An Overview of the MAGIC Project

DTIC Science & Technology

1993-12-01

unlimnitedj_ _______ 13. ABSTRACT (Mxmwn WO0 words) This note provides an overview of the MAGIC project1 which is developing a high-speed, wide-area...298Rv.9 16. PRICE COASSDE 3.1 17. SEURITY18. SEURITY19. SEURITY2930.2BIA NO An Overview of the M 93B0000173 MAGIC Project December 1993 Barbara B...Intelligence Division ii ABSTRACT This note provides an overview of the MAGIC project, which is developing a high-speed, wide- area networking testbed

Cooling interventions for athletes: An overview of effectiveness, physiological mechanisms, and practical considerations

PubMed Central

Bongers, Coen C. W. G.; Hopman, Maria T. E.; Eijsvogels, Thijs M. H.

2017-01-01

ABSTRACT Exercise-induced increases in core body temperature could negative impact performance and may lead to development of heat-related illnesses. The use of cooling techniques prior (pre-cooling), during (per-cooling) or directly after (post-cooling) exercise may limit the increase in core body temperature and therefore improve exercise performance. The aim of the present review is to provide a comprehensive overview of current scientific knowledge in the field of pre-cooling, per-cooling and post-cooling. Based on existing studies, we will discuss 1) the effectiveness of cooling interventions, 2) the underlying physiological mechanisms and 3) practical considerations regarding the use of different cooling techniques. Furthermore, we tried to identify the optimal cooling technique and compared whether cooling-induced performance benefits are different between cool, moderate and hot ambient conditions. This article provides researchers, physicians, athletes and coaches with important information regarding the implementation of cooling techniques to maintain exercise performance and to successfully compete in thermally stressful conditions. PMID:28349095

Mechanisms for cytoplasmic organization: an overview.

PubMed

Pagliaro, L

2000-01-01

One of the basic characteristics of life is the intrinsic organization of cytoplasm, yet we know surprisingly little about the manner in which cytoplasmic macromolecules are arranged. It is clear that cytoplasm is not the homogeneous "soup" it was once envisioned to be, but a comprehensive model for cytoplasmic organization is not available in modern cell biology. The premise of this volume is that phase separation in cytoplasm may play a role in organization at the subcellular level. Other mechanisms for non-membrane-bounded intracellular organization have previously been proposed. Some of these will be reviewed in this chapter. Multiple mechanisms, involving phase separation, specific intracellular targeting, formation of macromolecular complexes, and channeling, all could well contribute to cytoplasmic organization. Temporal and spatial organization, as well as composition, are likely to be important in defining the characteristics of cytoplasm.

DIOXINS: AN OVERVIEW

EPA Science Inventory

Introduction: Dioxins have been featured in the news recently following a poisoning incident in Europe.1-3 Because physicians are not usually taught much about the dioxins, this article attempts to provide an overview for practicing physicians. Dioxins are unwanted contaminants ...

An Overview of the Molecular Mechanisms of Recombinational DNA Repair

PubMed Central

Kowalczykowski, Stephen C.

2015-01-01

Recombinational DNA repair is a universal aspect of DNA metabolism and is essential for genomic integrity. It is a template-directed process that uses a second chromosomal copy (sister, daughter, or homolog) to ensure proper repair of broken chromosomes. The key steps of recombination are conserved from phage through human, and an overview of those steps is provided in this review. The first step is resection by helicases and nucleases to produce single-stranded DNA (ssDNA) that defines the homologous locus. The ssDNA is a scaffold for assembly of the RecA/RAD51 filament, which promotes the homology search. On finding homology, the nucleoprotein filament catalyzes exchange of DNA strands to form a joint molecule. Recombination is controlled by regulating the fate of both RecA/RAD51 filaments and DNA pairing intermediates. Finally, intermediates that mature into Holliday structures are disjoined by either nucleolytic resolution or topological dissolution. PMID:26525148

Autonomous Mechanical Assembly on the Space Shuttle: An Overview

NASA Technical Reports Server (NTRS)

Raibert, M. H.

1979-01-01

The space shuttle will be equipped with a pair of 50 ft. manipulators used to handle payloads and to perform mechanical assembly operations. Although current plans call for these manipulators to be operated by a human teleoperator. The possibility of using results from robotics and machine intelligence to automate this shuttle assembly system was investigated. The major components of an autonomous mechanical assembly system are examined, along with the technology base upon which they depend. The state of the art in advanced automation is also assessed.

Mountains: An Overview.

ERIC Educational Resources Information Center

Byers, Alton; Gilligan, Nancy; Golston, Syd; Linville, Rex

1999-01-01

Introduces the lessons from "Mountain: A Global Resource" that were developed by the National Council for the Social Studies (NCSS) and The Mountain Institute for use by NCSS members and their students. Provides an overview that introduces the mountains, mountain cultures, historical perceptions, and the geographical importance of…

Hypermedia Concepts and Research: An Overview.

ERIC Educational Resources Information Center

Burton, John K.; And Others

1995-01-01

Provides an overview of hypermedia, including a history of hypertext and multimedia, and discusses how they have been combined into the term hypermedia; a cognitive overview; dual coding and cue summation; and theories related to learners, including field dependence-independence, memory, and metacognition. Contains 156 references. (LRW)

Bubbles in an acoustic field: an overview.

PubMed

Ashokkumar, Muthupandian; Lee, Judy; Kentish, Sandra; Grieser, Franz

2007-04-01

Acoustic cavitation is the fundamental process responsible for the initiation of most of the sonochemical reactions in liquids. Acoustic cavitation originates from the interaction between sound waves and bubbles. In an acoustic field, bubbles can undergo growth by rectified diffusion, bubble-bubble coalescence, bubble dissolution or bubble collapse leading to the generation of primary radicals and other secondary chemical reactions. Surface active solutes have been used in association with a number of experimental techniques in order to isolate and understand these activities. A strobe technique has been used for monitoring the growth of a single bubble by rectified diffusion. Multibubble sonoluminescence has been used for monitoring the growth of the bubbles as well as coalescence between bubbles. The extent of bubble coalescence has also been monitored using a newly developed capillary technique. An overview of the various experimental results has been presented in order to highlight the complexities involved in acoustic cavitation processes, which on the other hand arise from a simple, mechanical interaction between sound waves and bubbles.

An introduction to the mechanics of DNA.

PubMed

Travers, A A; Thompson, J M T

2004-07-15

This article gives an overview of recent research on the mechanical properties and spatial deformations of the DNA molecule. Globally the molecule behaves like a uniform elastic rod, and its twisting and writhing govern its compaction and packaging within a cell. Meanwhile high mechanical stresses can induce structural transitions of DNA giving, for example, a phase diagram in the space of the applied tension and torque. Locally, the mechanical properties vary according to the local sequence organization. These variations play a vital role in the biological functioning of the molecule.

Study Canada: An Overview.

ERIC Educational Resources Information Center

Monahan, Robert L.; And Others

The document presents the first of five units on Canada developed for classroom use in American secondary schools. This unit, an overview of Canada, offers a sequence of information sheets for students and class activity suggestions for teachers which use a comparative approach stressing an understanding of Canada from the viewpoints of both…

An Overview of Audacity

ERIC Educational Resources Information Center

Thompson, Douglas Earl

2014-01-01

This article is an overview of the open source audio-editing and -recording program, Audacity. Key features are noted, along with significant features not included in the program. A number of music and music technology concepts are identified that could be taught and/or reinforced through using Audacity.

An overview of C. elegans biology.

PubMed

Strange, Kevin

2006-01-01

The establishment of Caenorhabditis elegans as a "model organism" began with the efforts of Sydney Brenner in the early 1960s. Brenner's focus was to find a suitable animal model in which the tools of genetic analysis could be used to define molecular mechanisms of development and nervous system function. C. elegans provides numerous experimental advantages for such studies. These advantages include a short life cycle, production of large numbers of offspring, easy and inexpensive laboratory culture, forward and reverse genetic tractability, and a relatively simple anatomy. This chapter will provide a brief overview of C. elegans biology.

Kinematic design considerations for minimally invasive surgical robots: an overview.

PubMed

Kuo, Chin-Hsing; Dai, Jian S; Dasgupta, Prokar

2012-06-01

Kinematic design is a predominant phase in the design of robotic manipulators for minimally invasive surgery (MIS). However, an extensive overview of the kinematic design issues for MIS robots is not yet available to both mechanisms and robotics communities. Hundreds of archival reports and articles on robotic systems for MIS are reviewed and studied. In particular, the kinematic design considerations and mechanism development described in the literature for existing robots are focused on. The general kinematic design goals, design requirements, and design preferences for MIS robots are defined. An MIS-specialized mechanism, namely the remote center-of-motion (RCM) mechanism, is revisited and studied. Accordingly, based on the RCM mechanism types, a classification for MIS robots is provided. A comparison between eight different RCM types is given. Finally, several open challenges for the kinematic design of MIS robotic manipulators are discussed. This work provides a detailed survey of the kinematic design of MIS robots, addresses the research opportunity in MIS robots for kinematicians, and clarifies the kinematic point of view to MIS robots as a reference for the medical community. Copyright © 2012 John Wiley & Sons, Ltd.

Skin cancer: an overview of epidemiology and risk factors.

PubMed

Gordon, Randy

2013-08-01

To provide a general overview of malignant melanoma and non-melanoma skin cancer, with an emphasis on epidemiology, clinical presentation, and the multiple and varied risk factors associated with skin cancer. Peer-reviewed journal articles, government health reports, book chapters, and Web-based resources. Skin cancer is the most common carcinoma, affecting millions worldwide. Incidence is increasing yearly, making it a pre-eminent public health threat. Myriad factors increase the risk of skin cancer and may serve as important prognostic indicators for the disease. To provide nurses with a clearer understanding of the causative mechanisms of skin cancer and an improved awareness of the risk factors associated with the disease. Copyright © 2013 Elsevier Inc. All rights reserved.

The School Office: An Overview.

ERIC Educational Resources Information Center

Hudson, Randy

2000-01-01

Presents an overview of the fundamental principles of school office design that remain constant despite changes in building technologies, and technological and spatial flexibility. Principles discussed include the school office and traffic patterns, security, and visitor reception requirements. (GR)

An Energy Overview of the Czech Republic

DOE Office of Scientific and Technical Information (OSTI.GOV)

anon.

2003-10-17

The DOE Office of Fossil Energy is maintaining a web site that is meant to provide useful business- and energy-related information about countries and regions of the world for exporters, project developers, and researchers. The site consists of more than 130 country pages (organized into seven different world regions), with each country page having its own set of links to information sources about that country. There are also more than 30 Country Energy Overviews at the web site -- each of these is a comprehensive review of a specific country's entire energy situation, including sections on Energy Policy, Oil, Naturalmore » Gas, Coal, Hydroelectric/Renewables, Nuclear Power, Energy Transmission Infrastructure, Electricity, Electric Industry Overview, Environmental Activities, Privatization, Trade, and Economic Situation. The specific country highlighted in this Country Energy Overview is the Czech Republic. The site is designed to be dynamic. Updates to the overviews will be made as need an d resources permit.« less

Biomimetics: lessons from nature--an overview.

PubMed

Bhushan, Bharat

2009-04-28

Nature has developed materials, objects and processes that function from the macroscale to the nanoscale. These have gone through evolution over 3.8 Gyr. The emerging field of biomimetics allows one to mimic biology or nature to develop nanomaterials, nanodevices and processes. Properties of biological materials and surfaces result from a complex interplay between surface morphology and physical and chemical properties. Hierarchical structures with dimensions of features ranging from the macroscale to the nanoscale are extremely common in nature to provide properties of interest. Molecular-scale devices, superhydrophobicity, self-cleaning, drag reduction in fluid flow, energy conversion and conservation, high adhesion, reversible adhesion, aerodynamic lift, materials and fibres with high mechanical strength, biological self-assembly, antireflection, structural coloration, thermal insulation, self-healing and sensory-aid mechanisms are some of the examples found in nature that are of commercial interest. This paper provides a broad overview of the various objects and processes of interest found in nature and applications under development or available in the marketplace.

An Overview of the State of the Art in Atomistic and Multiscale Simulation of Fracture

NASA Technical Reports Server (NTRS)

Saether, Erik; Yamakov, Vesselin; Phillips, Dawn R.; Glaessgen, Edward H.

2009-01-01

The emerging field of nanomechanics is providing a new focus in the study of the mechanics of materials, particularly in simulating fundamental atomic mechanisms involved in the initiation and evolution of damage. Simulating fundamental material processes using first principles in physics strongly motivates the formulation of computational multiscale methods to link macroscopic failure to the underlying atomic processes from which all material behavior originates. This report gives an overview of the state of the art in applying concurrent and sequential multiscale methods to analyze damage and failure mechanisms across length scales.

The Antiviral Activities and Mechanisms of Marine Polysaccharides: An Overview

PubMed Central

Wang, Wei; Wang, Shi-Xin; Guan, Hua-Shi

2012-01-01

Recently, the studies on the antiviral activities of marine natural products, especially marine polysaccharides, are attracting more and more attention all over the world. Marine-derived polysaccharides and their lower molecular weight oligosaccharide derivatives have been shown to possess a variety of antiviral activities. This paper will review the recent progress in research on the antiviral activities and the mechanisms of these polysaccharides obtained from marine organisms. In particular, it will provide an update on the antiviral actions of the sulfated polysaccharides derived from marine algae including carrageenans, alginates, and fucans, relating to their structure features and the structure–activity relationships. In addition, the recent findings on the different mechanisms of antiviral actions of marine polysaccharides and their potential for therapeutic application will also be summarized in detail. PMID:23235364

Timeline-Based Mission Operations Architecture: An Overview

NASA Technical Reports Server (NTRS)

Chung, Seung H.; Bindschadler, Duane L.

2012-01-01

Some of the challenges in developing a mission operations system and operating a mission can be traced back to the challenge of integrating a mission operations system from its many components and to the challenge of maintaining consistent and accountable information throughout the operations processes. An important contributing factor to both of these challenges is the file-centric nature of today's systems. In this paper, we provide an overview of these challenges and argue the need to move toward an information-centric mission operations system. We propose an information representation called Timeline as an approach to enable such a move, and we provide an overview of a Timeline-based Mission Operations System architecture.

An Overview of Human Figure Modeling for Army Aviation Systems

DTIC Science & Technology

2010-04-01

An Overview of Human Figure Modeling for Army Aviation Systems by Jamison S. Hicks, David B. Durbin, and Richard W. Kozycki ARL-TR-5154...April 2010 An Overview of Human Figure Modeling for Army Aviation Systems Jamison S. Hicks, David B. Durbin, and Richard W. Kozycki...TYPE Final 3. DATES COVERED (From - To) May 2009–August 2009 4. TITLE AND SUBTITLE An Overview of Human Figure Modeling for Army Aviation Systems

An Energy Overview of Romania

DOE Office of Scientific and Technical Information (OSTI.GOV)

anon.

2003-10-20

The DOE Office of Fossil Energy is maintaining a web site that is meant to provide useful business- and energy-related information about countries and regions of the world for exporters, project developers, and researchers. The site consists of more than 130 country pages (organized into seven different world regions), with each country page having its own set of links to information sources about that country. There are also more than 30 Country Energy Overviews at the web site -- each of these is a comprehensive review of a specific country's entire energy situation, including sections on Energy Policy, Oil, Naturalmore » Gas, Coal, Hydroelectric/Renewables, Nuclear Power, Energy Transmission Infrastructure, Electricity, Electric Industry Overview, Environmental Activities, Privatization, Trade, and Economic Situation. The specific country highlighted in this Country Energy Overview is Romania. The site is designed to be dynamic. Updates to the overviews will be made as need and resources permit.« less

An Energy Overview of Venezuela

DOE Office of Scientific and Technical Information (OSTI.GOV)

anon.

2003-10-20

The DOE Office of Fossil Energy is maintaining a web site that is meant to provide useful business- and energy-related information about countries and regions of the world for exporters, project developers, and researchers. The site consists of more than 130 country pages (organized into seven different world regions), with each country page having its own set of links to information sources about that country. There are also more than 30 Country Energy Overviews at the web site -- each of these is a comprehensive review of a specific country's entire energy situation, including sections on Energy Policy, Oil, Naturalmore » Gas, Coal, Hydroelectric/Renewables, Nuclear Power, Energy Transmission Infrastructure, Electricity, Electric Industry Overview, Environmental Activities, Privatization, Trade, and Economic Situation. The specific country highlighted in this Country Energy Overview is Venezuela. The site is designed to be dynamic. Updates to the overviews will be made as need and resources permit.« less

An Energy Overview of Argentina

DOE Office of Scientific and Technical Information (OSTI.GOV)

anon.

2003-10-20

The DOE Office of Fossil Energy is maintaining a web site that is meant to provide useful business- and energy-related information about countries and regions of the world for exporters, project developers, and researchers. The site consists of more than 130 country pages (organized into seven different world regions), with each country page having its own set of links to information sources about that country. There are also more than 30 Country Energy Overviews at the web site -- each of these is a comprehensive review of a specific country's entire energy situation, including sections on Energy Policy, Oil, Naturalmore » Gas, Coal, Hydroelectric/Renewables, Nuclear Power, Energy Transmission Infrastructure, Electricity, Electric Industry Overview, Environmental Activities, Privatization, Trade, and Economic Situation. The specific country highlighted in this Country Energy Overview is Argentina. The site is designed to be dynamic. Updates to the overviews will be made as need and resources permit.« less

An Overview of the Transactional Interpretation of Quantum Mechanics

NASA Astrophysics Data System (ADS)

Cramer, John G.

1988-02-01

The transactional interpretation of quantum mechanics (TI) is summarized and various points concerning the TI and its relation to the Copenhagen interpretation (CI) are considered. Questions concerning mapping the TI onto the CI, of advanced waves as solutions to proper wave equations, of collapse and the QM formalism, and of the relation of quantum mechanical interpretations to experimental tests and results are discussed.

An overview of the transactional interpretation of quantum mechanics

NASA Astrophysics Data System (ADS)

Cramer, J. G.

We summarize the transactional interpretation (TI) of quantum mechanics (QM) and consider various points concerning the TI and its relation to the Copenhagen interpretation (CI). Questions concerning mapping the TI onto the CI, of advanced waves as solutions to proper wave equations, of collapse and the QM formalism, and of the relation of quantum mechanical interpretations to experimental tests and results are discussed.

The Practice of Campus-Based Threat Assessment: An Overview

ERIC Educational Resources Information Center

Pollard, Jeffrey W.; Nolan, Jeffrey J.; Deisinger, Eugene R. D.

2012-01-01

This article provides an overview of threat assessment and management as implemented on campuses of higher education. Standards of practice and state calls for implementation are cited. An overview of some of the basic principles for threat assessment and management implementation is accompanied by examples of how they are utilized. Pitfalls…

An Overview of Video Description: History, Benefits, and Guidelines

ERIC Educational Resources Information Center

Packer, Jaclyn; Vizenor, Katie; Miele, Joshua A.

2015-01-01

This article provides an overview of the historical context in which video description services have evolved in the United States, a summary of research demonstrating benefits to people with vision loss, an overview of current video description guidelines, and information about current software programs that are available to produce video…

Mechanical Systems

NASA Technical Reports Server (NTRS)

Davis, Robert E.

2002-01-01

The presentation provides an overview of requirement and interpretation letters, mechanical systems safety interpretation letter, design and verification provisions, and mechanical systems verification plan.

Medical smart textiles based on fiber optic technology: an overview.

PubMed

Massaroni, Carlo; Saccomandi, Paola; Schena, Emiliano

2015-04-13

The growing interest in the development of smart textiles for medical applications is driven by the aim to increase the mobility of patients who need a continuous monitoring of such physiological parameters. At the same time, the use of fiber optic sensors (FOSs) is gaining large acceptance as an alternative to traditional electrical and mechanical sensors for the monitoring of thermal and mechanical parameters. The potential impact of FOSs is related to their good metrological properties, their small size and their flexibility, as well as to their immunity from electromagnetic field. Their main advantage is the possibility to use textile based on fiber optic in a magnetic resonance imaging environment, where standard electronic sensors cannot be employed. This last feature makes FOSs suitable for monitoring biological parameters (e.g., respiratory and heartbeat monitoring) during magnetic resonance procedures. Research interest in combining FOSs and textiles into a single structure to develop wearable sensors is rapidly growing. In this review we provide an overview of the state-of-the-art of textiles, which use FOSs for monitoring of mechanical parameters of physiological interest. In particular we briefly describe the working principle of FOSs employed in this field and their relevant advantages and disadvantages. Also reviewed are their applications for the monitoring of mechanical parameters of physiological interest.

Assessment and diffusion of medical innovations in France: an overview.

PubMed

Dubromel, Amélie; Geffroy, Loïc; Aulagner, Gilles; Dussart, Claude

2018-01-01

Background: In France, a significant part of health expenditure is publicly funding. This put a heavy burden on society. In an economic context requiring tight control of public spending, it seems relevant to control the diffusion of medical innovations. That is why health technology assessment is subject to an increasing interest at national level for management and approval decisions. This article provides an overview of the assessment and diffusion of medical innovation in France. Method: The data are extracted from French authorities or organisations websites and documents and from French legislative texts. In addition, regarding discussion, a search in MEDLINE database was carried out. Results: An overview of the assessment and diffusion of medical innovation in France is given by presenting the different types of medical innovations according to French health system definition (I); introducing French authorities participating to health technology assessment and describe assessment procedures of medical innovations (II); and giving details about market access process of innovative health product in France (III). Key opportunities and challenges of medical innovation assessment and diffusion in France are discussed at the end of this article. Conclusion: In France, medical innovation is considered as a crucial component for quality of care and performance of healthcare system. The aim of health technology assessment is to promote a secure and timely access to innovation for patients. Nevertheless, it appears necessary to improve regulatory mechanisms.

[The DSM-V : An overview].

PubMed

Loas, G

The aim of the present article is to present an overview of the recently published 5th version of the DSM. After a brief historic of the different versions of the DSM since the third edition, the main features of the classification were presented followed by the particularities of the fifth version.

Panic disorder and cardiovascular diseases: an overview.

PubMed

Machado, Sergio; Sancassiani, Federica; Paes, Flavia; Rocha, Nuno; Murillo-Rodriguez, Eric; Nardi, Antonio Egidio

2017-10-01

The association between panic disorder (PD) and cardiovascular diseases (CVD) has been extensively studied in recent years and, although some studies have shown anxiety disorders co-existing or increasing the risk of heart disease, no causal hypothesis has been well established. Thus, a critical review was performed of the studies that evaluated the association between PD and cardiovascular diseases; synthesizing the evidence on the mechanisms mediators that theoretically would be the responsible for the causal pathway between PD and CVD, specifically. This overview shows epidemiological studies, and discusses biological mechanisms that could link PD to CVD, such as pleiotropy, heart rate variability, unhealthy lifestyle, atherosclerosis, mental stress, and myocardial perfusion defects. This study tried to provide a comprehensive narrative synthesis of previously published information regarding PD and CVD and open new possibilities of clinical management and pathophysiological understanding. Some epidemiological studies have indicated that PD could be a risk factor for CVD, raising morbidity and mortality in PD, suggesting an association between them. These studies argue that PD pathophysiology could cause or potentiate CVD. However, there is no evidence in favour of a causal relationship between PD and CVD. Therefore, PD patients with suspicions of cardiovascular symptoms need redoubled attention.

Implementing an electronic medication overview in Belgium.

PubMed

Storms, Hannelore; Marquet, Kristel; Nelissen, Katherine; Hulshagen, Leen; Lenie, Jan; Remmen, Roy; Claes, Neree

2014-12-16

An accurate medication overview is essential to reduce medication errors. Therefore, it is essential to keep the medication overview up-to-date and to exchange healthcare information between healthcare professionals and patients. Digitally shared information yields possibilities to improve communication. However, implementing a digitally shared medication overview is challenging. This articles describes the development process of a secured, electronic platform designed for exchanging medication information as executed in a pilot study in Belgium, called "Vitalink". The goal of "Vitalink" is to improve the exchange of medication information between professionals working in healthcare and patients in order to achieve a more efficient cooperation and better quality of care. Healthcare professionals of primary and secondary health care and patients of four Belgian regions participated in the project. In each region project groups coordinated implementation and reported back to the steering committee supervising the pilot study. The electronic medication overview was developed based on consensus in the project groups. The steering committee agreed to establish secured and authorized access through the use of electronic identity documents (eID) and a secured, eHealth-platform conform prior governmental regulations regarding privacy and security of healthcare information. A successful implementation of an electronic medication overview strongly depends on the accessibility and usability of the tool for healthcare professionals. Coordinating teams of the project groups concluded, based on their own observations and on problems reported to them, that secured and quick access to medical data needed to be pursued. According to their observations, the identification process using the eHealth platform, crucial to ensure secured data, was very time consuming. Secondly, software packages should meet the needs of their users, thus be adapted to daily activities of healthcare

An overview of zinc addition for BWR dose rate control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marble, W.J.

1995-03-01

This paper presents an overview of the BWRs employing feedwater zinc addition to reduce primary system dose rates. It identifies which BWRs are using zinc addition and reviews the mechanical injection and passive addition hardware currently being employed. The impact that zinc has on plant chemistry, including the factor of two to four reduction in reactor water Co-60 concentrations, is discussed. Dose rate results, showing the benefits of implementing zinc on either fresh piping surfaces or on pipes with existing films are reviewed. The advantages of using zinc that is isotopically enhanced by the depletion of the Zn-64 precursor tomore » Zn-65 are identified.« less

An Overview. High Risk Series.

ERIC Educational Resources Information Center

General Accounting Office, Washington, DC.

This report provides an overview of efforts undertaken by the U.S. General Accounting Office (GAO) in 1990 to review and report on federal program areas its work identified as high risk because of vulnerabilities to waste, fraud, abuse, and mismanagement. It reviews the current status of efforts to address these concerns. The six categories of…

The NASA Geodynamics Program: An overview

NASA Technical Reports Server (NTRS)

1983-01-01

This NASA Geodynamics Program overview collectively examines the history, scientific basis, status, and results of the NASA Program and outlines plans for the next five to eight years. It is intended as an informative nontechnical discussion of geodynamics research.

Computational structural mechanics methods research using an evolving framework

NASA Technical Reports Server (NTRS)

Knight, N. F., Jr.; Lotts, C. G.; Gillian, R. E.

1990-01-01

Advanced structural analysis and computational methods that exploit high-performance computers are being developed in a computational structural mechanics research activity sponsored by the NASA Langley Research Center. These new methods are developed in an evolving framework and applied to representative complex structural analysis problems from the aerospace industry. An overview of the methods development environment is presented, and methods research areas are described. Selected application studies are also summarized.

An overview of the domestication and impact of the Salmonella mobilome.

PubMed

Mebrhatu, Mehari Tesfazgi; Cenens, William; Aertsen, Abram

2014-02-01

Salmonella spp. are accountable for a large fraction of the global infectious disease burden, with most of their infections being food- or water-borne. The phenotypic features and adaptive potential of Salmonella spp. appear to be driven to a large extent by mobile or laterally acquired genetic elements. A better understanding of the conduct and diversification of these important pathogens consequently requires a more profound insight into the different mechanisms by which these pivotal elements establish themselves in the cell and affect its behavior. This review, therefore, provides an overview of the physiological impact and domestication of the Salmonella mobilome.

An overview of computer vision

NASA Technical Reports Server (NTRS)

Gevarter, W. B.

1982-01-01

An overview of computer vision is provided. Image understanding and scene analysis are emphasized, and pertinent aspects of pattern recognition are treated. The basic approach to computer vision systems, the techniques utilized, applications, the current existing systems and state-of-the-art issues and research requirements, who is doing it and who is funding it, and future trends and expectations are reviewed.

Medical Smart Textiles Based on Fiber Optic Technology: An Overview

PubMed Central

Massaroni, Carlo; Saccomandi, Paola; Schena, Emiliano

2015-01-01

The growing interest in the development of smart textiles for medical applications is driven by the aim to increase the mobility of patients who need a continuous monitoring of such physiological parameters. At the same time, the use of fiber optic sensors (FOSs) is gaining large acceptance as an alternative to traditional electrical and mechanical sensors for the monitoring of thermal and mechanical parameters. The potential impact of FOSs is related to their good metrological properties, their small size and their flexibility, as well as to their immunity from electromagnetic field. Their main advantage is the possibility to use textile based on fiber optic in a magnetic resonance imaging environment, where standard electronic sensors cannot be employed. This last feature makes FOSs suitable for monitoring biological parameters (e.g., respiratory and heartbeat monitoring) during magnetic resonance procedures. Research interest in combining FOSs and textiles into a single structure to develop wearable sensors is rapidly growing. In this review we provide an overview of the state-of-the-art of textiles, which use FOSs for monitoring of mechanical parameters of physiological interest. In particular we briefly describe the working principle of FOSs employed in this field and their relevant advantages and disadvantages. Also reviewed are their applications for the monitoring of mechanical parameters of physiological interest. PMID:25871010

Assessment and diffusion of medical innovations in France: an overview

PubMed Central

Dubromel, Amélie; Geffroy, Loïc; Aulagner, Gilles; Dussart, Claude

2018-01-01

ABSTRACT Background: In France, a significant part of health expenditure is publicly funding. This put a heavy burden on society. In an economic context requiring tight control of public spending, it seems relevant to control the diffusion of medical innovations. That is why health technology assessment is subject to an increasing interest at national level for management and approval decisions. This article provides an overview of the assessment and diffusion of medical innovation in France. Method: The data are extracted from French authorities or organisations websites and documents and from French legislative texts. In addition, regarding discussion, a search in MEDLINE database was carried out. Results: An overview of the assessment and diffusion of medical innovation in France is given by presenting the different types of medical innovations according to French health system definition (I); introducing French authorities participating to health technology assessment and describe assessment procedures of medical innovations (II); and giving details about market access process of innovative health product in France (III). Key opportunities and challenges of medical innovation assessment and diffusion in France are discussed at the end of this article. Conclusion: In France, medical innovation is considered as a crucial component for quality of care and performance of healthcare system. The aim of health technology assessment is to promote a secure and timely access to innovation for patients. Nevertheless, it appears necessary to improve regulatory mechanisms. PMID:29686802

In silico gene expression analysis – an overview

PubMed Central

Murray, David; Doran, Peter; MacMathuna, Padraic; Moss, Alan C

2007-01-01

Efforts aimed at deciphering the molecular basis of complex disease are underpinned by the availability of high throughput strategies for the identification of biomolecules that drive the disease process. The completion of the human genome-sequencing project, coupled to major technological developments, has afforded investigators myriad opportunities for multidimensional analysis of biological systems. Nowhere has this research explosion been more evident than in the field of transcriptomics. Affordable access and availability to the technology that supports such investigations has led to a significant increase in the amount of data generated. As most biological distinctions are now observed at a genomic level, a large amount of expression information is now openly available via public databases. Furthermore, numerous computational based methods have been developed to harness the power of these data. In this review we provide a brief overview of in silico methodologies for the analysis of differential gene expression such as Serial Analysis of Gene Expression and Digital Differential Display. The performance of these strategies, at both an operational and result/output level is assessed and compared. The key considerations that must be made when completing an in silico expression analysis are also presented as a roadmap to facilitate biologists. Furthermore, to highlight the importance of these in silico methodologies in contemporary biomedical research, examples of current studies using these approaches are discussed. The overriding goal of this review is to present the scientific community with a critical overview of these strategies, so that they can be effectively added to the tool box of biomedical researchers focused on identifying the molecular mechanisms of disease. PMID:17683638

An Overview of NASA's Contributions to Energy Technology

NASA Technical Reports Server (NTRS)

Lyons, Valerie J.; Levine, Arlene S.

2009-01-01

The National Aeronautics and Space Administration (NASA) is well known for its many contributions to advancing technology for the aviation and space industries. It may be surprising to some that it has also made a major impact in advancing energy technologies. This paper presents a historic overview of some of the energy programs that NASA was involved in, as well as presenting some current energy-related work that is relevant to both aerospace and non-aerospace needs. In the past, NASA developed prototype electric cars, low-emission gas turbines, wind turbines, and solar-powered villages, to name a few of the major energy projects. The fundamental expertise in fluid mechanics, heat transfer, thermodynamics, mechanical and electrical engineering, and other related fields, found in NASA s workforce, can easily be applied to develop creative solutions to energy problems in space, aviation, or terrestrial systems.

Engineering and Ecological Aspects of Dam Removal-An Overview

DTIC Science & Technology

2006-09-01

indicated. Figure 3. Teton Dam failure, Idaho, 1976 BENEFITS AND COSTS OF DAMS Dams have provided and continue to provide a diverse...ERDC TN-EMRRP-SR-80 1 Engineering and Ecological Aspects of Dam Removal—An Overview September 2006 By Jock Conyngham1, J. Craig Fischenich1...High ______________________________________________________________________ OVERVIEW Decommissioning and removing dams has

Webinar November 18: An Overview of the Hydrogen Fueling Infrastructure

Science.gov Websites

Research and Station Technology (H2FIRST) Project | News | NREL Webinar November 18: An Overview of the Hydrogen Fueling Infrastructure Research and Station Technology (H2FIRST) Project Webinar ) Project November 12, 2014 The Energy Department will present a live webinar entitled "An Overview of

Radiation Diffusion:. AN Overview of Physical and Numerical Concepts

NASA Astrophysics Data System (ADS)

Graziani, Frank

2005-12-01

An overview of the physical and mathematical foundations of radiation transport is given. Emphasis is placed on how the diffusion approximation and its transport corrections arise. An overview of the numerical handling of radiation diffusion coupled to matter is also given. Discussions center on partial temperature and grey methods with comments concerning fully implicit methods. In addition finite difference, finite element and Pert representations of the div-grad operator is also discussed

An Overview of the Swinburne Online Astronomy Courses

NASA Astrophysics Data System (ADS)

Dempsey, F.

2013-06-01

(Abstract only) An overview of the online astronomy courses at Swinburne University of Technology is presented for the benefit of AAVSO members who might be interested in the courses or programs. The decision to take the online Master's degree in astronomy at Swinburne was a natural evolution from being interested in astronomy at an early age, being an amateur astronomer all my life, and being a variable star observer and member of the AAVSO for the past several decades. This presentation provides an overview of the program and examples of the course materials, assignments, and projects that may provide some idea of the commitment and expectations for AAVSO members considering the program.

Alzheimer’s and Dementia: An Overview | NIH MedlinePlus the Magazine

MedlinePlus

... contents Alzheimer’s and Dementia: An Overview Follow us Alzheimer’s and Dementia: An Overview What is Dementia? Dementia ... for basic activities and daily living. What is Alzheimer’s disease? Alzheimer’s disease is the most common cause ...

(18)F-labeled positron emission tomographic radiopharmaceuticals in oncology: an overview of radiochemistry and mechanisms of tumor localization.

PubMed

Vallabhajosula, Shankar

2007-11-01

Molecular imaging is the visualization, characterization, and measurement of biological processes at the molecular and cellular levels in a living system. At present, positron emission tomography/computed tomography (PET/CT) is one the most rapidly growing areas of medical imaging, with many applications in the clinical management of patients with cancer. Although [(18)F]fluorodeoxyglucose (FDG)-PET/CT imaging provides high specificity and sensitivity in several kinds of cancer and has many applications, it is important to recognize that FDG is not a "specific" radiotracer for imaging malignant disease. Highly "tumor-specific" and "tumor cell signal-specific" PET radiopharmaceuticals are essential to meet the growing demand of radioisotope-based molecular imaging technology. In the last 15 years, many alternative PET tracers have been proposed and evaluated in preclinical and clinical studies to characterize the tumor biology more appropriately. The potential clinical utility of several (18)F-labeled radiotracers (eg, fluoride, FDOPA, FLT, FMISO, FES, and FCH) is being reviewed by several investigators in this issue. An overview of design and development of (18)F-labeled PET radiopharmaceuticals, radiochemistry, and mechanism(s) of tumor cell uptake and localization of radiotracers are presented here. The approval of clinical indications for FDG-PET in the year 2000 by the Food and Drug Administration, based on a review of literature, was a major breakthrough to the rapid incorporation of PET into nuclear medicine practice, particularly in oncology. Approval of a radiopharmaceutical typically involves submission of a "New Drug Application" by a manufacturer or a company clearly documenting 2 major aspects of the drug: (1) manufacturing of PET drug using current good manufacturing practices and (2) the safety and effectiveness of a drug with specific indications. The potential routine clinical utility of (18)F-labeled PET radiopharmaceuticals depends also on

Research in Corporate Communication: An Overview of an Emerging Field.

ERIC Educational Resources Information Center

van Riel, Cees B. M.

1997-01-01

Provides an overview of research in corporate communication, focusing on achievements found in the international academic literature in both communication and business school disciplines. Gives three key concepts in such research: corporate identity, corporate reputation, and orchestration of communication. Advocates an interdisciplinary approach…

Red blood cell-derived microparticles: An overview.

PubMed

Westerman, Maxwell; Porter, John B

2016-07-01

The red blood cell (RBC) is historically the original parent cell of microparticles (MPs). In this overview, we describe the discovery and the early history of red cell-derived microparticles (RMPs) and present an overview of the evolution of RMP. We report the formation, characteristics, effects of RMP and factors which may affect RMP evaluation. The review examines RMP derived from both normal and pathologic RBC. The pathologic RBC studies include sickle cell anemia (SCA), sickle cell trait (STr), thalassemia intermedia (TI), hereditary spherocytosis (HS), hereditary elliptocytosis (HE), hereditary stomatocytosis (HSt) and glucose-6-phosphate dehydrogenase deficiency (G6PD). Copyright © 2016 Elsevier Inc. All rights reserved.

Assessment and Learning Technologies: An Overview

ERIC Educational Resources Information Center

Farrell, Treasa; Rushby, Nick

2016-01-01

Assessment pervades the learning process. This paper provides an overview of the application of technology to support and enhance diagnostic, formative and summative assessment. The focus is on examining how it can replace what already exists, improve the functionality, catalyse a redesign of the process and in some circumstances, make possible…

An Overview of Heart Rate Variability Metrics and Norms

PubMed Central

Shaffer, Fred; Ginsberg, J. P.

2017-01-01

Healthy biological systems exhibit complex patterns of variability that can be described by mathematical chaos. Heart rate variability (HRV) consists of changes in the time intervals between consecutive heartbeats called interbeat intervals (IBIs). A healthy heart is not a metronome. The oscillations of a healthy heart are complex and constantly changing, which allow the cardiovascular system to rapidly adjust to sudden physical and psychological challenges to homeostasis. This article briefly reviews current perspectives on the mechanisms that generate 24 h, short-term (~5 min), and ultra-short-term (<5 min) HRV, the importance of HRV, and its implications for health and performance. The authors provide an overview of widely-used HRV time-domain, frequency-domain, and non-linear metrics. Time-domain indices quantify the amount of HRV observed during monitoring periods that may range from ~2 min to 24 h. Frequency-domain values calculate the absolute or relative amount of signal energy within component bands. Non-linear measurements quantify the unpredictability and complexity of a series of IBIs. The authors survey published normative values for clinical, healthy, and optimal performance populations. They stress the importance of measurement context, including recording period length, subject age, and sex, on baseline HRV values. They caution that 24 h, short-term, and ultra-short-term normative values are not interchangeable. They encourage professionals to supplement published norms with findings from their own specialized populations. Finally, the authors provide an overview of HRV assessment strategies for clinical and optimal performance interventions. PMID:29034226

Complement Evasion Strategies of Viruses: An Overview

PubMed Central

Agrawal, Palak; Nawadkar, Renuka; Ojha, Hina; Kumar, Jitendra; Sahu, Arvind

2017-01-01

Being a major first line of immune defense, the complement system keeps a constant vigil against viruses. Its ability to recognize large panoply of viruses and virus-infected cells, and trigger the effector pathways, results in neutralization of viruses and killing of the infected cells. This selection pressure exerted by complement on viruses has made them evolve a multitude of countermeasures. These include targeting the recognition molecules for the avoidance of detection, targeting key enzymes and complexes of the complement pathways like C3 convertases and C5b-9 formation – either by encoding complement regulators or by recruiting membrane-bound and soluble host complement regulators, cleaving complement proteins by encoding protease, and inhibiting the synthesis of complement proteins. Additionally, viruses also exploit the complement system for their own benefit. For example, they use complement receptors as well as membrane regulators for cellular entry as well as their spread. Here, we provide an overview on the complement subversion mechanisms adopted by the members of various viral families including Poxviridae, Herpesviridae, Adenoviridae, Flaviviridae, Retroviridae, Picornaviridae, Astroviridae, Togaviridae, Orthomyxoviridae and Paramyxoviridae. PMID:28670306

An interim overview of LDEF materials findings

NASA Technical Reports Server (NTRS)

Stein, Brad A.

1992-01-01

The flight and retrieval of the National Aeronautics and Space Administration's Long Duration Exposure Facility (LDEF) provided an opportunity for the study of the low-Earth orbit (LEO) environment and long-duration space environmental effects (SEE) on materials that is unparalleled in the history of the U.S. Space Program. The remarkable flight attitude stability of LDEF enables specific analyses of various individual and combined effects of LEO environmental parameters on identical materials on the same space vehicle. This paper provides an overview of the interim LDEF materials findings of the Principal Investigators and the Materials Special Investigation Group. In general, the LDEF data is remarkably consistent; LDEF will provide a 'benchmark' for materials design data bases for satellites in low-Earth orbit. Some materials were identified to be encouragingly resistant to LEO SEE for 5.8 years; other 'space qualified' materials displayed significant environmental degradation. Molecular contamination was widespread; LDEF offers an unprecedented opportunity to provide a unified perspective of unmanned LEO spacecraft contamination mechanisms. New material development requirements for long-term LEO missions have been identified and current ground simulation testing methods/data for new, durable materials concepts can be validated with LDEF results. LDEF findings are already being integrated into the design of Space Station Freedom.

Gulfnet in Saudi Arabia: An Overview.

ERIC Educational Resources Information Center

Al-Khulaifi, M.

1995-01-01

Provides an overview of the Gulfnet Academic network, set in the context of development in Saudi Arabia and the establishment of King Abdulaziz City for Science and Technology (KACST). Goals and objectives of KACST are presented, Gulfnet members in the Gulf States are listed, and Gulfnet management, services, and facilities are discussed. (JKP)

Imaging Techniques in Endodontics: An Overview

PubMed Central

Deepak, B. S.; Subash, T. S.; Narmatha, V. J.; Anamika, T.; Snehil, T. K.; Nandini, D. B.

2012-01-01

This review provides an overview of the relevance of imaging techniques such as, computed tomography, cone beam computed tomography, and ultrasound, to endodontic practice. Many limitations of the conventional radiographic techniques have been overcome by the newer methods. Advantages and disadvantages of various imaging techniques in endodontic practice are also discussed. PMID:22530184

An Overview of the Parent Project.

ERIC Educational Resources Information Center

Wohlford, Paul

An overview is presented of the final report of the Parent Project, which sought to demonstrate whether participant group methods are suitable for helping low-income parents help themselves and their preschool children in Head Start. The nature, rationale, and interrelationships among the various components of the project are specified. The first…

Low Vision Driving with Bioptics: An Overview

ERIC Educational Resources Information Center

Huss, Chuck; Corn, Anne

2004-01-01

This article presents an overview of driving for adolescents and adults who meet their states' visual requirements for low vision driving using bioptic lenses. It also discusses the outcomes of two studies of bioptic driver education.

Expert Systems: An Overview for Teacher-Librarians.

ERIC Educational Resources Information Center

Orwig, Gary; Barron, Ann

1992-01-01

Provides an overview of expert systems for teacher librarians. Highlights include artificial intelligence and expert systems; the development of the MYCIN medical expert system; rule-based expert systems; the use of expert system shells to develop a specific system; and how to select an appropriate application for an expert system. (11 references)…

An overview of systematic review.

PubMed

Baker, Kathy A; Weeks, Susan Mace

2014-12-01

Systematic review is an invaluable tool for the practicing clinician. A well-designed systematic review represents the latest and most complete information available on a particular topic or intervention. This article highlights the key elements of systematic review, what it is and is not, and provides an overview of several reputable organizations supporting the methodological development and conduct of systematic review. Important aspects for evaluating the quality of a systematic review are also included. Copyright © 2014 American Society of PeriAnesthesia Nurses. Published by Elsevier Inc. All rights reserved.

Regional traffic signal operations programs : an overview

DOT National Transportation Integrated Search

2009-10-01

This report provides an overview of practices related to developing and sustaining a Regional Traffic Signal Operations Program. The purpose for a Regional Traffic Signal Operations Program is to provide regional partners a formal framework to collec...

Regional traffic signal operations programs : an overview.

DOT National Transportation Integrated Search

2009-10-01

This report provides an overview of practices related to developing and sustaining a Regional Traffic Signal Operations : Program. The purpose for a Regional Traffic Signal Operations Program is to provide regional partners a formal framework to : co...

Results of coronal hole research: An overview

NASA Technical Reports Server (NTRS)

Wilson, R. M.

1976-01-01

An overview of the last 10 years of coronal hole research, in particular since 1970, is presented. The findings of the early investigations and the more recent results obtained with Skylab/Apollo Telescope Mount instrumentation are discussed.

Polymer-Ceramic Composite Materials for Pyroelectric Infrared Detectors: An Overview

NASA Technical Reports Server (NTRS)

Aggarwal, M. D; Currie, J. R.; Penn, B. G.; Batra, A. K.; Lal, R. B.

2007-01-01

Ferroelectrics:Polymer composites can be considered an established substitute for conventional electroceramics and ferroelectric polymers. The composites have a unique blend of polymeric properties such as mechanical flexibility, high strength, formability, and low cost, with the high electro-active properties of ceramic materials. They have attracted considerable interest because of their potential use in pyroelectric infrared detecting devices and piezoelectric transducers. These flexible sensors and transducers may eventually be useful for their health monitoring applications for NASA crew launch vehicles and crew exploration vehicles being developed. In the light of many technologically important applications in this field, it is worthwhile to present an overview of the pyroelectric infrared detector theory, models to predict dielectric behavior and pyroelectric coefficient, and the concept of connectivity and fabrication techniques of biphasic composites. An elaborate review of Pyroelectric-Polymer composite materials investigated to date for their potential use in pyroelectric infrared detectors is presented.

Brain Research and Education: An Overview.

ERIC Educational Resources Information Center

Hill, Kenneth L.

An overview of some educational implications of brain related research indicates that new insights can be gained from brain research. Four areas of study appear to be promising. First, the study of the evolution of the brain involves theories derived mostly from sociobiology, which is the study of the social behavior of animals, including humans…

An Overview of Sixteen Trends...Their Profound Impact on Our Future

ERIC Educational Resources Information Center

Marx, Gary

2011-01-01

The "Overview" is a condensation of the full Sixteen Trends book. This abbreviated version provides an economical opportunity to order in bulk and distribute copies to an entire school staff, community groups, or other clients and constituents. The "Overview of Sixteen Trends" is an important tool for raising awareness about the need to scan the…

Overview of paint removal methods

NASA Astrophysics Data System (ADS)

Foster, Terry

1995-04-01

With the introduction of strict environmental regulations governing the use and disposal of methylene chloride and phenols, major components of chemical paint strippers, there have been many new environmentally safe and effective methods of paint removal developed. The new methods developed for removing coatings from aircraft and aircraft components include: mechanical methods using abrasive media such as plastic, wheat starch, walnut shells, ice and dry ice, environmentally safe chemical strippers and paint softeners, and optical methods such as lasers and flash lamps. Each method has its advantages and disadvantages, and some have unique applications. For example, mechanical and abrasive methods can damage sensitive surfaces such as composite materials and strict control of blast parameters and conditions are required. Optical methods can be slow, leaving paint residues, and chemical methods may not remove all of the coating or require special coating formulations to be effective. As an introduction to environmentally safe and effective methods of paint removal, this paper is an overview of the various methods available. The purpose of this overview is to introduce the various paint removal methods available.

Creating Smart-er Cities: An Overview

ERIC Educational Resources Information Center

Allwinkle, Sam; Cruickshank, Peter

2011-01-01

The following offers an overview of what it means for cities to be "smart." It draws the supporting definitions and critical insights into smart cities from a series of papers presented at the 2009 Trans-national Conference on Creating Smart(er) Cities. What the papers all have in common is their desire to overcome the all too often…

Overview of NASA Cryocooler Programs

NASA Technical Reports Server (NTRS)

Boyle, R. F.; Ross, R. G., Jr.; Krebs, Carolyn A. (Technical Monitor)

2001-01-01

Mechanical cryocoolers represent a significant enabling technology for NASA's Earth and Space Science Enterprises, as well as augmenting existing capabilities in space exploration. An over-view is presented of on-going efforts at the Goddard Space Flight Center and the Jet Propulsion Laboratory in support of current flight projects, near-term flight instruments, and long-term technology development.

An overview of artificial intelligence and robotics. Volume 1: Artificial intelligence. Part C: Basic AI topics

NASA Technical Reports Server (NTRS)

Gevarter, W. B.

1983-01-01

Readily understandable overviews of search oriented problem solving, knowledge representation, and computational logic are provided. Mechanization, automation and artificial intelligence are discussed as well as how they interrelate.

Aviation combustion toxicology: an overview.

PubMed

Chaturvedi, Arvind K

2010-01-01

Aviation combustion toxicology is a subspecialty of the field of aerospace toxicology, which is composed of aerospace and toxicology. The term aerospace, that is, the environment extending above and beyond the surface of the Earth, is also used to represent the combined fields of aeronautics and astronautics. Aviation is another term interchangeably used with aerospace and aeronautics and is explained as the science and art of operating powered aircraft. Toxicology deals with the adverse effects of substances on living organisms. Although toxicology borrows knowledge from biology, chemistry, immunology, pathology, physiology, and public health, the most closely related field to toxicology is pharmacology. Economic toxicology, environmental toxicology, and forensic toxicology, including combustion toxicology, are the three main branches of toxicology. In this overview, a literature search for the period of 1960-2007 was performed and information related to aviation combustion toxicology collected. The overview included introduction; combustion, fire, and smoke; smoke gas toxicity; aircraft material testing; fire gases and their interactive effects; result interpretation; carboxyhemoglobin and blood cyanide ion levels; pyrolytic products of aircraft engine oils, fluids, and lubricants; and references. This review is anticipated to be an informative resource for aviation combustion toxicology and fire-related casualties.

Plasmonic Solar Cells: From Rational Design to Mechanism Overview.

PubMed

Jang, Yoon Hee; Jang, Yu Jin; Kim, Seokhyoung; Quan, Li Na; Chung, Kyungwha; Kim, Dong Ha

2016-12-28

Plasmonic effects have been proposed as a solution to overcome the limited light absorption in thin-film photovoltaic devices, and various types of plasmonic solar cells have been developed. This review provides a comprehensive overview of the state-of-the-art progress on the design and fabrication of plasmonic solar cells and their enhancement mechanism. The working principle is first addressed in terms of the combined effects of plasmon decay, scattering, near-field enhancement, and plasmonic energy transfer, including direct hot electron transfer and resonant energy transfer. Then, we summarize recent developments for various types of plasmonic solar cells based on silicon, dye-sensitized, organic photovoltaic, and other types of solar cells, including quantum dot and perovskite variants. We also address several issues regarding the limitations of plasmonic nanostructures, including their electrical, chemical, and physical stability, charge recombination, narrowband absorption, and high cost. Next, we propose a few potentially useful approaches that can improve the performance of plasmonic cells, such as the inclusion of graphene plasmonics, plasmon-upconversion coupling, and coupling between fluorescence resonance energy transfer and plasmon resonance energy transfer. This review is concluded with remarks on future prospects for plasmonic solar cell use.

Virtual Reality: An Overview.

ERIC Educational Resources Information Center

Franchi, Jorge

1994-01-01

Highlights of this overview of virtual reality include optics; interface devices; virtual worlds; potential applications, including medicine and archaeology; problems, including costs; current research and development; future possibilities; and a listing of vendors and suppliers of virtual reality products. (Contains 11 references.) (LRW)

Information Resources Management: An Overview for Educators.

ERIC Educational Resources Information Center

Daniel, Evelyn H.

This paper presents an overview of the emerging information resources management (IRM) concept and suggests reasons why IRM would be a useful framework for educational institutions. An introductory look at current information problems precedes a review of definitions of information and IRM in the literature, and a definition of IRM as used in this…

The Manhattan Project: An Overview

NASA Astrophysics Data System (ADS)

Reed, Cameron

2017-01-01

August 2017 will mark the 75th anniversary of the establishment of the United States Army's Manhattan Engineer District, which oversaw the development and deployment of the first generation of nuclear weapons during World War II. In this talk I give an overview of the Manhattan Project, touching on its historical context, genesis, organization, facilities, accomplishments, challenges encountered, and legacies. I will also comment briefly on some of its lesser-known aspects and the persistent popular mythologies that still surround it.

Neonatal Seizures: An Update on Mechanisms and Management

PubMed Central

Jensen, Frances E.

2010-01-01

The lifespan risk of seizures is highest in the neonatal period. Currently used therapies have limited efficacy. Although the treatment of neonatal seizures has not significantly changed in the last several decades, there has been substantial progress in understanding developmental mechanisms that influence seizure generation and responsiveness to anticonvulsants. Here we provide an overview of current approaches to the diagnosis and treatment of neonatal seizures, identifying some of the recent insights about the pathophysiology of neonatal seizures that may provide the foundation for better treatment. PMID:19944840

Observing System Simulation Experiments: An Overview

NASA Technical Reports Server (NTRS)

Prive, Nikki C.; Errico, Ronald M.

2016-01-01

An overview of Observing System Simulation Experiments (OSSEs) will be given, with focus on calibration and validation of OSSE frameworks. Pitfalls and practice will be discussed, including observation error characteristics, incestuousness, and experimental design. The potential use of OSSEs for investigation of the behaviour of data assimilation systems will be explored, including some results from experiments using the NASAGMAO OSSE.

An Overview of Recent Patents on Musculoskeletal Interface Tissue Engineering

PubMed Central

Rao, Rohit T.; Browe, Daniel P.; Lowe, Christopher J.; Freeman, Joseph W.

2018-01-01

Interface tissue engineering involves the development of engineered grafts that promote integration between multiple tissue types. Musculoskeletal tissue interfaces are critical to the safe and efficient transmission of mechanical forces between multiple musculoskeletal tissues e.g. between ligament and bone tissue. However, these interfaces often do not physiologically regenerate upon injury, resulting in impaired tissue function. Therefore, interface tissue engineering approaches are considered to be particularly relevant for the structural restoration of musculoskeletal tissues interfaces. In this article we provide an overview of the various strategies used for engineering musculoskeletal tissue interfaces with a specific focus on the recent important patents that have been issued for inventions that were specifically designed for engineering musculoskeletal interfaces as well as those that show promise to be adapted for this purpose. PMID:26577344

Pharmacotherapeutic Treatment of Alcohol Dependence: An Overview

ERIC Educational Resources Information Center

Graves, Erin; Goodwin, Lloyd R., Jr.

2008-01-01

Pharmacotherapy medications can reduce the likelihood of relapse, decrease craving intensity and severity of withdrawal symptoms, and bolster the likelihood of achieving and maintaining recovery goals for many individuals seeking recovery from alcohol dependence. An overview of the benefits and concerns of integrating pharmacotherapeutic…

Dictionaries of African Sign Languages: An Overview

ERIC Educational Resources Information Center

Schmaling, Constanze H.

2012-01-01

This article gives an overview of dictionaries of African sign languages that have been published to date most of which have not been widely distributed. After an introduction into the field of sign language lexicography and a discussion of some of the obstacles that authors of sign language dictionaries face in general, I will show problems…

Postconditioning hormesis put in perspective: an overview of experimental and clinical studies.

PubMed

Wiegant, F A C; Prins, H A B; Van Wijk, R

2011-01-01

A beneficial effect of applying mild stress to cells or organisms, that were initially exposed to a high dose of stress, has been referred to as 'postconditioning hormesis'. The initial high dose of stress activates intrinsic self-recovery mechanisms. Modulation of these endogenous adaptation strategies by administration of a subsequent low dose of stress can confer effects that are beneficial to the biological system. Owing to its potentially therapeutic applications, postconditioning hormesis is subject to research in various scientific disciplines. This paper presents an overview of the dynamics of postconditioning hormesis and illustrates this phenomenon with a number of examples in experimental and clinical research.

An Overview of the Human Systems Integration Division

NASA Technical Reports Server (NTRS)

Gore, Brian F.

2015-01-01

This presentation will provide an overview of the Human Systems Integration Division, and will highlight some of the human performance modeling efforts undertaken in previously presented MIDAS human performance modeling efforts.

Lewis materials research and technology: An overview

NASA Technical Reports Server (NTRS)

Grisaffe, Salvatore J.

1987-01-01

The Materials Division at the Lewis Research Center has a long record of contributions to both materials and process technology as well as to the understanding of key high-temperature phenomena. An overview of the division staff, facilities, past history, recent progress, and future interests is presented.

NEMS - National Energy Modeling System: An Overview

EIA Publications

2009-01-01

The National Energy Modeling System: An Overview 2009 a summary description of NEMS and each of its components. NEMS is a computer-based, energy-economy modeling system of energy markets for the midterm period through 2030. The NEMS is used to produce the Annual Energy Outlook.

Auriculotherapy in Neurology as an Evidence-Based Medicine: A Brief Overview.

PubMed

Stanton, Gary

2018-06-01

This article provides a brief overview of the use of auriculotherapy in the treatment of various neurologic conditions. This overview is not comprehensive and is meant to be primarily informative. It is based on the premise that auricular acupuncture is an evidence-based medicine.

An historical overview of cavity-enhanced methods

NASA Astrophysics Data System (ADS)

Paldus, B. A.; Kachanov, A. A.

2005-10-01

An historical overview of laser-based, spectroscopic methods that employ high-finesse optical resonators is presented. The overview begins with the early work in atomic absorption (1962) and optical cavities (1974) that led to the first mirror reflectivity measurements in 1980. This paper concludes with very recent extensions of cavity-enhanced methods for the study of condensed-phase media and biological systems. Methods described here include cavity ring-down spectroscopy, integrated cavity output spectroscopy, and noise-immune cavity-enhanced optical heterodyne molecular spectroscopy. Given the explosive growth of the field over the past decade, this review does not attempt to present a comprehensive bibliography of all work published in cavity-enhanced spectroscopy, but rather strives to illustrate the rich history, creative diversity, and broad applications potential of these methods.

Placental transfer and metabolism: an overview of the experimental models utilizing human placental tissue.

PubMed

Myllynen, Päivi; Vähäkangas, Kirsi

2013-02-01

Over the decades several ex vivo and in vitro models which utilize delivered human placenta have been developed to study various placental functions. The use of models originating from human placenta to study transplacental transfer and related mechanisms is an attractive option because human placenta is relatively easily available for experimental studies. After delivery placenta has served its purpose and is usually disposed of. The purpose of this review is to give an overview of the use of human placental models for the studies on human placental transfer and related mechanisms such as transporter functions and xenobiotic metabolism. Human placental perfusion, the most commonly used continuous cell lines, primary cells and tissue culture, as well as subcellular fractions are briefly introduced and their major advantages and disadvantages are discussed. Copyright © 2012 Elsevier Ltd. All rights reserved.

Auditory Processing Disorders: An Overview. ERIC Digest.

ERIC Educational Resources Information Center

Ciocci, Sandra R.

This digest presents an overview of children with auditory processing disorders (APDs), children who can typically hear information but have difficulty attending to, storing, locating, retrieving, and/or clarifying that information to make it useful for academic and social purposes. The digest begins by describing central auditory processing and…

Hard copies for digital medical images: an overview

NASA Astrophysics Data System (ADS)

Blume, Hartwig R.; Muka, Edward

1995-04-01

This paper is a condensed version of an invited overview on the technology of film hard-copies used in radiology. Because the overview was given to an essentially nonmedical audience, the reliance on film hard-copies in radiology is outlined in greater detail. The overview is concerned with laser image recorders generating monochrome prints on silver-halide films. The basic components of laser image recorders are sketched. The paper concentrates on the physical parameters - characteristic function, dynamic range, digitization resolution, modulation transfer function, and noise power spectrum - which define image quality and information transfer capability of the printed image. A preliminary approach is presented to compare the printed image quality with noise in the acquired image as well as with the noise of state-of- the-art cathode-ray-tube display systems. High-performance laser-image- recorder/silver-halide-film/light-box systems are well capable of reproducing acquired radiologic information. Most recently development was begun toward a display function standard for soft-copy display systems to facilitate similarity of image presentation between different soft-copy displays as well as between soft- and hard-copy displays. The standard display function is based on perceptional linearization. The standard is briefly reviewed to encourage the printer industry to adopt it, too.

Vibration suppression of advanced space cryocoolers - an overview

NASA Technical Reports Server (NTRS)

Ross, R. G., Jr.

2003-01-01

This paper provides an overview of the vibration characteristics of typical linear-drive space cryocoolers, outlines the history of development and typical performance of the various active and passive vibration suppression systems being used.

Microbial Degradation of Petroleum Hydrocarbon Contaminants: An Overview

PubMed Central

Das, Nilanjana; Chandran, Preethy

2011-01-01

One of the major environmental problems today is hydrocarbon contamination resulting from the activities related to the petrochemical industry. Accidental releases of petroleum products are of particular concern in the environment. Hydrocarbon components have been known to belong to the family of carcinogens and neurotoxic organic pollutants. Currently accepted disposal methods of incineration or burial insecure landfills can become prohibitively expensive when amounts of contaminants are large. Mechanical and chemical methods generally used to remove hydrocarbons from contaminated sites have limited effectiveness and can be expensive. Bioremediation is the promising technology for the treatment of these contaminated sites since it is cost-effective and will lead to complete mineralization. Bioremediation functions basically on biodegradation, which may refer to complete mineralization of organic contaminants into carbon dioxide, water, inorganic compounds, and cell protein or transformation of complex organic contaminants to other simpler organic compounds by biological agents like microorganisms. Many indigenous microorganisms in water and soil are capable of degrading hydrocarbon contaminants. This paper presents an updated overview of petroleum hydrocarbon degradation by microorganisms under different ecosystems. PMID:21350672

Neural correlates of math anxiety - an overview and implications.

PubMed

Artemenko, Christina; Daroczy, Gabriella; Nuerk, Hans-Christoph

2015-01-01

Math anxiety is a common phenomenon which can have a negative impact on numerical and arithmetic performance. However, so far little is known about the underlying neurocognitive mechanisms. This mini review provides an overview of studies investigating the neural correlates of math anxiety which provide several hints regarding its influence on math performance: while behavioral studies mostly observe an influence of math anxiety on difficult math tasks, neurophysiological studies show that processing efficiency is already affected in basic number processing. Overall, the neurocognitive literature suggests that (i) math anxiety elicits emotion- and pain-related activation during and before math activities, (ii) that the negative emotional response to math anxiety impairs processing efficiency, and (iii) that math deficits triggered by math anxiety may be compensated for by modulating the cognitive control or emotional regulation network. However, activation differs strongly between studies, depending on tasks, paradigms, and samples. We conclude that neural correlates can help to understand and explore the processes underlying math anxiety, but the data are not very consistent yet.

Lead poisoning: An overview

NASA Technical Reports Server (NTRS)

Gendel, Neil

1993-01-01

A problem that should be of great concern to all of us is the lead poisoning of children. First, I would like to present a short overview concerning the reasons everyone should care about lead poisoning, then discuss the history of lead poisoning, what is happening today across the country, and the future.

Jobs and the environment: An overview

NASA Astrophysics Data System (ADS)

Goodstein, Eban

1996-05-01

This paper provides an overview of economic research on the relationship between environmental protection and employment. The paper addresses, first, the impact of existing regulation on overall employment rates, shutdowns and layoffs, and regulation-induced capital flight from developed countries. Second, the paper provides a framework for evaluating claims that, over the longer run, environmental protection measures will boost overall employment and provide the foundation for a robust, sustainable economy.

High-performance computing — an overview

NASA Astrophysics Data System (ADS)

Marksteiner, Peter

1996-08-01

An overview of high-performance computing (HPC) is given. Different types of computer architectures used in HPC are discussed: vector supercomputers, high-performance RISC processors, various parallel computers like symmetric multiprocessors, workstation clusters, massively parallel processors. Software tools and programming techniques used in HPC are reviewed: vectorizing compilers, optimization and vector tuning, optimization for RISC processors; parallel programming techniques like shared-memory parallelism, message passing and data parallelism; and numerical libraries.

Role of AMPK in Diabetic Cardiovascular Complications: An Overview.

PubMed

Kumar, Ashutosh; Nellaiappan, Karthika; Yerra, Veera Ganesh

2018-05-07

Macrovascular complications of diabetes like cardiovascular diseases appear to be one of the leading causes of mortality. Current therapies aimed at counteracting the adverse effects of diabetes on cardiovascular system are found to be inadequate. Hence, there is growing need in search of novel targets. Adenosine monophosphate activated protein kinase (AMPK) is one such promising target, as a plethora of evidences point to its cardioprotective role in pathological milieu like cardiac hypertrophy, atherosclerosis and heart failure. AMPK is a serine-threonine kinase, which gets activated in response to a cellular depriving energy status. It orchestrates cellular metabolic response to energy demand and is, therefore, often referred to as "metabolic master switch" of the cell. In this review, we provide an overview of patho-mechanisms of diabetic cardiovascular disease; highlighting the role of AMPK in the regulation of this condition, followed by a description of extrinsic modulators of AMPK as potential therapeutic tools. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

An Overview.

PubMed

Nicolaidis, Efthymios; Delli, Eudoxie; Livanos, Nikolaos; Tampakis, Kostas; Vlahakis, George

2016-09-01

This essay offers an overview of the history of the relations between science and Eastern Christianity based on Greek-language sources. The civilizations concerned are the Byzantine Empire, the Christian Orthodox communities of the Ottoman Empire, and modern Greece, as a case study of a national state. Beginning with the Greek Church Fathers, the essay investigates the ideas of theologians and scholars on nature. Neoplatonism, the theological debates of Iconoclasm and Hesychasm, the proposed union of the Eastern and Western Churches, and the complex relations with the Hellenic past all had notable impacts on the conception of science held by the Byzantine Orthodox. From the sixteenth through the eighteenth centuries, the Christian Orthodox world did not actively participate in the making of the new science that was developing in modern Europe. It had to deal with the assimilation of scientific ideas produced by Western Christianity, and its main concern was the “legitimacy” of knowledge that did not originate directly from its own spiritual tradition. Finally, with regard to the Greek state, beyond the specific points of contact between the sciences and Orthodox Christianity—pertaining, for example, to materialism, evolution, and the calendar—the essay presents the constant background engagement with religion visible in most public pronouncements of scientists and intellectuals.

Youth Suicidal Behavior: An Introduction and Overview

ERIC Educational Resources Information Center

Miller, David N.; Eckert, Tanya L.

2009-01-01

Youth suicidal behavior continues to be a significant national problem in need of urgent attention by school personnel. The purpose of this introductory article to the special series is to provide an overview of youth suicidal behavior, including research-based information on demographic data; risk factors and warning signs; and where, when, and…

Overview of Lightweight Structures for Rotorcraft Engines and Drivetrains

NASA Technical Reports Server (NTRS)

Roberts, Gary D.

2011-01-01

This is an overview presentation of research being performed in the Advanced Materials Task within the NASA Subsonic Rotary Wing Project. This research is focused on technology areas that address both national goals and project goals for advanced rotorcraft. Specific technology areas discussed are: (1) high temperature materials for advanced turbines in turboshaft engines; (2) polymer matrix composites for lightweight drive system components; (3) lightweight structure approaches for noise and vibration control; and (4) an advanced metal alloy for lighter weight bearings and more reliable mechanical components. An overview of the technology in each area is discussed, and recent accomplishments are presented.

CARMENES: an overview six months after first light

NASA Astrophysics Data System (ADS)

Quirrenbach, A.; Amado, P. J.; Caballero, J. A.; Mundt, R.; Reiners, A.; Ribas, I.; Seifert, W.; Abril, M.; Aceituno, J.; Alonso-Floriano, F. J.; Anwand-Heerwart, H.; Azzaro, M.; Bauer, F.; Barrado, D.; Becerril, S.; Bejar, V. J. S.; Benitez, D.; Berdinas, Z. M.; Brinkmöller, M.; Cardenas, M. C.; Casal, E.; Claret, A.; Colomé, J.; Cortes-Contreras, M.; Czesla, S.; Doellinger, M.; Dreizler, S.; Feiz, C.; Fernandez, M.; Ferro, I. M.; Fuhrmeister, B.; Galadi, D.; Gallardo, I.; Gálvez-Ortiz, M. C.; Garcia-Piquer, A.; Garrido, R.; Gesa, L.; Gómez Galera, V.; González Hernández, J. I.; Gonzalez Peinado, R.; Grözinger, U.; Guàrdia, J.; Guenther, E. W.; de Guindos, E.; Hagen, H.-J.; Hatzes, A. P.; Hauschildt, P. H.; Helmling, J.; Henning, T.; Hermann, D.; Hernández Arabi, R.; Hernández Castaño, L.; Hernández Hernando, F.; Herrero, E.; Huber, A.; Huber, K. F.; Huke, P.; Jeffers, S. V.; de Juan, E.; Kaminski, A.; Kehr, M.; Kim, M.; Klein, R.; Klüter, J.; Kürster, M.; Lafarga, M.; Lara, L. M.; Lamert, A.; Laun, W.; Launhardt, R.; Lemke, U.; Lenzen, R.; Llamas, M.; Lopez del Fresno, M.; López-Puertas, M.; López-Santiago, J.; Lopez Salas, J. F.; Magan Madinabeitia, H.; Mall, U.; Mandel, H.; Mancini, L.; Marin Molina, J. A.; Maroto Fernández, D.; Martín, E. L.; Martín-Ruiz, S.; Marvin, C.; Mathar, R. J.; Mirabet, E.; Montes, D.; Morales, J. C.; Morales Muñoz, R.; Nagel, E.; Naranjo, V.; Nowak, G.; Palle, E.; Panduro, J.; Passegger, V. M.; Pavlov, A.; Pedraz, S.; Perez, E.; Pérez-Medialdea, D.; Perger, M.; Pluto, M.; Ramón, A.; Rebolo, R.; Redondo, P.; Reffert, S.; Reinhart, S.; Rhode, P.; Rix, H.-W.; Rodler, F.; Rodríguez, E.; Rodríguez López, C.; Rohloff, R. R.; Rosich, A.; Sanchez Carrasco, M. A.; Sanz-Forcada, J.; Sarkis, P.; Sarmiento, L. F.; Schäfer, S.; Schiller, J.; Schmidt, C.; Schmitt, J. H. M. M.; Schöfer, P.; Schweitzer, A.; Shulyak, D.; Solano, E.; Stahl, O.; Storz, C.; Tabernero, H. M.; Tala, M.; Tal-Or, L.; Ulbrich, R.-G.; Veredas, G.; Vico Linares, J. I.; Vilardell, F.; Wagner, K.; Winkler, J.; Zapatero Osorio, M.-R.; Zechmeister, M.; Ammler-von Eiff, M.; Anglada-Escudé, G.; del Burgo, C.; Garcia-Vargas, M. L.; Klutsch, A.; Lizon, J.-L.; Lopez-Morales, M.; Ofir, A.; Pérez-Calpena, A.; Perryman, M. A. C.; Sánchez-Blanco, E.; Strachan, J. B. P.; Stürmer, J.; Suárez, J. C.; Trifonov, T.; Tulloch, S. M.; Xu, W.

2016-08-01

The CARMENES instrument is a pair of high-resolution (R> 80,000) spectrographs covering the wavelength range from 0.52 to 1.71 μm, optimized for precise radial velocity measurements. It was installed and commissioned at the 3.5m telescope of the Calar Alto observatory in Southern Spain in 2015. The first large science program of CARMENES is a survey of 300 M dwarfs, which started on Jan 1, 2016. We present an overview of all subsystems of CARMENES (front end, fiber system, visible-light spectrograph, near-infrared spectrograph, calibration units, etalons, facility control, interlock system, instrument control system, data reduction pipeline, data flow, and archive), and give an overview of the assembly, integration, verification, and commissioning phases of the project. We show initial results and discuss further plans for the scientific use of CARMENES.

Early Childhood Music Education Research: An Overview

ERIC Educational Resources Information Center

Young, Susan

2016-01-01

This article offers a short commentary on the "state of play" in early childhood music education research to accompany the articles published in this special issue. It provides an international overview of recent research trends in this field, with examples drawn from Europe, the Americas, Asia, the Middle East, East and South Africa and…

Civil forensic psychiatry - Part 1: an overview.

PubMed

Samuels, Anthony H

2018-06-01

Objectives This paper provides an overview for general and forensic psychiatrists of the complexity and challenge of working in the civil medico-legal arena. It covers expert evidence, ethics, core concepts in civil forensic psychiatry and report writing. Conclusions Civil forensic psychiatry is an important sub-speciality component of forensic psychiatry that requires specific skills, knowledge and the ability to assist legal bodies in determining the significance of psychiatric issues.

High-Energy Astrophysics: An Overview

NASA Technical Reports Server (NTRS)

Fishman, Gerald J.

2007-01-01

High-energy astrophysics is the study of objects and phenomena in space with energy densities much greater than that found in normal stars and galaxies. These include black holes, neutron stars, cosmic rays, hypernovae and gamma-ray bursts. A history and an overview of high-energy astrophysics will be presented, including a description of the objects that are observed. Observing techniques, space-borne missions in high-energy astrophysics and some recent discoveries will also be described. Several entirely new types of astronomy are being employed in high-energy astrophysics. These will be briefly described, along with some NASA missions currently under development.

Rotavirus an emerging enteropathogen of man and animals: an overview.

PubMed

Malik, S V; Kumar, A; Bhilegaonkar, K N

1995-12-01

Rota Viral infection is recognised as a significant global public health concern causing large numbers of potentially preventable illnesses and deaths, especially among young ones of man and animals. The paper presents an overview of the epidemiology, control, treatment, virology, diagnosis and the zoonotic aspects of the problem. Problems for further research are identified.

An overview of photovoltaic applications in space

NASA Technical Reports Server (NTRS)

Wasel, Robert A.

1987-01-01

An overview is given of the uses of photovoltaic (PV) power in space. The contribution of PV systems on unmanned, low Earth orbit and inner planetary missions is noted. The development of PV technology along the two paths of high efficiency and high power is discussed. The importance of increasing the service life of PV systems is covered.

Digital Libraries and Digitisation: An Overview and Critique

ERIC Educational Resources Information Center

Rikowski, Ruth

2008-01-01

This article provides an overview of some of the main areas surrounding the broad topic of "Digital Libraries". This includes the advantages and costs of digitisation; the traditional and digital library; the library community and digitisation; and an examination of various digital library projects. It is not exhaustive, but hopefully, it provides…

Computational Aeroacoustics: An Overview

NASA Technical Reports Server (NTRS)

Tam, Christopher K. W.

2003-01-01

An overview of recent advances in computational aeroacoustics (CAA) is presented. CAA algorithms must not be dispersive and dissipative. It should propagate waves supported by the Euler equations with the correct group velocities. Computation domains are inevitably finite in size. To avoid the reflection of acoustic and other outgoing waves at the boundaries of the computation domain, it is required that special boundary conditions be imposed at the boundary region. These boundary conditions either absorb all the outgoing waves without reflection or allow the waves to exit smoothly. High-order schemes, invariably, supports spurious short waves. These spurious waves tend to pollute the numerical solution. They must be selectively damped or filtered out. All these issues and relevant computation methods are briefly reviewed. Jet screech tones are known to have caused structural fatigue in military combat aircrafts. Numerical simulation of the jet screech phenomenon is presented as an example of a successful application of CAA.

Open peer review at four STEM journals: an observational overview.

PubMed

Ford, Emily

2015-01-01

Open peer review, peer review where authors' and reviewers' identities are disclosed to one another, is a growing trend in scholarly publishing. Through observation of four journals in STEM disciplines, PLOS One, Atmospheric Chemistry & Physics, PeerJ, and F1000Research, an observational overview is conducted. The overview relies on defined characteristics of open peer review. Results show that despite differing open peer review implementations, each journal retains editorial involvement in scholarly publishing. Further, the analysis shows that only one of these implementations is fully transparent in its peer review and decision making process. Finally, the overview contends that journals should clearly outline peer review and editorial processes in order to allow for open peer review to be better understood and adopted by authors, reviewers, editors, and readers of science communications.

EMERGING CONTAMINANTS: AN OVERVIEW OF ON-GOING RESEARCH

EPA Science Inventory

This presentation covers an overview of research on emerging contaminants on-going at

U.S. EPA's National Exposure Research Laboratory in Las Vegas. Due to the

improvements and sophistication of recent analytical instruments, increasing numbers of

chemicals a...

Lymphohematopoietic Cancers Induced by Chemicals and Other Agents: Overview and Implications for Risk Assessment (Final Report)

EPA Science Inventory

EPA announced the release of the final report, Lymphohematopoietic Cancers Induced by Chemicals and Other Agents: Overview and Implications for Risk Assessment . This report provides an overview of the types of mechanisms underlying the lymphohematopoietic cancers induc...

Generative Adversarial Networks: An Overview

NASA Astrophysics Data System (ADS)

Creswell, Antonia; White, Tom; Dumoulin, Vincent; Arulkumaran, Kai; Sengupta, Biswa; Bharath, Anil A.

2018-01-01

Generative adversarial networks (GANs) provide a way to learn deep representations without extensively annotated training data. They achieve this through deriving backpropagation signals through a competitive process involving a pair of networks. The representations that can be learned by GANs may be used in a variety of applications, including image synthesis, semantic image editing, style transfer, image super-resolution and classification. The aim of this review paper is to provide an overview of GANs for the signal processing community, drawing on familiar analogies and concepts where possible. In addition to identifying different methods for training and constructing GANs, we also point to remaining challenges in their theory and application.

Computer-assisted cartography: an overview.

USGS Publications Warehouse

Guptill, S.C.; Starr, L.E.

1984-01-01

An assessment of the current status of computer-assisted cartography, in part, is biased by one's view of the cartographic process as a whole. From a traditional viewpoint we are concerned about automating the mapping process; from a progressive viewpoint we are concerned about using the tools of computer science to convey spatial information. On the surface these viewpoints appear to be in opposition. However, it is postulated that in the final analysis, they face the same goal. This overview uses the perspectives from two viewpoints to depict the current state of computer-assisted cartography and speculate on future goals, trends, and challenges.-Authors

An Energy Overview of the Kingdom of Thailand

DOE Office of Scientific and Technical Information (OSTI.GOV)

anon.

The DOE Office of Fossil Energy is maintaining a web site that is meant to provide useful business- and energy-related information about countries and regions of the world for exporters, project developers, and researchers. The site consists of more than 130 country pages (organized into seven different world regions), with each country page having its own set of links to information sources about that country. There are also more than 30 Country Energy Overviews at the web site -- each of these is a comprehensive review of a specific country's entire energy situation, including sections on Energy Policy, Oil, Naturalmore » Gas, Coal, Hydroelectric/Renewables, Nuclear Power, Energy Transmission Infrastructure, Electricity, Electric Industry Overview, Environmental Activities, Privatization, Trade, and Economic Situation. The specific country highlighted in this Country Energy Overview is Thailand. The site is designed to be dynamic. Updates to the overviews will be made as need and resource s permit.« less

An Energy Overview of the Republic of Egypt

DOE Office of Scientific and Technical Information (OSTI.GOV)

anon.

2003-10-17

The DOE Office of Fossil Energy is maintaining a web site that is meant to provide useful business- and energy-related information about countries and regions of the world for exporters, project developers, and researchers. The site consists of more than 130 country pages (organized into seven different world regions), with each country page having its own set of links to information sources about that country. There are also more than 30 Country Energy Overviews at the web site -- each of these is a comprehensive review of a specific country's entire energy situation, including sections on Energy Policy, Oil, Naturalmore » Gas, Coal, Hydroelectric/Renewables, Nuclear Power, Energy Transmission Infrastructure, Electricity, Electric Industry Overview, Environmental Activities, Privatization, Trade, and Economic Situation. The specific country highlighted in this Country Energy Overview is Egypt. The site is designed to be dynamic. Updates to the overviews will be made as need and resources permit.« less

An Energy Overview of the Republic of Poland

DOE Office of Scientific and Technical Information (OSTI.GOV)

anon.

The DOE Office of Fossil Energy is maintaining a web site that is meant to provide useful business- and energy-related information about countries and regions of the world for exporters, project developers, and researchers. The site consists of more than 130 country pages (organized into seven different world regions), with each country page having its own set of links to information sources about that country. There are also more than 30 Country Energy Overviews at the web site -- each of these is a comprehensive review of a specific country's entire energy situation, including sections on Energy Policy, Oil, Naturalmore » Gas, Coal, Hydroelectric/Renewables, Nuclear Power, Energy Transmission Infrastructure, Electricity, Electric Industry Overview, Environmental Activities, Privatization, Trade, and Economic Situation. The specific country highlighted in this Country Energy Overview is Poland. The site is designed to be dynamic. Updates to the overviews will be made as need and resources permit.« less

An Overview of Snow Photochemistry: Evidence, Mechanisms and Impacts

NASA Technical Reports Server (NTRS)

Grannas, A. M.; Jones, A. E.; Dibb, J.; Ammann, M.; Anastasio, C.; Beine, H. J.; Bergin, M.; Bottenheim, J.; Boxe, C. S.; Carver, G.;

Surgical Scar Revision: An Overview

PubMed Central

Garg, Shilpa; Dahiya, Naveen; Gupta, Somesh

2014-01-01

Scar formation is an inevitable consequence of wound healing from either a traumatic or a surgical intervention. The aesthetic appearance of a scar is the most important criteria to judge the surgical outcome. An understanding of the anatomy and wound healing along with experience, meticulous planning and technique can reduce complications and improve the surgical outcome. Scar revision does not erase a scar but helps to make it less noticeable and more acceptable. Both surgical and non-surgical techniques, used either alone or in combination can be used for revising a scar. In planning a scar revision surgeon should decide on when to act and the type of technique to use for scar revision to get an aesthetically pleasing outcome. This review article provides overview of methods applied for facial scar revision. This predominantly covers surgical methods. PMID:24761092

An Overview of Biofield Devices

PubMed Central

Muehsam, David; Chevalier, Gaétan; Barsotti, Tiffany

2015-01-01

Advances in biophysics, biology, functional genomics, neuroscience, psychology, psychoneuroimmunology, and other fields suggest the existence of a subtle system of “biofield” interactions that organize biological processes from the subatomic, atomic, molecular, cellular, and organismic to the interpersonal and cosmic levels. Biofield interactions may bring about regulation of biochemical, cellular, and neurological processes through means related to electromagnetism, quantum fields, and perhaps other means of modulating biological activity and information flow. The biofield paradigm, in contrast to a reductionist, chemistry-centered viewpoint, emphasizes the informational content of biological processes; biofield interactions are thought to operate in part via low-energy or “subtle” processes such as weak, nonthermal electromagnetic fields (EMFs) or processes potentially related to consciousness and nonlocality. Biofield interactions may also operate through or be reflected in more well-understood informational processes found in electroencephalographic (EEG) and electrocardiographic (ECG) data. Recent advances have led to the development of a wide variety of therapeutic and diagnostic biofield devices, defined as physical instruments best understood from the viewpoint of a biofield paradigm. Here, we provide a broad overview of biofield devices, with emphasis on those devices for which solid, peer-reviewed evidence exists. A subset of these devices, such as those based upon EEG- and ECG-based heart rate variability, function via mechanisms that are well understood and are widely employed in clinical settings. Other device modalities, such a gas discharge visualization and biophoton emission, appear to operate through incompletely understood mechanisms and have unclear clinical significance. Device modes of operation include EMF-light, EMF-heat, EMF-nonthermal, electrical current, vibration and sound, physical and mechanical, intentionality and nonlocality

An Overview of Biofield Devices.

PubMed

Muehsam, David; Chevalier, Gaétan; Barsotti, Tiffany; Gurfein, Blake T

2015-11-01

Advances in biophysics, biology, functional genomics, neuroscience, psychology, psychoneuroimmunology, and other fields suggest the existence of a subtle system of "biofield" interactions that organize biological processes from the subatomic, atomic, molecular, cellular, and organismic to the interpersonal and cosmic levels. Biofield interactions may bring about regulation of biochemical, cellular, and neurological processes through means related to electromagnetism, quantum fields, and perhaps other means of modulating biological activity and information flow. The biofield paradigm, in contrast to a reductionist, chemistry-centered viewpoint, emphasizes the informational content of biological processes; biofield interactions are thought to operate in part via low-energy or "subtle" processes such as weak, nonthermal electromagnetic fields (EMFs) or processes potentially related to consciousness and nonlocality. Biofield interactions may also operate through or be reflected in more well-understood informational processes found in electroencephalographic (EEG) and electrocardiographic (ECG) data. Recent advances have led to the development of a wide variety of therapeutic and diagnostic biofield devices, defined as physical instruments best understood from the viewpoint of a biofield paradigm. Here, we provide a broad overview of biofield devices, with emphasis on those devices for which solid, peer-reviewed evidence exists. A subset of these devices, such as those based upon EEG- and ECG-based heart rate variability, function via mechanisms that are well understood and are widely employed in clinical settings. Other device modalities, such a gas discharge visualization and biophoton emission, appear to operate through incompletely understood mechanisms and have unclear clinical significance. Device modes of operation include EMF-light, EMF-heat, EMF-nonthermal, electrical current, vibration and sound, physical and mechanical, intentionality and nonlocality, gas and

An Overview of an Experimental Demonstration Aerotow Program

NASA Technical Reports Server (NTRS)

Murray, James E.; Bowers, Albion H.; Lokos, William A.; Peters, Todd L.; Gera, Joseph

1998-01-01

An overview of an experimental demonstration of aerotowing a delta-wing airplane with low-aspect ratio and relatively high wing loading is presented. Aerotowing of future space launch configurations is a new concept, and the objective of the work described herein is to demonstrate the aerotow operation using an airplane configuration similar to conceptual space launch vehicles. Background information on the use of aerotow for a space launch vehicle is presented, and the aerotow system used in this demonstration is described. The ground tests, analytical studies, and flight planning used to predict system behavior and to enhance flight safety are detailed. The instrumentation suite and flight test maneuvers flown are discussed, preliminary performance is assessed, and flight test results are compared with the preflight predictions.

Stimuli Responsive Ionogels for Sensing Applications—An Overview

PubMed Central

Kavanagh, Andrew; Byrne, Robert; Diamond, Dermot; Fraser, Kevin J.

2012-01-01

This overview aims to summarize the existing potential of “Ionogels” as a platform to develop stimuli responsive materials. Ionogels are a class of materials that contain an Ionic Liquid (IL) confined within a polymer matrix. Recently defined as “a solid interconnected network spreading throughout a liquid phase”, the ionogel therefore combines the properties of both its solid and liquid components. ILs are low melting salts that exist as liquids composed entirely of cations and anions at or around 100 °C. Important physical properties of these liquids such as viscosity, density, melting point and conductivity can be altered to suit a purpose by choice of the cation/anion. Here we provide an overview to highlight the literature thus far, detailing the encapsulation of IL and responsive materials within these polymeric structures. Exciting applications in the areas of optical and electrochemical sensing, solid state electrolytes and actuating materials shall be discussed. PMID:24957961

The planned Alaska SAR Facility - An overview

NASA Technical Reports Server (NTRS)

Carsey, Frank; Weeks, Wilford

1987-01-01

The Alaska SAR Facility (ASF) is described in an overview fashion. The facility consists of three major components, a Receiving Ground System, a SAR Processing System and an Analysis and Archiving System; the ASF Program also has a Science Working Team and the requisite management and operations systems. The ASF is now an approved and fully funded activity; detailed requirements and science background are presented for the facility to be implemented for data from the European ERS-1, the Japanese ERS-1 and Radarsat.

Visual Masking in Schizophrenia: Overview and Theoretical Implications

PubMed Central

Green, Michael F.; Lee, Junghee; Wynn, Jonathan K.; Mathis, Kristopher I.

2011-01-01

Visual masking provides several key advantages for exploring the earliest stages of visual processing in schizophrenia: it allows for control over timing at the millisecond level, there are several well-supported theories of the underlying neurobiology of visual masking, and it is amenable to examination by electroencephalogram (EEG) and functional magnetic resonance imaging (fMRI). In this paper, we provide an overview of the visual masking impairment schizophrenia, including the relevant theoretical mechanisms for masking impairment. We will discuss its relationship to clinical symptoms, antipsychotic medications, diagnostic specificity, and presence in at-risk populations. As part of this overview, we will cover the neural correlates of visual masking based on recent findings from EEG and fMRI. Finally, we will suggest a possible mechanism that could explain the patterns of masking findings and other visual processing findings in schizophrenia. PMID:21606322

Neural correlates of math anxiety – an overview and implications

PubMed Central

Artemenko, Christina; Daroczy, Gabriella; Nuerk, Hans-Christoph

2015-01-01

Math anxiety is a common phenomenon which can have a negative impact on numerical and arithmetic performance. However, so far little is known about the underlying neurocognitive mechanisms. This mini review provides an overview of studies investigating the neural correlates of math anxiety which provide several hints regarding its influence on math performance: while behavioral studies mostly observe an influence of math anxiety on difficult math tasks, neurophysiological studies show that processing efficiency is already affected in basic number processing. Overall, the neurocognitive literature suggests that (i) math anxiety elicits emotion- and pain-related activation during and before math activities, (ii) that the negative emotional response to math anxiety impairs processing efficiency, and (iii) that math deficits triggered by math anxiety may be compensated for by modulating the cognitive control or emotional regulation network. However, activation differs strongly between studies, depending on tasks, paradigms, and samples. We conclude that neural correlates can help to understand and explore the processes underlying math anxiety, but the data are not very consistent yet. PMID:26388824

Conformational Sampling in Template-Free Protein Loop Structure Modeling: An Overview

PubMed Central

Li, Yaohang

2013-01-01

Accurately modeling protein loops is an important step to predict three-dimensional structures as well as to understand functions of many proteins. Because of their high flexibility, modeling the three-dimensional structures of loops is difficult and is usually treated as a “mini protein folding problem” under geometric constraints. In the past decade, there has been remarkable progress in template-free loop structure modeling due to advances of computational methods as well as stably increasing number of known structures available in PDB. This mini review provides an overview on the recent computational approaches for loop structure modeling. In particular, we focus on the approaches of sampling loop conformation space, which is a critical step to obtain high resolution models in template-free methods. We review the potential energy functions for loop modeling, loop buildup mechanisms to satisfy geometric constraints, and loop conformation sampling algorithms. The recent loop modeling results are also summarized. PMID:24688696

Conformational sampling in template-free protein loop structure modeling: an overview.

PubMed

Li, Yaohang

2013-01-01

Accurately modeling protein loops is an important step to predict three-dimensional structures as well as to understand functions of many proteins. Because of their high flexibility, modeling the three-dimensional structures of loops is difficult and is usually treated as a "mini protein folding problem" under geometric constraints. In the past decade, there has been remarkable progress in template-free loop structure modeling due to advances of computational methods as well as stably increasing number of known structures available in PDB. This mini review provides an overview on the recent computational approaches for loop structure modeling. In particular, we focus on the approaches of sampling loop conformation space, which is a critical step to obtain high resolution models in template-free methods. We review the potential energy functions for loop modeling, loop buildup mechanisms to satisfy geometric constraints, and loop conformation sampling algorithms. The recent loop modeling results are also summarized.

[Cardiopulmonary syndrome in hantavirus infection (an overview)].

PubMed

Mukhetdinova, G A; Fazlyeva, R M; Fazlyev, M M

2012-06-01

The article provides an overview of domestic and foreign literature on modern aspects of hantavirus infection. Hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome have a high epidemiological significance for Russia's Armed Forces and the armies of many foreign countries. Current knowledge of the various manifestations of the disease contribute to the improvement of diagnosis and timely delivery of medical and preventive measures.

Online Student Services: An Overview of the Provision.

ERIC Educational Resources Information Center

McNickle, Cathy

This paper presents an overview of online student services being used by 19 vocational education and training (VET) and higher education institutions in Australia. Information was gathered though site visits between July and September 2000 about online support services for prospective students, enrolling students, enrolled students, and graduating…

An overview of Laser-Produced Relativistic Positrons in the Laboratory

NASA Astrophysics Data System (ADS)

Edghill, Brandon; Williams, Gerald; Chen, Hui; Beg, Farhat

2017-10-01

The production of relativistic positrons using ultraintense lasers can facilitate studies of fundamental pair plasma science in the relativistic regime and laboratory studies of scaled energetic astrophysical mechanisms such as gamma ray bursts. The positron densities and spatial scales required for these applications, however, are larger than current capabilities. Here, we present an overview of the experimental laser-produced positron results and their respective modeling for both the direct laser-irradiated process and the indirect process (laser wakefield accelerated electrons irradiating a high-Z converter). Conversion efficiency into positrons and positron beam characteristics are compared, including total pair yield, mean energy, angular divergence, and inferred pair density for various laser and target conditions. Prospects towards increasing positron densities and beam repetition rates will also be discussed. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344, and funded by LDRD (#17-ERD-010).

Membrane Technologies in Wine Industry: An Overview.

PubMed

El Rayess, Youssef; Mietton-Peuchot, Martine

2016-09-09

Membrane processes are increasingly reported for various applications in wine industry such as microfiltration, electrodialysis, and reverse osmosis, but also emerging processes as bipolar electrodialysis and membrane contactor. Membrane-based processes are playing a critical role in the field of separation/purification, clarification, stabilization, concentration, and de-alcoholization of wine products. They begin to be an integral part of the winemaking process. This review will provide an overview of recent developments, applications, and published literature in membrane technologies applied in wine industry.

Role of Chirality in Drugs… An Overview

PubMed

Alkadi, Hourieh; Jbeily, Rajwa

2017-03-29

Stereochemistry has been occupied a great role in manufacture and development of pharmaceuti-cals. Chiral properties play an important role in the determination of pharmacological actions of the drug. In recent years, there is a considerable interest in chiral separation to isolate and examine both enantiomers. This article provides an overview about the stereochemistry and its role in drugs, and also, offers approved isolation methods for enantiomeric pairs. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Sport prostheses and prosthetic adaptations for the upper and lower limb amputees: an overview of peer reviewed literature.

PubMed

Bragaru, Mihai; Dekker, Rienk; Geertzen, Jan H B

2012-09-01

Sport prostheses are used by both upper- and lower-limb amputees while participating in sports and other physical activities. Although the number of these devices has increased over the past decade, no overview of the peer reviewed literature describing them has been published previously. Such an overview will allow specialists to choose appropriate prostheses based on available scientific evidence rather than on personal experience or preference. To provide an overview of the sport prostheses as they are described by the papers published in peer reviewed literature. Literature review. Four electronic databases were searched using free text and Medical Subject Headings (MESH) terms. Papers were included if they concerned a prosthesis or a prosthetic adaptation used in sports. Papers were excluded if they did not originate from peer reviewed sources, if they concerned prostheses for body parts other than the upper or lower limbs, if they concerned amputations distal to the wrist or ankle, or if they were written in a language other than English. Twenty-four papers were included in this study. The vast majority contained descriptive data and consisted of expert opinions and technical notes. Data concerning the energy efficiency, technical characteristics and special mechanical properties of prostheses or prosthetic adaptations for sports, other than running, are scarce.

Avalanches and plastic flow in crystal plasticity: an overview

NASA Astrophysics Data System (ADS)

Papanikolaou, Stefanos; Cui, Yinan; Ghoniem, Nasr

2018-01-01

Crystal plasticity is mediated through dislocations, which form knotted configurations in a complex energy landscape. Once they disentangle and move, they may also be impeded by permanent obstacles with finite energy barriers or frustrating long-range interactions. The outcome of such complexity is the emergence of dislocation avalanches as the basic mechanism of plastic flow in solids at the nanoscale. While the deformation behavior of bulk materials appears smooth, a predictive model should clearly be based upon the character of these dislocation avalanches and their associated strain bursts. We provide here a comprehensive overview of experimental observations, theoretical models and computational approaches that have been developed to unravel the multiple aspects of dislocation avalanche physics and the phenomena leading to strain bursts in crystal plasticity.

Bullying in Schools: An Overview. Juvenile Justice Bulletin

ERIC Educational Resources Information Center

Seeley, Ken; Tombari, Martin L.; Bennett, Laurie J.; Dunkle, Jason B.

2011-01-01

Researchers from the National Center for School Engagement conducted a series of studies to explore the connections between bullying in schools, school attendance and engagement, and academic achievement. This bulletin provides an overview of the studies funded by the Office of Juvenile Justice and Delinquency Prevention (OJJDP), a summary of the…

An Overview of the Every Student Succeeds Act

ERIC Educational Resources Information Center

Meibaum, Debra L.

2016-01-01

This publication provides an overview of the Every Student Succeeds Act (ESSA). The following topics are covered : (1) Introductory Information, including a timelime and ESSA modifications to the No Child Left Behind Act (NCLB); (2) State Plan; 3) Statewide Accountability System, ; (4) Academic Assessments; (5) Standards; (6) School Improvement;…

An Overview of Integration and Test of the James Webb Space Telescope Integrated Science Instrument Module

NASA Technical Reports Server (NTRS)

Drury, Michael; Becker, Neil; Bos, Brent; Davila, Pamela; Frey, Bradley; Hylan, Jason; Marsh, James; McGuffey, Douglas; Novak, Maria; Ohl, Raymond;

Mechanisms underlying astringency: introduction to an oral tribology approach

NASA Astrophysics Data System (ADS)

Upadhyay, Rutuja; Brossard, Natalia; Chen, Jianshe

2016-03-01

Astringency is one of the predominant factors in the sensory experience of many foods and beverages ranging from wine to nuts. The scientific community is discussing mechanisms that explain this complex phenomenon, since there are no conclusive results which correlate well with sensory astringency. Therefore, the mechanisms and perceptual characteristics of astringency warrant further discussion and investigation. This paper gives a brief introduction of the fundamentals of oral tribology forming a basis of the astringency mechanism. It discusses the current state of the literature on mechanisms underlying astringency describing the existing astringency models. The review discusses the crucial role of saliva and its physiology which contributes significantly in astringency perception in the mouth. It also provides an overview of research concerned with the physiological and psychophysical factors that mediate the perception of this sensation, establishing the ground for future research. Thus, the overall aim of the review is to establish the critical roles of oral friction (thin-film lubrication) in the sensation of astringency and possibly of some other specific sensory features.

An overview of PM-10 base year emissions inventories

DOT National Transportation Integrated Search

1999-01-01

This report provides an overview of the Long Term Pavement Performance (LTPP) program's analysis program. Specifically, it outlines the analysis projects that will be undertaken by the Federal Highway Administration in fiscal years 1999 and 2000 and ...

Coronary Microvascular Disease in Chronic Chagas Cardiomyopathy Including an Overview on History, Pathology, and Other Proposed Pathogenic Mechanisms

PubMed Central

Rossi, Marcos A.; Tanowitz, Herbert B.; Malvestio, Lygia M.; Celes, Mara R.; Campos, Erica C.; Blefari, Valdecir; Prado, Cibele M.

2010-01-01

This review focuses on the short and bewildered history of Brazilian scientist Carlos Chagas's discovery and subsequent developments, the anatomopathological features of chronic Chagas cardiomyopathy (CCC), an overview on the controversies surrounding theories concerning its pathogenesis, and studies that support the microvascular hypothesis to further explain the pathological features and clinical course of CCC. It is our belief that knowledge of this particular and remarkable cardiomyopathy will shed light not only on the microvascular involvement of its pathogenesis, but also on the pathogenetic processes of other cardiomyopathies, which will hopefully provide a better understanding of the various changes that may lead to an end-stage heart disease with similar features. This review is written to celebrate the 100th anniversary of the discovery of Chagas disease. PMID:20824217

An Overview on Additive Manufacturing of Polymers

NASA Astrophysics Data System (ADS)

Jasiuk, Iwona; Abueidda, Diab W.; Kozuch, Christopher; Pang, Siyuan; Su, Frances Y.; McKittrick, Joanna

2018-03-01

We present an overview on additive manufacturing (AM), also called three-dimensional printing, with a focus on polymers. First, we introduce the AM concept. Next, we outline several AM processes, including their advantages and limitations, and list common polymers that are used in commercial printers. Then, we state various AM applications and present two examples. We conclude with a global view of the AM field, its challenges, and future directions.

Aromatherapy for health care: an overview of systematic reviews.

PubMed

Lee, Myeong Soo; Choi, Jiae; Posadzki, Paul; Ernst, Edzard

2012-03-01

Aromatherapy is the therapeutic use of essential oil from herbs, flowers, and other plants. The aim of this overview was to provide an overview of systematic reviews evaluating the effectiveness of aromatherapy. We searched 12 electronic databases and our departmental files without restrictions of time or language. The methodological quality of all systematic reviews was evaluated independently by two authors. Of 201 potentially relevant publications, 10 met our inclusion criteria. Most of the systematic reviews were of poor methodological quality. The clinical subject areas were hypertension, depression, anxiety, pain relief, and dementia. For none of the conditions was the evidence convincing. Several SRs of aromatherapy have recently been published. Due to a number of caveats, the evidence is not sufficiently convincing that aromatherapy is an effective therapy for any condition. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

An Overview of the Mechanism of Action of the Monoclonal Antibody Vedolizumab.

PubMed

Wyant, Tim; Fedyk, Eric; Abhyankar, Brihad

2016-12-01

Vedolizumab is a novel therapeutic monoclonal antibody recently approved for the treatment of moderately to severely active ulcerative colitis and Crohn's disease in adults who have failed at least one conventional therapy. An integrin antagonist, vedolizumab binds to the α 4 β 7 integrin which is expressed specifically by a subset of gastrointestinal-homing T lymphocytes. The binding of α 4 β 7 integrin to mucosal addressin cell adhesion molecule-1 expressed on the surface of mucosal endothelial cells is a crucial component of the gut-selective homing mechanism for lymphocytes.In contrast, other monoclonal antibodies approved for the treatment of inflammatory bowel diseases, such as tumour necrosis factor α antagonists and the integrin antagonist natalizumab, act systemically or on multiple targets to reduce inflammation.The unique gut selectivity of vedolizumab may contribute to the favourable benefit-risk profile observed in vedolizumab clinical trials. In this review, we summarise data from the preclinical development of vedolizumab and describe the current understanding of the mechanism of action as it relates to other biological therapies for inflammatory bowel disease. Copyright © 2016 European Crohn’s and Colitis Organisation (ECCO). Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

50 CFR 84.31 - An overview of the ranking criteria.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (CONTINUED) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM NATIONAL COASTAL WETLANDS CONSERVATION GRANT PROGRAM Project Selection § 84.31 An overview of the ranking criteria. (a) The primary...

NASA Ames Research Center: An Overview

NASA Technical Reports Server (NTRS)

Tu, Eugene; Yan, Jerry Chi Yiu

2017-01-01

This overview of NASA Ames Research Center is intended to give the target audience of university students a general understanding of the mission, core competencies, and research goals of NASA and Ames.

AN OVERVIEW ON PET RADIOCHEMISTRY: PART 2 - RADIOMETALS.

PubMed

Brandt, Marie; Cardinale, Jens; Aulsebrook, Margaret; Gasser, Gilles; Mindt, Thomas

2018-05-10

This continuing educational review provides an overview on radiometals used for PET. General aspects of radiometal-based radiotracers are covered and the most frequently applied metallic PET radionuclides 68 Ga, 89 Zr, and 64 Cu are highlighted with a discussion of their strengths and limitations. Copyright © 2018 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

An Overview of Teratology.

PubMed

Calado, Ana M; Dos Anjos Pires, Maria

2018-01-01

In this chapter, we provide an overview of the basic principles of teratology, beginning with its definition, the critical point for teratogenesis to occur and the most evident etiological agents to improve the understanding of this science.Teratology is a recent science that began in the early twentieth century, and has greatly improved over the recent years with the advancements in molecular biology, toxicology, animal laboratory science, and genetics, as well as the improvement on the knowledge of the environmental influences.Nevertheless, more work is required to reduce the influence of hazardous products that could be deleterious during pregnancy, thus reducing teratogenic defects in the newborn. While some teratogenic defects are attributed to their agents with certainty, the same for a lot of other such defects is lacking, necessitating consistent studies to decipher the influence of various teratogenic agents on their corresponding teratogenic defects. It is here that the laboratory animal science is of great importance both in the present and in the future.

Complementary DNA libraries: an overview.

PubMed

Ying, Shao-Yao

2004-07-01

The generation of complete and full-length cDNA libraries for potential functional assays of specific gene sequences is essential for most molecules in biotechnology and biomedical research. The field of cDNA library generation has changed rapidly in the past 10 yr. This review presents an overview of the method available for the basic information of generating cDNA libraries, including the definition of the cDNA library, different kinds of cDNA libraries, difference between methods for cDNA library generation using conventional approaches and a novel strategy, and the quality of cDNA libraries. It is anticipated that the high-quality cDNA libraries so generated would facilitate studies involving genechips and the microarray, differential display, subtractive hybridization, gene cloning, and peptide library generation.

An Overview of Space Power Systems for NASA Missions

NASA Technical Reports Server (NTRS)

Lyons, Valerie J.; Scott, John H.

2007-01-01

Power is a critical commodity for all engineering efforts and is especially challenging in the aerospace field. This paper will provide a broad brush overview of some of the immediate and important challenges to NASA missions in the field of aerospace power, for generation, energy conversion, distribution, and storage. NASA s newest vehicles which are currently in the design phase will have power systems that will be developed from current technology, but will have the challenges of being light-weight, energy-efficient, and space-qualified. Future lunar and Mars "outposts" will need high power generation units for life support and energy-intensive exploration efforts. An overview of the progress in concepts for power systems and the status of the required technologies are discussed.

Assisted reproductive technology: an overview of Cochrane Reviews.

PubMed

Farquhar, Cindy; Rishworth, Josephine R; Brown, Julie; Nelen, Willianne L D M; Marjoribanks, Jane

2015-07-15

draw conclusions due to lack of evidence.An additional 11 protocols and five titles were identified for future inclusion in this overview. This overview provides the most up to date evidence on ART cycles from systematic reviews of randomised controlled trials. Fertility treatments are costly and the stakes are high. Using the best available evidence to optimise outcomes is best practice. The evidence from this overview could be used to develop clinical practice guidelines and protocols for use in daily clinical practice, in order to improve live birth rates and reduce rates of multiple pregnancy, cycle cancellation and ovarian hyperstimulation syndrome.

Assisted reproductive technology: an overview of Cochrane reviews.

PubMed

Farquhar, Cindy; Rishworth, Josephine R; Brown, Julie; Nelen, Willianne L D M; Marjoribanks, Jane

2014-12-23

due to lack of evidence.An additional 11 protocols and one title were identified for future inclusion in this overview. This overview provides the most up to date evidence on ART cycles from systematic reviews of randomised controlled trials. Fertility treatments are costly and the stakes are high. Using the best available evidence to optimise outcomes is best practice. The evidence from this overview could be used to develop clinical practice guidelines and protocols for use in daily clinical practice, in order to improve live birth rates and reduce rates of multiple pregnancy, cycle cancellation and ovarian hyperstimulation syndrome.

Assisted reproductive technology: an overview of Cochrane Reviews.

PubMed

Farquhar, Cindy; Rishworth, Josephine R; Brown, Julie; Nelen, Willianne L D M; Marjoribanks, Jane

2013-08-22

lack of evidence.An additional 15 protocols and two titles were identified for future inclusion in this overview. This overview provides the most up to date evidence on ART cycles from systematic reviews of randomised controlled trials. Fertility treatments are costly and the stakes are high. Using the best available evidence to optimise outcomes is best practice. The evidence from this overview could be used to develop clinical practice guidelines and protocols for use in daily clinical practice, in order to improve live birth rates and reduce rates of multiple pregnancy, cycle cancellation and ovarian hyperstimulation syndrome.

An Overview of Combustion Mechanisms and Flame Structures for Advanced Solid Propellants

NASA Technical Reports Server (NTRS)

Beckstead, M. W.

2000-01-01

Ammonium perchlorate (AP) and cyclotretamethylenetetranitramine (HMX) are two solid ingredients often used in modern solid propellants. Although these two ingredients have very similar burning rates as monopropellants, they lead to significantly different characteristics when combined with binders to form propellants. Part of the purpose of this paper is to relate the observed combustion characteristics to the postulated flame structures and mechanisms for AP and HMX propellants that apparently lead to these similarities and differences. For AP composite, the primary diffusion flame is more energetic than the monopropellant flame, leading to an increase in burning rate over the monopropellant rate. In contrast the HMX primary diffusion flame is less energetic than the HMX monopropellant flame and ultimately leads to a propellant rate significantly less than the monopropellant rate in composite propellants. During the past decade the search for more energetic propellants and more environmentally acceptable propellants is leading to the development of propellants based on ingredients other than AP and HMX. The objective of this paper is to utilize the more familiar combustion characteristics of AP and HMX containing propellants to project the combustion characteristics of propellants made up of more advanced ingredients. The principal conclusion reached is that most advanced ingredients appear to burn by combustion mechanisms similar to HMX containing propellants rather than AP propellants.

An Archeological Overview and Management Plan for the Harry Diamond Laboratories, Adelphi, Maryland.

DTIC Science & Technology

1985-07-01

WORK ON HARRY DIAMOND LABORATORY- ADELPHI, MARYLAND A number of prehistoric and historic sites have been reported in the vicinity of HDLA. Attempts...AD-Rftl 054 AN ARCHEOLOGICAL OVERVIEW AND NANAGENENT PLAN FOR THE Sui HARRY DIAMOND LABORATORIES ADELPHI NARYLRNDCU) U NLRSIFEDENYIROSPHERE CO NEW...An Archeological Overview and Management Plan r ifor the Harry Diamond Laboratories - Adelphi, Maryland Under Contract CX4000-3-0018 with the National

Getting Across the Cell Membrane: An Overview for Small Molecules, Peptides, and Proteins

PubMed Central

Yang, Nicole J.; Hinner, Marlon J.

2016-01-01

The ability to efficiently access cytosolic proteins is desired in both biological research and medicine. However, targeting intracellular proteins is often challenging, because to reach the cytosol, exogenous molecules must first traverse the cell membrane. This review provides a broad overview of how certain molecules are thought to cross this barrier, and what kinds of approaches are being made to enhance the intracellular delivery of those that are impermeable. We first discuss rules that govern the passive permeability of small molecules across the lipid membrane, and mechanisms of membrane transport that have evolved in nature for certain metabolites, peptides, and proteins. Then, we introduce design strategies that have emerged in the development of small molecules and peptides with improved permeability. Finally, intracellular delivery systems that have been engineered for protein payloads are surveyed. Viewpoints from varying disciplines have been brought together to provide a cohesive overview of how the membrane barrier is being overcome. PMID:25560066

An Overview of Cloud Computing in Distributed Systems

NASA Astrophysics Data System (ADS)

Divakarla, Usha; Kumari, Geetha

2010-11-01

Cloud computing is the emerging trend in the field of distributed computing. Cloud computing evolved from grid computing and distributed computing. Cloud plays an important role in huge organizations in maintaining huge data with limited resources. Cloud also helps in resource sharing through some specific virtual machines provided by the cloud service provider. This paper gives an overview of the cloud organization and some of the basic security issues pertaining to the cloud.

An Overview of Outpatient Treatment of Adolescent Substance Abuse

ERIC Educational Resources Information Center

Galanter, Marc; Glickman, Linda; Singer, David

2007-01-01

This paper reviews the literature on ambulatory substance abuse treatment for adolescents, including brief intervention, Twelve-Step-based outpatient treatment, family-based treatment, cognitive behavioral therapy, and pharmacologic treatment. An overview of socially and culturally specific strategies is also included. The diversity of settings…

Neptune aerocapture mission and spacecraft design overview

NASA Technical Reports Server (NTRS)

Bailey, Robert W.; Hall, Jeff L.; Spliker, Tom R.; O'Kongo, Nora

2004-01-01

A detailed Neptune aerocapture systems analysis and spacecraft design study was performed as part of NASA's In-Space Propulsion Program. The primary objectives were to assess the feasibility of a spacecraft point design for a Neptune/Triton science mission. That uses aerocapture as the Neptune orbit insertion mechanism. This paper provides an overview of the science, mission and spacecraft design resulting from that study.

[The impact of consumer behavior on the development of overweight children. An overview].

PubMed

Reisch, L A; Gwozdz, W

2010-07-01

The goal of this article is to provide an overview of internal and external factors influencing childhood obesity. Overweight and obese children are more likely to become overweight and obese adults with the well-known negative psychological, social, and economic consequences. Politics and research are searching for efficient prevention and intervention strategies. Consumer research helps to better understand the underlying mechanisms and feedback loops. Increasingly, children's complex and multilayered "obesogenic" environment is held responsible for the increasing number of overweight children. Based on an ecological model, the paper explores the scientific evidence of these environmental factors on an individual, an interpersonal (i.e., family, peers), as well as on a community level (i.e., the physical environment). Furthermore, it looks at societal factors, such as media influence, advertising, product offers, and consumer policies. It concludes that access, affordability, and availability of healthy diets and lifestyles are crucial factors to develop and sustain healthy lifestyles. Implications for consumer and corporate policy are drawn.

An overview of measurement solutions for digital systems

NASA Astrophysics Data System (ADS)

Lemke, D.

An overview of digital measurement solutions is presented. A summary of the digital instrumentation that is currently available on the commercial market is given. The technology trends that are driving commercial instrumentation suppliers to provide newer and more advanced features and better measurement solutions for the future is reviewed. The implications of developments in design automation for electrical engineers is discussed.

An Overview of Recent Advances in Event-Triggered Consensus of Multiagent Systems.

PubMed

Ding, Lei; Han, Qing-Long; Ge, Xiaohua; Zhang, Xian-Ming

2018-04-01

Event-triggered consensus of multiagent systems (MASs) has attracted tremendous attention from both theoretical and practical perspectives due to the fact that it enables all agents eventually to reach an agreement upon a common quantity of interest while significantly alleviating utilization of communication and computation resources. This paper aims to provide an overview of recent advances in event-triggered consensus of MASs. First, a basic framework of multiagent event-triggered operational mechanisms is established. Second, representative results and methodologies reported in the literature are reviewed and some in-depth analysis is made on several event-triggered schemes, including event-based sampling schemes, model-based event-triggered schemes, sampled-data-based event-triggered schemes, and self-triggered sampling schemes. Third, two examples are outlined to show applicability of event-triggered consensus in power sharing of microgrids and formation control of multirobot systems, respectively. Finally, some challenging issues on event-triggered consensus are proposed for future research.

Euthanasia: an overview and the jewish perspective.

PubMed

Gesundheit, Benjamin; Steinberg, Avraham; Glick, Shimon; Or, Reuven; Jotkovitz, Alan

2006-10-01

End-of-life care poses fundamental ethical problems to clinicians. Defining euthanasia is a difficult and complex task, which causes confusion in its practical clinical application. Over the course of history, abuse of the term has led to medical atrocities. Familiarity with the relevant bioethical issues and the development of practical guidelines might improve clinical performance. To define philosophical concepts, to present historical events, to discuss the relevant attitudes in modern bioethics and law that may be helpful in elaborating practical guidelines for clinicians regarding euthanasia and end-of-life care. Concepts found in the classic sources of Jewish tradition might shed additional light on the issue and help clinicians in their decision-making process. An historical overview defines the concepts of active versus passive euthanasia, physician-assisted suicide and related terms. Positions found in classical Jewish literature are presented and analyzed with their later interpretations. The relevance and application in modern clinical medicine of both the general and Jewish approaches are discussed. The overview of current bioethical concepts demonstrates the variety of approaches in western culture and legal systems. Philosophically and conceptually, there is a crucial distinction between active and passive euthanasia. The legitimacy of active euthanasia has been the subject of major controversy in recent times in various countries and religious traditions. The historical overview and the literature review demonstrate the need to provide clearer definitions of the concepts relating to euthanasia, for in the past the term has led to major confusion and uncontrolled abuse. Bioethical topics should, therefore, be included in medical training and continuing education. There are major debates and controversies regarding the current clinical and legal approaches. We trust that classical Jewish sources might contribute to the establishment of clinical

An Overview of the Glass Transition Temperature of Synthetic Polymers.

ERIC Educational Resources Information Center

Beck, Keith R.; And Others

1984-01-01

Presents an overview of the glass-to-rubber transition, what it is, why it is important, and the major factors that influence it. Indicates that this information should be incorporated into chemistry curricula. (JN)

An Overview of Landfill Gas Energy in the United States

EPA Pesticide Factsheets

This page provides an overview of the current landfill gas (LFG) energy industry including background information on LFG and why EPA formed LMOP, charts and data, helpful links to more information, and project case studies.

Methoxyflurane: I. An overview. II. An abstracted literature collection, 1947--1976

DOE Office of Scientific and Technical Information (OSTI.GOV)

Waters, E.M.; Ricci, B.E.

1977-07-01

Evidence presented in the literature suggests that methoxyflurane (Penthrane) (MOF) is a potent and efficacious anesthetic. At the same time, however, observed adverse reactions indicate that additional data are needed to determine the feasibility for continued widespread use of MOF. Experimental and clinical evidence clearly demonstrates that the ionic metabolites of MOF (fluoride and oxalate ions) are the toxic moieties responsible for the resultant physiologic maladies. This report on methoxyflurane is comprised of an overview and an abstracted literature collection.

An Overview of the Solar-C Mission

NASA Astrophysics Data System (ADS)

Lemen, J. R.; Tarbell, T. D.; Cirtain, J. W.; DeLuca, E. E.; Doschek, G. A.

2013-12-01

Solar-C is a new mission in solar and heliospheric physics that is being proposed to JAXA for launch in 2020. It will be led by Japan with major contributions from the US and Europe. The main scientific objectives of the mission are to: * Determine the properties and evolution of the three dimensional magnetic field, especially on small spatial scales, using direct spectro-polarimetric measurements in the photosphere and chromosphere, and accurate model extrapolations and dynamic simulations into the corona that are based, for the first time, on boundary fields observed in a low plasma beta region; * Observe and understand fundamental physical processes such as magnetic reconnection, magneto-hydrodynamic waves, shocks, turbulence, and plasma instabilities * Reveal the mechanisms responsible for the heating and dynamics of the chromosphere and corona and the acceleration of the solar wind, and understand how plasma and energy are transferred between different parts of the solar atmosphere; * Determine the physical origin of the large-scale explosions and eruptions (flares, jets, and CMEs) that drive short-term solar, heliospheric, and geospace variability. To achieve the science objectives, Solar-C will deploy a carefully coordinated suite of three complementary instruments: the Solar Ultra-violet Visible and IR Telescope (SUVIT), the high-throughput EUV Spectroscopic Telescope (EUVST), and an X-ray Imaging Telescope/Extreme Ultraviolet Telescope (XIT). For the first time, it will simultaneously observe the entire atmosphere---photosphere, chromosphere, transition region, and corona---and do so with essentially the same spatial and temporal resolution at all locations. As is the case for other solar observatories, the Solar-C mission will have an open data policy. We provide an overview of the mission and its contributions to the future of solar physics and space weather research.

An Overview of NASA Automotive Component Reliability Studies

NASA Technical Reports Server (NTRS)

Sampson, Michael J.

2016-01-01

The results of NASAs studies into the appropriateness of using US Automotive electronic parts in NASA spaceflight systems will be presented. The first part of the presentation provides an overview of the United States Automotive Electronics Councils AECQ standardization program, the second part provides a summary of the results of NASAs procurement and testing experiences and other lessons learned along with preliminary test results.

An Overview Of NASA Automotive Component Reliability Studies

NASA Technical Reports Server (NTRS)

Sampson, Michael J.

2016-01-01

The results of NASAs studies into the appropriateness of using US Automotive electronic parts in NASA spaceflight systems will be presented. The first part of the presentation provides an overview of the United States Automotive Electronics Councils AECQ standardization program, the second part provides a summary of the results of NASAs procurement and testing experiences and other lessons learned along with preliminary test results.

The redwood project: An overview

NASA Technical Reports Server (NTRS)

Cheatham, Sam

1993-01-01

Redwood is a new generation tape subsystem now under development at StorageTek using helical scan technology. This library based storage subsystem is designed for the high performance, deep archival market. The topics are presented in viewgraph form and include the following: subsystem overview, media standards, Redwood developed tape, D3 helical recording format, Redwood cartridge, host software for Redwood libraries, and market opportunities.

Contemporary health care economics: an overview.

PubMed

McLaughlin, Nancy; Ong, Michael K; Tabbush, Victor; Hagigi, Farhad; Martin, Neil A

2014-11-01

Economic evaluations provide a decision-making framework in which outcomes (benefits) and costs are assessed for various alternative options. Although the interest in complete and partial economic evaluations has increased over the past 2 decades, the quality of studies has been marginal due to methodological challenges or incomplete cost determination. This paper provides an overview of the main types of complete and partial economic evaluations, reviews key methodological elements to be considered for any economic evaluation, and reviews concepts of cost determination. The goal is to provide the clinician neurosurgeon with the knowledge and tools needed to appraise published economic evaluations and to direct high-quality health economic evaluations.

Business Ownership and Management: An Overview.

ERIC Educational Resources Information Center

Olivas, Louis, Ed.

1990-01-01

Includes six articles: "Overview" (Olivas); "Preparing Women for Entrepreneurial Opportunities" (Ownby, Rhea); "The Business Plan: Key to Realism in Teaching Entrepreneurship" (Smith, Steward); "In Search of Praise" (Frame); "Communication and the Entrepreneur" (Inman); and "Preparing Potential Entrepreneurs for Tomorrow's World" (Clodfelter).…

Economic Overview, 1996.

ERIC Educational Resources Information Center

Saskatchewan Inst. of Applied Science and Technology, Saskatoon.

This report provides an overview of economic trends and their effect on labor market training needs in Saskatchewan. Following a brief introduction, part 2 provides an overview of international economic trends, including data on world demographics, while part 3 examines the Canadian economy, focusing on job stability and the employment of…

An overview of the Communications Technology Satellite (CTS) project

NASA Technical Reports Server (NTRS)

Rapp, W.; Ogden, D.; Wright, D.

1982-01-01

The Communications Technology Satellite (CTS) project is reviewed. A technical description of the CTS spacecraft and its cognate hardware and operations is included. A historical treatise of the CTS project is provided. Also presented is an overview of the CTS experiments and demonstrations conducted during the course of the project.

Factors That Drive RTO Performance: An Overview. Synthesis Report

ERIC Educational Resources Information Center

Misko, Josie

2017-01-01

This paper provides an overview of recent research on the factors that drive the performance of registered training organisations (RTOs), with a view to identifying areas for future research. Initially it explores the drivers of RTO performance; then discusses findings from available literature from Australia and from overseas, and discusses some…

Retail video analytics: an overview and survey

NASA Astrophysics Data System (ADS)

Connell, Jonathan; Fan, Quanfu; Gabbur, Prasad; Haas, Norman; Pankanti, Sharath; Trinh, Hoang

2013-03-01

Today retail video analytics has gone beyond the traditional domain of security and loss prevention by providing retailers insightful business intelligence such as store traffic statistics and queue data. Such information allows for enhanced customer experience, optimized store performance, reduced operational costs, and ultimately higher profitability. This paper gives an overview of various camera-based applications in retail as well as the state-ofthe- art computer vision techniques behind them. It also presents some of the promising technical directions for exploration in retail video analytics.

Turbulence compensation: an overview

NASA Astrophysics Data System (ADS)

van Eekeren, Adam W. M.; Schutte, Klamer; Dijk, Judith; Schwering, Piet B. W.; van Iersel, Miranda; Doelman, Niek J.

2012-06-01

In general, long range visual detection, recognition and identification are hampered by turbulence caused by atmospheric conditions. Much research has been devoted to the field of turbulence compensation. One of the main advantages of turbulence compensation is that it enables visual identification over larger distances. In many (military) scenarios this is of crucial importance. In this paper we give an overview of several software and hardware approaches to compensate for the visual artifacts caused by turbulence. These approaches are very diverse and range from the use of dedicated hardware, such as adaptive optics, to the use of software methods, such as deconvolution and lucky imaging. For each approach the pros and cons are given and it is indicated for which scenario this approach is useful. In more detail we describe the turbulence compensation methods TNO has developed in the last years and place them in the context of the different turbulence compensation approaches and TNO's turbulence compensation roadmap. Furthermore we look forward and indicate the upcoming challenges in the field of turbulence compensation.

An Overview Of Current Research At The Environmental Protection Agency

EPA Science Inventory

The purpose of this presentation is to provide an overview of the current research at the Environmental Protection Agency. FOR FURTHER INFORMATION, CONTACT ROGER B. YEARDLEY, JR., LAND REMEDIATION AND POLLUTION CONTROL DIVISION, 513-569-7548.

An overview of telemedicine.

PubMed

Baquet, C R

1997-01-01

Greater attention has been given recently to information technology and telecommunication reforms and their use for the improvement of health care service delivery. Broadly defined, telemedicine is the use of advanced telecommunications technologies for the purposes of making diagnoses, conducting research, transferring patient data, and/or improving disease management and treatment in remote areas. The emphasis is on use of telecommunications technologies at remote sites. This article provides a brief overview of telemedicine, its potential clinical applications, and the various benefits and leading issues surrounding it. It also describes selected telemedicine projects conducted at the University of Maryland School of Medicine in Baltimore.

Counseling Families of Children with Diabetes Mellitus: An Overview.

ERIC Educational Resources Information Center

Yousef, Jamal M. S.

1995-01-01

The impact that counseling can have on a family with a child with diabetes mellitus is discussed. The benefits for the child's psychosocial adjustment and development are highlighted. An overview of the challenges a family with a diabetic child faces is provided and the counselor's role in assisting such families is emphasized. (CR)

The Air Force Advanced Instructional System (AIS): An Overview.

ERIC Educational Resources Information Center

Yasutake, Joseph Y.; Stobie, William H.

The Air Force Advanced Instructional System (AIS) is a prototype computer-based multimedia system for the administration and management of individualized technical training on a large scale. The paper provides an overview of the AIS: (1) its purposes and goals, (2) the background and rationale for the development approach, (3) a basic description…

Wood for energy in the Pacific Northwest: an overview.

Treesearch

James O. Howard

1979-01-01

This report presents an overview of the technology of converting wood to energy and the availability of wood. The first section describes fuel values and significant processes used to generate various energy products from wood. Physical, technical, and economic availability of the wood resource is discussed in the second section. The paper...

Atmospheric laser Doppler velocimetry - An overview

NASA Technical Reports Server (NTRS)

Bilbro, J. W.

1980-01-01

Research, development, and application of atmospheric laser Doppler velocimetry are overviewed. Consideration is given to operation principles of CO2 heterodyne systems. Global wind, pollution, V/STOL flow, and true airspeed measurements are outlined. Wind energy, dust devils, water spouts, tornadoes, and aircraft wake vortices are covered.

An Overview of USDOT Connected Vehicle Roadside Unit Research Activities

DOT National Transportation Integrated Search

2017-05-01

The USDOT Vehicle-to-Infrastructure (V2I) research program has developed this white paper to provide stakeholders with an overview of the history, background, and plans relating to V2I Roadside Unit Research, focusing on the development of Dedicated ...

Chandra Observations of Neutron Stars: An Overview

NASA Technical Reports Server (NTRS)

Weisskopf, Martin C.; Karovska, M.; Pavlov, G. G.; Zavlin, V. E.; Clarke, Tracy

2006-01-01

We present a brief review of Chandra X-ray Observatory observations of neutron stars. The outstanding spatial and spectral resolution of this great observatory have allowed for observations of unprecedented clarity and accuracy. Many of these observations have provided new insights into neutron star physics. We present an admittedly biased and overly brief overview of these observations, highlighting some new discoveries made possible by the Observatory's unique capabilities. We also include our analysis of recent multiwavelength observations of the putative pulsar and its pulsar-wind nebula in the IC 443 SNR.

Landsat 7 Science Data Processing: An Overview

NASA Technical Reports Server (NTRS)

Schweiss, Robert J.; Daniel, Nathaniel E.; Derrick, Deborah K.

2000-01-01

The Landsat 7 Science Data Processing System, developed by NASA for the Landsat 7 Project, provides the science data handling infrastructure used at the Earth Resources Observation Systems (EROS) Data Center (EDC) Landsat Data Handling Facility (DHF) of the United States Department of Interior, United States Geological Survey (USGS) located in Sioux Falls, South Dakota. This paper presents an overview of the Landsat 7 Science Data Processing System and details of the design, architecture, concept of operation, and management aspects of systems used in the processing of the Landsat 7 Science Data.

Natural Language Processing in Game Studies Research: An Overview

ERIC Educational Resources Information Center

Zagal, Jose P.; Tomuro, Noriko; Shepitsen, Andriy

2012-01-01

Natural language processing (NLP) is a field of computer science and linguistics devoted to creating computer systems that use human (natural) language as input and/or output. The authors propose that NLP can also be used for game studies research. In this article, the authors provide an overview of NLP and describe some research possibilities…

The Equinox Transition Study - An overview. [thermosphere/ionosphere dynamics

NASA Technical Reports Server (NTRS)

Carlson, H. C., Jr.; Crowley, G.

1989-01-01

An overview is presented of the Equinox Transition Study (ETS), including the historical perspective, the experimental philosophy, and the results of the analysis. The broad scientific aim of ETS is to understand the electromechanical response of the thermosphere/ionosphere system to variable high-latitude forcing. Some of the results obtained from ETS are summarized.

The Construct of Androgyny: An Overview and Implications for Research.

ERIC Educational Resources Information Center

Eman, Virginia A.; Morse, Benjamin W.

The concept of androgyny refers to the psychological wholeness of a person defined as the ability of an individual to identify with both masculine and feminine characteristics, depending on their appropriateness in various situations. This paper presents an overview of the construct of androgyny, describes the Bem Sex Role Inventory as a measure…

An overview of Japanese occupational health.

PubMed Central

Reich, M R; Frumkin, H

1988-01-01

This paper provides an overview of Japanese occupational health and evaluates the current situation from three perspectives. Major occupational health hazards are assessed using four sources of data, showing patterns similar to those found in other advanced industrial societies. Institutional structures for occupational health policy are then examined, illustrating strengths and weaknesses of the Japanese legal and administrative systems. Trade union activities are presented, indicating the constraints of enterprise unions, and the tendency for a greater orientation toward compensation than prevention. Significant occupational health problems persist among marginal workers in Japan, including women and various minority groups. The analysis demonstrates a record for occupational health in Japan considerably more mixed than the conventional view. PMID:2968056

Expert systems as applied to bridges and pavements : an overview.

DOT National Transportation Integrated Search

1986-01-01

Expert systems is a rapidly emerging new application of computers to aid decision makers in solving problems. This report gives an overview of what expert systems are and of what use they may be to a transportation department. The focus of the applic...

Si/C hybrid nanostructures for Li-ion anodes: An overview

NASA Astrophysics Data System (ADS)

Terranova, Maria Letizia; Orlanducci, Silvia; Tamburri, Emanuela; Guglielmotti, Valeria; Rossi, Marco

2014-01-01

This review article summarizes recent and increasing efforts in the development of novel Li ion cell anode nanomaterials based on the coupling of C with Si. The rationale behind such efforts is based on the fact that the Si-C coupling realizes a favourable combination of the two materials properties, such as the high lithiation capacity of Si and the mechanical and conductive properties of C, making Si/C hybrid nanomaterials the ideal candidates for innovative and improved Li-ion anodes. Together with an overview of the methodologies proposed in the last decade for material preparation, a discussion on relationship between organization at the nanoscale of the hybrid Si/C systems and battery performances is given. An emerging indication is that the enhancement of the batteries efficiency in terms of mass capacity, energy density and cycling stability, resides in the ability to arrange Si/C bi-component nanostructures in pre-defined architectures. Starting from the results obtained so far, this paper aims to indicate some emerging directions and to inspire promising routes to optimize fabrication of Si/C nanomaterials and engineering of Li-ion anodes structures. The use of Si/C hybrid nanostructures could represents a viable and effective solution to the foreseen limits of present lithium ion technology.

School Finance Reform in New Mexico, 1974. An Overview.

ERIC Educational Resources Information Center

Hale, Jim

This report provides an overview of the State school aid distribution plan passed by the New Mexico legislature in 1974. The previous school finance plan, passed in 1969, and the problems school districts experienced under that plan are briefly described, followed by a discussion of the 1974 legislation. The new plan is a weighted-pupil formula…

Clinical photography in dermatology using smartphones: An overview

PubMed Central

Ashique, K. T.; Kaliyadan, Feroze; Aurangabadkar, Sanjeev J.

2015-01-01

The smartphone is one of the biggest revolutions in the era of information technology. Its built in camera offers several advantages. Dermatologists, who handle a specialty that is inherently visual, are most benefited by this handy technology. Here in this article, we attempt to provide an overview of smartphone photography in clinical dermatology in order to help the dermatologist to get the best out of the available camera for clinical imaging and storage PMID:26009708

An Overview of NASA's Oribital Debris Environment Model

NASA Technical Reports Server (NTRS)

Matney, Mark

2010-01-01

Using updated measurement data, analysis tools, and modeling techniques; the NASA Orbital Debris Program Office has created a new Orbital Debris Environment Model. This model extends the coverage of orbital debris flux throughout the Earth orbit environment, and includes information on the mass density of the debris as well as the uncertainties in the model environment. This paper will give an overview of this model and its implications for spacecraft risk analysis.

The `advanced DIR-MCFC development' project, an overview

NASA Astrophysics Data System (ADS)

Kortbeek, P. J.; Ottervanger, R.

An overview is given of the approach and mid-term status of the joint European `Advanced DIR-MCFC Development' project, in which BCN, BG plc, GDF, ECN, Stork, Schelde and Sydkraft co-operate. Hospitals are identified as an attractive initial market for cogeneration direct internal reforming-molten carbonate fuel cell (DIR-MCFC) systems in the size of 400 kWe. Innovative system and stack design concepts are being developed for this application. The `SMARTER' system, based on DIR stacks, combines high electric efficiency and a wide operational window with optimal system simplicity and low cost.

Active control of large space structures: An introduction and overview

NASA Technical Reports Server (NTRS)

Doane, G. B., III; Tollison, D. K.; Waites, H. B.

1985-01-01

An overview of the large space structure (LSS) control system design problem is presented. The LSS is defined as a class of system, and LSS modeling techniques are discussed. Model truncation, control system objectives, current control law design techniques, and particular problem areas are discussed.

HIV vaccines in Canada: legal and ethical issues--an overview.

PubMed

Garmaise, David

2002-07-01

In July 2002 the Legal Network released an overview paper on legal and ethical issues related to an HIV vaccine in Canada. The paper, which is based on a more detailed report prepared in collaboration with the Centre for Bioethics of the Clinical Research Institute of Montréal, calls for the establishment of a Canadian HIV Vaccine Plan.

Radicalization: An Overview and Annotated Bibliography of Open-Source Literature

DTIC Science & Technology

2006-12-15

particularly with liberal, democratic, and humanistic Muslims Phares points to Jihadism as the main root cause of terrorism and suggests that defending...An Overview and Annotated Bibliography of Open-Source Literature 155 of ambiguity), epistemic and existential needs theory (need for closure...This book presents Terror Management Theory, which addresses behavioral and psychological responses to terrorist events. An existential

An overview of mechanisms of redox signaling.

PubMed

Forman, Henry Jay; Ursini, Fulvio; Maiorino, Matilde

2014-08-01

A principal characteristic of redox signaling is that it involves an oxidation-reduction reaction or covalent adduct formation between the sensor signaling protein and second messenger. Non-redox signaling may involve alteration of the second messenger as in hydrolysis of GTP by G proteins, modification of the signaling protein as in farnesylation, or simple non-covalent binding of an agonist or second messenger. The chemistry of redox signaling is reviewed here. Specifically we have described how among the so-called reactive oxygen species, only hydroperoxides clearly fit the role of a second messenger. Consideration of reaction kinetics and cellular location strongly suggests that for hydroperoxides, particular protein cysteines are the targets and that the requirements for redox signaling is that these cysteines are in microenvironments in which the cysteine is ionized to the thiolate, and a proton can be donated to form a leaving group. The chemistry described here is the same as occurs in the cysteine and selenocysteine peroxidases that are generally considered the primary defense against oxidative stress. But, these same enzymes can also act as the sensors and transducer for signaling. Conditions that would allow specific signaling by peroxynitrite and superoxide are also defined. Signaling by other electrophiles, which includes lipid peroxidation products, quinones formed from polyphenols and other metabolites also involves reaction with specific protein thiolates. Again, kinetics and location are the primary determinants that provide specificity required for physiological signaling although enzymatic catalysis is not likely involved. This article is part of a Special Issue entitled "Redox Signalling in the Cardiovascular System". Copyright © 2014 Elsevier Ltd. All rights reserved.

Assessment formats in dental medicine: An overview

PubMed Central

Gerhard-Szep, Susanne; Güntsch, Arndt; Pospiech, Peter; Söhnel, Andreas; Scheutzel, Petra; Wassmann, Torsten; Zahn, Tugba

2016-01-01

Aim: At the annual meeting of German dentists in Frankfurt am Main in 2013, the Working Group for the Advancement of Dental Education (AKWLZ) initiated an interdisciplinary working group to address assessments in dental education. This paper presents an overview of the current work being done by this working group, some of whose members are also actively involved in the German Association for Medical Education's (GMA) working group for dental education. The aim is to present a summary of the current state of research on this topic for all those who participate in the design, administration and evaluation of university-specific assessments in dentistry. Method: Based on systematic literature research, the testing scenarios listed in the National Competency-based Catalogue of Learning Objectives (NKLZ) have been compiled and presented in tables according to assessment value. Results: Different assessment scenarios are described briefly in table form addressing validity (V), reliability (R), acceptance (A), cost (C), feasibility (F), and the influence on teaching and learning (EI) as presented in the current literature. Infoboxes were deliberately chosen to allow readers quick access to the information and to facilitate comparisons between the various assessment formats. Following each description is a list summarizing the uses in dental and medical education. Conclusion: This overview provides a summary of competency-based testing formats. It is meant to have a formative effect on dental and medical schools and provide support for developing workplace-based strategies in dental education for learning, teaching and testing in the future. PMID:27579365

An Overview of Three PCDC Projects.

ERIC Educational Resources Information Center

Horbaly, Marilyn; And Others

This report provides in matrix form a comprehensive overview of three Parent Child Development Centers (PCDC) projects located in Birmingham, Houston, and New Orleans. The report is divided into five sections. In Section I, the introduction, a brief description is given of the study's purpose. Section II provides demographic data from each of the…

An overview of tested and analyzed NTP concepts

NASA Technical Reports Server (NTRS)

Walton, James T.

1991-01-01

If we buy into the goals of the Space Exploration Initiative (SEI) and accept that they are worthy of the hefty investment of our tax dollars, then we must begin to evaluate the technologies which enable their attainment. The main driving technology is the propulsion systems; for interplanetary missions, the safest and most affordable is a Nuclear Thermal Propulsion (NTP) system. An overview is presented of the NTP systems which received detailed conceptual design and, for several, testing.

European Design Types for 21st Century Schools: An Overview

ERIC Educational Resources Information Center

Rigolon, Alessandro

2010-01-01

This article presents a critical overview of European school building design types, based on an analysis of morphologies and spatial layouts. The different design types are evaluated in function of specific didactic and social needs. (Contains 1 figure, 18 footnotes, a bibliography and 2 online resources.)

An Overview of the StarLight Mission

NASA Technical Reports Server (NTRS)

Lay, Oliver; Blackwood, Gary; Dubovitsky, Serge; Duren, Riley

2004-01-01

An overview of the Starlight Mission is presented. Mission summary: June 2006 launch to heliocentric orbit; Nominal 6 month mission with option of additional 6 month extension; Validate autonomous formation flying system: range control to 10 cm bearing, control to 4 arcmin; Demonstrate formation flying optical interferometry.The original 3 spacecraft design did not fit the budget. 2 spacecraft concept demonstrates all key areas of formation flying interferometry. Collector flown on the surface of a virtual paraboloid, with combiner at the focus. It Gives a baseline of 125 m with a fixed delay of only 14 m.

Collisions involving antiprotons and antihydrogen: an overview

NASA Astrophysics Data System (ADS)

Jonsell, S.

2018-03-01

I give an overview of experimental and theoretical results for antiproton and antihydrogen scattering with atoms and molecules (in particular H, He). At low energies (>1 keV) there are practically no experimental data available. Instead I compare the results from different theoretical calculations, of various degrees of sophistication. At energies up to a few tens of eV, I focus on simple approximations that give reasonably accurate results, as these allow quick estimates of collision rates without embarking on a research project. This article is part of the Theo Murphy meeting issue `Antiproton physics in the ELENA era'.

Complementary therapies for depression: an overview.

PubMed

Ernst, E; Rand, J I; Stevinson, C

1998-11-01

Depression is one of the most common reasons for using complementary and alternative therapies. The aim of this article is to provide an overview of the evidence available on the treatment of depression with complementary therapies. Systematic literature searches were performed using several databases, reference list searching, and inquiry to colleagues. Data extraction followed a predefined protocol. The amount of rigorous scientific data to support the efficacy of complementary therapies in the treatment of depression is extremely limited. The areas with the most evidence for beneficial effects are exercise, herbal therapy (Hypericum perforatum), and, to a lesser extent, acupuncture and relaxation therapies. There is a need for further research involving randomized controlled trials into the efficacy of complementary and alternative therapies in the treatment of depression.

Digital Noise Reduction: An Overview

PubMed Central

Bentler, Ruth; Chiou, Li-Kuei

2006-01-01

Digital noise reduction schemes are being used in most hearing aids currently marketed. Unlike the earlier analog schemes, these manufacturer-specific algorithms are developed to acoustically analyze the incoming signal and alter the gain/output characteristics according to their predetermined rules. Although most are modulation-based schemes (ie, differentiating speech from noise based on temporal characteristics), spectral subtraction techniques are being applied as well. The purpose of this article is to overview these schemes in terms of their differences and similarities. PMID:16959731

An overview of city analytics

PubMed Central

Higham, Desmond J.; Batty, Michael; Bettencourt, Luís M. A.; Greetham, Danica Vukadinović; Grindrod, Peter

2017-01-01

We introduce the 14 articles in the Royal Society Open Science themed issue on City Analytics. To provide a high-level, strategic, overview, we summarize the topics addressed and the analytical tools deployed. We then give a more detailed account of the individual contributions. Our overall aims are (i) to highlight exciting advances in this emerging, interdisciplinary field, (ii) to encourage further activity and (iii) to emphasize the variety of new, public-domain, datasets that are available to researchers. PMID:28386454

Crew Module Overview

NASA Technical Reports Server (NTRS)

Redifer, Matthew E.

2011-01-01

The presentation presents an overview of the Crew Module development for the Pad Abort 1 flight test. The presentation describes the integration activity from the initial delivery of the primary structure through the installation of vehicle subsystems, then to flight test. A brief overview of flight test results is given.

[Integrating the healthcare enterprise: an overview].

PubMed

Yao, Wei-hua; Zhu, Xu-yang; Duan, Ni

2003-12-01

Integrating the healthcare enterprise (IHE) is a developing general norm in medical informatics especially in the field of radiology, which is independent of the manufacturers and has been accepted by a number of manufacturers and systems. In this paper, the authors provide a brief overview of IHE with the integration profiles of IHE technical framework being particularly elaborated.

The Atacama Compact Array: An Overview

NASA Astrophysics Data System (ADS)

Iguchi, S.; Wilson, T. L.

2010-01-01

When completed, ALMA will comprise a 12-meter diameter antennas array (12-m Array) of a minimum of fifty antennas, and the ACA (Atacama Compact Array), composed of four 12-meter diameter antennas and twelve 7-meter diameter antennas. Out of the fifty antennas of the 12-m Array, one-half are provided by the North American partners of ALMA, the other half by the European partners. The sixteen antennas that will comprise the ACA are provided by the East Asian Partners of ALMA. In the last issue of the ALMA Science Newsletter, we outlined the testing of the prototype ALMA 12-meter diameter antennas and the procurement process for these antennas. In that article, only a short account was given of the antennas for the Atacama Compact Array (ACA). In the following we give an overview of the ACA, starting with an introduction to imaging using interferometers.

Androgens in health and disease: An overview

PubMed Central

Jordan, Cynthia L.; DonCarlos, Lydia

2009-01-01

This special issue of Hormones and Behavior, “Androgens in health and disease: new insights into roles and mechanisms of action,” is prompted by a number of relatively recent findings that androgens affect brain morphology and function in ways not previously or widely appreciated. Moreover, recent results also make it clear that androgens utilize a variety of signaling molecules to exert their effects on the brain, which may or may not depend on the classic nuclear androgen receptor (AR). The papers in this issue underscore these two points. This overview is not intended as a comprehensive review of androgen action on the nervous system, since the papers in this issue serve that purpose, but rather to frame the basic issues and themes that tie these papers together. The sum effect of the stories told in this issue encourages us to broaden and refocus our view of androgen action on brain and behavior—to recognize that androgens affect many aspects of brain structure and function throughout the lifespan, from shaping its sexual phenotype to influencing its propensity for disease and repair, and that at least some of these actions are exerted via non-classical modes of action that in many cases were first identified in non-neural tissue or cells. PMID:18407273

An Overview of Climatic Elements

NASA Technical Reports Server (NTRS)

Crutcher, H. L.; Johnson, D. L.

2007-01-01

This Technical Publication (TP) addresses some climatic elements with emphasis on atmospheric composition, including gas radiative characteristics. Solar radiation is discussed with considerable information on the mathematical and statistical formulae. On a worldwide basis, temperature and precipitation for the globe are discussed along with interaction in drought. Also included is the simultaneous interaction with winds, humidity, and solar radiation. Volcanology gets minimum treatment. The oceans and seas are treated in chart form along with the interrelationship of oceanic currents and El Nino and La Nina, and ENSO phenomena. Upper air circulations are discussed. Various cloud formations up to 85-95 km altitude are described. Information on tornadoes and hurricanes is also included. One section is devoted to the climate physical-chemical elements. A short discussion is given on the importance for the quality of data and/or information in descriptions of the climate. This TP presents only an overview or survey of these and other various climatic elements.

International Collaboration in Higher Education: An Overview of Critical Issues.

ERIC Educational Resources Information Center

Edelson, Paul Jay

This paper provides an overview of the challenges that impede success in collaboration among U.S. institutions of higher education and foreign institutions. There are problems in many areas, including administrative aspects, regulatory environment, the fiscal situation, and cultural and political factors. In crafting a response strategy, some…

The World-Wide Web and Mosaic: An Overview for Librarians.

ERIC Educational Resources Information Center

Morgan, Eric Lease

1994-01-01

Provides an overview of the Internet's World-Wide Web (Web), a hypertext system. Highlights include the client/server model; Uniform Resource Locator; examples of software; Web servers versus Gopher servers; HyperText Markup Language (HTML); converting files; Common Gateway Interface; organizing Web information; and the role of librarians in…

Allostery: An Overview of Its History, Concepts, Methods, and Applications.

PubMed

Liu, Jin; Nussinov, Ruth

2016-06-01

The concept of allostery has evolved in the past century. In this Editorial, we briefly overview the history of allostery, from the pre-allostery nomenclature era starting with the Bohr effect (1904) to the birth of allostery by Monod and Jacob (1961). We describe the evolution of the allostery concept, from a conformational change in a two-state model (1965, 1966) to dynamic allostery in the ensemble model (1999); from multi-subunit (1965) proteins to all proteins (2004). We highlight the current available methods to study allostery and their applications in studies of conformational mechanisms, disease, and allosteric drug discovery. We outline the challenges and future directions that we foresee. Altogether, this Editorial narrates the history of this fundamental concept in the life sciences, its significance, methodologies to detect and predict it, and its application in a broad range of living systems.

First aid in the dental practice: an overview.

PubMed

Jevon, P

2016-06-24

First aid encompasses a wide range of scenarios ranging from simple reassurance following a minor mishap to dealing with a life-threatening emergency. Dentists may need to provide first aid in their dental practice to a patient, relative or member of staff. This article provides an overview to first aid in the dental practice, including priorities, responsibilities when providing first aid, assessment of the environment and the casualty (primary survey &secondary survey). The new A3 'First Aid in the Workplace' poster is now available and is included as an insert in this issue (BDJ Vol. 220, Issue 12).

An overview of recent advances in system identification

NASA Technical Reports Server (NTRS)

Juang, Jer-Nan

1994-01-01

This paper presents an overview of the recent advances in system identification for modal testing and control of large flexible structures. Several techniques are discussed including the Observer/Kalman Filter Identification, the Observer/Controller Identification, and the State-Space System Identification in the Frequency Domain. The System/Observer/Controller Toolbox developed at NASA Langley Research Center is used to show the applications of these techniques to real aerospace structures such as the Hubble spacecraft telescope and the active flexible aircraft wing.

Overview of an Advanced Hypersonic Structural Concept Test Program

NASA Technical Reports Server (NTRS)

Stephens, Craig A.; Hudson, Larry D.; Piazza, Anthony

2007-01-01

This viewgraph presentation provides an overview of hypersonics M&S advanced structural concepts development and experimental methods. The discussion on concepts development includes the background, task objectives, test plan, and current status of the C/SiC Ruddervator Subcomponent Test Article (RSTA). The discussion of experimental methods examines instrumentation needs, sensors of interest, and examples of ongoing efforts in the development of extreme environment sensors.

An overview of the neuron ring model

NASA Technical Reports Server (NTRS)

Taber, Rod

1991-01-01

The Neuron Ring model employs an avalanche structure with two important distinctions at the neuron level. Each neuron has two memory latches; one traps maximum neuronal activation during pattern presentation, and the other records the time of latch content change. The latches filter short term memory. In the process, they preserve length 1 snapshots of activation theory history. The model finds utility in pattern classification. Its synaptic weights are first conditioned with sample spectra. The model then receives a test or unknown signal. The objective is to identify the sample closest to the test signal. Class decision follows complete presentation of the test data. The decision maker relies exclusively on the latch contents. Presented here is an overview of the Neuron Ring at the seminar level.

An Overview of Discourse Analysis and Its Usefulness in TESOL.

ERIC Educational Resources Information Center

Milne, Geraldine Veronica

This paper provides an overview of discourse analysis from a linguistic point of view, discussing why it is relevant to Teaching English to Speakers of Other Languages (TESOL). It focuses on the following: discourse and discourse analysis; discourse analysis and TESOL; approaches to discourse analysis; systemic functional linguistics; theme and…

An Overview of Promising Grades of Tool Materials Based on the Analysis of their Physical-Mechanical Characteristics

NASA Astrophysics Data System (ADS)

Kudryashov, E. A.; Smirnov, I. M.; Grishin, D. V.; Khizhnyak, N. A.

2018-06-01

The work is aimed at selecting a promising grade of a tool material, whose physical-mechanical characteristics would allow using it for processing the surfaces of discontinuous parts in the presence of shock loads. An analysis of the physical-mechanical characteristics of most common tool materials is performed and the data on a possible provision of the metal-working processes with promising composite grades are presented.

Overview of magnetic suspension research at Langley Research Center

NASA Technical Reports Server (NTRS)

Groom, Nelson J.

1992-01-01

An overview of research in small- and large-gap magnetic suspension systems at LaRC is presented. The overview is limited to systems which have been built as laboratory models or engineering models. Small-gap systems applications include the Annular Momentum Control Device (AMCD), which is a momentum storage device for the stabilization and control of spacecraft, and the Annular Suspension and Pointing System (ASPS), which is a general purpose pointing mount designed to provide orientation, mechanical isolation, and fine pointing space experiments. These devices are described and control and linearization approaches for the magnetic suspension systems for these devices are discussed. Large-gap systems applications at LaRC have been almost exclusively wind tunnel magnetic suspension systems. A brief description of these efforts is also presented.

An Overview of NASA Engine Ice-Crystal Icing Research

NASA Technical Reports Server (NTRS)

Addy, Harold E., Jr.; Veres, Joseph P.

2011-01-01

Ice accretions that have formed inside gas turbine engines as a result of flight in clouds of high concentrations of ice crystals in the atmosphere have recently been identified as an aviation safety hazard. NASA s Aviation Safety Program (AvSP) has made plans to conduct research in this area to address the hazard. This paper gives an overview of NASA s engine ice-crystal icing research project plans. Included are the rationale, approach, and details of various aspects of NASA s research.

An Overview of Public Access Computer Software Management Tools for Libraries

ERIC Educational Resources Information Center

Wayne, Richard

2004-01-01

An IT decision maker gives an overview of public access PC software that's useful in controlling session length and scheduling, Internet access, print output, security, and the latest headaches: spyware and adware. In this article, the author describes a representative sample of software tools in several important categories such as setup…

Radical oxidative cyclization of spiroacetals to bis-spiroacetals: an overview.

PubMed

Brimble, Margaret A

2004-05-31

The use of iodobenzene diacetate and iodine under photolytic conditions provides and efficient method for the oxidative cyclization of spiroacetals bearing an hydroxyalkyl side chain to bis-spiroacetals. An overview is provided of the use of this reaction for the synthesis of several bis-spiroacetal containing natural products such as the polyether antibiotics salinomycin and CP44,161 and the shellfish toxins, the spirolides.

Engineering mechanical microenvironment of macrophage and its biomedical applications.

PubMed

Li, Jing; Li, Yuhui; Gao, Bin; Qin, Chuanguang; He, Yining; Xu, Feng; Yang, Hui; Lin, Min

2018-03-01

Macrophages are the most plastic cells in the hematopoietic system and can be widely found in almost all tissues. Recently studies have shown that mechanical cues (e.g., matrix stiffness and stress/strain) can significantly affect macrophage behaviors. Although existing reviews on the physical and mechanical cues that regulate the macrophage's phenotype are available, engineering mechanical microenvironment of macrophages in vitro as well as a comprehensive overview and prospects for their biomedical applications (e.g., tissue engineering and immunotherapy) has yet to be summarized. Thus, this review provides an overview on the existing methods for engineering mechanical microenvironment of macrophages in vitro and then a section on their biomedical applications and further perspectives are presented.

Hippocampus in health and disease: An overview

PubMed Central

Anand, Kuljeet Singh; Dhikav, Vikas

2012-01-01

Hippocampus is a complex brain structure embedded deep into temporal lobe. It has a major role in learning and memory. It is a plastic and vulnerable structure that gets damaged by a variety of stimuli. Studies have shown that it also gets affected in a variety of neurological and psychiatric disorders. In last decade or so, lot has been learnt about conditions that affect hippocampus and produce changes ranging from molecules to morphology. Progresses in radiological delineation, electrophysiology, and histochemical characterization have made it possible to study this archicerebral structure in greater detail. Present paper attempts to give an overview of hippocampus, both in health and diseases. PMID:23349586

An Overview of Low-Emission Combustion Research

NASA Technical Reports Server (NTRS)

DelRosario, Ruben

2014-01-01

An overview of research efforts at NASA Glenn Research Center (GRC) in low-emission combustion technology that have made a significant impact on the Nitrogen Oxides (NOx) emission reduction in aircraft propulsion will be presented. The technology advancements and their impact on aircraft emissions will be discussed in the context of NASAs Aeronautics Research Mission Directorate (ARMD) high-level goals in fuel burn, noise and emission reductions. The highlights of the research presented will show how the past and current efforts have laid the foundation for the engines that are flying today as well as how the continued technology advancements will significantly influence the next generation of aviation propulsion system designs.

THEORY IN RELIGION AND AGING: AN OVERVIEW

PubMed Central

Levin, Jeff; Chatters, Linda M.; Taylor, Robert Joseph

2011-01-01

This paper provides an overview of theory in religion, aging, and health. It offers both a primer on theory and a roadmap for researchers. Four “tenses” of theory are described—distinct ways that theory comes into play in this field: grand theory, mid-range theory, use of theoretical models, and positing of constructs which mediate or moderate putative religious effects. Examples are given of both explicit and implicit uses of theory. Sources of theory for this field are then identified, emphasizing perspectives of sociologists and psychologists, and discussion is given to limitations of theory. Finally, reflections are offered as to why theory matters. PMID:20087662

An Overview of Landing Gear Dynamics

NASA Technical Reports Server (NTRS)

Pritchard, Jocelyn I.

1999-01-01

One of the problems facing the aircraft community is landing gear dynamics, especially shimmy and brake-induced vibration. Shimmy and brake-induced vibrations can lead to accidents due to excessive wear and shortened life of gear parts and contribute to pilot and passenger discomfort. To increase understanding of these problems, a literature survey was performed. The major focus is on work from the last ten years. Some older publications are included to understand the longevity of the problem and the background from earlier researchers. The literature survey includes analyses, testing, modeling, and simulation of aircraft landing gear; and experimental validation and characterization of shimmy and brake-induced vibration of aircraft landing gear. The paper presents an overview of the problem, background information, and a history of landing gear dynamics problems and solutions. Based on the survey an assessment and recommendations of the most critically needed enhancements to the state of the art will be presented. The status of Langley work contributing to this activity will be given.

An overview of tumorous diseases of turkeys

USDA-ARS?s Scientific Manuscript database

This overview is primarily aimed at addressing various aspects of virus-induced tumorous diseases of turkeys including review of current methods for diagnosis and control of these diseases of turkeys. Virus-induced tumorous diseases of turkeys are caused primarily by retroviruses, namely reticuloend...

An Overview of Innovative Strategies for Fracture Mechanics at NASA Langley Research Center

NASA Technical Reports Server (NTRS)

Ransom, Jonathan B.; Glaessgen, Edward H.; Ratcliffe, James G.

2010-01-01

Engineering fracture mechanics has played a vital role in the development and certification of virtually every aerospace vehicle that has been developed since the mid-20th century. NASA Langley Research Center s Durability, Damage Tolerance and Reliability Branch has contributed to the development and implementation of many fracture mechanics methods aimed at predicting and characterizing damage in both metallic and composite materials. This paper presents a selection of computational, analytical and experimental strategies that have been developed by the branch for assessing damage growth under monotonic and cyclic loading and for characterizing the damage tolerance of aerospace structures

Titanium dioxide in fuel cell technology: An overview

NASA Astrophysics Data System (ADS)

Abdullah, N.; Kamarudin, S. K.

2015-03-01

Fuel cell technology is one of the alternative energy sources for the next generation. Although this technology has proven to be one of the main methods for producing new energy sources, fuel cell technology still has some problems that hinder fuel cell commercialization. Recently, new ideas on titanium dioxide are introduced as potential solution in several applications in fuel cell technology. Thus, this article presents an overview on the applications of titanium dioxide and highlights the unique properties and benefits of titanium dioxide in fuel cell technology.

Bioimpedance imaging: an overview of potential clinical applications.

PubMed

Bayford, Richard; Tizzard, Andrew

2012-10-21

Electrical Impedance Tomography (EIT) is an imaging technique based on multiple bio impedance measurements to produce a map (image) of impedance or changes in impedance across a region. Its origins lay in geophysics where it is still used to today. This review highlights potential clinical applications of EIT. Beginning with a brief overview of the underlying principles behind the modality, it describes the background research leading towards the development of the application of EIT for monitoring pulmonary function, detecting and localising tumours and monitoring brain function.

Congressional Nominations to U.S. Service Academies: An Overview and Resources for Outreach and Management

DTIC Science & Technology

2016-04-21

Congressional Nominations to U.S. Service Academies: An Overview and Resources for Outreach and Management R. Eric Petersen Specialist in...www.crs.gov RL33213 Congressional Nominations to U.S. Service Academies: An Overview Congressional Research Service Summary Members of Congress are...authorized by law to nominate candidates for appointment to four U.S. service academies. These schools are the U.S. Military Academy, the U.S. Naval

Deployment Mechanism for Thermal Pointing System

NASA Technical Reports Server (NTRS)

Koski, Kraig

2014-01-01

The Deployment Mechanism for the Total and Spectral Solar Irradiance Sensor (TSIS) is responsible for bringing the Thermal Pointing System (TPS) from its stowed, launch locked position to the on-orbit deployed, operational position. The Deployment Mechanism also provides structural support for the TSIS optical bench and two-axis gimbal. An engineering model of the Deployment Mechanism has been environmentally qualified and life tested. This paper will give an overview of the TSIS mission and then describe the development, design, and testing of the Deployment Mechanism.

[E-learning and university nursing education: an overview of reviews].

PubMed

De Caro, Walter; Marucci, Anna Rita; Giordani, Mauro; Sansoni, Julita

2014-01-01

The increasing use of digital technologies and e-learning in nursing education and the health professions was also reflected in the time to many studies and reviews. The aim of this overview was to analyze education through e-learning technologies for nursing and health professional students. A comprehensive search of literature was conducted using database PubMed/MEDLINE, Ebsco/CINAHL, 2003-2013. The search strategy resulted in the inclusion, in first instance, of 9732 items. After the reduction of duplicates, applying limits and other parameters of inclusion/exclusion and, at the end, evaluation of quality through AMSTARD check list, we included in this overview, 22 reviews. The analized reviews were allowed to spread in different topic areas: study population (students and faculty), e-learning methods (blended learning Game/3D/situated learning) and evaluation (information technology, learning satisfaction comparison of e-learning with the traditional teaching methods) This overview demonstrates that e-learning in nursing academic education is a valid alternative to traditional learning. If e-learning activities are well structured and modulated, some advantages and economies are clear possible. Regard effects of e-learning on the improvement of ability, data are at the momenti limited when compared to traditional learning. Often e-learning appear as an adjunct respect traditional learning, but is necessary consider e-learning and digital tecnology as priority for the future of education of nursing students.

THE U.S. EVIRONMENTAL PROTECTION AGENCY ENVIRONMENTAL TECHNOLOGY VERIFICATION PROGRAM—AN OVERVIEW

EPA Science Inventory

This is an article about monitoring technologies in the Environmental Technolgy Verification (ETV) Program which will be published in the Journal of Occupational And Environmental Hygiene. This article gives an overview of the entire ETV program with emphasis on monitoring techn...

DOD Security Cooperation: An Overview of Authorities and Issues

DTIC Science & Technology

2016-08-23

Cooperation: An Overview of Authorities and Issues Congressional Research Service 13 DOD funds six Regional Centers for Security Studies , which...Expenses Necessary for Theater Security Cooperation.” Another Senate proposal would revamp DOD’s five regional centers for security studies (10 U.S.C...184) by eliminating two that are located in Washington, DC (the Africa Center for Strategic Studies and the Near East South Asia Center for Strategic

The JGOFS North Atlantic Bloom Experiment: An overview

NASA Technical Reports Server (NTRS)

Ducklow, Hugh W.

1992-01-01

The North Atlantic Bloom Experiment (NABE) of JGOFS presents a unique opportunity and challenge to the data management community because of the diversity and large size of biogeochemical data sets collected. NABE was a pilot study for JGOFS and has also served as a pilot study within the U.S. NODC for management and archiving of the data sets. Here I present an overview to some of the scientific results of NABE, which will be published as an Introduction to a special volume of NABE results in Deep-Sea Research later this year. An overview of NABE data management is given elsewhere in the present report. This is the first collection of papers from the Joint Global Ocean Flux Study (JGOFS). Formed as an international program in 1987, JGOFS has four principal elements: modelling and data management, multidisciplinary regional process studies, a global survey of biogeochemical properties and long-term time series observatories. In 1989-1990 JGOFS conducted a pilot process study of the spring phytoplankton bloom, the North Atlantic Bloom Experiment (NABE). JGOFS decided to conduct a large scale, internationally-coordinated pilot study in the North Atlantic because of its proximity to the founding nations of the project, the size and predictability of the bloom and its fundamental impact on ocean bio-geochemistry (Billett et al., 1983; Watson and Whitfield, 1985; Pfannkuche, 1992). In 1989, six research vessels from Canada, Germany, The Netherlands, the United Kingdom and the USA and over 200 scientists and students from more than a dozen nations participated in NABE. Some of their initial results are reported in this volume.

An Overview of a Trajectory-Based Solution for En Route and Terminal Area Self-Spacing: Sixth Revision

NASA Technical Reports Server (NTRS)

Abbott, Terence S.

2015-01-01

This paper presents an overview of the sixth revision to an algorithm specifically designed to support NASA's Airborne Precision Spacing concept. This algorithm is referred to as the Airborne Spacing for Terminal Arrival Routes version 13 (ASTAR13). This airborne self-spacing concept contains both trajectory-based and state-based mechanisms for calculating the speeds required to achieve or maintain a precise spacing interval. The trajectory-based capability allows for spacing operations prior to the aircraft being on a common path. This algorithm was also designed specifically to support a standalone, non-integrated implementation in the spacing aircraft. This current revision to the algorithm adds the state-based capability in support of evolving industry standards relating to airborne self-spacing.

An Overview of a Trajectory-Based Solution for En Route and Terminal Area Self-Spacing: Eighth Revision

NASA Technical Reports Server (NTRS)

Abbott, Terence S.; Swieringa, Kurt S.

2017-01-01

This paper presents an overview of the eighth revision to an algorithm specifically designed to support NASA's Airborne Precision Spacing concept. This paper supersedes the previous documentation and presents a modification to the algorithm referred to as the Airborne Spacing for Terminal Arrival Routes version 13 (ASTAR13). This airborne self-spacing concept contains both trajectory-based and state-based mechanisms for calculating the speeds required to achieve or maintain a precise spacing interval with another aircraft. The trajectory-based capability allows for spacing operations prior to the aircraft being on a common path. This algorithm was also designed specifically to support a standalone, non-integrated implementation in the spacing aircraft. This current revision to the algorithm supports the evolving industry standards relating to airborne self-spacing.

Youth Gangs: An Overview. Juvenile Justice Bulletin. Youth Gang Series.

ERIC Educational Resources Information Center

Howell, James C.

1998-01-01

This bulletin provides an overview of the problems that youth gangs pose. It pinpoints the differences between youth gangs and adult criminal organizations and examines the risk factors that lead to youth gang membership. Some promising strategies being used to curb youth gang involvement are reviewed. The proliferation of youth gangs since 1980…

An overview on the ecology of Triatominae (Hemiptera:Reduviidae).

PubMed

Galvão, Cleber; Justi, Silvia A

2015-11-01

Chagas disease, the American trypanosomiasis, is an important neglected tropical illness caused by the flagellate protozoan Trypanosoma cruzi (Kinetoplastida, Trypanosomatidae) and transmitted by insects of the subfamily Triatominae (Hemiptera: Reduviidae). Here we provide an overview on the current knowledge about Triatominae ecology, its association with human, T. cruzi infection and the immediate consequences of habitat fragmentation. We also discuss the geographic distribution of the species and the importance of predicting their distributions to control programs. Copyright © 2015 Elsevier B.V. All rights reserved.

An overview on the characterization and mechanical behavior of nanoporous Gold

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hodge, A M; Hayes, J R; Caro, J A

2005-09-13

In this paper we present what we believe are the most pressing issues in understanding the mechanical behavior of nanoporous foams. We have postulated that a gold foam presents the best candidate for a systematic study of nanoporous foams since it can be synthesized with a wide range of ligaments sizes and densities. We have also conducted preliminary tests that demonstrate (a) Au foams have a fracture behavior dictated by the ligament size, and (b) nanoporous Au is a high yield strength material. Thus, we have demonstrated the potential in developing nanoporous foams as a new class of high yieldmore » strength/low density materials.« less

Research Methods in School Psychology: An Overview.

ERIC Educational Resources Information Center

Keith, Timothy Z.

1988-01-01

This article introduces a mini-series on research methods in school psychology. A conceptual overview of research methods is presented, emphasizing the degree to which each method allows the inference that treatment affects outcome. Experimental and nonexperimental, psychometric, descriptive, and meta-analysis research methods are outlined. (SLD)

An overview of permeable reactive barriers for in situ sustainable groundwater remediation.

PubMed

Obiri-Nyarko, Franklin; Grajales-Mesa, S Johana; Malina, Grzegorz

2014-09-01

Permeable reactive barriers (PRBs) are one of the innovative technologies widely accepted as an alternative to the 'pump and treat' (P&T) for sustainable in situ remediation of contaminated groundwater. The concept of the technology involves the emplacement of a permeable barrier containing reactive materials across the flow path of the contaminated groundwater to intercept and treat the contaminants as the plume flows through it under the influence of the natural hydraulic gradient. Since the invention of PRBs in the early 1990s, a variety of materials has been employed to remove contaminants including heavy metals, chlorinated solvents, aromatic hydrocarbons, and pesticides. Contaminant removal is usually accomplished via processes such as adsorption, precipitation, denitrification and biodegradation. Despite wide acknowledgment, there are still unresolved issues about long term-performance of PRBs, which have somewhat affected their acceptability and full-scale implementation. The current paper presents an overview of the PRB technology, which includes the state of art, the merits and limitations, the reactive media used so far, and the mechanisms employed to transform or immobilize contaminants. The paper also looks at the design, construction and the long-term performance of PRBs. Copyright © 2014 Elsevier Ltd. All rights reserved.

The Law on Reduction In Force: An Overview and Update.

ERIC Educational Resources Information Center

Zirkel, Perry A.

This chapter provides an overview of legislation and litigation relating to reduction in force (RIF) with a focus on cases decided since 1980. State statutes continue to be the primary source of the law concerning RIF, so a table is provided for these statutes and their various provisions. These statutes include the dismissla-type, and the less…

Parts Selection for Space Systems - An Overview and Radiation Perspective

NASA Technical Reports Server (NTRS)

LaBel, Kenneth A.

2008-01-01

This viewgraph presentation describes the selection of electronic parts for aerospace systems from a space radiation perspective. The topics include: 1) The Trade Space Involved with Part Selection; 2) Understanding Risk; 3) Technical/Design Aspects; 4) Programmatic Overview; 5) Radiation Perspective; 6) Reliability Considerations; 7) An Example Ad hoc Battle; and 8) Sources of Radiation Data.

Marine pollution: an overview

NASA Astrophysics Data System (ADS)

Valentukevičienė, Marina; Brannvall, Evelina

2008-01-01

This overview of marine pollution follows the methodology as proposed below. Firstly, well-known databases (Science Direct, GeoRef, SpringerLINK, etc.) on technological research were studied. All collected references were divided into 27 sections following the key words associated with marine pollution, oil spills, alien species migration, etc. The most commercially promising research and development (R & D) activities seem to be market-oriented sections: detection of oil spills at sea, containment and recovery of floating oil at sea, detection of oil spills on land, disposal of oil and debris on land, alien species migration prevention from ballast water and underwater hull cleaning in water, NOx and SOx emissions, pollutions from ship-building and repair, and biogeochemical modelling. Great market demands for commercially patented innovations are very attractive for initiating new R & D projects.

An overview of turbulence compensation

NASA Astrophysics Data System (ADS)

Schutte, Klamer; van Eekeren, Adam W. M.; Dijk, Judith; Schwering, Piet B. W.; van Iersel, Miranda; Doelman, Niek J.

2012-09-01

In general, long range visual detection, recognition and identification are hampered by turbulence caused by atmospheric conditions. Much research has been devoted to the field of turbulence compensation. One of the main advantages of turbulence compensation is that it enables visual identification over larger distances. In many (military) scenarios this is of crucial importance. In this paper we give an overview of several software and hardware approaches to compensate for the visual artifacts caused by turbulence. These approaches are very diverse and range from the use of dedicated hardware, such as adaptive optics, to the use of software methods, such as deconvolution and lucky imaging. For each approach the pros and cons are given and it is indicated for which type of scenario this approach is useful. In more detail we describe the turbulence compensation methods TNO has developed in the last years and place them in the context of the different turbulence compensation approaches and TNO's turbulence compensation roadmap. Furthermore we look forward and indicate the upcoming challenges in the field of turbulence compensation.

Gender reassignment surgery: an overview.

PubMed

Selvaggi, Gennaro; Bellringer, James

2011-05-01

Gender reassignment (which includes psychotherapy, hormonal therapy and surgery) has been demonstrated as the most effective treatment for patients affected by gender dysphoria (or gender identity disorder), in which patients do not recognize their gender (sexual identity) as matching their genetic and sexual characteristics. Gender reassignment surgery is a series of complex surgical procedures (genital and nongenital) performed for the treatment of gender dysphoria. Genital procedures performed for gender dysphoria, such as vaginoplasty, clitorolabioplasty, penectomy and orchidectomy in male-to-female transsexuals, and penile and scrotal reconstruction in female-to-male transsexuals, are the core procedures in gender reassignment surgery. Nongenital procedures, such as breast enlargement, mastectomy, facial feminization surgery, voice surgery, and other masculinization and feminization procedures complete the surgical treatment available. The World Professional Association for Transgender Health currently publishes and reviews guidelines and standards of care for patients affected by gender dysphoria, such as eligibility criteria for surgery. This article presents an overview of the genital and nongenital procedures available for both male-to-female and female-to-male gender reassignment.

An overview of STRUCTURE: applications, parameter settings, and supporting software

PubMed Central

Porras-Hurtado, Liliana; Ruiz, Yarimar; Santos, Carla; Phillips, Christopher; Carracedo, Ángel; Lareu, Maria V.

2013-01-01

Objectives: We present an up-to-date review of STRUCTURE software: one of the most widely used population analysis tools that allows researchers to assess patterns of genetic structure in a set of samples. STRUCTURE can identify subsets of the whole sample by detecting allele frequency differences within the data and can assign individuals to those sub-populations based on analysis of likelihoods. The review covers STRUCTURE's most commonly used ancestry and frequency models, plus an overview of the main applications of the software in human genetics including case-control association studies (CCAS), population genetics, and forensic analysis. The review is accompanied by supplementary material providing a step-by-step guide to running STRUCTURE. Methods: With reference to a worked example, we explore the effects of changing the principal analysis parameters on STRUCTURE results when analyzing a uniform set of human genetic data. Use of the supporting software: CLUMPP and distruct is detailed and we provide an overview and worked example of STRAT software, applicable to CCAS. Conclusion: The guide offers a simplified view of how STRUCTURE, CLUMPP, distruct, and STRAT can be applied to provide researchers with an informed choice of parameter settings and supporting software when analyzing their own genetic data. PMID:23755071

Potential Environmental Impacts of Army Laser Operations: An Overview

DTIC Science & Technology

1983-06-01

Cecilia Doughty for her professional and timely editorial assistance and to Lisa North for her exemplary...8217"- •- .. ... . . ... .. ........ .. ....... .. . ... ° • ... .. ... .., ... . . .. ... .. .. ... .......... ... .. ... ..,. j .. ... .. . .. ... ... f ... ... ..... . ........ . .,C ... , SI,,I POTENTIAL ENVIRONMENTAL IMPACTS OF ARMY LASER OPERATIONS AN OVERVIEW 1. INTRO...Sciences Laboratory, White Sands Missile Range, New Mexico 88002. 10 -~~ - Iz2 L 0 *U 4 v *; LL -00 cc . J 0~ Li FI. !:aa al Go 1 I U.U ofc W u o -

Calculations of critical misfit and thickness: An overview

NASA Technical Reports Server (NTRS)

Vandermerwe, Jan H.; Jesser, W. A.

1988-01-01

This overview stresses the equilibrium/nonequilibrium nature of the physical properties, as well as the basic properties of the models, used to calculate critical misfit and critical thickness in epitaxy.

Mechanical Components Branch Test Facilities and Capabilities

NASA Technical Reports Server (NTRS)

Oswald, Fred B.

2004-01-01

The Mechanical Components Branch at NASA Glenn Research Center formulates, conducts, and manages research focused on propulsion systems for both present and advanced aeronautical and space vehicles. The branch is comprised of research teams that perform basic research in three areas: mechanical drives, aerospace seals, and space mechanisms. Each team has unique facilities for testing aerospace hardware and concepts. This report presents an overview of the Mechanical Components Branch test facilities.

Air Pollution Forecasts: An Overview

PubMed Central

Bai, Lu; Wang, Jianzhou; Lu, Haiyan

2018-01-01

Air pollution is defined as a phenomenon harmful to the ecological system and the normal conditions of human existence and development when some substances in the atmosphere exceed a certain concentration. In the face of increasingly serious environmental pollution problems, scholars have conducted a significant quantity of related research, and in those studies, the forecasting of air pollution has been of paramount importance. As a precaution, the air pollution forecast is the basis for taking effective pollution control measures, and accurate forecasting of air pollution has become an important task. Extensive research indicates that the methods of air pollution forecasting can be broadly divided into three classical categories: statistical forecasting methods, artificial intelligence methods, and numerical forecasting methods. More recently, some hybrid models have been proposed, which can improve the forecast accuracy. To provide a clear perspective on air pollution forecasting, this study reviews the theory and application of those forecasting models. In addition, based on a comparison of different forecasting methods, the advantages and disadvantages of some methods of forecasting are also provided. This study aims to provide an overview of air pollution forecasting methods for easy access and reference by researchers, which will be helpful in further studies. PMID:29673227

Air Pollution Forecasts: An Overview.

PubMed

Bai, Lu; Wang, Jianzhou; Ma, Xuejiao; Lu, Haiyan

2018-04-17

Air pollution is defined as a phenomenon harmful to the ecological system and the normal conditions of human existence and development when some substances in the atmosphere exceed a certain concentration. In the face of increasingly serious environmental pollution problems, scholars have conducted a significant quantity of related research, and in those studies, the forecasting of air pollution has been of paramount importance. As a precaution, the air pollution forecast is the basis for taking effective pollution control measures, and accurate forecasting of air pollution has become an important task. Extensive research indicates that the methods of air pollution forecasting can be broadly divided into three classical categories: statistical forecasting methods, artificial intelligence methods, and numerical forecasting methods. More recently, some hybrid models have been proposed, which can improve the forecast accuracy. To provide a clear perspective on air pollution forecasting, this study reviews the theory and application of those forecasting models. In addition, based on a comparison of different forecasting methods, the advantages and disadvantages of some methods of forecasting are also provided. This study aims to provide an overview of air pollution forecasting methods for easy access and reference by researchers, which will be helpful in further studies.

Overview: Mechanism and Control of a Prosthetic Arm.

PubMed

Kulkarni, Tushar; Uddanwadiker, Rashmi

2015-09-01

Continuous growth in industrialization and lack of awareness in safety parameters the cases of amputations are growing. The search of safer, simpler and automated prosthetic arms for managing upper limbs is expected. Continuous efforts have been made to design and develop prosthetic arms ranging from simple harness actuated to automated mechanisms with various control options. However due the cost constraints, the automated prosthetic arms are still out of the reach of needy people. Recent data have shown that there is a wide scope to develop a low cost and light weight upper limb prosthesis. This review summarizes the various designs methodologies, mechanisms and control system developed by the researchers and the advances therein. Educating the patient to develop acceptability to prosthesis and using the same for the most basic desired functions of human hand, post amputation care and to improve patient's independent life is equally important. In conclusion it can be interpreted that there is a wide scope in design in an adaptive mechanism for opening and closing of the fingers using other methods of path and position synthesis. Simple mechanisms and less parts may optimize the cost factor. Reduction in the weight of the prosthesis may be achieved using polymers used for engineering applications. Control system will remain never ending challenge for the researchers, but it is essential to maintain the simplicity from the patients perspective.

Robotics Competitions: An Overview of First© Events and VEX© Competitions

ERIC Educational Resources Information Center

Habib, Maria A.

2012-01-01

Robotics competitions generate excitement and raise the profile of a robotics program. This article provides an overview of robotics competitions, concentrating on those sponsored by FIRST (For Inspiration and Recognition of Science and Technology) and RECF (Robotics Education and Competition Foundation). FIRST® LEGO® League and VEX® robotics…

An Overview of Software for Conducting Dimensionality Assessment in Multidimensional Models

ERIC Educational Resources Information Center

Svetina, Dubravka; Levy, Roy

2012-01-01

An overview of popular software packages for conducting dimensionality assessment in multidimensional models is presented. Specifically, five popular software packages are described in terms of their capabilities to conduct dimensionality assessment with respect to the nature of analysis (exploratory or confirmatory), types of data (dichotomous,…

School Finance Equalization Management System: An Overview.

ERIC Educational Resources Information Center

Educational Testing Service, Princeton, NJ. Education Policy Research Institute.

This overview acquaints prospective users with the School Finance Equalization Management System (SFEMS), a computer-based system designed to answer questions about state aid distribution. SFEMS can determine such things as the current pattern of aid distribution, the current pattern of tax effort, or the effect of alternative expenditure and…

Poland: An energy and environmental overview

DOE Office of Scientific and Technical Information (OSTI.GOV)

Szpunar, C.B.; Bhatti, N.; Buehring, W.A.

1990-10-01

Poland's reliance on coal as its primary source of energy imposes heavy environmental costs on its economy and population. Specifically, many of Poland's air and water pollution problems can be traced to the high energy intensity of Polish industrial production. This overview presents environment and energy information for Poland. Topics discussed include: energy resources, production and use; energy production, trade and use; environmental quality and impacts; and control strategies. 109 refs., 25 figs., 40 tabs.

The Role of Trait Emotional Intelligence in Academic Performance: Theoretical Overview and Empirical Update.

PubMed

Perera, Harsha N

2016-01-01

Considerable debate still exists among scholars over the role of trait emotional intelligence (TEI) in academic performance. The dominant theoretical position is that TEI should be orthogonal or only weakly related to achievement; yet, there are strong theoretical reasons to believe that TEI plays a key role in performance. The purpose of the current article is to provide (a) an overview of the possible theoretical mechanisms linking TEI with achievement and (b) an update on empirical research examining this relationship. To elucidate these theoretical mechanisms, the overview draws on multiple theories of emotion and regulation, including TEI theory, social-functional accounts of emotion, and expectancy-value and psychobiological model of emotion and regulation. Although these theoretical accounts variously emphasize different variables as focal constructs, when taken together, they provide a comprehensive picture of the possible mechanisms linking TEI with achievement. In this regard, the article redresses the problem of vaguely specified theoretical links currently hampering progress in the field. The article closes with a consideration of directions for future research.

Experimental psychiatric illness and drug abuse models: from human to animal, an overview.

PubMed

Edwards, Scott; Koob, George F

2012-01-01

Preclinical animal models have supported much of the recent rapid expansion of neuroscience research and have facilitated critical discoveries that undoubtedly benefit patients suffering from psychiatric disorders. This overview serves as an introduction for the following chapters describing both in vivo and in vitro preclinical models of psychiatric disease components and briefly describes models related to drug dependence and affective disorders. Although there are no perfect animal models of any psychiatric disorder, models do exist for many elements of each disease state or stage. In many cases, the development of certain models is essentially restricted to the human clinical laboratory domain for the purpose of maximizing validity, whereas the use of in vitro models may best represent an adjunctive, well-controlled means to model specific signaling mechanisms associated with psychiatric disease states. The data generated by preclinical models are only as valid as the model itself, and the development and refinement of animal models for human psychiatric disorders continues to be an important challenge. Collaborative relationships between basic neuroscience and clinical modeling could greatly benefit the development of new and better models, in addition to facilitating medications development.

Cardiac rehabilitation for people with heart disease: an overview of Cochrane systematic reviews.

PubMed

Anderson, L J; Taylor, R S

2014-12-15

Overviews are a new approach to summarising evidence and synthesising results from related systematic reviews. To conduct an overview of Cochrane systematic reviews to provide a contemporary review of the evidence for cardiac rehabilitation (CR), identify opportunities for merging or splitting existing Cochrane reviews, and identify current evidence gaps to inform new review titles. The Cochrane Database of Systematic Reviews was searched to identify reviews that address the objectives of this overview. Data presentation is descriptive with tabular presentations of review- and trial-level characteristics and results. The six included Cochrane systematic reviews were of high methodological quality and included 148 randomised controlled trials in 97,486 participants. Compared to usual care alone, exercise-based CR reduces hospital admissions and improves patient health related quality of life (HRQL) in low to moderate risk heart failure and coronary heart disease (CHD) patients. At 12 months or more follow-up, there was evidence of some reduction in mortality in patients with CHD. Psychological- and education-based interventions appear to have little impact on mortality or morbidity but may improve HRQL. Home- and centre-based programmes are equally effective in improving HRQL at similar costs. Selected interventions can increase the uptake of CR programmes but evidence to support interventions that improve adherence is weak. This overview confirms that exercise-based CR is effective and safe in the management of clinically stable heart failure and post-MI and PCI patients. We discuss the implications of this overview on the future direction of the Cochrane CR reviews portfolio. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Media Stereotyping and Native Response: An Historical Overview.

ERIC Educational Resources Information Center

Churchill, Ward; And Others

1978-01-01

This historical overview examines the media treatment of native peoples and includes the following: (1) the roots of modern stereotypes; (2) development and maturation, (3) contemporary responses, (4) music, and (5) other media. (RTS)

The Cooperative US/Ukrainian Experiment: An Overview

NASA Technical Reports Server (NTRS)

1997-01-01

In this session, Session FA1, the discussion is focuses on the following topics: History of the Cooperative US/Ukrainian Experiment (CUE); The Collaborative Ukrainian Experiment, Science Overview; Double Fertilization of Inquiring Minds, Teachers and Students Investigating Plants in Space for the Collaborative Ukrainian Experiment; and Mission Operations for the Collaborative Ukrainian Experiment.

An Overview of a Trajectory-Based Solution for En Route and Terminal Area Self-Spacing: Seventh Revision

NASA Technical Reports Server (NTRS)

Abbott, Terence S.

2015-01-01

This paper presents an overview of the seventh revision to an algorithm specifically designed to support NASA's Airborne Precision Spacing concept. This paper supersedes the previous documentation and presents a modification to the algorithm referred to as the Airborne Spacing for Terminal Arrival Routes version 13 (ASTAR13). This airborne self-spacing concept contains both trajectory-based and state-based mechanisms for calculating the speeds required to achieve or maintain a precise spacing interval. The trajectory-based capability allows for spacing operations prior to the aircraft being on a common path. This algorithm was also designed specifically to support a standalone, non-integrated implementation in the spacing aircraft. This current revision to the algorithm adds the state-based capability in support of evolving industry standards relating to airborne self-spacing.

An Overview of Electrodynamic Tether Performance in the Jovian System

NASA Technical Reports Server (NTRS)

Gallagher, Dennis; Johnson, Les; Bagenal, Fran; Moore, James

1998-01-01

The Jovian magnetosphere with its strong magnetic field and rapid planetary rotation present new opportunities and challenges for the use of electrodynamic tethers. An overview of the basic plasma physics properties of an electrodynamic tether moving through the Jovian magnetosphere is examined. Tether use for both propulsion and power generation are considered. Close to the planet, tether propulsive forces are found to be as high as 50 Newtons and power levels as high as 1 million Watts.

A Business-to-Business Interoperability Testbed: An Overview

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kulvatunyou, Boonserm; Ivezic, Nenad; Monica, Martin

In this paper, we describe a business-to-business (B2B) testbed co-sponsored by the Open Applications Group, Inc. (OAGI) and the National Institute of Standard and Technology (NIST) to advance enterprise e-commerce standards. We describe the business and technical objectives and initial activities within the B2B Testbed. We summarize our initial lessons learned to form the requirements that drive the next generation testbed development. We also give an overview of a promising testing framework architecture in which to drive the testbed developments. We outline the future plans for the testbed development.

An Overview of the Literature: Research in P-12 Engineering Education

ERIC Educational Resources Information Center

Mendoza Díaz, Noemi V.; Cox, Monica F.

2012-01-01

This paper presents an extensive overview of preschool to 12th grade (P-12) engineering education literature published between 2001 and 2011. Searches were conducted through education and engineering library engines and databases as well as queries in established publications in engineering education. More than 50 publications were found,…

RNA-mediated regulation in Gram-positive pathogens: an overview punctuated with examples from the group A Streptococcus

PubMed Central

Miller, Eric W.; Cao, Tram N.; Pflughoeft, Kathryn J.; Sumby, Paul

2014-01-01

RNA-based mechanisms of regulation represent a ubiquitous class of regulators that are associated with diverse processes including nutrient sensing, stress response, modulation of horizontal gene transfer, and virulence factor expression. While better studied in Gram-negative bacteria, the literature is replete with examples of the importance of RNA-mediated regulatory mechanisms to the virulence and fitness of Gram-positives. Regulatory RNAs are classified as cis-acting, e.g. riboswitches, which modulate the transcription, translation, or stability of co-transcribed RNA, or trans-acting, e.g. small regulatory RNAs, which target separate mRNAs or proteins. The group A Streptococcus (GAS, Streptococcus pyogenes) is a Gram-positive bacterial pathogen from which several regulatory RNA mechanisms have been characterized. The study of RNA-mediated regulation in GAS has uncovered novel concepts with respect to how small regulatory RNAs may positively regulate target mRNA stability, and to how CRISPR RNAs are processed from longer precursors. This review provides an overview of RNA-mediated regulation in Gram-positive bacteria, and is highlighted with specific examples from GAS research. The key roles that these systems play in regulating bacterial virulence are discussed and future perspectives outlined. PMID:25091277

An overview of 3D software visualization.

PubMed

Teyseyre, Alfredo R; Campo, Marcelo R

2009-01-01

Software visualization studies techniques and methods for graphically representing different aspects of software. Its main goal is to enhance, simplify and clarify the mental representation a software engineer has of a computer system. During many years, visualization in 2D space has been actively studied, but in the last decade, researchers have begun to explore new 3D representations for visualizing software. In this article, we present an overview of current research in the area, describing several major aspects like: visual representations, interaction issues, evaluation methods and development tools. We also perform a survey of some representative tools to support different tasks, i.e., software maintenance and comprehension, requirements validation and algorithm animation for educational purposes, among others. Finally, we conclude identifying future research directions.

Research on atmospheric volcanic emissions - An overview

NASA Technical Reports Server (NTRS)

Friend, J. P.; Bandy, A. R.; Moyers, J. L.; Zoller, W. H.; Stoiber, R. E.; Torres, A. L.; Rose, W. I., Jr.; Mccormick, M. P.; Woods, D. C.

1982-01-01

Atmospheric abundances and the geochemical cycle of certain volatile compounds and elements may be largely influenced or entirely controlled by magmatic sources. However, better estimates of the magnitude and variability of volcanic emissions are required if the importance of this natural source of atmospheric constituents and the resulting effect on atmospheric chemistry are to be elucidated. The project 'Research on Atmospheric Volcanic Emissions' (RAVE) is concerned with the improvement of knowledge of both geological and chemical phenomena attending these emissions by means of comprehensive instrumentation on board a research aircraft making simultaneous measurements of plume constituents. A description is presented of the equipment and the procedures used in the RAVE field study of Mt. St. Helens' plume. An overview of the results is also provided.

Pediatric feeding and swallowing rehabilitation: An overview.

PubMed

van den Engel-Hoek, Lenie; Harding, Celia; van Gerven, Marjo; Cockerill, Helen

2017-05-16

Children with neurological disabilities frequently have problems with feeding and swallowing. Such problems have a significant impact on the health and well-being of these children and their families. The primary aims in the rehabilitation of pediatric feeding and swallowing disorders are focused on supporting growth, nutrition and hydration, the development of feeding activities, and ensuring safe swallowing with the aim of preventing choking and aspiration pneumonia. Pediatric feeding and swallowing disorders can be divided into four groups: transient, developmental, chronic or progressive.This article provides an overview of the available literature about the rehabilitation of feeding and swallowing disorders in infants and children. Principles of motor control, motor learning and neuroplasticity are discussed for the four groups of children with feeding and swallowing disorders.

An overview of thermionic power conversion technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, Morgan C.

1996-12-01

Thermionic energy conversion is one of the many concepts which make up the direct power conversion technologies. Specifically, thermionics is the process of changing heat directly into electricity via a material`s ability to emit electrons when heated. This thesis presents a broad overview of the engineering and physics necessary to make thermionic energy conversion (TEC) a practical reality. It begins with an introduction to the technology and the history of its development. This is followed by a discussion of the physics and engineering necessary to develop practical power systems. Special emphasis is placed on the critical issues which are stillmore » being researched. Finally, there is a discussion of the missions which this technology may fulfill.« less

Comparative and Quantitative Global Proteomics Approaches: An Overview

PubMed Central

Deracinois, Barbara; Flahaut, Christophe; Duban-Deweer, Sophie; Karamanos, Yannis

2013-01-01

Proteomics became a key tool for the study of biological systems. The comparison between two different physiological states allows unravelling the cellular and molecular mechanisms involved in a biological process. Proteomics can confirm the presence of proteins suggested by their mRNA content and provides a direct measure of the quantity present in a cell. Global and targeted proteomics strategies can be applied. Targeted proteomics strategies limit the number of features that will be monitored and then optimise the methods to obtain the highest sensitivity and throughput for a huge amount of samples. The advantage of global proteomics strategies is that no hypothesis is required, other than a measurable difference in one or more protein species between the samples. Global proteomics methods attempt to separate quantify and identify all the proteins from a given sample. This review highlights only the different techniques of separation and quantification of proteins and peptides, in view of a comparative and quantitative global proteomics analysis. The in-gel and off-gel quantification of proteins will be discussed as well as the corresponding mass spectrometry technology. The overview is focused on the widespread techniques while keeping in mind that each approach is modular and often recovers the other. PMID:28250403

Mechanical Drawing and Design.

ERIC Educational Resources Information Center

Mikulsky, Marilyn; McEnaney, Walter K.

A syllabus is provided for a comprehensive foundation course in mechanical drawing and design for grades 9, 10, 11, or 12 that is prerequisite to advanced elective courses. Introductory materials include course objectives, an overview of basic concepts, and guidelines for implementation. Brief discussions of and suggestions for the areas of design…

Cosmetic tail docking: an overview of abuse and report of an interesting case.

PubMed

Eyarefe, Oghenemega David; Oguntoye, Cecilia O

2016-02-29

This paper presents an overview of the global controversies surrounding cosmetic tail docking in puppies, some observed inconsistent practices among dog breeders and Veterinarians in West Africa, and the need for the African Veterinary Profession to take a decisive position on the cosmetic docking procedure. An interesting report of observed complications associated with cosmetic tail docking in a 3 week old male Boerboel is reported alongside the management of the ensuing complications. This paper highlights the still prevalent practice of cosmetic tail docking and seeks to enlighten clinicians towards stemming its abuse in Africa.

Child Welfare in 25 States: An Overview.

ERIC Educational Resources Information Center

National Center for Child Advocacy (DHEW/OHD), Washington, DC.

This overview presents a summary of the major findings of a 25-state survey of child welfare service delivery systems, as studied by Peat, Marwick, Mitchell & Co. in association with the Child Welfare League of America (CWLA) during the period of November 1975 through February 1976. The initial products of the survey were 25 state profiles; these…

1995 American travel survey : an overview of the survey design and methodology

DOT National Transportation Integrated Search

1995-01-01

This paper describes the methods used in the 1995 ATS. The introduction provides an overview of : the purpose and objectives of the survey followed by a description of the survey and sample designs, survey field operations, and processing of survey d...

Electrical Mechanical Maintenance. Instructor's Guide.

ERIC Educational Resources Information Center

Santa Clara County Superintendent of Schools, San Jose, CA.

This instructor's guide describes the development of a sixteen-week postsecondary course in electrical mechanical maintenance. Following introductory sections that provide background information and a course summary, the third section describes the instructional model used in the course. Section 4 presents an overview of instructional media used…

Alberta's Performance-Based Funding Mechanism.

ERIC Educational Resources Information Center

Barnetson, Bob

This paper provides an overview of the performance indicator-based accountability and funding mechanism implemented in the higher education system of Alberta, Canada. The paper defines the terms accountability and regulation, examines the use of performance indicators to demonstrate accountability, and explains how performance indicator-based…

Obsessive-compulsive disorder: an overview.

PubMed

Simpson, H B; Fallon, B A

2000-01-01

In this article, which is the first in a three-part series, the authors provide an overview of the current state of our knowledge of the phenomenology, etiology, and diagnosis of OCD. The DSM-IV criteria for OCD are presented and explicated. Disorders that are commonly comorbid with OCD (e.g., major depressive disorder, other anxiety dis-orders, Tourette's disorder) are described. The authors also discuss disorders such as body dysmorphic disorder that may be related to OCD and are often termed OCD spectrum disorders. OCD is likely to have multiple causes and the authors discuss behavioral, neuroanatomical, and neurochemical theories of OCD. Two treatments have demonstrated efficacy in OCD, cognitive-behavioral therapy and pharmacotherapy with serotonergic reuptake inhibitors, and the authors discuss how these treatments may work in light of what is known about the etiology of the disorder. The different subtypes of OCD that have been proposed are described along with their implications for treatment. The article concludes with a discussion of diagnosis that provides specific guidance for the clinician on how to assess a patient for possible OCD. The next two articles in this series will cover cognitive-behavioral and medication treatment in detail.

Writing for Journal Publication: An Overview of NNES Challenges and Strategies

ERIC Educational Resources Information Center

Fazel, Ismaeil

2013-01-01

After a brief discussion of the importance of publishing in academic journals, this paper provides an overview of studies on writing for publication of NNES (non-native English speaking) writers. Based on the related literature, different language problems facing NNES contributors, from the perspective of both NNES writers and journal editors, as…

An overview of the genetic susceptibility to alcoholism.

PubMed

Buscemi, Loredana; Turchi, Chiara

2011-01-01

Alcoholism is a multifactorial, genetically influenced disorder. It is a major health and social issue, a highly frequent disease and a cause of premature death. It is also the most expensive addictive disorder due to morbidity, mortality, societal and legal problems. Besides their involvement in alcohol-related fatalities, forensic scientists are also required to assess driving and working ability as well as permanent invalidity due to alcohol-related conditions. Greater knowledge of the genetic basis of alcoholism could improve prevention by identifying specific risk factors and mechanisms, leading to effective therapeutic strategies and eventually to personalized treatments. This overview of the recent scientific literature on the genetic basis of alcoholism summarizes the analytical strategies currently applied to the identification of candidate genes involved in alcohol-use disorders (AUDs) and discusses some genes and related phenotypes that have been shown to influence the risk of alcoholism. Alcoholism is a complex heterogeneous genetic disease. It is a quantitative disorder, in which the combined incidence of multiple genetic factors and environmental factors varies from one subject to another. Family, twin and adoption studies indicate that 50-60% of the risk of alcoholism is due to genetic factors. Risk loci for AUDs include both genes involved in alcohol pharmacokinetics and pharmacodynamics as well as genes moderating neurophysiological responses such as impulsivity, disinhibition, sensation-seeking and externalizing behaviours. Alcoholism also co-exists with other addictions and psychiatric disorders. Such co-morbidity suggests the existence of shared aetiological factors. Despite several genes that influence the risk for AUDs having been identified, the genetic bases of alcoholism remain largely unknown. Particularly the mechanism of action or the understanding of the physiology of some genes, as well as the gene-environment interactions, is still

Molecular genetics of dyslexia: an overview.

PubMed

Carrion-Castillo, Amaia; Franke, Barbara; Fisher, Simon E

2013-11-01

Dyslexia is a highly heritable learning disorder with a complex underlying genetic architecture. Over the past decade, researchers have pinpointed a number of candidate genes that may contribute to dyslexia susceptibility. Here, we provide an overview of the state of the art, describing how studies have moved from mapping potential risk loci, through identification of associated gene variants, to characterization of gene function in cellular and animal model systems. Work thus far has highlighted some intriguing mechanistic pathways, such as neuronal migration, axon guidance, and ciliary biology, but it is clear that we still have much to learn about the molecular networks that are involved. We end the review by highlighting the past, present, and future contributions of the Dutch Dyslexia Programme to studies of genetic factors. In particular, we emphasize the importance of relating genetic information to intermediate neurobiological measures, as well as the value of incorporating longitudinal and developmental data into molecular designs. Copyright © 2013 John Wiley & Sons, Ltd.

Traumatic Brain Injury. An Overview Look at Effects and Strategies for Remediation.

ERIC Educational Resources Information Center

Brongiel, Andrea

This paper provides an overview of traumatic brain injury (TBI), including incidence, definition, characteristics, assessment and identification, remediation, teacher responsibility, and parent involvement. It discusses the eligibility of students with TBI to receive appropriate and related services in school under the Individuals with…

Cell Science-02 Payload Overview

NASA Technical Reports Server (NTRS)

Mitchell, Sarah Diane

2014-01-01

The presentation provides an general overview of the Cell Science-02 science and payload operations to the NASA Payload Operations Integrated Working Group. The overview includes a description of the science objectives and specific aims, manifest status, and operations concept.

Breastfeeding and Postpartum Depression: An Overview and Methodological Recommendations for Future Research

PubMed Central

Pope, Carley J.; Mazmanian, Dwight

2016-01-01

Emerging research suggests that a relationship exists between breastfeeding and postpartum depression; however, the direction and precise nature of this relationship are not yet clear. The purpose of this paper is to provide an overview of the relationship between breastfeeding and postpartum depression as it has been examined in the empirical literature. Also, the potential mechanisms of action that have been implicated in this relationship are also explored. PubMed and PsycINFO were searched using the keywords: breastfeeding with postpartum depression, perinatal depression, postnatal depression. Results of this search showed that researchers have examined this relationship in diverse ways using diverse methodology. In particular, researchers have examined the relationships between postpartum depression and breastfeeding intention, initiation, duration, and dose. Due to a number of methodological differences among past studies we make some recommendations for future research that will better facilitate an integration of findings. Future research should (1) use standardized assessment protocols; (2) confirm diagnosis through established clinical interview when possible; (3) provide a clear operationalized definition for breastfeeding variables; (4) clearly define the postpartum period interval assessed and time frame for onset of symptoms; (5) be prospective or longitudinal in nature; and (6) take into consideration other potential risk factors identified in the empirical literature. PMID:27148457

A Review on Human Reinstatement Studies: An Overview and Methodological Challenges

ERIC Educational Resources Information Center

Haaker, Jan; Golkar, Armita; Hermans, Dirk; Lonsdorf, Tina B.

2014-01-01

In human research, studies of return of fear (ROF) phenomena, and reinstatement in particular, began only a decade ago and recently are more widely used, e.g., as outcome measures for fear/extinction memory manipulations (e.g., reconsolidation). As reinstatement research in humans is still in its infancy, providing an overview of its stability and…

Gamma-Ray Bursts: An Overview

NASA Technical Reports Server (NTRS)

Fishman, Gerald J.

1995-01-01

A history and overview of the observed properties of gamma-ray bursts are presented. The phenomenon of gamma-ray bursts is without precedent in astronomy, having no observed property that would be a direct indicator of their distance and no counterpart object in another wavelength region. Their brief, random appearance only in the gamma-ray region has made their study difficult. The observed time profiles, spectral properties, and durations of gamma-ray bursts cover a wide range. All proposed models for their origin must be considered speculative. It is humbling to think that even after 25 years since their discovery, the distance scale of gamma-ray bursts is still very much debatable.

CSBF Engineering Overview

NASA Astrophysics Data System (ADS)

Orr, Dwayne

CSBF Engineering Overview Dwayne Orr (Presenting Author) Columbia Scientific Balloon Facility, Palestine, Texas (USA) Dwayne.Orr@csbf.nasa.gov The Columbia Scientific Balloon Facility (CSBF) at Palestine, Texas provides operational and engineering support for the launch of NASA Scientific Balloons. Over the years with the support of the NASA Balloon Program Office, CSBF has developed unique flight systems with the focus of providing a highly reliable, cost effective medium for giving Scientist’s access to a near space environment. This paper will provide an overview of the CSBF flight systems with an emphasis on recent developments and plans for the future.

Polymer-based composites for aerospace: An overview of IMAST results

NASA Astrophysics Data System (ADS)

Milella, Eva; Cammarano, Aniello

2016-05-01

This paper gives an overview of technological results, achieved by IMAST, the Technological Cluster on Engineering of Polymeric Composite Materials and Structures, in the completed Research Projects in the aerospace field. In this sector, the Cluster developed different solutions: lightweight multifunctional fiber-reinforced polymer composites for aeronautic structures, advanced manufacturing processes (for the optimization of energy consumption and waste reduction) and multifunctional components (e.g., thermal, electrical, acoustic and fire resistance).

An overview of artificial intelligence and robotics. Volume 2: Robotics

NASA Technical Reports Server (NTRS)

Gevarter, W. B.

1982-01-01

This report provides an overview of the rapidly changing field of robotics. The report incorporates definitions of the various types of robots, a summary of the basic concepts, utilized in each of the many technical areas, review of the state of the art and statistics of robot manufacture and usage. Particular attention is paid to the status of robot development, the organizations involved, their activities, and their funding.

An Overview of MSHN: The Management System for Heterogeneous Networks

DTIC Science & Technology

1999-04-01

An Overview of MSHN: The Management System for Heterogeneous Networks Debra A. Hensgen†, Taylor Kidd†, David St. John§, Matthew C . Schnaidt†, Howard...ABSTRACT UU 18. NUMBER OF PAGES 15 19a. NAME OF RESPONSIBLE PERSON a. REPORT unclassified b. ABSTRACT unclassified c . THIS PAGE...Alhusaini, V. K. Prasanna, and C . S. Raghavendra, “A unified resource scheduling framework for heterogeneous computing environments,” Proc. 8th IEEE

An overview of negative hydrogen ion sources for accelerators

NASA Astrophysics Data System (ADS)

Faircloth, Dan; Lawrie, Scott

2018-02-01

An overview of high current (>1 mA) negative hydrogen ion (H-) sources that are currently used on particle accelerators. The current understanding of how H- ions are produced is summarised. Issues relating to caesium usage are explored. The different ways of expressing emittance and beam currents are clarified. Source technology naming conventions are defined and generalised descriptions of each source technology are provided. Examples of currently operating sources are outlined, with their current status and future outlook given. A comparative table is provided.

An overview of multiphase cartilage mechanical modelling and its role in understanding function and pathology.

PubMed

Klika, Václav; Gaffney, Eamonn A; Chen, Ying-Chun; Brown, Cameron P

2016-09-01

There is a long history of mathematical and computational modelling with the objective of understanding the mechanisms governing cartilage׳s remarkable mechanical performance. Nonetheless, despite sophisticated modelling development, simulations of cartilage have consistently lagged behind structural knowledge and thus the relationship between structure and function in cartilage is not fully understood. However, in the most recent generation of studies, there is an emerging confluence between our structural knowledge and the structure represented in cartilage modelling. This raises the prospect of further refinement in our understanding of cartilage function and also the initiation of an engineering-level understanding for how structural degradation and ageing relates to cartilage dysfunction and pathology, as well as informing the potential design of prospective interventions. Aimed at researchers entering the field of cartilage modelling, we thus review the basic principles of cartilage models, discussing the underlying physics and assumptions in relatively simple settings, whilst presenting the derivation of relatively parsimonious multiphase cartilage models consistent with our discussions. We proceed to consider modern developments that start aligning the structure captured in the models with observed complexities. This emphasises the challenges associated with constitutive relations, boundary conditions, parameter estimation and validation in cartilage modelling programmes. Consequently, we further detail how both experimental interrogations and modelling developments can be utilised to investigate and reduce such difficulties before summarising how cartilage modelling initiatives may improve our understanding of cartilage ageing, pathology and intervention. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

WEAVE an overview and status update

NASA Astrophysics Data System (ADS)

Bonifacio, P.; Dalton, G.; Trager, S.; Aguerri, A. L.; Carrasco, E.; Vallenari, A.; Abrams, D. C.; Middleton, K.; Sayède, F.

2016-12-01

The WHT Enhanced Area Velocity Explorer is a high multiplex, multi-object spectrograph that will equip the prime focus of the WHT 4.2m telescope. The instrument is currently in the construction phase and several components have already been procured. I will give a short overview of the instrument and of the project and its status. The French participation is done through CNRS - Institut National des Sciences de l'Univers and the technical activity is carried out, at this stage, at GEPI, Observatoire de Paris.

Interactive Simulations to Support Quantum Mechanics Instruction for Chemistry Students

ERIC Educational Resources Information Center

Kohnle, Antje; Benfield, Cory; Hahner, Georg; Paetkau, Mark

2017-01-01

The QuVis Quantum Mechanics Visualization Project provides freely available research-based interactive simulations with accompanying activities for the teaching and learning of quantum mechanics across a wide range of topics and levels. This article gives an overview of some of the simulations and describes their use in an introductory physical…

An Overview of Dental Radiology. NCHCT Monograph Series.

ERIC Educational Resources Information Center

Manny, Edward F.; And Others

This overview of dental radiology contains sections on demographics, equipment, dental radiology quality assurance, efficacy, dental radiology education curricula, professional organizations' guidelines for training and use, and state activities. In section 1 dental personnel, population of dental personnel, employment and earning prospects,…

Marine Polysaccharides in Pharmaceutical Applications: An Overview

PubMed Central

Laurienzo, Paola

2010-01-01

The enormous variety of polysaccharides that can be extracted from marine plants and animal organisms or produced by marine bacteria means that the field of marine polysaccharides is constantly evolving. Recent advances in biological techniques allow high levels of polysaccharides of interest to be produced in vitro. Biotechnology is a powerful tool to obtain polysaccharides from a variety of micro-organisms, by controlling the growth conditions in a bioreactor while tailoring the production of biologically active compounds. Following an overview of the current knowledge on marine polysaccharides, with special attention to potential pharmaceutical applications and to more recent progress on the discovering of new polysaccharides with biological appealing characteristics, this review will focus on possible strategies for chemical or physical modification aimed to tailor the final properties of interest. PMID:20948899

An Overview-NASA LeRC Structures Program

NASA Technical Reports Server (NTRS)

Zaretsky, Erwin V.

1997-01-01

The Structures and Acoustics Division of the NASA Lewis Research Center has its genesis dating back to 1943. It has been an independent Division at Lewis since 1979. Its two primary capabilities are performance and life analysis of static and dynamic systems such as those found in aircraft and spacecraft propulsion systems and experimental verification of these analyses. Research is conducted in-house, through university grants and contracts, and through cooperative programs with industry. Our work directly supports NASA's Advanced Subsonic Technology (AST), Smart Green Engine, Fast Quiet Engine, High-Temperature Materials and Processing (HiTEMP), Hybrid Hyperspeed Propulsion, Rotorcraft, High-Speed Research (HSR), and Aviation Safety Program (AvSP). A general overview is given discussing these programs and other technologies that are being developed at NASA LeRC.

The Hinode(Solar-B)Mission: An Overview

NASA Technical Reports Server (NTRS)

Kosugi, T.; Matsuzaki, K.; Sakao, T.; Shimizu, T.; Sone, Y.; Tachikawa, S.; Minesugi, K.; Ohnishi, A.; Yamada, T.; Tsuneta, S.;

Atmospheric Sciences Information Resources in the United States--An Overview for Librarians.

ERIC Educational Resources Information Center

Layman, Mary; Smith, Shirley

1993-01-01

Presents an overview of the types of information and information sources available in the field of atmospheric sciences. Included are major library collections; organizations; government programs, including air pollution control regulations; electronic databases; and networking resources. Addresses are provided for all sources, and definitions of…

Jobs, collaborations, and women leaders of the global chemistry enterprise: An overview

USDA-ARS?s Scientific Manuscript database

The global chemistry enterprise continues to be active and contributes substantially to the gross domestic products and employment in many countries. This article provides an overview of the issues of jobs, collaborations, and women leaders of the global chemistry enterprise. The availability of job...

OVERVIEW OF AN INTEGRATIVE SAMPLER FOR ...

EPA Pesticide Factsheets

Anthropogenic pollution is recognized as a global problem contributing to degradation of ecosystem quality, to loss of numerous plant and animal species, and to adverse impacts on human health. There is an increasing realization that a holistic hazard assessment of complex environmental contaminant mixtures requires data on the concentrations of hydrophilic organic contaminants as well. An approach to provide a time-weighted average (TWA) assessment is critical in understanding organism exposure to the complex mixture of pollutants present in the environment. A recently developed device, the polar organic chemical integrative sampler (POCIS), is designed to integratively sample the more polar waterborne organic chemicals. Laboratory trials and field deployments have demonstrated that the POCIS is very effective for sequestering hydrophilic chemicals such as antibiotics, hormones, other pharmaceutically derived chemicals, polar pesticides, surfactants, etc. Environmentally derived sample extracts from the integrative samplers are readily amenable for assays utilizing bio-indicator tests. An overview of the POCIS and selected environmental applications will be presented. The research focused on in the subtasks is the development and application of state-of the-art technologies to meet the needs of the public, Office of Water, and ORD in the area of Water Quality. Located In the subtasks are the various research projects being performed in support of this Task and

An Overview of the Scholarship of Teaching and Learning in Mathematics

ERIC Educational Resources Information Center

Bennett, Curtis D.; Dewar, Jacqueline M.

2012-01-01

This article provides an overview of the scholarship of teaching and learning (SoTL) in mathematics. It describes the origins of SoTL in higher education and distinguishes SoTL from good teaching, scholarly teaching, and mathematics education research. It includes a widely adopted taxonomy of SoTL questions and presents several examples of SoTL…

An Overview of the Jupiter Europa Orbiter Concept's Europa Science Phase Orbit Design

NASA Technical Reports Server (NTRS)

Lock, Robert E.; Ludwinski, Jan M.; Petropoulos, Anastassios E.; Clark, Karla B.; Pappalardo, Robert T.

2009-01-01

Jupiter Europa Orbiter (JEO), the proposed NASA element of the proposed joint NASA-ESA Europa Jupiter System Mission (EJSM), could launch in February 2020 and conceivably arrive at Jupiter in December of 2025. The concept is to perform a multi-year study of Europa and the Jupiter system, including 30 months of Jupiter system science and a comprehensive Europa orbit phase of 9 months. This paper provides an overview of the JEO concept and describes the Europa Science phase orbit design and the related science priorities, model pay-load and operations scenarios needed to conduct the Europa Science phase. This overview is for planning and discussion purposes only.

The metabolism of carbadox, olaquindox, mequindox, quinocetone and cyadox: an overview.

PubMed

Liu, Zhao-Ying; Sun, Zhi-Liang

2013-12-01

The aim of this article is to get an overview of the metabolism of quinoxaline 1,4-di-N-oxides (QdNOs) used in food animals. The derivatives of QdNOs (carbadox, olaquindox, mequindox, quinocetone, and cyadox) are the potent synthetic antimicrobial agents that are used for improving the feed efficiency and controlling dysentery in food-producing animals. Studies have demonstrated that the toxicity of QdNOs is closely associated with the production of their metabolism, especially with the production of their reduced metabolites. To the best of our knowledge, no one has systematically compiled the metabolism data of QdNOs. Therefore, the metabolism of QdNOs in animals has been discussed in the review for the first time. These drugs undergo extensive metabolism prior to excretion. N-oxide group reduction is the major metabolic pathway of QdNOs. Moreover, the N1- and N4-oxide reductions of QdNOs by different reducing mechanisms are also described. Obvious differences in metabolic pathways for QdNOs were observed owing to the differences on the side chain of these drugs. Therefore, understanding the metabolic pathways of QdNOs in animals will provide the guides for further studies of metabolism and toxicology of these drugs, and will also provide abundant information for the food safety assessment.

An overview of interstitial brachytherapy and hyperthermia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brandt, B.B.; Harney, J.

Interstitial thermoradiotherapy, an experimental cancer treatment that combines interstitial radiation implants (brachytherapy) and interstitial hyperthermia, is in the early stages of investigation. In accordance with the procedure used in a current national trial protocol, a 60-minute hyperthermia treatment is administered after catheters are placed into the tumor area while the patient is under general anesthesia. This is immediately followed by loading of radioactive Iridium-192 seeds into the catheters for a defined period of time. Once the prescribed radiation dose is delivered, the radioactive sources are removed and a second, 60-minute hyperthermia treatment is administered. Clinical trials with hyperthermia in combinationmore » with radiation have increased in recent years. Nurses caring for these patients need to become more knowledgeable about this investigational therapy. This paper provides an overview of the biologic rationale for this therapy, as well as a description of the delivery method and clinical application. Specific related nursing interventions are defined in a nursing protocol.23 references.« less

Magnetic resonance imaging of the pediatric neck: an overview.

PubMed

Shekdar, Karuna V; Mirsky, David M; Kazahaya, Ken; Bilaniuk, Larissa T

2012-08-01

Evaluation of neck lesions in the pediatric population can be a diagnostic challenge, for which magnetic resonance (MR) imaging is extremely valuable. This article provides an overview of the value and utility of MR imaging in the evaluation of pediatric neck lesions, addressing what the referring clinician requires from the radiologist. Concise descriptions and illustrations of MR imaging findings of commonly encountered pathologic entities in the pediatric neck, including abnormalities of the branchial apparatus, thyroglossal duct anomalies, and neoplastic processes, are given. An approach to establishing a differential diagnosis is provided, and critical points of information are summarized. Copyright © 2012 Elsevier Inc. All rights reserved.

Materials for Wind Turbine Blades: An Overview.

PubMed

Mishnaevsky, Leon; Branner, Kim; Petersen, Helga Nørgaard; Beauson, Justine; McGugan, Malcolm; Sørensen, Bent F

2017-11-09

A short overview of composite materials for wind turbine applications is presented here. Requirements toward the wind turbine materials, loads, as well as available materials are reviewed. Apart from the traditional composites for wind turbine blades (glass fibers/epoxy matrix composites), natural composites, hybrid and nanoengineered composites are discussed. Manufacturing technologies for wind turbine composites, as well their testing and modelling approaches are reviewed.

Materials for Wind Turbine Blades: An Overview

PubMed Central

Branner, Kim; Petersen, Helga Nørgaard; Beauson, Justine; McGugan, Malcolm; Sørensen, Bent F.

2017-01-01

A short overview of composite materials for wind turbine applications is presented here. Requirements toward the wind turbine materials, loads, as well as available materials are reviewed. Apart from the traditional composites for wind turbine blades (glass fibers/epoxy matrix composites), natural composites, hybrid and nanoengineered composites are discussed. Manufacturing technologies for wind turbine composites, as well their testing and modelling approaches are reviewed. PMID:29120396

[Artificial intelligence in psychiatry-an overview].

PubMed

Meyer-Lindenberg, A

2018-06-18

Artificial intelligence and the underlying methods of machine learning and neuronal networks (NN) have made dramatic progress in recent years and have allowed computers to reach superhuman performance in domains that used to be thought of as uniquely human. In this overview, the underlying methodological developments that made this possible are briefly delineated and then the applications to psychiatry in three domains are discussed: precision medicine and biomarkers, natural language processing and artificial intelligence-based psychotherapeutic interventions. In conclusion, some of the risks of this new technology are mentioned.

An Overview of the Genetics of Plant Response to Salt Stress: Present Status and the Way Forward.

PubMed

Kaleem, Fawad; Shabir, Ghulam; Aslam, Kashif; Rasul, Sumaira; Manzoor, Hamid; Shah, Shahid Masood; Khan, Abdul Rehman

2018-04-02

Salinity is one of the major threats faced by the modern agriculture today. It causes multidimensional effects on plants. These effects depend upon the plant growth stage, intensity, and duration of the stress. All these lead to stunted growth and reduced yield, ultimately inducing economic loss to the farming community in particular and to the country in general. The soil conditions of agricultural land are deteriorating at an alarming rate. Plants assess the stress conditions, transmit the specific stress signals, and then initiate the response against that stress. A more complete understanding of plant response mechanisms and their practical incorporation in crop improvement is an essential step towards achieving the goal of sustainable agricultural development. Literature survey shows that investigations of plant stresses response mechanism are the focus area of research for plant scientists. Although these efforts lead to reveal different plant response mechanisms against salt stress, yet many questions still need to be answered to get a clear picture of plant strategy to cope with salt stress. Moreover, these studies have indicated the presence of a complicated network of different integrated pathways. In order to work in a progressive way, a review of current knowledge is critical. Therefore, this review aims to provide an overview of our understanding of plant response to salt stress and to indicate some important yet unexplored dynamics to improve our knowledge that could ultimately lead towards crop improvement.

An overview of transcriptional regulation in response to toxicological insult.

PubMed

Jennings, Paul; Limonciel, Alice; Felice, Luca; Leonard, Martin O

2013-01-01

The completion of the human genome project and the subsequent advent of DNA microarray and high-throughput sequencing technologies have led to a renaissance in molecular toxicology. Toxicogenomic data sets, from both in vivo and in vitro studies, are growing exponentially, providing a wealth of information on regulation of stress pathways at the transcriptome level. Through such studies, we are now beginning to appreciate the diversity and complexity of biological responses to xenobiotics. In this review, we aim to consolidate and summarise the major toxicologically relevant transcription factor-governed molecular pathways. It is becoming clear that different chemical entities can cause oxidative, genotoxic and proteotoxic stress, which induce cellular responses in an effort to restore homoeostasis. Primary among the response pathways involved are NFE2L2 (Nrf2), NFE2L1 (Nrf1), p53, heat shock factor and the unfolded protein response. Additionally, more specific mechanisms exist where xenobiotics act as ligands, including the aryl hydrocarbon receptor, metal-responsive transcription factor-1 and the nuclear receptor family of transcription factors. Other pathways including the immunomodulatory transcription factors NF-κB and STAT together with the hypoxia-inducible transcription factor HIF are also implicated in cellular responses to xenobiotic exposure. A less specific but equally important aspect to cellular injury controlled by transcriptional activity is loss of tissue-specific gene expression, resulting in dedifferentiation of target cells and compromise of tissue function. Here, we review these pathways and the genes they regulate in order to provide an overview of this growing field of molecular toxicology.

Indian Solar Cities Programme: An Overview of Major Activities and Accomplishments; Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kandt, A.

This paper details the Indian Solar City Programme, provides an overview of one city's Master Plan and implementation progress, describes NREL's support of the Indian Solar City Programme, and outlines synergies and differences between the Indian and American programs including unique challenges and opportunities India is facing.

AN OVERVIEW OF ELASTOGRAPHY – AN EMERGING BRANCH OF MEDICAL IMAGING

PubMed Central

Sarvazyan, Armen; Hall, Timothy J.; Urban, Matthew W.; Fatemi, Mostafa; Aglyamov, Salavat R.; Garra, Brian S.

2011-01-01

From times immemorial manual palpation served as a source of information on the state of soft tissues and allowed detection of various diseases accompanied by changes in tissue elasticity. During the last two decades, the ancient art of palpation gained new life due to numerous emerging elasticity imaging (EI) methods. Areas of applications of EI in medical diagnostics and treatment monitoring are steadily expanding. Elasticity imaging methods are emerging as commercial applications, a true testament to the progress and importance of the field. In this paper we present a brief history and theoretical basis of EI, describe various techniques of EI and, analyze their advantages and limitations, and overview main clinical applications. We present a classification of elasticity measurement and imaging techniques based on the methods used for generating a stress in the tissue (external mechanical force, internal ultrasound radiation force, or an internal endogenous force), and measurement of the tissue response. The measurement method can be performed using differing physical principles including magnetic resonance imaging (MRI), ultrasound imaging, X-ray imaging, optical and acoustic signals. Until recently, EI was largely a research method used by a few select institutions having the special equipment needed to perform the studies. Since 2005 however, increasing numbers of mainstream manufacturers have added EI to their ultrasound systems so that today the majority of manufacturers offer some sort of Elastography or tissue stiffness imaging on their clinical systems. Now it is safe to say that some sort of elasticity imaging may be performed on virtually all types of focal and diffuse disease. Most of the new applications are still in the early stages of research, but a few are becoming common applications in clinical practice. PMID:22308105

High density plasmas and new diagnostics: An overview (invited).

PubMed

Celona, L; Gammino, S; Mascali, D

2016-02-01

One of the limiting factors for the full understanding of Electron Cyclotron Resonance Ion Sources (ECRISs) fundamental mechanisms consists of few types of diagnostic tools so far available for such compact machines. Microwave-to-plasma coupling optimisation, new methods of density overboost provided by plasma wave generation, and magnetostatic field tailoring for generating a proper electron energy distribution function, suitable for optimal ion beams formation, require diagnostic tools spanning across the entire electromagnetic spectrum from microwave interferometry to X-ray spectroscopy; these methods are going to be implemented including high resolution and spatially resolved X-ray spectroscopy made by quasi-optical methods (pin-hole cameras). The ion confinement optimisation also requires a complete control of cold electrons displacement, which can be performed by optical emission spectroscopy. Several diagnostic tools have been recently developed at INFN-LNS, including "volume-integrated" X-ray spectroscopy in low energy domain (2-30 keV, by using silicon drift detectors) or high energy regime (>30 keV, by using high purity germanium detectors). For the direct detection of the spatially resolved spectral distribution of X-rays produced by the electronic motion, a "pin-hole camera" has been developed also taking profit from previous experiences in the ECRIS field. The paper will give an overview of INFN-LNS strategy in terms of new microwave-to-plasma coupling schemes and advanced diagnostics supporting the design of new ion sources and for optimizing the performances of the existing ones, with the goal of a microwave-absorption oriented design of future machines.

The Transition of Acute Postoperative Pain to Chronic Pain: An Integrative Overview of Research on Mechanisms.

PubMed

Chapman, C Richard; Vierck, Charles J

2017-04-01

The nature of the transition from acute to chronic pain still eludes explanation, but chronic pain resulting from surgery provides a natural experiment that invites clinical epidemiological investigation and basic scientific inquiry into the mechanisms of this transition. The primary purpose of this article is to review current knowledge and hypotheses on the transition from acute to persistent postsurgical pain, summarizing literature on clinical epidemiological studies of persistent postsurgical pain development, as well as basic neurophysiological studies targeting mechanisms in the periphery, spinal cord, and brain. The second purpose of this article is to integrate theory, information, and causal reasoning in these areas. Conceptual mapping reveals 5 classes of hypotheses pertaining to pain. These propose that chronic pain results from: 1) persistent noxious signaling in the periphery; 2) enduring maladaptive neuroplastic changes at the spinal dorsal horn and/or higher central nervous system structures reflecting a multiplicity of factors, including peripherally released neurotrophic factors and interactions between neurons and microglia; 3) compromised inhibitory modulation of noxious signaling in medullary-spinal pathways; 4) descending facilitatory modulation; and 5) maladaptive brain remodeling in function, structure, and connectivity. The third purpose of this article is to identify barriers to progress and review opportunities for advancing the field. This review reveals a need for a concerted, strategic effort toward integrating clinical epidemiology, basic science research, and current theory about pain mechanisms to hasten progress toward understanding, managing, and preventing persistent postsurgical pain. The development of chronic pain after surgery is a major clinical problem that provides an opportunity to study the transition from acute to chronic pain at epidemiologic and basic science levels. Strategic, coordinated, multidisciplinary research

OVERVIEW.

ERIC Educational Resources Information Center

ROSENBERG, SHELDON

THIS OVERVIEW CHAPTER INTRODUCES THE FORTHCOMING "DEVELOPMENTS IN APPLIED PSYCHOLINGUISTICS RESEARCH," S. ROSENBERG AND J.H. KOPLIN, EDITORS, WHICH WILL BE PUBLISHED IN 1968 BY MACMILLAN COMPANY. IT WAS DESIGNED TO SERVE AN INTEGRATIVE FUNCTION--TO IDENTIFY SOME OF THE MAJOR IDEAS AND CONCERNS OF THE CONTRIBUTORS, TO IDENTIFY SOME OF THEIR…

Constellation Architecture Team-Lunar Scenario 12.0 Habitation Overview

NASA Technical Reports Server (NTRS)

Kennedy, Kriss J.; Toups, Larry D.; Rudisill, Marianne

2010-01-01

This paper will describe an overview of the Constellation Architecture Team Lunar Scenario 12.0 (LS-12) surface habitation approach and concept performed during the study definition. The Lunar Scenario 12 architecture study focused on two primary habitation approaches: a horizontally-oriented habitation module (LS-12.0) and a vertically-oriented habitation module (LS-12.1). This paper will provide an overview of the 12.0 lunar surface campaign, the associated outpost architecture, habitation functionality, concept description, system integration strategy, mass and power resource estimates. The Scenario 12 architecture resulted from combining three previous scenario attributes from Scenario 4 "Optimized Exploration", Scenario 5 "Fission Surface Power System" and Scenario 8 "Initial Extensive Mobility" into Scenario 12 along with an added emphasis on defining the excursion ConOps while the crew is away from the outpost location. This paper will describe an overview of the CxAT-Lunar Scenario 12.0 habitation concepts and their functionality. The Crew Operations area includes basic crew accommodations such as sleeping, eating, hygiene and stowage. The EVA Operations area includes additional EVA capability beyond the suitlock function such as suit maintenance, spares stowage, and suit stowage. The Logistics Operations area includes the enhanced accommodations for 180 days such as enhanced life support systems hardware, consumable stowage, spares stowage, interconnection to the other habitation elements, a common interface mechanism for future growth, and mating to a pressurized rover or Pressurized Logistics Module (PLM). The Mission & Science Operations area includes enhanced outpost autonomy such as an IVA glove box, life support, medical operations, and exercise equipment.

Alternative microbial methods: An overview and selection criteria.

PubMed

Jasson, Vicky; Jacxsens, Liesbeth; Luning, Pieternel; Rajkovic, Andreja; Uyttendaele, Mieke

2010-09-01

This study provides an overview and criteria for the selection of a method, other than the reference method, for microbial analysis of foods. In a first part an overview of the general characteristics of rapid methods available, both for enumeration and detection, is given with reference to relevant bibliography. Perspectives on future development and the potential of the rapid method for routine application in food diagnostics are discussed. As various alternative "rapid" methods in different formats are available on the market, it can be very difficult for a food business operator or for a control authority to select the most appropriate method which fits its purpose. Validation of a method by a third party, according to international accepted protocol based upon ISO 16140, may increase the confidence in the performance of a method. A list of at the moment validated methods for enumeration of both utility indicators (aerobic plate count) and hygiene indicators (Enterobacteriaceae, Escherichia coli, coagulase positive Staphylococcus) as well as for detection of the four major pathogens (Salmonella spp., Listeria monocytogenes, E. coli O157 and Campylobacter spp.) is included with reference to relevant websites to check for updates. In a second part of this study, selection criteria are introduced to underpin the choice of the appropriate method(s) for a defined application. The selection criteria link the definition of the context in which the user of the method functions - and thus the prospective use of the microbial test results - with the technical information on the method and its operational requirements and sustainability. The selection criteria can help the end user of the method to obtain a systematic insight into all relevant factors to be taken into account for selection of a method for microbial analysis. Copyright 2010 Elsevier Ltd. All rights reserved.

An Overview of Modeling Middle Atmospheric Odd Nitrogen

NASA Technical Reports Server (NTRS)

Jackman, Charles H.; Kawa, S. Randolph; Einaudi, Franco (Technical Monitor)

2001-01-01

Odd nitrogen (N, NO, NO2, NO3, N2O5, HNO3, HO2NO2, ClONO2, and BrONO2) constituents are important components in the control of middle atmospheric ozone. Several processes lead to the production of odd nitrogen (NO(sub y)) in the middle atmosphere (stratosphere and mesosphere) including the oxidation of nitrous oxide (N2O), lightning, downflux from the thermosphere, and energetic charged particles (e.g., galactic cosmic rays, solar proton events, and energetic electron precipitation). The dominant production mechanism of NO(sub y) in the stratosphere is N2O oxidation, although other processes contribute. Mesospheric NO(sub y) is influenced by N2O oxidation, downflux from the thermosphere, and energetic charged particles. NO(sub y) is destroyed in the middle atmosphere primarily via two processes: 1) dissociation of NO to form N and O followed by N + NO yielding N2 + O to reform even nitrogen; and 2) transport to the troposphere where HNO3 can be rapidly scavenged in water droplets and rained out of the atmosphere. There are fairly significant differences among global models that predict NO(sub y). NO(sub y) has a fairly long lifetime in the stratosphere (months to years), thus disparate transport in the models probably contributes to many of these differences. Satellite and aircraft measurement provide modeling tests of the various components of NO(sub y). Although some recent reaction rate measurements have led to improvements in model/measurement agreement, significant differences do remain. This presentation will provide an overview of several proposed sources and sinks of NO(sub y) and their regions of importance. Multi-dimensional modeling results for NO(sub y) and its components with comparisons to observations will also be presented.

Promoting Optimum Mental Health through Counseling: An Overview.

ERIC Educational Resources Information Center

Hinkle, J. Scott, Ed.

A broad selection of topics representing important aspects of mental health counseling are presented in 56 brief articles. Part 1, "Overview: The Evolution of Mental Health Counseling," provides definition and a discussion of training and certification. Other chapters address the history, development, and future of the field, freedom of…

The non-Federal oceanographic community: An overview

NASA Technical Reports Server (NTRS)

Swetnick, M. A.

1981-01-01

A portion of the broad domestic non-Federal oceanographic community that represents a potential market for satellite remote sensor derived oceanographic data and/or marine environmental information is presented. The overview consists of listings of individuals and/or organizations who have used, or are likely to use such data or information for scientific research, offshore engineering purposes, marine resources exploration and utilization, marine related operational applications, or coastal zone management.

Central Processing of the Chemical Senses: An Overview

PubMed Central

2010-01-01

Our knowledge regarding the neural processing of the three chemical senses has been considerably lagging behind that of our other senses. It is only during the last 25 years that significant advances have been made in our understanding of where in the human brain odors, tastants, and trigeminal stimuli are processed. Here, we provide an overview of the current knowledge of how the human brain processes chemical stimuli based on findings in neuroimaging studies using positron emission tomography and functional magnetic resonance imaging. Additionally, we provide new insights from recent meta-analyses, on the basis of all published neuroimaging studies of the chemical senses, of where the chemical senses converge in the brain. PMID:21503268

Current thinking in medical education research: an overview.

PubMed

Elledge, R

2018-04-28

Medical education is fast becoming a separate focus, and together with their clinical commitments, many clinicians now seek higher qualifications and professional accreditation in the field. Research is also developing, and there is a need for evidence-based practice in education, just as in clinical work. This review gives an overview of research into medical education, and explains the fundamentals of educational theory and the specific considerations for the quantitative and qualitative research methods that pertain to it. It also explains the application of these methods to two growing areas of research: technology-enhanced learning (TEL) and normative ethics in training. Copyright © 2018 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

An Overview of the History of Cluster Conferences

NASA Astrophysics Data System (ADS)

Horiuchi, H.

2017-06-01

An overview is given on the historical development of the cluster conference series which started at Bohum in 1969. I start with the discussion of the philosophy of Karl Wildermuth and then I make a review on the main subjects and topics in cluster conferences. Since the cluster dynamics is a main nuclear dynamics together with the mean-field dynamics, we see that development of the cluster conference has been along with the rises of many new subjects in nuclear physics itself. Examples of them include superheavy nuclei, nuclear astrophysics, neutron-rich nuclei, cluster-gas states and ab initio calculations. Finally I discuss that more activities in and attention to cluster physics are seen in recent days.

NASA Global Hawk Overview

NASA Technical Reports Server (NTRS)

Naftel, Chris

2014-01-01

The NASA Global Hawk Project is supporting Earth Science research customers. These customers include: US Government agencies, civilian organizations, and universities. The combination of the Global Hawks range, endurance, altitude, payload power, payload volume and payload weight capabilities separates the Global Hawk platform from all other platforms available to the science community. This presentation includes an overview of the concept of operations and an overview of the completed science campaigns. In addition, the future science plans, using the NASA Global Hawk System, will be presented.

Quality Assurance in Higher Education in Spain: An Overview of the Accreditation System

ERIC Educational Resources Information Center

Ríos, Cristina

2015-01-01

Accreditation has become an important issue in Spain. This paper presents an overview of Spain's accreditation system; a system which is relatively new and has evolved rapidly, fostered by legislative mandates which established accreditation bodies to regulate the quality of higher education institutions. One of the initial challenges faced by…

[The syndrome of Cotard: an overview].

PubMed

Van den Eynde, F; Debruyne, H; Portzky, M; De Saedeleer, S; Audenaert, K

2008-01-01

There is increasing controversy about whether psychiatric illnesses should be divided into categories. One of the reasons is that such a categorial system, by its very nature, cannot provide a detailed description of specific psychopathological symptoms. A patient with Cotard's syndrome, for instance, is characterised by a nihilistic delusion relating to his own body and the syndrome does not fit into any one category. We report on a case of Cotard's syndrome encountered at our clinic. To provide an overview of the characteristics of Cotard's syndrome, including its history, phenomenology, pathogenesis and treatment. A Medline search was conducted for the period 1980-2006 using the search term 'Cotard$'. This resulted in 68 publications, of which 18 were not used. Cross-references were used as well. Cotard's syndrome cannot be fitted unambiguously into any one category of the current classification system. Current evidence regarding Cotard's syndrome is based mainly on case studies and therefore no clarity can be obtained about the various aspects of the syndrome, such as prevalence, pathogenesis, treatment.

High-Intensity Focused Ultrasound Therapy: an Overview for Radiologists

PubMed Central

Kim, Young-sun; Choi, Min Joo; Lim, Hyo Keun; Choi, Dongil

2008-01-01

High-intensity focused ultrasound therapy is a novel, emerging, therapeutic modality that uses ultrasound waves, propagated through tissue media, as carriers of energy. This completely non-invasive technology has great potential for tumor ablation as well as hemostasis, thrombolysis and targeted drug/gene delivery. However, the application of this technology still has many drawbacks. It is expected that current obstacles to implementation will be resolved in the near future. In this review, we provide an overview of high-intensity focused ultrasound therapy from the basic physics to recent clinical studies with an interventional radiologist's perspective for the purpose of improving the general understanding of this cutting-edge technology as well as speculating on future developments. PMID:18682666

Measuring School Climate: An Overview of Measurement Scales

ERIC Educational Resources Information Center

Kohl, Diane; Recchia, Sophie; Steffgen, Georges

2013-01-01

Background: School climate is a heterogeneous concept with a multitude of standardised and validated instruments available to measure it. Purpose: This overview of measurement scales aims to provide researchers with short summaries of some of the self-report instruments in existence, especially in relation to the link between school climate and…

Frameworks for Examining Comprehension and Discourse: An Overview.

ERIC Educational Resources Information Center

Carey, Robert F.; Smith, Sharon L.

Overviews of schema theory, which focuses on the cognitive operations engaged in by the reader, and discourse analysis, which focuses on structural characteristics of the text itself, are presented in this paper. The first section explains the notion of cognitive schemata (patterns of expectations that are applied to incoming information) and…

Policies for biosimilar uptake in Europe: An overview

PubMed Central

Vulto, Arnold G.; Huys, Isabelle; Dylst, Pieter; Godman, Brian; Keuerleber, Simon; Claus, Barbara; Dimitrova, Maria; Petrova, Guenka; Sović-Brkičić, Ljiljana; Slabý, Juraj; Šebesta, Robin; Laius, Ott; Karr, Allan; Beck, Morgane; Martikainen, Jaana E.; Selke, Gisbert W.; Spillane, Susan; McCullagh, Laura; Trifirò, Gianluca; Vella Bonanno, Patricia; Mack, Asbjørn; Fogele, Antra; Viksna, Anita; Władysiuk, Magdalena; Mota-Filipe, Helder; Meshkov, Dmitry; Kalaba, Marija; Mencej Bedrač, Simona; Fürst, Jurij; Zara, Corrine; Skiöld, Peter; Magnússon, Einar; Simoens, Steven

2017-01-01

Background Across European countries, differences exist in biosimilar policies, leading to variations in uptake of biosimilars and divergences in savings all over Europe. Objectives The aim of this article is to provide an overview of different initiatives and policies that may influence the uptake of biosimilars in different European countries. Recommendations will be formulated on how to create sustainable uptake. Methods An overview of policies on biosimilars was obtained via a questionnaire, supplemented with relevant articles. Topics were organized in five themes: availability, pricing, reimbursement, demand-side policies, and recommendations to enhance uptake. Results In all countries studied, biological medicines are available. Restrictions are mainly dependent on local organization of the healthcare system. Countries are willing to include biosimilars for reimbursement, but for commercial reasons they are not always marketed. In two thirds of countries, originator and biosimilar products may be subjected to internal reference pricing systems. Few countries have implemented specific incentives targeting physicians. Several countries are implementing pharmacist substitution; however, the scope and rules governing such substitution tend to vary between these countries. Reported educational policies tend to target primarily physicians, whereas fewer initiatives were reported for patients. Recommendations as proposed by the different country experts ranged from the need for information and communication on biosimilars to competitive pricing, more support for switching and guidance on substitution. Conclusions Most countries have put in place specific supply-side policies for promoting access to biosimilars. To supplement these measures, we propose that investments should be made to clearly communicate on biosimilars and educate stakeholders. Especially physicians need to be informed on the entry and use of biosimilars in order to create trust. When physicians

[Transcranial magnetic stimulation (TMS), inhibition processes and attention deficit/hyperactivity disorder (ADHD) - an overview].

PubMed

Hoegl, Thomas; Bender, Stephan; Buchmann, Johannes; Kratz, Oliver; Moll, Gunther H; Heinrich, Hartmut

2014-11-01

Motor system excitability can be tested by transcranial magnetic stimulation CFMS). In this article, an overview of recent methodological developments and research findings related to attention deficit/hyperactivity disorder (ADHD) is provided. Different TMS parameters that reflect the function of interneurons in the motor cortex may represent neurophysiological markers of inhibition in ADHD, particularly the so-called intracortical inhibition. In children with a high level of hyperactivity and impulsivity, intracortical inhibition was comparably low at rest as shortly before the execution of a movement. TMS-evoked potentials can also be measured in the EEG so that investigating processes of excitability is not restricted to motor areas in future studies. The effects of methylphenidate on motor system excitability may be interpreted in the sense of a 'fine-tuning' with these mainly dopaminergic effects also depending on genetic parameters (DAT1 transporter). A differentiated view on the organization of motor control can be achieved by a combined analysis of TMS parameters and event-related potentials. Applying this bimodal approach, strong evidence for a deviant implementation of motor control in children with ADHD and probably compensatory mechanisms (with involvement of the prefrontal cortex) was obtained. These findings, which contribute to a better understanding of hyperactivity/impulsivity, inhibitory processes and motor control in ADHD as well as the mechanisms of medication, underline the relevance of TMS as a neurophysiological method in ADHD research.

FAA center for aviation systems reliability: an overview

NASA Astrophysics Data System (ADS)

Brasche, Lisa J. H.

1996-11-01

The FAA Center for Aviation Systems Reliability has as its objectives: to develop quantitative nondestructive evaluation (NDE) methods for aircraft structures and materials, including prototype instrumentation, software, techniques and procedures; and to develop and maintain comprehensive education and training programs specific to the inspection of aviation structures. The program, which includes contributions from Iowa State University, Northwestern University, Wayne State University, Tuskegee University, AlliedSignal Propulsion Engines, General Electric Aircraft Engines and Pratt and Whitney, has been in existence since 1990. Efforts under way include: development of inspection for adhesively bonded structures; detection of corrosion; development of advanced NDE concepts that form the basis for an inspection simulator; improvements of titanium inspection as part of the Engine Titanium Consortium; development of education and training program. An overview of the efforts underway will be provided with focus on those technologies closest to technology transfer.

Antibacterial Derivatives of Marine Algae: An Overview of Pharmacological Mechanisms and Applications

PubMed Central

Shannon, Emer; Abu-Ghannam, Nissreen

2016-01-01

The marine environment is home to a taxonomically diverse ecosystem. Organisms such as algae, molluscs, sponges, corals, and tunicates have evolved to survive the high concentrations of infectious and surface-fouling bacteria that are indigenous to ocean waters. Both macroalgae (seaweeds) and microalgae (diatoms) contain pharmacologically active compounds such as phlorotannins, fatty acids, polysaccharides, peptides, and terpenes which combat bacterial invasion. The resistance of pathogenic bacteria to existing antibiotics has become a global epidemic. Marine algae derivatives have shown promise as candidates in novel, antibacterial drug discovery. The efficacy of these compounds, their mechanism of action, applications as antibiotics, disinfectants, and inhibitors of foodborne pathogenic and spoilage bacteria are reviewed in this article. PMID:27110798

An overview of the F-117A avionics flight test program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Silz, R.

1992-02-01

This paper is an overview of the history of the F-117A avionics flight test program. System design concepts and equipment selections are explored followed by a review of full scale development and full capability development testing. Flight testing the Weapon System Computational Subsystem upgrade and the Offensive Combat Improvement Program are reviewed. Current flight test programs and future system updates are highlighted.

Division Overview

NASA Technical Reports Server (NTRS)

Emerson, Dawn

2016-01-01

This presentation provides an overview of the research and engineering in the competency fields of advanced communications and intelligent systems with emphasis on advanced technologies, architecture definition and system development for application in current and future aeronautics and space systems.

Internationalization, Deregulation and the Expansion of Higher Education in Korea: An Historical Overview

ERIC Educational Resources Information Center

Green, Christopher

2015-01-01

The purpose of this article is to provide an overview of internationalization policies in Korean higher education since 1993. Deregulation was a key strategy of Korean governments, but this strategy has led to an increasing oversupply of enrolment capacity. In response, the current government is implementing a system of reregulation to reduce the…

Introducing the LHC in the Classroom: An Overview of Education Resources Available

ERIC Educational Resources Information Center

Wiener, Gerfried J.; Woithe, Julia; Brown, Alexander; Jende, Konrad

2016-01-01

In the context of the recent re-start of CERN's Large Hadron Collider (LHC) and the challenge presented by unidentified falling objects (UFOs), we seek to facilitate the introduction of high energy physics in the classroom. Therefore, this paper provides an overview of the LHC and its operation, highlighting existing education resources, and…

An overview of Brazilian experience on measuring runoff and soil loss rates

USDA-ARS?s Scientific Manuscript database

Efforts have been made to determine soil erosion rates using runoff plots, mainly in the last century. In Brazil, the first experimental studies in plot-scale monitoring sites started in the 1940s. Thus, we aim to show an overview of plot-scale studies under natural rainfall over the country. We rev...

Application of Learner Corpora to Second Language Learning and Teaching: An Overview

ERIC Educational Resources Information Center

Xu, Qi

2016-01-01

The paper gives an overview of learner corpora and their application to second language learning and teaching. It is proposed that there are four core components in learner corpus research, namely, corpus linguistics expertise, a good background in linguistic theory, knowledge of SLA theory, and a good understanding of foreign language teaching…

Modeling of Chronic Myeloid Leukemia: An Overview of In Vivo Murine and Human Xenograft Models

PubMed Central

Vellenga, Edo

2016-01-01

Over the past years, a wide variety of in vivo mouse models have been generated in order to unravel the molecular pathology of Chronic Myeloid Leukemia (CML) and to develop and improve therapeutic approaches. These models range from (conditional) transgenic models, knock-in models, and murine bone marrow retroviral transduction models followed by transplantation. With the advancement of immunodeficient xenograft models, it has become possible to use human stem/progenitor cells for in vivo studies as well as cells directly derived from CML patients. These models not only mimic CML but also have been instrumental in uncovering various fundamental mechanisms of CML disease progression and tyrosine kinase inhibitor (TKI) resistance. With the availability of iPSC technology, it has become feasible to derive, maintain, and expand CML subclones that are at least genetically identical to those in patients. The following review provides an overview of all murine as well as human xenograft models for CML established till date. PMID:27642303

Irradiation treatment of pharmaceutical and personal care products (PPCPs) in water and wastewater: An overview

NASA Astrophysics Data System (ADS)

Wang, Jianlong; Chu, Libing

2016-08-01

Pharmaceutical and personal care products (PPCPs), especially the pharmaceutically active compounds (PhACs) such as antibiotics and hormones have attracted great concerns worldwide for their persistence and potential threat to ecosystem and public health. This paper presents an overview on the ionizing irradiation-induced degradation of PPCPs in aqueous solution. Parameters that affect PPCPs degradation, such as the absorbed dose, solution pH, dose rate, water matrices and the presence of some inorganic ions and humic acid are evaluated. The mechanism and pathways of radiolytic degradation of PPCPs are reviewed. In many cases, PPCPs such as antibiotics and X-ray contrast agent could be removed completely by radiation, but a higher absorbed dose was needed for their mineralization and toxicity reduction. The combination of ionizing irradiation with other methods such as H2O2, ozonation and TiO2 nanoparticles could improve the degradation efficacy and reduce the cost. Ionizing irradiation is a promising alternative for degradation of PPCPs in aqueous solution.

An Overview of Head and Neck Malignancy with Perineural Spread

PubMed Central

Panizza, Benedict J.

2016-01-01

This article provides an overview of perineural spread of head and neck malignancy. It defines the problem and explores some of the unique features, which occur with this pathology. The expectation is for a better understanding of this extraordinary disease, hopefully leading to earlier diagnosis and for a more consistent reporting of results. It summarizes the topics to be covered in this special edition, which should leave the reader with a fairly complete understanding of the contemporary issues of perineural spread. PMID:27123383

An Overview of Head and Neck Malignancy with Perineural Spread.

PubMed

Panizza, Benedict J

2016-04-01

This article provides an overview of perineural spread of head and neck malignancy. It defines the problem and explores some of the unique features, which occur with this pathology. The expectation is for a better understanding of this extraordinary disease, hopefully leading to earlier diagnosis and for a more consistent reporting of results. It summarizes the topics to be covered in this special edition, which should leave the reader with a fairly complete understanding of the contemporary issues of perineural spread.

An overview of near-barrier fusion studies with stable beams

NASA Astrophysics Data System (ADS)

Trotta, M.; Stefanini, A. M.; Beghini, S.; Behera, B. R.; Corradi, L.; Fioretto, E.; Gadea, A.; Itkis, M. G.; Knyazheva, G. N.; Kondratiev, N. A.; Kozulin, E. M.; Mărginean, N.; Mason, P.; Montagnoli, G.; Pokrovsky, I. V.; Sagaidak, R. N.; Scarlassara, F.; Silvestri, R.; Szilner, S.

2007-05-01

An overview of results in fusion studies with stable beams spanning different mass regions and energy ranges is presented. The advantages offered by studying channel coupling effects, involving low-lying excited states of the colliding nuclei, as well as the difficulties in understanding the influence of transfer couplings on fusion, are firstly remarked. The competition of fusion with quasi-fission in heavy systems and the unexpected steep falloff of fusion cross sections at far sub-barrier energies are finally discussed.

An Educator's Introduction to Energy Concepts: Overview Packets.

ERIC Educational Resources Information Center

Maine Audubon Society, Falmouth.

This publication provides a broad overview of energy and related issues for teachers and others who want to improve their understanding of these issues. Included in this publication are discussions of: (1) elementary physics related to energy; (2) energy sources, including topics such as renewable and non-renewable resources and fossil fuels; (3)…

Aesthetic Response: An Overview of Selected Theories and the Postulation of a Model.

ERIC Educational Resources Information Center

King, Alison

In response to a growing interest among educators in improving aesthetic education, this paper explores aesthetic response, defined as what happens in the mind and body of a person who encounters an aesthetic object or phenomenon. An initial section overviews the major theories of aesthetic response, including the work of Plato, Aristotle, Freud,…

Optimizing Wartime Materiel Delivery: An Overview of DoD containerization. Volume 3. Annotated Bibliography

DOT National Transportation Integrated Search

1988-10-01

This annotated bibliography, Volume III of the study entitled, Optimizing Wartime Materiel Delivery: An overview of DOD Containerization Efforts, documents studies related to containerization. Several objectives of the study were defined. These inclu...

Childhood Anxiety Disorders: An Overview of Recent Guides for Professionals and Parents

ERIC Educational Resources Information Center

Weems, Carl F.

2005-01-01

This article provides an overview of recent texts devoted to childhood anxiety disorders. The focus is on books that have been published since 2000 that are designed for professionals desiring to gain knowledge of childhood anxiety and for parents to help them understand and assist children with anxiety problems. The books for professionals are…

The application and technology of implantable neuromuscular stimulators: an introduction and overview.

PubMed

Jarvis, J C; Salmons, S

2001-01-01

The design of an implantable neuromuscular stimulator represents a trade-off in which the desire to maximise functionality and operational life competes with the need for the implanted device to be small, reliable, safe, and easy to use. In this introduction and overview we consider the basic problems and the different approaches to their solution.

Rainfall-induced landslides in Puerto Rico: An overview

USGS Publications Warehouse

Pando, M.A.; Ruiz, M.E.; Larsen, M.C.

2005-01-01

Rainfall-induced landslides are common in Puerto Rico (PR). The presence of steep slopes in mountainous terrain, coupled with weathered soils and intense rainfall, leads to severe slope-stability problems throughout the island. Episodic triggering events such as hurricanes and earthquakes further exacerbate these problems. All physiographic provinces of the island have experienced landslides. The stability of natural and man-made slopes is a serious concern for government authorities and the civil engineering community in Puerto Rico. This paper presents an overview of the rainfall induced landslide problem in PR, a summary of literature published on this subject, and proposes a rainfall intensity landslide threshold based on landslide events data from 1959 to 2003. This threshold can be used as part of a potential landslide warning system.

Systems biology approaches to evaluate arsenic toxicity and carcinogenicity: an overview.

PubMed

Bhattacharjee, Pritha; Chatterjee, Debmita; Singh, Keshav K; Giri, Ashok K

2013-08-01

Long term exposure to arsenic, either through groundwater, food stuff or occupational sources, results in a plethora of dermatological and non-dermatological health effects including multi-organ cancer and early mortality. Several epidemiological studies, across the globe have reported arsenic-induced health effects and cancerous outcomes; but the prevalence of such diseases varies depending on environmental factors (geographical location, exposure level), and genetic makeup (and variants thereof); which is further modulated by several other factors like ethnicity, age-sex, smoking status, diet, etc. It is also interesting to note that, chronic arsenic exposure to a similar extent, even among the same family members, result in wide inter-individual variations. To understand the adverse effect of this toxic metabolite on biological system (cellular targets), and to unravel the underlying molecular basis (at the level of transcript, proteome, or metabolite), a holistic, systems biology approach was taken. Due to the paradoxical nature and unavailability of any suitable animal model system; the literature review is primarily based on cell line and population based studies. Thus, here we present a comprehensive review on the systems biology approaches to explore the underlying mechanism of arsenic-induced carcinogenicity, along with our own observations and an overview of mitigation strategies and their effectiveness till date. Copyright © 2013 Elsevier GmbH. All rights reserved.

An overview of renal metabolomics.

PubMed

Kalim, Sahir; Rhee, Eugene P

2017-01-01

The high-throughput, high-resolution phenotyping enabled by metabolomics has been applied increasingly to a variety of questions in nephrology research. This article provides an overview of current metabolomics methodologies and nomenclature, citing specific considerations in sample preparation, metabolite measurement, and data analysis that investigators should understand when examining the literature or designing a study. Furthermore, we review several notable findings that have emerged in the literature that both highlight some of the limitations of current profiling approaches, as well as outline specific strengths unique to metabolomics. More specifically, we review data on the following: (i) tryptophan metabolites and chronic kidney disease onset, illustrating the interpretation of metabolite data in the context of established biochemical pathways; (ii) trimethylamine-N-oxide and cardiovascular disease in chronic kidney disease, illustrating the integration of exogenous and endogenous inputs to the blood metabolome; and (iii) renal mitochondrial function in diabetic kidney disease and acute kidney injury, illustrating the potential for rapid translation of metabolite data for diagnostic or therapeutic aims. Finally, we review future directions, including the need to better characterize interperson and intraperson variation in the metabolome, pool existing data sets to identify the most robust signals, and capitalize on the discovery potential of emerging nontargeted methods. Copyright © 2016 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

Overview.

ERIC Educational Resources Information Center

Kain, Craig D.; And Others

This document consists of the first section of a book written to educate and inform those in the helping professions on how to deal with Acquired Immune Deficiency Syndrome (AIDS). The two chapters in this first section present an overview of the AIDS crisis and provide a foundation for the rest of the book. "Emerging Trends: AIDS Today and in the…

Measure Guideline: Wall Air Sealing and Insulation Methods in Existing Homes; An Overview of Opportunity and Process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roberts, S.; Stephenson, R.

2012-09-01

This guide provides renovators and retrofit contractors an overview of considerations when including wall air sealing and insulation in an energy retrofit project. It also outlines the potential project risks, various materials for insulating, possible field inspections needed, installation procedures, as well as the benefits and drawbacks. The purpose of this document is to provide the outline of the overview and process of insulating and air sealing walls so that home retrofit professionals can identify approaches to air sealing and insulation measures.

Lymphohematopoietic Cancers Induced by Chemicals and Other Agents: Overview and Implications for Risk Assessment (External Review Draft)

EPA Science Inventory

This draft report provides an overview of the types of mechanisms underlying the lymphohematopoietic cancers induced by chemical agents and radiation in humans, with a primary emphasis on leukemia and leukemia-inducing agents. It focuses on how mechanistic information on human l...

β-Thalassemia intermedia: a comprehensive overview and novel approaches.

PubMed

Asadov, Chingiz; Alimirzoeva, Zohra; Mammadova, Tahira; Aliyeva, Gunay; Gafarova, Shahla; Mammadov, Jeyhun

2018-01-29

β-Thalassemia intermedia is a clinical condition of intermediate gravity between β-thalassemia minor, the asymptomatic carrier, and β-thalassemia major, the transfusion-dependent severe anemia. It is characterized by a significant clinical polymorphism, which is attributable to its genetic heterogeneity. Ineffective erythropoiesis, chronic anemia, and iron overload contribute to the clinical complications of thalassemia intermedia through stepwise pathophysiological mechanisms. These complications, including splenomegaly, extramedullary erythropoiesis, iron accumulation, leg ulcers, thrombophilia, and bone abnormalities can be managed via fetal hemoglobin induction, occasional transfusions, chelation, and in some cases, stem cell transplantation. Given its clinical diversity, thalassemia intermedia patients require tailored approaches to therapy. Here we present an overview and novel approaches to the genetic basis, pathophysiological mechanisms, clinical complications, and optimal management of thalassemia intermedia.

Family and Family Change in Ireland: An Overview

ERIC Educational Resources Information Center

Canavan, John

2012-01-01

In Ireland, historically and in the current era, family has been a central concern for society and the State. This article provides a descriptive overview of family life in Ireland and of major family-related changes over the past 40 years. It presents a general framework of analysis within which these changes can be understood, considers the…

COLLECTION SYSTEM SOLIDS CONTROL: OVERVIEW OF AN EPA WET-WEATHER FLOW RESEARCH PROGRAM

EPA Science Inventory

This paper presents an historical overview of the sewer-solids control projects conducted by the Wet-Weather Flow Research Program of the US EPA. Research includes studies of the causes of sewer-solids deposition and development/evaluation of control methods that can prevent sewe...

The MSFC Systems Engineering Guide: An Overview and Plan

NASA Technical Reports Server (NTRS)

Shelby, Jerry; Thomas, L. Dale

2007-01-01

This paper describes the guiding vision, progress to date and the plan forward for development of the Marshall Space Flight Center (MSFC) Systems Engineering Guide (SEG), a virtual systems engineering handbook and archive that describes the system engineering processes used by MSFC in the development of ongoing complex space systems such as the Ares launch vehicle and forthcoming ones as well. It is the intent of this website to be a "One Stop Shop' for MSFC systems engineers that will provide tutorial information, an overview of processes and procedures and links to assist system engineering with guidance and references, and provide an archive of relevant systems engineering artifacts produced by the many NASA projects developed and managed by MSFC over the years.

Cellular immunotherapy of cancer: an overview and future directions.

PubMed

Tao, Ziqi; Li, Shuang; Ichim, Thomas E; Yang, Junbao; Riordan, Neil; Yenugonda, Venkata; Babic, Ivan; Kesari, Santosh

2017-06-01

The clinical success of checkpoint inhibitors has led to a renaissance of interest in cancer immunotherapies. In particular, the possibility of ex vivo expanding autologous lymphocytes that specifically recognize tumor cells has attracted much research and clinical trial interest. In this review, we discuss the historical background of tumor immunotherapy using cell-based approaches, and provide some rationale for overcoming current barriers to success of autologous immunotherapy. An overview of adoptive transfer of lymphocytes, tumor infiltrating lymphocytes and dendritic cell therapies is provided. We conclude with discussing the possibility of gene-manipulating immune cells in order to augment therapeutic activity, including silencing of the immune-suppressive zinc finger orphan nuclear receptor, NR2F6, as an attractive means of overcoming tumor-associated immune suppression.

An Overview of R in Health Decision Sciences.

PubMed

Jalal, Hawre; Pechlivanoglou, Petros; Krijkamp, Eline; Alarid-Escudero, Fernando; Enns, Eva; Hunink, M G Myriam

2017-10-01

As the complexity of health decision science applications increases, high-level programming languages are increasingly adopted for statistical analyses and numerical computations. These programming languages facilitate sophisticated modeling, model documentation, and analysis reproducibility. Among the high-level programming languages, the statistical programming framework R is gaining increased recognition. R is freely available, cross-platform compatible, and open source. A large community of users who have generated an extensive collection of well-documented packages and functions supports it. These functions facilitate applications of health decision science methodology as well as the visualization and communication of results. Although R's popularity is increasing among health decision scientists, methodological extensions of R in the field of decision analysis remain isolated. The purpose of this article is to provide an overview of existing R functionality that is applicable to the various stages of decision analysis, including model design, input parameter estimation, and analysis of model outputs.

Nitrogen dynamics in flooded soil systems: an overview on concepts and performance of models

PubMed Central

Nurulhuda, Khairudin; Gaydon, Donald S; Jing, Qi; Zakaria, Mohamad P; Struik, Paul C

2017-01-01

Abstract Extensive modelling studies on nitrogen (N) dynamics in flooded soil systems have been published. Consequently, many N dynamics models are available for users to select from. With the current research trend, inclined towards multidisciplinary research, and with substantial progress in understanding of N dynamics in flooded soil systems, the objective of this paper is to provide an overview of the modelling concepts and performance of 14 models developed to simulate N dynamics in flooded soil systems. This overview provides breadth of knowledge on the models, and, therefore, is valuable as a first step in the selection of an appropriate model for a specific application. © 2017 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. PMID:28940491

Drugs and the Internet: An Overview of the Threat to America's Youth.

ERIC Educational Resources Information Center

Department of Justice, Washington, DC.

This report is an overview of the threat that certain Internet websites pose to adolescents and young adults in the United States. This preliminary baseline is intended to assist policymakers in countering this threat to America's youth. This report focuses on websites that promote or facilitate the production, use, and sale of MDMA, GHB, and LSD,…

The Early College High School Initiative: An Overview of Five Evaluation Years

ERIC Educational Resources Information Center

Berger, Andrea; Adelman, Nancy; Cole, Susan

2010-01-01

In 2002, the Bill & Melinda Gates Foundation started the Early College High School Initiative (ECHSI). Through this initiative, more than 200 Early College Schools (ECSs) opened by fall 2009. All of the schools aim to provide underserved students access to college classes while in high school. This article will provide an overview of the first 6…

Navigating rough waters: an overview of psychological aspects of surrogacy.

PubMed

Ciccarelli, Janice C; Beckman, Linda J

2005-03-01

This article provides an overview of the social and psychological aspects surrounding the surrogacy process including attitudes about surrogacy, perceptions and problems of surrogate mothers and intended/social parents, and questions concerning children resulting from contractual parenting. Review of the literature on contractual parenting reveals a wealth of discussion about the ethical, moral, legal, and psychological implications, but limited empirical data on the psychological and social aspects. Future research can provide empirical evidence as a foundation for counseling at all phases of the surrogacy process.

Acquiring, recording, and analyzing pathology data from experimental mice: an overview.

PubMed

Scudamore, Cheryl L

2014-03-21

Pathology is often underutilized as an end point in mouse studies in academic research because of a lack of experience and expertise. The use of traditional pathology techniques including necropsy and microscopic analysis can be useful in identifying the basic processes underlying a phenotype and facilitating comparison with equivalent human diseases. This overview aims to provide a guide and reference to the acquisition, recording, and analysis of high-quality pathology data from experimental mice in an academic research setting. Copyright © 2014 John Wiley & Sons, Inc.

ICESat-2: An overview of science objectives, status, data products and expected performance

NASA Astrophysics Data System (ADS)

Neumann, T.; Markus, T.; Anthony, M.

2016-12-01

NASA's Ice, Cloud, and land Elevation Satellite-2's (ICESat-2) mission objectives are to quantify polar ice sheet contributions to sea level change, quantify regional signatures of ice sheet changes to assess driving mechanisms, estimate sea ice thickness, and to enable measurements of canopy height as a basis for estimating large-scale biomass. With a scheduled launch date in late 2017 most of the flight hardware has been assembled, integrated and tested and algorithm implementation for its standard geophysical products is well underway. The spacecraft, built by Orbital ATK, is completed and is undergoing testing. ICESat-2's single instrument, the Advanced Topographic Laser Altimeter System (ATLAS), is built by NASA Goddard Space Flight Center and by the time of the Fall Meeting will be undergoing integration and testing with the spacecraft, becoming the ICESat-2 observatory. In parallel, high level geophysical data products and associated algorithms are in development using airborne laser altimeter data. This presentation will give an overview of the design of ICESat-2, of its hardware and software status, as well as examples of ICESat-2's coverage and what the data will look like.

Volume and intensity of Medicare physicians' services: An overview

PubMed Central

Kay, Terrence L.

1990-01-01

From 1978 to 1987, Medicare spending for physicians' services increased at annual compound rates of 16 percent, far exceeding increases expected based on inflation and increases in beneficiaries. As a result, Medicare spending for Part B physicians' services has attracted considerable attention. This article contains an overview of expenditure trends for Part B physicians' services, a summary of recent research findings on issues related to volume and intensity of physicians' services, and a discussion of options for controlling volume and intensity. The possible impact of the recently enacted relative-value-based fee schedule on volume and intensity of services is discussed briefly. PMID:10113398

An overview of the NASA rotary engine research program

NASA Technical Reports Server (NTRS)

Meng, P. R.; Hady, W. F.

1984-01-01

A brief overview and technical highlights of the research efforts and studies on rotary engines over the last several years at the NASA Lewis Research Center are presented. The test results obtained from turbocharged rotary engines and preliminary results from a high performance single rotor engine were discussed. Combustion modeling studies of the rotary engine and the use of a Laser Doppler Velocimeter to confirm the studies were examined. An in-house program in which a turbocharged rotary engine was installed in a Cessna Skymaster for ground test studies was reviewed. Details are presented on single rotor stratified charge rotary engine research efforts, both in-house and on contract.

Towards an integrated model of nursing competence: an overview of the literature reviews and concept analysis.

PubMed

Caruso, Roberto; Fida, Roberta; Sili, Alessandro; Arrigoni, Cristina

2016-01-01

Competence is considered a fundamental element when measuring a nurse's or student's ability to provide nursing care, but there is no consensus on what competence really is. This paper aims to review the existing meanings and models of nursing competence. The overview of literature reviews and concept analysis was performed through a search on Pubmed, Cinahl and PsychINFO from January 2005 to September 2014. It included key words, such as: Competence Model; Professional Competence; Nursing Competence; Competency Model; Professional Competency; Nursing Competency. A total of 14 papers were found, coming from educational or clinical nursing field. It was possible to identify some common themes: description of competence determinants; confu- sion around the competence concept; lack in competence evaluation; lack when competence have to be operationalized. The overview results, enriched by the literature coming out from the organiza- tional studies, build the conceptual basis of an integrated model of nursing competence. More empirical research is needed to test the theoretical assumptions.

Biomarkers: an overview for oncology nurses.

PubMed

Richmond, Ellen S; Dunn, Debra

2012-05-01

To provide an overview of the basic principles of biomarker use in clinical oncology practice and discuss the range of biomarker forms (from genes to constitutional characteristics), biomarker functions (both disease- and drug-related), modalities (protein expression patterns to patient history), the criteria for biomarker validation, and the integral role of bioinformatics. Published nursing and medical literature. The premise of nursing assessment is the same as that of biomarker use - biological variables that appear at one level of biological organization (eg, molecule, organelle, cell, tissue, organ, and organism) correspond to processes or events occurring at other levels of biologic organization. The advent of genomic technologies has logarithmically increased the volume of biomarkers, which are expected to provide new insights that improve patient care. Nurses and patients will benefit greatly from the incorporation of molecular biomarkers into patient care. Nurses will be able to better assess (and anticipate) patient needs with the new insights that are available in the post-genomic, personalized medicine era of health care. Although the rapid rate of technological changes and new discoveries will require continuing concerted educational efforts, the improved quality of patient care will be rewarded by better outcomes. Published by Elsevier Inc.

Spaceflight-Induced Intracranial Hypertension: An Overview

NASA Technical Reports Server (NTRS)

Traver, William J.

2011-01-01

This slide presentation is an overview of the some of the known results of spaceflight induced intracranial hypertension. Historical information from Gemini 5, Apollo, and the space shuttle programs indicated that some vision impairment was reported and a comparison between these historical missions and present missions is included. Optic Disc Edema, Globe Flattening, Choroidal Folds, Hyperopic Shifts and Raised Intracranial Pressure has occurred in Astronauts During and After Long Duration Space Flight. Views illustrate the occurrence of Optic Disc Edema, Globe Flattening, and Choroidal Folds. There are views of the Arachnoid Granulations and Venous return, and the question of spinal or venous compliance issues is discussed. The question of increased blood flow and its relation to increased Cerebrospinal fluid (CSF) is raised. Most observed on-orbit papilledema does not progress, and this might be a function of plateau homeostasis for the higher level of intracranial pressure. There are seven cases of astronauts experiencing in flight and post flight symptoms, which are summarized and follow-up is reviewed along with a comparison of the treatment options. The question is "is there other involvement besides vision," and other Clinical implications are raised,

Electronic waste management approaches: an overview.

PubMed

Kiddee, Peeranart; Naidu, Ravi; Wong, Ming H

2013-05-01

Electronic waste (e-waste) is one of the fastest-growing pollution problems worldwide given the presence if a variety of toxic substances which can contaminate the environment and threaten human health, if disposal protocols are not meticulously managed. This paper presents an overview of toxic substances present in e-waste, their potential environmental and human health impacts together with management strategies currently being used in certain countries. Several tools including life cycle assessment (LCA), material flow analysis (MFA), multi criteria analysis (MCA) and extended producer responsibility (EPR) have been developed to manage e-wastes especially in developed countries. The key to success in terms of e-waste management is to develop eco-design devices, properly collect e-waste, recover and recycle material by safe methods, dispose of e-waste by suitable techniques, forbid the transfer of used electronic devices to developing countries, and raise awareness of the impact of e-waste. No single tool is adequate but together they can complement each other to solve this issue. A national scheme such as EPR is a good policy in solving the growing e-waste problems. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

Diagnostic instruments for behavioural addiction: an overview

PubMed Central

Albrecht, Ulrike; Kirschner, Nina Ellen; Grüsser, Sabine M.

2007-01-01

In non-substance-related addiction, the so-called behavioural addiction, no external psychotropic substances are consumed. The psychotropic effect consists of the body’s own biochemical processes induced only by excessive activities. Until recently, knowledge was limited with respect to clinically relevant excessive reward-seeking behaviour, such as pathological gambling, excessive shopping and working which meet diagnostic criteria of dependent behaviour. To date, there is no consistent concept for diagnosis and treatment of excessive reward-seeking behaviour, and its classification is uncertain. Therefore, a clear conceptualization of the so-called behavioural addictions is of great importance. The use of adequate diagnostic instruments is necessary for successful therapeutical implications. This article provides an overview of the current popular diagnostic instruments assessing the different forms of behavioural addiction. Especially in certain areas there are only few valid and reliable instruments available to assess excessive rewarding behaviours that fulfill the criteria of addiction. PMID:19742294

New psychoactive substances: an overview on recent publications on their toxicodynamics and toxicokinetics.

PubMed

Meyer, Markus R

2016-10-01

This review article covers English-written and PubMed-listed review articles and original studies published between January 2015 and April 2016 dealing with the toxicodynamics and toxicokinetics of new psychoactive substances. Compounds covered include stimulants and entactogens, synthetic cannabinoids, tryptamines, NBOMes, phencyclidine-like drugs, benzodiazepines, and opioids. First, an overview and discussion is provided on timely review articles followed by an overview and discussion on recent original studies. Both sections are then concluded by an opinion on these latest developments. This review shows that the NPS market is still highly dynamic and that the data published on their toxicodynamics and toxicokinetics can hardly keep pace with the appearance of new entities. However, data available are very helpful to understand and predict how NPS may behave in severe intoxication. The currently best-documented parameter is the in vitro metabolism of NPS, a prerequisite to allow detection of NPS in biological matrices in cases of acute intoxications or chronic consumption. However, additional data such as their chronic toxicity are still lacking.

Extreme winds and tornadoes: an overview

DOE Office of Scientific and Technical Information (OSTI.GOV)

McDonald, J.R.

1985-01-01

The objective of this course on extreme winds, hurricanes and tornadoes is to provide an overview of these natural phenomenon from the perspective of design of new buildings and structures or the evaluation of existing ones. Information is directly applicable to design and evaluation processes. The premise is that the facility under consideration, which may consist of various buildings, structures, processing equipment, stacks, ventilation ducts, etc., can be classified into certain categories, depending on the importance of the mission performed in the facility or the hazard that is presented by the particular operation. Having classified the facility into an appropriatemore » category will automatically define certain design goals for the facility. The design goals are then met by selecting a design wind speed that is appropriate for the specified exceedance probability and by following certain specified design procedures. The problem then is to determine appropriate wind loads and other applicable loads, including dead loads, live loads, seismic loads and other loads that may act on the structures. The design process can then proceed in the usual manner. In the case of existing facilities the strengths of the various structural elements, subsystems and systems are evaluated and these strengths are related to wind speeds that would result in failure to meet the design goals. 12 refs.« less

Adversarial Collaboration Decision-Making: An Overview of Social Quantum Information Processing

DTIC Science & Technology

2002-01-01

collaborative decision - making (CDM) to solve problems is an aspect of human behavior least yielding to rational predictions. To reduce the complexity of CDM...increases. Implications for C2 decision - making are discussed. Overview of research Game theory was one of the first rational approaches to the study of...Psychologist, 36, 343-356. Lawless, W.F. (2001), The quantum of social action and the function of emotion in decision - making , Proceedings, Emotional and

IPG Power Grid Overview

NASA Technical Reports Server (NTRS)

Hinke, Thomas

2003-01-01

This presentation will describe what is meant by grids and then cover the current state of the IPG. This will include an overview of the middleware that is key to the operation of the grid. The presentation will then describe some of the future directions that are planned for the IPG. Finally the presentation will conclude with a brief overview of the Global Grid Forum, which is a key activity that will contribute to the successful availability of grid components.

Mechanical properties of human atherosclerotic intima tissue.

PubMed

Akyildiz, Ali C; Speelman, Lambert; Gijsen, Frank J H

2014-03-03

Progression and rupture of atherosclerotic plaques in coronary and carotid arteries are the key processes underlying myocardial infarctions and strokes. Biomechanical stress analyses to compute mechanical stresses in a plaque can potentially be used to assess plaque vulnerability. The stress analyses strongly rely on accurate representation of the mechanical properties of the plaque components. In this review, the composition of intima tissue and how this changes during plaque development is discussed from a mechanical perspective. The plaque classification scheme of the American Heart Association is reviewed and plaques originating from different vascular territories are compared. Thereafter, an overview of the experimental studies on tensile and compressive plaque intima properties are presented and the results are linked to the pathology of atherosclerotic plaques. This overview revealed a considerable variation within studies, and an enormous dispersion between studies. Finally, the implications of the dispersion in experimental data on the clinical applications of biomechanical plaque modeling are presented. Suggestions are made on mechanical testing protocol for plaque tissue and on using a standardized plaque classification scheme. This review identifies the current status of knowledge on plaque mechanical properties and the future steps required for a better understanding of the plaque type specific material properties. With this understanding, biomechanical plaque modeling may eventually provide essential support for clinical plaque risk stratification. Copyright © 2014 Elsevier Ltd. All rights reserved.

[Presence of pre-Columbian maize in the Old World--an overview].

PubMed

Uchibayashi, Masao

2006-06-01

An overview is presented on the reports available so far on pre-Columbian maize covering the regions of India, Mideast, Africa and Iberia. Frequent observations of maize recorded in the past on the East and the West Coast of Africa and at the ports in the Mideast show that maize was one of the staples of the natives well before 1492. It is also evident that maize in the West Africa was disseminated to Iberia and Lombardy in the pre-Columbian time. An earlier contact between the Old and the New World is strongly suggested.

Bioinspired Principles for Large-Scale Networked Sensor Systems: An Overview

PubMed Central

Jacobsen, Rune Hylsberg; Zhang, Qi; Toftegaard, Thomas Skjødeberg

2011-01-01

Biology has often been used as a source of inspiration in computer science and engineering. Bioinspired principles have found their way into network node design and research due to the appealing analogies between biological systems and large networks of small sensors. This paper provides an overview of bioinspired principles and methods such as swarm intelligence, natural time synchronization, artificial immune system and intercellular information exchange applicable for sensor network design. Bioinspired principles and methods are discussed in the context of routing, clustering, time synchronization, optimal node deployment, localization and security and privacy. PMID:22163841

Bioinspired principles for large-scale networked sensor systems: an overview.

PubMed

Jacobsen, Rune Hylsberg; Zhang, Qi; Toftegaard, Thomas Skjødeberg

2011-01-01

Biology has often been used as a source of inspiration in computer science and engineering. Bioinspired principles have found their way into network node design and research due to the appealing analogies between biological systems and large networks of small sensors. This paper provides an overview of bioinspired principles and methods such as swarm intelligence, natural time synchronization, artificial immune system and intercellular information exchange applicable for sensor network design. Bioinspired principles and methods are discussed in the context of routing, clustering, time synchronization, optimal node deployment, localization and security and privacy.

Employee assistance programs: an overview and suggested roles for psychiatrists.

PubMed

Brill, P; Herzberg, J; Speller, J L

1985-07-01

Although employee assistance programs are rapidly becoming the predominant vehicle for the delivery of mental health services in occupational settings, few programs employ a psychiatrist on either a part-time or a full-time basis. After providing an overview of the need for, cost-effectiveness of, and current status of employee assistance programs, the authors draw on their own experiences with employee assistance programs to present four broad categories of roles the psychiatrist can assume in such programs: clinician, supervisor and educator, administrator, and organizational consultant. Problems encountered in these roles are also discussed.

The Publishing of Library and Information Science Journals in Southeast Asia--An Overview.

ERIC Educational Resources Information Center

Yeow-fei, Jaffe Yee

This paper presents an overview of the present state of the publishing activities of library and information science journals in Southeast Asia, focusing on format, circulation/readership, quality, and editorial focus. It also highlights some of the important titles from Thailand, Malaysia, Singapore, the Philippines, Indonesia, Brunei, Vietnam,…

DSM-III: the major achievements and an overview.

PubMed

Spitzer, R L; Williams, J B; Skodol, A E

1980-02-01

DSM-III will be published early this year. In the first part of this article the authors describe some of the major achievements of DSM-III: the process of its development, reaching consensus on many controversial diagnostic categories and a definition of mental disorder, the provision of diagnostic criteria and a multiaxial evaluation system, and the demonstration of improved diagnostic reliability. In the second part of the article the authors present an overview of DSM-III in which they describe its departures from DSM-II and the reasons for these changes. They conclude that in the next few years there should be systematic study of DSM-III in use, so that information about its strengths and limitations can be made available to those responsible for developing DSM-IV.

Progression in attenuating myocardial reperfusion injury: an overview.

PubMed

Bernink, F J P; Timmers, L; Beek, A M; Diamant, M; Roos, S T; Van Rossum, A C; Appelman, Y

2014-01-01

Reperfusion by means of percutaneous coronary intervention or thrombolytic therapy is the most effective treatment for acute myocardial infarction, markedly reducing mortality and morbidity. Reperfusion however induces necrotic and apoptotic damages to cardiomyocytes, that were viable prior to reperfusion, a process called lethal reperfusion injury. This process, consisting of many single processes, may be responsible of up to half of the final infarct size. A myriad of therapies as an adjunct to reperfusion have been studied with the purpose to attenuate reperfusion injury. The majority of these studies have been disappointing or contradicting, but recent proof-of-concept trials show that reperfusion injury still is a legitimate target. This overview will discuss these trials, the progression in attenuating myocardial reperfusion injury, promising therapies, and future perspectives. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

An overview of health control in Croatian aquaculture.

PubMed

Oraić, D; Zrncić, S

2005-08-01

Aquaculture is an important segment of Croatian fishing industry with long tradition of carp and rainbow trout farming as well as marine aquaculture represented by shellfish (flat oyster and mussels), sea bass and sea bream cultivation and Atlantic bluefin tuna fattening. The fish and shellfish diseases survey is regulated by "Decree on the measures of animal health protection against infectious and parasite diseases" issued yearly by Ministry of Agriculture. This report derives from systematic clinical, parasitological, pathoanatomical, histopathological, bacteriological and virological monitoring of cultivated fish and shellfish on larger part of production during last several years. Among pathological conditions recognised on our farms, some specific viruses, bacteria and parasites represent frequently established causative nosologic agents. The overview of the main diseases with economic impact to the cultivation will be discussed in this paper.

Overview of Materials Qualification Needs for Metal Additive Manufacturing

NASA Astrophysics Data System (ADS)

Seifi, Mohsen; Salem, Ayman; Beuth, Jack; Harrysson, Ola; Lewandowski, John J.

2016-03-01

This overview highlights some of the key aspects regarding materials qualification needs across the additive manufacturing (AM) spectrum. AM technology has experienced considerable publicity and growth in the past few years with many successful insertions for non-mission-critical applications. However, to meet the full potential that AM has to offer, especially for flight-critical components (e.g., rotating parts, fracture-critical parts, etc.), qualification and certification efforts are necessary. While development of qualification standards will address some of these needs, this overview outlines some of the other key areas that will need to be considered in the qualification path, including various process-, microstructure-, and fracture-modeling activities in addition to integrating these with lifing activities targeting specific components. Ongoing work in the Advanced Manufacturing and Mechanical Reliability Center at Case Western Reserve University is focusing on fracture and fatigue testing to rapidly assess critical mechanical properties of some titanium alloys before and after post-processing, in addition to conducting nondestructive testing/evaluation using micro-computerized tomography at General Electric. Process mapping studies are being conducted at Carnegie Mellon University while large area microstructure characterization and informatics (EBSD and BSE) analyses are being conducted at Materials Resources LLC to enable future integration of these efforts via an Integrated Computational Materials Engineering approach to AM. Possible future pathways for materials qualification are provided.

An overview of the National Space Science data Center Standard Information Retrieval System (SIRS)

NASA Technical Reports Server (NTRS)

Shapiro, A.; Blecher, S.; Verson, E. E.; King, M. L. (Editor)

1974-01-01

A general overview is given of the National Space Science Data Center (NSSDC) Standard Information Retrieval System. A description, in general terms, the information system that contains the data files and the software system that processes and manipulates the files maintained at the Data Center. Emphasis is placed on providing users with an overview of the capabilities and uses of the NSSDC Standard Information Retrieval System (SIRS). Examples given are taken from the files at the Data Center. Detailed information about NSSDC data files is documented in a set of File Users Guides, with one user's guide prepared for each file processed by SIRS. Detailed information about SIRS is presented in the SIRS Users Guide.

Overview of reviews: mechanical interventions for the treatment and management of chronic obstructive pulmonary disease.

PubMed

Lisy, Karolina; White, Heath; Pearson, Alan

2014-12-01

Chronic obstructive pulmonary disease (COPD) is characterized by a progressive and non-reversible airflow limitation and symptoms of breathlessness, sputum production and cough. COPD is the fourth most common cause of mortality worldwide and represents a significant social and economic burden. As such, effective strategies that might be employed to treat COPD and manage symptoms need to be investigated. This overview aimed to summarize the existing evidence available in the Cochrane Library regarding the use of mechanical interventions used for the treatment and management of COPD. Systematic reviews that included adult participants with diagnosed COPD who received a mechanical intervention were included. Five reviews were included, and due to the heterogeneity of these reviews, direct and indirect comparisons of the effects of the intervention were not possible. Instead, data of the effectiveness of each intervention were extracted and summarized in tables and discussed as a narrative summary. Interventions included non-invasive positive pressure ventilation (NPPV), positive airway pressure (PEP) devices and neuromuscular electrical stimulation (NMES). Evidence regarding the effectiveness of NPPV was limited, and available data do not support the use of NPPV for patients with stable COPD. NPPV might, however, be of benefit as a weaning strategy for intubated patients and for patients experiencing respiratory failure; however, more research is required. Although PEP devices are considered as a safe airway clearance technique, data do not reveal a clear clinical benefit to their use. NMES is also regarded as safe for patients with COPD, and might also be beneficial in improving exercise tolerance and improving quality of life for patients with COPD. © 2014 Wiley Publishing Asia Pty Ltd.

Population biology of the Florida manatee: An overview

USGS Publications Warehouse

O'Shea, Thomas J.; Ackerman, B.B.; O'Shea, Thomas J.; Ackerman, B.B.; Percival, H. Franklin

1995-01-01

In the following overview we discuss progress toward meeting the three objectives of the 1992 workshop: to provide a synthesis of existing information about manatee population biology; to evaluate the strengths and weaknesses of current data sets and approaches to research on manatee population biology; and to provide recommendations for research. We discuss progress in six topics that were assigned to working groups at the workshop: aerial survey and estimation of population size, reproduction, age structure, mortality, photoidentification and estimation of survival, and integration and modeling of population data. The overview includes recommendations by working group participants (*2 0'Shea et al. 1992). This workshop on manatee population biology was the most recent conference on the topic since 1978 (*BrowneIl and Rails 1981). Partly as a result of recommendations made at the 1978 workshop, several long-term population-related research projects were established. Therefore, we also measure progress in relation to knowledge available at the time of the earlier workshop. Finally, we provide a brief synopsis of pertinent new information on manatee population biology that became available between the 1992 workshop and publication of the proceedings and our conclusions about the status of the Florida manatee.

Absorption of Solar Radiation by Clouds: An Overview

NASA Technical Reports Server (NTRS)

Tsay, Si-Chee; Einaudi, Franco (Technical Monitor)

2000-01-01

This talk provides an overview of the subject of absorption of solar radiation by clouds in the earth's atmosphere. The paper summarizes the available evidence which points to disagreements between theoretical and observed values of cloud absorption (and reflections). The importance of these discrepancies, particularly to remote sensing of clouds as well as to studies of cloud physics and earth radiation budgets, is emphasized. Existing cloud absorption and reflection measurements are reviewed and the persistent differences that exist between calculated and measured near-infrared cloud albedos are highlighted. Various explanations for these reflection and absorption discrepancies are discussed under two separate paths: a theoretician's approach and an experimentalist's approach. Examples for the former approach include model accuracy tests, large-droplet hypothesis, excess absorbing aerosol, enhanced water vapor continuum absorption, and effects of cloud inhomogeneity. The latter approach focuses on discussions of instrumental device, calibration, operational strategy, and signal/noise separation. A recommendation for future activities on this subject will be given.

Overview on mechanisms of acetic acid resistance in acetic acid bacteria.

PubMed

Wang, Bin; Shao, Yanchun; Chen, Fusheng

2015-02-01

Acetic acid bacteria (AAB) are a group of gram-negative or gram-variable bacteria which possess an obligate aerobic property with oxygen as the terminal electron acceptor, meanwhile transform ethanol and sugar to corresponding aldehydes, ketones and organic acids. Since the first genus Acetobacter of AAB was established in 1898, 16 AAB genera have been recorded so far. As the main producer of a world-wide condiment, vinegar, AAB have evolved an elegant adaptive system that enables them to survive and produce a high concentration of acetic acid. Some researches and reviews focused on mechanisms of acid resistance in enteric bacteria and made the mechanisms thoroughly understood, while a few investigations did in AAB. As the related technologies with proteome, transcriptome and genome were rapidly developed and applied to AAB research, some plausible mechanisms conferring acetic acid resistance in some AAB strains have been published. In this review, the related mechanisms of AAB against acetic acid with acetic acid assimilation, transportation systems, cell morphology and membrane compositions, adaptation response, and fermentation conditions will be described. Finally, a framework for future research for anti-acid AAB will be provided.

The Hispanic family and male-female relationships: an overview.

PubMed

Galanti, Geri-Ann

2003-07-01

An overview of the traditional Hispanic family and male-female relationships is presented, with an emphasis on issues relevant to providing health care to Hispanic populations. Aspects of the family presented include visitation, decision making, self-care, and emotional problems. Male-female relationships stem from traditional gender roles. Machismo and patriarchal authority characterize the male role; the roles of a traditional woman are housewife and mother. Women are expected to defer to the authority of their husbands. The negative aspects of machismo can result in heavy drinking and the pursuit of high-risk activities, leading to domestic violence and HIV/AIDS. These health risks are exacerbated by such cultural factors as male dominance, female modesty, and the practice of keeping problems within the family. The importance of personalism in patient-provider encounters is emphasized.

Artificial humidification for the mechanically ventilated patient.

PubMed

Selvaraj, N

Caring for patients who are mechanically ventilated poses many challenges for critical care nurses. It is important to humidify the patient's airways artificially to prevent complications such as ventilator-associated pneumonia. There is no gold standard to determine which type of humidification is best for patients who are artificially ventilated. This article provides an overview of commonly used artificial humidification for mechanically ventilated patients and discusses nurses' responsibilities in caring for patients receiving artificial humidification.

An overview of the phase-modular fault tree approach to phased mission system analysis

NASA Technical Reports Server (NTRS)

Meshkat, L.; Xing, L.; Donohue, S. K.; Ou, Y.

2003-01-01

We look at how fault tree analysis (FTA), a primary means of performing reliability analysis of PMS, can meet this challenge in this paper by presenting an overview of the modular approach to solving fault trees that represent PMS.

Living Cell Microarrays: An Overview of Concepts

PubMed Central

Jonczyk, Rebecca; Kurth, Tracy; Lavrentieva, Antonina; Walter, Johanna-Gabriela; Scheper, Thomas; Stahl, Frank

2016-01-01

Living cell microarrays are a highly efficient cellular screening system. Due to the low number of cells required per spot, cell microarrays enable the use of primary and stem cells and provide resolution close to the single-cell level. Apart from a variety of conventional static designs, microfluidic microarray systems have also been established. An alternative format is a microarray consisting of three-dimensional cell constructs ranging from cell spheroids to cells encapsulated in hydrogel. These systems provide an in vivo-like microenvironment and are preferably used for the investigation of cellular physiology, cytotoxicity, and drug screening. Thus, many different high-tech microarray platforms are currently available. Disadvantages of many systems include their high cost, the requirement of specialized equipment for their manufacture, and the poor comparability of results between different platforms. In this article, we provide an overview of static, microfluidic, and 3D cell microarrays. In addition, we describe a simple method for the printing of living cell microarrays on modified microscope glass slides using standard DNA microarray equipment available in most laboratories. Applications in research and diagnostics are discussed, e.g., the selective and sensitive detection of biomarkers. Finally, we highlight current limitations and the future prospects of living cell microarrays. PMID:27600077

Minerals in thalassaemia major patients: An overview.

PubMed

Ozturk, Zeynep; Genc, Gizem Esra; Gumuslu, Saadet

2017-05-01

Thalassaemia major (TM) is a hereditary blood disease characterised by reduced or absent production of beta globin chains. Erythrocyte transfusions are given to raise the haemoglobin level in patients with thalassaemia major. However, transfusions have been related to increased risk of iron overload and tissue damage related to excess iron. Both elevated oxidative stress due to iron overload and increased hemolysis lead to over utilisation of minerals required for antioxidant enzymes activities. Iron chelators have been used to prevent iron overload in thalassaemia major patients, but these chelators have the possibility of removing minerals from the body. Thalassaemia patients are more at risk for mineral deficiency because of increased oxidative stress and iron chelation therapies. Growth and maturational delay, cardiomyopathy, endocrinopathies and osteoporosis are the complications of thalassaemia. Minerals may play a particular role to prevent these complications. In the current review, we provide an overview of minerals including zinc (Zn), copper (Cu), selenium (Se), magnesium (Mg) and calcium (Ca) in thalassaemia major patients. We, also, underline that some complications of thalassaemia can be caused by an increased need for minerals or lack of the minerals. Copyright © 2017 Elsevier GmbH. All rights reserved.

Factors affecting physicians' use of a dedicated overview interface in an electronic health record: The importance of standard information and standard documentation.

PubMed

Jensen, Lotte Groth; Bossen, Claus

2016-03-01

It remains a continual challenge to present information in user interfaces in large IT systems to support overview in the best possible way. We here examine how an electronic health record (EHR) supports the creation of overview among hospital physicians with a particular focus on the use of an interface designed to provide clinicians with a patient information overview. The overview interface integrates information flexibly from diverse places in the EHR and presents this information in one screen display. Our study revealed widespread non-use of the overview interface. We explore the reasons for its use and non-use. We conducted exploratory ethnographic fieldwork among physicians in two hospitals and gathered statistical data on their use of the overview interface. From the quantitative data, we identified where the interface was used most and conducted 18 semi-structured, open-ended interviews framed by the theoretical framework and the findings of the initial ethnographic fieldwork. We interviewed both physicians and employees from the IT units in different hospitals. We then analysed notes from the ethnographic fieldwork and the interviews and ordered these into themes forming the basis for the presentation of findings. The overview interface was most used in departments or situations where the problem at hand and the need for information could be standardized-in particular, in anesthesiological departments and outpatient clinics. However, departments with complex and long patient histories did not make much use of the overview interface. Design and layout were not mentioned as decisive factors affecting its use or non-use. Many physicians questioned the completeness of data in the overview interface-either because they were skeptical about the hospital's or the department's documentation practices, or because they could not recognize the structure of the interface. This uncertainty discouraged physicians from using the overview interface. Dedicating a

Interventions for the prevention of OHSS in ART cycles: an overview of Cochrane reviews.

PubMed

Mourad, Selma; Brown, Julie; Farquhar, Cindy

2017-01-23

Ovarian hyperstimulation syndrome (OHSS) in assisted reproductive technology (ART) cycles is a treatment-induced disease that has an estimated prevalence of 20% to 33% in its mild form and 3% to 8% in its moderate or severe form. These numbers might even be higher for high-risk women such as those with polycystic ovaries or a high oocyte yield from ovum pickup. The objective of this overview is to identify and summarise all evidence from Cochrane systematic reviews on interventions for prevention or treatment of moderate, severe and overall OHSS in couples with subfertility who are undergoing ART cycles. Published Cochrane systematic reviews reporting on moderate, severe or overall OHSS as an outcome in ART cycles were eligible for inclusion in this overview. We also identified Cochrane submitted protocols and title registrations for future inclusion in the overview. The evidence is current to 12 December 2016. We identified reviews, protocols and titles by searching the Cochrane Gynaecology and Fertility Group Database of Systematic Reviews and Archie (the Cochrane information management system) in July 2016 on the effectiveness of interventions for outcomes of moderate, severe and overall OHSS. We undertook in duplicate selection of systematic reviews, data extraction and quality assessment. We used the AMSTAR (Assessing the Methodological Quality of Systematic Reviews) tool to assess the quality of included reviews, and we used GRADE methods to assess the quality of the evidence for each outcome. We summarised the characteristics of included reviews in the text and in additional tables. We included a total of 27 reviews in this overview. The reviews were generally of high quality according to AMSTAR ratings, and included studies provided evidence that ranged from very low to high in quality. Ten reviews had not been updated in the past three years. Seven reviews described interventions that provided a beneficial effect in reducing OHSS rates, and we categorised

SEWER SEDIMENT CONTROL: AN OVERVIEW OF THE EPA WET WEATHER FLOW (WWF) RESEARCH PROGRAM

EPA Science Inventory

This paper presents an overview of EPA WWF Research Program projects related to causes of sewer solids deposition and control methods that can prevent accumulation of sewer sediments. In particular, discussion will focus on the relationship of wastewater characteristics to flow ...

Endometriosis: an overview of Cochrane Reviews.

PubMed

Brown, Julie; Farquhar, Cindy

2014-03-10

This overview reports on interventions for pain relief and for subfertility in pre-menopausal women with clinically diagnosed endometriosis. The objective of this overview was to summarise the evidence from Cochrane systematic reviews on treatment options for women with pain or subfertility associated with endometriosis. Published Cochrane systematic reviews reporting pain or fertility outcomes in women with clinically diagnosed endometriosis were eligible for inclusion in the overview. We also identified Cochrane reviews in preparation (protocols and titles) for future inclusion. The reviews, protocols and titles were identified by searching the Cochrane Database of Systematic Reviews and Archie (the Cochrane information management system) in March 2014.Pain-related outcomes of the overview were pain relief, clinical improvement or resolution and pain recurrence. Fertility-related outcomes were live birth, clinical pregnancy, ongoing pregnancy, miscarriage and adverse events.Selection of systematic reviews, data extraction and quality assessment were undertaken in duplicate. Review quality was assessed using the AMSTAR tool. The quality of the evidence for each outcome was assessed using GRADE methods. Review findings were summarised in the text and the data for each outcome were reported in 'Additional tables'. Seventeen systematic reviews published in The Cochrane Library were included. All the reviews were high quality. The quality of the evidence for specific comparisons ranged from very low to moderate. Limitations in the evidence included risk of bias in the primary studies, inconsistency between the studies, and imprecision in effect estimates. Pain relief (14 reviews) Gonadotrophin-releasing hormone (GnRH) analogues One systematic review reported low quality evidence of an overall benefit for GnRH analogues compared with placebo or no treatment. Ovulation suppression Five systematic reviews reported on medical treatment using ovulation suppression. There

Overview of the ACT program

NASA Technical Reports Server (NTRS)

Davis, John G., Jr.

1992-01-01

NASA's Advanced Composites Program (ACT) was initiated in 1988. A National Research Announcement was issued to solicit innovative ideas that could significantly contribute to development and demonstration of an integrated technology data base and confidence level that permits cost-effective use of composite primary structures in transport aircraft. Fifteen contracts were awarded by the Spring of 1989 and the participants include commercial and military airframe manufacturers, materials developers and suppliers, universities, and government laboratories. The program approach is to develop materials, structural mechanics methodology, design concepts, and fabrication procedures that offer the potential to make composite structures cost-effective compared to aluminum structure. Goals for the ACT program included 30-50 percent weight reduction, 20-25 percent acquisition cost reduction, and provided the scientific basis for predicting materials and structures performance. This paper provides an overview of the ACT program status, plans, and selected technical accomplishments. Sixteen additional papers, which provide more detailed information on the research and development accomplishments, are contained in this publication.

ISRU: An Overview of NASA'S Current Development Activities and Long-Term Goals

NASA Technical Reports Server (NTRS)

Sanders, Gerald B.; Nicholson, Leonard S. (Technical Monitor)

2000-01-01

The concept of "living off the land" by utilizing the indigenous resources of the Moon, Mars, or other potential sites of robotic and human exploration has been termed In-Situ Resource Utilization (ISRU). It is fundamental to any program of extended human presence and operation on other extraterrestrial bodies that we learn how to utilize the indigenous resources. The chief benefits of ISRU are that it can reduce the mass, cost, and risk of robotic and human exploration while providing capabilities that enable the commercial development of space. In January 1997, the American Institute of Aeronautics and Astronautics (AIAA) Space Processing Technical Committee released a position paper entitled, "Need for A NASA Indigenous Space Resource Utilization (ISRU) Program". Besides outlining some of the potential advantages of incorporating ISRU into Lunar and Mars human mission plans and providing an overview of technologies and processes of interest, the position paper concluded with a list of seven recommendations to NASA. This paper will examine the seven recommendations proposed and provide an overview of NASA's current ISRU development activities and possible long term goals with respect to these recommendations.

Blood pressure and stroke: an overview of published reviews.

PubMed

Lawes, Carlene M M; Bennett, Derrick A; Feigin, Valery L; Rodgers, Anthony

2004-03-01

The last few years have seen a considerable increase in the amount of information available concerning blood pressure (BP) and stroke associations. This article provides an overview of published reviews of the effects on stroke seen in trials of BP-lowering drugs and compares these with the results available from cohort studies. We present a review of major overviews of prospective cohort studies and an updated meta-analysis of >40 randomized controlled trials of BP lowering, which included >188 000 participants and approximately 6800 stroke events. Cohort studies now indicate that in the Asia Pacific region as well as in North America and Western Europe, each 10 mm Hg lower systolic BP is associated with a decrease in risk of approximately one third in subjects aged 60 to 79 years. The association is continuous down to levels of at least 115/75 mm Hg and is consistent across sexes, regions, and stroke subtypes and for fatal and nonfatal events. The proportional association is age dependent but is still a strong and positive association in those aged 80 years. Data from randomized controlled trials, in which mean age at event was approximately 70 years, indicate that a 10 mm Hg reduction in systolic BP is associated with a reduction in risk of stroke of approximately one third. Per mm Hg systolic BP reduction, the benefits for stroke appear similar between agents, by baseline BP levels, and whether or not individuals have a past history of cardiovascular disease. There is, however, evidence of greater benefit with a larger BP reduction. The epidemiologically expected benefits of BP lowering for stroke risk reduction are broadly consistent across a range of different population subgroups. There are greater benefits from larger BP reductions, and initiating and maintaining BP reduction for stroke prevention is a more important issue than choice of initial agent.

Blood pressure and stroke: an overview of published reviews.

PubMed

Lawes, Carlene M M; Bennett, Derrick A; Feigin, Valery L; Rodgers, Anthony

2004-04-01

The last few years have seen a considerable increase in the amount of information available concerning blood pressure (BP) and stroke associations. This article provides an overview of published reviews of the effects on stroke seen in trials of BP-lowering drugs and compares these with the results available from cohort studies. We present a review of major overviews of prospective cohort studies and an updated meta-analysis of >40 randomized controlled trials of BP lowering, which included >188 000 participants and approximately 6800 stroke events. Cohort studies now indicate that in the Asia Pacific region as well as in North America and Western Europe, each 10 mm Hg lower systolic BP is associated with a decrease in risk of stroke of approximately one third in subjects aged 60 to 79 years. The association is continuous down to levels of at least 115/75 mm Hg and is consistent across sexes, regions, and stroke subtypes and for fatal and nonfatal events. The proportional association is age dependent but is still strong and positive in those aged 80 years. Data from randomized controlled trials, in which mean age at event was approximately 70 years, indicate that a 10 mm Hg reduction in systolic BP is associated with a reduction in risk of stroke of approximately one third. Per mm Hg systolic BP reduction, the relative benefits for stroke appear similar between agents, by baseline BP levels, and whether or not individuals have a past history of cardiovascular disease. There is, however, evidence of greater benefit with a larger BP reduction. The epidemiologically expected benefits of BP lowering for stroke risk reduction are broadly consistent across a range of different population subgroups. There are greater benefits from larger BP reductions, and initiating and maintaining BP reduction for stroke prevention is a more important issue than choice of initial agent.

An Overview of the Current Status of Talent Care and Talent Support in Hungary

ERIC Educational Resources Information Center

Fuszek, Csilla

2014-01-01

After a short historical introduction, the article provides an overview of the current talent support trends in Hungary. It gives an insight into the legislation, guidelines and institutional system associated with the national talent support strategy, and presents the main NGO initiatives present in the early 21st century, in particular the…

Er:YAG lasers in dentistry: an overview

NASA Astrophysics Data System (ADS)

Rechmann, Peter; Goldin, Dan S.; Hennig, Thomas

1998-04-01

Aim of this presentation is to review the role of the Er:YAG laser in dentistry and to give a general overview on the work done with it up to date. A look at the development and evolution of this system is given as well as a brief introduction into the basic principles of ablation at the characteristic wavelength 2.94 micrometer. The more important research reports of the different groups all over the world are summarized and the large field of applications such as cavity preparation, caries ablation, periodontology and bacterial reduction is considered.

Conducting a Southern Pine Beetle Survey Using Digital Aerial Sketchmapping (DASM) - An Overview

Treesearch

Chris A. Steiner

2011-01-01

This is an overview on conducting a southern pine beetle (SPB) survey using Digital Aerial Sketchmapping (DASM); for a detailed treatment of DASM visit the following Web site: http://www.fs.fed.us/foresthealth/ technology/dasm.shtml. Sketchmapping – “A remote sensing technique of observing forest change events from an aircraft and documenting them manually on a map” (...

Mechanical and chemical recycling of solid plastic waste.

PubMed

Ragaert, Kim; Delva, Laurens; Van Geem, Kevin

2017-11-01

This review presents a comprehensive description of the current pathways for recycling of polymers, via both mechanical and chemical recycling. The principles of these recycling pathways are framed against current-day industrial reality, by discussing predominant industrial technologies, design strategies and recycling examples of specific waste streams. Starting with an overview on types of solid plastic waste (SPW) and their origins, the manuscript continues with a discussion on the different valorisation options for SPW. The section on mechanical recycling contains an overview of current sorting technologies, specific challenges for mechanical recycling such as thermo-mechanical or lifetime degradation and the immiscibility of polymer blends. It also includes some industrial examples such as polyethylene terephthalate (PET) recycling, and SPW from post-consumer packaging, end-of-life vehicles or electr(on)ic devices. A separate section is dedicated to the relationship between design and recycling, emphasizing the role of concepts such as Design from Recycling. The section on chemical recycling collects a state-of-the-art on techniques such as chemolysis, pyrolysis, fluid catalytic cracking, hydrogen techniques and gasification. Additionally, this review discusses the main challenges (and some potential remedies) to these recycling strategies and ground them in the relevant polymer science, thus providing an academic angle as well as an applied one. Copyright © 2017 Elsevier Ltd. All rights reserved.

The State of Agricultural Extension: An Overview and New Caveats for the Future

ERIC Educational Resources Information Center

Benson, Amanda; Jafry, Tahseen

2013-01-01

Purpose: This review paper presents an overview of changes in agricultural extension on a global scale and helps to characterise on-going developments in extension practice. Design/methodology/approach: Through a critique and synthesis of literature the paper focuses on global political changes which have led to widespread changes from production-…

An overview of underwater remotely manned Systems and sub-systems

NASA Technical Reports Server (NTRS)

Rechnitzer, A., B.

1975-01-01

A current overview of how the underwater facet of remotely manned systems has progressed since 1972 is presented. The current approaches being pursued and the success of American and foreign technology is assessed.

The male reproductive system - An overview of common problems.

PubMed

Wijesinha, Sanjiva; Piterman, Leon; Kirby, Catherine N

2013-05-01

Many male reproductive system problems could be perceived as being embarrassing, which may be one of the reasons that they are often not identified in general practice. This article provides an overview of some common problems affecting the male reproductive system, and outlines current treatment options. Erectile dysfunction, premature ejaculation, loss of libido, testicular cancer and prostate disease may cause embarrassment to the patient and, occasionally, the general practitioner. We describe how patients affected by these conditions may present to general practice, and discuss the reasons why they may not present. We also discuss how GPs can overcome difficulties in identifying and dealing with their male patients suffering from male reproductive system issues.

Male infertility: an overview of causes and treatment options.

PubMed

Leaver, Rachel Busuttil

2016-10-13

It is estimated that 3.5 million people in the UK, that is one in every seven couples, have fertility problems. In the past, it was assumed that the cause always lay with the woman. However, developments in science brought a greater understanding of the process of sperm production and conception. It is now known that up to 30% of fertility problems may be because of the man alone and up to 90% of these are down to low sperm count or low sperm quality or both. This paper offers a review of the causes and potential factors that affect male fertility together with an overview of diagnosis, investigation and current treatment options for these men.

An overview of the endodontic curriculum in Fiji from 2009 to 2013.

PubMed

Devi, Arpana A; Abbott, Paul V

2015-12-01

This paper seeks to provide the reader with an overview of the endodontic curriculum in Fiji from 2009 to 2013. It also intends to inform readers of the changes in endodontic teaching, the learning methods utilised, curriculum development, the transition from block teaching to partial block teaching combined with longitudinal teaching, and the future plans for the endodontic module. © 2015 Australian Society of Endodontology.

Introducing the LHC in the classroom: an overview of education resources available

NASA Astrophysics Data System (ADS)

Wiener, Gerfried J.; Woithe, Julia; Brown, Alexander; Jende, Konrad

2016-05-01

In the context of the recent re-start of CERN’s Large Hadron Collider (LHC) and the challenge presented by unidentified falling objects (UFOs), we seek to facilitate the introduction of high energy physics in the classroom. Therefore, this paper provides an overview of the LHC and its operation, highlighting existing education resources, and linking principal components of the LHC to topics in physics curricula.

Lunar Reconnaissance Orbiter (LRO) Navigation Overview

NASA Technical Reports Server (NTRS)

Lamb, Rivers

2008-01-01

This viewgraph presentation is an overview of the Lunar Reconnaissance Orbiter (LRO), with emphasis on the navigation and plans for the mission. The objective of the LRO mission is to conduct investigations that will be specifically target to prepare for and support future human exploration of the Moon. There is a review of the scientific instruments on board the LRO and an overview of the phases of the planned trajectory.

An overview of the quiet short-haul research aircraft program

NASA Technical Reports Server (NTRS)

Shovlin, M. D.; Cochrane, J. A.

1978-01-01

An overview of the Quiet Short Haul Research Aircraft (QSRA) Program is presented, with special emphasis on its propulsion and acoustic aspects. A description of the NASA technical participation in the program including wind tunnel testing, engine ground tests, and advanced aircraft simulation is given. The aircraft and its systems are described and, measured performance, where available, is compared to program goals. Preliminary data indicate that additional research and development are needed in some areas of which acoustics is an example. Some of these additional research areas and potential experiments using the QSRA to develop the technology are discussed. The concept of the QSRA as a national flight research facility is explained.

Chiral Drug Analysis in Forensic Chemistry: An Overview.

PubMed

Ribeiro, Cláudia; Santos, Cristiana; Gonçalves, Valter; Ramos, Ana; Afonso, Carlos; Tiritan, Maria Elizabeth

2018-01-28

Many substances of forensic interest are chiral and available either as racemates or pure enantiomers. Application of chiral analysis in biological samples can be useful for the determination of legal or illicit drugs consumption or interpretation of unexpected toxicological effects. Chiral substances can also be found in environmental samples and revealed to be useful for determination of community drug usage (sewage epidemiology), identification of illicit drug manufacturing locations, illegal discharge of sewage and in environmental risk assessment. Thus, the purpose of this paper is to provide an overview of the application of chiral analysis in biological and environmental samples and their relevance in the forensic field. Most frequently analytical methods used to quantify the enantiomers are liquid and gas chromatography using both indirect, with enantiomerically pure derivatizing reagents, and direct methods recurring to chiral stationary phases.

Overview of NASA GRC's Efforts In SWBLI

NASA Technical Reports Server (NTRS)

Long-Davis, Mary Jo

2017-01-01

Overview of NASA Efforts (related to SWBLI research) An overview of NASA's restructured ARMD Program and the resulting new projects. Areas of research pertaining to shock wave boundary layer interaction are highlighted. Plans and status for specific tasks are presented.

An overview of results derived from mobile-satellite propagation experiments

NASA Technical Reports Server (NTRS)

Goldhirsh, Julius; Vogel, Wolfhard J.

1990-01-01

During the period 1983-1988, a series of Land Mobile Satellite Service (LMSS) propagation experiments were performed. These experiments were implemented with transmitters on stratospheric balloons, remotely piloted aircraft, helicopters, and geostationary satellites. The earlier experiments were performed at UHF (870 mega-Hz) and the latter at both L band (1.5 giga-Hz) and UHF. The general objective of the above tests was to assess the impairment to propagation caused by trees and terrain for predominantly suburban and rural regions where cellular communication services are impractical. This paper presents an overview of the results derived from the above experiments.

An overview of the dynamic calibration of piezoelectric pressure transducers

NASA Astrophysics Data System (ADS)

Theodoro, F. R. F.; Reis, M. L. C. C.; d’ Souto, C.

2018-03-01

Dynamic calibration is a research area that is still under development and is of great interest to aerospace and automotive industries. This study discusses some concepts regarding dynamic measurements of pressure quantities and presents an overview of dynamic calibration of pressure transducers. Studies conducted by the Institute of Aeronautics and Space focusing on research regarding piezoelectric pressure transducer calibration in shock tube are presented. We employed the Guide to the Expression of Uncertainty and a Monte Carlo Method in the methodology. The results show that both device and methodology employed are adequate to calibrate the piezoelectric sensor.

Adhesive Bonding to Hybrid Materials: An Overview of Materials and Recommendations.

PubMed

Spitznagel, Frank A; Vuck, Alexander; Gierthmühlen, Petra C; Blatz, Markus B; Horvath, Sebastian D

2016-10-01

Recently, hybrid materials have been introduced to the dental market. Together with computer-assisted design/computer-assisted manufacturing (CAD/CAM) composite resins, they form a new class of dental CAD/CAM materials that combine the positive effects of ceramics and composites. As bonding is essential for their clinical longevity, it is crucial to have a good understanding of their material properties and cementation protocols. This review offers clinicians an overview of available hybrid materials and recommendations for their respective adhesive placements.

1. OVERVIEW LOOKING EAST: overview taken from south end BLDG. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. OVERVIEW LOOKING EAST: overview taken from south end BLDG. 1. - Fafnir Bearing Plant, Bounded on North side by Myrtle Street, on South side by Orange Street, on East side by Booth Street & on West side by Grove Street, New Britain, Hartford County, CT

Epoxide hydrolases: structure, function, mechanism, and assay.

PubMed

Arand, Michael; Cronin, Annette; Adamska, Magdalena; Oesch, Franz

2005-01-01

Epoxide hydrolases are a class of enzymes important in the detoxification of genotoxic compounds, as well as in the control of physiological signaling molecules. This chapter gives an overview on the function, structure, and enzymatic mechanism of structurally characterized epoxide hydrolases and describes selected assays for the quantification of epoxide hydrolase activity.

An overview of the Earth system science of solar geoengineering: Overview of the earth system science of solar geoengineering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Irvine, Peter J.; Kravitz, Ben; Lawrence, Mark G.

Solar geoengineering has been proposed as a means to cool the planet by increasing the reflection of sunlight back to space, for example by injecting reflective aerosol particles into the middle atmosphere. Such proposals are not able to physically substitute for mitigation of greenhouse gas emissions as a response to the risks of climate change, but might eventually be applied as a complementary approach to reduce climate risks. Thus, the Earth system consequences of solar geoengineering are central to understanding its potentials and risks. Here we review the state-of-the-art knowledge about geoengineering by stratospheric sulphate aerosol injection. We examine themore » common responses found in studies of an idealized form of solar geoengineering, in which the intensity of incoming sunlight is directly reduced in models. The studies reviewed are consistent in suggesting that solar geoengineering would generally reduce the differences in climate in comparison to future scenarios with elevated greenhouse gas concentrations and no solar geoengineering. However, it is clear that a solar geoengineered climate would be novel in some respects, for example a notable reduction in the intensity of the hydrological cycle. We provide an overview of the unique aspects of the response to stratospheric aerosol injection and the uncertainties around its consequences. We also consider the issues raised by the partial control over the climate that solar geoengineering would allow. Finally, this overview also highlights the key research gaps that will need to be resolved in order to effectively guide future decisions on the potential use of solar geoengineering.« less

Overview of multi-input frequency domain modal testing methods with an emphasis on sine testing

NASA Technical Reports Server (NTRS)

Rost, Robert W.; Brown, David L.

1988-01-01

An overview of the current state of the art multiple-input, multiple-output modal testing technology is discussed. A very brief review of the current time domain methods is given. A detailed review of frequency and spatial domain methods is presented with an emphasis on sine testing.

An epidemiological overview of malaria in Bangladesh.

PubMed

Islam, Nazrul; Bonovas, Stefanos; Nikolopoulos, Georgios K

2013-01-01

Bangladesh is one of the four major malaria-endemic countries in South-East Asia having approximately 34% of its population at risk of malaria. This paper aims at providing an overview of the malaria situation in this country. Relevant information was retrieved from published articles and reports in PubMed and Google Scholar. Malaria in Bangladesh is concentrated in 13 districts with a prevalence ranging between 3.1% and 36%, and is mostly caused by Plasmodium falciparum. Geographical conditions pose a potential risk for Plasmodium knowlesi malaria. Resistance to a number of drugs previously recommended for treatment has been reported. Low socio-economic status, poor schooling and close proximity to water bodies and forest areas comprise important risk factors. Despite the significant steps in Long Lasting Insecticide Net (LLIN)/Insecticide Treated Net (ITN) coverage in Bangladesh, there are still many challenges including the extension of malaria support to the remote areas of Bangladesh, where malaria prevalence is higher, and further improvements in the field of referral system and treatment. Copyright © 2013 Elsevier Ltd. All rights reserved.

The problem of active SETI: An overview

NASA Astrophysics Data System (ADS)

Musso, Paolo

2012-09-01

In the present paper (originally presented at the First IAA Symposium on Searching for Life Signatures hold at the UNESCO on 22-26 September 2008) I try to summarize the results of all my previous studies on active SETI and its possible dangers for us, also considering some new topics, in order to provide a possibly complete overview of the whole matter. First, I try to evaluate the possible risks of an indirect contact with aliens, from the social, cultural, and religious point of view; then, the possible risks related with receiving information about alien science and technology; finally, the risk that active SETI could increase the probability of a physical contact with hostile aliens. My conclusion is that active SETI is very unlikely to be dangerous for us, but, at present, such a possibility cannot be completely excluded. Surprisingly, it turns out that a very important point to be assessed in order to improve our evaluation of active SETI is the pace of our technological progress. Some suggestions about the policy that international community should adopt towards active SETI are also included.

Arsenic Hyperaccumulation Strategies: An Overview

PubMed Central

Souri, Zahra; Karimi, Naser; Sandalio, Luisa M.

2017-01-01

Arsenic (As) pollution, which is on the increase around the world, poses a growing threat to the environment. Phytoremediation, an important green technology, uses different strategies, including As uptake, transport, translocation, and detoxification, to remediate this metalloid. Arsenic hyperaccumulator plants have developed various strategies to accumulate and tolerate high concentrations of As. In these plants, the formation of AsIII complexes with GSH and phytochelatins and their transport into root and shoot vacuoles constitute important mechanisms for coping with As stress. The oxidative stress induced by reactive oxygen species (ROS) production is one of the principal toxic effects of As; moreover, the strong antioxidative defenses in hyperaccumulator plants could constitute an important As detoxification strategy. On the other hand, nitric oxide activates antioxidant enzyme and phytochelatins biosynthesis which enhances As stress tolerance in plants. Although several studies have focused on transcription, metabolomics, and proteomic changes in plants induced by As, the mechanisms involved in As transport, translocation, and detoxification in hyperaccumulator plants need to be studied in greater depth. This review updates recent progress made in the study of As uptake, translocation, chelation, and detoxification in As hyperaccumulator plants. PMID:28770198

Chemicals used in the rubber industry. An overview.

PubMed

Fishbein, L

1983-01-01

Hundreds of chemicals illustrative of many structural and use categories are employed in the rubber industry. The present overview has centered on the structural features of a number of compounds representative of several select use categories, eg, vulcanizing agents, accelerators, antioxidants, antiozonants, and blowing agents, with focus on the nature of their impurities, their chemical degradation, and by-products, as well as on those chemicals that can be converted to N-nitrosamines.

Computers in Education: An Overview. Publication Number One. Software Engineering/Education Cooperative Project.

ERIC Educational Resources Information Center

Collis, Betty; Muir, Walter

The first of four major sections in this report presents an overview of the background and evolution of computer applications to learning and teaching. It begins with the early attempts toward "automated teaching" of the 1920s, and the "teaching machines" of B. F. Skinner of the 1940s through the 1960s. It then traces the…

Strategic Investments Overview

NASA Technical Reports Server (NTRS)

Comstock, Doug

2004-01-01

This viewgraph presentation provides an overview of the organizational hierarchy for strategic management and strategic investments at NASA. The presentation also relates these topics to the budgets it submits to Congress, strategies for space exploration research and development, and systems analysis.

An overview of data integration methods for regional assessment.

PubMed

Locantore, Nicholas W; Tran, Liem T; O'Neill, Robert V; McKinnis, Peter W; Smith, Elizabeth R; O'Connell, Michael

2004-06-01

The U.S. Environmental Protections Agency's (U.S. EPA) Regional Vulnerability Assessment(ReVA) program has focused much of its research over the last five years on developing and evaluating integration methods for spatial data. An initial strategic priority was to use existing data from monitoring programs, model results, and other spatial data. Because most of these data were not collected with an intention of integrating into a regional assessment of conditions and vulnerabilities, issues exist that may preclude the use of some methods or require some sort of data preparation. Additionally, to support multi-criteria decision-making, methods need to be able to address a series of assessment questions that provide insights into where environmental risks are a priority. This paper provides an overview of twelve spatial integration methods that can be applied towards regional assessment, along with preliminary results as to how sensitive each method is to data issues that will likely be encountered with the use of existing data.

Overview of Fuel Rod Simulator Usage at ORNL

NASA Astrophysics Data System (ADS)

Ott, Larry J.; McCulloch, Reg

2004-02-01

During the 1970s and early 1980s, the Oak Ridge National Laboratory (ORNL) operated large out-of-reactor experimental facilities to resolve thermal-hydraulic safety issues in nuclear reactors. The fundamental research ranged from material mechanical behavior of fuel cladding during the depressurization phase of a loss-of-coolant accident (LOCA) to basic heat transfer research in gas- or sodium-cooled cores. The largest facility simulated the initial phase (less than 1 min. of transient time) of a LOCA in a commercial pressurized-water reactor. The nonnuclear reactor cores of these facilities were mimicked via advanced, highly instrumented electric fuel rod simulators locally manufactured at ORNL. This paper provides an overview of these experimental facilities with an emphasis on the fuel rod simulators.

The Plight of Chicano Students: An Overview of Schooling Conditions and Outcomes. Chapter 1.

ERIC Educational Resources Information Center

Valencia, Richard R.

This chapter addresses the Chicano schooling experience by presenting an overview of the conditions and outcomes of Chicano schooling problems. School failure among Chicano students refers to their persistently, pervasively, and disproportionately low academic achievement. For example, in 1979 the average number of years Chicanos remained in…

An overview of ecological and evolutionary research on disease in natural systems: an annotated reference list

Treesearch

Helen M. Alexander

2012-01-01

The Fourth International Workshop on the Genetics of Host-Parasite Interactions in Forestry (July 31-August 5, 2011) included a session on “Ecology and Evolutionary Biology of Resistance and Tolerance, Natural Systems.” Within this session, I gave a talk entitled “An overview of ecological and evolutionary research on disease in ‘natural’ systems” that reviewed...

Interventions for sustained healthcare professional behaviour change: a protocol for an overview of reviews.

PubMed

Dombrowski, Stephan U; Campbell, Pauline; Frost, Helen; Pollock, Alex; McLellan, Julie; MacGillivray, Steve; Gavine, Anna; Maxwell, Margaret; O'Carroll, Ronan; Cheyne, Helen; Presseau, Justin; Williams, Brian

2016-10-13

Failure to successfully implement and sustain change over the long term continues to be a major problem in health and social care. Translating evidence into routine clinical practice is notoriously complex, and it is recognised that to implement new evidence-based interventions and sustain them over time, professional behaviour needs to change accordingly. A number of theories and frameworks have been developed to support behaviour change among health and social care professionals, and models of sustainability are emerging, but few have translated into valid and reliable interventions. The long-term success of healthcare professional behavioural change interventions is variable, and the characteristics of successful interventions unclear. Previous reviews have synthesised the evidence for behaviour change, but none have focused on sustainability. In addition, multiple overlapping reviews have reported inconsistent results, which do not aid translation of evidence into practice. Overviews of reviews can provide accessible succinct summaries of evidence and address barriers to evidence-based practice. We aim to compile an overview of reviews, identifying, appraising and synthesising evidence relating to sustained social and healthcare professional behaviour change. We will conduct a systematic review of Cochrane reviews (an Overview). We plan to systematically search the Cochrane Database of Systematic Reviews. We will include all systematic reviews of randomised controlled trials comparing a healthcare professional targeted behaviour change intervention to a standard care or no intervention control group. Two reviewers will independently assess the eligibility of the reviews and the methodological quality of included reviews using the ROBIS tool. The quality of evidence within each comparison in each review will be judged based on the GRADE criteria. Disagreements will be resolved through discussion. Effects of interventions will be systematically tabulated and the

Nitrogen dynamics in flooded soil systems: an overview on concepts and performance of models.

PubMed

Nurulhuda, Khairudin; Gaydon, Donald S; Jing, Qi; Zakaria, Mohamad P; Struik, Paul C; Keesman, Karel J

2018-02-01

Extensive modelling studies on nitrogen (N) dynamics in flooded soil systems have been published. Consequently, many N dynamics models are available for users to select from. With the current research trend, inclined towards multidisciplinary research, and with substantial progress in understanding of N dynamics in flooded soil systems, the objective of this paper is to provide an overview of the modelling concepts and performance of 14 models developed to simulate N dynamics in flooded soil systems. This overview provides breadth of knowledge on the models, and, therefore, is valuable as a first step in the selection of an appropriate model for a specific application. © 2017 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. © 2017 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

An overview on the reactors to study drinking water biofilms.

PubMed

Gomes, I B; Simões, M; Simões, L C

2014-10-01

The development of biofilms in drinking water distribution systems (DWDS) can cause pipe degradation, changes in the water organoleptic properties but the main problem is related to the public health. Biofilms are the main responsible for the microbial presence in drinking water (DW) and can be reservoirs for pathogens. Therefore, the understanding of the mechanisms underlying biofilm formation and behavior is of utmost importance in order to create effective control strategies. As the study of biofilms in real DWDS is difficult, several devices have been developed. These devices allow biofilm formation under controlled conditions of physical (flow velocity, shear stress, temperature, type of pipe material, etc), chemical (type and amount of nutrients, type of disinfectant and residuals, organic and inorganic particles, ions, etc) and biological (composition of microbial community - type of microorganism and characteristics) parameters, ensuring that the operational conditions are similar as possible to the DWDS conditions in order to achieve results that can be applied to the real scenarios. The devices used in DW biofilm studies can be divided essentially in two groups, those usually applied in situ and the bench top laboratorial reactors. The selection of a device should be obviously in accordance with the aim of the study and its advantages and limitations should be evaluated to obtain reproducible results that can be transposed into the reality of the DWDS. The aim of this review is to provide an overview on the main reactors used in DW biofilm studies, describing their characteristics and applications, taking into account their main advantages and limitations. Copyright © 2014 Elsevier Ltd. All rights reserved.

Evaluation of interventions to prevent injuries: an overview

PubMed Central

Dannenberg, A.; Fowler, C.

1998-01-01

Overview of issues involved in evaluating the effectiveness of injury interventions is presented. An intervention should be evaluated to show it prevents injuries in the target population, to identify unintended consequences, to correct problems that limit effectiveness, to justify current and future resources from funding agencies, and to guide its replication elsewhere. Problems in conducting evaluations include obtaining sufficient resources, coping with rare events, establishing reliability and validity of measurement instruments, separating effects of multiple simultaneous events, and adjusting for the time lag between an intervention and its effects. When feasible, changes in injury rates (documented by medical records) should be used. These are more convincing for demonstrating intervention effectiveness than changes in observed or reported behaviors or in knowledge and attitudes (documented by surveys). Quasiexperimental evaluation designs are often useful, such as measuring injury rates before and after an intervention in a time series design, or intervening in one of two comparable communities in a non-equivalent control group design. Evaluations using true experimental designs, in which individuals or groups are randomized to receive or not receive an intervention, are highly desirable but are often difficult due to logistical or ethical considerations. An evaluation component should be integral to the introduction of any new injury intervention. PMID:9666371

An overview on hepatoprotective effects of thymoquinone.

PubMed

Noorbakhsh, Mohammad-Foad; Hayati, Farzad; Samarghandian, Saeed; Shaterzadeh-Yazdi, Hanieh; Farkhondeh, Tahereh

2018-02-20

Liver as an essential organ has an important function in metabolism and waste secretion from the body. Disorders of this organ may caused by several reasons such as high alcoholic consumption, various chemical or microbial agents and various hepatic cancers. Reactive and oxidative stress and oxygen species (ROS) are introduced the main mechanisms of these hepatic injuries. The seeds of Nigella sativa (Family Ranunculaceae) which is known as black seed, is widely used as a medicinal herb for cure or prevention of many of diseases such as liver problems. Thymoquinone (TQ) as a bioactive phytochemical constituent of Nigella sativa has hepatoprotective effects against of injures through different mechanisms including radical scavenging. This review describes protective role and related mechanism of TQ against liver injuries. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Genetic data simulators and their applications: an overview

PubMed Central

Peng, Bo; Chen, Huann-Sheng; Mechanic, Leah E.; Racine, Ben; Clarke, John; Gillanders, Elizabeth; Feuer, Eric J.

2016-01-01

Computer simulations have played an indispensable role in the development and application of statistical models and methods for genetic studies across multiple disciplines. The need to simulate complex evolutionary scenarios and pseudo-datasets for various studies has fueled the development of dozens of computer programs with varying reliability, performance, and application areas. To help researchers compare and choose the most appropriate simulators for their studies, we have created the Genetic Simulation Resources (GSR) website, which allows authors of simulation software to register their applications and describe them with more than 160 defined attributes. This article summarizes the properties of 93 simulators currently registered at GSR and provides an overview of the development and applications of genetic simulators. Unlike other review articles that address technical issues or compare simulators for particular application areas, we focus on software development, maintenance, and features of simulators, often from a historical perspective. Publications that cite these simulators are used to summarize both the applications of genetic simulations and the utilization of simulators. PMID:25504286

An Overview of Chain of Custody Options for LETTERPRESS.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smartt, Heidi A.

2016-11-01

This purpose of this document is to provide an overview of Chain of Custody (CoC) technology options that could be made available for the LETTERPRESS exercise as part of the Quad Working Group. The Quad Working Group comprises five sub-working groups (Management, Protocol, Simulation, Technology, and Training) with members from the U.S., U.K., Norway, and Sweden having the goal of providing a repeatable, realistic arms control exercise (dubbed LETTERPRESS) to be executed in representative facilities and using non-proliferative but representative treaty items. The Technology Working Group is responsible for supporting the technology requirements of the LETTERPRESS exercise and as suchmore » the technologies presented here are possible options to meet those requirements.« less

An Overview of Atmospheric Chemistry and Air Quality Modeling

NASA Technical Reports Server (NTRS)

Johnson, Matthew S.

2017-01-01

This presentation will include my personal research experience and an overview of atmospheric chemistry and air quality modeling to the participants of the NASA Student Airborne Research Program (SARP 2017). The presentation will also provide examples on ways to apply airborne observations for chemical transport (CTM) and air quality (AQ) model evaluation. CTM and AQ models are important tools in understanding tropospheric-stratospheric composition, atmospheric chemistry processes, meteorology, and air quality. This presentation will focus on how NASA scientist currently apply CTM and AQ models to better understand these topics. Finally, the importance of airborne observation in evaluating these topics and how in situ and remote sensing observations can be used to evaluate and improve CTM and AQ model predictions will be highlighted.

An overview of the issues: physiological effects of bed rest and restricted physical activity

NASA Technical Reports Server (NTRS)

Convertino, V. A.; Bloomfield, S. A.; Greenleaf, J. E.

1997-01-01

Reduction of exercise capacity with confinement to bed rest is well recognized. Underlying physiological mechanisms include dramatic reductions in maximal stroke volume, cardiac output, and oxygen uptake. However, bed rest by itself does not appear to contribute to cardiac dysfunction. Increased muscle fatigue is associated with reduced muscle blood flow, red cell volume, capillarization and oxidative enzymes. Loss of muscle mass and bone density may be reflected by reduced muscle strength and higher risk for injury to bones and joints. The resultant deconditioning caused by bed rest can be independent of the primary disease and physically debilitating in patients who attempt to reambulate to normal active living and working. A challenge to clinicians and health care specialists has been the identification of appropriate and effective methods to restore physical capacity of patients during or after restricted physical activity associated with prolonged bed rest. The examination of physiological responses to bed rest deconditioning and exercise training in healthy subjects has provided significant information to develop effective rehabilitation treatments. The successful application of acute exercise to enhance orthostatic stability, daily endurance exercise to maintain aerobic capacity, or specific resistance exercises to maintain musculoskeletal integrity rather than the use of surgical, pharmacological, and other medical treatments for clinical conditions has been enhanced by investigation and understanding of underlying mechanisms that distinguish physical deconditioning from the disease. This symposium presents an overview of cardiovascular and musculoskeletal deconditioning associated with reduced physical work capacity following prolonged bed rest and exercise training regimens that have proven successful in ameliorating or reversing these adverse effects.

Transparent Conducting Oxides—An Up-To-Date Overview

PubMed Central

Stadler, Andreas

2012-01-01

Transparent conducting oxides (TCOs) are electrical conductive materials with comparably low absorption of electromagnetic waves within the visible region of the spectrum. They are usually prepared with thin film technologies and used in opto-electrical apparatus such as solar cells, displays, opto-electrical interfaces and circuitries. Here, based on a modern database-system, aspects of up-to-date material selections and applications for transparent conducting oxides are sketched, and references for detailed information are given. As n-type TCOs are of special importance for thin film solar cell production, indium-tin oxide (ITO) and the reasonably priced aluminum-doped zinc oxide (ZnO:Al), are discussed with view on preparation, characterization and special occurrences. For completion, the recently frequently mentioned typical p-type delafossite TCOs are described as well, providing a variety of references, as a detailed discussion is not reasonable within an overview publication. PMID:28817002

An Overview of New Technologies Driving Innovation in the Airborne Science Community

NASA Technical Reports Server (NTRS)

Fladeland, Matthew M.

2017-01-01

Following a more than a century of scientific aircraft and ballooning there is a sense that a renaissance of sorts is at hand in the aviation industry. The advent of incredibly miniaturized autopilots, inertial navigation systems, GPS antennae, and payloads has sparked a revolution in manned and unmanned aircraft. Improved SATCOM and onboard computing has enabled realtime data processing and improved transfer of data on and off the aircraft, making flight planning and data collection more efficient and effective. Electric propulsion systems are scaling up to larger and larger vehicles as evidenced by the NASA GL-10, which is leading to a new X-plane and is leading to renewed interest in personal air vehicles. There is also significant private and government investments in the development of High Altitude, Long Endurance (HALE) aircraft. This presentation will explore how such developments are likely to improve our ability to observe earth systems processes from aircraft by providing an overview of current NASA Airborne Science capabilities, followed by a brief discussion of new technologies being applied to Airborne Science missions, and then conclude with an overview of new capabilities on the horizon that are likely to be of interest to the Earth Science community.

Music therapy research in Ibero-American countries: an overview focused on assessment and clinical evaluation.

PubMed

Sabbatella, Patricia L

2005-12-01

The aim of this article is to present an overview of some contemporary ideas concerning the status of music therapy research in Ibero-American countries, with a focus on assessment and clinical evaluation of music therapy clinical practice.

Goal-oriented Site Characterization in Hydrogeological Applications: An Overview

NASA Astrophysics Data System (ADS)

Nowak, W.; de Barros, F.; Rubin, Y.

2011-12-01

In this study, we address the importance of goal-oriented site characterization. Given the multiple sources of uncertainty in hydrogeological applications, information needs of modeling, prediction and decision support should be satisfied with efficient and rational field campaigns. In this work, we provide an overview of an optimal sampling design framework based on Bayesian decision theory, statistical parameter inference and Bayesian model averaging. It optimizes the field sampling campaign around decisions on environmental performance metrics (e.g., risk, arrival times, etc.) while accounting for parametric and model uncertainty in the geostatistical characterization, in forcing terms, and measurement error. The appealing aspects of the framework lie on its goal-oriented character and that it is directly linked to the confidence in a specified decision. We illustrate how these concepts could be applied in a human health risk problem where uncertainty from both hydrogeological and health parameters are accounted.

Overview and First Results of an In-situ Stimulation Experiment in Switzerland

NASA Astrophysics Data System (ADS)

Amann, F.; Gischig, V.; Doetsch, J.; Jalali, M.; Valley, B.; Evans, K. F.; Krietsch, H.; Dutler, N.; Villiger, L.

2017-12-01

A decameter-scale in-situ stimulation and circulation (ISC) experiment is currently being conducted at the Grimsel Test Site in Switzerland with the objective of improving our understanding of key seismo-hydro-mechanical coupled processes associated with high pressure fluid injections in a moderately fractured crystalline rock mass. The ISC experiment activities aim to support the development of EGS technology by 1) advancing the understanding of fundamental processes that occur within the rock mass in response to relatively large-volume fluid injections at high pressures, 2) improving the ability to estimate and model induced seismic hazard and risks, 3) assessing the potential of different injection protocols to keep seismic event magnitudes below an acceptable threshold, 4) developing novel monitoring and imaging techniques for pressure, temperature, stress, strain and displacement as well as geophysical methods such as ground penetration radar, passive and active seismic and 5) generating a high-quality benchmark datasets that facilitates the development and validation of numerical modelling tools. The ISC experiment includes six fault slip and five hydraulic fracturing experiments at an intermediate scale (i.e. 20*20*20m) at 480m depth, which allows high resolution monitoring of the evolution of pore pressure in the stimulated fault zone and the surrounding rock matrix, fault dislocations including shear and dilation, and micro-seismicity in an exceptionally well characterized structural setting. In February 2017 we performed the fault-slip experiments on interconnected faults. Subsequently an intense phase of post-stimulation hydraulic characterization was performed. In Mai 2017 we performed hydraulic fracturing tests within test intervals that were free of natural fractures. In this contribution we give an overview and show first results of the above mentioned stimulation tests.

Radial magnetic bearings: An overview

NASA Astrophysics Data System (ADS)

Zhang, Weiyu; Zhu, Huangqiu

Radial magnetic bearings (RMBs) are one of the most commonly used magnetic bearings. They are used widely in the field of ultra-high speed and ultra-precise numerical control machine tools, bearingless motors, high speed flywheels, artificial heart pumps, and molecular pumps, and they are being strengthened and extended in various important areas. In this paper, a comprehensive overview is given of different bearing topologies of RMBs with different stator poles that differ in their construction, the driving mode of electromagnets, power consumption, cost, magnetic circuits, and symmetry. RMBs with different poles and couplings between the two bearing axes in the radial direction responsible for cross-coupling generation are compared. In addition, different shaped rotors are compared, as the performances of magnetic bearing-rotor systems are of great concern to rotor constructions. Furthermore, the parameter design methods, the mathematical models and control strategies of the RMBs are described in detail. From the comparison of topologies, models and control methods for RMBs, the advantages, disadvantages and utilizable perspectives are also analyzed. Moreover, several possible development trends of the RMBs are discussed.

Antifungal Resistance, Metabolic Routes as Drug Targets, and New Antifungal Agents: An Overview about Endemic Dimorphic Fungi

PubMed Central

Parente-Rocha, Juliana Alves; Bailão, Alexandre Melo; Amaral, André Correa; Paccez, Juliano Domiraci; Borges, Clayton Luiz

2017-01-01

Diseases caused by fungi can occur in healthy people, but immunocompromised patients are the major risk group for invasive fungal infections. Cases of fungal resistance and the difficulty of treatment make fungal infections a public health problem. This review explores mechanisms used by fungi to promote fungal resistance, such as the mutation or overexpression of drug targets, efflux and degradation systems, and pleiotropic drug responses. Alternative novel drug targets have been investigated; these include metabolic routes used by fungi during infection, such as trehalose and amino acid metabolism and mitochondrial proteins. An overview of new antifungal agents, including nanostructured antifungals, as well as of repositioning approaches is discussed. Studies focusing on the development of vaccines against antifungal diseases have increased in recent years, as these strategies can be applied in combination with antifungal therapy to prevent posttreatment sequelae. Studies focused on the development of a pan-fungal vaccine and antifungal drugs can improve the treatment of immunocompromised patients and reduce treatment costs. PMID:28694566

Buoyancy-generating agents for stomach-specific drug delivery: an overview with special emphasis on floating behavior.

PubMed

Ishak, Rania A H

2015-01-01

Gastric retentive drug delivery provides a promising technology exhibiting an extended gastric residence and a drug release independent of patient related variables. It is usually useful in improving local gastric treatment as well as overcoming drug-related problems .i.e. drugs having narrow absorption window, short half-life or low intestinal solubility. Buoyancy is considered one of the most promising approaches for gastro-retention of dosage forms. Floating drug delivery systems have a bulk density lower than gastric fluids and thus remain buoyant in the stomach causing an increase in gastric residence time. The buoyancy of these systems is attained by the aid of substances responsible to generate the low density. Various agents with different mechanisms were adopted either gas-generating agents, air entrapping swellable polymers, inherent low density substances, porous excipients, hollow/porous particles inducing preparation techniques or sublimating agents. Therefore, this review gives an exclusive descriptive classification of the different categories of these buoyancy-generating agents while representing the related research works. An overview is also conducted to describe relevant techniques assessing the floating behavior of such dosage forms either in vitro or in vivo. Finally, a collection representing FDA-approved floating pharmaceutical products is adopted with emphasis on the buoyancy-generating agent type used in each product.

Epigenetic mechanisms in schizophrenia

PubMed Central

Roth, Tania L.; Lubin, Farah D.; Sodhi, Monsheel; Kleinman, Joel E.

2009-01-01

Summary Epidemiological research suggests that both an individual’s genes and the environment underlie the pathophysiology of schizophrenia. Molecular mechanisms mediating the interplay between genes and the environment are likely to have a significant role in the onset of the disorder. Recent work indicates that epigenetic mechanisms, or the chemical markings of the DNA and the surrounding histone proteins, remain labile through the lifespan and can be altered by environmental factors. Thus, epigenetic mechanisms are an attractive molecular hypothesis for environmental contributions to schizophrenia. In this review, we first present an overview of schizophrenia and discuss the role of nature versus nurture in its pathology, where ‘nature’ is considered to be inherited or genetic vulnerability to schizophrenia, and ‘nurture’ is proposed to exert its effects through epigenetic mechanisms. Second, we define DNA methylation and discuss the evidence for its role in schizophrenia. Third, we define posttranslational histone modifications and discuss their place in schizophrenia. This research is likely to lead to the development of epigenetic therapy, which holds the promise of alleviating cognitive deficits associated with schizophrenia. PMID:19559755

Malignant sex and aggression: an overview of serial sexual homicide.

PubMed

Myers, W C; Reccoppa, L; Burton, K; McElroy, R

1993-01-01

Serial murderers have attracted considerable attention in the popular press and criminal justice field, but scientific literature about these individuals is limited. This article provides an overview, from a psychiatric perspective, of serial sexual homicide, one type of serial killing. Characteristics of this type of murder and of these offenders are discussed. Defining qualities and diagnoses applicable to serial sexual killers are reviewed. Various etiologic theories are discussed, with emphasis on the role of fantasy and psychodynamic explanations. Governmental agencies involved in combating this type of crime, along with the role of mental health professionals in criminal profiling, are presented. Finally, the authors explore the reaction of society to this phenomenon.

An overview of depression in the elderly: a US perspective.

PubMed Central

Baker, F. M.

1996-01-01

This article is organized in seven sections. The first section presents a review of the existing epidemiologic data on the prevalence of depressive illness in different, elderly US populations (community residents versus the medically ill). Section two describes the US elderly population. Section three describes three presentations of depression in the elderly. Section four addresses the outcome of depressive disorder untreated or partially treated. In section five the data on suicide in the elderly is reviewed. An overview of specific considerations for the psychopharmacologic and psychotherapeutic treatment of depression is presented in section six. Section seven provides a summary of the major points of the article. PMID:8839033

Alan Stone and the ethics of forensic psychiatry: an overview.

PubMed

Miller, Glenn H

2008-01-01

In 1982, Alan Stone presented a keynote speech at the Annual Meeting of the American Academy of Psychiatry and the Law (AAPL) on the ethics of forensic psychiatry. That speech was sharply critical of the prevailing ethics standards and led forensic psychiatrists to study his ideas carefully. A quarter-century later, he returned to the AAPL's Annual Meeting to present his current thinking. This overview outlines the development of Stone's thought over 25 years and the dialectic among Stone and three critics: Paul Appelbaum, Ezra Griffith, and Stephen Morse. Stone is now more optimistic about the possibility of developing an ethic for forensic psychiatry.

An Overview of the James Webb Space Telescope (JWST) Project

NASA Technical Reports Server (NTRS)

Sabelhaus, Phillip A.

2004-01-01

The JWST project at the GSFC is responsible for the development, launch, operations and science data processing for the James Webb Space Telescope. The JWST project is currently in phase B with its launch scheduled for August 2011. The project is a partnership between NASA, ESA and CSA. The U.S. JWST team is now fully in place with the recent selection of Northrop Grumman Space Technology (NGST) as the prime contractor for the telescope and the Space Telescope Science Institute (STScI) as the mission operations and science data processing lead. This paper will provide an overview of the current JWST architecture and mission status including technology developments and risks.

An Overview of the James Webb Space Telescope (JWST) Project

NASA Technical Reports Server (NTRS)

Sabelhaus, Phillip A.; Campbell, Doug; Clampin, Mark; Decker, John; Greenhouse, Matt; Johns, Alan; Menzel, Mike; Smith, Robert; Sullivan, Pam

2005-01-01

The JWST project at the GSFC is responsible for the development, launch, operations and science data processing for the James Webb Space Telescope. The JWST project is currently in phase B with its launch scheduled for August 2011. The project is a partnership between NASA, ESA and CSA. The U.S. JWST team is now fully in place with the selection of Northrop Grumman Space Technology (NGST) as the prime contractor for the telescope and the Space Telescope Science Institute (STScI) as the mission operations and science data processing lead. This paper will provide an overview of the current JWST architecture and mission status including technology developments and risks.

An Overview of Low-Emission Combustion Research at NASA Glenn

NASA Technical Reports Server (NTRS)

Reddy, Dhanireddy R.; Lee, Chi-Ming

2016-01-01

An overview of research efforts at NASA Glenn Research Center (GRC) in low-emission combustion technology that have made a significant impact on the nitrogen oxides (NOx) emission reduction in aircraft propulsion is presented. The technology advancements and their impact on aircraft emissions are discussed in the context of NASA's Aeronautics Research Mission Directorate (ARMD) high-level goals in fuel burn, noise and emission reductions. The highlights of the research presented here show how the past and current efforts laid the foundation for the engines that are flying today as well as how the continued technology advancements will significantly influence the next generation of aviation propulsion system designs.

An overview of in-flight plume diagnostics for rocket engines

NASA Technical Reports Server (NTRS)

Madzsar, G. C.; Bickford, R. L.; Duncan, D. B.

1992-01-01

An overview and progress report of the work performed or sponsored by LeRC toward the development of in-flight plume spectroscopy technology for health and performance monitoring of liquid propellant rocket engines are presented. The primary objective of this effort is to develop technology that can be utilized on any flight engine. This technology will be validated by a hardware demonstration of a system capable of being retrofitted onto the Space Shuttle Main Engines for spectroscopic measurements during flight. The philosophy on system definition and status on the development of instrumentation, optics, and signal processing with respect to implementation on a flight engine are discussed.

Lessons Learned and Lessons To Be Learned: An Overview of Innovative Network Learning Environments.

ERIC Educational Resources Information Center

Jacobson, Michael J.; Jacobson, Phoebe Chen

This paper provides an overview of five innovative projects involving network learning technologies in the United States: (1) the MicroObservatory Internet Telescope is a collection of small, high-quality, and low-maintenance telescopes operated by the Harvard-Smithsonian Center for Astrophysics (Massachusetts), which may be used remotely via the…

An Overview of Markov Chain Methods for the Study of Stage-Sequential Developmental Processes

ERIC Educational Resources Information Center

Kapland, David

2008-01-01

This article presents an overview of quantitative methodologies for the study of stage-sequential development based on extensions of Markov chain modeling. Four methods are presented that exemplify the flexibility of this approach: the manifest Markov model, the latent Markov model, latent transition analysis, and the mixture latent Markov model.…

Technology advancements for the U.S. manned Space Station - An overview

NASA Technical Reports Server (NTRS)

Simon, William E.

1987-01-01

The structure and methodology of the Johnson Space Center (JSC) advanced development program is described. An overview of the program is given, and the technology transfer process to other disciplines is described. The test bed and flight experiment programs are described, as is the technology assessment which was performed at the end of the Phase B program. The technology program within each discipline is summarized, and the coordination and integration of the JSC program with the activities of other NASA centers and with work package contractors are discussed.

Student Count Mechanisms for Funding Purposes. Education Policy Brief, Volume 10, Number 2, Spring 2012

ERIC Educational Resources Information Center

Lara, Lindsi M.; Spradlin, Terry E.; Wodicka, Christopher Y.

2012-01-01

This Education Policy Brief provides an overview of the student count mechanisms that are currently employed by states. It then reviews Indiana's outgoing count mechanism, the Single Count Date, and compares it with the newly enacted Multiple Count Dates mechanism. To conclude the discussion, the brief examines how other states use the Multiple…

Competency-based medical education: An overview and application in pharmacology

PubMed Central

Shah, Nilima; Desai, Chetna; Jorwekar, Gokul; Badyal, Dinesh; Singh, Tejinder

2016-01-01

Competency-based medical education (CBME) is gaining momentum across the globe. The Medical Council of India has described the basic competencies required of an Indian Medical Graduate and designed a competency-based module on attitudes and communication. Widespread adoption of a competency-based approach would mean a paradigm shift in the current approach to medical education. CBME, hence, needs to be reviewed for its usefulness and limitations in the Indian context. This article describes the rationale of CBME and provides an overview of its components, i.e., competency, entrustable professional activity, and milestones. It elaborates how CBME could be implemented in an institute, in the context of basic sciences in general and pharmacology in particular. The promises and perils of CBME that need to be kept in mind to maximize its gains are described. PMID:28031599

An Overview of the History of Library Science Teaching Materials.

ERIC Educational Resources Information Center

Metzger, Philip A.

1986-01-01

This introduction to, and overview of, history of library science instructional materials covers the Williamson Report, teaching materials from early Columbia days onward, American Library Association book publishing activity, media in curricula and library school publication of syllabi, commercial publishing of textbooks, and periodicals in…

NASA. Lewis Research Center materials research and technology: An overview

NASA Technical Reports Server (NTRS)

Grisaffe, Salvatore J.

1990-01-01

The Materials Division at the Lewis Research Center has a long record of contributions to both materials and process technology as well as to the understanding of key high-temperature phenomena. This paper overviews the division staff, facilities, past history, recent progress, and future interests.