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Sample records for medicine london uk

  1. The 2015 Pregnancy Summit, London, UK.

    PubMed

    Johansson, Cherynne

    2016-01-01

    Pregnancy Summit, Cineworld, The O2, London, UK, 29 September to 1 October 2015 The 2015 Pregnancy Summit was held over 3 days from 29 September to 1 October at Cineworld, The O2, London, UK. The event brings together a multidisciplinary faculty of international researchers and clinicians to discuss both scientific and clinical aspects of pregnancy-related issues in an informal setting. The goal of the meeting was to provide delegates with an update of recent advances in management of pregnancy-related conditions, to present research data and to discuss the current attitudes and practices in relevant topics. An extensive range of topics were discussed, from preeclampsia and treatment of hypertension, to the psychological impact of termination of pregnancy and feticide. This report will summarize a selection of the lectures presented.

  2. Pharmacovigilance Discussion Forum--The European Generic Medicines Association's 8th Annual Meeting (January 21, 2015--London, UK).

    PubMed

    Lam, S

    2015-01-01

    The practice and science of pharmacovigilance first emerged following the disaster caused by thalidomide in 1961, which led to the initiation of systemic international efforts to address drug safety issues spearheaded by the WHO. Systems were developed in member states of the WHO to analyze cases of adverse drug reactions (ADRs) and collate these data into a central database to aid national drug regulatory authorities in improving safety profiles of medicines. Pharmacovigilance is a key public health function for monitoring all medicinal products to assess their quality, efficacy and safety before and following authorization. These medicines are continually assessed to detect any aspect that could compromise their safety, and ensure that the necessary measures are taken. In July 2012, new legislation for pharmacovigilance in the E.U. came into effect as a result of the changes set out in the Directive 2010/84/EU and the European Commission (EC) implementing Regulation (EU) No 520/2012 to reduce the increasing number of ADRs. The latest developments in pharmacovigilance in Europe, including news on E.U. pharmacovigilance legislation, were discussed at the 8th European Generic Medicines Association (EGA) Pharmacovigilance Discussion Forum. The meeting facilitated constructive dialogue between regulators and industry on a range of topics including how to simplify pharmacovigilance activities and improve the processes of risk management plans, periodic safety update reports, signal detection, joint studies and inspections.

  3. Acheiving speech intelligibility at Paddington Station, London, UK

    NASA Astrophysics Data System (ADS)

    Goddard, Helen M.

    2002-11-01

    Paddington Station in London, UK is a large rail terminus for long distance electric and diesel powered trains. This magnificent train shed has four arched spans and is one of the remaining structural testaments to the architect Brunel. Given the current British and European legislative requirements for intelligible speech in public buildings AMS Acoustics were engaged to design an electroacoustic solution. In this paper we will outline how the significant problems of lively natural acoustics, the high operational noise levels and the strict aesthetic constraints were addressed. The resultant design is radical, using the most recent dsp controlled line array loudspeakers. In the paper we detail the acoustic modeling undertaken to predict both even direct sound pressure level coverage and STI. Further it presents the speech intelligibility measured upon handover of the new system. The design has proved to be successful and given the nature of the space, outstanding speech intelligibility is achieved.

  4. Carbon dioxide and methane emission dynamics in central London (UK)

    NASA Astrophysics Data System (ADS)

    Helfter, Carole; Nemitz, Eiko; Barlow, Janet F.; Wood, Curtis R.

    2013-04-01

    London, with a population of 8.2 million, is the largest city in Europe. It is heavily built-up (typically 8% vegetation cover within the central boroughs) and boasts some of the busiest arteries in Europe despite efforts to reduce traffic in the city centre with the introduction of a congestion charging scheme in 2007. We report on two substantial pollution monitoring efforts in the heart of London between October 2006 and present. Fluxes of carbon dioxide (CO2) and water (H2O) were measured continuously by eddy-covariance in central London from October 2006 until May 2008 from a 190 m telecommunication tower (BT tower; 51° 31' 17.4'' N 0° 8' 20.04'' W). The eddy-covariance system consisted of a Gill R3-50 ultrasonic anemometer operated at 20 Hz and a LI-COR 6262 infrared gas analyser. Air was sampled 0.3 m below the sensor head of the ultrasonic anemometer - which was itself mounted on a 3 m mast to the top of a 15 m lattice tower situated on the roof of the tower (instrument head at 190 m above street level) - and pulled down 45 m of 12.7 mm OD Teflon tubing. In addition, meteorological variables (temperature, relative humidity, pressure, precipitation, wind speed and direction) were also measured with a multi-sensor (Weather Transmitter WXT510, Vaisala). Eddy-covariance measurements at the BT tower location were reinstated in July 2011 and include methane (CH4), CO2 and H2O concentrations measured by a Picarro fast methane analyser (G2301-f). CO2 emissions were found to be mainly controlled by fossil fuel combustion (e.g. traffic, commercial and domestic heating). Diurnal averages of CO2 fluxes were found to be highly correlated to traffic. However changes in heating-related natural gas consumption and, to a lesser extent, photosynthetic activity in two large city centre green spaces (Hyde Park and Regent's Park) explained the seasonal variability. Annual estimates of net exchange of CO2 obtained by eddy-covariance agreed well with up-scaled data from the UK

  5. Summary of inaugural meeting of the Skin Care in Organ Recipients Group, UK, held at the Royal Society of Medicine, 7 October 2004.

    PubMed

    Eedy, D J

    2005-07-01

    This summarizes a meeting held in London at the Royal Society of Medicine, which was brought together by Prof. Fenella Wojnarowska, Professor of Dermatology at Churchill Hospital, Oxford and cofounder of Skin Care in Organ Recipients, UK (SCOR.UK).

  6. The licensing of medicines in the UK.

    PubMed

    2009-04-01

    Before a medicinal product* can be marketed in the UK, a marketing authorisation (formerly called a 'product licence') is needed. Such an authorisation can be granted in the European Union (EU), via the European Medicines Agency (EMEA), European Commission (EC) and member state's competent authorities or, specifically in the UK, via the Medicines and Healthcare product Regulatory Agency (MHRA) on behalf of the UK licensing authority.2(-)4 Also, a change to the authorisation is needed if the licensing status of a medicine is changed; for example, from a prescription-only medicine (POM) to a pharmacy medicine (P). Here we look at the procedures involved in the licensing of medicines (including herbal and homoeopathic products) for use in the UK.

  7. Betel nut use among first and second generation Bangladeshi women in London, UK.

    PubMed

    Núñez-de la Mora, Alejandra; Jesmin, Fahmida; Bentley, Gillian R

    2007-10-01

    This study evaluated the effects of socio-economic variables and migration history on the prevalence of betel nut and smokeless tobacco use in both UK- and Bangladeshi born migrant women resident in London. No significant difference in betel nut use prevalence was found among women of different generations. However, in all groups betel nut users were significantly older and less educated than non-users. Among first generation women there was no effect of either length of time living in the UK or age at migration on use of betel nut, even after controlling for current age. No significant differences in prevalence use due to language spoken, occupation, marital status or borough of residence in London were found. We conclude that, although there are some indications of a change in behavior among younger individuals, betel nut chewing is a practice very much present among Bangladeshi women born and brought up in a bicultural context.

  8. Pseudoislets as primary islet replacements for research: report on a symposium at King's College London, London UK.

    PubMed

    Persaud, Shanta J; Arden, Catherine; Bergsten, Peter; Bone, Adrian J; Brown, James; Dunmore, Simon; Harrison, Moira; Hauge-Evans, Astrid; Kelly, Catriona; King, Aileen; Maffucci, Tania; Marriott, Claire E; McClenaghan, Neville; Morgan, Noel G; Reers, Christina; Russell, Mark A; Turner, Mark D; Willoughby, Emma; Younis, Mustafa Y G; Zhi, Z L; Jones, Peter M

    2010-01-01

    Laboratory-based research aimed at understanding processes regulating insulin secretion and mechanisms underlying β-cell dysfunction and loss in diabetes often makes use of rodents, as these processes are in many respects similar between rats/mice and humans. Indeed, a rough calculation suggests that islets have been isolated from as many as 150,000 rodents to generate the data contained within papers published in 2009 and the first four months of 2010. Rodent use for islet isolation has been mitigated, to a certain extent, by the availability of a variety of insulin-secreting cell lines that are used by researchers world-wide. However, when maintained as monolayers the cell lines do not replicate the robust, sustained secretory responses of primary islets which limits their usefulness as islet surrogates. On the other hand, there have been several reports that configuration of MIN6 β-cells, derived from a mouse insulinoma, as three-dimensional cell clusters termed ‘pseudoislets’ largely recapitulates the function of primary islet β-cells. The Diabetes Research Group at King’s College London has been using the MIN6 pseudoislet model for over a decade and they hosted a symposium on “Pseudoislets as primary islet replacements for research”, which was funded by the UK National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), in London on 15th and 16th April 2010. This small, focused meeting was conceived as an opportunity to consolidate information on experiences of working with pseudoislets between different UK labs, and to introduce the theory and practice of pseudoislet culture to laboratories working with islets and/or β-cell lines but who do not currently use pseudoislets. This short review summarizes the background to the development of the cell line-derived pseudoislet model, the key messages arising from the symposium and emerging themes for future pseudoislet research.

  9. Modelling lead bioaccessibility in urban topsoils based on data from Glasgow, London, Northampton and Swansea, UK.

    PubMed

    Appleton, J D; Cave, M R; Wragg, J

    2012-12-01

    Predictive linear regression (LR) modelling between bioaccessible Pb and a range of total elemental compositions and soil properties was executed for the Glasgow, London, Northampton and Swansea urban areas in order to assess the potential for developing a national urban bioaccessible Pb dataset for the UK. LR indicates that total Pb is the only highly significant independent variable for estimating the bioaccessibility of Pb. Bootstrap resampling shows that the relationship between total Pb and bioaccessible Pb is broadly the same in the four urban areas. The median bioaccessible fraction ranges from 38% in Northampton to 68% in London and Swansea. Results of this study can be used as part of a lines of evidence approach to localised risk assessment but should not be used to replace bioaccessibility testing at individual sites where local conditions may vary considerably from the broad overview presented in this study.

  10. The Controlling Cancer Summit, 17-19 May 2016, London, UK.

    PubMed

    Babina, Irina S

    2016-10-01

    The Controlling Cancer Summit, London, UK, 17-19 May 2016 The Controlling Cancer Summit is an intimate informal meeting that annually gathers international academic and clinical researchers to network and debate the current advancements and challenges of oncology research. This year, it focused not only on diagnostic/prognostic biomarkers and genetic influences in cancer but also novel and sometimes unconventional therapeutic interventions. This report will summarize the meeting highlights that contribute to our comprehension of cancer biology and new innovative ways to target this disease.

  11. Medical nanotechnology in the UK: a perspective from the London Centre for Nanotechnology.

    PubMed

    Horton, Michael A; Khan, Abid

    2006-03-01

    Nanotechnology research is booming worldwide, and the general belief is that medical and biological applications will form the greatest sector of expansion over the next decade, driven by an attempt to bring radical solutions to areas of unmet medical need. What is true in the United States is also being fulfilled in Europe. This, though, is generally at a significantly lower investment level, even if for "large" capital infrastructure and interdisciplinary centers. Against this, the United Kingdom and its European partners are following the maxim "small is beautiful" and are attempting to identify and develop academic research and commercial businesses in areas that traditional nanotechnology developments involving engineering or physics find challenging. Thus in London-University College London (UCL) in a major joint project with Imperial College and linked to other UK and European centers of excellence-we are building upon our internationally competitive medical research (the two universities together form one of the largest centers of biomedical research outside the United States) to focus on and develop medical nanotechnology as a major sector of our research activity. A novel approach to commercialization has been the establishment with government and private equity funds of a "BioNanotechnology Centre" that will act as a portal for UK industry to access specialist skills to solve issues relating to developing nanotechnology-based medical applications, for example, for environmental screening, diagnostics, and therapy. This article reviews our academic and business strategy with examples from our current biomedical research portfolio.

  12. Bullying, "Cussing" and "Mucking About": Complexities in Tackling Homophobia in Three Secondary Schools in South London, UK

    ERIC Educational Resources Information Center

    Warwick, Ian; Aggleton, Peter

    2014-01-01

    In countries such as the UK, schools have a responsibility to prevent all forms of bullying, including those related to sexual orientation. However, relatively little is known about how schools go about this work successfully. This study aimed to identify how three secondary schools in south London, England, were addressing homophobia. Three…

  13. Measurement of NO(x) fluxes from a tall tower in Central London, UK and comparison with emissions inventories.

    PubMed

    Lee, James D; Helfter, Carole; Purvis, Ruth M; Beevers, Sean D; Carslaw, David C; Lewis, Alastair C; Møller, Sarah J; Tremper, Anja; Vaughan, Adam; Nemitz, Eiko G

    2015-01-20

    Direct measurements of NOx concentration and flux were made from a tall tower in central London, UK as part of the Clean Air for London (ClearfLo) project. Fast time resolution (10 Hz) NO and NO2 concentrations were measured and combined with fast vertical wind measurements to provide top-down flux estimates using the eddy covariance technique. Measured NOx fluxes were usually positive and ranged from close to zero at night to 2000-8000 ng m(-2) s(-1) during the day. Peak fluxes were usually observed in the morning, coincident with the maximum traffic flow. Measurements of the NOx flux have been scaled and compared to the UK National Atmospheric Emissions Inventory (NAEI) estimate of NOx emission for the measurement footprint. The measurements are on average 80% higher than the NAEI emission inventory for all of London. Observations made in westerly airflow (from parts of London where traffic is a smaller fraction of the NOx source) showed a better agreement on average with the inventory. The observations suggest that the emissions inventory is poorest at estimating NOx when traffic is the dominant source, in this case from an easterly direction from the BT Tower. Agreement between the measurements and the London Atmospheric Emissions Inventory (LAEI) are better, due to the more explicit treatment of traffic flow by this more detailed inventory. The flux observations support previous tailpipe observations of higher NOx emitted from the London vehicle diesel fleet than is represented in the NAEI or predicted for several EURO emission control technologies. Higher-than-anticipated vehicle NOx is likely responsible for the significant discrepancies that exist in London between observed NOx and long-term NOx projections.

  14. Monitoring CO2 and CH4 concentrations along an urban-rural transect in London, UK

    NASA Astrophysics Data System (ADS)

    Boon, Alex; Broquet, Gregoire; Clifford, Debbie; Chevallier, Frederic; Butterfield, David

    2013-04-01

    Cities are important sources of carbon dioxide (CO2) and methane (CH4). Anthropogenic CO2 is released in the combustion of fossil fuels for heating, electricity and transport. The major sources of CH4 in city environments are natural gas leakage, landfill sites and transport emissions. Monitoring of urban greenhouse gas concentrations is crucial for cities aiming to reduce emissions through measures such as changes to the transport infrastructure and green planning. We present measurements of CO2 and CH4 concentrations using Cavity Ring-Down Spectroscopy (CRDS) at four sites located in and around London, UK. Two sites were located in the inner city, one in the suburban fringe and the fourth in a rural location close to the city. This study was funded by Astrium Services Ltd as part of a pilot scheme to monitor city-scale GHG emissions and presented a unique opportunity to study changes in greenhouse gas concentrations across an urban to rural 'transect'. The CHIMERE chemistry-transport model is used to estimate CO2 and CH4 concentrations throughout the four month measurement period during the summer of 2012. Comparisons are made between the measured and modelled CO2 and CH4 concentrations and the representativity of the study sites for future urban greenhouse gas monitoring is considered. This study also examines the ability of a variety of measurement and modelling techniques to partition anthropogenic and biogenic CO2 sources.

  15. Fine particle (PM2.5) personal exposure levels in transport microenvironments, London, UK.

    PubMed

    Adams, H S; Nieuwenhuijsen, M J; Colvile, R N; McMullen, M A; Khandelwal, P

    2001-11-12

    In order to investigate a specific area of short-term, non-occupational, human exposure to fine particulate air pollution, measurements of personal exposure to PM2.5 in transport microenvironments were taken in two separate field studies in central London, UK. A high flow gravimetric personal sampling system was used; operating at 16 l min(-1); the sampler thus allowed for sufficient sample mass collection for accurate gravimetric analysis of short-term travel exposure levels over typical single commute times. In total, samples were taken on 465 journeys and 61 volunteers participated. In a multi-transport mode study, carried out over 3-week periods in the winter and in the summer, exposure levels were assessed along three fixed routes at peak and off-peak times of the day. Geometric means of personal exposure levels were 34.5 microg m(-3) (G.S.D.= 1.7, n(s) = 40), 39.0 microg m(-3) (G.S.D. = 1.8, n(s) = 36), 37.7 microg m(-3) (G.S.D. = 1.5, n(s) = 42), and 247.2 microg m(-3) (G.S.D. = 1.3, n(s) = 44) for bicycle, bus, car and Tube (underground rail system) modes, respectively, in the July 1999 (summer) measurement campaign. Corresponding levels in the February 2000 (winter) measurement campaign were 23.5 microg m(-3) (G.S.D. = 1.8, n(s) = 56), 38.9 microg m(-3) (G.S.D. = 2.1, n(s) = 32), 33.7 microg m(-3) (G.S.D. = 2.4, n(s) = 12), and 157.3 microg m(-3) (G.S.D. = 3.3, n(s) = 12), respectively. In a second study, exposure levels were measured for a group of 24 commuters travelling by bicycle, during August 1999, in order to assess how representative the fixed route studies were to a larger commuter population. The geometric mean exposure level was 34.2 microg m(-3) (G.S.D. = 1.9, n(s) = 105). In the fixed-route study, the cyclists had the lowest exposure levels, bus and car were slightly higher, while mean exposure levels on the London Underground rail system were 3-8 times higher than the surface transport modes. There was significant between-route variation

  16. Cervical screening among migrant women: a qualitative study of Polish, Slovak and Romanian women in London, UK

    PubMed Central

    Jackowska, Marta; von Wagner, Christian; Wardle, Jane; Juszczyk, Dorota; Luszczynska, Aleksandra; Waller, Jo

    2012-01-01

    Objective To explore awareness of and participation in cervical screening services in women from Poland, Slovakia and Romania living in London, UK. Methods Three qualitative studies were carried out in London in 2008–2009: an interview study of professionals working with Central and Eastern European migrants (n=11); a focus group study including three Polish, one Slovak and one Romanian focus group; and an interview study of Polish (n=11), Slovak (n=7) and Romanian (n=2) women. Results Awareness of the cervical screening programme was good, but understanding of the purpose of screening was sometimes limited. Some women were fully engaged with the UK screening programme; others used screening both in the UK and their countries of origin; and a third group only had screening in their home countries. Women welcomed the fact that screening is free and that reminders are sent, but some were concerned about the screening interval and the age of the first invitation. Conclusions Migrant women from Poland, Slovakia and Romania living in London vary in their level of participation in the National Health Service Cervical Screening Programme. More needs to be done to address concerns regarding screening services, and to ensure that language is not a barrier to participation. PMID:22219504

  17. Environmental and genetic determinants of vitamin D status among older adults in London, UK.

    PubMed

    Jolliffe, David A; Hanifa, Yasmeen; Witt, Karolina D; Venton, Timothy R; Rowe, Marion; Timms, Peter M; Hyppönen, Elina; Walton, Robert T; Griffiths, Christopher J; Martineau, Adrian R

    2016-11-01

    Despite the high prevalence of vitamin D deficiency among older adults in the UK, studies investigating the determinants of vitamin D status in this group are lacking. We conducted a cross-sectional study in 222 older adults living in sheltered accommodation in London, UK, who were screened for participation in a clinical trial of vitamin D supplementation for the prevention of acute respiratory infection. Details of potential demographic and lifestyle determinants of vitamin D status were collected by questionnaire and blood samples were taken for analysis of serum 25-hydroxyvitamin D (25[OH]D) concentration and DNA extraction. Fifteen single nucleotide polymorphisms (SNP) in 6 genes (DBP, DHCR7, CYP2R1, CYP27B1, CYP24A1, VDR) previously reported to associate with circulating 25(OH)D concentration were typed using Taqman allelic discrimination assays. Linear regression was used to identify environmental and genetic factors independently associated with serum 25(OH)D concentration. Mean serum 25(OH)D concentration was 42.7nmol/L (SD 22.0); 144/222 (64.9%) participants had serum 25(OH)D concentrations <50nmol/L. The following factors were independently associated with lower serum 25(OH)D concentration: non-white ethnicity (-8.6nmol/L, 95% CI -14.9 to -2.3, P=0.008); lack of vitamin D supplement consumption (-17.1nmol/L, 95% CI -23.3 to -10.9, P<0.001) vs. taking a daily supplement; sampling in Q1/January-March (-12.2nmol/L, 95% CI -21.5 to -2.9, P=0.01), and sampling in Q4/October-December (-10.3nmol/L, 95% CI -20.2 to -0.4, P=0.04) vs. sampling in Q3/July-September. None of the 15 SNP investigated independently associated with serum 25(OH)D concentration after correcting for multiple comparisons. In conclusion, vitamin D deficiency was highly prevalent among the older adults in this study; non-White ethnicity, lack of vitamin D supplement consumption and sampling in winter and spring independently associated with lower vitamin D status.

  18. Sources of greenhouse gases and carbon monoxide in central London (UK)

    NASA Astrophysics Data System (ADS)

    Helfter, Carole; Tremper, Anja; Zazzeri, Giulia; Barlow, Janet F.; Nemitz, Eiko

    2015-04-01

    Biosphere-atmosphere exchange of carbon dioxide (CO2) has been on the scientific agenda for several decades and new technology now also allows for high-precision, continuous monitoring of fluxes of methane (CH4) and nitrous oxide (N2O). Compared to the natural environment, flux measurements in the urban environment, which is home to over 50% of the population globally, are still rare despite high densities of anthropogenic sources of pollutants. We report on over three years of measurements atop a 192 m tower in central London (UK), Europe's largest city, which started in October 2011. Fluxes of methane, carbon monoxide (CO) and carbon dioxide are measured by eddy-covariance (EC) at the British Telecom tower (51° 31' 17.4' N 0° 8' 20.04' W). In addition to the long-term measurements, EC fluxes of nitrous oxide (N2O) were measured in February 2014. All four trace gases exhibit diurnal trends consistent with anthropogenic activities with minimum emissions at night and early afternoon maxima. Segregating emissions by wind direction reveals heterogeneous source distributions with temporal patterns and source strengths that differ between compounds. The lowest emissions for CO, CO2 and CH4 were recorded for NW winds. The highest emissions of methane were in the SE sector, in the NE for CO2 and in the W for CO. Fluxes of all 3 gases exhibited marked seasonal trends characterised by a decrease in emissions in summer (63% reduction for CO, 36% for CO2 and 22% for CH4). Monthly fluxes of CO and CO2 were linearly correlated to air temperature (R2 = 0.7 and 0.59 respectively); a weaker dependence upon temperature was also observed for CH4 (R2 = 0.31). Diurnal and seasonal emissions of CO and CO2 are mainly controlled by local fossil fuel combustion and vehicle cold starts are thought to account for 20-30% of additional emissions of CO during the winter. Fugitive emissions of CH4 from the natural gas distribution network are thought to be substantial, which is consistent

  19. Effects of the urban heat island on the phenology of Odonata in London, UK.

    PubMed

    Villalobos-Jiménez, Giovanna; Hassall, Christopher

    2017-02-11

    Urbanisation is one of the major drivers of ecosystem change and includes increased temperatures in cities leading to an urban heat island (UHI). This study quantified the phenological response of odonates across London, UK, from 1990 to 2012, using a database of 1,031,277 historical sightings. The ordinal flight dates of each species were used to calculate the leading edge, middle and trailing edge of the flight period (P5, P50 and P95, respectively). The results suggest that the phenology of odonates is affected by the UHI only at a community level: no significant changes in the P5 or P50 of the flight period were found, although the P95 shows a mean advance of 4.13 days compared to rural areas, thus suggesting a contraction of the flight period in urban areas. However, only one individual species (Sympetrum striolatum) exhibited an advance in the P95 of the flight period in urban areas compared to rural areas. On the other hand, climate change (minimum temperature) had a much stronger impact on the phenology of odonates at the community level with a significant advance of 6.9 days °C(-1) in the P5 of the flight period, 3.1 days °C(-1) in the P50 and 3.3 days °C(-1) in the P95 flight date. Similarly, a significant advance in P5 was found in 7 of the 15 species tested in response to minimum temperature, and 2 species showed a significant advance in P50 in response to minimum temperature, but no species showed a shift in the P95 flight date due to minimum temperature. As shown in previous studies, life history influences the phenological response of odonates, with spring species and those species lacking an egg diapause being the most responsive to increased temperatures, although summer species and species with obligate egg diapause also respond to the UHI by advancing the P95 by 3.8 and 4.5 days, respectively, compared to rural areas, thus contracting the flight period. The present study shows that the UHI has negligible impacts on emergence patterns

  20. Receptor modelling of both particle composition and size distribution from a background site in London, UK

    NASA Astrophysics Data System (ADS)

    Beddows, D. C. S.; Harrison, R. M.; Green, D. C.; Fuller, G. W.

    2015-09-01

    Positive matrix factorisation (PMF) analysis was applied to PM10 chemical composition and particle number size distribution (NSD) data measured at an urban background site (North Kensington) in London, UK, for the whole of 2011 and 2012. The PMF analyses for these 2 years revealed six and four factors respectively which described seven sources or aerosol types. These included nucleation, traffic, urban background, secondary, fuel oil, marine and non-exhaust/crustal sources. Urban background, secondary and traffic sources were identified by both the chemical composition and particle NSD analysis, but a nucleation source was identified only from the particle NSD data set. Analysis of the PM10 chemical composition data set revealed fuel oil, marine, non-exhaust traffic/crustal sources which were not identified from the NSD data. The two methods appear to be complementary, as the analysis of the PM10 chemical composition data is able to distinguish components contributing largely to particle mass, whereas the number particle size distribution data set - although limited to detecting sources of particles below the diameter upper limit of the SMPS (604 nm) - is more effective for identifying components making an appreciable contribution to particle number. Analysis was also conducted on the combined chemical composition and NSD data set, revealing five factors representing urban background, nucleation, secondary, aged marine and traffic sources. However, the combined analysis appears not to offer any additional power to discriminate sources above that of the aggregate of the two separate PMF analyses. Day-of-the-week and month-of-the-year associations of the factors proved consistent with their assignment to source categories, and bivariate polar plots which examined the wind directional and wind speed association of the different factors also proved highly consistent with their inferred sources. Source attribution according to the air mass back trajectory showed, as

  1. Pedestrian exposure to air pollution along a major road in Central London, UK

    NASA Astrophysics Data System (ADS)

    Kaur, S.; Nieuwenhuijsen, M. J.; Colvile, R. N.

    Pedestrian exposure to PM 2.5, the loss of reflectance ('blackness') of the PM 2.5 filters, ultrafine particle counts (particle range: 0.02-1 μm) and carbon monoxide (CO) was investigated along a major road running through the DAPPLE study site in Central London, UK. During an intensive 12-day exposure measurement campaign, groups of four volunteers sampled twice in the morning and twice in the afternoon along Marylebone Road. They were randomly designated a walking direction, walking position (kerbside or buildingside) and a side of the major road to walk along. PM 2.5 was sampled using high-flow gravimetric personal samplers, ultrafine particle counts were measured using TSI P-TRAKs and Langans were used to measure CO exposure. PM 2.5 samples were analysed gravimetrically and reflectance was measured using a smoke stain reflectometer to obtain a measure of 'black smoke'. In total 603 acceptable samples were obtained—155 PM 2.5 and reflectance, 120 ultrafine particle count and 173 CO. The average pedestrian exposure along the road was 37.7 μg/m 3, 12.1 m -1×10 -5, 80 009 pt/cm 3 and 1.3 ppm for PM 2.5, loss of reflectance, ultrafine particle counts and CO, respectively. PM 2.5 exposure in the morning was significantly higher than in the afternoon, and there was a significant difference in exposure on the different sides of the road. For both reflectance and ultrafine particle counts, the exposure was significantly different both between the two walking positions on the pavement and the two sides of the street canyon. However there was no significant difference in CO exposure based on walking position, walking direction, canyon side or timing. Filter reflectance was significantly but weakly correlated with PM 2.5 exposure ( r=0.3, N=155), CO exposure ( r=0.2, N=154) and ultrafine particle count exposure ( r=0.7, N=108). PM 2.5 and CO personal exposure measurements were much higher than those recorded at both the local background fixed monitoring station (FMS

  2. Effects of the urban heat island on the phenology of Odonata in London, UK

    NASA Astrophysics Data System (ADS)

    Villalobos-Jiménez, Giovanna; Hassall, Christopher

    2017-02-01

    Urbanisation is one of the major drivers of ecosystem change and includes increased temperatures in cities leading to an urban heat island (UHI). This study quantified the phenological response of odonates across London, UK, from 1990 to 2012, using a database of 1,031,277 historical sightings. The ordinal flight dates of each species were used to calculate the leading edge, middle and trailing edge of the flight period (P5, P50 and P95, respectively). The results suggest that the phenology of odonates is affected by the UHI only at a community level: no significant changes in the P5 or P50 of the flight period were found, although the P95 shows a mean advance of 4.13 days compared to rural areas, thus suggesting a contraction of the flight period in urban areas. However, only one individual species (Sympetrum striolatum) exhibited an advance in the P95 of the flight period in urban areas compared to rural areas. On the other hand, climate change (minimum temperature) had a much stronger impact on the phenology of odonates at the community level with a significant advance of 6.9 days °C-1 in the P5 of the flight period, 3.1 days °C-1 in the P50 and 3.3 days °C-1 in the P95 flight date. Similarly, a significant advance in P5 was found in 7 of the 15 species tested in response to minimum temperature, and 2 species showed a significant advance in P50 in response to minimum temperature, but no species showed a shift in the P95 flight date due to minimum temperature. As shown in previous studies, life history influences the phenological response of odonates, with spring species and those species lacking an egg diapause being the most responsive to increased temperatures, although summer species and species with obligate egg diapause also respond to the UHI by advancing the P95 by 3.8 and 4.5 days, respectively, compared to rural areas, thus contracting the flight period. The present study shows that the UHI has negligible impacts on emergence patterns of odonates

  3. [Identification of ancient Chinese medicinal specimens preserved at Natural History Museum in London].

    PubMed

    Zhao, Zhong-zhen; Zhao, Kai-cun; Brand, Eric

    2015-12-01

    On-site field investigation was conducted to authenticate a batch of ancient Chinese medicinal decoction pieces that have been preserved in a rare collection at the Natural History Museum in London. These treasured artifacts comprise a portion of the Sloane Collection, and the nearly one hundred Chinese medicinal specimens examined within provide an objective record of the real situation regarding the Chinese medicinal materials in commercial circulation three hundred years ago. The precious data from this collection pro-vides an extremely valuable reference for the research into the history of medicinal exchange between China and the West during the Age of Exploration, shedding light on the evolution and historical changes in the species used in Chinese medicine, as well as the history of medicinal processing and decoction pieces.

  4. Conference Report: Online Information Meeting 2005, Olympia, London (UK), 29 November-1 December 2005

    ERIC Educational Resources Information Center

    Education for Information, 2006

    2006-01-01

    For many years now the Holiday season has been associated with the gathering of information professionals in west London for the annual Online Information Meeting. The Meeting currently is organized by VNU Exhibitions Europe (formerly Imark Communication), though for old-timers it will forever be associated with Learned Information, the…

  5. The types of Phasmida in the Natural History Museum, London, UK.

    PubMed

    Brock, Paul D; Marshall, Judith A; Beccaloni, George W; Harman, Allan J E

    2016-10-31

    Type specimens of 437 Phasmida taxa have been located in the Natural History Museum, London (NHMUK, formerly BMNH), including 480 primary types of 372 taxa. Taxa with types are listed alphabetically by their specific or subspecific name, and the number of specimens, sex and locality data are given.

  6. Bilingual Behaviour, Attitudes, Identity and Vitality: Some Data from Japanese Speakers in London, UK

    ERIC Educational Resources Information Center

    Brown, Ivan; Sachdev, Itesh

    2009-01-01

    Although the Japanese community in London is relatively small, its composition is stable and reflects several aspects of Japan's relationship with the international community. Yet there appears to have been no systematic research exploring patterns of bilingual behaviour in relation to social psychological processes amongst Japanese nationals in…

  7. Application of MM5/CMAQ for modelling urban air pollution a case study for London, UK

    NASA Astrophysics Data System (ADS)

    Kitwiroon, N.; Fragkou, E.; Sokhi, R. S.; San Jose, R.; Pérez Camaño, J. L.; Middleton, D.

    2003-04-01

    Urban air pollution has been particularly studied for the last few decades because of its recognised environmental dangers and health implications. The complexity of the urban surface characteristics and turbulence patterns has dictated the use of numerical models by environmental research agencies and regulators in order to predict and manage urban air pollution. However, most of these models are not specifically adapted to urban applications and normally do not include detailed urban parameterisation, such as for surface roughness or urban heat fluxes. Flow structure and dispersion of air pollutants within cities, however, are influenced by urban features such as increased surface roughness. This paper presents a study using MM5 and CMAQ to assess the effect of urban boundary layer features on meteorological parameters, and hence London's air quality. MM5 is a non-hydrostatic (version 3), terrain-following sigma-coordinate model designed to simulate mesoscale and regional-scale atmospheric circulation. This paper employs an improved surface roughness treatment on meteorological profiles and pollution dispersion. A surface roughness scale has been developed for London and the surrounding region. The land cover data was derived from the Centre for Ecology and Hydrology (CEH) data, with a spatial resolution of 25 × 25 m. These z_o values are employed with MM5 for modelling meteorological parameters over London, covering an inner domain area of 49 × 49 km. The outputs of MM5 have been coupled to CMAQ photochemical model to predict concentrations of particles, NO_2 and O_3 for London and the surrounding regions at a spatial resolution of 1 × 1 km. The predicted concentrations have been compared with monitored data obtained from a range of national air quality monitoring sites including Central London (Bloomsbury, Brent), East London (Bexley) and West London (Hillingdon). Comparison of hourly model predictions with measured data is made for pollution levels for

  8. Basic life support education in secondary schools: a cross-sectional survey in London, UK

    PubMed Central

    Salciccioli, Justin D; Marshall, Dominic C; Sykes, Mark; Wood, Alexander D; Joppa, Stephanie A; Sinha, Madhurima; Lim, P Boon

    2017-01-01

    Objectives Basic life support (BLS) training in schools is associated with improved outcomes from cardiac arrest. International consensus statements have recommended universal BLS training for school-aged children. The current practice of BLS training in London schools is unknown. The aim of this study was to assess current practices of BLS training in London secondary schools. Setting, population and outcomes A prospective audit of BLS training in London secondary schools was conducted. Schools were contacted by email, and a subsequent telephone interview was conducted with staff familiar with local training practices. Response data were anonymised and captured electronically. Universal training was defined as any programme which delivers BLS training to all students in the school. Descriptive statistics were used to summarise the results. Results A total of 65 schools completed the survey covering an estimated student population of 65 396 across 19 of 32 London boroughs. There were 5 (8%) schools that provide universal training programmes for students and an additional 31 (48%) offering training as part of an extracurricular programme or chosen module. An automated external defibrillator (AED) was available in 18 (28%) schools, unavailable in 40 (61%) and 7 (11%) reported their AED provision as unknown. The most common reasons for not having a universal BLS training programme are the requirement for additional class time (28%) and that funding is unavailable for such a programme (28%). There were 5 students who died from sudden cardiac arrest over the period of the past 10 years. Conclusions BLS training rates in London secondary schools are low, and the majority of schools do not have an AED available in case of emergency. These data highlight an opportunity to improve BLS training and AEDs provision. Future studies should assess programmes which are cost-effective and do not require significant amounts of additional class time. PMID:28062467

  9. Working with Secondary School Leadership in a Large-Scale Reform in London, UK: Consultants' Perspectives of Their Role as Agents of School Change and Improvement

    ERIC Educational Resources Information Center

    Cameron, David Hagen

    2010-01-01

    This article uses a cultural and political theoretical framework to examine the relationship between consultants and secondary school leaders within a large-scale consultancy-based reform, the Secondary National Strategy (SNS), in London UK. The SNS follows a cascade model of implementation, in which nationally created initiatives are introduced…

  10. Implementation of an improved urban parametrisation into the mesoscale meteorology model METRAS and application to London, UK

    NASA Astrophysics Data System (ADS)

    Grawe, D.; Thompson, H. L.; Salmond, J.; Cai, X.-M.; Schluenzen, K. H.

    2009-09-01

    Urban areas have well documented effects on thermal and dynamic properties of the air as well as its chemical composition. E.g. increased heat storage, anthropogenic heat sources and radiative trapping can cause increased temperatures in the urban canopy, leading to an urban heat island with potentially adverse effects on human health and comfort. A nocturnal heat island may exacerbate the impact of summer heat waves. With growing urbanisation and in a changing climate it can be expected that these effects will increase. In order to mitigate adverse effects of the urban heat island, the strength of the heat island needs to be assessed for current levels of urbanisation, as well as for prospective urbanisation scenarios. For this purpose, the mesoscale meteorology model METRAS (Schlünzen, 2003) has been extended by the urban canopy model BEP (Martilli et al., 2002), which has previously been validated and implemented in other mesoscale meteorology models. BEP parameterises the effects of the urban canopy walls and surfaces on momentum, heat and turbulent kinetic energy and takes into account very detailed specifications of building parameters, such as building height distributions and street axis orientations. The implementation of BEP in METRAS allows the use of a separate numerical grid for BEP, so that for the model simulations presented in this study a very fine vertical grid with 5m cell height (compared to 20m in the METRAS grid) could be used. Greater London forms the largest urban area within the UK and has therefore been selected as the focus area for the validation of results from the improved model and for selected case studies. A domain covering 100km x 100km around London has been set up with a horizontal grid resolution of 1km x 1km. Results of the validation show that the inclusion of BEP improves the performance of METRAS for most cases when compared with measurements in the urban area. This improvement can ultimately be used to provide better

  11. Spatial and temporal variability of urban fluxes of methane, carbon monoxide and carbon dioxide above London, UK

    NASA Astrophysics Data System (ADS)

    Helfter, Carole; Tremper, Anja H.; Halios, Christoforos H.; Kotthaus, Simone; Bjorkegren, Alex; Grimmond, C. Sue B.; Barlow, Janet F.; Nemitz, Eiko

    2016-08-01

    We report on more than 3 years of measurements of fluxes of methane (CH4), carbon monoxide (CO) and carbon dioxide (CO2) taken by eddy-covariance in central London, UK. Mean annual emissions of CO2 in the period 2012-2014 (39.1 ± 2.4 ktons km-2 yr-1) and CO (89 ± 16 tons km-2 yr-1) were consistent (within 1 and 5 % respectively) with values from the London Atmospheric Emissions Inventory, but measured CH4 emissions (72 ± 3 tons km-2 yr-1) were over two-fold larger than the inventory value. Seasonal variability was large for CO with a winter to summer reduction of 69 %, and monthly fluxes were strongly anti-correlated with mean air temperature. The winter increment in CO emissions was attributed mainly to vehicle cold starts and reduced fuel combustion efficiency. CO2 fluxes were 33 % higher in winter than in summer and anti-correlated with mean air temperature, albeit to a lesser extent than for CO. This was attributed to an increased demand for natural gas for heating during the winter. CH4 fluxes exhibited moderate seasonality (21 % larger in winter), and a spatially variable linear anti-correlation with air temperature. Differences in resident population within the flux footprint explained up to 90 % of the spatial variability of the annual CO2 fluxes and up to 99 % for CH4. Furthermore, we suggest that biogenic sources of CH4, such as wastewater, which is unaccounted for by the atmospheric emissions inventories, make a substantial contribution to the overall budget and that commuting dynamics in and out of central business districts could explain some of the spatial and temporal variability of CO2 and CH4 emissions. To our knowledge, this study is unique given the length of the data sets presented, especially for CO and CH4 fluxes. This study offers an independent assessment of "bottom-up" emissions inventories and demonstrates that the urban sources of CO and CO2 are well characterized in London. This is however not the case for CH4 emissions which are

  12. Complaints about dog faeces as a symbolic representation of incivility in London, UK: a qualitative study.

    PubMed

    Derges, Jane; Lynch, Rebecca; Clow, Angela; Petticrew, Mark; Draper, Alizon

    2012-12-01

    During a 'Well London' study, residents were asked about their neighbourhood and its environment. Above all other complaints, 'dog poo' was mentioned as a key concern. Despite low rates of infection and disease among the human population resulting from contact with canine faecal matter, the concerns of the public continue to rate it as a serious public health issue. Most public health studies, therefore, seek to identify processes of transmission and disease pathology as a method of addressing the problem. This study approaches the issue through a contextualised analysis of residents' complaints, using anthropological theory to examine the symbolic representation of 'dog poo'. Analysis of the interviews shows that these specific complaints were located among less easily defined or articulated experiences of social and environmental neglect, where neighbours were estranged from one another and local authorities seen as negligent. This approach has important implications for public health, as it provides not only a strong indicator of the level of dissatisfaction within some of London's more disadvantaged neighbourhoods, but also identifies a need for policies that are grounded in cross-disciplinary research into the relationship between health, 'wellbeing' and experiences of marginalisation among urban populations.

  13. HIV-related discrimination reported by people living with HIV in London, UK.

    PubMed

    Elford, Jonathan; Ibrahim, Fowzia; Bukutu, Cecilia; Anderson, Jane

    2008-03-01

    The objective was to examine the extent to which people living with HIV in London reported being discriminated against because of their infection. In 2004-2005, people living with HIV attending NHS outpatient HIV clinics in north east London were asked: "Have you ever been treated unfairly or differently because of your HIV status-in other words discriminated against?". Of the 1,687 people who returned a questionnaire (73% response rate), data from 1,385 respondents were included in this analysis; 448 heterosexual women and 210 heterosexual men of black African origin, 727 gay/bisexual men (621 white, 106 ethnic minority). Overall, nearly one-third of respondents (29.9%, 414/1,385) said they had been discriminated against because of their HIV infection. Of those who reported experiencing HIV-related discrimination, almost a half (49.6%, 200/403) said this had involved a health care worker including their dentist (n = 102, 25.3%) or primary care physician (n = 70, 17.4%).

  14. Environmental Risk Factors influencing Bicycle Theft: A Spatial Analysis in London, UK.

    PubMed

    Mburu, Lucy Waruguru; Helbich, Marco

    2016-01-01

    Urban authorities are continuously drawing up policies to promote cycling among commuters. However, these initiatives are counterproductive for the targeted objectives because they increase opportunities for bicycle theft. This paper explores Inner London as a case study to address place-specific risk factors for bicycle theft at the street-segment level while controlling for seasonal variation. The presence of certain public amenities (e.g., bicycle stands, railway stations, pawnshops) was evaluated against locations of bicycle theft between 2013 and 2016 and risk effects were estimated using negative binomial regression models. Results showed that a greater level of risk stemmed from land-use facilities than from area-based socioeconomic status. The presence of facilities such as train stations, vacant houses, pawnbrokers and payday lenders increased bicycle theft, but no evidence was found that linked police stations with crime levels. The findings have significant implications for urban crime prevention with respect to non-residential land use.

  15. Environmental Risk Factors influencing Bicycle Theft: A Spatial Analysis in London, UK

    PubMed Central

    Helbich, Marco

    2016-01-01

    Urban authorities are continuously drawing up policies to promote cycling among commuters. However, these initiatives are counterproductive for the targeted objectives because they increase opportunities for bicycle theft. This paper explores Inner London as a case study to address place-specific risk factors for bicycle theft at the street-segment level while controlling for seasonal variation. The presence of certain public amenities (e.g., bicycle stands, railway stations, pawnshops) was evaluated against locations of bicycle theft between 2013 and 2016 and risk effects were estimated using negative binomial regression models. Results showed that a greater level of risk stemmed from land-use facilities than from area-based socioeconomic status. The presence of facilities such as train stations, vacant houses, pawnbrokers and payday lenders increased bicycle theft, but no evidence was found that linked police stations with crime levels. The findings have significant implications for urban crime prevention with respect to non-residential land use. PMID:27643788

  16. Highlights from Faraday Discussion: Designing New Heterogeneous Catalysts, London, UK, April 2016.

    PubMed

    Fischer, Nico; Manyar, Haresh G; Roldan, Alberto

    2016-06-28

    The Faraday Discussion on the design of new heterogeneous catalysts took place from 4-6 April 2016 in London, United Kingdom. It brought together world leading scientists actively involved in the synthesis, characterisation, modelling and testing of solid catalysts, attracting more than one hundred delegates from a broad spectrum of backgrounds and experience levels - academic and industrial researchers, experimentalists and theoreticians, and students. The meeting was a reflection of how big of an impact the ability to control and design catalysts with specific properties for particular processes can potentially have on the chemical industry, environment, economy and society as a whole. In the following, we give an overview of the topics covered during this meeting and briefly highlight the content of each presentation.

  17. Discovery of previously unrecognised local faults in London, UK, using detailed 3D geological modelling

    NASA Astrophysics Data System (ADS)

    Aldiss, Don; Haslam, Richard

    2013-04-01

    In parts of London, faulting introduces lateral heterogeneity to the local ground conditions, especially where construction works intercept the Palaeogene Lambeth Group. This brings difficulties to the compilation of a ground model that is fully consistent with the ground investigation data, and so to the design and construction of engineering works. However, because bedrock in the London area is rather uniform at outcrop, and is widely covered by Quaternary deposits, few faults are shown on the geological maps of the area. This paper discusses a successful resolution of this problem at a site in east central London, where tunnels for a new underground railway station are planned. A 3D geological model was used to provide an understanding of the local geological structure, in faulted Lambeth Group strata, that had not been possible by other commonly-used methods. This model includes seven previously unrecognised faults, with downthrows ranging from about 1 m to about 12 m. The model was constructed in the GSI3D geological modelling software using about 145 borehole records, including many legacy records, in an area of 850 m by 500 m. The basis of a GSI3D 3D geological model is a network of 2D cross-sections drawn by a geologist, generally connecting borehole positions (where the borehole records define the level of the geological units that are present), and outcrop and subcrop lines for those units (where shown by a geological map). When the lines tracing the base of each geological unit within the intersecting cross-sections are complete and mutually consistent, the software is used to generate TIN surfaces between those lines, so creating a 3D geological model. Even where a geological model is constructed as if no faults were present, changes in apparent dip between two data points within a single cross-section can indicate that a fault is present in that segment of the cross-section. If displacements of similar size with the same polarity are found in a series

  18. Challenges of monitoring use of secondary care at local level: a study based in London, UK.

    PubMed Central

    Chenet, L; McKee, M

    1996-01-01

    STUDY OBJECTIVE: To provide those working at district level with practical guidance on using hospital data linked to small geographic areas to explore patterns of care. DESIGN: Examination of the association between age standardised hospital episode rates for the commonest diagnostic categories and deprivation levels (Carstairs index) of the electoral ward of residence. SETTING: An inner London district, Kensington, Chelsea and Westminster, with a population of approximately 325,000. POPULATION: All finished consultant episodes recorded in NHS hospitals for the district population in the year to April 1994. MAIN RESULTS: Many, but not all, disease categories were associated strongly with deprivation, with high episode rates in the most deprived electoral wards. This is partly due to more of those in deprived areas being admitted to hospital and to them being admitted more often. CONCLUSIONS: A wide range of factors needs to be taken into account in interpreting these data. They include the contribution of the private sector and artifacts of both the numerator and denominator. This paper provides a framework for those working at district level to begin to analyse the association between hospitalisation and deprivation locally. It also identifies some of the issues that must be taken into account when seeking to interpret these data. PMID:8935471

  19. Short-term exposure to traffic-related air pollution and daily mortality in London, UK.

    PubMed

    Atkinson, Richard W; Analitis, Antonis; Samoli, Evangelia; Fuller, Gary W; Green, David C; Mudway, Ian S; Anderson, Hugh R; Kelly, Frank J

    2016-01-01

    Epidemiological studies have linked daily concentrations of urban air pollution to mortality, but few have investigated specific traffic sources that can inform abatement policies. We assembled a database of >100 daily, measured and modelled pollutant concentrations characterizing air pollution in London between 2011 and 2012. Based on the analyses of temporal patterns and correlations between the metrics, knowledge of local emission sources and reference to the existing literature, we selected, a priori, markers of traffic pollution: oxides of nitrogen (general traffic); elemental and black carbon (EC/BC) (diesel exhaust); carbon monoxide (petrol exhaust); copper (tyre), zinc (brake) and aluminium (mineral dust). Poisson regression accounting for seasonality and meteorology was used to estimate the percentage change in risk of death associated with an interquartile increment of each pollutant. Associations were generally small with confidence intervals that spanned 0% and tended to be negative for cardiovascular mortality and positive for respiratory mortality. The strongest positive associations were for EC and BC adjusted for particle mass and respiratory mortality, 2.66% (95% confidence interval: 0.11, 5.28) and 2.72% (0.09, 5.42) per 0.8 and 1.0 μg/m(3), respectively. These associations were robust to adjustment for other traffic metrics and regional pollutants, suggesting a degree of specificity with respiratory mortality and diesel exhaust containing EC/BC.

  20. Entitlement to concessionary public transport and wellbeing: a qualitative study of young people and older citizens in London, UK.

    PubMed

    Jones, Alasdair; Goodman, Anna; Roberts, Helen; Steinbach, Rebecca; Green, Judith

    2013-08-01

    Access to transport is an important determinant of health, and concessionary fares for public transport are one way to reduce the 'transport exclusion' that can limit access. This paper draws on qualitative data from two groups typically at risk of transport exclusion: young people (12-18 years of age, n = 118) and older citizens (60+ years of age, n = 46). The data were collected in London, UK, where young people and older citizens are currently entitled to concessionary bus travel. We focus on how this entitlement is understood and enacted, and how different sources of entitlement mediate the relationship between transport and wellbeing. Both groups felt that their formal entitlement to travel for free reflected their social worth and was, particularly for older citizens, relatively unproblematic. The provision of a concessionary transport entitlement also helped to combat feelings of social exclusion by enhancing recipients' sense of belonging to the city and to a 'community'. However, informal entitlements to particular spaces on the bus reflected less valued social attributes such as need or frailty. Thus in the course of travelling by bus the enactment of entitlements to space and seats entailed the negotiation of social differences and personal vulnerabilities, and this carried with it potential threats to wellbeing. We conclude that the process, as well as the substance, of entitlement can mediate wellbeing; and that where the basis for providing a given entitlement is widely understood and accepted, the risks to wellbeing associated with enacting that entitlement will be reduced.

  1. How and Why Do Smokers Start Using E-Cigarettes? Qualitative Study of Vapers in London, UK

    PubMed Central

    Wadsworth, Elle; Neale, Joanne; McNeill, Ann; Hitchman, Sara C.

    2016-01-01

    The aims of the study were to (1) describe how and why smokers start to vape and what products they use; (2) relate findings to the COM-B theory of behaviour change (three conditions are necessary for behaviour change (B): capability (C), opportunity (O), and motivation (M)); and (3) to consider implications for e-cigarette policy research. Semi-structured interviews (n = 30) were conducted in London, UK, with smokers or ex-smokers who were currently using or had used e-cigarettes. E-cigarette initiation (behaviour) was facilitated by: capability (physical capability to use an e-cigarette and psychological capability to understand that using e-cigarettes was less harmful than smoking); opportunity (physical opportunity to access e-cigarettes in shops, at a lower cost than cigarettes, and to vape in “smoke-free” environments, as well as social opportunity to vape with friends and family); and motivation (automatic motivation including curiosity, and reflective motivation, including self-conscious decision-making processes related to perceived health benefits). The application of the COM-B model identified multiple factors that may lead to e-cigarette initiation, including those that could be influenced by policy, such as price relative to cigarettes and use in smoke-free environments. The effects of these policies on initiation should be further investigated along with the possible moderating/mediating effects of social support. PMID:27376312

  2. Liminal identities: Caribbean men who have sex with men in London, UK.

    PubMed

    Anderson, Moji; Elam, Gillian; Gerver, Sarah; Solarin, Ijeoma; Fenton, Kevin; Easterbrook, Phillippa

    2009-04-01

    Accounts by 10 Caribbean men who have sex with men living in the UK reveal them to be liminal beings with unstable and unresolved identities. They are between social states: aware they are not heterosexual and not publicly recognised, or in some cases self-accepted, as homosexual. Caribbean-born respondents especially suffer from homophobia, expressing regret and disappointment at their sexuality. They may also experience cognitive dissonance - as they are aware of their conflict with the heteronormative order - they cannot resolve. Religion contributes to homophobia and cognitive dissonance particularly for Caribbean-born men, some of whom may believe a fundamental conflict exists between Christianity and homosexuality. Heterosexism and homophobia contribute to and reinforce their liminal state, by preventing transition to publicly recognised homosexual status. Respondents may engage in private and public, internal and external, overt and covert policing of their and other gay men's behaviour: through strategic pretence at heterosexuality and/or condemnation of men engaging in behaviour identifiable as stereotypically homosexual, for example. Narratives point to the need to complexify the conventional understanding of Jamaican heterosexism to explain reported variations in the degree of anti-homosexual hostility in the country.

  3. Seven years of teenage pregnancy in an inner London genitourinary medicine service - a retrospective cohort study.

    PubMed

    Hegazi, Aseel; Daley, Natalie; Williams, Elizabeth; McLeod, Felicity; Rafiezadeh, Saba; Prime, Katia

    2014-12-01

    Young people attending genitourinary medicine services are at high risk of unplanned pregnancy. We performed a retrospective cohort study to identify characteristics of pregnant teenagers accessing an inner London genitourinary medicine service. There were 481 pregnancies in 458 teenagers with 54 previous pregnancies and 46 previous terminations of pregnancy. The under-18 and under-16 teenage pregnancy rates were 92.1 and 85.8 per 1000 age-matched clinic attendees, respectively. Median age was 17.1 years. 'Black Other' teenagers ('Black British', 'Mixed White-Black Caribbean' and 'Mixed White-Black African') were over-represented, compared to our clinic population, while those of White ethnicity were under-represented. Few pregnancies (1.5%) were planned with the majority (64%) intending terminations of pregnancy. Most teenagers did not use consistent contraception. Two-thirds of patients had attended genitourinary medicine services in the past and sexually transmitted infection prevalence at presentation was high. Effectively targeting the sexual and reproductive health needs of teenage genitourinary medicine clinic attendees may have a significant impact on reducing sexually transmitted infections, unplanned pregnancy and terminations of pregnancy in this group.

  4. Methanotrophy in London, UK, Landfill Topsoil: Microbiology, Stable Carbon Isotopes, Seasonal Variation and Laboratory Model Study

    NASA Astrophysics Data System (ADS)

    Sriskantharajah, S.; Fisher, R.; Lowry, D.; Grassineau, N.; Nisbet, E. G.

    2004-12-01

    Landfill is a major source of methane emissions into the atmosphere. Aerobic soil is also a good sink of methane, as it is inhabited by methane consuming bacteria, methanotrophs. Methanotrophic bacteria were cultured from landfill soil samples. Three genera of methanotrophs were cultured: Methylocaldum, Methylosinus and Methylomonas. Interestingly, the only established members of the Methylocaldum genus are all thermophilic, whilst those isolated in this study are mesophilic. This suggests that those Methylocaldum methanotrophs found in landfills may have migrated from hot spring natural settings. Representatives of each genera were inoculated into a simple topsoil model and subjected to variations in temperature, methane concentration and incubation periods. As expected, temperature greatly affected methane oxidation, but methane concentration affected the rate of oxidation far more than expected. The model study implies that the complete combustion of methane to carbon dioxide is greatly affected by temperature and methane availability, whilst the effect on the uptake of methane is not as great. Seasonal variations in methane concentrations within the topsoil were monitored over a one year period from November 2002 to October 2003 and show that methane flow through the topsoil, and consequently methanotrophy, is strongly controlled by meteorology, mainly air temperature and pressure. Generally, methanotrophy was low during colder months and higher at during warmer months, but changes in air pressure complicate this by controlling the rate of flow of methane through the topsoil. δ 13C analyses of methane and carbon dioxide emitted from landfill topsoil showed that there was a great deal of methanotrophic activity during the warmer months of 2003, with most fractionation of residual methane occurring during August. During the heat wave experienced in the UK in August 2003, the δ 13C from borehole samples of methane in the anaerobic zone shifted from -57‰ to -16

  5. Prevalence, determinants and clinical correlates of vitamin D deficiency in adults with inhaled corticosteroid-treated asthma in London, UK.

    PubMed

    Jolliffe, David A; Kilpin, Kate; MacLaughlin, Beverley D; Greiller, Claire L; Hooper, Richard L; Barnes, Neil C; Timms, Peter M; Rajakulasingam, Raj K; Bhowmik, Angshu; Choudhury, Aklak B; Simcock, David E; Hyppönen, Elina; Corrigan, Christopher J; Walton, Robert T; Griffiths, Christopher J; Martineau, Adrian R

    2016-11-05

    Vitamin D deficiency is common in children with asthma, and it associates with poor asthma control, reduced forced expiratory volume in one second (FEV1) and increased requirement for inhaled corticosteroids (ICS). Cross-sectional studies investigating the prevalence, determinants and clinical correlates of vitamin D deficiency in adults with asthma are lacking. We conducted a multi-centre cross-sectional study in 297 adults with a medical record diagnosis of ICS-treated asthma living in London, UK. Details of potential environmental determinants of vitamin D status, asthma control and medication use were collected by questionnaire; blood samples were taken for analysis of serum 25(OH)D concentration and DNA extraction, and participants underwent measurement of weight, height and fractional exhaled nitric oxide concentration (FeNO), spirometry and sputum induction for determination of lower airway eosinophil counts (n=35 sub-group). Thirty-five single nucleotide polymorphisms (SNP) in 11 vitamin D pathway genes (DBP, DHCR7, RXRA, CYP2R1, CYP27B1, CYP24A1, CYP3A4 CYP27A1, LRP2, CUBN, VDR) were typed using Taqman allelic discrimination assays. Linear regression was used to identify environmental and genetic factors independently associated with serum 25(OH)D concentration, and to determine whether vitamin D status was independently associated with Asthma Control Test (ACT) score, ICS dose, FeNO, forced vital capacity (FVC), FEV1 or lower airway eosinophilia. Mean serum 25(OH)D concentration was 50.6nmol/L (SD 24.9); 162/297 (54.5%) participants were vitamin D deficient (serum 25(OH)D concentration <50nmol/L). Lower vitamin D status was associated with higher body mass index (P=0.014), non-White ethnicity (P=0.036), unemployment (P for trend=0.012), lack of vitamin D supplement use (P<0.001), sampling in Winter or Spring (P for trend <0.001) and lack of a recent sunny holiday abroad (P=0.030), but not with potential genetic determinants. Vitamin D status was not found

  6. Antibiotic resistance and mecA characterization of coagulase-negative staphylococci isolated from three hotels in London, UK.

    PubMed

    Xu, Zhen; Mkrtchyan, Hermine V; Cutler, Ronald R

    2015-01-01

    Antibiotic resistance in bacteria isolated from non-healthcare environments, is a potential problem to public health. In our survey a total of 71 coagulase negative staphylococci (CNS) belonging to 11 different species were isolated from three large hotels in London, UK. The most prevalent species was Staphylococcus haemolyticus, with S. hominis, S. warneri, S. cohnii, and Staphylococcus epidermidis commonly detected. Antimicrobial susceptibilities and carriage of the mecA gene were determined for all of these isolates. Most (85.9%) staphylococci were resistant to multiple antibiotics with all displaying increased susceptibility toward penicillin, fusidic acid, erythromycin, and cefepime. Twenty-one (29.5%) of the isolates were mecA positive, however MIC values to oxacillin, normally associated with the carriage of mecA, varied widely in this group (from 0.06 to 256 mg/L). Fifteen of the twenty-one mecA positive isolates carried SCCmec of these seven were type V, one type I, one type II, and one type IV. Additionally, five of these 15 isolates carried a previously unreported type, 1A, which involves an association between class A mec complex and ccr type 1. The remaining six of the 21 isolates were non-typeable and carried a combination of class A mec complex and ccrC. In addition to this, we also report on new MLST types which were assigned for five S. epidermidis isolates. Four out of these five isolates had MICs between 0.06 and 256 mg/L to oxacillin and would be regarded as clinically susceptible but one isolate had a high oxacillin MIC of 256 mg/L. We demonstrated widespread multiple drug resistance among different staphylococcal species isolated from non-healthcare environments highlighting the potential for these species to act as a reservoir for methicillin and other forms of drug resistance.

  7. Prevalence, determinants and clinical correlates of vitamin D deficiency in patients with Chronic Obstructive Pulmonary Disease in London, UK.

    PubMed

    Jolliffe, David A; James, Wai Yee; Hooper, Richard L; Barnes, Neil C; Greiller, Claire L; Islam, Kamrul; Bhowmik, Angshu; Timms, Peter M; Rajakulasingam, Raj K; Choudhury, Aklak B; Simcock, David E; Hyppönen, Elina; Walton, Robert T; Corrigan, Christopher J; Griffiths, Christopher J; Martineau, Adrian R

    2017-02-01

    Vitamin D deficiency is common in patients with chronic obstructive pulmonary disease (COPD), yet a comprehensive analysis of environmental and genetic determinants of serum 25-hydroxyvitamin D (25[OH]D) concentration in patients with this condition is lacking. We conducted a multi-centre cross-sectional study in 278 COPD patients aged 41-92 years in London, UK. Details of potential environmental determinants of vitamin D status and COPD symptom control and severity were collected by questionnaire, and blood samples were taken for analysis of serum 25(OH)D concentration and DNA extraction. All participants performed spirometry and underwent measurement of weight and height. Quadriceps muscle strength (QS) was measured in 134 participants, and sputum induction with enumeration of lower airway eosinophil and neutrophil counts was performed for 44 participants. Thirty-seven single nucleotide polymorphisms (SNP) in 11 genes in the vitamin D pathway (DBP, DHCR7, CYP2R1, CYP27B1, CYP24A1, CYP27A1, CYP3A4, LRP2, CUBN, RXRA, and VDR) were typed using Taqman allelic discrimination assays. Linear regression was used to identify environmental and genetic factors independently associated with serum 25(OH)D concentration and to determine whether vitamin D status or genetic factors independently associated with % predicted forced expiratory volume in one second (FEV1), % predicted forced vital capacity (FVC), the ratio of FEV1 to FVC (FEV1:FVC), daily inhaled corticosteroid (ICS) dose, respiratory quality of life (QoL), QS, and the percentage of eosinophils and neutrophils in induced sputum. Mean serum 25(OH)D concentration was 45.4nmol/L (SD 25.3); 171/278 (61.5%) participants were vitamin D deficient (serum 25[OH]D concentration <50nmol/L). Lower vitamin D status was independently associated with higher body mass index (P=0.001), lower socio-economic position (P=0.037), lack of vitamin D supplement consumption (P<0.001), sampling in Winter or Spring (P for trend=0.006) and

  8. Pharmaceutical Pricing and Market Access Outlook Europe 2010-HealthNetwork Communications' fourth annual conference. 24-25 March 2010, London, UK.

    PubMed

    Ogbighele, Erhimuvi

    2010-05-01

    The HealthNetwork Communications' Fourth Annual Conference on Pharmaceutical Pricing and Market Access Outlook Europe 2010, held in London, included topics covering the challenges facing the pharmaceutical industry, specifically related to pricing and reimbursement, and demonstrating the value of a pharmaceutical. This conference report highlights selected presentations on a global perspective on pricing and reimbursement, with an analysis of the specific, unique challenges in the six major markets, Europe, the US, Canada, Germany, the UK and Japan, and a discussion of the benefits of risk-sharing schemes.

  9. Are fuel poverty reduction schemes associated with decreased excess winter mortality in elders? A case study from London, U.K.

    PubMed

    El Ansari, Walid; El-Silimy, Sally

    2008-12-01

    The London Borough of Newham, London piloted the Warm Zone, a government-led fuel poverty reduction scheme. Fuel poverty is often cited as a factor in excess winter mortality (EWM) in the U.K. This study reported in this paper assessed whether EWM decreased for people aged > or =65 years in Newham as compared to all London, employing data from before and throughout the duration of the Warm Zone project. The paper also discusses the difficulties surrounding the measurement and interpretation of health impact relating to fuel poverty. We calculated and compared the yearly EWM indices for people aged > or =65 years for all of London, and for Newham over 12 years (1993-2005). The yearly EWM ratio for Newham in relation to all London was then calculated and compared. No definitive evidence to support the effect of the War Zone on EMW were noted. Relationships between EWM and fewer poverty reduction schemes are difficult to interpret, as many factors are entangled. These include cold strain and biological, genetic, gender, physiological, thermoregulation, environmental, meteorological, socio-economic, healthcare provision/expenditure, lifestyle and co-morbidity aspects, besides the challenges of sample sizes and whether other fuel poverty reduction schemes were simultaneously in operation. Those in privately owned housing might be ;masked' (underestimated) in their vulnerability to fuel poverty. Redefining the specific criteria for eligibility for fuel poverty grants and tackling heat inefficiency in privately owned homes not eligible for home heating improvement despite fulfilling other criteria for vulnerability requires attention. The implications are discussed.

  10. Model simulations of cooking organic aerosol (COA) over the UK using estimates of emissions based on measurements at two sites in London

    NASA Astrophysics Data System (ADS)

    Ots, Riinu; Vieno, Massimo; Allan, James D.; Reis, Stefan; Nemitz, Eiko; Young, Dominique E.; Coe, Hugh; Di Marco, Chiara; Detournay, Anais; Mackenzie, Ian A.; Green, David C.; Heal, Mathew R.

    2016-11-01

    Cooking organic aerosol (COA) is currently not included in European emission inventories. However, recent positive matrix factorization (PMF) analyses of aerosol mass spectrometer (AMS) measurements have suggested important contributions of COA in several European cities. In this study, emissions of COA were estimated for the UK, based on hourly AMS measurements of COA made at two sites in London (a kerbside site in central London and an urban background site in a residential area close to central London) for the full calendar year of 2012 during the Clean Air for London (ClearfLo) campaign. Iteration of COA emissions estimates and subsequent evaluation and sensitivity experiments were conducted with the EMEP4UK atmospheric chemistry transport modelling system with a horizontal resolution of 5 km × 5 km. The spatial distribution of these emissions was based on workday population density derived from the 2011 census data. The estimated UK annual COA emission was 7.4 Gg per year, which is an almost 10 % addition to the officially reported UK national total anthropogenic emissions of PM2.5 (82 Gg in 2012), corresponding to 320 mg person-1 day-1 on average. Weekday and weekend diurnal variation in COA emissions were also based on the AMS measurements. Modelled concentrations of COA were then independently evaluated against AMS-derived COA measurements from another city and time period (Manchester, January-February 2007), as well as with COA estimated by a chemical mass balance model of measurements for a 2-week period at the Harwell rural site (˜ 80 km west of central London). The modelled annual average contribution of COA to ambient particulate matter (PM) in central London was between 1 and 2 µg m-3 (˜ 20 % of total measured OA1) and between 0.5 and 0.7 µg m-3 in other major cities in England (Manchester, Birmingham, Leeds). It was also shown that cities smaller than London can have a central hotspot of population density of smaller

  11. King’s College London, a cardiac centre of excellence: will it only be possible to deliver the best cardiovascular medicine in 'capital cities' in the future?

    PubMed

    2011-09-01

    New developments at King's College, London, suggest that the complexity of modern cardiovascular medicine, and the enormous prospects for future advances, means that smaller cities will find it hard to compete, reports Barry Shurlock, MA, PhD.

  12. Lessons for control of heroin-associated anthrax in Europe from 2009-2010 outbreak case studies, London, UK.

    PubMed

    Abbara, Aula; Brooks, Tim; Taylor, Graham P; Nolan, Marianne; Donaldson, Hugo; Manikon, Maribel; Holmes, Alison

    2014-07-01

    Outbreaks of serious infections associated with heroin use in persons who inject drugs (PWIDs) occur intermittently and require vigilance and rapid reporting of individual cases. Here, we give a firsthand account of the cases in London during an outbreak of heroin-associated anthrax during 2009-2010 in the United Kingdom. This new manifestation of anthrax has resulted in a clinical manifestation distinct from already recognized forms. During 2012-13, additional cases of heroin-associated anthrax among PWIDs in England and other European countries were reported, suggesting that anthrax-contaminated heroin remains in circulation. Antibacterial drugs used for serious soft tissue infection are effective against anthrax, which may lead to substantial underrecognition of this novel illness. The outbreak in London provides a strong case for ongoing vigilance and the use of serologic testing in diagnosis and serologic surveillance schemes to determine and monitor the prevalence of anthrax exposure in the PWID community.

  13. Lessons for Control of Heroin-Associated Anthrax in Europe from 2009–2010 Outbreak Case Studies, London, UK

    PubMed Central

    Abbara, Aula; Brooks, Tim; Taylor, Graham P.; Nolan, Marianne; Donaldson, Hugo; Manikon, Maribel

    2014-01-01

    Outbreaks of serious infections associated with heroin use in persons who inject drugs (PWIDs) occur intermittently and require vigilance and rapid reporting of individual cases. Here, we give a firsthand account of the cases in London during an outbreak of heroin-associated anthrax during 2009–2010 in the United Kingdom. This new manifestation of anthrax has resulted in a clinical manifestation distinct from already recognized forms. During 2012–13, additional cases of heroin-associated anthrax among PWIDs in England and other European countries were reported, suggesting that anthrax-contaminated heroin remains in circulation. Antibacterial drugs used for serious soft tissue infection are effective against anthrax, which may lead to substantial underrecognition of this novel illness. The outbreak in London provides a strong case for ongoing vigilance and the use of serologic testing in diagnosis and serologic surveillance schemes to determine and monitor the prevalence of anthrax exposure in the PWID community. PMID:24959910

  14. Superbugs and Superdrugs-SMi's 12th annual conference--Overcoming resistance. 17-18 March 2010, London, UK.

    PubMed

    Oni, Adekemi

    2010-05-01

    The 12th Annual Superbugs and Superdrugs conference, held in London, included topics covering new therapeutic developments in the field of antimicrobial research. This conference report highlights selected presentations on antimicrobial peptides, addressing bacterial resistance, and new treatments for bacterial infections. Investigational drugs discussed include DPK-060 (DermaGen AB), DAV-132 (Da Volterra), PF-4287881, PNU-100480 and PF-02538084 (all Pfizer Inc), BAL-30072 (Basilea Pharmaceutica International Ltd) and lanbiotics from Novacta.

  15. ‘Complex’ but coping: experience of symptoms of tuberculosis and health care seeking behaviours - a qualitative interview study of urban risk groups, London, UK

    PubMed Central

    2014-01-01

    Background Tuberculosis awareness, grounded in social cognition models of health care seeking behaviour, relies on the ability of individuals to recognise symptoms, assess their risk and access health care (passive case finding). There is scant published research into the health actions of ‘hard-to-reach’ groups with tuberculosis, who represent approximately 17% of the London TB caseload. This study aimed to analyse patients’ knowledge of tuberculosis, their experiences of symptoms and their health care seeking behaviours. Methods Qualitative interviews were conducted with 17 participants, predominantly homeless and attending a major tuberculosis centre in London, UK. Most had complex medical and social needs including drug and alcohol use or immigration problems affecting entitlement to social welfare. Analytical frameworks aimed to reflect the role of broader social structures in shaping individual health actions. Results Although participants demonstrated some knowledge of tuberculosis their awareness of personal risk was low. Symptoms commonly associated with tuberculosis were either not recognised or were attributed to other causes for which participants would not ordinarily seek health care. Many accessed health care by chance and, for some, for health concerns other than tuberculosis. Conclusions Health education, based on increasing awareness of symptoms, may play a limited role in tuberculosis care for populations with complex health and social needs. The findings support the intensification of outreach initiatives to identify groups at risk of tuberculosis and the development of structured care pathways which support people into prompt diagnosis and treatment. PMID:24943308

  16. Estimating the influence of different urban canopy cover types on atmospheric particulate matter (PM10) pollution abatement in London UK.

    NASA Astrophysics Data System (ADS)

    Tallis, Matthew; Freer-Smith, Peter; Sinnett, Danielle; Aylott, Matthew; Taylor, Gail

    2010-05-01

    In the urban environment atmospheric pollution by PM10 (particulate matter with a diameter less than 10 x 10-6 m) is a problem that can have adverse effects on human health, particularly increasing rates of respiratory disease. The main contributors to atmospheric PM10 in the urban environment are road traffic, industry and power production. The urban tree canopy is a receptor for removing PM10s from the atmosphere due to the large surface areas generated by leaves and air turbulence created by the structure of the urban forest. In this context urban greening has long been known as a mechanism to contribute towards PM10 removal from the air, furthermore, tree canopy cover has a role in contributing towards a more sustainable urban environment. The work reported here has been carried out within the BRIDGE project (SustainaBle uRban plannIng Decision support accountinG for urban mEtabolism). The aim of this project is to assess the fluxes of energy, water, carbon dioxide and particulates within the urban environment and develope a DSS (Decision Support System) to aid urban planners in sustainable development. A combination of published urban canopy cover data from ground, airborne and satellite based surveys was used. For each of the 33 London boroughs the urban canopy was classified to three groups, urban woodland, street trees and garden trees and each group quantified in terms of ground cover. The total [PM10] for each borough was taken from the LAEI (London Atmospheric Emissions Inventory 2006) and the contribution to reducing [PM10] was assessed for each canopy type. Deposition to the urban canopy was assessed using the UFORE (Urban Forest Effects Model) approach. Deposition to the canopy, boundary layer height and percentage reduction of the [PM10] in the atmosphere was assessed using both hourly meterological data and [PM10] and seasonal data derived from annual models. Results from hourly and annual data were compared with measured values. The model was then

  17. Trust, autonomy and relationships: the help-seeking preferences of young people in secondary level schools in London (UK).

    PubMed

    Leavey, Gerard; Rothi, Despina; Paul, Rini

    2011-08-01

    Help-seeking among young people is complicated, often determined vicariously by the ability of adults, family or professionals, to recognize, and respond to, their difficulties. We know very little about the complex concerns of teenage young people and how they impact on help-seeking preferences. We aimed to ascertain the help-seeking preferences for a range of mental health problems among adolescents attending schools in an inner-city area of London. In particular we sought to examine the relationship between such adolescents and their family doctor. Using a mixed methods approach we explored help-seeking attitudes of young people. Emotional and mental health problems are not seen by young people as the domain of General practitioners. Moreover, there is a worrying lack of confidence and trust placed in family doctor and other professionals by young people. Young people do not tend easily to trust adults to help them with emotional difficulties.

  18. Evaluation of the source area of rooftop scalar measurements in London, UK using wind tunnel and modelling approaches.

    NASA Astrophysics Data System (ADS)

    Brocklehurst, Aidan; Boon, Alex; Barlow, Janet; Hayden, Paul; Robins, Alan

    2014-05-01

    The source area of an instrument is an estimate of the area of ground over which the measurement is generated. Quantification of the source area of a measurement site provides crucial context for analysis and interpretation of the data. A range of computational models exists to calculate the source area of an instrument, but these are usually based on assumptions which do not hold for instruments positioned very close to the surface, particularly those surrounded by heterogeneous terrain i.e. urban areas. Although positioning instrumentation at higher elevation (i.e. on masts) is ideal in urban areas, this can be costly in terms of installation and maintenance costs and logistically difficult to position instruments in the ideal geographical location. Therefore, in many studies, experimentalists turn to rooftops to position instrumentation. Experimental validations of source area models for these situations are very limited. In this study, a controlled tracer gas experiment was conducted in a wind tunnel based on a 1:200 scale model of a measurement site used in previous experimental work in central London. The detector was set at the location of the rooftop site as the tracer was released at a range of locations within the surrounding streets and rooftops. Concentration measurements are presented for a range of wind angles, with the spread of concentration measurements indicative of the source area distribution. Clear evidence of wind channeling by streets is seen with the shape of the source area strongly influenced by buildings upwind of the measurement point. The results of the wind tunnel study are compared to scalar concentration source areas generated by modelling approaches based on meteorological data from the central London experimental site and used in the interpretation of continuous carbon dioxide (CO2) concentration data. Initial conclusions will be drawn as to how to apply scalar concentration source area models to rooftop measurement sites and

  19. Novel medicines marketed in the UK (1960-87).

    PubMed Central

    Lis, Y; Walker, S R

    1989-01-01

    1. A total of six hundred and eighty three new chemical entities (NCEs), were marketed in the UK between 1960 and 1987. The number of NCEs introduced annually onto the UK market declined to an average of 20 per year in 1964 and subsequently to only 7 in 1985. 2. Average development times have increased fourfold since 1960 to a peak value of 13 years in 1984. The concomitant decline in effective patent life has resulted in a mean effective patent life of less than 10 years since the mid 1960s and no more than 6 years since the early 1980s, except for the cohort marketed in 1987. 3. The largest contribution to total development time was made by the clinical phase. For NCEs marketed in the mid 1960s it was 3.3 years increasing to a peak of almost 8 years in the early 1980s, and representing on average two-thirds of research and development time. 4. Between 1960 and the early 1970s total development time for central nervous system (CNS) agents, cardiovascular products and anti-infectives had doubled to 9, 8 and 7.3 years respectively. By the 1980s it was averaging 13 years for CNS agents and was 54% and 28% longer than for anti-infectives and cardiovascular compounds respectively. PMID:2789928

  20. Are medical educators in general practice untapped potential to increase training capacity in sexual and reproductive healthcare? Results of a survey in London, UK

    PubMed Central

    Ma, Richard; Shah, Radhika

    2016-01-01

    Abstract Background Long waiting times for training in sexual and reproductive healthcare (SRH) including long acting reversible contraception (LARC) might lead to attrition from training programmes, leading to reduced capacity for sexual health services, and reduced access to such contraception for women. Setting General practice in London, UK. Question Can medical educators in general practice be used as untapped potential to train other health care professionals in sexual and reproductive healthcare? Method We conducted an online survey to find out the qualifications, skills and willingness of established educators in primary care in London to train other clinicians in sexual and reproductive healthcare, including LARC. Results We received 124 responses from medical educators (10.1% response rate from general practitioner (GP) trainers and 59.0% of clinical supervisors for Foundation Year doctors). 86 (69.9%) had diploma of the Faculty of Sexual and Reproductive Healthcare (DFSRH) qualification and further 18 (14.6%) were interested in obtaining this qualification. Eleven respondents were trained to fit intrauterine contraception only, three for contraceptive implants only and 37 were trained to fit both. 50 (40.3%) of 124 respondents were willing get involved in DFSRH training; 74% of these were willing to teach on any component of DFSRH including LARC. Discussion There is a shortage of training places and long waiting list for clinicians who wish to train in SRH. This survey suggests there is a pool of GP educators with skills and experience in SRH and are willing to train others. This can potentially increase the training capacity and improve overall access to good contraception and LARC for women. PMID:28250840

  1. Applying quality improvement methods to address gaps in medicines reconciliation at transfers of care from an acute UK hospital

    PubMed Central

    Marvin, Vanessa; Kuo, Shirley; Vaughan, Louella

    2016-01-01

    Objectives Reliable reconciliation of medicines at admission and discharge from hospital is key to reducing unintentional prescribing discrepancies at transitions of healthcare. We introduced a team approach to the reconciliation process at an acute hospital with the aim of improving the provision of information and documentation of reliable medication lists to enable clear, timely communications on discharge. Setting An acute 400-bedded teaching hospital in London, UK. Participants The effects of change were measured in a simple random sample of 10 adult patients a week on the acute admissions unit over 18 months. Interventions Quality improvement methods were used throughout. Interventions included education and training of staff involved at ward level and in the pharmacy department, introduction of medication documentation templates for electronic prescribing and for communicating information on medicines in discharge summaries co-designed with patient representatives. Results Statistical process control analysis showed reliable documentation (complete, verified and intentional changes clarified) of current medication on 49.2% of patients' discharge summaries. This appears to have improved (to 85.2%) according to a poststudy audit the year after the project end. Pharmacist involvement in discharge reconciliation increased significantly, and improvements in the numbers of medicines prescribed in error, or omitted from the discharge prescription, are demonstrated. Variation in weekly measures is seen throughout but particularly at periods of changeover of new doctors and introduction of new systems. Conclusions New processes led to a sustained increase in reconciled medications and, thereby, an improvement in the number of patients discharged from hospital with unintentional discrepancies (errors or omissions) on their discharge prescription. The initiatives were pharmacist-led but involved close working and shared understanding about roles and responsibilities

  2. Quality of Life and Unmet Need in People with Psychosis in the London Borough of Haringey, UK

    PubMed Central

    Lambri, Maria; Chakraborty, Apu; Leavey, Gerard; King, Michael

    2012-01-01

    Objectives. Deinstitutionalization of long-term psychiatric patients produced various community-based residential care facilities. However, inner-city areas have many patients with severe mental illness (SMI) as well as deprivation, unemployment, and crime. This makes meeting their community needs complex. We undertook a needs assessment of service provision and consonance between service users' evaluation of need and by care workers. Design. Cross-sectional study with random sample of SMI service users in four housing settings: rehabilitation units; high-supported; medium-supported; low-supported housing. Setting. London Borough of Haringey. Outcome Measures. 110 SMI service users and 110 keyworkers were interviewed, using Camberwell Assessment of Need; SF-36; Lancashire Quality-of-Life profile; demographic and clinical information. Results. People in “low-support” and “high-support” housing had similar symptom scores, though low support had significantly lower quality of life. Quality of life was positively predicted by self-reported mental-health score and negatively predicted by unmet-need score in whole sample and in medium-support residents. Residents' and care-workers' assessments of need differed considerably. Conclusions. Although patients' housing needs were broadly met, those in low-supported housing fared least well. Attendance to self-reported mental health and unmet social needs to quality of life underpins planning of residential services for those with SMI. Social and personal needs of people in supported housing may be underestimated and overlooked; service providers need to prioritise these if concept of “recovery” is to advance. PMID:23213300

  3. The introduction of 10% renewable energy in every building. Possibility or probability? Case study: Granville plus community Centre London, UK

    NASA Astrophysics Data System (ADS)

    Tsitnidis, Petros

    This thesis investigates the ways of producing 10% of the energy consumed in a site from renewable energy sources. It analyses how this can be accomplished by considering the general frame of the subject and referring to the general problem of climate change and its effects on the planet. Special attention is paid to architecture and an attempt is made to answer the question how the built environment can cope with this problem. Reference is also made to the UK's latest guidelines on the issue. The introduction of the 10% renewable energy use in buildings, known as the "Merton Rule", is one of the most pioneering guidelines towards sustainability. The thesis is continued with the post-occupancy assessment on a four year-old building, part of a much older community center complex that has been built with very advanced design and strict environmental targets but suffers from lack of care and management. The building does not achieve optimum performance as there are difficulties with various stakeholders in the buildings management. This thesis, therefore, examines possible solutions and suggests ways of improvement. The study concludes with remarks and suggestions based on simulation and assessment procedures. New ventilation strategies are proposed to be introduced to the building together with a series of ways to reduce the highest internal temperatures of the first floor. Extensive reference is also made to the initial sustainable approach of the design. The interventions proposed have as a target the improvement of the energy performance and the minimization of the carbon footprint of the building. Keywords: environmental design, sustainable architecture, granville plus, Merton Rule.

  4. Energy exchanges in a Central Business District - Interpretation of Eddy Covariance and radiation flux measurements (London UK)

    NASA Astrophysics Data System (ADS)

    Kotthaus, S.; Grimmond, S.

    2013-12-01

    Global urbanisation brings increasingly dense and complex urban structures. To manage cities sustainably and smartly, currently and into the future under changing climates, urban climate research needs to advance in areas such as Central Business Districts (CBD) where human interactions with the environment are particularly concentrated. Measurement and modelling approaches may be pushed to their limits in dense urban settings, but if urban climate research is to contribute to the challenges of real cities those limits have to be addressed. The climate of cities is strongly governed by surface-atmosphere exchanges of energy, moisture and momentum. Observations of the relevant fluxes provide important information for improvement and evaluation of modelling approaches. Due to the CBD's heterogeneity, a very careful analysis of observations is required to understand the relevant processes. Current approaches used to interpret observations and set them in a wider context may need to be adapted for use in these more complex areas. Here, we present long-term observations of the radiation balance components and turbulent fluxes of latent heat, sensible heat and momentum in the city centre of London. This is one of the first measurement studies in a CBD covering multiple years with analysis at temporal scales from days to seasons. Data gathered at two sites in close vicinity, but with different measurement heights, are analysed to investigate the influence of source area characteristics on long-term radiation and turbulent fluxes. Challenges of source area modelling and the critical aspect of siting in such a complex environment are considered. Outgoing long- and short-wave radiation are impacted by the anisotropic nature of the urban surface and the high reflectance materials increasingly being used as building materials. Results highlight the need to consider the source area of radiometers in terms of diffuse and direct irradiance. Sensible heat fluxes (QH) are positive

  5. Delivery and collection of radioactive packages to and from UK hospital nuclear medicine departments.

    PubMed

    Lawson, Richard S; Davies, Glyn; Hesslewood, Stuart R; Hinton, Paul J; Maxwell, Alan

    2004-12-01

    Under radiation protection legislation in the UK, employers have a duty to maintain appropriate records to account for radioactive materials in their possession and to ensure security of these materials. This applies to radioactive packages, containing items such as technetium generators, which are regularly delivered to hospital nuclear medicine departments. It also applies to the collection of packages, such as those containing used generators for return to the supplier. This article has been written by the professional bodies representing nuclear medicine in the UK in order to provide guidance to hospitals on appropriate procedures that will comply with the legislation. General principles, which should be met by any acceptable protocol, are stated, and practical guidance on how these may be implemented is given. Some example scenarios are outlined.

  6. European Pharmaceutical Pricing and Reimbursement--SMi's 21st Annual Meeting (October 5-6, 2015--London, UK).

    PubMed

    Kibble, A; D'Souza, P

    2015-10-01

    Translating perceived market value for pharmaceutical products into a willingness to pay remains the key factor in ensuring market access and return on investment. How price is managed in the context of new market entrants or new approval settings can create complex challenges, and further complexity is added through diverse global reimbursement structures and the myriad of stakeholders involved at every step of value identification. SMi's 21st Annual Meeting on European Pricing and Reimbursement presented a program focused on the measures being taken by European healthcare systems as they seek to facilitate access to the latest treatments while delivering value for payers and patients. Supporting patient access to life-changing medicines is a challenge, and funders are responding in many different ways; however, while the pharma industry continues to focus its efforts on high cost drugs that treat diseases of the few, the disconnect will be not be resolved. The speakers and delegates at the annual meeting believe success is possible by focusing on value for patients, driven by provider experience, scale and learning. Instead of simply lowering costs, companies, providers and payers can more adequately contribute to the goals of funders as well as the treatment needs of patients.

  7. Associations of short-term exposure to traffic-related air pollution with cardiovascular and respiratory hospital admissions in London, UK

    PubMed Central

    Samoli, Evangelia; Atkinson, Richard W; Analitis, Antonis; Fuller, Gary W; Green, David C; Mudway, Ian; Anderson, H Ross; Kelly, Frank J

    2016-01-01

    Objectives There is evidence of adverse associations between short-term exposure to traffic-related pollution and health, but little is known about the relative contribution of the various sources and particulate constituents. Methods For each day for 2011–2012 in London, UK over 100 air pollutant metrics were assembled using monitors, modelling and chemical analyses. We selected a priori metrics indicative of traffic sources: general traffic, petrol exhaust, diesel exhaust and non-exhaust (mineral dust, brake and tyre wear). Using Poisson regression models, controlling for time-varying confounders, we derived effect estimates for cardiovascular and respiratory hospital admissions at prespecified lags and evaluated the sensitivity of estimates to multipollutant modelling and effect modification by season. Results For single day exposure, we found consistent associations between adult (15–64 years) cardiovascular and paediatric (0–14 years) respiratory admissions with elemental and black carbon (EC/BC), ranging from 0.56% to 1.65% increase per IQR change, and to a lesser degree with carbon monoxide (CO) and aluminium (Al). The average of past 7 days EC/BC exposure was associated with elderly (65+ years) cardiovascular admissions. Indicated associations were higher during the warm period of the year. Although effect estimates were sensitive to the adjustment for other pollutants they remained consistent in direction, indicating independence of associations from different sources, especially between diesel and petrol engines, as well as mineral dust. Conclusions Our results suggest that exhaust related pollutants are associated with increased numbers of adult cardiovascular and paediatric respiratory hospitalisations. More extensive monitoring in urban centres is required to further elucidate the associations. PMID:26884048

  8. Personal exposure of street canyon intersection users to PM 2.5, ultrafine particle counts and carbon monoxide in Central London, UK

    NASA Astrophysics Data System (ADS)

    Kaur, S.; Nieuwenhuijsen, M.; Colvile, R.

    Short-term human exposure to PM 2.5, ultrafine particle counts (particle range: 0.02-1 μm) and carbon monoxide (CO) was investigated at and around a street canyon intersection in Central London, UK. During a four-week field campaign, groups of four volunteers collected samples at three timings (morning, lunch and afternoon), along two different routes (a heavily trafficked route and a backstreet route) via five modes of transport (walking, cycling, bus, car and taxi). PM 2.5 was sampled using high-flow gravimetric personal samplers, ultrafine particle counts were measured using TSI P-TRAKs and Langans were used to measure CO exposure. Three hundred and ninety-four samples were collected—197 PM 2.5, 86 ultrafine particle count and 111 CO. Arithmetic means of PM 2.5 personal exposure were 27.5, 33.5, 34.5, 38.0 and 41.5 μg m -3, ultrafine particle counts were 67 773, 93 968, 101 364, 99 736 and 87 545 pt cm -3 and CO levels were 0.9, 1.1, 0.8, 1.3 and 1.1 ppm for walking, cycling, bus, car and taxi respectively. On the heavily trafficked route, personal exposure was 35.3 μg m -3, 101142 pt cm -3 and 1.3 ppm, and on the backstreet route it was 31.8 μg m -3, 71628 pt cm -3 and 0.6 ppm for PM 2.5, ultrafine particle counts and CO, respectively. Personal exposure levels were high during the morning measurements for all three pollutants (34.6 μg m -3, 106 270 pt cm -3 and 1.5 ppm for PM 2.5, ultrafine particle counts and CO, respectively).There was a moderately strong correlation between personal exposure of ultrafine particle counts and CO ( r=0.7, N=67) but a weaker correlation between PM 2.5 and ultrafine particle counts ( r=0.5, N=83) and a low correlation between PM 2.5 and CO exposure ( r=0.2, N=105). The exposure assessment also revealed that the background and kerbside monitoring stations were not representative of the personal exposure of individuals to PM 2.5 and CO at and around a street canyon intersection.

  9. Training in clinical forensic medicine in the UK--perceptions of current regulatory standards.

    PubMed

    Stark, Margaret M; Norfolk, Guy A

    2011-08-01

    As clinical forensic medicine (CFM) is not currently recognised as a speciality in the UK there are no nationally agreed mandatory standards for training forensic physicians in either general forensic (GFM) or sexual offence medicine (SOM). The General Medical Council (GMC), the medical regulator in the UK, has issued clear standards for training in all specialities recommending that "trainees must be supported to acquire the necessary skills and experience through induction, effective educational supervision, an appropriate workload and time to learn". In order to evaluate the current situation in the field of clinical forensic medicine, doctors who have recently (within the last two years) started working in the field "trainees" (n = 38), and trainers (n = 61) with responsibility for clinical and educational supervision of new trainees, were surveyed by questionnaire to gather their perceptions of how the relevant GMC standards are being met in initial on-the-job training. Telephone interviews were performed with eleven doctors working as clinical or medical directors to determine their views. It is clear that currently the quality of training in CFM is sub-standard and inconsistent and that the published standards, as to the minimum requirement for training that must be met by post-graduate medical and training providers at all levels, are not being met. The Faculty of Forensic and Legal Medicine (FFLM) needs to set explicit minimum standards which will comply with the regulator and work to pilot credentialing for forensic physicians. A number of recommendations are made for urgent FFLM development.

  10. Global update: UK.

    PubMed

    Culme-Seymour, Emily J

    2012-11-01

    2012 has been an exciting year in the UK with substantial development on every front - research, clinical, industry and government. In particular, the focus has now moved to encompass far more post-research activities, with the continued enrolment of patients onto two pioneering Phase I clinical trials: ReNeuron's ReN001 stem cell therapy for stroke (PISCES) in Southern General Hospital, Greater Glasgow and Advanced Cell Technology's retinal pigment epithelial cells derived from human embryonic stem cells for Stargardts macular dystrophy and dry age-related macular degeneration at Moorfields Eye Hospital, London. The funding landscape for the sector has evolved from previous years to more fully embrace development and translation, including the provision of £180 million available for biomedical research via the Biomedical Catalyst Fund (joint Technology Strategy Board and Medical Research Council [MRC] funding) and a further £25 million through the UK Research Council's UK Regenerative Medicine Platform initiative, as well as ongoing developments with the Cell Therapy Catapult, which all act to further encourage a pan-UK collaborative environment. Overall, the UK cell therapy community continues to thrive and impact heavily upon the worldwide sector, with an established research base, a solid approach to translation and a small but growing commercial sector that is going from strength to strength.

  11. Racial origin, sexual lifestyle, and genital infection among women attending a genitourinary medicine clinic in London (1992)

    PubMed Central

    Evans, B. A.; Kell, P. D.; Bond, R. A.; MacRae, K. D.

    1998-01-01

    OBJECTIVES: To compare variables of sexual behaviour and incidence of genital infections among women of different racial origins and lifestyles. DESIGN: A prospective cross sectional study of sexual behaviour reported by a standardised self administered questionnaire in new patients who presented for screening and diagnosis. SETTING: A genitourinary medicine clinic in west London. SUBJECTS: 1084 consecutive women newly attending in 1992. MAIN OUTCOME MEASURES: Variables relating to sociodemographic status, sexual lifestyle, condom use, sexually transmitted diseases, and other genital infections stratified by racial origin. RESULTS: There were 948 evaluable women, of whom 932 (98.3%) were heterosexual and 16 (1.7%) were lesbian. Previous heterosexual intercourse was reported by 69% of lesbian women and their most frequent diagnosis was bacterial vaginosis (38%). The majority of heterosexual women were white (78%) and 16% were black. The black women were more likely to be teenagers (18% cf 8%; p = 0.0004) or students (28% cf 15%; p = 0.0008), and to have had an earlier coitarche (48% cf 38% before aged 17; p < 0.004). They also had a higher proportion of pregnancies (58% cf 38%; p < 0.00001) and births (38% cf 20%; p < 0.00001). The white women showed significantly more sexual partners during the preceding year (p = 0.004) and in total (p < 0.00001) and more reported non-regular partners (48% cf 35%; p = 0.004) with whom they were more likely to use condoms (p = 0.009). However, the black women were more likely to have gonorrhoea (7% cf 2% p < 0.0003), chlamydial infection (12% cf 5% p < 0.002), trichomoniasis (10% cf 2% p < 0.00001), or to sexual contacts of men with non-gonococcal urethritis (19% cf 12% p < 0.02). They were less likely to have genital warts (3% cf 12% p = 0.002). Logistic regression showed that all these variables were independently associated with the black women. The Asian women (2%), none of whom had a sexually transmitted disease, had commenced

  12. Factors associated with travel to non-local genitourinary medicine clinics for gonorrhoea: an analysis of patients diagnosed in London, 2009-10.

    PubMed

    Le Polain de Waroux, Olivier; Hughes, Gwenda; Maguire, Helen; Crook, Paul D

    2014-03-01

    We analysed factors associated with travelling to non-local genitourinary medicine clinics for gonorrhoea care in London. We used surveillance data on London residents attending genitourinary medicine clinics in 2009-10 and calculated distances between patients' areas of residence and both the nearest genitourinary medicine clinic and the clinic attended. Non-local clinics were attended by 5408 (46.7%) patients. Men having sex with men attended non-local services more than heterosexuals (OR 3.83, p < 0.001). Among heterosexual men, black Africans and black Caribbeans were more likely, and South Asians less likely, to attend non-local services compared to whites (OR [95%CI] 1.33 [1.04-1.72], 1.36 [1.11-1.67] and 0.46 [0.31-0.70] respectively). Similar associations, although not statistically significant, were found in women. People were more likely to attend local services if their local clinic provided walk-in and young people's services, weekend consultations and long opening hours. These findings could help design services meeting local population needs and facilitate prompt and equitable access to care.

  13. UK: the current state of regulation of complementary and alternative medicine.

    PubMed

    Walker, L A; Budd, S

    2002-03-01

    There is no legislation that restricts the practice of CAM in the UK apart from the practice of chiropractic and osteopathy and limits on advertising the treatments of certain conditions such as cancer and tuberculosis. The UK government has increasingly recognised the need for comprehensive regulation of CAM, though it abandoned its original plan for a single overarching regulatory body. Initiatives to examine and hasten the process of regulation have included setting up a central, well-recognised charitable body to facilitate progress for individual professions, and an authoritative survey of the existing professional organisations. One pathway open to individual professions is statutory self-regulation, which requires a single governing body, a systematic corpus of knowledge, recognised training courses and demonstrated efficacy. The other pathway is voluntary self-regulation. Chiropractic and osteopathy have adopted statutory self-regulation, though this has proved expensive for individual members of these professions. A recent House of Lords report on CAM has recommended that the herbal medicine and acupuncture professions should also develop a system of statutory regulation. Other professions, such as aromatherapy, are in the process of establishing single professional bodies as a first step towards self-regulation. Among the issues that remain to be resolved is the relationship between the CAM professions and statutory registered practitioners who also practise CAM.

  14. Nutrition Labeling and Portion Size Information on Children's Menus in Fast-Food and Table-Service Chain Restaurants in London, UK

    ERIC Educational Resources Information Center

    Reeves, Sue; Wake, Yvonne; Zick, Andrea

    2011-01-01

    Objective: To investigate meals, price, nutritional content, and nutrition and portion size information available on children's menus in fast-food and table-service chain restaurants in London, since the United Kingdom does not currently require such information but may be initiating a voluntary guideline. Methods: Children's menus were assessed…

  15. Airborne determination of the temporo-spatial distribution of benzene, toluene, nitrogen oxides and ozone in the boundary layer across Greater London, UK

    NASA Astrophysics Data System (ADS)

    Shaw, M. D.; Lee, J. D.; Davison, B.; Vaughan, A.; Purvis, R. M.; Lewis, A. C.; Hewitt, C. N.

    2014-10-01

    Highly spatially resolved mixing ratios of benzene and toluene, nitrogen oxides (NOx) and ozone (O3) were measured in the atmospheric boundary layer above Greater London during the period 24 June to 9 July 2013 using a Dornier 228 aircraft. Toluene and benzene were determined in-situ using a proton transfer reaction mass spectrometer (PTR-MS), NOx by dual channel NOx chemiluminescence and O3 mixing ratios by UV absorption. Average mixing ratios observed over inner London at 360 ± 10 m a.g.l. were 0.20 ± 0.05, 0.28 ± 0.07, 13.2 ± 8.6, 21.0 ± 7.3 and 34.3 ± 15.2 ppbv for benzene, toluene, NO, NO2 and NOx respectively. Linear regression analysis between NO2, benzene and toluene mixing ratios yielded a trimodal distribution indicating that these compounds predominantly share the same or co-located sources within the city and that a significant fraction of NOx is directly emitted as NO2. Average mixing ratios measured at 360 ± 10 m a.g.l. over outer London were always lower than over inner London. Where traffic densities were highest, the toluene / benzene (T / B) concentration ratios were highest (average of 1.8 ± 0.3 ppbv ppbv-1) indicative of strong local sources. Daytime maxima in NOx, benzene and toluene mixing ratios were observed in the morning (~40 ppbv NOx, ~350 pptv toluene and ~200 pptv benzene) and for ozone in the mid-afternoon (~40 ppbv O3) all at 360 ± 10 m a.g.l.

  16. Airborne determination of the temporo-spatial distribution of benzene, toluene, nitrogen oxides and ozone in the boundary layer across Greater London, UK

    NASA Astrophysics Data System (ADS)

    Shaw, M. D.; Lee, J. D.; Davison, B.; Vaughan, A.; Purvis, R. M.; Harvey, A.; Lewis, A. C.; Hewitt, C. N.

    2015-05-01

    Highly spatially resolved mixing ratios of benzene and toluene, nitrogen oxides (NOx) and ozone (O3) were measured in the atmospheric boundary layer above Greater London during the period 24 June to 9 July 2013 using a Dornier 228 aircraft. Toluene and benzene were determined in situ using a proton transfer reaction mass spectrometer (PTR-MS), NOx by dual-channel NOx chemiluminescence and O3 mixing ratios by UV absorption. Average mixing ratios observed over inner London at 360 ± 10 m a.g.l. were 0.20 ± 0.05, 0.28 ± 0.07, 13.2 ± 8.6, 21.0 ± 7.3 and 34.3 ± 15.2 ppbv for benzene, toluene, NO, NO2 and NOx respectively. Linear regression analysis between NO2, benzene and toluene mixing ratios yields a strong covariance, indicating that these compounds predominantly share the same or co-located sources within the city. Average mixing ratios measured at 360 ± 10 m a.g.l. over outer London were always lower than over inner London. Where traffic densities were highest, the toluene / benzene (T / B) concentration ratios were highest (average of 1.8 ± 0.5 ppbv ppbv-1), indicative of strong local sources. Daytime maxima in NOx, benzene and toluene mixing ratios were observed in the morning (~ 40 ppbv NOx, ~ 350 pptv toluene and ~ 200 pptv benzene) and in the mid-afternoon for ozone (~ 40 ppbv O3), all at 360 ± 10 m a.g.l.

  17. Partnerships in Pharma--An Economist Intelligence Unit Seminar--Building Innovation into Alliances and Business Models. 1 October 2010, London, UK.

    PubMed

    Kibble, Alexandra

    2010-12-01

    The Partnerships in Pharma seminar, held in London, included topics related to building innovation into alliances and business models within the pharmaceutical industry. This conference report highlights selected presentations on strategies for successful partnering, partnering alongside an evolving CRO industry, considering the pharma value chain, and partnerships between industry and academia. Approaches used by Ipsen, Merck Serono, Pfizer and ViiV Healthcare are also described.

  18. The 8th International Conference on Counter-current Chromatography held at Brunel University, London, UK, July 23-25, 2014.

    PubMed

    Ignatova, Svetlana; Sutherland, Ian

    2015-12-18

    The 8th International Conference on Counter-current Chromatography (CCC2014) was held at Brunel University London from July 23rd to 25th, 2014. It has been 14 years since Brunel hosted the first International Conference on CCC (CCC2000) at the beginning of the millennium and therefore, it was a good opportunity to review the progress of this emerging technology and particularly the impact it is having with industry today.

  19. Assessment of the impact of the London Olympics 2012 on selected non-genitourinary medicine clinic sexual health services.

    PubMed

    Hartley, A; Foster, R; Brook, M G; Cassell, J A; Mercer, C H; Coyne, K; Hughes, G; Crook, P

    2015-04-01

    With minimal information on sexual health provision during mass-gathering events, our aim was to describe the use of sexual health, contraceptive, sex worker and sexual assault services during the London 2012 Olympics. We analysed data from five sources. One contraceptive service provider reported a 10% increase in attendance during the main Games, while emergency contraception prescriptions rose during the main Olympics, compared to the week before, but were similar or lower than at the beginning and end of the summer period. A health telephone advice line reported a 16% fall in sexual health-related calls during the main Olympics, but a 33% increase subsequently. London sexual assault referral centres reported that 1.8% of sexual assaults were Olympics-linked. A service for sex workers reported that 16% started working in the sex industry and 7% moved to London to work during the Olympics. Fifty-eight per cent and 45% of sex workers reported fewer clients and an increase in police crack-downs, respectively. Our results show a change in activity across these services during the 2012 summer, which may be associated with the Olympics. Our data are a guide to other services when anticipating changes in service activity and planning staffing for mass-gathering events.

  20. Women in senior post-graduate medicine career roles in the UK: a qualitative study

    PubMed Central

    Curtis, Anthony; Eley, Lizzie; Irish, Bill

    2016-01-01

    Objectives This qualitative study sought to elicit the views, experiences, career journeys and aspirations of women in senior post-graduate medical education roles to identify steps needed to help support career progression. Design In-depth semi-structured telephone interviews. Setting UK. Participants Purposive sample of 12 women in a variety of senior leadership roles in post-graduate medical education in the UK. Main outcome measures Self reported motivating influences, factors that helped and hindered progress, key branch points, and key educational factors and social support impacting on participants' career in postgraduate medicine. Results Respondents often reported that career journeys were serendipitous, rather than planned, formal or well structured. Senior women leaders reported having a high internal locus of control, with very high levels of commitment to the NHS. All reported significant levels of drive, although the majority indicated that they were not ambitious in the sense of a strong drive for money, prestige, recognition or power. They perceived that there was an under-representation of women in senior leadership positions and that high-quality female mentorship was particularly important in redressing this imbalance. Social support, such a spouse or other significant family member, was particularly valued as reaffirming and supporting women’s chosen career ambition. Factors that were considered to have hindered career progression included low self-confidence and self-efficacy, the so-called glass ceiling and perceived self-limiting cultural influences. Factors indirectly linked to gender such as part-time versus working full time were reportedly influential in being overlooked for senior leadership roles. Implications of these findings are discussed in the paper. Conclusion Social support, mentorship and role modelling are all perceived as highly important in redressing perceived gender imbalances in careers in post-graduate medical education

  1. Dental age assessment (DAA) of Afro-Trinidadian children and adolescents. Development of a Reference Dataset (RDS) and comparison with Caucasians resident in London, UK.

    PubMed

    Moze, Kevin; Roberts, Graham

    2012-07-01

    The large number of extant Dental Panoramic Tomographs of Afro-Trinidadian subjects were collected and Tooth Development Stages (TDSs) were assessed for each of the 878 radiographs to provide a Reference Dataset (RDS) of Afro-Trinidadian children and adolescents. The values for each of the 256 TDSs present were statistically significantly different from the values for the same TDSs in the UK Caucasian RDS. A validation study of 50 radiographs of Afro-Trinidadian subjects from 24 boys and 26 girls were assessed to enable calculation of the Dental Age (DA). The DA calculated using the UK Caucasian RDS was statistically significantly different from the chronological age. The same radiographs were used to calculate the Age of Attainment of the individual Tooth Development Stages for females and males in both the UK Caucasian subjects, and the Afro-Trinidadians. The majority of these comparisons showed the TDSs in Afro-Trinidadian subjects to develop earlier than the UK Caucasian subjects by approximately 8 months.

  2. Fritz London

    NASA Astrophysics Data System (ADS)

    Gavroglu, Kostas

    2005-11-01

    Preface; Acknowledgements; Part I. From Philosophy to Physics: The years that left nothing unaffected; 1. The appeal of ideas; 2. Goëthe as a scientist; 3. How absolute is our knowledge?; 4. How do we come to know things?; 5. London's teachers in philosophy; 6. Husserl's teachings; 7. Expectations of things to come; 8. The thesis in philosophy; 9. Tolman's principle of similitude; 10. The necessary clarifications; 11. Work on quantum theory; 12. Transformation theory; 13. Unsuccessful attempts at unification; Part II. The Years in Berlin and the Beginnings of Quantum Chemistry: The mysterious bond; 14. London in Zürich; 15. Binding forces; 16. The Pauli principle; 17. Reactions to the Heitler-London paper; 18. Polyelectronic molecules and the application of group theory to problems of chemical valence; 19. Chemists as physicists?; 20. London's first contacts in Berlin; 21. Marriage; 22. Job offers; 23. Intermolecular forces; 24. The book which could not be written; 25. Leningrad and Rome; 26. Difficulties with group theory; 27. Linus Pauling's resonance structures; 28. Robert Mulliken's molecular orbitals; Part III. Oxford and Superconductivity: The rise of the Nazis; 29. Going to Oxford; 30. Lindemann, Simon and Heinz London; 31. Electricity in the very cold; 32. The end of old certainties; 33. The thermodynamic treatment; 34. The theory of Fritz and Heinz London; 35. Initial reactions by von Laue; 36. The discussion at the Royal Society; 37. Termination of the ICI fellowship; Part IV. Paris and Superfluidity: The Front Populaire; 38. The article in Nature 1937 and 'Nouvelle Conception'; 39. Laue again; 40. The structure of solid helium; 41. The peculiar properties of helium; 42. Bose-Einstein condensation; 43. The note in Nature; 44. The two-fluid model; 45. The trip to Jerusalem; 46. Leaving again; 47. The observer in quantum mechanics; Part V. United States and the Typing up of Loose Ends: Duke University, North Carolina; 48. The Soviet Union, Kapitza and

  3. National audit of asymptomatic screening in UK genitourinary medicine clinics: case-notes audit.

    PubMed

    McClean, H; Carne, C A; Sullivan, A K; Menon-Johansson, A; Gokhale, R; Sethi, G; Mammen-Tobin, A G; Daniels, D

    2010-07-01

    A national audit of screening of asymptomatic patients seen in UK genitourinary medicine clinics in 2009 was conducted against the national guidelines. Data were aggregated by regions and clinics in regions, allowing practice to be compared within and between regions, as well as to national averages and against national guidelines. The case-notes of 4428 patients were audited. Performance was over 80% against the national guidelines for screening of asymptomatic heterosexual men, men who have sex with men (MSM) and women for chlamydial, gonorrhoeal, syphilis and HIV infections. However, the recommended method of endocervical culture for gonorrhoea was performed in only 65% of women, with a further one-quarter being screened with endocervical or vulvovaginal nucleic acid amplification tests (NAATs). Although significant NAAT use for gonorrhoea was seen in all groups, testing for gonorrhoea by culture is still recommended as a first-line test on invasive samples. Over 80% of MSM, who were not known to be immune, were screened for hepatitis B. Urethral microscopy was performed in 22% of heterosexual men and 17% of MSM, and cervical microscopy in 12% of women.

  4. Analysis of the potential of near ground measurements of CO2 and CH4 in London, UK for the monitoring of city-scale emissions using an atmospheric transport model

    NASA Astrophysics Data System (ADS)

    Boon, A.; Broquet, G.; Clifford, D. J.; Chevallier, F.; Butterfield, D. M.; Pison, I.; Ramonet, M.; Paris, J. D.; Ciais, P.

    2015-11-01

    Carbon dioxide (CO2) and methane (CH4) mole fractions were measured at four near ground sites located in and around London during the summer of 2012 in view to investigate the potential of assimilating such measurements in an atmospheric inversion system for the monitoring of the CO2 and CH4 emissions in the London area. These data were analysed and compared with simulations using a modelling framework suited to building an inversion system: a 2 km horizontal resolution South of England configuration of the transport model CHIMERE driven by European Centre for Medium-Range Weather Forecasting (ECMWF) meteorological forcing, coupled to a 1 km horizontal resolution emission inventory (the UK National Atmospheric Emission Inventory). First comparisons reveal that local sources have a large impact on measurements and these local sources cannot be represented in the model at 2 km resolution. We evaluate methods to minimise some of the other critical sources of misfits between the observation data and the model simulation that overlap the signature of the errors in the emission inventory. These methods should make it easier to identify the corrections that should be applied to the inventory. Analysis is supported by observations from meteorological sites around the city and a three-week period of atmospheric mixing layer height estimations from lidar measurements. The difficulties of modelling the mixing layer depth and thus CO2 and CH4 concentrations during the night, morning and late afternoon led us to focus on the afternoon period for all further analyses. The misfits between observations and model simulations are high for both CO2 and CH4 (i.e., their root mean square (RMS) is between 8 and 12 parts per million (ppm) for CO2 and between 30 and 55 parts per billion (ppb) for CH4 at a given site). By analysing the gradients between the urban sites and a suburban or rural reference site, we are able to decrease the impact of uncertainties in the fluxes and transport

  5. Experiential Approaches to the Global City: London as Social Laboratory

    ERIC Educational Resources Information Center

    Gristwood, Anthony; Woolf, Michael

    2011-01-01

    London is the paramount example of a city that is not bounded by its geography and cannot be grasped in isolation. The U.K.'s national capital and the prime focus for business, finance and creative industries, London also transcends the U.K.'s borders as a hub of the world economy. This paper argues that London, a city riddled by the socioeconomic…

  6. A review of the cultivation and processing of cannabis (Cannabis sativa L.) for production of prescription medicines in the UK.

    PubMed

    Potter, David J

    2014-01-01

    The quality demands of the pharmaceutical industry require prescription medicines to be consistent in their active ingredient content. Achieving this, using raw cannabis as a feedstock, is especially challenging. The plant material is extremely inhomogeneous, and the ratios of active ingredients are affected by a range of factors. These include the genetics of the plant, the growing and storage conditions, the state of maturity at harvest, and the methods used to process and formulate the material. The reasons for this variability are described, with particular emphasis on the botanical considerations. To produce the complex botanical medicine Sativex®, which contains the cannabinoids Δ(9)-tetrahydrocannabinol (THC) and cannabidiol (CBD) and a range of other ingredients, GW Pharmaceuticals had to manage these variables. This medicine, for the treatment of spasticity due to multiple sclerosis, is the first cannabis-based medicine to be approved in the UK. The company's methodology for producing this and other chemotypes is described.

  7. A time-series analysis of any short-term effects of meteorological and air pollution factors on preterm births in London, UK.

    PubMed

    Lee, Sue J; Hajat, Shakoor; Steer, Philip J; Filippi, Veronique

    2008-02-01

    Although much is known about the incidence and burden of preterm birth, its biological mechanisms are not well understood. While several studies have suggested that high levels of air pollution or exposure to particular climatic factors may be associated with an increased risk of preterm birth, other studies do not support such an association. To determine whether exposure to various environmental factors place a large London-based population at higher risk for preterm birth, we analyzed 482,568 births that occurred between 1988 and 2000 from the St. Mary's Maternity Information System database. Using an ecological study design, any short-term associations between preterm birth and various environmental factors were investigated using time-series regression techniques. Environmental exposures included air pollution (ambient ozone and PM(10)) and climatic factors (temperature, rainfall, sunshine, relative humidity, barometric pressure, and largest drop in barometric pressure). In addition to exposure on the day of birth, cumulative exposure up to 1 week before birth was investigated. The risk of preterm birth did not increase with exposure to the levels of ambient air pollution or meteorological factors experienced by this population. Cumulative exposure from 0 to 6 days before birth also did not show any significant effect on the risk of preterm birth. This large study, covering 13 years, suggests that there is no association between preterm births and recent exposure to ambient air pollution or recent changes in the weather.

  8. Animal models and antibody assays for evaluating candidate SARS vaccines: summary of a technical meeting 25-26 August 2005, London, UK.

    PubMed

    Roberts, Anjeanette; Wood, John; Subbarao, Kanta; Ferguson, Morag; Wood, David; Cherian, Thomas

    2006-11-30

    Severe acute respiratory syndrome (SARS) emerged in the Guangdong province of China in late 2002 and spread to 29 countries. By the end of the outbreak in July 2003, the CDC and WHO reported 8437 cases with a 9.6% case fatality rate. The disease was caused by a previously unrecognized coronavirus, SARS-CoV. Drawing on experience with animal coronavirus vaccines, several vaccine candidates have been developed and evaluated in pre-clinical trials. Available data suggest that vaccines should be based on the the 180kDa viral spike protein, S, the only significant neutralization antigen capable of inducing protective immune responses in animals. In the absence of clinical cases of SARS, candidate vaccines should be evaluated for efficacy in animal models, and although it is uncertain whether the United States Food and Drug Administration's "animal rule" would apply to licensure of a SARS vaccine, it is important to develop standardized animal models and immunological assays in preparation for this eventuality. This report summarizes the recommendations from a WHO Technical Meeting on Animal Models and Antibody Assays for Evaluating Candidate SARS Vaccines held on 25-26 August 2005 in South Mimms, UK, provides guidance on the use of animal models, and outlines the steps to develop standard reagents and assays for immunological evaluation of candidate SARS vaccines.

  9. Special issue of selected papers from the second UK-Japan bilateral Workshop and First ERCOFTAC Workshop on Turbulent Flows Generated/Designed in Multiscale/Fractal Ways, London, March 2012

    NASA Astrophysics Data System (ADS)

    Laizet, Sylvain; Sakai, Yasuhiko; Christos Vassilicos, J.

    2013-12-01

    This special issue of Fluid Dynamics Research includes nine papers which are based on nine of the presentations at the Second UK-Japan bilateral Workshop and First ERCOFTAC Workshop on 'Turbulent flows generated/designed in multiscale/fractal ways: fundamentals and applications' held from 26 to 27 March 2012 at Imperial College London, UK. The research area of fractal-generated turbulent flows started with a chapter published in 2001 in one of the conference proceedings which came out of the 1999 Isaac Newton Institute 6 month Programme on Turbulence in Cambridge (UK). However, the first results which formed the basis of much of the work reported in this special issue started appearing from 2007 onwards and progress since then could perhaps be described as not insignificant. Research in this area has resulted in the following six notable advances: (a) the definition of two new length-scales characterizing grid-generated turbulence; (b) enhanced and energy-efficient stirring and scalar transfer by fractal grid and fractal openings/flanges with applications, in particular, to improved turbulence generation for combustion; (c) the non-equilibrium turbulent dissipation law; (d) non-equilibrium axisymmetric wake laws; (e) insights into the dependence of drag forces and vortex shedding on the fractal geometry of fractal objects and simulation methods for the calculation of drag of fractal trees; and (f) the invention and successful proof of concept of fractal spoilers and fractal fences. The present special issue contains papers directly related to these advances and can be seen as a reflection of the current research in the field of fractal-generated turbulent flows and their differences and commonalities with other turbulent flows. The financial support from the Japan Society for the Promotion of Science has been decisive for the organization and success of this workshop. We are also grateful to ERCOFTAC who put in place the EU-wide Special Interest Group on multiscale

  10. International Health and Tropical Medicine 08: Proceedings of a Residential Meeting of the Royal Society of Tropical Medicine and Hygiene, 17-19 September 2008, Brighton, UK.

    PubMed

    Newport, Melanie J; Lang, Trudie

    2009-11-01

    The Royal Society of Tropical Medicine and Hygiene held a residential meeting from 17-19 September 2008. Over 250 delegates from a diverse range of backgrounds and experience convened in Brighton, UK for three days of talks and discussions on a wide variety of themes. Topics ranged from tropical and neglected infectious diseases through to other disorders that whilst not traditionally associated with low income countries pose an increasing challenge; chronic diseases, mental health disorders and problems arising from conflict and poverty combined. The meeting represented the change in focus at RSTMH from tropical infectious diseases towards global health in its broadest sense.

  11. Monitoring CO2 and CH4 concentrations in London, UK using a rooftop atmospheric measurement network and an atmospheric chemistry-transport model

    NASA Astrophysics Data System (ADS)

    Boon, Alex; Broquet, Gregoire; Clifford, Debbie; Chevallier, Frederic; Butterfield, David; Pison, Isabelle; Ciais, Phillipe

    2014-05-01

    A rapidly developing research field is the development of monitoring networks and data assimilation systems to provide an optimal estimate of urban greenhouse gases based on both observations and the output of a chemistry-transport model driven by current emissions inventories. A key first step in development of this methodology is to evaluate the ability of the chemistry-transport model to simulate observations at the chosen measurement sites. In this study, funded by Astrium Services SAS, a network comprising four state-of-the-art atmospheric sensors was placed on rooftop sites in and around London during the summer of 2012. Two sites were located in the inner city and two 'background' sites (one suburban and one rural) were positioned to enable examination of the urban increment of GHG concentrations. The chemistry-transport model, CHIMERE, was run at 2 km resolution using temporally and spatially derived emissions inventories from the National Atmospheric Emissions Inventory (NAEI), driven by European Centre for Medium-Range Weather Forecasts (ECMWF) meteorology. Here, we focus on the analysis of the urban increments of total CO2, total CH4 and fossil fuel CO2 during the afternoon hours 12:00 to 17:00, aiming to identify the key sources of misfits between the model and the observations. Results showed there was improved agreement between the observed and modelled urban increments compared with total modelled and observed values for individual sites. This suggests that some of the misfits arose from the selection of appropriate boundary conditions for the model. However, there remained underestimation of the observed values and an inability of the model to simulate observed variability. The observations at the two inner city sites showed evidence of different contributions from local (<2 km-scale) sources, despite their proximity. A simple CO-based method was used to attribute fossil fuel CO2 from observations and showed that there were localised traffic based

  12. New insights from comprehensive on-road measurements of NOx, NO2 and NH3 from vehicle emission remote sensing in London, UK

    NASA Astrophysics Data System (ADS)

    Carslaw, David C.; Rhys-Tyler, Glyn

    2013-12-01

    In this paper we report the first direct measurements of nitrogen dioxide (NO2) in the UK using a vehicle emission remote sensing technique. Measurements of NO, NO2 and ammonia (NH3) from almost 70,000 vehicles were made spanning vehicle model years from 1985 to 2012. These measurements were carefully matched with detailed vehicle information data to understand the emission characteristics of a wide range of vehicles in a detailed way. Overall it is found that only petrol fuelled vehicles have shown an appreciable reduction in total NOx emissions over the past 15-20 years. Emissions of NOx from diesel vehicles, including those with after-treatment systems designed to reduce emissions of NOx, have not reduced over the same period of time. It is also evident that the vehicle manufacturer has a strong influence on emissions of NO2 for Euro 4/5 diesel cars and urban buses. Smaller-engined Euro 4/5 diesel cars are also shown to emit less NO2 than larger-engined vehicles. It is shown that NOx emissions from urban buses fitted with Selective Catalytic Reduction (SCR) are comparable to those using Exhaust Gas Recirculation for Euro V vehicles, while reductions in NOx of about 30% are observed for Euro IV and EEV vehicles. However, the emissions of NO2 vary widely dependent on the bus technology used. Almost all the NOx emission from Euro IV buses with SCR is in the form of NO, whereas EEV vehicles (Enhanced Environmentally friendly Vehicle) emit about 30% of the NOx as NO2. We find similarly low amounts of NO2 from trucks (3.5-12t and >12t). Finally, we show that NH3 emissions are most important for older generation catalyst-equipped petrol vehicles and SCR-equipped buses. The NH3 emissions from petrol cars have decreased by over a factor of three from the vehicles manufactured in the late 1990s compared with those manufactured in 2012. Tables of emission factors are presented for NOx, NO2 and NH3 together with uncertainties to assist the development of new emission

  13. Overall satisfaction, sexual function, and the durability of neophallus dimensions following staged female to male genital gender confirming surgery: the Institute of Urology, London U.K. experience

    PubMed Central

    Christopher, Nim A.; De Luca, Francesco; Spilotros, Marco; Ralph, David J.

    2014-01-01

    Background and purpose What factors influence transgender men’s decisions to undergo (and to not undergo) specific genital gender confirming surgeries (GCS) has not been described in the literature. Sexual function outcomes related to clitoral transposition and penile prosthesis placement is also not well described. Durability of neophallus dimensions after phalloplasty has not been described. A better understanding of these factors is necessary for pre-op counseling. We sought to assess patient genital-GCS related satisfaction, regret, pre/post-op sexual function, genital preferences, and genital measurements post-op. Materials and methods We evaluated ten female to male transgender patients who had previously undergone suprapubic pedicle-flap phalloplasty [suprapubic phalloplasty (SP); N=10] and 15 who had undergone radial artery forearm-flap phalloplasty [(RAP); N=15; 5/15 without and 10/15 with cutaneous nerve to clitoral nerve anastomosis] at our center (UK). We queried patients’ surgery related preferences and concerns, satisfaction, and sexual function pre/post-surgery, and accounted for whether patients had undergone clitoral transposition and/or cutaneous-to-clitoral nerve anastomosis. We measured flaccid and (where applicable) erect length and girth using a smart-phone app we designed. Results Mean age at surgery and follow-up for those that underwent SP was 35.1 and 2.23 years, and 34 and 6.8 for those that underwent RAP. Mean satisfaction scores were 9.1/10 and 9/10 for those that underwent SP and RAP, respectively. No patient (0%) regretted starting genital-GCS surgery. All (100%) patients that could achieve orgasm before GCS with clitoral transposition could achieve orgasm after surgery, and the vast majority reported preserved quality of erogenous sensation by our transposition technique. All (100%) RAP and 9/10 SP patients reported masturbation with their phallus. Inflatable penile prosthesis placement was not associated with decreased erogenous

  14. Analysis of the potential of near-ground measurements of CO2 and CH4 in London, UK, for the monitoring of city-scale emissions using an atmospheric transport model

    NASA Astrophysics Data System (ADS)

    Boon, Alex; Broquet, Grégoire; Clifford, Deborah J.; Chevallier, Frédéric; Butterfield, David M.; Pison, Isabelle; Ramonet, Michel; Paris, Jean-Daniel; Ciais, Philippe

    2016-06-01

    Carbon dioxide (CO2) and methane (CH4) mole fractions were measured at four near-ground sites located in and around London during the summer of 2012 with a view to investigating the potential of assimilating such measurements in an atmospheric inversion system for the monitoring of the CO2 and CH4 emissions in the London area. These data were analysed and compared with simulations using a modelling framework suited to building an inversion system: a 2 km horizontal resolution south of England configuration of the transport model CHIMERE driven by European Centre for Medium-Range Weather Forecasts (ECMWF) meteorological forcing, coupled to a 1 km horizontal resolution emission inventory (the UK National Atmospheric Emission Inventory). First comparisons reveal that local sources, which cannot be represented in the model at a 2 km resolution, have a large impact on measurements. We evaluate methods to filter out the impact of some of the other critical sources of discrepancies between the measurements and the model simulation except that of the errors in the emission inventory, which we attempt to isolate. Such a separation of the impact of errors in the emission inventory should make it easier to identify the corrections that should be applied to the inventory. Analysis is supported by observations from meteorological sites around the city and a 3-week period of atmospheric mixing layer height estimations from lidar measurements. The difficulties of modelling the mixing layer depth and thus CO2 and CH4 concentrations during the night, morning and late afternoon lead to focusing on the afternoon period for all further analyses. The discrepancies between observations and model simulations are high for both CO2 and CH4 (i.e. their root mean square (RMS) is between 8 and 12 parts per million (ppm) for CO2 and between 30 and 55 parts per billion (ppb) for CH4 at a given site). By analysing the gradients between the urban sites and a suburban or rural reference site, we

  15. London, England

    NASA Technical Reports Server (NTRS)

    2003-01-01

    For almost 2,000 years, the River Thames has served as the life force of London, capital of the United Kingdom and one of the world's most famous cities. In AD 43 the Romans established the trading settlement of Londinium at a favorable crossing point on the river. The Romans remained until the 5th century, when the city came under Saxon control. The early 17th century saw enormous growth, but the deadly plague of 1664 and 1665 ravaged the population, and in the following year the Great Fire, which burned for four days, destroyed most of the city. A public transportation system and other city services in the early 19th century eased many of the increasing urban problems of the burgeoning capital of the wealthy British Empire. After coping with the devastating effects of bombing during World War II and the gradual dismantling of the empire, London today thrives as a vital modern metropolis. London is one of 100 cities being studied using ASTER data to map and monitor urban use patterns and growth.

    This image was acquired on October 12, 2001 by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite. With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER images Earth to map and monitor the changing surface of our planet.

    ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.

    The broad spectral coverage and high spectral resolution of ASTER will provide scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats

  16. System-level and patient-level explanations for non-attendance at diabetic retinopathy screening in Sutton and Merton (London, UK): a qualitative analysis of a service evaluation

    PubMed Central

    Strutton, R; Du Chemin, A; Stratton, I M; Forster, A S

    2016-01-01

    Objectives Non-attendance at diabetic retinopathy screening has financial implications for screening programmes and potential clinical costs to patients. We sought to identify explanations for why patients had never attended a screening appointment (never attendance) in one programme. Design Qualitative analysis of a service evaluation. Setting One South London (UK) diabetic eye screening programme. Participants and procedure Patients who had been registered with one screening programme for at least 18 months and who had never attended screening within the programme were contacted by telephone to ascertain why this was the case. Patients’ general practices were also contacted for information about why each patient may not have attended. Framework analysis was used to interpret responses. Results Of the 296 patients, 38 were not eligible for screening and of the 258 eligible patients, 159 were not contactable (31 of these had phone numbers that were not in use). We obtained reasons from patients/general practices/clinical notes for non-attendance for 146 (57%) patients. A number of patient-level and system-level factors were given to explain non-attendance. Patient-level factors included having other commitments, being anxious about screening, not engaging with any diabetes care and being misinformed about screening. System-level factors included miscommunication about where the patient lives, their clinical situation and practical problems that could have been overcome had their existence been shared between programmes. Conclusions This service evaluation provides unique insight into the patient-level and system-level reasons for never attendance at diabetic retinopathy screening. Improved sharing of relevant information between providers has the potential to facilitate increased uptake of screening. Greater awareness of patient-level barriers may help providers offer a more accessible service. PMID:27194319

  17. Developing a new specialty – sport and exercise medicine in the UK

    PubMed Central

    Cullen, Michael

    2010-01-01

    Sports physicians have existed since ancient times. However as a recognised specialty, sports medicine is a relatively new discipline and even today very few countries have formal postgraduate training programmes which allow doctors to pursue a career in this discipline. This paper outlines the development of sport and exercise medicine in the United Kingdom, describing the journey leading to specialty recognition in 2005 and the progress being made towards establishing it as an integral component of the National Health Service in the 21st century. PMID:24198537

  18. The medicinal use of cannabis in the UK: results of a nationwide survey.

    PubMed

    Ware, M A; Adams, H; Guy, G W

    2005-03-01

    The use of cannabis for medical purposes is a controversial but an important topic of public and scientific interest. We report on the results of a self-administered questionnaire study conducted in the United Kingdom between 1998 and 2002. The questionnaire consisted of 34 items and included demographic data, disease and medication use patterns and cannabis use profiles. Subjects were self-selected; 3663 questionnaires were distributed and 2969 were returned [1805 (60.9%) women, mean age 52.7 years (SD 12.7)]. Medicinal cannabis use was reported by patients with chronic pain (25%), multiple sclerosis and depression (22% each), arthritis (21%) and neuropathy (19%). Medicinal cannabis use was associated with younger age, male gender and previous recreational use (p < 0.001). While caution must be exercised in interpreting these data, they point to the need for clinical studies of cannabis and cannabinoids with standardised and quality-controlled products.

  19. A survey of the role of the UK physicist in nuclear medicine: a report of a joint working group of the British Institute of Radiology, British Nuclear Medicine Society, and the Institute of Physics and Engineering in Medicine.

    PubMed

    Tindale, W B; Thorley, P J; Nunan, T O; Lewington, V; Shields, R A; Williams, N R

    2003-01-01

    Guidelines for the provision of physics support to nuclear medicine were published in 1999 by a joint working group of the British Institute of Radiology, the British Nuclear Medicine Society, and the Institute of Physics and Engineering in Medicine. Following publication of the guidelines, a survey was conducted by the working group to gather data on the actual level of physicist support in UK hospitals of different types and on the activities undertaken by physicists. The data were collected in the 12 months following the publication of guidelines and cover different hospital models and seven UK regions. The results provide evidence that many of the smaller units - small teaching hospitals and, particularly, small district general hospitals - have insufficient physics support. Although, on average, there is good agreement between the guidelines and the survey data for medium and large district general hospitals, there is wide variation in the level of physics provision between hospitals delivering apparently similar services. This emphasizes the need for national guidelines, against which institutions may be bench-marked and which may be used as a recommendation for the staffing levels necessary to ensure services are delivered safely and standards are not compromised. The complexity and variety of workload is an important factor in determining the level of physics support. As services develop, it is vital that this aspect is recognized to ensure that appropriate resources are available for the required physics input, even if any new service represents only a modest clinical throughput in terms of patient numbers.

  20. UK Parkinson's Excellence Network: empowering service improvement across the UK.

    PubMed

    Burn, David

    2015-01-01

    Parkinson's UK, together with leading Parkinson's professionals, has set up the UK Parkinson's Excellence Network to bring together the passion and expertise of leading clinicians with the strategic leadership and resources of Parkinson's UK underpinned by the voice of people affected by Parkinson's. Launched in London in February 2015, the Excellence Network aims to drive sustainable improvements in health and social care services. It will provide a more strategic approach to clinical development so that Parkinson's services across health and social care can be transformed to provide the best quality care across the UK.

  1. News Astronomy: Science and beauty combined Africa: Physics technicians offer valuable skills Conference: ESERA2013 brings researchers together in Cyprus Physics Olympiad: UK team bring home more medals from the Physics Olympics in Copenhagen Physics Tournament: IOC backs Shrewsbury to host IYPT 2014 Conference: MPTL18 looks at the latest multimedia developments Workshop: The selective absorption of light Science on Stage: Illuminating Science Education in London in 2015

    NASA Astrophysics Data System (ADS)

    2013-11-01

    Astronomy: Science and beauty combined Africa: Physics technicians offer valuable skills Conference: ESERA2013 brings researchers together in Cyprus Physics Olympiad: UK team bring home more medals from the Physics Olympics in Copenhagen Physics Tournament: IOC backs Shrewsbury to host IYPT 2014 Conference: MPTL18 looks at the latest multimedia developments Workshop: The selective absorption of light Science on Stage: Illuminating Science Education in London in 2015

  2. The prevalence of comorbidities among people living with HIV in Brent: a diverse London Borough

    PubMed Central

    Lorenc, Ava; Lorigan, James; Jowata, Mohamade; Brook, Gary; Banarsee, Ricky

    2014-01-01

    Background HIV has changed from a rapidly deteriorating illness to a complex chronic disease, with increasing incidences of comorbidity, including cancer, and liver, lung and cardiovascular diseases. North West London has 6719 individuals living with the human immunodeficiency virus (HIV), 873 of whom reside in the London Borough of Brent. Traditionally, commissioning services have focused on HIV therapy alone without considering how comorbidity affects treatment outcome and total service costs. Setting The setting for the study was NHS Brent Primary Care Trust, London UK. Question What associated comorbidities are present in people in Brent (London, UK) living with HIV, and how common are they? Methods A point-prevalence audit of retrospective data was conducted on all HIV-positive patients in Brent (financial year 2011/12). Data were collected from genito-urinary medicine (GUM) services, community services and general practitioners (GPs) on HIV diagnosis, patient demographics and past/current comorbidities: hepatitis B and C, cardiovascular disease, diabetes and mental health disorders. Results This study identified that 29% of people living with HIV/AIDS (PLWHA) in Brent have at least one comorbidity. The most common was hepatitis, followed by mental health disorders and cardiovascular disease (CVD). Comorbidity was more likely in older male patients (in particular CVD and diabetes) and White patients (except for diabetes which was more common in Asian groups). Discussion/Conclusion Many PLWHA in Brent suffer from a number of other conditions, which appear largely independent of HIV. Findings confirm the need to treat HIV as a long-term condition, including patient education, empowerment and encouraging self-management. The multi-morbidity of many PLWHA suggests a role for both primary care and collaborative, holistic, patient-centred and individualised healthcare. Service providers and commissioners need to consider comorbidities in their treatment of and

  3. Investigation of social, demographic and health variations in the usage of prescribed and over-the-counter medicines within a large cohort (South Yorkshire, UK)

    PubMed Central

    Green, Mark A; Little, Emma; Cooper, Richard; Relton, Clare; Strong, Mark

    2016-01-01

    Objectives Prescribed and over-the-counter (non-prescribed) medicine usage has increased in recent years; however, there has been less investigation of the socioeconomic predictors of use. This has been due to a lack of data, especially for over-the-counter medicines. Our study aims to understand how prescribed and over-the-counter medicine patterns vary by demographic, social and health characteristics within a large population cohort. Design Cross-sectional data analysis. Setting South Yorkshire, UK. Participants 27 806 individuals from wave 1 of the Yorkshire Health Study (2010–2012). Measures Individuals self-reported each medicine they were taking and whether each was prescribed or not. The medicines were grouped into 14 categories (eg, cardiovascular system, infection, contraception). Negative binomial regression models were used to analyse the count of medicine usage. We included demographic (age, gender, ethnicity), social (education), health-related (body mass index, smoking, alcohol consumption, physical activity) factors and chronic health conditions (eg, stroke, anxiety and heart disease) in our analyses. Results 49% of men and 62% of women were taking medicine with the majority of this prescribed (88% and 83%, respectively). Health conditions were found to be positively associated with prescribed medicine usage, but mixed in their associated with over-the-counter medicines. Educational attainment was negatively associated with prescribed and positively associated with over-the-counter usage. Conclusions Our study addresses a dearth of evidence to provide new insights into how behaviours in medicine usage vary by demographic, social and health-related factors. Differences in over-the-counter medicine usage by educational attainment may help our understanding of the determinants of health inequalities. PMID:27683515

  4. The doctor's medicine and the ambiguity of amulets: life and suffering among Bangladeshi psychiatric patients and their families in London – an interview study – 1

    PubMed Central

    Littlewood, Roland; Dein, Simon

    2013-01-01

    An interview study of 44 Bangladeshi patients and relatives in London demonstrated simultaneous trust in psychiatrists as well as in the widespread use of healing amulets. At the same time, local Islamic clerics and traditional healers were seen by many with some degree of suspicion. The authors offer an interpretation in which local healers and their methods are regarded ambivalently: the more distant biomedical framework fits with the newer modernising ‘High’ Islam (literate, scripturalist, puritanical, unitarian, urban, clerical, perhaps masculinist), as opposed to Hindu-inflected traditional Sufi Islam in Bangladesh (peasant, popular, syncretic, saintly, magical, ecstatic and possibly more sympathetic to women's experience). PMID:23998259

  5. The doctor's medicine and the ambiguity of amulets: life and suffering among Bangladeshi psychiatric patients and their families in London--an interview study--1.

    PubMed

    Littlewood, Roland; Dein, Simon

    2013-01-01

    An interview study of 44 Bangladeshi patients and relatives in London demonstrated simultaneous trust in psychiatrists as well as in the widespread use of healing amulets. At the same time, local Islamic clerics and traditional healers were seen by many with some degree of suspicion. The authors offer an interpretation in which local healers and their methods are regarded ambivalently: the more distant biomedical framework fits with the newer modernising 'High' Islam (literate, scripturalist, puritanical, unitarian, urban, clerical, perhaps masculinist), as opposed to Hindu-inflected traditional Sufi Islam in Bangladesh (peasant, popular, syncretic, saintly, magical, ecstatic and possibly more sympathetic to women's experience).

  6. Assessing the sources and bioaccessibility of Lead in Soils from London

    NASA Astrophysics Data System (ADS)

    Cave, Mark R.; Wragg, Joanna; Chenery, Simon

    2013-04-01

    The lead content of soil is important since it is toxic to humans and particularly because children tend to more readily absorb lead than do adults: children absorb up to 40% into the bloodstream from ingested or inhaled lead, versus 5-15% in adults. Studies have shown that relatively low concentrations of lead in blood can lead to significant decrease in IQ of children (e.g. Jakubowski, 2011) leading to neuropathy and hypertension in adults. The British Geological Survey has recently completed a systematic high-density geochemical soil survey of the Greater London Area (GLA) in which over 6000 surface soil samples were collected and analysed for 50 elements. The Pb content of the soils range from 11 mg/kg to greater than 10000 mg/kg with mean and median values of 301 and 185 mg/kg, respectively. The ingestion bioaccessible fraction of Pb was measured using an in-vitro bioaccessibility test showing that 68% of the total Pb in London soils is bioaccessible. Measurement of Pb isotopic ratios in selected soils matched with those found in London air particulates and, to a lesser extent, with petrol lead. Self modelling mixture resolution of the 50 element geochemical data set was used to identify geochemically distinct components in the data with Pb being associated with 11 of the components which were of both natural and anthropogenic origin. Relationships between the soil components, the bioaccessible fraction and the Pb isotope ratios provided an indication of the sources of mobile lead in the London soils. References JAKUBOWSKI, M. 2011. Low-level environmental lead exposure and intellectual impairment in children - the current concepts of risk assessment. International Journal of Occupational Medicine and Environmental Health, Vol. 24, 1-7. APPLETON, J D, CAVE, M R, and WRAGG, J. 2012. Modelling lead bioaccessibility in urban topsoils based on data from Glasgow, London, Northampton and Swansea, UK. Environmental Pollution, Vol. 171, 265-272.

  7. Are Londoners Prepared for an Emergency? A Longitudinal Study Following the London Bombings

    PubMed Central

    Rubin, James; Amlôt, Richard; Simpson, John; Wessely, Simon

    2008-01-01

    The UK government sees increasing individual preparedness as a priority, but the level of preparedness of people in the UK for a large-scale emergency is not known. The London bombings of July 7, 2005, affected many Londoners and may have altered their sense of vulnerability to a future terrorist attack. We used a longitudinal study design to assess individual preparedness within the same sample of Londoners at 2 points in time: immediately after the bombings (T1) and 7 to 8 months later (T2). A demographically representative sample of 1,010 Londoners participated in a phone interview at T1. Subsequently, at T2, 574 of the same people participated in a follow-up phone interview. At T1 51% of Londoners had made 4 or more relevant emergency plans; 48% had gathered 4 or more relevant supplies in case of emergency. There was evidence of increased preparedness at T2, by which time 90% had made 4 or more emergency plans. Ethnicity, low social status, and having felt a sense of threat during the bombings predicted increased preparedness between T1 and T2. Women in general, and women of low social status in particular, perceived themselves to be unprepared in the event of a future terrorist attack. In summary, Londoners show moderate levels of emergency preparedness, which increased following the London bombings. Although we cannot know whether this association is causal, the prospective nature of the study increases the likelihood that it is. However, preparedness is still patchy, and there are important demographic associations with levels of preparedness and perception of vulnerability. These findings have implications for future development of individual and community emergency preparedness policy. PMID:19117430

  8. Variation in assessment and standard setting practices across UK undergraduate medicine and the need for a benchmark

    PubMed Central

    2015-01-01

    Objectives The principal aim of this study is to provide an account of variation in UK undergraduate medical assessment styles and corresponding standard setting approaches with a view to highlighting the importance of a UK national licensing exam in recognizing a common standard. Methods Using a secure online survey system, response data were collected during the period 13 - 30 January 2014 from selected specialists in medical education assessment, who served as representatives for their respective medical schools. Results Assessment styles and corresponding choices of standard setting methods vary markedly across UK medical schools. While there is considerable consensus on the application of compensatory approaches, individual schools display their own nuances through use of hybrid assessment and standard setting styles, uptake of less popular standard setting techniques and divided views on norm referencing. Conclusions The extent of variation in assessment and standard setting practices across UK medical schools validates the concern that there is a lack of evidence that UK medical students achieve a common standard on graduation. A national licensing exam is therefore a viable option for benchmarking the performance of all UK undergraduate medical students. PMID:26520472

  9. The London Schools Planetarium

    ERIC Educational Resources Information Center

    Richards-Jones, P.

    1973-01-01

    Summarizes the scientific activities conducted at the London Schools Planetarium by students of primary and secondary schools and of teacher colleges. Included is a table illustrating the astronomical background of student teachers. (CC)

  10. Materials modelling in London

    NASA Astrophysics Data System (ADS)

    Ciudad, David

    2016-04-01

    Angelos Michaelides, Professor in Theoretical Chemistry at University College London (UCL) and co-director of the Thomas Young Centre (TYC), explains to Nature Materials the challenges in materials modelling and the objectives of the TYC.

  11. Overseas Chinese students in the UK: patterns and correlates of their use of Western and traditional Chinese medicine.

    PubMed

    Bishop, Felicity L; Lim, Chiw Yeh; Leydon, Geraldine M; Lewith, George T

    2009-02-01

    We explored the correlates of use of TCM and WM by ethnic Chinese students in the UK. A questionnaire assessed key theoretical determinants of health services use. One hundred and seventy ethnic Chinese participants (international students at one university in the South of England) completed this questionnaire (presented in English and Chinese) assessing their demographic characteristics, health status, attitudes towards and use of TCM and WM. Participants were more likely to use WM than TCM when they were in the UK. Different variables predicted use of WM and TCM. The statistical predictors (demographic characteristics, health status, past behaviour, attitudes) explained modest but important proportions of the variance in use of WM (37%) and TCM (29%). In conclusion, this small exploratory study suggests a need for further research on the health care utilisation of this growing body of international students. Improved language support is needed for international students in UK health care settings.

  12. East London Experience with Enteric Fever 2007-2012

    PubMed Central

    Dave, Jayshree; Millar, Michael; Maxeiner, Horst; Freedman, Joanne; Meade, Rachel; Rosmarin, Caryn; Jordan, Matthew; Andrews, Nick; Holliman, Richard; Sefton, Armine

    2015-01-01

    Purpose The clinical presentation and epidemiology for patients with enteric fever at two hospitals in East London during 2007–2012 is described with the aim to identify preventive opportunities and to reduce the cost of treatment. Methods A retrospective analysis of case notes from patients admitted with enteric fever during 2007 to 2012 with a microbiologically confirmed diagnosis was undertaken. Details on clinical presentation, travel history, demographic data, laboratory parameters, treatment, patient outcome and vaccination status were collected. Results Clinical case notes were available for 98/129 (76%) patients including 69 Salmonella enterica serovar Typhi (S. Typhi) and 29 Salmonella enterica serovar Paratyphi (S. Paratyphi). Thirty-four patients (35%) were discharged from emergency medicine without a diagnosis of enteric fever and then readmitted after positive blood cultures. Seventy-one of the 98 patients (72%) were UK residents who had travelled abroad, 23 (23%) were foreign visitors/new entrants to the UK and four (4%) had not travelled abroad. Enteric fever was not considered in the initial differential diagnosis for 48/98 (49%) cases. The median length of hospital stay was 7 days (range 0–57 days). The total cost of bed days for managing enteric fever was £454,000 in the two hospitals (mean £75,666/year). Median time to clinical resolution was five days (range 1–20). Seven of 98 (7%) patients were readmitted with relapsed or continued infection. Six of the 71 (8%) patients had received typhoid vaccination, 34 (48%) patients had not received vaccination, and for 31 cases (44%) vaccination status was unknown. Conclusions Further interventions regarding education and vaccination of travellers and recognition of the condition by emergency medicine clinicians in travellers to South Asia is required. PMID:25790017

  13. A survey of UK dental health professionals using a medicines information service: what questions do they ask and do they get useful answers?

    PubMed

    McEntee, J E; Henderson, S L; Rutter, P M; Rutter, J; Davis, H J; Randall, C J

    2011-07-08

    Dentists prescribe a limited range of medicines but it is important that they consider the effects of all medicines their patients are taking when providing dental care. In the UK, a national medicines information (UKMi) service funded by the National Health Service is available to advise health professionals on prescribing and to support evidence-based practice. This paper presents the results of a survey of 151 dental health professionals who contacted the UKMi service for advice. Enquiries most commonly involved antibiotics (32%), but dental health professionals also asked for advice on legal issues relating to medicines (10%), and on managing patients receiving bisphosphonates (9%), local anaesthetics (6%) and antiplatelet drugs (5%). One hundred and forty-six (97%) enquirers used the advice provided: for managing current patients, planning the care of future patients, for continuing professional development and teaching others. Two thirds of enquirers used the information provided to check if current or proposed management was appropriate, one half to change therapy and over one quarter to identify, manage or avoid adverse effects or drug interactions.

  14. Continuous monitoring of carbon dioxide, methane and carbon monoxide west of London, UK: use of long term records and isotopes to identify changes in source emissions in the regional and local atmosphere

    NASA Astrophysics Data System (ADS)

    Fisher, R.; Lowry, D.; Sriskantharajah, S.; Nisbet, E.

    2003-04-01

    The Royal Holloway atmospheric laboratory measures CH4, CO2 and CO continuously, and δ 13C of methane is also measured in spot samples, all to high precision and accuracy. The records date back to 1995 for CH4, 1996 for CO and 1999 for CO2. The collection site is on a campus rooftop, at Egham, on the first hill west of London. This allows sampling both of relatively clean background air from the SW and London air from the east. During still anticyclonal events, gentle daytime SW winds are often replaced by nocturnal easterlies from the urban heat island. Overall, in the past 2-3 years the major pollution events appear to have been less marked than in previous years: this may be meteorological accident (i.e. more wet windy Atlantic-type weather; less anticyclonic and Eurasian air), but may also record improvement in urban air quality. For example, the annual averaged CO concentration recorded at the Egham site dropped from 580 ppb for 1997 to 380 ppb for 2001. The yearly concentration of methane has also decreased since the records began from 2032ppb in 1996 to 1995ppb in 2001. On a daily time scale, by using CH4 emissions as a relative constant the effects of meteorological variability can be removed from the dataset and the periods of excess CO2 and CO calculated. These correspond closely with rush hour traffic periods with minimum excess at 04:00 GMT. Deviations from normal abundance ratios between CO2, CO and CH4 identify distinct emission traits in each gas. High precision isotopic analysis of methane in air samples allows changing source emissions to be identified. The methane record has been compared with the Atlantic background CH4 concentrations and δ 13C recorded at Mace Head. The methane concentration in air arriving at Royal Holloway from the SW is commonly 25-30 ppb greater than at Mace Head and there is a small enrichment in δ 13C (0-0.2 permil). During anticyclonic events the isotopes of CH4 and CO2 can be used to identify local sources and the

  15. How a Regional Broker Can Improve Industry Demand for University Interaction: A Case Study of the London Technology Network

    ERIC Educational Resources Information Center

    Reid, Peter; Schofield, Matt

    2006-01-01

    UK university research produces highly cited publications (DTI, 2004), but demand from UK business for commercial ideas from academia is weak (HM Treasury, 2003). This paper reviews factors in the development of one regional UK technology broker, the London Technology Network (LTN), which has achieved significant and audited business demand. The…

  16. 117. Thames River Bridge. New London, New London Co., CT. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    117. Thames River Bridge. New London, New London Co., CT. Sec. 4215, MP 124.09. - Northeast Railroad Corridor, Amtrak Route between New York/Connecticut & Connecticut/Rhode Island State Lines, New Haven, New Haven County, CT

  17. Aspirin in the 21st century-common mechanisms of disease and their modulation by aspirin: a report from the 2015 scientific conference of the international aspirin foundation, 28 August, London, UK.

    PubMed

    Smith, Tom; Hutchison, Pippa; Schrör, Karsten; Clària, Joan; Lanas, Angel; Patrignani, Paola; Chan, Andrew T; Din, Farhat; Langley, Ruth; Elwood, Peter; Freedman, Andrew; Eccles, Ron

    2015-01-01

    Professor Peter Rothwell of Oxford University chaired the annual Scientific Conference of the International Aspirin Foundation in London on 28 August 2015. It took the form of four sessions. Aspirin has more than one action in its effects on disease. Its acetylation of cyclooxygenase 2 (COX-2) in platelets leads to the blockade of pro-inflammatory chemicals and generation of anti-inflammatory mediators and increase in nitrous oxide (NO) production, which helps to preserve arterial endothelium. But platelets are not its only target. There is now evidence that aspirin has a direct antitumour effect on intestinal mucosal cells that block their potential transformation into cancer cells. Randomised placebo-controlled trials (RCTs) in people with histories of colorectal neoplasia have shown that aspirin reduces the risk of recurrent adenomas and reduces long-term cancer incidence in patients with Lynch syndrome. Among women given aspirin for cardiovascular disease, there were fewer cancers than in those given placebo. Epidemiological evidence has suggested that aspirin treatment after cancer is diagnosed reduces the incidence of metastases and prolongs survival, and long-term studies of anticancer treatment with aspirin are under way to confirm this. Apart from cancer studies, aspirin use is now firmly established as treatment for antiphospholipid syndrome (Hughes syndrome) and is being used to prevent and treat the heightened risk of cardiovascular disease in diabetes mellitus and in patients with HIV.

  18. The wrong London

    NASA Astrophysics Data System (ADS)

    Griffiths, Hugh; Tong, Kenneth

    2010-01-01

    Your article "Optics pioneers scoop Nobel prize" (November 2009 pp6-7) incorrectly states that Charles Kao, who shared the 2009 Nobel Prize for Physics with Willard Boyle and George Smith, received his PhD from Imperial College London.

  19. The use of biomedicine, complementary and alternative medicine, and ethnomedicine for the treatment of epilepsy among people of South Asian origin in the UK

    PubMed Central

    Rhodes, Penny J; Small, Neil; Ismail, Hanif; Wright, John P

    2008-01-01

    Background Studies have shown that a significant proportion of people with epilepsy use complementary and alternative medicine (CAM). CAM use is known to vary between different ethnic groups and cultural contexts; however, little attention has been devoted to inter-ethnic differences within the UK population. We studied the use of biomedicine, complementary and alternative medicine, and ethnomedicine in a sample of people with epilepsy of South Asian origin living in the north of England. Methods Interviews were conducted with 30 people of South Asian origin and 16 carers drawn from a sampling frame of patients over 18 years old with epilepsy, compiled from epilepsy registers and hospital databases. All interviews were tape-recorded, translated if required and transcribed. A framework approach was adopted to analyse the data. Results All those interviewed were taking conventional anti-epileptic drugs. Most had also sought help from traditional South Asian practitioners, but only two people had tried conventional CAM. Decisions to consult a traditional healer were taken by families rather than by individuals with epilepsy. Those who made the decision to consult a traditional healer were usually older family members and their motivations and perceptions of safety and efficacy often differed from those of the recipients of the treatment. No-one had discussed the use of traditional therapies with their doctor. The patterns observed in the UK mirrored those reported among people with epilepsy in India and Pakistan. Conclusion The health care-seeking behaviour of study participants, although mainly confined within the ethnomedicine sector, shared much in common with that of people who use global CAM. The appeal of traditional therapies lay in their religious and moral legitimacy within the South Asian community, especially to the older generation who were disproportionately influential in the determination of treatment choices. As a second generation made up of people of

  20. "Every morning before you open the door you have to watch for that brown envelope": complexities and challenges of undertaking oral history with Ethiopian forced migrants in London, UK.

    PubMed

    Palmer, David

    2010-01-01

    The experience, "voice," and perceptions of the "individual refugee" is conspicuous by its virtual absence from academic research. The few studies dealing with black adn minority ethnic experiences from an emic perspective in relation to mental health do not specifically refer to refugees or asylum seekers. This article explores the use of oral history techniques when researching Ethiopian forced migrants in the U.K. Based on two pilot research projects which explored Ethiopian culture and experience in reference to mental health adn well-being, it will focus on some of the complexities and challenges encountered. This article acknowledges the need for an understanding of cultural traditions as well as history and experience when planning and implementing such research as this proved to be an essential part of the research process, ensuring that individual stories and truths were allowed to evolve. The oral history approach for this research therefore ensured that the experiential knowledge of the Ethiopian forced migrant participants was given space, authenticity, and validity.

  1. Atmospheric merger in London

    NASA Astrophysics Data System (ADS)

    At the invitation of Imperial College, the Laboratory for Planetary Atmospheres, University College London, will be integrated in August with the Atmospheric Physics Group to form a single teaching and research unit. The new group, to be located at Imperial College, will be headed by Garry Hunt.The new group will possess a balanced research program in the observational and interpretative aspects of atmospheric physics. The existing Imperial College group actively researches cumulonimbus dynamics and climate modeling.

  2. Clean Air for London (CLEARFLO) Final Campaign Summary

    SciTech Connect

    Worsnop, D. R.; Williams, L. R.; Herndon, S. C.; Dubey, M.; Ng, N. L.; Thornton, J.; Knighton, B.; Coulter, R.; Prévôt, Ash

    2016-03-01

    This field campaign funded the participation of scientists from seven different research groups and operated over thirty instruments during the Winter Intensive Operating Period (January-February 2012) of the Clean Air for London (ClearfLo) campaign. The campaign took place at a rural site in Detling, UK, 45 kilometers southeast of central London. The primary science questions for the ClearfLo winter IOP (intensive operational periods) were: 1) “what is the urban increment of particulate matter (PM) and other pollutants in the greater London area?” and 2) “what is the contribution of solid fuel use for home heating to wintertime PM?” An additional motivation for the Detling measurements was the question of whether coatings on black carbon particles enhance absorption.

  3. A practical approach to Events Medicine provision.

    PubMed

    Smith, Susan P; Cosgrove, Joseph F; Driscoll, Peter J; Smith, Andrew; Butler, John; Goode, Peter; Waldmann, Carl; Vallis, Christopher J; Topham, Fiona; Mythen, Michael Monty

    2016-09-09

    In the past three decades, mass casualty incidents have occurred worldwide at multiple sporting events and other mass gatherings. Organisational safety and healthcare provision can consequently be scrutinised post-event. Within the UK, such incidents in the 1980s provided incentives to improve medical services and subsequent high profile UK-based international sporting events (London Olympics and Paralympics 2012, Glasgow Commonwealth Games 2014, Rugby World Cup 2015) added a further catalyst for developing services. Furthermore in the aftermath of the abandoned France versus Germany association football match at the Stade de France (Paris Terrorist Attacks, November 2015) and the 2016 UK report from HM Coroner on the Hillsborough Inquest, medical cover at sporting events is being further reviewed. Doctors providing spectator cover therefore need to have an awareness of their likely roles at sporting venues. Formal guidance exists in many countries for the provision of such cover but remains generic even though Events Medicine is increasingly recognised as a necessary service. The current evidence base is limited with best practice examples often anecdotally cited by acute care specialists (eg, emergency medicine) who provide cover. This article is therefore intended to present an overview for doctors of the knowledge and skills required to treat ill and injured spectators and enable them to adequately risk-assess venues in cooperation with other health and safety providers, including preparation for a major incident. It also gives guidance on how activity can be adequately assessed and how doctors can have management roles in Events Medicine.

  4. The role of the Faculty of Public Health (Medicine) in developing a multidisciplinary public health profession in the UK.

    PubMed

    Griffiths, Sian; Crown, June; McEwen, Jim

    2007-06-01

    The Faculty of Public Health (FPH) started out its life as the Faculty of Community Medicine. Its initial membership was drawn from the ranks of Medical Officers of Health (MOsH), medical administrators and consultants working in communicable disease. Born under the aegis of the three Royal Colleges of Physicians, it was de facto for members of the medical profession. This was despite the intention of some of the prime movers in its creation that its membership should reflect the multidisciplinary nature of specialist public health. As such, whilst the Faculty's establishment was indeed a triumph, the triumph was only partial, since many senior public health professionals were precluded from full membership. Over the years this situation has changed, but the road to the Faculty's current open policy, based on achieving public health excellence rather than holding a professional badge, has not been a smooth one. The fears of many medical members that the specialty would be down graded through opening up its membership posed successive presidents with many, often justifiable, challenges. In this article we, former presidents, reflect on the key events during our successive tenures.

  5. Lipoedema: the first UK patient survey.

    PubMed

    Evans, Suzanne

    2013-04-01

    Lipoedema UK was founded in 2012 by women with lipoedema and clinicians working in the Lymphoedema Service at St George's Hospital in London. Its patron is Professor Peter Mortimer, the UK's leading Lipoedema expert, and its nurse consultant is Sandy Ellis, who diagnoses and treats many women with Lipoedema in the UK and is also the nurse consultant in the St George's team. The charity's objectives are to educate doctors, health professionals and the public about lipoedema and its symptoms, so it may be diagnosed and treated earlier.

  6. London: An Art Teacher's Inspiration

    ERIC Educational Resources Information Center

    Guhin, Paula

    2012-01-01

    Often overshadowed in people's minds by Paris, London is truly an artist's jewel. The art and architecture, history, gardens and museums are inspiring, yes, but there's so much more to this ancient city. The performances, attractions and markets are a boon to the creative soul. London can be surprisingly inexpensive to visit. Gazing at statues,…

  7. Biomarkers research in Europe: focus on personalized medicine.

    PubMed

    Metodiev, Metodi V

    2011-09-01

    The sixth annual European Biomarkers Summit took place in London, UK, on 18-19 May 2011. It was part of a larger event, organized by Select Biosciences, with meetings on molecular diagnostics, single cell analysis and theranostics for personalized medicine. The Biomarkers Summit featured 17 invited talks from academics and industry researchers, a number of poster presentations and exhibitions from several companies marketing biomarker-related technologies and consumables. The focus was broad, covering various aspects of biomarker discovery, qualification, and applications, and a variety of diseases including cancer, neurodegenerative conditions and infectious diseases. Gene-based, as well as protein-based, platforms for biomarkers identification and analysis were discussed.

  8. Optical legacy of Imperial College London

    NASA Astrophysics Data System (ADS)

    Kidger Webb-Moore, Tina E.

    2016-10-01

    The Industrial Revolution, beginning primarily in the UK, generated an increasing need for highly skilled technical people. Throughout the 19th century, technical instruction increased dramatically and the formation of schools specializing in science and technology grew quickly. In England, there was much motivation in favour of a national prestige center for science and technology centered in London. Central among the motivating forces was Queen Victoria's husband, Prince Albert. Although there were already existing specialist science and technology institutions in major English cities, the growth of superior institutions in other countries within Europe, especially Germany and the Charlottenburg area of Berlin (e.g., the Berlin Technical High School), encouraged important English dignitaries to become more competitive with continental Europe. As a result of this strong continental motivation, several science and technology institutions were built in the south Kensington part of London during the latter half of the 19th century. Imperial College, founded at the start of the 20th century, was a culmination and consolidation of several of these 19th century English institutions. Optical science and technology was an early beneficiary of the founding of Imperial College. This paper will attempt to provide the reader with an understanding of how great was the influence of the optical section of Imperial College in the further development of the world's optical science and technology.

  9. Popular opinion leaders in London: a response to Kelly.

    PubMed

    Elford, J; Bolding, G; Sherr, L

    2004-02-01

    Controlled trials conducted in the USA provide clear evidence that peer education can bring about a reduction in high risk sexual behaviour among gay men. HIV prevention interventions that systematically identified, recruited, trained and engaged popular opinion leaders (POLs) made a significant impact on sexual behaviour at a community level in small US towns. However, recent trials conducted in the UK have failed to replicate these findings. A POL intervention in London made no significant impact at a community level on the risk behaviours of gay men. Jeffrey Kelly, one of the authors of the US studies, has identified nine core elements central to the popular opinion leader model. In Kelly's view 'the UK projects were not tests of the popular opinion leader model because they did not employ most of these POL core elements'. The absence of any significant impact of the UK programmes on sexual risk behaviour at a community level was not, therefore, surprising. In fact, the London POL project incorporated all the core elements into its design and succeeded in employing seven out of nine in its delivery. Attempts to employ all the core elements, however, were hampered by problems in recruiting popular opinion leaders as well as barriers to communication. Process evaluation revealed that it was these obstacles which limited diffusion. This in turn explained the absence of any impact of the London POL project on sexual risk behaviour at a community level. The obstacles to successful diffusion in London have provided a valuable opportunity for examining the processes that underlie the POL model. Our study raises the question as to whether social interventions shown to be effective in one setting, place or moment in time can be replicated in another.

  10. Looking into 'London'

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This mosaic image from the microscopic imager on the Mars Exploration Rover Opportunity shows the rock abrasion tool target, 'London.' The image was taken by the Mars Exploration Rover Opportunity on its 149th sol on Mars (June 24, 2004). Scientists 'read' the geology of the image from bottom to top, with the youngest material pictured at the bottom of the image and the oldest material in the layers pictured at the top. Millimeter-scale layers run horizontally across the exposed surface, with two sliced sphere-like objects, or 'blueberries' on the upper left and upper right sides of the impression. This material is similar to the evaporative material found in 'Eagle Crater.' However, the intense review of these layers in Endurance Crater is, in essence, deepening the water story authored by ancient Mars.

    In Eagle Crater, the effects of water were traced down a matter of centimeters. Endurance Crater's depth has allowed the tracing of water's telltale marks up to meters. Another process that significantly affects martian terrain is muddying the water story a bit. Although it is clear that the layers in Endurance were affected by water, it is also evident that Aeolian, or wind, processes have contributed to the makeup of the crater.

  11. The ClearfLo project - Understanding London's meteorology and composition

    NASA Astrophysics Data System (ADS)

    Belcher, Stephen; Bohnenstengel, Sylvia

    2014-05-01

    ClearfLo is a large multi-institutional project funded by the UK Natural Environment Research Council (NERC). ClearfLo established integrated measurements of meteorology, gaseous and particulate composition/loading of London's (UK) urban atmosphere in 2011 and 2012 to understand the processes underlying poor air quality. A new and unique long-term measurement infrastructure was established in London at street level, urban background and elevated sites and contrasted against rural locations to determine the urban increment in meteorology and pollution. This approach enables understanding the seasonal variations in the meteorology and composition together with the controlling processes. In addition two intensive observation periods (IOPs) provide more detail in winter 2012 and during the Olympics in summer 2012 focusing upon the vertical structure and evolution of the urban boundary layer, chemical controls on nitrogen dioxide and ozone production, in particular the role of volatile organic compounds, and processes controlling the evolution, size, distribution and composition of particulate matter. In this talk we present early analysis of the meteorology and air quality measurements within ClearfLo. In particular we show measurements that indicate the dominant regimes of London's boundary layer.

  12. Standardised versus individualised multiherb Chinese herbal medicine for oligomenorrhoea and amenorrhoea in polycystic ovary syndrome: a randomised feasibility and pilot study in the UK

    PubMed Central

    Flower, Andrew; Prescott, Philip; Wing, Trevor; Moore, Michael; Lewith, George

    2017-01-01

    Objectives To explore feasibility of a randomised study using standardised or individualised multiherb Chinese herbal medicine (CHM) for oligomenorrhoea and amenorrhoea in women with polycystic ovary syndrome (PCOS), to pilot study methods and to obtain clinical data to support sample size calculations. Design Prospective, pragmatic, randomised feasibility and pilot study with participant and practitioner blinding. Setting 2 private herbal practices in the UK. Participants 40 women diagnosed with PCOS and oligomenorrhoea or amenorrhoea following Rotterdam criteria. Intervention 6 months of either standardised CHM or individualised CHM, 16 g daily taken orally as a tea. Main outcome measures Our primary objective was to determine whether oligomenorrhoea and amenorrhoea were appropriate as the primary outcome measures for the main study. Estimates of treatment effects were obtained for menstrual rate, body mass index (BMI), weight and hirsutism. Data were collected regarding safety, feasibility and acceptability. Results Of the 40 participants recruited, 29 (72.5%) completed the study. The most frequently cited symptoms of concern were hirsutism, weight and menstrual irregularity. Statistically significant improvements in menstrual rates were found at 6 months within group for both standardised CHM (mean difference (MD) 0.18±0.06, 95% CI 0.06 to 0.29; p=0.0027) and individualised CHM (MD 0.27±0.06, 95% CI 0.15 to 0.39; p<0.001), though not between group (p=0.26). No improvements were observed for BMI nor for weight in either group. Improvements in hirsutism scores found within group for both groups were not statistically significant between group (p=0.09). Liver and kidney function and adverse events data were largely normal. Participant feedback suggests changing to tablet administration could facilitate adherence. Conclusions A CHM randomised controlled trial for PCOS is feasible and preliminary data suggest that both individualised and standardised

  13. Analyzing the Roles, Activities, and Skills of Learning Technologists: A Case Study from City University London

    ERIC Educational Resources Information Center

    Fox, Olivia; Sumner, Neal

    2014-01-01

    This article reports on a case study carried out at City University London into the role of learning technologists. The article examines how the role developed by providing points of comparison with a report on the career development of learning technology staff in UK universities in 2001. This case study identified that learning technologists…

  14. Teachers' Experiences of Autonomy in Continuing Professional Development: Teacher Learning Communities in London and Hong Kong

    ERIC Educational Resources Information Center

    Hargreaves, Eleanore; Berry, Rita; Lai, Y. C.; Leung, Pamela; Scott, David; Stobart, Gordon

    2013-01-01

    This paper examines teachers' experiences of autonomy as they undertook Continuing Professional Development (CPD) in the form of Teacher Learning Communities (TLCs) to develop Assessment for Learning (AfL). Participant teacher interview data were used from two parallel TLC projects, one in Hong Kong and one in London, UK. Autonomy was defined in…

  15. Medicines

    MedlinePlus

    ... better. In the United States, the Food and Drug Administration is in charge of assuring the safety ... prescription and over-the-counter medicines. Even safe drugs can cause unwanted side effects or interactions with ...

  16. Nicholas Culpeper (1616-1654): London's first general practitioner?

    PubMed

    Farthing, Michael J G

    2015-08-01

    Nicholas Culpeper is often regarded as an ill-disciplined, maverick, mid-17th century herbalist and the father of contemporary alternative medicine. There are elements of this statement that have some truth but to dismiss his contribution to the development of health provision in London at the time would be a great injustice. Culpeper did not complete his apprenticeship as an apothecary and was not a formally trained physician, but he developed a clinical practice for the poor of London, indistinguishable from the role of the present day general practitioner. Observers at the time recognised his concern and compassion and his commitment to treat the whole patient and not just the disease. His enduring contribution was his translation from Latin of the physicians' Pharmacopoeia Londinensis which could be regarded as the first major step towards the demystification of medicine. Culpeper's London Dispensatory and the many other medical treatises that followed were affordable and widely available to the common man. Culpeper antagonised both apothecaries and physicians because he breached the regulations of the day by accepting patients directly. So perhaps Culpeper was, de facto, London's first general practitioner, at least 150 years before the role was formally recognised in the Apothecaries Act 1815.

  17. Veterinary medicines update.

    PubMed

    2017-03-11

    The following information has been produced for Veterinary Record by the Veterinary Medicines Directorate (VMD) to provide an update for veterinary surgeons on recent changes to marketing authorisations for veterinary medicines in the UK and on other relevant issues.

  18. Veterinary medicines: product update.

    PubMed

    2014-04-05

    The following information has been produced for Veterinary Record by the Veterinary Medicines Directorate (VMD) to provide an update for veterinary surgeons on recent changes to marketing authorisations for veterinary medicines in the UK and on other relevant issues.

  19. Veterinary medicines: product update.

    PubMed

    2014-03-01

    The following information has been produced for Veterinary Record by the Veterinary Medicines Directorate (VMD) to provide an update for veterinary surgeons on recent changes to marketing authorisations for veterinary medicines in the UK and on other relevant issues.

  20. Veterinary medicines: product update.

    PubMed

    2014-08-02

    The following information has been produced for Veterinary Record by the Veterinary Medicines Directorate (VMD) to provide an update for veterinary surgeons on recent changes to marketing authorisations for veterinary medicines in the UK and on other relevant issues.

  1. Veterinary medicines: product update.

    PubMed

    2014-11-01

    The following information has been produced for Veterinary Record by the Veterinary Medicines Directorate (VMD) to provide an update for veterinary surgeons on recent changes to marketing authorisations for veterinary medicines in the UK and on other relevant issues.

  2. Veterinary medicines: product update.

    PubMed

    2014-09-06

    The following information has been produced for Veterinary Record by the Veterinary Medicines Directorate (VMD) to provide an update for veterinary surgeons on recent changes to marketing authorisations for veterinary medicines in the UK, and on other relevant issues.

  3. Space in Pentecostal healing practices among Ghanaian migrants in London.

    PubMed

    Krause, Kristine

    2014-01-01

    In this article I analyze different spatial practices related to Pentecostal healing, drawing on fieldwork with Pentecostal believers who have migrated from Ghana to London, UK. I explore the relationship between space and the manifestation of the Holy Spirit by looking at how points of contact with the divine are created in the personal life of people and at the sites where the casting out of demons takes place. Unlike in other spirit-centered healing traditions, the Christian Holy Spirit is not conceived of as embodied in specific places, but rather is spatially unbound. To manifest, however, the Holy Spirit requires specific spatial qualities and esthetics.

  4. London's Tutorial Classes; An Assessment

    ERIC Educational Resources Information Center

    Brook, F. G.

    1970-01-01

    Growth during the 1960s in the number and scope of tutorial classes by the London University Department of Extra-Mural Studies is attributed to considerable help from voluntary personnel, emphasis on written work, and other factors potentially signficant to extension education elsewhere in Britain. (LY)

  5. Commentary: Clinical skills teaching in UK medical education as exemplified by the BM5 curriculum, Faculty of Medicine, University of Southampton

    PubMed Central

    Timm, Anja; Polack, Clare

    2016-01-01

    This commentary seeks to enable comparisons about clinical skills teaching in Germany and the UK. It outlines the British regulatory environment and its impact on programme design. Through the example of the University of Southampton we show how clinical skills teaching is integrated both vertically and horizontally. PMID:27579351

  6. Sport and exercise medicine and the Olympic health legacy

    PubMed Central

    2012-01-01

    London 2012 is the first Olympic and Paralympic Games to explicitly try and develop socioeconomic legacies for which success indicators are specified - the highest profile of which was to deliver a health legacy by getting two million more people more active by 2012. This editorial highlights how specialists in Sport and Exercise Medicine can contribute towards increasing physical activity participation in the UK, as well as how the National Centre for Sport and Exercise Medicine might be a useful vehicle for delivering an Olympic health legacy. Key challenges are also discussed such as acquisition of funding to support new physical activity initiatives, appropriate allocation of resources, and how to assess the impact of legacy initiatives. PMID:22813079

  7. The UK pharmaceutical market. An overview.

    PubMed

    Towse, A

    1996-01-01

    The National Health Service (NHS) accounts for more than 98% of the UK prescription medicines market, which is the sixth largest pharmaceutical market in the world. Most of this market is driven by the UK's approximately 35,000 general practitioners (GPs). It is an open market, with most leading foreign pharmaceutical companies having a strong presence. While the growth rate of this market has been decelerating, it remains one of the fastest growing components of NHS expenditure. The NHS does not operate any kind of national reimbursement list, but the UK government has adopted several means to keep medicines expenditure under control. These include cash incentives and constraints for GPs relating to expenditure on medicines, individual quarterly updates on GP prescribing, the publication of a list of medicines that cannot be prescribed by GPs, the switching of some prescription-only medicines to over-the-counter medicines, and a co-payment system. The main form of economic regulation in the UK, however, remains the Pharmaceutical Price Regulation Scheme (PPRS). This limits the rate-of-return on capital attributable to medicines sales to the NHS, with the intended rate-of-return being equal to that of UK industry overall. The pharmaceutical industry has generally performed relatively well in the UK market, managing to preserve incentives to innovation. This reflects the fact that UK GPs have been able to maintain their clinical freedom, as well as government recognition of the economic contribution made by the pharmaceutical industry. Current issues of interest in the UK pharmaceutical market context include the future of the PPRS, the debates over the imposition of a national formulary and generic substitution, and over parallel trade, the potential impact of managed-care protocols and computer-based prescribing on pharmaceutical expenditures, and possible political changes.

  8. Assessment for Learning and Teacher Learning Communities: UK Teachers' Experiences

    ERIC Educational Resources Information Center

    Hargreaves, Eleanore

    2013-01-01

    In this paper, I explore the experiences of secondary teachers in four London schools [UK] who participated in Teacher Learning Communities, defined as meetings in which professional learning was supported as they learned about Assessment for Learning (AfL). The claim for these communities is that they lead to sustained improvements in teaching…

  9. The London low emission zone baseline study.

    PubMed

    Kelly, Frank; Armstrong, Ben; Atkinson, Richard; Anderson, H Ross; Barratt, Ben; Beevers, Sean; Cook, Derek; Green, Dave; Derwent, Dick; Mudway, Ian; Wilkinson, Paul

    2011-11-01

    roadside monitoring sites was higher than at urban background locations. In the PM10 samples this increased oxidative activity appeared to be associated with increased concentrations of copper (Cu), barium (Ba), and bathophenanthroline disulfonate-mobilized iron (BPS Fe) in the roadside samples. In the PM2.5 samples, no simple association could be seen, suggesting that other unmeasured components were driving the increased oxidative potential in this fraction of the roadside samples. These data suggest that two components were contributing to the oxidative potential of roadside PM, namely Cu and BPS Fe in the coarse fraction of PM (PM with an aerodynamic diameter of 2.5 microm to 10 microm; PM(2.5-10)) and an unidentified redox catalyst in PM2.5. The data derived for this baseline study confirmed key observations from a more limited spatial mapping exercise published in our earlier HEI report on the introduction of the London's Congestion Charging Scheme (CCS) in 2003 (Kelly et al. 2011a,b). In addition, the data set in the current report provided robust baseline information on the oxidative potential and metal content of PM found in the London airshed in the period before implementation of the LEZ; the finding that a proportion of the oxidative potential appears in the PM coarse mode and is apparently related to brake wear raises important issues regarding the nature of traffic management schemes. The final goal of this baseline study was to establish the feasibility, in ethical and operational terms, of using the U.K.'s electronic primary-care records to evaluate the effects of the LEZ on human health outcomes. Data on consultations and prescriptions were compiled from a pilot group of general practices (13 distributed across London, with 100,000 patients; 29 situated in the inner London Borough of Lambeth, with 200,000 patients). Ethics approvals were obtained to link individual primary-care records to modeled NOx concentrations by means of post-codes. (To preserve

  10. Why Research--What Research Should Be Done?: Report of a Collaborative Workshop in the UK to Discuss Social Research Priorities on Visual Impairment

    ERIC Educational Resources Information Center

    Brace, Michael; Herriotts, Paul; Mccullagh, Angela; Nzegwu, Femi

    2007-01-01

    This article reports on a workshop held in London UK in November 2006 to discuss future research priorities in the visual impairment sector in the UK. The workshop was held under the auspices of the VISION 2020 UK Social Research Group, a collaborative group of charitable partners who commission social research in the sector. The broad purpose of…

  11. Modelling of hydrogen infrastructure for vehicle refuelling in London

    NASA Astrophysics Data System (ADS)

    Joffe, D.; Hart, D.; Bauen, A.

    One of the principal barriers to the widespread use of hydrogen as a road transport fuel is the need for a refuelling infrastructure to be established. The lack of an adequate refuelling infrastructure would severely inhibit an uptake of hydrogen vehicles. On the other hand, without significant penetration of these vehicles, the demand for hydrogen would be insufficient to make a widespread conventional refuelling infrastructure economic. The infrastructure is likely to develop initially in cities, due to the high concentration of vehicles and the anticipated air quality benefits of a switch to hydrogen as a road transport fuel. While trial schemes such as the Clean Urban Transport for Europe (CUTE) bus project will establish initial hydrogen refuelling sites, it is not clear how a transition to a widespread refuelling infrastructure will occur. Indeed, the number of possible different ways and scales of producing and distributing hydrogen means that the possible configurations for such an infrastructure are almost endless. Imperial College London is examining transition strategies for a hydrogen infrastructure for vehicle refuelling in London under a project funded by the UK Engineering and Physical Sciences Research Council (EPSRC). Imperial has five project partners from industry and local government to assist in this study: the Greater London Authority (GLA), BP, BOC, BMW and Air Products. This paper presents initial results from technical modelling of hydrogen infrastructure technologies and how they could be deployed to provide an initial facility for the refuelling of hydrogen fuel-cell buses in London. The results suggest that the choice of H 2 production technology can have significant effects on when the infrastructure would be installed, and the timing of hydrogen production, and bus refuelling.

  12. Japan Biotech Forum: London 2010.

    PubMed

    Al-Shamahi, Asma

    2010-11-01

    The Japan Biotech Forum, held in London, included topics covering new licensing developments in the Japanese pharma and biotech industries. This conference report highlights selected presentations on licensing opportunities from several Japanese companies, including CanBas, LivTech, REGiMMUNE, D Western Therapeutics Institute and Chiome Bioscience. Investigational drugs discussed include CBP-501 (CanBas), LIV-2008 (LivTech), RGI-2001 (REGiMMUNE), IVX-214 (D Western Therapeutics Institute/ Nippon Shinyaku) and anti-Sema 3A (Chiome Bioscience).

  13. School Improvement in London: A Global Perspective

    ERIC Educational Resources Information Center

    McAleavy, Tony; Elwick, Alex

    2016-01-01

    This report considers how successful London's schools have been over the past decade and identifies potentially transferable components of the success story. There is much to be learned from the transformation undergone in London that is relevant to policymakers and educationalists worldwide, working in both high-income and low-income countries.…

  14. London's Jewish Communities and State Education

    ERIC Educational Resources Information Center

    Martin, Jane

    2012-01-01

    The Inner London education authority was a notable example of a radical and powerful local government body from which the fight for the comprehensive principle in English secondary education emerged. Building on previous work of women's contribution to state education in London, this articles focuses on Anglo-Jewish educator activists who helped…

  15. Experiences of non-UK-qualified doctors working within the UK regulatory framework: a qualitative study

    PubMed Central

    Slowther, A; Lewando Hundt, GA; Purkis, J; Taylor, R

    2012-01-01

    Objective To explore the experience of non-UK-qualified doctors in working within the regulatory framework of the General Medical Council (GMC) document Good Medical Practice. Design Individual interviews and focus groups. Setting United Kingdom. Participants Non-UK-qualified doctors who had registered with the GMC between 1 April 2006 and 31 March 2008, doctors attending training/induction programmes for non-UK-qualified doctors, and key informants involved in training and support for non-UK-qualified doctors. Main outcome measures Themes identified from analysis of interview and focus group transcripts. Results Information and support for non-UK qualified doctors who apply to register to work in the UK has little reference to the ethical and professional standards required of doctors working in the UK. Recognition of the ethical, legal and cultural context of UK healthcare occurs once doctors are working in practice. Non-UK qualified doctors reported clear differences in the ethical and legal framework for practising medicine between the UK and their country of qualification, particularly in the model of the doctor–patient relationship. The degree of support for non-UK-qualified doctors in dealing with ethical concerns is related to the type of post they work in. European doctors describe similar difficulties with working in an unfamiliar regulatory framework to their non-European colleagues. Conclusions Non-UK-qualified doctors experience a number of difficulties related to practising within a different ethical and professional regulatory framework. Provision of information and educational resources before registration, together with in-practice support would help to develop a more effective understanding of GMP and its implications for practice in the UK. PMID:22408082

  16. Attitudes to and knowledge about elderly people: a comparative analysis of students of medicine, English and Computer Science and their teachers.

    PubMed

    Edwards, M J; Aldous, I R

    1996-05-01

    Attitudes to and knowledge about elderly people were assessed in 1091 students and lecturers from the London Hospital Medical College (LHMC), London, UK and the English and Computer Science departments of Queen Mary and Westfield College (QMW), London, UK. General knowledge about elderly people was measured by the Palmore 'Facts about Aging Quiz 1'. Attitudes towards elderly people were measured by the Rosencranz and McNevin Semantic Differential scale. A higher level of knowledge about elderly people was found both in medical students and in medical lecturers compared to their counterparts in the English and Computer Science departments (P < 0.001). The cross-sectional data indicated that medical students developed a significantly increasing knowledge about elderly people as they progressed through their training, in contrast to students of English and Computer Science. Scores on the Rosencranz & McNevin scale indicated that attitudes towards elderly people across all three groups of students and lecturers were similar. The scores obtained for all groups indicated that they held approximately neutral attitudes towards elderly people. A significant correlation (P < 0.001) was found between high levels of knowledge about elderly people, and positive attitudes towards them. The necessity of interventions to improve general attitudes towards and knowledge of elderly people among medical students is questioned. It is suggested that future research should look beyond surveys of general attitudes towards elderly people for the causes of the current lack of interest in geriatric medicine.

  17. Comparability: manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015.

    PubMed

    Williams, David J; Archer, Richard; Archibald, Peter; Bantounas, Ioannis; Baptista, Ricardo; Barker, Roger; Barry, Jacqueline; Bietrix, Florence; Blair, Nicholas; Braybrook, Julian; Campbell, Jonathan; Canham, Maurice; Chandra, Amit; Foldes, Gabor; Gilmanshin, Rudy; Girard, Mathilde; Gorjup, Erwin; Hewitt, Zöe; Hourd, Paul; Hyllner, Johan; Jesson, Helen; Kee, Jasmin; Kerby, Julie; Kotsopoulou, Nina; Kowalski, Stanley; Leidel, Chris; Marshall, Damian; Masi, Louis; McCall, Mark; McCann, Conor; Medcalf, Nicholas; Moore, Harry; Ozawa, Hiroki; Pan, David; Parmar, Malin; Plant, Anne L; Reinwald, Yvonne; Sebastian, Sujith; Stacey, Glyn; Thomas, Robert J; Thomas, Dave; Thurman-Newell, Jamie; Turner, Marc; Vitillo, Loriana; Wall, Ivan; Wilson, Alison; Wolfrum, Jacqueline; Yang, Ying; Zimmerman, Heiko

    2016-07-01

    This paper summarizes the proceedings of a workshop held at Trinity Hall, Cambridge to discuss comparability and includes additional information and references to related information added subsequently to the workshop. Comparability is the need to demonstrate equivalence of product after a process change; a recent publication states that this 'may be difficult for cell-based medicinal products'. Therefore a well-managed change process is required which needs access to good science and regulatory advice and developers are encouraged to seek help early. The workshop shared current thinking and best practice and allowed the definition of key research questions. The intent of this report is to summarize the key issues and the consensus reached on each of these by the expert delegates.

  18. Heavens Open Up for UK Astronomers

    NASA Astrophysics Data System (ADS)

    2002-07-01

    A significant milestone for British and European science occurred today (July 8, 2002) when the Council of the European Southern Observatory (ESO) met in London. At this historical meeting, the United Kingdom was formally welcomed into ESO by the nine other member states. The UK, one of the leading nations in astronomical research, now joins one of the world's major astronomical organisations. UK astronomers will now be able to use the four 8.2-metre and several 1.8-metre telescopes that comprise the Very Large Telescope (VLT) facility located at the Paranal Observatory in the northern part of the Atacama desert in Chile, as well as two 4-m class telescopes and several smaller ones at the ESO La Silla Observatory further south. The UK will also benefit from increased involvement in the design and construction of the Atacama Large Millimetre Array (ALMA), a network of 64 twelve-metre telescopes also sited in Chile, and play a defining role in ESO's 100-metre Overwhelmingly Large Telescope (OWL). Sir Martin Rees , The Astronomer Royal, said, "Joining ESO is good for UK science, and I think good for Europe as well. It offers us access to the VLT's 8-m class telescopes and restores the UK's full competitiveness in optical astronomy. We're now guaranteed full involvement in ALMA and in the next generation of giant optical instruments - projects that will be at the forefront of the research in the next decade and beyond. Moreover, our commitment to ESO should enhance its chances of forging ahead of the US in these technically challenging and high profile scientific projects. UK membership of ESO is a significant and welcome outcome of this government's increasing investment in science". Prof. Ian Halliday , Chief Executive of the Particle Physics and Astronomy Research Council (PPARC), the UK's strategic science investment agency said, "The United Kingdom already participates in Europe's flagship particle physics research and the space science research programmes through

  19. An RAS Specialist Meeting, London, 14 October 2005: "Science from La Palma - Looking Beyond 2009"

    NASA Astrophysics Data System (ADS)

    Lennon, D.; Evans, C.; Drew, J.

    2005-12-01

    In 2009 the international agreement setting up the Roque de los Muchachos Observatory on the island of La Palma will have been in existence for a period of 30 years. In 2007 the United Kingdom will have to make a decision on whether or not to withdraw from that agreement and PPARC, through its ownership of the Isaac Newton Group of Telescopes, has the responsibility of deciding on the UK's involvement in the observatory beyond 2009. As part of the decision making process, and in support of the UK's overall strategic re-evaluation in astronomy, the ING was reviewed during 2005. It was therefore thought timely to assess recent scientific achievements from the Roque de los Muchachos, and to consider what role the observatory might have beyond 2009. Under the auspices of the Royal Astronomical Society a Specialist Meeting was held in Burlington House, Piccadilly, London on October 14th 2005 and was attended by approximately 100 astronomers from around the UK.

  20. Geological Society of London Issues Statement on Climate Change

    NASA Astrophysics Data System (ADS)

    Summerhayes, Colin

    2011-02-01

    On 1 November the Geological Society of London (GSL) published a statement (http://www.geolsoc.org.uk/gsl/site//GSL//lang/en/climatechange) about the geological evidence relating to past climates, atmospheric carbon levels, and their interrelationships. The online version also carries a list of recommendations for further reading. The GSL's Geoscientist magazine (http://www.geolsoc.org.uk/gsl/site/GSL/lang/en/page8578.html) reported Bryan Lovell, GSL president, as saying, “Climate change is a defining issue of our time, whose full understanding needs geology's long perspective. Earth scientists can read…the geological record of changes in climate that occurred long before we were around to light so much as a camp fire, let alone burn coal, gas and oil. A dramatic global warming event 55 million years ago gives us a particularly clear indication of what happens when there is a sudden release of 1500 billion tonnes of carbon into Earth's atmosphere. It gets hot, the seas become more acid, and there is widespread extinction of life. We are a third of the way to repeating that ancient natural input of carbon through our own agency. The message from the rocks is that it would be a good idea to stop pulling that carbon trigger.”

  1. Cord blood banking in London: the first 1000 collections.

    PubMed

    Armitage, S; Warwick, R; Fehily, D; Navarrete, C; Contreras, M

    1999-07-01

    The London Cord Blood Bank was established with the aim of collecting, processing and storing 10000 unrelated stem cell donations for the significant number of children in the UK requiring transplantation, for whom a matched unrelated bone marrow donor cannot be found. Collection is performed at two hospitals by dedicated cord blood bank staff after delivery of the placenta. Mothers are interviewed regarding medical, ethnic and behavioural history by nurse counsellors and sign a detailed consent form. Donations are returned to the bank for processing. Volume reduction is undertaken by a simple, closed, semi-automated blood processing system, with excellent recovery of progenitor cells. Units are cryopreserved and stored in the vapour phase of liquid nitrogen. Blood samples from mothers and cord blood donations are tested for the UK mandatory red cell and microbiology markers for blood donors. Donations are typed for HLA-A, B and DR at medium resolution (antigen split) level using sequence-specific oligonucleotide probing and sequence-specific priming techniques. The selection of collection hospitals on the basis of ethnic mix has proven effective, with 41.5% of donations derived from non-European caucasoid donors. Bacterial contamination of collections has been dramatically reduced by implementation of improved umbilical cord decontamination protocols.

  2. The Tower of London bomb explosion.

    PubMed Central

    Tucker, K; Lettin, A

    1975-01-01

    After the detonation of a bomb in the Tower of London 37 people were brought to St. Bartholomew's Hospital. The explosion caused numerous severe injuries of a type rarely seen in peacetime. PMID:1148778

  3. London Dispersion Forces and "The Wave"

    NASA Astrophysics Data System (ADS)

    Wilcox, C. Jayne

    1998-10-01

    An analogy is presented likening London dispersion forces to "The Wave", a popular ritual performed by fans attending sports events in large stadia. Similarities between people in the stands and electrons in atoms are emphasized.

  4. Perceived causes of differential attainment in UK postgraduate medical training: a national qualitative study

    PubMed Central

    Viney, Rowena; Needleman, Sarah; Griffin, Ann

    2016-01-01

    Objectives Explore trainee doctors’ experiences of postgraduate training and perceptions of fairness in relation to ethnicity and country of primary medical qualification. Design Qualitative semistructured focus group and interview study. Setting Postgraduate training in England (London, Yorkshire and Humber, Kent Surrey and Sussex) and Wales. Participants 137 participants (96 trainees, 41 trainers) were purposively sampled from a framework comprising: doctors from all stages of training in general practice, medicine, obstetrics and gynaecology, psychiatry, radiology, surgery or foundation, in 4 geographical areas, from white and black and minority ethnic (BME) backgrounds, who qualified in the UK and abroad. Results Most trainees described difficult experiences, but BME UK graduates (UKGs) and international medical graduates (IMGs) could face additional difficulties that affected their learning and performance. Relationships with senior doctors were crucial to learning but bias was perceived to make these relationships more problematic for BME UKGs and IMGs. IMGs also had to deal with cultural differences and lack of trust from seniors, often looking to IMG peers for support instead. Workplace-based assessment and recruitment were considered vulnerable to bias whereas examinations were typically considered more rigorous. In a system where success in recruitment and assessments determines where in the country you can get a job, and where work–life balance is often poor, UK BME and international graduates in our sample were more likely to face separation from family and support outside of work, and reported more stress, anxiety or burnout that hindered their learning and performance. A culture in which difficulties are a sign of weakness made seeking support and additional training stigmatising. Conclusions BME UKGs and IMGs can face additional difficulties in training which may impede learning and performance. Non-stigmatising interventions should focus on

  5. Integrated Cancer System: a perspective on developing an integrated system for cancer services in London

    PubMed Central

    Haire, K; Burton, C; Park, R; Reynolds, J; Stewart, D

    2012-01-01

    This article explores the potential for integrated cancer systems to improve the quality of care and deliver cost efficiencies and improve outcomes for cancer patients. Currently, patients in the UK still have poorer survival rates than comparable countries such as Canada, Sweden, Norway and Australia. Improving the quality of cancer services is a key policy objective and cancer is a priority outcome measure in both the NHS and Public Health Outcomes Framework. Evidence suggests that better integrated delivery has the potential to improve the quality and reduce the cost of healthcare, and ultimately improve health outcomes. One of the key themes from the Model of Care for Cancer Services1 was that cancer services should be commissioned along pathways and that provider networks should be established to deliver care. London has two integrated cancer systems; one covering north central and east London (London Cancer) and the other covering west and south London (London Cancer Alliance). There a number of areas in cancer care that the current model of service provision has failed to adequately address and which have the potential to improve significantly though implementation of integrated services. These include improving early diagnosis, reducing inequalities in access to treatment and outcomes and maximising research and training across the system. Important drivers for the integration of cancer services are strong clinical leadership, shared informatics systems, focusing on quality of services and improving patient experience. Emerging needs of integrated cancer in London are around strengthening the involvement of primary care, public health and the third sector; working to develop sufficient capacity and expertise in primary care and collaborating more closely with commissioners to develop integrated systems. PMID:25949664

  6. Spatially resolved flux measurements of NOx from London suggest significantly higher emissions than predicted by inventories.

    PubMed

    Vaughan, Adam R; Lee, James D; Misztal, Pawel K; Metzger, Stefan; Shaw, Marvin D; Lewis, Alastair C; Purvis, Ruth M; Carslaw, David C; Goldstein, Allen H; Hewitt, C Nicholas; Davison, Brian; Beevers, Sean D; Karl, Thomas G

    2016-07-18

    To date, direct validation of city-wide emissions inventories for air pollutants has been difficult or impossible. However, recent technological innovations now allow direct measurement of pollutant fluxes from cities, for comparison with emissions inventories, which are themselves commonly used for prediction of current and future air quality and to help guide abatement strategies. Fluxes of NOx were measured using the eddy-covariance technique from an aircraft flying at low altitude over London. The highest fluxes were observed over central London, with lower fluxes measured in suburban areas. A footprint model was used to estimate the spatial area from which the measured emissions occurred. This allowed comparison of the flux measurements to the UK's National Atmospheric Emissions Inventory (NAEI) for NOx, with scaling factors used to account for the actual time of day, day of week and month of year of the measurement. The comparison suggests significant underestimation of NOx emissions in London by the NAEI, mainly due to its under-representation of real world road traffic emissions. A comparison was also carried out with an enhanced version of the inventory using real world driving emission factors and road measurement data taken from the London Atmospheric Emissions Inventory (LAEI). The measurement to inventory agreement was substantially improved using the enhanced version, showing the importance of fully accounting for road traffic, which is the dominant NOx emission source in London. In central London there was still an underestimation by the inventory of 30-40% compared with flux measurements, suggesting significant improvements are still required in the NOx emissions inventory.

  7. 12. Photo copy of drawing, May 21, 1963. NEW LONDON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Photo copy of drawing, May 21, 1963. NEW LONDON LEDGE LIGHT STATION LIGHTING. Drawing no. 03-2730, U.S. Coast Guard Civil Engineering Unit, Warwick, Rhode Island. - New London Ledge Lighthouse, Long Island Sound, East of main harbor channel, New London, New London County, CT

  8. How To: Preparing to Find a Job as a Spanish Teacher in the UK

    ERIC Educational Resources Information Center

    Talero, Gemma Carmen Belmonte

    2016-01-01

    This case study is about the design of the one-day course "How to find a job as a Spanish teacher in the UK," which is taught at the Instituto Cervantes in London. The course came to exist due to a large number of requests from Spaniards who have come to the UK in recent years--many of them wanting to find a job as a Spanish teacher--and…

  9. Proceedings of the Seventh International Conference on Educational Data Mining (EDM) (7th, London, United Kingdom, July 4-7, 2014)

    ERIC Educational Resources Information Center

    Stamper, John, Ed.; Pardos, Zachary, Ed.; Mavrikis, Manolis, Ed.; McLaren, Bruce M., Ed.

    2014-01-01

    The 7th International Conference on Education Data Mining held on July 4th-7th, 2014, at the Institute of Education, London, UK is the leading international forum for high-quality research that mines large data sets in order to answer educational research questions that shed light on the learning process. These data sets may come from the traces…

  10. Women from Africa living with HIV in London: a descriptive study.

    PubMed

    Anderson, J; Doyal, L

    2004-01-01

    There are no studies that have examined the particular needs and experiences of African women living with HIV in the UK at a time when they represent an increasingly large proportion of the UK HIV epidemic. This study explores the illness biographies and daily lives of HIV-positive African women receiving treatment in London. Sixty-two women from 11 African countries attending HIV specialist clinics in five London hospitals participated in self-completion questionnaires and in depth semi-structured interviews. Using a narrative approach, women were asked to talk about their HIV status in the broader context of their life history. Important differences exist within this group based mainly on nationality, income, education level and legal status in the UK. However, marked similarities also emerged which were related in part to their situation as migrants and were compounded by their illness. Stigma, both actual and perceived, had a profound impact on women's lives, making control of information about their situation a matter of acute concern. This had an effect on how women accessed health services and voluntary sector agencies. The resilience of women in dealing with difficulties in their lives was strengthened by religious belief. Such similarities and differences need to be properly understood by health and social care professionals if they are to offer the most appropriate care for this growing population of patients.

  11. Supporting a UK Success Story: The Impact of University Research and Sport Development

    ERIC Educational Resources Information Center

    Universities UK, 2012

    2012-01-01

    As part of an Olympic and Paralympic themed Universities Week this new report highlights just some of the many ways in which research will help Team Great Britain achieve exceptional results. While most attention will be on the results achieved in London this summer, it is inspiring to look at the research taking place in UK universities that will…

  12. Multiple large clusters of tuberculosis in London: a cross-sectional analysis of molecular and spatial data.

    PubMed

    Smith, Catherine M; Maguire, Helen; Anderson, Charlotte; Macdonald, Neil; Hayward, Andrew C

    2017-01-01

    Large outbreaks of tuberculosis (TB) represent a particular threat to disease control because they reflect multiple instances of active transmission. The extent to which long chains of transmission contribute to high TB incidence in London is unknown. We aimed to estimate the contribution of large clusters to the burden of TB in London and identify risk factors. We identified TB patients resident in London notified between 2010 and 2014, and used 24-locus mycobacterial interspersed repetitive units-variable number tandem repeat strain typing data to classify cases according to molecular cluster size. We used spatial scan statistics to test for spatial clustering and analysed risk factors through multinomial logistic regression. TB isolates from 7458 patients were included in the analysis. There were 20 large molecular clusters (with n>20 cases), comprising 795 (11%) of all cases; 18 (90%) large clusters exhibited significant spatial clustering. Cases in large clusters were more likely to be UK born (adjusted odds ratio 2.93, 95% CI 2.28-3.77), of black-Caribbean ethnicity (adjusted odds ratio 3.64, 95% CI 2.23-5.94) and have multiple social risk factors (adjusted odds ratio 3.75, 95% CI 1.96-7.16). Large clusters of cases contribute substantially to the burden of TB in London. Targeting interventions such as screening in deprived areas and social risk groups, including those of black ethnicities and born in the UK, should be a priority for reducing transmission.

  13. Multiple large clusters of tuberculosis in London: a cross-sectional analysis of molecular and spatial data

    PubMed Central

    Maguire, Helen; Anderson, Charlotte; Macdonald, Neil; Hayward, Andrew C.

    2017-01-01

    Large outbreaks of tuberculosis (TB) represent a particular threat to disease control because they reflect multiple instances of active transmission. The extent to which long chains of transmission contribute to high TB incidence in London is unknown. We aimed to estimate the contribution of large clusters to the burden of TB in London and identify risk factors. We identified TB patients resident in London notified between 2010 and 2014, and used 24-locus mycobacterial interspersed repetitive units–variable number tandem repeat strain typing data to classify cases according to molecular cluster size. We used spatial scan statistics to test for spatial clustering and analysed risk factors through multinomial logistic regression. TB isolates from 7458 patients were included in the analysis. There were 20 large molecular clusters (with n>20 cases), comprising 795 (11%) of all cases; 18 (90%) large clusters exhibited significant spatial clustering. Cases in large clusters were more likely to be UK born (adjusted odds ratio 2.93, 95% CI 2.28–3.77), of black-Caribbean ethnicity (adjusted odds ratio 3.64, 95% CI 2.23–5.94) and have multiple social risk factors (adjusted odds ratio 3.75, 95% CI 1.96–7.16). Large clusters of cases contribute substantially to the burden of TB in London. Targeting interventions such as screening in deprived areas and social risk groups, including those of black ethnicities and born in the UK, should be a priority for reducing transmission. PMID:28149918

  14. Health Technology Assessment in the UK.

    PubMed

    Raftery, James; Powell, John

    2013-10-12

    In this Review, we discuss the UK's Health Technology Assessment programme, which is 20 years old in 2013. We situate the programme in the context of the UK landscape for evidence-based medicine, including in relation to the National Institute for Health and Care Excellence and as guidance to the National Health Service. We identify features that might be of value to other health systems as they confront the challenges of rapid innovation and rising costs. We use examples of recent studies to show the strengths and weaknesses of the programme.

  15. Suicide on the London Underground System.

    PubMed

    Farmer, R; O'Donnell, I; Tranah, T

    1991-09-01

    Over the past 50 years there has been an increase in the numbers of people jumping/falling in front of trains on the London Underground system. Case-fatality rates have fallen from 70% in the 1950s to 55% today. The proportion certified as suicide has fallen while the proportions certified as accidents or open verdicts have risen. There is unusual clustering of events at some stations which are adjacent to psychiatric units. The hypothesis that ease of access to London Underground stations may sometimes be a determinant of suicide is investigated.

  16. Survey of community pharmacists' perception of electronic cigarettes in London

    PubMed Central

    Marques Gomes, Ana C N; Nabhani-Gebara, Shereen; Kayyali, Reem; Buonocore, Federico; Calabrese, Gianpiero

    2016-01-01

    Objectives To seek community pharmacists' perception on use, safety and possible effectiveness of e-cigarettes as quit smoking tools, and their future regulation. Setting A survey of a sample of 154 community pharmacies across London, UK. Context E-cigarettes have exclusively established themselves in the market through consumers-led demand. To date, e-cigarettes still remain unregulated and can be easily purchased in shops, over the internet, but more controversially also in pharmacies in the UK. Pharmacists find themselves with a shortage of information on their safety and efficacy, and may experience an ethical dilemma when consulted by patients/customers. Key findings Response rate: 60% (n=92). Independent pharmacies accounted for 90% of the sample. The majority of participants (73%) sell e-cigarettes. A minority of participants (20%) have been presented with adverse effects such as cough and dry mouth. As possible reasons for their use, pharmacists ranked ‘aid in stop smoking’ as the most important (56%), with ‘cheaper alternative’ (43%) and ‘social/recreational use’ (31%) being the least important ones. Safety issues were raised as statements such as ‘e-liquid in cartridges may be toxic’ were agreed by 52% of respondents. The majority of pharmacists (97%) were supportive of e-cigarettes being regulated, expressing current concerns regarding excipients (42%) and nicotine content (34%). Participants indicated that they would require training in the form of information packs (88%), online tutorials (67%), continuous professional development (CPD) workshops (43%) to cover safety, counselling, dosage instructions, adverse effects and role in the smoking cessation care pathway in the future. Conclusions Pharmacists expressed concerns about the safety of e-cigarettes, especially regarding the amounts of excipients and nicotine as these still remain unregulated. Currently, there are no guidelines for pharmacists regarding e-cigarettes. Community

  17. Jack London and the San Francisco earthquake

    USGS Publications Warehouse

    Sachs, J.S.

    1982-01-01

    After it was over, it seemed to many, and especially to eyewitnesses like Jack London, that the earthquake and fire had devastated San Francisco. However people were confident that, like the phoeniz, San Francisco would rise from the ashes and regain her palce as the "Imperial City of the West." 

  18. Knives and Other Weapons in London Schools

    ERIC Educational Resources Information Center

    Neill, S. R. St. J.

    2005-01-01

    London schools operate in an area where crime rates, including violent crime, is statistically more frequent than the average for the whole of England and Wales (Moore and Yeo 2004). Violent crime in the capital increased (though not to a statistically significant extent) between 2002/3 and 2003/4 (Moore and Yeo 2004b). This has led to a…

  19. Preventing suicide on the London Underground.

    PubMed

    Clarke, R V; Poyner, B

    1994-02-01

    A field study was carried out to investigate the possibility of preventing suicide on the London Underground. Four groups of potentially valuable measures were identified with the objectives of: (i) reducing public access to the tracks; (ii) improving surveillance by station staff; (iii) facilitating emergency stops; and (iv) reducing injury. These strategies are discussed.

  20. Movement and Character. Lecture, London, 1946

    ERIC Educational Resources Information Center

    Montesorri, Maria

    2013-01-01

    Dr. Montessori's words from the 1946 London Lectures describe principles of intelligence and character, the work of the hand, and movement with a purpose as being integral to self-construction. The perfection of movement is spiritual, says Dr. Montessori. Repetition of practical life exercises are exercises in movement with the dignity of human…

  1. UK malaria treatment guidelines.

    PubMed

    Lalloo, David G; Shingadia, Delane; Pasvol, Geoffrey; Chiodini, Peter L; Whitty, Christopher J; Beeching, Nicholas J; Hill, David R; Warrell, David A; Bannister, Barbara A

    2007-02-01

    ); quinine is highly effective but poorly tolerated in prolonged dosage and is always supplemented by additional treatment, usually with oral doxycycline. ALL patients treated for P. falciparum malaria should be admitted to hospital for at least 24 h, since patients can deteriorate suddenly, especially early in the course of treatment. Severe falciparum malaria, or infections complicated by a relatively high parasite count (more than 2% of red blood cells parasitized), should be treated with intravenous therapy until the patient is well enough to continue with oral treatment. In the UK, the treatment of choice for severe or complicated malaria is currently an infusion of intravenous quinine. This may exacerbate hypoglycaemia that can occur in malaria; patients treated with intravenous quinine therefore require careful monitoring. Intravenous artesunate reduces high parasite loads more rapidly than quinine and is more effective in treating severe malaria in selected situations. It can also be used in patients with contra-indications to quinine. Intravenous artesunate is unlicensed in the EU. Assistance in obtaining artesunate may be sought from specialist tropical medicine centres, on consultation, for named patients. Patients with severe or complicated malaria should be managed in a high dependency or intensive care environment. They may require haemodynamic support and management of acute respiratory distress syndrome, disseminated intravascular coagulation, renal impairment/failure, seizures, and severe intercurrent infections including gram-negative bacteraemia/septicaemia. Falciparum malaria in pregnancy is more likely to be severe and complicated: the placenta contains high levels of parasites. Stillbirth or early delivery may occur and diagnosis can be difficult if parasites are concentrated in the placenta and scanty in the blood. The treatment of choice for falciparum malaria in pregnancy is quinine; doxycycline is contraindicated in pregnancy but clindamycin can be

  2. Two Years on: Koha 3.0 in Use at the CAMLIS Library, Royal London Homoeopathic Hospital

    ERIC Educational Resources Information Center

    Bissels, Gerhard; Chandler, Andrea

    2010-01-01

    Purpose: The purpose of this paper is to describe the further development of the Koha 3.0 library management system (LMS) and the involvement of external software consultants at the Complementary and Alternative Medicine Library and Information Service (CAMLIS), Royal London Homoeopathic Hospital. Design/methodology/approach: The paper takes the…

  3. Implementation of an Open Source Library Management System: Experiences with Koha 3.0 at the Royal London Homoeopathic Hospital

    ERIC Educational Resources Information Center

    Bissels, Gerhard

    2008-01-01

    Purpose: The purpose of this paper is to describe the selection process and criteria that led to the implementation of the Koha 3.0 library management system (LMS) at the Complementary and Alternative Medicine Library and Information Service (CAMLIS), Royal London Homoeopathic Hospital. Design/methodology/approach: The paper is a report based on…

  4. Increasing Plasmodium falciparum malaria in southwest London: a 25 year observational study

    PubMed Central

    Williams, J; Chitre, M; Sharland, M

    2002-01-01

    Aims: To identify changes in the presenting number and species of imported malaria in children in southwest London. Methods: A prospective single observer study over 25 years (1975–99) of all cases of paediatric malaria seen at St George's Hospital. Results: A confirmed diagnosis was made in 249 children (56% boys; 44% girls; median age 8.0 years). Of these, 53% were UK residents and 44% were children travelling to the UK. A significant increase was noted in the number of cases over the 25 years (1975–79: mean 4.8 cases/year; 1990–99: mean 13.7 cases/year). Over the 25 years Plasmodium falciparum was seen in 77%, P vivax in 14%, P ovale in 6%, and P malariae in 3% of cases. P falciparum had increased in frequency (1975–79: P falciparum 50%, P vivax 50%; 1990–99: P falciparum 82%, P vivax 6%), associated with an increase in the proportion of children acquiring their infection in sub-Saharan Africa. Median time between arrival in the UK to the onset of fever was: P falciparum, 5 days; P ovale, 25 days; P malariae, 37 days; and P vivax, 62 days. Median time interval between the onset of fever to commencement of treatment was 4 days. This had not improved over the 25 year period. Only 41% of UK resident children presenting to hospital had taken prophylaxis and the overall number of symptomatic children taking no prophylaxis was increasing. Conclusion: Imported childhood P falciparum malaria is increasing in southwest London associated with increasing travel from sub-Saharan Africa. Over the 25 year period there has been no improvement in chemoprophylaxis rates or time to diagnosis. PMID:12023177

  5. External and internal noise surveys of London primary schools.

    PubMed

    Shield, Bridget; Dockrell, Julie E

    2004-02-01

    Internal and external noise surveys have been carried out around schools in London, UK, to provide information on typical levels and sources to which children are exposed while at school. Noise levels were measured outside 142 schools, in areas away from flight paths into major airports. Here 86% of the schools surveyed were exposed to noise from road traffic, the average external noise level outside a school being 57 dB L(Aeq). Detailed internal noise surveys have been carried out in 140 classrooms in 16 schools, together with classroom observations. It was found that noise levels inside classrooms depend upon the activities in which the children are engaged, with a difference of 20 dB L(Aeq) between the "quietest" and "noisiest" activities. The average background noise level in classrooms exceeds the level recommended in current standards. The number of children in the classroom was found to affect noise levels. External noise influenced internal noise levels only when children were engaged in the quietest classroom activities. The effects of the age of the school buildings and types of window upon internal noise were examined but results were inconclusive.

  6. Air earth current measurements at Kew, London, 1909 1979

    NASA Astrophysics Data System (ADS)

    Harrison, R. G.; Ingram, W. J.

    2005-07-01

    A vertical conduction current arises from the global ionospheric potential and the integrated electrical resistance between the Earth's surface and the ionosphere. The conduction current density varies with the ionospheric potential and the vertical (columnar) resistance. At the surface, the conduction current density is known as the air-earth current. C.T.R. Wilson developed a measurement technique for the air-earth current in 1906, which was implemented by the British Meteorological Office at its Kew Observatory (51° 28'N, 0° 19'W) near London in 1909. Simultaneous measurements of air-earth current, potential gradient and positive air conductivity were made almost continuously until 1979 using the Wilson method on fine afternoons. A summary of the complete set of monthly mean measurements is presented here for the first time. The data span the nuclear weapons testing period and the UK Clean Air Act of 1956, both of which influenced the measurements obtained. Annual average values of the air earth current density at Kew are 0.97 pA·m -2 (1909-1931), 1.04 pA·m -2 (1932-1949) and 1.41 pA·m -2 (1967-1979).

  7. 32. VIEW OF PHOTO CAPTIONED 'SUBMARINE BASE, NEW LONDON, CONN. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. VIEW OF PHOTO CAPTIONED 'SUBMARINE BASE, NEW LONDON, CONN. OCTOBER 3, 1932. COMPLETION OF ERECTION OF STEELWORK FOR ELEVATOR. LOOKING NORTH. CONTRACT NO. Y-1539-ELEVATOR, SUBMARINE ESCAPE TANK.' - U.S. Naval Submarine Base, New London Submarine Escape Training Tank, Albacore & Darter Roads, Groton, New London County, CT

  8. 30. VIEW OF PHOTO CAPTIONED 'SUBMARINE BASE, NEW LONDON, CONNECTICUT. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. VIEW OF PHOTO CAPTIONED 'SUBMARINE BASE, NEW LONDON, CONNECTICUT. 2 JUNE 1930. SUBMARINE TRAINING TANK - STEELWORK 98% COMPLETE; BRICKWORK 95% COMPLETE, PIPING 10% IN PLACE. LOOKING NORTH. CONTRACT NO. Y-1539-ELEVATOR, SUBMARINE ESCAPE TANK.' - U.S. Naval Submarine Base, New London Submarine Escape Training Tank, Albacore & Darter Roads, Groton, New London County, CT

  9. The role of one large greenspace in mitigating London's nocturnal urban heat island.

    PubMed

    Doick, Kieron J; Peace, Andrew; Hutchings, Tony R

    2014-09-15

    The term urban heat island (UHI) describes a phenomenon where cities are on average warmer than the surrounding rural area. Trees and greenspaces are recognised for their strong potential to regulate urban air temperatures and combat the UHI. Empirical data is required in the UK to inform predictions on cooling by urban greenspaces and guide planning to maximise cooling of urban populations. We describe a 5-month study to measure the temperature profile of one of central London's large greenspaces and also in an adjacent street to determine the extent to which the greenspace reduced night-time UHI intensity. Statistical modelling displayed an exponential decay in the extent of cooling with increased distance from the greenspace. The extent of cooling ranged from an estimated 20 m on some nights to 440 m on other nights. The mean temperature reduction over these distances was 1.1 °C in the summer months, with a maximum of 4 °C cooling observed on some nights. Results suggest that calculation of London's UHI using Met Stations close to urban greenspace can underestimate 'urban' heat island intensity due to the cooling effect of the greenspace and values could be in the region of 45% higher. Our results lend support to claims that urban greenspace is an important component of UHI mitigation strategies. Lack of certainty over the variables that govern the extent of the greenspace cooling influence indicates that the multifaceted roles of trees and greenspaces in the UK's urban environment merit further consideration.

  10. An outbreak of illness among schoolchildren in London: toxic poisoning not mass hysteria.

    PubMed Central

    Aldous, J C; Ellam, G A; Murray, V; Pike, G

    1994-01-01

    STUDY OBJECTIVE--To determine the cause of an outbreak of acute gastrointestinal illness that occurred shortly after lunch in children attending a school in London, UK. DESIGN--A questionnaire survey of children at the affected school was carried out on the day after the incident. Microbiological, environmental, and toxicological investigations were also undertaken. SETTING--A school in London, UK. PARTICIPANTS--Altogether 374/468 (80%) of the children who had eaten lunch at the school on the day of the incident completed a questionnaire. MAIN RESULTS--There was a significant association between illness and the consumption of raw cucumber (relative risk = 6.1; 95% confidence interval 2.2, 16). Microbiological investigation of the foods served at lunch did not show any pathogens and toxicological investigations suggested that the cucumbers were contaminated by a pesticide. CONCLUSIONS--Although the outbreak displayed several typical features of mass psychogenic illness, the most probable cause was a toxic chemical present in cucumber served at lunch. Those responsible for investigating outbreaks of illness should be aware of the possible toxicological causes and the appropriate modes of investigation. They should be wary of too readily attributing a psychogenic cause to unusual outbreaks of acute illness in schoolchildren. PMID:8138768

  11. Wittgenstein, medicine and neuropsychiatry.

    PubMed

    Teive, Hélio A G; Silva, Guilherme Ghizoni; Munhoz, Renato P

    2011-08-01

    A historical review is presented of the link between Ludwig Wittgenstein, considered the most important philosopher of the 20th century, and medicine, particularly neurology and psychiatry. Wittgenstein worked as a porter at Guy's Hospital in London, and then as a technician at the Royal Victoria Infirmary in Newcastle. He wrote about his important insights into language, and neuroscience. It has been suggested that he had Asperger syndrome and a possible movement disorder (mannerisms).

  12. Pathways, Networks and Systems Medicine Conferences

    SciTech Connect

    Nadeau, Joseph H.

    2013-11-25

    The 6th Pathways, Networks and Systems Medicine Conference was held at the Minoa Palace Conference Center, Chania, Crete, Greece (16-21 June 2008). The Organizing Committee was composed of Joe Nadeau (CWRU, Cleveland), Rudi Balling (German Research Centre, Brauschweig), David Galas (Institute for Systems Biology, Seattle), Lee Hood (Institute for Systems Biology, Seattle), Diane Isonaka (Seattle), Fotis Kafatos (Imperial College, London), John Lambris (Univ. Pennsylvania, Philadelphia),Harris Lewin (Univ. of Indiana, Urbana-Champaign), Edison Liu (Genome Institute of Singapore, Singapore), and Shankar Subramaniam (Univ. California, San Diego). A total of 101 individuals from 21 countries participated in the conference: USA (48), Canada (5), France (5), Austria (4), Germany (3), Italy (3), UK (3), Greece (2), New Zealand (2), Singapore (2), Argentina (1), Australia (1), Cuba (1), Denmark (1), Japan (1), Mexico (1), Netherlands (1), Spain (1), Sweden (1), Switzerland (1). With respect to speakers, 29 were established faculty members and 13 were graduate students or postdoctoral fellows. With respect to gender representation, among speakers, 13 were female and 28 were male, and among all participants 43 were female and 58 were male. Program these included the following topics: Cancer Pathways and Networks (Day 1), Metabolic Disease Networks (Day 2), Day 3 ? Organs, Pathways and Stem Cells (Day 3), and Day 4 ? Inflammation, Immunity, Microbes and the Environment (Day 4). Proceedings of the Conference were not published.

  13. Mortality and temperature in Sofia and London

    PubMed Central

    Pattenden, S; Nikiforov, B; Armstrong, B

    2003-01-01

    Study objective: Heat and cold have been associated with increased mortality, independently of seasonal trends, but details are little known. This study explores associations between mortality and temperature in two European capitals—Sofia and London—using four years of daily deaths, air pollution, and weather data. Design: Generalised additive models were used to permit non-linear modelling of confounders such as season and humidity, and to show the shape of mortality-temperature relations—using both two day and two week average temperatures separately. Models with linear terms for heat and cold were used to estimate lags of effect, linear effects, and attributable fractions. Participants: 44 701 all age all cause deaths in Sofia (1996–1999) and 256 464 in London (1993–1996). Main results: In London, for each degree of extreme cold (below the 10th centile of the two week mean temperature), mortality increased by 4.2% (95% CI 3.4 to 5.1), and in Sofia by 1.8% (0.6 to 3.9). For each degree rise above the 95th centile of the two day mean, mortality increased by 1.9% (1.4 to 2.4) in London, and 3.5% (2.2 to 4.8) in Sofia. Cold effects appeared after lags of around three days and lasted—particularly in London—at least two weeks. Main heat effects occurred more promptly. There were inverse associations at later lags for heat and cold in Sofia. Conclusions: Average temperatures over short periods do not adequately model cold, and may be inadequate for heat if they ignore harvesting effects. Cold temperatures in London, particularly, seem to harm the general population and the effects are not concentrated among persons close to death. PMID:12883072

  14. An audit of HIV treatment outcomes in a UK inner city cohort.

    PubMed

    Bird, E; Cormack, I; Rodgers, M; Phillips, D; Elgalib, A

    2016-10-01

    We describe the demographics and treatment outcomes of a HIV-infected cohort from Croydon University Hospital, London, UK. We showed that the Croydon Cohort had good viral load suppression (98.6% with viral load < 100 copies/ml and 99.0% with viral load < 200 copies/ml) despite being a potentially challenging cohort in a deprived area of London. The viral load outcomes are better than the Public Health England data from 2014 and the latest British HIV Association audit using data from 2009.

  15. CAP in the UK

    NASA Astrophysics Data System (ADS)

    Haley, P.

    2008-06-01

    This poster highlights some of the experiential learning activities used by The SHARE Initiative (TSI) in the UK. Past, present and future projects are described and the possibility of linking up internationally with other projects is invited. Digital media, scientific heritage and solar physics are three areas which Paul Haley (Director - TSI) is particularly keen to develop. Operating as a community interest company TSI outreaches astronomy activities directly into rural areas in the UK.

  16. Listening to those on the frontline: service users’ experiences of London tuberculosis services

    PubMed Central

    Boudioni, Markella; McLaren, Susan; Belling, Ruth; Woods, Leslie

    2011-01-01

    Aim: To explore tuberculosis (TB) service users’ experiences and satisfaction with care provision. Background: Thirty-nine percent of all new UK TB cases occur in London. Prevalence varies considerably between and within boroughs. Overall, research suggests inadequate control of London’s TB transmission; TB has become a health care priority for all London Primary Care Trusts. Service users’ experiences and satisfaction with care provision have not been explored adequately previously. Methods: A qualitative research design, using semi-structured face-to-face interviews was used. Ten service users, purposively selected in key risk groups across London, were interviewed. All interviews were digitally recorded with users’ permission, transcribed verbatim, and analyzed thematically. Results: Participants were treated in local hospitals for 6–12 months. Treatment was administered by TB nurses to inpatients and outpatients receiving directly observed therapy in consultation with medical staff and home visits for complex cases. Two participants did not realize the importance of compliance. Overall, they were satisfied with many TB services’ aspects, communication, and service organization. Early access, low suspicion index amongst some GPs, and restricted referral routes were identified as service barriers. Other improvement areas were information provision on drug side effects, diet, nutritional status, and a few health professionals’ attitudes. The effects on people varied enormously from minimal impact to psychological shock; TB also affected social and personal aspects of their life. With regard to further support facilities, some positive views on managed accommodation by TB-aware professionals for those with accommodation problems were identified. Conclusion: This first in-depth study of TB service users’ experiences across London offers valuable insights into service users’ experiences, providing information and recommendations for a strategic

  17. Promoting SETI in the UK

    NASA Astrophysics Data System (ADS)

    Penny, Alan

    2013-10-01

    MEETING REPORT What does the UK presently do in the search for extraterrestrial intelligence and what are the plans for the future? Alan Penny reports on a meeting of UK academics active in SETI, held as sessions in the recent National Astronomy Meeting in Scotland - and the formation of the UK SETI Research Network to promote UK academic work.

  18. UK Secondary Schools under Surveillance: What Are the Implications for Race? A Critical Race and Butlerian Analysis

    ERIC Educational Resources Information Center

    Chadderton, Charlotte

    2012-01-01

    Since September 11th 2001, and the London bombings of July 2005, the "war on terror" has led to the subjection of populations to new regimes of control and reinforced state sovereignty. This involves, in countries such as the UK and the US, the limiting of personal freedoms, increased regulation of immigration and constant surveillance,…

  19. Finding a VOICE for UK clinical pharmacology

    PubMed Central

    Aronson, Jeffrey K

    2012-01-01

    At a James Black Conference held in Oxford on 20–22 June 2011, a group of senior clinical pharmacologists and their junior colleagues, other medical specialists, and pharmacists discussed an agenda for UK clinical pharmacology for the next 5 years, addressing the following broad questions. How should UK clinical pharmacology be further developed and delivered as a discipline in universities, the NHS, pharmaceutical companies, and regulatory authorities? How should teaching and training in UK clinical pharmacology and therapeutics be delivered and assessed? What topics should be priorities for research in UK academic clinical pharmacology? How should clinical pharmacology contribute to UK drugs policy? How should pharmacology and clinical pharmacology be further integrated, to the benefit of both? Numerous recommendations emerged, under the collective acronym VOICE, standing for Visibility, Outreach, Integration, Coverage and Emissaries. Visibility The visibility of the discipline needs to be increased. This could be done, for example, by increased activities in acute general medicine/toxicology, through activities of Medicines and Therapeutics Committees, participation in grand rounds, teaching and training, and monitoring therapeutic interventions, and by offering bolt-on training for other specialists (for example, short courses, MSc courses, and training programmes). Outreach Methods of increasing outreach include roadshows in schools/medical schools, national special study modules, public education, press coverage, and social marketing. Integration Closer collaborations with pharmacologists, clinical pharmacists, other prescribers, and pharmaceutical companies (e.g. through joint training programmes) are desirable. Coverage Attention to neglected areas, such as general practice, paediatrics, obstetrics, geriatrics, anaesthetics, cancer, and immunology. Emissaries Trainees to spread the word. PMID:22360150

  20. Finding a VOICE for UK clinical pharmacology.

    PubMed

    Aronson, Jeffrey K

    2012-06-01

    At a James Black Conference held in Oxford on 20-22 June 2011, a group of senior clinical pharmacologists and their junior colleagues, other medical specialists, and pharmacists discussed an agenda for UK clinical pharmacology for the next 5 years, addressing the following broad questions. How should UK clinical pharmacology be further developed and delivered as a discipline in universities, the NHS, pharmaceutical companies, and regulatory authorities? How should teaching and training in UK clinical pharmacology and therapeutics be delivered and assessed? What topics should be priorities for research in UK academic clinical pharmacology? How should clinical pharmacology contribute to UK drugs policy? How should pharmacology and clinical pharmacology be further integrated, to the benefit of both? Numerous recommendations emerged, under the collective acronym VOICE, standing for Visibility, Outreach, Integration, Coverage and Emissaries. VISIBILITY: The visibility of the discipline needs to be increased. This could be done, for example, by increased activities in acute general medicine/toxicology, through activities of Medicines and Therapeutics Committees, participation in grand rounds, teaching and training, and monitoring therapeutic interventions, and by offering bolt-on training for other specialists (for example, short courses, MSc courses, and training programmes). OUTREACH: Methods of increasing outreach include roadshows in schools/medical schools, national special study modules, public education, press coverage, and social marketing. INTEGRATION: Closer collaborations with pharmacologists, clinical pharmacists, other prescribers, and pharmaceutical companies (e.g. through joint training programmes) are desirable. COVERAGE: Attention to neglected areas, such as general practice, paediatrics, obstetrics, geriatrics, anaesthetics, cancer, and immunology. EMISSARIES: Trainees to spread the word.

  1. Gonorrhoea in inner London: results of a cross sectional study.

    PubMed Central

    Low, N.; Daker-White, G.; Barlow, D.; Pozniak, A. L.

    1997-01-01

    OBJECTIVES: To estimate population based incidence rates of gonorrhoea in an inner London area and examine relations with age, ethnic group, and socioeconomic deprivation. DESIGN: Cross sectional study. SETTING: 11 departments of genitourinary medicine in south and central London. SUBJECTS: 1978 first episodes of gonorrhoea diagnosed in 1994 and 1995 in residents of 73 electoral wards in the boroughs of Lambeth, Southwark, and Lewisham who attended any of the departments of genitourinary medicine. MAIN OUTCOME MEASURES: Yearly age, sex, and ethnic group specific rates of gonorrhoea per 100,000 population aged 15-59 years; rate ratios for the effects of age and ethnic group on gonorrhoea rates in women and men before and after adjustment for confounding factors. RESULTS: Overall incidence rates of gonorrhoea in residents of Lambeth, Southwark, and Lewisham were 138.3 cases yearly per 100,000 women and 291.9 cases yearly per 100,000 men aged 15-59 years. At all ages gonorrhoea rates were higher in non-white minority ethnic groups. Rate ratios for the effect of age adjusted for ethnic group and underprivilege were 15.2 (95% confidence interval 11.6 to 19.7) for women and 2.0 (1.7 to 2.5) for men aged 15-19 years compared with those over 30. After deprivation score and age were taken into account, women from black minority groups were 10.5 (8.6 to 12.8) times as likely and men 11.0 (9.7 to 12.6) times as likely as white people to experience gonorrhoea. CONCLUSIONS: Gonorrhoea rates in Lambeth, Southwark, and Lewisham in 1994-5 were six to seven times higher than for England and Wales one year earlier. The presentation of national trends thus hides the disproportionate contribution of ongoing endemic transmission in the study area. Teenage women and young adult men, particularly those from black minority ethnic groups, are the most heavily affected, even when socioeconomic underprivilege is taken into account. There is urgent need for resources for culturally

  2. Congressional Science Fellow tackles science policy for U.K.

    NASA Astrophysics Data System (ADS)

    Moses, Julie J.

    After an AGU Congressional Science Fellowship in 1997-1998,I decided to pursue science policy further. I spied an ad in the Sunday Washington Post advertising for someone with a science degree, who also had knowledge of the United Kingdom, and science policy experience on Capitol Hill. In addition to my Ph.D. from the University of California at Los Angeles and the Congressional Science Fellowship, I had spent two years in the U.K. as a post-doc at Queen Mary and Westfield College in London.I applied for the job, which was at the British Embassy in Washington, D.C., and was hired. The UK Foreign Office has a tradition of hiring many of its embassy staff locally; they consider knowledge of local politics and issues very use ful for their interests. Now I cover hard science issues, including space and the Internet for Her Majesty's Government.

  3. Large-scale structure in the universe. Proceedings. Conference, London (UK), 25 - 26 Mar 1998.

    NASA Astrophysics Data System (ADS)

    1999-01-01

    The following topics were dealt with: Universe: large-scale structure, early Universe: quantum fluctuations, microwave background radiation studies, the Sloan Digital Sky Survey, the 2dF Galaxy Redshift Survey, galaxy clustering evolution, the CNOC2 Field Galaxy Redshift Survey, quasar clustering.

  4. Industrial Genotoxicology Group (IGG): Aneuploidy, White House Hotel, London, UK, 16 May 1997.

    PubMed

    1998-07-01

    Aneuploidy has important consequences for human health. There is a requirement to detect aneugens that may not be fully satisfied by the current test batter. New cytogenetic techniques look promising.

  5. Highlights from Faraday Discussion 184: Single-Molecule Microscopy and Spectroscopy, London, UK, September 2015.

    PubMed

    Gellings, E; Faez, S; Piatkowski, L

    2016-02-07

    The 2015 Faraday Discussion on single-molecule microscopy and spectroscopy brought together leading scientists involved in various topics of single-molecule research. It attracted almost a hundred delegates from a broad spectrum of backgrounds and experience levels - from experimentalists to theoreticians, from biologists to materials scientists, from masters students to Nobel Prize Laureates. The meeting was merely a reflection of how big of an impact the ability to detect individual molecules has had on science over the past quarter of a century. In the following we give an overview of the topics covered during this meeting and briefly highlight the content of each presentation.

  6. A dynamic approach to urban road deposited sediment pollution monitoring (Marylebone Road, London, UK)

    NASA Astrophysics Data System (ADS)

    Crosby, C. J.; Fullen, M. A.; Booth, C. A.; Searle, D. E.

    2014-06-01

    The use of mineral magnetic measurements (χLF, χARM and SIRM) as a potential pollution proxy using road deposited sediment (RDS) is explored as an alternative means of monitoring pollution on a busy city road. Comparison of sediment-related analytical data by correlation analysis between mineral magnetic, particle size and geochemical properties is reported. Mineral magnetic concentration parameters (χLF, χARM and SIRM) reveal significant (p < 0.001; n = 61) associations with PM1.0, PM2.5 and PM10. Significant associations were also found with mineral magnetic concentrations (χLF and SIRM) and specific concentrations of the elements Fe, Ni, Cu, Zn and Mn (p < 0.001; n = 61). Inter-geochemical correlation analysis found strong associations (p < 0.001; n = 61) between Fe, Ni, Cu, Zn and Mn and suggest anthropogenic enrichment influences. Low χFD% measurements imply an influence of multi-domain mineralogy, indicative of anthropogenic combustion processes. SEM micrographs also support this, as all samples contain Fe spherules indicative of vehicular combustion processes. This study advocates rapid and simple initial assessment of urban pollution episodes using mineral magnetic measurements as a dynamic explorative technology.

  7. Digital London: Creating a Searchable Web of Interlinked Sources on Eighteenth Century London

    ERIC Educational Resources Information Center

    Shoemaker, Robert

    2005-01-01

    Purpose: To outline the conceptual and technical difficulties encountered, as well as the opportunities created, when developing an interlinked collection of web-based digitised primary sources on eighteenth century London. Design/methodology/approach: As a pilot study for a larger project, a variety of primary sources, including the "Old…

  8. Current Capabilities, Requirements and a Proposed Strategy for Interdependency Analysis in the UK

    NASA Astrophysics Data System (ADS)

    Bloomfield, Robin; Chozos, Nick; Salako, Kizito

    The UK government recently commissioned a research study to identify the state-of-the-art in Critical Infrastructure modelling and analysis, and the government/industry requirements for such tools and services. This study (Cetifs) concluded with a strategy aiming to bridge the gaps between the capabilities and requirements, which would establish interdependency analysis as a commercially viable service in the near future. This paper presents the findings of this study that was carried out by CSR, City University London, Adelard LLP, a safety/security consultancy and Cranfield University, defense academy of the UK.

  9. Air quality and public health impacts of UK airports. Part II: Impacts and policy assessment

    NASA Astrophysics Data System (ADS)

    Yim, Steve H. L.; Stettler, Marc E. J.; Barrett, Steven R. H.

    2013-03-01

    The potential adverse human health impacts of emissions from UK airports have become a significant issue of public concern. We produce an inventory of UK airport emissions - including emissions from aircraft landing and takeoff operations, aircraft auxiliary power units (APUs) and ground support equipment (GSE) - with quantified uncertainty. Emissions due to more than 95% of UK passenger enplanements are accounted for. We apply a multi-scale air quality modelling approach to assess the air quality impacts of UK airports. Using a concentration-response function we estimate that 110 (90% CI: 72-160) early deaths occur in the UK each year (based on 2005 data) due to UK airport emissions. We estimate that up to 65% of the health impacts of UK airports could be mitigated by desulphurising jet fuel, electrifying GSE, avoiding use of APUs and use of single engine taxiing. Two plans for the expansion of UK airport capacity are examined - expansion of London Heathrow and new hub airport in the Thames Estuary. Even if capacity is constrained, we find that the health impacts of UK airports still increases by 170% in 2030 due to an increasing and aging population, increasing emissions, and a changing atmosphere. We estimate that if Heathrow were to be expanded as per previous UK Government plans, UK-wide health impacts in 2030 would increase by 4% relative to the 2030 constrained case, but this increase could become a 48% reduction if emissions mitigation measures were employed. We calculate that 24% of UK-wide aviation-attributable early deaths could be avoided in 2030 if Heathrow were replaced by a new airport in Thames Estuary because the location is downwind of London, where this reduction occurs notwithstanding the increase in aircraft emissions. A Thames hub airport would (isolated from knock-on effects at other airports) cause 60-70% fewer early deaths than an expanded Heathrow, or 55-63% fewer early deaths than an unexpanded Heathrow. Finally, replacing Heathrow by a

  10. Non-European nurses' perceived barriers to UK nurse registration.

    PubMed

    Allan, Helen; Westwood, Sue

    2016-05-11

    Aim To conduct a scoping project to identify perceived barriers to UK nurse registration as experienced by internationally educated nurses working as healthcare assistants in the UK. Method Eleven internationally educated nurses working as healthcare assistants in two London hospitals attended two facilitated focus groups. Qualitative thematic analysis was used to analyse the data. Findings Study participants articulated frustration with UK English language testing requirements and a sense of injustice and unfairness relating to: double standards for nurses educated within and outside of the European Union (EU) and European Economic Area (EEA); and what was perceived, by some, as arbitrary English language testing with unnecessarily high standards. Differences among study participants related to issues of competency and accountability regarding English language skills and passing English language skills tests, with many feeling they were playing 'a game' where the rules kept changing. Conclusion Language testing barriers are impeding UK nurse registration for some internationally educated nurses from outside the EU and EEA who, as a result, are working as healthcare assistants. The provision of English language training by employers would improve their prospects of achieving nurse registration.

  11. Response of London's urban heat island to a marine air intrusion in an easterly wind regime

    NASA Astrophysics Data System (ADS)

    Chemel, C.; Sokhi, R. S.

    2010-09-01

    the urban boundary layer and the intensity of the UHI are also examined through numerical simulations. The advection of cooler air from the North Sea reduces the UHI on the windward suburbs and displaces it several kilometres to the west, in good agreement with observations. Passive tracers are released within the urban area to investigate the impact of the marine air intrusion on transport characteristics above London's atmosphere. Cooler air advection across London was found to efficiently cleanse the urban area of passive tracers. Implications for urban air quality are discussed in the light of results from this case study. This study has been conducted as part the Clean Air for London (ClearfLo) project, funded by the UK National Environment Research Council (NERC).

  12. Spatial and temporal associations of road traffic noise and air pollution in London: Implications for epidemiological studies.

    PubMed

    Fecht, Daniela; Hansell, Anna L; Morley, David; Dajnak, David; Vienneau, Danielle; Beevers, Sean; Toledano, Mireille B; Kelly, Frank J; Anderson, H Ross; Gulliver, John

    2016-03-01

    Road traffic gives rise to noise and air pollution exposures, both of which are associated with adverse health effects especially for cardiovascular disease, but mechanisms may differ. Understanding the variability in correlations between these pollutants is essential to understand better their separate and joint effects on human health. We explored associations between modelled noise and air pollutants using different spatial units and area characteristics in London in 2003-2010. We modelled annual average exposures to road traffic noise (LAeq,24h, Lden, LAeq,16h, Lnight) for ~190,000 postcode centroids in London using the UK Calculation of Road Traffic Noise (CRTN) method. We used a dispersion model (KCLurban) to model nitrogen dioxide, nitrogen oxide, ozone, total and the traffic-only component of particulate matter ≤2.5μm and ≤10μm. We analysed noise and air pollution correlations at the postcode level (~50 people), postcodes stratified by London Boroughs (~240,000 people), neighbourhoods (Lower layer Super Output Areas) (~1600 people), 1km grid squares, air pollution tertiles, 50m, 100m and 200m in distance from major roads and by deprivation tertiles. Across all London postcodes, we observed overall moderate correlations between modelled noise and air pollution that were stable over time (Spearman's rho range: |0.34-0.55|). Correlations, however, varied considerably depending on the spatial unit: largest ranges were seen in neighbourhoods and 1km grid squares (both Spearman's rho range: |0.01-0.87|) and was less for Boroughs (Spearman's rho range: |0.21-0.78|). There was little difference in correlations between exposure tertiles, distance from road or deprivation tertiles. Associations between noise and air pollution at the relevant geographical unit of analysis need to be carefully considered in any epidemiological analysis, in particular in complex urban areas. Low correlations near roads, however, suggest that independent effects of road noise and

  13. [The regulatory framework for complementary and alternative medicines in Europe].

    PubMed

    Knöss, Werner; Stolte, F; Reh, K

    2008-07-01

    Medicinal products from complementary and alternative medicine are in Germany a regular part of the health care system. Herbal, homeopathic, anthroposophic and traditional medicinal products are highly accepted by the population. The German Medicines Act obliged the competent authorities to consider the particular characteristics of complementary and alternative medicines. The European regulatory framework defined the status of herbal medicinal products, traditional herbal medicinal products and homeopathic medicinal products within the directive 2001/83/EC. The committee for herbal medicinal products (HMPC) was established at the European Medicines Agency in London (EMEA); for homeopathic medicinal products there is a specific working group established by the Heads of Medicines Agencies. Harmonisation of medicinal products from complementary and alternative and traditional medicine in Europe was enforced by implementation of directive 2001/83/EC in national legislations of member states. The provisions of this directive will substantially influence the development of the European market during the forthcoming years.

  14. Age estimation in Portuguese population: The application of the London atlas of tooth development and eruption.

    PubMed

    Pavlović, Strahinja; Palmela Pereira, Cristiana; Vargas de Sousa Santos, Rui Filipe

    2017-03-01

    Chronological age estimation from the dental parameters is becoming increasingly important. The London atlas of tooth development is the most recent developed method and represents a modification of the previous older methods. The aim of this study was to evaluate the accuracy of the London atlas for the dental age estimation in the Portuguese population. The study sample included 736 radiographic images (498 females and 238 males) of Portuguese origin, patients of Dental Clinic of Superior Institute of Health Sciences Egas Moniz and Dental Medicine Faculty, University of Lisbon. The age range of the individuals was between 3 and 24 years. Estimated age was compared with the chronological age using the paired t-test. The results showed that there was no statistically significant difference between left and right side of the jaw (p>0.05). Both sides showed an average overestimation of age by one month approximately. Moreover, the significant difference between chronological and estimated age was not observed in the females. However, the significant difference was observed in a sample coming from males (right: p=0.008; left: p=0.003). Our results showed that the London atlas can be potentially used as a tool for age estimation. However, the difference between sexes clearly suggests that separate charts should be made for each sex. Further studies, which will have as a final goal the development of a new method for age estimation using dental parameters, are needed.

  15. Honor, brotherhood, and the corporate ethos of London's Barber-Surgeons' Company, 1570-1640.

    PubMed

    Chamberland, Celeste

    2009-07-01

    As the largest and most civically active body of medical practitioners in the late Tudor and early Stuart period, surgeons played a vital role in London's urban landscape, but remained precariously vulnerable to abasement due to the regular contact with death and disease necessitated by their work. Based on an analysis of guild records, printed surgical manuals, and conduct literature, this study explores the emergent corporate ethos of London's Barber-Surgeons' Company and addresses the identity formation of surgeons in the late-sixteenth and early-seventeenth centuries. By implementing codes of conduct and uniform standards of practice, punishing transgressions of propriety, and developing legislation to limit the activities of unlicensed and foreign practitioners, Company officers ardently sought social and occupational legitimacy within a milieu characterized by a tremendous emphasis on status and hierarchy. Rooted in methodology drawn from the social history of medicine and cultural anthropology, this study argues that in response to the persistent stigma associated with their work and London's increasingly prevalent culture of credit, surgeons, like other artisanal groups, sought to enhance their social legitimacy and occupational respectability by manipulating contemporary social rituals, reinforcing the honorable associations of their work, and preserving the veneer of brotherhood and camaraderie.

  16. Practicing Reflexivity in the Study of Italian Migrants in London

    ERIC Educational Resources Information Center

    Seganti, Francesca Romana

    2010-01-01

    This article discusses the centrality of reflexivity in qualitative research through examples from my study on the role new media play in the lives of Italians in London. My hypothesis was that Italians were "in transit" in London and they were using new media to build "temporary" communities. I conducted in-depth interviews…

  17. 33 CFR 110.147 - New London Harbor, Conn.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... emergencies, vessels shall not anchor in New London Harbor or the approaches thereto outside the anchorages... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false New London Harbor, Conn. 110.147 Section 110.147 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY...

  18. Alternative Spaces of Learning in East London: Opportunities and Challenges

    ERIC Educational Resources Information Center

    Sneddon, Raymonde; Martin, Peter

    2012-01-01

    This article emerges from an ongoing exploration into how British minority ethnic communities in the London area create spaces in community-based programs to maintain or develop their languages and literacies. In London, more than one-third of the 850,000 school children speak a language other than English at home (Baker & Eversley, 2000).…

  19. Changing the Subject: English in London, 1945-1967

    ERIC Educational Resources Information Center

    Yandell, John

    2014-01-01

    Two recent books, "English Teachers in a Postwar Democracy: Emerging Choice in London Schools, 1945-1965" and "The London Association for the Teaching of English, 1947-67: A History," explore an important period in the development of English as a school subject and in the remaking of the professional identity of English…

  20. Education in a Global City: Essays from London

    ERIC Educational Resources Information Center

    Brighouse, Tim, Ed.; Fullick, Leisha, Ed.

    2007-01-01

    This collection of essays by academic and policy experts brings together a wide range of data to offer a clear picture of London's changing education scene. Its mapping of new and developing strategies for successful urban education will be useful to educators and policymakers not only in London but also in other cities operating in similar…

  1. London in Space and Time: Peter Ackroyd and Will Self

    ERIC Educational Resources Information Center

    Green, Andrew

    2013-01-01

    This paper explores the treatment of London by two authors who are profoundly influenced by the concept of the power of place and the nature of urban space. The works of Peter Ackroyd, whose writings embody, according to Onega (1997, p. 208) "[a] yearning for mythical closure" where London is "a mystic centre of…

  2. RADIOLOGICAL SURVEY AT THE NEW LONDON HARBOR FACILITIES

    EPA Science Inventory

    A radiological survey done to assess levels of environmental radioactivity in and around navy harbor facilities located on the Thames River near New London, Connecticut. These facilities include the New London Submarine Base at Groton, the Electric Boat Company at Groton, Sound ...

  3. Birthweight by gestational age and its effect on perinatal mortality in white and in Punjabi births: experience at a district general hospital in West London 1967-1975.

    PubMed

    Dawson, I; Golder, R Y; Jonas, E G

    1982-11-01

    At Hillingdon Hospital in West London two main ethnic groups: 'UK' (i.e. white European) and 'Indian' (i.e. Punjabi) account for the bulk of obstetric work load. Birthweight by gestational age graphs were calculated for some 6000 Indian and 18000 UK infants born between 1967 and 1975 inclusive. A mean weight difference at term favoured UK male babies by 240 g and UK female babies by 230 g. Though the crude perinatal results in the two populations were not significantly different, the perinatal mortality of infants less than 2500 g in birthweight was lower in the Indian than the UK population, particularly in the 1500-2400 g group. This is attributed to a levelling off in intrauterine growth from 36 to 37 weeks gestation onwards in Indian compared with UK pregnancies, so that they were more mature than UK births of the same weight. However light-for-dates births, defined as birthweights below the 10th centile of weight-for-gestational age on their own ethnic and sex specific standards pose problems, irrespective of ethnic background.

  4. "Circumcision", culture, and health-care provision in Tower Hamlets, London.

    PubMed

    Cameron, J; Anderson, K R

    1998-11-01

    Tower Hamlets (London, England) has a sizable Somali community whose members maintain close links with their families in Africa. The London Black Women's Health Action Project (LBWAP) was established in Tower Hamlets, in 1982, to address the health needs of Somali women, especially those related to female circumcision. The major focus in the UK has been on protecting girls from undergoing this practice, with little attention to the needs of women who have already been circumcised. Of 200 Somali women interviewed by LBWAP, 61% had been infibulated in their native country by people with no medical training. Among the long-term health consequences were dysmenorrhea, recurrent urinary problems, urethral damage, and painful intercourse. Although deinfibulation can be obtained, both health care professionals and circumcised women tend to be unaware of this service. LBWAP has proposed a study to assess the expressed health care needs of circumcised Somali women and match these desires with actual health care provision. To raise the consciousness of British health care professionals, parallels between female circumcision and the indiscriminate, unnecessary use of episiotomy are being made.

  5. The Dependence on Smokeless Tobacco in the South Asian Communities in East London

    PubMed Central

    Khaja, Amjad Hussain; Zwiad, Abdulsalam Ali; Tarakji, Bassel; Gazal, Giath; Albaba, Feras; KalajI, Nader; Petro, Waleed

    2016-01-01

    Background & Objective: The purpose of the study was to understand the dependency on smokeless tobacco. Methods: The major aspect of the interview was to study the type of chewing tobacco used, frequency of purchase of chewing tobacco, change in attitude and behavior after the use of chewing tobacco. This study was done in 2005 in London. Of the 110 respondents interviewed 88 were used for the data analysis. Study Design: An exploratory study was conducted in East London, United Kingdom. The selected sample was interviewed through a questionnaire, based on the Severson Smokeless Tobacco Dependence Scale. Results: Cross tabulations report that in a sample of 88 South Asian UK resident men 46.6% used leaf (paan), 43.2% used processed form of chewing tobacco and 10.2% used gutka. Older age (67%) respondents were more likely than the younger age (30%) respondents to chew tobacco. The frequency of purchase of chewing tobacco is reported high (67.2%) in the older age group than the younger age group (50%). Conclusion: This current study used an amended form of the Severson Smokeless Tobacco Scale questionnaire to study the dependency on smokeless tobacco. The study could be developed in the selection of the sample, which would include both males and females to study the dependency on smokeless tobacco. PMID:26234985

  6. A tale of two cities: Comparison of impacts on CO2 emissions, the indoor environment and health of home energy efficiency strategies in London and Milton Keynes

    NASA Astrophysics Data System (ADS)

    Shrubsole, C.; Das, P.; Milner, J.; Hamilton, I. G.; Spadaro, J. V.; Oikonomou, E.; Davies, M.; Wilkinson, P.

    2015-11-01

    Dwellings are a substantial source of global CO2 emissions. The energy used in homes for heating, cooking and running electrical appliances is responsible for a quarter of current total UK emissions and is a key target of government policies for greenhouse gas abatement. Policymakers need to understand the potential impact that such decarbonization policies have on the indoor environment and health for a full assessment of costs and benefits. We investigated these impacts in two contrasting settings of the UK: London, a predominantly older city and Milton Keynes, a growing new town. We employed SCRIBE, a building physics-based health impact model of the UK housing stock linked to the English Housing Survey, to examine changes, 2010-2050, in end-use energy demand, CO2 emissions, winter indoor temperatures, airborne pollutant concentrations and associated health impacts. For each location we modelled the existing (2010) housing stock and three future scenarios with different levels of energy efficiency interventions combined with either a business-as-usual, or accelerated decarbonization of the electricity grid approach. The potential for CO2 savings was appreciably greater in London than Milton Keynes except when substantial decarbonization of the electricity grid was assumed, largely because of the lower level of current energy efficiency in London and differences in the type and form of the housing stock. The average net impact on health per thousand population was greater in magnitude under all scenarios in London compared to Milton Keynes and more beneficial when it was assumed that purpose-provided ventilation (PPV) would be part of energy efficiency interventions, but more detrimental when interventions were assumed not to include PPV. These findings illustrate the importance of considering ventilation measures for health protection and the potential variation in the impact of home energy efficiency strategies, suggesting the need for tailored policy

  7. A Portable Low-Cost High Density Sensor Network for Air Quality at London Heathrow Airport

    NASA Astrophysics Data System (ADS)

    Popoola, O. A.; Mead, M. I.; Bright, V. B.; North, R.; Stewart, G.; Kaye, P. H.; Jones, R. L.

    2013-12-01

    The growing demand for air travel in the UK has led to calls for ways to address the effects of increasing activities in airports in London. London Heathrow airport (LHR) is the largest airport in the UK and in recent years has been operating close to full capacity resulting in consideration of building a third runway to ease the burden at the airport. Such an expansion would be subject to meeting several criteria including local air quality challenges. Air quality issues associated with the airport include particulates (e.g. PM2.5, PM10), carbon monoxide (CO), oxides of nitrogen (NO, NO2), sulphur dioxide (SO2) and volatile organic compounds (VOCs), and these are associated with different sources including aircraft activities and road traffic within and outside of the airport. Although it is well known that airports contribute to poor air quality, part of the challenge is to quantify contributions from these different sources. The work presented here shows the utility of low-cost high density sensor networks in addressing this challenge. We have shown in previous studies the application of low-cost electrochemical sensor network instruments in monitoring air quality pollutants including CO, NO and NO2 in an urban environment. In this paper we extend this to include modified versions of these instruments which incorporate additional species such as O3, SO2, VOCs, CO2 as well as size-speciated particulates (0.38 to 17.4 μm). Meteorological data including temperature, relative humidity, wind speed and direction are also recorded. For this paper, we focus on LHR, although the technique has much wider applicability. A network of 30 sensor nodes is being deployed for over 16 months in and around LHR as part of NERC funded Sensor Network for Air Quality (SNAQ) project. We present here some of the early results from the deployment showing source attribution associated with different operational modes at LHR. Regional pollution episodes influenced by macro meteorology are

  8. Volatile organic compound fluxes and concentrations in London (ClearfLo)

    NASA Astrophysics Data System (ADS)

    Valach, Amy; Langford, Ben; Nemitz, Eiko; MacKenzie, Rob; Hewitt, Nick

    2014-05-01

    Volatile organic compounds (VOCs) from anthropogenic sources such as fuel combustion or evaporative emissions can directly and indirectly affect human health. Some VOCs, such as benzene and 1,3- butadiene are carcinogens. These and other VOCs contribute to the formation of ozone (O3) and aerosol particles, which have effects on human health and the radiative balance of the atmosphere. Although in the UK VOC emissions are subject to control under European Commission Directive 2008/50/EC and emission reducing technologies have been implemented, urban air pollution remains a concern. Urban air quality is likely to remain a priority since currently >50% of the global population live in urban areas with trends in urbanization and population migration predicted to increase. The ClearfLo project is a large multi-institutional consortium funded by the UK Natural Environment Research Council (NERC) and provides integrated measurements of meteorology, gas phase and particulate composition of the atmosphere over London. Both long term and IOP measurements were made at street and elevated locations at a range of sites across London and its surroundings during 2011 and 2012. Mixing ratios of a selection of nine VOCs were measured using a high sensitivity proton transfer reaction-mass spectrometer (PTR-MS) at a ground level urban background (North Kensington) and kerbside (Marylebone Road) site during the winter IOP. VOC fluxes were measured by virtually disjunct eddy covariance (vDEC) at an elevated urban site (King's College Strand) in Aug-Dec 2012. Our results for the first IOP showed that most of the selected compound concentrations depended on traffic emissions, although there was a marked difference between the urban background and kerbside sites. We identified some temperature effects on VOC concentrations. We also present the first analyses of VOC flux measurements over London. Preliminary analyses indicate most compounds associated with vehicle emissions closely

  9. Lidar Observations of Pollution Transport From London to Rural Areas

    NASA Astrophysics Data System (ADS)

    Ricketts, Hugo; Vaughan, Geraint; Wareing, David

    2016-06-01

    The Clean Air for London (ClearfLo) Project took place in and around London, United Kingdom. The aim of the project was to learn how both atmospheric dynamics and chemistry affect air pollution in the south east of England. During the winter and summer of 2012 many different types of instrument including lidars were deployed throughout London city centre, suburbs and into rural areas. Amongst these instruments was the Boundary Layer Aerosol/Ozone Lidar owned by the National Centre for Atmospheric Sciences (NCAS) in the United Kingdom. Ozone and aerosol data are presented from data collected during July and August 2012 and compared to back trajectories to identify their origins.

  10. Teaching the History of Astronomy On Site in London

    NASA Astrophysics Data System (ADS)

    French, Linda M.

    2016-01-01

    In the autumn of 2014, the author had the opportunity to teach a class on the history of astronomy in England as part of a study abroad experience for students at Illinois Wesleyan University. The philosophy of the program is to use the rich cultural environment of London as a setting for active learning. In the classroom, students read and discussed selected works by Ptolemy, Copernicus, Kepler, Galileo, and Herschel. We visited Stonehenge, the Royal Greenwich Observatory, the London Science Museum, the London Monument, and the library of the Royal Astronomical Society. Lessons learned from the experience will be shared.

  11. Medical student experience of London general practice teaching attachments.

    PubMed

    Schamroth, A J; Haines, A P; Gallivan, S

    1990-07-01

    Forty-eight students kept a log diary of activities during their central London general practice teaching attachments associated with the Department of Primary Health Care of University College and Middlesex School of Medicine. The students each saw on average 96 patients per week, of whom 69% were discussed by the general practitioner with the student after the consultation. Students spent an average of 21.5 hours a week sitting in with the general practitioner. While most of this time was as a passive observer, the students were also able to participate more actively, personally taking histories for a median of 1.25 hours a week and personally examining patients for a median of 1.7 hours a week. During these periods of active involvement each student personally took a mean of 10 short and 2.5 long histories per week and performed a mean of 25.5 short and 1.2 long examinations per week. General practitioners to whom the students were attached spent a mean of 4 hours a week on (patient-oriented) teaching. The tuition was highly rated by the students in terms of both usefulness and stimulation. Students also received a mean of 2.3 hours a week of teaching from other members of the primary health care team, which was somewhat less well received. Areas for improvement were: the relatively few home visits (median of 6 per week) per student; the limited time students spent on self-education (average of 65 minutes per week); and the few practical procedures performed by the students. Students could also be encouraged to play a more active role in examining and interviewing patients.

  12. Tuberculosis in London: the importance of homelessness, problem drug use and prison

    PubMed Central

    Story, A; Murad, S; Roberts, W; Verheyen, M; Hayward, A C

    2007-01-01

    Background The control of tuberculosis (TB) is founded on early case detection and complete treatment of disease. In the UK, TB is concentrated in subgroups of the population in large urban centres. The impact of homelessness, imprisonment and problem drug use on TB control in London is reviewed. Methods A cohort study was undertaken of all patients with TB in Greater London to determine the point prevalence of disease in different groups and to examine risk factors for smear positivity, drug resistance, treatment adherence, loss to follow‐up and use of directly observed therapy (DOT). Results Data were collected on 97% (1941/1995) of eligible patients. The overall prevalence of TB was 27 per 100 000. An extremely high prevalence of TB was seen in homeless people (788/100 000), problem drug users (354/100 000) and prisoners (208/100 000). Multivariate analysis showed that problem drug use was associated with smear positive disease (OR 2.2, p<0.001), being part of a known outbreak of drug resistant TB (OR 3.5, p = 0.001) and loss to follow‐up (OR 2.7, p<0.001). Imprisonment was associated with being part of the outbreak (OR 10.3, p<0.001) and poor adherence (OR 3.9, p<0.001). Homelessness was associated with infectious TB (OR 1.6, p = 0.05), multidrug resistance (OR 2.1, p = 0.03), poor adherence (OR 2.5, p<0.001) and loss to follow‐up (OR 3.8, p<0.001). In London, homeless people, prisoners and problem drug users collectively comprise 17% of TB cases, 44% of smear positive drug resistant cases, 38% of poorly compliant cases and 44% of cases lost to follow‐up. 15% of these patients start treatment on DOT but 46% end up on DOT. Conclusions High levels of infectious and drug resistant disease, poor adherence and loss to follow‐up care indicate that TB is not effectively controlled among homeless people, prisoners and problem drug users in London. PMID:17289861

  13. The Centre for History in Public Health at the London School of Hygiene and Tropical Medicine, University of London (LSHTM)

    ERIC Educational Resources Information Center

    Berridge, Virginia

    2008-01-01

    This article describes the origin of the Centre for History in Public Health and the significance of its location in a leading school of public health. It is in three parts: (1) A brief history of how the AIDS programme became the History Centre; (2) The distinctive approach of the Centre's staff as historians: their contribution and its…

  14. Radiotherapy in the UK

    SciTech Connect

    Ramsay, S.

    1993-10-09

    What is wrong with radiation treatment in the UK Is it bad practice or merely bad publicity Between 1982 and 1991, 1,000 patients receiving isocentric radiation therapy at the North Staffordshire Royal Infirmary received a substantial underdose of radiation; the clinical report on this incident was published last week. The operator had been using a correction factor for tumor-to-skin distance, unaware that this factor had already been applied by the computer system. Although the report pointed out that it is not surprising that the clinicians were not alerted to the undertreatment, is also noted that there were no resources at the hospital to audit the outcome of radiotherapy.

  15. 96. Connecticut River Bridge. Old Lyme, New London Co., CT. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    96. Connecticut River Bridge. Old Lyme, New London Co., CT. Sec. 4209, MP 106.89. - Northeast Railroad Corridor, Amtrak Route between New York/Connecticut & Connecticut/Rhode Island State Lines, New Haven, New Haven County, CT

  16. 104. Connecticut River Bridge draw span. Old Lyme, New London ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    104. Connecticut River Bridge draw span. Old Lyme, New London Co., CT. Sec. 4209, MP 106.89. - Northeast Railroad Corridor, Amtrak Route between New York/Connecticut & Connecticut/Rhode Island State Lines, New Haven, New Haven County, CT

  17. 98. Connecticut River Bridge. Old Lyme, New London Co., CT. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    98. Connecticut River Bridge. Old Lyme, New London Co., CT. Sec. 4209, MP 106.89. - Northeast Railroad Corridor, Amtrak Route between New York/Connecticut & Connecticut/Rhode Island State Lines, New Haven, New Haven County, CT

  18. 101. Connecticut River Bridge. Old Lyme, New London Co., CT. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    101. Connecticut River Bridge. Old Lyme, New London Co., CT. Sec. 4209, MP 106.89. - Northeast Railroad Corridor, Amtrak Route between New York/Connecticut & Connecticut/Rhode Island State Lines, New Haven, New Haven County, CT

  19. 97. Connecticut River Bridge. Old Lyme, New London Co., CT. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    97. Connecticut River Bridge. Old Lyme, New London Co., CT. Sec. 4209, MP 106.89. - Northeast Railroad Corridor, Amtrak Route between New York/Connecticut & Connecticut/Rhode Island State Lines, New Haven, New Haven County, CT

  20. 102. Connecticut River Bridge. Old Lyme, New London Co., CT. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    102. Connecticut River Bridge. Old Lyme, New London Co., CT. Sec. 4209, MP 106.89. - Northeast Railroad Corridor, Amtrak Route between New York/Connecticut & Connecticut/Rhode Island State Lines, New Haven, New Haven County, CT

  1. 99. Connecticut River Bridge. Old Lyme, New London Co., CT. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    99. Connecticut River Bridge. Old Lyme, New London Co., CT. Sec. 4209, MP 106.89. - Northeast Railroad Corridor, Amtrak Route between New York/Connecticut & Connecticut/Rhode Island State Lines, New Haven, New Haven County, CT

  2. 100. Connecticut River Bridge. Old Lyme, New London Co., CT. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    100. Connecticut River Bridge. Old Lyme, New London Co., CT. Sec. 4209, MP 106.89. - Northeast Railroad Corridor, Amtrak Route between New York/Connecticut & Connecticut/Rhode Island State Lines, New Haven, New Haven County, CT

  3. 103. Connecticut River Bridge draw span. Old Lyme, New London ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    103. Connecticut River Bridge draw span. Old Lyme, New London Co., CT. Sec. 4209, MP 106.89. - Northeast Railroad Corridor, Amtrak Route between New York/Connecticut & Connecticut/Rhode Island State Lines, New Haven, New Haven County, CT

  4. The Making of Two Readers: Agatha Christie and Jack London.

    ERIC Educational Resources Information Center

    Baghban, Marcia

    1990-01-01

    Looks at the lives of two well-known writers to explore how diverse experiences produce literate adults. Discusses Agatha Christie and Jack London who used reading and writing to earn a living and to gain international reputations. (MG)

  5. Contemporary terrorism: risk perception in the London options market.

    PubMed

    Garvey, John; Mullins, Martin

    2008-02-01

    Previous studies have a demonstrated a linkage between terrorist attacks and the operation of financial markets. This article focuses on terrorist events carried out over the last five years and examines how they have been perceived among participants on the London financial market. Data from the London options market suggest a high degree of sensitivity to these events. We argue that this sensitivity reveals a vulnerability in the financial markets should the recent trends in terrorist activity continue.

  6. Simulating secondary organic aerosol from missing diesel-related intermediate-volatility organic compound emissions during the Clean Air for London (ClearfLo) campaign

    NASA Astrophysics Data System (ADS)

    Ots, Riinu; Young, Dominique E.; Vieno, Massimo; Xu, Lu; Dunmore, Rachel E.; Allan, James D.; Coe, Hugh; Williams, Leah R.; Herndon, Scott C.; Ng, Nga L.; Hamilton, Jacqueline F.; Bergström, Robert; Di Marco, Chiara; Nemitz, Eiko; Mackenzie, Ian A.; Kuenen, Jeroen J. P.; Green, David C.; Reis, Stefan; Heal, Mathew R.

    2016-05-01

    We present high-resolution (5 km × 5 km) atmospheric chemical transport model (ACTM) simulations of the impact of newly estimated traffic-related emissions on secondary organic aerosol (SOA) formation over the UK for 2012. Our simulations include additional diesel-related intermediate-volatility organic compound (IVOC) emissions derived directly from comprehensive field measurements at an urban background site in London during the 2012 Clean Air for London (ClearfLo) campaign. Our IVOC emissions are added proportionally to VOC emissions, as opposed to proportionally to primary organic aerosol (POA) as has been done by previous ACTM studies seeking to simulate the effects of these missing emissions. Modelled concentrations are evaluated against hourly and daily measurements of organic aerosol (OA) components derived from aerosol mass spectrometer (AMS) measurements also made during the ClearfLo campaign at three sites in the London area. According to the model simulations, diesel-related IVOCs can explain on average ˜ 30 % of the annual SOA in and around London. Furthermore, the 90th percentile of modelled daily SOA concentrations for the whole year is 3.8 µg m-3, constituting a notable addition to total particulate matter. More measurements of these precursors (currently not included in official emissions inventories) is recommended. During the period of concurrent measurements, SOA concentrations at the Detling rural background location east of London were greater than at the central London location. The model shows that this was caused by an intense pollution plume with a strong gradient of imported SOA passing over the rural location. This demonstrates the value of modelling for supporting the interpretation of measurements taken at different sites or for short durations.

  7. Combined Ground and Space-Based Measurements of Air Quality during the London Olympic Games 2012

    NASA Astrophysics Data System (ADS)

    Graves, R. R.; Leigh, R. J.; Singh Anand, J.; McNally, M.; Lawrence, J.; Remedios, J.; Monks, P. S.

    2012-12-01

    During July and August 2012 the Summer Olympic Games were held in London. During this period, unusually high levels of traffic and visitors to the city were expected, it is important to understand the effect this had on the air quality in London during this period. To this end three novel CityScan instruments were installed in London from the 20th July though to the end of September; affording the unique opportunity to monitor the spatial and vertical structure of nitrogen dioxide within the boundary layer in unprecedented detail. The deployment was included as part of the large NERC funded ClearfLo project (Clean Air for London) involving many other institutions and complementary measurement techniques. CityScan is a Hemispherical Scanning Imaging Differential Optical Absorption Spectrometer (HSI-DOAS) which is has been optimised to measure concentrations of nitrogen dioxide. CityScan has a 95° field of view (FOV) between the zenith and 5° below the horizon. Across this FOV there are 128 resolved elements which are measured concurrently, the spectrometer is rotated azimuthally 1° per second providing full hemispherical coverage every 6 minutes. CityScan measures concentrations of nitrogen dioxide over specific lines of sight and due to the extensive field of view of the instrument this produces measurements which are representative over city-wide scales. Nitrogen dioxide is an important air pollutant which is produced in all combustion processes and can reduce lung function; especially in sensitised individuals. These instruments aim to bridge the gap in spatial scales between point source measurements of air quality and satellite measurements of air quality offering additional information on emissions, transport and the chemistry of nitrogen dioxide. More information regarding the CityScan technique can be found at http://www.leos.le.ac.uk/aq/index.html. The first of the three CityScan instruments was located in North Kensington, the second in Soho and third

  8. Entrepreneurship and UK Doctoral Graduates

    ERIC Educational Resources Information Center

    Hooley, Tristram; Bentley, Kieran; Marriott, John

    2011-01-01

    This paper discusses the experience of UK doctoral graduates in pursuing entrepreneurial careers: there is evidence that this applies to a substantial number--about 10%--of doctoral graduates. The nature of their experience was explored using 37 interviews with doctoral entrepreneurs. The research was funded by Vitae (www.vitae.ac.uk), an…

  9. Use of non‐invasive ventilation in UK emergency departments

    PubMed Central

    Browning, J; Atwood, B; Gray, A

    2006-01-01

    Aim To describe the current use of non‐invasive ventilation in UK emergency departments. Methods A structured questionnaire was sent to all UK emergency departments assessing 25,000 new patients annually. Results 222 of 233 departments completed the questionnaire. 148 currently use non‐invasive ventilation (NIV). Most used NIV for either cardiogenic pulmonary oedema (n = 128) or chronic obstructive pulmonary disease (n = 115). Only 49 departments have protocols for NIV use and 23 audited practice. Conclusion NIV is commonly used in UK emergency departments. Practices vary significantly. One solution would be the development of guidelines on when and how to use NIV in emergency medicine practice. PMID:17130599

  10. The Struggle to Study. Financial Implications for Adults Studying in London. A Research Report Funded by London's Four Open College Networks: ALFA, CAWLOC, GLEAN, and OCSL.

    ERIC Educational Resources Information Center

    Sims, Anne; Goddard, Ty

    The four Open College Networks in London assessed the climate in inner London for adult students who wished to return to education and training. The research focussed on: the extent to which recent legislative changes threatened adult participation in education and training; the abolition of the Inner London Education Authority (ILEA) and…

  11. The secret garden? Elite metropolitan geographies in the contemporary UK

    PubMed Central

    Cunningham, Niall; Savage, Mike

    2015-01-01

    There is an enduring, indeed increasing awareness of the role of spatial location in defining and reinforcing inequality in this country and beyond. In the UK, much of the debate around these issues has focussed on the established trope of a long-standing ‘north-south divide’, a divide which appears to have deepened in recent decades with the inexorable de-industrialisation of northern Britain presented in stark counterpoint to the burgeoning concentration of wealth in London and the south-east, driven by the financial and ancillary services sectors. Due to a lack of available data, such debates have tended to focus solely on economic inequalities between places, and until now there was little understanding of how these disparities played out in the social and cultural domains. This paper significantly advances our understanding of the true meaning of spatial inequality in the UK by broadening that definition to encompass not only the economic, but also the social and cultural arenas, using data available from the BBC's Great British Class Survey experiment. We argue that these data shine a light not only on the economic inequalities between different parts of the country which existing debates have already uncovered but to understand how these are both reinforced and mediated across the social and cultural dimensions. Fundamentally, we concur with a great many others in seeing London and the south-east as a vortex for economic accumulation but it is also much more than that; it is a space where the coming together of intense economic, social and cultural resources enables the crystallisation of particular and nuanced forms of elite social class formations, formations in which place is not incidental but integral to their very existence. PMID:26640301

  12. The secret garden? Elite metropolitan geographies in the contemporary UK.

    PubMed

    Cunningham, Niall; Savage, Mike

    2015-05-01

    There is an enduring, indeed increasing awareness of the role of spatial location in defining and reinforcing inequality in this country and beyond. In the UK, much of the debate around these issues has focussed on the established trope of a long-standing 'north-south divide', a divide which appears to have deepened in recent decades with the inexorable de-industrialisation of northern Britain presented in stark counterpoint to the burgeoning concentration of wealth in London and the south-east, driven by the financial and ancillary services sectors. Due to a lack of available data, such debates have tended to focus solely on economic inequalities between places, and until now there was little understanding of how these disparities played out in the social and cultural domains. This paper significantly advances our understanding of the true meaning of spatial inequality in the UK by broadening that definition to encompass not only the economic, but also the social and cultural arenas, using data available from the BBC's Great British Class Survey experiment. We argue that these data shine a light not only on the economic inequalities between different parts of the country which existing debates have already uncovered but to understand how these are both reinforced and mediated across the social and cultural dimensions. Fundamentally, we concur with a great many others in seeing London and the south-east as a vortex for economic accumulation but it is also much more than that; it is a space where the coming together of intense economic, social and cultural resources enables the crystallisation of particular and nuanced forms of elite social class formations, formations in which place is not incidental but integral to their very existence.

  13. UK role 4 military infection services: past, present and future.

    PubMed

    Dufty, Ngozi E; Bailey, M S

    2013-09-01

    NATO describes 'Role 4' military medical services as those provided for the definitive care of patients who cannot be treated within a theatre of operations and these are usually located in a military force's country of origin and may include the involvement of civilian medical services. The UK Defence Medical Services have a proud history of developing and providing clinical services in infectious diseases and tropical medicine, sexual health and HIV medicine, and medical microbiology and virology. These UK Role 4 Military Infection Services have adapted well to recent overseas deployments, but new challenges will arise due to current military cutbacks and a greater diversity of contingency operations in the future. Further evidence-based development of these services will require leadership by military clinicians and improved communication and support for 'reach-back' services.

  14. Quantifying UK emissions of carbon dioxide using an integrative measurement strategy

    NASA Astrophysics Data System (ADS)

    Gonzi, S.; Palmer, P.

    2015-12-01

    The main objective of the Greenhouse gAs Uk and Global Emissions (GAUGE) programme is to quantify the magnitude and uncertainty of CO2, CH4 and N2O fluxes from the UK. GAUGE builds on the tall tower network established by the UK Government to estimate fluxes from England, Northern Ireland, Scotland, and Wales. The GAUGE measurement programme includes two additional tall tower sites (one in North Yorkshire and one downwind of London); regular measurements of CO2 and CH4 isotopologues; instrumentation installed on a ferry that travels daily along the eastern coast of the UK from Scotland to Belgium; a research aircraft that has been deployed on a campaign basis; and a high-density network over East Anglia that is primarily focused on the agricultural sector. We have also included satellite observations from the Japanese Greenhouse gases Observing SATellite (GOSAT) through ongoing activities within the UK National Centre for Earth Observation. In this presentation, we will present new CO2 flux estimates for the UK inferred from GAUGE measurements using a nested, high-resolution (25 km) version of the GEOS-Chem atmospheric transport model and an ensemble Kalman filter. We will present our current best estimate for CO2 fluxes and a preliminary assessment of the efficacy of individual GAUGE data sources to spatially resolve CO2 flux estimates over the UK. We will also discuss how flux estimates inferred from the different models used within GAUGE can help to assess the role of transport model error and to determine an ensemble CO2 flux estimate for the UK.

  15. Cycling to work in London and inhaled dose of black carbon.

    PubMed

    Nwokoro, Chinedu; Ewin, Clare; Harrison, Clare; Ibrahim, Mubin; Dundas, Isobel; Dickson, Iain; Mushtaq, Naseem; Grigg, Jonathan

    2012-11-01

    Modelling studies suggest that urban cycling is associated with an increased inhaled dose of fossil fuel-derived black carbon (BC). Using the amount of black material in airway macrophages as a marker of long-term inhaled BC, we sought to compare inhaled BC dose in London (UK) cyclists and non-cyclists. Airway macrophage carbon was assessed in 28 (58%) out of 48 healthy adults (14 cyclists and 14 non-cyclists) who attended for induced sputum. Short-term (24 h) exposure to BC was assessed on a representative working day in 27 out of 28 subjects. Serum interleukin (IL)-1β, IL-2, IL-6, IL-8, granulocyte-macrophage colony-stimulating factor and tumour necrosis factor (TNF)-α were assessed in 26 out of the 28 subjects. Cyclists were found to have increased airway macrophage carbon when compared with non-cyclists (mean ± se 1.81 ± 0.21 versus 1.11 ± 0.07 μm(2); p<0.01). Short-term monitoring showed no difference in 24 h BC exposure between the two groups. However, cyclists were exposed to higher concentrations of BC during commuting (p<0.01). Airway macrophage carbon was associated with monitored commute BC (n=28; r=0.47, p<0.05). TNF-α was found to be increased in cyclists (p<0.05), but no other cytokines were increased. Commuting to work by bicycle in London is associated with increased long-term inhaled dose of BC. Whether cycling per se increases inhaled BC dose remains unclear.

  16. UK national re-audit of sexual history-taking.

    PubMed

    Sullivan, A K; McClean, H; Carne, C A; Tayal, S; Daniels, D

    2012-03-01

    A focused repeat national audit of sexual history-taking was conducted in genitourinary (GU) medicine clinics in the UK in 2010, addressing several areas of practice under-performance identified in the baseline 2008 national audit. The case-notes of 4285 patients were audited. An increase in documentation was observed for all measures, except legibility which was unchanged. Despite the overall improvement, several measures (chaperone offer, condom usage and four of five aspects of HIV risk assessment) remained below target.

  17. Currently available medical engineering degrees in the UK. Part 1: Undergraduate degrees.

    PubMed

    Joyce, T

    2009-05-01

    This paper reviews mechanical-engineering-based medical engineering degrees which are currently provided at undergraduate level in the UK. At present there are 14 undergraduate degree programmes in medical engineering, offered by the University of Bath, University of Birmingham, University of Bradford, Cardiff University, University of Hull, Imperial College London, University of Leeds, University of Nottingham, University of Oxford, Queen Mary University of London, University of Sheffield, University of Southampton, University of Surrey, and Swansea University. All these undergraduate courses are delivered on a full-time basis, both 3 year BEng and 4 year MEng degrees. Half of the 14 degree courses share a core first 2 years with a mechanical engineering stream. The other seven programmes include medical engineering modules earlier in their degrees. Within the courses, a very wide range of medical-engineering-related modules are offered, although more common modules include biomaterials, biomechanics, and anatomy and physiology.

  18. Speeches to mark the accession of the UK to ESO: Lord Sainsbury, Arno Freytag, Catherine Cesarsky

    NASA Astrophysics Data System (ADS)

    2002-09-01

    To mark the occasion of the the tenth member state joining ESO, the UK invited ESO to hold its 98th Council meeting in London on 8-9 July 2002. The hosts provided a wonderful venue for the meeting in Trinity House, overlooking the Tower of London. An excursion to the historic Greenwich Observatory and a banquet at Lancaster House helped to make it an especially memorable occasion. A landmark decision made at the meeting was the approval for the construction and operation of the Atacama Large Millimeter Array (ALMA). The speeches given at the banquet by Lord Sainsbury, A. Freytag and C. Cesarsky are printed below, followed by an article by Prof. Gerry Gilmore on the British astronomers' perspective.

  19. An observational study of retail availability and in-store marketing of e-cigarettes in London: potential to undermine recent tobacco control gains?

    PubMed Central

    Hsu, Robert; Myers, Allison E; Ribisl, Kurt M; Marteau, Theresa M

    2013-01-01

    Objectives E-cigarette companies and vendors claim the potential of e-cigarettes to help smokers reduce or quit tobacco use. E-cigarettes also have the potential to renormalise smoking. The purpose of this study was to describe the availability and in-store marketing of e-cigarettes in London, UK stores selling tobacco and alcohol. Design Observational study. Setting Small and large stores selling alcohol and tobacco in London, UK. Primary and secondary outcome measures The number of stores selling e-cigarettes, the number of stores with an interior or exterior e-cigarette advertisement, the number of stores with an e-cigarette point-of-sale movable display, store size, deprivation index score for store's corresponding lower super output area. Results Audits were completed in 108 of 128 selected stores. 62 of the audited stores (57%) sold e-cigarettes. E-cigarette availability was unrelated to store size. There was a statistically non-significant trend towards increased availability in more deprived areas (p=0.069). 31 of the 62 stores (50%) selling e-cigarettes had a point-of-sale movable display, with all but one found in small stores. Two small stores had interior advertisements and eight had exterior advertisements. No advertisements were observed in large stores. Conclusions This audit revealed widespread availability of e-cigarettes and in-store marketing in London, UK. Even if e-cigarettes prove to be an effective cessation aid, their sale and use are resulting in an increasing public presence of cigarette-like images and smoking behaviour. After decades of work to denormalise smoking, these findings raise the question of whether e-cigarettes are renormalising smoking. PMID:24366581

  20. Multifractal to monofractal evolution of the London street network

    NASA Astrophysics Data System (ADS)

    Murcio, Roberto; Masucci, A. Paolo; Arcaute, Elsa; Batty, Michael

    2015-12-01

    We perform a multifractal analysis of the evolution of London's street network from 1786 to 2010. First, we show that a single fractal dimension, commonly associated with the morphological description of cities, does not suffice to capture the dynamics of the system. Instead, for a proper characterization of such a dynamics, the multifractal spectrum needs to be considered. Our analysis reveals that London evolves from an inhomogeneous fractal structure, which can be described in terms of a multifractal, to a homogeneous one, which converges to monofractality. We argue that London's multifractal to monofractal evolution might be a special outcome of the constraint imposed on its growth by a green belt. Through a series of simulations, we show that multifractal objects, constructed through diffusion limited aggregation, evolve toward monofractality if their growth is constrained by a nonpermeable boundary.

  1. Cosmopolitanism, geographical imaginaries and belonging in North London.

    PubMed

    Devadason, Ranji

    2010-01-01

    Cosmopolitanism has been described as the cultural habitus of globalisation. It is therefore, albeit defined somewhat loosely, often associated with ethnically diverse, global cities. This paper considers the extent to which London engenders cosmopolitan values amongst its residents. It draws on survey data from the LOCAL MULTIDEM study of minorities' political participation to address these themes. The analysis examines perceptions of respect, belonging and geographical imaginaries - amongst established minorities and the ethnic majority - in north London. It is argued that cosmopolitan ethics are transformative and dialectical and, critically, cannot remain the preserve of the privileged in multi-ethnic neighbourhoods. The analysis presented demonstrates that a sense of belonging and cosmopolitan imaginaries are not evenly accessed by different ethnic groups; notably, that Bangladeshi Londoners who are born and bred in the city are less likely to appropriate these discourses than Caribbean, Indian or White residents.

  2. The epidemiology of suicide on the London Underground.

    PubMed

    O'Donnell, I; Farmer, R D

    1994-02-01

    A database containing details of every incident of suicidal behaviour on the London Underground railway system between 1940 and 1990 was assembled from the records of London Underground Ltd and the British Transport Police. The total number of cases was 3240. The mean annual number of suicidal acts on the London Underground system increased from 36.1 (1940-1949) to 94.1 (1980-1989). There were significantly fewer incidents on Sundays than on the other days of the week and the daily rate was highest in the spring. 64% of incidents involved males and the peak age group for both sexes was 25-34 yr. Suicide verdicts were returned for a greater proportion of women than men. Overall case fatality was 55%. However, case fatality rates differed between stations, environmental factors appearing to influence survival. Possible strategies to prevent railway suicides and reduce the lethality of this method are discussed.

  3. Chemical composition and sources of organic aerosols over London from the ClearfLo 2012 campaigns

    NASA Astrophysics Data System (ADS)

    Finessi, Emanuela; Holmes, Rachel; Hopkins, James; Lee, James; Harrison, Roy; Hamilton, Jacqueline

    2014-05-01

    Air quality in urban areas represents a major public health issue with around one third of the European population concentrated in cities and numbers expected to increase at global scale, particularly in developing countries. Particulate matter (PM) represents a primary threat for human health as numerous studies have confirmed the association between increased levels of cardiovascular and respiratory diseases with the exposure to PM. Despite considerable efforts made in improving air quality and progressively stricter emissions regulations, the PM concentrations have not changed much over the past decades for reasons that remain unclear, and highlight that studies on PM source apportionment are required for the formulation of effective policy. We investigated the chemical composition of organic aerosol (OA) collected during two intensive field campaigns held in winter and summer 2012 in the frame of the project Clean air for London (http://www.clearflo.ac.uk/). PM samples were collected both at a city background site (North Kensington) and at a rural site 50 km southeast of London (Detling) with 8 to 24 hours sampling schedule and analysed using off-line methods. Thermal-optical analysis was used to quantify OC-EC components while a suite of soft ionization mass spectrometric techniques was deployed for detailed chemical characterization. Liquid chromatography mass Spectrometry (LC-MSn) was mostly used for the simultaneous detection and quantification of various tracers for both primary and secondary OA sources. Well-established markers for wood burning primary OA like levoglucosan and azelaic acid were quantified together with various classes of nitroaromatics including methyl-nitrocatechols that are potential tracers for wood burning secondary OA. In addition, oxidation products of biogenic VOCs such as isoprene and monoterpenes were also quantified for both seasons and sites. A non-negligible contribution from biogenic SOA to urban OA was found in summertime

  4. Investigating the annual behaviour of submicron secondary inorganic and organic aerosols in London

    NASA Astrophysics Data System (ADS)

    Young, D. E.; Allan, J. D.; Williams, P. I.; Green, D. C.; Flynn, M. J.; Harrison, R. M.; Yin, J.; Gallagher, M. W.; Coe, H.

    2015-06-01

    For the first time, the behaviour of non-refractory inorganic and organic submicron particulate through an entire annual cycle is investigated using measurements from an Aerodyne compact time-of-flight aerosol mass spectrometer (cToF-AMS) located at a UK urban background site in North Kensington, London. We show that secondary aerosols account for a significant fraction of the submicron aerosol burden and that high concentration events are governed by different factors depending on season. Furthermore, we demonstrate that on an annual basis there is no variability in the extent of secondary organic aerosol (SOA) oxidation, as defined by the oxygen content, irrespective of amount. This result is surprising given the changes in precursor emissions and contributions as well as photochemical activity throughout the year; however it may make the characterisation of SOA in urban environments more straightforward than previously supposed. Organic species, nitrate, sulphate, ammonium, and chloride were measured during 2012 with average concentrations (±1 standard deviation) of 4.32 (±4.42), 2.74 (±5.00), 1.39 (±1.34), 1.30 (±1.52), and 0.15 (±0.24) μg m-3, contributing 44, 28, 14, 13, and 2 % to the total non-refractory submicron mass (NR-PM1) respectively. Components of the organic aerosol fraction are determined using positive matrix factorisation (PMF), in which five factors are identified and attributed as hydrocarbon-like OA (HOA), cooking OA (COA), solid fuel OA (SFOA), type 1 oxygenated OA (OOA1), and type 2 oxygenated OA (OOA2). OOA1 and OOA2 represent more and less oxygenated OA with average concentrations of 1.27 (±1.49) and 0.14 (±0.29) μg m-3 respectively, where OOA1 dominates the SOA fraction (90%). Diurnal, monthly, and seasonal trends are observed in all organic and inorganic species due to meteorological conditions, specific nature of the aerosols, and availability of precursors. Regional and transboundary pollution as well as other individual

  5. Investigating the annual behaviour of submicron secondary inorganic and organic aerosols in London

    NASA Astrophysics Data System (ADS)

    Young, D. E.; Allan, J. D.; Williams, P. I.; Green, D. C.; Flynn, M. J.; Harrison, R. M.; Yin, J.; Gallagher, M. W.; Coe, H.

    2014-07-01

    For the first time, the behaviour of non-refractory inorganic and organic submicron particulate through an entire annual cycle is investigated using measurements from an Aerodyne compact time-of-flight aerosol mass spectrometer (cToF-AMS) located at a UK urban background site in North Kensington, London. We show secondary aerosols account for a significant fraction of the submicron aerosol burden and that high concentration events are governed by different factors depending on season. Furthermore, we demonstrate that on an annual basis there is no variability in the extent of secondary organic aerosol (SOA) oxidation, as defined by the oxygen content, irrespective of amount. This result is surprising given the changes in precursor emissions and contributions as well as photochemical activity throughout the year; however it may make the characterisation of SOA in urban environments more straightforward than previously supposed. Organic species, nitrate, sulphate, ammonium, and chloride were measured during 2012 with average concentrations (±one standard deviation) of 4.32 (±4.42), 2.74 (±5.00), 1.39 (±1.34), 1.30 (±1.52) and 0.15 (±0.24) μg m-3, contributing 43, 28, 14, 13 and 2% to the total submicron mass, respectively. Components of the organic aerosol fraction are determined using positive matrix factorisation (PMF) where five factors are identified and attributed as hydrocarbon-like OA (HOA), cooking OA (COA), solid fuel OA (SFOA), type 1 oxygenated OA (OOA1), and type 2 oxygenated OA (OOA2). OOA1 and OOA2 represent more and less oxygenated OA with average concentrations of 1.27 (±1.49) and 0.14 (±0.29) μg m-3, respectively, where OOA1 dominates the SOA fraction (90%). Diurnal, monthly, and seasonal trends are observed in all organic and inorganic species, due to meteorological conditions, specific nature of the aerosols, and availability of precursors. Regional and transboundary pollution as well as other individual pollution events influence London

  6. UK neonatal intensive care services in 1996

    PubMed Central

    Tucker, J.; Tarnow-Mordi, W.; Gould, C.; Parry, G.; Marlow, N.

    1999-01-01

    A census of activity and staff levels in 1996 was conducted in UK neonatal units and achieved a 100% response from 246 units. Among the 186 neonatal intensive care units, the median (interquartile range) number of total cots was 18(14−22); level 1 intensive care cots 4(2−6); total admissions 318(262−405); very low birthweight admissions 40(28−68); and the number ventilated or given CPAP by endotracheal tube 52(32−83). Forty six (25%) intensive care units lacked the recommended minimum of one consultant with prime responsibility for neonatal medicine. As a conservative estimate 79% of intensive care units had a lower nursing provision than that recommended in previously published guidelines. There was substantial variation in activity and staffing levels among units.

 PMID:10212089

  7. Communicating geohazard information for emergency responders, a case study from the UK.

    NASA Astrophysics Data System (ADS)

    Banks, Vanessa; Cooper, Anthony

    2016-04-01

    SSS11.4/ESSI4.6/HS11.39/NH9.13 Communication of uncertain information in earth sciences: data, models and visualization Communicating geohazard information for emergency responders, a case study from the UK. Cooper, A. H.1, Banks, V.J.1, Cowup, P.2, Curness, J.3, Davis, R.4, Dawson, L3. and Gazzard, L.4 1 British Geological Survey, Keyworth, NG12 5GG, UK 2 London Fire Brigade, 169 Union Street, London, SE1 0LL, UK 3.Coventry University, Priory Street, Coventry, CV1 5FB, UK 4.Avon Fire and Rescue, Temple Back, Bristol, BS1 6EU, UK. In February 2013 a sinkhole opened beneath a Florida Home resulting in the loss of a life and demolition of the affected home. The resulting void was in the order of 15 m deep. Neighbouring homes also had to be demolished. Television footage of this unfortunate incident resonated with an Assistant Commissioner of the London Fire Brigade who questioned whether or not such a feature would be recognised in the UK and if so, how the emergency response would be managed. Stemming from this, the British Geological Survey was invited to work with the Chief Fire Officers Association Urban Search and Rescue working group on geohazards. The aim of this group was to develop national tactical operational guidance on geohazards that would form the basis for regional guidance and training. The project was addressed collaboratively providing opportunities for two students from the Coventry University Disaster Management course, that were on placements with Avon Fire and Rescue, to work with the BGS to develop the guidance. Key to the success of the project was an iterative approach to knowledge exchange with respect to firstly, the characterization of the geohazards, and the processes and uncertainties associated with them and secondly, with respect to emergency responders' needs and priorities. Effective communication was achieved through challenging and rationalising the geoscience language for the end user and through a series of customised

  8. The management for tuberculosis control in Greater London in comparison with that in Osaka City: lessons for improvement of TB control management in Osaka City urban setting.

    PubMed

    Ohkado, Akihiro; Williams, Gini; Ishikawa, Nobukatsu; Shimouchi, Akira; Simon, Carter

    2005-07-01

    The tuberculosis (TB) notification in Osaka City has been persistently high compared with other urban areas in Japan. Although the TB notification in Greater London has kept much lower level compared with that in Osaka City, it has been also persistently high compared with other urban areas in the UK. Nonetheless, the contexts of the two cities relating TB control programme as well as the epidemiological situation greatly vary; there must be some lessons to be learnt from each other to improve each TB control programme to tackle against TB more effectively. Comparing the epidemiological situation of TB in both cities, it is obvious that Osaka City suffers TB more than Greater London in terms of the TB notification rate. Concerning the context of the TB control programme, Osaka City has centralised approach with strong local government commitment; Greater London, on the other hand, has an approach that is greatly fragmented but coordinated through voluntary TB Networks. This paper aims to draw some constructive and practical lessons from Greater London TB control management for further improvement of Osaka City TB control management through literature review and interview to health professionals. TB epidemiology in Greater London shows distinct features in the extent of TB in new entrants and TB co-infected with HIV in comparison with those in Osaka City. TB epidemiology in Osaka City is to a great extent specifically related to homeless people whereas in Greater London, this relationship occurs to a lesser extent. Both areas have relatively high TB-notification rates compared with national figures, and they have "TB hot spots" where remarkably high TB-notification rates exist. TB control in Greater London is characterised with decentralised and devolved services to local government health authorities supplemented with co-ordinating bodies across sectors as well as across Greater London. Sector-wide TB Network as well as London TB Group (LTBG) and London TB Nurses

  9. UK businesses bag innovation awards

    NASA Astrophysics Data System (ADS)

    Banks, Michael

    2015-09-01

    Five UK firms have received innovation awards from the Institute of Physics (IOP), which publishes Physics World. Hallmarq Veterinary Imaging, Metrasens, M Squared Lasers, Silixa and Tracerco have all won an IOP award for developing new innovative products.

  10. UK to support open access

    NASA Astrophysics Data System (ADS)

    Banks, Michael

    2012-08-01

    The UK government has "widely accepted" the recommendations of a major report into open-access publishing that was released in June by a 15-strong working group led by the British sociologist Janet Finch.

  11. Sources and contributions of wood smoke during winter in London

    NASA Astrophysics Data System (ADS)

    Crilley, Leigh; Bloss, William; Yin, Jianxin; Beddows, David; Harrison, Roy; Zotter, Peter; Prevot, Andre; Green, David

    2014-05-01

    Determining the contribution of wood smoke in large urban centres such as London is becoming increasingly important with the changing nature of domestic heating partly due to the installation of biomass burning heaters to meet renewable energy targets imposed by the EU and also a rise in so-called recreational burning for aesthetic reasons (Fuller et al., 2013). Recent work in large urban centres (London, Paris and Berlin) has demonstrated an increase in the contribution of wood smoke to ambient particles during winter that can at times exceed traffic emissions. In Europe, biomass burning has been identified as a major cause of exceedances of European air quality limits during winter (Fuller et al., 2013). In light of the changing nature of emissions in urban areas there is a need for on-going measurements to assess the impact of biomass burning in cities like London. Therefore we aimed to determine quantitatively the contribution of biomass burning in London and surrounding rural areas. We also aimed to determine whether local emissions or regional sources were the main source of biomass burning in London. Sources of wood smoke during winter in London were investigated at an urban background site (North Kensington) and two surrounding rural sites (Harwell and Detling) by analysing selected wood smoke chemical tracers. Concentrations of levoglucosan, elemental carbon (EC), organic carbon (OC) and K+ were generally well correlated, indicating a similar source of these species at the three sites. Based on the conversion factor for levoglucosan, mean wood smoke mass at Detling, North Kensington and Harwell was 0.78, 0.87 and 1.0 µg m-3, respectively. At all the sites, biomass burning was found to be a source of OC and EC, with the largest source of OC and EC found to be secondary organic aerosols and traffic emissions, respectively. Peaks in levoglucosan concentrations at the sites were observed to coincide with low ambient temperature, suggesting domestic heating as

  12. Determinants of clinician adoption of regenerative therapies in the UK and Canada: an ophthalmology perspective.

    PubMed

    Rose, James B; May, Michael; Williams, David J

    2015-05-01

    The determinants of adoption of regenerative medicine therapies are currently poorly understood. This study aims to draw comparison between the UK and Canada in terms of factors likely to affect healthcare adoption of future regenerative therapies in ophthalmology. Conducting semi-structured interviews with senior ophthalmologists in the UK and Canada, their perceptions of factors either enabling or limiting adoption were recorded and analyzed. A number of key concepts were extracted from the interview data, perceived by stakeholders to contribute to adoption. The core factors developed in this work will be of use to those looking to understand the opportunities and risks involved in securing clinician adoption in both the UK and Canada.

  13. "Persons That Live Remote from London": Apothecaries and the Medical Marketplace in Seventeenth-and Eighteenth-Century Wales

    PubMed Central

    Withey, Alun

    2011-01-01

    Summary This article uses evidence from Welsh apothecary shops as a means to access the mechanisms of the "medical marketplace" in seventeenth- and eighteenth-century Wales. As a country physically remote from large urban medical centers, and with few large towns, Wales has often been overlooked in terms of medical commerce. Nevertheless, evidence suggests that Welsh apothecaries participated in broad and sophisticated networks of trade with London suppliers. Moreover, their shops contained a wide range of medicines from herbal simples to exotic ingredients and chemical preparations, highlighting the availability of such goods far from large urban centers. PMID:21804184

  14. Biomedical practices from a patient perspective. Experiences of Polish female migrants in Barcelona, Berlin and London.

    PubMed

    Main, Izabella

    2016-08-01

    This paper focuses on the diversity in patients' experience of bio-medicine and contrasts it with the normative view characteristic of health professionals. Ethnographic fieldwork among Polish migrant women in London, Barcelona and Berlin included interviews about their experiences with local healthcare and health professionals. Themes drawn from the narratives are differences between the cities in terms of communication between patients and health professionals, respect for patients' choices and dignity, attitudes to pregnancy and birth (different levels of medicalization), and paediatric care. It is argued that patients continuously negotiate among their own views and expectations based on previous experiences and knowledge from personal communication; internet forums and publications; and the offer of medical services in the countries of their settlement. Patients experience pluralism of therapeutic traditions within and outside bio-medicine. In turn, representatives of bio-medicine are rarely aware of other medical practices and beliefs and this leads to various misunderstandings. By highlighting the pluralism of medical practices in European countries and the increasing mobility of patients, this case study has useful implications for medical anthropologists and health professionals in a broader Western context, such as raising sensitivity to different communication strategies and a diversity of curing traditions and expectations.

  15. Investigating public space exploration support in the UK

    NASA Astrophysics Data System (ADS)

    Entradas, Marta; Miller, Steve

    2010-10-01

    Space agencies such as NASA and ESA have ambitious long-term programmes that mark the beginning of a new era in space exploration where humans will land on Mars; an era requiring public support and, therefore, more consideration for public opinion. Empirical research shows that there are substantial differences in the level of understanding of space exploration among the general public. Studying audiences appears to be crucial to inform public engagement and communication strategies as well as policy debate. This paper presents the results of a survey conducted in the UK in 2008 at two science outreach events, the Royal Society Exhibition in London and the National Space Centre in Leicester, to investigate the motivations, beliefs, political preferences and attitudes towards space exploration of this audience. A sample of 744 respondents was collected. The analysis shows that the British public who come to outreach and engagement activities support space exploration but have some reservations about considering the advancement of UK space activities to be of national interest. Yet, when asked about means of exploring space, the majority agrees that space should be explored using both mankind and machines, ranking "generating new scientific knowledge and advancing human culture" as the most important reason for continuing investment in space research. Although the greater number of supporters says that more than the current government funding should be allocated to civil space activities, concerns about risk and value appear to influence this view.

  16. Diabetes Medicines

    MedlinePlus

    ... Problems Diabetes & Sexual & Urologic Problems Insulin, Medicines, & Other Diabetes Treatments Taking insulin or other diabetes medicines is ... also available. What medicines might I take for diabetes? The medicine you take will vary by your ...

  17. In-Street Wind Direction Variability in the Vicinity of a Busy Intersection in Central London

    NASA Astrophysics Data System (ADS)

    Balogun, Ahmed A.; Tomlin, Alison S.; Wood, Curtis R.; Barlow, Janet F.; Belcher, Stephen E.; Smalley, Robert J.; Lingard, Justin J. N.; Arnold, Sam J.; Dobre, Adrian; Robins, Alan G.; Martin, Damien; Shallcross, Dudley E.

    2010-09-01

    We present results from fast-response wind measurements within and above a busy intersection between two street canyons (Marylebone Road and Gloucester Place) in Westminster, London taken as part of the DAPPLE (Dispersion of Air Pollution and Penetration into the Local Environment; www.dapple.org.uk uk" TargetType="URL"/> ) 2007 field campaign. The data reported here were collected using ultrasonic anemometers on the roof-top of a building adjacent to the intersection and at two heights on a pair of lamp-posts on opposite sides of the intersection. Site characteristics, data analysis and the variation of intersection flow with the above-roof wind direction ( θ ref ) are discussed. Evidence of both flow channelling and recirculation was identified within the canyon, only a few metres from the intersection for along-street and across-street roof-top winds respectively. Results also indicate that for oblique roof-top flows, the intersection flow is a complex combination of bifurcated channelled flows, recirculation and corner vortices. Asymmetries in local building geometry around the intersection and small changes in the background wind direction (changes in 15- min mean θ ref of 5°-10°) were also observed to have profound influences on the behaviour of intersection flow patterns. Consequently, short time-scale variability in the background flow direction can lead to highly scattered in-street mean flow angles masking the true multi-modal features of the flow and thus further complicating modelling challenges.

  18. Connecting Londoners with Their City through Digital Technologies

    ERIC Educational Resources Information Center

    Swift, Frazer

    2013-01-01

    London is one of the most complex, dynamic and diverse cities in the world, with 8 million residents, over 300 languages spoken in its schools, and some 30 million overseas visitors every year. Reaching out to and connecting all these people with the city's heritage while catering to their many interests, motivations and learning needs is a huge…

  19. Battersea: Education in a London Parish since 1750

    ERIC Educational Resources Information Center

    Saint, Andrew

    2010-01-01

    This paper examines the development of educational institutions and buildings in one slice of a big city over a long timescale. The city is London and the slice Battersea, an inner suburb of mixed character and volatile fortunes. The narrative explores the shifts and interactions between state and voluntary provision, local community needs and…

  20. The London Lighthouse. A centre for people with AIDS.

    PubMed

    1988-12-01

    In October last year an Evian Health Award was presented to Mr Christopher Spence, director of London Lighthouse, for pioneering the first independent aids hospice against much opposition. The Lighthouse is now open and although the hospice is the core of its work it also provides a range of other services.

  1. A fatal case of Lassa fever in London, January 2009.

    PubMed

    Kitching, A; Addiman, S; Cathcart, S; Bischop, L; Krahé, D; Nicholas, M; Coakley, J; Lloyd, G; Brooks, T; Morgan, D; Turbitt, D

    2009-02-12

    In January 2009, the eleventh [corrected] case of Lassa fever imported to the United Kingdom was diagnosed in London. Risk assessment of 328 healthcare contacts with potential direct exposure to Lassa virus - through contact with the case or exposure to bodily fluids - was undertaken. No contacts were assessed to be at high risk of infection and no secondary clinical cases identified.

  2. Martha Whiteley of Imperial College, London: A Pioneering Woman Chemist

    ERIC Educational Resources Information Center

    Nicholson, Rafaelle M.; Nicholson, John W.

    2012-01-01

    Martha Whiteley (1866-1956) was one of the most important women chemists in the United Kingdom in the first half of the 20th century. In a male-dominated field, she was an academic on the staff of a co-educational university, Imperial College, London, where she carried out research of her own choosing, rather than assisting a male professor. She…

  3. Gender Politics and Privatization in the London Borough of Camden.

    ERIC Educational Resources Information Center

    Brush, Lisa D.

    1986-01-01

    This article examines the differential impact of the privatization of social services on women in the London borough of Camden. Concludes that women will suffer greater decline than men in employment, wages, and status as a result of the privatization taking place in Great Britain. (JDH)

  4. Multicultural Music in the London Borough of Harrow.

    ERIC Educational Resources Information Center

    Murphy, Frank

    1991-01-01

    A project to introduce the music of different cultures into primary and secondary classrooms in London is reported. The six cultures are Indian music and dance, Latin American rock and steel pans, jazz, Indian drums, and Chinese music and movement. The project model is related to multicultural education in general. (Author/LB)

  5. Autistic Disorder in Nineteenth-Century London. Three Case Reports

    ERIC Educational Resources Information Center

    Waltz, Mitzi; Shattock, Paul

    2004-01-01

    This article examines the existence, description, perception, treatment, and outcome of symptoms consistent with autistic disorder in nineteenth-century London, England, based on case histories from the notes of Dr William Howship Dickinson at Great Ormond Street Hospital for Children. Three cases meeting the DSM-IV criteria for autistic disorder…

  6. In London, a Working-Class University Wrestles with Change

    ERIC Educational Resources Information Center

    Labi, Aisha

    2012-01-01

    Patrick McGhee, vice chancellor of the University of East London, has a lot in common with many of the 28,000 students at the large urban institution he leads. He was the first in his family to attend university. And he dislikes much about the government's higher-education reform efforts, which he has deemed "misguided, premature, unproven…

  7. Intergenerational Learning between Children and Grandparents in East London

    ERIC Educational Resources Information Center

    Kenner, Charmian; Ruby, Mahera; Jessel, John; Gregory, Eve; Arju, Tahera

    2007-01-01

    This study investigates the learning exchange between three- to six-year-old children and their grandparents, in Sylheti/Bengali-speaking families of Bangladeshi origin and monolingual English-speaking families living in east London. The following concepts from sociocultural theory are applied to this new area of intergenerational learning:…

  8. The University College London Archive of Stuttered Speech (UCLASS)

    ERIC Educational Resources Information Center

    Howell, Peter; Davis, Stephen; Bartrip, Jon

    2009-01-01

    Purpose: This research note gives details of 2 releases of audio recordings available from speakers who stutter that can be accessed on the Web. Method: Most of the recordings are from school-age children. These are available on the University College London Archive of Stuttered Speech (UCLASS) Web site, and information is provided about how to…

  9. The social impact of dizziness in London and Siena.

    PubMed

    Bronstein, Adolfo M; Golding, John F; Gresty, Michael A; Mandalà, Marco; Nuti, Daniele; Shetye, Anu; Silove, Yvonne

    2010-02-01

    Although dizziness is a common presenting symptom in general and hospital practice, its social cost is not known. We assessed the social and work life impact of dizziness on patients in two contrasting European cities, Siena and London. First, we developed the 'Social life & Work Impact of Dizziness questionnaire' (SWID), which was validated by administering it to 43 patients with dizziness and 45 normal controls and by correlating the results with the EQ-5D (Europe quality of life) questionnaire. The SWID and EQ-5D scores were worse in patients than controls (p < 0.001) and the two correlated significantly (r = 0.50 p < 0.001). Then two hundred consecutive patients per city attending tertiary specialised 'dizzy patient' clinics, one in London led by a neurologist, one in Siena led by an ear, nose and throat specialist (ENT), were investigated with SWID. Amongst the 400 patients, 27% reported changing their jobs and 21% giving up work as a result of the dizziness. Over 50% of patients felt that their efficiency at work had dropped considerably. The mean number of days off work attributed to the dizziness in the previous 6 months was 7.15 days. Social life was disrupted in 57% of all 400 patients. Factor analysis identified that detrimental effects on work, travel, social and family life combine to create a single factor accounting for much of the overall impact of their dizziness. Significant differences in some measures of handicap between London and Siena emerged, with London patients often faring worse. Reasons for these location differences include, as expected, a higher proportion of neurological patients in London than in Siena. However, factors related to city demographics and social cohesion may also modulate the impact on quality of life and working practice. Regardless of inter-city differences, these findings highlight the high social and economic impact of dizziness.

  10. Ozone and Trace Gas Trends in the UK and Links to Changing Air Mass Pathways

    NASA Astrophysics Data System (ADS)

    Fleming, Z.; Monks, P. S.; Reeves, C.; Bohnenstengel, S.

    2014-12-01

    Trace gas measurements from UK measurement sites on the North Sea coast and in central London reveal a complicated relationship between NO2, CO, hydrocarbons and ozone. Due to the location of the sites, they receive air masses from the UK, Europe, the North sea, Scandinavia and the Arctic and Atlantic Seas and any seasonality is hard to discern. The transport pathway of air masses that can change on an hourly timescale clearly influences the trace gas levels. Investigations into how the transport pathways have changed over the years, using the NAME dispersion model try to elucidate whether it is the 'where' (transport pathway) or the 'what' (trace gas emissions) that is leading to the ozone trends recorded over the past few years.

  11. Key Barriers to Community Cohesion: Views from Residents of 20 London Deprived Neighbourhoods

    PubMed Central

    Bertotti, Marcello; Adams-Eaton, Faye; Sheridan, Kevin; Renton, Adrian

    2016-01-01

    The notion of community has been central to the political project of renewal of New Labour in the UK. The paper explores how the discourses of community are framed within New Labour and discusses these in the light of the results from research which focuses on how people within urban deprived areas construct their community. It draws upon the results of one part of a larger research project (the ‘Well London’ programme) which aimed to capture the views of residents from 20 disadvantaged neighbourhoods throughout London using an innovative qualitative method known as the ‘World Café’. Our results show the centrality of young people to the development of cohesive communities, the importance of building informal relationships between residents alongside encouraging greater participation to policy making, and the need to see these places as fragile and temporary locations but with considerable social strengths. Government policies are only partially addressing these issues. They pay greater attention to formally encouraging citizens to become more involved in policy making, largely ignore the contribution young people could make to the community cohesion agenda, and weakly define the shared norms and values that are crucial in building cohesive communities. Thus, the conclusion is that whilst an emphasis of the government on ‘community’ is to be welcome, more needs to be done in terms of considering the ‘voices’ of the community as well as enabling communities to determine and act upon their priorities. PMID:27761059

  12. Inequalities in the use of dental services among adults in inner South East London.

    PubMed

    Al-Haboubi, Mustafa; Klass, Charlotte; Jones, Kate; Bernabé, Eduardo; Gallagher, Jennifer E

    2013-06-01

    Improving access to National Health Service (NHS) dentistry is a public health issue that has been a focus for successive governments and policy makers in the UK. To inform this process, commissioners of services need to understand trends in service use and demands of the local population. This study explored inequalities in dental services use among adults in a socially deprived, ethnically diverse metropolitan area of London; satisfaction with services; and public views for improvement of services. Data from 695 adults were analysed for this study (56% of the eligible sample). Inequalities in dental services use and satisfaction with care according to sociodemographic factors were assessed in unadjusted and fully adjusted models. The proportion of participants who reported attending the dentist in the last 24 months was 69%, with inequalities according to social grade, ethnicity, sex and age but not according to borough of residence. The most common areas identified by respondents for service improvement were availability of dentists, affordability of care, and accommodation of services. Among those who visited the dentist in the last 24 months, 90% were satisfied with the quality of care provided. However, there were inequalities in satisfaction with care according to borough and reason for the last dental visit.

  13. Lessons from the syphilis outbreak in homosexual men in east London

    PubMed Central

    Hourihan, M; Wheeler, H; Houghton, R; Goh, B

    2004-01-01

    Objectives: To describe the epidemiology, presentation, and diagnosis of early syphilis in 103 homosexual men in east London. Methods: A retrospective study using data from KC60 returns, the Health Protection Agency (HPA) enhanced surveillance forms and case notes. Results: 40 cases of primary (PS), 40 of secondary (SS) and 23 of early latent syphilis were identified, 33% co-infected with HIV. 41% had concurrent sexually transmitted infections (STIs). Pain featured in 35% of PS and itch in 13% of rashes. Dark ground microscopy (DGM), performed in 44 of the symptomatic cases, was positive in 37 (84%) allowing early management. Initial syphilis serology was negative in 15/40 (37%) cases of PS. 51% and 49% opted for parenteral and oral treatment, respectively. In 53/103 (51%) cases oral sex was the only risk factor. 86% of infections were UK acquired. Only 4% of contacts were seen. Conclusion: This outbreak, reflecting the resurgence of syphilis across the United Kingdom, highlights several important points. Painful chancres and itchy rash are common presentations. DGM is a highly sensitive diagnostic tool. Initial negative serological screening tests are common in PS and sero-surveillance for 3 months is recommended. The high prevalence of concomitant STIs indicates ongoing unprotected sexual intercourse. Oral sex is a significant risk factor and is a distinctly "unsafe" practice. Conventional partner notification is ineffective. Other methods of screening of the at-risk homosexual population are warranted. Continued education is required to reduce STI acquisition in homosexual men. PMID:15572625

  14. Geographically varying associations between personality and life satisfaction in the London metropolitan area

    PubMed Central

    Jokela, Markus; Bleidorn, Wiebke; Lamb, Michael E.; Gosling, Samuel D.; Rentfrow, Peter J.

    2015-01-01

    Residential location is thought to influence people’s well-being, but different individuals may value residential areas differently. We examined how life satisfaction and personality traits are geographically distributed within the UK London metropolitan area, and how the strength of associations between personality traits and life satisfaction vary by residential location (i.e., personality–neighborhood interactions). Residential area was recorded at the level of postal districts (216 districts, n = 56,019 participants). Results indicated that the strength of associations between personality traits and life satisfaction depended on neighborhood characteristics. Higher openness to experience was more positively associated with life satisfaction in postal districts characterized by higher average openness to experience, population density, and ethnic diversity. Higher agreeableness and conscientiousness were more strongly associated with life satisfaction in postal districts with lower overall levels of life satisfaction. The associations of extraversion and emotional stability were not modified by neighborhood characteristics. These findings suggest that people’s life satisfaction depends, in part, on the interaction between individual personality and particular features of the places they live. PMID:25583480

  15. The diurnal cycle of the Urban Convective Boundary Layer over London

    NASA Astrophysics Data System (ADS)

    Halios, Christos; Barlow, Janet; Wood, Curtis

    2014-05-01

    The daily evolution of the Urban Convective Boundary Layer is of importance in terms of the dispersion of pollutants and for initializing models. In particular, morning and afternoon transition periods are of interest for initializing prognostic models and also for basic understanding of significant processes such as the nocturnal low level jet (LLJ) and the whole structure of the nocturnal atmospheric boundary layer. Moreover, significant differences in the diurnal cycle of fluxes and boundary layer depths of urban and rural sites are expected due to different surface energy balance observed in urban and rural areas. Yet, long term observations of fluxes and boundary layer depth at both urban and rural sites are rear. The aim of the present study is to examine the major phases (morning expansion, midday developed and afternoon decay) of the diurnal cycle of the Convective Boundary Layer. Towards this aim more than 1 year of measurements of a HALO Photonics Doppler Lidar and eddy covariance systems deployed in the frame of the ACTUAL (Advanced Climate Technology Urban Atmospheric Laboratory) project in central London, UK were analyzed. The urban lidar was operating in two modes: continuous stare mode (pointing vertically) and Doppler Beam Swinging (DBS) mode measuring the turbulence and the wind speed vertical profile respectively. The urban CBL is compared to the CBL over a nearby rural site (Chilbolton) and differences in urban and rural boundary layers are analyzed in terms of atmospheric stability and direction of the prevailing flow.

  16. London through Rose-Colored Graphics: Visual Rhetoric and Information Graphic Design in Charles Booth's Maps of London Poverty

    ERIC Educational Resources Information Center

    Kimball, Miles A.

    2006-01-01

    In this article, I examine a historical information graphic--Charles Booth's maps of London poverty (1889-1902)--to analyze the cultural basis of ideas of transparency and clarity in information graphics. I argue that Booth's maps derive their rhetorical power from contemporary visual culture as much as from their scientific authority. The visual…

  17. Audit of the job satisfaction levels of the UK radiography and physics workforce in UK radiotherapy centres 2012

    PubMed Central

    Beardmore, C; Patel, I; Massey, J; Wong, H; Probst, H

    2014-01-01

    Objective: Workforce planning reports identify a staff shortfall that jeopardizes the ability of UK radiotherapy centres to meet future demands. Obtaining an understanding of the work experiences of radiotherapy professionals will support the development of strategies to increase job satisfaction, productivity and effectiveness. Methods: A quantitative survey assessed job satisfaction, attitudes to incident reporting, stress and burnout, opportunities for professional development, workload, retention and turnover. Clinical oncologists were not included, as the Royal College of Radiologists, London, UK, had recently assessed their members' satisfaction. All questions were taken from validated instruments or adapted from the “UK National Health Service Staff Survey”. Results: The survey yielded 658 completed responses (approximately 16% response rate), from public and private sectors. Over a third (36%) of respondents were classified as satisfied for job satisfaction with 11% dissatisfied and the remaining 53% ambivalent. A significant proportion of clinical staff (37.5%) report high emotional exhaustion. Presenteeism was an issue with 42.4% attending work despite feeling unable to fulfil their role. Conclusion: Radiotherapy professionals are prone to the effects of compassion fatigue and burnout. Attention must be paid to workload and its impact on practitioners' job satisfaction. Professional development that is supported and informed by a performance development review is a simple and effective means of enhancing satisfaction. Individuals have a responsibility to themselves and their colleagues as their behaviours and attitudes influence job satisfaction. Advances in knowledge: This work identifies areas for future research to enhance the professional resilience of practitioners, in order to provide high-quality treatments. PMID:24786316

  18. Inner London's Education Authority: Reflections on ILEA Twenty-Five Years after Closure

    ERIC Educational Resources Information Center

    Mitchell, Peter

    2015-01-01

    It is 25 years since the Inner London Education Authority (ILEA) was abolished and management of education in central London transferred to 13 London boroughs. The author reflects on the experience of being an ex-ILEA head teacher, and of managing one of the new local education authorities in the immediate post-ILEA period. He begins by commenting…

  19. Building a Hypertextual Digital Library in the Humanities: A Case Study on London.

    ERIC Educational Resources Information Center

    Crane, Gregory; Smith, David A.; Wulfman, Clifford E.

    This paper describes the creation of a new humanities digital library collection: 11,000,000 words and 10,000 images representing books, images, and maps on pre-twentieth century London and its environs. The London collection contained far more dense and precise information than the materials from the Greco-Roman world. The London collection thus…

  20. Mutual learning and research messages: India, UK, and Europe

    PubMed Central

    Kalra, Gurvinder; Bhugra, Dinesh

    2010-01-01

    India and UK have had a long history together, since the times of the British Raj. Most of what Indian psychiatry is today, finds its roots in ancient Indian texts and medicine systems as much as it is influenced by the European system. Psychiatric research in India is growing. It is being influenced by research in the UK and Europe and is influencing them at the same time. In addition to the sharing of ideas and the know-how, there has also been a good amount of sharing of mental health professionals and research samples in the form of immigrants from India to the UK. The Indian mental health professionals based in UK have done a good amount of research with a focus on these Indian immigrants, giving an insight into cross-cultural aspects of some major psychiatric disorders. This article discusses the impact that research in these countries has had on each other and the contributions that have resulted from it. PMID:21836716

  1. Education in the attic: an insight into the educational services of the Old Operating Theatre Museum and Herb Garret, London Bridge.

    PubMed

    Edge, Stevie

    2009-01-01

    Hidden for almost a century in the attic of St Thomas' Church the oldest operating theatre in Britain is now part of a museum. This precious building now houses a collection of pre-anaesthetic tools, items relating to medicine in the home and various Apothecary displays. The museum aims to preserve the theatre and items relating to medicine, in order to contribute to the understanding of the development of medical knowledge, with particular reference to St Thomas' hospital. An independent museum with a long history of educational provision: this article explores some of the education services of The Old Operating Theatre Museum and Herb Garret at London Bridge.

  2. The sexual attitudes and lifestyles of London's Eastern Europeans (SALLEE Project): design and methods

    PubMed Central

    2009-01-01

    Background Since May 2004, ten Central and Eastern European (CEE) countries have joined the European Union, leading to a large influx of CEE migrants to the United Kingdom (UK). The SALLEE project (sexual attitudes and lifestyles of London's Eastern Europeans) set out to establish an understanding of the sexual lifestyles and reproductive health risks of CEE migrants. CEE nationals make up a small minority of the population resident in the UK with no sampling frame from which to select a probability sample. There is also difficulty estimating the socio-demographic and geographical distribution of the population. In addition, measuring self-reported sexual behaviour which is generally found to be problematic, may be compounded among people from a range of different cultural and linguistic backgrounds. This paper will describe the methods adopted by the SALLEE project to address these challenges. Methods The research was undertaken using quantitative and qualitative methods: a cross-sectional survey of CEE migrants based on three convenience samples (recruited from community venues, sexual health clinics and from the Internet) and semi-structured in-depth interviews with a purposively selected sample of CEE migrants. A detailed social mapping exercise of the CEE community was conducted prior to commencement of the survey to identify places where CEE migrants could be recruited. A total of 3,005 respondents took part in the cross-sectional survey, including 2,276 respondents in the community sample, 357 in the clinic sample and 372 in the Internet sample. 40 in-depth qualitative interviews were undertaken with a range of individuals, as determined by the interview quota matrix. Discussion The SALLEE project has benefited from using quantitative research to provide generalisable data on a range of variables and qualitative research to add in-depth understanding and interpretation. The social mapping exercise successfully located a large number of CEE migrants for the

  3. Anaesthesia and pre-hospital emergency medicine.

    PubMed

    Booth, A; Steel, A; Klein, J

    2013-01-01

    Major trauma is a leading cause of death and disability in the UK, particularly in the young. Pre-hospital emergency medicine (PHEM) involves provision of immediate medical care to critically ill and injured patients, across all age ranges, often in environments that may be remote and are not only physically challenging but also limited in terms of time and resources. PHEM is now a GMC-recognised subspecialty of anaesthesia or emergency medicine and the first recognised training program in the UK commenced in August 2012. This article discusses subspeciality development in PHEM, the competency based framework for training in PHEM, and the provision of pre-hospital emergency anaesthesia.

  4. Evolving Pb isotope signatures of London airborne particulate matter (PM 10)-constraints from on-filter and solution-mode MC-ICP-MS.

    PubMed

    Noble, Stephen R; Horstwood, Matthew S A; Davy, Pamela; Pashley, Vanessa; Spiro, Baruch; Smith, Steve

    2008-07-01

    Pb isotope compositions of biologically significant PM(10) atmospheric particulates from a busy roadside location in London UK were measured using solution- and laser ablation-mode MC-ICP-MS. The solution-mode data for PM(10) sampled between 1998-2001 document a dramatic shift to increasingly radiogenic compositions as leaded petrol was phased out. LA-MC-ICP-MS isotope analysis, piloted on a subset of the available samples, is shown to be a potential reconnaissance analytical technique. PM(10) particles trapped on quartz filters were liberated from the filter surface, without ablating the filter substrate, using a 266 nm UV laser and a dynamic, large diameter, low-fluence ablation protocol. The Pb isotope evolution noted in the London data set obtained by both analytical protocols is similar to that observed elsewhere in Western Europe following leaded petrol elimination. The data therefore provide important baseline isotope composition information useful for continued UK atmospheric monitoring through the early 21(st) century.

  5. Carrington-L5: The UK/US Operational Space Weather Monitoring Mission

    NASA Astrophysics Data System (ADS)

    Trichas, Markos; Gibbs, Mark; Harrison, Richard; Green, Lucie; Eastwood, Jonathan; Bentley, Bob; Bisi, Mario; Bogdanova, Yulia; Davies, Jackie; D'Arrigo, Paolo; Eyles, Chris; Fazakerley, Andrew; Hapgood, Mike; Jackson, David; Kataria, Dhiren; Monchieri, Emanuele; Windred, Phil

    2015-06-01

    Airbus Defence and Space (UK) has carried out a study to investigate the possibilities for an operational space weather mission, in collaboration with the Met Office, RAL, MSSL and Imperial College London. The study looked at the user requirements for an operational mission, a model instrument payload, and a mission/spacecraft concept. A particular focus is cost effectiveness and timelineness of the data, suitable for 24/7 operational forecasting needs. We have focussed on a mission at L5 assuming that a mission to L1 will already occur, on the basis that L5 (Earth trailing) offers the greatest benefit for the earliest possible warning on hazardous SWE events and the most accurate SWE predictions. The baseline payload has been selected to cover all UK Met Office/NOAA's users priorities for L5 using instruments with extensive UK/US heritage, consisting of: heliospheric imager, coronograph, magnetograph, magnetometer, solar wind analyser and radiation monitor. The platform and subsystems are based on extensive re-use from past Airbus Defence and Space spacecraft to minimize the development cost and a Falcon-9 launcher has been selected on the same basis. A schedule analysis shows that the earliest launch could be achieved by 2020, assuming Phase A kick-off in 2015-2016. The study team have selected the name "Carrington" for the mission, reflecting the UK's proud history in this domain.

  6. Carrington-L5: The UK/US Space Weather Operational Mission.

    NASA Astrophysics Data System (ADS)

    Bisi, M. M.; Trichas, M.

    2015-12-01

    Airbus Defence and Space (UK) have carried out a study for an operational L5 space weather mission, in collaboration with RAL, the UK Met Office, UCL and Imperial College London. The study looked at the user requirements for an operational mission, a model instrument payload, and a mission/spacecraft concept. A particular focus is cost effectiveness and timelineness of the data, suitable for operational forecasting needs. The study focussed on a mission at L5 assuming that a US mission to L1 will already occur, on the basis that L5 offers the greatest benefit for SWE predictions. The baseline payload has been selected to address all MOSWOC/SWPC priorities using UK/US instruments, consisting of: a heliospheric imager, coronagraph, EUV imager, magnetograph, magnetometer, solar wind analyser and radiation monitor. The platform is based on extensive re-use from Airbus' past missions to minimize the cost and a Falcon-9 launcher has been selected on the same basis. A schedule analysis shows that the earliest launch could occur in 2020, assuming Phase A KO in 2015. The study team have selected the name "Carrington" for the mission, reflecting the UK's proud history in this domain.

  7. Investigation of the emissions and profiles of a wide range of VOCs during the Clean air for London project

    NASA Astrophysics Data System (ADS)

    Holmes, Rachel; Lidster, Richard; Hamilton, Jacqueline; Lee, James; Hopkins, James; Whalley, Lisa; Lewis, Alistair

    2014-05-01

    The majority of the World's population live in polluted urbanized areas. Poor air quality is shortening life expectancy of people in the UK by an average 7-8 months and costs society around £20 billion per year.[1] Despite this, our understanding of atmospheric processing in urban environments and its effect on air quality is incomplete. Air quality models are used to predict how air quality changes given different concentrations of pollution precursors, such as volatile organic compounds (VOCs). The urban environment of megacities pose a unique challenge for air quality measurements and modelling, due to high population densities, pollution levels and complex infrastructure. For over 60 years the air quality in London has been monitored, however the existing measurements are limited to a small group of compounds. In order to fully understand the chemical and physical processes that occur in London, more intensive and comprehensive measurements should be made. The Clean air for London (ClearfLo) project was conducted to investigate the air quality, in particular the boundary layer pollution, of London. A relatively new technique, comprehensive two dimensional gas chromatography (GC×GC) [2] was combined with a well-established dual channel GC (DC-GC) [3] system to provide a more comprehensive measurement of VOCs. A total of 78 individual VOCs (36 aliphatics, 19 monoaromatics, 21 oxygenated and 2 halogenated) and 10 groups of VOCs (8 aliphatic, 1 monoaromatic and 1 monoterpene) from C1-C13+ were quantified. Seasonal and diurnal profiles of these VOCs have been found which show the influence of emission source and chemical processing. Including these extra VOCs should enhance the prediction capability of air quality models thus informing policy makers on how to potentially improve air quality in megacities. References 1. House of Commons Environmental Audit Committee, Air Quality: A follow-up report, Ninth Report of session 2012-12. 2. Lidster, R.T., J.F. Hamilton

  8. Teaching Astronomy in UK Schools

    ERIC Educational Resources Information Center

    Roche, Paul; Roberts, Sarah; Newsam, Andy; Barclay, Charles

    2012-01-01

    This article attempts to summarise the good, bad and (occasionally) ugly aspects of teaching astronomy in UK schools. It covers the most common problems reported by teachers when asked about covering the astronomy/space topics in school. Particular focus is given to the GCSE Astronomy qualification offered by Edexcel (which is currently the…

  9. Aerospace Medicine

    NASA Technical Reports Server (NTRS)

    Michaud, Vince

    2015-01-01

    NASA Aerospace Medicine overview - Aerospace Medicine is that specialty area of medicine concerned with the determination and maintenance of the health, safety, and performance of those who fly in the air or in space.

  10. Nuclear Medicine.

    ERIC Educational Resources Information Center

    Badawi, Ramsey D.

    2001-01-01

    Describes the use of nuclear medicine techniques in diagnosis and therapy. Describes instrumentation in diagnostic nuclear medicine and predicts future trends in nuclear medicine imaging technology. (Author/MM)

  11. 33 CFR 110.147 - New London Harbor, Conn.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    .... (4) Anchorage D. In Long Island Sound approximately two miles west-southwest of New London Ledge...,460 yards; 009°, 2,480 yards; 026°, 1,175 yards; and 008°, 1,075 yards. (3) Anchorage C. In the Thames... Ledge Light: 246°, 2.6 miles; 247°, 2.1 miles; 233°, 2.1 miles; and 235°, 2.6 miles. (5) Anchorage...

  12. 33 CFR 110.147 - New London Harbor, Conn.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... (4) Anchorage D. In Long Island Sound approximately two miles west-southwest of New London Ledge...,460 yards; 009°, 2,480 yards; 026°, 1,175 yards; and 008°, 1,075 yards. (3) Anchorage C. In the Thames... Ledge Light: 246°, 2.6 miles; 247°, 2.1 miles; 233°, 2.1 miles; and 235°, 2.6 miles. (5) Anchorage...

  13. Women's beliefs about medication use during their pregnancy: a UK perspective.

    PubMed

    Twigg, M J; Lupattelli, A; Nordeng, H

    2016-08-01

    Background Previous research has examined the number and extent of medicines taking in pregnant women but not their beliefs and risk perception surrounding their use. Objective To describe beliefs and risk perception associated with medicines use for the treatment of common acute conditions among UK women and explore whether this is related to actual medicines use. Settings Cross-sectional, web-based study in the UK. Methods Pregnant women and mothers within 1 year of giving birth were invited to participate in an online cross-sectional questionnaire-based study via a pregnancy website in the UK. Anonymous data were collected from women regarding their use of medicines (both over-the-counter and prescribed) and their beliefs regarding medicines use during pregnancy. Main outcome measures Pregnant women's beliefs about medicines and their relation to pharmacological treatment of acute conditions in pregnancy. Results Pharmacological treatment of conditions in pregnancy ranged from 65.4 % for urinary tract infections (UTIs) to 1.1 % for sleeping problems. Almost three out of ten women avoided using some medications during pregnancy. For heartburn and UTIs, women who did not treat the condition viewed medicines in general as being overused, more harmful and less beneficial, than those who treated the condition. In general, UK pregnant women perceived medicines to be beneficial and slightly overused. Conclusions Women's beliefs about medications impact on treatment of specific conditions in pregnancy such as heartburn and UTIs. Healthcare professionals should explore patient's beliefs regarding medication at the first maternity care visit to promote appropriate medication use in pregnancy.

  14. Millennium-long recession of limestone facades in London

    NASA Astrophysics Data System (ADS)

    Brimblecombe, Peter; Grossi, Carlota M.

    2008-12-01

    Historical data on the temperature and precipitation data for London has been combined with output from the Hadley Model to estimate the climate of London for the period 1100-2100 CE. This has been converted to other parameters such as freeze-thaw frequency and snowfall relevant to the weathering of stone facades. The pollutant concentrations have been estimated for the same period, with the historical values taken from single box modelling and future values from changes likely given current policy within the metropolis. These values are used in the Lipfert model to show that the recession from karst weathering dominates across the period, while the contributions of sulphur deposition seem notable only across a shorter period 1700-2000 CE. Observations of the late seventeenth century suggest London architects witnessed a notable increase in the recession rate and attributed “fretting quality” to “smoaks of the sea-coal”. The recession rates measured in the late twentieth century lend some support to the estimates from the Lipfert model. The recession looks to increase only slightly, and frost shattering will decrease while salt weathering is likely to increase.

  15. Trust, Autonomy and Relationships: The Help-Seeking Preferences of Young People in Secondary Level Schools in London (UK)

    ERIC Educational Resources Information Center

    Leavey, Gerard; Rothi, Despina; Paul, Rini

    2011-01-01

    Help-seeking among young people is complicated, often determined vicariously by the ability of adults, family or professionals, to recognize, and respond to, their difficulties. We know very little about the complex concerns of teenage young people and how they impact on help-seeking preferences. We aimed to ascertain the help-seeking preferences…

  16. Online Information 96. Proceedings of the International Online Information Meeting (20th, London, England, UK, December 3-5, 1996).

    ERIC Educational Resources Information Center

    Raitt, David I., Ed.; Jeapes, Ben, Ed.

    This proceedings volume contains 68 papers. Subjects addressed include: access to information; the future of information managers/librarians; intelligent agents; changing roles of library users; disintermediation; Internet review sites; World Wide Web (WWW) search engines; Java; online searching; future of online education; integrated information…

  17. Pharma Pricing & Market Access Europe 2016--Health Network Communications' Tenth Annual Conference (February 23-25, 2016--London, UK).

    PubMed

    D'Souza, P

    2016-03-01

    Tighter national budgets and escalating drug prices continue to present challenges for pharmaceutical market access strategies and societal cost of care. As pharmaceutical companies and medical governmental advisory organizations enter tougher negotiations, hospital trusts and other dispensary firms face barriers to receiving the best medical treatment, and as a result patient access is limited. The 2016 HealthNetwork Communications' Pharma Pricing & Market Access Europe meeting brought together pharmaceutical, medical governmental advisory and stakeholders and market access/pricing consultants, to encourage discussions and negotiations into how to improve the drug pricing system and consequential market access strategies while achieving the respective reimbursement and affordability objectives.

  18. Assessment of micro-scale anaerobic digestion for management of urban organic waste: A case study in London, UK.

    PubMed

    Walker, M; Theaker, H; Yaman, R; Poggio, D; Nimmo, W; Bywater, A; Blanch, G; Pourkashanian, M

    2017-03-01

    This paper describes the analysis of an AD plant that is novel in that it is located in an urban environment, built on a micro-scale, fed on food and catering waste, and operates as a purposeful system. The plant was built in 2013 and continues to operate to date, processing urban food waste and generating biogas for use in a community café. The plant was monitored for a period of 319days during 2014, during which the operational parameters, biological stability and energy requirements of the plant were assessed. The plant processed 4574kg of food waste during this time, producing 1008m(3) of biogas at average 60.6% methane. The results showed that the plant was capable of stable operation despite large fluctuations in the rate and type of feed. Another innovative aspect of the plant was that it was equipped with a pre-digester tank and automated feeding, which reduced the effect of feedstock variations on the digestion process. Towards the end of the testing period, a rise in the concentration of volatile fatty acids and ammonia was detected in the digestate, indicating biological instability, and this was successfully remedied by adding trace elements. The energy balance and coefficient of performance (COP) of the system were calculated, which concluded that the system used 49% less heat energy by being housed in a greenhouse, achieved a net positive energy balance and potential COP of 3.16 and 5.55 based on electrical and heat energy, respectively. Greenhouse gas emissions analysis concluded that the most important contribution of the plant to the mitigation of greenhouse gases was the avoidance of on-site fossil fuel use, followed by the diversion of food waste from landfill and that the plant could result in carbon reduction of 2.95kg CO2eq kWh(-1) electricity production or 0.741kg CO2eq kg(-1) waste treated.

  19. Aircraft trace gas measurements during the London 2012 Olympics: Air quality and emission fluxes derived from sampling upwind and downwind of a megacity

    NASA Astrophysics Data System (ADS)

    Allen, G.; O'Shea, S.; Muller, J.; Jones, B.; O'Sullivan, D.; Lee, J. D.; Bauguitte, S.; Gallagher, M. W.; Percival, C.; Barratt, B.; McQuaid, J. B.; Illingworth, S.

    2013-12-01

    This study presents airborne in situ and remote sensing measurements recorded during July and August 2012, across the period of the London 2012 Summer Olympics and simultaneous with the Clear air for London (ClearfLo) ground-based measurement and modelling campaign. Through long-term (2-year) and intensive observation periods (Winter 2011 and Summer 2012), the ClearfLo programme aims to better understand emissions, as well as the chemical, dynamical and micro-meteorological processes which modulate air quality in the London urban environment - an important risk factor for both acute and chronic health effects. The work presented here focuses on two contrasting case studies within the summer ClearfLo period: 30 July 2012 and 9 August 2012, representing relatively clean background and polluted background cases, respectively, and characterised by well-mixed Atlantic westerly maritime inflow in the former and stagnant air (high pressure) in the latter. Measurements of CO, CO2, CH4, N2O, O3, HCN, and other gases measured on board the UK Facility for Airborne Atmospheric Measurement (FAAM) BAe-146 aircraft will be presented and interpreted, with emphasis on observed concentration gradients and tracer-tracer correlations as well as airmass vertical structure and airmass history upwind and downwind of central London in each case. By applying a simple advective model and making use of vertically resolved thermodynamic and composition data, we are able to derive emission strengths for these gases that are representative of the total enclosed surface area. Example emissions for these two cases range between 6x105 kg(C)/hr and 9x105 kg(C)/hr for CO2, and ~0.6x105 kg(C)/hr for CH4. This airborne sampling methodology highlights the unique utility of aircraft measurements to routinely and climatologically characterise emissions from area sources such as cities, and points to future missions to target localised hotspots and distributed point sources.

  20. Atmospheric ethanol in London and the potential impacts of future fuel formulations.

    PubMed

    Dunmore, Rachel E; Whalley, Lisa K; Sherwen, Tomás; Evans, Mathew J; Heard, Dwayne E; Hopkins, James R; Lee, James D; Lewis, Alastair C; Lidster, Richard T; Rickard, Andrew R; Hamilton, Jacqueline F

    2016-07-18

    There is growing global consumption of non-fossil fuels such as ethanol made from renewable biomass. Previous studies have shown that one of the main air quality disadvantages of using ethanol blended fuels is a significant increase in the production of acetaldehyde, an unregulated and toxic pollutant. Most studies on the impacts of ethanol blended gasoline have been carried out in the US and Brazil, with much less focus on the UK and Europe. We report time resolved measurements of ethanol in London during the winter and summer of 2012. In both seasons the mean mixing ratio of ethanol was around 5 ppb, with maximum values over 30 ppb, making ethanol currently the most abundant VOC in London air. We identify a road transport related source, with 'rush-hour' peaks observed. Ethanol is strongly correlated with other road transport-related emissions, such as small aromatics and light alkanes, and has no relationship to summer biogenic emissions. To determine the impact of road transport-related ethanol emission on secondary species (i.e. acetaldehyde and ozone), we use both a chemically detailed box model (incorporating the Master Chemical Mechanism, MCM) and a global and nested regional scale chemical transport model (GEOS-Chem), on various processing time scales. Using the MCM model, only 16% of the modelled acetaldehyde was formed from ethanol oxidation. However, the model significantly underpredicts the total levels of acetaldehyde, indicating a missing primary emission source, that appears to be traffic-related. Further support for a primary emission source comes from the regional scale model simulations, where the observed concentrations of ethanol and acetaldehyde can only be reconciled with the inclusion of large primary emissions. Although only constrained by one set of observations, the regional modelling suggests a European ethanol source similar in magnitude to that of ethane (∼60 Gg per year) and greater than that of acetaldehyde (∼10 Gg per year). The

  1. Urban organic aerosols measured by single particle mass spectrometry in the megacity of London

    NASA Astrophysics Data System (ADS)

    Dall'Osto, M.; Harrison, R. M.

    2012-05-01

    During the month of October 2006, as part of the REPARTEE-I experiment (Regent's Park and Tower Environmental Experiment) an Aerosol Time-Of-Flight Mass Spectrometer (ATOFMS) was deployed at an urban background location in the city of London, UK. Fifteen particle types were classified, some of which were already discussed (Dall'Osto et al., 2009a,b; Harrison et al., 2012). In this manuscript the origins and properties of four unreported particle types postulated to be due to locally generated aerosols, independent of the air mass type advected into London, are examined. One particle type, originating from lubricating oil (referred to as Ca-EC), was associated with morning rush hour traffic emissions. A second particle type, composed of both inorganic and organic species (called Na-EC-OC), was found enhanced in particle number concentration during evening time periods, and is likely to originate from a source operating at this time of day, or more probably from condensation of semi-volatile species. A third class, internally mixed with organic carbon and sulphate (called OC), was found to spike both in the morning and evenings although it could not unambiguously associated with a specific source or atmospheric process. The fourth class (Secondary Organic Aerosols - Polycyclic Aromatic Hydrocarbon; SOA-PAH) exhibited maximum frequency during the warmest part of the day, and a number of factors point towards secondary aerosol production from traffic-related volatile aromatic compounds. Single particle mass spectra of this particle type showed an oxidized polycyclic aromatic compound signature. A comparison of ATOFMS particle class data is then made with factors obtained by Positive Matrix Factorization and PAH signatures obtained from Aerosol Mass Spectrometer (AMS) data (Allan et al., 2010). Both the Ca-EC and OC particle types correlate with primary Hydrocarbon-like Organic Aerosol (HOA, R2 = 0.65 and 0.50 respectively), and Na-EC-OC correlates weakly with the AMS

  2. Urban organic aerosols measured by single particle mass spectrometry in the megacity of London

    NASA Astrophysics Data System (ADS)

    Dall'Osto, M.; Harrison, R. M.

    2011-02-01

    During the month of October 2006, as part of the REPARTEE-I experiment (Regent's Park and Tower Environmental Experiment) an Aerosol Time-Of-Flight Mass Spectrometer (ATOFMS) was deployed at an urban background location in the city of London, UK. Fifteen particle types were classified, some of which were accompanied by Aerosol Mass Spectrometer (AMS) quantitative aerosol mass loading measurements (Dall'Osto et al., 2009a, b). In this manuscript the origins and properties of four particle types associated with locally generated aerosols, independent of the air mass type advected into London, are examined. One particle type, originating from lubricating oil (referred to as Ca-EC), was associated with morning rush hour traffic emissions. A second particle type, composed of both inorganic and organic species (called Na-EC-OC), was found enhanced in particle number concentration during evening time periods, and is likely to originate from a source operating at this time of day, or more probably from condensation of semi-volatile species, and contains both primary and secondary components. A third class, internally mixed with organic carbon and sulphate (called OC), was found to spike both in the morning and evenings. The fourth class (SOA-PAH) exhibited maximum frequency during the warmest part of the day, and a number of factors point towards secondary production from traffic-related volatile aromatic compounds. Single particle mass spectra of this particle type showed an oxidized polycyclic aromatic compound signature. Finally, a comparison of ATOFMS particle class data is made with factors obtained by Positive Matrix Factorization from AMS data.. Both the Ca-EC and OC particle types correlate with the AMS HOA primary organic fraction (R2 = 0.65 and 0.50 respectively), and Na-EC-OC, but not SOA-PAH, which correlates weakly with the AMS OOA secondary organic aerosol factor (R2 = 0.35). A detailed analysis was conducted to identify ATOFMS particle type(s) representative

  3. Heart failure - medicines

    MedlinePlus

    CHF - medicines; Congestive heart failure - medicines; Cardiomyopathy - medicines; HF - medicines ... You will need to take most of your heart failure medicines every day. Some medicines are taken ...

  4. Anthroposophical medicine: a nursing perspective. Interview by Joanna Trevelyan.

    PubMed

    Bay, F

    1997-12-01

    Despite its popularity on mainland Europe, particularly in Germany and Switzerland, anthroposophical medicine remains relatively unknown in the UK. Joanna Trevelyan takes a closer look at this truly holistic form of medicine, and asks Frances Bay, one of the founders of the Anthroposophical Nurses Association in Great Britain, what it can offer nurses.

  5. UK policy: A success story?

    PubMed Central

    Bradshaw, Jonathan

    2007-01-01

    Child poverty is at the heart of the United Kingdom (UK) government’s social policy agenda. Child poverty rose rapidly in the 1980s; the child poverty rate was one of the highest in Europe by 2000. In 1999, the government’s objective was to reduce child poverty by 50% by 2004/2005, which it narrowly failed to meet. In 2005/2006, there was an increase in child poverty. An index of child well-being found that the UK was 21st out of the 25 European Union countries. Overall, the UK came in last in the UNICEF well-being index. The government’s child poverty strategy has been to manage the economy to maximize employment and to improve in-work incomes. Both have been successful in reducing child poverty. Out-of-work incomes have also been improved, but not enough to lift many children out of poverty. Public expenditure on services, especially health, education and childcare, has also increased; although there are questions about how much of this extra spending has focused on children and child poverty. The comprehensive spending review, reporting later in 2007, is likely to be tight, and it is now unlikely that the government will succeed in its aim of reducing child poverty by 50% by 2010 unless there are radical changes in policy. Constraints on the government’s ability to do this include the structural inequalities in British society and public attitudes toward people in poverty. PMID:19030446

  6. Nutritional knowledge of UK coaches.

    PubMed

    Cockburn, Emma; Fortune, Alistair; Briggs, Marc; Rumbold, Penny

    2014-04-10

    Athletes obtain nutritional information from their coaches, yet their competency in this area is lacking. Currently, no research exists in the UK which has a different coach education system to many other countries. Therefore, the aim of this study was to evaluate the sports nutrition knowledge of UK coaching certificate (UKCC) level 2 and 3, hockey and netball qualified coaches. All coaches (n = 163) completed a sports nutrition questionnaire to identify: (a) if they provided nutritional advice; (b) their level of sport nutrition knowledge; and (c) factors that may have contributed to their level of knowledge. Over half the coaches provided advice to their athletes (n = 93, 57.1%), even though they were not competent to do so. Coaches responded correctly to 60.3 ± 10.5% of all knowledge questions with no differences between those providing advice and those who did not (p > 0.05). Those coaches who had undertaken formal nutrition training achieved higher scores than those who had not (p < 0.05). In conclusion, UK sports coaches would benefit from continued professional development in sports nutrition to enhance their coaching practice.

  7. Equine uveitis: a UK perspective.

    PubMed

    Lowe, R C

    2010-03-01

    Uveitis in the equine population of the UK does not appear to be as prevalent or disastrous as seen across regions of Europe and the USA. Some cases perceived to be recurrent uveitis may be poorly resolved single episodes of uveitis and care should be taken not to make the diagnosis of recurrence without ensuring effective control of the initial episode. Leptospira spp. appear to play only a minor role ERU in the UK which is probably the main reason for the prevalence of the disease being much lower compared to the USA and mainland Europe. Actual data are relatively few on the ground as far as disease surveillance in concerned. This has 2 implications. Firstly unless we are able to effectively monitor the levels of uveitic disease, it will be difficult to pick up early changes in the trend which may allow quicker intervention. Secondly, it is difficult to secure funding for further research if the prevalence of the problem is poorly defined. This may leave the UK equine population at risk should the disease profile suddenly alter for the worse.

  8. Regional inequality in radiology research output in the UK: a 5-year bibliometric study.

    PubMed

    Yoong, P; Johnson, C A; Rehman, J M; Toms, A P

    2012-11-01

    The objective of this study was to describe the patterns of peer-reviewed general radiology publication rates with reference to deaneries in the UK. This was a retrospective bibliometric analysis of publications in the six highest cited general radiology journals. Publications were identified using a manual search in PubMed between 2005 and 2009. Publications originating from UK radiology departments were identified and subcategorised into primary institution of origin, deanery and publication type. The total number of radiology trainees in each deanery was obtained from the General Medical Council. 913 publications were included in the study. Original papers constituted 48.7% (n=445), review articles 30.3% (n=277) and case reports 17.4% (n=159). The median number of publications in each deanery was 27 [interquartile range (IQR) 11-60], and the median number of publications per trainee was 0.49 (IQR 0.31-0.88). The largest proportion of publications came from the London deanery (n=354, 38.8%), followed by Eastern 86 (9.4%), Oxford and Yorkshire 70 (7.7% each). Relative to the number of trainees within each deanery, Oxford had the highest number of publications per trainee (1.78), followed by East Midlands (1.5), London (1.25) and Eastern (0.99). There was a significantly higher publication rate for those deaneries with academic radiologists (p<0.0001). There is a marked difference in the volume of published work in the general radiology literature among UK deaneries, even accounting for differences in the number of trainees. This probably means that opportunities for training in research are similarly non-uniform.

  9. Air pollution dispersion models for human exposure predictions in London.

    PubMed

    Beevers, Sean D; Kitwiroon, Nutthida; Williams, Martin L; Kelly, Frank J; Ross Anderson, H; Carslaw, David C

    2013-01-01

    The London household survey has shown that people travel and are exposed to air pollutants differently. This argues for human exposure to be based upon space-time-activity data and spatio-temporal air quality predictions. For the latter, we have demonstrated the role that dispersion models can play by using two complimentary models, KCLurban, which gives source apportionment information, and Community Multi-scale Air Quality Model (CMAQ)-urban, which predicts hourly air quality. The KCLurban model is in close agreement with observations of NO(X), NO(2) and particulate matter (PM)(10/2.5), having a small normalised mean bias (-6% to 4%) and a large Index of Agreement (0.71-0.88). The temporal trends of NO(X) from the CMAQ-urban model are also in reasonable agreement with observations. Spatially, NO(2) predictions show that within 10's of metres of major roads, concentrations can range from approximately 10-20 p.p.b. up to 70 p.p.b. and that for PM(10/2.5) central London roadside concentrations are approximately double the suburban background concentrations. Exposure to different PM sources is important and we predict that brake wear-related PM(10) concentrations are approximately eight times greater near major roads than at suburban background locations. Temporally, we have shown that average NO(X) concentrations close to roads can range by a factor of approximately six between the early morning minimum and morning rush hour maximum periods. These results present strong arguments for the hybrid exposure model under development at King's and, in future, for in-building models and a model for the London Underground.

  10. The psychological and psychiatric effects of terrorism: lessons from London.

    PubMed

    Rubin, G James; Wessely, Simon

    2013-09-01

    The 7 July 2005 bombings in London caused heightened levels of distress among some in the general community. This distress was most notable in Muslims and members of ethnic minority groups. These effects were transient for most. An estimated 30% of those who were more affected by the attacks, including victims and witnesses, developed psychiatric disorders as a result. An outreach program was set up to screen those who were exposed to potentially traumatic events and to offer them evidence-based treatment. This article discusses what lessons might be learned from studies of the general community and the screen-and-treat approach.

  11. Two daily smoke maxima in eighteenth century London air

    NASA Astrophysics Data System (ADS)

    Harrison, R. Giles

    Varied electrostatics experiments followed Benjamin Franklin's pioneering atmospheric investigations. In Knightsbridge, Central London, John Read (1726-1814) installed a sensing rod in the upper part of his house and, using a pith ball electrometer and Franklin chimes, monitored atmospheric electricity from 1789 to 1791. Atmospheric electricity is sensitive to weather and smoke pollution. In calm weather conditions, Read observed two daily electrification maxima in moderate weather, around 9 am and 7 pm. This is likely to represent a double diurnal cycle in urban smoke. Before the motor car and steam railways, one source of the double maximum smoke pattern was the daily routine of fire lighting for domestic heating.

  12. Lessons for climate policy from The Great Stink of London

    NASA Astrophysics Data System (ADS)

    Skuce, A.

    2012-12-01

    A rapidly growing population and the introduction of the flush toilet in nineteenth-century London caused a crisis with sewage pollution in the River Thames (Halliday, 1999). There were decades of delays in implementing solutions owing to: inadequate governance institutions; political inertia; difficulties with financing; opposition from vested interests; scientific uncertainties; and technological challenges. Effective counter-measures were started only once the problem arose, quite literally, under the noses of parliamentarians. There are parallels, some of them pointed out earlier by Alley et al (2010), between the sewage crisis in Victorian London and the current problem with climate change. Both involve the unsustainable use of a common resource (a river, the atmosphere) for the unconstrained disposal of human waste products. Alley (2011) estimated that the costs of providing clean water and sanitation are comparable to the expected costs of reducing greenhouse gas emissions. Despite the similarities, the climate change issue is actually much more difficult because of: a) the unequal and uncertain global distribution of cause and effect; b) its long, intergenerational time lines; c) the insufficiency of adequate institutions, conventions or the tools— political, moral or economic—for tackling the climate crisis. This analysis is consistent with the model proposed by Gardiner (2011) in his book A Perfect Moral Storm. The three "storms" he identifies, the global, intergenerational and theoretical storms, combine in a powerful synergy to create a challenge of unprecedented intractability, providing opportunities for what Gardiner calls moral corruption: the obscuring of the buck-passing and procrastination that characterizes climate policy today. In Victorian London, the crucial steps to solve the sewage crises were not taken until the stench from the River Thames during the hot summer of 1858 rendered the House of Commons uninhabitable. A greater stink of a

  13. Personal exposures to airborne metals in London taxi drivers and office workers in 1995 and 1996.

    PubMed

    Pfeifer, G D; Harrison, R M; Lynam, D R

    1999-09-01

    In 1995, a petroleum marketer introduced a diesel fuel additive in the UK containing Mn as MMT (methylcyclopentadienyl manganese tricarbonyl). A small study of personal exposures to airborne Mn in London was conducted before and after introduction of the additive to identify any major impact of the additive on exposures. In 1995, personal exposures to Mn were measured in two groups, taxi drivers and office workers (10 subjects per group) for two consecutive 7-day periods. A similar study was carried out in 1996 to determine if exposures had changed. Samples were also analyzed for Ca, Al, Mg and Pb. In 1996, exposures to aerosol mass as total suspended particulates (TSP) and PM2.5 were measured in addition to the metals. Manganese exposures in this cohort did not increase as a result of introduction of the additive. However, a significant source of Mn exposure was discovered during the conduct of these tests. The mean exposure to Mn was higher among the office workers in both years than that of the taxi drivers. This was due to the fact that approximately half of the office workers commuted via the underground railway system where airborne dust and metal concentrations are significantly elevated over those in the general environment. Similar results have been noted in other cities having underground rail systems. Exposure to Mn, Pb, Ca, and Mg were not significantly different between the 2 years. Taxi drivers had higher exposures than office workers to Mg and Pb in both years. Commuting via the underground also had a significant impact on exposures to TSP, PM2.5, Al, and Ca, but had little effect on exposures to Mg. The aerosol in the underground was particularly enriched in Mn, approximately 10-fold, when compared to the aerosol in the general environment. There are several possible sources for this Mn, including mechanical wear of the steel wheels on the steel rais, vaporization of metal from sparking of the third rail, or brake wear.

  14. Integrating research & teaching: the Queen Mary, University of London module in Geodiversity & Geoconservation

    NASA Astrophysics Data System (ADS)

    Gray, M.

    2012-04-01

    The School of Geography at Queen Mary, University of London has been running a Level 6 (undergraduate) module in "Geodiversity & Geoconservation" since 2004. The course is based around the book Geodiversity: valuing and conserving abiotic nature (John Wiley, 2004) but lectures are used to update each topic based on the latest research. The course is divided into 5 parts: 1. Defining and describing geodiversity - which discusses the concept of geodiversity, its definition and the nature of the geodiversity of Planet Earth; 2. Values of, and threats to, geodiversity - a lecture on valuing geodiversity is now based around important research on the role of geodiversity in "ecosystem services" assessments. A second lecture covers the major threats to geodiversity; 3. The protected area approach - lectures here cover geological World Heritage Sites, Global Geoparks, GSSPs, and national geoconservation systems in the UK, USA and other parts of the world; 4. Protecting geodiversity in the wider landscape - the contribution of geology and geomorphology to landscape character are described, together with the role of land-use planning and policy-making in protecting geodiversity. 5. Putting it all together - lectures here emphasize that geodiversity is an important basis for geoconservation, that different geoconservation methods are appropriate to different elements of geodiversity, and that integrated geo/bio conservation is essential. A field trip to three Chalk/Quaternary Sites of Special Scientific Interest in East Sussex is included which discusses some of the planning issues that have arisen at these sites, a theme that is expanded in the lectures.

  15. Concentrations of selected volatile organic compounds at kerbside and background sites in central London

    NASA Astrophysics Data System (ADS)

    Valach, A. C.; Langford, B.; Nemitz, E.; MacKenzie, A. R.; Hewitt, C. N.

    2014-10-01

    Ground-level concentrations of nine volatile organic compounds (VOCs) were measured using a proton transfer reaction-mass spectrometer (PTR-MS) in central London at an urban background (North Kensington, NK, during 16th-25th Jan 2012) and a kerbside site (Marylebone Rd, MRd, during 25th Jan-7th Feb 2012) as part of the winter intensive observation period of the ClearfLo project. Site comparisons indicated that VOC concentrations at the urban background site were significantly lower than at the kerbside site (ratio MRd/NK of 2.3). At the kerbside site PTR-MS measurements of aromatics (benzene, toluene, C2- and C3-benzenes) were compared with the gas chromatography - flame ionization detector data from the UK Government's Automatic Hydrocarbon Network. Very good qualitative agreement was observed between the two methods (r = 0.90-0.91, p < 0.001, N = 260), although there was a significant offset between the instruments. This was partly due to issues with humidity dependent background measurements, but possibly also from isobaric interference of other compounds and their fragments, giving a positive bias to the PTR-MS data. Most compounds showed strong indications of traffic-related sources with double rush hour peaks in diurnal profiles and high correlations with known traffic-related compounds (r = 0.68-0.97 at NK, 0.48-0.87 at MRd, p < 0.001, NNK = 2202-2227, NMRd = 2705-2720) and CO (r = 0.80-0.96 at NK, 0.65-0.84 at MRd, p < 0.001, NNK = 223, NMRd = 256-274). Polar plots agreed with statistical analysis of wind direction dependency and identification of potential emission sources was attempted.

  16. Food, home and health: the meanings of food amongst Bengali Women in London

    PubMed Central

    2014-01-01

    Background This paper explores the nature of food and plants and their meanings in a British Bengali urban context. It focuses on the nature of plants and food in terms of their role in home making, transnational connections, generational change and concepts of health. Methods An ethnographic approach to the research was taken, specific methods included participant observation, focus group discussions and semi-structured interviews. Thirty women of Bengali origin were mostly composed of “mother” and “daughter” pairs. The mothers were over 45 years old and had migrated from Bangladesh as adults and their grown-up daughters grew up in the UK. Results Food and plants play an important role in the construction of home “here” (London) while continuing to connect people to home “there” (Sylhet). This role, however, changes and is re-defined across generations. Looking at perceptions of “healthy” and “unhealthy” food, particularly in the context of Bengali food, multiple views of what constitutes “healthy” food exist. However, there appeared to be little two-way dialogue about this concept between the research participants and health professionals. This seems to be based on “cultural” and power differences that need to be addressed for a meaningful dialogue to occur. Conclusion In summary, this paper argues that while food is critical to the familial spaces of home (both locally and globally), it is defined by a complex interplay of actors and wider meanings as illustrated by concepts of health and what constitutes Bengali food. Therefore, we call for greater dialogue between health professionals and those they interact with, to allow for an enhanced appreciation of the dynamic nature of food and plants and the diverse perceptions of the role that they play in promoting health. PMID:24886061

  17. Preparing for Disaster: Response Matrices in the USA and UK

    PubMed Central

    Kahn, Laura H.

    2008-01-01

    Disasters, whether man-made or naturally occurring, require complex responses across multiple government agencies and private sector elements, including the media. These factors mandate that, for effective disaster management and because of the unpredictability of such events, response structures must be in place in advance, ready to be activated on short notice, with lines of responsibility clearly delineated and mechanisms for coordination of efforts already established. Disaster response experiences in the USA and the UK were reviewed at a conference convened by the New York Academy of Medicine and the Royal Society of Medicine in June 2007. Lessons to be drawn from these comparisons were sought. The importance of careful advance planning, clear delineation of spheres of responsibility and response roles, effective mechanisms for communication at all levels, and provision for adequate communication with the public were all identified as key elements of effective response mechanisms. PMID:18756376

  18. Solitary Reapers: Reading Cultural Interjections in a London School

    ERIC Educational Resources Information Center

    Shah, Mehrunissa

    2014-01-01

    This essay explores the problematic nature of an enforced monolingual culture promoted by the current Conservative-led UK government. It comments upon the paradoxical nature of the 2014 curriculum that promotes heritage texts and "proper" English, when such poets embraced a Bakhtinian tolerance of languages. It focuses primarily upon the…

  19. Creating the Strategic Learning Environment at City University London

    ERIC Educational Resources Information Center

    Quinsee, Susannah; Bullimore, Anise

    2011-01-01

    Purpose: This paper aims to describe the creation of a new approach to the implementation of educational technologies at a UK Higher Education Institution. Driven by changes in technology, an evaluation of the virtual learning environment (VLE) provided the opportunity to reassess the application of technology to the curriculum. However, such an…

  20. Daytime CO2 Urban-Regional Scale Surface Fluxes from Airborne Measurements, Eddy-Covariance Observations and Emissions Inventories in Greater London

    NASA Astrophysics Data System (ADS)

    Font, A. M.; Grimmond, S. B.; Morgui, J. A.; Kotthaus, S.; Priestman, M.; Barratt, B.

    2014-12-01

    As the global population becomes increasingly urbanized, spatially concentrated centres of anthropogenic CO2 and other greenhouse gases (GHG) arise. While mitigation measures exist at national and international scales, their implementation will be more effective if linked to the urban-scale of the sources. Routine top-down approaches that quantify emissions of GHG from cities and megacities are needed to understand the dynamics of the urban carbon cycle to eventually define relevant policy decisions. London is the biggest urban conurbation in Western Europe with more than 8 million inhabitants. It emitted roughly 45000 ktn CO2 in 20101. To understand the carbon dynamics and quantify anthropogenic emissions from London, airborne surveys of atmospheric CO2, O3, particles and meteorological variables were carried out over the city, onboard the NERC-ARSF Dornier-228 UK research aircraft. We applied an Integrative Mass Boundary Layer method (IMBL) using airborne CO2 observations obtained in horizontal transects crossing London at 360 m at different times of the day and by sampling upwind-downwind profiles. IMBL CO2 fluxes were compared to an emissions inventory and neighbourhood-scale eddy-covariance fluxes in central London. Daytime fluxes in October 2011 from the IMBL calculations ranged from 46 to 104 μmolCO2 m-2 s-1 and covered 30-70% of the urban region. The IMBL CO2 fluxes were the same order of magnitude as observed eddy-covariance fluxes and were statistically comparable to the emission inventory for the same footprint area. A sensitivity analysis suggested that horizontal variability of the CO2 field in the urban mixing layer is the most critical factor affecting IMBL fluxes. The determination of the boundary height and vertical wind speed had more impact on fluxes calculated from upwind-downwind profiles. Furthermore, low-altitude airborne measurements of CO2 provide the advantage of direct observation of the CO2 urban dome of a megacity and relate the

  1. UK Nova/Supernova Patrol - the first 25 years

    NASA Astrophysics Data System (ADS)

    Hurst, G. M.

    2003-06-01

    The text of the Presidential Address delivered at 23 Savile Row, London W1 on 2002 October 30. The challenge of this Presidential Address is to compress the events of the first 25 years of the UK Nova/Supernova Patrol into a talk lasting for about an hour. When the patrol began as a formal search programme all that time ago, I had no idea just how much would be achieved and I feel quite humble in presenting the results as the coordinator when the real work has been carried out by all those dedicated observers over the years, whether looking for novae with binoculars or those now employing the latest technology to detect extragalactic supernovae. I will describe how and why the patrol started in 1976, including earlier events that persuaded key individuals that the time had come for a team approach to searching for novae. The aims of the patrol will be discussed and how these have changed over the years, which has necessitated some rethinking of the techniques employed. Naturally the patrol discoveries will be discussed in detail, but also the vital follow-up work on novae and supernovae, such as light curve analysis, which can produce valuable scientific information for the professional community. Indeed the patrol's work has generated excellent professional-amateur liaison as each side has helped the other to increase our understanding of these somewhat elusive objects, which suddenly burst into view in the night sky.

  2. How to read Simon Forman's casebooks: medicine, astrology, and gender in Elizabethan London.

    PubMed

    Kassel, L

    1999-04-01

    Simon Forman's astrological casebooks record thousands of medical consultations. Amidst the wealth of information in these documents, however, it is unclear to what extent Forman relied on the stars for diagnoses and therapies, or how the casebooks reflect the dymanic between Forman and his clients. This article attempts to answer these questions by reading the casebooks alongside Forman's guide to astrological physic. This approach reveals that astrology was paramount in Forman's evaluations and treatments of his patients. According to Forman, in order for him to effect a cure, he had to be trusted. It was particularly difficult to treat women because their health depended on the state of their wombs, and on their sexual activity, subjects about which women were notoriously duplicitous. The task of the astrologer was first to assess whether or not a woman was sexually active, and only then could he make a judgement about her disease. At the same time, in demonstrating an ability to discern whether or not she was being honest about her sexual activities, Forman won her confidence. By accounting for the role of astrology and the dynamics between the patient and the physician, this article provides the framework within which to read one of the most comprehensive records of medical practices in early modern England.

  3. Observation of the London moment and trapped flux in precision gyroscopes

    NASA Technical Reports Server (NTRS)

    Xiao, Y. M.; Felson, W.; Wu, C. H.; Keiser, G. M.; Turneaure, J. P.

    1993-01-01

    The London-moment readout has been observed in flight quality gyroscopes and it has been demonstrated that it is possible to reduce magnetic field trapped in these gyroscopes to levels as low as 1.5 x 10 exp -11 T. A preliminary analysis shows that the horizontal component of the London-moment signal is 60 percent of the total expected London-moment signal and is proportional to the gyro spin speed. Experiments were carried out in a unique ground test facility which was designed to provide the conditions necessary to observe the London moment of the spinning gyroscope.

  4. Public health assessment for US Naval Submarine Base, New London, Groton, New London County, Connecticut, Region 1. CERCLIS No. CTD980906515. Final report

    SciTech Connect

    Not Available

    1993-05-26

    The New London Submarine Base was divided by the town boundaries of Groton to the south and Ledyard to the north in New London County, Connecticut. In 1983, the Navy identified 16 potential source areas of environmental contamination during their investigations. The submarine base was listed on the US Environmental Protection Agency's National Priorities List in August 1990 because of the potential for on-base groundwater contamination to migrate to off-base residential wells that are close to the New London Submarine Base.

  5. Space-Time Analysis of Crime Patterns in Central London

    NASA Astrophysics Data System (ADS)

    Cheng, T.; Williams, D.

    2012-07-01

    Crime continues to cast a shadow over citizen well-being in big cities today, while also imposing huge economic and social costs. Timely understanding of how criminality emerges and how crime patterns evolve is crucial to anticipating crime, dealing with it when it occurs and developing public confidence in the police service. Every day, about 10,000 crime incidents are reported by citizens, recorded and geo-referenced in the London Metropolitan Police Service Computer Aided Dispatch (CAD) database. The unique nature of this dataset allows the patterns to be explored at particularly fine temporal granularity and at multiple spatial resolutions. This study provides a framework for the exploratory spatio-temporal analysis of crime patterns that combines visual inquiry tools (interactive animations, space-time cubes and map matrices) with cluster analysis (spatial-temporal scan statistics and the self-organizing map). This framework is tested on the CAD dataset for the London Borough of Camden in March 2010. Patterns of crime through space and time are discovered and the clustering methods were evaluated on their ability to facilitate the discovery and interpretation of these patterns.

  6. On the exchange-hole model of London dispersion forces

    NASA Astrophysics Data System (ADS)

    Ángyán, János G.

    2007-07-01

    First-principles derivation is given for the heuristic exchange-hole model of London dispersion forces by Becke and Johnson [J. Chem. Phys. 122, 154104 (2005)]. A one-term approximation is used for the dynamic charge density response function, and it is shown that a central nonempirical ingredient of the approximate nonexpanded dispersion energy is the charge density autocorrelation function, a two-particle property, related to the exchange-correlation hole. In the framework of a dipolar approximation of the Coulomb interaction around the molecular origin, one obtains the so-called Salem-Tang-Karplus approximation to the C6 dispersion coefficient. Alternatively, by expanding the Coulomb interaction around the center of charge (centroid) of the exchange-correlation hole associated with each point in the molecular volume, a multicenter expansion is obtained around the centroids of electron localization domains, always in terms of the exchange-correlation hole. In order to get a formula analogous to that of Becke and Johnson, which involves the exchange-hole only, further assumptions are needed, related to the difficulties of obtaining the expectation value of a two-electron operator from a single determinant. Thus a connection could be established between the conventional fluctuating charge density model of London dispersion forces and the notion of the "exchange-hole dipole moment" shedding some light on the true nature of the approximations implicit in the Becke-Johnson model.

  7. Combined heat and power for the City of London

    SciTech Connect

    Mullins, P.

    1994-06-01

    The first phase of an innovative combined heat and power (CHP) system for the City of London is now almost complete and should be operating at full capacity by the end of 1994. Test runs are taking place. The system is powered by two large 18-cylinder Waertsilae Vasa 46GD multifuel engines developing a total of just under 32 MW of power. The engines drive ABB Stromberg HSG 160O water-cooled generators with electrical efficiencies exceeding 97%. The station will use natural gas and heavy fuel oil to generate electricity for the grid, hot water for district heating and chilled water for air conditioning. In the first phase of the project, underground pipework and cabling will connect the power station to various buildings in the City including the Barbican Center, Guildhall and the Museum of London/Bastion House. State-of-the-art emission control equipment has been installed to reduce NO[sub x] and SO[sub 2] by over 90%. 5 figs.

  8. Genomics education for medical professionals - the current UK landscape.

    PubMed

    Slade, Ingrid; Subramanian, Deepak N; Burton, Hilary

    2016-08-01

    Genomics education in the UK is at an early stage of development, and its pace of evolution has lagged behind that of the genomics research upon which it is based. As a result, knowledge of genomics and its applications remains limited among non-specialist clinicians. In this review article, we describe the complex landscape for genomics education within the UK, and highlight the large number and variety of organisations that can influence, direct and provide genomics training to medical professionals. Postgraduate genomics education is being shaped by the work of the Health Education England (HEE) Genomics Education Programme, working in conjunction with the Joint Committee on Genomics in Medicine. The success of their work will be greatly enhanced by the full cooperation and engagement of the many groups, societies and organisations involved with medical education and training (such as the royal colleges). Without this cooperation, there is a risk of poor coordination and unnecessary duplication of work. Leadership from an organisation such as the HEE Genomics Education Programme will have a key role in guiding the formulation and delivery of genomics education policy by various stakeholders among the different disciplines in medicine.

  9. Uveal Melanoma UK National Guidelines.

    PubMed

    Nathan, P; Cohen, V; Coupland, S; Curtis, K; Damato, B; Evans, J; Fenwick, S; Kirkpatrick, L; Li, O; Marshall, E; McGuirk, K; Ottensmeier, C; Pearce, N; Salvi, S; Stedman, B; Szlosarek, P; Turnbull, N

    2015-11-01

    The United Kingdom (UK) uveal melanoma guideline development group used an evidence based systematic approach (Scottish Intercollegiate Guidelines Network (SIGN)) to make recommendations in key areas of uncertainty in the field including: the use and effectiveness of new technologies for prognostication, the appropriate pathway for the surveillance of patients following treatment for primary uveal melanoma, the use and effectiveness of new technologies in the treatment of hepatic recurrence and the use of systemic treatments. The guidelines were sent for international peer review and have been accredited by NICE. A summary of key recommendations is presented. The full documents are available on the Melanoma Focus website.

  10. UK mining invests, suppliers profit

    SciTech Connect

    2009-04-15

    In the midst of a major economic crisis in the United Kingdom, equipment suppliers have been reporting a number of considerable purchases by British coal mining companies. In December 2008, Liebherr-Great Britain delivered the first two of four Rq350 Litronic hydraulic excavators for use at the Broken Cross opencast coal site in Lanarkshire, Scotland. Ten Terex TR100 rigid haulers were delivered to the site in late 2008. Hatfield Colliery at Stainforth, South Yorkshire, has been reopened by PowerFuel. The main equipment for two longwall faces was supplied by Joy Mining Machinery UK Ltd. 2 photos.

  11. Herbal Medicine

    MedlinePlus

    ... for its scent, flavor, or therapeutic properties. Herbal medicines are one type of dietary supplement. They are ... and fresh or dried plants. People use herbal medicines to try to maintain or improve their health. ...

  12. Diabetes Medicines

    MedlinePlus

    Diabetes means your blood glucose, or blood sugar, levels are too high. If you can't control your diabetes with wise food choices and physical activity, you may need diabetes medicines. The kind of medicine you take depends ...

  13. Validation of an instrument to measure patients’ experiences of medicine use: the Living with Medicines Questionnaire

    PubMed Central

    Krska, Janet; Katusiime, Barbra; Corlett, Sarah A

    2017-01-01

    Background Medicine-related burden is an increasingly recognized concept, stemming from the rising tide of polypharmacy, which may impact on patient behaviors, including nonadherence. No instruments currently exist which specifically measure medicine-related burden. The Living with Medicines Questionnaire (LMQ) was developed for this purpose. Objective This study validated the LMQ in a sample of adults using regular prescription medicines in the UK. Methods Questionnaires were distributed in community pharmacies and public places in southeast England or online through UK health websites and social media. A total of 1,177 were returned: 507 (43.1%) from pharmacy distribution and 670 (56.9%) online. Construct validity was assessed by principal components analysis and item reduction undertaken on the original 60-item pool. Known-groups analysis assessed differences in mean total scores between participants using different numbers of medicines and between those who did or did not require assistance with medicine use. Internal consistency was assessed by Cronbach’s alpha. Free-text comments were analyzed thematically to substantiate underlying dimensions. Results A 42-item, eight-factor structure comprising intercorrelated dimensions (patient–doctor relationships and communication about medicines, patient–pharmacist communication about medicines, interferences with daily life, practical difficulties, effectiveness, acceptance of medicine use, autonomy/control over medicines and concerns about medicine use) was derived, which explained 57.4% of the total variation. Six of the eight subscales had acceptable internal consistency (α>0.7). More positive experiences were observed among patients using eight or fewer medicines compared to nine or more, and those independent with managing/using their medicines versus those requiring assistance. Free-text comments, provided by almost a third of the respondents, supported the domains identified. Conclusion The resultant LMQ

  14. [SPORT MEDICINE].

    PubMed

    Constantini, Naama; Mann, Gideon

    2016-06-01

    Sports Medicine is a relatively new subject in medicine and includes a variety of medical and paramedical fields. Although sports medicine is mistakenly thought to be mainly for sports professionals/athletes, it actually encompasses the entire population, including the active and non-active healthy populations, as well as the sick. Sports medicine also engages amateur sportsmen and strives to promote physical activity and quality of life in the general population. Hence, the field involves all ages from childhood to old age, aiming to preserve and support every person at every age. Sports medicine, which started developing in the 19th century, is today a specialty, primary or secondary, in many countries, while in others it is a fellowship or under the jurisdiction of local or sports authorities. In Israel, the field exists since the 1950's and is advanced. The Sports Medicine Society founded a 3-year course of continued education in sport medicine as part of the Tel-Aviv University Faculty of Medicine. Later on, a fellowship in general Sports Medicine and in Orthopedic Sports Medicine were developed within the Israel Medical Association. A year ago, Israel formally became a member of the global "Exercise is Medicine" foundation, and under this title promotes education for health care providers on exercise prescription. The understanding of the importance of physical activity and fitness as part of a healthy lifestyle is increasing in Israel, as well as the number of amateur athletes, and the profession of sports medicine takes a big part in this process.

  15. The passing of the night watch: night nursing reform in the London teaching hospitals, 1856-90.

    PubMed

    Helmstadter, C

    1994-01-01

    At the beginning of the nineteenth century a separate team of women called the "night watch" was responsible for the night nursing in the London teaching hospitals. Rough, uneducated, and frequently the "scrubbers," or charwomen, who cleaned the halls and stairways in the hospitals in the daytime, the night watchers came to be closely identified with Dickens's Sarah Gamp. As the century progressed, the expanding capabilities of the new academic medicine forced an improvement in the standard of nursing. The difficulty in finding clinically experienced nurses who were willing to work nights at an affordable price, however, made it possible for the night watchers to remain in the new professionally organized hospital long after such unskilled and undisciplined workers had been phased out of other areas of the late Victorian workforce. By the end of the century when hospitals began rotating partially trained probationer, or student, nurses onto nights, the night watchers finally disappeared from the teaching hospitals.

  16. An Introduction to ESERO-UK, the UK Space Education Office

    ERIC Educational Resources Information Center

    Clements, Allan; Mather, Edward

    2012-01-01

    This article introduces the UK branch of the European Space Education Resource Office (ESERO-UK), also known as the UK Space Education Office. It is a teaching project designed to use space to enthuse primary and secondary students to study science, technology, engineering and mathematics (STEM) subjects. The office is funded by the European Space…

  17. Did the London Initiative Zone investment programme affect general practice structure and performance in East London? A time series analysis of cervical screening coverage and asthma prescribing.

    PubMed

    Naish, J; Eldridge, S; Moser, K; Sturdy, P

    2002-11-01

    A programme of incentives was set up in the London Initiative Zones to improve primary care in inner London based on the findings of the Tomlinson Enquiry in 1992. This descriptive study is a 4-y time series analysis of changes in general practice structure in East London as the result of London Initiative Zone investment, and an exploration of the possible effect of investment on practice performance. We used routinely available administrative data for the whole analysis. General practice characteristics and two selected performance indicators: the asthma prophylaxis to bronchodilator ratio and cervical cytology screening rate, for all practices in the East London and the City Health Authority for 4 y, 1993-1996, were used. Both reflect practice efficiency, but relate to different aspects of practice performance. The prescribing indicator is more indicative of the quality of clinical practise, whereas cervical screening coverage relates more to the characteristics of the practice population and to practice organisation. Repeated measures analyses were used to identify trends and to explore the relationship between changes in practice characteristics and performance. Graphical methods were used to compare East London trends with the rest of England. There were significant improvements in practice structure as the consequence of London Initiative Zone investment. There was a positive association with improvements in practice performance, but East London still lagged some way behind national patterns. The findings suggest that while improvements in asthma prescribing follow the national trend, practices have difficulty in achieving and sustaining the 80% target for cervical cytology screening, and that an overall population coverage of 80% may be in doubt.Increased investment in practice staffing may be influential in improving some aspects of performance. However, in common with other inner cities, a greater effort and more innovative strategies may be needed to

  18. The ethics of dental practice in London in the sixteenth century. 1. Henry Chettle's Kind-Harts dreame of 1592. An important lay view.

    PubMed

    Bishop, M

    2012-07-13

    Kind-Harts dreame (Fig. 1) is one of the proto-novels which first appeared in the Elizabethan age of literary wonders. It recounts the dream of the hero - a tooth-drawer (Kind-Hart) - who encounters the shades of five recently deceased characters, each of whom had been a famous star of their day in the London scene. Although short, and with medicine and dentistry occupying only part of the tale, the story contains invaluable detailed information about dental care in late Tudor England as observed by a layman. It is also an amusing read.

  19. Alienating evidence based medicine vs. innovative medical device marketing: a report on the evidence debate at a Wounds conference.

    PubMed

    Madden, Mary

    2012-06-01

    Wound care management is one of the largest segments of the UK medical technology sector with a turnover exceeding £1bn in 2009 (BIS, 2010). Using data derived from participant observation, this article examines the antagonistic relationship expressed by wound care clinicians towards evidence based medicine in the context of the 2010 United Kingdom (UK) Wounds UK conference/trade show, where evidence based medicine is positioned in opposition to clinical knowledge, as an obstacle to innovation and as a remover of solutions rather than a provider of them. The article is written in the context of the trend towards increasing marketization and privatization in the UK National Health Service (NHS).

  20. Engendering City Politics and Educational Thought: Elite Women and the London Labour Party, 1914-1965

    ERIC Educational Resources Information Center

    Martin, Jane

    2008-01-01

    This article uses biographical approaches to recover the contribution of hitherto neglected figures in the history of education and the political history of the Left in London. Place and location are important since it is important to grasp the uniqueness of the London County Council within the framework of English local government and of the…

  1. The Increasing Presence of Spanish-Speaking Latinos in London: An Emergent Community?

    ERIC Educational Resources Information Center

    Block, David

    2008-01-01

    In recent years, the number of Spanish-speaking Latinos in Britain and London has grown considerably. Estimates from different sources put the population in London as high as 300,000. Unfortunately, this growing ethnolinguistic group is an underresearched minority, and information of any kind is hard to come by. In this article, my aim is to…

  2. 77 FR 67566 - Regulated Navigation Area; Thames River Degaussing Range Replacement Operations; New London, CT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-13

    ... Coast Guard is temporarily establishing a regulated navigation area (RNA) on the navigable waters of the Thames River in New London Harbor, New London, CT. The RNA will establish speed and wake restrictions and allow the Coast Guard to prohibit all vessel traffic through the RNA during degaussing range...

  3. 77 FR 54495 - Regulated Navigation Area; Thames River Degaussing Range Replacement Operations; New London, CT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... Coast Guard proposes to establish a regulated navigation area (RNA) on the navigable waters of the Thames River in New London Harbor, New London, CT. The proposed RNA would establish speed and wake restrictions as well as allow the Coast Guard to prohibit all vessel traffic through the RNA during...

  4. Report to the Vincent Astor Foundation; New York/London Middle School Conference.

    ERIC Educational Resources Information Center

    New York Urban Coalition, NY.

    The New York-London Middle Schools Project of 1976 provided an opportunity for a representative group of London educators to study New York City's public school system in terms of school community relations, school based planning and staff development at the junior high/intermediate school level. In this report, British educators provide a brief…

  5. 33 CFR 334.75 - Thames River, Naval Submarine Base New London, restricted area.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....75 Thames River, Naval Submarine Base New London, restricted area. (a) The area: The open waters of... restricted area provided their vessels display registration numbers issued by the Naval Submarine Base, New... above, providing: (i) The Commanding Officer, Naval Submarine Base New London, and the Coast...

  6. The New Education and the Institute of Education, University of London, 1919-1945

    ERIC Educational Resources Information Center

    Aldrich, Richard

    2009-01-01

    The London Day Training College (LDTC), founded in 1902, soon became the leading institution for the study of education and for the training of teachers in England. In 1932 it was transmuted into the Institute of Education of the University of London. Its title and pre-eminence have continued to this day. In the period 1919-1945 it was closely,…

  7. Schools Library Services: Their Changing Value to the Education of London's Children

    ERIC Educational Resources Information Center

    Collins, Judith

    2005-01-01

    In the history of education Schools Library Services are relative newcomers. The London County Council and its successor, the Inner London Education Authority, developed Schools Library Services for their own schools from the 1950s onwards. After the Education Reform Act 1988 became law, responsibility for education passed to the inner London…

  8. Diversity in Adoption of Linguistic Features of London English by Chinese and Bangladeshi Adolescents

    ERIC Educational Resources Information Center

    Pennington, Martha C.; Lau, Lawrence; Sachdev, Itesh

    2011-01-01

    This comparative study, conducted in multicultural London, investigates the occurrence in interviews with a researcher and in constructed same-sex peer conversations of five linguistic features characteristic of London English in the speech of two groups of British-born adolescents: ethnic Bangladeshis and ethnic Chinese of Cantonese heritage. The…

  9. 33 CFR 334.75 - Thames River, Naval Submarine Base New London, restricted area.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Base New London, restricted area. 334.75 Section 334.75 Navigation and Navigable Waters CORPS OF....75 Thames River, Naval Submarine Base New London, restricted area. (a) The area: The open waters of... channel to a point located at latitude 41°24′04.1″ N, longitude 72°05′51.2″ W then southerly along...

  10. 33 CFR 334.75 - Thames River, Naval Submarine Base New London, restricted area.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Base New London, restricted area. 334.75 Section 334.75 Navigation and Navigable Waters CORPS OF....75 Thames River, Naval Submarine Base New London, restricted area. (a) The area: The open waters of... channel to a point located at latitude 41°24′04.1″ N, longitude 72°05′51.2″ W then southerly along...

  11. 33 CFR 334.75 - Thames River, Naval Submarine Base New London, restricted area.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Base New London, restricted area. 334.75 Section 334.75 Navigation and Navigable Waters CORPS OF....75 Thames River, Naval Submarine Base New London, restricted area. (a) The area: The open waters of... channel to a point located at latitude 41°24′04.1″ N, longitude 72°05′51.2″ W then southerly along...

  12. 33 CFR 334.75 - Thames River, Naval Submarine Base New London, restricted area.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Thames River, Naval Submarine....75 Thames River, Naval Submarine Base New London, restricted area. (a) The area: The open waters of... notified by personnel of the New London Submarine Base that such use will interfere with...

  13. Psychoanalysis of Jack London's "The Call of the Wild" and "White Fang"

    ERIC Educational Resources Information Center

    Yang, Hongyan

    2015-01-01

    "The Call of the Wild" and "White Fang" both are masterpieces of Jack London. The protagonists Buck and White Fang are the incarnation of Jack himself to some extent for the two novels reveal a great deal of the writer. This essay aims at psychoanalyzing Jack London's creative process, the Oedipus complex and the confliction…

  14. Challenges faced when using radiocarbon measurements to estimate fossil fuel emissions in the UK.

    NASA Astrophysics Data System (ADS)

    Wenger, A.; O'Doherty, S.; Rigby, M. L.; Ganesan, A.; Manning, A.; Allen, G.

    2015-12-01

    Estimating the anthropogenic component of carbon dioxide emissions from direct atmospheric measurements is difficult, due to the large natural carbon dioxide fluxes. One way of determining the fossil fuel component of atmospheric carbon dioxide is the use of radiocarbon measurements. Whilst carbon reservoirs with a reasonably fast carbon exchange rate all have a similar radiocarbon content, fossil fuels are completely devoid of radiocarbon due to their age. Previous studies have 14CO2 (UK) this approach is compromised by the high density of 14CO2 emitting nuclear power plants. Of the 16 nuclear reactors in the UK, 14 are advanced gas cooled reactors, which have one of the highest 14CO2 emission rates of all reactor types. These radiocarbon emissions not only lead to a serious underestimation of the recently added fossil fuel CO2, by masking the depletion of 14C in CO2, but can in fact overshadow the depletion by a factor of 2 or more. While a correction for this enhancement can be applied, the emissions from the nuclear power plants are highly variable, and an accurate correction is therefore not straightforward. We present the first attempt to quantify UK fossil fuel CO2 emissions through the use of 14CO2. We employ a sampling strategy that makes use of a Lagrangian particle dispersion model, in combination with nuclear industry emission estimates, to forecast "good" sampling times, in an attempt to minimize the correction due to emissions from the nuclear industry. As part of the Greenhouse gAs Uk and Global Emissions (GAUGE) project, 14CO2measurements are performed at two measurement sites in the UK and Ireland, as well as during science flights around the UK. The measurement locations have been chosen with a focus on high emitting regions such as London and the Midlands. We discuss the unique challenges that face the determination of fossil fuel emissions through radiocarbon measurements in the UK and our sampling strategy to deal with them. In addition we

  15. Challenges in researching migration status, health and health service use: an intersectional analysis of a South London community

    PubMed Central

    Gazard, Billy; Frissa, Souci; Nellums, Laura; Hotopf, Matthew; Hatch, Stephani L.

    2015-01-01

    Objectives. This study aimed to investigate the associations between migration status and health-related outcomes and to examine whether and how the effect of migration status changes when it is disaggregated by length of residence, first language, reason for migration and combined with ethnicity. Design. A total of 1698 adults were interviewed from 1076 randomly selected households in two South London boroughs. We described the socio-demographic and socio-economic differences between migrants and non-migrants and compared the prevalence of health-related outcomes by migration status, length of residence, first language, reason for migration and migration status within ethnic groups. Unadjusted models and models adjusted for socio-demographic and socio-economic indicators are presented. Results. Migrants were disadvantaged in terms of socio-economic status but few differences were found between migrant and non-migrants regarding health or health service use indicators; migration status was associated with decreased hazardous alcohol use, functional limitations due to poor mental health and not being registered with a general practitioner. Important differences emerged when migration status was disaggregated by length of residence in the UK, first language, reason for migration and intersected with ethnicity. The association between migration status and functional limitations due to poor mental health was only seen in White migrants, migrants whose first language was not English and migrants who had moved to the UK for work or a better life or for asylum or political reasons. There was no association between migration status and self-rated health overall, but Black African migrants had decreased odds for reporting poor health compared to their non-migrant counterparts [odds ratio = 0.15 (0.05–0.48), p < 0.01]. Conclusions. Disaggregating migration status by length of residence, first language and reason for migration as well as intersecting it with ethnicity leads

  16. Dr. William Briggs: ophthalmic physician at St. Thomas' Hospital, London.

    PubMed

    Winstanley, J

    2001-01-01

    William Briggs, MD, established himself as one of the first ophthalmic physicians, whom today we would call a neuro-ophthalmologist, to practice in the United Kingdom. After graduating with an MD from Cambridge in 1677, and while a Fellow of Corpus Christi College, he carried out original studies in visual anatomy and physiology. He described and named the optic papilla and the retinal nerve fibers in his book Ophthalmographia, published in 1676. He published his New Theory of Vision in 1682. While at Cambridge, he was a contemporary and a friend of Isaac Newton, with whom Briggs worked but who, in matters of visual anatomy and physiology, came to reach different conclusions from Briggs. In 1683, Briggs came to London to practice as a physician at St. Thomas' Hospital, where he established a considerable reputation as an ophthalmologist. For political reasons he was forced to resign from the Hospital prematurely.

  17. Interoceptive Ability Predicts Survival on a London Trading Floor

    PubMed Central

    Kandasamy, Narayanan; Garfinkel, Sarah N.; Page, Lionel; Hardy, Ben; Critchley, Hugo D.; Gurnell, Mark; Coates, John M.

    2016-01-01

    Interoception is the sensing of physiological signals originating inside the body, such as hunger, pain and heart rate. People with greater sensitivity to interoceptive signals, as measured by, for example, tests of heart beat detection, perform better in laboratory studies of risky decision-making. However, there has been little field work to determine if interoceptive sensitivity contributes to success in real-world, high-stakes risk taking. Here, we report on a study in which we quantified heartbeat detection skills in a group of financial traders working on a London trading floor. We found that traders are better able to perceive their own heartbeats than matched controls from the non-trading population. Moreover, the interoceptive ability of traders predicted their relative profitability, and strikingly, how long they survived in the financial markets. Our results suggest that signals from the body - the gut feelings of financial lore - contribute to success in the markets. PMID:27641692

  18. The prevalence of cervical ribs in a London population.

    PubMed

    Brewin, James; Hill, Martin; Ellis, Harold

    2009-04-01

    Cervical ribs are an important cause of neurovascular compression at the thoracic outlet. Previous studies have shown the prevalence of cervical ribs to be between 0.05 and 3%, depending on the sex and race of the population studied. We examined 1,352 chest radiographs to determine the prevalence of cervical ribs in a London population of mixed sex and ethnicity. Our study found that the overall prevalence of cervical ribs was 0.74% with a higher rate in females compared with males (1.09 and 0.42%, respectively). Of the 10 individuals with a cervical rib, five were on the left, three were on the right and two were bilateral. The presence of elongated C7 transverse processes (transverse apophysomegaly) was also noted. We found a total of 30 elongated transverse processes with an overall prevalence of 2.21%. They were also more common in females (3.43%) than males (1.13%).

  19. Cost benefit analysis of 20 mph zones in London.

    PubMed

    Steinbach, Rebecca; Cairns, John; Grundy, Chris; Edwards, Phil

    2013-06-01

    Evidence suggests that 20 mph zones are an effective intervention to reduce casualties from road traffic crashes in urban areas. This analysis compares the costs of construction of the 20 mph zone intervention in high and low casualty areas in London to the value of casualties avoided over 5 and 10 year time horizons. Probabilistic sensitivity analyses were conducted to quantify uncertainty in the results associated with model parameters. Results indicate a net present value (NPV) of £18 947 (90% credible limits -£75 252 to £82 021 2005 prices) after 5 years and £67 306 (£-29 157 to £137 890) after 10 years when 20 mph zones are implemented in areas with one or more casualty per kilometre of road. Simulations from our model suggest that the 'threshold of casualties' where NPVs become positive using a 10 year time horizon is 0.7 casualties per kilometre.

  20. Interoceptive Ability Predicts Survival on a London Trading Floor.

    PubMed

    Kandasamy, Narayanan; Garfinkel, Sarah N; Page, Lionel; Hardy, Ben; Critchley, Hugo D; Gurnell, Mark; Coates, John M

    2016-09-19

    Interoception is the sensing of physiological signals originating inside the body, such as hunger, pain and heart rate. People with greater sensitivity to interoceptive signals, as measured by, for example, tests of heart beat detection, perform better in laboratory studies of risky decision-making. However, there has been little field work to determine if interoceptive sensitivity contributes to success in real-world, high-stakes risk taking. Here, we report on a study in which we quantified heartbeat detection skills in a group of financial traders working on a London trading floor. We found that traders are better able to perceive their own heartbeats than matched controls from the non-trading population. Moreover, the interoceptive ability of traders predicted their relative profitability, and strikingly, how long they survived in the financial markets. Our results suggest that signals from the body - the gut feelings of financial lore - contribute to success in the markets.

  1. Brachial plexus injury: the London experience with supraclavicular traction lesions.

    PubMed

    Birch, Rolfe

    2009-01-01

    In this article, the author details the experiences of his hospital and other London hospitals in treating brachial plexus injury. As noted, important advances have been made in methods of diagnosis and repair. Myelography was replaced by CT scan and later by MRI. Among the topics the author explores are diagnosis (including pain, the presence or absence of the Tinel sign, and the irradiation of pins and needles) and the principles of repair. The author emphasizes that it is imperative that ruptured nerves be repaired as soon as possible, with the closed traction lesion coming, in urgency, close behind reattachment of the amputated hand or repair of a great artery and a trunk nerve in the combined lesion. Finally, the article concludes that the surgeon must be actively engaged in the whole process of rehabilitation and treatment of pain. This is part of a Point-Counterpoint discussion with Dr. David G. Kline's presentation of "A Personal Experience."

  2. European Society of Cardiology (ESC) Congress Report from London 2015.

    PubMed

    Nishiguchi, Tsuyoshi; Akasaka, Takashi

    2015-01-01

    The Annual Congress of the European Society of Cardiology (ESC) was held in London from 29 August to 2 September 2015. It is the leading conference in cardiology in the world, with presentations on the latest scientific discoveries, innovations, technology, education, and clinical practices. More than 32,000 delegates and 5,000 exhibitors from 140 countries participated, sharing a number of scientific presentations, including 28 clinical hot lines, 18 clinical trial updates, 20 registry studies, 12 basic and translational science hot line studies, and 4,533 abstract studies. Japan had the highest number of accepted abstracts at the Congress, indicating the great contribution of Japanese scientists and the Japanese Circulation Society.

  3. Are inner-cities bad for your health? Comparisons of residents' and third parties' perceptions of the urban neighbourhood of Gospel Oak, London.

    PubMed

    Whitley, Rob; Prince, Martin

    2005-01-01

    This paper analyses representations of the neighbourhood of Gospel Oak (London, UK), by contrasting views of residents with views expressed by third parties. Data from residents were gathered through in-depth qualitative methods. Data from third parties were gathered through documentary analysis. Third parties' descriptions of Gospel Oak were significantly more negative than residents'. In contrast, residents were overwhelmingly positive about the neighbourhood, often taking a diametrically opposed view to third parties on the same factor, for example, quality of housing. We argue that third parties' negative social construction of Gospel Oak is functional rather than descriptive; a pathological orientation is usually taken to assist efforts to win regeneration funding. Though this is sometimes successful, we discuss possible negative affects of this social construction, for example, stigmatisation. Finally, we warn against making assumptions of collective social and physical pathology in urban neighbourhoods, urging a more critical approach to the study of the inner-city in the health sciences.

  4. Sustaining International CBRN Centers of Excellence with a Focus on Nuclear Security and Safeguards: Initial Scoping Session London, 23-24 September 2013 SUMMARY REPORT

    SciTech Connect

    Anderson, Roger G.; Frazar, Sarah L.

    2013-12-12

    This report provides a summary-level description of the key information, observations, ideas, and recommendations expressed during the subject meeting. The report is organized to correspond to the meeting agenda provided in Appendix 1 and includes references to several of the participants listed in Appendix 2 .The meeting venue was Lloyd’s Register in the City of London. Lloyd’s Register graciously accommodated the request of The Pacific Northwest Laboratory (PNNL) with whom it works on various safeguards activities commissioned by NNSA. PNNL and NNSA also shared the goal of the meeting/study with the United Kingdom (UK) Foreign and Commonwealth Office (FCO) and the Department of Energy and Climate Change with whom they coordinated the participant list.

  5. SETI and astrobiology: The Rio Scale and the London Scale

    NASA Astrophysics Data System (ADS)

    Almár, Iván

    2011-11-01

    The public reaction to a discovery, the character of the corresponding risk communication, as well as the possible impact on science and society all depend on the character of the phenomenon discovered, on the method of discovery, on the distance to the phenomenon and, last but not least, on the reliability of the announcement itself. The Rio Scale - proposed together with Jill Tarter just a decade ago at an IAA symposium in Rio de Janeiro - attempts to quantify the relative importance of such a “low probability, high consequence event”, namely the announcement of an ETI discovery. After the publication of the book “The Eerie Silence” by Paul Davies it is necessary to control how the recently suggested possible “technosignatures” or “technomarkers” mentioned in this book could be evaluated by the Rio Scale. The new London Scale, proposed at the Royal Society meeting in January 2010, in London, is a similar attempt to quantify the impact of an announcement regarding the discovery of ET life on an analogous ordinal scale between zero and ten. Here again the new concept of a “shadow biosphere” raised in this book deserves a special attention since a “weird form of life” found on Earth would not necessarily have an extraterrestrial origin, nevertheless it might be an important discovery in itself. Several arguments are presented that methods, aims and targets of “search for ET life” and “search for ET intelligence” are recently converging. The new problem is raised whether a unification of these two scales is necessary as a consequence of the convergence of the two subjects. Finally, it is suggested that experts in social sciences should take the structure of the respective scales into consideration when investigating case by case the possible effects on the society of such discoveries.

  6. Lichen and bryophyte distribution on oak in London in relation to air pollution and bark acidity.

    PubMed

    Larsen, R S; Bell, J N B; James, P W; Chimonides, P J; Rumsey, F J; Tremper, A; Purvis, O W

    2007-03-01

    Epiphytic lichen and bryophyte distribution and frequency were investigated on the trunks of 145 young oak trees throughout London and surrounding counties, and compared with pollution levels and bark pH. Sixty-four lichen and four bryophyte species were recorded. Three major zones were identified: (i) two central regions with a few lichens, bryophytes absent; (ii) a surrounding region with a more diverse flora including a high cover of nitrophyte lichens; and (iii) an outer region, characterised by species absent from central London, including acidophytes. Nineteen species were correlated with nitrogen oxides and 16 with bark pH, suggesting that transport-related pollution and bark acidity influence lichen and bryophyte distribution in London today. Lichens and bryophytes are responding to factors that influence human and environmental health in London. Biomonitoring therefore has a practical role to assess the effects of measures to improve London's air quality.

  7. Community Engagement using World Café: The Well London Experience

    PubMed Central

    Sheridan, Kevin; Adams-Eaton, Faye; Trimble, Allison; Renton, Adrian; Bertotti, Marcello

    2016-01-01

    The Well London programme was launched across twenty boroughs in London during late 2007 to improve the health and well-being of residents living in some of the most deprived communities in London. Well London employed a multi-stage community engagement process which informed the overall project strategy for each intervention area. In this article we establish and describe the key principles that guided the design of this innovative community engagement process. Principles included building collaborative partnerships, working with whole-systems, privileging community knowledge and working with the deficit of experience in each area. The article then describes in detail how these principles were operationalised throughout the preparation and delivery of forty World Cafes, which were the first open community activities of the Well London community engagement process. Finally, this article reflects on and summarises the lessons learned when employing innovative, inclusive and transparent community engagement for health promotion. PMID:27857453

  8. Science education reforms in the UK.

    PubMed

    2012-10-01

    As children return to school at the end of the summer in the UK, planned reforms aim to increase their science and maths literacy. A comprehensive foundation in these essential subjects is necessary to ensure that the UK remains at the forefront of science and technology for decades to come.

  9. Leadership Practices in German and UK Organisations

    ERIC Educational Resources Information Center

    McCarthy, Grace

    2005-01-01

    Purpose: The aim of this research was to determine whether leadership practices vary between German and UK organisations. Design/methodology/approach: The author used self-assessment documents submitted by German and UK organisations to the European Foundation for Quality Management (EFQM), to identify leadership practices in both countries. A…

  10. UK Policy on Folate Fortification of Foods

    ERIC Educational Resources Information Center

    Malcolm, Alan

    2004-01-01

    The UK Food Standards Agency has decided not to recommend fortification of foods with folate, the family of vitamins associated with the prevention of neural tube defects in babies. This is a change in attitude from previous recommendations made by a series of committees and reports in the UK. Notably, it differs from US policy on the matter. The…

  11. Recent TB transmission, clustering and predictors of large clusters in London, 2010–2012: results from first 3 years of universal MIRU-VNTR strain typing

    PubMed Central

    Hamblion, Esther L; Le Menach, Arnaud; Anderson, Laura F; Lalor, Maeve K; Brown, Tim; Abubakar, Ibrahim; Anderson, Charlotte; Maguire, Helen; Anderson, Sarah R

    2016-01-01

    Background The incidence of TB has doubled in the last 20 years in London. A better understanding of risk groups for recent transmission is required to effectively target interventions. We investigated the molecular epidemiological characteristics of TB cases to estimate the proportion of cases due to recent transmission, and identify predictors for belonging to a cluster. Methods The study population included all culture-positive TB cases in London residents, notified between January 2010 and December 2012, strain typed using 24-loci multiple interspersed repetitive units-variable number tandem repeats. Multivariable logistic regression analysis was performed to assess the risk factors for clustering using sociodemographic and clinical characteristics of cases and for cluster size based on the characteristics of the first two cases. Results There were 10 147 cases of which 5728 (57%) were culture confirmed and 4790 isolates (84%) were typed. 2194 (46%) were clustered in 570 clusters, and the estimated proportion attributable to recent transmission was 34%. Clustered cases were more likely to be UK born, have pulmonary TB, a previous diagnosis, a history of substance abuse or alcohol abuse and imprisonment, be of white, Indian, black-African or Caribbean ethnicity. The time between notification of the first two cases was more likely to be <90 days in large clusters. Conclusions Up to a third of TB cases in London may be due to recent transmission. Resources should be directed to the timely investigation of clusters involving cases with risk factors, particularly those with a short period between the first two cases, to interrupt onward transmission of TB. PMID:27417280

  12. Impact of HIV on adult (15-54) mortality in London: 1979-96

    PubMed Central

    Hickman, M.; Bardsley, M.; De Angelis, D.; Ward, H.

    1999-01-01

    OBJECTIVE: To describe the impact of HIV on mortality in men and women aged 15-54 in London. DESIGN: Combination of routine mortality statistics with reports of AIDS deaths adjusted for underreporting and change in address from time of report to time of death. Calculation of standardised mortality ratios (SMRs) for males including and excluding HIV comparing inner London and outer London with the rest of England and Wales. METHODS: Comparison of trends in all cause mortality and SMRs in males over time. Comparison of trends in HIV related deaths with other main causes of deaths in males and females in London. RESULTS: Age standardised rates for the rest of England and Wales showed a continual decline from 1979 to 1996 but rates in inner London males (ages 15-54) stopped declining around 1984-5 leading to a considerable increase in the SMR for inner London from 127 for 1985-7 to 171 for 1994-6. SMRs excluding HIV related deaths for inner London, however, showed no significant change over this time. There was a fall in HIV related mortality in 1996, though HIV was still the leading cause of death in males and second leading cause of death in females in inner London, and the fourth commonest cause of death in males in outer London. CONCLUSION: These data are the first to indicate the impact of HIV on mortality within a significant population in England and Wales. They show that public health priorities in London are different from the rest of the country. Analyses of trends of all cause mortality in people under 65 may mislead unless they take account of HIV. 


 PMID:10754940

  13. The impact of migration on the sexual health, behaviours and attitudes of Central and East European gay/bisexual men in London

    PubMed Central

    Mole, Richard C.M.; Parutis, Violetta; Gerry, Christopher J.; Burns, Fiona M.

    2013-01-01

    Background Building on an earlier quantitative study which found that gay/bisexual men from Central and Eastern Europe were at greater risk of sexual ill health following migration to the UK, the aim of this qualitative study is to explore how the process of migration itself may have influenced the migrants’ sexual behaviour and attitudes. Methods To address these questions, we conducted 17 in-depth interviews in London with gay/bisexual male migrants from Central and Eastern Europe, drawing on Fisher and Fisher's Information-Motivation-Behavioral Skills model as an interpretive framework. Results We find that the sexual behaviours of our respondents have been significantly influenced by the process of migration itself. In particular, extricating themselves from the traditional systems of social control in their home societies and having greater access to gay venues in London resulted in their increased sexual activity, particularly in the first phase of migration. High-risk sexual behaviour was found to be a factor of sexual mixing, the use of commercial sex and perceptions of risk in the UKvis-á-vis Central and Eastern Europe, with each of these factors also influenced by the process of migration. Risk-prevention behaviour depended upon the possession of appropriate risk-prevention information, motivation to use condoms and appropriate behavioural skills, with the latter two factors in particular influenced by social mores in the home country and the UK. Conclusions The interviews suggested a number of migration-related factors that increased the STI and HIV risk for these migrants. A number of potentially important policy recommendations stem from our analysis. PMID:23597207

  14. Post-migration geographical mobility, mental health and health service utilisation among Somali refugees in the UK: a qualitative study.

    PubMed

    Warfa, Nasir; Bhui, Kamaldeep; Craig, Tom; Curtis, Sarah; Mohamud, Salaad; Stansfeld, Stephen; McCrone, Paul; Thornicroft, Graham

    2006-12-01

    Migration is known to be associated with poor health outcomes for certain marginalised and socially disadvantaged populations. This paper reviews a number of reasons why residential mobility in the 'host' country may be associated with poor mental health for refugee populations and reports on a qualitative study of Somalis living in London, UK, and their beliefs about the relationship between residential mobility, poor health and health service use. Two discussion groups were undertaken with 13 Somali professionals and four groups with 21 lay Somalis in East and South London, UK. Lay Somalis did not wish to move accommodation but felt they were forced to move. Some Somali professionals believed that the nomadic history of Somalis made them more likely to elect to move in order to escape problems of living, but this was not supported by the lay group. Frequent geographical movements were seen as stressful and undesirable, disrupted family life and child development and were detrimental to well being. Residential mobility was also perceived to interfere with health care receipt and therefore should be more comprehensively assessed in larger quantitative studies.

  15. Trends in the stem cell and regenerative medicine industry.

    PubMed

    Ilic, Dusko

    2012-09-01

    The World Stem Cell Regenerative Medicine Congress series, now in its 7th year, is organized annually in the USA, Europe and Asia by Terrapinn, a business media company with its head office in London, and has grown over the last several years into the largest and probably the most important strategic stem cell conference where regulators, investors, big pharma, and small and medium enterprises gather to share and create synergy in developing and commercializing stem cell applications. The conference, held in London on 21-23 May 2012, only confirmed that this series is the meeting to attend if you want to get a clear understanding of trends in the stem cell and regenerative medicine industry.

  16. Impact of Waterpipe Tobacco Pack Health Warnings on Waterpipe Smoking Attitudes: A Qualitative Analysis among Regular Users in London

    PubMed Central

    Jawad, Mohammed; Bakir, Ali; Ali, Mohammed; Grant, Aimee

    2015-01-01

    Background. Despite the rise in prevalence of waterpipe tobacco smoking, it has received little legislative enforcement from governing bodies, especially in the area of health warning labels. Methods. Twenty regular waterpipe tobacco smokers from London took part in five focus groups discussing the impact of waterpipe tobacco pack health warnings on their attitudes towards waterpipe smoking. We presented them with existing and mock waterpipe tobacco products, designed to be compliant with current and future UK/EU legislation. Data were analysed using thematic analysis. Results. Participants felt packs were less attractive and health warnings were more impactful as health warnings increased in size and packaging became less branded. However, participants highlighted their lack of exposure to waterpipe tobacco pack health warnings due to the inherent nature of waterpipe smoking, that is, smoking in a café with the apparatus already prepacked by staff. Health warnings at the point of consumption had more reported impact than health warnings at the point of sale. Conclusions. Waterpipe tobacco pack health warnings are likely to be effective if compliant with existing laws and exposed to end-users. Legislations should be reviewed to extend health warning labels to waterpipe accessories, particularly the apparatus, and to waterpipe-serving premises. PMID:26273642

  17. Evaluation of needle exchange in central London: behaviour change and anti-HIV status over one year.

    PubMed

    Hart, G J; Carvell, A L; Woodward, N; Johnson, A M; Williams, P; Parry, J V

    1989-05-01

    From November 1987 to October 1988, numbers of clients, visits made and syringes dispensed and returned were monitored at the needle exchange of the Middlesex Hospital, London, UK. A sample of clients were interviewed 1 month after entry to the scheme and again 3 months later to evaluate changes in injecting and sexual risk behaviours for HIV infection. Clients were asked to donate saliva for anti-HIV immunoglobulin G (IgG) antibody capture radioimmunoassay (GACRIA). The rate of lending and borrowing used injecting equipment fell, both compared with rates prior to entry to the scheme and during the period of study. Frequency of injecting did not increase and there was reduced incidence of abscesses. There was a highly significant correlation between multiple sexual partners and condom use and a reduction in the proportion of clients with multiple partners. On entry to the study, seven out of 121 (6%) clients were anti-HIV positive; after 3 months, a further two clients tested were found to be anti-HIV positive. Anti-HIV positivity prevalence for the year of study was nine out of 121 (7%). The scheme attracts clients, reduces injecting-related risk for HIV infection and has high equipment return rates. Saliva testing is acceptable to clients. Continued monitoring of anti-HIV in saliva is indicated.

  18. Measurement of NOx fluxes by eddy covariance from the BT tower, London during the ClearfLo project

    NASA Astrophysics Data System (ADS)

    Lee, James; Helfter, Carole; Nemitz, Eiko; Tremper, Anja; Stocker, Jenny; Carruthers, David

    2014-05-01

    The vast majority of air pollutants are emitted directly into the atmosphere from activities occurring at the Earth's surface. One of the key anthropogenic pollutants is NOx (defined as the sum of NO and NO2), which is emitted as a result of most anthropogenic combustion processes. Whilst the chemical reactions and atmospheric processing of NOx are reasonably well understood, and can be modelled with some skill, large uncertainties arise in models due to uncertainty associated with the rate of emissions. In recent years it has become clear that measured trends in certain pollutants, for example NO2, have not followed trends predicted by inventories. Continued exceedances of certain air pollution targets are of significant concern to governments, who have identified reducing this uncertainty associated with emissions as key evidence need. As part of the UK Natural Environment Research Council (NERC) Clean Air for London (ClearfLo) project, concentrations and fluxes of NOx were measured from the top of the BT tower, which is a 188m high telecommunications tower, situated in central London (51o31'17.4'N; 0o8'20.04W). The tower is surrounded by a mixture of commercial and residential buildings with an average height of 15 m. The typical daytime flux footprint of the tower is dominated by commercial/residential buildings and roads (82%) but also includes urban parkland (13%) and impervious ground (5%). High time resolution (10 Hz) chemiluminescence measurements of NO and NO2 (photolytic conversion to NO followed by chemiluminescence) were combined with fast turbulence measurements from a sonic anemometer to calculate fluxes using the eddy covariance technique. In brief, NOx fluxes per notional half-hourly averaging period were obtained by maximising the covariance between instantaneous (i.e. mean for the averaging period subtracted from each 10 Hz data point) fluctuations of NOx mixing ratio and vertical wind velocity. 24 hour NOx flux measurements were made on 36 days

  19. [Expedition medicine].

    PubMed

    Donlagić, Lana

    2009-01-01

    Expedition and wildeness medicine is a term that combines rescue medicine, sport medicine as well as more specific branches as polar or high altitude medicine. It is being intensively studied both at the reaserch institutes and on expeditions. Ophtalmologists are concentrated on the reaserch of HARH (High Altitude Retinal Hemorrhage), neurologists on HACE reaserch (High Altitude Cerebral Edema), psychologists are developing tests to decsribe cognitive functions and many physicians are being trained to work in extreme enviroment. The result of all this effort are numerous new findings in pathophysiology and therapy of altitude illness, increased security on expedition and further development of expeditionism.

  20. Use Medicines Safely

    MedlinePlus

    ... Medicines Safely Print This Topic En español Use Medicines Safely Browse Sections The Basics Overview Prescription Medicines ... Medicines 1 of 7 sections The Basics: Prescription Medicines There are different types of medicine. The 2 ...

  1. Pharmaceutical innovation by the seven UK-owned pharmaceutical companies (1964-1985).

    PubMed Central

    Prentis, R A; Lis, Y; Walker, S R

    1988-01-01

    1 A total of three hundred and nineteen new chemical entities (NCEs) were investigated in man for the first time between 1964 and 1985 by seven UK-owned pharmaceutical companies. The majority (96.2%), were self-originated by the UK company or one of its overseas subsidiaries. 2 There was an increase in the number of NCEs investigated each year in man, doubling from an average of 12 per year up to 1980, to over 20 per year between 1981 and 1985. The majority of first drug evaluations in human volunteers were carried out in the UK (92.2%), in contrast to evaluation of new medicines in patients, where 42.9% were first tested outside the UK. 3 The majority of NCEs evaluated in man (78%), were in four therapeutic classes: anti-infectives (32%), anti-allergics (22%), drugs acting on the central nervous system (13%) and cardiovascular system agents (11%). 4 By the end of 1985, 49 (15.4%) of these NCEs had been marketed in the UK and 198 (62.0%) discontinued from further development. The main reasons for termination were inappropriate pharmacokinetics in man (39.4%), and lack of clinical efficacy (29.3%). 5 Average development times increased from less than 2 years between 1964 and 1965, to around 8 years in the 1980s with a consequent reduction in the effective patent life. PMID:3358900

  2. Anthropogenic greenhouse gas contribution to UK autumn flood risk

    NASA Astrophysics Data System (ADS)

    Pall, Pardeep; Aina, Tolu; Stone, Dáithí; Stott, Peter; Nozawa, Toru; Hilberts, Arno; Lohmann, Dag; Allen, Myles

    2010-05-01

    climate model adequately represents autumn synoptic conditions, and that our precipitation-runoff model adequately represents England & Wales runoff variability. Moreover, our model results indicate 20th century anthropogenic greenhouse gas emissions significantly (at the 10% level) increased England & Wales flood risk in Autumn 2000 and most probably about trebled it. This pilot demonstration of the Probabilistic Event Attribution framework forms the foundation for an ongoing long-term project to provide operational attribution statements for extreme weather-related events worldwide. References: -------------- 1. Hegerl, G.C. et al. Understanding and attributing climate change. In Climate change 2007: The physical science basis. Contribution of Working Group I to the Fourth Assessment Report of the Intergovernmental Panel on Climate Change [eds Solomon, S. et al.] (Cambridge University Press, United Kingdom and New York, NY, USA) (2007). 2. Stott, P.A. et al. Detection and attribution of climate change: a regional perspective. Wiley Interdisciplinary Reviews: Climate Change, submitted. 3. Alexander, L.V. & Jones, P.D. Updated precipitation series for the U.K. and discussion of recent extremes. Atmos. Sci. Lett. 1, 142-150 (2001). 4. Marsh, T.J. & Dale, M. The UK floods of 2000-2001 : A hydrometeorological appraisal. J. Chartered Inst. Water Environ. Manage. 16, 180-188 (2002). 5. Association of British Insurers. Flooding: A partnership approach to protecting people. http://www.abi.org.uk/Display/File/301/Flooding_-_A_Partnership_Approach_to_Protecting_People.doc (2001). 6. Department for Environment, Food and Rural Affairs. To what degree can the October/November 2000 flood events be attributed to climate change? DEFRA FD2304 Final Report, London, 36 pp. (2001). 7. Environment Agency. Lessons learned: Autumn 2000 floods. Environment Agency, Bristol, 56 pp. (2001). 8. Allen, M.R. Liability for climate change. Nature 421, 891-892 (2003). 9. Stone, D.A. & Allen, M.R. The

  3. Vulnerable Medicine

    ERIC Educational Resources Information Center

    Bochner, Arthur P.

    2009-01-01

    In "Narrative Medicine: Honoring the Stories of Illness," Rita Charon paints an original and humane portrait of what it can mean to be a doctor, to live a life immersed in sickness and dedicated to wellness. Charon drops the veil, inviting readers to look at the secret, subjective, emotional face of medicine, a zone of self-censored feelings and…

  4. Behavioral Medicine.

    ERIC Educational Resources Information Center

    Garfield, Sol L., Ed.

    1982-01-01

    Contains 18 articles discussing the uses of behavioral medicine in such areas as obesity, smoking, hypertension, and headache. Reviews include discussions of behavioral medicine and insomnia, chronic pain, asthma, peripheral vascular disease, and coronary-prone behavior. Newly emerging topics include gastrointestinal disorders, arthritis,…

  5. Aerospace Medicine

    NASA Technical Reports Server (NTRS)

    Davis, Jeffrey R.

    2006-01-01

    This abstract describes the content of a presentation for ground rounds at Mt. Sinai School of Medicine. The presentation contains three sections. The first describes the history of aerospace medicine beginning with early flights with animals. The second section of the presentation describes current programs and planning for future missions. The third section describes the medical challenges of exploration missions.

  6. [Sport medicine].

    PubMed

    Epstein, Yoram

    2012-02-01

    It is only since the late 20th century that Sport and Exercise Medicine has emerged as a distinct entity in health care. In Israel, sports medicine is regulated by a State Law and a sport physician is certified after graduating a structured program. In the past, sports medicine was related to the diagnosis and treatment of injuries encountered by top athletes. In recent years, the scope of sport medicine has broadened to reflect the awareness of modern society of the dangers of physical inactivity. In this perspective the American College of Sport Medicine (ACSM) recently launched a program--"Exercise is Medicine", to promote physical activity in order to improve health and well-being and prevention of diseases through physical activity prescriptions. This program is from doctors and healthcare providers, adjusted to the patient or trainee. The sport physician does not replace a medical specialist, but having a thorough understanding about the etiology of a sport-related injury enables him to better focus on treatment and prevention. Therefore, Team Physicians in Elite Sport often play a role regarding not only the medical care of athletes, but also in the physiological monitoring of the athlete and correcting aberrations, to achieve peak physical performance. The broad spectrum of issues in sport and exercise medicine cannot be completely covered in one issue of the Journal. Therefore, the few reports that are presented to enhance interest and understanding in the broad spectrum of issues in sports and exercise medicine are only the tip of the iceberg.

  7. Samuel Holden Parsons Lee (1772-1863): American physician, entrepreneur and selfless fighter of the 1798 Yellow Fever epidemic of New London, Connecticut.

    PubMed

    Mattie, James K; Desai, Sukumar P

    2015-02-01

    Samuel Holden Parsons Lee practised medicine at a time when the germ theory of disease had not yet been proposed and antibiotics remained undiscovered. In 1798 he served selflessly as the only physician in town who was willing to battle the Yellow Fever outbreak of New London, Connecticut. Because he practised at the dawn of the age of patent medicine, unfortunately his name also came to be associated with medical quackery. We argue that his contributions have been grossly underestimated. He compounded and vended medications - including bilious pills and bitters - that were gold standards of the day. Moreover, one preparation for treatment of kidney stones led to his sub-specialization in this field and was met with such success that its sale continued for nearly 100 years after his death. While a talented medical man, Lee also had a knack for business, finding success in trading, whaling and real estate.

  8. Prevalence of adult Huntington's disease in the UK based on diagnoses recorded in general practice records

    PubMed Central

    Evans, Stephen JW; Douglas, Ian; Rawlins, Michael D; Wexler, Nancy S; Tabrizi, Sarah J; Smeeth, Liam

    2013-01-01

    Background and purpose The prevalence of Huntington's disease (HD) in the UK is uncertain. Recently, it has been suggested that the prevalence may be substantially greater than previously reported. This study was undertaken to estimate the overall UK prevalence in adults diagnosed with HD, using data from primary care. Methods The electronic medical records of patients aged 21 years or more, with recorded diagnoses of HD, were retrieved from the UK's General Practice Research Database. Prevalence was estimated from the number of persons with recorded diagnoses of HD, on 1 July each year, between 1990 and 2010. This number was divided by the total number of persons registered with participating general practices on that same date. These data were also used to estimate both age specific prevalence and prevalence in various regions of the UK. Results A total of 1136 patients diagnosed with HD, aged 21 years or more, were identified from the database. The estimated prevalence (expressed per 100 000 population) rose from 5.4 (95% CI 3.8 to 7.5) in 1990 to 12.3 (95% CI 11.2 to 13.5) in 2010. Although an increased prevalence was observed within every age group, the most dramatic was in older patients. Age specific prevalence was highest in the 51–60 year age range (15.8 95% CI 9.0 to 22.3). The prevalence of adult HD was lowest in the London region (5.4 (95% CI 3.0 to 8.9)) and highest in the North East of England (18.3 (95% CI 8.6 to 34.6)) and Scotland (16.1 (95% CI 10.8 to 22.9)). Conclusions The prevalence of diagnosed HD is clearly substantially higher in the UK than suggested from previous studies. By extrapolation to the UK as a whole, it is estimated that there are more than 5700 people, aged 21 years or more, with HD. There has also been a surprising doubling of the HD population between 1990 and 2010. Many factors may have caused this increase, including more accurate diagnoses, better and more available therapies and an improved life expectancy

  9. A study of HIV positive undocumented African migrants' access to health services in the UK.

    PubMed

    Whyte, James; Whyte, Maria D; Hires, Kimberly

    2015-01-01

    Newly immigrated persons, whatever their origin, tend to fall in the lower socioeconomic levels. In fact, failure of an asylum application renders one destitute in a large proportion of cases, often resulting in a profound lack of access to basic necessities. With over a third of HIV positive failed asylum seekers reporting no income, and the remainder reporting highly limited resources, poverty is a reality for the vast majority. The purpose of the study was to determine the basic social processes that guide HIV positive undocumented migrant's efforts to gain health services in the UK. The study used the Grounded Theory Approach. Theoretical saturation occurred after 16 participants were included in the study. The data included reflections of the prominent factors related to the establishment of a safe and productive life and the ability of individuals to remain within the UK. The data reflected heavily upon the ability of migrants to enter the medical care system during their asylum period, and on an emerging pattern of service denial after loss on immigration appeal. The findings of this study are notable in that they have demonstrated sequence of events along a timeline related to the interaction between the asylum process and access to health-related services. The results reflect that African migrants maintain a degree of formal access to health services during the period that they possess legal access to services and informal access after the failure of their asylum claim. The purpose of this paper is to examine the basic social processes that characterize efforts to gain access to health services among HIV positive undocumented African migrants to the UK. The most recent estimates indicate that there are a total of 618,000 migrants who lack legal status within the UK. Other studies have placed the number of undocumented migrants within the UK in the range of 525,000-950,000. More than 442,000 are thought to dwell in the London metropolitan area. Even in

  10. Towards an operational lidar network across the UK

    NASA Astrophysics Data System (ADS)

    Adam, Mariana; Horseman, Andrew; Turp, Myles; Buxmann, Joelle; Sugier, Jacqueline

    2015-04-01

    The Met Office has been operating a ceilometer network since 2012. This network consists of 11 Jenoptik Nimbus ceilometers (operating at 1064 nm) and 32 Vaisala ceilometers (25 CL31, operating at 910 nm and 7 CT25 operating at 905 nm). The data are available in near real time (NRT) (15 min for Jenoptik and 1 h for Vaisala). In 2014, six additional stations from Met Éireann (Ireland) were added to the network (5 CL31 and 1 CT25). Visualisation of attenuated backscatter and cloud base height are available from http://www.metoffice.gov.uk/public/lidarnet/lcbr-network.html. The main customers are the Met Office Hazard Centre which provides a quick response to customers requiring forecast information to manage a wide variety of environmental incidents and the London Volcanic Ash Advisory Centre (VAAC), also based at the Met Office, which monitor volcanic ash events. As a response to the strong impact of the Eyjafjallajökull eruption in 2010, the UK Civil Aviation Authority (CAA) financed a lidar - sunphotometer network for NRT monitoring of the volcanic ash. This new network will consist of nine fixed sites and one mobile unit, each equipped with a lidar and a sunphotometer. The sunphotometers were acquired from Cimel Electronique (CE318-NE DPS9). The lidars were acquired from Raymetrics. They operate at 355 nm and have receiving channels at 355 nm (parallel and perpendicular polarization) and 387 nm (N2 Raman). The first two lidar systems were deployed in November 2014 at Camborne (SW England) and the data are under evaluation. The network is planned to be operational in 2016. Initially, the NRT data will consist of quick look plots of the total range corrected signal and volume depolarization ratio from lidar and aerosol optical depth from sunphotometer (including 355nm, through interpolation). During EGU presentation, the following features will be emphasized: IT considerations for the operational network, data quality assurance (including error estimates) for the

  11. Stuart London's standard of living: re-examining the Settlement of Tithes of 1638 for rents, income, and poverty.

    PubMed

    Baer, William C

    2010-01-01

    The Settlement of Tithes of 1638 can be tested for biases in its London rents. Even so, it proves to be a relatively good source for seventeenth-century London, and for calculating associated median and mean rents, as well as a Gini coefficient of inequality for the distribution of resources. Through other evidence in the Settlement, rent/income ratios for London can be approximated, and from them estimates made of London's median income. Median rents and income also allow estimates of the percentage of Londoners in poverty. Though the last is inevitably disputable, the estimate holds up well to testing by other evidence.

  12. Learning from UK primary care.

    PubMed

    Hays, Richard

    2009-03-01

    The Australian Government is wise to examine other health care systems as it strives to improve the quality of care and address rising costs to both governments and individuals. Focus is currently on the United Kingdom, whose National Health Service (NHS) stands out as one that delivers good care at a reasonable price to all who need it. The Australian and UK systems have many similarities: universal access, tax payer support, no or low cost at point of delivery, and good population health outcomes. They also face similar pressures on services from aging, increasingly unwell yet expectant populations.However, there are also differences, largely in the way that health care is funded, organised and delivered. The NHS is a huge system for 60 million people in four home countries with diverging policies. Within England, the system is managed through 10 strategic health authorities, each responsible for about 5 million people and having the right to interpret national policy. Population based health care, including tertiary care, is funded locally via primary care trusts.

  13. UK organisation of access care.

    PubMed

    Wilmink, Teun; Powers, Sarah; Baharani, Jyoti

    2015-01-01

    National UK audits show that 73% of patients start renal replacement therapy (RRT) with haemodialysis (HD). However, 59% of those start HD on non-permanent access in the form of a tunnelled line (TL) or a non-tunnelled line (NTL), 40% on an arteriovenous fistula (AVF) and 1% on an arteriovenous graft (AVG). After 3 months, the number of patients dialysing on AVF was only 41%. Late referrals, within 90 days of starting dialysis to the renal service, occur in one-fifth of all incident HD patients. Referral to a surgeon was an important determinant of mode of access at first dialysis. However, referral to a surgeon occurred in 67% of patients who were known to the nephrologist for over a year and in 46% of patients who were known to nephrology less than a year but more than 90 days. Best practice tariffs of the National Health Service (NHS) payment by results program have set a target of 75% of prevalent HD occurring via an AVF or AVG in 2011/2012, rising to 85% in 2013/2014. We suggest that this target is best achieved by increasing timely referral to a surgeon for creation of access before HD is needed.

  14. The London polonium incident: lessons in risk communications.

    PubMed

    Rubin, G James; Amlôt, Richard; Page, Lisa

    2011-11-01

    Public responses to large-scale radiological incidents are often thought to be disproportionate to the objective risk and can involve widespread societal disruption. Recent experiences of the (200)Po incident in central London suggest that public responses depend heavily on the nature of the incident and the effectiveness of risk communication efforts. This paper describes the outcome of several studies done in the aftermath of the (200)Po incident that suggest the reaction of the public on this occasion was muted, even for those directly affected. However, the desire for accurate, up-to-date and individually-tailored information was strong, and satisfaction with the efforts of the responding agencies was mediated by this information provision. A small minority of individuals was difficult to reassure effectively. This group may confer a particular drain on resources. Lessons for the risk communication efforts of public health responders are identified, in particular the importance of helping individuals to identify their risk of exposure, understand the difference between acute and chronic effects of exposure, and appreciate the meaning of any test results. Attempts at providing reassurance in the absence of specific information are likely to be counterproductive in any future radiological incident.

  15. Improved performance in the Tower of London test following yoga.

    PubMed

    Manjunath, N K; Telles, S

    2001-07-01

    Twenty girls between 10 and 13 years of age, studying at a residential school were randomly assigned to two groups. One group practiced yoga for one hour fifteen minutes per day, 7 days a week, while the other group was given physical training for the same time. Time for planning and for execution and the number of moves required to complete the Tower of London task were assessed for both groups at the beginning and end of a month. These three assessments were separately tested in increasingly complex tasks requiring 2-moves, 4-moves and 5-moves. The pre-post data were compared using the Wilcoxon paired signed ranks test. The yoga group showed a significant reduction in planning time for both 2-moves and 4-moves tasks (53.9 and 59.1 percent respectively), execution time in both 4-moves and 5-moves tasks (63.7 and 60.3 percent respectively), and in the number of moves in the 4-moves tasks (20.9 percent). The physical training group showed no change. Hence yoga training for a month reduced the planning and execution time in simple (2-moves) as well as complex tasks (4, 5-moves) and facilitated reaching the target with a smaller number of moves in a complex task (4-moves).

  16. Urban smoke concentrations at Kew, London, 1898-2004

    NASA Astrophysics Data System (ADS)

    Harrison, R. G.

    Historical smoke concentrations at monthly resolution for the early twentieth century are found for Kew Observatory, London, using the atmospheric electricity proxy technique. Smoke particles modify the electrical properties of urban air: an increase in smoke concentration reduces air's electrical conductivity and increases the Potential Gradient (PG). Calibrated PG data are available from Kew since 1898, and air conductivity was measured routinely between 1909 and 1979 using the technique developed by C.T.R. Wilson. Automated smoke observations at the same site overlap with the atmospheric electrical measurements from 1921, providing an absolute calibration to smoke concentration. This shows that the late nineteenth century winter smoke concentrations at Kew were approximately 100 times greater than contemporary winter smoke concentrations. Following smoke emission regulations reducing the smoke concentration, the electrical parameters of the urban air did not change dramatically. This is suggested to be due to a composition change, with an increase in the abundance of small aerosol compensating for the decrease in smoke.

  17. Persistent sulfate formation from London Fog to Chinese haze

    NASA Astrophysics Data System (ADS)

    Wang, Gehui; Zhang, Renyi; Gomez, Mario E.; Yang, Lingxiao; Levy Zamora, Misti; Hu, Min; Lin, Yun; Peng, Jianfei; Guo, Song; Meng, Jingjing; Li, Jianjun; Cheng, Chunlei; Hu, Tafeng; Ren, Yanqin; Wang, Yuesi; Gao, Jian; Cao, Junji; An, Zhisheng; Zhou, Weijian; Li, Guohui; Wang, Jiayuan; Tian, Pengfei; Marrero-Ortiz, Wilmarie; Secrest, Jeremiah; Du, Zhuofei; Zheng, Jing; Shang, Dongjie; Zeng, Limin; Shao, Min; Wang, Weigang; Huang, Yao; Wang, Yuan; Zhu, Yujiao; Li, Yixin; Hu, Jiaxi; Pan, Bowen; Cai, Li; Cheng, Yuting; Ji, Yuemeng; Zhang, Fang; Rosenfeld, Daniel; Liss, Peter S.; Duce, Robert A.; Kolb, Charles E.; Molina, Mario J.

    2016-11-01

    Sulfate aerosols exert profound impacts on human and ecosystem health, weather, and climate, but their formation mechanism remains uncertain. Atmospheric models consistently underpredict sulfate levels under diverse environmental conditions. From atmospheric measurements in two Chinese megacities and complementary laboratory experiments, we show that the aqueous oxidation of SO2 by NO2 is key to efficient sulfate formation but is only feasible under two atmospheric conditions: on fine aerosols with high relative humidity and NH3 neutralization or under cloud conditions. Under polluted environments, this SO2 oxidation process leads to large sulfate production rates and promotes formation of nitrate and organic matter on aqueous particles, exacerbating severe haze development. Effective haze mitigation is achievable by intervening in the sulfate formation process with enforced NH3 and NO2 control measures. In addition to explaining the polluted episodes currently occurring in China and during the 1952 London Fog, this sulfate production mechanism is widespread, and our results suggest a way to tackle this growing problem in China and much of the developing world.

  18. Fatty liver in birds at the Zoological Society of London.

    PubMed

    Wadsworth, P F; Jones, D M; Pugsley, S L

    1984-04-01

    The livers of 531 captive wild birds necropsied at the Zoological Society of London were examined histologically. Marked fatty infiltration of the liver was found in 13 cases. Seven of the 13 cases were from the order Psittaciformes indicating that some species (cockatoos, parakeets and parrots) in this order may be particularly susceptible to fatty infiltration of the liver. Affected livers were commonly swollen or enlarged, pale, white or yellow in colour and soft, friable or fatty at post mortem examination. Histologically, marked fatty infiltration of the liver was characterised by the presence of intracytoplasmic fat vacuoles within hepatocytes without zonal or lobular distribution throughout the sections examined. Reticulolysis and fibrosis of the hepatic parenchyma were found in association with marked fatty liver in a proportion of cases. Macroscopic or histological evidence of hepatic haemorrhages was not found in affected birds. In psittacine birds, obesity was frequently seen at post mortem examination and it was considered that nutritional and/or metabolic factors were important causes of fatty liver in this group. Fatty liver was found in association with chronic wasting diseases caused by mycotic infection in two cases.

  19. Persistent sulfate formation from London Fog to Chinese haze

    PubMed Central

    Wang, Gehui; Zhang, Renyi; Gomez, Mario E.; Yang, Lingxiao; Levy Zamora, Misti; Hu, Min; Lin, Yun; Peng, Jianfei; Guo, Song; Meng, Jingjing; Li, Jianjun; Cheng, Chunlei; Hu, Tafeng; Ren, Yanqin; Wang, Yuesi; Gao, Jian; Cao, Junji; An, Zhisheng; Zhou, Weijian; Li, Guohui; Wang, Jiayuan; Tian, Pengfei; Marrero-Ortiz, Wilmarie; Secrest, Jeremiah; Du, Zhuofei; Zheng, Jing; Shang, Dongjie; Zeng, Limin; Shao, Min; Wang, Weigang; Huang, Yao; Wang, Yuan; Zhu, Yujiao; Li, Yixin; Hu, Jiaxi; Pan, Bowen; Cai, Li; Cheng, Yuting; Ji, Yuemeng; Zhang, Fang; Rosenfeld, Daniel; Liss, Peter S.; Duce, Robert A.; Kolb, Charles E.; Molina, Mario J.

    2016-01-01

    Sulfate aerosols exert profound impacts on human and ecosystem health, weather, and climate, but their formation mechanism remains uncertain. Atmospheric models consistently underpredict sulfate levels under diverse environmental conditions. From atmospheric measurements in two Chinese megacities and complementary laboratory experiments, we show that the aqueous oxidation of SO2 by NO2 is key to efficient sulfate formation but is only feasible under two atmospheric conditions: on fine aerosols with high relative humidity and NH3 neutralization or under cloud conditions. Under polluted environments, this SO2 oxidation process leads to large sulfate production rates and promotes formation of nitrate and organic matter on aqueous particles, exacerbating severe haze development. Effective haze mitigation is achievable by intervening in the sulfate formation process with enforced NH3 and NO2 control measures. In addition to explaining the polluted episodes currently occurring in China and during the 1952 London Fog, this sulfate production mechanism is widespread, and our results suggest a way to tackle this growing problem in China and much of the developing world. PMID:27849598

  20. INVITATION : Latest astronomical results from ISO: Press briefing in London

    NASA Astrophysics Data System (ADS)

    1998-03-01

    Representatives of the media are invited to attend the briefing at the Institute of Physics, which will commence with registration and demonstrations at 10:00 a.m. London time. As of 10:30, Paul Murdin, Head of Astronomy at PPARC will initiate the briefing on behalf of PPARC. Reinhard Genzel, a German astronomer and Director of the Max Planck Institute, will make an independent assessment of ISO's achievements and announce some recent discoveries. Martin Kessler, the European Space Agency's project scientist, will summarize the extent of ISO's observations and describe the continuing work of analysis. At 11:45 (after questions) ISO scientists will be available for interviews, with quiet rooms for radio interviews and a scale model of ISO as backdrop for TV interviews and still pictures. Other facilities will include digital images from ISO, and a demonstration of educational project work. To coincide with the event, ESA will distribute a video news release, an Information Note, and new pictures from ISO. After the briefing there will be a buffet lunch. The nearest underground stations to the Institute of Physics are Great Portland Street and Regent's Park. Representatives of the media wishing to attend are requested to return by fax (+33(0)1.53.69.76.90) the attached accreditation form. For further information, please contact : ESA Public Relations Division Tel : +33(0)1.53.69.71.55 Fax : +33(0)1.53.69.76.90

  1. Ethnic variations in orthodontic treatment need in London schoolchildren

    PubMed Central

    Alkhatib, Mhd Nour; Bedi, Raman; Foster, Claire; Jopanputra, Pooja; Allan, Sue

    2005-01-01

    Background The study was carried out to determine the prevalence of orthodontic treatment need in children from minority ethnic groups and compare the need to the white population. The second objective was to explore variations in agreement between subjective and objective treatment need in a multiethnic context using the aesthetic component of Orthodontic Treatment Need Index (IOTN AC). Methods A cross-sectional study in North West London, 14 schools were randomly selected from the 27 schools in the two boroughs of Harrow and Hillingdon. Comparison between objective and subjective treatment need was carried out using IOTN AC index. Clinical orthodontic treatment need was also recorded using the dental health component of Orthodontic Treatment Need Index (IOTN DHC). Results 2,788 children were examined and completed the questionnaire. 16% of the study population were already wearing appliances or had finished orthodontic treatment. Of the remaining children; 15% had definite need for treatment using the dental health component of the IOTN. There was no significant variation in the need for orthodontic treatment between different ethnic backgrounds (P > 0.05) whether using the AC or DHC components of the IOTN index. However, poor agreement was detected between professional and subjective assessment of ethnic minority of orthodontic treatment need using IOTN AC index. Conclusion Orthodontic treatment need in children of ethnic minorities does not differ significantly from the vast majority of white children. However treatment need based on aesthetic index continues to vary in all ethnic groups from the professional aesthetic assessment PMID:16188024

  2. Governing UK medical performance: a struggle for policy dominance.

    PubMed

    Salter, Brian

    2007-08-01

    In the UK, policy on the governance of medical performance is characterised by a continuing struggle between state and profession for control of the agenda setting, formation and implementation stages of the policy process. Since 1998 both sides have continued to produce policies in response to highly visible political pressures but have yet to agree on how those policies should engage as they are implemented at the level of the individual practitioner. For the state, clinical governance forms the lynchpin of its drive to increase managerial control over doctors and, for the profession, revalidation is seen as the means for ensuring the quality of medical performance whilst preserving medicine's historic autonomy. This paper analyses the course of this 7-year struggle and shows how in constructing and delivering policy, state and profession draw on quite different and separate sets of institutional structures and values. As a consequence, there is an unresolved competition for dominance and little engagement between the two policy streams.

  3. Demographics, management and health of donkeys in the UK.

    PubMed

    Cox, R; Burden, F; Proudman, C J; Trawford, A F; Pinchbeck, G L

    2010-05-01

    In this paper, the management and health problems of donkeys on loan to independent carers from The Donkey Sanctuary are characterised, and the demographics of the UK's donkey population are described using data from a variety of sources. All carers that fostered a donkey from The Donkey Sanctuary between September 2004 and August 2005 (1432 donkeys) were surveyed using a postal questionnaire requesting information about the donkey, its premises, daily care, health and preventive medicine. The response rate was 77.8 percent. The mean (sd) age of the donkeys was 20.8 (7.4) years. The majority (92 percent) of the donkeys were kept as pets. Approximately one-third (33.6 percent) of the donkeys were overweight. The most common medical problems were hoof, dermal and oral problems. A total of 86 percent of the donkeys had a dental examination at least every 12 months, and at least 45 percent had at least one dental problem.

  4. Community organizing and community health: piloting an innovative approach to community engagement applied to an early intervention project in south London

    PubMed Central

    Bolton, Matthew; Moore, Imogen; Ferreira, Ana; Day, Crispin; Bolton, Derek

    2016-01-01

    Background The importance of community engagement in health is widely recognized, and key themes in UK National Institute for Health and Clinical Excellence (NICE) recommendations for enhancing community engagement are co-production and community control. This study reports an innovative approach to community engagement using the community-organizing methodology, applied in an intervention of social support to increase social capital, reduce stress and improve well-being in mothers who were pregnant and/or with infants aged 0–2 years. Methods Professional community organizers in Citizens-UK worked with local member civic institutions in south London to facilitate social support to a group of 15 new mothers. Acceptability of the programme, adherence to principles of co-production and community control, and changes in the outcomes of interest were assessed quantitatively in a quasi-experimental design. Results The programme was found to be feasible and acceptable to participating mothers, and perceived by them to involve co-production and community control. There were no detected changes in subjective well-being, but there were important reductions in distress on a standard self-report measure (GHQ-12). There were increases in social capital of a circumscribed kind associated with the project. Conclusions Community organizing provides a promising model and method of facilitating community engagement in health. PMID:25724610

  5. The development of forensic medicine in the United Kingdom from the 18th century.

    PubMed

    Eckert, W

    1992-06-01

    Forensic medicine in the United Kingdom includes both forensic pathology and clinical forensic medicine on the living. It began at the end of the 18th century, long after its development in Germany, Italy, France, and other countries in Europe. Initial beginnings were in Scotland, where a program began at the University of Edinburgh with the establishment of a chair in Forensic Medicine by Prof. Andrew Duncan Sr. The development in England began in London's Kings College Medical School with a chair held by Prof. William A. Guy. Later chairs in Forensic Medicine were established in Glasgow, Aberdeen, and in London, where Forensic Medicine was taught at St. Mary's Hospital Medical School, Guy's Hospital Medical School, London Hospital Medical School, Charing Cross Hospital Medical School, St. Thomas Hospital Medical School, and St. George's Hospital Medical School. In other cities in England, Wales, and Northern Ireland, departments were founded in Leeds, Manchester, Cardiff, and Belfast. Many textbooks were prepared during this time by professors from these medical schools and by others working in nonacademic areas. The development of coroner activities and those of the police surgeons is also part of the study of forensic medicine.

  6. UK Announces Intention to Join ESO

    NASA Astrophysics Data System (ADS)

    2000-11-01

    Summary The Particle Physics and Astronomy Research Council (PPARC) , the UK's strategic science investment agency, today announced that the government of the United Kingdom is making funds available that provide a baseline for this country to join the European Southern Observatory (ESO) . The ESO Director General, Dr. Catherine Cesarsky , and the ESO Community warmly welcome this move towards fuller integration in European astronomy. "With the UK as a potential member country of ESO, our joint opportunities for front-line research and technology will grow significantly", she said. "This announcement is a clear sign of confidence in ESO's abilities, most recently demonstrated with the construction and operation of the unique Very Large Telescope (VLT) on Paranal. Together we will look forward with confidence towards new, exciting projects in ground-based astronomy." It was decided earlier this year to place the 4-m UK Visible and Infrared Survey Telescope (VISTA) at Paranal, cf. ESO Press Release 03/00. Following negotiations between ESO and PPARC, a detailed proposal for the associated UK/ESO Agreement with the various entry modalities will now be presented to the ESO Council for approval. Before this Agreement can enter into force, the ESO Convention and associated protocols must also be ratified by the UK Parliament. Research and key technologies According to the PPARC press release, increased funding for science, announced by the UK government today, will enable UK astronomers to prepare for the next generation of telescopes and expand their current telescope portfolio through membership of the European Southern Observatory (ESO). The uplift to its baseline budget will enable PPARC to enter into final negotiations for UK membership of the ESO. This will ensure that UK astronomers, together with their colleagues in the ESO member states, are actively involved in global scale preparations for the next generation of astronomy facilities. among these are ALMA

  7. Wilderness medicine

    PubMed Central

    Sward, Douglas G.; Bennett, Brad L.

    2014-01-01

    BACKGROUND: Human activity in wilderness areas has increased globally in recent decades, leading to increased risk of injury and illness. Wilderness medicine has developed in response to both need and interest. METHODS: The field of wilderness medicine encompasses many areas of interest. Some focus on special circumstances (such as avalanches) while others have a broader scope (such as trauma care). Several core areas of key interest within wilderness medicine are discussed in this study. RESULTS: Wilderness medicine is characterized by remote and improvised care of patients with routine or exotic illnesses or trauma, limited resources and manpower, and delayed evacuation to definitive care. Wilderness medicine is developing rapidly and draws from the breadth of medical and surgical subspecialties as well as the technical fields of mountaineering, climbing, and diving. Research, epidemiology, and evidence-based guidelines are evolving. A hallmark of this field is injury prevention and risk mitigation. The range of topics encompasses high-altitude cerebral edema, decompression sickness, snake envenomation, lightning injury, extremity trauma, and gastroenteritis. Several professional societies, academic fellowships, and training organizations offer education and resources for laypeople and health care professionals. CONCLUSIONS: The future of wilderness medicine is unfolding on multiple fronts: education, research, training, technology, communications, and environment. Although wilderness medicine research is technically difficult to perform, it is essential to deepening our understanding of the contribution of specific techniques in achieving improvements in clinical outcomes. PMID:25215140

  8. Medical Practice, Urban Politics and Patronage: The London ‘Commonalty’ of Physicians and Surgeons of the 1420s *

    PubMed Central

    Ralley, Robert

    2015-01-01

    Medical practice in fifteenth-century England is often seen as suffering from the low status and unregulated practice of which Thomas Linacre later complained. Unlike in many European cities, the provision of physic was uncontrolled, and while urban guilds oversaw surgery as a manual art, no comprehensive system of medical organisation or regulation existed. However, in a remarkable episode of the 1420s, a group of university-trained physicians and elite surgeons associated with Humphrey, Duke of Gloucester, briefly established just such a system. While their efforts initially secured approval for a national scheme, it was only in the City of London that they succeeded in implementing their plans. The detailed ordinances of the collegiate ‘commonalty’ they founded provide a unique insight into their attitudes. Drawing on continental models, they attempted to control all medicine within the city by establishing a hierarchy of practitioners, preventing illicit and incompetent practice, and offering treatment to even the poorest Londoners. Yet they failed to appreciate the vested interests of civic politics: achieving these aims meant curtailing the rights of the powerful Grocers and the Barbers, a fact made clear by their adjudication of a case involving two members of the Barbers’ Company, and the Barbers’ subsequent riposte—a mayoral petition that heralded the commonalty’s end. Its founder surgeons went on to revitalise their Surgeons’ Fellowship, which continued independently of the Barbers until a merger in 1540; in contrast, the physicians withdrew from civic affairs, and physic remained entirely unregulated until episcopal licensing was instituted in 1511. PMID:27019518

  9. Vocational Qualifications for the UK Explosives Industry

    DTIC Science & Technology

    2010-07-15

    possible consequences of a lack of competence when working with munitions or explosives can be devastating and the UK has long held concerns over these...their workforces; • activities with significant, or indeed, perceived health and safety and public safety risks are subject to increasingly...www.homelandsecurityqualifications.co.uk 4 National Occupational Standards (NOS) for Explosives Substances and Articles (ESA). The Health and Safety Executive (HSE) has

  10. Scoping the role and education needs of practice nurses in London.

    PubMed

    Procter, Susan; Griffiths, Lauren; Fanning, Agnes; Wallman, Lizzie; Loveday, Heather P

    2017-03-27

    Aims To identify education priorities for practice nursing across eight London Clinical Commissioning Groups (CCGs); to identify the education, training, development and support needs of practice nurses in undertaking current and future roles.

  11. Tracer concentration profiles measured in central London as part of the REPARTEE campaign

    NASA Astrophysics Data System (ADS)

    Martin, D.; Petersson, K. F.; White, I. R.; Henshaw, S. J.; Nickless, G.; Lovelock, A.; Barlow, J. F.; Dunbar, T.; Wood, C. R.; Shallcross, D. E.

    2011-01-01

    There have been relatively few tracer experiments carried out that have looked at vertical plume spread in urban areas. In this paper we present results from two tracer (cyclic perfluorocarbon) experiments carried out in 2006 and 2007 in central London centred on the BT Tower as part of the REPARTEE (Regent's Park and Tower Environmental Experiment) campaign. The height of the tower gives a unique opportunity to study vertical dispersion profiles and transport times in central London. Vertical gradients are contrasted with the relevant Pasquill stability classes. Estimation of lateral advection and vertical mixing times are made and compared with previous measurements. Data are then compared with a simple operational dispersion model and contrasted with data taken in central London as part of the DAPPLE campaign. This correlates dosage with non-dimensionalised distance from source. Such analyses illustrate the feasibility of the use of these empirical correlations over these prescribed distances in central London.

  12. Outcomes of domestic violence screening at an acute London trust: are there missed opportunities for intervention?

    PubMed Central

    Warren-Gash, Charlotte; Bartley, Angela; Bayly, Jude; Dutey-Magni, Peter; Edwards, Sarah; Madge, Sara; Miller, Charlotte; Nicholas, Rachel; Radhakrishnan, Sheila; Sathia, Leena; Swarbrick, Helen; Blaikie, Dee; Rodger, Alison

    2016-01-01

    Objectives Domestic violence screening is advocated in some healthcare settings. Evidence that it increases referral to support agencies or improves health outcomes is limited. This study aimed to (1) investigate the proportion of hospital patients reporting domestic violence, (2) describe characteristics and previous hospital attendances of affected patients and (3) assess referrals to an in-house domestic violence advisor from Camden Safety Net. Design A series of observational studies. Setting Three outpatient clinics at the Royal Free London NHS Foundation Trust. Participants 10 158 patients screened for domestic violence in community gynaecology, genitourinary medicine (GUM) and HIV medicine clinics between 1 October 2013 and 30 June 2014. Also 2253 Camden Safety Net referrals over the same period. Main outcome measures (1) Percentage reporting domestic violence by age group gender, ethnicity and clinic. (2) Rates of hospital attendances in the past 3 years for those screening positive and negative. (3) Characteristics, uptake and risk assessment results for hospital in-house domestic violence referrals compared with Camden Safety Net referrals from other sources. Results Of the 10 158 patients screened, 57.4% were female with a median age of 30 years. Overall, 7.1% reported ever-experiencing domestic violence, ranging from 5.7% in GUM to 29.4% in HIV services. People screening positive for domestic violence had higher rates of previous emergency department attendances (rate ratio (RR) 1.63, 95% CI 1.09 to 2.48), emergency inpatient admissions (RR 2.27, 95% CI 1.37 to 3.84) and day-case admissions (RR 2.03, 95% CI 1.23 to 3.43) than those screening negative. The 77 hospital referrals to the hospital-based domestic violence advisor during the study period were more likely to be taken up and to be classified as high risk than referrals from elsewhere. Conclusions Selective screening for domestic violence in high-risk hospital clinic populations has the

  13. Medicines management.

    PubMed

    Pegram, Anne; Bloomfield, Jacqueline

    2015-04-15

    All newly registered graduate nurses are required to have the appropriate knowledge and understanding to perform the skills required for patient care, specifically the competencies identified in the Nursing and Midwifery Council's essential skills clusters. This article focuses on the fifth essential skills cluster – medicines management. Nursing students should work to attain the knowledge and skills required for effective medicines management throughout their pre-registration education. The roles and responsibilities of the newly registered graduate nurse in the area of medicines management are discussed in this the final article of the essential skills cluster series.

  14. Precision Medicine

    PubMed Central

    Cholerton, Brenna; Larson, Eric B.; Quinn, Joseph F.; Zabetian, Cyrus P.; Mata, Ignacio F.; Keene, C. Dirk; Flanagan, Margaret; Crane, Paul K.; Grabowski, Thomas J.; Montine, Kathleen S.; Montine, Thomas J.

    2017-01-01

    Three key elements to precision medicine are stratification by risk, detection of pathophysiological processes as early as possible (even before clinical presentation), and alignment of mechanism of action of intervention(s) with an individual's molecular driver(s) of disease. Used for decades in the management of some rare diseases and now gaining broad currency in cancer care, a precision medicine approach is beginning to be adapted to cognitive impairment and dementia. This review focuses on the application of precision medicine to address the clinical and biological complexity of two common neurodegenerative causes of dementia: Alzheimer disease and Parkinson disease. PMID:26724389

  15. Aspects of higher training in emergency medicine

    PubMed Central

    Kilroy, D

    2003-01-01

    Objectives: To devise and develop a structured questionnaire addressing important issues relating to specialist registrar training in emergency medicine in the UK, and to then administer this questionnaire nationally to higher trainees in order to establish current practice and opinion regarding those issues. Methods: Informal interviews with current trainees were undertaken to identify themes which might be of wider importance in relation to training. The transcriptions were incorporated into a discussion questionnaire which was circulated to other trainees and to members of the Joint Committee on Higher Training in Accident and Emergency. A postal survey was developed from this draft and distributed to all trainees currently registered with the Faculty of Accident and Emergency Medicine. Results: The response rate was 75%. Collective responses to certain aspects of training are demonstrated in order to reflect current practice and opinion among UK specialist registrars and to allow further debate. Conclusion: Development of a structured questionnaire allows issues in relation to training in emergency medicine to be assessed. The findings of the survey allow national data to be presented which will be of interest to trainees and trainers in the UK as well as overseas. PMID:12954958

  16. Life cycle assessment of energy from waste via anaerobic digestion: a UK case study.

    PubMed

    Evangelisti, Sara; Lettieri, Paola; Borello, Domenico; Clift, Roland

    2014-01-01

    Particularly in the UK, there is potential for use of large-scale anaerobic digestion (AD) plants to treat food waste, possibly along with other organic wastes, to produce biogas. This paper presents the results of a life cycle assessment to compare the environmental impacts of AD with energy and organic fertiliser production against two alternative approaches: incineration with energy production by CHP and landfill with electricity production. In particular the paper investigates the dependency of the results on some specific assumptions and key process parameters. The input Life Cycle Inventory data are specific to the Greater London area, UK. Anaerobic digestion emerges as the best treatment option in terms of total CO2 and total SO2 saved, when energy and organic fertiliser substitute non-renewable electricity, heat and inorganic fertiliser. For photochemical ozone and nutrient enrichment potentials, AD is the second option while incineration is shown to be the most environmentally friendly solution. The robustness of the model is investigated with a sensitivity analysis. The most critical assumption concerns the quantity and quality of the energy substituted by the biogas production. Two key issues affect the development and deployment of future anaerobic digestion plants: maximising the electricity produced by the CHP unit fuelled by biogas and to defining the future energy scenario in which the plant will be embedded.

  17. UK energy minister sees strong E and P as key to healthy economy

    SciTech Connect

    1997-11-01

    A watershed event occurred on May 1, 1997, when Britain`s Labour Party achieved its greatest electoral victory of the 20th century by winning an incredible 419 seats in parliament. Prior to the election, there had been some nervousness among companies in the UK`s E and P sector about the prospect of a Labour administration. After 18 years of Conservative rule, the industry had grown comfortable with the status quo and feared that a switch of parties might bring unwelcome changes to oil and gas policy. That has not occurred, so far, during the first six months of Labour`s reign. Prime Minister Tony Blair has entrusted energy matters to Mr. John Battle, MP, the new Minister of Science, Energy and Industry within the Department of Trade and Industry. As the son of a nuclear engineer, the 46-year-old minister has a unique appreciation of the benefits that industry, technology and science bring to everyday people`s lives. During a recent, multi-country fact-finding tour, World Oil International Editor Kurt Abraham sat down with Minister Battle at his DTI office in London to discuss the state of Britain`s upstream, as seen through the eyes of the new regime.

  18. Subgroup differences in psychosocial factors relating to coronary heart disease in the UK South Asian population☆

    PubMed Central

    Williams, Emily D.; Nazroo, James Y.; Kooner, Jaspal S.; Steptoe, Andrew

    2010-01-01

    Objectives To explore the differences in psychosocial risk factors related to coronary heart disease (CHD) between South Asian subgroups in the UK. South Asian people suffer significantly higher rates of CHD than other ethnic groups, but vulnerability varies between South Asian subgroups, in terms of both CHD rates and risk profiles. Psychosocial factors may contribute to the excess CHD propensity that is observed; however, subgroup heterogeneity in psychosocial disadvantage has not previously been systematically explored. Methods With a cross-sectional design, 1065 healthy South Asian and 818 white men and women from West London, UK, completed psychosocial questionnaires. Psychosocial profiles were compared between South Asian religious groups and the white sample, using analyses of covariance and post hoc tests. Results Of the South Asian sample, 50.5% was Sikh, 28.0% was Hindu, and 15.8% was Muslim. Muslim participants were more socioeconomically deprived and experienced higher levels of chronic stress, including financial strain, low social cohesion, and racial discrimination, compared with other South Asian religious groups. In terms of health behaviors, Muslim men smoked more than Sikhs and Hindus, and Muslims also reported lower alcohol consumption and were less physically active than other groups. Conclusion This study found that Muslims were exposed to more psychosocial and behavioral adversity than Sikhs and Hindus, and highlights the importance of investigating subgroup heterogeneity in South Asian CHD risk. PMID:20846539

  19. High rate of lymphoma among a UK cohort of adolescents with vertically acquired HIV-1 infection transitioning to adult care in the era of antiretroviral therapy.

    PubMed

    Eades, Chris P; Herbert, Sophie A; Edwards, Simon G; Waters, Laura J; Peake, Tabitha; Miller, Robert F; Jungmann, Eva

    2016-01-02

    Among an inner London UK cohort of 147 adolescents transitioning from paediatric into adult care between 2007 and 2015, a new diagnosis of lymphoma was made in five patients; incidence rate = 0.425/100 person-years (95% confidence interval = 0.424-0.426). Previously described risk factors, including low nadir CD4 cell count and ongoing HIV-1 viraemia, appeared to be important. These data suggest that careful surveillance and a low threshold for investigating relevant symptoms continue to be essential for such patients.

  20. Nuclear Medicine

    MedlinePlus

    ... here Home » Science Education » Science Topics » Nuclear Medicine SCIENCE EDUCATION SCIENCE EDUCATION Science Topics Resource Links for ... administered by inhalation, by oral ingestion, or by direct injection into an organ. The mode of tracer ...

  1. The impact of market oriented reforms on choice and information: a case study of cataract surgery in outer London and Stockholm.

    PubMed

    Fotaki, M

    1999-05-01

    In the early 1990s, a set of market-oriented reforms was introduced into health care systems of the UK and Sweden, two exemplary cases of reliance on planned budgeting and integrated provision of services. In the pursuit of increased efficiency, several County Councils in Sweden have followed the public competition model, while in the UK internal market reforms were introduced. It was expected that the separation of functions of planners and purchasers from those of providers, which were to be freely chosen by the former, would achieve higher allocative efficiency but also enhance users' satisfaction with care. This paper uses cataract surgery as a case study to trace the impact of competition among providers on choice and information. Qualitative research methods were employed to record the perception of changes in their type and amount as it was given to both purchasers and patients. A set of open ended and standardised questionnaires was designed to elicit the views of all actors involved and to measure the likely transformations. Four study sites from Outer London were selected representing the diversity of responses, and the only existing large provider of eye services to Stockholm County Council was used. The analysis of the data showed that the quasi-market reforms have resulted in a change of attitude of providers. Some improvements in the amount and type of information given to purchasers and patients could also be detected, although as far as direct users were concerned, the demand has not been fully satisfied. However, the impact on choice available to patients and purchasers alike seemed to be adverse, an effect that was particularly strong in the UK case.

  2. Down and Out in London: Addictive Behaviors in Homelessness

    PubMed Central

    Sharman, Steve; Dreyer, Jenny; Clark, Luke; Bowden-Jones, Henrietta

    2016-01-01

    Backgrounds and aims Problem gambling occurs at higher levels in the homeless than the general population. Past work has not established the extent to which problem gambling is a cause or consequence of homelessness. This study sought to replicate recent observations of elevated rates of problem gambling in a British homeless sample, and extend that finding by characterizing (a) the temporal sequencing of the effect, (b) relationships with drug and alcohol misuse, and (c) awareness and access of treatment services for gambling by the homeless. Methods We recruited 72 participants from homeless centers in Westminster, London, and used the Problem Gambling Severity Index to assess gambling involvement, as well as DSM-IV criteria for substance and alcohol use disorders. A life-events scale was administered to establish the temporal ordering of problem gambling and homelessness. Results Problem gambling was evident in 23.6% of the sample. In participants who endorsed any gambling symptomatology, the majority were categorized as problem gamblers. Within those problem gamblers, 82.4% indicated that gambling preceded their homelessness. Participants displayed high rates of substance (31.9%) and alcohol dependence (23.6%); these were not correlated with PGSI scores. Awareness of treatment for gambling was significantly lower than for substance and alcohol use disorders, and actual access of gambling support was minimal. Discussion and conclusions Problem gambling is an under-recognized health issue in the homeless. Our observation that gambling typically precedes homelessness strengthens its role as a causal factor. Despite the elevated prevalence rates, awareness and utilization of gambling support opportunities were low compared with services for substance use disorders. PMID:27348556

  3. Down and Out in London: Addictive Behaviors in Homelessness.

    PubMed

    Sharman, Steve; Dreyer, Jenny; Clark, Luke; Bowden-Jones, Henrietta

    2016-06-01

    Backgrounds and aims Problem gambling occurs at higher levels in the homeless than the general population. Past work has not established the extent to which problem gambling is a cause or consequence of homelessness. This study sought to replicate recent observations of elevated rates of problem gambling in a British homeless sample, and extend that finding by characterizing (a) the temporal sequencing of the effect, (b) relationships with drug and alcohol misuse, and (c) awareness and access of treatment services for gambling by the homeless. Methods We recruited 72 participants from homeless centers in Westminster, London, and used the Problem Gambling Severity Index to assess gambling involvement, as well as DSM-IV criteria for substance and alcohol use disorders. A life-events scale was administered to establish the temporal ordering of problem gambling and homelessness. Results Problem gambling was evident in 23.6% of the sample. In participants who endorsed any gambling symptomatology, the majority were categorized as problem gamblers. Within those problem gamblers, 82.4% indicated that gambling preceded their homelessness. Participants displayed high rates of substance (31.9%) and alcohol dependence (23.6%); these were not correlated with PGSI scores. Awareness of treatment for gambling was significantly lower than for substance and alcohol use disorders, and actual access of gambling support was minimal. Discussion and conclusions Problem gambling is an under-recognized health issue in the homeless. Our observation that gambling typically precedes homelessness strengthens its role as a causal factor. Despite the elevated prevalence rates, awareness and utilization of gambling support opportunities were low compared with services for substance use disorders.

  4. Work characteristics and psychiatric disorder in civil servants in London.

    PubMed Central

    Stansfeld, S A; North, F M; White, I; Marmot, M G

    1995-01-01

    STUDY OBJECTIVE--To describe the association between self reported and externally assessed work characteristics and psychiatric disorder. DESIGN--Analysis of questionnaire data collected from the first phase of the Whitehall II study, a cohort study of an employed population. SETTING--Twenty civil service departments in London. PARTICIPANTS--Altogether 6900 male and 3414 female civil servants aged 35-55 years. MAIN RESULTS--High levels of subjective social support at work, control at work, job variety, and skill use were associated with greater satisfaction and wellbeing and less psychiatric disorder measured by the 30 item general health questionnaire (GHQ). High levels of subjective work pace and conflicting demands were associated with less satisfaction and wellbeing and greater psychiatric disorder. The combined effects of work characteristics were similar to the effects of the work characteristics considered separately, except that for men there was a small interaction between psychological demands and control on the GHQ. There was little overall support for the two factor job strain model. In contrast, objective indices of work were generally not associated with the psychological indices. Findings in men and women were generally comparable and were not significantly influenced by employment grade. CONCLUSIONS--Negative affectivity and a tendency to report negatively about both work and the psychological indices may partly explain the difference in the findings between subjective and objective work characteristics. However, subjective work characteristics were still associated with psychiatric disorder after adjusting for negative affectivity. The potential confounding effects of employment grade did not explain the association between either subjective or objective work characteristics and the psychological indices. While modifications to the work environment may directly reduce certain adverse physical health effects, the influence of work place design and

  5. Millennium-long damage to building materials in London.

    PubMed

    Brimblecombe, Peter; Grossi, Carlota M

    2009-02-01

    Damage functions from a range of sources are used to estimate deterioration of carbonate stone, iron and copper, in addition to the rate of blackening of stone surfaces in London across the period 1100-2100 CE. Meteorological and pollution input is available for only a relatively short part of this span, so non-instrumental weather records and modelled pollution are utilised for historic values, while future climate is adapted from the HadCM3A2 model output and pollution assessed from likely regulatory trends. The results from the different damage functions compare reasonably well showing comparable changes in damage rates with time. A potential square-root dependence of change in deposition velocity of SO2 to limestone suggests a possible overestimate of damage when pollution is high. Deterioration is especially intense from the 1700s. It is difficult to be certain whether the corrosion of copper accelerated as early as this or it developed in the 20th century. Nevertheless all the functions predict a decline in copper corrosion from the end of the 20th century. A blackening function was developed to relate elemental carbon concentration and the colour of deposited particulate matter to blackening rate, which suggests that soiling was particularly rapid in the late 19th century. The increase and subsequent decrease in damage to building materials is interpreted in terms of a Kuznets curve. The centuries where pollution controlled damage to durable building material seems to be over. Weathering, in a changing climate may have the greatest impact in the future.

  6. Military perspective on the civilian response to the London bombings July 2005.

    PubMed

    Bland, S A; Lockey, D J; Davies, G E; Kehoe, A D

    2006-03-01

    With the break up of the Warsaw Pact and changing global relations, current military deployments are becoming smaller and more expeditionary (e.g. Afghanistan, East Timor and Sierra Leone). During the Cold War, the use of weapons of mass effect was highly likely to have been seen on the battlefield. Ironically, the proliferation of CBRN agents and the knowledge of their application, as well as the manufacture of improvised explosive devices, have lead to the targeting of civilian populations by extremist groups. One of the benefits of military clinicians embedded in NHS hospital trusts, as well as a strong reservist cadre, is a greater understanding of the implications and management of asymmetric attacks against the U.K. The experience and skills of military clinicians may be of benefit to NHS trusts while this type of threat exists. Military clinicians are also likely to benefit from the experience that they get in certain NHS posts that provide skills that are readily transferable to military medicine. The events of 7th July highlighted the dynamic use of deployable medical resources and a rapid return to normal service provision. This type of 'Health Resilience' can only be achieved with a combination of effective emergency planning, on scene clinical risk management and clinical leadership.

  7. Children's (Pediatric) Nuclear Medicine

    MedlinePlus Videos and Cool Tools

    ... Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small amounts ... Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  8. UK malaria treatment guidelines 2016.

    PubMed

    Lalloo, David G; Shingadia, Delane; Bell, David J; Beeching, Nicholas J; Whitty, Christopher J M; Chiodini, Peter L

    2016-06-01

    1.Malaria is the tropical disease most commonly imported into the UK, with 1300-1800 cases reported each year, and 2-11 deaths. 2. Approximately three quarters of reported malaria cases in the UK are caused by Plasmodium falciparum, which is capable of invading a high proportion of red blood cells and rapidly leading to severe or life-threatening multi-organ disease. 3. Most non-falciparum malaria cases are caused by Plasmodium vivax; a few cases are caused by the other species of plasmodium: Plasmodium ovale, Plasmodium malariae or Plasmodium knowlesi. 4. Mixed infections with more than one species of parasite can occur; they commonly involve P. falciparum with the attendant risks of severe malaria. 5. There are no typical clinical features of malaria; even fever is not invariably present. Malaria in children (and sometimes in adults) may present with misleading symptoms such as gastrointestinal features, sore throat or lower respiratory complaints. 6. A diagnosis of malaria must always be sought in a feverish or sick child or adult who has visited malaria-endemic areas. Specific country information on malaria can be found at http://travelhealthpro.org.uk/. P. falciparum infection rarely presents more than six months after exposure but presentation of other species can occur more than a year after exposure. 7. Management of malaria depends on awareness of the diagnosis and on performing the correct diagnostic tests: the diagnosis cannot be excluded until more than one blood specimen has been examined. Other travel related infections, especially viral haemorrhagic fevers, should also be considered. 8. The optimum diagnostic procedure is examination of thick and thin blood films by an expert to detect and speciate the malarial parasites. P. falciparum and P. vivax (depending upon the product) malaria can be diagnosed almost as accurately using rapid diagnostic tests (RDTs) which detect plasmodial antigens. RDTs for other Plasmodium species are not as reliable. 9

  9. The Academic Backbone: longitudinal continuities in educational achievement from secondary school and medical school to MRCP(UK) and the specialist register in UK medical students and doctors

    PubMed Central

    2013-01-01

    Background Selection of medical students in the UK is still largely based on prior academic achievement, although doubts have been expressed as to whether performance in earlier life is predictive of outcomes later in medical school or post-graduate education. This study analyses data from five longitudinal studies of UK medical students and doctors from the early 1970s until the early 2000s. Two of the studies used the AH5, a group test of general intelligence (that is, intellectual aptitude). Sex and ethnic differences were also analyzed in light of the changing demographics of medical students over the past decades. Methods Data from five cohort studies were available: the Westminster Study (began clinical studies from 1975 to 1982), the 1980, 1985, and 1990 cohort studies (entered medical school in 1981, 1986, and 1991), and the University College London Medical School (UCLMS) Cohort Study (entered clinical studies in 2005 and 2006). Different studies had different outcome measures, but most had performance on basic medical sciences and clinical examinations at medical school, performance in Membership of the Royal Colleges of Physicians (MRCP(UK)) examinations, and being on the General Medical Council Specialist Register. Results Correlation matrices and path analyses are presented. There were robust correlations across different years at medical school, and medical school performance also predicted MRCP(UK) performance and being on the GMC Specialist Register. A-levels correlated somewhat less with undergraduate and post-graduate performance, but there was restriction of range in entrants. General Certificate of Secondary Education (GCSE)/O-level results also predicted undergraduate and post-graduate outcomes, but less so than did A-level results, but there may be incremental validity for clinical and post-graduate performance. The AH5 had some significant correlations with outcome, but they were inconsistent. Sex and ethnicity also had predictive effects on

  10. Reisebericht London: Interner Workshop: "Knowledge Based Systems in Information Science" (London Travel Report: Internal Workshop: "Knowledge Based Systems in Information Science").

    ERIC Educational Resources Information Center

    Simon, Hans-Reiner

    Written in German, this report summarizes a workshop on teaching and research activities in information science that was held at the City University, London, and attended by faculty and students from the university's Department of Information Science and H.-R. Simon of the GID (Gesellschaft fur Information und Dokumentation), Frankfort am Main,…

  11. Entrepreneurship Education and Veterinary Medicine: Enhancing Employable Skills

    ERIC Educational Resources Information Center

    Henry, Colette; Treanor, Lorna

    2010-01-01

    Purpose: This paper has the purpose of exploring the potential for entrepreneurship education within veterinary medicine. It aims to examine some of the key themes in the entrepreneurship education literature, discuss the make-up of the UK veterinary sector, consider veterinary curricula requirements and illustrate how entrepreneurship education…

  12. Undergraduate Teaching in Geriatric Medicine: The Role of National Curricula

    ERIC Educational Resources Information Center

    Blundell, Adrian; Gordon, Adam; Gladman, John; Masud, Tahir

    2009-01-01

    There has been recent international concern that the teaching of geriatrics may be in decline. Research has suggested that support for geriatrics in national undergraduate curricula is the key to effective delivery of teaching in the specialty. We set out to determine the geriatric medicine content in the U.K. generic curriculum, reviewing this in…

  13. Biofortification of UK food crops with selenium.

    PubMed

    Broadley, Martin R; White, Philip J; Bryson, Rosie J; Meacham, Mark C; Bowen, Helen C; Johnson, Sarah E; Hawkesford, Malcolm J; McGrath, Steve P; Zhao, Fang-Jie; Breward, Neil; Harriman, Miles; Tucker, Mark

    2006-05-01

    Se is an essential element for animals. In man low dietary Se intakes are associated with health disorders including oxidative stress-related conditions, reduced fertility and immune functions and an increased risk of cancers. Although the reference nutrient intakes for adult females and males in the UK are 60 and 75 microg Se/d respectively, dietary Se intakes in the UK have declined from >60 microg Se/d in the 1970s to 35 microg Se/d in the 1990s, with a concomitant decline in human Se status. This decline in Se intake and status has been attributed primarily to the replacement of milling wheat having high levels of grain Se and grown on high-Se soils in North America with UK-sourced wheat having low levels of grain Se and grown on low-Se soils. An immediate solution to low dietary Se intake and status is to enrich UK-grown food crops using Se fertilisers (agronomic biofortification). Such a strategy has been adopted with success in Finland. It may also be possible to enrich food crops in the longer term by selecting or breeding crop varieties with enhanced Se-accumulation characteristics (genetic biofortification). The present paper will review the potential for biofortification of UK food crops with Se.

  14. Mesopotamian medicine.

    PubMed

    Retief, F P; Cilliers, L

    2007-01-01

    Although the Mesopotamian civilisation is as old as that of Egypt and might even have predated it, we know much less about Mesopotamian medicine, mainly because the cuneiform source material is less well researched. Medical healers existed from the middle of the 3rd millennium. In line with the strong theocratic state culture, healers were closely integrated with the powerful priestly fraternity, and were essentially of three main kinds: barû (seers) who were experts in divination, âshipu (exorcists), and asû (healing priests) who tended directly to the sick. All illness was accepted as sent by gods, demons and other evil spirits, either as retribution for sins or as malevolent visitations. Treatment revolved around identification of the offending supernatural power, appeasement of the angry gods, for example by offering amulets or incantations, exorcism of evil spirits, as well as a measure of empirical therapy aimed against certain recognised symptom complexes. Medical practice was rigidly codified, starting with Hammurabi's Code in the 18th century BC and persisting to the late 1st millennium BC. Works like the so-called Diagnostic Handbook, the Assyrian Herbal and Prescription Texts describe the rationale of Mesopotamian medicine, based predominantly on supernatural concepts, although rudimentary traces of empirical medicine are discernible. There is evidence that Egyptian medicine might have been influenced by Mesopotamian practices, but Greek rational medicine as it evolved in the 5th/4th centuries BC almost certainly had no significant Mesopotamian roots.

  15. Travel medicine

    PubMed Central

    Aw, Brian; Boraston, Suni; Botten, David; Cherniwchan, Darin; Fazal, Hyder; Kelton, Timothy; Libman, Michael; Saldanha, Colin; Scappatura, Philip; Stowe, Brian

    2014-01-01

    Abstract Objective To define the practice of travel medicine, provide the basics of a comprehensive pretravel consultation for international travelers, and assist in identifying patients who might require referral to travel medicine professionals. Sources of information Guidelines and recommendations on travel medicine and travel-related illnesses by national and international travel health authorities were reviewed. MEDLINE and EMBASE searches for related literature were also performed. Main message Travel medicine is a highly dynamic specialty that focuses on pretravel preventive care. A comprehensive risk assessment for each individual traveler is essential in order to accurately evaluate traveler-, itinerary-, and destination-specific risks, and to advise on the most appropriate risk management interventions to promote health and prevent adverse health outcomes during travel. Vaccinations might also be required and should be personalized according to the individual traveler’s immunization history, travel itinerary, and the amount of time available before departure. Conclusion A traveler’s health and safety depends on a practitioner’s level of expertise in providing pretravel counseling and vaccinations, if required. Those who advise travelers are encouraged to be aware of the extent of this responsibility and to refer all high-risk travelers to travel medicine professionals whenever possible. PMID:25500599

  16. Wilderness Medicine.

    PubMed

    Alexander, Whitney; Bright, Steven; Burns, Patrick; Townes, David

    2016-03-01

    Wilderness medicine encompasses prevention and treatment of illness and injury, education and training, emergency medical services, and search and rescue in the wilderness. Although traumatic injuries, including minor injuries, outnumber medical illness as the cause of morbidity in the wilderness, basic understanding of the prevention and management of injury and illness, including recognition, identification, treatment, initial management, and stabilization, is essential, in addition to the ability to facilitate evacuation of affected patients. An important theme throughout wilderness medicine is planning and preparation for the best- and worst-case scenarios, and being ready for the unexpected.

  17. Tobacco imagery on prime time UK television

    PubMed Central

    Lyons, Ailsa; McNeill, Ann; Britton, John

    2014-01-01

    Background Smoking in films is a common and well documented cause of youth smoking experimentation and uptake and hence a significant health hazard. The extent of exposure of young people to tobacco imagery in television programming has to date been far less investigated. We have therefore measured the extent to which tobacco content occurs in prime time UK television, and estimated exposure of UK youth. Methods The occurrence of tobacco, categorised as actual tobacco use, implied tobacco use, tobacco paraphernalia, other reference to tobacco, tobacco brand appearances or any of these, occurring in all prime time broadcasting on the five most popularly viewed UK television stations during 3 separate weeks in 2010 were measured by 1-minute interval coding. Youth exposure to tobacco content in the UK was estimated using media viewing figures. Findings Actual tobacco use, predominantly cigarette smoking, occurred in 73 of 613 (12%) programmes, particularly in feature films and reality TV. Brand appearances were rare, occurring in only 18 programmes, of which 12 were news or other factual genres, and 6 were episodes of the same British soap opera. Tobacco occurred with similar frequency before as after 21:00, the UK watershed for programmes suitable for youth. The estimated number of incidences of exposure of the audience aged less than 18 years for any tobacco, actual tobacco use and tobacco branding were 59 million, 16 million and 3 million, respectively on average per week. Conclusions Television programming is a source of significant exposure of youth to tobacco imagery, before and after the watershed. Tobacco branding is particularly common in Coronation Street, a soap opera popular among youth audiences. More stringent controls on tobacco in prime time television therefore have the potential to reduce the uptake of youth smoking in the UK. PMID:23479113

  18. Bullying and the UK Armed Forces.

    PubMed

    Coetzee, R H; Atkins, S; Gould, M

    2012-06-01

    There are certain characteristics of the culture and environment in the Armed Forces that may be conducive to bullying. In this article we examine the cultural and environmental factors that may encourage such behaviour and those that act as deterrents for victims to come forward. We will look at the scope of this problem within the UK Armed Forces specifically, before more generally considering the psychological impact of bullying. There appears to be an overall downward trend in bullying within the UK Armed Forces and a positive increase in complaints as more victims step forward. We conclude by highlighting some areas for further development.

  19. Is old medicine new medicine?

    PubMed

    Montaocean, K

    1991-07-01

    By the year 2000, over 90% of cases of acquired immunodeficiency syndrome (AIDS) are expected in Third World countries where Western medicine is often unavailable, unaffordable, or culturally unacceptable. Thus, there is a need for greater attention to the potential role of traditional medicine and healers in the prevention and treatment of AIDS. A US-based nongovernmental organization, Green Cross Inc, is examining cross-cultural healing traditions and seeking areas of convergence between scientific bio-medicine and indigenous traditional healing systems. At a street clinic operated by Green Cross in Washington DC, both Western medicine and traditional Chinese practices such as acupuncture, herbal remedies, and meditation are offered to AIDS patients at those at risk of infection. Although the individualized nature of Chinese medicine makes it difficult to evaluate through use of Western research methods, there is anecdotal evidence that it reduces the stress, anxiety, depression, and fatigue that accompany AIDS. Health care systems in all parts of the world could benefit from the concept that illness cannot be treated in isolation from individuals and communities.

  20. Are the birch trees in Southern England a source of Betula pollen for North London?

    PubMed

    Skjøth, C A; Smith, M; Brandt, J; Emberlin, J

    2009-01-01

    Birch pollen is highly allergenic. Knowledge of daily variations, atmospheric transport and source areas of birch pollen is important for exposure studies and for warnings to the public, especially for large cities such as London. Our results show that broad-leaved forests with high birch tree densities are located to the south and west of London. Bi-hourly Betula pollen concentrations for all the days included in the study, and for all available days with high birch pollen counts (daily average birch pollen counts>80 grains/m3), show that, on average, there is a peak between 1400 hours and 1600 hours. Back-trajectory analysis showed that, on days with high birch pollen counts (n=60), 80% of air masses arriving at the time of peak diurnal birch pollen count approached North London from the south in a 180 degree arc from due east to due west. Detailed investigations of three Betula pollen episodes, with distinctly different diurnal patterns compared to the mean daily cycle, were used to illustrate how night-time maxima (2200-0400 hours) in Betula pollen counts could be the result of transport from distant sources or long transport times caused by slow moving air masses. We conclude that the Betula pollen recorded in North London could originate from sources found to the west and south of the city and not just trees within London itself. Possible sources outside the city include Continental Europe and the Betula trees within the broad-leaved forests of Southern England.

  1. Access to primary care in Hong Kong, Greater London and New York City.

    PubMed

    Chau, Pui Hing; Woo, Jean; Gusmano, Michael K; Weisz, Daniel; Rodwin, Victor G; Chan, Kam Che

    2013-01-01

    We investigate avoidable hospital conditions (AHC) in three world cities as a way to assess access to primary care. Residents of Hong Kong are healthier than their counterparts in Greater London or New York City. In contrast to their counterparts in New York City, residents of both Greater London and Hong Kong face no financial barriers to an extensive public hospital system. We compare residence-based hospital discharge rates for AHC, by age cohorts, in these cities and find that New York City has higher rates than Hong Kong and Greater London. Hong Kong has the lowest hospital discharge rates for AHC among the population 15-64, but its rates are nearly as high as those in New York City among the population 65 and over. Our findings suggest that in contrast to Greater London, older residents in Hong Kong and New York face significant barriers in accessing primary care. In all three cities, people living in lower socioeconomic status neighborhoods are more likely to be hospitalized for an AHC, but neighborhood inequalities are greater in Hong Kong and New York than in Greater London.

  2. A price comparison of recently launched proprietary pharmaceuticals in the UK and the US

    PubMed Central

    Jørgensen, Jesper; Kefalas, Panos

    2016-01-01

    Objective To explore the relationship between prices charged by manufacturers of proprietary pharmaceuticals in the US and in the UK in recent years (2013–2016), expressed as a multiplier, and to detail to what extent this relationship differs for high-cost therapies used in smaller patient populations, as compared to lower-cost drugs. Methodology Therapies assessed by the Scottish Medicines Consortium (SMC) in the UK between 1 January 2013 and 1 June 2016 were identified; only in-patent therapies were included in the analysis (to avoid the impact of price erosion post patent expiry); results were grouped according to annual cost per patient (whether considered high-cost, i.e., >£2,500 per patient per year, or not) and the size of the UK target population [whether considered orphan (<32,000 patients per year), ultra-orphan (<1,000 patients per year), or not]. Publicly listed prices were obtained in the US and UK and were adjusted where necessary to estimate the prices charged by manufacturers in the respective countries. The difference in price (per unit of the same strength and formulation) was calculated as a multiplier between the US and UK prices for each of the therapies identified. Results Based on the methodological approach described, 88 therapies were identified and included in the analysis. The multiplier between the US and UK prices was 3.64 for therapies with an estimated annual cost <£2,500; this was reduced to 1.90 for higher-cost therapies. A downward trend was also evident in the subgroup analysis of the higher-cost therapies; as the estimated target patient populations reduced from >32,000 down to <1,000, the US/UK price multipliers reduced from 2.13 for the former to 1.48 for the latter. Conclusion Although pharmaceutical prices have been found to be on average substantially higher in the US compared to the UK, our findings suggest that this price discrepancy is smaller for higher-cost therapies targeting small patient populations

  3. Making clinical academic careers more attractive: views from questionnaire surveys of senior UK doctors

    PubMed Central

    Lambert, Trevor W; Goldacre, Michael J

    2015-01-01

    Summary Objectives To report on doctors’ reasons, as expressed to our research group, for choosing academic careers and on factors that would make a career in clinical academic medicine more attractive to them. Design Postal, email and web questionnaires. Setting UK. Participants A total of 6936 UK-trained doctors who graduated in 1996, 1999 and 2000. Main outcome measures Open-ended comments about a career in clinical academic medicine. Results Of doctors who provided reasons for pursuing a long-term career in clinical academic medicine, the main reasons were enjoyment of academic work and personal satisfaction, whether expressed directly in those terms, or in terms of intellectual stimulation, enjoyment of research, teaching and the advancement of medicine, and the job being more varied than and preferable to clinical work alone. Doctors’ suggestions for making clinical academic medicine more attractive included improved pay and job security, better funding of research, greater availability of academic posts, more dedicated time for research (and less service work) and more support and mentoring. Women were more likely than men to prioritise flexible working hours and part-time posts. Conclusions Medical schools could provide more information, as part of student teaching, about the opportunities for and realities of a career in clinical academic medicine. Women, in particular, commented that they lacked the role models and information which would encourage them to consider seriously an academic career. Employers could increase academic opportunities by allowing more time for teaching, research and study and should assess whether job plans make adequate allowance for academic work. PMID:26380103

  4. Long-term decline of the CO mixing ratio in SW London from 2000 to 2011: An example of policy success in improving air quality

    NASA Astrophysics Data System (ADS)

    Hernández Paniagua, I. Y.; Lowry, D.; Clemitshaw, K. C.; Nisbet, E. G.

    2013-12-01

    In situ measurements of atmospheric CO have been performed at Royal Holloway University of London (Egham, Surrey) since 2000 to 2011 and standardised using NOAA calibration gases. The CO has shown a marked and progressive decline since 2000 following the strict controls on vehicle emissions. A not linear decline was observed, but if linearised the decline rate was roughly 47 ppb per year in the 2000-2003 period, and 15 ppb per year post 2003. It agrees with the observed increment of 81% in the ratio CO2/CO from 2000 to 2011. There is a greater influence of anthropogenic emissions during weekdays when fossil fuel use and combustion processes are higher that at weekends. The seasonal cycle is driven by the temporal variation in meteorological conditions, changes in the combustion emissions and OH seasonality. The seasonal cycle shows maximum concentrations in winter and minimum in late summer. The largest seasonal amplitude observed, peak to trough, was 303.1 ppb in 2000 whereas the smallest was 128.3 ppb in 2011. The data set has been split into 8 categories (45°) using wind sector analysis. This shows that the greatest concentrations are recorded from the east and northeast sectors. The lowest concentrations were observed for air from the south and southwest sectors. Back trajectory and meteorological analysis of the data confirm that the main sources of CO are anthropogenic emissions from the Greater London area and the dense local road network to the East of the measurement site. Nowadays, compared with Mace Head (West Ireland) data, the CO measured at Egham is not far above Atlantic background levels during large periods of the year when prevailing S-SW winds reach the site. The results are consistent with MOPITT satellite observations and 'bottom-up' inventory results. The Egham record implies that controls on emissions subsequent to legislation have been extremely successful the UK.

  5. Medicines for sleep

    MedlinePlus

    Benzodiazepines; Sedatives; Hypnotics; Sleeping pills; Insomnia - medicines; Sleep disorder - medicines ... the-counter (OTC) sleeping pills contain antihistamines. These medicines are commonly used to treat allergies. While these ...

  6. Medicinal Plants.

    ERIC Educational Resources Information Center

    Phillipson, J. David

    1997-01-01

    Highlights the demand for medicinal plants as pharmaceuticals and the demand for health care treatments worldwide and the issues that arise from this. Discusses new drugs from plants, anticancer drugs, antiviral drugs, antimalarial drugs, herbal remedies, quality, safety, efficacy, and conservation of plants. Contains 30 references. (JRH)

  7. Medicine Handbook.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Office of the Professions.

    New York State education law, rules, and regulations concerning the practice of medicine are presented, along with requirements and procedures for obtaining licensure and first registration as a physician. State statutory provisions cover: duration and registration of a license, practice and regulation of the profession, supervision by the Board…

  8. Medicine Handbook.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Office of the Professions.

    A reference guide to laws, rules, and regulations that govern medical practice in New York State is presented. After an overview of professional regulation in the state, licensing requirements/procedures for medicine are described including education and postgraduate training requirements, state licensing examinations, and application…

  9. Nuclear medicine

    SciTech Connect

    Wagner, H.N. Jr.

    1986-10-17

    In 1985 and 1986 nuclear medicine became more and more oriented toward in vov chemistry, chiefly as a result of advances in positron emission tomography (PET). The most important trend was the extension of PET technology into the care of patients with brain tumors, epilepsy, and heart disease. A second trend was the increasing use of single-photon emission computed tomography (SPECT).

  10. Prophylaxis for blood-borne diseases during the London 7/7 mass casualty terrorist bombing: a review and the role of bioethics.

    PubMed

    Edwards, Dafydd S; Barnett-Vanes, A; Narayan, N; Patel, H D L

    2016-10-01

    The suicide bombings in London on 7 July 2005 resulted in a mass casualty situation. Over 50% of casualties were treated at the Royal London Hospital where clinicians witnessed large numbers of severely injured patients. In some casualties human biological foreign material was found embedded in the soft tissue originating from the suicide bombers or other casualties. This had the potential of placing individuals at risk of transmission of blood-borne diseases. Advances in the fields of medicine and biology have led to increased survivorship in the context of trauma and mass casualty incidents. This has resulted in the emergence of ethical scenarios surrounding patient management. A systematic review of the literature of the 7/7 bombings, and suicide bombings reported globally, where biological implantation is noted, was performed to examine the medicolegal issues arising during such attack. Twelve casualties with human tissue implanted were recorded in the 7/7 bombings. While all patients at risk were given prophylaxis based on recommendations by the Health Protection Agency, several ethical considerations surfaced as a result. In this paper, we compare the sequence of events and the management process of the victims of the 7/7 bombings and the evidence-based research regarding blood-borne infection transmission. Furthermore, it explores the ethical dilemmas, experienced by the senior author on 7/7, surrounding prophylaxis for blood-borne diseases and protocols to avoid confusion over best practice in future bombing incidents.

  11. Sir William Dunn (1833-1912): the man, his trust and his legacy to science and medicine.

    PubMed

    Sidebottom, Eric; Paul, Alison

    2006-02-01

    William Dunn had no direct connections with medicine. He belonged to that Victorian generation of Scottish pioneers who went overseas to make their fortunes and, yet, devoted their money to numerous charitable purposes, mainly at home in the UK. His family origins were modest; born in Paisley, near Glasgow on 1 September 1833, he died in 1912 with an estate valued at 1.3 million pounds sterling. His fortune was made from a large worldwide trading empire with roots in South Africa, where he emigrated as a young man of 19--but later controlled from London. In his will, dated 4 November 1908, the key clause was 'to advance the cause of Christianity, to benefit children and young people, to support hospitals and alleviate human suffering, to encourage education and promote emigration'. After making provision for about half the total, he left the remainder in the hands of trustees. They allotted about 120 small sums to hospitals, nursing homes, orphanages and like institutions, but then decided that larger projects would be more likely to be permanent memorials to Sir William. After consulting the President of the Royal Society, Sir William Hardy, and the Secretary of the Medical Research Committee, Sir Walter Fletcher, the trustees gave 210,000 pounds sterling in 1920 to Sir Frederick Gowland Hopkins in biochemistry in Cambridge and 100,000 pounds sterling in 1922 to Professor Georges Dreyer in pathology in Oxford. Between them, these two laboratories have 'spawned' nine Nobel Prize winners. The 'alleviation of human suffering' achieved would surely have pleased Sir William and his trustees.

  12. Respiratory medicine

    PubMed Central

    Pinnock, Hilary

    2004-01-01

    The General Medical Services (GMS) contract has focused the attention of United Kingdom (UK) general practitioners (GPs) on the provision of high quality routine care for patients with chronic disease.1 The quality markers defined by the contract endorse the need for objective diagnosis and structured care recommended by the British Thoracic Society/Scottish Intercollegiate Guideline Network (BTS–SIGN) guideline for the management of asthma and the National Institute for Clinical Excellence (NICE) guideline on the management of chronic obstructive pulmonary disease (COPD).2,3 In this paper the key recommendations of these guidelines and their implementation in the pragmatic world of general practice are discussed, with specific focus on diagnosis, monitoring, management, self-management and delivery of care. PMID:15239918

  13. MEDLINE in the UK: pioneering the past, present and future.

    PubMed

    Pritchard, Steve J; Weightman, Alison L

    2005-09-01

    This article provides a brief history of the development of the MEDLINE database and its huge impact within the UK, from its inception to the present time. The origins of MEDLINE can be traced back to a collection of books in the US Surgeon General's Office during the American Civil War and John Shaw Billings' decision, during 1867, to make this Library as complete as possible. From these beginnings, Index Medicus was developed in the early years of the 20th century, and electronic versions of the database began with the computerized on-demand search service MEDLARS in 1964 and then via CD-ROM and Internet Grateful Med to the web-based and free-to-all service, PubMed, in 1997. The response to PubMed was immediate and startling with usage increasing from 7 million searches per annum in 1996 to 400 million searches per annum in 2001 and the service continues to improve. MEDLINE providers are now offering mapping of natural language queries to the sophisticated indexing vocabulary (Medical Subject Headings, MeSH) and the provision of specific filters for different types of publication to improve searching efficiency, as well as links to full-text versions of the papers where available. The next steps are likely to involve an increased blurring of database and full-text boundaries, incorporating seamless access to the best available evidence within MEDLINE and a wide range of other information resources within a single search and to an increasing amount of full-text via various open-archive initiatives. As ever, the US National Library of Medicine is in the vanguard of research and further applications of its MEDLINE database for users within the UK will be awaited with great interest.

  14. The experiences of implementing generic medicine policy in eight countries: A review and recommendations for a successful promotion of generic medicine use

    PubMed Central

    Hassali, Mohamed Azmi; Alrasheedy, Alian A.; McLachlan, Andrew; Nguyen, Tuan Anh; AL-Tamimi, Saleh Karamah; Ibrahim, Mohamed Izham Mohamed; Aljadhey, Hisham

    2013-01-01

    Generic medicines are clinically interchangeable with original brand medicines and have the same quality, efficacy and safety profiles. They are, nevertheless, much cheaper in price. Thus, while providing the same therapeutic outcomes, generic medicines lead to substantial savings for healthcare systems. Therefore, the quality use of generic medicines is promoted in many countries. In this paper, we reviewed the role of generic medicines in healthcare systems and the experiences of promoting the use of generic medicines in eight selected countries, namely the United States (US), the United Kingdom (UK), Sweden, Finland, Australia, Japan, Malaysia and Thailand. The review showed that there are different main policies adopted to promote generic medicines such as generic substitution in the US, generic prescribing in the UK and mandatory generic substitution in Sweden and Finland. To effectively and successfully implement the main policy, different complementary policies and initiatives were necessarily introduced. Barriers to generic medicine use varied between countries from negative perceptions about generic medicines to lack of a coherent generic medicine policy, while facilitators included availability of information about generic medicines to both healthcare professionals and patients, brand interchangeability guidelines, regulations that support generic substitution by pharmacists, and incentives to both healthcare professionals and patients. PMID:25561861

  15. Airborne observed and receptor-oriented modelled urban increments of anthropogenic CO2, CO and NOX concentrations in the megacity of London in summer 2012

    NASA Astrophysics Data System (ADS)

    Font Font, Anna Maria; Morguí, Josep Anton; Lee, James; McQuaid, Jim B.; Barratt, Benjamin

    2014-05-01

    scaled emissions were used. Modelled urban increments of CO correlated well with observations of excess CO (R>0.81) with a slope close to 1:1 when using scaled emissions (0.69-1.10, 2σ). Modelled CO2ff correlated well with observed excess CO2 when using temporal scaled emissions (R=0.83) with a slope ranging from 0.58:1 to 0.99:1 (2σ). The CO/CO2ff ratio from modelled increments was 5.8±0.6 ppb ppm-1. Results show the CO/CO2ff ratio from observed excess abundances and from the EDGAR emissions inventory were in accordance for the city of London for the survey campaign. Future studies will involve using other emissions inventories such as the National Atmospheric Emissions Inventory (NAEI) for the UK and the London Atmospheric Emissions Inventory (LAEI); and model urban increments of other airborne campaigns.

  16. To Moscow with love: partial reconstruction of Vygotsky's trip to London.

    PubMed

    van der Veer, René; Zavershneva, Ekaterina

    2011-12-01

    The Russian psychologist Lev Vygotsky (1896-1934) left the Soviet Union only once to attend a conference on the education of the deaf in London. So far almost nothing was known about this trip, which took place in a period when Vygotsky was still completely unknown as a psychologist, both inside his own country and abroad. Making use of a newly discovered notebook, it proved possible to partially reconstruct Vygotsky's journey and stay in London. Vygotsky's very personal remarks show him to have been a very sensitive and spirited man, who was prey to strong emotions during the conference and afterwards. Rather surprisingly, Vygotsky's own paper about the education of the deaf was never presented during the conference and the stay in London appears to have had a limited value for his own scientific development.

  17. An analysis of population and social change in London wards in the 1980s.

    PubMed

    Congdon, P

    1989-01-01

    "This paper discusses the estimation and projection of small area populations in London, [England] and considers trends in intercensal social and demographic indices which can be calculated using these estimates. Information available annually on vital statistics and electorates is combined with detailed data from the Census Small Area Statistics to derive demographic component based population estimates for London's electoral wards over five year periods. The availability of age disaggregated population estimates permits derivation of small area social indicators for intercensal years, for example, of unemployment and mortality. Trends in spatial inequality of such indicators during the 1980s are analysed and point to continuing wide differentials. A typology of population and social indicators gives an indication of the small area distribution of the recent population turnaround in inner London, and of its association with other social processes such as gentrification and ethnic concentration."

  18. Tracer concentration profiles measured in central London as part of the REPARTEE campaign

    NASA Astrophysics Data System (ADS)

    Martin, D.; Petersson, K. F.; White, I. R.; Henshaw, S. J.; Nickless, G.; Lovelock, A.; Barlow, J. F.; Dunbar, T.; Wood, C. R.; Shallcross, D. E.

    2009-11-01

    There have been relatively few tracer experiments carried out that have looked at vertical plume spread in urban areas. In this paper we present results from cyclic perfluorocarbon tracer experiments carried out in 2006 and 2007 in central London centred on the BT Tower as part of the REPARTEE (Regent's Park and Tower Environmental Experiment) campaign. The height of the tower gives a unique opportunity to study dispersion over a large vertical gradient. These gradients are then compared with classical Gaussian profiles of the relevant stability classes over a range of distances as well as interpretation of data with reference to both anemometry and LIDAR measurements made. Data are then compared with an operational model and contrasted with data taken in central London as part of the DAPPLE campaign looking at dosage compared with non-dimensionalised distance from source. Such analysis illustrates the feasibility of the use of these empirical correlations over these prescribed distances in central London.

  19. Analytical calculations of frequency-dependent hypermagnetizabilities and Cotton-Mouton constants using London atomic orbitals

    NASA Astrophysics Data System (ADS)

    Thorvaldsen, Andreas J.; Ruud, Kenneth; Rizzo, Antonio; Coriani, Sonia

    2008-10-01

    We present the first gauge-origin-independent, frequency-dependent calculations of the hypermagnetizability anisotropy, which determines the temperature-independent contribution to magnetic-field-induced linear birefringence, the so-called Cotton-Mouton effect. A density-matrix-based scheme for analytical calculations of frequency-dependent molecular properties for self-consistent field models has recently been developed, which is also valid with frequency- and field-dependent basis sets. Applying this scheme to Hartree-Fock wave functions and using London atomic orbitals in order to obtain gauge-origin-independent results, we have calculated the hypermagnetizability anisotropy. Our results show that the use of London orbitals leads to somewhat better basis-set convergence for the hypermagnetizability compared to conventional basis sets and that London orbitals are mandatory in order to obtain reliable magnetizability anisotropies.

  20. Progressing Professional Careers in UK Higher Education

    ERIC Educational Resources Information Center

    Whitchurch, Celia

    2009-01-01

    This paper arises out of a study conducted for the Leadership Foundation for Higher Education on "Professional Managers in UK Higher Education: Preparing for Complex Futures," and focuses on those aspects relating to professional and career development. The author reviewed understandings in the literature about the roles and identities…

  1. Single heterostructure lasers: a UK perspective

    NASA Astrophysics Data System (ADS)

    Selway, Peter

    2012-09-01

    The gallium-aluminium-arsenide single heterostructure laser was the first commercially successful semiconductor laser produced in the UK. This paper presents a personal perspective on the events leading up to volume production and highlights the fascinating physics involved in this device and the impact of this on the task of engineering a robust component which was eventually manufactured for over 20 years.

  2. Globalisation and MATESOL Programmes in the UK

    ERIC Educational Resources Information Center

    Hasrati, Mostafa; Tavakoli, Parvaneh

    2015-01-01

    This article reports the results of a mixed-methods approach to investigating the association between globalisation and MATESOL in UK universities. Qualitative and quantitative data collected from academic staff through eight emails, four interviews and 41 questionnaires indicate that the globalised context of higher education has affected these…

  3. Accelerated technology transfer: the UK quantum initiative

    NASA Astrophysics Data System (ADS)

    Bennett, Simon D.

    2016-10-01

    A new generation of quantum technology based systems, exploiting effects such as superposition and entanglement, will enable widespread, highly disruptive applications which are expected to be of great economic significance. However, the technology is only just emerging from the physics laboratory and generally remains at low TRLs. The question is: where, and when, will this impact be first manifest? The UK, with substantial Government backing, has embarked on an ambitious national program to accelerate the process of technology transfer with the objective of seizing a significant and sustainable share of the future economic benefit for the UK. Many challenges and uncertainties remain but the combined and co-ordinated efforts of Government, Industry and Academia are making great progress. The level of collaboration is unusually high and the goal of embedding a "QT Ecosystem" in the UK looks to be attainable. This paper describes the UK national programme, its key players, and their respective roles. It will illustrate some of the likely first commercial applications and provide a status update. Some of the challenges that might prevent realisation of the goal will be highlighted.

  4. Cohort profile: UK Millennium Cohort Study (MCS).

    PubMed

    Connelly, Roxanne; Platt, Lucinda

    2014-12-01

    The UK Millennium Cohort Study (MCS) is an observational, multidisciplinary cohort study that was set up to follow the lives of children born at the turn of the new century. The MCS is nationally representative and 18 552 families (18 827 children) were recruited to the cohort in the first sweep. There have currently been five main sweeps of data collection, at ages 9 months and 3, 5, 7 and 11 years. A further sweep of data collection is planned for age 14 years. A range of health-related data have been collected as well as measures concerning child development, cognitive ability and educational attainment. The data also include a wealth of information describing the social, economic and demographic characteristics of the cohort members and their families. In addition, the MCS data have been linked to administrative data resources including health records. The MCS provides a unique and valuable resource for the analysis of health outcomes and health inequalities. The MCS data are freely available to bona fide researchers under standard access conditions via the UK Data Service (http://ukdataservice.ac.uk) and the MCS website provides detailed information on the study (http://www.cls.ioe.ac.uk/mcs).

  5. Challenges for Academic Accreditation: The UK Experience

    ERIC Educational Resources Information Center

    Shearman, Richard; Seddon, Deborah

    2010-01-01

    Several factors (government policy, demographic trends, employer pressure) are leading to new forms of degree programmes in UK universities. The government is strongly encouraging engagement between universities and employers. Work-based learning is increasingly found in first and second cycle programmes, along with modules designed by employers…

  6. Subject Choice and Earnings of UK Graduates

    ERIC Educational Resources Information Center

    Chevalier, Arnaud

    2011-01-01

    Using a survey of a cohort of UK graduates, linked to administrative data on higher education participation, this paper investigates the labour market attainment of recent graduates by subject of study. We document a large heterogeneity in the mean wages of graduates from different subjects and a considerably larger one within subject with…

  7. After Brexit: nursing a divided UK.

    PubMed

    Trueland, Jennifer

    2016-09-14

    Back in September 2014, the people of Scotland voted by 55% to 45% to stay part of the UK. Billed as a once in a generation event, the referendum appeared to put paid to the idea of an independent Scotland for the foreseeable future.

  8. Disability in the UK: Measuring Equality

    ERIC Educational Resources Information Center

    Purdam, Kingsley; Afkhami, Reza; Olsen, Wendy; Thornton, Patricia

    2008-01-01

    In this article we identify the key survey data for examining the issue of equality in the lives of disabled people in the UK. Such data is essential for assessing change in quality of life over time and for the evaluation of the impact of policy initiatives. For each data source we consider definitions, data collection, issue coverage, sample…

  9. Sunday Opening in UK Public Libraries

    ERIC Educational Resources Information Center

    Moore, Chris; Creaser, Claire

    2010-01-01

    This paper presents a summary of the first survey of public library authorities in the UK to explore Sunday opening, undertaken in 2007 as part of the Clore Leadership Programme. It provides a snapshot of Sunday opening practice, set against a context of societal, economic, and policy developments, and examines whether Sunday opening furthers the…

  10. Resources for Teaching Astronomy in UK Schools

    ERIC Educational Resources Information Center

    Roche, Paul; Newsam, Andy; Roberts, Sarah; Mason, Tom; Baruch, John

    2012-01-01

    This article looks at a selection of resources currently available for use in the teaching of astronomy in UK schools. It is by no means an exhaustive list but it highlights a variety of free resources that can be used in the classroom to help engage students of all ages with astronomy and space science. It also lists several facilities with a…

  11. Quality assurance in UK higher education

    NASA Astrophysics Data System (ADS)

    Shrimplin, Valerie

    Quality Assurance methods are becoming increasingly well known as systems applicable in business, commerce and industry. In modified form, such concepts can be applied to higher education and, in the UK, quality systems are utilized in universities in order to ensure the quality of provision and standards of awards. Similar principles may also be applied to the evaluation of quality in research.

  12. Ammonia emission factors for UK agriculture

    NASA Astrophysics Data System (ADS)

    Misselbrook, T. H.; Van Der Weerden, T. J.; Pain, B. F.; Jarvis, S. C.; Chambers, B. J.; Smith, K. A.; Phillips, V. R.; Demmers, T. G. M.

    Ammonia (NH 3) emission inventories are required for modelling atmospheric NH 3 transport and estimating downwind deposition. A recent inventory for UK agriculture, estimating emission as 197 kt NH 3-N yr -1, was constructed using 1993 statistical and census data for the UK. This paper describes the derivation of the UK-based emission factors used in the calculation of that emission for a range of livestock classes, farm practices and fertiliser applications to agricultural land. Some emission factors have been updated where more recent information has become available. Some of the largest emission factors derived for each farming practice include 16.9 g NH 3-N dairy cow -1 d -1 for grazing, 148.8 g NH 3-N liveweight unit -1 yr -1 for housed broilers and 4.8 g NH 3-N m -2 d -1 for storage of solid pig and poultry waste as manure heaps. Emissions for land spreading of all livestock waste were 59% of the total ammoniacal nitrogen (TAN) applied as a high dry matter content slurry and 76% of TAN applied as farm yard manure. An updated estimate of emission from UK agriculture, using updated emission factors together with 1997 statistical and census data, is presented, giving a total of 226 kt NH 3-N per year.

  13. Migrant cap 'may damage' UK physics

    NASA Astrophysics Data System (ADS)

    Harris, Margaret

    2011-01-01

    Scientists have expressed concern that changes to UK immigration rules - including a sharp drop in the number of visas available for the most highly skilled migrants - could make it more difficult for universities and other institutions to recruit talented researchers from overseas.

  14. IS Curriculum Career Tracks: A UK Study

    ERIC Educational Resources Information Center

    Stefanidis, Angelos; Fitzgerald, Guy; Counsell, Steve

    2013-01-01

    Purpose: The purpose of this paper is to present the results of a comprehensive study on the specialisations or career tracks supported by the Information Systems (IS) curriculum in the UK. Design/methodology/approach: The study utilises the recently published IS curriculum guidelines (IS 2010) to develop a method for ranking the career tracks of…

  15. Metaphor Use in Three UK University Lectures

    ERIC Educational Resources Information Center

    Low, Graham; Littlemore, Jeannette; Koester, Almut

    2008-01-01

    It has been claimed in recent years that, on the one hand, metaphor occurs in UK university lectures in ways that are likely to confuse ESL learners (Littlemore 2001, 2003) and on the other hand that US lecturers use it in highly structured ways, particularly involving linked clusters, to help organize the lecture and indicate the opinions of the…

  16. The epidemiology of injuries in powerlifting at the London 2012 Paralympic Games: An analysis of 1411 athlete-days.

    PubMed

    Willick, S E; Cushman, D M; Blauwet, C A; Emery, C; Webborn, N; Derman, W; Schwellnus, M; Stomphorst, J; Van de Vliet, P

    2016-10-01

    Sport injury epidemiology has received increased recognition as a field of sport medicine research that can improve the health and safety of athletes. Injuries among Paralympic powerlifters have not previously been systematically studied. The purpose of this prospective cohort study was to characterize injuries among Paralympic powerlifters. Athletes competing in the sport of powerlifting were followed over the 7-day competition period of the 2012 London Paralympic Games. The main outcome measurements were injury incidence rate (IR; number of injuries per 1000 athlete-days) and injury incidence proportion (IP; injuries per 100 athletes). A total of 38 injuries among 163 powerlifters were documented. The overall IR was 33.3 injuries/1000 athlete-days (95% CI 24.0-42.6) and the overall IP was 23.3 injuries per 100 athletes (95% CI 16.8-29.8). The majority of injuries were chronic overuse injuries (61%). The most commonly injured anatomical region was the shoulder/clavicle (32% of all injuries), followed by the chest (13%) and elbow (13%). The information obtained in this study opens the door for future study into the mechanisms and details of injuries into powerlifters with physical impairments.

  17. ‘By Merit Raised to That Bad Eminence’: Christopher Merrett, Artisanal Knowledge, and Professional Reform in Restoration London

    PubMed Central

    Mauck, Aaron

    2012-01-01

    This article examines the career and reform agenda of Christopher Merrett as a means of evaluating the changing conditions of medical knowledge production in late seventeenth-century London. This period was characterised by increasing competition between medical practitioners, resulting from the growing consumer demand for medical commodities and services, the reduced ability of elite physicians to control medical practice, and the appearance of alternative methods of producing medical knowledge – particularly experimental methods. This competition resulted in heated exchanges between physicians, apothecaries, and virtuosi, in which Merrett played an active part. As a prominent member of both the Royal Society and the Royal College of Physicians, Merrett sought to mediate between the two institutions by introducing professional reforms designed to alleviate competition and improve medical knowledge.These reforms entailed sweeping changes to medical regulation and education that integrated the traditional reliance on Galenic principles with knowledge derived from experiment and artisanal practices. The emphasis Merrett placed on the trades suggests the important role artisanal knowledge played in his efforts to reorganise medicine and improve knowledge of bodily processes. PMID:23752982

  18. {Semantic metadata application for information resources systematization in water spectroscopy} A.Fazliev (1), A.Privezentsev (1), J.Tennyson (2) (1) Institute of Atmospheric Optics SB RAS, Tomsk, Russia, (2) University College London, London, UK (faz@iao

    NASA Astrophysics Data System (ADS)

    Fazliev, A.

    2009-04-01

    The information and knowledge layers of information-computational system for water spectroscopy are described. Semantic metadata for all the tasks of domain information model that are the basis of the layers have been studied. The principle of semantic metadata determination and mechanisms of the usage during information systematization in molecular spectroscopy has been revealed. The software developed for the work with semantic metadata is described as well. Formation of domain model in the framework of Semantic Web is based on the use of explicit specification of its conceptualization or, in other words, its ontologies. Formation of conceptualization for molecular spectroscopy was described in Refs. 1, 2. In these works two chains of task are selected for zeroth approximation for knowledge domain description. These are direct tasks chain and inverse tasks chain. Solution schemes of these tasks defined approximation of data layer for knowledge domain conceptualization. Spectroscopy tasks solutions properties lead to a step-by-step extension of molecular spectroscopy conceptualization. Information layer of information system corresponds to this extension. An advantage of molecular spectroscopy model designed in a form of tasks chain is actualized in the fact that one can explicitly define data and metadata at each step of solution of these molecular spectroscopy chain tasks. Metadata structure (tasks solutions properties) in knowledge domain also has form of a chain in which input data and metadata of the previous task become metadata of the following tasks. The term metadata is used in its narrow sense: metadata are the properties of spectroscopy tasks solutions. Semantic metadata represented with the help of OWL 3 are formed automatically and they are individuals of classes (A-box). Unification of T-box and A-box is an ontology that can be processed with the help of inference engine. In this work we analyzed the formation of individuals of molecular spectroscopy applied ontologies as well as the software used for their creation by means of OWL DL language. The results of this work are presented in a form of an information layer and a knowledge layer in W@DIS information system 4. 1 FORMATION OF INDIVIDUALS OF WATER SPECTROSCOPY APPLIED ONTOLOGY Applied tasks ontology contains explicit description of input an output data of physical tasks solved in two chains of molecular spectroscopy tasks. Besides physical concepts, related to spectroscopy tasks solutions, an information source, which is a key concept of knowledge domain information model, is also used. Each solution of knowledge domain task is linked to the information source which contains a reference on published task solution, molecule and task solution properties. Each information source allows us to identify a certain knowledge domain task solution contained in the information system. Water spectroscopy applied ontology classes are formed on the basis of molecular spectroscopy concepts taxonomy. They are defined by constrains on properties of the selected conceptualization. Extension of applied ontology in W@DIS information system is actualized according to two scenarios. Individuals (ontology facts or axioms) formation is actualized during the task solution upload in the information system. Ontology user operation that implies molecular spectroscopy taxonomy and individuals is performed solely by the user. For this purpose Protege ontology editor was used. For the formation, processing and visualization of knowledge domain tasks individuals a software was designed and implemented. Method of individual formation determines the sequence of steps of created ontology individuals' generation. Tasks solutions properties (metadata) have qualitative and quantitative values. Qualitative metadata are regarded as metadata describing qualitative side of a task such as solution method or other information that can be explicitly specified by object properties of OWL DL language. Quantitative metadata are metadata that describe quantitative properties of task solution such as minimal and maximal data value or other information that can be explicitly obtained by programmed algorithmic operations. These metadata are related to DatatypeProperty properties of OWL specification language Quantitative metadata can be obtained automatically during data upload into information system. Since ObjectProperty values are objects, processing of qualitative metadata requires logical constraints. In case of the task solved in W@DIS ICS qualitative metadata can be formed automatically (for example in spectral functions calculation task). The used methods of translation of qualitative metadata into quantitative is characterized as roughened representation of knowledge in knowledge domain. The existence of two ways of data obtainment is a key moment in the formation of applied ontology of molecular spectroscopy task. experimental method (metadata for experimental data contain description of equipment, experiment conditions and so on) on the initial stage and inverse task solution on the following stages; calculation method (metadata for calculation data are closely related to the metadata used for the description of physical and mathematical models of molecular spectroscopy) 2 SOFTWARE FOR ONTOLOGY OPERATION Data collection in water spectroscopy information system is organized in a form of workflow that contains such operations as information source creation, entry of bibliographic data on publications, formation of uploaded data schema an so on. Metadata are generated in information source as well. Two methods are used for their formation: automatic metadata generation and manual metadata generation (performed by user). Software implementation of support of actions related to metadata formation is performed by META+ module. Functions of META+ module can be divided into two groups. The first groups contains the functions necessary to software developer while the second one the functions necessary to a user of the information system. META+ module functions necessary to the developer are: 1. creation of taxonomy (T-boxes) of applied ontology classes of knowledge domain tasks; 2. creation of instances of task classes; 3. creation of data schemes of tasks in a form of an XML-pattern and based on XML-syntax. XML-pattern is developed for instances generator and created according to certain rules imposed on software generator implementation. 4. implementation of metadata values calculation algorithms; 5. creation of a request interface and additional knowledge processing function for the solution of these task; 6. unification of the created functions and interfaces into one information system The following sequence is universal for the generation of task classes' individuals that form chains. Special interfaces for user operations management are designed for software developer in META+ module. There are means for qualitative metadata values updating during data reuploading to information source. The list of functions necessary to end user contains: - data sets visualization and editing, taking into account their metadata, e.g.: display of unique number of bands in transitions for a certain data source; - export of OWL/RDF models from information system to the environment in XML-syntax; - visualization of instances of classes of applied ontology tasks on molecular spectroscopy; - import of OWL/RDF models into the information system and their integration with domain vocabulary; - formation of additional knowledge of knowledge domain for the construction of ontological instances of task classes using GTML-formats and their processing; - formation of additional knowledge in knowledge domain for the construction of instances of task classes, using software algorithm for data sets processing; - function of semantic search implementation using an interface that formulates questions in a form of related triplets in order for getting an adequate answer. 3 STRUCTURE OF META+ MODULE META+ software module that provides the above functions contains the following components: - a knowledge base that stores semantic metadata and taxonomies of information system; - software libraries POWL and RAP 5 created by third-party developer and providing access to ontological storage; - function classes and libraries that form the core of the module and perform the tasks of formation, storage and visualization of classes instances; - configuration files and module patterns that allow one to adjust and organize operation of different functional blocks; META+ module also contains scripts and patterns implemented according to the rules of W@DIS information system development environment. - scripts for interaction with environment by means of the software core of information system. These scripts provide organizing web-oriented interactive communication; - patterns for the formation of functionality visualization realized by the scripts Software core of scientific information-computational system W@DIS is created with the help of MVC (Model - View - Controller) design pattern that allows us to separate logic of application from its representation. It realizes the interaction of three logical components, actualizing interactivity with the environment via Web and performing its preprocessing. Functions of «Controller» logical component are realized with the help of scripts designed according to the rules imposed by software core of the information system. Each script represents a definite object-oriented class with obligatory class method of script initiation called "start". Functions of actualization of domain application operation results representation (i.e. "View" component) are sets of HTML-patterns that allow one to visualize the results of domain applications operation with the help of additional constructions processed by software core of the system. Besides the interaction with the software core of the scientific information system this module also deals with configuration files of software core and its database. Such organization of work provides closer integration with software core and deeper and more adequate connection in operating system support. 4 CONCLUSION In this work the problems of semantic metadata creation in information system oriented on information representation in the area of molecular spectroscopy have been discussed. The described method of semantic metadata and functions formation as well as realization and structure of META+ module have been described. Architecture of META+ module is closely related to the existing software of "Molecular spectroscopy" scientific information system. Realization of the module is performed with the use of modern approaches to Web-oriented applications development. It uses the existing applied interfaces. The developed software allows us to: - perform automatic metadata annotation of calculated tasks solutions directly in the information system; - perform automatic annotation of metadata on the solution of tasks on task solution results uploading outside the information system forming an instance of the solved task on the basis of entry data; - use ontological instances of task solution for identification of data in information tasks of viewing, comparison and search solved by information system; - export applied tasks ontologies for the operation with them by external means; - solve the task of semantic search according to the pattern and using question-answer type interface. 5 ACKNOWLEDGEMENT The authors are grateful to RFBR for the financial support of development of distributed information system for molecular spectroscopy. REFERENCES A.D.Bykov, A.Z. Fazliev, N.N.Filippov, A.V. Kozodoev, A.I.Privezentsev, L.N.Sinitsa, M.V.Tonkov and M.Yu.Tretyakov, Distributed information system on atmospheric spectroscopy // Geophysical Research Abstracts, SRef-ID: 1607-7962/gra/EGU2007-A-01906, 2007, v. 9, p. 01906. A.I.Prevezentsev, A.Z. Fazliev Applied task ontology for molecular spectroscopy information resources systematization. The Proceedings of 9th Russian scientific conference "Electronic libraries: advanced methods and technologies, electronic collections" - RCDL'2007, Pereslavl Zalesskii, 2007, part.1, 2007, P.201-210. OWL Web Ontology Language Semantics and Abstract Syntax, W3C Recommendation 10 February 2004, http://www.w3.org/TR/2004/REC-owl-semantics-20040210/ W@DIS information system, http://wadis.saga.iao.ru RAP library, http://www4.wiwiss.fu-berlin.de/bizer/rdfapi/.

  19. Methane and nitrous oxide measurements onboard the UK Atmospheric Research Aircraft using quantum cascade laser spectrometry (QCL)

    NASA Astrophysics Data System (ADS)

    Muller, J. B.; O'Shea, S.; Dorsey, J.; Bauguitte, S.; Cain, M.; Allen, G.; Percival, C. J.; Gallagher, M. W.

    2012-12-01

    A Aerodyne Research© Mini-Quantum Cascade Laser (QCL) spectrometer was installed on the UK Facility of Airborne Atmospheric Measurements (FAAM) BAe-146 research aircraft and employed during summer 2012. Methane (CH4) and nitrous oxide (N2O) concentrations were measured within the Arctic Circle as part of the MAMM project (Methane and other greenhouse gases in the Arctic - Measurements, process studies and Modelling) as well as around the UK as part of the ClearfLo project (Clean Air for London). A range of missions were flown, including deep vertical profiles up to the stratosphere, providing concentration profiles of CH4 and N2O, as well as low altitude level runs exploring near surface diffuse emission sources such as the wetlands in Arctic Lapland and point emissions sources such as gas platforms off the UK coast. Significant pollution plumes were observed both in the Arctic and around the UK with elevated CH4 concentrations, as well as enhanced CO, O3 and aerosol levels. The NAME Lagrangian particle dispersion model will be used to investigate the origins of these CH4 plumes to identify the locations of the emissions sources. The first set of flights using QCL on the FAAM research aircraft have been successful and regular in-flight calibrations (high/low span) and target concentrations were used to determine instrument accuracy and precision. Additional data quality control checks could be made by comparison with an onboard Los Gatos Fast Greenhouse Gas Analyser (FGGA) for CO2 and CH4 and provide the basis for further instrument development and implementation for future Arctic MAMM flights during spring and summer 2013.

  20. Developing an Integrated Approach for Local Urban Climate Models in London from Neighbourhood to Street Scale

    NASA Astrophysics Data System (ADS)

    Bakkali, M.; Davies, M.; Steadman, J. P.

    2012-04-01

    We currently have an incomplete understanding of how weather varies across London and how the city's microclimate will intensify levels of heat, cold and air pollution in the future. There is a need to target priority areas of the city and to promote design guidance on climate change mitigation strategies. As a result of improvements in the accuracy of local weather data in London, an opportunity is emerging for designers and planners of the built environment to measure the impact of their designs on local urban climate and to enhance the designer's role in creating more informed design choices at an urban micro-scale. However, modelling the different components of the urban environment separately and then collating and comparing the results invariably leads to discrepancies in the output of local urban climate modelling tools designed to work at different scales. Of particular interest is why marked differences appear between the data extracted from local urban climate models when we change the scale of modelling from city to building scale. An example of such differences is those that have been observed in relation to the London Unified Model and London Site Specific Air Temperature model. In order to avoid these discrepancies we need a method for understanding and assessing how the urban environment impacts on local urban climate as a whole. A step to achieving this is by developing inter-linkages between assessment tools. Accurate information on the net impact of the urban environment on the local urban climate will in turn facilitate more accurate predictions of future energy demand and realistic scenarios for comfort and health. This paper will present two key topographies of London's urban environment that influence local urban climate: land use and street canyons. It will look at the possibilities for developing an integrated approach to modelling London's local urban climate from the neighbourhood to the street scale.