Sample records for measured be2 values

  1. On the equivalence of experimental B(E2) values determined by various techniques

    DOE PAGES

    Birch, M.; Pritychenko, B.; Singh, B.

    2016-06-30

    In this paper, we establish the equivalence of the various techniques for measuring B(E2) values using a statistical analysis. Data used in this work come from the recent compilation by B. Pritychenko et al. (2016). We consider only those nuclei for which the B(E2) values were measured by at least two different methods, with each method being independently performed at least twice. Our results indicate that most prevalent methods of measuring B(E2) values are equivalent, with some weak evidence that Doppler-shift attenuation method (DSAM) measurements may differ from Coulomb excitation (CE) and nuclear resonance fluorescence (NRF) measurements. However, such anmore » evidence appears to arise from discrepant DSAM measurements of the lifetimes for 60Ni and some Sn nuclei rather than a systematic deviation in the method itself.« less

  2. Revisiting Grodzins systematics of B(E2) values

    DOE PAGES

    Pritychenko, B.; Birch, M.; Singh, B.

    2017-04-03

    Using Grodzins formalism, we analyze systematics of our latest evaluated B(E2) data for all the even–even nuclei in Z=2–104. The analysis indicates a low predictive power of systematics for a large number of cases, and a strong correlation between B(E2) fit values and nuclear structure effects. These findings provide a strong rationale for introduction of individual or elemental (grouped by Z) fit parameters. The current estimates of quadrupole collectivities for systematics of even–even nuclei yield complementary values for comparison with experimental results and theoretical calculations. Furthermore, the lists of fit parameters and predicted B(E2) values are given and possible implicationsmore » are discussed.« less

  3. Measuring the B(E2) of the 1/2- ->3/2- transition in 7 Be

    NASA Astrophysics Data System (ADS)

    Henderson, S. L.; Ahn, T.; Caprio, M. A.; Constantinou, Ch.; Simon, A.; Twinsol Collaboration

    2017-09-01

    Ab-initio methods have been successful in describing the structure of light nuclei using realistic nucleon-nucleon interactions, but more experimental data is needed for light unstable nuclei. Recent no-core configuration interaction calculations have made predictions for the ratio of E2 transition strengths for the first excited state transition in 7 Be and 7 Li . Additional calculations that include clustering effects show a significant difference in the 7 Be and 7 Li B(E2) value. The E2 transition strength of the 7 Be first excited state has never been measured, which provides an interesting opportunity to investigate the accuracy of these calculations. To measure this E2 transition strength, a Coulomb Excitation experiment was performed at the University of Notre Dame. 7 Be was produced and separated using TwinSol. A beam of 7 Be ions were scattered off a gold target and the gamma rays from the inelastically scattered ions were detected using six clover Ge detectors. The most recent results for the E2 transition strength and its comparison to the no-core configuration interaction approach will be shown. In addition, new systematic checks on the experiment will be presented including the first stages of a Geant4 simulation to help account for beam anisotropies. This work has been supported by US NSF Grant No. PHY 14-19765 and DOE Grant Number DE-FG02-95ER-40934.

  4. Can the reinforcing value of food be measured in bulimia nervosa?

    PubMed Central

    Schebendach, Janet; Broft, Allegra; Foltin, Richard W.; Walsh, B. Timothy

    2013-01-01

    Binge eating is a core clinical feature of bulimia nervosa (BN). Enhanced reinforcing value of food may play a role in this behavioral disturbance, but a systematic behavioral assessment of objective measures of the rewarding value of binge eating is lacking. The purpose of this study was to quantify the reinforcing value of food in BN patients as compared with normal controls. A progressive ratio (PR) computerized work task was completed under binge and non-binge instruction. The task consisted of 12 trials. The first trial required 50 keyboard taps to earn one portion of yogurt shake, and subsequent trials required progressive work increments of 200 taps for each additional portion. Completion of all 12 trials required 13,800 taps to earn 2,100 ml of shake. The breakpoint, defined as the largest ratio completed before a participant stopped working, was the measure of reinforcing efficacy. Ten patients and 10 controls completed the experiment. Under binge instruction, patients completed more trials and taps, and had a higher breakpoint than controls. The non-binge instruction yielded opposite findings; compared to controls, patients completed fewer trials and taps, and had a lower breakpoint. These results support the feasibility and potential utility of a PR task to quantify the reinforcing value of food in patients with BN. PMID:23178173

  5. New measurement of the lifetime of the 2 + 1 state of 12Be

    DOE PAGES

    Morse, C.; McCutchan, E. A.; Iwasaki, H.; ...

    2017-05-03

    The lifetime of themore » $$2_1^+$$ state at 2.1 MeV in $$^{12}$$Be has been measured using inelastic scattering of a $$^{12}$$Be beam at 43 MeV/nucleon with a gold target. Through the Doppler shift attenuation method, the mean-life of the $$2_1^+$$ state has been determined as 2.5±0.7(stat)±0.3 (syst) ps, which gives a B(E2; $$2_1^+$$ → $$0_{g.s.}^+$$)) value of 4.9±1.3±0.5 in Weisskopf units. The result shows a large quadrupole strength in the ground state transition, providing further evidence on the disappearance of the N=8 magic number. The B(E2; $$2_1^+$$ → $$0_{g.s.}^+$$) value together with the deformation length measured by proton inelastic scattering yields a neutron quadrupole matrix element two times larger than those for $$^{14}$$C and $${16}$$O.« less

  6. Measuring Children's Environmental Attitudes and Values in Northwest Mexico: Validating a Modified Version of Measures to Test the Model of Ecological Values (2-MEV)

    ERIC Educational Resources Information Center

    Schneller, A. J.; Johnson, B.; Bogner, F. X.

    2015-01-01

    This paper describes the validation process of measuring children's attitudes and values toward the environment within a Mexican sample. We applied the Model of Ecological Values (2-MEV), which has been shown to be valid and reliable in 20 countries, including one Spanish speaking culture. Items were initially modified to fit the regional dialect,…

  7. A revised B(E2;2+ 1 → 0+ 1) value in the semi-magic nucleus 210Po

    NASA Astrophysics Data System (ADS)

    Kocheva, D.; Rainovski, G.; Jolie, J.; Pietralla, N.; Blazhev, A.; Astier, A.; Altenkirch, R.; Ansari, S.; Braunroth, Th.; Cortés, M. L.; Dewald, A.; Diel, F.; Djongolov, M.; Fransen, C.; Gladnishki, K.; Hennig, A.; Karayonchev, V.; Keatings, J. M.; Kluge, E.; Litzinger, J.; Müller-Gatermann, C.; Petkov, P.; Rudigier, M.; Scheck, M.; Scholz, Ph.; Spagnoletti, P.; Spieker, M.; Stahl, C.; Stegmann, R.; Stoyanova, M.; Thöle, P.; Warr, N.; Werner, V.; Witt, W.; Wölk, D.; Zell, K. O.; Van Isacker, P.; Ponomarev, V. Yu.

    2017-09-01

    The lifetimes of the 2^+_1 , the 2^+_2 and the 3^-_1 states of 210Po have been measured in the 208Pb(12C,10Be)210Po transfer reaction by the Doppler-shift attenuation method. The result for the lifetime of the 2^+_1 state is about three times shorter than the adopted value. However, the new value still does not allow for a consistent description of the properties of the yrast 2^+_1 , 4^+_1 , 6^+_1 , and 8^+_1 states of 210Po in the framework of nuclear shell models. Quasi-particle Phonon Model (QPM) calculations also cannot overcome this problem thus indicating the existence of a peculiarity which is neglected in both theoretical approaches.

  8. Can the reinforcing value of food be measured in bulimia nervosa?

    PubMed

    Schebendach, Janet; Broft, Allegra; Foltin, Richard W; Walsh, B Timothy

    2013-03-01

    Binge eating is a core clinical feature of bulimia nervosa (BN). Enhanced reinforcing value of food may play a role in this behavioral disturbance, but a systematic behavioral assessment of objective measures of the rewarding value of binge eating is lacking. The purpose of this study was to quantify the reinforcing value of food in BN patients as compared with normal controls. A progressive ratio (PR) computerized work task was completed under binge and non-binge instruction. The task consisted of 12 trials. The first trial required 50 keyboard taps to earn one portion of yogurt shake, and subsequent trials required progressive work increments of 200 taps for each additional portion. Completion of all 12 trials required 13,800 taps to earn 2100ml of shake. The breakpoint, defined as the largest ratio completed before a participant stopped working, was the measure of reinforcing efficacy. Ten patients and 10 controls completed the experiment. Under binge instruction, patients completed more trials and taps, and had a higher breakpoint than controls. The non-binge instruction yielded opposite findings; compared to controls, patients completed fewer trials and taps, and had a lower breakpoint. These results support the feasibility and potential utility of a PR task to quantify the reinforcing value of food in patients with BN. Copyright © 2012 Elsevier Ltd. All rights reserved.

  9. Redox potential - field measurements - meassured vs. expected values

    NASA Astrophysics Data System (ADS)

    Stavělová, Monika; Kovář, Martin

    2016-04-01

    data must be approached keeping in mind that their accuracy does not correspond with theoretical calculations and their values must be assessed in combination with other parameters - e.g. in case of interpretations of measured redox during remediation of contaminated sites it is appropriate to assess these values together with determined concentrations of significant terminal electron acceptors (TEA) whose laboratory determination is more accurate (NO3-, NO2-, Fe2+,Mn2+ , SO42-, H2S+S2-,CH4….). Acknowledgement: This study has been funded by the Technology Agency of the Czech Republic within the research project Nanobiowat (No. TE01010218), and by AECOM CZ, s.r.o.

  10. Precision measurement of the electromagnetic dipole strengths in Be11

    NASA Astrophysics Data System (ADS)

    Kwan, E.; Wu, C. Y.; Summers, N. C.; Hackman, G.; Drake, T. E.; Andreoiu, C.; Ashley, R.; Ball, G. C.; Bender, P. C.; Boston, A. J.; Boston, H. C.; Chester, A.; Close, A.; Cline, D.; Cross, D. S.; Dunlop, R.; Finlay, A.; Garnsworthy, A. B.; Hayes, A. B.; Laffoley, A. T.; Nano, T.; Navrátil, P.; Pearson, C. J.; Pore, J.; Quaglioni, S.; Svensson, C. E.; Starosta, K.; Thompson, I. J.; Voss, P.; Williams, S. J.; Wang, Z. M.

    2014-05-01

    The electromagnetic dipole strength in Be11 between the bound states has been measured using low-energy projectile Coulomb excitation at bombarding energies of 1.73 and 2.09 MeV/nucleon on a Pt196 target. An electric dipole transition probability B(E1;1/2-→1/2+)=0.102(2) e2fm was determined using the semi-classical code Gosia, and a value of 0.098(4) e2fm was determined using the Extended Continuum Discretized Coupled Channels method with the quantum mechanical code FRESCO. These extracted B(E1) values are consistent with the average value determined by a model-dependent analysis of intermediate energy Coulomb excitation measurements and are approximately 14% lower than that determined by a lifetime measurement. The much-improved precisions of 2% and 4% in the measured B(E1) values between the bound states deduced using Gosia and the Extended Continuum Discretized Coupled Channels method, respectively, compared to the previous accuracy of ˜10% will help in our understanding of and better improve the realistic inter-nucleon interactions.

  11. One Moon, many measurements 1: Radiance values

    NASA Astrophysics Data System (ADS)

    Pieters, C. M.; Boardman, J. W.; Ohtake, M.; Matsunaga, T.; Haruyama, J.; Green, R. O.; Mall, U.; Staid, M. I.; Isaacson, P. J.; Yokota, Y.; Yamamoto, S.; Besse, S.; Sunshine, J. M.

    2013-09-01

    Several modern optical instruments orbited the Moon during 2008 and 2009 onboard the SELENE and Chandrayaan-1 spacecraft and provided a welcomed feast of spectroscopic data to be used for scientific analyses. The different spatial and spectral resolutions of these sensors along with diverse illumination geometry during data acquisition make each set of data unique, and each instrument contributes special value to integrated science analyses. In order to provide the maximum science benefit, we have undertaken a careful cross-validation of radiance data among these orbital instruments and also a set of systematic data acquired using Earth-based telescopes. Most radiance values at 750 nm fall between 0 and 100 W/(m2 μm sr), but a small important fraction can be up to ×2 to ×3 that value, with the largest values occurring at the highest spatial resolution. All instruments are in agreement about overall spectral properties of lunar materials, but small systematic differences are documented between instruments. Lunar radiance values measured with remote sensors for landing sites are all not as high as that estimated from laboratory measurements of returned soil. This is largely because laboratory measurements of lunar soils cannot retain or duplicate the fine structure of lunar regolith found in the natural space environment.

  12. /B(E2) values from low-energy Coulomb excitation at an ISOL facility: the /N=80,82 Te isotopes

    NASA Astrophysics Data System (ADS)

    Barton, C. J.; Caprio, M. A.; Shapira, D.; Zamfir, N. V.; Brenner, D. S.; Gill, R. L.; Lewis, T. A.; Cooper, J. R.; Casten, R. F.; Beausang, C. W.; Krücken, R.; Novak, J. R.

    2003-01-01

    B(E2;0+1→2+1) values for the unstable, neutron-rich nuclei 132,134Te were determined through Coulomb excitation, in inverse kinematics, of accelerated beams of these nuclei. The systematics of measured B(E2) values from the ground state to the first excited state have been extended to the N=82 shell closure in the Te nuclei and have been compared with the predictions of different theories. The measurements were performed at the Holifield Radioactive Ion Beam Facility (HRIBF) using the GRAFIK detector. The success of this approach, which couples a 5.7% efficient through-well NaI(Tl) γ-ray detector with thin foil microchannel plate beam detectors, also demonstrates the feasibility for Coulomb excitation studies of neutron-rich nuclei even further from the valley of beta stability, both at present-generation ISOL facilities and at the proposed Rare Isotope Accelerator.

  13. Measuring Values in Environmental Research: A Test of an Environmental Portrait Value Questionnaire

    PubMed Central

    Bouman, Thijs; Steg, Linda; Kiers, Henk A. L.

    2018-01-01

    Four human values are considered to underlie individuals’ environmental beliefs and behaviors: biospheric (i.e., concern for environment), altruistic (i.e., concern for others), egoistic (i.e., concern for personal resources) and hedonic values (i.e., concern for pleasure and comfort). These values are typically measured with an adapted and shortened version of the Schwartz Value Survey (SVS), to which we refer as the Environmental-SVS (E-SVS). Despite being well-validated, recent research has indicated some concerns about the SVS methodology (e.g., comprehensibility, self-presentation biases) and suggested an alternative method of measuring human values: The Portrait Value Questionnaire (PVQ). However, the PVQ has not yet been adapted and applied to measure values most relevant to understand environmental beliefs and behaviors. Therefore, we tested the Environmental-PVQ (E-PVQ) – a PVQ variant of E-SVS –and compared it with the E-SVS in two studies. Our findings provide strong support for the validity and reliability of both the E-SVS and E-PVQ. In addition, we find that respondents slightly preferred the E-PVQ over the E-SVS (Study 1). In general, both scales correlate similarly to environmental self-identity (Study 1), energy behaviors (Studies 1 and 2), pro-environmental personal norms, climate change beliefs and policy support (Study 2). Accordingly, both methodologies show highly similar results and seem well-suited for measuring human values underlying environmental behaviors and beliefs. PMID:29743874

  14. B(E2)↑ Measurements for Radioactive Neutron-Rich Ge Isotopes: Reaching the N=50 Closed Shell

    NASA Astrophysics Data System (ADS)

    Padilla-Rodal, E.; Galindo-Uribarri, A.; Baktash, C.; Batchelder, J. C.; Beene, J. R.; Bijker, R.; Brown, B. A.; Castaños, O.; Fuentes, B.; del Campo, J. Gomez; Hausladen, P. A.; Larochelle, Y.; Lisetskiy, A. F.; Mueller, P. E.; Radford, D. C.; Stracener, D. W.; Urrego, J. P.; Varner, R. L.; Yu, C.-H.

    2005-03-01

    The B(E2;0+1→2+1) values for the radioactive neutron-rich germanium isotopes 78,80Ge and the closed neutron shell nucleus 82Ge were measured at the HRIBF using Coulomb excitation in inverse kinematics. These data allow a study of the systematic trend between the subshell closures at N=40 and 50. The B(E2) behavior approaching N=50 is similar to the trend observed for heavier isotopic chains. A comparison of the experimental results with a shell model calculation demonstrates persistence of the N=50 shell gap and a strong sensitivity of the B(E2) values to the effective interaction.

  15. How Can Value-Added Measures Be Used for Teacher Improvement? What We Know Series: Value-Added Methods and Applications. Knowledge Brief 13

    ERIC Educational Resources Information Center

    Loeb, Susanna

    2013-01-01

    The question for this brief is whether education leaders can use value-added measures as tools for improving schooling and, if so, how to do this. Districts, states, and schools can, at least in theory, generate gains in educational outcomes for students using value-added measures in three ways: creating information on effective programs, making…

  16. 19 CFR 152.107 - Value if other values cannot be determined or used.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Value if other values cannot be determined or used... of Merchandise § 152.107 Value if other values cannot be determined or used. (a) Reasonable adjustments. If the value of imported merchandise cannot be determined or otherwise used for the purposes of...

  17. The roles of values, behavior, and value-behavior fit in the relation of agency and communion to well-being.

    PubMed

    Buchanan, Kathryn; Bardi, Anat

    2015-06-01

    Four studies examined whether agency and communion values, behaviors, or an interaction between values and behaviors (value-behavior fit) would predict well-being. In addition, Study 2 examined whether agency and communion goals, behaviors, or goal-behavior fit would predict well-being. In all four studies, participants completed online questionnaires containing measures of agency and communion values, behaviors, and well-being. In Studies 1 and 4, participants were recruited from the general population (respectively, N = 371, Mage  = 37.49, and N = 133, Mage  = 36.59). In Studies 2 and 3, participants were undergraduate students (respectively, N = 239, Mage  = 20.8, and N = 242, Mage  = 21.6). All four studies consistently found that agency and communion behaviors were significantly positively correlated with both subjective and psychological well-being. There was no strong indication that either values were directly associated with well-being. Neither was there any indication that well-being was predicted by value-behavior fit. The implications of these findings for theory and improving well-being are discussed. © 2014 Wiley Periodicals, Inc.

  18. English Value-Added Measures: Examining the Limitations of School Performance Measurement

    ERIC Educational Resources Information Center

    Perry, Thomas

    2016-01-01

    Value-added "Progress" measures are to be introduced for all English schools in 2016 as "headline" measures of school performance. This move comes despite research highlighting high levels of instability in value-added measures and concerns about the omission of contextual variables in the planned measure. This article studies…

  19. Heisenberg's uncertainty principle for simultaneous measurement of positive-operator-valued measures

    NASA Astrophysics Data System (ADS)

    Miyadera, Takayuki; Imai, Hideki

    2008-11-01

    A limitation on simultaneous measurement of two arbitrary positive-operator-valued measures is discussed. In general, simultaneous measurement of two noncommutative observables is only approximately possible. Following Werner’s formulation, we introduce a distance between observables to quantify an accuracy of measurement. We derive an inequality that relates the achievable accuracy with noncommutativity between two observables. As a byproduct a necessary condition for two positive-operator-valued measures to be simultaneously measurable is obtained.

  20. [The prognostic value of cerebral oxygen saturation measurement for assessing prognosis after cardiopulmonary resuscitation].

    PubMed

    Inal, Mehmet Turan; Memiş, Dilek; Yıldırım, Ilker; Uğur, Hüseyin; Erkaymaz, Aysegul; Turan, F Nesrin

    Despite new improvements on cardiopulmonary resuscitation (CPR), brain damage is very often after resuscitation. To assess the prognostic value of cerebral oxygen saturation measurement (rSO 2 ) for assessing prognosis on patients after cardiopulmonary resuscitation. Retrospective analysis. We analyzed 25 post-CPR patients (12 female and 13 male). All the patients were cooled to a target temperature of 33-34°C. The Glascow Coma Scale (GCS), Corneal Reflexes (CR), Pupillary Reflexes (PR), arterial Base Excess (BE) and rSO 2 measurements were taken on admission. The rewarming GCS, CR, PR, BE and rSO 2 measurements were made after the patient's temperature reached 36°C. In survivors, the baseline rSO 2 value was 67.5 (46-70) and the percent difference between baseline and rewarming rSO 2 value was 0.03 (0.014-0.435). In non-survivors, the baseline rSO 2 value was 30 (25-65) and the percent difference between baseline and rewarming rSO 2 value was 0.031 (-0.08 to -20). No statistical difference was detected on percent changes between baseline and rewarming values of rSO 2. Statistically significant difference was detected between baseline and rewarming GCS groups (p=0.004). No statistical difference was detected between GCS, CR, PR, BE and rSO 2 to determine the prognosis. Despite higher values of rSO 2 on survivors than non-survivors, we found no statistically considerable difference between groups on baseline and the rewarming rSO 2 values. Since the measurement is simple, and not affected by hypotension and hypothermia, the rSO 2 may be a useful predictor for determining the prognosis after CPR. Copyright © 2016 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved.

  1. Can Value-Added Measures of Teacher Performance Be Trusted?

    ERIC Educational Resources Information Center

    Guarino, Cassandra M.; Reckase, Mark D.; Wooldridge, Jeffrey M.

    2015-01-01

    We investigate whether commonly used value-added estimation strategies produce accurate estimates of teacher effects under a variety of scenarios. We estimate teacher effects in simulated student achievement data sets that mimic plausible types of student grouping and teacher assignment scenarios. We find that no one method accurately captures…

  2. Measuring value sensitivity in medicine.

    PubMed

    Ineichen, Christian; Christen, Markus; Tanner, Carmen

    2017-01-28

    Value sensitivity - the ability to recognize value-related issues when they arise in practice - is an indispensable competence for medical practitioners to enter decision-making processes related to ethical questions. However, the psychological competence of value sensitivity is seldom an explicit subject in the training of medical professionals. In this contribution, we outline the traditional concept of moral sensitivity in medicine and its revised form conceptualized as value sensitivity and we propose an instrument that measures value sensitivity. We developed an instrument for assessing the sensitivity for three value groups (moral-related values, values related to the principles of biomedical ethics, strategy-related values) in a four step procedure: 1) value identification (n = 317); 2) value representation (n = 317); 3) vignette construction and quality evaluation (n = 37); and 4) instrument validation by comparing nursing professionals with hospital managers (n = 48). We find that nursing professionals recognize and ascribe importance to principle-related issues more than professionals from hospital management. The latter are more likely to recognize and ascribe importance to strategy-related issues. These hypothesis-driven results demonstrate the discriminatory power of our newly developed instrument, which makes it useful not only for health care professionals in practice but for students and people working in the clinical context as well.

  3. Measurement Theory Based on the Truth Values Violates Local Realism

    NASA Astrophysics Data System (ADS)

    Nagata, Koji

    2017-02-01

    We investigate the violation factor of the Bell-Mermin inequality. Until now, we use an assumption that the results of measurement are ±1. In this case, the maximum violation factor is 2( n-1)/2. The quantum predictions by n-partite Greenberger-Horne-Zeilinger (GHZ) state violate the Bell-Mermin inequality by an amount that grows exponentially with n. Recently, a new measurement theory based on the truth values is proposed (Nagata and Nakamura, Int. J. Theor. Phys. 55:3616, 2016). The values of measurement outcome are either +1 or 0. Here we use the new measurement theory. We consider multipartite GHZ state. It turns out that the Bell-Mermin inequality is violated by the amount of 2( n-1)/2. The measurement theory based on the truth values provides the maximum violation of the Bell-Mermin inequality.

  4. High-precision Penning trap mass measurements of 9,10Be and the one-neutron halo nuclide 11Be

    NASA Astrophysics Data System (ADS)

    Ringle, R.; Brodeur, M.; Brunner, T.; Ettenauer, S.; Smith, M.; Lapierre, A.; Ryjkov, V. L.; Delheij, P.; Drake, G. W. F.; Lassen, J.; Lunney, D.; Dilling, J.

    2009-05-01

    Penning trap mass measurements of 9Be, 10Be (t1 / 2 = 1.51 My), and the one-neutron halo nuclide 11Be (t1 / 2 = 13.8 s) have been performed using TITAN at TRIUMF. The resulting 11Be mass excess (ME = 20 177.60 (58) keV) is in agreement with the current Atomic Mass Evaluation (AME03) [G. Audi, et al., Nucl. Phys. A 729 (2003) 337] value, but is over an order of magnitude more precise. The precision of the mass values of 9,10Be have been improved by about a factor of four and reveal a ≈ 2 σ deviation from the AME mass values. Results of new atomic physics calculations are presented for the isotope shift of 11Be relative to 9Be, and it is shown that the new mass values essentially remove atomic mass uncertainties as a contributing factor in determining the relative nuclear charge radius from the isotope shift. The new mass values of 10,11Be also allow for a more precise determination of the single-neutron binding energy of the halo neutron in 11Be.

  5. Precise Penning trap measurements of double β-decay Q-values

    NASA Astrophysics Data System (ADS)

    Redshaw, M.; Brodeur, M.; Bollen, G.; Bustabad, S.; Eibach, M.; Gulyuz, K.; Izzo, C.; Lincoln, D. L.; Novario, S. J.; Ringle, R.; Sandler, R.; Schwarz, S.; Valverde, A. A.

    2015-10-01

    The double β-decay (ββ -decay) Q-value, defined as the mass difference between parent and daughter atoms, is an important parameter for both two-neutrino ββ -decay (2 νββ) and neutrinoless ββ -decay (0 νββ) experiments. The Q-value enters into the calculation of the phase space factors, which relate the measured ββ -decay half-life to the nuclear matrix element and, in the case of 0 νββ , the effective Majorana mass of the neutrino. In addition, the Q-value defines the total kinetic energy of the two electrons emitted in 0 νββ , corresponding to the location of the single peak that is the sought after signature of 0 νββ . Hence, it is essential to have a precise and accurate Q-value determination. Over the last decade, the Penning trap mass spectrometry community has made a significant effort to provide precise ββ -decay Q-value determinations. Here we report on recent measurements with the Low Energy Beam and Ion Trap (LEBIT) facility at the National Superconducting Cyclotron Laboratory (NSCL) of the 48Ca, 82Se, and 96Zr Q-values. These measurements complete the determination of ββ -decay Q-values for the 11 ``best'' candidates (those with Q >2 MeV). We also report on a measurement of the 78Kr double electron capture (2EC) Q-value and discuss ongoing Penning trap measurements relating to ββ -decay and 2EC. Support from NSF Contract No. PHY-1102511, and DOE Grant No. 03ER-41268.

  6. Measuring Incompatible Observables by Exploiting Sequential Weak Values.

    PubMed

    Piacentini, F; Avella, A; Levi, M P; Gramegna, M; Brida, G; Degiovanni, I P; Cohen, E; Lussana, R; Villa, F; Tosi, A; Zappa, F; Genovese, M

    2016-10-21

    One of the most intriguing aspects of quantum mechanics is the impossibility of measuring at the same time observables corresponding to noncommuting operators, because of quantum uncertainty. This impossibility can be partially relaxed when considering joint or sequential weak value evaluation. Indeed, weak value measurements have been a real breakthrough in the quantum measurement framework that is of the utmost interest from both a fundamental and an applicative point of view. In this Letter, we show how we realized for the first time a sequential weak value evaluation of two incompatible observables using a genuine single-photon experiment. These (sometimes anomalous) sequential weak values revealed the single-operator weak values, as well as the local correlation between them.

  7. Measuring Incompatible Observables by Exploiting Sequential Weak Values

    NASA Astrophysics Data System (ADS)

    Piacentini, F.; Avella, A.; Levi, M. P.; Gramegna, M.; Brida, G.; Degiovanni, I. P.; Cohen, E.; Lussana, R.; Villa, F.; Tosi, A.; Zappa, F.; Genovese, M.

    2016-10-01

    One of the most intriguing aspects of quantum mechanics is the impossibility of measuring at the same time observables corresponding to noncommuting operators, because of quantum uncertainty. This impossibility can be partially relaxed when considering joint or sequential weak value evaluation. Indeed, weak value measurements have been a real breakthrough in the quantum measurement framework that is of the utmost interest from both a fundamental and an applicative point of view. In this Letter, we show how we realized for the first time a sequential weak value evaluation of two incompatible observables using a genuine single-photon experiment. These (sometimes anomalous) sequential weak values revealed the single-operator weak values, as well as the local correlation between them.

  8. On set-valued functionals: Multivariate risk measures and Aumann integrals

    NASA Astrophysics Data System (ADS)

    Ararat, Cagin

    particular, it is shown that a shortfall risk measure can be written as an intersection over a family of divergence risk measures indexed by a scalarization parameter. Examples include the multivariate versions of the entropic risk measure and the average value at risk. In the second part, Aumann integrals of set-valued functions on a measurable space are viewed as set-valued functionals and a Daniell-Stone type characterization theorem is proved for such functionals. More precisely, it is shown that a functional that maps measurable set-valued functions into a certain complete lattice of subsets of Rm can be written as the Aumann integral with respect to a measure if and only if the functional is (1) additive and (2) positively homogeneous, (3) it preserves decreasing limits, (4) it maps halfspace-valued functions to halfspaces, and (5) it maps shifted cone-valued functions to shifted cones. While the first three properties already exist in the classical Daniell-Stone theorem for the Lebesgue integral, the last two properties are peculiar to the set-valued framework and they suffice to complement the first three properties to identify a set-valued functional as the Aumann integral with respect to a measure.

  9. Developing a Measure of Value in Health Care.

    PubMed

    Ken Lee, K H; Matthew Austin, J; Pronovost, Peter J

    2016-06-01

    There is broad support to pay for value, rather than volume, for health care in the United States. Despite the support, practical approaches for measuring value remain elusive. Value is commonly defined as quality divided by costs, where quality reflects patient outcomes and costs are the total costs for providing care, whether these be costs related to an episode, a diagnosis, or per capita. Academicians have proposed a conceptual approach to measure value, in which we measure outcomes important to patients and costs using time-driven activity-based costing. This approach is conceptually sound, but has significant practical challenges. In our commentary, we describe how health care can use existing quality measures and cost accounting data to measure value. Although not perfect, we believe this approach is practical, valid, and scalable and can establish the foundation for future work in this area. Copyright © 2016 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  10. A Framework for Measuring Low-Value Care.

    PubMed

    Miller, George; Rhyan, Corwin; Beaudin-Seiler, Beth; Hughes-Cromwick, Paul

    2018-04-01

    It has been estimated that more than 30% of health care spending in the United States is wasteful, and that low-value care, which drives up costs unnecessarily while increasing patient risk, is a significant component of wasteful spending. To address the need for an ability to measure the magnitude of low-value care nationwide, identify the clinical services that are the greatest contributors to waste, and track progress toward eliminating low-value use of these services. Such an ability could provide valuable input to the efforts of policymakers and health systems to improve efficiency. We reviewed existing methods that could contribute to measuring low-value care and developed an integrated framework that combines multiple methods to comprehensively estimate and track the magnitude and principal sources of clinical waste. We also identified a process and needed research for implementing the framework. A comprehensive methodology for measuring and tracking low-value care in the United States would provide an important contribution toward reducing waste. Implementation of the framework described in this article appears feasible, and the proposed research program will allow moving incrementally toward full implementation while providing a near-term capability for measuring low-value care that can be enhanced over time. Copyright © 2018 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  11. Spectral dilation of L(B,H)-valued measures and its application to stationary dilation for Banach space valued processes

    NASA Technical Reports Server (NTRS)

    Miamee, A. G.

    1988-01-01

    Let B be a Banach space and H and K two Hilbert spaces. The spectral dilation of L(B,H)-valued measures is studied and it is shown that the recent results of Makagon and Salehi (1986) and Rosenberg (1982) on the dilation of L(K,H)-valued measures can be extended to hold for the general Banach space setting of L(B,H)-valued measures. These L(B,H)-valued measures are closely connected to the Banach space valued processes. This connection is recalled and as application of spectral dilation of L(B,H)-valued measures the well known stationary dilation results for scalar valued processes is extended to the case of Banach space valued processes.

  12. Weak measurements and quantum weak values for NOON states

    NASA Astrophysics Data System (ADS)

    Rosales-Zárate, L.; Opanchuk, B.; Reid, M. D.

    2018-03-01

    Quantum weak values arise when the mean outcome of a weak measurement made on certain preselected and postselected quantum systems goes beyond the eigenvalue range for a quantum observable. Here, we propose how to determine quantum weak values for superpositions of states with a macroscopically or mesoscopically distinct mode number, that might be realized as two-mode Bose-Einstein condensate or photonic NOON states. Specifically, we give a model for a weak measurement of the Schwinger spin of a two-mode NOON state, for arbitrary N . The weak measurement arises from a nondestructive measurement of the two-mode occupation number difference, which for atomic NOON states might be realized via phase contrast imaging and the ac Stark effect using an optical meter prepared in a coherent state. The meter-system coupling results in an entangled cat-state. By subsequently evolving the system under the action of a nonlinear Josephson Hamiltonian, we show how postselection leads to quantum weak values, for arbitrary N . Since the weak measurement can be shown to be minimally invasive, the weak values provide a useful strategy for a Leggett-Garg test of N -scopic realism.

  13. Linking Quality and Spending to Measure Value for People with Serious Illness.

    PubMed

    Ryan, Andrew M; Rodgers, Phillip E

    2018-03-01

    Healthcare payment is rapidly evolving to reward value by measuring and paying for quality and spending performance. Rewarding value for the care of seriously ill patients presents unique challenges. To evaluate the state of current efforts to measure and reward value for the care of seriously ill patients. We performed a PubMed search of articles related to (1) measures of spending for people with serious illness and (2) linking spending and quality measures and rewarding performance for the care of people with serious illness. We limited our search to U.S.-based studies published in English between January 1, 1960, and March 31, 2017. We supplemented this search by identifying public programs and other known initiatives that linked quality and spending for the seriously ill and extracted key program elements. Our search related to linking spending and quality measures and rewarding performance for the care of people with serious illness yielded 277 articles. We identified three current public programs that currently link measures of quality and spending-or are likely to within the next few years-the Oncology Care Model; the Comprehensive End-Stage Renal Disease Model; and Home Health Value-Based Purchasing. Models that link quality and spending consist of four core components: (1) measuring quality, (2) measuring spending, (3) the payment adjustment model, and (4) the linking/incentive model. We found that current efforts to reward value for seriously ill patients are targeted for specific patient populations, do not broadly encourage the use of palliative care, and have not closely aligned quality and spending measures related to palliative care. We develop recommendations for policymakers and stakeholders about how measures of spending and quality can be balanced in value-based payment programs.

  14. Linking Quality and Spending to Measure Value for People with Serious Illness

    PubMed Central

    Rodgers, Phillip E.

    2018-01-01

    Abstract Background: Healthcare payment is rapidly evolving to reward value by measuring and paying for quality and spending performance. Rewarding value for the care of seriously ill patients presents unique challenges. Objective: To evaluate the state of current efforts to measure and reward value for the care of seriously ill patients. Design: We performed a PubMed search of articles related to (1) measures of spending for people with serious illness and (2) linking spending and quality measures and rewarding performance for the care of people with serious illness. We limited our search to U.S.-based studies published in English between January 1, 1960, and March 31, 2017. We supplemented this search by identifying public programs and other known initiatives that linked quality and spending for the seriously ill and extracted key program elements. Results: Our search related to linking spending and quality measures and rewarding performance for the care of people with serious illness yielded 277 articles. We identified three current public programs that currently link measures of quality and spending—or are likely to within the next few years—the Oncology Care Model; the Comprehensive End-Stage Renal Disease Model; and Home Health Value-Based Purchasing. Models that link quality and spending consist of four core components: (1) measuring quality, (2) measuring spending, (3) the payment adjustment model, and (4) the linking/incentive model. We found that current efforts to reward value for seriously ill patients are targeted for specific patient populations, do not broadly encourage the use of palliative care, and have not closely aligned quality and spending measures related to palliative care. Conclusions: We develop recommendations for policymakers and stakeholders about how measures of spending and quality can be balanced in value-based payment programs. PMID:29091529

  15. Asymmetric behavior of the B(E2↑;0+ → 2+) values in 104-130Sn and generalized seniority

    NASA Astrophysics Data System (ADS)

    Maheshwari, Bhoomika; Jain, Ashok Kumar; Singh, Balraj

    2016-08-01

    We present freshly evaluated B (E 2 ↑ ;0+ →2+) values across the even-even Sn-isotopes which confirm the presence of an asymmetric behavior as well as a dip in the middle of the full valence space. We explain these features by using the concept of generalized seniority. The dip in the B (E 2) values near 116Sn is understood in terms of a change in the dominant orbits before and after the mid shell, which also explains the presence of asymmetric peaks in the B (E 2) values. This approach helps in deciding the most active valence spaces for a given set of isotopes, and single out the most useful truncation scheme for Large Scale Shell Model (LSSM) calculations. The LSSM calculations so guided by generalized seniority are also able to reproduce the experimental data on B (E 2) ↑ values quite well.

  16. An automated A-value measurement tool for accurate cochlear duct length estimation.

    PubMed

    Iyaniwura, John E; Elfarnawany, Mai; Ladak, Hanif M; Agrawal, Sumit K

    2018-01-22

    There has been renewed interest in the cochlear duct length (CDL) for preoperative cochlear implant electrode selection and postoperative generation of patient-specific frequency maps. The CDL can be estimated by measuring the A-value, which is defined as the length between the round window and the furthest point on the basal turn. Unfortunately, there is significant intra- and inter-observer variability when these measurements are made clinically. The objective of this study was to develop an automated A-value measurement algorithm to improve accuracy and eliminate observer variability. Clinical and micro-CT images of 20 cadaveric cochleae specimens were acquired. The micro-CT of one sample was chosen as the atlas, and A-value fiducials were placed onto that image. Image registration (rigid affine and non-rigid B-spline) was applied between the atlas and the 19 remaining clinical CT images. The registration transform was applied to the A-value fiducials, and the A-value was then automatically calculated for each specimen. High resolution micro-CT images of the same 19 specimens were used to measure the gold standard A-values for comparison against the manual and automated methods. The registration algorithm had excellent qualitative overlap between the atlas and target images. The automated method eliminated the observer variability and the systematic underestimation by experts. Manual measurement of the A-value on clinical CT had a mean error of 9.5 ± 4.3% compared to micro-CT, and this improved to an error of 2.7 ± 2.1% using the automated algorithm. Both the automated and manual methods correlated significantly with the gold standard micro-CT A-values (r = 0.70, p < 0.01 and r = 0.69, p < 0.01, respectively). An automated A-value measurement tool using atlas-based registration methods was successfully developed and validated. The automated method eliminated the observer variability and improved accuracy as compared to manual

  17. Complex Fuzzy Set-Valued Complex Fuzzy Measures and Their Properties

    PubMed Central

    Ma, Shengquan; Li, Shenggang

    2014-01-01

    Let F*(K) be the set of all fuzzy complex numbers. In this paper some classical and measure-theoretical notions are extended to the case of complex fuzzy sets. They are fuzzy complex number-valued distance on F*(K), fuzzy complex number-valued measure on F*(K), and some related notions, such as null-additivity, pseudo-null-additivity, null-subtraction, pseudo-null-subtraction, autocontionuous from above, autocontionuous from below, and autocontinuity of the defined fuzzy complex number-valued measures. Properties of fuzzy complex number-valued measures are studied in detail. PMID:25093202

  18. The Development and Validation of Brief and Ultrabrief Measures of Values.

    PubMed

    Sandy, Carson J; Gosling, Samuel D; Schwartz, Shalom H; Koelkebeck, Tim

    2017-01-01

    Values are a central personality construct and the importance of studying them has been well established. To encourage researchers to integrate measures of values into their studies, brief and ultrabrief instruments were developed to recapture the 10 values measured by the 40-item Portrait Values Questionnaire (PVQ; Schwartz, 2003 ). Rigorous psychometric procedures based on separate derivation (N = 38,049) and evaluation (N = 29,143) samples yielded 10- and 20-item measures of values, which proved to be successful at capturing the patterns and magnitude of correlations associated with the original PVQ. These instruments should be useful to researchers who would like to incorporate a values scale into their study but do not have the space to administer a longer measure.

  19. Cultural Values Predicting Acculturation Orientations: Operationalizing a Quantitative Measure

    ERIC Educational Resources Information Center

    Ehala, Martin

    2012-01-01

    This article proposes that acculturation orientations are related to two sets of cultural values: utilitarianism (Ut) and traditionalism (Tr). While utilitarian values enhance assimilation, traditional values support language and identity maintenance. It is proposed that the propensity to either end of this value opposition can be measured by an…

  20. Measuring Value in Internal Medicine Residency Training Hospitals Using Publicly Reported Measures.

    PubMed

    Schickedanz, Adam; Gupta, Reshma; Arora, Vineet M; Braddock, Clarence H

    2018-03-01

    Graduate medical education (GME) lacks measures of resident preparation for high-quality, cost-conscious practice. The authors used publicly reported teaching hospital value measures to compare internal medicine residency programs on high-value care training and to validate these measures against program director perceptions of value. Program-level value training scores were constructed using Centers for Medicare & Medicaid Services Value-Based Purchasing (VBP) Program hospital quality and cost-efficiency data. Correlations with Association of Program Directors in Internal Medicine Annual Survey high-value care training measures were examined using logistic regression. For every point increase in program-level VBP score, residency directors were more likely to agree that GME programs have a responsibility to contain health care costs (adjusted odds ratio [aOR] 1.18, P = .04), their faculty model high-value care (aOR 1.07, P = .03), and residents are prepared to make high-value medical decisions (aOR 1.07, P = .09). Publicly reported clinical data offer valid measures of GME value training.

  1. A Value Measure for Public-Sector Enterprise Risk Management: A TSA Case Study.

    PubMed

    Fletcher, Kenneth C; Abbas, Ali E

    2018-05-01

    This article presents a public value measure that can be used to aid executives in the public sector to better assess policy decisions and maximize value to the American people. Using Transportation Security Administration (TSA) programs as an example, we first identify the basic components of public value. We then propose a public value account to quantify the outcomes of various risk scenarios, and we determine the certain equivalent of several important TSA programs. We illustrate how this proposed measure can quantify the effects of two main challenges that government organizations face when conducting enterprise risk management: (1) short-term versus long-term incentives and (2) avoiding potential negative consequences even if they occur with low probability. Finally, we illustrate how this measure enables the use of various tools from decision analysis to be applied in government settings, such as stochastic dominance arguments and certain equivalent calculations. Regarding the TSA case study, our analysis demonstrates the value of continued expansion of the TSA trusted traveler initiative and increasing the background vetting for passengers who are afforded expedited security screening. © 2017 Society for Risk Analysis.

  2. A framework to measure the value of public health services.

    PubMed

    Jacobson, Peter D; Neumann, Peter J

    2009-10-01

    To develop a framework that public health practitioners could use to measure the value of public health services. Primary data were collected from August 2006 through March 2007. We interviewed (n=46) public health practitioners in four states, leaders of national public health organizations, and academic researchers. Using a semi-structured interview protocol, we conducted a series of qualitative interviews to define the component parts of value for public health services and identify methodologies used to measure value and data collected. The primary form of analysis is descriptive, synthesizing information across respondents as to how they measure the value of their services. Our interviews did not reveal a consensus on how to measure value or a specific framework for doing so. Nonetheless, the interviews identified some potential strategies, such as cost accounting and performance-based contracting mechanisms. The interviews noted implementation barriers, including limits to staff capacity and data availability. We developed a framework that considers four component elements to measure value: external factors that must be taken into account (i.e., mandates); key internal actions that a local health department must take (i.e., staff assessment); using appropriate quantitative measures; and communicating value to elected officials and the public.

  3. Intensity-Value Corrections for Integrating Sphere Measurements of Solid Samples Measured Behind Glass

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Johnson, Timothy J.; Bernacki, Bruce E.; Redding, Rebecca L.

    2014-11-01

    Accurate and calibrated directional-hemispherical reflectance spectra of solids are important for both in situ and remote sensing. Many solids are in the form of powders or granules and to measure their diffuse reflectance spectra in the laboratory, it is often necessary to place the samples behind a transparent medium such as glass for the ultraviolet (UV), visible, or near-infrared spectral regions. Using both experimental methods and a simple optical model, we demonstrate that glass (fused quartz in our case) leads to artifacts in the reflectance values. We report our observations that the measured reflectance values, for both hemispherical and diffusemore » reflectance, are distorted by the additional reflections arising at the air–quartz and sample–quartz interfaces. The values are dependent on the sample reflectance and are offset in intensity in the hemispherical case, leading to measured values up to ~6% too high for a 2% reflectance surface, ~3.8% too high for 10% reflecting surfaces, approximately correct for 40–60% diffuse-reflecting surfaces, and ~1.5% too low for 99% reflecting Spectralon® surfaces. For the case of diffuse-only reflectance, the measured values are uniformly too low due to the polished glass, with differences of nearly 6% for a 99% reflecting matte surface. The deviations arise from the added reflections from the quartz surfaces, as verified by both theory and experiment, and depend on sphere design. Finally, empirical correction factors were implemented into post-processing software to redress the artifact for hemispherical and diffuse reflectance data across the 300–2300 nm range.« less

  4. Dollar$ & $en$e. Part IV: Measuring the value of people, structural, and customer capital.

    PubMed

    Wilkinson, I

    2001-01-01

    In Part I of this series, I introduced the concept of memes (1). Memes are ideas or concepts, the information world equivalent of genes. The goal of this series of articles is to infect you with my memes, so that you will assimilate, translate, and express them. We discovered that no matter what our area of expertise or "-ology," we all are in the information business. Our goal is to be in the wisdom business. We saw that when we convert raw data into wisdom we are moving along a value chain. Each step in the chain adds a different amount of value to the final product: timely, relevant, accurate, and precise knowledge which can then be applied to create the ultimate product in the value chain: wisdom. In Part II of this series, I infected you with a set of memes for measuring the cost of adding value (2). In Part III of this series, I infected you with a new set of memes for measuring the added value of knowledge, i.e., intellectual capital (3). In Part IV of this series, I will infect you with memes for measuring the value of people, structural, and customer capital.

  5. Calculated and measured [Ca(2+)] in buffers used to calibrate Ca(2+) macroelectrodes.

    PubMed

    McGuigan, John A S; Stumpff, Friederike

    2013-05-01

    The ionized concentration of calcium in physiological buffers ([Ca(2+)]) is normally calculated using either tabulated constants or software programs. To investigate the accuracy of such calculations, the [Ca(2+)] in EGTA [ethylene glycol-bis(β-aminoethylether)-N,N,N|,N|-tetraacetic acid], BAPTA [1,2-bis(o-aminophenoxy) ethane-N,N,N|,N|-tetraacetic acid], HEDTA [N-(2-hydroxyethyl)-ethylenediamine-N,N|,N|-triacetic acid], and NTA [N,N-bis(carboxymethyl)glycine] buffers was estimated using the ligand optimization method, and these measured values were compared with calculated values. All measurements overlapped in the pCa range of 3.51 (NTA) to 8.12 (EGTA). In all four buffer solutions, there was no correlation between measured and calculated values; the calculated values differed among themselves by factors varying from 1.3 (NTA) to 6.9 (EGTA). Independent measurements of EGTA purity and the apparent dissociation constants for HEDTA and NTA were not significantly different from the values estimated by the ligand optimization method, further substantiating the method. Using two calibration solutions of pCa 2.0 and 3.01 and seven buffers in the pCa range of 4.0-7.5, calibration of a Ca(2+) electrode over the pCa range of 2.0-7.5 became a routine procedure. It is proposed that such Ca(2+) calibration/buffer solutions be internationally defined and made commercially available to allow the precise measurement of [Ca(2+)] in biology. Copyright © 2013 Elsevier Inc. All rights reserved.

  6. A Scaled-Projective Measure of Interpersonal Values

    ERIC Educational Resources Information Center

    Kilmann, Ralph H.

    1975-01-01

    The Kilmann Insight Test is a measure of the interpersonal value constructs. That is how the individual perceives and interprets the desirable and undesirable features of interpersonal behavior. The validity of the test is investigated by explaining its relationship to a self-report measure assessing similar values. (DEP)

  7. Effects of variation in background mixing ratios of N2, O2, and Ar on the measurement of δ18O-H2O and δ2H-H2O values by cavity ring-down spectroscopy

    NASA Astrophysics Data System (ADS)

    Johnson, Jennifer E.; Rella, Chris W.

    2017-08-01

    Cavity ring-down spectrometers have generally been designed to operate under conditions in which the background gas has a constant composition. However, there are a number of observational and experimental situations of interest in which the background gas has a variable composition. In this study, we examine the effect of background gas composition on a cavity ring-down spectrometer that measures δ18O-H2O and δ2H-H2O values based on the amplitude of water isotopologue absorption features around 7184 cm-1 (L2120-i, Picarro, Inc.). For background mixtures balanced with N2, the apparent δ18O values deviate from true values by -0.50 ± 0.001 ‰ O2 %-1 and -0.57 ± 0.001 ‰ Ar %-1, and apparent δ2H values deviate from true values by 0.26 ± 0.004 ‰ O2 %-1 and 0.42 ± 0.004 ‰ Ar %-1. The artifacts are the result of broadening, narrowing, and shifting of both the target absorption lines and strong neighboring lines. While the background-induced isotopic artifacts can largely be corrected with simple empirical or semi-mechanistic models, neither type of model is capable of completely correcting the isotopic artifacts to within the inherent instrument precision. The development of strategies for dynamically detecting and accommodating background variation in N2, O2, and/or Ar would facilitate the application of cavity ring-down spectrometers to a new class of observations and experiments.

  8. [Implicit value judgments in the measurement of health inequalities].

    PubMed

    Harper, Sam; King, Nicholas B; Meersman, Stephen C; E Reichman, Marsha; Breen, Nancy; Lynch, John

    2014-04-01

    Quantitative estimates of the magnitude, direction, and rate of change of health inequalities play a crucial role in creating and assessing policies aimed at eliminating the disproportionate burden of disease in disadvantaged populations. It is generally assumed that the measurement of health inequalities is a value-neutral process, providing objective data that are then interpreted using normative judgments about whether a particular distribution of health is just, fair, or socially acceptable. We discuss five examples in which normative judgments play a role in the measurement process itself, through either the selection of one measurement strategy to the exclusion of others or the selection of the type, significance, or weight assigned to the variables being measured. Overall, we find that many commonly used measures of inequality are value laden and that the normative judgments implicit in these measures have important consequences for interpreting and responding to health inequalities. Because values implicit in the generation of health inequality measures may lead to radically different interpretations of the same underlying data,we urge researchers to explicitly consider and transparently discuss the normative judgments underlying their measures. We also urge policymakers and other consumers of health inequalities data to pay close attention to the measures on which they base their assessments of current and future health policies.

  9. Implicit value judgments in the measurement of health inequalities.

    PubMed

    Harper, Sam; King, Nicholas B; Meersman, Stephen C; Reichman, Marsha E; Breen, Nancy; Lynch, John

    2010-03-01

    Quantitative estimates of the magnitude, direction, and rate of change of health inequalities play a crucial role in creating and assessing policies aimed at eliminating the disproportionate burden of disease in disadvantaged populations. It is generally assumed that the measurement of health inequalities is a value-neutral process, providing objective data that are then interpreted using normative judgments about whether a particular distribution of health is just, fair, or socially acceptable. We discuss five examples in which normative judgments play a role in the measurement process itself, through either the selection of one measurement strategy to the exclusion of others or the selection of the type, significance, or weight assigned to the variables being measured. Overall, we find that many commonly used measures of inequality are value laden and that the normative judgments implicit in these measures have important consequences for interpreting and responding to health inequalities. Because values implicit in the generation of health inequality measures may lead to radically different interpretations of the same underlying data, we urge researchers to explicitly consider and transparently discuss the normative judgments underlying their measures. We also urge policymakers and other consumers of health inequalities data to pay close attention to the measures on which they base their assessments of current and future health policies.

  10. Liver Stiffness Measured by Two-Dimensional Shear-Wave Elastography: Prognostic Value after Radiofrequency Ablation for Hepatocellular Carcinoma.

    PubMed

    Lee, Dong Ho; Lee, Jeong Min; Yoon, Jung-Hwan; Kim, Yoon Jun; Lee, Jeong-Hoon; Yu, Su Jong; Han, Joon Koo

    2018-03-01

    To evaluate the prognostic value of liver stiffness (LS) measured using two-dimensional (2D) shear-wave elastography (SWE) in patients with hepatocellular carcinoma (HCC) treated by radiofrequency ablation (RFA). The Institutional Review Board approved this retrospective study and informed consent was obtained from all patients. A total of 134 patients with up to 3 HCCs ≤5 cm who had undergone pre-procedural 2D-SWE prior to RFA treatment between January 2012 and December 2013 were enrolled. LS values were measured using real-time 2D-SWE before RFA on the procedural day. After a mean follow-up of 33.8 ± 9.9 months, we analyzed the overall survival after RFA using the Kaplan-Meier method and Cox proportional hazard regression model. The optimal cutoff LS value to predict overall survival was determined using the minimal p value approach. During the follow-up period, 22 patients died, and the estimated 1- and 3-year overall survival rates were 96.4 and 85.8%, respectively. LS measured by 2D-SWE was found to be a significant predictive factor for overall survival after RFA of HCCs, as was the presence of extrahepatic metastases. As for the optimal cutoff LS value for the prediction of overall survival, it was determined to be 13.3 kPa. In our study, 71 patients had LS values ≥13.3 kPa, and the estimated 3-year overall survival was 76.8% compared to 96.3% in 63 patients with LS values <13.3 kPa. This difference was statistically significant (hazard ratio = 4.30 [1.26-14.7]; p = 0.020). LS values measured by 2D-SWE was a significant predictive factor for overall survival after RFA for HCC.

  11. Direct quantum process tomography via measuring sequential weak values of incompatible observables.

    PubMed

    Kim, Yosep; Kim, Yong-Su; Lee, Sang-Yun; Han, Sang-Wook; Moon, Sung; Kim, Yoon-Ho; Cho, Young-Wook

    2018-01-15

    The weak value concept has enabled fundamental studies of quantum measurement and, recently, found potential applications in quantum and classical metrology. However, most weak value experiments reported to date do not require quantum mechanical descriptions, as they only exploit the classical wave nature of the physical systems. In this work, we demonstrate measurement of the sequential weak value of two incompatible observables by making use of two-photon quantum interference so that the results can only be explained quantum physically. We then demonstrate that the sequential weak value measurement can be used to perform direct quantum process tomography of a qubit channel. Our work not only demonstrates the quantum nature of weak values but also presents potential new applications of weak values in analyzing quantum channels and operations.

  12. Effects of caffeine on fractional flow reserve values measured using intravenous adenosine triphosphate.

    PubMed

    Nakayama, Masafumi; Chikamori, Taishiro; Uchiyama, Takashi; Kimura, Yo; Hijikata, Nobuhiro; Ito, Ryosuke; Yuhara, Mikio; Sato, Hideaki; Kobori, Yuichi; Yamashina, Akira

    2018-04-01

    We investigated the effects of caffeine intake on fractional flow reserve (FFR) values measured using intravenous adenosine triphosphate (ATP) before cardiac catheterization. Caffeine is a competitive antagonist for adenosine receptors; however, it is unclear whether this antagonism affects FFR values. Patients were evenly randomized into 2 groups preceding the FFR study. In the caffeine group (n = 15), participants were given coffee containing 222 mg of caffeine 2 h before the catheterization. In the non-caffeine group (n = 15), participants were instructed not to take any caffeine-containing drinks or foods for at least 12 h before the catheterization. FFR was performed in patients with more than intermediate coronary stenosis using the intravenous infusion of ATP at 140 μg/kg/min (normal dose) and 170 μg/kg/min (high dose), and the intracoronary infusion of papaverine. FFR was followed for 30 s after maximal hyperemia. In the non-caffeine group, the FFR values measured with ATP infusion were not significantly different from those measured with papaverine infusion. However, in the caffeine group, the FFR values were significantly higher after ATP infusion than after papaverine infusion (P = 0.002 and P = 0.007, at normal and high dose ATP vs. papaverine, respectively). FFR values with ATP infusion were significantly increased 30 s after maximal hyperemia (P = 0.001 and P < 0.001 for normal and high dose ATP, respectively). The stability of the FFR values using papaverine showed no significant difference between the 2 groups. Caffeine intake before the FFR study affected FFR values and their stability. These effects could not be reversed by an increased ATP dose.

  13. Elevated phosphodiester and T2 levels can be measured in the absence of fat infiltration in Duchenne muscular dystrophy patients.

    PubMed

    Hooijmans, M T; Niks, E H; Burakiewicz, J; Verschuuren, J J G M; Webb, A G; Kan, H E

    2017-01-01

    Quantitative MRI and MRS are increasingly important as non-invasive outcome measures in therapy development for Duchenne muscular dystrophy (DMD). Many studies have focussed on individual measures such as fat fraction and metabolite levels in relation to age and functionality, but much less attention has been given to how these indices relate to each other. Here, we assessed spatially resolved metabolic changes in leg muscles of DMD patients, and classified muscles according to the degree of fat replacement compared with healthy controls. Quantitative MRI (three-point Dixon and multi-spin echo without fat suppression and a tri-exponential fit) and 2D-CSI 31 P MRS scans were obtained from 18 DMD patients and 12 healthy controls using a 3 T and a 7 T MR scanner. Metabolite levels, T 2 values and fat fraction were individually assessed for five lower leg muscles. In muscles with extensive fat replacement, phosphodiester over adenosine triphosphate (PDE/ATP), inorganic phosphate over phosphocreatine, intracellular tissue pH and T 2 were significantly increased compared with healthy controls. In contrast, in muscles without extensive fat replacement, only PDE/ATP and T 2 values were significantly elevated. Overall, our results show that PDE levels and T 2 values increase prior to the occurrence of fat replacement and remain elevated in later stages of the disease. This suggests that these individual measures could not only function as early markers for muscle damage but also reflect potentially reversible pathology in the more advanced stages. Copyright © 2016 John Wiley & Sons, Ltd.

  14. Interferometric measurement of the 1S/sub 1/2/-2S/sub 1/2/ transition frequency in atomic hydrogen

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barr, J.R.M.; Girkin, J.M.; Tolchard, J.M.

    The 1S/sub 1/2/-2S/sub 1/2/ transition frequency in atomic hydrogen has been interferometrically measured by comparison with a reference line in /sup 130/Te/sub 2/ by Doppler-free two-photon laser spectroscopy. The measured 1S/sub 1/2/-2S/sub 1/2/ transition frequency of 2 466 061 397(25) MHz is in good agreement with the theoretical predictions of Erickson modified to take account of recent measurements of the Rydberg constant. This measurement can be used to deduce a value for the ground-state Lamb shift and gives the result of 8182(25) MHz which compares with a value of 8173.248(81) MHz predicted by Erickson.

  15. Measuring Nursing Value from the Electronic Health Record.

    PubMed

    Welton, John M; Harper, Ellen M

    2016-01-01

    We report the findings of a big data nursing value expert group made up of 14 members of the nursing informatics, leadership, academic and research communities within the United States tasked with 1. Defining nursing value, 2. Developing a common data model and metrics for nursing care value, and 3. Developing nursing business intelligence tools using the nursing value data set. This work is a component of the Big Data and Nursing Knowledge Development conference series sponsored by the University Of Minnesota School Of Nursing. The panel met by conference calls for fourteen 1.5 hour sessions for a total of 21 total hours of interaction from August 2014 through May 2015. Primary deliverables from the bit data expert group were: development and publication of definitions and metrics for nursing value; construction of a common data model to extract key data from electronic health records; and measures of nursing costs and finance to provide a basis for developing nursing business intelligence and analysis systems.

  16. Patients’ perceived value of pharmacy quality measures: a mixed-methods study

    PubMed Central

    Shiyanbola, Olayinka O; Mort, Jane R

    2015-01-01

    Objective To describe patients’ perceived value and use of quality measures in evaluating and choosing community pharmacies. Design Focus group methodology was combined with a survey tool. During the focus groups, participants assessed the value of the Pharmacy Quality Alliance's quality measures in evaluating and choosing a pharmacy. Also, participants completed questionnaires rating their perceived value of quality measures in evaluating a pharmacy (1 being low value and 5 being high) or choosing a pharmacy (yes/no). Thematic analysis and descriptive statistics were used to analyse the focus groups and surveys, respectively. Setting Semistructured focus groups were conducted in a private meeting space of an urban and a rural area of a Mid-western State in the USA. Participants Thirty-four adults who filled prescription medications in community pharmacies for a chronic illness were recruited in community pharmacies, senior centres and public libraries. Results While comments indicated that all measures were important, medication safety measures (eg, drug-drug interactions) were valued more highly than others. Rating of quality measure utility in evaluating a pharmacy ranged from a mean of 4.88 (‘drug-drug interactions’) to a mean of 4.0 (‘absence of controller therapy for patients with asthma’). Patients were hesitant to use quality information in choosing a pharmacy (depending on the participant's location) but might consider if moving to a new area or having had a negative pharmacy experience. Use of select quality measures to choose a pharmacy ranged from 97.1% of participants using ‘drug-drug interactions’ (medication safety measure) to 55.9% using ‘absence of controller therapy for patients with asthma’. Conclusions The study participants valued quality measures in evaluating and selecting a community pharmacy, with medication safety measures valued highest. The participants reported that the quality measures would not typically cause a

  17. Reference Values for Cardiorespiratory Fitness and Incidence of Type 2 Diabetes

    PubMed Central

    Kawakami, Ryoko; Sawada, Susumu S.; Matsushita, Munehiro; Okamoto, Takashi; Tsukamoto, Koji; Higuchi, Mitsuru; Miyachi, Motohiko

    2014-01-01

    Background In “Physical Activity Reference for Health Promotion 2013” the Japan Ministry of Health, Labour and Welfare publication gives reference values for cardiorespiratory fitness (CRF) required for good health. We examined the associations between the CRF reference values and incidence of type 2 diabetes. Methods This prospective cohort study enrolled 4633 nondiabetic Japanese men aged 20 to 39 years at baseline. CRF was measured using the cycle ergometer test, and maximal oxygen uptake was estimated. On the basis of the CRF reference value, participants were classified into 2 groups: those with values less than the reference value (under-RV) and those with values equal to or greater than reference value (over-RV). Hazard ratios (HRs) and 95% CIs for incident type 2 diabetes were estimated using a Cox proportional hazards model. Results A total of 266 participants developed type 2 diabetes during the 14 years of follow-up. As compared with the under-RV group, the over-RV group had a significantly lower multivariable-adjusted HR for type 2 diabetes (HR 0.67; 95% CI, 0.51–0.89). In receiver operating characteristic analysis, the optimal CRF cut-off value for predicting incident type 2 diabetes was 10.8 metabolic equivalents (sensitivity, 0.64; specificity, 0.64), which was close to the CRF reference value of 11.0 metabolic equivalents. Conclusions The reference CRF value appears to be reasonably valid for prevention of type 2 diabetes, especially among Japanese men younger than 40 years. Development of type 2 diabetes can be prevented by maintaining a CRF level above the reference value. PMID:24240630

  18. Infrared end-tidal CO2 measurement does not accurately predict arterial CO2 values or end-tidal to arterial PCO2 gradients in rabbits with lung injury.

    PubMed

    Hopper, A O; Nystrom, G A; Deming, D D; Brown, W R; Peabody, J L

    1994-03-01

    End-tidal PCO2 (PETCO2) measurements from two commercially available neonatal infrared capnometers with different sampling systems and a mass spectrometer were compared with arterial PCO2 (PaCO2) to determine whether the former could predict the latter in mechanically ventilated rabbits with and without lung injury. The effects of tidal volume, ventilator frequency and type of lung injury on the gradient between PETCO2 and PaCO2 (delta P(a-ET)CO2) were evaluated. Twenty rabbits were studied: 10 without lung injury, 5 with saline lavage and 5 with lung injury by meconium instillation. Paired measurements of PETCO2 by two infrared capnometers and a mass spectrometer were compared to PaCO2. In the rabbits without lung injury, the values from the infrared capnometers and mass spectrometer correlated strongly with PaCO2 (r > or = 0.91) despite differences in the slopes of the linear regression between PETCO2 and PaCO2 and in delta P(a-ET)CO2 (P < 0.05). Values from the mainstream IR-capnometer more closely approximated the line of identity than the regression between the sidestream IR-capnometer values or the mass spectrometer and PaCO2, but tended to overestimate PaCO2. The delta P(a-ET)CO2 was similar at all tidal volumes and ventilator frequencies, regardless of capnometer type. In the rabbits with induced lung injury, while there was a positive correlation between the slopes of the regression between PETCO2 and PaCO2 for both capnometers (r > or = 0.70), none of the regression slopes approximated the line of identity. The delta P(a-ET)CO2 was greater in rabbits with injured than noninjured lungs (P < 0.05). The delta P(a-ET)CO2 was similar among capnometers regardless of tidal volume, ventilator frequency, or type of lung injury. The 95% confidence interval of plots PaCO2 against PETCO2 was large for rabbits with injured and noninjured lungs.(ABSTRACT TRUNCATED AT 250 WORDS)

  19. Precision Measurements of the B(E1) Strengths in 11Be

    NASA Astrophysics Data System (ADS)

    Kwan, E.; Wu, C. Y.; Summers, N. C.; Hackman, G.; Drake, T. E.; Andreoiu, C.; Ashley, R.; Ball, G. C.; Bender, P. C.; Boston, A. J.; Boston, H. C.; Chester, A.; Close, A.; Cline, D.; Cross, D. S.; Dunlop, R.; Finley, A.; Garnsworthy, A.; Hayes, A. B.; Laffoley, A. T.; Nano, T.; Navrátil, P.; Pearson, C. J.; Pore, J.; Starosta, K.; Thompson, I. J.; Voss, P.; Williams, S. J.; Wang, Z. M.

    2014-09-01

    The electromagnetic transition strength between the two bound states were measured in the one-neutron halo nucleus 11Be from Coulomb excitation on 196Pt at projectile energies of 1.727 and 2.086 MeV/nucleon at TRIUMF. A B(E1) strength of 0.102(2) e2fm2, deduced from the forward-scattering data, is consistent with previous Coulomb excitation measurements at intermediate projectile energies with a model-dependent analysis.

  20. A measurement of the proton structure function F2( x, Q2) at low x and low Q2 at HERA

    NASA Astrophysics Data System (ADS)

    Adloff, C.; Aid, S.; Anderson, M.; Andreev, V.; Andrieu, B.; Arkadov, V.; Arndt, C.; Ayyaz, I.; Babaev, A.; Bähr, J.; Bán, J.; Ban, Y.; Baranov, P.; Barrelet, E.; Barschke, R.; Bartel, W.; Bassler, U.; Beck, H. P.; Beck, M.; Behrend, H.-J.; Belousov, A.; Berger, Ch.; Bernardi, G.; Bertrand-Coremans, G.; Beyer, R.; Biddulph, P.; Bispham, P.; Bizot, J. C.; Borras, K.; Botterweck, F.; Boudry, V.; Bourov, S.; Braemer, A.; Braunschweig, W.; Brisson, V.; Brückner, W.; Bruel, P.; Bruncko, D.; Brune, C.; Buchholz, R.; Büngener, L.; Bürger, J.; Büsser, F. W.; Buniatian, A.; Burke, S.; Burton, M. J.; Buschhorn, G.; Calvet, D.; Campbell, A. J.; Carli, T.; Charlet, M.; Clarke, D.; Clerbaux, B.; Cocks, S.; Contreras, J. G.; Cormack, C.; Coughlan, J. A.; Courau, A.; Cousinou, M.-C.; Cox, B. E.; Cozzika, G.; Cussans, D. G.; Cvach, J.; Dagoret, S.; Dainton, J. B.; Dau, W. D.; Daum, K.; David, M.; Davis, C. L.; De Roeck, A.; De Wolf, E. A.; Delcourt, B.; Dirkmann, M.; Dixon, P.; Dlugosz, W.; Dollfus, C.; Donovan, K. T.; Dowell, J. D.; Dreis, H. B.; Droutskoi, A.; Ebert, J.; Ebert, T. R.; Eckerlin, G.; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Eisenhandler, E.; Elsen, E.; Erdmann, M.; Fahr, A. B.; Favart, L.; Fedotov, A.; Felst, R.; Feltesse, J.; Ferencei, J.; Ferrarotto, F.; Flamm, K.; Fleischer, M.; Flieser, M.; Flügge, G.; Fomenko, A.; Formánek, J.; Foster, J. M.; Franke, G.; Gabathuler, E.; Gabathuler, K.; Gaede, F.; Garvey, J.; Gayler, J.; Gebauer, M.; Genzel, H.; Gerhards, R.; Glazov, A.; Goerlich, L.; Gogitidze, N.; Goldberg, M.; Goldner, D.; Golec-Biernat, K.; Gonzalez-Pineiro, B.; Gorelov, I.; Grab, C.; Grässler, H.; Greenshaw, T.; Griffiths, R. K.; Grindhammer, G.; Gruber, A.; Gruber, C.; Hadig, T.; Haidt, D.; Hajduk, L.; Haller, T.; Hampel, M.; Haynes, W. J.; Heinemann, B.; Heinzelmann, G.; Henderson, R. C. W.; Henschel, H.; Herynek, I.; Hess, M. F.; Hewitt, K.; Hiller, K. H.; Hilton, C. D.; Hladký, J.; Höppner, M.; Hoffmann, D.; Holtom, T.; Horisberger, R.; Hudgson, V. L.; Hütte, M.; Ibbotson, M.; İşsever, Ç.; Itterbeck, H.; Jacholkowska, A.; Jacobsson, C.; Jacquet, M.; Jaffre, M.; Janoth, J.; Jansen, D. M.; Jönsson, L.; Johnson, D. P.; Jung, H.; Kalmus, P. I. P.; Kander, M.; Kant, D.; Kathage, U.; Katzy, J.; Kaufmann, H. H.; Kaufmann, O.; Kausch, M.; Kazarian, S.; Kenyon, I. R.; Kermiche, S.; Keuker, C.; Kiesling, C.; Klein, M.; Kleinwort, C.; Knies, G.; Köhler, T.; Köhne, J. H.; Kolanoski, H.; Kolya, S. D.; Korbel, V.; Kostka, P.; Kotelnikov, S. K.; Krämerkämper, T.; Krasny, M. W.; Krehbiel, H.; Krücker, D.; Küpper, A.; Küster, H.; Kuhlen, M.; Kurča, T.; Kurzhöfer, J.; Laforge, B.; Landon, M. P. J.; Lange, W.; Langenegger, U.; Lebedev, A.; Lehner, F.; Lemaitre, V.; Levonian, S.; Lindstroem, M.; Linsel, F.; Lipinski, J.; List, B.; Lobo, G.; Lomas, J. W.; Lopez, G. C.; Lubimov, V.; Lüke, D.; Lytkin, L.; Magnussen, N.; Mahlke-Krüger, H.; Malinovski, E.; Maraček, R.; Marage, P.; Marks, J.; Marshall, R.; Martens, J.; Martin, G.; Martin, R.; Martyn, H.-U.; Martyniak, J.; Mavroidis, T.; Maxfield, S. J.; McMahon, S. J.; Mehta, A.; Meier, K.; Merkel, P.; Metlica, F.; Meyer, A.; Meyer, A.; Meyer, H.; Meyer, J.; Meyer, P.-O.; Migliori, A.; Mikocki, S.; Milstead, D.; Moeck, J.; Moreau, F.; Morris, J. V.; Mroczko, E.; Müller, D.; Walter, T.; Müller, K.; Murín, P.; Nagovizin, V.; Nahnhauer, R.; Naroska, B.; Naumann, Th.; Négri, I.; Newman, P. R.; Newton, D.; Nguyen, H. K.; Nicholls, T. C.; Niebergall, F.; Niebuhr, C.; Niedzballa, Ch.; Niggli, H.; Nowak, G.; Nunnemann, T.; Nyberg-Werther, M.; Oberlack, H.; Olsson, J. E.; Ozerov, D.; Palmen, P.; Panaro, E.; Panitch, A.; Pascaud, C.; Passaggio, S.; Patel, G. D.; Pawletta, H.; Peppel, E.; Perez, E.; Phillips, J. P.; Pieuchot, A.; Pitzl, D.; Pöschl, R.; Pope, G.; Povh, B.; Prell, S.; Rabbertz, K.; Rädel, G.; Reimer, P.; Rick, H.; Riess, S.; Rizvi, E.; Robmann, P.; Roosen, R.; Rosenbauer, K.; Rostovtsev, A.; Rouse, F.; Royon, C.; Rüter, K.; Rusakov, S.; Rybicki, K.; Sankey, D. P. C.; Schacht, P.; Schiek, S.; Schleif, S.; Schleper, P.; von Schlippe, W.; Schmidt, D.; Schmidt, G.; Schoeffel, L.; Schöning, A.; Schröder, V.; Schuhmann, E.; Schwab, B.; Sefkow, F.; Semenov, A.; Shekelyan, V.; Sheviakov, I.; Shtarkov, L. N.; Siegmon, G.; Siewert, U.; Sirois, Y.; Skillicorn, I. O.; Sloan, T.; Smirnov, P.; Smith, M.; Solochenko, V.; Soloviev, Y.; Specka, A.; Spiekermann, J.; Spielman, S.; Spitzer, H.; Squinabol, F.; Steffen, P.; Steinberg, R.; Steinhart, J.; Stella, B.; Stellberger, A.; Stier, J.; Stiewe, J.; Stöβlein, U.; Stolze, K.; Straumann, U.; Struczinski, W.; Sutton, J. P.; Tapprogge, S.; Taševský, M.; Tchernyshov, V.; Tchetchelnitski, S.; Theissen, J.; Thompson, G.; Thompson, P. D.; Tobien, N.; Todenhagen, R.; Truöl, P.; Tsipolitis, G.; Turnau, J.; Tzamariudaki, E.; Uelkes, P.; Usik, A.; Valkár, S.; Valkárová, A.; Valĺee, C.; Van Esch, P.; Van Mechelen, P.; Vandenplas, D.; Vazdik, Y.; Verrecchia, P.; Villet, G.; Wacker, K.; Wagener, A.; Wagener, M.; Wallny, R.; Waugh, B.; Weber, G.; Weber, M.; Wegener, D.; Wegner, A.; Wengler, T.; Werner, M.; West, L. R.; Wiesand, S.; Wilksen, T.; Willard, S.; Winde, M.; Winter, G.-G.; Wittek, C.; Wobisch, M.; Wollatz, H.; Wünsch, E.; Žáček, J.; Zarbock, D.; Zhang, Z.; Zhokin, A.; Zini, P.; Zomer, F.; Zsembery, J.; zurNedden, M.; H1 Collaboration

    1997-02-01

    The results of a measurement of the proton structure function F2( x, Q2) and the virtual photon-proton cross section are reported for momentum transfers squared Q2 between 0.35 GeV 2 and 3.5 GeV 2 and for Bjorken- x values down to 6 × 10 -6 using data collected by the HERA experiment H1 in 1995. The data represent an increase in kinematic reach to lower x and Q2 values of about a factor of 5 compared to previous H1 measurements. Including measurements from fixed target experiments the rise of F2 with decreasing x is found to be less steep for the lowest Q2 values measured. Phenomenological models at low Q2 are compared with the data.

  1. Accuracy of apparent diffusion coefficient value measurement on PACS workstation: A comparative analysis.

    PubMed

    El Kady, Reem M; Choudhary, Arabinda Kumar; Tappouni, Rafel

    2011-03-01

    The purpose of this article is to evaluate the accuracy of apparent diffusion coefficient (ADC) measurements made with a PACS workstation compared with measurements made with a dedicated workstation, which is currently considered the reference standard. A retrospective review was performed in liver lesions from 79 patients using three MRI platforms. The final diagnosis was established by liver biopsy in 31 patients and by dynamic MRI and follow-up, both clinical and radiologic as indicated, in 48 patients. Each lesion that was clearly demonstrable on the ADC map was measured with a commercial dedicated postprocessing workstation and again with a PACS system. A two-sample t test was used to determine the statistically significant differences between the two ADC measurements. A total of 79 patients with 120 liver lesions were included. ADC values measured on the workstation were 0.4-4.38 × 10(-3) mm(2)/s. The ADC values measured on the PACS were 0.42-4.35 × 10(-3) mm(2)/s. The T value was -1.113, with 119 degrees of freedom, and the significance level was 0.268, which implies no significant difference between the two different measuring systems for all pathologic abnormalities and MRI scanners used. ADC values measured on a routine PACS workstation are as accurate as the values obtained on a dedicated specialized workstation. ADC value measurement on the routine PACS will save time and lead to increased utilization, which, in turn, will lead to an improved understanding of the different disease processes and their clinical management.

  2. Comparison of measurement- and proxy-based Vs30 values in California

    USGS Publications Warehouse

    Yong, Alan K.

    2016-01-01

    This study was prompted by the recent availability of a significant amount of openly accessible measured VS30 values and the desire to investigate the trend of using proxy-based models to predict VS30 in the absence of measurements. Comparisons between measured and model-based values were performed. The measured data included 503 VS30 values collected from various projects for 482 seismographic station sites in California. Six proxy-based models—employing geologic mapping, topographic slope, and terrain classification—were also considered. Included was a new terrain class model based on the Yong et al. (2012) approach but recalibrated with updated measured VS30 values. Using the measured VS30 data as the metric for performance, the predictive capabilities of the six models were determined to be statistically indistinguishable. This study also found three models that tend to underpredict VS30 at lower velocities (NEHRP Site Classes D–E) and overpredict at higher velocities (Site Classes B–C).

  3. Computerized tomography attenuation values can be used to differentiate hydronephrosis from pyonephrosis.

    PubMed

    Yuruk, Emrah; Tuken, Murat; Sulejman, Suhejb; Colakerol, Aykut; Serefoglu, Ege Can; Sarica, Kemal; Muslumanoglu, Ahmet Yaser

    2017-03-01

    To determine the diagnostic value of computerized tomography (CT) in differentiating pyonephrosis from hydronephrosis on the basis of attenuation values (Hounsfield unit-HU). Data of the patients with grades 1-3 hydronephrosis on abdominopelvic CT, who underwent nephrostomy tube placement for decompression of the collecting system, were retrospectively analyzed. Patient demographics and CT findings were recorded along with the first access urine culture results. Three physicians calculated the surface areas and the attenuation values of the dilated collecting systems using the system software. Mean HU of pyonephrosis and hydronephrosis cases was compared. A total of 105 patients with the mean age of 47.7 ± 15.5 (range 20-80) were included. The interclass correlation coefficient of three physicians was 0.981 for HU measurement and 0.999 for calculation of collecting system surface area. Of the patients, 47 (44.8 %) had pyonephrosis. Mean surface areas of the collecting system were similar in patients with pyonephrosis and hydronephrosis (1481.13 ± 1562.94 vs. 1612.94 ± 2261.4 mm 2 , p = 0.735). Urine cultures were positive in all patients with pyonephrosis, whereas 12.7 % of hydronephrosis cases had bacterial in first access urine culture. The HU of the patients with pyonephrosis was significantly higher that that of patients with hydronephrosis (13.51 ± 13.29 vs. 4.67 ± 5.37, p = 0.0001). Having a HU of 9.21 or over diagnosed pyonephrosis accurately with 65.96 % sensitivity and 87.93 % specificity. Measuring attenuation values of the collecting system may be useful to differentiate pyonephrosis from hydronephrosis. Diagnosing pyonephrosis accurately may avoid septic complications.

  4. Diversifying natural resources value measurements: The Trinity River study

    USGS Publications Warehouse

    Taylor, J.G.; Douglas, A.J.

    1999-01-01

    An interdisciplinary team set out to establish the economic and social values of the Trinity River in northern California. This information was intended to support the Secretary of the Interior's decision on allocation of Trinity River flows. This team set out to measure the values of Trinity River flows, fishery resources, and recreation amenities in several different ways. A survey was mailed to users of the Trinity River. This single instrument included economic measures (willingness-to-pay and costs incurred in visiting) and social-psychological measures (importance, satisfaction, and water allocation preferences). A closely related survey measured several of these same values among west coast regional households. The results of these surveys were compiled, and the measured economic and social values were compared. We found that integrating economic and social value information provides a greater depth of understanding of the resource's value. In addition, this integration provides a more in-depth understanding through the quantitative and qualitative results that emerge.

  5. Can Value-Added Measures of Teacher Performance Be Trusted? Working Paper #18

    ERIC Educational Resources Information Center

    Guarino, Cassandra M.; Reckase, Mark D.; Woolridge, Jeffrey M.

    2012-01-01

    We investigate whether commonly used value-added estimation strategies can produce accurate estimates of teacher effects. We estimate teacher effects in simulated student achievement data sets that mimic plausible types of student grouping and teacher assignment scenarios. No one method accurately captures true teacher effects in all scenarios,…

  6. Can reliable values of Young's modulus be deduced from Fisher's (1971) spinning lens measurements?

    PubMed

    Burd, H J; Wilde, G S; Judge, S J

    2006-04-01

    The current textbook view of the causes of presbyopia rests very largely on a series of experiments reported by R.F. Fisher some three decades ago, and in particular on the values of lens Young's modulus inferred from the deformation caused by spinning excised lenses about their optical axis (Fisher 1971) We studied the extent to which inferred values of Young's modulus are influenced by assumptions inherent in the mathematical procedures used by Fisher to interpret the test and we investigated several alternative interpretation methods. The results suggest that modelling assumptions inherent in Fisher's original method may have led to systematic errors in the determination of the Young's modulus of the cortex and nucleus. Fisher's conclusion that the cortex is stiffer than the nucleus, particularly in middle age, may be an artefact associated with these systematic errors. Moreover, none of the models we explored are able to account for Fisher's claim that the removal of the capsule has only a modest effect on the deformations induced in the spinning lens.

  7. Weak values in continuous weak measurements of qubits

    NASA Astrophysics Data System (ADS)

    Qin, Lupei; Liang, Pengfei; Li, Xin-Qi

    2015-07-01

    For continuous weak measurements of qubits, we obtain exact expressions for weak values (WVs) from the postselection restricted average of measurement outputs, by using both the quantum-trajectory equation (QTE) and the quantum Bayesian approach. The former is applicable to short-time weak measurement, while the latter can relax the measurement strength to finite. We find that even in the "very" weak limit the result can be essentially different from the one originally proposed by Aharonov, Albert, and Vaidman (AAV), in the sense that our result incorporates nonperturbative correction which could be important when the AAV WV is large. Within the Bayesian framework, we obtain also elegant expressions for finite measurement strength and find that the amplifier's noise in quantum measurement has no effect on the WVs. In particular, we obtain very useful results for homodyne measurement in a circuit-QED system, which allows for measuring the real and imaginary parts of the AAV WV by simply tuning the phase of the local oscillator. This advantage can be exploited as an efficient state-tomography technique.

  8. The B(E2;4^+1->2^+1) / B(E2;2^+1->0^+1) Ratio in Even-Even Nuclei

    NASA Astrophysics Data System (ADS)

    Loelius, C.; Sharon, Y. Y.; Zamick, L.; G"Urdal, G.

    2009-10-01

    We considered 207 even-even nuclei throughout the chart of nuclides for which the NNDC Tables had data on the energies and lifetimes of the 2^+1 and 4^+1 states. Using these data we calculated for each nucleus the electric quadrupole transition strengths B(E2;4^+1->2^+1) and B(E2;2^+1->0^+1), as well as their ratio. The internal conversion coefficients were obtained by using the NNDC HSICC calculator. For each nucleus we plotted the B(E2) ratio against A, N, and Z. We found that for close to 90% of the nuclei considered the ratio had values between 0.5 and 2.5. Most of the outliers had magic numbers of protons or neutrons. Our ratio results were compared with the theoretical predictions for this ratio by different models--10/7 in the rotational model and 2 in the simplest vibrational model. In the rotational regions (for 150 < A < 180 and A > 220) the ratios were indeed close to 10/7. For the few nuclei thought to be vibrational the ratios were usually less than 2. Otherwise, we got a wide scatter of ratio values. Hence other models, including the NpNn scheme, must be considered in interpreting these results.

  9. Measurement of 13C chemical shift tensor principal values with a magic-angle turning experiment.

    PubMed

    Hu, J Z; Orendt, A M; Alderman, D W; Pugmire, R J; Ye, C; Grant, D M

    1994-08-01

    The magic-angle turning (MAT) experiment introduced by Gan is developed into a powerful and routine method for measuring the principal values of 13C chemical shift tensors in powdered solids. A large-volume MAT probe with stable rotation frequencies down to 22 Hz is described. A triple-echo MAT pulse sequence is introduced to improve the quality of the two-dimensional baseplane. It is shown that measurements of the principal values of chemical shift tensors in complex compounds can be enhanced by using either short contact times or dipolar dephasing pulse sequences to isolate the powder patterns from protonated or non-protonated carbons, respectively. A model compound, 1,2,3-trimethoxybenzene, is used to demonstrate these techniques, and the 13C principal values in 2,3-dimethylnaphthalene and Pocahontas coal are reported as typical examples.

  10. Microbial H2 cycling does not affect δ2H values of ground water

    USGS Publications Warehouse

    Landmeyer, J.E.; Chapelle, F.H.; Bradley, P.M.

    2000-01-01

    Stable hydrogen-isotope values of ground water (δ2H) and dissolved hydrogen concentrations (H(2(aq)) were quantified in a petroleum-hydrocarbon contaminated aquifer to determine whether the production/consumption of H2 by subsurface microorganisms affects ground water &delta2H values. The range of &delta2H observed in monitoring wells sampled (-27.8 ‰c to -15.5 ‰c) was best explained, however, by seasonal differences in recharge temperature as indicated using ground water δ18O values, rather than isotopic exchange reactions involving the microbial cycling of H2 during anaerobic petroleum-hydrocarbon biodegradation. The absence of a measurable hydrogen-isotope exchange between microbially cycled H2 and ground water reflects the fact that the amount of H2 available from the anaerobic decomposition of petroleum hydrocarbons is small relative to the amount of hydrogen present in water, even though milligram per liter concentrations of readily biodegradable contaminants are present at the study site. Additionally, isotopic fractionation calculations indicate that in order for H2 cycling processes to affect δ2H values of ground water, relatively high concentrations of H2 (>0.080 M) would have to be maintained, considerably higher than the 0.2 to 26 nM present at this site and characteristic of anaerobic conditions in general. These observations suggest that the conventional approach of using δ2H and δ18O values to determine recharge history is appropriate even for those ground water systems characterized by anaerobic conditions and extensive microbial H2 cycling.

  11. Attention! Can choices for low value food over high value food be trained?

    PubMed

    Zoltak, Michael J; Veling, Harm; Chen, Zhang; Holland, Rob W

    2018-05-01

    People choose high value food items over low value food items, because food choices are guided by the comparison of values placed upon choice alternatives. This value comparison process is also influenced by the amount of attention people allocate to different items. Recent research shows that choices for food items can be increased by training attention toward these items, with a paradigm named cued-approach training (CAT). However, previous work till now has only examined the influence of CAT on choices between two equally valued items. It has remained unclear whether CAT can increase choices for low value items when people choose between a low and high value food item. To address this question in the current study participants were cued to make rapid responses in CAT to certain low and high value items. Next, they made binary choices between low and high value items, where we systematically varied whether the low and high value items were cued or uncued. In two experiments, we found that participants overall preferred high over low value food items for real consumption. More important, their choices for low value items increased when only the low value item had been cued in CAT compared to when both low and high value items had not been cued. Exploratory analyses revealed that this effect was more pronounced for participants with a relatively small value difference between low and high value items. The present research thus suggests that CAT may be used to boost the choice and consumption of low value items via enhanced attention toward these items, as long as the value difference is not too large. Implications for facilitating choices for healthy food are discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. How the reference values for serum parathyroid hormone concentration are (or should be) established?

    PubMed

    Souberbielle, J-C; Brazier, F; Piketty, M-L; Cormier, C; Minisola, S; Cavalier, E

    2017-03-01

    Well-validated reference values are necessary for a correct interpretation of a serum PTH concentration. Establishing PTH reference values needs recruiting a large reference population. Exclusion criteria for this population can be defined as any situation possibly inducing an increase or a decrease in PTH concentration. As recommended in the recent guidelines on the diagnosis and management of asymptomatic primary hyperparathyroidism, PTH reference values should be established in vitamin D-replete subjects with a normal renal function with possible stratification according to various factors such as age, gender, menopausal status, body mass index, and race. A consensus about analytical/pre-analytical aspects of PTH measurement is also needed with special emphasis on the nature of the sample (plasma or serum), the time and the fasting/non-fasting status of the blood sample. Our opinion is that blood sample for PTH measurement should be obtained in the morning after an overnight fast. Furthermore, despite longer stability of the PTH molecule in EDTA plasma, we prefer serum as it allows to measure calcium, a prerequisite for a correct interpretation of a PTH concentration, on the same sample. Once a consensus is reached, we believe an important international multicentre work should be performed to recruit a very extensive reference population of apparently healthy vitamin D-replete subjects with a normal renal function in order to establish the PTH normative data. Due to the huge inter-method variability in PTH measurement, a sufficient quantity of blood sample should be obtained to allow measurement with as many PTH kits as possible.

  13. Anorectal physiology measurements are of no value in clinical practice. True or false?

    PubMed Central

    Carty, N. J.; Moran, B.; Johnson, C. D.

    1994-01-01

    This article examines whether there is any clinical value in anorectal physiology measurements. The function of the human rectum is poorly understood and the factors which affect function of the anal sphincters are complex. Several laboratories have reported results of anorectal physiology measurements, but there is extensive variation between normal values in different laboratories. It is argued that anorectal physiology measurements fail to meet the criteria of a useful clinical test: 1. It is not widely available to clinicians; 2. It is not possible to establish a reproducible normal range; 3. Abnormal measurements do not correlate with disease entities or explain symptoms; 4. The results are often unhelpful in diagnosis and management; 5. Clinical outcome after intervention does not correlate with alteration in the measurements obtained. On the other hand it can be argued that anorectal physiology measurements do provide information that assists in the management of conditions such as constipation, anismus, Hirschsprung's disease, faecal incontinence and tenesmus. Management based on biofeedback modification of physiological responses requires these techniques as part of the biofeedback system. There is evidence that this may be appropriate in anismus and solitary rectal ulcer syndrome. However, the assessment of these difficult conditions and the interpretation of the results are probably at present best confined to specialist units. PMID:8074392

  14. Value-based neurosurgery: measuring and reducing the cost of microvascular decompression surgery.

    PubMed

    McLaughlin, Nancy; Upadhyaya, Pooja; Buxey, Farzad; Martin, Neil A

    2014-09-01

    Care providers have put significant effort into optimizing patient safety and quality of care. Value, defined as meaningful outcomes achieved per dollar spent, is emerging as a promising framework to redesign health care. Scarce data exist regarding cost measurement and containment for episodes of neurosurgical care. The authors assessed how cost measurement and strategic containment could be used to optimize the value of delivered care after the implementation and maturation of quality improvement initiatives. A retrospective study of consecutive patients undergoing microvascular decompression was performed. Group 1 comprised patients treated prior to the implementation of quality improvement interventions, and Group 2 consisted of those treated after the implementation and maturation of quality improvement processes. A third group, Group 3, represented a contemporary group studied after the implementation of cost containment interventions targeting the three most expensive activities: pre-incision time in the operating room (OR) and total OR time, intraoperative neuromonitoring (IOM), and bed assignment (and overall length of stay [LOS]). The value of care was assessed for all three groups. Forty-four patients were included in the study. Average preparation time pre-incision decreased from 73 to 65 to 45 minutes in Groups 1, 2, and 3, respectively. The average total OR time and OR cost were 434 minutes and $8513 in Group 1; 348 minutes and $7592 in Group 2; and 407 minutes and $8333 in Group 3. The average cost for IOM, excluding electrode needles, was $1557, $1585, and $1263, respectively, in Groups 1, 2, and 3. Average total cost for bed assignment was $5747, $5198, and $4535, respectively, in Groups 1, 2, and 3. The average total LOS decreased from 3.16 days in Group 1 to 2.14 days in Group 3. Complete relief of or a significant decrease in preoperative symptomatology was achieved in 42 of the 44 patients, respectively. Overall, the average cost of a surgical

  15. Additional Value of CH4 Measurement in a Combined 13C/H2 Lactose Malabsorption Breath Test: A Retrospective Analysis

    PubMed Central

    Houben, Els; De Preter, Vicky; Billen, Jaak; Van Ranst, Marc; Verbeke, Kristin

    2015-01-01

    The lactose hydrogen breath test is a commonly used, non-invasive method for the detection of lactose malabsorption and is based on an abnormal increase in breath hydrogen (H2) excretion after an oral dose of lactose. We use a combined 13C/H2 lactose breath test that measures breath 13CO2 as a measure of lactose digestion in addition to H2 and that has a better sensitivity and specificity than the standard test. The present retrospective study evaluated the results of 1051 13C/H2 lactose breath tests to assess the impact on the diagnostic accuracy of measuring breath CH4 in addition to H2 and 13CO2. Based on the 13C/H2 breath test, 314 patients were diagnosed with lactase deficiency, 138 with lactose malabsorption or small bowel bacterial overgrowth (SIBO), and 599 with normal lactose digestion. Additional measurement of CH4 further improved the accuracy of the test as 16% subjects with normal lactose digestion and no H2-excretion were found to excrete CH4. These subjects should have been classified as subjects with lactose malabsorption or SIBO. In conclusion, measuring CH4-concentrations has an added value to the 13C/H2 breath test to identify methanogenic subjects with lactose malabsorption or SIBO. PMID:26371034

  16. Measurement of the infrared optical constants for spectral modeling: n and k values for (NH4)2SO4 via single-angle reflectance and ellipsometric methods

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blake, Thomas A.; Brauer, Carolyn S.; Kelly-Gorham, Molly Rose K.

    The optical constants n and k can be used to model infrared spectra, including refraction, absorption, reflectance, and emissivity, but obtaining reliable values for solid materials (pure or otherwise) presents a challenge: In the past, the best results for n and k have been obtained from bulk, homogeneous materials, free of defects. That is, materials where the Fresnel equations are operant since there is no light scattering. Since it is often not possible to obtain a pure macroscopic (crystalline) material, it may be possible to press the material into a (uniform, void-free) disk. We have recently been able to domore » this with ammonium sulfate powder and then measured the n & k values via two independent methods: 1) Ellipsometry - which measures the changes in amplitude and phase of light reflected from the material of interest as a function of wavelength and angle of incidence, and 2) Single angle specular reflectance with an FT spectrometer using a specular reflectance device within an FT instrument which measures the change in amplitude of light reflected from the material of interest as a function of wavelength and angle of incidence over a wide wavelength range. The quality of the derived n & k values was tested by generating the reflectance spectra of the pellet and comparing to the calculated to measured reflectance spectra of the pure material which has been previously published. The comparison to literature values showed good accuracy and good agreement, indicating promise to measure other materials by such methods.« less

  17. Measuring the value of nonwage employee benefits: building a model of the relation between benefit satisfaction and value.

    PubMed

    Weathington, Bart L; Jones, Allan P

    2006-11-01

    Researchers have commonly assumed benefits that employees view as more valuable have a greater influence on their attitudes and behaviors. Researchers have used 2 common methods to measure benefit value: attaching a monetary value to benefits and using self-reports of benefit importance. The present authors propose that the 2 approaches are conceptually distinct and have different implications. They use a social exchange perspective to justify this distinction and integrate both approaches and benefit satisfaction into a more comprehensive model of benefit perception. Results suggest that both measures have practical applications depending on the nature of the exchange relationship between the organization and employees. However, this relationship depends on the specific benefit and on employee satisfaction with that benefit. Some benefits lend themselves to a monetary estimate, whereas others lend themselves more to a nonmonetary valuation.

  18. Anthropometric measurements may be informative for nursing home-acquired pneumonia

    PubMed Central

    Yardimci, Bulent; Aksoy, Sevki Murat; Ozkaya, Ismail; Demir, Tarik; Tezcan, Gulsen; Kaptanoglu, Aysegul Yildirim

    2016-01-01

    Objective: To evaluate the relationship between anthropometric measurements and Nursing Home-Acquired Pneumonia (NHAP) risk. Methods: Consecutive patients of 65 years or elderly who were living in the Balikli Rum Hospital Nursing Homes were included in this prospective study. At the beginning of this study, the patients’ anthropometrics values were measured. The patients were followed for one year, and any incidences of pneumonia attacks were recorded. The relationship between the anthropometric measurements and pneumonia occurrences was analyzed. Results: There were 133 inmates at the initial assessments. Of 108 patients who were eligible for the study, 77 (72.2%) were female and 37 (27.8%) were male. The mean age of the group was 79.8±10.5. Patients were assigned to a group according to the presence of pneumonia during the one -year follow-up. There were 74 (55.6%) patients who had suffered from at least one attack of pneumonia during the follow-up period. The mean triceps skinfold was significantly thinner in the pneumonia group, and the mean handgrip measurements in both the dominant and non-dominant hands were significantly weaker in the pneumonia group. Furthermore, the frequency of Chronic Obstructive Pulmonary Diseases (COPD) was significantly higher in this group (p < 0.001). Conclusions: The risk of pneumonia was high in the elderly population who live in nursing homes. Simple anthropometric values may be predictive of the potential for Nursing Home-Acquired Pneumonia. PMID:27375716

  19. Reference values for Lactate Pro 2™ in fetal blood sampling during labor: a cross-sectional study.

    PubMed

    Birgisdottir, Brynhildur Tinna; Holzmann, Malin; Varli, Ingela Hulthén; Graner, Sofie; Saltvedt, Sissel; Nordström, Lennart

    2017-04-01

    Lactate Pro™ (LP1) is the only lactate meter evaluated for fetal scalp blood sampling (FBS) in intrapartum use. The reference values for this meter are: normal value <4.2 mmol/L, preacidemia 4.2-4.8 mmol/L, and acidemia >4.8 mmol/L. The production of this meter has been discontinued. An updated version, Lactate Pro 2TM (LP2), has been launched and is shown to be differently calibrated. The aims of the study were to retrieve a conversion equation to convert lactate values in FBS measured with LP2 to an estimated value if using LP1 and to define reference values for clinical management when using LP2. A cross-sectional study was conducted at a university hospital in Sweden. A total of 113 laboring women with fetal heart rate abnormalities on cardiotocography (CTG) had FBS carried out. Lactate concentration was measured bedside with both LP1 and LP2 from the same blood sample capillary. A linear regression model was constructed to retrieve a conversion equation to convert LP2 values to LP1 values. LP2 measured higher values than LP1 in all analyses. We found that 4.2 mmol/L with LP1 corresponded to 6.4 mmol/L with LP2. Likewise, 4.8 mmol/L with LP1 corresponded to 7.3 mmol/L with LP2. The correlation between the analyses was excellent (Spearman's rank correlation, r=0.97). We recommend the following guidelines when interpreting lactate concentration in FBS with LP2: <6.4 mmol/L to be interpreted as normal, 6.4-7.3 mmol/L as preacidemia indicating a follow-up FBS within 20-30 min, and >7.3 mmol/L as acidemia indicating intervention.

  20. B (e 2 ;21+→01+) value in 90Kr

    NASA Astrophysics Data System (ADS)

    Régis, J.-M.; Jolie, J.; Saed-Samii, N.; Warr, N.; Pfeiffer, M.; Blanc, A.; Jentschel, M.; Köster, U.; Mutti, P.; Soldner, T.; Simpson, G. S.; Drouet, F.; Vancraeyenest, A.; de France, G.; Clément, E.; Stezowski, O.; Ur, C. A.; Urban, W.; Regan, P. H.; Podolyák, Zs.; Larijani, C.; Townsley, C.; Carroll, R.; Wilson, E.; Fraile, L. M.; Mach, H.; Paziy, V.; Olaizola, B.; Vedia, V.; Bruce, A. M.; Roberts, O. J.; Smith, J. F.; Kröll, T.; Hartig, A.-L.; Ignatov, A.; Ilieva, S.; Thürauf, M.; Lalkovski, S.; Ivanova, D.; Kisyov, S.; Korten, W.; Salsac, M.-D.; Zielińska, M.; Mǎrginean, N.; Ghitǎ, D. G.; Licǎ, R.; Petrache, C. M.; Astier, A.; Leguillon, R.

    2014-12-01

    A smooth onset of collectivity in 88 ,92 ,94 ,96Kr has been determined from reported B (E 2 ;21+→01+) and E (21+) values. This is in contrast to the sudden onset in even-even Zr, Mo, and Sr isotopes. Our objective was to complete the systematics by determining the B (E 2 ;21+→01+) value in 90Kr, which was produced by cold-neutron-induced fission of 235U . The lifetime of the 21+ state in 90Kr was measured via the electronic γ -γ timing technique using the EXILL and FATIMA spectrometers. Based on the measured mean lifetime of τ = 15(10) ps, the B (E 2 ;21+→01+) value of 13 -5+26 W.u. in 90Kr is determined for the first time and the smooth onset of deformation in the even-even Kr isotopes beyond neutron number N =50 is confirmed.

  1. What Is the Value of Value-Based Purchasing?

    PubMed

    Tanenbaum, Sandra J

    2016-10-01

    Value-based purchasing (VBP) is a widely favored strategy for improving the US health care system. The meaning of value that predominates in VBP schemes is (1) conformance to selected process and/or outcome metrics, and sometimes (2) such conformance at the lowest possible cost. In other words, VBP schemes choose some number of "quality indicators" and financially incent providers to meet them (and not others). Process measures are usually based on clinical science that cannot determine the effects of a process on individual patients or patients with comorbidities, and do not necessarily measure effects that patients value; additionally, there is no provision for different patients valuing different things. Proximate outcome measures may or may not predict distal ones, and the more distal the outcome, the less reliably it can be attributed to health care. Outcome measures may be quite rudimentary, such as mortality rates, or highly contestable: survival or function after prostate surgery? When cost is an element of value-based purchasing, it is the cost to the value-based payer and not to other payers or patients' families. The greatest value of value-based purchasing may not be to patients or even payers, but to policy makers seeking a morally justifiable alternative to politically contested regulatory policies. Copyright © 2016 by Duke University Press.

  2. Reorientation-effect measurement of the <21+∥E2̂∥21+> matrix element in 10Be

    NASA Astrophysics Data System (ADS)

    Orce, J. N.; Drake, T. E.; Djongolov, M. K.; Navrátil, P.; Triambak, S.; Ball, G. C.; Al Falou, H.; Churchman, R.; Cross, D. S.; Finlay, P.; Forssén, C.; Garnsworthy, A. B.; Garrett, P. E.; Hackman, G.; Hayes, A. B.; Kshetri, R.; Lassen, J.; Leach, K. G.; Li, R.; Meissner, J.; Pearson, C. J.; Rand, E. T.; Sarazin, F.; Sjue, S. K. L.; Stoyer, M. A.; Sumithrarachchi, C. S.; Svensson, C. E.; Tardiff, E. R.; Teigelhoefer, A.; Williams, S. J.; Wong, J.; Wu, C. Y.

    2012-10-01

    The highly-efficient and segmented TIGRESS γ-ray spectrometer at TRIUMF has been used to perform a reorientation-effect Coulomb-excitation study of the 21+ state at 3.368 MeV in 10Be. This is the first Coulomb-excitation measurement that enables one to obtain information on diagonal matrix elements for such a high-lying first excited state from γ-ray data. With the availability of accurate lifetime data, a value of -0.110±0.087 eb is determined for the <21+∥E2̂∥21+> diagonal matrix element, which assuming the rotor model, leads to a negative spectroscopic quadrupole moment of QS(21+)=-0.083±0.066 eb. This result is in agreement with both no-core shell-model calculations performed in this work with the CD-Bonn 2000 two-nucleon potential and large shell-model spaces, and Green's function Monte Carlo predictions with two- plus three-nucleon potentials.

  3. Deodorants, value, and performance.

    PubMed

    Newcomer, L N

    1997-11-01

    For the health-care market, like the deodorant market, the message is clear: Add value or your product will not be competitive. For physicians of all specialties, the best way to add value is to measure and improve performance. Performance measurement is critical to improvement in health care. Without measurement, there can be no improvement in quality. Without improvement in quality, there is no added value. Oncologists can take at least two actions to add value for their health plans: (1) measure practice performance and demonstrate a quality improvement; and (2) become the personal-care physician for cancer patients.

  4. Partial discharge measurements on 110kV current transformers. Setting the control value. Case study

    NASA Astrophysics Data System (ADS)

    Dan, C.; Morar, R.

    2017-05-01

    The case study presents a series of partial discharge measurements, reflecting the state of insulation of 110kV CURRENT TRANSFORMERS located in Sibiu county substations. Measurements were performed based on electrical method, using MPD600: an acquisition and analysis toolkit for detecting, recording, and analyzing partial discharges. MPD600 consists of one acquisition unit, an optical interface and a computer with dedicated software. The system allows measurements of partial discharge on site, even in presence of strong electromagnetic interferences because it provides synchronous acquisition from all measurement points. Therefore, measurements, with the ability to be calibrated, do render: - a value subject to interpretation according to IEC 61869-1:2007 + IEC 61869-2:2012 + IEC 61869-3:2011 + IEC 61869-5:2011 and IEC 60270: 2000; - the possibility to determine the quantitative limit of PD (a certain control value) to which the equipment can be operated safely and repaired with minimal costs (relative to the high costs implied by eliminating the consequences of a failure) identified empirically (process in which the instrument transformer subjected to the tests was completely destroyed).

  5. The incremental value of self-reported mental health measures in predicting functional outcomes of veterans.

    PubMed

    Eisen, Susan V; Bottonari, Kathryn A; Glickman, Mark E; Spiro, Avron; Schultz, Mark R; Herz, Lawrence; Rosenheck, Robert; Rofman, Ethan S

    2011-04-01

    Research on patient-centered care supports use of patient/consumer self-report measures in monitoring health outcomes. This study examined the incremental value of self-report mental health measures relative to a clinician-rated measure in predicting functional outcomes among mental health service recipients. Participants (n = 446) completed the Behavior and Symptom Identification Scale, the Brief Symptom Inventory, and the Veterans/Rand Short Form-36 at enrollment in the study (T1) and 3 months later (T2). Global Assessment of Functioning (GAF) ratings, mental health service utilization, and psychiatric diagnoses were obtained from administrative data files. Controlling for demographic and clinical variables, results indicated that improvement based on the self-report measures significantly predicted one or more functional outcomes (i.e., decreased likelihood of post-enrollment psychiatric hospitalization and increased likelihood of paid employment), above and beyond the predictive value of the GAF. Inclusion of self-report measures may be a useful addition to performance measurement efforts.

  6. Hospitals Known for Nursing Excellence Perform Better on Value Based Purchasing Measures

    PubMed Central

    Lasater, Karen B.; Germack, Hayley D.; Small, Dylan S.; McHugh, Matthew D.

    2018-01-01

    It is well-established that hospitals recognized for good nursing care – Magnet hospitals – are associated with better patient outcomes. Less is known about how Magnet hospitals compare to non-Magnets on quality measures linked to Medicare reimbursement. The purpose of this study was to determine how Magnet hospitals perform compared to matched non-Magnet hospitals on Hospital Value Based Purchasing (VBP) measures. A cross-sectional analysis of three linked data sources was performed. The sample included 3,021 non-federal acute care hospitals participating in the VBP program (323 Magnets; 2,698 non-Magnets). Propensity score matching was used to match Magnet and non-Magnet hospitals with similar hospital characteristics. After matching, linear and logistic regression models were used to examine the relationship between Magnet status and VBP performance. After matching and adjusting for hospital characteristics, Magnet recognition predicted higher scores on Total Performance (Regression Coefficient [RC] = 1.66, p < 0.05), Clinical Processes (RC = 3.85; p < 0.01), and Patient Experience (RC = 6.33; p < 0.001). The relationships between Magnet recognition and the Outcome and Efficiency domains were not statistically significant. Magnet hospitals known for nursing excellence perform better on Hospital VBP measures. As healthcare systems adapt to evolving incentives that reward value, attention to nurses at the front lines may be central to ensuring high-value care for patients. PMID:28558604

  7. Reference value sensitivity of measures of unfair health inequality

    PubMed Central

    García-Gómez, Pilar; Schokkaert, Erik; Van Ourti, Tom

    2014-01-01

    Most politicians and ethical observers are not interested in pure health inequalities, as they want to distinguish between different causes of health differences. Measures of “unfair” inequality - direct unfairness and the fairness gap, but also the popular standardized concentration index - therefore neutralize the effects of what are considered to be “legitimate” causes of inequality. This neutralization is performed by putting a subset of the explanatory variables at reference values, e.g. their means. We analyze how the inequality ranking of different policies depends on the specific choice of reference values. We show with mortality data from the Netherlands that the problem is empirically relevant and we suggest a statistical method for fixing the reference values. PMID:24954998

  8. E/N effects on K0 values revealed by high precision measurements under low field conditions

    NASA Astrophysics Data System (ADS)

    Hauck, Brian C.; Siems, William F.; Harden, Charles S.; McHugh, Vincent M.; Hill, Herbert H.

    2016-07-01

    Ion mobility spectrometry (IMS) is used to detect chemical warfare agents, explosives, and narcotics. While IMS has a low rate of false positives, their occurrence causes the loss of time and money as the alarm is verified. Because numerous variables affect the reduced mobility (K0) of an ion, wide detection windows are required in order to ensure a low false negative response rate. Wide detection windows, however, reduce response selectivity, and interferents with similar K0 values may be mistaken for targeted compounds and trigger a false positive alarm. Detection windows could be narrowed if reference K0 values were accurately known for specific instrumental conditions. Unfortunately, there is a lack of confidence in the literature values due to discrepancies in the reported K0 values and their lack of reported error. This creates the need for the accurate control and measurement of each variable affecting ion mobility, as well as for a central accurate IMS database for reference and calibration. A new ion mobility spectrometer has been built that reduces the error of measurements affecting K0 by an order of magnitude less than ±0.2%. Precise measurements of ±0.002 cm2 V-1 s-1 or better have been produced and, as a result, an unexpected relationship between K0 and the electric field to number density ratio (E/N) has been discovered in which the K0 values of ions decreased as a function of E/N along a second degree polynomial trend line towards an apparent asymptote at approximately 4 Td.

  9. Can CO2 Turbulent Flux Be Measured by Lidar? A Preliminary Study

    NASA Technical Reports Server (NTRS)

    Gilbert, Fabien; Koch, Grady; Beyon, Jeffrey Y.; Hilton, Timothy W.; Davis, Kenneth J.; Andrews, Arlyn; Flamant, Pierre H.; Singh, Upendra N.

    2011-01-01

    The vertical profiling ofCO2 turbulent fluxes in the atmospheric boundary layer (ABL) is investigated using a coherent differential absorption lidar (CDIAL) operated nearby a tall tower in Wisconsin during June 2007. A CDIAL can perform simultaneous range-resolved CO2 DIAL and velocity measurements. The lidar eddy covariance technique is presented. The aims of the study are (i) an assessment of performance and current limitation of available CDIAL for CO2 turbulent fluxes and (ii) the derivation of instrument specifications to build a future CDIAL to perform accurate range-resolved CO2 fluxes. Experimental lidar CO2 mixing ratio and vertical velocity profiles are successfully compared with in situ sensors measurements. Time and space integral scales of turbulence in the ABL are addressed that result in limitation for time averaging and range accumulation. A first attempt to infer CO2 fluxes using an eddy covariance technique with currently available 2-mm CDIAL dataset is reported.

  10. Extracting joint weak values with local, single-particle measurements.

    PubMed

    Resch, K J; Steinberg, A M

    2004-04-02

    Weak measurement is a new technique which allows one to describe the evolution of postselected quantum systems. It appears to be useful for resolving a variety of thorny quantum paradoxes, particularly when used to study properties of pairs of particles. Unfortunately, such nonlocal or joint observables often prove difficult to measure directly in practice (for instance, in optics-a common testing ground for this technique-strong photon-photon interactions would be needed to implement an appropriate von Neumann interaction). Here we derive a general, experimentally feasible, method for extracting these joint weak values from correlations between single-particle observables.

  11. Valuing Informal Care Experience: Does Choice of Measure Matter?

    ERIC Educational Resources Information Center

    Mentzakis, Emmanouil; McNamee, Paul; Ryan, Mandy; Sutton, Matthew

    2012-01-01

    Well-being equations are often estimated to generate monetary values for non-marketed activities. In such studies, utility is often approximated by either life satisfaction or General Health Questionnaire scores. We estimate and compare monetary valuations of informal care for the first time in the UK employing both measures, using longitudinal…

  12. Measurement Invariance of Expectancy-Value Questionnaire in Physical Education

    ERIC Educational Resources Information Center

    Zhu, Xihe; Sun, Haichun; Chen, Ang; Ennis, Catherine

    2012-01-01

    Expectancy-Value Questionnaire (EVQ) measures student expectancy beliefs and task values of the domain content (Eccles & Wigfield, 1995). In this study the authors examine measurement invariance of EVQ in the domain of physical education between elementary and middle-school students. Participants included 811 students (3rd-5th grades) from 13…

  13. Measuring and predicting Delta(vap)H298 values of ionic liquids.

    PubMed

    Deyko, Alexey; Lovelock, Kevin R J; Corfield, Jo-Anne; Taylor, Alasdair W; Gooden, Peter N; Villar-Garcia, Ignacio J; Licence, Peter; Jones, Robert G; Krasovskiy, Vladimir G; Chernikova, Elena A; Kustov, Leonid M

    2009-10-14

    We report the enthalpies of vaporisation (measured using temperature programmed desorption by mass spectrometry) of twelve ionic liquids (ILs), covering four imidazolium, [C(m)C(n)Im]+, five pyrrolidinium, [C(n)C(m)Pyrr]+, two pyridinium, [C(n)Py]+, and a dication, [C3(C1Im)2]2+ based IL. These cations were paired with a range of anions: [BF4]-, [FeCl4]-, [N(CN)2]-, [PF3(C2F5)3]- ([FAP]-), [(CF3SO2)2N]- ([Tf2N]-) and [SCN]-. Using these results, plus those for a further eight imidazolium based ILs published earlier (which include the anions [CF3SO3]- ([TfO]-), [PF6]- and [EtSO4]-), we show that the enthalpies of vaporisation can be decomposed into three components. The first component is the Coulombic interaction between the ions, DeltaU(Cou,R), which is a function of the IL molar volume, V(m), and a parameter R(r) which quantifies the relative change in anion-cation distance on evaporation from the liquid phase to the ion pair in the gas phase. The second and third components are the van der Waals contributions from the anion, DeltaH(vdw,A), and the cation, DeltaH(vdw,C). We derive a universal value for R(r), and individual values of DeltaH(vdw,A) and DeltaH(vdw,C) for each of the anions and cations considered in this study. Given the molar volume, it is possible to estimate the enthalpies of vaporisation of ILs composed of any combination of the ions considered here; values for fourteen ILs which have not yet been studied experimentally are given.

  14. Singular value description of a digital radiographic detector: Theory and measurements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kyprianou, Iacovos S.; Badano, Aldo; Gallas, Brandon D.

    The H operator represents the deterministic performance of any imaging system. For a linear, digital imaging system, this system operator can be written in terms of a matrix, H, that describes the deterministic response of the system to a set of point objects. A singular value decomposition of this matrix results in a set of orthogonal functions (singular vectors) that form the system basis. A linear combination of these vectors completely describes the transfer of objects through the linear system, where the respective singular values associated with each singular vector describe the magnitude with which that contribution to the objectmore » is transferred through the system. This paper is focused on the measurement, analysis, and interpretation of the H matrix for digital x-ray detectors. A key ingredient in the measurement of the H matrix is the detector response to a single x ray (or infinitestimal x-ray beam). The authors have developed a method to estimate the 2D detector shift-variant, asymmetric ray response function (RRF) from multiple measured line response functions (LRFs) using a modified edge technique. The RRF measurements cover a range of x-ray incident angles from 0 deg. (equivalent location at the detector center) to 30 deg. (equivalent location at the detector edge) for a standard radiographic or cone-beam CT geometric setup. To demonstrate the method, three beam qualities were tested using the inherent, Lu/Er, and Yb beam filtration. The authors show that measures using the LRF, derived from an edge measurement, underestimate the system's performance when compared with the H matrix derived using the RRF. Furthermore, the authors show that edge measurements must be performed at multiple directions in order to capture rotational asymmetries of the RRF. The authors interpret the results of the H matrix SVD and provide correlations with the familiar MTF methodology. Discussion is made about the benefits of the H matrix technique with regards to

  15. [Gas Concentration Measurement Based on the Integral Value of Absorptance Spectrum].

    PubMed

    Liu, Hui-jun; Tao, Shao-hua; Yang, Bing-chu; Deng, Hong-gui

    2015-12-01

    The absorptance spectrum of a gas is the basis for the qualitative and quantitative analysis of the gas by the law of the Lambert-Beer. The integral value of the absorptance spectrum is an important parameter to describe the characteristics of the gas absorption. Based on the measured absorptance spectrum of a gas, we collected the required data from the database of HIT-RAN, and chose one of the spectral lines and calculated the integral value of the absorptance spectrum in the frequency domain, and then substituted the integral value into Lambert-Beer's law to obtain the concentration of the detected gas. By calculating the integral value of the absorptance spectrum we can avoid the more complicated calculation of the spectral line function and a series of standard gases for calibration, so the gas concentration measurement will be simpler and faster. We studied the changing trends of the integral values of the absorptance spectrums versus temperature. Since temperature variation would cause the corresponding variation in pressure, we studied the changing trends of the integral values of the absorptance spectrums versus both the pressure not changed with temperature and changed with the temperature variation. Based on the two cases, we found that the integral values of the absorptance spectrums both would firstly increase, then decrease, and finally stabilize with temperature increasing, but the ranges of specific changing trend were different in the two cases. In the experiments, we found that the relative errors of the integrated values of the absorptance spectrum were much higher than 1% and still increased with temperature when we only considered the change of temperature and completely ignored the pressure affected by the temperature variation, and the relative errors of the integrated values of the absorptance spectrum were almost constant at about only 1% when we considered that the pressure were affected by the temperature variation. As the integral value

  16. Measure-valued solutions to the complete Euler system revisited

    NASA Astrophysics Data System (ADS)

    Březina, Jan; Feireisl, Eduard

    2018-06-01

    We consider the complete Euler system describing the time evolution of a general inviscid compressible fluid. We introduce a new concept of measure-valued solution based on the total energy balance and entropy inequality for the physical entropy without any renormalization. This class of so-called dissipative measure-valued solutions is large enough to include the vanishing dissipation limits of the Navier-Stokes-Fourier system. Our main result states that any sequence of weak solutions to the Navier-Stokes-Fourier system with vanishing viscosity and heat conductivity coefficients generates a dissipative measure-valued solution of the Euler system under some physically grounded constitutive relations. Finally, we discuss the same asymptotic limit for the bi-velocity fluid model introduced by H.Brenner.

  17. Measurements of the nucleon structure function in the range 0.002 < x < 0.17 and 00.2 < Q2 < 8 GeV2 in deuterium, carbon and calcium

    NASA Astrophysics Data System (ADS)

    European Muon Collaboration; Arneodo, M.; Arvidson, A.; Aubert, J. J.; Badelek, B.; Beaufays, J.; Bee, C. P.; Benchouk, C.; Berghoff, G.; Bird, I. G.; Blum, D.; Böhm, E.; de Bouard, X.; Brasse, F. W.; Braun, H.; Broll, C.; Brown, S. C.; Brück, H.; Calén, H.; Chima, J. S.; Ciborowski, J.; Clifft, R.; Coignet, G.; Combley, F.; Coughlan, J.; d'Agostini, G.; Dahlgren, S.; Derado, I.; Dreyer, T.; Drees, J.; Düren, M.; Eckardt, V.; Edwards, A.; Edwards, M.; Ernst, T.; Eszes, G.; Favier, J.; Ferrero, M. I.; Figiel, J.; Flauger, W.; Foster, J.; Gabathuler, E.; Gajewski, J.; Gamet, R.; Geddes, N.; Grafström, P.; Gustafsson, L.; Haas, J.; Hagberg, E.; Hasert, F. J.; Hayman, P.; Heusse, P.; Jaffre, M.; Jacholkowska, A.; Janata, F.; Jancso, G.; Johnson, A. S.; Kabuss, E. M.; Kellner, G.; Krüger, A.; Krüger, J.; Kullander, S.; Landgraf, U.; Lanske, D.; Loken, J.; Long, K.; Maire, M.; Malecki, P.; Manz, A.; Maselli, S.; Mohr, W.; Montanet, F.; Montgomery, H. E.; Nagy, E.; Nassalski, J.; Norton, P. R.; Oakham, F. G.; Osborne, A. M.; Pascaud, C.; Pawlik, B.; Payre, P.; Peroni, C.; Peschel, H.; Pessard, H.; Pettingale, J.; Pietrzyk, B.; Poensgen, B.; Pötsch, M.; Renton, P.; Ribarics, P.; Rith, K.; Rondio, E.; Sandacz, A.; Scheer, M.; Schlagböhmer, A.; Schiemann, H.; Schmitz, N.; Schneegans, M.; Scholz, M.; Schouten, M.; Schröder, T.; Schultze, K.; Sloan, T.; Stier, H. E.; Studt, M.; Taylor, G. N.; Thenard, J. M.; Thompson, J. C.; de la Torre, A.; Toth, J.; Urban, L.; Urban, L.; Wallucks, W.; Whalley, M.; Wheeler, S.; Williams, W. S. C.; Wimpenny, S. J.; Windmolders, R.; Wolf, G.

    1990-03-01

    Small angle scattering of 280 GeV positive muons by deuterium, carbon and calcium has been measured at scattering angles down to 2 mrad. The nucleon structure function F2 extracted from deuterium does not show a significant x dependence in the measured range of Q2 and its Q2 dependence is linear in logQ2. For calcium, a depletion of F2 is observed at low x by 30% as compared with the values at x = 0.1 where F2(Ca) and F2 (D) are not significantly different. This depletion is attributed to shadowing. The carbon structure function exhibits a similar, but less pronounced, x dependence. Such behaviour is observed to be independent of Q2. The data are consistent with those obtained from other charged lepton experiments both at similar and higher values of x and Q2 and considerably extend the range of the measurements down to the low values of x to be measured in forthcoming experiments at HERA.

  18. Measuring Work Values of Public School Administrators.

    ERIC Educational Resources Information Center

    Hales, Loyde W.; Waggoner, Jacqueline

    This paper presents the results of research investigating (1) the reliability and validity of the Ohio Work Values Inventory (OWVI) when used with public school administrators; (2) the work values of public school administrators; (3) differences in work values of male and female administrators; and (4) differences in work values of individuals at…

  19. Student-Valued Measurable Teaching Behaviors of Award-Winning Pharmacy Preceptors.

    PubMed

    O'Sullivan, Teresa A; Lau, Carmen; Patel, Mitul; Mac, Chi; Krueger, Janelle; Danielson, Jennifer; Weber, Stanley S

    2015-12-25

    To identify specific preceptor teaching-coaching, role modeling, and facilitating behaviors valued by pharmacy students and to develop measures of those behaviors that can be used for an experiential education quality assurance program. Using a qualitative research approach, we conducted a thematic analysis of student comments about excellent preceptors to identify behaviors exhibited by those preceptors. Identified behaviors were sorted according to the preceptor's role as role model, teacher/coach, or learning facilitator; measurable descriptors for each behavior were then developed. Data analysis resulted in identification of 15 measurable behavior themes, the most frequent being: having an interest in student learning and success, making time for students, and displaying a positive preceptor attitude. Measureable descriptors were developed for 5 role-modeling behaviors, 6 teaching-coaching behaviors, and 4 facilitating behaviors. Preceptors may need to be evaluated in their separate roles as teacher-coach, role model, and learning facilitator. The developed measures in this report could be used in site quality evaluation.

  20. Reference values for physical performance measures in the aging working population.

    PubMed

    Cote, Mark P; Kenny, Anne; Dussetschleger, Jeffrey; Farr, Dana; Chaurasia, Ashok; Cherniack, Martin

    2014-02-01

    The aim of this study was to determine reference physical performance values in older aging workers. Cross-sectional physical performance measures were collected for 736 manufacturing workers to assess effects of work and nonwork factors on age-related changes in musculoskeletal function and health. Participants underwent surveys and physical testing that included bioelectrical impedance analysis, range-of-motion measures, exercise testing, and dynamic assessment. Physical characteristics, such as blood pressure and body fat percentage, were comparable to published values. Dynamic and range-of-motion measurements differed from published normative results. Women had age-related decreases in cervical extension and lateral rotation. Older men had better spinal flexion than expected. Predicted age-related decline in lower-extremity strength and shoulder strength in women was not seen. Men declined in handgrip, lower-extremity strength, and knee extension strength, but not trunk strength, across age groups. There was no appreciable decline in muscle fatigue at the trunk, shoulder, and knee with aging for either gender, except for the youngest age group of women. Normative values may underestimate physical performance in "healthy" older workers, thereby underappreciating declines in less healthy older workers. Work may be preservative of function for a large group of selected individuals. A "healthy worker effect" may be greater for musculoskeletal disease and function than for heart disease and mortality. Clinicians and researchers studying musculoskeletal function in older workers can use a more specific set of reference values.

  1. A reanalysis of radioisotope measurements of the $^9$Be$$(\\gamma,n)^8$$Be cross-section

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Robinson, Alan E.

    Themore » $^9$Be$$(\\gamma,n)^8$$Be reaction is enhanced by a near threshold $1/2^+$ state. Contradictions between existing measurements of this reaction cross-section affect calculations of astrophysical r-process yields, dark matter detector calibrations, and the theory of the nuclear structure of $^9$Be. Select well-documented radioisotope $^9$Be$$(\\gamma,n)$$ source yield measurements have been reanalyzed, providing a set of high-accuracy independently measured cross sections. A Breit-Wigner fit of these corrected measurements yields $$E_R=1738.8\\pm1.9$$ keV, $$\\Gamma_\\gamma=0.771\\pm0.021$$ eV, and $$\\Gamma_n=268\\pm15$$ keV for the $1/2^+$ state. A virtual $1/2^+$ state is excluded with 99.3\\% confidence.« less

  2. A reanalysis of radioisotope measurements of the $^9$Be$$(\\gamma,n)^8$$Be cross-section

    DOE PAGES

    Robinson, Alan E.

    2016-02-18

    Themore » $^9$Be$$(\\gamma,n)^8$$Be reaction is enhanced by a near threshold $1/2^+$ state. Contradictions between existing measurements of this reaction cross-section affect calculations of astrophysical r-process yields, dark matter detector calibrations, and the theory of the nuclear structure of $^9$Be. Select well-documented radioisotope $^9$Be$$(\\gamma,n)$$ source yield measurements have been reanalyzed, providing a set of high-accuracy independently measured cross sections. A Breit-Wigner fit of these corrected measurements yields $$E_R=1738.8\\pm1.9$$ keV, $$\\Gamma_\\gamma=0.771\\pm0.021$$ eV, and $$\\Gamma_n=268\\pm15$$ keV for the $1/2^+$ state. A virtual $1/2^+$ state is excluded with 99.3\\% confidence.« less

  3. 29 CFR 4044.72 - Form of annuity to be valued.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Form of annuity to be valued. 4044.72 Section 4044.72 Labor... annuity to be valued. (a) When both the participant and beneficiary are alive on the date of distribution, the form of annuity to be valued is— (1) For a participant or beneficiary already receiving a monthly...

  4. Implementing Value-Added Measures of School Effectiveness: Getting the Incentives Right.

    ERIC Educational Resources Information Center

    Ladd, Helen F.; Walsh, Randall P.

    2002-01-01

    Evaluates value-added approach to measuring school effectiveness in North and South Carolina. Finds that value-added approach favors high-achievement schools, with large percentage of students from high-SES backgrounds. Discusses statistical problems in measuring value added. Concludes teachers' and administrators' avoidance of low-achievement,…

  5. Examining the Perceived Value of Integration of Earned Value Management with Risk Management-Based Performance Measurement Baseline

    ERIC Educational Resources Information Center

    Shah, Akhtar H.

    2014-01-01

    Many projects fail despite the use of evidence-based project management practices such as Performance Measurement Baseline (PMB), Earned Value Management (EVM) and Risk Management (RM). Although previous researchers have found that integrated project management techniques could be more valuable than the same techniques used by themselves, these…

  6. Clustering of reads with alignment-free measures and quality values.

    PubMed

    Comin, Matteo; Leoni, Andrea; Schimd, Michele

    2015-01-01

    The data volume generated by Next-Generation Sequencing (NGS) technologies is growing at a pace that is now challenging the storage and data processing capacities of modern computer systems. In this context an important aspect is the reduction of data complexity by collapsing redundant reads in a single cluster to improve the run time, memory requirements, and quality of post-processing steps like assembly and error correction. Several alignment-free measures, based on k-mers counts, have been used to cluster reads. Quality scores produced by NGS platforms are fundamental for various analysis of NGS data like reads mapping and error detection. Moreover future-generation sequencing platforms will produce long reads but with a large number of erroneous bases (up to 15 %). In this scenario it will be fundamental to exploit quality value information within the alignment-free framework. To the best of our knowledge this is the first study that incorporates quality value information and k-mers counts, in the context of alignment-free measures, for the comparison of reads data. Based on this principles, in this paper we present a family of alignment-free measures called D (q) -type. A set of experiments on simulated and real reads data confirms that the new measures are superior to other classical alignment-free statistics, especially when erroneous reads are considered. Also results on de novo assembly and metagenomic reads classification show that the introduction of quality values improves over standard alignment-free measures. These statistics are implemented in a software called QCluster (http://www.dei.unipd.it/~ciompin/main/qcluster.html).

  7. Social values for ecosystem services (SolVES): Documentation and user manual, version 2.0

    USGS Publications Warehouse

    Sherrouse, Benson C.; Semmens, Darius J.

    2012-01-01

    In response to the need for incorporating quantified and spatially explicit measures of social values into ecosystem services assessments, the Rocky Mountain Geographic Science Center (RMGSC), in collaboration with Colorado State University, developed a geographic information system (GIS) application, Social Values for Ecosystem Services (SolVES). With version 2.0 (SolVES 2.0), RMGSC has improved and extended the functionality of SolVES, which was designed to assess, map, and quantify the perceived social values of ecosystem services. Social values such as aesthetics, biodiversity, and recreation can be evaluated for various stakeholder groups as distinguished by their attitudes and preferences regarding public uses, such as motorized recreation and logging. As with the previous version, SolVES 2.0 derives a quantitative, 10-point, social-values metric, the Value Index, from a combination of spatial and nonspatial responses to public attitude and preference surveys and calculates metrics characterizing the underlying environment, such as average distance to water and dominant landcover. Additionally, SolVES 2.0 integrates Maxent maximum entropy modeling software to generate more complete social value maps and to produce robust statistical models describing the relationship between the social values maps and explanatory environmental variables. The performance of these models can be evaluated for a primary study area, as well as for similar areas where primary survey data are not available but where social value mapping could potentially be completed using value-transfer methodology. SolVES 2.0 also introduces the flexibility for users to define their own social values and public uses, model any number and type of environmental variable, and modify the spatial resolution of analysis. With these enhancements, SolVES 2.0 provides an improved public domain tool for decisionmakers and researchers to evaluate the social values of ecosystem services and to facilitate

  8. CAN CONTINGENT VALUATION MEASURE PASSIVE USE VALUES

    EPA Science Inventory

    Contingent valuation (CV) is the only method currently available for practically measuring passive-use values. Because proposed laws may require that environmental regulations pass a benefit-cost test, CV has become central to the policy debate on environmental protection. Crit...

  9. Valuing vaccines using value of statistical life measures.

    PubMed

    Laxminarayan, Ramanan; Jamison, Dean T; Krupnick, Alan J; Norheim, Ole F

    2014-09-03

    Vaccines are effective tools to improve human health, but resources to pursue all vaccine-related investments are lacking. Benefit-cost and cost-effectiveness analysis are the two major methodological approaches used to assess the impact, efficiency, and distributional consequences of disease interventions, including those related to vaccinations. Childhood vaccinations can have important non-health consequences for productivity and economic well-being through multiple channels, including school attendance, physical growth, and cognitive ability. Benefit-cost analysis would capture such non-health benefits; cost-effectiveness analysis does not. Standard cost-effectiveness analysis may grossly underestimate the benefits of vaccines. A specific willingness-to-pay measure is based on the notion of the value of a statistical life (VSL), derived from trade-offs people are willing to make between fatality risk and wealth. Such methods have been used widely in the environmental and health literature to capture the broader economic benefits of improving health, but reservations remain about their acceptability. These reservations remain mainly because the methods may reflect ability to pay, and hence be discriminatory against the poor. However, willingness-to-pay methods can be made sensitive to income distribution by using appropriate income-sensitive distributional weights. Here, we describe the pros and cons of these methods and how they compare against standard cost-effectiveness analysis using pure health metrics, such as quality-adjusted life years (QALYs) and disability-adjusted life years (DALYs), in the context of vaccine priorities. We conclude that if appropriately used, willingness-to-pay methods will not discriminate against the poor, and they can capture important non-health benefits such as financial risk protection, productivity gains, and economic wellbeing. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. The VALS: A new tool to measure people's general valued attributes of landscapes.

    PubMed

    Kendal, Dave; Ford, Rebecca M; Anderson, Nerida M; Farrar, Alison

    2015-11-01

    Research on values for natural areas has largely focussed on theoretical concerns such as distinguishing different kinds of values held by people. However practice, policymaking, planning and management is typically focused on more tangible valued attributes of the landscape such as biodiversity and recreation infrastructure that can be manipulated by management actions. There is a need for valid psychometric measures of such values that are suited to informing land management policies. A Valued Attributes of Landscape Scale (VALS) was developed, derived from a document analysis of values expressed in public land policy documents. The validity of the VALS was tested in an online survey comparing values across one of three randomly presented landscape contexts in Victoria, Australia: all publicly managed natural land, coastal areas, and large urban parks. A purposive snowball sample was used to recruit participants with a range of views and professional experience with land management, including members of the urban public. Factor analysis of responses (n = 646) separated concepts relating to natural attributes, social functions, the experience of being in natural areas, cultural attributes and productive uses. Relative importance of valued attribute factors was similar across all landscape contexts, although there were small but significant differences in the way people valued social functions (higher in urban parks) and productive uses (lower in urban parks). We conclude that the concept of valued attributes is useful for linking theoretical understandings of people's environmental values to the way values are considered by land managers, and that these attributes can be measured using the VALS instrument to produce data that should be useful for the policy and planning of natural resources. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Reverse engineering gene regulatory networks from measurement with missing values.

    PubMed

    Ogundijo, Oyetunji E; Elmas, Abdulkadir; Wang, Xiaodong

    2016-12-01

    Gene expression time series data are usually in the form of high-dimensional arrays. Unfortunately, the data may sometimes contain missing values: for either the expression values of some genes at some time points or the entire expression values of a single time point or some sets of consecutive time points. This significantly affects the performance of many algorithms for gene expression analysis that take as an input, the complete matrix of gene expression measurement. For instance, previous works have shown that gene regulatory interactions can be estimated from the complete matrix of gene expression measurement. Yet, till date, few algorithms have been proposed for the inference of gene regulatory network from gene expression data with missing values. We describe a nonlinear dynamic stochastic model for the evolution of gene expression. The model captures the structural, dynamical, and the nonlinear natures of the underlying biomolecular systems. We present point-based Gaussian approximation (PBGA) filters for joint state and parameter estimation of the system with one-step or two-step missing measurements . The PBGA filters use Gaussian approximation and various quadrature rules, such as the unscented transform (UT), the third-degree cubature rule and the central difference rule for computing the related posteriors. The proposed algorithm is evaluated with satisfying results for synthetic networks, in silico networks released as a part of the DREAM project, and the real biological network, the in vivo reverse engineering and modeling assessment (IRMA) network of yeast Saccharomyces cerevisiae . PBGA filters are proposed to elucidate the underlying gene regulatory network (GRN) from time series gene expression data that contain missing values. In our state-space model, we proposed a measurement model that incorporates the effect of the missing data points into the sequential algorithm. This approach produces a better inference of the model parameters and hence

  12. Negative measurement sensitivity values of planar capacitive imaging probes

    NASA Astrophysics Data System (ADS)

    Yin, Xiaokang; Chen, Guoming; Li, Wei; Hutchins, David

    2014-02-01

    The measurement sensitivity distribution of planar capacitive imaging (CI) probes describes how effectively each region in the sensing area is contributing to the measured charge signal on the sensing electrode. It can be used to determine the imaging ability of a CI probe. It is found in previous work that, there are regions in the sensing area where the change of the charge output and the change of targeting physical parameter are of opposite trends. This opposite correlation implies that the measurement sensitivity values in such regions are negative. In this work, the cause of negative sensitivity is discussed. Experiments are also designed and performed so as to verify the existence of negative sensitivity and study the factors that may affect the negative sensitivity distributions.

  13. Personal values, subjective well-being and destination-loyalty intention of international students.

    PubMed

    Jamaludin, N L; Sam, D L; Sandal, G M; Adam, A A

    2016-01-01

    What are the factors that predict international students' destination-loyalty intention? This is the main question this paper addresses, using an online survey among 396 (short-term, N = 182) and (long-term, N = 214) international students at a Norwegian university. Structural equation model-AMOS was conducted to examine relationships among personal values, subjective well-being and destination-loyalty intentions. The results showed that: (1) universalism was positively related to subjective well-being for short-term students; and (2) subjective well-being was positively related to destination-loyalty intention for all groups. We found that relatively stable and happy individuals might be important for ensuring destination-loyalty intentions. Results also indicated that personal values that emphasize justice and equity are also important for short-term international students' well-being.

  14. Can Virtue Be Measured?

    ERIC Educational Resources Information Center

    Curren, Randall; Kotzee, Ben

    2014-01-01

    This article explores some general considerations bearing on the question of whether virtue can be measured. What is moral virtue? What are measurement and evaluation, and what do they presuppose about the nature of what is measured or evaluated? What are the prospective contexts of, and purposes for, measuring or evaluating virtue, and how would…

  15. Can Teachers Be Evaluated by Their Students' Test Scores? Should They Be? The Use of Value-Added Measures of Teacher Effectiveness in Policy and Practice. Education Policy for Action Series

    ERIC Educational Resources Information Center

    Corcoran, Sean P.

    2010-01-01

    Value-added measures of teacher effectiveness are the centerpiece of a national movement to evaluate, promote, compensate, and dismiss teachers based in part on their students' test results. Federal, state, and local policy-makers have adopted these methods en masse in recent years in an attempt to objectively quantify teaching effectiveness and…

  16. Abundances of isotopologues and calibration of CO2 greenhouse gas measurements

    NASA Astrophysics Data System (ADS)

    Tans, Pieter P.; Crotwell, Andrew M.; Thoning, Kirk W.

    2017-07-01

    We have developed a method to calculate the fractional distribution of CO2 across all of its component isotopologues based on measured δ13C and δ18O values. The fractional distribution can be used with known total CO2 to calculate the amount of substance fraction (mole fraction) of each component isotopologue in air individually. The technique is applicable to any molecule where isotopologue-specific values are desired. We used it with a new CO2 calibration system to account for isotopic differences among the primary CO2 standards that define the WMO X2007 CO2-in-air calibration scale and between the primary standards and standards in subsequent levels of the calibration hierarchy. The new calibration system uses multiple laser spectroscopic techniques to measure mole fractions of the three major CO2 isotopologues (16O12C16O, 16O13C16O, and 16O12C18O) individually. The three measured values are then combined into total CO2 (accounting for the rare unmeasured isotopologues), δ13C, and δ18O values. The new calibration system significantly improves our ability to transfer the WMO CO2 calibration scale with low uncertainty through our role as the World Meteorological Organization Global Atmosphere Watch Central Calibration Laboratory for CO2. Our current estimates for reproducibility of the new calibration system are ±0.01 µmol mol-1 CO2, ±0.2 ‰ δ13C, and ±0.2 ‰ δ18O, all at 68 % confidence interval (CI).

  17. 10Be measured in a GRIP snow pit and modeled using the ECHAM5-HAM general circulation model

    NASA Astrophysics Data System (ADS)

    Heikkilä, U.; Beer, J.; Jouzel, J.; Feichter, J.; Kubik, P.

    2008-03-01

    10Be measured in a Greenland Ice Core Project (GRIP) snow pit (1986-1990) with a seasonal resolution is compared with the ECHAM5-HAM GCM run. The mean modeled 10Be concentration in ice (1.0.104 atoms/g) agrees well with the measured value (1.2.104 atoms/g). The measured 10Be deposition flux (88 atoms/m2/s) also agrees well with the modeled flux (69 atoms/m2/s) and the measured precipitation rate (0.67 mm/day) agrees with the modeled rate (0.61 mm/day). The mean surface temperature of -31°C estimated from δ 18O is lower than the temperature measured at a near-by weather station (-29°C) and the modeled temperature (-26°C). During the 5-year period the concentrations and deposition fluxes, both measured and modeled, show a decreasing trend consistent with the increase in the solar activity. The variability of the measured and modeled concentrations and deposition fluxes is very similar suggesting that the variability is linked to a variability in production rather than the local meteorology.

  18. The value of routine blood pressure measurement in children presenting to the emergency department with nonurgent problems.

    PubMed

    Stewart, Jessica N; McGillivray, David; Sussman, John; Foster, Bethany

    2008-10-01

    Blood pressure (BP) is measured at triage in most emergency departments (EDs). We aimed to determine the value of triage BP in diagnosing hypotension and true hypertension in children age > or =3 years presenting with nonurgent problems. In this prospective study, eligible children underwent automated BP measurement at triage. If BP was elevated, then the measurement was repeated manually. Children with a high manual BP were followed. True hypertension was defined as a manual BP >95th percentile for sex, age, and height measured on 3 occasions. Automated triage BP was measured in 549 children (53.4% male; mean age, 9.4 +/- 4.3 years) and was found to be elevated in 144 of them (26%). No child was hypotensive. Among the 495 patients with complete follow-up, the specificity and positive predictive value (PPV) of elevated triage BP in diagnosing true hypertension were 81.8% and 0%, respectively. A sensitivity analysis including those with incomplete follow-up, in which the population prevalence of true hypertension was assumed to be 1% to 2%, resulted in a specificity of 74.5% to 75.3% and a PPV of 3.8% to 7.5%. The yield of measuring BP at triage in children with nonurgent problems appears to be extremely low.

  19. What Value "Value Added"?

    ERIC Educational Resources Information Center

    Richards, Andrew

    2015-01-01

    Two quantitative measures of school performance are currently used, the average points score (APS) at Key Stage 2 and value-added (VA), which measures the rate of academic improvement between Key Stage 1 and 2. These figures are used by parents and the Office for Standards in Education to make judgements and comparisons. However, simple…

  20. How to Use Value-Added Measures Right

    ERIC Educational Resources Information Center

    Di Carlo, Matthew

    2012-01-01

    Value-added models are a specific type of "growth model," a diverse group of statistical techniques to isolate a teacher's impact on his or her students' testing progress while controlling for other measurable factors, such as student and school characteristics, that are outside that teacher's control. Opponents, including many teachers, argue…

  1. Influence of temperature on measurements of the CO2 compensation point: differences between the Laisk and O2-exchange methods.

    PubMed

    Walker, Berkley J; Cousins, Asaph B

    2013-04-01

    The CO2 compensation point in the absence of day respiration (Γ*) is a key parameter for modelling leaf CO2 exchange. Γ* links the kinetics of ribulose-1,5-bisphosphate carboxylase-oxygenase (Rubisco) with the stoichiometry of CO2 released per Rubisco oxygenation from photorespiration (α), two essential components of biochemical models of photosynthesis. There are two main gas-exchange methods for measuring Γ*: (i) the Laisk method, which requires estimates of mesophyll conductance to CO2 (g m) and (ii) measurements of O2 isotope exchange, which assume constant values of α and a fixed stoichiometry between O2 uptake and Rubisco oxygenation. In this study, the temperature response of Γ* measured using the Laisk and O2-exchange methods was compared under ambient (25 °C) and elevated (35 °C) temperatures to determine whether both methods yielded similar results. Previously published temperature responses of Γ* estimated with the Laisk and O2-exchange methods in Nicotiana tabacum demonstrated that the Laisk-derived model of Γ* was more sensitive to temperature compared with the O2-exchange model. Measurements in Arabidopsis thaliana indicated that the Laisk and O2-exchange methods produced similar Γ* at 25 °C; however, Γ* values from O2 exchange were lower at 35 °C compared with the Laisk method. Compared with a photorespiratory mutant (pmdh1pmdh2hpr) with increased α, wild-type (WT) plants had lower Laisk values of Γ* at 25 °C but were not significantly different at 35 °C. These differences between Laisk and O2 exchange values of Γ* at 35 °C could be explained by temperature sensitivity of α in WT and/or errors in the assumptions of O2 exchange. The differences between Γ* measured using the Laisk and O2-exchange method with temperature demonstrate that assumptions used to measure Γ*, and possibly the species-specific validity of these assumptions, need to be considered when modelling the temperature response of photosynthesis.

  2. Can shallow-layer measurements at a single location be used to predict deep soil water storage at the slope scale?

    NASA Astrophysics Data System (ADS)

    Gao, Lei; Lv, Yujuan; Wang, Dongdong; Tahir, Muhammad; Peng, Xinhua

    2015-12-01

    Knowing the amount of soil water storage (SWS) in agricultural soil profiles is important for understanding physical, chemical, and biological soil processes. However, measuring the SWS in deep soil layers is more expensive and time consuming than in shallower layers. Whether deep SWS can be predicted from shallow-layer measurements through temporal stability analysis (TSA) remains unclear. To address this issue, the soil water content was measured at depths of 0-1.6 m (0.2-m depth intervals) at 79 locations along an agricultural slope on 28 occasions between July 2013 and October 2014. SWSs values were then calculated for the 0-0.4, 0.4-0.8, 0.8-1.2, 1.2-1.6, and 0-1.6 m soil layers. The SWS exhibited strong temporal stability, with mean Spearman's ranking coefficients (rs) of 0.83, 0.92, 0.83, and 0.79 in the 0-0.4, 0.4-0.8, 0.8-1.2, and 1.2-1.6 m soil layers, respectively. As expected, the most temporally stable location (MTSL1) accurately predicted the average SWS of the corresponding soil layer, and the values of absolute bias relative to mean (ARB) were lower than 3% for all of the investigated soil layers. Using TSA, deep-layer SWS information could be predicted using a single-location measurement in the 0-0.4 m soil layer. The mean ARB values between the observed and predicted mean SWS values were 2.9%, 4.3%, 3.9%, and 2.7% in the 0.4-0.8, 0.8-1.2, 1.2-1.6, and 0-1.6 m soil layers, respectively. The prediction accuracy of the spatial distribution generally decreased with increasing depth, with linear determination coefficients (R2) of 0.93, 0.79, 0.72, and 0.84 for the four soil layers, respectively. The proposed method could further expand the application of the temporal stability technique in the estimation of SWS.

  3. Water vapor δ(2) H, δ(18) O and δ(17) O measurements using an off-axis integrated cavity output spectrometer - sensitivity to water vapor concentration, delta value and averaging-time.

    PubMed

    Tian, Chao; Wang, Lixin; Novick, Kimberly A

    2016-10-15

    High-precision analysis of atmospheric water vapor isotope compositions, especially δ(17) O values, can be used to improve our understanding of multiple hydrological and meteorological processes (e.g., differentiate equilibrium or kinetic fractionation). This study focused on assessing, for the first time, how the accuracy and precision of vapor δ(17) O laser spectroscopy measurements depend on vapor concentration, delta range, and averaging-time. A Triple Water Vapor Isotope Analyzer (T-WVIA) was used to evaluate the accuracy and precision of δ(2) H, δ(18) O and δ(17) O measurements. The sensitivity of accuracy and precision to water vapor concentration was evaluated using two international standards (GISP and SLAP2). The sensitivity of precision to delta value was evaluated using four working standards spanning a large delta range. The sensitivity of precision to averaging-time was assessed by measuring one standard continuously for 24 hours. Overall, the accuracy and precision of the δ(2) H, δ(18) O and δ(17) O measurements were high. Across all vapor concentrations, the accuracy of δ(2) H, δ(18) O and δ(17) O observations ranged from 0.10‰ to 1.84‰, 0.08‰ to 0.86‰ and 0.06‰ to 0.62‰, respectively, and the precision ranged from 0.099‰ to 0.430‰, 0.009‰ to 0.080‰ and 0.022‰ to 0.054‰, respectively. The accuracy and precision of all isotope measurements were sensitive to concentration, with the higher accuracy and precision generally observed under moderate vapor concentrations (i.e., 10000-15000 ppm) for all isotopes. The precision was also sensitive to the range of delta values, although the effect was not as large compared with the sensitivity to concentration. The precision was much less sensitive to averaging-time than the concentration and delta range effects. The accuracy and precision performance of the T-WVIA depend on concentration but depend less on the delta value and averaging-time. The instrument can

  4. New reference values for the Alberta Infant Motor Scale need to be established.

    PubMed

    Fleuren, K M W; Smit, L S; Stijnen, Th; Hartman, A

    2007-03-01

    The Alberta Infant Motor Scale (AIMS) is an infant developmental test, which can be used to evaluate motor performance from birth to independent walking. Between 1990 and 1992 Piper and Darrah determined reference values in a cohort in Canada. To our knowledge no study has been carried out to determine whether the Canadian data are representative for other countries. In the present study we aimed to establish whether the AIMS test needs new reference values for Dutch children. Motor performance of 100 Dutch children, aged 0-12 months, was measured using the AIMS test. The mean percentile score of the Dutch children was 28.8 (+/-22.9, range 1-85). The percentile scores of the group were significantly lower than scores of the Canadian norm population (p < 0.001), whereby 75% of the Dutch children scored below the 50th percentile. These lower scores were not be explained by sex, racial differences or congenital disorders and were seen in all age groups. We conclude that new reference values on the AIMS test for the age group of 0-12 months need to be established for Dutch children. It is recommended that the need for new normative data is also determined in all other European countries.

  5. Measuring energy efficiency in economics: Shadow value approach

    NASA Astrophysics Data System (ADS)

    Khademvatani, Asgar

    contributed to energy efficiency convergence analysis employing the delta-convergence and unconditional & conditional beta-convergence concepts, investigating economic energy efficiency differences across the four US sectors using panel data models. The results show that, in terms of technical and allocative energy efficiency, the energy-intensive sectors, SCG and textile mill products, tend to catch the energy extensive sectors, the Com and furniture & fixtures, being conditional on sector-specific characteristics. Conditional convergence results indicate that technology, capital and energy are crucial factors in determining energy efficiency differences across the US sectors, implying that environmental or energy policies, and technological changes should be industry specific across the US sectors. The main finding is that the marginal value measure conveys information on both technical and allocative energy efficiency and accounts for all costs and benefits of energy consumption including environmental and externality costs.

  6. Measuring the value of groundwater and other forms of natural capital.

    PubMed

    Fenichel, Eli P; Abbott, Joshua K; Bayham, Jude; Boone, Whitney; Haacker, Erin M K; Pfeiffer, Lisa

    2016-03-01

    Valuing natural capital is fundamental to measuring sustainability. The United Nations Environment Programme, World Bank, and other agencies have called for inclusion of the value of natural capital in sustainability metrics, such as inclusive wealth. Much has been written about the importance of natural capital, but consistent, rigorous valuation approaches compatible with the pricing of traditional forms of capital have remained elusive. We present a guiding quantitative framework enabling natural capital valuation that is fully consistent with capital theory, accounts for biophysical and economic feedbacks, and can guide interdisciplinary efforts to measure sustainability. We illustrate this framework with an application to groundwater in the Kansas High Plains Aquifer, a rapidly depleting asset supporting significant food production. We develop a 10-y time series (1996-2005) of natural capital asset prices that accounts for technological, institutional, and physical changes. Kansas lost approximately $110 million per year (2005 US dollars) of capital value through groundwater withdrawal and changes in aquifer management during the decade spanning 1996-2005. This annual loss in wealth is approximately equal to the state's 2005 budget surplus, and is substantially more than investments in schools over this period. Furthermore, real investment in agricultural capital also declined over this period. Although Kansas' depletion of water wealth is substantial, it may be tractably managed through careful groundwater management and compensating investments in other natural and traditional assets. Measurement of natural capital value is required to inform management and ongoing investments in natural assets.

  7. Interexaminer reliability in clinical measurement of L*C*h* values of anterior teeth using a spectrophotometer.

    PubMed

    Hassel, Alexander J; Grossmann, Anne-christiane; Schmitter, Marc; Balke, Zibandeh; Buzello, Anja M

    2007-01-01

    The objective of this study was to investigate interexaminer reliability in the clinical measurement of the L*C*h* (lightness/value, chroma, hue) values of anterior teeth using a spectrophotometer (Vita Easyshade). The basic color of the maxillary right central incisors and canines of 23 subjects was spectrophotometrically determined by 4 clinicians and an experienced user (development manager) of the spectrophotometer. Also, to analyze the effect of different training with the instrument on interexaminer reliability, 2 of the clinicians were instructed in the use of the spectrophotometer by the experienced examiner, whereas the others instructed themselves by studying the operating manual. Agreement between all examiners was acceptable to excellent (intraclass coefficient > 0.4). The mean value of the measured differences for the central incisors of all subjects for L* values was 5 (for C* = 3.8, h* = 2.7 degrees) and for canines, the mean L* was 4.5 (C* = 3, h* = 1.6 degrees). Results from comparison of the 2 different training methods were inconsistent. Agreement with the experienced examiner ranged from not acceptable (C* values for incisors of self-instructed examiners) to excellent. The distribution of the measurements of 1 subject could lead to deviations in color, probably with clinical impact. For canines, the measurements were at least equally reproducible (in some cases significantly more reproducible) compared to central incisors. Because of the small number of examiners and the inconsistent results, it was not possible to reach a definite conclusion about the effect of different training methods on interexaminer reliability.

  8. Automated simultaneous measurement of the δ(13) C and δ(2) H values of methane and the δ(13) C and δ(18) O values of carbon dioxide in flask air samples using a new multi cryo-trap/gas chromatography/isotope ratio mass spectrometry system.

    PubMed

    Brand, Willi A; Rothe, Michael; Sperlich, Peter; Strube, Martin; Wendeberg, Magnus

    2016-07-15

    The isotopic composition of greenhouse gases helps to constrain global budgets and to study sink and source processes. We present a new system for high-precision stable isotope measurements of carbon, hydrogen and oxygen in atmospheric methane and carbon dioxide. The design is intended for analyzing flask air samples from existing sampling programs without the need for extra sample air for methane analysis. CO2 and CH4 isotopes are measured simultaneously using two isotope ratio mass spectrometers, one for the analysis of δ(13) C and δ(18) O values and the second one for δ(2) H values. The inlet carousel delivers air from 16 sample positions (glass flasks 1-5 L and high-pressure cylinders). Three 10-port valves take aliquots from the sample stream. CH4 from 100-mL air aliquots is preconcentrated in 0.8-mL sample loops using a new cryo-trap system. A precisely calibrated working reference air is used in parallel with the sample according to the Principle of Identical Treatment. It takes about 36 hours for a fully calibrated analysis of a complete carousel including extractions of four working reference and one quality control reference air. Long-term precision values, as obtained from the quality control reference gas since 2012, account for 0.04 ‰ (δ(13) C values of CO2 ), 0.07 ‰ (δ(18) O values of CO2 ), 0.11 ‰ (δ(13) C values of CH4 ) and 1.0 ‰ (δ(2) H values of CH4 ). Within a single day, the system exhibits a typical methane δ(13) C standard deviation (1σ) of 0.06 ‰ for 10 repeated measurements. The system has been in routine operation at the MPI-BGC since 2012. Consistency of the data and compatibility with results from other laboratories at a high precision level are of utmost importance. A high sample throughput and reliability of operation are important achievements of the presented system to cope with the large number of air samples to be analyzed. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  9. Measuring the value of accurate link prediction for network seeding.

    PubMed

    Wei, Yijin; Spencer, Gwen

    2017-01-01

    The influence-maximization literature seeks small sets of individuals whose structural placement in the social network can drive large cascades of behavior. Optimization efforts to find the best seed set often assume perfect knowledge of the network topology. Unfortunately, social network links are rarely known in an exact way. When do seeding strategies based on less-than-accurate link prediction provide valuable insight? We introduce optimized-against-a-sample ([Formula: see text]) performance to measure the value of optimizing seeding based on a noisy observation of a network. Our computational study investigates [Formula: see text] under several threshold-spread models in synthetic and real-world networks. Our focus is on measuring the value of imprecise link information. The level of investment in link prediction that is strategic appears to depend closely on spread model: in some parameter ranges investments in improving link prediction can pay substantial premiums in cascade size. For other ranges, such investments would be wasted. Several trends were remarkably consistent across topologies.

  10. Strength Measurements in Acute Hamstring Injuries: Intertester Reliability and Prognostic Value of Handheld Dynamometry.

    PubMed

    Reurink, Gustaaf; Goudswaard, Gert Jan; Moen, Maarten H; Tol, Johannes L; Verhaar, Jan A N; Weir, Adam

    2016-08-01

    Study Design Cohort study, repeated measures. Background Although hamstring strength measurements are used for assessing prognosis and monitoring recovery after hamstring injury, their actual clinical relevance has not been established. Handheld dynamometry (HHD) is a commonly used method of measuring muscle strength. The reliability of HHD has not been determined in athletes with acute hamstring injuries. Objectives To determine the intertester reliability and the prognostic value of hamstring HHD strength measurement in acute hamstring injuries. Methods We measured knee flexion strength with HHD in 75 athletes at 2 visits, at baseline (within 5 days of hamstring injury) and follow-up (5 to 7 days after the baseline measurement). We assessed isometric hamstring strength in 15° and 90° of knee flexion. Reliability analysis testing was performed by 2 testers independently at the follow-up visit. We recorded the time needed to return to play (RTP) up to 6 months following baseline. Results The intraclass correlation coefficients of the strength measurements in injured hamstrings were between 0.75 and 0.83. There was a statistically significant but weak correlation between the time to RTP and the strength deficit at 15° of knee flexion measured at baseline (Spearman r = 0.25, P = .045) and at the follow-up visit (Spearman r = 0.26, P = .034). Up to 7% of the variance in time to RTP is explained by this strength deficit. None of the other strength variables were significantly correlated with time to RTP. Conclusion Hamstring strength can be reliably measured with HHD in athletes with acute hamstring injuries. The prognostic value of strength measurements is limited, as there is only a weak association between the time to RTP and hamstring strength deficit after acute injury. Level of Evidence Prognosis, level 4. J Orthop Sports Phys Ther 2016;46(8):689-696. Epub 12 May 2016. doi:10.2519/jospt.2016.6363.

  11. The disconnected values model improves mental well-being and fitness in an employee wellness program.

    PubMed

    Anshel, Mark H; Brinthaupt, Thomas M; Kang, Minsoo

    2010-01-01

    This study examined the effect of a 10-week wellness program on changes in physical fitness and mental well-being. The conceptual framework for this study was the Disconnected Values Model (DVM). According to the DVM, detecting the inconsistencies between negative habits and values (e.g., health, family, faith, character) and concluding that these "disconnects" are unacceptable promotes the need for health behavior change. Participants were 164 full-time employees at a university in the southeastern U.S. The program included fitness coaching and a 90-minute orientation based on the DVM. Multivariate Mixed Model analyses indicated significantly improved scores from pre- to post-intervention on selected measures of physical fitness and mental well-being. The results suggest that the Disconnected Values Model provides an effective cognitive-behavioral approach to generating health behavior change in a 10-week workplace wellness program.

  12. Comparing multistate expected damages, option price and cumulative prospect measures for valuing flood protection

    NASA Astrophysics Data System (ADS)

    Farrow, Scott; Scott, Michael

    2013-05-01

    Floods are risky events ranging from small to catastrophic. Although expected flood damages are frequently used for economic policy analysis, alternative measures such as option price (OP) and cumulative prospect value exist. The empirical magnitude of these measures whose theoretical preference is ambiguous is investigated using case study data from Baltimore City. The outcome for the base case OP measure increases mean willingness to pay over the expected damage value by about 3%, a value which is increased with greater risk aversion, reduced by increased wealth, and only slightly altered by higher limits of integration. The base measure based on cumulative prospect theory is about 46% less than expected damages with estimates declining when alternative parameters are used. The method of aggregation is shown to be important in the cumulative prospect case which can lead to an estimate up to 41% larger than expected damages. Expected damages remain a plausible and the most easily computed measure for analysts.

  13. Density Measurements of Low Silica CaO-SiO2-Al2O3 Slags

    NASA Astrophysics Data System (ADS)

    Muhmood, Luckman; Seetharaman, Seshadri

    2010-08-01

    Density measurements of a low-silica CaO-SiO2-Al2O3 system were carried out using the Archimedes principle. A Pt 30 pct Rh bob and wire arrangement was used for this purpose. The results obtained were in good agreement with those obtained from the model developed in the current group as well as with other results reported earlier. The density for the CaO-SiO2 and the CaO-Al2O3 binary slag systems also was estimated from the ternary values. The extrapolation of density values for high-silica systems also showed good agreement with previous works. An estimation for the density value of CaO was made from the current experimental data. The density decrease at high temperatures was interpreted based on the silicate structure. As the mole percent of SiO2 was below the 33 pct required for the orthosilicate composition, discrete {text{SiO}}4^{4 - } tetrahedral units in the silicate melt would exist along with O2- ions. The change in melt expansivity may be attributed to the ionic expansions in the order of {text{Al}}^{ 3+ } - {text{O}}^{ 2- } < {text{Ca}}^{ 2+ } - {text{O}}^{ 2- } < {text{Ca}}^{ 2+ } - {text{O}}^{ - } Structural changes in the ternary slag also could be correlated to a drastic change in the value of enthalpy of mixing.

  14. Method and apparatus for real-time measurement of fuel gas compositions and heating values

    DOEpatents

    Zelepouga, Serguei; Pratapas, John M.; Saveliev, Alexei V.; Jangale, Vilas V.

    2016-03-22

    An exemplary embodiment can be an apparatus for real-time, in situ measurement of gas compositions and heating values. The apparatus includes a near infrared sensor for measuring concentrations of hydrocarbons and carbon dioxide, a mid infrared sensor for measuring concentrations of carbon monoxide and a semiconductor based sensor for measuring concentrations of hydrogen gas. A data processor having a computer program for reducing the effects of cross-sensitivities of the sensors to components other than target components of the sensors is also included. Also provided are corresponding or associated methods for real-time, in situ determination of a composition and heating value of a fuel gas.

  15. Automated calibration of laser spectrometer measurements of δ18 O and δ2 H values in water vapour using a Dew Point Generator.

    PubMed

    Munksgaard, Niels C; Cheesman, Alexander W; Gray-Spence, Andrew; Cernusak, Lucas A; Bird, Michael I

    2018-06-30

    Continuous measurement of stable O and H isotope compositions in water vapour requires automated calibration for remote field deployments. We developed a new low-cost device for calibration of both water vapour mole fraction and isotope composition. We coupled a commercially available dew point generator (DPG) to a laser spectrometer and developed hardware for water and air handling along with software for automated operation and data processing. We characterised isotopic fractionation in the DPG, conducted a field test and assessed the influence of critical parameters on the performance of the device. An analysis time of 1 hour was sufficient to achieve memory-free analysis of two water vapour standards and the δ 18 O and δ 2 H values were found to be independent of water vapour concentration over a range of ≈20,000-33,000 ppm. The reproducibility of the standard vapours over a 10-day period was better than 0.14 ‰ and 0.75 ‰ for δ 18 O and δ 2 H values, respectively (1 σ, n = 11) prior to drift correction and calibration. The analytical accuracy was confirmed by the analysis of a third independent vapour standard. The DPG distillation process requires that isotope calibration takes account of DPG temperature, analysis time, injected water volume and air flow rate. The automated calibration system provides high accuracy and precision and is a robust, cost-effective option for long-term field measurements of water vapour isotopes. The necessary modifications to the DPG are minor and easily reversible. Copyright © 2018 John Wiley & Sons, Ltd.

  16. Is Valuing Happiness Associated With Lower Well-Being? A Factor-Level Analysis using the Valuing Happiness Scale

    PubMed Central

    Luhmann, Maike; Necka, Elizabeth A.; Schönbrodt, Felix D.; Hawkley, Louise C.

    2015-01-01

    Recent studies suggest that valuing happiness is negatively associated with well-being. Most of these studies used the Valuing Happiness Scale (Mauss, Tamir, et al., 2011). In the present paper, we examined the factor structure of this scale using data pooled from six independent samples (Ntotal = 938). Exploratory and confirmatory factor analysis showed that the Valuing Happiness Scale is not unidimensional and that only one of its three factors correlates negatively with various indicators of well-being, whereas non-significant or positive correlations were found for the other factors. These findings indicate that valuing happiness may not necessarily be bad for one’s well-being, and call for a better definition, theoretical foundation, and operationalization of this construct. PMID:26778865

  17. SU-E-I-19: CTDI Values for All Protocols: Using the Ratio of the DLP Measured in CTDI Phantoms to the Measured Air Exposure

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Raterman, G; Gauntt, D

    2014-06-01

    Purpose: To propose a method other than CTDI phantom measurements for routine CT dosimetry QA. This consists of taking a series of air exposure measurements and calculating a factor for converting from this exposure measurement to the protocol's associated head or body CTDI value using DLP. The data presented are the ratios of phantom DLP to air exposure ratios for different scanners, as well as error in the displayed CTDI. Methods: For each scanner, the CTDI is measured at all available tube voltages using both the head and body phantoms. Then, the exposure is measured using a pencil chamber inmore » air at isocenter. A ratio of phantom DLP to exposure in air for a given protocol may be calculated and used for converting a simple air dose measurement to a head or body CTDI value. For our routine QA, the exposure in air for different collimations, mAs, and kVp is measured, and displayed CTDI is recorded. Therefore, the ratio calculated may convert these exposures to CTDI values that may then be compared to the displayed CTDI for a large range of acquisition parameter combinations. Results: It was found that all scanners tend to have a ratio factor that slightly increases with kVp. Also, Philips scanners appear to have less of a dependence on kVp; whereas, GE scanners have a lower ratio at lower kVp. The use of air exposure times the DLP conversion yielded CTDI values that were less than 10% different from the displayed CTDI on several scanners. Conclusion: This method may be used as a primary method for CT dosimetry QA. As a result of the ease of measurement, a dosimetry metric specific to that scanner may be calculated for a wide variety of CT protocols, which could also be used to monitor display CTDI value accuracy.« less

  18. The Valued Living Questionnaire: Defining and Measuring Valued Action within a Behavioral Framework

    ERIC Educational Resources Information Center

    Wilson, Kelly G.; Sandoz, Emily K.; Kitchens, Jennifer; Roberts, Miguel

    2010-01-01

    A number of cognitive-behavior therapies now strongly emphasize particular behavioral processes as mediators of clinical change specific to that therapy. This shift in emphasis calls for the development of measures sensitive to changes in the therapies' processes. Among these is acceptance and commitment therapy (ACT), which posits valued living…

  19. The Value of a Well-Being Improvement Strategy

    PubMed Central

    Guo, Xiaobo; Coberley, Carter; Pope, James E.; Wells, Aaron

    2015-01-01

    Objective: The objective of this study is to evaluate effectiveness of a firm's 5-year strategy toward improving well-being while lowering health care costs amidst adoption of a Consumer-Driven Health Plan. Methods: Repeated measures statistical models were employed to test and quantify association between key demographic factors, employment type, year, individual well-being, and outcomes of health care costs, obesity, smoking, absence, and performance. Results: Average individual well-being trended upward by 13.5% over 5 years, monthly allowed amount health care costs declined 5.2% on average per person per year, and obesity and smoking rates declined by 4.8 and 9.7%, respectively, on average each year. The results show that individual well-being was significantly associated with each outcome and in the expected direction. Conclusions: The firm's strategy was successful in driving statistically significant, longitudinal well-being, biometric and productivity improvements, and health care cost reduction. PMID:26461860

  20. What information on measurement uncertainty should be communicated to clinicians, and how?

    PubMed

    Plebani, Mario; Sciacovelli, Laura; Bernardi, Daniela; Aita, Ada; Antonelli, Giorgia; Padoan, Andrea

    2018-02-02

    The communication of laboratory results to physicians and the quality of reports represent fundamental requirements of the post-analytical phase in order to assure the right interpretation and utilization of laboratory information. Accordingly, the International Standard for clinical laboratories accreditation (ISO 15189) requires that "laboratory reports shall include the information necessary for the interpretation of the examination results". Measurement uncertainty (MU) is an inherent property of any quantitative measurement result which express the lack of knowledge of the true value and quantify the uncertainty of a result, incorporating the factors known to influence it. Even if the MU is not included in the report attributes of ISO 15189 and cannot be considered a post-analytical requirement, it is suggested as an information which should facilitate an appropriate interpretation of quantitative results (quantity values). Therefore, MU has two intended uses: for laboratory professionals, it gives information about the quality of measurements, providing evidence of the compliance with analytical performance characteristics; for physicians (and patients) it may help in interpretation of measurement results, especially when values are compared with reference intervals or clinical decision limits, providing objective information. Here we describe the way that MU should be added to laboratory reports in order to facilitate the interpretation of laboratory results and connecting efforts performed within laboratory to provide more accurate and reliable results with a more objective tool for their interpretation by physicians. Copyright © 2018 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  1. Measuring changes in lipid and blood glucose values in the health and wellness program of Prudential Financial, Inc.

    PubMed

    Short, Meghan E; Goetzel, Ron Z; Young, Jared S; Kowlessar, Niranjana M; Liss-Levinson, Rivka C; Tabrizi, Maryam J; Roemer, Enid Chung; Sabatelli, Adriano A; Winick, Keith; Montes, Myrtho; Crighton, K Andrew

    2010-08-01

    To determine the effect of health promotion programs of Prudential Financial, Inc on biometric measures of blood lipids and glucose. Using actual biometric and self-reported measures of blood lipids and glucose values for the employees of Prudential Financial, Inc, we examined 1) the extent to which self-reported lipid and blood glucose values correlate to laboratory data, 2) whether self-reported and measured lipid values differ for physically active and sedentary employees, and 3) whether participation in a disease management program affects employees' lipid measures. We found significant differences in self-reported and measured total cholesterol and low-density lipoprotein values, although these differences and those for all lipid and blood glucose values were not clinically meaningful. Supporting previous clinical studies, high-density lipoprotein values were significantly higher for fitness center users compared with sedentary employees. Finally, disease management participants showed a significant reduction in total cholesterol and low-density lipoprotein during a 3-year period compared with nonparticipants. On average, the employees of Prudential Financial, Inc were aware of and accurately reported their lipid and blood glucose levels. Results from this study support the value of evaluating corporate health promotion programs, using measured biometric outcomes.

  2. Measuring the economic value of wildlife: a caution

    Treesearch

    T. H. Stevens

    1992-01-01

    Wildlife values appear to be very sensitive to whether species are evaluated separately or together, and value estimates often seem inconsistent with neoclassical economic theory. Wildlife value estimates must therefore be used with caution. Additional research about the nature of individual value structures for wildlife is needed.

  3. Anthropometric measurements as predictors of cephalopelvic disproportion: Can the diagnostic accuracy be improved?

    PubMed

    Benjamin, Santosh J; Daniel, Anjali B; Kamath, Asha; Ramkumar, Vani

    2012-01-01

    We assessed the efficacy of maternal anthropometric measurements and clinical estimates of fetal weight in isolation and in combination as predictors of cephalopelvic disproportion (CPD). Prospective cohort study. Tertiary care teaching hospital, two affiliated hospitals with facilities for conducting cesarean delivery and seven affiliated primary care facilities with no operation theaters. Primigravidae over 37 weeks' gestation attending these facilities during a 20-month period with a singleton pregnancy in vertex presentation. Several anthropometric measurements were taken in 249 primigravidae. Fetal weight was estimated. Differences in these measurements between the vaginal delivery and CPD groups were analyzed. The validity of these measurements in predicting CPD was analyzed by plotting receiver operating characteristic curves and by logistic regression analysis. Mode of delivery. Maternal height, foot size, inter-trochanteric diameter and bis-acromial diameter showed the highest positive predictive values for CPD. Combining some maternal measurements with estimates of fetal weight increased predictive values modestly, which are likely to be greater if the estimates of fetal weight are close to the actual birth weight. Based on multivariate analysis the risk factors for CPD in our population were foot length ≤23cm, inter-trochanteric diameter ≤30cm and estimated fetal weight ≥3 000g. Maternal anthropometric measurements can predict CPD to some extent. Combining maternal measurements with clinical estimates of fetal weight only enhances the predictive value to a relatively modest degree (positive predictive value 24%). © 2011 The Authors Acta Obstetricia et Gynecologica Scandinavica © 2011 Nordic Federation of Societies of Obstetrics and Gynecology.

  4. Accuracy of Transcutaneous CO2 Values Compared With Arterial and Capillary Blood Gases.

    PubMed

    Lambert, Laura L; Baldwin, Melissa B; Gonzalez, Cruz Velasco; Lowe, Gary R; Willis, J Randy

    2018-05-08

    Transcutaneous monitors are utilized to monitor a patient's respiratory status. Some patients have similar values when comparing transcutaneous carbon dioxide ( P tcCO 2 ) values with blood gas analysis, whereas others show extreme variability. A retrospective review of data was performed to determine how accurately P tcCO 2 correlated with CO 2 values obtained by arterial blood gas (ABG) or capillary blood gas. To determine whether P tcCO 2 values correlated with ABG or capillary blood gas values, subjects' records were retrospectively reviewed. Data collected included the P tcCO 2 value at the time of blood gas procurement and the ABG or capillary blood gas P CO 2 value. Agreement of pairs of methods (ABG vs P tcCO 2 and capillary blood gas vs P tcCO 2 ) was assessed with the Bland-Altman approach with limits of agreement estimated with a mixed model to account for serial measurements per subject. A total of 912 pairs of ABG/ P tcCO 2 values on 54 subjects and 307 pairs of capillary blood gas/ P tcCO 2 values on 34 subjects were analyzed. The P CO 2 range for ABG was 24-106 mm Hg, and P tcCO 2 values were 27-133 mm Hg. The P CO 2 range for capillary blood gas was 29-108 mm Hg, and P tcCO 2 values were 30-103 mm Hg. For ABG/ P tcCO 2 comparisons, the Pearson correlation coefficient was 0.82, 95% CI was 0.80-0.84, and P was <.001. For capillary blood gas/ P tcCO 2 comparisons, the Pearson correlation coefficient was 0.77, 95% CI was 0.72-0.81, and P was <.001. For ABG/ P tcCO 2 , the estimated difference ± SD was -6.79 t± 7.62 mm Hg, and limits of agreement were -22.03 to 8.45. For capillary blood gas/ P tcCO 2 , the estimated difference ± SD was -1.61 ± 7.64 mm Hg, and limits of agreement were -16.88 to 13.66. The repeatability coefficient was about 30 mm Hg. Based on these data, capillary blood gas comparisons showed less variation and a slightly lower correlation with P tcCO 2 than did ABG comparisons. After accounting for serial measurements per patient

  5. Measuring the value of groundwater and other forms of natural capital

    PubMed Central

    Fenichel, Eli P.; Abbott, Joshua K.; Bayham, Jude; Boone, Whitney; Haacker, Erin M. K.; Pfeiffer, Lisa

    2016-01-01

    Valuing natural capital is fundamental to measuring sustainability. The United Nations Environment Programme, World Bank, and other agencies have called for inclusion of the value of natural capital in sustainability metrics, such as inclusive wealth. Much has been written about the importance of natural capital, but consistent, rigorous valuation approaches compatible with the pricing of traditional forms of capital have remained elusive. We present a guiding quantitative framework enabling natural capital valuation that is fully consistent with capital theory, accounts for biophysical and economic feedbacks, and can guide interdisciplinary efforts to measure sustainability. We illustrate this framework with an application to groundwater in the Kansas High Plains Aquifer, a rapidly depleting asset supporting significant food production. We develop a 10-y time series (1996−2005) of natural capital asset prices that accounts for technological, institutional, and physical changes. Kansas lost approximately $110 million per year (2005 US dollars) of capital value through groundwater withdrawal and changes in aquifer management during the decade spanning 1996–2005. This annual loss in wealth is approximately equal to the state’s 2005 budget surplus, and is substantially more than investments in schools over this period. Furthermore, real investment in agricultural capital also declined over this period. Although Kansas’ depletion of water wealth is substantial, it may be tractably managed through careful groundwater management and compensating investments in other natural and traditional assets. Measurement of natural capital value is required to inform management and ongoing investments in natural assets. PMID:26858431

  6. Protocol for fermionic positive-operator-valued measures

    NASA Astrophysics Data System (ADS)

    Arvidsson-Shukur, D. R. M.; Lepage, H. V.; Owen, E. T.; Ferrus, T.; Barnes, C. H. W.

    2017-11-01

    In this paper we present a protocol for the implementation of a positive-operator-valued measure (POVM) on massive fermionic qubits. We present methods for implementing nondispersive qubit transport, spin rotations, and spin polarizing beam-splitter operations. Our scheme attains linear opticslike control of the spatial extent of the qubits by considering ground-state electrons trapped in the minima of surface acoustic waves in semiconductor heterostructures. Furthermore, we numerically simulate a high-fidelity POVM that carries out Procrustean entanglement distillation in the framework of our scheme, using experimentally realistic potentials. Our protocol can be applied not only to pure ensembles with particle pairs of known identical entanglement, but also to realistic ensembles of particle pairs with a distribution of entanglement entropies. This paper provides an experimentally realizable design for future quantum technologies.

  7. Reproducibility, interrater agreement, and age-related changes of fractional anisotropy measures at 3T in healthy subjects: effect of the applied b-value.

    PubMed

    Bisdas, S; Bohning, D E; Besenski, N; Nicholas, J S; Rumboldt, Z

    2008-06-01

    There is no reproducibility study of fractional anisotropy (FA) measurements at 3T using regions of interest (ROIs). Our purpose was to establish the extent and statistical significance of the interrater variability, the variability observed with 2 different b-values, and in 2 separate scanning sessions. Twelve healthy volunteers underwent MR imaging twice. MR imaging was performed on a 3T unit, and FA maps were analyzed independently by 2 observers using ROIs positioned in the corpus callosum, internal capsules, corticospinal tracts, and right thalamus. Changes in FA values (x10(3)) measured with 2 b-values (700 and 1000 s/mm(2)), age-related differences, interobserver agreement, and measurement reproducibility were assessed. In the right internal capsule genu (FA = 702/728; b = 1000/700 s/mm(2)) and the left anterior limb of the internal capsule (AIC; FA = 617/745; b = 1000/700 s/mm(2)), the FA values were significantly different between the 2 b-values (P = .02 and .05, respectively). Significant age-related differences in FA were observed in the genu of the corpus callosum and in the left AIC. Interrater measurements showed fair-to-moderate agreement for most anatomic structures. The lowest significant change for a single subject regarding any FA values between the 2 sessions was in the corpus callosum (4%), whereas the highest one was in the corticospinal tracts (27%). The Bland-Altman plot analysis showed that the 1000-s/mm(2) b-value gave satisfactorily reproducible measurements equally good or better than the 700-s/mm(2) b-value. The reproducibility of FA estimates using ROIs was satisfactory. Measurements with a b-value at 1000 s/mm(2) showed superior reproducibility in most anatomic locations.

  8. On the value-dependence of value-driven attentional capture.

    PubMed

    Anderson, Brian A; Halpern, Madeline

    2017-05-01

    Findings from an increasingly large number of studies have been used to argue that attentional capture can be dependent on the learned value of a stimulus, or value-driven. However, under certain circumstances attention can be biased to select stimuli that previously served as targets, independent of reward history. Value-driven attentional capture, as studied using the training phase-test phase design introduced by Anderson and colleagues, is widely presumed to reflect the combined influence of learned value and selection history. However, the degree to which attentional capture is at all dependent on value learning in this paradigm has recently been questioned. Support for value-dependence can be provided through one of two means: (1) greater attentional capture by prior targets following rewarded training than following unrewarded training, and (2) greater attentional capture by prior targets previously associated with high compared to low value. Using a variant of the original value-driven attentional capture paradigm, Sha and Jiang (Attention, Perception, and Psychophysics, 78, 403-414, 2016) failed to find evidence of either, and raised criticisms regarding the adequacy of evidence provided by prior studies using this particular paradigm. To address this disparity, here we provided a stringent test of the value-dependence hypothesis using the traditional value-driven attentional capture paradigm. With a sufficiently large sample size, value-dependence was observed based on both criteria, with no evidence of attentional capture without rewards during training. Our findings support the validity of the traditional value-driven attentional capture paradigm in measuring what its name purports to measure.

  9. On the Value-Dependence of Value-Driven Attentional Capture

    PubMed Central

    Anderson, Brian A.; Halpern, Madeline

    2017-01-01

    Findings from an increasingly large number of studies have been used to argue that attentional capture can be dependent on the learned value of a stimulus, or value-driven. However, under certain circumstances attention can be biased to select stimuli that previously served as targets, independent of reward history. Value-driven attentional capture, as studied using the training phase-test phase design introduced by Anderson and colleagues, is widely presumed to reflect the combined influence of learned value and selection history. However, the degree to which attentional capture is at all dependent on value learning in this paradigm has recently been questioned. Support for value-dependence can be provided through one of two means: (1) greater attentional capture by prior targets following rewarded training than following unrewarded training, and (2) greater attentional capture by prior targets previously associated with high compared to low value. Using a variant of the original value-driven attentional capture paradigm, Sha and Jiang (2016) failed to find evidence of either, and raised criticisms regarding the adequacy of evidence provided by prior studies using this particular paradigm. To address this disparity, here we provided a stringent test of the value-dependence hypothesis using the traditional value-driven attentional capture paradigm. With a sufficiently large sample size, value-dependence was observed based on both criteria, with no evidence of attentional capture without rewards during training. Our findings support the validity of the traditional value-driven attentional capture paradigm in measuring what its name purports to measure. PMID:28176215

  10. Calculating meal glycemic index by using measured and published food values compared with directly measured meal glycemic index.

    PubMed

    Dodd, Hayley; Williams, Sheila; Brown, Rachel; Venn, Bernard

    2011-10-01

    Glycemic index (GI) testing is normally based on individual foods, whereas GIs for meals or diets are based on a formula using a weighted sum of the constituents. The accuracy with which the formula can predict a meal or diet GI is questionable. Our objective was to compare the GI of meals, obtained by using the formula and by using both measured food GI and published values, with directly measured meal GIs. The GIs of 7 foods were tested in 30 healthy people. The foods were combined into 3 meals, each of which provided 50 g available carbohydrate, including a staple (potato, rice, or spaghetti), vegetables, sauce, and pan-fried chicken. The mean (95% CI) meal GIs determined from individual food GI values and by direct measurement were as follows: potato meal [predicted, 63 (56, 70); measured, 53 (46, 62)], rice meal [predicted, 51 (45, 56); measured, 38 (33, 45)], and spaghetti meal [predicted, 54 (49, 60); measured, 38 (33, 44)]. The predicted meal GIs were all higher than the measured GIs (P < 0.001). The extent of the overestimation depended on the particular food, ie, 12, 15, and 19 GI units (or 22%, 40%, and 50%) for the potato, rice, and spaghetti meals, respectively. The formula overestimated the GI of the meals by between 22% and 50%. The use of published food values also overestimated the measured meal GIs. Investigators using the formula to calculate a meal or diet GI should be aware of limitations in the method. This trial is registered with the Australian and New Zealand Clinical Trials Registry as ACTRN12611000210976.

  11. Determinination of plasma osmolality and agreement between measured and calculated values in healthy adult Hispaniolan Amazon parrots (Amazona ventralis).

    PubMed

    Acierno, Mark J; Mitchell, Mark A; Freeman, Diana M; Schuster, Patricia J; Guzman, David Sanchez-Migallon; Tully, Thomas N

    2009-09-01

    To determine plasma osmolality in healthy adult Hispaniolan Amazon parrots (Amazona ventralis) and validate osmolality equations in these parrots. 20 healthy adult Hispaniolan Amazon parrots. A blood sample (0.5 mL) was collected from the right jugular vein of each parrot and placed into a lithium heparin microtainer tube. Samples were centrifuged, and plasma was harvested and frozen at -30 degrees C. Samples were thawed, and plasma osmolality was measured in duplicate with a freezing-point depression osmometer. The mean value was calculated for the 2 osmolality measurements. Plasma osmolality values were normally distributed, with a mean +/- SD of 326.0 +/- 6.878 mOsm/kg. The equations (2 x [Na(+) + K(+)]) + (glucose/18), which resulted in bias of 2.3333 mOsm/kg and limits of agreement of -7.0940 to 11.7606 mOsm/kg, and (2 x [Na(+) + K(+)]) + (uric acid concentration/16.8) + (glucose concentration/18), which resulted in bias of 5.8117 mOsm/kg and limits of agreement of -14.6640 to 3.0406 mOsm/kg, yielded calculated values that were in good agreement with the measured osmolality. IV administration of large amounts of hypotonic fluids can have catastrophic consequences. Osmolality of the plasma from parrots in this study was significantly higher than that of commercially available prepackaged fluids. Therefore, such fluids should be used with caution in Hispaniolan Amazon parrots as well as other psittacines. Additional studies are needed to determine whether the estimation of osmolality has the same clinical value in psittacines as it does in other animals.

  12. 29 CFR 4281.12 - Benefits to be valued.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Benefits to be valued. 4281.12 Section 4281.12 Labor Regulations Relating to Labor (Continued) PENSION BENEFIT GUARANTY CORPORATION INSOLVENCY, REORGANIZATION, TERMINATION, AND OTHER RULES APPLICABLE TO MULTIEMPLOYER PLANS DUTIES OF PLAN SPONSOR FOLLOWING MASS...

  13. Should Social Value Obligations be Local or Global?

    PubMed

    Nayak, Rahul; Shah, Seema K

    2017-02-01

    According to prominent bioethics scholars and international guidelines, researchers and sponsors have obligations to ensure that the products of their research are reasonably available to research participants and their communities. In other words, the claim is that research is unethical unless it has local social value. In this article, we argue that the existing conception of reasonable availability should be replaced with a social value obligation that extends to the global poor (and not just research participants and host communities). To the extent the social value requirement has been understood as geographically constrained to the communities that host research and the countries that can afford the products of research, it has neglected to include the global poor as members of the relevant society. We argue that a new conception of social value obligations is needed for two reasons. First, duties of global beneficence give reason for researchers, sponsors, and institutions to take steps to make their products more widely accessible. Second, public commitments made by many institutions acknowledge and engender responsibilities to make the products of research more accessible to the global poor. Future research is needed to help researchers and sponsors discharge these obligations in ways that unlock their full potential. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.

  14. Can lung function measurements be used to predict which patients will be at risk of developing interstitial pneumonitis after bone marrow transplantation?

    PubMed

    Milburn, H J; Prentice, H G; du Bois, R M

    1992-06-01

    Lung function often deteriorates after bone marrow transplantation for haematological malignancies. Whether pulmonary function measurements are useful for monitoring patients' progress after transplantation and for alerting clinicians to the development of pneumonitis is uncertain. Serial pulmonary function measurements were made in 39 patients with a haematological malignancy, and the values from 18 recipients of T cell depleted allogeneic (n = 17) or autologous (n = 1) bone marrow transplants who developed interstitial pneumonitis were compared retrospectively with values from 21 recipients of allogeneic (n = 17) or autologous (n = 4) transplants who did not develop pneumonitis. Lung function was measured at the onset of a further 18 episodes of pneumonitis. Measurements made before transplantation showed no difference in forced expiratory volume in one second (FEV1), transfer factor for carbon monoxide (TLCO), or total lung capacity between the two groups, but the forced vital capacity (FVC) was slightly higher in those who developed pneumonitis (mean (SD)% predicted 104 (12)) than in those who did not (93 (17%)). Six weeks and three months after transplantation all pulmonary function measurements had fallen slightly in both groups but TLCO had fallen considerably more in those who later developed pneumonitis, being 71% (SD 11%) and 77% (7%) of pretransplant values in patients who later developed pneumonitis compared with 109% (38%) and 96% (26%) in those who did not. All lung function measurements were significantly lower at the onset of pneumonitis than three months after transplantation, even in patients with no abnormal signs and a normal chest radiograph. Serial measurements of gas transfer before and after bone marrow transplantation may be useful for predicting which patients will be at risk of developing pneumonitis and may help to diagnose pneumonitis in breathless patients with no abnormal signs.

  15. The Math–Biology Values Instrument: Development of a Tool to Measure Life Science Majors’ Task Values of Using Math in the Context of Biology

    PubMed Central

    Andrews, Sarah E.; Runyon, Christopher; Aikens, Melissa L.

    2017-01-01

    In response to calls to improve the quantitative training of undergraduate biology students, there have been increased efforts to better integrate math into biology curricula. One challenge of such efforts is negative student attitudes toward math, which are thought to be particularly prevalent among biology students. According to theory, students’ personal values toward using math in a biological context will influence their achievement and behavioral outcomes, but a validated instrument is needed to determine this empirically. We developed the Math–Biology Values Instrument (MBVI), an 11-item college-level self-­report instrument grounded in expectancy-value theory, to measure life science students’ interest in using math to understand biology, the perceived usefulness of math to their life science career, and the cost of using math in biology courses. We used a process that integrates multiple forms of validity evidence to show that scores from the MBVI can be used as a valid measure of a student’s value of math in the context of biology. The MBVI can be used by instructors and researchers to help identify instructional strategies that influence math–biology values and understand how math–biology values are related to students’ achievement and decisions to pursue more advanced quantitative-based courses. PMID:28747355

  16. Comparison of CO2 in air versus carbogen for the measurement of cerebrovascular reactivity with magnetic resonance imaging.

    PubMed

    Hare, Hannah V; Germuska, Michael; Kelly, Michael E; Bulte, Daniel P

    2013-11-01

    Measurement of cerebrovascular reactivity (CVR) can give valuable information about existing pathology and the risk of adverse events, such as stroke. A common method of obtaining regional CVR values is by measuring the blood flow response to carbon dioxide (CO2)-enriched air using arterial spin labeling (ASL) or blood oxygen level-dependent (BOLD) imaging. Recently, several studies have used carbogen gas (containing only CO2 and oxygen) as an alternative stimulus. A direct comparison was performed between CVR values acquired by ASL and BOLD imaging using stimuli of (1) 5% CO2 in air and (2) 5% CO2 in oxygen (carbogen-5). Although BOLD and ASL CVR values are shown to be correlated for CO2 in air (mean response 0.11±0.03% BOLD, 4.46±1.80% ASL, n=16 hemispheres), this correlation disappears during a carbogen stimulus (0.36±0.06% BOLD, 4.97±1.30% ASL). It is concluded that BOLD imaging should generally not be used in conjunction with a carbogen stimulus when measuring CVR, and that care must be taken when interpreting CVR as measured by ASL, as values obtained from different stimuli (CO2 in air versus carbogen) are not directly comparable.

  17. Development and validation of a measure of food choice values.

    PubMed

    Lyerly, Jordan E; Reeve, Charlie L

    2015-06-01

    Food choice values (FCVs) are factors that individuals consider when deciding which foods to purchase and/or consume. Given the potentially important implications for health, it is critical for researchers to have access to a validated measure of FCV. Though there is an existing measure of FCV, this measure was developed 20 years ago and recent research suggests additional FCVs exist that are not included in this measure. A series of four studies was conducted to develop a new expanded measure of FCV. An eight-factor model of FCV was supported and confirmed. In aggregate, results from the four studies indicate that the measure is content valid, and has internally consistent scales that also demonstrated acceptable temporal stability and convergent validity. In addition, the eight scales of the measures were independent of social desirability, met criteria for measurement invariance across income groups, and predicted dietary intake. The development of this new measure of FCV may be useful for researchers examining FCVs (FCVs) in the future, as well as for use in intervention and prevention efforts targeting dietary choices. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Establishment of a Method to Measure Length of the Ulnar Nerve and Standardize F-wave Values in Clinically Normal Beagles

    PubMed Central

    HIRASAWA, Shun; SHIMIZU, Miki; MARUI, Yuumi; KISHIMOTO, Miori; OKUNO, Seiichi

    2014-01-01

    We designed a new method of measuring the length of the ulnar nerve and determining standard values for F-wave parameters of the ulnar nerve in clinically normal beagles. Nerve length must be precisely measured to determine F-wave latency and conduction velocity. The length of the forelimb has served as the length of the ulnar nerve for F-wave assessments, but report indicates that F-wave latency is proportional to the length of the pathway traveled by nerve impulses. Therefore, we measured the surface distance from a stimulus point to the spinous process of the first thoracic vertebra (nerve length 1) and the anterior horn of the scapula (nerve length 2) as landmarks through the olecranon and the shoulder blade acromion. The correlation coefficients between the shortest F-wave latency and the length of nerves 1, 2 or the forelimb were 0.61, 0.7 and 0.58. Nerve length 2 generated the highest value. Furthermore, the anterior horn of the scapula was easily palpated in any dog regardless of well-fed body. We concluded that nerve length 2 was optimal for measuring the length of the ulnar nerve. PMID:25649942

  19. Measuring Success in Health Care Value-Based Purchasing Programs

    PubMed Central

    Damberg, Cheryl L.; Sorbero, Melony E.; Lovejoy, Susan L.; Martsolf, Grant R.; Raaen, Laura; Mandel, Daniel

    2014-01-01

    Abstract Value-based purchasing (VBP) refers to a broad set of performance-based payment strategies that link financial incentives to health care providers' performance on a set of defined measures in an effort to achieve better value. The U.S. Department of Health and Human Services is advancing the implementation of VBP across an array of health care settings in the Medicare program in response to requirements in the 2010 Patient Protection and Affordable Care Act, and policymakers are grappling with many decisions about how best to design and implement VBP programs so that they are successful in achieving stated goals. This article summarizes the current state of knowledge about VBP based on a review of the published literature, a review of publicly available documentation from VBP programs, and discussions with an expert panel composed of VBP program sponsors, health care providers and health systems, and academic researchers with VBP evaluation expertise. Three types of VBP models were the focus of the review: (1) pay-for-performance programs, (2) accountable care organizations, and (3) bundled payment programs. The authors report on VBP program goals and what constitutes success; the evidence on the impact of these programs; factors that characterize high– and low–performing providers in VBP programs; the measures, incentive structures, and benchmarks used by VBP programs; evidence on spillover effects and unintended consequences; and gaps in the knowledge base. PMID:28083347

  20. The vexing problem of defining the meaning, role and measurement of values in treatment decision-making.

    PubMed

    Charles, Cathy; Gafni, Amiram

    2014-03-01

    Two international movements, evidence-based medicine (EBM) and shared decision-making (SDM) have grappled for some time with issues related to defining the meaning, role and measurement of values/preferences in their respective models of treatment decision-making. In this article, we identify and describe unresolved problems in the way that each movement addresses these issues. The starting point for this discussion is that at least two essential ingredients are needed for treatment decision-making: research information about treatment options and their potential benefits and risks; and the values/preferences of participants in the decision-making process. Both the EBM and SDM movements have encountered difficulties in defining the meaning, role and measurement of values/preferences in treatment decision-making. In the EBM model of practice, there is no clear and consistent definition of patient values/preferences and no guidance is provided on how to integrate these into an EBM model of practice. Methods advocated to measure patient values are also problematic. Within the SDM movement, patient values/preferences tend to be defined and measured in a restrictive and reductionist way as patient preferences for treatment options or attributes of options, while broader underlying value structures are ignored. In both models of practice, the meaning and expected role of physician values in decision-making are unclear. Values clarification exercises embedded in patient decision aids are suggested by SDM advocates to identify and communicate patient values/preferences for different treatment outcomes. Such exercises have the potential to impose a particular decision-making theory and/or process onto patients, which can change the way they think about and process information, potentially impeding them from making decisions that are consistent with their true values. The tasks of clarifying the meaning, role and measurement of values/preferences in treatment decision

  1. CBF measured by Xe-CT: Approach to analysis and normal values

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yonas, H.; Darby, J.M.; Marks, E.C.

    1991-09-01

    Normal reference values and a practical approach to CBF analysis are needed for routine clinical analysis and interpretation of xenon-enhanced computed tomography (CT) CBF studies. The authors measured CBF in 67 normal individuals with the GE 9800 CT scanner adapted for CBF imaging with stable Xe. CBF values for vascular territories were systematically analyzed using the clustering of contiguous 2-cm circular regions of interest (ROIs) placed within the cortical mantle and basal ganglia. Mixed cortical flows averaged 51 {plus minus} 10ml.100g-1.min-1. High and low flow compartments, sampled by placing 5-mm circular ROIs in regions containing the highest and lowest flowmore » values in each hemisphere, averaged 84 {plus minus} 14 and 20 {plus minus} 5 ml.100 g-1.min-1, respectively. Mixed cortical flow values as well as values within the high flow compartment demonstrated significant decline with age; however, there were no significant age-related changes in the low flow compartment. The clustering of systematically placed cortical and subcortical ROIs has provided a normative data base for Xe-CT CBF and a flexible and uncomplicated method for the analysis of CBF maps generated by Xe-enhanced CT.« less

  2. Measurement of radiation dose with BeO dosimeters using optically stimulated luminescence technique in radiotherapy applications.

    PubMed

    Şahin, Serdar; Güneş Tanır, A; Meriç, Niyazi; Aydınkarahaliloğlu, Ercan

    2015-09-01

    The radiation dose delivered to the target by using different radiotherapy applications has been measured with the help of beryllium oxide (BeO) dosimeters to be placed inside the rando phantom. Three-Dimensional Conformal Radiotherapy (3DCRT), Intensity-Modulated Radiotherapy (IMRT) and Intensity-Modulated Arc Therapy (IMAT) have been used as radiotherapy application. Individual treatment plans have been made for the three radiotherapy applications of rando phantom. The section 4 on the phantom was selected as target and 200 cGy doses were delivered. After the dosimeters placed on section 4 (target) and the sections 2 and 6 (non-target) were irradiated, the result was read through the OSL technique on the Risø TL/OSL system. This procedure was repeated three times for each radiotherapy application. The doses delivered to the target and the non-target sections as a result of the 3DCRT, IMRT and IMAT plans were analyzed. The doses received by the target were measured as 204.71 cGy, 204.76 cGy and 205.65 cGy, respectively. The dose values obtained from treatment planning system (TPS) were compared to the dose values obtained using the OSL technique. It has been concluded that, the radiation dose can be measured with the OSL technique by using BeO dosimeters in medical practices. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. The Bungee Jumper: A Comparison of Predicted and Measured Values

    NASA Astrophysics Data System (ADS)

    Biezeveld, Hubert

    2003-04-01

    The greater-than-g acceleration of a bungee jumper discussed in a previous article in this journal by Kagan and Kott led to many lively discussions among Dutch physics teachers. These inspired me to look for an inexpensive experimental setup, suitable for use in a high school physics class, that can be used to confirm that indeed the acceleration is greater than g. In this paper I describe an exercise to compare the predicted and the measured graphs for the displacement y(t) of the jumper and the force Fb(t) exerted by the bungee on the bridge to which it is fastened. In my apparatus, the "bungee" consists of a light chain and the "jumper" is a small piece of brass. Data collection and the calculation of predicted values were carried out using Coach.2 The analysis reliably leads to the conclusion that the acceleration of the falling jumper does indeed exceed g.

  4. Measuring the Absorption Rate of CO 2 in Nonaqueous CO 2 -Binding Organic Liquid Solvents with a Wetted-Wall Apparatus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mathias, Paul M.; Zheng, Feng; Heldebrant, David J.

    2015-09-17

    The kinetics of the absorption of CO 2 into two nonaqueous CO 2-binding organic liquid (CO 2BOL) solvents were measured at T=35, 45, and 55 °C with a wetted-wall column. Selected CO 2 loadings were run with a so-called “first-generation” CO 2BOL, comprising an independent base and alcohol, and a “second-generation” CO 2BOL, in which the base and alcohol were conjoined. Liquid-film mass-transfer coefficient (k'g) values for both solvents were measured to be comparable to values for monoethanolamine and piperazine aqueous solvents under a comparable driving force, in spite of far higher solution viscosities. An inverse temperature dependence of themore » k'g value was also observed, which suggests that the physical solubility of CO 2 in organic liquids may be making CO 2 mass transfer faster than expected. Aspen Plus software was used to model the kinetic data and compare the CO 2 absorption behavior of nonaqueous solvents with that of aqueous solvent platforms. This work continues our development of the CO2BOL solvents. Previous work established the thermodynamic properties related to CO 2 capture. The present paper quantitatively studies the kinetics of CO 2 capture and develops a rate-based model.« less

  5. Prognostic value of repeated serum CA 125 measurements in first trimester pregnancy.

    PubMed

    Schmidt, T; Rein, D T; Foth, D; Eibach, H W; Kurbacher, C M; Mallmann, P; Römer, T

    2001-08-01

    To assess the diagnostic value of maternal CA 125 in patients with symptomatic first trimester pregnancy and to evaluate the prognostic significance of CA 125 versus beta-hCG in early pregnancies with intact fetal heartbeat, complicated by vaginal bleeding. Two prospective open-label studies with longitudinal follow-up in the second trial. Academic Department of Obstetrics and Gynecology, University of Cologne. Study 1: 168 patients presenting between gestational weeks 6 and 12 with: extrauterine pregnancy, 29; missed abortion, 50; incomplete spontaneous abortion, 38; imminent abortion, 33; and normal pregnancy (no history of endometriosis or ovarian mass), 18. Study 2: Fifty consecutive patients with vaginal bleeding during gestational weeks 6-12 all of whom having demostrable fetal heartbeat. Eighteen patients finally aborted whereas the remainder had normally continuing pregnancy until term. Study 1: Single serum determinations of CA 125 and beta-hCG were correlated with the different disorders observed. Study 2: Two sequential measurements of serum CA 125 and beta-hCG performed within a 5-7 days interval were related to the outcome of pregnancy as indicated by changes of the ultrasound presentation, miscarriage, future hospitalization, or delivery. Study 1: Patients with vaginal bleeding generally had higher median CA 125 values (38 IU/ml; range 1.3-540) compared to non-bleeding patients (17.8 IU/ml; range 1.0-157). No statistically significant differences in regard to median serum CA 125 levels between symptomatic and normal pregnancies occurred: normal pregnancy, 25.5 IU/ml (range 3.2-97); ectopic pregnancy, 26 IU/ml (range 1.3-157); missed abortion, 19.1IU/ml (range 1-242); threatened abortion, 48 IU/ml (range 5.2-540); spontaneous abortion, 40 IU/ml (range 5.4-442). Study 2: Initial CA 125 levels did not differ significantly between both groups of patients with 27/32 non-aborters and 13/18 aborters showing concentrations below 65 IU/ml. After 5-7 days, CA

  6. Measurement value analysis overall equipment effectiveness (OEE) packaging process in line 2 (Case Study of PT. MBI Tbk)

    NASA Astrophysics Data System (ADS)

    Rimawan, Erry; Kholil, Muhammad; Hendri

    2018-03-01

    PT. MBI Tbk is engaged in the manufacture of beverage industry, where the company’s production is based on the magnitude of customer demand that is marketing offices that had been scattered in various regions of Indonesia. In the packaging process steps in PT.MBI through the line 3 lines including racking, canning line, bottling line. In the canning process to existing packing on Line 2 (canning line), there are some machines that are used continuously, among other Depalletizer machine, filler machine, can seamer machine, pasteurizer machine, machine FLD, Wrap Around engine, engine Shrink Wrap. Due to the large demand from customers that is relentless, therefore the calculation of overall equipment effectiveness (OEE) as a whole on line 2 (canning line) is needed in order to make improvements continuously (Continuous Improvement) at line 2 (canning line). This study aims to determine the value of overall equipment effectiveness (OEE) and Losses of the most influential of the big six OEE Losses focused on equipment or machinery as a whole into a single unit that is on the line 2, which will then be known root cause of the losses that occur from the research over the field. From the calculation of overall equipment effectiveness (OEE), there are two ratios are still poor and under world-class standards, while the ratio of the availability of 88.85% of the world-class standards by 90% and the performance ratio of 78.51% of the standard world class by 95%, whereas for quality ratio has entered the world-class standard that is equal to 99.90%. Thus the value of OEE on Line 2 line is below world class standards. In this study there were only five losses, which can be identified, and while the losses were very influential, namely the Speed Reduced Losses, losses, these losses accounted for the largest percentage of the value of the rate of 19.12%, of the results of this study losses occurred due to poor surveillance systems (less good) that causes the employee or

  7. Measuring the Value of Placements to Employers: A Cost-Benefit Approach

    ERIC Educational Resources Information Center

    Wond, Tracey; Rambukwella, Shan

    2018-01-01

    This article explores the concept and measurement of placement value, underexplored in theory and practice to date. The article makes a theoretical contribution to the placement value discourse by examining and articulating the placement value concept. It also offers a practical contribution by exploring a piloted tool to evaluate employer…

  8. Transcutaneous oxygen pressure measurement in diabetic foot ulcers: mean values and cut-point for wound healing.

    PubMed

    Yang, Chuan; Weng, Huan; Chen, Lihong; Yang, Haiyun; Luo, Guangming; Mai, Lifang; Jin, Guoshu; Yan, Li

    2013-01-01

    The purpose of this study was to investigate mean values and cut-point of transcutaneous oxygen pressure (TcPO2) measurement in patients with diabetic foot ulcers. Prospective, descriptive study. Sixty-one patients with diabetes mellitus and foot ulcers comprised the sample. The research setting was Sun Yat-sen Memorial Hospital of SunYat-sen University, Guangzhou, China. Participants underwent transcutaneous oxygen (TcPO2) measurement at the dorsum of foot. Patients were classified into 3 groups according to clinical outcomes: (1) ulcers healed with intact skin group, (2) ulcer improved, and (3) ulcer failed to improve. TcPO2 was assessed and cut-points for predicting diabetic foot ulcer healing were calculated. Thirty-six patients healed with intact skin, 8 experienced improvement, and 17 showed no improvement. Mean TcPO2 levels were significantly higher (P< .001) in healed ulcers with intact skin (32 ± 10 mmHg) when compared to the improvement group (30 ± 7 mmHg) and the nonhealing group (15 ± 12 mmHg). All patients with TcPO2≤ 10 mmHg failed to heal or experienced deterioration in their foot ulcers. In contrast, all patients with TcPO2≥ 40 mmHg achieved wound closure. Measurement of TcPO2 in the supine position revealed a cut-point value of 25 mmHg as the best threshold for predicting diabetic foot ulcer healing; the area under the curve using this cut-point was 0.838 (95% confidence interval = 0.700-0.976). The sensitivity, specificity, positive predictive value, and negative predictive value for TxPO2 were 88.6%, 82.4%, 90.7%, and 72.2%, respectively. TcPO2≥ 40 mmHg was associated with diabetic foot ulcer healing, but a TcPO2≤ 10 mmHg was associated with failure of wound healing. We found that a cut-point of 25 mmHg was most predictive of diabetic foot ulcer healing.

  9. The Core Values that Support Health, Safety, and Well-being at Work

    PubMed Central

    Zwetsloot, Gerard I.J.M.; Scheppingen, Arjella R. van; Bos, Evelien H.; Dijkman, Anja; Starren, Annick

    2013-01-01

    Background Health, safety, and well-being (HSW) at work represent important values in themselves. It seems, however, that other values can contribute to HSW. This is to some extent reflected in the scientific literature in the attention paid to values like trust or justice. However, an overview of what values are important for HSW was not available. Our central research question was: what organizational values are supportive of health, safety, and well-being at work? Methods The literature was explored via the snowball approach to identify values and value-laden factors that support HSW. Twenty-nine factors were identified as relevant, including synonyms. In the next step, these were clustered around seven core values. Finally, these core values were structured into three main clusters. Results The first value cluster is characterized by a positive attitude toward people and their “being”; it comprises the core values of interconnectedness, participation, and trust. The second value cluster is relevant for the organizational and individual “doing”, for actions planned or undertaken, and comprises justice and responsibility. The third value cluster is relevant for “becoming” and is characterized by the alignment of personal and organizational development; it comprises the values of growth and resilience. Conclusion The three clusters of core values identified can be regarded as “basic value assumptions” that underlie both organizational culture and prevention culture. The core values identified form a natural and perhaps necessary aspect of a prevention culture, complementary to the focus on rational and informed behavior when dealing with HSW risks. PMID:24422174

  10. Penetration depth of MgB2 measured using Josephson junctions and SQUIDs

    NASA Astrophysics Data System (ADS)

    Cunnane, Daniel; Zhuang, Chenggang; Chen, Ke; Xi, X. X.; Yong, Jie; Lemberger, T. R.

    2013-02-01

    The penetration depth of MgB2 was measured using two methods of different mechanisms. The first method used MgB2 Josephson junctions and the magnetic field dependence of the junction critical current. The second method deduced the penetration depth from the inductance of a MgB2 microstrip used to modulate the voltage of a MgB2 DC SQUID. The two methods showed a consistent value of the low-temperature penetration depth for MgB2 to be about 40 nm. Both the small penetration depth value and its temperature dependence are in agreement with a microscopic theory for MgB2 in the clean limit.

  11. Changes in the T2 value of cartilage after meniscus transplantation over 1 year.

    PubMed

    Park, Sun-Young; Lee, Sang Hoon; Lee, Min Hee; Chung, Hye Won; Shin, Myung Jin

    2017-04-01

    To evaluate the changes in the mean T2 values of articular cartilage on serial follow-up images up to 1 year in patients who underwent lateral meniscus allograft transplantation (MAT). Fifty-two patients who underwent lateral MAT surgery at our hospital were evaluated preoperatively and at 2 days, 6 weeks, 3 months, 6 months, and 1 year after MAT using 3.0-T magnetic resonance imaging (MRI) that included T2 mapping. T2 value changes according to the arthroscopic grading of chondromalacia were evaluated in the lateral and medial compartment. Lysholm scores were obtained pre- and postoperatively. The T2 values of cartilage were significantly increased 2 days after operation, and then gradually reduced to the baseline level after 1 year in both compartments. In morphologic assessment performed after 1 year, most areas (92.9 %) showed no interval change of chondromalacia grade. Lyshom knee scores increased significantly from the mean preoperative value of 62.5 (range, 23-95) to 89.7 (range, 64-100) at 1 year (p < 0.001). Mean T2 values of cartilage following MAT exhibited a return to baseline level after 1 year. T2 measurement can be a useful tool for quantitative evaluation of postoperative cartilage changes compared to conventional MRI. • T2 mapping provides objective data for longitudinal monitoring following surgery. • Increased cartilage T2 values post-MAT returned to baseline in one year. • Further studies are required to predict the chondroprotective effect of MAT.

  12. Flow Distribution Measurement Feasibility in Supercritical CO 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lance, Blake

    2017-12-01

    Supercritical CO 2 (sCO 2) is a fluid of interest for advanced power cycles that can reach thermal to electric energy conversion efficiencies of 50% or higher. Of particular interest for fossil-fired natural gas is the Allam cycle that captures nearly all CO 2 emissions and exports it as a fluid stream where it may be of value. The combustion process conditions are unlike any before realized with 90-95% CO 2 concentration, temperatures around 1000°C, and pressures near 300 bar. This work outlines the experimental feasibility of flow measurements to acquire the first known data in pure sCO 2 atmore » similar but reduced temperature and pressure conditions.« less

  13. Different top-down approaches to estimate measurement uncertainty of whole blood tacrolimus mass concentration values.

    PubMed

    Rigo-Bonnin, Raül; Blanco-Font, Aurora; Canalias, Francesca

    2018-05-08

    Values of mass concentration of tacrolimus in whole blood are commonly used by the clinicians for monitoring the status of a transplant patient and for checking whether the administered dose of tacrolimus is effective. So, clinical laboratories must provide results as accurately as possible. Measurement uncertainty can allow ensuring reliability of these results. The aim of this study was to estimate measurement uncertainty of whole blood mass concentration tacrolimus values obtained by UHPLC-MS/MS using two top-down approaches: the single laboratory validation approach and the proficiency testing approach. For the single laboratory validation approach, we estimated the uncertainties associated to the intermediate imprecision (using long-term internal quality control data) and the bias (utilizing a certified reference material). Next, we combined them together with the uncertainties related to the calibrators-assigned values to obtain a combined uncertainty for, finally, to calculate the expanded uncertainty. For the proficiency testing approach, the uncertainty was estimated in a similar way that the single laboratory validation approach but considering data from internal and external quality control schemes to estimate the uncertainty related to the bias. The estimated expanded uncertainty for single laboratory validation, proficiency testing using internal and external quality control schemes were 11.8%, 13.2%, and 13.0%, respectively. After performing the two top-down approaches, we observed that their uncertainty results were quite similar. This fact would confirm that either two approaches could be used to estimate the measurement uncertainty of whole blood mass concentration tacrolimus values in clinical laboratories. Copyright © 2018 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  14. Lidar Measurements of Atmospheric CO2 From Regional to Global Scales

    NASA Technical Reports Server (NTRS)

    Lin, Bing; Harrison, F. Wallace; Nehrir, Amin; Browell, Edward; Dobler, Jeremy; Campbell, Joel; Meadows, Byron; Obland, Michael; Ismail, Syed; Kooi, Susan; hide

    2015-01-01

    Atmospheric CO2 is a critical forcing for the Earth's climate and the knowledge on its distributions and variations influences predictions of the Earth's future climate. Large uncertainties in the predictions persist due to limited observations. This study uses the airborne Intensity-Modulated Continuous-Wave (IMCW) lidar developed at NASA Langley Research Center to measure regional atmospheric CO2 spatio-temporal variations. Further lidar development and demonstration will provide the capability of global atmospheric CO2 estimations from space, which will significantly advances our knowledge on atmospheric CO2 and reduce the uncertainties in the predictions of future climate. In this presentation, atmospheric CO2 column measurements from airborne flight campaigns and lidar system simulations for space missions will be discussed. A measurement precision of approx.0.3 ppmv for a 10-s average over desert and vegetated surfaces has been achieved. Data analysis also shows that airborne lidar CO2 column measurements over these surfaces agree well with in-situ measurements. Even when thin cirrus clouds present, consistent CO2 column measurements between clear and thin cirrus cloudy skies are obtained. Airborne flight campaigns have demonstrated that precise atmospheric column CO2 values can be measured from current IM-CW lidar systems, which will lead to use this airborne technique in monitoring CO2 sinks and sources in regional and continental scales as proposed by the NASA Atmospheric Carbon and Transport â€" America project. Furthermore, analyses of space CO2 measurements shows that applying the current IM-CW lidar technology and approach to space, the CO2 science goals of space missions will be achieved, and uncertainties in CO2 distributions and variations will be reduced.

  15. Resolving Some Issues in Using Value-Added Measures of Productivity for School and Teacher Incentives: Ideas from Technical Assistance and TIF Grantee Experience. The Harvesting Project

    ERIC Educational Resources Information Center

    Milanowski, Anthony

    2011-01-01

    Although many researchers and policy analysts (e.g., Harris, Glazerman et al., 2011; 2010) consider value-added to be the state of the art in school and teacher productivity measurement, only a minority of Teacher Incentive Fund (TIF) Round 1 and 2 grantees used value-added as a measure of school or teacher performance. Fourteen of the 34 grantees…

  16. How should novelty be valued in science?

    PubMed

    Cohen, Barak A

    2017-07-25

    Scientists are under increasing pressure to do "novel" research. Here I explore whether there are risks to overemphasizing novelty when deciding what constitutes good science. I review studies from the philosophy of science to help understand how important an explicit emphasis on novelty might be for scientific progress. I also review studies from the sociology of science to anticipate how emphasizing novelty might impact the structure and function of the scientific community. I conclude that placing too much value on novelty could have counterproductive effects on both the rate of progress in science and the organization of the scientific community. I finish by recommending that our current emphasis on novelty be replaced by a renewed emphasis on predictive power as a characteristic of good science.

  17. Can and should value-based pricing be applied to molecular diagnostics?

    PubMed

    Garau, Martina; Towse, Adrian; Garrison, Louis; Housman, Laura; Ossa, Diego

    2013-01-01

    Current pricing and reimbursement systems for diagnostics are not efficient. Prices for diagnostics are often driven by administrative practices and expected production cost. The purpose of the paper is to discuss how a value-based pricing framework being used to ensure efficient use and price of medicines could also be applied to diagnostics. Diagnostics not only facilitates health gain and cost savings, but also information to guide patients' decisions on interventions and their future 'behaviors'. For value assessment processes we recommend a two-part approach. Companion diagnostics introduced at the launch of the drug should be assessed through new drug assessment processes considering a broad range of value elements and a balanced analysis of diagnostic impacts. A separate diagnostic-dedicated committee using value-based pricing principles should review other diagnostics lying outside the companion diagnostics-and-drug 'at-launch' situation.

  18. Comparison of cerebral vascular reactivity measures obtained using breath-holding and CO2 inhalation

    PubMed Central

    Tancredi, Felipe B; Hoge, Richard D

    2013-01-01

    Stimulation of cerebral vasculature using hypercapnia has been widely used to study cerebral vascular reactivity (CVR), which can be expressed as the quantitative change in cerebral blood flow (CBF) per mm Hg change in end-tidal partial pressure of CO2 (PETCO2). We investigate whether different respiratory manipulations, with arterial spin labeling used to measure CBF, lead to consistent measures of CVR. The approaches included: (1) an automated system delivering variable concentrations of inspired CO2 for prospective targeting of PETCO2, (2) administration of a fixed concentration of CO2 leading to subject-dependent changes in PETCO2, (3) a breath-hold (BH) paradigm with physiologic modeling of CO2 accumulation, and (4) a maneuver combining breath-hold and hyperventilation. When CVR was expressed as the percent change in CBF per mm Hg change in PETCO2, methods 1 to 3 gave consistent results. The CVR values using method 4 were significantly lower. When CVR was expressed in terms of the absolute change in CBF (mL/100 g per minute per mm Hg), greater discrepancies became apparent: methods 2 and 3 gave lower absolute CVR values compared with method 1, and the value obtained with method 4 was dramatically lower. Our findings indicate that care must be taken to ensure that CVR is measured over the linear range of the CBF-CO2 dose–response curve, avoiding hypocapnic conditions. PMID:23571282

  19. The Role of Patient-Reported Outcome Measures in Value-Based Payment Reform.

    PubMed

    Squitieri, Lee; Bozic, Kevin J; Pusic, Andrea L

    2017-06-01

    The U.S. health care system is currently experiencing profound change. Pressure to improve the quality of patient care and control costs have caused a rapid shift from traditional volume-driven fee-for-service reimbursement to value-based payment models. Under the 2015 Medicare Access and Children's Health Insurance Program Reauthorization Act, providers will be evaluated on the basis of quality and cost efficiency and ultimately receive adjusted reimbursement as per their performance. Although current performance metrics do not incorporate patient-reported outcome measures (PROMs), many wonder whether and how PROMs will eventually fit into value-based payment reform. On November 17, 2016, the second annual Patient-Reported Outcomes in Healthcare Conference brought together international stakeholders across all health care disciplines to discuss the potential role of PROs in value-based health care reform. The purpose of this article was to summarize the findings from this conference in the context of recent literature and guidelines to inform implementation of PROs in value-based payment models. Recommendations for evaluating key perspectives and measurement goals are made to facilitate appropriate use of PROMs to best benefit and amplify the voice of our patients. Copyright © 2017 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  20. Critical micelle concentration values for different surfactants measured with solid-phase microextraction fibers.

    PubMed

    Haftka, Joris J-H; Scherpenisse, Peter; Oetter, Günter; Hodges, Geoff; Eadsforth, Charles V; Kotthoff, Matthias; Hermens, Joop L M

    2016-09-01

    The amphiphilic nature of surfactants drives the formation of micelles at the critical micelle concentration (CMC). Solid-phase microextraction (SPME) fibers were used in the present study to measure CMC values of 12 nonionic, anionic, cationic, and zwitterionic surfactants. The SPME-derived CMC values were compared to values determined using a traditional surface tension method. At the CMC of a surfactant, a break in the relationship between the concentration in SPME fibers and the concentration in water is observed. The CMC values determined with SPME fibers deviated by less than a factor of 3 from values determined with a surface tension method for 7 out of 12 compounds. In addition, the fiber-water sorption isotherms gave information about the sorption mechanism to polyacrylate-coated SPME fibers. A limitation of the SPME method is that CMCs for very hydrophobic cationic surfactants cannot be determined when the cation exchange capacity of the SPME fibers is lower than the CMC value. The advantage of the SPME method over other methods is that CMC values of individual compounds in a mixture can be determined with this method. However, CMC values may be affected by the presence of compounds with other chain lengths in the mixture because of possible mixed micelle formation. Environ Toxicol Chem 2016;35:2173-2181. © 2016 SETAC. © 2016 SETAC.

  1. Carr-Purcell-Meiboom-Gill imaging of prostate cancer: quantitative T2 values for cancer discrimination.

    PubMed

    Roebuck, Joseph R; Haker, Steven J; Mitsouras, Dimitris; Rybicki, Frank J; Tempany, Clare M; Mulkern, Robert V

    2009-05-01

    Quantitative, apparent T(2) values of suspected prostate cancer and healthy peripheral zone tissue in men with prostate cancer were measured using a Carr-Purcell-Meiboom-Gill (CPMG) imaging sequence in order to assess the cancer discrimination potential of tissue T(2) values. The CPMG imaging sequence was used to image the prostates of 18 men with biopsy-proven prostate cancer. Whole gland coverage with nominal voxel volumes of 0.54 x 1.1 x 4 mm(3) was obtained in 10.7 min, resulting in data sets suitable for generating high-quality images with variable T(2)-weighting and for evaluating quantitative T(2) values on a pixel-by-pixel basis. Region-of-interest analysis of suspected healthy peripheral zone tissue and suspected cancer, identified on the basis of both T(1)- and T(2)-weighted signal intensities and available histopathology reports, yielded significantly (P<.0001) longer apparent T(2) values in suspected healthy tissue (193+/-49 ms) vs. suspected cancer (100+/-26 ms), suggesting potential utility of this method as a tissue specific discrimination index for prostate cancer. We conclude that CPMG imaging of the prostate can be performed in reasonable scan times and can provide advantages over T(2)-weighted fast spin echo (FSE) imaging alone, including quantitative T(2) values for cancer discrimination as well as proton density maps without the point spread function degradation associated with short effective echo time FSE sequences.

  2. Quality measures and pediatric radiology: suggestions for the transition to value-based payment.

    PubMed

    Heller, Richard E; Coley, Brian D; Simoneaux, Stephen F; Podberesky, Daniel J; Hernanz-Schulman, Marta; Robertson, Richard L; Donnelly, Lane F

    2017-06-01

    Recent political and economic factors have contributed to a meaningful change in the way that quality in health care, and by extension value, are viewed. While quality is often evaluated on the basis of subjective criteria, pay-for-performance programs that link reimbursement to various measures of quality require use of objective and quantifiable measures. This evolution to value-based payment was accelerated by the 2015 passage of the Medicare Access and CHIP (Children's Health Insurance Program) Reauthorization Act (MACRA). While many of the drivers of these changes are rooted in federal policy and programs such as Medicare and aimed at adult patients, the practice of pediatrics and pediatric radiology will be increasingly impacted. This article addresses issues related to the use of quantitative measures to evaluate the quality of services provided by the pediatric radiology department or sub-specialty section, particularly as seen from the viewpoint of a payer that may be considering ways to link payment to performance. The paper concludes by suggesting a metric categorization strategy to frame future work on the subject.

  3. Developing a Measure to Assess Emotions Associated with Never Being Deployed.

    PubMed

    Hoopsick, Rachel A; Homish, D Lynn; Bartone, Paul T; Homish, Gregory G

    2018-03-14

    Much research has focused on stress related to deployments; however, a substantial proportion of soldiers never deploy. In a study of 1.3 million veterans, suicide risk was higher among veterans who had never deployed. Thus, not being deployed may have an impact on soldiers' well-being; however, no measures exist to assess emotions regarding non-deployment. We aimed to develop and test an original measure of non-deployment emotions. We examined the Non-Deployment Emotions (NDE) questionnaire, a novel four-item measure of guilt, unit value, unit camaraderie, and unit connectedness in a sample of never-deployed male and female US Army Reserve/National Guard (USAR/NG) soldiers (N = 174). Data are from Operation: SAFETY (Soldiers and Families Excelling Through the Years), an ongoing survey-based study examining the health of USAR/NG soldiers and their partners. The protocol was approved by the Institutional Review Board at the State University of New York at Buffalo. The relationship between each of the items was examined by calculating correlation and alpha coefficients. Latent class analyses tested for the existence of distinct levels of negative emotions related to non-deployment. Negative binomial regression models examined the cross-sectional associations between NDE summary score and each of the following outcomes, separately: anger, anxiety, depression, and post-traumatic stress. More than half of never-deployed USAR/NG soldiers expressed negative emotions for having not been deployed. "Guilt," "value," "camaraderie," and "connectedness" were each positively correlated with each other (p < 0.001) and the internal consistency reliability was high (male soldier α = 0.90, female soldier α = 0.93). Latent class analyses revealed a superior three-class model with well-delineated class membership (entropy = 0.93): "Class 1" (low NDE; 47.6%), "Class 2" (moderate NDE; 33.8%), and "Class 3" (high NDE; 18.6%). Regression models demonstrated that greater non

  4. Comparison of oxygen saturation values and measurement times by pulse oximetry in various parts of the body.

    PubMed

    Yönt, Gülendam Hakverdioğlu; Korhan, Esra Akin; Khorshid, Leyla

    2011-11-01

    The aim of this study, which included 40 patients, was to compare the values pulse oximetry and the measurement times in various regions of the body. Data were analyzed using intraclass correlation coefficient test and paired-sample test. The confidence power value was found to be .81 for the comparison of oxygen saturation values by arterial blood gas analysis and measurement by the forehead probe. It was found that the time for oxygen saturation measurement using the forehead probe was shorter than those using the finger and toe probes. Copyright © 2011 Elsevier Inc. All rights reserved.

  5. Quality, Safety, Value: From Theory to Practice Management What Should We Measure?

    PubMed

    Shore, Benjamin J; Murphy, Robert F; Hogue, Grant D

    2015-01-01

    Over the past 35 years the health care community and in particular orthopaedic surgery, has undergone a transformation from retrospective case-series-based expert opinion to randomized prospective clinical trials. During this transition, orthopaedic surgeons have become very skilled in the measurement of physician-derived outcomes (radiographic angles, complications, recurrences, and mortality); however, these are not patient-centered outcomes and they are of little importance to our patients' satisfaction. Moving forward outcome measurement needs to be restructured to focus more on patient-reported outcomes. This paper outlines why outcome measurement is important, reviews outcome strategies that have been used historically, introduces a new outcome measurement tool and identifies strategies for future implementation and measurement of health care quality and value within pediatric orthopaedics.

  6. Effect of sampling location on L* values and pH measurements and their relationship in broiler breast fillets

    USDA-ARS?s Scientific Manuscript database

    Lightness (CIELAB L*) and pH values are the most widely measured quality indicators for broiler breast fillets (pectoralis major). Measurement of L* values with a spectrophotometer can be done through Specular Component Included (SCI) or Specular Component Excluded (SCE) modes. The intra-fillet loca...

  7. Comparison of Interstitial Fluid pH, PCO2, PO2 with Venous Blood Values During Repetitive Handgrip Exercise

    NASA Technical Reports Server (NTRS)

    Hagan, Ronald Donald; Soller, Babs R.; Shear, Michael; Walz, Matthias; Landry, Michelle; Heard, Stephen

    2006-01-01

    We evaluated the use of a small, fiber optic sensor to measure pH, PCO2 and PO2 from forearm muscle interstitial fluid (IF) during handgrip dynamometry. PURPOSE: Compare pH, PCO2 and PO2 values obtained from venous blood with those from the IF of the flexor digitorum superficialis (FDS) during three levels of exercise intensity. METHODS: Six subjects (5M/1F), average age 29+/-5 yrs, participated in the study. A venous catheter was placed in the retrograde direction in the antecubital space and a fiber optic sensor (Paratrend, Diametrics Medical, Inc.) was placed through a 22 G catheter into the FDS muscle under ultrasound guidance. After a 45 min rest period, subjects performed three 5-min bouts of repetitive handgrip exercise (2s contraction/1 s relaxation) at attempted levels of 15%, 30% and 45% of maximal voluntary contraction. The order of the exercise bouts was random with the second and third bouts started after blood lactate had returned to baseline. Venous blood was sampled every minute during exercise and analyzed with an I-Stat CG-4+ cartridge, while IF fiber optic sensor measurements were obtained every 2 s. Change from pre-exercise baseline to end of exercise was computed for pH, PCO2 and PO2. Blood and IF values were compared with a paired t-test. RESULTS: Baseline values for pH, PCO2 and PO2 were 7.37+/-0.02, 46+/-4 mm Hg, and 36+/-6 mm Hg respectively in blood and 7.39+/-0.02, 44+/-6 mm Hg, and 35+/-14 mm Hg in IF. Average changes over all exercise levels are noted in the Table below. For each parameter the exercise-induced change was at least twice as great in IF as in blood. In blood and IF, pH and PCO2 increases were directly related to exercise intensity. Change in venous PO2 was unrelated to exercise intensity, while IF PO2 decreased with increases in exercise intensity. CONCLUSIONS: Measurement of IF pH, PCO2 and PO2 is more sensitive to exercise intensity than measurement of the same parameters in venous blood and provides continuous

  8. Integration of moral values during L2 sentence processing.

    PubMed

    Foucart, Alice; Moreno, Eva; Martin, Clara D; Costa, Albert

    2015-11-01

    This study reports an event-related potential (ERP) experiment examining whether valuation (i.e., one's own values) is integrated incrementally and whether it affects L2 speakers' online interpretation of the sentence. We presented Spanish native speakers and French-Spanish mid-proficiency late L2 speakers with visual sentences containing value-consistent and value-inconsistent statements (e.g., 'Nowadays, paedophilia should be prohibited/tolerated across the world.'). Participants' brain activity was recorded as they were reading the sentences and indicating whether they agreed with the statements or not. Behaviourally, the two groups revealed identical valuation. The ERP analyses showed both a semantic (N400) and an affect-related response (LPP) to value-inconsistent statements in the native group, but only an LPP in the non-native group. These results suggest that valuation is integrated online (presence of LPP) during L2 sentence comprehension but that it does not interfere with semantic processing (absence of N400).

  9. New measurements of W-values for protons and alpha particles.

    PubMed

    Giesen, U; Beck, J

    2014-10-01

    The increasing importance of ion beams in cancer therapy and the lack of experimental data for W-values for protons and heavy ions in air require new measurements. A new experimental set-up was developed at PTB and consistent measurements of W-values in argon, nitrogen and air for protons and alpha particles with energies from 0.7 to 3.5 MeV u(-1) at PTB, and for carbon ions between 3.6 and 7.0 MeV u(-1) at GSI were carried out. This publication concentrates on the measurements with protons and alpha particles at PTB. The experimental methods and the determination of corrections for recombination effects, beam-induced background radiation and additional effects are presented. © The Author 2013. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  10. Measuring the nose in septorhinoplasty patients: ultrasonographic standard values and clinical correlations.

    PubMed

    Stenner, Markus; Koopmann, Mario; Rudack, Claudia

    2017-02-01

    Although septorhinoplasty is the most commonly performed operation in plastic surgery, and the surgical plan as well as its outcome is directly related to the configuration of the anatomical structures in the nose, these are not routinely assessed preoperatively. The aim of our study was to evaluate the nasal soft tissue and cartilaginous structures by means of high-resolution ultrasonography to set up clinical correlations and standard values. We examined 44 patients before septorhinoplasty by high-resolution ultrasonography in noncontact mode. All pictures were quantitatively evaluated by measuring 13 lengths and 4 ratios. All patients underwent a rhinomanometry measuring the nasal air flow. Besides others, men as well as older patients have a significantly thicker alar cartilage. Patients with thinner alar cartilages have a significantly smaller interdomal distance as well as significantly thinner upper lateral cartilages. The soft tissue above the bony dorsum was significantly thicker in older patients. Younger patients have significantly thicker soft tissue in relation to their cartilage. Patients with thicker soft tissue and thinner cartilage have a smaller tip. The interdomal distance and the thickness of the cartilaginous septum significantly correlated with the nasal air flow. We set up standard values of nasal structures in septorhinoplasty patients which can be used as reference values. By judging cartilage and soft tissue characteristics preoperatively, relevant factors for distinct procedures could be analyzed and the surgical steps can be better planned. Visualization by ultrasonography enables the surgeon to achieve treatment goals in a more predictable fashion.

  11. Prognostic and diagnostic value of EEG signal coupling measures in coma.

    PubMed

    Zubler, Frederic; Koenig, Christa; Steimer, Andreas; Jakob, Stephan M; Schindler, Kaspar A; Gast, Heidemarie

    2016-08-01

    Our aim was to assess the diagnostic and predictive value of several quantitative EEG (qEEG) analysis methods in comatose patients. In 79 patients, coupling between EEG signals on the left-right (inter-hemispheric) axis and on the anterior-posterior (intra-hemispheric) axis was measured with four synchronization measures: relative delta power asymmetry, cross-correlation, symbolic mutual information and transfer entropy directionality. Results were compared with etiology of coma and clinical outcome. Using cross-validation, the predictive value of measure combinations was assessed with a Bayes classifier with mixture of Gaussians. Five of eight measures showed a statistically significant difference between patients grouped according to outcome; one measure revealed differences in patients grouped according to the etiology. Interestingly, a high level of synchrony between the left and right hemisphere was associated with mortality on intensive care unit, whereas higher synchrony between anterior and posterior brain regions was associated with survival. The combination with the best predictive value reached an area-under the curve of 0.875 (for patients with post anoxic encephalopathy: 0.946). EEG synchronization measures can contribute to clinical assessment, and provide new approaches for understanding the pathophysiology of coma. Prognostication in coma remains a challenging task. qEEG could improve current multi-modal approaches. Copyright © 2015 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  12. The value of body weight measurement to assess dehydration in children.

    PubMed

    Pruvost, Isabelle; Dubos, François; Chazard, Emmanuel; Hue, Valérie; Duhamel, Alain; Martinot, Alain

    2013-01-01

    Dehydration secondary to gastroenteritis is one of the most common reasons for office visits and hospital admissions. The indicator most commonly used to estimate dehydration status is acute weight loss. Post-illness weight gain is considered as the gold-standard to determine the true level of dehydration and is widely used to estimate weight loss in research. To determine the value of post-illness weight gain as a gold standard for acute dehydration, we conducted a prospective cohort study in which 293 children, aged 1 month to 2 years, with acute diarrhea were followed for 7 days during a 3-year period. The main outcome measures were an accurate pre-illness weight (if available within 8 days before the diarrhea), post-illness weight, and theoretical weight (predicted from the child's individual growth chart). Post-illness weight was measured for 231 (79%) and both theoretical and post-illness weights were obtained for 111 (39%). Only 62 (21%) had an accurate pre-illness weight. The correlation between post-illness and theoretical weight was excellent (0.978), but bootstrapped linear regression analysis showed that post-illness weight underestimated theoretical weight by 0.48 kg (95% CI: 0.06-0.79, p<0.02). The mean difference in the fluid deficit calculated was 4.0% of body weight (95% CI: 3.2-4.7, p<0.0001). Theoretical weight overestimated accurate pre-illness weight by 0.21 kg (95% CI: 0.08-0.34, p = 0.002). Post-illness weight underestimated pre-illness weight by 0.19 kg (95% CI: 0.03-0.36, p = 0.02). The prevalence of 5% dehydration according to post-illness weight (21%) was significantly lower than the prevalence estimated by either theoretical weight (60%) or clinical assessment (66%, p<0.0001).These data suggest that post-illness weight is of little value as a gold standard to determine the true level of dehydration. The performance of dehydration signs or scales determined by using post-illness weight as a gold standard has to be reconsidered.

  13. Measurement of utility values in the UK for health states related to immune thrombocytopenic purpura.

    PubMed

    Szende, Agota; Brazier, John; Schaefer, Caroline; Deuson, Robert; Isitt, John J; Vyas, Paresh

    2010-08-01

    To measure utility values associated with immune (idiopathic) thrombocytopenic purpura (ITP), as perceived by the United Kingdom (UK) general public. A multi-step process, including clinical trial data, literature review, and patient focus group, was used to develop ITP health states valued in a web survey. Six ITP health states were defined based on platelet levels, risk of bleeding and key adverse events/disease complications. Clinical trial data on bleeding and ITP-specific quality of life data were key sources for developing health-state descriptions. 359 respondents, randomly selected from a managed web panel in the UK, completed the web-based Time Trade-Off survey. Wilcoxon signed-rank test was used to compare differences between each pair of health states. Sample characteristics (mean age: 47.9 +/- 16.9 years; 54% female) were comparable to the UK general population. ITP health states were valued as significantly worse than perfect health. Experiencing bleeding episodes was a more important driver than low platelet levels in valuing a health state to be worse. Substantial disutilities were associated with surviving an intracranial haemorrhage. Mean (SD) utility values for each ITP health state are: HS1: platelets >or=50 x 10(9)/L, no outpatient bleed: 0.863 +/- 0.15; HS2: platelets >or=50 x 10(9)/L, outpatient bleed: 0.734 +/- 0.19; HS3: platelets <50 x 10(9)/L, no outpatient bleed: 0.841 +/- 0.19; HS4: platelets <50 x 10(9)/L, outpatient bleed: 0.732 +/- 0.19; HS5: intracranial haemorrhage (2-6 months): 0.038 +/- 0.46; HS6: steroid treatment adverse events: 0.758 +/- 0.20. Potential limitations relate to web user population characteristics and lack of comparative testing of web-based TTO methods. Results provide evidence that the UK general population associate substantial loss of value living with ITP, suggesting an important role for new ITP treatments. Utility values based on these health states may be useful in future cost-effectiveness studies of

  14. Half-life, branching-ratio, and Q-value measurement for the superallowed 0{sup +}{yields}0{sup +}{beta}{sup +} emitter {sup 42}Ti

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nieto, T. Kurtukian; Souin, J.; Audirac, L.

    2009-09-15

    The half-life, the branching ratio, and the decay Q value of the superallowed {beta} emitter {sup 42}Ti were measured in an experiment performed at the JYFLTRAP facility of the Accelerator Laboratory of the University of Jyvaeskylae. {sup 42}Ti is the heaviest T{sub z}=-1 nucleus for which high-precision measurements of these quantities have been tried. The half-life (T{sub 1/2}=208.14{+-}0.45 ms) and the Q value [Q{sub EC}=7016.83(25) keV] are close to or reach the required precision of about 0.1%. The branching ratio for the superallowed decay branch [BR=47.7(12)%], a by-product of the half-life measurement, does not reach the necessary precision yet. Nonetheless,more » these results allow one to determine the experimental ft value and the corrected Ft value to be 3114(79) and 3122(79) s, respectively.« less

  15. High-precision optical measurement of the 2S hyperfine interval in atomic hydrogen.

    PubMed

    Kolachevsky, N; Fischer, M; Karshenboim, S G; Hänsch, T W

    2004-01-23

    We have applied an optical method to the measurement of the 2S hyperfine interval in atomic hydrogen. The interval has been measured by means of two-photon spectroscopy of the 1S-2S transition on a hydrogen atomic beam shielded from external magnetic fields. The measured value of the 2S hyperfine interval is equal to 177 556 860(16) Hz and represents the most precise measurement of this interval to date. The theoretical evaluation of the specific combination of 1S and 2S hyperfine intervals D21 is in fair agreement (within 1.4 sigma) with the value for D21 deduced from our measurement.

  16. Method for high-accuracy reflectance measurements in the 2.5-microm region.

    PubMed

    Richter, Rudolf; Müller, Andreas

    2003-02-20

    Reflectance measurement with spectroradiometers in the solar wavelength region (0.4-2.5 microm) are frequently conducted in the laboratory or in the field to characterize surface materials of artificial and natural targets. The spectral surface reflectance is calculated as the ratio of the signals obtained over the target surface and a reference panel, yielding a relative reflectance value. If the reflectance of the reference panel is known, the absolute target reflectance can be computed. This standard measurement technique assumes that the signal at the radiometer is due completely to reflected target and reference radiation. However, for field measurements in the 2.4-2.5-microm region with the Sun as the illumination source, the emitted thermal radiation is not a negligible part of the signal even at ambient temperatures, because the atmospheric transmittance, and thus the solar illumination level, is small in the atmospheric absorption regions. A new method is proposed that calculates reflectance values in the 2.4-2.5-microm region while it accounts for the reference panel reflectance and the emitted radiation. This technique needs instruments with noise-equivalent radiances of 2 orders of magnitude below currently commercially available instruments and requires measurement of the surface temperatures of target and reference. If the reference panel reflectance and temperature effects are neglected, the standard method yields reflectance errors up to 0.08 and 0.15 units for 7- and 2-nm bandwidth instruments, respectively. For the new method the corresponding errors can be reduced to approximately 0.01 units for the surface temperature range of 20-35 degrees C.

  17. Why social values cannot be changed for the sake of conservation

    USGS Publications Warehouse

    Manfredo, Michael J.; Bruskotter, Jeremy T.; Teel, Tara L.; Fulton, David C.; Schwartz, Shalom H.; Arlinghaus, Robert; Oishi, Shigehiro; Uskul, Ayse K.; Redford, Kent; Kitayama, Shinobu; Sullivan, Leeann

    2017-01-01

    The hope for creating widespread change in social values has endured among conservation professionals since early calls by Aldo Leopold for a “land ethic.” However, there has been little serious attention in conservation to the fields of investigation that address values, how they are formed, and how they change. We introduce a social–ecological systems conceptual approach in which values are seen not only as motivational goals people hold but also as ideas that are deeply embedded in society's material culture, collective behaviors, traditions, and institutions. Values define and bind groups, organizations, and societies; serve an adaptive role; and are typically stable across generations. When abrupt value changes occur, they are in response to substantial alterations in the social–ecological context. Such changes build on prior value structures and do not result in complete replacement. Given this understanding of values, we conclude that deliberate efforts to orchestrate value shifts for conservation are unlikely to be effective. Instead, there is an urgent need for research on values with a multilevel and dynamic view that can inform innovative conservation strategies for working within existing value structures. New directions facilitated by a systems approach will enhance understanding of the role values play in shaping conservation challenges and improve management of the human component of conservation.

  18. Patient value: its nature, measurement, and role in real world evidence studies and outcomes-based reimbursement.

    PubMed

    McKenna, Stephen P; Wilburn, Jeanette

    2018-05-01

    The assessment of "patient value" is fundamental to clinical trials, real world evidence studies, and outcomes-based reimbursement schemes. Measures of health-related quality-of-life (HRQoL) are widely used in health research. Such measures are effective in determining the presence or absence of symptoms and functional ability. However, HRQoL measures were not intended, nor designed, to determine the value to patients of alternative health states. Functions have no intrinsic value-they are a means to fulfil human needs. However, needs can be met in a variety of ways, for example by adopting different functions or by the provision of social services. It is possible to analyze all functions in terms of the needs they satisfy. A needs model has been applied in health research since the 1990s. It is concerned with the extent to which human needs are fulfilled in the presence of disease and its treatment. It is argued that this is the major concern of the patient. Needs-based measures are patient-centric and produce a valid unidimensional index of outcome. Consequently, they provide a direct means of measuring patient value. This approach provides the possibility of evaluating health services in terms of the value they provide to consumers and payers. It also has a role to play in real-world evidence studies and outcomes-based reimbursement. It is recommended that greater attention is given in future to the development of patient-reported outcome measures that provide direct assessments of patient value.

  19. Minimal sufficient positive-operator valued measure on a separable Hilbert space

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kuramochi, Yui, E-mail: kuramochi.yui.22c@st.kyoto-u.ac.jp

    We introduce a concept of a minimal sufficient positive-operator valued measure (POVM), which is the least redundant POVM among the POVMs that have the equivalent information about the measured quantum system. Assuming the system Hilbert space to be separable, we show that for a given POVM, a sufficient statistic called a Lehmann-Scheffé-Bahadur statistic induces a minimal sufficient POVM. We also show that every POVM has an equivalent minimal sufficient POVM and that such a minimal sufficient POVM is unique up to relabeling neglecting null sets. We apply these results to discrete POVMs and information conservation conditions proposed by the author.

  20. Reporting the national antimicrobial consumption in Danish pigs: influence of assigned daily dosage values and population measurement.

    PubMed

    Dupont, Nana; Fertner, Mette; Kristensen, Charlotte Sonne; Toft, Nils; Stege, Helle

    2016-05-03

    Transparent calculation methods are crucial when investigating trends in antimicrobial consumption over time and between populations. Until 2011, one single standardized method was applied when quantifying the Danish pig antimicrobial consumption with the unit "Animal Daily Dose" (ADD). However, two new methods for assigning values for ADDs have recently emerged, one implemented by DANMAP, responsible for publishing annual reports on antimicrobial consumption, and one by the Danish Veterinary and Food Administration (DVFA), responsible for the Yellow Card initiative. In addition to new ADD assignment methods, Denmark has also experienced a shift in the production pattern, towards a larger export of live pigs. The aims of this paper were to (1) describe previous and current ADD assignment methods used by the major Danish institutions and (2) to illustrate how ADD assignment method and choice of population and population measurement affect the calculated national antimicrobial consumption in pigs (2007-2013). The old VetStat ADD-values were based on SPCs in contrast to the new ADD-values, which were based on active compound, concentration and administration route. The new ADD-values stated by both DANMAP and DVFA were only identical for 48 % of antimicrobial products approved for use in pigs. From 2007 to 2013, the total number of ADDs per year increased by 9 % when using the new DVFA ADD-values, but decreased by 2 and 7 % when using the new DANMAP ADD-values or the old VetStat ADD-values, respectively. Through 2007 to 2013, the production of pigs increased from 26.1 million pigs per year with 18 % exported live to 28.7 million with 34 % exported live. In the same time span, the annual pig antimicrobial consumption increased by 22.2 %, when calculated using the new DVFA ADD-values and pigs slaughtered per year as population measurement (13.0 ADDs/pig/year to 15.9 ADDs/pig/year). However, when based on the old VetStat ADD values and pigs produced per year

  1. Towards absolute laser spectroscopic CO2 isotope ratio measurements

    NASA Astrophysics Data System (ADS)

    Anyangwe Nwaboh, Javis; Werhahn, Olav; Ebert, Volker

    2017-04-01

    Knowledge of isotope composition of carbon dioxide (CO2) in the atmosphere is necessary to identify sources and sinks of this key greenhouse gas. In the last years, laser spectroscopic techniques such as cavity ring-down spectroscopy (CRDS) and tunable diode laser absorption spectroscopy (TDLAS) have been shown to perform accurate isotope ratio measurements for CO2 and other gases like water vapour (H2O) [1,2]. Typically, isotope ratios are reported in literature referring to reference materials provided by e.g. the International Atomic Energy Agency (IAEA). However, there could be some benefit if field deployable absolute isotope ratio measurement methods were developed to address issues such as exhausted reference material like the Pee Dee Belemnite (PDB) standard. Absolute isotope ratio measurements would be particularly important for situations where reference materials do not even exist. Here, we present CRDS and TDLAS-based absolute isotope ratios (13C/12C ) in atmospheric CO2. We demonstrate the capabilities of the used methods by measuring CO2 isotope ratios in gas standards. We compare our results to values reported for the isotope certified gas standards. Guide to the expression of uncertainty in measurement (GUM) compliant uncertainty budgets on the CRDS and TDLAS absolute isotope ratio measurements are presented, and traceability is addressed. We outline the current impediments in realizing high accuracy absolute isotope ratio measurements using laser spectroscopic methods, propose solutions and the way forward. Acknowledgement Parts of this work have been carried out within the European Metrology Research Programme (EMRP) ENV52 project-HIGHGAS. The EMRP is jointly funded by the EMRP participating countries within EURAMET and the European Union. References [1] B. Kühnreich, S. Wagner, J. C. Habig,·O. Möhler, H. Saathoff, V. Ebert, Appl. Phys. B 119:177-187 (2015). [2] E. Kerstel, L. Gianfrani, Appl. Phys. B 92, 439-449 (2008).

  2. Measuring Nitrous Oxide Mass Transfer into Non-Aqueous CO2BOL CO2 Capture Solvents

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Whyatt, Greg A.; Freeman, Charles J.; Zwoster, Andy

    2016-03-28

    This paper investigates CO2 absorption behavior in CO2BOL solvents by decoupling the physical and chemical effects using N2O as a non-reactive mimic. Absorption measurements were performed using a wetted-wall contactor. Testing was performed using a “first generation” CO2 binding organic liquid (CO2BOL), comprised of an independent base and alcohol. Measurements were made with N2O at a lean (0.06 mol CO2/mol BOL) and rich (0.26 mol CO2/mol BOL) loading, each at three temperatures (35, 45 and 55 °C). Liquid-film mass transfer coefficients (kg') were calculated by subtracting the gas film resistance – determined from a correlation from literature – from themore » overall mass transfer measurement. The resulting kg' values for N2O in CO2BOLs were found to be higher than that of 5 M aqueous MEA under comparable conditions, which is supported by published measurements of Henry’s coefficients for N2O in various solvents. These results suggest that the physical solubility contribution for CO2 absorption in CO2BOLs is greater than that of aqueous amines, an effect that may pertain to other non-aqueous solvents.« less

  3. Using the New Postacute Care Quality Measures to Demonstrate the Value of Occupational Therapy.

    PubMed

    Sandhu, Sharmila; Furniss, Jeremy; Metzler, Christina

    As the health care system continues to evolve toward one based on quality not quantity, demonstrating the value of occupational therapy has never been more important. Providing high-quality services, achieving optimal outcomes, and identifying and promoting occupational therapy's distinct value are the responsibilities of all practitioners. In relation to the Improving Medicare Post-Acute Care Transformation (IMPACT) Act of 2014, the Centers for Medicare and Medicaid Services (CMS) is implementing new functional items and related outcome performance measures across postacute care (PAC) settings. Practitioners can demonstrate the role and value of occupational therapy services through their participation in data collection and the interpretation of the resulting performance measures. In this column, we review the objectives of the IMPACT Act, introduce the new self-care and mobility items and outcome performance measures being implemented in PAC settings, and describe ways to use these new data to advocate for occupational therapy. We also discuss American Occupational Therapy Association initiatives to provide materials and guidance for occupational therapy practitioners to contribute to PAC data collection. Copyright © 2018 by the American Occupational Therapy Association, Inc.

  4. SAGE 1 and SAM 2 measurements of 1 micron aerosol extinction in the free troposphere

    NASA Technical Reports Server (NTRS)

    Kent, G. S.; Farrukh, U. O.; Wang, P. H.; Deepak, A.

    1988-01-01

    The SAGE 1 and SAM 2 satellite sensors were designed to measure, with global coverage, the 1 micron extinction produced by the stratospheric aerosol. In the absence of high altitude cloud, similar measurements may be made for the free tropospheric aerosol. Median extinction values in the Northern Hemisphere, for altitudes between 5 and 10 km, are found to be one-half to one order of magnitude greater than values at corresponding latitudes in the Southern Hemisphere. In addition, a seasonal increase by a factor of 1.5 yields 2 is observed in both hemispheres in local spring and summer. Following major volcanic eruptions, a long-lived enhancement of the aerosol extinction is observed for altitudes above 5 km.

  5. Why social values cannot be changed for the sake of conservation.

    PubMed

    Manfredo, Michael J; Bruskotter, Jeremy T; Teel, Tara L; Fulton, David; Schwartz, Shalom H; Arlinghaus, Robert; Oishi, Shigehiro; Uskul, Ayse K; Redford, Kent; Kitayama, Shinobu; Sullivan, Leeann

    2017-08-01

    The hope for creating widespread change in social values has endured among conservation professionals since early calls by Aldo Leopold for a "land ethic." However, there has been little serious attention in conservation to the fields of investigation that address values, how they are formed, and how they change. We introduce a social-ecological systems conceptual approach in which values are seen not only as motivational goals people hold but also as ideas that are deeply embedded in society's material culture, collective behaviors, traditions, and institutions. Values define and bind groups, organizations, and societies; serve an adaptive role; and are typically stable across generations. When abrupt value changes occur, they are in response to substantial alterations in the social-ecological context. Such changes build on prior value structures and do not result in complete replacement. Given this understanding of values, we conclude that deliberate efforts to orchestrate value shifts for conservation are unlikely to be effective. Instead, there is an urgent need for research on values with a multilevel and dynamic view that can inform innovative conservation strategies for working within existing value structures. New directions facilitated by a systems approach will enhance understanding of the role values play in shaping conservation challenges and improve management of the human component of conservation. © 2016 The Authors. Conservation Biology published by Wiley Periodicals, Inc. on behalf of Society for Conservation Biology.

  6. Alternative method of quantum state tomography toward a typical target via a weak-value measurement

    NASA Astrophysics Data System (ADS)

    Chen, Xi; Dai, Hong-Yi; Yang, Le; Zhang, Ming

    2018-03-01

    There is usually a limitation of weak interaction on the application of weak-value measurement. This limitation dominates the performance of the quantum state tomography toward a typical target in the finite and high-dimensional complex-valued superposition of its basis states, especially when the compressive sensing technique is also employed. Here we propose an alternative method of quantum state tomography, presented as a general model, toward such typical target via weak-value measurement to overcome such limitation. In this model the pointer for the weak-value measurement is a qubit, and the target-pointer coupling interaction is no longer needed within the weak interaction limitation, meanwhile this interaction under the compressive sensing can be described with the Taylor series of the unitary evolution operator. The postselection state at the target is the equal superposition of all basis states, and the pointer readouts are gathered under multiple Pauli operator measurements. The reconstructed quantum state is generated from an optimization algorithm of total variation augmented Lagrangian alternating direction algorithm. Furthermore, we demonstrate an example of this general model for the quantum state tomography toward the planar laser-energy distribution and discuss the relations among some parameters at both our general model and the original first-order approximate model for this tomography.

  7. Can high seismic b-values be explained solely by poorly applied methodology?

    NASA Astrophysics Data System (ADS)

    Roberts, Nick; Bell, Andrew; Main, Ian

    2015-04-01

    The b-value of the Gutenberg-Richter distribution quantifies the relative proportion of large to small magnitude earthquakes in a catalogue, in turn related to the population of fault rupture areas and the average slip or stress drop. Accordingly the b-value is an important parameter to consider when evaluating seismic catalogues as it has the potential to provide insight into the temporal or spatial evolution of the system, such as fracture development or changes in the local stress regime. The b-value for tectonic seismicity is commonly found to be close to 1, whereas much higher b-values are frequently reported for volcanic and induced seismicity. Understanding these differences is important for understanding the processes controlling earthquake occurrence in different settings. However, it is possible that anomalously high b-values could arise from small sample sizes, under-estimated completeness magnitudes, or other poorly applied methodologies. Therefore, it is important to establish a rigorous workflow for analyzing these datasets. Here we examine the frequency-magnitude distributions of volcanic earthquake catalogues in order to determine the significance of apparently high b-values. We first derive a workflow for computing the completeness magnitude of a seismic catalogue, using synthetic catalogues of varying shape, size, and known b-value. We find the best approach involves a combination of three methods: 'Maximum Curvature', 'b-value stability', and the 'Goodness-of-Fit test'. To calculate a reliable b-value with an error ≤0.25, the maximum curvature method is preferred for a 'sharp-peaked' discrete distribution. For a catalogue with a broader peak the b-value stability method is the most reliable with the Goodness-of-Fit test being an acceptable backup if the b-value stability method fails. We apply this workflow to earthquake catalogues from El Hierro (2011-2013) and Mt Etna (1999-2013) volcanoes. In general, we find the b-value to be equal to or

  8. 18 CFR 801.11 - Public values.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Public values. 801.11... POLICIES § 801.11 Public values. (a) The basin has many points of archeological and historic interest, and... value of these areas cannot be measured simply in economic terms and will strive to preserve and promote...

  9. 18 CFR 801.11 - Public values.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... value of these areas cannot be measured simply in economic terms and will strive to preserve and promote... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Public values. 801.11... POLICIES § 801.11 Public values. (a) The basin has many points of archeological and historic interest, and...

  10. Using Value-Added Measures of Teacher Quality. Brief 9

    ERIC Educational Resources Information Center

    Hanushek, Eric A.; Rivkin, Steven G.

    2010-01-01

    Extensive education research on the contribution of teachers to student achievement produces two generally accepted results. First, teacher quality varies substantially as measured by the value added to student achievement or future academic attainment or earnings. Second, variables often used to determine entry into the profession and…

  11. Mapping from disease-specific measures to health-state utility values in individuals with migraine.

    PubMed

    Gillard, Patrick J; Devine, Beth; Varon, Sepideh F; Liu, Lei; Sullivan, Sean D

    2012-05-01

    The objective of this study was to develop empirical algorithms that estimate health-state utility values from disease-specific quality-of-life scores in individuals with migraine. Data from a cross-sectional, multicountry study were used. Individuals with episodic and chronic migraine were randomly assigned to training or validation samples. Spearman's correlation coefficients between paired EuroQol five-dimensional (EQ-5D) questionnaire utility values and both Headache Impact Test (HIT-6) scores and Migraine-Specific Quality-of-Life Questionnaire version 2.1 (MSQ) domain scores (role restrictive, role preventive, and emotional function) were examined. Regression models were constructed to estimate EQ-5D questionnaire utility values from the HIT-6 score or the MSQ domain scores. Preferred algorithms were confirmed in the validation samples. In episodic migraine, the preferred HIT-6 and MSQ algorithms explained 22% and 25% of the variance (R(2)) in the training samples, respectively, and had similar prediction errors (root mean square errors of 0.30). In chronic migraine, the preferred HIT-6 and MSQ algorithms explained 36% and 45% of the variance in the training samples, respectively, and had similar prediction errors (root mean square errors 0.31 and 0.29). In episodic and chronic migraine, no statistically significant differences were observed between the mean observed and the mean estimated EQ-5D questionnaire utility values for the preferred HIT-6 and MSQ algorithms in the validation samples. The relationship between the EQ-5D questionnaire and the HIT-6 or the MSQ is adequate to use regression equations to estimate EQ-5D questionnaire utility values. The preferred HIT-6 and MSQ algorithms will be useful in estimating health-state utilities in migraine trials in which no preference-based measure is present. Copyright © 2012 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  12. Behavioral Economic Measures of Alcohol Reward Value as Problem Severity Indicators in College Students

    PubMed Central

    Skidmore, Jessica R.; Murphy, James G.; Martens, Matthew P.

    2014-01-01

    The aims of the current study were to examine the associations among behavioral economic measures of alcohol value derived from three distinct measurement approaches, and to evaluate their respective relations with traditional indicators of alcohol problem severity in college drinkers. Five behavioral economic metrics were derived from hypothetical demand curves that quantify reward value by plotting consumption and expenditures as a function of price, another metric measured proportional behavioral allocation and enjoyment related to alcohol versus other activities, and a final metric measured relative discretionary expenditures on alcohol. The sample included 207 heavy drinking college students (53% female) who were recruited through an on-campus health center or university courses. Factor analysis revealed that the alcohol valuation construct comprises two factors: one factor that reflects participants’ levels of alcohol price sensitivity (demand persistence), and a second factor that reflects participants’ maximum consumption and monetary and behavioral allocation towards alcohol (amplitude of demand). The demand persistence and behavioral allocation metrics demonstrated the strongest and most consistent multivariate relations with alcohol-related problems, even when controlling for other well-established predictors. The results suggest that behavioral economic indices of reward value show meaningful relations with alcohol problem severity in young adults. Despite the presence of some gender differences, these measures appear to be useful problem indicators for men and women. PMID:24749779

  13. The iMTA Productivity Cost Questionnaire: A Standardized Instrument for Measuring and Valuing Health-Related Productivity Losses.

    PubMed

    Bouwmans, Clazien; Krol, Marieke; Severens, Hans; Koopmanschap, Marc; Brouwer, Werner; Hakkaart-van Roijen, Leona

    2015-09-01

    Productivity losses often contribute significantly to the total costs in economic evaluations adopting a societal perspective. Currently, no consensus exists on the measurement and valuation of productivity losses. We aimed to develop a standardized instrument for measuring and valuing productivity losses. A group of researchers with extensive experience in measuring and valuing productivity losses designed an instrument suitable for self-completion, building on preknowledge and evidence on validity. The instrument was designed to cover all domains of productivity losses, thus allowing quantification and valuation of all productivity losses. A feasibility study was performed to check the questionnaire's consistency and intelligibility. The iMTA Productivity Cost Questionnaire (iPCQ) includes three modules measuring productivity losses of paid work due to 1) absenteeism and 2) presenteeism and productivity losses related to 3) unpaid work. Questions for measuring absenteeism and presenteeism were derived from existing validated questionnaires. Because validated measures of losses of unpaid work are scarce, the questions of this module were newly developed. To enhance the instrument's feasibility, simple language was used. The feasibility study included 195 respondents (response rate 80%) older than 18 years. Seven percent (n = 13) identified problems while filling in the iPCQ, including problems with the questionnaire's instructions and routing (n = 6) and wording (n = 2). Five respondents experienced difficulties in estimating the time that would be needed for other people to make up for lost unpaid work. Most modules of the iPCQ are based on validated questions derived from previously available instruments. The instrument is understandable for most of the general public. Copyright © 2015 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  14. Carr-Purcell-Meiboom-Gill (CPMG) Imaging of Prostate Cancer: Quantitative T2 Values for Cancer Discrimination

    PubMed Central

    Roebuck, Joseph R.; Haker, Steven J.; Mitsouras, Dimitris; Rybicki, Frank J.; Tempany, Clare M.; Mulkern, Robert V.

    2009-01-01

    Quantitative, apparent T2 values of suspected prostate cancer and healthy peripheral zone tissue in men with prostate cancer were measured using a Carr-Purcell-Meiboom-Gill (CPMG) imaging sequence in order to assess the cancer discrimination potential of tissue T2 values. The CPMG imaging sequence was used to image the prostates of 18 men with biopsy proven prostate cancer. Whole gland coverage with nominal voxel volumes of 0.54 × 1.1 × 4 mm3 was obtained in 10.7 minutes, resulting in data sets suitable for generating high quality images with variable T2-weighting and for evaluating quantitative T2 values on a pixel-by-pixel basis. Region-of-interest analysis of suspected healthy peripheral zone tissue and suspected cancer, identified on the basis of both T1- and T2-weighted signal intensities and available histopathology reports, yielded significantly (p < 0.0001) longer apparent T2 values in suspected healthy tissue (193 ± 49 ms) vs. suspected cancer (100 ± 26 ms), suggesting potential utility of this method as a tissue specific discrimination index for prostate cancer. We conclude that CPMG imaging of the prostate can be performed in reasonable scan times and can provide advantages over T2-weighted fast spin echo imaging alone, including quantitative T2 values for cancer discrimination as well as proton density maps without the point spread function degradation associated with short effective echo time fast spin echo (FSE) sequences. PMID:18823731

  15. Measuring the ratio of CO2 efflux to O2 influx in tree stem respiration.

    PubMed

    Hilman, Boaz; Angert, Alon

    2016-11-01

    In recent studies, the ratio of tree stem CO 2 efflux to O 2 influx has been defined as the apparent respiratory quotient (ARQ). The metabolism of carbohydrates, the putative respiratory substrate in trees, is expected to yield an ARQ of 1.0. However, previous studies have reported ARQ values ranging between 0.23 and 0.90. These interesting results may indicate internal transport of respired CO 2 within stems; yet no simple field applicable methods for ARQ measurement have been available. Here, we report on the assembly of a closed circulating system called 'Hampadah', which uses CO 2 and O 2 analyzers to measure air samples from stem chambers. We tested the performance of the Hampadah with samples from 36 trees (Tetragastris panamensis (Engl.) Kuntze). Additionally, we showed the feasibility of measuring ARQ directly from stem chambers, using portable CO 2 and O 2 sensors, in both discrete and continuous modes of operation. The Hampadah measurement proved to be consistent with CO 2 gas standards (R 2 = 0.999) and with O 2 determined by O 2 /Ar measurements with a mass spectrometer (R 2 = 0.998). The Hampadah gave highly reproducible results for ARQ determination of field samples (±0.01 for duplicates). The portable sensors measurement showed good correlation with the Hampadah in measuring CO 2 , O 2 and ARQ (n = 5, R 2 = 0.97, 0.98 and 0.91, respectively). We have demonstrated here that the Hampadah and the sensors' methods enable accurate ARQ measurements for both laboratory and field research. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  16. Property Values as a Measure of Neighborhoods: An Application of Hedonic Price Theory.

    PubMed

    Leonard, Tammy; Powell-Wiley, Tiffany M; Ayers, Colby; Murdoch, James C; Yin, Wenyuan; Pruitt, Sandi L

    2016-07-01

    Researchers measuring relationships between neighborhoods and health have begun using property appraisal data as a source of information about neighborhoods. Economists have developed a rich tool kit to understand how neighborhood characteristics are quantified in appraisal values. This tool kit principally relies on hedonic (implicit) price models and has much to offer regarding the interpretation and operationalization of property appraisal data-derived neighborhood measures, which goes beyond the use of appraisal data as a measure of neighborhood socioeconomic status. We develop a theoretically informed hedonic-based neighborhood measure using residuals of a hedonic price regression applied to appraisal data in a single metropolitan area. We describe its characteristics, reliability in different types of neighborhoods, and correlation with other neighborhood measures (i.e., raw neighborhood appraisal values, census block group poverty, and observed property characteristics). We examine the association between all neighborhood measures and body mass index. The hedonic-based neighborhood measure was correlated in the expected direction with block group poverty rate and observed property characteristics. The neighborhood measure and average raw neighborhood appraisal value, but not census block group poverty, were associated with individual body mass index. We draw theoretically consistent methodology from the economics literature on hedonic price models to demonstrate how to leverage the implicit valuation of neighborhoods contained in publicly available appraisal data. Consistent measurement and application of the hedonic-based neighborhood measures in epidemiology will improve understanding of the relationships between neighborhoods and health. Researchers should proceed with a careful use of appraisal values utilizing theoretically informed methods such as this one.

  17. Looking Good or Being Good? The Role of Social Desirability Tendencies in Student Perceptions of Institutional Mission and Values

    ERIC Educational Resources Information Center

    Ferrari, Joseph R.; Bristow, Maya; Cowman, Shaun E.

    2005-01-01

    Two samples of college students (Sample 1, n = 106 Sample 2, n = 107) completed self-report measures that assessed their perceptions of their university's mission and values along with their tendency to seek social approval. With Sample 1, global social desirability was not predictive of any student perceptions related to institutional mission and…

  18. ARFI quantitative elastography of the submandibular glands. Normal measurements and the diagnosis value of the method in radiation submaxillitis.

    PubMed

    Badea, Alexandru Florin; Tamas Szora, Attila; Ciuleanu, Elisabeta; Chioreanu, Ioana; Băciuţ, Grigore; Lupşor Platon, Monica; Badea, Radu

    2013-09-01

    Evaluation of Acoustic Radiation Force Impulse Imaging (ARFI) elastography performance in predicting the elasticity of the submandibular glands in normal situations and after radiation therapy. A number of 54 normal submandibular glands from 27 voluntary subjects and 33 pathological submandibular glands (radiation submaxillities) from 18 patients who had undergone radiation therapy for various cervical and facial oncological conditions were included in study. All the patients had undergone a B mode ultrasonography (Tissue Harmonic Imaging, 8-14 MHz) while the submandibular volume was determined and subsequently an ARFI examination while the shear wave velocity (SWV) was measured (in the central, peripheral and subcapsular areas, with the results expressed in m/s). In the volunteers' group the mean value of the SWV of the left submandibular gland was 1.68 ± 0.46 m/s, determined in the centre of the gland, 1.88 ± 0.4 m/s in the periphery (corresponding to the subcapsular parenchyma) and the SWV of the right submandibular gland was 1.74 ± 0.35 m/s (centrally) and 1.84 ± 0.43 m/s in the periphery. The mean value of all measurements was 1.82 ± 0.41 m/s. The mean volume of the glands was 7.97 ± 2.63 cm3. In the group of patients who had underwent radiation therapy (at least 35Gy), the mean value of the SWV was 2.24 ± 0.49 m/s centrally and 2.1 ± 0.58 m/s in the periphery on the left and 1.99 ± 0.5 m/s centrally and 2.21 ± 0.52 m/s in the periphery on the right. The mean value of all the measurements was 2.13 ± 0.52 m/s and the mean volume of the gland was 5.95 ± 4.16 cm3. Elastography using ARFI technique is a valid examination in the evaluation of the normal and pathological submandibular gland stiffness. The values of the shear wave velocities that correspond to a normal stiffness, determined through the ARFI technique, are similar in the two glands. After cervical and facial radiation therapy the values of the SWV are increased, indicating a change in the

  19. Measuring Value-at-Risk and Expected Shortfall of crude oil portfolio using extreme value theory and vine copula

    NASA Astrophysics Data System (ADS)

    Yu, Wenhua; Yang, Kun; Wei, Yu; Lei, Likun

    2018-01-01

    Volatilities of crude oil price have important impacts on the steady and sustainable development of world real economy. Thus it is of great academic and practical significance to model and measure the volatility and risk of crude oil markets accurately. This paper aims to measure the Value-at-Risk (VaR) and Expected Shortfall (ES) of a portfolio consists of four crude oil assets by using GARCH-type models, extreme value theory (EVT) and vine copulas. The backtesting results show that the combination of GARCH-type-EVT models and vine copula methods can produce accurate risk measures of the oil portfolio. Mixed R-vine copula is more flexible and superior to other vine copulas. Different GARCH-type models, which can depict the long-memory and/or leverage effect of oil price volatilities, however offer similar marginal distributions of the oil returns.

  20. Estimating Values of H2O-ACTIVITIES in the Mantle Using Amphibole Equilibria

    NASA Astrophysics Data System (ADS)

    Lamb, W. M.; Hunt, L. E.

    2017-12-01

    Determining values of H2O activity (aH2O) for mantle rocks will yield a better understanding of those mantle processes that are controlled, in part, by the availability of H2O (e.g., melting and deformation). The H contents of the upper mantle can be estimated from amount of H contained in nominally anhydrous minerals (NAMs). However, for many common NAMs, the relation between aH2O and H content is not well known, and certain NAMs may be prone to retrograde H loss. The activities of H2O and other fluids species (e.g., CO2) may be estimated using mineral equilibria. Equilibria involving amphibole can, for example, be used to estimate values of aH2O and hydrogen fugacity (ƒH2). Spinel equilibria can be applied to estimate values of oxygen fugacity (ƒO2) that, when combined with ƒH2, will provide a second estimate of aH2O. We have characterized mineral chemistries in 11 amphibole-bearing peridotite xenoliths from the southwestern U.S.A. The compositions of co-existing pyroxenes ± garnet yield P-T conditions of ≈ 1.1 GPa, and 880 to 980˚C, and application of dehydration equilibria yields values of aH2O ranging from 0.04 to 0.19. The compositions of coexisting spinel + olivine + opx yield DlogƒO2(FMQ) of -0.2 to +0.9. Values of ƒH2, estimated using amphibole dehydrogenation equilibria (6 to 91 bars) were combined with values of ƒO2 to estimate aH2O in nine samples (≈ 0.02 to 0.12). The difference between these two values of aH2O, estimated using dehydration equilibria versus ƒH2 + ƒO2, is generally < 0.1, suggesting that the amphiboles experienced little or no retrograde H-loss. All samples equilibrated at low values of aH2O, and these values may be used to predict NAM H-contents. For example, according to Gaetani et al. (2014, Cont. Min. Pet., p. 965), the concentration of H in olivine is a function of P, T, the fugacities of H2O and O2, and olivine composition. Their relation yields relatively low predicted H-contents of 10 to 28 wt. ppm for olivine in

  1. Mathematical values in the processing of Chinese numeral classifiers and measure words.

    PubMed

    Her, One-Soon; Chen, Ying-Chun; Yen, Nai-Shing

    2017-01-01

    A numeral classifier is required between a numeral and a noun in Chinese, which comes in two varieties, sortal classifer (C) and measural classifier (M), also known as 'classifier' and 'measure word', respectively. Cs categorize objects based on semantic attributes and Cs and Ms both denote quantity in terms of mathematical values. The aim of this study was to conduct a psycholinguistic experiment to examine whether participants process C/Ms based on their mathematical values with a semantic distance comparison task, where participants judged which of the two C/M phrases was semantically closer to the target C/M. Results showed that participants performed more accurately and faster for C/Ms with fixed values than the ones with variable values. These results demonstrated that mathematical values do play an important role in the processing of C/Ms. This study may thus shed light on the influence of the linguistic system of C/Ms on magnitude cognition.

  2. Biases in Multicenter Longitudinal PET Standardized Uptake Value Measurements1

    PubMed Central

    Doot, Robert K; Pierce, Larry A; Byrd, Darrin; Elston, Brian; Allberg, Keith C; Kinahan, Paul E

    2014-01-01

    This study investigates measurement biases in longitudinal positron-emission tomography/computed tomography (PET/CT) studies that are due to instrumentation variability including human error. Improved estimation of variability between patient scans is of particular importance for assessing response to therapy and multicenter trials. We used National Institute of Standards and Technology-traceable calibration methodology for solid germanium-68/gallium-68 (68Ge/68Ga) sources used as surrogates for fluorine-18 (18F) in radionuclide activity calibrators. One cross-calibration kit was constructed for both dose calibrators and PET scanners using the same 9-month half-life batch of 68Ge/68Ga in epoxy. Repeat measurements occurred in a local network of PET imaging sites to assess standardized uptake value (SUV) errors over time for six dose calibrators from two major manufacturers and for six PET/CT scanners from three major manufacturers. Bias in activity measures by dose calibrators ranged from -50% to 9% and was relatively stable over time except at one site that modified settings between measurements. Bias in activity concentration measures by PET scanners ranged from -27% to 13% with a median of 174 days between the six repeat scans (range, 29 to 226 days). Corresponding errors in SUV measurements ranged from -20% to 47%. SUV biases were not stable over time with longitudinal differences for individual scanners ranging from -11% to 59%. Bias in SUV measurements varied over time and between scanner sites. These results suggest that attention should be paid to PET scanner calibration for longitudinal studies and use of dose calibrator and scanner cross-calibration kits could be helpful for quality assurance and control. PMID:24772207

  3. Life values and self-regulation behaviours among adults with type 2 diabetes.

    PubMed

    Oftedal, Bjørg; Karlsen, Bjørg; Bru, Edvin

    2010-09-01

    The aim of this study was to identify life values in adults with type 2 diabetes and to describe their experiences of how these values may influence self-regulation behaviours. Daily self-regulation behaviours have been described as challenging, because the individuals try to find a balance between them and life values. However, little is known about how life values may influence the motivation for necessary self-regulation behaviours. A descriptive/explorative qualitative design that included focus groups was used to collect data. The sample consisted of 19 adults with type 2 diabetes. Data were analysed using qualitative content analysis. The findings revealed six themes: maintaining health and longevity, a feeling of bodily well-being, preserving a positive body image, self-determination, maintaining the ability to work and belonging. The results reflect the fact that many life values have a major influence on self-regulation behaviours. The findings indicate that several of the life values can conflict with self-regulation behaviours, which in turn may influence the motivation for self-regulation of type 2 diabetes. Some of these values could be considered to be related to self-worth, which is regarded as an important motivational component for engaging in a task. Moreover, this study highlights the fact that goals related to self-regulation behaviours were formulated in more general than in specific terms. This study may help health professionals to understand how adults' life values influence their motivation for adequate self-regulation. The findings indicate that the existing support structures should make an effort to learn about people's life values and take them into account when giving advice about self-regulation behaviours. Moreover, people with type 2 diabetes should be supported by health professionals to set more specific self-regulation goals that are consistent with their life values. © 2010 Blackwell Publishing Ltd.

  4. Weak values and weak coupling maximizing the output of weak measurements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Di Lorenzo, Antonio, E-mail: dilorenzo.antonio@gmail.com

    2014-06-15

    In a weak measurement, the average output 〈o〉 of a probe that measures an observable A{sup -hat} of a quantum system undergoing both a preparation in a state ρ{sub i} and a postselection in a state E{sub f} is, to a good approximation, a function of the weak value A{sub w}=Tr[E{sub f}A{sup -hat} ρ{sub i}]/Tr[E{sub f}ρ{sub i}], a complex number. For a fixed coupling λ, when the overlap Tr[E{sub f}ρ{sub i}] is very small, A{sub w} diverges, but 〈o〉 stays finite, often tending to zero for symmetry reasons. This paper answers the questions: what is the weak value that maximizesmore » the output for a fixed coupling? What is the coupling that maximizes the output for a fixed weak value? We derive equations for the optimal values of A{sub w} and λ, and provide the solutions. The results are independent of the dimensionality of the system, and they apply to a probe having a Hilbert space of arbitrary dimension. Using the Schrödinger–Robertson uncertainty relation, we demonstrate that, in an important case, the amplification 〈o〉 cannot exceed the initial uncertainty σ{sub o} in the observable o{sup -hat}, we provide an upper limit for the more general case, and a strategy to obtain 〈o〉≫σ{sub o}. - Highlights: •We have provided a general framework to find the extremal values of a weak measurement. •We have derived the location of the extremal values in terms of preparation and postselection. •We have devised a maximization strategy going beyond the limit of the Schrödinger–Robertson relation.« less

  5. Cultural values and happiness: an East-West dialogue.

    PubMed

    Luo, L; Gilmour, R; Kao, S F

    2001-08-01

    Happiness as a state of mind may be universal, but its meaning is complex and ambiguous. The authors directly examined the relationships between cultural values and experiences of happiness in 2 samples, by using a measurement of values derived from Chinese culture and a measurement of subjective well-being balanced for sources of happiness salient in both the East and the West. The participants were university students-439 from an Eastern culture (Taiwan) and 344 from a Western culture (the United Kingdom). Although general patterns were similar in the 2 samples, the relationships between values and happiness were stronger in the Taiwanese sample than in the British sample. The values social integration and human-heartedness had culture-dependent effects on happiness, whereas the value Confucian work dynamism had a culture-general effect on happiness.

  6. Congruence and functions of personal and cultural values: do my values reflect my culture's values?

    PubMed

    Fischer, Ronald

    2006-11-01

    Two studies are described examining the correlation between self- and culture-referenced values at a culture level (Study 1) and correlation between self- and culture-referenced values and self-reported behavior at an individual level (Study 2). It is found that values related to individual-group relationships (embeddedness) and expression and experience of affective feelings and emotions (affective autonomy) are significantly correlated at a culture level. In Study 2, culture-referenced values are shown to correlate with behaviors attached to social norms, whereas self-rated values are found to correlate with behaviors that are not norm-governed. Implications for measurement of cultural values and cultural and cross-cultural research designs are discussed.

  7. Value of digit ratio 2D:4D, a biomarker of prenatal hormone exposure, is stable across the menstrual cycle.

    PubMed

    Klimek, Magdalena; Marcinkowska, Urszula M; Jasienska, Grazyna

    2017-07-01

    Digit ratio (2D:4D) is used as a marker of prenatal hormone exposure and, consequently, as a predictor of many characteristics throughout a woman's lifespan. A previous study has suggested that values of 2D:4D vary across menstrual cycles and further questioned the reliability of a single measurement of 2D:4D among cycling women, while another study failed to confirm these results. However, these studies estimated the timing of cycle phases based on a date of menstruation reported by participants and also had small sample sizes. For our study, we evaluated potential changes in 2D:4D values across a menstrual cycle in a group of women among whom the phases of the menstrual cycle were determined by hormonal (luteinizing hormone based) ovulation tests. We studied 32 naturally cycling women aged 22-37 from rural Poland. Lengths of second and fourth digits were measured based on scans of both hands taken three times (i.e. in the follicular phase, peri-ovulatory phase and luteal phase of the cycle) for each participant. No differences in 2D:4D value across the menstrual cycle were detected either when right-hand, left-hand, and mean 2D:4D for both hands were analysed, nor when difference in the 2D:4D value between hands (D left-right ) was evaluated. We documented that 2D:4D is independent of the phase of the menstrual cycle and these findings suggest that among naturally cycling women, a value of 2D:4D can be reliably obtained from measurements taken during any day of the menstrual cycle. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. The Math-Biology Values Instrument: Development of a Tool to Measure Life Science Majors' Task Values of Using Math in the Context of Biology.

    PubMed

    Andrews, Sarah E; Runyon, Christopher; Aikens, Melissa L

    2017-01-01

    In response to calls to improve the quantitative training of undergraduate biology students, there have been increased efforts to better integrate math into biology curricula. One challenge of such efforts is negative student attitudes toward math, which are thought to be particularly prevalent among biology students. According to theory, students' personal values toward using math in a biological context will influence their achievement and behavioral outcomes, but a validated instrument is needed to determine this empirically. We developed the Math-Biology Values Instrument (MBVI), an 11-item college-level self--report instrument grounded in expectancy-value theory, to measure life science students' interest in using math to understand biology, the perceived usefulness of math to their life science career, and the cost of using math in biology courses. We used a process that integrates multiple forms of validity evidence to show that scores from the MBVI can be used as a valid measure of a student's value of math in the context of biology. The MBVI can be used by instructors and researchers to help identify instructional strategies that influence math-biology values and understand how math-biology values are related to students' achievement and decisions to pursue more advanced quantitative-based courses. © 2017 S. E. Andrews et al. CBE—Life Sciences Education © 2017 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  9. First Measurements of Time-Dependent Nucleation as a Function of Composition in Na2O.2CaO.3SiO2 Glasses

    NASA Technical Reports Server (NTRS)

    Kelton, K. F.; Narayan, K. Lakshmi

    1996-01-01

    The first measurements in any system of the composition dependence of the time-dependent nucleation rate are presented Nucleation rates of the stoichiometric crystalline phase, Na2O.2CaO.3SiO2, from quenched glasses made with different SiO2 concentrations were determined as a function of temperature and glass composition. A strong compositional dependence of the nucleation rates and a weak dependence for the induction times are observed. Using measured values of the liquidus temperatures and growth velocities as a function of glass composition, these data are shown to be consistent with predictions from the classical theory of nucleation, assuming a composition-dependent interfacial energy.

  10. Measuring striving for understanding and learning value of geometry: a validity study

    NASA Astrophysics Data System (ADS)

    Ubuz, Behiye; Aydınyer, Yurdagül

    2017-11-01

    The current study aimed to construct a questionnaire that measures students' personality traits related to striving for understanding and learning value of geometry and then examine its psychometric properties. Through the use of multiple methods on two independent samples of 402 and 521 middle school students, two studies were performed to address this issue to provide support for its validity. In Study 1, exploratory factor analysis indicated the two-factor model. In Study 2, confirmatory factor analysis indicated the better fit of two-factor model compared to one or three-factor model. Convergent and discriminant validity evidence provided insight into the distinctiveness of the two factors. Subgroup validity evidence revealed gender differences for striving for understanding geometry trait favouring girls and grade level differences for learning value of geometry trait favouring the sixth- and seventh-grade students. Predictive validity evidence demonstrated that the striving for understanding geometry trait but not learning value of geometry trait was significantly correlated with prior mathematics achievement. In both studies, each factor and the entire questionnaire showed satisfactory reliability. In conclusion, the questionnaire was psychometrically sound.

  11. Measuring the value of endoscopic retrograde cholangiopancreatography activity: an opportunity to stratify endoscopists on the basis of their value.

    PubMed

    Parihar, Vikrant; Moran, Carthage; Maheshwari, Pardeep; Cheriyan, Danny; O'Toole, Aoibhlinn; Murray, Frank; Patchett, Stephen E; Harewood, Gavin C

    2018-07-01

    As finite healthcare resources come under pressure, the value of physician activity is assuming increasing importance. The value in healthcare can be defined as patient health outcomes achieved per monetary unit spent. Even though some attempts have been made to quantify the value of clinician activity, there is little in the medical literature describing the importance of endoscopists' activity. This study aimed to characterize the value of endoscopic retrograde cholangiopancreatography (ERCP) performance of five gastroenterologists. We carried out a retrospective-prospective cohort study using the databases of patients undergoing ERCP between September 2014 and March 2017. We collected data from 1070 patients who underwent ERCP comparing value among the ERCPists at index ERCP. Procedure value was calculated using the formula Q/(T/C), where Q is the quality of procedure, T is the duration of procedure and C is the adjusted for complexity level. Quality and complexity were derived on a 1-4 Likert scale on the basis of American Society for Gastrointestinal Endoscopy criteria; time was recorded (in min) from intubation to extubation. Endoscopist time calculated from procedure time was considered a surrogate marker of cost as individual components of procedure cost were not itemized. In total, 590 procedures were analysed: 465 retrospectively over 24 months and 125 prospectively over 6 months. There was a 32% variation in the value of endoscopist activity in a more substantial retrospective cohort, with an even more considerable 73% variation in a smaller prospective arm. In an analysis of greater than 1000 ERCPs by a small cohort of experienced ERCPists, there was a wide variation in the value of endoscopist activity. Although the precision of estimating procedural costs needs further refinement, these findings show the ability to stratify ERCPists on the basis of the value their activity. As healthcare costs are scrutinized more closely, such value measurements are

  12. Development and Preliminary Validation of a New Measure of Values in Scientific Work.

    PubMed

    English, Tammy; Antes, Alison L; Baldwin, Kari A; DuBois, James M

    2018-04-01

    In this paper we describe the development and initial psychometric evaluation of a new measure, the values in scientific work (VSW). This scale assesses the level of importance that investigators attach to different VSW. It taps a broad range of intrinsic, extrinsic, and social values that motivate the work of scientists, including values specific to scientific work (e.g., truth and integrity) and more classic work values (e.g., security and prestige) in the context of science. Notably, the values represented in this scale are relevant to scientists regardless of their career stage and research focus. We administered the VSW and a measure of global values to 203 NIH-funded investigators. Exploratory factor analyses suggest the delineation of eight VSW, including autonomy, research ethics, social impact, income, collaboration, innovation and growth, conserving relationships, and job security. These VSW showed predictable and distinct associations with global values. Implications of these findings for work on research integrity and scientific misconduct are discussed.

  13. Using Publicly Available Data to Construct a Transparent Measure of Health Care Value: A Method and Initial Results.

    PubMed

    Weeks, William B; Kotzbauer, Gregory R; Weinstein, James N

    2016-06-01

    hospitals, but were no more likely to be accredited by the Joint Commission or to have a residency program accredited by the American Council of Graduate Medical Education. While future efforts to compose value measures will certainly be modified and expanded to examine other reasons for admission, the construct that we present could allow patients to transparently compare procedure- and hospital-specific quality, spending, and value and empower them to decide where to obtain care. © 2016 Milbank Memorial Fund.

  14. Measuring and Communicating the Value Created by an Organization

    ERIC Educational Resources Information Center

    Sherman, W. Richard

    2010-01-01

    This paper offers a different perspective in measuring the value created by an organization. It does so in the context of an undergraduate course in managerial accounting. In order to break down the functional silo approach to problem solving that has become the model of traditional business education, applications of shadow accounting, the…

  15. Evaluating Frameworks That Provide Value Measures for Health Care Interventions.

    PubMed

    Mandelblatt, Jeanne S; Ramsey, Scott D; Lieu, Tracy A; Phelps, Charles E

    2017-02-01

    The recent acceleration of scientific discovery has led to greater choices in health care. New technologies, diagnostic tests, and pharmaceuticals have widely varying impact on patients and populations in terms of benefits, toxicities, and costs, stimulating a resurgence of interest in the creation of frameworks intended to measure value in health. Many of these are offered by providers and/or advocacy organizations with expertise and interest in specific diseases (e.g., cancer and heart disease). To help assess the utility of and the potential biases embedded in these frameworks, we created an evaluation taxonomy with seven basic components: 1) define the purpose; 2) detail the conceptual approach, including perspectives, methods for obtaining preferences of decision makers (e.g., patients), and ability to incorporate multiple dimensions of value; 3) discuss inclusions and exclusions of elements included in the framework, and whether the framework assumes clinical intervention or offers alternatives such as palliative care or watchful waiting; 4) evaluate data sources and their scientific validity; 5) assess the intervention's effect on total costs of treating a defined population; 6) analyze how uncertainty is incorporated; and 7) illuminate possible conflicts of interest among those creating the framework. We apply the taxonomy to four representative value frameworks recently published by professional organizations focused on treatment of cancer and heart disease and on vaccine use. We conclude that each of these efforts has strengths and weaknesses when evaluated using our taxonomy, and suggest pathways to enhance the utility of value-assessing frameworks for policy and clinical decision making. Copyright © 2017 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  16. Adaptive Measurement of Well-Being: Maximizing Efficiency and Optimizing User Experience during Individual Assessment

    PubMed Central

    Kraatz, Miriam; Coberley, Carter R.; Pope, James E.

    2016-01-01

    Abstract Well-being is linked to important societal factors such as health care costs and productivity and has experienced a surge in development activity of both theories and measurement. This study builds on validation of the Well-Being 5 survey and for the first time applies Item Response Theory, a modern and flexible measurement paradigm, to form the basis of adaptive population well-being measurement. Adaptive testing allows survey questions to be administered selectively, thereby reducing the number of questions required of the participant. After the graded response model was fit to a sample of size N = 12,035, theta scores were estimated based on both the full-item bank and a simulation of Computerized Adaptive Testing (CAT). Comparisons of these 2 sets of score estimates with each other and of their correlations with external outcomes of job performance, absenteeism, and hospital admissions demonstrate that the CAT well-being scores maintain accuracy and validity. The simulation indicates that the average survey taker can expect a reduction in number of items administered during the CAT process of almost 50%. An increase in efficiency of this extent is of considerable value because of the time savings during the administration of the survey and the potential improvement of user experience, which in turn can help secure the success of a total population-based well-being improvement program. (Population Health Management 2016;19:284–290) PMID:26674396

  17. Equating Semi-Continuous (SC) PM2.5 Mass Monitor Measurement Values with Federal Reference Method (FRM) PM2.5 Monitor Measurement Values

    EPA Science Inventory

    The effects of fine particulate matter (PM2.5) on human health are well documented (Pope et al., 2002). In order to spatially and temporally assess the impact of PM2.5 on the U.S. population, the U.S. Environmental Protection Agency (U.S. EPA) operates a ne...

  18. Accounting for one-channel depletion improves missing value imputation in 2-dye microarray data.

    PubMed

    Ritz, Cecilia; Edén, Patrik

    2008-01-19

    For 2-dye microarray platforms, some missing values may arise from an un-measurably low RNA expression in one channel only. Information of such "one-channel depletion" is so far not included in algorithms for imputation of missing values. Calculating the mean deviation between imputed values and duplicate controls in five datasets, we show that KNN-based imputation gives a systematic bias of the imputed expression values of one-channel depleted spots. Evaluating the correction of this bias by cross-validation showed that the mean square deviation between imputed values and duplicates were reduced up to 51%, depending on dataset. By including more information in the imputation step, we more accurately estimate missing expression values.

  19. Influence of extraction solvent on antioxidant capacity value of oleaster measured by ORAC method.

    PubMed

    Yalcin, Gorkem; Sogut, Ozlem

    2014-01-01

    Oxygen radical absorbance capacity (ORAC) is a widely used hydrogen atom transfer-based method which measures the antioxidant capacity of natural products. ORAC values of oleaster (Elaeagnus angustifolia L.), which was extracted with ethanol/acetone (7:3, v/v), ethanol/water (1:1, v/v) and methanol/water (1:1, v/v) in order to evaluate the effects of solvent type on antioxidant capacity, were examined. In general, results revealed that ethanol/water extracts exhibited better antioxidant capacity values. Furthermore, results obtained by using ORAC-eosin y (ORAC-EY), one of the widely used derivative of fluorescein (FL), as a fluorescent probe were compared with those obtained by using ORAC-FL. According to the results, ORAC-EY values were found to be compatible with ORAC-FL values.

  20. A National Trial on Differences in Cerebral Perfusion Pressure Values by Measurement Location.

    PubMed

    McNett, Molly M; Bader, Mary Kay; Livesay, Sarah; Yeager, Susan; Moran, Cristina; Barnes, Arianna; Harrison, Kimberly R; Olson, DaiWai M

    2018-04-01

    Cerebral perfusion pressure (CPP) is a key parameter in management of brain injury with suspected impaired cerebral autoregulation. CPP is calculated by subtracting intracranial pressure (ICP) from mean arterial pressure (MAP). Despite consensus on importance of CPP monitoring, substantial variations exist on anatomical reference points used to measure arterial MAP when calculating CPP. This study aimed to identify differences in CPP values based on measurement location when using phlebostatic axis (PA) or tragus (Tg) as anatomical reference points. The secondary study aim was to determine impact of differences on patient outcomes at discharge. This was a prospective, repeated measures, multi-site national trial. Adult ICU patients with neurological injury necessitating ICP and CPP monitoring were consecutively enrolled from seven sites. Daily MAP/ICP/CPP values were gathered with the arterial transducer at the PA, followed by the Tg as anatomical reference points. A total of 136 subjects were enrolled, resulting in 324 paired observations. There were significant differences for CPP when comparing values obtained at PA and Tg reference points (p < 0.000). Differences remained significant in repeated measures model when controlling for clinical factors (mean CPP-PA = 80.77, mean CPP-Tg = 70.61, p < 0.000). When categorizing CPP as binary endpoint, 18.8% of values were identified as adequate with PA values, yet inadequate with CPP values measured at the Tg. Findings identify numerical differences for CPP based on anatomical reference location and highlight importance of a standard reference point for both clinical practice and future trials to limit practice variations and heterogeneity of findings.

  1. Start a New Fire: Measuring the Value of Academic Libraries in Undergraduate Learning

    ERIC Educational Resources Information Center

    Menchaca, Frank

    2014-01-01

    In the last two decades, fundamental changes in information distribution, in the general economy, and in the behaviors of faculty, students, and library staff have problematized the question of an academic library's value and how it can be measured. This article reviews those changes and, drawing on research linked to the Collegiate Learning…

  2. The Value of Body Weight Measurement to Assess Dehydration in Children

    PubMed Central

    Pruvost, Isabelle; Dubos, François; Chazard, Emmanuel; Hue, Valérie; Duhamel, Alain; Martinot, Alain

    2013-01-01

    Dehydration secondary to gastroenteritis is one of the most common reasons for office visits and hospital admissions. The indicator most commonly used to estimate dehydration status is acute weight loss. Post-illness weight gain is considered as the gold-standard to determine the true level of dehydration and is widely used to estimate weight loss in research. To determine the value of post-illness weight gain as a gold standard for acute dehydration, we conducted a prospective cohort study in which 293 children, aged 1 month to 2 years, with acute diarrhea were followed for 7 days during a 3-year period. The main outcome measures were an accurate pre-illness weight (if available within 8 days before the diarrhea), post-illness weight, and theoretical weight (predicted from the child’s individual growth chart). Post-illness weight was measured for 231 (79%) and both theoretical and post-illness weights were obtained for 111 (39%). Only 62 (21%) had an accurate pre-illness weight. The correlation between post-illness and theoretical weight was excellent (0.978), but bootstrapped linear regression analysis showed that post-illness weight underestimated theoretical weight by 0.48 kg (95% CI: 0.06–0.79, p<0.02). The mean difference in the fluid deficit calculated was 4.0% of body weight (95% CI: 3.2–4.7, p<0.0001). Theoretical weight overestimated accurate pre-illness weight by 0.21 kg (95% CI: 0.08–0.34, p = 0.002). Post-illness weight underestimated pre-illness weight by 0.19 kg (95% CI: 0.03–0.36, p = 0.02). The prevalence of 5% dehydration according to post-illness weight (21%) was significantly lower than the prevalence estimated by either theoretical weight (60%) or clinical assessment (66%, p<0.0001).These data suggest that post-illness weight is of little value as a gold standard to determine the true level of dehydration. The performance of dehydration signs or scales determined by using post-illness weight as a gold standard has to be

  3. A scheme of quantum state discrimination over specified states via weak-value measurement

    NASA Astrophysics Data System (ADS)

    Chen, Xi; Dai, Hong-Yi; Liu, Bo-Yang; Zhang, Ming

    2018-04-01

    The commonly adopted projective measurements are invalid in the specified task of quantum state discrimination when the discriminated states are superposition of planar-position basis states whose complex-number probability amplitudes have the same magnitude but different phases. Therefore we propose a corresponding scheme via weak-value measurement and examine the feasibility of this scheme. Furthermore, the role of the weak-value measurement in quantum state discrimination is analyzed and compared with one in quantum state tomography in this Letter.

  4. Reference Values for Body Composition and Anthropometric Measurements in Athletes

    PubMed Central

    Santos, Diana A.; Dawson, John A.; Matias, Catarina N.; Rocha, Paulo M.; Minderico, Cláudia S.; Allison, David B.; Sardinha, Luís B.; Silva, Analiza M.

    2014-01-01

    Background Despite the importance of body composition in athletes, reference sex- and sport-specific body composition data are lacking. We aim to develop reference values for body composition and anthropometric measurements in athletes. Methods Body weight and height were measured in 898 athletes (264 female, 634 male), anthropometric variables were assessed in 798 athletes (240 female and 558 male), and in 481 athletes (142 female and 339 male) with dual-energy X-ray absorptiometry (DXA). A total of 21 different sports were represented. Reference percentiles (5th, 25th, 50th, 75th, and 95th) were calculated for each measured value, stratified by sex and sport. Because sample sizes within a sport were often very low for some outcomes, the percentiles were estimated using a parametric, empirical Bayesian framework that allowed sharing information across sports. Results We derived sex- and sport-specific reference percentiles for the following DXA outcomes: total (whole body scan) and regional (subtotal, trunk, and appendicular) bone mineral content, bone mineral density, absolute and percentage fat mass, fat-free mass, and lean soft tissue. Additionally, we derived reference percentiles for height-normalized indexes by dividing fat mass, fat-free mass, and appendicular lean soft tissue by height squared. We also derived sex- and sport-specific reference percentiles for the following anthropometry outcomes: weight, height, body mass index, sum of skinfold thicknesses (7 skinfolds, appendicular skinfolds, trunk skinfolds, arm skinfolds, and leg skinfolds), circumferences (hip, arm, midthigh, calf, and abdominal circumferences), and muscle circumferences (arm, thigh, and calf muscle circumferences). Conclusions These reference percentiles will be a helpful tool for sports professionals, in both clinical and field settings, for body composition assessment in athletes. PMID:24830292

  5. Measuring value for low-acuity care across settings.

    PubMed

    Morgan, Sofie Rahman; Smith, Meaghan A; Pitts, Stephen R; Shesser, Robert; Uscher-Pines, Lori; Ward, Michael J; Pines, Jesse M

    2012-09-01

    Increasing healthcare costs have created an emphasis on improving value, defined as how invested time, money, and resources improve health. The role of emergency departments (EDs) within value-driven health systems is still undetermined. Often questioned is the value of an ED visit for conditions that could be reasonably treated elsewhere such as office-based, urgent, and retail clinics. This paper presents a conceptual approach to assess the value of these low-acuity visits. It adapts an existing analytic model to highlight specific factors that impact key stakeholders' (patients, insurers, and society) assessments of the value of ED-based care compared with care in alternative settings. These factors are presented in 3 equations, 1 for each stakeholder, emphasizing how tangible and intangible benefits of care weigh against direct and indirect costs and how each perspective influences value. Aligning value among groups could allow stakeholders to influence each other and could guide rational change in the delivery of acute medical care for low-acuity conditions.

  6. Workshop: Using Contingent Valuation to Measure Non-Market Values (1994)

    EPA Pesticide Factsheets

    Workshop co-hosted by USEPA and Dept of Energy on using contingent valuation to measure non-market values for improvement in health and the environment. Includes transcripts of presentations and discussion by attendees, later published as a book.

  7. Quantitative evaluation of hyaline articular cartilage T2 maps of knee and determine the relationship of cartilage T2 values with age, gender, articular changes.

    PubMed

    Cağlar, E; Şahin, G; Oğur, T; Aktaş, E

    2014-11-01

    To identify changes in knee joint cartilage transverse relaxation values depending on the patient's age and gender and to investigate the relationship between knee joint pathologies and the transverse relaxation time. Knee MRI images of 107 symptomatic patients with various pathologic knee conditions were analyzed retrospectively. T2 values were measured at patellar cartilage, posteromedial and posterolateral femoral cartilage adjacent to the central horn of posterior meniscus. 963 measurements were done for 107 knees MRI. Relationship of T2 values with seven features including subarticular bone marrow edema, subarticular cysts, marginal osteophytes, anterior-posterior cruciate and collateral ligament tears, posterior medial and posterior lateral meniscal tears, synovial thickening and effusion were analyzed. T2 values in all three compartments were evaluated according to age and gender. A T2 value increase correlated with age was present in all three compartments measured in the subgroup with no knee joint pathology and in all patient groups. According to the ROC curve, an increase showing a statistically significant difference was present in the patient group aged over 40 compared to the patient group aged 40 and below in all patient groups. There is a statistically difference at T2 values with and without subarticular cysts, marginal osteophytes, synovial thickening and effusion. T2 relaxation time showed a statistically significant increase in the patients with a medial meniscus tear compared to those without a tear and no statistically significant difference was found in T2 relaxation times of patients with and without a posterior lateral meniscus tear. T2 cartilage mapping on MRI provides opportunity to exhibit biochemical and structural changes related with cartilage extracellular matrix without using invasive diagnostic methods.

  8. [Liver and heart T2* measurement in secondary haemochromatosis].

    PubMed

    Barrera Portillo, M C; Uranga Uranga, M; Sánchez González, J; Alústiza Echeverría, J M; Gervás Wells, C; Guisasola Íñiguez, A

    2013-01-01

    To determine whether there is iron overload by calculating the T2* value in the liver and myocardium in patients with secondary haemochromatosis. To analyse the correlation of the values obtained with the iron levels in blood, with the liver iron concentration (LIC) calculated using magnetic resonance (MR) imaging, and the correlation between them. A total of 16 patients (13 males, 3 females), with a mean age of 61 years, were included and evaluated in the years 2008 and 2009. Fifteen of them had received multiple transfusions, and one was diagnosed with hereditary sideroblastic anaemia. The measurements included, blood ferritin, LIC by MRI, cardiac function using MRI and the T2* value by means of multi-echo sequences in the liver (TR/TE1/ΔTE/No of echos/α: 21/1,18/1.0/20/35°) and myocardium (26/1.04/0.8/30/60°). A correlation-regression analysis was performed by comparing the cardiac and liver T2* values with the ferritin, LIC and between each of them. A total of 13 patients had ferritin values greater than 1000ng/ml (median/minimum/maximum: 1762/294/3785ng/ml). An increased LIC greater than 80μmol/g (median/minimum/maximum: 125.4/41.2/241.5μmol/g) was observed in 13 patients. In all cases cardiac function was conserved, and in 15 cases the liver T2* value was less than 6.3ms. The myocardium T2* value was less than 20ms. in only one case. A high correlation was observed between the liver T2* values and the LIC (r:-0.912). The correlation was statistically significant between the liver T2* value and ferritin (r:-0.541). The correlations between myocardium T2* and ferritin, myocardium T2* and LIC, and myocardium T2* and liver T2* were not statistically significant. The liver T2* showed a high correlation with LIC and a statistically significant correlation with ferritin. No association was observed between the myocardium T2* values and ferritin in blood, the LIC or the liver T2* value. Copyright © 2011 SERAM. Published by Elsevier Espana. All rights reserved.

  9. SU-E-T-271: Direct Measurement of Tenth Value Layer Thicknesses for High Density Concretes with a Clinical Machine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tanny, S; Parsai, E; Harrell, D

    2015-06-15

    Purpose: Use of high density concrete for radiation shielding is increasing, trading cost for space savings associated with the reduced tenth value layer (TVL). Precise information on the attenuation properties of high-density concretes is not readily present in the literature. A simple approximation is to scale the TVLs from NCRP 151 according relative increase in density. Here we present measured TVLs for heavy concretes of various densities using a built-in shielding test port. Methods: Concrete densities tested range from 2.35 g cc{sup −1} (147 pcf) to 5.6 g cc{sup −1} (350 pcf). Measurements were taken using 6MV, 6FFF, and 10FFFmore » on a Varian Truebeam linear accelerator. Field sizes of 4x4, 9x9 and 30x30 cm{sup 2} were measured. A PTW 31013 Farmer chamber with a buildup cap was positioned 5.5 m from isocenter along the beam CAX. Concrete thicknesses were incremented in 5 cm intervals. Comparison TVLs were determined by scaling the NCRP 151 TVLs by the density ratio between the sample and standard density. Results: The trend from the first to equilibrium TVL was an increase in thickness, compared with MC modeling, which predicted a decrease. Measured TVLs for 6 MV were reduced by as much as 8.9 cm for TVL{sub 1} and 3.4 cm for TVL{sub E} compared to values scaled from NCRP 151. There was 1–3 mm difference in TVL between measurements done at 4x4 versus 30x30 cm{sup 2}. TVL{sub 1} for 6FFF was 1.1 cm smaller than TVL{sub 1} for 6MV, but TVL{sub E} was consistent to within 4 mm. TVL{sub 1} and TVL{sub E} for 10FFF were reduced by 8.8 and 3.7 cm from scaled NCRP values, respectively. Conclusions: We have measured the TVL thicknesses for various concretes. Simple density scaling of the values in NCRP 151 is a conservatively safe approximation, but actual TVLs may be reduced enough to eliminate some of the expense of installation. Daniel Harrell and Jim Noller are employees of Shielding Construction Solutions, Inc, the shielding construction company that

  10. Measuring Well-Being and Progress

    ERIC Educational Resources Information Center

    D'Acci, Luca

    2011-01-01

    Well-being is becoming a concept which is more and more involved in any world development consideration. A large amount of work is being carried out to study measurements of well-being, including a more holistic vision on the development and welfare of a country. This paper proposes an idea of well-being and progress being in equilibrium with each…

  11. A sensitive method for measuring protein turnover based on the measurement of 2-3H-labelled amino acids in protein.

    PubMed Central

    Humphrey, T J; Davies, D D

    1976-01-01

    A method for measuring the rate of protein degradation is described. The method measures the change in 2-3H content of protein with time by racemization of the protein hydrolysate with acetic anhydride. The 3H on C-2 of amino acids is stable in proteins but becomes labile, owing to the action of transaminases, once the amino acids are released by proteolysis. The specific measurement of 2-3H in amino acids largely overcomes problems due to compartmentation and isotope recycling and evidence to support this claim is presented. Values for the half-life of Lemna minor (duckweed) protein determined by the new method are compared with values obtained by other methods. PMID:949338

  12. Measurement of the Spectroscopic Quadrupole Moment for the 2+1 State in 10Be:. Testing AB Initio Calculations

    NASA Astrophysics Data System (ADS)

    Orce, J. N.; Djongolov, M.; Navratil, P.; Ball, G.; Garnsworthy, A. B.; Hackman, G.; Lassen, J.; Meissner, J.; Pearson, C. J.; Li, R.; Milovanovic, L.; Sjue, S. K. L.; Teigelhoefer, A.; Triambak, S.; Williams, S. J.; Falou, H. Al; Drake, T. E.; Andreoiu, C.; Cross, D.; Kshetri, R.; Finlay, P.; Garrett, P. E.; Leach, K. G.; Rand, E. T.; Sumithrarachchi, C. S.; Svensson, C. E.; Tardiff, E. R.; Wong, J.; Forssen, C.; Hayes, A. B.; Sarazin, F.; Stoyer, M. A.; Wu, C. Y.

    2013-03-01

    The highly efficient and segmented TIGRESS HPGe γ-ray array at TRIUMF has been used to perform a reorientation effect Coulomb excitation study of the 2+1 state at 3.368 MeV in 10Be. This is the first Coulomb excitation measurement that provides information on diagonal matrix elements for such a high lying first excited state from μ-ray data. With the availability of accurate lifetime data, a restriction on the diagonal < 2+1|M({E}2)|2+1> matrix element is determined. This result is compared to a no core shell model calculation with the CD-Bonn 2000 two nucleon potential.

  13. Intercomparison of six ambient [CH2O] measurement techniques

    NASA Astrophysics Data System (ADS)

    Gilpin, Tim; Apel, Eric; Fried, Alan; Wert, Bryan; Calvert, Jack; Genfa, Zhang; Dasgupta, Purnendu; Harder, Jerry W.; Heikes, Brian; Hopkins, Brian; Westberg, Hal; Kleindienst, Tad; Lee, Yin-Nan; Zhou, Xianliang; Lonneman, William; Sewell, Scott

    1997-09-01

    From May 29 to June 3, 1995 a blind intercomparison of six ambient formaldehyde measurement techniques took place at a field site near the National Center for Atmospheric Research in Boulder, Colorado. The continuous measurement methods intercompared were tunable diode laser absorption spectroscopy, (TDLAS); coil/2,4-dinitrophenylhydrazine, (CDNPH); 1,3-cyclohexanedione-diffusion scrubber (CHDDS); and the coil enzyme method (CENZ). In addition, two different cartridge methods were compared: silica gel-2,4-dinitrophenylhydrazine (DPNH) systems and a C-18-DNPH system. The intercomparison was conducted with spiked zero air (part 1) and ambient air (part 2). The CH2O standards for part 1 were calibrated by several independent methods and delivered to participants via a common glass manifold with potential trace gas interférants common to ambient air (O3, SO2, NO2, isoprene, H2O). The TDLAS system was used to confirm the absolute accuracy of the standards and served as a mission reference for part 1. The ambient phase lasted 44 hours with all participants sampling from a common glass tower. Differences between the ambient [CH2O] observed by the TDLAS and the other continuous methods were significant in some cases. For matched ambient measurement times the average ratios (±1σ) [CH2O]measured/[CH2O]TDLAS were: 0.89±0.12 (CDNPH); 1.30±0.02 (CHDDS); 0.63±0.03 (CENZ). The methods showed similar variations but different absolute values and the divergences appeared to result largely from calibration differences (no gas phase standards were used by groups other than NCAR). When the regressions of the participant [CH2O] values versus the TDLAS values, (measured in part 1), were used to normalize all of the results to the common gas phase standards of the NCAR group, the average ratios (±1σ), [CH2O]corrected/[CH2O]TDLAS for the first measurement period were much closer to unity: 1.04±0.14 (CDNPH), 1.00±0.11 (CHDDS), and 0.82±0.08 (CENZ). With the continuous methods

  14. Warm season precipitation signal in δ2 H values of wood lignin methoxyl groups from high elevation larch trees in Switzerland.

    PubMed

    Riechelmann, Dana F C; Greule, Markus; Siegwolf, Rolf T W; Anhäuser, Tobias; Esper, Jan; Keppler, Frank

    2017-10-15

    In this study, we tested stable hydrogen isotope ratios of wood lignin methoxyl groups (δ 2 H methoxyl values) as a palaeoclimate proxy in dendrochronology. This is a quite new method in the field of dendrochronology and the sample preparation is much simpler than the methods used before to measure δ 2 H values from wood. We measured δ 2 H methoxyl values in high elevation larch trees (Larix decidua Mill.) from Simplon Valley (southern Switzerland). Thirty-seven larch trees were sampled and five individuals analysed for their δ 2 H methoxyl values at annual (1971-2009) and pentadal resolution (1746-2009). The δ 2 H methoxyl values were measured as CH 3 I released upon treatment of the dried wood samples with hydroiodic acid. 10-90 μL from the head-space were injected into the gas chromatography/high-temperature conversion/isotope ratio mass spectrometry (GC/HTC-IRMS) system. Testing the climate response of the δ 2 H methoxyl values, the annually resolved series show a positive correlation of r = 0.60 with June/July precipitation. The pentadally resolved δ 2 H methoxyl series do not show any significant correlation to climate parameters. Increased precipitation during June and July, which are on average warm and relatively dry months, results in higher δ 2 H values of the xylem water and, therefore, higher δ 2 H values in the lignin methoxyl groups. Therefore, we suggest that δ 2 H methoxyl values of high elevation larch trees might serve as a summer precipitation proxy. Copyright © 2017 John Wiley & Sons, Ltd.

  15. Ergonomics Climate Assessment: A measure of operational performance and employee well-being.

    PubMed

    Hoffmeister, Krista; Gibbons, Alyssa; Schwatka, Natalie; Rosecrance, John

    2015-09-01

    Ergonomics interventions have the potential to improve operational performance and employee well-being. We introduce a framework for ergonomics climate, the extent to which an organization emphasizes and supports the design and modification of work to maximize both performance and well-being outcomes. We assessed ergonomics climate at a large manufacturing facility twice during a two-year period. When the organization used ergonomics to promote performance and well-being equally, and at a high level, employees reported less work-related pain. A larger discrepancy between measures of operational performance and employee well-being was associated with increased reports of work-related pain. The direction of this discrepancy was not significantly related to work-related pain, such that it didn't matter which facet was valued more. The Ergonomics Climate Assessment can provide companies with a baseline assessment of the overall value placed on ergonomics and help prioritize areas for improving operational performance and employee well-being. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  16. Volunteer, lay tutors' experiences of the Chronic Disease Self-Management Course: being valued and adding value.

    PubMed

    Barlow, J H; Bancroft, G V; Turner, A P

    2005-04-01

    Chronic disease is a public health issue that could be addressed, in part, by increasing the ability of individuals to better manage their condition and its consequences on a day-to-day basis. One intervention designed to facilitate this is the Chronic Disease Self Management Course (CDSMC) that is delivered by volunteer, lay tutors who themselves have a chronic disease. Although there is growing evidence of course effectiveness for participants, the experiences of tutors have been neglected. This study aims to address this omission. Telephone interviews were conducted with 11 (six male) tutors: all interviews were transcribed and thematically analysed. Being a volunteer lay-tutor was perceived to be an enjoyable and valuable experience despite the challenges associated with course delivery, such as organizational demands and managing the diverse needs of mixed groups of chronic disease participants that led to a tension between disease-specific needs and the generic approach of the course. Being valued and adding value to the lives of others were key benefits of being a volunteer tutor, along with increased confidence that they were doing something positive for others. Course delivery prompted the initiation and maintenance of tutors' own self-management behaviours.

  17. Can Preoperative Patient-reported Outcome Measures Be Used to Predict Meaningful Improvement in Function After TKA?

    PubMed

    Berliner, Jonathan L; Brodke, Dane J; Chan, Vanessa; SooHoo, Nelson F; Bozic, Kevin J

    2017-01-01

    Despite the overall effectiveness of total knee arthroplasty (TKA), a subset of patients do not experience expected improvements in pain, physical function, and quality of life as documented by patient-reported outcome measures (PROMs), which assess a patient's physical and emotional health and pain. It is therefore important to develop preoperative tools capable of identifying patients unlikely to improve by a clinically important margin after surgery. The purpose of this study was to determine if an association exists between preoperative PROM scores and patients' likelihood of experiencing a clinically meaningful change in function 1 year after TKA. A retrospective study design was used to evaluate preoperative and 1-year postoperative Knee injury and Osteoarthritis Outcome Score (KOOS) and SF-12 version 2 (SF12v2) scores from 562 patients who underwent primary unilateral TKA. This cohort represented 75% of the 750 patients who underwent surgery during that time period; a total of 188 others (25%) either did not complete PROM scores at the designated times or were lost to follow-up. Minimum clinically important differences (MCIDs) were calculated for each PROM using a distribution-based method and were used to define meaningful clinical improvement. MCID values for KOOS and SF12v2 physical component summary (PCS) scores were calculated to be 10 and 5, respectively. A receiver operating characteristic analysis was used to determine threshold values for preoperative KOOS and SF12v2 PCS scores and their respective predictive abilities. Threshold values defined the point after which the likelihood of clinically meaningful improvement began to diminish. Multivariate regression was used to control for the effect of preoperative mental and emotional health, patient attributes quantified by SF12v2 mental component summary (MCS) scores, on patients' likelihood of experiencing meaningful improvement in function after surgery. Threshold values for preoperative KOOS and SF

  18. Parents' Views Regarding the Values Aimed to be Taught in Social Studies Lessons

    ERIC Educational Resources Information Center

    Tay, Bayram; Yildirim, Kasim

    2009-01-01

    This study aimed at learning parents' ideas about the values aimed to be taught in Social Studies lessons in the 4th and 5th grades of the primary education and about values education. Study data were collected by administering "the Values Education I" and "Values Education II" questionnaire forms developed by the researchers.…

  19. Experience with novel technologies for direct measurement of atmospheric NO2

    NASA Astrophysics Data System (ADS)

    Hueglin, Christoph; Hundt, Morten; Mueller, Michael; Schwarzenbach, Beat; Tuzson, Bela; Emmenegger, Lukas

    2017-04-01

    Nitrogen dioxide (NO2) is an air pollutant that has a large impact on human health and ecosystems, and it plays a key role in the formation of ozone and secondary particulate matter. Consequently, legal limit values for NO2 are set in the EU and elsewhere, and atmospheric observation networks typically include NO2 in their measurement programmes. Atmospheric NO2 is principally measured by chemiluminescence detection, an indirect measurement technique that requires conversion of NO2 into nitrogen monoxide (NO) and finally calculation of NO2 from the difference between total nitrogen oxides (NOx) and NO. Consequently, NO2 measurements with the chemiluminescence method have a relatively high measurement uncertainty and can be biased depending on the selectivity of the applied NO2 conversion method. In the past years, technologies for direct and selective measurement of NO2 have become available, e.g. cavity attenuated phase shift spectroscopy (CAPS), cavity enhanced laser absorption spectroscopy and quantum cascade laser absorption spectrometry (QCLAS). These technologies offer clear advantages over the indirect chemiluminescence method. We tested the above mentioned direct measurement techniques for NO2 over extended time periods at atmospheric measurement stations and report on our experience including comparisons with co-located chemiluminescence instruments equipped with molybdenum as well as photolytic NO2 converters. A still open issue related to the direct measurement of NO2 is instrument calibration. Accurate and traceable reference standards and NO2 calibration gases are needed. We present results from the application of different calibration strategies based on the use of static NO2 calibration gases as well as dynamic NO2 calibration gases produced by permeation and by gas-phase titration (GPT).

  20. Measurements of Enthalpy of Sublimation of Ne, N2, O2, Ar, CO2, Kr, Xe, and H2O using a Double Paddle Oscillator.

    PubMed

    Shakeel, Hamza; Wei, Haoyan; Pomeroy, Joshua M

    2018-03-01

    We report precise experimental values of the enthalpy of sublimation (Δ H s ) of quenched condensed films of neon (Ne), nitrogen (N 2 ), oxygen (O 2 ), argon (Ar), carbon dioxide (CO 2 ), krypton (Kr), xenon (Xe), and water (H 2 O) vapor using a single consistent measurement platform. The experiments are performed well below the triple point temperature of each gas and fall in the temperature range where existing experimental data is very limited. A 6 cm 2 and 400 µm thick double paddle oscillator (DPO) with high quality factor (Q ≈ 4 × 10 5 at 298K) and high frequency stability (33 parts per billion) is utilized for the measurements. The enthalpies of sublimation are derived by measuring the rate of mass loss during temperature programmed desorption. The mass change is detected due to change in the resonance frequency of the self-tracking oscillator. Our measurements typically remain within 10% of the available literature, theory, and National Institute of Standards and Technology (NIST) Web Thermo Tables ( WTT ) values, but are performed using an internally consistent method across different gases.

  1. Can Porcine circovirus type 2 (PCV2) infection be eradicated by mass vaccination?

    PubMed

    Feng, Hua; Blanco, Gerardo; Segalés, Joaquim; Sibila, Marina

    2014-08-06

    The feasibility to eradicate Porcine circovirus type 2 (PCV2) in a conventional PCV2 infected farm by vaccinating both sows and piglets using a commercially subunit vaccine was assessed. Vaccination strategy implied that all sows, boars and gilts of the farm were vaccinated every four months, and all piglets vaccinated and revaccinated with the same vaccine at 4 and 7 weeks of age, respectively. This vaccination strategy was applied during 12 consecutive months. Blood samples from 15 piglets of 4, 8, 12, 16, 20 and 24 weeks of age and 15 sows were taken monthly PRE, DURING and POST mass vaccination strategy. From all the collected sera (n=1796), a representative proportion of them (n=1235, 69%) were analysed (n=1121 from piglets and n=114 from sows). All these samples were tested by PCV2 ELISA and PCV2 PCR (and quantitative-PCR when PCR positive). All tested sows were negative by PCR but seropositive. ELISA mean OD values of sows decreased throughout the study. Percentages of PCV2 PCR positive samples in piglets were 8% (12/150), 0.9% (6/659) and 3.5% (11/312) PRE, DURING and POST application of the mass vaccination program, respectively. ELISA mean OD values of PCV2 seropositive animals progressively decreased until the end of the mass vaccination period, but a clear seroconversion was observed after stopping such strategy. In conclusion, one year period of mass PCV2 vaccination (without implementing further farm management practices or biosafety measures) was not able to clear out PCV2 infection, and the virus became detectable again when vaccination was stopped. Copyright © 2014 Elsevier B.V. All rights reserved.

  2. Reference values of anthropometric measurements in Dutch children. The Oosterwolde Study.

    PubMed

    Gerver, W J; Drayer, N M; Schaafsma, W

    1989-03-01

    In the period 1979-1980 the following anthropometric measurements were recorded in 2351 healthy Dutch children from 0-17 years of age: height, weight, sitting height, arm span, lengths of upper-arm, lower-arm and hand, tibial length, foot length, biacromial diameter, biiliacal diameter, and head circumference. Corresponding percentile values were constructed on the basis of normality assumptions, the mean and standard deviation at age t being determined by a cubic spline approximation. The results are compared with other studies and given in the form of growth charts.

  3. Measurement of the electric quadrupole moments of CO2 , CO, N2 , Cl2 and BF3

    NASA Astrophysics Data System (ADS)

    Graham, C.; Imrie, D. A.; Raab, R. E.

    The electric quadrupole moments of a number of molecules have been determined from measurement of the birefringence induced in a gas by an electric field gradient. The values obtained are: carbon dioxide (- 14·27 ± 0·61)x 10-40 C m2, carbon monoxide (- 9·47 ± 0·15)x 10-40 C m2, nitrogen (- 4·65±0·08)x 10-40 C m2 and boron trifluoride (12·6±0·7)x 10-40 C m2. In the calculation of the moments for carbon monoxide and boron trifluoride the small hyperpolarizability contribution was neglected in the absence of known values. By means of the Jones calculus a detailed analysis was made of the effects of strain birefringence in the cell windows and imperfect orientation of polarizing components in the light path. This analysis led to a measurement procedure which yielded results significantly different from previously reported ones obtained with essentially the same apparatus. The probable error in the earlier procedure is identified.

  4. Stability of Teacher Value-Added Rankings across Measurement Model and Scaling Conditions

    ERIC Educational Resources Information Center

    Hawley, Leslie R.; Bovaird, James A.; Wu, ChaoRong

    2017-01-01

    Value-added assessment methods have been criticized by researchers and policy makers for a number of reasons. One issue includes the sensitivity of model results across different outcome measures. This study examined the utility of incorporating multivariate latent variable approaches within a traditional value-added framework. We evaluated the…

  5. Ground based NO2 and O3 measurements by visible spectrometer at Syowa Base (69 deg S), Antarctica

    NASA Technical Reports Server (NTRS)

    Kondo, Y.; Matthews, W. A.; Johnston, Paul V.; Hayashi, M.; Koike, M.; Iwasaka, Y.; Shimizu, A.; Budiyono, A.; Yamanouchi, T.; Aoki, S.

    1994-01-01

    The column amounts of NO2 and ozone have been measured using visible spectroscopy at Syowa Base (69 deg S) since March 1990. Ozone was also measured at the same location with a Dobson spectrometer as well as ozonesondes being flown regularly. The characteristic features of the seasonal and diurnal variations of NO2 are presented. The column ozone values from the visible spectrometers are compared with the Dobson data. The very low values of NO2 in midwinter and early spring are consistent with the conditions predicted to be needed for heterogeneous ozone destruction in early spring. In late spring and summer of 1991, NO2 amounts were considerably smaller than in 1990, presumably due to the effect of Mt. Pinatubo eruption.

  6. Precision half-life measurement of 11C: The most precise mirror transition F t value

    NASA Astrophysics Data System (ADS)

    Valverde, A. A.; Brodeur, M.; Ahn, T.; Allen, J.; Bardayan, D. W.; Becchetti, F. D.; Blankstein, D.; Brown, G.; Burdette, D. P.; Frentz, B.; Gilardy, G.; Hall, M. R.; King, S.; Kolata, J. J.; Long, J.; Macon, K. T.; Nelson, A.; O'Malley, P. D.; Skulski, M.; Strauss, S. Y.; Vande Kolk, B.

    2018-03-01

    Background: The precise determination of the F t value in T =1 /2 mixed mirror decays is an important avenue for testing the standard model of the electroweak interaction through the determination of Vu d in nuclear β decays. 11C is an interesting case, as its low mass and small QE C value make it particularly sensitive to violations of the conserved vector current hypothesis. The present dominant source of uncertainty in the 11CF t value is the half-life. Purpose: A high-precision measurement of the 11C half-life was performed, and a new world average half-life was calculated. Method: 11C was created by transfer reactions and separated using the TwinSol facility at the Nuclear Science Laboratory at the University of Notre Dame. It was then implanted into a tantalum foil, and β counting was used to determine the half-life. Results: The new half-life, t1 /2=1220.27 (26 ) s, is consistent with the previous values but significantly more precise. A new world average was calculated, t1/2 world=1220.41 (32 ) s, and a new estimate for the Gamow-Teller to Fermi mixing ratio ρ is presented along with standard model correlation parameters. Conclusions: The new 11C world average half-life allows the calculation of a F tmirror value that is now the most precise value for all superallowed mixed mirror transitions. This gives a strong impetus for an experimental determination of ρ , to allow for the determination of Vu d from this decay.

  7. Sequential Change in T2* Values of Cartilage, Meniscus, and Subchondral Bone Marrow in a Rat Model of Knee Osteoarthritis

    PubMed Central

    Tsai, Ping-Huei; Lee, Herng-Sheng; Siow, Tiing Yee; Chang, Yue-Cune; Chou, Ming-Chung; Lin, Ming-Huang; Lin, Chien-Yuan; Chung, Hsiao-Wen; Huang, Guo-Shu

    2013-01-01

    Background There is an emerging interest in using magnetic resonance imaging (MRI) T2* measurement for the evaluation of degenerative cartilage in osteoarthritis (OA). However, relatively few studies have addressed OA-related changes in adjacent knee structures. This study used MRI T2* measurement to investigate sequential changes in knee cartilage, meniscus, and subchondral bone marrow in a rat OA model induced by anterior cruciate ligament transection (ACLX). Materials and Methods Eighteen male Sprague Dawley rats were randomly separated into three groups (n = 6 each group). Group 1 was the normal control group. Groups 2 and 3 received ACLX and sham-ACLX, respectively, of the right knee. T2* values were measured in the knee cartilage, the meniscus, and femoral subchondral bone marrow of all rats at 0, 4, 13, and 18 weeks after surgery. Results Cartilage T2* values were significantly higher at 4, 13, and 18 weeks postoperatively in rats of the ACLX group than in rats of the control and sham groups (p<0.001). In the ACLX group (compared to the sham and control groups), T2* values increased significantly first in the posterior horn of the medial meniscus at 4 weeks (p = 0.001), then in the anterior horn of the medial meniscus at 13 weeks (p<0.001), and began to increase significantly in the femoral subchondral bone marrow at 13 weeks (p = 0.043). Conclusion Quantitative MR T2* measurements of OA-related tissues are feasible. Sequential change in T2* over time in cartilage, meniscus, and subchondral bone marrow were documented. This information could be potentially useful for in vivo monitoring of disease progression. PMID:24204653

  8. Cultural Value, Measurement and Policy Making

    ERIC Educational Resources Information Center

    O'Brien, Dave

    2015-01-01

    No matter what the national context, the question of how to understand the impact of government programmes, particularly in terms of value for money, has emerged as a complex problem to be solved by social scientific management. This article engages with these trends in two ways. It focuses on the UK to understand how these tools and technologies…

  9. Building the Infrastructure for Value at UCLA: Engaging Clinicians and Developing Patient-Centric Measurement.

    PubMed

    Clarke, Robin; Hackbarth, Andrew S; Saigal, Christopher; Skootsky, Samuel A

    2015-10-01

    Evolving payer and patient expectations have challenged academic health centers (AHCs) to improve the value of clinical care. Traditional quality approaches may be unable to meet this challenge. One AHC, UCLA Health, has implemented a systematic approach to delivery system redesign that emphasizes clinician engagement, a patient-centric scope, and condition-specific, clinician-guided measurement. A physician champion serves as quality officer (QO) for each clinical department/division. Each QO, with support from a central measurement team, has developed customized analytics that use clinical data to define targeted populations and measure care across the full treatment episode. From October 2012 through June 2015, the approach developed rapidly. Forty-three QOs are actively redesigning care delivery protocols within their specialties, and 95% of the departments/divisions have received a customized measure report for at least one patient population. As an example of how these analytics promote systematic redesign, the authors discuss how Department of Urology physicians have used these new measures, first, to better understand the relationship between clinical practice and outcomes for patients with benign prostatic hyperplasia and, then, to work toward reducing unwarranted variation. Physicians have received these efforts positively. Early outcome data are encouraging. This infrastructure of engaged physicians and targeted measurement is being used to implement systematic care redesign that reliably achieves outcomes that are meaningful to patients and clinicians-incorporating both clinical and cost considerations. QOs are using an approach, for multiple newly launched projects, to identify, test, and implement value-oriented interventions tailored to specific patient populations.

  10. Measuring the Value of Public Health Systems: The Disconnect Between Health Economists and Public Health Practitioners

    PubMed Central

    Jacobson, Peter D.; Palmer, Jennifer A.

    2008-01-01

    We investigated ways of defining and measuring the value of services provided by governmental public health systems. Our data sources included literature syntheses and qualitative interviews of public health professionals. Our examination of the health economic literature revealed growing attempts to measure value of public health services explicitly, but few studies have addressed systems or infrastructure. Interview responses demonstrated no consensus on metrics and no connection to the academic literature. Key challenges for practitioners include developing rigorous, data-driven methods and skilled staff; being politically willing to base allocation decisions on economic evaluation; and developing metrics to capture “intangibles” (e.g., social justice and reassurance value). Academic researchers evaluating the economics of public health investments should increase focus on the working needs of public health professionals. PMID:18923123

  11. Exhaled nitric oxide measurements in the first 2 years of life: methodological issues, clinical and epidemiological applications

    PubMed Central

    Gabriele, Carmelo; de Benedictis, Fernando M; de Jongste, Johan C

    2009-01-01

    Fractional exhaled nitric oxide (FeNO) is a useful tool to diagnose and monitor eosinophilic bronchial inflammation in asthmatic children and adults. In children younger than 2 years of age FeNO has been successfully measured both with the tidal breathing and with the single breath techniques. However, there are a number of methodological issues that need to be addressed in order to increase the reproducibility of the FeNO measurements within and between infants. Indeed, a standardized method to measure FeNO in the first 2 years of life would be extremely useful in order to meaningfully interpret FeNO values in this age group. Several factors related to the measurement conditions have been found to influence FeNO, such as expiratory flow, ambient NO and nasal contamination. Furthermore, the exposure to pre- and postnatal risk factors for respiratory morbidity has been shown to influence FeNO values. Therefore, these factors should always be assessed and their association with FeNO values in the specific study population should be evaluated and, eventually, controlled for. There is evidence consistently suggesting that FeNO is increased in infants with family history of atopy/atopic diseases and in infants with recurrent wheezing. These findings could support the hypothesis that eosinophilic bronchial inflammation is present at an early stage in those infants at increased risk of developing persistent respiratory symptoms and asthma. Furthermore, it has been shown that FeNO measurements could represent a useful tool to assess bronchial inflammation in other airways diseases, such as primary ciliary dyskinesia, bronchopulmonary dysplasia and cystic fibrosis. Further studies are needed in order to improve the reproducibility of the measurements, and large prospective studies are warranted in order to evaluate whether FeNO values measured in the first years of life can predict the future development of asthma or other respiratory diseases. PMID:19712438

  12. Development of a Singlet Oxygen Absorption Capacity (SOAC) Assay Method. Measurements of the SOAC Values for Carotenoids and α-Tocopherol in an Aqueous Triton X-100 Micellar Solution.

    PubMed

    Mukai, Kazuo; Ouchi, Aya; Azuma, Nagao; Takahashi, Shingo; Aizawa, Koichi; Nagaoka, Shin-Ichi

    2017-02-01

    Recently, a new assay method for the quantification of the singlet oxygen absorption capacity (SOAC) of antioxidants (AOs) and food extracts in homogeneous organic solvents was proposed. In this study, second-order rate constants (k Q ) for the reaction of singlet oxygen ( 1 O 2 ) with eight different carotenoids (Cars) and α-tocopherol (α-Toc) were measured in an aqueous Triton X-100 (5.0 wt %) micellar solution (pH 7.4, 35 °C), which was used as a simple model of biomembranes. The k Q and relative SOAC values were measured using ultraviolet-visible (UV-vis) spectroscopy. The UV-vis absorption spectra of Cars and α-Toc were measured in both a micellar solution and chloroform, to investigate the effect of solvent on the k Q and SOAC values. Furthermore, decay rates (k d ) of 1 O 2 were measured in 0.0, 1.0, 3.0, and 5.0 wt % micellar solutions (pH 7.4), using time-resolved near-infrared fluorescence spectroscopy, to determine the absolute k Q values of the AOs. The results obtained demonstrate that the k Q values of AOs in homogeneous and heterogeneous solutions vary notably depending on (i) the polarity [dielectric constant (ε)] of the reaction field between AOs and 1 O 2 , (ii) the local concentration of AOs, and (iii) the mobility of AOs in solution. In addition, the k Q and relative SOAC values obtained for the Cars in a heterogeneous micellar solution differ remarkably from those in homogeneous organic solvents. Measurements of k Q and SOAC values in a micellar solution may be useful for evaluating the 1 O 2 quenching activity of AOs in biological systems.

  13. Women Like Being Valued for Sex, as Long as it is by a Committed Partner.

    PubMed

    Meltzer, Andrea L; McNulty, James K; Maner, Jon K

    2017-02-01

    How do women respond to being valued for sex by their partners? Although research supporting objectification theory suggests that women's reactions to sexual valuation are primarily negative, a separate body of research indicates that women expend significant effort to enhance their sexual appeal. Evolutionary perspectives suggest that whether women are more or less satisfied with partners who value them for sex may depend on how committed those partners are. Being sexually valued by a relatively uncommitted partner may violate women's desire to avoid short-term sexual relationships and thus may be negatively associated with relationship satisfaction. In contrast, being sexually valued by a highly committed partner may positively influence women's relationship satisfaction because it signals to them that they have successfully attracted a long-term relationship partner. Two studies of newly married couples supported these predictions. In Study 1 (N = 109), husbands' sexual valuation was positively associated with marital satisfaction among wives who perceived that those husbands were highly committed, but negatively associated with marital satisfaction among wives who perceived that those husbands were relatively less committed. Study 2 (N = 99) revealed the same pattern for wives (but not husbands) using a likely manifestation of sexual valuation-engaging in frequent sex. These findings join others to demonstrate that interpersonal processes do not have universally positive or negative implications for relationships; rather, their implications depend on the context in which they occur, including contexts that were reproductively beneficial or costly throughout evolutionary history.

  14. Usefulness of Pulse Oximeter That Can Measure SpO2 to One Digit After Decimal Point.

    PubMed

    Yamamoto, Akihiro; Burioka, Naoto; Eto, Aritoshi; Amisaki, Takashi; Shimizu, Eiji

    2017-06-01

    Pulse oximeters are used to noninvasively measure oxygen saturation in arterial blood (SaO 2 ). Although arterial oxygen saturation measured by pulse oximeter (SpO 2 ) is usually indicated in 1% increments, the value of SaO 2 from arterial blood gas analysis is not an integer. We have developed a new pulse oximeter that can measure SpO 2 to one digit after the decimal point. The values of SpO 2 from the newly developed pulse oximeter are highly correlated with the values of SaO 2 from arterial blood gas analysis (SpO 2 = 0.899 × SaO 2 + 9.944, r = 0.887, P < 0.0001). This device may help improve the evaluation of pathological conditions in patients.

  15. Valuing Flexibility Phase 2

    DTIC Science & Technology

    2012-10-29

    longer by adding an additional mid section8.  Radio Frequency Identification (RFID): This established technology is being considered for use to...MONITOR’S ACRONYM(S) 11 . SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release; distribution unlimited...Introduction ............................................................................................ 11 3 A Taxonomy of Methods for Valuing

  16. Valuing Flexibility. Phase 2

    DTIC Science & Technology

    2012-10-29

    modules and their interfaces are designed such that the ship can be made longer by adding an additional mid section8.  Radio Frequency ...MONITOR’S ACRONYM(S) 11 . SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release, distribution... 11 3 A Taxonomy of Methods for Valuing Flexibility

  17. The Values Adolescents Aspire to, Their Well-Being and the Values Parents Aspire to for Their Children

    ERIC Educational Resources Information Center

    Casas, Ferran; Figuer, Cristina; Gonzalez, Monica; Malo, Sara

    2007-01-01

    This paper presents a study of the relationship between the psychological well-being of Spanish adolescents from 12 to 16 years old and the values they aspire to for the future (N = 1,618). Adolescents' well-being is explored through (a) their satisfaction with 19 specific life domains, (b) the Personal Well-Being Index (Cummins, "Social…

  18. GESFIDE-PROPELLER approach for simultaneous R2 and R2* measurements in the abdomen.

    PubMed

    Jin, Ning; Guo, Yang; Zhang, Zhuoli; Zhang, Longjiang; Lu, Guangming; Larson, Andrew C

    2013-12-01

    To investigate the feasibility of combining GESFIDE with PROPELLER sampling approaches for simultaneous abdominal R2 and R2* mapping. R2 and R2* measurements were performed in 9 healthy volunteers and phantoms using the GESFIDE-PROPELLER and the conventional Cartesian-sampling GESFIDE approaches. Images acquired with the GESFIDE-PROPELLER sequence effectively mitigated the respiratory motion artifacts, which were clearly evident in the images acquired using the conventional GESFIDE approach. There was no significant difference between GESFIDE-PROPELLER and reference MGRE R2* measurements (p=0.162) whereas the Cartesian-sampling based GESFIDE methods significantly overestimated R2* values compared to MGRE measurements (p<0.001). The GESFIDE-PROPELLER sequence provided high quality images and accurate abdominal R2 and R2* maps while avoiding the motion artifacts common to the conventional Cartesian-sampling GESFIDE approaches. © 2013 Elsevier Inc. All rights reserved.

  19. GESFIDE-PROPELLER Approach for Simultaneous R2 and R2* Measurements in the Abdomen

    PubMed Central

    Jin, Ning; Guo, Yang; Zhang, Zhuoli; Zhang, Longjiang; Lu, Guangming; Larson, Andrew C.

    2013-01-01

    Purpose To investigate the feasibility of combining GESFIDE with PROPELLER sampling approaches for simultaneous abdominal R2 and R2* mapping. Materials and Methods R2 and R2* measurements were performed in 9 healthy volunteers and phantoms using the GESFIDE-PROPELLER and the conventional Cartesian-sampling GESFIDE approaches. Results Images acquired with the GESFIDE-PROPELLER sequence effectively mitigated the respiratory motion artifacts, which were clearly evident in the images acquired using the conventional GESFIDE approach. There were no significant difference between GESFIDE-PROPELLER and reference MGRE R2* measurements (p = 0.162) whereas the Cartesian-sampling based GESFIDE methods significantly overestimated R2* values compared to MGRE measurements (p < 0.001). Conclusion The GESFIDE-PROPELLER sequence provided high quality images and accurate abdominal R2 and R2* maps while avoiding the motion artifacts common to the conventional Cartesian-sampling GESFIDE approaches. PMID:24041478

  20. Measuring CO 2 and N 2 O Mass Transfer into GAP-1 CO 2 –Capture Solvents at Varied Water Loadings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Whyatt, Greg A.; Zwoster, Andy; Zheng, Feng

    This paper investigates the CO 2 and N 2 O absorption behavior in the water-lean gamma amino propyl (GAP)-1/TEG solvent system using a wetted-wall contactor. Testing was performed on a blend of GAP-1 aminosilicone in triethylene glycol at varied water loadings in the solvent. Measurements were made with CO 2 and N 2 O at representative lean (0.04 mol CO 2/mol alkalinity), middle (0.13 mol CO 2 /mol alkalinity) and rich (0.46 mol CO 2 /mol alkalinity) solvent loadings at 0, 5, 10 and 15 wt% water loadings at 40, 60 and 80C° and N 2 O at (0.08-0.09 molmore » CO 2 /mol alkalinity) at 5 wt% water at 40, 60 and 80C°. CO 2 flux was found to be non-linear with respect to log mean pressure driving force (LMPD). Liquid-film mass transfer coefficients (k'g) were calculated by subtracting the gas film resistance (determined from a correlation from literature) from the overall mass transfer measurement. The resulting k'g values for CO 2 and N 2 O in GAP-1/TEG mixtures were found to be higher than that of 5M aqueous monoethanolamine under comparable driving force albeit at higher solvent viscosities. The k'g values for CO 2 were also found to decrease with increasing solvent water content and increase with a decrease in temperature. These observations indicate that mass transfer of CO 2 in GAP-1/TEG is linked to the physical solubility of CO 2 , which is higher in organic solvents compared to water. This paper expands on the understanding of the unique mass transfer behavior and kinetics of CO 2 capture in water-lean solvents.« less

  1. Mid-IR hyperspectral imaging of laminar flames for 2-D scalar values.

    PubMed

    Rhoby, Michael R; Blunck, David L; Gross, Kevin C

    2014-09-08

    This work presents a new emission-based measurement which permits quantification of two-dimensional scalar distributions in laminar flames. A Michelson-based Fourier-transform spectrometer coupled to a mid-infrared camera (1.5 μm to 5.5 μm) obtained 256 × 128pixel hyperspectral flame images at high spectral (δν̃ = 0.75cm(−1)) and spatial (0.52 mm) resolutions. The measurements revealed line and band emission from H2O, CO2, and CO. Measurements were collected from a well-characterized partially-premixed ethylene (C2H4) flame produced on a Hencken burner at equivalence ratios, Φ, of 0.8, 0.9, 1.1, and 1.3. After describing the instrument and novel calibration methodology, analysis of the flames is presented. A single-layer, line-by-line radiative transfer model is used to retrieve path-averaged temperature, H2O, CO2 and CO column densities from emission spectra between 2.3 μm to 5.1 μm. The radiative transfer model uses line intensities from the latest HITEMP and CDSD-4000 spectroscopic databases. For the Φ = 1.1 flame, the spectrally estimated temperature for a single pixel 10 mm above burner center was T = (2318 ± 19)K, and agrees favorably with recently reported laser absorption measurements, T = (2348 ± 115)K, and a NASA CEA equilibrium calculation, T = 2389K. Near the base of the flame, absolute concentrations can be estimated, and H2O, CO2, and CO concentrations of (12.5 ± 1.7) %, (10.1 ± 1.0) %, and (3.8 ± 0.3) %, respectively, compared favorably with the corresponding CEA values of 12.8%, 9.9% and 4.1%. Spectrally-estimated temperatures and concentrations at the other equivalence ratios were in similar agreement with measurements and equilibrium calculations. 2-D temperature and species column density maps underscore the Φ-dependent chemical composition of the flames. The reported uncertainties are 95% confidence intervals and include both statistical fit errors and the propagation of systematic calibration errors using a Monte Carlo

  2. How rational should bioethics be? The value of empirical approaches.

    PubMed

    Alvarez, A A

    2001-10-01

    Rational justification of claims with empirical content calls for empirical and not only normative philosophical investigation. Empirical approaches to bioethics are epistemically valuable, i.e., such methods may be necessary in providing and verifying basic knowledge about cultural values and norms. Our assumptions in moral reasoning can be verified or corrected using these methods. Moral arguments can be initiated or adjudicated by data drawn from empirical investigation. One may argue that individualistic informed consent, for example, is not compatible with the Asian communitarian orientation. But this normative claim uses an empirical assumption that may be contrary to the fact that some Asians do value and argue for informed consent. Is it necessary and factual to neatly characterize some cultures as individualistic and some as communitarian? Empirical investigation can provide a reasonable way to inform such generalizations. In a multi-cultural context, such as in the Philippines, there is a need to investigate the nature of the local ethos before making any appeal to authenticity. Otherwise we may succumb to the same ethical imperialism we are trying hard to resist. Normative claims that involve empirical premises cannot be reasonable verified or evaluated without utilizing empirical methods along with philosophical reflection. The integration of empirical methods to the standard normative approach to moral reasoning should be reasonably guided by the epistemic demands of claims arising from cross-cultural discourse in bioethics.

  3. Sustaining the Essence: Community Values, Knowledges, and Ways of Being

    ERIC Educational Resources Information Center

    Haynes Writer, Jeanette

    2017-01-01

    Values, knowledges, and ways of being are the essences and cultural imperatives for tribal nation students and communities, and they sustain the tribal nations' continuance as distinct Peoples. After discussing historical and ongoing colonialist oppression, the author urges educators to form partnerships with communities to foster students'…

  4. An interval-valued 2-tuple linguistic group decision-making model based on the Choquet integral operator

    NASA Astrophysics Data System (ADS)

    Liu, Bingsheng; Fu, Meiqing; Zhang, Shuibo; Xue, Bin; Zhou, Qi; Zhang, Shiruo

    2018-01-01

    The Choquet integral (IL) operator is an effective approach for handling interdependence among decision attributes in complex decision-making problems. However, the fuzzy measures of attributes and attribute sets required by IL are difficult to achieve directly, which limits the application of IL. This paper proposes a new method for determining fuzzy measures of attributes by extending Marichal's concept of entropy for fuzzy measure. To well represent the assessment information, interval-valued 2-tuple linguistic context is utilised to represent information. Then, we propose a Choquet integral operator in an interval-valued 2-tuple linguistic environment, which can effectively handle the correlation between attributes. In addition, we apply these methods to solve multi-attribute group decision-making problems. The feasibility and validity of the proposed operator is demonstrated by comparisons with other models in illustrative example part.

  5. 7Be solar neutrino measurement with KamLAND

    NASA Astrophysics Data System (ADS)

    Gando, A.; Gando, Y.; Hanakago, H.; Ikeda, H.; Inoue, K.; Ishidoshiro, K.; Ishikawa, H.; Kishimoto, Y.; Koga, M.; Matsuda, R.; Matsuda, S.; Mitsui, T.; Motoki, D.; Nakajima, K.; Nakamura, K.; Obata, A.; Oki, A.; Oki, Y.; Otani, M.; Shimizu, I.; Shirai, J.; Suzuki, A.; Tamae, K.; Ueshima, K.; Watanabe, H.; Xu, B. D.; Yamada, S.; Yamauchi, Y.; Yoshida, H.; Kozlov, A.; Takemoto, Y.; Yoshida, S.; Grant, C.; Keefer, G.; McKee, D. W.; Piepke, A.; Banks, T. I.; Bloxham, T.; Freedman, S. J.; Fujikawa, B. K.; Han, K.; Hsu, L.; Ichimura, K.; Murayama, H.; O'Donnell, T.; Steiner, H. M.; Winslow, L. A.; Dwyer, D.; Mauger, C.; McKeown, R. D.; Zhang, C.; Berger, B. E.; Lane, C. E.; Maricic, J.; Miletic, T.; Learned, J. G.; Sakai, M.; Horton-Smith, G. A.; Tang, A.; Downum, K. E.; Tolich, K.; Efremenko, Y.; Kamyshkov, Y.; Perevozchikov, O.; Karwowski, H. J.; Markoff, D. M.; Tornow, W.; Detwiler, J. A.; Enomoto, S.; Heeger, K.; Decowski, M. P.; KamLAND Collaboration

    2015-11-01

    We report a measurement of the neutrino-electron elastic scattering rate of 862 keV 7Be solar neutrinos based on a 165.4 kt d exposure of KamLAND. The observed rate is 582 ±94 (kt d)-1, which corresponds to an 862-keV 7Be solar neutrino flux of (3.26 ±0.52 ) ×109cm-2s-1 , assuming a pure electron-flavor flux. Comparing this flux with the standard solar model prediction and further assuming three-flavor mixing, a νe survival probability of 0.66 ±0.15 is determined from the KamLAND data. Utilizing a global three-flavor oscillation analysis, we obtain a total 7Be solar neutrino flux of (5.82 ±1.02 ) ×109cm-2s-1 , which is consistent with the standard solar model predictions.

  6. The 24 GHz measurements of 2.2 lambda conical horn antennas illuminating a conducting sheet

    NASA Technical Reports Server (NTRS)

    Cross, A. E.; Marshall, R. E.; Hearn, C. P.; Neece, R. T.

    1993-01-01

    Monostatic reflection-coefficient magnitude, absolute value of Gamma, measurements occurring between a radiating horn and a metal reflecting plate are presented for a family of three 2.2 lambda diameter conical horn antennas. The three horns have different aperture phase deviations: 6 deg, 22.5 deg, and 125 deg. Measurements of the magnitude of absolute value of Gamma as a function of horn-plate separation (d) extend from an effective antenna aperture short (d = O) to beyond the far-field boundary (d = 2D(sup 2)/lambda, where D is the antenna diameter). Measurement data are presented with various physical environments for each of the horns. Measured scalar data are compared with theoretical data from two models, a numerical model for a circular waveguide aperture in a ground plane and a scalar diffraction theory model. This work was conducted in support of the development effort for a spaceborne multifrequency microwave reflectometer designed to accurately determine the distance from a space vehicle's surface to a reflecting plasma boundary. The metal reflecting plate was used to simulate the RF reflectivity of a critically dense plasma. The resulting configuration, a ground plane mounted aperture facing a reflecting plane in close proximity, produces a strong interaction between the ground plane and the reflecting plate, especially at integral half-wavelength separations. The transition coefficient is characterized by large amplitude variations.

  7. Valuation of Green Walls and Green Roofs as Soundscape Measures: Including Monetised Amenity Values Together with Noise-attenuation Values in a Cost-benefit Analysis of a Green Wall Affecting Courtyards

    PubMed Central

    Veisten, Knut; Smyrnova, Yuliya; Klæboe, Ronny; Hornikx, Maarten; Mosslemi, Marjan; Kang, Jian

    2012-01-01

    Economic unit values of soundscape/acoustic effects have been based on changes in the number of annoyed persons or on decibel changes. The normal procedure has been the application of these unit values to noise-attenuation measures affecting the noisier façade of a dwelling. Novel modular vegetation-based soundscape measures, so-called green walls, might be relevant for both noisy and quieter areas. Moreover, their benefits will comprise noise attenuation as well as non-acoustic amenity effects. One challenge is to integrate the results of some decades of non-acoustic research on the amenity value of urban greenery into design of the urban sound environment, and incorporate these non-acoustic properties in the overall economic assessment of noise control and overall sound environment improvement measures. Monetised unit values for green walls have been included in two alternative cases, or demonstration projects, of covering the entrances to blocks of flats with a green wall. Since these measures improve the noise environment on the quiet side of the dwellings and courtyards, not the most exposed façade, adjustment factors to the nominal quiet side decibel reductions to arrive at an estimate of the equivalent overall acoustic improvement have been applied. A cost-benefit analysis of the green wall case indicates that this measure is economically promising, when valuing the noise attenuation in the quieter area and adding the amenity/aesthetic value of the green wall. PMID:23202816

  8. Reference values for developing responsive functional outcome measures across the lifespan.

    PubMed

    McKay, Marnee J; Baldwin, Jennifer N; Ferreira, Paulo; Simic, Milena; Vanicek, Natalie; Burns, Joshua

    2017-04-18

    To generate a reference dataset of commonly performed functional outcome measures in 1,000 children and adults and investigate the influence of demographic, anthropometric, strength, and flexibility characteristics. Twelve functional outcome measures were collected from 1,000 healthy individuals aged 3-101 years: 6-minute walk test, 30-second chair stand test, timed stairs test, long jump, vertical jump, choice stepping reaction time, balance (Star Excursion Balance Test, tandem stance eyes open and closed, single-leg stance eyes closed), and dexterity (9-hole peg test, Functional Dexterity Test). Correlation and multiple regression analyses were performed to identify factors independently associated with each measure. Age- and sex-stratified reference values for functional outcome measures were generated. Functional performance increased through childhood and adolescence, plateaued during adulthood, and declined in older adulthood. While balance did not differ between the sexes, male participants generally performed better at gross motor tasks while female participants performed better at dexterous tasks. Height was the most consistent correlate of functional performance in children, while lower limb muscle strength was a major determinant in adolescents and adults. In older adults, age, lower limb strength, and joint flexibility explained up to 63% of the variance in functional measures. These normative reference values provide a framework to accurately track functional decline associated with neuromuscular disorders and assist development and validation of responsive outcome measures for therapeutic trials. © 2017 American Academy of Neurology.

  9. The added value of measuring thumb and finger strength when comparing strength measurements in hypoplastic thumb patients.

    PubMed

    Molenaar, H M Ties; Selles, Ruud W; de Kraker, Marjolein; Stam, Henk J; Hovius, Steven E R

    2013-10-01

    When interventions to the hand are aimed at improving function of specific fingers or the thumb, the RIHM (Rotterdam Intrinsic Hand Myometer) is a validated tool and offers more detailed information to assess strength of the involved joints besides grip and pinch measurements. In this study, strength was measured in 65 thumbs in 40 patients diagnosed with thumb hypoplasia. These 65 thumbs were classified according to Blauth. Longitudinal radial deficiencies were also classified. The strength measurements comprised of grip, tip, tripod and key pinch. Furthermore palmar abduction and opposition of the thumb as well as abduction of the index and little finger were measured with the RIHM. For all longitudinal radial deficiency patients, grip and pinch strength as well as palmar abduction and thumb opposition were significantly lower than reference values (P<0.001). However, strength in the index finger abduction and the little finger abduction was maintained or decreased to a lesser extent according to the degree of longitudinal radial deficiency. All strength values decreased with increasing Blauth-type. Blauth-type II hands (n=15) with flexor digitorum superficialis 4 opposition transfer including stabilization of the metacarpophalangeal joint showed a trend toward a higher opposition strength without reaching statistical significance (P=0.094),however compared to non-operated Blauth-type II hands (n=6) they showed a lower grip strength (P=0.019). The RIHM is comparable in accuracy to other strength dynamometers. Using the RIHM, we were able to illustrate strength patterns on finger-specific level, showing added value when evaluating outcome in patients with hand related problems. © 2013.

  10. A quantum inspired model of radar range and range-rate measurements with applications to weak value measurements

    NASA Astrophysics Data System (ADS)

    Escalante, George

    2017-05-01

    Weak Value Measurements (WVMs) with pre- and post-selected quantum mechanical ensembles were proposed by Aharonov, Albert, and Vaidman in 1988 and have found numerous applications in both theoretical and applied physics. In the field of precision metrology, WVM techniques have been demonstrated and proven valuable as a means to shift, amplify, and detect signals and to make precise measurements of small effects in both quantum and classical systems, including: particle spin, the Spin-Hall effect of light, optical beam deflections, frequency shifts, field gradients, and many others. In principal, WVM amplification techniques are also possible in radar and could be a valuable tool for precision measurements. However, relatively limited research has been done in this area. This article presents a quantum-inspired model of radar range and range-rate measurements of arbitrary strength, including standard and pre- and post-selected measurements. The model is used to extend WVM amplification theory to radar, with the receive filter performing the post-selection role. It is shown that the description of range and range-rate measurements based on the quantum-mechanical measurement model and formalism produces the same results as the conventional approach used in radar based on signal processing and filtering of the reflected signal at the radar receiver. Numerical simulation results using simple point scatterrer configurations are presented, applying the quantum-inspired model of radar range and range-rate measurements that occur in the weak measurement regime. Potential applications and benefits of the quantum inspired approach to radar measurements are presented, including improved range and Doppler measurement resolution.

  11. The relationship of live animal muscular and skeletal scores, ultrasound measurements and carcass classification scores with carcass composition and value in steers.

    PubMed

    Conroy, S B; Drennan, M J; Kenny, D A; McGee, M

    2009-11-01

    This study examined the relationship of muscular and skeletal scores and ultrasound measurements in the live animal, and carcass conformation and fat scores with carcass composition and value using 336 steers, slaughtered at 2 years of age. Live animal scores and measurements were recorded at 8 to 12 months of age and pre-slaughter. Following slaughter, each carcass was classified for conformation and fatness and the right side dissected into meat, fat and bone. Carcass conformation scores and fat scores were both measured on a continuous 15-point scale and ranged from 2.0 to 12.0 and from 2.8 to 13.3, respectively. Pre-slaughter muscular scores showed positive correlations (P < 0.001) ranging from 0.31 to 0.86 with carcass meat proportion, proportion of high-value cuts in the carcass, conformation score and carcass value, significant negative correlations with carcass fat (r = -0.13) and bone (r = -0.81) proportions, and generally low non-significant relationships with the proportion of high-value cuts in meat and carcass fat score. Pre-slaughter ultrasound muscle depth and carcass conformation score showed similar correlations with carcass traits to those using the pre-slaughter muscular scoring procedure. Pre-slaughter ultrasound fat depth showed positive correlations (P < 0.001) with carcass fat proportion (r = 0.59) and fat score (r = 0.63), and significant negative correlations (-0.23 to -0.50) with carcass meat and bone proportions, high-value cuts in the carcass and in meat, and carcass value. Pre-slaughter skeletal scores generally showed poor correlations ranging from -0.38 to 0.52 with the various carcass traits. Corresponding correlations (-0.26 to 0.44) involving records collected at 8 to 12 months of age were lower than those using pre-slaughter records. A one-unit increase in carcass conformation score increased carcass meat proportion and value by 11.2 g/kg and 5.6 cents/kg, respectively. Corresponding values for fat score were -8.2 g/kg and -5

  12. Direct Measurement of the Mass Difference of 163Ho and 163Dy Solves the Q -Value Puzzle for the Neutrino Mass Determination

    NASA Astrophysics Data System (ADS)

    Eliseev, S.; Blaum, K.; Block, M.; Chenmarev, S.; Dorrer, H.; Düllmann, Ch. E.; Enss, C.; Filianin, P. E.; Gastaldo, L.; Goncharov, M.; Köster, U.; Lautenschläger, F.; Novikov, Yu. N.; Rischka, A.; Schüssler, R. X.; Schweikhard, L.; Türler, A.

    2015-08-01

    The atomic mass difference of 163 and 163Dy has been directly measured with the Penning-trap mass spectrometer SHIPTRAP applying the novel phase-imaging ion-cyclotron-resonance technique. Our measurement has solved the long-standing problem of large discrepancies in the Q value of the electron capture in 163Ho determined by different techniques. Our measured mass difference shifts the current Q value of 2555(16) eV evaluated in the Atomic Mass Evaluation 2012 [G. Audi et al., Chin. Phys. C 36, 1157 (2012)] by more than 7 σ to 2833 (30stat)(15sys) eV /c2 . With the new mass difference it will be possible, e.g., to reach in the first phase of the ECHo experiment a statistical sensitivity to the neutrino mass below 10 eV, which will reduce its present upper limit by more than an order of magnitude.

  13. Determination of threshold value of soil water content for field and vegetable plants with lysimeter measurements

    NASA Astrophysics Data System (ADS)

    Knoblauch, S.

    2009-04-01

    Both the potential water consumption of plants and their ability to withdraw soil water are necessary in order to estimate actual evapotranspiration and to predict irrigation timing and amount. In relating to root water uptake the threshold value at which plants reducing evapotranspiration is an important parameter. Since transpiration is linearly correlated to dry matter production, under the condition that the AET/PET-Quotient is smaller than 1.0 (de Wit 1958, Tanner & Sinclair 1983), the dry matter production begins to decline too. Plants respond to drought with biochemical, physiological and morphological modifications in order to avoid damages, for instance by increasing the root water uptake. The objective of the study is to determine threshold values of soil water content and pressure head respectively for different field and vegetable plants with lysimeter measurements and to derive so called reduction functions. Both parameter, potenzial water demand in several growth stages and threshold value of soil water content or pressure head can be determined with weighable field lysimeter. The threshold value is reached, when the evapotranspiration under natural rainfall condition (AET) drop clearly (0.8 PET) below the value under well watered condition (PET). Basis for the presented results is the lysimeter plant Buttelstedt of the Thuringian State Institute of Agriculture. It consist of two lysimeter cellars, each with two weighable monolithic lysimeters. The lysimeter are 2.5 m deep with a surface area of 2 m2 to allow a non-restrictive root growth and to arrange a representative number of plants. The weighing accuracy amounts to 0.05 mm. The percolating water is collected by ceramic suction cups with suction up to 0.3 MPa at a depth of 2.3 m. The soil water content is measured by using neutron probe. One of the two lysimeter cellars represents the will irrigated, the other one the non irrigated and/or reduced irrigated part of field. The soil is a Haplic

  14. Bymixer system can measure O2 uptake and CO2 elimination in the anesthesia circle circuit.

    PubMed

    Rosenbaum, Abraham; Kirby, Christopher W; Breen, Peter H

    2007-06-01

    The ability to measure carbon dioxide elimination (Vco(2)), oxygen uptake (Vo(2)), and R (respiratory exchange ratio, Vco(2)/Vo(2)) during anesthesia may help the non-invasive detection of critical events (e.g., abrupt decrease in cardiac output) and metabolic upset (e.g., onset of anaerobic metabolism). We have developed a new clinical bymixer (inline mixing chamber) that can measure mixed inspired and expired gas fractions in the anesthesia circle circuit. The addition of a standard anesthesia gas analyzer and flowmeter, and a new airway temperature and humidity sensor, allow determinations of Vco(2) and Vo(2) at the airway opening of the circle circuit. Over a range of tidal volume and frequency, Vco(2) and Vo(2) were compared to reference values generated by the combustion of metered liquid ethanol in a new metabolic lung simulator. By linear regression, bymixer-flow measurements of Vco(2) (slope = 1.02, Y-intercept = -5.31, coefficient of determination, R(2) = 0.998) and Vo(2) (slope = 1.05, Y-intercept = -4.34, R(2) = 0.993) correlated closely to the reference values generated by the metabolic lung simulator. Limits of agreement analysis generated percent errors (mean +/- 1.96 SD) of -1.2 +/- 7.2% for Vco(2) and 2.5 +/- 9.8% for Vo(2). The new clinical bymixer is compact, lightweight, disposable, inexpensive, and has a fast and adjustable response time (time constant about 14 sec). Anesthesia circle circuit integrity is maintained. Bymixer-flow measurements of Vco(2) and Vo(2) are accurate and may add to clinical monitoring under anesthesia and surgery.

  15. Bayes' theorem application in the measure information diagnostic value assessment

    NASA Astrophysics Data System (ADS)

    Orzechowski, Piotr D.; Makal, Jaroslaw; Nazarkiewicz, Andrzej

    2006-03-01

    The paper presents Bayesian method application in the measure information diagnostic value assessment that is used in the computer-aided diagnosis system. The computer system described here has been created basing on the Bayesian Network and is used in Benign Prostatic Hyperplasia (BPH) diagnosis. The graphic diagnostic model enables to juxtapose experts' knowledge with data.

  16. Validity of Postexercise Measurements to Estimate Peak VO2 in 200-m and 400-m Maximal Swims.

    PubMed

    Rodríguez, Ferran A; Chaverri, Diego; Iglesias, Xavier; Schuller, Thorsten; Hoffmann, Uwe

    2017-06-01

    To assess the validity of postexercise measurements to estimate oxygen uptake (V˙O 2 ) during swimming, we compared V˙O 2 measured directly during an all-out 200-m swim with measurements estimated during 200-m and 400-m maximal tests using several methods, including a recent heart rate (HR)/V˙O 2 modelling procedure. 25 elite swimmers performed a 200-m maximal swim where V˙O 2 was measured using a swimming snorkel connected to a gas analyzer. The criterion variable was V˙O 2 in the last 20 s of effort, which was compared with the following V˙O 2peak estimates: 1) first 20-s average; 2) linear backward extrapolation (BE) of the first 20 and 30 s, 3×20-s, 4×20-s, and 3×20-s or 4×20-s averages; 3) semilogarithmic BE at the same intervals; and 4) predicted V˙O 2peak using mathematical modelling of 0-20 s and 5-20 s during recovery. In 2 series of experiments, both of the HR/V˙O 2 modelled values most accurately predicted the V˙O 2peak (mean ∆=0.1-1.6%). The BE methods overestimated the criterion values by 4-14%, and the single 20-s measurement technique yielded an underestimation of 3.4%. Our results confirm that the HR/V˙O 2 modelling technique, used over a maximal 200-m or 400-m swim, is a valid and accurate procedure for assessing cardiorespiratory and metabolic fitness in competitive swimmers. © Georg Thieme Verlag KG Stuttgart · New York.

  17. Haemoglobin J-Baltimore can be detected by HbA1c electropherogram but with underestimated HbA1c value.

    PubMed

    Brunel, Valéry; Lahary, Agnčs; Chagraoui, Abdeslam; Thuillez, Christian

    2016-01-01

    Glycated haemoglobin (HbA(1c)) is considered the gold standard for assessing diabetes compensation and treatment. In addition, fortuitous detection of haemoglobin variants during HbA1c measurement is not rare. Recently, two publications reported different conclusions on accuracy of HbA(1c) value using capillary electrophoresis method in presence of haemoglobin J-Baltimore (HbJ).
Here we describe the fortuitous detection of unknown HbJ using capillary electrophoresis for measurement of HbA(1c). A patient followed for gestational diabetes in our laboratory presented unknown haemoglobin on Capillarys 2 Flex Piercing analyser which was identified as HbJ. HbJ is not associated with haematological abnormalities. High Performance Liquid Chromatography methods are known to possibly underestimate HbA(1c) value in the presence of this variant. This variant and its glycated form are clearly distinguished on electropherogram but HbJ was responsible for underestimating the true area of HbA(1c).
 Capillary electrophoresis is a good method for detecting HbJ but does not seem suitable for evaluation of HbA(1C) value in patients in presence of HbJ variant.

  18. Local Measurement of the Penetration Depth in the Pnictide Superconductor Ba(Fe_0.95 Co_0.05)_2 As_2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Matsushita, Y.

    2010-01-11

    We use magnetic force microscopy (MFM) to measure the local penetration depth {lambda} in Ba(Fe{sub 0.95}Co{sub 0.05}){sub 2}As{sub 2} single crystals and use scanning SQUID susceptometry to measure its temperature variation down to 0.4 K. We observe that superfluid density {rho}{sub s} over the full temperature range is well described by a clean two-band fully gapped model. We demonstrate that MFM can measure the important and hard-to-determine absolute value of {lambda}, as well as obtain its temperature dependence and spatial homogeneity. We find {rho}{sub s} to be uniform on the submicron scale despite the highly disordered vortex pinning.

  19. 25 CFR 39.807 - How will the Student Unit Value be adjusted annually?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How will the Student Unit Value be adjusted annually? 39.807 Section 39.807 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION THE INDIAN... Program § 39.807 How will the Student Unit Value be adjusted annually? (a) The student unit instructional...

  20. Stratospheric CFCl3, CF2Cl2, and N2O height profile measurements at several latitudes

    NASA Astrophysics Data System (ADS)

    Goldan, P. D.; Kuster, W. C.; Albritton, D. L.; Schmeltekopf, A. L.

    1980-01-01

    The mixing ratios of CFCl3, CF2Cl2, and N2O have been measured as a function of altitude from 6 to 37 km above sea level by using a balloon-borne grab-sampling system. The 24 flights were made during the period July 1976 to March 1979 from Wyoming, Panama, Brazil, and Antarctica. These data are reported here both numerically and graphically, the latter being examined for latitudinal and temporal trends. A mean tropopause height for each location and date was used as the reference for the height profiles. The resulting set of CF2Cl2 and N2O profiles show a discernible dependence on latitude; the lapse rate of these mixing ratios is greater for the mid-latitudes when compared to the equatorial latitudes. The upper tropospheric portion of the CFCl3 and CF2Cl2 data show annual increases of 10.4±3.9 and 10.7±1.9%/yr, respectively, in the northern hemisphere for the middle of the measurement period (end of 1977). Furthermore, the limited number of southern hemispheric data for these constituents are about 8% lower than the northern hemispheric values but have a comparable annual increase. The corresponding N2O data show no interhemispheric differences and the possibility of only a slight increase (less than 2%/yr).

  1. Be 7 solar neutrino measurement with KamLAND

    DOE PAGES

    Gando, A.; Gando, Y.; Hanakago, H.; ...

    2015-11-30

    In this article, we report a measurement of the neutrino-electron elastic scattering rate of 862 keV 7Be solar neutrinos based on a 165.4 kt d exposure of KamLAND. The observed rate is 582 ± 94 (kt d) -1, which corresponds to an 862-keV 7Be solar neutrino flux of (3.26 ± 0.52) × 10 9 cm -2s -1, assuming a pure electron-flavor flux. Comparing this flux with the standard solar model prediction and further assuming three-flavor mixing, a ν e survival probability of 0.66 ± 0.15 is determined from the KamLAND data. Utilizing a global three-flavor oscillation analysis, we obtain amore » total 7Be solar neutrino flux of (5.82 ± 1.02) × 10 9 cm -2s -1, which is consistent with the standard solar model predictions.« less

  2. Establishing traceability of photometric absorbance values for accurate measurements of the haemoglobin concentration in blood

    NASA Astrophysics Data System (ADS)

    Witt, K.; Wolf, H. U.; Heuck, C.; Kammel, M.; Kummrow, A.; Neukammer, J.

    2013-10-01

    Haemoglobin concentration in blood is one of the most frequently measured analytes in laboratory medicine. Reference and routine methods for the determination of the haemoglobin concentration in blood are based on the conversion of haeme, haemoglobin and haemiglobin species into uniform end products. The total haemoglobin concentration in blood is measured using the absorbance of the reaction products. Traceable absorbance measurement values on the highest metrological level are a prerequisite for the calibration and evaluation of procedures with respect to their suitability for routine measurements and their potential as reference measurement procedures. For this purpose, we describe a procedure to establish traceability of spectral absorbance measurements for the haemiglobincyanide (HiCN) method and for the alkaline haematin detergent (AHD) method. The latter is characterized by a higher stability of the reaction product. In addition, the toxic hazard of cyanide, which binds to the iron ion of the haem group and thus inhibits the oxygen transport, is avoided. Traceability is established at different wavelengths by applying total least-squares analysis to derive the conventional quantity values for the absorbance from the measured values. Extrapolation and interpolation are applied to get access to the spectral regions required to characterize the Q-absorption bands of the HiCN and AHD methods, respectively. For absorbance values between 0.3 and 1.8, the contributions of absorbance measurements to the total expanded uncertainties (95% level of confidence) of absorbance measurements range from 1% to 0.4%.

  3. Low 2D:4D values are associated with video game addiction.

    PubMed

    Kornhuber, Johannes; Zenses, Eva-Maria; Lenz, Bernd; Stoessel, Christina; Bouna-Pyrrou, Polyxeni; Rehbein, Florian; Kliem, Sören; Mößle, Thomas

    2013-01-01

    Androgen-dependent signaling regulates the growth of the fingers on the human hand during embryogenesis. A higher androgen load results in lower 2D:4D (second digit to fourth digit) ratio values. Prenatal androgen exposure also impacts brain development. 2D:4D values are usually lower in males and are viewed as a proxy of male brain organization. Here, we quantified video gaming behavior in young males. We found lower mean 2D:4D values in subjects who were classified according to the CSAS-II as having at-risk/addicted behavior (n = 27) compared with individuals with unproblematic video gaming behavior (n = 27). Thus, prenatal androgen exposure and a hyper-male brain organization, as represented by low 2D:4D values, are associated with problematic video gaming behavior. These results may be used to improve the diagnosis, prediction, and prevention of video game addiction.

  4. 47 CFR 2.1057 - Frequency spectrum to be investigated.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Frequency spectrum to be investigated. 2.1057... Frequency spectrum to be investigated. (a) In all of the measurements set forth in §§ 2.1051 and 2.1053, the spectrum shall be investigated from the lowest radio frequency signal generated in the equipment, without...

  5. 47 CFR 2.1057 - Frequency spectrum to be investigated.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Frequency spectrum to be investigated. 2.1057... Frequency spectrum to be investigated. (a) In all of the measurements set forth in §§ 2.1051 and 2.1053, the spectrum shall be investigated from the lowest radio frequency signal generated in the equipment, without...

  6. 47 CFR 2.1057 - Frequency spectrum to be investigated.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Frequency spectrum to be investigated. 2.1057... Frequency spectrum to be investigated. (a) In all of the measurements set forth in §§ 2.1051 and 2.1053, the spectrum shall be investigated from the lowest radio frequency signal generated in the equipment, without...

  7. 47 CFR 2.1057 - Frequency spectrum to be investigated.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Frequency spectrum to be investigated. 2.1057... Frequency spectrum to be investigated. (a) In all of the measurements set forth in §§ 2.1051 and 2.1053, the spectrum shall be investigated from the lowest radio frequency signal generated in the equipment, without...

  8. 47 CFR 2.1057 - Frequency spectrum to be investigated.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Frequency spectrum to be investigated. 2.1057... Frequency spectrum to be investigated. (a) In all of the measurements set forth in §§ 2.1051 and 2.1053, the spectrum shall be investigated from the lowest radio frequency signal generated in the equipment, without...

  9. Protein charge ladders reveal that the net charge of ALS-linked superoxide dismutase can be different in sign and magnitude from predicted values

    PubMed Central

    Shi, Yunhua; Abdolvahabi, Alireza; Shaw, Bryan F

    2014-01-01

    This article utilized “protein charge ladders”—chemical derivatives of proteins with similar structure, but systematically altered net charge—to quantify how missense mutations that cause amyotrophic lateral sclerosis (ALS) affect the net negative charge (Z) of superoxide dismutase-1 (SOD1) as a function of subcellular pH and Zn2+ stoichiometry. Capillary electrophoresis revealed that the net charge of ALS-variant SOD1 can be different in sign and in magnitude—by up to 7.4 units per dimer at lysosomal pH—than values predicted from standard pKa values of amino acids and formal oxidation states of metal ions. At pH 7.4, the G85R, D90A, and G93R substitutions diminished the net negative charge of dimeric SOD1 by up to +2.29 units more than predicted; E100K lowered net charge by less than predicted. The binding of a single Zn2+ to mutant SOD1 lowered its net charge by an additional +2.33 ± 0.01 to +3.18 ± 0.02 units, however, each protein regulated net charge when binding a second, third, or fourth Zn2+ (ΔZ < 0.44 ± 0.07 per additional Zn2+). Both metalated and apo-SOD1 regulated net charge across subcellular pH, without inverting from negative to positive at the theoretical pI. Differential scanning calorimetry, hydrogen-deuterium exchange, and inductively coupled plasma mass spectrometry confirmed that the structure, stability, and metal content of mutant proteins were not significantly affected by lysine acetylation. Measured values of net charge should be used when correlating the biophysical properties of a specific ALS-variant SOD1 protein with its observed aggregation propensity or clinical phenotype. PMID:25052939

  10. Quantum Tasks with Non-maximally Quantum Channels via Positive Operator-Valued Measurement

    NASA Astrophysics Data System (ADS)

    Peng, Jia-Yin; Luo, Ming-Xing; Mo, Zhi-Wen

    2013-01-01

    By using a proper positive operator-valued measure (POVM), we present two new schemes for probabilistic transmission with non-maximally four-particle cluster states. In the first scheme, we demonstrate that two non-maximally four-particle cluster states can be used to realize probabilistically sharing an unknown three-particle GHZ-type state within either distant agent's place. In the second protocol, we demonstrate that a non-maximally four-particle cluster state can be used to teleport an arbitrary unknown multi-particle state in a probabilistic manner with appropriate unitary operations and POVM. Moreover the total success probability of these two schemes are also worked out.

  11. Redetermination of clinobaryl-ite, BaBe(2)Si(2)O(7).

    PubMed

    Domizio, Adrien J Di; Downs, Robert T; Yang, Hexiong

    2012-10-01

    Clinobaryl-ite, ideally BaBe(2)Si(2)O(7) (chemical name barium diberyllium disilicate), is a sorosilicate mineral and dimorphic with baryl-ite. It belongs to a group of compounds characterized by the general formula BaM(2+) (2)Si(2)O(7), with M(2+) = Be, Mg, Fe, Mn, Zn, Co, or Cu, among which the Be-, Fe-, and Cu-members have been found in nature. The crystal structure of clinobaryl-ite has been re-examined in this study based on single-crystal X-ray diffraction data collected from a natural sample from the type locality (Khibiny Massif, Kola Peninsula, Russia). The structure of clinobaryl-ite can be considered as a framework of BeO(4) and SiO(4) tetra-hedra, with one of the O atoms coordinated to two Be and one Si, one coordinated to two Si, and two O atoms coordinated to one Si and one Be atom. The BeO(4) tetra-hedra share corners, forming chains parallel to the c axis, which are inter-linked by the Si(2)O(7) units oriented parallel to the a axis. The Ba(2+) cations (site symmetry m..) are in the framework channels and are coordinated by eleven O atoms in form of an irregular polyhedron. The Si-O(br) (bridging O atom, at site symmetry m..) bond length, the Si-O(nbr) (non-bridging O atoms) bond lengths, and the Si-O-Si angle within the Si(2)O(7) unit are in marked contrast to the corresponding values determined in the previous study [Krivovichev et al. (2004 ▶). N. Jb. Miner. Mh. pp. 373-384].

  12. Assessing soil fluxes using meteoric 10Be: development and application of the Be2D model

    NASA Astrophysics Data System (ADS)

    Campforts, Benjamin; Govers, Gerard; Vanacker, Veerle; Baken, Stijn; Smolders, Erik; Vanderborght, Jan

    2015-04-01

    Meteoric 10Be is a promising and increasingly popular tool to better understand soil fluxes at different timescales. Unlike other, more classical, methods such as the study of sedimentary archives it enables a direct coupling between eroding and deposition sites. However, meteoric 10Be can be mobilized within the soil. Therefore, spatial variations in meteoric 10Be inventories cannot directly be translated into spatial variations in erosion and sedimentation rates: a correct interpretation of measured 10Be inventories requires that both lateral and vertical movement of meteoric 10Be are accounted for. Here, we present a spatially explicit 2D model that allows to simulate the behaviour of meteoric 10Be in the soil system over timescales of up to 1 million year and use the model to investigate the impact of accelerated erosion on meteoric 10Be inventories. The model consists of two parts. A first component deals with advective and diffusive mobility within the soil profile, whereas a second component describes lateral soil (and meteoric 10Be) fluxes over the hillslope. Soil depth is calculated dynamically, accounting for soil production through weathering and lateral soil fluxes. Different types of erosion such as creep, water and tillage erosion are supported. Model runs show that natural soil fluxes can be well reconstructed based on meteoric 10Be inventories, and this for a wide range of geomorphological and pedological conditions. However, extracting signals of human impact and distinguishing them from natural soil fluxes is only feasible when the soil has a rather high retention capacity so that meteoric 10Be is retained in the top soil layer. Application of the Be2D model to an existing data set in the Appalachian Mountains [West et al.,2013] using realistic parameter values for the soil retention capacity as well as for vertical advection resulted in a good agreement between simulated and observed 10Be inventories. This confirms the robustness of the model. We

  13. California safety-net hospitals likely to be penalized by ACA value, readmission, and meaningful-use programs.

    PubMed

    Gilman, Matlin; Adams, E Kathleen; Hockenberry, Jason M; Wilson, Ira B; Milstein, Arnold S; Becker, Edmund R

    2014-08-01

    The Affordable Care Act includes provisions to increase the value obtained from health care spending. A growing concern among health policy experts is that new Medicare policies designed to improve the quality and efficiency of hospital care, such as value-based purchasing (VBP), the Hospital Readmissions Reduction Program (HRRP), and electronic health record (EHR) meaningful-use criteria, will disproportionately affect safety-net hospitals, which are already facing reduced disproportionate-share hospital (DSH) payments under both Medicare and Medicaid. We examined hospitals in California to determine whether safety-net institutions were more likely than others to incur penalties under these programs. To assess quality, we also examined whether mortality outcomes were different at these hospitals. Our study found that compared to non-safety-net hospitals, safety-net institutions had lower thirty-day risk-adjusted mortality rates in the period 2009-11 for acute myocardial infarction, heart failure, and pneumonia and marginally lower adjusted Medicare costs. Nonetheless, safety-net hospitals were more likely than others to be penalized under the VBP program and the HRRP and more likely not to meet EHR meaningful-use criteria. The combined effects of Medicare value-based payment policies on the financial viability of safety-net hospitals need to be considered along with DSH payment cuts as national policy makers further incorporate performance measures into the overall payment system. Project HOPE—The People-to-People Health Foundation, Inc.

  14. What's the Difference? A Model for Measuring the Value Added by Higher Education in Australia

    ERIC Educational Resources Information Center

    Coates, Hamish

    2009-01-01

    Measures of student learning are playing an increasingly significant role in determining the quality and productivity of higher education. This paper evaluates approaches for estimating the value added by university education, and proposes a methodology for use by institutions and systems. The paper argues that value-added measures of learning are…

  15. Online physician ratings fail to predict actual performance on measures of quality, value, and peer review.

    PubMed

    Daskivich, Timothy J; Houman, Justin; Fuller, Garth; Black, Jeanne T; Kim, Hyung L; Spiegel, Brennan

    2018-04-01

    Patients use online consumer ratings to identify high-performing physicians, but it is unclear if ratings are valid measures of clinical performance. We sought to determine whether online ratings of specialist physicians from 5 platforms predict quality of care, value of care, and peer-assessed physician performance. We conducted an observational study of 78 physicians representing 8 medical and surgical specialties. We assessed the association of consumer ratings with specialty-specific performance scores (metrics including adherence to Choosing Wisely measures, 30-day readmissions, length of stay, and adjusted cost of care), primary care physician peer-review scores, and administrator peer-review scores. Across ratings platforms, multivariable models showed no significant association between mean consumer ratings and specialty-specific performance scores (β-coefficient range, -0.04, 0.04), primary care physician scores (β-coefficient range, -0.01, 0.3), and administrator scores (β-coefficient range, -0.2, 0.1). There was no association between ratings and score subdomains addressing quality or value-based care. Among physicians in the lowest quartile of specialty-specific performance scores, only 5%-32% had consumer ratings in the lowest quartile across platforms. Ratings were consistent across platforms; a physician's score on one platform significantly predicted his/her score on another in 5 of 10 comparisons. Online ratings of specialist physicians do not predict objective measures of quality of care or peer assessment of clinical performance. Scores are consistent across platforms, suggesting that they jointly measure a latent construct that is unrelated to performance. Online consumer ratings should not be used in isolation to select physicians, given their poor association with clinical performance.

  16. Towards traceability in CO2 line strength measurements by TDLAS at 2.7 µm

    NASA Astrophysics Data System (ADS)

    Pogány, Andrea; Ott, Oliver; Werhahn, Olav; Ebert, Volker

    2013-11-01

    Direct tunable diode laser absorption spectroscopy (TDLAS) was combined in this study with metrological principles on the determination of uncertainties to measure the line strengths of the P36e and P34e line of 12C16O2 in the ν1+ν3 band at 2.7 μm. Special emphasis was put on traceability and a concise, well-documented uncertainty assessment. We have quantitatively analyzed the uncertainty contributions of different experimental parameters to the uncertainty of the line strength. Establishment of the wavenumber axis and the gas handling procedure proved to be the two major contributors to the final uncertainty. The obtained line strengths at 296 K are 1.593×10-20 cm/molecule for the P36e and 1.981×10-20 cm/molecule for the P34e line, with relative expanded uncertainties of 1.1% and 1.3%, respectively (k=2, corresponding to a 95% confidence level). The measured line strength values are in agreement with literature data (line strengths listed in the HITRAN and GEISA databases), but show an uncertainty, which is at least a factor of 2 lower.

  17. Centeredness Theory: Understanding and Measuring Well-Being Across Core Life Domains

    PubMed Central

    Bloch-Jorgensen, Zephyr T.; Cilione, Patrick J.; Yeung, William W. H.; Gatt, Justine M.

    2018-01-01

    Background: Centeredness Theory (CT) is proposed as a new mental health paradigm that focuses on well-being at a systems-level, across the core life domains of the self, the family unit, relationships, community, and work. The current studies aimed to validate the psychometric properties of a new scale that measures CT against existing well-being and mental health measures. Methods: Study 1 included 488 anonymous online respondents (46% females, 28% males, 25% unknown with median age between 31 and 35 years) across 38 countries who completed the CT scale. Study 2 included 49 first-year psychology students (90% females, mean age of 19 years) from Sydney Australia that completed the CT scale and other well-being and mental health questionnaires at baseline and 2-weeks follow-up. Results: Exploratory and confirmatory factor analyses resulted in a refined 60-item CT scale with five domains, each with four sub-domains. The CT scale demonstrated good internal consistency reliability and test-retest reliability, and showed evidence of convergent validity against other well-being measures (e.g., COMPAS-W Wellbeing Scale, SWLS scale, and Ryff's Psychological Well-being scale). Conclusions: The CT scale appears to be a reliable measure of well-being at a systems-level. Future studies need to confirm these findings in larger heterogeneous samples. PMID:29765344

  18. Applying the Expectancy-Value Model to understand health values.

    PubMed

    Zhang, Xu-Hao; Xie, Feng; Wee, Hwee-Lin; Thumboo, Julian; Li, Shu-Chuen

    2008-03-01

    Expectancy-Value Model (EVM) is the most structured model in psychology to predict attitudes by measuring attitudinal attributes (AAs) and relevant external variables. Because health value could be categorized as attitude, we aimed to apply EVM to explore its usefulness in explaining variances in health values and investigate underlying factors. Focus group discussion was carried out to identify the most common and significant AAs toward 5 different health states (coded as 11111, 11121, 21221, 32323, and 33333 in EuroQol Five-Dimension (EQ-5D) descriptive system). AAs were measured in a sum of multiplications of subjective probability (expectancy) and perceived value of attributes with 7-point Likert scales. Health values were measured using visual analog scales (VAS, range 0-1). External variables (age, sex, ethnicity, education, housing, marital status, and concurrent chronic diseases) were also incorporated into survey questionnaire distributed by convenience sampling among eligible respondents. Univariate analyses were used to identify external variables causing significant differences in VAS. Multiple linear regression model (MLR) and hierarchical regression model were used to investigate the explanatory power of AAs and possible significant external variable(s) separately or in combination, for each individual health state and a mixed scenario of five states, respectively. Four AAs were identified, namely, "worsening your quality of life in terms of health" (WQoL), "adding a burden to your family" (BTF), "making you less independent" (MLI) and "unable to work or study" (UWS). Data were analyzed based on 232 respondents (mean [SD] age: 27.7 [15.07] years, 49.1% female). Health values varied significantly across 5 health states, ranging from 0.12 (33333) to 0.97 (11111). With no significant external variables identified, EVM explained up to 62% of the variances in health values across 5 health states. The explanatory power of 4 AAs were found to be between 13

  19. Is Log Ratio a Good Value for Measuring Return in Stock Investments?

    NASA Astrophysics Data System (ADS)

    Ultsch, Alfred

    Measuring the rate of return is an important issue for theory and practice of investments in the stock market. A common measure for rate of return is the logarithm of the ratio of successive prices (LogRatio). In this paper it is shown that LogRatio as well as arithmetic return rate (Ratio) have several disadvantages. As an alternative relative differences (RelDiff) are proposed to measure return. The stability against numerical and rounding errors of RelDiff is much better than for LogRatios and Ratio). RelDiff values are identical to LogRatios and Return for small absolutes. The usage of RelDiff maps returns to a finite range. For most subsequent analyses this is a big advantage. The usefulness of the approach is demonstrated on daily return rates of a large set of actual stocks. It is shown that returns can be modeled with a very simple mixture of distributions in great precision using Relative differences.

  20. It's hard to be green: Reverse green value chain.

    PubMed

    Couto, João; Tiago, Teresa; Gil, Artur; Tiago, Flávio; Faria, Sandra

    2016-08-01

    Firms have recently discovered that it is not enough to optimize internal processes and relationships with partners along the value chain to create a sustainable competitive market position. A clear customer orientation, which acknowledges that consumer buying behavior is complex and includes many elements implied in the value chain, is required. As companies offering green products are no exception to this rule, this study analyzes consumer behavior in Europe from a reserve green supply chain management perspective, using descriptive analyses and a structural equation model, with data collected by Flash Barometer comprising 26,573 responses from 28 European countries. The results suggest that European consumers are conscious of the green concept, but are not willing to buy or pay more for these products since the value is unclear. Companies offering green products must therefore rethink their strategies, especially in terms of value proposition, communication strategies, and eco-labeling. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Evaluation of the ion-density measurements by the Indian satellite SROSS-C2

    NASA Astrophysics Data System (ADS)

    Subrahmanyam, P.; Jain, A. R.; Maini, H. K.; Bahl, M.; Das, Rupesh M.; Garg, S. C.; Niranjan, K.

    2010-12-01

    The ion and electron F region plasma measurements made by the ion and electron Retarding Potential Analyzers (RPAs) onboard the Indian satellite SROSS-C2, have yielded excellent data set over the Indian region for more than half a solar cycle, after the SROSS-C2 launch in May 1994. The absolute ion density, ion temperature, and ion composition parameters are derived from these in situ measurements and used by many workers. In this paper the absolute values of ion density derived from the ion RPA measurements are compared and evaluated with the measurements made by ground-based ionosondes located in the Indian region and close to the SROSS-C2 orbital path. It is shown that a slight adjustment in efficiency factor of the ion RPA sensor brings the in situ measurements much closer to those obtained from the ground-based ionosonde measurements taking into account the model calculations. It may be mentioned that this is a correction to the ion density measurement by SROSS-C2 by a fixed proportion (14-11.4%). The effect of change in efficiency factor on the ion current, which is used to deduce the ion number density, is demonstrated and discussed.

  2. A precision measurement of the neutron 2. Probing the color force

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Posik, Matthew R.

    2014-01-01

    The g 2 nucleon spin-dependent structure function measured in electron deep inelastic scattering contains information beyond the simple parton model description of the nucleon. It provides insight into quark-gluon correlations and a path to access the confining local color force a struck quark experiences just as it is hit by the virtual photon due to the remnant di-quark. The quantity d 2, a measure of this local color force, has its information encoded in an x 2 weighted integral of a linear combination of spin structure functions g 1 and g 2 and thus is dominated by the valence-quark regionmore » at large momentum fraction x. To date, theoretical calculations and experimental measurements of the neutron d 2 differ by about two standard deviations. Therefore, JLab experiment E06-014, performed in Hall A, made a precision measurement of this quantity at two mean four momentum transfers values of 3.21 and 4.32 GeV 2. Double spin asymmetries and absolute cross-sections were measured in both DIS and resonance regions by scattering longitudinally polarized electrons at beam energies of 4.74 and 5.89 GeV from a longitudinally and transversely polarized 3He target. Results for the absolute cross-sections and spin structure functions on 3He will be presented in the dissertation, as well as results for the neutron d 2 and extracted color forces.« less

  3. Postselected weak measurement beyond the weak value

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Geszti, Tamas

    2010-04-15

    Closed expressions are derived for the quantum measurement statistics of pre- and postselected Gaussian particle beams. The weakness of the preselection step is shown to compete with the nonorthogonality of postselection in a transparent way. The approach is shown to be useful in analyzing postselection-based signal amplification, allowing measurements to be extended far beyond the range of validity of the well-known Aharonov-Albert-Vaidman limit. Additionally, the present treatment connects postselected weak measurement to the topic of phase-contrast microscopy.

  4. Value-Added Measures of Education Performance: Clearing Away the Smoke and Mirrors. Policy Brief 10-4

    ERIC Educational Resources Information Center

    Harris, Douglas N.

    2010-01-01

    In this policy brief, the author explores the problems with attainment measures when it comes to evaluating performance at the school level, and explores the best uses of value-added measures. These value-added measures, the author writes, are useful for sorting out-of-school influences from school influences or from teacher performance, giving…

  5. Measuring daily Value-at-Risk of SSEC index: A new approach based on multifractal analysis and extreme value theory

    NASA Astrophysics Data System (ADS)

    Wei, Yu; Chen, Wang; Lin, Yu

    2013-05-01

    Recent studies in the econophysics literature reveal that price variability has fractal and multifractal characteristics not only in developed financial markets, but also in emerging markets. Taking high-frequency intraday quotes of the Shanghai Stock Exchange Component (SSEC) Index as example, this paper proposes a new method to measure daily Value-at-Risk (VaR) by combining the newly introduced multifractal volatility (MFV) model and the extreme value theory (EVT) method. Two VaR backtesting techniques are then employed to compare the performance of the model with that of a group of linear and nonlinear generalized autoregressive conditional heteroskedasticity (GARCH) models. The empirical results show the multifractal nature of price volatility in Chinese stock market. VaR measures based on the multifractal volatility model and EVT method outperform many GARCH-type models at high-risk levels.

  6. Low 2D:4D Values Are Associated with Video Game Addiction

    PubMed Central

    Kornhuber, Johannes; Zenses, Eva-Maria; Lenz, Bernd; Stoessel, Christina; Bouna-Pyrrou, Polyxeni; Rehbein, Florian; Kliem, Sören; Mößle, Thomas

    2013-01-01

    Androgen-dependent signaling regulates the growth of the fingers on the human hand during embryogenesis. A higher androgen load results in lower 2D:4D (second digit to fourth digit) ratio values. Prenatal androgen exposure also impacts brain development. 2D:4D values are usually lower in males and are viewed as a proxy of male brain organization. Here, we quantified video gaming behavior in young males. We found lower mean 2D:4D values in subjects who were classified according to the CSAS-II as having at-risk/addicted behavior (n = 27) compared with individuals with unproblematic video gaming behavior (n = 27). Thus, prenatal androgen exposure and a hyper-male brain organization, as represented by low 2D:4D values, are associated with problematic video gaming behavior. These results may be used to improve the diagnosis, prediction, and prevention of video game addiction. PMID:24236143

  7. Perceptions of Successful Aging: Intergenerational Voices Value Well-Being.

    PubMed

    Kelly, Gina Aalgaard; Lazarus, Jennie

    2015-03-01

    This study explored the perceptions of successful aging from intergenerational perspectives. A total of 66 participants were interviewed from three different generations including college students, parents, and grandparents. After qualitative data collection and analyses were used, five conceptual categories emerged from the data that related to perceptions of successful aging. The five concepts include wisdom, health, financial stability, staying active, and well-being. Conceptual categories emerged from the participants of different generations, and some were interconnected across generations. Each category is representative of major thematic patterns. Well-being was the primary concept which emerged because all three generations perceived and explicitly discussed well-being as the most valued aspect of successful aging. Previous successful aging research informed the use of a bio-psycho-social theoretical lens to frame the study findings and discussion. © The Author(s) 2015.

  8. Optimal clinical time for reliable measurement of transcutaneous CO2 with ear probes: counterbalancing overshoot and the vasodilatation effect.

    PubMed

    Domingo, Christian; Canturri, Elisa; Moreno, Amalia; Espuelas, Humildad; Vigil, Laura; Luján, Manel

    2010-01-01

    To determine the optimal clinical reading time for the transcutaneous measurement of oxygen saturation (SpO(2)) and transcutaneous CO(2) (TcPCO(2)) in awake spontaneously breathing individuals, considering the overshoot phenomenon (transient overestimation of arterial PaCO(2)). EXPERIMENTAL SECTION: Observational study of 91 (75 men) individuals undergoing forced spirometry, measurement of SpO(2) and TcPCO(2) with the SenTec monitor every two minutes until minute 20 and arterial blood gas (ABG) analysis. Overshoot severity: (a) mild (0.1-1.9 mm Hg); (b) moderate (2-4.9 mm Hg); (c) severe: (>5 mm Hg). The mean difference was calculated for SpO(2) and TcPCO(2) and arterial values of PaCO(2) and SpO(2). The intraclass correlation coefficient (ICC) between monitor readings and blood values was calculated as a measure of agreement. The mean age was 63.1 ± 11.8 years. Spirometric values: FVC: 75.4 ± 6.2%; FEV(1): 72.9 ± 23.9%; FEV(1)/FVC: 70 ± 15.5%. ABG: PaO(2): 82.6 ± 13.2; PaCO(2): 39.9.1 ± 4.8 mmHg; SaO(2): 95.3 ± 4.4%. Overshoot analysis: overshoot was mild in 33 (36.3%) patients, moderate in 20 (22%) and severe in nine (10%); no overshoot was observed in 29 (31%) patients. The lowest mean differences between arterial blood gas and TcPCO(2) was -0.57 mmHg at minute 10, although the highest ICC was obtained at minutes 12 and 14 (>0.8). The overshoot lost its influence after minute 12. For SpO(2), measurements were reliable at minute 2. The optimal clinical reading measurement recommended for the ear lobe TcPCO(2) measurement ranges between minute 12 and 14. The SpO(2) measurement can be performed at minute 2.

  9. Be 7 solar neutrino measurement with KamLAND

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gando, A.; Gando, Y.; Hanakago, H.

    2015-11-30

    We report a measurement of the neutrino-electron elastic scattering rate of 862 keV 7Be solar neutrinos based on a 165.4 kt d exposure of KamLAND. The observed rate is 582±94(kt d) ₋1, which corresponds to an 862-keV 7Be solar neutrino flux of (3.26±0.52)×10 9cm ₋2s ₋1, assuming a pure electron-flavor flux. Comparing this flux with the standard solar model prediction and further assuming three-flavor mixing, a ν e survival probability of 0.66±0.15 is determined from the KamLAND data. Lastly, utilizing a global three-flavor oscillation analysis, we obtain a total 7Be solar neutrino flux of (5.82±1.02)×10 9cm ₋2s ₋1, which ismore » consistent with the standard solar model predictions.« less

  10. Comparison of the T2-star Values of Placentas Obtained from Pre-eclamptic Patients with Those of a Control Group: an Ex-vivo Magnetic Resonance Imaging Study.

    PubMed

    Yurttutan, Nursel; Bakacak, Murat; Kızıldağ, Betül

    2017-09-29

    Endotel dysfunction, vasoconstriction, and oxidative stress are described in the pathophysiology of pre-eclampsia, but its aetiology has not been revealed clearly. To examine whether there is a difference between the placentas of pre-eclamptic pregnant women and those of a control group in terms of their T2 star values. Case-control study. Twenty patients diagnosed with pre-eclampsia and 22 healthy controls were included in this study. The placentas obtained after births performed via Caesarean section were taken into the magnetic resonance imaging area in plastic bags within the first postnatal hour, and imaging was performed via modified DIXON-Quant sequence. Average values were obtained by performing T2 star measurements from four localisations on the placentas. T2 star values measured in the placentas of the control group were found to be significantly lower than those in the pre-eclampsia group (p<0.01). While the mean T2 star value in the pre-eclamptic group was found to be 37.48 ms (standard deviation ± 11.3), this value was 28.74 (standard deviation ± 8.08) in the control group. The cut-off value for the T2 star value, maximising the accuracy of diagnosis, was 28.59 ms (area under curve: 0.741; 95% confidence interval: 0.592-0.890); sensitivity and specificity were 70% and 63.6%, respectively. This study, the T2 star value, which is an indicator of iron amount, was found to be significantly lower in the control group than in the pre-eclampsia group. This may be related to the reduction in blood flow to the placenta due to endothelial dysfunction and vasoconstriction, which are important in pre-eclampsia pathophysiology.

  11. T2 values of articular cartilage in clinically relevant subregions of the asymptomatic knee.

    PubMed

    Surowiec, Rachel K; Lucas, Erin P; Fitzcharles, Eric K; Petre, Benjamin M; Dornan, Grant J; Giphart, J Erik; LaPrade, Robert F; Ho, Charles P

    2014-06-01

    In order for T2 mapping to become more clinically applicable, reproducible subregions and standardized T2 parameters must be defined. This study sought to: (1) define clinically relevant subregions of knee cartilage using bone landmarks identifiable on both MR images and during arthroscopy and (2) determine healthy T2 values and T2 texture parameters within these subregions. Twenty-five asymptomatic volunteers (age 18-35) were evaluated with a sagittal T2 mapping sequence. Manual segmentation was performed by three raters, and cartilage was divided into twenty-one subregions modified from the International Cartilage Repair Society Articular Cartilage Mapping System. Mean T2 values and texture parameters (entropy, variance, contrast, homogeneity) were recorded for each subregion, and inter-rater and intra-rater reliability was assessed. The central regions of the condyles had significantly higher T2 values than the posterior regions (P < 0.05) and higher variance than the posterior region on the medial side (P < 0.001). The central trochlea had significantly greater T2 values than the anterior and posterior condyles. The central lateral plateau had lower T2 values, lower variance, higher homogeneity, and lower contrast than nearly all subregions in the tibia. The central patellar regions had higher entropy than the superior and inferior regions (each P ≤ 0.001). Repeatability was good to excellent for all subregions. Significant differences in mean T2 values and texture parameters were found between subregions in this carefully selected asymptomatic population, which suggest that there is normal variation of T2 values within the knee joint. The clinically relevant subregions were found to be robust as demonstrated by the overall high repeatability.

  12. Translating HbA1c measurements into estimated average glucose values in pregnant women with diabetes.

    PubMed

    Law, Graham R; Gilthorpe, Mark S; Secher, Anna L; Temple, Rosemary; Bilous, Rudolf; Mathiesen, Elisabeth R; Murphy, Helen R; Scott, Eleanor M

    2017-04-01

    This study aimed to examine the relationship between average glucose levels, assessed by continuous glucose monitoring (CGM), and HbA 1c levels in pregnant women with diabetes to determine whether calculations of standard estimated average glucose (eAG) levels from HbA 1c measurements are applicable to pregnant women with diabetes. CGM data from 117 pregnant women (89 women with type 1 diabetes; 28 women with type 2 diabetes) were analysed. Average glucose levels were calculated from 5-7 day CGM profiles (mean 1275 glucose values per profile) and paired with a corresponding (±1 week) HbA 1c measure. In total, 688 average glucose-HbA 1c pairs were obtained across pregnancy (mean six pairs per participant). Average glucose level was used as the dependent variable in a regression model. Covariates were gestational week, study centre and HbA 1c . There was a strong association between HbA 1c and average glucose values in pregnancy (coefficient 0.67 [95% CI 0.57, 0.78]), i.e. a 1% (11 mmol/mol) difference in HbA 1c corresponded to a 0.67 mmol/l difference in average glucose. The random effects model that included gestational week as a curvilinear (quadratic) covariate fitted best, allowing calculation of a pregnancy-specific eAG (PeAG). This showed that an HbA 1c of 8.0% (64 mmol/mol) gave a PeAG of 7.4-7.7 mmol/l (depending on gestational week), compared with a standard eAG of 10.2 mmol/l. The PeAG associated with maintaining an HbA 1c level of 6.0% (42 mmol/mol) during pregnancy was between 6.4 and 6.7 mmol/l, depending on gestational week. The HbA 1c -average glucose relationship is altered by pregnancy. Routinely generated standard eAG values do not account for this difference between pregnant and non-pregnant individuals and, thus, should not be used during pregnancy. Instead, the PeAG values deduced in the current study are recommended for antenatal clinical care.

  13. The Prevalence of Nocturia and Nocturnal Polyuria: Can New Cutoff Values Be Suggested According to Age and Sex?

    PubMed Central

    2016-01-01

    Purpose The aims of this study were to assess the prevalence of nocturia and nocturnal polyuria (NP) and to define new cutoff values according to age and sex for both conditions. Methods Data from a population-based prevalence survey conducted among a random sample of 2,128 adults were analyzed in this study. Participants were requested to fill out a questionnaire including the International Continence Society (ICS) definitions of lower urinary tract symptoms and the International Consultation on Incontinence Questionnaire - Short Form. Additionally, a 1-day bladder diary was given to each individual. The participants were divided into 5 age groups. The prevalence of nocturia was calculated based on definitions of nocturia as ≥1 voiding episodes, ≥2 episodes, and ≥3 episodes. NP was evaluated according to the ICS definition. The mean±standard errors and 95th percentile values were calculated in each group as new cutoff values for NP. Results The prevalence of nocturia was estimated as 28.4%, 17.6%, and 8.9% for ≥1, ≥2, and ≥3 voiding episodes each night, respectively. When nocturia was defined as 2 or more voiding episodes at night, the prevalence decreased significantly. The mean NP index was 29.4%±15.0% in men and 23.1%±11.8% in women. For the age groups of <50 years, 50–59 years, and ≥60 years, the new cutoff values for the diagnosis of NP were calculated as 48%, 69%, and 59% for men and 41%, 50%, and 42% for women, respectively. Conclusions We found that the definition of nocturia was still controversial and that waking up once for voiding might be within the normal spectrum of behavior. The definition of NP should be modified, and new cutoff values should be defined using the data presented in our study and in other forthcoming studies. PMID:28043108

  14. Assessment of interchangeability rate between 2 methods of measurements: An example with a cardiac output comparison study.

    PubMed

    Lorne, Emmanuel; Diouf, Momar; de Wilde, Robert B P; Fischer, Marc-Olivier

    2018-02-01

    The Bland-Altman (BA) and percentage error (PE) methods have been previously described to assess the agreement between 2 methods of medical or laboratory measurements. This type of approach raises several problems: the BA methodology constitutes a subjective approach to interchangeability, whereas the PE approach does not take into account the distribution of values over a range. We describe a new methodology that defines an interchangeability rate between 2 methods of measurement and cutoff values that determine the range of interchangeable values. We used a simulated data and a previously published data set to demonstrate the concept of the method. The interchangeability rate of 5 different cardiac output (CO) pulse contour techniques (Wesseling method, LiDCO, PiCCO, Hemac method, and Modelflow) was calculated, in comparison with the reference pulmonary artery thermodilution CO using our new method. In our example, Modelflow with a good interchangeability rate of 93% and a cutoff value of 4.8 L min, was found to be interchangeable with the thermodilution method for >95% of measurements. Modelflow had a higher interchangeability rate compared to Hemac (93% vs 86%; P = .022) or other monitors (Wesseling cZ = 76%, LiDCO = 73%, and PiCCO = 62%; P < .0001). Simulated data and reanalysis of a data set comparing 5 CO monitors against thermodilution CO showed that, depending on the repeatability of the reference method, the interchangeability rate combined with a cutoff value could be used to define the range of values over which interchangeability remains acceptable.

  15. We do not know what we do not know: innovative approaches to value measurement.

    PubMed

    Laviana, Aaron A; Resnick, Matthew J

    2018-07-01

    Over the past several years, there has been an increasing focus on improving the 'value' of healthcare delivered, defined as the ratio of clinical outcomes to the costs incurred to achieve them. The former U.S. Secretary of Health and Human Services Sylvia Burwell announced in 2015 that the majority of healthcare payments in the Medicare and Medicaid programmes will align with value by 2018. Although this has yet to fully mature, numerous health systems have restructured with a goal of improving the value of care delivered to their populations. Nevertheless, there remain important unanswered questions regarding how we measure value in the current U.S. healthcare system. The purpose of this review is to highlight innovations that are not only making it easier to measure value but also to improve care from the patient, provider and healthcare system perspectives. Behavioural start-ups and the introduction of relatively inexpensive health coaches are starting to permeate the healthcare landscape. These coaches are the consumers' advocate, acting as the quarterback of an extended care team in order to optimize health. Furthermore, time-driven activity-based costing has allowed us to understand costs on a more granular level, and novel tracking software may further automate these costing algorithms in order to better facilitate their dissemination. We must all work to enable new models of care that improve value by incentivizing individuals, payers and providers to improve health, rather than treat the disease after it manifests. We must also continue to improve the efficiency of healthcare delivery largely through improvements in value measurement.

  16. Measuring NO, NO2, CO2 and O3 with low-cost sensors

    NASA Astrophysics Data System (ADS)

    Müller, Michael; Graf, Peter; Hüglin, Christoph

    2017-04-01

    Inexpensive sensors measuring ambient gas concentrations can be integrated in sensor units forming dense sensor networks. The utilized sensors have to be sufficiently accurate as the value of such networks directly depends on the information they provide. Thus, thorough testing of sensors before bringing them into service and the application of effective strategies for performance monitoring and adjustments during service are key elements for operating the low-cost sensors that are currently available on the market. We integrated several types of low-cost sensors into sensor units (Alphasense NO2 B4/B42F/B43F, Alphasense NO B4, SensAir CO2 LP8, Aeroqual O3 SM50), run them in the field next to instruments of air quality monitoring stations and performed tests in the laboratory. The poster summarizes our findings regarding the achieved sensor accuracy, methods to improve sensor performance as well as strategies to monitor the current state of the sensor (drifts, sensitivity) within a sensor network.

  17. Quasi-probabilities in conditioned quantum measurement and a geometric/statistical interpretation of Aharonov's weak value

    NASA Astrophysics Data System (ADS)

    Lee, Jaeha; Tsutsui, Izumi

    2017-05-01

    We show that the joint behavior of an arbitrary pair of (generally noncommuting) quantum observables can be described by quasi-probabilities, which are an extended version of the standard probabilities used for describing the outcome of measurement for a single observable. The physical situations that require these quasi-probabilities arise when one considers quantum measurement of an observable conditioned by some other variable, with the notable example being the weak measurement employed to obtain Aharonov's weak value. Specifically, we present a general prescription for the construction of quasi-joint probability (QJP) distributions associated with a given combination of observables. These QJP distributions are introduced in two complementary approaches: one from a bottom-up, strictly operational construction realized by examining the mathematical framework of the conditioned measurement scheme, and the other from a top-down viewpoint realized by applying the results of the spectral theorem for normal operators and their Fourier transforms. It is then revealed that, for a pair of simultaneously measurable observables, the QJP distribution reduces to the unique standard joint probability distribution of the pair, whereas for a noncommuting pair there exists an inherent indefiniteness in the choice of such QJP distributions, admitting a multitude of candidates that may equally be used for describing the joint behavior of the pair. In the course of our argument, we find that the QJP distributions furnish the space of operators in the underlying Hilbert space with their characteristic geometric structures such that the orthogonal projections and inner products of observables can be given statistical interpretations as, respectively, “conditionings” and “correlations”. The weak value Aw for an observable A is then given a geometric/statistical interpretation as either the orthogonal projection of A onto the subspace generated by another observable B, or

  18. Reference Values of Grip Strength, Prevalence of Low Grip Strength, and Factors Affecting Grip Strength Values in Chinese Adults.

    PubMed

    Yu, Ruby; Ong, Sherlin; Cheung, Osbert; Leung, Jason; Woo, Jean

    2017-06-01

    The objectives of this study were to update the reference values of grip strength, to estimate the prevalence of low grip strength, and to examine the impact of different aspects of measurement protocol on grip strength values in Chinese adults. A cross-sectional survey of Chinese men (n = 714) and women (n = 4014) aged 18-102 years was undertaken in different community settings in Hong Kong. Grip strength was measured with a digital dynamometer (TKK 5401 Grip-D; Takei, Niigata, Japan). Low grip strength was defined as grip strength 2 standard deviations or more below the mean for young adults. The effects of measurement protocol on grip strength values were examined in a subsample of 45 men and women with repeated measures of grip strength taken with a hydraulic dynamometer (Baseline; Fabrication Enterprises Inc, Irvington, NY), using pair t-tests, intraclass correlation coefficient, and Bland and Altman plots. Grip strength was greater among men than among women (P < .001) and the rate of decline differed between sexes (P < .001). The prevalence of low grip strength also increased with age, reaching a rate of 16.5% in men and 20.6% in women aged 65+. Although the TKK digital dynamometer gave higher grip strength values than the Baseline hydraulic dynamometer (P < .001), the degree of agreement between the 2 dynamometers was satisfactory. Higher grip strength values were also observed when the measurement was performed with the elbow extended in a standing position, compared with that with the elbow flexed at 90° in a sitting position, using the same dynamometer (P < .05). This study updated the reference values of grip strength and estimated the prevalence of low grip strength among Chinese adults spanning a wide age range. These findings might be useful for risk estimation and evaluation of interventions. However, grip strength measurements should be interpreted with caution, as grip strength values can be affected by type of dynamometer used

  19. 31 CFR 406.2 - Custody of seized gold valued not in excess of $2,500.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Finance (Continued) SECRET SERVICE, DEPARTMENT OF THE TREASURY SEIZURE AND FORFEITURE OF GOLD FOR... excess of $2,500. Any gold, the value of which does not exceed $2,500, seized by officers of the Secret... for further investigation by the Secret Service, shall be placed forthwith by the seizing officer in...

  20. 31 CFR 406.2 - Custody of seized gold valued not in excess of $2,500.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Finance (Continued) SECRET SERVICE, DEPARTMENT OF THE TREASURY SEIZURE AND FORFEITURE OF GOLD FOR... excess of $2,500. Any gold, the value of which does not exceed $2,500, seized by officers of the Secret... for further investigation by the Secret Service, shall be placed forthwith by the seizing officer in...

  1. 31 CFR 406.2 - Custody of seized gold valued not in excess of $2,500.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Finance (Continued) SECRET SERVICE, DEPARTMENT OF THE TREASURY SEIZURE AND FORFEITURE OF GOLD FOR... excess of $2,500. Any gold, the value of which does not exceed $2,500, seized by officers of the Secret... for further investigation by the Secret Service, shall be placed forthwith by the seizing officer in...

  2. 31 CFR 406.2 - Custody of seized gold valued not in excess of $2,500.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Finance (Continued) SECRET SERVICE, DEPARTMENT OF THE TREASURY SEIZURE AND FORFEITURE OF GOLD FOR... excess of $2,500. Any gold, the value of which does not exceed $2,500, seized by officers of the Secret... for further investigation by the Secret Service, shall be placed forthwith by the seizing officer in...

  3. 31 CFR 406.2 - Custody of seized gold valued not in excess of $2,500.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Finance (Continued) SECRET SERVICE, DEPARTMENT OF THE TREASURY SEIZURE AND FORFEITURE OF GOLD FOR... excess of $2,500. Any gold, the value of which does not exceed $2,500, seized by officers of the Secret... for further investigation by the Secret Service, shall be placed forthwith by the seizing officer in...

  4. MFL Benchmark Problem 2: Laboratory Measurements

    NASA Astrophysics Data System (ADS)

    Etcheverry, J.; Pignotti, A.; Sánchez, G.; Stickar, P.

    2003-03-01

    This experiment involves the measurement of the magnetic flux leaked from a rotating seamless steel tube with two machined notches. The signal measured is the radial component of the leaked field at a fixed point in space, as a function of the notch position, for four values of the liftoff and two notches. As the pipe tangential velocity was varied between 0.23 and 0.62 m/s, the sole observed effect was that of increasing the signal by a value that grows linearly with the velocity and is independent of the notch angular position.

  5. Added value measures in education show genetic as well as environmental influence.

    PubMed

    Haworth, Claire M A; Asbury, Kathryn; Dale, Philip S; Plomin, Robert

    2011-02-02

    Does achievement independent of ability or previous attainment provide a purer measure of the added value of school? In a study of 4000 pairs of 12-year-old twins in the UK, we measured achievement with year-long teacher assessments as well as tests. Raw achievement shows moderate heritability (about 50%) and modest shared environmental influences (25%). Unexpectedly, we show that for indices of the added value of school, genetic influences remain moderate (around 50%), and the shared (school) environment is less important (about 12%). The pervasiveness of genetic influence in how and how much children learn is compatible with an active view of learning in which children create their own educational experiences in part on the basis of their genetic propensities.

  6. Seeking Optimal Region-Of-Interest (ROI) Single-Value Summary Measures for fMRI Studies in Imaging Genetics

    PubMed Central

    Tong, Yunxia; Chen, Qiang; Nichols, Thomas E.; Rasetti, Roberta; Callicott, Joseph H.; Berman, Karen F.; Weinberger, Daniel R.; Mattay, Venkata S.

    2016-01-01

    A data-driven hypothesis-free genome-wide association (GWA) approach in imaging genetics studies allows screening the entire genome to discover novel genes that modulate brain structure, chemistry, and function. However, a whole brain voxel-wise analysis approach in such genome-wide based imaging genetic studies can be computationally intense and also likely has low statistical power since a stringent multiple comparisons correction is needed for searching over the entire genome and brain. In imaging genetics with functional magnetic resonance imaging (fMRI) phenotypes, since many experimental paradigms activate focal regions that can be pre-specified based on a priori knowledge, reducing the voxel-wise search to single-value summary measures within a priori ROIs could prove efficient and promising. The goal of this investigation is to evaluate the sensitivity and reliability of different single-value ROI summary measures and provide guidance in future work. Four different fMRI databases were tested and comparisons across different groups (patients with schizophrenia, their siblings, vs. normal control subjects; across genotype groups) were conducted. Our results show that four of these measures, particularly those that represent values from the top most-activated voxels within an ROI are more powerful at reliably detecting group differences and generating greater effect sizes than the others. PMID:26974435

  7. Applying the silver-tube introduction method for thermal conversion elemental analyses and a new δ2H value for NBS 22 oil

    USGS Publications Warehouse

    Coplen, Tyler B.; Qi, Haiping

    2010-01-01

    The δ2HVSMOW–SLAP value of total hydrogen of the international measurement standard NBS 22 oil was determined by a new method of sealing water in silver tubes for use in a thermal conversion elemental analysis (TC/EA) reduction unit. The isotopic fractionation of water due to evaporation is virtually non-existent in this silver-tube method. A new value for the δ2HVSMOW–SLAP of NBS 22 oil, calibrated with isotopic reference waters, was determined to be −116.9 ± 0.8‰ (1σ and n = 31).

  8. Atmospheric H2O2 measurement: comparison of cold trap method with impinger bubbling method

    NASA Technical Reports Server (NTRS)

    Sakugawa, H.; Kaplan, I. R.

    1987-01-01

    Collection of atmospheric H2O2 was performed by a cold trap method using dry ice-acetone as the refrigerant. The air was drawn by a pump into a glass gas trap immersed in the dry ice-acetone slush in a dewar flask at a flow rate of 2.5 l min-1 for approximately 2 h. Collection efficiency was > 99% and negligible interferences by O3, SO2 or organic matter with the collected H2O2 in the trap were observed. This method was compared with the air impinger bubbling method which has been previously described (Kok et al., 1978a, b, Envir. Sci. Technol. 12, 1072-1080). The measured total peroxide (H2O2 + organic peroxide) values in a series of aim samples collected by the impinger bubbling method (0.06-3.7 ppb) were always higher than those obtained by the cold trap method (0.02-1.2 ppb). Laboratory experiments suggest that the difference in values between the two methods probably results from the aqueous phase generation of H2O2 and organic peroxide in the impinger solution by a reaction of atmospheric O3 with olefinic and aromatic compounds. If these O3-organic compound reactions which occur in the impinger also occur in aqueous droplets in the atmosphere, the process could be very important for aqueous phase generation of H2O2 in clouds and rainwater.

  9. Blood glucose measurement in patients with suspected diabetic ketoacidosis: a comparison of Abbott MediSense PCx point-of-care meter values to reference laboratory values.

    PubMed

    Blank, Fidela S J; Miller, Moses; Nichols, James; Smithline, Howard; Crabb, Gillian; Pekow, Penelope

    2009-04-01

    The purpose of this study is to compare blood glucose levels measured by a point of care (POC) device to laboratory measurement using the same sample venous blood from patients with suspected diabetic ketoacidosis (DKA). A descriptive correlational design was used for this IRB-approved quality assurance project. The study site was the 50-bed BMC emergency department (ED) which has an annual census of over 100,000 patient visits. The convenience sample consisted of 54 blood samples from suspected DKA patients with orders for hourly blood draws for glucose measurement. Spearman correlations of the glucose POC values, reference lab values, and differences between the two, were evaluated. A chi-square test was used to evaluate the association between the acidosis status and FDA acceptability of POC values. Patient age range was 10-86 years; 63% were females; 46% had a final diagnosis of DKA. POC values underestimated glucose levels 93% of the time. There was a high correlation between the lab value and the magnitude of the difference, (lab minus POC value) indicating that the higher the true glucose value, the greater the difference between the lab and the POC value. A chi-square test showed no overall association between acidosis and FDA-acceptability. The POC values underestimated lab reported glucose levels in 50 of 54 cases even with the use of same venous sample sent to the lab, which make it highly unreliable for use in monitoring suspected DKA patients.

  10. Improving health care, Part 1: The clinical value compass.

    PubMed

    Nelson, E C; Mohr, J J; Batalden, P B; Plume, S K

    1996-04-01

    CLINICAL VALUE COMPASS APPROACH: The clinical Value Compass, named to reflect its similarity in layout to a directional compass, has at its four cardinal points (1) functional status, risk status, and well-being; (2) costs; (3) satisfaction with health care and perceived benefit; and (4) clinical outcomes. To manage and improve the value of health care services, providers will need to measure the value of care for similar patient populations, analyze the internal delivery processes, run tests of changed delivery processes, and determine if these changes lead to better outcomes and lower costs. GETTING STARTED--OUTCOMES AND AIM: In the case example, the team's aim is "to find ways to continually improve the quality and value of care for AMI (acute myocardial infection) patients." VALUE MEASURES--SELECT A SET OF OUTCOME AND COST MEASURES: Four to 12 outcome and cost measures are sufficient to get started. In the case example, the team chose 1 or more measures for each quadrant of the value compass. An operational definition is a clearly specified method explaining how to measure a variable. Measures in the case example were based on information from the medical record, administrative and financial records, and patient reports and ratings at eight weeks postdischarge. Measurement systems that quantify the quality of processes and results of care are often add-ons to routine care delivery. However, the process of measurement should be intertwined with the process of care delivery so that front-line providers are involved in both managing the patient and measuring the process and related outcomes and costs.

  11. Repeatability, variability and reference values of pulsed wave Doppler echocardiographic measurements in healthy Saanen goats

    PubMed Central

    2012-01-01

    Background Pulsed wave (PW) Doppler echocardiography has become a routine non invasive cardiac diagnostic tool in most species. However, evaluation of intracardiac blood flow requires reference values, which are poorly documented in goats. The aim of this study was to test the repeatability, the variability, and to establish the reference values of PW measurements in healthy adult Saanen goats. Using a standardised PW Doppler echocardiographic protocol, 10 healthy adult unsedated female Saanen goats were investigated three times at one day intervals by the same observer. Mitral, tricuspid, aortic and pulmonary flows were measured from a right parasternal view, and mitral and aortic flows were also measured from a left parasternal view. The difference between left and right side measurements and the intra-observer inter-day repeatability were tested and then the reference values of PW Doppler echocardiographic parameters in healthy adult female Saanen goats were established. Results As documented in other species, all caprine PW Doppler parameters demonstrated a poor inter-day repeatability and a moderate variability. Tricuspid and pulmonary flows were best evaluated on the right side whereas mitral and aortic flows were best obtained on the left side, and reference values are reported for healthy adult Saanen goats. Conclusions PW Doppler echocardiography allows the measurement of intracardiac blood flow indices in goats. The reference values establishment will help interpreting these indices of cardiac function in clinical cardiac cases and developing animal models for human cardiology research. PMID:23067875

  12. SU(2)CMB at high redshifts and the value of H0

    NASA Astrophysics Data System (ADS)

    Hahn, Steffen; Hofmann, Ralf

    2017-07-01

    We investigate a high-z cosmological model to compute the comoving sound horizon rs at baryon-velocity freeze-out towards the end of hydrogen recombination. This model assumes a replacement of the conventional cosmic microwave background (CMB) photon gas by deconfining SU(2) Yang-Mills thermodynamics, three flavours of massless neutrinos (Nν = 3) and a purely baryonic matter sector [no cold dark-matter (CDM)]. The according SU(2) temperature-redshift relation of the CMB is contrasted with recent measurements appealing to the thermal Sunyaev-Zel'dovich effect and CMB-photon absorption by molecular rotation bands or atomic hyperfine levels. Relying on a realistic simulation of the ionization history throughout recombination, we obtain z* = 1693.55 ± 6.98 and zdrag = 1812.66 ± 7.01. Due to considerable widths of the visibility functions in the solutions to the associated Boltzmann hierarchy and Euler equation, we conclude that z* and zdrag overestimate the redshifts for the respective photon and baryon-velocity freeze-out. Realistic decoupling values turn out to be zlf,* = 1554.89 ± 5.18 and zlf, drag = 1659.30 ± 5.48. With rs(zlf, drag) = (137.19 ± 0.45) Mpc and the essentially model independent extraction of rsH0 = constant from low-z data in Bernal, Verde & Riess, we obtain a good match with the value H0 = (73.24 ± 1.74) km s-1 Mpc-1 extracted in Riess et al. by appealing to Cepheid-calibrated Type Ia supernovae, new parallax measurements, stronger constraints on the Hubble flow and a refined computation of distance to NGC 4258 from maser data. We briefly comment on a possible interpolation of our high-z model, invoking percolated and unpercolated U(1) topological solitons of a Planck-scale axion field, to the phenomenologically successful low-z ΛCDM cosmology.

  13. Integrated measurements and modeling of CO2, CH4, and N2O fluxes using soil microsite frequency distributions

    NASA Astrophysics Data System (ADS)

    Davidson, Eric; Sihi, Debjani; Savage, Kathleen

    2017-04-01

    Soil fluxes of greenhouse gases (GHGs) play a significant role as biotic feedbacks to climate change. Production and consumption of carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) are affected by complex interactions of temperature, moisture, and substrate supply, which are further complicated by spatial heterogeneity of the soil matrix. Models of belowground processes of these GHGs should be internally consistent with respect to the biophysical processes of gaseous production, consumption, and transport within the soil, including the contrasting effects of oxygen (O2) as either substrate or inhibitor. We installed automated chambers to simultaneously measure soil fluxes of CO2 (using LiCor-IRGA), CH4, and N2O (using Aerodyne quantum cascade laser) along soil moisture gradients at the Howland Forest in Maine, USA. Measured fluxes of these GHGs were used to develop and validate a merged model. While originally intended for aerobic respiration, the core structure of the Dual Arrhenius and Michaelis-Menten (DAMM) model was modified by adding M-M and Arrhenius functions for each GHG production and consumption process, and then using the same diffusion functions for each GHG and for O2. The area under a soil chamber was partitioned according to a log-normal probability distribution function, where only a small fraction of microsites had high available-C. The probability distribution of soil C leads to a simulated distribution of heterotrophic respiration, which translates to a distribution of O2 consumption among microsites. Linking microsite consumption of O2 with a diffusion model generates microsite concentrations of O2, which then determine the distribution of microsite production and consumption of CH4 and N2O, and subsequently their microsite concentrations using the same diffusion function. At many moisture values, there are some microsites of production and some of consumption for each gas, and the resulting simulated microsite concentrations of CH4

  14. Trojan horse measurement of the 10B(p ,α0)7Be cross section in the energy range from 3 keV to 2.2 MeV

    NASA Astrophysics Data System (ADS)

    Cvetinović, A.; Spitaleri, C.; Spartá, R.; Rapisarda, G. G.; Puglia, S. M. R.; La Cognata, M.; Cherubini, S.; Guardo, G. L.; Gulino, M.; Lamia, L.; Pizzone, R. G.; Romano, S.; Sergi, M. L.; Tumino, A.

    2018-06-01

    The 10B(p ,α0)7Be excitation function has been studied in a wide energy range, from 2.2 MeV down to astrophysical energies, reproducing the cross section above and below the Coulomb barrier in a single experiment. An optimized experimental setup ensured good energy resolution and for the first time a clear separation of α0 and α1 channels of the 10B+2H interaction has been achieved by applying the Trojan Horse method. An improved normalization of the Trojan Horse bare-nucleus astrophysical S (E )-factor to direct data was performed and a value of Ue=391 ±74 eV was obtained for the electron screening potential.

  15. Safeguarding pollinators and their values to human well-being.

    PubMed

    Potts, Simon G; Imperatriz-Fonseca, Vera; Ngo, Hien T; Aizen, Marcelo A; Biesmeijer, Jacobus C; Breeze, Thomas D; Dicks, Lynn V; Garibaldi, Lucas A; Hill, Rosemary; Settele, Josef; Vanbergen, Adam J

    2016-12-08

    Wild and managed pollinators provide a wide range of benefits to society in terms of contributions to food security, farmer and beekeeper livelihoods, social and cultural values, as well as the maintenance of wider biodiversity and ecosystem stability. Pollinators face numerous threats, including changes in land-use and management intensity, climate change, pesticides and genetically modified crops, pollinator management and pathogens, and invasive alien species. There are well-documented declines in some wild and managed pollinators in several regions of the world. However, many effective policy and management responses can be implemented to safeguard pollinators and sustain pollination services.

  16. The Value of CO2-Geothermal Bulk Energy Storage to Reducing CO2 Emissions Compared to Conventional Bulk Energy Storage Technologies

    NASA Astrophysics Data System (ADS)

    Ogland-Hand, J.; Bielicki, J. M.; Buscheck, T. A.

    2016-12-01

    Sedimentary basin geothermal resources and CO2 that is captured from large point sources can be used for bulk energy storage (BES) in order to accommodate higher penetration and utilization of variable renewable energy resources. Excess energy is stored by pressurizing and injecting CO2 into deep, porous, and permeable aquifers that are ubiquitous throughout the United States. When electricity demand exceeds supply, some of the pressurized and geothermally-heated CO2 can be produced and used to generate electricity. This CO2-BES approach reduces CO2 emissions directly by storing CO2 and indirectly by using some of that CO2 to time-shift over-generation and displace CO2 emissions from fossil-fueled power plants that would have otherwise provided electricity. As such, CO2-BES may create more value to regional electricity systems than conventional pumped hydro energy storage (PHES) or compressed air energy storage (CAES) approaches that may only create value by time-shifting energy and indirectly reducing CO2 emissions. We developed and implemented a method to estimate the value that BES has to reducing CO2 emissions from regional electricity systems. The method minimizes the dispatch of electricity system components to meet exogenous demand subject to various CO2 prices, so that the value of CO2 emissions reductions can be estimated. We applied this method to estimate the performance and value of CO2-BES, PHES, and CAES within real data for electricity systems in California and Texas over the course of a full year to account for seasonal fluctuations in electricity demand and variable renewable resource availability. Our results suggest that the value of CO2-BES to reducing CO2 emissions may be as much as twice that of PHES or CAES and thus CO2-BES may be a more favorable approach to energy storage in regional electricity systems, especially those where the topography is not amenable to PHES or the subsurface is not amenable to CAES.

  17. Quantitative measurement of carbon isotopic composition in CO2 gas reservoir by Micro-Laser Raman spectroscopy

    NASA Astrophysics Data System (ADS)

    Li, Jiajia; Li, Rongxi; Zhao, Bangsheng; Guo, Hui; Zhang, Shuan; Cheng, Jinghua; Wu, Xiaoli

    2018-04-01

    The use of Micro-Laser Raman spectroscopy technology for quantitatively determining gas carbon isotope composition is presented. In this study, 12CO2 and 13CO2 were mixed with N2 at various molar fraction ratios to obtain Raman quantification factors (F12CO2 and F13CO2), which provide a theoretical basis for calculating the δ13C value. And the corresponding values were 0.523 (0 < C12CO2/CN2 < 2) and 1.11998 (0 < C13CO2/CN2 < 1.5) respectively. It has shown that the representative Raman peak area can be used for the determination of δ13C values within the relative errors range of 0.076% to 1.154% in 13CO2/12CO2 binary mixtures when F12CO2/F13CO2 is 0.466972625. In addition, measurement of δ13C values by Micro-Laser Raman analysis were carried out on natural CO2 gas from Shengli Oil-field at room temperature under different pressures. The δ13C values obtained by Micro-Laser Raman spectroscopy technology and Isotope Ratio Mass Spectrometry (IRMS) technology are in good agreement with each other, and the relative errors range of δ13C values is 1.232%-6.964%. This research provides a fundamental analysis tool for determining gas carbon isotope composition (δ13C values) quantitatively by using Micro-Laser Raman spectroscopy. Experiment of results demonstrates that this method has the potential for obtaining δ13C values in natural CO2 gas reservoirs.

  18. What's the Value in Value-Added?

    ERIC Educational Resources Information Center

    Duffrin, Elizabeth

    2011-01-01

    A growing number of school districts are adopting "value-added" measures of teaching quality to award bonuses or even tenure. And two competitive federal grants are spurring them on. Districts using value-added data are encouraged by the results. But researchers who support value-added measures advise caution. The ratings, which use a…

  19. A 2.4% DETERMINATION OF THE LOCAL VALUE OF THE HUBBLE CONSTANT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Riess, Adam G.; Scolnic, Dan; Jones, David O.

    We use the Wide Field Camera 3 (WFC3) on the Hubble Space Telescope (HST) to reduce the uncertainty in the local value of the Hubble constant from 3.3% to 2.4%. The bulk of this improvement comes from new near-infrared (NIR) observations of Cepheid variables in 11 host galaxies of recent type Ia supernovae (SNe Ia), more than doubling the sample of reliable SNe Ia having a Cepheid-calibrated distance to a total of 19; these in turn leverage the magnitude-redshift relation based on ∼300 SNe Ia at z < 0.15. All 19 hosts as well as the megamaser system NGC 4258more » have been observed with WFC3 in the optical and NIR, thus nullifying cross-instrument zeropoint errors in the relative distance estimates from Cepheids. Other noteworthy improvements include a 33% reduction in the systematic uncertainty in the maser distance to NGC 4258, a larger sample of Cepheids in the Large Magellanic Cloud (LMC), a more robust distance to the LMC based on late-type detached eclipsing binaries (DEBs), HST observations of Cepheids in M31, and new HST -based trigonometric parallaxes for Milky Way (MW) Cepheids. We consider four geometric distance calibrations of Cepheids: (i) megamasers in NGC 4258, (ii) 8 DEBs in the LMC, (iii) 15 MW Cepheids with parallaxes measured with HST /FGS, HST /WFC3 spatial scanning and/or Hipparcos , and (iv) 2 DEBs in M31. The Hubble constant from each is 72.25 ± 2.51, 72.04 ± 2.67, 76.18 ± 2.37, and 74.50 ± 3.27 km s{sup 1} Mpc{sup 1}, respectively. Our best estimate of H {sub 0} = 73.24 ± 1.74 km s{sup 1} Mpc{sup 1} combines the anchors NGC 4258, MW, and LMC, yielding a 2.4% determination (all quoted uncertainties include fully propagated statistical and systematic components). This value is 3.4 σ higher than 66.93 ± 0.62 km s{sup 1} Mpc{sup 1} predicted by ΛCDM with 3 neutrino flavors having a mass of 0.06 eV and the new Planck data, but the discrepancy reduces to 2.1 σ relative to the prediction of 69.3 ± 0.7 km s{sup 1} Mpc{sup 1} based on

  20. A 2.4% Determination of the Local Value of the Hubble Constant

    NASA Astrophysics Data System (ADS)

    Riess, Adam G.; Macri, Lucas M.; Hoffmann, Samantha L.; Scolnic, Dan; Casertano, Stefano; Filippenko, Alexei V.; Tucker, Brad E.; Reid, Mark J.; Jones, David O.; Silverman, Jeffrey M.; Chornock, Ryan; Challis, Peter; Yuan, Wenlong; Brown, Peter J.; Foley, Ryan J.

    2016-07-01

    We use the Wide Field Camera 3 (WFC3) on the Hubble Space Telescope (HST) to reduce the uncertainty in the local value of the Hubble constant from 3.3% to 2.4%. The bulk of this improvement comes from new near-infrared (NIR) observations of Cepheid variables in 11 host galaxies of recent type Ia supernovae (SNe Ia), more than doubling the sample of reliable SNe Ia having a Cepheid-calibrated distance to a total of 19; these in turn leverage the magnitude-redshift relation based on ˜300 SNe Ia at z < 0.15. All 19 hosts as well as the megamaser system NGC 4258 have been observed with WFC3 in the optical and NIR, thus nullifying cross-instrument zeropoint errors in the relative distance estimates from Cepheids. Other noteworthy improvements include a 33% reduction in the systematic uncertainty in the maser distance to NGC 4258, a larger sample of Cepheids in the Large Magellanic Cloud (LMC), a more robust distance to the LMC based on late-type detached eclipsing binaries (DEBs), HST observations of Cepheids in M31, and new HST-based trigonometric parallaxes for Milky Way (MW) Cepheids. We consider four geometric distance calibrations of Cepheids: (I) megamasers in NGC 4258, (II) 8 DEBs in the LMC, (III) 15 MW Cepheids with parallaxes measured with HST/FGS, HST/WFC3 spatial scanning and/or Hipparcos, and (IV) 2 DEBs in M31. The Hubble constant from each is 72.25 ± 2.51, 72.04 ± 2.67, 76.18 ± 2.37, and 74.50 ± 3.27 km s-1 Mpc-1, respectively. Our best estimate of H 0 = 73.24 ± 1.74 km s-1 Mpc-1 combines the anchors NGC 4258, MW, and LMC, yielding a 2.4% determination (all quoted uncertainties include fully propagated statistical and systematic components). This value is 3.4σ higher than 66.93 ± 0.62 km s-1 Mpc-1 predicted by ΛCDM with 3 neutrino flavors having a mass of 0.06 eV and the new Planck data, but the discrepancy reduces to 2.1σ relative to the prediction of 69.3 ± 0.7 km s-1 Mpc-1 based on the comparably precise combination of WMAP

  1. Can H2CCC be the Carrier of Broad Diffuse Bands?

    NASA Astrophysics Data System (ADS)

    Krełowski, J.; Galazutdinov, G.; Kołos, R.

    2011-07-01

    The recent assignment of two broad diffuse interstellar bands (DIBs) near 4882 and 5450 Å to the propadienylidene (l-C3H2) molecule is examined using a statistically meaningful sample of targets. Our spectra clearly show that the strength ratio of two broad DIBs is strongly variable, contrary to what should be observed if both features are due to l-C3H2, since the proposed transitions are lifetime broadened and start from the same level. Moreover, even in directions where the 4882 DIB and 5450 DIB are strong, the third expected l-C3H2 band, in the 5165-5185 Å region, is absent. Another puzzling characteristic of l-C3H2 as the proposed carrier of both broad diffuse bands is its column density of several 1014 cm-2, inferred from the equivalent width of the 5450 DIB. This value is one order of magnitude higher than N(CH) toward the same objects and two to three orders of magnitude higher than N(H2CCC), measured at radio frequencies in absorption, for comparable samples of the diffuse medium. We conclude that the proposed identification of broad DIBs is unjustified. Based on observations collected at the European Organization for Astronomical Research in the Southern Hemisphere, Chile; programs 073.C-0337(A) and 082.C-0566(A).

  2. 36 CFR 223.64 - Appraisal on a lump-sum value or rate per unit of measure basis.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... costs or selling values subsequent to the rate redetermination which reduce conversion value to less... or rate per unit of measure basis. 223.64 Section 223.64 Parks, Forests, and Public Property FOREST... Contracts Appraisal and Pricing § 223.64 Appraisal on a lump-sum value or rate per unit of measure basis...

  3. Measurement of the 4 S1 /2→6 S1 /2 transition frequency in atomic potassium via direct frequency-comb spectroscopy

    NASA Astrophysics Data System (ADS)

    Stalnaker, J. E.; Ayer, H. M. G.; Baron, J. H.; Nuñez, A.; Rowan, M. E.

    2017-07-01

    We present an experimental determination of the 4 S1 /2→6 S1 /2 transition frequency in atomic potassium 39K, using direct frequency-comb spectroscopy. The output of a stabilized optical frequency comb was used to excite a thermal atomic vapor. The repetition rate of the frequency comb was scanned and the transitions were excited using stepwise two-photon excitation. The center-of-gravity frequency for the transition was found to be νcog=822 951 698.09 (13 ) MHz and the measured hyperfine A coefficient of the 6 S1 /2 state was 21.93 (11 ) MHz. The measurements are in agreement with previous values and represent an improvement by a factor of 700 in the uncertainty of the center-of-gravity measurement.

  4. Measuring Value Added in Higher Education: A Proposed Methodology for Developing a Performance Indicator Based on the Economic Value Added to Graduates

    ERIC Educational Resources Information Center

    Rodgers, Timothy

    2007-01-01

    The 2003 UK higher education White Paper suggested that the sector needed to re-examine the potential of the value added concept. This paper describes a possible methodology for developing a performance indicator based on the economic value added to graduates. The paper examines how an entry-quality-adjusted measure of a graduate's…

  5. Should sensory function after median nerve injury and repair be quantified using two-point discrimination as the critical measure?

    PubMed

    Jerosch-Herold, C

    2000-12-01

    Two-point discrimination (2PD) is widely used for evaluating outcome from peripheral nerve injury and repair. It is the only quantifiable measure used in the British Medical Research Council (MRC) classification that was developed by Highet in 1954. This paper reports the results of a study of 41 patients with complete median nerve lacerations to the wrist or forearm. Two-point discrimination thresholds were assessed together with locognosia (locognosia is the ability to localise a sensory stimulus on the body's surface), tactile gnosis, and touch threshold. Using the MRC classification 29 (71%) patients had a result of S2 or below, 11 (27%) were S3, and only one scored S3+. Patients scored much better on the other tests and showed progressive recovery. It remains too difficult for patients to obtain a measurable threshold value on 2PD and the test therefore lacks responsiveness. The rating of outcome from peripheral nerve repair should not be based solely on 2PD testing and must include other tests of tactile sensibility.

  6. Measuring the value of older people's production: a diary study

    PubMed Central

    2012-01-01

    Background The productive capacity of retired people is usually not valued. However, some retirees produce much more than we might expect. This diary-based study identifies the activities of older people, and suggests some value mechanisms. One question raised is whether it is possible to scale up this diary study into a larger representative study. Methods Diaries kept for one week were collected among 23 older people in the north of Sweden. The texts were analysed with a grounded theory approach; an interplay between ideas and empirical data. Results Some productive activities of older people must be valued as the opportunity cost of time or according to the market value, and others must be valued with the replacement cost. In order to make the choice between these methods, it is important to consider the societal entitlement. When there is no societal entitlement, the first or second method must be used; and when it exists, the third must be used. Conclusions An explicit investigation of the content of the entitlement is needed to justify the choice of valuation method for each activity. In a questionnaire addressing older people's production, each question must be adjusted to the type of production. In order to fully understand this production, it is important to consider the degree of free choice to conduct an activity, as well as health-related quality of life. PMID:22230745

  7. When bad moods may not be so bad: Valuing negative affect is associated with weakened affect-health links.

    PubMed

    Luong, Gloria; Wrzus, Cornelia; Wagner, Gert G; Riediger, Michaela

    2016-04-01

    Bad moods are considered "bad" not only because they may be aversive experiences in and of themselves, but also because they are associated with poorer psychosocial functioning and health. We propose that people differ in their negative affect valuation (NAV; the extent to which negative affective states are valued as pleasant, useful/helpful, appropriate, and meaningful experiences) and that affect-health links are moderated by NAV. These predictions were tested in a life span sample of 365 participants ranging from 14-88 years of age using reports of momentary negative affect and physical well-being (via experience sampling) and assessments of NAV and psychosocial and physical functioning (via computer-assisted personal interviews and behavioral measures of hand grip strength). Our study demonstrated that the more individuals valued negative affect, the less pronounced (and sometimes even nonexistent) were the associations between everyday experiences of negative affect and a variety of indicators of poorer psychosocial functioning (i.e., emotional health problems, social integration) and physical health (i.e., number of health conditions, health complaints, hand grip strength, momentary physical well-being). Exploratory analyses revealed that valuing positive affect was not associated with the analogous moderating effects as NAV. These findings suggest that it may be particularly important to consider NAV in models of affect-health links. (c) 2016 APA, all rights reserved).

  8. Longitudinal double-spin asymmetry A1p and spin-dependent structure function g1p of the proton at small values of x and Q2

    NASA Astrophysics Data System (ADS)

    Aghasyan, M.; Alexeev, M. G.; Alexeev, G. D.; Amoroso, A.; Andrieux, V.; Anfimov, N. V.; Anosov, V.; Antoshkin, A.; Augsten, K.; Augustyniak, W.; Austregesilo, A.; Azevedo, C. D. R.; Badełek, B.; Balestra, F.; Ball, M.; Barth, J.; Beck, R.; Bedfer, Y.; Bernhard, J.; Bicker, K.; Bielert, E. R.; Birsa, R.; Bodlak, M.; Bordalo, P.; Bradamante, F.; Bressan, A.; Büchele, M.; Burtsev, V. E.; Capozza, L.; Chang, W.-C.; Chatterjee, C.; Chiosso, M.; Choi, I.; Chumakov, A. G.; Chung, S.-U.; Cicuttin, A.; Crespo, M. L.; Dalla Torre, S.; Dasgupta, S. S.; Dasgupta, S.; Denisov, O. Yu.; Dhara, L.; Donskov, S. V.; Doshita, N.; Dreisbach, Ch.; Dünnweber, W.; Dusaev, R. R.; Dziewiecki, M.; Efremov, A.; Eversheim, P. D.; Faessler, M.; Ferrero, A.; Finger, M.; Finger, M.; Fischer, H.; Franco, C.; Du Fresne von Hohenesche, N.; Friedrich, J. M.; Frolov, V.; Fuchey, E.; Gautheron, F.; Gavrichtchouk, O. P.; Gerassimov, S.; Giarra, J.; Giordano, F.; Gnesi, I.; Gorzellik, M.; Grasso, A.; Gridin, A.; Grosse Perdekamp, M.; Grube, B.; Grussenmeyer, T.; Guskov, A.; Hahne, D.; Hamar, G.; von Harrach, D.; Heinsius, F. H.; Heitz, R.; Herrmann, F.; Horikawa, N.; D'Hose, N.; Hsieh, C.-Y.; Huber, S.; Ishimoto, S.; Ivanov, A.; Iwata, T.; Jary, V.; Joosten, R.; Jörg, P.; Kabuß, E.; Kerbizi, A.; Ketzer, B.; Khaustov, G. V.; Khokhlov, Yu. A.; Kisselev, Yu.; Klein, F.; Koivuniemi, J. H.; Kolosov, V. N.; Kondo, K.; Königsmann, K.; Konorov, I.; Konstantinov, V. F.; Kotzinian, A. M.; Kouznetsov, O. M.; Kral, Z.; Krämer, M.; Kremser, P.; Krinner, F.; Kroumchtein, Z. V.; Kulinich, Y.; Kunne, F.; Kurek, K.; Kurjata, R. P.; Kuznetsov, I. I.; Kveton, A.; Lednev, A. A.; Levchenko, E. A.; Levillain, M.; Levorato, S.; Lian, Y.-S.; Lichtenstadt, J.; Longo, R.; Lyubovitskij, V. E.; Maggiora, A.; Magnon, A.; Makins, N.; Makke, N.; Mallot, G. K.; Mamon, S. A.; Marianski, B.; Martin, A.; Marzec, J.; Matoušek, J.; Matsuda, H.; Matsuda, T.; Meshcheryakov, G. V.; Meyer, M.; Meyer, W.; Mikhailov, Yu. V.; Mikhasenko, M.; Mitrofanov, E.; Mitrofanov, N.; Miyachi, Y.; Moretti, A.; Nagaytsev, A.; Nerling, F.; Neyret, D.; Nový, J.; Nowak, W.-D.; Nukazuka, G.; Nunes, A. S.; Olshevsky, A. G.; Orlov, I.; Ostrick, M.; Panzieri, D.; Parsamyan, B.; Paul, S.; Peng, J.-C.; Pereira, F.; Pešek, M.; Pešková, M.; Peshekhonov, D. V.; Pierre, N.; Platchkov, S.; Pochodzalla, J.; Polyakov, V. A.; Pretz, J.; Quaresma, M.; Quintans, C.; Ramos, S.; Regali, C.; Reicherz, G.; Riedl, C.; Rogacheva, N. S.; Ryabchikov, D. I.; Rybnikov, A.; Rychter, A.; Salac, R.; Samoylenko, V. D.; Sandacz, A.; Santos, C.; Sarkar, S.; Savin, I. A.; Sawada, T.; Sbrizzai, G.; Schiavon, P.; Schmidt, K.; Schmieden, H.; Schönning, K.; Seder, E.; Selyunin, A.; Silva, L.; Sinha, L.; Sirtl, S.; Slunecka, M.; Smolik, J.; Srnka, A.; Steffen, D.; Stolarski, M.; Subrt, O.; Sulc, M.; Suzuki, H.; Szabelski, A.; Szameitat, T.; Sznajder, P.; Tasevsky, M.; Tessaro, S.; Tessarotto, F.; Thiel, A.; Tomsa, J.; Tosello, F.; Tskhay, V.; Uhl, S.; Vasilishin, B. I.; Vauth, A.; Veloso, J.; Vidon, A.; Virius, M.; Wallner, S.; Weisrock, T.; Wilfert, M.; Windmolders, R.; Ter Wolbeek, J.; Zaremba, K.; Zavada, P.; Zavertyaev, M.; Zemlyanichkina, E.; Ziembicki, M.; Compass Collaboration

    2018-06-01

    We present a precise measurement of the proton longitudinal double-spin asymmetry A1p and the proton spin-dependent structure function g1p at photon virtualities 0.006(GeV / c) 2 2 < 1(GeV / c) 2 in the Bjorken x range of 4 ×10-5 < x < 4 ×10-2. The results are based on data collected by the COMPASS Collaboration at CERN using muon beam energies of 160GeV and 200GeV. The statistical precision is more than tenfold better than that of the previous measurement in this region. In the whole range of x, the measured values of A1p and g1p are found to be positive. It is for the first time that spin effects are found at such low values of x.

  9. Optimum pelvic incidence minus lumbar lordosis value can be determined by individual pelvic incidence.

    PubMed

    Inami, Satoshi; Moridaira, Hiroshi; Takeuchi, Daisaku; Shiba, Yo; Nohara, Yutaka; Taneichi, Hiroshi

    2016-11-01

    Adult spinal deformity (ASD) classification showing that ideal pelvic incidence minus lumbar lordosis (PI-LL) value is within 10° has been received widely. But no study has focused on the optimum level of PI-LL value that reflects wide variety in PI among patients. This study was conducted to determine the optimum PI-LL value specific to an individual's PI in postoperative ASD patients. 48 postoperative ASD patients were recruited. Spino-pelvic parameters and Oswestry Disability Index (ODI) were measured at the final follow-up. Factors associated with good clinical results were determined by stepwise multiple regression model using the ODI. The patients with ODI under the 75th percentile cutoff were designated into the "good" health related quality of life (HRQOL) group. In this group, the relationship between the PI-LL and PI was assessed by regression analysis. Multiple regression analysis revealed PI-LL as significant parameters associated with ODI. Thirty-six patients with an ODI <22 points (75th percentile cutoff) were categorized into a good HRQOL group, and linear regression models demonstrated the following equation: PI-LL = 0.41PI-11.12 (r = 0.45, P = 0.0059). On the basis of this equation, in the patients with a PI = 50°, the PI-LL is 9°. Whereas in those with a PI = 30°, the optimum PI-LL is calculated to be as low as 1°. In those with a PI = 80°, PI-LL is estimated at 22°. Consequently, an optimum PI-LL is inconsistent in that it depends on the individual PI.

  10. Measuring the volume of uterine fibroids using 2- and 3-dimensional ultrasound and comparison with histopathology.

    PubMed

    Zivković, Nikica; Zivković, Kreiimir; Despot, Albert; Paić, Josip; Zelić, Ana

    2012-12-01

    The aim of this study was clinical testing of the reliability and usability of three-dimensional (3D) and two-dimensional (2D) ultrasound (US) technology. The ultimate aim and purpose of this study was to establish ultrasound methods, standards and protocols for determining the volume of any gynecologic organ or tumor. The study included 31 women in reproductive age and postmenopause. All patients were examined with a RIC 5-9 3D-endovaginal probe (4.3-7.5 MHz) on a Voluson 730 Pro ultrasound device. The volume of myomas was measured by using the existing 2D and 3D ultrasound methods on the above mentioned device. All patients underwent myomectomy or hysterectomy due to clinically and ultrasonographically diagnosed uterine myomas indicating operative intervention. After the operation, the pathologist determined the volume of removed myomas by measuring them in a gauge bowl containing water, i.e. using Archimedes' principle (lift), serving as the control group with histopathologic diagnosis. A total of 155 myoma volumes were processed on 2D display, 31 myoma volumes were preoperatively measured on 3D display and 31 myoma volumes were measured by the pathologist. The values of US measurements for each US method were expressed as mean value of all measurements of myoma volumes. Statistical processing of the results and Student's t-test for independent samples revealed that the 2nd examined US method (measuring of myoma by using an ellipse and the longer tumor diameter) and 4th examined US method (measuring of myoma by using the longer and shorter tumor diameters together with establishing their mean values) in 2D US technique, as well as the 6th examined US method in 3D US technique showed no significant measurement differences in comparison with control measurement in a gauge bowl containing water (p < 0.05), indicating acceptability of the US methods for verifying tumor volumes. The standard error in determining the volume of myomas by the above US methods varied

  11. Electrode effects in dielectric spectroscopy measurements on (Nb+In) co-doped TiO2

    NASA Astrophysics Data System (ADS)

    Crandles, D. A.; Yee, S. M. M.; Savinov, M.; Nuzhnyy, D.; Petzelt, J.; Kamba, S.; Prokeš, J.

    2016-04-01

    Recently, several papers reported the discovery of giant permittivity and low dielectric loss in (Nb+In) co-doped TiO2. A series of tests was performed which included the measurement of the frequency dependence of the dielectric permittivity and alternating current (ac) conductivity of co-doped (Nb+In)TiO2 as a function of electrode type, sample thickness, and temperature. The data suggest that the measurements are strongly affected by the electrodes. The consistency between four-contact van der Pauw direct current conductivity measurements and bulk conductivity values extracted from two-contact ac conductivity measurements suggest that the values of colossal permittivity are, at least in part, a result of Schottky barrier depletion widths that depend on electrode type and temperature.

  12. When Not All That Counts Can Be Counted: Economic Evaluations And The Value Of Vaccination.

    PubMed

    Schwartz, Jason L; Mahmoud, Adel

    2016-02-01

    With vaccination efforts forced to compete for scarce resources at a time when national health budgets, global health resources, and the global donor community are facing considerable strains, advocates of vaccines have sought to better identify, measure, and articulate the value of vaccination. Critics of current analyses of the value of vaccination argue that a broader view is required, one that includes the additional economic benefits of vaccines or acknowledges the social and ethical aims advanced by vaccination programs. Much of this work has paid inadequate attention to the need to apply any expanded view of value consistently across medical interventions, to the close and complex integration of vaccination efforts with other health initiatives, and to the fact that subjectivity and judgments are present in quantitative and qualitative evidence alike. To fully realize the value of vaccination, far more attention, investment, and research are required to better understand the deliberations and decision-making processes by which any kind of evidence is translated into policy. Project HOPE—The People-to-People Health Foundation, Inc.

  13. Dual-Pump Coherent Anti-Stokes Raman Scattering Temperature and CO2 Concentration Measurements

    NASA Technical Reports Server (NTRS)

    Lucht, Robert P.; Velur-Natarajan, Viswanathan; Carter, Campbell D.; Grinstead, Keith D., Jr.; Gord, James R.; Danehy, Paul M.; Fiechtner, G. J.; Farrow, Roger L.

    2003-01-01

    Measurements of temperature and CO2 concentration using dual-pump coherent anti-Stokes Raman scattering, (CARS) are described. The measurements were performed in laboratory flames,in a room-temperature gas cell, and on an engine test stand at the U.S. Air Force Research Laboratory, Wright-Patterson Air Force Base. A modeless dye laser, a single-mode Nd:YAG laser, and an unintensified back-illuminated charge-coupled device digital camera were used for these measurements. The CARS measurements were performed on a single-laser-shot basis. The standard deviations of the temperatures and CO2 mole fractions determined from single-shot dual-pump CARS spectra in steady laminar propane/air flames were approximately 2 and 10% of the mean values of approximately 2000 K and 0.10, respectively. The precision and accuracy of single-shot temperature measurements obtained from the nitrogen part of the dual-pump CARS system were investigated in detail in near-adiabatic hydrogen/air/CO2 flames. The precision of the CARS temperature measurements was found to be comparable to the best results reported in the literature for conventional two-laser, single-pump CARS. The application of dual-pump CARS for single-shot measurements in a swirl-stabilized combustor fueled with JP-8 was also demonstrated.

  14. 48 CFR 1852.234-2 - Earned Value Management System.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Earned Value Management... and Clauses 1852.234-2 Earned Value Management System. As prescribed in 1834.203-70(b) insert the following clause: Earned Value Management System (NOV 2006) (a) In the performance of this contract, the...

  15. 48 CFR 1852.234-2 - Earned Value Management System.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Earned Value Management... and Clauses 1852.234-2 Earned Value Management System. As prescribed in 1834.203-70(b) insert the following clause: Earned Value Management System (NOV 2006) (a) In the performance of this contract, the...

  16. Can in vivo surface dental enamelmicrobiopsies be used to measure remote lead exposure?

    PubMed

    Olympio, Kelly Polido Kaneshiro; Huila, Manuel Fernando Gonzalez; de Almeida Baldini Cardoso, Cristiane; da Silva Ferreira, Ana Paula Sacone; Ortiz, Adrielly Garcia; Toma, Henrique Eisi; da Silva, Ricardo Henrique Alves; Luz, Maciel Santos; Cardoso, Maria Regina Alves; Kelmer, Gislayne Aparecida Rodrigues; de Oliveira, Pedro Vitoriano; Bechara, Etelvino José Henriques; Günther, Wanda Maria Risso; Buzalaf, Marília Afonso Rabelo

    2018-04-01

    Measuring lead in the surface dental enamel (SDE) using biopsies is a rapid, safe, and painless procedure. The dental enamel lead levels (DELLs) decrease from the outermost superficial layer to the inner layer of dental enamel, which becomes crucial for the biopsy depth (BD) measurement. However, whether the origin of lead found in SDE is fully endogenous is not yet established. There is also controversy about the biopsy protocol. The aims of this study were to investigate if DELLs are altered by extrinsic contamination (A) and to evaluate the real geometric figure formed by the erosion provoked by biopsy procedure and the respective BD in SDE (B). To accomplish the aim A, lead from 90 bovine incisor crowns lead was determined by graphite furnace atomic absorption spectrometer as a function of exposure time and lead concentration. Two biopsies were performed in each tooth, before and after lead exposure. Six 15-tooth groups differed by exposure time (1 or 30 min) and lead concentrations (A. 0 mg/L-placebo, B. 0.01 mg/L-standard for drinking water, or C. 0.06 mg/L-concentration found in contaminated groundwater). Phosphorus was determined by an inductively coupled plasm optical emission spectrometer to quantify the enamel removed. To compare intakes/losses of lead in SDE among the groups, values of DELL differences between before and after lead exposure were compared by ANOVA (p < 0.05). To attain the objective B, one extracted human permanent tooth was studied by confocal Raman microscopy. Lead measurements and the surface profile were determined. There was no difference in DELL among the groups (p = 0.964). The biopsy bottom surface area, analyzed by microscopy, showed an irregular area, with regions of peaks and valleys, where areas with depth ranging from 0.2 (peaks) to 1.8 μm (valleys) (± 0.1 μm) could be found. BD carried out in vivo is commonly calculated using the cylinder height formula. The real BD was shown to be very similar to already

  17. Measurement of CO 2, CO, SO 2, and NO emissions from coal-based thermal power plants in India

    NASA Astrophysics Data System (ADS)

    Chakraborty, N.; Mukherjee, I.; Santra, A. K.; Chowdhury, S.; Chakraborty, S.; Bhattacharya, S.; Mitra, A. P.; Sharma, C.

    Measurements of CO 2 (direct GHG) and CO, SO 2, NO (indirect GHGs) were conducted on-line at some of the coal-based thermal power plants in India. The objective of the study was three-fold: to quantify the measured emissions in terms of emission coefficient per kg of coal and per kWh of electricity, to calculate the total possible emission from Indian thermal power plants, and subsequently to compare them with some previous studies. Instrument IMR 2800P Flue Gas Analyzer was used on-line to measure the emission rates of CO 2, CO, SO 2, and NO at 11 numbers of generating units of different ratings. Certain quality assurance (QA) and quality control (QC) techniques were also adopted to gather the data so as to avoid any ambiguity in subsequent data interpretation. For the betterment of data interpretation, the requisite statistical parameters (standard deviation and arithmetic mean) for the measured emissions have been also calculated. The emission coefficients determined for CO 2, CO, SO 2, and NO have been compared with their corresponding values as obtained in the studies conducted by other groups. The total emissions of CO 2, CO, SO 2, and NO calculated on the basis of the emission coefficients for the year 2003-2004 have been found to be 465.667, 1.583, 4.058, and 1.129 Tg, respectively.

  18. Platinum catalytic effect on oxygen fugacity of CO 2H 2 gas mixtures measured with ZrO 2 oxygen sensor at 105 Pa from 1300 to 700°C

    NASA Astrophysics Data System (ADS)

    Miyamoto, M.; Mikouchi, T.

    1996-08-01

    The oxygen fugacity of CO 2H 2 gas mixtures were measured with a ZrO 2 oxygen sensor at high temperatures in a furnace. We confirmed that the oxygen fugacity values measured by the ZrO 2 cell are more reducing than those of the CO 2H 2 gas mixtures calculated by using JANAF data at temperatures below 1150°C as was previously reported by Huebner (1975). We successfully decreased the deviation of the measured oxygen-fugacity value from the calculated one down to temperature of 800°C by using a Pt catalyst. Our results suggest that the deviation is probably due to incomplete equilibration of the gases.

  19. Relevance of methods and standards for the assessment of measurement system performance in a High-Value Manufacturing Industry

    NASA Astrophysics Data System (ADS)

    Loftus, Pete; Giudice, Seb

    2014-08-01

    Measurements underpin the engineering decisions that allow products to be designed, manufactured, operated, and maintained. Therefore, the quality of measured data needs to be systematically assured to allow decision makers to proceed with confidence. The use of standards is one way of achieving this. This paper explores the relevance of international documentary standards to the assessment of measurement system capability in High Value Manufacturing (HVM) Industry. An internal measurement standard is presented which supplements these standards and recommendations are made for a cohesive effort to develop the international standards to provide consistency in such industrial applications.

  20. Direct measurements of unimolecular and bimolecular reaction kinetics of the Criegee intermediate (CH 3) 2COO

    DOE PAGES

    Chhantyal-Pun, Rabi; Welz, Oliver; Savee, John D.; ...

    2016-10-18

    Here, the Criegee intermediate acetone oxide, (CH 3) 2COO, is formed by laser photolysis of 2,2-diiodopropane in the presence of O 2 and characterized by synchrotron photoionization mass spectrometry and by cavity ring-down ultraviolet absorption spectroscopy. The rate coefficient of the reaction of the Criegee intermediate with SO 2 was measured using photoionization mass spectrometry and pseudo-first-order methods to be (7.3 ± 0.5) × 10 –11 cm 3 s –1 at 298 K and 4 Torr and (1.5 ± 0.5) × 10 –10 cm 3 s –1 at 298 K and 10 Torr (He buffer). These values are similar tomore » directly measured rate coefficients of anti-CH 3CHOO with SO 2, and in good agreement with recent UV absorption measurements. The measurement of this reaction at 293 K and slightly higher pressures (between 10 and 100 Torr) in N 2 from cavity ring-down decay of the ultraviolet absorption of (CH 3) 2COO yielded even larger rate coefficients, in the range (1.84 ± 0.12) × 10 –10 to (2.29 ± 0.08) × 10 –10 cm 3 s –1. Photoionization mass spectrometry measurements with deuterated acetone oxide at 4 Torr show an inverse deuterium kinetic isotope effect, kH/kD = (0.53 ± 0.06), for reactions with SO 2, which may be consistent with recent suggestions that the formation of an association complex affects the rate coefficient. The reaction of (CD3)2COO with NO2 has a rate coefficient at 298 K and 4 Torr of (2.1 ± 0.5) × 10 –12 cm 3 s –1 (measured with photoionization mass spectrometry), again similar to rate for the reaction of anti-CH 3CHOO with NO 2. Cavity ring-down measurements of the acetone oxide removal without added reagents display a combination of first- and second-order decay kinetics, which can be deconvolved to derive values for both the self-reaction of (CH 3) 2COO and its unimolecular thermal decay. The inferred unimolecular decay rate coefficient at 293 K, (305 ± 70) s –1, is similar to determinations from ozonolysis. The present measurements confirm the large

  1. 25 CFR 39.807 - How will the Student Unit Value be adjusted annually?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Labor. (b) If the student unit value amount is not fully funded, the schools will receive their pro rata... 25 Indians 1 2011-04-01 2011-04-01 false How will the Student Unit Value be adjusted annually? 39.807 Section 39.807 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION THE INDIAN...

  2. Prognostic Value of Lymphocyte G Protein-Coupled Receptor Kinase-2 Protein Levels in Patients With Heart Failure

    PubMed Central

    Rengo, Giuseppe; Pagano, Gennaro; Filardi, Pasquale Perrone; Femminella, Grazia Daniela; Parisi, Valentina; Cannavo, Alessandro; Liccardo, Daniela; Komici, Klara; Gambino, Giuseppina; D’Amico, Maria Loreta; de Lucia, Claudio; Paolillo, Stefania; Trimarco, Bruno; Vitale, Dino Franco; Ferrara, Nicola; Koch, Walter J; Leosco, Dario

    2016-01-01

    Rationale Sympathetic nervous system (SNS) hyperactivity is associated with poor prognosis in patients with HF, yet routine assessment of SNS activation is not recommended for clinical practice. Myocardial G protein-coupled receptor kinase 2 (GRK2) is up-regulated in heart failure (HF) patients, causing dysfunctional β-adrenergic receptor signaling. Importantly, myocardial GRK2 levels correlate with levels found in peripheral lymphocytes of HF patients. Objective The independent prognostic value of blood GRK2 measurements in HF patients has never been investigated, thus, the purpose of the present study was to evaluate whether lymphocyte GRK2 levels predict clinical outcome in HF patients. Methods and Results We prospectively studied 257 HF patients with mean left ventricular ejection fraction (LVEF) of 31.4±8.5%. At the time of enrollment, plasma norepinephrine, serum NT-proBNP and lymphocyte GRK2 levels, as well as clinical and instrumental variables were measured. The prognostic value of GRK2 to predict cardiovascular (CV) death and all-cause mortality was assessed using the Cox proportional hazard model including demographic, clinical, instrumental and laboratory data. Over a mean follow-up period of 37.5±20.2 months (range: 3–60 months) there were 102 CV deaths. Age, LVEF, NYHA class, Chronic Obstructive Pulmonary Disease, Chronic Kidney Disease, N-terminal-pro Brain Natriuretic Peptide, and lymphocyte GRK2 protein levels were independent predictors of CV mortality in HF patients. GRK2 levels showed an additional prognostic and clinical value over demographic and clinical variables. The independent prognostic value of lymphocyte GRK2 levels was also confirmed for all-cause mortality. Conclusion Lymphocyte GRK2 protein levels can independently predict prognosis in patients with HF. PMID:26884616

  3. 2 CFR 200.470 - Taxes (including Value Added Tax).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Taxes (including Value Added Tax). 200.470... Cost § 200.470 Taxes (including Value Added Tax). (a) For states, local governments and Indian tribes... Federal government for the taxes, interest, and penalties. (c) Value Added Tax (VAT) Foreign taxes charged...

  4. [Value of R2(*) in evaluating the biological behavior of primary hepatocellular carcinoma].

    PubMed

    Tian, S F; Liu, A L; Liu, J H; Li, Y; Liu, X D; Huang, K; Song, Q W; Xu, M Z; Guo, W Y

    2016-04-19

    To investigate the correlation between R2(*) value of enhanced T2 star-weighted angiography (ESWAN) sequence and primary hepatocellular carcinoma infiltration and tumor thrombus, and investigate the biological behavior of HCC. A total of 221 cases of patients' imaging data with MRI examination(including ESWAN sequence) diagnosed as primary HCC were retrospectively analyzed.All the patients were collected from January 2014 to September 2015 in the First Affiliated Hospital of Dalian Medical University.The differences of R2(*) values in different MR types of HCC were analyzed.All patients were divided into infiltration group and non-infiltration group, tumor thrombus group and non-tumor thrombus group, the R2(*) values of the paired groups were compared.The diagnostic efficiency of R2(*) in HCC infiltration and tumor thrombus were evaluated by ROC curve, and to find out the threshold values. The MR types of 221 patients included 90 cases of nodular type, 62 cases of massive type, 69 cases of diffuse type.70 patients had tumor thrombus.The R2(*) values of different MR types were (21.82±8.52), (24.17±8.84)and (34.45±11.73) Hz, respectively.There was no statistically significant difference between the nodular and the massive types (P=0.144), while the difference between the nodular and diffuse type, the massive and diffuse types were statistically significant(P=0.000). The R2(*) values of infiltration group and non-infiltration group were (34.45±11.73) and (22.78±8.70) Hz , the R2(*) values of tumor thrombus group and non-tumor thrombus group were (31.20±12.17) and (24.21±9.90) Hz, the difference also had statistically significant(t=7.397 and 4.534, P=0.000 and 0.000). The AUC of R2(*) values for infiltration and tumor thrombus were 0.804, 0.681. R2(*) ≥24.68 Hz was the threshold value to diagnose the infiltration and tumor thrombus. R2(*) value can be used as a MR non-enhancement quantitative index to evaluate the biological behavior of HCC.

  5. NO2 DOAS Measurements of Traffic Emissions by Chasing Cars

    NASA Astrophysics Data System (ADS)

    Zhu, Ying; Lipkowitsch, Ivo; Chan, Ka Lok; Bräu, Melanie; Wenig, Mark

    2016-04-01

    On this poster we present NO2 measurements using a Cavity-Enhanced DOAS on a measurement bus which we used to chase other vehicles to measure their NO2 emissions. Emissions of nitrogen oxides from on-road vehicles have received highly attention recently due to the increasing trend of ambient NOx level. It is particularly important to identify and quantify the direct emission and secondary formation of NO2 contributed by traffic emissions, in order to study the impact to the local air quality. We sampled on-road emissions in different environments and different driving conditions (e.g. urban, highway, different speeds). We analyse the data set in terms of spatial and temporal variability to search for temporal and spatial patterns. We present mean values sorted for different vehicle types, distance to the target car and travelling speeds to provide an emission data base from this measurement study.

  6. Weak values of spin and momentum in atomic systems.

    NASA Astrophysics Data System (ADS)

    Flack, Robert; Hiley, Basil; Barker, Peter; Monachello, Vincenzo; Morley, Joel

    2017-04-01

    Weak values have a long history and were first considered by Landau and London in connection with superfluids. Hirschfelder called them sub-observables and Dirac anticipatied them when discussing non-commutative geometry in quantum mechanics. The idea of a weak value has returned to prominence due to Aharonov, Albert and Vaidman showing how they can be measured. They are not eigenvalues of the system and can not be measured by a collapse of the wave function with the traditional Von Neumann (strong) measurement which is a single stage process. In contrast the weak measurement process has three stages; preselection, weak stage and finally a post selection. Although weak values have been observed using photons and neutrons, we are building two experiments to observe weak values of spin and momentum in atomic systems. For spin we are following the method outlined by Duck et al which is a variant on the original Stern-Gerlach experiment using a metastable, 23S1 , form of helium. For momentum we are using a method similar to that used by Kocsis with excited argon atoms in the 3P2 state, passing through a 2-slit interferometer. The design, simulation and re John Fetzer Memorial Trust.

  7. Life balance and well-being: testing a novel conceptual and measurement approach.

    PubMed

    Sheldon, Kennon M; Cummins, Robert; Kamble, Shanmukh

    2010-08-01

    Although a balanced life has always been viewed as desirable, there are problems with extant conceptualizations and measures of this construct. Here we introduce 2 new life-balance measures, based on time-use profiles, that address these problems. One defines life balance as objectively equitable time use across multiple life domains, and the other defines life balance as low subjective discrepancy between actual and ideal time-use profiles. Study 1 finds that both measures predict concurrent well-being, in both U.S. and Indian samples. Study 2 shows that fluctuations in balance predict fluctuations in well-being over a 3-week period. Study 3 replicates the Study 1 findings using a different time assessment technique, based on the Day Reconstruction Method. Study 4 assigns participants the month-long goal of enhancing their life balance, finding that those who achieve this goal enhance their well-being. In all 4 studies, the balance effects on well-being were mediated by psychological need satisfaction associated with balance.

  8. SO2 plume height retrieval from direct fitting of GOME-2 backscattered radiance measurements

    NASA Astrophysics Data System (ADS)

    van Gent, J.; Spurr, R.; Theys, N.; Lerot, C.; Brenot, H.; Van Roozendael, M.

    2012-04-01

    The use of satellite measurements for SO2 monitoring has become an important aspect in the support of aviation control. Satellite measurements are sometimes the only information available on SO2 concentrations from volcanic eruption events. The detection of SO2 can furthermore serve as a proxy for the presence of volcanic ash that poses a possible hazard to air traffic. In that respect, knowledge of both the total vertical column amount and the effective altitude of the volcanic SO2 plume is valuable information to air traffic control. The Belgian Institute for Space Aeronomy (BIRA-IASB) hosts the ESA-funded Support to Aviation Control Service (SACS). This system provides Volcanic Ash Advisory Centers (VAACs) worldwide with near real-time SO2 and volcanic ash data, derived from measurements from space. We present results from our algorithm for the simultaneous retrieval of total vertical columns of O3 and SO2 and effective SO2 plume height from GOME-2 backscattered radiance measurements. The algorithm is an extension to the GODFIT direct fitting algorithm, initially developed at BIRA-IASB for the derivation of improved total ozone columns from satellite data. The algorithm uses parameterized vertical SO2 profiles which allow for the derivation of the peak height of the SO2 plume, along with the trace gas total column amounts. To illustrate the applicability of the method, we present three case studies on recent volcanic eruptions: Merapi (2010), Grímsvotn (2011), and Nabro (2011). The derived SO2 plume altitude values are validated with the trajectory model FLEXPART and with aerosol altitude estimations from the CALIOP instrument on-board the NASA A-train CALIPSO platform. We find that the effective plume height can be obtained with a precision as fine as 1 km for moderate and strong volcanic events. Since this is valuable information for air traffic, we aim at incorporating the plume height information in the SACS system.

  9. Quantitative measurement of carbon isotopic composition in CO2 gas reservoir by Micro-Laser Raman spectroscopy.

    PubMed

    Li, Jiajia; Li, Rongxi; Zhao, Bangsheng; Guo, Hui; Zhang, Shuan; Cheng, Jinghua; Wu, Xiaoli

    2018-04-15

    The use of Micro-Laser Raman spectroscopy technology for quantitatively determining gas carbon isotope composition is presented. In this study, 12 CO 2 and 13 CO 2 were mixed with N 2 at various molar fraction ratios to obtain Raman quantification factors (F 12CO2 and F 13CO2 ), which provide a theoretical basis for calculating the δ 13 C value. And the corresponding values were 0.523 (02 /C N2 <2) and 1.11998 (02 /C N2 <1.5) respectively. It has shown that the representative Raman peak area can be used for the determination of δ 13 C values within the relative errors range of 0.076% to 1.154% in 13 CO 2 / 12 CO 2 binary mixtures when F 12CO2 /F 13CO2 is 0.466972625. In addition, measurement of δ 13 C values by Micro-Laser Raman analysis were carried out on natural CO 2 gas from Shengli Oil-field at room temperature under different pressures. The δ 13 C values obtained by Micro-Laser Raman spectroscopy technology and Isotope Ratio Mass Spectrometry (IRMS) technology are in good agreement with each other, and the relative errors range of δ 13 C values is 1.232%-6.964%. This research provides a fundamental analysis tool for determining gas carbon isotope composition (δ 13 C values) quantitatively by using Micro-Laser Raman spectroscopy. Experiment of results demonstrates that this method has the potential for obtaining δ 13 C values in natural CO 2 gas reservoirs. Copyright © 2018. Published by Elsevier B.V.

  10. A comparison of airborne wake vortex detection measurements with values predicted from potential theory

    NASA Technical Reports Server (NTRS)

    Stewart, Eric C.

    1991-01-01

    An analysis of flight measurements made near a wake vortex was conducted to explore the feasibility of providing a pilot with useful wake avoidance information. The measurements were made with relatively low cost flow and motion sensors on a light airplane flying near the wake vortex of a turboprop airplane weighing approximately 90000 lbs. Algorithms were developed which removed the response of the airplane to control inputs from the total airplane response and produced parameters which were due solely to the flow field of the vortex. These parameters were compared with values predicted by potential theory. The results indicated that the presence of the vortex could be detected by a combination of parameters derived from the simple sensors. However, the location and strength of the vortex cannot be determined without additional and more accurate sensors.

  11. Glucose pump test can be used to measure blood flow rate of native arteriovenous fistula in chronic hemodialysis.

    PubMed

    Yavuz, Y C; Selcuk, N Y; Altıntepe, L; Güney, I; Yavuz, S

    2018-01-01

    In chronic hemodialysis patients, the low flow of vascular access may leads to inadequate dialysis, increased rate of hospitalization, morbidity, and mortality. It was found that surveillance should be performed for native arteriovenous (AV) should not be performed for AV graft in various studies. However, surveillance was done in graft AV fistulas in most studies. Doppler ultrasonography (US) was suggested for surveillance of AV fistulas by the last vascular access guideline of National Kidney Foundation Disease Outcomes Quality Initiative (NKF KDOQI). The aim of study is to determine whether glucose pump test (GPT) is used for surveillance of native AV fistulas by using Doppler US as reference. In 93 chronic hemodialysis patients with native AV fistula, blood flow rates were measured by Doppler US and GPT. For GPT, glucose was infused to 16 mL/min by pump and was measured at basal before the infusion and 11 s after the start of the infusion by glucometer. Doppler US was done by an expert radiologist. Used statistical tests were Mann-Whitney U test, Friedman test, regression analysis, and multiple regression analysis. Median values of blood flow rates measured by GPT (707 mL/min) and by Doppler US (700 mL/min) were not different (Z = 0.414, P = 0.678). Results of GPT and Doppler US measurements were positive correlate by regression analysis. The mean GPT value of diabetic patients (n = 39; 908 mL/min) was similar to that of nondiabetic patients (n = 54; 751 mL/min; Z = 1.31, P = 0.188). GPT values measured at three different dialysis session did not differ from each other that by Friedman test (F = 0.92, P = 0.39). This showed that GPT was stable and reliable. Glucose pump test can be used to measure blood flow rate of native AV fistula. GPT is an accurate and reliable test.

  12. Value-Added Measures in Education: What Every Educator Needs to Know

    ERIC Educational Resources Information Center

    Harris, Douglas N.

    2011-01-01

    In "Value-Added Measures in Education", Douglas N. Harris takes on one of the most hotly debated topics in education. Drawing on his extensive work with schools and districts, he sets out to help educators and policymakers understand this innovative approach to assessment and the issues associated with its use. Written in straightforward language…

  13. Comparative Study of foF2 Measurements with IRI-2007 Model Predictions During Extended Solar Minimum

    NASA Technical Reports Server (NTRS)

    Zakharenkova, I. E.; Krankowski, A.; Bilitza, D.; Cherniak, Iu.V.; Shagimuratov, I.I.; Sieradzki, R.

    2013-01-01

    The unusually deep and extended solar minimum of cycle 2324 made it very difficult to predict the solar indices 1 or 2 years into the future. Most of the predictions were proven wrong by the actual observed indices. IRI gets its solar, magnetic, and ionospheric indices from an indices file that is updated twice a year. In recent years, due to the unusual solar minimum, predictions had to be corrected downward with every new indices update. In this paper we analyse how much the uncertainties in the predictability of solar activity indices affect the IRI outcome and how the IRI values calculated with predicted and observed indices compared to the actual measurements.Monthly median values of F2 layer critical frequency (foF2) derived from the ionosonde measurements at the mid-latitude ionospheric station Juliusruh were compared with the International Reference Ionosphere (IRI-2007) model predictions. The analysis found that IRIprovides reliable results that compare well with actual measurements, when the definite (observed and adjusted) indices of solar activityare used, while IRI values based on earlier predictions of these indices noticeably overestimated the measurements during the solar minimum.One of the principal objectives of this paper is to direct attention of IRI users to update their solar activity indices files regularly.Use of an older index file can lead to serious IRI overestimations of F-region electron density during the recent extended solar minimum.

  14. Optimal Clinical Time for Reliable Measurement of Transcutaneous CO2 with Ear Probes: Counterbalancing Overshoot and the Vasodilatation Effect

    PubMed Central

    Domingo, Christian; Canturri, Elisa; Moreno, Amalia; Espuelas, Humildad; Vigil, Laura; Luján, Manel

    2010-01-01

    OBJECTIVES: To determine the optimal clinical reading time for the transcutaneous measurement of oxygen saturation (SpO2) and transcutaneous CO2 (TcPCO2) in awake spontaneously breathing individuals, considering the overshoot phenomenon (transient overestimation of arterial PaCO2). EXPERIMENTAL SECTION: Observational study of 91 (75 men) individuals undergoing forced spirometry, measurement of SpO2 and TcPCO2 with the SenTec monitor every two minutes until minute 20 and arterial blood gas (ABG) analysis. Overshoot severity: (a) mild (0.1–1.9 mm Hg); (b) moderate (2–4.9 mm Hg); (c) severe: (>5 mm Hg). The mean difference was calculated for SpO2 and TcPCO2 and arterial values of PaCO2 and SpO2. The intraclass correlation coefficient (ICC) between monitor readings and blood values was calculated as a measure of agreement. RESULTS: The mean age was 63.1 ± 11.8 years. Spirometric values: FVC: 75.4 ± 6.2%; FEV1: 72.9 ± 23.9%; FEV1/FVC: 70 ± 15.5%. ABG: PaO2: 82.6 ± 13.2; PaCO2: 39.9.1 ± 4.8 mmHg; SaO2: 95.3 ± 4.4%. Overshoot analysis: overshoot was mild in 33 (36.3%) patients, moderate in 20 (22%) and severe in nine (10%); no overshoot was observed in 29 (31%) patients. The lowest mean differences between arterial blood gas and TcPCO2 was −0.57 mmHg at minute 10, although the highest ICC was obtained at minutes 12 and 14 (>0.8). The overshoot lost its influence after minute 12. For SpO2, measurements were reliable at minute 2. CONCLUSIONS: The optimal clinical reading measurement recommended for the ear lobe TcPCO2 measurement ranges between minute 12 and 14. The SpO2 measurement can be performed at minute 2. PMID:22315552

  15. A Research on Performance Measurement Based on Economic Valued-Added Comprehensive Scorecard

    NASA Astrophysics Data System (ADS)

    Chen, Qin; Zhang, Xiaomei

    With the development of economic, the traditional performance mainly rely on financial indicators could not satisfy the need of work. In order to make the performance measurement taking the best services for business goals, this paper proposed Economic Valued-Added Comprehensive Scorecard based on research of shortages and advantages of EVA and BSC .We used Analytic Hierarchy Process to build matrix to solve the weighting of EVA Comprehensive Scorecard. At last we could find the most influence factors for enterprise value forming the weighting.

  16. Should Entanglement Measures be Monogamous or Faithful?

    NASA Astrophysics Data System (ADS)

    Lancien, Cécilia; Di Martino, Sara; Huber, Marcus; Piani, Marco; Adesso, Gerardo; Winter, Andreas

    2016-08-01

    "Is entanglement monogamous?" asks the title of a popular article [B. Terhal, IBM J. Res. Dev. 48, 71 (2004)], celebrating C. H. Bennett's legacy on quantum information theory. While the answer is affirmative in the qualitative sense, the situation is less clear if monogamy is intended as a quantitative limitation on the distribution of bipartite entanglement in a multipartite system, given some particular measure of entanglement. Here, we formalize what it takes for a bipartite measure of entanglement to obey a general quantitative monogamy relation on all quantum states. We then prove that an important class of entanglement measures fail to be monogamous in this general sense of the term, with monogamy violations becoming generic with increasing dimension. In particular, we show that every additive and suitably normalized entanglement measure cannot satisfy any nontrivial general monogamy relation while at the same time faithfully capturing the geometric entanglement structure of the fully antisymmetric state in arbitrary dimension. Nevertheless, monogamy of such entanglement measures can be recovered if one allows for dimension-dependent relations, as we show explicitly with relevant examples.

  17. Health and Well-Being Metrics in Business: The Value of Integrated Reporting.

    PubMed

    Pronk, Nicolaas P; Malan, Daniel; Christie, Gillian; Hajat, Cother; Yach, Derek

    2018-01-01

    Health and well-being (HWB) are material to sustainable business performance. Yet, corporate reporting largely lacks the intentional inclusion of HWB metrics. This brief report presents an argument for inclusion of HWB metrics into existing standards for corporate reporting. A Core Scorecard and a Comprehensive Scorecard, designed by a team of subject matter experts, based on available evidence of effectiveness, and organized around the categories of Governance, Management, and Evidence of Success, may be integrated into corporate reporting efforts. Pursuit of corporate integrated reporting requires corporate governance and ethical leadership and values that ultimately align with environmental, social, and economic performance. Agreement on metrics that intentionally include HWB may allow for integrated reporting that has the potential to yield significant value for business and society alike.

  18. Development of NIST standard reference material 2373: Genomic DNA standards for HER2 measurements.

    PubMed

    He, Hua-Jun; Almeida, Jamie L; Lund, Steve P; Steffen, Carolyn R; Choquette, Steve; Cole, Kenneth D

    2016-06-01

    NIST standard reference material (SRM) 2373 was developed to improve the measurements of the HER2 gene amplification in DNA samples. SRM 2373 consists of genomic DNA extracted from five breast cancer cell lines with different amounts of amplification of the HER2 gene. The five components are derived from the human cell lines SK-BR-3, MDA-MB-231, MDA-MB-361, MDA-MB-453, and BT-474. The certified values are the ratios of the HER2 gene copy numbers to the copy numbers of selected reference genes DCK, EIF5B, RPS27A, and PMM1. The ratios were measured using quantitative polymerase chain reaction and digital PCR, methods that gave similar ratios. The five components of SRM 2373 have certified HER2 amplification ratios that range from 1.3 to 17.7. The stability and homogeneity of the reference materials were shown by repeated measurements over a period of several years. SRM 2373 is a well characterized genomic DNA reference material that can be used to improve the confidence of the measurements of HER2 gene copy number.

  19. Evaluation of Brain Iron Content Based on Magnetic Resonance Imaging (MRI): Comparison among Phase Value, R2* and Magnitude Signal Intensity

    PubMed Central

    Yan, Shen-Qiang; Sun, Jian-Zhong; Yan, Yu-Qing; Wang, He; Lou, Min

    2012-01-01

    Background and Purpose Several magnetic resonance imaging (MRI) techniques are being exploited to measure brain iron levels increasingly as iron deposition has been implicated in some neurodegenerative diseases. However, there remains no unified evaluation of these methods as postmortem measurement isn't commonly available as the reference standard. The purpose of this study was to make a comparison among these methods and try to find a new index of brain iron. Methods We measured both phase values and R2* in twenty-four adults, and performed correlation analysis among the two methods and the previously published iron concentrations. We also proposed a new method using magnitude signal intensity and compared it with R2* and brain iron. Results We found phase value correlated with R2* in substantia nigra (r = −0.723, p<0.001) and putamen (r = −0.514, p = 0.010), while no correlations in red nucleus (r = −0.236, p = 0.268) and globus pallidus (r = −0.111, p = 0.605). And the new magnitude method had significant correlations in red nucleus (r = −0.593, p = 0.002), substantia nigra (r = −0.521, p = 0.009), globus pallidus (r = −0.750, p<0.001) and putamen (r = −0.547, p = 0.006) with R2*. A strong inverse correlation was also found between the new magnitude method and previously published iron concentrations in seven brain regions (r = −0.982, P<0.001). Conclusions Our study indicates that phase value may not be used for assessing the iron content in some brain regions especially globus pallidus. The new magnitude method is highly consistent with R2* especially in globus pallidus, and we assume that this approach may be acceptable as an index of iron content in iron-rich brain regions. PMID:22363719

  20. Measurements of Lifetimes and f-Values In Highly-Charged Ions

    NASA Astrophysics Data System (ADS)

    Smith, Steven; Chutjian, Ara; Hossain, Sabbir

    2006-05-01

    Measurements have been made of lifetimes of metastable levels of highly-charged ions (HCI). These contribute to the optical absorption, emission and energy balance in the ISM, stellar and solar atmospheres, etc. The experimental lifetime measurements are carried out using the 14.0 GHz electron cyclotron ion source at the JPL facility.[l] Ions are injected into a Kingdon ion trap and stored for times longer than the metastable lifetimes. Decay channels include inter-combination, E2, M1 and 2E transitions. The UV photons are filtered by an interference filter and detected by a UV grade photomultiplier tube using a UV grade optical system. The Kingdon trap was constructed in collaboration with Texas A and M University [2]. We previously have reported lifetimes for transitions of C^+ [1]and 0^2+ [4]. Additional metastable lifetimes have been measured for M^6+, Fe^9+, Fe^10+ and Fe^13+ metastable states [5]. New results for Fe^11+ will be presented. Sabbir Hossain acknowledges support through NASA-NRC program. This work was carried out at the Jet Propulsion Laboratory/Caltech and was supported by the NASA [1] Steven J. Smith, A. Chutjian, J.B. Greenwood, Phys. Rev. A 60, 3569 (1999). [2] L.Yang and D.A. Church, Phys. Rev. Lett. 70, 3860 (1993).[3] S.J. Smith, I. Cadez, A. Chutjian, and M. Niimura, Ap. J. 602, 1075 (2004).[5] S.J. Smith , A. Chutjian, J. Lozano, Phys Rev. A 72, 062504 (2005).

  1. MEthods of ASsessing blood pressUre: identifying thReshold and target valuEs (MeasureBP): a review & study protocol.

    PubMed

    Blom, Kimberly C; Farina, Sasha; Gomez, Yessica-Haydee; Campbell, Norm R C; Hemmelgarn, Brenda R; Cloutier, Lyne; McKay, Donald W; Dawes, Martin; Tobe, Sheldon W; Bolli, Peter; Gelfer, Mark; McLean, Donna; Bartlett, Gillian; Joseph, Lawrence; Featherstone, Robin; Schiffrin, Ernesto L; Daskalopoulou, Stella S

    2015-04-01

    Despite progress in automated blood pressure measurement (BPM) technology, there is limited research linking hard outcomes to automated office BPM (OBPM) treatment targets and thresholds. Equivalences for automated BPM devices have been estimated from approximations of standardized manual measurements of 140/90 mmHg. Until outcome-driven targets and thresholds become available for automated measurement methods, deriving evidence-based equivalences between automated methods and standardized manual OBPM is the next best solution. The MeasureBP study group was initiated by the Canadian Hypertension Education Program to close this critical knowledge gap. MeasureBP aims to define evidence-based equivalent values between standardized manual OBPM and automated BPM methods by synthesizing available evidence using a systematic review and individual subject-level data meta-analyses. This manuscript provides a review of the literature and MeasureBP study protocol. These results will lay the evidenced-based foundation to resolve uncertainties within blood pressure guidelines which, in turn, will improve the management of hypertension.

  2. Electrode effects in dielectric spectroscopy measurements on (Nb +In) co-doped TiO2

    NASA Astrophysics Data System (ADS)

    Crandles, David; Yee, Susan; Savinov, Maxim; Nuzhnyy, Dimitri; Petzelt, Jan; Kamba, Stanislav; Prokes, Jan

    Recently, several papers reported the discovery of giant permittivity and low dielectric loss in (Nb+In) co-doped TiO2. A series of tests was performed which included the measurement of the frequency dependence of the dielectric permittivity and ac conductivity of co-doped (Nb+In)TiO2 as a function of electrode type, sample thickness and temperature. The data suggest that the measurements are strongly affected by the electrodes. The consistency between four contact van der Pauw dc conductivity measurements and bulk conductivity values extracted from two contact ac conductivity measurements suggest that the values of colossal permittivity are, at least in part, a result of Schottky barrier depletion widths that depend on electrode type and temperature. Nserc, Czech Science Foundation (Project 15-08389S).

  3. Serum anti-PLA2R antibody as a diagnostic biomarker of idiopathic membranous nephropathy: The optimal cut-off value for Chinese patients.

    PubMed

    Liu, Yipeng; Li, Xuan; Ma, Chaoqun; Wang, Ping; Liu, Ju; Su, Hong; Zhuo, Hao; Kong, Xianglei; Xu, Dayu; Xu, Dongmei

    2018-01-01

    The M-type phospholipase A2 receptor (PLA2R) is a specific target autoantigen identified in idiopathic membranous nephropathy (IMN). The autoantibody against PLA2R (anti-PLA2R) may be used to diagnose IMN. However, the appropriate diagnosis cut-off value for Chinese patients with IMN has not been established. In total, 119 patients who underwent renal biopsy (57 patients with IMN and 62 patients with non-IMN glomerulonephritis) and 22 healthy individuals were recruited for our observation study from Qianfoshan Hospital between September 2011 and March 2016. The serum concentration of anti-PLA2R was measured using a quantitative enzyme-linked immunosorbent assay (ELISA). The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and receiver operating characteristic (ROC) curve of anti-PLA2R in diagnosing IMN were analysed based on the ELISA detection. The sensitivity, specificity, PPV, and NPV of anti-PLA2R in the diagnosis of IMN in the Chinese patients were 82.5, 75, 69.1, and 86.3% for the 2RU/ml cut-off value; 78.9, 91.7, 86.5, and 86.5% for the 2.6RU/ml cut-off value; 59.6, 95.2, 89.5, and 77.7% for the 14RU/ml cut-off value; 50.9, 96.4, 90.6, and 74.3% for the 20RU/ml cut-off value; and 47.4, 97.6, 93.1, and 73.2% for the 40RU/ml cut-off value, respectively. The area under the ROC curve was 0.879. The cut-off value of 2.6RU/ml is recommended for the use of anti-PLA2R for the diagnosis of IMN in Chinese patients based on the ELISA. Copyright © 2017. Published by Elsevier B.V.

  4. Measuring What People Value: A Comparison of “Attitude” and “Preference” Surveys

    PubMed Central

    Phillips, Kathryn A; Johnson, F Reed; Maddala, Tara

    2002-01-01

    Objective To compare and contrast methods and findings from two approaches to valuation used in the same survey: measurement of “attitudes” using simple rankings and ratings versus measurement of “preferences” using conjoint analysis. Conjoint analysis, a stated preference method, involves comparing scenarios composed of attribute descriptions by ranking, rating, or choosing scenarios. We explore possible explanations for our findings using focus groups conducted after the quantitative survey. Methods A self-administered survey, measuring attitudes and preferences for HIV tests, was conducted at HIV testing sites in San Francisco in 1999–2000 (n = 365, response rate=96 percent). Attitudes were measured and analyzed using standard approaches. Conjoint analysis scenarios were developed using a fractional factorial design and results analyzed using random effects probit models. We examined how the results using the two approaches were both similar and different. Results We found that “attitudes” and “preferences” were generally consistent, but there were some important differences. Although rankings based on the attitude and conjoint analysis surveys were similar, closer examination revealed important differences in how respondents valued price and attributes with “halo” effects, variation in how attribute levels were valued, and apparent differences in decision-making processes. Conclusions To our knowledge, this is the first study to compare attitude surveys and conjoint analysis surveys and to explore the meaning of the results using post-hoc focus groups. Although the overall findings for attitudes and preferences were similar, the two approaches resulted in some different conclusions. Health researchers should consider the advantages and limitations of both methods when determining how to measure what people value. PMID:12546291

  5. New method of measuring low values of dielectric loss in the near millimetre wavelength region using untuned cavities

    NASA Astrophysics Data System (ADS)

    Llewellyn-Jones, D. T.; Knight, R. J.; Moffat, P. H.; Gebbie, H. A.

    1980-11-01

    In the near millimeter-wavelength region, low values of dielectric loss in a material can be readily measured by inserting a sample into an untuned cavity resonator. The high-Q values of the cavities give the technique great sensitivity to low values of loss tangent and, in contrast to other techniques, place very few restrictions on the shape, size, and position of the sample. The technique is demonstrated by measurements at 156 GHz on several polymer materials whose low loss factors are of practical interest. It is shown that the loading of an untuned cavity by a solid sample of low loss is proportional to its absorption cross section, which is the product of its volume and its linear absorption coefficient in the trivial case of n = 1. In the usual case of n greater than 1, reflection at the boundaries will affect the measured cross section in a way that has been investigated experimentally for a number of shapes, both simple and complex, and theoretically for the specific cases of slabs and cubes.

  6. A comparison between probability and information measures of uncertainty in a simulated soil map and the economic value of imperfect soil information.

    NASA Astrophysics Data System (ADS)

    Lark, R. Murray

    2014-05-01

    Conventionally the uncertainty of a conventional soil map has been expressed in terms of the mean purity of its map units: the probability that the soil profile class examined at a site would be found to correspond to the eponymous class of the simple map unit that is delineated there (Burrough et al, 1971). This measure of uncertainty has an intuitive meaning and is used for quality control in soil survey contracts (Western, 1978). However, it may be of limited value to the manager or policy maker who wants to decide whether the map provides a basis for decision making, and whether the cost of producing a better map would be justified. In this study I extend a published analysis of the economic implications of uncertainty in a soil map (Giasson et al., 2000). A decision analysis was developed to assess the economic value of imperfect soil map information for agricultural land use planning. Random error matrices for the soil map units were then generated, subject to constraints which ensure consistency with fixed frequencies of the different soil classes. For each error matrix the mean map unit purity was computed, and the value of the implied imperfect soil information was computed by the decision analysis. An alternative measure of the uncertainty in a soil map was considered. This is the mean soil map information which is the difference between the information content of a soil observation, at a random location in the region, and the information content of a soil observation given that the map unit is known. I examined the relationship between the value of imperfect soil information and the purity and information measures of map uncertainty. In both cases there was considerable variation in the economic value of possible maps with fixed values of the uncertainty measure. However, the correlation was somewhat stronger with the information measure, and there was a clear upper bound on the value of an imperfect soil map when the mean information takes some

  7. Measuring Resident Well-Being: Impostorism and Burnout Syndrome in Residency

    PubMed Central

    Legassie, Jenny; Zibrowski, Elaine M.

    2008-01-01

    Background Assessing resident well-being is becoming increasingly important from a programmatic standpoint. Two measures that have been used to assess this are the Clance Impostor Scale (CIS) and the Maslach Burnout Inventory-Human Services Survey (MBI-HSS). However, little is known about the relationship between the two phenomena. Objectives To explore the prevalence and association between impostorism and burnout syndrome in a sample of internal medicine residents. Design Anonymous, cross-sectional postal survey. Participants Forty-eight internal medicine residents (postgraduate year [PGY] 1–3) at the Schulich School of Medicine & Dentistry (62.3% response rate). Measurements and Main Results Short demographic questionnaire, CIS and MBI-HSS. Impostorism and burnout syndrome were identified in 43.8% and 12.5% of residents, respectively. With the exception of a negative correlation between CIS scores and the MBI’s personal accomplishment subscale (r = −.30; 95% CI −.54 to −.02), no other significant relations were identified. Foreign-trained residents were more likely to score as impostors (odds ratio [OR] 10.7; 95% CI 1.2 to 98.2) while senior residents were more likely to experience burnout syndrome (OR 16.5 95% CI 1.6 to 168.5). Conclusions Both impostorism and burnout syndrome appear to be threats to resident well-being in our program. The lack of relationship between the two would suggest that programs and researchers wishing to address the issue of resident distress should consider using both measures. The finding that foreign-trained residents appear to be more susceptible to impostorism warrants further study. PMID:18612750

  8. United States Population-Based Estimates of Patient-Reported Outcomes Measurement Information System Symptom and Functional Status Reference Values for Individuals With Cancer.

    PubMed

    Jensen, Roxanne E; Potosky, Arnold L; Moinpour, Carol M; Lobo, Tania; Cella, David; Hahn, Elizabeth A; Thissen, David; Smith, Ashley Wilder; Ahn, Jaeil; Luta, George; Reeve, Bryce B

    2017-06-10

    Purpose To estimate cancer population-based reference values in the United States for eight PROMIS (Patient-Reported Outcomes Measurement Information System) domains by age and stage of disease. Patients and Methods For the Measuring Your Health (MY-Health) study, persons newly diagnosed with cancer (prostate, colorectal, non-small-cell lung, non-Hodgkin lymphoma, breast, uterine, or cervical) from 2010 to 2012 (N = 5,284) were recruited through the National Cancer Institute's SEER Program. Participants were mailed surveys 6 to 13 months after diagnosis. Raking by race/ethnicity, age, and stage generated weighted average PROMIS scores for pain interference, fatigue, anxiety, depression, sleep disturbance, physical function, ability to participate in social roles, and cognitive function. PROMIS measures are standardized to a T-score metric, with a score of 50 representing the general US population mean. Clinically meaningful differences were defined as a 3-point difference in scores. Results Several reference values (means) for patients with cancer were worse than the general United States population norms of 50. These include pain interference (52.4), fatigue (52.2), and physical function (44.1). Reference values were highest (ie, showed greatest symptom burden) in lung cancer (pain interference, 55.5; fatigue, 57.3; depression, 51.4) and cervical cancer (anxiety, 53.2; sleep disturbance, 53.4). Reference values for patients age 65 to 84 years reported lower sleep disturbance, anxiety, and depression, and better cognitive function than younger patients. Cancer reference values were poorer among those with advanced disease compared with patients with limited or no evidence of disease, specifically physical function (41.1 v 46.6, respectively), fatigue (55.8 v 50.2, respectively), and pain interference (55.2 v 50.9, respectively). Conclusion In a large, population-based sample of patients with recently diagnosed cancer, we observed symptom severity and functional

  9. Double-Pulsed 2-Micrometer Lidar Validation for Atmospheric CO2 Measurements

    NASA Technical Reports Server (NTRS)

    Singh, Upendra N.; Refaat, Tamer F.; Yu, Jirong; Petros, Mulugeta; Remus, Ruben

    2015-01-01

    A double-pulsed, 2-micron Integrated Path Differential Absorption (IPDA) lidar instrument for atmospheric carbon dioxide (CO2) measurements is successfully developed at NASA Langley Research Center (LaRC). Based on direct detection technique, the instrument can be operated on ground or onboard a small aircraft. Key features of this compact, rugged and reliable IPDA lidar includes high transmitted laser energy, wavelength tuning, switching and locking, and sensitive detection. As a proof of concept, the IPDA ground and airborne CO2 measurement and validation will be presented. IPDA lidar CO2 measurements ground validation were conducted at NASA LaRC using hard targets and a calibrated in-situ sensor. Airborne validation, conducted onboard the NASA B-200 aircraft, included CO2 plum detection from power stations incinerators, comparison to in-flight CO2 in-situ sensor and comparison to air sampling at different altitude conducted by NOAA at the same site. Airborne measurements, spanning for 20 hours, were obtained from different target conditions. Ground targets included soil, vegetation, sand, snow and ocean. In addition, cloud slicing was examined over the ocean. These flight validations were conducted at different altitudes, up to 7 km, with different wavelength controlled weighing functions. CO2 measurement results agree with modeling conducted through the different sensors, as will be discussed.

  10. Enhanced collectivity in 12Be

    NASA Astrophysics Data System (ADS)

    Morse, C.; McCutchan, E. A.; Iwasaki, H.; Lister, C. J.; Bader, V. M.; Bazin, D.; Beceiro Novo, S.; Chowdhury, P.; Gade, A.; Johnson, T. D.; Loelius, C.; Lunderberg, E.; Merchan, E.; Prasher, V. S.; Recchia, F.; Sonzogni, A. A.; Weisshaar, D.; Whitmore, K.

    2018-05-01

    Electromagnetic quadrupole transition strength is a sensitive probe of the evolution of the structure of nuclei, particularly the competition between collectivity and magicity. We have performed a new lifetime measurement of the 21+ state of 12Be to study the interplay of these phenomena. The lifetime was measured with the Doppler Shift Attenuation Method using the γ-ray detector GRETINA. Excited states of 12Be were produced via inelastic scattering at 55 MeV/nucleon, using several different targets to control for systematic uncertainties in the stopping powers. The lifetime is determined to be τ = 1.38 ± 0.10(stat) ± 0.19(sys) ps, which is about half the previously reported value at twice the precision. The reduced transition strength deduced from this result is B (E 2 ;21+ → 01+) = 14.2 ± 1.0(stat) ± 2.0(sys) e2fm4, which supports the quenching of the N = 8 shell gap in 12Be.

  11. Measurement of the proton structure function F 2 from the 1993 HERA data

    NASA Astrophysics Data System (ADS)

    Derrick, M.; Krakauer, D.; Magill, S.; Musgrave, B.; Repond, J.; Schlereth, J.; Stanek, R.; Talaga, R. L.; Thron, J.; Arzarello, F.; Ayad, R.; Bari, G.; Basile, M.; Bellagamba, L.; Boscherini, D.; Bruni, A.; Bruni, G.; Bruni, P.; Cara Romeo, G.; Castellini, G.; Chiarini, M.; Cifarelli, L.; Cindolo, F.; Ciralli, F.; Contin, A.; D'Auria, S.; Frasconi, F.; Giusti, P.; Iacobucci, G.; Laurenti, G.; Levi, G.; Margotti, A.; Massam, T.; Nania, R.; Nemoz, C.; Palmonari, F.; Polini, A.; Sartorelli, G.; Timellini, R.; Zamora Garcia, Y.; Zichichi, A.; Bargende, A.; Crittenden, J.; Desch, K.; Diekmann, B.; Doeker, T.; Feld, L.; Frey, A.; Geerts, M.; Geitz, G.; Grothe, M.; Hartmann, H.; Haun, D.; Heinloth, K.; Hilger, E.; Jakob, H.-P.; Katz, U. F.; Mari, S. M.; Mass, A.; Mengel, S.; Mollen, J.; Paul, E.; Rembser, Ch.; Schattevoy, R.; Schneider, J.-L.; Schramm, D.; Stamm, J.; Wedemeyer, R.; Campbell-Robson, S.; Cassidy, A.; Dyce, N.; Foster, B.; George, S.; Gilmore, R.; Heath, G. P.; Heath, H. F.; Llewellyn, T. J.; Morgado, C. J. S.; Norman, D. J. P.; O'Mara, J. A.; Tapper, R. J.; Wilson, S. S.; Yoshida, R.; Rau, R. R.; Arneodo, M.; Iannotti, L.; Schioppa, M.; Susinno, G.; Bernstein, A.; Caldwell, A.; Gialas, I.; Parsons, J. A.; Ritz, S.; Sciulli, F.; Straub, P. B.; Wai, L.; Yang, S.; Borzemski, P.; Chwastowski, J.; Eskreys, A.; Piotrzkowski, K.; Zachara, M.; Zawiejski, L.; Adamczyk, L.; Bednarek, B.; Eskreys, K.; Jeleń, K.; Kisielewska, D.; Kowalski, T.; Rulikowska-Zarębska, E.; Suszycki, L.; Zając, J.; Kędzierski, T.; Kotański, A.; Przybycień, M.; Bauerdick, L. A. T.; Behrens, U.; Bienlein, J. K.; Böttcher, S.; Coldewey, C.; Drews, G.; Flasiński, M.; Gilkinson, D. J.; Göttlicher, P.; Gutjahr, B.; Haas, T.; Hagge, L.; Hain, W.; Hasell, D.; Heßling, H.; Hultschig, H.; Iga, Y.; Joos, P.; Kasemann, M.; Klanner, R.; Koch, W.; Köpke, L.; Kötz, U.; Kowalski, H.; Kröger, W.; Krüger, J.; Labs, J.; Ladage, A.; Löhr, B.; Löwe, M.; Lüke, D.; Mainusch, J.; Mańczak, O.; Ng, J. S. T.; Nickel, S.; Notz, D.; Ohrenberg, K.; Roco, M.; Rohde, M.; Roldán, J.; Schneekloth, U.; Schulz, W.; Selonke, F.; Stiliaris, E.; Voß, T.; Westphal, D.; Wolf, G.; Youngman, C.; Grabosch, H. J.; Leich, A.; Meyer, A.; Rethfeldt, C.; Schlenstedt, S.; Barbagli, G.; Pelfer, P.; Anzivino, G.; Maccarrone, G.; de Pasquale, S.; Qian, S.; Votano, L.; Bamberger, A.; Freidhof, A.; Poser, T.; Söldner-Rembold, S.; Schroeder, J.; Theisen, G.; Trefzger, T.; Brook, N. H.; Bussey, P. J.; Doyle, A. T.; Fleck, I.; Jamieson, V. A.; Saxon, D. H.; Utley, M. L.; Wilson, A. S.; Dannemann, A.; Holm, U.; Horstmann, D.; Kammerlocher, H.; Krebs, B.; Neumann, T.; Sinkus, R.; Wick, K.; Badura, E.; Burow, B. D.; Fürtjes, A.; Lohrmann, E.; Milewski, J.; Nakahata, M.; Pavel, N.; Poelz, G.; Schott, W.; Terron, J.; Zetsche, F.; Bacon, T. C.; Beuselinck, R.; Butterworth, I.; Gallo, E.; Harris, V. L.; Hung, B. H.; Long, K. R.; Miller, D. B.; Morawitz, P. P. O.; Prinias, A.; Sedgbeer, J. K.; Whitfield, A. F.; Mallik, U.; McCliment, E.; Wang, M. Z.; Zhang, Y.; Cloth, P.; Filges, D.; An, S. H.; Hong, S. M.; Nam, S. W.; Park, S. K.; Suh, M. H.; Yon, S. H.; Imlay, R.; Kartik, S.; Kim, H.-J.; McNeil, R. R.; Metcalf, W.; Nadendla, V. K.; Barreiro, F.; Cases, G.; Graciani, R.; Hernández, J. M.; Hervás, L.; Labarga, L.; Del Peso, J.; Puga, J.; de Trocóniz, J. F.; Ikraiam, F.; Mayer, J. K.; Smith, G. R.; Corriveau, F.; Hanna, D. S.; Hartmann, J.; Hung, L. W.; Lim, J. N.; Matthews, C. G.; Mitchell, J. W.; Patel, P. M.; Sinclair, L. E.; Stairs, D. G.; St. Laurent, M.; Ullmann, R.; Bashkirov, V.; Dolgoshein, B. A.; Stifutkin, A.; Bashindzhagyan, G. L.; Ermolov, P. F.; Gladilin, L. K.; Golubkov, Y. A.; Kobrin, V. D.; Kuzmin, V. A.; Proskuryakov, A. S.; Savin, A. A.; Shcheglova, L. M.; Solomin, A. N.; Zotov, N. P.; Bentvelsen, S.; Botje, M.; Chlebana, F.; Dake, A.; Engelen, J.; de Jong, P.; de Kamps, M.; Kooijman, P.; Kruse, A.; O'Dell, V.; Tenner, A.; Tiecke, H.; Verkerke, W.; Vreeswijk, M.; Wiggers, L.; de Wolf, E.; van Woudenberg, R.; Acosta, D.; Bylsma, B.; Durkin, L. S.; Honscheid, K.; Li, C.; Ling, T. Y.; McLean, K. W.; Murray, W. N.; Park, I. H.; Romanowski, T. A.; Seidlein, R.; Bailey, D. S.; Blair, G. A.; Byrne, A.; Cashmore, R. J.; Cooper-Sarkar, A. M.; Daniels, D.; Devenish, R. C. E.; Harnew, N.; Lancaster, M.; Luffman, P. E.; Lindemann, L.; McFall, J.; Nath, C.; Quadt, A.; Uijterwaal, H.; Walczak, R.; Wilson, F. F.; Yip, T.; Abbiendi, G.; Bertolin, A.; Brugnera, R.; Carlin, R.; Dal Corso, F.; de Giorgi, M.; Dosselli, U.; Gasparini, F.; Limentani, S.; Morandin, M.; Posocco, M.; Stanco, L.; Stroili, R.; Voci, C.; Bulmahn, J.; Butterworth, J. M.; Feild, R. G.; Oh, B. Y.; Whitmore, J. J.; D'Agostini, G.; Iori, M.; Marini, G.; Mattioli, M.; Nigro, A.; Tassi, E.; Hart, J. C.; McCubbin, N. A.; Prytz, K.; Shah, T. P.; Short, T. L.; Barberis, E.; Cartiglia, N.; Dubbs, T.; Heusch, C.; van Hook, M.; Hubbard, B.; Lockman, W.; Rahn, J. T.; Sadrozinski, H. F.-W.; Seiden, A.; Biltzinger, J.; Seifert, R. J.; Walenta, A. H.; Zech, G.; Abramowicz, H.; Briskin, G.; Dagan, S.; Levy, A.; Hasegawa, T.; Hazumi, M.; Ishii, T.; Kuze, M.; Mine, S.; Nagasawa, Y.; Nagira, T.; Nakao, M.; Suzuki, I.; Tokushuku, K.; Yamada, S.; Yamazaki, Y.; Chiba, M.; Hamatsu, R.; Hirose, T.; Homma, K.; Kitamura, S.; Nagayama, S.; Nakamitsu, Y.; Cirio, R.; Costa, M.; Ferrero, M. I.; Lamberti, L.; Maselli, S.; Peroni, C.; Sacchi, R.; Solano, A.; Staiano, A.; Dardo, M.; Bandyopadhyay, D.; Benard, F.; Brkic, M.; Crombie, M. B.; Gingrich, D. M.; Hartner, G. F.; Joo, K. K.; Levman, G. M.; Martin, J. F.; Orr, R. S.; Sampson, C. R.; Teuscher, R. J.; Catterall, C. D.; Jones, T. W.; Kaziewicz, P. B.; Lane, J. B.; Saunders, R. L.; Shulman, J.; Blankenship, K.; Kochocki, J.; Lu, B.; Mo, L. W.; Bogusz, W.; Charchula, K.; Ciborowski, J.; Gajewski, J.; Grzelak, G.; Kasprzak, M.; Krzyżanowski, M.; Muchorowski, K.; Nowak, R. J.; Pawlak, J. M.; Tymieniecka, T.; Wróblewski, A. K.; Zakrzewski, J. A.; Żarnecki, A. F.; Adamus, M.; Eisenberg, Y.; Glasman, C.; Karshon, U.; Revel, D.; Shapira, A.; Ali, I.; Behrens, B.; Dasu, S.; Fordham, C.; Foudas, C.; Goussiou, A.; Loveless, R. J.; Reeder, D. D.; Silverstein, S.; Smith, W. H.; Tsurugai, T.; Bhadra, S.; Frisken, W. R.; Furutani, K. M.

    1995-09-01

    The ZEUS detector has been used to measure the proton structure function F 2. During 1993 HERA collided 26.7 GeV electrons on 820 GeV protons. The data sample corresponds to an integrated luminosity of 0.54 pb-1, representing a twenty fold increase in statistics compared to that of 1992. Results are presented for 7< Q 2<104 GeV2 and x values as low as 3×10-4. The rapid rise in F 2 as x decreases observed previously is now studied in greater detail and persists for Q 2 values up to 500 GeV2.

  12. The four principles: Can they be measured and do they predict ethical decision making?

    PubMed Central

    2012-01-01

    Background The four principles of Beauchamp and Childress - autonomy, non-maleficence, beneficence and justice - have been extremely influential in the field of medical ethics, and are fundamental for understanding the current approach to ethical assessment in health care. This study tests whether these principles can be quantitatively measured on an individual level, and then subsequently if they are used in the decision making process when individuals are faced with ethical dilemmas. Methods The Analytic Hierarchy Process was used as a tool for the measurement of the principles. Four scenarios, which involved conflicts between the medical ethical principles, were presented to participants who then made judgments about the ethicality of the action in the scenario, and their intentions to act in the same manner if they were in the situation. Results Individual preferences for these medical ethical principles can be measured using the Analytic Hierarchy Process. This technique provides a useful tool in which to highlight individual medical ethical values. On average, individuals have a significant preference for non-maleficence over the other principles, however, and perhaps counter-intuitively, this preference does not seem to relate to applied ethical judgements in specific ethical dilemmas. Conclusions People state they value these medical ethical principles but they do not actually seem to use them directly in the decision making process. The reasons for this are explained through the lack of a behavioural model to account for the relevant situational factors not captured by the principles. The limitations of the principles in predicting ethical decision making are discussed. PMID:22606995

  13. The four principles: can they be measured and do they predict ethical decision making?

    PubMed

    Page, Katie

    2012-05-20

    The four principles of Beauchamp and Childress--autonomy, non-maleficence, beneficence and justice--have been extremely influential in the field of medical ethics, and are fundamental for understanding the current approach to ethical assessment in health care. This study tests whether these principles can be quantitatively measured on an individual level, and then subsequently if they are used in the decision making process when individuals are faced with ethical dilemmas. The Analytic Hierarchy Process was used as a tool for the measurement of the principles. Four scenarios, which involved conflicts between the medical ethical principles, were presented to participants who then made judgments about the ethicality of the action in the scenario, and their intentions to act in the same manner if they were in the situation. Individual preferences for these medical ethical principles can be measured using the Analytic Hierarchy Process. This technique provides a useful tool in which to highlight individual medical ethical values. On average, individuals have a significant preference for non-maleficence over the other principles, however, and perhaps counter-intuitively, this preference does not seem to relate to applied ethical judgements in specific ethical dilemmas. People state they value these medical ethical principles but they do not actually seem to use them directly in the decision making process. The reasons for this are explained through the lack of a behavioural model to account for the relevant situational factors not captured by the principles. The limitations of the principles in predicting ethical decision making are discussed.

  14. Experimental scheme for qubit and qutrit symmetric informationally complete positive operator-valued measurements using multiport devices

    NASA Astrophysics Data System (ADS)

    Tabia, Gelo Noel M.

    2012-12-01

    It is crucial for various quantum information processing tasks that the state of a quantum system can be determined reliably and efficiently from general quantum measurements. One important class of measurements for this purpose is symmetric informationally complete positive operator-valued measurements (SIC-POVMs). SIC-POVMs have the advantage of providing an unbiased estimator for the quantum state with the minimal number of outcomes needed for full tomography. By virtue of Naimark's dilation theorem, any POVM can always be realized with a suitable coupling between the system and an auxiliary system and by performing a projective measurement on the joint system. In practice, finding the appropriate coupling is rather nontrivial. Here we propose an experimental design for directly implementing SIC-POVMs using multiport devices and path-encoded qubits and qutrits, the utility of which has recently been demonstrated by several experimental groups around the world. Furthermore, we describe how these multiports can be attained in practice with an integrated photonic system composed of nested linear optical elements.

  15. Measurements of tropospheric NO2 in Romania using a zenith-sky mobile DOAS system and comparisons with satellite observations.

    PubMed

    Constantin, Daniel-Eduard; Merlaud, Alexis; Van Roozendael, Michel; Voiculescu, Mirela; Fayt, Caroline; Hendrick, François; Pinardi, Gaia; Georgescu, Lucian

    2013-03-20

    In this paper we present a new method for retrieving tropospheric NO2 Vertical Column Density (VCD) from zenith-sky Differential Optical Absorption Spectroscopy (DOAS) measurements using mobile observations. This method was used during three days in the summer of 2011 in Romania, being to our knowledge the first mobile DOAS measurements peformed in this country. The measurements were carried out over large and different areas using a mobile DOAS system installed in a car. We present here a step-by-step retrieval of tropospheric VCD using complementary observations from ground and space which take into account the stratospheric contribution, which is a step forward compared to other similar studies. The detailed error budget indicates that the typical uncertainty on the retrieved NO2tropospheric VCD is less than 25%. The resulting ground-based data set is compared to satellite measurements from the Ozone Monitoring Instrument (OMI) and the Global Ozone Monitoring Experiment-2 (GOME-2). For instance, on 18 July 2011, in an industrial area located at 47.03°N, 22.45°E, GOME-2 observes a tropospheric VCD value of (3.4 ± 1.9) × 1015 molec./cm2, while average mobile measurements in the same area give a value of (3.4 ± 0.7) × 10(15) molec./cm2. On 22 August 2011, around Ploiesti city (44.99°N, 26.1°E), the tropospheric VCD observed by satellites is (3.3 ± 1.9) × 10(15) molec./cm2 (GOME-2) and (3.2 ± 3.2) × 10(15) molec./cm2 (OMI), while average mobile measurements give (3.8 ± 0.8) × 10(15) molec./cm2. Average ground measurements over "clean areas", on 18 July 2011, give (2.5 ± 0.6) × 10(15) molec./cm2 while the satellite observes a value of (1.8 ± 1.3) × 10(15) molec./cm2.

  16. Measurements of Tropospheric NO2 in Romania Using a Zenith-Sky Mobile DOAS System and Comparisons with Satellite Observations

    PubMed Central

    Constantin, Daniel-Eduard; Merlaud, Alexis; Van Roozendael, Michel; Voiculescu, Mirela; Fayt, Caroline; Hendrick, François; Pinardi, Gaia; Georgescu, Lucian

    2013-01-01

    In this paper we present a new method for retrieving tropospheric NO2 Vertical Column Density (VCD) from zenith-sky Differential Optical Absorption Spectroscopy (DOAS) measurements using mobile observations. This method was used during three days in the summer of 2011 in Romania, being to our knowledge the first mobile DOAS measurements peformed in this country. The measurements were carried out over large and different areas using a mobile DOAS system installed in a car. We present here a step-by-step retrieval of tropospheric VCD using complementary observations from ground and space which take into account the stratospheric contribution, which is a step forward compared to other similar studies. The detailed error budget indicates that the typical uncertainty on the retrieved NO2tropospheric VCD is less than 25%. The resulting ground-based data set is compared to satellite measurements from the Ozone Monitoring Instrument (OMI) and the Global Ozone Monitoring Experiment-2 (GOME-2). For instance, on 18 July 2011, in an industrial area located at 47.03°N, 22.45°E, GOME-2 observes a tropospheric VCD value of (3.4 ± 1.9) × 1015 molec./cm2, while average mobile measurements in the same area give a value of (3.4 ± 0.7) × 1015 molec./cm2. On 22 August 2011, around Ploiesti city (44.99°N, 26.1°E), the tropospheric VCD observed by satellites is (3.3 ± 1.9) × 1015 molec./cm2 (GOME-2) and (3.2 ± 3.2) × 1015 molec./cm2 (OMI), while average mobile measurements give (3.8 ± 0.8) × 1015 molec./cm2. Average ground measurements over “clean areas”, on 18 July 2011, give (2.5 ± 0.6) × 1015 molec./cm2 while the satellite observes a value of (1.8 ± 1.3) × 1015 molec./cm2. PMID:23519349

  17. Measurement of susceptibility artifacts with histogram-based reference value on magnetic resonance images according to standard ASTM F2119.

    PubMed

    Heinrich, Andreas; Teichgräber, Ulf K; Güttler, Felix V

    2015-12-01

    The standard ASTM F2119 describes a test method for measuring the size of a susceptibility artifact based on the example of a passive implant. A pixel in an image is considered to be a part of an image artifact if the intensity is changed by at least 30% in the presence of a test object, compared to a reference image in which the test object is absent (reference value). The aim of this paper is to simplify and accelerate the test method using a histogram-based reference value. Four test objects were scanned parallel and perpendicular to the main magnetic field, and the largest susceptibility artifacts were measured using two methods of reference value determination (reference image-based and histogram-based reference value). The results between both methods were compared using the Mann-Whitney U-test. The difference between both reference values was 42.35 ± 23.66. The difference of artifact size was 0.64 ± 0.69 mm. The artifact sizes of both methods did not show significant differences; the p-value of the Mann-Whitney U-test was between 0.710 and 0.521. A standard-conform method for a rapid, objective, and reproducible evaluation of susceptibility artifacts could be implemented. The result of the histogram-based method does not significantly differ from the ASTM-conform method.

  18. Redetermination of clinobaryl­ite, BaBe2Si2O7

    PubMed Central

    Domizio, Adrien J. Di; Downs, Robert T.; Yang, Hexiong

    2012-01-01

    Clinobaryl­ite, ideally BaBe2Si2O7 (chemical name barium diberyllium disilicate), is a sorosilicate mineral and dimorphic with baryl­ite. It belongs to a group of compounds characterized by the general formula BaM 2+ 2Si2O7, with M 2+ = Be, Mg, Fe, Mn, Zn, Co, or Cu, among which the Be-, Fe-, and Cu-members have been found in nature. The crystal structure of clinobaryl­ite has been re-examined in this study based on single-crystal X-ray diffraction data collected from a natural sample from the type locality (Khibiny Massif, Kola Peninsula, Russia). The structure of clinobaryl­ite can be considered as a framework of BeO4 and SiO4 tetra­hedra, with one of the O atoms coordinated to two Be and one Si, one coordinated to two Si, and two O atoms coordinated to one Si and one Be atom. The BeO4 tetra­hedra share corners, forming chains parallel to the c axis, which are inter­linked by the Si2O7 units oriented parallel to the a axis. The Ba2+ cations (site symmetry m..) are in the framework channels and are coordinated by eleven O atoms in form of an irregular polyhedron. The Si—Obr (bridging O atom, at site symmetry m..) bond length, the Si—Onbr (non-bridging O atoms) bond lengths, and the Si—O—Si angle within the Si2O7 unit are in marked contrast to the corresponding values determined in the previous study [Krivovichev et al. (2004 ▶). N. Jb. Miner. Mh. pp. 373–384]. PMID:23125568

  19. On vector-valued Poincaré series of weight 2

    NASA Astrophysics Data System (ADS)

    Meneses, Claudio

    2017-10-01

    Given a pair (Γ , ρ) of a Fuchsian group of the first kind, and a unitary representation ρ of Γ of arbitrary rank, the problem of construction of vector-valued Poincaré series of weight 2 is considered. Implications in the theory of parabolic bundles are discussed. When the genus of the group is zero, it is shown how an explicit basis for the space of these functions can be constructed.

  20. Attentional Selection Can Be Predicted by Reinforcement Learning of Task-relevant Stimulus Features Weighted by Value-independent Stickiness.

    PubMed

    Balcarras, Matthew; Ardid, Salva; Kaping, Daniel; Everling, Stefan; Womelsdorf, Thilo

    2016-02-01

    Attention includes processes that evaluate stimuli relevance, select the most relevant stimulus against less relevant stimuli, and bias choice behavior toward the selected information. It is not clear how these processes interact. Here, we captured these processes in a reinforcement learning framework applied to a feature-based attention task that required macaques to learn and update the value of stimulus features while ignoring nonrelevant sensory features, locations, and action plans. We found that value-based reinforcement learning mechanisms could account for feature-based attentional selection and choice behavior but required a value-independent stickiness selection process to explain selection errors while at asymptotic behavior. By comparing different reinforcement learning schemes, we found that trial-by-trial selections were best predicted by a model that only represents expected values for the task-relevant feature dimension, with nonrelevant stimulus features and action plans having only a marginal influence on covert selections. These findings show that attentional control subprocesses can be described by (1) the reinforcement learning of feature values within a restricted feature space that excludes irrelevant feature dimensions, (2) a stochastic selection process on feature-specific value representations, and (3) value-independent stickiness toward previous feature selections akin to perseveration in the motor domain. We speculate that these three mechanisms are implemented by distinct but interacting brain circuits and that the proposed formal account of feature-based stimulus selection will be important to understand how attentional subprocesses are implemented in primate brain networks.

  1. Network analysis of surgical innovation: Measuring value and the virality of diffusion in robotic surgery.

    PubMed

    Garas, George; Cingolani, Isabella; Panzarasa, Pietro; Darzi, Ara; Athanasiou, Thanos

    2017-01-01

    Existing surgical innovation frameworks suffer from a unifying limitation, their qualitative nature. A rigorous approach to measuring surgical innovation is needed that extends beyond detecting simply publication, citation, and patent counts and instead uncovers an implementation-based value from the structure of the entire adoption cascades produced over time by diffusion processes. Based on the principles of evidence-based medicine and existing surgical regulatory frameworks, the surgical innovation funnel is described. This illustrates the different stages through which innovation in surgery typically progresses. The aim is to propose a novel and quantitative network-based framework that will permit modeling and visualizing innovation diffusion cascades in surgery and measuring virality and value of innovations. Network analysis of constructed citation networks of all articles concerned with robotic surgery (n = 13,240, Scopus®) was performed (1974-2014). The virality of each cascade was measured as was innovation value (measured by the innovation index) derived from the evidence-based stage occupied by the corresponding seed article in the surgical innovation funnel. The network-based surgical innovation metrics were also validated against real world big data (National Inpatient Sample-NIS®). Rankings of surgical innovation across specialties by cascade size and structural virality (structural depth and width) were found to correlate closely with the ranking by innovation value (Spearman's rank correlation coefficient = 0.758 (p = 0.01), 0.782 (p = 0.008), 0.624 (p = 0.05), respectively) which in turn matches the ranking based on real world big data from the NIS® (Spearman's coefficient = 0.673;p = 0.033). Network analysis offers unique new opportunities for understanding, modeling and measuring surgical innovation, and ultimately for assessing and comparing generative value between different specialties. The novel surgical innovation metrics developed may

  2. The influence of different referencing methods on the accuracy of δ(13) C value measurement of ethanol fuel by gas chromatography/combustion/isotope ratio mass spectrometry.

    PubMed

    Neves, Laura A; Rodrigues, Janaína M; Daroda, Romeu J; Silva, Paulo R M; Ferreira, Alexandre A; Aranda, Donato A G; Eberlin, Marcos N; Fasciotti, Maíra

    2015-11-15

    Brazil is the largest producer of sugar cane bioethanol in the world. Isotope ratio mass spectrometry (IRMS) is the technique of choice to certify the origin/raw materials for ethanol production, but the lack of certified reference materials (CRMs) for accurate measurements of δ(13) C values traceable to Vienna Pee Dee Belemnite (VPDB), the international zero point for (13) C/(12) C measurements, certified and compatible with gas chromatography (GC)/IRMS instruments may compromise the accuracy of δ(13) C determinations. We evaluated the influence of methods for the calibration and normalization of raw δ(13) C values of ethanol samples. Samples were analyzed by GC/C/IRMS using two different GC columns. Different substances were used as isotopic standards for the working gas calibration. The δ(13) C values obtained with the three methods of normalization were statistically compared with those obtained with elemental analyzer (EA)/IRMS, since the δ(13) C results obtained using EA are traceable to VPDB via the NBS 22 reference material. It was observed that both the isotopic reference material for CO2 calibration and the GC column have a major effect on the δ(13) C measurements, leading to a bias of almost 2-3 ‰ in the δ(13) C values. All three methods of normalization were equivalent in performance, enabling an improvement in the GC/C/IRMS accuracy, compared with the EA/IRMS reference values for the samples. All the methods of CO2 calibration, chromatography and normalization presented in this work demonstrated several sources of traceability and accuracy loss for the determination of δ(13) C values in ethanol fuel samples by GC/C/IRMS. This work has also shown the importance of using proper CRMs traceable to VPBD that should be compatible and certified using GC/C/IRMS, ideally in a wide range of δ(13) C values. This is important not only for bioethanol fuel samples, but also for many analytes commonly analyzed by IRMS. Copyright © 2015 John Wiley & Sons

  3. Lifetime measurements in shape transition nucleus 188Pt

    NASA Astrophysics Data System (ADS)

    Rohilla, Aman; Gupta, C. K.; Singh, R. P.; Muralithar, S.; Chakraborty, S.; Sharma, H. P.; Kumar, A.; Govil, I. M.; Biswas, D. C.; Chamoli, S. K.

    2017-04-01

    Nuclear level lifetimes of high spin states in yrast and non-yrast bands of 188Pt nucleus have been measured using recoil distance plunger setup present at IUAC, Delhi. In the experiment nuclear states of interest were populated via 174Yb(18O,4 n)188Pt reaction at a beam energy of 79MeV provided by 15 UD Pelletron accelerator. The extracted B(E2\\downarrow) values show an initial rise up to 4+ state and then a nearly constant behavior with spin along yrast band, indicating change of nuclear structure in 188Pt at low spins. The good agreement between experimental and TPSM model B(E2\\downarrow) values up to 4^+ state suggests an increase in axial deformation of the nucleus. The average absolute β2 = 0.20 (3) obtained from measured B(E2\\downarrow) values matches well the values predicted by CHFB and IBM calculations for oblate ( β2 ˜ -0.19) and prolate (β2 ˜ 0.22) shapes. As the lifetime measurements do not yield the sign of β2, no definite conclusion can be drawn on the prolate or oblate collectivity of 188Pt on the basis of present measurements.

  4. Comparison of endotracheal tube cuff pressure values before and after training seminar.

    PubMed

    Özcan, Ayça Tuba Dumanlı; Döğer, Cihan; But, Abdülkadir; Kutlu, Işık; Aksoy, Şemsi Mustafa

    2018-06-01

    It is recommended that endotracheal cuff (ETTc) pressure be between 20 and 30 cm H 2 O. In this present study, we intend to observe average cuff pressure values in our clinic and the change in these values after the training seminar. The cuff pressure values of 200 patients intubated following general anesthesia induction in the operating theatre were measured following intubation. One hundred patients whose values were measured before the training seminar held for all physician assistants, and 100 patients whose values were measured after the training seminar were regarded as Group 1 and Group 2, respectively. Cuff pressures of both groups were recorded, and the difference between them was shown. Moreover, cuff pressure values were explored according to the working period of the physician assistants. There was no significant difference between the groups in terms of age, gender and tube diameters. Statistically significant difference was found between cuff pressure values before and after the training (p < 0.001). Average pressure measure for Group I was 54 cm H 2 O, while average pressure in Group II declined to 33 cm H 2 O. It was observed that as the working period and experience of physician assistants increased, cuff pressure values decreased, however no statistically significant different was found (p < 0.375). We believe that clinical experience does not have significant effects on cuff pressure and that training seminars held at intervals would prevent high cuff pressure values and potential complications.

  5. On nonepistemic values in conservation biology.

    PubMed

    Baumgaertner, Bert; Holthuijzen, Wieteke

    2017-02-01

    Conservation biology is a uniquely interdisciplinary science with strong roots in ecology, but it also embraces a value-laden and mission-oriented framework. This combination of science and values causes conservation biology to be at the center of critique regarding the discipline's scientific credibility-especially the division between the realms of theory and practice. We identify this dichotomy between seemingly objective (fact-based) and subjective (value-laden) practices as the measure-value dichotomy, whereby measure refers to methods and analyses used in conservation biology (i.e., measuring biodiversity) and value refers to nonepistemic values. We reviewed and evaluated several landmark articles central to the foundation of conservation biology and concepts of biodiversity with respect to their attempts to separate measures and values. We argue that the measure-value dichotomy is false and that conservation biology can make progress in ways unavailable to other disciplines because its practitioners are tasked with engaging in both the realm of theory and the realm of practice. The entanglement of measures and values is by no means a weakness of conservation biology. Because central concepts such as biodiversity contain both factual and evaluative aspects, conservation biologists can make theoretical progress by examining, reviewing, and forming the values that are an integral part of those concepts. We suggest that values should be included and analyzed with respect to the methods, results, and conclusions of scientific work in conservation biology. © 2016 Society for Conservation Biology.

  6. Precise measurement of renal filtration and vascular parameters using a two-compartment model for dynamic contrast-enhanced MRI of the kidney gives realistic normal values.

    PubMed

    Tofts, Paul S; Cutajar, Marica; Mendichovszky, Iosif A; Peters, A Michael; Gordon, Isky

    2012-06-01

    To model the uptake phase of T(1)-weighted DCE-MRI data in normal kidneys and to demonstrate that the fitted physiological parameters correlate with published normal values. The model incorporates delay and broadening of the arterial vascular peak as it appears in the capillary bed, two distinct compartments for renal intravascular and extravascular Gd tracer, and uses a small-vessel haematocrit value of 24%. Four physiological parameters can be estimated: regional filtration K ( trans ) (ml min(-1) [ml tissue](-1)), perfusion F (ml min(-1) [100 ml tissue](-1)), blood volume v ( b ) (%) and mean residence time MRT (s). From these are found the filtration fraction (FF; %) and total GFR (ml min(-1)). Fifteen healthy volunteers were imaged twice using oblique coronal slices every 2.5 s to determine the reproducibility. Using parenchymal ROIs, group mean values for renal biomarkers all agreed with published values: K ( trans ): 0.25; F: 219; v ( b ): 34; MRT: 5.5; FF: 15; GFR: 115. Nominally cortical ROIs consistently underestimated total filtration (by ~50%). Reproducibility was 7-18%. Sensitivity analysis showed that these fitted parameters are most vulnerable to errors in the fixed parameters kidney T(1), flip angle, haematocrit and relaxivity. These renal biomarkers can potentially measure renal physiology in diagnosis and treatment. • Dynamic contrast-enhanced magnetic resonance imaging can measure renal function. • Filtration and perfusion values in healthy volunteers agree with published normal values. • Precision measured in healthy volunteers is between 7 and 15%.

  7. Work stress, Chinese work values, and work well-being in the Greater China.

    PubMed

    Lu, Luo; Kao, Shu-Fang; Siu, Oi-Ling; Lu, Chang-Qin

    2011-01-01

    Work values influence our attitudes and behavior at work, but they have rarely been explored in the context of work stress. The aim of this research was thus to test direct and moderating effects of Chinese work values (CWV) on relationships between work stressors and work well-being among employees in the Greater China region. A self-administered survey was conducted to collect data from three major cities in the region, namely Beijing, Hong Kong, and Taipei (N = 380). Work stressors were negatively related to work well-being, whereas CWV were positively related to work well-being. In addition, CWV also demonstrated moderating effects in some of the stressor-job satisfaction relationships.

  8. Environments Perceived as Obesogenic Have Lower Residential Property Values

    PubMed Central

    Drewnowski, Adam; Aggarwal, Anju; Rehm, Colin D.; Cohen-Cline, Hannah; Hurvitz, Philip M.; Moudon, Anne V.

    2014-01-01

    Background Studies have tried to link multiple aspects of the built environment with physical activity and obesity rates. Purpose To determine the relation between residential property values and multiple perceived (self-reported) measures of the obesogenic environment. Methods The Seattle Obesity Study (SOS) used a telephone survey of a representative, geographically distributed sample of 2,001 King County adults, collected in 2008–2009 and analyzed in 2012–2013. Home addresses were geocoded. Residential property values at the tax parcel level were obtained from the King County tax assessor. Mean residential property values within a 10-minute walk (833-meter buffer) were calculated for each respondent. Data on multiple perceived measures of the obesogenic environment were collected by self-report. Correlations and multivariable linear regression analyses, stratified by residential density, were used to examine the associations among perceived environmental measures, property values, and BMI. Results Perceived measures of the environment such as crime, heavy traffic, and proximity to bars, liquor stores, and fast food were all associated with lower property values. By contrast, living in neighborhoods that were perceived as safe, quiet, clean, and attractive was associated with higher property values. Higher property values were associated, in turn, with lower BMIs. The observed associations between perceived environment measures and BMI were largely attenuated after accounting for residential property values. Conclusions Perceived measures of obesogenic environments are associated with lower property values. Studies in additional locations need to explore to what extent other perceived environment measures can be reflected in residential property values. PMID:25049218

  9. Evaluation of effective energy for QA and QC: measurement of half-value layer using radiochromic film density.

    PubMed

    Gotanda, T; Katsuda, T; Gotanda, R; Tabuchi, A; Yamamoto, K; Kuwano, T; Yatake, H; Takeda, Y

    2009-03-01

    The effective energy of diagnostic X-rays is important for quality assurance (QA) and quality control (QC). However, the half-value layer (HVL), which is necessary to evaluate the effective energy, is not ubiquitously monitored because ionization-chamber dosimetry is time-consuming and complicated. To verify the applicability of GAFCHROMIC XR type R (GAF-R) film for HVL measurement as an alternative to monitoring with an ionization chamber, a single-strip method for measuring the HVL has been evaluated. Calibration curves of absorbed dose versus film density were generated using this single-strip method with GAF-R film, and the coefficient of determination (r2) of the straight-line approximation was evaluated. The HVLs (effective energies) estimated using the GAF-R film and an ionization chamber were compared. The coefficient of determination (r2) of the straight-line approximation obtained with the GAF-R film was more than 0.99. The effective energies (HVLs) evaluated using the GAF-R film and the ionization chamber were 43.25 keV (5.10 mm) and 39.86 keV (4.45 mm), respectively. The difference in the effective energies determined by the two methods was thus 8.5%. These results suggest that GAF-R might be used to evaluate the effective energy from the film-density growth without the need for ionization-chamber measurements.

  10. Different Institutions and Different Values: Exploring First-Generation Student Fit at 2-Year Colleges

    PubMed Central

    Tibbetts, Yoi; Priniski, Stacy J.; Hecht, Cameron A.; Borman, Geoffrey D.; Harackiewicz, Judith M.

    2018-01-01

    First-generation (FG) college students (students for whom neither parent has a 4-year degree) face a number of challenges as they attempt to obtain a post-secondary degree. They are more likely to come from working-class backgrounds or poverty (Reardon, 2011) and attend lower quality high schools (Warburton et al., 2001) while not benefiting from the guidance of a parent who successfully navigated the path to higher education. FG college students also contend with belonging or “fitting in” concerns due a perceived mismatch between their own values and the values implicit in institutions of higher education (Stephens et al., 2012a). Specifically, prior research has demonstrated that FG college students face an unseen disadvantage that can be attributed to the fact that middle-class norms of independence reflected in American institutions of higher education can be experienced as threatening by many FG students who have been socialized with more interdependent values commonly espoused in working-class populations. The present research examines this theory (cultural mismatch theory) in the understudied context of 2-year colleges and tests if a values-affirmation intervention (i.e., an intervention that has shown promise in addressing identity threats and belonging concerns) can be effective for FG college students at these 2-year campuses. By considering the tenets of cultural mismatch theory in the creation of the values-affirmation interventions we were able to vary different aspects of the intervention in order to examine how its effectiveness may depend on the nature and magnitude of a perceived cultural mismatch. Results from surveying faculty and students at 2-year colleges indicated that compared to traditional 4-year institutions, the norms of 2-year colleges and the motivations of FG students may be different. That is, FG student motives may be more consistent (and thus less mismatched) with the cultural context of 2-year colleges which could result in

  11. Different Institutions and Different Values: Exploring First-Generation Student Fit at 2-Year Colleges.

    PubMed

    Tibbetts, Yoi; Priniski, Stacy J; Hecht, Cameron A; Borman, Geoffrey D; Harackiewicz, Judith M

    2018-01-01

    First-generation (FG) college students (students for whom neither parent has a 4-year degree) face a number of challenges as they attempt to obtain a post-secondary degree. They are more likely to come from working-class backgrounds or poverty (Reardon, 2011) and attend lower quality high schools (Warburton et al., 2001) while not benefiting from the guidance of a parent who successfully navigated the path to higher education. FG college students also contend with belonging or "fitting in" concerns due a perceived mismatch between their own values and the values implicit in institutions of higher education (Stephens et al., 2012a). Specifically, prior research has demonstrated that FG college students face an unseen disadvantage that can be attributed to the fact that middle-class norms of independence reflected in American institutions of higher education can be experienced as threatening by many FG students who have been socialized with more interdependent values commonly espoused in working-class populations. The present research examines this theory (cultural mismatch theory) in the understudied context of 2-year colleges and tests if a values-affirmation intervention (i.e., an intervention that has shown promise in addressing identity threats and belonging concerns) can be effective for FG college students at these 2-year campuses. By considering the tenets of cultural mismatch theory in the creation of the values-affirmation interventions we were able to vary different aspects of the intervention in order to examine how its effectiveness may depend on the nature and magnitude of a perceived cultural mismatch. Results from surveying faculty and students at 2-year colleges indicated that compared to traditional 4-year institutions, the norms of 2-year colleges and the motivations of FG students may be different. That is, FG student motives may be more consistent (and thus less mismatched) with the cultural context of 2-year colleges which could result in fewer

  12. When do drilling alliances add value? The alliance value model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brett, J.F.; Craig, V.B.; Wadsworth, D.B.

    1996-12-31

    A recent GRI report details three previously unstudied aspects of alliances: specific measurable factors that improve alliance success, how a successful alliance should be structured, and when an alliance makes economic sense. The most innovative tool to emerge from the report, the Alliance Value Model, addresses the third aspect. The theory behind the Alliance Value Model is that the long-term viability of any drilling relationship hinges on its ability to create real value and achieve stability. Based upon the report`s findings, the most effective way to form such an alliance is through a detailed description and integration of the technicalmore » processes involved. This new type of process-driven alliance is characterized by a value chain which links together a common set of technical processes, mutually defined bottomline goals, and shared benefits. Building a process-driven alliance requires time and people and therefore has an associated cost. The real value generated by an alliance must exceed this start-up cost. The Alliance Value Model computes the net present value (NPV) of the cash flows for four different operating arrangements: (1) Business As Usual (conventional competitive bidding process), (2) Process-Driven Alliance (linking technical processes to accelerate production and reduce expenses), (3) Incentivized Process-Driven Alliance (linked technical processes with performance incentives to promote stability), and (4) No Drill Case (primarily used to gauge the market value of services). These arrangements test different degrees of process integration between an operator and its suppliers. They can also help determine if the alliance can add enough value to exceed startup costs and if the relationship will be stable. Each partner can test the impact of the relational structure on its own profitability. When an alliance is warranted, all participants can benefit from real value generated in a stable relationship.« less

  13. Measuring H, O, li, B, and BE on Planetary Surfaces: Calibration of Laser-Induced Breakdown Spectroscopy (libs) Data Under Air, Vacuum, and CO2

    NASA Astrophysics Data System (ADS)

    Dyar, M. D.; Nelms, M.; Breves, E. A.

    2012-12-01

    other light elements are directly measured are nearly nonexistent in the 1-2 g quantities needed for LIBS analyses. For this study, we have obtained two sample suites that provide calibrations needed for accurate analyses of H, O, B, Be, and Li in geological samples. The first suite of 11 samples was analyzed for oxygen by fast neutron activation analysis. The second suite includes 11 gem-quality minerals representing the major rock-forming species for B, Li, and Be-rich parageneses. Light elements were directly analyzed using a combination of EMPA, XRF, ion microprobe, uranium extraction, proton-induced gamma-ray emission (PIGE), and prompt gamma-ray neutron activation analysis (PGNAA). LIBS spectra were acquired at Mount Holyoke College under air, vacuum, and CO2 to simulate terrestrial, lunar, and martian environments. Spectra were then used to develop three separate calibration models (one for each environment), enabling LIBS characterization of light elements using multivariate analyses. Results show that when direct analyses of H, O, Li, B, and Be are used rather than LOI results, inferred, or indirectly calculated values, optimal root mean squared errors of prediction result. We are actively adding samples to these calibration suites, and we expect that prediction errors (accuracies) of <1wt% for these elements are possible.

  14. High-Pressure Measurements of Temperature and CO2 Concentration Using Tunable Diode Lasers at 2 μm.

    PubMed

    Cai, Tingdong; Gao, Guangzhen; Wang, Minrui; Wang, Guishi; Liu, Ying; Gao, Xiaoming

    2016-03-01

    A sensor for simultaneous measurements of temperature and carbon dioxide (CO2) concentration at elevated pressure is developed using tunable diode lasers at 2 µm. Based on some selection rules, a CO2 line pair at 5006.140 and 5010.725 cm(-1) is selected for the TDL sensor. In order to ensure the accuracy and rapidity of the sensor, a quasi-fixed-wavelength WMS is employed. Normalization of the 2f signal with the 1f signal magnitude is used to remove the need for calibration and correct for transmission variation due to beam steering, mechanical misalignments, soot, and windows fouling. Temperatures are obtained from comparison of the background-subtracted 1f-normalized WMS-2f signals ratio and a 1f-normalized WMS-2f peak values ratio model. CO2 concentration is inferred from the 1f-normalized WMS-2f peak values of the CO2 transition at 5006.140 cm(-1). Measurements of temperature and CO2 concentration are carried out in static cell experiments (P = 1-10 atm, T = 500-1200 K) to validate the accuracy and ability of the sensor. The results show that accuracy of the sensor for temperature and CO2 concentration are 1.66% temperature and 3.1%, respectively. All the measurements show the potential utility of the sensor for combustion diagnose at elevated pressure. © The Author(s) 2016.

  15. Intensity measurements for the /2, O/ gamma-band of O2, b 1Sigma-g/+/ - X 3Sigma-g/-/

    NASA Technical Reports Server (NTRS)

    Miller, J. H.; Giver, L. P.; Boese, R. W.

    1976-01-01

    Line intensities for the P sub P and P sub Q branches of the (2-O) vibrational band of the magnetic dipole electronic transition for the oxygen red system at 6280 A were measured, and the sum of the R sub R and R sub Q branch intensities was taken. A large number of repetitive spectral scans were required for accuracy, because of low absorption values even at optical path lengths from 300 to 600 m. A total of 557 individual measurements of P-branch lines yielded an intensity value for the P-branches, and equivalent widths for 24 spectral scans yielded an intensity value for the R-branch. R-branch to P-branch intensity ratios were taken for the A-band, B-band, and gamma-band (respectively, O-O at 7620 A, 1-O at 6880 A, and 2-O at 6280 A). Intensities for some rotational lines are found, and effects of combined rotation-vibration interaction are probed.

  16. Identity, Values, and Reflection: Shaping (and Being Shaped) through Assessment

    ERIC Educational Resources Information Center

    Isabella, Marcy; McGovern, Heather

    2018-01-01

    Outlining one program's history of outcomes-based assessment, the authors examine the relationships among assessment practices, program identity, and program values. Understanding the ways in which past processes of identifying learning outcomes reflected, and failed to reflect, shared values points us toward a new set of strategies for developing…

  17. Normative values for optical coherence tomography parameters in healthy children and interexaminer agreement for choroidal thickness measurements.

    PubMed

    Turan, Kadriye Erkan; Sekeroglu, Hande Taylan; Baytaroglu, Ata; Bezci, Figen; Karahan, Sevilay

    2018-01-01

    To (a) determine the normative values for optical coherence tomography (OCT) parameters such as central macular thickness, retinal nerve fiber layer thickness, and choroidal thickness in healthy children; (b) investigate the relationships of these parameters with axial length, central corneal thickness, refractive errors, and intraocular pressure; and (c) determine interexaminer agreement for choroidal thickness measurements. In this cross-sectional study, 120 healthy children aged 8-15 years underwent detailed ophthalmological examination and OCT measurements. Choroidal thickness was measured at three separate locations by two independent examiners. The mean global retinal nerve fiber layer thickness was 98.75 ± 9.45 μm (79.0-121.0). The mean central macular thickness was 232.29 ± 29.37 μm (190.0-376.0). The mean subfoveal choroidal thickness obtained by examiner 1 was 344.38 ± 68.83 μm and that obtained by examiner 2 was 344.04 ± 68.92 μm. Interexaminer agreement was between 99.6%-99.8% for choroidal thickness at three separate locations. Central macular thickness increased with axial length (r=0.245, p=0.007). Choroidal thickness increased with age (r=0.291, p=0.001) and decreased with axial length (r=-0.191, p=0.037). Global retinal nerve fiber layer thickness decreased with axial length (r=-0.247, p=0.007) and increased with central corneal thickness (r=0.208, p=0.022). Global retinal nerve fiber layer thickness positively correlated with choroidal thickness (r=0.354, p<0.001). Global retinal nerve fiber layer thickness (r=0.223, p=0.014) and choroidal thickness (r=0.272, p=0.003) increased with the spherical equivalent (D). Optical coherence tomography parameters showed a wide range of variability in children. Retinal nerve fiber layer thickness, central macular thickness, and choroidal thickness were found to be either inter-related or correlated with age, central corneal thickness, axial length, and refractive errors. Furthermore, manual

  18. High-precision half-life measurements of the T =1 /2 mirror β decays 17F and 33Cl

    NASA Astrophysics Data System (ADS)

    Grinyer, J.; Grinyer, G. F.; Babo, M.; Bouzomita, H.; Chauveau, P.; Delahaye, P.; Dubois, M.; Frigot, R.; Jardin, P.; Leboucher, C.; Maunoury, L.; Seiffert, C.; Thomas, J. C.; Traykov, E.

    2015-10-01

    Background: Measurements of the f t values for T =1 /2 mirror β+ decays offer a method to test the conserved vector current hypothesis and to determine Vud, the up-down matrix element of the Cabibbo-Kobayashi-Maskawa matrix. In most mirror decays used for these tests, uncertainties in the f t values are dominated by the uncertainties in the half-lives. Purpose: Two precision half-life measurements were performed for the T =1 /2 β+ emitters, 17F and 33Cl, in order to eliminate the half-life as the leading source of uncertainty in their f t values. Method: Half-lives of 17F and 33Cl were determined using β counting of implanted radioactive ion beam samples on a moving tape transport system at the Système de Production d'Ions Radioactifs Accélérés en Ligne low-energy identification station at the Grand Accélérateur National d'Ions Lourds. Results: The 17F half-life result, 64.347 (35) s, precise to ±0.05 % , is a factor of 5 times more precise than the previous world average. The half-life of 33Cl was determined to be 2.5038 (22) s. The current precision of ±0.09 % is nearly 2 times more precise compared to the previous world average. Conclusions: The precision achieved during the present measurements implies that the half-life no longer dominates the uncertainty of the f t values for both T =1 /2 mirror decays 17F and 33Cl.

  19. Valuing the Future: Should Educational Benefits Be Discounted?

    ERIC Educational Resources Information Center

    Gilead, Tal

    2015-01-01

    The practice of assigning a lesser value to benefits the further they are into the future, or, in economic terms, discounting, has long played a significant role in shaping public policy. Recently, due to the growing influence of economic modes of thinking on the educational realm, the concept of discounting is also starting to have an influence…

  20. A novel scoring system to measure radiographic abnormalities and related spirometric values in cured pulmonary tuberculosis.

    PubMed

    Báez-Saldaña, Renata; López-Arteaga, Yesenia; Bizarrón-Muro, Alma; Ferreira-Guerrero, Elizabeth; Ferreyra-Reyes, Leticia; Delgado-Sánchez, Guadalupe; Cruz-Hervert, Luis Pablo; Mongua-Rodríguez, Norma; García-García, Lourdes

    2013-01-01

    Despite chemotherapy, patients with cured pulmonary tuberculosis may result in lung functional impairment. To evaluate a novel scoring system based on the degree of radiographic abnormalities and related spirometric values in patients with cured pulmonary tuberculosis. One hundred and twenty seven patients with cured pulmonary tuberculosis were prospectively enrolled in a referral hospital specializing in respiratory diseases. Spirometry was performed and the extent of radiographic abnormalities was evaluated twice by each of two readers to generate a novel quantitative score. Scoring reproducibility was analyzed by the intra-class correlation coefficient (ICC) and the Bland-Altman method. Multiple linear regression models were performed to assess the association of the extent of radiographic abnormalities with spirometric values. The intra-observer agreement for scoring of radiographic abnormalities (SRA) showed an ICC of 0.81 (CI:95%, 0.67-0.95) and 0.78 (CI:95%, 0.65-0.92), for reader 1 and 2, respectively. Inter-observer reproducibility for the first measurement was 0.83 (CI:95%, 0.71-0.95), and for the second measurement was 0.74 (CI:95%, 0.58-0.90). The Bland-Altman analysis of the intra-observer agreement showed a mean bias of 0.87% and -0.55% and an inter-observer agreement of -0.35% and -1.78%, indicating a minor average systematic variability. After adjustment for age, gender, height, smoking status, pack-years of smoking, and degree of dyspnea, the scoring degree of radiographic abnormalities was significantly and negatively associated with absolute and percent predicted values of FVC: -0.07 (CI:95%, -0.01 to -0.04); -2.48 (CI:95%, -3.45 to -1.50); and FEV1 -0.07 (CI:95%, -0.10 to -0.05); -2.92 (CI:95%, -3.87 to -1.97) respectively, in the patients studied. The extent of radiographic abnormalities, as evaluated through our novel scoring system, was inversely associated with spirometric values, and exhibited good reliability and reproducibility. As intra

  1. A Novel Scoring System to Measure Radiographic Abnormalities and Related Spirometric Values in Cured Pulmonary Tuberculosis

    PubMed Central

    Báez-Saldaña, Renata; López-Arteaga, Yesenia; Bizarrón-Muro, Alma; Ferreira-Guerrero, Elizabeth; Ferreyra-Reyes, Leticia; Delgado-Sánchez, Guadalupe; Cruz-Hervert, Luis Pablo; Mongua-Rodríguez, Norma; García-García, Lourdes

    2013-01-01

    Background Despite chemotherapy, patients with cured pulmonary tuberculosis may result in lung functional impairment. Objective To evaluate a novel scoring system based on the degree of radiographic abnormalities and related spirometric values in patients with cured pulmonary tuberculosis. Methods One hundred and twenty seven patients with cured pulmonary tuberculosis were prospectively enrolled in a referral hospital specializing in respiratory diseases. Spirometry was performed and the extent of radiographic abnormalities was evaluated twice by each of two readers to generate a novel quantitative score. Scoring reproducibility was analyzed by the intra-class correlation coefficient (ICC) and the Bland-Altman method. Multiple linear regression models were performed to assess the association of the extent of radiographic abnormalities with spirometric values. Results The intra-observer agreement for scoring of radiographic abnormalities (SRA) showed an ICC of 0.81 (CI:95%, 0.67–0.95) and 0.78 (CI:95%, 0.65–0.92), for reader 1 and 2, respectively. Inter-observer reproducibility for the first measurement was 0.83 (CI:95%, 0.71–0.95), and for the second measurement was 0.74 (CI:95%, 0.58–0.90). The Bland-Altman analysis of the intra-observer agreement showed a mean bias of 0.87% and -0.55% and an inter-observer agreement of -0.35% and -1.78%, indicating a minor average systematic variability. After adjustment for age, gender, height, smoking status, pack-years of smoking, and degree of dyspnea, the scoring degree of radiographic abnormalities was significantly and negatively associated with absolute and percent predicted values of FVC: -0.07 (CI:95%, -0.01 to -0.04); -2.48 (CI:95%, -3.45 to -1.50); and FEV1 -0.07 (CI:95%, -0.10 to -0.05); -2.92 (CI:95%, -3.87 to -1.97) respectively, in the patients studied. Conclusion The extent of radiographic abnormalities, as evaluated through our novel scoring system, was inversely associated with spirometric values, and

  2. The Value of a Well-Being Improvement Strategy: Longitudinal Success across Subjective and Objective Measures Observed in a Firm Adopting a Consumer-Driven Health Plan.

    PubMed

    Guo, Xiaobo; Coberley, Carter; Pope, James E; Wells, Aaron

    2015-10-01

    The objective of this study is to evaluate effectiveness of a firm's 5-year strategy toward improving well-being while lowering health care costs amidst adoption of a Consumer-Driven Health Plan. Repeated measures statistical models were employed to test and quantify association between key demographic factors, employment type, year, individual well-being, and outcomes of health care costs, obesity, smoking, absence, and performance. Average individual well-being trended upward by 13.5% over 5 years, monthly allowed amount health care costs declined 5.2% on average per person per year, and obesity and smoking rates declined by 4.8 and 9.7%, respectively, on average each year. The results show that individual well-being was significantly associated with each outcome and in the expected direction. The firm's strategy was successful in driving statistically significant, longitudinal well-being, biometric and productivity improvements, and health care cost reduction.

  3. Removing traffic emissions from CO2 time series measured at a tall tower using mobile measurements and transport modeling

    NASA Astrophysics Data System (ADS)

    Schmidt, Andres; Rella, Chris W.; Göckede, Mathias; Hanson, Chad; Yang, Zhenlin; Law, Beverly E.

    2014-11-01

    In recent years, measurements of atmospheric carbon dioxide with high precision and accuracy have become increasingly important for climate change research, in particular to inform terrestrial biosphere models. Anthropogenic carbon dioxide emissions from fossil fuel burning have long been recognized to contribute a significant portion of the carbon dioxide in the atmosphere. Here, we present an approach to remove the traffic related carbon dioxide emissions from mole fractions measured at a tall tower by using the corresponding carbon monoxide measurements in combination with footprint analyses and transport modeling. This technique improves the suitability of the CO2 data to be used in inverse modeling approaches of atmosphere-biosphere exchange that do not account for non-biotic portions of CO2. In our study region in Oregon, road traffic emissions are the biggest source of anthropogenic carbon dioxide and carbon monoxide. A three-day mobile campaign covering 1700 km of roads in northwestern Oregon was performed during summer of 2012 using a laser-based Cavity Ring-Down Spectrometer. The mobile measurements incorporated different roads including main highways, urban streets, and back-roads, largely within the typical footprint of a tall CO/CO2 observation tower in Oregon's Willamette Valley. For the first time, traffic related CO:CO2 emission ratios were measured directly at the sources during an on-road campaign under a variety of different driving conditions. An average emission ratio of 7.43 (±1.80) ppb CO per ppm CO2 was obtained for the study region and applied to separate the traffic related portion of CO2 from the mole fraction time series. The road traffic related portion of the CO2 mole fractions measured at the tower site reached maximum values ranging from 9.8 to 12 ppm, depending on the height above the surface, during summer 2012.

  4. Grandmothers’ Familism Values, Adolescent Mothers’ Parenting Efficacy, and Children’s Well-Being

    PubMed Central

    Zeiders, Katharine H.; Umaña-Taylor, Adriana J.; Jahromi, Laudan B.; Updegraff, Kimberly A.

    2016-01-01

    The current study examined intergenerational processes related to familism values among grandmothers, adolescent mothers, and their children. Mexican-origin families (N = 180) participated in in-home interviews during adolescent mothers’ third trimester of pregnancy and 10-, 24-, 48-, and 60-months postpartum. Using longitudinal path analyses, we linked grandmothers’ familism values and behaviors to adolescent mothers’ parenting processes and, in turn, their child’s well-being, taking into account developmentally relevant needs of adolescent mothers. Results revealed that grandmothers’ familism values before the birth of the baby predicted child-rearing support and communication within the grandmother-adolescent mother dyad after the birth of the baby. Support, but not communication, was in turn predictive of adolescent mothers’ parenting self-efficacy, but only at high levels of autonomy granting within the grandmother-adolescent mother dyad. Finally, adolescent mothers’ parenting self-efficacy predicted children’s greater social competence (48 months old), which in turn, predicted greater academic functioning (60 months old). Our findings shed light on the behavioral correlates of familism values within Mexican-origin families with adolescent mothers and highlight the need to consider factors that are developmentally salient (e.g., autonomy) when understanding how familism behaviors benefit adolescent mothers and their children. PMID:26075734

  5. Testing versus guessing blood glucose values: impact on self-care behaviors in type 2 diabetes.

    PubMed

    Pettus, Jeremy; Stenger, Patricia; Schachner, Holly C; Dunne, Nancy; Parkes, Joan Lee; Pardo, Scott; Edelman, Steven V

    2014-09-01

    To assess differences between estimated blood glucose values and those measured on a blood glucose meter and the impact on self-care behavior in type 2 diabetes. Subjects ≥18 years with type 2 diabetes (N = 297) attending a Taking Control of Your Diabetes conference were asked questions about diabetes management and to estimate their current blood glucose. Study staff tested subjects' blood glucose on a meter. After seeing the result, subjects were again asked questions on diabetes management. NCT01453413. The percentage of subject blood glucose estimations that were outside ISO 15197:2003 accuracy criteria (>±15 mg/dL or >±20% of meter glucose values). Nearly half (46%) of subjects estimated blood glucose values outside ISO 15197:2003 accuracy criteria. Time since last blood glucose test, time since last meal, testing frequency, and A1C did not have an effect on differences between estimated blood glucose values and meter results. In the questionnaire before blood glucose testing, most subjects strongly agreed, agreed, or neither agreed nor disagreed that 'I make decisions about my diabetes, such as my food intake or my insulin dose even when I do not test my blood sugar' (71%) and 'My body tells me without testing if my blood sugar is low or high' (77%). After blood glucose testing, 99% of subjects strongly agreed, agreed, or neither agreed nor disagreed that 'Knowing my blood sugar by checking could help me make different diabetes decisions'. Self-monitoring of blood glucose is an important component of diabetes self-management. Testing rather than guessing blood glucose values is important to obtain accurate results and inform people with type 2 diabetes to make effective, appropriate diabetes management decisions. A potential limitation of this study is that the subject population may not be representative of the general population of people with diabetes; however, the conference setting may attract a more motivated population, which could

  6. Epidemiological, demographic, and economic analyses: measurement of the value of trichiasis surgery in The Gambia.

    PubMed

    Frick, K D; Keuffel, E L; Bowman, R J

    2001-07-01

    Untreated trichiasis can lead to corneal opacity. Surgery to prevent the eyelashes from rubbing against the cornea is available, but many individuals with trichiasis never undergo the operation. This study estimates the cost of illness of untreated trichiasis and the willingness to pay for surgery and compares them with the actual cost of providing surgery. The cost of illness estimate is based on trichiasis patient demographics. Data on the implicit price of obtaining surgery and surgical utilization in a matched pair randomized trial are used to infer individual willingness to pay for trichiasis surgery. Patients in the study paid nothing out-of-pocket for surgery; the price of obtaining surgery is the value of the individual's time needed for travel and surgery plus the price of public transportation. The cost of producing surgery was calculated from project records. All monetary figures are reported in 1998 US dollars. The average cost of untreated trichiasis, or the net present value of life-time lost economic productivity, was $89. Individuals facing a lower cost were more likely to undergo an operation; the inferred average willingness to pay was $1.43 (SD 0.244). Surgery cost $6.13 to provide, including $0.86 for transportation to the village. Whether the value of trichiasis surgery exceeds the cost in The Gambia depends on how the value is measured. Individuals are willing to use only limited resources to obtain surgery even though lifetime economic productivity may increase substantially. All three economic measures can be used to inform policy.

  7. Desert Dust Layers Over Polluted Marine Boundary Layers: ACE-2 Measurements and ACE-Asia Plans

    NASA Technical Reports Server (NTRS)

    Russell, Philip B.; Schmid, B.; Livingston, J. M.; Redemann, J.; Bergstrom, R. W.; Condon, Estelle P. (Technical Monitor)

    2000-01-01

    Aerosols in ACE-Asia are expected to have some commonalties with those in ACE-2, along with important differences. Among the commonalities are occurrences of desert dust layers over polluted marine boundary layers. Differences include the nature of the dust (yellowish in the East Asia desert outflow, vs. reddish-brown in the Sahara Outflow measured in ACE-2) and the composition of boundary-layer aerosols (e.g., more absorbing, soot and organic aerosol in-the Asian plume, caused by coal and biomass burning, with limited controls). In this paper we present ACE-2 measurements and analyses as a guide to our plans for ACE-2 Asia. The measurements include: (1) Vertical profiles of aerosol optical depth and extinction (380-1558 nm), and of water vapor column and concentration, from the surface through the elevated desert dust, measured by the 14-channel Ames Airborne Tracking Sunphotometer (AATS-14); (2) Comparisons of airborne and shipborne sunphotometer optical depths to satellite-retrieved values, with and without desert dust; (3) Comparisons between airborne Sunphotometer optical depth and extinction spectra and those derived from coincident airborne in situ measurements of aerosol size distribution, scattering and absorption; (4) Comparisons between size distributions measured in situ and retrieved from sunphotometer optical depth spectra; (5) Comparisons between aerosol single scattering albedo values obtained by several techniques, using various combinations of measurements of backscatter, extinction, size distribution, scattering, absorption, and radiative flux. We show how analyses of these data can be used to address questions important to ACE-Asia, such as: (1) How do dust and other absorbing aerosols affect the accuracy of satellite optical depth retrievals? How important are asphericity effects? (2) How important are supermicron dust and seasalt aerosols to overall aerosol optical depth and radiative forcing? How well are these aerosols sampled by aircraft

  8. Measuring Striving for Understanding and Learning Value of Geometry: A Validity Study

    ERIC Educational Resources Information Center

    Ubuz, Behiye; Aydinyer, Yurdagül

    2017-01-01

    The current study aimed to construct a questionnaire that measures students' personality traits related to "striving for understanding" and "learning value of geometry" and then examine its psychometric properties. Through the use of multiple methods on two independent samples of 402 and 521 middle school students, two studies…

  9. Weekly cycle of NO2 by GOME measurements: A signature of anthropogenic sources

    NASA Astrophysics Data System (ADS)

    Beirle, S.; Platt, U.; Wenig, M.; Wagner, T.

    2003-07-01

    Nitrogen oxides (NO+NO2=NOx) are important trace gases in the troposphere with impact on human health, atmospheric chemistry and climate. Besides natural sources (lightning, soil emissions) and biomass burning, fossil fuel combustion is estimated to be responsible for about 50% of the total production of NOx. Since human activity in industrialized countries largely follows an artificial seven-day cycle, fossil fuel combustion is expected to be reduced during weekends. This "weekend effect" is well known from local, ground based measurements, but has never been analysed on a global scale before. The Global Ozone Monitoring Experiment (GOME) on board the ESA-satellite ERS-2 allows measurements of NO2 column densities. Applying sophisticated algorithms, vertical column densities (VCD) of tropospheric NO2 can be determined. We demonstrate the statistical analysis of weekly cycles of tropospheric NO2 VCDs for different regions of the world. In the cycles of the industrialized regions and cities in the US, Europe and Japan a clear Sunday minimum of tropospheric NO2 VCD can be seen. Sunday NO2 VCDs are about 25-50% lower than working day levels. Metropolitan areas with other religious and cultural backgrounds (Jerusalem, Mecca) show different weekly patterns corresponding to different days of rest. In China, no weekly pattern can be found. The presence of a weekly cycle in the measured tropospheric NO2 VCD allows the identification of anthropogenic sources. In addition, the fraction of emissions subjected to a weekly cycle (mainly transport, power generation) with respect to a constant background (all kind of natural sources, biomass burning, heavy industry) can be estimated. Furthermore, we estimated the lifetime of tropospheric NO2 by analysing the mean weekly cycle over Germany in detail, obtaining a value of about 12 h.

  10. The equivalence of two phylogenetic biodiversity measures: the Shapley value and Fair Proportion index.

    PubMed

    Hartmann, Klaas

    2013-11-01

    Most biodiversity conservation programs are forced to prioritise species in order to allocate their funding. This paper contains a mathematical proof that provides biological support for one common approach based on phylogenetic indices. Phylogenetic trees describe the evolutionary relationships between a group of taxa. Two indices for computing the distinctiveness of each taxon in a phylogenetic tree are considered here-the Shapley value and the Fair Proportion index. These indices provide a measure of the importance of each taxon for overall biodiversity and have been used to prioritise taxa for conservation. The Shapley value is the biodiversity contribution a taxon is expected to make if all taxa are equally likely to become extinct. This interpretation makes it appealing to use the Shapley value in biodiversity conservation applications. The Fair Proportion index lacks a convenient interpretation, however it is significantly easier to calculate and understand. It has been empirically observed that there is a high correlation between the two indices. This paper shows the mathematical basis for this correlation and proves that as the number of taxa increases, the indices become equivalent. Consequently in biodiversity prioritisation the simpler Fair Proportion index can be used whilst retaining the appealing interpretation of the Shapley value.

  11. How well does CO emission measure the H2 mass of MCs?

    NASA Astrophysics Data System (ADS)

    Szűcs, László; Glover, Simon C. O.; Klessen, Ralf S.

    2016-07-01

    We present numerical simulations of molecular clouds (MCs) with self-consistent CO gas-phase and isotope chemistry in various environments. The simulations are post-processed with a line radiative transfer code to obtain 12CO and 13CO emission maps for the J = 1 → 0 rotational transition. The emission maps are analysed with commonly used observational methods, I.e. the 13CO column density measurement, the virial mass estimate and the so-called XCO (also CO-to-H2) conversion factor, and then the inferred quantities (I.e. mass and column density) are compared to the physical values. We generally find that most methods examined here recover the CO-emitting H2 gas mass of MCs within a factor of 2 uncertainty if the metallicity is not too low. The exception is the 13CO column density method. It is affected by chemical and optical depth issues, and it measures both the true H2 column density distribution and the molecular mass poorly. The virial mass estimate seems to work the best in the considered metallicity and radiation field strength range, even when the overall virial parameter of the cloud is above the equilibrium value. This is explained by a systematically lower virial parameter (I.e. closer to equilibrium) in the CO-emitting regions; in CO emission, clouds might seem (sub-)virial, even when, in fact, they are expanding or being dispersed. A single CO-to-H2 conversion factor appears to be a robust choice over relatively wide ranges of cloud conditions, unless the metallicity is low. The methods which try to take the metallicity dependence of the conversion factor into account tend to systematically overestimate the true cloud masses.

  12. The public health value of vaccines beyond efficacy: methods, measures and outcomes.

    PubMed

    Wilder-Smith, A; Longini, I; Zuber, P L; Bärnighausen, T; Edmunds, W J; Dean, N; Spicher, V Masserey; Benissa, M R; Gessner, B D

    2017-07-26

    Assessments of vaccine efficacy and safety capture only the minimum information needed for regulatory approval, rather than the full public health value of vaccines. Vaccine efficacy provides a measure of proportionate disease reduction, is usually limited to etiologically confirmed disease, and focuses on the direct protection of the vaccinated individual. Herein, we propose a broader scope of methods, measures and outcomes to evaluate the effectiveness and public health impact to be considered for evidence-informed policymaking in both pre- and post-licensure stages. Pre-licensure: Regulatory concerns dictate an individually randomised clinical trial. However, some circumstances (such as the West African Ebola epidemic) may require novel designs that could be considered valid for licensure by regulatory agencies. In addition, protocol-defined analytic plans for these studies should include clinical as well as etiologically confirmed endpoints (e.g. all cause hospitalisations, pneumonias, acute gastroenteritis and others as appropriate to the vaccine target), and should include vaccine-preventable disease incidence and 'number needed to vaccinate' as outcomes. Post-licensure: There is a central role for phase IV cluster randomised clinical trials that allows for estimation of population-level vaccine impact, including indirect, total and overall effects. Dynamic models should be prioritised over static models as the constant force of infection assumed in static models will usually underestimate the effectiveness and cost-effectiveness of the immunisation programme by underestimating indirect effects. The economic impact of vaccinations should incorporate health and non-health benefits of vaccination in both the vaccinated and unvaccinated populations, thus allowing for estimation of the net social value of vaccination. The full benefits of vaccination reach beyond direct prevention of etiologically confirmed disease and often extend across the life course of a

  13. 16 CFR 801.10 - Value of voting securities, non-corporate interests and assets to be acquired.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Value of voting securities, non-corporate... ACT OF 1976 COVERAGE RULES § 801.10 Value of voting securities, non-corporate interests and assets to be acquired. Except as provided in § 801.13, the value of voting securities and assets to be acquired...

  14. 16 CFR 801.10 - Value of voting securities, non-corporate interests and assets to be acquired.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Value of voting securities, non-corporate... ACT OF 1976 COVERAGE RULES § 801.10 Value of voting securities, non-corporate interests and assets to be acquired. Except as provided in § 801.13, the value of voting securities and assets to be acquired...

  15. Standard values of maximum tongue pressure taken using newly developed disposable tongue pressure measurement device.

    PubMed

    Utanohara, Yuri; Hayashi, Ryo; Yoshikawa, Mineka; Yoshida, Mitsuyoshi; Tsuga, Kazuhiro; Akagawa, Yasumasa

    2008-09-01

    It is clinically important to evaluate tongue function in terms of rehabilitation of swallowing and eating ability. We have developed a disposable tongue pressure measurement device designed for clinical use. In this study we used this device to determine standard values of maximum tongue pressure in adult Japanese. Eight hundred fifty-three subjects (408 male, 445 female; 20-79 years) were selected for this study. All participants had no history of dysphagia and maintained occlusal contact in the premolar and molar regions with their own teeth. A balloon-type disposable oral probe was used to measure tongue pressure by asking subjects to compress it onto the palate for 7 s with maximum voluntary effort. Values were recorded three times for each subject, and the mean values were defined as maximum tongue pressure. Although maximum tongue pressure was higher for males than for females in the 20-49-year age groups, there was no significant difference between males and females in the 50-79-year age groups. The maximum tongue pressure of the seventies age group was significantly lower than that of the twenties to fifties age groups. It may be concluded that maximum tongue pressures were reduced with primary aging. Males may become weaker with age at a faster rate than females; however, further decreases in strength were in parallel for male and female subjects.

  16. Plug-in hybrid electric vehicle value proposition study. Phase 1, task 2, select value proposition/business model for further study

    DOT National Transportation Integrated Search

    2008-04-01

    The objective of Task 2 is to identify the combination of value propositions that is : believed to be achievable by 2030 and collectively hold promise for a sustainable : PHEV market by 2030. This deliverable outlines what the project team (with inpu...

  17. Setting the equation: establishing value in spine care.

    PubMed

    Resnick, Daniel K; Tosteson, Anna N A; Groman, Rachel F; Ghogawala, Zoher

    2014-10-15

    Topic review. Describe value measurement in spine care and discuss the motivation for, methods for, and limitations of such measurement. Spinal disorders are common and are an important cause of pain and disability. Numerous complementary and competing treatment strategies are used to treat spinal disorders, and the costs of these treatments is substantial and continue to rise despite clear evidence of improved health status as a result of these expenditures. The authors present the economic and legislative imperatives forcing the assessment of value in spine care. The definition of value in health care and methods to measure value specifically in spine care are presented. Limitations to the utility of value judgments and caveats to their use are presented. Examples of value calculations in spine care are presented and critiqued. Methods to improve and broaden the measurement of value across spine care are suggested, and the role of prospective registries in measuring value is discussed. Value can be measured in spine care through the use of appropriate economic measures and patient-reported outcomes measures. Value must be interpreted in light of the perspective of the assessor, the duration of the assessment period, the degree of appropriate risk stratification, and the relative value of treatment alternatives.

  18. Diagnostic value of different adherence measures using electronic monitoring and virologic failure as reference standards.

    PubMed

    Deschamps, Ann E; De Geest, Sabina; Vandamme, Anne-Mieke; Bobbaers, Herman; Peetermans, Willy E; Van Wijngaerden, Eric

    2008-09-01

    Nonadherence to antiretroviral therapy is a substantial problem in HIV and jeopardizes the success of treatment. Accurate measurement of nonadherence is therefore imperative for good clinical management but no gold standard has been agreed on yet. In a single-center prospective study nonadherence was assessed by electronic monitoring: percentage of doses missed and drug holidays and by three self reports: (1) a visual analogue scale (VAS): percentage of overall doses taken; (2) the Swiss HIV Cohort Study Adherence Questionnaire (SHCS-AQ): percentage of overall doses missed and drug holidays and (3) the European HIV Treatment Questionnaire (EHTQ): percentage of doses missed and drug holidays for each antiretroviral drug separately. Virologic failure prospectively assessed during 1 year, and electronic monitoring were used as reference standards. Using virologic failure as reference standard, the best results were for (1) the SHCS-AQ after electronic monitoring (sensitivity, 87.5%; specificity, 78.6%); (2) electronic monitoring (sensitivity, 75%; specificity, 85.6%), and (3) the VAS combined with the SHCS-AQ before electronic monitoring (sensitivity, 87.5%; specificity, 58.6%). The sensitivity of the complex EHTQ was less than 50%. Asking simple questions about doses taken or missed is more sensitive than complex questioning about each drug separately. Combining the VAS with the SHCS-AQ seems a feasible nonadherence measure for daily clinical practice. Self-reports perform better after electronic monitoring: their diagnostic value could be lower when given independently.

  19. Which health technologies should be funded? A prioritization framework based explicitly on value for money.

    PubMed

    Golan, Ofra; Hansen, Paul

    2012-11-26

    Deciding which health technologies to fund involves confronting some of the most difficult choices in medicine. As for other countries, the Israeli health system is faced each year with having to make these difficult decisions. The Public National Advisory Committee, known as 'the Basket Committee', selects new technologies for the basic list of health care that all Israelis are entitled to access, known as the 'health basket'. We introduce a framework for health technology prioritization based explicitly on value for money that enables the main variables considered by decision-makers to be explicitly included. Although the framework's exposition is in terms of the Basket Committee selecting new technologies for Israel's health basket, we believe that the framework would also work well for other countries. Our proposed prioritization framework involves comparing four main variables for each technology: 1. Incremental benefits, including 'equity benefits', to Israel's population; 2. Incremental total cost to Israel's health system; 3. Quality of evidence; and 4. Any additional 'X-factors' not elsewhere included, such as strategic or legal factors, etc. Applying methodology from multi-criteria decision analysis, the multiple dimensions comprising the first variable are aggregated via a points system. The four variables are combined for each technology and compared across the technologies in the 'Value for Money (VfM) Chart'. The VfM Chart can be used to identify technologies that are good value for money, and, given a budget constraint, to select technologies that should be funded. This is demonstrated using 18 illustrative technologies. The VfM Chart is an intuitively appealing decision-support tool for helping decision-makers to focus on the inherent tradeoffs involved in health technology prioritization. Such deliberations can be performed in a systematic and transparent fashion that can also be easily communicated to stakeholders, including the general public

  20. A systematic review of the angular values obtained by computerized photogrammetry in sagittal plane: a proposal for reference values.

    PubMed

    Krawczky, Bruna; Pacheco, Antonio G; Mainenti, Míriam R M

    2014-05-01

    Reference values for postural alignment in the coronal plane, as measured by computerized photogrammetry, have been established but not for the sagittal plane. The objective of this study is to propose reference values for angular measurements used for postural analysis in the sagittal plane for healthy adults. Electronic databases (PubMed, BVS, Cochrane, Scielo, and Science Direct) were searched using the following key words: evaluation, posture, photogrammetry, and software. Articles published between 2006 and 2012 that used the PAS/SAPO (postural assessment software) were selected. Another inclusion criterion was the presentation of, at least, one of the following measurements: head horizontal alignment, pelvic horizontal alignment, hip angle, vertical alignment of the body, thoracic kyphosis, and lumbar lordosis. Angle samples of the selected articles were grouped 2 by 2 in relation to an overall average, which made possible total average, variance, and SD calculations. Six articles were included, and the following average angular values were found: 51.42° ± 4.87° (head horizontal alignment), -12.26° ± 5.81° (pelvic horizontal alignment), -6.40° ± 3.86° (hip angle), and 1.73° ± 0.94° (vertical alignment of the body). None of the articles contained the measurements for thoracic kyphosis and lumbar lordosis. The reference values can be adopted as reference for postural assessment in future researches if the same anatomical points are considered. Copyright © 2014 National University of Health Sciences. Published by Mosby, Inc. All rights reserved.

  1. Lumbar lordosis and sacral slope in lumbar spinal stenosis: standard values and measurement accuracy.

    PubMed

    Bredow, J; Oppermann, J; Scheyerer, M J; Gundlfinger, K; Neiss, W F; Budde, S; Floerkemeier, T; Eysel, P; Beyer, F

    2015-05-01

    Radiological study. To asses standard values, intra- and interobserver reliability and reproducibility of sacral slope (SS) and lumbar lordosis (LL) and the correlation of these parameters in patients with lumbar spinal stenosis (LSS). Anteroposterior and lateral X-rays of the lumbar spine of 102 patients with LSS were included in this retrospective, radiologic study. Measurements of SS and LL were carried out by five examiners. Intraobserver correlation and correlation between LL and SS were calculated with Pearson's r linear correlation coefficient and intraclass correlation coefficients (ICC) were calculated for inter- and intraobserver reliability. In addition, patients were examined in subgroups with respect to previous surgery and the current therapy. Lumbar lordosis averaged 45.6° (range 2.5°-74.9°; SD 14.2°), intraobserver correlation was between Pearson r = 0.93 and 0.98. The measurement of SS averaged 35.3° (range 13.8°-66.9°; SD 9.6°), intraobserver correlation was between Pearson r = 0.89 and 0.96. Intraobserver reliability ranged from 0.966 to 0.992 ICC in LL measurements and 0.944-0.983 ICC in SS measurements. There was an interobserver reliability ICC of 0.944 in LL and 0.990 in SS. Correlation between LL and SS averaged r = 0.79. No statistically significant differences were observed between the analyzed subgroups. Manual measurement of LL and SS in patients with LSS on lateral radiographs is easily performed with excellent intra- and interobserver reliability. Correlation between LL and SS is very high. Differences between patients with and without previous decompression were not statistically significant.

  2. Network analysis of surgical innovation: Measuring value and the virality of diffusion in robotic surgery

    PubMed Central

    Cingolani, Isabella; Panzarasa, Pietro; Darzi, Ara; Athanasiou, Thanos

    2017-01-01

    Background Existing surgical innovation frameworks suffer from a unifying limitation, their qualitative nature. A rigorous approach to measuring surgical innovation is needed that extends beyond detecting simply publication, citation, and patent counts and instead uncovers an implementation-based value from the structure of the entire adoption cascades produced over time by diffusion processes. Based on the principles of evidence-based medicine and existing surgical regulatory frameworks, the surgical innovation funnel is described. This illustrates the different stages through which innovation in surgery typically progresses. The aim is to propose a novel and quantitative network-based framework that will permit modeling and visualizing innovation diffusion cascades in surgery and measuring virality and value of innovations. Materials and methods Network analysis of constructed citation networks of all articles concerned with robotic surgery (n = 13,240, Scopus®) was performed (1974–2014). The virality of each cascade was measured as was innovation value (measured by the innovation index) derived from the evidence-based stage occupied by the corresponding seed article in the surgical innovation funnel. The network-based surgical innovation metrics were also validated against real world big data (National Inpatient Sample–NIS®). Results Rankings of surgical innovation across specialties by cascade size and structural virality (structural depth and width) were found to correlate closely with the ranking by innovation value (Spearman’s rank correlation coefficient = 0.758 (p = 0.01), 0.782 (p = 0.008), 0.624 (p = 0.05), respectively) which in turn matches the ranking based on real world big data from the NIS® (Spearman’s coefficient = 0.673;p = 0.033). Conclusion Network analysis offers unique new opportunities for understanding, modeling and measuring surgical innovation, and ultimately for assessing and comparing generative value between different

  3. The Contradiction Between the Measurement Theory of Quantum Mechanics and the Theory that the Velocity of Any Particle Can Not be Larger than the Velocity of Light

    NASA Technical Reports Server (NTRS)

    Shen, Y.; Shen, Z. J.; Shen, G. T.; Yang, B. C.

    1996-01-01

    By the measurement theory of quantum mechanics and the method of Fourier transform,we proved that the wave function psi(x,y,z,t)= (8/((2(pi)(2L(exp (1/2)))(exp 3))(Phi(L,t,x)Phi(L,t,y)Phi(L,t,z)). According to the theory that the velocity of any particle can not be larger than the velocity of light and the Born interpretation, when absolute value of delta greater than (ct+ L),Phi(L,t,delta) = 0. But according to the calculation, we proved that for some delta, even if absolute value of delta is greater than (ct+L), Phi(L,t,delta) is not equal to 0.

  4. Weekly cycle of NO2 by GOME measurements: a signature of anthropogenic sources

    NASA Astrophysics Data System (ADS)

    Beirle, S.; Platt, U.; Wenig, M.; Wagner, T.

    2003-12-01

    Nitrogen oxides (NO+NO2=NOx and reservoir species) are important trace gases in the troposphere with impact on human health, atmospheric chemistry and climate. Besides natural sources (lightning, soil emissions) and biomass burning, fossil fuel combustion is estimated to be responsible for about 50% of the total production of NOx. Since human activity in industrialized countries largely follows a seven-day cycle, fossil fuel combustion is expected to be reduced during weekends. This "weekend effect" is well known from local, ground based measurements, but has never been analysed on a global scale before. The Global Ozone Monitoring Experiment (GOME) on board the ESA-satellite ERS-2 allows measurements of NO2 column densities. By estimating and subtracting the stratospheric column, and considering radiative transfer, vertical column densities (VCD) of tropospheric NO2 can be determined (e.g. Leue et al., 2001). We demonstrate the statistical analysis of weekly cycles of tropospheric NO2 VCDs for different regions of the world. In the cycles of the industrialized regions and cities in the US, Europe and Japan a clear Sunday minimum of tropospheric NO2 VCD can be seen. Sunday NO2 VCDs are about 25-50% lower than working day levels. Metropolitan areas with other religious and cultural backgrounds (Jerusalem, Mecca) show different weekly patterns corresponding to different days of rest. In China, no weekly pattern can be found. The presence of a weekly cycle in the measured tropospheric NO2 VCD may help to identify the different anthropogenic source categories. Furthermore, we estimated the lifetime of tropospheric NO2 by analysing the mean weekly cycle exemplarily over Germany, obtaining a value of about 6 h in summer and 18-24 h in winter.

  5. An evaluation of a new instrument to measure organisational safety culture values and practices.

    PubMed

    Díaz-Cabrera, D; Hernández-Fernaud, E; Isla-Díaz, R

    2007-11-01

    The main aim of this research is to evaluate a safety culture measuring instrument centred upon relevant organisational values and practices related to the safety management system. Seven dimensions that reflect underlying safety meanings are proposed. A second objective is to explore the four cultural orientations in the field of safety arising from the competing values framework. The study sample consisted of 299 participants from five companies in different sectors. The results show six dimensions of organisational values and practices and different company profiles in the organisations studied. The four cultural orientations proposed by the competing values framework are not confirmed. Nevertheless, a coexistence of diverse cultural orientations or paradoxes in the companies is observed.

  6. The current state of nursing performance measurement, public reporting, and value-based purchasing.

    PubMed

    Kurtzman, Ellen T; Dawson, Ellen M; Johnson, Jean E

    2008-08-01

    Over the last decade, there has been a substantial investment in holding health care providers accountable for the quality of care provided in hospitals and other settings of care. This investment has been realized through the proliferation of national policies that address performance measurement, public reporting, and value-based purchasing. Although nurses represent the largest segment of the health care workforce and despite their acknowledged role in patient safety and health care outcomes, they have been largely absent from policy setting in these areas. This article provides an analysis of current nursing performance measurement and public reporting initiatives and presents a summary of emerging trends in value-based purchasing, with an emphasis on activities in the United States. The article synthesizes issues of relevance to advancing the current climate for nursing quality and concludes with key issues for future policy setting.

  7. Boundary layer measurements of the OH radical in the vicinity of an isolated power plant plume - SO2 and NO2 chemical conversion times

    NASA Technical Reports Server (NTRS)

    Davis, D. D.; Philen, D.; Mcgee, T.; Heaps, W.

    1979-01-01

    Direct measurements of the OH radical in the vicinity of an isolated power plant plume are reported. These measurements were used to estimate the conversion time of SO2 to H2SO4-sulfate aerosol via the initiating step OH + SO2 + M yields HSO3. Using the near-high-noon measured value of OH (9.5 million per cu cm), resulted in a 1/e conversion time of 1.4 days. The latter lifetime would correspond to a conversion rate of about 2%/hr. When the lifetime calculation was modified to take into consideration the OH diurnal cycle, the 1/e conversion time for SO2 was found to be 4.4 days, giving an apparent overall rate of conversion of about 0.7%/hr. Similar calculations carried out for the conversion of NO2 to NHO3 resulted in 1/e lifetimes for NO2 of 2-3 h for midday time periods.

  8. Eddy Covariance measurements of stable CO2 and H2O isotopologues

    NASA Astrophysics Data System (ADS)

    Braden-Behrens, Jelka; Knohl, Alexander

    2015-04-01

    The analysis of the stable isotope composition of CO2 and H2O fluxes (such as 13C, 18O and 2H in H2O and CO2) has provided valuable insights into ecosystem gas exchange. The approach builds on differences in the isotope signature of different ecosystem components that are primarily caused by the preference for or the discrimination against respective isotope species by important processes within the ecosystem (e.g. photosynthesis or leaf water diffusion). With the ongoing development of laser spectrometric methods, fast and precise measurements of isotopologue mixing ratios became possible, hence also enabling Eddy Covariance (EC) based approaches to directly measure the isotopic composition of CO2 and H2Ov net fluxes on ecosystem scale. During an eight month long measurement campaign in 2015, we plan to simultaneously measure CO2 and H2Ov isotopologue fluxes using an EC approach in a managed beech forest in Thuringia, Germany. For this purpose, we will use two different laser spectrometers for high frequency measurements of isotopic compositions: For H2Ov measurements, we will use an off axis cavity output water vapour isotope analyser (WVIA, Los Gatos Research Inc.) with 5 Hz response; and for CO2 measurements, we will use a quantum cascade laser-based system (QCLAS, Aerodyne Research Inc.) with thermoelectrically cooled detectors and up to 10 Hz measurement capability. The resulting continuous isotopologue flux measurements will be accompanied by intensive sampling campaigns on the leaf scale: Water from leaf, twig, soil and precipitation samples will be analysed in the lab using isotope ratio mass spectrometry. During data analysis we will put a focus on (i) the influence of carbon and oxygen discrimination on the isotopic signature of respective net ecosystem exchange, (ii) on the relationship between evapotranspiration and leaf water enrichment, and (iii) on the 18O exchange between carbon dioxide and water. At present, we already carried out extensive

  9. The comparability of the universalism value over time and across countries in the European Social Survey: exact vs. approximate measurement invariance

    PubMed Central

    Zercher, Florian; Schmidt, Peter; Cieciuch, Jan; Davidov, Eldad

    2015-01-01

    Over the last decades, large international datasets such as the European Social Survey (ESS), the European Value Study (EVS) and the World Value Survey (WVS) have been collected to compare value means over multiple time points and across many countries. Yet analyzing comparative survey data requires the fulfillment of specific assumptions, i.e., that these values are comparable over time and across countries. Given the large number of groups that can be compared in repeated cross-national datasets, establishing measurement invariance has been, however, considered unrealistic. Indeed, studies which did assess it often failed to establish higher levels of invariance such as scalar invariance. In this paper we first introduce the newly developed approximate approach based on Bayesian structural equation modeling (BSEM) to assess cross-group invariance over countries and time points and contrast the findings with the results from the traditional exact measurement invariance test. BSEM examines whether measurement parameters are approximately (rather than exactly) invariant. We apply BSEM to a subset of items measuring the universalism value from the Portrait Values Questionnaire (PVQ) in the ESS. The invariance of this value is tested simultaneously across 15 ESS countries over six ESS rounds with 173,071 respondents and 90 groups in total. Whereas, the use of the traditional approach only legitimates the comparison of latent means of 37 groups, the Bayesian procedure allows the latent mean comparison of 73 groups. Thus, our empirical application demonstrates for the first time the BSEM test procedure on a particularly large set of groups. PMID:26089811

  10. Ground-Based Lidar Measurements of Aerosols During ACE-2 Instrument Description, Results, and Comparisons with Other Ground-Based and Airborne Measurements

    NASA Technical Reports Server (NTRS)

    Welton, Ellsworth J.; Voss, Kenneth J.; Gordon, Howard R.; Maring, Hal; Smirnov, Alexander; Holben, Brent; Schmid, Beat; Livingston, John M.; Russell, Philip B.; Durkee, Philip A.; hide

    2000-01-01

    A micro-pulse lidar system (MPL) was used to measure the vertical and horizontal distribution or aerosols during the Aerosol Characterization Experiment 2 (ACE-2) in June and July of 1997. The MPL measurements were made at the Izana observatory (IZO), a weather station located on a mountain ridge (28 deg 18'N, 16 deg 30'W, 2367 m asl) near the center of the island of Tenerife, Canary Islands. The MPL was used to acquire aerosol backscatter, extinction, and optical depth profiles for normal background periods and periods influenced by Saharan dust from North Africa. System tests and calibration procedures are discussed, and in analysis of aerosol optical profiles acquired during ACE-2 is presented. MPL data taken during normal IZO conditions (no dust) showed that upslope aerosols appeared during the day and dissipated at night and that the layers were mostly confined to altitudes a few hundred meters above IZO. MPL data taken during a Saharan dust episode on 17 July showed that peak aerosol extinction values were an order of magnitude greater than molecular scattering over IZO. and that the dust layers extended to 5 km asl. The value of the dust backscatter-extinction ratio was determined to be 0.027 + 0.007 per sr. Comparisons of the MPL data with data from other co-located instruments showed good agreement during the dust episode.

  11. Ground-Based Lidar Measurements of Aerosols During ACE-2: Instrument Description, Results, and Comparisons with Other Ground-Based and Airborne Measurements

    NASA Technical Reports Server (NTRS)

    Welton, Ellsworth J.; Voss, Kenneth J.; Gordon, Howard R.; Maring, Hal; Smirnov, Alexander; Holben, Brent; Schmid, Beat; Livingston, John M.; Russell, Philip B.; Durkee, Philip A.

    2000-01-01

    A micro-pulse lidar system (MPL) was used to measure the vertical and horizontal distribution of aerosols during the Aerosol Characterization Experiment 2 (ACE-2) in June and July of 1997. The MPL measurements were made at the Izana observatory (IZO), a weather station located on a mountain ridge (28 deg 18 min N, 16 deg 30 min W, 2367 m asl) near the center of the island of Tenerife, Canary Islands. The MPL was used to acquire aerosol backscatter, extinction, and optical depth profiles for normal background periods and periods influenced by Saharan dust from North Africa. System tests and calibration procedures are discussed, and an analysis of aerosol optical profiles acquired during ACE-2 is presented. MPL data taken during normal IZO conditions (no dust) showed that upslope aerosols appeared during the day and dissipated at night and that the layers were mostly confined to altitudes a few hundred meters above IZO. MPL data taken during a Saharan dust episode on 17 July showed that peak aerosol extinction values were an order of magnitude greater than molecular scattering over IZO, and that the dust layers extended to 5 km asl. The value of the dust backscatter-extinction ratio was determined to be 0.027 +/- 0.007 sr(exp -1). Comparisons of the MPL data with data from other collocated instruments showed good agreement during the dust episode.

  12. Sex- and Method-Specific Reference Values for Right Ventricular Strain by 2-Dimensional Speckle-Tracking Echocardiography.

    PubMed

    Muraru, Denisa; Onciul, Sebastian; Peluso, Diletta; Soriani, Nicola; Cucchini, Umberto; Aruta, Patrizia; Romeo, Gabriella; Cavalli, Giacomo; Iliceto, Sabino; Badano, Luigi P

    2016-02-01

    Despite the fact that assessment of right ventricular longitudinal strain (RVLS) carries important implications for patient diagnosis, prognosis, and treatment, its implementation in clinical settings has been hampered by the limited reference values and the lack of uniformity in software, method, and definition used for measuring RVLS. Accordingly, this study was designed to establish (1) the reference values for RVLS by 2-dimensional speckle-tracking echocardiography; and (2) their relationship with demographic, hemodynamic, and cardiac factors. In 276 healthy volunteers (55% women; age, 18-76 years), free wall and septum RVLS (6 segments) and free wall RVLS (3 segments) using both 6- and 3-segment regions of interest were obtained. Feasibility of 6-segment RVLS was 92%. Free wall RVLS from 3- versus 6-segment regions of interest had similar values, yet 6-segment region of interest was more feasible (86% versus 73%; P<0.001) and reproducible. Reference values (lower limits of normality) were as follows: 6-segment RVLS, -24.7±2.6% (-20.0%) for men and -26.7±3.1% (-20.3%) for women; 3-segment RVLS, -29.3±3.4% (-22.5%) for men and -31.6±4.0% (-23.3%) for women (P<0.001). Free wall RVLS was 5±2 strain units (%) larger in magnitude than 6-segment RVLS, 10±4% larger than septal RVLS, and 2±4% larger in women than in men (P<0.001). At multivariable analysis, age, sex, pulmonary systolic pressure, right atrial minimal volume, as well as right atrial and left ventricular longitudinal strain resulted as correlates of RVLS values. This is the largest study providing sex- and method-specific reference values for RVLS. Our data may foster the implementation of 2-dimensional speckle-tracking echocardiography-derived RV analysis in clinical practice. © 2016 American Heart Association, Inc.

  13. Calculating Measurement Uncertainty of the “Conventional Value of the Result of Weighing in Air”

    DOE PAGES

    Flicker, Celia J.; Tran, Hy D.

    2016-04-02

    The conventional value of the result of weighing in air is frequently used in commercial calibrations of balances. The guidance in OIML D-028 for reporting uncertainty of the conventional value is too terse. When calibrating mass standards at low measurement uncertainties, it is necessary to perform a buoyancy correction before reporting the result. When calculating the conventional result after calibrating true mass, the uncertainty due to calculating the conventional result is correlated with the buoyancy correction. We show through Monte Carlo simulations that the measurement uncertainty of the conventional result is less than the measurement uncertainty when reporting true mass.more » The Monte Carlo simulation tool is available in the online version of this article.« less

  14. Measurement of the Neutron Electric Form Factor GEN at High Q2

    NASA Astrophysics Data System (ADS)

    McCormick, Kathy

    2003-01-01

    Experiment E02-0131 at Thomas Jefferson National Accelerator Facility (Jefferson Lab) will measure the neutron electric form factor GEn at the high four-momentum transfer values of Q2 ≈ 1.3, 2.4 and 3.4 (GeV/c)2 via a measurement of the cross section asymmetry AT in the reaction {}3vec He(vec e, e'n)pp . This measurement was approved for 32 days of running by Jefferson Lab PAC 212 in January 2002.

  15. Measuring economic value for tourism destination using contingent valuation method: The Sangiran Sites, Central Java Province, Indonesia

    NASA Astrophysics Data System (ADS)

    Subanti, S.; Zukhronah, E.; Handajani, S. S.; Irawan, BRM B.; Hakim, A. R.

    2018-03-01

    This purpose of study aims to estimate the economic value for quality improvement in Sangiran, Indonesia. This paper used contingent valuation method. The study was found significant factors affecting the probability of individuals to be willing to pay for quality improvement are the nominal amount bid, gender, and income. The economic value of Sangiran sites tourism was estimated between Rp 2.219 billion per year until Rp 2.756 billion per year. This value can be a guidance for management of the Sangiran as a basic reason for Sangiran’s improvement. The improvement includes to add the collection, to build supporting infrastructure in Sangiran, to increase services, to arrange training for Sangiran staff, and others. The suggestion from this paper, we must support the local government for Sangiran improvement, because it can be profitable and it can give benefits from many aspects includes economic, historical, and education.

  16. Provider perceptions of the value of same-day, electronic patient-reported measures for use in clinical HIV care

    PubMed Central

    Fredericksen, RJ; Tufano, J; Ralston, J; McReynolds, J; Stewart, M; Lober, WB; Mayer, K; Mathews, WC; Mugavero, M; Crane, PK; Crane, HM

    2016-01-01

    Strong evidence suggests that patient-reported outcomes (PROs) aid in managing chronic conditions, reduce omissions in care, and improve patient-provider communication. However, provider acceptability of PROs and their use in clinical HIV care is not well known. We interviewed providers (n=27) from four geographically diverse HIV and community care clinics in the U.S. that have integrated PROs into routine HIV care, querying perceived value, challenges, and use of PRO data. Perceived benefits included the ability of PROs to identify less-observable behaviors and conditions, particularly suicidal ideation, depression, and substance use; usefulness in agenda-setting prior to a visit; and reduction of social desirability bias in patient-provider communication. Challenges included initial flow integration issues and ease of interpretation of PRO feedback. Providers value same-day, electronic patient-reported measures for use in clinical HIV care with the condition that PROs are 1) tailored to be the most clinically relevant to their population; 2) well-integrated into clinic flow; 3) easy to interpret, highlighting chief patient concerns and changes over time. PMID:27237187

  17. Can Diffusion-Weighted Imaging and Related Apparent Diffusion Coefficient be a Prognostic Value in Women With Breast Cancer?

    PubMed

    Rabasco, Paola; Caivano, Rocchina; Simeon, Vittorio; Dinardo, Giuseppina; Lotumolo, Antonella; Gioioso, Matilde; Villonio, Antonio; Iannelli, Giancarlo; D'Antuono, Felice; Zandolino, Alexis; Macarini, Luca; Guglielmi, Giuseppe; Cammarota, Aldo

    2017-02-07

    To analyze diffusion-weighted imaging (DWI) and the related apparent diffusion coefficient (ADC) in women with breast cancer, correlating these values with the presence at 3 years of distant metastases, and to demonstrate that DWI-Magnetic Resonance Imaging (MRI) and related ADC values may represent a prognostic value in the study of women with breast cancer. Sixty women (aged 45-73 years) affected with breast cancer with a follow-up in 3 years were enrolled. On DWI, we obtained the ADC values, and these were correlated with the clinical condition of patients at 3 years. Moreover, tumour size, lymph node status, and molecular markers, including estrogens receptor, progesterone receptor, Ki-67 index, and human growth factor receptor 2 protein, were correlated with ADC values. This study was approved by the Scientific Committee of our institution. We considered patients with metastasis at 3 years (12 patients - 20%) and without metastasis (48 patients - 80%). The mean ADC value in patients with no metastases at 3 years was 1.06 ± 0.38, while for patients with metastases it was 0.74 ± 0.34 (p = .011). The receiver-operator curve analysis identified a value of 0.75 (<0.75 with risk to develop metastasis) as the best predictive cutoff for ADC values, with the highest sensitivity (81.25%) and higher specificity (66.67%). After regression analysis, ADC value, positivity to estrogen-progestin receptors, and presence of lymph nodes were the only prognostic factors found to be statistically significant. DWI-MRI and related ADC values may represent a prognostic value in women with breast cancer.

  18. Reference values of MRI measurements of the common bile duct and pancreatic duct in children.

    PubMed

    Gwal, Kriti; Bedoya, Maria A; Patel, Neal; Rambhatla, Siri J; Darge, Kassa; Sreedharan, Ram R; Anupindi, Sudha A

    2015-07-01

    the axial measurement was 2.0 mm; the mean coronal measurement of the pancreatic duct was 0.9 mm and the axial measurement was 0.8 mm. Our study provides normative measurements for the common bile duct and pancreatic duct for children up to age 10 years. The upper limits of the CBD and pancreatic duct increase with age, and the values range 1.1-4.0 mm for the CBD and 0.6-1.9 mm for the pancreatic duct.

  19. Derivation & validation of glycosylated haemoglobin (HbA1c) cut-off value as a diagnostic test for type 2 diabetes in south Indian population

    PubMed Central

    Mohan, Alladi; Reddy, S. Aparna; Sachan, Alok; Sarma, K.V.S.; Kumar, D. Prabath; Panchagnula, Mahesh V.; Rao, P.V.L.N. Srinivasa; Kumar, B. Siddhartha; Krishnaprasanthi, P.

    2016-01-01

    Background & Objectives: Glycosylated haemoglobin (HbA1c) has been in use for more than a decade, as a diagnostic test for type 2 diabetes. Validity of HbA1c needs to be established in the ethnic population in which it is intended to be used. The objective of this study was to derive and validate a HbA1c cut-off value for the diagnosis of type 2 diabetes in the ethnic population of Rayalaseema area of south India. Methods: In this cross-sectional study, consecutive patients suspected to have type 2 diabetes underwent fasting plasma glucose (FPG) and 2 h post-load plasma glucose (2 h-PG) measurements after a 75 g glucose load and HbA1c estimation. They were classified as having diabetes as per the American Diabetes Association criteria [(FPG ≥7 mmol/l (≥126 mg/dl) and/or 2 h-PG ≥11.1 mmol/l (≥200 mg/dl)]. In the training data set (n = 342), optimum cut-off value of HbA1c for defining type 2 diabetes was derived by receiver-operator characteristic (ROC) curve method using oral glucose tolerance test results as gold standard. This cut-off was validated in a validation data set (n = 341). Results: On applying HbA1c cut-off value of >6.3 per cent (45 mmol/mol) to the training data set, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for diagnosing type 2 diabetes were calculated to be 90.6, 85.2, 80.8 and 93.0 per cent, respectively. When the same cut-off value was applied to the validation data set, sensitivity, specificity, PPV and NPV were 88.8, 81.9, 74.0 and 92.7 per cent, respectively, although the latter were consistently smaller than the proportions for the training data set, the differences being not significant. Interpretation & conclusions: HbA1c >6.3 per cent (45 mmol/mol) appears to be the optimal cut-off value for the diagnosis of type 2 diabetes applicable to the ethnic population of Rayalaseema area of Andhra Pradesh state in south India. PMID:27934801

  20. Skylab 2 facilities and environmental measurements program

    NASA Technical Reports Server (NTRS)

    1972-01-01

    A list of the facilities and environmental measurements to be monitored in support of the Skylab 2 vehicle is presented. The data include measurement identification number, description, transducer operating range, recorder type, and drawings illustrating measurement location.

  1. A Method for Determining Pseudo-measurement State Values for Topology Observability of State Estimation in Power Systems

    NASA Astrophysics Data System (ADS)

    Urano, Shoichi; Mori, Hiroyuki

    This paper proposes a new technique for determining of state values in power systems. Recently, it is useful for carrying out state estimation with data of PMU (Phasor Measurement Unit). The authors have developed a method for determining state values with artificial neural network (ANN) considering topology observability in power systems. ANN has advantage to approximate nonlinear functions with high precision. The method evaluates pseudo-measurement state values of the data which are lost in power systems. The method is successfully applied to the IEEE 14-bus system.

  2. Hematocrit Measurement with R2* and Quantitative Susceptibility Mapping in Postmortem Brain.

    PubMed

    Walsh, A J; Sun, H; Emery, D J; Wilman, A H

    2018-05-24

    Noninvasive venous oxygenation quantification with MR imaging will improve the neurophysiologic investigation and the understanding of the pathophysiology in neurologic diseases. Available MR imaging methods are limited by sensitivity to flow and often require assumptions of the hematocrit level. In situ postmortem imaging enables evaluation of methods in a fully deoxygenated environment without flow artifacts, allowing direct calculation of hematocrit. This study compares 2 venous oxygenation quantification methods in in situ postmortem subjects. Transverse relaxation (R2*) mapping and quantitative susceptibility mapping were performed on a whole-body 4.7T MR imaging system. Intravenous measurements in major draining intracranial veins were compared between the 2 methods in 3 postmortem subjects. The quantitative susceptibility mapping technique was also applied in 10 healthy control subjects and compared with reference venous oxygenation values. In 2 early postmortem subjects, R2* mapping and quantitative susceptibility mapping measurements within intracranial veins had a significant and strong correlation ( R 2 = 0.805, P = .004 and R 2 = 0.836, P = .02). Higher R2* and susceptibility values were consistently demonstrated within gravitationally dependent venous segments during the early postmortem period. Hematocrit ranged from 0.102 to 0.580 in postmortem subjects, with R2* and susceptibility as large as 291 seconds -1 and 1.75 ppm, respectively. Measurements of R2* and quantitative susceptibility mapping within large intracranial draining veins have a high correlation in early postmortem subjects. This study supports the use of quantitative susceptibility mapping for evaluation of in vivo venous oxygenation and postmortem hematocrit concentrations. © 2018 by American Journal of Neuroradiology.

  3. The robustness of T2 value as a trabecular structural index at multiple spatial resolutions of 7 Tesla MRI.

    PubMed

    Lee, D K; Song, Y K; Park, B W; Cho, H P; Yeom, J S; Cho, G; Cho, H

    2018-04-15

    To evaluate the robustness of MR transverse relaxation times of trabecular bone from spin-echo and gradient-echo acquisitions at multiple spatial resolutions of 7 T. The effects of MRI resolutions to T 2 and T2* of trabecular bone were numerically evaluated by Monte Carlo simulations. T 2 , T2*, and trabecular structural indices from multislice multi-echo and UTE acquisitions were measured in defatted human distal femoral condyles on a 7 T scanner. Reference structural indices were extracted from high-resolution microcomputed tomography images. For bovine knee trabecular samples with intact bone marrow, T 2 and T2* were measured by degrading spatial resolutions on a 7 T system. In the defatted trabecular experiment, both T 2 and T2* values showed strong ( |r| > 0.80) correlations with trabecular spacing and number, at a high spatial resolution of 125 µm 3 . The correlations for MR image-segmentation-derived structural indices were significantly degraded ( |r| < 0.50) at spatial resolutions of 250 and 500 µm 3 . The correlations for T2* rapidly dropped ( |r| < 0.50) at a spatial resolution of 500 µm 3 , whereas those for T 2 remained consistently high ( |r| > 0.85). In the bovine trabecular experiments with intact marrow, low-resolution (approximately 1 mm 3 , 2 minutes) T 2 values did not shorten ( |r| > 0.95 with respect to approximately 0.4 mm 3 , 11 minutes) and maintained consistent correlations ( |r| > 0.70) with respect to trabecular spacing (turbo spin echo, 22.5 minutes). T 2 measurements of trabeculae at 7 T are robust with degrading spatial resolution and may be preferable in assessing trabecular spacing index with reduced scan time, when high-resolution 3D micro-MRI is difficult to obtain. © 2018 International Society for Magnetic Resonance in Medicine.

  4. Measuring resident well-being: impostorism and burnout syndrome in residency.

    PubMed

    Legassie, Jenny; Zibrowski, Elaine M; Goldszmidt, Mark A

    2008-07-01

    Assessing resident well-being is becoming increasingly important from a programmatic standpoint. Two measures that have been used to assess this are the Clance Impostor Scale (CIS) and the Maslach Burnout Inventory-Human Services Survey (MBI-HSS). However, little is known about the relationship between the two phenomena. To explore the prevalence and association between impostorism and burnout syndrome in a sample of internal medicine residents. Anonymous, cross-sectional postal survey. Forty-eight internal medicine residents (postgraduate year [PGY] 1-3) at the Schulich School of Medicine & Dentistry (62.3% response rate). Short demographic questionnaire, CIS and MBI-HSS. Impostorism and burnout syndrome were identified in 43.8% and 12.5% of residents, respectively. With the exception of a negative correlation between CIS scores and the MBI's personal accomplishment subscale (r = -.30; 95% CI -.54 to -.02), no other significant relations were identified. Foreign-trained residents were more likely to score as impostors (odds ratio [OR] 10.7; 95% CI 1.2 to 98.2) while senior residents were more likely to experience burnout syndrome (OR 16.5 95% CI 1.6 to 168.5). Both impostorism and burnout syndrome appear to be threats to resident well-being in our program. The lack of relationship between the two would suggest that programs and researchers wishing to address the issue of resident distress should consider using both measures. The finding that foreign-trained residents appear to be more susceptible to impostorism warrants further study.

  5. Pelvic orientation for total hip arthroplasty in lateral decubitus: can it be accurately measured?

    PubMed

    Sykes, Alice M; Hill, Janet C; Orr, John F; Gill, Harinderjit S; Salazar, Jose J; Humphreys, Lee D; Beverland, David E

    2016-05-16

    During total hip arthroplasty (THA), accurately predicting acetabular cup orientation remains a key challenge, in great part because of uncertainty about pelvic orientation. This pilot study aimed to develop and validate a technique to measure pelvic orientation; establish its accuracy in the location of anatomical landmarks and subsequently; investigate if limb movement during a simulated surgical procedure alters pelvic orientation. The developed technique measured 3-D orientation of an isolated Sawbone pelvis, it was then implemented to measure pelvic orientation in lateral decubitus with post-THA patients (n = 20) using a motion capture system. Orientation of the isolated Sawbone pelvis was accurately measured, demonstrated by high correlations with angular data from a coordinate measurement machine; R-squared values close to 1 for all pelvic axes. When applied to volunteer subjects, largest movements occurred about the longitudinal pelvic axis; internal and external pelvic rotation. Rotations about the anteroposterior axis, which directly affect inclination angles, showed >75% of participants had movement within ±5° of neutral, 0°. The technique accurately measured orientation of the isolated bony pelvis. This was not the case in a simulated theatre environment. Soft tissue landmarks were difficult to palpate repeatedly. These findings have direct clinical relevance, landmark registration in lateral decubitus is a potential source of error, contributing here to large ranges in measured movement. Surgeons must be aware that present techniques using bony landmarks to reference pelvic orientation for cup implantation, both computer-based and mechanical, may not be sufficiently accurate.

  6. Synergetic Combination of Radar Information and Gauge Measurements - with the Conflict between Two Types of Data Being Removed via Displacement and Downscaling

    NASA Astrophysics Data System (ADS)

    Yan, J.; Bardossy, A.

    2017-12-01

    Rain gauges are the foundation in hydrology to collect rainfall data, however, gauge measurements alone are limited at representing the complete rainfall distribution. On the other hand, the reliability of radar data is often limited because of the errors in the radar signal (e.g. clutter, variation of the vertical reflectivity profile, beam blockage, attenuation, etc). Thus, merging radar information and gauge rainfall measurements is in an area of active research. The merging method proposed here is to use the radar data in its [0, 1] format (p-value). The actual precipitation values come from the gauge measurements. At each measurement location, two types of data are available, the radar p-value and the gauge measurement in mm. It happens very frequently that there exists a contradiction between these two types of data. A very likely reason is the influence of the unknown process between the radar measurement height and the surface onto which the hydrometeors fall. A method for quantification of the impact of the unknown process is proposed to fix the conflict, but only to a certain degree. Another possible source that can explain the discrepancy between these two types of data is discretization, i.e., the spatial variability cannot be identified by coarse discretization. Thus, downscaling is also considered to further remove the conflict. Based on the p-value from the radar data and the precipitation from the gauge measurements, a distribution function can be built up. The ultimate goal is to simulate the precipitation field for nowcasting purpose. The conditions to be fulfilled by the simulated field is as the following: honoring the measurements at the gauge locations; sharing a similar pattern with the radar image; preserving the inherent covariance structure. The simulation approach employed here is random mixing. The study domain is located in Reutlingen, Baden-Wuerttemberg, Germany (Latitude 48.49N, Longitude 9.20E). The radar data are obtained from a C

  7. Can T1 w/T2 w ratio be used as a myelin-specific measure in subcortical structures? Comparisons between FSE-based T1 w/T2 w ratios, GRASE-based T1 w/T2 w ratios and multi-echo GRASE-based myelin water fractions.

    PubMed

    Uddin, Md Nasir; Figley, Teresa D; Marrie, Ruth Ann; Figley, Chase R

    2018-03-01

    Given the growing popularity of T 1 -weighted/T 2 -weighted (T 1 w/T 2 w) ratio measurements, the objective of the current study was to evaluate the concordance between T 1 w/T 2 w ratios obtained using conventional fast spin echo (FSE) versus combined gradient and spin echo (GRASE) sequences for T 2 w image acquisition, and to compare the resulting T 1 w/T 2 w ratios with histologically validated myelin water fraction (MWF) measurements in several subcortical brain structures. In order to compare these measurements across a relatively wide range of myelin concentrations, whole-brain T 1 w magnetization prepared rapid acquisition gradient echo (MPRAGE), T 2 w FSE and three-dimensional multi-echo GRASE data were acquired from 10 participants with multiple sclerosis at 3 T. Then, after high-dimensional, non-linear warping, region of interest (ROI) analyses were performed to compare T 1 w/T 2 w ratios and MWF estimates (across participants and brain regions) in 11 bilateral white matter (WM) and four bilateral subcortical grey matter (SGM) structures extracted from the JHU_MNI_SS 'Eve' atlas. Although the GRASE sequence systematically underestimated T 1 w/T 2 w values compared to the FSE sequence (revealed by Bland-Altman and mountain plots), linear regressions across participants and ROIs revealed consistently high correlations between the two methods (r 2 = 0.62 for all ROIs, r 2 = 0.62 for WM structures and r 2 = 0.73 for SGM structures). However, correlations between either FSE-based or GRASE-based T 1 w/T 2 w ratios and MWFs were extremely low in WM structures (FSE-based, r 2 = 0.000020; GRASE-based, r 2 = 0.0014), low across all ROIs (FSE-based, r 2 = 0.053; GRASE-based, r 2 = 0.029) and moderate in SGM structures (FSE-based, r 2 = 0.20; GRASE-based, r 2 = 0.17). Overall, our findings indicated a high degree of correlation (but not equivalence) between FSE-based and GRASE-based T 1 w/T 2 w ratios, and low correlations between T 1 w/T 2 w ratios and MWFs. This

  8. Regional ADC values of the normal brain: differences due to age, gender, and laterality.

    PubMed

    Naganawa, Shinji; Sato, Kimihide; Katagiri, Toshio; Mimura, Takeo; Ishigaki, Takeo

    2003-01-01

    The purpose of this study was to evaluate the stability of measurement for apparent diffusion coefficient (ADC) values in normal brain, to clarify the effect of aging on ADC values, to compare ADC values between men and women, and to compare ADC values between right and left sides of the brain. To evaluate the stability of measurements, five normal volunteers (four men and one woman) were examined five times on different days. Then, 294 subjects with normal MR imaging (147 men and 147 women; age range 20-89 years) were measured. The ADC measurement in normal volunteers was stable. The ADC values stayed within the 5% deviation of average values in all volunteers (mean+/-standard deviation 2.3+/-1.2%). The ADC values gradually increased by aging in all regions. In thalamus, no significant difference was seen between right and left in the subjects under 60 years; however, right side showed higher values in the subjects over 60 years (p<0.01). In the subjects under 60 years, women showed higher values in right frontal, bilateral thalamus, and temporal (p<0.01); however, in the subjects over 60 years, no region showed difference between men and women. The knowledge obtained in this study may be helpful to understand the developmental and aging mechanisms of normal brain and may be useful for the future quantitative study as a reference.

  9. Shipboard Sunphotometer Measurements of Aerosol Optical Depth Spectra and Columnar Water Vapor During ACE-2 and Comparison with Selected Land, Ship, Aircraft, and Satellite Measurements

    NASA Technical Reports Server (NTRS)

    Livingston, John M.; Kapustin, Vladimir N.; Schmid, Beat; Russell, Philip B.; Quinn, Patricia K.; Bates, Timothy S.; Durkee, Philip A.; Smith, Peter J.; Freudenthaler, Volker; Wiegner, Matthias; hide

    2000-01-01

    Analyses of aerosol optical depth (AOD) and colurnmn water vapor (CWV) measurements acquired with NASA Ames Research Center's 6-channel Airborne Tracking Sunphotometer (AATS-6) operated aboard the R/V Professor Vodyanitskiy during the 2nd Aerosol Characterization Experiment (ACE-2) are discussed. Data are compared with various in situ and remote measurements for selected cases. The focus is on 10 July, when the Pelican airplane flew within 70 km of the ship near the time of a NOAA-14/AVHRR satellite overpass and AOD measurements with the 14-channel Ames Airborne Tracking Sunphotometer (AATS-14) above the marine boundary layer (MBL) permitted calculation of AOD within the MBL from the AATS-6 measurements. A detailed column closure test is performed for MBL AOD on 10 July by comparing the AATS-6 MBL AODs with corresponding values calculated by combining shipboard particle size distribution measurements with models of hygroscopic growth and radiosonde humidity profiles (plus assumptions on the vertical profile of the dry particle size distribution and composition). Large differences (30-80% in the mid-visible) between measured and reconstructed AODs are obtained, in large part because of the high sensitivity of the closure methodology to hygroscopic growth models, which vary considerably and have not been validated over the necessary range of particle size/composition distributions. The wavelength dependence of AATS-6 AODs is compared with the corresponding dependence of aerosol extinction calculated from shipboard measurements of aerosol size distribution and of total scattering mearured by a shipboard integrating nephelometer for several days. Results are highly variable, illustrating further the great difficulty of deriving column values from point measurements. AATS-6 CWV values are shown to agree well with corresponding values derived from radiosonde measurements during 8 soundings on 7 days and also with values calculated from measurements taken on 10 July with

  10. It Pays to Be Organized: Organizing Arithmetic Practice around Equivalent Values Facilitates Understanding of Math Equivalence

    ERIC Educational Resources Information Center

    McNeil, Nicole M.; Chesney, Dana L.; Matthews, Percival G.; Fyfe, Emily R.; Petersen, Lori A.; Dunwiddie, April E.; Wheeler, Mary C.

    2012-01-01

    This experiment tested the hypothesis that organizing arithmetic fact practice by equivalent values facilitates children's understanding of math equivalence. Children (M age = 8 years 6 months, N = 104) were randomly assigned to 1 of 3 practice conditions: (a) equivalent values, in which problems were grouped by equivalent sums (e.g., 3 + 4 = 7, 2

  11. An improvement to the ligand optimisation method (LOM) for measuring the apparent dissociation constant and ligand purity in Ca2+ and Mg2+ buffer solutions.

    PubMed

    McGuigan, John A S; Kay, James W; Elder, Hugh Y

    2014-01-01

    In Ca(2+)/Mg(2+) buffers the calculated ionised concentrations ([X(2+)]) can vary by up to a factor of seven. Since there are no defined standards it is impossible to check calculated [X(2+)], making measurement essential. The ligand optimisation method (LOM) is an accurate method to measure [X(2+)] in Ca(2+)/Mg(2+) buffers; independent estimation of ligand purity extends the method to pK(/) < 4. To simplify calculation, Excel programs ALE and AEC were compiled for LOM and its extension. This paper demonstrates that the slope of the electrode in the pX range 2.000-3.301 deviates from Nernstian behaviour as it depends on the value of the lumped interference, Σ. ALE was modified to include this effect; this modified program SALE, and the programs ALE and AEC were used on simulated data for Ca(2+)-EGTA and Mg(2+)-ATP buffers, to calculate electrode and buffer characteristics as a function of Σ. Ca(2+)-electrodes have a Σ < 10(-6) mol/l and there was no difference amongst the three methods. The Σ for Mg(2+)-electrodes lies between 10(-5) and 1.5 (∗) 10(-5) mol/l and calculated [Mg(2+)] with ALE were around 3% less than the true value. SALE and AEC correctly predicted [Mg(2+)]. SALE was used to recalculate K(/) and pK(/) on measured data for Ca(2+)-EGTA and Mg(2+)-EDTA buffers. These results demonstrated that it is pK(/) that is normally distributed. Until defined standards are available, [X(2+)] in Ca(2+)/Mg(2+) buffers have to be measured. The most appropriate method is to use Ca(2+)/Mg(2) electrodes combined with the Excel programs SALE or AEC. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Value-Added and Other Methods for Measuring School Performance: An Analysis of Performance Measurement Strategies in Teacher Incentive Fund Proposals. Research Brief

    ERIC Educational Resources Information Center

    National Center on Performance Incentives, 2008

    2008-01-01

    In "Value-Added and Other Methods for Measuring School Performance: An Analysis of Performance Measurement Strategies in Teacher Incentive Fund Proposals"--a paper presented at the February 2008 National Center on Performance Incentives research to policy conference--Robert Meyer and Michael Christian examine select performance-pay plans…

  13. Measures for Managing Operational Resilience

    DTIC Science & Technology

    2011-07-01

    Measures 4 2.1 Organizational Objectives 4 2.2 High-Value Services and Assets 4 2.3 Controls 5 2.4 Risks 5 2.5 Disruptive Events 6 3...Administrative Agent ESC/XPK 5 Eglin Street Hanscom AFB, MA 01731-2100 NO WARRANTY THIS CARNEGIE MELLON UNIVERSITY AND SOFTWARE ENGINEERING...such as ITIL, COBIT , ISO2700x, BS25999, and PCI DSS, the measures may be useful for measuring security, business continuity, and IT operations

  14. Lower critical field measurements in YBa2Cu3O(6+x) single crystals

    NASA Technical Reports Server (NTRS)

    Kaiser, D. L.; Swartzendruber, L. J.; Gayle, F. W.; Bennett, L. H.

    1991-01-01

    The temperature dependence of the lower critical field in YBa2Cu3O(6+x) single crystals was determined by magnetization measurements with the applied field parallel and perpendicular to the c-axis. Results are compared with data from the literature and fitted to Ginzberg-Landau equations by assuming a linear dependence of the parameter kappa on temperature. A value of 7 plus or minus 2 kOe was estimated for the thermodynamic critical field at T = O by comparison of calculated H (sub c2) values with experimental data from the literature.

  15. Thermal Measurement during Electrolysis of Pd-Ni Thin-film -Cathodes in Li2SO4/H2O Solution

    NASA Astrophysics Data System (ADS)

    Castano, C. H.; Lipson, A. G.; S-O, Kim; Miley, G. H.

    2002-03-01

    Using LENR - open type calorimeters, measurements of excess heat production were carried out during electrolysis in Li_2SO_4/H_2O solution with a Pt-anode and Pd-Ni thin film cathodes (2000-8000 Åthick) sputtered on the different dielectric substrates. In order to accurately evaluate actual performance during electrolysis runs in the open-type calorimeter used, considering effects of heat convection, bubbling and possible H_2+O2 recombination, smooth Pt sheets were used as cathodes. Pt provides a reference since it does not produce excess heat in the light water electrolyte. To increase the accuracy of measurements the water dissociation potential was determined for each cathode taking into account its individual over-voltage value. It is found that this design for the Pd-Ni cathodes resulted in the excess heat production of ~ 20-25 % of input power, equivalent to ~300 mW. In cases of the Pd/Ni- film fracture (or detachment from substrate) no excess heat was detected, providing an added reference point. These experiments plus use of optimized films will be presented.

  16. Comparison of 2 correction methods for absolute values of esophageal pressure in subjects with acute hypoxemic respiratory failure, mechanically ventilated in the ICU.

    PubMed

    Guérin, Claude; Richard, Jean-Christophe

    2012-12-01

    A recent trial showed that setting PEEP according to end-expiratory transpulmonary pressure (P(pl,ee)) in acute lung injury/acute respiratory distress syndrome (ALI/ARDS) might improve patient outcome. P(pl,ee) was obtained by subtracting the absolute value of esophageal pressure (P(es)) from airway pressure an invariant value of 5 cm H(2)O. The goal of the present study was to compare 2 methods for correcting absolute P(es) values in terms of resulting P(pl,ee) and recommended PEEP. Measurements collected prospectively from 42 subjects with various forms of acute hypoxemic respiratory failure receiving mechanical ventilation in ICU were analyzed. P(es) was measured at PEEP (P(es,ee)) and at relaxation volume of the respiratory system Vr (P(es,Vr)), obtained by allowing the subject to exhale into the atmosphere (zero PEEP). Two methods for correcting P(es) were compared: Talmor method (P(pl,ee,Talmor) = P(es,ee) - 5 cm H(2)O), and Vr method (P(es,ee,Vr) = P(es,ee) - P(es,Vr)). The rationale was that P(es,Vr) was a more physiologically based correction factor than an invariant value of 5 cm H(2)O applied to all subjects. Over the 42 subjects, median and interquartile range of P(es,ee) and P(es,Vr) were 11 (7-14) cm H(2)O and 8 (4-11) cm H(2)O, respectively. P(pl,ee,Talmor) was 6 (1-8) cm H(2)O, and P(es,ee,Vr) was 2 (1-5) cm H(2)O (P = .008). Two groups of subjects were defined, based on the difference between the 2 corrected values. In 28 subjects P(pl,ee,Talmor) was ≥ P(es,ee,Vr) (7 [5-9] cm H(2)O vs 2 [1-5] cm H(2)O, respectively), while in 14 subjects P(es,ee,Vr) was > P(pl,ee,Talmor) (2 [0-4] cm H(2)O vs -1 [-3 to 2] cm H(2)O, respectively). P(pl,ee,Vr) was significantly greater than P(pl,ee,Talmor) (7 [5-11] cm H(2)O vs 5 [2-7] cm H(2)O) in the former, and significantly lower in the latter (1 [-2 to 6] cm H(2)O vs 6 [4-9] cm H(2)O). Referring absolute P(es) values to Vr rather than to an invariant value would be better adapted to a patient's physiological

  17. Modeling the Effect of Grain Size Mixing on Thermal Inertia Values Derived from Diurnal and Seasonal THEMIS Measurements

    NASA Astrophysics Data System (ADS)

    McCarty, C.; Moersch, J.

    2017-12-01

    Sedimentary processes have slowed over Mars' geologic history. Analysis of the surface today can provide insight into the processes that may have affected it over its history. Sub-resolved checkerboard mixtures of materials with different thermal inertias (and therefore different grain sizes) can lead to differences in thermal inertia values inferred from night and day radiance observations. Information about the grain size distribution of a surface can help determine the degree of sorting it has experienced or it's geologic maturity. Standard methods for deriving thermal inertia from measurements made with THEMIS can give values for the same location that vary by as much as 20% between scenes. Such methods make the assumption that each THEMIS pixel contains material that has uniform thermophysical properties. Here we propose that if a mixture of small and large particles is present within a pixel, the inferred thermal inertia will be strongly dominated by whichever particle is warmer at the time of the measurement because the power radiated by a surface is proportional (by the Stefan-Boltzmann law) to the fourth power of its temperature. This effect will result in a change in thermal inertia values inferred from measurements taken at different times of day and night. Therefore, we expect to see correlation between the magnitude of diurnal variations in inferred thermal inertia values and the degree of grain size mixing for a given pixel location. Preliminary work has shown that the magnitude of such diurnal variation in inferred thermal inertias is sufficient to detect geologically useful differences in grain size distributions. We hypothesize that at least some of the 20% variability in thermal inertias inferred from multiple scenes for a given location could be attributed to sub-pixel grain size mixing rather than uncertainty inherent to the experiment, as previously thought. Mapping the difference in inferred thermal inertias from day and night THEMIS

  18. Supplementary comparisons of COOMET in the field of measurements of liquids kinematical viscosity COOMET.M.V-S2

    NASA Astrophysics Data System (ADS)

    Demyanov, A. A.; Tsurko, A. A.

    2017-01-01

    In the comparisons three Newtonian liquid samples were used with nominal values of 20 mm2/s 100 mm2/s and 1000 mm2/s ('20', '100' and '1000', respectively) at 20 °C. Each NMI presented results of measurements values kinematic viscosity samples, uncertainty and uncertainty budget. The purpose of these comparisons was confirmation of measurement and calibration capabilities (CMC) of the relevant NMI. As a reference the values of kinematic viscosity reference samples were taken as average values of measurement results obtained in the research laboratory of the national standards and research in the field of measurements of viscosity and density of the D I Mendeleev Institute for Metrology (VNIIM, RF), as a participant in international comparisons CCM.V-K1, BIPM. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  19. Which health technologies should be funded? A prioritization framework based explicitly on value for money

    PubMed Central

    2012-01-01

    Background Deciding which health technologies to fund involves confronting some of the most difficult choices in medicine. As for other countries, the Israeli health system is faced each year with having to make these difficult decisions. The Public National Advisory Committee, known as ‘the Basket Committee’, selects new technologies for the basic list of health care that all Israelis are entitled to access, known as the ‘health basket’. We introduce a framework for health technology prioritization based explicitly on value for money that enables the main variables considered by decision-makers to be explicitly included. Although the framework’s exposition is in terms of the Basket Committee selecting new technologies for Israel’s health basket, we believe that the framework would also work well for other countries. Methods Our proposed prioritization framework involves comparing four main variables for each technology: 1. Incremental benefits, including ‘equity benefits’, to Israel’s population; 2. Incremental total cost to Israel’s health system; 3. Quality of evidence; and 4. Any additional ‘X-factors’ not elsewhere included, such as strategic or legal factors, etc. Applying methodology from multi-criteria decision analysis, the multiple dimensions comprising the first variable are aggregated via a points system. Results The four variables are combined for each technology and compared across the technologies in the ‘Value for Money (VfM) Chart’. The VfM Chart can be used to identify technologies that are good value for money, and, given a budget constraint, to select technologies that should be funded. This is demonstrated using 18 illustrative technologies. Conclusions The VfM Chart is an intuitively appealing decision-support tool for helping decision-makers to focus on the inherent tradeoffs involved in health technology prioritization. Such deliberations can be performed in a systematic and transparent fashion that can also be

  20. The cutoff values of indirect indices for measuring insulin resistance for metabolic syndrome in Korean children and adolescents.

    PubMed

    Kim, Jun Woo; Park, Sang Hoo; Kim, Yoojin; Im, Minji; Han, Heon-Seok

    2016-09-01

    The prevalence rates of metabolic syndrome (MetS) and percentile distribution of insulin resistance (IR) among Korean children and adolescents were investigated. The cutoff values of IR were calculated to identify high-risk MetS groups. Data from 3,313 Korean subjects (1,756 boys and 1,557 girls, aged 10-18 years) were included from the Korean National Health and Nutrition Examination Survey conducted during 2007-2010. Three different sets of criteria for MetS were used. Indirect measures of IR were homeostasis model assessment (HOMA-IR) and triglyceride and glucose (TyG) index. The cutoff values of the HOMA-IR and TyG index were obtained from the receiver operation characteristic curves. According to the MetS criteria of de Ferranti el al., Cook et al., and the International Diabetes Federation, the prevalence rates in males and females were 13.9% and 12.3%, 4.6% and 3.6%, and 1.4% and 1.8%, respectively. Uses these 3 criteria, the cutoff values of the HOMA-IR and TyG index were 2.94 and 8.41, 3.29 and 8.38, and 3.54 and 8.66, respectively. The cutoff values using each of the 3 criteria approximately corresponds to the 50th-75th, 75th, and 75th-90th percentiles of normal HOMA-IR and TyG index levels. This study describes the prevalence rates of MetS in Korean children and adolescents, an index of IR, and the cutoff values for MetS with the aim of detecting high-risk groups. The usefulness of these criteria needs to be verified by further evaluation.