. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017PPCF...59a4049S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017PPCF...59a4049S">Experimental studies of high-confinement mode plasma response to non-axisymmetric magnetic perturbations in ASDEX Upgrade</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Suttrop, W.; Kirk, A.; Nazikian, R.; Leuthold, N.; Strumberger, E.; Willensdorfer, M.; Cavedon, M.; Dunne, M.; Fischer, R.; Fietz, S.; Fuchs, J. C.; Liu, Y. Q.; McDermott, R. M.; Orain, F.; Ryan, D. A.; Viezzer, E.; The ASDEX Upgrade Team; The DIII-D Team; The Eurofusion MST1 Team 2017-01-01 The interaction of externally applied small non-axisymmetric magnetic perturbations (MP) with tokamak high-confinement mode (H-mode) plasmas is reviewed and illustrated by recent experiments in ASDEX Upgrade. The plasma response to the vacuum MP field is amplified by stable ideal kink modes with low toroidal mode number n driven by the H-mode edge pressure gradient (and associated bootstrap current) which is experimentally evidenced by an observable shift of the poloidal mode number m away from field alignment (m = qn, with q being the safety factor) at the response maximum. A torque scan experiment demonstrates the importance of the perpendicular electron flow for shielding of the resonant magnetic perturbation, as expected from a two-fluid MHD picture. Two significant effects of MP occur in H-mode plasmas at low pedestal collisionality, ν \\text{ped}\\ast≤slant 0.4 : (a) a reduction of the global plasma density by up to 61 % and (b) a reduction of the energy loss associated with edge localised modes (ELMs) by a factor of up to 9. A comprehensive database of ELM mitigation pulses at low {ν\\ast} in ASDEX Upgrade shows that the degree of ELM mitigation correlates with the reduction of pedestal pressure which in turn is limited and defined by the onset of ELMs, i. e. a modification of the ELM stability limit by the magnetic perturbation. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2002cosp...34E.460K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2002cosp...34E.460K">Nonlinear dynamic processes in modified ionospheric plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kochetov, A.; Terina, G. Presented work is a contribution to the experimental and theoretical study of nonlinear effects arising on ionospheric plasma under the action of powerful radio emission (G.I. Terina, J. Atm. Terr. Phys., 1995, v.57, p.273; A.V. Kochetov et. al., Advances in Space Research, 2002, in press). The experimental results were obtained by the method of sounding of artificially disturbed ionosphere by short radio pulses. The amplitude and phase characteristics of scattered signal as of "caviton" type (CS) (analogy of narrow-band component of stimulation electromagnetic emission (SEE)) as the main signal (MS) of probing transmitter are considered. The theoretical model is based on numerical solution of driven nonlinear Shrödinger equation (NSE) in inhomogeneous plasma. The simulation allows us to study a self-consistent spatial-temporal dynamics of field and plasma. The observed evolution of phase characteristics of MS and CS qualitatively correspond to the results of numerical simulation and demonstrate the penetration processes of powerful electromagnetic wave in supercritical (in linear approach) plasma regions. The modeling results explain also the periodic generation of CS, the travel CS maximum down to density gradient, the aftereffect of CS. The obtained results show the excitation of strong turbulence and allow us to interpret CS, NC and so far inexplicable phenomena as "spikes" too. The work was supported in part by Russian Foundation for Basic Research (grants Nos. 99-02-16642, 99-02- 16399). </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29909979','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29909979">Effect of storage duration on cytokine stability in human serum and plasma.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Vincent, Fabien B; Nim, Hieu T; Lee, Jacinta P W; Morand, Eric F; Harris, James 2018-06-14 Quantification of analytes such as cytokines in serum samples is intrinsic to translational research in immune diseases. Optimising pre-analytical conditions is critical for ensuring study quality, including evaluation of cytokine stability. We aimed to evaluate the effect on cytokine stability of storage duration prior to freezing of serum, and compare to plasma samples obtained from patients with systemic lupus erythematosus (SLE). Protein stability was analysed by simultaneously quantifying 18 analytes using a custom multi-analyte profile in SLE patient serum and plasma samples that had been prospectively stored at 4 °C for pre-determined periods between 0 and 30 days, prior to freezing. Six analytes were excluded from analysis, because most tested samples were above or below the limit of detection. Amongst the 12 analysed proteins, 11 did not show significant signal degradation. Significant signal degradation was observed from the fourth day of storage for a single analyte, CCL19. Proteins levels were more stable in unseparated serum compared to plasma for most analytes, with the exception of IL-37 which appears slightly more stable in plasma. Based on this, a maximum 3 days of storage at 4 °C for unseparated serum samples is recommended for biobanked samples intended for cytokine analysis in studies of human immune disease. Copyright © 2018 Elsevier Ltd. All rights reserved. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012RScI...83j4705Z','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012RScI...83j4705Z">Plasma-filled diode based on the coaxial gun</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Zherlitsyn, A. A.; Kovalchuk, B. M.; Pedin, N. N. 2012-10-01 The paper presents the results of studies of a coaxial gun for a plasma-filled electron diode. Effects of the discharge channel diameter and gun current on characteristics of the plasma and pulse generated in the diode were investigated. The electron beam with maximum energy of ≥1 MeV at the current of ≈100 kA was obtained in the experiments with a plasma-filled diode. The energy of ≈5 kJ with the peak power of ≥100 GW dissipated in the diode. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23126788','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23126788">Plasma-filled diode based on the coaxial gun.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Zherlitsyn, A A; Kovalchuk, B M; Pedin, N N 2012-10-01 The paper presents the results of studies of a coaxial gun for a plasma-filled electron diode. Effects of the discharge channel diameter and gun current on characteristics of the plasma and pulse generated in the diode were investigated. The electron beam with maximum energy of ≥1 MeV at the current of ≈100 kA was obtained in the experiments with a plasma-filled diode. The energy of ≈5 kJ with the peak power of ≥100 GW dissipated in the diode. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017SoPh..292...50R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017SoPh..292...50R">New Results from the Solar Maximum Mission/Bent Crystal Spectrometer</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Rapley, C. G.; Sylwester, J.; Phillips, K. J. H. 2017-04-01 The Bent Crystal Spectrometer (BCS) onboard the NASA Solar Maximum Mission was part of the X-ray Polychromator, which observed numerous flares and bright active regions from February to November 1980, when operation was suspended as a result of the failure of the spacecraft fine-pointing system. Observations resumed following the Space Shuttle SMM Repair Mission in April 1984 and continued until November 1989. BCS spectra have been widely used in the past to obtain temperatures, emission measures, and turbulent and bulk flows during flares, as well as element abundances. Instrumental details including calibration factors not previously published are given here, and the in-orbit performance of the BCS is evaluated. Some significant changes during the mission are described, and recommendations for future instrumentation are made. Using improved estimates for the instrument parameters and operational limits, it is now possible to obtain de-convolved calibrated spectra that show finer detail than before, providing the means for improved interpretation of the physics of the emitting plasmas. The results indicate how historical archived data can be re-used to obtain enhanced and new, scientifically valuable results. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013PlPhR..39.1035M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013PlPhR..39.1035M">Optical characteristics and parameters of gas-discharge plasma in a mixture of mercury dibromide vapor with neon</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Malinina, A. A.; Malinin, A. N. 2013-12-01 Results are presented from studies of the optical characteristics and parameters of plasma of a dielectric barrier discharge in a mixture of mercury dibromide vapor with neon—the working medium of a non-coaxial exciplex gas-discharge emitter. The electron energy distribution function, the transport characteristics, the specific power losses for electron processes, the electron density and temperature, and the rate constants for the processes of elastic and inelastic electron scattering by the working mixture components are determined as functions of the reduced electric field. The rate constant of the process leading to the formation of exciplex mercury monobromide molecules is found to be 1.6 × 10-14 m3/s for a reduced electric field of E/ N = 15 Td, at which the maximum emission intensity in the blue-green spectral region (λmax = 502 nm) was observed in this experiment. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JMEP...27..997K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JMEP...27..997K">Al2O3-TiC Composite Prepared by Spark Plasma Sintering Process: Evaluation of Mechanical and Tribological Properties</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kumar, Rohit; Chaubey, A. K.; Bathula, Sivaiah; Prashanth, K. G.; Dhar, Ajay 2018-03-01 Al2O3-10TiC composites were synthesized by spark plasma sintering (SPS) process. Microstructural and mechanical properties of the composite reveal homogeneous distribution of the fine TiC particles in the matrix. The samples were produced with different sintering temperature, and it shows that the hardness and density gradually increases with increasing sintering temperature. Abrasion wear test result reveals that the composite sintered at 1500 °C shows high abrasion resistance (wt. loss 0.016 g) and the lowest abrasion resistance was observed for the composite sample sintered at 1100 °C (wt. loss 1.459 g). The profilometry surface roughness study shows that sample sintered at 1100 °C shows maximum roughness ( R a = 6.53 µm) compared to the sample sintered at 1500 °C ( R a = 0.66 µm) corroborating the abrasion wear test results. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2000ApPhL..77.1020V','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2000ApPhL..77.1020V">Magnetoresistance enhancement in specular, bottom-pinned, Mn83Ir17 spin valves with nano-oxide layers</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Veloso, A.; Freitas, P. P.; Wei, P.; Barradas, N. P.; Soares, J. C.; Almeida, B.; Sousa, J. B. 2000-08-01 Bottom-pinned Mn83Ir17 spin valves with enhanced specular scattering were fabricated, showing magnetoresistance (MR) values up to 13.6%, lower sheet resistance R□ and higher ΔR□. Two nano-oxide layers (NOL) are grown on both sides of the CoFe/Cu/CoFe spin valve structure by natural oxidation or remote plasma oxidation of the starting CoFe layer. Maximum MR enhancement is obtained after just 1 min plasma oxidation. Rutherford backscattering analysis shows that a 15±2 Å oxide layer grows at the expense of the initial (prior to oxidation) CoFe layer, with ˜12% reduction of the initial 40 Å CoFe thickness. X-ray reflectometry indicates that Kiessig fringes become better defined after NOL growth, indicating smoother inner interfaces, in agreement with the observed decrease of the spin valve ferromagnetic Néel coupling. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009APS..DPPPP8086S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009APS..DPPPP8086S">Non-solenoidal startup and low-β operations in Pegasus</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Schlossberg, D. J.; Battaglia, D. J.; Bongard, M. W.; Fonck, R. J.; Redd, A. J. 2009-11-01 Non-solenoidal startup using point-source DC helicity injectors (plasma guns) has been achieved in the Pegasus Toroidal Experiment for plasmas with Ip in excess of 100 kA using Iinj<4,A. The maximum achieved Ip tentatively scales as √ITFIinj/w, where w is the radial thickness of the gun-driven edge. The Ip limits appear to conform to a simple stationary model involving helicity conservation and Taylor relaxation. However, observed MHD activity reveals the additional dynamics of the relaxation process, evidenced by intermittent bursts of n=1 activity correlated with rapid redistribution of the current channel. Recent upgrades to the gun system provide higher helicity injection rates, smaller w, a more constrained gun current path, and more precise diagnostics. Experimental goals include extending parametric scaling studies, determining the conditions where parallel conduction losses dominate the helicity dissipation, and building the physics understanding of helicity injection to confidently design gun systems for larger, future tokamaks. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017APS..DPPY11042G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017APS..DPPY11042G">Stochastic acceleration of electrons from multiple uncorrelated plasma waves</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Gee, David; Michel, Pierre; Wurtele, Jonathan 2017-10-01 One-dimensional theory puts a strict limit on the maximum energy attainable by an electron trapped and accelerated by an electron plasma wave (EPW). However, experimental measurements of hot electron distributions accelerated by stimulated Raman scattering (SRS) in ICF experiments typically show a thermal distribution with temperatures of the order of the kinetic energy of the resonant EPW's (Thot mvp2 , where vp is the phase velocity of the EPW's driven by SRS) and no clear cutoff at high energies. In this project, we are investigating conditions under which electrons can be stochastically accelerated by multiple uncorrelated EPW's, such as those generated by incoherent laser speckles in large laser spots like the ones used on NIF ( mm-size), and reproduce distributions similar to those observed in experiments. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract No. DE-AC52-07NA27344. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29331926','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29331926">Two hump-shaped angular distributions of neutrons and soft X-rays in a small plasma focus device.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Habibi, Morteza 2018-03-01 Angular distributions of soft X-rays (SXRs) and neutrons emitted by a small plasma focus device (PFD) were investigated simultaneously using TLD-100 dosimeters and Geiger-Muller activation counters, respectively. The distributions represented two humps with a small dip at the angular position 0° and reduced from the angles of ± 15° and ± 30° for the neutrons and SXRs, respectively. The maximum yield of 2.98 × 10 8 neutrons per shot of the device was obtained at 13.5kV and 6.5mbar. A time of flight (TOF) of 75.2ns between the hard X-ray and the neutron peaks corresponds to neutrons with energy of 2.67MeV. A similar behavior was observed between the angular distributions of neutron and soft X-ray emissions. Copyright © 2018 Elsevier Ltd. All rights reserved. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27591283','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27591283">Feed contamination with Fusarium mycotoxins induces a corticosterone stress response in broiler chickens.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Antonissen, G; De Baere, S; Devreese, M; Van Immerseel, F; Martel, A; Croubels, S 2017-01-01 The aim of the present study was to evaluate the effect of the Fusarium mycotoxins deoxynivalenol (DON) and fumonisins (FBs) on the stress response in broiler chickens, using corticosterone (CORT) in plasma as a biomarker. Chickens were fed either a control diet, a DON contaminated diet, a FBs contaminated diet, or a DON and FBs contaminated diet for 15 d at concentrations close to the European Union maximum guidance levels for DON and FBs in poultry. Mean plasma CORT levels were significantly higher in broiler chickens fed a DON contaminated and a DON and FBs contaminated diet compared to birds fed a control diet. A similar trend was observed for animals fed a FBs contaminated diet. Consequently, feeding broilers a diet contaminated with DON and/or FBs induced a CORT stress response, which may indicate a negative effect on animal welfare. © 2016 Poultry Science Association Inc. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li class="active">17</li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_18" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li class="active">18</li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="341"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/1897274','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/1897274">Postprandial plasma D-lactate concentrations after yogurt ingestion.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> de Vrese, M; Barth, C A 1991-06-01 The risk of D-lactic acidosis after consumption of yogurt was investigated in seven healthy volunteers. After ingestion of yogurt containing 1.06 mmol/kg body weight, D-lactic acid postprandial plasma D-lactate concentrations increased from 0.070 +/- 0.020 to a maximum of 0.200 +/- 0.010 mmol/l within 60 min. That was half the maximum concentration after the equivalent amount of D-lactate in the form of an aqueous solution of DL-lactate. The shape of the postprandial plasma D-lactate peak was flatter, but much broader after yogurt than after the aqueous solution, the peak areas being equal. When 0.64 mmol/kg body weight D-lactate were consumed as yogurt, plasma concentrations amounted to 0.086 +/- 0.030 mmol/l. Signs of a mild, transient, compensated metabolic acidosis, which was apparent in case of the aqueous lactic acid solution did not occur in case of yogurt. It is concluded that the consumption of foods containing D-lactic acid gives no reason for concern in healthy adults. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27891624','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27891624">Quarantine versus pathogen-reduced plasma-coagulation factor content and rotational thromboelastometry coagulation.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Theusinger, Oliver M; Goslings, David; Studt, Jan-Dirk; Brand-Staufer, Brigitte; Seifert, Burkhardt; Spahn, Donat R; Frey, Beat M 2017-03-01 Different types of fresh-frozen plasma (FFP) exist, and the concentrations of plasma proteins vary between individuals and blood groups. Furthermore, processing may also influence the content. Quarantine-stored plasma (qFFP) and plasma that was pathogen-reduced using blood-safety (Intercept) technology (piFFP) were analyzed regarding procoagulant and anticoagulant hemostasis proteins, including endogenous thrombin (thrombin-generation) potential (ETP). Thirty-five samples of each type of FFP were analyzed using only male Blood Group O donors. FFP units were stored frozen for comparable periods of time before plasma protein content was assessed. Once the units were thawed, all tests were completed within 4 hours. The results are presented as means ± standard deviations or as median (minimum; maximum) and were compared using independent-sample t tests (significance, p < 0.01). Significantly higher concentrations of adintegrin-like and metalloprotease with thrombospondin type-13 motifs (ADAMTS13), fibrinogen, Factor (F)V, FVIII, FXIII, protein S, protein S activity, antithrombin, microvesicle (<900 nm), and α2 antiplasmin were observed in qFFP. The variability of factors was significantly lower in piFFP. Tissue factor (TF) at 1 picomolar (pM) exhibited significantly longer lag time, a lower peak, lower ETP, and a lower velocity index in qFFP compared with piFFP. In TF at 5 pM, significant differences in lag time (longer in qFFP), velocity index (lower in qFFP), and peak (lower in qFFP) were observed. Rotational thromboelastometry revealed a significantly longer (p = 0.002) clot-formation time with intrinsic thromboelastometry for piFFP and a significantly shorter clotting time (p = 0.004) with thromboelastometry fibrinogen testing for piFFP. Pathogen reduction reduces procoagulant and anticoagulant coagulation factors as well as variability. A thrombin-generation assay showed no reduced ETP and no supraphysiological thrombin generation. None of the FFP preparations is likely to be effective for treating fibrinogen deficiency. © 2016 AABB. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JPhD...50O5205Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JPhD...50O5205Y">Gas flow rate dependence of the discharge characteristics of a helium atmospheric pressure plasma jet interacting with a substrate</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Yan, Wen; Economou, Demetre J. 2017-10-01 A 2D (axisymmetric) computational study of the discharge characteristics of an atmospheric pressure plasma jet as a function of gas flow rate was performed. The helium jet emerged from a dielectric tube, with an average gas flow velocity in the range 2.5-20 m s-1 (1 atm, 300 K) in a nitrogen ambient, and impinged on a substrate a short distance dowstream. The effect of the substrate conductivity (conductror versus insulator) was also studied. Whenever possible, simulation predictions were compared with published experimental observations. Discharge ignition and propagation in the dielectric tube were hardly affected by the He gas flow velocity. Most properties of the plasma jet, however, depended sensitively on the He gas flow velocity, which determined the concentration distributions of helium and nitrogen in the mixing layer forming in the gap between the tube exit and the substrate. At low gas flow velocity, the plasma jet evolved from a hollow (donut-shaped) feature to one where the maximum of electron density was on axis. When the gas flow velocity was high, the plasma jet maintained its hollow structure until it struck the substrate. For a conductive substrate, the radial ion fluxes to the surface were relatively uniform over a radius of ~0.4-0.8 mm, and the dominant ion flux was that of He+. For a dielectric substrate, the radial ion fluxes to the surface peaked on the symmetry axis at low He gas flow velocity, but a hollow ion flux distribution was observed at high gas flow velocity. At the same time, the main ion flux switched from N2+ to He2+ as the He gas flow velocity increased from a low to a high value. The diameter of the plasma ‘footprint’ on the substrate first increased with increasing He gas flow velocity, and eventually saturated with further increases in velocity. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1198530','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1198530">Precursor–product relationship between intrahepatic albumin and plasma albumin</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> LeBouton, A. V. 1968-01-01 Rats were injected with [3H]leucine, and at various times thereafter labelled albumin was isolated by electrophoresis from their livers and blood plasma. The specific radioactivity of each protein was determined by spectrophotometry and liquid-scintillation spectrometry. Intrahepatic albumin was shown to be identical with plasma albumin by its electrophoretic mobility and antigenicity. It was found that intrahepatic albumin was the direct precursor of plasma albumin. Comparison of their specific radioactivities showed that intrahepatic albumin attained a higher specific radioactivity before plasma albumin. When plasma albumin reached its maximum specific radioactivity, that of intrahepatic albumin had decreased to a similar value. Thereafter, the specific radioactivity of intrahepatic albumin remained lower than that of plasma albumin. PMID:4966084 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2014413','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2014413">Steady-state pharmacokinetics of (R)- and (S)-methadone in methadone maintenance patients</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Foster, David J R; Somogyi, Andrew A; Dyer, Kyle R; White, Jason M; Bochner, Felix 2000-01-01 Aims To investigate the steady-state pharmacokinetics of (R)- and (S)-methadone in a methadone maintenance population. Methods Eighteen patients recruited from a public methadone maintenance program underwent an interdosing interval pharmacokinetic study. Plasma and urine samples were collected and analysed for methadone and its major metabolite (EDDP) using stereoselective h.p.l.c. Methadone plasma protein binding was examined using ultrafiltration, and plasma α1-acid glycoprotein concentrations were quantified by radial immunoassay. Results (R)-methadone had a significantly (P < 0.05) greater unbound fraction (mean 173%) and total renal clearance (182%) compared with (S)-methadone, while maximum measured plasma concentrations (83%) and apparent partial clearance of methadone to EDDP (76%) were significantly (P < 0.001) lower. When protein binding was considered (R)-methadone plasma clearance of the unbound fraction (59%) and apparent partial intrinsic clearance to EDDP (44%) were significantly (P < 0.01) lower than for (S)-methadone, while AUCτSS, (167%) was significantly (P < 0.001) greater. There were no significant (P > 0.2) differences between the methadone enantiomers for AUCτSS, steady-state plasma clearance, trough plasma concentrations and unbound renal clearance. Patients excreted significantly (P < 0.0001) more (R)-methadone and (S)-EDDP than the corresponding enantiomers. Considerable interindividual variability was observed for the pharmacokinetic parameters, with coefficients of variation of up to 70%. Conclusions Steady-state pharmacokinetics of unbound methadone are stereoselective, and there is large interindividual variability consistent with CYP3A4 mediated metabolism to the major metabolite EDDP; the variability did not obscure a significant dose-plasma concentration relationship. Stereoselective differences in the pharmacokinetics of methadone may have important implications for pharmacokinetic-pharmacodynamic modelling but is unlikely to be important for therapeutic drug monitoring of methadone, in the setting of opioid dependence. PMID:11069437 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JPhCS.774a2203T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JPhCS.774a2203T">Generator of chemically active low-temperature plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Tyuftyaev, A. S.; Gadzhiev, M. Kh; Sargsyan, M. A.; Demirov, N. A.; Spector, N. O. 2016-11-01 A new generator of high enthalpy (H 0 > 40 kJ/g), chemically active nitrogen and air plasmas was designed and constructed. Main feature of the generator is an expanding channel of an output electrode; the generator belongs to the class of DC plasma torches with thermionic cathode with an efficiency of 80%. The generator ensures the formation of a slightly divergent plasma jet (2α = 12°) with a diameter of D = 10-12 mm, an electric arc maximum power of 20-50 kW, plasma forming gas flow rate 1.0-2.0 g/s, and the average plasma temperature at an outlet of 8000-11000 K. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JGRA..122.1763M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JGRA..122.1763M">Jovian deep magnetotail composition and structure</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> McComas, D. J.; Allegrini, F.; Bagenal, F.; Ebert, R. W.; Elliott, H. A.; Nicolaou, G.; Szalay, J. R.; Valek, P.; Weidner, S. 2017-02-01 We analyze plasma ion observations from the Solar Wind Around Pluto instrument on New Horizons as it traveled back through the dusk flank of the Jovian magnetotail from 600 to more than 2500 Jovian radii behind the planet. We find that at all distances, light ions (mostly protons) dominate the heavy ions (S++ and O+) that are far more abundant in the near Jupiter plasma disk and that were expected to be the primary ions filling the Jovian magnetotail. This key new observation might indicate that heavy ions are confined closer to the equator than the spacecraft trajectory or a substantial addition of light ions via reconnection and/or mixing along the magnetopause boundary. However, because we find no evidence for acceleration of the tail plasma with distance, a more likely explanation seems to be that the heavy ions are preferentially released down the dawn flank of the magnetotail. Perhaps, this occurs as a part of the process where flux tubes, after expanding as they rotate across the near-tail region, need to pull back inward in order to fit within the dawnside of the magnetopause. A second major finding of this study is that there are two dominant periods of the plasma structures in the Jovian magnetotail: 3.53 (0.18 full width at half maximum (FWHM)) and 5.35 (0.38 FWHM) days. Remarkably, the first of these is identical within the errors to Europa's orbital period (3.55 days). Both of these results should provide important new fodder for Jovian magnetospheric theories and lead to a better understanding of Jupiter's magnetosphere. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29463072','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29463072">The Effects of Donepezil, an Acetylcholinesterase Inhibitor, on Impaired Learning and Memory in Rodents.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Shin, Chang Yell; Kim, Hae-Sun; Cha, Kwang-Ho; Won, Dong Han; Lee, Ji-Yun; Jang, Sun Woo; Sohn, Uy Dong 2018-05-01 A previous study in humans demonstrated the sustained inhibitory effects of donepezil on acetylcholinesterase (AChE) activity; however, the effective concentration of donepezil in humans and animals is unclear. This study aimed to characterize the effective concentration of donepezil on AChE inhibition and impaired learning and memory in rodents. A pharmacokinetic study of donepezil showed a mean peak plasma concentration of donepezil after oral treatment (3 and 10 mg/kg) of approximately 1.2 ± 0.4 h and 1.4 ± 0.5 h, respectively; absolute bioavailability was calculated as 3.6%. Further, AChE activity was inhibited by increasing plasma concentrations of donepezil, and a maximum inhibition of 31.5 ± 5.7% was observed after donepezil treatment in hairless rats. Plasma AChE activity was negatively correlated with plasma donepezil concentration. The pharmacological effects of donepezil are dependent upon its concentration and AChE activity; therefore, we assessed the effects of donepezil on learning and memory using a Y-maze in mice. Donepezil treatment (3 mg/kg) significantly prevented the progression of scopolamine-induced memory impairment in mice. As the concentration of donepezil in the brain increased, the recovery of spontaneous alternations also improved; maximal improvement was observed at 46.5 ± 3.5 ng/g in the brain. In conclusion, our findings suggest that the AChE inhibitory activity and pharmacological effects of donepezil can be predicted by the concentration of donepezil. Further, 46.5 ± 3.5 ng/g donepezil is an efficacious target concentration in the brain for treating learning and memory impairment in rodents. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012JPhCS.406a2028R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012JPhCS.406a2028R">The investigation of an electric arc in the long cylindrical channel of the powerful high-voltage AC plasma torch</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Rutberg, Ph G.; Popov, S. D.; Surov, A. V.; Serba, E. O.; Nakonechny, Gh V.; Spodobin, V. A.; Pavlov, A. V.; Surov, A. V. 2012-12-01 The comparison of conductivity obtained in experiments with calculated values is made in this paper. Powerful stationary plasma torches with prolonged period of continuous work are popular for modern plasmachemical applications. The maximum electrode lifetime with the minimum erosion can be reached while working on rather low currents. Meanwhile it is required to provide voltage arc drop for the high power achievement. Electric field strength in the arc column of the high-voltage plasma torch, using air as a plasma-forming gas, does not exceed 15 V/cm. It is possible to obtain the high voltage drop in the long arc stabilized in the channel by the intensive gas flow under given conditions. Models of high voltage plasma torches with rod electrodes with power up to 50 kW have been developed and investigated. The plasma torch arcs are burning in cylindrical channels. Present investigations are directed at studying the possibility of developing long arc plasma torches with higher power. The advantage of AC power supplies usage is the possibility of the loss minimization due to the reactive power compensation. The theoretical maximum of voltage arc drop for power supplies with inductive current limitations is about 50 % of the no-load voltage for a single-phase circuit and about 30 % for the three-phase circuit. Burning of intensively blown arcs in the long cylindrical channel using the AC power supply with 10 kV no-load voltage is experimentally investigated in the work. Voltage drops close to the maximum possible had been reached in the examined arcs in single-phase and three-phase modes. Operating parameters for single-phase mode were: current -30 A, voltage drop -5 kV, air flow rate 35 g/s; for three-phase mode: current (40-85) A, voltage drop (2.5-3.2) kV, air flow rate (60-100) g/s. Arc length in the installations exceeded 2 m. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1998emsh.rept.....T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1998emsh.rept.....T">Experimental Methods for Studying the Hessdalen-Phenomenon in the Light of the Proposed Theories: A Comparative Overview</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Teodorani, M.; Strand, E. Unexplained plasma-like atmospheric `light balls' are observed at very low altitudes during alternate phases of maximum and minimum in the Hessdalen area, located in central Norway. Several theories are presented in order to explain the observed phenomenon; among these: piezo-electricity from rocks, atmospheric ionization triggered by solar activity and cosmic rays. The presented study is aimed at proposing the use of a dedicated instrumental set-up, research experimental procedures and methods in order to prove or disprove every single theory: in this context several kinds of observational techniques, measurement strategies and physical tests of tactical relevance are discussed in detail. An introduction on any considered theory is presented together with a detailed discussion regarding the subsequent experimental phase. For each specific theory brief descriptions of the observable parameters and of the essential instrumental choices and a detailed discussion of measurement procedures coupled with suitable flow-charts, are presented. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20060045642&hterms=maxima&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D60%26Ntt%3Dmaxima','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20060045642&hterms=maxima&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D60%26Ntt%3Dmaxima">Dynamical Evolution of the Inner Heliosphere Approaching Solar Activity Maximum: Interpreting Ulysses Observations Using a Global MHD Model. Appendix 1</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Riley, Pete; Mikic, Z.; Linker, J. A. 2003-01-01 In this study we describe a series of MHD simulations covering the time period from 12 January 1999 to 19 September 2001 (Carrington Rotation 1945 to 1980). This interval coincided with: (1) the Sun s approach toward solar maximum; and (2) Ulysses second descent to the southern polar regions, rapid latitude scan, and arrival into the northern polar regions. We focus on the evolution of several key parameters during this time, including the photospheric magnetic field, the computed coronal hole boundaries, the computed velocity profile near the Sun, and the plasma and magnetic field parameters at the location of Ulysses. The model results provide a global context for interpreting the often complex in situ measurements. We also present a heuristic explanation of stream dynamics to describe the morphology of interaction regions at solar maximum and contrast it with the picture that resulted from Ulysses first orbit, which occurred during more quiescent solar conditions. The simulation results described here are available at: http://sun.saic.com. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20050131817&hterms=ATLAS&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D60%26Ntt%3DATLAS','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20050131817&hterms=ATLAS&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D60%26Ntt%3DATLAS">Spectral Atlas of X-ray Lines Emitted During Solar Flares Based on CHIANTI</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Landi, E.; Phillips, K. J. H. 2005-01-01 A spectral atlas of X-ray lines in the wavelength range 7.47-18.97 Angstroms is presented, based on high-resolution spectra obtained during two M-class solar flares (on 1980 August 25 and 1985 July 2) with the Flat Crystal Spectrometer on board the Solar Maximum Mission. The physical properties of the flaring plasmas are derived as a function of time using strong, isolated lines. From these properties predicted spectra using the CHIANTI database have been obtained which were then compared with wavelengths and fluxes of lines in the observed spectra to establish line identifications. identifications for nearly all the observed lines in the resulting atlas are given, with some significant corrections to previous analysis of these flare spectra. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1792788','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1792788">Paracetamol suppositories: a comparative study.</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Cullen, S; Kenny, D; Ward, O C; Sabra, K 1989-01-01 Paracetamol suppositories in two different bases were given to children who had fever after operations. Plasma concentrations and the effect on temperature were compared. There was a significant correlation between peak plasma concentrations and maximum drop in temperature. A lipophilic base produced better results than a hydrophilic base. PMID:2817936 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012APS..DPPTP8084D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012APS..DPPTP8084D">Initial Operation of the Miniaturized Inductively Heated Plasma Generator IPG6</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Dropmann, Michael; Herdrich, Georg; Laufer, Rene; Koch, Helmut; Gomringer, Chris; Cook, Mike; Schmoke, Jimmy; Matthews, Lorin; Hyde, Truell 2012-10-01 In close collaboration between the Center for Astrophysics, Space Physics and Engineering Research (CASPER) at Baylor University, Texas, and the Institute of Space Systems (IRS) at the University of Stuttgart, Germany, two plasma wind tunnel facilities of similar type have been established using the inductively heated plasma source IPG6 which is based on proven IRS designs. The facility at Baylor University (IPG6-B) works at a frequency of 13.56 MHz and a maximum power of 15 kW. A vacuum pump of 160m^3/h in combination with a butterfly valve allows pressure control in a wide range. First experiments have been conducted with Air, O2 and N2 as working gases and volumetric flow rates of up to 14 L/min at pressures of a few 100 Pa, although pressures below 1 Pa are achievable at lower flow rates. The maximum tested electric power so far was 8 kW. Plasma powers and total pressures in the plasma jet have been obtained. In the near future the set up of additional diagnostics, the use of other gases (i.e. H2, He), and the integration of a dust particle accelerator are planned. The intended fields of research are basic investigation in thermo-chemistry and plasma radiation, space plasma environments and high heat fluxes e.g. in fusion devices or during atmospheric entry of spacecraft. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014APS..GECET1004Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014APS..GECET1004Y">Measurement of OH, NO, O and N atoms in helium plasma jet for ROS/RNS controlled biomedical processes</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Yonemori, Seiya; Kamakura, Taku; Ono, Ryo 2014-10-01 Atmospheric-pressure plasmas are of emerging interest for new plasma applications such as cancer treatment, cell activation and sterilization. In those biomedical processes, reactive oxygen/nitrogen species (ROS/RNS) are said that they play significant role. It is though that active species give oxidative stress and induce biomedical reactions. In this study, we measured OH, NO, O and N atoms using laser induced fluorescence (LIF) measurement and found that voltage polarity affect particular ROS. When negative high voltage was applied to the plasma jet, O atom density was tripled compared to the case of positive applied voltage. In that case, O atom density was around 3 × 1015 [cm-3] at maximum. In contrast, OH and NO density did not change their density depending on the polarity of applied voltage, measured as in order of 1013 and 1014 [cm-3] at maximum, respectively. From ICCD imaging measurement, it could be seen that negative high voltage enhanced secondary emission in plasma bullet propagation and it can affect the effective production of particular ROS. Since ROS/RNS dose can be a quantitative criterion to control plasma biomedical application, those measurement results is able to be applied for in vivo and in vitro plasma biomedical experiments. This study is supported by the Grant-in-Aid for Science Research by the Ministry of Education, Culture, Sport, Science and Technology. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22614049-differential-rotation-plasma-gol-multiple-mirror-trap-during-injection-relativistic-electron-beam','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22614049-differential-rotation-plasma-gol-multiple-mirror-trap-during-injection-relativistic-electron-beam">Differential rotation of plasma in the GOL-3 multiple-mirror trap during injection of a relativistic electron beam</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Ivanov, I. A., E-mail: I.A.Ivanov@inp.nsk.su; Burdakov, A. V.; Burmasov, V. S. 2017-02-15 Results of spectral and magnetic diagnostics of plasma differential rotation in the GOL-3 multiplemirror trap are presented. It is shown that the maximum frequency of plasma rotation about the longitudinal axis reaches 0.5 MHz during the injection of a relativistic electron beam into the plasma. The data of two diagnostics agree if there is a region with a higher rotation frequency near the boundary of the electron beam. Plasma differential rotation can be an additional factor stabilizing interchange modes in the GOL-3 facility. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JASTP.171..250I','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JASTP.171..250I">Changes of atmospheric properties over Belgrade, observed using remote sensing and in situ methods during the partial solar eclipse of 20 March 2015</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Ilić, L.; Kuzmanoski, M.; Kolarž, P.; Nina, A.; Srećković, V.; Mijić, Z.; Bajčetić, J.; Andrić, M. 2018-06-01 Measurements of atmospheric parameters were carried out during the partial solar eclipse (51% coverage of solar disc) observed in Belgrade on 20 March 2015. The measured parameters included height of the planetary boundary layer (PBL), meteorological parameters, solar radiation, surface ozone and air ions, as well as Very Low Frequency (VLF, 3-30 kHz) and Low Frequency (LF, 30-300 kHz) signals to detect low-ionospheric plasma perturbations. The observed decrease of global solar and UV-B radiation was 48%, similar to the solar disc coverage. Meteorological parameters showed similar behavior at two measurement sites, with different elevations and different measurement heights. Air temperature change due to solar eclipse was more pronounced at the lower measurement height, showing a decrease of 2.6 °C, with 15-min time delay relative to the eclipse maximum. However, at the other site temperature did not decrease; its morning increase ceased with the start of the eclipse, and continued after the eclipse maximum. Relative humidity at both sites remained almost constant until the eclipse maximum and then decreased as the temperature increased. The wind speed decreased and reached minimum 35 min after the last contact. The eclipse-induced decrease of PBL height was about 200 m, with minimum reached 20 min after the eclipse maximum. Although dependent on UV radiation, surface ozone concentration did not show the expected decrease, possibly due to less significant influence of photochemical reactions at the measurement site and decline of PBL height. Air-ion concentration decreased during the solar eclipse, with minimum almost coinciding with the eclipse maximum. Additionally, the referential Line-of-Sight (LOS) radio link was set in the area of Belgrade, using the carrier frequency of 3 GHz. Perturbation of the receiving signal level (RSL) was observed on March 20, probably induced by the solar eclipse. Eclipse-related perturbations in ionospheric D-region were detected based on the VLF/LF signal variations, as a consequence of Lyα radiation decrease. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/9698284','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/9698284">Plasma growth hormone (GH), insulin and amino acid responses to arginine with or without aspartic acid in pigs. Effect of the dose.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Cochard, A; Guilhermet, R; Bonneau, M 1998-01-01 The aim of the present study was to examine, for the first time in pigs, the dose-dependent effect of arginine (ARG) on growth hormone (GH) and insulin release and the effect of the combined ARG and aspartic acid (ASP) treatment on GH and insulin release. ARG (0.5 or 1 g/kg body weight) with or without an equimolar supplement of ASP (0.38 or 0.76 g/kg, respectively) was administered in piglets via the duodenum. ARG increased plasma arginine, ornithine, urea, proline and branched chain amino acid concentrations. ASP increased specifically plasma aspartic acid, glutamic acid, alanine and citrulline concentrations. Plasma insulin increased with no apparent difference between treatments. Maximum GH level and the area under the GH curve (AUC) were increased in a dose-dependent manner in response to ARG treatment. GH response to the combined ARG and ASP treatment (ARGASP) was delayed compared to ARG alone and was not dose-dependent. AUC for GH after ARGASP treatments were intermediate between those observed after the two ARG doses. Our data suggest that high ASP doses transiently inhibit and delay ARG-induced GH release in pigs and that an equimolar supplement of ASP stimulates or inhibits ARG-induced GH release depending on the dose used. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016PhPl...23e2502Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016PhPl...23e2502Y">The study of heat flux for disruption on experimental advanced superconducting tokamak</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Yang, Zhendong; Fang, Jianan; Gong, Xianzu; Gan, Kaifu; Luo, Jiarong; Zhao, Hailin; Cui, Zhixue; Zhang, Bin; Chen, Meiwen 2016-05-01 Disruption of the plasma is one of the most dangerous instabilities in tokamak. During the disruption, most of the plasma thermal energy is lost, which causes damages to the plasma facing components. Infrared (IR) camera is an effective tool to detect the temperature distribution on the first wall, and the energy deposited on the first wall can be calculated from the surface temperature profile measured by the IR camera. This paper concentrates on the characteristics of heat flux distribution onto the first wall under different disruptions, including the minor disruption and the vertical displacement events (VDE) disruption. Several minor disruptions have been observed before the major disruption under the high plasma density in experimental advanced superconducting tokamak. During the minor disruption, the heat fluxes are mainly deposited on the upper/lower divertors. The magnetic configuration prior to the minor disruption is a lower single null with the radial distance between the two separatrices in the outer midplane dRsep = -2 cm, while it changes to upper single null (dRsep = 1.4 cm) during the minor disruption. As for the VDE disruption, the spatial distribution of heat flux exhibits strong toroidal and radial nonuniformity, and the maximum heat flux received on the dome plate can be up to 11 MW/m2. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26362831','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26362831">Correlations of plasma renin activity and aldosterone concentration with ambulatory blood pressure responses to nebivolol and valsartan, alone and in combination, in hypertension.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Giles, Thomas D; Bakris, George; Oparil, Suzanne; Weber, Michael A; Li, Huiling; Mallick, Madhuja; Bharucha, David B; Chen, ChunLin; Ferguson, William G 2015-11-01 After demonstration of the antihypertensive efficacy of the combination of the beta-blocker nebivolol and the angiotensin receptor blocker valsartan in an 8-week, randomized, placebo-controlled trial (N = 4161), we now report the effects of this treatment on the renin-angiotensin-aldosterone system in a substudy (n = 805). Plasma renin activity increased with valsartan (54%-73%) and decreased with nebivolol (51%-65%) and the combination treatment (17%-39%). Plasma aldosterone decreased with individual treatments (valsartan, 11%-22%; nebivolol, 20%-26%), with the largest reduction (35%) observed with maximum combination dose (20 mg nebivolol/320 mg valsartan). Baseline ln(plasma renin activity) correlated with the 8-week reductions in 24-hour systolic and diastolic BP following treatments with the combination (all doses combined, P = .003 and P < .001) and nebivolol (both, P < .001), but not with valsartan. Baseline ln(aldosterone) correlated with 24-hour systolic and diastolic BP reductions following combination treatment only (P < .001 and P = .005). The implications of the renin-angiotensin-aldosterone system effects of this beta blocker-angiotensin receptor blocker combination should be explored further. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li class="active">18</li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_19" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li class="active">19</li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="361"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2006APS..DPPNP1098H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2006APS..DPPNP1098H">Laser-produced plasma EUV source using a colloidal microjet target containing tin dioxide nanoparticles</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Higashiguchi, Takeshi; Dojyo, Naoto; Sasaki, Wataru; Kubodera, Shoichi 2006-10-01 We realized a low-debris laser-produced plasma extreme ultraviolet (EUV) source by use of a colloidal microjet target, which contained low-concentration (6 wt%) tin-dioxide nanoparticles. An Nd:YAG laser was used to produce a plasma at the intensity on the order of 10^11 W/cm^2. The use of low concentration nanoparticles in a microjet target with a diameter of 50 μm regulated the neutral debris emission from a target, which was monitored by a silicon witness plate placed 30 cm apart from the source in a vacuum chamber. No XPS signals of tin and/or oxygen atoms were observed on the plate after ten thousand laser exposures. The low concentration nature of the target was compensated and the conversion efficiency (CE) was improved by introducing double pulses of two Nd:YAG lasers operated at 532 and 1064 nm as a result of controlling the micro-plasma characteristics. The EUV CE reached its maximum of 1.2% at the delay time of approximately 100 ns with the main laser intensiy of 2 x10^11 W/cm^2. The CE value was comparable to that of a tin bulk target, which, however, produced a significant amount of neutral debris. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013JPlPh..79..405P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013JPlPh..79..405P">Future lunar missions and investigation of dusty plasma processes on the Moon</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Popel, Sergey I.; Zelenyi, Lev M.; Zelenyi 2013-08-01 From the Apollo era of exploration, it was discovered that sunlight was scattered at the terminators giving rise to ``horizon glow'' and ``streamers'' above the lunar surface. Subsequent investigations have shown that the sunlight was most likely scattered by electrostatically charged dust grains originating from the surface. A renaissance is being observed currently in investigations of the Moon. The Luna-Glob and Luna-Resource missions (the latter jointly with India) are being prepared in Russia. Some of these missions will include investigations of lunar dust. Here we discuss the future experimental investigations of lunar dust within the missions of Luna-Glob and Luna-Resource. We consider the dusty plasma system over the lunar surface and determine the maximum height of dust rise. We describe mechanisms of formation of the dusty plasma system over the Moon and its main properties, determine distributions of electrons and dust over the lunar surface, and show a possibility of rising dust particles over the surface of the illuminated part of the Moon in the entire range of lunar latitudes. Finally, we discuss the effect of condensation of micrometeoriod substance during the expansion of the impact plume and show that this effect is important from the viewpoint of explanation of dust particle rise to high altitudes in addition to the dusty plasma effects. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1997AIPC..409..611V','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1997AIPC..409..611V">Electron beam generation in the turbulent plasma of Z-pinch discharges</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Vikhrev, Victor V.; Baronova, Elena O. 1997-05-01 Numerical modeling of the process of electron beam generation in z-pinch discharges are presented. The proposed model represents the electron beam generation under turbulent plasma conditions. Strong current distribution inhomogeneity in the plasma column has been accounted for the adequate generation process investigation. Electron beam is generated near the maximum of compression due to run away mechanism and it is not related with the current break effect. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016APS..DPPBO7006G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016APS..DPPBO7006G">An Electrothermal Plasma Source Developed for Simulation of Transient Heat Loads in Future Large Fusion Devices</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Gebhart, Trey; Baylor, Larry; Winfrey, Leigh 2016-10-01 The realization of fusion energy requires materials that can withstand high heat and particle fluxes at the plasma material interface. In this work, an electrothermal (ET) plasma source has been designed as a possible transient heat flux source for a linear plasma material interaction device. An ET plasma source operates in the ablative arc regime, which is driven by a DC capacitive discharge. The current travels through the 4mm bore of a boron nitride liner and subsequently ablates and ionizes the liner material. This results in a high density plasma with a large unidirectional bulk flow out of the source exit. The pulse length for the ET source has been optimized using a pulse forming network to have a duration of 1ms at full-width half maximum. The peak currents and maximum source energies seen in this system are 2kA and 5kJ. The goal of this work is to show that the ET source produces electron densities and heat fluxes that are comparable to transient events in future large magnetic confinement fusion devices. Heat flux, plasma temperature, and plasma density were determined for each test shot using infrared imaging and optical spectroscopy techniques. This work will compare the ET source output (heat flux, temperature, and density) with and without an applied magnetic field. Research sponsored by the Laboratory Directed Research and Development Program of Oak Ridge National Laboratory, managed by UT-Battelle, LLC, for the U. S. Department of Energy. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013APS..DPPTP8057T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013APS..DPPTP8057T">Dust generation at interaction of plasma jet with surfaces</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Ticos, Catalin; Toader, Dorina; Banu, Nicoleta; Scurtu, Adrian; Oane, Mihai 2013-10-01 Coatings of W and C with widths of a few microns will be exposed to plasma jet for studying the erosion of the surface and detachment of micron size dust particles. A coaxial plasma gun has been built inside a vacuum chamber for producing supersonic plasma jets. Its design is based on a 50 kJ coaxial plasma gun which has been successfully used for accelerating hypervelocity dust. Initial shots were carried out for a capacitor bank with C = 12 μF and charged up to 2 kV. Currents of tens of amps were measured with a Rogowsky coil and plasma flow speeds of 4 km/s were inferred from high-speed images of jet propagation. An upgrade consisting in adding capacitors in parallel will be performed in order to increase the energy up to 2 kJ. A coil will be installed at the gun muzzle to compress the plasma flow and increase the energy density of the jet on the sample surface. A CCD camera with a maximum recording speed of 100 k fps and a maximum resolution of 1024 × 1024 pixels was set for image acquisition of the plasma and dust. A laser system used to illuminate the ejected dust from the surface includes a laser diode emitting at 650 nm with a beam power of 25 mW. The authors acknowledge support from EURATOM WP13-IPH-A03-P2-02-BS22. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/1406917-enhanced-reproducibility-mode-plasma-discharges-via-physics-model-based-profile-feedback-control-diii','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/1406917-enhanced-reproducibility-mode-plasma-discharges-via-physics-model-based-profile-feedback-control-diii">Enhanced reproducibility of L-mode plasma discharges via physics-model-based q-profile feedback control in DIII-D</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Schuster, Eugenio J.; Wehner, William P.; Barton, Joseph E. Recent experiments on DIII-D demonstrate the potential of physics-model-based q-profile control to improve reproducibility of plasma discharges. A combined feed forward + feedback control scheme is employed to optimize the current ramp-up phase by consistently achieving target q profiles (Target 1: q min = 1.3,q 95 = 4:4; Target 2: q min = 1.65,q 95 = 5.0; Target 3: q min = 2.1,q 95 = 6:2) at prescribed times during the plasma formation phase (Target 1: t = 1.5 s; Target 2: t = 1:3 s; Target 3: t = 1.0 s). At the core of the control scheme ismore » a nonlinear, first-principles-driven, physics-based, control-oriented model of the plasma dynamics valid for low confinement (L-mode) scenarios. To prevent undesired L-H transitions, a constraint on the maximum allowable total auxiliary power is imposed in addition to the maximum powers for the individual heating and current-drive sources. Experimental results are presented to demonstrate the effectiveness of the combined feed forward + feedback control scheme to consistently achieve the desired target profiles at the predefined times. Here, these results also show how the addition of feedback control significantly improves upon the feed forward only control solution by reducing the matching error and also how the feedback controller is able to reduce the matching error as the constraint on the maximum allowable total auxiliary power is relaxed while keeping the plasma in L-mode.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1406917-enhanced-reproducibility-mode-plasma-discharges-via-physics-model-based-profile-feedback-control-diii','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1406917-enhanced-reproducibility-mode-plasma-discharges-via-physics-model-based-profile-feedback-control-diii">Enhanced reproducibility of L-mode plasma discharges via physics-model-based q-profile feedback control in DIII-D</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a> Schuster, Eugenio J.; Wehner, William P.; Barton, Joseph E.; ... 2017-08-09 Recent experiments on DIII-D demonstrate the potential of physics-model-based q-profile control to improve reproducibility of plasma discharges. A combined feed forward + feedback control scheme is employed to optimize the current ramp-up phase by consistently achieving target q profiles (Target 1: q min = 1.3,q 95 = 4:4; Target 2: q min = 1.65,q 95 = 5.0; Target 3: q min = 2.1,q 95 = 6:2) at prescribed times during the plasma formation phase (Target 1: t = 1.5 s; Target 2: t = 1:3 s; Target 3: t = 1.0 s). At the core of the control scheme ismore » a nonlinear, first-principles-driven, physics-based, control-oriented model of the plasma dynamics valid for low confinement (L-mode) scenarios. To prevent undesired L-H transitions, a constraint on the maximum allowable total auxiliary power is imposed in addition to the maximum powers for the individual heating and current-drive sources. Experimental results are presented to demonstrate the effectiveness of the combined feed forward + feedback control scheme to consistently achieve the desired target profiles at the predefined times. Here, these results also show how the addition of feedback control significantly improves upon the feed forward only control solution by reducing the matching error and also how the feedback controller is able to reduce the matching error as the constraint on the maximum allowable total auxiliary power is relaxed while keeping the plasma in L-mode.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27432587','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27432587">In Vivo Arthroscopic Temperatures: A Comparison Between 2 Types of Radiofrequency Ablation Systems in Arthroscopic Anterior Cruciate Ligament Reconstruction-A Randomized Controlled Trial.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Matthews, Brent; Wilkinson, Matthew; McEwen, Peter; Hazratwala, Kaushik; Doma, Kenji; Manoharan, Varaguna; Bahho, Zaid; McEwen, Shannon 2017-01-01 To compare a plasma ablation device with a standard ablation device in anterior cruciate ligament (ACL) reconstruction to determine which system is superior in terms of intra-articular heat generation and diathermy efficiency. This was a prospective, randomized controlled trial. The inclusion criteria were adult patients undergoing primary ACL reconstruction. Patients were randomized preoperatively to the standard ablation group or the plasma ablation group. A thermometer was inserted into the inferior suprapatellar pouch, and the temperature, time, and duration of radiofrequency ablation were measured continually. No significant differences were found between the standard ablation system and the plasma ablation system for maximum temperature (29.77°C and 29.34°C, respectively; P = .95), mean temperature (26.16°C and 26.99°C, respectively; P = .44), minimum temperature (22.66°C and 23.94°C, respectively; P = .54), and baseline temperature (26.80°C and 27.93°C, respectively; P = .35). Similarly, no significant differences were found for operative time (82.90 minutes and 80.50 minutes, respectively; P = .72) and mean diathermy activation times (2.6 minutes for both systems; P = .90). The between-system coefficient of variation for the measured parameters ranged from 0.12% to 3.69%. No intra-articular readings above the temperature likely to damage chondrocytes were recorded. The mean irrigation fluid temperature had a significant correlation with the maximum temperature reached during the procedure (Spearman rank correlation, r = 0.87; P < .01). No difference in temperature was observed between the standard ablation and plasma ablation probes during ACL reconstruction. Temperatures did not exceed critical temperatures associated with chondrocyte death. Level I, randomized controlled trial. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016ApJ...820L...9K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016ApJ...820L...9K">RadioAstron Observations of the Quasar 3C273: A Challenge to the Brightness Temperature Limit</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kovalev, Y. Y.; Kardashev, N. S.; Kellermann, K. I.; Lobanov, A. P.; Johnson, M. D.; Gurvits, L. I.; Voitsik, P. A.; Zensus, J. A.; Anderson, J. M.; Bach, U.; Jauncey, D. L.; Ghigo, F.; Ghosh, T.; Kraus, A.; Kovalev, Yu. A.; Lisakov, M. M.; Petrov, L. Yu.; Romney, J. D.; Salter, C. J.; Sokolovsky, K. V. 2016-03-01 Inverse Compton cooling limits the brightness temperature of the radiating plasma to a maximum of 1011.5 K. Relativistic boosting can increase its observed value, but apparent brightness temperatures much in excess of 1013 K are inaccessible using ground-based very long baseline interferometry (VLBI) at any wavelength. We present observations of the quasar 3C 273, made with the space VLBI mission RadioAstron on baselines up to 171,000 km, which directly reveal the presence of angular structure as small as 26 μas (2.7 light months) and brightness temperature in excess of 1013 K. These measurements challenge our understanding of the non-thermal continuum emission in the vicinity of supermassive black holes and require a much higher Doppler factor than what is determined from jet apparent kinematics. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19850052710&hterms=Biddle&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3DBiddle','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19850052710&hterms=Biddle&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3DBiddle">Auroral zone effects on hydrogen geocorona structure and variability</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Moore, T. E.; Biddle, A. P.; Waite, J. H., Jr.; Killeen, T. L. 1985-01-01 The effect of diurnal and magnetospheric modulations on the structure of the hydrogen geocorona is analyzed on the basis of recent observations. Particular attention is given to the enhancement of neutral escape by plasma effects, including the recently observed phenomenon of low-altitude ion acceleration. It is found that, while significant fluxes of neutral H should be produced by transverse ion acceleration in the auroral zone, the process is probably insufficient to account for the observed polar depletion of hydrogen atoms. Analysis of recent exospheric temperature measurements from the Dynamics Explorer-2 satellite suggest that neutral heating in and near the high latitude cusp may be the major contributor to depleted atomic hydrogen densities at high latitudes. Altitude profiles of the production rates for escaping neutral hydrogen atoms during periods of maximum, minimum, and typical solar activity are provided. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/21452916-quiescent-prominence-dynamics-observed-hinode-solar-optical-telescope-turbulent-upflow-plumes','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/21452916-quiescent-prominence-dynamics-observed-hinode-solar-optical-telescope-turbulent-upflow-plumes">QUIESCENT PROMINENCE DYNAMICS OBSERVED WITH THE HINODE SOLAR OPTICAL TELESCOPE. I. TURBULENT UPFLOW PLUMES</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Berger, Thomas E.; Slater, Gregory; Hurlburt, Neal 2010-06-20 Hinode/Solar Optical Telescope (SOT) observations reveal two new dynamic modes in quiescent solar prominences: large-scale (20-50 Mm) 'arches' or 'bubbles' that 'inflate' from below into prominences, and smaller-scale (2-6 Mm) dark turbulent upflows. These novel dynamics are related in that they are always dark in visible-light spectral bands, they rise through the bright prominence emission with approximately constant speeds, and the small-scale upflows are sometimes observed to emanate from the top of the larger bubbles. Here we present detailed kinematic measurements of the small-scale turbulent upflows seen in several prominences in the SOT database. The dark upflows typically initiate verticallymore » from 5 to 10 Mm wide dark cavities between the bottom of the prominence and the top of the chromospheric spicule layer. Small perturbations on the order of 1 Mm or less in size grow on the upper boundaries of cavities to generate plumes up to 4-6 Mm across at their largest widths. All plumes develop highly turbulent profiles, including occasional Kelvin-Helmholtz vortex 'roll-up' of the leading edge. The flows typically rise 10-15 Mm before decelerating to equilibrium. We measure the flowfield characteristics with a manual tracing method and with the Nonlinear Affine Velocity Estimator (NAVE) 'optical flow' code to derive velocity, acceleration, lifetime, and height data for several representative plumes. Maximum initial speeds are in the range of 20-30 km s{sup -1}, which is supersonic for a {approx}10,000 K plasma. The plumes decelerate in the final few Mm of their trajectories resulting in mean ascent speeds of 13-17 km s{sup -1}. Typical lifetimes range from 300 to 1000 s ({approx}5-15 minutes). The area growth rate of the plumes (observed as two-dimensional objects in the plane of the sky) is initially linear and ranges from 20,000 to 30,000 km{sup 2} s{sup -1} reaching maximum projected areas from 2 to 15 Mm{sup 2}. Maximum contrast of the dark flows relative to the bright prominence plasma in SOT images is negative and ranges from -10% for smaller flows to -50% for larger flows. Passive scalar 'cork movies' derived from NAVE measurements show that prominence plasma is entrained by the upflows, helping to counter the ubiquitous downflow streams in the prominence. Plume formation shows no clear temporal periodicity. However, it is common to find 'active cavities' beneath prominences that can spawn many upflows in succession before going dormant. The mean flow recurrence time in these active locations is roughly 300-500 s (5-8 minutes). Locations remain active on timescales of tens of minutes up to several hours. Using a column density ratio measurement and reasonable assumptions on plume and prominence geometries, we estimate that the mass density in the dark cavities is at most 20% of the visible prominence density, implying that a single large plume could supply up to 1% of the mass of a typical quiescent prominence. We hypothesize that the plumes are generated from a Rayleigh-Taylor instability taking place on the boundary between the buoyant cavities and the overlying prominence. Characteristics, such as plume size and frequency, may be modulated by the strength and direction of the cavity magnetic field relative to the prominence magnetic field. We conclude that buoyant plumes are a source of quiescent prominence mass as well as a mechanism by which prominence plasma is advected upward, countering constant gravitational drainage.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010ApJ...716.1288B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010ApJ...716.1288B">Quiescent Prominence Dynamics Observed with the Hinode Solar Optical Telescope. I. Turbulent Upflow Plumes</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Berger, Thomas E.; Slater, Gregory; Hurlburt, Neal; Shine, Richard; Tarbell, Theodore; Title, Alan; Lites, Bruce W.; Okamoto, Takenori J.; Ichimoto, Kiyoshi; Katsukawa, Yukio; Magara, Tetsuya; Suematsu, Yoshinori; Shimizu, Toshifumi 2010-06-01 Hinode/Solar Optical Telescope (SOT) observations reveal two new dynamic modes in quiescent solar prominences: large-scale (20-50 Mm) "arches" or "bubbles" that "inflate" from below into prominences, and smaller-scale (2-6 Mm) dark turbulent upflows. These novel dynamics are related in that they are always dark in visible-light spectral bands, they rise through the bright prominence emission with approximately constant speeds, and the small-scale upflows are sometimes observed to emanate from the top of the larger bubbles. Here we present detailed kinematic measurements of the small-scale turbulent upflows seen in several prominences in the SOT database. The dark upflows typically initiate vertically from 5 to 10 Mm wide dark cavities between the bottom of the prominence and the top of the chromospheric spicule layer. Small perturbations on the order of 1 Mm or less in size grow on the upper boundaries of cavities to generate plumes up to 4-6 Mm across at their largest widths. All plumes develop highly turbulent profiles, including occasional Kelvin-Helmholtz vortex "roll-up" of the leading edge. The flows typically rise 10-15 Mm before decelerating to equilibrium. We measure the flowfield characteristics with a manual tracing method and with the Nonlinear Affine Velocity Estimator (NAVE) "optical flow" code to derive velocity, acceleration, lifetime, and height data for several representative plumes. Maximum initial speeds are in the range of 20-30 km s-1, which is supersonic for a ~10,000 K plasma. The plumes decelerate in the final few Mm of their trajectories resulting in mean ascent speeds of 13-17 km s-1. Typical lifetimes range from 300 to 1000 s (~5-15 minutes). The area growth rate of the plumes (observed as two-dimensional objects in the plane of the sky) is initially linear and ranges from 20,000 to 30,000 km2 s-1 reaching maximum projected areas from 2 to 15 Mm2. Maximum contrast of the dark flows relative to the bright prominence plasma in SOT images is negative and ranges from -10% for smaller flows to -50% for larger flows. Passive scalar "cork movies" derived from NAVE measurements show that prominence plasma is entrained by the upflows, helping to counter the ubiquitous downflow streams in the prominence. Plume formation shows no clear temporal periodicity. However, it is common to find "active cavities" beneath prominences that can spawn many upflows in succession before going dormant. The mean flow recurrence time in these active locations is roughly 300-500 s (5-8 minutes). Locations remain active on timescales of tens of minutes up to several hours. Using a column density ratio measurement and reasonable assumptions on plume and prominence geometries, we estimate that the mass density in the dark cavities is at most 20% of the visible prominence density, implying that a single large plume could supply up to 1% of the mass of a typical quiescent prominence. We hypothesize that the plumes are generated from a Rayleigh-Taylor instability taking place on the boundary between the buoyant cavities and the overlying prominence. Characteristics, such as plume size and frequency, may be modulated by the strength and direction of the cavity magnetic field relative to the prominence magnetic field. We conclude that buoyant plumes are a source of quiescent prominence mass as well as a mechanism by which prominence plasma is advected upward, countering constant gravitational drainage. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/12646763','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/12646763">Comparative single-dose pharmacokinetics of clonazepam following intravenous, intramuscular and oral administration to healthy volunteers.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Crevoisier, C; Delisle, M C; Joseph, I; Foletti, G 2003-01-01 The objective was to assess the single-dose pharmacokinetics of clonazepam following i.m., p.o. and i.v. administration. In an open-label, three-way crossover study, 12 healthy volunteers were randomized to receive a single dose of 2 mg clonazepam either by the i.m., p.o. or i.v. route. Serial blood samples were collected up to 120 h after drug administration. Plasma concentrations of clonazepam were determined by electron-capture gas-liquid chromatography. The absorption rates of clonazepam after i.m. and p.o. administration of clonazepam were significantly different from each other, as reflected by the respective mean values of maximum plasma concentration (C(max) 11.0 vs. 14.9 ng.ml(-1)) and time to reach maximum concentration (t(max) 3.1 vs. 1.7 h). Secondary plasma peaks of clonazepam were observed in 9 volunteers after i.m. injection (C(max) 9.9 ng.ml(-1); t(max) 10.4 h). A comparison of the area under the plasma concentration-time curves (AUC) shows that the i.m. route is equivalent to the oral route (AUC(0- infinity ) 620 vs. 561 ng.h.ml(-1)). Clonazepam was almost completely absorbed after i.m. and p.o. administration, as shown by the mean absolute bioavailability of 93 and 90%, respectively. No significant differences existed between the elimination half-lives (i.v. 38.0 h; i.m. 43.6 h; p.o. 39.0 h). The average clearance and volume of distribution (V(Z)) were 55 ml.min(-1) and 180 liters, respectively. In conclusion, the observed differences in C(max) and t(max) after i.m. and p.o. administration were consistent with a slower absorption rate of clonazepam after i.m. injection. The systemic exposure to clonazepam was not affected by the route of extravascular administration. Statistical evaluation of these kinetic data showed differences in the absorption rate, so that clonazepam given by the i.m. route is not bioequivalent to the oral route. On the basis of the results of this study, we would recommend the same i.m. and p.o. dose in epileptic patients, but therapeutic response would be expected to be less predictable and to occur later in the case of i.m. administration. Copyright 2003 S. Karger AG, Basel </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018AnGeo..36..473H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018AnGeo..36..473H">Simultaneous 6300 Å airglow and radar observations of ionospheric irregularities and dynamics at the geomagnetic equator</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Hickey, Dustin A.; Martinis, Carlos R.; Mendillo, Michael; Baumgardner, Jeffrey; Wroten, Joei; Milla, Marco 2018-03-01 In March 2014 an all-sky imager (ASI) was installed at the Jicamarca Radio Observatory (11.95° S, 76.87° W; 0.3° S MLAT). We present results of equatorial spread F (ESF) characteristics observed at Jicamarca and at low latitudes. Optical 6300 and 7774 Å airglow observations from the Jicamarca ASI are compared with other collocated instruments and with ASIs at El Leoncito, Argentina (31.8° S, 69.3° W; 19.8° S MLAT), and Villa de Leyva, Colombia (5.6° N, 73.52° W; 16.4° N MLAT). We use Jicamarca radar data, in incoherent and coherent modes, to obtain plasma parameters and detect echoes from irregularities. We find that ESF depletions tend to appear in groups with a group-to-group separation around 400-500 km and within-group separation around 50-100 km. We combine data from the three ASIs to investigate the conditions at Jicamarca that could lead to the development of high-altitude, or topside, plumes. We compare zonal winds, obtained from a Fabry-Pérot interferometer, with plasma drifts inferred from the zonal motion of plasma depletions. In addition to the ESF studies we also investigate the midnight temperature maximum and its effects at higher latitudes, visible as a brightness wave at El Leoncito. The ASI at Jicamarca along with collocated and low-latitude instruments provide a clear two-dimensional view of spatial and temporal evolution of ionospheric phenomena at equatorial and low latitudes that helps to explain the dynamics and evolution of equatorial ionospheric/thermospheric processes. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26945692','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26945692">A comparison of plasma levobupivacaine concentrations following transversus abdominis plane block and rectus sheath block.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Yasumura, R; Kobayashi, Y; Ochiai, R 2016-05-01 Levobupivacaine is commonly used as the local anaesthetic of choice in peripheral nerve blocks, but its pharmacokinetics have not been fully investigated. We compared the changes in plasma concentrations of levobupivacaine following transversus abdominis plane block and rectus sheath block. Fifty woman undergoing laparoscopy were randomly allocated to receive either a transversus abdominis plane block or an rectus sheath block. In both groups, 2.5 mg.kg(-1) levobupivacaine was administered, and blood samples were obtained 15 min, 30 min, 60 min and 120 min after injection. The mean maximum plasma concentration (Cmax) and mean time to reach Cmax (Tmax) as determined by non-linear regression analysis were 1.05 μg.ml(-1) and 32.4 min in the transversus abdominis plane group and 0.95 μg.ml(-1) and 60.9 min in the rectus sheath group, respectively. The plasma concentration of levobupivacaine peaked earlier in the transversus abdominis plane group than in the rectus sheath group and the maximum plasma concentration depended on the dose administered but not the procedure. © 2016 The Association of Anaesthetists of Great Britain and Ireland. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19896982','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19896982">Fasting plasma levels of nesfatin-1 in patients with type 1 and type 2 diabetes mellitus and the nutrient-related fluctuation of nesfatin-1 level in normal humans.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Li, Qing-Chun; Wang, Hai-Yan; Chen, Xi; Guan, Hong-Zai; Jiang, Zheng-Yao 2010-01-08 The novel satiety factor nesfatin-1 has been shown to decrease food intake and body weight in rodents after i.c.v. injection. However, no further developments regarding the true patho-physiological relevance of nesfatin-1 in obesity and type 1 diabetes mellitus (T1 DM) and type 2 diabetes mellitus (T2 DM) have been reported. A recent study by Stengel et al. demonstrated that a down-regulation of NUCB2 mRNA in gastric endocrine cells was observed after 24-h fasting. They raised the possibility that nesfatin/NUCB2 gene expression may be regulated by nutritional status, suggesting that nesfatin-1 in the stomach might play a role in satiety. In the present study, fasting levels in plasma nesfatin-1, insulin and glucose were measured and analyzed in healthy subjects and in patients with T1 DM and T2 DM. Plasma nesfatin-1 levels were measured 6 times before and after oral glucose ingestion in healthy subjects. No sex differences in plasma nesfatin-1 were found. The mean fasting plasma nesfatin-1 levels were slightly but not significantly higher in T1 DM patients compared to healthy subjects. However, fasting plasma nesfatin-1 levels were significantly lower in T2 DM patients compared to healthy subjects and T1 DM patients. Plasma nesfatin-1 did not change acutely, although a small rise in circulating nesfatin-1 occurred within 30 min after the beginning of an oral glucose ingestion (from a mean basal value of 0.99+/-0.23 ng/ml to a maximum of 1.08+/-0.24 ng/ml). No significant difference in plasma nesfatin-1 before and after an oral glucose was observed. In conclusion, we showed that fasting nesfatin-1 was significantly lower in T2 DM patients compared to healthy subjects and T1 DM patients. The significance of this result is unclear but the reduction in fasting nesfatin-1 may be one of the appetite-related hormones involved in diabetic hyperphagia. In addition, neither glucose nor saline ingestions affected plasma nesfatin-1, suggesting that gastric chemosensation is not sufficient for the nesfatin-1 response under the present conditions. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22408285-oscillating-two-stream-instability-magnetized-electron-positron-ion-plasma','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22408285-oscillating-two-stream-instability-magnetized-electron-positron-ion-plasma">Oscillating two-stream instability in a magnetized electron-positron-ion plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Tinakiche, Nouara; Faculty of Physics, U.S.T.H.B, Algiers 16111; Annou, R. 2015-04-15 Oscillating two-stream instability (OTSI) in a magnetized electron-ion plasma has been thoroughly studied, e.g., in ionospheric heating experiments [C. S. Liu and V. K. Tripathi, Interaction of Electromagnetic Waves With Electron Beams and Plasmas (World Scientific, 1994); V. K. Tripathi and P. V. Siva Rama Prasad, J. Plasma Phys. 41, 13 (1989); K. Ramachandran and V. K. Tripathi, IEEE Trans. Plasma Sci. 25, 423 (1997)]. In this paper, OTSI is investigated in a magnetized electron-positron-ion plasma. The dispersion relation of the process is established. The pump field threshold, along with the maximum growth rate of the instability is assessed usingmore » the Arecibo and HAARP parameters.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015PhPl...22d2101T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015PhPl...22d2101T">Oscillating two-stream instability in a magnetized electron-positron-ion plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Tinakiche, Nouara; Annou, R. 2015-04-01 Oscillating two-stream instability (OTSI) in a magnetized electron-ion plasma has been thoroughly studied, e.g., in ionospheric heating experiments [C. S. Liu and V. K. Tripathi, Interaction of Electromagnetic Waves With Electron Beams and Plasmas (World Scientific, 1994); V. K. Tripathi and P. V. Siva Rama Prasad, J. Plasma Phys. 41, 13 (1989); K. Ramachandran and V. K. Tripathi, IEEE Trans. Plasma Sci. 25, 423 (1997)]. In this paper, OTSI is investigated in a magnetized electron-positron-ion plasma. The dispersion relation of the process is established. The pump field threshold, along with the maximum growth rate of the instability is assessed using the Arecibo and HAARP parameters. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013ITPS...41..799L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013ITPS...41..799L">Glow and Dust in Plasma Boundaries</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Land, Victor; Douglass, Angela; Qiao, Ke; Zhang, Zhuanhao; Matthews, Lorin S.; Hyde, Truell 2013-04-01 The sheath region is probed in different complex plasma experiments using dust particles in addition to measurement of the optical emission originating from the plasma. The local maximum in optical emission coincides with the breaking of quasi-neutrality at the sheath boundary as indicated by the vertical force profile reconstructed from dust particle trajectories, as well as by the local onset of dust density waves in high density dust clouds suspended in a dielectric box. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27488574','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27488574">A randomized crossover study to assess the pharmacokinetics of a novel amphetamine extended-release orally disintegrating tablet in healthy adults.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Stark, Jeffrey G; Engelking, Dorothy; McMahen, Russ; Sikes, Carolyn 2016-09-01 In this pharmacokinetic (PK) study in healthy adults, we sought to: (1) compare the PK properties of a novel amphetamine extended-release orally disintegrating tablet formulation (Adzenys XR-ODT™ [AMP XR-ODT]) to a reference extended-release mixed amphetamine salts (MAS ER) formulation and (2) assess the effect of food on AMP XR-ODT. Forty-two adults were enrolled in a single-dose, open-label, 3-period, 3-treatment, randomized crossover study and received an 18.8-mg dose of AMP XR-ODT (fasted or fed) or equivalent dose (30 mg) of MAS ER (fasted). Plasma samples were analyzed for d-and l-amphetamine. Maximum plasma concentration (Cmax), time to maximum plasma concentration (Tmax), elimination half-life (T1/2), area under the concentration-time curve from time zero to last quantifiable concentration (AUClast), from time zero to infinity (AUCinf), relevant partial AUCs, and weight-normalized clearance (CL/F/kg) were assessed. The PK parameters were compared across treatments using an ANOVA. Safety was also assessed. A total of 39 adults completed this study. The geometric mean ratios (90% confidence interval [CI]) for AMP XR-ODT/MAS ER Cmax, AUC5-last, AUClast, and AUCinf were within 80%-125% for both d-and l-amphetamine. The 90% CIs for AUC0-5 were slightly below the 80%-125% range. When AMP XR-ODT was administered with food, there was a slight decrease in the d-and l-amphetamine Cmax and approximately a 2-hour delay in Tmax. The most common adverse events reported (>5% of participants) were dry mouth, palpitations, nausea, dizziness, headache, anxiety, and nasal congestion. AMP XR-ODT displayed a PK profile similar to MAS ER, and no clinically relevant food effect was observed. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li class="active">19</li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_20" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li class="active">20</li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="381"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15328251','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15328251">Multiple night-time doses of valerian (Valeriana officinalis) had minimal effects on CYP3A4 activity and no effect on CYP2D6 activity in healthy volunteers.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Donovan, Jennifer L; DeVane, C Lindsay; Chavin, Kenneth D; Wang, Jun-Sheng; Gibson, Bryan B; Gefroh, Holly A; Markowitz, John S 2004-12-01 Valerian (Valeriana officinalis) is a popular dietary supplement. The objective of this study was to assess the influence of a valerian extract on the activity of the drug-metabolizing enzymes cytochrome P450 2D6 (CYP2D6) and 3A4. Probe drugs dextromethorphan (30 mg; CYP2D6 activity) and alprazolam (2 mg; CYP3A4 activity) were administered orally to healthy volunteers (n = 12) at baseline and again after exposure to two 500-mg valerian tablets (1000 mg) nightly for 14 days. The valerian supplement contained a total valerenic acid content of 5.51 mg/tablet. Dextromethorphan to dextorphan metabolic ratios (DMRs) and alprazolam pharmacokinetics were determined at baseline and after valerian treatment. The DMR was 0.214 +/- 0.025 at baseline and 0.254 +/- 0.026 after valerian supplementation (p > 0.05). For alprazolam, the maximum concentration in plasma was significantly increased after treatment with valerian (25 +/- 7 ng/ml versus 31 +/- 8 ng/ml; p < 0.05). There were no significant differences in other pharmacokinetic parameters at baseline and after valerian exposure (all p values > or = 0.05; time to reach maximum concentration in plasma, 3.0 +/- 3.2 versus 3.1 +/- 2.1 h; area under the plasma concentration versus time curve, 471 +/- 183 versus 539 +/- 240 hx ng x ml(-1); half-life of elimination, 13.5 +/- 4.3 versus 12.2 +/- 5.6 h). Our results indicate that although a modest increase was observed in the alprazolam Cmax, typical doses of valerian are unlikely to produce clinically significant effects on the disposition of medications dependent on the CYP2D6 or CYP3A4 pathways of metabolism. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016cosp...41E1882T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016cosp...41E1882T">Spectral and Temporal Characteristics of LS PEG and TW PIC Using XMM-NEWTON Data</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Talebpour Sheshvan, Nasrin; Balman, Solen 2016-07-01 We report the analysis of archival XMM-Newton X-ray observations of LS Peg and TW Pic. These are Cataclysmic Variables (CVs) suggested as Intermediate Polars (IPs), but unconfirmed in the X-rays. Identification of several periodic oscillations in the optical band hint them as IPs. Unlike the previous spectral analysis on the EPIC-MOS data by fitting a hot optically thin plasma emission model with a single temperature for LS Peg, we simultaneously fitted all EPIC spectrum (pn+MOS) using a composite model of absorption for interstellar medium (tbabs) with two different partial covering absorbers (pcfabs) including a multitemperature plasma emission component (cevmkl) and a Gaussian emission line at 6.4 keV. TW Pic is best modeled in a similar manner with only one partial covering absorber and an extra Gaussian emission line at 6.7 keV. LS Peg has a maximum plasma temperature of ˜14.8 keV with an X-ray luminosity of ˜5×10^{32}ergs ^{-1} translating to an accretion rate of ˜1.27×10^{-10}M _{⊙}yr ^{-1}. TW Pic shows kT _{max} ˜38.7 keV with an X-ray luminosity around 1.6×10^{33}ergs ^{-1} at an accretion rate of ˜4×10^{-10}M _{⊙}yr ^{-1}. In addition, we discuss orbital modulations in the X-rays and power spectral analysis, and derive the EPIC pn spectra for orbital minimum and orbital maximum phases for both sources. We elaborate on the geometry of accretion and absorption in the X-ray emitting regions of both sources with articulation on the magnetic nature. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19800015869','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19800015869">Inert gas thrusters</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Kaufman, H. R.; Robinson, R. S. 1979-01-01 Inert gas thrusters considered for space propulsion systems were investigated. Electron diffusion across a magnetic field was examined utilizing a basic model. The production of doubly charged ions was correlated using only overall performance parameters. The use of this correlation is therefore possible in the design stage of large gas thrusters, where detailed plasma properties are not available. Argon hollow cathode performance was investigated over a range of emission currents, with the positions of the inert, keeper, and anode varied. A general trend observed was that the maximum ratio of emission to flow rate increased at higher propellant flow rates. It was also found that an enclosed keeper enhances maximum cathode emission at high flow rates. The maximum cathode emission at a given flow rate was associated with a noisy high voltage mode. Although this mode has some similarities to the plume mode found at low flows and emissions, it is encountered by being initially in the spot mode and increasing emission. A detailed analysis of large, inert-gas thruster performance was carried out. For maximum thruster efficiency, the optimum beam diameter increases from less than a meter at under 2000 sec specific impulse to several meters at 10,000 sec. The corresponding range in input power ranges from several kilowatts to megawatts. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012ApJ...755...68S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012ApJ...755...68S">Acceleration in Perpendicular Relativistic Shocks for Plasmas Consisting of Leptons and Hadrons</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Stockem, A.; Fiúza, F.; Fonseca, R. A.; Silva, L. O. 2012-08-01 We investigate the acceleration of light particles in perpendicular shocks for plasmas consisting of a mixture of leptonic and hadronic particles. Starting from the full set of conservation equations for the mixed plasma constituents, we generalize the magnetohydrodynamical jump conditions for a multi-component plasma, including information about the specific adiabatic constants for the different species. The impact of deviations from the standard model of an ideal gas is compared in theory and particle-in-cell simulations, showing that the standard MHD model is a good approximation. The simulations of shocks in electron-positron-ion plasmas are for the first time multi-dimensional, transverse effects are small in this configuration, and one-dimensional (1D) simulations are a good representation if the initial magnetization is chosen high. 1D runs with a mass ratio of 1836 are performed, which identify the Larmor frequency ω ci as the dominant frequency that determines the shock physics in mixed component plasmas. The maximum energy in the non-thermal tail of the particle spectra evolves in time according to a power law vpropt α with α in the range 1/3 < α < 1, depending on the initial parameters. A connection is made with transport theoretical models by Drury and Gargaté & Spitkovsky, which predict an acceleration time vpropγ and the theory for small wavelength scattering by Kirk & Reville, which predicts a behavior rather as vpropγ2. Furthermore, we compare different magnetic field orientations with B 0 inside and out of the plane, observing qualitatively different particle spectra than in pure electron-ion shocks. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JPhD...51i4001L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JPhD...51i4001L">CO2 conversion in non-thermal plasma and plasma/g-C3N4 catalyst hybrid processes</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Lu, Na; Sun, Danfeng; Zhang, Chuke; Jiang, Nan; Shang, Kefeng; Bao, Xiaoding; Li, Jie; Wu, Yan 2018-03-01 Carbon dioxide conversion at atmosphere pressure and low temperature has been studied in a cylindrical dielectric barrier discharge (DBD) reactor. Pure CO2 feed flows to the discharge zone and typical filamentary discharges were obtained in each half-cycle of the applied voltage. The gas temperature increased with discharge time and discharge power, which was found to affect the CO2 decomposition deeply. As the DBD reactor was cooled to ambient temperature, both the conversion of CO2 and the CO yield were enhanced. Especially the energy efficiencies changed slightly with the increase of discharge power and were much higher in cooling condition comparing to those without cooling. At a discharge power of 40 W, the energy efficiency under cooling condition was approximately six times more than that without cooling. Gas flow rate was observed to affect CO2 conversion and 0.1 L min-1 was obtained as optimum gas flow rate under cooling condition. In addition, the CO2 conversion rate in plasma/g-C3N4 catalyst hybrid system was twice times as that in plasma-alone system. In case of cooling, the existence of g-C3N4 catalyst contributed to a 47% increase of CO2 conversion compared to the sole plasma process. The maximum energy-efficiency with g-C3N4 was 0.26 mmol kJ-1 at 20 W, which increased by 157% compared to that without g-C3N4. The synergistic effect of DBD plasma with g-C3N4 on pure CO2 conversion was verified. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017OptLT..97...60H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017OptLT..97...60H">Spatial confinement effects on spectroscopic and morphological studies of nanosecond laser-ablated Zirconium</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Hayat, Asma; Bashir, Shazia; Rafique, Muhammad Shahid; Ahmad, Riaz; Akram, Mahreen; Mahmood, Khaliq; Zaheer, Ali 2017-12-01 Spatial confinement effects on plasma parameters and surface morphology of laser ablated Zr (Zirconium) are studied by introducing a metallic blocker. Nd:YAG laser at various fluencies ranging from 8 J cm-2 to 32 J cm-2 was employed as an irradiation source. All measurements were performed in the presence of Ar under different pressures. Confinement effects offered by metallic blocker are investigated by placing the blocker at different distances of 6 mm, 8 mm and 10 mm from the target surface. It is revealed from LIBS analysis that both plasma parameters i.e. excitation temperature and electron number density increase with increasing laser fluence due to enhancement in energy deposition. It is also observed that spatial confinement offered by metallic blocker is responsible for the enhancement of both electron temperature and electron number density of Zr plasma. This is true for all laser fluences and pressures of Ar. Maximum values of electron temperature and electron number density without blocker are 12,600 K and 14 × 1017 cm-3 respectively whereas, these values are enhanced to 15,000 K and 21 × 1017 cm-3 in the presence of blocker. The physical mechanisms responsible for the enhancement of Zr plasma parameters are plasma compression, confinement and pronounced collisional excitations due to reflection of shock waves. Scanning Electron Microscope (SEM) analysis was performed to explore the surface morphology of laser ablated Zr. It reveals the formation of cones, cavities and ripples. These features become more distinct and well defined in the presence of blocker due to plasma confinement. The optimum combination of blocker distance, fluence and Ar pressure can identify the suitable conditions for defining the role of plasma parameters for surface structuring. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15950411','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15950411">A lecithin-based microemulsion of rh-insulin with aprotinin for oral administration: Investigation of hypoglycemic effects in non-diabetic and STZ-induced diabetic rats.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Cilek, A; Celebi, N; Tirnaksiz, F; Tay, A 2005-07-14 The aim of this study was to develop a microemulsion formulation providing an improved efficacy of orally administered insulin. The microemulsions were prepared using Labrafil M 1944 CS, Phospholipon 90 G (lecithin), absolute alcohol and bi-distilled water. The microemulsions of recombinant human (rh)-insulin and aqueous solution (200 IU/kg) were administered intragastrically by a canulla to diabetic and non-diabetic rats. Aprotinin (2500 KIU/g) was added as the enzyme inhibitor to the formulation. Upon the administration of intragastric rh-insulin solution (IS) to non-diabetic rats, the plasma glucose and insulin levels were not changed significantly. Therefore, the hypoglycemic effect caused by subcutaneous rh-insulin solution (SC), microemulsion containing rh-insulin (IME) and microemulsion containing rh-insulin and aprotinin (IMEA) were analyzed in diabetic rats. The area above the plasma glucose levels time curves (AAC), minimum glucose concentration (Cmin) and time to Cmin (tmin) were derived from the plasma glucose profiles. IME and IMEA caused approximately 30% decrease in plasma glucose levels. The decrease in the plasma glucose levels continued after the 90th min. The highest AAC value was obtained when IMEA was administered to rats. The maximum plasma insulin concentration (Cmax), time to reach Cmax (tmax), terminal half-life (t(1/2)), area under the plasma concentration-time curve (AUC), mean residence time (MRT) and elimination rate constant (k(el)) values were also calculated. It was observed that t(1/2) values varied between 0.53 and 1.31h. No significant difference could be found between the pharmacokinetic parameters of the IME and IMEA administered groups. Addition of aprotinin to the microemulsion containing rh-insulin increased bioavailability when compared to those not containing it, although the difference is not significant. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018R%26QE...60..609T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018R%26QE...60..609T">On Spatial Structuring of the F2 Layer Studied by the Satellite Radio Sounding of the Ionosphere Disturbed by High-Power HF Radio Waves</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Tereshchenko, E. D.; Turyansky, V. A.; Khudukon, B. Z.; Yurik, R. Yu.; Frolov, V. L. 2018-01-01 We present the results of studying the characteristics of the artificial plasma structures excited in the ionospheric F2 region modified by high-power HF radio waves. The experiments were carried out at the Sura heating facility using satellite radio sounding of the ionosphere. The plasma density profile was reconstructed with the highest possible spatial resolution for today, about 4 km. In a direction close to the magnetic zenith of the pump wave, the following phenomena were observed: the formation of a cavity with a 15% lower plasma density at the altitudes of the F2 layer and below; the formation of an area with plasma density increased by 12% at altitudes greater than 400 km. With a long-term quasiperiodic impact of the pump wave on the ionosphere, wavy large-scale electron-density perturbations (the meridional scale λx ≈ 130 km and the vertical scale λz ≈ 440 km) are also formed above the Sura facility. These perturbations can be due to the plasma density modulation by an artificial acoustic-gravity wave with a period of 10.6 m, which was formed by the heat source inside a large-scale cavity with low plasma density; there is generation of the electron density irregularities for the electrons with ΔNe/Ne ≈ 3% in the form of layers having the sizes 10-12 km along and about 24 km across the geomagnetic field, which are found both below and above the F2-layer maximum. The mechanisms of the formation of these plasma structures are discussed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22599949-experimental-investigation-effect-plasma-jet-triggered-discharge-process-gas-switch','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22599949-experimental-investigation-effect-plasma-jet-triggered-discharge-process-gas-switch">Experimental investigation on the effect of plasma jet in the triggered discharge process of a gas switch</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Tie, W., E-mail: twh.110.666@163.com, E-mail: 84470220@qq.com; Xi'an Jiaotong University, Xi'an 710049; Liu, S. The temporal and spatial evolution of a plasma jet generated by a spark discharge was observed. The electron temperature and density were obtained under different time and gas pressures by optical emission spectroscopy. Moreover, the discharge process of the plasma-jet triggered gas switch was recorded and analyzed at the lowest working coefficient. The results showed that the plasma jet moved forward in a bullet mode, and the advancing velocity increased with the decrease of pressure, and decreased with time growing. At initial time, the maximum velocity of a plasma jet could reach 3.68 × 10{sup 6 }cm/s. The electron temperature decreased from 2.0 eVmore » to 1.3 eV, and the electron density increased from 3.1 × 10{sup 15}/cm{sup 3} to 6.3 × 10{sup 15}/cm{sup 3} at the initial moment as the gas pressure increases from 0.1 MPa to 0.32 MPa. For a two-gap gas switch, the discharge performances were more depended on the second discharge spark gap (gap 2). Because plasma jet promoted the discharge in Gap 2, the gas switch operating in mode II had better triggered discharge characteristics. In the discharge process, the plasma-jet triggering had the effect of non-penetrating inducing, which not only provided initial electrons for reducing statistical lag but also enhanced the local electric field. The discharge was initiated and accelerated from electron avalanche to streamer. Therefore, a fast discharge was occurred in the gas switch.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19860040328&hterms=SMM&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3DSMM','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19860040328&hterms=SMM&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3DSMM">Multiwavelength analysis of a well observed flare from SMM. [Solar Maximum Mission</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Macneice, P.; Pallavicini, R.; Mason, H. E.; Simnett, G. M.; Antonucci, E.; Shine, R. A.; Dennis, B. R. 1985-01-01 Observations of an M 1.4 flare which began at 17:00 UT on November 12, 1980, are presented and analyzed. Ground based H-alpha and magnetogram data have been combined with EUV, soft and hard X-ray observations made with instruments on-board the Solar Maximum Mission satellite. The preflare phase was marked by a gradual brightening of the flare site in O v and the disappearance of an H-alpha filament. Filament ejecta were seen in O v moving southward at a speed of about 60 km/s, before the impulsive phase. The flare loop footpoints brightened in H-alpha and the Ca XIX resonance line broadened dramatically 2 min before the impulsive phase. Nonthermal hard X-ray emission was detected from the loop footpoints during the impulsive phase, while during the same period blue-shifts corresponding to upflows of 200-250 km/s were seen in Ca XIX. Evidence was found for energy deposition in both the chromosphere and corona at a number of stages during the flare. Two widely studied mechanisms for the production of the high temperature soft X-ray flare plasma in the corona are considered, i.e. chromospheric evaporation, and a model in which the heating and transfer of material occurs between flux tubes during reconnection. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AGUFMSH51A2437F','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AGUFMSH51A2437F">Solar Corona Simulation Model With Positivity-preserving Property</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Feng, X. S. 2015-12-01 Positivity-preserving is one of crucial problems in solar corona simulation. In such numerical simulation of low plasma β region, keeping density and pressure is a first of all matter to obtain physical sound solution. In the present paper, we utilize the maximum-principle-preserving flux limiting technique to develop a class of second order positivity-preserving Godunov finite volume HLL methods for the solar wind plasma MHD equations. Based on the underlying first order building block of positivity preserving Lax-Friedrichs, our schemes, under the constrained transport (CT) and generalized Lagrange multiplier (GLM) framework, can achieve high order accuracy, a discrete divergence-free condition and positivity of the numerical solution simultaneously without extra CFL constraints. Numerical results in four Carrington rotation during the declining, rising, minimum and maximum solar activity phases are provided to demonstrate the performance of modeling small plasma beta with positivity-preserving property of the proposed method. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/21532162-territorial-characteristics-low-frequency-electrostatic-fluctuations-simple-magnetized-torus','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/21532162-territorial-characteristics-low-frequency-electrostatic-fluctuations-simple-magnetized-torus">Territorial characteristics of low frequency electrostatic fluctuations in a simple magnetized torus</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Kaur, R.; Singh, R.; Sarada Sree, A. 2011-01-15 This paper presents an experimental investigation of turbulence in simple toroidal plasma devices without rotational transform. It is argued that Rayleigh-Taylor (flute interchange) mode may be one of the source mechanisms for the observed turbulence but is not sufficient to explain its observed global characteristics. Taking BETA device as an example, we show that pure Rayleigh-Taylor mode cannot explain (i) the observation of mode maximum at the location other than where density scale length is minimum, (ii) the comparable value of amplitude level of fluctuations in good curvature region, and (iii) the decrease in the mode amplitude with increasing magneticmore » field. Investigations have revealed that there exists not only poloidal plasma flow but also that it is sheared. Including this effect explains the first observation. However, modification brought about by velocity shear in the Rayleigh-Taylor mode still does not explain our second and third observations. We have taken an approach that since Rayleigh-Taylor is not excited in a good curvature region, it cannot be the source of turbulence there. Nor is it defensible to say that turbulence born in a bad curvature region is carried over through ExB rotation to the good curvature region. Consequently, we have invoked cross-field Simon-Hoh instability for this region. Experimental evidence supporting our proposal is presented. This paper concludes that toroidal devices have simultaneous existence of different self-consistent sources of turbulence in different regions of the device.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28933336','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28933336">Bioavailability of oxycodone after administration of a new prolonged-release once-daily tablet formulation in healthy subjects, in comparison to an established twice-daily tablet .</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Scheidel, Bernhard; Maritz, Martina A; Gschwind, Yves J; Steigerwald, Kerstin; Guth, Volker; Kovacs, Peter; Rey, Helene 2017-11-01 To evaluate and to compare the bioavailability, the influence of food intake on the bioavailability, and the safety and tolerability of a newly-developed oxycodone once-daily (OOD) prolonged-release tablet with an established oxycodone twice-daily (OTD) prolonged-release tablet after single-dose administration under fasting or fed conditions as well as after multiple-dose administration. Three single-center, open-label, randomized, balanced, two-treatment, two-period, two-sequence crossover studies were conducted. In each study, 36 healthy volunteers were randomized to receive 10 mg oxycodone daily as OOD (oxycodone HCL 10-mg PR tablets XL (Develco Pharma Schweiz AG, Pratteln, Switzerland); administration of 1 tablet in the morning) or as OTD (reference formulation: oxygesic 5-mg tablets (Mundipharma GmbH, Limburg an der Lahn, Germany); administration of 1 tablet in the morning and 1 tablet in the evening). Tablets were administered once daily or twice daily under fasting conditions (study 1) or under fed conditions (study 2) as well as after multiple-dose administration (study 3). A sufficient number of blood samples were taken for describing plasma profiles and for calculation of pharmacokinetic parameters. Plasma concentrations of oxycodone were determined by LC-MS/MS. Safety and tolerability were monitored and assessed in all three studies. Plasma profiles of OOD reveal sustained concentrations of oxycodone over the complete dosing interval of 24 hours. In comparison to the OTD reference formulation, the OOD test formulation showed a slightly slower increase of concentrations within the absorption phase and similar plasma concentrations at the maximum and at the end of the dosing interval (24 hours). Extent of bioavailability (AUC), maximum plasma concentrations (Cmax), and plasma concentrations at the end of the dosing interval (Cτ,ss,24h) of OOD could be classified as comparable to OTD considering 90% confidence intervals (CIs) and acceptance limits of 80.00 - 125.00%. Bioavailability of OOD was not influenced by concomitant food intake. OOD and OTD were generally well tolerated, a difference between the two products could not be observed. The new 10-mg OOD formulation provides sustained oxycodone plasma concentrations over the dosing interval of 24 hours and is suitable for once-daily administration. Bioavailability of OOD could be classified as comparable to the twice-daily administration of the OTD reference formulation. The new formulation widens and optimizes the range of strong opioid drug products in patient-centered therapy of chronic pain with simplified dosing and better compliance. . </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011ApJ...726L..13A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011ApJ...726L..13A">Location of γ-ray Flare Emission in the Jet of the BL Lacertae Object OJ287 More than 14 pc from the Central Engine</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Agudo, Iván; Jorstad, Svetlana G.; Marscher, Alan P.; Larionov, Valeri M.; Gómez, José L.; Lähteenmäki, Anne; Gurwell, Mark; Smith, Paul S.; Wiesemeyer, Helmut; Thum, Clemens; Heidt, Jochen; Blinov, Dmitriy A.; D'Arcangelo, Francesca D.; Hagen-Thorn, Vladimir A.; Morozova, Daria A.; Nieppola, Elina; Roca-Sogorb, Mar; Schmidt, Gary D.; Taylor, Brian; Tornikoski, Merja; Troitsky, Ivan S. 2011-01-01 We combine time-dependent multi-waveband flux and linear polarization observations with submilliarcsecond-scale polarimetric images at λ = 7 mm of the BL Lacertae type blazar OJ287 to locate the γ-ray emission in prominent flares in the jet of the source >14 pc from the central engine. We demonstrate a highly significant correlation between the strongest γ-ray and millimeter-wave flares through Monte Carlo simulations. The two reported γ-ray peaks occurred near the beginning of two major millimeter-wave outbursts, each of which is associated with a linear polarization maximum at millimeter wavelengths. Our very long baseline array observations indicate that the two millimeter-wave flares originated in the second of two features in the jet that are separated by >14 pc. The simultaneity of the peak of the higher-amplitude γ-ray flare and the maximum in polarization of the second jet feature implies that the γ-ray and millimeter-wave flares are cospatial and occur >14 pc from the central engine. We also associate two optical flares, accompanied by sharp polarization peaks, with the two γ-ray events. The multi-waveband behavior is most easily explained if the γ-rays arise from synchrotron self-Compton scattering of optical photons from the flares. We propose that flares are triggered by interaction of moving plasma blobs with a standing shock. The γ-ray and optical emission is quenched by inverse Compton losses as synchrotron photons from the newly shocked plasma cross the emission region. The millimeter-wave polarization is high at the onset of a flare, but decreases as the electrons emitting at these wavelengths penetrate less polarized regions. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/21560583-location-gamma-ray-flare-emission-jet-bl-lacertae-object-oj287-more-than-pc-from-central-engine','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/21560583-location-gamma-ray-flare-emission-jet-bl-lacertae-object-oj287-more-than-pc-from-central-engine">LOCATION OF {gamma}-RAY FLARE EMISSION IN THE JET OF THE BL LACERTAE OBJECT OJ287 MORE THAN 14 pc FROM THE CENTRAL ENGINE</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Agudo, Ivan; Jorstad, Svetlana G.; Marscher, Alan P. We combine time-dependent multi-waveband flux and linear polarization observations with submilliarcsecond-scale polarimetric images at {lambda} = 7 mm of the BL Lacertae type blazar OJ287 to locate the {gamma}-ray emission in prominent flares in the jet of the source >14 pc from the central engine. We demonstrate a highly significant correlation between the strongest {gamma}-ray and millimeter-wave flares through Monte Carlo simulations. The two reported {gamma}-ray peaks occurred near the beginning of two major millimeter-wave outbursts, each of which is associated with a linear polarization maximum at millimeter wavelengths. Our very long baseline array observations indicate that the two millimeter-wavemore » flares originated in the second of two features in the jet that are separated by >14 pc. The simultaneity of the peak of the higher-amplitude {gamma}-ray flare and the maximum in polarization of the second jet feature implies that the {gamma}-ray and millimeter-wave flares are cospatial and occur >14 pc from the central engine. We also associate two optical flares, accompanied by sharp polarization peaks, with the two {gamma}-ray events. The multi-waveband behavior is most easily explained if the {gamma}-rays arise from synchrotron self-Compton scattering of optical photons from the flares. We propose that flares are triggered by interaction of moving plasma blobs with a standing shock. The {gamma}-ray and optical emission is quenched by inverse Compton losses as synchrotron photons from the newly shocked plasma cross the emission region. The millimeter-wave polarization is high at the onset of a flare, but decreases as the electrons emitting at these wavelengths penetrate less polarized regions.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16051960','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16051960">Phase I safety, pharmacokinetic, and pharmacodynamic study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced cancer.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Hoekstra, Ronald; de Vos, Filip Y F L; Eskens, Ferry A L M; Gietema, Jourik A; van der Gaast, Ate; Groen, Harry J M; Knight, Raymond A; Carr, Robert A; Humerickhouse, Rod A; Verweij, Jaap; de Vries, Elisabeth G E 2005-08-01 ABT-510 is an angiogenesis inhibitor derived from thrombospondin-1, a naturally occurring inhibitor of angiogenesis. We investigated ABT-510, which was administered subcutaneously in patients with advanced solid malignancies, to assess safety, pharmacokinetics, and serum markers of angiogenesis. ABT-510 was administered subcutaneously as a continuous infusion (100 mg/24 h) and bolus injections (100, 200, and 260 mg once daily; 50 and 100 mg twice daily) in 28-day cycles. Thirty-nine patients received a total of 144 treatment cycles. Administration by continuous infusion was hampered by the onset of painful skin infiltrates at the injection site. In the bolus injection regimens, the most common toxicities observed were mild injection-site reactions and fatigue. Maximum-tolerated dose was not defined, but 260 mg was defined as the maximum clinically practical dose. ABT-510 pharmacokinetics were linear across the dosage ranges tested, and the potential therapeutic threshold (plasma concentrations > 100 ng/mL > 3 h/d) was achieved with all dose regimens. Median serum basic fibroblast growth factor (bFGF) levels decreased from 14.1 pg/mL (range, 0.5 to 77.7 pg/mL) at baseline to 3.2 pg/mL (range, 0.2 to 29.4 pg/mL) after 56 days of treatment (P = .003). No correlations with time on study or ABT-510 dose or exposure were observed for individual changes in bFGF. Stable disease lasting for six cycles or more was seen in six patients. ABT-510 demonstrated a favorable toxicity profile and linear and time-independent pharmacokinetics with biologically relevant plasma concentrations. The significant number of patients with prolonged stable disease and the convenient method of dosing merit further studies with this angiogenesis inhibitor. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/21428862-narrow-energy-spread-protons-ions-from-high-intensity-high-contrast-laser-solid-target-interactions','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/21428862-narrow-energy-spread-protons-ions-from-high-intensity-high-contrast-laser-solid-target-interactions">Narrow Energy Spread Protons and Ions from High-Intensity, High-Contrast Laser Solid Target Interactions</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Dollar, Franklin; Matsuoka, Takeshi; McGuffey, Christopher 2010-11-04 Recent simulations show that an idealized, high intensity, short pulse laser can generate quasi-monoenergetic proton beams with energies over 100 MeV in an interaction with a thin film. However, most short pulse laser facilities with sufficient intensity have difficulty controlling the nanosecond and picosecond contrast necessary to realize such a regime. Experiments were performed to investigate proton and ion acceleration from a high contrast, short pulse laser by employing dual plasma mirrors along with a deformable mirror at the HERCULES laser facility at the Center for Ultrafast Optical Sciences, University of Michigan. Plasma mirrors were characterized, allowing a 50% throughputmore » with an intensity contrast increase of 105. The focal spot quality was also exceptional, showing a 1.1 micron full width at half maximum (FWHM) focal diameter. Experiments were done using temporally cleaned 30 TW, 32 fs pulses to achieve an intensity of up to 10{sup 21} Wcm{sup -2} on Si{sub 3}N{sub 4} and Mylar targets with thicknesses ranging 50 nm to 13 microns. Proton beams with energy spreads below 2 MeV were observed from all thicknesses, peaking with energies up to 10.3 MeV and an energy spread of 0.8 MeV. Similar narrow energy spreads were observed for oxygen, nitrogen, and carbon at the silicon nitride thickness of 50 nm with energies up to 24 MeV with an energy spread of 3 MeV, whereas the energy spread is greatly increased at a larger thickness. Maximum energies were confirmed with CR39 track detectors, while a Thomson ion spectrometer was used to gauge the monoenergetic nature of the beam.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3837917','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3837917">Pharmacokinetics of Hydroxymethylnitrofurazone, a Promising New Prodrug for Chagas' Disease Treatment</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Serafim, Eliana Ometto Pavan; Silva, Antonio Távora de Albuquerque e; Moreno, Andréia de Haro; Vizioli, Ednir de Oliveira; Ferreira, Elizabeth Igne; Ribeiro, Maria Lucia 2013-01-01 Hydroxymethylnitrofurazone (NFOH) is a trypanocidal prodrug of nitrofurazone (NF), devoid of mutagenic toxicity. The purpose of this work was to study the chemical conversion of NFOH into NF in sodium acetate buffer (pH 1.2 and 7.4) and in human plasma and to determine preclinical pharmacokinetic parameters in rats. At pH 1.2, the NFOH was totally transformed into NF, the parent drug, after 48 h, while at pH 7.4, after the same period, the hydrolysis rate was 20%. In human plasma, 50% of NFOH was hydrolyzed after 24 h. In the investigation of kinetic disposition, the concentration of drug in serum versus time curve was used to calculate the pharmacokinetic parameters after a single-dose regimen. NFOH showed a time to maximum concentration of drug in serum (Tmax) as 1 h, suggesting faster absorption than NF (4 h). The most important results observed were the volume of distribution (V) of NFOH through the tissues, which showed a rate that is 20-fold higher (337.5 liters/kg of body weight) than that of NF (17.64 liters/kg), and the concentration of NF obtained by in vivo metabolism of NFOH, which was about four times lower (maximum concentration of drug in serum [Cmax] = 0.83 μg/ml; area under the concentration-time curve from 0 to 12 h [AUC0–12] = 5.683 μg/ml · h) than observed for administered NF (Cmax = 2.78 μg/ml; AUC0–12 = 54.49 μg/ml · h). These findings can explain the superior activity and lower toxicity of the prodrug NFOH in relation to its parent drug and confirm NFOH as a promising anti-Chagas' disease drug candidate. PMID:24080661 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27805928','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27805928">Development of a Simple and Rapid Method to Measure the Free Fraction of Tacrolimus in Plasma Using Ultrafiltration and LC-MS/MS.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Stienstra, Nicolaas A; Sikma, Maaike A; van Dapperen, Anouk L; de Lange, Dylan W; van Maarseveen, Erik M 2016-12-01 Tacrolimus is an immunosuppressant mainly used in the prophylaxis of solid organ transplant rejection. Therapeutic drug monitoring of tacrolimus is essential for avoiding toxicity related to overexposure and transplant rejection from underexposure. Previous studies suggest that unbound tacrolimus concentrations in the plasma may serve as a better predictor of tacrolimus-associated nephrotoxicity and neurotoxicity compared to tacrolimus concentration in whole blood. Monitoring the plasma concentrations of unbound tacrolimus might be of interest in preventing tacrolimus-related toxicity. Therefore, the aim was to develop a method for the measurement of total and unbound tacrolimus concentrations in plasma. The sample preparation for the determination of the plasma concentrations of unbound tacrolimus consisted of an easy-to-use ultrafiltration method followed by solid-phase extraction. To determine the total concentration of tacrolimus in plasma, a simple method based on protein precipitation was developed. The extracts were injected into a Thermo Scientific HyPurity C18 column using gradient elution. The analytes were detected by liquid chromatography-tandem mass spectrometry with positive ionization. The method was validated over a linear range of 1.00-200 ng/L for unbound tacrolimus concentrations in plasma and 100-3200 ng/L for total plasma concentrations. The lower limit of quantification was 1.00 ng/L in ultrafiltrate and 100 ng/L in plasma. The inaccuracy and imprecision for the determination of unbound tacrolimus concentrations in ultrafiltrate and plasma showed a maximum coefficients of variation (CV) of 11.7% and a maximum bias of 3.8%. A rapid and easy method based on ultrafiltration and liquid chromatography-tandem mass spectrometry was established to measure the total and unbound tacrolimus concentrations in plasma. This method can facilitate further investigations on the relationship between plasma concentrations of unbound tacrolimus and clinical outcomes in transplant recipients. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20040087974&hterms=blue+light&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dblue%2Blight','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20040087974&hterms=blue+light&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dblue%2Blight">The plasma membrane-associated NADH oxidase of spinach leaves responds to blue light</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Morre, D. James; Penel, Claude; Greppin, Hubert; Morre, Dorothy M. 2002-01-01 The plasma membrane-associated NADH oxidase (NOX) of spinach leaf disks is characterized by oscillations in activity with a regular period length of ca. 24 min. Within a single population of plants exposed to light at the same time, NOX activities of all plants function synchronously. Exposure of plants transferred from darkness to blue light (495 nm, 2 min, 50 micromoles m-2 s-1) resulted in a complex response pattern but with a new maximum in the rate of NOX activity 36 (24+12) min after illumination and then with maxima in the rate of NOX activity every 24 min thereafter. Transient maxima in NOX activity were observed as well after 9.3 + /- 1.4 and 20.7 +/- 2.1 min. The blue light response differed from the response to red (650 nm, 10 min, 50 micromoles m-2 s-1) or white light where activity maxima were initiated 12 min after the light exposure followed by maxima every 24 min thereafter. Green or yellow light was ineffective. The light response was independent of the time in the 24-min NOX cycle when the light was given. The net effects of blue and red light were ultimately the same with a new maximum in the rate of NOX activity at 12+24=36 min (and every 24 min thereafter), but the mechanisms appear to be distinct. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li class="active">20</li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_21" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li class="active">21</li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="401"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3507050','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3507050">Comparison of Oogenesis and Sex Steroid Profiles between Twice and Once Annually Spawning of Rainbow Trout Females (Oncorhynchus mykiss)</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Estay, Francisco; Colihueque, Nelson; Araneda, Cristian 2012-01-01 This study compares the gonadosomatic index (GSI), oocyte growth (OG), gonadal histology, and plasma level concentrations of sex hormones (estradiol-17β (E2) and vitellogenin (V)) of twice-spawning (T-SP) and once-spawning (O-SP) females of rainbow trout throughout the additional and the normal reproductive cycle, respectively. In T-SP, the GSI values rapidly increase from May to November, in contrast to O-SP, which showed low and constant GSI values (1.19 to 14.5 and 1.19 to 0.63, resp.). T-SP exhibited a marked increase of OG in the same period, reaching a maximum diameter of 4,900 ± 141.42 μm, in contrast to O-SP, which presented a slow OG. The gonadal histology of T-SP agreed with the general pattern of ovogenesis observed for O-SP (vitellogenesis, ovulation, and recrudescence); however, this process was nonsynchronous between the two breeder groups. Plasma steroid levels showed significant variation during oogenesis, which agreed with the GSI, OG, and gonadal histology patterns. The level of E2 increased to a maximum value of 26.2 ng/mL and 36.0 ng/mL in O-SP and T-SP, respectively, one or two months before the spawning event where vitellogenesis was fully active. The V concentrations followed a pattern similar to those of E2. PMID:23213308 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22304059-transport-ion-beam-annular-magnetically-expanding-helicon-double-layer-thruster','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22304059-transport-ion-beam-annular-magnetically-expanding-helicon-double-layer-thruster">Transport of ion beam in an annular magnetically expanding helicon double layer thruster</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Zhang, Yunchao, E-mail: yunchao.zhang@anu.edu.au; Charles, Christine; Boswell, Rod 2014-06-15 An ion beam generated by an annular double layer has been measured in a helicon thruster, which sustains a magnetised low-pressure (5.0 × 10{sup −4} Torr) argon plasma at a constant radio-frequency (13.56 MHz) power of 300 W. After the ion beam exits the annular structure, it merges into a solid centrally peaked structure in the diffusion chamber. As the annular ion beam moves towards the inner region in the diffusion chamber, a reversed-cone plasma wake (with a half opening angle of about 30°) is formed. This process is verified by measuring both the radial and axial distributions of the beam potential and beammore » current. The beam potential changes from a two-peak radial profile (maximum value ∼ 30 V, minimum value ∼ 22.5 V) to a flat (∼28 V) along the axial direction; similarly, the beam current changes from a two-peak to one-peak radial profile and the maximum value decreases by half. The inward cross-magnetic-field motion of the beam ions is caused by a divergent electric field in the source. Cross-field diffusion of electrons is also observed in the inner plume and is determined as being of non-ambipolar origin.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JAP...119t5705L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JAP...119t5705L">Limitations of threshold voltage engineering of AlGaN/GaN heterostructures by dielectric interface charge density and manipulation by oxygen plasma surface treatments</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Lükens, G.; Yacoub, H.; Kalisch, H.; Vescan, A. 2016-05-01 The interface charge density between the gate dielectric and an AlGaN/GaN heterostructure has a significant impact on the absolute value and stability of the threshold voltage Vth of metal-insulator-semiconductor (MIS) heterostructure field effect transistor. It is shown that a dry-etching step (as typically necessary for normally off devices engineered by gate-recessing) before the Al2O3 gate dielectric deposition introduces a high positive interface charge density. Its origin is most likely donor-type trap states shifting Vth to large negative values, which is detrimental for normally off devices. We investigate the influence of oxygen plasma annealing techniques of the dry-etched AlGaN/GaN surface by capacitance-voltage measurements and demonstrate that the positive interface charge density can be effectively compensated. Furthermore, only a low Vth hysteresis is observable making this approach suitable for threshold voltage engineering. Analysis of the electrostatics in the investigated MIS structures reveals that the maximum Vth shift to positive voltages achievable is fundamentally limited by the onset of accumulation of holes at the dielectric/barrier interface. In the case of the Al2O3/Al0.26Ga0.74N/GaN material system, this maximum threshold voltage shift is limited to 2.3 V. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26588924','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26588924">Safety and tolerability of ibrutinib monotherapy in Japanese patients with relapsed/refractory B cell malignancies.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Tobinai, Kensei; Ogura, Michinori; Ishizawa, Kenichi; Suzuki, Tatsuya; Munakata, Wataru; Uchida, Toshiki; Aoki, Tomohiro; Morishita, Takanobu; Ushijima, Yoko; Takahara, Satoko 2016-01-01 In this phase I dose-escalation study we evaluated the safety, tolerability, pharmacokinetics, and antitumor activity of ibrutinib, an oral covalent inhibitor of Bruton's tyrosine kinase (BTK, in Japanese patients with relapsed/refractory B cell malignancies (RRBCM). Fifteen patients aged 42-78 years were enrolled to one of three cohorts. Cohort 1 (n = 3) consisted of two phases, a single-dose (140 and 280 mg) phase and a multiple-dose (420 mg) phase of ibrutinib; cohort 2 (n = 6) included multiple doses of ibrutinib 560 mg; and cohort 3 (n = 6) included only patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) dosed at ibrutinib 420 mg. One patient (CLL/SLL cohort) experienced grade 3 pneumonia and sepsis, which were considered dose-limiting toxicities. No deaths were reported. The most common (≥ 20% patients) adverse events were neutropenia, anemia, nasopharyngitis, increased bilirubin, and rash. Dose-dependent increase in maximum plasma concentration and area under the concentration from 0 to the last quantifiable time was observed, while time to reach maximum plasma concentration and elimination half-life was similar between doses. The overall response rate was 73.3% (11/15) for all cohorts combined. Overall, ibrutinib (420 and 560 mg) was tolerable with acceptable safety profiles and effective for Japanese patients with RRBCM including CLL/SLL. NCT01704963. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018ApSS..443..184K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018ApSS..443..184K">As-pyrolyzed sugarcane bagasse possessing exotic field emission properties</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Krishnia, Lucky; Yadav, Brajesh S.; Palnitkar, Umesh; Satyam, P. V.; Gupta, Bipin Kumar; Koratkar, Nikhil A.; Tyagi, Pawan K. 2018-06-01 The present study aims to demonstrate the application of sugarcane bagasse as an excellent field emitter. Field emission property of as-pyrolyzed sugarcane bagasse (p-SBg) before and after the plasma treatment has been investigated. It has been observed that electronic nature of p-SBg transformed from semiconducting to metallic after plasma treatment. Maximum current and turn-on field defined at 10 μA/cm2 was found to be 800 μA/cm2 and 2.2 V/μm for as-pyrolyzed sugarcane bagasse (p-SBg) and 25 μA/cm2 and 8.4 V/μm for H2-plasma treated p-SBg. These values are found to be better than the reported values for graphene and activated carbon. In this report, pyrolysis of bagasse has been carried in a thermal chemical vapor deposition (Th-CVD) system in inert argon atmosphere. Scanning electron microscopy (SEM), X-ray Diffraction (XRD), High-resolution transmission electron microscopy (HRTEM) and X-ray photoelectron spectroscopy (XPS) have been used to study the structure of both pre and post plasma-treated p-SBg bagasse's sample. HRTEM study reveals that carbonaceous structures such as 3D-nanographene oxide (3D-NGO), graphite nanodots (GNDs), carbon nanotubes (CNTs), and carbon onions are present in both pre-treated and plasma-treated p-SBg. Hence, we envision that the performed study will be a forwarding step to facilitate the application of p-SBg in display devices. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19730280','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19730280">Pharmacokinetic/pharmacodynamic modeling of psychomotor impairment induced by oral clonazepam in healthy volunteers.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> dos Santos, Fábio Monteiro; Gonçalves, José Carlos Saraiva; Caminha, Ricardo; da Silveira, Gabriel Estolano; Neves, Claúdia Silvana de Miranda; Gram, Karla Regina da Silva; Ferreira, Carla Teixeira; Jacqmin, Philippe; Noël, François 2009-10-01 This study was undertaken to model the relationship between clonazepam plasma concentrations and a central nervous system adverse effect (impairment of the psychomotor performance) following the oral administration of immediate-release tablets of clonazepam in healthy volunteers. Such a (P)pharmacokinetic/(P)pharmacodynamic (PK/PD) study is important to interpret properly the consequences of determined levels of plasma concentrations of psychoactive therapeutic drugs reported to be involved in road-traffic accidents. Twenty-three male subjects received a single oral dose of 4 mg clonazepam. Plasma concentration, determined by on-line solid phase extraction coupled with high-performance liquid chromatography tandem mass spectrometry, and psychomotor performance, quantified through the Digit Symbol Substitution Test, were monitored for 72 hours. A 2-compartment open model with first order absorption and lag-time better fitted the plasma clonazepam concentrations. Clonazepam decreased the psychomotor performance by 72 +/- 3.7% (observed maximum effect), 1.5 to 4 hours (25th-75th percentile) after drug administration. A simultaneous population PK/PD model based on a sigmoid Emax model with time-dependent tolerance described well the time course of effect. Such acute tolerance could minimize the risk of accident as a result of impairment of motor skill after a single dose of clonazepam. However, an individual analysis of the data revealed a great interindividual variation in the relationship between clonazepam effect and plasma concentration, indicating that the phenomenon of acute tolerance can be predicted at a population, but not individual, level. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018PhPl...25d2903N','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018PhPl...25d2903N">Magnetic reconnection in the low solar chromosphere with a more realistic radiative cooling model</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Ni, Lei; Lukin, Vyacheslav S.; Murphy, Nicholas A.; Lin, Jun 2018-04-01 Magnetic reconnection is the most likely mechanism responsible for the high temperature events that are observed in strongly magnetized locations around the temperature minimum in the low solar chromosphere. This work improves upon our previous work [Ni et al., Astrophys. J. 852, 95 (2018)] by using a more realistic radiative cooling model computed from the OPACITY project and the CHIANTI database. We find that the rate of ionization of the neutral component of the plasma is still faster than recombination within the current sheet region. For low β plasmas, the ionized and neutral fluid flows are well-coupled throughout the reconnection region resembling the single-fluid Sweet-Parker model dynamics. Decoupling of the ion and neutral inflows appears in the higher β case with β0=1.46 , which leads to a reconnection rate about three times faster than the rate predicted by the Sweet-Parker model. In all cases, the plasma temperature increases with time inside the current sheet, and the maximum value is above 2 ×104 K when the reconnection magnetic field strength is greater than 500 G. While the more realistic radiative cooling model does not result in qualitative changes of the characteristics of magnetic reconnection, it is necessary for studying the variations of the plasma temperature and ionization fraction inside current sheets in strongly magnetized regions of the low solar atmosphere. It is also important for studying energy conversion during the magnetic reconnection process when the hydrogen-dominated plasma approaches full ionization. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018SpWea..16..321A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018SpWea..16..321A">Midlatitude Plasma Bubbles Over China and Adjacent Areas During a Magnetic Storm on 8 September 2017</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Aa, Ercha; Huang, Wengeng; Liu, Siqing; Ridley, Aaron; Zou, Shasha; Shi, Liqin; Chen, Yanhong; Shen, Hua; Yuan, Tianjiao; Li, Jianyong; Wang, Tan 2018-03-01 This paper presents observations of postsunset super plasma bubbles over China and adjacent areas during the second main phase of a storm on 8 September 2017. The signatures of the plasma bubbles can be seen or deduced from (1) deep field-aligned total electron content depletions embedded in regional ionospheric maps derived from dense Global Navigation Satellite System networks, (2) significant equatorial and midlatitudinal plasma bite-outs in electron density measurements on board Swarm satellites, and (3) enhancements of ionosonde virtual height and scintillation in local evening associated with strong southward interplanetary magnetic field. The bubbles/depletions covered a broad area mainly within 20°-45°N and 80°-110°E with bifurcated structures and persisted for nearly 5 hr (˜13-18 UT). One prominent feature is that the bubbles extended remarkably along the magnetic field lines in the form of depleted flux tubes, reaching up to midlatitude of around 50°N (magnetic latitude: 45.5°N) that maps to an altitude of 6,600 km over the magnetic equator. The maximum upward drift speed of the bubbles over the magnetic equator was about 700 m/s and gradually decreased with altitude and time. The possible triggering mechanism of the plasma bubbles was estimated to be storm time eastward prompt penetration electric field, while the traveling ionospheric disturbance could play a role in facilitating the latitudinal extension of the depletions. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22305928-electron-heating-enhancement-frequency-chirped-laser-pulses','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22305928-electron-heating-enhancement-frequency-chirped-laser-pulses">Electron heating enhancement by frequency-chirped laser pulses</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Yazdani, E.; Afarideh, H., E-mail: hafarideh@aut.ac.ir; Sadighi-Bonabi, R., E-mail: Sadighi@sharif.ir 2014-09-14 Propagation of a chirped laser pulse with a circular polarization through an uprising plasma density profile is studied by using 1D-3V particle-in-cell simulation. The laser penetration depth is increased in an overdense plasma compared to an unchirped pulse. The induced transparency due to the laser frequency chirp results in an enhanced heating of hot electrons as well as increased maximum longitudinal electrostatic field at the back side of the solid target, which is very essential in target normal sheath acceleration regime of proton acceleration. For an applied chirp parameter between 0.008 and 0.01, the maximum amount of the electrostatic fieldmore » is improved by a factor of 2. Furthermore, it is noticed that for a chirped laser pulse with a₀=5, because of increasing the plasma transparency length, the laser pulse can penetrate up to about n{sub e}≈6n{sub c}, where n{sub c} is plasma critical density. It shows 63% increase in the effective critical density compared to the relativistic induced transparency regime for an unchirped condition.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016ApPhL.109o2106H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016ApPhL.109o2106H">Normally-off p-GaN/AlGaN/GaN high electron mobility transistors using hydrogen plasma treatment</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Hao, Ronghui; Fu, Kai; Yu, Guohao; Li, Weiyi; Yuan, Jie; Song, Liang; Zhang, Zhili; Sun, Shichuang; Li, Xiajun; Cai, Yong; Zhang, Xinping; Zhang, Baoshun 2016-10-01 In this letter, we report a method by introducing hydrogen plasma treatment to realize normally-off p-GaN/AlGaN/GaN HEMT devices. Instead of using etching technology, hydrogen plasma was adopted to compensate holes in the p-GaN above the two dimensional electron gas (2DEG) channel to release electrons in the 2DEG channel and form high-resistivity area to reduce leakage current and increase gate control capability. The fabricated p-GaN/AlGaN/GaN HEMT exhibits normally-off operation with a threshold voltage of 1.75 V, a subthreshold swing of 90 mV/dec, a maximum transconductance of 73.1 mS/mm, an ON/OFF ratio of 1 × 107, a breakdown voltage of 393 V, and a maximum drain current density of 188 mA/mm at a gate bias of 6 V. The comparison of the two processes of hydrogen plasma treatment and p-GaN etching has also been made in this work. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21493998','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21493998">Postprandial glucose response to selected tropical fruits in normal glucose-tolerant Nigerians.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Edo, A; Eregie, A; Adediran, O; Ohwovoriole, A; Ebengho, S 2011-01-01 The glycemic response to commonly eaten fruits in Nigeria has not been reported. Therefore, this study assessed the plasma glucose response to selected fruits in Nigeria. Ten normal glucose-tolerant subjects randomly consumed 50 g carbohydrate portions of three fruits: banana (Musa paradisiaca), pineapple (Ananus comosus), and pawpaw (Carica papaya), and a 50-g glucose load at 1-week intervals. Blood samples were collected in the fasting state and half-hourly over a 2-h period post-ingestion of the fruits or glucose. The samples were analyzed for plasma glucose concentrations. Plasma glucose responses were assessed by the peak plasma glucose concentration, maximum increase in plasma glucose, 2-h postprandial plasma glucose level, and incremental area under the glucose curve and glycemic index (GI). The results showed that the blood glucose response to these three fruits was similar in terms of their incremental areas under the glucose curve, maximum increase in plasma glucose, and glycemic indices (GIs). The 2-h postprandial plasma glucose level of banana was significantly higher than that of pineapple, P < 0.025. The mean ± SEM GI values were as follows: pawpaw; 86 ± 26.8%; banana, 75.1 ± 21.8%; pineapple, 64.5 ± 11.3%. The GI of glucose is taken as 100. The GI of pineapple was significantly lower than that of glucose (P < 0.05). Banana, pawpaw, and pineapple produced a similar postprandial glucose response. Measured portions of these fruits may be used as fruit exchanges with pineapple having the most favorable glycemic response. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014JPhD...47l5401Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014JPhD...47l5401Y">Flux of OH and O radicals onto a surface by an atmospheric-pressure helium plasma jet measured by laser-induced fluorescence</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Yonemori, Seiya; Ono, Ryo 2014-03-01 The atmospheric-pressure helium plasma jet is of emerging interest as a cutting-edge biomedical device for cancer treatment, wound healing and sterilization. Reactive oxygen species such as OH and O radicals are considered to be major factors in the application of biological plasma. In this study, density distribution, temporal behaviour and flux of OH and O radicals on a surface are measured using laser-induced fluorescence. A helium plasma jet is generated by applying pulsed high voltage of 8 kV with 10 kHz using a quartz tube with an inner diameter of 4 mm. To evaluate the relation between the surface condition and active species production, three surfaces are used: dry, wet and rat skin. When the helium flow rate is 1.5 l min-1, radial distribution of OH density on the rat skin surface shows a maximum density of 1.2 × 1013 cm-3 at the centre of the plasma-mediated area, while O atom density shows a maximum of 1.0 × 1015 cm-3 at 2.0 mm radius from the centre of the plasma-mediated area. Their densities in the effluent of the plasma jet are almost constant during the intervals of the discharge pulses because their lifetimes are longer than the pulse interval. Their density distribution depends on the helium flow rate and the surface humidity. With these results, OH and O production mechanisms in the plasma jet and their flux onto the surface are discussed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017PlST...19j5403A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017PlST...19j5403A">Directional power absorption in helicon plasma sources excited by a half-helix antenna</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Afsharmanesh, Mohsen; Habibi, Morteza 2017-10-01 This paper deals with the investigation of the power absorption in helicon plasma excited through a half-helix antenna driven at 13.56 {{MHz}}. The simulations were carried out by means of a code, HELIC. They were carried out by taking into account different inhomogeneous radial density profiles and for a wide range of plasma densities, from {10}11 {{{cm}}}-3 to {10}13 {{{cm}}}-3. The magnetic field was 200, 400, 600 and 1000 {{G}}. A three-parameter function was used for generating various density profiles with different volume gradients, edge gradients and density widths. The density profile had a large effect on the efficient Trivelpiece-Gould (TG) and helicon mode excitation and antenna coupling to the plasma. The fraction of power deposition via the TG mode was extremely dependent on the plasma density near the plasma boundary. Interestingly, the obtained efficient parallel helicon wavelength was close to the anticipated value for Gaussian radial density profile. Power deposition was considerably asymmetric when the \\tfrac{n}{{B}0} ratio was more than a specific value for a determined density width. The longitudinal power absorption was symmetric at approximately {n}0={10}11 {{{cm}}}-3, irrespective of the magnetic field supposed. The asymmetry became more pronounced when the plasma density was {10}12 {{{cm}}}-3. The ratio of density width to the magnetic field was an important parameter in the power coupling. At high magnetic fields, the maximum of the power absorption was reached at higher plasma density widths. There was at least one combination of the plasma density, magnetic field and density width for which the RF power deposition at both side of the tube reached its maximum value. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28500652','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28500652">Freeze-dried plasma enhances clot formation and inhibits fibrinolysis in the presence of tissue plasminogen activator similar to pooled liquid plasma.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Huebner, Benjamin R; Moore, Ernest E; Moore, Hunter B; Sauaia, Angela; Stettler, Gregory; Dzieciatkowska, Monika; Hansen, Kirk; Banerjee, Anirban; Silliman, Christopher C 2017-08-01 Systemic hyperfibrinolysis is an integral part of trauma-induced coagulopathy associated with uncontrolled bleeding. Recent data suggest that plasma-first resuscitation attenuates hyperfibrinolysis; however, the availability, transport, storage, and administration of plasma in austere environments remain challenging and have limited its use. Freeze-dried plasma (FDP) is a potential alternative due to ease of storage, longer shelf life, and efficient reconstitution. FDP potentially enhances clot formation and resists breakdown better than normal saline (NS) and albumin and similar to liquid plasma. Healthy volunteers underwent citrated blood draw followed by 50% dilution with NS, albumin, pooled plasma (PP), or pooled freeze-dried plasma (pFDP). Citrated native and tissue plasminogen activator (t-PA)-challenge (75 ng/mL) thrombelastography were done. Proteins in PP, pFDP, and albumin were analyzed by mass spectroscopy. pFDP and PP had superior clot-formation rates (angle) and clot strength (maximum amplitude) compared with NS and albumin in t-PA-challenge thrombelastographies (angle: pFDP, 67.9 degrees; PP, 67.8 degrees; NS, 40.6 degrees; albumin, 35.8 degrees; maximum amplitude: pFDP, 62.4 mm; PP, 63.5 mm; NS, 44.8 mm; albumin, 41.1 mm). NS and albumin dilution increased susceptibility to t-PA-induced hyperfibrinolysis compared with pFDP and PP (NS, 62.4%; albumin, 62.6%; PP, 8.5%; pFDP, 6.7%). pFDP was similar to PP in the attenuation of t-PA-induced fibrinolysis. Most proteins (97%) were conserved during the freeze-dry process, with higher levels in 12% of pFDP proteins compared with PP. pFDP enhances clot formation and attenuates hyperfibrinolysis better than NS and albumin and is a potential alternative to plasma resuscitation in the treatment of hemorrhagic shock. © 2017 AABB. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22482637-modified-quadrupole-mass-analyzer-rga-beam-plasma-research-forevacuum-pressure-range','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22482637-modified-quadrupole-mass-analyzer-rga-beam-plasma-research-forevacuum-pressure-range">Modified quadrupole mass analyzer RGA-100 for beam plasma research in forevacuum pressure range</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Zolotukhin, D. B.; Tyunkov, A. V.; Yushkov, Yu. G., E-mail: yuyushkov@gmail.com 2015-12-15 The industrial quadrupole RGA-100 residual gas analyzer was modified for the research of electron beam-generated plasma at forevacuum pressure range. The standard ionizer of the RGA-100 was replaced by three electrode extracting unit. We made the optimization of operation parameters in order to provide the maximum values of measured currents of any ion species. The modified analyzer was successfully tested with beam plasma of argon, nitrogen, oxygen, and hydrocarbons. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018PlST...20f5102L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018PlST...20f5102L">Influence of impurity seeding on the plasma radiation in the EAST tokamak</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Liping, DONG; Yanmin, DUAN; Kaiyun, CHEN; Xiuda, YANG; Ling, ZHANG; Feng, XU; Jingbo, CHEN; Songtao, MAO; Zhenwei, WU; Liqun, HU 2018-04-01 Plasma radiation characteristics in EAST argon (Ar) gas and neon (Ne) gas seeding experiments are studied. The radiation profiles reconstructed from the fast bolometer measurement data by tomography method are compared with the ones got from the simulation program based on corona model. And the simulation results coincide roughly with the experimental data. For Ar seeding discharges, the substantial enhanced radiations can be generally observed in the edge areas at normalized radius ρ pol∼0.7–0.9, while the enhanced regions are more outer for Ne seeding discharges. The influence of seeded Ar gas on the core radiation is related to the injected position. In discharges with LSN divertor configuration, the Ar ions can permeate into the core region more easily when being injected from the opposite upper divertor ports. In USN divertor configuration, the W impurity sputtered from the upper divertor target plates are observed to be an important contributor to the increase of the core radiation no matter impurity seeding from any ports. The maximum radiated power fractions f rad (P rad/P heat) about 60%–70% have been achieved in the recent EAST experimental campaign in 2015–2016. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1989JNuM..162..550P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1989JNuM..162..550P">In-situ observation of the chemical erosion of graphite in the scrape-off-layer of TEXTOR</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Philipps, V.; Vietzke, E.; Erdweg, M. 1989-04-01 A sniffer probe system has been used to investigate the chemical erosion during interaction of the TEXTOR scrape-off plasma with a pyrolytic graphite plate at temperatures up to 1400 °C. Floating potential conditions as well as 200 V bias has been applied at plasma ion fluxes of about 10 18ions/cm 2 sec.Methane formation was found to be 8 × 10 -3 CH 4/H and 1.5 × 10 -2 CD 4/D + for room temperature graphite and floating potential increasing by a factor of two at temperature around 500 °C. Biasing the graphite decreases the methane yield at room temperature and increase it in the maximum temperature range. CO formation due to chemical interaction of oxygen ions with the graphite reaches ratios between 3 and 6 × 10 -2 CO/D(H) near the limiter edge under normal TEXTOR scrape-off conditions and exceeds the chemical hydro-(deu-tero-carbon formation significantly. The results are discussed in view of the present status of hydro-(deutero-)carbon formation on graphite and carbon impurity observations made in fusion experiments. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016APS..DPPJO7004P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016APS..DPPJO7004P">Gyrokinetic GDC turbulence simulations: confirming a new instability regime in LAPD plasmas</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Pueschel, M. J.; Rossi, G.; Told, D.; Terry, P. W.; Jenko, F.; Carter, T. A. 2016-10-01 Recent high-beta experiments at the LArge Plasma Device have found significant parallel magnetic fluctuations in the region of large pressure gradients. Linear gyrokinetic simulations show the dominant instability at these radii to be the gradient-driven drift coupling (GDC) mode, a non-textbook mode driven by pressure gradients and destabilized by the coupling of ExB and grad-B∥ drifts. Unlike in previous studies, the large parallel extent of the device allows for finite-kz versions of this instability in addition to kz = 0 . The locations of maximum linear growth match very well with experimentally observed peaks of B∥ fluctuations. Local nonlinear simulations reproduce many features of the observations fairly well, with the exception of Bperp fluctuations, for which experimental profiles suggest a source unrelated to pressure gradients. In toto, the results presented here show that turbulence and transport in these experiments are driven by the GDC instability, that important characteristics of the linear instability carry over to nonlinear simulations, and - in the context of validation - that the gyrokinetic framework performs surprisingly well far outside its typical area of application, increasing confidence in its predictive abilities. Supported by U.S. DOE. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5066754','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5066754">Guaifenesin Pharmacokinetics Following Single‐Dose Oral Administration in Children Aged 2 to 17 Years</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Thompson, Gary A.; Solomon, Gail; Albrecht, Helmut H.; Reitberg, Donald P. 2016-01-01 Abstract This study characterized guaifenesin pharmacokinetics in children aged 2 to 17 years (n = 40) who received a single oral dose of guaifenesin (age‐based doses of 100‐400 mg) 2 hours after breakfast. Plasma samples were obtained before and for 8 hours after dosing and analyzed for guaifenesin using liquid chromatography‐tandem mass spectrometry. Pharmacokinetic parameters were estimated using noncompartmental methods, relationships with age were assessed using linear regression, and dose proportionality was assessed on 95% confidence intervals. Based on the upper dose recommended in the monograph (for both children and adolescents), area under the curve from time zero to infinity and maximum plasma concentration both increased with age. However, when comparing the upper dose for children aged 2 to 11 years with the lower dose for adolescents aged 12 to 17 years, similar systemic exposure was observed. As expected due to increasing body size, oral clearance (CLo) and terminal volume of distribution (Vz/F) increased with age. Due to a larger increase in Vz/F than CLo, an increase in terminal exponential half‐life was also observed. Allometric scaling indicated no maturation‐related changes in CLo and Vz/F. PMID:26632082 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017PlST...19d4002Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017PlST...19d4002Y">Experimental investigation of lift enhancement for flying wing aircraft using nanosecond DBD plasma actuators</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Yao, Junkai; Zhou, Danjie; He, Haibo; He, Chengjun; Shi, Zhiwei; Du, Hai 2017-04-01 The effects of the arrangement position and control parameters of nanosecond dielectric barrier discharge (NS-DBD) plasma actuators on lift enhancement for flying wing aircraft were investigated through wind tunnel experiments at a flow speed of 25 m s-1. The aerodynamic forces and moments were obtained by a six-component balance at angles of attack ranging from -4° to 28°. The lift, drag and pitching moment coefficients were compared for the cases with and without plasma control. The results revealed that the maximum control effect was achieved by placing the actuator at the leading edge of the inner and middle wing, for which the maximum lift coefficient increased by 37.8% and the stall angle of attack was postponed by 8° compared with the plasma-off case. The effects of modulation frequency and discharge voltage were also investigated. The results revealed that the lift enhancement effect of the NS-DBD plasma actuators was strongly influenced by the modulation frequency. Significant control effects were obtained at f = 70 Hz, corresponding to F + ≈ 1. The result for the pitching moment coefficient demonstrated that the plasma actuator can induce the reattachment of the separation flows when it is actuated. However, the results indicated that the discharge voltage had a negligible influence on the lift enhancement effect. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li class="active">21</li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_22" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li class="active">22</li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="421"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28205247','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28205247">A novel freeze-dried storage and preparation method for the determination of mycophenolic acid in plasma by high-performance liquid chromatography.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Wang, Lei; Qiang, Wei; Li, Ying; Cheng, Zeneng; Xie, Mengmeng 2017-09-01 Plasma samples were conventionally stored at freezing conditions until the time of detection. Such a technique, when carried out over an extended period, is energy consuming; in addition, preparation and transportation of stored samples is inconvenient. In this study, a freeze-dried storage and preparation method was proposed to determine the presence of mycophenolic acid (MPA) in plasma. Fresh plasma samples were freeze-dried using a device, and then stored at ambient temperature. After the stored samples were soaked with methanol spiked with the internal standard, high-performance liquid chromatography was conducted to detect MPA. The proposed method was demonstrated to be precise and accurate over the linear range of 0.5-50 μg mL -1 , with both intra- and inter-day precision being <7% and biases <10%. The freeze-dried samples were stable at ambient temperature for at least 40 days. This method was also successfully applied to the pharmacokinetic study of MPA in healthy volunteers. Pharmacokinetic parameters, such as maximum plasma concentration, time point of maximum plasma concentration and elimination half-life, among others, were consistent with the results in the published study. This proposed technique was proved to be simple, reproducible and energy saving. This approach could also simplify the storage and analysis of samples in clinical and scientific drug research. Copyright © 2017 John Wiley & Sons, Ltd. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25970377','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25970377">Colour Doppler Ultrasonography as a Tool to Assess Luteal Function in Santa Inês Ewes.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Figueira, L M; Fonseca, J F; Arashiro, Ekn; Souza-Fabjan, Jmg; Ribeiro, Acs; Oba, E; Viana, Jhm; Brandão, F Z 2015-08-01 The aim of this study was to evaluate luteal dynamics in the Santa Inês ewes using colour Doppler (CD) ultrasonography. Oestrus was synchronized in nulliparous females (n = 18), and subsequently, they were only teased (n = 6) or teased and mated (n = 12). Blood samples were collected daily for plasma progesterone (P4 ) concentrations. Ultrasonographic images of corpora lutea (CL) in CD mode were obtained for further analysis in its largest diameter. The CD mode allowed an early sequential monitoring of CL that was visualized by the first time 0.77 ± 0.62 days after ovulation, with luteal area 29.68 ± 13.21 mm(2) . During the luteogenesis, a progressive increase was observed, followed by a plateau of luteal area, vascularization area and plasma concentrations of P4 reaching maximum values in D11 (124.0 ± 38.0 mm(2) , 52.78 ± 24.08 mm(2) and 11.23 ± 4.89 ng/ml, respectively). In the luteolysis, the plasma concentrations of P4 decreased sharply, whereas luteal and vascularization area gradually. The vascularization area was positively correlated with plasma concentrations of P4 during the luteogenesis (r = 0.22) and luteolysis (r = 0.48). The luteal dynamics of Santa Inês ewes showed patterns similar to those observed in other sheep breeds studied. The CD ultrasonography has the potential to be used as a tool to assess luteal function in sheep. © 2015 Blackwell Verlag GmbH. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22492211-observation-periodic-runaway-reactive-ar-sub-high-power-impulse-magnetron-sputtering-discharge','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22492211-observation-periodic-runaway-reactive-ar-sub-high-power-impulse-magnetron-sputtering-discharge">Observation of a periodic runaway in the reactive Ar/O{sub 2} high power impulse magnetron sputtering discharge</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Shayestehaminzadeh, Seyedmohammad, E-mail: ses30@hi.is, E-mail: shayesteh@mch.rwth-aachen.de; Arnalds, Unnar B.; Magnusson, Rögnvaldur L. 2015-11-15 This paper reports the observation of a periodic runaway of plasma to a higher density for the reactive discharge of the target material (Ti) with moderate sputter yield. Variable emission of secondary electrons, for the alternating transition of the target from metal mode to oxide mode, is understood to be the main reason for the runaway occurring periodically. Increasing the pulsing frequency can bring the target back to a metal (or suboxide) mode, and eliminate the periodic transition of the target. Therefore, a pulsing frequency interval is defined for the reactive Ar/O{sub 2} discharge in order to sustain the plasmamore » in a runaway-free mode without exceeding the maximum power that the magnetron can tolerate.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22811077','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22811077">A scalable, micropore, platelet rich plasma separation device.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Dickson, Mary Nora; Amar, Levy; Hill, Michael; Schwartz, Joseph; Leonard, Edward F 2012-12-01 We have designed a novel, low energy platelet-rich-plasma (PRP) separator capable of producing 50 mL of PRP in 30 min, intended for military and emergency applications. Blood flows over a 3 mm length of sieve at high rates of shear. A plasma-platelet filtrate passes through the sieve's pores while erythrocytes remain. The filtrate is flowed over a second 3 mm length of smaller-pored sieve that withdraws plasma. Bulk blood volume is maintained by returning platelet-free plasma to the erythrocyte pool, enabling a nearly complete multi-pass platelet extraction. The total percentage of platelets extracted is:θ(T)=1-exp (-V(f)(T)Φ(P)/V) where V is the original plasma volume, V ( f )(T) is the total filtered volume, and ϕ ( P ) is platelet passage ratio (filtrate concentration/bulk average concentration) taken to be constant. Maximum θ(T) occurs at maximum V ( f )(T)× ϕ ( P ) Test microsieves, 3 mm long × 3 mm wide, were used. ϕ ( P ) values measured at various filtrate flow rates (20-100 uL/min) and utilizing various filter pore sizes (1.2-3.5 μm), was as high as 150 %. Maximum V ( f )(T)× ϕ ( P ) was achieved utilizing the 3.5 um filters at the highest flow rate, 100 uL/min. Erythrocyte leakages were always below 2,000/uL, far below the allowable limit stipulated by the American Association of Blood Banking. These data imply that a 13.7 cm(2) filter area is sufficient to achieve the target separation of 50 mL of platelet concentrate in 30 min. The filtration cartridge would consist of multiple microporous strips of 3 mm width arranged in parallel so that each element would see the conditions used in the prototype experiments presented here. Other microfiltration schemes suggest no method of scaling to practical levels. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009APS..DPPJO4012R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009APS..DPPJO4012R">Point-source helicity injection for ST plasma startup in Pegasus</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Redd, A. J.; Battaglia, D. J.; Bongard, M. W.; Fonck, R. J.; Schlossberg, D. J. 2009-11-01 Plasma current guns are used as point-source DC helicity injectors for forming non-solenoidal tokamak plasmas in the Pegasus Toroidal Experiment. Discharges driven by this injection scheme have achieved Ip>= 100 kA using Iinj<= 4 kA. They form at the outboard midplane, transition to a tokamak-like equilibrium, and continue to grow inward as Ip increases due to helicity injection and outer- PF induction. The maximum Ip is determined by helicity balance (injection rate vs resistive dissipation) and a Taylor relaxation limit, in which Ip√ITF Iinj/w, where w is the radial thickness of the gun-driven edge. Preliminary experiments tentatively confirm these scalings with ITF, Iinj, and w, increasing confidence in this simple relaxation model. Adding solenoidal inductive drive during helicity injection can push Ip up to, but not beyond, the predicted relaxation limit, demonstrating that this is a hard performance limit. Present experiments are focused on increasing the injection voltage (i.e., helicity injection rate) and reducing w. Near-term goals are to further test scalings predicted by the simple relaxation model and to study in detail the observed bursty n=1 activity correlated with rapid increases in Ip. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JPhD...50j5206D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JPhD...50j5206D">A comparative study of the reduction of silver and gold salts in water by a cathodic microplasma electrode</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> De Vos, Caroline; Baneton, Joffrey; Witzke, Megan; Dille, Jean; Godet, Stéphane; Gordon, Michael J.; Mohan Sankaran, R.; Reniers, François 2017-03-01 A comparative study of the reduction of aqueous silver (Ag) and gold (Au) salts to colloidal Ag and Au nanoparticles, respectively, by a gaseous, cathodic, atmospheric-pressure microplasma electrode is presented. The resulting nanoparticles (NPs) were characterized by ultraviolet-visible (UV-vis) absorption spectroscopy and transmission electron microscopy (TEM), and the aqueous solution composition before and after experiments was determined by ionic conductivity, electrochemical potential, and/or UV-vis absorption measurements. TEM showed that Ag and Au NPs were spherical and non-agglomerated when synthesized in the presence of a stabilizer, polyvinyl alcohol. The charge injected by the plasma was correlated to the maximum intensity in the absorbance spectra which in turn depends on the nanoparticle concentration. Separately, the charge injected was correlated to the metal cation concentration. Ag and Au reduction rates were found to be directly proportional to the charge injected, independent of plasma current and process time. Differences in the mechanism for Ag and Au reduction were also observed, and solution species generated by the plasma and their role in the reduction process (e.g. H2O2, electrons) is discussed. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017APS..DPPJ11099H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017APS..DPPJ11099H">Characterization and Mitigation of ICRF Antenna - Plasma Edge Interaction</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Hong, Rongjie; Tynan, George; Wukitch, Steve; Lin, Yijun; Terry, Jim; Chilenski, M.; Golfinopoulos, T.; Hubbard, A.; Mumgaard, R. T.; Perkins, R.; Reinke, M. L.; Alcator C-Mod Team 2017-10-01 Recent experiments reveal that RF-induced potentials (VRF) in the SOL and impurity source at the antenna can be reduced to background levels via optimizing the power ratio between the inner and outer current straps, Pcent /Pout . Experiments indicate the antenna impurity source reduction for the field aligned antenna is due to geometrical alignment rather than electrical symmetry. Additional experiments performed without an optimized Pcent /Pout showed that VRF and the associated convection cells do not influence the impurity penetration or core impurity confinement. These results suggest the core impurity contamination associated with ICRF heating is dominated by an increased impurity source rather than a change in impurity transport. Further, the convective cell strength was expected to scale inversely with B-field. The observed poloidal velocity (measure of convective cell strength), however, decreased less than expected. In addition, the measured maximum VRF increased and penetrated farther into the SOL at higher B-field and plasma current. Results also suggest VRF is strongly influenced by the SOL plasma parameters rather than by RF parameters. Work supported by the U.S. DoE, Office of Science, Office of Fusion Energy Sciences, User Facility Alcator C-Mod under DE-FC02-99ER54512 and DE-SC 0010720. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26641047','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26641047">Temporal plasma vitamin concentrations are altered by fat-soluble vitamin administration in suckling pigs.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Jang, Y D; Ma, J Y; Monegue, J S; Monegue, H J; Stuart, R L; Lindemann, M D 2015-11-01 Piglets are born with purportedly low plasma vitamin D levels. The objective of this study was to investigate the effect of fat-soluble vitamin administration, primarily vitamin D, by different administration routes on plasma vitamin concentrations in suckling pigs. A total of 45 pigs from 5 litters were allotted at birth to 3 treatments within each litter. Pigs were administered 400 IU of α-tocopherol, 40,000 IU of retinyl palmitate, and 40,000 IU of vitamin D at d 1 of age either orally or by i.m. injection and compared with control pigs with no supplemental vitamin administration. Blood samples were collected at d 0 (initial), 1, 2, 3, 4, 6, 9, 14, and 20 after administration. Plasma 25-hydroxycholecalciferol (25OHD), α-tocopherol, retinyl palmitate, and retinol concentrations were analyzed. Except for retinol, the effects of treatment, day, and day × treatment interaction ( < 0.01) were observed on plasma vitamin concentrations. Plasma concentrations of 25OHD and α-tocopherol increased immediately regardless of administration routes to peak at d 2 and 1 after administration, respectively. Plasma retinyl palmitate concentrations increased only with the injection treatment, with the peak at d 1 after administration. Plasma concentrations of 25OHD in both administration treatments and α-tocopherol in the injection treatment were maintained at greater levels than those in the control treatment until d 20 after administration. With regard to the pharmacokinetic parameters for plasma 25OHD concentrations, the injection treatment had greater elimination half-life ( < 0.01), maximum plasma concentrations ( < 0.05), and all area under the curve parameters ( < 0.01) but a lower elimination rate constant ( < 0.01) than the oral treatment. Relative bioavailability of oral administration compared with injection administration was 55.26%. These results indicate that plasma status of 25OHD,α-tocopherol, and retinyl palmitate are differentially changed between types of vitamins administered and between administration routes and that the injection route had a greater increase and slower disappearance of plasma vitamin levels than the oral route during the suckling period. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/7787215','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/7787215">Cholecystokinin in the control of gastric acid and plasma gastrin and somatostatin secretion in healthy subjects and duodenal ulcer patients before and after eradication of Helicobacter pylori.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Konturek, J W 1994-12-01 Exogenous cholecystokinin (CCK) is known to effect gastric secretory and motor functions but its physiological role in the control of these functions in healthy subjects and duodenal ulcer (DU) patients is unknown. In this study involving four series of young healthy normal and DU subjects, the gastric secretory tests were performed under basal conditions and following stimulation by modified sham-feeding (MSF), i.v. infusion of caerulein, gastrin releasing peptide (GRP) or pentagastrin (p-gastrin) (series A), after 500 ml of standard meal without or with addition of 15% soybean oil (series B) or acidification of meal to pH 2.5 (series C), and finally after eradication of Helicobacter pylori (HP) (series D). Studies were carried out without or with the pretreatment with placebo or loxiglumide, a specific antagonist of type A CCK receptors. In series A, the gastric secretion obtained by aspiration technique was measured after secretagogues (MSF, caerulein, GRP or p-gastrin), whereas in series B, C, and D intragastric pH was measured before and after test meal and plasma gastrin, CCK and somatostatin were assayed by specific radioimmunoassays. In healthy subjects, MSF increased gastric acid outputs to about 36% of p-gastrin maximum and treatment with loxiglumide failed to affect this secretion. Standard meal enhanced acid output to about 50% of p-gastrin maximum and raised plasma levels of gastrin, CCK but not somatostatin. The pretreatment with loxiglumide resulted in further increase both in gastric acid secretion and plasma gastrin and CCK, while somatostatin level was significantly reduced. Infusion of graded doses of caerulein or GRP resulted in dose-dependent stimulation of gastric acid secretion reaching, respectively, 35% and 25% of p-gastrin maximum. When loxiglumide was added, the acid responses to caerulein and GRP were further increased by 2-3 folds, attaining a peak similar to the p-gastrin maximum. Administration of loxiglumide resulted in a significant increase in plasma gastrin and CCK responses to GRP, whereas plasma somatostatin was not significantly altered. Addition of fat to standard meal prolonged gastric emptying of this meal by about 50% both in healthy subjects and DU patients (series B). Fat in healthy subjects significantly increased and prolonged intragastric pH after the meal while reducing the increments in plasma gastrin and enhancing plasma CCK without alteration of plasma somatostatin. Pretreatment with loxiglumide significantly reduced postprandial pH from control 4.8 to 2.5 and reversed the changes in pH caused by addition of fat. The increments in plasma gastrin and CCK were markedly augmented, whereas those of somatostatin were attenuated. DU patients showed lower postprandial pH (3.0) in tests with or without fat and higher increments in plasma gastrin. CCK antagonism failed to affect significantly the pH profile or the increments in plasma gastrin or CCK. CCK antagonism failed to affect significantly the pH profile or the increments in plasma gastrin. Intragastric application of standard meal of pH 3.0 in healthy subjects and DU patients (series C) resulted in significantly lower median 3 h intragastric pH as compared to that after meal of pH 6.5. After pretreatment with loxiglumide, the median pH after meals of both pHs was significantly lower in healthy subjects but not in DU patients. This reduction in pH was accompanied by more pronounced increase in plasma gastrin response to a meal of pH 6.5 only in healthy controls but not in DU subjects and by a significant increase in plasma CCK and decrease in plasma somatostatin. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22263914-assessment-field-aligned-icrf-antenna','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22263914-assessment-field-aligned-icrf-antenna">Assessment of a field-aligned ICRF antenna</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Wukitch, S. J.; Brunner, D.; Ennever, P. Impurity contamination and localized heat loads associated with ion cyclotron range of frequency (ICRF) antenna operation are among the most challenging issues for ICRF utilization.. Another challenge is maintaining maximum coupled power through plasma variations including edge localized modes (ELMs) and confinement transitions. Here, we report on an experimental assessment of a field aligned (FA) antenna with respect to impurity contamination, impurity sources, RF enhanced heat flux and load tolerance. In addition, we compare the modification of the scrape of layer (SOL) plasma potential of the FA antenna to a conventional, toroidally aligned (TA) antenna, in order to explore themore » underlying physics governing impurity contamination linked to ICRF heating. The FA antenna is a 4-strap ICRF antenna where the current straps and antenna enclosure sides are perpendicular to and the Faraday screen rods are parallel to the total magnetic field. In principle, alignment with respect to the total magnetic field minimizes integrated E∥ (electric field along a magnetic field line) via symmetry. Consistent with expectations, we observed that the impurity contamination and impurity source at the FA antenna are reduced compared to the TA antenna. In both L and H-mode discharges, the radiated power is 20–30% lower for a FA-antenna heated discharge than a discharge heated with the TA-antennas. Further we observe that the fraction of RF energy deposited upon the antenna is less than 0.4 % of the total injected RF energy in dipole phasing. The total deposited energy increases significantly when the FA antenna is operated in monopole phasing. The FA antenna also exhibits an unexpected load tolerance for ELMs and confinement transitions compared to the TA antennas. However, inconsistent with expectations, we observe RF induced plasma potentials to be nearly identical for FA and TA antennas when operated in dipole phasing. In monopole phasing, the FA antenna has the highest plasma potentials and poor heating efficiency despite calculations indicating low integrated E∥. In mode conversion heating scenario, no core waves were detected in the plasma core indicating poor wave penetration. For monopole phasing, simulations suggest the antenna spectrum is peaked at very short wavelength and full wave simulations show the short wavelength has poor wave penetration to the plasma core.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012epsc.conf..363Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012epsc.conf..363Y">Earth-orbiting extreme ultraviolet spectroscopic mission: SPRINT-A/EXCEED</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Yoshikawa, I.; Tsuchiya, F.; Yamazaki, A.; Yoshioka, K.; Uemizu, K.; Murakami, G.; Kimura, T.; Kagitani, M.; Terada, N.; Kasaba, Y.; Sakanoi, T.; Ishii, H.; Uji, K. 2012-09-01 The EXCEED (Extreme Ultraviolet Spectroscope for Exospheric Dynamics) mission is an Earth-orbiting extreme ultraviolet (EUV) spectroscopic mission and the first in the SPRINT series being developed by ISAS/JAXA. It will be launched in the summer of 2013. EUV spectroscopy is suitable for observing tenuous gases and plasmas around planets in the solar system (e.g., Mercury, Venus, Mars, Jupiter, and Saturn). Advantage of remote sensing observation is to take a direct picture of the plasma dynamics and distinguish between spatial and temporal variability explicitly. One of the primary observation targets is an inner magnetosphere of Jupiter, whose plasma dynamics is dominated by planetary rotation. Previous observations have shown a few percents of the hot electron population in the inner magnetosphere whose temperature is 100 times higher than the background thermal electrons. Though the hot electrons have a significant impact on the energy balance in the inner magnetosphere, their generation process has not yet been elucidated. In the EUV range, a number of emission lines originate from plasmas distributed in Jupiter's inner magnetosphere. The EXCEED spectrograph is designed to have a wavelength range of 55-145 nm with minimum spectral resolution of 0.4 nm, enabling the electron temperature and ion composition in the inner magnetosphere to be determined. Another primary objective is to investigate an unresolved problem concerning the escape of the atmosphere to space. Although there have been some in-situ observations by orbiters, our knowledge is still limited. The EXCEED mission plans to make imaging observations of plasmas around Venus and Mars to determine the amounts of escaping atmosphere. The instrument's field of view (FOV) is so wide that we can get an image from the interaction region between the solar wind and planetary plasmas down to the tail region at one time. This will provide us with information about outward-flowing plasmas, e.g., their composition, rate, and dependence on solar activity. EXCEED has two mission instruments: the EUV spectrograph and a target guide camera that is sensitive to visible light. The EUV spectrograph is designed to have a wavelength range of 55-145 nm with a spectral resolution of 0.4-1.0 nm. The spectrograph slits have a FOV of 400 x 140 arcseconds (maximum). The optics of the instrument consists of a primary mirror with a diameter of 20cm, a laminar type grating, and a 5-stage micro-channel plate assembly with a resistive anode encoder. To achieve high efficiencies, the surfaces of the primary mirror and the grating are coated with CVD-SiC. Because of the large primary mirror and high efficiencies, good temporal resolution and complete spatial coverage for Io plasma torus observation is expected. Based on a feasibility study using the spectral diagnosis method, it is shown that EXCEED can determine the Io plasma torus parameters, such as the electron density, temperatures, hot electron fraction and so on, using an exposure time of 50 minutes. The target guide camera will be used to capture the target and guide the observation area of interest to the slit. Emissions from outside the slit's FOV will be reflected by the front of the slit and guided to the target guide camera. The guide camera's FOV is 240" x 240". The camera will take an image every 3 seconds and the image is sent to a mission data processor (MDP), which calculates the centroid of the image. During an observation, the bus system controls the attitude to keep the centroid position of the target in the guide camera with an accuracy of ±5 arc-seconds. With the help of the target guide camera, we will take spectral images with a long exposure time of 50 minutes and good spatial resolution of 20 arc-seconds. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFMSM23B2611N','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFMSM23B2611N">Arecibo - HF experiments in the E_region</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Nossa, E.; Jain, K.; Sulzer, M. P.; Perillat, P. 2017-12-01 The new Arecibo Observatory - HF facility started operations in 2015. The HF facility is fully operational, acquiring consecutive days of data without unwanted interruptions. It has a maximum transmitted power of 600kW, with center frequencies at 5.125 MHz and 8.175 MHz. The 8.175 (5.125) MHz band frequency has a gain of 25.5 (22) dB and HPBW of 8.5 (13) degrees. The effects of the HF experiments in the ionosphere are being observed with the Arecibo incoherent scatter radar (ISR). The ISR has two beams that simultaneously could sense the modified region and the region outside of the affected volume. The ISR has height resolution of 300 m. and allows to observe from altitudes 95 km to the topside ionosphere. Observation of the E-region - HF experiments are sparse but possible at Arecibo. High ionization at a height 100 km are needed to modify the region artificially. This paper presents examples of E-region enhanced plasma lines (See Figure). Diagnostic of the layers is made using the ISR to estimate electron density, temperatures, ion drifts, among others. The data shows exceptional modifications of the ionosphere that range from creating artificial cavities and layers, induced irregularities, substantial variations in temperature profiles to enhanced ion and plasma densities.Previously, the HF experiments were performed to study specific effects in a narrow region. However, the extent of the data collected with the ISR during 2017 is revealing new features and different kind of forces that artificially modify extended regions of the ionosphere. This paper exhibits examples where the interaction between the E and F-region when HF experiments are evident. A theory of a correlation between the two layers due to different conductivities is explored to illustrate how the enhancement of irregularities is produced and maintained over time. Examples of strong artificially induced irregularities formed at F-region heights when Sporadic E-layer is present are shown to support the theory.The Figure shows an enhanced plasma line for the diurnal E-region. For this HF experiment, the plasma density increased from 3.6 MHz to 5.1MHz (which corresponds to the HF frequency). The vertical lines observed in the Figure are artifacts from the data, as well as the fake enhanced plasma lines at frequencies different than the HF frequency. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19910009603','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19910009603">Simultaneous Solar Maximum Mission (SMM) and Very Large Array (VLA) observations of solar active regions</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Willson, Robert F. 1991-01-01 Very Large Array observations at 20 cm wavelength can detect the hot coronal plasma previously observed at soft x ray wavelengths. Thermal cyclotron line emission was detected at the apex of coronal loops where the magnetic field strength is relatively constant. Detailed comparison of simultaneous Solar Maximum Mission (SMM) Satellite and VLA data indicate that physical parameters such as electron temperature, electron density, and magnetic field strength can be obtained, but that some coronal loops remain invisible in either spectral domain. The unprecedent spatial resolution of the VLA at 20 cm wavelength showed that the precursor, impulsive, and post-flare components of solar bursts originate in nearby, but separate loops or systems of loops.. In some cases preburst heating and magnetic changes are observed from loops tens of minutes prior to the impulsive phase. Comparisons with soft x ray images and spectra and with hard x ray data specify the magnetic field strength and emission mechanism of flaring coronal loops. At the longer 91 cm wavelength, the VLA detected extensive emission interpreted as a hot 10(exp 5) K interface between cool, dense H alpha filaments and the surrounding hotter, rarefield corona. Observations at 91 cm also provide evidence for time-correlated bursts in active regions on opposite sides of the solar equator; they are attributed to flare triggering by relativistic particles that move along large-scale, otherwise-invisible, magnetic conduits that link active regions in opposite hemispheres of the Sun. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JaJAP..57fJH02S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JaJAP..57fJH02S">Silicon etching of difluoromethane atmospheric pressure plasma jet combined with its spectroscopic analysis</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Sung, Yu-Ching; Wei, Ta-Chin; Liu, You-Chia; Huang, Chun 2018-06-01 A capacitivly coupled radio-frequency double-pipe atmospheric-pressure plasma jet is used for etching. An argon carrier gas is supplied to the plasma discharge jet; and CH2F2 etch gas is inserted into the plasma discharge jet, near the silicon substrate. Silicon etchings rate can be efficiently-controlled by adjusting the feeding etching gas composition and plasma jet operating parameters. The features of silicon etched by the plasma discharge jet are discussed in order to spatially spreading plasma species. Electronic excitation temperature and electron density are detected by increasing plasma power. The etched silicon profile exhibited an anisotropic shape and the etching rate was maximum at the total gas flow rate of 4500 sccm and CH2F2 concentration of 11.1%. An etching rate of 17 µm/min was obtained at a plasma power of 100 W. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23355638','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23355638">A physiologically based pharmacokinetic model to predict disposition of CYP2D6 and CYP1A2 metabolized drugs in pregnant women.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Ke, Alice Ban; Nallani, Srikanth C; Zhao, Ping; Rostami-Hodjegan, Amin; Isoherranen, Nina; Unadkat, Jashvant D 2013-04-01 Conducting pharmacokinetic (PK) studies in pregnant women is challenging. Therefore, we asked if a physiologically based pharmacokinetic (PBPK) model could be used to evaluate different dosing regimens for pregnant women. We refined and verified our previously published pregnancy PBPK model by incorporating cytochrome P450 CYP1A2 suppression (based on caffeine PK) and CYP2D6 induction (based on metoprolol PK) into the model. This model accounts for gestational age-dependent changes in maternal physiology and hepatic CYP3A activity. For verification, the disposition of CYP1A2-metabolized drug theophylline (THEO) and CYP2D6-metabolized drugs paroxetine (PAR), dextromethorphan (DEX), and clonidine (CLO) during pregnancy was predicted. Our PBPK model successfully predicted THEO disposition during the third trimester (T3). Predicted mean postpartum to third trimester (PP:T3) ratios of THEO area under the curve (AUC), maximum plasma concentration, and minimum plasma concentration were 0.76, 0.95, and 0.66 versus observed values 0.75, 0.89, and 0.72, respectively. The predicted mean PAR steady-state plasma concentration (Css) ratio (PP:T3) was 7.1 versus the observed value 3.7. Predicted mean DEX urinary ratio (UR) (PP:T3) was 2.9 versus the observed value 1.9. Predicted mean CLO AUC ratio (PP:T3) was 2.2 versus the observed value 1.7. Sensitivity analysis suggested that a 100% induction of CYP2D6 during T3 was required to recover the observed PP:T3 ratios of PAR Css, DEX UR, and CLO AUC. Based on these data, it is prudent to conclude that the magnitude of hepatic CYP2D6 induction during T3 ranges from 100 to 200%. Our PBPK model can predict the disposition of CYP1A2, 2D6, and 3A drugs during pregnancy. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3608458','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3608458">A Physiologically Based Pharmacokinetic Model to Predict Disposition of CYP2D6 and CYP1A2 Metabolized Drugs in Pregnant Women</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Ke, Alice Ban; Nallani, Srikanth C.; Zhao, Ping; Rostami-Hodjegan, Amin; Isoherranen, Nina 2013-01-01 Conducting pharmacokinetic (PK) studies in pregnant women is challenging. Therefore, we asked if a physiologically based pharmacokinetic (PBPK) model could be used to evaluate different dosing regimens for pregnant women. We refined and verified our previously published pregnancy PBPK model by incorporating cytochrome P450 CYP1A2 suppression (based on caffeine PK) and CYP2D6 induction (based on metoprolol PK) into the model. This model accounts for gestational age–dependent changes in maternal physiology and hepatic CYP3A activity. For verification, the disposition of CYP1A2–metabolized drug theophylline (THEO) and CYP2D6–metabolized drugs paroxetine (PAR), dextromethorphan (DEX), and clonidine (CLO) during pregnancy was predicted. Our PBPK model successfully predicted THEO disposition during the third trimester (T3). Predicted mean postpartum to third trimester (PP:T3) ratios of THEO area under the curve (AUC), maximum plasma concentration, and minimum plasma concentration were 0.76, 0.95, and 0.66 versus observed values 0.75, 0.89, and 0.72, respectively. The predicted mean PAR steady-state plasma concentration (Css) ratio (PP:T3) was 7.1 versus the observed value 3.7. Predicted mean DEX urinary ratio (UR) (PP:T3) was 2.9 versus the observed value 1.9. Predicted mean CLO AUC ratio (PP:T3) was 2.2 versus the observed value 1.7. Sensitivity analysis suggested that a 100% induction of CYP2D6 during T3 was required to recover the observed PP:T3 ratios of PAR Css, DEX UR, and CLO AUC. Based on these data, it is prudent to conclude that the magnitude of hepatic CYP2D6 induction during T3 ranges from 100 to 200%. Our PBPK model can predict the disposition of CYP1A2, 2D6, and 3A drugs during pregnancy. PMID:23355638 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26967321','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26967321">Impact of Cytochrome P450 2D6 Function on the Chiral Blood Plasma Pharmacokinetics of 3,4-Methylenedioxymethamphetamine (MDMA) and Its Phase I and II Metabolites in Humans.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Steuer, Andrea E; Schmidhauser, Corina; Tingelhoff, Eva H; Schmid, Yasmin; Rickli, Anna; Kraemer, Thomas; Liechti, Matthias E 2016-01-01 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) metabolism is known to be stereoselective, with preference for S-stereoisomers. Its major metabolic step involves CYP2D6-catalyzed demethylenation to 3,4-dihydroxymethamphetamine (DHMA), followed by methylation and conjugation. Alterations in CYP2D6 genotype and/or phenotype have been associated with higher toxicity. Therefore, the impact of CYP2D6 function on the plasma pharmacokinetics of MDMA and its phase I and II metabolites was tested by comparing extensive metabolizers (EMs), intermediate metabolizers (IMs), and EMs that were pretreated with bupropion as a metabolic inhibitor in a controlled MDMA administration study. Blood plasma samples were collected from 16 healthy participants (13 EMs and three IMs) up to 24 h after MDMA administration in a double-blind, placebo-controlled, four-period, cross-over design, with subjects receiving 1 week placebo or bupropion pretreatment followed by a single placebo or MDMA (125 mg) dose. Bupropion pretreatment increased the maximum plasma concentration (Cmax) and area under the plasma concentration-time curve from 0 to 24 h (AUC24) of R-MDMA (9% and 25%, respectively) and S-MDMA (16% and 38%, respectively). Bupropion reduced the Cmax and AUC24 of the CYP2D6-dependently formed metabolite stereoisomers of DHMA 3-sulfate, DHMA 4-sulfate, and 4-hydroxy-3-methoxymethamphetamine (HMMA sulfate and HMMA glucuronide) by approximately 40%. The changes that were observed in IMs were generally comparable to bupropion-pretreated EMs. Although changes in stereoselectivity based on CYP2D6 activity were observed, these likely have low clinical relevance. Bupropion and hydroxybupropion stereoisomer pharmacokinetics were unaltered by MDMA co-administration. The present data might aid further interpretations of toxicity based on CYP2D6-dependent MDMA metabolism. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4788153','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4788153">Impact of Cytochrome P450 2D6 Function on the Chiral Blood Plasma Pharmacokinetics of 3,4-Methylenedioxymethamphetamine (MDMA) and Its Phase I and II Metabolites in Humans</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Steuer, Andrea E.; Schmidhauser, Corina; Tingelhoff, Eva H.; Schmid, Yasmin; Rickli, Anna; Kraemer, Thomas; Liechti, Matthias E. 2016-01-01 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) metabolism is known to be stereoselective, with preference for S-stereoisomers. Its major metabolic step involves CYP2D6-catalyzed demethylenation to 3,4-dihydroxymethamphetamine (DHMA), followed by methylation and conjugation. Alterations in CYP2D6 genotype and/or phenotype have been associated with higher toxicity. Therefore, the impact of CYP2D6 function on the plasma pharmacokinetics of MDMA and its phase I and II metabolites was tested by comparing extensive metabolizers (EMs), intermediate metabolizers (IMs), and EMs that were pretreated with bupropion as a metabolic inhibitor in a controlled MDMA administration study. Blood plasma samples were collected from 16 healthy participants (13 EMs and three IMs) up to 24 h after MDMA administration in a double-blind, placebo-controlled, four-period, cross-over design, with subjects receiving 1 week placebo or bupropion pretreatment followed by a single placebo or MDMA (125 mg) dose. Bupropion pretreatment increased the maximum plasma concentration (Cmax) and area under the plasma concentration-time curve from 0 to 24 h (AUC24) of R-MDMA (9% and 25%, respectively) and S-MDMA (16% and 38%, respectively). Bupropion reduced the Cmax and AUC24 of the CYP2D6-dependently formed metabolite stereoisomers of DHMA 3-sulfate, DHMA 4-sulfate, and 4-hydroxy-3-methoxymethamphetamine (HMMA sulfate and HMMA glucuronide) by approximately 40%. The changes that were observed in IMs were generally comparable to bupropion-pretreated EMs. Although changes in stereoselectivity based on CYP2D6 activity were observed, these likely have low clinical relevance. Bupropion and hydroxybupropion stereoisomer pharmacokinetics were unaltered by MDMA co-administration. The present data might aid further interpretations of toxicity based on CYP2D6-dependent MDMA metabolism. PMID:26967321 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017PPCF...59d4001L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017PPCF...59d4001L">Effect of rotation zero-crossing on single-fluid plasma response to three-dimensional magnetic perturbations</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Lyons, B. C.; Ferraro, N. M.; Paz-Soldan, C.; Nazikian, R.; Wingen, A. 2017-04-01 In order to understand the effect of rotation on the response of a plasma to three-dimensional magnetic perturbations, we perform a systematic scan of the zero-crossing of the rotation profile in a DIII-D ITER-similar shape equilibrium using linear, time-independent modeling with the M3D-C1 extended magnetohydrodynamics code. We confirm that the local resonant magnetic field generally increases as the rotation decreases at a rational surface. Multiple peaks in the resonant field are observed near rational surfaces, however, and the maximum resonant field does not always correspond to zero rotation at the surface. Furthermore, we show that non-resonant current can be driven at zero-crossings not aligned with rational surfaces if there is sufficient shear in the rotation profile there, leading to amplification of near-resonant Fourier harmonics of the perturbed magnetic field and a decrease in the far-off-resonant harmonics. The quasilinear electromagnetic torque induced by this non-resonant plasma response provides drive to flatten the rotation, possibly allowing for increased transport in the pedestal by the destabilization of turbulent modes. In addition, this torque acts to drive the rotation zero-crossing to dynamically stable points near rational surfaces, which would allow for increased resonant penetration. By one or both of these mechanisms, this torque may play an important role in bifurcations into suppression of edge-localized modes. Finally, we discuss how these changes to the plasma response could be detected by tokamak diagnostics. In particular, we show that the changes to the resonant field discussed here have a significant impact on the external perturbed magnetic field, which should be observable by magnetic sensors on the high-field side of tokamaks but not on the low-field side. In addition, TRIP3D-MAFOT simulations show that none of the changes to the plasma response described here substantially affects the divertor footprint structure. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1374819-effect-rotation-zero-crossing-single-fluid-plasma-response-three-dimensional-magnetic-perturbations','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1374819-effect-rotation-zero-crossing-single-fluid-plasma-response-three-dimensional-magnetic-perturbations">Effect of rotation zero-crossing on single-fluid plasma response to three-dimensional magnetic perturbations</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a> Lyons, Brendan C.; Ferraro, Nathaniel M.; Paz-Soldan, Carlos A.; ... 2017-02-14 In order to understand the effect of rotation on the plasma's response to three-dimensional magnetic perturbations, we perform a systematic scan of the zero-crossing of the rotation profile in a DIII-D ITER-similar shape equilibrium using linear, time-independent modeling with the M3D-C1 extended magnetohydrodynamics code. We confirm that the local resonant magnetic field generally increases as the rotation decreases at a rational surface. Multiple peaks in the resonant field are observed near rational surfaces, however, and the maximum resonant field does not always correspond to zero rotation at the surface. Furthermore, we show that non-resonant current can be driven at zero-more » crossings not aligned with rational surfaces if there is sufficient shear in the rotation profile there, leading to an amplification of near-resonant Fourier harmonics of the perturbed magnetic field and a decrease in the far-off -resonant harmonics. The quasilinear electromagnetic torque induced by this non-resonant plasma response provides drive to flatten the rotation, possibly allowing for increased transport in the pedestal by the destabilization of turbulent modes. In addition, this torque acts to drive the rotation zero-crossing to dynamically stable points near rational surfaces, which would allow for increased resonant penetration. By one or both of these mechanisms, this torque may play an important role in bifurcations into ELM suppression. Finally, we discuss how these changes to the plasma response could be detected by tokamak diagnostics. In particular, we show that the changes to the resonant field discussed here have a significant impact on the external perturbed magnetic field, which should be observable by magnetic sensors on the high-field side of tokamaks, but not on the low-field side. In addition, TRIP3D-MAFOT simulations show that none of the changes to the plasma response described here substantially affects the divertor footprint structure.« less </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li class="active">22</li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_23" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active">23</li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="441"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013ApJ...777..135B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013ApJ...777..135B">Rapid Evolution of the Solar Atmosphere during the Impulsive Phase of a Microflare Observed with the Extreme-ultraviolet Imaging Spectrometer aboard Hinode: Hints of Chromospheric Magnetic Reconnection</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Brosius, Jeffrey W. 2013-11-01 We obtained rapid cadence (11.2 s) EUV stare spectra of a solar microflare with the Extreme-ultraviolet Imaging Spectrometer aboard Hinode. The intensities of lines formed at temperatures too cool to be found in the corona brightened by factors around 16 early during this event, indicating that we observed a site of energy deposition in the chromosphere. We derive the density evolution of the flare plasma at temperature around 2 MK from the intensity ratio of Fe XIV lines at 264.789 Å and 274.204 Å. From both lines we removed the bright pre-flare quiescent emission, and from 274.204 we removed the blended emission of Si VII λ274.180 based on the Si VII λ274.180/275.361 intensity ratio, which varies only slightly with density. In this way the flare electron density is derived with emission from only the flare plasma. The density increased by an order of magnitude from its pre-flare quiescent average of (3.43 ± 0.19) × 109 cm-3 to its maximum impulsive phase value of (3.04 ± 0.57) × 1010 cm-3 in 2 minutes. The fact that this rapid increase in density is not accompanied by systematic, large upward velocities indicates that the density increase is not due to the filling of loops with evaporated chromospheric material, but rather due to material being directly heated in the chromosphere, likely by magnetic reconnection. The density increase may be due to a progression of reconnection sites to greater depths in the chromosphere, where it has access to larger densities, or it may be due to compression of 2 MK plasma by the 10 MK plasma as it attempts to expand against the high-density chromospheric plasma. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28347318','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28347318">Pharmacokinetics of surotomycin from phase 1 single and multiple ascending dose studies in healthy volunteers.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Chandorkar, Gurudatt; Zhan, Qiao; Donovan, Julie; Rege, Shruta; Patino, Hernando 2017-03-28 Surotomycin, a novel, orally administered, cyclic, lipopeptide antibacterial in development for the treatment of Clostridium difficile-associated diarrhea, has demonstrated minimal intestinal absorption in animal models. Safety, tolerability, and plasma pharmacokinetics of single and multiple ascending oral doses (SAD/MAD) of surotomycin in healthy volunteers were characterized in two randomized, double-blind, placebo-controlled, phase 1 studies. Participants were sequentially enrolled into one of four SAD (500, 1000, 2000, 4000 mg surotomycin) or three MAD (250, 500, 1000 mg surotomycin twice/day for 14 days) cohorts. Ten subjects were randomized 4:1 into each cohort to receive surotomycin or placebo. Surotomycin plasma concentrations rose as dose increased (maximum plasma concentration [C max ]: 10.5, 21.5, 66.6, and 86.7 ng/mL). Systemic levels were generally low, with peak median surotomycin plasma concentrations observed 6-12 h after the first dose. In the MAD study, surotomycin plasma concentrations were higher on day 14 (C max : 25.5, 37.6, and 93.5 ng/mL) than on day 1 (C max : 6.8, 11.0, and 21.1 ng/mL for increasing doses), indicating accumulation. In the SAD study, <0.01% of the administered dose was recovered in urine. Mean surotomycin stool concentration from the 1000 mg MAD cohort was 6394 μg/g on day 5. Both cohorts were well tolerated with all adverse events reported as mild to moderate. Both SAD and MAD studies of surotomycin demonstrated minimal systemic exposure, with feces the primary route of elimination following oral administration; consistent with observations with similar compounds, such as fidaxomicin. Results of these phase 1 studies support the continued clinical development of surotomycin for the treatment of Clostridium difficile-associated diarrhea. NCT02835118 and NCT02835105 . Retrospectively registered, July 13 2016. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018PPCF...60g5009S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018PPCF...60g5009S">Study of runaway electrons in TUMAN-3M tokamak plasmas</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Shevelev, A.; Khilkevitch, E.; Tukachinsky, A.; Pandya, S.; Askinazi, L.; Belokurov, A.; Chugunov, I.; Doinikov, D.; Gin, D.; Iliasova, M.; Kiptily, V.; Kornev, V.; Lebedev, S.; Naidenov, V.; Plyusnin, V.; Polunovsky, I.; Zhubr, N. 2018-07-01 Studies of runaway electrons in present day tokamaks are essential to improve theoretical models and to support possible avoidance or suppression mechanisms in future large-scale plasma devices. Some of the phenomena associated with the runaway electrons take place at faster time scales, and thus it is essential to probe the runaway electrons to investigate underlying physics. The present article reports a few experimental observations of runaway electron associated events, at fast time scales, using a state-of-the-art multi-detector system developed at the Ioffe Institute and recently deployed on the TUMAN-3M tokamak. The system is based on the high-performance scintillation gamma-ray spectrometers for measurements of bremsstrahlung generated during the interaction of accelerated electrons with plasma and materials of the tokamak chamber. It includes a total three detectors configured in the spectroscopic mode having different lines of sight. Along with this hardware, dedicated algorithms were developed and validated that enables the separation of piled-up pulses, maximize the dynamic range of the detector and provides a counting rate as high as 107 counts per second. The inversion code, DeGaSum, has been used for the reconstruction of a runaway electron energy distribution function from the measured gamma-ray spectra. Using this tool, experimental analysis of the runaway electron beam generation and evolution of their energy distribution in the TUMAN-3M representative plasma discharges is performed. The effect on gamma-ray count rate during the magnetohydrodynamic activities and possible changes in the runaway electron energy distribution function during sawtooth oscillations is discussed in detail. Possible maximum limit of the runaway electron energy in TUMAN-3M is investigated and compared with the numerical analysis. In addition, the probability of the runaway electron generation throughout the plasma discharge is estimated analytically and compared with the experimental observation that suggests a balance between production and loss of the runaway electrons. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010EGUGA..12.3079S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010EGUGA..12.3079S">The climatology of low latitude ionospheric currents derived from CHAMP observations</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Stolle, Claudia; Alken, Patrik 2010-05-01 The multi-year data base of magnetic field and ionospheric measurements from the CHAMP satellite contain enormous potential to investigate the behaviour and the origin of currents in the E and F region ionosphere. Special advantage is drawn from the satellite's near polar orbit and the full data coverage over all longitudes and local times. This paper will present findings about two prominent features of the low latitude ionosphere: equatorial plasma irregularities and the equatorial electrojet (EEJ). Equatorial plasma irregularities (commonly known as "bubbles") severely disturb the post sunset F region ionosphere and cause the strongest radio wave scintillations globally during solar maximum years. Using CHAMP vector magnetic field data, it was possible for the first time to show on a long term basis that equatorial plasma irregularities have signatures in all components of the magnetic field. The first ever global climatology of the occurrence rate of these magnetic signatures has been compiled. Such a data base of disturbed orbits is especially useful for core and crustal magnetic field modellers. The magnetic field observations of CHAMP, Ørsted, and SAC-C were employed to develop a climatological model of the EEJ. Measurements of the EEJ and empirical values from electron density and thermospheric density and winds have in addition enabled the development of a climatological model of the equatorial electric field. These results provide excellent opportunity to investigate the seasonal/longitudinal characteristics of the EEJ and the influence of atmospheric waves on E region dynamics. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017hst..prop15147S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017hst..prop15147S">Extreme Doppler Shifting of Io's Neutral Jets</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Schmidt, Carl 2017-08-01 The dynamics and the extension of Jupiter's magnetosphere are determined by the massive internal plasma sources combined with the fast rotation. The vast majority of the plasma originates from the atmosphere of the moon Io, the most volcanically active body in our solar system. Here we propose to characterize the density and velocity of energetic neutral atoms escaping from Io's atmosphere. Exploiting the high resolution and sensitivity of the COS G130M spectral mode, we will measure the Doppler velocities of atomic O, S and Cl streams, which are energized through charge exchange and dissociative recombination of molecular ions. Prior COS observations of Io revealed a large number of emission lines from several ion and neutral species with excellent S/N, obtained over a single HST orbit. Those spectra were obtained surrounding eclipse geometry, where Doppler shifts are minimized and were restricted to Io itself rather than the stream region. Here we will target the extended clouds with only two orbits total when the moon is at eastern and western elongation for maximum Doppler shifts. The observations will provide new constraints on the diffuse large-scale cloud structures in the Jovian system and significantly improve our understanding of the transport of mass and energy within the Io-torus interaction. The absolute brightness, in combination with plasma parameters from line ratios/collision strengths, will allow us to quantify the outflow of energetic neutral atoms from Io's main sulfur-oxygen atmosphere for the first time. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/2520523','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/2520523">Pharmacokinetics of doxylamine given as Bendectin in the pregnant monkey and baboon.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Rowland, J M; Slikker, W; Holder, C L; Denton, R; Prahalada, S; Young, J F; Hendrickx, A G 1989-01-01 The object of the present study was to determine the maternal plasma pharmacokinetics of doxylamine (the antihistamine component of Bendectin) following Bendectin administration. Bendectin was administered daily, po, at a dosage approximately 10 times the maximum human therapeutic dosage (7 mg/kg/day) throughout organogenesis (approximately days 22 through 50 of gestation) to three cynomolgus monkeys, four rhesus monkeys, and five baboons. Two pharmacokinetic experiments were performed in each animal, one on the first day of treatment and one on the last day of treatment. Although this study was not designed specifically as a teratologic examination, no morphologic abnormalities were observed when the fetuses were examined on approximately day 100 of gestation. A single-compartment, parallel first- and second-order elimination model was used to analyze the data. Although considerable interindividual variation was evident, no significant differences between species were observed when the half-life for the absorption of doxylamine from the gut or the elimination of doxylamine and metabolites from the plasma were compared. The plasma elimination half-lives and the clearance values were not altered by the 29 days of Bendectin treatment for any of the species. Only the half-life for the absorption of doxylamine in the baboon was reduced by daily dosing with Bendectin, but this did not alter doxylamine elimination. Thus, the pharmacokinetics of doxylamine administered as Bendectin were similar in the three nonhuman primate species examined and were not altered by repeated daily administration. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1981Sci...214..456G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1981Sci...214..456G">Blood-Brain Glucose Transfer: Repression in Chronic Hyperglycemia</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Gjedde, Albert; Crone, Christian 1981-10-01 Diabetic patients with increased plasma glucose concentrations may develop cerebral symptoms of hypoglycemia when their plasma glucose is rapidly lowered to normal concentrations. The symptoms may indicate insufficient transport of glucose from blood to brain. In rats with chronic hyperglycemia the maximum glucose transport capacity of the blood-brain barrier decreased from 400 to 290 micromoles per 100 grams per minute. When plasma glucose was lowered to normal values, the glucose transport rate into brain was 20 percent below normal. This suggests that repressive changes of the glucose transport mechanism occur in brain endothelial cells in response to increased plasma glucose. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA084967','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA084967">Study of the Anatomy of the X-Ray and Neutron Production Scaling Laws in the Plasma Focus (Particle Energy Spectrum and Optimization Criteria).</a> <a target="_blank" rel="noopener noreferrer" href="http://www.dtic.mil/">DTIC Science & Technology</a> 1979-11-01 plasma focus operations have been experimentally analyzed in terms of (A) The fine structure of the axial-current channel during maximum of compression. (B) Correlation coefficient, for neutron yield n (by D2 discharges) and the multiplicity of the electron beam pulses; (C) Different values of the electrode voltage. The current distribution near the axial plasma column during the explosive decay of the column has been monitored and correlated with the electron beam production. Plasma focus discharges by our mode of operation generate high-intensity </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1991QuEle..21.1359G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1991QuEle..21.1359G">EFFECTS OF LASER RADIATION ON MATTER: Influence of the ambient air pressure on short-wavelength radiation from a laser plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Golovin, A. F.; Zemtsov, S. S.; Fedyushin, B. T. 1991-12-01 A detailed experimental investigation was made of the radiation from a plasma created on an aluminum target by a pulsed CO2 laser at different ambient gas pressures. Measurements were made of the energy and angular distribution of the radiation and of the efficiency of conversion of laser energy into reemitted plasma radiation. The intensity of this radiation was found to exhibit pressure-dependent pulsations. The maximum reflection of the laser radiation from the plasma was recorded at a pressure of ~ 40 Torr. An interpretation is given of the experimental data. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2004APS..DPPFM1007R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2004APS..DPPFM1007R">Using astrophysical jets for establishing an upper limit for the photon mass</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Ryutov, D. D. 2004-11-01 Finite photon mass is compatible with general principles of the relativity theory; how small it (the mass) actually is has to be established experimentally. The presently accepted upper limit [1], E-22 of the electron mass, is established [2] based on the observations of the Solar wind. This estimate corresponds to the photon Compton length of L=3E6 km. I discuss possible ways of improving this estimate based on the properties of those of astrophysical jets where the pinch force is important for establishing the jet structure. It turns out that, if the jet radius is much greater than L, both pinch equilibrium and stability become very different from the massless photon case. In particular, the equilibrium pressure maximum coincides with the maximum of the current density. These new features are often incompatible with the observations, providing a way for improving the estimate of the photon mass by orders of magnitude. Work performed for the U.S. DOE by UC LLNL under contract W-7405-Eng-48. [1] S. Eidelman, and Particle Phys. Group. "Review of Particle Physics," Phys. Lett. B592, p.1, 2004; [2] D.D. Ryutov. Plasma Phys. Contr. Fus., 39, p.A73, 1997. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25556816','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25556816">Two main metabolites of gentiopicroside detected in rat plasma by LC-TOF-MS following 2,4-dinitrophenylhydrazine derivatization.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Wang, Zhigang; Tang, Shuhan; Jin, Yan; Zhang, Yan; Hattori, Masao; Zhang, Hailong; Zhang, Ning 2015-03-25 The metabolism of gentiopicroside in vivo was studied by LC/MS following 2,4-dinitrophenylhydrazine derivatization for the first time. The ionization efficiency of the major metabolites erythrocentaurin and gentiopicral were greatly enhanced by the new analytical method developed, and they were successfully detected in rat plasma after oral administration of gentiopicroside. Methyl 4-formylbenzoate was used as the internal standard to quantify erythrocentaurin and gentiopicral in rat plasma in negative mode by UPLC-TOF-MS. It was found that erythrocentaurin reached the maximum plasma concentration of 625.2±246.3 ng/mL at about 2 h and gentiopicral reached the maximum plasma concentration of 157.6±86.6 ng/mL at about 4 h after oral administration of gentiopicroside at a dose of 200 mg/kg. The metabolic pathway of gentiopicroside to erythrocentaurin and gentiopicral was proposed. The monoterpene compound gentiopicroside was found to be metabolized to dihydroisocoumarin in vivo which may be responsible for the pharmacological effect of gentiopicroside. The results may shed light on clinical efficacy of gentiopicroside and the new analytical method developed may assist in studies for the metabolism of other natural iridoids and secoiridoids in vivo. Copyright © 2015 Elsevier B.V. All rights reserved. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19950029547&hterms=THEORY+LAYER+LIMIT&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3DTHEORY%2BLAYER%2BLIMIT','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19950029547&hterms=THEORY+LAYER+LIMIT&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3DTHEORY%2BLAYER%2BLIMIT">Magnetic spectral signatures in the Earth's magnetosheath and plasma depletion layer</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Anderson, Brian J.; Fuselier, Stephen A.; Gary, S. Peter; Denton, Richard E. 1994-01-01 Correlations between plasma properties and magnetic fluctuations in the sub-solar magnetosheath downstream of a quasi-perpendicular shock have been found and indicate that mirror and ion cyclotronlike fluctuations correlate with the magnetosheath proper and plasma depletion layer, respectively (Anderson and Fueselier, 1993). We explore the entire range of magnetic spectral signatures observed from the Active Magnetospheric Particle Tracer Explorers/Charge Composition Explorer (AMPTE/CCE)spacecraft in the magnetosheath downstream of a quasi-perpendicular shock. The magnetic spectral signatures typically progress from predominantly compressional fluctuations,delta B(sub parallel)/delta B perpendicular to approximately 3, with F/F (sub p) less than 0.2 (F and F (sub p) are the wave frequency and proton gyrofrequency, respectively) to predominantly transverse fluctuations, delta B(sub parallel)/delta B perpendicular to approximately 0.3, extending up to F(sub p). The compressional fluctuations are characterized by anticorrelation between the field magnitude and electron density, n(sub e), and by a small compressibility, C(sub e) identically equal to (delta n(sub e)/n(sub e)) (exp 2) (B/delta B(sub parallel)) (exp 2) approximately 0.13, indicative of mirror waves. The spectral characteristics of the transverse fluctuations are in agreement with predictions of linear Vlasov theory for the H(+) and He(2+) cyclotron modes. The power spectra and local plasma parameters are found to vary in concert: mirror waves occur for beta(s ub parallel p) (beta (sub parallel p) identically = 2 mu(sub zero) n(sub p) kT (sub parallel p) / B(exp 2) approximately = 2, A(sub p) indentically = T(sub perpendicular to p)/T(sub parallel p) - 1 approximately = 0.4, whereas cyclotron waves occur for beta (sub parallel p) approximately = 0.2 and A(sub p) approximately = 2. The transition from mirror to cyclotron modes is predicted by linear theory. The spectral characteristics overlap for intermediate plasma parameters. The plasma observations are described by A(sub p) = 0.85 beta(sub parallel P) (exp - 0.48) with a log regression coefficient of -0.74. This inverse A(sub p) - beta(sub parallel p) correlation corresponds closely to the isocontours of maximum ion anisotropy instability growth, gamma (sub m)/omega(sub p) = 0.01, for the mirror and cyclotron modes. The agreement of observed properties and predictions of local theory suggests that the spectral signatures reflect the local plasma environment and that the anisotropy instabilities regulate A(sub p). We suggest that the spectral characteristics may provide a useful basis for ordering observations in the magnetosheath and that the A(sub p) - beta(sub parallel p) inverse correlation may be used as a beta-dependent upper limit on the proton anisotropy to represent kinetic effects. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/20150004119','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20150004119">Survey of Coherent Approximately 1 Hz Waves in Mercury's Inner Magnetosphere from MESSENGER Observations</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Boardsen, Scott A.; Slavin, James A.; Anderson, Brian J.; Korth, Haje; Schriver, David; Solomon, Sean C. 2012-01-01 We summarize observations by the MESSENGER spacecraft of highly coherent waves at frequencies between 0.4 and 5 Hz in Mercury's inner magnetosphere. This survey covers the time period from 24 March to 25 September 2011, or 2.1 Mercury years. These waves typically exhibit banded harmonic structure that drifts in frequency as the spacecraft traverses the magnetic equator. The waves are seen at all magnetic local times, but their observed rate of occurrence is much less on the dayside, at least in part the result of MESSENGER's orbit. On the nightside, on average, wave power is maximum near the equator and decreases with increasing magnetic latitude, consistent with an equatorial source. When the spacecraft traverses the plasma sheet during its equatorial crossings, wave power is a factor of 2 larger than for equatorial crossings that do not cross the plasma sheet. The waves are highly transverse at large magnetic latitudes but are more compressional near the equator. However, at the equator the transverse component of these waves increases relative to the compressional component as the degree of polarization decreases. Also, there is a substantial minority of events that are transverse at all magnetic latitudes, including the equator. A few of these latter events could be interpreted as ion cyclotron waves. In general, the waves tend to be strongly linear and characterized by values of the ellipticity less than 0.3 and wave-normal angles peaked near 90 deg. Their maxima in wave power at the equator coupled with their narrow-band character suggests that these waves might be generated locally in loss cone plasma characterized by high values of the ratio beta of plasma pressure to magnetic pressure. Presumably both electromagnetic ion cyclotron waves and electromagnetic ion Bernstein waves can be generated by ion loss cone distributions. If proton beta decreases with increasing magnetic latitude along a field line, then electromagnetic ion Bernstein waves are predicted to transition from compressional to transverse, a pattern consistent with our observations. We hypothesize that these local instabilities can lead to enhanced ion precipitation and directly feed field-line resonances. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22600185-study-heat-flux-disruption-experimental-advanced-superconducting-tokamak','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22600185-study-heat-flux-disruption-experimental-advanced-superconducting-tokamak">The study of heat flux for disruption on experimental advanced superconducting tokamak</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Yang, Zhendong, E-mail: dongyz@ipp.ac.cn, E-mail: jafang@dhu.edu.cn; Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031; Fang, Jianan, E-mail: dongyz@ipp.ac.cn, E-mail: jafang@dhu.edu.cn Disruption of the plasma is one of the most dangerous instabilities in tokamak. During the disruption, most of the plasma thermal energy is lost, which causes damages to the plasma facing components. Infrared (IR) camera is an effective tool to detect the temperature distribution on the first wall, and the energy deposited on the first wall can be calculated from the surface temperature profile measured by the IR camera. This paper concentrates on the characteristics of heat flux distribution onto the first wall under different disruptions, including the minor disruption and the vertical displacement events (VDE) disruption. Several minor disruptionsmore » have been observed before the major disruption under the high plasma density in experimental advanced superconducting tokamak. During the minor disruption, the heat fluxes are mainly deposited on the upper/lower divertors. The magnetic configuration prior to the minor disruption is a lower single null with the radial distance between the two separatrices in the outer midplane dR{sub sep} = −2 cm, while it changes to upper single null (dR{sub sep} = 1.4 cm) during the minor disruption. As for the VDE disruption, the spatial distribution of heat flux exhibits strong toroidal and radial nonuniformity, and the maximum heat flux received on the dome plate can be up to 11 MW/m{sup 2}.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JAP...122p3303K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JAP...122p3303K">Detailed numerical simulation of cathode spots in vacuum arcs: Interplay of different mechanisms and ejection of droplets</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kaufmann, H. T. C.; Cunha, M. D.; Benilov, M. S.; Hartmann, W.; Wenzel, N. 2017-10-01 A model of cathode spots in high-current vacuum arcs is developed with account of all the potentially relevant mechanisms: the bombardment of the cathode surface by ions coming from a pre-existing plasma cloud; vaporization of the cathode material in the spot, its ionization, and the interaction of the produced plasma with the cathode; the Joule heat generation in the cathode body; melting of the cathode material and motion of the melt under the effect of the plasma pressure and the Lorentz force and related phenomena. After the spot has been ignited by the action of the cloud (which takes a few nanoseconds), the metal in the spot is melted and accelerated toward the periphery of the spot, with the main driving force being the pressure due to incident ions. Electron emission cooling and convective heat transfer are dominant mechanisms of cooling in the spot, limiting the maximum temperature of the cathode to approximately 4700-4800 K. A crater is formed on the cathode surface in this way. After the plasma cloud has been extinguished, a liquid-metal jet is formed and a droplet is ejected. No explosions have been observed. The modeling results conform to estimates of different mechanisms of cathode erosion derived from the experimental data on the net and ion erosion of copper cathodes. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018MPLB...3240018H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018MPLB...3240018H">Performance simulation of a plasma magnetohydrodynamic power generator</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Huang, Hulin; Li, Linyong; Zhu, Guiping 2018-05-01 The performance of magnetohydrodynamic (MHD) power generator is affected by many issues, among which the load coefficient k is of great importance. This paper reveals the relationship between the k and the performance of MHD generator by numerical simulation on Faraday-type MHD power generator using He/Xe as working plasma. The results demonstrate that the power generation efficiency increases with an increment of the load factor. However, the enthalpy extraction firstly increases then decreases with the load factor increasing. The enthalpy extraction rate reaches the maximum when the load coefficient k equals to 0.625, which infers the best performance of the power generator channel with the maximum electricity production. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010PSST...19d2001M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010PSST...19d2001M">BRIEF COMMUNICATION: The negative ion flux across a double sheath at the formation of a virtual cathode</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> McAdams, R.; Bacal, M. 2010-08-01 For the case of negative ions from a cathode entering a plasma, the maximum negative ion flux and the positive ion flux before the formation of a virtual cathode have been calculated for particular plasma conditions. The calculation is based on a simple modification of an analysis of electron emission into a plasma containing negative ions. The results are in good agreement with a 1d3v PIC code model. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014HEDP...11...30A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014HEDP...11...30A">Relativistically correct DD and DT neutron spectra</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Appelbe, B.; Chittenden, J. 2014-06-01 We use relativistic kinematics to derive an expression for the energy spectrum of neutrons produced by fusion reactions in deuterium and deuterium-tritium thermal plasmas. The derivation does not require approximations and the obtained expression gives the exact shape of the spectrum. It is shown that the high-energy tail of the neutron spectrum is highly sensitive to the plasma temperature. Simple expressions for the plasma temperature as a function of the neutron spectrum full width at half maximum (FWHM) are given. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018PhRvL.120g4801B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018PhRvL.120g4801B">Enhanced Laser-Driven Ion Acceleration by Superponderomotive Electrons Generated from Near-Critical-Density Plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Bin, J. H.; Yeung, M.; Gong, Z.; Wang, H. Y.; Kreuzer, C.; Zhou, M. L.; Streeter, M. J. V.; Foster, P. S.; Cousens, S.; Dromey, B.; Meyer-ter-Vehn, J.; Zepf, M.; Schreiber, J. 2018-02-01 We report on the experimental studies of laser driven ion acceleration from a double-layer target where a near-critical density target with a few-micron thickness is coated in front of a nanometer-thin diamondlike carbon foil. A significant enhancement of proton maximum energies from 12 to ˜30 MeV is observed when a relativistic laser pulse impinges on the double-layer target under linear polarization. We attributed the enhanced acceleration to superponderomotive electrons that were simultaneously measured in the experiments with energies far beyond the free-electron ponderomotive limit. Our interpretation is supported by two-dimensional simulation results. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011Cryo...51..225Z','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011Cryo...51..225Z">Study on industrial wastewater treatment using superconducting magnetic separation</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Zhang, Hao; Zhao, Zhengquan; Xu, Xiangdong; Li, Laifeng 2011-06-01 The mechanism of industrial wastewater treatment using superconducting magnetic separation is investigated. Fe 3O 4 nanoparticles were prepared by liquid precipitation and characterized by X-ray diffraction (XRD). Polyacrylic acid (PAA) film was coated on the magnetic particles using plasma coating technique. Transmission electron microscope (TEM) observation and infrared spectrum measurement indicate that the particle surface is well coated with PAA, and the film thickness is around 1 nm. Practical paper factory wastewater treatment using the modified magnetic seeds in a superconducting magnet (SCM) was carried out. The results show that the maximum removal rate of chemical oxygen demand (COD) by SCM method can reach 76%. </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active">23</li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_24" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active">24</li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="461"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011ApPhL..98n3702K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011ApPhL..98n3702K">Reactive hydroxyl radical-driven oral bacterial inactivation by radio frequency atmospheric plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kang, Sung Kil; Choi, Myeong Yeol; Koo, Il Gyo; Kim, Paul Y.; Kim, Yoonsun; Kim, Gon Jun; Mohamed, Abdel-Aleam H.; Collins, George J.; Lee, Jae Koo 2011-04-01 We demonstrated bacterial (Streptococcus mutans) inactivation by a radio frequency power driven atmospheric pressure plasma torch with H2O2 entrained in the feedstock gas. Optical emission spectroscopy identified substantial excited state •OH generation inside the plasma and relative •OH formation was verified by optical absorption. The bacterial inactivation rate increased with increasing •OH generation and reached a maximum 5-log10 reduction with 0.6% H2O2 vapor. Generation of large amounts of toxic ozone is drawback of plasma bacterial inactivation, thus it is significant that the ozone concentration falls within recommended safe allowable levels with addition of H2O2 vapor to the plasma. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1999PPCF...41..293V','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1999PPCF...41..293V">A titanium hydride gun for plasma injection into the T2-reversed field pinch device</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Voronin, A. V.; Hellblom, K. G. 1999-02-01 A study of a plasma gun (modified Bostic type) with titanium hydride electrodes has been carried out. The total number of released hydrogen atoms was in the range 1016-1018 and the maximum plasma flow velocity was 2.5×105 m s-1. The ion density near the gun edge reached 1.8×1020 m-3 and the electron temperature was around 40 eV as estimated from probe measurements. No species other than hydrogen or titanium were seen in the plasma line radiation. The plasma injector was successfully used for gas pre-ionization in the Extrap T2 reversed-field pinch device (ohmic heating toroidal experiment (OHTE)). </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27498100','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27498100">Pharmacokinetics, Pharmacodynamics and Population Pharmacokinetic/Pharmacodynamic Modelling of Bilastine, a Second-Generation Antihistamine, in Healthy Japanese Subjects.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Togawa, Michinori; Yamaya, Hidetoshi; Rodríguez, Mónica; Nagashima, Hirotaka 2016-12-01 Bilastine is a novel second-generation antihistamine for the symptomatic treatment of allergic rhinitis and urticaria. The objective of this study was to evaluate the pharmacokinetics, pharmacodynamics, and tolerability of bilastine following single and multiple oral doses in healthy Japanese subjects. The pharmacokinetic and pharmacodynamic profiles were compared with those reported in Caucasian subjects. In a single-blind, randomized, placebo-controlled, parallel-group, single- and multiple-ascending dose study, bilastine tablets were administered at single doses of 10, 20, and 50 mg (Part I), and once daily for 14 days at 20 and 50 mg (Part II). After single oral doses, maximum plasma concentrations (C max ) were reached at 1.0-1.5 h postdose. Plasma exposure [C max and area under the plasma concentration-time curve (AUC)] increased dose-proportionally at single doses of 10-50 mg. In repeated-dose administration, no remarkable differences were observed between Day 1 and Day 14 for C max or AUC. For inhibitory effects on wheal and flare response, bilastine 20 and 50 mg showed significant inhibition from 1.5 h after administration as compared with placebo, and the significant effect persisted for 24 h after administration. The rates of adverse events (AEs) were comparable between bilastine and placebo in both Part I and Part II. In addition, no dose- or administration period-dependent tendency of increase in rate of AEs or worsening of severity was observed. Bilastine exhibits similar single- and multiple-dose pharmacokinetic and pharmacodynamic characteristics in healthy Japanese subjects compared with those observed in Caucasian subjects in previous studies. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5440840','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5440840">Effect of Therapeutic Plasma Exchange on Immunoglobulins in Myasthenia Gravis</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Guptill, Jeffrey T.; Juel, Vern C.; Massey, Janice M.; Anderson, Amanda C.; Chopra, Manisha; Yi, John S.; Esfandiari, Ehsanollah; Buchanan, Tim; Smith, Bryan; Atherfold, Paul; Jones, Emma; Howard, James F. 2017-01-01 An integrated understanding of therapeutic plasma exchange (TPE) effects on immunoglobulins, autoantibodies, and natural or acquired (vaccine) protective antibodies in patients with autoimmune myasthenia gravis (MG) is lacking. Prior studies measured TPE effects in healthy volunteers or heterogeneous autoimmune diseases populations. We prospectively profiled plasma IgA, IgM, IgG, IgG subclasses (IgG1-4), acetylcholine receptor autoantibodies (AChR+), and protective antibodies in patients with AChR+ MG receiving TPE for an exacerbation. TPE was performed according to institutional practice and patients were profiled for up to 12 weeks. Ten patients were enrolled (median age=72.9 years; baseline MG-Composite=21; median TPE treatments=6 during their first course) and all improved. The maximum decrease in all immunoglobulins, including AChR autoantibodies, was achieved on the final day of the first TPE course (approximately 60–70% reduction). Three weeks post-TPE mean AChR autoantibody, total IgG, IgG1 and IgG2 titers were below the reference range and had not recovered to within 20% of baseline, whereas other measured immunoglobulins approached baseline values. We did not generally observe an “overshoot” of immunoglobulins above pre-TPE levels or accelerated recovery of pathologic AChR autoantibodies. Protective antibody profiles showed similar patterns as other IgGs and were detectable at levels associated with protection from infection. A slow return to baseline for IgGs (except IgG3) was observed, and we did not observe any obvious effect of concomitant medications on this recovery. Collectively, these findings enhance our understanding of the immunological effects of TPE and further supports the concept of rapid immunoglobulin depletion for the treatment of patients with MG. PMID:27684107 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27684107','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27684107">Effect of therapeutic plasma exchange on immunoglobulins in myasthenia gravis.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Guptill, Jeffrey T; Juel, Vern C; Massey, Janice M; Anderson, Amanda C; Chopra, Manisha; Yi, John S; Esfandiari, Ehsanollah; Buchanan, Tim; Smith, Bryan; Atherfold, Paul; Jones, Emma; Howard, James F 2016-11-01 An integrated understanding of therapeutic plasma exchange (TPE) effects on immunoglobulins, autoantibodies, and natural or acquired (vaccine) protective antibodies in patients with autoimmune myasthenia gravis (MG) is lacking. Prior studies measured TPE effects in healthy volunteers or heterogeneous autoimmune disease populations. We prospectively profiled plasma IgA, IgM, IgG, IgG subclasses (IgG1-4), acetylcholine receptor autoantibodies (AChR+), and protective antibodies in patients with AChR + MG receiving TPE for an exacerbation. TPE was performed according to institutional practice and patients were profiled for up to 12 weeks. Ten patients were enrolled (median age = 72.9 years; baseline MG-Composite = 21; median TPE treatments = 6 during their first course) and all improved. The maximum decrease in all immunoglobulins, including AChR autoantibodies, was achieved on the final day of the first TPE course (∼60-70% reduction). Three weeks post-TPE, mean AChR autoantibody, total IgG, IgG1, and IgG2 titers were below the reference range and had not recovered within 20% of baseline, whereas other measured immunoglobulins approached baseline values. We did not generally observe an "overshoot" of immunoglobulins above pre-TPE levels or accelerated recovery of pathologic AChR autoantibodies. Protective antibody profiles showed similar patterns as other IgGs and were detectable at levels associated with protection from infection. A slow return to baseline for IgGs (except IgG3) was observed, and we did not observe any obvious effect of concomitant medications on this recovery. Collectively, these findings enhance our understanding of the immunological effects of TPE and further support the concept of rapid immunoglobulin depletion for the treatment of patients with MG. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29038350','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29038350">Male apoE*3-Leiden.CETP mice on high-fat high-cholesterol diet exhibit a biphasic dyslipidemic response, mimicking the changes in plasma lipids observed through life in men.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Paalvast, Yared; Gerding, Albert; Wang, Yanan; Bloks, Vincent W; van Dijk, Theo H; Havinga, Rick; Willems van Dijk, Ko; Rensen, Patrick C N; Bakker, Barbara M; Kuivenhoven, Jan Albert; Groen, Albert K 2017-10-01 Physiological adaptations resulting in the development of the metabolic syndrome in man occur over a time span of several decades. This combined with the prohibitive financial cost and ethical concerns to measure key metabolic parameters repeatedly in subjects for the major part of their life span makes that comprehensive longitudinal human data sets are virtually nonexistent. While experimental mice are often used, little is known whether this species is in fact an adequate model to better understand the mechanisms that drive the metabolic syndrome in man. We took up the challenge to study the response of male apoE*3-Leiden.CETP mice (with a humanized lipid profile) to a high-fat high-cholesterol diet for 6 months. Study parameters include body weight, food intake, plasma and liver lipids, hepatic transcriptome, VLDL - triglyceride production and importantly the use of stable isotopes to measure hepatic de novo lipogenesis, gluconeogenesis, and biliary/fecal sterol secretion to assess metabolic fluxes. The key observations include (1) high inter-individual variation; (2) a largely unaffected hepatic transcriptome at 2, 3, and 6 months; (3) a biphasic response curve of the main metabolic features over time; and (4) maximum insulin resistance preceding dyslipidemia. The biphasic response in plasma triglyceride and total cholesterol appears to mimic that of men in cross-sectional studies. Combined, these observations suggest that studies such as these can help to delineate the causes of metabolic derangements in patients suffering from metabolic syndrome. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22663584-blob-formation-ejection-coronal-jets-due-plasmoid-kelvinhelmholtz-instabilities','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22663584-blob-formation-ejection-coronal-jets-due-plasmoid-kelvinhelmholtz-instabilities">Blob Formation and Ejection in Coronal Jets due to the Plasmoid and Kelvin–Helmholtz Instabilities</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Ni, Lei; Lin, Jun; Zhang, Qing-Min 2017-05-20 We perform 2D resistive magnetohydrodynamic simulations of coronal jets driven by flux emergence along the lower boundary. The reconnection layers are susceptible to the formation of blobs that are ejected in the jet. Our simulation with low plasma β (Case I) shows that magnetic islands form easily and propagate upward in the jet. These islands are multithermal and thus are predicted to show up in hot channels (335 Å and 211 Å) and the cool channel (304 Å) in observations by the Atmospheric Imaging Assembly (AIA) on the Solar Dynamics Observatory . The islands have maximum temperatures of 8 MK,more » lifetimes of 120 s, diameters of 6 Mm, and velocities of 200 km s{sup −1}. These parameters are similar to the properties of blobs observed in extreme-ultraviolet (EUV) jets by AIA. The Kelvin–Helmholtz instability develops in our simulation with moderately high plasma β (Case II) and leads to the formation of bright vortex-like blobs above the multiple high magnetosonic Mach number regions that appear along the jet. These vortex-like blobs can also be identified in the AIA channels. However, they eventually move downward and disappear after the high magnetosonic Mach number regions disappear. In the lower plasma β case, the lifetime for the jet is shorter, the jet and magnetic islands are formed with higher velocities and temperatures, the current-sheet fragments are more chaotic, and more magnetic islands are generated. Our results show that the plasmoid instability and Kelvin–Helmholtz instability along the jet are both possible causes of the formation of blobs observed at EUV wavelengths.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017PhPl...24h3112A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017PhPl...24h3112A">Optical emission spectroscopy of magnetically confined laser induced vanadium pentoxide (V2O5) plasma</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Amin, Saba; Bashir, Shazia; Anjum, Safia; Akram, Mahreen; Hayat, Asma; Waheed, Sadia; Iftikhar, Hina; Dawood, Assadullah; Mahmood, Khaliq 2017-08-01 Optical emission spectra of a laser induced plasma of vanadium pentoxide (V2O5) using a Nd:YAG laser (1064 nm, 10 ns) in the presence and absence of the magnetic field of 0.45 T have been investigated. The effect of the magnetic field (B) on the V2O5 plasma at various laser irradiances ranging from 0.64 GW cm-2 to 2.56 GW cm-2 is investigated while keeping the pressure of environmental gases of Ar and Ne constant at 100 Torr. The magnetic field effect on plasma parameters of V2O5 is also explored at different delay times ranging from 0 μs to 10 μs for both environmental gases of Ar and Ne at the laser irradiance of 1.28 GW cm-2. It is revealed that both the emission intensity and electron temperature of the vanadium pentoxide plasma initially increase with increasing irradiance due to the enhanced energy deposition and mass ablation rate. After achieving a certain maximum, both exhibit a decreasing trend or saturation which is attributable to the plasma shielding effect. However, the electron density shows a decreasing trend with increasing laser irradiance. This trend remains the same for both cases, i.e., in the presence and in the absence of magnetic field and for both background gases of Ar and Ne. However, it is revealed that both the electron temperature and electron density of the V2O5 plasma are significantly enhanced in the presence of the magnetic field for both environments at all laser irradiances and delay times, and more pronounced effects are observed at higher irradiances. The enhancement in plasma parameters is attributed to the confinement as well as Joule heating effects caused by magnetic field employment. The confinement of the plasma is also confirmed by the analytically calculated value of magnetic pressure β, which is smaller than plasma pressure at all irradiances and delay times, and therefore confirms the validity of magnetic confinement of the V2O5 plasma. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/10333083','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/10333083">Calcium homeostasis during oral glucose load in healthy women.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> D'Erasmo, E; Pisani, D; Ragno, A; Raejntroph, N; Vecci, E; Acca, M 1999-04-01 It has been demonstrated that in healthy subjects during oral glucose tolerance test, serum calcium declines, while urinary calcium excretion increases, even if there is not a general agreement in this regard. The study was carried out in order to evaluate the effects of glucose oral load on calcium homeostasis in eight healthy adult women, also considering ionized calcium, plasma insulin and parathyroid hormone changes. The results showed a decline of total and ionized serum calcium (p < 0.05 and p < 0.01, respectively; maximum of the decrease at time 120'), in parallel with the increase of urinary calcium/ creatinine ratio (p < 0.05). Serum glucose and insulin increase (p < 0.0001 and p < 0.0005 respectively; maximum value at time 60'), while the parathyroid hormone level decreases (maximum decline at time 120', p < 0.01). No changes were observed in fasting control subjects for all parameters considered. The changes of these parameters with time suggest that the effects of glucose oral load on calcium metabolism in healthy adult women may be the consequence of parathyroid hormone suppression induced by acute hyperglycemia/hyperinsulinemia. The results confirm in vivo the PTH behaviour in vitro, on cultured bovine parathyroid cells, with high glucose concentration. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19730046545&hterms=PH+test&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3DPH%2Btest','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19730046545&hterms=PH+test&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3DPH%2Btest">Plasma electrolytes, pH, and ECG during and after exhaustive exercise.</a> <a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a> Coester, N.; Elliott, J. C.; Luft, U. C. 1973-01-01 Ten men worked on a bicycle ergometer at increasing work loads to exhaustion in 15 min. Each performed one test breathing air and another with added CO2 in random sequence. ECG was recorded during exercise and for 30 min of recovery. Arterial samples for blood gases, pH, and electrolytes were drawn at rest, in the last minute of exercise and at 1, 4, 10, 20, and 30 min thereafter. A striking increase in the amplitude of T and P waves was observed reaching a maximum in the first 2 min after exercise. All electrolytes measured were increased at the end of exercise, most markedly potassium (60%) and phosphorus (53%). Potassium dropped faster than all others to below resting values in 4 min coinciding with the lowest levels in plasma bicarbonate. ECG alterations were not closely related in time with any single factor such as potassium, but appeared to reflect an interaction of the transient mineral and acid-base imbalance during and immediately following exhaustive exercise. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/11768437','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/11768437">Characteristics of healthy population among the migrants to the North.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Leutin, V P 2001-11-01 The goal of the study was to elucidate psychophysiological characteristics of subjects who can adapt effectively to Arctic and Subarctic conditions. Plasma cortisol and insulin levels, blood pressure as well as functional sensori-motor asymmetry have been examined in the groups of North Selkups and transit workers from the Subarctic regions. The highest level of plasma cortisol was observed in the Selkups with the predominance of the right indices of sensorimotor asymmetry, whereas the lowest cortisol concentrations have been found in the left-handed groups. The level of insulin appeared to be lower in all examined groups of the Selkups. No changes in the blood pressure were found among the northern populations. The maximum incidence of arterial hypertension was revealed among shift workers with the predominance of the right profile of functional asymmetry. The indices of functional asymmetry, giving important information about adaptive abilities of different populations to severe climato-geographical conditions, can be a useful prognostic factor for the professional selection of workers in the North regions. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018NucFu..58d6009L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018NucFu..58d6009L">Study of ion-gyroscale fluctuations in low-density L-mode plasmas heated by NBI on KSTAR</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Lee, W.; Ko, S. H.; Leem, J.; Yun, G. S.; Park, H. K.; Wang, W. X.; Budny, R. V.; Kim, K. W.; Luhmann, N. C., Jr.; The KSTAR Team 2018-04-01 Broadband density fluctuations with peak frequency ranging from 150 to 400 kHz were measured using a multichannel microwave imaging reflectometer in core region of the low-density L-mode plasmas heated by neutral beam injection on KSTAR. These fluctuations have been studied by comparing the dominant mode scales estimated from the measurement with those predicted from linear gyrokinetic simulation. The measured poloidal wavenumbers are qualitatively comparable to those of the ‘fastest growing modes’ from simulations, whereas they are larger than those of the ‘transport-dominant modes’ by about a factor of three. The agreement on wavenumbers between the measurement and linear simulation (for the fastest growing modes) is probably due to sufficiently weak E × B flow shear compared to the maximum linear growth rate. Meanwhile, the transport-dominant modes seem to be related to the fluctuations in lower frequencies (˜80-150 kHz) observed in some of the measurement. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5456023','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5456023">Effect of Spark Plasma Sintering on the Structure and Properties of Ti1−xZrxNiSn Half-Heusler Alloys</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Downie, Ruth A.; Popuri, Srinivas R.; Ning, Huanpo; Reece, Mike J.; Bos, Jan-Willem G. 2014-01-01 XNiSn (X = Ti, Zr and Hf) half-Heusler alloys have promising thermoelectric properties and are attracting enormous interest for use in waste heat recovery. In particular, multiphase behaviour has been linked to reduced lattice thermal conductivities, which enables improved energy conversion efficiencies. This manuscript describes the impact of spark plasma sintering (SPS) on the phase distributions and thermoelectric properties of Ti0.5Zr0.5NiSn based half-Heuslers. Rietveld analysis reveals small changes in composition, while measurement of the Seebeck coefficient and electrical resistivities reveals that all SPS treated samples are electron doped compared to the as-prepared samples. The lattice thermal conductivities fall between 4 W·m−1·K−1 at 350 K and 3 W·m−1·K−1 at 740 K. A maximum ZT = 0.7 at 740 K is observed in a sample with nominal Ti0.5Zr0.5NiSn composition. PMID:28788234 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22342140-ray-flare-from-cas','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22342140-ray-flare-from-cas">An X-ray flare from 47 Cas</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Pandey, Jeewan C.; Karmakar, Subhajeet, E-mail: jeewan@aries.res.in 2015-02-01 Using XMM-Newton observations, we investigate properties of a flare from the very active but poorly known stellar system 47 Cas. The luminosity at the peak of the flare is found to be 3.54 × 10{sup 30} erg s{sup −1}, which is ∼2 times higher than that at a quiescent state. The quiescent state corona of 47 Cas can be represented by two temperature plasma: 3.7 and 11.0 MK. The time-resolved X-ray spectroscopy of the flare show the variable nature of the temperature, the emission measure, and the abundance. The maximum temperature during the flare is derived as 72.8 MK. Wemore » infer the length of a flaring loop to be 3.3 × 10{sup 10} cm using a hydrodynamic loop model. Using the RGS spectra, the density during the flare is estimated as 4.0 × 10{sup 10} cm{sup −3}. The loop scaling laws are also applied when deriving physical parameters of the flaring plasma.« less </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28645069','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28645069">Controlled single bubble cavitation collapse results in jet-induced injury in brain tissue.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Canchi, Saranya; Kelly, Karen; Hong, Yu; King, Michael A; Subhash, Ghatu; Sarntinoranont, Malisa 2017-10-01 Multiscale damage due to cavitation is considered as a potential mechanism of traumatic brain injury (TBI) associated with explosion. In this study, we employed a TBI relevant hippocampal ex vivo slice model to induce bubble cavitation. Placement of single reproducible seed bubbles allowed control of size, number, and tissue location to visualize and measure deformation parameters. Maximum strain value was measured at 45 µs after bubble collapse, presented with a distinct contour and coincided temporally and spatially with the liquid jet. Composite injury maps combined this maximum strain value with maximum measured bubble size and location along with histological injury patterns. This facilitated the correlation of bubble location and subsequent jet direction to the corresponding regions of high strain which overlapped with regions of observed injury. A dynamic threshold strain range for tearing of cerebral cortex was estimated to be between 0.5 and 0.6. For a seed bubble placed underneath the hippocampus, cavitation induced damage was observed in hippocampus (local), proximal cerebral cortex (marginal) and the midbrain/forebrain (remote) upon histological evaluation. Within this test model, zone of cavitation injury was greater than the maximum radius of the bubble. Separation of apposed structures, tissue tearing, and disruption of cellular layers defined early injury patterns that were not detected in the blast-exposed half of the brain slice. Ultrastructural pathology of the neurons exposed to cavitation was characterized by disintegration of plasma membrane along with loss of cellular content. The developed test system provided a controlled experimental platform to study cavitation induced high strain deformations on brain tissue slice. The goal of the future studies will be to lower underpressure magnitude and cavitation bubble size for more sensitive evaluation of injury. Copyright © 2017 Elsevier Ltd. All rights reserved. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28693047','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28693047">Thermal Effect of J-Plasma® Energy in a Porcine Tissue Model: Implications for Minimally Invasive Surgery.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Pedroso, Jasmine D; Gutierrez, Melissa M; Volker, K Warren; Howard, David L 2017-07-25 To evaluate tissue effect of J-Plasma® (Bovie Medical Corporation, Clearwater, Florida) in porcine liver, kidney, muscle, ovarian, and uterine tissue blocks. Prospective study utilizing porcine tissue blocks to evaluate the thermal spread of J-Plasma® device on liver, kidney, muscle, ovarian, and uterine tissue at various power settings, gas flow, and exposure times. J-Plasma® helium was used in porcine liver, kidney, and muscle tissue at 20%, 50%, and 100% power, and 1 L/min, 3 L/min, and 5 L/min gas flow at one, five, and 10-second intervals. J-Plasma® was then used in ovarian and uterine tissue at maximum power and gas flow settings in intervals of one, five, 10, and 30 seconds. Histologic evaluation of each tissue was then performed to measure thermal spread. Regardless of tissue type, increased power setting, gas flow rate, and exposure time correlated with greater depth of thermal spread in liver, kidney, and muscle tissue. J-Plasma® did not exceed 2 mm thermal spread on liver, kidney, muscle, ovarian, and uterine tissue, even at a maximum setting of 100% power and 5 L/min gas flow after five seconds. Prolonged exposure to J-Plasma® of up to 30 seconds resulted in increased length and width of thermal spread of up to 12 mm, but did not result in significantly increased depth at 2.84 mm. The J-Plasma® helium device has minimal lateral and depth of thermal spread in a variety of tissue types and can likely be used for a multitude of gynecologic surgical procedures. However, further studies are needed to demonstrate device safety in a clinical setting. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2005JPFR...81..204R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2005JPFR...81..204R">Efficient Radio Frequency Inductive Discharges in Near Atmospheric Pressure Using Immittance Conversion Topology</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Razzak, M. Abdur; Takamura, Shuichi; Uesugi, Yoshihiko; Ohno, Noriyasu A radio frequency (rf) inductive discharge in atmospheric pressure range requires high voltage in the initial startup phase and high power during the steady state sustainment phase. It is, therefore, necessary to inject high rf power into the plasma ensuring the maximum use of the power source, especially where the rf power is limited. In order to inject the maximum possible rf power into the plasma with a moderate rf power source of few kilowatts range, we employ the immittance conversion topology by converting a constant voltage source into a constant current source to generate efficient rf discharge by inductively coupled plasma (ICP) technique at a gas pressure with up to one atmosphere in argon. A novel T-LCL immittance circuit is designed for constant-current high-power operation, which is practically very important in the high-frequency range, to provide high effective rf power to the plasma. The immittance conversion system combines the static induction transistor (SIT)-based radio frequency (rf) high-power inverter circuit and the immittance conversion elements including the rf induction coil. The basic properties of the immittance circuit are studied by numerical analysis and verified the results by experimental measurements with the inductive plasma as a load at a relatively high rf power of about 4 kW. The performances of the immittance circuit are also evaluated and compared with that of the conventional series resonance circuit in high-pressure induction plasma generation. The experimental results reveal that the immittance conversion circuit confirms injecting higher effective rf power into the plasma as much as three times than that of the series resonance circuit under the same operating conditions and same dc supply voltage to the inverter, thereby enhancing the plasma heating efficiency to generate efficient rf inductive discharges. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/8454171','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/8454171">Biological activity of alligator, avian, and mammalian insulin in juvenile alligators: plasma glucose and amino acids.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Lance, V A; Elsey, R M; Coulson, R A 1993-02-01 The biological activity of alligator, turkey, and bovine insulin on plasma glucose and plasma amino acids was tested in fasted juvenile alligators. Preliminary experiments showed that the stress associated with taking the initial blood sample resulted in a hyperglycemic response lasting more than 24 hr. Despite repeated bleedings no additional hyperglycemic events occurred, and blood glucose declined slowly over the next 7 days. Under these conditions the smallest dose of insulin eliciting a hypoglycemic response was 40 micrograms/kg body wt. A dose of 400 micrograms/kg body wt of either alligator or bovine insulin caused a pronounced hypoglycemia by 12 hr postinjection. Maximum decline in plasma glucose occurred at 24 to 36 hr with a slow return to control levels by 120 hr. There were no significant differences in the hypoglycemic responses to any of the three insulins tested. The decline in plasma amino acids was much more rapid than the decline in plasma glucose in response to insulin. Even at the 40 micrograms/kg body wt dose a significant difference from saline-injected control was seen at 2 hr postinjection. Maximum decline in plasma amino acids occurred at 8 to 12 hr with a return to baseline by 36 hr. These results show that the relatively conservative changes in the sequence of alligator insulin (three amino acid substitutions in the B-chain compared with that of chicken) have little effect on biological activity and that alligator insulin receptors do not appear to discriminate among the three insulins. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018PlST...20a4022D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018PlST...20a4022D">Temporal and spatial dynamics of optical emission from laser ablation of the first wall materials of fusion device</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Dongye, ZHAO; Cong, LI; Yong, WANG; Zhiwei, WANG; Liang, GAO; Zhenhua, HU; Jing, WU; Guang-Nan, LUO; Hongbin, DING 2018-01-01 Laser-induced breakdown spectroscopy (LIBS) has been developed to in situ diagnose the chemical compositions of the first wall in the EAST tokamak. However, the dynamics of optical emission of the key plasma-facing materials, such as tungsten, molybdenum and graphite have not been investigated in a laser produced plasma (LPP) under vacuum. In this work, the temporal and spatial dynamics of optical emission were investigated using the spectrometer with ICCD. Plasma was produced by an Nd:YAG laser (1064 nm) with pulse duration of 6 ns. The results showed that the typical lifetime of LPP is less than 1.4 μs, and the lifetime of ions is shorter than atoms at ˜10-6 mbar. Temporal features of optical emission showed that the optimized delay times for collecting spectra are from 100 to 400 ns which depended on the corresponding species. For spatial distribution, the maximum LIBS spectral intensity in plasma plume is obtained in the region from 1.5 to 3.0 mm above the sample surface. Moreover, the plasma expansion velocity involving the different species in a multicomponent system was measured for obtaining the proper timing (gate delay time and gate width) of the maximum emission intensity and for understanding the plasma expansion mechanism. The order of expansion velocities for various species is {V}{{{C}}+}> {V}{{H}}> {V}{{{Si}}+}> {V}{{Li}}> {V}{{Mo}}> {V}{{W}}. These results could be attributed to the plasma sheath acceleration and mass effect. In addition, an optimum signal-to-background ratio was investigated by varying both delay time and detecting position. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16513299','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16513299">Toxicokinetics of lambda-cyhalothrin in rats.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Anadón, A; Martínez, M; Martínez, M A; Díaz, M J; Martínez-Larrañaga, M R 2006-08-01 The toxicokinetics of lambda-cyhalothrin after single 20 mg kg(-1) oral and 3 mg kg(-1) intravenous doses were studied in rats. Serial blood samples were obtained after oral and intravenous administration. Liver, brain, spinal cord, sciatic nerve, vas deferens, anococcygeus and myenteric plexus tissue samples were also collected. Plasma, liver, hypothalamus, cerebellum, medulla oblongata, frontal cortex, striatum, hippocampus, midbrain, spinal cord, vas deferens, anococcygeus, myenteric plexus and sciatic nerve concentrations of lambda-cyhalothrin were determined by HPLC. The plasma and tissue concentration-time data for lambda-cyhalothrin were found to fit a two-compartment open model. For lambda-cyhalothrin, the elimination half-life (T1/2beta) and the mean residence time from plasma were 7.55 and 8.55 h after i.v. and 10.27 and 14.43 h after oral administration. The total plasma clearance was not influenced by dose concentration or route and reached a value of 0.060l h(-1)kg(-1). After i.v. administration, the apparent volume of distribution and at steady state were 0.68 and 0.53l kg(-1), suggesting a diffusion of the pyrethroid into tissue. After oral administration, lambda-cyhalothrin was extensively but slowly absorbed (Tmax, 2.69 h). The oral bioavailability was found to be 67.37%. Significant differences in the kinetic parameters between nervous tissues and plasma was observed. The maximum concentrations in hypothalamus (Cmax, 24.12 microg g(-1)) and myenteric plexus (Cmax, 25.12 microg g(-1)) were about 1.5 times higher than in plasma (Cmax, 15.65 microg ml(-1)) and 1.3 times higher than in liver (Cmax, 18.42 microg ml(-1)). Nervous tissue accumulation of lambda-cyhalothrin was also reflected by the area under the concentration curve ratios of tissue/plasma (liver). The T1/2beta for lambda-cyhalothrin was significantly greater for the nerve tissues, including neuromuscular fibres, (range 12-26 and 15-34 h, after i.v. and oral doses) than for plasma (7.55 and 10.27 h, respectively). </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active">24</li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> </div> <div id="page_25" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active">25</li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="481"> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017NucFu..57k6027I','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017NucFu..57k6027I">MHD limits and plasma response in high-beta hybrid operations in ASDEX Upgrade</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Igochine, V.; Piovesan, P.; Classen, I. G. J.; Dunne, M.; Gude, A.; Lauber, P.; Liu, Y.; Maraschek, M.; Marrelli, L.; McDermott, R.; Reich, M.; Ryan, D.; Schneller, M.; Strumberger, E.; Suttrop, W.; Tardini, G.; Zohm, H.; The ASDEX Upgrade Team; The EUROfusion MST1 Team 2017-11-01 The improved H-mode scenario (or high β hybrid operations) is one of the main candidates for high-fusion performance tokamak operation that offers a potential steady-state scenario. In this case, the normalized pressure {{β }N} must be maximized and pressure-driven instabilities will limit the plasma performance. These instabilities could have either resistive ((m = 2, n = 1) and (3,2) neoclassical tearing modes (NTMs)) or ideal character (n = 1 ideal kink mode). In ASDEX Upgrade (AUG), the first limit for maximum achievable {{β }N} is set by the NTMs. The application of pre-emptive electron cyclotron current drive at the q = 2 and q = 1.5 resonant surfaces reduces this problem, so that higher values of {{β }N} can be reached. AUG experiments have shown that, in spite of the fact that hybrids are mainly limited by NTMs, the proximity to the no-wall limit leads to amplification of the external fields that strongly influence the plasma profiles. For example, rotation braking is observed throughout the plasma and peaks in the core. In this situation, even small external fields are amplified and their effect becomes visible. To quantify these effects, the plasma response to the magnetic fields produced by B-coils is measured as {{β }N} approaches the no-wall limit. These experiments and corresponding modeling allow the identification of the main limiting factors, which depend on the stabilizing influence of the conducting components facing the plasma surface, the existence of external actuators, and the kinetic interaction between the plasma and the marginally stable ideal modes. Analysis of the plasma reaction to external perturbations allowed us to identify optimal correction currents for compensating the intrinsic error field in the device. Such correction, together with the analysis of kinetic effects, will help to increase {{β }N} further in future experiments. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27645396','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27645396">Plasma Skimming in a Spiral Groove Bearing of a Centrifugal Blood Pump.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Murashige, Tomotaka; Sakota, Daisuke; Kosaka, Ryo; Nishida, Masahiro; Kawaguchi, Yasuo; Yamane, Takashi; Maruyama, Osamu 2016-09-01 Plasma skimming is a phenomenon in which discharge hematocrit is lower than feed hematocrit in microvessels. Plasma skimming has been investigated at a bearing gap in a spiral groove bearing (SGB), as this has the potential to prevent hemolysis in the SGB of a blood pump. However, it is not clear whether plasma skimming occurs in a blood pump with the SGB, because the hematocrit has not been obtained. The purpose of this study is to verify plasma skimming in an SGB of a centrifugal blood pump by developing a hematocrit measurement method in an SGB. Erythrocyte observation using a high-speed microscope and a bearing gap measurement using a laser confocal displacement meter was performed five times. In these tests, bovine blood as a working fluid was diluted with autologous plasma to adjust the hematocrit to 1.0%. A resistor was adjusted to achieve a pressure head of 100 mm Hg and a flow rate of 5.0 L/min at a rotational speed of 2800 rpm. Hematocrit on the ridge region in the SGB was measured using an image analysis based on motion image of erythrocytes, mean corpuscular volume, the measured bearing gap, and a cross-sectional area of erythrocyte. Mean hematocrit on the ridge region in the SGB was linearly reduced from 0.97 to 0.07% with the decreasing mean bearing gap from 38 to 21 μm when the rotational speed was changed from 2250 to 3000 rpm. A maximum plasma skimming efficiency of 93% was obtained with a gap of 21 μm. In conclusion, we succeeded in measuring the hematocrit on the ridge region in the SGB of the blood pump. Hematocrit decreased on the ridge region in the SGB and plasma skimming occurred with a bearing gap of less than 30 μm in the hydrodynamically levitated centrifugal blood pump. © 2016 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3362497','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3362497">Correlation between plasma concentration ratios of SN-38 glucuronide and SN-38 and neutropenia induction in patients with colorectal cancer and wild-type UGT1A1 gene</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> HIROSE, KOICHI; KOZU, CHIHIRO; YAMASHITA, KOSHIRO; MARUO, EIJI; KITAMURA, MIZUHO; HASEGAWA, JUNICHI; OMODA, KEI; MURAKAMI, TERUO; MAEDA, YORINOBU 2011-01-01 In irinotecan (CPT-11)-based chemotherapy, neutropenia and diarrhea are often induced. In the present study, the clinical significance of the concentration ratios of 7-ethyl-10-hydroxycamptothecin (SN-38) glucuronide (SN-38G) and SN-38 in the plasma in predicting CPT-11-induced neutropenia was examined. A total of 17 patients with colorectal cancer and wild-type UDP-glucuronosyltransferase (UGT)1A1 gene were enrolled and treated with CPT-11 as part of the FOLFIRI regimen [CPT-11 and fluorouracil (5-FU)]. Blood was taken exactly 15 min following a 2-h continuous infusion of CPT-11. Plasma concentrations of SN-38, SN-38G and CPT-11 were determined by a modified high-performance liquid chromatography (HPLC) method. The median, maximum and minimum values of plasma SN-38G/SN-38 ratios were 4.25, 7.09 and 1.03, respectively, indicating that UGT activities are variable among patients with the wild-type UGT1A1 gene. The plasma SN-38G/SN-38 ratios decreased with an increase in the trial numbers of chemotherapy (r=0.741, p=0.000669), suggesting that CPT-11 treatment suppresses UGT activity, and the low plasma SN-38G/SN-38 ratios resulted in the induction of greater neutropenia. However, in this analysis, 2 clearly separated regression lines were observed between plasma SN-38G/SN-38 ratios and neutropenia induction. In conclusion, UGT activity involved in SN-38 metabolism is variable among patients with the wild-type UGT1A1 gene, and each CPT-11 treatment suppresses UGT activity. One-point determination of the plasma SN-38G/SN-38 ratio may provide indications for the prediction of CPT-11-induced neutropenia and adjustment of the optimal dose, although further studies are required. PMID:22740978 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1993JGR....98.6013D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1993JGR....98.6013D">Dual-mode E region plasma wave observations from Millstone Hill</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> del Pozo, C. F.; Foster, J. C.; St.-Maurice, J.-P. 1993-04-01 Observations and analysis of the unstable auroral E region during local afternoon to early morning hours, and modified two-stream waves as well as two kinds of waves associated with the turbulence created by such waves are identified. One of these types exhibits properties similar to those of type II waves reported in the literature, whereas the second type has a broader spectrum, is detected in all directions, and appears to be new. The onset of turbulence corresponds to an electric field threshold of the order of 20 m/Vm. The presence of an azimuthal asymmetry in both the threshold field and the observed phase velocities with systematically greater values is detected; they are attributed to the presence of a 50-m/s E-W neutral wind at E region heights. The maximum observed volume reflectivity for type I wave ranges exceeded 10 exp -11, and that of the secondaries was of the order of 20 dB smaller. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/10493596','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/10493596">Uptake and depletion of plasma 17alpha-methyltestosterone during induction of masculinization in muskellunge, Esox masquinongy: effect on plasma steroids and sex reversal.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Rinchard, J; Dabrowski, K; Garcia-Abiado, M A; Ottobre, J 1999-08-01 Oral administration of 17alpha-methyltestosterone (MT) was used to induce masculinization of sexually undifferentiated muskellunge, Esox masquinongy. Three groups of muskellunge (mean weight, 2.5 +/- 0.6 g) were submitted to MT treatment (15 mg of MT/kg) for 60 days. An additional one group was used as a control (hormone-free diet). Food was distributed over a 10-h period by using automatic belt feeders. Blood was sampled in both control and treated fish at different intervals during and after feeding: before (0 h), at 3 h, 6 h, and cessation of feeding (10 h), and after a fast of 22 h (32 h). MT had no significant effect on growth and survival in muskellunge 6 months after the treatment. Concentrations of plasma MT increased during the feeding period and reached their maximum levels 6 or 10 h after starting feeding. This rapid increase of MT indicated a rapid absorption of this steroid. Plasma MT levels then declined and reached a radir by 22 h after cessation of feeding, suggesting that MT is rapidly metabolized and excreted. The profiles of plasma testosterone during the MT treatment did not differ significantly between control and MT-treated groups. During and after the MT treatment, the concentration of plasma testosterone did not differ significantly between control and MT-treated groups. Moreover, no sexual dimorphism of testosterone levels was observed. Six months after treatment, the sex ratio in MT-treated groups (33% males, 62% females, and 5% intersex) was opposite to control (70% and 30%, respectively) and differed significantly. This suggests that at 15 mg of MT/kg over 60 days, a paradoxical feminization took place. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25256240','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25256240">Controlling the misuse of cobalt in horses.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Ho, Emmie N M; Chan, George H M; Wan, Terence S M; Curl, Peter; Riggs, Christopher M; Hurley, Michael J; Sykes, David 2015-01-01 Cobalt is a well-established inducer of hypoxia-like responses, which can cause gene modulation at the hypoxia inducible factor pathway to induce erythropoietin transcription. Cobalt salts are orally active, inexpensive, and easily accessible. It is an attractive blood doping agent for enhancing aerobic performance. Indeed, recent intelligence and investigations have confirmed cobalt was being abused in equine sports. In this paper, population surveys of total cobalt in raceday samples were conducted using inductively coupled plasma mass spectrometry (ICP-MS). Urinary threshold of 75 ng/mL and plasma threshold of 2 ng/mL could be proposed for the control of cobalt misuse in raceday or in-competition samples. Results from administration trials with cobalt-containing supplements showed that common supplements could elevate urinary and plasma cobalt levels above the proposed thresholds within 24 h of administration. It would therefore be necessary to ban the use of cobalt-containing supplements on raceday as well as on the day before racing in order to implement and enforce the proposed thresholds. Since the abuse with huge quantities of cobalt salts can be done during training while the use of legitimate cobalt-containing supplements are also allowed, different urinary and plasma cobalt thresholds would be required to control cobalt abuse in non-raceday or out-of-competition samples. This could be achieved by setting the thresholds above the maximum urinary and plasma cobalt concentrations observed or anticipated from the normal use of legitimate cobalt-containing supplements. Urinary threshold of 2000 ng/mL and plasma threshold of 10 ng/mL were thus proposed for the control of cobalt abuse in non-raceday or out-of-competition samples. Copyright © 2014 John Wiley & Sons, Ltd. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017ApJ...841...47B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017ApJ...841...47B">Transition from the Unipolar Region to the Sector Zone: Voyager 2, 2013 and 2014</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Burlaga, L. F.; Ness, N. F.; Richardson, J. D. 2017-05-01 We discuss magnetic field and plasma observations of the heliosheath made by Voyager 2 (V2) during 2013 and 2014 near solar maximum. A transition from a unipolar region to a sector zone was observed in the azimuthal angle λ between ˜2012.45 and 2013.82. The distribution of λ was strongly singly peaked at 270^\\circ in the unipolar region and double peaked in the sector zone. The δ-distribution was strongly peaked in the unipolar region and very broad in the sector zone. The distribution of daily averages of the magnetic field strength B was Gaussian in the unipolar region and lognormal in the sector zone. The correlation function of B was exponential with an e-folding time of ˜5 days in both regions. The distribution of hourly increments of B was a Tsallis distribution with nonextensivity parameter q = 1.7 ± 0.04 in the unipolar region and q = 1.44 ± 0.12 in the sector zone. The CR-B relationship qualitatively describes the 2013 observations, but not the 2014 observations. A 40 km s-1 increase in the bulk speed associated with an increase in B near 2013.5 might have been produced by the merging of streams. A “D sheet” (a broad depression in B containing a current sheet moved past V2 from days 320 to 345, 2013. The R- and N-components of the plasma velocity changed across the current sheet. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012PhPl...19g3504K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012PhPl...19g3504K">Influence of heat and particle fluxes nonlocality on spatial distribution of plasma density in two-chamber inductively coupled plasma sources</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Kudryavtsev, A. A.; Serditov, K. Yu. 2012-07-01 This study presents 2D simulations of the two-chamber inductively coupled plasma source where power is supplied in the small discharge chamber and extends by electron thermal conductivity mechanism to the big diffusion chamber. Depending on pressure, two main scenarios of plasma density and its spatial distribution behavior were identified. One case is characterized by the localization of plasma in the small driver chamber where power is deposed. Another case describes when the diffusion chamber becomes the main source of plasma with maximum of the electron density. The differences in spatial distribution are caused by local or non-local behavior of electron energy transport in the discharge volume due to different characteristic scale of heat transfer with electronic conductivity. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010SSEle..54.1430A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010SSEle..54.1430A">Study of current collapse by quiescent-bias-stresses in rf-plasma assisted MBE grown AlGaN/GaN high-electron-mobility transistors</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Arulkumaran, S.; Ng, G. I.; Lee, C. H.; Liu, Z. H.; Radhakrishnan, K.; Dharmarasu, N.; Sun, Z. 2010-11-01 Studies on the influence of quiescent-gate ( Vgs0) and quiescent-drain ( Vds0) bias stresses in rf-plasma MBE grown AlGaN/GaN high-electron-mobility transistors (HEMTs) were performed. The increase of drain current ( ID) collapse by quiescent-bias-stress in AlGaN/GaN HEMTs were observed using pulsed (pulse width = 200 ns; pulse period = 1 ms) IDS- VDS characteristics. The Si 3N 4 passivation suppressed about 80% ID collapse in quiescent-bias-point stressed HEMTs. The remaining 20% ID collapse were not suppressed which may be coming from buffer-related traps. However, more than 10% of ID collapse suppression was observed on un-stressed or fresh-HEMTs. Similarly, improved cut-off frequency ( fT), maximum oscillation frequency ( fmax) and device output power ( Pout) values were also observed on the un-stressed HEMTs. The Si 3N 4 passivation completely suppressed the ID collapse in un-stressed or fresh-HEMTs which leads to 70% improvement in fT and 60% improvement in the device Pout. The Si 3N 4 passivation did not completely suppress ID collapse in the quiescent-bias stressed-HEMTs. This may be due to the generation of additional surface-related traps in the HEMTs by quiescent-bias-stresses. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011ApOpt..50.4226L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011ApOpt..50.4226L">Characteristics of plasma scalds in multilayer dielectric films</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Liu, Xiaofeng; Zhao, Yuan'an; Li, Dawei; Hu, Guohang; Gao, Yanqi; Fan, Zhengxiu; Shao, Jianda 2011-07-01 Plasma scalding is one of the most typical laser damage morphologies induced by a nanosecond laser with a wavelength of 1053nm in HfO2/SiO2 multilayer films. In this paper, the characteristics of plasma scalds are systematically investigated with multiple methods. The scalding behaves as surface discoloration under a microscope. The shape is nearly circular when the laser incidence angle is close to normal incidence and is elliptical at oblique incidence. The nodular-ejection pit is in the center of the scalding region when the laser irradiates at the incidence angle close to normal incidence and in the right of the scalding region when the laser irradiates from left to right at oblique incidence. The maximum damage size of the scalding increases with laser energy. The edge of the scalding is high compared with the unirradiated film surface, and the region tending to the center is concave. Plasma scald is proved to be surface damage. The maximum depth of a scald increases with its size. Tiny pits of nanometer scale can be seen in the scalding film under a scanning electronic microscope at a higher magnification. The absorptions of the surface plasma scalds tend to be approximately the same as the lower absorptions of test sites without laser irradiation. Scalds do not grow during further illumination pulses until 65J/cm2. The formation of surface plasma scalding may be related to the occurrence of the laser-supported detonation wave. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018PlST...20d5103H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018PlST...20d5103H">Design, simulation and construction of the Taban tokamak</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> H, R. MIRZAEI; R, AMROLLAHI 2018-04-01 This paper describes the design and construction of the Taban tokamak, which is located in Amirkabir University of Technology, Tehran, Iran. The Taban tokamak was designed for plasma investigation. The design, simulation and construction of essential parts of the Taban tokamak such as the toroidal field (TF) system, ohmic heating (OH) system and equilibrium field system and their power supplies are presented. For the Taban tokamak, the toroidal magnetic coil was designed to produce a maximum field of 0.7 T at R = 0.45 m. The power supply of the TF was a 130 kJ, 0–10 kV capacitor bank. Ripples of toroidal magnetic field at the plasma edge and plasma center are 0.2% and 0.014%, respectively. For the OH system with 3 kA current, the stray field in the plasma region is less than 40 G over 80% of the plasma volume. The power supply of the OH system consists of two stages, as follows. The fast bank stage is a 120 μF, 0–5 kV capacitor that produces 2.5 kA in 400 μs and the slow bank stage is 93 mF, 600 V that can produce a maximum of 3 kA. The equilibrium system can produce uniform magnetic field at plasma volume. This system’s power supply, like the OH system, consists of two stages, so that the fast bank stage is 500 μF, 800 V and the slow bank stage is 110 mF, 200 V. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25260695','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25260695">Predicting the effect of cytochrome P450 inhibitors on substrate drugs: analysis of physiologically based pharmacokinetic modeling submissions to the US Food and Drug Administration.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Wagner, Christian; Pan, Yuzhuo; Hsu, Vicky; Grillo, Joseph A; Zhang, Lei; Reynolds, Kellie S; Sinha, Vikram; Zhao, Ping 2015-01-01 The US Food and Drug Administration (FDA) has seen a recent increase in the application of physiologically based pharmacokinetic (PBPK) modeling towards assessing the potential of drug-drug interactions (DDI) in clinically relevant scenarios. To continue our assessment of such approaches, we evaluated the predictive performance of PBPK modeling in predicting cytochrome P450 (CYP)-mediated DDI. This evaluation was based on 15 substrate PBPK models submitted by nine sponsors between 2009 and 2013. For these 15 models, a total of 26 DDI studies (cases) with various CYP inhibitors were available. Sponsors developed the PBPK models, reportedly without considering clinical DDI data. Inhibitor models were either developed by sponsors or provided by PBPK software developers and applied with minimal or no modification. The metric for assessing predictive performance of the sponsors' PBPK approach was the R predicted/observed value (R predicted/observed = [predicted mean exposure ratio]/[observed mean exposure ratio], with the exposure ratio defined as [C max (maximum plasma concentration) or AUC (area under the plasma concentration-time curve) in the presence of CYP inhibition]/[C max or AUC in the absence of CYP inhibition]). In 81 % (21/26) and 77 % (20/26) of cases, respectively, the R predicted/observed values for AUC and C max ratios were within a pre-defined threshold of 1.25-fold of the observed data. For all cases, the R predicted/observed values for AUC and C max were within a 2-fold range. These results suggest that, based on the submissions to the FDA to date, there is a high degree of concordance between PBPK-predicted and observed effects of CYP inhibition, especially CYP3A-based, on the exposure of drug substrates. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018BSRSL..87..193A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018BSRSL..87..193A">X-ray observations of the colliding wind binary WR 25</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Arora, Bharti; Pandey, Jeewan Chandra 2018-04-01 Using the archival data obtained from Chandra and Suzaku spanning over '8 years, we present an analysis of a WN6h+O4f Wolf-Rayet binary, WR 25. The X-ray light curves folded over a period of '208 d in the 0.3 - 10.0 keV energy band showed phase-locked variability where the count rates were found to be maximum near the periastron passage. The X-ray spectra of WR 25 were well explained by a two-temperature plasma model with temperatures of 0.64 ± 0.01 and 2.96 ± 0.05 keV and are consistent with previous results. The orbital phase dependent local hydrogen column density was found to be maximum just after the periastron passage, when the WN type star is in front of the O star. The hard (2.0 - 10.0 keV) X-ray luminosity was linearly dependent on the inverse of binary separation which confirms that WR 25 is a colliding wind binary. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19658871','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19658871">Tokamak startup using point-source dc helicity injection.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Battaglia, D J; Bongard, M W; Fonck, R J; Redd, A J; Sontag, A C 2009-06-05 Startup of a 0.1 MA tokamak plasma is demonstrated on the ultralow aspect ratio Pegasus Toroidal Experiment using three localized, high-current density sources mounted near the outboard midplane. The injected open field current relaxes via helicity-conserving magnetic turbulence into a tokamaklike magnetic topology where the maximum sustained plasma current is determined by helicity balance and the requirements for magnetic relaxation. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26663305','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26663305">The pharmacokinetics of intraosseous atropine in hypovolemic swine.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Yost, Jonathan; Baldwin, Phillip; Bellenger, Sarah; Bradshaw, Freida; Causapin, Edna; Demotica, Richelle; Livingston, Michael; Lee, Cynthia; Gegel, Brian; Burgert, James; Claessens, Adam; Johnson, Don; Loughren, Michael 2015-01-01 Compare the pharmacokinetics of atropine administered via the intravenous (IV), intramuscular (IM), and intraosseous (IO) routes in a normovolemic and hypovolemic swine model. Prospective, between subjects, experimental study. Vivarium. Yorkshire-cross swine (N = 36). Atropine was administered via IV, IM, or IO routes to normovolemic and hypovolemic swine. Blood samples were drawn at regular intervals after atropine administration and analyzed for plasma atropine concentration. Pharmacokinetic parameters were obtained from modeling the plasma concentrations. Pharmacokinetic parameters, maximum concentration (Cmax) and time to maximum concentration (Tmax). The IV and IO groups in both the normovolemic and hypovolemic models reached peak plasma concentration immediately and had a very rapid distribution phase with no apparent absorption phase for the IO groups. Peak plasma concentration and time to reach peak concentration were both significantly lower for the IM groups. There was a significant increase in absorption time with IM administration in the hypovolemic model compared to the normovolemic model. The IO route is an effective method of administering atropine and is comparable to the IV route even under conditions of significant hemorrhage. Therapeutic levels of atropine may be delayed and possibly difficult to obtain via IM injection in the presence of hypovolemic shock. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2002EGSGA..27.4110Z','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2002EGSGA..27.4110Z">Frictional Heating of Ions In The F2-region of The Ionosphere</a> <a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a> Zhizhko, G. O.; Vlasov, V. G. Auroral electron beams unstable on the Cherenkov resonance are stabilized by large- scale inhomogeneity of the plasma density during all their way from the acceleration region to the E-region of the ionosphere. The generation of plasma waves by beam is possible only in the region of small plasma density gradients, that always is the area of the F2-region maximum. Thus, collective dissipation of the electron beam energy occurs in the local region with the length about several tens of kilometers. This leads to the intensive heating of the electrons(up to temperatures about 10000 K) and will give origin to the ion upflows with velocity about 1 km/s and density about 109 cm-2 s-1. These flows can result in the ion frictional heating. At the same time ion temperatures reach the values about 5000 K. A numerical simulation of the ion frictional heating in the presence of collective elec- tron heating in the high-latitude F2-region of the ionosphere was performed. The sim- ulation has shown that the most critical parameter for the occurence of the ion fric- tional heating was the the steepness of the plasma density profile above the F2-region maximum. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26352959','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26352959">PHARMACOKINETIC PROPERTIES OF A SINGLE ADMINISTRATION OF ORAL GABAPENTIN IN THE GREAT HORNED OWL (BUBO VIRGINIANUS).</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Yaw, Taylor J; Zaffarano, Bianca A; Gall, Andrew; Olds, June E; Wulf, Larry; Papastavros, Efthimia; Coetzee, Johann F 2015-09-01 Gabapentin (1-[aminomethyl] cyclohexane acetic acid) is a γ-aminobutyric acid analogue that has been shown to be efficacious for neuropathic pain control in humans. Plasma gabapentin concentrations >2 μg/ml are considered effective in treating epilepsy in humans and are suggested to provide analgesia for neuropathic pain. This study investigated the pharmacokinetics of a single oral dose of gabapentin suspension (11 mg/kg) in great horned owls ( Bubo virginianus ). Plasma gabapentin concentrations were determined in six healthy birds for 48 hr using high-performance liquid chromatography with mass spectrometric detection. Plasma gabapentin concentrations were estimated by noncompartmental pharmacokinetic analysis. The harmonic mean (±SD) maximum concentration (Cmax), time to maximum concentration (Tmax), and elimination half-life (tv2λZ) for gabapentin (11 mg/kg) were 6.17±0.83 μg/ml, 51.43±5.66 min, and 264.60±69.35 min, respectively. In this study, plasma gabapentin concentrations were maintained above 2 μg/ml for 528 min (8.8 hr), suggesting that gabapentin administered orally every 8 hr may be appropriate in great horned owls. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2014890','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2014890">Effect of cimetidine and ranitidine on pharmacokinetics and pharmacodynamics of a single dose of dofetilide</a> <a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a> Abel, Samantha; Nichols, Donald J; Brearley, Christopher J; Eve, Malcolm D 2000-01-01 Aims The aim of this open-label, placebo-controlled, randomized, four-period crossover study was to determine the effects of cimetidine and ranitidine on the pharmacokinetics and pharmacodynamics of a single dose of dofetilide. Methods Twenty healthy male subjects received 100 or 400 mg twice daily of cimetidine, 150 mg twice daily of ranitidine, or placebo for 4 days. On the second day, a single oral 500 μg dose of dofetilide was administered immediately after the morning doses of cimetidine, ranitidine, or placebo. Treatment periods were separated by 1–2 weeks. Pharmacokinetic parameters were determined from plasma and urinary dofetilide concentrations; prolongation of the QTc interval was determined from three-lead electrocardiograms. Results Ranitidine did not significantly affect the pharmacokinetics or pharmacodynamics of dofetilide; however, a dose-dependent increase in exposure to dofetilide was observed with cimetidine. When dofetilide was administered with 100 and 400 mg of cimetidine, the area under the plasma concentration-time curve of dofetilide increased by 11% and 48% and the maximum plasma dofetilide concentration increased by 11% and 29%, respectively. The respective cimetidine doses reduced renal clearance of dofetilide by 13% and 33% and nonrenal clearance by 5% and 21%. Dofetilide-induced prolongation of the QTc interval was enhanced by cimetidine; the mean maximum change in QTc interval from baseline was increased by 22% and 33% with 100 and 400 mg of cimetidine, respectively. However, the relationship between the prolongation of the QTc interval and plasma dofetilide concentrations was unaffected by cimetidine or ranitidine; a 1 ng ml−1 increase in plasma dofetilide concentration produced a 17–19 ms prolongation of the QTc interval. Dofetilide was well tolerated, with no treatment-related adverse events or laboratory abnormalities. Conclusions These results suggest that cimetidine increased dofetilide exposure by inhibiting renal tubular dofetilide secretion, whereas ranitidine did not. This effect is not an H2-receptor antagonist class effect but is specific to cimetidine. If therapy with an H2-receptor antagonist is required, it is recommended that cimetidine at all doses be avoided; since ranitidine has no effect on dofetilide pharmacokinetics or prolongation of the QTc interval, it can be seen as a suitable alternative. PMID:10606839 </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/7039821','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/7039821">Pharmacology of 13-cis-retinoic acid in humans.</a> <a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a> Kerr, I G; Lippman, M E; Jenkins, J; Myers, C E 1982-05-01 Vitamin A and its analogs (retinoids) have shown great promise for the chemoprevention of cancer as well as being a possible new class of chemotherapeutic agents. A Phase I and II trial of 13-cis-retinoic acid in advanced cancers was initiated, and the clinical pharmacology of the drug was studied. All patients received p.o. 13-cis-retinoic acid starting at 0.5 mg/kg/day, escalating over 4 weeks to a maximum dose of 8 mg/kg/day in divided doses. Although there was a linear correlation of plasma concentration with dose escalation, large inter-individual variations in peak plasma concentrations were noted. At the maximum drug dose, the mean peak plasma concentration was 4 X 10(-6) M. There was little drug accumulation on this schedule, as trough concentrations between p.o. doses often dropped below 1 X 10(-6) M. The drug was metabolized extensively to a metabolite, the concentrations of which exceeding parent 13-cis-retinoic acid concentrations with chronic dosing. Retinol concentrations were below the normal range. </li> <li> <a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22407932-envelope-matching-enhanced-backward-raman-amplification-using-self-ionizing-plasmas','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22407932-envelope-matching-enhanced-backward-raman-amplification-using-self-ionizing-plasmas">Envelope matching for enhanced backward Raman amplification by using self-ionizing plasmas</a> <a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a> Zhang, Z. M.; Zhang, B.; Hong, W. 2014-12-15 Backward Raman amplification (BRA) in plasmas has been promoted as a means for generating ultrapowerful laser pulses. For the purpose of achieving the maximum intensities over the shortest distances, an envelope matching between the seed pulse and the amplification gain is required, i.e., the seed pulse propagates at the same velocity with the gain such that the peak of the seed pulse can always enjoy the maximum gain. However, such an envelope matching is absent in traditional BRA because in the latter the amplification gain propagates at superluminous velocity while the seed pulse propagates at the group velocity, which ismore » less than the speed of light. It is shown here that, by using self-ionizing plasmas, the speed of the amplification gain can be well reduced to reach the envelope matching regime. 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Sample records for maximum observed plasma