46 CFR 199.45 - Tests and inspections of lifesaving equipment and arrangements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... rescue boats, including engines and release mechanisms; (3) The proper condition of flotation equipment... indicating radiobeacons (EPIRB), search and rescue transponders (SART), and pyrotechnic signaling devices; (5... repeated; (2) The proper condition and operation of lifeboats and rescue boats, including engines and...

Environmental Assessment for Hawaii Tracking Station A-Side Antenna Remote Block Change Upgrade at Kaena Point Satellite Tracking Station, Hawaii

DTIC Science & Technology

2011-02-01

Heating, Ventilation, Air Conditioning (HVAC) system to environmentally control the HPA Room as well as a Mechanical Room to house the new diesel ...Rickie D. Moon, Senior Systems Engineer MS, Environmental Management, Samford University BS, Chemistry and Mathematics, Samford University 28...Huntsville 16 LPES, Inc. Timothy Lavallee, PE, Principal/Senior Engineer BS, Mechanical Engineering , Northeastern University MS, Civil and

Training for Engineering Craftsmen: The Module System.

ERIC Educational Resources Information Center

Engineering Industry Training Board, London (England).

New arrangements for craft training in the British engineering industry call for a three stage structure: (1) a year of basic training in a wide variety of skills (welding, vehicle painting, electrical engineering, mechanical engineering, and others); (2) selected training in specialized skills under controlled conditions; (3) experience in using…

On the energy efficiency of cyclic mechanisms

NASA Astrophysics Data System (ADS)

Briskin, E. S.; Kalinin, Ya. V.; Maloletov, A. V.; Chernyshev, V. V.

2014-01-01

We consider cyclic mechanisms with one degree of freedom driven by engines of various types such as alternating and direct current motors, internal combustion engines, etc. We pose the problem of modifying the mechanism structure by joining additional links or by varying the parameters or operation mode of the original mechanism so as to minimize the thermal losses in the driving motor. The solution is based on the minimization of the functional determining the irreversible power losses. We show that, for the engines considered, all cyclic mechanisms with one degree of freedom should satisfy a fundamental condition ensuring the minimum of losses. We consider two examples, one of which corresponds to actually existing mechanisms.

Engineering of arteries in vitro

PubMed Central

Huang, Angela H.; Niklason, Laura E.

2014-01-01

This review will focus on two elements that are essential for functional arterial regeneration in vitro: the mechanical environment and the bioreactors used for tissue growth. The importance of the mechanical environment to embryological development, vascular functionality, and vascular graft regeneration will be discussed. Bioreactors generate mechanical stimuli to simulate the biomechanical environment of the arterial system. This system has been used to reconstruct arterial grafts with appropriate mechanical strength for implantation by controlling the chemical and mechanical environments in which the grafts are grown. Bioreactors are powerful tools to study the effect of mechanical stimuli on extracellular matrix (ECM) architecture and the mechanical properties of engineered vessels. Hence biomimetic systems enable us to optimize chemo-biomechanical culture conditions to regenerate engineered vessels with physiological properties similar to those of native arterial vessels. In addition, this review will introduce and examine various approaches and techniques that have been used to engineer biologically-based vascular grafts, including collagen-based grafts, fibrin-gel grafts, cell sheet engineering, biodegradable polymers, and decellularization of native vessels. PMID:24399290

Modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues.

PubMed

Argento, G; de Jonge, N; Söntjens, S H M; Oomens, C W J; Bouten, C V C; Baaijens, F P T

2015-06-01

The anisotropic collagen architecture of an engineered cardiovascular tissue has a major impact on its in vivo mechanical performance. This evolving collagen architecture is determined by initial scaffold microstructure and mechanical loading. Here, we developed and validated a theoretical and computational microscale model to quantitatively understand the interplay between scaffold architecture and mechanical loading on collagen synthesis and degradation. Using input from experimental studies, we hypothesize that both the microstructure of the scaffold and the loading conditions influence collagen turnover. The evaluation of the mechanical and topological properties of in vitro engineered constructs reveals that the formation of extracellular matrix layers on top of the scaffold surface influences the mechanical anisotropy on the construct. Results show that the microscale model can successfully capture the collagen arrangement between the fibers of an electrospun scaffold under static and cyclic loading conditions. Contact guidance by the scaffold, and not applied load, dominates the collagen architecture. Therefore, when the collagen grows inside the pores of the scaffold, pronounced scaffold anisotropy guarantees the development of a construct that mimics the mechanical anisotropy of the native cardiovascular tissue.

Estimation of the physiological mechanical conditioning in vascular tissue engineering by a predictive fluid-structure interaction approach.

PubMed

Tresoldi, Claudia; Bianchi, Elena; Pellegata, Alessandro Filippo; Dubini, Gabriele; Mantero, Sara

2017-08-01

The in vitro replication of physiological mechanical conditioning through bioreactors plays a crucial role in the development of functional Small-Caliber Tissue-Engineered Blood Vessels. An in silico scaffold-specific model under pulsatile perfusion provided by a bioreactor was implemented using a fluid-structure interaction (FSI) approach for viscoelastic tubular scaffolds (e.g. decellularized swine arteries, DSA). Results of working pressures, circumferential deformations, and wall shear stress on DSA fell within the desired physiological range and indicated the ability of this model to correctly predict the mechanical conditioning acting on the cells-scaffold system. Consequently, the FSI model allowed us to a priori define the stimulation pattern, driving in vitro physiological maturation of scaffolds, especially with viscoelastic properties.

Pre-Employment Laboratory Training. General Agricultural Mechanics Volume I. Instructional Materials.

ERIC Educational Resources Information Center

Texas A and M Univ., College Station. Vocational Instructional Services.

This course outline, the first volume of a two-volume set, consists of lesson plans for pre-employment laboratory training in general agricultural mechanics. Covered in the 12 lessons included in this volume are selecting tractors and engines, diagnosing engine conditions, servicing electrical systems, servicing cooling systems, servicing fuel and…

Passaged adult chondrocytes can form engineered cartilage with functional mechanical properties: a canine model.

PubMed

Ng, Kenneth W; Lima, Eric G; Bian, Liming; O'Conor, Christopher J; Jayabalan, Prakash S; Stoker, Aaron M; Kuroki, Keiichi; Cook, Cristi R; Ateshian, Gerard A; Cook, James L; Hung, Clark T

2010-03-01

It was hypothesized that previously optimized serum-free culture conditions for juvenile bovine chondrocytes could be adapted to generate engineered cartilage with physiologic mechanical properties in a preclinical, adult canine model. Primary or passaged (using growth factors) adult chondrocytes from three adult dogs were encapsulated in agarose, and cultured in serum-free media with transforming growth factor-beta3. After 28 days in culture, engineered cartilage formed by primary chondrocytes exhibited only small increases in glycosaminoglycan content. However, all passaged chondrocytes on day 28 elaborated a cartilage matrix with compressive properties and glycosaminoglycan content in the range of native adult canine cartilage values. A preliminary biocompatibility study utilizing chondral and osteochondral constructs showed no gross or histological signs of rejection, with all implanted constructs showing excellent integration with surrounding cartilage and subchondral bone. This study demonstrates that adult canine chondrocytes can form a mechanically functional, biocompatible engineered cartilage tissue under optimized culture conditions. The encouraging findings of this work highlight the potential for tissue engineering strategies using adult chondrocytes in the clinical treatment of cartilage defects.

Carbon nanotube-like materials in the exhaust from a diesel engine using gas oil/ethanol mixing fuel with catalysts and sulfur.

PubMed

Suzuki, Shunsuke; Mori, Shinsuke

2017-08-01

Particulate matter from a diesel engine, including soot and carbon nanomaterials, was collected on a sampling holder and the structure of the materials was studied by transmission electron microscopy (TEM) and scanning electron microscopy (SEM). As a result of employing gas oil/ethanol mixing fuel with sulfur and ferrocene/molybdenum as catalyst sources, formation of carbon nanotubes (CNT)-like materials in addition to soot was observed in the exhaust gas from a diesel engine. It was revealed that CNT-like materials were included among soot in our system only when the following three conditions were satisfied simultaneously: high ethanol fraction in fuel, high sulfur loading, and presence of catalyst sources in fuel. This study confirmed that if at least one of these three conditions was not satisfied, CNT-like materials were not observed in the exhaust from a diesel engine. These experimental results shown in this work provide insights into understanding CNT-like material formation mechanism in a diesel engine. Recent papers reported that carbon nanotube-like materials were included in the exhaust gas from engines, but conditions for carbon nanotube-like material formation have not been well studied. This work provides the required conditions for carbon nanotube-like material growth in a diesel engine, and this will be helpful for understanding the carbon nanotube-like material formation mechanism and taking countermeasures to preventing carbon nanotube-like material formation in a diesel engine.

Job Prospects in HVAC Engineering.

ERIC Educational Resources Information Center

Basta, Nicholas

1985-01-01

Although heating, ventilation, and air conditioning (HVAC) engineering degrees are not offered, there is a serious need for specialists and consultants in this area (since most have been trained as mechanical engineers). Opportunities exist for individuals possessing a customer-oriented attitude, with knowledge in computerized controls, innovative…

High-Heat-Flux Cyclic Durability of Thermal and Environmental Barrier Coatings

NASA Technical Reports Server (NTRS)

Zhu, Dongming; Ghosn, Louis L.; Miller, Robert A.

2007-01-01

Advanced ceramic thermal and environmental barrier coatings will play an increasingly important role in future gas turbine engines because of their ability to protect the engine components and further raise engine temperatures. For the supersonic vehicles currently envisioned in the NASA fundamental aeronautics program, advanced gas turbine engines will be used to provide high power density thrust during the extended supersonic flight of the aircraft, while meeting stringent low emission requirements. Advanced ceramic coating systems are critical to the performance, life and durability of the hot-section components of the engine systems. In this work, the laser and burner rig based high-heat-flux testing approaches were developed to investigate the coating cyclic response and failure mechanisms under simulated supersonic long-duration cruise mission. The accelerated coating cracking and delamination mechanism under the engine high-heat-flux, and extended supersonic cruise time conditions will be addressed. A coating life prediction framework may be realized by examining the crack initiation and propagation in conjunction with environmental degradation under high-heat-flux test conditions.

Effect of soot on oil properties and wear of engine components

NASA Astrophysics Data System (ADS)

Green, D. A.; Lewis, R.

2007-09-01

The objective of the work outlined in this paper was to increase the understanding of the wear mechanisms that occur within a soot contaminated contact zone, to help in future development of a predictive wear model to assist in the automotive engine valve train design process. The paper builds on previous work by the author, through testing of different lubricants and increased levels of soot contamination. Wear testing has been carried out using specimens operating under realistic engine conditions, using a reciprocating test-rig specifically designed for this application, where a steel disc is held in a heated bath of oil and a steel ball is attached to a reciprocating arm (replicating a sliding elephant's foot valve train contact). Detailed analysis of the test specimens has been performed using scanning electron microscopy to identify wear features relating to the proposed wear mechanisms. Analysis of worn engine components from durability engine tests has also been carried out for a comparison between specimen tests and engine testing. To assist the understanding of the wear test results obtained, the physical properties of contaminated lubricants were investigated, through viscosity, traction and friction measurements. The results have revealed how varying lubrication conditions change the wear rate of engine components and determine the wear mechanism that dominates in specific situations. Testing has also shown the positive effects of advanced engine lubricants to reduce the amount of wear produced with soot present.

24 CFR 3280.4 - Incorporation by reference.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Floor, Arlington, VA 22209-2403 ASCE—American Society of Civil Engineers, 345 East 47th Street, New York, New York 10017-2398 ASHRAE—American Society of Heating, Refrigeration and Air Conditioning Engineers, 1791 Tulle Circle, NE., Atlanta, Georgia 30329 ASME—American Society of Mechanical Engineers, 345 East...

Mechanical equivalent of quantum heat engines.

PubMed

Arnaud, Jacques; Chusseau, Laurent; Philippe, Fabrice

2008-06-01

Quantum heat engines employ as working agents multilevel systems instead of classical gases. We show that under some conditions quantum heat engines are equivalent to a series of reservoirs at different altitudes containing balls of various weights. A cycle consists of picking up at random a ball from one reservoir and carrying it to the next, thereby performing or absorbing some work. In particular, quantum heat engines, employing two-level atoms as working agents, are modeled by reservoirs containing balls of weight 0 or 1. The mechanical model helps us prove that the maximum efficiency of quantum heat engines is the Carnot efficiency. Heat pumps and negative temperatures are considered.

Modeling of rolling element bearing mechanics

NASA Technical Reports Server (NTRS)

Greenhill, L. M.

1991-01-01

Roller element bearings provide the primary mechanical interface between rotating and nonrotating components in the high performance turbomachinery of the Space Shuttle Main Engine (SSME). Knowledge of bearing behavior under various loading and environmental conditions is essential to predicting and understanding the overall behavior of turbopumps, including rotordynamic stability, critical speeds and bearing life. The objective is to develop mathematical models and computer programs to describe the mechanical behavior of ball and cylinder roller bearings under the loading and environmental conditions encountered in the SSME and future high performance rocket engines. This includes characteristics such as nonlinear load/motion relationships, stiffness and damping, rolling element loads for life prediction, and roller and cage stability.

Theories of central engine for long gamma-ray bursts

NASA Astrophysics Data System (ADS)

Nagataki, Shigehiro

2018-02-01

Long GRBs are the most powerful explosions in the universe since the Big Bang. At least, some fraction of long GRBs are born from the death of massive stars. Likewise, only some fraction of massive stars that satisfy additional special conditions explode as long GRBs associated with supernovae/hypernovae. In this paper, we discuss the explosion mechanism of long GRBs associated with hypernovae: ‘the central engine of long GRBs’. The central engine of long GRBs is very different from that of core-collapse supernovae, although the mechanism of the engine is still not firmly established. In this paper, we review theoretical studies of the central engine of long GRBs. First, we discuss possible progenitor stars. Then several promising mechanisms of the central engine—such as black hole and magnetar formation—will be reviewed. We will also mention some more exotic models. Finally, we describe prospects for future studies of the central engine of long GRBs.

The use of telemetry in testing in high performance racing engines

NASA Astrophysics Data System (ADS)

Hauser, E.

Telemetry measurement data in mobile application and under difficult environmental conditions were recorded. All relevant racing car and engine parameters were measured: pressure, stress, temperature, acceleration, ignition, number of revolutions, control of electronic injection, and flow measurements on the car body. The difficult measuring conditions due to high voltage ignition, mechanical loads and vibrations impose special requirements on a telemetry system built in racing cars. It has to be compact, flexible, light, and mechanically robust and has to fulfil special sheilding conditions. The measured data are transfered to a stationary measurement car via a radio line, involving RF communication problems. The measured data are directly displayed and evaluated in the measurement car.

Creep Behavior of Hafnia and Ytterbium Silicate Environmental Barrier Coating Systems on SiC/SiC Ceramic Matrix Composites

NASA Technical Reports Server (NTRS)

Zhu, Dongming; Fox, Dennis S.; Ghosn, Louis J.; Harder, Bryan

2011-01-01

Environmental barrier coatings will play a crucial role in future advanced gas turbine engines because of their ability to significantly extend the temperature capability and stability of SiC/SiC ceramic matrix composite (CMC) engine components, thus improving the engine performance. In order to develop high performance, robust coating systems for engine components, appropriate test approaches simulating operating temperature gradient and stress environments for evaluating the critical coating properties must be established. In this paper, thermal gradient mechanical testing approaches for evaluating creep and fatigue behavior of environmental barrier coated SiC/SiC CMC systems will be described. The creep and fatigue behavior of Hafnia and ytterbium silicate environmental barrier coatings on SiC/SiC CMC systems will be reported in simulated environmental exposure conditions. The coating failure mechanisms will also be discussed under the heat flux and stress conditions.

In vitro physical stimulation of tissue-engineered and native cartilage.

PubMed

Li, Kelvin W; Klein, Travis J; Chawla, Kanika; Nugent, Gayle E; Bae, Won C; Sah, Robert L

2004-01-01

Because of the limited availability of donor cartilage for resurfacing defects in articular surfaces, there is tremendous interest in the in vitro bioengineering of cartilage replacements for clinical applications. However, attaining mechanical properties in engineered cartilaginous constructs that approach those of native cartilage has not been previously achieved when constructs are cultured under free-swelling conditions. One approach toward stimulating the development of constructs that are mechanically more robust is to expose them to physical environments that are similar, in certain ways, to those encountered by native cartilage. This is a strategy motivated by observations in numerous short-term experiments that certain mechanical signals are potent stimulators of cartilage metabolism. On the other hand, excess mechanical loading can have a deleterious effect on cartilage. Culture conditions that include a physical stimulation component are made possible by the use of specialized bioreactors. This chapter addresses some of the issues involved in using bioreactors as integral components of cartilage tissue engineering and in studying the physical regulation of cartilage. We first consider the generation of cartilaginous constructs in vitro. Next we describe the rationale and design of bioreactors that can impart either mechanical deformation or fluid-induced mechanical signals.

Optimal tuning of a confined Brownian information engine.

PubMed

Park, Jong-Min; Lee, Jae Sung; Noh, Jae Dong

2016-03-01

A Brownian information engine is a device extracting mechanical work from a single heat bath by exploiting the information on the state of a Brownian particle immersed in the bath. As for engines, it is important to find the optimal operating condition that yields the maximum extracted work or power. The optimal condition for a Brownian information engine with a finite cycle time τ has been rarely studied because of the difficulty in finding the nonequilibrium steady state. In this study, we introduce a model for the Brownian information engine and develop an analytic formalism for its steady-state distribution for any τ. We find that the extracted work per engine cycle is maximum when τ approaches infinity, while the power is maximum when τ approaches zero.

Multiaxial and Thermomechanical Fatigue of Materials: A Historical Perspective and Some Future Challenges

NASA Technical Reports Server (NTRS)

Kalluri, Sreeramesh

2013-01-01

Structural materials used in engineering applications routinely subjected to repetitive mechanical loads in multiple directions under non-isothermal conditions. Over past few decades, several multiaxial fatigue life estimation models (stress- and strain-based) developed for isothermal conditions. Historically, numerous fatigue life prediction models also developed for thermomechanical fatigue (TMF) life prediction, predominantly for uniaxial mechanical loading conditions. Realistic structural components encounter multiaxial loads and non-isothermal loading conditions, which increase potential for interaction of damage modes. A need exists for mechanical testing and development verification of life prediction models under such conditions.

Mechanics of oriented electrospun nanofibrous scaffolds for annulus fibrosus tissue engineering.

PubMed

Nerurkar, Nandan L; Elliott, Dawn M; Mauck, Robert L

2007-08-01

Engineering a functional replacement for the annulus fibrosus (AF) of the intervertebral disc is contingent upon recapitulation of AF structure, composition, and mechanical properties. In this study, we propose a new paradigm for AF tissue engineering that focuses on the reconstitution of anatomic fiber architecture and uses constitutive modeling to evaluate construct function. A modified electrospinning technique was utilized to generate aligned nanofibrous polymer scaffolds for engineering the basic functional unit of the AF, a single lamella. Scaffolds were tested in uniaxial tension at multiple fiber orientations, demonstrating a nonlinear dependence of modulus on fiber angle that mimicked the nonlinearity and anisotropy of native AF. A homogenization model previously applied to native AF successfully described scaffold mechanical response, and parametric studies demonstrated that nonfibrillar matrix, along with fiber connectivity, are key contributors to tensile mechanics for engineered AF. We demonstrated that AF cells orient themselves along the aligned scaffolds and deposit matrix that contributes to construct mechanics under loading conditions relevant to the in vivo environment. The homogenization model was applied to cell-seeded constructs and provided quantitative measures for the evolution of matrix and interfibrillar interactions. Finally, the model demonstrated that at fiber angles of the AF (28 degrees -44 degrees ), engineered material behaved much like native tissue, suggesting that engineered constructs replicate the physiologic behavior of the single AF lamella. Constitutive modeling provides a powerful tool for analysis of engineered AF neo-tissue and native AF tissue alike, highlighting key mechanical design criteria for functional AF tissue engineering.

Mutagenicity of diesel exhaust particles from an engine with differing exhaust after treatments.

PubMed

Shi, X-C; Keane, M J; Ong, T; Li, S-Q; Bugarski, A B

2010-01-01

This study was conducted to investigate the effects of engine operating conditions and exhaust aftertreatments on the mutagenicity of diesel particulate matter (DPM) collected directly in an underground mine environment. A number of after-treatment devices are currently used on diesel engines in mines, but it is critical to determine whether reductions in DPM concentrations result in a corresponding decrease in adverse health effects. An eddy-current dynamometer was used to operate naturally aspirated mechanically controlled engine at several steady-state conditions. The samples were collected when the engine was equipped with a standard muffler, a diesel oxidation catalytic converter, two types of uncatalyzed diesel particulate filter systems, and three types of disposable diesel particulate filter elements. Bacterial gene mutation activity of DPM was tested on acetone extracts using the Ames Salmonella assay. The results indicated strong correlation between engine operating conditions and mutagenic activity of DPM. When the engine was fitted with muffler, the mutagenic activity was observed for the samples collected from light-load, but not heavy-load operating conditions. When the engine was equipped with a diesel oxidation catalyst, the samples did not exhibit mutagenic activity for any of four engine operating conditions. Mutagenic activity was observed for the samples collected when the engine was retrofitted with three types of disposable filters and sintered metal diesel particulate filter and operated at light load conditions. However, those filtration systems substantially reduced the concentration-normalized mutagenic activity from the levels observed for the muffler.

Finite element study of scaffold architecture design and culture conditions for tissue engineering.

PubMed

Olivares, Andy L; Marsal, Elia; Planell, Josep A; Lacroix, Damien

2009-10-01

Tissue engineering scaffolds provide temporary mechanical support for tissue regeneration and transfer global mechanical load to mechanical stimuli to cells through its architecture. In this study the interactions between scaffold pore morphology, mechanical stimuli developed at the cell microscopic level, and culture conditions applied at the macroscopic scale are studied on two regular scaffold structures. Gyroid and hexagonal scaffolds of 55% and 70% porosity were modeled in a finite element analysis and were submitted to an inlet fluid flow or compressive strain. A mechanoregulation theory based on scaffold shear strain and fluid shear stress was applied for determining the influence of each structures on the mechanical stimuli on initial conditions. Results indicate that the distribution of shear stress induced by fluid perfusion is very dependent on pore distribution within the scaffold. Gyroid architectures provide a better accessibility of the fluid than hexagonal structures. Based on the mechanoregulation theory, the differentiation process in these structures was more sensitive to inlet fluid flow than axial strain of the scaffold. This study provides a computational approach to determine the mechanical stimuli at the cellular level when cells are cultured in a bioreactor and to relate mechanical stimuli with cell differentiation.

Towards an Automated Full-Turbofan Engine Numerical Simulation

NASA Technical Reports Server (NTRS)

Reed, John A.; Turner, Mark G.; Norris, Andrew; Veres, Joseph P.

2003-01-01

The objective of this study was to demonstrate the high-fidelity numerical simulation of a modern high-bypass turbofan engine. The simulation utilizes the Numerical Propulsion System Simulation (NPSS) thermodynamic cycle modeling system coupled to a high-fidelity full-engine model represented by a set of coupled three-dimensional computational fluid dynamic (CFD) component models. Boundary conditions from the balanced, steady-state cycle model are used to define component boundary conditions in the full-engine model. Operating characteristics of the three-dimensional component models are integrated into the cycle model via partial performance maps generated automatically from the CFD flow solutions using one-dimensional meanline turbomachinery programs. This paper reports on the progress made towards the full-engine simulation of the GE90-94B engine, highlighting the generation of the high-pressure compressor partial performance map. The ongoing work will provide a system to evaluate the steady and unsteady aerodynamic and mechanical interactions between engine components at design and off-design operating conditions.

Hybrid computational and experimental approach for the study and optimization of mechanical components

NASA Astrophysics Data System (ADS)

Furlong, Cosme; Pryputniewicz, Ryszard J.

1998-05-01

Increased demands on the performance and efficiency of mechanical components impose challenges on their engineering design and optimization, especially when new and more demanding applications must be developed in relatively short periods of time while satisfying design objectives, as well as cost and manufacturability. In addition, reliability and durability must be taken into consideration. As a consequence, effective quantitative methodologies, computational and experimental, should be applied in the study and optimization of mechanical components. Computational investigations enable parametric studies and the determination of critical engineering design conditions, while experimental investigations, especially those using optical techniques, provide qualitative and quantitative information on the actual response of the structure of interest to the applied load and boundary conditions. We discuss a hybrid experimental and computational approach for investigation and optimization of mechanical components. The approach is based on analytical, computational, and experimental resolutions methodologies in the form of computational, noninvasive optical techniques, and fringe prediction analysis tools. Practical application of the hybrid approach is illustrated with representative examples that demonstrate the viability of the approach as an effective engineering tool for analysis and optimization.

The International Congress of Mechanical Engineering and Agricultural Sciences - CIIMCA 2013

NASA Astrophysics Data System (ADS)

Remolina-Millán, Aduljay; Hernández-Arroyo, Emil

2014-06-01

The organizing committee of The International Congress of Mechanical Engineering and Agricultural Sciences - CIIMCA 2013 - are pleased to present CIIMCA-2013: the first international conference focused on subjects of materials science, mechanical engineering and renewable energy organized by Mechanical Engineering Faculty of the ''Universidad Pontificia Bolivariana'' in Bucaramanga, Colombia. This conference aims to be a place to produce discussions on whole topics of the congress, between the scientists of Colombia and the world. We strongly believe that knowledge is fundamental to the development of our countries. For that reason this multidisciplinary conference is looking forward to integrate engineering, agricultural science and nanoscience and nanotechnology to produce a synergy of this area of knowledge and to achieve scientific and technological developments. Agriculture is a very important topic for our conference; in Colombia, agricultural science needs more attention from the scientific community and the government. In the Faculty of Mechanical Engineering we are beginning to work on these issues to produce knowledge and improve the conditions in our country. The CIIMCA conference is a great opportunity to create interpersonal relationships and networks between scientists around the world. The interaction between scientists is very important in the process of the construction of knowledge. The general chairman encourages and invites you to make friends, relationships and participate strongly in the symposia and all program activities. PhD Aduljay Remolina-Millán Principal Chairman, International Mechanical Engineering and Agricultural Sciences Congress - CIIMCA Msc Emil Hernández-Arroyo Principal Chairman, International Mechanical Engineering and Agricultural Sciences Congress - CIIMCA Conference photograph Conference photograph 'Universidad Pontificia Bolivariana seccional Bucaramanga' host of the first International Mechanical Engineering and Agricultural Sciences Congress - CIIMCA 2013 - Floridablanaca, Colombia. Conference photograph Closure of CIIMCA 2013. Details of the editorial committee and acknowledgements are available in the PDF.

Effects of hydrotreated vegetable oil on emissions of aerosols and gases from light-duty and medium-duty older technology engines.

PubMed

Bugarski, Aleksandar D; Hummer, Jon A; Vanderslice, Shawn

2016-01-01

This study was conducted to assess the potential of hydrotreated vegetable oil renewable diesel (HVORD) as a control strategy to reduce exposure of workers to diesel aerosols and gases. The effects of HVORD on criteria aerosol and gaseous emissions were compared with those of ultralow sulfur diesel (ULSD). The results of comprehensive testing at four steady-state conditions and one transient cycle were used to characterize the aerosol and gaseous emissions from two older technology engines: (1) a naturally aspirated mechanically controlled and (2) a turbocharged electronically controlled engine. Both engines were equipped with diesel oxidation catalytic converters (DOCs). For all test conditions, both engines emitted measurably lower total mass concentrations of diesel aerosols, total carbon, and elemental carbon when HVORD was used in place of ULSD. For all test conditions, the reductions in total mass concentrations were more substantial for the naturally aspirated than for the turbocharged engine. In the case of the naturally aspirated engine, HVORD also favorably affected total surface area of aerosols deposited in the alveolar region of human lungs (TSAADAR) and the total number concentrations of aerosols. In the case of the turbocharged electronically controlled engine, for some of the test conditions HVORD adversely affected the TSAADAR and total number concentrations of aerosols. In the majority of the test cases involving the naturally aspirated mechanically controlled engine, HVORD favorably affected carbon dioxide (CO2), nitrogen oxides (NOX), and nitric oxide (NO) concentrations, but adversely affected NO2 and total hydrocarbon concentrations, while the effects of the fuels on carbon monoxide (CO) concentrations were masked by the effects of DOC. In the case of the turbocharged electronically controlled engine, the CO2, CO, NOX, NO, and total hydrocarbon concentrations were generally lower when HVORD was used in place of ULSD. The effects of the fuels on NO2 concentrations were masked by the more prominent effects of DOC.

Effects of hydrotreated vegetable oil on emissions of aerosols and gases from light-duty andmedium-duty older technology engines

PubMed Central

Bugarski, Aleksandar D.; Hummer, Jon A.; Vanderslice, Shawn

2017-01-01

This study was conducted to assess the potential of hydrotreated vegetable oil renewable diesel (HVORD) as a control strategy to reduce exposure of workers to diesel aerosols and gases. The effects of HVORD on criteria aerosol and gaseous emissions were compared with those of ultralow sulfur diesel (ULSD). The results of comprehensive testing at four steady-state conditions and one transient cycle were used to characterize the aerosol and gaseous emissions from two older technology engines: (1) a naturally aspirated mechanically controlled and (2) a turbocharged electronically controlled engine. Both engines were equipped with diesel oxidation catalytic converters (DOCs). For all test conditions, both engines emitted measurably lower total mass concentrations of diesel aerosols, total carbon, and elemental carbon when HVORD was used in place of ULSD. For all test conditions, the reductions in total mass concentrations were more substantial for the naturally aspirated than for the turbocharged engine. In the case of the naturally aspirated engine, HVORD also favorably affected total surface area of aerosols deposited in the alveolar region of human lungs (TSAADAR) and the total number concentrations of aerosols. In the case of the turbocharged electronically controlled engine, for some of the test conditions HVORD adversely affected the TSAADAR and total number concentrations of aerosols. In the majority of the test cases involving the naturally aspirated mechanically controlled engine, HVORD favorably affected carbon dioxide (CO2), nitrogen oxides (NOX), and nitric oxide (NO) concentrations, but adversely affected NO2 and total hydrocarbon concentrations, while the effects of the fuels on carbon monoxide (CO) concentrations were masked by the effects of DOC. In the case of the turbocharged electronically controlled engine, the CO2, CO, NOX, NO, and total hydrocarbon concentrations were generally lower when HVORD was used in place of ULSD. The effects of the fuels on NO2 concentrations were masked by the more prominent effects of DOC. PMID:26588029

The materials used in bone tissue engineering

NASA Astrophysics Data System (ADS)

Tereshchenko, V. P.; Kirilova, I. A.; Sadovoy, M. A.; Larionov, P. M.

2015-11-01

Bone tissue engineering looking for an alternative solution to the problem of skeletal injuries. The method is based on the creation of tissue engineered bone tissue equivalent with stem cells, osteogenic factors, and scaffolds - the carriers of these cells. For production of tissue engineered bone equivalent is advisable to create scaffolds similar in composition to natural extracellular matrix of the bone. This will provide optimal conditions for the cells, and produce favorable physico-mechanical properties of the final construction. This review article gives an analysis of the most promising materials for the manufacture of cell scaffolds. Biodegradable synthetic polymers are the basis for the scaffold, but it alone cannot provide adequate physical and mechanical properties of the construction, and favorable conditions for the cells. Addition of natural polymers improves the strength characteristics and bioactivity of constructions. Of the inorganic compounds, to create cell scaffolds the most widely used calcium phosphates, which give the structure adequate stiffness and significantly increase its osteoinductive capacity. Signaling molecules do not affect the physico-mechanical properties of the scaffold, but beneficial effect is on the processes of adhesion, proliferation and differentiation of cells. Biodegradation of the materials will help to fulfill the main task of bone tissue engineering - the ability to replace synthetic construct by natural tissues that will restore the original anatomical integrity of the bone.

Influence of engineered interfaces on residual stresses and mechanical response in metal matrix composites

NASA Technical Reports Server (NTRS)

Arnold, Steven M.; Wilt, Thomas E.

1992-01-01

Because of the inherent coefficient of thermal expansion (CTE) mismatch between fiber and matrix within metal and intermetallic matrix composite systems, high residual stresses can develop under various thermal loading conditions. These conditions include cooling from processing temperature to room temperature as well as subsequent thermal cycling. As a result of these stresses, within certain composite systems, radial, circumferential, and/or longitudinal cracks have been observed to form at the fiber matrix interface region. A number of potential solutions for reducing this thermally induced residual stress field have been proposed recently. Examples of some potential solutions are high CTE fibers, fiber preheating, thermal anneal treatments, and an engineered interface. Here the focus is on designing an interface (by using a compensating/compliant layer concept) to reduce or eliminate the thermal residual stress field and, therefore, the initiation and propagation of cracks developed during thermal loading. Furthermore, the impact of the engineered interface on the composite's mechanical response when subjected to isothermal mechanical load histories is examined.

The performance simulation of single cylinder electric power confined piston engine

NASA Astrophysics Data System (ADS)

Gou, Yanan

2017-04-01

A new type of power plant. i.e, Electric Power Confined Piston Engine, is invented by combining the free piston engine and the crank connecting rod mechanism of the traditional internal combustion engine. Directly using the reciprocating movement of the piston, this new engine converts the heat energy produced by fuel to electrical energy and output it. The paper expounds the working mechanism of ECPE and establishes the kinematics and dynamics equations. Furthermore, by using the analytic method, the ECPE electromagnetic force is solved at load cases. Finally, in the simulation environment of MARLAB, the universal characteristic curve is obtained in the condition of rotational speed n between 1000 r/min and 2400 r/min, throttle opening α between 30% and 100%.

Developing Novel Protein-based Materials using Ultrabithorax: Production, Characterization, and Functionalization

NASA Astrophysics Data System (ADS)

Huang, Zhao

2011-12-01

Compared to 'conventional' materials made from metal, glass, or ceramics, protein-based materials have unique mechanical properties. Furthermore, the morphology, mechanical properties, and functionality of protein-based materials may be optimized via sequence engineering for use in a variety of applications, including textile materials, biosensors, and tissue engineering scaffolds. The development of recombinant DNA technology has enabled the production and engineering of protein-based materials ex vivo. However, harsh production conditions can compromise the mechanical properties of protein-based materials and diminish their ability to incorporate functional proteins. Developing a new generation of protein-based materials is crucial to (i) improve materials assembly conditions, (ii) create novel mechanical properties, and (iii) expand the capacity to carry functional protein/peptide sequences. This thesis describes development of novel protein-based materials using Ultrabithorax, a member of the Hox family of proteins that regulate developmental pathways in Drosophila melanogaster. The experiments presented (i) establish the conditions required for the assembly of Ubx-based materials, (ii) generate a wide range of Ubx morphologies, (iii) examine the mechanical properties of Ubx fibers, (iv) incorporate protein functions to Ubx-based materials via gene fusion, (v) pattern protein functions within the Ubx materials, and (vi) examine the biocompatibility of Ubx materials in vitro. Ubx-based materials assemble at mild conditions compatible with protein folding and activity, which enables Ubx chimeric materials to retain the function of appended proteins in spatial patterns determined by materials assembly. Ubx-based materials also display mechanical properties comparable to existing protein-based materials and demonstrate good biocompatibility with living cells in vitro. Taken together, this research demonstrates the unique features and future potential of novel Ubx-based materials.

Characteristics and engineering properties of the soft soil layer in highway soil subgrades.

DOT National Transportation Integrated Search

2006-06-01

The objective of this research was to examine the conditions and characteristics of soil subgrades that had been stabilized using mechanical compaction. Goals of the study are to identify and examine the engineering properties and behavior of the ...

Strain response of thermal barrier coatings captured under extreme engine environments through synchrotron X-ray diffraction

NASA Astrophysics Data System (ADS)

Knipe, Kevin; Manero, Albert; Siddiqui, Sanna F.; Meid, Carla; Wischek, Janine; Okasinski, John; Almer, Jonathan; Karlsson, Anette M.; Bartsch, Marion; Raghavan, Seetha

2014-07-01

The mechanical behaviour of thermal barrier coatings in operation holds the key to understanding durability of jet engine turbine blades. Here we report the results from experiments that monitor strains in the layers of a coating subjected to thermal gradients and mechanical loads representing extreme engine environments. Hollow cylindrical specimens, with electron beam physical vapour deposited coatings, were tested with internal cooling and external heating under various controlled conditions. High-energy synchrotron X-ray measurements captured the in situ strain response through the depth of each layer, revealing the link between these conditions and the evolution of local strains. Results of this study demonstrate that variations in these conditions create corresponding trends in depth-resolved strains with the largest effects displayed at or near the interface with the bond coat. With larger temperature drops across the coating, significant strain gradients are seen, which can contribute to failure modes occurring within the layer adjacent to the interface.

Technical Support. Focus on Careers.

ERIC Educational Resources Information Center

Thiers, Naomi

1996-01-01

Describes work conditions, education and training needs, and salaries of the following technician careers: auto/diesel technicians, auto body repairers, general maintenance mechanics, heating/air conditioning/refrigeration, paralegals, engineering technicians, science technicians, computer repairers, and drafters. (SK)

Is the 2nd Law of Thermodynamics Conditioned? Separating Heat and Cold by a Magnetic Body Force and the Principle for a Non-Carnot Engine

NASA Astrophysics Data System (ADS)

Luo, Weili

2017-11-01

A new type of heat engine has been proposed in 2005 that defies fundamental thermodynamic law: A specifically designed magnetic body force can reverse heat flow from high temperature to low temperature. This mechanism can drive heat to higher temperature, rendering the possibility to re-use the ``waste heat''. As the result, the efficiency is much higher than that of the Carnot Engine. In a recent paper a realization of this proposed mechanism is reported: by using a specific configuration of temperature and magnetic field gradients, we observed that magnetic body force suppresses the gravito-thermal convective heat when the gradients of temperature and field are anti-parallel to each other. This driving force stops the heat flow of approaching to thermal equilibrium in the system, causing the temperature difference across the sample to increase with applied fields. In this work, I will discuss the driving mechanism for this phenomenon and its application in the proposed engine. This remarkable result suggests that the 2nd law of thermodynamics maybe conditioned and needs to be re-examined.

Development of Mechanics in Support of Rocket Technology in Ukraine

NASA Astrophysics Data System (ADS)

Prisnyakov, Vladimir

2003-06-01

The paper analyzes the advances of mechanics made in Ukraine in resolving various problems of space and rocket technology such as dynamics and strength of rockets and rocket engines, rockets of different purpose, electric rocket engines, and nonstationary processes in various systems of rockets accompanied by phase transitions of working media. Achievements in research on the effect of vibrations and gravitational fields on the behavior of space-rocket systems are also addressed. Results obtained in investigating the reliability and structural strength durability conditions for nuclear installations, solid- and liquid-propellant engines, and heat pipes are presented

Impact of air conditioning system operation on increasing gases emissions from automobile

NASA Astrophysics Data System (ADS)

Burciu, S. M.; Coman, G.

2016-08-01

The paper presents a study concerning the influence of air conditioning system operation on the increase of gases emissions from cars. The study focuses on urban operating regimes of the automobile, regimes when the engines have low loads or are operating at idling. Are presented graphically the variations of pollution emissions (CO, CO2, HC) depending of engine speed and the load on air conditioning system. Additionally are presented, injection duration, throttle position, the mechanical power required by the compressor of air conditioning system and the refrigerant pressure variation on the discharge path, according to the stage of charging of the air conditioning system.

Effect of ambient conditions on the emissions from a gas turbine combustor

NASA Technical Reports Server (NTRS)

Kauffman, C. W.

1980-01-01

The effect of variations in the ambient conditions of pressure, temperature, and relative humidity upon the emissions of a gas turbine combustion are investigated. A single combustor can from a Pratt and Whitney JT8D-17 engine was run at parametric inlet conditions bracketing the actual engine idle conditions. Data were correlated to determine the functional relationships between the emissions and ambient conditions. Mathematical modelling was used to determine the mechanism for the carbon monoxide and hydrocarbon emissions. Carbon monoxide emissions were modelled using finite rate chemical kinetics in a plug flow scheme. Hydrocarbon emissions were modelled by a vaporization scheme throughout the combustor.

Maintenance of Mechanical Equipment in Minnesota Schools, 1968 Survey.

ERIC Educational Resources Information Center

Larson, R. E.; Rust, L. W.

Results of a one-year research program to study maintenance procedures for operating mechanical equipment were based on the determination of--(1) the present condition and level of performance of operating mechanical equipment, (2) the problems encountered by school administrators and custodial engineers pertaining to operating mechanical…

Thermo-mechanical concepts applied to modeling liquid propellant rocket engine stability

NASA Astrophysics Data System (ADS)

Kassoy, David R.; Norris, Adam

2016-11-01

The response of a gas to transient, spatially distributed energy addition can be quantified mathematically using thermo-mechanical concepts available in the literature. The modeling demonstrates that the ratio of the energy addition time scale to the acoustic time scale of the affected volume, and the quantity of energy added to that volume during the former determine the whether the responses to heating can be described as occurring at nearly constant volume, fully compressible or nearly constant pressure. Each of these categories is characterized by significantly different mechanical responses. Application to idealized configurations of liquid propellant rocket engines provides an opportunity to identify physical conditions compatible with gasdynamic disturbances that are sources of engine instability. Air Force Office of Scientific Research.

Electric turbocompound control system

DOEpatents

Algrain, Marcelo C [Dunlap, IL

2007-02-13

Turbocompound systems can be used to affect engine operation using the energy in exhaust gas that is driving the available turbocharger. A first electrical device acts as a generator in response to turbocharger rotation. A second electrical device acts as a motor to put mechanical power into the engine, typically at the crankshaft. Apparatus, systems, steps, and methods are described to control the generator and motor operations to control the amount of power being recovered. This can control engine operation closer to desirable parameters for given engine-related operating conditions compared to actual. The electrical devices can also operate in "reverse," going between motor and generator functions. This permits the electrical device associated with the crankshaft to drive the electrical device associated with the turbocharger as a motor, overcoming deficient engine operating conditions such as associated with turbocharger lag.

HPAC Info-dex 5: Locating engineering societies, associations

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-06-01

This is the 1995/1996 listing of heating, ventilation, air conditioning and refrigeration systems engineering societies, trade associations, and government organizations that have established performance standards for mechanical systems and components. The societies and associations are listed alphabetically along with their complete addresses and telephone and FAX numbers.

The materials used in bone tissue engineering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tereshchenko, V. P., E-mail: tervp@ngs.ru; Kirilova, I. A.; Sadovoy, M. A.

Bone tissue engineering looking for an alternative solution to the problem of skeletal injuries. The method is based on the creation of tissue engineered bone tissue equivalent with stem cells, osteogenic factors, and scaffolds - the carriers of these cells. For production of tissue engineered bone equivalent is advisable to create scaffolds similar in composition to natural extracellular matrix of the bone. This will provide optimal conditions for the cells, and produce favorable physico-mechanical properties of the final construction. This review article gives an analysis of the most promising materials for the manufacture of cell scaffolds. Biodegradable synthetic polymers aremore » the basis for the scaffold, but it alone cannot provide adequate physical and mechanical properties of the construction, and favorable conditions for the cells. Addition of natural polymers improves the strength characteristics and bioactivity of constructions. Of the inorganic compounds, to create cell scaffolds the most widely used calcium phosphates, which give the structure adequate stiffness and significantly increase its osteoinductive capacity. Signaling molecules do not affect the physico-mechanical properties of the scaffold, but beneficial effect is on the processes of adhesion, proliferation and differentiation of cells. Biodegradation of the materials will help to fulfill the main task of bone tissue engineering - the ability to replace synthetic construct by natural tissues that will restore the original anatomical integrity of the bone.« less

Asbestos exposure from gaskets during disassembly of a medium duty diesel engine.

PubMed

Liukonen, Larry R; Weir, Francis W

2005-03-01

Diesel engines have historically used asbestos-containing gaskets leading to concerns of fiber release and mechanic exposure. Other published studies regarding asbestos fiber release during gasket removal have reported on short-duration events; were conducted under simulated work conditions; or had other limitations. There are no comprehensive studies relating to diesel engine gaskets under conditions similar to those reported herein, evaluating asbestos fiber release from gaskets during all facets of a complete disassembly and cleaning of a medium duty diesel engine in a busy repair and service shop by a journeyman mechanic. Asbestos content of all gaskets was identified; all disassembly tasks were described and timed; and personal and area air monitoring was conducted for each task. Twenty seven of thirty three gaskets contained chrysotile asbestos in concentrations that ranged from 5 to 70%. All but one air monitoring sample reported results below the limit of reliable detection even though plumes of visible dust were evident during various removal, cleaning, and buffing procedures. The detection limit for airborne asbestos fibers in this investigation was influenced by the presence of other shop dust in the air. Our investigation demonstrates that using shop-standard procedures in an established repair facility, a journeyman mechanic has very little potential for exposure to airborne asbestos fibers during disassembly of an engine, approximately 10% or less than that currently considered to be acceptable by OSHA.

Elastase-Sensitive Elastomeric Scaffolds with Variable Anisotropy for Soft Tissue Engineering

PubMed Central

Guan, Jianjun; Fujimoto, Kazuro L.; Wagner, William R.

2010-01-01

Purpose To develop elastase-sensitive polyurethane scaffolds that would be applicable to the engineering of mechanically active soft tissues. Methods A polyurethane containing an elastase-sensitive peptide sequence was processed into scaffolds by thermally induced phase separation. Processing conditions were manipulated to alter scaffold properties and anisotropy. The scaffold’s mechanical properties, degradation, and cytocompatibility using muscle-derived stem cells were characterized. Scaffold in vivo degradation was evaluated by subcutaneous implantation. Results When heat transfer was multidirectional, scaffolds had randomly oriented pores. Imposition of a heat transfer gradient resulted in oriented pores. Both scaffolds were flexible and relatively strong with mechanical properties dependent upon fabrication conditions such as solvent type, polymer concentration and quenching temperature. Oriented scaffolds exhibited anisotropic mechanical properties with greater tensile strength in the orientation direction. These scaffolds also supported muscle-derived stem cell growth more effectively than random scaffolds. The scaffolds expressed over 40% weight loss after 56 days in elastase containing buffer. Elastase-sensitive scaffolds were complete degraded after 8 weeks subcutaneous implantation in rats, markedly faster than similar polyurethanes that did not contain the peptide sequence. Conclusion The elastase-sensitive polyurethane scaffolds showed promise for application in soft tissue engineering where controlling scaffold mechanical properties and pore architecture are desirable. PMID:18509596

Effects of Structural Deformations of the Crank-Slider Mechanism on the Estimation of the Instantaneous Engine Friction Torque

NASA Astrophysics Data System (ADS)

CHALHOUB, N. G.; NEHME, H.; HENEIN, N. A.; BRYZIK, W.

1999-07-01

The focus on the current study is to assess the effects of structural deformations of the crankshaft/connecting-rod/piston mechanism on the computation of the instantaneous engine friction torque. This study is performed in a fully controlled environment in order to isolate the effects of structural deformations from those of measurement errors or noise interference. Therefore, a detailed model, accounting for the rigid and flexible motions of the crank-slider mechanism and including engine component friction formulations, is considered in this study. The model is used as a test bed to generate the engine friction torque,Tfa, and to predict the rigid and flexible motions of the system in response to the cylinder gas pressure. The torsional vibrations and the rigid body angular velocity of the crankshaft, as predicted by the detailed model of the crank-slider mechanism, are used along with the engine load torque and the cylinder gas pressure in the (P-ω) method to estimate the engine friction torque,Tfe. This method is well suited for the purpose of this study because its formulation is based on the rigid body model of the crank-slider mechanism. The digital simulation results demonstrate that the exclusion of the structural deformations of the crank-slider mechanism from the formulation of the (P-ω) method leads to an overestimation of the engine friction torque near the top-dead-center (TDC) position of the piston under firing conditions. Moreover, for the remainder of the engine cycle, the estimated friction torque exhibits large oscillations and takes on positive numerical values as if it is inducing energy into the system. Thus, the adverse effects of structural deformations of the crank-slider mechanism on the estimation of the engine friction torque greatly differ in their nature from one phase of the engine cycle to another.

Effects of a Pseudophysiological Environment on the Elastic and Viscoelastic Properties of Collagen Gels

PubMed Central

Meghezi, Sébastien; Couet, Frédéric; Chevallier, Pascale; Mantovani, Diego

2012-01-01

Vascular tissue engineering focuses on the replacement of diseased small-diameter blood vessels with a diameter less than 6 mm for which adequate substitutes still do not exist. One approach to vascular tissue engineering is to culture vascular cells on a scaffold in a bioreactor. The bioreactor establishes pseudophysiological conditions for culture (medium culture, 37°C, mechanical stimulation). Collagen gels are widely used as scaffolds for tissue regeneration due to their biological properties; however, they exhibit low mechanical properties. Mechanical characterization of these scaffolds requires establishing the conditions of testing in regard to the conditions set in the bioreactor. The effects of different parameters used during mechanical testing on the collagen gels were evaluated in terms of mechanical and viscoelastic properties. Thus, a factorial experiment was adopted, and three relevant factors were considered: temperature (23°C or 37°C), hydration (aqueous saline solution or air), and mechanical preconditioning (with or without). Statistical analyses showed significant effects of these factors on the mechanical properties which were assessed by tensile tests as well as stress relaxation tests. The last tests provide a more consistent understanding of the gels' viscoelastic properties. Therefore, performing mechanical analyses on hydrogels requires setting an adequate environment in terms of temperature and aqueous saline solution as well as choosing the adequate test. PMID:22844285

Thermal-structural analyses of Space Shuttle Main Engine (SSME) hot section components

NASA Technical Reports Server (NTRS)

Abdul-Aziz, Ali; Thompson, Robert L.

1988-01-01

Three dimensional nonlinear finite element heat transfer and structural analyses were performed for the first stage high pressure fuel turbopump (HPFTP) blade of the space shuttle main engine (SSME). Directionally solidified (DS) MAR-M 246 and single crystal (SC) PWA-1480 material properties were used for the analyses. Analytical conditions were based on a typical test stand engine cycle. Blade temperature and stress strain histories were calculated by using the MARC finite element computer code. The structural response of an SSME turbine blade was assessed and a greater understanding of blade damage mechanisms, convective cooling effects, and thermal mechanical effects was gained.

Ionic Mechanisms of Carbon Formation in Flames.

DTIC Science & Technology

1981-05-01

EFFECT OF MOLECULAR STRUCTURE ON INCIPIENT SOOT FORMATION, H.F. Calcote and D.M. Manos APPENDIX E: CORRELATION OF SOOT FORMATION IN TURBOJET ENGINES...future use by the Air Force of synfuels derived from coal, tar sands, and shale oil . These fuels are expected to have higher molecular weights, more...emissions and flame radiation from turbojet engines and larger scale combustors simulating practical engine conditions. b. Interpret and correlate the

Effect of Maximum Cruise-power Operation at Ultra-lean Mixture and Increased Spark Advance on the Mechanical Condition of Cylinder Components

NASA Technical Reports Server (NTRS)

Harris, Herbert B.; Duffy, Robert T.; Erwin, Robert D., Jr.

1945-01-01

A continuous 50-hour test was conducted to determine the effect of maximum cruise-power operation at ultra-lean fuel-air mixture and increased spark advance on the mechanical conditions of cylinder components. The test was conducted on a nine-cylinder air-cooled radial engine at the following conditions:brake horsepower, 750; engine speed, 1900 rpm; brake mean effective pressure, 172 pounds per square inch; fuel-air ratio, 0.052; spark advance, 30 deg B.T.C.; and maximum rear-spark-plug-bushing temperature, 400 F. In addition to the data on corrosion and wear, data are presented and briefly discussed on the effect of engine operation at the conditions of this test on economy, knock, preignition, and mixture distribution. Cylinder, piston, and piston-ring wear was small and all cylinder component were in good condition at the conclusion of the 50-hour test except that all exhaust-valve guides were bellmouthed beyond the Army's specified limit and one exhaust-valve face was lightly burned. It is improbable that the light burning in one spot of the valve face would have progressed further because the burn was filled with a hard deposit so that the valve face formed an unbroken seal and the mating seat showed no evidence of burning. The bellmouthing of the exhaust-valve guides is believed to have been a result of the heavy carbon and lead-oxide deposits, which were present on the head end of the guided length of the exhaust-valve stem. Engine operational the conditions of this test was shown to result In a fuel saving of 16.8 percent on a cooled-power basis as compared with operation at the conditions recommended for this engine by the Army Air Forces for the same power.

Dental pulp stem cells express tendon markers under mechanical loading and are a potential cell source for tissue engineering of tendon-like tissue.

PubMed

Chen, Yu-Ying; He, Sheng-Teng; Yan, Fu-Hua; Zhou, Peng-Fei; Luo, Kai; Zhang, Yan-Ding; Xiao, Yin; Lin, Min-Kui

2016-12-16

Postnatal mesenchymal stem cells have the capacity to differentiate into multiple cell lineages. This study explored the possibility of dental pulp stem cells (DPSCs) for potential application in tendon tissue engineering. The expression of tendon-related markers such as scleraxis, tenascin-C, tenomodulin, eye absent homologue 2, collagens I and VI was detected in dental pulp tissue. Interestingly, under mechanical stimulation, these tendon-related markers were significantly enhanced when DPSCs were seeded in aligned polyglycolic acid (PGA) fibre scaffolds. Furthermore, mature tendon-like tissue was formed after transplantation of DPSC-PGA constructs under mechanical loading conditions in a mouse model. This study demonstrates that DPSCs could be a potential stem cell source for tissue engineering of tendon-like tissue.

Large Eddy Simulation of Turbulent Combustion

DTIC Science & Technology

2006-03-15

described accurately by the skeletal mechanism , usually the major reactants and products, NO and NO2 if we are interested in NOx formation, and any...LARGE EDDY SIMULATION OF TURBULENT COMBUSTION Principle Investigator: Heinz Pitsch Flow Physics and Computation Department of Mechanical Engineering ...are identified. These de- tailed mechanisms are reduced independently for various conditions and accuracy requirements. The skeletal mechanisms form

Mechanism of plasma-assisted ignition for H2 and C1-C5 hydrocarbons

NASA Astrophysics Data System (ADS)

Starikovskiy, Andrey; Aleksandrov, Nikolay

2016-09-01

Nonequilibrium plasma demonstrates ability to control ultra-lean, ultra-fast, low-temperature flames and appears to be an extremely promising technology for a wide range of applications, including aviation GTEs, piston engines, ramjets, scramjets and detonation initiation for pulsed detonation engines. To use nonequilibrium plasma for ignition and combustion in real energetic systems, one must understand the mechanisms of plasma-assisted ignition and combustion and be able to numerically simulate the discharge and combustion processes under various conditions. A new, validated mechanism for high-temperature hydrocarbon plasma assisted combustion was built and allows to qualitatively describe plasma-assisted combustion close and above the self-ignition threshold. The principal mechanisms of plasma-assisted ignition and combustion have been established and validated for a wide range of plasma and gas parameters. These results provide a basis for improving various energy-conversion combustion systems, from automobile to aircraft engines, using nonequilibrium plasma methods.

Environmental Barrier Coating Fracture, Fatigue and High-Heat-Flux Durability Modeling and Stochastic Progressive Damage Simulation

NASA Technical Reports Server (NTRS)

Zhu, Dongming; Nemeth, Noel N.

2017-01-01

Advanced environmental barrier coatings will play an increasingly important role in future gas turbine engines because of their ability to protect emerging light-weight SiC/SiC ceramic matrix composite (CMC) engine components, further raising engine operating temperatures and performance. Because the environmental barrier coating systems are critical to the performance, reliability and durability of these hot-section ceramic engine components, a prime-reliant coating system along with established life design methodology are required for the hot-section ceramic component insertion into engine service. In this paper, we have first summarized some observations of high temperature, high-heat-flux environmental degradation and failure mechanisms of environmental barrier coating systems in laboratory simulated engine environment tests. In particular, the coating surface cracking morphologies and associated subsequent delamination mechanisms under the engine level high-heat-flux, combustion steam, and mechanical creep and fatigue loading conditions will be discussed. The EBC compostion and archtechture improvements based on advanced high heat flux environmental testing, and the modeling advances based on the integrated Finite Element Analysis Micromechanics Analysis Code/Ceramics Analysis and Reliability Evaluation of Structures (FEAMAC/CARES) program will also be highlighted. The stochastic progressive damage simulation successfully predicts mud flat damage pattern in EBCs on coated 3-D specimens, and a 2-D model of through-the-thickness cross-section. A 2-parameter Weibull distribution was assumed in characterizing the coating layer stochastic strength response and the formation of damage was therefore modeled. The damage initiation and coalescence into progressively smaller mudflat crack cells was demonstrated. A coating life prediction framework may be realized by examining the surface crack initiation and delamination propagation in conjunction with environmental degradation under high-heat-flux and environment load test conditions.

MECHANICAL STRENGTH RESPONSES OF POLED LEAD ZIRCONATE TITANATE UNDER EXTREME ELECTRIC FIELD AND VARIOUS TEMPERATURE CONDITIONS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Hong; Matsunaga, Tadashi; Zhang, Kewei

PZT (lead zirconate titanate), particularly PZT-5A, is used in a variety of critical actuation and sensing systems because of its high Curie temperature and large piezoelectric coefficients. However, PZT is susceptible to mechanical failure. The evaluation of the mechanical strength of the material under the target working conditions is very important. This study presents part of the recent experimental developments in mechanical testing and evaluation of PZT materials at Oak Ridge National Laboratory. Ball-on-ring and four-point bending testing setups were used, with modifications made to account for testing requirements from high-level electric field and elevated temperature. The poled PZT-5A ormore » equivalent material was tested under various specimen and testing conditions. The parameters of the distribution of strengths (characteristic strength and Weibull modulus) are discussed in relation to the testing conditions. Fractographic results based on scanning electron microscopy are also presented and discussed. The related data can serve as input for the design of piezoceramic devices, not only those used in energy systems like fuel injectors in heavy-duty diesel engines, but also those used in structural health monitoring, energy harvesting, and other critical systems in aerospace and civil engineering.« less

A comprehensive combustion model for biodiesel-fueled engine simulations

NASA Astrophysics Data System (ADS)

Brakora, Jessica L.

Engine models for alternative fuels are available, but few are comprehensive, well-validated models that include accurate physical property data as well as a detailed description of the fuel chemistry. In this work, a comprehensive biodiesel combustion model was created for use in multi-dimensional engine simulations, specifically the KIVA3v R2 code. The model incorporates realistic physical properties in a vaporization model developed for multi-component fuel sprays and applies an improved mechanism for biodiesel combustion chemistry. A reduced mechanism was generated from the methyl decanoate (MD) and methyl-9-decenoate (MD9D) mechanism developed at Lawrence Livermore National Laboratory. It was combined with a multi-component mechanism to include n-heptane in the fuel chemistry. The biodiesel chemistry was represented using a combination of MD, MD9D and n-heptane, which varied for a given fuel source. The reduced mechanism, which contained 63 species, accurately predicted ignition delay times of the detailed mechanism over a range of engine-specific operating conditions. Physical property data for the five methyl ester components of biodiesel were added to the KIVA library. Spray simulations were performed to ensure that the models adequately reproduce liquid penetration observed in biodiesel spray experiments. Fuel composition impacted liquid length as expected, with saturated species vaporizing more and penetrating less. Distillation curves were created to ensure the fuel vaporization process was comparable to available data. Engine validation was performed against a low-speed, high-load, conventional combustion experiments and the model was able to predict the performance and NOx formation seen in the experiment. High-speed, low-load, low-temperature combustion conditions were also modeled, and the emissions (HC, CO, NOx) and fuel consumption were well-predicted for a sweep of injection timings. Finally, comparisons were made between the results of biodiesel composition (palm vs. soy) and fuel blends (neat vs. B20). The model effectively reproduced the trends observed in the experiments.

Influence analysis of electronically and vibrationally excited particles on the ignition of methane and hydrogen under the conditions of a gas turbine engine

NASA Astrophysics Data System (ADS)

Deminskii, M. A.; Konina, K. M.; Potapkin, B. V.

2018-03-01

The vibronic and electronic energy relaxation phenomena in the specific conditions of a gas turbine engine were investigated in this paper. The plasma-chemical mechanism has been augmented with the results of recent investigations of the processes that involve electronically and vibrationally excited species. The updated mechanism was employed for the computer simulation of plasma-assisted combustion of hydrogen-air and methane-air mixtures under high pressure and in the range of initial temperatures T  =  500-900 K. The updated mechanism was verified using the experimental data. The influence of electronically excited nitrogen on the ignition delay time was analyzed. The rate coefficient of the vibration-vibration exchange between N2 and HO2 was calculated as well as the rate coefficient of HO2 decomposition.

Multi-scale mechanical response of freeze-dried collagen scaffolds for tissue engineering applications.

PubMed

Offeddu, Giovanni S; Ashworth, Jennifer C; Cameron, Ruth E; Oyen, Michelle L

2015-02-01

Tissue engineering has grown in the past two decades as a promising solution to unresolved clinical problems such as osteoarthritis. The mechanical response of tissue engineering scaffolds is one of the factors determining their use in applications such as cartilage and bone repair. The relationship between the structural and intrinsic mechanical properties of the scaffolds was the object of this study, with the ultimate aim of understanding the stiffness of the substrate that adhered cells experience, and its link to the bulk mechanical properties. Freeze-dried type I collagen porous scaffolds made with varying slurry concentrations and pore sizes were tested in a viscoelastic framework by macroindentation. Membranes made up of stacks of pore walls were indented using colloidal probe atomic force microscopy. It was found that the bulk scaffold mechanical response varied with collagen concentration in the slurry consistent with previous studies on these materials. Hydration of the scaffolds resulted in a more compliant response, yet lesser viscoelastic relaxation. Indentation of the membranes suggested that the material making up the pore walls remains unchanged between conditions, so that the stiffness of the scaffolds at the scale of seeded cells is unchanged; rather, it is suggested that thicker pore walls or more of these result in the increased moduli for the greater slurry concentration conditions. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

Investigation of Deposit Formation Mechanisms for Engine In-cylinder Combustion and Exhaust Systems Using Quantitative Analysis and Sustainability Study

NASA Astrophysics Data System (ADS)

Ye, Z.; Meng, Q.; Mohamadian, H. P.; Wang, J. T.; Chen, L.; Zhu, L.

2007-06-01

The formation of SI engine combustion deposits is a complex phenomenon which depends on various factors of fuel, oil, additives, and engine. The goal of this study is to examine the effects of operating conditions, gasoline, lubricating oil, and additives on deposit formation. Both an experimental investigation and theoretical analysis are conducted on a single cylinder engine. As a result, the impact of deposits on engine performance and exhaust emissions (HC, NO x ) has been indicated. Using samples from a cylinder head and exhaust pipe as well as switching gases via the dual-gas method (N2, O2), the deposit formation mechanism is thoroughly investigated via the thermogravity analysis approach, where the roles of organic, inorganic, and volatile components of fuel, additives, and oil on deposit formation are identified from thermogravity curves. Sustainable feedback control design is then proposed for potential emission control and performance optimization

Tissue-engineered vascular grafts composed of marine collagen and PLGA fibers using pulsatile perfusion bioreactors.

PubMed

Jeong, Sung In; Kim, So Yeon; Cho, Seong Kwan; Chong, Moo Sang; Kim, Kyung Soo; Kim, Hyuck; Lee, Sang Bong; Lee, Young Moo

2007-02-01

Novel tubular scaffolds of marine source collagen and PLGA fibers were fabricated by freeze drying and electrospinning processes for vascular grafts. The hybrid scaffolds, composed of a porous collagen matrix and a fibrous PLGA layer, had an average pore size of 150+/-50 microm. The electrospun fibrous PLGA layer on the surface of a porous tubular collagen scaffold improved the mechanical strength of the collagen scaffolds in both the dry and wet states. Smooth muscle cells (SMCs)- and endothelial cells (ECs)-cultured collagen/PLGA scaffolds exhibited mechanical properties similar to collagen/PLGA scaffolds unseeded with cells, even after culturing for 23 days. The effect of a mechanical stimulation on the proliferation and phenotype of SMCs and ECs, cultured on collagen/PLGA scaffolds, was evaluated. The pulsatile perfusion system enhanced the SMCs and ECs proliferation. In addition, a significant cell alignment in a direction radial to the distending direction was observed in tissues exposed to radial distention, which is similar to the phenomenon of native vessel tissues in vivo. On the other hand, cells in tissues engineered in the static condition were randomly aligned. Immunochemical analyses showed that the expressions of SM alpha-actin, SM myosin heavy chain, EC von Willebrand factor, and EC nitric oxide were upregulated in tissues engineered under a mechano-active condition, compared to vessel tissues engineered in the static condition. These results indicated that the co-culturing of SMCs and ECs, using collagen/PLGA hybrid scaffolds under a pulsatile perfusion system, leads to the enhancement of vascular EC development, as well as the retention of the differentiated cell phenotype.

Influence of the mechanical environment on the engineering of mineralised tissues using human dental pulp stem cells and silk fibroin scaffolds.

PubMed

Woloszyk, Anna; Holsten Dircksen, Sabrina; Bostanci, Nagihan; Müller, Ralph; Hofmann, Sandra; Mitsiadis, Thimios A

2014-01-01

Teeth constitute a promising source of stem cells that can be used for tissue engineering and regenerative medicine purposes. Bone loss in the craniofacial complex due to pathological conditions and severe injuries could be treated with new materials combined with human dental pulp stem cells (hDPSCs) that have the same embryonic origin as craniofacial bones. Optimising combinations of scaffolds, cells, growth factors and culture conditions still remains a great challenge. In the present study, we evaluate the mineralisation potential of hDPSCs seeded on porous silk fibroin scaffolds in a mechanically dynamic environment provided by spinner flask bioreactors. Cell-seeded scaffolds were cultured in either standard or osteogenic media in both static and dynamic conditions for 47 days. Histological analysis and micro-computed tomography of the samples showed low levels of mineralisation when samples were cultured in static conditions (0.16±0.1 BV/TV%), while their culture in a dynamic environment with osteogenic medium and weekly µCT scans (4.9±1.6 BV/TV%) significantly increased the formation of homogeneously mineralised structures, which was also confirmed by the elevated calcium levels (4.5±1.0 vs. 8.8±1.7 mg/mL). Molecular analysis of the samples showed that the expression of tooth correlated genes such as Dentin Sialophosphoprotein and Nestin were downregulated by a factor of 6.7 and 7.4, respectively, in hDPSCs when cultured in presence of osteogenic medium. This finding indicates that hDPSCs are able to adopt a non-dental identity by changing the culture conditions only. Also an increased expression of Osteocalcin (1.4x) and Collagen type I (1.7x) was found after culture under mechanically dynamic conditions in control medium. In conclusion, the combination of hDPSCs and silk scaffolds cultured under mechanical loading in spinner flask bioreactors could offer a novel and promising approach for bone tissue engineering where appropriate and rapid bone regeneration in mechanically loaded tissues is required.

On the dynamical vs. thermodynamical performance of a β-type Stirling engine

NASA Astrophysics Data System (ADS)

Reséndiz-Antonio, Margarita; Santillán, Moisés

2014-09-01

In this work we present a simple mathematical model for a β-type Stirling engine. Despite its simplicity, the model considers all the engine’s relevant thermodynamic and mechanical aspects. The dynamic behavior of the model equation of motion is analyzed in order to obtain the sufficient conditions for engine cycling and to study the stability of the stationary regime. The performance of the engine’s thermodynamic part is also investigated. As a matter of fact, we found that it corresponds to a Carnot engine.

Advanced Environmental Barrier Coating and SA Tyrannohex SiC Composites Integration for Improved Thermomechanical and Environmental Durability

NASA Technical Reports Server (NTRS)

Zhu, Dongming; Halbig, Michael; Singh, Mrityunjay

2018-01-01

The development of 2700 degF capable environmental barrier coating (EBC) systems, particularly, the Rare Earth "Hafnium" Silicon bond coat systems, have significantly improved the temperature capability and environmental stability of SiC/SiC Ceramic Matrix Composite Systems. We have specifically developed the advanced 2700 degF EBC systems, integrating the EBC to the high temperature SA Tyrannohex SiC fiber composites, for comprehensive performance and durability evaluations for potential turbine engine airfoil component applications. The fundamental mechanical properties, environmental stability and thermal gradient cyclic durability performance of the EBC - SA Tyrannohex composites were investigated. The paper will particularly emphasize the high pressure combustion rig recession, cyclic thermal stress resistance and thermomechanical low cycle fatigue testing of uncoated and environmental barrier coated Tyrannohex SiC SA composites in these simulated turbine engine combustion water vapor, thermal gradients, and mechanical loading conditions. We have also investigated high heat flux and flexural fatigue degradation mechanisms, determined the upper limits of operating temperature conditions for the coated SA composite material systems in thermomechanical fatigue conditions. Recent progress has also been made by using the self-healing rare earth-silicon based EBCs, thus enhancing the SA composite hexagonal fiber columns bonding for improved thermomechanical and environmental durability in turbine engine operation environments. More advanced EBC- composite systems based on the new EBC-Fiber Interphases will also be discussed.

Degradation Mechanisms of an Advanced Jet Engine Service-Retired TBC Component

NASA Astrophysics Data System (ADS)

Wu, Rudder T.; Osawa, Makoto; Yokokawa, Tadaharu; Kawagishi, Kyoko; Harada, Hiroshi

Current use of TBCs is subjected to premature spallation failure mainly due to the formation of thermally grown oxides (TGOs). Although extensive research has been carried out to gain better understanding of the thermo - mechanical and -chemical characteristics of TBCs, laboratory-scale studies and simulation tests are often carried out in conditions significantly differed from the complex and extreme environment typically of a modern gas-turbine engine, thus, failed to truly model service conditions. In particular, the difference in oxygen partial pressure and the effects of contaminants present in the engine compartment have often been neglected. In this respect, an investigation is carried out to study the in-service degradation of an EB-PVD TBC coated nozzle-guide vane. Several modes of degradation were observed due to three factors: 1) presence of residual stresses induced by the thermal-expansion mismatches, 2) evolution of bond coat microstructure and subsequent formation of oxide spinels, 3) deposition of CMAS on the surface of TBC.

Acceleration of the chemistry solver for modeling DI engine combustion using dynamic adaptive chemistry (DAC) schemes

NASA Astrophysics Data System (ADS)

Shi, Yu; Liang, Long; Ge, Hai-Wen; Reitz, Rolf D.

2010-03-01

Acceleration of the chemistry solver for engine combustion is of much interest due to the fact that in practical engine simulations extensive computational time is spent solving the fuel oxidation and emission formation chemistry. A dynamic adaptive chemistry (DAC) scheme based on a directed relation graph error propagation (DRGEP) method has been applied to study homogeneous charge compression ignition (HCCI) engine combustion with detailed chemistry (over 500 species) previously using an R-value-based breadth-first search (RBFS) algorithm, which significantly reduced computational times (by as much as 30-fold). The present paper extends the use of this on-the-fly kinetic mechanism reduction scheme to model combustion in direct-injection (DI) engines. It was found that the DAC scheme becomes less efficient when applied to DI engine simulations using a kinetic mechanism of relatively small size and the accuracy of the original DAC scheme decreases for conventional non-premixed combustion engine. The present study also focuses on determination of search-initiating species, involvement of the NOx chemistry, selection of a proper error tolerance, as well as treatment of the interaction of chemical heat release and the fuel spray. Both the DAC schemes were integrated into the ERC KIVA-3v2 code, and simulations were conducted to compare the two schemes. In general, the present DAC scheme has better efficiency and similar accuracy compared to the previous DAC scheme. The efficiency depends on the size of the chemical kinetics mechanism used and the engine operating conditions. For cases using a small n-heptane kinetic mechanism of 34 species, 30% of the computational time is saved, and 50% for a larger n-heptane kinetic mechanism of 61 species. The paper also demonstrates that by combining the present DAC scheme with an adaptive multi-grid chemistry (AMC) solver, it is feasible to simulate a direct-injection engine using a detailed n-heptane mechanism with 543 species with practical computer time.

The single-zone numerical model of homogeneous charge compression ignition engine performance

NASA Astrophysics Data System (ADS)

Fedyanov, E. A.; Itkis, E. M.; Kuzmin, V. N.; Shumskiy, S. N.

2017-02-01

The single-zone model of methane-air mixture combustion in the Homogeneous Charge Compression Ignition engine was developed. First modeling efforts resulted in the selection of the detailed kinetic reaction mechanism, most appropriate for the conditions of the HCCI process. Then, the model was completed so as to simulate the performance of the four-stroke engine and was coupled by physically reasonable adjusting functions. Validation of calculations against experimental data showed acceptable agreement.

Ice Accretion Measurements on an Airfoil and Wedge in Mixed-Phase Conditions

NASA Technical Reports Server (NTRS)

Struk, Peter; Bartkus, Tadas; Tsao, Jen-Ching; Currie, Tom; Fuleki, Dan

2015-01-01

This paper describes ice accretion measurements from experiments conducted at the National Research Council (NRC) of Canada's Research Altitude Test Facility during 2012. Due to numerous engine power loss events associated with high altitude convective weather, potential ice accretion within an engine due to ice crystal ingestion is being investigated collaboratively by NASA and NRC. These investigations examine the physical mechanisms of ice accretion on surfaces exposed to ice crystal and mixed phase conditions, similar to those believed to exist in core compressor regions of jet engines. A further objective of these tests is to examine scaling effects since altitude appears to play a key role in this icing process.

High-Frequency Testing of Composite Fan Vanes With Erosion-Resistant Coating Conducted

NASA Technical Reports Server (NTRS)

Bowman, Cheryl L.; Sutter, James K.; Naik, Subhash; Otten, Kim D.; Perusek, Gail P.

2003-01-01

The mechanical integrity of hard, erosion-resistant coatings were tested using the Structural Dynamics Laboratory at the NASA Glenn Research Center. Under the guidance of Structural Mechanics and Dynamics Branch personnel, fixturing and test procedures were developed at Glenn to simulate engine vibratory conditions on coated polymer-matrix- composite bypass vanes using a slip table in the Structural Dynamics Laboratory. Results from the high-frequency mechanical bench testing, along with concurrent erosion testing of coupons and vanes, provided sufficient confidence to engine-endurance test similarly coated vane segments. The knowledge gained from this program will be applied to the development of oxidation- and erosion-resistant coatings for polymer matrix composite blades and vanes in future advanced turbine engines. Fan bypass vanes from the AE3007 (Rolls Royce America, Indianapolis, IN) gas turbine engine were coated by Engelhard (Windsor, CT) with compliant bond coatings and hard ceramic coatings. The coatings were developed collaboratively by Glenn and Allison Advanced Development Corporation (AADC)/Rolls Royce America through research sponsored by the High-Temperature Engine Materials Technology Project (HITEMP) and the Higher Operating Temperature Propulsion Components (HOTPC) project. High-cycle fatigue was performed through high-frequency vibratory testing on a shaker table. Vane resonant frequency modes were surveyed from 50 to 3000 Hz at input loads from 1g to 55g on both uncoated production vanes and vanes with the erosion-resistant coating. Vanes were instrumented with both lightweight accelerometers and strain gauges to establish resonance, mode shape, and strain amplitudes. Two high-frequency dwell conditions were chosen to excite two strain levels: one approaching the vane's maximum allowable design strain and another near the expected maximum strain during engine operation. Six specimens were tested per dwell condition. Pretest and posttest inspections were performed optically at up to 60 magnification and using a fluorescent-dye penetrant. Accumulation of 10 million cycles at a strain amplitude of two to three times that expected in the engine (approximately 670 Hz and 20g) led to the development of multiple cracks in the coating that were only detectable using fluorescent-dye penetrant inspection. Cracks were prevalent on the trailing edge and on the convex side of the midsection. No cracking or spalling was evident using standard optical inspection at up to 60 magnification. Further inspection may reveal whether these fine cracks penetrated the coating or were strictly on the surface. The dwell condition that simulated actual engine conditions produced no obvious surface flaws even after up to 80 million cycles had been accumulated at strain amplitudes produced at approximately 1500 Hz and 45g.

Application of mixing-controlled combustion models to gas turbine combustors

NASA Technical Reports Server (NTRS)

Nguyen, Hung Lee

1990-01-01

Gas emissions were studied from a staged Rich Burn/Quick-Quench Mix/Lean Burn combustor were studied under test conditions encountered in High Speed Research engines. The combustor was modeled at conditions corresponding to different engine power settings, and the effect of primary dilution airflow split on emissions, flow field, flame size and shape, and combustion intensity, as well as mixing, was investigated. A mathematical model was developed from a two-equation model of turbulence, a quasi-global kinetics mechanism for the oxidation of propane, and the Zeldovich mechanism for nitric oxide formation. A mixing-controlled combustion model was used to account for turbulent mixing effects on the chemical reaction rate. This model assumes that the chemical reaction rate is much faster than the turbulent mixing rate.

Emulation study on system characteristic of high pressure common-rail fuel injection system for marine medium-speed diesel engine

NASA Astrophysics Data System (ADS)

Wang, Qinpeng; Yang, Jianguo; Xin, Dong; He, Yuhai; Yu, Yonghua

2018-05-01

In this paper, based on the characteristic analyzing of the mechanical fuel injection system for the marine medium-speed diesel engine, a sectional high-pressure common rail fuel injection system is designed, rated condition rail pressure of which is 160MPa. The system simulation model is built and the performance of the high pressure common rail fuel injection system is analyzed, research results provide the technical foundation for the system engineering development.

Engine starting and stopping

NASA Astrophysics Data System (ADS)

Curnock, Barry

Different starter systems for jet engines are discussed: electric, cartridge, iso-propyl-nitrate, air, gas turbine, and hydraulic. The fuel system, ignition system, air flow control system, and actual starting mechanism of an air starter motor system are considered. The variation of engine parameters throughout a typical starting sequence are described, with reference to examples for an RB211-535 engine. Physical constraints on engine starting are considered: rotating stall, light up, the window between hang and stall, hang, compressor stall, and the effects of ambient conditions. The following are also discussed: contractual and airworthiness requirements; windmilling; inflight relighting; afterburning light up; combustion stability; and broken shafts. Graphics illustrating the above are presented.

Vibro-acoustic condition monitoring of Internal Combustion Engines: A critical review of existing techniques

NASA Astrophysics Data System (ADS)

Delvecchio, S.; Bonfiglio, P.; Pompoli, F.

2018-01-01

This paper deals with the state-of-the-art strategies and techniques based on vibro-acoustic signals that can monitor and diagnose malfunctions in Internal Combustion Engines (ICEs) under both test bench and vehicle operating conditions. Over recent years, several authors have summarized what is known in critical reviews mainly focused on reciprocating machines in general or on specific signal processing techniques: no attempts to deal with IC engine condition monitoring have been made. This paper first gives a brief summary of the generation of sound and vibration in ICEs in order to place further discussion on fault vibro-acoustic diagnosis in context. An overview of the monitoring and diagnostic techniques described in literature using both vibration and acoustic signals is also provided. Different faulty conditions are described which affect combustion, mechanics and the aerodynamics of ICEs. The importance of measuring acoustic signals, as opposed to vibration signals, is due since the former seem to be more suitable for implementation on on-board monitoring systems in view of their non-intrusive behaviour, capability in simultaneously capturing signatures from several mechanical components and because of the possibility of detecting faults affecting airborne transmission paths. In view of the recent needs of the industry to (-) optimize component structural durability adopting long-life cycles, (-) verify the engine final status at the end of the assembly line and (-) reduce the maintenance costs monitoring the ICE life during vehicle operations, monitoring and diagnosing system requests are continuously growing up. The present review can be considered a useful guideline for test engineers in understanding which types of fault can be diagnosed by using vibro-acoustic signals in sufficient time in both test bench and operating conditions and which transducer and signal processing technique (of which the essential background theory is here reported) could be considered the most reliable and informative to be implemented for the fault in question.

Implementation of partnership management model of SMK (Vocational High School) with existing industries in mechanical engineering expertise in Central Java

NASA Astrophysics Data System (ADS)

Sumbodo, Wirawan; Pardjono, Samsudi, Rahadjo, Winarno Dwi

2018-03-01

This study aims to determine the existing conditions of implementation of partnership management model of SMK with the industry on the mechanical engineering expertise in Central Java. The method used is descriptive analysis. The research result shows that the implementation of partnership management model of SMK based on new existing industry produces ready graduates of 62.5% which belongs to low category, although the partnership program of SMK with the industry is done well with the average score of 3.17. As many as 37.5% of SMK graduates of Mechanical Engineering Expertise Program choose to continue their studies or to be an entrepreneur. It is expected that the partnership model of SMK with the industry can be developed into a reference for government policy in developing SMK that is able to produce graduates who are ready to work according to the needs of partner industry.

Analysis of a topping-cycle, aircraft, gas-turbine-engine system which uses cryogenic fuel

NASA Technical Reports Server (NTRS)

Turney, G. E.; Fishbach, L. H.

1984-01-01

A topping-cycle aircraft engine system which uses a cryogenic fuel was investigated. This system consists of a main turboshaft engine that is mechanically coupled (by cross-shafting) to a topping loop, which augments the shaft power output of the system. The thermodynamic performance of the topping-cycle engine was analyzed and compared with that of a reference (conventional) turboshaft engine. For the cycle operating conditions selected, the performance of the topping-cycle engine in terms of brake specific fuel consumption (bsfc) was determined to be about 12 percent better than that of the reference turboshaft engine. Engine weights were estimated for both the topping-cycle engine and the reference turboshaft engine. These estimates were based on a common shaft power output for each engine. Results indicate that the weight of the topping-cycle engine is comparable with that of the reference turboshaft engine.

Study of LH2-fueled topping cycle engine for aircraft propulsion

NASA Technical Reports Server (NTRS)

Turney, G. E.; Fishbach, L. H.

1983-01-01

An analytical investigation was made of a topping cycle aircraft engine system which uses a cryogenic fuel. This system consists of a main turboshaft engine which is mechanically coupled (by cross-shafting) to a topping loop which augments the shaft power output of the system. The thermodynamic performance of the topping cycle engine was analyzed and compared with that of a reference (conventional-type) turboshaft engine. For the cycle operating conditions selected, the performance of the topping cycle engine in terms of brake specific fuel consumption (bsfc) was determined to be about 12 percent better than that of the reference turboshaft engine. Engine weights were estimated for both the topping cycle engine and the reference turboshaft engine. These estimates were based on a common shaft power output for each engine. Results indicate that the weight of the topping cycle engine is comparable to that of the reference turboshaft engine.

Pulsejet engine dynamics in vertical motion using momentum conservation

NASA Astrophysics Data System (ADS)

Cheche, Tiberius O.

2017-03-01

The momentum conservation law is applied to analyse the dynamics of a pulsejet engine in vertical motion in a uniform gravitational field in the absence of friction. The model predicts the existence of a terminal speed given the frequency of the short pulses. The conditions where the engine does not return to the starting position are identified. The number of short periodic pulses after which the engine returns to the starting position is found to be independent of the exhaust velocity and gravitational field intensity for a certain frequency of pulses. The pulsejet engine and turbojet engine aircraft models of dynamics are compared. Also the octopus dynamics is modelled. The paper is addressed to intermediate undergraduate students of classical mechanics and aerospace engineering.

International Symposium on Numerical Methods in Engineering, 5th, Ecole Polytechnique Federale de Lausanne, Switzerland, Sept. 11-15, 1989, Proceedings. Volumes 1 & 2

NASA Astrophysics Data System (ADS)

Gruber, Ralph; Periaux, Jaques; Shaw, Richard Paul

Recent advances in computational mechanics are discussed in reviews and reports. Topics addressed include spectral superpositions on finite elements for shear banding problems, strain-based finite plasticity, numerical simulation of hypersonic viscous continuum flow, constitutive laws in solid mechanics, dynamics problems, fracture mechanics and damage tolerance, composite plates and shells, contact and friction, metal forming and solidification, coupling problems, and adaptive FEMs. Consideration is given to chemical flows, convection problems, free boundaries and artificial boundary conditions, domain-decomposition and multigrid methods, combustion and thermal analysis, wave propagation, mixed and hybrid FEMs, integral-equation methods, optimization, software engineering, and vector and parallel computing.

Aerosols emitted in underground mine air by diesel engine fueled with biodiesel.

PubMed

Bugarski, Aleksandar D; Cauda, Emanuele G; Janisko, Samuel J; Hummer, Jon A; Patts, Larry D

2010-02-01

Using biodiesel in place of petroleum diesel is considered by several underground metal and nonmetal mine operators to be a viable strategy for reducing the exposure of miners to diesel particulate matter. This study was conducted in an underground experimental mine to evaluate the effects of soy methyl ester biodiesel on the concentrations and size distributions of diesel aerosols and nitric oxides in mine air. The objective was to compare the effects of neat and blended biodiesel fuels with those of ultralow sulfur petroleum diesel. The evaluation was performed using a mechanically controlled, naturally aspirated diesel engine equipped with a muffler and a diesel oxidation catalyst. The effects of biodiesel fuels on size distributions and number and total aerosol mass concentrations were found to be strongly dependent on engine operating conditions. When fueled with biodiesel fuels, the engine contributed less to elemental carbon concentrations for all engine operating modes and exhaust configurations. The substantial increases in number concentrations and fraction of organic carbon (OC) in total carbon over the baseline were observed when the engine was fueled with biodiesel fuels and operated at light-load operating conditions. Size distributions for all test conditions were found to be single modal and strongly affected by engine operating conditions, fuel type, and exhaust configuration. The peak and total number concentrations as well as median diameter decreased with an increase in the fraction of biodiesel in the fuels, particularly for high-load operating conditions. The effects of the diesel oxidation catalyst, commonly deployed to counteract the potential increase in OC emissions due to use of biodiesel, were found to vary depending upon fuel formulation and engine operating conditions. The catalyst was relatively effective in reducing aerosol number and mass concentrations, particularly at light-load conditions, but also showed the potential for an increase in nitrogen dioxide concentrations at high-load modes.

Mechanical Properties Experimental Study of Engineering Vehicle Refurbished Tire

NASA Astrophysics Data System (ADS)

Qiang, Wang; Xiaojie, Qi; Zhao, Yang; Yunlong, Wang; Guotian, Wang; Degang, Lv

2018-05-01

The vehicle refurbished tire test system was constructed, got load-deformation, load-stiffness, and load-compression ratio property laws of engineering vehicle refurbished tire under the working condition of static state and ground contact, and built radial direction loading deformation mathematics model of 26.5R25 engineering vehicle refurbished tire. The test results show that radial-direction and side-direction deformation value is a little less than that of the new tire. The radial-direction stiffness and compression ratio of engineering vehicle refurbished tire were greatly influenced by radial-direction load and air inflation pressure. When load was certain, radial-direction stiffness would increase with air inflation pressure increasing. When air inflation pressure was certain, compression ratio of engineering vehicle refurbished tire would enlarge with radial-direction load increasing, which was a little less than that of the new and the same type tire. Aging degree of old car-case would exert a great influence on deformation property of engineering vehicle refurbished tire, thus engineering vehicle refurbished tires are suitable to the working condition of low tire pressure and less load.

Thick thermal barrier coatings for diesel engines

NASA Technical Reports Server (NTRS)

Beardsley, M. Brad

1995-01-01

Caterpillar's approach to applying thick thermal barrier coatings (TTBC's) to diesel engine combustion chambers has been to use advanced modeling techniques to predict engine conditions and combine this information with fundamental property evaluation of TTBC systems to predict engine performance and TTBC stress states. Engine testing has been used to verify the predicted performance of the TTBC systems and provide information on failure mechanisms. The objective Caterpillar's program to date has been to advance the fundamental understanding of thick thermal barrier coating systems. Previous reviews of thermal barrier coating technology concluded that the current level of understanding of coating system behavior is inadequate and the lack of fundamental understanding may impeded the application of TTBC's to diesel engines. Areas of TTBC technology being examined in this program include powder characteristics and chemistry; bond coat composition; coating design, microstructure, and thickness as they affect properties, durability, and reliability; and TTBC 'aging' effects (microstructural and property changes) under diesel engine operating conditions. Methods to evaluate the reliability and durability of TTBC's have been developed that attempt to understand the fundamental strength of TTBC's for particular stress states.

Thick thermal barrier coatings for diesel engines

NASA Technical Reports Server (NTRS)

Beardsley, M. B.

1995-01-01

Caterpillar's approach to applying Thick Thermal Barrier Coatings (TTBC's) to diesel engine combustion chambers has been to use advanced modeling techniques to predict engine conditions and combine this information with fundamental property evaluation of TTBC systems to predict engine performance and TTBC stress states. Engine testing has been used to verify the predicted performance of the TTBC systems and provide information on failure mechanisms. The objective of Caterpillar's subcontract with ORNL is to advance the fundamental understanding of thick thermal barrier coating systems. Previous reviews of thermal barrier coating technology concluded that the current level of understanding of coating system behavior is inadequate and the lack of fundamental understanding may impede the application of TTBC's to diesel engines. Areas of TTBC technology being examined in this program include powder characteristics and chemistry; bond coat composition; coating design, microstructure, and thickness as they affect properties, durability, and reliability; and TTBC 'aging' effects (microstructural and property changes) under diesel engine operating conditions. Methods to evaluate the reliability and durability of TTBC's have been developed that attempt to understand the fundamental strength of TTBC's for particular stress states.

Alternating air-medium exposure in rotating bioreactors optimizes cell metabolism in 3D novel tubular scaffold polyurethane foams.

PubMed

Tresoldi, Claudia; Stefani, Ilaria; Ferracci, Gaia; Bertoldi, Serena; Pellegata, Alessandro F; Farè, Silvia; Mantero, Sara

2017-04-26

In vitro dynamic culture conditions play a pivotal role in developing engineered tissue grafts, where the supply of oxygen and nutrients, and waste removal must be permitted within construct thickness. For tubular scaffolds, mass transfer is enhanced by introducing a convective flow through rotating bioreactors with positive effects on cell proliferation, scaffold colonization and extracellular matrix deposition. We characterized a novel polyurethane-based tubular scaffold and investigated the impact of 3 different culture configurations over cell behavior: dynamic (i) single-phase (medium) rotation and (ii) double-phase exposure (medium-air) rotation; static (iii) single-phase static culture as control. A new mixture of polyol was tested to create polyurethane foams (PUFs) as 3D scaffold for tissue engineering. The structure obtained was morphologically and mechanically analyzed tested. Murine fibroblasts were externally seeded on the novel porous PUF scaffold, and cultured under different dynamic conditions. Viability assay, DNA quantification, SEM and histological analyses were performed at different time points. The PUF scaffold presented interesting mechanical properties and morphology adequate to promote cell adhesion, highlighting its potential for tissue engineering purposes. Results showed that constructs under dynamic conditions contain enhanced viability and cell number, exponentially increased for double-phase rotation; under this last configuration, cells uniformly covered both the external surface and the lumen. The developed 3D structure combined with the alternated exposure to air and medium provided the optimal in vitro biochemical conditioning with adequate nutrient supply for cells. The results highlight a valuable combination of material and dynamic culture for tissue engineering applications.

Oxygen tension differentially regulates the functional properties of cartilaginous tissues engineered from infrapatellar fat pad derived MSCs and articular chondrocytes.

PubMed

Buckley, C T; Vinardell, T; Kelly, D J

2010-10-01

For current tissue engineering or regenerative medicine strategies, chondrocyte (CC)- or mesenchymal stem cell (MSC)-seeded constructs are typically cultured in normoxic conditions (20% oxygen). However, within the knee joint capsule a lower oxygen tension exists. The objective of this study was to investigate how CCs and infrapatellar fad pad derived MSCs will respond to a low oxygen (5%) environment in 3D agarose culture. Our hypothesis was that culture in a low oxygen environment (5%) will enhance the functional properties of cartilaginous tissues engineered using both cell sources. Cell-encapsulated agarose hydrogel constructs (seeded with CCs or infrapatellar fat pad (IFP) derived MSCs) were prepared and cultured in a chemically defined serum-free medium in the presence (CCs and MSCs) or absence (CCs only) of transforming growth factor-beta3 (TGF-β3) in normoxic (20%) or low oxygen (5%) conditions for 42 days. Constructs were assessed at days 0, 21 and 42 in terms of mechanical properties, biochemical content and histologically. Low oxygen tension (5%) was observed to promote extracellular matrix (ECM) production by CCs cultured in the absence of TGF-β3, but was inhibitory in the presence of TGF-β3. In contrast, a low oxygen tension enhanced chondrogenesis of IFP constructs in the presence of TGF-β3, leading to superior mechanical functionality compared to CCs cultured in identical conditions. Extrapolating the results of this study to the in vivo setting, it would appear that joint fat pad derived MSCs may possess a superior potential to generate a functional repair tissue in low oxygen tensions. However, in the context of in vitro cartilage tissue engineering, CCs maintained in normoxic conditions in the presence of TGF-β3 generate the most mechanically functional tissue. Copyright © 2010 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

Research on corrosion mechanism of suspension insulator steel foot of direct current system and measures for corrosion inhibition

NASA Astrophysics Data System (ADS)

Chen, He; Yang, Yueguang; Su, Guolei; Wang, Xiaoqing; Zhang, Hourong; Sun, Xiaoyu; Fan, Youping

2017-09-01

There are increasingly serious electrocorrosion phenomena on insulator hardware caused by direct current transmission due to the wide-range popularization of extra high voltage direct current transmission engineering in our country. Steel foot corrosion is the main corrosion for insulators on positive polarity side of transmission lines. On one hand, the corrosion leads to the tapering off of steel foot diameter, having a direct influence on mechanical property of insulators; on the other hand, in condition of corrosion on steel foot wrapped in porcelain ware, the volume of the corrosion product is at least 50% more than that of the original steel foot, leading to bursting of porcelain ware, threatening safe operation of transmission lines. Therefore, it is necessary to conduct research on the phenomenon and propose feasible measures for corrosion inhibition. Starting with the corrosion mechanism, this article proposes two measures for corrosion inhibition, and verifies the inhibition effect in laboratory conditions, providing reference for application in engineering.

High Throughput and Mechano-Active Platforms to Promote Cartilage Regeneration and Repair

NASA Astrophysics Data System (ADS)

Mohanraj, Bhavana

Traumatic joint injuries initiate acute degenerative changes in articular cartilage that can lead to progressive loss of load-bearing function. As a result, patients often develop post-traumatic osteoarthritis (PTOA), a condition for which there currently exists no biologic interventions. To address this need, tissue engineering aims to mimic the structure and function of healthy, native counterparts. These constructs can be used to not only replace degenerated tissue, but also build in vitro, pre-clinical models of disease. Towards this latter goal, this thesis focuses on the design of a high throughput system to screen new therapeutics in a micro-engineered model of PTOA, and the development of a mechanically-responsive drug delivery system to augment tissue-engineered approaches for cartilage repair. High throughput screening is a powerful tool for drug discovery that can be adapted to include 3D tissue constructs. To facilitate this process for cartilage repair, we built a high throughput mechanical injury platform to create an engineered cartilage model of PTOA. Compressive injury of functionally mature constructs increased cell death and proteoglycan loss, two hallmarks of injury observed in vivo. Comparison of this response to that of native cartilage explants, and evaluation of putative therapeutics, validated this model for subsequent use in small molecule screens. A primary screen of 118 compounds identified a number of 'hits' and relevant pathways that may modulate pathologic signaling post-injury. To complement this process of therapeutic discovery, a stimuli-responsive delivery system was designed that used mechanical inputs as the 'trigger' mechanism for controlled release. The failure thresholds of these mechanically-activated microcapsules (MAMCs) were influenced by physical properties and composition, as well as matrix mechanical properties in 3D environments. TGF-beta released from the system upon mechano-activation stimulated stem cell chondrogenesis, demonstrating the potential of MAMCs to actively deliver therapeutics within demanding mechanical environments. Taken together, this work advances our capacity to identify and deliver new compounds of clinical relevance to modulate disease progression following traumatic injury using state-of-the-art micro-engineered screening tools and a novel mechanically-activated delivery system. These platforms advance strategies for cartilage repair and regeneration in PTOA and provide new options for the treatment of this debilitating condition.

Nonlinear heat transfer and structural analyses of SSME turbine blades

NASA Technical Reports Server (NTRS)

Abdul-Aziz, A.; Kaufman, A.

1987-01-01

Three-dimensional nonlinear finite-element heat transfer and structural analyses were performed for the first stage high-pressure fuel turbopump blade of the space shuttle main engine (SSME). Directionally solidified (DS) MAR-M 246 material properties were considered for the analyses. Analytical conditions were based on a typical test stand engine cycle. Blade temperature and stress-strain histories were calculated using MARC finite-element computer code. The study was undertaken to assess the structural response of an SSME turbine blade and to gain greater understanding of blade damage mechanisms, convective cooling effects, and the thermal-mechanical effects.

Right tail increasing dependence between scores

NASA Astrophysics Data System (ADS)

Fernández, M.; García, Jesús E.; González-López, V. A.; Romano, N.

2017-07-01

In this paper we investigate the behavior of the conditional probability Prob(U > u|V > v) of two records coming from students of an undergraduate course, where U is the score of calculus I, scaled in [0, 1] and V is the score of physics scaled in [0, 1], the physics subject is part of the admission test of the university. For purposes of comparison, we consider two different undergraduate courses, electrical engineering and mechanical engineering, during nine years, from 2003 to 2011. Through a Bayesian perspective we estimate Prob(U > u|V > v) year by year and course by course. We conclude that U is right tail increasing in V, in both courses and for all the years. Moreover, over these nine years, we observe different ranges of variability for the estimated probabilities of electrical engineering when compared to the estimated probabilities of mechanical engineering.

Effect of load on the tribological properties of hypereutectic Al-Si alloy under boundary lubrication conditions

NASA Astrophysics Data System (ADS)

Kumar, Parveen; Wani, M. F.

2017-11-01

Researchers reported that the IC engine components (piston, cylinder liner etc) fail due to the friction losses (~45%) and wear losses (~25-40%). So the demand of light weight, low friction and wear resistance alloys increases day by day, which reduces the emission and increases the efficiency of the IC engine. In this connection, tribological tests on hypereutectic Al-25Si alloy were performed using a ball-on-disk configuration under dry and lubricated sliding conditions. Hypereutectic Al-25Si alloy was prepared by rapid solidification process with T6 condition. T6 condition improves the friction, wear and mechanical properties of the alloy. Friction coefficient and wear rate of the alloy was measured under high loads ranging from 100 to 300 N. It was found that the friction coefficient (COF) and wear rate of hypereutectic Al-25Si alloy/steel tribo pair increased with increase in load. Significant reduction in COF and wear rate was accomplished with SAE20W50 engine oil and Si particles act as solid lubricant. Optical microscope, 3D surface profilometer and scanning electron microscope (SEM) coupled with an energy dispersive spectrometer (EDS) were used for characterization the worn surface morphologies. The morphology, size and distribution of high Si particles due to its fabrication process caused the improvements in COF and wear rate under lubricated conditions. Adhesive wear, abrasive wear and plastic deformation acted as the dominant wear mechanism for hypereutectic Al-25Si alloy.

Experimental and analytical study of ceramic-coated turbine-tip shroud seals for small turbine engines

NASA Technical Reports Server (NTRS)

Biesiadny, T. J.; Mcdonald, G. E.; Hendricks, R. C.; Little, J. K.; Robinson, R. A.; Klann, G. A.; Lassow, E. S.

1985-01-01

The results of an experimental and analytical evaluation of ceramic turbine tip shrouds within a small turbine engine operating environment are presented. The ceramic shrouds were subjected to 1001 cycles between idle and high power and steady-state conditions for a total of 57.8 engine hr. Posttest engine inspection revealed mud-flat surface cracking, which was attributed to microcracking under tension with crack penetration to the ceramic and bond coat interface. Sections and micrographs tend to corroborate the thesis. The engine test data provided input to a thermomechanical analysis to predict temperature and stress profiles throughout the ceramic gas-path seal. The analysis predicts cyclic thermal stresses large enough to cause the seal to fail. These stresses are, however, mitigated by inelastic behavior of the shroud materials and by the microfracturing that tensile stresses produce. Microfracturing enhances shroud longevity during early life but provides the failure mechanism during life but provides the failure mechanism during extended life when coupled with the time dependent inelastic materials effects.

An experimental and modeling study investigating the ignition delay in a military diesel engine running hexadecane (cetane) fuel

DOE PAGES

Cowart, Jim S.; Fischer, Warren P.; Hamilton, Leonard J.; ...

2013-02-01

In an effort aimed at predicting the combustion behavior of a new fuel in a conventional diesel engine, cetane (n-hexadecane) fuel was used in a military engine across the entire speed–load operating range. The ignition delay was characterized for this fuel at each operating condition. A chemical ignition delay was also predicted across the speed–load range using a detailed chemical kinetic mechanism with a constant pressure reactor model. At each operating condition, the measured in-cylinder pressure and predicted temperature at the start of injection were applied to the detailed n-hexadecane kinetic mechanism, and the chemical ignition delay was predicted withoutmore » any kinetic mechanism calibration. The modeling results show that fuel–air parcels developed from the diesel spray with an equivalence ratio of 4 are the first to ignite. The chemical ignition delay results also showed decreasing igntion delays with increasing engine load and speed, just as the experimental data revealed. At lower engine speeds and loads, the kinetic modeling results show the characteristic two-stage negative temperature coefficient behavior of hydrocarbon fuels. However, at high engine speeds and loads, the reactions do not display negative temperature coefficient behavior, as the reactions proceed directly into high-temperature pathways due to higher temperatures and pressure at injection. A moderate difference between the total and chemical ignition delays was then characterized as a phyical delay period that scales inversely with engine speed. This physical delay time is representative of the diesel spray development time and is seen to become a minority fraction of the total igntion delay at higher engine speeds. In addition, the approach used in this study suggests that the ignition delay and thus start of combustion may be predicted with reasonable accuracy using kinetic modeling to determine the chemical igntion delay. Then, in conjunction with the physical delay time (experimental or modeling based), a new fuel’s acceptability in a conventional engine could be assessed by determining that the total ignition delay is not too short or too long.« less

Mechanical Stimulation Protocols of Human Derived Cells in Articular Cartilage Tissue Engineering - A Systematic Review.

PubMed

Khozoee, Baktash; Mafi, Pouya; Mafi, Reza; Khan, Wasim S

2017-01-01

Mechanical stimulation is a key factor in articular cartilage generation and maintenance. Bioreactor systems have been designed and built in order to deliver specific types of mechanical stimulation. The focus has been twofold, applying a type of preconditioning in order to stimulate cell differentiation, and to simulate in vivo conditions in order to gain further insight into how cells respond to different stimulatory patterns. Due to the complex forces at work within joints, it is difficult to simulate mechanical conditions using a bioreactor. The aim of this review is to gain a deeper understanding of the complexities of mechanical stimulation protocols by comparing those employed in bioreactors in the context of tissue engineering for articular cartilage, and to consider their effects on cultured cells. Allied and Complementary Medicine 1985 to 2016, Ovid MEDLINE[R] 1946 to 2016, and Embase 1974 to 2016 were searched using key terms. Results were subject to inclusion and exclusion criteria, key findings summarised into a table and subsequently discussed. Based on this review it is overwhelmingly clear that mechanical stimulation leads to increased chondrogenic properties in the context of bioreactor articular cartilage tissue engineering using human cells. However, given the variability and lack of controlled factors between research articles, results are difficult to compare, and a standardised method of evaluating stimulation protocols proved challenging. With improved standardisation in mechanical stimulation protocol reporting, bioreactor design and building processes, along with a better understanding of joint behaviours, we hope to perform a meta-analysis on stimulation protocols and methods. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Thick-film acoustic emission sensors for use in structurally integrated condition-monitoring applications.

PubMed

Pickwell, Andrew J; Dorey, Robert A; Mba, David

2011-09-01

Monitoring the condition of complex engineering structures is an important aspect of modern engineering, eliminating unnecessary work and enabling planned maintenance, preventing failure. Acoustic emissions (AE) testing is one method of implementing continuous nondestructive structural health monitoring. A novel thick-film (17.6 μm) AE sensor is presented. Lead zirconate titanate thick films were fabricated using a powder/sol composite ink deposition technique and mechanically patterned to form a discrete thick-film piezoelectric AE sensor. The thick-film sensor was benchmarked against a commercial AE device and was found to exhibit comparable responses to simulated acoustic emissions.

Thermomechanical Multiaxial Fatigue Testing Capability Developed

NASA Technical Reports Server (NTRS)

1996-01-01

Structural components in aeronautical gas turbine engines typically experience multiaxial states of stress under nonisothermal conditions. To estimate the durability of the various components in the engine, one must characterize the cyclic deformation and fatigue behavior of the materials used under thermal and complex mechanical loading conditions. To this end, a testing protocol and associated test control software were developed at the NASA Lewis Research Center for thermomechanical axial-torsional fatigue tests. These tests are to be performed on thin-walled, tubular specimens fabricated from the cobalt-based superalloy Haynes 188. The software is written in C and runs on an MS-DOS based microcomputer.

Co-culture systems-based strategies for articular cartilage tissue engineering.

PubMed

Zhang, Yu; Guo, Weimin; Wang, Mingjie; Hao, Chunxiang; Lu, Liang; Gao, Shuang; Zhang, Xueliang; Li, Xu; Chen, Mingxue; Li, Penghao; Jiang, Peng; Lu, Shibi; Liu, Shuyun; Guo, Quanyi

2018-03-01

Cartilage engineering facilitates repair and regeneration of damaged cartilage using engineered tissue that restores the functional properties of the impaired joint. The seed cells used most frequently in tissue engineering, are chondrocytes and mesenchymal stem cells. Seed cells activity plays a key role in the regeneration of functional cartilage tissue. However, seed cells undergo undesirable changes after in vitro processing procedures, such as degeneration of cartilage cells and induced hypertrophy of mesenchymal stem cells, which hinder cartilage tissue engineering. Compared to monoculture, which does not mimic the in vivo cellular environment, co-culture technology provides a more realistic microenvironment in terms of various physical, chemical, and biological factors. Co-culture technology is used in cartilage tissue engineering to overcome obstacles related to the degeneration of seed cells, and shows promise for cartilage regeneration and repair. In this review, we focus first on existing co-culture systems for cartilage tissue engineering and related fields, and discuss the conditions and mechanisms thereof. This is followed by methods for optimizing seed cell co-culture conditions to generate functional neo-cartilage tissue, which will lead to a new era in cartilage tissue engineering. © 2017 Wiley Periodicals, Inc.

Influence of thermodynamic mechanism of inter- facial adsorption on purifying air-conditioning engineering under intensification of electric field

NASA Astrophysics Data System (ADS)

Chen, Yun-Yu

2016-12-01

As a kind of mass transfer process as well as the basis of separating and purifying mixtures, interfacial adsorption has been widely applied to fields like chemical industry, medical industry and purification engineering in recent years. Influencing factors of interfacial adsorption, in addition to the traditional temperature, intensity of pressure, amount of substance and concentration, also include external fields, such as magnetic field, electric field and electromagnetic field, etc. Starting from the point of thermodynamics and taking the Gibbs adsorption as the model, the combination of energy axiom and the first law of thermodynamics was applied to boundary phase, and thus the theoretical expression for the volume of interface absorption under electric field as well as the mathematical relationship between surface tension and electric field intensity was obtained. In addition, according to the obtained theoretical expression, the volume of interface absorption of ethanol solution under different electric field intensities and concentrations was calculated. Moreover, the mechanism of interfacial adsorption was described from the perspective of thermodynamics and the influence of electric field on interfacial adsorption was explained reasonably, aiming to further discuss the influence of thermodynamic mechanism of interfacial adsorption on purifying air-conditioning engineering under intensification of electric field.

Performance retention of the RB211 powerplant in service

NASA Technical Reports Server (NTRS)

Astridge, B. L.; Pinder, J. T.

1981-01-01

An understanding of the mechanisms of deterioration is essential in order that features to counteract performance degradation can be built into the basic design of an engine and nacelle. Furthermore, the interpretation must be continued in service for effective feedback to provide modifications which may be necessary in maintaining a satisfactory performance retention program. The in service assessment must be accurate as to magnitude and causes and this requires consideration of: (1) the powerplant as a complete entity, i.e., the engine components and nacelle including the thrust reverser; (2) measurement of performance in flight rather than by sole reliance on the scaling of test cell data to flight conditions (although some correlation should be possible); and (3) the relationship of engine parts condition to overhaul performance and in flight deterioration level of that engine. These aspects are addressed by consideration of the RB211 engine in service in both the Lockheed L1011 Tristar and Boeing 747 aircraft.

A Multicomponent Blend as a Diesel Fuel Surrogate for Compression Ignition Engine Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pei, Yuanjiang; Mehl, Marco; Liu, Wei

A mixture of n-dodecane and m-xylene is investigated as a diesel fuel surrogate for compression ignition engine applications. Compared to neat n-dodecane, this binary mixture is more representative of diesel fuel because it contains an alkyl-benzene which represents an important chemical class present in diesel fuels. A detailed multi-component mechanism for n-dodecane and m-xylene was developed by combining a previously developed n-dodecane mechanism with a recently developed mechanism for xylenes. The xylene mechanism is shown to reproduce experimental ignition data from a rapid compression machine and shock tube, speciation data from the jet stirred reactor and flame speed data. Thismore » combined mechanism was validated by comparing predictions from the model with experimental data for ignition in shock tubes and for reactivity in a flow reactor. The combined mechanism, consisting of 2885 species and 11754 reactions, was reduced to a skeletal mechanism consisting 163 species and 887 reactions for 3D diesel engine simulations. The mechanism reduction was performed using directed relation graph (DRG) with expert knowledge (DRG-X) and DRG-aided sensitivity analysis (DRGASA) at a fixed fuel composition of 77% of n-dodecane and 23% m-xylene by volume. The sample space for the reduction covered pressure of 1 – 80 bar, equivalence ratio of 0.5 – 2.0, and initial temperature of 700 – 1600 K for ignition. The skeletal mechanism was compared with the detailed mechanism for ignition and flow reactor predictions. Finally, the skeletal mechanism was validated against a spray flame dataset under diesel engine conditions documented on the Engine Combustion Network (ECN) website. These multi-dimensional simulations were performed using a Representative Interactive Flame (RIF) turbulent combustion model. Encouraging results were obtained compared to the experiments with regards to the predictions of ignition delay and lift-off length at different ambient temperatures.« less

Cell Microenvironment Engineering and Monitoring for Tissue Engineering and Regenerative Medicine: The Recent Advances

PubMed Central

Barthes, Julien; Özçelik, Hayriye; Hindié, Mathilde; Ndreu-Halili, Albana; Hasan, Anwarul

2014-01-01

In tissue engineering and regenerative medicine, the conditions in the immediate vicinity of the cells have a direct effect on cells' behaviour and subsequently on clinical outcomes. Physical, chemical, and biological control of cell microenvironment are of crucial importance for the ability to direct and control cell behaviour in 3-dimensional tissue engineering scaffolds spatially and temporally. In this review, we will focus on the different aspects of cell microenvironment such as surface micro-, nanotopography, extracellular matrix composition and distribution, controlled release of soluble factors, and mechanical stress/strain conditions and how these aspects and their interactions can be used to achieve a higher degree of control over cellular activities. The effect of these parameters on the cellular behaviour within tissue engineering context is discussed and how these parameters are used to develop engineered tissues is elaborated. Also, recent techniques developed for the monitoring of the cell microenvironment in vitro and in vivo are reviewed, together with recent tissue engineering applications where the control of cell microenvironment has been exploited. Cell microenvironment engineering and monitoring are crucial parts of tissue engineering efforts and systems which utilize different components of the cell microenvironment simultaneously can provide more functional engineered tissues in the near future. PMID:25143954

Cell microenvironment engineering and monitoring for tissue engineering and regenerative medicine: the recent advances.

PubMed

Barthes, Julien; Özçelik, Hayriye; Hindié, Mathilde; Ndreu-Halili, Albana; Hasan, Anwarul; Vrana, Nihal Engin

2014-01-01

In tissue engineering and regenerative medicine, the conditions in the immediate vicinity of the cells have a direct effect on cells' behaviour and subsequently on clinical outcomes. Physical, chemical, and biological control of cell microenvironment are of crucial importance for the ability to direct and control cell behaviour in 3-dimensional tissue engineering scaffolds spatially and temporally. In this review, we will focus on the different aspects of cell microenvironment such as surface micro-, nanotopography, extracellular matrix composition and distribution, controlled release of soluble factors, and mechanical stress/strain conditions and how these aspects and their interactions can be used to achieve a higher degree of control over cellular activities. The effect of these parameters on the cellular behaviour within tissue engineering context is discussed and how these parameters are used to develop engineered tissues is elaborated. Also, recent techniques developed for the monitoring of the cell microenvironment in vitro and in vivo are reviewed, together with recent tissue engineering applications where the control of cell microenvironment has been exploited. Cell microenvironment engineering and monitoring are crucial parts of tissue engineering efforts and systems which utilize different components of the cell microenvironment simultaneously can provide more functional engineered tissues in the near future.

Strain engineered pyrochlore at high pressure

DOE PAGES

Rittman, Dylan R.; Turner, Katlyn M.; Park, Sulgiye; ...

2017-05-22

Strain engineering is a promising method for next-generation materials processing techniques. Here, we use mechanical milling and annealing followed by compression in diamond anvil cell to tailor the intrinsic and extrinsic strain in pyrochlore, Dy 2Ti 2O 7 and Dy 2Zr 2O 7. Raman spectroscopy, X-ray pair distribution function analysis, and X-ray diffraction were used to characterize atomic order over short-, medium-, and long-range spatial scales, respectively, under ambient conditions. Raman spectroscopy and X-ray diffraction were further employed to interrogate the material in situ at high pressure. High-pressure behavior is found to depend on the species and concentration of defectsmore » in the sample at ambient conditions. Overall, we show that defects can be engineered to lower the phase transformation onset pressure by ~50% in the ordered pyrochlore Dy 2Ti 2O 7, and lower the phase transformation completion pressure by ~20% in the disordered pyrochlore Dy 2Zr 2O 7. Lastly, these improvements are achieved without significantly sacrificing mechanical integrity, as characterized by bulk modulus.« less

Thermal-structural design study of an airframe-integrated Scramjet

NASA Technical Reports Server (NTRS)

Killackey, J. J.; Katinsky, E. A.; Tepper, S.; Vuigner, A. A.

1978-01-01

Design concepts are developed and evaluated for a cooled structures assembly for the Scramjet engine, for engine subsystems mass, volume, and operating requirements, and for the aircraft/engine interface. A thermal protection system was defined that makes it possible to attain a life of 100 hours and 1000 cycles. The coolant equivalence ratio at the Mach 10 maximum thermal loading condition is 0.6, indicating a capacity for airframe cooling. The mechanical design is feasible for manufacture using conventional materials. For the cooled structures in a six-module engine, the mass per unit capture area is 12.4 KN/sq m. The total weight of a six-module engine assembly including the fuel system is 14.73 KN.

On the Effects of Unsteady Flow Conditions on the Performance of a Cross Flow Hydrokinetic Turbine

DTIC Science & Technology

2017-05-22

of Marine Energy BEI Sensors Ocean Engineering Mechanics: With Applications US Department of Commerce, National Oceanic and Atmospheric Administration, National Weather Service, National Data Buoy Center.

Failure Engineering Study and Accelerated Stress Test Results for the Mars Global Surveyor Spacecraft's Power Shunt Assemblies

NASA Technical Reports Server (NTRS)

Gibbel, Mark; Larson, Timothy

2000-01-01

An Engineering-of-Failure approach to designing and executing an accelerated product qualification test was performed to support a risk assessment of a "work-around" necessitated by an on-orbit failure of another piece of hardware on the Mars Global Surveyor spacecraft. The proposed work-around involved exceeding the previous qualification experience both in terms of extreme cold exposure level and in terms of demonstrated low cycle fatigue life for the power shunt assemblies. An analysis was performed to identify potential failure sites, modes and associated failure mechanisms consistent with the new use conditions. A test was then designed and executed which accelerated the failure mechanisms identified by analysis. Verification of the resulting failure mechanism concluded the effort.

Quantitative ultrasonic evaluation of mechanical properties of engineering materials

NASA Technical Reports Server (NTRS)

Vary, A.

1978-01-01

Current progress in the application of ultrasonic techniques to nondestructive measurement of mechanical strength properties of engineering materials is reviewed. Even where conventional NDE techniques have shown that a part is free of overt defects, advanced NDE techniques should be available to confirm the material properties assumed in the part's design. There are many instances where metallic, composite, or ceramic parts may be free of critical defects while still being susceptible to failure under design loads due to inadequate or degraded mechanical strength. This must be considered in any failure prevention scheme that relies on fracture analysis. This review will discuss the availability of ultrasonic methods that can be applied to actual parts to assess their potential susceptibility to failure under design conditions.

Strain measurements in a rotary engine housing

NASA Technical Reports Server (NTRS)

Lee, C. M.; Bond, T. H.; Addy, H. E.; Chun, K. S.; Lu, C. Y.

1989-01-01

The development of structural design tools for Rotary Combustion Engines (RCE) using Finite Element Modeling (FEM) requires knowledge about the response of engine materials to various service conditions. This paper describes experimental work that studied housing deformation as a result of thermal, pressure and mechanical loads. The measurement of thermal loads, clamping pressure, and deformation was accomplished by use of high-temperature strain gauges, thermocouples, and a high speed data acquisition system. FEM models for heat transfer stress analysis of the rotor housing will be verified and refined based on these experimental results.

Durability and Design Issues of Thermal/environmental Barrier Coatings on Sic/sic Ceramic Matrix Composites Under 1650 C Test Conditions

NASA Technical Reports Server (NTRS)

Zhu, Dong-Ming; Choi, Sung R.; Ghosn, Louis J.; Miller, Robert A.

2004-01-01

Ceramic thermal/environmental barrier coatings for SiC-based ceramics will play an increasingly important role in future gas turbine engines because of their ability to effectively protect the engine components and further raise engine temperatures. However, the coating durability remains a major concern with the ever-increasing temperature requirements. Currently, advanced T/EBC systems, which typically include a high temperature capable zirconia- (or hahia-) based oxide top coat (thermal barrier) on a less temperature capable mullite/barium-strontium-aluminosilicate (BSAS)/Si inner coat (environmental barrier), are being developed and tested for higher temperature capability Sic combustor applications. In this paper, durability of several thermal/environmental barrier coating systems on SiC/SiC ceramic matrix composites was investigated under laser simulated engine thermal gradient cyclic, and 1650 C (3000 F) test conditions. The coating cracking and delamination processes were monitored and evaluated. The effects of temperature gradients and coating configurations on the ceramic coating crack initiation and propagation were analyzed using finite element analysis (FEA) models based on the observed failure mechanisms, in conjunction with mechanical testing results. The environmental effects on the coating durability will be discussed. The coating design approach will also be presented.

Wetland eco-engineering: measuring and modeling feedbacks of oxidation processes between plants and clay-rich material

NASA Astrophysics Data System (ADS)

Saaltink, Rémon; Dekker, Stefan C.; Griffioen, Jasper; Wassen, Martin J.

2016-09-01

Interest is growing in using soft sediment as a foundation in eco-engineering projects. Wetland construction in the Dutch lake Markermeer is an example: here, dredging some of the clay-rich lake-bed sediment and using it to construct wetland will soon begin. Natural processes will be utilized during and after construction to accelerate ecosystem development. Knowing that plants can eco-engineer their environment via positive or negative biogeochemical plant-soil feedbacks, we conducted a 6-month greenhouse experiment to identify the key biogeochemical processes in the mud when Phragmites australis is used as an eco-engineering species. We applied inverse biogeochemical modeling to link observed changes in pore water composition to biogeochemical processes. Two months after transplantation we observed reduced plant growth and shriveling and yellowing of foliage. The N : P ratios of the plant tissue were low, and these were affected not by hampered uptake of N but by enhanced uptake of P. Subsequent analyses revealed high Fe concentrations in the leaves and roots. Sulfate concentrations rose drastically in our experiment due to pyrite oxidation; as reduction of sulfate will decouple Fe-P in reducing conditions, we argue that plant-induced iron toxicity hampered plant growth, forming a negative feedback loop, while simultaneously there was a positive feedback loop, as iron toxicity promotes P mobilization as a result of reduced conditions through root death, thereby stimulating plant growth and regeneration. Given these two feedback mechanisms, we propose the use of Fe-tolerant species rather than species that thrive in N-limited conditions. The results presented in this study demonstrate the importance of studying the biogeochemical properties of the situated sediment and the feedback mechanisms between plant and soil prior to finalizing the design of the eco-engineering project.

A Guide for Using Mechanical Stimulation to Enhance Tissue-Engineered Articular Cartilage Properties.

PubMed

Salinas, Evelia Y; Hu, Jerry C; Athanasiou, Kyriacos

2018-04-26

The use of tissue-engineered articular cartilage (TEAC) constructs has the potential to become a powerful treatment option for cartilage lesions resulting from trauma or early stages of pathology. Although fundamental tissue-engineering strategies based on the use of scaffolds, cells, and signals have been developed, techniques that lead to biomimetic AC constructs that can be translated to in vivo use are yet to be fully confirmed. Mechanical stimulation during tissue culture can be an effective strategy to enhance the mechanical, structural, and cellular properties of tissue-engineered constructs toward mimicking those of native AC. This review focuses on the use of mechanical stimulation to attain and enhance the properties of AC constructs needed to translate these implants to the clinic. In vivo, mechanical loading at maximal and supramaximal physiological levels has been shown to be detrimental to AC through the development of degenerative changes. In contrast, multiple studies have revealed that during culture, mechanical stimulation within narrow ranges of magnitude and duration can produce anisotropic, mechanically robust AC constructs with high cellular viability. Significant progress has been made in evaluating a variety of mechanical stimulation techniques on TEAC, either alone or in combination with other stimuli. These advancements include determining and optimizing efficacious loading parameters (e.g., duration and frequency) to yield improvements in construct design criteria, such as collagen II content, compressive stiffness, cell viability, and fiber organization. With the advancement of mechanical stimulation as a potent strategy in AC tissue engineering, a compendium detailing the results achievable by various stimulus regimens would be of great use for researchers in academia and industry. The objective is to list the qualitative and quantitative effects that can be attained when direct compression, hydrostatic pressure, shear, and tensile loading are used to tissue-engineer AC. Our goal is to provide a practical guide to their use and optimization of loading parameters. For each loading condition, we will also present and discuss benefits and limitations of bioreactor configurations that have been used. The intent is for this review to serve as a reference for including mechanical stimulation strategies as part of AC construct culture regimens.

Blade loss transient dynamics analysis, volume 1. Task 1: Survey and perspective. [aircraft gas turbine engines

NASA Technical Reports Server (NTRS)

Gallardo, V. C.; Gaffney, E. F.; Bach, L. J.; Stallone, M. J.

1981-01-01

An analytical technique was developed to predict the behavior of a rotor system subjected to sudden unbalance. The technique is implemented in the Turbine Engine Transient Rotor Analysis (TETRA) computer program using the component element method. The analysis was particularly aimed toward blade-loss phenomena in gas turbine engines. A dual-rotor, casing, and pylon structure can be modeled by the computer program. Blade tip rubs, Coriolis forces, and mechanical clearances are included. The analytical system was verified by modeling and simulating actual test conditions for a rig test as well as a full-engine, blade-release demonstration.

Man-vehicle systems research facility advanced aircraft flight simulator throttle mechanism

NASA Technical Reports Server (NTRS)

Kurasaki, S. S.; Vallotton, W. C.

1985-01-01

The Advanced Aircraft Flight Simulator is equipped with a motorized mechanism that simulates a two engine throttle control system that can be operated via a computer driven performance management system or manually by the pilots. The throttle control system incorporates features to simulate normal engine operations and thrust reverse and vary the force feel to meet a variety of research needs. While additional testing to integrate the work required is principally now in software design, since the mechanical aspects function correctly. The mechanism is an important part of the flight control system and provides the capability to conduct human factors research of flight crews with advanced aircraft systems under various flight conditions such as go arounds, coupled instrument flight rule approaches, normal and ground operations and emergencies that would or would not normally be experienced in actual flight.

The Effect of Ethanol Addition to Gasoline on Low- and Intermediate-Temperature Heat Release under Boosted Conditions in Kinetically Controlled Engines

NASA Astrophysics Data System (ADS)

Vuilleumier, David Malcolm

The detailed study of chemical kinetics in engines has become required to further advance engine efficiency while simultaneously lowering engine emissions. This push for higher efficiency engines is not caused by a lack of oil, but by efforts to reduce anthropogenic carbon dioxide emissions, that cause global warming. To operate in more efficient manners while reducing traditional pollutant emissions, modern internal combustion piston engines are forced to operate in regimes in which combustion is no longer fully transport limited, and instead is at least partially governed by chemical kinetics of combusting mixtures. Kinetically-controlled combustion allows the operation of piston engines at high compression ratios, with partially-premixed dilute charges; these operating conditions simultaneously provide high thermodynamic efficiency and low pollutant formation. The investigations presented in this dissertation study the effect of ethanol addition on the low-temperature chemistry of gasoline type fuels in engines. These investigations are carried out both in a simplified, fundamental engine experiment, named Homogeneous Charge Compression Ignition, as well as in more applied engine systems, named Gasoline Compression Ignition engines and Partial Fuel Stratification engines. These experimental investigations, and the accompanying modeling work, show that ethanol is an effective scavenger of radicals at low temperatures, and this inhibits the low temperature pathways of gasoline oxidation. Further, the investigations measure the sensitivity of gasoline auto-ignition to system pressure at conditions that are relevant to modern engines. It is shown that at pressures above 40 bar and temperatures below 850 Kelvin, gasoline begins to exhibit Low-Temperature Heat Release. However, the addition of 20% ethanol raises the pressure requirement to 60 bar, while the temperature requirement remains unchanged. These findings have major implications for a range of modern engines. Low-Temperature Heat Release significantly enhances the auto-ignition process, which limits the conditions under which advanced combustion strategies may operate. As these advanced combustion strategies are required to meet emissions and fuel-economy regulations, the findings of this dissertation may benefit and be incorporated into future engine design toolkits, such as detailed chemical kinetic mechanisms.

Study of a LH2-fueled topping cycle engine for aircraft propulsion

NASA Technical Reports Server (NTRS)

Turney, G. E.; Fishbach, L. H.

1983-01-01

An analytical investigation was made of a topping cycle aircraft engine system which uses a cryogenic fuel. This system consists of a main turboshaft engine which is mechanically coupled (by cross-shafting) to a topping loop which augments the shaft power output of the system. The thermodynamic performance of the topping cycle engine was analyzed and compared with that of a reference (conventional-type) turboshaft engine. For the cycle operating conditions selected, the performance of the topping cycle engine in terms of brake specific fuel consumption (bsfc) was determined to be about 12 percent better than that of the reference turboshaft engine. Engine weights were estimated for both the topping cycle engine and the reference turboshaft engine. These estimates were based on a common shaft power output for each engine. Results indicate that the weight of the topping cycle engine is comparable to that of the reference turboshaft engine. Previously announced in STAR as N83-34942

Procedure for developing experimental designs for accelerated tests for service-life prediction. [for solar cell modules

NASA Technical Reports Server (NTRS)

Thomas, R. E.; Gaines, G. B.

1978-01-01

Recommended design procedures to reduce the complete factorial design by retaining information on anticipated important interaction effects, and by generally giving up information on unconditional main effects are discussed. A hypothetical photovoltaic module used in the test design is presented. Judgments were made of the relative importance of various environmental stresses such as UV radiation, abrasion, chemical attack, temperature, mechanical stress, relative humidity and voltage. Consideration is given to a complete factorial design and its graphical representation, elimination of selected test conditions, examination and improvement of an engineering design, and parametric study. The resulting design consists of a mix of conditional main effects and conditional interactions and represents a compromise between engineering and statistical requirements.

Evaluation of Separation Mechanism Design for the Orion/Ares Launch Vehicle

NASA Technical Reports Server (NTRS)

Konno, Kevin E.; Catalano, Daniel A.; Krivanek, Thomas M.

2008-01-01

As a part of the preliminary design work being performed for the Orion vehicle, the Orion to Spacecraft Adaptor (SA) separation mechanism mechanism was analyzed and sized, with findings presented here. Sizing is based on worst case abort condition as a result of an anomaly driving the launch vehicle engine thrust vector control hard-over causing a severe vehicle pitch over. This worst case scenario occurs just before Upper Stage Main Engine Cut-Off (MECO) when the vehicle is the lightest and the damping effect due to propellant slosh has been reduced to a minimum. To address this scenario and others, two modeling approaches were invoked. The first approach was a detailed Simulink model to quickly assess the Service Module Engine nozzle to SA clearance for a given separation mechanism. The second approach involved the generation of an Automatic Dynamic Analysis of Mechanical Systems (ADAMS) model to assess secondary effects due to mass centers of gravity that were slightly off the vehicle centerline. It also captured any interference between the Solar Arrays and the Spacecraft Adapter. A comparison of modeling results and accuracy are discussed. Most notably, incorporating a larger SA flange diameter allowed for a natural separation of the Orion and its engine nozzle even at relatively large pitch rates minimizing the kickoff force. Advantages and disadvantages of the Simulink model vs. a full geometric ADAMS model are discussed as well.

Research on EHN additive on the diesel engine combustion characteristics in plateau environment

NASA Astrophysics Data System (ADS)

Sun, Zhixin; Li, Ruoting; Wang, Xiancheng; Hu, Chuan

2017-03-01

Aiming at the combustion deterioration problem of diesel engine in plateau environment, a bench test was carried out for the effects of EHN additive on combustion characteristics of the diesel engine with intake pressure of 0.68 kPa. Test results showed that with the full load working condition of 1 400 r/min: Cylinder pressure and pressure uprising rate decreased with EHN additive added in, mechanical load on the engine could be relieved; peak value of the heat release rate decreased and its occurrence advanced, ignition delay and combustion duration were shortened; cylinder temperature and exhaust gas temperature declined, thermal load on the engine could be relieved, output torque increased while specific oil consumption decreased, and effective thermal efficiency of diesel engine increased.

Living nanofiber yarn-based woven biotextiles for tendon tissue engineering using cell tri-culture and mechanical stimulation.

PubMed

Wu, Shaohua; Wang, Ying; Streubel, Philipp N; Duan, Bin

2017-10-15

Non-woven nanofibrous scaffolds have been developed for tendon graft application by using electrospinning strategies. However, electrospun nanofibrous scaffolds face some obstacles and limitations, including suboptimal scaffold structure, weak tensile and suture-retention strengths, and compact structure for cell infiltration. In this work, a novel nanofibrous, woven biotextile, fabricated based on electrospun nanofiber yarns, was implemented as a tissue engineered tendon scaffold. Based on our modified electrospinning setup, polycaprolactone (PCL) nanofiber yarns were fabricated with reproducible quality, and were further processed into plain-weaving fabrics interlaced with polylactic acid (PLA) multifilaments. Nonwoven nanofibrous PCL meshes with random or aligned fiber structures were generated using typical electrospinning as comparative counterparts. The woven fabrics contained 3D aligned microstructures with significantly larger pore size and obviously enhanced tensile mechanical properties than their nonwoven counterparts. The biological results revealed that cell proliferation and infiltration, along with the expression of tendon-specific genes by human adipose derived mesenchymal stem cells (HADMSC) and human tenocytes (HT), were significantly enhanced on the woven fabrics compared with those on randomly-oriented or aligned nanofiber meshes. Co-cultures of HADMSC with HT or human umbilical vein endothelial cells (HUVEC) on woven fabrics significantly upregulated the functional expression of most tenogenic markers. HADMSC/HT/HUVEC tri-culture on woven fabrics showed the highest upregulation of most tendon-associated markers than all the other mono- and co-culture groups. Furthermore, we conditioned the tri-cultured constructs with dynamic conditioning and demonstrated that dynamic stretch promoted total collagen secretion and tenogenic differentiation. Our nanofiber yarn-based biotextiles have significant potential to be used as engineered scaffolds to synergize the multiple cell interaction and mechanical stimulation for promoting tendon regeneration. Tendon grafts are essential for the treatment of various tendon-related conditions due to the inherently poor healing capacity of native tendon tissues. In this study, we combined electrospun nanofiber yarns with textile manufacturing strategies to fabricate nanofibrous woven biotextiles with hierarchical features, aligned fibrous topography, and sufficient mechanical properties as tendon tissue engineered scaffolds. Comparing to traditional electrospun random or aligned meshes, our novel nanofibrous woven fabrics possess strong tensile and suture-retention strengths and larger pore size. We also demonstrated that the incorporation of tendon cells and vascular cells promoted the tenogenic differentiation of the engineered tendon constructs, especially under dynamic stretch. This study not only presents a novel tissue engineered tendon scaffold fabrication technique but also provides a useful strategy to promote tendon differentiation and regeneration. Copyright © 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

Chondroprotective supplementation promotes the mechanical properties of injectable scaffold for human nucleus pulposus tissue engineering.

PubMed

Foss, Berit L; Maxwell, Thomas W; Deng, Ying

2014-01-01

A result of intervertebral disc (IVD) degeneration, the nucleus pulposus (NP) is no longer able to withstand applied load leading to pain and disability. The objective of this study is to fabricate a tissue-engineered injectable scaffold with chondroprotective supplementation in vitro to improve the mechanical properties of a degenerative NP. Tissue-engineered scaffolds were fabricated using different concentrations of alginate and calcium chloride and mechanically evaluated. Fabrication conditions were based on structural and mechanical resemblance to the native NP. Chondroprotective supplementation, glucosamine (GCSN) and chondroitin sulfate (CS), were added to scaffolds at concentrations of 0:0µg/mL (0:0-S), 125:100µg/mL (125:100-S), 250:200µg/mL (250:200-S), and 500:400µg/mL (500:400-S), GCSN and CS, respectively. Scaffolds were used to fabricate tissue-engineered constructs through encapsulation of human nucleus pulposus cells (HNPCs). The tissue-engineered constructs were collected at days 1, 14, and 28 for biochemical and biomechanical evaluations. Confocal microscopy showed HNPC viability and rounded morphology over the 28 day period. MTT analysis resulted in significant increases in cell proliferation for each group. Collagen type II ELISA quantification and compressive aggregate moduli (HA) showed increasing trends for both 250:200-S and the 500:400-S groups on Day 28 with significantly greater HA compared to 0:0-S group. Glycosaminoglycan and water content decreased for all groups. Results indicate the increased mechanical properties of the 250:200-S and the 500:400-S was due to production of a functional matrix. This study demonstrated potential for a chondroprotective supplemented injectable scaffold to restore biomechanical function of a degenerative disc through the production of a mechanically functional matrix. Copyright © 2013 Elsevier Ltd. All rights reserved.

Do-It-Yourself Additives Recharge Auto Air Conditioning

NASA Technical Reports Server (NTRS)

2010-01-01

In planning for a return mission to the Moon, NASA aimed to improve the thermal control systems that keep astronauts comfortable and cool while inside a spacecraft. Goddard Space Flight Center awarded a Small Business Innovation Research (SBIR) contract to Mainstream Engineering Corporation, of Rockledge, Florida, to develop a chemical/mechanical heat pump. IDQ Inc., of Garland, Texas, exclusively licensed the technology and incorporates it into its line of Arctic Freeze products for automotive air conditioning applications. While working on the design, Mainstream Engineering came up with a unique liquid additive called QwikBoost to enhance the performance of the advanced heat pump design.

Tissue engineering therapy for cardiovascular disease.

PubMed

Nugent, Helen M; Edelman, Elazer R

2003-05-30

The present treatments for the loss or failure of cardiovascular function include organ transplantation, surgical reconstruction, mechanical or synthetic devices, or the administration of metabolic products. Although routinely used, these treatments are not without constraints and complications. The emerging and interdisciplinary field of tissue engineering has evolved to provide solutions to tissue creation and repair. Tissue engineering applies the principles of engineering, material science, and biology toward the development of biological substitutes that restore, maintain, or improve tissue function. Progress has been made in engineering the various components of the cardiovascular system, including blood vessels, heart valves, and cardiac muscle. Many pivotal studies have been performed in recent years that may support the move toward the widespread application of tissue-engineered therapy for cardiovascular diseases. The studies discussed include endothelial cell seeding of vascular grafts, tissue-engineered vascular conduits, generation of heart valve leaflets, cardiomyoplasty, genetic manipulation, and in vitro conditions for optimizing tissue-engineered cardiovascular constructs.

USAF Summer Research Program - 1993 Graduate Student Research Program Final Reports, Volume 6, AEDC, FJSRL and WHMC

DTIC Science & Technology

1993-12-01

Mechanical Engineering Associate, PhD Laboratory: PL/VT Division Engineering University of Texas, San Anton Vol-Page No: 3-26 San Antonio, TX 7824-9065...parameters. The modules can be primitive or compound. Primitive modules represent the elementary computation units and define their interfaces. The... linear under varying conditions for the range of processor numbers. Discussion Performance: Our evaluation of the performance measurement results is the

Design considerations and challenges for mechanical stretch bioreactors in tissue engineering.

PubMed

Lei, Ying; Ferdous, Zannatul

2016-05-01

With the increase in average life expectancy and growing aging population, lack of functional grafts for replacement surgeries has become a severe problem. Engineered tissues are a promising alternative to this problem because they can mimic the physiological function of the native tissues and be cultured on demand. Cyclic stretch is important for developing many engineered tissues such as hearts, heart valves, muscles, and bones. Thus a variety of stretch bioreactors and corresponding scaffolds have been designed and tested to study the underlying mechanism of tissue formation and to optimize the mechanical conditions applied to the engineered tissues. In this review, we look at various designs of stretch bioreactors and common scaffolds and offer insights for future improvements in tissue engineering applications. First, we summarize the requirements and common configuration of stretch bioreactors. Next, we present the features of different actuating and motion transforming systems and their applications. Since most bioreactors must measure detailed distributions of loads and deformations on engineered tissues, techniques with high accuracy, precision, and frequency have been developed. We also cover the key points in designing culture chambers, nutrition exchanging systems, and regimens used for specific tissues. Since scaffolds are essential for providing biophysical microenvironments for residing cells, we discuss materials and technologies used in fabricating scaffolds to mimic anisotropic native tissues, including decellularized tissues, hydrogels, biocompatible polymers, electrospinning, and 3D bioprinting techniques. Finally, we present the potential future directions for improving stretch bioreactors and scaffolds. © 2016 American Institute of Chemical Engineers Biotechnol. Prog., 32:543-553, 2016. © 2016 American Institute of Chemical Engineers.

Pulsatile perfusion bioreactor for cardiac tissue engineering.

PubMed

Brown, Melissa A; Iyer, Rohin K; Radisic, Milica

2008-01-01

Cardiovascular disease is the number one cause of mortality in North America. Cardiac tissue engineering aims to engineer a contractile patch of physiological thickness to use in surgical repair of diseased heart tissue. We previously reported that perfusion of engineered cardiac constructs resulted in improved tissue assembly. Because heart tissues respond to mechanical stimuli in vitro and experience rhythmic mechanical forces during contraction in vivo, we hypothesized that provision of pulsatile interstitial medium flow to an engineered cardiac patch would result in enhanced tissue assembly by way of mechanical conditioning and improved mass transport. Thus, we constructed a novel perfusion bioreactor capable of providing pulsatile fluid flow at physiologically relevant shear stresses and flow rates. Pulsatile perfusion (PP) was achieved by incorporation of a normally closed solenoid pinch valve into the perfusion loop and was carried out at a frequency of 1 Hz and a flow rate of 1.50 mL/min (PP) or 0.32 mL/min (PP-LF). Nonpulsatile flow at 1.50 mL/min (NP) or 0.32 mL/min (NP-LF) served as controls. Static controls were cultivated in well plates. The main experimental groups were seeded with cells enriched for cardiomyocytes by one preplating step (64% cardiac Troponin I+, 34% prolyl-4-hydroxylase+), whereas pure cardiac fibroblasts and cells enriched for cardiomyocytes by two preplating steps (81% cardiac Troponin I+, 16% prolyl-4-hydroxylase+) served as controls. Cultivation under pulsatile flow had beneficial effects on contractile properties. Specifically, the excitation threshold was significantly lower in the PP condition (pulsatile perfusion at 1.50 mL/min) than in the Static control, and the contraction amplitude was the highest; whereas high maximum capture rate was observed for the PP-LF conditions (pulsatile perfusion at 0.32 mL/min). The enhanced hypertrophy index observed for the PP-LF group was consistent with the highest cellular length and diameter in this group. Within the same cultivation groups (Static, NP-LF, PP-LF, PP, and NP) there were no significant differences in the diameter between fibroblasts and cardiomyocytes, although cardiomyocytes were significantly more elongated than fibroblasts under PP-LF conditions. Cultivation of control cell populations resulted in noncontractile constructs when cardiac fibroblasts were used (as expected) and no overall improvement in functional properties when two steps of preplating were used to enrich for cardiomyocytes in comparison with only one step of preplating.

Engineering a degradable polyurethane intravaginal ring for sustained delivery of dapivirine.

PubMed

Kaur, Manpreet; Gupta, Kavita M; Poursaid, Azadeh E; Karra, Prasoona; Mahalingam, Alamelu; Aliyar, Hyder A; Kiser, Patrick F

2011-06-01

We describe the engineering of a degradable intravaginal ring (IVR) for the delivery of the potent HIV-1 reverse transcriptase inhibitor dapivirine. The degradable polymer used in fabricating the device incorporated poly(caprolactone) ester blocks in a poly(tetramethylene ether) glycol ABA type polyurethane backbone. The polymer was designed to maintain its structure for 1 month during usage and then degrade in the environment post-disposal. In vitro release of dapivirine showed zero-order kinetics for up to 1 month and significant levels of drug release into engineered vaginal tissue. The mechanical properties of the degradable IVR were comparable to those of a widely used contraceptive intravaginal ring upon exposure to simulated vaginal conditions. Incubation under simulated vaginal conditions for a month caused minimal degradation with minimal effect on the mechanical properties of the ring and polymer. The cytotoxicity evaluation of the drug-loaded IVRs against Vk2/E6E7 human vaginal epithelial cells, Lactobacillus jensenii, and engineered vaginal tissue constructs showed the degradable polyurethane to be non-toxic. In vitro evaluation of inflammatory potential monitored through the levels of inflammatory cytokines IL-8, IL-1α, IL-6, IL-1β, and MIP-3α when engineered EpiVaginal™ tissue was incubated with the polyurethanes suggested that the degradable polyurethane was comparable to commercial medical grade polyurethane. These results are encouraging for further development of this degradable IVR for topical vaginal delivery of microbicides.

Combustion Stability Verification for the Thrust Chamber Assembly of J-2X Developmental Engines 10001, 10002, and 10003

NASA Technical Reports Server (NTRS)

Morgan, C. J.; Hulka, J. R.; Casiano, M. J.; Kenny, R. J.; Hinerman, T. D.; Scholten, N.

2015-01-01

The J-2X engine, a liquid oxygen/liquid hydrogen propellant rocket engine available for future use on the upper stage of the Space Launch System vehicle, has completed testing of three developmental engines at NASA Stennis Space Center. Twenty-one tests of engine E10001 were conducted from June 2011 through September 2012, thirteen tests of the engine E10002 were conducted from February 2013 through September 2013, and twelve tests of engine E10003 were conducted from November 2013 to April 2014. Verification of combustion stability of the thrust chamber assembly was conducted by perturbing each of the three developmental engines. The primary mechanism for combustion stability verification was examining the response caused by an artificial perturbation (bomb) in the main combustion chamber, i.e., dynamic combustion stability rating. No dynamic instabilities were observed in the TCA, although a few conditions were not bombed. Additional requirements, included to guard against spontaneous instability or rough combustion, were also investigated. Under certain conditions, discrete responses were observed in the dynamic pressure data. The discrete responses were of low amplitude and posed minimal risk to safe engine operability. Rough combustion analyses showed that all three engines met requirements for broad-banded frequency oscillations. Start and shutdown transient chug oscillations were also examined to assess the overall stability characteristics, with no major issues observed.

Grain Boundary Engineering the Mechanical Properties of Allvac 718Plus(Trademark) Superalloy

NASA Technical Reports Server (NTRS)

Gabb, Timothy P.; Telesman, Jack; Garg, Anita; Lin, Peter; Provenzano, virgil; Heard, Robert; Miller, Herbert M.

2010-01-01

Grain Boundary Engineering can enhance the population of structurally-ordered "low S" Coincidence Site Lattice (CSL) grain boundaries in the microstructure. In some alloys, these "special" grain boundaries have been reported to improve overall resistance to corrosion, oxidation, and creep resistance. Such improvements could be quite beneficial for superalloys, especially in conditions which encourage damage and cracking at grain boundaries. Therefore, the effects of GBE processing on high-temperature mechanical properties of the cast and wrought superalloy Allvac 718Plus (Allvac ATI) were screened. Bar sections were subjected to varied GBE processing, and then consistently heat treated, machined, and tested at 650 C. Creep, tensile stress relaxation, and dwell fatigue crack growth tests were performed. The influences of GBE processing on microstructure, mechanical properties, and associated failure modes are discussed.

Genetically Engineered Mouse Models for Studying Inflammatory Bowel Disease

PubMed Central

Mizoguchi, Atsushi; Takeuchi, Takahito; Himuro, Hidetomo; Okada, Toshiyuki; Mizoguchi, Emiko

2015-01-01

Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory condition that is mediated by very complex mechanisms controlled by genetic, immune, and environmental factors. More than 74 kinds of genetically engineered mouse strains have been established since 1993 for studying IBD. Although mouse models cannot fully reflect human IBD, they have provided significant contributions for not only understanding the mechanism, but also developing new therapeutic means for IBD. Indeed, 20 kinds of genetically engineered mouse models carry the susceptibility genes identified in human IBD, and the functions of some other IBD susceptibility genes have also been dissected out using mouse models. Cutting-edge technologies such as cell-specific and inducible knockout systems, which were recently employed to mouse IBD models, have further enhanced the ability of investigators to provide important and unexpected rationales for developing new therapeutic strategies for IBD. In this review article, we briefly introduce 74 kinds of genetically engineered mouse models that spontaneously develop intestinal inflammation. PMID:26387641

Creep, Fatigue and Fracture Behavior of Environmental Barrier Coating and SiC-SiC Ceramic Matrix Composite Systems: The Role of Environment Effects

NASA Technical Reports Server (NTRS)

Zhu, Dongming; Ghosn, Louis J.

2015-01-01

Advanced environmental barrier coating (EBC) systems for low emission SiCSiC CMC combustors and turbine airfoils have been developed to meet next generation engine emission and performance goals. This presentation will highlight the developments of NASAs current EBC system technologies for SiC-SiC ceramic matrix composite combustors and turbine airfoils, their performance evaluation and modeling progress towards improving the engine SiCSiC component temperature capability and long-term durability. Our emphasis has also been placed on the fundamental aspects of the EBC-CMC creep and fatigue behaviors, and their interactions with turbine engine oxidizing and moisture environments. The EBC-CMC environmental degradation and failure modes, under various simulated engine testing environments, in particular involving high heat flux, high pressure, high velocity combustion conditions, will be discussed aiming at quantifying the protective coating functions, performance and durability, and in conjunction with damage mechanics and fracture mechanics approaches.

Experimental study on mechanism and shape characteristics of suspended flexible dam

NASA Astrophysics Data System (ADS)

Wang, Jian-zhong; Fan, Hong-xia; Zhu, Li-jun

2014-12-01

Hydraulic structures such as groin, longitudinal dike and seawall are common in water conservancy and water transportation engineering projects at home and abroad, which have long been dominated by solid mass structural form. With brush and stone as building materials, this kind of structure has an obvious engineering effect. However, it not only requires huge capital investments, but also has negative impacts on the ecological environment. The suspended flexible dam is an innovative engineering measure, and few theoretical and experimental researches of this type dam can be found at present. This paper studies the mechanism and shape characteristics of this dam and obtains the dynamic equilibrium equation of flexible dam, the float buoyancy expression, and the condition for transformation among three forms of the underwater shape of the dam. The results are valuable in engineering application and can be used as the reference for the future work due to the distinctive design philosophy, the small negative effects on environment and the consistency for sustainable development.

Extreme mechanical properties of materials under extreme pressure and temperature conditions (Invited)

NASA Astrophysics Data System (ADS)

Kavner, A.; Armentrout, M. M.; Xie, M.; Weinberger, M.; Kaner, R. B.; Tolbert, S. H.

2010-12-01

A strong synergy ties together the high-pressure subfields of mineral physics, solid-state physics, and materials engineering. The catalog of studies measuring the mechanical properties of materials subjected to large differential stresses in the diamond anvil cell demonstrates a significant pressure-enhancement of strength across many classes of materials, including elemental solids, salts, oxides, silicates, and borides and nitrides. High pressure techniques—both radial diffraction and laser heating in the diamond anvil cell—can be used to characterize the behavior of ultrahard materials under extreme conditions, and help test hypotheses about how composition, structure, and bonding work together to govern the mechanical properties of materials. The principles that are elucidated by these studies can then be used to help design engineering materials to encourage desired properties. Understanding Earth and planetary interiors requires measuring equations of state of relevant materials, including oxides, silicates, and metals under extreme conditions. If these minerals in the diamond anvil cell have any ability to support a differential stress, the assumption of quasi-hydrostaticity no longer applies, with a resulting non-salubrious effect on attempts to measure equation of state. We illustrate these applications with the results of variety of studies from our laboratory and others’ that have used high-pressure radial diffraction techniques and also laser heating in the diamond anvil cell to characterize the mechanical properties of a variety of ultrahard materials, especially osmium metal, osmium diboride, rhenium diboride, and tungsten tetraboride. We compare ambient condition strength studies such as hardness testing with high-pressure studies, especially radial diffraction under differential stress. In addition, we outline criteria for evaluating mechanical properties of materials at combination high pressures and temperatures. Finally, we synthesize our understanding of mechanical properties and composite behavior to suggest new approaches to designing high-pressure experiments to target specific measurements of a wide variety of mechanical properties.

Dynamic culture yields engineered myocardium with near-adult functional output

PubMed Central

Jackman, Christopher P.; Carlson, Aaron L.; Bursac, Nenad

2016-01-01

Engineered cardiac tissues hold promise for cell therapy and drug development, but exhibit inadequate function and maturity. In this study, we sought to significantly improve the function and maturation of rat and human engineered cardiac tissues. We developed dynamic, free-floating culture conditions for engineering “cardiobundles”, 3-dimensional cylindrical tissues made from neonatal rat cardiomyocytes or human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) embedded in fibrin-based hydrogel. Compared to static culture, 2-week dynamic culture of neonatal rat cardiobundles significantly increased expression of sarcomeric proteins, cardiomyocyte size (~2.1-fold), contractile force (~3.5-fold), and conduction velocity of action potentials (~1.4-fold). The average contractile force per cross-sectional area (59.7 mN/mm2) and conduction velocity (52.5 cm/sec) matched or approached those of adult rat myocardium, respectively. The inferior function of statically cultured cardiobundles was rescued by transfer to dynamic conditions, which was accompanied by an increase in mTORC1 activity and decline in AMPK phosphorylation and was blocked by rapamycin. Furthermore, dynamic culture effects did not stimulate ERK1/2 pathway and were insensitive to blockers of mechanosensitive channels, suggesting increased nutrient availability rather than mechanical stimulation as the upstream activator of mTORC1. Direct comparison with phenylephrine treatment confirmed that dynamic culture promoted physiological cardiomyocyte growth rather than pathological hypertrophy. Optimized dynamic culture conditions also augmented function of human cardiobundles made reproducibly from cardiomyocytes derived from multiple hPSC lines, resulting in significantly increased contraction force (~2.5-fold) and conduction velocity (~1.4-fold). The average specific force of 23.2 mN/mm2 and conduction velocity of 25.8 cm/sec approached the functional metrics of adult human myocardium. In conclusion, we have developed a versatile methodology for engineering cardiac tissues with a near-adult functional output without the need for exogenous electrical or mechanical stimulation, and have identified mTOR signaling as an important mechanism for advancing tissue maturation and function in vitro. PMID:27723557

Dynamic culture yields engineered myocardium with near-adult functional output.

PubMed

Jackman, Christopher P; Carlson, Aaron L; Bursac, Nenad

2016-12-01

Engineered cardiac tissues hold promise for cell therapy and drug development, but exhibit inadequate function and maturity. In this study, we sought to significantly improve the function and maturation of rat and human engineered cardiac tissues. We developed dynamic, free-floating culture conditions for engineering "cardiobundles", 3-dimensional cylindrical tissues made from neonatal rat cardiomyocytes or human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) embedded in fibrin-based hydrogel. Compared to static culture, 2-week dynamic culture of neonatal rat cardiobundles significantly increased expression of sarcomeric proteins, cardiomyocyte size (∼2.1-fold), contractile force (∼3.5-fold), and conduction velocity of action potentials (∼1.4-fold). The average contractile force per cross-sectional area (59.7 mN/mm 2 ) and conduction velocity (52.5 cm/s) matched or approached those of adult rat myocardium, respectively. The inferior function of statically cultured cardiobundles was rescued by transfer to dynamic conditions, which was accompanied by an increase in mTORC1 activity and decline in AMPK phosphorylation and was blocked by rapamycin. Furthermore, dynamic culture effects did not stimulate ERK1/2 pathway and were insensitive to blockers of mechanosensitive channels, suggesting increased nutrient availability rather than mechanical stimulation as the upstream activator of mTORC1. Direct comparison with phenylephrine treatment confirmed that dynamic culture promoted physiological cardiomyocyte growth rather than pathological hypertrophy. Optimized dynamic culture conditions also augmented function of human cardiobundles made reproducibly from cardiomyocytes derived from multiple hPSC lines, resulting in significantly increased contraction force (∼2.5-fold) and conduction velocity (∼1.4-fold). The average specific force of 23.2 mN/mm 2 and conduction velocity of 25.8 cm/s approached the functional metrics of adult human myocardium. In conclusion, we have developed a versatile methodology for engineering cardiac tissues with a near-adult functional output without the need for exogenous electrical or mechanical stimulation, and have identified mTOR signaling as an important mechanism for advancing tissue maturation and function in vitro. Copyright © 2016 Elsevier Ltd. All rights reserved.

Defining Medical Capabilities for Exploration Missions

NASA Technical Reports Server (NTRS)

Hailey, M.; Antonsen, E.; Blue, R.; Reyes, D.; Mulcahy, R.; Kerstman, E.; Bayuse, T.

2018-01-01

Exploration-class missions to the moon, Mars and beyond will require a significant change in medical capability from today's low earth orbit centric paradigm. Significant increases in autonomy will be required due to differences in duration, distance and orbital mechanics. Aerospace medicine and systems engineering teams are working together within ExMC to meet these challenges. Identifying exploration medical system needs requires accounting for planned and unplanned medical care as defined in the concept of operations. In 2017, the ExMC Clinicians group identified medical capabilities to feed into the Systems Engineering process, including: determining what and how to address planned and preventive medical care; defining an Accepted Medical Condition List (AMCL) of conditions that may occur and a subset of those that can be treated effectively within the exploration environment; and listing the medical capabilities needed to treat those conditions in the AMCL. This presentation will discuss the team's approach to addressing these issues, as well as how the outputs of the clinical process impact the systems engineering effort.

The research Of Multilayer Thermal Insulation With Mechanical Properties Based On Model Analysis Test

NASA Astrophysics Data System (ADS)

Lianhua, Yin

The heat shield of aircraft is made of the major thrusts structure with multilayer thermal insulation part. For protecting against thermo-radiation from larger thrusting force engine,the heat shield is installed around this engine nearby.The multilayer thermal insulation part with multilayer radiation/reflection structure is made of reflection layer and interval layer.At vacuum condition,these materials is higher heat insulation capability than other material,is applied for lots of pats on aircraft extensively.But because of these material is made of metal and nonmetal,it is impossible to receive it's mechanical properties of materials from mechanical tests.These paper describes a new measure of mechanical properties of materials in the heat shield based on model analysis test.At the requirement for the first order lateral frequency,these measure provide for the FEM analysis foundation on the optimization structure of the heat shield.

Performance and Durability of Environmental Barrier Coatings on SiC/SiC Ceramic Matrix Composites

NASA Technical Reports Server (NTRS)

Zhu, Dongming; Harder, Bryan; Bhatt, Ramakrishna

2016-01-01

This presentation highlights advanced environmental barrier coating (EBC) and SiC-SiC Ceramic Matrix Composites (CMC) systems for next generation turbine engines. The emphasis will be placed on fundamental coating and CMC property evaluations; and the integrated system performance and degradation mechanisms in simulated laboratory turbine engine testing environments. Long term durability tests in laser rig simulated high heat flux the rmomechanical creep and fatigue loading conditions will also be presented. The results can help improve the future EBC-CMC system designs, validating the advanced EBC-CMC technologies for hot section turbine engine applications.

Effect of design over-all compressor pressure ratio division on acceleration characteristics of three hypothetical two-spool turbojet engines

NASA Technical Reports Server (NTRS)

Filippi, Richard E; Dugan, James F , Jr

1956-01-01

The engines, each with a compressor overall total-pressure ratio of 12 and a design inner-turbine-inlet temperature of 2500 degrees R, were investigated at static sea-level conditions to determine the effect on transient performance of varying the desitn pressure ratio divisions 2-6, 3-4, and 4-3 between the outer and inner compressors. The transient considered was an acceleration from 40 to 100 percent design thrust. When the outer compressor of each engine reached design speed, the inner compressors were overspeeding, the maximum being only 1.7 over design mechanical speed. Acceleration times for the three engines were equal.

46 CFR 110.30-5 - Inspection for certification.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING GENERAL PROVISIONS Testing and Inspection § 110.30-5 Inspection for certification. Electric installations and electric... mechanical and electrical condition and performance. Particular note must be made of circuits added or...

46 CFR 110.30-5 - Inspection for certification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING GENERAL PROVISIONS Testing and Inspection § 110.30-5 Inspection for certification. Electric installations and electric... mechanical and electrical condition and performance. Particular note must be made of circuits added or...

46 CFR 110.30-5 - Inspection for certification.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING GENERAL PROVISIONS Testing and Inspection § 110.30-5 Inspection for certification. Electric installations and electric... mechanical and electrical condition and performance. Particular note must be made of circuits added or...

Intelligent Mining Engineering Systems in the Structure of Industry 4.0

NASA Astrophysics Data System (ADS)

Rylnikova, Marina; Radchenko, Dmitriy; Klebanov, Dmitriy

2017-11-01

The solution of the problem of improving the human environment and working conditions at mines is based on the provision of the rationale of parameters and conditions for the implementation of an environmentally balanced cycle of comprehensive development of mineral deposits on the basis of the design of mining engineering systems characterized by the minimization of the human factor effect in danger zones of mining operations. In this area, robotized technologies are being developed, machinery and mechanisms with the elements of artificial intelligence, and mining and transport system automatic controls are being put into service throughout the world. In the upcoming decades, mining machines and mechanisms will be virtually industrial robots. The article presents the results of zoning of open-pit and underground mine production areas, as well as mining engineering system of combined development depending on the fact and periodicity of human presence in zones of mining processes. As a surface geotechnology case study, the software structure based on a modular concept is described. The performance philosophy of mining and transport equipment with the elements of artificial intelligence is shown when it is put into service in an open pit.

Engineering principles to assure compatible docking between future spacecraft of USA and USSR

NASA Technical Reports Server (NTRS)

Johnson, C. C.

1973-01-01

An androgynous peripheral type docking mechanism concept selected by the U.S. and the USSR is described. The rationale supporting the selection of the concept, the mechanical principles inherent to the concept, and the probable nature of future designs stemming from the concept are discussed. Operational situations prior to docking, impact conditions, energy absorption, and structural joining of two spacecraft are examined.

Discussion of the Investigation Method on the Reaction Kinetics of Metallurgical Reaction Engineering

NASA Astrophysics Data System (ADS)

Du, Ruiling; Wu, Keng; Zhang, Jiazhi; Zhao, Yong

Reaction kinetics of metallurgical physical chemistry which was successfully applied in metallurgy (as ferrous metallurgy, non-ferrous metallurgy) became an important theoretical foundation for subject system of traditional metallurgy. Not only the research methods were very perfect, but also the independent structures and systems of it had been formed. One of the important tasks of metallurgical reaction engineering was the simulation of metallurgical process. And then, the mechanism of reaction process and the conversion time points of different control links should be obtained accurately. Therefore, the research methods and results of reaction kinetics in metallurgical physical chemistry were not very suitable for metallurgical reaction engineering. In order to provide the definite conditions of transmission, reaction kinetics parameters and the conversion time points of different control links for solving the transmission and reaction equations in metallurgical reaction engineering, a new method for researching kinetics mechanisms in metallurgical reaction engineering was proposed, which was named stepwise attempt method. Then the comparison of results between the two methods and the further development of stepwise attempt method were discussed in this paper. As a new research method for reaction kinetics in metallurgical reaction engineering, stepwise attempt method could not only satisfy the development of metallurgical reaction engineering, but also provide necessary guarantees for establishing its independent subject system.

Design and Use of a Novel Bioreactor for Regeneration of Biaxially Stretched Tissue-Engineered Vessels

PubMed Central

Huang, Angela Hai; Lee, Yong-Ung; Calle, Elizabeth A.; Boyle, Michael; Starcher, Barry C.; Humphrey, Jay D.

2015-01-01

Conventional bioreactors are used to enhance extracellular matrix (ECM) production and mechanical strength of tissue-engineered vessels (TEVs) by applying circumferential strain, which is uniaxial stretching. However, the resulting TEVs still suffer from inadequate mechanical properties, where rupture strengths and compliance values are still very different from native arteries. The biomechanical milieu of native arteries consists of both circumferential and axial loading. Therefore, to better simulate the physiological stresses acting on native arteries, we built a novel bioreactor system to enable biaxial stretching of engineered arteries during culture. This new bioreactor system allows for independent control of circumferential and axial stretching parameters, such as displacement and beat rate. The assembly and setup processes for this biaxial bioreactor system are reliable with a success rate greater than 75% for completion of long-term sterile culture. This bioreactor also supports side-by-side assessments of TEVs that are cultured under three types of mechanical conditions (static, uniaxial, and biaxial), all within the same biochemical environment. Using this bioreactor, we examined the impact of biaxial stretching on arterial wall remodeling of TEVs. Biaxial TEVs developed the greatest wall thickness compared with static and uniaxial TEVs. Unlike uniaxial loading, biaxial loading led to undulated collagen fibers that are commonly found in native arteries. More importantly, the biaxial TEVs developed the most mature elastin in the ECM, both qualitatively and quantitatively. The presence of mature extracellular elastin along with the undulated collagen fibers may contribute to the observed vascular compliance in the biaxial TEVs. The current work shows that biaxial stretching is a novel and promising means to improve TEV generation. Furthermore, this novel system allows us to optimize biomechanical conditioning by unraveling the interrelationships among the applied mechanical stress, the resulting ECM properties, and the mechanics of TEVs. PMID:25669988

In vitro fabrication of a tissue engineered human cardiovascular patch for future use in cardiovascular surgery.

PubMed

Yang, Chao; Sodian, Ralf; Fu, Ping; Lüders, Cora; Lemke, Thees; Du, Jing; Hübler, Michael; Weng, Yuguo; Meyer, Rudolf; Hetzer, Roland

2006-01-01

One approach to tissue engineering has been the development of in vitro conditions for the fabrication of functional cardiovascular structures intended for implantation. In this experiment, we developed a pulsatile flow system that provides biochemical and biomechanical signals in order to regulate autologous, human patch-tissue development in vitro. We constructed a biodegradable patch scaffold from porous poly-4-hydroxy-butyrate (P4HB; pore size 80 to 150 microm). The scaffold was seeded with pediatric aortic cells. The cell-seeded patch constructs were placed in a self-developed bioreactor for 7 days to observe potential tissue formation under dynamic cell culture conditions. As a control, cell-seeded scaffolds were not conditioned in the bioreactor system. After maturation in vitro, the analysis of the tissue engineered constructs included biochemical, biomechanical, morphologic, and immunohistochemical examination. Macroscopically, all tissue engineered constructs were covered by cells. After conditioning in the bioreactor, the cells were mostly viable, had grown into the pores, and had formed tissue on the patch construct. Electron microscopy showed confluent smooth surfaces. Additionally, we demonstrated the capacity to generate collagen and elastin under in vitro pulsatile flow conditions in biochemical examination. Biomechanical testing showed mechanical properties of the tissue engineered human patch tissue without any statistical differences in strength or resistance to stretch between the static controls and the conditioned patches. Immunohistochemical examination stained positive for alpha smooth muscle actin, collagen type I, and fibronectin. There was minor tissue formation in the nonconditioned control samples. Porous P4HB may be used to fabricate a biodegradable patch scaffold. Human vascular cells attached themselves to the polymeric scaffold, and extracellular matrix formation was induced under controlled biomechanical and biodynamic stimuli in a self-developed pulsatile bioreactor system.

Energy Efficient Engine Low Pressure Subsystem Flow Analysis

NASA Technical Reports Server (NTRS)

Hall, Edward J.; Lynn, Sean R.; Heidegger, Nathan J.; Delaney, Robert A.

1998-01-01

The objective of this project is to provide the capability to analyze the aerodynamic performance of the complete low pressure subsystem (LPS) of the Energy Efficient Engine (EEE). The analyses were performed using three-dimensional Navier-Stokes numerical models employing advanced clustered processor computing platforms. The analysis evaluates the impact of steady aerodynamic interaction effects between the components of the LPS at design and off-design operating conditions. Mechanical coupling is provided by adjusting the rotational speed of common shaft-mounted components until a power balance is achieved. The Navier-Stokes modeling of the complete low pressure subsystem provides critical knowledge of component aero/mechanical interactions that previously were unknown to the designer until after hardware testing.

Energy Efficient Engine Low Pressure Subsystem Aerodynamic Analysis

NASA Technical Reports Server (NTRS)

Hall, Edward J.; Delaney, Robert A.; Lynn, Sean R.; Veres, Joseph P.

1998-01-01

The objective of this study was to demonstrate the capability to analyze the aerodynamic performance of the complete low pressure subsystem (LPS) of the Energy Efficient Engine (EEE). Detailed analyses were performed using three- dimensional Navier-Stokes numerical models employing advanced clustered processor computing platforms. The analysis evaluates the impact of steady aerodynamic interaction effects between the components of the LPS at design and off- design operating conditions. Mechanical coupling is provided by adjusting the rotational speed of common shaft-mounted components until a power balance is achieved. The Navier-Stokes modeling of the complete low pressure subsystem provides critical knowledge of component acro/mechanical interactions that previously were unknown to the designer until after hardware testing.

Damage Accumulation and Failure of Plasma-Sprayed Thermal Barrier Coatings under Thermal Gradient Cyclic Conditions

NASA Technical Reports Server (NTRS)

Zhu, Dongming; Choi, Sung R.; Ghosn, Louis J.; Miller, rober A.

2005-01-01

Thermal barrier coatings will be more aggressively designed to protect gas turbine engine hot-section components in order to meet future engine higher fuel efficiency and lower emission goals. A fundamental understanding of the sintering and thermal cycling induced delamination of thermal barrier coating systems under engine-like heat flux conditions will potentially help to improve the coating temperature capability. In this study, a test approach is established to emphasize the real-time monitoring and assessment of the coating thermal conductivity, which can initially increase under the steady-state high temperature thermal gradient test due to coating sintering, and later decrease under the thermal gradient cyclic test due to coating cracking and delamination. Thermal conductivity prediction models have been established for a ZrO2-(7- 8wt%)Y2O3 model coating system in terms of heat flux, time, and testing temperatures. The coating delamination accumulation is then assessed based on the observed thermal conductivity response under the combined steady-state and cyclic thermal gradient tests. The coating thermal gradient cycling associated delaminations and failure mechanisms under simulated engine heat-flux conditions will be discussed in conjunction with the coating sintering and fracture testing results.

Thermal barrier coatings for gas-turbine engine applications.

PubMed

Padture, Nitin P; Gell, Maurice; Jordan, Eric H

2002-04-12

Hundreds of different types of coatings are used to protect a variety of structural engineering materials from corrosion, wear, and erosion, and to provide lubrication and thermal insulation. Of all these, thermal barrier coatings (TBCs) have the most complex structure and must operate in the most demanding high-temperature environment of aircraft and industrial gas-turbine engines. TBCs, which comprise metal and ceramic multilayers, insulate turbine and combustor engine components from the hot gas stream, and improve the durability and energy efficiency of these engines. Improvements in TBCs will require a better understanding of the complex changes in their structure and properties that occur under operating conditions that lead to their failure. The structure, properties, and failure mechanisms of TBCs are herein reviewed, together with a discussion of current limitations and future opportunities.

40 CFR 141.100 - Criteria and procedures for public water systems using point-of-entry devices.

Code of Federal Regulations, 2011 CFR

2011-07-01

... include physical measurements and observations such as total flow treated and mechanical condition of the... engineering design review of the point-of-entry devices. (2) The design and application of the point-of-entry...

40 CFR 141.100 - Criteria and procedures for public water systems using point-of-entry devices.

Code of Federal Regulations, 2013 CFR

2013-07-01

... include physical measurements and observations such as total flow treated and mechanical condition of the... engineering design review of the point-of-entry devices. (2) The design and application of the point-of-entry...

40 CFR 141.100 - Criteria and procedures for public water systems using point-of-entry devices.

Code of Federal Regulations, 2012 CFR

2012-07-01

... include physical measurements and observations such as total flow treated and mechanical condition of the... engineering design review of the point-of-entry devices. (2) The design and application of the point-of-entry...

40 CFR 65.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... means a system or combination of systems and portable containers to capture purged liquids. Containers... data acquisition and availability requirements of this part used to sample, condition (if applicable... (available from the American Society of Mechanical Engineers, PO Box 2900, Fairfield, NJ 07007-2900). High...

Chemical kinetics of octane sensitivity in a spark-ignition engine (Chemical Kinetics of Octane Sensitivity in a Spark Ignition Engine)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Westbrook, Charles K.; Mehl, Marco; Pitz, William J.

This article uses a chemical kinetic modeling approach to study the influences of fuel molecular structure on Octane Sensitivity (OS) in Spark Ignition (SI) engines. Octane Sensitivity has the potential to identify fuels that can be used in next-generation high compression, turbocharged SI engines to avoid unwanted knocking conditions and extend the range of operating conditions that can be used in such engines. While the concept of octane numbers of different fuels has been familiar for many years, the variations of their values and their role in determining Octane Sensitivity have not been addressed previously in terms of the basicmore » structures of the fuel molecules. In particular, the importance of electron delocalization on low temperature hydrocarbon reactivity and its role in determining OS in engine fuel is described here for the first time. Finally, the role of electron delocalization on fuel reactivity and Octane Sensitivity is illustrated for a very wide range of engine fuel types, including n-alkane, 1-olefin, n-alcohol, and n-alkyl benzenes, and the unifying features of these fuels and their common trends, using existing detailed chemical kinetic reaction mechanisms that have been collected and unified to produce an overall model with unprecedented capabilities.« less

Chemical kinetics of octane sensitivity in a spark-ignition engine (Chemical Kinetics of Octane Sensitivity in a Spark Ignition Engine)

DOE PAGES

Westbrook, Charles K.; Mehl, Marco; Pitz, William J.; ...

2016-07-11

This article uses a chemical kinetic modeling approach to study the influences of fuel molecular structure on Octane Sensitivity (OS) in Spark Ignition (SI) engines. Octane Sensitivity has the potential to identify fuels that can be used in next-generation high compression, turbocharged SI engines to avoid unwanted knocking conditions and extend the range of operating conditions that can be used in such engines. While the concept of octane numbers of different fuels has been familiar for many years, the variations of their values and their role in determining Octane Sensitivity have not been addressed previously in terms of the basicmore » structures of the fuel molecules. In particular, the importance of electron delocalization on low temperature hydrocarbon reactivity and its role in determining OS in engine fuel is described here for the first time. Finally, the role of electron delocalization on fuel reactivity and Octane Sensitivity is illustrated for a very wide range of engine fuel types, including n-alkane, 1-olefin, n-alcohol, and n-alkyl benzenes, and the unifying features of these fuels and their common trends, using existing detailed chemical kinetic reaction mechanisms that have been collected and unified to produce an overall model with unprecedented capabilities.« less

Genetic engineering of woody plants: current and future targets in a stressful environment.

PubMed

Osakabe, Yuriko; Kajita, Shinya; Osakabe, Keishi

2011-06-01

Abiotic stress is a major factor in limiting plant growth and productivity. Environmental degradation, such as drought and salinity stresses, will become more severe and widespread in the world. To overcome severe environmental stress, plant biotechnologies, such as genetic engineering in woody plants, need to be implemented. The adaptation of plants to environmental stress is controlled by cascades of molecular networks including cross-talk with other stress signaling mechanisms. The present review focuses on recent studies concerning genetic engineering in woody plants for the improvement of the abiotic stress responses. Furthermore, it highlights the recent advances in the understanding of molecular responses to stress. The review also summarizes the basis of a molecular mechanism for cell wall biosynthesis and the plant hormone responses to regulate tree growth and biomass in woody plants. This would facilitate better understanding of the control programs of biomass production under stressful conditions. Copyright © Physiologia Plantarum 2011.

Illite Dissolution Rates and Equation (100 to 280 dec C)

DOE Data Explorer

Carroll, Susan

2014-10-17

The objective of this suite of experiments was to develop a useful kinetic dissolution expression for illite applicable over an expanded range of solution pH and temperature conditions representative of subsurface conditions in natural and/or engineered geothermal reservoirs. Using our new data, the resulting rate equation is dependent on both pH and temperature and utilizes two specific dissolution mechanisms (a “neutral” and a “basic” mechanism). The form of this rate equation should be easily incorporated into most existing reactive transport codes for to predict rock-water interactions in EGS shear zones.

Intelligent Life-Extending Controls for Aircraft Engines

NASA Technical Reports Server (NTRS)

Guo, Ten-Huei; Chen, Philip; Jaw, Link

2005-01-01

Aircraft engine controllers are designed and operated to provide desired performance and stability margins. The purpose of life-extending-control (LEC) is to study the relationship between control action and engine component life usage, and to design an intelligent control algorithm to provide proper trade-offs between performance and engine life usage. The benefit of this approach is that it is expected to maintain safety while minimizing the overall operating costs. With the advances of computer technology, engine operation models, and damage physics, it is necessary to reevaluate the control strategy fro overall operating cost consideration. This paper uses the thermo-mechanical fatigue (TMF) of a critical component to demonstrate how an intelligent engine control algorithm can drastically reduce the engine life usage with minimum sacrifice in performance. A Monte Carlo simulation is also performed to evaluate the likely engine damage accumulation under various operating conditions. The simulation results show that an optimized acceleration schedule can provide a significant life saving in selected engine components.

Study on the performance of the articulated mechanism of tracked all-terrain vehicle

NASA Astrophysics Data System (ADS)

Meng, Zhongliang; Zang, Hao

2018-04-01

Tracked all-terrain vehicle consists of two vehicle bodies featured by superior performance, the running system which can meet the all-terrain requirement, the unique steering system, power system and the vehicle body protection system. This paper focuses on the study of the five freely articulated steering system of crawler-type all-terrain engineering vehicle. The study on the dynamic characteristics of the articulated steering system can't do without the dynamic analysis of the whole vehicle. Therefore, it first studies the overall model of the tracked all-terrain vehicle, and then based on the critical states where the overall model is situated under different road conditions, mathematical models of the articulated mechanism are built under different operating conditions and also the load bearing condition of the articulated mechanism is deduced.

Evaluation of Separation Mechanism Design for the Orion/Ares Launch Vehicle

NASA Technical Reports Server (NTRS)

Konno, Kevin E.; Catalano, Daniel A.; Krivanek, Thomas M.

2008-01-01

As a part of the preliminary design work being performed for the Orion vehicle, the Orion to Spacecraft Adaptor (SA) separation mechanism was analyzed and sized, with findings presented here. Sizing is based on worst case abort condition as a result of an anomaly driving the launch vehicle engine thrust vector control hard-over causing a severe vehicle pitch over. This worst case scenario occurs just before Upper Stage Main Engine Cut-Off (MECO) when the vehicle is the lightest and the damping effect due to propellant slosh has been reduced to a minimum. To address this scenario and others, two modeling approaches were invoked. The first approach was a detailed 2-D (Simulink) model to quickly assess the Service Module Engine nozzle to SA clearance for a given separation mechanism. The second approach involved the generation of an Automatic Dynamic Analysis of Mechanical Systems (ADAMS) model to assess secondary effects due to mass centers of gravity that were slightly off the vehicle centerline. It also captured any interference between the Solar Arrays and the Spacecraft Adapter. A comparison of modeling results and accuracy are discussed. Most notably, incorporating a larger SA flange diameter allowed for a natural separation of the Orion and its engine nozzle even at relatively large pitch rates minimizing the kickoff force. Advantages and disadvantages of the 2-D model vs. a full 3-D (ADAMS) model are discussed as well.

Evaluation of Separation Mechanism Design for the Orion/Ares Launch Vehicle

NASA Technical Reports Server (NTRS)

Konno, Kevin E.; Catalano, Daniel A.; Krivanek, Thomas M.

2008-01-01

As a part of the preliminary design work being performed for the Orion vehicle, the Orion to Spacecraft Adaptor (SA) separation mechanism was analyzed and sized, with findings presented here. Sizing is based on worst case abort condition as a result of an anomaly driving the launch vehicle engine thrust vector control hard-over causing a severe vehicle pitch over. This worst-case scenario occurs just before Upper Stage Main Engine Cut-Off when the vehicle is the lightest and the damping effect due to propellant slosh has been reduced to a minimum. To address this scenario and others, two modeling approaches were invoked. The first approach was a detailed Simulink model to quickly assess the Service Module Engine nozzle to SA clearance for a given separation mechanism. The second approach involved the generation of an Automatic Dynamic Analysis of Mechanical Systems (ADAMS) model to assess secondary effects due to mass centers of gravity that were slightly off the vehicle centerline. It also captured any interference between the Solar Arrays and the Spacecraft Adapter. A comparison of modeling results and accuracy are discussed. Most notably, incorporating a larger SA flange diameter allowed for a natural separation of the Orion and its engine nozzle even at relatively large pitch rates minimizing the kickoff force. Advantages and disadvantages of the Simulink model vs. a full geometric ADAMS model are discussed as well.

Evaluation of Separation Mechanism Design for the Orion/Ares Launch Vehicle

NASA Technical Reports Server (NTRS)

Konno, Kevin E.; Catalano, Daniel A.; Krivanek, Thomas M.

2008-01-01

As a part of the preliminary design work being performed for the Orion vehicle, the Orion to Spacecraft Adaptor (SA) separation mechanism was analyzed and sized, with findings presented here. Sizing is based on worst case abort condition as a result of an anomaly driving the launch vehicle engine thrust vector control hard-over causing a severe vehicle pitch over. This worst case scenario occurs just before Upper Stage Main Engine Cut-Off (MECO) when the vehicle is the lightest and the damping effect due to propellant slosh has been reduced to a minimum. To address this scenario and others, two modeling approaches were invoked. The first approach was a detailed Simulink model to quickly assess the Service Module Engine nozzle to SA clearance for a given separation mechanism. The second approach involved the generation of an Automatic Dynamic Analysis of Mechanical Systems (ADAMS) model to assess secondary effects due to mass centers of gravity that were slightly off the vehicle centerline. It also captured any interference between the Solar Arrays and the Spacecraft Adapter. A comparison of modeling results and accuracy are discussed. Most notably, incorporating a larger SA flange diameter allowed for a natural separation of the Orion and it's engine nozzle even at relatively large pitch rates minimizing the kickoff force. Advantages and disadvantages of the Simulink model vs. a full geometric ADAMS model are discussed as well.

Electrospinning of gelatin and SMPU with carbon nanotubes for tissue engineering scaffolds.

PubMed

Mejia, Monica A; Hoyos, Lina M; Zapata, Jenniffer; Restrepo, Luz M; Moneada, Maria E

2016-08-01

The nanofibres created by electrospinning technique are currently used for a variety of applications in tissue engineering; and Gelatin and Polyurethane Shape-Memory (SMPU) have important results in biomedicine. Similarly, carbon nanotubes combined with other biomaterials change important properties, opening new opportunities for biomedical applications. In this work, we constructed scaffold using electrospinning technique based in bovine-hide gelatin, SMPU and both materials hybrid with carbon nanotube. Morphology and cytotoxicity were evaluated and mechanical properties for two materials were obtained in scaffold building. Morphological, mechanical and citotoxic properties of the electrospun fibers were found to be dependent of alteration in materials concentration, electrospinning conditions and MWCNT concentration. According to morphological, cytotoxic and mechanical analysis, SMPU more MWCNT were the best material, with nanofibers of 451 nm, tensile strength of 1.912 MPa, and a high ratio surface volume.

Impacts of genetically engineered alterations in carbon sink pathways on photosynthetic performance

DOE PAGES

Holland, Steven C.; Artier, Juliana; Miller, Neil T.; ...

2016-10-05

Genetic engineering of photosynthetic organisms typically redirects native metabolism towards desirable products, which thereby represent new metabolic sinks. There is limited information on how these modifications impact the evolved mechanisms of photosynthetic energy metabolism and cellular growth. Two engineered strains of Synechocystis sp. PCC 6803 with altered carbon sink capacity were assayed for their photosynthetic and CO 2 concentrating mechanism properties in conditions of high and low inorganic carbon (Ci) availability. In the ΔglgC mutant, glycogen cannot be synthesized and a carbon sink pathway has been effectively removed. The JU547 strain has been engineered by integration of the Pseudomonas syringaemore » ethylene forming enzyme and provides a new sink. When cultured under high carbon conditions, ΔglgC displayed diminished photochemical efficiency, a more reduced NADPH pool, delayed initiation of the Calvin-Benson-Bassham cycle, and impairment of linear and cyclic electron flows. It also exhibited a large decrease in photochemical quenching indicative of the accumulation of Q A-, normally associated with a reduced PQ pool, but appears instead to be the result of an undefined dissipative mechanism to spill excess energy. In the case of carbon sink integration, JU547 displayed slightly more oxidized PQ and NADPH pools and increased rates of cyclic electron flow and an enhanced demand for inorganic carbon as suggested by increase in the expression of the bicarbonate transporter, SbtA. Overall, the results highlight the importance of the native regulatory network of autotrophic metabolism in governing photosynthetic performance and provide cogent examples of both predicable and difficult to predict phenotypic consequences upon installation of new pathways in autotrophs.« less

Can increased leaf photosynthesis be converted into higher crop mass production? A simulation study for rice using the crop model GECROS

PubMed Central

Struik, Paul C.

2017-01-01

Abstract Various genetic engineering routes to enhance C3 leaf photosynthesis have been proposed to improve crop productivity. However, their potential contribution to crop productivity needs to be assessed under realistic field conditions. Using 31 year weather data, we ran the crop model GECROS for rice in tropical, subtropical, and temperate environments, to evaluate the following routes: (1) improving mesophyll conductance (gm); (2) improving Rubisco specificity (Sc/o); (3) improving both gm and Sc/o; (4) introducing C4 biochemistry; (5) introducing C4 Kranz anatomy that effectively minimizes CO2 leakage; (6) engineering the complete C4 mechanism; (7) engineering cyanobacterial bicarbonate transporters; (8) engineering a more elaborate cyanobacterial CO2-concentrating mechanism (CCM) with the carboxysome in the chloroplast; and (9) a mechanism that combines the low ATP cost of the cyanobacterial CCM and the high photosynthetic capacity per unit leaf nitrogen. All routes improved crop mass production, but benefits from Routes 1, 2, and 7 were ≤10%. Benefits were higher in the presence than in the absence of drought, and under the present climate than for the climate predicted for 2050. Simulated crop mass differences resulted not only from the increased canopy photosynthesis competence but also from changes in traits such as light interception and crop senescence. The route combinations gave larger effects than the sum of the effects of the single routes, but only Route 9 could bring an advantage of ≥50% under any environmental conditions. To supercharge crop productivity, exploring a combination of routes in improving the CCM, photosynthetic capacity, and quantum efficiency is required. PMID:28379522

Structural Evaluation of a Space Shuttle Main Engine (SSME) High Pressure Fuel Turbopump Turbine Blade

NASA Technical Reports Server (NTRS)

Abdul-Aziz, Ali

1996-01-01

Thermal and structural finite-element analyses were performed on the first high pressure fuel turbopump turbine blade of the space shuttle main engine (SSME). A two-dimensional (2-D) finite-element model of the blade and firtree disk attachment was analyzed using the general purpose MARC (finite-element) code. The loading history applied is a typical test stand engine cycle mission, which consists of a startup condition with two thermal spikes, a steady state and a shutdown transient. The blade material is a directionally solidified (DS) Mar-M 246 alloy, the blade rotor is forged with waspalloy material. Thermal responses under steady-state and transient conditions were calculated. The stresses and strains under the influence of mechanical and thermal loadings were also determined. The critical regions that exhibited high stresses and severe localized plastic deformation were the blade-rotor gaps.

Microgravity cultivation of cells and tissues

NASA Technical Reports Server (NTRS)

Freed, L. E.; Pellis, N.; Searby, N.; de Luis, J.; Preda, C.; Bordonaro, J.; Vunjak-Novakovic, G.

1999-01-01

In vitro studies of cells and tissues in microgravity, either simulated by cultivation conditions on earth or actual, during spaceflight, are expected to help identify mechanisms underlying gravity sensing and transduction in biological organisms. In this paper, we review rotating bioreactor studies of engineered skeletal and cardiovascular tissues carried out in unit gravity, a four month long cartilage tissue engineering study carried out aboard the Mir Space Station, and the ongoing laboratory development and testing of a system for cell and tissue cultivation aboard the International Space Station.

Materials by Design - Computational Alloy Design for Corrosion

DTIC Science & Technology

2011-02-01

Es = + 0.33 eV Cs Rb K · ~·Ba Sr ::~ \\ H ~ YCd ./ G B FS A~ Zn " Be• ’f_ Ni?.Au SeA. ’\\ . At-v Rh Ru • Zr Ja Mo Tc _,. • • • pt • lr Nb w...Windows Air Conditioning Autoflight Electrical Power Navigation Engine Exhaust Stabilizer Doors Fuel system Nacelles/Pylons Power Plant Equip...p. 14 ASETSDefense 2011: Sustainable Surface Engineering for Aerospace and Defense Workshop Quantum Mechanics Insights into SCC resistance 3.5 -E 0

Lunar soil properties and soil mechanics

NASA Technical Reports Server (NTRS)

Mitchell, J. K.; Houston, W. N.

1974-01-01

The long-range objectives were to develop methods of experimentation and analysis for the determination of the physical properties and engineering behavior of lunar surface materials under in situ environmental conditions. Data for this purpose were obtained from on-site manned investigations, orbiting and softlanded spacecraft, and terrestrial simulation studies. Knowledge of lunar surface material properties are reported for the development of models for several types of lunar studies and for the investigation of lunar processes. The results have direct engineering application for manned missions to the moon.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rittman, Dylan R.; Turner, Katlyn M.; Park, Sulgiye

Strain engineering is a promising method for next-generation materials processing techniques. Here, we use mechanical milling and annealing followed by compression in diamond anvil cell to tailor the intrinsic and extrinsic strain in pyrochlore, Dy 2Ti 2O 7 and Dy 2Zr 2O 7. Raman spectroscopy, X-ray pair distribution function analysis, and X-ray diffraction were used to characterize atomic order over short-, medium-, and long-range spatial scales, respectively, under ambient conditions. Raman spectroscopy and X-ray diffraction were further employed to interrogate the material in situ at high pressure. High-pressure behavior is found to depend on the species and concentration of defectsmore » in the sample at ambient conditions. Overall, we show that defects can be engineered to lower the phase transformation onset pressure by ~50% in the ordered pyrochlore Dy 2Ti 2O 7, and lower the phase transformation completion pressure by ~20% in the disordered pyrochlore Dy 2Zr 2O 7. Lastly, these improvements are achieved without significantly sacrificing mechanical integrity, as characterized by bulk modulus.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rittman, Dylan R.; Turner, Katlyn M.; Park, Sulgiye

Strain engineering is a promising method for next-generation materials processing techniques. Here, we use mechanical milling and annealing followed by compression in diamond anvil cell to tailor the intrinsic and extrinsic strain in pyrochlore, Dy 2Ti 2O 7 and Dy 2Zr 2O 7. Raman spectroscopy, X-ray pair distribution function analysis, and X-ray diffraction were used to characterize atomic order over short-, medium-, and long-range spatial scales, respectively, under ambient conditions. Raman spectroscopy and X-ray diffraction were further employed to interrogate the material in situ at high pressure. High-pressure behavior is found to depend on the species and concentration of defectsmore » in the sample at ambient conditions. Overall, we show that defects can be engineered to lower the phase transformation onset pressure by ~50% in the ordered pyrochlore Dy 2Zr 2O 7, and lower the phase transformation completion pressure by ~20% in the disordered pyrochlore Dy 2Zr 2O 7. These improvements are achieved without significantly sacrificing mechanical integrity, as characterized by bulk modulus.« less

Physics and chemistry of plasma-assisted combustion.

PubMed

Starikovskiy, Andrey

2015-08-13

There are several mechanisms that affect a gas when using discharge plasma to initiate combustion or to stabilize a flame. There are two thermal mechanisms-the homogeneous and inhomogeneous heating of the gas due to 'hot' atom thermalization and vibrational and electronic energy relaxation. The homogeneous heating causes the acceleration of the chemical reactions. The inhomogeneous heating generates flow perturbations, which promote increased turbulence and mixing. Non-thermal mechanisms include the ionic wind effect (the momentum transfer from an electric field to the gas due to the space charge), ion and electron drift (which can lead to additional fluxes of active radicals in the gradient flows in the electric field) and the excitation, dissociation and ionization of the gas by e-impact, which leads to non-equilibrium radical production and changes the kinetic mechanisms of ignition and combustion. These mechanisms, either together or separately, can provide additional combustion control which is necessary for ultra-lean flames, high-speed flows, cold low-pressure conditions of high-altitude gas turbine engine relight, detonation initiation in pulsed detonation engines and distributed ignition control in homogeneous charge-compression ignition engines, among others. Despite the lack of knowledge in mechanism details, non-equilibrium plasma demonstrates great potential for controlling ultra-lean, ultra-fast, low-temperature flames and is extremely promising technology for a very wide range of applications. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

Co-Optima Project E2.2.2: Accelerate Development of ACI/LTC Fuel Effects on RCCI Combustion.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Musculus, Mark P.

Many advanced combustion approaches have demonstrated potential for achieving diesel-like thermal efficiency but with much lower pollutant emissions of particulate matter (PM) and nitrogen oxides (NOx). RCCI is one advanced combustion concept, which makes use of in-cylinder blending of two fuels with differing reactivity for improved control of the combustion phasing and rate (Reitz et al., 2015). Previous research and development at ORNL has demonstrated successful implementation of RCCI on a light-duty multi-cylinder engine over a wide range of operating conditions (Curran et al., 2015). Several challenges were encountered when extending the research to practical applications, including limits to themore » operating range, both for high and low loads. Co-optimizing the engine and fuel aspects of the RCCI approach might allow these operating limits to be overcome. The in-cylinder mechanisms by which fuel properties interact with engine operating condition variables is not well understood, however, in part because RCCI is a new combustion concept that is still being developed, and limited data have been acquired to date, especially using in-cylinder optical/imaging diagnostics. The objective of this work is to use in-cylinder diagnostics in a heavy-duty single-cylinder optical engine at SNL to understand the interplay between fuel properties and engine hardware and operating conditions for RCCI in general, and in particular for the light-duty multi-cylinder all-metal RCCI engine experiments at ORNL.« less

A High Throughput Model of Post-Traumatic Osteoarthritis using Engineered Cartilage Tissue Analogs

PubMed Central

Mohanraj, Bhavana; Meloni, Gregory R.; Mauck, Robert L.; Dodge, George R.

2014-01-01

(1) Objective A number of in vitro models of post-traumatic osteoarthritis (PTOA) have been developed to study the effect of mechanical overload on the processes that regulate cartilage degeneration. While such frameworks are critical for the identification therapeutic targets, existing technologies are limited in their throughput capacity. Here, we validate a test platform for high-throughput mechanical injury incorporating engineered cartilage. (2) Method We utilized a high throughput mechanical testing platform to apply injurious compression to engineered cartilage and determined their strain and strain rate dependent responses to injury. Next, we validated this response by applying the same injury conditions to cartilage explants. Finally, we conducted a pilot screen of putative PTOA therapeutic compounds. (3) Results Engineered cartilage response to injury was strain dependent, with a 2-fold increase in GAG loss at 75% compared to 50% strain. Extensive cell death was observed adjacent to fissures, with membrane rupture corroborated by marked increases in LDH release. Testing of established PTOA therapeutics showed that pan-caspase inhibitor (ZVF) was effective at reducing cell death, while the amphiphilic polymer (P188) and the free-radical scavenger (NAC) reduced GAG loss as compared to injury alone. (4) Conclusions The injury response in this engineered cartilage model replicated key features of the response from cartilage explants, validating this system for application of physiologically relevant injurious compression. This study establishes a novel tool for the discovery of mechanisms governing cartilage injury, as well as a screening platform for the identification of new molecules for the treatment of PTOA. PMID:24999113

Modeling of a resonant heat engine

NASA Astrophysics Data System (ADS)

Preetham, B. S.; Anderson, M.; Richards, C.

2012-12-01

A resonant heat engine in which the piston assembly is replaced by a sealed elastic cavity is modeled and analyzed. A nondimensional lumped-parameter model is derived and used to investigate the factors that control the performance of the engine. The thermal efficiency predicted by the model agrees with that predicted from the relation for the Otto cycle based on compression ratio. The predictions show that for a fixed mechanical load, increasing the heat input results in increased efficiency. The output power and power density are shown to depend on the loading for a given heat input. The loading condition for maximum output power is different from that required for maximum power density.

Testing of Composite Fan Vanes With Erosion-Resistant Coating Accelerated

NASA Technical Reports Server (NTRS)

Bowman, Cheryl L.; Sutter, James K.; Otten, Kim D.; Samorezov, Sergey; Perusek, Gail P.

2004-01-01

The high-cycle fatigue of composite stator vanes provided an accelerated life-state prior to insertion in a test stand engine. The accelerated testing was performed in the Structural Dynamics Laboratory at the NASA Glenn Research Center under the guidance of Structural Mechanics and Dynamics Branch personnel. Previous research on fixturing and test procedures developed at Glenn determined that engine vibratory conditions could be simulated for polymer matrix composite vanes by using the excitation of a combined slip table and electrodynamic shaker in Glenn's Structural Dynamics Laboratory. Bench-top testing gave researchers the confidence to test the coated vanes in a full-scale engine test.

Loading Deformation Characteristic Simulation Study of Engineering Vehicle Refurbished Tire

NASA Astrophysics Data System (ADS)

Qiang, Wang; Xiaojie, Qi; Zhao, Yang; Yunlong, Wang; Guotian, Wang; Degang, Lv

2018-05-01

The paper constructed engineering vehicle refurbished tire computer geometry model, mechanics model, contact model, finite element analysis model, did simulation study on load-deformation property of engineering vehicle refurbished tire by comparing with that of the new and the same type tire, got load-deformation of engineering vehicle refurbished tire under the working condition of static state and ground contact. The analysis result shows that change rules of radial-direction deformation and side-direction deformation of engineering vehicle refurbished tire are close to that of the new tire, radial-direction and side-direction deformation value is a little less than that of the new tire. When air inflation pressure was certain, radial-direction deformation linear rule of engineer vehicle refurbished tire would increase with load adding, however, side-direction deformation showed linear change rule, when air inflation pressure was low; and it would show increase of non-linear change rule, when air inflation pressure was very high.

Design of a miniature hydrogen fueled gas turbine engine

NASA Technical Reports Server (NTRS)

Burnett, M.; Lopiccolo, R. C.; Simonson, M. R.; Serovy, G. K.; Okiishi, T. H.; Miller, M. J.; Sisto, F.

1973-01-01

The design, development, and delivery of a miniature hydrogen-fueled gas turbine engine are discussed. The engine was to be sized to approximate a scaled-down lift engine such as the teledyne CAE model 376. As a result, the engine design emerged as a 445N(100 lb.)-thrust engine flowing 0.86 kg (1.9 lbs.) air/sec. A 4-stage compressor was designed at a 4.0 to 1 pressure ratio for the above conditions. The compressor tip diameter was 9.14 cm (3.60 in.). To improve overall engine performance, another compressor with a 4.75 to 1 pressure ratio at the same tip diameter was designed. A matching turbine for each compressor was also designed. The turbine tip diameter was 10.16 cm (4.0 in.). A combustion chamber was designed, built, and tested for this engine. A preliminary design of the mechanical rotating parts also was completed and is discussed. Three exhaust nozzle designs are presented.

Micrometer scale guidance of mesenchymal stem cells to form structurally oriented large-scale tissue engineered cartilage.

PubMed

Chou, Chih-Ling; Rivera, Alexander L; Williams, Valencia; Welter, Jean F; Mansour, Joseph M; Drazba, Judith A; Sakai, Takao; Baskaran, Harihara

2017-09-15

Current clinical methods to treat articular cartilage lesions provide temporary relief of the symptoms but fail to permanently restore the damaged tissue. Tissue engineering, using mesenchymal stem cells (MSCs) combined with scaffolds and bioactive factors, is viewed as a promising method for repairing cartilage injuries. However, current tissue engineered constructs display inferior mechanical properties compared to native articular cartilage, which could be attributed to the lack of structural organization of the extracellular matrix (ECM) of these engineered constructs in comparison to the highly oriented structure of articular cartilage ECM. We previously showed that we can guide MSCs undergoing chondrogenesis to align using microscale guidance channels on the surface of a two-dimensional (2-D) collagen scaffold, which resulted in the deposition of aligned ECM within the channels and enhanced mechanical properties of the constructs. In this study, we developed a technique to roll 2-D collagen scaffolds containing MSCs within guidance channels in order to produce a large-scale, three-dimensional (3-D) tissue engineered cartilage constructs with enhanced mechanical properties compared to current constructs. After rolling the MSC-scaffold constructs into a 3-D cylindrical structure, the constructs were cultured for 21days under chondrogenic culture conditions. The microstructure architecture and mechanical properties of the constructs were evaluated using imaging and compressive testing. Histology and immunohistochemistry of the constructs showed extensive glycosaminoglycan (GAG) and collagen type II deposition. Second harmonic generation imaging and Picrosirius red staining indicated alignment of neo-collagen fibers within the guidance channels of the constructs. Mechanical testing indicated that constructs containing the guidance channels displayed enhanced compressive properties compared to control constructs without these channels. In conclusion, using a novel roll-up method, we have developed large scale MSC based tissue-engineered cartilage that shows microscale structural organization and enhanced compressive properties compared to current tissue engineered constructs. Tissue engineered cartilage constructs made with human mesenchymal stem cells (hMSCs), scaffolds and bioactive factors are a promising solution to treat cartilage defects. A major disadvantage of these constructs is their inferior mechanical properties compared to the native tissue, which is likely due to the lack of structural organization of the extracellular matrix of the engineered constructs. In this study, we developed three-dimensional (3-D) cartilage constructs from rectangular scaffold sheets containing hMSCs in micro-guidance channels and characterized their mechanical properties and metabolic requirements. The work led to a novel roll-up method to embed 2-D microscale structures in 3-D constructs. Further, micro-guidance channels incorporated within the 3-D cartilage constructs led to the production of aligned cell-produced matrix and enhanced mechanical function. Copyright © 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

CF60 Concrete Composition Design and Application on Fudiankou Xijiang Super Large Bridge

NASA Astrophysics Data System (ADS)

Qiu, Yi Mei; Wen, Sen Yuan; Chen, Jun Xiang

2018-06-01

Guangxi Wuzhou City Ring Road Fudiankou Xijiang super large bridge CF60 concrete is a new multi-phase composite high-performance concrete, this paper for the Fudiankou Xijiang bridge structure and characteristics of the project, in accordance with the principle of local materials and technical specification requirements, combined with the site conditions of CF60 engineering high performance concrete component materials, proportion and the technical performance, quantify the main physical and mechanical performance index. Analysis main influencing factors of the technical indicators, reasonable adjustment of concrete mix design parameters, and the use of technical means of admixture and multi-function composite admixture of concrete, obtain the optimal proportion of good work, process, mechanical properties stability and durability of engineering properties, recommend and verification of concrete mix; to explore the CF60 high performance concrete Soil in the Fudiankou Xijiang bridge application technology, detection and tracking the quality of concrete construction, concrete structure during the construction of the key technology and control points is proposed, evaluation of CF60 high performance concrete in the actual engineering application effect and benefit to ensure engineering quality of bridge structure and service life, and super long span bridge engineering construction to provide basis and reference.

Recruitment and Retention of Indians in Science and Engineering (RISE)

NASA Technical Reports Server (NTRS)

Karnawat, Sunil

1997-01-01

Fifteen students from Turtle Mountain Community College were selected to participate in activities of the RISE project last summer. Eight students successfully completed project activities and received stipends for their participation. These eight students are (1) Jamie Gable, (2) John Morin, (3) Patrick Belgarde, (4) Jason Laducer, (5) Alex Johnson, (6) Eric Houle, (7) Gary Renault, and (8) Kenny DeCoteau. In the fall of 1998, Jamie Gable and Gary Renault went to North Dakota State University to pursue their undergraduate degrees in mechanical engineering, and John Morin and Alex Johnson joined the University of North Dakota's electrical engineering and industrial technology programs, respectively. Remaining four students will continue to participate in the RISE activities this year and transfer to the universities next year. Seven students who failed to complete the RISE project activities during the current award period are encouraged to participate again this fall. The RISE students were enrolled in a special course called "Introduction to Engineering Materials." The project director, Dr. Kamawat, taught the course on Saturdays and Sundays. Theoretical and mathematical background on engineering materials and careers in various engineering professions were discussed in this course. The students attended guest lectures given by engineers and professors and visited local industries. In addition, the students went to North Dakota State University (NDSU) at Fargo, ND, and the University of Minnesota (UMN) at Minneapolis, MN, to tour their engineering departments. At NDSU, they conducted laboratory tests on various engineering materials, such as concrete, steel, wood, plastics, and carbon composites. The students investigated the mechanical behavior of these materials under various loading conditions, collected data, interpreted data, identified possible errors, determined the mechanical properties, and wrote reports on their findings. The students created posters describing their results on the behavior of engineering material. The posters were displayed in the TMCC's student lounge.

Engineering and Design: Geotechnical Analysis by the Finite Element Method

DTIC Science & Technology

1995-07-31

of an Idealized ’Wet Clay’.” Nobari, E. S., Lee, K. L., and Duncan, J. M. Soil Mechanics, Wiesbaden I, 47-54. (1973). “ Hydraulic Fracturing in Zoned...nonsteady flow conditions - Pore pressures induced by loading under undrained conditions - Potential for cracking in embankment dams - Potential for hydraulic ... fracturing in embankment dams - Potential for hydraulic separation between concrete and soil - Settlements and horizontal movements b. Comparing

46 CFR 113.35-15 - Mechanical engine order telegraph systems; application.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Mechanical engine order telegraph systems; application...) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-15 Mechanical engine order telegraph systems; application. If a mechanical engine order telegraph...

46 CFR 113.35-15 - Mechanical engine order telegraph systems; application.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Mechanical engine order telegraph systems; application...) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-15 Mechanical engine order telegraph systems; application. If a mechanical engine order telegraph...

46 CFR 113.35-15 - Mechanical engine order telegraph systems; application.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Mechanical engine order telegraph systems; application...) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-15 Mechanical engine order telegraph systems; application. If a mechanical engine order telegraph...

46 CFR 113.35-15 - Mechanical engine order telegraph systems; application.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Mechanical engine order telegraph systems; application...) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-15 Mechanical engine order telegraph systems; application. If a mechanical engine order telegraph...

Damage in fatigue: A new outlook

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, K.J.

1995-12-01

This paper concentrates on the difficulties produced by linear elastic fracture mechanics (LEFM) and how recent research has removed many of these difficulties thereby permitting the design engineer to have a much improved basis for solving complex problems of engineering plant subjected to cyclic loading. This paper intends to show that: (1) In polycrystalline materials the period of initiation is in reality, zero and fatigue lifetime is entirely composed of crack propagation. (2) The fatigue limit of a metal, component or structure is related to whether or not a crack can propagate. (3) Elastic Fracture Mechanics is only a beginningmore » in the science of, and application of, fracture mechanics. (4) Fatigue Damage is current crack length and the rate of damage accumulation is the rate of crack growth. (5) Only two basic forms of crack extension occur when any combination of the three loading mode mechanisms (Modes 1, 2, and 3) are applied, namely Stage 1 (shear crack growth) and Stage 2 (tensile crack growth). (6) Three fundamentally different fatigue crack growth thresholds exist. (7) The fatigue resistance of a metal is predominantly concerned with a crack changing its crack-growth direction, ie from Stage 1 to Stage 2, or vice versa. (8) Notches fall into two clearly defined categories; sharp notches where failure is related to the mechanical threshold condition, and shallow notches where failure is related to the material threshold condition. (9) Complex three-dimensional cyclic stress systems should be evaluated with respect to the possible Stage 1 and Stage 2 crack growth planes. (10) Barriers to fatigue crack growth can have origins in the microstructure (eg: grain boundaries) and in the mechanical state (eg: other crack systems). (11) The removal of a fatigue limit by a corrosive environment can be evaluated by the interface conditions between the Elastic-Plastic Fracture Mechanics (EPFM) and Microstructural Fracture Mechanics (MFM) regimes.« less

Dynamic culture induces a cell type-dependent response impacting on the thickness of engineered connective tissues.

PubMed

Fortier, Guillaume Marceau; Gauvin, Robert; Proulx, Maryse; Vallée, Maud; Fradette, Julie

2013-04-01

Mesenchymal cells are central to connective tissue homeostasis and are widely used for tissue-engineering applications. Dermal fibroblasts and adipose-derived stromal cells (ASCs) allow successful tissue reconstruction by the self-assembly approach of tissue engineering. This method leads to the production of multilayered tissues, devoid of exogenous biomaterials, that can be used as stromal compartments for skin or vesical reconstruction. These tissues are formed by combining cell sheets, generated through cell stimulation with ascorbic acid, which favours the cell-derived production/organization of matrix components. Since media motion can impact on cell behaviour, we investigated the effect of dynamic culture on mesenchymal cells during tissue reconstruction, using the self-assembly method. Tissues produced using ASCs in the presence of a wave-like movement were nearly twice thicker than under standard conditions, while no difference was observed for tissues produced from dermal fibroblasts. The increased matrix deposition was not correlated with an increased proliferation of ASCs, or by higher transcript levels of fibronectin or collagens I and III. A 30% increase of type V collagen mRNA was observed. Interestingly, tissues engineered from dermal fibroblasts featured a four-fold higher level of MMP-1 transcripts under dynamic conditions. Mechanical properties were similar for tissues reconstructed using dynamic or static conditions. Finally, cell sheets produced using ASCs under dynamic conditions could readily be manipulated, resulting in a 2 week reduction of the production time (from 5 to 3 weeks). Our results describe a distinctive property of ASCs' response to media motion, indicating that their culture under dynamic conditions leads to optimized tissue engineering. Copyright © 2011 John Wiley & Sons, Ltd.

Mechanical design of the first proximal Ig domain of human cardiac titin revealed by single molecule force spectroscopy.

PubMed

Li, Hongbin; Fernandez, Julio M

2003-11-14

The elastic I-band part of muscle protein titin contains two tandem immunoglobulin (Ig) domain regions of distinct mechanical properties. Until recently, the only known structure was that of the I27 module of the distal region, whose mechanical properties have been reported in detail. Recently, the structure of the first proximal domain, I1, has been resolved at 2.1A. In addition to the characteristic beta-sandwich structure of all titin Ig domains, the crystal structure of I1 showed an internal disulfide bridge that was proposed to modulate its mechanical extensibility in vivo. Here, we use single molecule force spectroscopy and protein engineering to examine the mechanical architecture of this domain. In contrast to the predictions made from the X-ray crystal structure, we find that the formation of a disulfide bridge in I1 is a relatively rare event in solution, even under oxidative conditions. Furthermore, our studies of the mechanical stability of I1 modules engineered with point mutations reveal significant differences between the mechanical unfolding of the I1 and I27 modules. Our study illustrates the varying mechanical architectures of the titin Ig modules.

Practical Guide to HVAC for Schools.

ERIC Educational Resources Information Center

ASHRAE Journal, 1998

1998-01-01

Features six articles on heating, ventilation, and air-conditioning systems for schools. Examines how to avoid air temperature complaints when choosing a system; special system features; engineers, indoor air quality, and schools; mechanical systems noise in classrooms; operation and management issues related to design; and details on bids and…

Challenges in Predicting Planetary Granular Mechanics

NASA Technical Reports Server (NTRS)

Metzger, Philip T.

2005-01-01

Through the course of human history, our needs in agriculture, habitat construction, and resource extraction have driven us to gain more experience working with the granular materials of planet Earth than with any other type of substance in nature, with the possible exception being water. Furthermore, throughout the past two centuries we have seen a dramatic and ever growing interest among scientists and engineers to understand and predict both its static and rheological properties. Ironically, however, despite this wealth of experience we still do not have a fundamental understanding of the complex physical phenomena that emerge even as just ordinary sand is shaken, squeezed or poured. As humanity is now reaching outward through the solar system, not only robotic ally but also with our immediate human presence, the need to understand and predict granular mechanics has taken on a new dimension. We must learn to farm, build and mine the regoliths of other planets where the environmental conditions are different than on Earth, and we are rapidly discovering that the effects of these environmental conditions are not trivial. Some of the relevant environmental features include the regolith formation processes throughout a planet's geologic and hydrologic history, the unknown mixtures of volatiles residing within the soil, the relative strength of gravitation, d the atm9spheric pressure and its seasonal variations. The need to work with soils outside our terrestrial experience base provides us with both a challenge and an opportunity. The challenge is to learn how to extrapolate our experience into these new planetary conditions, enabling the engineering decisions that are needed right now as we take the next few steps in solar system exploration. The opportunity is to use these new planetary environments as laboratories that will help us to see granular mechanics in new ways, to challenge our assumptions, and to help us finally unravel the elusive physics that lie behind complex granular phenomena. Toward these goals, a workshop was held recently at NASA's John F. Kennedy Space Center, attracting over a hundred scientists and engineers from around the world and from a broad crosssection of scientific and engineering disciplines. This talk will provide an out-briefing from that workshop, communicating some of its early findings in regard to lunar and Martian exploration: (1) the requirements for working with granular materials, (2) the challenges that granular materials will pose, (3) the environmental conditions that affect granular mechanics, (4) instruments and measurements that are needed on the Moon and Mars to support granular material research, and (5) some of the possible research avenues that should be pursued.

Genetically engineered mouse models for studying inflammatory bowel disease.

PubMed

Mizoguchi, Atsushi; Takeuchi, Takahito; Himuro, Hidetomo; Okada, Toshiyuki; Mizoguchi, Emiko

2016-01-01

Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory condition that is mediated by very complex mechanisms controlled by genetic, immune, and environmental factors. More than 74 kinds of genetically engineered mouse strains have been established since 1993 for studying IBD. Although mouse models cannot fully reflect human IBD, they have provided significant contributions for not only understanding the mechanism, but also developing new therapeutic means for IBD. Indeed, 20 kinds of genetically engineered mouse models carry the susceptibility genes identified in human IBD, and the functions of some other IBD susceptibility genes have also been dissected out using mouse models. Cutting-edge technologies such as cell-specific and inducible knockout systems, which were recently employed to mouse IBD models, have further enhanced the ability of investigators to provide important and unexpected rationales for developing new therapeutic strategies for IBD. In this review article, we briefly introduce 74 kinds of genetically engineered mouse models that spontaneously develop intestinal inflammation. Copyright © 2015 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

Quantitative Ultrasonic Evaluation of Mechanical Properties of Engineering Materials

NASA Technical Reports Server (NTRS)

Vary, A.

1978-01-01

Progress in the application of ultrasonic techniques to nondestructive measurement of mechanical strength of engineering materials is reviewed. A dormant concept in nondestructive evaluation (NDE) is invoked. The availability of ultrasonic methods that can be applied to actual parts to assess their potential susceptibility to failure under design conditions is discussed. It was shown that ultrasonic methods yield measurements of elastic moduli, microstructure, hardness, fracture toughness, tensile strength, yield strength, and shear strength for a wide range of materials (including many types of metals, ceramics, and fiber composites). It was also indicated that although most of these methods were shown feasible in laboratory studies, more work is needed before they can be used on actual parts in processing, assembly, inspection, and maintenance lines.

Metabolic Regulation of a Bacterial Cell System with Emphasis on Escherichia coli Metabolism

PubMed Central

Shimizu, Kazuyuki

2013-01-01

It is quite important to understand the overall metabolic regulation mechanism of bacterial cells such as Escherichia coli from both science (such as biochemistry) and engineering (such as metabolic engineering) points of view. Here, an attempt was made to clarify the overall metabolic regulation mechanism by focusing on the roles of global regulators which detect the culture or growth condition and manipulate a set of metabolic pathways by modulating the related gene expressions. For this, it was considered how the cell responds to a variety of culture environments such as carbon (catabolite regulation), nitrogen, and phosphate limitations, as well as the effects of oxygen level, pH (acid shock), temperature (heat shock), and nutrient starvation. PMID:25937963

Deformation mechanism of CrN/nitriding coated steel in wear and nano-scratch experiments under heavy loading conditions

NASA Astrophysics Data System (ADS)

Wang, Yongguang; Chen, Yao; Zhao, Dong; Lu, Xiaolong; Liu, Weiwei; Qi, Fei; Chen, Yang

2018-07-01

CrN coatings are widely used to protect metals from wear in industrial engineering. However, fundamental deformation mechanism of these coatings under heavy loading conditions remains elusive. In this paper, multilayered hard coatings with a CrN matrix and a supporting layer were developed by means of the hybrid deposition process combined with PVD and ionicnitriding. The tribological behavior of coatings with and without ionicnitriding were investigated by a pin-on-disk arrangement under heavy loading conditions. In addition, the deformation mechanism of the multilayered hard coatings was studied by nano-scratch experiment with ramp load model, which has not been discussed previously. It was found that the deformation process of coatings could be divided into three regimes based on the evolution of frictional coefficient. The insertion of nitriding films leads to the further increase in frictional resistance owing to the elastic-plastic deformation. The results and analysis reveal some insights into the coating design for multilayered hard coatings with the consideration of deformation mechanisms.

Oxidation- and Creep-Enhanced Fatigue of Haynes 188 Alloy-Oxide Scale System Under Simulated Pulse Detonation Engine Conditions

NASA Technical Reports Server (NTRS)

Zhu, Dongming; Fox, Dennis S.; Miller, Robert A.

2002-01-01

The development of the pulse detonation engine (PDE) requires robust design of the engine components that are capable of enduring harsh detonation environments. In this study, a high cycle thermal fatigue test rig was developed for evaluating candidate PDE combustor materials using a CO2 laser. The high cycle thermal fatigue behavior of Haynes 188 alloy was investigated under an enhanced pulsed laser test condition of 30 Hz cycle frequency (33 ms pulse period, and 10 ms pulse width including 0.2 ms pulse spike). The temperature swings generated by the laser pulses near the specimen surface were characterized by using one-dimensional finite difference modeling combined with experimental measurements. The temperature swings resulted in significant thermal cyclic stresses in the oxide scale/alloy system, and induced extensive surface cracking. Striations of various sizes were observed at the cracked surfaces and oxide/alloy interfaces under the cyclic stresses. The test results indicated that oxidation and creep-enhanced fatigue at the oxide scale/alloy interface was an important mechanism for the surface crack initiation and propagation under the simulated PDE condition.

Conceptual modeling for identification of worst case conditions in environmental risk assessment of nanomaterials using nZVI and C60 as case studies.

PubMed

Grieger, Khara D; Hansen, Steffen F; Sørensen, Peter B; Baun, Anders

2011-09-01

Conducting environmental risk assessment of engineered nanomaterials has been an extremely challenging endeavor thus far. Moreover, recent findings from the nano-risk scientific community indicate that it is unlikely that many of these challenges will be easily resolved in the near future, especially given the vast variety and complexity of nanomaterials and their applications. As an approach to help optimize environmental risk assessments of nanomaterials, we apply the Worst-Case Definition (WCD) model to identify best estimates for worst-case conditions of environmental risks of two case studies which use engineered nanoparticles, namely nZVI in soil and groundwater remediation and C(60) in an engine oil lubricant. Results generated from this analysis may ultimately help prioritize research areas for environmental risk assessments of nZVI and C(60) in these applications as well as demonstrate the use of worst-case conditions to optimize future research efforts for other nanomaterials. Through the application of the WCD model, we find that the most probable worst-case conditions for both case studies include i) active uptake mechanisms, ii) accumulation in organisms, iii) ecotoxicological response mechanisms such as reactive oxygen species (ROS) production and cell membrane damage or disruption, iv) surface properties of nZVI and C(60), and v) acute exposure tolerance of organisms. Additional estimates of worst-case conditions for C(60) also include the physical location of C(60) in the environment from surface run-off, cellular exposure routes for heterotrophic organisms, and the presence of light to amplify adverse effects. Based on results of this analysis, we recommend the prioritization of research for the selected applications within the following areas: organism active uptake ability of nZVI and C(60) and ecotoxicological response end-points and response mechanisms including ROS production and cell membrane damage, full nanomaterial characterization taking into account detailed information on nanomaterial surface properties, and investigations of dose-response relationships for a variety of organisms. Copyright © 2011 Elsevier B.V. All rights reserved.

Engineering principles to assure compatible docking between future spacecraft of USA and USSR

NASA Technical Reports Server (NTRS)

Johnson, C. C.

1975-01-01

Working jointly the USA and the USSR have selected an androgynous, peripheral type docking mechanism concept. The mechanical principles inherent to the concept, the rationale supporting its selection, and the probable nature of future designs stemming from the concept, are described. Operational situations just prior to docking, impact conditions, energy absorption, and the structural joining of the spacecraft, are specified. Docking procedures for the Apollo-Soyuz missions are discussed.

A New, Highly Improved Two-Cycle Engine

NASA Technical Reports Server (NTRS)

Wiesen, Bernard

2008-01-01

The figure presents a cross-sectional view of a supercharged, variable-compression, two-cycle, internal-combustion engine that offers significant advantages over prior such engines. The improvements are embodied in a combination of design changes that contribute synergistically to improvements in performance and economy. Although the combination of design changes and the principles underlying them are complex, one of the main effects of the changes on the overall engine design is reduced (relative to prior two-cycle designs) mechanical complexity, which translates directly to reduced manufacturing cost and increased reliability. Other benefits include increases in the efficiency of both scavenging and supercharging. The improvements retain the simplicity and other advantages of two-cycle engines while affording increases in volumetric efficiency and performance across a wide range of operating conditions that, heretofore have been accessible to four-cycle engines but not to conventionally scavenged two-cycle ones, thereby increasing the range of usefulness of the two-cycle engine into all areas now dominated by the four-cycle engine. The design changes and benefits are too numerous to describe here in detail, but it is possible to summarize the major improvements: Reciprocating Shuttle Inlet Valve The entire reciprocating shuttle inlet valve and its operating gear is constructed as a single member. The shuttle valve is actuated in a lost-motion arrangement in which, at the ends of its stroke, projections on the shuttle valve come to rest against abutments at the ends of grooves in a piston skirt. This shuttle-valve design obviates the customary complex valve mechanism, actuated from an engine crankshaft or camshaft, yet it is effective with every type of two-cycle engine, from small high-speed single cylinder model engines, to large low-speed multiple cylinder engines.

Test Rig for Evaluating Active Turbine Blade Tip Clearance Control Concepts

NASA Technical Reports Server (NTRS)

Lattime, Scott B.; Steinetz, Bruce M.; Robbie, Malcolm G.

2003-01-01

Improved blade tip sealing in the high pressure compressor and high pressure turbine can provide dramatic improvements in specific fuel consumption, time-on-wing, compressor stall margin and engine efficiency as well as increased payload and mission range capabilities of both military and commercial gas turbine engines. The preliminary design of a mechanically actuated active clearance control (ACC) system for turbine blade tip clearance management is presented along with the design of a bench top test rig in which the system is to be evaluated. The ACC system utilizes mechanically actuated seal carrier segments and clearance measurement feedback to provide fast and precise active clearance control throughout engine operation. The purpose of this active clearance control system is to improve upon current case cooling methods. These systems have relatively slow response and do not use clearance measurement, thereby forcing cold build clearances to set the minimum clearances at extreme operating conditions (e.g., takeoff, re-burst) and not allowing cruise clearances to be minimized due to the possibility of throttle transients (e.g., step change in altitude). The active turbine blade tip clearance control system design presented herein will be evaluated to ensure that proper response and positional accuracy is achievable under simulated high-pressure turbine conditions. The test rig will simulate proper seal carrier pressure and temperature loading as well as the magnitudes and rates of blade tip clearance changes of an actual gas turbine engine. The results of these evaluations will be presented in future works.

Lyophilized Silk Sponges: A Versatile Biomaterial Platform for Soft Tissue Engineering

PubMed Central

2015-01-01

We present a silk biomaterial platform with highly tunable mechanical and degradation properties for engineering and regeneration of soft tissues such as, skin, adipose, and neural tissue, with elasticity properties in the kilopascal range. Lyophilized silk sponges were prepared under different process conditions and the effect of silk molecular weight, concentration and crystallinity on 3D scaffold formation, structural integrity, morphology, mechanical and degradation properties, and cell interactions in vitro and in vivo were studied. Tuning the molecular weight distribution (via degumming time) of silk allowed the formation of stable, highly porous, 3D scaffolds that held form with silk concentrations as low as 0.5% wt/v. Mechanical properties were a function of silk concentration and scaffold degradation was driven by beta-sheet content. Lyophilized silk sponges supported the adhesion of mesenchymal stem cells throughout 3D scaffolds, cell proliferation in vitro, and cell infiltration and scaffold remodeling when implanted subcutaneously in vivo. PMID:25984573

Reverse engineering the cooperative machinery of human hemoglobin.

PubMed

Ren, Zhong

2013-01-01

Hemoglobin transports molecular oxygen from the lungs to all human tissues for cellular respiration. Its α2β2 tetrameric assembly undergoes cooperative binding and releasing of oxygen for superior efficiency and responsiveness. Over past decades, hundreds of hemoglobin structures were determined under a wide range of conditions for investigation of molecular mechanism of cooperativity. Based on a joint analysis of hemoglobin structures in the Protein Data Bank (Ren, companion article), here I present a reverse engineering approach to elucidate how two subunits within each dimer reciprocate identical motions that achieves intradimer cooperativity, how ligand-induced structural signals from two subunits are integrated to drive quaternary rotation, and how the structural environment at the oxygen binding sites alter their binding affinity. This mechanical model reveals the intricate design that achieves the cooperative mechanism and has previously been masked by inconsistent structural fluctuations. A number of competing theories on hemoglobin cooperativity and broader protein allostery are reconciled and unified.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Slattery, Stuart R

ExaMPM is a mini-application for the Material Point Method (MPM) for studying the application of MPM to future exascale computing systems. MPM is a general method for computational mechanics and fluids and is used in a wide variety of science and engineering disciplines to study problems with large deformations, phase change, fracture, and other phenomena. ExaMPM provides a reference implementation of MPM as described in the 1994 work of Sulsky et.al. (Sulsky, Deborah, Zhen Chen, and Howard L. Schreyer. "A particle method for history-dependent materials." Computer methods in applied mechanics and engineering 118.1-2 (1994): 179-196.). The software can solve basicmore » MPM problems in solid mechanics using the original algorithm of Sulsky with explicit time integration, basic geometries, and free-slip and no-slip boundary conditions as described in the reference. ExaMPM is intended to be used as a starting point to design new parallel algorithms for the next generation of DOE supercomputers.« less

Controlled growth factor release from synthetic extracellular matrices

NASA Astrophysics Data System (ADS)

Lee, Kuen Yong; Peters, Martin C.; Anderson, Kenneth W.; Mooney, David J.

2000-12-01

Polymeric matrices can be used to grow new tissues and organs, and the delivery of growth factors from these matrices is one method to regenerate tissues. A problem with engineering tissues that exist in a mechanically dynamic environment, such as bone, muscle and blood vessels, is that most drug delivery systems have been designed to operate under static conditions. We thought that polymeric matrices, which release growth factors in response to mechanical signals, might provide a new approach to guide tissue formation in mechanically stressed environments. Critical design features for this type of system include the ability to undergo repeated deformation, and a reversible binding of the protein growth factors to polymeric matrices to allow for responses to repeated stimuli. Here we report a model delivery system that can respond to mechanical signalling and upregulate the release of a growth factor to promote blood vessel formation. This approach may find a number of applications, including regeneration and engineering of new tissues and more general drug-delivery applications.

Impact Mechanics

NASA Astrophysics Data System (ADS)

Stronge, W. J.

2004-03-01

Impact mechanics is concerned with the reaction forces that develop during a collision and the dynamic response of structures to these reaction forces. The subject has a wide range of engineering applications, from designing sports equipment to improving the crashworthiness of automobiles. This book develops several different methodologies for analysing collisions between structures. These range from rigid body theory for structures that are stiff and compact, to vibration and wave analyses for flexible structures. The emphasis is on low-speed impact where damage is local to the small region of contact between the colliding bodies. The analytical methods presented give results that are more robust or less sensitive to initial conditions than have been achieved hitherto. As a text, Impact Mechanics builds upon foundation courses in dynamics and strength of materials. It includes numerous industrially relevant examples and end-of-chapter homework problems drawn from industry and sports. Practising engineers will also find the methods presented in this book useful in calculating the response of a mechanical system to impact.

Evolutionary mechanics: new engineering principles for the emergence of flexibility in a dynamic and uncertain world.

PubMed

Whitacre, James M; Rohlfshagen, Philipp; Bender, Axel; Yao, Xin

2012-09-01

Engineered systems are designed to deftly operate under predetermined conditions yet are notoriously fragile when unexpected perturbations arise. In contrast, biological systems operate in a highly flexible manner; learn quickly adequate responses to novel conditions, and evolve new routines and traits to remain competitive under persistent environmental change. A recent theory on the origins of biological flexibility has proposed that degeneracy-the existence of multi-functional components with partially overlapping functions-is a primary determinant of the robustness and adaptability found in evolved systems. While degeneracy's contribution to biological flexibility is well documented, there has been little investigation of degeneracy design principles for achieving flexibility in systems engineering. Actually, the conditions that can lead to degeneracy are routinely eliminated in engineering design. With the planning of transportation vehicle fleets taken as a case study, this article reports evidence that degeneracy improves the robustness and adaptability of a simulated fleet towards unpredicted changes in task requirements without incurring costs to fleet efficiency. We find that degeneracy supports faster rates of design adaptation and ultimately leads to better fleet designs. In investigating the limitations of degeneracy as a design principle, we consider decision-making difficulties that arise from degeneracy's influence on fleet complexity. While global decision-making becomes more challenging, we also find degeneracy accommodates rapid distributed decision-making leading to (near-optimal) robust system performance. Given the range of conditions where favorable short-term and long-term performance outcomes are observed, we propose that degeneracy may fundamentally alter the propensity for adaptation and is useful within different engineering and planning contexts.

Polarization of perceived Procedural Justice.

PubMed

Flint, Douglas H; Hernandez-Marrero, Pablo; Wielemaker, Martin

2006-02-01

This study examined polarization of perceptions of Procedural Justice. Two polarization mechanisms are examined, Persuasive Arguments and Social Comparisons. Participants were students enrolled in a first-year introductory business class. There were 216 participants in the Persuasive Arguments study, 429 in the Social Comparisons study. The average age of all participants was 22.3 yr. (SD = 2.1); 56% were women. Fields of study represented were business, engineering, information technology, and sports. Analysis showed under conditions of low Procedural Justice, polarization effects were only found with the Persuasive Arguments mechanism. Under conditions of high Procedural Justice, polarization effects were only found with Social Comparisons. Implications for group polarization and Procedural Justice theories are considered.

The effect of preparation conditions on the structure and mechanical properties of reaction-sintered silicon nitride

NASA Technical Reports Server (NTRS)

Heinrich, J.

1980-01-01

The microstructure of reaction sintered silicon nitride (RSSN) was changed over a wide range by varying the grain density, grain size of the silicon starting powder, nitriding conditions, and by introducing artificial pores. The influence of single microstructural parameters on mechanical properties like room temperature strength, creep behavior, and resistance to thermal shock was investigated. The essential factors influencing these properties were found to be total porosity, pore size distribution, and the fractions of alpha and beta Si3N4. In view of high temperature engineering applications of RSSN, potentials for optimizing the material's properties by controlled processing are discussed.

Overview of Icing Research at NASA Glenn

NASA Technical Reports Server (NTRS)

Kreeger, Richard E.

2013-01-01

The aviation industry continues to deal with icing-related incidents and accidents on a regular basis. Air traffic continues to increase, placing more aircraft in adverse icing conditions more frequently and for longer periods. Icing conditions once considered rare or of little consequence, such as super-cooled large droplet icing or high altitude ice crystals, have emerged as major concerns for modern aviation. Because of this, there is a need to better understand the atmospheric environment, the fundamental mechanisms and characteristics of ice growth, and the aerodynamic effects due to icing, as well as how best to protect these aircraft. The icing branch at NASA Glenn continues to develop icing simulation methods and engineering tools to address current aviation safety issues in airframe, engine and rotorcraft icing.

46 CFR 12.15-13 - Deck engine mechanic.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Deck engine mechanic. 12.15-13 Section 12.15-13 Shipping... ENDORSEMENTS Qualified Member of the Engine Department § 12.15-13 Deck engine mechanic. (a) An applicant for an endorsement as deck engine mechanic shall be a person holding an MMC or MMD endorsed as junior engineer. The...

46 CFR 12.15-13 - Deck engine mechanic.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Deck engine mechanic. 12.15-13 Section 12.15-13 Shipping... ENDORSEMENTS Qualified Member of the Engine Department § 12.15-13 Deck engine mechanic. (a) An applicant for an endorsement as deck engine mechanic shall be a person holding an MMC or MMD endorsed as junior engineer. The...

46 CFR 12.15-13 - Deck engine mechanic.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Deck engine mechanic. 12.15-13 Section 12.15-13 Shipping... ENDORSEMENTS Qualified Member of the Engine Department § 12.15-13 Deck engine mechanic. (a) An applicant for an endorsement as deck engine mechanic shall be a person holding an MMC or MMD endorsed as junior engineer. The...

46 CFR 12.15-13 - Deck engine mechanic.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Deck engine mechanic. 12.15-13 Section 12.15-13 Shipping... ENDORSEMENTS Qualified Member of the Engine Department § 12.15-13 Deck engine mechanic. (a) An applicant for an endorsement as deck engine mechanic shall be a person holding an MMC or MMD endorsed as junior engineer. The...

Moire strain analysis of paper

Treesearch

R. E. Rowlands; P. K. Beasley; D. E. Gunderson

1983-01-01

Efficient use of paper products involves using modern aspects of materials science and engineering mechanics. This implies the ability to determine simultaneously different components of strain at multiple locations and under static or dynamic conditions. Although measuring strains in paper has been a topic of interest for over 40 years, present capability remains...

Thermal-mechanical fatigue behavior of nickel-base superalloys

NASA Technical Reports Server (NTRS)

Pelloux, R. M.; Marchand, N.

1986-01-01

The main achievements of a 36-month research program are presented. The main objective was to gain more insight into the problem of crack growth under thermal mechanical fatigue (TMF) conditions. This program was conducted at M.I.T. for the period of September 1982 to September 1985. The program was arranged into five technical tasks. Under Task I, the literature of TMF data was reviewed. The goal was to identify the crack propagation conditions in aircraft engines (hot section) and to assess the validity of conventional fracture mechanics parameters to address TMF crack growth. The second task defined the test facilities, test specimen and the testing conditions needed to establish the effectiveness of data correlation parameters identified in Task I. Three materials (Inconel X-750, Hastelloy-X, and B-1900) were chosen for the program. Task II was accomplished in collaboration with Pratt & Whitney Aircraft engineers. Under Task III, a computerized testing system to measure the TMF behavior (LCF and CG behaviors) of various alloys systems was built. The software used to run isothermal and TMF tests was also developed. Built around a conventional servohydraulic machine, the system is capable of push-pull tests under stress or strain and temperature controlled conditions in the temperature range of 25C to 1050C. A crack propagation test program was defined and conducted under Task IV. The test variables included strain range, strain rate (frequency) and temperature. Task V correlated and generalized the Task IV data for isothermal and variable temperature conditions so that several crack propagation parameters could be compared and evaluated. The structural damage (mode of cracking and dislocation substructure) under TMF cycling was identified and contrasted with the isothermal damage to achieve a sound fundamental mechanistic understanding of TMF.

Evaluation of coupling approaches for thermomechanical simulations

DOE PAGES

Novascone, S. R.; Spencer, B. W.; Hales, J. D.; ...

2015-08-10

Many problems of interest, particularly in the nuclear engineering field, involve coupling between the thermal and mechanical response of an engineered system. The strength of the two-way feedback between the thermal and mechanical solution fields can vary significantly depending on the problem. Contact problems exhibit a particularly high degree of two-way feedback between those fields. This paper describes and demonstrates the application of a flexible simulation environment that permits the solution of coupled physics problems using either a tightly coupled approach or a loosely coupled approach. In the tight coupling approach, Newton iterations include the coupling effects between all physics,more » while in the loosely coupled approach, the individual physics models are solved independently, and fixed-point iterations are performed until the coupled system is converged. These approaches are applied to simple demonstration problems and to realistic nuclear engineering applications. The demonstration problems consist of single and multi-domain thermomechanics with and without thermal and mechanical contact. Simulations of a reactor pressure vessel under pressurized thermal shock conditions and a simulation of light water reactor fuel are also presented. Here, problems that include thermal and mechanical contact, such as the contact between the fuel and cladding in the fuel simulation, exhibit much stronger two-way feedback between the thermal and mechanical solutions, and as a result, are better solved using a tight coupling strategy.« less

46 CFR 113.35-9 - Mechanical engine order telegraph systems.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Mechanical engine order telegraph systems. 113.35-9... COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-9 Mechanical engine order telegraph systems. (a) Each mechanical engine order telegraph system must consist of transmitters and...

Opportunities in Mechnical Engineering. [VGM Career Horizons Series].

ERIC Educational Resources Information Center

Konzo, Seichi; Bayne, James W.

This book presents information on career opportunities in mechanical engineering. Chapter 1 describes the historical development of mechanical engineering and its interactions with society, considers the growth of the American Society of Mechanical Engineers, and discusses the relevance of mechanical engineering to present-day and future society.…

Adaptive laboratory evolution of ethanologenic Zymomonas mobilis strain tolerant to furfural and acetic acid inhibitors.

PubMed

Shui, Zong-Xia; Qin, Han; Wu, Bo; Ruan, Zhi-yong; Wang, Lu-shang; Tan, Fu-Rong; Wang, Jing-Li; Tang, Xiao-Yu; Dai, Li-Chun; Hu, Guo-Quan; He, Ming-Xiong

2015-07-01

Furfural and acetic acid from lignocellulosic hydrolysates are the prevalent inhibitors to Zymomonas mobilis during cellulosic ethanol production. Developing a strain tolerant to furfural or acetic acid inhibitors is difficul by using rational engineering strategies due to poor understanding of their underlying molecular mechanisms. In this study, strategy of adaptive laboratory evolution (ALE) was used for development of a furfural and acetic acid-tolerant strain. After three round evolution, four evolved mutants (ZMA7-2, ZMA7-3, ZMF3-2, and ZMF3-3) that showed higher growth capacity were successfully obtained via ALE method. Based on the results of profiling of cell growth, glucose utilization, ethanol yield, and activity of key enzymes, two desired strains, ZMA7-2 and ZMF3-3, were achieved, which showed higher tolerance under 7 g/l acetic acid and 3 g/l furfural stress condition. Especially, it is the first report of Z. mobilis strain that could tolerate higher furfural. The best strain, Z. mobilis ZMF3-3, has showed 94.84% theoretical ethanol yield under 3-g/l furfural stress condition, and the theoretical ethanol yield of ZM4 is only 9.89%. Our study also demonstrated that ALE method might also be used as a powerful metabolic engineering tool for metabolic engineering in Z. mobilis. Furthermore, the two best strains could be used as novel host for further metabolic engineering in cellulosic ethanol or future biorefinery. Importantly, the two strains may also be used as novel-tolerant model organisms for the genetic mechanism on the "omics" level, which will provide some useful information for inverse metabolic engineering.

Biofluid Mechanics Education at U Michigan

NASA Astrophysics Data System (ADS)

Grotberg, James

2007-11-01

At the University of Michigan, biofluid mechanics is taught in the Department of Biomedical Engineering with cross-listing in Mechanical Engineering. The course has evolved over 25 years and serves advanced undergraduates and graduate students. The course description is as follows: BiomedE/MechE 476 Biofluid Mechanics. CATALOG DESCRIPTION: This is an intermediate level fluid mechanics course which uses examples from biotechnology processes and physiologic applications including cellular, cardiovascular, respiratory, ocular, renal, orthopedic, and gastrointestinal systems. COURSE TOPICS: 1. Dimensional analysis (gastrointestinal, renal) 2. Approximation methods, numerical methods (biotechnology, respiratory) 3. Particle kinematics in Eulerian and Lagrangian references frames (biotechnology, respiratory) 4. Conservation of mass and momentum 5. Constitutive equations (blood, mucus) 6. Kinematic and stress boundary conditions: rigid, flexible, porous (cardio-pulmonary, cellular) 7. Surface tension phenomena (pulmonary, ocular) 8. Flow and wave propagation in flexible tubes (cardio-pulmonary) 9. Oscillatory and pulsatile flows (cardio-pulmonary, orthopedic) 10. High Reynolds number flows (cardio-pulmonary) 11. Low Reynolds number flows (biotechnology, cellular, vascular) 12. Lubrication theory (vascular, orthopedic) 13. Flow in poroelastic media (orthopedic, pulmonary, ocular) 14. Video presentations of laboratory experiments.

Joint measurements of black carbon and particle mass for heavy-duty diesel vehicles using a portable emission measurement system

NASA Astrophysics Data System (ADS)

Zheng, Xuan; Wu, Ye; Zhang, Shaojun; Baldauf, Richard W.; Zhang, K. Max; Hu, Jingnan; Li, Zhenhua; Fu, Lixin; Hao, Jiming

2016-09-01

The black carbon (BC) emitted from heavy-duty diesel vehicles (HDDVs) is an important source of urban atmospheric pollution and creates strong climate-forcing impacts. The emission ratio of BC to total particle mass (PM) (i.e., BC/PM ratio) is an essential variable used to estimate total BC emissions from historical PM data; however, these ratios have not been measured using portable emission measurement systems (PEMS) in order to obtain real-world measurements over a wide range of driving conditions. In this study, we developed a PEMS platform by integrating two Aethalometers and an electric low pressure impactor to realize the joint measurement of real-world BC and PM emissions for ten HDDVs in China. Test results showed that the average BC/PM ratio for five HDDVs equipped with mechanical fuel injection (MI) engines was 0.43 ± 0.06, significantly lower (P < 0.05) than another five HDDVs equipped with electronically-controlled fuel injection (EI) engines (0.56 ± 0.12). Traffic conditions also affected the BC/PM ratios with higher ratios on freeway routes than on local roads. Furthermore, higher ratios were observed for HDDVs equipped with EI engines than for the MI engines for the highway and local road routes. With an operating mode binning approach, we observed that the instantaneous BC/PM ratios of EI engine vehicles were above those of the MI engine vehicles in all operating modes except for the braking mode (i.e., Bin 0). Therefore, the complex impacts from engine technology and traffic conditions on BC/PM ratios should be carefully considered when estimating real-world BC emissions from HDDVs based on overall PM emissions data.

Advanced Turbine Technology Applications Project (ATTAP)

NASA Technical Reports Server (NTRS)

1991-01-01

This report summarizes work performed in support of the development and demonstration of a structural ceramic technology for automotive gas turbine engines. The AGT101 regenerated gas turbine engine developed under the previous DOE/NASA Advanced Gas Turbine (AGT) program is being utilized for verification testing of the durability of next-generation ceramic components and their suitability for service at reference powertrain design conditions. Topics covered in this report include ceramic processing definition and refinement, design improvements to the test bed engine and test rigs, and design methodologies related to ceramic impact and fracture mechanisms. Appendices include reports by ATTAP subcontractors addressing the development of silicon nitride and silicon carbide families of materials and processes.

46 CFR 113.35-15 - Mechanical engine order telegraph systems; application.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Mechanical engine order telegraph systems; application...-15 Mechanical engine order telegraph systems; application. If a mechanical engine order telegraph... cables or other mechanical limitations must not prevent the efficient operation of the system. ...

Under pressure: evolutionary engineering of yeast strains for improved performance in fuels and chemicals production.

PubMed

Mans, Robert; Daran, Jean-Marc G; Pronk, Jack T

2018-04-01

Evolutionary engineering, which uses laboratory evolution to select for industrially relevant traits, is a popular strategy in the development of high-performing yeast strains for industrial production of fuels and chemicals. By integrating whole-genome sequencing, bioinformatics, classical genetics and genome-editing techniques, evolutionary engineering has also become a powerful approach for identification and reverse engineering of molecular mechanisms that underlie industrially relevant traits. New techniques enable acceleration of in vivo mutation rates, both across yeast genomes and at specific loci. Recent studies indicate that phenotypic trade-offs, which are often observed after evolution under constant conditions, can be mitigated by using dynamic cultivation regimes. Advances in research on synthetic regulatory circuits offer exciting possibilities to extend the applicability of evolutionary engineering to products of yeasts whose synthesis requires a net input of cellular energy. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Application of single crystal superalloys for Earth-to-orbit propulsion systems

NASA Technical Reports Server (NTRS)

Dreshfield, R. L.; Parr, R. A.

1987-01-01

Single crystal superalloys were first identified as potentially useful engineering materials for aircraft gas turbine engines in the mid-1960's. Although they were not introduced into service as turbine blades in commercial aircraft engines until the early 1980's, they have subsequently accumulated tens of millions of flight hours in revenue producing service. The space shuttle main engine (SSME) and potential advanced earth-to-orbit propulsion systems impose severe conditions on turbopump turbine blades which for some potential failure modes are more severe than in aircraft gas turbines. Research activities which are directed at evaluating the potential for single crystal superalloys for application as turbopump turbine blades in the SSME and advanced rocket engines are discussed. The mechanical properties of these alloys are summarized and the effects of hydrogen are noted. The use of high gradient directional solidification and hot isostatic pressing to improve fatigue properties is also addressed.

Research progress of microbial corrosion of reinforced concrete structure

NASA Astrophysics Data System (ADS)

Li, Shengli; Li, Dawang; Jiang, Nan; Wang, Dongwei

2011-04-01

Microbial corrosion of reinforce concrete structure is a new branch of learning. This branch deals with civil engineering , environment engineering, biology, chemistry, materials science and so on and is a interdisciplinary area. Research progress of the causes, research methods and contents of microbial corrosion of reinforced concrete structure is described. The research in the field is just beginning and concerted effort is needed to go further into the mechanism of reinforce concrete structure and assess the security and natural life of reinforce concrete structure under the special condition and put forward the protective methods.

Hyaluronan hydrogels with a low degree of modification as scaffolds for cartilage engineering.

PubMed

La Gatta, Annalisa; Ricci, Giulia; Stellavato, Antonietta; Cammarota, Marcella; Filosa, Rosanna; Papa, Agata; D'Agostino, Antonella; Portaccio, Marianna; Delfino, Ines; De Rosa, Mario; Schiraldi, Chiara

2017-10-01

In the field of cartilage engineering, continuing efforts have focused on fabricating scaffolds that favor maintenance of the chondrocytic phenotype and matrix formation, in addition to providing a permeable, hydrated, microporous structure and mechanical support. The potential of hyaluronan-based hydrogels has been well established, but the ideal matrix remains to be developed. This study describes the development of hyaluronan sponges-based scaffolds obtained by lysine methyl-ester crosslinking. The reaction conditions are optimized with minimal chemical modifications to obtain materials that closely resemble elements in physiological cellular environments. Three hydrogels with different amounts of crosslinkers were produced that show morphological, water-uptake, mechanical, and stability properties comparable or superior to those of currently available hyaluronan-scaffolds, but with significantly fewer hyaluronan modifications. Primary human chondrocytes cultured with the most promising hydrogel were viable and maintained lineage identity for 3 weeks. They also secreted cartilage-specific matrix proteins. These scaffolds represent promising candidates for cartilage engineering. Copyright © 2017 Elsevier B.V. All rights reserved.

A Summary of the Naval Postgraduate School Research Program.

DTIC Science & Technology

1984-06-01

Administrative Sciences, Operations Research, National Security Affairs, Physics, Electrical Engineering , Meterology, Aeronautics, Oceanography and Mechanical ...Oceans and Major Seas -------------------------------- 290 DEPARTMENT OF MECHANICAL ENGINEERING 291 Mechanical Engineering Department Summary 293...in Buried Pipes Using Sulphur Hexaflouride as a Tracer Gas," American Society of Mechanical Engineers , The Journal of Engineering for Power

Evaluation of an innovative high temperature ceramic wafer seal for hypersonic engine applications. Ph.D. Thesis, 1991

NASA Technical Reports Server (NTRS)

Steinetz, Bruce M.

1992-01-01

A critical mechanical system in advanced hypersonic engines is the panel-edge seal system that seals gaps between the articulating engine panels and the adjacent engine splitter walls. Significant advancements in seal technology are required to meet the extreme demands placed on the seals, including the simultaneous requirements of low leakage, conformable, high temperature, high pressure, sliding operation. In this investigation, the design, development, analytical and experimental evaluation of a new ceramic wafer seal that shows promise of meeting these demands will be addressed. A high temperature seal test fixture was designed and fabricated to measure static seal leakage performance under engine simulated conditions. Ceramic wafer seal leakage rates are presented for engine-simulated air pressure differentials (up to 100 psi), and temperature (up to 1350 F), sealing both flat and distorted wall conditions, where distortions can be as large as 0.15 inches in only an 18 inch span. Seal leakage rates are low, meeting an industry-established tentative leakage limit for all combinations of temperature, pressure and wall conditions considered. A seal leakage model developed from externally-pressurized gas film bearing theory is also presented. Predicted leakage rates agree favorably with the measured data for nearly all conditions of temperature and pressure. Discrepancies noted at high engine pressure and temperature are attributed to thermally-induced, non-uniform changes in the size and shape of the leakage gap condition. The challenging thermal environment the seal must operate in places considerable demands on the seal concept and material selection. Of the many high temperature materials considered in the design, ceramics were the only materials that met the many challenging seal material design requirements. Of the aluminum oxide, silicon carbide, and silicon nitride ceramics considered in the material ranking scheme developed herein, the silicon nitride class of ceramics ranked the highest because of their high temperature strength; resistance to the intense heating rates; resistance to hydrogen damage; and good structural properties. Baseline seal feasibility has been established through the research conducted in this investigation. Recommendations for future work are also discussed.

Crowding Shifts the FMN Recognition Mechanism of Riboswitch Aptamer from Conformational Selection to Induced Fit.

PubMed

Rode, Ambadas B; Endoh, Tamaki; Sugimoto, Naoki

2018-06-04

In bacteria, the binding between the riboswitch aptamer domain and ligand is regulated by environmental cues, such as low Mg 2+ in macrophages during pathogenesis to ensure spatiotemporal expression of virulence genes. Binding was investigated between the flavin mononucleotide (FMN) riboswitch aptamer and its anionic ligand in the presence of molecular crowding agent without Mg 2+ ion, which mimics pathogenic conditions. Structural, kinetic, and thermodynamic analyses under the crowding revealed more dynamic conformational rearrangements of the FMN riboswitch aptamer compared to dilute Mg 2+ -containing solution. It is hypothesized that under crowding conditions FMN binds through an induced fit mechanism in contrast to the conformational selection mechanism previously demonstrated in dilute Mg 2+ solution. Since these two mechanisms involve different conformational intermediates and rate constants, these findings have practical significance in areas such as drug design and RNA engineering. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Laser engines operating by resonance absorption.

PubMed

Garbuny, M; Pechersky, M J

1976-05-01

The coherence properties and power levels of lasers available at present lend themselves to the remote operation of mechanical engines by resonance absorption in a working gas. Laser radiation is capable of producing extremely high temperatures in a gas. Limits to the achievable temperatures in the working gas of an engine are imposed by the solid walls and by loss of resonance absorption due to thermal saturation, bleaching, and dissociation. However, it is shown that by proper control of the laser beam in space, time, and frequency, as well as by choice of the absorbing gas, these limits are to a great extent removed so that very high temperatures are indeed attainable. The working gas is largely monatomic, preferably helium with the addition of a few volume percent of an absorber. Such a gas mixture, internally heated, permits an optimization of the expansion ratio, with resulting thermal efficiencies and work ratios, not achievable in conventional engines. A relationship between thermal efficiency and work ratio is derived that is quite general for the optimization condition. The performance of laser piston engines, turbines, and the Stirling cycle based on these principles is discussed and compared with conventional engine operation. Finally, a brief discussion is devoted to the possibility and concepts for the direct conversion of selective vibrational or electronic excitation into mechanical work, bypassing the translational degrees of freedom.

Distortions and gender-related differences in the perception of mechanical engineering in high school students.

PubMed

Ferrando Piera, Pere Joan; Gutiérrez-Colón Plana, Mar; Paleo Cageao, Paloma; de la Flor López, Silvia; Ferrando Piera, Francesc

2013-01-01

The reason for this study was the low interest that high school students, particularly females, show for the subject of mechanical engineering (ME). We assumed that this problem was partly due to: (a) lack of understanding of the tasks involved in ME, and (b) a distorted and negative perception of the professional environment and working conditions. To assess these two assumptions, two measurement instruments (tasks and perceptions) were developed and administered in a sample of 496 high school students. A multiple-group design was used and data was analyzed by using an extended item response theory model. In general terms, the results agreed with our expectations. However, no significant gender differences were found. The implications of the results for future improvements are discussed.

United States Air Force Graduate Student Summer Support Program 1986. Program Technical Report. Volume 2

DTIC Science & Technology

1986-12-01

Engineering University of Wisconsin- Madison Mechanics, 1985 Dept. of Engineering Mechanics Specialty: Engineering Mechanics 1415 Johnson Drive Assigned: RPL... Madison , WI 53706 (608) 262-3990 Brian J. Doherty Degree: B.S.E., Bioenginnering, 1984 Duke University Specialty: Bloengineering Biomedical Engineering...Assigned: ML Kent, OH 44242 (216) 672-2246 Gregory L. Walker Degree: B.S., Engineering University of Wisconsin- Madison Mechanics, 1985 Engineering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holland, Steven C.; Artier, Juliana; Miller, Neil T.

Genetic engineering of photosynthetic organisms typically redirects native metabolism towards desirable products, which thereby represent new metabolic sinks. There is limited information on how these modifications impact the evolved mechanisms of photosynthetic energy metabolism and cellular growth. Two engineered strains of Synechocystis sp. PCC 6803 with altered carbon sink capacity were assayed for their photosynthetic and CO 2 concentrating mechanism properties in conditions of high and low inorganic carbon (Ci) availability. In the ΔglgC mutant, glycogen cannot be synthesized and a carbon sink pathway has been effectively removed. The JU547 strain has been engineered by integration of the Pseudomonas syringaemore » ethylene forming enzyme and provides a new sink. When cultured under high carbon conditions, ΔglgC displayed diminished photochemical efficiency, a more reduced NADPH pool, delayed initiation of the Calvin-Benson-Bassham cycle, and impairment of linear and cyclic electron flows. It also exhibited a large decrease in photochemical quenching indicative of the accumulation of Q A-, normally associated with a reduced PQ pool, but appears instead to be the result of an undefined dissipative mechanism to spill excess energy. In the case of carbon sink integration, JU547 displayed slightly more oxidized PQ and NADPH pools and increased rates of cyclic electron flow and an enhanced demand for inorganic carbon as suggested by increase in the expression of the bicarbonate transporter, SbtA. Overall, the results highlight the importance of the native regulatory network of autotrophic metabolism in governing photosynthetic performance and provide cogent examples of both predicable and difficult to predict phenotypic consequences upon installation of new pathways in autotrophs.« less

Engineered in vitro disease models.

PubMed

Benam, Kambez H; Dauth, Stephanie; Hassell, Bryan; Herland, Anna; Jain, Abhishek; Jang, Kyung-Jin; Karalis, Katia; Kim, Hyun Jung; MacQueen, Luke; Mahmoodian, Roza; Musah, Samira; Torisawa, Yu-suke; van der Meer, Andries D; Villenave, Remi; Yadid, Moran; Parker, Kevin K; Ingber, Donald E

2015-01-01

The ultimate goal of most biomedical research is to gain greater insight into mechanisms of human disease or to develop new and improved therapies or diagnostics. Although great advances have been made in terms of developing disease models in animals, such as transgenic mice, many of these models fail to faithfully recapitulate the human condition. In addition, it is difficult to identify critical cellular and molecular contributors to disease or to vary them independently in whole-animal models. This challenge has attracted the interest of engineers, who have begun to collaborate with biologists to leverage recent advances in tissue engineering and microfabrication to develop novel in vitro models of disease. As these models are synthetic systems, specific molecular factors and individual cell types, including parenchymal cells, vascular cells, and immune cells, can be varied independently while simultaneously measuring system-level responses in real time. In this article, we provide some examples of these efforts, including engineered models of diseases of the heart, lung, intestine, liver, kidney, cartilage, skin and vascular, endocrine, musculoskeletal, and nervous systems, as well as models of infectious diseases and cancer. We also describe how engineered in vitro models can be combined with human inducible pluripotent stem cells to enable new insights into a broad variety of disease mechanisms, as well as provide a test bed for screening new therapies.

Effects of service condition on rolling contact fatigue failure mechanism and lifetime of thermal spray coatings—A review

NASA Astrophysics Data System (ADS)

Cui, Huawei; Cui, Xiufang; Wang, Haidou; Xing, Zhiguo; Jin, Guo

2015-01-01

The service condition determines the Rolling Contact Fatigue(RCF) failure mechanism and lifetime under ascertain material structure integrity parameter of thermal spray coating. The available literature on the RCF testing of thermal spray coatings under various condition services is considerable; it is generally difficult to synthesize all of the result to obtain a comprehensive understanding of the parameters which has a great effect on a thermal spray coating's resistance of RCF. The effects of service conditions(lubrication states, contact stresses, revolve speed, and slip ratio) on the changing of thermal spray coatings' contact fatigue lifetime is introduced systematically. The effects of different service condition on RCF failure mechanism of thermal spray coating from the change of material structure integrity are also summarized. Moreover, In order to enhance the RCF performance, the parameter optimal design formula of service condition and material structure integrity is proposed based on the effect of service condition on thermal spray coatings' contact fatigue lifetime and RCF failure mechanism. The shortage of available literature and the forecast focus in future researches are discussed based on available research. The explicit result of RCF lifetime law and parameter optimal design formula in term of lubrication states, contact stresses, revolve speed, and slip ratio, is significant to improve the RCF performance on the engineering application.

Fiber Development and Matrix Production in Tissue Engineered Menisci using Bovine Mesenchymal Stem Cells and Fibrochondrocytes

PubMed Central

McCorry, Mary Clare; Bonassar, Lawrence J.

2017-01-01

Mesenchymal stem cells (MSCs) have been investigated with promising results for meniscus healing and tissue engineering. While MSCs are known to contribute to ECM production, less is known about how MSCs produce and align large organized fibers for application to tissue engineering the meniscus. The goal of this study was to investigate the capability of MSCs to produce and organize extracellular matrix molecules compared to meniscal fibrochondrocytes (FCCs). Bovine FCCs and MSCs were encapsulated in an anatomically accurate collagen meniscus using mono-culture and co-culture of each cell type. Each meniscus was mechanically anchored at the horns to mimic the physiological fixation by the meniscal entheses. Mechanical fixation generates a static mechanical boundary condition previously shown to induce formation of oriented fiber by FCCs. Samples were cultured for 4 weeks and then evaluated for biochemical composition and fiber development. MSCs increased the GAG and collagen production in both co-culture and mono-culture groups compared to FCC mono-culture. Collagen organization was greatest in the FCC mono-culture group. While MSCs had increased matrix production they lacked the fiber organization capabilities of FCCs. This study suggests that GAG production and fiber formation are linked. Co-culture can be used as a means of balancing the synthetic properties of MSCs and the matrix remodeling capabilities of FCCs for tissue engineering applications. PMID:27925474

Design and efficacy of a single-use bioreactor for heart valve tissue engineering.

PubMed

Converse, Gabriel L; Buse, Eric E; Neill, Kari R; McFall, Christopher R; Lewis, Holley N; VeDepo, Mitchell C; Quinn, Rachael W; Hopkins, Richard A

2017-02-01

Heart valve tissue engineering offers the promise of improved treatments for congenital heart disorders; however, widespread clinical availability of a tissue engineered heart valve (TEHV) has been hindered by scientific and regulatory concerns, including the lack of a disposable, bioreactor system for nondestructive valve seeding and mechanical conditioning. Here we report the design for manufacture and the production of full scale, functional prototypes of such a system. To evaluate the efficacy of this bioreactor as a tool for seeding, ovine aortic valves were decellularized and subjected to seeding with human mesenchymal stem cells (hMSC). The effects of pulsatile conditioning using cyclic waveforms tuned to various negative and positive chamber pressures were evaluated, with respect to the seeding of cells on the decellularized leaflet and the infiltration of seeded cells into the interstitium of the leaflet. Infiltration of hMSCs into the aortic valve leaflet was observed following 72 h of conditioning under negative chamber pressure. Additional conditioning under positive pressure improved cellular infiltration, while retaining gene expression within the MSC-valve interstitial cell phenotype lineage. This protocol resulted in a subsurface pilot population of cells, not full tissue recellularization. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 249-259, 2017. © 2015 Wiley Periodicals, Inc.

Computational design of a pH stable enzyme: understanding molecular mechanism of penicillin acylase's adaptation to alkaline conditions.

PubMed

Suplatov, Dmitry; Panin, Nikolay; Kirilin, Evgeny; Shcherbakova, Tatyana; Kudryavtsev, Pavel; Svedas, Vytas

2014-01-01

Protein stability provides advantageous development of novel properties and can be crucial in affording tolerance to mutations that introduce functionally preferential phenotypes. Consequently, understanding the determining factors for protein stability is important for the study of structure-function relationship and design of novel protein functions. Thermal stability has been extensively studied in connection with practical application of biocatalysts. However, little work has been done to explore the mechanism of pH-dependent inactivation. In this study, bioinformatic analysis of the Ntn-hydrolase superfamily was performed to identify functionally important subfamily-specific positions in protein structures. Furthermore, the involvement of these positions in pH-induced inactivation was studied. The conformational mobility of penicillin acylase in Escherichia coli was analyzed through molecular modeling in neutral and alkaline conditions. Two functionally important subfamily-specific residues, Gluβ482 and Aspβ484, were found. Ionization of these residues at alkaline pH promoted the collapse of a buried network of stabilizing interactions that consequently disrupted the functional protein conformation. The subfamily-specific position Aspβ484 was selected as a hotspot for mutation to engineer enzyme variant tolerant to alkaline medium. The corresponding Dβ484N mutant was produced and showed 9-fold increase in stability at alkaline conditions. Bioinformatic analysis of subfamily-specific positions can be further explored to study mechanisms of protein inactivation and to design more stable variants for the engineering of homologous Ntn-hydrolases with improved catalytic properties.

Computational Design of a pH Stable Enzyme: Understanding Molecular Mechanism of Penicillin Acylase's Adaptation to Alkaline Conditions

PubMed Central

Suplatov, Dmitry; Panin, Nikolay; Kirilin, Evgeny; Shcherbakova, Tatyana; Kudryavtsev, Pavel; Švedas, Vytas

2014-01-01

Protein stability provides advantageous development of novel properties and can be crucial in affording tolerance to mutations that introduce functionally preferential phenotypes. Consequently, understanding the determining factors for protein stability is important for the study of structure-function relationship and design of novel protein functions. Thermal stability has been extensively studied in connection with practical application of biocatalysts. However, little work has been done to explore the mechanism of pH-dependent inactivation. In this study, bioinformatic analysis of the Ntn-hydrolase superfamily was performed to identify functionally important subfamily-specific positions in protein structures. Furthermore, the involvement of these positions in pH-induced inactivation was studied. The conformational mobility of penicillin acylase in Escherichia coli was analyzed through molecular modeling in neutral and alkaline conditions. Two functionally important subfamily-specific residues, Gluβ482 and Aspβ484, were found. Ionization of these residues at alkaline pH promoted the collapse of a buried network of stabilizing interactions that consequently disrupted the functional protein conformation. The subfamily-specific position Aspβ484 was selected as a hotspot for mutation to engineer enzyme variant tolerant to alkaline medium. The corresponding Dβ484N mutant was produced and showed 9-fold increase in stability at alkaline conditions. Bioinformatic analysis of subfamily-specific positions can be further explored to study mechanisms of protein inactivation and to design more stable variants for the engineering of homologous Ntn-hydrolases with improved catalytic properties. PMID:24959852

Data Documentation for Navy Civilian Manpower Study,

DTIC Science & Technology

1986-09-01

Engineering 0830 Mechanical Engineer 0840 Nuclear Engineering 0850 Electrical Engineering 0855 Electronics Engineering 0856 Electronics ...OCCUPATIONAL LEVEL (DONOL) CODES DONOL code Title 1060 Engineering Drafting 1061 Electronics Technician w 1062 Engineering Technician 1063 Industrial...Architect 2314 Electrical Engineer 2315 Electronic Engineer 2316 Industrial Engineer 2317 Mechanical Engineer 2318

Effect of hygroscopic treatments and load applications on engineering properties of flakeboards

Treesearch

M.C. Yeh; R.C. Tang; C.Y. Hse

1991-01-01

The study of mechanical properties of hardwood structural flakeboards (white oak, red oak, and sweetgum) as affected by hygroscopic treatments and load applications, individually or collectively, is reported. The shear moduli and moduli of elasticty determined by stress waves (Esw) are drastically reduced by cycle conditions of 65/95/65 percent...

Bioactive Cellulose Nanocrystal Reinforced 3D Printable Poly(epsilon-caprolactone) Nanocomposite for Bone Tissue Engineering

NASA Astrophysics Data System (ADS)

Hong, Jung Ki

Polymeric bone scaffolds are a promising tissue engineering approach for the repair of critical-size bone defects. Porous three-dimensional (3D) scaffolds play an essential role as templates to guide new tissue formation. However, there are critical challenges arising from the poor mechanical properties and low bioactivity of bioresorbable polymers, such as poly(a-caprolactone) (PCL) in bone tissue engineering applications. This research investigates the potential use of cellulose nanocrystals (CNCs) as multi-functional additives that enhance the mechanical properties and increase the biomineralization rate of PCL. To this end, an in vitro biomineralization study of both sulfuric acid hydrolyzed- CNCs (SH-CNCs) and surface oxidized-CNCs (SO-CNCs) has been performed in simulated body fluid in order to evaluate the bioactivity of the surface functional groups, sulfate and carboxyl groups, respectively. PCL nanocomposites were prepared with different SO-CNC contents and the chemical/physical properties of the nanocomposites were analyzed. 3D porous scaffolds with fully interconnected pores and well-controlled pore sizes were fabricated from the PCL nanocomposites with a 3D printer. The mechanical stability of the scaffolds were studied using creep test under dry and submersion conditions. Lastly, the biocompatibility of CNCs and 3D printed porous scaffolds were assessed in vitro.. The carboxyl groups on the surface of SO-CNCs provided a significantly improved calcium ion binding ability which could play an important role in the biomineralization (bioactivity) by induction of mineral formation for bone tissue engineering applications. In addition, the mechanical properties of porous PCL nanocomposite scaffolds were pronouncedly reinforced by incorporation of SO-CNCs. Both the compressive modulus and creep resistance of the PCL scaffolds were enhanced either in dry or in submersion conditions at 37 °C. Lastly, the biocompatibility study demonstrated that both the CNCs and material fabrication processes (e.g., PCL nanocomposites and 3D printing) were not toxic to the preosteoblasts (MC3T3 cells). Also, the SO-CNCs showed a positive effect on biomineralization of PCL scaffolds (i.e., accelerated calcium or mineral deposits on the surface of the scaffolds) during in vitro study. Overall, the SO-CNCs could play a critical role in the development of scaffold materials as a potential candidate for reinforcing nanofillers in bone tissue engineering applications.

Mechanics of Granular Materials (MGM) Investigators

NASA Technical Reports Server (NTRS)

2000-01-01

Key persornel in the Mechanics of Granular Materials (MGM) experiment at the University of Colorado at Boulder include Tawnya Ferbiak (software engineer), Susan Batiste (research assistant), and Christina Winkler (graduate research assistant). Sand and soil grains have faces that can cause friction as they roll and slide against each other, or even cause sticking and form small voids between grains. This complex behavior can cause soil to behave like a liquid under certain conditions such as earthquakes or when powders are handled in industrial processes. MGM experiments aboard the Space Shuttle use the microgravity of space to simulate this behavior under conditions that cannot be achieved in laboratory tests on Earth. MGM is shedding light on the behavior of fine-grain materials under low effective stresses. Applications include earthquake engineering, granular flow technologies (such as powder feed systems for pharmaceuticals and fertilizers), and terrestrial and planetary geology. Nine MGM specimens have flown on two Space Shuttle flights. Another three are scheduled to fly on STS-107. The principal investigator is Stein Sture of the University of Colorado at Boulder. (Credit: University of Colorado at Boulder).

Regulation of EPS production in Lactobacillus casei LC2W through metabolic engineering.

PubMed

Li, N; Huang, Y; Liu, Z; You, C; Guo, B

2015-12-01

Lactobacillus casei LC2W is an exopolysaccharide(EPS)-producing strain with probiotic effects. The low efficiency and unclear regulation mechanism of EPS biosynthesis have become main constraints for its application in food industry. To investigate the major rate-limiting factors of EPS biosynthesis and to improve its yield, metabolic engineering was applied to this strain. Eight relevant genes related to central metabolism, sugar-nucleotides supply, glycosyltransferase and cofactor engineering were cloned and overexpressed. The results suggested that nox, pfk, rfbB and galT genes were the largest contributors to EPS biosynthesis in this study, which elevated EPS yield by 46·0, 20, 17·4 and 19·6% respectively. Notably, under aerobic condition which was not a suitable condition for lactobacilli to grow in, recombinant strain LC-nox achieved the highest EPS yield of 263·7 mg l(-1) , which was increased by 75% compared to that of the starting strain. The oxygen stress was excluded since the phenomenon was not observed in the control strain under the same condition. Therefore, it was probably that higher NADH oxidase activity led to a decreased NADH availability and reduced lactate concentration, which resulted in the elevation of EPS yield. This study contributed to the understanding of EPS biosynthesis in Lact. casei through metabolic engineering and provided a starting point for introducing cofactor engineering into this strain. Overexpression of NADH oxidase was found to have a most significant effect on the EPS production. It is the first report that EPS could be accumulated to such a high level under aerobic condition in lactobacilli. Our results provided a novel strategy for the improvement of EPS production in lactic acid bacteria. © 2015 The Society for Applied Microbiology.

Recent Advances in Composite Damage Mechanics

NASA Technical Reports Server (NTRS)

Reifsnider, Ken; Case, Scott; Iyengar, Nirmal

1996-01-01

The state of the art and recent developments in the field of composite material damage mechanics are reviewed, with emphasis on damage accumulation. The kinetics of damage accumulation are considered with emphasis on the general accumulation of discrete local damage events such as single or multiple fiber fractures or microcrack formation. The issues addressed include: how to define strength in the presence of widely distributed damage, and how to combine mechanical representations in order to predict the damage tolerance and life of engineering components. It is shown that a damage mechanics approach can be related to the thermodynamics of the damage accumulation processes in composite laminates subjected to mechanical loading and environmental conditions over long periods of time.

Re-Educating Jet-Engine-Researchers to Stay Relevant

NASA Astrophysics Data System (ADS)

Gal-Or, Benjamin

2016-06-01

To stay relevantly supported, jet-engine researchers, designers and operators should follow changing uses of small and large jet engines, especially those anticipated to be used by/in the next generation, JET-ENGINE-STEERED ("JES") fleets of jet drones but fewer, JES-Stealth-Fighter/Strike Aircraft. In addition, some diminishing returns from isolated, non-integrating, jet-engine component studies, vs. relevant, supersonic, shock waves control in fluidic-JES-side-effects on compressor stall dynamics within Integrated Propulsion Flight Control ("IPFC"), and/or mechanical JES, constitute key relevant methods that currently move to China, India, South Korea and Japan. The central roles of the jet engine as primary or backup flight controller also constitute key relevant issues, especially under post stall conditions involving induced engine-stress while participating in crash prevention or minimal path-time maneuvers to target. And when proper instructors are absent, self-study of the JES-STVS REVOLUTION is an updating must, where STVS stands for wing-engine-airframe-integrated, embedded stealthy-jet-engine-inlets, restructured engines inside Stealth, Tailless, canard-less, Thrust Vectoring IFPC Systems. Anti-terror and Airliners Super-Flight-Safety are anticipated to overcome US legislation red-tape that obstructs JES-add-on-emergency-kits-use.

Joint measurements of black carbon and particle mass for ...

EPA Pesticide Factsheets

The black carbon (BC) emitted from heavy-duty diesel vehicles(HDDVs) is an important source of urban atmospheric pollution and createsstrong climate-forcing impacts. The emission ratio of BC to totalparticle mass (PM) (i.e., BC/PM ratio) is an essential variable used toestimate total BC emissions from historical PM data; however, theseratios have not been measured using portable emission measurement systems(PEMS) in order to obtain real-world measurements over a wide range ofdriving conditions. In this study, we developed a PEMS platform byintegrating two Aethalometers and an electric low pressure impactor torealize the joint measurement of real-world BC and PM emissions for tenHDDVs in China. Test results showed that the average BC/PM ratio for fiveHDDVs equipped with mechanical fuel injection (MI) engines was 0.43±0.06,significantly lower (P<0.05) than another five HDDVs equipped withelectronically-controlled fuel injection (EI) engines (0.56±0.12).Traffic conditions also affected the BC/PM ratios with higher BC/PMratios on freeway routes than on local roads. Further, higher ratios wereobserved for HDDVs equipped with EI engines than for the MI engines forthe highway and local road routes. With an operating mode binningapproach, we observed that the instantaneous BC/PM ratios of EI enginevehicles were above those of the MI engine vehicles in all operatingmodes except for the braking mode (i.e., Bin 0). Therefore, the compleximpacts from engine technology and

LOX droplet vaporization in a supercritical forced convective environment

NASA Technical Reports Server (NTRS)

Hsiao, Chia-Chun; Yang, Vigor

1993-01-01

Modern liquid rocket engines often use liquid oxygen (LOX) and liquid hydrogen (LH2) as propellants to achieve high performance, with the engine operational conditions in the supercritical regimes of the propellants. Once the propellant exceeds its critical state, it essentially becomes a puff of dense fluid. The entire field becomes a continuous medium, and no distinct interfacial boundary between the liquid and gas exists. Although several studies have been undertaken to investigate the supercritical droplet behavior at quiescent conditions, very little effort has been made to address the fundamental mechanisms associated with LOX droplet vaporization in a supercritical, forced convective environment. The purpose is to establish a theoretical framework within which supercritical droplet dynamics and vaporization can be studied systematically by means of an efficient and robust numerical algorithm.

Engineered skeletal muscle tissue for soft robotics: fabrication strategies, current applications, and future challenges.

PubMed

Duffy, Rebecca M; Feinberg, Adam W

2014-01-01

Skeletal muscle is a scalable actuator system used throughout nature from the millimeter to meter length scales and over a wide range of frequencies and force regimes. This adaptability has spurred interest in using engineered skeletal muscle to power soft robotics devices and in biotechnology and medical applications. However, the challenges to doing this are similar to those facing the tissue engineering and regenerative medicine fields; specifically, how do we translate our understanding of myogenesis in vivo to the engineering of muscle constructs in vitro to achieve functional integration with devices. To do this researchers are developing a number of ways to engineer the cellular microenvironment to guide skeletal muscle tissue formation. This includes understanding the role of substrate stiffness and the mechanical environment, engineering the spatial organization of biochemical and physical cues to guide muscle alignment, and developing bioreactors for mechanical and electrical conditioning. Examples of engineered skeletal muscle that can potentially be used in soft robotics include 2D cantilever-based skeletal muscle actuators and 3D skeletal muscle tissues engineered using scaffolds or directed self-organization. Integration into devices has led to basic muscle-powered devices such as grippers and pumps as well as more sophisticated muscle-powered soft robots that walk and swim. Looking forward, current, and future challenges include identifying the best source of muscle precursor cells to expand and differentiate into myotubes, replacing cardiomyocytes with skeletal muscle tissue as the bio-actuator of choice for soft robots, and vascularization and innervation to enable control and nourishment of larger muscle tissue constructs. © 2013 Wiley Periodicals, Inc.

Systems Design and Experimental Evaluation of a High-Altitude Relight Test Facility

NASA Astrophysics Data System (ADS)

Paxton, Brendan

Novel advances in gas turbine engine combustor technology, led by endeavors into fuel efficiency and demanding environmental regulations, have been fraught with performance and safety concerns. While the majority of low emissions gas turbine engine combustor technology has been necessary for power generation applications, the push for ultra-low NOx combustion in aircraft jet engines has been ever present. Recent state-of-the-art combustor designs notably tackle historic emissions challenges by operating at fuel-lean conditions, which are characterized by an increase in the amount of air flow sent to the primary combustion zone. While beneficial in reducing NOx emissions, the fuel-lean mechanisms that characterize these combustor designs rely heavily upon high-energy and high-velocity air flows to sufficiently mix and atomize fuel droplets, ultimately leading to flame stability concerns during low-power operation. When operating at high-altitude conditions, these issues are further exacerbated by the presence of low ambient air pressures and temperatures, which can lead to engine flame-out situations and hamper engine relight attempts. To aid academic and industrial research ventures into improving the high-altitude lean blow-out and relight performance of modern gas turbine engine combustor technologies, the High-Altitude Relight Test Facility (HARTF) was designed and constructed at the University of Cincinnati (UC) Combustion and Fire Research Laboratory (CFRL). Following its construction, an experimental evaluation of its abilities to facilitate optically-accessible ignition, combustion, and spray testing for gas turbine engine combustor hardware at simulated high-altitude conditions was performed. In its evaluation, performance limit references were established through testing of the HARTF vacuum and cryogenic air-chilling capabilities. These tests were conducted with regard to end-user control---the creation and the maintenance of a realistic high-altitude environment simulation. To evaluate future testing applications, as well as to understand the abilities of the HARTF to accommodate different sizes and configurations of industrial gas turbine engine combustor hardware, ignition testing was conducted at challenging high-altitude windmilling conditions with a linearly-arranged five-swirler array, replicating the implementation of a multi-cup combustor sector.

Materials from Mussel-Inspired Chemistry for Cell and Tissue Engineering Applications.

PubMed

Madhurakkat Perikamana, Sajeesh Kumar; Lee, Jinkyu; Lee, Yu Bin; Shin, Young Min; Lee, Esther J; Mikos, Antonios G; Shin, Heungsoo

2015-09-14

Current advances in biomaterial fabrication techniques have broadened their application in different realms of biomedical engineering, spanning from drug delivery to tissue engineering. The success of biomaterials depends highly on the ability to modulate cell and tissue responses, including cell adhesion, as well as induction of repair and immune processes. Thus, most recent approaches in the field have concentrated on functionalizing biomaterials with different biomolecules intended to evoke cell- and tissue-specific reactions. Marine mussels produce mussel adhesive proteins (MAPs), which help them strongly attach to different surfaces, even under wet conditions in the ocean. Inspired by mussel adhesiveness, scientists discovered that dopamine undergoes self-polymerization at alkaline conditions. This reaction provides a universal coating for metals, polymers, and ceramics, regardless of their chemical and physical properties. Furthermore, this polymerized layer is enriched with catechol groups that enable immobilization of primary amine or thiol-based biomolecules via a simple dipping process. Herein, this review explores the versatile surface modification techniques that have recently been exploited in tissue engineering and summarizes polydopamine polymerization mechanisms, coating process parameters, and effects on substrate properties. A brief discussion of polydopamine-based reactions in the context of engineering various tissue types, including bone, blood vessels, cartilage, nerves, and muscle, is also provided.

Generator voltage stabilisation for series-hybrid electric vehicles.

PubMed

Stewart, P; Gladwin, D; Stewart, J; Cowley, R

2008-04-01

This paper presents a controller for use in speed control of an internal combustion engine for series-hybrid electric vehicle applications. Particular reference is made to the stability of the rectified DC link voltage under load disturbance. In the system under consideration, the primary power source is a four-cylinder normally aspirated gasoline internal combustion engine, which is mechanically coupled to a three-phase permanent magnet AC generator. The generated AC voltage is subsequently rectified to supply a lead-acid battery, and permanent magnet traction motors via three-phase full bridge power electronic inverters. Two complementary performance objectives exist. Firstly to maintain the internal combustion engine at its optimal operating point, and secondly to supply a stable 42 V supply to the traction drive inverters. Achievement of these goals minimises the transient energy storage requirements at the DC link, with a consequent reduction in both weight and cost. These objectives imply constant velocity operation of the internal combustion engine under external load disturbances and changes in both operating conditions and vehicle speed set-points. An electronically operated throttle allows closed loop engine velocity control. System time delays and nonlinearities render closed loop control design extremely problematic. A model-based controller is designed and shown to be effective in controlling the DC link voltage, resulting in the well-conditioned operation of the hybrid vehicle.

Practical internal combustion engine laser spark plug development

NASA Astrophysics Data System (ADS)

Myers, Michael J.; Myers, John D.; Guo, Baoping; Yang, Chengxin; Hardy, Christopher R.

2007-09-01

Fundamental studies on laser ignition have been performed by the US Department of Energy under ARES (Advanced Reciprocating Engines Systems) and by the California Energy Commission under ARICE (Advanced Reciprocating Internal Combustion Engine). These and other works have reported considerable increases in fuel efficiencies along with substantial reductions in green-house gas emissions when employing laser spark ignition. Practical commercial applications of this technology require low cost high peak power lasers. The lasers must be small, rugged and able to provide stable laser beam output operation under adverse mechanical and environmental conditions. New DPSS (Diode Pumped Solid State) lasers appear to meet these requirements. In this work we provide an evaluation of HESP (High Efficiency Side Pumped) DPSS laser design and performance with regard to its application as a practical laser spark plug for use in internal combustion engines.

Protein Engineering Approaches in the Post-Genomic Era.

PubMed

Singh, Raushan K; Lee, Jung-Kul; Selvaraj, Chandrabose; Singh, Ranjitha; Li, Jinglin; Kim, Sang-Yong; Kalia, Vipin C

2018-01-01

Proteins are one of the most multifaceted macromolecules in living systems. Proteins have evolved to function under physiological conditions and, therefore, are not usually tolerant of harsh experimental and environmental conditions. The growing use of proteins in industrial processes as a greener alternative to chemical catalysts often demands constant innovation to improve their performance. Protein engineering aims to design new proteins or modify the sequence of a protein to create proteins with new or desirable functions. With the emergence of structural and functional genomics, protein engineering has been invigorated in the post-genomic era. The three-dimensional structures of proteins with known functions facilitate protein engineering approaches to design variants with desired properties. There are three major approaches of protein engineering research, namely, directed evolution, rational design, and de novo design. Rational design is an effective method of protein engineering when the threedimensional structure and mechanism of the protein is well known. In contrast, directed evolution does not require extensive information and a three-dimensional structure of the protein of interest. Instead, it involves random mutagenesis and selection to screen enzymes with desired properties. De novo design uses computational protein design algorithms to tailor synthetic proteins by using the three-dimensional structures of natural proteins and their folding rules. The present review highlights and summarizes recent protein engineering approaches, and their challenges and limitations in the post-genomic era. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Characterizing the impact of spatiotemporal variations in stormwater infrastructure on hydrologic conditions

NASA Astrophysics Data System (ADS)

Jovanovic, T.; Mejia, A.; Hale, R. L.; Gironas, J. A.

2015-12-01

Urban stormwater infrastructure design has evolved in time, reflecting changes in stormwater policy and regulations, and in engineering design. This evolution makes urban basins heterogeneous socio-ecological-technological systems. We hypothesize that this heterogeneity creates unique impact trajectories in time and impact hotspots in space within and across cities. To explore this, we develop and implement a network hydro-engineering modeling framework based on high-resolution digital elevation and stormwater infrastructure data. The framework also accounts for climatic, soils, land use, and vegetation conditions in an urban basin, thus making it useful to study the impacts of stormwater infrastructure across cities. Here, to evaluate the framework, we apply it to urban basins in the metropolitan areas of Phoenix, Arizona. We use it to estimate different metrics to characterize the storm-event hydrologic response. We estimate both traditional metrics (e.g., peak flow, time to peak, and runoff volume) as well as new metrics (e.g., basin-scale dispersion mechanisms). We also use the dispersion mechanisms to assess the scaling characteristics of urban basins. Ultimately, we find that the proposed framework can be used to understand and characterize the impacts associated with stormwater infrastructure on hydrologic conditions within a basin. Additionally, we find that the scaling approach helps in synthesizing information but it requires further validation using additional urban basins.

Induction of ICAM-1 Expression in Mouse Embryonic Fibroblasts Cultured on Fibroin-Gelatin Scaffolds

PubMed Central

Nosenko, M. A.; Maluchenko, N. V.; Drutskaya, M. S.; Arkhipova, A. Y.; Agapov, I. I.; Nedospasov, S. A.; Moisenovich, M. M.

2017-01-01

Culturing of allogeneic or autologous cells in three-dimensional bioresorbable scaffolds is an important step in the engineering of constructs for regenerative medicine, as well as for experimental systems to study the mechanisms of cell differentiation and cell-to-cell interaction. Artificial substrates can modulate the phenotype and functional activity of immobilized cells. Investigating these changes is important for understanding the fundamental processes underlying cellular interactions in a 3D microenvironment and for improving tissue-engineered structures. In this study, we investigated the expression of the ICAM-1 adhesion molecule in mouse embryonic fibroblasts (MEF) when cultured on gelatin-fibroin scaffolds. Increased expression of ICAM-1 in MEF was detected only under 3D culture conditions both at the mRNA and protein levels. At the same time, the MEF cultured on various substrates did not oerexpress MAdCAM-1, indicating the selective effect of 3D culture conditions on ICAM-1 expression. One possible mechanism for ICAM-1 induction in MEF is associated with the activation of AP-1, since expression of c-Fos and Junb (but not cJun and Jund) was increased in MEF in 3D. When cultured under 2D conditions, the expression level of AP-1 components did not change. PMID:29104780

Hybrid, experimental and computational, investigation of mechanical components

NASA Astrophysics Data System (ADS)

Furlong, Cosme; Pryputniewicz, Ryszard J.

1996-07-01

Computational and experimental methodologies have unique features for the analysis and solution of a wide variety of engineering problems. Computations provide results that depend on selection of input parameters such as geometry, material constants, and boundary conditions which, for correct modeling purposes, have to be appropriately chosen. In addition, it is relatively easy to modify the input parameters in order to computationally investigate different conditions. Experiments provide solutions which characterize the actual behavior of the object of interest subjected to specific operating conditions. However, it is impractical to experimentally perform parametric investigations. This paper discusses the use of a hybrid, computational and experimental, approach for study and optimization of mechanical components. Computational techniques are used for modeling the behavior of the object of interest while it is experimentally tested using noninvasive optical techniques. Comparisons are performed through a fringe predictor program used to facilitate the correlation between both techniques. In addition, experimentally obtained quantitative information, such as displacements and shape, can be applied in the computational model in order to improve this correlation. The result is a validated computational model that can be used for performing quantitative analyses and structural optimization. Practical application of the hybrid approach is illustrated with a representative example which demonstrates the viability of the approach as an engineering tool for structural analysis and optimization.

Numerical study on the combustion characteristics of a fuel-centered pintle injector for methane rocket engines

NASA Astrophysics Data System (ADS)

Son, Min; Radhakrishnan, Kanmaniraja; Yoon, Youngbin; Koo, Jaye

2017-06-01

A pintle injector is a movable injector capable of controlling injection area and velocities. Although pintle injectors are not a new concept, they have become more notable due to new applications such as planet landers and low-cost engines. However, there has been little consistent research on pintle injectors because they have many design variations and mechanisms. In particular, simulation studies are required for bipropellant applications. In this study, combustion simulation was conducted using methane and oxygen to determine the effects of injection condition and geometries upon combustion characteristics. Steady and two-dimensional axisymmetric conditions were assumed and a 6-step Jones-Lindstedt mechanism with an eddy-dissipation concept model was used for turbulent kinetic reaction. As a result, the results with wide flame angles showed good combustion performances with a large recirculation under the pintle tip. Under lower mass flow-rate conditions, the combustion performance got worse with lower flame angles. To solve this problem, decreasing the pintle opening distance was very effective and the flame angle recovered. In addition, a specific recirculation zone was observed near the post, suggesting that proper design of the post could increase the combustion performance, while the geometry without a recirculation zone had the poor performance.

Construction of combustion models for rapeseed methyl ester bio-diesel fuel for internal combustion engine applications.

PubMed

Golovitchev, Valeri I; Yang, Junfeng

2009-01-01

Bio-diesel fuels are non-petroleum-based diesel fuels consisting of long chain alkyl esters produced by the transesterification of vegetable oils, that are intended for use (neat or blended with conventional fuels) in unmodified diesel engines. There have been few reports of studies proposing theoretical models for bio-diesel combustion simulations. In this study, we developed combustion models based on ones developed previously. We compiled the liquid fuel properties, and the existing detailed mechanism of methyl butanoate ester (MB, C(5)H(10)O(2)) oxidation was supplemented by sub-mechanisms for two proposed fuel constituent components, C(7)H(16) and C(7)H(8)O (and then, by mp2d, C(4)H(6)O(2) and propyne, C(3)H(4)) to represent the combustion model for rapeseed methyl ester described by the chemical formula, C(19)H(34)O(2) (or C(19)H(36)O(2)). The main fuel vapor thermal properties were taken as those of methyl palmitate C(19)H(36)O(2) in the NASA polynomial form of the Burcat database. The special global reaction was introduced to "crack" the main fuel into its constituent components. This general reaction included 309 species and 1472 reactions, including soot and NO(x) formation processes. The detailed combustion mechanism was validated using shock-tube ignition-delay data under diesel engine conditions. For constant volume and diesel engine (Volvo D12C) combustion modeling, this mechanism could be reduced to 88 species participating in 363 reactions.

Altering the swelling pressures within in vitro engineered cartilage is predicted to modulate the configuration of the collagen network and hence improve tissue mechanical properties.

PubMed

Nagel, Thomas; Kelly, Daniel J

2013-06-01

Prestress in the collagen network has a significant impact on the material properties of cartilaginous tissues. It is closely related to the recruitment configuration of the collagen network which defines the transition from lax collagen fibres to uncrimped, load-bearing collagen fibres. This recruitment configuration can change in response to alterations in the external environmental conditions. In this study, the influence of changes in external salt concentration or sequential proteoglycan digestion on the configuration of the collagen network of tissue engineered cartilage is investigated using a previously developed computational model. Collagen synthesis and network assembly are assumed to occur in the tissue configuration present during in vitro culture. The model assumes that if this configuration is more compact due to changes in tissue swelling, the collagen network will adapt by lowering its recruitment stretch. When returned to normal physiological conditions, these tissues will then have a higher prestress in the collagen network. Based on these assumptions, the model demonstrates that proteoglycan digestion at discrete time points during culture as well as culture in a hypertonic medium can improve the functionality of tissue engineered cartilage, while culture in hypotonic solution is detrimental to the apparent mechanical properties of the graft. Copyright © 2013 Elsevier Ltd. All rights reserved.

Development of Photocrosslinkable Urethane-Doped Polyester Elastomers for Soft Tissue Engineering

PubMed Central

Zhang, Yi; Tran, Richard T.; Gyawali, Dipendra; Yang, Jian

2012-01-01

Finding an ideal biomaterial with the proper mechanical properties and biocompatibility has been of intense focus in the field of soft tissue engineering. This paper reports on the synthesis and characterization of a novel crosslinked urethane-doped polyester elastomer (CUPOMC), which was synthesized by reacting a previously developed photocrosslinkable poly (octamethylene maleate citrate) (POMC) prepolymers (pre-POMC) with 1,6-hexamethylene diisocyanate (HDI) followed by thermo- or photo-crosslinking polymerization. The mechanical properties of the CUPOMCs can be tuned by controlling the molar ratios of pre-POMC monomers, and the ratio between the prepolymer and HDI. CUPOMCs can be crosslinked into a 3D network through polycondensation or free radical polymerization reactions. The tensile strength and elongation at break of CUPOMC synthesized under the known conditions range from 0.73±0.12MPa to 10.91±0.64MPa and from 72.91±9.09% to 300.41±21.99% respectively. Preliminary biocompatibility tests demonstrated that CUPOMCs support cell adhesion and proliferation. Unlike the pre-polymers of other crosslinked elastomers, CUPOMC pre-polymers possess great processability demonstrated by scaffold fabrication via a thermally induced phase separation method. The dual crosslinking methods for CUPOMC pre-polymers should enhance the versatile processability of the CUPOMC used in various conditions. Development of CUPOMC should expand the choices of available biodegradable elastomers for various biomedical applications such as soft tissue engineering. PMID:23565318

Towards the production of salt-tolerant crops.

PubMed

Barkla, B J; Vera-Estrella, R; Pantoja, O

1999-01-01

Crop production is affected by numerous environmental factors, with soil salinity and drought having the most detrimental effects. Attempts to improve yield under stress conditions by plant breeding have been unsuccessful, primarily due to the multigenic origin of the adaptive responses. The transfer of genes through genetic engineering of crop plants appears more feasible. Important adaptive mechanisms targeted for potential gene transfer would be the tonoplast Na+/H+ antiport, compatible solute synthesis and, regulation of water channel activity and expression, mechanisms involved in cellular osmoregulation. In this review we discuss recent advances in our understanding of these adaptive mechanisms.

PNIPAAm-based biohybrid injectable hydrogel for cardiac tissue engineering.

PubMed

Navaei, Ali; Truong, Danh; Heffernan, John; Cutts, Josh; Brafman, David; Sirianni, Rachael W; Vernon, Brent; Nikkhah, Mehdi

2016-03-01

Injectable biomaterials offer a non-invasive approach to deliver cells into the myocardial infarct region to maintain a high level of cell retention and viability and initiate the regeneration process. However, previously developed injectable matrices often suffer from low bioactivity or poor mechanical properties. To address this need, we introduced a biohybrid temperature-responsive poly(N-isopropylacrylamide) PNIPAAm-Gelatin-based injectable hydrogel with excellent bioactivity as well as mechanical robustness for cardiac tissue engineering. A unique feature of our work was that we performed extensive in vitro biological analyses to assess the functionalities of cardiomyocytes (CMs) alone and in co-culture with cardiac fibroblasts (CFs) (2:1 ratio) within the hydrogel matrix. The synthesized hydrogel exhibited viscoelastic behavior (storage modulus: 1260 Pa) and necessary water content (75%) to properly accommodate the cardiac cells. The encapsulated cells demonstrated a high level of cell survival (90% for co-culture condition, day 7) and spreading throughout the hydrogel matrix in both culture conditions. A dense network of stained F-actin fibers (∼ 6 × 10(4) μm(2) area coverage, co-culture condition) illustrated the formation of an intact and three dimensional (3D) cell-embedded matrix. Furthermore, immunostaining and gene expression analyses revealed mature phenotypic characteristics of cardiac cells. Notably, the co-culture group exhibited superior structural organization and cell-cell coupling, as well as beating behavior (average ∼ 45 beats per min, co-culture condition, day 7). The outcome of this study is envisioned to open a new avenue for extensive in vitro characterization of injectable matrices embedded with 3D mono- and co-culture of cardiac cells prior to in vivo experiments. In this work, we synthesized a new class of biohybrid temperature-responsive poly(N-isopropylacrylamide) PNIPAAm-Gelatin-based injectable hydrogel with suitable bioactivity and mechanical properties for cardiac tissue engineering. A significant aspect of our work was that we performed extensive in vitro biological analyses to assess the functionality of cardiomyocytes alone and in co-culture with cardiac fibroblasts encapsulated within the 3D hydrogel matrix. Copyright © 2015 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

Standardized Curriculum for Diesel Engine Mechanics.

ERIC Educational Resources Information Center

Mississippi State Dept. of Education, Jackson. Office of Vocational, Technical and Adult Education.

Standardized curricula are provided for two courses for the secondary vocational education program in Mississippi: diesel engine mechanics I and II. The eight units in diesel engine mechanics I are as follows: orientation; shop safety; basic shop tools; fasteners; measurement; engine operating principles; engine components; and basic auxiliary…

Mechanical Engineering Senior Design Project Final Presentations | College

Science.gov Websites

Mechanical Engineering Senior Design Project Final Presentations December 7, 2015 Mechanical Engineering On Wednesday, Dec. 9th, the mechanical engineering senior design project final presentations will be made in and Steven Keller Objective: Design a temperature controlled unit that would cool and maintain a

Ramin Faramarzi | NREL

Science.gov Websites

Ramin Faramarzi Photo of Ramin Faramarzi Ramin Faramarzi Researcher V-Mechanical Engineering Engineering, California State University B.S. Mechanical Engineering, North Carolina State University articles and is a registered mechanical engineer in the state of California. Education M.S. Mechanical

Expose Mechanical Engineering Students to Biomechanics Topics

ERIC Educational Resources Information Center

Shen, Hui

2011-01-01

To adapt the focus of engineering education to emerging new industries and technologies nationwide and in the local area, a biomechanics module has been developed and incorporated into a mechanical engineering technical elective course to expose mechanical engineering students at ONU (Ohio Northern University) to the biomedical engineering topics.…

46 CFR 113.35-9 - Mechanical engine order telegraph systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Mechanical engine order telegraph systems. 113.35-9 Section 113.35-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-9 Mechanical engine order...

46 CFR 113.35-13 - Mechanical engine order telegraph systems; operation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Mechanical engine order telegraph systems; operation...) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-13 Mechanical engine order telegraph systems; operation. If more than one transmitter operates a...

46 CFR 113.35-9 - Mechanical engine order telegraph systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Mechanical engine order telegraph systems. 113.35-9 Section 113.35-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-9 Mechanical engine order...

46 CFR 113.35-13 - Mechanical engine order telegraph systems; operation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Mechanical engine order telegraph systems; operation...) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-13 Mechanical engine order telegraph systems; operation. If more than one transmitter operates a...

46 CFR 113.35-13 - Mechanical engine order telegraph systems; operation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Mechanical engine order telegraph systems; operation...) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-13 Mechanical engine order telegraph systems; operation. If more than one transmitter operates a...

46 CFR 113.35-9 - Mechanical engine order telegraph systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Mechanical engine order telegraph systems. 113.35-9 Section 113.35-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-9 Mechanical engine order...

46 CFR 113.35-13 - Mechanical engine order telegraph systems; operation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Mechanical engine order telegraph systems; operation...) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-13 Mechanical engine order telegraph systems; operation. If more than one transmitter operates a...

46 CFR 113.35-9 - Mechanical engine order telegraph systems.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Mechanical engine order telegraph systems. 113.35-9 Section 113.35-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-9 Mechanical engine order...

Combined Thermomechanical and Environmental Durability of Environmental Barrier Coating Systems on SiC/SiC Ceramic Matrix Composites

NASA Technical Reports Server (NTRS)

Zhu, Dongming; Harder, Bryan; Bhatt, Ramakrishna

2016-01-01

Environmental barrier coatings (EBCs) and SiC/SiC ceramic matrix composites (CMCs) will play a crucial role in next generation turbine engines for hot-section component applications. The development of prime-reliant environmental barrier coatings is essential to the EBC-CMC system durability, ensuring the successful implementations of the high temperature and lightweight engine component technologies for engine applications.This paper will emphasize recent NASA environmental barrier coating and CMC developments for SiC/SiC turbine airfoil components, utilizing advanced coating compositions and processing methods. The emphasis has been particularly placed on thermomechanical and environment durability evaluations of EBC-CMC systems. We have also addressed the integration of the EBCs with advanced SiC/SiC CMCs, and studied the effects of combustion environments and Calcium-Magnesium-Alumino-Silicate (CMAS) deposits on the durability of the EBC-CMC systems under thermal gradient and mechanical loading conditions. Advanced environmental barrier coating systems, including multicomponent rare earth silicate EBCs and HfO2-Si based bond coats, will be discussed for the performance improvements to achieve better temperature capability and CMAS resistance for future engine operating conditions.

Lifing of Engine Components

NASA Technical Reports Server (NTRS)

2005-01-01

The successful development of advanced aerospace engines depends greatly on the capabilities of high performance materials and structures. Advanced materials, such as nickel based single crystal alloys, metal foam, advanced copper alloys, and ceramics matrix composites, have been engineered to provide higher engine temperature and stress capabilities. Thermal barrier coatings have been developed to improve component durability and fuel efficiency, by reducing the substrate hot wall metal temperature and protecting against oxidation and blanching. However, these coatings are prone to oxidation and delamination failures. In order to implement the use of these materials in advanced engines, it is necessary to understand and model the evolution of damage of the metal substrate as well as the coating under actual engine conditions. The models and the understanding of material behavior are utilized in the development of a life prediction methodology for hot section components. The research activities were focused on determining the stress and strain fields in an engine environment under combined thermo-mechanical loads to develop life prediction methodologies consistent with the observed damage formation of the coating and the substrates.

Constructing wetlands: measuring and modeling feedbacks of oxidation processes between plants and clay-rich material

NASA Astrophysics Data System (ADS)

Saaltink, Rémon; Dekker, Stefan C.; Griffioen, Jasper; Wassen, Martin J.

2016-04-01

Interest is growing in using soft sediment as a building material in eco-engineering projects. Wetland construction in the Dutch lake Markermeer is an example: here the option of dredging some of the clay-rich lake-bed sediment and using it to construct 10.000 ha of wetland will soon go under construction. Natural processes will be utilized during and after construction to accelerate ecosystem development. Knowing that plants can eco-engineer their environment via positive or negative biogeochemical plant-soil feedbacks, we conducted a six-month greenhouse experiment to identify the key biogeochemical processes in the mud when Phragmites australis is used as an eco-engineering species. We applied inverse biogeochemical modeling to link observed changes in pore water composition to biogeochemical processes. Two months after transplantation we observed reduced plant growth and shriveling as well as yellowing of foliage. The N:P ratios of plant tissue were low and were affected not by hampered uptake of N but by enhanced uptake of P. Plant analyses revealed high Fe concentrations in the leaves and roots. Sulfate concentrations rose drastically in our experiment due to pyrite oxidation; as reduction of sulfate will decouple Fe-P in reducing conditions, we argue that plant-induced iron toxicity hampered plant growth, forming a negative feedback loop, while simultaneously there was a positive feedback loop, as iron toxicity promotes P mobilization as a result of reduced conditions through root death, thereby stimulating plant growth and regeneration. Given these two feedback mechanisms, we propose that when building wetlands from these mud deposits Fe-tolerant species are used rather than species that thrive in N-limited conditions. The results presented in this study demonstrate the importance of studying the biogeochemical properties of the building material and the feedback mechanisms between plant and soil prior to finalizing the design of the eco-engineering project.

Modeling and Simulation of a Free-Piston Engine with Electrical Generator Using HCCI Combustion

NASA Astrophysics Data System (ADS)

Alrbai, Mohammad

Free-piston engines have the potential to challenge the conventional crankshaft engines by their design simplicity and higher operational efficiency. Many studies have been performed to overcome the limitations of the free-piston devices especially the stability and control issues. The investigations within the presented dissertation aim to satisfy many objectives by employing the approach of chemical kinetics to present the combustion process in the free-piston engine. This approach in addition to its advanced accuracy over the empirical methods, it has many other features like the ability to analyze the engine emissions. The effect of the heat release rate (HRR) on the engine performance is considered as the main objective. Understanding the relation between the HRR and the piston dynamics helps in enhancing the system efficiency and identifying the parameters that affect the overall performance. The dissertation covers some other objectives that belongs to the combustion phasing. Exhaust gas recirculation (EGR), equivalence ratio and the intake temperature represent the main combustion parameters, which have been discussed in this dissertation. To obtain the stability in system performance, the model requires a proper controller to simulate the operation and manage the different system parameters; for this purpose, different controlling techniques have been employed. In addition, the dissertation considers some other topics like engine emissions, fuels and fuels mechanisms. The model of the study describes the processes within a single cylinder, two stroke engine, which includes springs to support higher frequencies, reduce cyclic variations and sustain the engine compression ratio. An electrical generator presents the engine load; the generator supports different load profiles and play the key role in controlling the system. The 1st law of thermodynamics and Newton's 2nd law are applied to couple the piston dynamics with the engine thermodynamics. The model governing equations represent a single zone perfectly stirred reactor (PSR) which contain a perfect mixing ideal gas mixture. The chemical kinetics approach is applied using Cantera/ MATLABRTM toolbox, which presents the combustion process. In this research, a homogenous charge compression ignition (HCCI) at different operational conditions is used. HCCI engines have high efficiencies and low emissions and can work within a wide range of fuels. The results have been presented in a multi-cycle simulation and a parametric study forms. In the case of the multi-cycle simulation, a 100 cycles of the engine operation have been simulated. The overall work that is delivered to the electrical generator presents 47% of the total fuel energy. The model indicates an average frequency of 125 Hz along the operational cycles. In order to eliminate the cyclic variations and ensure a continuous operation, a proportional derivative (PD) controller has been employed. The controller adjusts the generator load in order to minimize the difference between the bottom dead center (BDC) locations along the operation cycles. The PD controller shows weakness in achieving the full steady state operation, for this purpose; a proportional integral (PI) controller has been implemented. The PI controller seeks to achieve a specific compression ratio. The results show that; the PI controller indicates unique behavior after 15 cycles of operation where the model ended to fluctuate between two compression ratios only. The complex relation between the thermodynamics and the dynamics of the engine is the greatest challenge in examining the effectiveness of the PI controller. In the parametric investigations, EGR examinations show that NOx emission is reduced to less than the half, as 30 % of EGR is used; this occurs due to the EGR thermal and dilution effects, which cause significant drop in the peak bulk temperature and CO emissions as well. Under the applied conditions, EGR has the ability to raise the work output ratio by increasing the engine compression ratio. The examination of the EGR temperature on the engine performance indicates that cooled EGR charges have the advantage over the hot EGR mixtures on enhancing the work output ratio. At the same time, EGR temperature affects the NOx formation by speeding its instantaneous reactions rate. The dissertation includes a study of the effect of the intake temperature and the equivalence ratio (φ) as well. The increasing in the intake temperature reduce the time needed for ignition, but leads to a reduction in the work output ratio at the same time. Such results can help in studying high knock resistance fuels where ignition delay is a matter. In the case of the equivalence ratio, lean mixtures show efficiencies that exceed 50% compared to those at the stoichiometric conditions. In the case of the ultra-lean (φ<0.5) combustion, the results show that the NOx emission is with the minimal levels as well as the CO and the unburned hydrocarbons (UHC) emissions. Sensitivity analysis to the chemical kinetic mechanism for the fuel combustion has been presented also in the dissertation. Many mechanisms for different fuels have been investigated, for example; a modified mechanism for Methane that includes 36 species and 222 reactions has been compared with the full GRI 3.0 mechanism (53 species and 325 reactions). The results of this comparison indicate that the modified mechanism has the potential to replace the full one in some cases like in demonstrating the engine operation, but not in the engine emissions analysis.

Mechanical cues in orofacial tissue engineering and regenerative medicine.

PubMed

Brouwer, Katrien M; Lundvig, Ditte M S; Middelkoop, Esther; Wagener, Frank A D T G; Von den Hoff, Johannes W

2015-01-01

Cleft lip and palate patients suffer from functional, aesthetical, and psychosocial problems due to suboptimal regeneration of skin, mucosa, and skeletal muscle after restorative cleft surgery. The field of tissue engineering and regenerative medicine (TE/RM) aims to restore the normal physiology of tissues and organs in conditions such as birth defects or after injury. A crucial factor in cell differentiation, tissue formation, and tissue function is mechanical strain. Regardless of this, mechanical cues are not yet widely used in TE/RM. The effects of mechanical stimulation on cells are not straight-forward in vitro as cellular responses may differ with cell type and loading regime, complicating the translation to a therapeutic protocol. We here give an overview of the different types of mechanical strain that act on cells and tissues and discuss the effects on muscle, and skin and mucosa. We conclude that presently, sufficient knowledge is lacking to reproducibly implement external mechanical loading in TE/RM approaches. Mechanical cues can be applied in TE/RM by fine-tuning the stiffness and architecture of the constructs to guide the differentiation of the seeded cells or the invading surrounding cells. This may already improve the treatment of orofacial clefts and other disorders affecting soft tissues. © 2015 by the Wound Healing Society.

Activities report of the Department of Engineering

NASA Astrophysics Data System (ADS)

Acoustics, aerodynamics, fluid mechanics, design, electrical, materials science, mechanical, control, robotics, soil mechanics, structural engineering, thermodynamics, and turbomachine engineering research are described.

Evaluation of structural and mechanical properties of electrospun nano-micro hybrid of poly hydroxybutyrate-chitosan/silk scaffold for cartilage tissue engineering

PubMed Central

Karbasi, Saeed; Fekrat, Farnoosh; Semnani, Daryoush; Razavi, Shahnaz; Zargar, Elham Naghash

2016-01-01

Background: One of the new methods of scaffold fabrication is a nano-micro hybrid structure in which the properties of the scaffold are improved by introducing nanometer and micrometer structures. This method could be suitable for scaffold designing if some features improve. Materials and Methods: In this study, electrospun nanofibers of 9% weight solution of poly (3-hydroxybutyrate) (P3HB) and a 15% weight of chitosan by trifluoroacetic acid were coated on both the surface of a silk knitted substrate in the optimum condition to improve the mechanical properties of scaffolds for cartilage tissue engineering application. These hybrid nano-micro fibrous scaffolds were characterized by structural and mechanical evaluation methods. Results: Scanning electron microscopy values and porosity analysis showed that average diameter of nanofibers was 584.94 nm in electrospinning part and general porosity was more than 80%. Fourier transform infrared spectroscopy results indicated the presence of all elements without pollution. The tensile test also stated that by electrospinning, as well as adding chitosan, both maximum strength and maximum elongation increased to 187 N and 10 mm. It means that the microfibrous part of scaffold could affect mechanical properties of nano part of the hybrid scaffold, significantly. Conclusions: It could be concluded that P3HB-chitosan/silk hybrid scaffolds can be a good candidate for cartilage tissue engineering. PMID:28028520

Evaluation of structural and mechanical properties of electrospun nano-micro hybrid of poly hydroxybutyrate-chitosan/silk scaffold for cartilage tissue engineering.

PubMed

Karbasi, Saeed; Fekrat, Farnoosh; Semnani, Daryoush; Razavi, Shahnaz; Zargar, Elham Naghash

2016-01-01

One of the new methods of scaffold fabrication is a nano-micro hybrid structure in which the properties of the scaffold are improved by introducing nanometer and micrometer structures. This method could be suitable for scaffold designing if some features improve. In this study, electrospun nanofibers of 9% weight solution of poly (3-hydroxybutyrate) (P3HB) and a 15% weight of chitosan by trifluoroacetic acid were coated on both the surface of a silk knitted substrate in the optimum condition to improve the mechanical properties of scaffolds for cartilage tissue engineering application. These hybrid nano-micro fibrous scaffolds were characterized by structural and mechanical evaluation methods. Scanning electron microscopy values and porosity analysis showed that average diameter of nanofibers was 584.94 nm in electrospinning part and general porosity was more than 80%. Fourier transform infrared spectroscopy results indicated the presence of all elements without pollution. The tensile test also stated that by electrospinning, as well as adding chitosan, both maximum strength and maximum elongation increased to 187 N and 10 mm. It means that the microfibrous part of scaffold could affect mechanical properties of nano part of the hybrid scaffold, significantly. It could be concluded that P3HB-chitosan/silk hybrid scaffolds can be a good candidate for cartilage tissue engineering.

The Educational Needs of Graduate Mechanical Engineers in New Zealand.

ERIC Educational Resources Information Center

Deans, J.

1999-01-01

Surveys graduate and undergraduate mechanical engineering students at the University of Auckland. Shows that the dominant work activities of New Zealand mechanical engineers include design and consultancy and that graduate engineers rapidly migrate into management. (Author/CCM)

Analysis of oil consumption in cylinder of diesel engine for optimization of piston rings

NASA Astrophysics Data System (ADS)

Zhang, Junhong; Zhang, Guichang; He, Zhenpeng; Lin, Jiewei; Liu, Hai

2013-01-01

The performance and particulate emission of a diesel engine are affected by the consumption of lubricating oil. Most studies on oil consumption mechanism of the cylinder have been done by using the experimental method, however they are very costly. Therefore, it is very necessary to study oil consumption mechanism of the cylinder and obtain the accurate results by the calculation method. Firstly, four main modes of lubricating oil consumption in cylinder are analyzed and then the oil consumption rate under common working conditions are calculated for the four modes based on an engine. Then, the factors that affect the lubricating oil consumption such as working conditions, the second ring closed gap, the elastic force of the piston rings are also investigated for the four modes. The calculation results show that most of the lubricating oil is consumed by evaporation on the liner surface. Besides, there are three other findings: (1) The oil evaporation from the liner is determined by the working condition of an engine; (2) The increase of the ring closed gap reduces the oil blow through the top ring end gap but increases blow-by; (3) With the increase of the elastic force of the ring, both the left oil film thickness and the oil throw-off at the top ring decrease. The oil scraping of the piston top edge is consequently reduced while the friction loss between the rings and the liner increases. A neural network prediction model of the lubricating oil consumption in cylinder is established based on the BP neural network theory, and then the model is trained and validated. The main piston rings parameters which affect the oil consumption are optimized by using the BP neural network prediction model and the prediction accuracy of this BP neural network is within 8%, which is acceptable for normal engineering applications. The oil consumption is also measured experimentally. The relative errors of the calculated and experimental values are less than 10%, verifying the validity of the simulation results. Applying the established simulation model and the validated BP network model is able to generate numerical results with sufficient accuracy, which significantly reduces experimental work and provides guidance for the optimal design of the piston rings diesel engines.

Coupling of Mechanical Behavior of Cell Components to Electrochemical-Thermal Models for Computer-Aided Engineering of Batteries under Abuse (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pesaran, A.; Wierzbicki, T.; Sahraei, E.

The EV Everywhere Grand Challenge aims to produce plug-in electric vehicles as affordable and convenient for the American family as gasoline-powered vehicles by 2022. Among the requirements set by the challenge, electric vehicles must be as safe as conventional vehicles, and EV batteries must not lead to unsafe situations under abuse conditions. NREL's project started in October 2013, based on a proposal in response to the January 2013 DOE VTO FOA, with the goal of developing computer aided engineering tools to accelerate the development of safer lithium ion batteries.

Simulations of Instabilities in Complex Valve and Feed Systems

NASA Technical Reports Server (NTRS)

Ahuja, Vineet; Hosangadi, Ashvin; Shipman, Jeremy; Cavallo, Peter A.

2006-01-01

CFD analyses are playing an increasingly important role in identifying and characterizing flow induced instabilities in rocket engine test facilities and flight systems. In this paper, we analyze instability mechanisms that range from turbulent pressure fluctuations due to vortex shedding in structurally complex valve systems to flow resonance in plug cavities to large scale pressure fluctuations due to collapse of cavitation induced vapor clouds. Furthermore, we discuss simulations of transient behavior related to valve motion that can serve as guidelines for valve scheduling. Such predictions of valve response to varying flow conditions is of crucial importance to engine operation and testing.

Simulations of NOx Emissions from Low Emissions Discrete Jet Injector Combustor Tests

NASA Technical Reports Server (NTRS)

Ajmani, Kumud; Breisacher, Kevin

2014-01-01

An experimental and computational study was conducted to evaluate the performance and emissions characteristics of a candidate Lean Direct Injection (LDI) combustor configuration with a mix of simplex and airblast injectors. The National Combustion Code (NCC) was used to predict the experimentally measured EINOx emissions for test conditions representing low power, medium power, and high-power engine cycle conditions. Of the six cases modeled with the NCC using a reduced-kinetics finite-rate mechanism and lagrangian spray modeling, reasonable predictions of combustor exit temperature and EINOx were obtained at two high-power cycle conditions.

Defining a region of optimization based on engine usage data

DOEpatents

Jiang, Li; Lee, Donghoon; Yilmaz, Hakan; Stefanopoulou, Anna

2015-08-04

Methods and systems for engine control optimization are provided. One or more operating conditions of a vehicle engine are detected. A value for each of a plurality of engine control parameters is determined based on the detected one or more operating conditions of the vehicle engine. A range of the most commonly detected operating conditions of the vehicle engine is identified and a region of optimization is defined based on the range of the most commonly detected operating conditions of the vehicle engine. The engine control optimization routine is initiated when the one or more operating conditions of the vehicle engine are within the defined region of optimization.

Generation, Analysis and Characterization of Anisotropic Engineered Meta Materials

NASA Astrophysics Data System (ADS)

Trifale, Ninad T.

A methodology for a systematic generation of highly anisotropic micro-lattice structures was investigated. Multiple algorithms for generation and validation of engineered structures are developed and evaluated. Set of all possible permutations of structures for an 8-node cubic unit cell were considered and the degree of anisotropy of meta-properties in heat transport and mechanical elasticity were evaluated. Feasibility checks were performed to ensure that the generated unit cell network was repeatable and a continuous lattice structure. Four different strategies for generating permutations of the structures are discussed. Analytical models were developed to predict effective thermal, mechanical and permeability characteristics of these cellular structures.Experimentation and numerical modeling techniques were used to validate the models that are developed. A self-consistent mechanical elasticity model was developed which connects the meso-scale properties to stiffness of individual struts. A three dimensional thermal resistance network analogy was used to evaluate the effective thermal conductivity of the structures. The struts were modeled as a network of one dimensional thermal resistive elements and effective conductivity evaluated. Models were validated against numerical simulations and experimental measurements on 3D printed samples. Model was developed to predict effective permeability of these engineered structures based on Darcy's law. Drag coefficients were evaluated for individual connections in transverse and longitudinal directions and an interaction term was calibrated from the experimental data in literature in order to predict permeability. Generic optimization framework coupled to finite element solver is developed for analyzing any application involving use of porous structures. An objective functions were generated structure to address frequently observed trade-off between the stiffness, thermal conductivity, permeability and porosity. Three application were analyzed for potential use of engineered materials. Heat spreader application involving thermal and mechanical constraints, artificial bone grafts application involving mechanical and permeability constraints and structural materials applications involving mechanical, thermal and porosity constraints is analyzed. Recommendations for optimum topologies for specific operating conditions are provided.

LARGE STRAIN STIMULATION PROMOTES EXTRACELLULAR MATRIX PRODUCTION AND STIFFNESS IN AN ELASTOMERIC SCAFFOLD MODEL

PubMed Central

D’more, Antonio; Soares, Joao; Stella, John A.; Zhang, Will; Amoroso, Nicholas J.; Mayer, John E.; Wagner, William R.; Sacks, Michael S.

2016-01-01

Mechanical conditioning of engineered tissue constructs is widely recognized as one of the most relevant methods to enhance tissue accretion and microstructure, leading to improved mechanical behaviors. The understanding of the underlying mechanisms remains rather limited, restricting the development of in silico models of these phenomena, and the translation of engineered tissues into clinical application. In the present study, we examined the role of large strip-biaxial strains (up to 50%) on ECM synthesis by vascular smooth muscle cells (VSMCs) micro-integrated into electrospun polyester urethane urea (PEUU) constructs over the course of 3 weeks. Experimental results indicated that VSMC biosynthetic behavior was quite sensitive to tissue strain maximum level, and that collagen was the primary ECM component synthesized. Moreover, we found that while a 30% peak strain level achieved maximum ECM synthesis rate, further increases in strain level lead to a reduction in ECM biosynthesis. Subsequent mechanical analysis of the formed collagen fiber network was performed by removing the scaffold mechanical responses using a strain-energy based approach, showing that the de-novo collagen also demonstrated mechanical behaviors substantially better than previously obtained with small strain training and comparable to mature collagenous tissues. We conclude that the application of large deformations can play a critical role not only in the quantity of ECM synthesis (i.e. the rate of mass production), but also on the modulation of the stiffness of the newly formed ECM constituents. The improved understanding of the process of growth and development of ECM in these mechano-sensitive cell-scaffold systems will lead to more rational design and manufacturing of engineered tissues operating under highly demanding mechanical environments. PMID:27344402

Design and Validation of a Compressive Tissue Stimulator with High-Throughput Capacity and Real-Time Modulus Measurement Capability

PubMed Central

Salvetti, David J.; Pino, Christopher J.; Manuel, Steven G.; Dallmeyer, Ian; Rangarajan, Sanjeet V.; Meyer, Tobias; Kotov, Misha

2012-01-01

Mechanical stimulation has been shown to impact the properties of engineered hyaline cartilage constructs and is relevant for engineering of cartilage and osteochondral tissues. Most mechanical stimulators developed to date emphasize precision over adaptability to standard tissue culture equipment and protocols. The realization of mechanical characteristics in engineered constructs approaching native cartilage requires the optimization of complex variables (type of stimulus, regimen, and bimolecular signals). We have proposed and validated a stimulator design that focuses on high construct capacity, compatibility with tissue culture plastic ware, and regimen adaptability to maximize throughput. This design utilizes thin force sensors in lieu of a load cell and a linear encoder to verify position. The implementation of an individual force sensor for each sample enables the measurement of Young's modulus while stimulating the sample. Removable and interchangeable Teflon plungers mounted using neodymium magnets contact each sample. Variations in plunger height and design can vary the strain and force type on individual samples. This allows for the evaluation of a myriad of culture conditions and regimens simultaneously. The system was validated using contact accuracy, and Young's modulus measurements range as key parameters. Contact accuracy for the system was excellent within 1.16% error of the construct height in comparison to measurements made with a micrometer. Biomaterials ranging from bioceramics (cancellous bone, 123 MPa) to soft gels (1% agarose, 20 KPa) can be measured without any modification to the device. The accuracy of measurements in conjunction with the wide range of moduli tested demonstrate the unique characteristics of the device and the feasibility of using this device in mapping real-time changes to Young's modulus of tissue constructs (cartilage, bone) through the developmental phases in ex vivo culture conditions. PMID:21988089

Application of new optical coherence elastography to monitor the mineralization processing in bone tissue engineering constructs

NASA Astrophysics Data System (ADS)

Guan, Guangying; Song, Shaozhen; Huang, Zhihong; Yang, Ying

2015-03-01

Generation of functional tissue in vitro through tissue engineering technique is a promising direction to repair and replace malfunctioned organ and tissue in the modern medicine for various diseases which could not been treated well by conventional therapy. Similar to the embryo development, the generation of tissue in vitro is a highly dynamic processing. Obtaining the feedback of the processing real time is highly demanded. In this study, a new methodology has been explored aiming to monitor the morphological and mechanical property alteration of bone tissue engineering constructs simultaneously. Optical coherence elastography (OCE) equipped with a LDS V201 permanent magnet shaker and a modulated acoustic radiation force (ARF) to provide a vibration signal, has been used for the real time and non-destructive monitoring. A phantom construct system has been used to optimize the measurement conditions in which agar hydrogel with concentration from 0, 0.75 to 2% with/without hydroxyappatite particles have been injected to 3D porous poly (lactic acid) scaffolds to simulate the collagenous extracellular matrix (ECM) and mineralized ECM. The structural and elastography images of the constructs have clearly demonstrated the linear relation with the increased mechanical property versus the increase of agar concentration within the pores of the scaffolds. The MG63 bone cells seeded in the scaffolds and cultured for 4 weeks have been monitored by the established protocol exhibiting the increased mechanical strength in the pore wall where the ECM or mineralized ECM was assumed to be formed in comparison to empty pores. This study confirms that OCE-ARF could become a valuable tool in regenerative medicine to assess the biological events during in vitro culture and conditioning.

Biomimetic fetal rotation bioreactor for engineering bone tissues-Effect of cyclic strains on upregulation of osteogenic gene expression.

PubMed

Ravichandran, Akhilandeshwari; Wen, Feng; Lim, Jing; Chong, Mark Seow Khoon; Chan, Jerry K Y; Teoh, Swee-Hin

2018-04-01

Cells respond to physiological mechanical stresses especially during early fetal development. Adopting a biomimetic approach, it is necessary to develop bioreactor systems to explore the effects of physiologically relevant mechanical strains and shear stresses for functional tissue growth and development. This study introduces a multimodal bioreactor system that allows application of cyclic compressive strains on premature bone grafts that are cultured under biaxial rotation (chamber rotation about 2 axes) conditions for bone tissue engineering. The bioreactor is integrated with sensors for dissolved oxygen levels and pH that allow real-time, non-invasive monitoring of the culture parameters. Mesenchymal stem cells-seeded polycaprolactone-β-tricalcium phosphate scaffolds were cultured in this bioreactor over 2 weeks in 4 different modes-static, cyclic compression, biaxial rotation, and multimodal (combination of cyclic compression and biaxial rotation). The multimodal culture resulted in 1.8-fold higher cellular proliferation in comparison with the static controls within the first week. Two weeks of culture in the multimodal bioreactor utilizing the combined effects of optimal fluid flow conditions and cyclic compression led to the upregulation of osteogenic genes alkaline phosphatase (3.2-fold), osteonectin (2.4-fold), osteocalcin (10-fold), and collagen type 1 α1 (2-fold) in comparison with static cultures. We report for the first time, the independent and combined effects of mechanical stimulation and biaxial rotation for bone tissue engineering using a bioreactor platform with non-invasive sensing modalities. The demonstrated results show leaning towards the futuristic vision of using a physiologically relevant bioreactor system for generation of autologous bone grafts for clinical implantation. Copyright © 2018 John Wiley & Sons, Ltd.

Turntable mechanism

NASA Technical Reports Server (NTRS)

Myers, William Neill (Inventor)

1993-01-01

In vacuum plasma spraying a turntable must be provided which not only makes it possible to rotate and tilt a heavy workpiece, but to operate at vacuum plasma temperatures to do so. In the vacuum plasma coating of large parts such as combustion chambers of rocket engines, the workpiece must not only be rotated, but it must be tilted. Hence, the turntable must be capable not only of supporting heavy parts, but of angulating such heavy workpieces. And this must be done without drive means failure due to extremely high temperatures under which the turntable mechanism is operated. A turntable mechanism is provided which is capable of operating under such conditions. For cooling the turntable drive mechanism, internal cooling means are included.

Lunar surface engineering properties experiment definition. Volume 2: Mechanics of rolling sphere-soil slope interaction

NASA Technical Reports Server (NTRS)

Hovland, H. J.; Mitchell, J. K.

1971-01-01

The soil deformation mode under the action of a rolling sphere (boulder) was determined, and a theory based on actual soil failure mechanism was developed which provides a remote reconnaissance technique for study of soil conditions using boulder track observations. The failure mechanism was investigated by using models and by testing an instrumented spherical wheel. The wheel was specifically designed to measure contact pressure, but it also provided information on the failure mechanism. Further tests included rolling some 200 spheres down sand slopes. Films were taken of the rolling spheres, and the tracks were measured. Implications of the results and reevaluation of the lunar boulder tracks are discussed.

Genetically Engineered Materials for Biofuels Production

NASA Astrophysics Data System (ADS)

Raab, Michael

2012-02-01

Agrivida, Inc., is an agricultural biotechnology company developing industrial crop feedstocks for the fuel and chemical industries. Agrivida's crops have improved processing traits that enable efficient, low cost conversion of the crops' cellulosic components into fermentable sugars. Currently, pretreatment and enzymatic conversion of the major cell wall components, cellulose and hemicellulose, into fermentable sugars is the most expensive processing step that prevents widespread adoption of biomass in biofuels processes. To lower production costs we are consolidating pretreatment and enzyme production within the crop. In this strategy, transgenic plants express engineered cell wall degrading enzymes in an inactive form, which can be reactivated after harvest. We have engineered protein elements that disrupt enzyme activity during normal plant growth. Upon exposure to specific processing conditions, the engineered enzymes are converted into their active forms. This mechanism significantly lowers pretreatment costs and enzyme loadings (>75% reduction) below those currently available to the industry.

Electric converters of electromagnetic strike machine with battery power

NASA Astrophysics Data System (ADS)

Usanov, K. M.; Volgin, A. V.; Kargin, V. A.; Moiseev, A. P.; Chetverikov, E. A.

2018-03-01

At present, the application of pulse linear electromagnetic engines to drive strike machines for immersion of rod elements into the soil, strike drilling of shallow wells, dynamic probing of soils is recognized as quite effective. The pulse linear electromagnetic engine performs discrete consumption and conversion of electrical energy into mechanical work. Pulse dosing of a stream transmitted by the battery source to the pulse linear electromagnetic engine of the energy is provided by the electrical converter. The electric converters with the control of an electromagnetic strike machine as functions of time and armature movement, which form the unipolar supply pulses of voltage and current necessary for the normal operation of a pulse linear electromagnetic engine, are proposed. Electric converters are stable in operation, implement the necessary range of output parameters control determined by the technological process conditions, have noise immunity and automatic disconnection of power supply in emergency modes.

A computational continuum model of poroelastic beds

PubMed Central

Zampogna, G. A.

2017-01-01

Despite the ubiquity of fluid flows interacting with porous and elastic materials, we lack a validated non-empirical macroscale method for characterizing the flow over and through a poroelastic medium. We propose a computational tool to describe such configurations by deriving and validating a continuum model for the poroelastic bed and its interface with the above free fluid. We show that, using stress continuity condition and slip velocity condition at the interface, the effective model captures the effects of small changes in the microstructure anisotropy correctly and predicts the overall behaviour in a physically consistent and controllable manner. Moreover, we show that the performance of the effective model is accurate by validating with fully microscopic resolved simulations. The proposed computational tool can be used in investigations in a wide range of fields, including mechanical engineering, bio-engineering and geophysics. PMID:28413355

Introductory Education for Mechanical Engineering by Exercise in Mechanical Disassembly

NASA Astrophysics Data System (ADS)

Matsui, Yoshio; Asakawa, Naoki; Iwamori, Satoru

An introductory program “Exercise for engineers in mechanical disassembly” is an exercise that ten students of every team disassemble a motor scooter to the components and then assemble again to the initial form in 15 weeks. The purpose of this program is to introduce mechanical engineering by touching the real machine and learning how it is composed from various mechanical parts to the students at the early period after the entrance into the university. Additional short lectures by young teachers and a special lecture by a top engineer in the industry encourage the students to combine the actual machine and the mechanical engineering subjects. Furthermore, various educations such as group leader system, hazard prediction training, parts filing are included in this program. As a result, students recognize the importance of the mechanical engineering study and the way of group working.

Recellularization of decellularized heart valves: Progress toward the tissue-engineered heart valve

PubMed Central

VeDepo, Mitchell C; Detamore, Michael S; Hopkins, Richard A; Converse, Gabriel L

2017-01-01

The tissue-engineered heart valve portends a new era in the field of valve replacement. Decellularized heart valves are of great interest as a scaffold for the tissue-engineered heart valve due to their naturally bioactive composition, clinical relevance as a stand-alone implant, and partial recellularization in vivo. However, a significant challenge remains in realizing the tissue-engineered heart valve: assuring consistent recellularization of the entire valve leaflets by phenotypically appropriate cells. Many creative strategies have pursued complete biological valve recellularization; however, identifying the optimal recellularization method, including in situ or in vitro recellularization and chemical and/or mechanical conditioning, has proven difficult. Furthermore, while many studies have focused on individual parameters for increasing valve interstitial recellularization, a general understanding of the interacting dynamics is likely necessary to achieve success. Therefore, the purpose of this review is to explore and compare the various processing strategies used for the decellularization and subsequent recellularization of tissue-engineered heart valves. PMID:28890780

Microelectrical Mechanical Systems Flow Control Used to Manage Engine Face Distortion in Compact Inlet Systems

NASA Technical Reports Server (NTRS)

Anderson, Bernhard H.; Miller, Daniel N.

1999-01-01

Turbofan engine-face flow distortion is one of the most troublesome and least understood problems for designers of modern engine inlet systems. One concern is that there are numerous sources of flow-field distortion that are ingested by the inlet or generated within the inlet duct itself. Among these are: (1) flow separation at the cowl lip during in-flight maneuvering, (2) flow separation on the compression surfaces due to shock-wave/boundary layer interactions, (3) spillage of the fuselage boundary layer into the inlet duct, (4) ingestion of aircraft vortices and wakes emanating from upstream disturbances, and (5) strong secondary flow gradients and flow separation induced by wall curvature within the inlet duct itself. Most developing aircraft (including the B70, F-111, F-14, Mig-25, Tornado, and Airbus A300) have experienced one or more of these types of problems, particularly at high Mach numbers and/or extreme maneuver conditions when flow distortion at the engine face exceeded the allowable limits of the engine.

Evidence of Facilitation Cascade Processes as Drivers of Successional Patterns of Ecosystem Engineers at the Upper Altitudinal Limit of the Dry Puna.

PubMed

Malatesta, Luca; Tardella, Federico Maria; Piermarteri, Karina; Catorci, Andrea

2016-01-01

Facilitation processes constitute basic elements of vegetation dynamics in harsh systems. Recent studies in tropical alpine environments demonstrated how pioneer plant species defined as "ecosystem engineers" are capable of enhancing landscape-level richness by adding new species to the community through the modification of microhabitats, and also provided hints about the alternation of different ecosystem engineers over time. Nevertheless, most of the existing works analysed different ecosystem engineers separately, without considering the interaction of different ecosystem engineers. Focusing on the altitudinal limit of Peruvian Dry Puna vegetation, we hypothesized that positive interactions structure plant communities by facilitation cascades involving different ecosystem engineers, determining the evolution of the microhabitat patches in terms of abiotic resources and beneficiary species hosted. To analyze successional mechanisms, we used a "space-for-time" substitution to account for changes over time, and analyzed data on soil texture, composition, and temperature, facilitated species and their interaction with nurse species, and surface area of engineered patches by means of chemical analyses, indicator species analysis, and rarefaction curves. A successional process, resulting from the dynamic interaction of different ecosystem engineers, which determined a progressive amelioration of soil conditions (e.g. nitrogen and organic matter content, and temperature), was the main driver of species assemblage at the community scale, enhancing species richness. Cushion plants act as pioneers, by starting the successional processes that continue with shrubs and tussocks. Tussock grasses have sometimes been found to be capable of creating microhabitat patches independently. The dynamics of species assemblage seem to follow the nested assemblage mechanism, in which the first foundation species to colonize a habitat provides a novel substrate for colonization by other foundation species through a facilitation cascade process.

Nonlinear Inelastic Mechanical Behavior Of Epoxy Resin Polymeric Materials

NASA Astrophysics Data System (ADS)

Yekani Fard, Masoud

Polymer and polymer matrix composites (PMCs) materials are being used extensively in different civil and mechanical engineering applications. The behavior of the epoxy resin polymers under different types of loading conditions has to be understood before the mechanical behavior of Polymer Matrix Composites (PMCs) can be accurately predicted. In many structural applications, PMC structures are subjected to large flexural loadings, examples include repair of structures against earthquake and engine fan cases. Therefore it is important to characterize and model the flexural mechanical behavior of epoxy resin materials. In this thesis, a comprehensive research effort was undertaken combining experiments and theoretical modeling to investigate the mechanical behavior of epoxy resins subject to different loading conditions. Epoxy resin E 863 was tested at different strain rates. Samples with dog-bone geometry were used in the tension tests. Small sized cubic, prismatic, and cylindrical samples were used in compression tests. Flexural tests were conducted on samples with different sizes and loading conditions. Strains were measured using the digital image correlation (DIC) technique, extensometers, strain gauges, and actuators. Effects of triaxiality state of stress were studied. Cubic, prismatic, and cylindrical compression samples undergo stress drop at yield, but it was found that only cubic samples experience strain hardening before failure. Characteristic points of tensile and compressive stress strain relation and load deflection curve in flexure were measured and their variations with strain rate studied. Two different stress strain models were used to investigate the effect of out-of-plane loading on the uniaxial stress strain response of the epoxy resin material. The first model is a strain softening with plastic flow for tension and compression. The influence of softening localization on material behavior was investigated using the DIC system. It was found that compression plastic flow has negligible influence on flexural behavior in epoxy resins, which are stronger in pre-peak and post-peak softening in compression than in tension. The second model was a piecewise-linear stress strain curve simplified in the post-peak response. Beams and plates with different boundary conditions were tested and analytically studied. The flexural over-strength factor for epoxy resin polymeric materials were also evaluated.

Compendium of Abstracts on Statistical Applications in Geotechnical Engineering.

DTIC Science & Technology

1983-09-01

research in the application of probabilistic and statistical methods to soil mechanics, rock mechanics, and engineering geology problems have grown markedly...probability, statistics, soil mechanics, rock mechanics, and engineering geology. 2. The purpose of this report is to make available to the U. S...Deformation Dynamic Response Analysis Seepage, Soil Permeability and Piping Earthquake Engineering, Seismology, Settlement and Heave Seismic Risk Analysis

Magnetically actuated tissue engineered scaffold: insights into mechanism of physical stimulation

NASA Astrophysics Data System (ADS)

Sapir-Lekhovitser, Yulia; Rotenberg, Menahem Y.; Jopp, Juergen; Friedman, Gary; Polyak, Boris; Cohen, Smadar

2016-02-01

Providing the right stimulatory conditions resulting in efficient tissue promoting microenvironment in vitro and in vivo is one of the ultimate goals in tissue development for regenerative medicine. It has been shown that in addition to molecular signals (e.g. growth factors) physical cues are also required for generation of functional cell constructs. These cues are particularly relevant to engineering of biological tissues, within which mechanical stress activates mechano-sensitive receptors, initiating biochemical pathways which lead to the production of functionally mature tissue. Uniform magnetic fields coupled with magnetizable nanoparticles embedded within three dimensional (3D) scaffold structures remotely create transient physical forces that can be transferrable to cells present in close proximity to the nanoparticles. This study investigated the hypothesis that magnetically responsive alginate scaffold can undergo reversible shape deformation due to alignment of scaffold's walls in a uniform magnetic field. Using custom made Helmholtz coil setup adapted to an Atomic Force Microscope we monitored changes in matrix dimensions in situ as a function of applied magnetic field, concentration of magnetic particles within the scaffold wall structure and rigidity of the matrix. Our results show that magnetically responsive scaffolds exposed to an externally applied time-varying uniform magnetic field undergo a reversible shape deformation. This indicates on possibility of generating bending/stretching forces that may exert a mechanical effect on cells due to alternating pattern of scaffold wall alignment and relaxation. We suggest that the matrix structure deformation is produced by immobilized magnetic nanoparticles within the matrix walls resulting in a collective alignment of scaffold walls upon magnetization. The estimated mechanical force that can be imparted on cells grown on the scaffold wall at experimental conditions is in the order of 1 pN, which correlates well with reported threshold to induce mechanotransduction effects on cellular level. This work is our next step in understanding of how to accurately create proper stimulatory microenvironment for promotion of cellular organization to form mature tissue engineered constructs.

Magnetically actuated tissue engineered scaffold: insights into mechanism of physical stimulation

PubMed Central

Sapir-Lekhovitser, Yulia; Rotenberg, Menahem Y.; Jopp, Juergen; Friedman, Gary; Polyak, Boris; Cohen, Smadar

2016-01-01

Providing the right stimulatory conditions resulting in efficient tissue promoting microenvironment in vitro and in vivo is one of the ultimate goals in tissue development for regenerative medicine. It has been shown that in addition to molecular signals (e.g. growth factors) physical cues are also required for generation of functional cell constructs. These cues are particularly relevant to engineering of biological tissues, within which mechanical stress activates mechano-sensitive receptors, initiating biochemical pathways which lead to the production of functionally mature tissue. Uniform magnetic fields coupled with magnetizable nanoparticles embedded within three dimensional (3D) scaffold structures remotely create transient physical forces that can be transferrable to cells present in close proximity to the nanoparticles. This study investigated the hypothesis that magnetically responsive alginate scaffold can undergo reversible shape deformation due to alignment of scaffold’s walls in a uniform magnetic field. Using custom made Helmholtz coil setup adapted to an Atomic Force Microscope we monitored changes in matrix dimensions in situ as a function of applied magnetic field, concentration of magnetic particles within the scaffold wall structure and rigidity of the matrix. Our results show that magnetically responsive scaffolds exposed to an externally applied time-varying uniform magnetic field undergo a reversible shape deformation. This indicates on possibility of generating bending/stretching forces that may exert a mechanical effect on cells due to alternating pattern of scaffold wall alignment and relaxation. We suggest that the matrix structure deformation is produced by immobilized magnetic nanoparticles within the matrix walls resulting in a collective alignment of scaffold walls upon magnetization. The estimated mechanical force that can be imparted on cells grown on the scaffold wall at experimental conditions is in the order of 1 pN, which correlates well with reported threshold to induce mechanotransduction effects on cellular level. This work is our next step in understanding of how to accurately create proper stimulatory microenvironment for promotion of cellular organization to form mature tissue engineered constructs. PMID:26790538

Mechanism reduction for multicomponent surrogates: A case study using toluene reference fuels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Niemeyer, Kyle E.; Sung, Chih-Jen

Strategies and recommendations for performing skeletal reductions of multicomponent surrogate fuels are presented, through the generation and validation of skeletal mechanisms for a three-component toluene reference fuel. Using the directed relation graph with error propagation and sensitivity analysis method followed by a further unimportant reaction elimination stage, skeletal mechanisms valid over comprehensive and high-temperature ranges of conditions were developed at varying levels of detail. These skeletal mechanisms were generated based on autoignition simulations, and validation using ignition delay predictions showed good agreement with the detailed mechanism in the target range of conditions. When validated using phenomena other than autoignition, suchmore » as perfectly stirred reactor and laminar flame propagation, tight error control or more restrictions on the reduction during the sensitivity analysis stage were needed to ensure good agreement. In addition, tight error limits were needed for close prediction of ignition delay when varying the mixture composition away from that used for the reduction. In homogeneous compression-ignition engine simulations, the skeletal mechanisms closely matched the point of ignition and accurately predicted species profiles for lean to stoichiometric conditions. Furthermore, the efficacy of generating a multicomponent skeletal mechanism was compared to combining skeletal mechanisms produced separately for neat fuel components; using the same error limits, the latter resulted in a larger skeletal mechanism size that also lacked important cross reactions between fuel components. Based on the present results, general guidelines for reducing detailed mechanisms for multicomponent fuels are discussed.« less

Mechanism reduction for multicomponent surrogates: A case study using toluene reference fuels

DOE PAGES

Niemeyer, Kyle E.; Sung, Chih-Jen

2014-11-01

Strategies and recommendations for performing skeletal reductions of multicomponent surrogate fuels are presented, through the generation and validation of skeletal mechanisms for a three-component toluene reference fuel. Using the directed relation graph with error propagation and sensitivity analysis method followed by a further unimportant reaction elimination stage, skeletal mechanisms valid over comprehensive and high-temperature ranges of conditions were developed at varying levels of detail. These skeletal mechanisms were generated based on autoignition simulations, and validation using ignition delay predictions showed good agreement with the detailed mechanism in the target range of conditions. When validated using phenomena other than autoignition, suchmore » as perfectly stirred reactor and laminar flame propagation, tight error control or more restrictions on the reduction during the sensitivity analysis stage were needed to ensure good agreement. In addition, tight error limits were needed for close prediction of ignition delay when varying the mixture composition away from that used for the reduction. In homogeneous compression-ignition engine simulations, the skeletal mechanisms closely matched the point of ignition and accurately predicted species profiles for lean to stoichiometric conditions. Furthermore, the efficacy of generating a multicomponent skeletal mechanism was compared to combining skeletal mechanisms produced separately for neat fuel components; using the same error limits, the latter resulted in a larger skeletal mechanism size that also lacked important cross reactions between fuel components. Based on the present results, general guidelines for reducing detailed mechanisms for multicomponent fuels are discussed.« less

Teaching Continuum Mechanics in a Mechanical Engineering Program

ERIC Educational Resources Information Center

Liu, Yucheng

2011-01-01

This paper introduces a graduate course, continuum mechanics, which is designed for and taught to graduate students in a Mechanical Engineering (ME) program. The significance of continuum mechanics in engineering education is demonstrated and the course structure is described. Methods used in teaching this course such as topics, class…

Effect of post injections on mixture preparation and unburned hydrocarbon emissions in a heavy-duty diesel engine

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Connor, Jacqueline; Musculus, Mark P. B.; Pickett, Lyle M.

This work explores the mechanisms by which a post injection can reduce unburned hydrocarbon (UHC) emissions in heavy-duty diesel engines operating at low-temperature combustion conditions. Post injections, small, close-coupled injections of fuel after the main injection, have been shown to reduce UHC in the authors’ previous work. In this work, we analyze optical data from laser-induced fluorescence of both CH 2O and OH and use chemical reactor modeling to better understand the mechanism by which post injections reduce UHC emissions. The results indicate that post-injection efficacy, or the extent to which a post injection reduces UHC emissions, is a strongmore » function of the cylinder pressure variation during the post injection. However, the data and analysis indicate that the pressure and temperature rise from the post injection combustion cannot solely explain the UHC reduction measured by both engine-out and optical diagnostics. In conclusion, the fluid-mechanic, thermal, and chemical interaction of the post injection with the main-injection mixture is a key part of UHC reduction; the starting action of the post jet and the subsequent entrainment of surrounding gases are likely both important processes in reducing UHC with a post injection.« less

Effect of post injections on mixture preparation and unburned hydrocarbon emissions in a heavy-duty diesel engine

DOE PAGES

O'Connor, Jacqueline; Musculus, Mark P. B.; Pickett, Lyle M.

2016-05-30

This work explores the mechanisms by which a post injection can reduce unburned hydrocarbon (UHC) emissions in heavy-duty diesel engines operating at low-temperature combustion conditions. Post injections, small, close-coupled injections of fuel after the main injection, have been shown to reduce UHC in the authors’ previous work. In this work, we analyze optical data from laser-induced fluorescence of both CH 2O and OH and use chemical reactor modeling to better understand the mechanism by which post injections reduce UHC emissions. The results indicate that post-injection efficacy, or the extent to which a post injection reduces UHC emissions, is a strongmore » function of the cylinder pressure variation during the post injection. However, the data and analysis indicate that the pressure and temperature rise from the post injection combustion cannot solely explain the UHC reduction measured by both engine-out and optical diagnostics. In conclusion, the fluid-mechanic, thermal, and chemical interaction of the post injection with the main-injection mixture is a key part of UHC reduction; the starting action of the post jet and the subsequent entrainment of surrounding gases are likely both important processes in reducing UHC with a post injection.« less

Self-lubricating Al-WS2 composites for efficient and greener tribological parts.

PubMed

Niste, Vlad Bogdan; Ratoi, Monica; Tanaka, Hiroyoshi; Xu, Fang; Zhu, Yanqiu; Sugimura, Joichi

2017-11-07

Due to their mechanical and physical properties, aluminium alloys possess wide potential in the automotive industry, particularly in hot reciprocating applications such as pistons for diesel and petrol engines. WS 2 particle-reinforced composites could bring further improvements by reducing friction and wear between moving parts. Reducing friction improves efficiency by lowering energy/fuel use, ultimately leading to lower greenhouse gas emissions, while antiwear properties can prolong component life. This study compares for the first time the tribological performance of powder metallurgy-consolidated Al composites reinforced with either IF- or 2H-WS 2 particles, so as to elucidate their mechanism of action in test conditions similar to those encountered in engine applications. The composites were tested in lubricated reciprocating contacts against AISI52100 steel balls and the impact of WS 2 could be seen at both 25 and 100 °C. The reduced friction and wear at ambient temperature is due to the predominantly physical mechanism of action of WS 2 , while the best antiwear performance is measured at elevated (standard operating engine) temperatures that promote the chemical reaction of WS 2 with the aluminium matrix. The investigation focused on studying the wear tracks/scars and the tribofilms generated on the composite and ball with optical profilometry, SEM, XPS and Auger spectroscopy.

Reusable rocket engine turbopump health monitoring system, part 3

NASA Technical Reports Server (NTRS)

Perry, John G.

1989-01-01

Degradation mechanisms and sensor identification/selection resulted in a list of degradation modes and a list of sensors that are utilized in the diagnosis of these degradation modes. The sensor list is divided into primary and secondary indicators of the corresponding degradation modes. The signal conditioning requirements are discussed, describing the methods of producing the Space Shuttle Main Engine (SSME) post-hot-fire test data to be utilized by the Health Monitoring System. Development of the diagnostic logic and algorithms is also presented. The knowledge engineering approach, as utilized, includes the knowledge acquisition effort, characterization of the expert's problem solving strategy, conceptually defining the form of the applicable knowledge base, and rule base, and identifying an appropriate inferencing mechanism for the problem domain. The resulting logic flow graphs detail the diagnosis/prognosis procedure as followed by the experts. The nature and content of required support data and databases is also presented. The distinction between deep and shallow types of knowledge is identified. Computer coding of the Health Monitoring System is shown to follow the logical inferencing of the logic flow graphs/algorithms.

Engineering mechanical gradients in next generation biomaterials - Lessons learned from medical textile design.

PubMed

Ng, Joanna L; Collins, Ciara E; Knothe Tate, Melissa L

2017-07-01

Nonwoven and textile membranes have been applied both externally and internally to prescribe boundary conditions for medical conditions as diverse as oedema and tissue defects. Incorporation of mechanical gradients in next generation medical membrane design offers great potential to enhance function in a dynamic, physiological context. Yet the gradient properties and resulting mechanical performance of current membranes are not well described. To bridge this knowledge gap, we tested and compared the mechanical properties of bounding membranes used in both external (compression sleeves for oedema, exercise bands) and internal (surgical membranes) physiological contexts. We showed that anisotropic compression garment textiles, isotropic exercise bands and surgical membranes exhibit similar ranges of resistance to tension under physiologic strains. However, their mechanical gradients and resulting stress-strain relationships show differences in work capacity and energy expenditure. Exercise bands' moduli of elasticity and respective thicknesses allow for controlled, incremental increases in loading to facilitate healing as injured tissues return to normal structure and function. In contrast, the gradients intrinsic to compression sleeve design exhibit gaps in the middle range (1-5N) of physiological strains and also inconsistencies along the length of the sleeve, resulting in less than optimal performance of these devices. These current shortcomings in compression textile and garment design may be addressed in the future through implementation of novel approaches. For example, patterns, fibre compositions, and fibre anisotropy can be incorporated into biomaterial design to achieve seamless mechanical gradients in structure and resulting dynamic function, which would be particularly useful in physiological contexts. These concepts can be applied further to biomaterial design to deliver pressure gradients during movement of oedematous limbs (compression garments) and facilitate transport of molecules and cells during tissue genesis within tissue defects (surgical membranes). External and internal biomaterial membranes prescribe boundary conditions for treatment of medical disorders, from oedema to tissue defects. Studies are needed to guide the design of next generation biomaterials and devices that incorporate gradient engineering approaches, which offer great potential to enhance function in a dynamic and physiological context. Mechanical gradients intrinsic to currently implemented biomaterials such as medical textiles and surgical interface membranes are poorly understood. Here we characterise quantitatively the mechanics of textile and nonwoven biomaterial membranes for external and internal use. The lack of seamless gradients in compression medical textiles contrasts with the graded mechanical effects achieved by elastomeric exercise bands, which are designed to deliver controlled, incremental increases in loading to facilitate healing as injured tissues return to normal structure and function. Engineering textiles with a prescient choice of fibre composition/size, type of knit/weave and inlay fibres, and weave density/anisotropy will enable creation of fabrics that can deliver spatially and temporally controlled mechanical gradients to maintain force balances at tissue boundaries, e.g. to treat oedema or tissue defects. Copyright © 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

Air Force Center of Excellence on Bio-nano-enabled Inorganic/Organic Nanostructures and Improved Cognition (BIONIC)

DTIC Science & Technology

2015-01-09

IRG #3)  Mostafa A. El-Sayed, School of Chemistry & Biochemistry (IRG #2)  Andrei Fedorov, School of Mechanical Engineering (IRG #2)  Michael A...Engineering, U.S. Citizen)  *David Anderson (Ph.D. student, School of Mechanical Engineering, U.S. Citizen)  Luke A. Beardslee (Ph.D. student, School...Songkil Kim (PhD student, School of Mechanical Engineering)  Philip Kwon (Ph.D. student, School of Mechanical Engineering, U.S. Citizen)  Erin Lightman

Effect of oxidation products on service properties of motor oils

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhitova, T.Yu.; Polipanov, I.S.

1995-01-01

One of the most urgent problems in chemmotology is how to create in an engine - lube oil system a controllable tribochemical process for the purpose of stabilizing the service properties of the oil and forming protective surface structures on the engine parts in order to minimize wear. The complexity of this problem reflects the diversity of the processes taking place in the tribological system. It is impossible to elucidate the mechanism of tribochemical reactions without studying the influence of changes in the oil composition and structure on its service properties during the course of operation. If the relationships involvedmore » in this influence are defined, it will become possible to change the structure of the oil in the desired direction and to achieve the desired service properties. For our studies we selected the motor oil M-10-G{sub 2}, conforming to GOST 8581-78. Samples of this oil were drawn during test-stand evaluations of D-144 and D-144-60 tractor diesels without any oil changes these tests were conducted jointly by the Institute of Problems in Mechanical Engineering of the Russian Academy of Sciences, the Scientific-Research and Design-Technology Institute of Tractor and Combine Engines (NIKTID), and the Vladimir Tractor Plant Production Association. Tests were run for 1000 h with the standard conditions and test sequence, and for 1500 and 2300 h under conditions of a {open_quotes}constantly acting tribochemical regime{close_quotes}. Oil samples were drawn at 50-100 h intervals and tested by standard methods to determine the following physico-chemical characteristics: kinematic viscosity, acid and base numbers, ash, carbon residue, content of insoluble sludge, and content of particulate contaminant.« less

TexMi: Development of Tissue-Engineered Textile-Reinforced Mitral Valve Prosthesis

PubMed Central

Moreira, Ricardo; Gesche, Valentine N.; Hurtado-Aguilar, Luis G.; Schmitz-Rode, Thomas; Frese, Julia

2014-01-01

Mitral valve regurgitation together with aortic stenosis is the most common valvular heart disease in Europe and North America. Mechanical and biological prostheses available for mitral valve replacement have significant limitations such as the need of a long-term anticoagulation therapy and failure by calcifications. Both types are unable to remodel, self-repair, and adapt to the changing hemodynamic conditions. Moreover, they are mostly designed for the aortic position and do not reproduce the native annular-ventricular continuity, resulting in suboptimal hemodynamics, limited durability, and gradually decreasing ventricular pumping efficiency. A tissue-engineered heart valve specifically designed for the mitral position has the potential to overcome the limitations of the commercially available substitutes. For this purpose, we developed the TexMi, a living textile-reinforced mitral valve, which recapitulates the key elements of the native one: annulus, asymmetric leaflets (anterior and posterior), and chordae tendineae to maintain the native annular-ventricular continuity. The tissue-engineered valve is based on a composite scaffold consisting of the fibrin gel as a cell carrier and a textile tubular structure with the twofold task of defining the gross three-dimensional (3D) geometry of the valve and conferring mechanical stability. The TexMi valves were molded with ovine umbilical vein cells and stimulated under dynamic conditions for 21 days in a custom-made bioreactor. Histological and immunohistological stainings showed remarkable tissue development with abundant aligned collagen fibers and elastin deposition. No cell-mediated tissue contraction occurred. This study presents the proof-of-principle for the realization of a tissue-engineered mitral valve with a simple and reliable injection molding process readily adaptable to the patient's anatomy and pathological situation by producing a patient-specific rapid prototyped mold. PMID:24665896

Engineering zonal cartilaginous tissue by modulating oxygen levels and mechanical cues through the depth of infrapatellar fat pad stem cell laden hydrogels.

PubMed

Luo, Lu; O'Reilly, Adam R; Thorpe, Stephen D; Buckley, Conor T; Kelly, Daniel J

2017-09-01

Engineering tissues with a structure and spatial composition mimicking those of native articular cartilage (AC) remains a challenge. This study examined if infrapatellar fat pad-derived stem cells (FPSCs) can be used to engineer cartilage grafts with a bulk composition and a spatial distribution of matrix similar to the native tissue. In an attempt to mimic the oxygen gradients and mechanical environment within AC, FPSC-laden hydrogels (either 2 mm or 4 mm in height) were confined to half of their thickness and/or subjected to dynamic compression (DC). Confining FPSC-laden hydrogels was predicted to accentuate the gradient in oxygen tension through the depth of the constructs (higher in the top and lower in the bottom), leading to enhanced glycosaminoglycan (GAG) and collagen synthesis in 2 mm high tissues. When subjected to DC alone, both GAG and collagen accumulation increased within 2 mm high unconfined constructs. Furthermore, the dynamic modulus of constructs increased from 0.96 MPa to 1.45 MPa following the application of DC. There was no synergistic benefit of coupling confinement and DC on overall levels of matrix accumulation; however in all constructs, irrespective of their height, the combination of these boundary conditions led to the development of engineered tissues that spatially best resembled native AC. The superficial region of these constructs mimicked that of native tissue, staining weakly for GAG, strongly for type II collagen, and in 4 mm high tissues more intensely for proteoglycan 4 (lubricin). This study demonstrated that FPSCs respond to joint-like environmental conditions by producing cartilage tissues mimicking native AC. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Fabrication of injectable high strength hydrogel based on 4-arm star PEG for cartilage tissue engineering.

PubMed

Wang, Jianqi; Zhang, Fengjie; Tsang, Wing Pui; Wan, Chao; Wu, Chi

2017-03-01

Hydrogels prepared from poly(ethylene glycol) (PEG) are widely applied in tissue engineering, especially those derived from a combination of functional multi-arm star PEG and linear crosslinker, with an expectation to form a structurally ideal network. However, the poor mechanical strength still renders their further applications. Here we examined the relationship between the dynamics of the pre-gel solution and the mechanical property of the resultant hydrogel in a system consisting of 4-arm star PEG functionalized with vinyl sulfone and short dithiol crosslinker. A method to prepare mechanically strong hydrogel for cartilage tissue engineering is proposed. It is found that when gelation takes place at the overlap concentration, at which a slow relaxation mode just appears in dynamic light scattering (DLS), the resultant hydrogel has a local maximum compressive strength ∼20 MPa, while still keeps ultralow mass concentration and Young's modulus. Chondrocyte-laden hydrogel constructed under this condition was transplanted into the subcutaneous pocket and an osteochondral defect model in SCID mice. The in vivo results show that chondrocytes can proliferate and maintain their phenotypes in the hydrogel, with the production of abundant extracellular matrix (ECM) components, formation of typical chondrocyte lacunae structure and increase in Young's modulus over 12 weeks, as indicated by histological, immunohistochemistry, gene expression analyses and mechanical test. Moreover, newly formed hyaline cartilage was observed to be integrated with the host articular cartilage tissue in the defects injected with chondrocytes/hydrogel constructs. The results suggest that this hydrogel is a promising candidate scaffold for cartilage tissue engineering. Copyright © 2016 Elsevier Ltd. All rights reserved.

Oxidation characteristics of gasoline direct-injection (GDI) engine soot: Catalytic effects of ash and modified kinetic correlation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Choi, Seungmok; Seong, Heeje

In this paper, experimental analyses are conducted into the GDI soot oxidation characteristics as dependent on engine operating conditions. Soot is sampled at various engine operating conditions of a commercial 2.4 L GDI engine with a naturally aspirated, homogeneous, and stoichiometric operation strategy. The oxidation reactivity, ash composition, and carbon nanostructure of the GDI soot samples are analyzed using thermogravimetric analysis (TGA), scanning electron microscope–energy-dispersive spectroscopy (SEM-EDS), high-resolution transmission electron microscopy (HR-TEM), and Raman spectroscopy. Based on the analyses, a global GDI soot oxidation mechanism is proposed which includes the effects of soluble organic fractions (SOF)/weakly bonded carbon (WBC), andmore » three types of ash on GDI soot oxidation. The results show that GDI soot contains an order of magnitude higher ash fraction than does conventional diesel soot, and oxidation reactivity is significantly enhanced by the catalytic effects of ash, as a function of ash content in soot. A modified empirical kinetic correlation for GDI soot oxidation is suggested on the basis of the results, and the modified kinetic correlation predicts the GDI soot oxidation rate accurately for various engine operation points at wide ranges of soot conversion and temperature without modifying kinetic parameters. The kinetic parameters are determined from isothermal and non-isothermal thremogravimetric analysis (TGA) soot oxidation tests; the methods are elucidated in detail.« less

Oxidation characteristics of gasoline direct-injection (GDI) engine soot: Catalytic effects of ash and modified kinetic correlation

DOE PAGES

Choi, Seungmok; Seong, Heeje

2015-03-02

In this paper, experimental analyses are conducted into the GDI soot oxidation characteristics as dependent on engine operating conditions. Soot is sampled at various engine operating conditions of a commercial 2.4 L GDI engine with a naturally aspirated, homogeneous, and stoichiometric operation strategy. The oxidation reactivity, ash composition, and carbon nanostructure of the GDI soot samples are analyzed using thermogravimetric analysis (TGA), scanning electron microscope–energy-dispersive spectroscopy (SEM-EDS), high-resolution transmission electron microscopy (HR-TEM), and Raman spectroscopy. Based on the analyses, a global GDI soot oxidation mechanism is proposed which includes the effects of soluble organic fractions (SOF)/weakly bonded carbon (WBC), andmore » three types of ash on GDI soot oxidation. The results show that GDI soot contains an order of magnitude higher ash fraction than does conventional diesel soot, and oxidation reactivity is significantly enhanced by the catalytic effects of ash, as a function of ash content in soot. A modified empirical kinetic correlation for GDI soot oxidation is suggested on the basis of the results, and the modified kinetic correlation predicts the GDI soot oxidation rate accurately for various engine operation points at wide ranges of soot conversion and temperature without modifying kinetic parameters. The kinetic parameters are determined from isothermal and non-isothermal thremogravimetric analysis (TGA) soot oxidation tests; the methods are elucidated in detail.« less

Microstructural indicators of transition mechanisms in time-dependent fatigue crack growth in nickel base superalloys

NASA Astrophysics Data System (ADS)

Heeter, Ann E.

Gas turbine engines are an important part of power generation in modern society, especially in the field of aerospace. Aerospace engines are design to last approximately 30 years and the engine components must be designed to survive for the life of the engine or to be replaced at regular intervals to ensure consumer safety. Fatigue crack growth analysis is a vital component of design for an aerospace component. Crack growth modeling and design methods date back to an origin around 1950 with a high rate of accuracy. The new generation of aerospace engines is designed to be efficient as possible and require higher operating temperatures than ever seen before in previous generations. These higher temperatures place more stringent requirements on the material crack growth performance under creep and time dependent conditions. Typically the types of components which are subject to these requirements are rotating disk components which are made from advanced materials such as nickel base superalloys. Traditionally crack growth models have looked at high temperature crack growth purely as a function of temperature and assumed that all crack growth was either controlled by a cycle dependent or time dependent mechanism. This new analysis is trying to evaluate the transition between cycle-dependent and time-dependent mechanism and the microstructural markers that characterize this transitional behavior. The physical indications include both the fracture surface morphology as well as the shape of the crack front. The research will evaluate whether crack tunneling occurs and whether it consistently predicts a transition from cycle-dependent crack growth to time-dependent crack growth. The study is part of a larger research program trying to include the effects of geometry, mission profile and environmental effects, in addition to temperature effects, as a part of the overall crack growth system. The outcome will provide evidence for various transition types and correlate those physical attributes back to the material mechanisms to improve predictive modeling capability.

Mechanical Engineering Technology Curriculum.

ERIC Educational Resources Information Center

Georgia State Univ., Atlanta. Dept. of Vocational and Career Development.

This guide offers information and procedures necessary to train mechanical engineering technicians. Discussed first are the rationale and objectives of the curriculum. The occupational field of mechanical engineering technology is described. Next, a curriculum model is set forth that contains information on the standard mechanical engineering…

Antifriction basalt-plastics based on polypropylene

NASA Astrophysics Data System (ADS)

Bashtannik, P. I.; Ovcharenko, V. G.

1997-05-01

A study is made of the dependence of the mechanical and friction-engineering properties of polypropylene reinforced with basalt fibers on the viscosity of the polymer matrix. It is established that the main factors that determine the mechanical properties of the plastics are the quality of impregnation of the fibers by the binder and the residual length of the reinforcing filler in the composite after extrusion and injection molding. The material that was developed has a low friction coefficient and low rate of wear within a relatively brood range of friction conditions. The basalt-plastics can be used in the rubbing parts of machines and mechanisms subjected to dry friction.

Rocket engine injectorhead with flashback barrier

NASA Technical Reports Server (NTRS)

Mungas, Gregory S. (Inventor); Fisher, David J. (Inventor); Mungas, Christopher (Inventor)

2012-01-01

Propellants flow through specialized mechanical hardware that is designed for effective and safe ignition and sustained combustion of the propellants. By integrating a micro-fluidic porous media element between a propellant feed source and the combustion chamber, an effective and reliable propellant injector head may be implemented that is capable of withstanding transient combustion and detonation waves that commonly occur during an ignition event. The micro-fluidic porous media element is of specified porosity or porosity gradient selected to be appropriate for a given propellant. Additionally the propellant injector head design integrates a spark ignition mechanism that withstands extremely hot running conditions without noticeable spark mechanism degradation.

Molecular Engineering for Mechanically Resilient and Stretchable Electronic Polymers and Composites

DTIC Science & Technology

2016-06-08

AFRL-AFOSR-VA-TR-2016-0231 Molecular Engineering for Mechanically Resilient and Stretchable Electronic Polymers and Composites Darren Lipomi...04-2013 to 31-03-2016 4. TITLE AND SUBTITLE Molecular Engineering for Mechanically Resilient and Stretchable Electronic Polymers and Composites 5a... Engineering for Mechanically Resilient and Stretchable Electronic Polymers and Composites PI: Prof. Darren J. Lipomi 9500 Gilman Dr., Mail Code #0448

Novel perspectives for the engineering of abiotic stress tolerance in plants.

PubMed

Cabello, Julieta V; Lodeyro, Anabella F; Zurbriggen, Matias D

2014-04-01

Adverse environmental conditions pose serious limitations to agricultural production. Classical biotechnological approaches towards increasing abiotic stress tolerance focus on boosting plant endogenous defence mechanisms. However, overexpression of regulatory elements or effectors is usually accompanied by growth handicap and yield penalties due to crosstalk between developmental and stress-response networks. Herein we offer an overview on novel strategies with the potential to overcome these limitations based on the engineering of regulatory systems involved in the fine-tuning of the plant response to environmental hardships, including post-translational modifications, small RNAs, epigenetic control of gene expression and hormonal networks. The development and application of plant synthetic biology tools and approaches will add new functionalities and perspectives to genetic engineering programs for enhancing abiotic stress tolerance. Copyright © 2013 Elsevier Ltd. All rights reserved.

Modeling the Effects of Ice Accretion on the Low Pressure Compressor and the Overall Turbofan Engine System Performance

NASA Technical Reports Server (NTRS)

Veres, Joseph P.; Jorgenson, Philip C. E.; Wright, William B.

2011-01-01

The focus of this study is on utilizing a mean line compressor flow analysis code coupled to an engine system thermodynamic code, to estimate the effects of ice accretion on the low pressure compressor, and quantifying its effects on the engine system throughout a notional flight trajectory. In this paper a temperature range in which engine icing would occur was assumed. This provided a mechanism to locate potential component icing sites and allow the computational tools to add blockages due to ice accretion in a parametric fashion. Ultimately the location and level of blockage due to icing would be provided by an ice accretion code. To proceed, an engine system modeling code and a mean line compressor flow analysis code were utilized to calculate the flow conditions in the fan-core and low pressure compressor and to identify potential locations within the compressor where ice may accrete. In this study, an "additional blockage" due to the accretion of ice on the metal surfaces, has been added to the baseline aerodynamic blockage due to boundary layer, as well as the blade metal blockage. Once the potential locations of ice accretion are identified, the levels of additional blockage due to accretion were parametrically varied to estimate the effects on the low pressure compressor blade row performance operating within the engine system environment. This study includes detailed analysis of compressor and engine performance during cruise and descent operating conditions at several altitudes within the notional flight trajectory. The purpose of this effort is to develop the computer codes to provide a predictive capability to forecast the onset of engine icing events, such that they could ultimately help in the avoidance of these events.

Einstein-Podolsky-Rosen steering and Bell nonlocality of two macroscopic mechanical oscillators in optomechanical systems

NASA Astrophysics Data System (ADS)

Li, Jie; Zhu, Shi-Yao

2017-12-01

We investigate under which conditions quantum nonlocal manifestations such as Einstein-Podolsky-Rosen steering or Bell nonlocality can manifest themselves even at the macroscopic level of two mechanical resonators in optomechanical systems. We adopt the powerful scheme of reservoir engineering, implemented by driving a cavity mode with a properly chosen two-tone field, to prepare two mechanical oscillators in an entangled state. We show that large and robust (both one-way and two-way) steering could be achieved in the steady state with realistic parameters. We analyze the mechanism of the asymmetric nature of steering in our system of a two-mode Gaussian state. However, unlike steering, a Bell nonlocality is present under much more stringent conditions. We consider two types of measurements, displaced parity and on-off detection, respectively. We show that for both the measurements the Bell violation requires very low environmental temperature. For the parity detection, a large Bell violation is observed only in the transient state when the mechanical modes decouple from the optical mode and with extremely small cavity losses and mechanical damping. However, for the on-off detection, a moderate Bell violation is found in the steady state and is robust against cavity losses and mechanical damping. Although a Bell violation with parity detection seems extremely challenging to demonstrate experimentally, the conditions required for violating Bell inequalities with the on-off detection are much less demanding.

High speed turboprop aeroacoustic study (counterrotation). Volume 2: Computer programs

NASA Technical Reports Server (NTRS)

Whitfield, C. E.; Mani, R.; Gliebe, P. R.

1990-01-01

The isolated counterrotating high speed turboprop noise prediction program developed and funded by GE Aircraft Engines was compared with model data taken in the GE Aircraft Engines Cell 41 anechoic facility, the Boeing Transonic Wind Tunnel, and in the NASA-Lewis 8 x 6 and 9 x 15 wind tunnels. The predictions show good agreement with measured data under both low and high speed simulated flight conditions. The installation effect model developed for single rotation, high speed turboprops was extended to include counter rotation. The additional effect of mounting a pylon upstream of the forward rotor was included in the flow field modeling. A nontraditional mechanism concerning the acoustic radiation from a propeller at angle of attack was investigated. Predictions made using this approach show results that are in much closer agreement with measurement over a range of operating conditions than those obtained via traditional fluctuating force methods. The isolated rotors and installation effects models were combined into a single prediction program. The results were compared with data taken during the flight test of the B727/UDF (trademark) engine demonstrator aircraft.

High speed turboprop aeroacoustic study (counterrotation). Volume 2: Computer programs

NASA Astrophysics Data System (ADS)

Whitfield, C. E.; Mani, R.; Gliebe, P. R.

1990-07-01

The isolated counterrotating high speed turboprop noise prediction program developed and funded by GE Aircraft Engines was compared with model data taken in the GE Aircraft Engines Cell 41 anechoic facility, the Boeing Transonic Wind Tunnel, and in the NASA-Lewis 8 x 6 and 9 x 15 wind tunnels. The predictions show good agreement with measured data under both low and high speed simulated flight conditions. The installation effect model developed for single rotation, high speed turboprops was extended to include counter rotation. The additional effect of mounting a pylon upstream of the forward rotor was included in the flow field modeling. A nontraditional mechanism concerning the acoustic radiation from a propeller at angle of attack was investigated. Predictions made using this approach show results that are in much closer agreement with measurement over a range of operating conditions than those obtained via traditional fluctuating force methods. The isolated rotors and installation effects models were combined into a single prediction program. The results were compared with data taken during the flight test of the B727/UDF (trademark) engine demonstrator aircraft.

High-frequency ultrasonic imaging of growth and development in manufactured engineered oral mucosal tissue surfaces.

PubMed

Winterroth, Frank; Kato, Hiroko; Kuo, Shiuhyang; Feinberg, Stephen E; Hollister, Scott J; Fowlkes, J Brian; Hollman, Kyle W

2014-09-01

This study uses high-resolution ultrasound to examine the growth and development of engineered oral mucosal tissues manufactured under aseptic conditions. The specimens are a commercially available natural tissue scaffold, AlloDerm, and oral keratinocytes seeded onto AlloDerm to form an ex vivo-produced oral mucosal equivalent (EVPOME) suitable for intra-oral grafting. The seeded cells produce a keratinized protective upper layer that smooths out any remaining surface irregularities on the underlying AlloDerm. Two-dimensional acoustic imaging of unseeded AlloDerm and developing EVPOMEs was performed on each day of their growth and development, each tissue specimen being imaged under aseptic conditions (total time from seeding to maturation: 11 d). Ultrasonic monitoring offers us the ability to determine the constituents of the EVPOME that are responsible for changes in its mechanical behavior during the manufacturing process. Ultrasonic monitoring affords us an opportunity to non-invasively assess, in real time, tissue-engineered constructs before release for use in patient care. Copyright © 2014 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

Development and Testing of Ceramic Thermal Barrier Coatings

NASA Technical Reports Server (NTRS)

Zhu, Dongming; Choi, Sung R.; Miller, Robert A.

2004-01-01

Ceramic thermal barrier coatings will play an increasingly important role in future gas turbine engines because of their ability to effectively protect the engine components and further raise engine temperatures. Durability of the coating systems remains a critical issue with the ever-increasing temperature requirements. Thermal conductivity increase and coating degradation due to sintering and phase changes are known to be detrimental to coating performance. There is a need to characterize the coating behavior and temperature limits, in order to potentially take full advantage of the current coating capability, and also accurately assess the benefit gained from advanced coating development. In this study, thermal conductivity behavior and cyclic durability of plasma-sprayed ZrO2-8wt%Y2O3 thermal barrier coatings were evaluated under laser heat-flux simulated high temperature, large thermal gradient and thermal cycling conditions. The coating degradation and failure processes were assessed by real-time monitoring of the coating thermal conductivity under the test conditions. The ceramic coating crack propagation driving forces and resulting failure modes will be discussed in light of high temperature mechanical fatigue and fracture testing results.

Development and Fatigue Testing of Ceramic Thermal Barrier Coatings

NASA Technical Reports Server (NTRS)

Zhu, Dong-Ming; Choi, Sung R.; Miller, Robert A.

2004-01-01

Ceramic thermal barrier coatings will play an increasingly important role in future gas turbine engines because of their ability to effectively protect the engine components and further raise engine temperatures. Durability of the coating systems remains a critical issue with the ever-increasing temperature requirements. Thermal conductivity increase and coating degradation due to sintering and phase changes are known to be detrimental to coating performance. There is a need to characterize the coating thermal fatigue behavior and temperature limit, in order to potentially take full advantage of the current coating capability. In this study, thermal conductivity and cyclic fatigue behaviors of plasma-sprayed ZrO2-8wt%Y2O3 thermal barrier coatings were evaluated under high temperature, large thermal gradient and thermal cycling conditions. The coating degradation and failure processes were assessed by real-time monitoring of the coating thermal conductivity under the test conditions. The ceramic coating crack initiation and propagation driving forces and failure modes under the cyclic thermal loads will be discussed in light of the high temperature mechanical fatigue and fracture testing results.

Tissue Engineering Approaches in the Design of Healthy and Pathological In Vitro Tissue Models

PubMed Central

Caddeo, Silvia; Boffito, Monica; Sartori, Susanna

2017-01-01

In the tissue engineering (TE) paradigm, engineering and life sciences tools are combined to develop bioartificial substitutes for organs and tissues, which can in turn be applied in regenerative medicine, pharmaceutical, diagnostic, and basic research to elucidate fundamental aspects of cell functions in vivo or to identify mechanisms involved in aging processes and disease onset and progression. The complex three-dimensional (3D) microenvironment in which cells are organized in vivo allows the interaction between different cell types and between cells and the extracellular matrix, the composition of which varies as a function of the tissue, the degree of maturation, and health conditions. In this context, 3D in vitro models can more realistically reproduce a tissue or organ than two-dimensional (2D) models. Moreover, they can overcome the limitations of animal models and reduce the need for in vivo tests, according to the “3Rs” guiding principles for a more ethical research. The design of 3D engineered tissue models is currently in its development stage, showing high potential in overcoming the limitations of already available models. However, many issues are still opened, concerning the identification of the optimal scaffold-forming materials, cell source and biofabrication technology, and the best cell culture conditions (biochemical and physical cues) to finely replicate the native tissue and the surrounding environment. In the near future, 3D tissue-engineered models are expected to become useful tools in the preliminary testing and screening of drugs and therapies and in the investigation of the molecular mechanisms underpinning disease onset and progression. In this review, the application of TE principles to the design of in vitro 3D models will be surveyed, with a focus on the strengths and weaknesses of this emerging approach. In addition, a brief overview on the development of in vitro models of healthy and pathological bone, heart, pancreas, and liver will be presented. PMID:28798911

Tissue Engineering Approaches in the Design of Healthy and Pathological In Vitro Tissue Models.

PubMed

Caddeo, Silvia; Boffito, Monica; Sartori, Susanna

2017-01-01

In the tissue engineering (TE) paradigm, engineering and life sciences tools are combined to develop bioartificial substitutes for organs and tissues, which can in turn be applied in regenerative medicine, pharmaceutical, diagnostic, and basic research to elucidate fundamental aspects of cell functions in vivo or to identify mechanisms involved in aging processes and disease onset and progression. The complex three-dimensional (3D) microenvironment in which cells are organized in vivo allows the interaction between different cell types and between cells and the extracellular matrix, the composition of which varies as a function of the tissue, the degree of maturation, and health conditions. In this context, 3D in vitro models can more realistically reproduce a tissue or organ than two-dimensional (2D) models. Moreover, they can overcome the limitations of animal models and reduce the need for in vivo tests, according to the "3Rs" guiding principles for a more ethical research. The design of 3D engineered tissue models is currently in its development stage, showing high potential in overcoming the limitations of already available models. However, many issues are still opened, concerning the identification of the optimal scaffold-forming materials, cell source and biofabrication technology, and the best cell culture conditions (biochemical and physical cues) to finely replicate the native tissue and the surrounding environment. In the near future, 3D tissue-engineered models are expected to become useful tools in the preliminary testing and screening of drugs and therapies and in the investigation of the molecular mechanisms underpinning disease onset and progression. In this review, the application of TE principles to the design of in vitro 3D models will be surveyed, with a focus on the strengths and weaknesses of this emerging approach. In addition, a brief overview on the development of in vitro models of healthy and pathological bone, heart, pancreas, and liver will be presented.

Revolutionary Materials for Hypersonic Flight

DTIC Science & Technology

2011-10-01

Transactions A (in preparation ). 16. M.D. Novak, CG. Levi, " Silicide Coatings on Niobium Substrates II: Thermodynamic Analysis and Mechanism of...These conditions impose significant challenges to material selection. While metallic materials are favored for their durability to thermal distortion...those of even the most highly-conducting engineering materials. While metallic systems are desirable for use in hypersonic vehicles for durability and

Admissions Policies as a Mechanism for Social Engineering: The Case of the Bulgarian Communist Regime

ERIC Educational Resources Information Center

Boyadjieva, Pepka Alexandrova

2013-01-01

This article discusses admissions policies to higher education during the Communist regime in Bulgaria (1946-89). It argues that under the conditions of the Bulgarian Communist regime, admissions policies were not only a component of the higher education system--viewed as an institution--but part and parcel of the process through which power was…

Shelterwood-Strip Harvesting Pattern With Full-Tree Skidding to Regenerate Red Pine

Treesearch

John W. Benzie; Z.A. Zasada

1972-01-01

Describes a harvesting and regeneration pattern for red pine stands to make efficient use of mechanized full-tree harvesting. The system is not just an engineering operation to extract trees, but a forest management operatioin to harvest mature timber, prepare the site for regeneration, and provide environmental conditions favoring tree growth and multiple-use of the...

High speed turboprop aeroacoustic study (counterrotation). Volume 1: Model development

NASA Technical Reports Server (NTRS)

Whitfield, C. E.; Mani, R.; Gliebe, P. R.

1990-01-01

The isolated counterrotating high speed turboprop noise prediction program was compared with model data taken in the GE Aircraft Engines Cell 41 anechoic facility, the Boeing Transonic Wind Tunnel, and in NASA-Lewis' 8x6 and 9x15 wind tunnels. The predictions show good agreement with measured data under both low and high speed simulated flight conditions. The installation effect model developed for single rotation, high speed turboprops was extended to include counterotation. The additional effect of mounting a pylon upstream of the forward rotor was included in the flow field modeling. A nontraditional mechanism concerning the acoustic radiation from a propeller at angle of attach was investigated. Predictions made using this approach show results that are in much closer agreement with measurement over a range of operating conditions than those obtained via traditional fluctuating force methods. The isolated rotors and installation effects models were combines into a single prediction program, results of which were compared with data taken during the flight test of the B727/UDF engine demonstrator aircraft. Satisfactory comparisons between prediction and measured data for the demonstrator airplane, together with the identification of a nontraditional radiation mechanism for propellers at angle of attack are achieved.

High speed turboprop aeroacoustic study (counterrotation). Volume 1: Model development

NASA Astrophysics Data System (ADS)

Whitfield, C. E.; Mani, R.; Gliebe, P. R.

1990-07-01

The isolated counterrotating high speed turboprop noise prediction program was compared with model data taken in the GE Aircraft Engines Cell 41 anechoic facility, the Boeing Transonic Wind Tunnel, and in NASA-Lewis' 8x6 and 9x15 wind tunnels. The predictions show good agreement with measured data under both low and high speed simulated flight conditions. The installation effect model developed for single rotation, high speed turboprops was extended to include counterotation. The additional effect of mounting a pylon upstream of the forward rotor was included in the flow field modeling. A nontraditional mechanism concerning the acoustic radiation from a propeller at angle of attach was investigated. Predictions made using this approach show results that are in much closer agreement with measurement over a range of operating conditions than those obtained via traditional fluctuating force methods. The isolated rotors and installation effects models were combines into a single prediction program, results of which were compared with data taken during the flight test of the B727/UDF engine demonstrator aircraft. Satisfactory comparisons between prediction and measured data for the demonstrator airplane, together with the identification of a nontraditional radiation mechanism for propellers at angle of attack are achieved.

Mechanics of Granular Materials (MGM0 Flight Hardware in Bench Test

NASA Technical Reports Server (NTRS)

2000-01-01

Engineering bench system hardware for the Mechanics of Granular Materials (MGM) experiment is tested on a lab bench at the University of Colorado in Boulder. This is done in a horizontal arrangement to reduce pressure differences so the tests more closely resemble behavior in the microgravity of space. Sand and soil grains have faces that can cause friction as they roll and slide against each other, or even cause sticking and form small voids between grains. This complex behavior can cause soil to behave like a liquid under certain conditions such as earthquakes or when powders are handled in industrial processes. MGM experiments aboard the Space Shuttle use the microgravity of space to simulate this behavior under conditions that carnot be achieved in laboratory tests on Earth. MGM is shedding light on the behavior of fine-grain materials under low effective stresses. Applications include earthquake engineering, granular flow technologies (such as powder feed systems for pharmaceuticals and fertilizers), and terrestrial and planetary geology. Nine MGM specimens have flown on two Space Shuttle flights. Another three are scheduled to fly on STS-107. The principal investigator is Stein Sture of the University of Colorado at Boulder. (Credit: University of Colorado at Boulder).

Relationship of trehalose accumulation with ethanol fermentation in industrial Saccharomyces cerevisiae yeast strains.

PubMed

Wang, Pin-Mei; Zheng, Dao-Qiong; Chi, Xiao-Qin; Li, Ou; Qian, Chao-Dong; Liu, Tian-Zhe; Zhang, Xiao-Yang; Du, Feng-Guang; Sun, Pei-Yong; Qu, Ai-Min; Wu, Xue-Chang

2014-01-01

The protective effect and the mechanisms of trehalose accumulation in industrial Saccharomyces cerevisiae strains were investigated during ethanol fermentation. The engineered strains with more intercellular trehalose achieved significantly higher fermentation rates and ethanol yields than their wild strain ZS during very high gravity (VHG) fermentation, while their performances were not different during regular fermentation. The VHG fermentation performances of these strains were consistent with their growth capacity under osmotic stress and ethanol stress, the key stress factors during VHG fermentation. These results suggest that trehalose accumulation is more important for VHG fermentation of industrial yeast strains than regular one. The differences in membrane integrity and antioxidative capacity of these strains indicated the possible mechanisms of trehalose as a protectant under VHG condition. Therefore, trehalose metabolic engineering may be a useful strategy for improving the VHG fermentation performance of industrial yeast strains. Copyright © 2013 Elsevier Ltd. All rights reserved.

Concurrently adjusting interrelated control parameters to achieve optimal engine performance

DOEpatents

Jiang, Li; Lee, Donghoon; Yilmaz, Hakan; Stefanopoulou, Anna

2015-12-01

Methods and systems for real-time engine control optimization are provided. A value of an engine performance variable is determined, a value of a first operating condition and a value of a second operating condition of a vehicle engine are detected, and initial values for a first engine control parameter and a second engine control parameter are determined based on the detected first operating condition and the detected second operating condition. The initial values for the first engine control parameter and the second engine control parameter are adjusted based on the determined value of the engine performance variable to cause the engine performance variable to approach a target engine performance variable. In order to cause the engine performance variable to approach the target engine performance variable, adjusting the initial value for the first engine control parameter necessitates a corresponding adjustment of the initial value for the second engine control parameter.

Advanced Turbine Technology Applications Project (ATTAP)

NASA Technical Reports Server (NTRS)

1990-01-01

Advanced Turbine Technology Application Project (ATTAP) activities during the past year were highlighted by test-bed engine design and development activities; ceramic component design; materials and component characterization; ceramic component process development and fabrication; component rig testing; and test-bed engine fabrication and testing. Although substantial technical challenges remain, all areas exhibited progress. Test-bed engine design and development activity included engine mechanical design, power turbine flow-path design and mechanical layout, and engine system integration aimed at upgrading the AGT-5 from a 1038 C metal engine to a durable 1371 C structural ceramic component test-bed engine. ATTAP-defined ceramic and associated ceramic/metal component design activities include: the ceramic combustor body, the ceramic gasifier turbine static structure, the ceramic gasifier turbine rotor, the ceramic/metal power turbine static structure, and the ceramic power turbine rotors. The materials and component characterization efforts included the testing and evaluation of several candidate ceramic materials and components being developed for use in the ATTAP. Ceramic component process development and fabrication activities are being conducted for the gasifier turbine rotor, gasifier turbine vanes, gasifier turbine scroll, extruded regenerator disks, and thermal insulation. Component rig testing activities include the development of the necessary test procedures and conduction of rig testing of the ceramic components and assemblies. Four-hundred hours of hot gasifier rig test time were accumulated with turbine inlet temperatures exceeding 1204 C at 100 percent design gasifier speed. A total of 348.6 test hours were achieved on a single ceramic rotor without failure and a second ceramic rotor was retired in engine-ready condition at 364.9 test hours. Test-bed engine fabrication, testing, and development supported improvements in ceramic component technology that will permit the achievement of program performance and durability goals. The designated durability engine accumulated 359.3 hour of test time, 226.9 of which were on the General Motors gas turbine durability schedule.

Assessment of Knowledge and Skills Needed in Selected Engineering Technician Fields: Mechanical/Manufacturing/Industrial.

ERIC Educational Resources Information Center

Gourley, Frank A., Jr.

A study identified the essential educational topics and the level of proficiency perceived to be required in these topics for selected two-year engineering technology programs in North Carolina. The four curricula studied were mechanical engineering technology, mechanical drafting and design technology, manufacturing engineering technology, and…

Development of Biodegradable Poly(citrate)-Polyhedral Oligomeric Silsesquioxanes Hybrid Elastomers with High Mechanical Properties and Osteogenic Differentiation Activity.

PubMed

Du, Yuzhang; Yu, Meng; Chen, Xiaofeng; Ma, Peter X; Lei, Bo

2016-02-10

Biodegradable elastomeric biomaterials have attracted much attention in tissue engineering due to their biomimetic viscoelastic behavior and biocompatibility. However, the low mechanical stability at hydrated state, fast biodegradation in vivo, and poor osteogenic activity greatly limited bioelastomers applications in bone tissue regeneration. Herein, we develop a series of poly(octanediol citrate)-polyhedral oligomeric silsesquioxanes (POC-POSS) hybrids with highly tunable elastomeric behavior (hydrated state) and biodegradation and osteoblasts biocompatibility through a facile one-pot thermal polymerization strategy. POC-POSS hybrids show significantly improved stiffness and ductility in either dry or hydrated conditions, as well as good antibiodegradation ability (20-50% weight loss in 3 months). POC-POSS hybrids exhibit significantly enhanced osteogenic differentiation through upregulating alkaline phosphatase (ALP) activity, calcium deposition, and expression of osteogenic markers (ALPL, BGLAP, and Runx2). The high mechanical stability at hydrated state and enhanced osteogenic activity make POC-POSS hybrid elastomers promising as scaffolds and nanoscale vehicles for bone tissue regeneration and drug delivery. This study may also provide a new strategy (controlling the stiffness under hydrated condition) to design advanced hybrid biomaterials with high mechanical properties under physiological condition for tissue regeneration applications.

Self Diagnostic Accelerometer for Mission Critical Health Monitoring of Aircraft and Spacecraft Engines

NASA Technical Reports Server (NTRS)

Lekki, John; Tokars, Roger; Jaros, Dave; Riggs, M. Terrence; Evans, Kenneth P.; Gyekenyesi, Andrew

2009-01-01

A self diagnostic accelerometer system has been shown to be sensitive to multiple failure modes of charge mode accelerometers. These failures include sensor structural damage, an electrical open circuit and most importantly sensor detachment. In this paper, experimental work that was performed to determine the capabilities of a self diagnostic accelerometer system while operating in the presence of various levels of mechanical noise, emulating real world conditions, is presented. The results show that the system can successfully conduct a self diagnostic routine under these conditions.

Correction of engineering servicing regularity of transporttechnological machines in operational process

NASA Astrophysics Data System (ADS)

Makarova, A. N.; Makarov, E. I.; Zakharov, N. S.

2018-03-01

In the article, the issue of correcting engineering servicing regularity on the basis of actual dependability data of cars in operation is considered. The purpose of the conducted research is to increase dependability of transport-technological machines by correcting engineering servicing regularity. The subject of the research is the mechanism of engineering servicing regularity influence on reliability measure. On the basis of the analysis of researches carried out before, a method of nonparametric estimation of car failure measure according to actual time-to-failure data was chosen. A possibility of describing the failure measure dependence on engineering servicing regularity by various mathematical models is considered. It is proven that the exponential model is the most appropriate for that purpose. The obtained results can be used as a separate method of engineering servicing regularity correction with certain operational conditions taken into account, as well as for the technical-economical and economical-stochastic methods improvement. Thus, on the basis of the conducted researches, a method of engineering servicing regularity correction of transport-technological machines in the operational process was developed. The use of that method will allow decreasing the number of failures.

Performance deterioration based on existing (historical) data; JT9D jet engine diagnostics program

NASA Technical Reports Server (NTRS)

Sallee, G. P.

1978-01-01

The results of the collection and analysis of historical data pertaining to the deterioration of JT9D engine performance are presented. The results of analyses of prerepair and postrepair engine test stand performance data from a number of airlines to establish the individual as well as average losses in engine performance with respect to service use are included. Analysis of the changes in mechanical condition of parts, obtained by inspection of used gas-path parts of varying age, allowed preliminary assessments of component performance deterioration levels and identification of the causitive factors. These component performance estimates, refined by data from special engine back-to-back testing related to module performance restoration, permitted the development of preliminary models of engine component/module performance deterioration with respect to usage. The preliminary assessment of the causes of module performance deterioration and the trends with usage are explained, along with the role each module plays in overall engine performance deterioration. Preliminary recommendations with respect to operating and maintenance practices which could be adopted to control the level of performance deterioration are presented. The needs for additional component sensitivity testing as well as outstanding issues are discussed.

Behavioural system identification of visual flight speed control in Drosophila melanogaster

PubMed Central

Rohrseitz, Nicola; Fry, Steven N.

2011-01-01

Behavioural control in many animals involves complex mechanisms with intricate sensory-motor feedback loops. Modelling allows functional aspects to be captured without relying on a description of the underlying complex, and often unknown, mechanisms. A wide range of engineering techniques are available for modelling, but their ability to describe time-continuous processes is rarely exploited to describe sensory-motor control mechanisms in biological systems. We performed a system identification of visual flight speed control in the fruitfly Drosophila, based on an extensive dataset of open-loop responses previously measured under free flight conditions. We identified a second-order under-damped control model with just six free parameters that well describes both the transient and steady-state characteristics of the open-loop data. We then used the identified control model to predict flight speed responses after a visual perturbation under closed-loop conditions and validated the model with behavioural measurements performed in free-flying flies under the same closed-loop conditions. Our system identification of the fruitfly's flight speed response uncovers the high-level control strategy of a fundamental flight control reflex without depending on assumptions about the underlying physiological mechanisms. The results are relevant for future investigations of the underlying neuromotor processing mechanisms, as well as for the design of biomimetic robots, such as micro-air vehicles. PMID:20525744

Behavioural system identification of visual flight speed control in Drosophila melanogaster.

PubMed

Rohrseitz, Nicola; Fry, Steven N

2011-02-06

Behavioural control in many animals involves complex mechanisms with intricate sensory-motor feedback loops. Modelling allows functional aspects to be captured without relying on a description of the underlying complex, and often unknown, mechanisms. A wide range of engineering techniques are available for modelling, but their ability to describe time-continuous processes is rarely exploited to describe sensory-motor control mechanisms in biological systems. We performed a system identification of visual flight speed control in the fruitfly Drosophila, based on an extensive dataset of open-loop responses previously measured under free flight conditions. We identified a second-order under-damped control model with just six free parameters that well describes both the transient and steady-state characteristics of the open-loop data. We then used the identified control model to predict flight speed responses after a visual perturbation under closed-loop conditions and validated the model with behavioural measurements performed in free-flying flies under the same closed-loop conditions. Our system identification of the fruitfly's flight speed response uncovers the high-level control strategy of a fundamental flight control reflex without depending on assumptions about the underlying physiological mechanisms. The results are relevant for future investigations of the underlying neuromotor processing mechanisms, as well as for the design of biomimetic robots, such as micro-air vehicles.

Bioreactor Technology in Cardiovascular Tissue Engineering

NASA Astrophysics Data System (ADS)

Mertsching, H.; Hansmann, J.

Cardiovascular tissue engineering is a fast evolving field of biomedical science and technology to manufacture viable blood vessels, heart valves, myocar-dial substitutes and vascularised complex tissues. In consideration of the specific role of the haemodynamics of human circulation, bioreactors are a fundamental of this field. The development of perfusion bioreactor technology is a consequence of successes in extracorporeal circulation techniques, to provide an in vitro environment mimicking in vivo conditions. The bioreactor system should enable an automatic hydrodynamic regime control. Furthermore, the systematic studies regarding the cellular responses to various mechanical and biochemical cues guarantee the viability, bio-monitoring, testing, storage and transportation of the growing tissue.

Molten salt corrosion of SiC and Si3N4

NASA Technical Reports Server (NTRS)

Jacobson, N. S.; Smialek, J. L.; Fox, D. S.

1986-01-01

The most severe type of corrosion encountered in heat engines is corrosion by molten sodium sulfate, formed by the reaction of ingested sodium chloride and sulfur impurities in the fuel. This problem was studied extensively for superalloys, but only recently examined for ceramics. This problem is addressed with laboratory studies to understand the fundamental reaction mechanisms and with burner studies to provide a more realistic simulation of the conditions encountered in a heat engine. In addition the effect of corrosion on the strengths of these materials was assessed. Each of these aspects will be reviewed and some ideas toward possible solutions will be discussed.

Damage-mitigating control of space propulsion systems for high performance and extended life

NASA Technical Reports Server (NTRS)

Ray, Asok; Wu, Min-Kuang; Dai, Xiaowen; Carpino, Marc; Lorenzo, Carl F.

1993-01-01

Calculations are presented showing that a substantial improvement in service life of a reusable rocket engine can be achieved by an insignificant reduction in the system dynamic performance. The paper introduces the concept of damage mitigation and formulates a continuous-time model of fatigue damage dynamics. For control of complex mechanical systems, damage prediction and damage mitigation are carried out based on the available sensory and operational information such that the plant can be inexpensively maintained and safely and efficiently steered under diverse operating conditions. The results of simulation experiments are presented for transient operations of a reusable rocket engine.

Winglet effects on the flutter of twin-engine-transport type wing

NASA Technical Reports Server (NTRS)

Bhatia, K. G.; Nagaraja, K. S.; Ruhlin, C. L.

1984-01-01

Flutter characteristics of a cantilevered high aspect ratio wing with winglet were investigated. The configuration represented a current technology, twin-engine airplane. A low-speed and a high-speed model were used to evaluate compressibility effects through transonic Mach numbers and a wide range of mass-density ratios. Four flutter mechanisms were obtained in test, as well as analysis from various combinations of configuration parameters. The coupling between wing tip vertical and chordwise motions was shown to have significant effect under some conditions. It is concluded that, for the flutter model configurations studied, the winglet related flutter was amenable to the conventional flutter analysis techniques.

Advanced Environmental Barrier Coating Development for SiC-SiC Ceramic Matrix Composite Components

NASA Technical Reports Server (NTRS)

Zhu, Dongming; Harder, Bryan; Bhatt, Ramakrishna; Kiser, Doug; Wiesner, Valerie L.

2016-01-01

This presentation reviews the NASA advanced environmental barrier coating (EBC) system development for SiCSiC Ceramic Matrix Composite (CMC) components for next generation turbine engines. The emphasis has been placed on the current design challenges of the 2700F environmental barrier coatings; coating processing and integration with SiCSiC CMCs and component systems; and performance evaluation and demonstration of EBC-CMC systems. This presentation also highlights the EBC-CMC system temperature capability and durability improvements through advanced compositions and architecture designs, as shown in recent simulated engine high heat flux, combustion environment, in conjunction with mechanical creep and fatigue loading testing conditions.

78 FR 37721 - Approval of American Society of Mechanical Engineers' Code Cases

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-24

...-0359] RIN 3150-AI72 Approval of American Society of Mechanical Engineers' Code Cases AGENCY: Nuclear... mandatory American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel (BPV) Code and... Guide'' series. In a notice of proposed rulemaking, ``Approval of American Society of Mechanical...

Small Engines and Outboard Marine Mechanics Curriculum.

ERIC Educational Resources Information Center

Alaska State Dept. of Education, Juneau. Div. of Adult and Vocational Education.

This competency-based curriculum guide is a handbook for the development of small engine and outboard marine mechanics programs. Based on a survey of Alaskan small engines and marine mechanics employers, it includes all competencies a student should acquire in such a mechanics program. The handbook stresses the importance of understanding the…

Influence of culture conditions and extracellular matrix alignment on human mesenchymal stem cells invasion into decellularized engineered tissues.

PubMed

Weidenhamer, Nathan K; Moore, Dusty L; Lobo, Fluvio L; Klair, Nathaniel T; Tranquillo, Robert T

2015-05-01

The variables that influence the in vitro recellularization potential of decellularized engineered tissues, such as cell culture conditions and scaffold alignment, have yet to be explored. The goal of this work was to explore the influence of insulin and ascorbic acid and extracellular matrix (ECM) alignment on the recellularization of decellularized engineered tissue by human mesenchymal stem cells (hMSCs). Aligned and non-aligned tissues were created by specifying the geometry and associated mechanical constraints to fibroblast-mediated fibrin gel contraction and remodelling using circular and C-shaped moulds. Decellularized tissues (matrices) of the same alignment were created by decellularization with detergents. Ascorbic acid promoted the invasion of hMSCs into the matrices due to a stimulated increase in motility and proliferation. Invasion correlated with hyaluronic acid secretion, α-smooth muscle actin expression and decreased matrix thickness. Furthermore, hMSCs invasion into aligned and non-aligned matrices was not different, although there was a difference in cell orientation. Finally, we show that hMSCs on the matrix surface appear to differentiate toward a smooth muscle cell or myofibroblast phenotype with ascorbic acid treatment. These results inform the strategy of recellularizing decellularized engineered tissue with hMSCs. Copyright © 2014 John Wiley & Sons, Ltd.

Fibrocartilage tissue engineering: the role of the stress environment on cell morphology and matrix expression.

PubMed

Thomopoulos, Stavros; Das, Rosalina; Birman, Victor; Smith, Lester; Ku, Katherine; Elson, Elliott L; Pryse, Kenneth M; Marquez, Juan Pablo; Genin, Guy M

2011-04-01

Although much is known about the effects of uniaxial mechanical loading on fibrocartilage development, the stress fields to which fibrocartilaginous regions are subjected to during development are mutiaxial. That fibrocartilage develops at tendon-to-bone attachments and in compressive regions of tendons is well established. However, the three-dimensional (3D) nature of the stresses needed for the development of fibrocartilage is not known. Here, we developed and applied an in vitro system to determine whether fibrocartilage can develop under a state of periodic hydrostatic tension in which only a single principal component of stress is compressive. This question is vital to efforts to mechanically guide morphogenesis and matrix expression in engineered tissue replacements. Mesenchymal stromal cells in a 3D culture were exposed to compressive and tensile stresses as a result of an external tensile hydrostatic stress field. The stress field was characterized through mechanical modeling. Tensile cyclic stresses promoted spindle-shaped cells, upregulation of scleraxis and type one collagen, and cell alignment with the direction of tension. Cells experiencing a single compressive stress component exhibited rounded cell morphology and random cell orientation. No difference in mRNA expression of the genes Sox9 and aggrecan was observed when comparing tensile and compressive regions unless the medium was supplemented with the chondrogenic factor transforming growth factor beta3. In that case, Sox9 was upregulated under static loading conditions and aggrecan was upregulated under cyclic loading conditions. In conclusion, the fibrous component of fibrocartilage could be generated using only mechanical cues, but generation of the cartilaginous component of fibrocartilage required biologic factors in addition to mechanical cues. These studies support the hypothesis that the 3D stress environment influences cell activity and gene expression in fibrocartilage development.

Fibrocartilage Tissue Engineering: The Role of the Stress Environment on Cell Morphology and Matrix Expression

PubMed Central

Das, Rosalina; Birman, Victor; Smith, Lester; Ku, Katherine; Elson, Elliott L.; Pryse, Kenneth M.; Marquez, Juan Pablo; Genin, Guy M.

2011-01-01

Although much is known about the effects of uniaxial mechanical loading on fibrocartilage development, the stress fields to which fibrocartilaginous regions are subjected to during development are mutiaxial. That fibrocartilage develops at tendon-to-bone attachments and in compressive regions of tendons is well established. However, the three-dimensional (3D) nature of the stresses needed for the development of fibrocartilage is not known. Here, we developed and applied an in vitro system to determine whether fibrocartilage can develop under a state of periodic hydrostatic tension in which only a single principal component of stress is compressive. This question is vital to efforts to mechanically guide morphogenesis and matrix expression in engineered tissue replacements. Mesenchymal stromal cells in a 3D culture were exposed to compressive and tensile stresses as a result of an external tensile hydrostatic stress field. The stress field was characterized through mechanical modeling. Tensile cyclic stresses promoted spindle-shaped cells, upregulation of scleraxis and type one collagen, and cell alignment with the direction of tension. Cells experiencing a single compressive stress component exhibited rounded cell morphology and random cell orientation. No difference in mRNA expression of the genes Sox9 and aggrecan was observed when comparing tensile and compressive regions unless the medium was supplemented with the chondrogenic factor transforming growth factor beta3. In that case, Sox9 was upregulated under static loading conditions and aggrecan was upregulated under cyclic loading conditions. In conclusion, the fibrous component of fibrocartilage could be generated using only mechanical cues, but generation of the cartilaginous component of fibrocartilage required biologic factors in addition to mechanical cues. These studies support the hypothesis that the 3D stress environment influences cell activity and gene expression in fibrocartilage development. PMID:21091338

Working fluid selection for the Organic Rankine Cycle (ORC) exhaust heat recovery of an internal combustion engine power plant

NASA Astrophysics Data System (ADS)

Douvartzides, S.; Karmalis, I.

2016-11-01

Organic Rankine cycle technology is capable to efficiently convert low-grade heat into useful mechanical power. In the present investigation such a cycle is used for the recovery of heat from the exhaust gases of a four stroke V18 MAN 51/60DF internal combustion engine power plant operating with natural gas. Design is focused on the selection of the appropriate working fluid of the Rankine cycle in terms of thermodynamic, environmental and safety criteria. 37 candidate fluids have been considered and all Rankine cycles examined were subcritical. The thermodynamic analysis of all fluids has been comparatively undertaken and the effect of key operation conditions such as the evaporation pressure and the superheating temperature was taken into account. By appropriately selecting the working fluid and the Rankine cycle operation conditions the overall plant efficiency was improved by 5.52% and fuel consumption was reduced by 12.69%.

Experimental Study of Injection Characteristics of a Multi-hole port injector on various Fuel Injection pressures and Temperatures

NASA Astrophysics Data System (ADS)

Movahednejad, E.; Ommi, F.; Nekofar, K.

2013-04-01

The structures of the port injector spray dominates the mixture preparation process and strongly affect the subsequent engine combustion characteristics over a wide range of operating conditions in port-injection gasoline engines. All these spray characteristics are determined by particular injector design and operating conditions. In this paper, an experimental study is made to characterize the breakup mechanism and spray characteristics of a injector with multi-disc nozzle (SAGEM,D2159MA). A comparison was made on injection characteristics of the multi-hole injectors and its effects on various fuel pressure and temperature. The distributions of the droplet size and velocity and volume flux were characterized using phase Doppler anemometry (PDA) technique. Through this work, it was found that the injector produces a finer spray with a wide spray angle in higher fuel pressure and temperature.

Evidence of Facilitation Cascade Processes as Drivers of Successional Patterns of Ecosystem Engineers at the Upper Altitudinal Limit of the Dry Puna

PubMed Central

2016-01-01

Facilitation processes constitute basic elements of vegetation dynamics in harsh systems. Recent studies in tropical alpine environments demonstrated how pioneer plant species defined as “ecosystem engineers” are capable of enhancing landscape-level richness by adding new species to the community through the modification of microhabitats, and also provided hints about the alternation of different ecosystem engineers over time. Nevertheless, most of the existing works analysed different ecosystem engineers separately, without considering the interaction of different ecosystem engineers. Focusing on the altitudinal limit of Peruvian Dry Puna vegetation, we hypothesized that positive interactions structure plant communities by facilitation cascades involving different ecosystem engineers, determining the evolution of the microhabitat patches in terms of abiotic resources and beneficiary species hosted. To analyze successional mechanisms, we used a “space-for-time” substitution to account for changes over time, and analyzed data on soil texture, composition, and temperature, facilitated species and their interaction with nurse species, and surface area of engineered patches by means of chemical analyses, indicator species analysis, and rarefaction curves. A successional process, resulting from the dynamic interaction of different ecosystem engineers, which determined a progressive amelioration of soil conditions (e.g. nitrogen and organic matter content, and temperature), was the main driver of species assemblage at the community scale, enhancing species richness. Cushion plants act as pioneers, by starting the successional processes that continue with shrubs and tussocks. Tussock grasses have sometimes been found to be capable of creating microhabitat patches independently. The dynamics of species assemblage seem to follow the nested assemblage mechanism, in which the first foundation species to colonize a habitat provides a novel substrate for colonization by other foundation species through a facilitation cascade process. PMID:27902757

Integrative Utilization of Microenvironments, Biomaterials and Computational Techniques for Advanced Tissue Engineering.

PubMed

Shamloo, Amir; Mohammadaliha, Negar; Mohseni, Mina

2015-10-20

This review aims to propose the integrative implementation of microfluidic devices, biomaterials, and computational methods that can lead to a significant progress in tissue engineering and regenerative medicine researches. Simultaneous implementation of multiple techniques can be very helpful in addressing biological processes. Providing controllable biochemical and biomechanical cues within artificial extracellular matrix similar to in vivo conditions is crucial in tissue engineering and regenerative medicine researches. Microfluidic devices provide precise spatial and temporal control over cell microenvironment. Moreover, generation of accurate and controllable spatial and temporal gradients of biochemical factors is attainable inside microdevices. Since biomaterials with tunable properties are a worthwhile option to construct artificial extracellular matrix, in vitro platforms that simultaneously utilize natural, synthetic, or engineered biomaterials inside microfluidic devices are phenomenally advantageous to experimental studies in the field of tissue engineering. Additionally, collaboration between experimental and computational methods is a useful way to predict and understand mechanisms responsible for complex biological phenomena. Computational results can be verified by using experimental platforms. Computational methods can also broaden the understanding of the mechanisms behind the biological phenomena observed during experiments. Furthermore, computational methods are powerful tools to optimize the fabrication of microfluidic devices and biomaterials with specific features. Here we present a succinct review of the benefits of microfluidic devices, biomaterial, and computational methods in the case of tissue engineering and regeneration medicine. Furthermore, some breakthroughs in biological phenomena including the neuronal axon development, cancerous cell migration and blood vessel formation via angiogenesis by virtue of the aforementioned approaches are discussed. Copyright © 2015 Elsevier B.V. All rights reserved.

40 CFR 1065.410 - Maintenance limits for stabilized test engines.

Code of Federal Regulations, 2013 CFR

2013-07-01

... engineering grade tools to identify bad engine components. Any equipment, instruments, or tools used for... no longer use it as an emission-data engine. Also, if your test engine has a major mechanical failure... your test engine has a major mechanical failure that requires you to take it apart, you may no longer...

40 CFR 1065.410 - Maintenance limits for stabilized test engines.

Code of Federal Regulations, 2012 CFR

2012-07-01

... engineering grade tools to identify bad engine components. Any equipment, instruments, or tools used for... no longer use it as an emission-data engine. Also, if your test engine has a major mechanical failure... your test engine has a major mechanical failure that requires you to take it apart, you may no longer...

The Institute of Biological Engineering 2013 Annual Conference

DTIC Science & Technology

2014-10-30

of Bioengineering University of Washington Presentation: Peptide-Based materials for Drug Delivery Dr. Ya-Ping Sun (Supported by the Grant) Frank...Professor of Biomedical Engineering and Mechanical Engineering and Materials Science Duke University Presentation: Acoustic Microfluidics and New...Triangle Materials Research Science and Engineering Center, Department of Biomedical Engineering, Duke University, Department of Mechanical Engineering

Mechanical Engineering | Classification | College of Engineering & Applied

Science.gov Websites

ProfessorMechanical Engineering(414) 229-6949avdeev@uwm.eduEng & Math Sciences 975 profile photo Robert Balmer, Sc . D.Professor EmeritusMechanical Engineering(414) 229-3374balmer@uwm.eduEng & Math Sciences E260 profile -6614wjchang@uwm.eduEng & Math Sciences 1113 profile photo Junhong Chen Ph.D.UWM Distinguished

Engineering a Place for Women: A Study of How Departmental Climate Influences the Career Satisfaction of Female Mechanical Engineering Faculty Members

ERIC Educational Resources Information Center

Young, Monica J.

2012-01-01

The purpose of this mixed-methods study was to better understand how female mechanical engineering faculty members' career experiences in academia affect their satisfaction. Specifically, the research considered differences in satisfaction reported by female and male mechanical engineering faculty members in terms of: (a) departmental…

Integrating Communication into Engineering Curricula: An Interdisciplinary Approach to Facilitating Transfer at New Mexico Institute of Mining and Technology

ERIC Educational Resources Information Center

Ford, Julie Dyke

2012-01-01

This program profile describes a new approach towards integrating communication within Mechanical Engineering curricula. The author, who holds a joint appointment between Technical Communication and Mechanical Engineering at New Mexico Institute of Mining and Technology, has been collaborating with Mechanical Engineering colleagues to establish a…

Identification of Bearing Failure Using Signal Vibrations

NASA Astrophysics Data System (ADS)

Yani, Irsyadi; Resti, Yulia; Burlian, Firmansyah

2018-04-01

Vibration analysis can be used to identify damage to mechanical systems such as journal bearings. Identification of failure can be done by observing the resulting vibration spectrum by measuring the vibration signal occurring in a mechanical system Bearing is one of the engine elements commonly used in mechanical systems. The main purpose of this research is to monitor the bearing condition and to identify bearing failure on a mechanical system by observing the resulting vibration. Data collection techniques based on recordings of sound caused by the vibration of the mechanical system were used in this study, then created a database system based bearing failure due to vibration signal recording sounds on a mechanical system The next step is to group the bearing damage by type based on the databases obtained. The results show the percentage of success in identifying bearing damage is 98 %.

Minimum Specific Fuel Consumption of a Liquid-Cooled Multicylinder Aircraft Engine as Affected by Compression Ratio and Engine Operating Conditions

NASA Technical Reports Server (NTRS)

Brun, Rinaldo J.; Feder, Melvin S.; Harries, Myron L.

1947-01-01

An investigation was conducted on a 12-cylinder V-type liquid-cooled aircraft engine of 1710-cubic-inch displacement to determine the minimum specific fuel consumption at constant cruising engine speed and compression ratios of 6.65, 7.93, and 9.68. At each compression ratio, the effect.of the following variables was investigated at manifold pressures of 28, 34, 40, and 50 inches of mercury absolute: temperature of the inlet-air to the auxiliary-stage supercharger, fuel-air ratio, and spark advance. Standard sea-level atmospheric pressure was maintained at the auxiliary-stage supercharger inlet and the exhaust pressure was atmospheric. Advancing the spark timing from 34 deg and 28 deg B.T.C. (exhaust and intake, respectively) to 42 deg and 36 deg B.T.C. at a compression ratio of 6.65 resulted in a decrease of approximately 3 percent in brake specific fuel consumption. Further decreases in brake specific fuel consumption of 10.5 to 14.1 percent (depending on power level) were observed as the compression ratio was increased from 6.65 to 9.68, maintaining at each compression ratio the spark advance required for maximum torque at a fuel-air ratio of 0.06. This increase in compression ratio with a power output of 0.585 horsepower per cubic inch required a change from . a fuel- lend of 6-percent triptane with 94-percent 68--R fuel at a compression ratio of 6.65 to a fuel blend of 58-percent, triptane with 42-percent 28-R fuel at a compression ratio of 9.68 to provide for knock-free engine operation. As an aid in the evaluation of engine mechanical endurance, peak cylinder pressures were measured on a single-cylinder engine at several operating conditions. Peak cylinder pressures of 1900 pounds per square inch can be expected at a compression ratio of 9.68 and an indicated mean effective pressure of 320 pounds per square inch. The engine durability was considerably reduced at these conditions.

Electrical and mechanical stimulation of cardiac cells and tissue constructs.

PubMed

Stoppel, Whitney L; Kaplan, David L; Black, Lauren D

2016-01-15

The field of cardiac tissue engineering has made significant strides over the last few decades, highlighted by the development of human cell derived constructs that have shown increasing functional maturity over time, particularly using bioreactor systems to stimulate the constructs. However, the functionality of these tissues is still unable to match that of native cardiac tissue and many of the stem-cell derived cardiomyocytes display an immature, fetal like phenotype. In this review, we seek to elucidate the biological underpinnings of both mechanical and electrical signaling, as identified via studies related to cardiac development and those related to an evaluation of cardiac disease progression. Next, we review the different types of bioreactors developed to individually deliver electrical and mechanical stimulation to cardiomyocytes in vitro in both two and three-dimensional tissue platforms. Reactors and culture conditions that promote functional cardiomyogenesis in vitro are also highlighted. We then cover the more recent work in the development of bioreactors that combine electrical and mechanical stimulation in order to mimic the complex signaling environment present in vivo. We conclude by offering our impressions on the important next steps for physiologically relevant mechanical and electrical stimulation of cardiac cells and engineered tissue in vitro. Copyright © 2015 Elsevier B.V. All rights reserved.

Jet engine noise and infrared plume correlation field campaign

NASA Astrophysics Data System (ADS)

Cunio, Phillip M.; Weber, Reed A.; Knobel, Kimberly R.; Smith, Christine; Draudt, Andy

2015-09-01

Jet engine noise can be a health hazard and environmental pollutant, particularly affecting personnel working in close proximity to jet engines, such as airline mechanics. Mitigating noise could reduce the potential for hearing loss in runway workers; however, there exists a very complex relationship between jet engine design parameters, operating conditions, and resultant noise power levels, and understanding and characterizing this relationship is a key step in mitigating jet engine noise effects. We demonstrate initial results highlighting the utility of high-speed imaging (hypertemporal imaging) in correlating the infrared signatures of jet engines with acoustic noise. This paper builds on prior theoretical analysis of jet engine infrared signatures and their potential relationships to jet engine acoustic emissions. This previous work identified the region of the jet plume most likely to emit both in infrared and in acoustic domains, and it prompted the investigation of wave packets as a physical construct tying together acoustic and infrared energy emissions. As a means of verifying these assertions, a field campaign to collect relevant data was proposed, and data collection was carried out with a bank of infrared instruments imaging a T700 turboshaft engine undergoing routine operational testing. The detection of hypertemporal signatures in association with acoustic signatures of jet engines enables the use of a new domain in characterizing jet engine noise. This may in turn enable new methods of predicting or mitigating jet engine noise, which could lead to socioeconomic benefits for airlines and other operators of large numbers of jet engines.

AUTOMOTIVE DIESEL MAINTENANCE 1. UNIT VI, MAINTAINING MECHANICAL GOVERNORS--DETROIT DIESEL ENGINES.

ERIC Educational Resources Information Center

Human Engineering Inst., Cleveland, OH.

THIS MODULE OF A 30-MODULE COURSE IS DESIGNED TO DEVELOP AN UNDERSTANDING OF THE OPERATION AND MAINTENANCE OF MECHANICAL GOVERNORS USED ON DIESEL ENGINES. TOPICS ARE (1) TYPES OF GOVERNORS AND ENGINE LOCATION, (2) GOVERNOR APPLICATIONS, (3) LIMITING SPEED MECHANICAL GOVERNOR, (4) VARIABLE SPEED MECHANICAL GOVERNOR, AND (5) CONSTANT SPEED…

Engineering 3D Cellularized Collagen Gels for Vascular Tissue Regeneration.

PubMed

Meghezi, Sébastien; Seifu, Dawit G; Bono, Nina; Unsworth, Larry; Mequanint, Kibret; Mantovani, Diego

2015-06-16

Synthetic materials are known to initiate clinical complications such as inflammation, stenosis, and infections when implanted as vascular substitutes. Collagen has been extensively used for a wide range of biomedical applications and is considered a valid alternative to synthetic materials due to its inherent biocompatibility (i.e., low antigenicity, inflammation, and cytotoxic responses). However, the limited mechanical properties and the related low hand-ability of collagen gels have hampered their use as scaffold materials for vascular tissue engineering. Therefore, the rationale behind this work was first to engineer cellularized collagen gels into a tubular-shaped geometry and second to enhance smooth muscle cells driven reorganization of collagen matrix to obtain tissues stiff enough to be handled. The strategy described here is based on the direct assembling of collagen and smooth muscle cells (construct) in a 3D cylindrical geometry with the use of a molding technique. This process requires a maturation period, during which the constructs are cultured in a bioreactor under static conditions (without applied external dynamic mechanical constraints) for 1 or 2 weeks. The "static bioreactor" provides a monitored and controlled sterile environment (pH, temperature, gas exchange, nutrient supply and waste removal) to the constructs. During culture period, thickness measurements were performed to evaluate the cells-driven remodeling of the collagen matrix, and glucose consumption and lactate production rates were measured to monitor the cells metabolic activity. Finally, mechanical and viscoelastic properties were assessed for the resulting tubular constructs. To this end, specific protocols and a focused know-how (manipulation, gripping, working in hydrated environment, and so on) were developed to characterize the engineered tissues.

Molecular communication and networking: opportunities and challenges.

PubMed

Nakano, Tadashi; Moore, Michael J; Wei, Fang; Vasilakos, Athanasios V; Shuai, Jianwei

2012-06-01

The ability of engineered biological nanomachines to communicate with biological systems at the molecular level is anticipated to enable future applications such as monitoring the condition of a human body, regenerating biological tissues and organs, and interfacing artificial devices with neural systems. From the viewpoint of communication theory and engineering, molecular communication is proposed as a new paradigm for engineered biological nanomachines to communicate with the natural biological nanomachines which form a biological system. Distinct from the current telecommunication paradigm, molecular communication uses molecules as the carriers of information; sender biological nanomachines encode information on molecules and release the molecules in the environment, the molecules then propagate in the environment to receiver biological nanomachines, and the receiver biological nanomachines biochemically react with the molecules to decode information. Current molecular communication research is limited to small-scale networks of several biological nanomachines. Key challenges to bridge the gap between current research and practical applications include developing robust and scalable techniques to create a functional network from a large number of biological nanomachines. Developing networking mechanisms and communication protocols is anticipated to introduce new avenues into integrating engineered and natural biological nanomachines into a single networked system. In this paper, we present the state-of-the-art in the area of molecular communication by discussing its architecture, features, applications, design, engineering, and physical modeling. We then discuss challenges and opportunities in developing networking mechanisms and communication protocols to create a network from a large number of bio-nanomachines for future applications.

A probabilistic approach to randomness in geometric configuration of scalable origami structures

NASA Astrophysics Data System (ADS)

Liu, Ke; Paulino, Glaucio; Gardoni, Paolo

2015-03-01

Origami, an ancient paper folding art, has inspired many solutions to modern engineering challenges. The demand for actual engineering applications motivates further investigation in this field. Although rooted from the historic art form, many applications of origami are based on newly designed origami patterns to match the specific requirenments of an engineering problem. The application of origami to structural design problems ranges from micro-structure of materials to large scale deployable shells. For instance, some origami-inspired designs have unique properties such as negative Poisson ratio and flat foldability. However, origami structures are typically constrained by strict mathematical geometric relationships, which in reality, can be easily violated, due to, for example, random imperfections introduced during manufacturing, or non-uniform deformations under working conditions (e.g. due to non-uniform thermal effects). Therefore, the effects of uncertainties in origami-like structures need to be studied in further detail in order to provide a practical guide for scalable origami-inspired engineering designs. Through reliability and probabilistic analysis, we investigate the effect of randomness in origami structures on their mechanical properties. Dislocations of vertices of an origami structure have different impacts on different mechanical properties, and different origami designs could have different sensitivities to imperfections. Thus we aim to provide a preliminary understanding of the structural behavior of some common scalable origami structures subject to randomness in their geometric configurations in order to help transition the technology toward practical applications of origami engineering.

Insights to regenerate materials: learning from nature

NASA Astrophysics Data System (ADS)

García-Aznar, J. M.; Valero, C.; Gómez-Benito, M. J.; Javierre, E.

2016-08-01

Self-healing materials, both biological and engineered, integrate the ability to repair themselves and recover their functionality using the resources inherently available to them. Although significant advances have been made, in recent years, for the design of different concepts of self-healing materials, this work aims to provide some insights into how living materials are able to regenerate or heal when a fracture or injury occurs. The main sensors that regulate this adaptive and regenerative behavior are the cells. These are able to sense the mechanical alterations in their surroundings and regulate their activity in order to remove dead tissue and/or create new tissue. Therefore, understanding how cells are able to regenerate tissues under complex and multiphysics conditions can define the biomimetics guidelines to heal through inert or traditional engineering materials. In this work, we present a combination of experiments and different kinds of multiscale and multiphysics models in order to understand how mechanics regulate some mechanisms at cell and tissue level. This combination of results aims to gain insight into the development of novel strategies for self-healing materials, mimicking the behavior induced by cells and biological tissues.

Resident research associateships. Postdoctoral and senior research awards: Opportunities for research at the Jet Propulsion Laboratory

NASA Technical Reports Server (NTRS)

1984-01-01

Opportunities for research as part of NASA-sponsored programs at the JPL cover: Earth and space sciences; systems; telecommunications science and engineering; control and energy conversion; applied mechanics; information systems; and observational systems. General information on applying for an award for tenure as a guest investigator, conditions, of the award, and details of the application procedure are provided.

Preparing Technical Requirements for Third Party Contracting of Army Facilities

DTIC Science & Technology

1993-06-01

Boiler and Pressure Vessel Code Sec 9 Welding and Brazing Qualifications B 16.1 Cast Iron Pipe Flanges and Flanged...Control Terminology for Heating, Ventilating, Air Conditioning American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code B40.1...American National Standards Institute (ANSI) Boiler and Pressure Vessel Code (ASME) 125 Boilers and Pressure Vessels Code (ASTM) B31 Power

Targeting Biological Sensing with Commercial SERS Substrates

DTIC Science & Technology

2012-09-01

ORGANIZATION NAME(S) AND ADDRESS(ES) U.S. Army Research Laboratory ATTN: RDRL-SEE-E 2800 Powder Mill Road Adelphi, MD 20783-1197 8. PERFORMING...Pellegrino* *U.S. Army Research Laboratories, RDRL-SEE-E, 2800 Powder Mill Road, Adelphi, Maryland 20783 Department of Mechanical Engineering and...demonstrated typical RSDs ranging from 10-15% under drop and dry conditions. While these standard Klarite substrates do demonstrate a high

Mechanical Stimulation of Adipose-Derived Stem Cells for Functional Tissue Engineering of the Musculoskeletal System via Cyclic Hydrostatic Pressure, Simulated Microgravity, and Cyclic Tensile Strain.

PubMed

Nordberg, Rachel C; Bodle, Josie C; Loboa, Elizabeth G

2018-01-01

It is critical that human adipose stem cell (hASC) tissue-engineering therapies possess appropriate mechanical properties in order to restore function of the load bearing tissues of the musculoskeletal system. In an effort to elucidate the hASC response to mechanical stimulation and develop mechanically robust tissue engineered constructs, recent research has utilized a variety of mechanical loading paradigms including cyclic tensile strain, cyclic hydrostatic pressure, and mechanical unloading in simulated microgravity. This chapter describes methods for applying these mechanical stimuli to hASC to direct differentiation for functional tissue engineering of the musculoskeletal system.

NASA's Advanced Environmental Barrier Coatings Development for SiC/SiC Ceramic Matrix Composites: Understanding Calcium Magnesium Alumino-Silicate (CMAS) Degradations and Resistance

NASA Technical Reports Server (NTRS)

Zhu, Dongming

2014-01-01

Environmental barrier coatings (EBCs) and SiCSiC ceramic matrix composites (CMCs) systems will play a crucial role in next generation turbine engines for hot-section component applications because of their ability to significantly increase engine operating temperatures with improved efficiency, reduce engine weight and cooling requirements. The development of prime-reliant environmental barrier coatings is essential to the viability and reliability of the envisioned CMC engine component applications, ensuring integrated EBC-CMC system durability and designs are achievable for successful applications of the game-changing component technologies and lifing methodologies.This paper will emphasize recent NASA environmental barrier coating developments for SiCSiC turbine airfoil components, utilizing advanced coating compositions, state-of-the-art processing methods, and combined mechanical and environment testing and durability evaluations. The coating-CMC degradations in the engine fatigue-creep and operating environments are particularly complex; one of the important coating development aspects is to better understand engine environmental interactions and coating life debits, and we have particularly addressed the effect of Calcium-Magnesium-Alumino-Silicate (CMAS) from road sand or volcano-ash deposits on the durability of the environmental barrier coating systems, and how the temperature capability, stability and cyclic life of the candidate rare earth oxide and silicate coating systems will be impacted in the presence of the CMAS at high temperatures and under simulated heat flux conditions. Advanced environmental barrier coating systems, including HfO2-Si with rare earth dopant based bond coat systems, will be discussed for the performance improvements to achieve better temperature capability and CMAS resistance for future engine operating conditions.

Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies.

PubMed

Tzatzalos, Evangeline; Abilez, Oscar J; Shukla, Praveen; Wu, Joseph C

2016-01-15

Engineered heart tissue has emerged as a personalized platform for drug screening. With the advent of induced pluripotent stem cell (iPSC) technology, patient-specific stem cells can be developed and expanded into an indefinite source of cells. Subsequent developments in cardiovascular biology have led to efficient differentiation of cardiomyocytes, the force-producing cells of the heart. iPSC-derived cardiomyocytes (iPSC-CMs) have provided potentially limitless quantities of well-characterized, healthy, and disease-specific CMs, which in turn has enabled and driven the generation and scale-up of human physiological and disease-relevant engineered heart tissues. The combined technologies of engineered heart tissue and iPSC-CMs are being used to study diseases and to test drugs, and in the process, have advanced the field of cardiovascular tissue engineering into the field of precision medicine. In this review, we will discuss current developments in engineered heart tissue, including iPSC-CMs as a novel cell source. We examine new research directions that have improved the function of engineered heart tissue by using mechanical or electrical conditioning or the incorporation of non-cardiomyocyte stromal cells. Finally, we discuss how engineered heart tissue can evolve into a powerful tool for therapeutic drug testing. Copyright © 2015 Elsevier B.V. All rights reserved.

[Steady car engine noise does not affect the cognitive abilities of sleep apnea syndrome patients].

PubMed

Mayoralas, L R; Barbé, F; Muñoz, A; Agustí, A G N

2003-09-01

Traffic accidents are more frequent for sleep apnea syndrome (SAS) patients than in the population at large. The mechanisms that underlie this observation are poorly defined. Our working hypothesis was that in SAS patients the steady noise of a car engine might alter cognitive capacities that may be involved in driving, thus increasing the risk of traffic accidents. To test this hypothesis we designed a prospective randomized controlled trial. Eighteen SAS patients (apnea-hypopnea index [SEM] 62 [6] h1) and 18 healthy controls were studied. All the participants were evaluated in random order both in basal conditions and after exposure to the steady noise of a car engine recorded on a compact disc. Their level of vigilance was evaluated (Steer-Clear) as well as their reaction time (PVT 192). Attention, coordination, and memory were measured using the following tests: Wechsler Memory Scale (digit span), the Wechsler Intelligence Scale (digit symbol), and Lezack's Trail Making tests A and B. The SAS patients were slightly younger than the control group (mean 50 [7] vs 57 [11] years, respectively; P=.05). The patients showed a lower level of vigilance than the controls both in basal and engine noise conditions (P<.05). No differences between groups were found for the other variables studied. Exposure to steady car engine noise had no effect on the tests of either group. In conclusion, the results of our study do not support the hypothesis that steady car engine noise significantly alters the cognitive ability of SAS patients.

A Bioreactor to Identify the Driving Mechanical Stimuli of Tissue Growth and Remodeling.

PubMed

van Kelle, Mathieu A J; Oomen, Pim J A; Bulsink, Jurgen A; Janssen-van den Broek, Marloes W J T; Lopata, Richard G P; Rutten, Marcel C M; Loerakker, Sandra; Bouten, Carlijn V C

2017-06-01

Tissue growth and remodeling are essential processes that should ensure long-term functionality of tissue-engineered (TE) constructs. Even though it is widely recognized that these processes strongly depend on mechanical stimuli, the underlying mechanisms of mechanically induced growth and remodeling are only partially understood. It is generally accepted that cells sense mechanical changes and respond by altering their surroundings, by means of extracellular matrix growth and remodeling, in an attempt to return to a certain preferred mechanical homeostatic state. However, the exact mechanical cues that trigger cells to synthesize and remodel their environment remain unclear. To identify the driving mechanical stimuli of these processes, it is critical to be able to temporarily follow the mechanical state of developing tissues under physiological loading conditions. Therefore, a novel "versatile tissue growth and remodeling" (Vertigro) bioreactor was developed that is capable of tissue culture and mechanical stimulation for a prolonged time period, while simultaneously performing mechanical testing. The Vertigro's unique two-chamber design allows easy, sterile handling of circular 3D TE constructs in a dedicated culture chamber, while a separate pressure chamber facilitates a pressure-driven dynamic loading regime during culture. As a proof-of-concept, temporal changes in the mechanical state of cultured tissues were quantified using nondestructive mechanical testing by means of a classical bulge test, in which the tissue displacement was tracked using ultrasound imaging. To demonstrate the successful development of the bioreactor system, compositional, structural, and geometrical changes were qualitatively and quantitatively assessed using a series of standard analysis techniques. With this bioreactor and associated mechanical analysis technique, a powerful toolbox has been developed to quantitatively study and identify the driving mechanical stimuli of engineered tissue growth and remodeling.

Optimized suspension culture: the rotating-wall vessel

NASA Technical Reports Server (NTRS)

Hammond, T. G.; Hammond, J. M.

2001-01-01

Suspension culture remains a popular modality, which manipulates mechanical culture conditions to maintain the specialized features of cultured cells. The rotating-wall vessel is a suspension culture vessel optimized to produce laminar flow and minimize the mechanical stresses on cell aggregates in culture. This review summarizes the engineering principles, which allow optimal suspension culture conditions to be established, and the boundary conditions, which limit this process. We suggest that to minimize mechanical damage and optimize differentiation of cultured cells, suspension culture should be performed in a solid-body rotation Couette-flow, zero-headspace culture vessel such as the rotating-wall vessel. This provides fluid dynamic operating principles characterized by 1) solid body rotation about a horizontal axis, characterized by colocalization of cells and aggregates of different sedimentation rates, optimally reduced fluid shear and turbulence, and three-dimensional spatial freedom; and 2) oxygenation by diffusion. Optimization of suspension culture is achieved by applying three tradeoffs. First, terminal velocity should be minimized by choosing microcarrier beads and culture media as close in density as possible. Next, rotation in the rotating-wall vessel induces both Coriolis and centrifugal forces, directly dependent on terminal velocity and minimized as terminal velocity is minimized. Last, mass transport of nutrients to a cell in suspension culture depends on both terminal velocity and diffusion of nutrients. In the transduction of mechanical culture conditions into cellular effects, several lines of evidence support a role for multiple molecular mechanisms. These include effects of shear stress, changes in cell cycle and cell death pathways, and upstream regulation of secondary messengers such as protein kinase C. The discipline of suspension culture needs a systematic analysis of the relationship between mechanical culture conditions and biological effects, emphasizing cellular processes important for the industrial production of biological pharmaceuticals and devices.

A factorial design to identify process parameters affecting whole mechanically disrupted rat pancreata in a perfusion bioreactor.

PubMed

Sharp, Jamie; Spitters, Tim Wgm; Vermette, Patrick

2018-03-01

Few studies report whole pancreatic tissue culture, as it is a difficult task using traditional culture methods. Here, a factorial design was used to investigate the singular and combinational effects of flow, dissolved oxygen concentration (D.O.) and pulsation on whole mechanically disrupted rat pancreata in a perfusion bioreactor. Whole rat pancreata were cultured for 72 h under defined bioreactor process conditions. Secreted insulin was measured and histological (haematoxylin and eosin (H&E)) as well as immunofluorescent insulin staining were performed and quantified. The combination of flow and D.O. had the most significant effect on secreted insulin at 5 h and 24 h. The D.O. had the biggest effect on tissue histological quality, and pulsation had the biggest effect on the number of insulin-positive structures. Based on the factorial design analysis, bioreactor conditions using high flow, low D.O., and pulsation were selected to further study glucose-stimulated insulin secretion. Here, mechanically disrupted rat pancreata were cultured for 24 h under these bioreactor conditions and were then challenged with high glucose concentration for 6 h and high glucose + IBMX (an insulin secretagogue) for a further 6 h. These cultures secreted insulin in response to high glucose concentration in the first 6 h, however stimulated-insulin secretion was markedly weaker in response to high glucose concentration + IBMX thereafter. After this bioreactor culture period, higher tissue metabolic activity was found compared to that of non-bioreacted static controls. More insulin- and glucagon-positive structures, and extensive intact endothelial structures were observed compared to non-bioreacted static cultures. H&E staining revealed more intact tissue compared to static cultures. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 34:432-444, 2018. © 2017 American Institute of Chemical Engineers.

Growth factor delivery for oral and periodontal tissue engineering

PubMed Central

Kaigler, Darnell; Cirelli, Joni A; Giannobile, William V

2008-01-01

The treatment of oral and periodontal diseases and associated anomalies accounts for a significant proportion of the healthcare burden, with the manifestations of these conditions being functionally and psychologically debilitating. Growth factors are critical to the development, maturation, maintenance and repair of craniofacial tissues, as they establish an extracellular environment that is conducive to cell and tissue growth. Tissue-engineering principles aim to exploit these properties in the development of biomimetic materials that can provide an appropriate microenvironment for tissue development. These materials have been constructed into devices that can be used as vehicles for delivery of cells, growth factors and DNA. In this review, different mechanisms of drug delivery are addressed in the context of novel approaches to reconstruct and engineer oral- and tooth-supporting structures, namely the periodontium and alveolar bone. PMID:16948560

Engineering Lipases: walking the fine line between activity and stability

NASA Astrophysics Data System (ADS)

Dasetty, Siva; Blenner, Mark A.; Sarupria, Sapna

2017-11-01

Lipases are enzymes that hydrolyze lipids and have several industrial applications. There is a tremendous effort in engineering the activity, specificity and stability of lipases to render them functional in a variety of environmental conditions. In this review, we discuss the recent experimental and simulation studies focused on engineering lipases. Experimentally, mutagenesis studies have demonstrated that the activity, stability, and specificity of lipases can be modulated by mutations. It has been particularly challenging however, to elucidate the underlying mechanisms through which these mutations affect the lipase properties. We summarize results from experiments and molecular simulations highlighting the emerging picture to this end. We end the review with suggestions for future research which underscores the delicate balance of various facets in the lipase that affect their activity and stability necessitating the consideration of the enzyme as a network of interactions.

Cell encapsulation in biodegradable hydrogels for tissue engineering applications.

PubMed

Nicodemus, Garret D; Bryant, Stephanie J

2008-06-01

Encapsulating cells in biodegradable hydrogels offers numerous attractive features for tissue engineering, including ease of handling, a highly hydrated tissue-like environment for cell and tissue growth, and the ability to form in vivo. Many properties important to the design of a hydrogel scaffold, such as swelling, mechanical properties, degradation, and diffusion, are closely linked to the crosslinked structure of the hydrogel, which is controlled through a variety of different processing conditions. Degradation may be tuned by incorporating hydrolytically or enzymatically labile segments into the hydrogel or by using natural biopolymers that are susceptible to enzymatic degradation. Because cells are present during the gelation process, the number of suitable chemistries and formulations are limited. In this review, we describe important considerations for designing biodegradable hydrogels for cell encapsulation and highlight recent advances in material design and their applications in tissue engineering.

Reuse of Aluminum Dross as an Engineered Product

NASA Astrophysics Data System (ADS)

Dai, Chen; Apelian, Diran

To prevent the leaching of landfilled aluminum dross waste and save the energy consumed by recovering metallic aluminum from dross, aluminum dross is reused as an engineering product directly rather than "refurbished" ineffectively. The concept is to reduce waste and to reuse. Two kinds of aluminum dross from industrial streams were selected and characterized. We have shown that dross can be applied directly, or accompanied with a simple conditioning process, to manufacture refractory components. Dross particles below 50 mesh are most effective. Mechanical property evaluations revealed the possibility for dross waste to be utilized as filler in concrete, resulting in up to 40% higher flexural strength and 10% higher compressive strength compared to pure cement, as well as cement with sand additions. The potential usage of aluminum dross as a raw material for such engineering applications is presented and discussed.

Strengthening Precipitate Morphologies Fully Quantified in Advanced Disk Superalloys

NASA Technical Reports Server (NTRS)

Gabb, Timothy P.

1998-01-01

Advanced aviation gas turbine engines will require disk superalloys that can operate at higher temperatures and stresses than current conditions. Such applications will be limited by the tensile, creep, and fatigue mechanical properties of these alloys. These mechanical properties vary with the size, shape, and quantity of the gamma precipitates that strengthen disk superalloys. It is therefore important to quantify these precipitate parameters and relate them to mechanical properties to improve disk superalloys. Favorable precipitate morphologies and practical processing approaches to achieve them can then be determined. A methodology has been developed at the NASA Lewis Research Center to allow the comprehensive quantification of the size, shape, and quantity of all types of gamma precipitates.

Investigation of Thermal High Cycle and Low Cycle Fatigue Mechanisms of Thick Thermal Barrier Coatings

NASA Technical Reports Server (NTRS)

Zhu, Dongming; Miller, Robert A.

1998-01-01

Thick thermal barrier coating systems in a diesel engine experience severe thermal low cycle fatigue (LCF) and high cycle fatigue (HCF) during engine operation. In this paper, the mechanisms of fatigue crack initiation and propagation in a ZrO2-8wt.% Y2O3 thermal barrier coating, under simulated engine thermal LCF and HCF conditions, are investigated using a high power CO2 laser. Experiments showed that the combined LCF/HCF tests induced more severe coating surface cracking, microspallation and accelerated crack growth, as compared to the pure LCF test. Lateral crack branching and the ceramic/bond coat interface delaminations were also facilitated by HCF thermal loads, even in the absence of severe interfacial oxidation. Fatigue damages at crack wake surfaces, due to such phenomena as asperity/debris contact induced cracking and splat pull-out bending during cycling, were observed especially for the combined LCF/HCF tests. It is found that the failure associated with LCF is closely related to coating sintering and creep at high temperatures, which induce tensile stresses in the coating after cooling. The failure associated with HCF process, however, is mainly associated with a surface wedging mechanism. The interaction between the LCF, HCF and ceramic coating creep, and the relative importance of LCF and HCF in crack propagation are also discussed based on the experimental evidence.

Indirect three-dimensional printing: A method for fabricating polyurethane-urea based cardiac scaffolds.

PubMed

Hernández-Córdova, R; Mathew, D A; Balint, R; Carrillo-Escalante, H J; Cervantes-Uc, J M; Hidalgo-Bastida, L A; Hernández-Sánchez, F

2016-08-01

Biomaterial scaffolds are a key part of cardiac tissue engineering therapies. The group has recently synthesized a novel polycaprolactone based polyurethane-urea copolymer that showed improved mechanical properties compared with its previously published counterparts. The aim of this study was to explore whether indirect three-dimensional (3D) printing could provide a means to fabricate this novel, biodegradable polymer into a scaffold suitable for cardiac tissue engineering. Indirect 3D printing was carried out through printing water dissolvable poly(vinyl alcohol) porogens in three different sizes based on a wood-stack model, into which a polyurethane-urea solution was pressure injected. The porogens were removed, leading to soft polyurethane-urea scaffolds with regular tubular pores. The scaffolds were characterized for their compressive and tensile mechanical behavior; and their degradation was monitored for 12 months under simulated physiological conditions. Their compatibility with cardiac myocytes and performance in novel cardiac engineering-related techniques, such as aggregate seeding and bi-directional perfusion, was also assessed. The scaffolds were found to have mechanical properties similar to cardiac tissue, and good biocompatibility with cardiac myocytes. Furthermore, the incorporated cells preserved their phenotype with no signs of de-differentiation. The constructs worked well in perfusion experiments, showing enhanced seeding efficiency. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 104A: 1912-1921, 2016. © 2016 Wiley Periodicals, Inc.

Multiscale Thermo-Mechanical Design and Analysis of High Frequency and High Power Vacuum Electron Devices

NASA Astrophysics Data System (ADS)

Gamzina, Diana

Diana Gamzina March 2016 Mechanical and Aerospace Engineering Multiscale Thermo-Mechanical Design and Analysis of High Frequency and High Power Vacuum Electron Devices Abstract A methodology for performing thermo-mechanical design and analysis of high frequency and high average power vacuum electron devices is presented. This methodology results in a "first-pass" engineering design directly ready for manufacturing. The methodology includes establishment of thermal and mechanical boundary conditions, evaluation of convective film heat transfer coefficients, identification of material options, evaluation of temperature and stress field distributions, assessment of microscale effects on the stress state of the material, and fatigue analysis. The feature size of vacuum electron devices operating in the high frequency regime of 100 GHz to 1 THz is comparable to the microstructure of the materials employed for their fabrication. As a result, the thermo-mechanical performance of a device is affected by the local material microstructure. Such multiscale effects on the stress state are considered in the range of scales from about 10 microns up to a few millimeters. The design and analysis methodology is demonstrated on three separate microwave devices: a 95 GHz 10 kW cw sheet beam klystron, a 263 GHz 50 W long pulse wide-bandwidth sheet beam travelling wave tube, and a 346 GHz 1 W cw backward wave oscillator.

Welcoming speech from Dean Faculty of Mechanical Engineering, UMP

NASA Astrophysics Data System (ADS)

Taha, Zahari

2012-09-01

In the Name of Allah, the Most Beneficent, the Most Merciful. It is with great pleasure that I welcome the participants of the International Conference of Mechanical Engineering Research 2011. The Prophet Muhammad (peace be upon him) said 'Acquire knowledge and impart it to the people.' (Al Tirmidhi). The quest for knowledge has been from the beginning of time but knowledge only becomes valuable when it is disseminated and applied to benefit humankind. It is hoped that ICMER 2011 will be a platform to gather and disseminate the latest knowledge in mechanical engineering. Academicians, Scientist, Researchers and practitioners of mechanical engineering will be able to share and discuss new findings and applications of mechanical engineering. It is envisaged that the intellectual discourse will result in future collaborations between universities, research institutions and industry both locally and internationally. In particular it is expected that focus will be given to issues on environmental and energy sustainability. Researchers in the mechanical engineering faculty at UMP have a keen interest in technology to harness energy from the ocean. Lowering vehicle emissions has been a primary goal of researchers in the mechanical engineering faculty and the automotive engineering centre as well including developing vehicles using alternative fuels such as biodiesel and renewable sources such as solar driven electric vehicles. Finally I would like to congratulate the organizing committee for their tremendous efforts in organizing the conference. As I wrote this in the Holy Land of Makkah, I pray to Allah swt that the conference will be a success. Prof. Dr. Zahari Taha CEng, MIED, FASc Dean, Faculty of Mechanical Engineering Universiti Malaysia Pahang

Mechanical Objects and the Engineering Learner: An Experimental Study of How the Presence of Objects Affects Students' Performance on Engineering Related Tasks

ERIC Educational Resources Information Center

Bairaktarova, Diana N.

2013-01-01

People display varying levels of interaction with the mechanical objects in their environment; engineers in particular as makers and users of these objects display a higher level of interaction with them. Investigating the educational potential of mechanical objects in stimulating and supporting learning in engineering is warranted by the fact…

Microstructural and superficial modification in a Cu-Al-Be shape memory alloy due to superficial severe plastic deformation under sliding wear conditions

NASA Astrophysics Data System (ADS)

Figueroa, C. G.; Garcia-Castillo, F. N.; Jacobo, V. H.; Cortés-Pérez, J.; Schouwenaars, R.

2017-05-01

Stress induced martensitic transformation in copper-based shape memory alloys has been studied mainly in monocrystals. This limits the use of such results for practical applications as most engineering applications use polycristals. In the present work, a coaxial tribometer developed by the authors was used to characterise the tribological behaviour of polycrystalline Cu-11.5%Al-0.5%Be shape memory alloy in contact with AISI 9840 steel under sliding wear conditions. The surface and microstructure characterization of the worn material was conducted by conventional scanning electron microscopy and atomic force microscopy, while the mechanical properties along the transversal section were measured by means of micro-hardness testing. The tribological behaviour of Cu-Al-Be showed to be optimal under sliding wear conditions since the surface only presented a slight damage consisting in some elongated flakes produced by strong plastic deformation. The combination of the plastically modified surface and the effects of mechanically induced martensitic transformation is well-suited for sliding wear conditions since the modified surface provides the necessary strength to avoid superficial damage while superelasticity associated to martensitic transformation is an additional mechanism which allows absorbing mechanical energy associated to wear phenomena as opposed to conventional ductile alloys where severe plastic deformation affects several tens of micrometres below the surface.

Job Prospects for Mechanical Engineers.

ERIC Educational Resources Information Center

Basta, Nicholas

1986-01-01

Discusses the career outlook for mechanical engineers. Explains that the number of bachelor degrees awarded yearly has reached a plateau, but salaries continue to rise. Suggests that the largest increase in demand for mechanical engineers will come from industries involved in automation, particularly those developing robotics. (TW)

Intermetallic and ceramic matrix composites for 815 to 1370 C (1500 to 2500 F) gas turbine engine applications

NASA Technical Reports Server (NTRS)

Stephens, Joseph R.

1989-01-01

Light weight and potential high temperature capability of intermetallic compounds, such as the aluminides, and structural ceramics, such as the carbides and nitrides, make these materials attractive for gas turbine engine applications. In terms of specific fuel consumption and specific thrust, revolutionary improvements over current technology are being sought by realizing the potential of these materials through their use as matrices combined with high strength, high temperature fibers. The U.S. along with other countries throughout the world have major research and development programs underway to characterize these composites materials; improve their reliability; identify and develop new processing techniques, new matrix compositions, and new fiber compositions; and to predict their life and failure mechanisms under engine operating conditions. The status is summarized of NASA's Advanced High Temperature Engine Materials Technology Program (HITEMP) and the potential benefits are described to be gained in 21st century transport aircraft by utilizing intermetallic and ceramic matrix composite materials.

The 10 MWe Solar Thermal Central Receiver Pilot Plant: Solar facilities design integration. Pilot-plant station manual (RADL Item 2-1). Volume 1: System description

NASA Astrophysics Data System (ADS)

1982-09-01

The complete Barstow Solar Pilot Plant is described. The plant requirements and general description are presented, the mechanical, electric power, and control and instrumentation systems as well as civil engineering and structural aspects and the station buildings are described. Included in the mechanical systems are the heliostats, receiver, thermal storage system, beam characterization system, steam, water, nitrogen, and compressed air systems, chemical feed system, fire protection system, drains, sumps and the waste disposal systems, and heating, ventilating, and air conditioning systems.

Weighted reciprocal of temperature, weighted thermal flux, and their applications in finite-time thermodynamics.

PubMed

Sheng, Shiqi; Tu, Z C

2014-01-01

The concepts of weighted reciprocal of temperature and weighted thermal flux are proposed for a heat engine operating between two heat baths and outputting mechanical work. With the aid of these two concepts, the generalized thermodynamic fluxes and forces can be expressed in a consistent way within the framework of irreversible thermodynamics. Then the efficiency at maximum power output for a heat engine, one of key topics in finite-time thermodynamics, is investigated on the basis of a generic model under the tight-coupling condition. The corresponding results have the same forms as those of low-dissipation heat engines [ M. Esposito, R. Kawai, K. Lindenberg and C. Van den Broeck Phys. Rev. Lett. 105 150603 (2010)]. The mappings from two kinds of typical heat engines, such as the low-dissipation heat engine and the Feynman ratchet, into the present generic model are constructed. The universal efficiency at maximum power output up to the quadratic order is found to be valid for a heat engine coupled symmetrically and tightly with two baths. The concepts of weighted reciprocal of temperature and weighted thermal flux are also transplanted to the optimization of refrigerators.

An engineering approach to controlling indoor air quality.

PubMed

Woods, J E

1991-11-01

Evidence is accumulating that indicates air quality problems in residential and commercial buildings are nearly always associated with inadequacies in building design and methods of operation. Thus, the very systems depended on to control the indoor environment can become indirect sources of contamination if diligence is not exercised at each stage of a building's life: a) planning and design, b) construction and commissioning, c) operation, and d) demolition or renovation. In this paper, an engineering perspective is presented in which the existing building stock is characterized in terms of its environmental performance. Preliminary data indicate that 20 to 30% of the existing buildings have sufficient problems to manifest as sick-building syndrome or building-related illness, while another 10 to 20% may have undetected problems. Thus, only about 50 to 70% of the existing buildings qualify as healthy buildings. Two methods and three mechanisms of control are described to achieve "acceptable" indoor air quality: source control and exposure control. If sources cannot be removed, some level of occupant exposure will result. To control exposures with acceptable values, the primary sensory receptors of the occupants (i.e., thermal, ocular, auditory, and olfactory) cannot be excessively stimulated. The three exposure control mechanisms are conduction, radiation, and convection. To achieve acceptable occupant responses, it is often practical to integrate the mechanisms of radiation and convection in heating, ventilating, and air conditioning systems that are designed to provide acceptable thermal, acoustic, and air quality conditions within occupied spaces.(ABSTRACT TRUNCATED AT 250 WORDS)

An engineering approach to controlling indoor air quality.

PubMed Central

Woods, J E

1991-01-01

Evidence is accumulating that indicates air quality problems in residential and commercial buildings are nearly always associated with inadequacies in building design and methods of operation. Thus, the very systems depended on to control the indoor environment can become indirect sources of contamination if diligence is not exercised at each stage of a building's life: a) planning and design, b) construction and commissioning, c) operation, and d) demolition or renovation. In this paper, an engineering perspective is presented in which the existing building stock is characterized in terms of its environmental performance. Preliminary data indicate that 20 to 30% of the existing buildings have sufficient problems to manifest as sick-building syndrome or building-related illness, while another 10 to 20% may have undetected problems. Thus, only about 50 to 70% of the existing buildings qualify as healthy buildings. Two methods and three mechanisms of control are described to achieve "acceptable" indoor air quality: source control and exposure control. If sources cannot be removed, some level of occupant exposure will result. To control exposures with acceptable values, the primary sensory receptors of the occupants (i.e., thermal, ocular, auditory, and olfactory) cannot be excessively stimulated. The three exposure control mechanisms are conduction, radiation, and convection. To achieve acceptable occupant responses, it is often practical to integrate the mechanisms of radiation and convection in heating, ventilating, and air conditioning systems that are designed to provide acceptable thermal, acoustic, and air quality conditions within occupied spaces.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1821369

DI Diesel Performance and Emissions Model

DTIC Science & Technology

1998-03-31

Skeletal mechanism for NOx chemistry in Diesel engines ," SAE Paper 981450. Mori, K. (1997), "Worldwide...Based on the review discussed above, Mellor et al. (1998) postulate a skeletal mechanism for NO chemistry in DI Diesel engines . This mechanism is... mechanism for NOx chemistry in Diesel engines ," SAE Paper 981450. Various Internal Ford Reports, Ford Motor Company, Dearborn, MI. 29

Gasoline Engine Mechanics. Florida Vocational Program Guide.

ERIC Educational Resources Information Center

University of South Florida, Tampa. Dept. of Adult and Vocational Education.

This vocational program guide is intended to assist in the organization, operation, and evaluation of a program in gasoline engine mechanics in school districts, area vocational centers, and community colleges. The following topics are covered: job duties of small-engine mechanics; program content (curriculum framework and student performance…

24 CFR 200.934 - User fee system for the technical suitability of products program.

Code of Federal Regulations, 2012 CFR

2012-04-01

... section establishes fee requirements for the issuance of Structural Engineering Bulletins (SEBs), Mechanical Engineering Bulletins (MEBs), Truss Connector Bulletins (TCBs), Area Letters of Acceptance (ALAs... Department. (i) With respect to Mechanical Engineering Bulletins (MEBs), Structural Engineering Bulletins...

24 CFR 200.934 - User fee system for the technical suitability of products program.

Code of Federal Regulations, 2013 CFR

2013-04-01

... section establishes fee requirements for the issuance of Structural Engineering Bulletins (SEBs), Mechanical Engineering Bulletins (MEBs), Truss Connector Bulletins (TCBs), Area Letters of Acceptance (ALAs... Department. (i) With respect to Mechanical Engineering Bulletins (MEBs), Structural Engineering Bulletins...

24 CFR 200.934 - User fee system for the technical suitability of products program.

Code of Federal Regulations, 2014 CFR

2014-04-01

... section establishes fee requirements for the issuance of Structural Engineering Bulletins (SEBs), Mechanical Engineering Bulletins (MEBs), Truss Connector Bulletins (TCBs), Area Letters of Acceptance (ALAs... Department. (i) With respect to Mechanical Engineering Bulletins (MEBs), Structural Engineering Bulletins...

24 CFR 200.934 - User fee system for the technical suitability of products program.

Code of Federal Regulations, 2011 CFR

2011-04-01

... section establishes fee requirements for the issuance of Structural Engineering Bulletins (SEBs), Mechanical Engineering Bulletins (MEBs), Truss Connector Bulletins (TCBs), Area Letters of Acceptance (ALAs... Department. (i) With respect to Mechanical Engineering Bulletins (MEBs), Structural Engineering Bulletins...

Liquid Behavior at Critical and Supercritical Conditions

NASA Technical Reports Server (NTRS)

Chiu, Huei-Huang; Gross, Klaus W.

1989-01-01

At a JANNAF workshop, the issue of fluids at and above the critical point was discussed to obtain a better understanding of similar conditions in combustion chambers of rocket engines. Invited experts from academic, industrial, and government institutions presented the most recent physical, numerical, and experimental advances. During the final discussion period, it was agreed that: (1) no analytical capability exists to simulate subject conditions; (2) mechanisms reflected by opalescence, the solubility of gases, other interfacial phenomena listed, and fluorescence diagnostics are new and important; (3) multicomponent mixtures, radiation, critical fluctuation, and other recorded ones pose unknown effects; and (4) various identified analytical and experimental actions must be initiated in a mutually supporting sequence.

Throttle pneumatic impact mechanism equipped with afterburner idle-stroke chamber

NASA Astrophysics Data System (ADS)

Dedov, Alexey; Frantseva, Eleanor; Dmitriev, Mikhail

2017-01-01

Pneumatic impact mechanisms are widely used in construction, mining and other economic sectors of a country. Such mechanisms are a base for a wide range of machines of various types and dimensions from hand-held tools to mounted piling hammers with impact energy up to 10 000 J. This paper is aimed at creation of pneumatic impact mechanism with the improved characteristics, including operation, energy use, weight and size which is especially important in space-limited working conditions. The research methods include development of computer mathematical model that can solve equations system and test a prototype model at the experimental stand. As a result of conducted research the pneumatic impact mechanism with the improved characteristics was developed. An engineering method for calculating throttle pneumatic impact mechanisms with a preset value of impact energy from 1 to 20 000 was investigated. This method allows creating percussive machines of a wide range of application.

Space Shuttle Main Engine (SSME) LOX turbopump pump-end bearing analysis

NASA Technical Reports Server (NTRS)

1986-01-01

A simulation of the shaft/bearing system of the Space Shuttle Main Engine Liquid Oxygen turbopump was developed. The simulation model allows the thermal and mechanical characteristics to interact as a realistic simulation of the bearing operating characteristics. The model accounts for single and two phase coolant conditions, and includes the heat generation from bearing friction and fluid stirring. Using the simulation model, parametric analyses were performed on the 45 mm pump-end bearings to investigate the sensitivity of bearing characteristics to contact friction, axial preload, coolant flow rate, coolant inlet temperature and quality, heat transfer coefficients, outer race clearance and misalignment, and the effects of thermally isolating the outer race from the isolator.

Flutter parametric studies of cantilevered twin-engine-transport type wing with and without winglet. Volume 1: Low-speed investigations

NASA Technical Reports Server (NTRS)

Bhatia, K. G.; Nagaraja, K. S.

1984-01-01

Flutter characteristics of a cantilevered high aspect ratio wing with winglet were investigated. The configuration represented a current technology, twin-engine airplane. A low-speed and high-speed model were used to evaluate compressibility effects through transonic Mach numbers and a wide range of mass-density ratios. Four flutter mechanisms were obtained in test, as well as analysis from various combinations of configuration parameters. The coupling between wing tip vertical and chordwise motions was shown to have significant effect under some conditions. It is concluded that for the flutter model configurations studied, the winglet related flutter was amenable to the conventional flutter analysis techniques.

UV Spectroradiometric Output Of An F404 Turbojet Aircraft Engine

NASA Astrophysics Data System (ADS)

Schneider, William E.; Spaberg, Gordon H.

1989-09-01

Spectroradiometric measurements of the ultraviolet output of a GE F404 aircraft engine were made over the wavelength range of 200 to 320 nm. The tests were conducted at the GE Lynn, Mass. Riverworks facility in the F404 ram cell. The severe environmental conditions associated with the test cell required a special acoustical noise-proof and mechanical shock-proof enclosure for the double monochromator and UV detectors along with special long cabling to the externally located radiometer and automatic data reduction system. The tests successfully provided spectral irradiance measurements of the afterburner over the 225-320 nm wavelength range with a UV-enhanced silicon detector and over the 200-260 nm range with a PMT detector.

Monitoring the effect of mechanical stress on mesenchymal stem cell collagen production by multiphoton microscopy

NASA Astrophysics Data System (ADS)

Chen, Wei-Liang; Chang, Chia-Cheng; Chiou, Ling-Ling; Li, Tsung-Hsien; Liu, Yuan; Lee, Hsuan-Shu; Dong, Chen-Yuan

2008-02-01

Tissue engineering is emerging as a promising method for repairing damaged tissues. Due to cartilage's common wear and injury, in vitro production of cartilage replacements have been an active area of research. Finding the optimal condition for the generation of the collagen matrix is crucial in reproducing cartilages that closely match those found in human. Using multiphoton autofluorescence and second-harmonic generation (SHG) microscopy we monitored the effect of mechanical stress on mesenchymal stem cell collagen production. Bone marrow mesenchymal stem cells in the form of pellets were cultured and periodically placed under different mechanical stress by centrifugation over a period of four weeks. The differently stressed samples were imaged several times during the four week period, and the collagen production under different mechanical stress is characterized.

Mechanical Properties and Real-Time Damage Evaluations of Environmental Barrier Coated SiC/SiC CMCs Subjected to Tensile Loading Under Thermal Gradients

NASA Technical Reports Server (NTRS)

Appleby, Matthew; Zhu, Dongming; Morscher, Gregory

2015-01-01

SiC/SiC ceramic matrix composites (CMCs) require new state-of-the art environmental barrier coatings (EBCs) to withstand increased temperature requirements and high velocity combustion corrosive combustion gasses. The present work compares the response of coated and uncoated SiC/SiC CMC substrates subjected to simulated engine environments followed by high temperature mechanical testing to asses retained properties and damage mechanisms. Our focus is to explore the capabilities of electrical resistance (ER) measurements as an NDE technique for testing of retained properties under combined high heat-flux and mechanical loading conditions. Furthermore, Acoustic Emission (AE) measurements and Digital Image Correlation (DIC) were performed to determine material damage onset and accumulation.

Standardized Curriculum for Outboard Marine Engine Mechanics.

ERIC Educational Resources Information Center

Mississippi State Dept. of Education, Jackson. Office of Vocational, Technical and Adult Education.

This curriculum guide for outboard marine engine mechanics was developed by the state of Mississippi to standardize vocational education course titles and core contents. The objectives contained in this document are common to all outboard marine engine mechanics programs in the state. The guide contains objectives for outboard marine engine…

46 CFR 113.35-13 - Mechanical engine order telegraph systems; operation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Mechanical engine order telegraph systems; operation. 113.35-13 Section 113.35-13 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED...-13 Mechanical engine order telegraph systems; operation. If more than one transmitter operates a...

77 FR 39996 - Department of Mechanical Engineering, Texas A&M University, Notice of Decision on Application for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-06

... DEPARTMENT OF COMMERCE International Trade Administration Department of Mechanical Engineering, Texas A&M University, Notice of Decision on Application for Duty-Free Entry of Scientific Instruments...: Department of Mechanical Engineering, Texas A&M University, College Station, TX 77843-3123. Instrument: Arc...

Dr. Johney Green Jr. - Associate Laboratory Director for Mechanical and

Science.gov Websites

Thermal Engineering Sciences | NREL Dr. Johney Green Jr. - Associate Laboratory Director for Mechanical and Thermal Engineering Sciences Dr. Johney Green Jr. - Associate Laboratory Director for Mechanical and Thermal Engineering Sciences A photo of Johney Green In his role, Johney Green oversees early

Experimental study of thermo-mechanical behavior of a thermosetting shape-memory polymer

NASA Astrophysics Data System (ADS)

Liu, Ruoxuan; Li, Yunxin; Liu, Zishun

2018-01-01

The thermo-mechanical behavior of shape-memory polymers (SMPs) serves for the engineering applications of SMPs. Therefore the understanding of thermo-mechanical behavior of SMPs is of great importance. This paper investigates the influence of loading rate and loading level on the thermo-mechanical behavior of a thermosetting shape-memory polymer through experimental study. A series of cyclic tension tests and shape recovery tests at different loading conditions are performed to study the strain level and strain rate effect. The results of tension tests show that the thermosetting shape-memory polymer will behave as rubber material at temperature lower than the glass transition temperature (Tg) and it can obtain a large shape fix ratio at cyclic loading condition. The shape recovery tests exhibit that loading rate and loading level have little effect on the beginning and ending of shape recovery process of the thermosetting shape-memory polymer. Compared with the material which is deformed at temperature higher than Tg, the material deformed at temperature lower than Tg behaves a bigger recovery speed.

On-road and wind-tunnel measurement of motorcycle helmet noise.

PubMed

Kennedy, J; Carley, M; Walker, I; Holt, N

2013-09-01

The noise source mechanisms involved in motorcycling include various aerodynamic sources and engine noise. The problem of noise source identification requires extensive data acquisition of a type and level that have not previously been applied. Data acquisition on track and on road are problematic due to rider safety constraints and the portability of appropriate instrumentation. One way to address this problem is the use of data from wind tunnel tests. The validity of these measurements for noise source identification must first be demonstrated. In order to achieve this extensive wind tunnel tests have been conducted and compared with the results from on-track measurements. Sound pressure levels as a function of speed were compared between on track and wind tunnel tests and were found to be comparable. Spectral conditioning techniques were applied to separate engine and wind tunnel noise from aerodynamic noise and showed that the aerodynamic components were equivalent in both cases. The spectral conditioning of on-track data showed that the contribution of engine noise to the overall noise is a function of speed and is more significant than had previously been thought. These procedures form a basis for accurate experimental measurements of motorcycle noise.

Monitoring tissue formation and organization of engineered tendon by optical coherence tomography

NASA Astrophysics Data System (ADS)

Bagnaninchi, P. O.; Yang, Y.; Maffulli, N.; Wang, R. K.; El Haj, A.

2006-02-01

The uniaxial orientation and bundle formation of collagen fibres determine the mechanical properties of tendons. Thus the particular challenge of tendon tissue engineering is to build the tissue with a highly organized structure of collagen fibres. Ultimately the engineered construct will be used as autologous grafts in tendon surgery, withstanding physiological loading. We grew pig tenocytes in porous chitosan scaffolds with multiple microchannels of 250-500 μm. The cell proliferation and production of extra-cellular matrix (ECM) within the scaffolds have been successfully monitored by Optical Coherence Tomography (OCT), a bench-top OCT system equipped with a broadband light source centred at 1300 nm. Under sterile condition, the measurements were performed on-line and in a non-destructive manner. In addition, a novel method based on OCT imaging, which calculates the occupation ratio of the microchannel derived from the scattered intensity has been developed. It is confirmed that the occupation ratio is correlated to cell proliferation and ECM production in the scaffolds. Thus this method has been utilised to assess the effect of different culture conditions on the tissue formation. The use of a perfusion bioreactor has resulted in a significantly (p<1e -3) higher cell proliferation and matrix production.

Design features of fans, blowers, and compressors

NASA Astrophysics Data System (ADS)

Cheremisinoff, N. P.; Cheremisinoff, P. N.

Fan engineering and compression machines are discussed. Basic aspects of fan performance and design are reviewed, and the design and performance characteristics of radial-flow fans, axial-flow fans, and controllable pitch fans are examined in detail. Air-conditioning systems are discussed, and noise, vibration, and mechanical considerations in fans are extensively examined. The thermodynamic principles governing compression machines are reviewed, and piston compressors, rotary compressors, blowers, and centrifugal compressors are discussed.

Expedition 10 Preflight

NASA Image and Video Library

2004-10-07

Expedition 10 Commander Leroy Chiao undergoes physical testing on a mechanized tilt table at crew quarters in Baikonur, Kazakhstan, Friday, October 8, 2004, in preparation for launch with Flight Engineer and Soyuz Commander Salizhan Sharipov and Russian Space Forces Agency cosmonaut Yuri Shargin to the International Space Station on October 14. The tilt table is used to condition the crewmembers' cardiovascular system against the effects of weightlessness once on orbit. Photo Credit: (NASA/Bill Ingalls)

Expedition 10 Preflight

NASA Image and Video Library

2004-10-07

Expedition 10 Commander Leroy Chiao, left, and Russian Space Forces cosmonaut Yuri Shargin undergo physical testing on a mechanized tilt table at their crew quarters in Baikonur, Kazakhstan, Friday, October 8, 2004, in preparation for launch with Flight Engineer and Soyuz Commander Salizhan Sharipov to the International Space Station on October 14. The tilt table is used to condition the crewmembers' cardiovascular system against the effects of weightlessness once in orbit. Photo Credit: (NASA/Bill Ingalls)

Towards Direct Simulations of Counterflow Flames with Consistent Differential-Algebraic Boundary Conditions

DTIC Science & Technology

2015-01-05

Mechanical and Civil Engineering Dept., California Institute of Technology, Pasadena, CA 91125, USA Josette Bellan † Jet Propulsion Laboratory...91125, USA Kenneth Harstad ‡ Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109, USA A new approach for the formulation of...BDF (Backward Differentiation Formula ), in fixed-leading-coefficient form where the or- der of the method varies between 1 and 5. The BDF method can

Ottawa Sand for Mechanics of Granular Materials (MGM) Experiment

NASA Technical Reports Server (NTRS)

2000-01-01

What appear to be boulders fresh from a tumble down a mountain are really grains of Ottawa sand, a standard material used in civil engineering tests and also used in the Mechanics of Granular Materials (MGM) experiment. The craggy surface shows how sand grans have faces that can cause friction as they roll and slide against each other, or even causing sticking and form small voids between grains. This complex behavior can cause soil to behave like a liquid under certain conditions such as earthquakes or when powders are handled in industrial processes. MGM uses the microgravity of space to simulate this behavior under conditions that carnot be achieved in laboratory tests on Earth. MGM is shedding light on the behavior of fine-grain materials under low effective stresses. Applications include earthquake engineering, granular flow technologies (such as powder feed systems for pharmaceuticals and fertilizers), and terrestrial and planetary geology. Nine MGM specimens have flown on two Space Shuttle flights. Another three are scheduled to fly on STS-107. The principal investigator is Stein Sture of the University of Colorado at Boulder. These images are from an Electron Spectroscopy for Chemical Analysis (ESCA) study conducted by Dr. Binayak Panda of IITRI for Marshall Space Flight Center (MSFC). (Credit: NASA/MSFC)

Compendium of fracture mechanics problems

NASA Technical Reports Server (NTRS)

Stallworth, R.; Wilson, C.; Meyers, C.

1990-01-01

Fracture mechanics analysis results are presented from the following structures/components analyzed at Marshall Space Flight Center (MSFC) between 1982 and 1989: space shuttle main engine (SSME), Hubble Space Telescope (HST), external tank attach ring, B-1 stand LOX inner tank, and solid rocket booster (SRB). Results from the SSME high pressure fuel turbopump (HPFTP) second stage blade parametric analysis determine a critical flaw size for a wide variety of stress intensity values. The engine 0212 failure analysis was a time dependent fracture life assessment. Results indicated that the disk ruptured due to an overspeed condition. Results also indicated that very small flaws in the curvic coupling area could propagate and lead to failure under normal operating conditions. It was strongly recommended that a nondestructive evaluation inspection schedule be implemented. The main ring of the HST, scheduled to launch in 1990, was analyzed by safe-life and fail-safe analyses. First safe-life inspection criteria curves for the ring inner and outer skins and the fore and aft channels were derived. Afterwards the skins and channels were determined to be fail-safe by analysis. A conservative safe-life analysis was done on the 270 redesign external tank attach ring. Results from the analysis were used to determine the nondestructive evaluation technique required.

Mechanisms of lamellar collagen formation in connective tissues.

PubMed

Ghazanfari, Samaneh; Khademhosseini, Ali; Smit, Theodoor H

2016-08-01

The objective of tissue engineering is to regenerate functional tissues. Engineering functional tissues requires an understanding of the mechanisms that guide the formation and evolution of structure in the extracellular matrix (ECM). In particular, the three-dimensional (3D) collagen fiber arrangement is important as it is the key structural determinant that provides mechanical integrity and biological function. In this review, we survey the current knowledge on collagen organization mechanisms that can be applied to create well-structured functional lamellar tissues and in particular intervertebral disc and cornea. Thus far, the mechanisms behind the formation of cross-aligned collagen fibers in the lamellar structures is not fully understood. We start with cell-induced collagen alignment and strain-stabilization behavior mechanisms which can explain a single anisotropically aligned collagen fiber layer. These mechanisms may explain why there is anisotropy in a single layer in the first place. However, they cannot explain why a consecutive collagen layer is laid down with an alternating alignment. Therefore, we explored another mechanism, called liquid crystal phasing. While dense concentrations of collagen show such behavior, there is little evidence that the conditions for liquid crystal phasing are actually met in vivo. Instead, lysyl aldehyde-derived collagen cross-links have been found essential for correct lamellar matrix deposition. Furthermore, we suggest that supra-cellular (tissue-level) shear stress may be instrumental in the alignment of collagen fibers. Understanding the potential mechanisms behind the lamellar collagen structure in connective tissues will lead to further improvement of the regeneration strategies of functional complex lamellar tissues. Copyright © 2016 Elsevier Ltd. All rights reserved.

46 CFR 12.607 - Requirements to qualify for an STCW endorsement as rating as able seafarer-engine.

Code of Federal Regulations, 2014 CFR

2014-10-01

... mechanic, or engineman in the engine department, or as an RFPEW for a period of not less than 12 months... Engineman None. Deck Engine Mechanic None. Electrician 6 months.1 Refrigerating Engineer 6 months.1 Pumpman...

Two-Year ET Programs: Essential Topics and Levels of Proficiency.

ERIC Educational Resources Information Center

Gourley, Frank A., Jr.

1990-01-01

Reports the results of a survey of graduates, employers, and instructors of engineering technology programs for the essential topics in mechanical engineering technology, mechanical drafting/design technology, manufacturing engineering technology, and industrial engineering technology. Identifies the proficiency level suggested for classwork and…

Smart actuation of inlet guide vanes for small turbine engine

NASA Astrophysics Data System (ADS)

Rusovici, Razvan; Kwok Choon, Stephen T.; Sepri, Paavo; Feys, Joshuo

2011-04-01

Unmanned Aerial Vehicles (UAVs) have gained popularity over the past few years to become an indispensable part of aerial missions that include reconnaissance, surveillance, and communication [1]. As a result, advancements in small jet-engine performance are needed to increase the performance (range, payload and efficiency) of the UAV. These jet engines designed especially for UAV's are characterized by thrust force on the order of 100N and due to their size and weight limitations, may lack advanced flow control devices such as IGV [2]. The goal of the current study was to present a conceptual design of an IGV smart-material based actuation mechanism that would be simple, compact and lightweight. The compressor section of an engine increases the pressure and conditions the flow before the air enters the combustion chamber [3]. The airflow entering the compressor is often turbulent due to the high angle of incidence between engine inlet and free-stream velocity, or existing atmospheric turbulence. Actuated IGV are used to help control the relative angle of incidence of the flow that enters the engine compressor, thereby preventing flow separation, compressor stall and thus extending the compressor's operating envelope [4]. Turbine jet- engines which employ variable IGV were developed by Rolls Royce (Trent DR-900) and General Electric (J79).

High-fidelity simulations of a standing-wave thermoacoustic-piezoelectric engine

NASA Astrophysics Data System (ADS)

Lin, Jeffrey; Scalo, Carlo; Hesselink, Lambertus

2014-11-01

We have carried out time-domain three-dimensional and one-dimensional numerical simulations of a thermoacoustic Stirling heat engine (TASHE). The TASHE model adopted for our study is that of a standing-wave engine: a thermal gradient is imposed in a resonator tube and is capped with a piezoelectric diaphragm in a Helmholtz resonator cavity for acoustic energy extraction. The 0.51 m engine sustains 500 Pa pressure oscillations with atmospheric air and pressure. Such an engine is interesting in practice as an external heat engine with no mechanically-moving parts. Our numerical setup allows for both the evaluation of the nonlinear effects of scaling and the effect of a fully electromechanically-coupled impedance boundary condition, representative of a piezoelectric element. The thermoacoustic stack is fully resolved. Previous modeling efforts have focused on steady-state solvers with impedances or nonlinear effects without energy extraction. Optimization of scaling and the impedance for power output can now be simultaneously applied; engines of smaller sizes and higher frequencies suitable for piezoelectric energy extraction can be studied with three-dimensional solvers without restriction. Results at a low-amplitude regime were validated against results obtained from the steady-state solver DeltaEC and from experimental results in literature. Pressure and velocity amplitudes within the cavities match within 2% difference.

Ecosystem engineering affects ecosystem functioning in high-Andean landscapes.

PubMed

Badano, Ernesto I; Marquet, Pablo A

2008-04-01

Ecosystem engineers are organisms that change the distribution of materials and energy in the abiotic environment, usually creating and maintaining new habitat patches in the landscape. Such changes in habitat conditions have been widely documented to affect the distributions and performances of other species but up to now no studies have addressed how such effects can impact the biotically driven physicochemical processes associated with these landscapes, or ecosystem functions. Based on the widely accepted positive relationship between species diversity and ecosystem functions, we propose that the effects of ecosystem engineers on other species could have an impact on ecosystem functions via two mutually inclusive mechanisms: (1) by adding new species into landscapes, hence increasing species diversity; and (2) by improving the performances of species already present in the landscape. To test these hypotheses, we focused on the effects of a high-Andean ecosystem engineer, the cushion plant Azorella monantha, by comparing the accumulation of plant biomass and nitrogen fixed in plant tissues as species richness increases in landscapes with and without the engineer species. Our results show that both ecosystem functions increased with species richness in both landscape types, but landscapes including A. monantha cushions reached higher outcomes of plant biomass and nitrogen fixed in plant tissues than landscapes without cushions. Moreover, our results indicate that such positive effects on ecosystem functions could be mediated by the two mechanisms proposed above. Then, given the conspicuousness of ecosystem engineering in nature and its strong influence on species diversity, and given the well-known relationship between species diversity and ecosystem function, we suggest that the application of the conceptual framework proposed herein to other ecosystems would help to advance our understanding of the forces driving ecosystem functioning.

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model.

PubMed

Lee-Barthel, Ann; Baar, Keith; West, Daniel W D

2017-06-11

In vitro experiments are essential to understand biological mechanisms; however, the gap between monolayer tissue culture and human physiology is large, and translation of findings is often poor. Thus, there is ample opportunity for alternative experimental approaches. Here we present an approach in which human cells are isolated from human anterior cruciate ligament tissue remnants, expanded in culture, and used to form engineered ligaments. Exercise alters the biochemical milieu in the blood such that the function of many tissues, organs and bodily processes are improved. In this experiment, ligament construct culture media was supplemented with experimental human serum that has been 'conditioned' by exercise. Thus the intervention is more biologically relevant since an experimental tissue is exposed to the full endogenous biochemical milieu, including binding proteins and adjunct compounds that may be altered in tandem with the activity of an unknown agent of interest. After treatment, engineered ligaments can be analyzed for mechanical function, collagen content, morphology, and cellular biochemistry. Overall, there are four major advantages versus traditional monolayer culture and animal models, of the physiological model of ligament tissue that is presented here. First, ligament constructs are three-dimensional, allowing for mechanical properties (i.e., function) such as ultimate tensile stress, maximal tensile load, and modulus, to be quantified. Second, the enthesis, the interface between boney and sinew elements, can be examined in detail and within functional context. Third, preparing media with post-exercise serum allows for the effects of the exercise-induced biochemical milieu, which is responsible for the wide range of health benefits of exercise, to be investigated in an unbiased manner. Finally, this experimental model advances scientific research in a humane and ethical manner by replacing the use of animals, a core mandate of the National Institutes of Health, the Center for Disease Control, and the Food and Drug Administration.

Developing a Virtual Rock Deformation Laboratory

NASA Astrophysics Data System (ADS)

Zhu, W.; Ougier-simonin, A.; Lisabeth, H. P.; Banker, J. S.

2012-12-01

Experimental rock physics plays an important role in advancing earthquake research. Despite its importance in geophysics, reservoir engineering, waste deposits and energy resources, most geology departments in U.S. universities don't have rock deformation facilities. A virtual deformation laboratory can serve as an efficient tool to help geology students naturally and internationally learn about rock deformation. Working with computer science engineers, we built a virtual deformation laboratory that aims at fostering user interaction to facilitate classroom and outreach teaching and learning. The virtual lab is built to center around a triaxial deformation apparatus in which laboratory measurements of mechanical and transport properties such as stress, axial and radial strains, acoustic emission activities, wave velocities, and permeability are demonstrated. A student user can create her avatar to enter the virtual lab. In the virtual lab, the avatar can browse and choose among various rock samples, determine the testing conditions (pressure, temperature, strain rate, loading paths), then operate the virtual deformation machine to observe how deformation changes physical properties of rocks. Actual experimental results on the mechanical, frictional, sonic, acoustic and transport properties of different rocks at different conditions are compiled. The data acquisition system in the virtual lab is linked to the complied experimental data. Structural and microstructural images of deformed rocks are up-loaded and linked to different deformation tests. The integration of the microstructural image and the deformation data allows the student to visualize how forces reshape the structure of the rock and change the physical properties. The virtual lab is built using the Game Engine. The geological background, outstanding questions related to the geological environment, and physical and mechanical concepts associated with the problem will be illustrated on the web portal. In addition, some web based data collection tools are available to collect student feedback and opinions on their learning experience. The virtual laboratory is designed to be an online education tool that facilitates interactive learning.; Virtual Deformation Laboratory

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model

PubMed Central

Lee-Barthel, Ann; Baar, Keith; West, Daniel W. D.

2017-01-01

In vitro experiments are essential to understand biological mechanisms; however, the gap between monolayer tissue culture and human physiology is large, and translation of findings is often poor. Thus, there is ample opportunity for alternative experimental approaches. Here we present an approach in which human cells are isolated from human anterior cruciate ligament tissue remnants, expanded in culture, and used to form engineered ligaments. Exercise alters the biochemical milieu in the blood such that the function of many tissues, organs and bodily processes are improved. In this experiment, ligament construct culture media was supplemented with experimental human serum that has been 'conditioned' by exercise. Thus the intervention is more biologically relevant since an experimental tissue is exposed to the full endogenous biochemical milieu, including binding proteins and adjunct compounds that may be altered in tandem with the activity of an unknown agent of interest. After treatment, engineered ligaments can be analyzed for mechanical function, collagen content, morphology, and cellular biochemistry. Overall, there are four major advantages versus traditional monolayer culture and animal models, of the physiological model of ligament tissue that is presented here. First, ligament constructs are three-dimensional, allowing for mechanical properties (i.e., function) such as ultimate tensile stress, maximal tensile load, and modulus, to be quantified. Second, the enthesis, the interface between boney and sinew elements, can be examined in detail and within functional context. Third, preparing media with post-exercise serum allows for the effects of the exercise-induced biochemical milieu, which is responsible for the wide range of health benefits of exercise, to be investigated in an unbiased manner. Finally, this experimental model advances scientific research in a humane and ethical manner by replacing the use of animals, a core mandate of the National Institutes of Health, the Center for Disease Control, and the Food and Drug Administration. PMID:28654031

49 CFR 173.220 - Internal combustion engines, self-propelled vehicles, mechanical equipment containing internal...

Code of Federal Regulations, 2010 CFR

2010-10-01

... vehicles, mechanical equipment containing internal combustion engines, and battery powered vehicles or... equipment containing internal combustion engines, and battery powered vehicles or equipment. (a... internal combustion engine, or a battery powered vehicle or equipment is subject to the requirements of...

Table-Top Robotics for Engineering Design

ERIC Educational Resources Information Center

Wilczynski, Vincent; Dixon, Gregg; Ford, Eric

2005-01-01

The Mechanical Engineering Section at the U.S. Coast Guard Academy has developed a comprehensive activity based course to introduce second year students to mechanical engineering design. The culminating design activity for the course requires students to design, construct and test robotic devices that complete engineering challenges. Teams of…

Shawn Sheng | NREL

Science.gov Websites

experience includes mechanical and electrical system modeling and analysis, data sensing and sensor placement . Education Ph.D. in Mechanical Engineering, University of Massachusetts at Amherst; M.S. in Electrical Engineering, Institute of Electrical Engineering, Chinese Academy of Sciences; B.S. in Electrical Engineering

Mechanical Behavior of Advanced Materials for Aerospace Applications

NASA Technical Reports Server (NTRS)

Telesman, Ignancy (Technical Monitor); Kantzos, Peter; Shannon, Brian

2003-01-01

The purpose of this study was to determine whether High Cycle Fatigue (HCF) loading has any deleterious synergistic effect on life when combined with the typical Low Cycle Fatigue (LCF) loading present in engine disks. This interaction is particularly important in the rim region of blisk applications, where fatigue initiations from vibratory stresses (HCF) may be propagated to the disk by LCF. The primary effort in this study was focused on determining and documenting initiation sites and damage mechanisms. Under LCF loading conditions the failures were predominantly surface initiated, while HCF loading favored internal initiations. Deleterious HCF/LCF interactions would always result in a transition from internal to surface initiations. The results indicated that under the relative stress conditions evaluated there was no interaction between HCF and LCF. In FY99 this effort was extended to investigate several other loading conditions (R-ratio effects) as well as interactions between LCF and two-hour tensile dwells. The results will be published as a NASA Technical Memorandum.

Meso-Scale Finite Element Analysis of Mechanical Behavior of 3D Braided Composites Subjected to Biaxial Tension Loadings

NASA Astrophysics Data System (ADS)

Zhang, Chao; Curiel-Sosa, Jose L.; Bui, Tinh Quoc

2018-04-01

In many engineering applications, 3D braided composites are designed for primary loading-bearing structures, and they are frequently subjected to multi-axial loading conditions during service. In this paper, a unit-cell based finite element model is developed for assessment of mechanical behavior of 3D braided composites under different biaxial tension loadings. To predict the damage initiation and evolution of braiding yarns and matrix in the unit-cell, we thus propose an anisotropic damage model based on Murakami damage theory in conjunction with Hashin failure criteria and maximum stress criteria. To attain exact stress ratio, force loading mode of periodic boundary conditions which never been attempted before is first executed to the unit-cell model to apply the biaxial tension loadings. The biaxial mechanical behaviors, such as the stress distribution, tensile modulus and tensile strength are analyzed and discussed. The damage development of 3D braided composites under typical biaxial tension loadings is simulated and the damage mechanisms are revealed in the simulation process. The present study generally provides a new reference to the meso-scale finite element analysis (FEA) of multi-axial mechanical behavior of other textile composites.

Structural Noise and Acoustic Characteristics Improvement of Transport Power Plants

NASA Astrophysics Data System (ADS)

Chaynov, N. D.; Markov, V. A.; Savastenko, A. A.

2018-03-01

Noise reduction generated during the operation of various machines and mechanisms is an urgent task with regard to the power plants and, in particular, to internal combustion engines. Sound emission from the surfaces vibration of body parts is one of the main noise manifestations of the running engine and it is called a structural noise. The vibration defining of the outer surfaces of complex body parts and the calculation of their acoustic characteristics are determined with numerical methods. At the same time, realization of finite and boundary elements methods combination turned out to be very effective. The finite element method is used in calculating the structural elements vibrations, and the boundary elements method is used in the structural noise calculation. The main conditions of the methodology and the results of the structural noise analysis applied to a number of automobile engines are shown.

Duct flow nonuniformities study for space shuttle main engine

NASA Technical Reports Server (NTRS)

Thoenes, J.

1985-01-01

To improve the Space Shuttle Main Engine (SSME) design and for future use in the development of generation rocket engines, a combined experimental/analytical study was undertaken with the goals of first, establishing an experimental data base for the flow conditions in the SSME high pressure fuel turbopump (HPFTP) hot gas manifold (HGM) and, second, setting up a computer model of the SSME HGM flow field. Using the test data to verify the computer model it should be possible in the future to computationally scan contemplated advanced design configurations and limit costly testing to the most promising design. The effort of establishing and using the computer model is detailed. The comparison of computational results and experimental data observed clearly demonstrate that computational fluid mechanics (CFD) techniques can be used successfully to predict the gross features of three dimensional fluid flow through configurations as intricate as the SSME turbopump hot gas manifold.

Through the Google Goggles: Sociopolitical Bias in Search Engine Design

NASA Astrophysics Data System (ADS)

Diaz, A.

Search engines like Google are essential to navigating the Web's endless supply of news, political information, and citizen discourse. The mechanisms and conditions under which search results are selected should therefore be of considerable interest to media scholars, political theorists, and citizens alike. In this chapter, I adopt a "deliberative" ideal for search engines and examine whether Google exhibits the "same old" media biases of mainstreaming, hypercommercialism, and industry consolidation. In the end, serious objections to Google are raised: Google may favor popularity over richness; it provides advertising that competes directly with "editorial" content; it so overwhelmingly dominates the industry that users seldom get a second opinion, and this is unlikely to change. Ultimately, however, the results of this analysis may speak less about Google than about contradictions in the deliberative ideal and the so-called "inherently democratic" nature of the Web.

Results of an Advanced Fan Stage Operating Over a Wide Range of Speed and Bypass Ratio. Part 2; Comparison of CFD and Experimental Results

NASA Technical Reports Server (NTRS)

Celestina, Mark L.; Suder, Kenneth L.; Kulkarni, Sameer

2010-01-01

NASA and GE teamed to design and build a 57 percent engine scaled fan stage for a Mach 4 variable cycle turbofan/ramjet engine for access to space with multipoint operations. This fan stage was tested in NASA's transonic compressor facility. The objectives of this test were to assess the aerodynamic and aero mechanic performance and operability characteristics of the fan stage over the entire range of engine operation including: 1) sea level static take-off; 2) transition over large swings in fan bypass ratio; 3) transition from turbofan to ramjet; and 4) fan wind-milling operation at high Mach flight conditions. This paper will focus on an assessment of APNASA, a multistage turbomachinery analysis code developed by NASA, to predict the fan stage performance and operability over a wide range of speeds (37 to 100 percent) and bypass ratios.

Australian Apprentice & Trainee Statistics: Mechanical Engineering and Fabrication Trades, 1995-1999. Australian Vocational Education & Training.

ERIC Educational Resources Information Center

National Centre for Vocational Education Research, Leabrook (Australia).

Statistics regarding Australians participating in apprenticeships and traineeships in the mechanical engineering and fabrication trades in 1995-1999 were reviewed to provide an indication of where skill shortages may be occurring or will likely occur in relation to the following occupations: mechanical engineering trades; fabrication engineering…

Selection of software for mechanical engineering undergraduates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cheah, C. T.; Yin, C. S.; Halim, T.

A major problem with the undergraduate mechanical course is the limited exposure of students to software packages coupled with the long learning curve on the existing software packages. This work proposes the use of appropriate software packages for the entire mechanical engineering curriculum to ensure students get sufficient exposure real life design problems. A variety of software packages are highlighted as being suitable for undergraduate work in mechanical engineering, e.g. simultaneous non-linear equations; uncertainty analysis; 3-D modeling software with the FEA; analysis tools for the solution of problems in thermodynamics, fluid mechanics, mechanical system design, and solid mechanics.

Evolutionary engineering reveals divergent paths when yeast is adapted to different acidic environments.

PubMed

Fletcher, Eugene; Feizi, Amir; Bisschops, Markus M M; Hallström, Björn M; Khoomrung, Sakda; Siewers, Verena; Nielsen, Jens

2017-01-01

Tolerance of yeast to acid stress is important for many industrial processes including organic acid production. Therefore, elucidating the molecular basis of long term adaptation to acidic environments will be beneficial for engineering production strains to thrive under such harsh conditions. Previous studies using gene expression analysis have suggested that both organic and inorganic acids display similar responses during short term exposure to acidic conditions. However, biological mechanisms that will lead to long term adaptation of yeast to acidic conditions remains unknown and whether these mechanisms will be similar for tolerance to both organic and inorganic acids is yet to be explored. We therefore evolved Saccharomyces cerevisiae to acquire tolerance to HCl (inorganic acid) and to 0.3M L-lactic acid (organic acid) at pH 2.8 and then isolated several low pH tolerant strains. Whole genome sequencing and RNA-seq analysis of the evolved strains revealed different sets of genome alterations suggesting a divergence in adaptation to these two acids. An altered sterol composition and impaired iron uptake contributed to HCl tolerance whereas the formation of a multicellular morphology and rapid lactate degradation was crucial for tolerance to high concentrations of lactic acid. Our findings highlight the contribution of both the selection pressure and nature of the acid as a driver for directing the evolutionary path towards tolerance to low pH. The choice of carbon source was also an important factor in the evolutionary process since cells evolved on two different carbon sources (raffinose and glucose) generated a different set of mutations in response to the presence of lactic acid. Therefore, different strategies are required for a rational design of low pH tolerant strains depending on the acid of interest. Copyright © 2016 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.

The role of environmental factors in regulating the development of cartilaginous grafts engineered using osteoarthritic human infrapatellar fat pad-derived stem cells.

PubMed

Liu, Yurong; Buckley, Conor T; Downey, Richard; Mulhall, Kevin J; Kelly, Daniel J

2012-08-01

Engineering functional cartilaginous grafts using stem cells isolated from osteoarthritic human tissue is of fundamental importance if autologous tissue engineering strategies are to be used in the treatment of diseased articular cartilage. It has previously been demonstrated that human infrapatellar fat pad (IFP)-derived stem cells undergo chondrogenesis in pellet culture; however, the ability of such cells to generate functional cartilaginous grafts has not been adequately addressed. The objective of this study was to explore how environmental conditions regulate the functional development of cartilaginous constructs engineered using diseased human IFP-derived stem cells (FPSCs). FPSCs were observed to display a diminished chondrogenic potential upon encapsulation in a three-dimensional hydrogel compared with pellet culture, synthesizing significantly lower levels of glycosaminoglycan and collagen on a per cell basis. To engineer more functional cartilaginous grafts, we next explored whether additional biochemical and biophysical stimulations would enhance chondrogenesis within the hydrogels. Serum stimulation was observed to partially recover the diminished chondrogenic potential within hydrogel culture. Over 42 days, stem cells that had first been expanded in a low-oxygen environment proliferated extensively on the outer surface of the hydrogel in response to serum stimulation, assembling a dense type II collagen-positive cartilaginous tissue resembling that formed in pellet culture. The application of hydrostatic pressure did not further enhance extracellular matrix synthesis within the hydrogels, but did appear to alter the spatial accumulation of extracellular matrix leading to the formation of a more compact tissue with superior mechanically functionality. Further work is required in order to recapitulate the environmental conditions present during pellet culture within scaffolds or hydrogels in order to engineer more functional cartilaginous grafts using human osteoarthritic FPSCs.

Visual Computing Environment

NASA Technical Reports Server (NTRS)

Lawrence, Charles; Putt, Charles W.

1997-01-01

The Visual Computing Environment (VCE) is a NASA Lewis Research Center project to develop a framework for intercomponent and multidisciplinary computational simulations. Many current engineering analysis codes simulate various aspects of aircraft engine operation. For example, existing computational fluid dynamics (CFD) codes can model the airflow through individual engine components such as the inlet, compressor, combustor, turbine, or nozzle. Currently, these codes are run in isolation, making intercomponent and complete system simulations very difficult to perform. In addition, management and utilization of these engineering codes for coupled component simulations is a complex, laborious task, requiring substantial experience and effort. To facilitate multicomponent aircraft engine analysis, the CFD Research Corporation (CFDRC) is developing the VCE system. This system, which is part of NASA's Numerical Propulsion Simulation System (NPSS) program, can couple various engineering disciplines, such as CFD, structural analysis, and thermal analysis. The objectives of VCE are to (1) develop a visual computing environment for controlling the execution of individual simulation codes that are running in parallel and are distributed on heterogeneous host machines in a networked environment, (2) develop numerical coupling algorithms for interchanging boundary conditions between codes with arbitrary grid matching and different levels of dimensionality, (3) provide a graphical interface for simulation setup and control, and (4) provide tools for online visualization and plotting. VCE was designed to provide a distributed, object-oriented environment. Mechanisms are provided for creating and manipulating objects, such as grids, boundary conditions, and solution data. This environment includes parallel virtual machine (PVM) for distributed processing. Users can interactively select and couple any set of codes that have been modified to run in a parallel distributed fashion on a cluster of heterogeneous workstations. A scripting facility allows users to dictate the sequence of events that make up the particular simulation.

Possible Mechanisms for Turbofan Engine Ice Crystal Icing at High Altitude

NASA Technical Reports Server (NTRS)

Tsao, Jen-Ching; Struk, Peter M.; Oliver, Michael

2014-01-01

A thermodynamic model is presented to describe possible mechanisms of ice formation on unheated surfaces inside a turbofan engine compression system from fully glaciated ice crystal clouds often formed at high altitude near deep convective weather systems. It is shown from the analysis that generally there could be two distinct types of ice formation: (1) when the "surface freezing fraction" is in the range of 0 to 1, dominated by the freezing of water melt from fully or partially melted ice crystals, the ice structure is formed from accretion with strong adhesion to the surface, and (2) when the "surface melting fraction" is the range of 0 to 1, dominated by the further melting of ice crystals, the ice structure is formed from accumulation of un-melted ice crystals with relatively weak bonding to the surface. The model captures important qualitative trends of the fundamental ice-crystal icing phenomenon reported earlier1,2 from the research collaboration work by NASA and the National Research Council (NRC) of Canada. Further, preliminary analysis of test data from the 2013 full scale turbofan engine ice crystal icing test3 conducted in the NASA Glenn Propulsion Systems Laboratory (PSL) has also suggested that (1) both types of ice formation occurred during the test, and (2) the model has captured some important qualitative trend of turning on (or off) the ice crystal ice formation process in the tested engine low pressure compressor (LPC) targeted area under different icing conditions that ultimately would lead to (or suppress) an engine core roll back (RB) event.

Possible Mechanisms for Turbofan Engine Ice Crystal Icing at High Altitude

NASA Technical Reports Server (NTRS)

Tsao, Jen-Ching; Struk, Peter M.; Oliver, Michael J.

2016-01-01

A thermodynamic model is presented to describe possible mechanisms of ice formation on unheated surfaces inside a turbofan engine compression system from fully glaciated ice crystal clouds often formed at high altitude near deep convective weather systems. It is shown from the analysis that generally there could be two distinct types of ice formation: (1) when the "surface freezing fraction" is in the range of 0 to 1, dominated by the freezing of water melt from fully or partially melted ice crystals, the ice structure is formed from accretion with strong adhesion to the surface, and (2) when the "surface melting fraction" is the range of 0 to 1, dominated by the further melting of ice crystals, the ice structure is formed from accumulation of un-melted ice crystals with relatively weak bonding to the surface. The model captures important qualitative trends of the fundamental ice-crystal icing phenomenon reported earlier (Refs. 1 and 2) from the research collaboration work by NASA and the National Research Council (NRC) of Canada. Further, preliminary analysis of test data from the 2013 full scale turbofan engine ice crystal icing test (Ref. 3) conducted in the NASA Glenn Propulsion Systems Laboratory (PSL) has also suggested that (1) both types of ice formation occurred during the test, and (2) the model has captured some important qualitative trend of turning on (or off) the ice crystal ice formation process in the tested engine low pressure compressor (LPC) targeted area under different icing conditions that ultimately would lead to (or suppress) an engine core roll back (RB) event.

Aircraft Engine Sump Fire Mitigation

NASA Technical Reports Server (NTRS)

Rosenlieb, J. W.

1973-01-01

An investigation was performed of the conditions in which fires can result and be controlled within the bearing sump simulating that of a gas turbine engine; Esso 4040 Turbo Oil, Mobil Jet 2, and Monsanto MCS-2931 lubricants were used. Control variables include the oil inlet temperature, bearing temperature, oil inlet and scavenge rates, hot air inlet temperature and flow rate, and internal sump baffling. In addition to attempting spontaneous combustion, an electric spark and a rub (friction) mechanism were employed to ignite fires. Spontaneous combustion was not obtained; however, fires were readily ignited with the electric spark while using each of the three test lubricants. Fires were also ignited using the rub mechanism with the only test lubricant evaluated, Esso 4040. Major parameters controlling ignitions were: Sump configuration; Bearing and oil temperatures, hot air temperature and flow and bearing speed. Rubbing between stationary parts and rotating parts (eg. labyrinth seal and mating rub strip) is a very potent fire source suggesting that observed accidental fires in gas turbine sumps may well arise from this cause.

Reverse Engineering Applied to Red Human Hair Pheomelanin Reveals Redox-Buffering as a Pro-Oxidant Mechanism

PubMed Central

Kim, Eunkyoung; Panzella, Lucia; Micillo, Raffaella; Bentley, William E.; Napolitano, Alessandra; Payne, Gregory F.

2015-01-01

Pheomelanin has been implicated in the increased susceptibility to UV-induced melanoma for people with light skin and red hair. Recent studies identified a UV-independent pathway to melanoma carcinogenesis and implicated pheomelanin’s pro-oxidant properties that act through the generation of reactive oxygen species and/or the depletion of cellular antioxidants. Here, we applied an electrochemically-based reverse engineering methodology to compare the redox properties of human hair pheomelanin with model synthetic pigments and natural eumelanin. This methodology exposes the insoluble melanin samples to complex potential (voltage) inputs and measures output response characteristics to assess redox activities. The results demonstrate that both eumelanin and pheomelanin are redox-active, they can rapidly (sec-min) and repeatedly redox-cycle between oxidized and reduced states, and pheomelanin possesses a more oxidative redox potential. This study suggests that pheomelanin’s redox-based pro-oxidant activity may contribute to sustaining a chronic oxidative stress condition through a redox-buffering mechanism. PMID:26669666

Reverse Engineering Applied to Red Human Hair Pheomelanin Reveals Redox-Buffering as a Pro-Oxidant Mechanism.

PubMed

Kim, Eunkyoung; Panzella, Lucia; Micillo, Raffaella; Bentley, William E; Napolitano, Alessandra; Payne, Gregory F

2015-12-16

Pheomelanin has been implicated in the increased susceptibility to UV-induced melanoma for people with light skin and red hair. Recent studies identified a UV-independent pathway to melanoma carcinogenesis and implicated pheomelanin's pro-oxidant properties that act through the generation of reactive oxygen species and/or the depletion of cellular antioxidants. Here, we applied an electrochemically-based reverse engineering methodology to compare the redox properties of human hair pheomelanin with model synthetic pigments and natural eumelanin. This methodology exposes the insoluble melanin samples to complex potential (voltage) inputs and measures output response characteristics to assess redox activities. The results demonstrate that both eumelanin and pheomelanin are redox-active, they can rapidly (sec-min) and repeatedly redox-cycle between oxidized and reduced states, and pheomelanin possesses a more oxidative redox potential. This study suggests that pheomelanin's redox-based pro-oxidant activity may contribute to sustaining a chronic oxidative stress condition through a redox-buffering mechanism.

Modern Aspects of Liquid Metal Engineering

NASA Astrophysics Data System (ADS)

Czerwinski, Frank

2017-02-01

Liquid metal engineering (LME) refers to a variety of physical and/or chemical treatments of molten metals aimed at influencing their solidification characteristics. Although the fundamentals have been known for decades, only recent progress in understanding solidification mechanisms has renewed an interest in opportunities this technique creates for an improvement of castings. This review covers conventional and novel concepts of LME with their application to modern manufacturing techniques based not only on liquid but also on semisolid routes. The role of external forces applied to the melt combined with grain nucleation control is explained along with laboratory- and commercial-scale equipment designed for implementation of various concepts exploring mechanical, electromagnetic, and ultrasound principles. An influence of melt treatments on quality of the final product is considered through distinguishing between internal integrity of net shape components and the alloy microstructure. Recent global developments indicate that exploring the synergy of melt chemistry and physical treatments achieved through LME allows creating the optimum conditions for nucleation and growth during solidification, positively affecting quality of castings.

The regimes of twin-fluid jet-in-crossflow at atmospheric and jet-engine operating conditions

NASA Astrophysics Data System (ADS)

Tan, Zu Puayen; Bibik, Oleksandr; Shcherbik, Dmitriy; Zinn, Ben T.; Patel, Nayan

2018-02-01

The "Twin-Fluid Jet-in-Crossflow (TF-JICF)" is a nascent variation of the classical JICF, in which a liquid jet is co-injected with an annular sleeve of gas into a gaseous crossflow. Jet-engine designers are interested in using TF-JICF for liquid-fuel injection and atomization in the next-generation combustors because it is expected to minimize combustor-damaging auto-ignition and fuel-coking tendencies. However, experimental data of TF-JICF are sparse. Furthermore, a widely accepted TF-JICF model that correlates the spray's penetration to the combined liquid-gas momentum-flux ratio (Jeff) is increasingly showing discrepancy with emerging results, suggesting a gap in the current understanding of TF-JICF. This paper describes an investigation that addressed the gap by experimentally characterizing the TF-JICF produced by a single injector across wide ranges of operating conditions (i.e., jet-A injectant, crossflow of air, crossflow Weber number = 175-1050, crossflow pressure Pcf = 1.8-9.5 atm, momentum-flux ratio J = 5-40, and air-nozzle dP = 0%-150% of Pcf). These covered the conditions previously used to develop the Jeff model, recently reported conditions that produced Jeff discrepancies, and high-pressure conditions found in jet-engines. Dye-based shadowgraph was used to acquire high-resolution (13.52 μm/pixel) images of the TF-JICF, which revealed wide-ranging characteristics such as the disrupted Rayleigh-Taylor jet instabilities, air-induced jet corrugations, spray-bifurcations, and prompt-atomization. Analyses of the data showed that contrary to the literature, the TF-JICF's penetration is not monotonically related to Jeff. A new conceptual framework for TF-JICF is proposed, where the flow configuration is composed of four regimes, each having different penetration trends, spray structures, and underlying mechanisms.

Development of Engineering Design Education in the Department of Mechanical Engineering at Kanazawa Technical College

NASA Astrophysics Data System (ADS)

Yamada, Hirofumi; Ten-Nichi, Michio; Mathui, Hirosi; Nakamura, Akizi

This paper introduces a method of the engineering design education for college of technology mechanical engineering students. In order to teach the practical engineering design, the MIL-STD-499A process is adapted and improved upon for a Mechatronics hands-on lesson used as the MOT method. The educational results in five years indicate that knowledge of the engineering management is useful for college students in learning engineering design. Portfolio for lessons and the hypothesis method also have better effects on the understanding of the engineering specialty.

The effects of dynamic compression on the development of cartilage grafts engineered using bone marrow and infrapatellar fat pad derived stem cells.

PubMed

Luo, Lu; Thorpe, Stephen D; Buckley, Conor T; Kelly, Daniel J

2015-09-21

Bioreactors that subject cell seeded scaffolds or hydrogels to biophysical stimulation have been used to improve the functionality of tissue engineered cartilage and to explore how such constructs might respond to the application of joint specific mechanical loading. Whether a particular cell type responds appropriately to physiological levels of biophysical stimulation could be considered a key determinant of its suitability for cartilage tissue engineering applications. The objective of this study was to determine the effects of dynamic compression on chondrogenesis of stem cells isolated from different tissue sources. Porcine bone marrow (BM) and infrapatellar fat pad (FP) derived stem cells were encapsulated in agarose hydrogels and cultured in a chondrogenic medium in free swelling (FS) conditions for 21 d, after which samples were subjected to dynamic compression (DC) of 10% strain (1 Hz, 1 h d(-1)) for a further 21 d. Both BM derived stem cells (BMSCs) and FP derived stem cells (FPSCs) were capable of generating cartilaginous tissues with near native levels of sulfated glycosaminoglycan (sGAG) content, although the spatial development of the engineered grafts strongly depended on the stem cell source. The mechanical properties of cartilage grafts generated from both stem cell sources also approached that observed in skeletally immature animals. Depending on the stem cell source and the donor, the application of DC either enhanced or had no significant effect on the functional development of cartilaginous grafts engineered using either BMSCs or FPSCs. BMSC seeded constructs subjected to DC stained less intensely for collagen type I. Furthermore, histological and micro-computed tomography analysis showed mineral deposition within BMSC seeded constructs was suppressed by the application of DC. Therefore, while the application of DC in vitro may only lead to modest improvements in the mechanical functionality of cartilaginous grafts, it may play an important role in the development of phenotypically stable constructs.

BMTC: --A Tool for Standardized Tissue Engineering on Ground and in Space ---

NASA Astrophysics Data System (ADS)

Kern, Peter; Kemmerle, Kurt; Jones, David

ESA is developing the BMTC (Biotechnology Mammalian Tissue Culture Facility) as ground demonstrator in order to: • establish a well characterised terrestrial platform for tissue engineer-ing under defined, reproducible conditions • prepare for future tissue engineering experiments in space using proven, well characterised, modular equipment. In the beginning the facility will be dedicated to support research of bone and cartilage growth under controlled mechanical and/or biochemical stimulation. Meanwhile, the industrial BMTC team has finalised the first model. The BMTC is highly automated system which provides standardized experiment hardware for tissue cultivation and stimulation under controlled conditions and the reproducible execution of the experiment according pre-programmed protocols. The BMTC consists of an incubator for the control of the experiment environment. Internally it offers all experiment relevant subsystems: • two Cultivation Units, each with eight Experiment Chamber Modules optical in-situ sensors for pO2 and pH • the Liquid Handling Device for medium exchange and sample taking • the handling devices for the internal transport of the experiment chamber modules to different experiment services • workstations for uni-axial loading of tissue samples; ZETOS (for bone tissue) / CHONDROS (for cartilage tissue) provision of reproducible displacement profiles measurement of the resulting forces computation of the visco-eleastic properties of the samples provision of flow induced shear stress fluorescence microscope • two different reactor types are included in the baseline flat reactor for 2D-and flat 3D-cultures with flow induced shear stress stimulation compatible with microscope cylindrical 3D-reactor for cultivation of vital bone and cartilage samples compatible with un-directional stimulation / analysis by ZETOS / CHONDROS. The modular, flexible design of the system allows the servicing and accommodation of a wide range of other experiment specific reactors. The functional principles and the essential features for controlled experiments will be reported. This facility complements the research done on ground on osteoporosis and the bone and muscle loss during bed rest studies during space flights. It is considered to become a new in-orbit research tool for tissue engineering and the verification of mechanical or pharmaceutical countermeasures.

Pullout of a Rigid Insert Adhesively Bonded to an Elastic Half Plane.

DTIC Science & Technology

1983-12-01

COMMAND UNITED STATES AIR FORCE C-= °84 02 13 071. C,, W % d 6 This document was prepared by the Department of Engineering Mechanics, USAF Academy Faculty...THOMAS E. KULLGREN, Lt Col, USAF Project Engineer /Scientist Professor and Acting Head, Department of Engineering Mechanics KENNETH E. SIEGETH Lt Col...Department of Engineering (Ifapphicable) Mechanics USAFA/DFEM 6c. ADDRESS (City. State and ZIP Code) 7b. ADDRESS (City, Slate and ZIP Code) USAF Academy

40 CFR 91.311 - Test conditions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... engine air at the inlet to the engine and the dry atmospheric pressure (designated as p s and expressed... rates at standard conditions for temperature and pressure. Use these conditions consistently throughout all calculations. Standard conditions for temperature and pressure are 25 °C and 101.3 kPa. (b) Engine...

40 CFR 90.311 - Test conditions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... pressure, and use these conditions consistently throughout all calculations. Standard conditions for temperature and pressure are 25 °C and 101.3 kPa. (b) Engine test conditions. Measure the absolute temperature (designated as T and expressed in Kelvin) of the engine air at the inlet to the engine and the dry atmospheric...

Engineering mechanical microenvironment of macrophage and its biomedical applications.

PubMed

Li, Jing; Li, Yuhui; Gao, Bin; Qin, Chuanguang; He, Yining; Xu, Feng; Yang, Hui; Lin, Min

2018-03-01

Macrophages are the most plastic cells in the hematopoietic system and can be widely found in almost all tissues. Recently studies have shown that mechanical cues (e.g., matrix stiffness and stress/strain) can significantly affect macrophage behaviors. Although existing reviews on the physical and mechanical cues that regulate the macrophage's phenotype are available, engineering mechanical microenvironment of macrophages in vitro as well as a comprehensive overview and prospects for their biomedical applications (e.g., tissue engineering and immunotherapy) has yet to be summarized. Thus, this review provides an overview on the existing methods for engineering mechanical microenvironment of macrophages in vitro and then a section on their biomedical applications and further perspectives are presented.

Power and energy ratios in mechanical CVT drive control

NASA Astrophysics Data System (ADS)

Balakin, P. D.; Stripling, L. O.

2017-06-01

Being based on the principle of providing the systems with adaptation property to the real parameters and operational condition, the mechanical system capable to control automatically the components of convertible power is offered and this allows providing stationary operation of the vehicle engine in the terms of variable external loading. This is achieved by drive control integrated in the power transmission, which implements an additional degree of freedom and operates on the basis of the laws of motion, with the energy of the main power flow by changing automatically the kinematic characteristics of the power transmission, this system being named CVT. The power and energy ratios found allow performing the necessary design calculations of the sections and the links of the mechanical CVT scheme.

Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems.

PubMed

Huh, Dongeun; Fujioka, Hideki; Tung, Yi-Chung; Futai, Nobuyuki; Paine, Robert; Grotberg, James B; Takayama, Shuichi

2007-11-27

We describe a microfabricated airway system integrated with computerized air-liquid two-phase microfluidics that enables on-chip engineering of human airway epithelia and precise reproduction of physiologic or pathologic liquid plug flows found in the respiratory system. Using this device, we demonstrate cellular-level lung injury under flow conditions that cause symptoms characteristic of a wide range of pulmonary diseases. Specifically, propagation and rupture of liquid plugs that simulate surfactant-deficient reopening of closed airways lead to significant injury of small airway epithelial cells by generating deleterious fluid mechanical stresses. We also show that the explosive pressure waves produced by plug rupture enable detection of the mechanical cellular injury as crackling sounds.

An Educational Program of Mechatronics for Multidisciplinary Knowledge Acquisition

NASA Astrophysics Data System (ADS)

Watanuki, Keiichi; Kojima, Kazuyuki

Recently, as the technologies surrounding mechanical engineering have improved remarkably, the expectations for students who graduate from departments of mechanical engineering have increased. For example, in order to develop a mechatronics system, a student needs to integrate a wide variety of technologies, such as mechanical engineering, electrical and electronics engineering, and information technology. Therefore, from the perspective of educators, the current education system, which stresses expertizing each technology, should be replaced by an education system that stresses integrating multidisciplinary knowledge. In this paper, a trial education program for students of the department of mechanical engineering in our university, in which students are required to integrate multidisciplinary knowledge in order to develop a biologically-based robot, is described. Finally, the efficacy of the program is analyzed.

Development of GUI Type On-Line Condition Monitoring Program for a Turboprop Engine Using Labview

NASA Astrophysics Data System (ADS)

Kong, Changduk; Kim, Keonwoo

2011-12-01

Recently, an aero gas turbine health monitoring system has been developed for precaution and maintenance action against faults or performance degradations of the advanced propulsion system which occurs in severe environments such as high altitude, foreign object damage particles, hot and heavy rain and snowy atmospheric conditions. However to establish this health monitoring system, the online condition monitoring program is firstly required, and the program must monitor the engine performance trend through comparison between measured engine performance data and base performance results calculated by base engine performance model. This work aims to develop a GUI type on-line condition monitoring program for the PT6A-67 turboprop engine of a high altitude and long endurance operation UAV using LabVIEW. The base engine performance of the on-line condition monitoring program is simulated using component maps inversely generated from the limited performance deck data provided by engine manufacturer. The base engine performance simulation program is evaluated because analysis results by this program agree well with the performance deck data. The proposed on-line condition program can monitor the real engine performance as well as the trend through precise comparison between clean engine performance results calculated by the base performance simulation program and measured engine performance signals. In the development phase of this monitoring system, a signal generation module is proposed to evaluate the proposed online monitoring system. For user friendly purpose, all monitoring program are coded by LabVIEW, and monitoring examples are demonstrated using the proposed GUI type on-condition monitoring program.

Engineering Graphene Mechanical Systems

DTIC Science & Technology

2012-07-05

strength material. On the basis of chemical /defect manipulation and recrystallization this technique allows wide-range engineering of mechanical... Engineering Graphene Mechanical Systems Maxim K. Zalalutdinov,† Jeremy T. Robinson,*,† Chad E. Junkermeier,‡ James C. Culbertson, Thomas L. Reinecke...Information ABSTRACT: We report a method to introduce direct bonding between graphene platelets that enables the transformation of a multilayer chemically

14 CFR 13.18 - Civil penalties: Administrative assessment against an individual acting as a pilot, flight...

Code of Federal Regulations, 2013 CFR

2013-01-01

... against an individual acting as a pilot, flight engineer, mechanic, or repairman. 13.18 Section 13.18... assessment against an individual acting as a pilot, flight engineer, mechanic, or repairman. (a) General. (1... procedures against an individual acting as a pilot, flight engineer, mechanic, or repairman, under 49 U.S.C...