Transfection effect of microbubbles on cells in superposed ultrasound waves and behavior of cavitation bubble.

PubMed

Kodama, Tetsuya; Tomita, Yukio; Koshiyama, Ken-Ichiro; Blomley, Martin J K

2006-06-01

The combination of ultrasound and ultrasound contrast agents (UCAs) is able to induce transient membrane permeability leading to direct delivery of exogenous molecules into cells. Cavitation bubbles are believed to be involved in the membrane permeability; however, the detailed mechanism is still unknown. In the present study, the effects of ultrasound and the UCAs, Optison on transfection in vitro for different medium heights and the related dynamic behaviors of cavitation bubbles were investigated. Cultured CHO-E cells mixed with reporter genes (luciferase or beta-gal plasmid DNA) and UCAs were exposed to 1 MHz ultrasound in 24-well plates. Ultrasound was applied from the bottom of the well and reflected at the free surface of the medium, resulting in the superposition of ultrasound waves within the well. Cells cultured on the bottom of 24-well plates were located near the first node (displacement node) of the incident ultrasound downstream. Transfection activity was a function determined with the height of the medium (wave traveling distance), as well as the concentration of UCAs and the exposure time was also determined with the concentration of UCAs and the exposure duration. Survival fraction was determined by MTT assay, also changes with these values in the reverse pattern compared with luciferase activity. With shallow medium height, high transfection efficacy and high survival fraction were obtained at a low concentration of UCAs. In addition, capillary waves and subsequent atomized particles became significant as the medium height decreased. These phenomena suggested cavitation bubbles were being generated in the medium. To determine the effect of UCAs on bubble generation, we repeated the experiments using crushed heat-treated Optison solution instead of the standard microbubble preparation. The transfection ratio and survival fraction showed no additional benefit when ultrasound was used. These results suggested that cavitation bubbles created by the collapse of UCAs were a key factor for transfection, and their intensities were enhanced by the interaction of the superpose ultrasound with the decreasing the height of the medium. Hypothesizing that free cavitation bubbles were generated from cavitation nuclei created by fragmented UCA shells, we carried out numerical analysis of a free spherical bubble motion in the field of ultrasound. Analyzing the interaction of the shock wave generated by a cavitation bubble and a cell membrane, we estimated the shock wave propagation distance that would induce cell membrane damage from the center of the cavitation bubble.

Flow-permeability feedbacks and the development of segregation pipes in volcanic materials

NASA Astrophysics Data System (ADS)

Rust, Alison

2014-05-01

Flow and transformation in volcanic porous media is important for the segregation of melts and aqueous fluids from magmas as well as elutriation of fine ash from pyroclastic flows and vents. The general topic will be discussed in the framework of understanding sets of vertical pipes found in two very different types of volcanic deposits: 1) vesicular (bubbly) cylinders in basalt lava flows and 2) gas escape pipes in pyroclastic flow deposits. In both cases the cylinders can be explained by a flow-permeability feedback where perturbations in porosity and thus permeability cause locally higher flow speeds that in turn locally increase the permeability. For vesicular cylinders in lava flows, the porous medium is a framework of crystals within the magma. Above a critical crystallinity, which depends on the shape and size distribution of the crystals, the crystals form a touching framework. As the water-saturated magma continues to cool, it crystallizes anhydrous minerals, resulting in the exsolution of water vapour bubbles that can drive flow of bubbly melt through the crystal network. It is common to find sets of vertical cylinders of bubby melt in solidified lava flows, with compositions that match the residual melt from 35-50% crystallization of the host basalt. These cylinders resemble chimneys in experiments of crystallising ammonium chloride solution that are explained by reactive flow with porous medium convection. The Rayleigh number for the magmatic case is too low for convection but the growth of steam bubbles as the magma crystallizes induces pore fluid flow up through the permeable crystal pile even if there is no convective instability. This bubble-growth-driven upward flow is reactive and can lead to channelization because of a feedback between velocity and permeability. For the gas escape pipes in pyroclastic flows, the porous medium is a very poorly sorted granular material composed of fragments of solid magma with a huge range of grain sizes from ash (microns to 2 mm) to clasts of decimeters or greater. The vertical gas escape pipes are distinguished from the surrounding pyroclastic flow deposit by the lack of fine ash in the pipes; this missing ash was transported up out of the pyroclastic flow by gas flow, a process called elutriation. Laboratory experiments with beds of binary mixtures of spheres aerated through a porous plate at the base, demonstrate that the size ratio, density ratio, and proportions of the two populations of spheres all affect the pattern and efficiency of segregation. Decompaction of the upper portion of the bed separates the grains and thus facilitated the elutriation of the finer particles, which must be transported up through the spaces between the larger particles. A variety of segregation feature are found including pipes lacking fines that grow down from the top of the bed. These could be explained by channelizing of gas flow due to a feedback between local reduction in fines increasing the local permeability and gas velocity.

Theoretical Investigation on Particle Brownian Motion on Micro-air-bubble Characteristic in H2O Solvent

NASA Astrophysics Data System (ADS)

Eka Putri, Irana; Gita Redhyka, Grace

2017-07-01

Micro-air-bubble has a high potential contribution in waste water, farming, and fishery treatment. In this research, submicron scale of micro-air-bubble was observed to determine its stability in H2O solvent. By increasing its stability, it can be used for several applications, such as bio-preservative for medical and food transport. The micro-air-bubble was assumed in spherical shape that in incompressible gas boundary condition. So, the random motion of particle (Brownian motion) can be solved by using Stokes-Einstein approximation. But, Hadamard and Rybczynski equation is promoted to solve for larger bubble (micro scale). While, the effect of physical properties (e.g. diffusion coefficient, density, and flow rate) have taken important role in its characteristics in water. According to the theoretical investigation that have been done, decreasing of bubble velocity indicates that the bubble dissolves away or shrinking to the surface. To obtain longevity bubble in pure water medium, it is recomended to apply some surfactant molecules (e.g. NaCl) in micro-air-bubble medium.

The XMM-Newton View of Wolf-Rayet Bubbles

NASA Astrophysics Data System (ADS)

Guerrero, M.; Toala, J.

2017-10-01

The powerful stellar winds of Wolf-Rayet (WR) stars blow large bubble into the circumstellar material ejected in previous phases of stellar evolution. The shock of those stellar winds produces X-ray-emitting hot plasmas which tells us about the diffusion of processed material onto the interstellar medium, about processes of heat conduction and turbulent mixing at the interface, about the late stages of stellar evolution, and about the shaping of the circumstellar environment, just before supernova explosions. The unique sensitivity of XMM-Newton has been key for the detection, mapping and spectral analysis of the X-ray emission from the hot bubbles around WR stars. These observations underscore the importance of the structure of the interstellar medium around massive stars, but they have also unveiled unknown phenomena, such as blowouts of hot gas into the interstellar medium or spatially-resolved spectral properties of the hot gas, which disclose inhomogeneous chemical abundances and physical properties across these bubbles.

Interstellar heliospheric probe/heliospheric boundary explorer mission—a mission to the outermost boundaries of the solar system

NASA Astrophysics Data System (ADS)

Wimmer-Schweingruber, Robert F.; McNutt, Ralph; Schwadron, Nathan A.; Frisch, Priscilla C.; Gruntman, Mike; Wurz, Peter; Valtonen, Eino

2009-05-01

The Sun, driving a supersonic solar wind, cuts out of the local interstellar medium a giant plasma bubble, the heliosphere. ESA, jointly with NASA, has had an important role in the development of our current understanding of the Suns immediate neighborhood. Ulysses is the only spacecraft exploring the third, out-of-ecliptic dimension, while SOHO has allowed us to better understand the influence of the Sun and to image the glow of interstellar matter in the heliosphere. Voyager 1 has recently encountered the innermost boundary of this plasma bubble, the termination shock, and is returning exciting yet puzzling data of this remote region. The next logical step is to leave the heliosphere and to thereby map out in unprecedented detail the structure of the outer heliosphere and its boundaries, the termination shock, the heliosheath, the heliopause, and, after leaving the heliosphere, to discover the true nature of the hydrogen wall, the bow shock, and the local interstellar medium beyond. This will greatly advance our understanding of the heliosphere that is the best-known example for astrospheres as found around other stars. Thus, IHP/HEX will allow us to discover, explore, and understand fundamental astrophysical processes in the largest accessible plasma laboratory, the heliosphere.

Numerical simulation of bubble plumes and an analysis of their seismic attributes

NASA Astrophysics Data System (ADS)

Li, Canping; Gou, Limin; You, Jiachun

2017-04-01

To study the bubble plume's seismic response characteristics, the model of a plume water body has been built in this article using the bubble-contained medium acoustic velocity model and the stochastic medium theory based on an analysis of both the acoustic characteristics of a bubble-contained water body and the actual features of a plume. The finite difference method is used for forward modelling, and the single-shot seismic record exhibits the characteristics of a scattered wave field generated by a plume. A meaningful conclusion is obtained by extracting seismic attributes from the pre-stack shot gather record of a plume. The values of the amplitude-related seismic attributes increase greatly as the bubble content goes up, and changes in bubble radius will not cause seismic attributes to change, which is primarily observed because the bubble content has a strong impact on the plume's acoustic velocity, while the bubble radius has a weak impact on the acoustic velocity. The above conclusion provides a theoretical reference for identifying hydrate plumes using seismic methods and contributes to further study on hydrate decomposition and migration, as well as on distribution of the methane bubble in seawater.

Long-Range Capture and Delivery of Water-Dispersed Nano-objects by Microbubbles Generated on 3D Plasmonic Surfaces.

PubMed

Tantussi, Francesco; Messina, Gabriele C; Capozza, Rosario; Dipalo, Michele; Lovato, Laura; De Angelis, Francesco

2018-05-22

The possibility of investigating small amounts of molecules, moieties, or nano-objects dispersed in solution constitutes a central step for various application areas in which high sensitivity is necessary. Here, we show that the rapid expansion of a water bubble can act as a fast-moving net for molecules or nano-objects, collecting the floating objects in the surrounding medium in a range up to 100 μm. Thanks to an engineered 3D patterning of the substrate, the collapse of the bubble could be guided toward a designed area of the surface with micrometric precision. Thus, a locally confined high density of particles is obtained, ready for evaluation by most optical/spectroscopic detection schemes. One of the main relevant strengths of the long-range capture and delivery method is the ability to increase, by a few orders of magnitude, the local density of particles with no changes in their physiological environment. The bubble is generated by an ultrafast IR laser pulse train focused on a resonant plasmonic antenna; due to the excitation process, the technique is trustworthy and applicable to biological samples. We have tested the reliabilities of the process by concentrating highly dispersed fluorescence molecules and fluorescent beads. Lastly, as an ultimate test, we have applied the bubble clustering method on nanosized exosome vesicles dispersed in water; due to the clustering effect, we were able to effectively perform Raman spectroscopy on specimens that were otherwise extremely difficult to measure.

The X-ray Emitting Components towards l = 111 deg: The Local Hot Bubble and Beyond

NASA Technical Reports Server (NTRS)

Kuntz, K. D.; Snowden, S. L.

2006-01-01

We have obtained an XMM-Newton spectrum of the diffuse X-ray emission towards (l, b) = (111.14,1.11), a line of sight with a relatively simple distribution of absorbing clouds; > 9 x 10(exp 19)/sq cm at R>170 pc, a 6 x 10(exp 21)/sq cm molecular cloud at 2.5-3.3 kpc, and a total column of 1.2 x 10(exp 22)/sq cm. We find that the analysis of the XMM-Newton spectrum in conjunction with the RASS spectral energy distribution for the same direction requires three thermal components to be well fit: a "standard" Local Hot Bubble component with kT = 0.089, a component beyond the molecular cloud with kT = 0.59, and a component before the molecular cloud with kT = 0.21. The strength of the O VII 0.56 keV line from the Local Hot Bubble, 2.1+/-0.7 photons/sq cm/s/sr, is consistent with other recent measures. The 0.21 keV component has an emission measure of 0.0022+/-0.0006 pc and is not localized save as diffuse emission within the Galactic plane; it is the best candidate for a pervasive hot medium. The spatial separation of the approx. 0.2 keV component from the approx. 0.6 keV component suggests that the spectral decompositions of the emission from late-type spiral disks found in the literature do represent real temperature components rather than reflecting more complex temperature distributions.

Radiation-pressure-driven dust waves inside bursting interstellar bubbles

NASA Astrophysics Data System (ADS)

Ochsendorf, B. B.; Verdolini, S.; Cox, N. L. J.; Berné, O.; Kaper, L.; Tielens, A. G. G. M.

2014-06-01

Massive stars drive the evolution of the interstellar medium through their radiative and mechanical energy input. After their birth, they form "bubbles" of hot gas surrounded by a dense shell. Traditionally, the formation of bubbles is explained through the input of a powerful stellar wind, even though direct evidence supporting this scenario is lacking. Here we explore the possibility that interstellar bubbles seen by the Spitzer- and Herschel space telescopes, blown by stars with log (L/L⊙) ≲ 5.2, form and expand because of the thermal pressure that accompanies the ionization of the surrounding gas. We show that density gradients in the natal cloud or a puncture in the swept-up shell lead to an ionized gas flow through the bubble into the general interstellar medium, which is traced by a dust wave near the star, which demonstrates the importance of radiation pressure during this phase. Dust waves provide a natural explanation for the presence of dust inside H II bubbles, offer a novel method to study dust in H II regions and provide direct evidence that bubbles are relieving their pressure into the interstellar medium through a champagne flow, acting as a probe of the radiative interaction of a massive star with its surroundings. We explore a parameter space connecting the ambient density, the ionizing source luminosity, and the position of the dust wave, while using the well studied H II bubbles RCW 120 and RCW 82 as benchmarks of our model. Finally, we briefly examine the implications of our study for the environments of super star clusters formed in ultraluminous infrared galaxies, merging galaxies, and the early Universe, which occur in very luminous and dense environments and where radiation pressure is expected to dominate the dynamical evolution.

Synchrotron radiation and diffusive shock acceleration - A short review and GRB perspective

NASA Astrophysics Data System (ADS)

Karlica, Mile

2015-12-01

In this talk we present the sponge" model and its possible implications on the GRB afterglow light curves. "Sponge" model describes source of GRB afterglow radiation as fragmented GRB ejecta where bubbles move through the rarefied medium. In the first part of the talk a short introduction to synchrotron radiation and Fermi acceleration was presented. In the assumption that X-ray luminosity of GRB afterglow phase comes from the kinetic energy losses of clouds in ejecta medium radiated as synchrotron radiation we solved currently very simple equation of motion to find which combination of cloud and medium regime describes the afterglow light curve the best. We proposed for the first step to watch simple combinations of expansion regimes for both bubbles and surrounding medium. The closest case to the numerical fit of GRB 150403A with time power law index k = 1.38 is the combination of constant bubbles and Sedov like expanding medium with time power law index k = 1.25. Of course the question of possible mixture of variuos regime combinations is still open within this model.

Geyser preplay and eruption in a laboratory model with a bubble trap

NASA Astrophysics Data System (ADS)

Adelstein, Esther; Tran, Aaron; Saez, Carolina Muñoz; Shteinberg, Alexander; Manga, Michael

2014-09-01

We present visual observations and temperature measurements from a laboratory model of a geyser. Our model incorporates a bubble trap, a zone in which vapor can accumulate in the geyser's subsurface plumbing, in a vertical conduit connected to a basal chamber. Analogous features have been identified at several natural geysers. We observe three types of eruptions: 1) rising bubbles eject a small volume of liquid in a weak spout (small eruption); 2) boiling occurs in the conduit above the bubble trap (medium eruption); and 3) boiling occurs in the conduit and chamber (large eruption). In the last two cases, boiling in the conduit causes a rapid hydrostatic pressure drop that allows for the rise and eruption of liquid water in a vigorous spout. Boiling initiates at depth rather than propagating downward from the surface. In a single eruption cycle, multiple small eruptions precede every medium and large eruption. At least one eruption cycle that culminates in a medium eruption (i.e., a quiescent period followed by a series of small eruptions leading up to a medium eruption) precedes every eruption cycle that culminates in a large eruption. We find that the transfer of fluid with high enthalpy to the upper conduit during small and medium eruptions is necessary to heat the upper conduit and prepare the system for the full boiling required for a large eruption. The placement of the bubble trap midway up the conduit allows for more efficient heating of the upper conduit. Our model provides insight into the influence of conduit geometry on eruption style and the importance of heat transfer by smaller events in preparing the geyser system for eruption.

Transient thermal driven bubble's surface and its potential ultrasound-induced damage

NASA Astrophysics Data System (ADS)

Movahed, Pooya; Freund, Jonathan B.

2017-11-01

Ultrasound-induced bubble activity in soft tissues is well-known to be a potential injury mechanism in therapeutic ultrasound treatments. We consider damage by transient thermal effects, including a hypothetical mechanism based on transient thermal phenomena, including viscous dissipation. A spherically symmetric compressible Navier-Stokes discretization is developed to solve the full governing equations, both inside and outside of the bubble, without the usual simplifications in the Rayleigh-Plesset bubble dynamics approach. Equations are solved in the Lagrangian framework, which provides a sharp and accurate representation of the interface as well as the viscous dissipation and thermal transport effects, which preclude reduction to the usual Rayleigh-Plesset ordinary differential equation. This method is used to study transient thermal effects at different frequencies and pressure amplitudes relevant to therapeutic ultrasound treatments. High temperatures achieved in the surrounding medium during the violent bubble collapse phase due to the viscous dissipation in the surrounding medium and thermal conduction from the bubble are expected to cause damage. This work was supported by NIH NIDDK Grant P01-DK043881.

A hydrodynamical model of the circumstellar bubble created by two massive stars

NASA Astrophysics Data System (ADS)

van Marle, A. J.; Meliani, Z.; Marcowith, A.

2012-05-01

Context. Numerical models of the wind-blown bubble of massive stars usually only account for the wind of a single star. However, since massive stars are usually formed in clusters, it would be more realistic to follow the evolution of a bubble created by several stars. Aims: We develop a two-dimensional (2D) model of the circumstellar bubble created by two massive stars, a 40 M⊙ star and a 25 M⊙ star, and follow its evolution. The stars are separated by approximately 16 pc and surrounded by a cold medium with a density of 20 particles per cm3. Methods: We use the MPI-AMRVAC hydrodynamics code to solve the conservation equations of hydrodynamics on a 2D cylindrical grid using time-dependent models for the wind parameters of the two stars. At the end of the stellar evolution (4.5 and 7.0 million years for the 40 and 25 M⊙ stars, respectively), we simulate the supernova explosion of each star. Results: Each star initially creates its own bubble. However, as the bubbles expand they merge, creating a combined, aspherical bubble. The combined bubble evolves over time, influenced by the stellar winds and supernova explosions. Conclusions: The evolution of a wind-blown bubble created by two stars deviates from that of the bubbles around single stars. In particular, once one of the stars has exploded, the bubble is too large for the wind of the remaining star to maintain and the outer shell starts to disintegrate. The lack of thermal pressure inside the bubble also changes the behavior of circumstellar features close to the remaining star. The supernovae are contained inside the bubble, which reflects part of the energy back into the circumstellar medium. Movies are available in electronic form at http://www.aanda.org

Compton scattering of the microwave background by quasar-blown bubbles

NASA Technical Reports Server (NTRS)

Voit, G. Mark

1994-01-01

At least 10% of quasars drive rapid outflows from the central regions of their host galaxies. The mass and energy flow rates in these winds are difficult to measure, but their kinetic luminosities probably exceed 10(exp 45) ergs/s. This kind of outflow easily sunders the interstellar medium of the host and blows a bubble in the intergalactic medium. After the quasar shuts off, the hot bubble continues to shock intergalactic gas until its leading edge merges with the Hubble flow. The interior hot gas Compton scatters microwave background photons, potentially providing a way to detect these bubbles. Assuming that quasar kinetic luminosities scale with their blue luminosities, we integrate over the quasar luminosity function to find the total distortion (y) of the microwave background produced by the entire population of quasar wind bubbles. This calculation of y distortion is remarkably insensitive to the properties of the intergalactic medium (IGM), quasar lifetimes, and cosmological parameters. Current Cosmic Background Explorer (COBE) limits on y constrain the kinetic luminosities of quasars to be less than several times their bolometric radiative luminosities. Within this constraint, quasars can still expel enough kinetic luminosity to shock the entire IGM by z = 0, but cannot heat and ionize the IGM by z = 4 unless omega(sub IGM) much less than 10(exp -2).

A real-time controller for sustaining thermally relevant acoustic cavitation during ultrasound therapy.

PubMed

Hockham, Natalie; Coussios, Constantin C; Arora, Manish

2010-12-01

A novel method for sustaining inertial cavitation during high-intensity focused ultrasound (HIFU) exposure in an agar-based tissue-mimicking material is presented. Inertial cavitation occurs during HIFU therapy when the local rarefaction pressure exceeds the inertial cavitation threshold of the insonated medium, and is characterized by broadband acoustic emissions which can be easily detected non-invasively using a passive cavitation detector (PCD). Under the right conditions, inertial cavitation has been previously shown to greatly enhance the rate of heat deposition by redistributing part of the energy carried at the fundamental HIFU frequency to higher frequencies, which are more readily absorbed by visco-elastic media such as soft tissue. However, in the absence of any cavitation control, inertial cavitation activity at the focus decays rapidly over a few seconds of exposure because of the combined effects of cavitation nuclei depletion, bubble dissolution, bubble-bubble interactions, increased vapor pressure caused by heating, and focal shielding caused by pre-focal bubble activity. The present work describes the design, validation, and testing of a real-time adaptive controller, with integrated passive localization capabilities, for sustaining inertial cavitation within the focal region of a HIFU transducer by modulation of the HIFU amplitude. Use of the controller in agar gel, originally at room temperature, has enabled therapeutically relevant temperatures in excess of 55°C to be maintained continuously in the focal region for more than 20 s using significantly less acoustic energy than is required to achieve the same temperature rise in the absence of cavitation control.

Impact of methane flow through deformable lake sediments on atmospheric release

NASA Astrophysics Data System (ADS)

Scandella, B.; Juanes, R.

2010-12-01

Methane is a potent greenhouse gas that is generated geothermally and biologically in lake and ocean sediments. Free gas bubbles may escape oxidative traps and contribute more to the atmospheric source than dissolved methane, but the details of the methane release depend on the interactions between the multiple fluid phases and the deformable porous medium. We present a model and supporting laboratory experiments of methane release through “breathing” dynamic flow conduits that open in response to drops in the hydrostatic load on lake sediments, which has been validated against a high-resolution record of free gas flux and hydrostatic pressure in Upper Mystic Lake, MA. In contrast to previous linear elastic fracture mechanics analysis of gassy sediments, the evolution of gas transport in a deformable compliant sediment is presented within the framework of multiphase poroplasticity. Experiments address how strongly the mode and rate of gas flow, captured by our model, impacts the size of bubbles released into the water column. A bubble's size in turn determines how efficiently it transports methane to the atmosphere, and integrating this effect will be critical to improving estimates of the atmospheric methane source from lakes. Cross-sectional schematic of lake sediments showing two venting sites: one open at left and one closed at right. The vertical release of gas bubbles (red) at the open venting site creates a local pressure drop, which drives both bubble formation from the methane-rich pore water (higher concentrations shaded darker red) and lateral advection of dissolved methane (purple arrows). Even as bubbles in the open site escape, those at the closed site remain trapped.

Attenuation of the Acoustic Signal Propagating Through a Bubbly Liquid Layer

NASA Astrophysics Data System (ADS)

Gubaidullin, D. A.; Nikiforov, A. A.

2018-01-01

The acoustic signal dynamics in a five-layer medium containing two liquid layers with polydisperse gas bubbles has been investigated. Calculations have been made for the interaction between the pulse perturbation of smallamplitude pressure and a multilayer sample containing two layers of industrial gel with polydisperse air bubbles. It has been shown that a small content of bubbles (about 0.1 vol. %) in a thin gel layer decreases tenfold or more the amplitude of acoustic waves with frequencies close to the resonance frequency of natural oscillations of bubbles. There are frequency ranges thereby where the influence of the bubbly layer is insignificant.

Revising the Local Bubble Model due to Solar Wind Charge Exchange X-ray Emission

NASA Astrophysics Data System (ADS)

Shelton, Robin L.

The hot Local Bubble surrounding the solar neighborhood has been primarily studied through observations of its soft X-ray emission. The measurements were obtained by attributing all of the observed local soft X-rays to the bubble. However, mounting evidence shows that the heliosphere also produces diffuse X-rays. The source is solar wind ions that have received an electron from another atom. The presence of this alternate explanation for locally produced diffuse X-rays calls into question the existence and character of the Local Bubble. This article addresses these questions. It reviews the literature on solar wind charge exchange (SWCX) X-ray production, finding that SWCX accounts for roughly half of the observed local 1/4 keV X-rays found at low latitudes. This article also makes predictions for the heliospheric O VI column density and intensity, finding them to be smaller than the observational error bars. Evidence for the continued belief that the Local Bubble contains hot gas includes the remaining local 1/4 keV intensity, the observed local O VI column density, and the need to fill the local region with some sort of plasma. If the true Local Bubble is half as bright as previously thought, then its electron density and thermal pressure are 1/sqrt{2} as great as previously thought, and its energy requirements and emission measure are 1/2 as great as previously thought. These adjustments can be accommodated easily, and, in fact, bring the Local Bubble's pressure more in line with that of the adjacent material. Suggestions for future work are made.

Bubbles in Sediments

DTIC Science & Technology

1999-09-30

saturated poroelastic medium. The transition matrix scattering formalism was used to develop the scattered acoustic field(s) such that appropriate...sediment increases from a fluid model (simplest) to a fluid-saturated poroelastic model (most complex). Laboratory experiments in carefully quantified...of a linear acoustic field from a bubble, collection of bubbles, or other targets embedded in a fluid-saturated sediment are not well known. This

Cavitation in confined water: ultra-fast bubble dynamics

NASA Astrophysics Data System (ADS)

Vincent, Olivier; Marmottant, Philippe

2012-02-01

In the hydraulic vessels of trees, water can be found at negative pressure. This metastable state, corresponding to mechanical tension, is achieved by evaporation through a porous medium. It can be relaxed by cavitation, i.e. the sudden nucleation of vapor bubbles. Harmful for the tree due to the subsequent emboli of sap vessels, cavitation is on the contrary used by ferns to eject spores very swiftly. We will focus here on the dynamics of the cavitation bubble, which is of primary importance to explain the previously cited natural phenomena. We use the recently developed method of artificial tress, using transparent hydrogels as the porous medium. Our experiments, on water confined in micrometric hydrogel cavities, show an extremely fast dynamics: bubbles are nucleated at the microsecond timescale. For cavities larger than 100 microns, the bubble ``rings'' with damped oscillations at MHz frequencies, whereas for smaller cavities the oscillations become overdamped. This rich dynamics can be accounted for by a model we developed, leading to a modified Rayleigh-Plesset equation. Interestingly, this model predicts the impossibility to nucleate bubbles above a critical confinement that depends on liquid negative pressure and corresponds to approximately 100 nm for 20 MPa tensions.

Study on the bubble transport mechanism in an acoustic standing wave field.

PubMed

Xi, Xiaoyu; Cegla, Frederic B; Lowe, Michael; Thiemann, Andrea; Nowak, Till; Mettin, Robert; Holsteyns, Frank; Lippert, Alexander

2011-12-01

The use of bubbles in applications such as surface chemistry, drug delivery, and ultrasonic cleaning etc. has been enormously popular in the past two decades. It has been recognized that acoustically-driven bubbles can be used to disturb the flow field near a boundary in order to accelerate physical or chemical reactions on the surface. The interactions between bubbles and a surface have been studied experimentally and analytically. However, most of the investigations focused on violently oscillating bubbles (also known as cavitation bubble), less attention has been given to understand the interactions between moderately oscillating bubbles and a boundary. Moreover, cavitation bubbles were normally generated in situ by a high intensity laser beam, little experimental work has been carried out to study the translational trajectory of a moderately oscillating bubble in an acoustic field and subsequent interactions with the surface. This paper describes the design of an ultrasonic test cell and explores the mechanism of bubble manipulation within the test cell. The test cell consists of a transducer, a liquid medium and a glass backing plate. The acoustic field within the multi-layered stack was designed in such a way that it was effectively one dimensional. This was then successfully simulated by a one dimensional network model. The model can accurately predict the impedance of the test cell as well as the mode shape (distribution of particle velocity and stress/pressure field) within the whole assembly. The mode shape of the stack was designed so that bubbles can be pushed from their injection point onto a backing glass plate. Bubble radial oscillation was simulated by a modified Keller-Miksis equation and bubble translational motion was derived from an equation obtained by applying Newton's second law to a bubble in a liquid medium. Results indicated that the bubble trajectory depends on the acoustic pressure amplitude and initial bubble size: an increase of pressure amplitude or a decrease of bubble size forces bubbles larger than their resonant size to arrive at the target plate at lower heights, while the trajectories of smaller bubbles are less influenced by these factors. The test cell is also suitable for testing the effects of drag force on the bubble motion and for studying the bubble behavior near a surface. Copyright © 2011 Elsevier B.V. All rights reserved.

Charge Analyzer Responsive Local Oscillations

NASA Technical Reports Server (NTRS)

Krause, Linda Habash; Thornton, Gary

2015-01-01

The first transatlantic radio transmission, demonstrated by Marconi in December of 1901, revealed the essential role of the ionosphere for radio communications. This ionized layer of the upper atmosphere controls the amount of radio power transmitted through, reflected off of, and absorbed by the atmospheric medium. Low-frequency radio signals can propagate long distances around the globe via repeated reflections off of the ionosphere and the Earth's surface. Higher frequency radio signals can punch through the ionosphere to be received at orbiting satellites. However, any turbulence in the ionosphere can distort these signals, compromising the performance or even availability of space-based communication and navigations systems. The physics associated with this distortion effect is analogous to the situation when underwater images are distorted by convecting air bubbles. In fact, these ionospheric features are often called 'plasma bubbles' since they exhibit some of the similar behavior as underwater air bubbles. These events, instigated by solar and geomagnetic storms, can cause communication and navigation outages that last for hours. To help understand and predict these outages, a world-wide community of space scientists and technologists are devoted to researching this topic. One aspect of this research is to develop instruments capable of measuring the ionospheric plasma bubbles. Figure 1 shows a photo of the Charge Analyzer Responsive to Local Oscillations (CARLO), a new instrument under development at NASA Marshall Space Flight Center (MSFC). It is a frequency-domain ion spectrum analyzer designed to measure the distributions of ionospheric turbulence from 1 Hz to 10 kHz (i.e., spatial scales from a few kilometers down to a few centimeters). This frequency range is important since it focuses on turbulence scales that affect VHF/UHF satellite communications, GPS systems, and over-the-horizon radar systems. CARLO is based on the flight-proven Plasma Local Anomalous Noise Environment (PLANE) instrument, previously flown on a U.S. Air Force low-Earth orbiting satellite, which successfully measured ion turbulence in five frequency decades from 0.1 Hz to 10 kHz (fig 2).

Shape and evolution of wind-blown bubbles of massive stars: on the effect of the interstellar magnetic field

NASA Astrophysics Data System (ADS)

van Marle, A. J.; Meliani, Z.; Marcowith, A.

2015-12-01

Context. The winds of massive stars create large (>10 pc) bubbles around their progenitors. As these bubbles expand they encounter the interstellar coherent magnetic field which, depending on its strength, can influence the shape of the bubble. Aims: We wish to investigate if, and how much, the interstellar magnetic field can contribute to the shape of an expanding circumstellar bubble around a massive star. Methods: We use the MPI-AMRVAC code to make magneto-hydrodynamical simulations of bubbles, using a single star model, combined with several different field strengths: B = 5, 10, and 20 μG for the interstellar magnetic field. This covers the typical field strengths of the interstellar magnetic fields found in the galactic disk and bulge. Furthermore, we present two simulations that include both a 5 μG interstellar magnetic field and a warm (10 000 K) interstellar medium (ISM) and two different ISM densities to demonstrate how the magnetic field can combine with other external factors to influence the morphology of the circumstellar bubbles. Results: Our results show that low magnetic fields, as found in the galactic disk, inhibit the growth of the circumstellar bubbles in the direction perpendicular to the field. As a result, the bubbles become ovoid, rather than spherical. Strong interstellar fields, such as observed for the galactic bulge, can completely stop the expansion of the bubble in the direction perpendicular to the field, leading to the formation of a tube-like bubble. When combined with an ISM that is both warm and high density the bubble is greatly reduced in size, causing a dramatic change in the evolution of temporary features inside the bubble such as Wolf-Rayet ring nebulae. Conclusions: The magnetic field of the interstellar medium can affect the shape of circumstellar bubbles. This effect may have consequences for the shape and evolution of circumstellar nebulae and supernova remnants, which are formed within the main wind-blown bubble. Appendices and movies associated to Figs. A.1-A.12 are available in electronic form at http://www.aanda.org

Interface stability in a slowly rotating low-gravity tank Theory

NASA Technical Reports Server (NTRS)

Gans, R. F.; Leslie, F. W.

1986-01-01

The equilibrium configuration of a bubble in a rotating liquid confined by flat axial boundaries (baffles) is found. The maximum baffle spacing assuring bubble confinement is bounded from above by the natural length of a bubble in an infinite medium under the same conditions. Effects of nonzero contact angle are minimal. The problem of dynamic stability is posed. It can be solved in the limit of rapid rotation, for which the bubble is a long cylinder. Instability is to axisymmetric perturbations; nonaxisymmetric perturbations are stable. The stability criterion agrees with earlier results.

Bubble clustering in a glass of stout beer

NASA Astrophysics Data System (ADS)

Iwatsubo, Fumiya; Watamura, Tomoaki; Sugiyama, Kazuyasu

2017-11-01

To clarify why the texture in stout beer poured into a pint glass descends, we investigated local time development of the void fraction and velocity of bubbles. The propagation of the number density distribution, i.e. the texture, appearing near the inclined wall is observed. We visualized individual advective bubbles near the inclined wall by microscope and measured the local void fraction using brightness of images while the velocity of bubbles by means of Particle Tracking Velocimetry. As the result of measurements, we found the local void fraction and the bubbles advection velocity increase and decrease repeatedly with a time delay. We conclude the texture pattern is composed of fluid blobs which contain less bubbles; extruding and suction flows respectively toward and from the interior of the container form respectively in front and back of the blobs.

Foam flow in a model porous medium: II. The effect of trapped gas.

PubMed

Jones, S A; Getrouw, N; Vincent-Bonnieu, S

2018-05-09

Gas trapping is an important mechanism in both Water or Surfactant Alternating Gas (WAG/SAG) and foam injection processes in porous media. Foams for enhanced oil recovery (EOR) can increase sweep efficiency as they decrease the gas relative permeability, and this is mainly due to gas trapping. However, gas trapping mechanisms are poorly understood. Some studies have been performed during corefloods, but little work has been carried out to describe the bubble trapping behaviour at the pore scale. We have carried out foam flow tests in a micromodel etched with an irregular hexagonal pattern. Image analysis of the foam flow allowed the bubble centres to be tracked and local velocities to be obtained. It was found that the flow in the micromodel is dominated by intermittency and localized zones of trapped gas. The quantity of trapped gas was measured both by considering the fraction of bubbles that were trapped (via velocity thresholding) and by measuring the area fraction containing immobile gas (via image analysis). A decrease in the quantity of trapped gas was observed for both increasing total velocity and increasing foam quality. Calculations of the gas relative permeability were made with the Brooks Corey equation, using the measured trapped gas saturations. The results showed a decrease in gas relative permeabilities, and gas mobility, for increasing fractions of trapped gas. It is suggested that the shear thinning behaviour of foam could be coupled to the saturation of trapped gas.

Revising the Local Bubble Model due to Solar Wind Charge Exchange X-ray Emission

NASA Astrophysics Data System (ADS)

Shelton, Robin L.

2009-03-01

The hot Local Bubble surrounding the solar neighborhood has been primarily studied through observations of its soft X-ray emission. The measurements were obtained by attributing all of the observed local soft X-rays to the bubble. However, mounting evidence shows that the heliosphere also produces diffuse X-rays. The source is solar wind ions that have received an electron from another atom. The presence of this alternate explanation for locally produced diffuse X-rays calls into question the existence and character of the Local Bubble. This article addresses these questions. It reviews the literature on solar wind charge exchange (SWCX) X-ray production, finding that SWCX accounts for roughly half of the observed local 1/4 keV X-rays found at low latitudes. This article also makes predictions for the heliospheric O VI column density and intensity, finding them to be smaller than the observational error bars. Evidence for the continued belief that the Local Bubble contains hot gas includes the remaining local 1/4 keV intensity, the observed local O VI column density, and the need to fill the local region with some sort of plasma. If the true Local Bubble is half as bright as previously thought, then its electron density and thermal pressure are 1/sqrt{2} as great as previously thought, and its energy requirements and emission measure are 1/2 as great as previously thought. These adjustments can be accommodated easily, and, in fact, bring the Local Bubble’s pressure more in line with that of the adjacent material. Suggestions for future work are made.

Reversible switch between underwater superaerophilicity and superaerophobicity on the superhydrophobic nanowire-haired mesh for controlling underwater bubble wettability

NASA Astrophysics Data System (ADS)

Shan, Chao; Yong, Jiale; Yang, Qing; Chen, Feng; Huo, Jinglan; Zhuang, Jian; Jiang, Zhuangde; Hou, Xun

2018-04-01

Controlling the underwater bubble wettability on a solid surface is of great research significance. In this letter, a simple method to achieve reversible switch between underwater superaerophilicity and underwater superaerophobicity on a superhydrophobic nanowire-haired mesh by alternately vacuumizing treatment in water and drying in air is reported. Such reversible switch endows the as-prepared mesh with many functional applications in controlling bubble's behavior on a solid substrate. The underwater superaerophilic mesh is able to absorb/capture bubbles in water, while the superaerophobic mesh has great anti-bubble ability. The reversible switch between underwater superaerophilicity and superaerophobicity can selectively allow bubbles to go through the resultant mesh; that is, bubbles can pass through the underwater superaerophilic mesh while are fully intercepted by the underwater superaerophobic mesh in a water medium. We believe these meshes will have important applications in removing or capturing underwater bubbles/gas.

Bubble technique for Descemet membrane endothelial keratoplasty tissue preparation in an eye bank: air or liquid?

PubMed

Ruzza, Alessandro; Parekh, Mohit; Salvalaio, Gianni; Ferrari, Stefano; Camposampiero, Davide; Amoureux, Marie-Claude; Busin, Massimo; Ponzin, Diego

2015-03-01

To compare the big-bubble method using air and liquid as medium of separation for Descemet membrane endothelial keratoplasty (DMEK) lenticule preparation in an eye bank. Donor corneas (n=20) were immersed in liquid [tissue culture medium (TCM)]. Air and liquid was injected using a 25-gauge needle in the posterior stroma or as near to the stroma-Descemet membrane (DM) phase as possible to create a complete bubble of larger diameter. The endothelial cell density and mortality were checked pre- and postbubble after deflating the tissue. Four pairs of tissues were used to analyse the intracellular tight junctions and three pairs for histological examination and DNA integrity studies, respectively. The yield obtained using air was 80%, whereas that with liquid was 100%. Single injection was required in six cases; twice in two cases; three and four times in one case each with air bubble, whereas seven cases required single injection; twice in two cases; and thrice in just one case with liquid bubble. The average diameter of the final lenticule was 9.12 (±1.71) mm for air bubble and 9.78 (±1.75) mm for liquid bubble with p=0.4362 (no statistical significance). Endothelial cell mortality postbubble preparation was 8.9 (±12.38)% for air and 6.25 (±9.57)% for liquid (p=0.6268). DM and endothelium could be separated exclusively using air or liquid bubble. However, liquid bubble seems to have certain advantages over air such as the generation of yield, larger diameter and higher maintenance of endothelial cell density and integrity. © 2014 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

Investigation of multilayer magnetic domain lattice file

NASA Technical Reports Server (NTRS)

Torok, E. J.; Kamin, M.; Tolman, C. H.

1980-01-01

The feasibility of the self structured multilayered bubble domain memory as a mass memory medium for satellite applications is examined. Theoretical considerations of multilayer bubble supporting materials are presented, in addition to the experimental evaluation of current accessed circuitry for various memory functions. The design, fabrication, and test of four device designs is described, and a recommended memory storage area configuration is presented. Memory functions which were demonstrated include the current accessed propagation of bubble domains and stripe domains, pinning of stripe domain ends, generation of single and double bubbles, generation of arrays of coexisting strip and bubble domains in a single garnet layer, and demonstration of different values of the strip out field for single and double bubbles indicating adequate margins for data detection. All functions necessary to develop a multilayer self structured bubble memory device were demonstrated in individual experiments.

Generation of Internal Waves by Buoyant Bubbles in Galaxy Clusters and Heating of Intracluster Medium

NASA Astrophysics Data System (ADS)

Zhang, Congyao; Churazov, Eugene; Schekochihin, Alexander A.

2018-05-01

Buoyant bubbles of relativistic plasma in cluster cores plausibly play a key role in conveying the energy from a supermassive black hole to the intracluster medium (ICM) - the process known as radio-mode AGN feedback. Energy conservation guarantees that a bubble loses most of its energy to the ICM after crossing several pressure scale heights. However, actual processes responsible for transferring the energy to the ICM are still being debated. One attractive possibility is the excitation of internal waves, which are trapped in the cluster's core and eventually dissipate. Here we show that a sufficient condition for efficient excitation of these waves in stratified cluster atmospheres is flattening of the bubbles in the radial direction. In our numerical simulations, we model the bubbles phenomenologically as rigid bodies buoyantly rising in the stratified cluster atmosphere. We find that the terminal velocities of the flattened bubbles are small enough so that the Froude number Fr ≲ 1. The effects of stratification make the dominant contribution to the total drag force balancing the buoyancy force. Clear signs of internal waves are seen in the simulations. These waves propagate horizontally and downwards from the rising bubble, spreading their energy over large volumes of the ICM. If our findings are scaled to the conditions of the Perseus cluster, the expected terminal velocity is ˜100 - 200 km s-1 near the cluster cores, which is in broad agreement with direct measurements by the Hitomi satellite.

Formation of bubbly horizon in liquid-saturated porous medium by surface temperature oscillation.

PubMed

Goldobin, Denis S; Krauzin, Pavel V

2015-12-01

We study nonisothermal diffusion transport of a weakly soluble substance in a liquid-saturated porous medium in contact with a reservoir of this substance. The surface temperature of the porous medium half-space oscillates in time, which results in a decaying solubility wave propagating deep into the porous medium. In this system, zones of saturated solution and nondissolved phase coexist with ones of undersaturated solution. The effect is first considered for the case of annual oscillation of the surface temperature of water-saturated ground in contact with the atmosphere. We reveal the phenomenon of formation of a near-surface bubbly horizon due to temperature oscillation. An analytical theory of the phenomenon is developed. Further, the treatment is extended to the case of higher frequency oscillations and the case of weakly soluble solids and liquids.

Research on acting mechanism and behavior of a gas bubble in the air dense medium fluidized bed

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tao, X.; Chen, Q.; Yang, Y.

1996-12-31

Coal dry beneficiation with air-dense medium fluidized bed has now been established as a high efficiency dry separation technology, it is the application of fluidization technology to the coal preparation field. The tiny particle media forms an uniform and stable fluidized bed with a density acted by airflow, which is used to separate 80{micro}m to {approximately}6mm size coal. This technology has achieved satisfied industrialization results, and attracted the expert`s attention in the field. In fluidized bed, the interaction between gas and solid was mainly decided by the existence state of heavy media particles mass (position and distance) relative velocity ofmore » gas-solid two phase, as well turbulent action. A change of vertical gas-solid fluidizing state essentially is the one of a energy transforming process. For a coal separating process with air-dense medium fluidized bed, the gas bubble, producing a turbulent and stirring action in the bed, leads to two effects. It can promote a uniform distribution of heavy media particles, and a uniform and stability of a bed density. Otherwise it will decrease effective contacts between gas-solids two phases, producing a bigger gas bubble. Therefore controlling a gas bubble size in bed should be optimized. This paper analyzes mutual movement between gas-solid, and studies the gas bubble behavior in the bed. A mechanic mode and a separating process of coal in the bed is discussed. It aims to research the coal separating mechanism with air-dense fluidized bed.« less

Two-Dimensional Numerical Simulations of Ultrasound in Liquids with Gas Bubble Agglomerates: Examples of Bubbly-Liquid-Type Acoustic Metamaterials (BLAMMs)

PubMed Central

Vanhille, Christian

2017-01-01

This work deals with a theoretical analysis about the possibility of using linear and nonlinear acoustic properties to modify ultrasound by adding gas bubbles of determined sizes in a liquid. We use a two-dimensional numerical model to evaluate the effect that one and several monodisperse bubble populations confined in restricted areas of a liquid have on ultrasound by calculating their nonlinear interaction. The filtering of an input ultrasonic pulse performed by a net of bubbly-liquid cells is analyzed. The generation of a low-frequency component from a single cell impinged by a two-frequency harmonic wave is also studied. These effects rely on the particular dispersive character of attenuation and nonlinearity of such bubbly fluids, which can be extremely high near bubble resonance. They allow us to observe how gas bubbles can change acoustic signals. Variations of the bubbly medium parameters induce alterations of the effects undergone by ultrasound. Results suggest that acoustic signals can be manipulated by bubbles. This capacity to achieve the modification and control of sound with oscillating gas bubbles introduces the concept of bubbly-liquid-based acoustic metamaterials (BLAMMs). PMID:28106748

Two-Dimensional Numerical Simulations of Ultrasound in Liquids with Gas Bubble Agglomerates: Examples of Bubbly-Liquid-Type Acoustic Metamaterials (BLAMMs).

PubMed

Vanhille, Christian

2017-01-17

This work deals with a theoretical analysis about the possibility of using linear and nonlinear acoustic properties to modify ultrasound by adding gas bubbles of determined sizes in a liquid. We use a two-dimensional numerical model to evaluate the effect that one and several monodisperse bubble populations confined in restricted areas of a liquid have on ultrasound by calculating their nonlinear interaction. The filtering of an input ultrasonic pulse performed by a net of bubbly-liquid cells is analyzed. The generation of a low-frequency component from a single cell impinged by a two-frequency harmonic wave is also studied. These effects rely on the particular dispersive character of attenuation and nonlinearity of such bubbly fluids, which can be extremely high near bubble resonance. They allow us to observe how gas bubbles can change acoustic signals. Variations of the bubbly medium parameters induce alterations of the effects undergone by ultrasound. Results suggest that acoustic signals can be manipulated by bubbles. This capacity to achieve the modification and control of sound with oscillating gas bubbles introduces the concept of bubbly-liquid-based acoustic metamaterials (BLAMMs).

Self-organization of cosmic radiation pressure instability. II - One-dimensional simulations

NASA Technical Reports Server (NTRS)

Hogan, Craig J.; Woods, Jorden

1992-01-01

The clustering of statistically uniform discrete absorbing particles moving solely under the influence of radiation pressure from uniformly distributed emitters is studied in a simple one-dimensional model. Radiation pressure tends to amplify statistical clustering in the absorbers; the absorbing material is swept into empty bubbles, the biggest bubbles grow bigger almost as they would in a uniform medium, and the smaller ones get crushed and disappear. Numerical simulations of a one-dimensional system are used to support the conjecture that the system is self-organizing. Simple statistics indicate that a wide range of initial conditions produce structure approaching the same self-similar statistical distribution, whose scaling properties follow those of the attractor solution for an isolated bubble. The importance of the process for large-scale structuring of the interstellar medium is briefly discussed.

Synchrotron x-ray imaging of acoustic cavitation bubbles induced by acoustic excitation

NASA Astrophysics Data System (ADS)

Jung, Sung Yong; Park, Han Wook; Park, Sung Ho; Lee, Sang Joon

2017-04-01

The cavitation induced by acoustic excitation has been widely applied in various biomedical applications because cavitation bubbles can enhance the exchanges of mass and energy. In order to minimize the hazardous effects of the induced cavitation, it is essential to understand the spatial distribution of cavitation bubbles. The spatial distribution of cavitation bubbles visualized by the synchrotron x-ray imaging technique is compared to that obtained with a conventional x-ray tube. Cavitation bubbles with high density in the region close to the tip of the probe are visualized using the synchrotron x-ray imaging technique, however, the spatial distribution of cavitation bubbles in the whole ultrasound field is not detected. In this study, the effects of the ultrasound power of acoustic excitation and working medium on the shape and density of the induced cavitation bubbles are examined. As a result, the synchrotron x-ray imaging technique is useful for visualizing spatial distributions of cavitation bubbles, and it could be used for optimizing the operation conditions of acoustic cavitation.

Shock-Bubble Heating of the Intracluster Medium

NASA Astrophysics Data System (ADS)

Friedman, Samuel H.; Heinz, S.; Churazov, E.

2011-01-01

Active galactic nuclei (AGN) Feedback via extragalactic jets requires a thermalization of the energy injected into the intracluster medium (ICM) in order for energy feedback to occur. Heinz and Churazov (2005) proposed a method using shock waves and previously inflated bubbles in the ICM to extract energy from the shock waves and turn the energy into rotational kinetic energy. This energy would decay and allow heating to occur elsewhere throughout the galaxy cluster. In this paper, we extend to three dimensions (3D) the previous work using hydrodynamic simulations. We also compare our results to previous related work done performed experimentally.

Electromagnetically actuated micromanipulator using an acoustically oscillating bubble

NASA Astrophysics Data System (ADS)

Kwon, J. O.; Yang, J. S.; Lee, S. J.; Rhee, K.; Chung, S. K.

2011-11-01

A novel non-invasive micromanipulation technique has been developed where a microrobot swimming in an aqueous medium manipulates micro-objects, through electromagnetic actuation using an acoustically oscillating bubble attached to the microrobot as a grasping tool. This micromanipulation concept was experimentally verified; an investigation of electromagnetic actuation and acoustic excitation was also performed. Two-dimensional propulsion of a magnetic piece was demonstrated through electromagnetic actuation, using three pairs of electric coils surrounding the water chamber, and confirming that the propulsion speed of the magnetic piece was linearly proportional to the applied current intensity. Micro-object manipulation was separately demonstrated using an air bubble with glass beads (80 µm diameter) and a steel ball (800 µm diameter) in an aqueous medium. Upon acoustic excitation of the bubble by a piezo-actuator around its resonant frequency, the generated radiation force attracted and captured the neighboring glass beads and steel ball. The grasping force was indirectly measured by exposing the glass beads captured by the oscillating bubble to a stream generated by an auto-syringe pump in a mini-channel. By measuring the maximum speed of the streaming flow when the glass beads detached from the oscillating bubble and flowed downstream, the grasping force was calculated as 50 nN, based on Stokes' drag approximation. Finally, a fish egg was successfully manipulated with the integration of electromagnetic actuation and acoustic excitation, using a mini-robot consisting of a millimeter-sized magnetic piece with a bubble attached to its bottom. This novel micromanipulation may be an efficient tool for both micro device assembly and single-cell manipulation.

The rheology of three-phase suspensions at low bubble capillary number

PubMed Central

Truby, J. M.; Mueller, S. P.; Llewellin, E. W.; Mader, H. M.

2015-01-01

We develop a model for the rheology of a three-phase suspension of bubbles and particles in a Newtonian liquid undergoing steady flow. We adopt an ‘effective-medium’ approach in which the bubbly liquid is treated as a continuous medium which suspends the particles. The resulting three-phase model combines separate two-phase models for bubble suspension rheology and particle suspension rheology, which are taken from the literature. The model is validated against new experimental data for three-phase suspensions of bubbles and spherical particles, collected in the low bubble capillary number regime. Good agreement is found across the experimental range of particle volume fraction (0≤ϕp≲0.5) and bubble volume fraction (0≤ϕb≲0.3). Consistent with model predictions, experimental results demonstrate that adding bubbles to a dilute particle suspension at low capillarity increases its viscosity, while adding bubbles to a concentrated particle suspension decreases its viscosity. The model accounts for particle anisometry and is easily extended to account for variable capillarity, but has not been experimentally validated for these cases. PMID:25568617

Characteristics of plasma in culture medium generated by positive pulse voltage and effects of organic compounds on its characteristics

NASA Astrophysics Data System (ADS)

Sato, Y.; Sato, T.; Yoshino, D.

2016-12-01

We describe a positive pulse voltage method for generating plasma in culture medium with a composition similar to biological fluids. We also describe the plasma’s characteristics, liquid quality, and the effect of organic compounds in the culture medium on the plasma characteristics through comparisons to a solution containing inorganic salts at the same concentrations as in the culture medium. Light emission with Na and OH spectra was observed within a vapor bubble produced by Joule heating at the tip of the electrode. A downward thermal flow and shock wave were caused by the behavior of the vapor bubble. The culture medium pH gradually increased from 7.9 to 8.3 over the discharge time of 300 s. H2O2 was generated 1.1 mg l-1 in the culture medium after discharge for 300 s, and this value was 0.5 mg l-1 lower than the inorganic salts solution which does not contain organic compounds. This study provides important data that will help facilitate more widespread application of plasma medicine.

Occlusion and rupture of ex vivo capillary bifurcation due to acoustic droplet vaporization

NASA Astrophysics Data System (ADS)

Feng, Yi; Qin, Dui; Zhang, Jun; Zhang, Lei; Bouakaz, Ayache; Wan, Mingxi

2018-06-01

Gas embolotherapy (GE) consists in the occlusion of tumor blood vessels using gas emboli induced by acoustic droplet vaporization (ADV), to create tumor starvation and localized drug delivery. Therefore, the occlusion and rupture of capillary bifurcation due to ADV was investigated in an ex vivo rat mesentery model using a confocal acousto-optical high-speed microscope system. Following ADV bubble formation, coalescence, and translational movement, the growing bubbles lodged in and then occluded two different capillary bifurcations. Capillary rupture was induced at the bubble lodging area, immediately followed by gas extravasation and bubble dislodging. Before and after bubble lodgment/occlusion, a local microvessel invagination was observed due to the interactions between ADV bubbles and the microvessel itself, indicating a contribution to the capillary rupture. Understanding the transient dynamics of ADV bubble, the bubble-microvessel interaction and the consequent mechanical bio-effects in GE is of the paramount importance for developing and applying this approach in clinical practice.

Supernova remnant evolution in wind bubbles: A closer look at Kes 27

NASA Astrophysics Data System (ADS)

Dwarkadas, V. V.; Dewey, D.

2013-03-01

Massive Stars (>8M⊙) lose mass in the form of strong winds. These winds accumulate around the star, forming wind-blown bubbles. When the star explodes as a supernova (SN), the resulting shock wave expands within this wind-blown bubble, rather than the interstellar medium. The properties of the resulting remnant, its dynamics and kinematics, the morphology, and the resulting evolution, are shaped by the structure and properties of the wind-blown bubble. In this article we focus on Kes 27, a supernova remnant (SNR) that has been proposed by [1] to be evolving in a wind-blown bubble, explore its properties, and investigate whether the X-Ray properties could be ascribed to evolution of a SNR in a wind-blown bubble. Our initial model does not support the scenario proposed by [1], due to the fact that the reflected shock is expanding into much lower densities.

Emulsions Containing Perfluorocarbon Support Cell Cultures

NASA Technical Reports Server (NTRS)

Ju, Lu-Kwang; Lee, Jaw Fang; Armiger, William B.

1990-01-01

Addition of emulsion containing perfluorocarbon liquid to aqueous cell-culture medium increases capacity of medium to support mammalian cells. FC-40 Fluorinert (or equivalent) - increases average density of medium so approximately equal to that of cells. Cells stay suspended in medium without mechanical stirring, which damages them. Increases density enough to prevent cells from setting, and increases viscosity of medium so oxygen bubbled through it and nutrients stirred in with less damage to delicate cells.

The dynamics of histotripsy bubbles

NASA Astrophysics Data System (ADS)

Kreider, Wayne; Bailey, Michael R.; Sapozhnikov, Oleg A.; Khokhlova, Vera A.; Crum, Lawrence A.

2011-09-01

Histotripsy describes treatments in which high-amplitude acoustic pulses are used to excite bubbles and erode tissue. Though tissue erosion can be directly attributed to bubble activity, the genesis and dynamics of bubbles remain unclear. Histotripsy lesions that show no signs of thermal coagulative damage have been generated with two different acoustic protocols: relatively long acoustic pulses that produce local boiling within milliseconds and relatively short pulses that are higher in amplitude but likely do not produce boiling. While these two approaches are often distinguished as `boiling' versus `cavitation', such labels can obscure similarities. In both cases, a bubble undergoes large changes in radius and vapor is transported into and out of the bubble as it oscillates. Moreover, observations from both approaches suggest that bubbles grow to a size at which they cease to collapse violently. In order to better understand the dynamics of histotripsy bubbles, a single-bubble model has been developed that couples acoustically excited bubble motions to the thermodynamic state of the surrounding liquid. Using this model for bubbles exposed to histotripsy sound fields, simulations suggest that two mechanisms can act separately or in concert to lead to the typically observed bubble growth. First, nonlinear acoustic propagation leads to the evolution of shocks and an asymmetry in the positive and negative pressures that drive bubble motion. This asymmetry can have a rectifying effect on bubble oscillations whereby the bubble grows on average during each acoustic cycle. Second, vapor transport to/from the bubble tends to produce larger bubbles, especially at elevated temperatures. Vapor transport by itself can lead to rectified bubble growth when the ambient temperature exceeds 100 °C (`boiling') or local heating in the vicinity of the bubble leads to a superheated boundary layer.

PROBING THE LOCAL BUBBLE WITH DIFFUSE INTERSTELLAR BANDS. II. THE DIB PROPERTIES IN THE NORTHERN HEMISPHERE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farhang, Amin; Khosroshahi, Habib G.; Javadi, Atefeh

2015-02-10

We present a new high signal-to-noise ratio spectroscopic survey of the Northern hemisphere to probe the Local Bubble and its surroundings using the λ5780 Å and λ5797 Å diffuse interstellar bands (DIBs). We observed 432 sightlines to a distance of 200 pc over a duration of three years. In this study, we establish the λ5780 and λ5797 correlations with Na I, Ca II and E {sub B-V}, for both inside and outside the Local Bubble. The correlations show that among all neutral and ionized atoms, the correlation between Ca II and λ5780 is stronger than its correlation with λ5797, suggestingmore » that λ5780 is more associated with regions where Ca{sup +} is more abundant. We study the λ5780 correlation with λ5797, which shows a tight correlation within and outside the Local Bubble. In addition, we investigate the DIB properties in UV irradiated and UV shielded regions. We find that, within and beyond the Local Bubble, λ5797 is located in denser parts of clouds, protected from UV irradiation, while λ5780 is located in the low-density regions of clouds.« less

Application of time-resolved shadowgraph imaging and computer analysis to study micrometer-scale response of superfluid helium

NASA Astrophysics Data System (ADS)

Sajjadi, Seyed; Buelna, Xavier; Eloranta, Jussi

2018-01-01

Application of inexpensive light emitting diodes as backlight sources for time-resolved shadowgraph imaging is demonstrated. The two light sources tested are able to produce light pulse sequences in the nanosecond and microsecond time regimes. After determining their time response characteristics, the diodes were applied to study the gas bubble formation around laser-heated copper nanoparticles in superfluid helium at 1.7 K and to determine the local cavitation bubble dynamics around fast moving metal micro-particles in the liquid. A convolutional neural network algorithm for analyzing the shadowgraph images by a computer is presented and the method is validated against the results from manual image analysis. The second application employed the red-green-blue light emitting diode source that produces light pulse sequences of the individual colors such that three separate shadowgraph frames can be recorded onto the color pixels of a charge-coupled device camera. Such an image sequence can be used to determine the moving object geometry, local velocity, and acceleration/deceleration. These data can be used to calculate, for example, the instantaneous Reynolds number for the liquid flow around the particle. Although specifically demonstrated for superfluid helium, the technique can be used to study the dynamic response of any medium that exhibits spatial variations in the index of refraction.

Thermodynamic and kinetic considerations of nucleation and stabilization of acoustic cavitation bubbles in water.

PubMed

Bapat, Pratap S; Pandit, Aniruddha B

2008-01-01

Qualitative explanation for a homogeneous nucleation of acoustic cavitation bubbles in the incompressible liquid water with simple phenomenological approach has been provided via the concept of the desorbtion of the dissolved gas and the vaporization of local liquid molecules. The liquid medium has been viewed as an ensemble of lattice structures. Validity of the lattice structure approach against the Brownian motion of molecules in the liquid state has been discussed. Criterion based on probability for nucleus formation has been defined for the vaporization of local liquid molecules. Energy need for the enthalpy of vaporization has been considered as an energy criterion for the formation of a vaporous nucleus. Sound energy, thermal energy of the liquid bulk (Joule-Thomson effect) and free energy of activation, which is associated with water molecules in the liquid state (Brownian motion) as per the modified Eyring's kinetic theory of liquid are considered as possible sources for the enthalpy of vaporization of water molecules forming a single unit lattice. The classical nucleation theory has then been considered for expressing further growth of the vaporous nucleus against the surface energy barrier. Effect of liquid property (temperature), and effect of an acoustic parameter (frequency) on an acoustic cavitation threshold pressure have been discussed. Kinetics of nucleation has been considered.

Ray-based acoustic localization of cavitation in a highly reverberant environment.

PubMed

Chang, Natasha A; Dowling, David R

2009-05-01

Acoustic detection and localization of cavitation have inherent advantages over optical techniques because cavitation bubbles are natural sound sources, and acoustic transduction of cavitation sounds does not require optical access to the region of cavitating flow. In particular, near cavitation inception, cavitation bubbles may be visually small and occur infrequently, but may still emit audible sound pulses. In this investigation, direct-path acoustic recordings of cavitation events are made with 16 hydrophones mounted on the periphery of a water tunnel test section containing a low-cavitation-event-rate vortical flow. These recordings are used to localize the events in three dimensions via cross correlations to obtain arrival time differences. Here, bubble localization is hindered by reverberation, background noise, and the fact that both the pulse emission time and waveform are unknown. These hindrances are partially mitigated by a signal-processing scheme that incorporates straight-ray acoustic propagation and Monte-Carlo techniques for compensating ray-path, sound-speed, and hydrophone-location uncertainties. The acoustic localization results are compared to simultaneous optical localization results from dual-camera high-speed digital-video recordings. For 53 bubbles and a peak-signal to noise ratio frequency of 6.7 kHz, the root-mean-square spatial difference between optical and acoustic bubble location results was 1.94 cm. Parametric dependences in acoustic localization performance are also presented.

Wind bubbles within H ii regions around slowly moving stars

NASA Astrophysics Data System (ADS)

Mackey, Jonathan; Gvaramadze, Vasilii V.; Mohamed, Shazrene; Langer, Norbert

2015-01-01

Interstellar bubbles around O stars are driven by a combination of the star's wind and ionizing radiation output. The wind contribution is uncertain because the boundary between the wind and interstellar medium is difficult to observe. Mid-infrared observations (e.g., of the H ii region RCW 120) show arcs of dust emission around O stars, contained well within the H ii region bubble. These arcs could indicate the edge of an asymmetric stellar wind bubble, distorted by density gradients and/or stellar motion. We present two-dimensional, radiation-hydrodynamics simulations investigating the evolution of wind bubbles and H ii regions around massive stars moving through a dense (nH = 3000 cm-3), uniform medium with velocities ranging from 4 to 16 km s-1. The H ii region morphology is strongly affected by stellar motion, as expected, but the wind bubble is also very aspherical from birth, even for the lowest space velocity considered. Wind bubbles do not fill their H ii regions (we find filling factors of 10-20 per cent), at least for a main sequence star with mass M⋆ ~ 30 M⊙. Furthermore, even for supersonic velocities the wind bow shock does not significantly trap the ionization front. X-ray emission from the wind bubble is soft, faint, and comes mainly from the turbulent mixing layer between the wind bubble and the H ii region. The wind bubble radiates <1 per cent of its energy in X-rays; it loses most of its energy by turbulent mixing with cooler photoionized gas. Comparison of the simulations with the H ii region RCW 120 shows that its dynamical age is ≲0.4 Myr and that stellar motion ≲4 km s-1 is allowed, implying that the ionizing source is unlikely to be a runaway star but more likely formed in situ. The region's youth, and apparent isolation from other O or B stars, makes it very interesting for studies of massive star formation and of initial mass functions. Movies are available in electronic form at http://www.aanda.org

Dynamics of Ultrasound Contrast Agents and Nonlinear Acoustic Waves: Experiments, Modeling, and Theories

NASA Astrophysics Data System (ADS)

Xia, Lang

Bubbles occur in many natural and biological flows as well as in numerous industrial phenomena, such as pumps, propellers, turbines, and chemical processing plants. They have been widely studied in the past leading to a large body of literature. However, bubbles appearing in different situations differ significantly in their physical characteristics and behaviors. Recently, bubbles of diameter less than 10 micrometers have found applications in diagnostic ultrasound imaging. These microbubble-based ultrasound contrast agents (UCA) are intravenously administered in patients before ultrasound imaging. Due to the compressive gas core, they generate substantial ultrasound echoes leading to significant enhancement of image quality and contrast. Free bubbles of a micrometer diameter experience a large surface tension induced Laplace pressure leading to their quick dissolution in milliseconds. UCAs are stabilized by coating them with a shell of lipids, polymers, proteins, and other surface-active materials and changing the gas content from air to a high molecular weight low solubility gas such as perfluorocarbon. The past literature of bubble dynamics are mostly restricted to free bubbles. The stabilizing shell of UCAs, however, critically affects their dynamics. In this thesis, we performed acoustic characterization of several UCAs coated with polymer and lipids. We experimentally measured their acoustic attenuation and scattering, of which the data were used in mathematical models to determine shell properties and nonlinear dynamics. Several different interfacial rheological models were employed. Experimental acoustic characterization was also extended to a novel type of nanoparticle suspension--polymersomes, vesicles encapsulated by amphiphilic polymers. The later part of the thesis is devoted to modeling the effects of the presence of coated microbubbles to the overall effective bulk properties of bubbly liquids. Introduction of microbubbles in the liquids does not only modify the bulk properties of the medium (bubbly liquids) but also significantly changes the natures of the propagating waves (e.g., the sound velocity in bubble suspension was found to be as low as 20 m/s). We investigate the nonlinear nature of the acoustic wave in bubbly liquids. Specifically, we theoretically show that microbubbles could change the nonlinearity of the medium, characterized by quantity B/A.

Acoustic Characterization of Fluorinert FC-43 Liquid with Helium Gas Bubbles: Numerical Experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vanhille, Christian; Pantea, Cristian; Sinha, Dipen N.

In this work, we define the acoustic characteristics of a biphasic fluid consisting of static helium gas bubbles in liquid Fluorinert FC-43 and study the propagation of ultrasound of finite amplitudes in this medium. Very low sound speed and high sound attenuation are found, in addition to a particularly high acoustic nonlinear parameter. This result suggests the possibility of using this medium as a nonlinear enhancer in various applications. In particular, parametric generation of low ultrasonic frequencies is studied in a resonator cavity as a function of driving pressure showing high conversion efficiency. This work suggests that this medium couldmore » be used for applications such as parametric arrays, nondestructive testing, diagnostic medicine, sonochemistry, underwater acoustics, and ultrasonic imaging and to boost the shock formation in fluids.« less

Acoustic Characterization of Fluorinert FC-43 Liquid with Helium Gas Bubbles: Numerical Experiments

DOE PAGES

Vanhille, Christian; Pantea, Cristian; Sinha, Dipen N.

2017-01-19

In this work, we define the acoustic characteristics of a biphasic fluid consisting of static helium gas bubbles in liquid Fluorinert FC-43 and study the propagation of ultrasound of finite amplitudes in this medium. Very low sound speed and high sound attenuation are found, in addition to a particularly high acoustic nonlinear parameter. This result suggests the possibility of using this medium as a nonlinear enhancer in various applications. In particular, parametric generation of low ultrasonic frequencies is studied in a resonator cavity as a function of driving pressure showing high conversion efficiency. This work suggests that this medium couldmore » be used for applications such as parametric arrays, nondestructive testing, diagnostic medicine, sonochemistry, underwater acoustics, and ultrasonic imaging and to boost the shock formation in fluids.« less

Oscillating microbubbles for selective particle sorting in acoustic microfluidic devices

NASA Astrophysics Data System (ADS)

Rogers, Priscilla; Xu, Lin; Neild, Adrian

2012-05-01

In this study, acoustic waves were used to excite a microbubble for selective particle trapping and sorting. Excitation of the bubble at its volume resonance, as necessary to drive strong fluid microstreaming, resulted in the particles being either selectively attracted to the bubble or continuing to follow the local microstreamlines. The operating principle exploited two acoustic phenomena acting on the particle suspension: the drag force arising from the acoustic microstreaming and the secondary Bjerknes force, i.e. the attractive radiation force produced between an oscillating bubble and a non-buoyant particle. It was also found that standing wave fields within the fluid chamber could be used to globally align bubbles and particles for local particle sorting by the bubble.

Localized removal of layers of metal, polymer, or biomaterial by ultrasound cavitation bubbles

PubMed Central

Fernandez Rivas, David; Verhaagen, Bram; Seddon, James R. T.; Zijlstra, Aaldert G.; Jiang, Lei-Meng; van der Sluis, Luc W. M.; Versluis, Michel; Lohse, Detlef; Gardeniers, Han J. G. E.

2012-01-01

We present an ultrasonic device with the ability to locally remove deposited layers from a glass slide in a controlled and rapid manner. The cleaning takes place as the result of cavitating bubbles near the deposited layers and not due to acoustic streaming. The bubbles are ejected from air-filled cavities micromachined in a silicon surface, which, when vibrated ultrasonically at a frequency of 200 kHz, generate a stream of bubbles that travel to the layer deposited on an opposing glass slide. Depending on the pressure amplitude, the bubble clouds ejected from the micropits attain different shapes as a result of complex bubble interaction forces, leading to distinct shapes of the cleaned areas. We have determined the removal rates for several inorganic and organic materials and obtained an improved efficiency in cleaning when compared to conventional cleaning equipment. We also provide values of the force the bubbles are able to exert on an atomic force microscope tip. PMID:23964308

Magnetic Field Strengths and Grain Alignment Variations in the Local Bubble Wall

NASA Astrophysics Data System (ADS)

Medan, Ilija; Andersson, B.-G.

2018-01-01

Optical and infrared continuum polarization is known to be due to irregular dust grains aligned with the magnetic field. This provides an important tool to probe the geometry and strength of those fields, particularly if the variations in the grain alignment efficiencies can be understood. Here, we examine polarization variations observed throughout the Local Bubble for b>30○, using a large polarization survey of the North Galactic cap from Berdyugin et al. (2014). These data are supported by archival photometric and spectroscopic data along with the mapping of the Local Bubble by Lallement et al. (2003). We can accurately model the observational data assuming that the grain alignment variations are due to the radiation from the OB associations within 1 kpc of the sun. This strongly supports radiatively driven grain alignment. We also probe the relative strength of the magnetic field in the wall of the Local Bubble using the Davis-Chandrasekhar-Fermi method. We find evidence for a bimodal field strength distribution, where the variations in the field are correlated with the variations in grain alignment efficiency, indicating that the higher strength regions might represent a compression of the wall by the interaction of the outflow in the Local Bubble and the opposing flows by the surrounding OB associations.

Collective bubble oscillations as a component of surf infrasound.

PubMed

Park, Joseph; Garcés, Milton; Fee, David; Pawlak, Geno

2008-05-01

Plunging surf is a known generator of infrasound, though the mechanisms have not been clearly identified. A model based on collective bubble oscillations created by demise of the initially entrained air pocket is examined. Computed spectra are compared to infrasound data from the island of Kauai during periods of medium, large, and extreme surf. Model results suggest that bubble oscillations generated by plunging waves are plausible generators of infrasound, and that dynamic bubble plume evolution on a temporal scale comparable to the breaking wave period may contribute to the broad spectral lobe of dominant infrasonic energy observed in measured data. Application of an inverse model has potential to characterize breaking wave size distributions, energy, and temporal changes in seafloor morphology based on remotely sensed infrasound.

The influence of polymeric membrane gas spargers on hydrodynamics and mass transfer in bubble column bioreactors.

PubMed

Tirunehe, Gossaye; Norddahl, B

2016-04-01

Gas sparging performances of a flat sheet and tubular polymeric membranes were investigated in 3.1 m bubble column bioreactor operated in a semi batch mode. Air-water and air-CMC (Carboxymethyl cellulose) solutions of 0.5, 0.75 and 1.0 % w/w were used as interacting gas-liquid mediums. CMC solutions were employed in the study to simulate rheological properties of bioreactor broth. Gas holdup, bubble size distribution, interfacial area and gas-liquid mass transfer were studied in the homogeneous bubbly flow hydrodynamic regime with superficial gas velocity (U(G)) range of 0.0004-0.0025 m/s. The study indicated that the tubular membrane sparger produced the highest gas holdup and densely populated fine bubbles with narrow size distribution. An increase in liquid viscosity promoted a shift in bubble size distribution to large stable bubbles and smaller specific interfacial area. The tubular membrane sparger achieved greater interfacial area and an enhanced overall mass transfer coefficient (K(L)a) by a factor of 1.2-1.9 compared to the flat sheet membrane.

Intrauterine air impairs embryonic postimplantation development in mice.

PubMed

Liu, Ruonan; Li, Yimeng; Miao, Yanping; Wei, Yanhui; Guan, Mo; Zhou, Rongyan; Li, Xiangyun

2017-12-01

Although most embryologists load air bubbles into the catheter along with embryos during embryo transfer, the effects of these air bubbles on embryo transfer success rate are not clear. Air bubbles were nonsurgically injected into unilateral uterine horns of mice to demonstrate the negative effects of intrauterine air bubbles on embryonic development. Our data showed that when air bubbles are nonsurgically injected into unilateral uterine horns of pregnant 4days mice the litter size is significantly decreased. Four days after the introduction of air, abnormal decidua and dead conceptuses were detected in the uterine horns receiving the air bubbles. In addition, intrauterine air also significantly impaired murine embryo transfer success rates, and induced an increase in endometrial capillary permeability and decidualization in mice on day 4 of pseudopregnancy. These results strongly indicated that the air bubbles loaded into embryo transfer catheters to bracket the embryo-containing medium may have negative effect on embryonic implantation and development. Intrauterine air impaired murine embryonic postimplantation development, and this provided some clues for improving embryo transfer techniques in human. Copyright © 2017 Elsevier B.V. All rights reserved.

Effect of Micro-Bubbles in Water on Beam Patterns of Parametric Array

NASA Astrophysics Data System (ADS)

Hashiba, Kunio; Masuzawa, Hiroshi

2003-05-01

The improvement in efficiency of a parametric array by nonlinear oscillation of micro-bubbles in water is studied in this paper. The micro-bubble oscillation can increase the nonlinear coefficient of the acoustic medium. The amplitude of the difference-frequency wave along the longitudinal axis and its beam patterns in the field including the layer with micro-bubbles were analyzed using a Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation. As a result, the largest improvement in efficiency was obtained and a narrow parametric beam was formed by forming a layer with micro-bubbles in front of a parametric sound radiator as thick as about the shock formation distance. If the layer becomes significantly thicker than the distance, the beam of the difference-frequency wave in the far-field will become broader. If the layer is significantly thinner than the distance, the intensity level of the wave in the far-field will be too low.

Attenuation of low-frequency underwater sound using an array of air-filled balloons and comparison to effective medium theory.

PubMed

Lee, Kevin M; Wilson, Preston S; Wochner, Mark S

2017-12-01

The ultimate goal of this work is to accurately predict the attenuation through a collection of large (on the order of 10-cm-radius) tethered encapsulated bubbles used in underwater noise abatement systems. Measurements of underwater sound attenuation were performed during a set of lake experiments, where a low-frequency compact electromechanical sound source was surrounded by different arrays of encapsulated bubbles with various individual bubbles sizes and void fractions. The measurements were compared with an existing predictive model [Church, J. Acoust. Soc. Am. 97, 1510-1521 (1995)] of the dispersion relation for linear propagation in liquid containing encapsulated bubbles. Although the model was originally intended to describe ultrasound contrast agents, it is evaluated here for large bubbles, and hence low frequencies, as a design tool for future underwater noise abatement systems, and there is good quantitative agreement between the observations and the model.

Critical Evaluation of Air-Liquid Interface Cell Exposure Systems for In Vitro Assessment of Atmospheric Pollutants##

EPA Science Inventory

Conventional in vitro exposure studies of airborne pollutants involve, for example, the addition of particulate matter (PM) or PM extracts to the cell culture medium, or the bubbling of gases into the culture medium; these methods alter the pollutant’s physical and chemical...

Jet formation of SF6 bubble induced by incident and reflected shock waves

NASA Astrophysics Data System (ADS)

Zhu, Yuejin; Yu, Lei; Pan, Jianfeng; Pan, Zhenhua; Zhang, Penggang

2017-12-01

The computational results of two different cases on the evolution of the shock-SF6 heavy bubble interaction are presented. The shock focusing processes and jet formation mechanisms are analyzed by using the high resolution of computation schemes, and the influence of reflected shock waves is also investigated. It is concluded that there are two steps in the shock focusing process behind the incident shock wave, and the density and pressure values increase distinctly when the shock focusing process is completed. The local high pressure and vorticities in the vicinity of the downstream pole can propel the formation of the jet behind the incident shock wave. In addition, the gas is with the rightward velocity before the reflected shock wave impinges on the bubble; therefore, the evolutions of the waves and the bubble are more complicated when the reflected shock wave impinges on the SF6 bubble. Furthermore, the different end wall distances would affect the deformation degree of the bubble before the interaction of the reflected shock wave; therefore, the different left jet formation processes are found after the impingement of reflected shock waves when L = 27 mm. The local high pressure zones in the vicinity of the left bubble interface and the impingement of different shock waves can induce the local gas to shift the rightward velocity to the leftward velocity, which can further promote the formation of jets.

Effect of air bubble localization after transfer on embryo transfer outcomes.

PubMed

Tiras, Bulent; Korucuoglu, Umit; Polat, Mehtap; Saltik, Ayse; Zeyneloglu, Hulusi Bulent; Yarali, Hakan

2012-09-01

Our study aimed to provide information about the effects of air bubble localization after transfer on embryo transfer outcomes. Retrospective analysis of 7489 ultrasound-guided embryo transfers. Group 1 included 6631 embryo transfers in which no movement of the air bubbles was observed after transfer. Group 2 consisted of 407 embryo transfers in which the air bubbles moved towards the uterine fundus spontaneously, a little time after transfer. Group 3 included 370 embryo transfers in which the air bubbles moved towards the uterine fundus with ejection, immediately after transfer. Group 4 consisted of 81 embryo transfers in which the air bubbles moved towards the cervical canal. The four patient groups were different from one another with respect to positive pregnancy tests. Post hoc test revealed that this difference was between group 4 and other groups. An initial finding of our study was significantly decreased positive pregnancy test rates and clinical pregnancy rates with air bubbles moving towards the cervical canal after transfer. Although air bubbles moving towards the uterine fundus with ejection were associated with higher pregnancy rates, higher miscarriage rates and similar live birth rates were observed compared to air bubbles remaining stable after transfer. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Constraints on the gamma-ray emission from the cluster-scale AGN outburst in the Hydra A galaxy cluster

NASA Astrophysics Data System (ADS)

HESS Collaboration; Abramowski, A.; Acero, F.; Aharonian, F.; Akhperjanian, A. G.; Anton, G.; Balenderan, S.; Balzer, A.; Barnacka, A.; Becherini, Y.; Becker, J.; Bernlöhr, K.; Birsin, E.; Biteau, J.; Bochow, A.; Boisson, C.; Bolmont, J.; Bordas, P.; Brucker, J.; Brun, F.; Brun, P.; Bulik, T.; Büsching, I.; Carrigan, S.; Casanova, S.; Cerruti, M.; Chadwick, P. M.; Charbonnier, A.; Chaves, R. C. G.; Cheesebrough, A.; Cologna, G.; Conrad, J.; Couturier, C.; Daniel, M. K.; Davids, I. D.; Degrange, B.; Deil, C.; Dickinson, H. J.; Djannati-Ataï, A.; Domainko, W.; O'C. Drury, L.; Dubus, G.; Dutson, K.; Dyks, J.; Dyrda, M.; Egberts, K.; Eger, P.; Espigat, P.; Fallon, L.; Fegan, S.; Feinstein, F.; Fernandes, M. V.; Fiasson, A.; Fontaine, G.; Förster, A.; Füßling, M.; Gajdus, M.; Gallant, Y. A.; Garrigoux, T.; Gast, H.; Gérard, L.; Giebels, B.; Glicenstein, J. F.; Glück, B.; Göring, D.; Grondin, M.-H.; Häffner, S.; Hague, J. D.; Hahn, J.; Hampf, D.; Harris, J.; Hauser, M.; Heinz, S.; Heinzelmann, G.; Henri, G.; Hermann, G.; Hillert, A.; Hinton, J. A.; Hofmann, W.; Hofverberg, P.; Holler, M.; Horns, D.; Jacholkowska, A.; Jahn, C.; Jamrozy, M.; Jung, I.; Kastendieck, M. A.; Katarzyński, K.; Katz, U.; Kaufmann, S.; Khélifi, B.; Klochkov, D.; Kluźniak, W.; Kneiske, T.; Komin, Nu.; Kosack, K.; Kossakowski, R.; Krayzel, F.; Laffon, H.; Lamanna, G.; Lenain, J.-P.; Lennarz, D.; Lohse, T.; Lopatin, A.; Lu, C.-C.; Marandon, V.; Marcowith, A.; Masbou, J.; Maurin, G.; Maxted, N.; Mayer, M.; McComb, T. J. L.; Medina, M. C.; Méhault, J.; Moderski, R.; Mohamed, M.; Moulin, E.; Naumann, C. L.; Naumann-Godo, M.; de Naurois, M.; Nedbal, D.; Nekrassov, D.; Nguyen, N.; Nicholas, B.; Niemiec, J.; Nolan, S. J.; Ohm, S.; de Oña Wilhelmi, E.; Opitz, B.; Ostrowski, M.; Oya, I.; Panter, M.; Paz Arribas, M.; Pekeur, N. W.; Pelletier, G.; Perez, J.; Petrucci, P.-O.; Peyaud, B.; Pita, S.; Pühlhofer, G.; Punch, M.; Quirrenbach, A.; Raue, M.; Reimer, A.; Reimer, O.; Renaud, M.; de los Reyes, R.; Rieger, F.; Ripken, J.; Rob, L.; Rosier-Lees, S.; Rowell, G.; Rudak, B.; Rulten, C. B.; Sahakian, V.; Sanchez, D. A.; Santangelo, A.; Schlickeiser, R.; Schulz, A.; Schwanke, U.; Schwarzburg, S.; Schwemmer, S.; Sheidaei, F.; Skilton, J. L.; Sol, H.; Spengler, G.; Stawarz, Ł.; Steenkamp, R.; Stegmann, C.; Stinzing, F.; Stycz, K.; Sushch, I.; Szostek, A.; Tavernet, J.-P.; Terrier, R.; Tluczykont, M.; Valerius, K.; van Eldik, C.; Vasileiadis, G.; Venter, C.; Viana, A.; Vincent, P.; Völk, H. J.; Volpe, F.; Vorobiov, S.; Vorster, M.; Wagner, S. J.; Ward, M.; White, R.; Wierzcholska, A.; Zacharias, M.; Zajczyk, A.; Zdziarski, A. A.; Zech, A.; Zechlin, H.-S.; Ali, M. O.

2012-09-01

Context. In some galaxy clusters, powerful active galactic nuclei (AGN) have blown bubbles with cluster scale extent into the ambient medium. The main pressure support of these bubbles is not known to date, but cosmic rays are a viable possibility. For such a scenario copious gamma-ray emission is expected as a tracer of cosmic rays from these systems. Aims: Hydra A, the closest galaxy cluster hosting a cluster scale AGN outburst, located at a redshift of 0.0538, is investigated for being a gamma-ray emitter with the High Energy Stereoscopic System (H.E.S.S.) array and the Fermi Large Area Telescope (Fermi-LAT). Methods: Data obtained in 20.2 h of dedicated H.E.S.S. observations and 38 months of Fermi-LAT data, gathered by its usual all-sky scanning mode, have been analyzed to search for a gamma-ray signal. Results: No signal has been found in either data set. Upper limits on the gamma-ray flux are derived and are compared to models. These are the first limits on gamma-ray emission ever presented for galaxy clusters hosting cluster scale AGN outbursts. Conclusions: The non-detection of Hydra A in gamma-rays has important implications on the particle populations and physical conditions inside the bubbles in this system. For the case of bubbles mainly supported by hadronic cosmic rays, the most favorable scenario, which involves full mixing between cosmic rays and embedding medium, can be excluded. However, hadronic cosmic rays still remain a viable pressure support agent to sustain the bubbles against the thermal pressure of the ambient medium. The largest population of highly-energetic electrons, which are relevant for inverse-Compton gamma-ray production is found in the youngest inner lobes of Hydra A. The limit on the inverse-Compton gamma-ray flux excludes a magnetic field below half of the equipartition value of 16 μG in the inner lobes.

Quenching of a highly superheated porous medium by injection of water

NASA Astrophysics Data System (ADS)

Fichot, F.; Bachrata, A.; Repetto, G.; Fleurot, J.; Quintard, M.

2012-11-01

Understanding of two-phase flow through porous medium with intense phase change is of interest in many situations, including nuclear, chemical or geophysical applications. Intense boiling occurs when the liquid is injected into a highly superheated medium. Under such conditions, the heat flux extracted by the fluid from the porous medium is mainly governed by the nucleation of bubbles and by the evaporation of thin liquid films. Both configurations are possible, depending on local flow conditions and on the ratio of bubble size to pore size. The present study is motivated by the safety evaluation of light water nuclear reactors in case of a severe accident scenario, such as the one that happened in Fukushima Dai-ichi plant in March, 2011. If water sources are not available for a long period of time, the reactor core heats up due to the residual power and eventually becomes significantly damaged due to intense oxidation of metals and fragmentation of fuel rods resulting in the formation of a porous medium where the particles have a characteristic length-scale of 1 to 5 mm. The coolability of the porous medium will depend on the water flow rate which can enter the medium under the available driving head and on the geometrical features of the porous matrix (average pore size, porosity). Therefore, it is of high interest to evaluate the conditions for which the injection of water in such porous medium is likely to stop the progression of the accident. The present paper addresses the issue of modelling two-phase flow and heat transfers in a porous medium initially dry, where water is injected. The medium is initially at a temperature well above the saturation temperature of water. In a first part, a summary of existing knowledge is provided, showing the scarcity of models and experimental data. In a second part, new experimental results obtained in an IRSN facility are analysed. The experiment consists in a bed of steel particles that are heated up to 700°Cbefore injecting water. The facility is briefly described. The velocity of the "quench front" (location where particles are quickly cooled down) and the total pressure drop across the medium are estimated. The dependencies of those quantities with respect to the inlet water flow rate, the initial temperature of the medium and the diameter of particles are obtained. In a third part, a model is proposed, based on a previously developed model which is improved in order to take into account intense boiling regimes (in particular nucleate boiling). The model includes a function that takes into account the contact area between water and the particles which depends on the temperature of particles and on the void fraction. That function affects the local intensity of phase change. The model involves a few parameters which cannot be evaluated analytically. Those parameters are bounded, following the analysis of experimental data. Finally, the model is assessed by comparison of calculations with those new experimental data. The satisfactory agreement shows that the model is almost predictive in the range of parameters studied. The experimental results also show that the quench front becomes unstable under certain conditions. This is also analysed and compared with the predictions of the model.

First exploration of a single thermal interface between the two dominant phases of the interstellar medium

NASA Astrophysics Data System (ADS)

Gry, Cecile

2017-08-01

Two phases of the interstellar medium, the Warm Neutral Medium (WNM) and the Hot Ionized Medium (HIM) occupy most the volume of space in the plane of our Galaxy. Because the boundaries between these phases are important sources of energy loss for the hot gas, they are supposed to play an important role in the thermal structure and evolution of the ISM and of galaxies.Many theorists have created descriptions of the nature of such boundaries and have derived two fundamental concepts: (1) a conductive interface and (2) a turbulent mixing layer.We have yet to observe in detail either kind of boundary. This is achieved by using UV absorption lines of moderately high ionization stages of heavy elements. Yet, over most lines of sight the diagnostics are blurred out by the superposition of different regions with vastly different physical conditions, making them difficult to interpret. To characterize the nature of the physical processes at a boundary one must observe along a sight line that penetrates just one such region. The simplest configuration is the outer boundary of the Local Cloud, the WNM ((T 7000 K) that surrounds the Sun and which is embedded in a very low density, soft X-ray emitting hot medium ( 10^6 K) that fills a cavity ( 200 pc in diameter) called the Local Bubble.We propose to observe an ideal target: a nearby, bright B9V star (i.e. hot enough to provide a high-SNR continuum, but not enough to contaminate it with absorptions from circumstellar high-ionization species), located in a direction where the relative orientation of the magnetic field and the cloud boundary does not quench thermal conduction and thus favors a full extent of the interface.

Gentle Heating by Mixing in Cooling Flow Clusters

NASA Astrophysics Data System (ADS)

Hillel, Shlomi; Soker, Noam

2017-08-01

We analyze 3D hydrodynamical simulations of the interaction of jets and the bubbles they inflate with the intracluster medium (ICM) and show that the heating of the ICM by mixing hot bubble gas with the ICM operates over tens of millions of years and hence can smooth the sporadic activity of the jets. The inflation process of hot bubbles by propagating jets forms many vortices, and these vortices mix the hot bubble gas with the ICM. The mixing, and hence the heating of the ICM, starts immediately after the jets are launched, but continues for tens of millions of years. We suggest that the smoothing of the active galactic nucleus (AGN) sporadic activity by the long-lived vortices accounts for the recent finding of a gentle energy coupling between AGN heating and the ICM.

The variance of dispersion measure of high-redshift transient objects as a probe of ionized bubble size during reionization

NASA Astrophysics Data System (ADS)

Yoshiura, Shintaro; Takahashi, Keitaro

2018-01-01

The dispersion measure (DM) of high-redshift (z ≳ 6) transient objects such as fast radio bursts can be a powerful tool to probe the intergalactic medium during the Epoch of Reionization. In this paper, we study the variance of the DMs of objects with the same redshift as a potential probe of the size distribution of ionized bubbles. We calculate the DM variance with a simple model with randomly distributed spherical bubbles. It is found that the DM variance reflects the characteristics of the probability distribution of the bubble size. We find that the variance can be measured precisely enough to obtain the information on the typical size with a few hundred sources at a single redshift.

An X-ray image of the violent interstellar medium in 30 Doradus

NASA Technical Reports Server (NTRS)

Wang, Q.; Helfand, D. J.

1991-01-01

A detailed analysis of the X-ray emission from the largest H II region complex in the Local Group, 30 Dor, is presented. Applying a new maximum entropy deconvolution algorithm to the Einstein Observatory data, reveals striking correlations among the X-ray, radio, and optical morphologies of the region, with X-ray-emitting bubbles filling cavities surrounded by H-alpha shells and coextensive diffuse X-ray and radio continuum emission from throughout the region. The total X-ray luminosity in the 0.16-3.5 keV band from an area within 160 pc of the central cluster R136 is about 2 x 10 to the 37th ergs/sec.

The Ultra-Soft X-ray Background: A Probe of the Hot Interstellar Medium and the Local Bubble - ADP-99

NASA Technical Reports Server (NTRS)

Smith, Randall

2003-01-01

The Ultra-Soft X-ray Telescope (UXT) was a sounding rocket mission flown three times in 1984 - 1986. At the beginning of the project, the data existed solely in form of raw telemetry data stored on 9 track tapes. The primary goal of this proposal has been to extract event files from the raw telemetry stream and to create instrument response models and calibrated spectra from it. We have completed this project, and the data will soon be available to all via the HEASARC archive of high-energy data at Goddard Space Flight Center. We are in the process of combining the results with the ALEXIS and DXS observations of the Local Bubble in modelling the 72 eV iron line (recently observed by the X-ray Quantum Calorimeter) and the carbon emission lines that are uniquely visible in this dataset. Our results agree with the XQC observation which predicts a maximum emission in the 72 eV iron lines that is below the limit observable with UXT. However, this leaves an open question as to what lines were responsible for the observed Be-band emission. The answer to this question will likely require more observations of soft X-rays with the Chandra LETGS and new atomic data models of potentially emitting ions.

Growth and setting of gas bubbles in a viscoelastic matrix imaged by X-ray microtomography: the evolution of cellular structures in fermenting wheat flour dough.

PubMed

Turbin-Orger, A; Babin, P; Boller, E; Chaunier, L; Chiron, H; Della Valle, G; Dendievel, R; Réguerre, A L; Salvo, L

2015-05-07

X-ray tomography is a relevant technique for the dynamic follow-up of gas bubbles in an opaque viscoelastic matrix, especially using image analysis. It has been applied here to pieces of fermenting wheat flour dough of various compositions, at two different voxel sizes (15 and 5 μm). The resulting evolution of the main cellular features shows that the creation of cellular structures follows two regimes that are defined by a characteristic time of connectivity, tc [30 and 80 min]: first (t ≤ tc), bubbles grow freely and then (t ≥ tc) they become connected since the percolation of the gas phase is limited by liquid films. During the first regime, bubbles can be tracked and the local strain rate can be measured. Its values (10(-4)-5 × 10(-4) s(-1)) are in agreement with those computed from dough viscosity and internal gas pressure, both of which depend on the composition. For higher porosity, P = 0.64 in our case, and thus occurring in the second regime, different cellular structures are obtained and XRT images show deformed gas cells that display complex shapes. The comparison of these images with confocal laser scanning microscopy images suggests the presence of liquid films that separate these cells. The dough can therefore be seen as a three-phase medium: viscoelastic matrix/gas cell/liquid phase. The contributions of the different levels of matter organization can be integrated by defining a capillary number (C = 0.1-1) that makes it possible to predict the macroscopic dough behavior.

Bubble-based acoustic radiation force using chirp insonation to reduce standing wave effects.

PubMed

Erpelding, Todd N; Hollman, Kyle W; O'Donnell, Matthew

2007-02-01

Bubble-based acoustic radiation force can measure local viscoelastic properties of tissue. High intensity acoustic waves applied to laser-generated bubbles induce displacements inversely proportional to local Young's modulus. In certain instances, long pulse durations are desirable but are susceptible to standing wave artifacts, which corrupt displacement measurements. Chirp pulse acoustic radiation force was investigated as a method to reduce standing wave artifacts. Chirp pulses with linear frequency sweep magnitudes of 100, 200 and 300 kHz centered around 1.5 MHz were applied to glass beads within gelatin phantoms and laser-generated bubbles within porcine lenses. The ultrasound transducer was translated axially to vary standing wave conditions, while comparing displacements using chirp pulses and 1.5 MHz tone burst pulses of the same duration and peak rarefactional pressure. Results demonstrated significant reduction in standing wave effects using chirp pulses, with displacement proportional to acoustic intensity and bubble size.

Bubble-Based Acoustic Radiation Force Using Chirp Insonation to Reduce Standing Wave Effects

PubMed Central

Erpelding, Todd N.; Hollman, Kyle W.; O’Donnell, Matthew

2007-01-01

Bubble-based acoustic radiation force can measure local viscoelastic properties of tissue. High intensity acoustic waves applied to laser-generated bubbles induce displacements inversely proportional to local Young’s modulus. In certain instances, long pulse durations are desirable but are susceptible to standing wave artifacts, which corrupt displacement measurements. Chirp pulse acoustic radiation force was investigated as a method to reduce standing wave artifacts. Chirp pulses with linear frequency sweep magnitudes of 100, 200, and 300 kHz centered around 1.5 MHz were applied to glass beads within gelatin phantoms and laser-generated bubbles within porcine lenses. The ultrasound transducer was translated axially to vary standing wave conditions, while comparing displacements using chirp pulses and 1.5 MHz tone burst pulses of the same duration and peak rarefactional pressure. Results demonstrated significant reduction in standing wave effects using chirp pulses, with displacement proportional to acoustic intensity and bubble size. PMID:17306697

Bubble induced flow field modulation for pool boiling enhancement over a tubular surface

NASA Astrophysics Data System (ADS)

Raghupathi, P. A.; Joshi, I. M.; Jaikumar, A.; Emery, T. S.; Kandlikar, S. G.

2017-06-01

We demonstrate the efficacy of using a strategically placed enhancement feature to modify the trajectory of bubbles nucleating on a horizontal tubular surface to increase both the critical heat flux (CHF) and the heat transfer coefficient (HTC). The CHF on a plain tube is shown to be triggered by a local dryout at the bottom of the tube due to vapor agglomeration. To mitigate this effect and delay CHF, the nucleating bubble trajectory is modified by incorporating a bubble diverter placed axially at the bottom of the tube. The nucleating bubble at the base of the diverter experiences a tangential evaporation momentum force (EMF) which causes the bubble to grow sideways away from the tube and avoid localized bubble patches that are responsible for CHF initiation. High speed imaging confirmed the lateral displacement of the bubbles away from the diverter closely matched with the theoretical predictions using EMF and buoyancy forces. Since the EMF is stronger at higher heat fluxes, bubble displacement increases with heat flux and results in the formation of separate liquid-vapor pathways wherein the liquid enters almost unobstructed at the bottom and the vapor bubble leaves sideways. Experimental results yielded CHF and HTC enhancements of ˜60% and ˜75%, respectively, with the diverter configuration when compared to a plain tube. This work can be used for guidance in developing enhancement strategies to effectively modulate the liquid-vapor flow around the heater surface at various locations to enhance HTC and CHF.

An Euler-Lagrange method considering bubble radial dynamics for modeling sonochemical reactors.

PubMed

Jamshidi, Rashid; Brenner, Gunther

2014-01-01

Unsteady numerical computations are performed to investigate the flow field, wave propagation and the structure of bubbles in sonochemical reactors. The turbulent flow field is simulated using a two-equation Reynolds-Averaged Navier-Stokes (RANS) model. The distribution of the acoustic pressure is solved based on the Helmholtz equation using a finite volume method (FVM). The radial dynamics of a single bubble are considered by applying the Keller-Miksis equation to consider the compressibility of the liquid to the first order of acoustical Mach number. To investigate the structure of bubbles, a one-way coupling Euler-Lagrange approach is used to simulate the bulk medium and the bubbles as the dispersed phase. Drag, gravity, buoyancy, added mass, volume change and first Bjerknes forces are considered and their orders of magnitude are compared. To verify the implemented numerical algorithms, results for one- and two-dimensional simplified test cases are compared with analytical solutions. The results show good agreement with experimental results for the relationship between the acoustic pressure amplitude and the volume fraction of the bubbles. The two-dimensional axi-symmetric results are in good agreement with experimentally observed structure of bubbles close to sonotrode. Copyright © 2013 Elsevier B.V. All rights reserved.

Evaluation of stability and size distribution of sunflower oil-coated micro bubbles for localized drug delivery.

PubMed

Filho, Walter Duarte de Araujo; Schneider, Fábio Kurt; Morales, Rigoberto E M

2012-09-20

Micro bubbles were initially introduced as contrast agents for ultrasound examinations as they are able to modify the signal-to-noise ratio in imaging, thus improving the assessment of clinical information on human tissue. Recent developments have demonstrated the feasibility of using these bubbles as drug carriers in localized delivery. In micro fluidics devices for generation of micro bubbles, the bubbles are formed at interface of liquid gas through a strangulation process. A device that uses these features can produce micro bubbles with small size dispersion in a single step. A T-junction micro fluidic device constructed using 3D prototyping was made for the production of mono dispersed micro bubbles. These micro bubbles use sunflower oil as a lipid layer. Stability studies for micro bubbles with diameters different generated from a liquid phase of the same viscosity were conducted to evaluate whether micro bubbles can be used as drug carriers. The biocompatibility of coating layer, the ability to withstand environmental pressure variations combined with echogenicity, are key factors that they can safely play the role of drug transporters. The normal distribution curve with small dispersion of the diameter of bubbles validates the process of generating micro bubbles with low value of variation coefficient, i.e., 0.381 at 1.90%. The results also showed the feasibility of using sunflower oil as the lipid matrix with stable population of bubbles over 217 minutes for micro bubbles with an average diameter of 313.04 μm and 121 minutes for micro bubbles with an average diameter of 73.74 μm, considering bubbles with air as gaseous phase. The results indicate that the micro fluidic device designed can be used for producing micro bubbles with low variation coefficient using sunflower oil as a coating of micro bubbles. These carriers were stable for periods of time that are long enough for clinical applications even when regular air is used as the gas phase. Improved stability can be achieved when biocompatible gas with lower permeability is used.

Fast coliform detection in portable microbe enrichment unit (PMEU) with Colilert(®) medium and bubbling.

PubMed

Hakalehto, Elias; Heitto, Anneli; Heitto, Lauri

2013-09-01

Laboratory strains of coliforms Escherichia coli and Klebsiella mobilis were used to artificially contaminate water samples in two different cultivation and detection systems, without and with bubble flow. Samples were collected with an automated system (ASCS). The positive coliform signal caused the color change into yellow (at 550-570nm). This signal could also be transmitted on-line to cell phones. E. coli containing samples emitted UV fluorescence at 480-560nm when activated by UV light. If cultivation was started with inocula varying from 10,000 to 1cfu/ml, the positive detection was obtained between 2 and 18h, respectively, in Colilert medium using Coline PMEU device without gas bubbling. Accordingly, a single K. mobilis cell produced detectable growth in 18h. Various clinical E. coli strains were compared to each other with equal inoculum sizes, and they showed slight variations in the initiation and speed of growth. The gas bubble flow in PMEU Spectrion promoted the mixing and interaction of bacteria and indicator media and speeded the onset of growth. Carbon dioxide also accelerated bacterial growth. In the presence of vancomycin, the onset of E. coli culture growth was speeded up by the volatile outlet flow from previous cultures. In the last cultivation syringe in a series of five, the lag phase disappeared and the growth of the inoculum continued without major interruption. the stimulation of the cultures by the gas flow turned out to be a useful means for improving the detection of indicator bacteria. It could also be used in combination with antibiotic selection in the broth medium. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Theoretical model of ice nucleation induced by acoustic cavitation. Part 1: Pressure and temperature profiles around a single bubble.

PubMed

Cogné, C; Labouret, S; Peczalski, R; Louisnard, O; Baillon, F; Espitalier, F

2016-03-01

This paper deals with the inertial cavitation of a single gas bubble in a liquid submitted to an ultrasonic wave. The aim was to calculate accurately the pressure and temperature at the bubble wall and in the liquid adjacent to the wall just before and just after the collapse. Two different approaches were proposed for modeling the heat transfer between the ambient liquid and the gas: the simplified approach (A) with liquid acting as perfect heat sink, the rigorous approach (B) with liquid acting as a normal heat conducting medium. The time profiles of the bubble radius, gas temperature, interface temperature and pressure corresponding to the above models were compared and important differences were observed excepted for the bubble size. The exact pressure and temperature distributions in the liquid corresponding to the second model (B) were also presented. These profiles are necessary for the prediction of any physical phenomena occurring around the cavitation bubble, with possible applications to sono-crystallization. Copyright © 2015 Elsevier B.V. All rights reserved.

Sound propagation in water containing large tethered spherical encapsulated gas bubbles with resonance frequencies in the 50 Hz to 100 Hz range.

PubMed

Lee, Kevin M; Hinojosa, Kevin T; Wochner, Mark S; Argo, Theodore F; Wilson, Preston S; Mercier, Richard S

2011-11-01

The efficacy of large tethered encapsulated gas bubbles for the mitigation of low frequency underwater noise was investigated with an acoustic resonator technique. Tethered latex balloons were used as the bubbles, which had radii of approximately 5 cm. Phase speeds were inferred from the resonances of a water and balloon-filled waveguide approximately 1.8 m in length. The Commander and Prosperetti effective-medium model [J. Acoust. Soc. Am. 85, 732-746 (1989)] quantitatively described the observed dispersion from well below to just below the individual bubble resonance frequency, and it qualitatively predicted the frequency range of high attenuation for void fractions between 2% and 5% for collections of stationary balloons within the waveguide. A finite-element model was used to investigate the sensitivity of the waveguide resonance frequencies, and hence the inferred phase speeds, to changes in individual bubble size and position. The results indicate that large tethered encapsulated bubbles could be used mitigate low frequency underwater noise and that the Commander and Prosperetti model would be useful in the design of such a system.

Localized and delocalized motion of colloidal particles on a magnetic bubble lattice.

PubMed

Tierno, Pietro; Johansen, Tom H; Fischer, Thomas M

2007-07-20

We study the motion of paramagnetic colloidal particles placed above magnetic bubble domains of a uniaxial garnet film and driven through the lattice by external magnetic field modulation. An external tunable precessing field propels the particles either in localized orbits around the bubbles or in superdiffusive or ballistic motion through the bubble array. This motion results from the interplay between the driving rotating signal, the viscous drag force and the periodic magnetic energy landscape. We explain the transition in terms of the incommensurability between the transit frequency of the particle through a unit cell and the modulation frequency. Ballistic motion dynamically breaks the symmetry of the array and the phase locked particles follow one of the six crystal directions.

First Study on the Occurrence Frequency of Equatorial Plasma Bubbles over West Africa Using an All-Sky Airglow Imager and GNSS Receivers

NASA Astrophysics Data System (ADS)

Okoh, Daniel; Rabiu, Babatunde; Shiokawa, Kazuo; Otsuka, Yuichi; Segun, Bolaji; Falayi, Elijah; Onwuneme, Sylvester; Kaka, Rafiat

2017-12-01

This is the first paper that reports the occurrence frequency of equatorial plasma bubbles and their dependences of local time, season, and geomagnetic activity based on airglow imaging observations at West Africa. The all-sky imager, situated in Abuja (Geographic: 8.99°N, 7.38°E; Geomagnetic: 1.60°S), has a 180° fisheye view covering almost the entire airspace of Nigeria. Plasma bubbles are observed for 70 nights of the 147 clear-sky nights from 9 June 2015 to 31 January 2017. Differences between nighttime and daytime ROTIs were also computed as a proxy of plasma bubbles using Global Navigation Satellite Systems (GNSS) receivers within the coverage of the all-sky imager. Most plasma bubble occurrences are found during equinoxes and least occurrences during solstices. The occurrence rate of plasma bubbles was highest around local midnight and lower for hours farther away. Most of the postmidnight plasma bubbles were observed around the months of December to March, a period that coincides with the harmattan period in Nigeria. The on/off status of plasma bubble in airglow and GNSS observations were in agreement for 67.2% of the total 768 h, while we suggest several reasons responsible for the remaining 32.8% when the airglow and GNSS bubble status are inconsistent. A majority of the plasma bubbles were observed under relatively quiet geomagnetic conditions (Dst ≥ -40 and Kp ≤ 3), but there was no significant pattern observed in the occurrence rate of plasma bubbles as a function of geomagnetic activity. We suggest that geomagnetic activities could have either suppressed or promoted the occurrence of plasma bubbles.

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)-Cell Interaction and the Resultant Bioeffects at the Single-cell Level.

PubMed

Li, Fenfang; Yuan, Fang; Sankin, Georgy; Yang, Chen; Zhong, Pei

2017-01-10

In this manuscript, we first describe the fabrication protocol of a microfluidic chip, with gold dots and fibronectin-coated regions on the same glass substrate, that precisely controls the generation of tandem bubbles and individual cells patterned nearby with well-defined locations and shapes. We then demonstrate the generation of tandem bubbles by using two pulsed lasers illuminating a pair of gold dots with a few-microsecond time delay. We visualize the bubble-bubble interaction and jet formation by high-speed imaging and characterize the resultant flow field using particle image velocimetry (PIV). Finally, we present some applications of this technique for single cell analysis, including cell membrane poration with macromolecule uptake, localized membrane deformation determined by the displacements of attached integrin-binding beads, and intracellular calcium response from ratiometric imaging. Our results show that a fast and directional jetting flow is produced by the tandem bubble interaction, which can impose a highly localized shear stress on the surface of a cell grown in close proximity. Furthermore, different bioeffects can be induced by altering the strength of the jetting flow by adjusting the standoff distance from the cell to the tandem bubbles.

Raman Spectral Band Oscillations in Large Graphene Bubbles

NASA Astrophysics Data System (ADS)

Huang, Yuan; Wang, Xiao; Zhang, Xu; Chen, Xianjue; Li, Baowen; Wang, Bin; Huang, Ming; Zhu, Chongyang; Zhang, Xuewei; Bacsa, Wolfgang S.; Ding, Feng; Ruoff, Rodney S.

2018-05-01

Raman spectra of large graphene bubbles showed size-dependent oscillations in spectral intensity and frequency, which originate from optical standing waves formed in the vicinity of the graphene surface. At a high laser power, local heating can lead to oscillations in the Raman frequency and also create a temperature gradient in the bubble. Based on Raman data, the temperature distribution within the graphene bubble was calculated, and it is shown that the heating effect of the laser is reduced when moving from the center of a bubble to its edge. By studying graphene bubbles, both the thermal conductivity and chemical reactivity of graphene were assessed. When exposed to hydrogen plasma, areas with bubbles are found to be more reactive than flat graphene.

Effect of hydrodynamic cavitation in the tissue erosion by pulsed high-intensity focused ultrasound (pHIFU).

PubMed

Zhou, Yufeng; Gao, Xiaobin Wilson

2016-09-21

High-intensity focused ultrasound (HIFU) is emerging as an effective therapeutic modality in clinics. Besides the thermal ablation, tissue disintegration is also possible because of the interaction between the distorted HIFU bursts and either bubble cloud or boiling bubble. Hydrodynamic cavitation is another type of cavitation and has been employed widely in industry, but its role in mechanical erosion to tissue is not clearly known. In this study, the bubble dynamics immediately after the termination of HIFU exposure in the transparent gel phantom was captured by high-speed photography, from which the bubble displacement towards the transducer and the changes of bubble size was quantitatively determined. The characteristics of hydrodynamic cavitation due to the release of the acoustic radiation force and relaxation of compressed surrounding medium were found to associate with the number of pulses delivered and HIFU parameters (i.e. pulse duration and pulse repetition frequency). Because of the initial big bubble (~1 mm), large bubble expansion (up to 1.76 folds), and quick bubble motion (up to ~1 m s -1 ) hydrodynamic cavitation is significant after HIFU exposure and may lead to mechanical erosion. The shielding effect of residual tiny bubbles would reduce the acoustic energy delivered to the pre-existing bubble at the focus and, subsequently, the hydrodynamic cavitation effect. Tadpole shape of mechanical erosion in ex vivo porcine kidney samples was similar to the contour of bubble dynamics in the gel. Liquefied tissue was observed to emit towards the transducer through the punctured tissue after HIFU exposure in the sonography. In summary, the release of HIFU exposure-induced hydrodynamic cavitation produces significant bubble expansion and motion, which may be another important mechanism of tissue erosion. Understanding its mechanism and optimizing the outcome would broaden and enhance HIFU applications.

Effect of hydrodynamic cavitation in the tissue erosion by pulsed high-intensity focused ultrasound (pHIFU)

NASA Astrophysics Data System (ADS)

Zhou, Yufeng; Gao, Xiaobin Wilson

2016-09-01

High-intensity focused ultrasound (HIFU) is emerging as an effective therapeutic modality in clinics. Besides the thermal ablation, tissue disintegration is also possible because of the interaction between the distorted HIFU bursts and either bubble cloud or boiling bubble. Hydrodynamic cavitation is another type of cavitation and has been employed widely in industry, but its role in mechanical erosion to tissue is not clearly known. In this study, the bubble dynamics immediately after the termination of HIFU exposure in the transparent gel phantom was captured by high-speed photography, from which the bubble displacement towards the transducer and the changes of bubble size was quantitatively determined. The characteristics of hydrodynamic cavitation due to the release of the acoustic radiation force and relaxation of compressed surrounding medium were found to associate with the number of pulses delivered and HIFU parameters (i.e. pulse duration and pulse repetition frequency). Because of the initial big bubble (~1 mm), large bubble expansion (up to 1.76 folds), and quick bubble motion (up to ~1 m s-1) hydrodynamic cavitation is significant after HIFU exposure and may lead to mechanical erosion. The shielding effect of residual tiny bubbles would reduce the acoustic energy delivered to the pre-existing bubble at the focus and, subsequently, the hydrodynamic cavitation effect. Tadpole shape of mechanical erosion in ex vivo porcine kidney samples was similar to the contour of bubble dynamics in the gel. Liquefied tissue was observed to emit towards the transducer through the punctured tissue after HIFU exposure in the sonography. In summary, the release of HIFU exposure-induced hydrodynamic cavitation produces significant bubble expansion and motion, which may be another important mechanism of tissue erosion. Understanding its mechanism and optimizing the outcome would broaden and enhance HIFU applications.

High-average-power laser medium based on silica glass

NASA Astrophysics Data System (ADS)

Fujimoto, Yasushi; Nakatsuka, Masahiro

2000-01-01

Silica glass is one of the most attractive materials for a high-average-power laser. We have developed a new laser material base don silica glass with zeolite method which is effective for uniform dispersion of rare earth ions in silica glass. High quality medium, which is bubbleless and quite low refractive index distortion, must be required for realization of laser action. As the main reason of bubbling is due to hydroxy species remained in the gelation same, we carefully choose colloidal silica particles, pH value of hydrochloric acid for hydrolysis of tetraethylorthosilicate on sol-gel process, and temperature and atmosphere control during sintering process, and then we get a bubble less transparent rare earth doped silica glass. The refractive index distortion of the sample also discussed.

The Wolf-Rayet nebula NGC 3199 - an interstellar snow plough?

NASA Astrophysics Data System (ADS)

Dyson, J. E.; Ghanbari, J.

1989-12-01

The Wolf-Rayet nebula NGC 3199 has a highly asymmetric morphology, with a very bright hemisphere near the exciting star HD 89358 and a much fainter and more extended other hemisphere. This nebula is modeled in terms of the distorted bubble produced by a moving star blowing a strong stellar wind into a surrounding uniform interstellar medium; this model is fitted to the morphology and observed kinematic data. The exciting star appears to be moving at about 60 km/s into local interstellar gas of density of about 10/cu cm, and has a mass-loss rate of about 0.000027 solar mass/yr. This latter mass-loss rate is in excellent agreement with observed mass-loss rates from Wolf-Rayet stars.

Bubbly cavitating flow generation and investigation of its erosional nature for biomedical applications.

PubMed

Koşar, Ali; Şeşen, Muhsincan; Oral, Ozlem; Itah, Zeynep; Gozuacik, Devrim

2011-05-01

This paper presents a study that investigates the destructive energy output resulting from hydrodynamic bubbly cavitation in microchannels and its potential use in biomedical applications. The research performed in this study includes results from bubbly cavitation experiments and findings showing the destructive effects of bubbly cavitating flow on selected solid specimens and live cells. The bubbles generated by hydrodynamic cavitation are highly destructive at the surfaces of the target medium on which they are carefully focused. The resulting destructive energy output could be effectively used for biomedical treatments, such as destroying kidney stones (renal calculi) or killing cancer cells. Motivated by this potential, the cavitation damage to cancerous cells and material removal from chalk pieces (which possess similar material properties as some kidney stones) was investigated. Our results showed that cavitation could induce damage both on chalk pieces and leukemia/lymphoma cells. We discovered that hydrodynamic cavitation exposure had early and delayed effects on cancer cell survival. Hence, the potential of hydrodynamic bubbly cavitation generated at the microscale for biomedical treatments was revealed using the microchannel configuration as a microorifice (with an inner diameter of 147 μm and a length of 1.52 cm), which acts as the source of bubbly cavitating flows. © 2011 IEEE

Ideal Magnetohydrodynamic Simulations of Magnetic Bubble Expansion as a Model for Extragalactic Radio Lobes

NASA Astrophysics Data System (ADS)

Liu, Wei; Hsu, Scott; Li, Hui; Li, Shengtai; Lynn, Alan

2009-05-01

Recent astronomical observations indicate that radio lobes are gigantic relaxed magnetized plasmas with kilo-to-megaparsec scale jets providing a source of magnetic energy from the galaxy to the lobes. Therefore we are conducting a laboratory plasma experiment, the Plasma Bubble Expansion Experiment (PBEX) in which a higher pressure magnetized plasma bubble (i.e., the lobe) is injected into a lower pressure background plasma (i.e., the intergalactic medium) to study key nonlinear plasma physics issues. Here we present detailed ideal magnetohydrodynamic (MHD) three-dimensional simulations of PBEX. First, the direction of bubble expansion depends on the ratio of the bubble toroidal to poloidal magnetic field, with a higher ratio leading to expansion predominantly in the direction of propagation and a lower ratio leading to expansion predominantly normal to the direction of propagation. Second, a leading MHD shock and a trailing slow-mode compressible MHD wave front are formed ahead of the bubble as it propagates into the background plasma. Third, the bubble expansion and propagation develop asymmetries about its propagation axis due to reconnection arising from numerical resistivity and to inhomogeneous angular momentum transport due to the background magnetic field. These results will help guide the initial experiments and diagnostic measurements on PBEX.

System for Manipulating Drops and Bubbles Using Acoustic Radiation Pressure

NASA Technical Reports Server (NTRS)

Oeftering, Richard C. (Inventor)

1999-01-01

The manipulation and control of drops of liquid and gas bubbles is achieved using high intensity acoustics in the form of and/or acoustic radiation pressure and acoustic streaming. generated by a controlled wave emission from a transducer. Acoustic radiation pressure is used to deploy or dispense drops into a liquid or a gas or bubbles into a liquid at zero or near zero velocity from the discharge end of a needle such as a syringe needle. Acoustic streaming is useful in manipulating the drop or bubble during or after deployment. Deployment and discharge is achieved by focusing the acoustic radiation pressure on the discharge end of the needle, and passing the acoustic waves through the fluid in the needle. through the needle will itself, or coaxially through the fluid medium surrounding the needle. Alternatively, the acoustic waves can be counter-deployed by focusing on the discharge end of the needle from a transducer axially aligned with the needle, but at a position opposite the needle, to prevent premature deployment of the drop or bubble. The acoustic radiation pressure can also be used for detecting the presence or absence of a drop or a bubble at the tip of a needle or for sensing various physical characteristics of the drop or bubble such as size or density.

Simulation of the ultrasound-induced growth and collapse of a near-wall bubble

NASA Astrophysics Data System (ADS)

Boyd, Bradley; Becker, Sid

2017-11-01

In this study, we consider the acoustically driven growth and collapse of a cavitation bubble in a fluid medium exposed to an ultrasound field. The bubble dynamics are modelled using a compressible, inviscid, multiphase model. The numerical scheme consists of a conservative interface capturing scheme which uses the fifth-order WENO reconstruction with a maximum-principle-satisfying and positivity-preserving limiter, and the HLLC approximate Riemann flux. To model the ultrasound input, a moving boundary oscillates through a fixed grid of finite-volume cells. The growth phase of the simulation shows the rapid non-spherical growth of the near-wall bubble. Once the bubble reaches its maximum size and the collapse phase begins, the simulation shows the formation of a jet which penetrates the bubble towards the wall at the later stages of the collapse. For a bubble with an initial radius of 50 μ m and an ultrasound pressure amplitude of 200 kPa, the pressure experienced by the wall increased rapidly nearing the end of the collapse, reaching a peak pressure of 13 MPa. This model is an important development in the field as it represents the physics of acoustic cavitation in more detail than before. This work was supported by the Royal Society of New Zealand's Marsden Fund.

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)-Cell Interaction and the Resultant Bioeffects at the Single-Cell Level

PubMed Central

Li, Fenfang; Yuan, Fang; Sankin, Georgy; Yang, Chen; Zhong, Pei

2017-01-01

In this manuscript, we first describe the fabrication protocol of a microfluidic chip, with gold dots and fibronectin-coated regions on the same glass substrate that precisely controls the generation of tandem bubbles and individual cells patterned nearby with well-defined locations and shapes. We then demonstrate the generation of tandem bubbles by using two pulsed lasers illuminating a pair of gold dots with a few-microsecond time delay. We visualize the bubble-bubble interaction and jet formation by high-speed imaging and characterize the resultant flow field using particle image velocimetry (PIV). Finally, we present some applications of this technique for single cell analysis, including cell membrane poration with macromolecule uptake, localized membrane deformation determined by the displacements of attached integrin-binding beads, and intracellular calcium response from ratiometric imaging. Our results show that a fast and directional jetting flow is produced by the tandem bubble interaction, which can impose a highly-localized shear stress on the surface of a cell grown in close proximity. Furthermore, different bioeffects can be induced by altering the strength of the jetting flow by adjusting the standoff distance from the cell to the tandem bubbles. PMID:28117807

A physics based multiscale modeling of cavitating flows.

PubMed

Ma, Jingsen; Hsiao, Chao-Tsung; Chahine, Georges L

2017-03-02

Numerical modeling of cavitating bubbly flows is challenging due to the wide range of characteristic lengths of the physics at play: from micrometers (e.g., bubble nuclei radius) to meters (e.g., propeller diameter or sheet cavity length). To address this, we present here a multiscale approach which integrates a Discrete Singularities Model (DSM) for dispersed microbubbles and a two-phase Navier Stokes solver for the bubbly medium, which includes a level set approach to describe large cavities or gaseous pockets. Inter-scale schemes are used to smoothly bridge the two transitioning subgrid DSM bubbles into larger discretized cavities. This approach is demonstrated on several problems including cavitation inception and vapor core formation in a vortex flow, sheet-to-cloud cavitation over a hydrofoil, cavitation behind a blunt body, and cavitation on a propeller. These examples highlight the capabilities of the developed multiscale model in simulating various form of cavitation.

A physics based multiscale modeling of cavitating flows

PubMed Central

Ma, Jingsen; Hsiao, Chao-Tsung; Chahine, Georges L.

2018-01-01

Numerical modeling of cavitating bubbly flows is challenging due to the wide range of characteristic lengths of the physics at play: from micrometers (e.g., bubble nuclei radius) to meters (e.g., propeller diameter or sheet cavity length). To address this, we present here a multiscale approach which integrates a Discrete Singularities Model (DSM) for dispersed microbubbles and a two-phase Navier Stokes solver for the bubbly medium, which includes a level set approach to describe large cavities or gaseous pockets. Inter-scale schemes are used to smoothly bridge the two transitioning subgrid DSM bubbles into larger discretized cavities. This approach is demonstrated on several problems including cavitation inception and vapor core formation in a vortex flow, sheet-to-cloud cavitation over a hydrofoil, cavitation behind a blunt body, and cavitation on a propeller. These examples highlight the capabilities of the developed multiscale model in simulating various form of cavitation. PMID:29720773

Bubbles in Sediments

DTIC Science & Technology

1997-09-30

modeled as either an effective fluid, effective viscoelastic solid, or a saturated poroelastic medium. The analysis included only the breathing mode...separated for each model . Finally, if a sediment is modeled by Biot theory, which describes wave propagation in a saturated poroelastic medium, then two...theory to sediment acoustics . The predicted resonance behavior under each model is distinct, so an optical extinction measurement may provide an

Influence of Explant Position on Growth of Talinum paniculatum Gaertn. Adventitious Root in Solid Medium and Enhance Production Biomass in Balloon Type Bubble Bioreactor

NASA Astrophysics Data System (ADS)

Solim, M. H.; Kristanti, A. N.; Manuhara, Y. S. W.

2017-03-01

Talinum paniculatum Gaertn. is one of traditional medicinal plant in Indonesia as an aphrodisiac. This plant has various compounds which is accumulated in roots. In vitro culture of this plant can enhance production of adventitious roots. The aim of this research was to know the influence of explants position on growth of T. paniculatum Gaertn. adventitious root in MS solid medium and enhance the production of biomass in balloon type bubble bioreactor. Explants from leaf were cultured at abaxial and adaxial positions in solid MS medium supplemented with IBA 2 mgL-1. Adventitious roots were cultured in bioreactor with various treatments (without IBA, supplemented with IBA 2 mgL-1 and supplemented with IBA 2 mgL-1 + buffer NaHCO3). Result showed that the main growth of abaxial root was higher than adaxial, however, the total of adaxial root branch was higher than abaxial. The highest biomass production of adventitious root cultured was achieved by MS medium supplemented with IBA 2 mgL-1 + buffer NaHCO3. This treatment has produced fresh biomass two fold of initial inoculum.

Photothermally controlled Marangoni flow around a micro bubble

NASA Astrophysics Data System (ADS)

Namura, Kyoko; Nakajima, Kaoru; Kimura, Kenji; Suzuki, Motofumi

2015-01-01

We have experimentally investigated the control of Marangoni flow around a micro bubble using photothermal conversion. Using a focused laser spot acting as a highly localized heat source on Au nanoparticles/dielectric/Ag mirror thin film enables us to create a micro bubble and to control the temperature gradient around the bubble at a micrometer scale. When we irradiate the laser next to the bubble, a strong main flow towards the bubble and two symmetric rotation flows on either side of it develop. The shape of this rotation flow shows a significant transformation depending on the relative position of the bubble and the laser spot. Using this controllable rotation flow, we have demonstrated sorting of the polystyrene spheres with diameters of 2 μm and 0.75 μm according to their size.

Tunneling effects in resonant acoustic scattering of an air bubble in unbounded water.

PubMed

Simão, André G; Guimarães, Luiz G

2016-01-01

The problem of acoustic scattering of a gaseous spherical bubble immersed within unbounded liquid surrounding is considered in this work. The theory of partial wave expansion related to this problem is revisited. A physical model based on the analogy between acoustic scattering and potential scattering in quantum mechanics is proposed to describe and interpret the acoustical natural oscillation modes of the bubble, namely, the resonances. In this context, a physical model is devised in order to describe the air water interface and the implications of the high density contrast on the various regimes of the scattering resonances. The main results are presented in terms of resonance lifetime periods and quality factors. The explicit numerical calculations are undertaken through an asymptotic analysis considering typical bubble dimensions and underwater sound wavelengths. It is shown that the resonance periods are scaled according to the Minnaert's period, which is the short lived resonance mode, called breathing mode of the bubble. As expected, resonances with longer lifetimes lead to impressive cavity quality Q-factor ranging from 1010 to 105. The present theoretical findings lead to a better understanding of the energy storage mechanism in a bubbly medium.

Models for viscosity and shear localization in bubble-rich magmas

NASA Astrophysics Data System (ADS)

Vona, Alessandro; Ryan, Amy G.; Russell, James K.; Romano, Claudia

2016-09-01

Bubble content influences magma rheology and, thus, styles of volcanic eruption. Increasing magma vesicularity affects the bulk viscosity of the bubble-melt suspension and has the potential to promote non-Newtonian behavior in the form of shear localization or brittle failure. Here, we present a series of high temperature uniaxial deformation experiments designed to investigate the effect of bubbles on the magma bulk viscosity. The starting materials are cores of natural rhyolitic obsidian synthesized to have variable vesicularity (ϕ = 0- 66%). The foamed cores were deformed isothermally (T = 750 °C) at atmospheric conditions using a high-temperature uniaxial press under constant displacement rates (strain rates between 0.5- 1 ×10-4 s-1) and to total strains of 10-40%. The viscosity of the bubble-free melt (η0) was measured by micropenetration and parallel plate methods to establish a baseline for experiments on the vesicle rich cores. At the experimental conditions, rising vesicle content produces a marked decrease in bulk viscosity that is best described by a two-parameter empirical equation: log10 ⁡ηBulk =log10 ⁡η0 - 1.47[ ϕ / (1 - ϕ) ] 0.48. Our parameterization of the bubble-melt rheology is combined with Maxwell relaxation theory to map the potential onset of non-Newtonian behavior (shear localization) in magmas as a function of melt viscosity, vesicularity, and strain rate. For low degrees of strain (i.e. as in our study), the rheological properties of vesicular magmas under different flow types (pure vs. simple shear) are indistinguishable. For high strain or strain rates where simple and pure shear viscosity values may diverge, our model represents a maximum boundary condition. Vesicular magmas can behave as non-Newtonian fluids at lower strain rates than unvesiculated melts, thereby, promoting shear localization and (explosive or non-explosive) magma fragmentation. The extent of shear localization in magma influences outgassing efficiency, thereby, affecting magma ascent and the potential for explosivity.

Extreme scattering events towards two young pulsars

NASA Astrophysics Data System (ADS)

Kerr, M.; Coles, W. A.; Ward, C. A.; Johnston, S.; Tuntsov, A. V.; Shannon, R. M.

2018-03-01

We have measured the scintillation properties of 151 young, energetic pulsars with the Parkes radio telescope and have identified two extreme scattering events (ESEs). Towards PSR J1057-5226, we discovered a 3 yr span of strengthened scattering during which the variability in flux density and the scintillation bandwidth decreased markedly. The transverse size of the scattering region is ˜23 au, and strong flux density enhancement before and after the ESE may arise from refractive focusing. Long observations reveal scintillation arcs characteristic of interference between rays scattered at large angles, and the clearest arcs appear during the ESE. The arcs suggest scattering by a screen 100-200 pc from the Earth, perhaps ionized filamentary structure associated with the boundary of the local bubble(s). Towards PSR J1740-3015, we observed a `double dip' in the measured flux density similar to ESEs observed towards compact extragalactic radio sources. The observed shape is consistent with that produced by a many-au scale diverging plasma lens with electron density ˜500 cm-3. The continuing ESE is at least 1500 d long, making it the longest detected event to date. These detections, with materially different observational signatures, indicate that well-calibrated pulsar monitoring is a keen tool for ESE detection and interstellar medium (ISM) diagnostics. They illustrate the strong role au-scale non-Kolmogorov density fluctuations and the local ISM structure play in such events and are key to understanding both their intrinsic physics and their impact on other phenomena, particularly fast radio bursts.

Impact of boundaries on velocity profiles in bubble rafts.

PubMed

Wang, Yuhong; Krishan, Kapilanjan; Dennin, Michael

2006-03-01

Under conditions of sufficiently slow flow, foams, colloids, granular matter, and various pastes have been observed to exhibit shear localization, i.e., regions of flow coexisting with regions of solidlike behavior. The details of such shear localization can vary depending on the system being studied. A number of the systems of interest are confined so as to be quasi two-dimensional, and an important issue in these systems is the role of the confining boundaries. For foams, three basic systems have been studied with very different boundary conditions: Hele-Shaw cells (bubbles confined between two solid plates); bubble rafts (a single layer of bubbles freely floating on a surface of water); and confined bubble rafts (bubbles confined between the surface of water below and a glass plate on top). Often, it is assumed that the impact of the boundaries is not significant in the "quasistatic limit," i.e., when externally imposed rates of strain are sufficiently smaller than internal kinematic relaxation times. In this paper, we directly test this assumption for rates of strain ranging from 10(-3) to 10(-2) s(-1). This corresponds to the quoted rate of strain that had been used in a number of previous experiments. It is found that the top plate dramatically alters both the velocity profile and the distribution of nonlinear rearrangements, even at these slow rates of strain. When a top is present, the flow is localized to a narrow band near the wall, and without a top, there is flow throughout the system.

Void fraction and velocity measurement of simulated bubble in a rotating disc using high frame rate neutron radiography.

PubMed

Saito, Y; Mishima, K; Matsubayashi, M

2004-10-01

To evaluate measurement error of local void fraction and velocity field in a gas-molten metal two-phase flow by high-frame-rate neutron radiography, experiments using a rotating stainless-steel disc, which has several holes of various diameters and depths simulating gas bubbles, were performed. Measured instantaneous void fraction and velocity field of the simulated bubbles were compared with the calculated values based on the rotating speed, the diameter and the depth of the holes as parameters and the measurement error was evaluated. The rotating speed was varied from 0 to 350 rpm (tangential velocity of the simulated bubbles from 0 to 1.5 m/s). The effect of shutter speed of the imaging system on the measurement error was also investigated. It was revealed from the Lagrangian time-averaged void fraction profile that the measurement error of the instantaneous void fraction depends mainly on the light-decay characteristics of the fluorescent converter. The measurement error of the instantaneous local void fraction of simulated bubbles is estimated to be 20%. In the present imaging system, the light-decay characteristics of the fluorescent converter affect the measurement remarkably, and so should be taken into account in estimating the measurement error of the local void fraction profile.

Numerical simulation of superheated vapor bubble rising in stagnant liquid

NASA Astrophysics Data System (ADS)

Samkhaniani, N.; Ansari, M. R.

2017-09-01

In present study, the rising of superheated vapor bubble in saturated liquid is simulated using volume of fluid method in OpenFOAM cfd package. The surface tension between vapor-liquid phases is considered using continuous surface force method. In order to reduce spurious current near interface, Lafaurie smoothing filter is applied to improve curvature calculation. Phase change is considered using Tanasawa mass transfer model. The variation of saturation temperature in vapor bubble with local pressure is considered with simplified Clausius-Clapeyron relation. The couple velocity-pressure equation is solved using PISO algorithm. The numerical model is validated with: (1) isothermal bubble rising and (2) one-dimensional horizontal film condensation. Then, the shape and life time history of single superheated vapor bubble are investigated. The present numerical study shows vapor bubble in saturated liquid undergoes boiling and condensation. It indicates bubble life time is nearly linear proportional with bubble size and superheat temperature.

Simulating the universe(s) III: observables for the full bubble collision spacetime

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Matthew C.; Perimeter Institute for Theoretical Physics, Waterloo, Ontario N2L 2Y5; Wainwright, Carroll L.

2016-07-14

This is the third paper in a series establishing a quantitative relation between inflationary scalar field potential landscapes and the relic perturbations left by the collision between bubbles produced during eternal inflation. We introduce a new method for computing cosmological observables from numerical relativity simulations of bubble collisions in one space and one time dimension. This method tiles comoving hypersurfaces with locally-perturbed Friedmann-Robertson-Walker coordinate patches. The method extends previous work, which was limited to the spacetime region just inside the future light cone of the collision, and allows us to explore the full bubble-collision spacetime. We validate our new methodsmore » against previous work, and present a full set of predictions for the comoving curvature perturbation and local negative spatial curvature produced by identical and non-identical bubble collisions, in single scalar field models of eternal inflation. In both collision types, there is a non-zero contribution to the spatial curvature and cosmic microwave background quadrupole. Some collisions between non-identical bubbles excite wall modes, giving extra structure to the predicted temperature anisotropies. We comment on the implications of our results for future observational searches. For non-identical bubble collisions, we also find that the surfaces of constant field can readjust in the presence of a collision to produce spatially infinite sections that become nearly homogeneous deep into the region affected by the collision. Contrary to previous assumptions, this is true even in the bubble into which the domain wall is accelerating.« less

Simulating the universe(s) III: observables for the full bubble collision spacetime

NASA Astrophysics Data System (ADS)

Johnson, Matthew C.; Wainwright, Carroll L.; Aguirre, Anthony; Peiris, Hiranya V.

2016-07-01

This is the third paper in a series establishing a quantitative relation between inflationary scalar field potential landscapes and the relic perturbations left by the collision between bubbles produced during eternal inflation. We introduce a new method for computing cosmological observables from numerical relativity simulations of bubble collisions in one space and one time dimension. This method tiles comoving hypersurfaces with locally-perturbed Friedmann-Robertson-Walker coordinate patches. The method extends previous work, which was limited to the spacetime region just inside the future light cone of the collision, and allows us to explore the full bubble-collision spacetime. We validate our new methods against previous work, and present a full set of predictions for the comoving curvature perturbation and local negative spatial curvature produced by identical and non-identical bubble collisions, in single scalar field models of eternal inflation. In both collision types, there is a non-zero contribution to the spatial curvature and cosmic microwave background quadrupole. Some collisions between non-identical bubbles excite wall modes, giving extra structure to the predicted temperature anisotropies. We comment on the implications of our results for future observational searches. For non-identical bubble collisions, we also find that the surfaces of constant field can readjust in the presence of a collision to produce spatially infinite sections that become nearly homogeneous deep into the region affected by the collision. Contrary to previous assumptions, this is true even in the bubble into which the domain wall is accelerating.

Bubble coalescence suppression driven carbon monoxide (CO)-water mass transfer increase by electrolyte addition in a hollow fiber membrane bioreactor (HFMBR) for microbial CO conversion to ethanol.

PubMed

Jang, Nulee; Yasin, Muhammad; Kang, Hyunsoo; Lee, Yeubin; Park, Gwon Woo; Park, Shinyoung; Chang, In Seop

2018-05-04

This study investigated the effects of electrolytes (CaCl 2 , K 2 HPO 4 , MgSO 4 , NaCl, and NH 4 Cl) on CO mass transfer and ethanol production in a HFMBR. The hollow fiber membranes (HFM) were found to generate tiny gas bubbles; the bubble coalescence was significantly suppressed in electrolyte solution. The volumetric gas-liquid mass transfer coefficients (k L a) increased up to 414% compared to the control. Saturated CO (C ∗ ) decreased as electrolyte concentrations increased. Overall, the maximum mass transfer rate (R max ) in electrolyte solution ranged from 106% to 339% of the value obtained in water. The electrolyte toxicity on cell growth was tested using Clostridium autoethanogenum. Most electrolytes, except for MgSO 4 , inhibited cell growth. The HFMBR operation using a medium containing 1% MgSO 4 achieved 119% ethanol production compared to that without electrolytes. Finally, a kinetic simulation using the parameters got from the 1% MgSO 4 medium predicted a higher ethanol production compared to the control. Copyright © 2018 Elsevier Ltd. All rights reserved.

Expanding Taylor bubble under constant heat flux

NASA Astrophysics Data System (ADS)

Voirand, Antoine; Benselama, Adel M.; Ayel, Vincent; Bertin, Yves

2016-09-01

Modelization of non-isothermal bubbles expanding in a capillary, as a contribution to the understanding of the physical phenomena taking place in Pulsating Heat Pipes (PHPs), is the scope of this paper. The liquid film problem is simplified and solved, while the thermal problem takes into account a constant heat flux density applied at the capillary tube wall, exchanging with the liquid film surrounding the bubble and also with the capillary tube outside medium. The liquid slug dynamics is solved using the Lucas-Washburn equation. Mass and energy balance on the vapor phase allow governing equations of bubble expansion to be written. The liquid and vapor phases are coupled only through the saturation temperature associated with the vapor pressure, assumed to be uniform throughout the bubble. Results show an over-heating of the vapor phase, although the particular thermal boundary condition used here always ensures an evaporative mass flux at the liquid-vapor interface. Global heat exchange is also investigated, showing a strong decreasing of the PHP performance to convey heat by phase change means for large meniscus velocities.

Surfactant effects on the dynamics of an intravascular bubble

NASA Astrophysics Data System (ADS)

Zhang, Jie; Eckmann, David; Ayyaswamy, P. S.

2004-11-01

The effects of a surfactant on the dynamics of gas bubble behavior in the arteriolar vasculature are numerically investigated. The equations for momentum in the bulk fluid (blood) and the bubble, and the convection-diffusion equations for mass transport both in the bulk fluid and on the gas-liquid interface are numerically solved using a front tracking method. Both soluble and insoluble surfactants are considered. The adsorption/desorption dynamics of the soluble surfactant is accurately resolved. For a nearly occluded bubble, a faster rate of depletion of the surfactant from the region adjacent to the wall of the vessel is observed. In several cases studied here, the bulk medium is treated as non-Newtonian (power law, Casson), although the majority of cases treat blood as Newtonian. Results show that the adsorbed surfactant serves to prevent blood proteins and other macromolecules from occupying the interface. This prevents clotting or adhesion of the bubble to the vessel wall. The results obtained have significance in the study of intravascular gas embolism. Supported by NIH R01 HL67986

Subsonic evolution of the radio bubbles in the nearby massive early-type galaxy NGC 4472: uplift, buoyancy, and heating

NASA Astrophysics Data System (ADS)

Kraft, Ralph P.; Gendron Marsolais, Marie-Lou; Bogdan, Akos; Su, Yuanyuan; Forman, William R.; Hlavacek-Larrondo, Julie; Jones, Christine; Nulsen, Paul; Randall, Scott W.; Roediger, Elke

2017-01-01

We present results from a deep (380 ks) Chandra observation of the hot gas in the nearby massive early-type galaxy NGC 4472. X-ray cavities were previously reported coincident with the radio lobes (Biller et al. 2004). In our deeper observation, we confirm the presence of the cavities and detect rims of enhanced emission surrounding the bubbles. The temperature of the gas in these rims is less than that of the ambient medium, demonstrating that they cold, low entropy material that has been drawn up from the group center by the buoyant rise of the bubbles and not shocks from supersonic inflation of the lobes. Interestingly, the gravitational energy required to lift these lobes from the group center is a significant fraction of the bubble enthalpy. This suggests that uplift by AGN bubbles may play an important role in some cases in offsetting the radiative cooling at cluster and group centers. This uplift also provides an efficient means of transporting enriched material from the group center to large radii.

Axisymmetric bubble pinch-off at high Reynolds numbers.

PubMed

Gordillo, J M; Sevilla, A; Rodríguez-Rodríguez, J; Martínez-Bazán, C

2005-11-04

Analytical considerations and potential-flow numerical simulations of the pinch-off of bubbles at high Reynolds numbers reveal that the bubble minimum radius, rn, decreases as tau proportional to r2n sqrt[1lnr2n], where tau is the time to break up, when the local shape of the bubble near the singularity is symmetric. However, if the gas convective terms in the momentum equation become of the order of those of the liquid, the bubble shape is no longer symmetric and the evolution of the neck changes to a rn proportional to tau1/3 power law. These findings are verified experimentally.

Nonlinear Dynamics of a Bubble Contrast Agent Oscillating near an Elastic Wall

NASA Astrophysics Data System (ADS)

Garashchuk, Ivan R.; Sinelshchikov, Dmitry I.; Kudryashov, Nikolay A.

2018-05-01

Contrast agent microbubbles, which are encapsulated gas bubbles, are widely used to enhance ultrasound imaging. There are also several new promising applications of the contrast agents such as targeted drug delivery and noninvasive therapy. Here we study three models of the microbubble dynamics: a nonencapsulated bubble oscillating close to an elastic wall, a simple coated bubble and a coated bubble near an elastic wall.We demonstrate that complex dynamics can occur in these models. We are particularly interested in the multistability phenomenon of bubble dynamics. We show that coexisting attractors appear in all of these models, but for higher acoustic pressures for the models of an encapsulated bubble.We demonstrate how several tools can be used to localize the coexisting attractors. We provide some considerations why the multistability can be undesirable for applications.

Suppression of AGN-driven Turbulence by Magnetic Fields in a Magnetohydrodynamic Model of the Intracluster Medium

NASA Astrophysics Data System (ADS)

Bambic, Christopher J.; Morsony, Brian J.; Reynolds, Christopher S.

2018-04-01

We investigate the role of active galactic nucleus (AGN) feedback in turbulent heating of galaxy clusters. Specifically, we analyze the production of turbulence by g-modes generated by the supersonic expansion and buoyant rise of AGN-driven bubbles. Previous work that neglects magnetic fields has shown that this process is inefficient, with less than 1% of the injected energy ending up in turbulence. This inefficiency primarily arises because the bubbles are shredded apart by hydrodynamic instabilities before they can excite sufficiently strong g-modes. Using a plane-parallel model of the intracluster medium (ICM) and 3D ideal magnetohydrodynamics (MHD) simulations, we examine the role of a large-scale magnetic field that is able to drape around these rising bubbles, preserving them from hydrodynamic instabilities. We find that while magnetic draping appears better able to preserve AGN-driven bubbles, the driving of g-modes and the resulting production of turbulence is still inefficient. The magnetic tension force prevents g-modes from transitioning into the nonlinear regime, suppressing turbulence in our model ICM. Our work highlights the ways in which ideal MHD is an insufficient description for the cluster feedback process, and we discuss future work such as the inclusion of anisotropic viscosity as a means of simulating high β plasma kinetic effects. These results suggest the hypothesis that other mechanisms of heating the ICM plasma such as sound waves or cosmic rays may be responsible for the observed feedback in galaxy clusters.

Drug delivery with microsecond laser pulses into gelatin

NASA Astrophysics Data System (ADS)

Shangguan, Hanqun; Casperson, Lee W.; Shearin, Alan; Gregory, Kenton W.; Prahl, Scott A.

1996-07-01

Photoacoustic drug delivery is a technique for localized drug delivery by laser-induced hydrodynamic pressure following cavitation bubble expansion and collapse. Photoacoustic drug delivery was investigated on gelatin-based thrombus models with planar and cylindrical geometries by use of one microsecond laser pulses. Solutions of a hydrophobic dye in mineral oil permitted monitoring of delivered colored oil into clear gelatin-based thrombus models. Cavitation bubble development and photoacoustic drug delivery were visualized with flash photography. This study demonstrated that cavitation is the governing mechanism for photoacoustic drug delivery, and the deepest penetration of colored oil in gels followed the bubble collapse. Spatial distribution measurements revealed that colored oil could be driven a few millimeters into the gels in both axial and radial directions, and the penetration was less than 500 mu m when the gelatin structure was not fractured. localized drug delivery, cavitation bubble, laser thrombolysis.

Groundnut shell gasification performance in a fluidized bed gasifier with bubbling air as gasification medium.

PubMed

Singh, Dharminder; Yadav, Sanjeev; Rajesh, V M; Mohanty, Pravakar

2018-05-24

This work was focused on finding the groundnut shell (GNS) gasification performance in a fluidized bed gasifier with bubbling air as gasification medium. GNS in powder form (a mixture of different particle size as given in table 8 in the article) was gasified using naturally available river sand as bed material, top of the bed feeding, conventional charcoal as bed heating medium, and two cyclones for proper cleaning and cooling the product gas. Experiments were performed using different operating conditions such as equivalence ratio (ER) between 0.29 and 0.33, bed temperature between 650°C and 800°C, and feedstock feeding rate between 36 and 31.7 kg/h. Different parameters were evaluated to study the gasifier performance such as gas yield, cold gas efficiency, carbon conversion efficiency (CCE), and high heating value. The most suitable ER value was found to be 0.31, giving the most stable bed temperature profile at 714.4°C with 5-10% fluctuation. Cold gas efficiency and CCE at optimal ER of 0.31 was found to be 71.8% and 91%, respectively.

Probing the Bioeffects of Cavitation at the Single-Cell Level

NASA Astrophysics Data System (ADS)

Yuan, Fang

The primary goal of this dissertation research is to develop an experimental system and associated techniques that can be used to investigate the bioeffects produced by cavitation bubbles at the single cell level. Such information has been lacking due to the randomness and complexity in cavitation inception and subsequent bubble-bubble interaction generated by an acoustic field typically used in therapeutic ultrasound applications. Connection between cavitation activities and bioeffects produced in cells nearby presents another challenge that has not been resolved satisfactorily. In this work, we developed a laser-based system for generating tandem bubbles with a maximum diameter about 50 microm (i.e., on the scale of a single cell) in a microfluidic channel of 25 microm in height and 800 microm in width. We further developed techniques for micropatterning of individual gold dots (15 nm thick and 6 microm in diameter) used for bubble generation, which are precisely aligned at various stand-off distances (SD) from individual islands (32 x 32 microm2) coated with fibronectin used for cell adhesion. The dynamics of tandem bubble interaction with resultant jet formation, microstreaming and vortex flow in the microfluidic channel were captured by high-speed imaging and particle image velocimetry (PIV). The deformation of the target cell was recorded by high-speed imaging as well (using a second camera) immediately after the tandem bubble interaction and assessment of membrane strain was aided with 2 microm sized polystyrene beads attached to the cell membrane. Membrane poration was characterized by uptake of fluorescent propodium iodide (PI) into the target cell, from which the normalized maximum pore size was estimated. Using this experimental system, we have observed the complete process of bubble-bubble interaction with resultant jetting flow, cell deformation, and localized pinpoint membrane rupture with progressive diffusion of macromolecules into the target cell. Furthermore, we observed a clear SD dependence in the treatment outcome produced by the tandem bubbles. At short SD of 10 microm, all treated cells underwent necrosis with high yet unsaturated level of PI uptake, indicating that the cell could not reseal the poration site. At intermediate SD of 20 ˜ 30 microm, 58% to 80% of the cells were observed to have repairable membrane poration with low to medium but saturated level of PI uptake. At long SD of 40 microm, no detectable PI uptake was observed, corresponding to no membrane compromise. Within the repairable membrane poration group, the sub-population of cells that eventually survived without apoptosis increased from about 9% at SD of 20 microm with strong adhesion to about 70% at SD of 30 microm with no adhesion at the leading edge facing the jetting flow. The maximum PI uptake, pore size, and membrane strain estimated could vary by more than an order of magnitude, which is similar to the magnitude of variations in pore size (0.2 ˜ 2 microm) produced by tandem bubbles observed by SEM. The large principal strain (> 500%) with associated high strain-rate (> 106·s -1) produced by the tandem bubbles provide a unique tool to examine the bioeffects of cavitation at the single cell level and potentially a diverse range of applications to be explored.

Determination of surface tension from the measurement of internal pressure of mini soap bubbles

NASA Astrophysics Data System (ADS)

Behroozi, F.; Behroozi, P. S.

2011-11-01

We review the elementary theory that gives the internal pressure of a soap bubble in terms of its radius and surface tension. The theory is generalized to relate the pressure difference across any element of a soap film to its local curvature. This result is used to introduce the concept of the mean curvature of a surface element and is applied to a double soap bubble to obtain the relation between the three radii that characterize its geometry. We also describe a simple setup, suitable for the undergraduate laboratory, to produce mini bubbles and to obtain the surface tension of the soap solution by measuring the radius and internal pressure of the bubbles.

Dynamics of Magnetized Plasma Jets and Bubbles Launched into a Background Magnetized Plasma

NASA Astrophysics Data System (ADS)

Wallace, B.; Zhang, Y.; Fisher, D. M.; Gilmore, M.

2016-10-01

The propagation of dense magnetized plasma, either collimated with mainly azimuthal B-field (jet) or toroidal with closed B-field (bubble), in a background plasma occurs in a number of solar and astrophysical cases. Such cases include coronal mass ejections moving in the background solar wind and extragalactic radio lobes expanding into the extragalactic medium. Understanding the detailed MHD behavior is crucial for correctly modeling these events. In order to further the understanding of such systems, we are investigating the injection of dense magnetized jets and bubbles into a lower density background magnetized plasma using a coaxial plasma gun and a background helicon or cathode plasma. In both jet and bubble cases, the MHD dynamics are found to be very different when launched into background plasma or magnetic field, as compared to vacuum. In the jet case, it is found that the inherent kink instability is stabilized by velocity shear developed due to added magnetic tension from the background field. In the bubble case, rather than directly relaxing to a minimum energy Taylor state (spheromak) as in vacuum, there is an expansion asymmetry and the bubble becomes Rayleigh-Taylor unstable on one side. Recent results will be presented. Work supported by the Army Research Office Award No. W911NF1510480.

Numerical modeling of bubble dynamics in viscoelastic media with relaxation

NASA Astrophysics Data System (ADS)

Warnez, M. T.; Johnsen, E.

2015-06-01

Cavitation occurs in a variety of non-Newtonian fluids and viscoelastic materials. The large-amplitude volumetric oscillations of cavitation bubbles give rise to high temperatures and pressures at collapse, as well as induce large and rapid deformation of the surroundings. In this work, we develop a comprehensive numerical framework for spherical bubble dynamics in isotropic media obeying a wide range of viscoelastic constitutive relationships. Our numerical approach solves the compressible Keller-Miksis equation with full thermal effects (inside and outside the bubble) when coupled to a highly generalized constitutive relationship (which allows Newtonian, Kelvin-Voigt, Zener, linear Maxwell, upper-convected Maxwell, Jeffreys, Oldroyd-B, Giesekus, and Phan-Thien-Tanner models). For the latter two models, partial differential equations (PDEs) must be solved in the surrounding medium; for the remaining models, we show that the PDEs can be reduced to ordinary differential equations. To solve the general constitutive PDEs, we present a Chebyshev spectral collocation method, which is robust even for violent collapse. Combining this numerical approach with theoretical analysis, we simulate bubble dynamics in various viscoelastic media to determine the impact of relaxation time, a constitutive parameter, on the associated physics. Relaxation time is found to increase bubble growth and permit rebounds driven purely by residual stresses in the surroundings. Different regimes of oscillations occur depending on the relaxation time.

Comment on "The night when the auroral and equatorial ionospheres converged" by Martinis, C., J. Baumgardner, M. Mendillo, J. Wroten, A. Coster, and L. Paxton

NASA Astrophysics Data System (ADS)

Kil, Hyosub; Miller, Ethan S.; Jee, Geonhwa; Kwak, Young-Sil; Zhang, Yongliang; Nishioka, Michi

2016-10-01

Intense OI 630.0 nm emission depletions were detected over Mexico by an all-sky imager during the main phase of the geomagnetic storm on 1 June 2013 (minimum Dst index: -119 nT). Those emission depletions were interpreted to be associated with equatorial plasma bubbles. If bubbles were responsible for those middle-latitude emission depletions, they would have been extreme bubbles which extended over 40° magnetic latitudes and 7000 km in altitude at the magnetic equator. However, a few factors challenge this interpretation. First, the emission depletions detected over Mexico showed westward drift, whereas the equatorial ionosphere including bubbles drifted eastward on that night. Second, the middle-latitude emission depletions were tilted westward with respect to the geographic meridian, but the westward tilt of bubbles was not identified. Third, the growth of bubbles was not evident when the middle-latitude emission depletions grew. The westward tilt and westward propagation of the middle-latitude emission depletions are consistent with the characteristics of medium-scale traveling ionospheric disturbances (MSTIDs) observed over the United States on that night. Thus, the emission depletions over Mexico can be interpreted to be the signature of MSTIDs.

Gas depletion through single gas bubble diffusive growth and its effect on subsequent bubbles

NASA Astrophysics Data System (ADS)

Moreno Soto, Alvaro; Prosperetti, Andrea; Lohse, Detlef; van der Meer, Devaraj; Physics of Fluid Group Collaboration; MCEC Netherlands CenterMultiscale Catalytic Energy Conversion Collaboration

2016-11-01

In weakly supersaturated mixtures, bubbles are known to grow quasi-statically as diffusion-driven mass transfer governs the process. In the final stage of the evolution, before detachment, there is an enhancement of mass transfer, which changes from diffusion to natural convection. Once the bubble detaches, it leaves behind a gas-depleted area. The diffusive mass transfer towards that region cannot compensate for the amount of gas which is taken away by the bubble. Consequently, the consecutive bubble will grow in an environment which contains less gas than for the previous one. This reduces the local supersaturation of the mixture around the nucleation site, leading to a reduced bubble growth rate. We present quantitative experimental data on this effect and the theoretical model for depletion during the bubble growth rate. This work was supported by the Netherlands Center for Multiscale Catalytic Energy Conversion (MCEC), an NWO Gravitation programme funded by the Ministry of Education, Culture and Science of the government of the Netherlands.

Numerical study of wall effects on buoyant gas-bubble rise in a liquid-filled finite cylinder

PubMed Central

Mukundakrishnan, Karthik; Quan, Shaoping; Eckmann, David M.; Ayyaswamy, Portonovo S.

2009-01-01

The wall effects on the axisymmetric rise and deformation of an initially spherical gas bubble released from rest in a liquid-filled, finite circular cylinder are numerically investigated. The bulk and gas phases are considered incompressible and immiscible. The bubble motion and deformation are characterized by the Morton number (Mo), Eötvös number (Eo), Reynolds number (Re), Weber number (We), density ratio, viscosity ratio, the ratios of the cylinder height and the cylinder radius to the diameter of the initially spherical bubble (H* = H/d0, R* = R/d0). Bubble rise in liquids described by Eo and Mo combinations ranging from (1,0.01) to (277.5,0.092), as appropriate to various terminal state Reynolds numbers (ReT) and shapes have been studied. The range of terminal state Reynolds numbers includes 0.02 < ReT < 70. Bubble shapes at terminal states vary from spherical to intermediate spherical-cap–skirted. The numerical procedure employs a front tracking finite difference method coupled with a level contour reconstruction of the front. This procedure ensures a smooth distribution of the front points and conserves the bubble volume. For the wide range of Eo and Mo examined, bubble motion in cylinders of height H* = 8 and R* ≥ 3, is noted to correspond to the rise in an infinite medium, both in terms of Reynolds number and shape at terminal state. In a thin cylindrical vessel (small R*), the motion of the bubble is retarded due to increased total drag and the bubble achieves terminal conditions within a short distance from release. The wake effects on bubble rise are reduced, and elongated bubbles may occur at appropriate conditions. For a fixed volume of the bubble, increasing the cylinder radius may result in the formation of well-defined rear recirculatory wakes that are associated with lateral bulging and skirt formation. The paper includes figures of bubble shape regimes for various values of R*, Eo, Mo, and ReT. Our predictions agree with existing results reported in the literature. PMID:17930342

Self-organization of cosmic radiation pressure instability

NASA Technical Reports Server (NTRS)

Hogan, Craig J.

1991-01-01

Under some circumstances the absorption of radiation momentum by an absorbing medium opens the possibility of a dynamical instability, sometimes called 'mock gravity'. Here, a simplified abstract model is studied in which the radiation source is assumed to remain spatially uniform, there is no reabsorption or reradiated light, and no forces other than radiative pressure act on the absorbing medium. It is shown that this model displays the unique feature of being not only unstable, but also self-organizing. The structure approaches a statistical dynamical steady state which is almost independent of initial conditions. In this saturated state the absorbers are concentrated in thin walls around empty bubbles; as the instability develops the big bubbles get bigger and the small ones get crushed and disappear. A linear analysis shows that to first order the thin walls are indeed stable structures. It is speculated that this instability may play a role in forming cosmic large-scale structure.

Confinement and diffusion time-scales of CR hadrons in AGN-inflated bubbles

NASA Astrophysics Data System (ADS)

Prokhorov, D. A.; Churazov, E. M.

2017-09-01

While rich clusters are powerful sources of X-rays, γ-ray emission from these large cosmic structures has not been detected yet. X-ray radiative energy losses in the central regions of relaxed galaxy clusters are so strong that one needs to consider special sources of energy, likely active galactic nucleus (AGN) feedback, to suppress catastrophic cooling of the gas. We consider a model of AGN feedback that postulates that the AGN supplies the energy to the gas by inflating bubbles of relativistic plasma, whose energy content is dominated by cosmic-ray (CR) hadrons. If most of these hadrons can quickly escape the bubbles, then collisions of CRs with thermal protons in the intracluster medium (ICM) should lead to strong γ-ray emission, unless fast diffusion of CRs removes them from the cluster. Therefore, the lack of detections with modern γ-ray telescopes sets limits on the confinement time of CR hadrons in bubbles and CR diffusive propagation in the ICM.

Elutriation characteristics of fine particles from bubbling fluidized bed incineration for sludge cake treatment.

PubMed

Chang, Yu-Min; Chou, Chih-Mei; Su, Kuo-Tung; Hung, Chao-Yang; Wu, Chao-Hsiung

2005-01-01

In this study, measurements of elutriation rate were carried out in a bench scale bubbling fluidized bed incinerator, which was used to combust sludge cake. The particle size distribution and ignition loss were analyzed to study the elutriation characteristics of bubbling fluidized bed incineration. Drawn from the experimental data, the elutriation rate constant K(i)* for fine particles were obtained and correlated with parameters. It was found that most of the solid particles (about 95%) elutriated came from the fluidized medium (inorganic matters), but few came from unburned carbon particles or soot (about 5%). Finally, this paper lists a comparison of K(i)* between this study and the published prediction equations derived or studied in non-incineration modes of fluidized bed. A new and modified correlation is proposed here to estimate the elutriation rate of fine particles emitted from a bubbling fluidized bed incinerator. Primary operation variables (superficial gas velocity and incineration temperature) affecting the elutriation rate are also discussed in the paper.

Dynamics of supernova driven superbubbles

NASA Astrophysics Data System (ADS)

Yadav, Naveen; Mukherjee, Dipanjan; Sharma, Prateek; Nath, Biman

2015-08-01

Energy injection by supernovae is believed to be one of the primary sources which powers the expansion of supershells. There is a qualitative difference between isolated supernovae (SNe) and overlapping SNe. For typical interstellar medium (ISM) conditions an isolated supernova loses most of the injected mechanical energy by 1 Myr. In contrast, for SNe going off in bubbles the radiative losses are much smaller. While the outer shock going off in the dense ISM (~1 cm-3) becomes radiative well before 1 Myr, there is a strong non-radiative termination shock that keeps the bubble over-pressured till the lifetime of the OB association (10s of Myr; Sharma et al. 2014). This has relevance for supernova feedback in galaxy formation simulations. In our previous 1-D treatment all the SNe were assumed to occur at the same location in space. It was found that a steady wind inside the bubble (Chevalier & Clegg 1985) can occur only if the number of SNe is large (>~104) and a supernova going off inside the bubble can thermalize within the termination shock. In the present work we study the effect of SNe separated in both space and time using 3-D hydrodynamic simulations with radiative cooling. If the separation between SNe is larger than the remnant’s radius at the time it becomes radiative, SNe are in the isolated regime. The explosion energy is deposited as thermal energy in a uniform, static interstellar medium (ISM) with temperature 104 K, corresponding to the warm neutral medium. The key parameters of our idealized setup are the ISM density (ngas), the number of SNe (N★) and the spatial separation between SNe (Rcl). The shock radius when it becomes radiative depends on the ISM density and number of SNe. We obtain the critical values of the key parameters (ngas, N★, Rcl) which lead to the formation of a superbubble. e.g., at least 103 SNe are required to maintain an over-pressured bubble at 20 Myr in an ISM with 1 cm-3 similarly 102 SNe going off within a region of 100 pc in an ISM with 1 cm-3 are effectively in the isolated regime. We also compare our simulation results with observational data on superbubbles.

Massive stars: Their lives in the interstellar medium; Proceedings of the Symposium, ASP Annual Meeting, 104th, Univ. of Wisconsin, Madison, June 23-25, 1992

NASA Astrophysics Data System (ADS)

Cassinelli, Joseph P.; Churchwell, Edward B.

1993-01-01

Various papers on massive stars and their relationship to the interstellar medium are presented. Individual topics addressed include: observations of newly formed massive stars, star formation with nonthermal motions, embedded stellar clusters in H II regions, a Milky Way concordance, NH3 and H2O masers, PIGs in the Trapezium, star formation in photoevaporating molecular clouds, massive star evolution, mass loss from cool supergiant stars, massive runaway stars, CNO abundances in three A-supergiants, mass loss from late-type supergiants, OBN stars and blue supergiant supernovae, the most evolved W-R stars, X-ray variability in V444 Cygni, highly polarized stars in Cassiopeia, H I bubbles around O stars, interstellar H I LY-alpha absorption, shocked ionized gas in 30 Doradus, wind mass and energy deposition. Also discussed are: stellar wind bow shocks, O stars giant bubbles in M33, Eridanus soft X-ray enhancement, wind-blown bubbles in ejecta medium, nebulae around W-R stars, highly ionized gas in the LMC, cold ionized gas around hot H II regions, initial mass function in the outer Galaxy, late stages in SNR evolution, possible LBV in NGC 1313, old SN-pulsar association, cold bright matter near SN1987A, starbursts in the nearby universe, giant H II regions, powering the superwind in NGC 253, obscuration effects in starburst Galactic nuclei, starburst propagation in dwarf galaxies, 30 Doradus, W-R content of NGC 595 and NGC 604, Cubic Cosmic X-ray Background Experiment.

A theoretical insight into H accumulation and bubble formation by applying isotropic strain on the W-H system under a fusion environment

NASA Astrophysics Data System (ADS)

Han, Quan-Fu; Liu, Yue-Lin; Zhang, Ying; Ding, Fang; Lu, Guang-Hong

2018-04-01

The solubility and bubble formation of hydrogen (H) in tungsten (W) are crucial factors for the application of W as a plasma-facing component under a fusion environment, but the data and mechanism are presently scattered, indicating some important factors might be neglected. High-energy neutron-irradiated W inevitably causes a local strain, which may change the solubility of H in W. Here, we performed first-principles calculations to predict the H solution behaviors under isotropic strain combined with temperature effect in W and found that the H solubility in interstitial lattice can be promoted/impeded by isotropic tensile/compressive strain over the temperature range 300-1800 K. The calculated H solubility presents good agreement with the experiment. Together, our previous results of anisotropic strain, except for isotropic compression, both isotropic tension and anisotropic tension/compression enhance H solution so as to reveal an important physical implication for H accumulation and bubble formation in W: strain can enhance H solubility, resulting in the preliminary nucleation of H bubble that further causes the local strain of W lattice around H bubble, which in turn improves the H solubility at the strained region that promotes continuous growth of the H bubble via a chain-reaction effect in W. This result can also interpret the H bubble formation even if no radiation damage is produced in W exposed to low-energy H plasma.

Modelling cavitation erosion using fluid–material interaction simulations

PubMed Central

Chahine, Georges L.; Hsiao, Chao-Tsung

2015-01-01

Material deformation and pitting from cavitation bubble collapse is investigated using fluid and material dynamics and their interaction. In the fluid, a novel hybrid approach, which links a boundary element method and a compressible finite difference method, is used to capture non-spherical bubble dynamics and resulting liquid pressures efficiently and accurately. The bubble dynamics is intimately coupled with a finite-element structure model to enable fluid/structure interaction simulations. Bubble collapse loads the material with high impulsive pressures, which result from shock waves and bubble re-entrant jet direct impact on the material surface. The shock wave loading can be from the re-entrant jet impact on the opposite side of the bubble, the fast primary collapse of the bubble, and/or the collapse of the remaining bubble ring. This produces high stress waves, which propagate inside the material, cause deformation, and eventually failure. A permanent deformation or pit is formed when the local equivalent stresses exceed the material yield stress. The pressure loading depends on bubble dynamics parameters such as the size of the bubble at its maximum volume, the bubble standoff distance from the material wall and the pressure driving the bubble collapse. The effects of standoff and material type on the pressure loading and resulting pit formation are highlighted and the effects of bubble interaction on pressure loading and material deformation are preliminarily discussed. PMID:26442140

Localized Tissue Surrogate Deformation due to Controlled Single Bubble Cavitation

DTIC Science & Technology

2014-08-27

calculate liquid jet formation with collapse of an empty spherical bubble due to the high surrounding fluid pressure 18. Experimental evidence of...maximum collapse pressures over a wide range between 8 MPa 13 to 2.5 GPa 11 have also been calculated . 5 A fundamental problem in the study of...and a digital image correlation (DIC) technique was used to calculate strain fields during bubble growth and collapse. The subsequent response of the

Neutron imaging with bubble chambers for inertial confinement fusion

NASA Astrophysics Data System (ADS)

Ghilea, Marian C.

One of the main methods to obtain energy from controlled thermonuclear fusion is inertial confinement fusion (ICF), a process where nuclear fusion reactions are initiated by heating and compressing a fuel target, typically in the form of a pellet that contains deuterium and tritium, relying on the inertia of the fuel mass to provide confinement. In inertial confinement fusion experiments, it is important to distinguish failure mechanisms of the imploding capsule and unambiguously diagnose compression and hot spot formation in the fuel. Neutron imaging provides such a technique and bubble chambers are capable of generating higher resolution images than other types of neutron detectors. This thesis explores the use of a liquid bubble chamber to record high yield 14.1 MeV neutrons resulting from deuterium-tritium fusion reactions on ICF experiments. A design tool to deconvolve and reconstruct penumbral and pinhole neutron images was created, using an original ray tracing concept to simulate the neutron images. The design tool proved that misalignment and aperture fabrication errors can significantly decrease the resolution of the reconstructed neutron image. A theoretical model to describe the mechanism of bubble formation was developed. A bubble chamber for neutron imaging with Freon 115 as active medium was designed and implemented for the OMEGA laser system. High neutron yields resulting from deuterium-tritium capsule implosions were recorded. The bubble density was too low for neutron imaging on OMEGA but agreed with the model of bubble formation. The research done in here shows that bubble detectors are a promising technology for the higher neutron yields expected at National Ignition Facility (NIF).

Study on bubble column humidification and dehumidification system for coal mine wastewater treatment.

PubMed

Gao, Penghui; Zhang, Meng; Du, Yuji; Cheng, Bo; Zhang, Donghai

2018-04-01

Water is important resource for human survival and development. Coal mine wastewater (CMW) is a byproduct of the process of coal mining, which is about 7.0 × 10 10 m 3 in China in 2016. Considering coal mine wastewater includes different ingredients, a new bubble column humidification and dehumidification system is proposed for CMW treatment. The system is mainly composed of a bubble column humidification and dehumidification unit, solar collector, fan and water tank, in which air is used as a circulating medium. The system can avoid water treatment component blocking for reverse osmosis (RO) and multi effect distillation (MED) dealing with CMW, and produce water greenly. By analysis of heat and mass transfer, the effects of solar radiation, air bubble velocity and mine water temperature on water treatment production characteristics are studied. Compared with other methods, thermal energy consumption (TEC) of bubble column humidification and dehumidification (BCHD) is moderate, which is about 700 kJ/kg (powered by solar energy). The results would provide a new method for CMW treatment and insights into the efficient coal wastewater treatment, besides, it helps to identify the parameters for the technology development in mine water treatment.

Numerical simulation of seismic wave propagation from land-excited large volume air-gun source

NASA Astrophysics Data System (ADS)

Cao, W.; Zhang, W.

2017-12-01

The land-excited large volume air-gun source can be used to study regional underground structures and to detect temporal velocity changes. The air-gun source is characterized by rich low frequency energy (from bubble oscillation, 2-8Hz) and high repeatability. It can be excited in rivers, reservoirs or man-made pool. Numerical simulation of the seismic wave propagation from the air-gun source helps to understand the energy partitioning and characteristics of the waveform records at stations. However, the effective energy recorded at a distance station is from the process of bubble oscillation, which can not be approximated by a single point source. We propose a method to simulate the seismic wave propagation from the land-excited large volume air-gun source by finite difference method. The process can be divided into three parts: bubble oscillation and source coupling, solid-fluid coupling and the propagation in the solid medium. For the first part, the wavelet of the bubble oscillation can be simulated by bubble model. We use wave injection method combining the bubble wavelet with elastic wave equation to achieve the source coupling. Then, the solid-fluid boundary condition is implemented along the water bottom. And the last part is the seismic wave propagation in the solid medium, which can be readily implemented by the finite difference method. Our method can get accuracy waveform of land-excited large volume air-gun source. Based on the above forward modeling technology, we analysis the effect of the excited P wave and the energy of converted S wave due to different water shapes. We study two land-excited large volume air-gun fields, one is Binchuan in Yunnan, and the other is Hutubi in Xinjiang. The station in Binchuan, Yunnan is located in a large irregular reservoir, the waveform records have a clear S wave. Nevertheless, the station in Hutubi, Xinjiang is located in a small man-made pool, the waveform records have very weak S wave. Better understanding of the characteristics of land-excited large volume air-gun can help to better use of the air-gun source.

Interaction, coalescence, and collapse of localized patterns in a quasi-one-dimensional system of interacting particles

NASA Astrophysics Data System (ADS)

Dessup, Tommy; Coste, Christophe; Saint Jean, Michel

2017-01-01

We study the path toward equilibrium of pairs of solitary wave envelopes (bubbles) that modulate a regular zigzag pattern in an annular channel. We evidence that bubble pairs are metastable states, which spontaneously evolve toward a stable single bubble. We exhibit the concept of topological frustration of a bubble pair. A configuration is frustrated when the particles between the two bubbles are not organized in a modulated staggered row. For a nonfrustrated (NF) bubble pair configuration, the bubbles interaction is attractive, whereas it is repulsive for a frustrated (F) configuration. We describe a model of interacting solitary wave that provides all qualitative characteristics of the interaction force: It is attractive for NF systems and repulsive for F systems and decreases exponentially with the bubbles distance. Moreover, for NF systems, the bubbles come closer and eventually merge as a single bubble, in a coalescence process. We also evidence a collapse process, in which one bubble shrinks in favor of the other one, overcoming an energetic barrier in phase space. This process is relevant for both NF systems and F systems. In NF systems, the coalescence prevails at low temperature, whereas thermally activated jumps make the collapse prevail at high temperature. In F systems, the path toward equilibrium involves a collapse process regardless of the temperature.

Microbubbles and ultrasound: a bird's eye view.

PubMed

Kaul, Sanjiv

2004-01-01

Gas-filled microbubbles were initially used as ultrasound contrast agent because of their intravascular rheology, which is similar to that of red blood cells. Their transit through tissue can thus be quantified with ultrasound. More recently, these bubbles have been successfully used for molecular imaging by incorporating ligands on their surfaces that will adhere to cellular and other components within the microvasculature and can be detected by ultrasound. These bubbles have also been used for delivery of genes and drugs which can be released locally by disruption of the bubbles with high-energy ultrasound. Finally, bioeffects produced by localized ultrasound disruption of microbubbles have been shown to induce angiogenesis. This brief review will provide a bird's eye view of these applications.

Acoustic cavitation in 1-butyl-3-methylimidazolium bis(triflluoromethyl-sulfonyl)imide based ionic liquid.

PubMed

Merouani, Slimane; Hamdaoui, Oualid; Haddad, Boumediene

2018-03-01

In this work, a comparison between the temperatures/pressures within acoustic cavitation bubble in an imidazolium-based room-temperature ionic liquid (RTIL), 1-butyl-3-methylimidazolium bis(triflluoromethyl-sulfonyl)imide ([BMIM][NTf 2 ]), and in water has been made for a wide range of cavitation parameters including frequency (140-1000kHz), acoustic intensity (0.5-1Wcm -2 ), liquid temperature (20-50°C) and external static pressure (0.7-1.5atm). The used cavitation model takes into account the liquid compressibility as well as the surface tension and the viscosity of the medium. It was found that the bubble temperatures and pressures were always much higher in the ionic liquid compared to those predicted in water. The valuable effect of [BMIM][NTf 2 ] on the bubble temperature was more pronounced at higher acoustic intensity and liquid temperature and lower frequency and external static pressure. However, confrontation between the predicted and the experimental estimated temperatures in ionic liquids showed an opposite trend as the temperatures measured in some pure ionic liquids are of the same order as those observed in water. The injection of liquid droplets into cavitation bubbles, the pyrolysis of ionic liquids at the bubble-solution interface as well as the lower number of collapsing bubbles in the ionic liquid may be the responsible for the lower measured bubble temperatures in ionic liquids, as compared with water. Copyright © 2017 Elsevier B.V. All rights reserved.

A detection algorithm for scale analysis of post-sunset low-latitude plasma depletions as observed by the Swarm constellation mission

NASA Astrophysics Data System (ADS)

Kervalishvili, Guram; Stolle, Claudia; Xiong, Chao

2016-04-01

ESA's constellation mission Swarm was successfully launched on 22 November 2013. The three satellites achieved their final constellation on 17 April 2014 and since then Swarm-A and Swarm-C orbiting the Earth at about 470 km (flying side-by-side) and Swarm-B at about 520 km altitude. The satellites carry instruments to monitor the F-region electron density with a sampling frequency of 2 Hz. This paper will present a detection algorithm for low-latitude post-sunset plasma bubbles (depletions), which uses local minima and maxima to detect depletions directly from electron density readings from Swarm. Our analyses were performed in the magnetic latitude (MLat) and local time (MLT) coordinate system. The detection procedure also captures the amplitude of depletion, which is called depth in the following. The width of a bubble corresponds to the length the satellite is located inside a depletion. We discuss the global distribution of depth and width of plasma bubbles and its seasonal and local time dependence for all three Swarm satellites from April 2015 through September 2015. As expected, on global average the bubble occurrence rate is highest for combined equinoxes (Mar, Apr, Sep, and Oct) and smallest for June solstice (May, Jun, Jul, and Aug). MLT distribution of the bubble occurrence number shows a sharp increase at about 19 MLT and decreases towards post-midnight hours. Interestingly, there is an inverse relation between depth and width of bubbles as function of MLT. This is true for all seasons and for all Swarm satellites. The bubble depth (width) is decreasing (increasing) from post-sunset to post-midnight for December solstice (Jan, Feb, Nov, and Dec) and combined equinoxes with about the same amplitude values for bubbles depth (width). Therefore we suggest that at post midnight when the depletions are less steep the structures of the depletions is broader than early after sunset. However for June solstice the depletions are less deep and the bubble depth and width do not change significantly throughout the evening. Deepest depletions occur at around +/- 10° magnetic latitude that is at the inner edge of the ionisation anomaly with density maxima at around 15° MLat. Therefore, the level of background electron density does not only determine the depth of a post-sunset depletion.

Ultrasound-induced oscillations of gas bubbles in contact with gelatin gel surfaces

NASA Astrophysics Data System (ADS)

Fukui, Sosuke; Ando, Keita

2017-11-01

Ultrasound-induced dynamics of gas bubbles in the vicinity of deformable boundaries are studied experimentally, as a simplified model of sonoporation in medicine. In our experiment, 28-kHz underwater ultrasound was irradiated to a gas bubble nuclei (of radius from 60 μm to 200 μm) sitting at gel surfaces (of gelatin concentration from 6 wt% to 16 wt%) and the bubble dynamics were recorded by a high-speed camera. The repeated deformation of the gel surface was found to be in phase with volumetric oscillation of the bubble. A liquid jet, which can appear toward the collapse phase in the bubble oscillation in volume, produced localized surface deformation, which is an important observation in the context of sonoporation. We characterize the maximum displacement of the gel surface with varying the bubble nuclei radius (in comparison to the resonant radius fixed approximately at 117 μm). We also examine the phase difference between the ultrasound and the bubble dynamics under the influence of the deformable boundary. The Research Grant of Keio Leading-edge Laboratory of Science & Technology.

Damping and Amplification of Seismic Waves in Gas-Charged Magma

NASA Astrophysics Data System (ADS)

Neuberg, J. W.; Lensky, N. G.

2001-12-01

Low-frequency seismic signals are generated at the interface betweeen a solid medium and a magmatic melt. The existence of gas bubbles in the magma introduces a damping mechanism which depends mainly on the gas volume fraction and on the viscosity of the melt. However, in case of a sudden unloading (e.g. by lava dome failure) a decompressional wave propagates through the magma which becomes now supersaturated. Diffusion of gas into the bubbles leads to an exponential bubble growth which is in general frequency dependent. Such a system can be represented by a negative bulk viscosity which results in a net amplification rather than damping of the decompressional wave. Furthermore, the effects of a harmonically varying pressure on the supersaturated melt is explored, as it is caused by seismic tremor and prolongued conduit resonance.

Correction to the gas phase pressure term in the continuum model for partially saturated granular media presented by Pietruszczak and co-workers

NASA Astrophysics Data System (ADS)

Iveson, Simon M.

2003-06-01

Pietruszczak and coworkers (Internat. J. Numer. Anal. Methods Geomech. 1994; 18(2):93-105; Comput. Geotech. 1991; 12( ):55-71) have presented a continuum-based model for predicting the dynamic mechanical response of partially saturated granular media with viscous interstitial liquids. In their model they assume that the gas phase is distributed uniformly throughout the medium as discrete spherical air bubbles occupying the voids between the particles. However, their derivation of the air pressure inside these gas bubbles is inconsistent with their stated assumptions. In addition the resultant dependence of gas pressure on liquid saturation lies outside of the plausible range of possible values for discrete air bubbles. This results in an over-prediction of the average bulk modulus of the void phase. Corrected equations are presented.

Numerical modeling of bubble dynamics in viscoelastic media with relaxation

PubMed Central

Warnez, M. T.; Johnsen, E.

2015-01-01

Cavitation occurs in a variety of non-Newtonian fluids and viscoelastic materials. The large-amplitude volumetric oscillations of cavitation bubbles give rise to high temperatures and pressures at collapse, as well as induce large and rapid deformation of the surroundings. In this work, we develop a comprehensive numerical framework for spherical bubble dynamics in isotropic media obeying a wide range of viscoelastic constitutive relationships. Our numerical approach solves the compressible Keller–Miksis equation with full thermal effects (inside and outside the bubble) when coupled to a highly generalized constitutive relationship (which allows Newtonian, Kelvin–Voigt, Zener, linear Maxwell, upper-convected Maxwell, Jeffreys, Oldroyd-B, Giesekus, and Phan-Thien-Tanner models). For the latter two models, partial differential equations (PDEs) must be solved in the surrounding medium; for the remaining models, we show that the PDEs can be reduced to ordinary differential equations. To solve the general constitutive PDEs, we present a Chebyshev spectral collocation method, which is robust even for violent collapse. Combining this numerical approach with theoretical analysis, we simulate bubble dynamics in various viscoelastic media to determine the impact of relaxation time, a constitutive parameter, on the associated physics. Relaxation time is found to increase bubble growth and permit rebounds driven purely by residual stresses in the surroundings. Different regimes of oscillations occur depending on the relaxation time. PMID:26130967

Bubble pump: scalable strategy for in-plane liquid routing.

PubMed

Oskooei, Ali; Günther, Axel

2015-07-07

We present an on-chip liquid routing technique intended for application in well-based microfluidic systems that require long-term active pumping at low to medium flowrates. Our technique requires only one fluidic feature layer, one pneumatic control line and does not rely on flexible membranes and mechanical or moving parts. The presented bubble pump is therefore compatible with both elastomeric and rigid substrate materials and the associated scalable manufacturing processes. Directed liquid flow was achieved in a microchannel by an in-series configuration of two previously described "bubble gates", i.e., by gas-bubble enabled miniature gate valves. Only one time-dependent pressure signal is required and initiates at the upstream (active) bubble gate a reciprocating bubble motion. Applied at the downstream (passive) gate a time-constant gas pressure level is applied. In its rest state, the passive gate remains closed and only temporarily opens while the liquid pressure rises due to the active gate's reciprocating bubble motion. We have designed, fabricated and consistently operated our bubble pump with a variety of working liquids for >72 hours. Flow rates of 0-5.5 μl min(-1), were obtained and depended on the selected geometric dimensions, working fluids and actuation frequencies. The maximum operational pressure was 2.9 kPa-9.1 kPa and depended on the interfacial tension of the working fluids. Attainable flow rates compared favorably with those of available micropumps. We achieved flow rate enhancements of 30-100% by operating two bubble pumps in tandem and demonstrated scalability of the concept in a multi-well format with 12 individually and uniformly perfused microchannels (variation in flow rate <7%). We envision the demonstrated concept to allow for the consistent on-chip delivery of a wide range of different liquids that may even include highly reactive or moisture sensitive solutions. The presented bubble pump may provide active flow control for analytical and point-of-care diagnostic devices, as well as for microfluidic cells culture and organ-on-chip platforms.

Experimental study on bubble dynamics and wall heat transfer arising from a single nucleation site at subcooled flow boiling conditions – Part 2: Data analysis on sliding bubble characteristics and associated wall heat transfer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yooa, Junsoo; Estrada-Perez, Carlos E.; Hassan, Yassin A.

In this second of two companion papers presents an analysis of sliding bubble and wall heat transfer parameters measured during subcooled boiling in a square, vertical, upward flow channel. Bubbles were generated only from a single nucleation site for better observation of both the sliding bubbles’ characteristics and their impact on wall heat transfer through optical measurement techniques. Specific interests include: (i) bubbles departure and subsequent growth while sliding, (ii) bubbles release frequency, (iii) coalescence of sliding bubbles, (iv) sliding bubbles velocity, (v) bubbles size distribution and (vi) wall heat transfer influenced by sliding bubbles. Our results showed that slidingmore » bubbles involve two distinct growth behaviors: (i) at low mass fluxes, sliding bubbles grew fast near the nucleation site, subsequently shrank, and then grew again, (ii) as mass flux increased, however, sliding bubbles grew more steadily. The bubbles originating from the single nucleation site coalesced frequently while sliding, which showed close relation with bubbles release frequency. The sliding bubble velocity near the nucleation site consistently decreased by increasing mass flux, while the observation often became reversed as the bubbles slid downstream due to the effect of interfacial drag. The sliding bubbles moved faster than the local liquid (i.e., ur<0) at low mass flux conditions, but it became reversed as the mass flux increased. The size distribution of sliding bubbles followed Gaussian distribution well both near and far from the nucleation site. The standard deviation of bubble size varied insignificantly through sliding compared to the changes in mean bubble size. Lastly, the sliding bubbles enhanced the wall heat transfer and the effect became more noticeable as inlet subcooling/mass flux decreased or wall heat flux increased. Particularly, the sliding bubble characteristics such as bubble growth behavior observed near the nucleation site played a dominant role in determining the ultimate level of wall heat transfer enhancement within the test channel.« less

Experimental study on bubble dynamics and wall heat transfer arising from a single nucleation site at subcooled flow boiling conditions – Part 2: Data analysis on sliding bubble characteristics and associated wall heat transfer

DOE PAGES

Yooa, Junsoo; Estrada-Perez, Carlos E.; Hassan, Yassin A.

2016-04-28

In this second of two companion papers presents an analysis of sliding bubble and wall heat transfer parameters measured during subcooled boiling in a square, vertical, upward flow channel. Bubbles were generated only from a single nucleation site for better observation of both the sliding bubbles’ characteristics and their impact on wall heat transfer through optical measurement techniques. Specific interests include: (i) bubbles departure and subsequent growth while sliding, (ii) bubbles release frequency, (iii) coalescence of sliding bubbles, (iv) sliding bubbles velocity, (v) bubbles size distribution and (vi) wall heat transfer influenced by sliding bubbles. Our results showed that slidingmore » bubbles involve two distinct growth behaviors: (i) at low mass fluxes, sliding bubbles grew fast near the nucleation site, subsequently shrank, and then grew again, (ii) as mass flux increased, however, sliding bubbles grew more steadily. The bubbles originating from the single nucleation site coalesced frequently while sliding, which showed close relation with bubbles release frequency. The sliding bubble velocity near the nucleation site consistently decreased by increasing mass flux, while the observation often became reversed as the bubbles slid downstream due to the effect of interfacial drag. The sliding bubbles moved faster than the local liquid (i.e., ur<0) at low mass flux conditions, but it became reversed as the mass flux increased. The size distribution of sliding bubbles followed Gaussian distribution well both near and far from the nucleation site. The standard deviation of bubble size varied insignificantly through sliding compared to the changes in mean bubble size. Lastly, the sliding bubbles enhanced the wall heat transfer and the effect became more noticeable as inlet subcooling/mass flux decreased or wall heat flux increased. Particularly, the sliding bubble characteristics such as bubble growth behavior observed near the nucleation site played a dominant role in determining the ultimate level of wall heat transfer enhancement within the test channel.« less

A HIRES analysis of the FIR emission of supernova remnants

NASA Technical Reports Server (NTRS)

Wang, Zhong

1994-01-01

The high resolution (HiRes) algorithm has been used to analyze the far infrared emission of shocked gas and dust in supernova remnants. In the case of supernova remnant IC 443, we find a very good match between the resolved features in the deconvolved images and the emissions of shocked gas mapped in other wavelengths (lines of H2, CO, HCO+, and HI). Dust emission is also found to be surrounding hot bubbles of supernova remnants which are seen in soft X-ray maps. Optical spectroscopy on the emission of the shocked gas suggests a close correlation between the FIR color and local shock speed, which is a strong function of the ambient (preshock) gas density. These provide a potentially effective way to identify regions of strong shock interaction, and thus facilitate studies of kinematics and energetics in the interstellar medium.

A simple model of ultrasound propagation in a cavitating liquid. Part I: Theory, nonlinear attenuation and traveling wave generation.

PubMed

Louisnard, O

2012-01-01

The bubbles involved in sonochemistry and other applications of cavitation oscillate inertially. A correct estimation of the wave attenuation in such bubbly media requires a realistic estimation of the power dissipated by the oscillation of each bubble, by thermal diffusion in the gas and viscous friction in the liquid. Both quantities and calculated numerically for a single inertial bubble driven at 20 kHz, and are found to be several orders of magnitude larger than the linear prediction. Viscous dissipation is found to be the predominant cause of energy loss for bubbles small enough. Then, the classical nonlinear Caflish equations describing the propagation of acoustic waves in a bubbly liquid are recast and simplified conveniently. The main harmonic part of the sound field is found to fulfill a nonlinear Helmholtz equation, where the imaginary part of the squared wave number is directly correlated with the energy lost by a single bubble. For low acoustic driving, linear theory is recovered, but for larger drivings, namely above the Blake threshold, the attenuation coefficient is found to be more than 3 orders of magnitude larger then the linear prediction. A huge attenuation of the wave is thus expected in regions where inertial bubbles are present, which is confirmed by numerical simulations of the nonlinear Helmholtz equation in a 1D standing wave configuration. The expected strong attenuation is not only observed but furthermore, the examination of the phase between the pressure field and its gradient clearly demonstrates that a traveling wave appears in the medium. Copyright © 2011 Elsevier B.V. All rights reserved.

Lyα-emitting galaxies as a probe of reionization: large-scale bubble morphology and small-scale absorbers

NASA Astrophysics Data System (ADS)

Kakiichi, Koki; Dijkstra, Mark; Ciardi, Benedetta; Graziani, Luca

2016-12-01

The visibility of Lyα-emitting galaxies during the Epoch of Reionization is controlled by both diffuse H I patches in large-scale bubble morphology and small-scale absorbers. To investigate their impacts on Lyα transfer, we apply a novel combination of analytic modelling and cosmological hydrodynamical, radiative transfer simulations to three reionization models: (I) the `bubble' model, where only diffuse H I outside ionized bubbles is present; (II) the `web' model, where H I exists only in overdense self-shielded gas; and (III) the hybrid `web-bubble' model. The three models can explain the observed Lyα luminosity function equally well, but with very different H I fractions. This confirms a degeneracy between the ionization topology of the intergalactic medium (IGM) and the H I fraction inferred from Lyα surveys. We highlight the importance of the clustering of small-scale absorbers around galaxies. A combined analysis of the Lyα luminosity function and the Lyα fraction can break this degeneracy and provide constraints on the reionization history and its topology. Constraints can be improved by analysing the full MUV-dependent redshift evolution of the Lyα fraction of Lyman break galaxies. We find that the IGM-transmission probability distribution function is unimodal for bubble models and bimodal in web models. Comparing our models to observations, we infer that the neutral fraction at z ˜ 7 is likely to be of the order of tens of per cent when interpreted with bubble or web-bubble models, with a conservative lower limit ˜1 per cent when interpreted with web models.

Piercing the Bubble: How Management Students Can Confront Poverty in Colombia

ERIC Educational Resources Information Center

Rosenbloom, Al; Cortes, Juan Alejandro

2008-01-01

This article describes the current relationship between management education in Colombia and the efforts of the management program at Universidad Pontificia Bolivariana (UPB) in Medellin to reduce local poverty. The article uses the metaphor of "the bubble" to illustrate how social class, family socialization, and the current UPB…

On the local relaxation of solid neon upon Rydberg excitation of a NO impurity: the role of the NO(A)-Ne interaction potential and zero-point quantum delocalization.

PubMed

Pajón-Suárez, Pedro; Rojas-Lorenzo, Germán A; Rubayo-Soneira, Jesús; Hernández-Lamoneda, Ramón; Larrégaray, Pascal

2009-12-31

The local relaxation of solid neon subsequent to the impulsive excitation of the NO chromophore to its A(3s sigma) Ryberg state is investigated using molecular dynamics simulations. This study makes use of empirical NO(X,A)-Ne isotropic pair potentials as well as a recently developed ab initio triatomic potential energy surface for the excited state. The role of these interaction potentials is analyzed, including many-body effects. In particular, empirical potentials, designed to reproduce correctly both the NO X-A steady-state absorption and emission bands, are shown to lead to a good description of the subpicosecond relaxation dynamics. The 600 fs expansion of the electronic bubble fairly agrees with experimental data. This relatively long time scale with respect to solid Argon, which was previously attributed to the range of the NO(A)-Ne interaction, is presumably related to the quantum nature of the medium. The time-resolved local relaxation of the Ne solid is understandably intermediate between that of classical solids (e.g., Ar) and that of quantum solids (e.g., H(2)).

What Can Be Learned from X-Ray Spectroscopy Concerning Hot Gas in the Local Bubble and Charge Exchange Processes?

NASA Technical Reports Server (NTRS)

Snowden, S. L.

2008-01-01

Both solar wind charge exchange emission and diffuse thermal emission from the Local Bubble are strongly dominated in the soft X-ray band by lines from highly ionized elements. While both processes share many of the same lines, the spectra should differ significantly due to the different production mechanisms, abundances, and ionization states. Despite their distinct spectral signatures, current and past observatories have lacked the spectral resolution to adequately distinguish between the two sources. High-resolution X-ray spectroscopy instrumentation proposed for future missions has the potential to answer fundamental questions such as whether there is any hot plasma in the Local Hot Bubble, and if so, what are the abundances of the emitting plasma and whether the plasma is in equilibrium. Such instrumentation will provide dynamic information about the solar wind including data on ion species which are currently difficult to track. It will also make possible remote sensing of the solar wind.

The 10 to the 8th power bit solid state spacecraft data recorder. [utilizing bubble domain memory technology

NASA Technical Reports Server (NTRS)

Murray, G. W.; Bohning, O. D.; Kinoshita, R. Y.; Becker, F. J.

1979-01-01

The results are summarized of a program to demonstrate the feasibility of Bubble Domain Memory Technology as a mass memory medium for spacecraft applications. The design, fabrication and test of a partially populated 10 to the 8th power Bit Data Recorder using 100 Kbit serial bubble memory chips is described. Design tradeoffs, design approach and performance are discussed. This effort resulted in a 10 to the 8th power bit recorder with a volume of 858.6 cu in and a weight of 47.2 pounds. The recorder is plug reconfigurable, having the capability of operating as one, two or four independent serial channel recorders or as a single sixteen bit byte parallel input recorder. Data rates up to 1.2 Mb/s in a serial mode and 2.4 Mb/s in a parallel mode may be supported. Fabrication and test of the recorder demonstrated the basic feasibility of Bubble Domain Memory technology for such applications. Test results indicate the need for improvement in memory element operating temperature range and detector performance.

DXL: A Sounding Rocket Mission for the Study of Solar Wind Charge Exchange and Local Hot Bubble X-Ray Emission

NASA Technical Reports Server (NTRS)

Galeazzi, M.; Prasai, K.; Uprety, Y.; Chiao, M.; Collier, M. R.; Koutroumpa, D.; Porter, F. S.; Snowden, S.; Cravens, T.; Robertson, I.;

Growth and Detachment of Oxygen Bubbles Induced by Gold-Catalyzed Decomposition of Hydrogen Peroxide.

PubMed

Lv, Pengyu; Le The, Hai; Eijkel, Jan; Van den Berg, Albert; Zhang, Xuehua; Lohse, Detlef

2017-09-28

Whereas bubble growth out of gas-oversatured solutions has been quite well understood, including the formation and stability of surface nanobubbles, this is not the case for bubbles forming on catalytic surfaces due to catalytic reactions , though it has important implications for gas evolution reactions and self-propulsion of micro/nanomotors fueled by bubble release. In this work we have filled this gap by experimentally and theoretically examining the growth and detachment dynamics of oxygen bubbles from hydrogen peroxide decomposition catalyzed by gold. We measured the bubble radius R ( t ) as a function of time by confocal microscopy and find R ( t ) ∝ t 1/2 . This diffusive growth behavior demonstrates that the bubbles grow from an oxygen-oversaturated environment. For several consecutive bubbles detaching from the same position in a short period of time, a well-repeated growing behavior is obtained from which we conclude the absence of noticeable depletion effect of oxygen from previous bubbles or increasing oversaturation from the gas production. In contrast, for two bubbles far apart either in space or in time, substantial discrepancies in their growth rates are observed, which we attribute to the variation in the local gas oversaturation. The current results show that the dynamical evolution of bubbles is influenced by comprehensive effects combining chemical catalysis and physical mass transfer. Finally, we find that the size of the bubbles at the moment of detachment is determined by the balance between buoyancy and surface tension and by the detailed geometry at the bubble's contact line.

IRAS 18153-1651: an H II region with a possible wind bubble blown by a young main-sequence B star

NASA Astrophysics Data System (ADS)

Gvaramadze, V. V.; Mackey, J.; Kniazev, A. Y.; Langer, N.; Chené, A.-N.; Castro, N.; Haworth, T. J.; Grebel, E. K.

2017-04-01

We report the results of spectroscopic observations and numerical modelling of the H II region IRAS 18153-1651. Our study was motivated by the discovery of an optical arc and two main-sequence stars of spectral type B1 and B3 near the centre of IRAS 18153-1651. We interpret the arc as the edge of the wind bubble (blown by the B1 star), whose brightness is enhanced by the interaction with a photoevaporation flow from a nearby molecular cloud. This interpretation implies that we deal with a unique case of a young massive star (the most massive member of a recently formed low-mass star cluster) caught just tens of thousands of years after its stellar wind has begun to blow a bubble into the surrounding dense medium. Our 2D, radiation-hydrodynamics simulations of the wind bubble and the H II region around the B1 star provide a reasonable match to observations, both in terms of morphology and absolute brightness of the optical and mid-infrared emission, and verify the young age of IRAS 18153-1651. Taken together our results strongly suggest that we have revealed the first example of a wind bubble blown by a main-sequence B star.

Mimicking bubble use in nature: propulsion of Janus particles due to hydrophobic-hydrophilic interactions.

PubMed

Pinchasik, Bat-El; Möhwald, Helmuth; Skirtach, Andre G

2014-07-09

Bubbles are widely used by animals in nature in order to fulfill important functions. They are used by animals in order to walk underwater or to stabilize themselves at the water/air interface. The main aim of this work is to imitate such phenomena, which is the essence of biomimetics. Here, bubbles are used to propel and to control the location of Janus particles in an aqueous medium. The synthesis of Janus SiO2-Ag and polystyrene-Ag (PS-Ag) particles through embedment in Parafilm is presented. The Janus particles, partially covered with catalytically active Ag nanoparticles, are redispersed in water and placed on a glass substrate. The active Ag sites are used for the splitting of H2O2 into water and oxygen. As a result, an oxygen bubble is formed on one side of the particle and promotes its propulsion. Once formed, the bubble-particle complex is stable and therefore, can be manipulated by tuning hydrophilic-hydrophobic interactions with the surface. In this way a transition between two- and three- dimensional motion is possible by changing the hydrophobicity of the substrate. Similar principles are used in nature. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Anomalous contact angle hysteresis of a captive bubble: advancing contact line pinning.

PubMed

Hong, Siang-Jie; Chang, Feng-Ming; Chou, Tung-He; Chan, Seong Heng; Sheng, Yu-Jane; Tsao, Heng-Kwong

2011-06-07

Contact angle hysteresis of a sessile drop on a substrate consists of continuous invasion of liquid phase with the advancing angle (θ(a)) and contact line pinning of liquid phase retreat until the receding angle (θ(r)) is reached. Receding pinning is generally attributed to localized defects that are more wettable than the rest of the surface. However, the defect model cannot explain advancing pinning of liquid phase invasion driven by a deflating bubble and continuous retreat of liquid phase driven by the inflating bubble. A simple thermodynamic model based on adhesion hysteresis is proposed to explain anomalous contact angle hysteresis of a captive bubble quantitatively. The adhesion model involves two solid–liquid interfacial tensions (γ(sl) > γ(sl)′). Young’s equation with γ(sl) gives the advancing angle θ(a) while that with γ(sl)′ due to surface rearrangement yields the receding angle θ(r). Our analytical analysis indicates that contact line pinning represents frustration in surface free energy, and the equilibrium shape corresponds to a nondifferential minimum instead of a local minimum. On the basis of our thermodynamic model, Surface Evolver simulations are performed to reproduce both advancing and receding behavior associated with a captive bubble on the acrylic glass.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, B.; The Peac Institute of Multiscale Sciences, Chengdu, Sichuan 610207; Wang, L.

With large-scale molecular dynamics simulations, we investigate shock response of He nanobubbles in single crystal Cu. For sufficient bubble size or internal pressure, a prismatic dislocation loop may form around a bubble in unshocked Cu. The internal He pressure helps to stabilize the bubble against plastic deformation. However, the prismatic dislocation loops may partially heal but facilitate nucleation of new shear and prismatic dislocation loops. For strong shocks, the internal pressure also impedes internal jetting, while a bubble assists local melting; a high speed jet breaks a He bubble into pieces dispersed among Cu. Near-surface He bubbles may burst andmore » form high velocity ejecta containing atoms and small fragments, while the ejecta velocities do not follow the three-dimensional Maxwell-Boltzmann distributions expected for thermal equilibrium. The biggest fragment size deceases with increasing shock strength. With a decrease in ligament thickness or an increase in He bubble size, the critical shock strength required for bubble bursting decreases, while the velocity range, space extension and average velocity component along the shock direction, increase. Small bubbles are more efficient in mass ejecting. Compared to voids and perfect single crystal Cu, He bubbles have pronounced effects on shock response including bubble/void collapse, Hugoniot elastic limit (HEL), deformation mechanisms, and surface jetting. HEL is the highest for perfect single crystal Cu with the same orientations, followed by He bubbles without pre-existing prismatic dislocation loops, and then voids. Complete void collapse and shear dislocations occur for embedded voids, as opposed to partial collapse, and shear and possibly prismatic dislocations for He bubbles. He bubbles lower the threshhold shock strength for ejecta formation, and increase ejecta velocity and ejected mass.« less

Detection and 3D representation of pulmonary air bubbles in HRCT volumes

NASA Astrophysics Data System (ADS)

Silva, Jose S.; Silva, Augusto F.; Santos, Beatriz S.; Madeira, Joaquim

2003-05-01

Bubble emphysema is a disease characterized by the presence of air bubbles within the lungs. With the purpose of identifying pulmonary air bubbles, two alternative methods were developed, using High Resolution Computer Tomography (HRCT) exams. The search volume is confined to the pulmonary volume through a previously developed pulmonary contour detection algorithm. The first detection method follows a slice by slice approach and uses selection criteria based on the Hounsfield levels, dimensions, shape and localization of the bubbles. Candidate regions that do not exhibit axial coherence along at least two sections are excluded. Intermediate sections are interpolated for a more realistic representation of lungs and bubbles. The second detection method, after the pulmonary volume delimitation, follows a fully 3D approach. A global threshold is applied to the entire lung volume returning candidate regions. 3D morphologic operators are used to remove spurious structures and to circumscribe the bubbles. Bubble representation is accomplished by two alternative methods. The first generates bubble surfaces based on the voxel volumes previously detected; the second method assumes that bubbles are approximately spherical. In order to obtain better 3D representations, fits super-quadrics to bubble volume. The fitting process is based on non-linear least squares optimization method, where a super-quadric is adapted to a regular grid of points defined on each bubble. All methods were applied to real and semi-synthetical data where artificial and randomly deformed bubbles were embedded in the interior of healthy lungs. Quantitative results regarding bubble geometric features are either similar to a priori known values used in simulation tests, or indicate clinically acceptable dimensions and locations when dealing with real data.

Droplets, Bubbles and Ultrasound Interactions.

PubMed

Shpak, Oleksandr; Verweij, Martin; de Jong, Nico; Versluis, Michel

2016-01-01

The interaction of droplets and bubbles with ultrasound has been studied extensively in the last 25 years. Microbubbles are broadly used in diagnostic and therapeutic medical applications, for instance, as ultrasound contrast agents. They have a similar size as red blood cells, and thus are able to circulate within blood vessels. Perfluorocarbon liquid droplets can be a potential new generation of microbubble agents as ultrasound can trigger their conversion into gas bubbles. Prior to activation, they are at least five times smaller in diameter than the resulting bubbles. Together with the violent nature of the phase-transition, the droplets can be used for local drug delivery, embolotherapy, HIFU enhancement and tumor imaging. Here we explain the basics of bubble dynamics, described by the Rayleigh-Plesset equation, bubble resonance frequency, damping and quality factor. We show the elegant calculation of the above characteristics for the case of small amplitude oscillations by linearizing the equations. The effect and importance of a bubble coating and effective surface tension are also discussed. We give the main characteristics of the power spectrum of bubble oscillations. Preceding bubble dynamics, ultrasound propagation is introduced. We explain the speed of sound, nonlinearity and attenuation terms. We examine bubble ultrasound scattering and how it depends on the wave-shape of the incident wave. Finally, we introduce droplet interaction with ultrasound. We elucidate the ultrasound-focusing concept within a droplets sphere, droplet shaking due to media compressibility and droplet phase-conversion dynamics.

Noise reduction by the application of an air-bubble curtain in offshore pile driving

NASA Astrophysics Data System (ADS)

Tsouvalas, A.; Metrikine, A. V.

2016-06-01

Underwater noise pollution is a by-product of marine industrial operations. In particular, the noise generated when a foundation pile is driven into the soil with an impact hammer is considered to be harmful for the aquatic species. In an attempt to reduce the ecological footprint, several noise mitigation techniques have been investigated. Among the various solutions proposed, the air-bubble curtain is often applied due to its efficacy in noise reduction. In this paper, a model is proposed for the investigation of the sound reduction during marine piling when an air-bubble curtain is placed around the pile. The model consists of the pile, the surrounding water and soil media, and the air-bubble curtain which is positioned at a certain distance from the pile surface. The solution approach is semi-analytical and is based on the dynamic sub-structuring technique and the modal decomposition method. Two main results of the paper can be distinguished. First, a new model is proposed that can be used for predictions of the noise levels in a computationally efficient manner. Second, an analysis is presented of the principal mechanisms that are responsible for the noise reduction due to the application of the air-bubble curtain in marine piling. The understanding of these mechanisms turns to be crucial for the exploitation of the maximum efficiency of the system. It is shown that the principal mechanism of noise reduction depends strongly on the frequency content of the radiated sound and the characteristics of the bubbly medium. For piles of large diameter which radiate most of the acoustic energy at relatively low frequencies, the noise reduction is mainly attributed to the mismatch of the acoustic impedances between the seawater and the bubbly layer. On the contrary, for smaller piles and when the radiated acoustic energy is concentrated at frequencies close to, or higher than, the resonance frequency of the air bubbles, the sound absorption within the bubbly layer becomes critical.

Ideas of Flat and Curved Space in History of Physics

NASA Astrophysics Data System (ADS)

Berezin, Alexander A.

2006-04-01

Since ``everything which is not prohibited is compulsory'' (assigned to Gell-Mann) we can postulate infinite flat Cartesian N-dimensional (N: any integer) space-time (ST) as embedding for any curved ST. Ergodicity raises quest of whether total number of inflationary and/or Everett bubbles (mini-verses) is finite, countably infinite (aleph-zero) or uncountably infinite (aleph-one). Are these bubbles form Gaussian distribution or form some non-random subsetting? Perhaps, communication between mini-verses (idea of D.Deutsch) can be facilitated by a kind of minimax non-local dynamics akin to Fermat principle? (Minimax Principle in Bubble Cosmology). Even such classical effects as magnetism and polarization have some non-local features. Can we go below the Planck length to perhaps Compton wavelength of our ``Hubble's bubble'' (h/Mc = 10 to minus 95 m, if M = 10 to 54 kg)? When talking about time loops and ergodicity (eternal return paradigm) is there some hysterisis in the way quantum states are accessed in ``forward'' or ``reverse'' direction? (reverse direction implies backward causality of J.Wheeler and/or Aristotelian final causation).

Origin of crashes in three US stock markets: shocks and bubbles

NASA Astrophysics Data System (ADS)

Johansen, Anders

2004-07-01

This paper presents an exclusive classification of the largest crashes in Dow Jones industrial average, SP500 and NASDAQ in the past century. Crashes are objectively defined as the top-rank filtered drawdowns (loss from the last local maximum to the next local minimum disregarding noise fluctuations), where the size of the filter is determined by the historical volatility of the index. It is shown that all crashes can be linked to either an external shock, e.g., outbreak of war, or a log-periodic power law (LPPL) bubble with an empirically well-defined complex value of the exponent. Conversely, with one sole exception all previously identified LPPL bubbles are followed by a top-rank drawdown. As a consequence, the analysis presented suggest a one-to-one correspondence between market crashes defined as top-rank filtered drawdowns on one hand and surprising news and LPPL bubbles on the other. We attribute this correspondence to the efficient market hypothesis effective on two quite different time scales depending on whether the market instability the crash represent is internally or externally generated.

Probing the Mechanical Strength of an Armored Bubble and Its Implication to Particle-Stabilized Foams

NASA Astrophysics Data System (ADS)

Taccoen, Nicolas; Lequeux, François; Gunes, Deniz Z.; Baroud, Charles N.

2016-01-01

Bubbles are dynamic objects that grow and rise or shrink and disappear, often on the scale of seconds. This conflicts with their uses in foams where they serve to modify the properties of the material in which they are embedded. Coating the bubble surface with solid particles has been demonstrated to strongly enhance the foam stability, although the mechanisms for such stabilization remain mysterious. In this paper, we reduce the problem of foam stability to the study of the behavior of a single spherical bubble coated with a monolayer of solid particles. The behavior of this armored bubble is monitored while the ambient pressure around it is varied, in order to simulate the dissolution stress resulting from the surrounding foam. We find that above a critical stress, localized dislocations appear on the armor and lead to a global loss of the mechanical stability. Once these dislocations appear, the armor is unable to prevent the dissolution of the gas into the surrounding liquid, which translates into a continued reduction of the bubble volume, even for a fixed overpressure. The observed route to the armor failure therefore begins from localized dislocations that lead to large-scale deformations of the shell until the bubble completely dissolves. The critical value of the ambient pressure that leads to the failure depends on the bubble radius, with a scaling of Δ Pcollapse∝R-1 , but does not depend on the particle diameter. These results disagree with the generally used elastic models to describe particle-covered interfaces. Instead, the experimental measurements are accounted for by an original theoretical description that equilibrates the energy gained from the gas dissolution with the capillary energy cost of displacing the individual particles. The model recovers the short-wavelength instability, the scaling of the collapse pressure with bubble radius, and the insensitivity to particle diameter. Finally, we use this new microscopic understanding to predict the aging of particle-stabilized foams, by applying classical Ostwald ripening models. We find that the smallest armored bubbles should fail, as the dissolution stress on these bubbles increases more rapidly than the armor strength. Both the experimental and theoretical results can readily be generalized to more complex particle interactions and shell structures.

Stream-wise distribution of skin-friction drag reduction on a flat plate with bubble injection

NASA Astrophysics Data System (ADS)

Qin, Shijie; Chu, Ning; Yao, Yan; Liu, Jingting; Huang, Bin; Wu, Dazhuan

2017-03-01

To investigate the stream-wise distribution of skin-friction drag reduction on a flat plate with bubble injection, both experiments and simulations of bubble drag reduction (BDR) have been conducted in this paper. Drag reductions at various flow speeds and air injection rates have been tested in cavitation tunnel experiments. Visualization of bubble flow pattern is implemented synchronously. The computational fluid dynamics (CFD) method, in the framework of Eulerian-Eulerian two fluid modeling, coupled with population balance model (PBM) is used to simulate the bubbly flow along the flat plate. A wide range of bubble sizes considering bubble breakup and coalescence is modeled based on experimental bubble distribution images. Drag and lift forces are fully modeled based on applicable closure models. Both predicted drag reductions and bubble distributions are in reasonable concordance with experimental results. Stream-wise distribution of BDR is revealed based on CFD-PBM numerical results. In particular, four distinct regions with different BDR characteristics are first identified and discussed in this study. Thresholds between regions are extracted and discussed. And it is highly necessary to fully understand the stream-wise distribution of BDR in order to establish a universal scaling law. Moreover, mechanism of stream-wise distribution of BDR is analysed based on the near-wall flow parameters. The local drag reduction is a direct result of near-wall max void fraction. And the near-wall velocity gradient modified by the presence of bubbles is considered as another important factor for bubble drag reduction.

Active Focal Zone Sharpening for High-Precision Treatment Using Histotripsy

PubMed Central

Wang, Tzu-Yin; Xu, Zhen; Hall, Timothy L.; Fowlkes, J. Brian; Roberts, William W.; Cain, Charles A.

2011-01-01

The goal of this study is to develop a focal zone sharpening strategy that produces more precise lesions for pulsed cavitational ultrasound therapy, or histotripsy. Precise and well-confined lesions were produced by locally suppressing cavitation in the periphery of the treatment focus without affecting cavitation in the center. The local suppression of cavitation was achieved using cavitation nuclei preconditioning pulses to actively control cavitation in the periphery of the focus. A 1-MHz 513-element therapeutic array was used to generate both the therapy and the nuclei preconditioning pulses. For therapy, 10-cycle bursts at 100-Hz pulse repetition frequency with P−/P+ pressure of 21/76 MPa were delivered to the geometric focus of the therapeutic array. For nuclei preconditioning, a different pulse was delivered to an annular region immediately surrounding the focus before each therapy pulse. A parametric study on the effective pressure, pulse duration, and delivery time of the preconditioning pulse was conducted in red blood cell-gel phantoms, where cavitational damage was indicated by the color change resulting from local cell lysis. Results showed that a short-duration (20 µs) preconditioning pulse at a medium pressure (P−/P+ pressure of 7.2/13.6 MPa) delivered shortly before (30 µs) the therapy pulse substantially suppressed the peripheral damage by 77 ± 13% while complete fractionation in the focal center was maintained. High-speed imaging of the bubble cloud showed a substantial decrease in the maximum width of the bubble cloud by 48 ± 24% using focal zone sharpening. Experiments in ex vivo livers confirmed that highly confined lesions were produced in real tissues as well as in the phantoms. This study demonstrated the feasibility of active focal zone sharpening using cavitation nuclei preconditioning, allowing for increased treatment precision compared with the natural focal width of the therapy transducer. PMID:21342816

Active focal zone sharpening for high-precision treatment using histotripsy.

PubMed

Wang, Tzu-Yin; Xu, Zhen; Hall, Timothy; Fowlkes, J; Roberts, William; Cain, Charles

2011-02-01

The goal of this study is to develop a focal zone sharpening strategy that produces more precise lesions for pulsed cavitational ultrasound therapy, or histotripsy. Precise and well-confined lesions were produced by locally suppressing cavitation in the periphery of the treatment focus without affecting cavitation in the center. The local suppression of cavitation was achieved using cavitation nuclei preconditioning pulses to actively control cavitation in the periphery of the focus. A 1-MHz 513-element therapeutic array was used to generate both the therapy and the nuclei preconditioning pulses. For therapy, 10-cycle bursts at 100-Hz pulse repetition frequency with P-/P+ pressure of 21/76 MPa were delivered to the geometric focus of the therapeutic array. For nuclei preconditioning, a different pulse was delivered to an annular region immediately surrounding the focus before each therapy pulse. A parametric study on the effective pressure, pulse duration, and delivery time of the preconditioning pulse was conducted in red blood cell-gel phantoms, where cavitational damage was indicated by the color change resulting from local cell lysis. Results showed that a short-duration (20 μs) preconditioning pulse at a medium pressure (P-/P+ pressure of 7.2/13.6 MPa) delivered shortly before (30 μs) the therapy pulse substantially suppressed the peripheral damage by 77 ± 13% while complete fractionation in the focal center was maintained. High-speed imaging of the bubble cloud showed a substantial decrease in the maximum width of the bubble cloud by 48 ± 24% using focal zone sharpening. Experiments in ex vivo livers confirmed that highly confined lesions were produced in real tissues as well as in the phantoms. This study demonstrated the feasibility of active focal zone sharpening using cavitation nuclei preconditioning, allowing for increased treatment precision compared with the natural focal width of the therapy transducer.

The sudden coalescene model of the boiling crisis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carrica, P.M.; Clausse, A.

1995-09-01

A local two-phase flow integral model of nucleate boiling and crisis is presented. The model is based on average balances on a control volume, yielding to a set of three nonlinear differential equations for the local void fraction, bubble number density and velocity. Boiling crisis as critical heat flux is interpreted as a dynamic transition caused by the coalescence of bubbles near the heater. The theoretical dynamic model is compared with experimental results obtained for linear power ramps in a horizontal plate heater in R-113, showing an excellent qualitative agreement.

Bubble Augmented Propulsor Mixture Flow Simulation near Choked Flow Condition

NASA Astrophysics Data System (ADS)

Choi, Jin-Keun; Hsiao, Chao-Tsung; Chahine, Georges

2013-03-01

The concept of waterjet thrust augmentation through bubble injection has been the subject of many patents and publications over the past several decades, and computational and experimental evidences of the augmentation of the jet thrust through bubble growth in the jet stream have been reported. Through our experimental studies, we have demonstrated net thrust augmentation as high as 70%for air volume fractions as high as 50%. However, in order to enable practical designs, an adequately validated modeling tool is required. In our previous numerical studies, we developed and validated a numerical code to simulate and predict the performance of a two-phase flow water jet propulsion system for low void fractions. In the present work, we extend the numerical method to handle higher void fractions to enable simulations for the high thrust augmentation conditions. At high void fractions, the speed of sound in the bubbly mixture decreases substantially and could be as low as 20 m/s, and the mixture velocity can approach the speed of sound in the medium. In this numerical study, we extend our numerical model, which is based on the two-way coupling between the mixture flow field and Lagrangian tracking of a large number of bubbles, to accommodate compressible flow regimes. Numerical methods used and the validation studies for various flow conditions in the bubble augmented propulsor will be presented. This work is supported by Office of Naval Research through contract N00014-11-C-0482 monitored by Dr. Ki-Han Kim.

Dynamics of single-bubble sonoluminescence. An alternative approach to the Rayleigh-Plesset equation

NASA Astrophysics Data System (ADS)

de Barros, Ana L. F.; Nogueira, Álvaro L. M. A.; Paschoal, Ricardo C.; Portes, Dirceu, Jr.; Rodrigues, Hilario

2018-03-01

Sonoluminescence is the phenomenon in which acoustic energy is (partially) transformed into light as a bubble of gas collapses inside a liquid medium. One particular model used to explain the motion of the bubble’s wall forced by acoustic pressure is expressed by the Rayleigh-Plesset equation, which can be obtained from the Navier-Stokes equation. In this article, we describe an alternative approach to derive the Rayleigh-Plesset equation based on Lagrangian mechanics. This work is addressed mainly to undergraduate students and teachers. It requires knowledge of calculus and of many concepts from various fields of physics at the intermediate level.

Experimental and calculative estimation of femtosecond laser induced-impulsive force in culture medium solution with motion analysis of polymer micro-beads

NASA Astrophysics Data System (ADS)

Yamakawa, Takeshi; Maruyama, Akihiro; Uedan, Hirohisa; Iino, Takanori; Hosokawa, Yoichiroh

2015-03-01

A new methodology to estimate the dynamics of femtosecond laser-induced impulsive force generated into water under microscope was developed. In this method, the position shift of the bead in water before and after the femtosecond laser irradiation was investigated experimentally and compared with motion equation assuming stress wave propagation with expansion and collapse the cavitation bubble. In the process of the comparison, parameters of force and time of the stress wave were determined. From these results, dynamics of propagations of shock and stress waves, cavitation bubble generation, and these actions to micro-objects were speculated.

In vitro study of bovine oligodendroglia.

PubMed

Fewster, M E; Blackstone, S

1975-12-01

Oligodendroglia were prepared by 'Ficoll' density gradient centrifugation from the centrum ovale of fetal and adult bovine brains. When cultivated in Rose Chambers, and provided an air bubble was included in the chamber during the cultivation, processes developed on cells around the circumference of the bubble. A sizeable air phase seems to be important for process formation in isolated bovine glial preparations. Various culture systems, media and additions to the cultures were examined for their effect on the behavior of the cultures. Fibroblast overgrowth occurred in oligodendroglial cultures from fetal brains in media supplemented with fetal bovine serum (FBS) but not in medium 199 supplemented with 2.5% FBS.

Growth and Detachment of Oxygen Bubbles Induced by Gold-Catalyzed Decomposition of Hydrogen Peroxide

PubMed Central

2017-01-01

Whereas bubble growth out of gas-oversatured solutions has been quite well understood, including the formation and stability of surface nanobubbles, this is not the case for bubbles forming on catalytic surfaces due to catalytic reactions, though it has important implications for gas evolution reactions and self-propulsion of micro/nanomotors fueled by bubble release. In this work we have filled this gap by experimentally and theoretically examining the growth and detachment dynamics of oxygen bubbles from hydrogen peroxide decomposition catalyzed by gold. We measured the bubble radius R(t) as a function of time by confocal microscopy and find R(t) ∝ t1/2. This diffusive growth behavior demonstrates that the bubbles grow from an oxygen-oversaturated environment. For several consecutive bubbles detaching from the same position in a short period of time, a well-repeated growing behavior is obtained from which we conclude the absence of noticeable depletion effect of oxygen from previous bubbles or increasing oversaturation from the gas production. In contrast, for two bubbles far apart either in space or in time, substantial discrepancies in their growth rates are observed, which we attribute to the variation in the local gas oversaturation. The current results show that the dynamical evolution of bubbles is influenced by comprehensive effects combining chemical catalysis and physical mass transfer. Finally, we find that the size of the bubbles at the moment of detachment is determined by the balance between buoyancy and surface tension and by the detailed geometry at the bubble’s contact line. PMID:28983387

SURVEY AND EVALUATION OF POROUS POLYETHYLENE MEDIA FINE BUBBLE TUBE AND DISK AERATORS

EPA Science Inventory

Historically, while alternative media materials have been employed over the years with varying degrees of success, the principal fine pore diffuser medium has been porous ceramic. In the early-to-mid-1970s, diffusers with plastic porus media were installed in secondary treatment...

Laser-generated Micro-bubbles for Molecular Delivery to Adherent Cells

NASA Astrophysics Data System (ADS)

Genc, Suzanne Lee

We examine the use of optical breakdown in aqueous media as a means to deliver molecules into live adherent cell cultures. This process, called optoinjection (OI), is affected both by the media composition and the cellular exposure to hydrodynamic stresses associated with the cavitation bubble formed by the optical breakdown process. Here we explore the possibility of performing OI using laser microbeams focused at low numerical aperture to provide conditions where OI can be performed at high-throughput. We first investigate the effect of media composition on plasma and cavitation bubble formation. We make the discovery that irradiation of minimal essential media, supports the formation of low-density plasmas (LDP) resulting in the generation of small (2--20 mum radius) cavitation bubbles. This provides gentle specific hydrodynamic perturbations to single or small groups of cells. The addition of supplemental fetal bovine serum to the medium prevents the formation LDPs and the resulting avalanche ionization generates larger (> 100 mum radius) bubbles and more violent hydrodynamic effects. Second, using high-speed photography we provide the first visualization of LDP-generated cavitation bubbles at precise offset locations relative to a boundary on which a cell monolayer can be cultured. These images depict the cellular exposure to different hydrodynamic conditions depending on the normalized offset distance (gamma = s/Rmax) and show how it affects the cellular exposure to shear stresses upon bubble expansion and different distributions of bubble energy upon collapse. Lastly, we examine the effects of pulse energy, parameters, and single vs. multiple laser exposures on the ability to deliver 3-5 kDa dextrans into adherent cells using both small (< 20 mum) and large (100mu m) radius bubbles. For single exposures, we identify several conditions under which OI can be optimized: (a) conditions where cell viability is maximized (˜90%) but optoinjection of viable cells is relatively low (˜30%) and (b) conditions where cell viability is compromised (˜80%) but where the optoinjection of viable cells is higher (˜50%). For multiple exposures in a grid pattern, we generally found reduced optoinjection efficacy but do identify conditions where we achieve injection of viable cells approaching 50%. We correlate these results to the cavitation bubble dynamics.

Sparging and agitation-induced injury of cultured animals cells: Do cell-to-bubble interactions in the bulk liquid injure cells?

PubMed

Michaels, J D; Mallik, A K; Papoutsakis, E T

1996-08-20

It has been established that the forces resulting from bubbles rupturing at the free air (gas)/liquid surface injure animal cells in agitated and/or sparged bioreactors. Although it has been suggested that bubble coalescence and breakup within agitated and sparged bioreactors (i.e., away from the free liquid surface) can be a source of cell injury as well, the evidence has been indirect. We have carried out experiments to examine this issue. The free air/liquid surface in a sparged and agitated bioractor was eliminated by completely filling the 2-L reactor and allowing sparged bubbles to escape through an outlet tube. Two identical bioreactors were run in parallel to make comparisons between cultures that were oxygenated via direct air sparging and the control culture in which silicone tubing was used for bubble-free oxygenation. Thus, cell damage from cell-to-bubble interactions due to processes (bubble coalescence and breakup) occurring in the bulk liquid could be isolated by eliminating damage due to bubbles rupturing at the free air/liquid surface of the bioreactor. We found that Chinese hamster ovary (CHO) cells grown in medium that does not contain shear-protecting additives can be agitated at rates up to 600 rpm without being damaged extensively by cell-to bubble interactions in the bulk of the bioreactor. We verified this using both batch and high-density perfusion cultures. We tested two impeller designs (pitched blade and Rushton) and found them not to affect cell damage under similar operational conditions. Sparger location (above vs. below the impeller) had no effect on cell damage at higher agitation rates but may affect the injury process at lower agitation intensities (here, below 250 rpm). In the absence of a headspace, we found less cell damage at higher agitation intensities (400 and 600 rpm), and we suggest that this nonintuitive finding derives from the important effect of bubble size and foam stability on the cell damage process. (c) 1996 John Wiley & Sons, Inc.

Low-density plasma formation in aqueous biological media using sub-nanosecond laser pulses

NASA Astrophysics Data System (ADS)

Genc, Suzanne L.; Ma, Huan; Venugopalan, Vasan

2014-08-01

We demonstrate the formation of low- and high-density plasmas in aqueous media using sub-nanosecond laser pulses delivered at low numerical aperture (NA = 0.25). We observe two distinct regimes of plasma formation in deionized water, phosphate buffered saline, Minimum Essential Medium (MEM), and MEM supplemented with phenol red. Optical breakdown is first initiated in a low-energy regime and characterized by bubble formation without plasma luminescence with threshold pulse energies in the range of Ep ≈ 4-5 μJ, depending on media formulation. The onset of this regime occurs over a very narrow interval of pulse energies and produces small bubbles (Rmax = 2-20 μm) due to a tiny conversion (η < 0.01%) of laser energy to bubble energy EB. The lack of visible plasma luminescence, sharp energy onset, and low bubble energy conversion are all hallmarks of low-density plasma (LDP) formation. At higher pulse energies (Ep = 11-20 μJ), the process transitions to a second regime characterized by plasma luminescence and large bubble formation. Bubbles formed in this regime are 1-2 orders of magnitude larger in size ( R max ≳ 100 μ m ) due to a roughly two-order-of-magnitude increase in bubble energy conversion (η ≳ 3%). These characteristics are consistent with high-density plasma formation produced by avalanche ionization and thermal runaway. Additionally, we show that supplementation of MEM with fetal bovine serum (FBS) limits optical breakdown to this high-energy regime. The ability to produce LDPs using sub-nanosecond pulses focused at low NA in a variety of cell culture media formulations without FBS can provide for cellular manipulation at high throughput with precision approaching that of femtosecond pulses delivered at high NA.

Growth and dissolution of an encapsulated contrast microbubble: effects of encapsulation permeability

PubMed Central

Sarkar, Kausik; Katiyar, Amit; Jain, Pankaj

2009-01-01

Gas diffusion from an encapsulated microbubble is modeled using an explicit linear relation for gas permeation through the encapsulation. Both the cases of single gas (air) and multiple gases (perfluorocarbon inside the bubble and air dissolved in surrounding liquid) are considered. An analytical expression for the dissolution time for an encapsulated air bubble is obtained; it showed that for small permeability the dissolution time increases linearly with decreasing permeability. A perfluorocarbon-filled contrast microbubble such as Definity was predicted to experience a transient growth due to air infusion before it dissolves in conformity with previous experimental findings. The growth phase occurs only for bubbles with a critical value of initial partial mole fraction of perfluorocarbon relative to air. With empirically obtained property values, the dissolution time of a 2.5 micron diameter (same as that of Definity) lipid coated octafluoropropane bubble with surface tension 25 mN/m predicts a lifetime of 42 minutes in an air saturated medium. The properties such as shell permeability, surface tension, relative mole fraction of octafluoropropane are varied to investigate their effects on the time scales of bubble growth and dissolution including their asymptotic scalings where appropriate. The dissolution dynamics scales with permeability, in that when the time is nondimensioanlized with permeability, curves for different permeabilities collapse on a single curve. Investigation of bubbles filled with other gases (non-octafluoropropane perfluorocarbon and sulfur hexafluoride) indicates longer dissolution time due to lower solubility and lower diffusivity for larger gas molecules. For such micron size encapsulated bubbles, lifetime of hours is possible only at extremely low surface tension (<1mN/m) or at extreme oversaturation. PMID:19616160

Flow and fracturing of viscoelastic media under diffusion-driven bubble growth: An analogue experiment for eruptive volcanic conduits

NASA Astrophysics Data System (ADS)

Taddeucci, J.; Spieler, O.; Ichihara, M.; Dingwell, D. B.; Scarlato, P.

2006-03-01

To visualize the behavior of erupting magma in volcanic conduits, we performed shock tube experiments on the ductile-brittle response of a viscoelastic medium to diffusion-driven bubble expansion. A sample of shear-thinning magma analogue is saturated by gas Ar under high pressure. On rapid decompression, Ar supersaturation causes bubbles to nucleate, grow, and coalesce in the sample, forcing it to expand, flow, and fracture. Experimental variables include saturation pressure and duration, and shape and lubrication of the flow path. Bubble growth in the experiments controls both flow and fracturing, and is consistent with physical models of magma vesiculation. Two types of fractures are observed: i) sharp fractures along the uppermost rim of the sample, and ii) fractures pervasively diffused throughout the sample. Rim fractures open when shear stress accumulates and strain rate is highest at the margin of the flow (a process already inferred from observations and models to occur in magma). Pervasive fractures originate when wall-friction retards expansion of the sample, causing pressure to build-up in the bubbles. When bubble pressure overcomes wall-friction and the tensile strength of the porous sample, fractures open with a range of morphologies. Both types of fracture open normally to flow direction, and both may heal as the flow proceeds. These experiments also illustrate how the development of pervasive fractures allows exsolving gas to escape from the sample before the generation of a permeable network via other processes, e.g., bubble coalescence. This is an observation that potentially impact the degassing of magma and the transition between explosive and effusive eruptions.

Forced convection in the wakes of sliding bubbles

NASA Astrophysics Data System (ADS)

Meehan, O'Reilly; Donnelly, B.; Persoons, T.; Nolan, K.; Murray, D. B.

2016-09-01

Both vapour and gas bubbles are known to significantly increase heat transfer rates between a heated surface and the surrounding fluid, even with no phase change. However, the complex wake structures means that the surface cooling is not fully understood. The current study uses high speed infra-red thermography to measure the surface temperature and convective heat flux enhancement associated with an air bubble sliding under an inclined surface, with a particular focus on the wake. Enhancement levels of 6 times natural convection levels are observed, along with cooling patterns consistent with a possible hairpin vortex structure interacting with the thermal boundary layer. Local regions of suppressed convective heat transfer highlight the complexity of the bubble wake in two-phase applications.

Analysis of airfoil transitional separation bubbles

NASA Technical Reports Server (NTRS)

Davis, R. L.; Carter, J. E.

1984-01-01

A previously developed local inviscid-viscous interaction technique for the analysis of airfoil transitional separation bubbles, ALESEP (Airfoil Leading Edge Separation) has been modified to utilize a more accurate windward finite difference procedure in the reversed flow region, and a natural transition/turbulence model has been incorporated for the prediction of transition within the separation bubble. Numerous calculations and experimental comparisons are presented to demonstrate the effects of the windward differencing scheme and the natural transition/turbulence model. Grid sensitivity and convergence capabilities of this inviscid-viscous interaction technique are briefly addressed. A major contribution of this report is that with the use of windward differencing, a second, counter-rotating eddy has been found to exist in the wall layer of the primary separation bubble.

Targeted Nanoparticle Thermometry: A Method to Measure Local Temperature at the Nanoscale Point Where Water Vapor Nucleation Occurs.

PubMed

Alaulamie, Arwa A; Baral, Susil; Johnson, Samuel C; Richardson, Hugh H

2017-01-01

An optical nanothermometer technique based on laser trapping, moving and targeted attaching an erbium oxide nanoparticle cluster is developed to measure the local temperature. The authors apply this new nanoscale temperature measuring technique (limited by the size of the nanoparticles) to measure the temperature of vapor nucleation in water. Vapor nucleation is observed after superheating water above the boiling point for degassed and nondegassed water. The average nucleation temperature for water without gas is 560 K but this temperature is lowered by 100 K when gas is introduced into the water. The authors are able to measure the temperature inside the bubble during bubble formation and find that the temperature inside the bubble spikes to over 1000 K because the heat source (optically-heated nanorods) is no longer connected to liquid water and heat dissipation is greatly reduced. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Microbubbles and Ultrasound: A Bird's Eye View.

PubMed Central

Kaul, Sanjiv

2004-01-01

Gas-filled microbubbles were initially used as ultrasound contrast agent because of their intravascular rheology, which is similar to that of red blood cells. Their transit through tissue can thus be quantified with ultrasound. More recently, these bubbles have been successfully used for molecular imaging by incorporating ligands on their surfaces that will adhere to cellular and other components within the microvasculature and can be detected by ultrasound. These bubbles have also been used for delivery of genes and drugs which can be released locally by disruption of the bubbles with high-energy ultrasound. Finally, bioeffects produced by localized ultrasound disruption of microbubbles have been shown to induce angiogenesis. This brief review will provide a bird's eye view of these applications. Images Fig. 1 Fig. 3 Fig. 4 Fig. 5 Fig. 6 Fig. 7 Fig. 8 Fig. 9 Fig. 10 Fig. 11 Fig. 12 PMID:17060963

Structural characteristics of the shock-induced boundary layer separation extended to the leading edge

NASA Astrophysics Data System (ADS)

Tao, Y.; Liu, W. D.; Fan, X. Q.; Zhao, Y. L.

2017-07-01

For a better understanding of the local unstart of supersonic/hypersonic inlet, a series of experiments has been conducted to investigate the shock-induced boundary layer separation extended to the leading edge. Using the nanoparticle-based planar laser scattering, we recorded the fine structures of these interactions under different conditions and paid more attention to their structural characteristics. According to their features, these interactions could be divided into four types. Specifically, Type A wave pattern is similar to the classic shock wave/turbulent boundary layer interaction, and Type B wave configuration consists of an overall Mach reflection above the large scale separation bubble. Due to the gradual decrease in the size of the separation bubble, the separation bubble was replaced by several vortices (Type C wave pattern). Besides, for Type D wave configuration which exists in the local unstart inlet, there appears to be some flow spillage around the leading edge.

Shock-initiated Combustion of a Spherical Density Inhomogeneity

NASA Astrophysics Data System (ADS)

Haehn, Nicholas; Oakley, Jason; Rothamer, David; Anderson, Mark; Ranjan, Devesh; Bonazza, Riccardo

2010-11-01

A spherical density inhomogeneity is prepared using fuel and oxidizer at a stoichiometric ratio and Xe as a diluent that increases the overall density of the bubble mixture (55% Xe, 30% H2, 15% O2). The experiments are performed in the Wisconsin Shock Tube Laboratory in a 9.2 m vertical shock tube with a 25.4 cm x 25.4 cm square cross-section. An injector is used to generate a 5 cm diameter soap film bubble filled with the combustible mixture. The injector retracts flush into the side of the tube releasing the bubble into a state of free fall. The combustible bubble is accelerated by a planar shock wave in N2 (2.0 < M < 2.8). The mismatch of acoustic impedances results in shock-focusing at the downstream pole of the bubble. The shock focusing results in localized temperatures and pressures significantly larger than nominal conditions behind a planar shock wave, resulting in auto-ignition at the focus. Planar Mie scattering and chemiluminescence are used simultaneously to visualize the bubble morphology and combustion characteristics. During the combustion phase, both the span-wise and stream-wise lengths of the bubble are seen to increase compared to the non-combustible scenario. Additionally, smaller instabilities are observed on the upstream surface, which are absent in the non-combustible bubbles.

Characterization of bubble core and cloudiness in Yb3+:Sr5(PO4)3F crystals using Micro-Raman spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cui, Y; Roy, U N; Bai, L

Ytterbium doped strontium fluoroapatite Yb{sup 3+}:Sr{sub 5}(PO{sub 4}){sub 3}F (Yb: S-FAP) crystals have been used in High Average Power Laser systems as gain medium. Growth induced defects associated with the crystal often affect their performance. In order to improve the crystal quality and its optical applications, it is imperative to understand the nature of these defects. In this study, we utilize Micro-Raman spectroscopy to characterize two common growth-induced defects: bubble core and cloudiness. We find the bubble core consist of voids and microcrystals of Yb: S-FAP. These microcrystals have very different orientation from that of the pure crystal outside themore » bubble core. In contrast to a previous report, neither Sr{sub 3}(PO{sub 4}){sub 2} nor Yb{sub 2}O{sub 3} are observed in the bubble core regions. On the other hand, the cloudy regions are made up of the host materials blended with a structural deformation along with impurities which include CaCO{sub 3}, YbPO{sub 4}, SrHPO{sub 4} and Sr{sub 2}P{sub 2}O{sub 7}. The impurities are randomly distributed in the cloudy regions. This analysis is necessary for understanding and eliminating these growth defects in Yb:S-FAP crystals.« less

Subgrid Modeling of AGN-driven Turbulence in Galaxy Clusters

NASA Astrophysics Data System (ADS)

Scannapieco, Evan; Brüggen, Marcus

2008-10-01

Hot, underdense bubbles powered by active galactic nuclei (AGNs) are likely to play a key role in halting catastrophic cooling in the centers of cool-core galaxy clusters. We present three-dimensional simulations that capture the evolution of such bubbles, using an adaptive mesh hydrodynamic code, FLASH3, to which we have added a subgrid model of turbulence and mixing. While pure hydro simulations indicate that AGN bubbles are disrupted into resolution-dependent pockets of underdense gas, proper modeling of subgrid turbulence indicates that this is a poor approximation to a turbulent cascade that continues far beyond the resolution limit. Instead, Rayleigh-Taylor instabilities act to effectively mix the heated region with its surroundings, while at the same time preserving it as a coherent structure, consistent with observations. Thus, bubbles are transformed into hot clouds of mixed material as they move outward in the hydrostatic intracluster medium (ICM), much as large airbursts lead to a distinctive "mushroom cloud" structure as they rise in the hydrostatic atmosphere of Earth. Properly capturing the evolution of such clouds has important implications for many ICM properties. In particular, it significantly changes the impact of AGNs on the distribution of entropy and metals in cool-core clusters such as Perseus.

Temperature impact on the micro structure of tungsten exposed to He irradiation in LHD

NASA Astrophysics Data System (ADS)

Bernard, Elodie; Sakamoto, Ryuichi; Tokitani, Masayuki; Masuzaki, Suguru; Hayashi, Hiromi; Yamada, Hiroshi; Yoshida, Naoaki

2017-02-01

A new temperature controlled material probe was designed for the exposure of tungsten samples to helium plasma in the LHD. Samples were exposed to estimated fluences of ∼1023 m-2 and temperatures ranging from 65 to 600 °C. Transmission Electron Microscopy analysis allowed the study of the impact of He irradiation under high temperatures on tungsten micro structure for the first time in real-plasma exposure conditions. Both dislocation loops and bubbles appeared from low to medium temperatures and saw an impressive increase of size (factor 4 to 6) most probably by coalescence as the temperature reaches 600 °C, with 500 °C appearing as a threshold for bubble growth. Annealing of the samples up to 800 C highlighted the stability of the dislocation damages formed by helium irradiation at high surface temperature, as bubbles and dislocation loops seem to conserve their characteristics. Additional studies on cross-sections showed that bubbles were formed much deeper (70-100 nm) than the heavily damaged surface layer (10-20 nm), raising concern about the impact on the material mechanical properties conservation and potential additional trapping of hydrogen isotopes.

Perfluorocarbon compounds: transmitting liquids for infrared laser tissue ablation

NASA Astrophysics Data System (ADS)

Frenz, Martin; Pratisto, Hans S.; Toth, Cynthia A.; Jansen, E. Duco; Altermatt, Hans J.; Welch, Ashley J.; Weber, Heinz P.

1996-05-01

One concern during IR-laser ablation of tissue under water is the mechanical injury that may be induced in tissue due to rapid bubble expansion and collapse or due to strong laser-induced pressure waves. The objective of this study was to evaluate the feasibility of using a liquid which is transparent to the IR-region of the spectrum in order to minimize these undesired mechanical side-effects. As transmitting medium perfluorocarbon liquid was used. Free- running Er:YAG and Ho:YAG laser pulses were delivered into the liquid via a 400 micrometers fiber. Bubble formation during the ablation process was recorded with fast flash photography while pressure transients were measured with a needle hydrophone. The effect of the surrounding material (air, water, perfluorooctane) on the tissue response of chicken breast was evaluated in vitro using histology. It was observed that a large bubble (up to 6 mm in diameter) was formed under perfluorooctane driven by the ablation products. This bubble, however, does not generate a pressure wave when collapsing. Although perfluorooctane only shows a weak absorption for infrared radiation, laser-induced thermal lensing in the liquid strongly decreases the radiant exposure and therefore the ablation efficiency.

The alveolar surface network: a new anatomy and its physiological significance.

PubMed

Scarpelli, E M

1998-08-01

It is generally held that the terminal lung unit (TLU) is an agglomeration of alveoli that opens into the branching air spaces of respiratory bronchioles, alveolar ducts, and alveolar sacs and that these structures are covered by a continuous thin liquid layer bearing a monomolecular film of surfactants at the open gas-liquid interface. The inherent structural and functional instability given TLUs by a broad liquid surface layer of this nature has been mitigated by the discovery that the TLU surface is in fact an agglomeration of bubbles, a foam (the alveolar surface network) that fills the TLU space and forms ultrathin foam films that 1) impart infrastructural stability to sustain aeration, 2) modulate circulation of surface liquid, both in series and in parallel, throughout the TLU and between TLUs and the liquid surface of conducting airways, 3) modulate surface liquid volume and exchange with interstitial liquid, and 4) sustain gas transfer between conducting airways and pulmonary capillaries throughout the respiratory cycle. The experimental evidence, from discovery to the present, is addressed in this report. Lungs were examined in thorax by stereomicroscopy immediately from the in vivo state at volumes ranging from functional residual capacity to maximal volume (Vmax). Lungs were then excised; bubble topography of all anterior and anterolateral surfaces was reaffirmed and also confirmed for all posterior and posterolateral surfaces. The following additional criteria verify the ubiquitous presence of normal intraalveolar bubbles. 1) Bubbles are absent in conducting airways. 2) Bubbles are stable and stationary in TLUs but can be moved individually by gentle microprobe pressure. 3) Adjoining bubbles move into the external medium through subpleural microincisions; there is no free gas, and vacated spaces are rendered airless. Adjacent bubbles may shift position in situ, while more distal bubbles remain stationary. 4) The position and movement of "large" bubbles identifies them as intraductal bubbles. 5) Transection of the lung reveals analogous bubble occurrence and history in central lung regions. 6) Bubbles become fixed in place and change shape when the lung is dried in air; the original shape and movement are restored when the lung is rewet. 7) All exteriorized bubbles are stable with lamellar (film) surface tension near zero. 8) Intact lungs prepared and processed by the new double-embedding technique reveal the intact TLU bubbles and bubble films. Lungs were also monitored directly by stereomicroscopy to establish their presence, transformations, and apparent function from birth through adulthood, as summarized in the following section. Intraalveolar bubbles and bubble films (the unit structures of the alveolar surface network) have been found in all mammalian species examined to date, including lambs, kids, and rabbit pups and adult mice, rats, rabbits, cats, and pigs. Rabbits were used for the definitive studies. 1) A unit bubble occupies each alveolus and branching airway of the TLU; unit bubbles in clusters correspond with alveolar clusters. 2) The appositions of unit bubble lamellae (films) form a network of liquid channels within the TLUs. The appositions are bubble to bubble (near alveolar entrances, at pores of Kohn, and between ductal bubbles), bubble to epithelial cell surface, and bubble to surface liquid of conducting airways. They rapidly form stable Newtonian black foam films (approximately 7 nm thick) under hydrodynamic conditions expected in vivo. 3) Lamellae of the foam films and bubbles tend to exclude bulk liquid and thus maintain near-zero surface tension. At the same time, the foam film formations--abetted by the constant but small retractive force of tissue recoil--stabilize unit bubble position within the network. 4) Unit bubble mobility in response to applied force increases as liquid accumulates within the network (e.g. (ABSTRACT TRUNCATED)

Radiation Backgrounds at Cosmic Dawn: X-Rays from Compact Binaries

NASA Astrophysics Data System (ADS)

Madau, Piero; Fragos, Tassos

2017-05-01

We compute the expected X-ray diffuse background and radiative feedback on the intergalactic medium (IGM) from X-ray binaries prior to and during the epoch of reionization. The cosmic evolution of compact binaries is followed using a population synthesis technique that treats separately neutron stars and black hole binaries in different spectral states and is calibrated to reproduce the observed X-ray properties of galaxies at z ≲ 4. Together with an updated empirical determination of the cosmic history of star formation, recent modeling of the stellar mass-metallicity relation, and a scheme for absorption by the IGM that accounts for the presence of ionized H II bubbles during the epoch of reionization, our detailed calculations provide refined predictions of the X-ray volume emissivity and filtered radiation background from “normal” galaxies at z ≳ 6. Radiative transfer effects modulate the background spectrum, which shows a characteristic peak between 1 and 2 keV. Because of the energy dependence of photoabsorption, soft X-ray photons are produced by local sources, while more energetic radiation arrives unattenuated from larger cosmological volumes. While the filtering of X-ray radiation through the IGM slightly increases the mean excess energy per photoionization, it also weakens the radiation intensity below 1 keV, lowering the mean photoionization and heating rates. Numerical integration of the rate and energy equations shows that the contribution of X-ray binaries to the ionization of the bulk IGM is negligible, with the electron fraction never exceeding 1%. Direct He I photoionizations are the main source of IGM heating, and the temperature of the largely neutral medium in between H II cavities increases above the temperature of the cosmic microwave background (CMB) only at z ≲ 10, when the volume filling factor of H II bubbles is already ≳0.1. Therefore, in this scenario, it is only at relatively late epochs that neutral intergalactic hydrogen may be observable in 21 cm emission against the CMB.

Radiation Backgrounds at Cosmic Dawn: X-Rays from Compact Binaries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Madau, Piero; Fragos, Tassos

We compute the expected X-ray diffuse background and radiative feedback on the intergalactic medium (IGM) from X-ray binaries prior to and during the epoch of reionization. The cosmic evolution of compact binaries is followed using a population synthesis technique that treats separately neutron stars and black hole binaries in different spectral states and is calibrated to reproduce the observed X-ray properties of galaxies at z ≲ 4. Together with an updated empirical determination of the cosmic history of star formation, recent modeling of the stellar mass–metallicity relation, and a scheme for absorption by the IGM that accounts for the presencemore » of ionized H ii bubbles during the epoch of reionization, our detailed calculations provide refined predictions of the X-ray volume emissivity and filtered radiation background from “normal” galaxies at z ≳ 6. Radiative transfer effects modulate the background spectrum, which shows a characteristic peak between 1 and 2 keV. Because of the energy dependence of photoabsorption, soft X-ray photons are produced by local sources, while more energetic radiation arrives unattenuated from larger cosmological volumes. While the filtering of X-ray radiation through the IGM slightly increases the mean excess energy per photoionization, it also weakens the radiation intensity below 1 keV, lowering the mean photoionization and heating rates. Numerical integration of the rate and energy equations shows that the contribution of X-ray binaries to the ionization of the bulk IGM is negligible, with the electron fraction never exceeding 1%. Direct He i photoionizations are the main source of IGM heating, and the temperature of the largely neutral medium in between H ii cavities increases above the temperature of the cosmic microwave background (CMB) only at z ≲ 10, when the volume filling factor of H ii bubbles is already ≳0.1. Therefore, in this scenario, it is only at relatively late epochs that neutral intergalactic hydrogen may be observable in 21 cm emission against the CMB.« less

Bubbling in unbounded coflowing liquids.

PubMed

Gañán-Calvo, Alfonso M; Herrada, Miguel A; Garstecki, Piotr

2006-03-31

An investigation of the stability of low density and viscosity fluid jets and spouts in unbounded coflowing liquids is presented. A full parametrical analysis from low to high Weber and Reynolds numbers shows that the presence of any fluid of finite density and viscosity inside the hollow jet elicits a transition from an absolute to a convective instability at a finite value of the Weber number, for any value of the Reynolds number. Below that critical value of the Weber number, the absolute character of the instability leads to local breakup, and consequently to local bubbling. Experimental data support our model.

Analysis of airfoil leading edge separation bubbles

NASA Technical Reports Server (NTRS)

Carter, J. E.; Vatsa, V. N.

1982-01-01

A local inviscid-viscous interaction technique was developed for the analysis of low speed airfoil leading edge transitional separation bubbles. In this analysis an inverse boundary layer finite difference analysis is solved iteratively with a Cauchy integral representation of the inviscid flow which is assumed to be a linear perturbation to a known global viscous airfoil analysis. Favorable comparisons with data indicate the overall validity of the present localized interaction approach. In addition numerical tests were performed to test the sensitivity of the computed results to the mesh size, limits on the Cauchy integral, and the location of the transition region.

Scaling behavior of microbubbles rising in water-saturated porous media

NASA Astrophysics Data System (ADS)

Kong, X.; Ma, Y.; Scheuermann, A.; Bringemeier, D.; Galindo-Torres, S. A.; Saar, M. O.; Li, L.

2015-12-01

Gas transport in the form of discrete microbubbles in saturated porous media is of importance in a number of processes relevant to many geo-environmental and engineering systems such as bubbling of greenhouse gases in river and sea beds, hydrocarbon gas migration in coal cleats and rock fractures, and air sparging for remediation of soil contaminated with volatile organic compounds. Under the assumption of no or minor volume expansion during gravity-driven migration, the transport of a single microbubble can be well described using various drag force models. However, not enough attention has been paid to the collective behavior of microbubbles during their ascend as a plume through the saturated porous medium, involving dynamic interactions between individual bubbles, bubbles and the ambient fluid, as well as bubbles and the solid matrix. With our quasi-2D, lab-scale microbubble migration experiments, where bubbles are continuously released from a diffuser at the bottom of a porous bed of hydrated gel beads, we establish a scaling relationship between the gas (bubble) release rate and various characteristic parameters of the bubble plume, such as plume tip velocity, plume width, and breakthrough time of the plume front. We find that the characteristic width of the bubble plume varies as a power of both the gas release rate and the bed thickness, with exponents of 0.2 and 0.4, respectively. Moreover, the characteristic breakthrough time also scales with both the gas release rate and the bed thickness with power-law exponents of -0.4 and 1.2, respectively. The mean pore-water velocity of the circulating ambient water also follows a power-law relationship with the gas release rate being an exponent of 0.6 of the gas release rate. This can be quantitatively proven using a simplified momentum exchange model together with the above power-law exponents for the bubble plume. These analyses on the experimental results are carried out on the basis of non-dimensional parameters and variables in order to explore the bubble transport mechanism in a way that is independent of the actual scale of the physical model. Our findings thus have implications for engineering processes and for fundamental research on bubble transport phenomena in porous media in general.

Bubble driven quasioscillatory translational motion of catalytic micromotors.

PubMed

Manjare, Manoj; Yang, Bo; Zhao, Y-P

2012-09-21

A new quasioscillatory translational motion has been observed for big Janus catalytic micromotors with a fast CCD camera. Such motional behavior is found to coincide with both the bubble growth and burst processes resulting from the catalytic reaction, and the competition of the two processes generates a net forward motion. Detailed physical models have been proposed to describe the above processes. It is suggested that the bubble growth process imposes a growth force moving the micromotor forward, while the burst process induces an instantaneous local pressure depression pulling the micromotor backward. The theoretic predictions are consistent with the experimental data.

Bubble Driven Quasioscillatory Translational Motion of Catalytic Micromotors

NASA Astrophysics Data System (ADS)

Manjare, Manoj; Yang, Bo; Zhao, Y.-P.

2012-09-01

A new quasioscillatory translational motion has been observed for big Janus catalytic micromotors with a fast CCD camera. Such motional behavior is found to coincide with both the bubble growth and burst processes resulting from the catalytic reaction, and the competition of the two processes generates a net forward motion. Detailed physical models have been proposed to describe the above processes. It is suggested that the bubble growth process imposes a growth force moving the micromotor forward, while the burst process induces an instantaneous local pressure depression pulling the micromotor backward. The theoretic predictions are consistent with the experimental data.

Influence of bubble size and thermal dissipation on compressive wave attenuation in liquid foams

NASA Astrophysics Data System (ADS)

Monloubou, M.; Saint-Jalmes, A.; Dollet, B.; Cantat, I.

2015-11-01

Acoustic or blast wave absorption by liquid foams is especially efficient and bubble size or liquid fraction optimization is an important challenge in this context. A resonant behavior of foams has recently been observed, but the main local dissipative process is still unknown. In this paper, we evidence the thermal origin of the dissipation, with an optimal bubble size close to the thermal boundary layer thickness. Using a shock tube, we produce typical pressure variation at time scales of the order of the millisecond, which propagates in the foam in linear and slightly nonlinear regimes.

Long-lived oscillons from asymmetric bubbles: Existence and stability

NASA Astrophysics Data System (ADS)

Adib, Artur B.; Gleiser, Marcelo; Almeida, Carlos A.

2002-10-01

The possibility that extremely long-lived, time-dependent, and localized field configurations (``oscillons'') arise during the collapse of asymmetrical bubbles in (2+1)-dimensional φ4 models is investigated. It is found that oscillons can develop from a large spectrum of elliptically deformed bubbles. Moreover, we provide numerical evidence that such oscillons are (a) circularly symmetric and (b) linearly stable against small arbitrary radial and angular perturbations. The latter is based on a dynamical approach designed to investigate the stability of nonintegrable time-dependent configurations that is capable of probing slowly growing instabilities not seen through the usual ``spectral'' method.

A Radio Study of the Seyfert Galaxy Markarian 6: Implications for Seyfert Life Cycles

NASA Astrophysics Data System (ADS)

Kharb, P.; O'Dea, C. P.; Baum, S. A.; Colbert, E. J. M.; Xu, C.

2006-11-01

We have carried out an extensive radio study with the Very Large Array on the Seyfert 1.5 galaxy Mrk 6 and imaged a spectacular radio structure in the source. The radio emission occurs on three different spatial scales: ~7.5 kpc bubbles, ~1.5 kpc bubbles lying nearly orthogonal to them, and a ~1 kpc radio jet lying orthogonal to the kiloparsec-scale bubble. To explain the complex morphology, we first consider a scenario in which the radio structures are the result of superwinds ejected by a nuclear starburst. However, recent Spitzer observations of Mrk 6 provide an upper limit to the star formation rate (SFR) of ~5.5 Msolar yr-1, an estimate much lower than the SFR of ~33 Msolar yr-1 derived assuming that the bubbles are a result of starburst winds energized by supernova explosions. Thus, a starburst alone cannot meet the energy requirements for the creation of the bubbles in Mrk 6. We then present an energetically plausible model wherein the bubbles are a result of energy deposited by the kiloparsec-scale jet as it plows into the interstellar medium. Finally, we consider a model in which the complex radio structure is a result of an episodically powered precessing jet that changes its orientation. This model is the most attractive as it can naturally explain the complex radio morphology and is consistent with the energetics, the spectral index, and the polarization structure. Radio emission in this scenario is a short-lived phenomenon in the lifetime of a Seyfert galaxy, which results from an accretion event.

An iterative fullwave simulation approach to multiple scattering in media with randomly distributed microbubbles

NASA Astrophysics Data System (ADS)

Joshi, Aditya; Lindsey, Brooks D.; Dayton, Paul A.; Pinton, Gianmarco; Muller, Marie

2017-05-01

Ultrasound contrast agents (UCA), such as microbubbles, enhance the scattering properties of blood, which is otherwise hypoechoic. The multiple scattering interactions of the acoustic field with UCA are poorly understood due to the complexity of the multiple scattering theories and the nonlinear microbubble response. The majority of bubble models describe the behavior of UCA as single, isolated microbubbles suspended in infinite medium. Multiple scattering models such as the independent scattering approximation can approximate phase velocity and attenuation for low scatterer volume fractions. However, all current models and simulation approaches only describe multiple scattering and nonlinear bubble dynamics separately. Here we present an approach that combines two existing models: (1) a full-wave model that describes nonlinear propagation and scattering interactions in a heterogeneous attenuating medium and (2) a Paul-Sarkar model that describes the nonlinear interactions between an acoustic field and microbubbles. These two models were solved numerically and combined with an iterative approach. The convergence of this combined model was explored in silico for 0.5 × 106 microbubbles ml-1, 1% and 2% bubble concentration by volume. The backscattering predicted by our modeling approach was verified experimentally with water tank measurements performed with a 128-element linear array transducer. An excellent agreement in terms of the fundamental and harmonic acoustic fields is shown. Additionally, our model correctly predicts the phase velocity and attenuation measured using through transmission and predicted by the independent scattering approximation.

Analytical study of the acoustic field in a spherical resonator for single bubble sonoluminescence.

PubMed

Dellavale, Damián; Urteaga, Raúl; Bonetto, Fabián J

2010-01-01

The acoustic field in the liquid within a spherical solid shell is calculated. The proposed model takes into account Stoke's wave equation in the viscous fluid, the membrane theory to describe the solid shell motion and the energy loss through the external couplings of the system. A point source at the resonator center is included to reproduce the acoustic emission of a sonoluminescence bubble. Particular calculations of the resulting acoustic field are performed for viscous liquids of interest in single bubble sonoluminescence. The model reveals that in case of radially symmetric modes of low frequency, the quality factor is mainly determined by the acoustic energy flowing through the mechanical coupling of the resonator. Alternatively, for high frequency modes the quality factor is mainly determined by the viscous dissipation in the liquid. Furthermore, the interaction between the bubble acoustic emission and the resonator modes is analyzed. It was found that the bubble acoustic emission produces local maxima in the resonator response. The calculated amplitudes and relative phases of the harmonics constituting the bubble acoustic environment can be used to improve multi-frequency driving in sonoluminescence.

Method for eliminating gas blocking in electrokinetic pumping systems

DOEpatents

Arnold, Don W.; Paul, Phillip H.; Schoeniger, Joseph S.

2001-09-11

A method for eliminating gas bubble blockage of current flow during operation of an electrokinetic pump. By making use of the ability to modify the surface charge on the porous dielectric medium used in electrokinetic pumps, it becomes possible to place electrodes away from the pressurized region of the electrokinetic pump. While gas is still generated at the electrodes they are situated such that the generated gas can escape into a larger buffer reservoir and not into the high pressure region of the pump where the gas bubbles can interrupt current flow. Various combinations of porous dielectric materials and ionic conductors can be used to create pumps that have desirable electrical, material handling, and flow attributes.

Maximization of organic acids production by Aspergillus niger in a bubble column bioreactor for V and Ni recovery enhancement from power plant residual ash in spent-medium bioleaching experiments.

PubMed

Rasoulnia, P; Mousavi, S M

2016-09-01

Spent-medium bioleaching of V and Ni from a power plant residual ash (PPR ash) was conducted using organic acids produced by Aspergillus niger. The production of organic acids in a bubble column bioreactor was optimized through selecting three most influencing factors. Under optimum condition of aeration rate of 762.5(ml/min), sucrose concentration of 101.9(g/l) and inoculum size of 40(ml/l), respectively 17,185, 4539, 1042 and 502(ppm) of oxalic, gluconic, citric and malic acids were produced. Leaching experiments were carried out using biogenic produced organic acids under leaching environment temperature of 60°C and rotary shaking speed of 135rpm, with various pulp densities of 1, 2, 3, 5, 7 and 9(%w/v). The results showed that biogenic produced organic acids leached V much more efficiently than Ni so that even at high pulp density of 9(%w/v), 83% of V was recovered while Ni recovery yield was 30%. Copyright © 2016 Elsevier Ltd. All rights reserved.

Stability, diffusion and interactions of nonlinear excitations in a many body system

NASA Astrophysics Data System (ADS)

Coste, Christophe; Jean, Michel Saint; Dessup, Tommy

2017-04-01

When repelling particles are confined in a quasi-one-dimensional trap by a transverse potential, a configurational phase transition happens. All particles are aligned along the trap axis at large confinement, but below a critical transverse confinement they adopt a staggered row configuration (zigzag phase). This zigzag transition is a subcritical pitchfork bifurcation in extended systems and in systems with cyclic boundary conditions in the longitudinal direction. Among many evidences, phase coexistence is exhibited by localized nonlinear patterns made of a zigzag phase embedded in otherwise aligned particles. We give the normal form at the bifurcation and we show that these patterns can be described as solitary wave envelopes that we call bubbles. They are stable in a large temperature range and can diffuse as quasi-particles, with a diffusion coefficient that may be deduced from the normal form. The potential energy of a bubble is found to be lower than that of the homogeneous bifurcated phase, which explains their stability. We observe also metastable states, that are pairs of solitary wave envelopes which spontaneously evolve toward a stable single bubble. We evidence a strong effect of the discreteness of the underlying particles system and introduce the concept of topological frustration of a bubble pair. A configuration is frustrated when the particles between the two bubbles are not organized in a modulated staggered row. For a nonfrustrated (NF) bubble pair configuration, the bubbles interaction is attractive so that the bubbles come closer and eventually merge as a single bubble. In contrast, the bubbles interaction is found to be repulsive for a frustrated (F) configuration. We describe a model of interacting solitary wave that provides all qualitative characteristics of the interaction force: it is attractive for NF-systems, repulsive for F-systems, and decreases exponentially with the bubbles distance.

Completing the evolution of supernova remnants and their bubbles

NASA Technical Reports Server (NTRS)

Slavin, Jonathan D.; Cox, Donald P.

1992-01-01

The filling fraction of hot gas in the ISM is reexamined with new calculations of the very long term evolution of SNRs and their fossil hot bubbles. Results are presented of a 1D numerical solution of the evolution of an SNR in a homogeneous medium with a nonthermal pressure corresponding to a 5-micro-G magnetic field and density of 0.2/cu cm. Comparison is made with a control simulation having no magnetic field pressure. It is found that the evolutions, once they have become radiative, differ in several significant ways, while both differ appreciably from qualitative pictures presented in the past. Over most of the evolution of either case, the hot bubble in the interior occupies only a small fraction of the shocked volume, the remainder in a thick shell of slightly compressed material. Column densities and radial distributions of O VI, N V, C IV, and Si IV as well as examples of absorption profiles for their strong UV lines are presented.

Acoustic methods for cavitation mapping in biomedical applications

NASA Astrophysics Data System (ADS)

Wan, M.; Xu, S.; Ding, T.; Hu, H.; Liu, R.; Bai, C.; Lu, S.

2015-12-01

In recent years, cavitation is increasingly utilized in a wide range of applications in biomedical field. Monitoring the spatial-temporal evolution of cavitation bubbles is of great significance for efficiency and safety in biomedical applications. In this paper, several acoustic methods for cavitation mapping proposed or modified on the basis of existing work will be presented. The proposed novel ultrasound line-by-line/plane-by-plane method can depict cavitation bubbles distribution with high spatial and temporal resolution and may be developed as a potential standard 2D/3D cavitation field mapping method. The modified ultrafast active cavitation mapping based upon plane wave transmission and reception as well as bubble wavelet and pulse inversion technique can apparently enhance the cavitation to tissue ratio in tissue and further assist in monitoring the cavitation mediated therapy with good spatial and temporal resolution. The methods presented in this paper will be a foundation to promote the research and development of cavitation imaging in non-transparent medium.

Feedback by massive stars and the emergence of superbubbles. I. Energy efficiency and Vishniac instabilities

NASA Astrophysics Data System (ADS)

Krause, M.; Fierlinger, K.; Diehl, R.; Burkert, A.; Voss, R.; Ziegler, U.

2013-02-01

Context. Massive stars influence their environment through stellar winds, ionising radiation, and supernova explosions. This is signified by observed interstellar bubbles. Such feedback is an important factor for galaxy evolution theory and galactic wind models. The efficiency of the energy injection into the interstellar medium (ISM) via bubbles and superbubbles is uncertain, and is usually treated as a free parameter for galaxy scale effects. In particular, since many stars are born in groups, it is interesting to study the dependence of the effective energy injection on the concentration of the stars. Aims: We aim to reproduce observations of superbubbles, their relation to the energy injection of the parent stars, and to understand their effective energy input into the ISM, as a function of the spatial configuration of the group of parent stars. Methods: We study the evolution of isolated and merging interstellar bubbles of three stars (25, 32, and 60 M⊙) in a homogeneous background medium with a density of 10mp cm-3 via 3D-hydrodynamic simulations with standard ISM thermodynamics (optically thin radiative cooling and photo-electric heating) and time-dependent energy and mass input according to stellar evolutionary tracks. We vary the position of the three stars relative to each other to compare the energy response for cases of isolated, merging and initially cospatial bubbles. Results: Mainly due to the Vishniac instability, our simulated bubbles develop thick shells and filamentary internal structures in column density. The shell widths reach tens of per cent of the outer bubble radius, which compares favourably to observations. More energy is retained in the ISM for more closely packed groups, by up to a factor of three and typically a factor of two for intermediate times after the first supernova. Once the superbubble is established, different positions of the contained stars make only a minor difference to the energy tracks. For our case of three massive stars, the energy deposition varies only very little for distances up to about 30 pc between the stars. Energy injected by supernovae is entirely dissipated in a superbubble on a timescale of about 1 Myr, which increases slightly with the superbubble size at the time of the explosion. Conclusions: The Vishniac instability may be responsible for the broadening of the shells of interstellar bubbles. Massive star winds are significant energetically due to their - in the long run - more efficient, steady energy injection and because they evacuate the space around the massive stars. For larger scale simulations, the feedback effect of close groups of stars or clusters may be subsumed into one effective energy input with insignificant loss of energy accuracy. The movie associated to Fig. 3 is available at http://www.aanda.org

Observations of O VI Emission from the Diffuse Interstellar Medium

NASA Technical Reports Server (NTRS)

Shelton, R. L.; Kruk, J. W.; Murphy, E. M.; Andersson, B. G.; Blair, W. P.; Dixon, W. V.; Edelstein, J.; Fullerton, A. W.; Gry, C.; Howk, J. C.;

Bubble Combustion

NASA Technical Reports Server (NTRS)

Corrigan, Jackie

2004-01-01

A method of energy production that is capable of low pollutant emissions is fundamental to one of the four pillars of NASA s Aeronautics Blueprint: Revolutionary Vehicles. Bubble combustion, a new engine technology currently being developed at Glenn Research Center promises to provide low emissions combustion in support of NASA s vision under the Emissions Element because it generates power, while minimizing the production of carbon dioxide (CO2) and nitrous oxides (NOx), both known to be Greenhouse gases. and allows the use of alternative fuels such as corn oil, low-grade fuels, and even used motor oil. Bubble combustion is analogous to the inverse of spray combustion: the difference between bubble and spray combustion is that spray combustion is spraying a liquid in to a gas to form droplets, whereas bubble combustion involves injecting a gas into a liquid to form gaseous bubbles. In bubble combustion, the process for the ignition of the bubbles takes place on a time scale of less than a nanosecond and begins with acoustic waves perturbing each bubble. This perturbation causes the local pressure to drop below the vapor pressure of the liquid thus producing cavitation in which the bubble diameter grows, and upon reversal of the oscillating pressure field, the bubble then collapses rapidly with the aid of the high surface tension forces acting on the wall of the bubble. The rapid and violent collapse causes the temperatures inside the bubbles to soar as a result of adiabatic heating. As the temperatures rise, the gaseous contents of the bubble ignite with the bubble itself serving as its own combustion chamber. After ignition, this is the time in the bubble s life cycle where power is generated, and CO2, and NOx among other species, are produced. However, the pollutants CO2 and NOx are absorbed into the surrounding liquid. The importance of bubble combustion is that it generates power using a simple and compact device. We conducted a parametric study using CAVCHEM, a computational model developed at Glenn, that simulates the cavitational collapse of a single bubble in a liquid (water) and the subsequent combustion of the gaseous contents inside the bubble. The model solves the time-dependent, compressible Navier-Stokes equations in one-dimension with finite-rate chemical kinetics using the CHEMKIN package. Specifically, parameters such as frequency, pressure, bubble radius, and the equivalence ratio were varied while examining their effect on the maximum temperature, radius, and chemical species. These studies indicate that the radius of the bubble is perhaps the most critical parameter governing bubble combustion dynamics and its efficiency. Based on the results of the parametric studies, we plan on conducting experiments to study the effect of ultrasonic perturbations on the bubble generation process with respect to the bubble radius and size distribution.

Bubble and Slug Flow at Microgravity Conditions: State of Knowledge and Open Questions

NASA Technical Reports Server (NTRS)

Colin, C.; Fabre, J.; McQuillen, J.

1996-01-01

Based on the experiments carried out over the past decade at microgravity conditions, an overview of our current knowledge of bubbly and slug flows is presented. The transition from bubble to slug flow, the void fraction and the pressure drop are discussed from the data collected in the literature. The transition from bubble to slug flow may be predicted by introducing a critical void fraction that depends on the fluid properties and the pipe diameter; however, the role of coalescence which controls this transition is not clearly understood. The void fraction may be accurately calculated using a drift-flux model. It is shown from local measurements that the drift of the gas with respect to the mixture is due to non-uniform radial distribution of void fraction. The pressure drop happens to be controlled by the liquid flow for bubbly flow whereas for slug flow the experimental results show that pressure drops is larger than expected. From this study, the guidelines for future research in microgravity are given.

THE AGE OF THE LOCAL INTERSTELLAR BUBBLE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abt, Helmut A., E-mail: abt@noao.edu

2011-05-15

The Local Interstellar Bubble is an irregular region from 50 to 150 pc from the Sun in which the interstellar gas density is 10{sup -2}-10{sup -3} of that outside the bubble and the interstellar temperature is 10{sup 6} K. Evidently most of the gas was swept out by one or more supernovae. I explored the stellar contents and ages of the region from visual double stars, spectroscopic doubles, single stars, open clusters, emission regions, X-ray stars, planetary nebulae, and pulsars. The bubble has three sub-regions. The region toward the galactic center has stars as early as O9.5 V and withmore » ages of 2-4 M yr. It also has a pulsar (PSRJ1856-3754) with a spin-down age of 3.76 Myr. That pulsar is likely to be the remnant of the supernova that drove away most of the gas. The central lobe has stars as early as B7 V and therefore an age of about 160 Myr or less. The Pleiades lobe has stars as early as B3 and therefore an age of about 50 Myr. There are no obvious pulsars that resulted from the supernovae that cleared out those areas. As found previously by Welsh and Lallement, the bubble has five B stars along its perimeter that show high-temperature ions of O VI and C II along their lines of sight, confirming its high interstellar temperature.« less

Suppression of AGN-Driven G-Mode Turbulence by Magnetic Fields in a Magnetohydrodynamic Model of the Intracluster Medium

NASA Astrophysics Data System (ADS)

Bambic, Christopher J.; Morsony, Brian J.; Reynolds, Christopher S.

2017-08-01

We investigate the role of AGN feedback in turbulent heating of galaxy clusters. X-ray measurements of the Perseus Cluster intracluster medium (ICM) by the Hitomi Mission found a velocity dispersion measure of σ ˜ 164 km/s, indicating a large-scale turbulent energy of approximately 4% of the thermal energy. If this energy is transferred to small scales via a turbulent cascade and dissipated as heat, radiative cooling can be offset and the cluster can remain in the observed thermal equilibrium. Using 3D ideal MHD simulations and a plane-parallel model of the ICM, we analyze the production of turbulence by g-modes generated by the supersonic expansion and buoyant rise of AGN-driven bubbles. Previous work has shown that this process is inefficient, with less than 1% of the injected energy ending up in turbulence. Hydrodynamic instabilities shred the bubbles apart before they can excite sufficiently strong g-modes. We examine the role of a large-scale magnetic field which is able to drape around these rising bubbles, preserving them from instabilities. We show that a helical magnetic field geometry is able to better preserve bubbles, driving stronger g-modes; however, the production of turbulence is still inefficient. Magnetic tension acts to stabilize g-modes, preventing the nonlinear transition to turbulence. In addition, the magnetic tension force acts along the field lines to suppress the formation of small-scale vortices. These two effects halt the turbulent cascade. Our work shows that ideal MHD is an insufficient description for the cluster feedback process, and we discuss future work such as the inclusion of anisotropic viscosity as a means of simulating high β plasma kinetic effects. In addition, other mechanisms of heating the ICM plasma such as sound waves or cosmic rays may be responsible to account for observed feedback in galaxy clusters.

Bubble formation in water with addition of a hydrophobic solute.

PubMed

Okamoto, Ryuichi; Onuki, Akira

2015-07-01

We show that phase separation can occur in a one-component liquid outside its coexistence curve (CX) with addition of a small amount of a solute. The solute concentration at the transition decreases with increasing the difference of the solvation chemical potential between liquid and gas. As a typical bubble-forming solute, we consider O2 in ambient liquid water, which exhibits mild hydrophobicity and its critical temperature is lower than that of water. Such a solute can be expelled from the liquid to form gaseous domains while the surrounding liquid pressure is higher than the saturated vapor pressure p cx. This solute-induced bubble formation is a first-order transition in bulk and on a partially dried wall, while a gas film grows continuously on a completely dried wall. We set up a bubble free energy ΔG for bulk and surface bubbles with a small volume fraction ϕ. It becomes a function of the bubble radius R under the Laplace pressure balance. Then, for sufficiently large solute densities above a threshold, ΔG exhibits a local maximum at a critical radius and a minimum at an equilibrium radius. We also examine solute-induced nucleation taking place outside CX, where bubbles larger than the critical radius grow until attainment of equilibrium.

Low threshold lasing of bubble-containing glass microspheres by non-whispering gallery mode excitation over a wide wavelength range

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kumagai, Tsutaru, E-mail: kumagai.t.af@m.titech.ac.jp; Kishi, Tetsuo; Yano, Tetsuji

2015-03-21

Bubble-containing Nd{sup 3+}-doped tellurite glass microspheres were fabricated by localized laser heating technique to investigate their optical properties for use as microresonators. Fluorescence and excitation spectra measurements were performed by pumping with a tunable CW-Ti:Sapphire laser. The excitation spectra manifested several sharp peaks due to the conventional whispering gallery mode (WGM) when the pumping laser was irradiated to the edge part of the microsphere. However, when the excitation light was irradiated on the bubble position inside the microsphere, “non-WGM excitation” was induced, giving rise to numerous peaks at a broad wavelength range in the excitation spectra. Thus, efficient excitation wasmore » achieved over a wide wavelength range. Lasing threshold excited at the bubble position was much lower than that for the excitation at the edges of the microsphere. The lowest value of the laser threshold was 34 μW for a 4 μm sphere containing a 0.5 μm bubble. Efficiency of the excitation at the bubble position with broadband light was calculated to be 5 times higher than that for the edge of the microsphere. The bubble-containing microsphere enables efficient utilization of broadband light excitation from light-emitting diodes and solar light.« less

Analysis of transitional separation bubbles on infinite swept wings

NASA Technical Reports Server (NTRS)

Davis, R. L.; Carter, J. E.

1986-01-01

A previously developed two-dimensional local inviscid-viscous interaction technique for the analysis of airfoil transitional separation bubbles, ALESEP (Airfoil Leading Edge Separation), has been extended for the calculation of transitional separation bubbles over infinite swept wings. As part of this effort, Roberts' empirical correlation, which is interpreted as a separated flow empirical extension of Mack's stability theory for attached flows, has been incorporated into the ALESEP procedure for the prediction of the transition location within the separation bubble. In addition, the viscous procedure used in the ALESEP techniques has been modified to allow for wall suction. A series of two-dimensional calculations is presented as a verification of the prediction capability of the interaction techniques with the Roberts' transition model. Numerical tests have shown that this two-dimensional natural transition correlation may also be applied to transitional separation bubbles over infinite swept wings. Results of the interaction procedure are compared with Horton's detailed experimental data for separated flow over a swept plate which demonstrates the accuracy of the present technique. Wall suction has been applied to a similar interaction calculation to demonstrate its effect on the separation bubble. The principal conclusion of this paper is that the prediction of transitional separation bubbles over two-dimensional or infinite swept geometries is now possible using the present interacting boundary layer approach.

Morphological diagnostics of star formation in molecular clouds

NASA Astrophysics Data System (ADS)

Beaumont, Christopher Norris

Molecular clouds are the birth sites of all star formation in the present-day universe. They represent the initial conditions of star formation, and are the primary medium by which stars transfer energy and momentum back to parsec scales. Yet, the physical evolution of molecular clouds remains poorly understood. This is not due to a lack of observational data, nor is it due to an inability to simulate the conditions inside molecular clouds. Instead, the physics and structure of the interstellar medium are sufficiently complex that interpreting molecular cloud data is very difficult. This dissertation mitigates this problem, by developing more sophisticated ways to interpret morphological information in molecular cloud observations and simulations. In particular, I have focused on leveraging machine learning techniques to identify physically meaningful substructures in the interstellar medium, as well as techniques to inter-compare molecular cloud simulations to observations. These contributions make it easier to understand the interplay between molecular clouds and star formation. Specific contributions include: new insight about the sheet-like geometry of molecular clouds based on observations of stellar bubbles; a new algorithm to disambiguate overlapping yet morphologically distinct cloud structures; a new perspective on the relationship between molecular cloud column density distributions and the sizes of cloud substructures; a quantitative analysis of how projection effects affect measurements of cloud properties; and an automatically generated, statistically-calibrated catalog of bubbles identified from their infrared morphologies.

Method for electrically producing dispersions of a nonconductive fluid in a conductive medium

DOEpatents

DePaoli, D.W.; Tsouris, C.; Feng, J.Q.

1998-06-09

A method is described for use in electrically forming dispersions of a nonconducting fluid in a conductive medium that minimizes power consumption, gas generation, and sparking between the electrode of the nozzle and the conductive medium. The method utilizes a nozzle having a passageway, the wall of which serves as the nozzle electrode, for the transport of the nonconducting fluid into the conductive medium. A second passageway provides for the transport of a flowing low conductivity buffer fluid which results in a region of the low conductivity buffer fluid immediately adjacent the outlet from the first passageway to create the necessary protection from high current drain and sparking. An electrical potential difference applied between the nozzle electrode and an electrode in contact with the conductive medium causes formation of small droplets or bubbles of the nonconducting fluid within the conductive medium. A preferred embodiment has the first and second passageways arranged in a concentric configuration, with the outlet tip of the first passageway withdrawn into the second passageway. 4 figs.

Method for electrically producing dispersions of a nonconductive fluid in a conductive medium

DOEpatents

DePaoli, David W.; Tsouris, Constantinos; Feng, James Q.

1998-01-01

A method for use in electrically forming dispersions of a nonconducting fluid in a conductive medium that minimizes power consumption, gas generation, and sparking between the electrode of the nozzle and the conductive medium. The method utilizes a nozzle having a passageway, the wall of which serves as the nozzle electrode, for the transport of the nonconducting fluid into the conductive medium. A second passageway provides for the transport of a flowing low conductivity buffer fluid which results in a region of the low conductivity buffer fluid immediately adjacent the outlet from the first passageway to create the necessary protection from high current drain and sparking. An electrical potential difference applied between the nozzle electrode and an electrode in contact with the conductive medium causes formation of small droplets or bubbles of the nonconducting fluid within the conductive medium. A preferred embodiment has the first and second passageways arranged in a concentric configuration, with the outlet tip of the first passageway withdrawn into the second passageway.

Cultivation of Arthrospira (spirulina) platensis in desalinator wastewater and salinated synthetic medium: protein content and amino-acid profile

PubMed Central

Volkmann, Harriet; Imianovsky, Ulisses; Oliveira, Jorge L.B.; Sant’Anna, Ernani S.

2008-01-01

Arthrospira (Spirulina) platensis was cultivated in laboratory under controlled conditions (30°C, photoperiod of 12 hours light/dark provided by fluorescent lamps at a light intensity of 140 μmol photons.m-2.s-1 and constant bubbling air) in three different culture media: (1) Paoletti medium (control), (2) Paoletti supplemented with 1 g.L-1 NaCl (salinated water) and (3) Paoletti medium prepared with desalinator wastewater. The effects of these treatments on growth, protein content and amino acid profile were measured. Maximum cell concentrations observed in Paoletti medium, Paoletti supplemented with salinated water or with desalinator wastewater were 2.587, 3.545 and 4.954 g.L-1, respectively. Biomass in medium 3 presented the highest protein content (56.17%), while biomass in medium 2 presented 48.59% protein. All essential amino acids, except lysine and tryptophan, were found in concentrations higher than those requiried by FAO. PMID:24031187

The Structure of the Local Hot Bubble

NASA Technical Reports Server (NTRS)

Liu, W.; Chiao, M.; Collier, M. R.; Cravens, T.; Galeazzi, M.; Koutroumpa, D.; Kuntz, K. D.; Lallement, R.; Lepri, S. T.; McCammon, Dan;

Dynamic colloidal sorting on a magnetic bubble lattice

NASA Astrophysics Data System (ADS)

Tierno, Pietro; Soba, Alejandro; Johansen, Tom H.; Sagués, Francesc

2008-11-01

We use a uniaxial garnet film with a magnetic bubble lattice to sort paramagnetic colloidal particles with different diameters, i.e., 1.0 and 2.8μm. We apply an external magnetic field which precesses around an axis normal to the film with a frequency Ω =62.8s-1 and intensity 3120A/m

A Radio-Polarisation and Rotation Measure Study of the Gum Nebula and Its Environment

NASA Astrophysics Data System (ADS)

Purcell, C. R.; Gaensler, B. M.; Sun, X. H.; Carretti, E.; Bernardi, G.; Haverkorn, M.; Kesteven, M. J.; Poppi, S.; Schnitzeler, D. H. F. M.; Staveley-Smith, L.

2015-05-01

The Gum Nebula is 36°-wide shell-like emission nebula at a distance of only ˜450 pc. It has been hypothesized to be an old supernova remnant, fossil H ii region, wind-blown bubble, or combination of multiple objects. Here we investigate the magneto-ionic properties of the nebula using data from recent surveys: radio-continuum data from the NRAO VLA and S-band Parkes All Sky Surveys, and H α data from the Southern H-Alpha Sky Survey Atlas. We model the upper part of the nebula as a spherical shell of ionized gas expanding into the ambient medium. We perform a maximum-likelihood Markov chain Monte Carlo fit to the NVSS rotation measure data, using the H α data to constrain average electron density in the shell ne. Assuming a latitudinal background gradient in rotation measure, we find {{n}e}=1.3-0.4+0.4 c{{m}-3}, angular radius {{φ }outer}=22\\buildrel{\\circ}\\over{.} 7-0.1+0.1, shell thickness dr=18.5-1.4+1.5 pc, ambient magnetic field strength {{B}0}=3.9-2.2+4.9 μ G, and warm gas filling factor f=0.3-0.1+0.3. We constrain the local, small-scale (˜260 pc) pitch-angle of the ordered Galactic magnetic field to +7{}^\\circ ≲ \\wp ≲ +44{}^\\circ , which represents a significant deviation from the median field orientation on kiloparsec scales (˜-7.°2). The moderate compression factor X=6.0-2.5+5.1 at the edge of the H α shell implies that the “old supernova remnant” origin is unlikely. Our results support a model of the nebula as a H ii region around a wind-blown bubble. Analysis of depolarization in 2.3 GHz S-PASS data is consistent with this hypothesis and our best-fitting values agree well with previous studies of interstellar bubbles.

Sound field measurement in a double layer cavitation cluster by rugged miniature needle hydrophones.

PubMed

Koch, Christian

2016-03-01

During multi-bubble cavitation the bubbles tend to organize themselves into clusters and thus the understanding of properties and dynamics of clustering is essential for controlling technical applications of cavitation. Sound field measurements are a potential technique to provide valuable experimental information about the status of cavitation clouds. Using purpose-made, rugged, wide band, and small-sized needle hydrophones, sound field measurements in bubble clusters were performed and time-dependent sound pressure waveforms were acquired and analyzed in the frequency domain up to 20 MHz. The cavitation clusters were synchronously observed by an electron multiplying charge-coupled device (EMCCD) camera and the relation between the sound field measurements and cluster behaviour was investigated. Depending on the driving power, three ranges could be identified and characteristic properties were assigned. At low power settings no transient and no or very low stable cavitation activity can be observed. The medium range is characterized by strong pressure peaks and various bubble cluster forms. At high power a stable double layer was observed which grew with further increasing power and became quite dynamic. The sound field was irregular and the fundamental at driving frequency decreased. Between the bubble clouds completely different sound field properties were found in comparison to those in the cloud where the cavitation activity is high. In between the sound field pressure amplitude was quite small and no collapses were detected. Copyright © 2015. Published by Elsevier B.V.

Testing eternal inflation with the kinetic Sunyaev Zel'dovich effect

NASA Astrophysics Data System (ADS)

Zhang, Pengjie; Johnson, Matthew C.

2015-06-01

Perhaps the most controversial idea in modern cosmology is that our observable universe is contained within one bubble among many, all inhabiting the eternally inflating multiverse. One of the few way to test this idea is to look for evidence of the relic inhomogeneities left by the collisions between other bubbles and our own. Such relic inhomogeneities will induce a coherent bulk flow over Gpc scales. Therefore, bubble collisions leave unique imprints in the cosmic microwave background (CMB) through the kinetic Sunyaev Zel'dovich (kSZ) effect, temperature anisotropies induced by the scattering of photons from coherently moving free electrons in the diffuse intergalactic medium. The kSZ signature produced by bubble collisions has a unique directional dependence and is tightly correlated with the galaxy distribution; it can therefore be distinguished from other contributions to the CMB anisotropies. An important advantage of the kSZ signature is that it peaks on arcminute angular scales, where the limiting factors in making a detection are instrumental noise and foreground subtraction. This is in contrast to the collision signature in the primary CMB, which peaks on angular scales much larger than one degree, and whose detection is therefore limited by cosmic variance. In this paper, we examine the prospects for probing the inhomogeneities left by bubble collisions using the kSZ effect. We provide a forecast for detection using cross-correlations between CMB and galaxy surveys, finding that the detectability using the kSZ effect can be competitive with constraints from CMB temperature and polarization data.

A NEW ELECTRON-DENSITY MODEL FOR ESTIMATION OF PULSAR AND FRB DISTANCES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yao, J. M.; Wang, N.; Manchester, R. N.

2017-01-20

We present a new model for the distribution of free electrons in the Galaxy, the Magellanic Clouds, and the intergalactic medium (IGM) that can be used to estimate distances to real or simulated pulsars and fast radio bursts (FRBs) based on their dispersion measure (DM). The Galactic model has an extended thick disk representing the so-called warm interstellar medium, a thin disk representing the Galactic molecular ring, spiral arms based on a recent fit to Galactic H ii regions, a Galactic Center disk, and seven local features including the Gum Nebula, Galactic Loop I, and the Local Bubble. An offsetmore » of the Sun from the Galactic plane and a warp of the outer Galactic disk are included in the model. Parameters of the Galactic model are determined by fitting to 189 pulsars with independently determined distances and DMs. Simple models are used for the Magellanic Clouds and the IGM. Galactic model distances are within the uncertainty range for 86 of the 189 independently determined distances and within 20% of the nearest limit for a further 38 pulsars. We estimate that 95% of predicted Galactic pulsar distances will have a relative error of less than a factor of 0.9. The predictions of YMW16 are compared to those of the TC93 and NE2001 models showing that YMW16 performs significantly better on all measures. Timescales for pulse broadening due to interstellar scattering are estimated for (real or simulated) Galactic and Magellanic Cloud pulsars and FRBs.« less

Multiphase fluid-solid coupled analysis of shock-bubble-stone interaction in shockwave lithotripsy.

PubMed

Wang, Kevin G

2017-10-01

A novel multiphase fluid-solid-coupled computational framework is applied to investigate the interaction of a kidney stone immersed in liquid with a lithotripsy shock wave (LSW) and a gas bubble near the stone. The main objective is to elucidate the effects of a bubble in the shock path to the elastic and fracture behaviors of the stone. The computational framework couples a finite volume 2-phase computational fluid dynamics solver with a finite element computational solid dynamics solver. The surface of the stone is represented as a dynamic embedded boundary in the computational fluid dynamics solver. The evolution of the bubble surface is captured by solving the level set equation. The interface conditions at the surfaces of the stone and the bubble are enforced through the construction and solution of local fluid-solid and 2-fluid Riemann problems. This computational framework is first verified for 3 example problems including a 1D multimaterial Riemann problem, a 3D shock-stone interaction problem, and a 3D shock-bubble interaction problem. Next, a series of shock-bubble-stone-coupled simulations are presented. This study suggests that the dynamic response of a bubble to LSW varies dramatically depending on its initial size. Bubbles with an initial radius smaller than a threshold collapse within 1 μs after the passage of LSW, whereas larger bubbles do not. For a typical LSW generated by an electrohydraulic lithotripter (p max  = 35.0MPa, p min  =- 10.1MPa), this threshold is approximately 0.12mm. Moreover, this study suggests that a noncollapsing bubble imposes a negative effect on stone fracture as it shields part of the LSW from the stone. On the other hand, a collapsing bubble may promote fracture on the proximal surface of the stone, yet hinder fracture from stone interior. Copyright © 2016 John Wiley & Sons, Ltd.

Biomedical device prototype based on small scale hydrodynamic cavitation

NASA Astrophysics Data System (ADS)

Ghorbani, Morteza; Sozer, Canberk; Alcan, Gokhan; Unel, Mustafa; Ekici, Sinan; Uvet, Huseyin; Koşar, Ali

2018-03-01

This study presents a biomedical device prototype based on small scale hydrodynamic cavitation. The application of small scale hydrodynamic cavitation and its integration to a biomedical device prototype is offered as an important alternative to other techniques, such as ultrasound therapy, and thus constitutes a local, cheap, and energy-efficient solution, for urinary stone therapy and abnormal tissue ablation (e.g., benign prostate hyperplasia (BPH)). The destructive nature of bubbly, cavitating, flows was exploited, and the potential of the prototype was assessed and characterized. Bubbles generated in a small flow restrictive element (micro-orifice) based on hydrodynamic cavitation were utilized for this purpose. The small bubbly, cavitating, flow generator (micro-orifice) was fitted to a small flexible probe, which was actuated with a micromanipulator using fine control. This probe also houses an imaging device for visualization so that the emerging cavitating flow could be locally targeted to the desired spot. In this study, the feasibility of this alternative treatment method and its integration to a device prototype were successfully accomplished.

Local phase transitions in driven colloidal suspensions

NASA Astrophysics Data System (ADS)

Scacchi, A.; Brader, J. M.

2018-02-01

Using dynamical density functional theory and Brownian dynamics simulations, we investigate the influence of a driven tracer particle on the density distribution of a colloidal suspension at a thermodynamic state point close to the liquid side of the binodal. In bulk systems, we find that a localised region of the colloid-poor phase, a 'cavitation bubble', forms behind the moving tracer. The extent of the cavitation bubble is investigated as a function of both the size and velocity of the tracer. The addition of a confining boundary enables us to investigate the interaction between the local phase instability at the substrate and that at the particle surface. When both the substrate and tracer interact repulsively with the colloids we observe the formation of a colloid-poor bridge between the substrate and the tracer. When a shear flow is applied parallel to the substrate the bridge becomes distorted and, at sufficiently high shear-rates, disconnects from the substrate to form a cavitation bubble.

Modeling the Variable Heliopause Location

NASA Astrophysics Data System (ADS)

Hensley, Kerry

2018-03-01

In 2012, Voyager 1 zipped across the heliopause. Five and a half years later, Voyager 2 still hasnt followed its twin into interstellar space. Can models of the heliopause location help determine why?How Far to the Heliopause?Artists conception of the heliosphere with the important structures and boundaries labeled. [NASA/Goddard/Walt Feimer]As our solar system travels through the galaxy, the solar outflow pushes against the surrounding interstellar medium, forming a bubble called the heliosphere. The edge of this bubble, the heliopause, is the outermost boundary of our solar system, where the solar wind and the interstellar medium meet. Since the solar outflow is highly variable, the heliopause is constantly moving with the motion driven by changes inthe Sun.NASAs twin Voyager spacecraft were poisedto cross the heliopause after completingtheir tour of the outer planets in the 1980s. In 2012, Voyager 1 registered a sharp increase in the density of interstellar particles, indicating that the spacecraft had passed out of the heliosphere and into the interstellar medium. The slower-moving Voyager 2 was set to pierce the heliopause along a different trajectory, but so far no measurements have shown that the spacecraft has bid farewell to oursolar system.In a recent study, ateam of scientists led by Haruichi Washimi (Kyushu University, Japan and CSPAR, University of Alabama-Huntsville) argues that models of the heliosphere can help explain this behavior. Because the heliopause location is controlled by factors that vary on many spatial and temporal scales, Washimiand collaborators turn to three-dimensional, time-dependent magnetohydrodynamics simulations of the heliosphere. In particular, they investigate how the position of the heliopause along the trajectories of Voyager 1 and Voyager 2 changes over time.Modeled location of the heliopause along the paths of Voyagers 1 (blue) and 2 (orange). Click for a closer look. The red star indicates the location at which Voyager 1 crossed the heliopause. The current location of Voyager 2 is marked with a red circle. [Washimi et al. 2017]A Time-Varying BarrierThe authorsconsider the impact that solar flares, coronal mass ejections, and other disturbances in the solar outflow have on the heliopause distance. These solar disturbances intermingle as they travel outward to form what the authors call global merged interaction regions.Using their hydrodynamical simulations, Washimi and collaborators capture the complex behavior of the global merged interaction regions as they propagate through the termination shock and collide with the heliopause. Part of the shock is transmitted into the local interstellar medium, while part of it is reflected back toward and collides with the termination shock, which is pushed toward the Sun. This complex interplay of transmitted and reflected shocks combined with the nonuniformity of the local interstellar medium causes the heliopause location to vary dramatically in time as well as space.What Does this Mean for Voyager 2?Washimi and collaborators find that the location of the heliopause along the trajectories of Voyagers 1 and 2 has changed considerably over the past decade. In particular, they find that the heliopause has been pushed outward over the past few years due to an increase in the solar wind ram pressure. According to their simulations, Voyager 2 is currently traveling outward faster than the heliopause is advancing, which means that the spacecraft should soon cross the boundary perhaps even thisyear to become Earths second interstellar messenger.CitationHaruichi Washimi et al 2017 ApJL 846 L9. doi:10.3847/2041-8213/aa8556

Torsional stress in DNA limits collaboration among reverse gyrase molecules.

PubMed

Ogawa, Taisaku; Sutoh, Kazuo; Kikuchi, Akihiko; Kinosita, Kazuhiko

2016-04-01

Reverse gyrase is an enzyme that can overwind (introduce positive supercoils into) DNA using the energy obtained from ATP hydrolysis. The enzyme is found in hyperthermophiles, and the overwinding reaction generally requires a temperature above 70 °C. In a previous study using microscopy, we have shown that 30 consecutive mismatched base pairs (a bubble) in DNA serve as a well-defined substrate site for reverse gyrase, warranting the processive overwinding activity down to 50 °C. Here, we inquire how multiple reverse gyrase molecules may collaborate with each other in overwinding one DNA molecule. We introduced one, two, or four bubbles in a linear DNA that tethered a magnetic bead to a coverslip surface. At 40-71 °C in the presence of reverse gyrase, the bead rotated clockwise as viewed from above, to relax the DNA twisted by reverse gyrase. Dependence on the enzyme concentration indicated that each bubble binds reverse gyrase tightly (dissociation constant < 0.1 nm) and that bound enzyme continuously overwinds DNA for > 5 min. Rotation with two bubbles was significantly faster compared with one bubble, indicating that overwinding actions are basically additive, but four bubbles did not show further acceleration except at 40 °C where the activity was very low. The apparent saturation is due to the hydrodynamic friction against the rotating bead, as confirmed by increasing the medium viscosity. When torsional stress in the DNA, determined by the friction, approaches ~ 7 pN·nm (at 71 °C), the overwinding activity of reverse gyrase drops sharply. Multiple molecules of reverse gyrase collaborate additively within this limit. © 2016 The Authors. The FEBS Journal published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.

Bubble nucleation in simple and molecular liquids via the largest spherical cavity method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gonzalez, Miguel A., E-mail: m.gonzalez12@imperial.ac.uk; Department of Chemistry, Imperial College London, London SW7 2AZ; Abascal, José L. F.

2015-04-21

In this work, we propose a methodology to compute bubble nucleation free energy barriers using trajectories generated via molecular dynamics simulations. We follow the bubble nucleation process by means of a local order parameter, defined by the volume of the largest spherical cavity (LSC) formed in the nucleating trajectories. This order parameter simplifies considerably the monitoring of the nucleation events, as compared with the previous approaches which require ad hoc criteria to classify the atoms and molecules as liquid or vapor. The combination of the LSC and the mean first passage time technique can then be used to obtain themore » free energy curves. Upon computation of the cavity distribution function the nucleation rate and free-energy barrier can then be computed. We test our method against recent computations of bubble nucleation in simple liquids and water at negative pressures. We obtain free-energy barriers in good agreement with the previous works. The LSC method provides a versatile and computationally efficient route to estimate the volume of critical bubbles the nucleation rate and to compute bubble nucleation free-energies in both simple and molecular liquids.« less

Numerical simulation and experimental validation of the dynamics of multiple bubble merger during pool boiling under microgravity conditions.

PubMed

Abarajith, H S; Dhir, V K; Warrier, G; Son, G

2004-11-01

Numerical simulation and experimental validation of the growth and departure of multiple merging bubbles and associated heat transfer on a horizontal heated surface during pool boiling under variable gravity conditions have been performed. A finite difference scheme is used to solve the equations governing mass, momentum, and energy in the vapor liquid phases. The vapor-liquid interface is captured by a level set method that is modified to include the influence of phase change at the liquid-vapor interface. Water is used as test liquid. The effects of reduced gravity condition and orientation of the bubbles on the bubble diameter, interfacial structure, bubble merger time, and departure time, as well as local heat fluxes, are studied. In the experiments, multiple vapor bubbles are produced on artificial cavities in the 2-10 micrometer diameter range, microfabricated on the polished silicon wafer with given spacing. The wafer was heated electrically from the back with miniature strain gage type heating elements in order to control the nucleation superheat. The experiments conducted in normal Earth gravity and in the low gravity environment of KC-135 aircraft are used to validate the numerical simulations.

Controlled-Turbulence Bioreactors

NASA Technical Reports Server (NTRS)

Wolf, David A.; Schwartz, Ray; Trinh, Tinh

1989-01-01

Two versions of bioreactor vessel provide steady supplies of oxygen and nutrients with little turbulence. Suspends cells in environment needed for sustenance and growth, while inflicting less damage from agitation and bubbling than do propeller-stirred reactors. Gentle environments in new reactors well suited to delicate mammalian cells. One reactor kept human kidney cells alive for as long as 11 days. Cells grow on carrier beads suspended in liquid culture medium that fills cylindrical housing. Rotating vanes - inside vessel but outside filter - gently circulates nutrient medium. Vessel stationary; magnetic clutch drives filter cylinder and vanes. Another reactor creates even less turbulence. Oxygen-permeable tubing wrapped around rod extending along central axis. Small external pump feeds oxygen to tubing through rotary coupling, and oxygen diffuses into liquid medium.

Spiral vane bioreactor

NASA Technical Reports Server (NTRS)

Morrison, Dennis R. (Inventor)

1991-01-01

A spiral vane bioreactor of a perfusion type is described in which a vertical chamber, intended for use in a microgravity condition, has a central rotating filter assembly and has flexible membranes disposed to rotate annularly about the filter assembly. The flexible members have end portions disposed angularly with respect to one another. A fluid replenishment medium is input from a closed loop liquid system to a completely liquid filled chamber containing microcarrier beads, cells and a fluid medium. Output of spent medium is to the closed loop. In the closed loop, the output and input parameters are sensed by sensors. A manifold permits recharging of the nutrients and pH adjustment. Oxygen is supplied and carbon dioxide and bubbles are removed and the system is monitored and controlled by a microprocessor.

Manipulation of micro-objects using acoustically oscillating bubbles based on the gas permeability of PDMS.

PubMed

Liu, Bendong; Tian, Baohua; Yang, Xu; Li, Mohan; Yang, Jiahui; Li, Desheng; Oh, Kwang W

2018-05-01

This paper presents a novel manipulation method for micro-objects using acoustically oscillating bubbles with a controllable position based on the gas permeability of polydimethylsiloxane. The oscillating bubble trapped within the side channel attracts the neighboring micro-objects, and the position of the air-liquid interface is controlled by generating temporary pressure difference between the side channel and the air channel. To demonstrate the feasibility of the method in technological applications, polystyrene microparticles of 10  μ m in diameter were successfully captured, transported, and released. The influence of pressure difference on the movement speed of the air-liquid interface was demonstrated in our experiments, and the manipulation performance was also characterized by varying the frequency of the acoustic excitation and the pressure difference. Since the bubble generation and the air-liquid interface movement in our manipulation method do not need any electrochemical reaction and any high temperature, this on-chip manipulation method provides a controllable, efficient, and noninvasive tool for handling micro-objects such as particles, cells, and other entities. The whole manipulation process, including capturing, transporting, and releasing of particles, spent less than 1 min. It can be used to select the cells and particles in the microfluidic device or change the cell culture medium.

Infrared dust bubble CS51 and its interaction with the surrounding interstellar medium

NASA Astrophysics Data System (ADS)

Das, Swagat R.; Tej, Anandmayee; Vig, Sarita; Liu, Hong-Li; Liu, Tie; Ishwara Chandra, C. H.; Ghosh, Swarna K.

2017-12-01

A multiwavelength investigation of the southern infrared dust bubble CS51 is presented in this paper. We probe the associated ionized, cold dust, molecular and stellar components. Radio continuum emission mapped at 610 and 1300 MHz, using the Giant Metrewave Radio Telescope, India, reveals the presence of three compact emission components (A, B, and C) apart from large-scale diffuse emission within the bubble interior. Radio spectral index map shows the co-existence of thermal and non-thermal emission components. Modified blackbody fits to the thermal dust emission using Herschel Photodetector Array Camera and Spectrometer and Spectral and Photometric Imaging Receiver data is performed to generate dust temperature and column density maps. We identify five dust clumps associated with CS51 with masses and radius in the range 810-4600 M⊙ and 1.0-1.9 pc, respectively. We further construct the column density probability distribution functions of the surrounding cold dust which display the impact of ionization feedback from high-mass stars. The estimated dynamical and fragmentation time-scales indicate the possibility of collect and collapse mechanism in play at the bubble border. Molecular line emission from the Millimeter Astronomy Legacy Team 90 GHz survey is used to understand the nature of two clumps which show signatures of expansion of CS51.

Flow analysis from PIV in engraved champagne tasting glasses: flute versus coupe

NASA Astrophysics Data System (ADS)

Beaumont, Fabien; Liger-Belair, Gérard; Polidori, Guillaume

2015-08-01

Glass shape, and especially its open aperture, is suspected to play an important role as concerns the kinetics of CO2 and flavor release during champagne tasting. In recent years, much interest has been devoted to depict each and every parameter involved in the release of gaseous CO2 from glasses poured with champagne. One cannot understand the bubbling and aromatic exhalation events in champagne tasting, however, without studying the flow-mixing mechanisms inside the glass. Indeed, a key assumption is that a causal link may exist between flow structures created in the wine due to bubble motion and the process of CO2 release and flavor exhalation. In the present work, two quite emblematic types of champagne drinking vessels are studied. The particle image velocimetry technique has been used in order to reveal the velocity field of the liquid due to the ascending bubble-driven flow for both glasses poured with champagne. The contribution of glass shape on the flow patterns and CO2 release in both glasses are discussed by the use of experimental results. The results show that the continuous flow of ascending bubbles strongly modifies the mixing and convection conditions of the surrounding liquid medium whose behavior is strongly glass shape dependent.

Effects of viscosity on endothelial cell damage under acoustic droplet vaporization

NASA Astrophysics Data System (ADS)

Seda, Robinson; Singh, Rahul; Li, David; Pitre, John; Putnam, Andrew; Fowlkes, J. Brian; Bull, Joseph

2014-11-01

Acoustic droplet vaporization (ADV) is a process by which stabilized superheated microdroplets are able to undergo phase transition with the aid of focused ultrasound. Gas bubbles resulting from ADV can provide local occlusion of the blood vessels supplying diseased tissue, such as tumors. The ADV process can also induce bioeffects that increase vessel permeability, which is beneficial for localized drug delivery. Previous in vitro studies have demonstrated that vaporization at the endothelial layer will affect cell attachment and viability. Several hypotheses have been proposed to elucidate the mechanism of damage including the generation of normal and shear stresses during bubble expansion. A single 3.5 MHz ultrasound pulse consisting of 8 cycles (~2.3 μs) and a 6 MPa peak rarefactional pressure was used to induce ADV on endothelial cells in media of different viscosities. Carboxylmethyl cellulose was added to the cell media to increase the viscosity up to 300 cP to and aid in the reduction of stresses during bubble expansion. The likelihood of cell damage was decreased when compared to our control (~1 cP), but it was still present in some cases indicating that the mechanism of damage does not depend entirely on viscous stresses associated with bubble expansion. This work was supported by NIH Grant R01EB006476.

Microfluidic study of fast gas-liquid reactions.

PubMed

Li, Wei; Liu, Kun; Simms, Ryan; Greener, Jesse; Jagadeesan, Dinesh; Pinto, Sascha; Günther, Axel; Kumacheva, Eugenia

2012-02-15

We present a new concept for studies of the kinetics of fast gas-liquid reactions. The strategy relies on the microfluidic generation of highly monodisperse gas bubbles in the liquid reaction medium and subsequent analysis of time-dependent changes in bubble dimensions. Using reactions of CO(2) with secondary amines as an exemplary system, we demonstrate that the method enables rapid determination of reaction rate constant and conversion, and comparison of various binding agents. The proposed approach addresses two challenges in studies of gas-liquid reactions: a mass-transfer limitation and a poorly defined gas-liquid interface. The proposed strategy offers new possibilities in studies of the fundamental aspects of rapid multiphase reactions, and can be combined with throughput optimization of reaction conditions.

Turbulent water flow in a channel at Reτ = 400 laden with 0.25 mm diameter air-bubbles clustered near the wall

NASA Astrophysics Data System (ADS)

Lakehal, D.; Métrailler, D.; Reboux, S.

2017-06-01

This paper presents Direct Numerical Simulation (DNS) results of a turbulent water flow in a channel at Reτ = 400 laden with 0.25 mm diameter air bubbles clustered near the wall (maximum void fraction of α = 8% at y+ ˜ 20). The bubbles were fully resolved using the level set approach built within the CFD/CMFD code TransAT. The fluid properties (air and water) were kept real, including density, viscosity, and surface tension coefficient. The aim of this work is to understand the effects of the bubbles on near-wall turbulence, paving the way towards convective wall-boiling flow studies. The interactions between the gas bubbles and the water stream were studied through an in-depth analysis of the turbulence statistics. The near-wall flow is overall affected by the bubbles, which act like roughness elements during the early phase, prior to their departure from the wall. The average profiles are clearly altered by the bubbles dynamics near the wall, which somewhat contrasts with the findings from similar studies [J. Lu and G. Tryggvason, "Dynamics of nearly spherical bubbles in a turbulent channel upflow," J. Fluid Mech. 732, 166 (2013)], most probably because the bubbles were introduced uniformly in the flow and not concentrated at the wall. The shape of the bubbles measured as the apparent to initial diameter ratio is found to change by a factor of at least two, in particular at the later stages when the bubbles burst out from the boundary layer. The clustering of the bubbles seems to be primarily localized in the zone populated by high-speed streaks and independent of their size. More importantly, the bubbly flow seems to differ from the single-phase flow in terms of turbulent stress distribution and energy exchange, in which all the stress components seem to be increased in the region very close to the wall, by up to 40%. The decay in the energy spectra near the wall was found to be significantly slower for the bubbly flow than for a single-phase flow, which confirms that the bubbles increase the energy at smaller scales. The coherent structures in the boundary layer are broken by the bubbles, which disrupts the formation of long structures, reducing the streamwise integral length scale.

Design and fabrication of miniaturized PEM fuel cell combined microreactor with self-regulated hydrogen mechanism

NASA Astrophysics Data System (ADS)

Balakrishnan, A.; Frei, M.; Kerzenmacher, S.; Reinecke, H.; Mueller, C.

2015-12-01

In this work we present the design and fabrication of the miniaturized PEM fuel cell combined microreactor system with hydrogen regulation mechanism and testing of prototype microreactor. The system consists of two components (i) fuel cell component and (ii) microreactor component. The fuel cell component represents the miniaturized PEM fuel cell system (combination of screen printed fuel cell assembly and an on-board hydrogen storage medium). Hydrogen production based on catalytic hydrolysis of chemical hydride takes place in the microreactor component. The self-regulated hydrogen mechanism based on the gaseous hydrogen produced from the catalytic hydrolysis of sodium borohydride (NaBH4) gets accumulated as bubbles at the vicinity of the hydrophobic coated hydrogen exhaust holes. When the built up hydrogen bubbles pressure exceeds the burst pressure at the hydrogen exhaust holes the bubble collapses. This collapse causes a surge of fresh NaBH4 solution onto the catalyst surface leading to the removal of the reaction by-products formed at the active sites of the catalyst. The catalyst used in the system is platinum deposited on a base substrate. Nickel foam, carbon porous medium (CPM) and ceramic plate were selected as candidates for base substrate for developing a robust catalyst surface. For the first time the platinum layer fabricated by pulsed electrodeposition and dealloying (EPDD) technique is used for hydrolysis of NaBH4. The major advantages of such platinum catalyst layers are its high surface area and their mechanical stability. Prototype microreactor system with self-regulated hydrogen mechanism is demonstrated.

Flow regimes and mechanistic modeling of critical heat flux under subcooled flow boiling conditions

NASA Astrophysics Data System (ADS)

Le Corre, Jean-Marie

Thermal performance of heat flux controlled boiling heat exchangers are usually limited by the Critical Heat Flux (CHF) above which the heat transfer degrades quickly, possibly leading to heater overheating and destruction. In an effort to better understand the phenomena, a literature review of CHF experimental visualizations under subcooled flow boiling conditions was performed and systematically analyzed. Three major types of CHF flow regimes were identified (bubbly, vapor clot and slug flow regime) and a CHF flow regime map was developed, based on a dimensional analysis of the phenomena and available data. It was found that for similar geometric characteristics and pressure, a Weber number (We)/thermodynamic quality (x) map can be used to predict the CHF flow regime. Based on the experimental observations and the review of the available CHF mechanistic models under subcooled flow boiling conditions, hypothetical CHF mechanisms were selected for each CHF flow regime, all based on a concept of wall dry spot overheating, rewetting prevention and subsequent dry spot spreading. It is postulated that a high local wall superheat occurs locally in a dry area of the heated wall, due to a cyclical event inherent to the considered CHF two-phase flow regime, preventing rewetting (Leidenfrost effect). The selected modeling concept has the potential to span the CHF conditions from highly subcooled bubbly flow to early stage of annular flow. A numerical model using a two-dimensional transient thermal analysis of the heater undergoing nucleation was developed to mechanistically predict CHF in the case of a bubbly flow regime. In this type of CHF two-phase flow regime, the high local wall superheat occurs underneath a nucleating bubble at the time of bubble departure. The model simulates the spatial and temporal heater temperature variations during nucleation at the wall, accounting for the stochastic nature of the boiling phenomena. The model has also the potential to evaluate the post-DNB heater temperature up to the point of heater melting. Validation of the proposed model was performed using detailed measured wall boiling parameters near CHF, thereby bypassing most needed constitutive relations. It was found that under limiting nucleation conditions; a peak wall temperature at the time of bubble departure can be reached at CHF preventing wall cooling by quenching. The simulations show that the resulting dry patch can survive the surrounding quenching event, preventing further nucleation and leading to a fast heater temperature increase. For more practical applications, the model was applied at known CHF conditions in simple geometry coupled with one-dimensional and three-dimensional (CFD) codes. It was found that, in the case where CHF occurs under bubbly flow conditions, the local wall superheat underneath nucleating bubbles is predicted to reach the Leidenfrost temperature. However, a better knowledge of statistical variations in wall boiling parameters would be necessary to correctly capture the CHF trends with mass flux (or Weber number). In addition, consideration of relevant parameter influences on the Leidenfrost temperature and consideration of interfacial microphysics at the wall would allow improved simulation of the wall rewetting prevention and subsequent dry patch spreading.

Informative frame detection from wireless capsule video endoscopic images

NASA Astrophysics Data System (ADS)

Bashar, Md. Khayrul; Mori, Kensaku; Suenaga, Yasuhito; Kitasaka, Takayuki; Mekada, Yoshito

2008-03-01

Wireless capsule endoscopy (WCE) is a new clinical technology permitting the visualization of the small bowel, the most difficult segment of the digestive tract. The major drawback of this technology is the high amount of time for video diagnosis. In this study, we propose a method for informative frame detection by isolating useless frames that are substantially covered by turbid fluids or their contamination with other materials, e.g., faecal, semi-processed or unabsorbed foods etc. Such materials and fluids present a wide range of colors, from brown to yellow, and/or bubble-like texture patterns. The detection scheme, therefore, consists of two stages: highly contaminated non-bubbled (HCN) frame detection and significantly bubbled (SB) frame detection. Local color moments in the Ohta color space are used to characterize HCN frames, which are isolated by the Support Vector Machine (SVM) classifier in Stage-1. The rest of the frames go to the Stage-2, where Laguerre gauss Circular Harmonic Functions (LG-CHFs) extract the characteristics of the bubble-structures in a multi-resolution framework. An automatic segmentation method is designed to extract the bubbled regions based on local absolute energies of the CHF responses, derived from the grayscale version of the original color image. Final detection of the informative frames is obtained by using threshold operation on the extracted regions. An experiment with 20,558 frames from the three videos shows the excellent average detection accuracy (96.75%) by the proposed method, when compared with the Gabor based- (74.29%) and discrete wavelet based features (62.21%).

Radical production inside an acoustically driven microbubble.

PubMed

Stricker, Laura; Lohse, Detlef

2014-01-01

The chemical production of radicals inside acoustically driven bubbles is determined by the local temperature inside the bubbles and by their composition at collapse. By means of a previously validated ordinary differential equations (ODE) model [L. Stricker, A. Prosperetti, D. Lohse, Validation of an approximate model for the thermal behavior in acoustically driven bubbles, J. Acoust. Soc. Am. 130 (5) (2011) 3243-3251], based on boundary layer assumption for mass and heat transport, we study the influence of different parameters on the radical production. We perform different simulations by changing the driving frequency and pressure, the temperature of the surrounding liquid and the composition of the gas inside the bubbles. In agreement with the experimental conditions of new generation sonochemical reactors, where the bubbles undergo transient cavitation oscillations [D. F. Rivas, L. Stricker, A. Zijlstra, H. Gardeniers, D. Lohse, A. Prosperetti, Ultrasound artificially nucleated bubbles and their sonochemical radical production, Ultrason. Sonochem. 20 (1) (2013) 510-524], we mainly concentrate on the initial chemical transient and we suggest optimal working ranges for technological applications. The importance of the chemical composition at collapse is reflected in the model, including the role of entrapped water vapor. We in particular study the exothermal reactions taking place in H2 and O2 mixtures. At the exact stoichiometric mixture 2:1 the highest internal bubble temperatures are achieved. Copyright © 2013 Elsevier B.V. All rights reserved.

MR-based detection of individual histotripsy bubble clouds formed in tissues and phantoms.

PubMed

Allen, Steven P; Hernandez-Garcia, Luis; Cain, Charles A; Hall, Timothy L

2016-11-01

To demonstrate that MR sequences can detect individual histotripsy bubble clouds formed inside intact tissues. A line-scan and an EPI sequence were sensitized to histotripsy by inserting a bipolar gradient whose lobes bracketed the lifespan of a histotripsy bubble cloud. Using a 7 Tesla, small-bore scanner, these sequences monitored histotripsy clouds formed in an agar phantom and in vitro porcine liver and brain. The bipolar gradients were adjusted to apply phase with k-space frequencies of 10, 300 or 400 cm -1 . Acoustic pressure amplitude was also varied. Cavitation was simultaneously monitored using a passive cavitation detection system. Each image captured local signal loss specific to an individual bubble cloud. In the agar phantom, this signal loss appeared only when the transducer output exceeded the cavitation threshold pressure. In tissues, bubble clouds were immediately detected when the gradients created phase with k-space frequencies of 300 and 400 cm -1 . When the gradients created phase with a k-space frequency of 10 cm -1 , individual bubble clouds were not detectable until many acoustic pulses had been applied to the tissue. Cavitation-sensitive MR-sequences can detect single histotripsy bubble clouds formed in biologic tissue. Detection is influenced by the sensitizing gradients and treatment history. Magn Reson Med 76:1486-1493, 2016. © 2015 International Society for Magnetic Resonance in Medicine. © 2015 International Society for Magnetic Resonance in Medicine.

What can be Learned from X-ray Spectroscopy Concerning Hot Gas in Local Bubble and Charge Exchange Processes?

NASA Technical Reports Server (NTRS)

Snowden, Steve

2007-01-01

What can be learned from x-ray spectroscopy in observing hot gas in local bubble and charge exchange processes depends on spectral resolution, instrumental grasp, instrumental energy band, signal-to-nose, field of view, angular resolution and observatory location. Early attempts at x-ray spectroscopy include ROSAT; more recently, astronomers have used diffuse x-ray spectrometers, XMM Newton, sounding rocket calorimeters, and Suzaku. Future observations are expected with calorimeters on the Spectrum Roentgen Gamma mission, and the Solar Wind Charge Exchange (SWCX). The Geospheric SWCX may provide remote sensing of the solar wind and magnetosheath and remote observations of solar CMEs moving outward from the sun.

Observation of interaction of shock wave with gas bubble by image converter camera

NASA Astrophysics Data System (ADS)

Yoshii, M.; Tada, M.; Tsuji, T.; Isuzugawa, Kohji

1995-05-01

When a spark discharge occurs at the first focal point of a semiellipsoid or a reflector located in water, a spherical shock wave is produced. A part of the wave spreads without reflecting on the reflector and is called direct wave in this paper. Another part reflects on the semiellipsoid and converges near the second focal point, that is named the focusing wave, and locally produces a high pressure. This phenomenon is applied to disintegrators of kidney stone. But it is concerned that cavitation bubbles induced in the body by the expansion wave following the focusing wave will injure human tissue around kidney stone. In this paper, in order to examine what happens when shock waves strike bubbles on human tissue, the aspect that an air bubble is truck by the spherical shock wave or its behavior is visualized by the schlieren system and its photographs are taken using an image converter camera. Besides,the variation of the pressure amplitude caused by the shock wave and the flow of water around the bubble is measured with a pressure probe.

Optofluidic microvalve-on-a-chip with a surface plasmon-enhanced fiber optic microheater

PubMed Central

Zhang, Zhijian; Kusimo, Abisola; Yu, Miao

2014-01-01

We present an optofluidic microvalve utilizing an embedded, surface plasmon-enhanced fiber optic microheater. The fiber optic microheater is formed by depositing a titanium thin film on the roughened end-face of a silica optical fiber that serves as a waveguide to deliver laser light to the titanium film. The nanoscale roughness at the titanium-silica interface enables strong light absorption enhancement in the titanium film through excitation of localized surface plasmons as well as facilitates bubble nucleation. Our experimental results show that due to the unique design of the fiber optic heater, the threshold laser power required to generate a bubble is greatly reduced and the bubble growth rate is significantly increased. By using the microvalve, stable vapor bubble generation in the microchannel is demonstrated, which does not require complex optical focusing and alignment. The generated vapor bubble is shown to successfully block a liquid flow channel with a size of 125 μm × 125 μm and a flow rate of ∼10 μl/min at ∼120 mW laser power. PMID:25538813

Light Scattering by Ice Crystals Containing Air Bubbles

NASA Astrophysics Data System (ADS)

Zhang, J.; Panetta, R. L.; Yang, P.; Bi, L.

2014-12-01

The radiative effects of ice clouds are often difficult to estimate accurately, but are very important for interpretation of observations and for climate modeling. Our understanding of these effects is primarily based on scattering calculations, but due to the variability in ice habit it is computationally difficult to determine the required scattering and absorption properties, and the difficulties are only compounded by the need to include consideration of air and carbon inclusions of the sort frequently observed in collected samples. Much of the previous work on effects of inclusions in ice particles on scattering properties has been conducted with variants of geometric optics methods. We report on simulations of scattering by ice crystals with enclosed air bubbles using the pseudo-spectral time domain method (PSTD) and improved geometric optics method (IGOM). A Bouncing Ball Model (BBM) is proposed as a parametrization of air bubbles, and the results are compared with Monte Carlo radiative transfer calculations. Consistent with earlier studies, we find that air inclusions lead to a smoothing of variations in the phase function, weakening of halos, and a reduction of backscattering. We extend these studies by examining the effects of the particular arrangement of a fixed number of bubbles, as well as the effects of splitting a given number of bubbles into a greater number of smaller bubbles with the same total volume fraction. The result shows that the phase function will not change much for stochastic distributed air bubbles. It also shows that local maxima of phase functions are smoothed out for backward directions, when we break bubbles into small ones, single big bubble scatter favors more forward scattering than multi small internal scatters.

Controlled single bubble cavitation collapse results in jet-induced injury in brain tissue.

PubMed

Canchi, Saranya; Kelly, Karen; Hong, Yu; King, Michael A; Subhash, Ghatu; Sarntinoranont, Malisa

2017-10-01

Multiscale damage due to cavitation is considered as a potential mechanism of traumatic brain injury (TBI) associated with explosion. In this study, we employed a TBI relevant hippocampal ex vivo slice model to induce bubble cavitation. Placement of single reproducible seed bubbles allowed control of size, number, and tissue location to visualize and measure deformation parameters. Maximum strain value was measured at 45 µs after bubble collapse, presented with a distinct contour and coincided temporally and spatially with the liquid jet. Composite injury maps combined this maximum strain value with maximum measured bubble size and location along with histological injury patterns. This facilitated the correlation of bubble location and subsequent jet direction to the corresponding regions of high strain which overlapped with regions of observed injury. A dynamic threshold strain range for tearing of cerebral cortex was estimated to be between 0.5 and 0.6. For a seed bubble placed underneath the hippocampus, cavitation induced damage was observed in hippocampus (local), proximal cerebral cortex (marginal) and the midbrain/forebrain (remote) upon histological evaluation. Within this test model, zone of cavitation injury was greater than the maximum radius of the bubble. Separation of apposed structures, tissue tearing, and disruption of cellular layers defined early injury patterns that were not detected in the blast-exposed half of the brain slice. Ultrastructural pathology of the neurons exposed to cavitation was characterized by disintegration of plasma membrane along with loss of cellular content. The developed test system provided a controlled experimental platform to study cavitation induced high strain deformations on brain tissue slice. The goal of the future studies will be to lower underpressure magnitude and cavitation bubble size for more sensitive evaluation of injury. Copyright © 2017 Elsevier Ltd. All rights reserved.

ISM abundances and history: a 3D, solar neighborhood view

NASA Astrophysics Data System (ADS)

Lallement, R.; Vergely, J.-L.; Puspitarini, L.

For observational reasons, the solar neighborhood is particularly suitable for the study of the multi-phase interstellar (IS) medium and the search for traces of its temporal evolution. On the other hand, by a number of aspects it seems to be a peculiar region. We use recent 3D maps of the IS dust based on color excess data as well as former maps of the gas to illustrate how such maps can be used to shed additional light on the specificity of the local medium, its history and abundance pattern. 3D maps reveal a gigantic cavity located in the third quadrant and connected to the Local Bubble, the latter itself running into an elongated cavity toward l≃ 70°. Most nearby cloud complexes of the so-called Gould belt but also more distant clouds seem to border a large fraction of this entire structure. The IS medium with the large cavity appears ionized and dust-poor, as deduced from ionized calcium and neutral sodium to dust ratios. The geometry favors the proposed scenario of Gould belt-Local Arm formation through the braking of a supercloud by interaction with a spiral density wave \\citep{olano01}. The highly variable D/H ratio in the nearby IS gas may also be spatially related to the global structure. We speculate about potential consequences of the supercloud encounter and dust-gas decoupling during its braking, in particular the formation of strong inhomogeneities in both the dust to gas abundance ratio and the dust characteristics: (i) during the ≃ 500 Myrs prior to the collision, dust within the supercloud may have been gradually, strongly enriched in D due to an absence of strong stellar formation and preferential adsorption of D \\citep{jura82,draine03} ; (ii) during its interaction with the Plane and the braking dust-rich and dust-poor regions may have formed due to differential gas drag, the dust being more concentrated in the dense areas; strong radiation pressure from OB associations at the boundary of the left-behind giant cavity may have also helped in emptying the cavity from its dust at the profit of the central parts of the supercloud ; (iii) present D/H variations could be due to the combination of those dust inhomogeneities and posterior, localized deuterium release by grains in recent star forming regions. In this case, the true local D/H ratio has an intermediate value within the observed range.

Imaging of targeted lipid microbubbles to detect cancer cells using third harmonic generation microscopy

PubMed Central

Harpel, Kaitlin; Baker, Robert Dawson; Amirsolaimani, Babak; Mehravar, Soroush; Vagner, Josef; Matsunaga, Terry O.; Banerjee, Bhaskar; Kieu, Khanh

2016-01-01

The use of receptor-targeted lipid microbubbles imaged by ultrasound is an innovative method of detecting and localizing disease. However, since ultrasound requires a medium between the transducer and the object being imaged, it is impractical to apply to an exposed surface in a surgical setting where sterile fields need be maintained and ultrasound gel may cause the bubbles to collapse. Multiphoton microscopy (MPM) is an emerging tool for accurate, label-free imaging of tissues and cells with high resolution and contrast. We have recently determined a novel application of MPM to be used for detecting targeted microbubble adherence to the upregulated plectin-receptor on pancreatic tumor cells. Specifically, the third-harmonic generation response can be used to detect bound microbubbles to various cell types presenting MPM as an alternative and useful imaging method. This is an interesting technique that can potentially be translated as a diagnostic tool for the early detection of cancer and inflammatory disorders. PMID:27446711

Stability Analysis of an Encapsulated Microbubble against Gas Diffusion

PubMed Central

Katiyar, Amit; Sarkar, Kausik

2009-01-01

Linear stability analysis is performed for a mathematical model of diffusion of gases from an encapsulated microbubble. It is an Epstein-Plesset model modified to account for encapsulation elasticity and finite gas permeability. Although, bubbles, containing gases other than air is considered, the final stable bubble, if any, contains only air, and stability is achieved only when the surrounding medium is saturated or oversaturated with air. In absence of encapsulation elasticity, only a neutral stability is achieved for zero surface tension, the other solution being unstable. For an elastic encapsulation, different equilibrium solutions are obtained depending on the saturation level and whether the surface tension is smaller or higher than the elasticity. For an elastic encapsulation, elasticity can stabilize the bubble. However, imposing a non-negativity condition on the effective surface tension (consisting of reference surface tension and the elastic stress) leads to an equilibrium radius which is only neutrally stable. If the encapsulation can support net compressive stress, it achieves actual stability. The linear stability results are consistent with our recent numerical findings. Physical mechanisms for the stability or instability of various equilibriums are provided. PMID:20005522

Portable rotating discharge plasma device

NASA Astrophysics Data System (ADS)

Dwyer, B. L.; Brooks, N. H.; Lee, R. L.

2011-10-01

We constructed two devices for the purpose of educational demonstration: a rotating tube containing media of two densities to demonstrate axial confinement and a similar device that uses pressure variation to convert a long plasma glow discharge into a long straight arc. In the first device, the buoyant force is countered by the centripetal force, which confines less dense materials to the center of the column. Similarly, a plasma arc heats the gas through which it passes, creating a hot gaseous bubble that is less dense than the surrounding medium. Rotating its containment envelope stabilizes this gas bubble in an analogous manner to an air bubble in a rotating tube of water. In addition to stabilization, the rotating discharge also exhibits a decrease in buoyancy-driven convection currents. This limits the power loss to the walls, which decreases the field strength requirement for maintaining the arc. These devices demonstrate principles of electrodynamics, plasma physics, and fluid mechanics. They are portable and safe for classroom use. Work supported by US DOE under DE-FC02-04ER54698 and the National Undergraduate Fellowship in Fusion Science and Engineering.

Investigation of transition from thermal- to solutal-Marangoni flow in dilute alcohol/water mixtures using nano-plasmonic heaters

NASA Astrophysics Data System (ADS)

Namura, Kyoko; Nakajima, Kaoru; Suzuki, Motofumi

2018-02-01

We experimentally investigated Marangoni flows around a microbubble in diluted 1-butanol/water, 2-propanol/water, and ethanol/water mixtures using the thermoplasmonic effect of gold nanoisland film. A laser spot on the gold nanoisland film acted as a highly localized heat source that was utilized to generate stable air microbubbles with diameters of 32-48 μm in the fluid and to induce a steep temperature gradient on the bubble surface. The locally heated bubble has a flow along the bubble surface, with the flow direction showing a clear transition depending on the alcohol concentrations. The fluid is driven from the hot to cold regions when the alcohol concentration is lower than the transition concentration, whereas it is driven from the cold to hot regions when the concentration is higher than the transition concentration. In addition, the transition concentration increases as the carbon number of the alcohol decreases. The observed flow direction transition is explained by the balance of the thermal- and solutal-Marangoni forces that are cancelled out for the transition concentration. The selective evaporation of the alcohol at the locally heated surface allows us to generate stable and rapid thermoplasmonic solutal-Marangoni flows in the alcohol/water mixtures.

Testing eternal inflation with the kinetic Sunyaev Zel'dovich effect

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Pengjie; Johnson, Matthew C., E-mail: zhangpj@sjtu.edu.cn, E-mail: mjohnson@perimeterinstitute.ca

2015-06-01

Perhaps the most controversial idea in modern cosmology is that our observable universe is contained within one bubble among many, all inhabiting the eternally inflating multiverse. One of the few way to test this idea is to look for evidence of the relic inhomogeneities left by the collisions between other bubbles and our own. Such relic inhomogeneities will induce a coherent bulk flow over Gpc scales. Therefore, bubble collisions leave unique imprints in the cosmic microwave background (CMB) through the kinetic Sunyaev Zel'dovich (kSZ) effect, temperature anisotropies induced by the scattering of photons from coherently moving free electrons in themore » diffuse intergalactic medium. The kSZ signature produced by bubble collisions has a unique directional dependence and is tightly correlated with the galaxy distribution; it can therefore be distinguished from other contributions to the CMB anisotropies. An important advantage of the kSZ signature is that it peaks on arcminute angular scales, where the limiting factors in making a detection are instrumental noise and foreground subtraction. This is in contrast to the collision signature in the primary CMB, which peaks on angular scales much larger than one degree, and whose detection is therefore limited by cosmic variance. In this paper, we examine the prospects for probing the inhomogeneities left by bubble collisions using the kSZ effect. We provide a forecast for detection using cross-correlations between CMB and galaxy surveys, finding that the detectability using the kSZ effect can be competitive with constraints from CMB temperature and polarization data.« less

The nature and energetics of AGN-driven perturbations in the hot gas in the Perseus Cluster

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhuravleva, I.; Churazov, E.; Arevalo, P.

In this paper, cores of relaxed galaxy clusters are often disturbed by AGN. Their Chandra observations revealed a wealth of structures induced by shocks, subsonic gas motions, bubbles of relativistic plasma, etc. In this paper, we determine the nature and energy content of gas fluctuations in the Perseus core by probing statistical properties of emissivity fluctuations imprinted in the soft- and hard-band X-ray images. About 80 per cent of the total variance of perturbations on ~8–70 kpc scales in the core have an isobaric nature, i.e. are consistent with subsonic displacements of the gas in pressure equilibrium with the ambientmore » medium. The observed variance translates to the ratio of energy in perturbations to thermal energy of ~13 per cent. In the region dominated by weak ‘ripples’, about half of the total variance is associated with isobaric perturbations on scales of a few tens of kpc. If these isobaric perturbations are induced by buoyantly rising bubbles, then these results suggest that most of the AGN-injected energy should first go into bubbles rather than into shocks. Using simulations of a shock propagating through the Perseus atmosphere, we found that models reproducing the observed features of a central shock have more than 50 per cent of the AGN-injected energy associated with the bubble enthalpy and only about 20 per cent is carried away with the shock. Such energy partition is consistent with the AGN-feedback model, mediated by bubbles of relativistic plasma, and supports the importance of turbulence in the cooling–heating balance.« less

The nature and energetics of AGN-driven perturbations in the hot gas in the Perseus Cluster

DOE PAGES

Zhuravleva, I.; Churazov, E.; Arevalo, P.; ...

2016-03-07

In this paper, cores of relaxed galaxy clusters are often disturbed by AGN. Their Chandra observations revealed a wealth of structures induced by shocks, subsonic gas motions, bubbles of relativistic plasma, etc. In this paper, we determine the nature and energy content of gas fluctuations in the Perseus core by probing statistical properties of emissivity fluctuations imprinted in the soft- and hard-band X-ray images. About 80 per cent of the total variance of perturbations on ~8–70 kpc scales in the core have an isobaric nature, i.e. are consistent with subsonic displacements of the gas in pressure equilibrium with the ambientmore » medium. The observed variance translates to the ratio of energy in perturbations to thermal energy of ~13 per cent. In the region dominated by weak ‘ripples’, about half of the total variance is associated with isobaric perturbations on scales of a few tens of kpc. If these isobaric perturbations are induced by buoyantly rising bubbles, then these results suggest that most of the AGN-injected energy should first go into bubbles rather than into shocks. Using simulations of a shock propagating through the Perseus atmosphere, we found that models reproducing the observed features of a central shock have more than 50 per cent of the AGN-injected energy associated with the bubble enthalpy and only about 20 per cent is carried away with the shock. Such energy partition is consistent with the AGN-feedback model, mediated by bubbles of relativistic plasma, and supports the importance of turbulence in the cooling–heating balance.« less

SCINTILLATION ARCS IN LOW-FREQUENCY OBSERVATIONS OF THE TIMING-ARRAY MILLISECOND PULSAR PSR J0437–4715

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhat, N. D. R.; Ord, S. M.; Tremblay, S. E.

2016-02-10

Low-frequency observations of pulsars provide a powerful means for probing the microstructure in the turbulent interstellar medium (ISM). Here we report on high-resolution dynamic spectral analysis of our observations of the timing-array millisecond pulsar PSR J0437–4715 with the Murchison Widefield Array (MWA), enabled by our recently commissioned tied-array beam processing pipeline for voltage data recorded from the high time resolution mode of the MWA. A secondary spectral analysis reveals faint parabolic arcs akin to those seen in high-frequency observations of pulsars with the Green Bank and Arecibo telescopes. Data from Parkes observations at a higher frequency of 732 MHz revealmore » a similar parabolic feature with a curvature that scales approximately as the square of the observing wavelength (λ{sup 2}) to the MWA's frequency of 192 MHz. Our analysis suggests that scattering toward PSR J0437–4715 predominantly arises from a compact region about 115 pc from the Earth, which matches well with the expected location of the edge of the Local Bubble that envelopes the local Solar neighborhood. As well as demonstrating new and improved pulsar science capabilities of the MWA, our analysis underscores the potential of low-frequency pulsar observations for gaining valuable insights into the local ISM and for characterizing the ISM toward timing-array pulsars.« less

New impact sensitivity test of liquid explosives

NASA Astrophysics Data System (ADS)

Tiutiaev, Andrei; Trebunskih, Valeri

The sensitivity of liquid explosive in the presence of gas bubbles increases many times as compared with the liquid without gas bubbles. Local hot spot in this case formed as a result of compression and heating of the gas inside the bubbles. If we consider that in the liquid as a result of convection, wave motion, shock, etc. gas bubbles are easily generated, the need to develop a method for determining sensitivity of liquid explosives to impact and a detailed study of the ignition explosives with bubbles is obvious. On a mathematical model of a single steam bubbles in the fluid theoretically considered the process of initiating explosive liquid systems to impact. For the experimental investigation, the well-known K-44 -II with the metal cap were used. Instead of the metal cap in the standard method in this paper there was polyurethane foam cylindrical container with LHE, which is easily deforms by impact. A large number of tests with different liquid explosives were made. It was found that the test LHE to impact with polyurethane foam to a large extent reflect the real mechanical sensitivity due to the small loss of impact energy on the deformation of the metal cap, as well as the best differentiation LHE sensitivity due to the higher resolution method . Results obtained in the samara state technical university.

Effect of Shock-Induced Cavitation Bubble Collapse on the damage in the Simulated Perineuronal Net of the Brain.

PubMed

Wu, Yuan-Ting; Adnan, Ashfaq

2017-07-13

The purpose of this study is to conduct modeling and simulation to understand the effect of shock-induced mechanical loading, in the form of cavitation bubble collapse, on damage to the brain's perineuronal nets (PNNs). It is known that high-energy implosion due to cavitation collapse is responsible for corrosion or surface damage in many mechanical devices. In this case, cavitation refers to the bubble created by pressure drop. The presence of a similar damage mechanism in biophysical systems has long being suspected but not well-explored. In this paper, we use reactive molecular dynamics (MD) to simulate the scenario of a shock wave induced cavitation collapse within the perineuronal net (PNN), which is the near-neuron domain of a brain's extracellular matrix (ECM). Our model is focused on the damage in hyaluronan (HA), which is the main structural component of PNN. We have investigated the roles of cavitation bubble location, shockwave intensity and the size of a cavitation bubble on the structural evolution of PNN. Simulation results show that the localized supersonic water hammer created by an asymmetrical bubble collapse may break the hyaluronan. As such, the current study advances current knowledge and understanding of the connection between PNN damage and neurodegenerative disorders.

Cavitation in ultrasound and shockwave therapy

NASA Astrophysics Data System (ADS)

Colonius, Tim

2014-11-01

Acoustic waves, especially high-intensity ultrasound and shock waves, are used for medical imaging and intra- and extra-corporeal manipulation of cells, tissue, and urinary calculi. Waves are currently used to treat kidney stone disease, plantar fasciitis, and bone nonunion, and they are being investigated as a technique to ablate cancer tumors and mediate drug delivery. In many applications, acoustic waves induce the expansion and collapse of preexisting or newly cavitating bubbles whose presence can either mediate the generation of localized stresses or lead to collateral damage, depending on how effectively they can be controlled. We describe efforts aimed at simulating the collapse of bubbles, both individually and in clusters, with the aim to characterize the induced mechanical stresses and strains. To simulate collapse of one or a few bubbles, compressible Euler and Navier-Stokes simulations of multi-component materials are performed with WENO-based shock and interface capturing schemes. Repetitive insonification generates numerous bubbles that are difficult to resolve numerically. Such clouds are also important in traditional engineering applications such as caveating hydrofoils. Models that incorporate the dynamics of an unresolved dispersed phase consisting of the bubble cloud are also developed. The results of several model problems including bubble collapse near rigid surfaces, bubble collapse near compliant surfaces and in small capillaries are analyzed. The results are processed to determine the potential for micron-sized preexisting gas bubbles to damage capillaries. The translation of the fundamental fluid dynamics into improvements in the design and clinical application of shockwave lithotripters will be discussed. NIH Grant PO1-DK043881.

Molecular dynamics simulations of bubble nucleation in dark matter detectors.

PubMed

Denzel, Philipp; Diemand, Jürg; Angélil, Raymond

2016-01-01

Bubble chambers and droplet detectors used in dosimetry and dark matter particle search experiments use a superheated metastable liquid in which nuclear recoils trigger bubble nucleation. This process is described by the classical heat spike model of F. Seitz [Phys. Fluids (1958-1988) 1, 2 (1958)PFLDAS0031-917110.1063/1.1724333], which uses classical nucleation theory to estimate the amount and the localization of the deposited energy required for bubble formation. Here we report on direct molecular dynamics simulations of heat-spike-induced bubble formation. They allow us to test the nanoscale process described in the classical heat spike model. 40 simulations were performed, each containing about 20 million atoms, which interact by a truncated force-shifted Lennard-Jones potential. We find that the energy per length unit needed for bubble nucleation agrees quite well with theoretical predictions, but the allowed spike length and the required total energy are about twice as large as predicted. This could be explained by the rapid energy diffusion measured in the simulation: contrary to the assumption in the classical model, we observe significantly faster heat diffusion than the bubble formation time scale. Finally we examine α-particle tracks, which are much longer than those of neutrons and potential dark matter particles. Empirically, α events were recently found to result in louder acoustic signals than neutron events. This distinction is crucial for the background rejection in dark matter searches. We show that a large number of individual bubbles can form along an α track, which explains the observed larger acoustic amplitudes.

Distinguishing models of reionization using future radio observations of 21-cm 1-point statistics

NASA Astrophysics Data System (ADS)

Watkinson, C. A.; Pritchard, J. R.

2014-10-01

We explore the impact of reionization topology on 21-cm statistics. Four reionization models are presented which emulate large ionized bubbles around overdense regions (21CMFAST/global-inside-out), small ionized bubbles in overdense regions (local-inside-out), large ionized bubbles around underdense regions (global-outside-in) and small ionized bubbles around underdense regions (local-outside-in). We show that first generation instruments might struggle to distinguish global models using the shape of the power spectrum alone. All instruments considered are capable of breaking this degeneracy with the variance, which is higher in outside-in models. Global models can also be distinguished at small scales from a boost in the power spectrum from a positive correlation between the density and neutral-fraction fields in outside-in models. Negative skewness is found to be unique to inside-out models and we find that pre-Square Kilometre Array (SKA) instruments could detect this feature in maps smoothed to reduce noise errors. The early, mid- and late phases of reionization imprint signatures in the brightness-temperature moments, we examine their model dependence and find pre-SKA instruments capable of exploiting these timing constraints in smoothed maps. The dimensional skewness is introduced and is shown to have stronger signatures of the early and mid-phase timing if the inside-out scenario is correct.

Single-bubble boiling under Earth's and low gravity

NASA Astrophysics Data System (ADS)

Khusid, Boris; Elele, Ezinwa; Lei, Qian; Tang, John; Shen, Yueyang

2017-11-01

Miniaturization of electronic systems in terrestrial and space applications is challenged by a dramatic increase in the power dissipation per unit volume with the occurrence of localized hot spots where the heat flux is much higher than the average. Cooling by forced gas or liquid flow appears insufficient to remove high local heat fluxes. Boiling that involves evaporation of liquid in a hot spot and condensation of vapor in a cold region can remove a significantly larger amount of heat through the latent heat of vaporization than force-flow cooling can carry out. Traditional methods for enhancing boiling heat transfer in terrestrial and space applications focus on removal of bubbles from the heating surface. In contrast, we unexpectedly observed a new boiling regime of water under Earth's gravity and low gravity in which a bubble was pinned on a small heater up to 270°C and delivered a heat flux up to 1.2 MW/m2 that was as high as the critical heat flux in the classical boiling regime on Earth .Low gravity measurements conducted in parabolic flights in NASA Boeing 727. The heat flux in flight and Earth's experiments was found to rise linearly with increasing the heater temperature. We will discuss physical mechanisms underlying heat transfer in single-bubble boiling. The work supported by NASA Grants NNX12AM26G and NNX09AK06G.

Interpretations of phenocryst embayments

NASA Astrophysics Data System (ADS)

Rust, Alison; Cashman, Katharine

2017-04-01

Phenocryst embayments in volcanic samples tend to be filled with glass, regardless of the crystallinity and vesicularly of the groundmass surrounding the phenocryst. Embayments are important in volcanology and magma petrology because: 1) they often provide the only areas of matrix glass sufficient for compositional analysis in microlite-rich samples; 2) volatile gradients in embayments are used to constrain rates of magma ascent; 3) with further crystal growth, embayments may develop into melt inclusions, an essential source of data on melt composition evolution. Robust interpretations of data from embayments requires an understanding of why they form and why vesiculation and crystallisation are locally suppressed in these melt channels during ascent. We review instabilities in crystal growth and resorption, considering latent heat, local accumulation of elements, and interaction of the crystal growth front with pre-existing bubbles and other crystals. A survey of textures in volcanic samples from several volcanoes suggests that embayment formation by growth is more common than by resorption. Crystal nucleation suppression in the embayment of a growing phenocryst can be explained by buildup of excluded elements and continued growth (rather than nucleation) of the phenocryst phase. However, the suppression of bubble formation despite the accumulation of excluded volatiles is more difficult to explain but could be related to latent heat and difficulties in bubble formation in a restricted space. Finally, we flag complications in interpretations of embayment composition data due to element accumulation and bubble nucleation suppression.

The North Galactic Pole Rift and the Local Hot Bubble

NASA Technical Reports Server (NTRS)

Snowden, S. L.; Koutroumpa, D.; Kuntz, K. D.; Lallement, R.; Puspitarini, L.

2015-01-01

The North Galactic Pole Rift (NGPR) is one of the few distinct neutral hydrogen clouds at high Galactic latitudes that have well-defined distances. It is located at the edge of the Local Cavity (LC) and provides an important test case for understanding the Local Hot Bubble (LHB), the presumed location for the hot diffuse plasma responsible for much of the observed 1/4 keV emission originating in the solar neighborhood. Using data from the ROSAT All- Sky Survey and the Planck reddening map, we find the path length within the LC (LHB plus Complex of Local Interstellar Clouds) to be 98 plus or minus 27 pc, in excellent agreement with the distance to the NGPR of 98 +/- 6 pc. In addition, we examine another 14 directions that are distributed over the sky where the LC wall is apparently optically thick at 1/4 keV. We find that the data in these directions are also consistent with the LHB model and a uniform emissivity plasma filling most of the LC.

THE STRUCTURE OF THE LOCAL HOT BUBBLE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, W.; Galeazzi, M.; Uprety, Y.

Diffuse X-rays from the Local Galaxy ( DXL ) is a sounding rocket mission designed to quantify and characterize the contribution of Solar Wind Charge eXchange (SWCX) to the Diffuse X-ray Background and study the properties of the Local Hot Bubble (LHB). Based on the results from the DXL mission, we quantified and removed the contribution of SWCX to the diffuse X-ray background measured by the ROSAT All Sky Survey. The “cleaned” maps were used to investigate the physical properties of the LHB. Assuming thermal ionization equilibrium, we measured a highly uniform temperature distributed around kT  = 0.097 keV ± 0.013 keV (FWHM) ± 0.006more » keV (systematic). We also generated a thermal emission measure map and used it to characterize the three-dimensional (3D) structure of the LHB, which we found to be in good agreement with the structure of the local cavity measured from dust and gas.« less

Density-dependent regulation of growth of BSC-1 cells in cell culture: growth inhibitors formed by the cells.

PubMed Central

Holley, R W; Armour, R; Baldwin, J H

1978-01-01

Inhibitors formed by a monkey epithelial cell line, BSC-1, play an important role in limiting growth at high cell densities. At least three inhibitors are formed: lactic acid, ammonia, and an unidentified inhibitor that may be an unstable protein. The unidentified inhibitor is destroyed by shaking the conditioned medium, by bubbling gas through the medium, or by heating or storing the medium in the absence of cells. The concentrations of lactic acid and ammonia that accumulate in conditioned medium inhibit growth when added to fresh medium. These results, together with earlier studies, indicate that density-dependent regulation of growth of BSC-1 cells results from the combined effects of (a) inhibitors formed by the cells, (b) decreased availability of receptor sites for serum growth factors as the cells become crowded, and (c) limiting concentrations of low molecular weight nutrients in the medium. In contrast, density-dependent regulation of growth in 3T3 mouse embryo fibroblasts results almost entirely from inactivation of serum factors. PMID:273914

Bubble-generating nano-lipid carriers for ultrasound/CT imaging-guided efficient tumor therapy.

PubMed

Zhang, Nan; Li, Jia; Hou, Ruirui; Zhang, Jiangnan; Wang, Pei; Liu, Xinyang; Zhang, Zhenzhong

2017-12-20

Ideal therapeutic effectiveness of chemotherapy is obtained only when tumor cells are exposed to a maximal drug concentration, which is often hindered by dose-limiting toxicity. We designed a bubble-generating liposomal delivery system by introducing ammonium bicarbonate and gold nanorods into folic acid-conjugated liposomes to allow both multimodal imaging and the local release of drug (doxorubicin) with hyperthermia. The key component, ammonium bicarbonate, allows a controlled, rapid release of doxorubicin to provide an effective drug concentration in the tumor microenvironment. An in vitro temperature-triggered drug release study showed that cumulative release improved more than two-fold. In addition, in vitro and in vivo studies indicated that local heat treatment or ultrasonic cavitation enhanced the therapeutic efficiency greatly. The delivery system could also serve as an excellent contrast agent to allow ultrasonic imaging and computerized tomography imaging simultaneously to further achieve the aim of accurate diagnostics. Results of this study showed that this versatile bubble-generating liposome is a promising system to provide optimal therapeutic effects that are guided by multimodal imaging. Copyright © 2017 Elsevier B.V. All rights reserved.

Visualizing the Histotripsy Process: Bubble Cloud-Cancer Cell Interactions in a Tissue-Mimicking Environment.

PubMed

Vlaisavljevich, Eli; Maxwell, Adam; Mancia, Lauren; Johnsen, Eric; Cain, Charles; Xu, Zhen

2016-10-01

Histotripsy is a non-invasive ultrasonic ablation method that uses cavitation to mechanically fractionate tissue into acellular debris. With a sufficient number of pulses, histotripsy can completely fractionate tissue into a liquid-appearing homogenate with no cellular structures. The location, shape and size of lesion formation closely match those of the cavitation cloud. Previous work has led to the hypothesis that the rapid expansion and collapse of histotripsy bubbles fractionate tissue by inducing large stress and strain on the tissue structures immediately adjacent to the bubbles. In the work described here, the histotripsy bulk tissue fractionation process is visualized at the cellular level for the first time using a custom-built 2-MHz transducer incorporated into a microscope stage. A layer of breast cancer cells were cultured within an optically transparent fibrin-based gel phantom to mimic cells inside a 3-D extracellular matrix. To test the hypothesis, the cellular response to single and multiple histotripsy pulses was investigated using high-speed optical imaging. Bubbles were always generated in the extracellular space, and significant cell displacement/deformation was observed for cells directly adjacent to the bubble during both bubble expansion and collapse. The largest displacements were observed during collapse for cells immediately adjacent to the bubble, with cells moving more than 150-300 μm in less than 100 μs. Cells often underwent multiple large deformations (>150% strain) over multiple pulses, resulting in the bisection of cells multiple times before complete removal. To provide theoretical support to the experimental observations, a numerical simulation was conducted using a single-bubble model, which indicated that histotripsy exerts the largest strains and cell displacements in the regions immediately adjacent to the bubble. The experimental and simulation results support our hypothesis, which helps to explain the formation of the sharp lesions formed in histotripsy therapy localized to the regions directly exposed to the bubbles. Copyright © 2016 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

Quark Matter and Nuclear Collisions a Brief History of Strong Interaction Thermodynamics

NASA Astrophysics Data System (ADS)

Satz, Helmut

2012-08-01

The past 50 years have seen the emergence of a new field of research in physics, the study of matter at extreme temperatures and densities. The theory of strong interactions, quantum chromodynamics (QCD), predicts that in this limit, matter will become a plasma of deconfined quarks and gluons — the medium which made up the early universe in the first 10 microseconds after the Big Bang. High energy nuclear collisions are expected to produce short-lived bubbles of such a medium in the laboratory. I survey the merger of statistical QCD and nuclear collision studies for the analysis of strongly interacting matter in theory and experiment.

Solar Wind Charge Exchange and Local Hot Bubble X-Ray Emission with the DXL Sounding Rocket Experiment

NASA Technical Reports Server (NTRS)

Galeazzi, M.; Collier, M. R.; Cravens, T.; Koutroumpa, D.; Kuntz, K. D.; Lepri, S.; McCammon, D.; Porter, F. S.; Prasai, K.; Robertson, I.;

Midlatitude Plasma Bubbles Over China and Adjacent Areas During a Magnetic Storm on 8 September 2017

NASA Astrophysics Data System (ADS)

Aa, Ercha; Huang, Wengeng; Liu, Siqing; Ridley, Aaron; Zou, Shasha; Shi, Liqin; Chen, Yanhong; Shen, Hua; Yuan, Tianjiao; Li, Jianyong; Wang, Tan

2018-03-01

This paper presents observations of postsunset super plasma bubbles over China and adjacent areas during the second main phase of a storm on 8 September 2017. The signatures of the plasma bubbles can be seen or deduced from (1) deep field-aligned total electron content depletions embedded in regional ionospheric maps derived from dense Global Navigation Satellite System networks, (2) significant equatorial and midlatitudinal plasma bite-outs in electron density measurements on board Swarm satellites, and (3) enhancements of ionosonde virtual height and scintillation in local evening associated with strong southward interplanetary magnetic field. The bubbles/depletions covered a broad area mainly within 20°-45°N and 80°-110°E with bifurcated structures and persisted for nearly 5 hr (˜13-18 UT). One prominent feature is that the bubbles extended remarkably along the magnetic field lines in the form of depleted flux tubes, reaching up to midlatitude of around 50°N (magnetic latitude: 45.5°N) that maps to an altitude of 6,600 km over the magnetic equator. The maximum upward drift speed of the bubbles over the magnetic equator was about 700 m/s and gradually decreased with altitude and time. The possible triggering mechanism of the plasma bubbles was estimated to be storm time eastward prompt penetration electric field, while the traveling ionospheric disturbance could play a role in facilitating the latitudinal extension of the depletions.

Hidden Attractors in a Model of a Bubble Contrast Agent Oscillating Near an Elastic Wall

NASA Astrophysics Data System (ADS)

Garashchuk, Ivan; Sinelshchikov, Dmitry; Kudryashov, Nikolay

2018-02-01

A model describing the dynamics of a spherical gas bubble in a compressible viscous liquid is studied. The bubble is oscillating close to an elastic wall of finite thickness under the influence of an external pressure field which simulates a contrast agent oscillating close to a blood vessel wall. Here we investigate numerically the coexistence of chaotic and periodic attractors in this model. One of the tools applied for seeking coexisting attractors is the perpetual points method. This method can be helpful for localizing coexisting attractors, occurring in various physically realistic ranges of variation of the control parameters. We provide some examples of coexisting attractors to demonstrate the importance of the multistability problem for the applications.

Reactive Gas transport in soil: Kinetics versus Local Equilibrium Approach

NASA Astrophysics Data System (ADS)

Geistlinger, Helmut; Jia, Ruijan

2010-05-01

Gas transport through the unsaturated soil zone was studied using an analytical solution of the gas transport model that is mathematically equivalent to the Two-Region model. The gas transport model includes diffusive and convective gas fluxes, interphase mass transfer between the gas and water phase, and biodegradation. The influence of non-equilibrium phenomena, spatially variable initial conditions, and transient boundary conditions are studied. The objective of this paper is to compare the kinetic approach for interphase mass transfer with the standard local equilibrium approach and to find conditions and time-scales under which the local equilibrium approach is justified. The time-scale of investigation was limited to the day-scale, because this is the relevant scale for understanding gas emission from the soil zone with transient water saturation. For the first time a generalized mass transfer coefficient is proposed that justifies the often used steady-state Thin-Film mass transfer coefficient for small and medium water-saturated aggregates of about 10 mm. The main conclusion from this study is that non-equilibrium mass transfer depends strongly on the temporal and small-scale spatial distribution of water within the unsaturated soil zone. For regions with low water saturation and small water-saturated aggregates (radius about 1 mm) the local equilibrium approach can be used as a first approximation for diffusive gas transport. For higher water saturation and medium radii of water-saturated aggregates (radius about 10 mm) and for convective gas transport, the non-equilibrium effect becomes more and more important if the hydraulic residence time and the Damköhler number decrease. Relative errors can range up to 100% and more. While for medium radii the local equilibrium approach describes the main features both of the spatial concentration profile and the time-dependence of the emission rate, it fails completely for larger aggregates (radius about 100 mm). From the comparative study of relevant scenarios with and without biodegradation it can be concluded that, under realistic field conditions, biodegradation within the immobile water phase is often mass-transfer limited and the local equilibrium approach assuming instantaneous mass transfer becomes rather questionable. References Geistlinger, H., Ruiyan Jia, D. Eisermann, and C.-F. Stange (2008): Spatial and temporal variability of dissolved nitrous oxide in near-surface groundwater and bubble-mediated mass transfer to the unsaturated zone, J. Plant Nutrition and Soil Science, in press. Geistlinger, H. (2009) Vapor transport in soil: concepts and mathematical description. In: Eds.: S. Saponari, E. Sezenna, and L. Bonoma, Vapor emission to outdoor air and enclosed spaces for human health risk assessment: Site characterization, monitoring, and modeling. Nova Science Publisher. Milano. Accepted for publication.

A Mechanistic Study of Nucleate Boiling Under Microgravity Conditions

NASA Technical Reports Server (NTRS)

Dhir, V. K.; Warrier, G. R.; Hasan, M. M.

2002-01-01

The overall objective of this work is to study nucleate boiling heat transfer under microgravity conditions in such a way that while providing basic knowledge of the phenomena, it also leads to development of simulation models and correlations that can be used as design tools for a wide range of gravity levels. In the study a building block type of approach is used and both pool and low velocity flow boiling are investigated. Starting with experiments using a single bubble, the complexity of the experiments is increased to two or three inline bubbles, to five bubbles placed on a two-dimensional grid. Finally, experiments are conducted where a large number of prescribed cavities nucleate on the heater and when a commercial surface is used. So far experiments have been conducted at earth normal gravity and in the reduced gravity environment of the KC-135 aircraft whereas experiments on the space station are planned. Modeling/complete numerical simulation of the boiling process is an integral part of the total effort. Experiments conducted with single bubbles formed on a nucleation site microfabricated on a polished silicon wafer show that for gravity levels (g) varying from 1.5g(sub e) to 0.01g(sub e), the bubble diameter at departure varies approximately as (g(sub e)/g)(exp 1/2) and the growth period as (g(sub e)/g). When bubbles merge either inline or in a plane, the bubble diameter at departure is found to be smaller than that obtained for a single bubble and shows a weaker dependence on the level of gravity. The possible reason is that as the bubbles merge they create fluid circulation around the bubbles, which in turn induces a lift force that is responsible for the earlier departure of the bubbles. The verification of this proposition is being sought through numerical simulations. There is a merger of two inline, three inline, and several bubbles in a plane in the low gravity environment of the KC-135 aircraft. After merger and before departure, a mushroom type of bubble with several stems attached to the heater surface is clearly evident. Local heat fluxes during growth and departure of a single bubble were also measured. It was found that during most of the growth period of the bubble, generally the wall heat flux decreased with time because of the increased dry area under the bubble. However, the heat flux increased rapidly just prior to departure of the bubble because of the transient conduction into the cold liquid rushing to fill the space vacated by the bubble as the bubble base shrinks. The measured heat fluxes at various radial locations are found to be in qualitative agreement with the numerical predictions. Single bubble studies at earth normal gravity have also been performed on surfaces oriented at different angles to the gravitational acceleration with flow parallel to the surface. It is found that in all cases the bubbles slide along the surface before lift-off from the surface. The lift force generated as a result of the relative motion between the sliding bubbles and the imposed flow is found to play an important role when the normal force due to buoyancy is reduced. An experimental apparatus for the study of the bubble behavior with imposed flow under reduced gravity conditions has been developed and will soon be employed for experiments in the KC-135 aircraft.

Controllable bioeffects of laser-generated intracellular microbubbles

NASA Astrophysics Data System (ADS)

Zohdy, Marwa Joy

Laser-induced optical breakdown (LIOB) is a nonlinear energy absorption process that can generate precise damage in biological tissues. With femtosecond laser pulses, disruption is highly localized with minimal thermal and mechanical effects to the surrounding region. Cavitation bubbles are produced as a result of LIOB, and these bubbles can be detected and monitored with high-frequency ultrasound. In this work, the controllable viability effects of LIOB bubbles in single cells were characterized. Using a high-frequency acoustic transducer synchronized with a 793 nm, 100 fs laser pulsed at 250 kHz, thermal effects in the vicinity of an LIOB event were directly assessed. Temperaturedependent pulse-echo displacements were calculated using phase-sensitive correlation tracking and fit to a finite-element heat transfer model to estimate thermal distribution. Results indicate a minimal temperature increase (<1 degree C) within 100 microns of a bubble created with multiple laser pulses, confirming that LIOB can be controlled to be thermally noninvasive in the bubble vicinity. Acoustically detectable microbubbles were generated in individual cells with femtosecond LIOB. By adjusting laser fluence, exposure time, and focal location, LIOB could be controlled to produce distinctly different cellular effects. Small (1-2 micron) bubbles with short lifetimes (10100 ms) could be generated in cells without affecting their viability; and, alternatively, large (510 micron) bubbles with long lifetimes (1-5 s) could be generated for selective cell killing without affecting immediately neighboring cells. Experiments were performed in Chinese hamster ovary (CHO) cells in vitro, and LIOB was detected with both optical and acoustic microscopy. A long-term proliferation assay was also performed using green-fluorescent MCA207 mouse sarcoma cells targeted for LIOB. This assay confirmed that nondestructive bubbles did not affect target cell proliferation over several generations, and that destructive bubbles could indeed eliminate target cells and prevent further proliferation with no effect on immediately neighboring cells. These studies help to outline future applications for site-activated, acoustically monitored intracellular microbubbles. Nondestructive bubbles can potentially be used for functional cell measurements without introducing exogenous agents or affecting subsequent cell proliferation, and destructive bubbles can be used for highly precise biologically-targeted cancer cell therapy with real-time acoustic validation.

Design of an Improved Heater Array to Measure Microscale Wall Heat Transfer

NASA Technical Reports Server (NTRS)

Kim, Jungho; Chng, Choon Ping; Kalkur, T. S.

1996-01-01

An improved array of microscale heaters is being developed to measure the heat transfer coefficient at many points underneath individual bubbles during boiling as a function of space and time. This heater array enables the local heat transfer from a surface during the bubble growth and departure process to be measured with very high temporal and spatial resolution, and should allow better understanding of the boiling heat transfer mechanisms by pin-pointing when and where in the bubble departure cycle large amounts of wall heat transfer occur. Such information can provide much needed data regarding the important heat transfer mechanisms during the bubble departure cycle, and can serve as benchmarks to validate many of the analytical and numerical models used to simulate boiling. The improvements to the heater array include using a silicon-on-quartz substrate to reduce thermal cross-talk between the heaters, decreased space between the heaters, increased pad sizes on the heaters, and progressive heater sizes. Some results using the present heater array are discussed.

Allostery through protein-induced DNA bubbles

DOE PAGES

Traverso, Joseph J.; Manoranjan, Valipuram S.; Bishop, A. R.; ...

2015-03-12

Allostery through DNA is increasingly recognized as an important modulator of DNA functions. Here, we show that the coalescence of protein-induced DNA bubbles can mediate allosteric interactions that drive protein aggregation. We propose that such allostery may regulate DNA's flexibility and the assembly of the transcription machinery. Mitochondrial transcription factor A (TFAM), a dual-function protein involved in mitochondrial DNA (mtDNA) packaging and transcription initiation, is an ideal candidate to test such a hypothesis owing to its ability to locally unwind the double helix. Numerical simulations demonstrate that the coalescence of TFAM-induced bubbles can explain experimentally observed TFAM oligomerization. The resultingmore » melted DNA segment, approximately 10 base pairs long, around the joints of the oligomers act as flexible hinges, which explains the efficiency of TFAM in compacting DNA. Since mitochondrial polymerase (mitoRNAP) is involved in melting the transcription bubble, TFAM may use the same allosteric interaction to both recruit mitoRNAP and initiate transcription.« less

Noise analysis of nucleate boiling

NASA Technical Reports Server (NTRS)

Mcknight, R. D.; Ram, K. S.

1971-01-01

The techniques of noise analysis have been utilized to investigate nucleate pool boiling. A simple experimental setup has been developed for obtaining the power spectrum of a nucleate boiling system. These techniques were first used to study single bubbles, and a method of relating the two-dimensional projected size and the local velocity of the bubbles to the auto-correlation functions is presented. This method is much less time consuming than conventional methods of measurement and has no probes to disturb the system. These techniques can be used to determine the contribution of evaporation to total heat flux in nucleate boiling. Also, these techniques can be used to investigate the effect of various parameters upon the frequency response of nucleate boiling. The predominant frequencies of the power spectrum correspond to the frequencies of bubble generation. The effects of heat input, degree of subcooling, and liquid surface tension upon the power spectra of a boiling system are presented. It was found that the degree of subcooling has a more pronounced effect upon bubble size than does heat flux. Also the effect of lowering surface tension can be sufficient to reduce the effect of the degree of subcooling upon the size of the bubbles.

The effect of air bubbles on rabbit blood brain barrier.

PubMed

Hjelde, A; Bolstad, G; Brubakk, A O

2002-01-01

Several investigators have claimed that the blood brain barrier (BBB) may be broken by circulating bubbles, resulting in brain tissue edema. The aim of this study was to examine the effect of air bubbles on the permeability of BBB. Three groups of 6 rabbits were infused an isoosmotic solution of NaCl w/macrodex and 1% Tween. The solution was saturated with air bubbles and infused at rates of 50-100 ml hr(-1), a total of 1.6, 3.3, or 6.6 ml in each group, respectively. Two groups, each consisting of 6 rabbits, served as controls; one was infused by a degassed isoosmotic NaCl solution and one was sham-operated. All animals were left for 30 min before they were sacrificed. Specific gravity of brain tissue samples was determined using a brombenzene/kerosene gradient column, where a decrease in specific gravity indicates local brain edema. Specific gravity was significantly lower for left (P = 0.037) and right (P = 0.012) hemisphere white matter and left (P = 0.0015) and right (P = 0.002) hemisphere gray matter for the bubble-infused animals compared to the sham-operated ones. Infusion of degassed NaCl solution alone affected white left (P= 0.011) and right (P= 0.013), but not gray matter of both hemispheres. We speculate that insufficient degassing of the fluid may cause the effect of NaCl solution on the BBB of the white matter, indicating that the vessels of the white matter are more sensitive to gas bubbles than gray matter. Increasing the number of infused bubbles had no further impact on the development of cerebral edema, indicating that a threshold value was reached already at the lowest concentration of bubbles.

Convective mass transfer around a dissolving bubble

NASA Astrophysics Data System (ADS)

Duplat, Jerome; Grandemange, Mathieu; Poulain, Cedric

2017-11-01

Heat or mass transfer around an evaporating drop or condensing vapor bubble is a complex issue due to the interplay between the substrate properties, diffusion- and convection-driven mass transfer, and Marangoni effects, to mention but a few. In order to disentangle these mechanisms, we focus here mainly on the convective mass transfer contribution in an isothermal mass transfer problem. For this, we study the case of a millimetric carbon dioxide bubble which is suspended under a substrate and dissolved into pure liquid water. The high solubility of CO2 in water makes the liquid denser and promotes a buoyant-driven flow at a high (solutal) Rayleigh number (Ra˜104 ). The alteration of p H allows the concentration field in the liquid to be imaged by laser fluorescence enabling us to measure both the global mass flux (bubble volume, contact angle) and local mass flux around the bubble along time. After a short period of mass diffusion, where the boundary layer thickens like the square root of time, convection starts and the CO2 is carried by a plume falling at constant velocity. The boundary layer thickness then reaches a plateau which depends on the bubble cross section. Meanwhile the plume velocity scales like (dV /d t )1 /2 with V being the volume of the bubble. As for the rate of volume loss, we recover a constant mass flux in the diffusion-driven regime followed by a decrease in the volume V like V2 /3 after convection has started. We present a model which agrees well with the bubble dynamics and discuss our results in the context of droplet evaporation, as well as high Rayleigh convection.

Gas embolotherapy: Bubble evolution in acoustic droplet vaporization and design of a benchtop microvascular model

NASA Astrophysics Data System (ADS)

Wong, Zheng Zheng

This work was motivated by an ongoing development of a potential embolotherapy technique to occlude blood flow to tumors using gas bubbles selectively formed by in vivo acoustic droplet vaporization (ADV) of liquid perfluorocarbon droplets. Mechanisms behind the ADV, transport and lodging of emboli need to be understood before gas embolotherapy can translate to the clinic. Evolution of a bubble from acoustic droplet vaporization in a rigid tube, under physiological and room temperature conditions, was observed via ultra-high speed imaging. Effective radii and radial expansion ratios were obtained by processing the images using Image] software. At physiological temperature, a radial expansion ratio of 5.05 was attained, consistent with theoretical prediction. The initial radial growth rate was linear, after which the growth rate increased proportionally with square root of time. Nondimensionalization revealed that the subsequent growth rate also varied inversely with square root of initial radius. Eventually growth became asymptotic. No collapse was observed. A theoretical model derived from a modified Bernoulli equation, and a computational model by Ye & Bull (2004), were compared respectively with experimental results. Initial growth rates were predicted correctly by both models. Experimental results showed heavy damping of growth rate as the bubble grew towards the wall, whereas both models predicted an overshoot in growth followed by multiple oscillations. The theoretical model broke down near the wall; the computational model gave a reasonable bubble shape near the wall but would require correct initial pressure values to be accurate. At room temperature, the expansion ratio shot to 1.43 initially and oscillated down to 1.11, far below the theoretical prediction. Failure of the bubble to expand fully could be due to unconsumed or condensed liquid perfluorocarbon. A new fabrication method via non-lithographic means was devised to make a circular-lumen microchannel out of PDMS, with a diameter as small as 80 microns to mimic the size of a medium arteriole. The microchannel was endothelialized successfully, with a fairly homogeneous distribution along the length. Cell viability assays confirmed the viability of cells maintained in the microchannel. Bubble motion experiments performed with the benchtop microvascular model demonstrated its feasibility.

Singular effective slip length for longitudinal flow over a dense bubble mattress

NASA Astrophysics Data System (ADS)

Schnitzer, Ory

2016-09-01

We consider the effective hydrophobicity of a periodically grooved surface immersed in liquid, with trapped shear-free bubbles protruding between the no-slip ridges at a π /2 contact angle. Specifically, we carry out a singular-perturbation analysis in the limit ɛ ≪1 where the bubbles are closely spaced, finding the effective slip length (normalized by the bubble radius) for longitudinal flow along the ridges as π /√{2 ɛ }-(12 /π ) ln2 +(13 π /24 ) √{2 ɛ }+o (√{ɛ }) , the small parameter ɛ being the planform solid fraction. The square-root divergence highlights the strong hydrophobic character of this configuration; this leading singular term (along with the third term) follows from a local lubrication-like analysis of the gap regions between the bubbles, together with general matching considerations and a global conservation relation. The O (1 ) constant term is found by matching with a leading-order solution in the outer region, where the bubbles appear to be touching. We find excellent agreement between our slip-length formula and a numerical scheme recently derived using a unified-transform method [Crowdy, IMA J. Appl. Math. 80, 1902 (2015), 10.1093/imamat/hxv019]. The comparison demonstrates that our asymptotic formula, together with the diametric dilute-limit approximation [Crowdy, J. Fluid Mech. 791, R7 (2016), 10.1017/jfm.2016.88], provides an elementary analytical description for essentially arbitrary no-slip fractions.

Modelling of Lyman-alpha emitting galaxies and ionized bubbles at the epoch of reionization

NASA Astrophysics Data System (ADS)

Yajima, Hidenobu; Sugimura, Kazuyuki; Hasegawa, Kenji

2018-07-01

Understanding {Ly{α}} emitting galaxies (LAEs) can be a key to reveal cosmic reionization and galaxy formation in the early Universe. Based on halo merger trees and {Ly{α}} radiation transfer calculations, we model redshift evolution of LAEs and their observational properties at z ≥ 6. We consider ionized bubbles associated with individual LAEs and IGM (integer-galactic medium) transmission of {Ly{α}} photons. We find that {Ly{α}} luminosity tightly correlates with halo mass and stellar mass, while the relation with star formation rate has a large dispersion. Comparing our models with the observed luminosity function by Konno et al., we suggest that LAEs at z ˜ 7 have galactic wind of V_out ≳ 100 km s^{-1} and H I column density of N_HI ≳ 10^{20} cm^{-2}. Number density of bright LAEs rapidly decreases as redshift increases, due to both lower star formation rate and smaller H II bubbles. Our model predicts future wide deep surveys with next-generation telescopes, such as James Webb Space Telescope, European Extremely Large Telescope, and Thirty Metre Telescope, can detect LAEs at z ˜ 10 with a number density of n_LAE ˜ {a few } × 10^{-6} Mpc^{-3} for the flux sensitivity of 10^{-18} erg cm^{-2} s^{-1}. When giant H II bubbles are formed by clustering LAEs, the number density of observable LAEs can increase by a factor of few. By combining these surveys with future 21-cm observations, it could be possible to detect both LAEs with L_{Lyα }≳ 10^{42} erg s^{-1} and their associated giant H II bubbles with the size {≳ } 250 kpc at z ˜ 10.

Apparatus for localizing disturbances in pressurized water reactors (PWR)

DOEpatents

Sykora, Dalibor

1989-01-01

The invention according to CS-PS 177386, entitled ''Apparatus for increasing the efficiency and passivity of the functioning of a bubbling-vacuum system for localizing disturbances in nuclear power plants with a pressurized water reactor'', concerns an important area of nuclear power engineering that is being developed in the RGW member countries. The invention solves the problems of increasing the reliability and intensification during the operation of the above very important system for guaranteeing the safety of the standard nuclear power plants of Soviet design. The essence of the invention consists in the installation of a simple passively operating supplementary apparatus. Consequently, the following can be observed in the system: first an improvement and simultaneous increase in the reliability of its function during the critical transition period, which follows the filling of the second space with air from the first space; secondly, elimination of the hitherto unavoidable initiating role of the active sprinkler-condensation device present; thirdly, a more effective performance and subjection of the elements to disintegration of the water flowing from the bubbling condenser into the first space; and fourthly, an enhanced utilization of the heat-conducting ability of the water reservoir of the bubbling condenser. Representatives of the supplementary apparatus are autonomous and local secondary systems of the sprinkler-sprayer without an insert, which spray the water under the effect of gravity. 1 fig.

Carbon-catalyzed oxidation of SO2 by NO2 and air

NASA Technical Reports Server (NTRS)

Rogowski, R. S.; Schryer, D. R.; Cofer, W. R., III; Edahl, R. A., Jr.; Munavalli, S.

1982-01-01

A series of experiments was performed using carbon particles (commercial furnace black) as a surrogate for soot particles. Carbon particles were suspended in water, and gas mixtures were bubbled into the suspensions to observe the effect of carbon particles on the oxidation of SO2 by air and NO2. Identical gas mixtures were bubbled into a blank containing only pure water. After exposure each solution was analyzed for pH and sulfate. It was found that NO2 greatly enhances the oxidation of SO2 to sulfate in the presence of carbon particles. The amount of sulfate found in the blanks was significantly less. Under the conditions of these experiments no saturation of the reaction was observed and SO2 was converted to sulfate even in a highly acid medium (pH or = 1.5).

Oxidation of SO2 by NO2 and air in an aqueous suspension of carbon

NASA Technical Reports Server (NTRS)

Rogowski, R. S.; Schryer, D. R.; Cofer, W. R., III; Edahl, R. A., Jr.; Munavalli, S.

1982-01-01

A series of experiments has been performed using carbon black as a surrogate for soot particles. Carbon black was suspended in water and gas mixtures were bubbled into the suspensions to observe the effect of carbon particles on the oxidation of SO2 by air and NO2. Identical gas mixtures were bubbled into a black containing only pure water. After exposure each solution was analyzed for pH and sulfate. It was found that NO2 greatly enhances the oxidation of SO2 to sulfate in the presence of carbon black. The amount of sulfate in the blanks was significantly less. Under the conditions of the experiments no saturation of the reaction was observed and SO2 was converted to sulfate even in a highly acid medium (pH not less than 1.5).

Influence of the elastic deformation of a foam on its mobility in channels of linearly varying width.

PubMed

Dollet, Benjamin; Jones, Siân A; Méheust, Yves; Cantat, Isabelle

2014-08-01

We study foam flow in an elementary model porous medium consisting of a convergent and a divergent channel positioned side by side and possessing a fixed joint porosity. Configurations of converging or diverging channels are ubiquitous at the pore scale in porous media, as all channels linking pores possess a converging and diverging part. The resulting flow kinematics imposes asymmetric bubble deformations in the two channels, which modulate foam-wall friction and strongly impact the flux distribution. We measure, as well as quantitatively predict, the ratio of the fluxes in the two channels as a function of the channel widths by modeling pressure drops of both viscous and capillary origins. This study reveals the crucial importance of boundary-induced bubble deformation on the mobility of a flowing foam, resulting in particular in flow irreversibility.

Rotation measure synthesis at the 2 m wavelength of the FAN region: unveiling screens and bubbles

NASA Astrophysics Data System (ADS)

Iacobelli, M.; Haverkorn, M.; Katgert, P.

2013-01-01

Context. Rotation measure synthesis of the Westerbork Synthesis Radio Telescope (WSRT) observations at λ ~ 2 m of the FAN region at l = 137°, b = +7° shows the morphology of structures in the ionized interstellar medium. Aims: We interpret the diffuse polarized synchrotron emission in terms of coherent structures in the interstellar medium and the properties of the interstellar magnetic field. Methods: We performed statistical analysis of the polarization data cube obtained through rotation measure synthesis. For the first time, cross-correlation is applied to identify and characterize polarized structures in Faraday depth space. Complementary information about the medium are derived from Hα emission, properties of nearby pulsars, and optical polarized starlight measurements. Results: We find an overall asymmetric Faraday dispersion function in a Faraday depth range of [-13, +5] rad m-2, which is peaked around -1 rad m-2. Three morphological patterns are recognized, showing structures on scales from degrees down to the beam size. The first structure is a nearby synchrotron emission component with low Faraday depth, filling the entire field of view. The second pattern is a circular polarization structure with enhanced (negative) Faraday depth, which has the same morphology as a low-emission region within the third component. This third component is interpreted as the background in which the circular structure is embedded. At low Faraday depth values, a low gradient across the imaged field is detected, almost aligned with the Galactic plane. Power spectra of polarized structures in Faraday depth space provide evidence of turbulence. Conclusions: A sign reversal in Faraday depth from the nearby component to the circular component indicates a reversal of the magnetic field component along the line of sight, from towards the observer and nearby to away from the observer at large distances. The distance to the nearby, extended component is estimated as ≲100 pc, which suggests that this structure corresponds to the Local Bubble wall. For the circular component, various physical interpretations are discussed. The most likely explanation is that the circular component seems to be the presence of a nearby (~200 pc away) relic Strömgren sphere, associated with an old unidentified white dwarf star and expanding in a low-density environment. Faraday rotation datacubes are only available at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/549/A56

Nanobubbles: a new paradigm for air-seeding in xylem.

PubMed

Schenk, H Jochen; Steppe, Kathy; Jansen, Steven

2015-04-01

Long-distance water transport in plants relies on a system that typically operates under negative pressure and is prone to hydraulic failure due to gas bubble formation. One primary mechanism of bubble formation takes place at nanoporous pit membranes between neighboring conduits. We argue that this process is likely to snap off nanobubbles because the local increase in liquid pressure caused by entry of air-water menisci into the complex pit membrane pores would energetically favor nanobubble formation over instant cavitation. Nanobubbles would be stabilized by surfactants and by gas supersaturation of the sap, may dissolve, fragment into smaller bubbles, or create embolisms. The hypothesis that safe and stable nanobubbles occur in plants adds a new component supporting the cohesion-tension theory. Copyright © 2015 Elsevier Ltd. All rights reserved.

Ultrasound in Enzyme Activation and Inactivation

NASA Astrophysics Data System (ADS)

Mawson, Raymond; Gamage, Mala; Terefe, Netsanet Shiferaw; Knoerzer, Kai

As discussed in previous chapters, most effects due to ultrasound arise from cavitation events, in particular, collapsing cavitation bubbles. These collapsing bubbles generate very high localized temperatures and pressure shockwaves along with micro-streaming that is associated with high shear forces. These effects can be used to accelerate the transport of substrates and reaction products to and from enzymes, and to enhance mass transfer in enzyme reactor systems, and thus improve efficiency. However, the high velocity streaming, together with the formation of hydroxy radicals and heat generation during collapsing of bubbles, may also potentially affect the biocatalyst stability, and this can be a limiting factor in combined ultrasound/enzymatic applications. Typically, enzymes can be readily denatured by slight changes in environmental conditions, including temperature, pressure, shear stress, pH and ionic strength.

On the Distribution of Ion Density Depletion Along Magnetic Field Lines as Deduced Using C-NOFS

NASA Technical Reports Server (NTRS)

Dao, E.; Kelley, M. C.; Hysell, D. L.; Retterer, J. M.; Su, Y.-J.; Pfaff, Robert F.; Roddy, P. A.; Ballenthin, J. O.

2012-01-01

To investigate ion density depletion along magnetic field lines, we compare in situ-measured ion density fluctuations as seen from C/NOFS and compare them to the field-line-integrated depletion of the whole bubble as inferred from electric field measurements. Results show that, within C/NOFS' range, local measurement of the normalized density depletion, (Delta)n/n(sub 0), near the apex may be far less than at other points on the same field line. We argue that the distribution of (Delta)n/n(sub 0) is a weighted distribution concentrated at latitudes of the Appleton anomalies and becomes more heavily weighted the closer the field-aligned bubble rises to the peak of the anomalies. A three-dimensional simulation of an ionospheric bubble verifies our arguments.

Liquid Nitrogen as Fast High Voltage Switching Medium

NASA Astrophysics Data System (ADS)

Dickens, J.; Neuber, A.; Haustein, M.; Krile, J.; Krompholz, H.

2002-12-01

Compact pulsed power systems require new switching technologies. For high voltages, liquid nitrogen seems to be a suitable switching medium, with high hold-off voltage, low dielectric constant, and no need for pressurized systems as in high pressure gas switches. The discharge behavior in liquid nitrogen, such as breakdown voltages, formative times, current rise as function of voltage, recovery, etc. are virtually unknown, however. The phenomenology of breakdown in liquid nitrogen is investigated with high speed (temporal resolution < 1 ns) electrical and optical diagnostics, in a coaxial system with 50-Ohm impedance. Discharge current and voltage are determined with transmission line type current sensors and capacitive voltage dividers. The discharge luminosity is measured with photomultiplier tubes. Preliminary results of self-breakdown investigations (gap 1 mm, breakdown voltage 44 kV, non-boiling supercooled nitrogen) show a fast (2 ns) transition from an unknown current level to several mA, a long-duration (100 ns) phase with constant current superimposed by ns-spikes, and a final fast transition to the impedance limited current during several nanoseconds. The optical measurements will be expanded toward spectroscopy and high speed photography with the aim of clarifying the overall breakdown mechanisms, including electronic initiation, bubble formation, bubble dynamics, and their role in breakdown, for different electrode geometries (different macroscopic field enhancements).

Physics of beer tapping.

PubMed

Rodríguez-Rodríguez, Javier; Casado-Chacón, Almudena; Fuster, Daniel

2014-11-21

The popular bar prank known in colloquial English as beer tapping consists in hitting the top of a beer bottle with a solid object, usually another bottle, to trigger the foaming over of the former within a few seconds. Despite the trick being known for a long time, to the best of our knowledge, the phenomenon still lacks scientific explanation. Although it seems natural to think that shock-induced cavitation enhances the diffusion of CO2 from the supersaturated bulk liquid into the bubbles by breaking them up, the subtle mechanism by which this happens remains unknown. Here, we show that the overall foaming-over process can be divided into three stages where different physical phenomena take place in different time scales: namely, the bubble-collapse (or cavitation) stage, the diffusion-driven stage, and the buoyancy-driven stage. In the bubble-collapse stage, the impact generates a train of expansion-compression waves in the liquid that leads to the fragmentation of preexisting gas cavities. Upon bubble fragmentation, the sudden increase of the interface-area-to-volume ratio enhances mass transfer significantly, which makes the bubble volume grow by a large factor until CO2 is locally depleted. At that point buoyancy takes over, making the bubble clouds rise and eventually form buoyant vortex rings whose volume grows fast due to the feedback between the buoyancy-induced rising speed and the advection-enhanced CO2 transport from the bulk liquid to the bubble. The physics behind this explosive process sheds insight into the dynamics of geological phenomena such as limnic eruptions.

TEM characterization of irradiated U-7Mo/Mg dispersion fuel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gan, J.; Keiser, D. D.; Miller, B. D.

This paper presents the results of transmission electron microscopy (TEM) characterization on neutron-irradiated samples taken from the low-flux and high-flux sides of the same fuel plate with U-7Mo fuel particles dispersed in Mg matrix with aluminum alloy Al6061 as cladding material that was irradiated edge-on to the core in the Advanced Test Reactor. The corresponding local fission density and fission rate of the fuel particles and the average fuel-plate centerline temperature for the low-flux and high-flux samples are estimated to be 3.7 × 10 21 f/cm 3, 7.4 × 10 14 f/cm 3/s and 123 °C, and 5.5 × 10more » 21 f/cm3, 11.0 × 10 14 f/cm 3/s and 158 °C, respectively. Complex interaction layers developed at the Al-Mg interface, consisting of Al 3Mg 2 and Al 12Mg 17 along with precipitates of MgO, Mg 2Si and FeAl 5.3. No interaction between Mg matrix and U-Mo fuel particle was identified. For the U-Mo fuel particles, at low fission density, small elongated bubbles wrapped around the clean areas with a fission gas bubble superlattice, which suggests that bubble coalescence is an important mechanism for converting the fission gas bubble superlattice to large bubbles. At high fission density, no bubbles or porosity were observed in the Mg matrix, and pockets of residual fission gas bubble superlattice were observed in the U-Mo fuel particle interior.« less

TEM characterization of irradiated U-7Mo/Mg dispersion fuel

DOE PAGES

Gan, J.; Keiser, D. D.; Miller, B. D.; ...

2017-07-15

This paper presents the results of transmission electron microscopy (TEM) characterization on neutron-irradiated samples taken from the low-flux and high-flux sides of the same fuel plate with U-7Mo fuel particles dispersed in Mg matrix with aluminum alloy Al6061 as cladding material that was irradiated edge-on to the core in the Advanced Test Reactor. The corresponding local fission density and fission rate of the fuel particles and the average fuel-plate centerline temperature for the low-flux and high-flux samples are estimated to be 3.7 × 10 21 f/cm 3, 7.4 × 10 14 f/cm 3/s and 123 °C, and 5.5 × 10more » 21 f/cm3, 11.0 × 10 14 f/cm 3/s and 158 °C, respectively. Complex interaction layers developed at the Al-Mg interface, consisting of Al 3Mg 2 and Al 12Mg 17 along with precipitates of MgO, Mg 2Si and FeAl 5.3. No interaction between Mg matrix and U-Mo fuel particle was identified. For the U-Mo fuel particles, at low fission density, small elongated bubbles wrapped around the clean areas with a fission gas bubble superlattice, which suggests that bubble coalescence is an important mechanism for converting the fission gas bubble superlattice to large bubbles. At high fission density, no bubbles or porosity were observed in the Mg matrix, and pockets of residual fission gas bubble superlattice were observed in the U-Mo fuel particle interior.« less

Buoyancy effects in steeply inclined air-water bubbly shear flow in a rectangular channel

NASA Astrophysics Data System (ADS)

Sanaullah, K.; Arshad, M.; Khan, A.; Chughtai, I. R.

2015-07-01

We report measurements of two-dimensional ( B/ D = 5) fully turbulent and developed duct flows (overall length/depth, L/ D = 60; D-based Reynolds number Re > 104) for inclinations to 30° from vertical at low voidages (< 5 % sectional average) representative of disperse regime using tap water bubbles (4-6 mm) and smaller bubbles (2 mm) stabilised in ionic solution. Pitot and static probe instrumentation, primitive but validated, provided adequate (10 % local value) discrimination of main aspects of the mean velocity and voidage profiles at representative streamwise station i.e L/ D = 40. Our results can be divided into three categories of behaviour. For vertical flow (0°) the evidence is inconclusive as to whether bubbles are preferentially trapped within the wall-layer as found in some, may be most earlier experimental works. Thus, the 4-mm bubbles showed indication of voidage retention but the 2-mm bubbles did not. For nearly vertical flow (5°) there was pronounced profiling of voidage especially with 4-mm bubbles but the transverse transport was not suppressed sufficiently to induce any obvious layering. In this context, we also refer to similarities with previous work on one-phase vertical and nearly vertical mixed convection flows displaying buoyancy inhibited mean shear turbulence. However, with inclined flow (10+ degrees) a distinctively layered pattern was invariably manifested in which voidage confinement increased with increasing inclination. In this paper we address flow behavior at near vertical conditions. Eulerian, mixed and VOF models were used to compute voidage and mean velocity profiles.

Ultrasonic bubbles in medicine: influence of the shell.

PubMed

Postema, Michiel; Schmitz, Georg

2007-04-01

Ultrasound contrast agents consist of microscopically small bubbles encapsulated by an elastic shell. These microbubbles oscillate upon ultrasound insonification, and demonstrate highly nonlinear behavior, ameliorating their detectability. (Potential) medical applications involving the ultrasonic disruption of contrast agent microbubble shells include release-burst imaging, localized drug delivery, and noninvasive blood pressure measurement. To develop and enhance these techniques, predicting the cracking behavior of ultrasound-insonified encapsulated microbubbles has been of importance. In this paper, we explore microbubble behavior in an ultrasound field, with special attention to the influence of the bubble shell. A bubble in a sound field can be considered a forced damped harmonic oscillator. For encapsulated microbubbles, the presence of a shell has to be taken into account. In models, an extra damping parameter and a shell stiffness parameter have been included, assuming that Hooke's Law holds for the bubble shell. At high acoustic amplitudes, disruptive phenomena have been observed, such as microbubble fragmentation and ultrasonic cracking. We analyzed the occurrence of ultrasound contrast agent fragmentation, by simulating the oscillating behavior of encapsulated microbubbles with various sizes in a harmonic acoustic field. Fragmentation occurs exclusively during the collapse phase and occurs if the kinetic energy of the collapsing microbubble is greater than the instantaneous bubble surface energy, provided that surface instabilities have grown big enough to allow for break-up. From our simulations it follows that the Blake critical radius is not a good approximation for a fragmentation threshold. We demonstrated how the phase angle differences between a damped radially oscillating bubble and an incident sound field depend on shell parameters.

Physics of Beer Tapping

NASA Astrophysics Data System (ADS)

Rodríguez-Rodríguez, Javier; Casado-Chacón, Almudena; Fuster, Daniel

2014-11-01

The popular bar prank known in colloquial English as beer tapping consists in hitting the top of a beer bottle with a solid object, usually another bottle, to trigger the foaming over of the former within a few seconds. Despite the trick being known for a long time, to the best of our knowledge, the phenomenon still lacks scientific explanation. Although it seems natural to think that shock-induced cavitation enhances the diffusion of CO2 from the supersaturated bulk liquid into the bubbles by breaking them up, the subtle mechanism by which this happens remains unknown. Here, we show that the overall foaming-over process can be divided into three stages where different physical phenomena take place in different time scales: namely, the bubble-collapse (or cavitation) stage, the diffusion-driven stage, and the buoyancy-driven stage. In the bubble-collapse stage, the impact generates a train of expansion-compression waves in the liquid that leads to the fragmentation of preexisting gas cavities. Upon bubble fragmentation, the sudden increase of the interface-area-to-volume ratio enhances mass transfer significantly, which makes the bubble volume grow by a large factor until CO2 is locally depleted. At that point buoyancy takes over, making the bubble clouds rise and eventually form buoyant vortex rings whose volume grows fast due to the feedback between the buoyancy-induced rising speed and the advection-enhanced CO2 transport from the bulk liquid to the bubble. The physics behind this explosive process sheds insight into the dynamics of geological phenomena such as limnic eruptions.

A non-local free boundary problem arising in a theory of financial bubbles

PubMed Central

Berestycki, Henri; Monneau, Regis; Scheinkman, José A.

2014-01-01

We consider an evolution non-local free boundary problem that arises in the modelling of speculative bubbles. The solution of the model is the speculative component in the price of an asset. In the framework of viscosity solutions, we show the existence and uniqueness of the solution. We also show that the solution is convex in space, and establish several monotonicity properties of the solution and of the free boundary with respect to parameters of the problem. To study the free boundary, we use, in particular, the fact that the odd part of the solution solves a more standard obstacle problem. We show that the free boundary is and describe the asymptotics of the free boundary as c, the cost of transacting the asset, goes to zero. PMID:25288815

HOW SIGNIFICANT IS RADIATION PRESSURE IN THE DYNAMICS OF THE GAS AROUND YOUNG STELLAR CLUSTERS?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Silich, Sergiy; Tenorio-Tagle, Guillermo, E-mail: silich@inaoep.mx

2013-03-01

The impact of radiation pressure on the dynamics of the gas in the vicinity of young stellar clusters is thoroughly discussed. The radiation over the thermal/ram pressure ratio time evolution is calculated explicitly and the crucial roles of the cluster mechanical power, the strong time evolution of the ionizing photon flux, and the bolometric luminosity of the exciting cluster are stressed. It is shown that radiation has only a narrow window of opportunity to dominate the wind-driven shell dynamics. This may occur only at early stages of the bubble evolution and if the shell expands into a dusty and/or amore » very dense proto-cluster medium. The impact of radiation pressure on the wind-driven shell always becomes negligible after about 3 Myr. Finally, the wind-driven model results allow one to compare the model predictions with the distribution of thermal pressure derived from X-ray observations. The shape of the thermal pressure profile then allows us to distinguish between the energy and the momentum-dominated regimes of expansion and thus conclude whether radiative losses of energy or the leakage of hot gas from the bubble interior have been significant during bubble evolution.« less

Comments on the possibility of cavitation in liquid metal targets for pulsed spallation neutron sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carpenter J.M.

When short pulses of protons strike the volume of a liquid target, the rapid heating produces a pressurized region which relaxes as the pressure wave propagates outward. Skala and Bauer have modeled the effects of the pressure wave impinging on the container walls of a liquid mercury target under ESS conditions. They find that high pressures and high wall stresses result if the medium is uniform, nearly incompressible liquid. The pressure and the stresses are much reduced if the liquid contains bubbles of helium, due to their high compressibility. However, according to the calculation, the pressure still reaches an atmospheremore » or so at the surface, which reflects the compressive wave as a rarefaction wave of the same magnitude. Even such modest underpressures can lead to the growth of bubbles (cavitation) at or near the surface, which can collapse violently and erode the container surface. It is necessary to avoid this. Leighton provides a wide ranging discussion of pressure waves in bubbly media, which may provide insights into the nature and control of cavitation phenomena. The paper surveys some of the relevant information from that source.« less

On the mechanism of pulsed laser ablation of phthalocyanine nanoparticles in an aqueous medium

NASA Astrophysics Data System (ADS)

Kogan, Boris; Malimonenko, Nicholas; Butenin, Alexander; Novoseletsky, Nicholas; Chizhikov, Sergei

2018-06-01

Laser ablation of phthalocyanine nanoparticles has potential for cancer treatment. The ablation is accompanied by the formation of microbubbles and the sublimation of nanoparticles. This was investigated in a liquid medium simulating tissue using optical-acoustic and spectral-luminescent methods. The thresholds for the appearance of microbubbles have been determined as a function of nanoparticle size. For the minimal size particles (80 nm) this threshold is equal to about 20–25 mJ cm‑2 and for the maximal size particles (230 nm) this threshold is equal to about 7 mJ cm‑2. It was estimated that the particle temperature at which bubbles arise is near 145 °С.

Bubble Generation in a Flowing Liquid Medium and Resulting Two-Phase Flow in Microgravity

NASA Technical Reports Server (NTRS)

Pais, S. C.; Kamotani, Y.; Bhunia, A.; Ostrach, S.

1999-01-01

The present investigation reports a study of bubble generation under reduced gravity conditions, using both a co-flow and a cross-flow configuration. This study may be used in the conceptual design of a space-based thermal management system. Ensuing two-phase flow void fraction can be accurately monitored using a single nozzle gas injection system within a continuous liquid flow conduit, as utilized in the present investigation. Accurate monitoring of void fraction leads to precise control of heat and mass transfer coefficients related to a thermal management system; hence providing an efficient and highly effective means of removing heat aboard spacecraft or space stations. Our experiments are performed in parabolic flight aboard the modified DC-9 Reduced Gravity Research Aircraft at NASA Lewis Research Center, using an air-water system. For the purpose of bubble dispersion in a flowing liquid, we use both a co-flow and a cross-flow configuration. In the co-flow geometry, air is introduced through a nozzle in the same direction with the liquid flow. On the other hand, in the cross-flow configuration, air is injected perpendicular to the direction of water flow, via a nozzle protruding inside the two-phase flow conduit. Three different flow conduit (pipe) diameters are used, namely, 1.27 cm, 1.9 cm and 2.54 cm. Two different ratios of nozzle to pipe diameter (D(sub N))sup * are considered, namely (D(sub N))sup * = 0.1 and 0.2, while superficial liquid velocities are varied from 8 to 70 cm/s depending on flow conduit diameter. It is experimentally observed that by holding all other flow conditions and geometry constant, generated bubbles decrease in size with increase in superficial liquid velocity. Detached bubble diameter is shown to increase with air injection nozzle diameter. Likewise, generated bubbles grow in size with increasing pipe diameter. Along the same lines, it is shown that bubble frequency of formation increases and hence the time to detachment of a forming bubble decreases, as the superficial liquid velocity is in-creased. Furthermore, it is shown that the void fraction of the resulting two-phase flow increases with volumetric gas flow rate Q(sub d), pipe diameter and gas injection nozzle diameter, while they decrease with surrounding liquid flow. The important role played by flowing liquid in detaching bubbles in a reduced gravity environment is thus emphasized. We observe that the void fraction can be accurately controlled by using single nozzle gas injection, rather than by employing multiple port injection, since the later system gives rise to unpredictable coalescence of adjacent bubbles. It is of interest to note that empirical bubble size and corresponding void fraction are somewhat smaller for the co-flow geometry than the cross-flow configuration at similar flow conditions with similar pipe and nozzle diameters. In order to supplement the empirical data, a theoretical model is employed to study single bubble generation in the dynamic (Q(sub d) = 1 - 1000 cu cm/s) and bubbly flow regime within the framework of the co-flow configuration. This theoretical model is based on an overall force balance acting on the bubble during the two stages of generation, namely the expansion and the detachment stage. Two sets of forces, one aiding and the other inhibiting bubble detachment are identified. Under conditions of reduced gravity, gas momentum flux enhances, while the surface tension force at the air injection nozzle tip inhibits bubble detachment. In parallel, liquid drag and inertia can act as both attaching and detaching forces, depending on the relative velocity of the bubble with respect to the surrounding liquid. Predictions of the theoretical model compare well with our experimental results. However, at higher superficial liquid velocities, as the bubble loses its spherical form, empirical bubble size no longer matches the theoretical predictions. In summary, we have developed a combined experimental and theoretical work, which describes the complex process of bubble generation and resulting two-phase flow in a microgravity environment. Results of the present study can be used in a wide range of space-based applications, such as thermal energy and power generation, propulsion, cryogenic storage and long duration life support systems, necessary for programs such as NASA's Human Exploration for the Development of Space (HEDS).

Generation and characterization of gas bubbles in liquid metals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eckert, S.; Gerbeth, G.; Witke, W.

1996-06-01

There is an ongoing research performed in the RCR on local transport phenomena in turbulent liquid metal (LM) duct flows exposed to external magnetic fields. In this context so-called MHD flow phenomena can be observed, which are unknown in usual hydraulic engineering. The field of interest covers also the influence of magnetic fields on the behaviour of liquid metal - gas mixtures. Profound knowledge on these LMMHD two-phase flow plays an important role in a variety of technological applications, in particular, in the design of Liquid-Metal MHD generators or for several metallurgical processes employing gas-stirred reactors. However, the highly empiricalmore » nature of two-phase flow analysis gives little hope for the prediction of MHD two-phase flows without extensive experimental data. A summary is given about the authors research activities focussing on two directions: (a) Momentum transfer between gas and liquid metal in a bubbly flow regime to investigate the influence of the external magnetic field on the velocity slip ration S (b) Peculiarities of the MHD turbulence to use small gas bubbles as local tracers in order to study the turbulent mass transfer.« less

Suppression of AGN-Driven Turbulence by Magnetic Fields in a Magnetohydrodynamic Model of the Intracluster Medium

NASA Astrophysics Data System (ADS)

Bambic, Christopher J.; Morsony, Brian; Reynolds, Christopher S.

2018-01-01

We investigate the role of AGN feedback in turbulent heating of galaxy clusters. Specifically, we analyze the production of turbulence by g-modes generated by the supersonic expansion and buoyant rise of AGN-driven bubbles. Previous work which neglects magnetic fields has shown that this process is inefficient, with less than 1% of the injected energy ending up in turbulence. This inefficiency is primarily due to the fact that the bubbles are shredded apart by hydrodynamic instabilities before they can excite sufficiently strong g-modes. Using a plane-parallel model of the ICM and 3D ideal MHD simulations, we examine the role of a large-scale magnetic field which is able to drape around these rising bubbles, preserving them from hydrodynamic instabilities. We find that, while magnetic draping appears better able to preserve AGN-driven bubbles, the driving of g-modes and the resulting production of turbulence is still inefficient. The magnetic tension force prevents g-modes from transitioning into the nonlinear regime, suppressing turbulence in our model ICM below levels measured in hydrodynamic simulations. Our work highlights the ways in which ideal MHD is an insufficient description for the cluster feedback process, and we discuss future work such as the inclusion of anisotropic viscosity as a means of simulating high β plasma kinetic effects. These results suggest the hypothesis that other mechanisms of heating the ICM plasma such as sound waves or cosmic rays may be responsible for observed feedback in galaxy clusters.

Inactivation of viruses in bubbling processes utilized for personal bioaerosol monitoring.

PubMed

Agranovski, I E; Safatov, A S; Borodulin, A I; Pyankov, O V; Petrishchenko, V A; Sergeev, A N; Agafonov, A P; Ignatiev, G M; Sergeev, A A; Agranovski, V

2004-12-01

A new personal bioaerosol sampler has recently been developed and evaluated for sampling of viable airborne bacteria and fungi under controlled laboratory conditions and in the field. The operational principle of the device is based on the passage of air through porous medium immersed in liquid. This process leads to the formation of bubbles within the filter as the carrier gas passes through and thus provides effective mechanisms for aerosol removal. As demonstrated in previous studies, the culturability of sampled bacterium and fungi remained high for the entire 8-h sampling period. The present study is the first step of the evaluation of the new sampler for monitoring of viable airborne viruses. It focuses on the investigation of the inactivation rate of viruses in the bubbling process during 4 h of continuous operation. Four microbes were used in this study, influenza, measles, mumps, and vaccinia viruses. It was found that the use of distilled water as the collection fluid was associated with a relatively high decay rate. A significant improvement was achieved by utilizing virus maintenance fluid prepared by using Hank's solution with appropriate additives. The survival rates of the influenza, measles, and mumps viruses were increased by 1.4 log, 0.83 log, and 0.82 log, respectively, after the first hour of operation compared to bubbling through the sterile water. The same trend was observed throughout the entire 4-h experiment. There was no significant difference observed only for the robust vaccinia virus.

Inactivation of Viruses in Bubbling Processes Utilized for Personal Bioaerosol Monitoring

PubMed Central

Agranovski, I. E.; Safatov, A. S.; Borodulin, A. I.; Pyankov, O. V.; Petrishchenko, V. A.; Sergeev, A. N.; Agafonov, A. P.; Ignatiev, G. M.; Sergeev, A. A.; Agranovski, V.

2004-01-01

A new personal bioaerosol sampler has recently been developed and evaluated for sampling of viable airborne bacteria and fungi under controlled laboratory conditions and in the field. The operational principle of the device is based on the passage of air through porous medium immersed in liquid. This process leads to the formation of bubbles within the filter as the carrier gas passes through and thus provides effective mechanisms for aerosol removal. As demonstrated in previous studies, the culturability of sampled bacterium and fungi remained high for the entire 8-h sampling period. The present study is the first step of the evaluation of the new sampler for monitoring of viable airborne viruses. It focuses on the investigation of the inactivation rate of viruses in the bubbling process during 4 h of continuous operation. Four microbes were used in this study, influenza, measles, mumps, and vaccinia viruses. It was found that the use of distilled water as the collection fluid was associated with a relatively high decay rate. A significant improvement was achieved by utilizing virus maintenance fluid prepared by using Hank's solution with appropriate additives. The survival rates of the influenza, measles, and mumps viruses were increased by 1.4 log, 0.83 log, and 0.82 log, respectively, after the first hour of operation compared to bubbling through the sterile water. The same trend was observed throughout the entire 4-h experiment. There was no significant difference observed only for the robust vaccinia virus. PMID:15574888

Microwave vector radiative transfer equation of a sea foam layer by the second-order Rayleigh approximation

NASA Astrophysics Data System (ADS)

Wei, En-Bo

2011-10-01

The microwave vector radiative transfer (VRT) equation of a coated spherical bubble layer is derived by means of the second-order Rayleigh approximation field when the microwave wavelength is larger than the coated spherical particle diameter. Meanwhile, the perturbation method is developed to solve the second-order Rayleigh VRT equation for the small ratio of the volume scattering coefficient to the extinction coefficient. As an example, the emissive properties of a sea surface foam layer, which consists of seawater coated bubbles, are investigated. The extinction, absorption, and scattering coefficients of sea foam are obtained by the second-order Rayleigh approximation fields and discussed for the different microwave frequencies and the ratio of inner radius to outer radius of a coated bubble. Our results show that in the dilute limit, the volume scattering coefficient decreases with increasing the ratio of inner radius to outer radius and decreasing the frequencies. It is also found that the microwave emissivity and the extinction coefficient have a peak at very thin seawater coating and its peak value decreases with frequency decrease. Furthermore, with the VRT equation and effective medium approximation of densely coated bubbles, the mechanism of sea foam enhancing the emissivity of a sea surface is disclosed. In addition, excellent agreement is obtained by comparing our VRT results with the experimental data of microwave emissivities of sea surface covered by a sea foam layer at L-band (1.4 GHz) and the Camps' model.

Ex vivo blood vessel bioreactor for analysis of the biodegradation of magnesium stent models with and without vessel wall integration

PubMed Central

Wang, Juan; Liu, Lumei; Wu, Yifan; Maitz, Manfred F.; Wang, Zhihong; Koo, Youngmi; Zhao, Ansha; Sankar, Jagannathan; Kong, Deling; Huang, Nan; Yun, Yeoheung

2017-01-01

Current in vitro models fail in predicting the degradation rate and mode of magnesium (Mg) stents in vivo. To overcome this, the microenvironment of the stent is simulated here in an ex vivo bioreactor with porcine aorta and circulating medium, and compared with standard static in vitro immersion and with in vivo rat aorta models. In ex vivo and in vivo conditions, pure Mg wires were exposed to the aortic lumen and inserted into the aortic wall to mimic early- and long-term implantation, respectively. Results showed that: 1) Degradation rates of Mg were similar for all the fluid diffusion conditions (in vitro static, aortic wall ex vivo and in vivo); however, Mg degradation under flow condition (i.e. in the lumen) in vivo was slower than ex vivo; 2) The corrosion mode in the samples can be mainly described as localized (in vitro), mixed localized and uniform (ex vivo), and uniform (in vivo); 3) Abundant degradation products (MgO/Mg(OH)2 and Ca/P) with gas bubbles accumulated around the localized degradation regions ex vivo, but a uniform and thin degradation product layer was found in vivo. It is concluded that the ex vivo vascular bioreactor provides an improved test setting for magnesium degradation between static immersion and animal experiments and highlights its promising role in bridging degradation behavior and biological response for vascular stent research. PMID:28013101

Photothermal nanoblade for patterned cell membrane cutting

PubMed Central

Wu, Ting-Hsiang; Teslaa, Tara; Teitell, Michael A.; Chiou, Pei-Yu

2010-01-01

We report a photothermal nanoblade that utilizes a metallic nanostructure to harvest short laser pulse energy and convert it into a highly localized and specifically shaped explosive vapor bubble. Rapid bubble expansion and collapse punctures a lightly-contacting cell membrane via high-speed fluidic flows and induced transient shear stress. The membrane cutting pattern is controlled by the metallic nanostructure configuration, laser pulse polarization, and energy. Highly controllable, sub-micron sized circular hole pairs to half moon-like, or cat-door shaped, membrane cuts were realized in glutaraldehyde treated HeLa cells. PMID:21164656

Quantifying dynamic rheology, phase interactions and strain localisation in deforming three phase magmas using high-speed x-ray tomography

NASA Astrophysics Data System (ADS)

Dobson, Katherine; Pistone, Mattia; Fife, Julie; Cordonnier, Benoit; Blundy, Jon; Dingwell, Don; Lee, Peter

2015-04-01

The crystal and bubble cargoes of magmas are critical to controlling magma mobility and rheology. These cargos vary in both time and space and the local, and bulk, rheological behaviour are correspondingly heterogeneous. Tracking how these heterogeneous cargoes evolve, and how crystals and bubbles interact with each other in deforming systems is a critical challenge in volcanology, as these processes control both the chemical and physical evolution of the magma, including phenomena such as melt-crystal segregation, strain localisation, and fragmentation. The only methodology available to track these processes in real time, and at the scale of individual melt-crystal-bubble interactions is high speed x-ray tomography. This non-destructive imaging technique allows the rapid acquisition of sequential 3D images that capture the physical, and to some degree chemical, microstructure of the sample during a deformation cycle. We utilise in situ tomographic methods developed in materials science to perfume magmatic deformation experiments on synthesized three phase systems at magmatic temperatures. Through a novel combination of a high temperature laser heating system [1] in situ micro-precision deformation apparatus [2] and the temporal and spatial resolution available at the TOMCAT beam line at the Swiss Light Source synchrotron facility we performed in situ observations of the microstructural evolution of a synthesized anhydrous borosilicate melt seeded with a variable concentration of non-reactive rutile crystals and air bubbles (30-70 volume %). The experiments were conducted at 800-1000C, under constant deformation rates of 0.25-5.00 microns/second. Each 3D image has 2D and 3D spatial resolution of approximately 3 microns per pixel, and each 3D image took ~3 seconds to acquire. Here we present this innovative high speed, high temperature, syn-deformation tomographic data , and show how it can be used to trace the location and local distribution of each crystal and bubble within a small volume cylindrical experimental charge (3mm diameter, 5mm length) undergoing shear along a single vertical plane. By qualitative and quantitative analysis of the sequential images collected over 5-15 minute deformation cycles we track the local bubble, crystal and melt concentrations on a range of spatial scales. From this we calculate a spatially heterogeneous and dynamic local viscosity [3] and assess our results against recently developed 3-phase rheological models [4]. We will present how this real time 4D information can be used to quantify the dynamics of magma motion, discuss the implications of spatially and temporally variable rheological behaviours, and show how this novel technique can be integrated with other volcanology methods to improve our understanding of volcanic and magmatic processes. [1] Fife et al. 2012. J. Synchrotron Rad. 19, 352-358 [2] Kareh et al. 2014 Nature Comm. 5 4464. [3] Giordano, et al. 2008 EPSL 271 123-134. [4] Truby et al. 2015 P.Roy.Soc.A. 2015471 20140557

What are the limits of energy focusing in sonoluminescence?

NASA Astrophysics Data System (ADS)

Putterman, Seth; Camara, C.; Kappus, B.; Su, C. K.; Kirilov, E.

2003-04-01

Sonoluminescence [SL] is amazing for the extraordinary degree by which ultrasonic energy can be focused by a cavitating bubble. Local energy dissipation exceeds Kirkhoff's law by 1E15 and the acoustic energy density concentrates by 12 orders of magnitude to create picosecond flashes of broadband ultraviolet light. At the minimum bubble radius, the acceleration exceeds 1E11 g and a megabar level shock wave is emitted into the surrounding fluid. For single bubbles driven at 30 KHz, SL is nature's smallest blackbody. This implies that the bubble's interior is such a dense plasma that the photon-matter mean free path is shorter than the wavelength of light, and suggests that SL originates in an unusual state of matter. Excitation of a vertical column of fluid [~10 Hz] so as to create a water hammer leads to the upscaling of SL and generation of flashes of light with 3E8 photons and peak powers approaching 1 W. At 1 MHz, the spectrum resembles bremsstrahlung from a transparent plasma with a temperature ~1 MK. At 10 MHz the collapsed size of the SL bubble approaches 10 nm, which raises the possibility that the SL parameter space may extend to the domain of quantum mechanics. [Research supported by DARPA and DOE.

Helium-filled soap bubbles tracing fidelity in wall-bounded turbulence

NASA Astrophysics Data System (ADS)

Faleiros, David Engler; Tuinstra, Marthijn; Sciacchitano, Andrea; Scarano, Fulvio

2018-03-01

The use of helium-filled soap bubbles (HFSB) as flow tracers for particle image velocimetry (PIV) and particle tracking velocimetry (PTV) to measure the properties of turbulent boundary layers is investigated in the velocity range from 30 to 50 m/s. The experiments correspond to momentum thickness-based Reynolds numbers of 3300 and 5100. A single bubble generator delivers nearly neutrally buoyant HFSB to seed the air flow developing over the flat plate. The HFSB motion analysis is performed by PTV using single-frame multi-exposure recordings. The measurements yield the local velocity and turbulence statistics. Planar two-component-PIV measurements with micron-sized droplets (DEHS) conducted under the same conditions provide reference data for the quantities of interest. In addition, the behavior of air-filled soap bubbles is studied where the effect of non-neutral buoyancy is more pronounced. The mean velocity profiles as well as the turbulent stresses obtained with HFSB are in good agreement with the flow statistics obtained with DEHS particles. The study illustrates that HFSB tracers can be used to determine the mean velocity and the turbulent fluctuations of turbulent boundary layers above a distance of approximately two bubble diameters from the wall. This work broadens the current range of application of HFSB from external aerodynamics of large-scale-PIV experiments towards wall-bounded turbulence.

Steady boiling of vapor bubbles in rectangular channels

NASA Astrophysics Data System (ADS)

Ajaev, Vladimir S.; Homsy, George M.

2000-11-01

We consider vapor bubbles in microchannels in which the vapor is produced by a heater element and condenses in cooler parts of the interface. The free boundary problem is formulated for a long steady-state bubble in a rectangular channel with a heated bottom. The shape of the liquid-vapor interface is described using lubrication-type equations in the regime in which the vapor phase fills most of the cross-section. Contact lines may be present, marking the transitions between molecularly thin films and macroscopic ones. The main parameters are the differences between heater, saturation, and top wall temperatures. The equations are solved numerically over a range of parameter values with an integral condition requiring the evaporation near the heater to balance condensation in colder areas of the interface. Depending on the temperature, the side walls can be either dry or covered with a liquid film; we identify criteria for these two different regimes. The asymptotic method breaks down in the limit when capillary condensation becomes important near the bubble top and a different approach is used to determine the shape of the bubble in this limit. Solutions here involve localized regions of large mass fluxes, which are asymptotically matched to capillary-statics regions where the heat transfer is negligible.

Internal gas and liquid distributor for electrodeionization device

DOEpatents

Lin, YuPo J.; Snyder, Seth W.; Henry, Michael P.; Datta, Saurav

2016-05-17

The present invention provides a resin-wafer electrodeionization (RW-EDI) apparatus including cathode and anode electrodes separated by a plurality of porous solid ion exchange resin wafers, which when in use are filled with an aqueous fluid. The apparatus includes one or more wafers comprising a basic ion exchange medium, and preferably includes one or more wafers comprising an acidic ion exchange medium. The wafers are separated from one another by ion exchange membranes. The gas and aqueous fluid are introduced into each basic wafer via a porous gas distributor which disperses the gas as micro-sized bubbles laterally throughout the distributor before entering the wafer. The fluid within the acidic and/or basic ion exchange wafers preferably includes, or is in contact with, a carbonic anhydrase (CA) enzyme or inorganic catalyst to facilitate conversion of bicarbonate ion to carbon dioxide within the acidic medium.

Plasma generated in culture medium induces damages of HeLa cells due to flow phenomena

NASA Astrophysics Data System (ADS)

Sato, Yusuke; Sato, Takehiko; Yoshino, Daisuke

2018-03-01

Plasma in a liquid has been anticipated as an effective tool for medical applications, however, few reports have described cellular responses to plasma generated in a liquid similar to biological fluids. Herein we report the effects of plasma generated in a culture medium on HeLa cells. The plasma in the culture medium produced not only heat, shock waves, and reactive chemical species but also a jet flow with sub millimeter-sized bubbles. Cells exposed to the plasma exhibited detachment, morphological changes, and changes in the actin cytoskeletal structure. The experimental results suggest that wall shear stress over 160 Pa was generated on the surface of the cells by the plasma. It is one of the main factors that cause those cellular responses. We believe that our findings would provide valuable insight into advancements in medical applications of plasma in a liquid.

The Plasma Environment Associated With Equatorial Ionospheric Irregularities

NASA Astrophysics Data System (ADS)

Smith, Jonathon M.; Heelis, R. A.

2018-02-01

We examine the density structure of equatorial depletions referred to here as equatorial plasma bubbles (EPBs). Data recorded by the Ion Velocity Meter as part of the Coupled Ion Neutral Dynamics Investigation (CINDI) aboard the Communication/Navigation Outage Forecasting System (C/NOFS) satellite are used to study EPBs from 1600 to 0600 h local time at altitudes from 350 to 850 km. The data are taken during the 7 years from 2008 to 2014, more than one half of a magnetic solar cycle, that include solar minimum and a moderate solar maximum. Using a rolling ball algorithm, EPBs are identified by profiles in the plasma density, each having a depth measured as the percent change between the background and minimum density (ΔN/N). During solar moderate activity bubbles observed in the topside postsunset sector are more likely to have large depths compared to those observed in the topside postmidnight sector. Large bubble depths can be observed near 350 km in the bottomside F region in the postsunset period. Conversely at solar minimum the distribution of depths is similar in the postsunset and postmidnight sectors in all longitude sectors. Deep bubbles are rarely observed in the topside postsunset sector and never in the bottomside above 400 km in altitude. We suggest that these features result from the vertical drift of the plasma for these two solar activity levels. These drift conditions affect both the background density in which bubbles are embedded and the growth rate of perturbations in the bottomside where bubbles originate.

Numerical and Experimental Study of Mechanisms Involved in Boiling Histotripsy.

PubMed

Pahk, Ki Joo; Gélat, Pierre; Sinden, David; Dhar, Dipok Kumar; Saffari, Nader

2017-12-01

The aim of boiling histotripsy is to mechanically fractionate tissue as an alternative to thermal ablation for therapeutic applications. In general, the shape of a lesion produced by boiling histotripsy is tadpole like, consisting of a head and a tail. Although many studies have demonstrated the efficacy of boiling histotripsy for fractionating solid tumors, the exact mechanisms underpinning this phenomenon are not yet well understood, particularly the interaction of a boiling vapor bubble with incoming incident shockwaves. To investigate the mechanisms involved in boiling histotripsy, a high-speed camera with a passive cavitation detection system was used to observe the dynamics of bubbles produced in optically transparent tissue-mimicking gel phantoms exposed to the field of a 2.0-MHz high-intensity focused ultrasound (HIFU) transducer. We observed that boiling bubbles were generated in a localized heated region and cavitation clouds were subsequently induced ahead of the expanding bubble. This process was repeated with HIFU pulses and eventually resulted in a tadpole-shaped lesion. A simplified numerical model describing the scattering of the incident ultrasound wave by a vapor bubble was developed to help interpret the experimental observations. Together with the numerical results, these observations suggest that the overall size of a lesion induced by boiling histotripsy is dependent on the sizes of (i) the heated region at the HIFU focus and (ii) the backscattered acoustic field by the original vapor bubble. Copyright © 2017 World Federation for Ultrasound in Medicine and Biology. Published by Elsevier Inc. All rights reserved.

Generation of a nonequlibrium plasma in heterophase atmospheric-pressure gas-liquid media and demonstration of its sterilization ability

DOE Office of Scientific and Technical Information (OSTI.GOV)

Akishev, Yu. S.; Grushin, M. E.; Karal'nik, V. B.

Results are presented from experiments on the generation of a low-temperature nonequilibrium plasma in atmospheric-pressure heterophase gas-liquid media of different compositions: (i) a liquid with air bubbles and (ii) air with liquid aerosol. To illustrate possible application of a low-temperature plasma in a heterophase medium, experiments on the inactivation of some microorganisms by a low-temperature plasma have been performed.

Coalescence preference in densely packed microbubbles

DOE PAGES

Kim, Yeseul; Lim, Su Jin; Gim, Bopil; ...

2015-01-13

A bubble merged from two parent bubbles with different size tends to be placed closer to the larger parent. This phenomenon is known as the coalescence preference. Here we demonstrate that the coalescence preference can be blocked inside a densely packed cluster of bubbles. We utilized high-speed high-resolution X-ray microscopy to clearly visualize individual coalescence events inside densely packed microbubbles with a local packing fraction of ~40%. Thus, the surface energy release theory predicts an exponent of 5 in a relation between the relative coalescence position and the parent size ratio, whereas our observation for coalescence in densely packed microbubblesmore » shows a different exponent of 2. We believe that this result would be important to understand the reality of coalescence dynamics in a variety of packing situations of soft matter.« less

Drug delivery with microsecond laser pulses into gelatin.

PubMed

Shangguan, H; Casperson, L W; Shearin, A; Gregory, K W; Prahl, S A

1996-07-01

Photo acoustic drug delivery is a technique for localized drug delivery by laser-induced hydrodynamic pressure following cavitation bubble expansion and collapse. Photoacoustic drug delivery was investigated on gelatin-based thrombus models with planar and cylindrical geometries by use of one microsecond laser pulses. Solutions of a hydrophobic dye in mineral oil permitted monitoring of delivered colored oil into clear gelatin-based thrombus models. Cavitation bubble development and photoacoustic drug delivery were visualized with flash photography. This study demonstrated that cavitation is the governing mechanism for photoacoustic drug delivery, and the deepest penetration of colored oil in gels followed the bubble collapse. Spatial distribution measurements revealed that colored oil could be driven a few millimeters into the gels in both axial and radial directions, and the penetration was less than 500 µm when the gelatin structure was not fractured.

Coalescence preference in densely packed microbubbles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Yeseul; Lim, Su Jin; Gim, Bopil

A bubble merged from two parent bubbles with different size tends to be placed closer to the larger parent. This phenomenon is known as the coalescence preference. Here we demonstrate that the coalescence preference can be blocked inside a densely packed cluster of bubbles. We utilized high-speed high-resolution X-ray microscopy to clearly visualize individual coalescence events inside densely packed microbubbles with a local packing fraction of ~40%. Thus, the surface energy release theory predicts an exponent of 5 in a relation between the relative coalescence position and the parent size ratio, whereas our observation for coalescence in densely packed microbubblesmore » shows a different exponent of 2. We believe that this result would be important to understand the reality of coalescence dynamics in a variety of packing situations of soft matter.« less

Hydrodynamic models for slurry bubble column reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gidaspow, D.

1995-12-31

The objective of this investigation is to convert a {open_quotes}learning gas-solid-liquid{close_quotes} fluidization model into a predictive design model. This model is capable of predicting local gas, liquid and solids hold-ups and the basic flow regimes: the uniform bubbling, the industrially practical churn-turbulent (bubble coalescence) and the slugging regimes. Current reactor models incorrectly assume that the gas and the particle hold-ups (volume fractions) are uniform in the reactor. They must be given in terms of empirical correlations determined under conditions that radically differ from reactor operation. In the proposed hydrodynamic approach these hold-ups are computed from separate phase momentum balances. Furthermore,more » the kinetic theory approach computes the high slurry viscosities from collisions of the catalyst particles. Thus particle rheology is not an input into the model.« less

Buoyancy, Uplift, and AGN Feedback - Deep Chandra and XMM-Newton Observations of the Radio Outbursts in NGC 4472 and NGC 1399

NASA Astrophysics Data System (ADS)

Kraft, R.; Su, Y.; Gendron Marsolais, M.; Roediger, E.; Nulsen, P.; Hlavacek-Larrondo, J.; Forman, W.; Jones, C.; Randall, S.; Machacek, M.

2017-10-01

We present results from deep Chandra and XMM-Newton observations of the AGN outbursts in the nearby early-type galaxies NGC 4472 and NGC 1399. Both pairs of radio bubbles are surrounded by rims of enhanced X-ray emission. Spectral analysis shows that the temperatures of these rims are less than that of the surrounding medium, suggesting that they are gas uplifted from the group center by the buoyant rise of the radio bubbles and not shocks due to the supersonic inflation of the lobes. The energy required to uplift these shells can be a significant fraction of the total outburst energy, and thus may play an important role in the thermodynamic evolution of the galaxy core. Buoyant uplift could also be a very efficient means of transporting metals from the galaxy core to the halo.

Immobilization of Trametes versicolor cultures for improving laccase production in bubble column reactor intensified by sonication.

PubMed

Wang, Feng; Guo, Chen; Liu, Chun-Zhao

2013-01-01

The mycelia of Trametes versicolor immobilized in alginate beads provided higher laccase production than that in pelleted form. An efficient ultrasonic treatment enhanced laccase production from the immobilized T. versicolor cultures. The optimized treatment process consisted of exposing 36-h-old bead cultures to 7-min ultrasonic treatments twice with a 12-h interval using a fixed ultrasonic power and frequency (120 W, 40 kHz). Using the intensification strategy with sonication, laccase production increased by more than 2.1-fold greater than the untreated control in both flasks and bubble column reactors. The enhancement of laccase production by ultrasonic treatment is related to the improved mass transfer of nutrients and product between the liquid medium and the gel matrix. These results provide a basis for the large-scale and highly-efficient production of laccase using sonobioreactors.

A computational efficient modelling of laminar separation bubbles

NASA Technical Reports Server (NTRS)

Dini, Paolo; Maughmer, Mark D.

1990-01-01

In predicting the aerodynamic characteristics of airfoils operating at low Reynolds numbers, it is often important to account for the effects of laminar (transitional) separation bubbles. Previous approaches to the modelling of this viscous phenomenon range from fast but sometimes unreliable empirical correlations for the length of the bubble and the associated increase in momentum thickness, to more accurate but significantly slower displacement-thickness iteration methods employing inverse boundary-layer formulations in the separated regions. Since the penalty in computational time associated with the more general methods is unacceptable for airfoil design applications, use of an accurate yet computationally efficient model is highly desirable. To this end, a semi-empirical bubble model was developed and incorporated into the Eppler and Somers airfoil design and analysis program. The generality and the efficiency was achieved by successfully approximating the local viscous/inviscid interaction, the transition location, and the turbulent reattachment process within the framework of an integral boundary-layer method. Comparisons of the predicted aerodynamic characteristics with experimental measurements for several airfoils show excellent and consistent agreement for Reynolds numbers from 2,000,000 down to 100,000.

Mercury Cavitation Phenomenon in Pulsed Spallation Neutron Sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Futakawa, Masatoshi; Naoe, Takashi; Kawai, Masayoshi

2008-06-24

Innovative researches will be performed at Materials and Life Science Experimental Facility in J-PARC, in which a mercury target system will be installed as MW-class pulse spallation neutron sources. Proton beams will be injected into mercury target to induce the spallation reaction. At the moment the intense proton beam hits the target, pressure waves are generated in the mercury because of the abrupt heat deposition. The pressure waves interact with the target vessel leading to negative pressure that may cause cavitation along the vessel wall. Localized impacts by micro-jets and/or shock waves which are caused by cavitation bubble collapse imposemore » pitting damage on the vessel wall. The pitting damage which degrades the structural integrity of target vessels is a crucial issue for high power mercury targets. Micro-gas-bubbles injection into mercury may be useful to mitigate the pressure wave and the pitting damage. The visualization of cavitation-bubble and gas-bubble collapse behaviors was carried out by using a high-speed video camera. The differences between them are recognized.« less

Quasiopen inflation

NASA Astrophysics Data System (ADS)

García-Bellido, Juan; Garriga, Jaume; Montes, Xavier

1998-04-01

We show that a large class of two-field models of single-bubble open inflation does not lead to infinite open universes, as was previously thought, but to an ensemble of very large but finite inflating ``islands.'' The reason is that the quantum tunneling responsible for the nucleation of the bubble does not occur simultaneously along both field directions and equal-time hypersurfaces in the open universe are not synchronized with equal-density or fixed-field hypersurfaces. The most probable tunneling trajectory corresponds to a zero value of the inflaton field; large values, necessary for the second period of inflation inside the bubble, only arise as localized fluctuations. The interior of each nucleated bubble will contain an infinite number of such inflating regions of comoving size of order γ-1, where γ is the supercurvature eigenvalue, which depends on the parameters of the model. Each one of these islands will be a quasi-open universe. Since the volume of the hyperboloid is infinite, inflating islands with all possible values of the field at their center will be realized inside of a single bubble. We may happen to live in one of those patches of comoving size d<~γ-1, where the universe appears to be open. In particular, we consider the ``supernatural'' model proposed by Linde and Mezhlumian. There, an approximate U(1) symmetry is broken by a tunneling field in a first order phase transition, and slow-roll inflation inside the nucleated bubble is driven by the pseudo Goldstone field. We find that the excitations of the pseudo Goldstone field produced by the nucleation and subsequent expansion of the bubble place severe constraints on this model. We also discuss the coupled and uncoupled two-field models.

Modeling ultrafast laser-induced nanocavitation around plasmonic nanoparticles (Conference Presentation)

NASA Astrophysics Data System (ADS)

Meunier, Michel; Dagallier, Adrien; Lachaine, Rémi; Boutopoulos, Christos; Boulais, Étienne

2017-03-01

Vapor nanobubbles generated around plasmonic nanoparticles (NPs) by ultrafast laser irradiation are efficient for inducing localized damage to living cells. Killing targeted cancer cells or gene delivery can therefore be envisioned using this new technology [1,2]. The extent of the damage and its non-lethal character are linked to the size of the nanobubble. Precise understanding of the mechanisms leading to bubble formation around plasmonic nanostructures is necessary to optimize the technique. In this presentation, we present a complete model that successfully describes all interactions occurring during the irradiation of plasmonics nanostructures by an ultrafast laser of various pulse widths and fluences. Nanoavitation is caused by the interplay between heat conduction at the NP-medium interface and non-linear plasmon-enhanced photoionization of a nanoplasma in the near-field [3-5], the former being dominant for in-resonance and the latter for off-resonance irradiation. Modeling of the whole laser-nanoparticle interaction, together with the help of the shadowgraphic imaging and scattering techniques [3-5], give valuable insight on the mechanisms of cavitation at the nanoscale, leading to possible optimization of the nanostructure for bubble-based nanomedicine applications. 1- E. Boulais, R. Lachaine, A. Hatef, and M. Meunier, Journal of Photochemistry and Photobiology C: Photochemistry Reviews 17, 26-49 (2013). 2- E. Bergeron, S. Patskovsky, D. Rioux, and M. Meunier, Nanoscale 7,17836-17847 (2015). 3- E. Boulais, R. Lachaine, and M. Meunier, Nano Letters 12, 4763-4769 (2012). 4- R. Lachaine, E. Boulais, and M. Meunier, ACS Photonics 1, 331-336 (2014). 5- C. Boutopoulos, A. Hatef, M. Fortin-Deschênes, and M. Meunier Nanoscale 7,11758-11765 (2015).

Effects of free-stream turbulence intensity on transition in a laminar separation bubble formed over an airfoil

NASA Astrophysics Data System (ADS)

Istvan, Mark S.; Yarusevych, Serhiy

2018-03-01

The laminar-to-turbulent transition process in a laminar separation bubble formed over a NACA 0018 airfoil is investigated experimentally. All experiments are performed for an angle of attack of 4°, chord Reynolds numbers of 80,000 and 125,000, and free-stream turbulence intensities between 0.06 and 1.99%. The results show that increasing the level of free-stream turbulence intensity leads to a decrease in separation bubble length, attributed to a downstream shift in mean separation and an upstream shift in mean reattachment, the later ascribed to an upstream shift in mean transition. Maximum spatial amplification rates of disturbances in the separated shear layer decrease with increasing free-stream turbulence intensity, implying that the larger initial amplitudes of disturbances are solely responsible for the upstream shift in mean transition and as a result mean reattachment. At the baseline level of turbulence intensity, coherent structures forming in the aft portion of the bubble are characterized by strong spanwise coherence at formation, and undergo spanwise deformations leading to localized breakup in the vicinity of mean reattachment. As the level of free-stream turbulence intensity is increased, the spanwise coherence of the shear layer rollers is reduced, and spanwise undulations in the vortex filaments start to take place at the mean location of roll-up. At the highest level of turbulence intensity investigated, streamwise streaks originating in the boundary layer upstream of the separation bubble are observed within the bubble. These streaks signify an onset of bypass transition upstream of the separation bubble, which gives rise to a highly three-dimensional shear layer roll-up. A quantitative analysis of the associated changes in salient characteristics of the coherent structures is presented, connecting the effect of elevated free-stream turbulence intensity on the time-averaged and dynamic characteristics of the separation bubble.

The quiescent intracluster medium in the core of the Perseus cluster.

PubMed

2016-07-07

Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes of cosmological parameters and many astrophysical processes. However, knowledge of the dynamics of the pervasive hot gas, the mass of which is much larger than the combined mass of all the stars in the cluster, is lacking. Such knowledge would enable insights into the injection of mechanical energy by the central supermassive black hole and the use of hydrostatic equilibrium for determining cluster masses. X-rays from the core of the Perseus cluster are emitted by the 50-million-kelvin diffuse hot plasma filling its gravitational potential well. The active galactic nucleus of the central galaxy NGC 1275 is pumping jetted energy into the surrounding intracluster medium, creating buoyant bubbles filled with relativistic plasma. These bubbles probably induce motions in the intracluster medium and heat the inner gas, preventing runaway radiative cooling--a process known as active galactic nucleus feedback. Here we report X-ray observations of the core of the Perseus cluster, which reveal a remarkably quiescent atmosphere in which the gas has a line-of-sight velocity dispersion of 164 ± 10 kilometres per second in the region 30-60 kiloparsecs from the central nucleus. A gradient in the line-of-sight velocity of 150 ± 70 kilometres per second is found across the 60-kiloparsec image of the cluster core. Turbulent pressure support in the gas is four per cent of the thermodynamic pressure, with large-scale shear at most doubling this estimate. We infer that a total cluster mass determined from hydrostatic equilibrium in a central region would require little correction for turbulent pressure.

The quiescent intracluster medium in the core of the Perseus cluster

DOE PAGES

Aharonian, Felix; Akamatsu, Hiroki; Akimoto, Fumie; ...

2016-07-06

Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes of cosmological parameters and many astrophysical processes. However, knowledge of the dynamics of the pervasive hot gas, the mass of which is much larger than the combined mass of all the stars in the cluster, is lacking. Such knowledge would enable insights into the injection of mechanical energy by the central supermassive black hole and the use of hydrostatic equilibrium for determining cluster masses. X-rays from the core of the Perseus cluster are emitted by the 50-million-kelvin diffusemore » hot plasma filling its gravitational potential well. The active galactic nucleus of the central galaxy NGC 1275 is pumping jetted energy into the surrounding intracluster medium, creating buoyant bubbles filled with relativistic plasma. These bubbles probably induce motions in the intracluster medium and heat the inner gas, preventing runaway radiative cooling—a process known as active galactic nucleus feedback. In this paper, we report X-ray observations of the core of the Perseus cluster, which reveal a remarkably quiescent atmosphere in which the gas has a line-of-sight velocity dispersion of 164 ± 10 kilometres per second in the region 30–60 kiloparsecs from the central nucleus. A gradient in the line-of-sight velocity of 150 ± 70 kilometres per second is found across the 60-kiloparsec image of the cluster core. Turbulent pressure support in the gas is four per cent of the thermodynamic pressure, with large-scale shear at most doubling this estimate. Finally, we infer that a total cluster mass determined from hydrostatic equilibrium in a central region would require little correction for turbulent pressure.« less

The quiescent intracluster medium in the core of the Perseus cluster

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aharonian, Felix; Akamatsu, Hiroki; Akimoto, Fumie

Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes of cosmological parameters and many astrophysical processes. However, knowledge of the dynamics of the pervasive hot gas, the mass of which is much larger than the combined mass of all the stars in the cluster, is lacking. Such knowledge would enable insights into the injection of mechanical energy by the central supermassive black hole and the use of hydrostatic equilibrium for determining cluster masses. X-rays from the core of the Perseus cluster are emitted by the 50-million-kelvin diffusemore » hot plasma filling its gravitational potential well. The active galactic nucleus of the central galaxy NGC 1275 is pumping jetted energy into the surrounding intracluster medium, creating buoyant bubbles filled with relativistic plasma. These bubbles probably induce motions in the intracluster medium and heat the inner gas, preventing runaway radiative cooling—a process known as active galactic nucleus feedback. In this paper, we report X-ray observations of the core of the Perseus cluster, which reveal a remarkably quiescent atmosphere in which the gas has a line-of-sight velocity dispersion of 164 ± 10 kilometres per second in the region 30–60 kiloparsecs from the central nucleus. A gradient in the line-of-sight velocity of 150 ± 70 kilometres per second is found across the 60-kiloparsec image of the cluster core. Turbulent pressure support in the gas is four per cent of the thermodynamic pressure, with large-scale shear at most doubling this estimate. Finally, we infer that a total cluster mass determined from hydrostatic equilibrium in a central region would require little correction for turbulent pressure.« less

The quiescent intracluster medium in the core of the Perseus cluster

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aharonian, Felix; Akamatsu, Hiroki; Akimoto, Fumie

2016-07-06

Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes1 of cosmological parameters and many astrophysical processes. However, knowledge of the dynamics of the pervasive hot gas, the mass of which is much larger than the combined mass of all the stars in the cluster, is lacking. Such knowledge would enable insights into the injection of mechanical energy by the central supermassive black hole and the use of hydrostatic equilibrium for determining cluster masses. X-rays from the core of the Perseus cluster are emitted by the 50-million-kelvin diffusemore » hot plasma filling its gravitational potential well. The active galactic nucleus of the central galaxy NGC 1275 is pumping jetted energy into the surrounding intracluster medium, creating buoyant bubbles filled with relativistic plasma. These bubbles probably induce motions in the intracluster medium and heat the inner gas, preventing runaway radiative cooling—a process known as active galactic nucleus feedback2, 3, 4, 5, 6. Here we report X-ray observations of the core of the Perseus cluster, which reveal a remarkably quiescent atmosphere in which the gas has a line-of-sight velocity dispersion of 164 ± 10 kilometres per second in the region 30–60 kiloparsecs from the central nucleus. A gradient in the line-of-sight velocity of 150 ± 70 kilometres per second is found across the 60-kiloparsec image of the cluster core. Turbulent pressure support in the gas is four per cent of the thermodynamic pressure, with large-scale shear at most doubling this estimate. We infer that a total cluster mass determined from hydrostatic equilibrium in a central region would require little correction for turbulent pressure.« less

The quiescent intracluster medium in the core of the Perseus cluster

NASA Astrophysics Data System (ADS)

Hitomi Collaboration; Aharonian, Felix; Akamatsu, Hiroki; Akimoto, Fumie; Allen, Steven W.; Anabuki, Naohisa; Angelini, Lorella; Arnaud, Keith; Audard, Marc; Awaki, Hisamitsu; Axelsson, Magnus; Bamba, Aya; Bautz, Marshall; Blandford, Roger; Brenneman, Laura; Brown, Gregory V.; Bulbul, Esra; Cackett, Edward; Chernyakova, Maria; Chiao, Meng; Coppi, Paolo; Costantini, Elisa; de Plaa, Jelle; den Herder, Jan-Willem; Done, Chris; Dotani, Tadayasu; Ebisawa, Ken; Eckart, Megan; Enoto, Teruaki; Ezoe, Yuichiro; Fabian, Andrew C.; Ferrigno, Carlo; Foster, Adam; Fujimoto, Ryuichi; Fukazawa, Yasushi; Furuzawa, Akihiro; Galeazzi, Massimiliano; Gallo, Luigi; Gandhi, Poshak; Giustini, Margherita; Goldwurm, Andrea; Gu, Liyi; Guainazzi, Matteo; Haba, Yoshito; Hagino, Kouichi; Hamaguchi, Kenji; Harrus, Ilana; Hatsukade, Isamu; Hayashi, Katsuhiro; Hayashi, Takayuki; Hayashida, Kiyoshi; Hiraga, Junko; Hornschemeier, Ann; Hoshino, Akio; Hughes, John; Iizuka, Ryo; Inoue, Hajime; Inoue, Yoshiyuki; Ishibashi, Kazunori; Ishida, Manabu; Ishikawa, Kumi; Ishisaki, Yoshitaka; Itoh, Masayuki; Iyomoto, Naoko; Kaastra, Jelle; Kallman, Timothy; Kamae, Tuneyoshi; Kara, Erin; Kataoka, Jun; Katsuda, Satoru; Katsuta, Junichiro; Kawaharada, Madoka; Kawai, Nobuyuki; Kelley, Richard; Khangulyan, Dmitry; Kilbourne, Caroline; King, Ashley; Kitaguchi, Takao; Kitamoto, Shunji; Kitayama, Tetsu; Kohmura, Takayoshi; Kokubun, Motohide; Koyama, Shu; Koyama, Katsuji; Kretschmar, Peter; Krimm, Hans; Kubota, Aya; Kunieda, Hideyo; Laurent, Philippe; Lebrun, François; Lee, Shiu-Hang; Leutenegger, Maurice; Limousin, Olivier; Loewenstein, Michael; Long, Knox S.; Lumb, David; Madejski, Grzegorz; Maeda, Yoshitomo; Maier, Daniel; Makishima, Kazuo; Markevitch, Maxim; Matsumoto, Hironori; Matsushita, Kyoko; McCammon, Dan; McNamara, Brian; Mehdipour, Missagh; Miller, Eric; Miller, Jon; Mineshige, Shin; Mitsuda, Kazuhisa; Mitsuishi, Ikuyuki; Miyazawa, Takuya; Mizuno, Tsunefumi; Mori, Hideyuki; Mori, Koji; Moseley, Harvey; Mukai, Koji; Murakami, Hiroshi; Murakami, Toshio; Mushotzky, Richard; Nagino, Ryo; Nakagawa, Takao; Nakajima, Hiroshi; Nakamori, Takeshi; Nakano, Toshio; Nakashima, Shinya; Nakazawa, Kazuhiro; Nobukawa, Masayoshi; Noda, Hirofumi; Nomachi, Masaharu; O'Dell, Steve; Odaka, Hirokazu; Ohashi, Takaya; Ohno, Masanori; Okajima, Takashi; Ota, Naomi; Ozaki, Masanobu; Paerels, Frits; Paltani, Stephane; Parmar, Arvind; Petre, Robert; Pinto, Ciro; Pohl, Martin; Porter, F. Scott; Pottschmidt, Katja; Ramsey, Brian; Reynolds, Christopher; Russell, Helen; Safi-Harb, Samar; Saito, Shinya; Sakai, Kazuhiro; Sameshima, Hiroaki; Sato, Goro; Sato, Kosuke; Sato, Rie; Sawada, Makoto; Schartel, Norbert; Serlemitsos, Peter; Seta, Hiromi; Shidatsu, Megumi; Simionescu, Aurora; Smith, Randall; Soong, Yang; Stawarz, Lukasz; Sugawara, Yasuharu; Sugita, Satoshi; Szymkowiak, Andrew; Tajima, Hiroyasu; Takahashi, Hiromitsu; Takahashi, Tadayuki; Takeda, Shin'Ichiro; Takei, Yoh; Tamagawa, Toru; Tamura, Keisuke; Tamura, Takayuki; Tanaka, Takaaki; Tanaka, Yasuo; Tanaka, Yasuyuki; Tashiro, Makoto; Tawara, Yuzuru; Terada, Yukikatsu; Terashima, Yuichi; Tombesi, Francesco; Tomida, Hiroshi; Tsuboi, Yohko; Tsujimoto, Masahiro; Tsunemi, Hiroshi; Tsuru, Takeshi; Uchida, Hiroyuki; Uchiyama, Hideki; Uchiyama, Yasunobu; Ueda, Shutaro; Ueda, Yoshihiro; Ueno, Shiro; Uno, Shin'Ichiro; Urry, Meg; Ursino, Eugenio; de Vries, Cor; Watanabe, Shin; Werner, Norbert; Wik, Daniel; Wilkins, Dan; Williams, Brian; Yamada, Shinya; Yamaguchi, Hiroya; Yamaoka, Kazutaka; Yamasaki, Noriko Y.; Yamauchi, Makoto; Yamauchi, Shigeo; Yaqoob, Tahir; Yatsu, Yoichi; Yonetoku, Daisuke; Yoshida, Atsumasa; Yuasa, Takayuki; Zhuravleva, Irina; Zoghbi, Abderahmen

2016-07-01

Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes of cosmological parameters and many astrophysical processes. However, knowledge of the dynamics of the pervasive hot gas, the mass of which is much larger than the combined mass of all the stars in the cluster, is lacking. Such knowledge would enable insights into the injection of mechanical energy by the central supermassive black hole and the use of hydrostatic equilibrium for determining cluster masses. X-rays from the core of the Perseus cluster are emitted by the 50-million-kelvin diffuse hot plasma filling its gravitational potential well. The active galactic nucleus of the central galaxy NGC 1275 is pumping jetted energy into the surrounding intracluster medium, creating buoyant bubbles filled with relativistic plasma. These bubbles probably induce motions in the intracluster medium and heat the inner gas, preventing runaway radiative cooling—a process known as active galactic nucleus feedback. Here we report X-ray observations of the core of the Perseus cluster, which reveal a remarkably quiescent atmosphere in which the gas has a line-of-sight velocity dispersion of 164 ± 10 kilometres per second in the region 30-60 kiloparsecs from the central nucleus. A gradient in the line-of-sight velocity of 150 ± 70 kilometres per second is found across the 60-kiloparsec image of the cluster core. Turbulent pressure support in the gas is four per cent of the thermodynamic pressure, with large-scale shear at most doubling this estimate. We infer that a total cluster mass determined from hydrostatic equilibrium in a central region would require little correction for turbulent pressure.

A functional renormalization method for wave propagation in random media

NASA Astrophysics Data System (ADS)

Lamagna, Federico; Calzetta, Esteban

2017-08-01

We develop the exact renormalization group approach as a way to evaluate the effective speed of the propagation of a scalar wave in a medium with random inhomogeneities. We use the Martin-Siggia-Rose formalism to translate the problem into a non equilibrium field theory one, and then consider a sequence of models with a progressively lower infrared cutoff; in the limit where the cutoff is removed we recover the problem of interest. As a test of the formalism, we compute the effective dielectric constant of an homogeneous medium interspersed with randomly located, interpenetrating bubbles. A simple approximation to the renormalization group equations turns out to be equivalent to a self-consistent two-loops evaluation of the effective dielectric constant.

Degradation and depolymerization of plastic waste by local bacterial isolates and bubble column reactor

NASA Astrophysics Data System (ADS)

Hussein, Amal A.; Alzuhairi, Mohammed; Aljanabi, Noor H.

2018-05-01

Accumulation of plastics, especially Polyethylene terephthalate (PET), is an ever increasing ecological threat due to its excessive usage in everyday human life. Nowadays, there are many methods to get rid of plastic wastes including burning, recycling and burying. However, these methods are not very active since their long period, anaerobic conditions that increase the rate of toxic materials released into the environment. This work aims to study the biological degradation of PET microorganism isolated from soil sample. Thirty eight (38) bacterial isolates were isolated from ten soil and plastic waste sample collected from four different waste disposal sites in Baghdad city during different periods between December 2016 and March 2017. Isolation was performed using enrichment culture method (flasks method) by culturing the soil samples in flasks with MSM medium where there is no carbon source only PET. Results showed that Al-Za'farania sample gave a higher number of isolates (13 isolates), while other samples gave less number of isolates. Screening was performed depending on their ability to grow in liquid MSM which contains PET powder and pieces and change the color of the PET-emulsified liquid medium as well as their ability to form the clear zone on PET-MSM agar. The results showed that NH-D-1 isolate has the higher ability to degrade DPET and PET pieces. According to morphological, biochemical characterization and Vitek-2 technique, the most active isolate was identified as Acinetobacter baumannii.

Evidence of fueling of the 2000 new economy bubble by foreign capital inflow: implications for the future of the US economy and its stock market

NASA Astrophysics Data System (ADS)

Sornette, Didier; Zhou, Wei-Xing

2004-02-01

Previous analyses of a large ensemble of stock markets have demonstrated that a log-periodic power law (LPPL) behavior of the prices constitutes a qualifying signature of speculative bubbles that often land with a crash. We detect such a LPPL signature in the foreign capital inflow during the bubble on the US markets culminating in March 2000. We detect a weak synchronization and lag with the NASDAQ LPPL pattern. We propose to rationalize these observations by the existence of positive feedback loops between market-appreciation/increased-spending/increased-deficit-of-balance-of-payment/larger-foreign-surplus/increased-foreign-capital-inflows and so on. Our analysis suggests that foreign capital inflow has been following rather than causing the bubble. We then combine a macroeconomic analysis of feedback processes occurring between the economy and the stock market with a technical analysis of more than 200 years of the DJIA to investigate possible scenarios for the future, three years after the end of the bubble and deep into a bearish regime. We conclude that the low interest rates and depreciating dollar are the indispensable ingredients for a lower sustainable burden of the global US debt structure and for allowing the slow rebuilding of an internationally competitive economy. This will probably be accompanied by a weak stock market on the medium term as the growing Federal deficit is consuming a large part of the foreign surplus dollars and the stock market is remaining a very risky and unattractive investment. Notwithstanding strong surge of liquidity in recent months orchestrated by the Federal Reserve, this macroeconomic analysis which incorporates an element of collective behavior is in line with our recent analyses of the bearish market that started in 2000 in terms of a LPPL “anti-bubble”. We project this LPPL anti-bubble to continue at least for another year. On the short term, increased availability of liquidity (M1) and self-fulfilling bullish anticipations may hold the stock market for a while.

Transport of colloids in unsaturated porous media: A pore-scale observation of processes during the dissolution of air-water interface

NASA Astrophysics Data System (ADS)

Sirivithayapakorn, Sanya; Keller, Arturo

2003-12-01

We present results from pore-scale observations of colloid transport in an unsaturated physical micromodel. The experiments were conducted separately using three different sizes of carboxylate polystyrene latex spheres and Bacteriophage MS2 virus. The main focus was to investigate the pore-scale transport processes of colloids as they interact with the air-water interface (AWI) of trapped air bubbles in unsaturated porous media, as well as the release of colloids during imbibition. The colloids travel through the water phase but are attracted to the AWI by either collision or attractive forces and are accumulated at the AWI almost irreversibly, until the dissolution of the air bubble reduces or eliminates the AWI. Once the air bubbles are near the end of the dissolution process, the colloids can be transported by advective liquid flow, as colloidal clusters. The clusters can then attach to other AWI down-gradient or be trapped in pore throats that would have allowed them to pass through individually. We also observed small air bubbles with attached colloids that traveled through the porous medium during the gas dissolution process. We used Derjaguin-Landau-Verwey-Overbeek (DLVO) theory to help explain the observed results. The strength of the force that holds the colloids at the AWI was estimated, assuming that the capillary force is the major force that holds the colloids at the AWI. Our calculations indicate that the forces that hold the colloids at the AWI are larger than the energy barrier between the colloids. Therefore it is quite likely that the clusters of colloids are formed by the colloids attached at the AWI as they move closer at the end of the bubble dissolution process. Coagulation at the AWI may increase the overall filtration for colloids transported through the vadose zone. Just as important, colloids trapped in the AWI might be quite mobile when the air bubbles are released at the end of the dissolution process, resulting in increased breakthrough. These pore-scale mechanisms are likely to play a significant role in the macroscopic transport of colloids in unsaturated porous media.

Pore level visualization of foam flow in a silicon micromodel. SUPRI TR 100

DOE Office of Scientific and Technical Information (OSTI.GOV)

Woody, F.; Blunt, M.; Castanier, L.

This paper is concerned with the behavior of foam in porous media at the pore level. Identical, heterogeneous silicon micromodels, two dimensionally etched to replicate flow in Berea Sandstone, were used. The models, already saturated with varying concentrations of surfactant and, at times, oil were invaded with air. Visual observations were made of these air displacement events in an effort to determine foam flow characteristics with varying surfactant concentrations, and differing surfactants in the presence of oil. These displacement events were recorded on video tape. These tapes are available at the Stanford University Petroleum Research Institute, Stanford, California. The observedmore » air flow characteristics can be broadly classified into two: continuous and discontinuous. Continuous air flow was observed in two phase runs when the micromodel contained no aqueous surfactant solution. Air followed a tortuous path to the outlet, splitting and reconnecting around grains, isolating water located in dead-end or circumvented pores, all without breaking and forming bubbles. No foam was created. Discontinuous air flow occurred in runs containing surfactant - with smaller bubble sizes appearing with higher surfactant concentrations. Air moved through the medium by way of modified bubble train flow where bubbles travel through pore throats and tend to reside more statically in larger pore bodies until enough force is applied to move them along. The lamellae were stable, and breaking and reforming events by liquid drainage and corner flow were observed in higher surfactant concentrations. However, the classic snap-off process, as described by Roof (1973) was not seen at all.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arévalo, P.; Churazov, E.; Zhuravleva, I.

X-ray images of galaxy clusters and gas-rich elliptical galaxies show a wealth of small-scale features that reflect fluctuations in density and/or temperature of the intracluster medium. In this paper we study these fluctuations in M87/Virgo to establish whether sound waves/shocks, bubbles, or uplifted cold gas dominate the structure. We exploit the strong dependence of the emissivity on density and temperature in different energy bands to distinguish between these processes. Using simulations we demonstrate that our analysis recovers the leading type of fluctuation even in the presence of projection effects and temperature gradients. We confirm the isobaric nature of cool filamentsmore » of gas entrained by buoyantly rising bubbles, extending to 7′ to the east and southwest, and the adiabatic nature of the weak shocks at 40″ and 3′ from the center. For features of ∼5–10 kpc, we show that the central 4′ × 4′ region is dominated by cool structures in pressure equilibrium with the ambient hotter gas while up to 30% of the variance in this region can be ascribed to adiabatic fluctuations. The remaining part of the central 14′ × 14′ region, excluding the arms and shocks described above, is dominated by apparently isothermal fluctuations (bubbles) with a possible admixture (at the level of ∼30%) of adiabatic (sound waves) and by isobaric structures. Larger features, of about 30 kpc, show a stronger contribution from isobaric fluctuations. The results broadly agree with a model based on feedback from an active galactic nucleus mediated by bubbles of relativistic plasma.« less

Estimation of sonodynamic treatment region with sonochemiluminescence in gel phantom

NASA Astrophysics Data System (ADS)

Mashiko, Daisaku; Nishitaka, Shinya; Iwasaki, Ryosuke; Lafond, Maxime; Yoshizawa, Shin; Umemura, Shin-ichiro

2018-07-01

Sonodynamic treatment is a non-invasive cancer treatment using ultrasound through the generation of reactive oxygen species (ROS) by acoustic cavitation. High-intensity focused ultrasound (HIFU) can generate cavitation bubbles using highly negative pressure in its focal region. When cavitation bubbles are forced to collapse, they generate ROS, which can attack cancer cells, typically assisted by a sonodynamically active antitumor agent. For sonodynamic treatment, both localization and efficiency of generating ROS are important. To improve them, the region of ROS generation was quantitatively estimated in this study using a polyacrylamide gel containing luminol as the target exposed to “Trigger HIFU”, consisting of a highly intense short “trigger pulse” to generate a cavitation cloud followed by a moderate-intensity long “sustaining burst” to keep the cavitation bubbles oscillating. It was found to be important for efficient ROS generation that the focal region of the trigger pulse should be immediately exposed to the sustaining burst.

Investigating acoustic-induced deformations in a foam using multiple light scattering.

PubMed

Erpelding, M; Guillermic, R M; Dollet, B; Saint-Jalmes, A; Crassous, J

2010-08-01

We have studied the effect of an external acoustic wave on bubble displacements inside an aqueous foam. The signature of the acoustic-induced bubble displacements is found using a multiple light scattering technique, and occurs as a modulation on the photon correlation curve. Measurements for various sound frequencies and amplitudes are compared to analytical predictions and numerical simulations. These comparisons finally allow us to elucidate the nontrivial acoustic displacement profile inside the foam; in particular, we find that the acoustic wave creates a localized shear in the vicinity of the solid walls holding the foam, as a consequence of inertial contributions. This study of how bubbles "dance" inside a foam as a response to sound turns out to provide new insights on foam acoustics and sound transmission into a foam, foam deformation at high frequencies, and analysis of light scattering data in samples undergoing nonhomogeneous deformations.

The Evolution of the Large-Scale ISM: Bubbles, Superbubbles and Non-Equilibrium Ionization

NASA Astrophysics Data System (ADS)

de Avillez, M. A.; Breitschwerdt, D.

2010-12-01

The ISM, powered by SNe, is turbulent and permeated by a magnetic field (with a mean and a turbulent component). It constitutes a frothy medium that is mostly out of equilibrium and is ram pressure dominated on most of the temperature ranges, except for T < 200 K and T > 106K, where magnetic and thermal pressures dominate, respectively. Such lack of equilibrium is also imposed by the feedback of the radiative processes into the ISM flow. Many models of the ISM or isolated phenomena, such as bubbles, superbubbles, clouds evolution, etc., take for granted that the flow is in the so-called collisional ionization equilibrium (CIE). However, recombination time scales of most of the ions below 106 K are longer than the cooling time scale. This implies that the recombination lags behind and the plasma is overionized while it cools. As a consequence cooling deviates from CIE. This has severe implications on the evolution of the ISM flow and its ionization structure. Here, besides reviewing several models of the ISM, including bubbles and superbubbles, the validity of the CIE approximation is discussed, and a presentation of recent developments in modeling the ISM by taking into account the time-dependent ionization structure of the flow in a full-blown numerical 3D high resolution simulation is presented.

Engineered bio-inspired coating for passive flow control

PubMed Central

Bocanegra Evans, Humberto; Hamed, Ali M.; Gorumlu, Serdar; Doosttalab, Ali; Aksak, Burak; Castillo, Luciano

2018-01-01

Flow separation and vortex shedding are some of the most common phenomena experienced by bluff bodies under relative motion with the surrounding medium. They often result in a recirculation bubble in regions with adverse pressure gradient, which typically reduces efficiency in vehicles and increases loading on structures. Here, the ability of an engineered coating to manipulate the large-scale recirculation region was tested in a separated flow at moderate momentum thickness Reynolds number, Reθ=1,200. We show that the coating, composed of uniformly distributed cylindrical pillars with diverging tips, successfully reduces the size of, and shifts downstream, the separation bubble. Despite the so-called roughness parameter, k+≈1, falling within the hydrodynamic smooth regime, the coating is able to modulate the large-scale recirculating motion. Remarkably, this modulation does not induce noticeable changes in the near-wall turbulence levels. Supported with experimental data and theoretical arguments based on the averaged equations of motion, we suggest that the inherent mechanism responsible for the bubble modulation is essentially unsteady suction and blowing controlled by the increasing cross-section of the tips. The coating can be easily fabricated and installed and works under dry and wet conditions, increasing its potential impact on a diverse range of applications. PMID:29367420

Monitoring of viable airborne SARS virus in ambient air

NASA Astrophysics Data System (ADS)

Agranovski, Igor E.; Safatov, Alexander S.; Pyankov, Oleg V.; Sergeev, Alexander N.; Agafonov, Alexander P.; Ignatiev, Georgy M.; Ryabchikova, Elena I.; Borodulin, Alexander I.; Sergeev, Artemii A.; Doerr, Hans W.; Rabenau, Holger F.; Agranovski, Victoria

Due to recent SARS related issues (Science 300 (5624) 1394; Nature 423 (2003) 240; Science 300 (5627) 1966), the development of reliable airborne virus monitoring procedures has become galvanized by an exceptional sense of urgency and is presently in a high demand (In: Cox, C.S., Wathers, C.M. (Eds.), Bioaerosols Handbook, Lewis Publishers, Boca Raton, FL, 1995, pp. 247-267). Based on engineering control method (Aerosol Science and Technology 31 (1999) 249; 35 (2001) 852), which was previously applied to the removal of particles from gas carriers, a new personal bioaerosol sampler has been developed. Contaminated air is bubbled through porous medium submerged into liquid and subsequently split into multitude of very small bubbles. The particulates are scavenged by these bubbles, and, thus, effectively removed. The current study explores its feasibility for monitoring of viable airborne SARS virus. It was found that the natural decay of such virus in the collection fluid was around 0.75 and 1.76 lg during 2 and 4 h of continuous operation, respectively. Theoretical microbial recovery rates of higher than 55 and 19% were calculated for 1 and 2 h of operation, respectively. Thus, the new sampling method of direct non-violent collection of viable airborne SARS virus into the appropriate liquid environment was found suitable for monitoring of such stress sensitive virus.

Cryptocurrency price drivers: Wavelet coherence analysis revisited

PubMed Central

2018-01-01

Cryptocurrencies have experienced recent surges in interest and price. It has been discovered that there are time intervals where cryptocurrency prices and certain online and social media factors appear related. In addition it has been noted that cryptocurrencies are prone to experience intervals of bubble-like price growth. The hypothesis investigated here is that relationships between online factors and price are dependent on market regime. In this paper, wavelet coherence is used to study co-movement between a cryptocurrency price and its related factors, for a number of examples. This is used alongside a well-known test for financial asset bubbles to explore whether relationships change dependent on regime. The primary finding of this work is that medium-term positive correlations between online factors and price strengthen significantly during bubble-like regimes of the price series; this explains why these relationships have previously been seen to appear and disappear over time. A secondary finding is that short-term relationships between the chosen factors and price appear to be caused by particular market events (such as hacks / security breaches), and are not consistent from one time interval to another in the effect of the factor upon the price. In addition, for the first time, wavelet coherence is used to explore the relationships between different cryptocurrencies. PMID:29668765

Cryptocurrency price drivers: Wavelet coherence analysis revisited.

PubMed

Phillips, Ross C; Gorse, Denise

2018-01-01

Cryptocurrencies have experienced recent surges in interest and price. It has been discovered that there are time intervals where cryptocurrency prices and certain online and social media factors appear related. In addition it has been noted that cryptocurrencies are prone to experience intervals of bubble-like price growth. The hypothesis investigated here is that relationships between online factors and price are dependent on market regime. In this paper, wavelet coherence is used to study co-movement between a cryptocurrency price and its related factors, for a number of examples. This is used alongside a well-known test for financial asset bubbles to explore whether relationships change dependent on regime. The primary finding of this work is that medium-term positive correlations between online factors and price strengthen significantly during bubble-like regimes of the price series; this explains why these relationships have previously been seen to appear and disappear over time. A secondary finding is that short-term relationships between the chosen factors and price appear to be caused by particular market events (such as hacks / security breaches), and are not consistent from one time interval to another in the effect of the factor upon the price. In addition, for the first time, wavelet coherence is used to explore the relationships between different cryptocurrencies.

Passage of a shock wave through inhomogeneous media and its impact on gas-bubble deformation.

PubMed

Nowakowski, A F; Ballil, A; Nicolleau, F C G A

2015-08-01

The paper investigates shock-induced vortical flows within inhomogeneous media of nonuniform thermodynamic properties. Numerical simulations are performed using a Eulerian type mathematical model for compressible multicomponent flow problems. The model, which accounts for pressure nonequilibrium and applies different equations of state for individual flow components, shows excellent capabilities for the resolution of interfaces separating compressible fluids as well as for capturing the baroclinic source of vorticity generation. The developed finite volume Godunov type computational approach is equipped with an approximate Riemann solver for calculating fluxes and handles numerically diffused zones at flow component interfaces. The computations are performed for various initial conditions and are compared with available experimental data. The initial conditions promoting a shock-bubble interaction process include weak to high planar shock waves with a Mach number ranging from 1.2 to 3 and isolated cylindrical bubble inhomogeneities of helium, argon, nitrogen, krypton, and sulphur hexafluoride. The numerical results reveal the characteristic features of the evolving flow topology. The impulsively generated flow perturbations are dominated by the reflection and refraction of the shock, the compression, and acceleration as well as the vorticity generation within the medium. The study is further extended to investigate the influence of the ratio of the heat capacities on the interface deformation.

Orientations for the successful categorization of facial expressions and their link with facial features.

PubMed

Duncan, Justin; Gosselin, Frédéric; Cobarro, Charlène; Dugas, Gabrielle; Blais, Caroline; Fiset, Daniel

2017-12-01

Horizontal information was recently suggested to be crucial for face identification. In the present paper, we expand on this finding and investigate the role of orientations for all the basic facial expressions and neutrality. To this end, we developed orientation bubbles to quantify utilization of the orientation spectrum by the visual system in a facial expression categorization task. We first validated the procedure in Experiment 1 with a simple plaid-detection task. In Experiment 2, we used orientation bubbles to reveal the diagnostic-i.e., task relevant-orientations for the basic facial expressions and neutrality. Overall, we found that horizontal information was highly diagnostic for expressions-surprise excepted. We also found that utilization of horizontal information strongly predicted performance level in this task. Despite the recent surge of research on horizontals, the link with local features remains unexplored. We were thus also interested in investigating this link. In Experiment 3, location bubbles were used to reveal the diagnostic features for the basic facial expressions. Crucially, Experiments 2 and 3 were run in parallel on the same participants, in an interleaved fashion. This way, we were able to correlate individual orientation and local diagnostic profiles. Our results indicate that individual differences in horizontal tuning are best predicted by utilization of the eyes.

Controlled permeation of cell membrane by single bubble acoustic cavitation

PubMed Central

Zhou, Y.; Yang, K.; Cui, J.; Ye, J. Y.; Deng, C. X.

2011-01-01

Sonoporation is the membrane disruption generated by ultrasound and has been exploited as a non-viral strategy for drug and gene delivery. Acoustic cavitation of microbubbles has been recognized to play an important role in sonoporation. However, due to the lack of adequate techniques for precise control of cavitation activities and real-time assessment of the resulting sub-micron process of sonoporation, limited knowledge has been available regarding the detail processes and correlation of cavitation with membrane disruption at the single cell level. In the current study, we developed a combined approach including optical, acoustic, and electrophysiological techniques to enable synchronized manipulation, imaging, and measurement of cavitation of single bubbles and the resulting cell membrane disruption in real-time. Using a self-focused femtosecond laser and high frequency (7.44 MHz) pulses, a single microbubble was generated and positioned at a desired distance from the membrane of a Xenopus oocyte. Cavitation of the bubble was achieved by applying a low frequency (1.5 MHz) ultrasound pulse (duration 13.3 or 40 µs) to induce bubble collapse. Disruption of the cell membrane was assessed by the increase in the transmembrane current (TMC) of the cell under voltage clamp. Simultaneous high-speed bright field imaging of cavitation and measurements of the TMC were obtained to correlate the ultrasound-generated bubble activities with the cell membrane poration. The change in membrane permeability was directly associated with the formation of a sub-micrometer pore from a local membrane rupture generated by bubble collapse or bubble compression depending on ultrasound amplitude and duration. The impact of the bubble collapse on membrane permeation decreased rapidly with increasing distance (D) between the bubble (diameter d) and the cell membrane. The effective range of cavitation impact on membrane poration was determined to be D/d = 0.75. The maximum mean radius of the pores was estimated from the measured TMC to be 0.106 ± 0.032 µm (n = 70) for acoustic pressure of 1.5 MPa (duration 13.3 µs), and increased to 0.171 ± 0.030 µm (n = 125) for acoustic pressure of 1.7 MPa and to 0.182 ± 0.052 µm (n=112) for a pulse duration of 40 µs (1.5 MPa). These results from controlled cell membrane permeation by cavitation of single bubbles revealed insights and key factors affecting sonoporation at the single cell level. PMID:21945682

Ground based studies of thermocapillary flows in levitated drops

NASA Technical Reports Server (NTRS)

Sadhal, Satwindar Singh; Trinh, Eugene H.

1994-01-01

Analytical studies along with ground-based experiments are presently being carried out in connection with thermocapillary phenomena associated with drops and bubbles in a containerless environment. The effort here focuses on the thermal and the fluid phenomena associated with the local heating of acoustically levitated drops, both at 1-g and at low-g. In particular, the Marangoni effect on drops under conditions of local spot-heating and other types of heating are being studied. With the experiments conducted to date, fairly stable acoustic levitation of drops has been achieved and successful flow visualization by light scattering from smoke particles has been carried out. The results include situations with and without heating. As a preliminary qualitative interpretation of these experimental results, we consider the external flow pattern as a superposition of three discrete circulation cells operating on different spatial scales. The observations of the flow fields also indicate the existence of a steady state torque induced by the streaming flows. The theoretical studies have been concentrated on the analysis of streaming flows in a gaseous medium with the presence of a spherical particle undergoing periodic heating. A matched asymptotic analysis was carried out for small parameters derived from approximations in the high frequency range. The heating frequency being 'in tune' with the acoustic frequency results in a nonzero time-averaged thermal field. This leads to a steady heat flow across the equatorial plane of the sphere.

Characterization of different bubble formulations for blood-brain barrier opening using a focused ultrasound system with acoustic feedback control.

PubMed

Bing, Chenchen; Hong, Yu; Hernandez, Christopher; Rich, Megan; Cheng, Bingbing; Munaweera, Imalka; Szczepanski, Debra; Xi, Yin; Bolding, Mark; Exner, Agata; Chopra, Rajiv

2018-05-22

Focused ultrasound combined with bubble-based agents serves as a non-invasive way to open the blood-brain barrier (BBB). Passive acoustic detection was well studied recently to monitor the acoustic emissions induced by the bubbles under ultrasound energy, but the ability to perform reliable BBB opening with a real-time feedback control algorithm has not been fully evaluated. This study focuses on characterizing the acoustic emissions of different types of bubbles: Optison, Definity, and a custom-made nanobubble. Their performance on reliable BBB opening under real-time feedback control based on acoustic detection was evaluated both in-vitro and in-vivo. The experiments were conducted using a 0.5 MHz focused ultrasound transducer with in-vivo focal pressure ranges from 0.1-0.7 MPa. Successful feedback control was achieved with all three agents when combining with infusion injection. Localized opening was confirmed with Evans blue dye leakage. Microscopic images were acquired to review the opening effects. Under similar total gas volume, nanobubble showed a more reliable opening effect compared to Optison and Definity (p < 0.05). The conclusions obtained from this study confirm the possibilities of performing stable opening using a feedback control algorithm combined with infusion injection. It also opens another potential research area of BBB opening using sub-micron bubbles.

Examination of laser microbeam cell lysis in a PDMS microfluidic channel using time-resolved imaging

PubMed Central

Quinto-Su, Pedro A.; Lai, Hsuan-Hong; Yoon, Helen H.; Sims, Christopher E.; Allbritton, Nancy L.; Venugopalan, Vasan

2008-01-01

We use time-resolved imaging to examine the lysis dynamics of non-adherent BAF-3 cells within a microfluidic channel produced by the delivery of single highly-focused 540 ps duration laser pulses at λ = 532 nm. Time-resolved bright-field images reveal that the delivery of the pulsed laser microbeam results in the formation of a laser-induced plasma followed by shock wave emission and cavitation bubble formation. The confinement offered by the microfluidic channel constrains substantially the cavitation bubble expansion and results in significant deformation of the PDMS channel walls. To examine the cell lysis and dispersal of the cellular contents, we acquire time-resolved fluorescence images of the process in which the cells were loaded with a fluorescent dye. These fluorescence images reveal cell lysis to occur on the nanosecond to microsecond time scale by the plasma formation and cavitation bubble dynamics. Moreover, the time-resolved fluorescence images show that while the cellular contents are dispersed by the expansion of the laser-induced cavitation bubble, the flow associated with the bubble collapse subsequently re-localizes the cellular contents to a small region. This capacity of pulsed laser microbeam irradiation to achieve rapid cell lysis in microfluidic channels with minimal dilution of the cellular contents has important implications for their use in lab-on-a-chip applications. PMID:18305858

Impact sensitivity test of liquid energetic materials

NASA Astrophysics Data System (ADS)

Tiutiaev, A.; Dolzhikov, A.; Zvereva, I.

2017-10-01

This paper presents new experimental method for sensitivity evaluation at the impact. A large number of researches shown that the probability of explosion initiating of liquid explosives by impact depends on the chemical nature and the various external characteristics. But the sensitivity of liquid explosive in the presence of gas bubbles increases many times as compared with the liquid without gas bubbles. In this case local chemical reaction focus are formed as a result of compression and heating of the gas inside the bubbles. In the liquid as a result of convection, wave motion, shock, etc. gas bubbles are easily generated, it is necessary to develop methods for determining sensitivity of liquid explosives to impact and to research the explosives ignition with bubbles. For the experimental investigation, the well-known impact machine and the so-called appliance 1 were used. Instead of the metal cup in the standard method in this paper polyurethane foam cylindrical container with liquid explosive was used. Polyurethane foam cylindrical container is easily deforms by impact. A large number of tests with different liquid explosives were made. It was found that the test liquid explosive to impact in appliance 1 with polyurethane foam to a large extent reflect the real mechanical sensitivity due to the small loss of impact energy on the deformation of the metal cup, as well as the best differentiation liquid explosive sensitivity due to the higher resolution method.

The Mesoscale Ionospheric Simulation Testbed (MIST) Regional Data Assimilation Model (Invited)

NASA Astrophysics Data System (ADS)

Comberiate, J.; Kelly, M. A.; Miller, E.; Paxton, L.

2013-12-01

The Mesoscale Ionospheric Simulation Testbed (MIST) provides a regional nowcast and forecast of electron density values and has sufficient resolution to include equatorial plasma bubbles. The SSUSI instrument on the DMSP F18 satellite has high-resolution nightly observations of plasma bubbles at 8 PM local time throughout the current solar maximum. MIST can assimilate SSUSI UV observations, GPS TEC measurements, and SCINDA S4 readings simultaneously into a single scintillation map over a region of interest. MIST also models ionospheric physics to provide a short-term UHF scintillation forecast based on assimilated data. We will present examples of electron density and scintillation maps from MIST. We will also discuss the potential to predict scintillation occurrence up to 6 hours in advance using observations of the equatorial arcs from SSUSI observations at 5:30 PM local time on the DMSP F17 satellite.

Localization of puroindoline-a and lipids in bread dough using confocal scanning laser microscopy.

PubMed

Dubreil, Laurence; Biswas, Samares C; Marion, Didier

2002-10-09

Puroindolines are lipid-binding proteins from wheat flour that play a significant role in bread crumb texture. The localization of wheat flour lipids and puroindoline-a (PIN-a) in bread dough was studied by confocal scanning laser microscopy (CSLM). Wheat lipids were located around gas cells (GC) and embedded within the protein-starch matrix (SPM) of the dough. PIN-a was mainly located in the matrix of dough, where it was associated with lipids. In contrast, in defatted dough, PIN-a was found around GC. Addition of puroindolines in bread dough induced a defatting of the gas bubble surface and a decrease of the lipid vesicles and/or droplet size embedded within the SPM. Therefore, puroindolines control the lipid partitioning within the different phases of dough, a phenomenon that should have important consequence on the gas bubble expansion and GC formation in the further stages (fermentation, baking) of the bread-making process.

Observation of a cavitation cloud in tissue using correlation between ultrafast ultrasound images.

PubMed

Prieur, Fabrice; Zorgani, Ali; Catheline, Stefan; Souchon, Rémi; Mestas, Jean-Louis; Lafond, Maxime; Lafon, Cyril

2015-07-01

The local application of ultrasound is known to improve drug intake by tumors. Cavitating bubbles are one of the contributing effects. A setup in which two ultrasound transducers are placed confocally is used to generate cavitation in ex vivo tissue. As the transducers emit a series of short excitation bursts, the evolution of the cavitation activity is monitored using an ultrafast ultrasound imaging system. The frame rate of the system is several thousands of images per second, which provides several tens of images between consecutive excitation bursts. Using the correlation between consecutive images for speckle tracking, a decorrelation of the imaging signal appears due to the creation, fast movement, and dissolution of the bubbles in the cavitation cloud. By analyzing this area of decorrelation, the cavitation cloud can be localized and the spatial extent of the cavitation activity characterized.

Development and performance evaluation of air fine bubbles on water quality of thai catfish rearing

NASA Astrophysics Data System (ADS)

Subhan, Ujang; Muthukannan, Vanitha; Azhary, Sundoro Yoga; Mulhadi, Muhammad Fakhri; Rochima, Emma; Panatarani, Camellia; Joni, I. Made

2018-02-01

The efficiency and productivity of aquaculture strongly depends on the development of advanced technology for water quality management system. The most important factor for the success of intensive aquaculture system is controlling the water quality of fish rearing media. This paper reports the design of fine bubbles (FBs) generator and performance evaluation of the system to improve water quality in thai catfish media (10 g/ind) with density (16.66 ind./L). The FBs generator was designed to control the size distribution of bubble by controlling its air flow rate entry to the mixing chamber of the generator. The performance of the system was evaluated based on the produced debit, dissolved oxygen rate and ammonia content in the catfish medium. The size distribution was observed by using a high speed camera image followed by processing using ImageJ. freeware application. The results show that air flow rate 0.05 L/min and 0.1 L/min received average bubble size of 29 µm and 31 µm respectively. The generator produced bubbles with capacity of 6 L/min and dissolved oxygen rate 0.2 ppm/min/L. The obtained DO growth was 0.455 ppm/second/L while the average decay rate was 0.20 ppm/second/L. (0.011/0.005 fold). In contrast, the recieved DO growth rate is faster compared to the DO consumption rate of the Thai catfish. This results indicated that the potential application of FBs enhanced the density of thai catfish seed rearing. In addition, ammonia can be reduced at 0.0358 ppm/hour/L and it is also observed that the inhibition of bacterial growth of air FBs is postive to Aeromonas hydrophila bacteria compared to the negative control. It is concluded that as-developed FBs system can be potentially applied for intensive thai catfish culture and expected to improve the feeding efficiency rate.

A dynamic pressure view cell for acoustic stimulation of fluids--Micro-bubble generation and fluid movement in porous media.

PubMed

Stewart, Robert A; Shaw, J M

2015-09-01

The development and baseline operation of an acoustic view cell for observing fluids, and fluid-fluid and fluid-solid interfaces in porous media over the frequency range of 10-5000 Hz is described. This range includes the industrially relevant frequency range 500-5000 Hz that is not covered by existing devices. Pressure waveforms of arbitrary shape are generated in a 17.46 mm ID by 200 mm and 690.5 mm long glass tubes at flow rates up to 200 ml/min using a syringe pump. Peak-to-peak amplitudes exceeding 80 kPa are readily realized at frequencies from 10 to 5000 Hz in bubble free fluids when actuated with 20 Vpp as exemplified using castor oil. At resonant frequencies, peak-to-peak pressure amplitudes exceeding 500 kPa were obtained (castor oil at 2100 Hz when actuated with 20 Vpp). Impacts of vibration on macroscopic liquid-liquid and liquid-vapour interfaces and interface movement are illustrated. Pressure wave transmission and attenuation in a fluid saturated porous medium, randomly packed 250-330 μm spherical silica beads, is also demonstrated. Attenuation differences and frequency shifts in resonant peaks are used to detect the presence and generation of dispersed micro-bubbles (<180 μm diameter), and bubbles within porous media that are not readily visualized. Envisioned applications include assessment of the impacts of vibration on reaction, mass transfer, and flow/flow pattern outcomes. This knowledge will inform laboratory and pilot scale process studies, where nuisance vibrations may affect the interpretation of process outcomes, and large scale or in situ processes in aquifers or hydrocarbon reservoirs where imposed vibration may be deployed to improve aspects of process performance. Future work will include miscible interface observation and quantitative measurements in the bulk and in porous media where the roles of micro-bubbles comprise subjects of special interest.

A new method of derived equatorial plasma bubbles motion by tracing OI 630 nm emission all-sky images

NASA Astrophysics Data System (ADS)

Li, M.; Yu, T.; Chunliang, X.; Zuo, X.; Liu, Z.

2017-12-01

A new method for estimating the equatorial plasma bubbles (EPBs) motions from airglow emission all-sky images is presented in this paper. This method, which is called 'cloud-derived wind technology' and widely used in satellite observation of wind, could reasonable derive zonal and meridional velocity vectors of EPBs drifts by tracking a series of successive airglow 630.0 nm emission images. Airglow emission images data are available from an all sky airglow camera in Hainan Fuke (19.5°N, 109.2°E) supported by China Meridional Project, which can receive the 630.0nm emission from the ionosphere F region at low-latitudes to observe plasma bubbles. A series of pretreatment technology, e.g. image enhancement, orientation correction, image projection are utilized to preprocess the raw observation. Then the regions of plasma bubble extracted from the images are divided into several small tracing windows and each tracing window can find a target window in the searching area in following image, which is considered as the position tracing window moved to. According to this, velocities in each window are calculated by using the technology of cloud-derived wind. When applying the cloud-derived wind technology, the maximum correlation coefficient (MCC) and the histogram of gradient (HOG) methods to find the target window, which mean to find the maximum correlation and the minimum euclidean distance between two gradient histograms in respectively, are investigated and compared in detail. The maximum correlation method is fianlly adopted in this study to analyze the velocity of plasma bubbles because of its better performance than HOG. All-sky images from Hainan Fuke, between August 2014 and October 2014, are analyzed to investigate the plasma bubble drift velocities using MCC method. The data at different local time at 9 nights are studied and find that zonal drift velocity in different latitude at different local time ranges from 50 m/s to 180 m/s and there is a peak value at about 20°N. For comparison and validation, EPBs motions obtained from three traditional methods are also investigated and compared with MC method. The advantages and disadvantages of using cloud-derived wind technology to calculate EPB drift velocity are discussed.

Observational Evidence For The Comet-Like Heliosphere

NASA Astrophysics Data System (ADS)

Bzowski, M.; Czechowski, A.; Funsten, H. O.; Grygorczuk, J.; Heerikhuisen, J.; Kubiak, M. A.; Moebius, E.; McComas, D. J.; Schwadron, N.; Sokol, J. M.; Swaczyna, P.; Zirnstein, E.

2017-12-01

The shape of the heliosphere is a subject of ongoing debate. The traditional comet-like image has recently been challenged by ideas of croissant- or bubble-like forms. Here we seek to resolve this debate by confronting available observational evidence with global modeling. Several MHD models of a comet-like heliosphere were used to simulate the radius and center of the IBEX Ribbon to fit the direction and intensity of the interstellar magnetic field (ISMF). These models assumed the secondary ENA emission mechanism, which was recently strengthened due to direct measurement of the distance to the Ribbon source most likely just beyond the heliopause. The same mechanism explains the dependence of the Ribbon center position on energy due to the latitudinal structure of solar wind. The obtained ISMF vector agrees among these models and is consistent with the draped IMF measured by Voyager. Independently, we have shown by modeling that the Warm Breeze discovered by IBEX is naturally created in the outer heliosheath due to charge-exchange between interstellar He+ ions and He atoms. Now we simulate the Warm Breeze for various directions and intensities of the local IMF and we find that the simulation results are in best agreement with IBEX observations for the IMF vector obtained from the above-mentioned Ribbon analyses and Voyager measurements. These arguments, along with the co-planarity of the inflow directions of interstellar neutral H, He, O, and the Warm Breeze, directions of the Ribbon center and ISMF, as well as measurements of the plasma flow directions in the IHS by Voyager 2 indicate the existence of a common plane of approximate mirror symmetry of the heliosphere, defined by the directions of ISMF and the Sun's motion through the local interstellar medium. This suggests that the global structure of the outer heliosphere mostly results from the conditions in the local interstellar medium and the Sun's velocity. This evidence, obtained from very different spacecraft and measurement techniques, supports a homogeneous and consistent picture of the heliosphere with a comet-like shape and organized by the plane of approximate mirror symmetry.

XMM-Newton Observations of MBM 12: More Constraints on the Solar Wind Charge Exchange and Local Bubble Emissions

NASA Technical Reports Server (NTRS)

Koutroumpa, Dimitra; Smith, Randall K.; Edgar, Richard J.; Kuntz, Kip D.; Plucinsky, Paul P.; Snowden, Steven L.

2010-01-01

We present the first analysis of an XMM-Newton observation of the nearby molecular cloud MBM 12. We find that in the direction of MBM 12 the total O VII (0.57 keV) triplet emission is 1.8(+0.5/-0.6) photons/sq cm/s/sr (or Line Units - LU) while for the O VIII (0.65 keV) line emission we find a 3(sigma) upper limit of <1 LU. We also use a heliospheric model to calculate the O VII and O VIII emission generated by Solar Wind Charge-eXchange (SWCX) which we compare to the XMM-Newton observations. This comparison provides new constraints on the relative heliospheric and Local Bubble contributions to the local diffuse X-ray background. The heliospheric SWCX model predicts 0.82 LU for O VII, which accounts for approx. 46+/-15% of the observed value, and 0.33 LU for the O VIII line emission consistent with the XMM-Newton observed value. We discuss our results in combination with previous observations of the MBM 12 with CHANDRA and Suzaku.

Time reversal technique for gas leakage detection.

PubMed

Maksimov, A O; Polovinka, Yu A

2015-04-01

The acoustic remote sensing of subsea gas leakage traditionally uses sonars as active acoustic sensors and hydrophones picking up the sound generated by a leak as passive sensors. When gas leaks occur underwater, bubbles are produced and emit sound at frequencies intimately related to their sizes. The experimental implementation of an acoustic time-reversal mirror (TRM) is now well established in underwater acoustics. In the basic TRM experiment, a probe source emits a pulse that is received on an array of sensors, time reversed, and re-emitted. After time reversal, the resulting field focuses back at the probe position. In this study, a method for enhancing operation of the passive receiving system has been proposed by using it in the regime of TRM. Two factors, the local character of the acoustic emission signal caused by the leakage and a resonant nature of the bubble radiation at their birth, make particularly effective scattering with the conjugate wave (CW). Analytical calculations are performed for the scattering of CW wave on a single bubble when CW is formed by bubble birthing wail received on an array, time reversed, and re-emitted. The quality of leakage detection depends on the spatio-temporal distribution of ambient noise.

Interfacial Dynamics of Condensing Vapor Bubbles in an Ultrasonic Acoustic Field

NASA Astrophysics Data System (ADS)

Boziuk, Thomas; Smith, Marc; Glezer, Ari

2016-11-01

Enhancement of vapor condensation in quiescent subcooled liquid using ultrasonic actuation is investigated experimentally. The vapor bubbles are formed by direct injection from a pressurized steam reservoir through nozzles of varying characteristic diameters, and are advected within an acoustic field of programmable intensity. While kHz-range acoustic actuation typically couples to capillary instability of the vapor-liquid interface, ultrasonic (MHz-range) actuation leads to the formation of a liquid spout that penetrates into the vapor bubble and significantly increases its surface area and therefore condensation rate. Focusing of the ultrasonic beam along the spout leads to ejection of small-scale droplets from that are propelled towards the vapor liquid interface and result in localized acceleration of the condensation. High-speed video of Schlieren images is used to investigate the effects of the ultrasonic actuation on the thermal boundary layer on the liquid side of the vapor-liquid interface and its effect on the condensation rate, and the liquid motion during condensation is investigated using high-magnification PIV measurements. High-speed image processing is used to assess the effect of the actuation on the dynamics and temporal variation in characteristic scale (and condensation rate) of the vapor bubbles.

Coalescence preference in dense packing of bubbles

NASA Astrophysics Data System (ADS)

Kim, Yeseul; Gim, Bopil; Gim, Bopil; Weon, Byung Mook

2015-11-01

Coalescence preference is the tendency that a merged bubble from the contact of two original bubbles (parent) tends to be near to the bigger parent. Here, we show that the coalescence preference can be blocked by densely packing of neighbor bubbles. We use high-speed high-resolution X-ray microscopy to clearly visualize individual coalescence phenomenon which occurs in micro scale seconds and inside dense packing of microbubbles with a local packing fraction of ~40%. Previous theory and experimental evidence predict a power of -5 between the relative coalescence position and the parent size. However, our new observation for coalescence preference in densely packed microbubbles shows a different power of -2. We believe that this result may be important to understand coalescence dynamics in dense packing of soft matter. This work (NRF-2013R1A22A04008115) was supported by Mid-career Researcher Program through NRF grant funded by the MEST and also was supported by Ministry of Science, ICT and Future Planning (2009-0082580) and by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry and Education, Science and Technology (NRF-2012R1A6A3A04039257).

TEM Characterization of High Burn-up Microstructure of U-7Mo Alloy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jian Gan; Brandon Miller; Dennis Keiser

2014-04-01

As an essential part of global nuclear non-proliferation effort, the RERTR program is developing low enriched U-Mo fuels (< 20% U-235) for use in research and test reactors that currently employ highly enriched uranium fuels. One type of fuel being developed is a dispersion fuel plate comprised of U-7Mo particles dispersed in Al alloy matrix. Recent TEM characterizations of the ATR irradiated U-7Mo dispersion fuel plates include the samples with a local fission densities of 4.5, 5.2, 5.6 and 6.3 E+21 fissions/cm3 and irradiation temperatures of 101-136?C. The development of the irradiated microstructure of the U-7Mo fuel particles consists ofmore » fission gas bubble superlattice, large gas bubbles, solid fission product precipitates and their association to the large gas bubbles, grain subdivision to tens or hundreds of nanometer size, collapse of bubble superlattice, and amorphisation. This presentation will describe the observed microstructures specifically focusing on the U-7Mo fuel particles. The impact of the observed microstructure on the fuel performance and the comparison of the relevant features with that of the high burn-up UO2 fuels will be discussed.« less

Resolution limits of ultrafast ultrasound localization microscopy

NASA Astrophysics Data System (ADS)

Desailly, Yann; Pierre, Juliette; Couture, Olivier; Tanter, Mickael

2015-11-01

As in other imaging methods based on waves, the resolution of ultrasound imaging is limited by the wavelength. However, the diffraction-limit can be overcome by super-localizing single events from isolated sources. In recent years, we developed plane-wave ultrasound allowing frame rates up to 20 000 fps. Ultrafast processes such as rapid movement or disruption of ultrasound contrast agents (UCA) can thus be monitored, providing us with distinct punctual sources that could be localized beyond the diffraction limit. We previously showed experimentally that resolutions beyond λ/10 can be reached in ultrafast ultrasound localization microscopy (uULM) using a 128 transducer matrix in reception. Higher resolutions are theoretically achievable and the aim of this study is to predict the maximum resolution in uULM with respect to acquisition parameters (frequency, transducer geometry, sampling electronics). The accuracy of uULM is the error on the localization of a bubble, considered a point-source in a homogeneous medium. The proposed model consists in two steps: determining the timing accuracy of the microbubble echo in radiofrequency data, then transferring this time accuracy into spatial accuracy. The simplified model predicts a maximum resolution of 40 μm for a 1.75 MHz transducer matrix composed of two rows of 64 elements. Experimental confirmation of the model was performed by flowing microbubbles within a 60 μm microfluidic channel and localizing their blinking under ultrafast imaging (500 Hz frame rate). The experimental resolution, determined as the standard deviation in the positioning of the microbubbles, was predicted within 6 μm (13%) of the theoretical values and followed the analytical relationship with respect to the number of elements and depth. Understanding the underlying physical principles determining the resolution of superlocalization will allow the optimization of the imaging setup for each organ. Ultimately, accuracies better than the size of capillaries are achievable at several centimeter depths.

49 CFR 611.305 - Small Starts local financial commitment criteria.

Code of Federal Regulations, 2014 CFR

2014-10-01

...,” “medium-high,” “medium,” “medium-low,” or “low.” The process by which the summary local financial... 49 Transportation 7 2014-10-01 2014-10-01 false Small Starts local financial commitment criteria... Starts § 611.305 Small Starts local financial commitment criteria. In order to approve a grant under 49 U...

49 CFR 611.305 - Small Starts local financial commitment criteria.

Code of Federal Regulations, 2013 CFR

2013-10-01

...,” “medium-high,” “medium,” “medium-low,” or “low.” The process by which the summary local financial... 49 Transportation 7 2013-10-01 2013-10-01 false Small Starts local financial commitment criteria... Starts § 611.305 Small Starts local financial commitment criteria. In order to approve a grant under 49 U...

Getting the gas out - developing gas networks in magmatic systems

NASA Astrophysics Data System (ADS)

Cashman, Katharine; Rust, Alison; Oppenheimer, Julie; Belien, Isolde

2015-04-01

Volcanic eruption style, and explosive potential, are strongly controlled by the pre-eruptive history of the magmatic volatiles: specifically, the more efficient the gas loss prior to eruption, the lower the likelihood of primary (magmatic) explosive activity. Commonly considered gas loss mechanisms include separated flow, where individual bubbles (or bubble clouds) travel at a rate that is faster than the host magma, and permeable flow, where gas escapes through permeable (connected) pathways developed within a (relatively) static matrix. Importantly, gas loss via separated flow is episodic, while gas loss via permeable flow is likely to be continuous. Analogue experiments and numerical models on three phase (solid-liquid-gas) systems also suggest a third mechanism of gas loss that involves the opening and closing of 'pseudo fractures'. Pseudo fractures form at a critical crystallinity that is close to the maximum particle packing. Fractures form by local rearrangement of solid particles and liquid to form a through-going gas fracture; gas escape is episodic, and modulated by the available gas volume and the rate of return flow of interstitial liquid back into the fracture. In all of the gas escape scenarios described above, a fundamental control on gas behaviour is the melt viscosity, which affects the rate of individual bubble rise, the rate of bubble expansion, the rate of film thinning (required for bubble coalescence), and the rate of melt flow into gas-generated fractures. From the perspective of magma degassing, rates of gas expansion and film thinning are key to the formation of an interconnected (permeable) gas pathway. Experiments with both analogue and natural materials show that bubble coalescence is relatively slow, and, in particle-poor melts, does not necessarily create permeable gas networks. As a result, degassing efficiency is modulated by the time scales required either (1) to produce large individual bubbles or bubble clouds (in low viscosity melts) or (2) to develop sufficient porosity for full connectivity of a bubble network (in high viscosity melts). In contrast, our experiments suggest that the presence of solid particles may greatly enhance gas escape. On the one hand, the addition of solid particles increases the bulk viscosity of the mixture, which reduces the migration rate of large single bubbles. On the other hand, the strength of networks created by touching crystals inhibits bulk magma deformation and forces smaller bubbles to deform to occupy the spaces between particles, thereby increasing both the bubble shape anisotropy and, correspondingly, the probability of bubble coalescence. Gas pathways created in this way take advantage of inhomogeneities in the spatial distribution of crystals and allow large-scale gas release at relatively low vesicularities. This mechanism of gas escape is likely to be important not only in mafic arc volcanoes, where shallow conduits are likely to be highly crystalline, but also for degassing of crystal-mush-dominated magmatic systems.

Intense gas bubble emissions in the Kerch seep area - A newly discovered high-flux seep site in the Black Sea

NASA Astrophysics Data System (ADS)

Römer, M.; Sahling, H.; Pape, T.; Bahr, A.; Feseker, T.; Wintersteller, P.; Bohrmann, G.

2012-04-01

More than 500 bubble-induced hydroacoustic anomalies (flares) were found in the water column above the seafloor in the study area comprising about 430 km2 at the Don-Kuban paleo-fan (Eastern Black Sea) by using ship mounted single beam and multibeam echosounders. Almost all flares originated from the seafloor above the gas hydrate stability zone (GHSZ), which in that region is located below ~700 m water depth. This observation confirms the sealing mechanism of gas hydrate, which impedes migration of free gas through the GHSZ and subsequent bubble emission from the seafloor. However, an intense seep site, called the "Kerch seep area" was discovered as an exception at 890 m water depth well within the GHSZ. In situ temperature measurements in shallow sediments indicate locally elevated temperatures probably caused by enhanced upward fluid flow. The base of the GHSZ in this region is generally situated at about 150 m below the seafloor. However, the local thermal anomalies result in a thinning of the gas hydrate occurrence zone to only a few meters below the seafloor and allow free gas to reach the seafloor. At sites where gas migrated into near-surface deposits, shallow gas hydrate deposits evolved and up-doming of overlying sediments led to the formation of mounds rising several meters from the surrounding seafloor. Further gas bubbles ascending from greater depth are accumulated below the gas hydrate layer at the base of the mound structures and migrate horizontally to their rims. At the mound edges gas bubbles either might form fresh gas hydrates and increase the extent of the mound structures by pushing up overlying sediments or escape at several sites into the water column. Two mounds were mapped in ultra-high resolution during dives with the autonomous underwater vehicle 'AUV MARUM SEAL 5000'. Several individual flares were detected in the Kerch seep area using hydroacoustic systems. Repeated surveys in that area conducted during three cruises within four years suggested that gas discharge varied spatially and temporally while the total number of flares remained rather constant. During seafloor inspections with MARUḾs remotely operated vehicle 'ROV QUEST 4000 m' gas bubble emission sites were investigated in detail. Gas bubbles collected during the ROV dives mainly consisted of methane predominantly of microbial origin. By analyzing the high-definition video material the gas flux from several bubble emission sites was calculated. In combination with the hydroacoustic results (flare distributions) it is estimated that about 2.2 - 87 × 106 mol CH4/yr are emitted from the seafloor at the Kerch seep area. Despite this high mass of methane injected into the hydrosphere, the peak of the highest flares at ~350 m water depth as revealed by echosounder recording suggest that the ascending methane completely dissolves in the water column and does not pass the sea-atmosphere boundary.

A Generalized Eulerian-Lagrangian Analysis, with Application to Liquid Flows with Vapor Bubbles

NASA Technical Reports Server (NTRS)

Dejong, Frederik J.; Meyyappan, Meyya

1993-01-01

Under a NASA MSFC SBIR Phase 2 effort an analysis has been developed for liquid flows with vapor bubbles such as those in liquid rocket engine components. The analysis is based on a combined Eulerian-Lagrangian technique, in which Eulerian conservation equations are solved for the liquid phase, while Lagrangian equations of motion are integrated in computational coordinates for the vapor phase. The novel aspect of the Lagrangian analysis developed under this effort is that it combines features of the so-called particle distribution approach with those of the so-called particle trajectory approach and can, in fact, be considered as a generalization of both of those traditional methods. The result of this generalization is a reduction in CPU time and memory requirements. Particle time step (stability) limitations have been eliminated by semi-implicit integration of the particle equations of motion (and, for certain applications, the particle temperature equation), although practical limitations remain in effect for reasons of accuracy. The analysis has been applied to the simulation of cavitating flow through a single-bladed section of a labyrinth seal. Models for the simulation of bubble formation and growth have been included, as well as models for bubble drag and heat transfer. The results indicate that bubble formation is more or less 'explosive'. for a given flow field, the number density of bubble nucleation sites is very sensitive to the vapor properties and the surface tension. The bubble motion, on the other hand, is much less sensitive to the properties, but is affected strongly by the local pressure gradients in the flow field. In situations where either the material properties or the flow field are not known with sufficient accuracy, parametric studies can be carried out rapidly to assess the effect of the important variables. Future work will include application of the analysis to cavitation in inducer flow fields.

Horizontally rotated cell culture system with a coaxial tubular oxygenator

NASA Technical Reports Server (NTRS)

Wolf, David A. (Inventor); Schwarz, Ray P. (Inventor); Trinh, Tinh T. (Inventor)

1991-01-01

The present invention relates to a horizontally rotating bioreactor useful for carrying out cell and tissue culture. For processing of mammalian cells, the system is sterilized and fresh fluid medium, microcarrier beads, and cells are admitted to completely fill the cell culture vessel. An oxygen containing gas is admitted to the interior of the permeable membrane which prevents air bubbles from being introduced into the medium. The cylinder is rotated at a low speed within an incubator so that the circular motion of the fluid medium uniformly suspends the microbeads throughout the cylinder during the cell growth period. The unique design of this cell and tissue culture device was initially driven by two requirements imposed by its intended use for feasibility studies for three dimensional culture of living cells and tissues in space by JSC. They were compatible with microgravity and simulation of microgravity in one G. The vessels are designed to approximate the extremely quiescent low shear environment obtainable in space.

A novel bubble-forming material for preparing hydrophobic-agent-loaded bubbles with theranostic functionality.

PubMed

Yang, Pei-Sin; Tung, Fu-I; Chen, Hsiao-Ping; Liu, Tse-Ying; Lin, Yi-Ying

2014-08-01

In the present study, a new bubble-forming material (carboxymethyl hexanoyl chitosan, CHC), together with superparamagnetic iron oxide (SPIO) nanoparticles, was employed to prepare image-guided bubbles for efficiently encapsulating and delivering hydrophobic agents to kill tumor cells. The results showed that CHC could be used for preparing not only micronized bubbles (CHC/SPIO MBs) to exhibit ultrasound imaging functionality but also nanosized bubbles (CHC/SPIO NBs) to exhibit magnetic resonance T2 image contrast. It was found that the amounts of SPIO nanoparticles and hexane during preparation process were the key factors to obtaining CHC/SPIO NBs. Most importantly, under in vitro cell culture conditions with the same amount of camptothecin (CPT) and therapeutic sonication, CPT-loaded CHC/SPIO NBs demonstrated more significant transcellular delivery and cytotoxicity than free CPT. Subsequently, an intratumoral injection was proposed for the in vivo administration of hydrophobic-agent-loaded CHC/SPIO NBs. After injection, the distribution of a hydrophobic dye (DiR, an agent with near-infrared (NIR) fluorescence used as a model drug) released from the CHC/SPIO NBs was tracked by an NIR imaging technique. A significant tumor-specific accumulation was observed in the mouse that received the DiR-loaded CHC/SPIO NBs; the same was not observed in the mouse that received the free dye (without incorporating with CHC/SPIO NBs). It is expected, in the future, both the dose of the therapeutic agent administered and its side effects can be significantly lowered by using novel CHC/SPIO NBs together with local delivery (intratumoral injection), targeted imaging and enhanced cellular uptake of the drug. Copyright © 2014 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

Amplification of seismic waves beneath active volcanoes

NASA Astrophysics Data System (ADS)

Navon, O.; Lensky, N. G.; Collier, L.; Neuberg, J.; Lyakhovsky, V.

2003-04-01

Long-period (LP) seismic events are typical of many volcanoes and are attributed to energy leaking from waves traveling through the volcanic conduit or along the conduit - country-rock interface. The LP events are triggered locally, at the volcanic edifice, but the source of energy for the formation of tens of events per day is not clear. Energy may be supplied by volatile-release from a supersaturated melt. If bubbles are present in equilibrium with the melt in the conduit, and the melt is suddenly decompressed, transfer of volatiles from the supersaturated melt into the bubbles transforms stored potential energy into expansion work. For example, small dome collapses may decompress the conduit by a few bars and lead to solubility decrease, exsolution of volatiles and, consequently, to work done by the expansion of the bubbles under pressure. This energy is released over a timescale that is similar to that of LP events and may amplify the original weak seismic signals associated with the collapse. Using the formulation of Lensky et al. (2002), following the decompression, when the transfer of volatiles into bubbles is fast enough, expansion accelerates and the bulk viscosity of the bubbly magma is negative. New calculations show that under such conditions a sinusoidal P-wave is amplified. We note that seismic waves created by tectonic earthquakes that are not associated with net decompression, do not lead to net release of volatiles or to net expansion. In this case, the bulk viscosity is positive and waves traveling through the magma should attenuate. The proposed model explains how weak seismic signals may be amplified as they travel through a conduit that contains supersaturated bubbly magma. It provides the general framework for amplifying volcanic seismicity such as the signals associated with long-period events.

The Dependence of the Ultrasound-Induced Blood-Brain Barrier Opening Characteristics on Microbubble Size In Vivo

NASA Astrophysics Data System (ADS)

Choi, James J.; Feshitan, Jameel A.; Wang, Shougang; Tung, Yao-Sheng; Baseri, Babak; Borden, Mark A.; Konofagou, Elisa E.

2009-04-01

Recent neuropharmaceutical developments have led to potent disease-modifying drugs. In spite of these advancements, most agents cannot traverse the blood-brain barrier (BBB) and deposit in the brain. Focused ultrasound (FUS) with microbubbles has been shown to induce noninvasive, localized, and transient BBB opening. Although promising, safety and efficacy concerns still remain. Previously reported experiments used conventional imaging contrast agents that have a wide size distribution. In this study, we hypothesize that BBB opening characteristics are dependent on bubble diameter. A 25 μl bolus of in-house manufactured, lipid-shelled bubbles with either 1-2 or 4-5 μm diameter ranges was injected intravenously. Pulsed FUS (frequency: 1.5 MHz, peak-negative pressure: 146-607 kPa, duty cycle: 20%, duration: 1-min) was then applied to the left hippocampus of mice (n = 16) in vivo through the intact skin and skull. MRI or fluorescence microscopy was used to determine BBB opening. Contrast-enhanced (Omniscan™; 0.75 mL; molecular weight: 574 Da) MRI (9.4-T) was acquired on multiple days after sonication to determine BBB opening and closing. Fluorescence microscopy was also used to determine the feasibility of delivering large, 3 kDa dextran compounds through the BBB. The BBB opening acoustic pressure threshold for the 4-5μm bubbles was in the 146-304 kPa range while the threshold for the 1-2μm bubbles was higher. In conclusion, FUS-induced BBB opening and closing was shown to be dependent on the bubble diameter indicating the possibility of specifically designing bubbles to enhance this therapeutic application.

Electron Bubbles in Superfluid (3) 3 He-A: Exploring the Quasiparticle-Ion Interaction

NASA Astrophysics Data System (ADS)

Shevtsov, Oleksii; Sauls, J. A.

2017-06-01

When an electron is forced into liquid ^3He, it forms an "electron bubble", a heavy ion with radius, R˜eq 1.5 nm, and mass, M˜eq 100 m_3, where m_3 is the mass of a ^3He atom. These negative ions have proven to be powerful local probes of the physical properties of the host quantum fluid, especially the excitation spectra of the superfluid phases. We recently developed a theory for Bogoliubov quasiparticles scattering off electron bubbles embedded in a chiral superfluid that provides a detailed understanding of the spectrum of Weyl Fermions bound to the negative ion, as well as a theory for the forces on moving electron bubbles in superfluid ^3He-A (Shevtsov and Sauls in Phys Rev B 94:064511, 2016). This theory is shown to provide quantitative agreement with measurements reported by the RIKEN group (Ikegami et al. in Science 341(6141):59, 2013) for the drag force and anomalous Hall effect of moving electron bubbles in superfluid ^3He-A. In this report, we discuss the sensitivity of the forces on the moving ion to the effective interaction between normal-state quasiparticles and the ion. We consider models for the quasiparticle-ion (QP-ion) interaction, including the hard-sphere potential, constrained random-phase-shifts, and interactions with short-range repulsion and intermediate-range attraction. Our results show that the transverse force responsible for the anomalous Hall effect is particularly sensitive to the structure of the QP-ion potential and that strong short-range repulsion, captured by the hard-sphere potential, provides an accurate model for computing the forces acting on the moving electron bubble in superfluid 3He-A.

Advanced subgrid-scale modeling for convection-dominated species transport at fluid interfaces with application to mass transfer from rising bubbles

NASA Astrophysics Data System (ADS)

Weiner, Andre; Bothe, Dieter

2017-10-01

This paper presents a novel subgrid scale (SGS) model for simulating convection-dominated species transport at deformable fluid interfaces. One possible application is the Direct Numerical Simulation (DNS) of mass transfer from rising bubbles. The transport of a dissolving gas along the bubble-liquid interface is determined by two transport phenomena: convection in streamwise direction and diffusion in interface normal direction. The convective transport for technical bubble sizes is several orders of magnitude higher, leading to a thin concentration boundary layer around the bubble. A true DNS, fully resolving hydrodynamic and mass transfer length scales results in infeasible computational costs. Our approach is therefore a DNS of the flow field combined with a SGS model to compute the mass transfer between bubble and liquid. An appropriate model-function is used to compute the numerical fluxes on all cell faces of an interface cell. This allows to predict the mass transfer correctly even if the concentration boundary layer is fully contained in a single cell layer around the interface. We show that the SGS-model reduces the resolution requirements at the interface by a factor of ten and more. The integral flux correction is also applicable to other thin boundary layer problems. Two flow regimes are investigated to validate the model. A semi-analytical solution for creeping flow is used to assess local and global mass transfer quantities. For higher Reynolds numbers ranging from Re = 100 to Re = 460 and Péclet numbers between Pe =104 and Pe = 4 ṡ106 we compare the global Sherwood number against correlations from literature. In terms of accuracy, the predicted mass transfer never deviates more than 4% from the reference values.

Modeling DNA bubble formation at the atomic scale

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beleva, V; Rasmussen, K. O.; Garcia, A. E.

We describe the fluctuations of double stranded DNA molecules using a minimalist Go model over a wide range of temperatures. Minimalist models allow us to describe, at the atomic level, the opening and formation of bubbles in DNA double helices. This model includes all the geometrical constraints in helix melting imposed by the 3D structure of the molecule. The DNA forms melted bubbles within double helices. These bubbles form and break as a function of time. The equilibrium average number of broken base pairs shows a sharp change as a function of T. We observe a temperature profile of sequencemore » dependent bubble formation similar to those measured by Zeng et al. Long nuclei acid molecules melt partially through the formations of bubbles. It is known that CG rich sequences melt at higher temperatures than AT rich sequences. The melting temperature, however, is not solely determined by the CG content, but by the sequence through base stacking and solvent interactions. Recently, models that incorporate the sequence and nonlinear dynamics of DNA double strands have shown that DNA exhibits a very rich dynamics. Recent extensions of the Bishop-Peyrard model show that fluctuations in the DNA structure lead to opening in localized regions, and that these regions in the DNA are associated with transcription initiation sites. 1D and 2D models of DNA may contain enough information about stacking and base pairing interactions, but lack the coupling between twisting, bending and base pair opening imposed by the double helical structure of DNA that all atom models easily describe. However, the complexity of the energy function used in all atom simulations (including solvent, ions, etc) does not allow for the description of DNA folding/unfolding events that occur in the microsecond time scale.« less

Dynamics of Polydisperse Foam-like Emulsion

NASA Astrophysics Data System (ADS)

Hicock, Harry; Feitosa, Klebert

2011-10-01

Foam is a complex fluid whose relaxation properties are associated with the continuous diffusion of gas from small to large bubbles driven by differences in Laplace pressures. We study the dynamics of bubble rearrangements by tracking droplets of a clear, buoyantly neutral emulsion that coarsens like a foam. The droplets are imaged in three dimensions using confocal microscopy. Analysis of the images allows us to measure their positions and radii, and track their evolution in time. We find that the droplet size distribution fits a Weibull distribution characteristics of foam systems. Additionally, we observe that droplets undergo continuous evolution interspersed by occasional large rearrangements in par with local relaxation behavior typical of foams.

Collective organization in aerotactic motion

NASA Astrophysics Data System (ADS)

Mazza, Marco G.

Some bacteria exhibit interesting behavior in the presence of an oxygen concentration. They perform an aerotactic motion along the gradient until they reach their optimal oxygen concentration. But they often organize collectively by forming dense regions, called 'bands', that travel towards the oxygen source. We have developed a model of swimmers with stochastic interaction rules moving in proximity of an air bubble. We perform molecular dynamics simulations and also solve advection-diffusion equations that reproduce the aerotactic behavior of mono-flagellated, facultative anaerobic bacteria. If the oxygen concentration in the system sinks locally below a threshold value, the formation of a migrating aerotactic band toward the bubble can be observed.

Radiation pressure injection in laser-wakefield acceleration

NASA Astrophysics Data System (ADS)

Liu, Y. L.; Kuramitsu, Y.; Isayama, S.; Chen, S. H.

2018-01-01

We investigated the injection of electrons in laser-wakefield acceleration induced by a self-modulated laser pulse by a two dimensional particle-in-cell simulation. The localized electric fields and magnetic fields are excited by the counter-streaming flows on the surface of the ion bubble, owing to the Weibel or two stream like instability. The electrons are injected into the ion bubble from the sides of it and then accelerated by the wakefield. Contrary to the conventional wave breaking model, the injection of monoenergetic electrons are mainly caused by the electromagnetic process. A simple model was proposed to address the instability, and the growth rate was verified numerically and theoretically.

Investigating the explosivity of shallow sub-aqueous basaltic eruptions

NASA Astrophysics Data System (ADS)

Murtagh, R.; White, J. D. L.

2009-04-01

Volcanic eruptions produce pyroclasts containing vesicles, clearly implying exsolution of volatiles from the magma has occurred. Our aim is to understand the textural characteristics of vesiculated clasts as a quantitative indicator of the eruptive behaviour of a volcano. Assessing water's role in volatile degassing and outgassing has been and is being well documented for terrestrial eruptions; the same cannot be said, however, for their shallow subaqueous counterparts. The eruptive behaviour of Surtseyan volcanoes, which include both subaqueous and subaerial phases (for example, the type-location Surtsey, Iceland in 1963) is under investigation here and for good reason. Volcanic eruptions during which water and basaltic magma come into contact appear to ignite violent eruptions of many of the small "monogenetic" volcanoes so abundant on Earth. A key problem remains that detailed conditions of water-magma interactions are not yet fully understood. Field samples obtained from exposed sequences deposited originally in a subaqueous environment allow for the necessary analysis of lapilli. With the aid of experimental data, mathematical modelling and terrestrial analogues the ambition is to unravel volatile degassing, ascent histories and fragmentation processes, allowing us ultimately to identify both the role water plays in the explosivity of shallow subaqueous eruptions, and the rise history of magma to the point of interaction. The first site, Pahvant Butte is located in southwest Utah, U.S. It is a well preserved tuff cone overlying a subaqueously deposited mound of glassy ash composed of sideromelane and tachylite. It was erupted under ~85m of water into Lake Bonneville approximately 15,300 years ago. Our focus is on samples collected from a well-bedded, broadly scoured coarse ash and lapilli lithofacies on the eastern flank of the edifice. Vesicularity indices span from 52.6% - 60.8%, with very broad vesicularity ranges, 20.6% - 81.0% for one extreme sample. The diverse nature of the vesicularity is reflected also in SEM images. Dense clasts display textures with isolated, tiny, serrate-edged bubbles, while mean- and high-vesicularity clasts display more numerous, medium-sized, rounded bubbles. Based on these observations, fragmentation at various stages of a complex vesiculation history is suggested. The second site, Black Point, is situated in eastern California, U.S. Another emergent volcano, it was erupted into Lake Russell ~13,000 years ago. Similar to Pahvant Butte, its unconsolidated mound consists of glassy ash and lapilli and is topped by indurated, palagonitized tuff ring/cone deposits. A well exposed quarry section on the southeast slopes of the edifice is considered here. Sub-horizontal beds display pinch and swell structures and some cross-stratification. Vesicularity indices extend from 58.7% - 66.6% while vesicularity ranges are broad, 27.8% - 79.7% for example. The higher overall vesicularity implies higher rates of ascent and eruption discharge, a conclusion supported by textural features of bubbles in this section such as a population of uniformly sized small vesicles. Bubble nucleation and growth in an ascending parcel of magma is controlled both by decompression and diffusion of oversaturated volatiles as the magma rises. Bubble growth plays a major role in controlling eruption behaviour and we can obtain useful quantitative records of vesicle size data through thin section imaging and analysis. Vesicle size data can be expressed as number per area (NA), number per volume (NV), cumulative number density (N(>L)), volume fraction, cumulative volume fraction and vesicle size distribution (VSD). Not only can the trends and patterns of bubble size reveal insights into eruptive styles, intensity; bubble nucleation, growth, coalescence and deformation, they can also be analysed with other information to infer volatile content and degassing record. High vesicle number densities have been interpreted as being the result of rapid bubble nucleation at high supersaturations. Homogenous bubble nucleation is symptomatic of large supersaturations and high decompression values, whereas heterogeneous bubble nucleation on pre-existing microlites may occur at much lower saturation and decompression values. The spatial density of bubble nuclei controls the rate of diffusion-limited bubble growth and growth of volatile depletion shells around bubbles. Results thus far are restricted to the Pahvant Butte sample suite and indicate low bubble number densities, which could be reflecting a high connectivity of bubbles; polymodal volume fraction distributions, indicating bubble coalescence and multiple stages of bubble nucleation; VSD plots display curved trends further supporting the theory that bubble coalescence and other ripening processes have occurred. These vesicle-population characteristics are most similar to those reported from Stromboli. Despite this similarity, eruption style, energetics and dispersal are unique to subaqueous eruptions, and are inferred to be equivalent to those that formed the subaqueous base of Surtsey volcano.

Heterogeneous UO2 fuel irradiated up to a high burn-up: Investigation of the HBS and of fission product releases

NASA Astrophysics Data System (ADS)

Noirot, J.; Lamontagne, J.; Nakae, N.; Kitagawa, T.; Kosaka, Y.; Tverberg, T.

2013-11-01

A UO2 fuel with a heterogeneous distribution of 235U was irradiated up to a high burn-up in the Halden Boiling Water Reactor (HBWR). The last 100 days of irradiation were performed with an increased level of linear power. The effect of the heterogeneous fissile isotope distribution on the formation of the HBS was studied free of the possible influence of Pu which exists in heterogeneous MOX fuels. The HBS formed in 235U-rich agglomerates and its main characteristics were very similar to those of the HBS formed in Pu-rich agglomerates of heterogeneous MOX fuels. The maximum local contents of Nd and Xe before HBS formation were studied in this fuel. In addition to a Pu effect that promotes the HBS phenomenon, comparison with previous results for heterogeneous MOX fuels showed that the local fission product concentration was not the only parameter that has to be taken into consideration. It appears that the local actinide depletion by fission and/or the energy locally deposited through electronic interactions in the fission fragment recoils also have an effect on the HBS formation threshold. Moreover, a major release of fission gases from the peripheral 235U-rich agglomerates of HBS bubbles and a Cs radial movement are also evidenced in this heterogeneous UO2. Cs deposits on the peripheral grain boundaries, including the HBS grain boundaries, are considered to reveal the release paths. SUP>235U-rich agglomerates, SUP>235U-poor areas, an intermediate phase with intermediate 235U concentrations. Short fuel rods were fabricated with these pellets. The main characteristics of these fuel rods are shown in Table 1.These rods were irradiated to high burn-ups in the IFA-609/626 of the HBWR and then one was irradiated in the IFA-702 for 100 days. Fig. 2 shows the irradiation history of this fuel. The final average burn-up of the rod was 69 GWd/tU. Due to the flux differences along the rod, however, the average burn-up of the cross section examined was 63 GWd/tU. This fuel experienced high linear powers during the first year of irradiation, but at the end of the IFA-609/626 period, the average linear power of the rod was around 12 kW/m. In the IFA-702, the power was gradually increased over 7 days from 12 kW/m to 22.5 kW/m before it was decreased again to reach ˜19 kW/m at the end of the 100 days forming this part of the irradiation. A LEICA (DM RXA2) optical microscope. A shielded electronic microprobe (EPMA) SX-100R by CAMECA. A shielded scanning electron microscope (SEM): the Philips XL30. Image acquisitions were performed using the ADDA "SIS" system with the AnalySIS software for image analysis. A shielded secondary ion mass spectrometer (SIMS): the CAMECA IMS 6f was capable of analysing the same samples as the SEM and EPMA [16-22]. In the central part of the pellet for all three phases, Xe precipitated into bubbles with very little Xe remaining outside the bubbles. Some Xe-filled bubbles were detected under the surface in this area. They appear as bright spots. Around mid-radius on the periphery of the 235U-poor areas and in the intermediate phase, Xe was depleted on the periphery of the grains. This depletion was not associated with Xe-filled bubbles that would be detected under the polished surface. Moreover, no large intergranular open bubbles were visible. Therefore, this missing gas must have been released. In the 235U-rich agglomerates all over the section, Xe precipitated into bubbles with very little Xe remaining outside the bubbles. The Xe quantitative analyses through 235U-rich agglomerates on the pellet periphery (Fig. 9) confirmed the low quantity of Xe remaining outside the bubbles. This Xe content was around 0.1 wt%. Fig. 10 shows the Xe and Nd EPMA quantitative measurements along a radius of the cross section. In this figure and in Fig. 9, the weight percentage scales were set so that the two profiles would be almost identical without Xe release or precipitation. Along the Xe axis, the Nd profile can be considered as the local Xe production. Fig. 10 shows that the Xe measurement all through the central part is low except for a few points corresponding to unopened but close to the polished surface and detected by EPMA. These points correspond to the bright spots detected in the central part in Fig. 8. High concentrations were detected locally all over the radius on the Nd profile. They correspond to the 235U-rich agglomerates or their surroundings. Outside the central part, these high Nd concentrations correspond to low Xe concentrations, consistent with the maps in Fig. 8 and the detailed analyses across large 235U-rich agglomerates (Fig. 9).Fig. 11 shows a set of Xe (wt%) and (145Nd + 146Nd)/heavy metal radial profiles both acquired by SIMS. Three profiles are show for each set: one in the 235U-rich agglomerates, one in the 235U-poor areas and one in the intermediate phase. The three phases are not homogeneous themselves. This induces differences between (145Nd + 146Nd)/HM SIMS measurement points of a given phase. The (145Nd + 146Nd)/HM results are a reference for the Xe measurements, giving an estimation of the relative Xe local production. The (145Nd + 146Nd)/HM was high in the 235U-rich agglomerates, lower in the intermediate phase and even lower in the 235U-poor areas. Differences similar to those obtained herein between the phases would have been found in the Xe measurements if no release had occurred in any of those phases. The Xe (wt%) results show that this is not the case. The Xe measurements were quite similar in the intermediate phase and in the 235U-poor areas; they would have been higher in the intermediate phase if no release had occurred. The Xe measurements in the 235U-rich agglomerates were very low and lower than in the two other phases. For the 235U-rich agglomerates, there was a very big difference, across the entire radius, between the Xe measured and the Xe local production.In the SIMS Xe measurements, local depth profiles show peaks on a base line [19]. The base line corresponds to the solid solution Xe and to the nano-bubbles. The peaks correspond to Xe in larger bubbles opened by ion beam fuel sputtering. The SIMS total values correspond to the Xe outside these bubbles plus the Xe trapped in these bubbles.Fig. 12 shows the total Xe SIMS results (already shown in Fig. 11) together with the base line measurements for each measurement point and in separate graphs for each phase. The Xe EPMA quantitative measurements used as a background for these three graphs are the same as those in Fig. 10 and are the same for the three graphs, without any phase distinction. The SIMS Xe relative measurements were calibrated through a correspondence between the SIMS base line results and the EPMA measurements [20]. As expected, the SIMS base line profile was consistent with the EPMA all along the profile for each corresponding phase. For example, the SIMS base line in the 235U-rich agglomerates corresponds to the low EPMA measurement points of the Xe in this zone, i.e. the points of the EPMA profile in the 235U-rich agglomerates. By way of comparison between the Xe and the Nd measurements (the latter being rescaled to be representative of the creation level of Xe), Fig. 11 made it possible to identify two main parts on the Xe SIMS radius: The central part 0R to ˜0.5R: In the intermediate phase and the 235U-poor areas, the SIMS total was used to identify this part as a release area. The average fraction of gas measured in the bubbles (the ratio between the gas in the bubbles and the total measurement) was between 60% and 90%. The Xe content outside the bubbles was very low. In the 235U-rich agglomerates, the SIMS total represents only a small fraction of the produced Xe, which means that a large fraction of the Xe is released or not detected by SIMS due to the large size of some agglomerate bubbles compared with the volume of the crater analysed. sim;0.5R to ˜1R: The 235U-poor areas are not release areas. The fraction of gas in bubbles measured in these areas remained low, ˜5%. The intermediate phase is a release area with moderate release. The average fraction of gas measured in the bubbles was around 20%. In the 235U-rich agglomerates, the Xe SIMS total was very low. This part is a release area. Sharp transitions between initial microstructure and the HBS, often inside one grain. Increase in the resulting grain size with increasing distance from the pellet periphery. The grain sizes are in fact consistent with the MOX measurements [2]. Increase in the bubble size with the increasing distance from the pellet periphery, consistent with the MOX measurements. Smaller bubbles tend to be found in the peripheral part of the 235U-rich agglomerates rather than in their central part. Sharp transition, around 0.5R, between the peripheral area where the conventional form of HBS forms in the 235U-rich agglomerates and the central part where much larger bubbles form and where the grain size is also clearly larger. Xe concentration of 0.1 wt% outside the bubbles in the HBS areas is consistent with the [2] MOX measurements at equivalent local burn-ups. The heterogeneous MOX fuels examinations have firmly established that the HBS can extend outside the Pu-rich agglomerates due to the implantation of fission products around these agglomerates. Similarly, it has been shown that the small Pu-rich agglomerates can remain with the initial microstructure even if there is a similar actual local burn-up, a large rate of fission products being implanted outside the agglomerates themselves so that the local fission product concentration remains low.In this 235U heterogeneous UO2, the Xe and Nd concentration levels reached at the HBS formation limit ranged between 0.8 wt% and 1.1 wt% for Xe and between 0.63 wt% and 0.83 wt% for Nd. These ranges are similar to what was reported in [23] for the UO2 rim. These limits are, however, slightly higher than those found for Pu-rich agglomerates in heterogeneous MOX fuels in [2] or in [24]. Nonetheless, they are clearly lower than the concentrations reached without HBS in the special Pu-poor spots in [2]. In these spots, UO2 particles in heterogeneous MOX were really close or even surrounded by Pu-rich areas. As a result, their fission product content, due to recoil, was almost the same as that in the surrounding Pu-rich agglomerates themselves despite a very low actual local burn-up. In these special UO2 spots in MOX fuel, 1.4 wt% was reached for Xe and no HBS formed.If these high Xe concentrations without HBS in the special spots in [2] were made possible by the very low Pu local concentration only, very high Xe concentrations should have been common around the heterogeneous UO2 fuel 235U-rich agglomerates, since the Pu level was low everywhere in this fuel. This is not what was observed.Even if this effect due to a high fission product level reached without the formation of a HBS (as reported in [2] for heterogeneous MOX fuels in the special spots) is partially due to the very low local Pu level, it does not seem to be the only reason. It also seems to be partly due to the very low level of actual fissions occurring there. Between a rich agglomerate and such a highly implanted area there is: The same local fission product build-up and associated damage (due to cascades from the nuclei interactions during the last part of the fission fragment recoil). A large difference in the actinide isotope depletion to the extent that a difference in chemical composition exists between the two. A difference in the electronic excitation level at the beginning of the fission fragment recoil, higher in Pu agglomerates and in 235U-rich agglomerates than in the low fissile content areas, even surrounded by rich areas. The last two points may have an effect on the formation of a HBS though this paper cannot say which one is the most significant.The highest levels reached for Xe and Nd without HBS in the 235U heterogeneous fuel are very likely to correspond to places where the initial 235U content was particularly low but where fission recoil led to these high levels. The maximum concentrations of fission products reached before the formation of a HBS in the 235U heterogeneous fuel are lower than for the heterogeneous MOX special Pu-poor spots. This is most certainly due to the local 235U initial concentration in the 235U-poor areas which is nonetheless high when compared with the initial Pu concentrations in the Pu-poor areas in the MOX fuel. Consequently, there are more fission reactions there in the heterogeneous UO2 fuel than in the MOX fuel.This fission and/or fission spike effect has in fact little impact on the overall fuel behaviour, be it homogeneous or heterogeneous, but it has to be taken into account in the separate-effect experiments where unirradiated UO2 is submitted to ion irradiation to simulate the irradiation effects [9,25-30]. The depletion of the actinide isotopes cannot be simulated in these experiments. The IFA-702 re-irradiation, with the high power during the last period of the irradiation most certainly having played a role. The other major difference between this fuel was irradiated under BWR conditions, whereas those used in [2] were all PWR fuels. The images of the IFA-702 heterogeneous UO2 fuel on the periphery show that an internal zirconia layer was formed during the irradiation, which is a sign of gap closure under hot conditions, though a thin gap was still measured at room temperature. Therefore, the stress field in the pellet of this fuel must have been significantly different from that of the fuel used in [2]. The resulting release is all the more interesting since the release path is more or less revealed by the Cs deposits. This Cs is released from the hot central part of the pellet and is not only in the fuel-cladding gap and along the obvious radial cracks, but also in: All the grain boundaries around those radial cracks. The HBS 235U-rich agglomerates around those radial cracks. Like for Xe, the general trend for Cs was a release from the 235U peripheral agglomerates. The higher Cs measurement in the 235U-rich agglomerates close to the radial cracks results from both this release and the deposition of the Cs released from the hot central part.This singular release of Xe from the HBS bubbles of the 235U-rich agglomerates on the fuel periphery is all the more surprising that the Pu-rich agglomerates of the MIMAS MOX fuel irradiated under the same conditions [15] retained their fission gases in these areas. We found no definitive reason for that difference. the fission product implantation level has an effect. the local Pu content has also an effect. the actual local burn-up has an effect. This effect may be linked to fission through the local depletion of the fissile isotopes which changes the local chemical composition, as well as to the higher energy deposited there by electronic interactions at the beginning of the fission fragment recoils when compared with implanted areas with a low actual burn-up. Moreover, the major release of fission gases from the peripheral 235U-rich agglomerate HBS bubbles was evidenced in this heterogeneous UO2 fuel.The radial movement of Cs from the central part of the pellet towards its periphery was shown. This involved a deposition at the grain boundaries, including the HBS ones, around the radial cracks in the periphery. This showed the intergranular paths existing for the release of fission gases and Cs all through the fuel periphery. Grain Equivalent Circular Diameter (ECD) for which half of the surface is made of smaller grains and half of larger grains

On The Origin Of Two-Shell Supernova Remnants

NASA Astrophysics Data System (ADS)

Gvaramadze, V. V.

2006-08-01

It is known that proper motion of massive stars causes them to explode far from the geometric centers of their wind-driven bubbles and thereby affects the symmetry of the resulting diffuse supernova remnants (SNRs). We use this fact to explain the origin of SNRs consisting of two partially overlapping shells (e.g. 3C 400.2, Cygnus Loop, Kes32, etc.), whose unusual morphology is usually treated in terms of the collision (or superposition) of two separate SNRs or breakout phenomena in a region with a density discontinuity. We propose that a SNR of this type is a natural consequence of an off-centered cavity supernova (SN) explosion of a moving massive star, which ended its evolution near the edge of the main-sequence (MS) wind-driven bubble. Our proposal implies that one of the shells is the former MS bubble reenergized by the SN blast wave. The second shell, however, could originate in two somewhat different ways, depending on the initial mass of the SN progenitor star. It could be a shell swept-up by the SN blast wave expanding through the unperturbed ambient interstellar medium if the massive star ends its evolution as a red supergiant (RSG). Or it could be the remainder of a pre-existing shell (adjacent to the MS bubble) swept-up by the fast progenitor's wind during the late evolutionary phases if after the RSG phase the star evolves through the Wolf-Rayet phase. In both cases the resulting (two-shell) SNR should be associated only with one (young) neutron star (thus one can somewhat improve the statistics of neutron star/SNR associations since the two-shell SNRs are quite numerous). We discuss several criteria to discern the SNRs formed by SN explosion after the RSG or WR phase.

Optimization of MBR hydrodynamics for cake layer fouling control through CFD simulation and RSM design.

PubMed

Yang, Min; Yu, Dawei; Liu, Mengmeng; Zheng, Libing; Zheng, Xiang; Wei, Yuansong; Wang, Fang; Fan, Yaobo

2017-03-01

Membrane fouling is an important issue for membrane bioreactor (MBR) operation. This paper aims at the investigation and the controlling of reversible membrane fouling due to cake layer formation and foulants deposition by optimizing MBR hydrodynamics through the combination of computational fluid dynamics (CFD) and design of experiment (DOE). The model was validated by comparing simulations with measurements of liquid velocity and dissolved oxygen (DO) concentration in a lab-scale submerged MBR. The results demonstrated that the sludge concentration is the most influencing for responses including shear stress, particle deposition propensity (PDP), sludge viscosity and strain rate. A medium sludge concentration of 8820mgL -1 is optimal for the reduction of reversible fouling in this submerged MBR. The bubble diameter is more decisive than air flowrate for membrane shear stress due to its role in sludge viscosity. The optimal bubble diameter was at around 4.8mm for both of shear stress and PDP. Copyright © 2016 Elsevier Ltd. All rights reserved.

Dynamics of Rear Stagnant Cap formation at the surface of spherical bubbles rising in surfactant solutions at large Reynolds numbers under conditions of small Marangoni number and slow sorption kinetics.

PubMed

Dukhin, S S; Kovalchuk, V I; Gochev, G G; Lotfi, M; Krzan, M; Malysa, K; Miller, R

2015-08-01

On the surface of bubbles rising in a surfactant solution the adsorption process proceeds and leads to the formation of a so called Rear Stagnant Cap (RSC). The larger this RSC is the stronger is the retardation of the rising velocity. The theory of a steady RSC and steady retarded rising velocity, which sets in after a transient stage, has been generally accepted. However, a non-steady process of bubble rising starting from the initial zero velocity represents an important portion of the trajectory of rising, characterized by a local velocity profile (LVP). As there is no theory of RSC growth for large Reynolds numbers Re » 1 so far, the interpretation of LVPs measured in this regime was impossible. It turned out, that an analytical theory for a quasi-steady growth of RSC is possible for small Marangoni numbers Ma « 1, i.e. when the RSC is almost completely compressed, which means a uniform surface concentration Γ(θ)=Γ(∞) within the RSC. Hence, the RSC angle ψ(t) is obtained as a function of the adsorption isotherm parameters and time t. From the steady velocity v(st)(ψ), the dependence of non-steady velocity on time is obtained by employing v(st)[ψ(t)] via a quasi-steady approximation. The measurement of LVP creates a promising new opportunity for investigation of the RSC dynamics and adsorption kinetics. While adsorption and desorption happen at the same localization in the classical methods, in rising bubble experiments desorption occurs mainly within RSC while adsorption on the mobile part of the bubble surface. The desorption flux from RSC is proportional to αΓ(∞), while it is usually αΓ. The adsorption flux at the mobile surface above RSC can be assumed proportional to βC0, while it is usually βC0(1-Γ/Γ(∞)). These simplifications may become favorable in investigations of the adsorption kinetics for larger molecules, in particular for globular proteins, which essentially stay at an interface once adsorbed. Copyright © 2014 Elsevier B.V. All rights reserved.

Fundamental study of FC-72 pool boiling surface temperature fluctuations and bubble behavior

NASA Astrophysics Data System (ADS)

Griffin, Alison R.

A heater designed to monitor surface temperature fluctuations during pool boiling experiments while the bubbles were simultaneously being observed has been fabricated and tested. The heat source was a transparent indium tin oxide (ITO) layer commercially deposited on a fused quartz substrate. Four copper-nickel thin film thermocouples (TFTCs) on the heater surface measured the surface temperature, while a thin layer of sapphire or fused silica provided electrical insulation between the TFTCs and the ITO. The TFTCs were micro-fabricated using the liftoff process to deposit the nickel and copper metal films. The TFTC elements were 50 mum wide and overlapped to form a 25 mum by 25 mum junction. TFTC voltages were recorded by a DAQ at a sampling rate of 50 kHz. A high-speed CCD camera recorded bubble images from below the heater at 2000 frames/second. A trigger sent to the camera by the DAQ synchronized the bubble images and the surface temperature data. As the bubbles and their contact rings grew over the TFTC junction, correlations between bubble behavior and surface temperature changes were demonstrated. On the heaters with fused silica insulation layers, 1--2°C temperature drops on the order of 1 ms occurred as the contact ring moved over the TFTC junction during bubble growth and as the contact ring moved back over the TFTC junction during bubble departure. These temperature drops during bubble growth and departure were due to microlayer evaporation and liquid rewetting the heated surface, respectively. Microlayer evaporation was not distinguished as the primary method of heat removal from the surface. Heaters with sapphire insulation layers did not display the measurable temperature drops observed with the fused silica heaters. The large thermal diffusivity of the sapphire compared to the fused silica was determined as the reason for the absence of these temperature drops. These findings were confirmed by a comparison of temperature drops in a 2-D simulation of a bubble growing over the TFTC junction on both the sapphire and fused silica heater surfaces. When the fused silica heater produced a temperature drop of 1.4°C, the sapphire heater produced a drop of only 0.04°C under the same conditions. These results verified that the lack of temperature drops present in the sapphire data was due to the thermal properties of the sapphire layer. By observing the bubble departure frequency and site density on the heater, as well as the bubble departure diameter, the contribution of nucleate boiling to the overall heat removal from the surface could be calculated. These results showed that bubble vapor generation contributed to approximately 10% at 1 W/cm2, 23% at 1.75 W/cm2, and 35% at 2.9 W/cm 2 of the heat removed from a fused silica heater. Bubble growth and contact ring growth were observed and measured from images obtained with the high-speed camera. Bubble data recorded on a fused silica heater at 3 W/cm2, 4 W/cm2, and 5 W/cm 2 showed that bubble departure diameter and lifetime were negligibly affected by the increase in heat flux. Bubble and contact ring growth rates demonstrated significant differences when compared on the fused silica and sapphire heaters at 3 W/cm2. The bubble departure diameters were smaller, the bubble lifetimes were longer, and the bubble departure frequency was larger on the sapphire heater, while microlayer evaporation was faster on the fused silica heater. Additional considerations revealed that these differences may be due to surface conditions as well as differing thermal properties. Nucleate boiling curves were recorded on the fused silica and sapphire heaters by adjusting the heat flux input and monitoring the local surface temperature with the TFTCs. The resulting curves showed a temperature drop at the onset of nucleate boiling due to the increase in heat transfer coefficient associated with bubble nucleation. One of the TFTC locations on the sapphire heater frequently experienced a second temperature drop at a higher heat flux. When the heat flux was started from 1 W/cm2 instead of zero or returned to zero only momentarily, the temperature overshoot did not occur. In these cases sufficient vapor remained in the cavities to initiate boiling at a lower superheat.

Stimulus features coded by single neurons of a macaque body category selective patch.

PubMed

Popivanov, Ivo D; Schyns, Philippe G; Vogels, Rufin

2016-04-26

Body category-selective regions of the primate temporal cortex respond to images of bodies, but it is unclear which fragments of such images drive single neurons' responses in these regions. Here we applied the Bubbles technique to the responses of single macaque middle superior temporal sulcus (midSTS) body patch neurons to reveal the image fragments the neurons respond to. We found that local image fragments such as extremities (limbs), curved boundaries, and parts of the torso drove the large majority of neurons. Bubbles revealed the whole body in only a few neurons. Neurons coded the features in a manner that was tolerant to translation and scale changes. Most image fragments were excitatory but for a few neurons both inhibitory and excitatory fragments (opponent coding) were present in the same image. The fragments we reveal here in the body patch with Bubbles differ from those suggested in previous studies of face-selective neurons in face patches. Together, our data indicate that the majority of body patch neurons respond to local image fragments that occur frequently, but not exclusively, in bodies, with a coding that is tolerant to translation and scale. Overall, the data suggest that the body category selectivity of the midSTS body patch depends more on the feature statistics of bodies (e.g., extensions occur more frequently in bodies) than on semantics (bodies as an abstract category).

Stimulus features coded by single neurons of a macaque body category selective patch

PubMed Central

Popivanov, Ivo D.; Schyns, Philippe G.; Vogels, Rufin

2016-01-01

Body category-selective regions of the primate temporal cortex respond to images of bodies, but it is unclear which fragments of such images drive single neurons’ responses in these regions. Here we applied the Bubbles technique to the responses of single macaque middle superior temporal sulcus (midSTS) body patch neurons to reveal the image fragments the neurons respond to. We found that local image fragments such as extremities (limbs), curved boundaries, and parts of the torso drove the large majority of neurons. Bubbles revealed the whole body in only a few neurons. Neurons coded the features in a manner that was tolerant to translation and scale changes. Most image fragments were excitatory but for a few neurons both inhibitory and excitatory fragments (opponent coding) were present in the same image. The fragments we reveal here in the body patch with Bubbles differ from those suggested in previous studies of face-selective neurons in face patches. Together, our data indicate that the majority of body patch neurons respond to local image fragments that occur frequently, but not exclusively, in bodies, with a coding that is tolerant to translation and scale. Overall, the data suggest that the body category selectivity of the midSTS body patch depends more on the feature statistics of bodies (e.g., extensions occur more frequently in bodies) than on semantics (bodies as an abstract category). PMID:27071095

Physics of puffing and microexplosion of emulsion fuel droplets

NASA Astrophysics Data System (ADS)

Shinjo, J.; Xia, J.; Ganippa, L. C.; Megaritis, A.

2014-10-01

The physics of water-in-oil emulsion droplet microexplosion/puffing has been investigated using high-fidelity interface-capturing simulation. Varying the dispersed-phase (water) sub-droplet size/location and the initiation location of explosive boiling (bubble formation), the droplet breakup processes have been well revealed. The bubble growth leads to local and partial breakup of the parent oil droplet, i.e., puffing. The water sub-droplet size and location determine the after-puffing dynamics. The boiling surface of the water sub-droplet is unstable and evolves further. Finally, the sub-droplet is wrapped by boiled water vapor and detaches itself from the parent oil droplet. When the water sub-droplet is small, the detachment is quick, and the oil droplet breakup is limited. When it is large and initially located toward the parent droplet center, the droplet breakup is more extensive. For microexplosion triggered by the simultaneous growth of multiple separate bubbles, each explosion is local and independent initially, but their mutual interactions occur at a later stage. The degree of breakup can be larger due to interactions among multiple explosions. These findings suggest that controlling microexplosion/puffing is possible in a fuel spray, if the emulsion-fuel blend and the ambient flow conditions such as heating are properly designed. The current study also gives us an insight into modeling the puffing and microexplosion of emulsion droplets and sprays.

Experimental studying of local characteristics of gas-liquid flow in microchannels by optical methods

NASA Astrophysics Data System (ADS)

Bartkus, German V.; Kuznetsov, Vladimir V.

2018-03-01

The local characteristics of the gas-liquid two-phase flow in rectangular microchannels 420 × 280 μm and 395 × 205 μm with T-shaped mixer inlet were experimentally investigated in this work. Visualization of flow regimes and measurement of local characteristics were carried out using a high-speed video camera Optronis CX600x2 and laser-induced fluorescence (LIF) method. Deionized water and ethanol were used as the liquid phase, and nitrogen - as the gas phase. The Rhodamine 6G dye was added to the liquid. The location of the microchannel in space (horizontal, vertical) was changed. The profiles of the liquid film along the long side of the microchannel were obtained, the local film thickness was measured in the channel`s central section for the elongated bubble flow and the transition flow of the deionized water-nitrogen mixture. The unevenness of liquid film thickness at the channel cross-section and along the bubble was experimentally shown. The temporal dynamics of two-phase flow for the ethanol-nitrogen mixture was shown. It was found that most of the liquid flows in the meniscus on the short side of the microchannel for the present gas and liquid flow rates.

The Seismic Velocity In Gas-charged Magma

NASA Astrophysics Data System (ADS)

Sturton, S.; Neuberg, J. W.

2001-12-01

Long-period and hybrid events, seen at the Soufrière Hills Volcano, Montserrat, show dominant low frequency content suggesting the seismic wavefield is formed as a result of interface waves at the boundary between a fluid and a solid medium. This wavefield will depend on the impedance contrast between the two media and therefore the difference in seismic velocity. For a gas-charged magma, increasing pressure with depth reduces the volume of gas exsolved, increasing the seismic velocity with depth in the conduit. The seismic radiation pattern along the conduit can then be modelled. Where single events merge into tremor, gliding lines can sometimes be seen in the spectra and indicate either changes in the seismic parameters with time or varying triggering rates of single events.The differential equation describing the time dependence of bubble growth by diffusion is solved numerically for a stationary magma column undergoing a decompression event. The volume of gas is depth dependent and increases with time as the bubbles grow and expand. It is used to calculate the depth and time dependence of the density, pressure and seismic velocity. The effect of different viscosities associated with different magma types and concentration of water in the melt on the rate of bubble growth is explored. Crystal growth, which increases the concentration of water in the melt, affects the amount of gas that can be exsolved.

Laser irradiated fluorescent perfluorocarbon microparticles in 2-D and 3-D breast cancer cell models

NASA Astrophysics Data System (ADS)

Niu, Chengcheng; Wang, Long; Wang, Zhigang; Xu, Yan; Hu, Yihe; Peng, Qinghai

2017-03-01

Perfluorocarbon (PFC) droplets were studied as new generation ultrasound contrast agents via acoustic or optical droplet vaporization (ADV or ODV). Little is known about the ODV irradiated vaporization mechanisms of PFC-microparticle complexs and the stability of the new bubbles produced. In this study, fluorescent perfluorohexane (PFH) poly(lactic-co-glycolic acid) (PLGA) particles were used as a model to study the process of particle vaporization and bubble stability following excitation in two-dimensional (2-D) and three-dimensional (3-D) cell models. We observed localization of the fluorescent agent on the microparticle coating material initially and after vaporization under fluorescence microscopy. Furthermore, the stability and growth dynamics of the newly created bubbles were observed for 11 min following vaporization. The particles were co-cultured with 2-D cells to form 3-D spheroids and could be vaporized even when encapsulated within the spheroids via laser irradiation, which provides an effective basis for further work.

Insertion and confinement of hydrophobic metallic powder in water: the bubble-marble effect.

PubMed

Meir, Yehuda; Jerby, Eli

2014-09-01

Metallic powders such as thermite are known as efficient fuels also applicable in oxygen-free environments. However, due to their hydrophobicity, they hardly penetrate into water. This paper presents an effect that enables the insertion and confinement of hydrophobic metallic powders in water, based on encapsulating an air bubble surrounded by a hydrophobic metallic shell. This effect, regarded as an inverse of the known liquid-marble effect, is named here "bubble marble" (BM). The sole BM is demonstrated experimentally as a stable, maneuverable, and controllable soft-solid-like structure, in a slightly deformed hollow spherical shape of ∼1-cm diameter. In addition to experimental and theoretical BM aspects, this paper also demonstrates its potential for underwater applications, such as transportation of solid objects within BM and underwater combustion of thermite BM by localized microwaves. Hence, the BM phenomena may open new possibilities for heat and thrust generation, as well as material processing and mass transfer underwater.

Insertion and confinement of hydrophobic metallic powder in water: The bubble-marble effect

NASA Astrophysics Data System (ADS)

Meir, Yehuda; Jerby, Eli

2014-09-01

Metallic powders such as thermite are known as efficient fuels also applicable in oxygen-free environments. However, due to their hydrophobicity, they hardly penetrate into water. This paper presents an effect that enables the insertion and confinement of hydrophobic metallic powders in water, based on encapsulating an air bubble surrounded by a hydrophobic metallic shell. This effect, regarded as an inverse of the known liquid-marble effect, is named here "bubble marble" (BM). The sole BM is demonstrated experimentally as a stable, maneuverable, and controllable soft-solid-like structure, in a slightly deformed hollow spherical shape of ˜1-cm diameter. In addition to experimental and theoretical BM aspects, this paper also demonstrates its potential for underwater applications, such as transportation of solid objects within BM and underwater combustion of thermite BM by localized microwaves. Hence, the BM phenomena may open new possibilities for heat and thrust generation, as well as material processing and mass transfer underwater.

THE INTERSTELLAR MEDIUM IN THE KEPLER SEARCH VOLUME

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Marshall C.; Redfield, Seth; Jensen, Adam G., E-mail: mjohnson@astro.as.utexas.edu

2015-07-10

The properties of the interstellar medium (ISM) surrounding a planetary system can impact planetary climate through a number of mechanisms, including changing the size of the astrosphere (one of the major shields for cosmic rays) as well as direct deposition of material into planetary atmospheres. In order to constrain the ambient ISM conditions for exoplanetary systems, we present observations of interstellar Na i and K i absorption toward seventeen early type stars in the Kepler prime mission field of view (FOV). We identify 39 Na i and 8 K i velocity components, and attribute these to 11 ISM clouds. Sixmore » of these are detected toward more than one star, and for these clouds we put limits on the cloud properties, including distance and hydrogen number density. We identify one cloud with significant (≳1.5 cm{sup −3}) hydrogen number density located within the nominal ∼100 pc boundary of the Local Bubble. We identify systems with confirmed planets within the Kepler FOV that could lie within these ISM clouds, and estimate upper limits on the astrosphere sizes of these systems under the assumption that they do lie within these clouds. Under this condition, the Kepler-20, 42, and 445 multiplanet systems could have compressed astrospheres much smaller than the present-day heliosphere. Among the known habitable zone planet hosts, Kepler-186 could have an astrosphere somewhat smaller than the heliosphere, while Kepler-437 and KOI-4427 could have astrospheres much larger than the heliosphere. The thick disk star Kepler-444 may have an astrosphere just a few AU in radius.« less

Defining the unknowns of sonoluminescence

NASA Astrophysics Data System (ADS)

Barber, Bradley P.; Hiller, Robert A.; Löfstedt, Ritva; Putterman, Seth J.; Weninger, Keith R.

1997-03-01

As the intensity of a standing sound wave is increased the pulsations of a bubble of gas trapped at a velocity node attain sufficient amplitude so as to emit picosecond flashes of light with a broadband spectrum that increases into the ultraviolet. The acoustic resonator can be tuned so that the flashes of light occur with a clocklike regularity: one flash for each cycle of sound with a jitter in the time between flashes that is also measured in picoseconds. This phenomenon (sonoluminescence or “SL”) is remarkable because it is the only means of generating picosecond flashes of light that does not use a laser and the input acoustic energy density must be concentrated by twelve orders of magnitude in order to produce light. Light scattering measurements indicate that the bubble wall is collapsing at more than 4 times the ambient speed of sound in the gas just prior to the light emitting moment when the gas has been compressed to a density determined by its van der Waals hard core. Experiments indicate that the collapse is remarkably spherical, water is the best fluid for SL, some noble gas is essential for stable SL, and that the light intensity increases as the ambient temperature is lowered. In the extremely stable experimental configuration consisting of an air bubble in water, measurements indicate that the bubble chooses an ambient radius that is not explained by mass diffusion. Experiments have not yet been able to map out the complete spectrum because above 6 eV it is obscured by the cutoff imposed by water, and furthermore experiments have only determined an upper bound on the flash widths. In addition to the above puzzles, the theory for the light emitting mechanism is still open. The scenario of a supersonic bubble collapse launching an imploding shock wave which ionizes the bubble contents so as to cause it to emit Bremsstrahlung radiation is the best candidate theory but it has not been shown how to extract from it the richness of this phenomenon. Most exciting is the issue of whether SL is a classical effect or whether Planck's constant should be invoked to explain how energy which enters a medium at the macroscopic scale holds together and focuses so as to be emitted at the microscopic scale.

Local and global gravitational aspects of domain wall space-times

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cvetic, M.; Griffies, S.; Soleng, H.H.

1993-09-15

Local and global gravitational effects induced by eternal vacuum domain walls are studied. We concentrate on thin walls between nonequal and nonpositive cosmological constants on each side of the wall. The assumption of homogeneity, isotropy, and geodesic completeness of the space-time intrinsic to the wall as described in the comoving coordinate system and the constraint that the same symmetries hold in hypersurfaces parallel to the wall yield a general [ital Ansatz] for the line element of space-time. We restrict the problem further by demanding that the wall's surface energy density, [sigma], is positive and by requiring that the infinitely thinmore » wall represents a thin-wall limit of kinklike scalar field configuration. These vacuum domain walls fall in three classes depending on the value of their [sigma]: (1) extreme walls with [sigma]=[sigma][sub ext] are planar, static walls corresponding to supersymmetric configurations, (2) nonextreme walls with [sigma]=[sigma][sub non][gt][sigma][sub ext] correspond to expanding bubbles with observers on either side of the wall being [ital inside] the bubble, and (3) ultraextreme walls with [sigma]=[sigma][sub ultra][lt][sigma][sub ext] represent the bubbles of false vacuum decay. On the sides with less negative cosmological constant, the extreme, nonextreme, and ultraextreme walls exhibit no, repulsive, and attractive effective gravitational forces,'' respectively. These gravitational forces'' are global effects not caused by local curvature. Since the nonextreme wall encloses observers on both sides, the supersymmetric system has the lowest gravitational mass accessible to outside observers. It is conjectured that similar positive mass protection occurs in all physical systems and that no finite negative mass object can exist inside the universe.« less

Mechanical algal disruption for efficient biodiesel extraction

NASA Astrophysics Data System (ADS)

Krehbiel, Joel David

Biodiesel from algae provides several benefits over current biodiesel feedstocks, but the energy requirements of processing algae into a useable fuel are currently so high as to be prohibitive. One route to improving this is via disruption of the cells prior to lipid extraction, which can significantly increase energy recovery. Unfortunately, several obvious disruption techniques require more energy than can be gained. This dissertation examines the use of microbubbles to improve mechanical disruption of algal cells using experimental, theoretical, and computational methods. New laboratory experiments show that effective ultrasonic disruption of algae is achieved by adding microbubbles to an algal solution. The configuration studied flows the solution through a tube and insonifies a small section with a high-pressure ultrasound wave. Previous biomedical research has shown effective cell membrane damage on animal cells with similar methods, but the present research is the first to extend such study to algal cells. Results indicate that disruption increases with peak negative pressure between 1.90 and 3.07 MPa and with microbubble concentration up to 12.5 x 107 bubbles/ml. Energy estimates of this process suggest that it requires only one-fourth the currently most-efficient laboratory-scale disruption process. Estimates of the radius near each bubble that causes disruption (i.e. the disruption radius) suggest that it increases with peak negative pressure and is near 9--20 microm for all cases tested. It is anticipated that these procedures can be designed for better efficiency and efficacy, which will be facilitated by identifying the root mechanisms of the bubble-induced disruption. We therefore examine whether bubble expansion alone creates sufficient cell deformation for cell rupture. The spherically-symmetric Marmottant model for bubble dynamics allows estimation of the flow regime under experimental conditions. Bubble expansion is modeled as a point source of mass at the bubble center, and if the bubble-to-cell spacing is much larger than the cell radius, the flow around the cell is approximately extensional in the cell's frame of reference. It is known that the present algae are quasi-spherical with cytoplasmic viscosity approximately 100 times that of water, so the cell is approximated as a viscous sphere. Thus, conditions that cause cell disruption from an expanding microbubble are modeled as either steady inviscid extensional flow or steady point source flow over a viscous sphere. In the inviscid extensional flow model, the flow inside the sphere is dominated by viscous forces so the Stokes equation is solved with matched stresses at the sphere surface from the exterior inviscid extensional flow. The short-time deformation of the sphere surface suggests that inviscid extensional flow is insufficient to disrupt cells. This indicates that asymmetry of the flow over the sphere may be required to provide sufficient surface areal strain to rupture the cell. In a more detailed model, the bubble expansion is modeled as an expansion near a viscous sphere using finite element software. For conditions similar to those seen in the experiment, deformation shows similar scaling to disruption. The deformation in this model is significantly higher than predicted from the inviscid extensional flow model due to the effect of asymmetric flow on the cell membrane. Estimates suggest 21% average areal strain on the algal membrane is required to disrupt algal cells, and this result agrees well with areal strains typically required to disrupt cell membranes although the actual value would be lessened by the effect of an elastic membrane, which is neglected in the present model. The local areal strain on the sphere surface is a maximum closest to the point source, and there is compressive strain near theta = +/-pi/4 with theta the angle from the line between the cell center and the point source. The maximum local areal strain shows less sensitivity to the viscosity of the interior fluid than the average areal strain. Overall, the dissertation lays the groundwork for more efficient algal disruption through the judicious use of microbubbles. Separation of bubble generation and bubble growth provides the ability to improve the efficiency of each process and localize energy. Results suggest that effective disruption can occur by pulsing high-pressure ultrasound waves to a solution of cells co-suspended with microbubbles. The models are thought to represent basic phenomenological mechanisms of disruption that could be exploited to improve the overall energy efficiency of schemes. Analysis suggests that extensional flow alone cannot be the cause of cell disruption near an expanding microbubble. Additionally, this work provides an estimate of the areal strain required disrupt an algal cell membrane. This research suggests a couple routes toward reducing the energy required for production of algal biodiesel.

Holographic particle detection

NASA Technical Reports Server (NTRS)

Bowen, Theodore

1988-01-01

The feasibility was studied of developing a novel particle track detector based on the detection of 1p-1s emission radiation from electron bubbles in liquid helium. The principles, design, construction, and initial testing of the detection system have been described in previous reports. The main obstacle encountered was the construction of the liquid-helium tight infrared windows. Despite numerous efforts in testing and redesigning the windows, the problem of window leakage at low temperature persisted. Due to limited time and resources, attention was switched to investigating the possibility of using room-temperature liquid as the detection medium. A possible mechanism was the detection of de-excitation radiation emitted from localized electrons in common liquids where electrons exhibit low mobilities, as suggested in the previous report. The purity of the liquid is critical in this method as the dissolved impurities (such as oxygen), even in trace amounts, will act as scavengers of electrons. Another mechanism is discussed whereby the formation of the superoxide ions by electron scavenging behavior of dissolved oxygen is exploited to detect the track of ionizing particles. An experiment to measure the ionization current produced in a liquid by a pulsed X-ray beam in order to study propertiies of the ions is also reported.

Scanning force microscopy at the air-water interface of an air bubble coated with pulmonary surfactant.

PubMed Central

Knebel, D; Sieber, M; Reichelt, R; Galla, H-J; Amrein, M

2002-01-01

To study the structure-function relationship of pulmonary surfactant under conditions close to nature, molecular films of a model system consisting of dipalmitoylphosphatidylcholine, dipalmitoylphosphatidylglycerol, and surfactant-associated protein C were prepared at the air-water interface of air bubbles about the size of human alveoli (diameter of 100 microm). The high mechanical stability as well as the absence of substantial film flow, inherent to small air bubbles, allowed for scanning force microscopy (SFM) directly at the air-water interface. The SFM topographical structure was correlated to the local distribution of fluorescent-labeled dipalmitoylphosphatidylcholine, as revealed from fluorescence light microscopy of the same bubbles. Although SFM has proven before to be exceptionally well suited to probe the structure of molecular films of pulmonary surfactant, the films so far had to be transferred onto a solid support from the air-water interface of a film balance, where they had been formed. This made them prone to artifacts imposed by the transfer. Moreover, the supported monolayers disallowed the direct observation of the structural dynamics associated with expansion and compression of the films as upon breathing. The current findings are compared in this respect to our earlier findings from films, transferred onto a solid support. PMID:11751334

Gas exchange in the ice zone: the role of small waves and big animals

NASA Astrophysics Data System (ADS)

Loose, B.; Takahashi, A.; Bigdeli, A.

2016-12-01

The balance of air-sea gas exchange and net biological carbon fixation determine the transport and transformation of carbon dioxide and methane in the ocean. Air-sea gas exchange is mostly driven by upper ocean physics, but biology can also play a role. In the open ocean, gas exchange increases proportionate to the square of wind speed. When sea ice is present, this dependence breaks down in part because breaking waves and air bubble entrainment are damped out by interactions between sea ice and the wave field. At the same time, sea ice motions, formation, melt, and even sea ice-associated organisms can act to introduce turbulence and air bubbles into the upper ocean, thereby enhancing air-sea gas exchange. We take advantage of the knowledge advances of upper ocean physics including bubble dynamics to formulate a model for air-sea gas exchange in the sea ice zone. Here, we use the model to examine the role of small-scale waves and diving animals that trap air for insulation, including penguins, seals and polar bears. We compare these processes to existing parameterizations of wave and bubble dynamics in the open ocean, to observe how sea ice both mitigates and locally enhances air-sea gas transfer.

Cavitation clouds created by shock scattering from bubbles during histotripsy

PubMed Central

Maxwell, Adam D.; Wang, Tzu-Yin; Cain, Charles A.; Fowlkes, J. Brian; Sapozhnikov, Oleg A.; Bailey, Michael R.; Xu, Zhen

2011-01-01

Histotripsy is a therapy that focuses short-duration, high-amplitude pulses of ultrasound to incite a localized cavitation cloud that mechanically breaks down tissue. To investigate the mechanism of cloud formation, high-speed photography was used to observe clouds generated during single histotripsy pulses. Pulses of 5−20 cycles duration were applied to a transparent tissue phantom by a 1-MHz spherically focused transducer. Clouds initiated from single cavitation bubbles that formed during the initial cycles of the pulse, and grew along the acoustic axis opposite the propagation direction. Based on these observations, we hypothesized that clouds form as a result of large negative pressure generated by the backscattering of shockwaves from a single bubble. The positive-pressure phase of the wave inverts upon scattering and superimposes on the incident negative-pressure phase to create this negative pressure and cavitation. The process repeats with each cycle of the incident wave, and the bubble cloud elongates toward the transducer. Finite-amplitude propagation distorts the incident wave such that the peak-positive pressure is much greater than the peak-negative pressure, which exaggerates the effect. The hypothesis was tested with two modified incident waves that maintained negative pressure but reduced the positive pressure amplitude. These waves suppressed cloud formation which supported the hypothesis. PMID:21973343

Local ISM 3D Distribution and Soft X-ray Background Inferences for Nearby Hot Gas

NASA Technical Reports Server (NTRS)

Puspitarini, L.; Lallement, R.; Snowden, Steven L.; Vergely, J.-L.; Snowden, S.

2014-01-01

Three-dimensional (3D) interstellar medium (ISM) maps can be used to locate not only interstellar (IS) clouds, but also IS bubbles between the clouds that are blown by stellar winds and supernovae, and are filled by hot gas. To demonstrate this, and to derive a clearer picture of the local ISM, we compare our recent 3D IS dust distribution maps to the ROSAT diffuse Xray background maps after removal of heliospheric emission. In the Galactic plane, there is a good correspondence between the locations and extents of the mapped nearby cavities and the soft (0.25 keV) background emission distribution, showing that most of these nearby cavities contribute to this soft X-ray emission. Assuming a constant dust to gas ratio and homogeneous 106 K hot gas filling the cavities, we modeled in a simple way the 0.25 keV surface brightness along the Galactic plane as seen from the Sun, taking into account the absorption by the mapped clouds. The data-model comparison favors the existence of hot gas in the solar neighborhood, the so-called Local Bubble (LB). The inferred mean pressure in the local cavities is found to be approx.9,400/cu cm K, in agreement with previous studies, providing a validation test for the method. On the other hand, the model overestimates the emission from the huge cavities located in the third quadrant. Using CaII absorption data, we show that the dust to CaII ratio is very small in those regions, implying the presence of a large quantity of lower temperature (non-X-ray emitting) ionized gas and as a consequence a reduction of the volume filled by hot gas, explaining at least part of the discrepancy. In the meridian plane, the two main brightness enhancements coincide well with the LB's most elongated parts and chimneys connecting the LB to the halo, but no particular nearby cavity is found towards the enhancement in the direction of the bright North Polar Spur (NPS) at high latitude. We searched in the 3D maps for the source regions of the higher energy (0.75 keV) enhancements in the fourth and first quadrants. Tunnels and cavities are found to coincide with the main bright areas, however no tunnel nor cavity is found to match the low-latitude b > or approx. 8deg, brightest part of the NPS. In addition, the comparison between the 3D maps and published spectral data favors a NPS central source region location beyond 230 pc, i.e. at larger distance than usually considered. Those examples illustrate the potential use of more detailed 3D distributions of the nearby ISM for the interpretation of the diffuse soft X-ray background.

Efficient generation of cavitation bubbles and reactive oxygen species using triggered high-intensity focused ultrasound sequence for sonodynamic treatment

NASA Astrophysics Data System (ADS)

Yasuda, Jun; Yoshizawa, Shin; Umemura, Shin-ichiro

2016-07-01

Sonodynamic treatment is a method of treating cancer using reactive oxygen species (ROS) generated by cavitation bubbles in collaboration with a sonosensitizer at a target tissue. In this treatment method, both localized ROS generation and ROS generation with high efficiency are important. In this study, a triggered high-intensity focused ultrasound (HIFU) sequence, which consists of a short, extremely high intensity pulse immediately followed by a long, moderate-intensity burst, was employed for the efficient generation of ROS. In experiments, a solution sealed in a chamber was exposed to a triggered HIFU sequence. Then, the distribution of generated ROS was observed by the luminol reaction, and the amount of generated ROS was quantified using KI method. As a result, the localized ROS generation was demonstrated by light emission from the luminol reaction. Moreover, it was demonstrated that the triggered HIFU sequence has higher efficiency of ROS generation by both the KI method and the luminol reaction emission.

Development of an Acoustic Localization Method for Cavitation Experiments in Reverberant Environments

NASA Astrophysics Data System (ADS)

Ranjeva, Minna; Thompson, Lee; Perlitz, Daniel; Bonness, William; Capone, Dean; Elbing, Brian

2011-11-01

Cavitation is a major concern for the US Navy since it can cause ship damage and produce unwanted noise. The ability to precisely locate cavitation onset in laboratory scale experiments is essential for proper design that will minimize this undesired phenomenon. Measuring the cavitation onset is more accurately determined acoustically than visually. However, if other parts of the model begin to cavitate prior to the component of interest the acoustic data is contaminated with spurious noise. Consequently, cavitation onset is widely determined by optically locating the event of interest. The current research effort aims at developing an acoustic localization scheme for reverberant environments such as water tunnels. Currently cavitation bubbles are being induced in a static water tank with a laser, allowing the localization techniques to be refined with the bubble at a known location. The source is located with the use of acoustic data collected with hydrophones and analyzed using signal processing techniques. To verify the accuracy of the acoustic scheme, the events are simultaneously monitored visually with the use of a high speed camera. Once refined testing will be conducted in a water tunnel. This research was sponsored by the Naval Engineering Education Center (NEEC).

Physically-Based Rendering of Particle-Based Fluids with Light Transport Effects

NASA Astrophysics Data System (ADS)

Beddiaf, Ali; Babahenini, Mohamed Chaouki

2018-03-01

Recent interactive rendering approaches aim to efficiently produce images. However, time constraints deeply affect their output accuracy and realism (many light phenomena are poorly or not supported at all). To remedy this issue, in this paper, we propose a physically-based fluid rendering approach. First, while state-of-the-art methods focus on isosurface rendering with only two refractions, our proposal (1) considers the fluid as a heterogeneous participating medium with refractive boundaries, and (2) supports both multiple refractions and scattering. Second, the proposed solution is fully particle-based in the sense that no particles transformation into a grid is required. This interesting feature makes it able to handle many particle types (water, bubble, foam, and sand). On top of that, a medium with different fluids (color, phase function, etc.) can also be rendered.

DESIGN OF CIRCUITS FOR THE PATTERN ARTICULATION UNIT. Report No. 127

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, K.C.

1962-08-31

The Pattern Articulation Unit embodies a central core of 1024 identical processing modules called stalactites'' arranged in a two-dimensional array with only local connectivity. Two possible complete circuit realizations of the stalactite are described. Stalactites of either design contain about 50 transistors, 250 diodes, 250 resistors, and 50 capacitors. Stalactite organization, signal flow, the bubbling register connection, the requirements of a working register, design of stacking logic, mode of operation, circuit design, direct and conditional input, design of bubbling logic, complement circuits, output and circuit, up and down drivers, and cable diivers and terminators are described. Experimental verification of variousmore » components is discussed. (M.C.G.)« less

STUDYING THE INTERSTELLAR MEDIUM AND THE INNER REGION OF NPS/LOOP 1 WITH SHADOW OBSERVATIONS TOWARD MBM36

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ursino, E.; Galeazzi, M.; Liu, W., E-mail: galeazzi@physics.miami.edu

2016-01-01

We analyzed data from a shadow observation of the high density molecular cloud MBM36 (l ∼ 4°, b ∼ 35°) with Suzaku. MBM36 is located in a region that emits relatively weakly in the 3/4 keV band compared to the surrounding North Polar Spur (NPS)/Loop 1 structure and the Galactic Bulge (GB). The contrast between high and low density targets in the MBM36 area allows one to separate the local and distant contributors to the soft diffuse X-ray background, providing a much better characterization of the individual components compared to single pointing observations. We identify two non-local thermal components, one at kT ≈ 0.12 keV andmore » one at kT ≈ 0.29 keV. The colder component matches well with models of emission from the higher latitude region of the GB. The emission of the warmer component is in agreement with models predicting that the NPS is due to a hypershell from the center of the Milky Way. Geometrical and pressure calculations rule out a nearby bubble as responsible for the emission associated with the NPS. Any Galactic Halo/circumgalactic halo emission, if present, is outshined by the other components. We also report an excess emission around 0.9 keV, likely due to an overabundance of Ne ix.« less

TERRESTRIAL EFFECTS OF NEARBY SUPERNOVAE IN THE EARLY PLEISTOCENE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thomas, B. C.; Engler, E. E.; Kachelrieß, M.

Recent results have strongly confirmed that multiple supernovae happened at distances of ∼100 pc, consisting of two main events: one at 1.7–3.2 million years ago, and the other at 6.5–8.7 million years ago. These events are said to be responsible for excavating the Local Bubble in the interstellar medium and depositing {sup 60}Fe on Earth and the Moon. Other events are indicated by effects in the local cosmic ray (CR) spectrum. Given this updated and refined picture, we ask whether such supernovae are expected to have had substantial effects on the terrestrial atmosphere and biota. In a first look atmore » the most probable cases, combining photon and CR effects, we find that a supernova at 100 pc can have only a small effect on terrestrial organisms from visible light and that chemical changes such as ozone depletion are weak. However, tropospheric ionization right down to the ground, due to the penetration of ≥TeV CRs, will increase by nearly an order of magnitude for thousands of years, and irradiation by muons on the ground and in the upper ocean will increase twentyfold, which will approximately triple the overall radiation load on terrestrial organisms. Such irradiation has been linked to possible changes in climate and increased cancer and mutation rates. This may be related to a minor mass extinction around the Pliocene-Pleistocene boundary, and further research on the effects is needed.« less

Terrestrial Effects of Nearby Supernovae in the Early Pleistocene

NASA Astrophysics Data System (ADS)

Thomas, B. C.; Engler, E. E.; Kachelrieß, M.; Melott, A. L.; Overholt, A. C.; Semikoz, D. V.

2016-07-01

Recent results have strongly confirmed that multiple supernovae happened at distances of ˜100 pc, consisting of two main events: one at 1.7-3.2 million years ago, and the other at 6.5-8.7 million years ago. These events are said to be responsible for excavating the Local Bubble in the interstellar medium and depositing 60Fe on Earth and the Moon. Other events are indicated by effects in the local cosmic ray (CR) spectrum. Given this updated and refined picture, we ask whether such supernovae are expected to have had substantial effects on the terrestrial atmosphere and biota. In a first look at the most probable cases, combining photon and CR effects, we find that a supernova at 100 pc can have only a small effect on terrestrial organisms from visible light and that chemical changes such as ozone depletion are weak. However, tropospheric ionization right down to the ground, due to the penetration of ≥TeV CRs, will increase by nearly an order of magnitude for thousands of years, and irradiation by muons on the ground and in the upper ocean will increase twentyfold, which will approximately triple the overall radiation load on terrestrial organisms. Such irradiation has been linked to possible changes in climate and increased cancer and mutation rates. This may be related to a minor mass extinction around the Pliocene-Pleistocene boundary, and further research on the effects is needed.

Structure of local interactions in complex financial dynamics

PubMed Central

Jiang, X. F.; Chen, T. T.; Zheng, B.

2014-01-01

With the network methods and random matrix theory, we investigate the interaction structure of communities in financial markets. In particular, based on the random matrix decomposition, we clarify that the local interactions between the business sectors (subsectors) are mainly contained in the sector mode. In the sector mode, the average correlation inside the sectors is positive, while that between the sectors is negative. Further, we explore the time evolution of the interaction structure of the business sectors, and observe that the local interaction structure changes dramatically during a financial bubble or crisis. PMID:24936906

Regulating Ultrasound Cavitation in order to Induce Reproducible Sonoporation

NASA Astrophysics Data System (ADS)

Mestas, J.-L.; Alberti, L.; El Maalouf, J.; Béra, J.-C.; Gilles, B.

2010-03-01

Sonoporation would be linked to cavitation, which generally appears to be a non reproducible and unstationary phenomenon. In order to obtain an acceptable trade-off between cell mortality and transfection, a regulated cavitation generator based on an acoustical cavitation measurement was developed and tested. The medium to be sonicated is placed in a sample tray. This tray is immersed in in degassed water and positioned above the face of a flat ultrasonic transducer (frequency: 445 kHz; intensity range: 0.08-1.09 W/cm2). This technical configuration was admitted to be conducive to standing-wave generation through reflection at the air/medium interface in the well thus enhancing the cavitation phenomenon. Laterally to the transducer, a homemade hydrophone was oriented to receive the acoustical signal from the bubbles. From this spectral signal recorded at intervals of 5 ms, a cavitation index was calculated as the mean of the cavitation spectrum integration in a logarithmic scale, and the excitation power is automatically corrected. The device generates stable and reproducible cavitation level for a wide range of cavitation setpoint from stable cavitation condition up to full-developed inertial cavitation. For the ultrasound intensity range used, the time delay of the response is lower than 200 ms. The cavitation regulation device was evaluated in terms of chemical bubble collapse effect. Hydroxyl radical production was measured on terephthalic acid solutions. In open loop, the results present a great variability whatever the excitation power. On the contrary the closed loop allows a great reproducibility. This device was implemented for study of sonodynamic effect. The regulation provides more reproducible results independent of cell medium and experimental conditions (temperature, pressure). Other applications of this regulated cavitation device concern internalization of different particles (Quantum Dot) molecules (SiRNA) or plasmids (GFP, DsRed) into different types of cells (AT2, RL, LLC…). Preliminary results are presented.

Recent observations of traveling ionospheric disturbances and plasma bubbles using Optical Mesosphere Thermosphere Imagers in Asian and African sectors

NASA Astrophysics Data System (ADS)

Shiokawa, K.; Otsuka, Y.; Tsuchiya, S.; Moral, A. C.; Okoh, D.

2017-12-01

We review recent observational results of medium-scale traveling ionospheric disturbances (MSTIDs) and equatorial plasma bubbles obtained by using airglow imagers and Fabry-Perot interferometers of the Optical Mesosphere Thermosphere Imagers (OMTIs) at Asian and African sectors. The OMTIs contains 20 airglow imagers and 5 Fabry-Perot interferometers (FPIs) at Canada, USA (Alaska), Russia, Finland, Norway, Iceland, Japan, Thailand, Indonesia, Australia, and Nigeria (http://stdb2.isee.nagoya-u.ac.jp/omti/). The 3-dimentional Fast Fourier Transformation of airglow images makes it possible to analyze 16-year airglow images obtained at Shigaraki (34.8N) and Rikubetsu (43.5N), Japan, to obtain phase velocity spectra of gravity waves and MSTIDs. The MSTIDs spectra show clear southwestward preference of propagation and minor northeastward propagation over Japan. We also found clear negative correlation between MSTID power and solar F10.7 flux, indicating that MSTIDs becomes more active during solar quiet time. This fact suggest the control of ionospheric Perkins and E-F coupling instabilities by solar activities. Three TIDs in airglow images over Indonesia, including midnight brightness waves (MBWs), were compared with CHAMP-satellite overpass to investigate neutral density variations in the thermosphere associated with the TIDs. We found clear correspondence in variations between the airglow intensities and neutral densities, suggesting that the observed TIDs over the equatorial region is caused by gravity waves. We also compare average thermospheric temperatures measured by the four FPIs for 3-4 years with the MSIS90E and GAIA models. The comparison shows that GAIA generally shows better fitting than the MSIS90E, but at the equatorial stations, GAIA tends to fail to reproduce the FPI temperature, probably due to ambiguity of location of the midnight temperature maximum. We also made statistics of plasma bubble occurrence using airglow imager and GNSS receiver at Abuja (9.0N), Nigeria near the geomagnetic equator based on 1.6 year observations. The bubble occurrence is high at equinoxes. There are 33 % of events for which bubble detection by airglow image and GNSS ROTI is different. We discuss possible cause of these differences in the presentation.

Using Simple Field Instruments to Monitor for Biological Production of Methane at Gasoline Spill Sites

EPA Science Inventory

When gasoline containing ethanol is spilled to ground water, natural anaerobic biodegradation of the ethanol can produce copious quantities of methane gas, which bubbles out of the ground water and enters the unsaturated zone. Depending on local circumstances, the concentration...

Bubble snap-off and capillary-back pressure during counter-current spontaneous imbibition into model pores.

PubMed

Unsal, Evren; Mason, Geoffrey; Morrow, Norman R; Ruth, Douglas W

2009-04-09

A previous paper (Unsal, E.; Mason, G.; Ruth, D. W.; Morrow, N. R. J. Colloid Interface Sci. 2007, 315, 200-209) reported experiments involving counter-current spontaneous imbibition into a model pore system consisting of a rod in an angled slot covered by a glass plate. Such an arrangement gives two tubes with different cross-sections (both size and shape) with an interconnection through the gap between the rod and the plate. In the previous experiments, the wetting phase advanced in the small tube and nonwetting phase retreated in the large tube. No bubbles were formed. In this paper, we study experimentally and theoretically the formation of bubbles at the open end of the large tube and their subsequent snap-off. Such bubbles reduce the capillary back pressure produced by the larger tube and can thus have an effect on the local rate of imbibition. In the model pore system, the rod was either in contact with the glass, forming two independent tubes, or the rod was spaced from the glass to allow cross-flow between the tubes. For small gaps, there were three distinct menisci. The one with the highest curvature was between the rod and the plate. The next most highly curved was in the smaller tube, and the least highly curved meniscus was in the large tube and this was the tube from which the bubbles developed. The pressure in the dead end of the system was recorded during imbibition. Once the bubble starts to form outside of the tube, the pressure drops rapidly and then steadies. After the bubble snaps off, the pressure rises to almost the initial value and stays essentially constant until the next bubble starts to form. After snap-off, the meniscus in the large tube appears to invade the large tube for some distance. The snap-off is the result of capillary instability; it takes place significantly inside the large tube with flow of wetting phase moving in the angular corners. As imbibition into the small tube progresses, the rate of imbibition decreases and the time taken for each bubble to form increases, slightly increasing the pressure at which snap-off occurs. The snap-off curvature is only about two-thirds of the curvature of a theoretical cylindrical meniscus within the large tube and about 40% of the curvature of the actual meniscus spanning the large tube.

TOPICAL REVIEW: Ultrasound contrast microbubbles in imaging and therapy: physical principles and engineering

NASA Astrophysics Data System (ADS)

Qin, Shengping; Caskey, Charles F.; Ferrara, Katherine W.

2009-03-01

Microbubble contrast agents and the associated imaging systems have developed over the past 25 years, originating with manually-agitated fluids introduced for intra-coronary injection. Over this period, stabilizing shells and low diffusivity gas materials have been incorporated in microbubbles, extending stability in vitro and in vivo. Simultaneously, the interaction of these small gas bubbles with ultrasonic waves has been extensively studied, resulting in models for oscillation and increasingly sophisticated imaging strategies. Early studies recognized that echoes from microbubbles contained frequencies that are multiples of the microbubble resonance frequency. Although individual microbubble contrast agents cannot be resolved—given that their diameter is on the order of microns—nonlinear echoes from these agents are used to map regions of perfused tissue and to estimate the local microvascular flow rate. Such strategies overcome a fundamental limitation of previous ultrasound blood flow strategies; the previous Doppler-based strategies are insensitive to capillary flow. Further, the insonation of resonant bubbles results in interesting physical phenomena that have been widely studied for use in drug and gene delivery. Ultrasound pressure can enhance gas diffusion, rapidly fragment the agent into a set of smaller bubbles or displace the microbubble to a blood vessel wall. Insonation of a microbubble can also produce liquid jets and local shear stress that alter biological membranes and facilitate transport. In this review, we focus on the physical aspects of these agents, exploring microbubble imaging modes, models for microbubble oscillation and the interaction of the microbubble with the endothelium.

Mechanism of T7 RNAP pausing and termination at the T7 concatemer junction: a local change in transcription bubble structure drives a large change in transcription complex architecture.

PubMed

Nayak, Dhananjaya; Siller, Sylvester; Guo, Qing; Sousa, Rui

2008-02-15

The T7RNA polymerase (RNAP) elongation complex (EC) pauses and is destabilized at a unique 8 nucleotide (nt) sequence found at the junction of the head-to-tail concatemers of T7 genomic DNA generated during T7 DNA replication. The paused EC may recruit the T7 DNA processing machinery, which cleaves the concatemerized DNA within this 8 nt concatemer junction (CJ). Pausing of the EC at the CJ involves structural changes in both the RNAP and transcription bubble. However, these structural changes have not been fully defined, nor is it understood how the CJ sequence itself causes the EC to change its structure, to pause, and to become less stable. Here we use solution and RNAP-tethered chemical nucleases to probe the CJ transcript and changes in the EC structure as the polymerase pauses and terminates at the CJ. Together with extensive mutational scanning of regions of the polymerase that are likely to be involved in recognition of the CJ, we are able to develop a description of the events that occur as the EC transcribes through the CJ and subsequently pauses. In this process, a local change in the structure of the transcription bubble drives a large change in the architecture of the EC. This altered EC structure may then serve as the signal that recruits the processing machinery to the CJ.

Ultrasound contrast microbubbles in imaging and therapy: physical principles and engineering

PubMed Central

Qin, Shengping; Caskey, Charles F; Ferrara, Katherine W

2010-01-01

Microbubble contrast agents and the associated imaging systems have developed over the past twenty-five years, originating with manually-agitated fluids introduced for intra-coronary injection. Over this period, stabilizing shells and low diffusivity gas materials have been incorporated in microbubbles, extending stability in vitro and in vivo. Simultaneously, the interaction of these small gas bubbles with ultrasonic waves has been extensively studied, resulting in models for oscillation and increasingly sophisticated imaging strategies. Early studies recognized that echoes from microbubbles contained frequencies that are multiples of the microbubble resonance frequency. Although individual microbubble contrast agents cannot be resolved—given that their diameter is on the order of microns—nonlinear echoes from these agents are used to map regions of perfused tissue and to estimate the local microvascular flow rate. Such strategies overcome a fundamental limitation of previous ultrasound blood flow strategies; the previous Doppler-based strategies are insensitive to capillary flow. Further, the insonation of resonant bubbles results in interesting physical phenomena that have been widely studied for use in drug and gene delivery. Ultrasound pressure can enhance gas diffusion, rapidly fragment the agent into a set of smaller bubbles or displace the microbubble to a blood vessel wall. Insonation of a microbubble can also produce liquid jets and local shear stress that alter biological membranes and facilitate transport. In this review, we focus on the physical aspects of these agents, exploring microbubble imaging modes, models for microbubble oscillation and the interaction of the microbubble with the endothelium. PMID:19229096

The excitation and characteristic frequency of the long-period volcanic event: An approach based on an inhomogeneous autoregressive model of a linear dynamic system

USGS Publications Warehouse

Nakano, M.; Kumagai, H.; Kumazawa, M.; Yamaoka, K.; Chouet, B.A.

1998-01-01

We present a method to quantify the source excitation function and characteristic frequencies of long-period volcanic events. The method is based on an inhomogeneous autoregressive (AR) model of a linear dynamic system, in which the excitation is assumed to be a time-localized function applied at the beginning of the event. The tail of an exponentially decaying harmonic waveform is used to determine the characteristic complex frequencies of the event by the Sompi method. The excitation function is then derived by operating an AR filter constructed from the characteristic frequencies to the entire seismogram of the event, including the inhomogeneous part of the signal. We apply this method to three long-period events at Kusatsu-Shirane Volcano, central Japan, whose waveforms display simple decaying monochromatic oscillations except for the beginning of the events. We recover time-localized excitation functions lasting roughly 1 s at the start of each event and find that the estimated functions are very similar to each other at all the stations of the seismic network for each event. The phases of the characteristic oscillations referred to the estimated excitation function fall within a narrow range for almost all the stations. These results strongly suggest that the excitation and mode of oscillation are both dominated by volumetric change components. Each excitation function starts with a pronounced dilatation consistent with a sudden deflation of the volumetric source which may be interpreted in terms of a choked-flow transport mechanism. The frequency and Q of the characteristic oscillation both display a temporal evolution from event to event. Assuming a crack filled with bubbly water as seismic source for these events, we apply the Van Wijngaarden-Papanicolaou model to estimate the acoustic properties of the bubbly liquid and find that the observed changes in the frequencies and Q are consistently explained by a temporal change in the radii of the bubbles characterizing the bubbly water in the crack.

Frequency and Size of Strombolian Eruptions from the Phonolitic Lava Lake at Erebus Volcano, Antarctica: Insights from Infrasound and Seismic Observations on Bubble Formation and Ascent

NASA Astrophysics Data System (ADS)

Rotman, H. M. M.; Kyle, P. R.; Fee, D.; Curtis, A.

2015-12-01

Erebus, an active intraplate volcano on Ross Island, commonly produces bubble burst Strombolian explosions from a long-lived, convecting phonolitic lava lake. Persistent lava lakes are rare, and provide direct insights into their underlying magmatic system. Erebus phonolite is H2O-poor and contains ~30% anorthoclase megacrysts. At shallow depths lab measurements suggest the magma has viscosities of ~107 Pa s. This has implications for magma and bubble ascent rates through the conduit and into the lava lake. The bulk composition and matrix glass of Erebus ejecta has remained uniform for many thousands of years, but eruptive activity varies on decadal and shorter time scales. Over the last 15 years, increased activity took place in 2005-2007, and more recently in the 2013 austral summer. In the 2014 austral summer, new infrasound sensors were installed ~700 m from the summit crater hosting the lava lake. These sensors, supplemented by the Erebus network seismic stations, recorded >1000 eruptions between 1 January and 7 April 2015, with an average infrasound daily uptime of 9.6 hours. Over the same time period, the CTBT infrasound station IS55, ~25 km from Erebus, detected ~115 of the >1000 locally observed eruptions with amplitude decreases of >100x. An additional ~200 eruptions were recorded during local infrasound downtime. This represents an unusually high level of activity from the Erebus lava lake, and while instrument noise influences the minimum observable amplitude each day, the eruption infrasound amplitudes may vary by ~3 orders of magnitude over the scale of minutes to hours. We use this heightened period of variable activity and associated seismic and acoustic waveforms to examine mechanisms for bubble formation and ascent, such as rise speed dependence and collapsing foam; repose times for the larger eruptions; and possible eruption connections to lava lake cyclicity.

Theory of supercompression of vapor bubbles and nanoscale thermonuclear fusion

NASA Astrophysics Data System (ADS)

Nigmatulin, Robert I.; Akhatov, Iskander Sh.; Topolnikov, Andrey S.; Bolotnova, Raisa Kh.; Vakhitova, Nailya K.; Lahey, Richard T.; Taleyarkhan, Rusi P.

2005-10-01

This paper provides the theoretical basis for energetic vapor bubble implosions induced by a standing acoustic wave. Its primary goal is to describe, explain, and demonstrate the plausibility of the experimental observations by Taleyarkhan et al. [Science 295, 1868 (2002); Phys. Rev. E 69, 036109 (2004)] of thermonuclear fusion for imploding cavitation bubbles in chilled deuterated acetone. A detailed description and analysis of these data, including a resolution of the criticisms that have been raised, together with some preliminary HYDRO code simulations, has been given by Nigmatulin et al. [Vestnik ANRB (Ufa, Russia) 4, 3 (2002); J. Power Energy 218-A, 345 (2004)] and Lahey et al. [Adv. Heat Transfer (to be published)]. In this paper a hydrodynamic shock (i.e., HYDRO) code model of the spherically symmetric motion for a vapor bubble in an acoustically forced liquid is presented. This model describes cavitation bubble cluster growth during the expansion period, followed by a violent implosion during the compression period of the acoustic cycle. There are two stages of the bubble dynamics process. The first, low Mach number stage, comprises almost all the time of the acoustic cycle. During this stage, the radial velocities are much less than the sound speeds in the vapor and liquid, the vapor pressure is very close to uniform, and the liquid is practically incompressible. This process is characterized by the inertia of the liquid, heat conduction, and the evaporation or condensation of the vapor. The second, very short, high Mach number stage is when the radial velocities are the same order, or higher, than the sound speeds in the vapor and liquid. In this stage high temperatures, pressures, and densities of the vapor and liquid take place. The model presented herein has realistic equations of state for the compressible liquid and vapor phases, and accounts for nonequilibrium evaporation/condensation kinetics at the liquid/vapor interface. There are interacting shock waves in both phases, which converge toward and reflect from the center of the bubble, causing dissociation, ionization, and other related plasma physics phenomena during the final stage of bubble collapse. For a vapor bubble in a deuterated organic liquid (e.g., acetone), during the final stage of collapse there is a nanoscale region (diameter ˜100nm) near the center of the bubble in which, for a fraction of a picosecond, the temperatures and densities are extremely high (˜108K and ˜10g/cm3, respectively) such that thermonuclear fusion may take place. To quantify this, the kinetics of the local deuterium/deuterium (D/D) nuclear fusion reactions was used in the HYDRO code to determine the intensity of the fusion reactions. Numerical HYDRO code simulations of the bubble implosion process have been carried out for the experimental conditions used by Taleyarkhan et al. [Science 295, 1868 (2002); Phys. Rev. E 69, 036109 (2004)] at Oak Ridge National Laboratory. The results show good agreement with the experimental data on bubble fusion that was measured in chilled deuterated acetone.

Free Radical Damage and Noise-Induced Hearing Loss: in vivo in situ Sensing

DTIC Science & Technology

2008-07-01

e.g. imploding, locally nucleating bubbles23-26 ), leading to cellular damage? While ROS can kill cells, they are also part of the apoptotic cascade...reverse side. Electrodes are gold on Kaptonill substrates. Reference electrodes (Ir/IrxOy) are electrodeposited from IrC13 solution. Working

Cluster Dynamics Modeling with Bubble Nucleation, Growth and Coalescence

DOE Office of Scientific and Technical Information (OSTI.GOV)

de Almeida, Valmor F.; Blondel, Sophie; Bernholdt, David E.

The topic of this communication pertains to defect formation in irradiated solids such as plasma-facing tungsten submitted to helium implantation in fusion reactor com- ponents, and nuclear fuel (metal and oxides) submitted to volatile ssion product generation in nuclear reactors. The purpose of this progress report is to describe ef- forts towards addressing the prediction of long-time evolution of defects via continuum cluster dynamics simulation. The di culties are twofold. First, realistic, long-time dynamics in reactor conditions leads to a non-dilute di usion regime which is not accommodated by the prevailing dilute, stressless cluster dynamics theory. Second, long-time dynamics callsmore » for a large set of species (ideally an in nite set) to capture all possible emerging defects, and this represents a computational bottleneck. Extensions beyond the dilute limit is a signi cant undertaking since no model has been advanced to extend cluster dynamics to non-dilute, deformable conditions. Here our proposed approach to model the non-dilute limit is to monitor the appearance of a spatially localized void volume fraction in the solid matrix with a bell shape pro le and insert an explicit geometrical bubble onto the support of the bell function. The newly cre- ated internal moving boundary provides the means to account for the interfacial ux of mobile species into the bubble, and the growth of bubbles allows for coalescence phenomena which captures highly non-dilute interactions. We present a preliminary interfacial kinematic model with associated interfacial di usion transport to follow the evolution of the bubble in any number of spatial dimensions and any number of bubbles, which can be further extended to include a deformation theory. Finally we comment on a computational front-tracking method to be used in conjunction with conventional cluster dynamics simulations in the non-dilute model proposed.« less

Release of Dissolved CO2 from Water in Laboratory Porous Media Following Rapid Depressurization

NASA Astrophysics Data System (ADS)

Crews, J. B.; Cooper, C. A.

2011-12-01

A bench-top laboratory study is undertaken to investigate the effects of seismic shocks on brine aquifers into which carbon dioxide has been injected for permanent storage. Long-term storage in deep saline aquifers has been proposed and studied as one of the most viable near-term options for sequestering fossil fuel-derived carbon dioxide from the atmosphere to curb anthropogenic climate change. Upon injection into the subsurface, it is expected that CO2, as either a gas or supercritical fluid, will mix convectively with the formation water. The possibility exists, however, that dissolved CO2 will come out of solution as a result of an earthquake. The effect is similar to that of slamming an unsealed container of carbonated beverage on a table; previously dissolved CO2 precipitates, forms bubbles, and rises due to buoyancy. In this study, we measure the change in gas-phase CO2 concentration as a function of the magnitude of the shock and the initial concentration of CO2. In addition, we investigate and seek to characterize the nucleation and transport of CO2 bubbles in a porous medium after a seismic shock. Experiments are conducted using a Hele-Shaw cell and a CCD camera to quantify the fraction of dissolved CO2 that comes out of solution as a result of a sharp mechanical impulse. The data are used to identify and constrain the conditions under which CO2 comes out of solution and, further, to understand the end-behavior of the precipitated gas-phase CO2 as it moves through or is immobilized in a porous medium.

Chromatically encoded high-speed photography of cavitation bubble dynamics inside inhomogeneous ophthalmic tissue

NASA Astrophysics Data System (ADS)

Tinne, N.; Matthias, B.; Kranert, F.; Wetzel, C.; Krüger, A.; Ripken, T.

2016-03-01

The interaction effect of photodisruption, which is used for dissection of biological tissue with fs-laser pulses, has been intensively studied inside water as prevalent sample medium. In this case, the single effect is highly reproducible and, hence, the method of time-resolved photography is sufficiently applicable. In contrast, the reproducibility significantly decreases analyzing more solid and anisotropic media like biological tissue. Therefore, a high-speed photographic approach is necessary in this case. The presented study introduces a novel technique for high-speed photography based on the principle of chromatic encoding. For illumination of the region of interest within the sample medium, the light paths of up to 12 LEDs with various emission wavelengths are overlaid via optical filters. Here, MOSFET-electronics provide a LED flash with a duration <100 ns; the diodes are externally triggered with a distinct delay for every LED. Furthermore, the different illumination wavelengths are chromatically separated again for detection via camera chip. Thus, the experimental setup enables the generation of a time-sequence of <= 12 images of a single cavitation bubble dynamics. In comparison to conventional time-resolved photography, images in sample media like water and HEMA show the significant advantages of this novel illumination technique. In conclusion, the results of this study are of great importance for the fundamental evaluation of the laser-tissue interaction inside anisotropic biological tissue and for the optimization of the surgical process with high-repetition rate fs-lasers. Additionally, this application is also suitable for the investigation of other microscopic, ultra-fast events in transparent inhomogeneous materials.

An experimental tool to look in a magma chamber

NASA Astrophysics Data System (ADS)

Gonde, C.; Massare, D.; Bureau, H.; Martel, C.; Pichavant, M.; Clocchiatti, R.

2005-12-01

Understanding the physical and geochemical processes occurring in the volcanoes roots is one of the fundamental tasks of research in the experimental petrology community. This requires experimental tools able to create confining conditions appropriate for magma chambers and conduits. However, the characterization of some natural magmatic processes requires more than a blink experimental approach, to be rigorously studied. In some cases, the in situ approach is the only one issue, because it permits the observation of processes (crystallization of mineral phases, bubble growth.) and their kinetic studies. Here we present a powerful tool, a transparent internally heated autoclave. With this apparatus, pressures (up to 0.3 GPa) and temperatures (up to 900°C) appropriate for subvolcanic magma reservoirs can be obtained. Because it is equipped with transparent sapphire windows, either images or movies can be recorded during an experiment. The pressure medium is Argon, and heating is achieved by a W winding placed into the pressure vessel. Pressure and temperature are calibrated using both well known melting points (eg. salts, metals) and phase transitions (AgI), either at room temperature or at medium and high temperatures. During an experiment, the experimental charge is held between two thick windows of diamond, placed in the furnace cylinder. The experimental volume is about 1 mm3. The observation and numeric record are made along the horizontal axis, through the windows. This apparatus is currently used for studies of nucleation and growth of gas bubbles in a silicate melt. The first results will be presented at the meeting.

Pyroclast/snow interactions and thermally driven slurry formation. Part 2: Experiments and theoretical extension to polydisperse tephra

USGS Publications Warehouse

Walder, J.S.

2000-01-01

Erosion of snow by pyroclastic flows and surges presumably involves mechanical scour, but there may be thermally driven phenomena involved as well. To investigate this possibility, layers of hot (up to 400??C), uniformly sized, fine- to medium-grained sand were emplaced vertically onto finely shaved ice ('snow'); thus there was no relative shear motion between sand and snow and no purely mechanical scour. In some cases large vapor bubbles, commonly more than 10 mm across, rose through the sand layer, burst at the surface, and caused complete convective overturn of the sand, which then scoured and mixed with snow and transformed into a slurry. In other cases no bubbling occurred and the sand passively melted its way downward into the snow as a wetting front moved upward into the sand. A continuum of behaviors between these two cases was observed. Vigorous bubbling and convection were generally favored by high temperature, small grain size, and small layer thickness. A physically based theory of heat- and mass transfer at the pyroclast/snow interface, developed in Part 1 of this paper, does a good job of explaining the observations as a manifestation of unstable vapor-driven fluidization. The theory, when extrapolated to the behavior of actual, poorly sorted pyroclastic flow sediments, leads to the prediction that the observed 'thermal-scour' phenomenon should also occur for many real pyroclastic flows passing over snow. 'Thermal scour' is therefore likely to be involved in the generation of lahars.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Li; He, YaLing; Tao, Wen -Quan

The electrode of a vanadium redox flow battery generally is a carbon fibre-based porous medium, in which important physicochemical processes occur. In this work, pore-scale simulations are performed to study complex multiphase flow and reactive transport in the electrode by using the lattice Boltzmann method (LBM). Four hundred fibrous electrodes with different fibre diameters and porosities are reconstructed. Both the permeability and diffusivity of the reconstructed electrodes are predicted and compared with empirical relationships in the literature. Reactive surface area of the electrodes is also evaluated and it is found that existing empirical relationship overestimates the reactive surface under lowermore » porosities. Further, a pore-scale electrochemical reaction model is developed to study the effects of fibre diameter and porosity on electrolyte flow, V II/V III transport, and electrochemical reaction at the electrolyte-fibre surface. Finally, evolution of bubble cluster generated by the side reaction is studied by adopting a LB multiphase flow model. Effects of porosity, fibre diameter, gas saturation and solid surface wettability on average bubble diameter and reduction of reactive surface area due to coverage of bubbles on solid surface are investigated in detail. It is found that gas coverage ratio is always lower than that adopted in the continuum model in the literature. Furthermore, the current pore-scale studies successfully reveal the complex multiphase flow and reactive transport processes in the electrode, and the simulation results can be further upscaled to improve the accuracy of the current continuum-scale models.« less

Combined passive detection and ultrafast active imaging of cavitation events induced by short pulses of high-intensity ultrasound.

PubMed

Gateau, Jérôme; Aubry, Jean-François; Pernot, Mathieu; Fink, Mathias; Tanter, Mickaël

2011-03-01

The activation of natural gas nuclei to induce larger bubbles is possible using short ultrasonic excitations of high amplitude, and is required for ultrasound cavitation therapies. However, little is known about the distribution of nuclei in tissues. Therefore, the acoustic pressure level necessary to generate bubbles in a targeted zone and their exact location are currently difficult to predict. To monitor the initiation of cavitation activity, a novel all-ultrasound technique sensitive to single nucleation events is presented here. It is based on combined passive detection and ultrafast active imaging over a large volume using the same multi-element probe. Bubble nucleation was induced using a focused transducer (660 kHz, f-number = 1) driven by a high-power electric burst (up to 300 W) of one to two cycles. Detection was performed with a linear array (4 to 7 MHz) aligned with the single-element focal point. In vitro experiments in gelatin gel and muscular tissue are presented. The synchronized passive detection enabled radio-frequency data to be recorded, comprising high-frequency coherent wave fronts as signatures of the acoustic emissions linked to the activation of the nuclei. Active change detection images were obtained by subtracting echoes collected in the unnucleated medium. These indicated the appearance of stable cavitating regions. Because of the ultrafast frame rate, active detection occurred as quickly as 330 μs after the high-amplitude excitation and the dynamics of the induced regions were studied individually.

Combined passive detection and ultrafast active imaging of cavitation events induced by short pulses of high-intensity ultrasound

PubMed Central

Gateau, Jérôme; Aubry, Jean-François; Pernot, Mathieu; Fink, Mathias; Tanter, Mickaël

2011-01-01

The activation of natural gas nuclei to induce larger bubbles is possible using short ultrasonic excitations of high amplitude, and is required for ultrasound cavitation therapies. However, little is known about the distribution of nuclei in tissues. Therefore, the acoustic pressure level necessary to generate bubbles in a targeted zone and their exact location are currently difficult to predict. In order to monitor the initiation of cavitation activity, a novel all-ultrasound technique sensitive to single nucleation events is presented here. It is based on combined passive detection and ultrafast active imaging over a large volume and with the same multi-element probe. Bubble nucleation was induced with a focused transducer (660kHz, f#=1) driven by a high power (up to 300 W) electric burst of one to two cycles. Detection was performed with a linear array (4–7MHz) aligned with the single-element focal point. In vitro experiments in gelatin gel and muscular tissue are presented. The synchronized passive detection enabled radio-frequency data to be recorded, comprising high-frequency coherent wave fronts as signatures of the acoustic emissions linked to the activation of the nuclei. Active change detection images were obtained by subtracting echoes collected in the unucleated medium. These indicated the appearance of stable cavitating regions. Thanks to the ultrafast frame rate, active detection occurred as soon as 330 μs after the high amplitude excitation and the dynamics of the induced regions were studied individually. PMID:21429844

The observation of negative permittivity in stripe and bubble phases

NASA Astrophysics Data System (ADS)

Smet, Jurgen

The physics of itinerant two-dimensional electrons is by and large governed by repulsive Coulomb forces. However, cases exist where the interplay of attractive and repulsive interaction components may instigate spontaneous symmetry lowering and clustering of charges in geometric patterns such as bubbles and stripes, provided these interactions act on different length scales. The existence of these phases in higher Landau levels has so far been concluded from transport behavior. Here, we report surface acoustic wave experiments. They probe the permittivity at small wave vector. This technique offers true directionality, whereas in transport the current distribution is complex and strongly affected by the inhomogeneous density pattern. Outside the charge density wave regime, the measured permittivity is always positive. However, negative permittivity is observed in the bubble phase irrespective of the propagation direction. For the stripe phase the permittivity takes on both positive as well as negative values depending on the propagation direction. This confirms the stripe phase to be a strongly anisotropic medium. The observation of negative permittivity is considered an immediate consequence of the exchange related attractive interaction. It makes charge clustering favorable in higher Landau levels where the repulsive direct Coulomb interaction acts on a longer length scale and is responsible for a negative compressibility of the electronic system. This work has been carried out with B. Friess, K. von Klitzing (MPI-FKF), Y. Peng, F. von Oppen (FU Berlin), B. Rosenow (Uni Leipzig) and V. Umansky (Weizmann Institute of Science).

Laser-driven electron beam acceleration and future application to compact light sources

NASA Astrophysics Data System (ADS)

Hafz, N.; Jeong, T. M.; Lee, S. K.; Pae, K. H.; Sung, J. H.; Choi, I. W.; Yu, T. J.; Jeong, Y. U.; Lee, J.

2009-07-01

Laser-driven plasma accelerators are gaining much attention by the advanced accelerator community due to the potential these accelerators hold in miniaturizing future high-energy and medium-energy machines. In the laser wakefield accelerator (LWFA), the ponderomotive force of an ultrashort high intensity laser pulse excites a longitudinal plasma wave or bubble. Due to huge charge separation, electric fields created in the plasma bubble can be several orders of magnitude higher than those available in conventional microwave and RF-based accelerator facilities which are limited (up to ˜100 MV/m) by material breakdown. Therefore, if an electron bunch is injected into the bubble in phase with its field, it will gain relativistic energies within an extremely short distance. Here, in the LWFA we show the generation of high-quality and high-energy electron beams up to the GeV-class within a few millimeters of gas-jet plasmas irradiated by tens of terawatt ultrashort laser pulses. Thus we realize approximately four orders of magnitude acceleration gradients higher than available by conventional technology. As a practical application of the stable high-energy electron beam generation, we are planning on injecting the electron beams into a few-meters long conventional undulator in order to realize compact X-ray synchrotron (immediate) and FEL (future) light sources. Stable laser-driven electron beam and radiation devices will surely open a new era in science, medicine and technology and will benefit a larger number of users in those fields.

The Nucleation Rate of Single O2 Nanobubbles at Pt Nanoelectrodes.

PubMed

Soto, Álvaro Moreno; German, Sean R; Ren, Hang; van der Meer, Devaraj; Lohse, Detlef; Edwards, Martin A; White, Henry S

2018-06-13

Nanobubble nucleation is a problem that affects efficiency in electrocatalytic reactions since those bubbles can block the surface of the catalytic sites. In this article, we focus on the nucleation rate of O 2 nanobubbles resulting from the electrooxidation of H 2 O 2 at Pt disk nanoelectrodes. Bubbles form almost instantaneously when a critical peak current, i nb p , is applied, but for lower currents, bubble nucleation is a stochastic process in which the nucleation (induction) time, t ind , dramatically decreases as the applied current approaches i nb p , a consequence of the local supersaturation level, ζ, increasing at high currents. Here, by applying different currents below i nb p , nanobubbles take some time to nucleate and block the surface of the Pt electrode at which the reaction occurs, providing a means to measure the stochastic t ind . We study in detail the different conditions in which nanobubbles appear, concluding that the electrode surface needs to be preconditioned to achieve reproducible results. We also measure the activation energy for bubble nucleation, E a , which varies in the range from (6 to 30) kT, and assuming a spherically cap-shaped nanobubble nucleus, we determine the footprint diameter L = 8-15 nm, the contact angle to the electrode surface θ = 135-155°, and the number of O 2 molecules contained in the nucleus (50 to 900 molecules).

Rescuing the intracluster medium of NGC 5813

NASA Astrophysics Data System (ADS)

Soker, Noam; Hillel, Shlomi; Sternberg, Assaf

2016-06-01

We use recent X-ray observations of the intracluster medium (ICM) of the galaxy group NGC 5813 to confront theoretical studies of ICM thermal evolution with the newly derived ICM properties. We argue that the ICM of the cooling flow in the galaxy group NGC 5813 is more likely to be heated by mixing of post-shock gas from jets residing in hot bubbles with the ICM, than by shocks or turbulent-heating. Shocks thermalize only a small fraction of their energy in the inner regions of the cooling flow; in order to adequately heat the inner part of the ICM, they would overheat the outer regions by a large factor, leading to its ejection from the group. Heating by mixing, which was found to be much more efficient than turbulent-heating and shocks-heating, hence, rescues the outer ICM of NGC 5813 from its predestined fate according to cooling flow feedback scenarios that are based on heating by shocks.

Using one-dimensional waveguide resonators to measure phase velocities in bubbly liquids.

PubMed

Dolder, Craig N; Wilson, Preston S

2017-04-01

Resonator techniques can be successfully used to extract effective medium properties from dispersive materials. However, in some cases the dispersion can cause modes to repeat. If repeated modes are not taken into account, the useful range of the resonator technique is limited. A resonance tube containing tethered balloons is used to create a dispersive effective medium. Resonator measurements show that modes do repeat. Direct measurement of the mode shapes allows exploitation of all longitudinal radially symmetric modes and expands the frequency range of the technique. A theoretical model is also used to predict when modes repeat. For the presented data set this method increases the measurement range from below 160 Hz to 3000 Hz excluding the stop band where resonances are damped. A means to account for non-ideal resonator boundary conditions often found in highly dispersive systems is discussed.

ALESEP. Part 2: A computer program for the analysis of leading edge separation bubbles on infinite swept wings

NASA Technical Reports Server (NTRS)

Davis, R. L.

1986-01-01

A program called ALESEP is presented for the analysis of the inviscid-viscous interaction which occurs due to the presence of a closed laminar-transitional separation bubble on an airfoil or infinite swept wing. The ALESEP code provides an iterative solution of the boundary layer equations expressed in an inverse formulation coupled to a Cauchy integral representation of the inviscid flow. This interaction analysis is treated as a local perturbation to a known solution obtained from a global airfoil analysis; hence, part of the required input to the ALESEP code are the reference displacement thickness and tangential velocity distributions. Special windward differencing may be used in the reversed flow regions of the separation bubble to accurately account for the flow direction in the discretization of the streamwise convection of momentum. The ALESEP code contains a forced transition model based on a streamwise intermittency function, a natural transition model based on a solution of the integral form of the turbulent kinetic energy equation, and an empirical natural transition model.

Preliminary design for a standard 10 sup 7 bit Solid State Memory (SSM)

NASA Technical Reports Server (NTRS)

Hayes, P. J.; Howle, W. M., Jr.; Stermer, R. L., Jr.

1978-01-01

A modular concept with three separate modules roughly separating bubble domain technology, control logic technology, and power supply technology was employed. These modules were respectively the standard memory module (SMM), the data control unit (DCU), and power supply module (PSM). The storage medium was provided by bubble domain chips organized into memory cells. These cells and the circuitry for parallel data access to the cells make up the SMM. The DCU provides a flexible serial data interface to the SMM. The PSM provides adequate power to enable one DCU and one SMM to operate simultaneously at the maximum data rate. The SSM was designed to handle asynchronous data rates from dc to 1.024 Mbs with a bit error rate less than 1 error in 10 to the eight power bits. Two versions of the SSM, a serial data memory and a dual parallel data memory were specified using the standard modules. The SSM specification includes requirements for radiation hardness, temperature and mechanical environments, dc magnetic field emission and susceptibility, electromagnetic compatibility, and reliability.

Experimental and CFD-PBM approach coupled with a simplified dynamic analysis of mass transfer in phenol biodegradation in a three phase system of an aerated two-phase partitioning bioreactor for environmental applications

NASA Astrophysics Data System (ADS)

Moradkhani, Hamed; Anarjan Kouchehbagh, Navideh; Izadkhah, Mir-Shahabeddin

2017-03-01

A three-dimensional transient modeling of a two-phase partitioning bioreactor, combining system hydrodynamics, two simultaneous mass transfer and microorganism growth is modeled using computational fluid dynamics code FLUENT 6.2. The simulation is based on standard "k-ɛ" Reynolds-averaged Navier-Stokes model. Population balance model is implemented in order to describe gas bubble coalescence, breakage and species transport in the reaction medium and to predict oxygen volumetric mass transfer coefficient (kLa). Model results are verified against experimental data and show good agreement as 13 classes of bubble size is taking into account. Flow behavior in different operational conditions is studied. Almost at all impeller speeds and aeration intensities there were acceptable distributions of species caused by proper mixing. The magnitude of dissolved oxygen percentage in aqueous phase has a direct correlation with impeller speed and any increasing of the aeration magnitude leads to faster saturation in shorter periods of time.

Experimental investigation of plasma relaxation using a compact coaxial magnetized plasma gun in a background plasma

NASA Astrophysics Data System (ADS)

Zhang, Yue; Lynn, Alan; Gilmore, Mark; Hsu, Scott; University of New Mexico Collaboration; Los Alamos National Laboratory Collaboration

2013-10-01

A compact coaxial plasma gun is employed for experimental studies of plasma relaxation in a low density background plasma. Experiments are being conducted in the linear HelCat device at UNM. These studies will advance the knowledge of basic plasma physics in the areas of magnetic relaxation and space and astrophysical plasmas, including the evolution of active galactic jets/radio lobes within the intergalactic medium. The gun is powered by a 120pF ignitron-switched capacitor bank which is operated in a range of 5-10 kV and ~100 kA. Multiple diagnostics are employed to investigate plasma relaxation process. Magnetized Argon plasma bubbles with velocities ~1.2Cs and densities ~1020 m-3 have been achieved. Different distinct regimes of operation with qualitatively different dynamics are identified by fast CCD camera images, with the parameter determining the operation regime. Additionally, a B-dot probe array is employed to measure the spatial toroidal and poloidal magnetic flux evolution to identify detached plasma bubble configurations. Experimental data and analysis will be presented.

Heat transfer and hydrodynamic investigations of a baffled slurry bubble column

NASA Astrophysics Data System (ADS)

Saxena, S. C.; Chen, Z. D.

1992-09-01

Heat transfer and hydrodynamic investigations have been conducted in a 0.108 m internal diameter bubble column at ambient conditions. The column is equipped with seven 19mm diameter tubes arranged in an equilateral triangular pitch of 36.5 mm. A Monsanto synthetic heat transfer fluid, Therminol-66 having a viscosity of 39.8 cP at 303 K, is used as a liquid medium. Magnetite powders, average diameters 27.7 and 36.6 µm, in five concentrations up to 50 weight percent in the slurry, are used. As a gas phase, industrial grade nitrogen of purity 99.6 percent is employed. Gas holdup in different operating modes and regimes have been measured for the two- and three-phase systems over a superficial gas velocity range up to 0.20 m/s in the semi-batch mode. Heat transfer coefficients are measured at different tube locations in the bundle at different radial and vertical locations over a range of operating conditions. All these data are compared with the existing literature correlations and models. New correlations are proposed.

Influence of liquid medium on the activity of a low-alpha Fischer-Tropsch catalyst

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gormley, R.J.; Zarochak, M.F.; Deffenbaugh, P.W.

1995-12-31

The purpose of this research was to measure activity, selectivity, and the maintenance of these properties in slurry autoclave experiments with a Fischer-Tropsch (FT) catalyst that was used in the {open_quotes}FT II{close_quotes} bubble-column test, conducted at the Alternative Fuels Development Unit (AFDU) at LaPorte, Texas during May 1994. The catalyst contained iron, copper, and potassium and was formulated to produce mainly hydrocarbons in the gasoline range with lesser production of diesel-range products and wax. The probability of chain growth was thus deliberately kept low. Principal goals of the autoclave work have been to find the true activity of this catalystmore » in a stirred tank reactor, unhindered by heat or mass transfer effects, and to obtain a steady conversion and selectivity over the approximately 15 days of each test. Slurry autoclave testing of the catalyst in heavier waxes also allows insight into operation of larger slurry bubble column reactors. The stability of reactor operation in these experiments, particularly at loadings exceeding 20 weight %, suggests the likely stability of operations on a larger scale.« less

A High Space Density of Luminous Lyman Alpha Emitters at z ∼ 6.5

NASA Astrophysics Data System (ADS)

Bagley, Micaela B.; Scarlata, Claudia; Henry, Alaina; Rafelski, Marc; Malkan, Matthew; Teplitz, Harry; Dai, Y. Sophia; Baronchelli, Ivano; Colbert, James; Rutkowski, Michael; Mehta, Vihang; Dressler, Alan; McCarthy, Patrick; Bunker, Andrew; Atek, Hakim; Garel, Thibault; Martin, Crystal L.; Hathi, Nimish; Siana, Brian

2017-03-01

We present the results of a systematic search for Lyα emitters (LAEs) at 6≲ z≲ 7.6 using the HST WFC3 Infrared Spectroscopic Parallel (WISP) Survey. Our total volume over this redshift range is ∼ 8× {10}5 Mpc3, comparable to many of the narrowband surveys despite their larger area coverage. We find two LAEs at z = 6.38 and 6.44 with line luminosities of {L}Lyα }∼ 4.7× {10}43 erg s‑1, putting them among the brightest LAEs discovered at these redshifts. Taking advantage of the broad spectral coverage of WISP, we are able to rule out almost all lower-redshift contaminants. The WISP LAEs have a high number density of 7.7× {10}-6 Mpc‑3. We argue that the LAEs reside in megaparsec-scale ionized bubbles that allow the Lyα photons to redshift out of resonance before encountering the neutral intergalactic medium. We discuss possible ionizing sources and conclude that the observed LAEs alone are not sufficient to ionize the bubbles.

Long Time Evolution of Sequestered CO2 in Porous Media

NASA Astrophysics Data System (ADS)

Cohen, Y.; Rothman, D.

2013-12-01

CO2 sequestration is important for mitigating climate change and reducing atmospheric CO2 concentration. However, a complete physical picture able to predict both the pattern formation and the structure developing within the porous medium is lacking. We propose a theoretical model that couples transport, reaction, and the intricate geometry of the rock, in order to study the long time evolution of carbon in the brine-rock environment. As CO2 is injected into a brine-rock environment, it becomes initially trapped, and isolated bubbles are formed. Within the high CO2 phase, minerals dissolve and migrate from high concentration to low concentration regions, along with other carbonate species. The change in the concentrations at the interface moves the system out of equilibrium, drives up the saturation level, and leads to mineral precipitation. We argue that mineral precipitation in a small boundary layer may lead to lower diffusivity, slower kinetics, and eventually to a mechanical trapping of the CO2 bubbles. We investigate the reactive transport model and study the conditions that cause the mechanical separation of these two reactive fluids in porous media.

Controlled removal of ceramic surfaces with combination of ions implantation and ultrasonic energy

DOEpatents

Boatner, Lynn A.; Rankin, Janet; Thevenard, Paul; Romana, Laurence J.

1995-01-01

A method for tailoring or patterning the surface of ceramic articles is provided by implanting ions to predetermined depth into the ceramic material at a selected surface location with the ions being implanted at a fluence and energy adequate to damage the lattice structure of the ceramic material for bi-axially straining near-surface regions of the ceramic material to the predetermined depth. The resulting metastable near-surface regions of the ceramic material are then contacted with energy pulses from collapsing, ultrasonically-generated cavitation bubbles in a liquid medium for removing to a selected depth the ion-damaged near-surface regions containing the bi-axially strained lattice structure from the ceramic body. Additional patterning of the selected surface location on the ceramic body is provided by implanting a high fluence of high-energy, relatively-light ions at selected surface sites for relaxing the bi-axial strain in the near-surface regions defined by these sites and thereby preventing the removal of such ion-implanted sites by the energy pulses from the collapsing ultrasonic cavitation bubbles.

Nanoscale multiple gaseous layers on a hydrophobic surface.

PubMed

Zhang, Lijuan; Zhang, Xuehua; Fan, Chunhai; Zhang, Yi; Hu, Jun

2009-08-18

The nanoscale gas state at the interfaces of liquids (water, acid, and salt solutions) and highly oriented pyrolytic graphite (HOPG) was investigated via tapping-mode atomic force microscopy (AFM). For the first time, we report that the interfacial gases could form bilayers and trilayers, i.e., on the top of a flat gas layer, there are one or two more gas layers. The formation of these gas layers could be induced by a local supersaturation of gases, which can be achieved by (1) temperature difference between the liquids and the HOPG substrates or (2) exchange ethanol with water. Furthermore, we found that the gas layers were less stable than spherical bubbles. They could transform to bubbles with time or under the perturbation of the AFM tip.

Searching for 300, 000 Degree Gas in the Core of the Phoenix Cluster with HST-COS

NASA Astrophysics Data System (ADS)

McDonald, Michael

2013-10-01

The high central density of the intracluster medium in some galaxy clusters suggests that the hot 10,000,000K gas should cool completely in less than a Hubble time. In these clusters, simple cooling models predict 100-1000 solar masses per year of cooling gas should fuel massive starbursts in the central galaxy. The fact that the typical central cluster galaxy is a massive, "red and dead" elliptical galaxy, with little evidence for a cool ISM, has led to the realization of the "cooling flow problem". It is now thought that mechanical feedback from the central supermassive blackhole, in the form of radio-blown bubbles, is offsetting cooling, leading to an exceptionally precise {residuals of less than 10 percent} balance between cooling and feedback in nearly every galaxy cluster in the local Universe. In the recently-discovered Phoenix cluster, where z=0.596, we observe an 800 solar mass per year starburst within the central galaxy which accounts for about 30 percent of the classical cooling prediction for this system. We speculate that this may represent the first "true" cooling flow, with the factor of 3 difference between cooling and star formation being attributed to star formation efficiency, rather than a problem with cooling. In order to test these predictions, we propose far-UV spectroscopic observations of the OVI 1032A emission line, which probes 10^5.5K gas, in the central galaxy of the Phoenix cluster. If detected at the expected levels, this would provide compelling evidence that the starburst is, indeed, fueled by runaway cooling of the intracluster medium, confirming the presence of the first, bonafide cooling flow.

Chaotic bubbling and nonstagnant foams.

PubMed

Tufaile, Alberto; Sartorelli, José Carlos; Jeandet, Philippe; Liger-Belair, Gerard

2007-06-01

We present an experimental investigation of the agglomeration of bubbles obtained from a nozzle working in different bubbling regimes. This experiment consists of a continuous production of bubbles from a nozzle at the bottom of a liquid column, and these bubbles create a two-dimensional (2D) foam (or a bubble raft) at the top of this column. The bubbles can assemble in various dynamically stable arrangement, forming different kinds of foams in a liquid mixture of water and glycerol, with the effect that the bubble formation regimes influence the foam obtained from this agglomeration of bubbles. The average number of bubbles in the foam is related to the bubble formation frequency and the bubble mean lifetime. The periodic bubbling can generate regular or irregular foam, while a chaotic bubbling only generates irregular foam.

MOPRA CO OBSERVATIONS OF THE BUBBLE H II REGION RCW 120

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, L. D.; Deharveng, L.; Zavagno, A.

2015-02-20

We use the Mopra radio telescope to test for expansion of the molecular gas associated with the bubble H II region RCW 120. A ring, or bubble, morphology is common for Galactic H II regions, but the three-dimensional geometry of such objects is still unclear. Detected near- and far-side expansion of the associated molecular material would be consistent with a three-dimensional spherical object. We map the J = 1 → 0 transitions of {sup 12}CO, {sup 13}CO, C{sup 18}O, and C{sup 17}O, and detect emission from all isotopologues. We do not detect the 0{sub 0} → 1{sub –1} E masingmore » lines of CH{sub 3}OH at 108.8939 GHz. The strongest CO emission is from the photo-dissociation region (PDR), and there is a deficit of emission toward the bubble interior. We find no evidence for expansion of the molecular material associated with RCW 120 and therefore can make no claims about its geometry. The lack of detected expansion is roughly in agreement with models for the time-evolution of an H II region like RCW 120, and is consistent with an expansion speed of ≲ 1.5 km s{sup –1}. Single-position CO spectra show signatures of expansion, which underscores the importance of mapped spectra for such work. Dust temperature enhancements outside the PDR of RCW 120 coincide with a deficit of emission in CO, confirming that these temperature enhancements are due to holes in the RCW 120 PDR. H-alpha emission shows that RCW 120 is leaking ∼5% of the ionizing photons into the interstellar medium (ISM) through PDR holes at the locations of the temperature enhancements. Hα emission also shows a diffuse 'halo' from leaked photons not associated with discrete holes in the PDR. Overall ∼25% ± 10% of all ionizing photons are leaking into the nearby ISM.« less

Collective behavior of bulk nanobubbles produced by alternating polarity electrolysis.

PubMed

Postnikov, Alexander V; Uvarov, Ilia V; Penkov, Nikita V; Svetovoy, Vitaly B

2017-12-21

Nanobubbles in liquids are mysterious gaseous objects with exceptional stability. They promise a wide range of applications, but their production is not well controlled and localized. Alternating polarity electrolysis of water is a tool that can control the production of bulk nanobubbles in space and time without generating larger bubbles. Using the schlieren technique, the detailed three-dimensional structure of a dense cloud of nanobubbles above the electrodes is visualized. It is demonstrated that the thermal effects produce a different schlieren pattern and have different dynamics. A localized volume enriched with nanobubbles can be separated from the parent cloud and exists on its own. This volume demonstrates buoyancy, from which the concentration of nanobubbles is estimated as 2 × 10 18 m -3 . This concentration is smaller than that in the parent cloud. Dynamic light scattering shows that the average size of nanobubbles during the process is 60-80 nm. The bubbles are observed 15 minutes after switching off the electrical pulses but their size is shifted to larger values of about 250 nm. Thus, an efficient way to generate and control nanobubbles is proposed.

Research and Analysis on the Localization of a 3-D Single Source in Lossy Medium Using Uniform Circular Array

PubMed Central

Xue, Bing; Qu, Xiaodong; Fang, Guangyou; Ji, Yicai

2017-01-01

In this paper, the methods and analysis for estimating the location of a three-dimensional (3-D) single source buried in lossy medium are presented with uniform circular array (UCA). The mathematical model of the signal in the lossy medium is proposed. Using information in the covariance matrix obtained by the sensors’ outputs, equations of the source location (azimuth angle, elevation angle, and range) are obtained. Then, the phase and amplitude of the covariance matrix function are used to process the source localization in the lossy medium. By analyzing the characteristics of the proposed methods and the multiple signal classification (MUSIC) method, the computational complexity and the valid scope of these methods are given. From the results, whether the loss is known or not, we can choose the best method for processing the issues (localization in lossless medium or lossy medium). PMID:28574467

Approaching behavior of a pair of spherical bubbles in quiescent liquids

NASA Astrophysics Data System (ADS)

Sanada, Toshiyuki; Kusuno, Hiroaki

2015-11-01

Some unique motions related bubble-bubble interaction, such as equilibrium distance, wake induced lift force, have been proposed by theoretical analysis or numerical simulations. These motions are different from the solid spheres like DKT model (Drafting, Kissing and Tumbling). However, there is a lack of the experimental verification. In this study, we experimentally investigated the motion of a pair of bubbles initially positioned in-line configuration in ultrapure water or an aqueous surfactant solution. The bubble motion were observed by two high speed video cameras. The bubbles Reynolds number was ranged from 50 to 300 and bubbles hold the spherical shape in this range. In ultrapure water, initially the trailing bubble deviated from the vertical line on the leading bubble owing to the wake of the leading bubble. And then, the slight difference of the bubble radius changed the relative motion. When the trailing bubble slightly larger than the leading bubble, the trailing bubble approached to the leading bubble due to it's buoyancy difference. The bubbles attracted and collided only when the bubbles rising approximately side by side configuration. In addition, we will also discuss the motion of bubbles rising in an aqueous surfactant solution.

Beyond Pluto: The Search for the Edge of the Solar System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Funsten, Herb

In July, we finally visited the last major body of our solar system, Pluto. But what lies beyond? The stellar wind from our Sun forms an enormous bubble in interstellar space. This “sphere of our Sun,” or heliosphere, extends far beyond Pluto and forms a protective cocoon that shields us from cosmic radiation. In this talk, we will travel to the edge of the solar system, peer into the structure and dynamics of the outer heliosphere as it interacts with the interstellar medium and anticipate the future of the solar system as it moves through our galactic neighborhood.

FAR-ULTRAVIOLET OBSERVATIONS OF THE SPICA NEBULA AND THE INTERACTION ZONE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Choi, Yeon-Ju; Min, Kyoung-Wook; Lim, Tae-Ho

2013-09-01

We report the analysis results of far-ultraviolet (FUV) observations, made for a broad region around {alpha} Vir (Spica) including the interaction zone of Loop I and the Local Bubble. The whole region was optically thin and a general correlation was seen between the FUV continuum intensity and the dust extinction, except in the neighborhood of the bright central star, indicating the dust scattering nature of the FUV continuum. We performed Monte Carlo radiative transfer simulations to obtain the optical parameters related to the dust scattering as well as to the geometrical structure of the region. The albedo and asymmetry factormore » were found to be 0.38 {+-} 0.06 and 0.46 {+-} 0.06, respectively, in good agreement with the Milky Way dust grain models. The distance to and the thickness of the interaction zone were estimated to be 70{sup +4}{sub -8} pc and 40{sup +8}{sub -10} pc, respectively. The diffuse FUV continuum in the northern region above Spica was mostly the result of scattering of the starlight from Spica, while that in the southern region was mainly due to the background stars. The C IV {lambda}{lambda}1548, 1551 emission was found throughout the whole region, in contrast to the Si II* {lambda}1532 emission which was bright only within the H II region. This indicates that the C IV line arises mostly at the shell boundaries of the bubbles, with a larger portion likely from the Loop I than from the Local Bubble side, whereas the Si II* line is from the photoionized Spica Nebula.« less

Using an Acoustic System to Estimate the Timing and Magnitude of Ebullition Release from Wetland Ecosystems

NASA Astrophysics Data System (ADS)

Varner, R. K.; Palace, M. W.; Lennartz, J. M.; Crill, P. M.; Wik, M.; Amante, J.; Dorich, C.; Harden, J. W.; Ewing, S. A.; Turetsky, M. R.

2011-12-01

Knowledge of the magnitude and frequency of methane release through ebullition (bubbling) in water saturated ecosystems such as bogs, fens and lakes is important to both the atmospheric and ecosystems science community. The controls on episodic bubble releases must be identified in order to understand the response of these ecosystems to future climate forcing. We have developed and field tested an inexpensive array of sampling/monitoring instruments to identify the frequency and magnitude of bubbling events which allows us to correlate bubble data with potential drivers such as changes in hydrostatic pressure, wind and temperature. A prototype ebullition sensor has been developed and field tested at Sallie's Fen in New Hampshire, USA. The instrument consists of a nested, inverted funnel design with a hydrophone for detecting bubbles rising through the peat, that hit the microphone. The design also offers a way to sample the gases collected from the funnels to determine the concentration of CH4. Laboratory calibration of the instrument resulted in an equation that relates frequency of bubbles hitting the microphone with bubble volume. After calibration in the laboratory, the prototype was deployed in Sallie's Fen in late August 2010. An additional four instruments were deployed the following month. Audio data was recorded continuously using a digital audio recorder attached to two ebullition sensors. Audio was recorded as an mp3 compressed audio file at a sample rate of 160 kbits/sec. Using this format and stereo input, allowing for two sensors to be recorded with each device, we were able to record continuously for 20 days. Audio was converted to uncompressed audio files for speed in computation. Audio data was processed using MATLAB, searching in 0.5 second incremental sections for specific fundamental frequencies that are related to our calibrated audio events. Time, fundamental frequency, and estimated bubble size were output to a text file for analysis in statistical software. In addition, each event was cut out of the longer audio file and placed in a directory with number of ebullition event, sensor number, and time, allowing for manual interpretation of the ebullition event. After successful laboratory and local field testing, our instruments were deployed in summer 2011 at a temperate fen (Sallie's Fen, NH, USA), a subarctic mire and lake (Stordalen, Abisko, Sweden) and two locations in subarctic Alaska (APEX Research Site, Fairbanks, AK and Innoko National Wildlife Refuge). Ebullition occurred at regular intervals. Our results indicate that this is a useful method for monitoring CH4 ebullitive flux at high temporal frequencies.

[Practical advices in choosing local anesthesia tools in dentistry. Management of carpule's quality in local anesthesia in dentistry].

PubMed

Kuzin, A V

2014-01-01

The equipment for local anesthesia is described in this article. Practical recommendations for the selection of the injection needle length, size, bevel type is given. Using dental needle for local anesthesia should be guided by the "one injection - one needle" rule, as a needle tends to deform by even the slightest contact with jawbone. Some of the shortcomings of carpule quality may be detected before use: signs of cup corrosion, the presence of sediment, air bubbles, rubber plunger disposition. In the case of such defects being identified all the package should not be used. The use of such carpule in clinical practice is unsafe.

Interaction mechanism of double bubbles in hydrodynamic cavitation

NASA Astrophysics Data System (ADS)

Li, Fengchao; Cai, Jun; Huai, Xiulan; Liu, Bin

2013-06-01

Bubble-bubble interaction is an important factor in cavitation bubble dynamics. In this paper, the dynamic behaviors of double cavitation bubbles driven by varying pressure field downstream of an orifice plate in hydrodynamic cavitation reactor are examined. The bubble-bubble interaction between two bubbles with different radii is considered. We have shown the different dynamic behaviors between double cavitation bubbles and a single bubble by solving two coupling nonlinear equations using the Runge-Kutta fourth order method with adaptive step size control. The simulation results indicate that, when considering the role of the neighbor smaller bubble, the oscillation of the bigger bubble gradually exhibits a lag in comparison with the single-bubble case, and the extent of the lag becomes much more obvious as time goes by. This phenomenon is more easily observed with the increase of the initial radius of the smaller bubble. In comparison with the single-bubble case, the oscillation of the bigger bubble is enhanced by the neighbor smaller bubble. Especially, the pressure pulse of the bigger bubble rises intensely when the sizes of two bubbles approach, and a series of peak values for different initial radii are acquired when the initial radius ratio of two bubbles is in the range of 0.9˜1.0. Although the increase of the center distance between two bubbles can weaken the mutual interaction, it has no significant influence on the enhancement trend. On the one hand, the interaction between two bubbles with different radii can suppress the growth of the smaller bubble; on the other hand, it also can enhance the growth of the bigger one at the same time. The significant enhancement effect due to the interaction of multi-bubbles should be paid more attention because it can be used to reinforce the cavitation intensity for various potential applications in future.

49 CFR 611.205 - New Starts local financial commitment criteria.

Code of Federal Regulations, 2014 CFR

2014-10-01

...,” “medium,” “medium-low,” or “low.” The process by which the summary local financial commitment rating will... 49 Transportation 7 2014-10-01 2014-10-01 false New Starts local financial commitment criteria... § 611.205 New Starts local financial commitment criteria. In order to approve a grant under 49 U.S.C...

49 CFR 611.205 - New Starts local financial commitment criteria.

Code of Federal Regulations, 2013 CFR

2013-10-01

...,” “medium,” “medium-low,” or “low.” The process by which the summary local financial commitment rating will... 49 Transportation 7 2013-10-01 2013-10-01 false New Starts local financial commitment criteria... § 611.205 New Starts local financial commitment criteria. In order to approve a grant under 49 U.S.C...

Language Ideologies and Local Languages as the Medium-of-Instruction Policy: A Critical Ethnography of a Multilingual School in Nepal

ERIC Educational Resources Information Center

Phyak, Prem

2013-01-01

This paper analyzes the ideologies and practices of local languages as the medium-of-instruction (MOI) policy in a multilingual school in Nepal. Grounded on the notion of language policy as a locally situated social practice, this critical ethnographic study investigates challenges--both ideological and implementational--that local languages MOI…

Exploring the Dust Content of Galactic Winds with MIPS

NASA Astrophysics Data System (ADS)

Martin, Crystal; Engelbracht, Charles; Gordon, Karl

2005-06-01

This program explores the dust content of galactic winds. Nearly half of all stars in the universe probably form in a starburst event, where high concentrations of supernova explosions drive galactic-scale gaseous outflows. In nearby starburst galaxies, winds have been mapped at radio, optical, and X-ray frequencies revealing bipolar lobes of hot gas laced with cooler filaments bubbling out of the host galaxy. Most of the outflowing material is entrained interstellar gas, so it will remain quite dusty unless the grains are destroyed. Dusty winds have significant implications for the circulation of heavy elements in galaxies, the dust content of the intergalactic medium, and the acceleration of gaseous outflows. GALEX images of scattered ultraviolet light from galactic winds now provide compelling evidence for the survival of some grains. MIPS photometry of starburst winds at 24, 70, and 160 microns can, in principle, measure the dust temperature providing accurate estimates of the amount of dust (e.g. Engelbracht et al. 2004). To date, however, most MIPS observations of starburst galaxies are far too shallow to detect thermal emission from halo dust. The requested observations would provide the most sensitive observations currently possible for a sample of starburst galaxies, selected to span the full range of starburst luminosity and spatial geometry in the local universe.

Turbulent heating in galaxy clusters brightest in X-rays.

PubMed

Zhuravleva, I; Churazov, E; Schekochihin, A A; Allen, S W; Arévalo, P; Fabian, A C; Forman, W R; Sanders, J S; Simionescu, A; Sunyaev, R; Vikhlinin, A; Werner, N

2014-11-06

The hot (10(7) to 10(8) kelvin), X-ray-emitting intracluster medium (ICM) is the dominant baryonic constituent of clusters of galaxies. In the cores of many clusters, radiative energy losses from the ICM occur on timescales much shorter than the age of the system. Unchecked, this cooling would lead to massive accumulations of cold gas and vigorous star formation, in contradiction to observations. Various sources of energy capable of compensating for these cooling losses have been proposed, the most promising being heating by the supermassive black holes in the central galaxies, through inflation of bubbles of relativistic plasma. Regardless of the original source of energy, the question of how this energy is transferred to the ICM remains open. Here we present a plausible solution to this question based on deep X-ray data and a new data analysis method that enable us to evaluate directly the ICM heating rate from the dissipation of turbulence. We find that turbulent heating is sufficient to offset radiative cooling and indeed appears to balance it locally at each radius-it may therefore be the key element in resolving the gas cooling problem in cluster cores and, more universally, in the atmospheres of X-ray-emitting, gas-rich systems on scales from galaxy clusters to groups and elliptical galaxies.

Inner-ear decompression sickness: 'hubble-bubble' without brain trouble?

PubMed

Tremolizzo, Lucio; Malpieri, Massimo; Ferrarese, Carlo; Appollonio, Ildebrando

2015-06-01

Inner-ear decompression sickness (DCS) is an incompletely understood and increasingly recognized condition in compressed-air divers. Previous reports show a high association of inner-ear DCS with persistent foramen ovale (PFO), suggesting that a moderate-to-severe right-to-left shunt might represent a major predisposing factor, and more properly defining it as an event from arterial gas embolism (AGE). However, other conditions characterized by bubbles entering the arterial circulation, such as open-chamber cardiac surgery, do not produce inner-ear involvement, while sometimes damaging the brain extensively. Moreover, in other sites, such as the spinal cord, the prevailing mechanism for DCS is not AGE, but more likely local bubble formation with subsequent compression of venules and capillaries. Thus, AGE might be, more properly, a predisposing condition, neither sufficient, nor possibly even strictly necessary for inner-ear DCS. A 'two-hit hypothesis' has been proposed, implying a locally selective vulnerability of the inner ear to AGE. Modelled kinetics for gas removal are slower in the inner ear compared to the brain, leading to a supersaturated environment which allows bubbles to grow until they eventually obstruct the labyrinthine artery. Since this artery is relatively small, there is a low probability for a bubble to enter it; this might explain the disproportion between the high prevalence of PFO in the general population (25-30%) and the very low incidence of inner-ear DCS in compressed-air diving (approximately 0.005%). Furthermore, given that the labyrinthine artery usually originates either from the anterior inferior cerebellar artery, or directly from the basilar artery, shunting bubbles will more frequently swarm through the entire brain. In this case, however, the brain's much faster gas removal kinetics might allow for them to be reabsorbed without damaging brain tissue. In line with this scenario is the low probability (approx. 15%) of inner-ear DCS presenting with concomitant symptoms suggestive of brain involvement. Interestingly, PFO is a putative risk factor not only for DCS but also for ischaemic stroke, and it has been hypothesized that a predominantly silent ischaemic cerebral burden might represent a meaningful surrogate of end-organ damage in divers with PFO, with implications for stroke or cognitive decline. Here we report the case of a 44-year-old diving instructor (> 350 dives) who suffered from inner-ear DCS about 10 min after a routine dive (5 min/40 metres' fresh water (mfw), ascent 7.5 mfw·min⁻¹, stop 10 min/5 mfw), resulting in severe left cochlear/vestibular impairment (complete deafness and marked vertigo, only the latter slowly receding after a few hours). The patient was not recompressed. A few months later, transcranial Doppler ultrasonography demonstrated a moderate-to-severe shunt (> 30 bubbles), presumably due to a PFO (he refused confirmatory echocardiography), while a brain MRI (1.5 T) was reported as negative for both recent and remote lacunar infarcts (Figure 1). We believe this may be evidence that inner-ear DCS could occur while the brain is completely spared, not only clinically, but also at neuroimaging. This would support either of two hypotheses: (a) that the brain is indeed relatively protected from arterial bubbles that preferentially harm the inner ear where, however, they only rarely infiltrate, or (b) that direct bubble formation within the inner ear cannot be completely discarded, and that the elevated PFO-inner-ear DCS association might be, in this latter case, merely circumstantial. We favour the hypothesis that inner-ear DCS might be related to AGE in an anatomically vulnerable region. More precise data regarding the exact incidence of inner-ear involvement, isolating those subjects with moderate-to-severe shunt, should be obtained before exploring the risk-to-benefit ratio given by transcatheter occlusion of a PFO for prevention of inner-ear DCS; odds that could end up to be sensibly different with respect to other types of DCS presentation.

Investigation of the Temperature Fluctuation of Single-Phase Fluid Based Microchannel Heat Sink.

PubMed

Wang, Tao; Wang, Jiejun; He, Jian; Wu, Chuangui; Luo, Wenbo; Shuai, Yao; Zhang, Wanli; Lee, Chengkuo

2018-05-10

The temperature fluctuation in a single-phase microchannel heat sink (MCHS) is investigated using the integrated temperature sensors with deionized water as the coolant. Results show that the temperature fluctuation in single phase is not negligible. The causes of the temperature fluctuation are revealed based on both simulation and experiment. It is found that the inlet temperature fluctuation and the gas bubbles separated out from coolant are the main causes. The effect of the inlet temperature fluctuation is global, where the temperatures at different locations change simultaneously. Meanwhile, the gas bubble effect is localized where the temperature changes at different locations are not synchronized. In addition, the relation between temperature fluctuation and temperature gradient is established. The temperature fluctuation increases with the temperature gradient accordingly.

Visualization of airflow growing soap bubbles

NASA Astrophysics Data System (ADS)

Al Rahbi, Hamood; Bock, Matthew; Ryu, Sangjin

2016-11-01

Visualizing airflow inside growing soap bubbles can answer questions regarding the fluid dynamics of soap bubble blowing, which is a model system for flows with a gas-liquid-gas interface. Also, understanding the soap bubble blowing process is practical because it can contribute to controlling industrial processes similar to soap bubble blowing. In this study, we visualized airflow which grows soap bubbles using the smoke wire technique to understand how airflow blows soap bubbles. The soap bubble blower setup was built to mimic the human blowing process of soap bubbles, which consists of a blower, a nozzle and a bubble ring. The smoke wire was placed between the nozzle and the bubble ring, and smoke-visualized airflow was captured using a high speed camera. Our visualization shows how air jet flows into the growing soap bubble on the ring and how the airflow interacts with the soap film of growing bubble.

Integration of surface-active, periodically sequenced peptides into lipid-based microbubbles.

PubMed

Badami, Joseph V; Desir, Pierre; Tu, Raymond S

2014-07-29

The development of microbubbles toward functional, "theranostic" particles requires the incorporation of constituents with high binding specificity and therapeutic efficacy. Integrating peptides or proteins into the shell of lipid-based microbubbles can provide a means to access both receptor-ligand interactions and therapeutic properties. Simultaneously, peptides or proteins can define the characteristic monolayer mechanics of lipid bubbles and eliminate the need for post-bubble generation modification. The ability to engineer peptide sequences de novo that effectively partition into the bubble monolayer remains parametrically daunting. This work contributes to this effort using two simple amphipathic helical peptides that examine the role of local electrostatics and secondary structure. The two periodically sequenced peptides both have three positive charges, but peptide "K-2.5" spaces those charges 2.5 amino acids apart, while peptide "K-6.0" spaces the charges six amino acids apart. Size populations were determined for bubbles containing each peptide species using light scattering, and a quantitative method was developed to clearly define the fraction of peptides binding onto the microbubble monolayer. The impact of both the initial peptide concentration and the zwitterionic:anionic lipid ratio on peptide binding was also evaluated. Our results indicate that the lipid ratio affected only K-6.0 binding, which appears to be an outcome of the greater ensemble average α-helical population of the K-6.0. These findings provide further insights into the role of charge separation on peptide secondary structure, establishing a simple design metric for peptide binding onto microbubble systems.

Bubbles and denaturation in DNA

NASA Astrophysics Data System (ADS)

van Erp, T. S.; Cuesta-López, S.; Peyrard, M.

2006-08-01

The local opening of DNA is an intriguing phenomenon from a statistical-physics point of view, but is also essential for its biological function. For instance, the transcription and replication of our genetic code cannot take place without the unwinding of the DNA double helix. Although these biological processes are driven by proteins, there might well be a relation between these biological openings and the spontaneous bubble formation due to thermal fluctuations. Mesoscopic models, like the Peyrard-Bishop-Dauxois (PBD) model, have fairly accurately reproduced some experimental denaturation curves and the sharp phase transition in the thermodynamic limit. It is, hence, tempting to see whether these models could be used to predict the biological activity of DNA. In a previous study, we introduced a method that allows to obtain very accurate results on this subject, which showed that some previous claims in this direction, based on molecular-dynamics studies, were premature. This could either imply that the present PBD model should be improved or that biological activity can only be predicted in a more complex framework that involves interactions with proteins and super helical stresses. In this article, we give a detailed description of the statistical method introduced before. Moreover, for several DNA sequences, we give a thorough analysis of the bubble-statistics as a function of position and bubble size and the so-called l-denaturation curves that can be measured experimentally. These show that some important experimental observations are missing in the present model. We discuss how the present model could be improved.

Genome-wide identification and characterisation of human DNA replication origins by initiation site sequencing (ini-seq)

PubMed Central

Langley, Alexander R.; Gräf, Stefan; Smith, James C.; Krude, Torsten

2016-01-01

Next-generation sequencing has enabled the genome-wide identification of human DNA replication origins. However, different approaches to mapping replication origins, namely (i) sequencing isolated small nascent DNA strands (SNS-seq); (ii) sequencing replication bubbles (bubble-seq) and (iii) sequencing Okazaki fragments (OK-seq), show only limited concordance. To address this controversy, we describe here an independent high-resolution origin mapping technique that we call initiation site sequencing (ini-seq). In this approach, newly replicated DNA is directly labelled with digoxigenin-dUTP near the sites of its initiation in a cell-free system. The labelled DNA is then immunoprecipitated and genomic locations are determined by DNA sequencing. Using this technique we identify >25,000 discrete origin sites at sub-kilobase resolution on the human genome, with high concordance between biological replicates. Most activated origins identified by ini-seq are found at transcriptional start sites and contain G-quadruplex (G4) motifs. They tend to cluster in early-replicating domains, providing a correlation between early replication timing and local density of activated origins. Origins identified by ini-seq show highest concordance with sites identified by SNS-seq, followed by OK-seq and bubble-seq. Furthermore, germline origins identified by positive nucleotide distribution skew jumps overlap with origins identified by ini-seq and OK-seq more frequently and more specifically than do sites identified by either SNS-seq or bubble-seq. PMID:27587586

Genome-wide identification and characterisation of human DNA replication origins by initiation site sequencing (ini-seq).

PubMed

Langley, Alexander R; Gräf, Stefan; Smith, James C; Krude, Torsten

2016-12-01

Next-generation sequencing has enabled the genome-wide identification of human DNA replication origins. However, different approaches to mapping replication origins, namely (i) sequencing isolated small nascent DNA strands (SNS-seq); (ii) sequencing replication bubbles (bubble-seq) and (iii) sequencing Okazaki fragments (OK-seq), show only limited concordance. To address this controversy, we describe here an independent high-resolution origin mapping technique that we call initiation site sequencing (ini-seq). In this approach, newly replicated DNA is directly labelled with digoxigenin-dUTP near the sites of its initiation in a cell-free system. The labelled DNA is then immunoprecipitated and genomic locations are determined by DNA sequencing. Using this technique we identify >25,000 discrete origin sites at sub-kilobase resolution on the human genome, with high concordance between biological replicates. Most activated origins identified by ini-seq are found at transcriptional start sites and contain G-quadruplex (G4) motifs. They tend to cluster in early-replicating domains, providing a correlation between early replication timing and local density of activated origins. Origins identified by ini-seq show highest concordance with sites identified by SNS-seq, followed by OK-seq and bubble-seq. Furthermore, germline origins identified by positive nucleotide distribution skew jumps overlap with origins identified by ini-seq and OK-seq more frequently and more specifically than do sites identified by either SNS-seq or bubble-seq. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Double bubble with the big-bubble technique during deep anterior lamellar keratoplasty.

PubMed

Wise, Stephanie; Dubord, Paul; Yeung, Sonia N

2017-04-28

To report a case of intraoperative double bubble that formed during big-bubble DALK surgery in a patient with corneal scarring secondary to herpetic stromal keratitis. Case report. A 22 year old woman presented with a large corneal scar, likely secondary to previous herpetic stromal keratitis. She underwent big-bubble DALK surgery for visual rehabilitation. Intraoperatively, a mixed bubble with persistent type 2 bubble postoperatively was noted. The second bubble resorbed with clearance of the graft and good visual outcome after 6 weeks. This case report describes the unusual development of a mixed bubble during big-bubble DALK surgery. This graft cleared with resolution of the second bubble postoperatively without further surgical intervention.

HST STIS Spectroscopy of the Bubble Nebula, NGC 7635

NASA Astrophysics Data System (ADS)

Buckalew, B.; Dufour, R.; Ghavamian, P.; Hartigan, P.; Walter, D.; Hester, J.; Scowen, P.

1999-05-01

We report the results of longslit spectroscopy of the wind-blown bubble and photoevaporating knots around the O6.5iiif star BD+ 60(deg) 2522 made with the Space Telescope Imaging Spectrograph. The Of star is the primary ionizing source for the H ii region NGC 7635, located in the Perseus Arm. The spectra were taken through a 0.2'' x 52'' slit with low and medium resolution gratings covering the wavelength range 2900-6870 Angstroms. Observations with two slit orientations were made; one across the line of embedded knots to the west of the Of star and the second running from the Of star across the bubble to the NE. The 2D STIS spectra permit us to subtract the surrounding H ii region's diffuse emission from that of the knots and the bubble, and to study the spatial variations in various emission lines in these features to a resolution of ~ 0.1'', an order of magnitude improvement over the best ground-based spectra of this object in the literature. We present high spatial resolution emission line and line ratio profiles across the bubble and knots, and compare them with the predicted variations from photoionization, photoevaporation, and wind-shock models. We also present an analysis of temperatures, densities, and abundances in the features from higher S/N spectra extracted over selected lengths of the slit. From our analysis, we find that our measured abundances for nitrogen and oxygen are what we would expect for an H ii region at this galactocentric distance. However, the rim helium and carbon abundances show an enhancement which may be caused by contamination from the stellar wind. From our spatial scan studies of the knots and rim, we conclude that the knots are composed of photoevaporating knots surrounded by an ionization front, confirming the results of the imagery which indicate that the knots are like the EGGs of M16 seen face on. The rim appears to be the edge of a slightly supersonic shell of ionized gas that is being snowplowed through the surrounding H ii region by the star's supersonic wind. Acknowledgements. This research was supported in part by AURA/STScI grant GO-7515 and NASA-Ames grant NGT 2-52252.

Histotripsy Lesion Formation Using an Ultrasound Imaging Probe Enabled by a Low-Frequency Pump Transducer.

PubMed

Lin, Kuang-Wei; Hall, Timothy L; Xu, Zhen; Cain, Charles A

2015-08-01

When histotripsy pulses shorter than 2 cycles are applied, the formation of a dense bubble cloud relies only on the applied peak negative pressure (p-) exceeding the "intrinsic threshold" of the medium (absolute value of 26-30 MPa in most soft tissues). It has been found that a sub-threshold high-frequency probe pulse (3 MHz) can be enabled by a sub-threshold low-frequency pump pulse (500 kHz) where the sum exceeds the intrinsic threshold, thus generating lesion-producing dense bubble clouds ("dual-beam histotripsy"). Here, the feasibility of using an imaging transducer to provide the high-frequency probe pulse in the dual-beam histotripsy approach is investigated. More specifically, an ATL L7-4 imaging transducer (Philips Healthcare, Andover, MA, USA), pulsed by a V-1 Data Acquisition System (Verasonics, Redmond, WA, USA), was used to generate the high-frequency probe pulses. The low-frequency pump pulses were generated by a 20-element 345-kHz array transducer, driven by a custom high-voltage pulser. These dual-beam histotripsy pulses were applied to red blood cell tissue-mimicking phantoms at a pulse repetition frequency of 1 Hz, and optical imaging was used to visualize bubble clouds and lesions generated in the red blood cell phantoms. The results indicated that dense bubble clouds (and resulting lesions) were generated when the p- of the sub-threshold pump and probe pulses combined constructively to exceed the intrinsic threshold. The average size of the smallest reproducible lesions using the imaging probe pulse enabled by the sub-threshold pump pulse was 0.7 × 1.7 mm, whereas that using the supra-threshold pump pulse alone was 1.4 × 3.7 mm. When the imaging transducer was steered laterally, bubble clouds and lesions were steered correspondingly until the combined p- no longer exceeded the intrinsic threshold. These results were also validated with ex vivo porcine liver experiments. Using an imaging transducer for dual-beam histotripsy can have two advantages: (i) lesion steering can be achieved using the steering of the imaging transducer (implemented with the beamformer of the accompanying programmable ultrasound system), and (ii) treatment can be simultaneously monitored when the imaging transducer is used in conjunction with an ultrasound imaging system. Copyright © 2015 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

Histotripsy Lesion Formation using an Ultrasound Imaging Probe Enabled by a Low-Frequency Pump Transducer

PubMed Central

Lin, Kuang-Wei; Hall, Timothy L.; Xu, Zhen; Cain, Charles A.

2015-01-01

When applying histotripsy pulses shorter than 2 cycles, the formation of a dense bubble cloud only relies on the applied peak negative pressure (p-) exceeding the “intrinsic threshold” of the medium (absolute value of 26 – 30 MPa in most soft tissue). A previous study conducted by our research group showed that a sub-threshold high-frequency probe pulse (3 MHz) can be enabled by a sub-threshold low-frequency pump pulse (500 kHz) where the sum exceeds the intrinsic threshold, thus generating lesion-producing dense bubble clouds (“dual-beam histotripsy”). This paper investigates the feasibility of using an imaging transducer to provide the high-frequency probe pulse in the dual-beam histotripsy approach. More specifically, an ATL L7–4 imaging transducer, pulsed by a Verasonics V-1 Data Acquisition System, was used to generate the high-frequency probe pulses. The low-frequency pump pulses were generated by a 20-element 345 kHz array transducer, driven by a custom high voltage pulser. These dual-beam histotripsy pulses were applied to red-blood-cell (RBC) tissue-mimicking phantoms at a pulse repetition frequency of 1 Hz, and optical imaging was used to visualize bubble clouds and lesions generated in the RBC phantoms. The results showed that dense bubble clouds (and resulting lesions) were generated when the p- of the sub-threshold pump and probe pulses combined constructively to exceed the intrinsic threshold. The average size of the smallest reproducible lesions using the imaging probe pulse enabled by the sub-threshold pump pulse was 0.7 × 1.7 mm while that using the supra-threshold pump pulse alone was 1.4 × 3.7 mm. When the imaging transducer was steered laterally, bubble clouds and lesions were steered correspondingly until the combined p- no longer exceeded the intrinsic threshold. These results were also validated with ex vivo porcine liver experiments. Using an imaging transducer for dual-beam histotripsy can have two advantages, 1) lesion steering can be achieved using the steering of the imaging transducer (implemented with the beamformer of the accompanying programmable ultrasound system) and 2) treatment can be simultaneously monitored when the imaging transducer is used in conjunction with an ultrasound imaging system. PMID:25929995

Pore-scale study of multiphase reactive transport in fibrous electrodes of vanadium redox flow batteries

DOE PAGES

Chen, Li; He, YaLing; Tao, Wen -Quan; ...

2017-07-21

The electrode of a vanadium redox flow battery generally is a carbon fibre-based porous medium, in which important physicochemical processes occur. In this work, pore-scale simulations are performed to study complex multiphase flow and reactive transport in the electrode by using the lattice Boltzmann method (LBM). Four hundred fibrous electrodes with different fibre diameters and porosities are reconstructed. Both the permeability and diffusivity of the reconstructed electrodes are predicted and compared with empirical relationships in the literature. Reactive surface area of the electrodes is also evaluated and it is found that existing empirical relationship overestimates the reactive surface under lowermore » porosities. Further, a pore-scale electrochemical reaction model is developed to study the effects of fibre diameter and porosity on electrolyte flow, V II/V III transport, and electrochemical reaction at the electrolyte-fibre surface. Finally, evolution of bubble cluster generated by the side reaction is studied by adopting a LB multiphase flow model. Effects of porosity, fibre diameter, gas saturation and solid surface wettability on average bubble diameter and reduction of reactive surface area due to coverage of bubbles on solid surface are investigated in detail. It is found that gas coverage ratio is always lower than that adopted in the continuum model in the literature. Furthermore, the current pore-scale studies successfully reveal the complex multiphase flow and reactive transport processes in the electrode, and the simulation results can be further upscaled to improve the accuracy of the current continuum-scale models.« less

Observation of F region irregularities near a northern equatorial anomaly crest during solar minimum using ionosonde, GPS receiver, and satellites

NASA Astrophysics Data System (ADS)

Lee, C.-C.; Chen, W. S.; Chu, F. D.

2013-06-01

For solar minimum, the spread F, GPS phase fluctuations, and plasma bubbles near the crest of equatorial ionization anomaly (EIA) are simultaneously analyzed to investigate F region irregularities for the first time. The data were observed using the Chungli ionosonde, YMSM GPS receiver, and DMSP satellites during 1996. It is found that in the observed ionograms, the frequency spread F (FSF) usually comes after the range spread F (RSF) in a series of nighttime spread F events. This results in that the maximum occurrence of RSF appears before that of FSF in the nighttime variations in occurrence probabilities. Moreover, the seasonal variation for RSF is close to that for FSF. Both have a board maximum in the J-months and a secondary maximum in December. These indicate that RSF and FSF should be regarded as one type of spread F, which is the all spread F (ASF) in this study. Because the equatorial plasma bubbles occur infrequently during solar minimum, the F region irregularities forming ASF are not related to the equatorial spread F. On the other hand, the similarity in seasonal occurrence between ASF and medium-scale traveling ionospheric disturbances (MSTIDs) demonstrates that the F region irregularities near the EIA crest are mainly generated by the gradient drift instability driven by MSTIDs. The irregularities, generated by MSTIDs, mostly occur in the bottom side of the F region. Consequently, the events of significant GPS phase fluctuations and plasma bubble near the EIA crest are rare during 1996.