Accounting for methodological, structural, and parameter uncertainty in decision-analytic models: a practical guide.

PubMed

Bilcke, Joke; Beutels, Philippe; Brisson, Marc; Jit, Mark

2011-01-01

Accounting for uncertainty is now a standard part of decision-analytic modeling and is recommended by many health technology agencies and published guidelines. However, the scope of such analyses is often limited, even though techniques have been developed for presenting the effects of methodological, structural, and parameter uncertainty on model results. To help bring these techniques into mainstream use, the authors present a step-by-step guide that offers an integrated approach to account for different kinds of uncertainty in the same model, along with a checklist for assessing the way in which uncertainty has been incorporated. The guide also addresses special situations such as when a source of uncertainty is difficult to parameterize, resources are limited for an ideal exploration of uncertainty, or evidence to inform the model is not available or not reliable. for identifying the sources of uncertainty that influence results most are also described. Besides guiding analysts, the guide and checklist may be useful to decision makers who need to assess how well uncertainty has been accounted for in a decision-analytic model before using the results to make a decision.

Meeting the challenge of interpretation: Hearing the voices of people with intellectual and developmental disability through I-Poems.

PubMed

Corby, Deirdre; Taggart, Laurence; Cousins, Wendy

2018-06-01

Including the inner perspectives of people who have intellectual disability can pose methodological challenges to qualitative researchers. This article explains how the Listening Guide was applied as an additional step in the analysis during a study which used hermeneutic interviews with people with intellectual disability as the sole method of data collection. An argument is made for the systematic application of the guide with a focus on the use of I-Poems. This article advances qualitative methodological approaches and concludes that this method of drawing attention to the participants' own voices provides a unique basis for interpreting interviews and tasks researchers to examine the use of the Listening Guide.

Advanced Energy Retrofit Guide: Practical Ways to Improve Energy Performance; Grocery Stores (Revised) (Book)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hendron, B.

2013-07-01

The U.S. Department of Energy developed the Advanced Energy Retrofit Guides (AERGs) to provide specific methodologies, information, and guidance to help energy managers and other stakeholders successfully plan and execute energy efficiency improvements. Detailed technical discussion is fairly limited in these guides. Instead, we emphasize actionable information, practical methodologies, diverse case studies, and unbiased evaluations of the most promising retrofit measures for each building type. A series of AERGs is under development, addressing key segments of the commercial building stock. Grocery stores were selected as one of the highest priority sectors, because they represent one of the most energy-intensive marketmore » segments.« less

Traffic analysis toolbox volume XIII : integrated corridor management analysis, modeling, and simulation guide

DOT National Transportation Integrated Search

2017-02-01

As part of the Federal Highway Administration (FHWA) Traffic Analysis Toolbox (Volume XIII), this guide was designed to help corridor stakeholders implement the Integrated Corridor Management (ICM) Analysis, Modeling, and Simulation (AMS) methodology...

Traffic analysis toolbox volume XIII : integrated corridor management analysis, modeling, and simulation guide.

DOT National Transportation Integrated Search

2017-02-01

As part of the Federal Highway Administration (FHWA) Traffic Analysis Toolbox (Volume XIII), this guide was designed to help corridor stakeholders implement the Integrated Corridor Management (ICM) Analysis, Modeling, and Simulation (AMS) methodology...

Population health management guiding principles to stimulate collaboration and improve pharmaceutical care.

PubMed

Steenkamer, Betty; Baan, Caroline; Putters, Kim; van Oers, Hans; Drewes, Hanneke

2018-04-09

Purpose A range of strategies to improve pharmaceutical care has been implemented by population health management (PHM) initiatives. However, which strategies generate the desired outcomes is largely unknown. The purpose of this paper is to identify guiding principles underlying collaborative strategies to improve pharmaceutical care and the contextual factors and mechanisms through which these principles operate. Design/methodology/approach The evaluation was informed by a realist methodology examining the links between PHM strategies, their outcomes and the contexts and mechanisms by which these strategies operate. Guiding principles were identified by grouping context-specific strategies with specific outcomes. Findings In total, ten guiding principles were identified: create agreement and commitment based on a long-term vision; foster cooperation and representation at the board level; use layered governance structures; create awareness at all levels; enable interpersonal links at all levels; create learning environments; organize shared responsibility; adjust financial strategies to market contexts; organize mutual gains; and align regional agreements with national policies and regulations. Contextual factors such as shared savings influenced the effectiveness of the guiding principles. Mechanisms by which these guiding principles operate were, for instance, fostering trust and creating a shared sense of the problem. Practical implications The guiding principles highlight how collaboration can be stimulated to improve pharmaceutical care while taking into account local constraints and possibilities. The interdependency of these principles necessitates effectuating them together in order to realize the best possible improvements and outcomes. Originality/value This is the first study using a realist approach to understand the guiding principles underlying collaboration to improve pharmaceutical care.

Updated methods for traffic impact analysis, including evaluation of innovative intersection designs.

DOT National Transportation Integrated Search

2013-12-01

In 1992, an Applicants Guide and a Reviewers Guide to Traffic Impact Analyses to standardize the methodologies for conducting traffic : impact analyses (TIAs) in Indiana were developed for the Indiana Department of Transportation (INDOT). The m...

Asphalt materials characterization in support of implementation of the proposed mechanistic-empirical pavement design guide.

DOT National Transportation Integrated Search

2007-01-01

The proposed Mechanistic-Empirical Pavement Design Guide (MEPDG) procedure is an improved methodology for pavement design and evaluation of paving materials. Since this new procedure depends heavily on the characterization of the fundamental engineer...

Climate change and forest trees in the Pacific Northwest: guide to vulnerability assessment methodology

Treesearch

W. Devine; C. Aubry; J. Miller; K. Potter; A. Bower

2012-01-01

This guide provides a step-by-step description of the methodology used to apply the Forest Tree Genetic Risk Assessment System (ForGRAS; Potter and Crane 2010) to the tree species of the Pacific Northwest in a recent climate change vulnerability assessment (Devine et al. 2012). We describe our modified version of the ForGRAS model, and we review the model’s basic...

Response-Guided Community Detection: Application to Climate Index Discovery

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bello, Gonzalo; Angus, Michael; Pedemane, Navya

Discovering climate indices-time series that summarize spatiotemporal climate patterns-is a key task in the climate science domain. In this work, we approach this task as a problem of response-guided community detection; that is, identifying communities in a graph associated with a response variable of interest. To this end, we propose a general strategy for response-guided community detection that explicitly incorporates information of the response variable during the community detection process, and introduce a graph representation of spatiotemporal data that leverages information from multiple variables. We apply our proposed methodology to the discovery of climate indices associated with seasonal rainfall variability.more » Our results suggest that our methodology is able to capture the underlying patterns known to be associated with the response variable of interest and to improve its predictability compared to existing methodologies for data-driven climate index discovery and official forecasts.« less

Appendix 2. Guide for Running AgMIP Climate Scenario Generation Tools with R in Windows, Version 2.3

NASA Technical Reports Server (NTRS)

Hudson, Nicholas; Ruane, Alexander Clark

2013-01-01

This Guide explains how to create climate series and climate change scenarios by using the AgMip Climate team's methodology as outlined in the AgMIP Guide for Regional Assessment: Handbook of Methods and Procedures. It details how to: install R and the required packages to run the AgMIP Climate Scenario Generation scripts, and create climate scenarios from CMIP5 GCMs using a 30-year baseline daily weather dataset. The Guide also outlines a workflow that can be modified for application to your own climate data.

Liquid Pipeline Operator's Control Room Human Factors Risk Assessment and Management Guide

DOT National Transportation Integrated Search

2008-11-26

The purpose of this guide is to document methodologies, tools, procedures, guidance, and instructions that have been developed to provide liquid pipeline operators with an efficient and effective means of managing the human factors risks in their con...

Diffusion Strategy Guide.

ERIC Educational Resources Information Center

McCutcheon, James R.; Sanders, John R.

A methodology is presented for planning and managing the spread of educational innovations. The first portion of the guide develops a theoretical framework for diffusion which summarizes and capitalizes on the latest marketing and on the latest marketing and diffusion research findings. Major stages in the diffusion paradigm discussed include…

Monograph Bibliography Building in History.

ERIC Educational Resources Information Center

D'Aniello, Charles A.

An outline of reference works on history is presented, with emphasis on those bibliographies which provide appropriate research tools and methodologies without restriction to a particular library. The guide is presented in six sections. Section I identifies guides to bibliographies and sources of bibliographies including standard historical…

A Guide to Field Notes for Qualitative Research: Context and Conversation.

PubMed

Phillippi, Julia; Lauderdale, Jana

2018-02-01

Field notes are widely recommended in qualitative research as a means of documenting needed contextual information. With growing use of data sharing, secondary analysis, and metasynthesis, field notes ensure rich context persists beyond the original research team. However, while widely regarded as essential, there is not a guide to field note collection within the literature to guide researchers. Using the qualitative literature and previous research experience, we provide a concise guide to collection, incorporation, and dissemination of field notes. We provide a description of field note content for contextualization of an entire study as well as individual interviews and focus groups. In addition, we provide two "sketch note" guides, one for study context and one for individual interviews or focus groups for use in the field. Our guides are congruent with many qualitative and mixed methodologies and ensure contextual information is collected, stored, and disseminated as an essential component of ethical, rigorous qualitative research.

Young Children's Development of Scientific Knowledge Through the Combination of Teacher-Guided Play and Child-Guided Play

NASA Astrophysics Data System (ADS)

Sliogeris, Marija; Almeida, Sylvia Christine

2017-09-01

Play-based approaches to science learning allow children to meaningfully draw on their everyday experiences and activities as they explore science concepts in context. Acknowledging the crucial role of the teacher in facilitating science learning through play, the purpose of this qualitative study was to examine how teacher-guided play, in conjunction with child-guided play, supports children's development of science concepts. While previous research on play-based science learning has mainly focused on preschool settings, this study explores the possibilities of play-based approaches to science in primary school contexts. Using a qualitative methodology grounded in the cultural-historical theoretical perspective, children's learning was examined during a science learning sequence that combined teacher-guided and child-guided play. This study revealed that the teacher-guided play explicitly introduced science concepts which children then used and explored in subsequent child-guided play. However, intentional teaching during the child-guided play continued to be important. Play-based approaches to science allowed children to make sense of the science concepts using familiar, everyday knowledge and activities. It became evident that the expectations and values communicated through classroom practices influenced children's learning through play.

Introductory Guide to the Statistics of Molecular Genetics

ERIC Educational Resources Information Center

Eley, Thalia C.; Rijsdijk, Fruhling

2005-01-01

Background: This introductory guide presents the main two analytical approaches used by molecular geneticists: linkage and association. Methods: Traditional linkage and association methods are described, along with more recent advances in methodologies such as those using a variance components approach. Results: New methods are being developed all…

Policy options evaluation tool for managed lanes (POET-ML) users guide and methodology description : Federal Highway Administration HOV lane performance

DOT National Transportation Integrated Search

2008-12-01

Users guide for a sketch planning tool for exploring policy alternatives. It is intended for an audience of transportation professionals responsible for planning, designing, funding, operating, enforcing, monitoring, and managing HOV and HOT lanes...

Daytime School Guided Visits to an Astronomical Observatory in Brazil

ERIC Educational Resources Information Center

Colombo, Pedro Donizete, Jr.; Silva, Cibelle Celestino; Aroca, Silvia Calbo

2010-01-01

This article analyzes the activity "Daytime School Guided Visits" at an astronomical observatory in Brazil with pupils from primary school. The adopted research methodology relied on questionnaire applications and semistructured interviews. The objectives were to identify the influences of the visits on learning of astronomical concepts…

Promoting Teachers' Moral Reasoning and Collaborative Inquiry Performance: A Developmental Role-Taking and Guided Inquiry Study.

ERIC Educational Resources Information Center

Reiman, Alan J.; Peace, Sandra DeAngelis

2002-01-01

Discusses a study involving experienced teachers that illustrates a developmental methodology for promoting technical performance dimensions and moral and conceptual reasoning. Argues this learning-teaching framework (LTF) uses role taking, guided inquiry, balance, support and challenge, continuity and instructional coaching in educational…

A Field Guide for Sign Language Research.

ERIC Educational Resources Information Center

Stokoe, William; Kuschel, Rolf

Field researchers of sign language are the target of this methodological guide. The prospective researcher is briefed on the rationale of sign language study as language study and as distinct from the study of kinesics. Subjects covered include problems of translating, use of interpreters, and ethics. Instruments for obtaining social and language…

Precision-Guided Munitions Effects Representation

DTIC Science & Technology

2017-01-03

Center for Army Analysis (CAA) by the TRADOC Analysis Center, Monterey (TRAC-MTRY). The focus of the research is to improve the current methodology ... Methodology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . A-2 Timeline... Methodology . . . . . . . . . . . . . . . . . . . . C-1 MATLAB Code . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . C-49 Damage

DOE Office of Scientific and Technical Information (OSTI.GOV)

Petruccelli, Umberto, E-mail: umberto.petruccelli@unibas.it

Many studies about the external costs generated by the transport system have been developed in the last twenty years. To standardize methodologies and assessment procedures to be used in the evaluation of the projects, some European countries recently have adopted specific guidelines that differ from each other in some aspects even sensibly. This paper presents a critical analysis of the British, Italian and German guidelines and is aimed at cataloguing the external cost types regarded and the assessment methods indicated as well as to highlight the differences of the results, in terms of applicability and reliability. The goal is tomore » contribute to a European standardization process that would lead to the drafting of guidelines suited for all EU countries. - Highlights: • The analyzed guidelines agree on the methods to evaluate costs from air pollution, greenhouse gases and accidents. • They recommend respectively: dose-resp. approach; costs to reduce/permit emissions; whole direct, indirect and social costs. • For noise, DE guide indicates defensive expenditure or SP methods; IT guide, SP method; UK guide, the hedonic prices one. • For on territory impact, DE guide regards only the barrier effect; the IT one, also the soil consumption and system effects. • British guide proposes a qualitative methodology to estimate the impact on various landscapes and environments.« less

Reliable vision-guided grasping

NASA Technical Reports Server (NTRS)

Nicewarner, Keith E.; Kelley, Robert B.

1992-01-01

Automated assembly of truss structures in space requires vision-guided servoing for grasping a strut when its position and orientation are uncertain. This paper presents a methodology for efficient and robust vision-guided robot grasping alignment. The vision-guided grasping problem is related to vision-guided 'docking' problems. It differs from other hand-in-eye visual servoing problems, such as tracking, in that the distance from the target is a relevant servo parameter. The methodology described in this paper is hierarchy of levels in which the vision/robot interface is decreasingly 'intelligent,' and increasingly fast. Speed is achieved primarily by information reduction. This reduction exploits the use of region-of-interest windows in the image plane and feature motion prediction. These reductions invariably require stringent assumptions about the image. Therefore, at a higher level, these assumptions are verified using slower, more reliable methods. This hierarchy provides for robust error recovery in that when a lower-level routine fails, the next-higher routine will be called and so on. A working system is described which visually aligns a robot to grasp a cylindrical strut. The system uses a single camera mounted on the end effector of a robot and requires only crude calibration parameters. The grasping procedure is fast and reliable, with a multi-level error recovery system.

Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review

PubMed Central

Antoniou, Miranta; Jorgensen, Andrea L; Kolamunnage-Dona, Ruwanthi

2016-01-01

Background Personalized medicine is a growing area of research which aims to tailor the treatment given to a patient according to one or more personal characteristics. These characteristics can be demographic such as age or gender, or biological such as a genetic or other biomarker. Prior to utilizing a patient’s biomarker information in clinical practice, robust testing in terms of analytical validity, clinical validity and clinical utility is necessary. A number of clinical trial designs have been proposed for testing a biomarker’s clinical utility, including Phase II and Phase III clinical trials which aim to test the effectiveness of a biomarker-guided approach to treatment; these designs can be broadly classified into adaptive and non-adaptive. While adaptive designs allow planned modifications based on accumulating information during a trial, non-adaptive designs are typically simpler but less flexible. Methods and Findings We have undertaken a comprehensive review of biomarker-guided adaptive trial designs proposed in the past decade. We have identified eight distinct biomarker-guided adaptive designs and nine variations from 107 studies. Substantial variability has been observed in terms of how trial designs are described and particularly in the terminology used by different authors. We have graphically displayed the current biomarker-guided adaptive trial designs and summarised the characteristics of each design. Conclusions Our in-depth overview provides future researchers with clarity in definition, methodology and terminology for biomarker-guided adaptive trial designs. PMID:26910238

Feminist-informed participatory action research: a methodology of choice for examining critical nursing issues.

PubMed

Corbett, Andrea M; Francis, Karen; Chapman, Ysanne

2007-04-01

Identifying a methodology to guide a study that aims to enhance service delivery can be challenging. Participatory action research offers a solution to this challenge as it both informs and is informed by critical social theory. In addition, using a feminist lens helps acquiesce this approach as a suitable methodology for changing practice. This methodology embraces empowerment self-determination and the facilitation of agreed change as central tenets that guide the research process. Encouraged by the work of Foucault, Friere, Habermas, and Maguire, this paper explicates the philosophical assumptions underpinning critical social theory and outlines how feminist influences are complimentary in exploring the processes and applications of nursing research that seeks to embrace change.

Ultrasound- versus Palpation-Guided Injection of Corticosteroid for Plantar Fasciitis: A Meta-Analysis

PubMed Central

Yu, Aixi; Qi, Baiwen

2014-01-01

Background It is controversial whether ultrasound-guided injection of corticosteroid is superior to palpation-guided injection for plantar fasciitis. This meta-analysis was performed to compare the effectiveness of ultrasound-guided and palpation-guided injection of corticosteroid for the treatment of plantar fasciitis. Methods Databases (MEDLINE, Cochrane library and EMBASE) and reference lists were searched from their establishment to August 30, 2013 for randomized controlled trials (RCTs) comparing ultrasound-guided with palpation-guided injection for plantar fasciitis. The Cochrane risk of bias (ROB) tool was used to assess the methodological quality. Outcome measurements were visual analogue scale (VAS), tenderness threshold (TT), heel tenderness index (HTI), response rate, plantar fascia thickness (PFT), hypoechogenicity and heel pad thickness (HPT). The statistical analysis was performed with software RevMan 5.2 and Stata 12.0. When I2<50%, the fixed-effects model was adopted. Otherwise the randomized-effects model was adopted. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) system was used to assess the quality of evidence. Results Five RCTs with 149 patients were identified and analyzed. Compared with palpation-guided injection, ultrasound-guided injection was superior with regard to VAS, TT, response rate, PFT and hypoechogenicity. However, there was no statistical significance between the two groups for HPT and HTI. Conclusion Ultrasound-guided injection of corticosteroid tends to be more effective than palpation-guided injection. However, it needs to be confirmed by further research. PMID:24658102

Choosing phenomenology as a guiding philosophy for nursing research.

PubMed

Matua, Gerald Amandu

2015-03-01

To provide an overview of important methodological considerations that nurse researchers need to adhere to when choosing phenomenology as a guiding philosophy and research method. Phenomenology is a major philosophy and research method in the humanities, human sciences and arts disciplines with a central goal of describing people's experiences. However, many nurse researchers continue to grapple with methodological issues related to their choice of phenomenological method. The author conducted online and manual searches of relevant research books and electronic databases. Using an integrative method, peer-reviewed research and discussion papers published between January 1990 and December 2011 and listed in the CINAHL, Science Direct, PubMed and Google Scholar databases were reviewed. In addition, textbooks that addressed research methodologies such as phenomenology were used. Although phenomenology is widely used today to broaden understanding of human phenomena relevant to nursing practice, nurse researchers often fail to adhere to acceptable scientific and phenomenological standards. Cognisant of these challenges, researchers are expected to indicate in their work the focus of their investigations, designs, and approaches to collecting and analysing data. They are also expected to present their findings in an evocative and expressive manner. Choosing phenomenology requires researchers to understand it as a philosophy, including basic assumptions and tenets of phenomenology as a research method. This awareness enables researchers, especially novices, to make important methodological decisions, particularly those necessary to indicate the study's scientific rigour and phenomenological validity. This paper adds to the discussion of phenomenology as a guiding philosophy for nursing research. It aims to guide new researchers on important methodological decisions they need to make to safeguard their study's scientific rigour and phenomenological validity.

The Navigation Guide Systematic Review Methodology: A Rigorous and Transparent Method for Translating Environmental Health Science into Better Health Outcomes

PubMed Central

Sutton, Patrice

2014-01-01

Background: Synthesizing what is known about the environmental drivers of health is instrumental to taking prevention-oriented action. Methods of research synthesis commonly used in environmental health lag behind systematic review methods developed in the clinical sciences over the past 20 years. Objectives: We sought to develop a proof of concept of the “Navigation Guide,” a systematic and transparent method of research synthesis in environmental health. Discussion: The Navigation Guide methodology builds on best practices in research synthesis in evidence-based medicine and environmental health. Key points of departure from current methods of expert-based narrative review prevalent in environmental health include a prespecified protocol, standardized and transparent documentation including expert judgment, a comprehensive search strategy, assessment of “risk of bias,” and separation of the science from values and preferences. Key points of departure from evidence-based medicine include assigning a “moderate” quality rating to human observational studies and combining diverse evidence streams. Conclusions: The Navigation Guide methodology is a systematic and rigorous approach to research synthesis that has been developed to reduce bias and maximize transparency in the evaluation of environmental health information. Although novel aspects of the method will require further development and validation, our findings demonstrated that improved methods of research synthesis under development at the National Toxicology Program and under consideration by the U.S. Environmental Protection Agency are fully achievable. The institutionalization of robust methods of systematic and transparent review would provide a concrete mechanism for linking science to timely action to prevent harm. Citation: Woodruff TJ, Sutton P. 2014. The Navigation Guide systematic review methodology: a rigorous and transparent method for translating environmental health science into better health outcomes. Environ Health Perspect 122:1007–1014; http://dx.doi.org/10.1289/ehp.1307175 PMID:24968373

Towards Culturally Relevant Classroom Science: A Theoretical Framework Focusing on Traditional Plant Healing

ERIC Educational Resources Information Center

Mpofu, Vongai; Otulaja, Femi S.; Mushayikwa, Emmanuel

2014-01-01

A theoretical framework is an important component of a research study. It grounds the study and guides the methodological design. It also forms a reference point for the interpretation of the research findings. This paper conceptually examines the process of constructing a multi-focal theoretical lens for guiding studies that aim to accommodate…

A Land Manager's Guide to Point Counts of Birds in the Southeast

Treesearch

Paul B. Hamel; Winston P. Smith; Daniel J. Twedt; James R. Woehr; Eddie Morris; Robert B. Hamilton; Robert J. Cooper

1996-01-01

Current widespread concern for the status of neotropical migratory birds has sparked interest in techniques for inventorying and monitoring populations of these and other birds in southeastern forest habitats. The present guide gives detailed instructions for conducting point counts of birds. It further presents a detailed methodology for the design and conduct of...

Improving Second Grade Student's Reading Fluency and Comprehension Using Teacher-Guided iPad® App Instruction

ERIC Educational Resources Information Center

Redcay, Jessica D.; Preston, Sean M.

2016-01-01

Purpose: This study aims to examine the differences in second grade students' reading fluency and comprehension scores when using varying levels of teacher-guided iPad® app instruction to determine effective reading practices. Design/methodology/approach: This study reports the results of the quasi-experimental pre-post study by providing…

Development of Professional Confidence in Health Education: Research Evidence of the Impact of Guided Practice into the Profession

ERIC Educational Resources Information Center

Hecimovich, Mark; Volet, Simone

2011-01-01

Purpose: The purpose of this paper is to review critically the published research investigating how guided practice into the profession contributes to increased professional confidence in health care students, with a view to identifying its impact on the development of professional confidence. Design/methodology/approach: A literature search was…

Self-Guided Reading: Touch-Based Measures of Syntactic Processing

ERIC Educational Resources Information Center

Hatfield, Hunter

2016-01-01

A novel online reading methodology termed Self-Guided Reading (SGR) is examined to determine if it can successfully detect well-studied syntactic processing behaviours. In SGR, a participant runs their finger under masked text in order to reveal a sentence. It is therefore similar to self-paced reading in presentation of stimuli, but different in…

Effect of Guided Collaboration on General and Special Educators' Perceptions of Collaboration and Student Achievement

ERIC Educational Resources Information Center

Laine, Sandra

2013-01-01

This study investigated the effects of a guided collaboration approach during professional learning community meetings (PLC's) on the perceptions of general and special educators as well as the effect on student performance as measured by benchmark evaluation. A mixed methodology approach was used to collect data through surveys, weekly…

Guided Imagery as a Treatment Option for Fatigue

PubMed Central

Menzies, Victoria; Jallo, Nancy

2013-01-01

Purpose Fatigue is one of the most common complaints experienced among the general population. Because fatigue is recognized as a biobehavioral occurrence, a biobehavioral intervention such as guided imagery may be effective in reducing self-reported fatigue. Therefore, the purpose of this study was to explore the research literature related to the use of guided imagery as a nonpharmacological mind-body intervention for the symptom of fatigue. Method The electronic databases MEDLINE, CINAHL, PsychInfo, Psychology and Behavioral Sciences Collection and the Cochrane Library were searched from January 1980 to June 2010. Findings Of 24 articles retrieved, eight met the inclusion criteria and were included in this systematic literature review. Findings were inconsistent regarding the effectiveness of guided imagery on fatigue. Studies varied in study length, duration of the applied guided imagery intervention, dosage, and whether the images were targeted to the purpose of the intervention. Implications Guided imagery is a simple, economic intervention with the potential to effectively treat fatigue, thus further research is warranted using systematic, well-designed methodologies Standardizing guided imagery interventions according to total duration of exposure and targeted imagery in a variety of different populations adequately powered to detect changes will contribute to and strengthen nursing’s symptom-management armamentarium. PMID:21772047

Advanced Energy Retrofit Guide: Practical Ways to Improve Energy Performance, K-12 Schools (Book)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The U.S. Department of Energy developed the K-12 Advanced Energy Retrofit Guide to provide specific methodologies, information, and guidance to help energy managers and other stakeholders plan and execute energy efficiency improvements. We emphasize actionable information, practical methodologies, diverse case studies, and unbiased evaluation of the most promising retrofit measure for each building type. K-12 schools were selected as one of the highest priority building sectors, because schools affect the lives of most Americans. They also represent approximately 8% of the energy use and 10% of the floor area in commercial buildings.

The Nature of a Literacy-Based Tutoring Program for At-Risk Youth: Mentorship, Professional Development, and Implementation

ERIC Educational Resources Information Center

Lopez-Guerra, Maria Asusena

2013-01-01

The purpose of this research was to gain and provide an in-depth, holistic description and interpretation of the knowledge and literacy instruction tutors at Readers Advance provide students. Guided by a post-positivist realist framework and grounded theory methodology, qualitative inquiry design strategies were used to guide this research. This…

A User's Guide to CGNS. 1.0

NASA Technical Reports Server (NTRS)

Rumsey, Christopher L.; Poirier, Diane M. A.; Bush, Robert H.; Towne, Charles E.

2001-01-01

The CFD General Notation System (CGNS) was developed to be a self-descriptive, machine-independent standard for storing CFD aerodynamic data. This guide aids users in the implementation of CGNS. It is intended as a tutorial on the usage of the CGNS mid-level library routines for reading and writing grid and flow solution datasets for both structured and unstructured methodologies.

The NAEP Guide: A Description of the Content and Methods of the 1994 and 1996 Assessments. Revised Edition.

ERIC Educational Resources Information Center

Ballator, Nada

This guide to the National Assessment of Educational Progress (NAEP) describes its purpose, contents, uses, and research methodology by presenting 21 questions about the NAEP program. The NAEP is mandated by Congress to survey the educational accomplishments of U.S. students and to monitor changes in these accomplishments. It tracks the…

Tennessee long-range transportation plan : project evaluation system

DOT National Transportation Integrated Search

2005-12-01

The Project Evaluation System (PES) Report is an analytical methodology to aid programming efforts and prioritize multimodal investments. The methodology consists of both quantitative and qualitative evaluation criteria built upon the Guiding Princip...

Jobs and Economic Development Impact (JEDI) Model Geothermal User Reference Guide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, C.; Augustine, C.; Goldberg, M.

2012-09-01

The Geothermal Jobs and Economic Development Impact (JEDI) model, developed through the National Renewable Energy Laboratory (NREL), is an Excel-based user-friendly tools that estimates the economic impacts of constructing and operating hydrothermal and Enhanced Geothermal System (EGS) power generation projects at the local level for a range of conventional and renewable energy technologies. The JEDI Model Geothermal User Reference Guide was developed to assist users in using and understanding the model. This guide provides information on the model's underlying methodology, as well as the parameters and references used to develop the cost data utilized in the model. This guide alsomore » provides basic instruction on model add-in features, operation of the model, and a discussion of how the results should be interpreted.« less

Los Alamos National Laboratory: A guide to records series supporting epidemiologic studies conducted for the Department of Energy

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-01-01

The purpose of this guide is to describe each series of records that pertains to the epidemiologic studies conducted by the Epidemiology Section of the Occupational Medicine Group (ESH-2) at the Department of Energy`s (DOE) Los Alamos National Laboratory (LANL) in Los Alamos, New Mexico. The records described in this guide relate to occupational studies performed by the Epidemiology Section, including those pertaining to workers at LANL, Mound Plant, Oak Ridge Reservation, Pantex Plant, Rocky Flats Plant, and Savannah River Site. Also included are descriptions of other health-related records generated or collected by the Epidemiology Section and a small setmore » of records collected by the Industrial Hygiene and Safety Group. This guide is not designed to describe the universe of records generated by LANL which may be used for epidemiologic studies of the LANL work force. History Associates Incorporated (HAI) prepared this guide as part of its work as the support services contractor for DOE`s Epidemiologic Records Inventory Project. This introduction briefly describes the Epidemiologic Records Inventory Project, HAI`s role in the project, the history of LANL the history and functions of LANL`s Health Division and Epidemiology Section, and the various epidemiologic studies performed by the Epidemiology Section. It provides information on the methodology that HAI used to inventory and describe records housed in the offices of the LANL Epidemiology Section in Technical Area 59 and at the LANL Records Center. Other topics include the methodology used to produce the guide, the arrangement of the detailed record series descriptions, and information concerning access to records repositories.« less

A Novel Approach of Groupwise fMRI-Guided Tractography Allowing to Characterize the Clinical Evolution of Alzheimer's Disease

PubMed Central

Preti, Maria Giulia; Makris, Nikos; Papadimitriou, George; Laganà, Maria Marcella; Griffanti, Ludovica; Clerici, Mario; Nemni, Raffaello; Westin, Carl-Fredrik; Baselli, Giuseppe; Baglio, Francesca

2014-01-01

Guiding diffusion tract-based anatomy by functional magnetic resonance imaging (fMRI), we aim to investigate the relationship between structural connectivity and functional activity in the human brain. To this purpose, we introduced a novel groupwise fMRI-guided tractographic approach, that was applied on a population ranging between prodromic and moderate stages of Alzheimer's disease (AD). The study comprised of 15 subjects affected by amnestic mild cognitive impairment (aMCI), 14 diagnosed with AD and 14 elderly healthy adults who were used as controls. By creating representative (ensemble) functionally guided tracts within each group of participants, our methodology highlighted the white matter fiber connections involved in verbal fluency functions for a specific population, and hypothesized on brain compensation mechanisms that potentially counteract or reduce cognitive impairment symptoms in prodromic AD. Our hope is that this fMRI-guided tractographic approach could have potential impact in various clinical studies, while investigating white/gray matter connectivity, in both health and disease. PMID:24637718

Preventing Alcohol-Related Problems on Campus: Methods for Assessing Student Use of Alcohol and Other Drugs. A Guide for Program Coordinators.

ERIC Educational Resources Information Center

DeJong, William; Wechsler, Henry

Under the Drug-Free Schools and Campuses Act, institutions of higher education are required to review the effectiveness of their alcohol and drug prevention programs biannually. This guide offers a method for gathering and interpreting student survey data on alcohol-related problems based on the methodology of the College Alcohol Survey developed…

Alcohol and Drug Abuse Teaching Methodology Guide for Medical Faculty. Medicine 1. Health Professions Education Curriculum Resource Series.

ERIC Educational Resources Information Center

Hostetler, Jeptha R.

This guide, one of a series of publications written for medical faculty to use in designing substance abuse instruction, focuses on the teaching of alcohol and drug abuse intervention in medical and osteopathic schools. Following a brief introducton to the booklet, the career teacher program, which is supported by federal grants, is explained.…

[Goals, possibilities and limits of quality evaluation of guidelines. A background report on the user manual of the "Methodological Quality of Guidelines" check list].

PubMed

Helou, A; Ollenschläger, G

1998-06-01

Recently a German appraisal instrument for clinical guidelines was published that could be used by various parties in formal evaluation of guidelines. An user's guide to the appraisal instrument was designed that contains a detailed explanation for each question to ensure that the instrument is interpreted consistently. This paper describes the purposes, format and contents of the user's guide, and reviews the key factors influencing the validity of guidelines. Taking into account international experiences, the purposes, chances and methodological limitations of a prospective assessment of clinical practice guidelines are discussed.

AMEE Education Guide no. 29: evaluating educational programmes.

PubMed

Goldie, John

2006-05-01

Evaluation has become an applied science in its own right in the last 40 years. This guide reviews the history of programme evaluation through its initial concern with methodology, giving way to concern with the context of evaluation practice and into the challenge of fitting evaluation results into highly politicized and decentralized systems. It provides a framework for potential evaluators considering undertaking evaluation. The role of the evaluator; the ethics of evaluation; choosing the questions to be asked; evaluation design, including the dimensions of evaluation and the range of evaluation approaches available to guide evaluators; interpreting and disseminating the findings; and influencing decision making are covered.

The Effect of Chemical Disinfectants on the Color of a Porcelain Shade Guide

PubMed Central

ArRejaie, Aws S.

2014-01-01

Objective To evaluate the effect of long term utilization of chemical disinfectants on the color of porcelain shade guides. Methodology three chemical disinfectants were used in this study: Minuten spray, Lysol ICQuaternary Disinfectant Cleaner (QDC), and Lysol IC Ready to Use Disinfectant Cleaner (RDC). Simulation of disinfecting cycles for one year, two years, and three years were done on Vita 3D master shade guide. Color differences were determined by visual inspection and analyzing ΔE. Results ΔE values were significantly below the perceptible (ΔE=1) and the clinically acceptable (ΔE=3.7) thresholds. Conclusions Simulated utilization of Minuten Spray, Lysol IC (QDC), and Lysol (RDC) disinfectants for up to three years didn’t cause a clinically significant difference in the color of VITA Toothguide 3D-Master Shade Guide. PMID:25505865

Technical Support Document: The Development of the Advanced Energy Design Guide for Highway Lodging Buildings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jiang, Wei; Jarnagin, Ronald E.; Gowri, Krishnan

2008-09-30

This Technical Support Document (TSD) describes the process and methodology for development of the Advanced Energy Design Guide for Highway Lodgings (AEDG-HL or the Guide), a design guidance document intended to provide recommendations for achieving 30% energy savings in highway lodging properties over levels contained in ANSI/ASHRAE/IESNA Standard 90.1-1999, Energy Standard for Buildings Except Low-Rise Residential Buildings. The AEDG-HL is the fifth in a series of guides being developed by a partnership of organizations, including the American Society of Heating, Refrigerating and Air-Conditioning Engineers, Inc. (ASHRAE), the American Institute of Architects (AIA), the Illuminating Engineering Society of North America (IESNA),more » the United States Green Buildings Council (USGBC), and the U.S. Department of Energy (DOE).« less

ITS telecommunications : public or private? : a cost tradeoff methodology guide

DOT National Transportation Integrated Search

1996-12-16

This cost Tradeoff Assessment Methodology Report outlines generic steps and strategy for analyzing the costs of obtaining telecommunications capacity to meet the requirements of jurisdictional ITS programs. A special focus has been placed on analysis...

A methodology aimed at fostering and sustaining the development processes of an IE-based industry

NASA Astrophysics Data System (ADS)

Corallo, Angelo; Errico, Fabrizio; de Maggio, Marco; Giangreco, Enza

In the current competitive scenario, where business relationships are fundamental in building successful business models and inter/intra organizational business processes are progressively digitalized, an end-to-end methodology is required that is capable of guiding business networks through the Internetworked Enterprise (IE) paradigm: a new and innovative organizational model able to leverage Internet technologies to perform real-time coordination of intra and inter-firm activities, to create value by offering innovative and personalized products/services and reduce transaction costs. This chapter presents the TEKNE project Methodology of change that guides business networks, by means of a modular and flexible approach, towards the IE techno-organizational paradigm, taking into account the competitive environment of the network and how this environment influences its strategic, organizational and technological levels. Contingency, the business model, enterprise architecture and performance metrics are the key concepts that form the cornerstone of this methodological framework.

Development of Low-Cost Method for Fabrication of Metal Neutron Guides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Engelhaupt, Darell; Khaykovich, Boris; Romaine, Suzanne

Neutron scattering is one of the most useful methods of studying the structure and dynamics of matter. US DOE neutron scattering research facilities at Oak Ridge National Laboratory are among the World’s most advanced, providing researchers with unmatched capabilities for probing the structure and properties of materials, including engineering and biological systems. This task is to develop a lower cost process to optimize and produce the required neutron guides capable of efficiently delivering neutron beams for tens of meters between neutron moderators and instruments. Therefore, our effort is to improve the performance and lower the production cost of neutron guides.more » Our approach aims at improving guide quality while controlling their rising costs by adopting a novel electroforming replication approach to their fabrication. These guides will be especially advantageous when used near the neutron source since the radiation resistance of nickel is superior to glass. Additionally, we are depositing low-stress nickel from an extremely low impurity solution completely free of stress-reducing agents, which nominally contain and impart sulfur, carbon and other elements that potentially activate in the neutron environment. This is achieved by using a pulsed periodically reversed current methodology. The best guides quote waviness of 0.1 mrad. It is reasonable to prepare just one mandrel of about 0.5 m long, for production of tens of guide segments, saving both the cost and supply time of guides to neutron facilities. We estimate that we can fabricate a single mandrel for the current cost of an individual one-meter guide, but from this, we can produce tens of meters of guide very inexpensively without mandrel refurbishment. While a multilayer coating will add to the overall cost, we expect this will be less than that of commercially available guides today. Therefore, we will produce higher quality guides, which are less susceptible to radiation damage, at the lower cost than those available today.« less

Development of Low-Cost Method for Fabrication of Metal Neutron Guides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Engelhaupt, Darell; Khaykovich, Boris; Romaine, Suzanne

2017-12-19

Neutron scattering is one of the most useful methods of studying the structure and dynamics of matter. US DOE neutron scattering research facilities at Oak Ridge National Laboratory are among the World’s most advanced, providing researchers with unmatched capabilities for probing the structure and properties of materials, including engineering and biological systems. This task is to develop a lower cost process to optimize and produce the required neutron guides capable of efficiently delivering neutron beams for tens of meters between neutron moderators and instruments. Therefore, our effort is to improve the performance and lower the production cost of neutron guides.more » Our approach aims at improving guide quality while controlling their rising costs by adopting a novel electroforming replication approach to their fabrication. These guides will be especially advantageous when used near the neutron source since the radiation resistance of nickel is superior to glass. Additionally, we are depositing low-stress nickel from an extremely low impurity solution completely free of stress-reducing agents, which nominally contain and impart sulfur, carbon and other elements that potentially activate in the neutron environment. This is achieved by using a pulsed periodically reversed current methodology. The best guides quote waviness of 0.1 mrad. It is reasonable to prepare just one mandrel of about 0.5 m long, for production of tens of guide segments, saving both the cost and supply time of guides to neutron facilities. We estimate that we can fabricate a single mandrel for the current cost of an individual one-meter guide, but from this, we can produce tens of meters of guide very inexpensively without mandrel refurbishment. While a multilayer coating will add to the overall cost, we expect this will be less than that of commercially available guides today. Therefore, we will produce higher quality guides, which are less susceptible to radiation damage, at the lower cost than those available today.« less

Guide for certifying pressure vessels and systems

NASA Technical Reports Server (NTRS)

Lundy, Floyd; Krusa, Paul W.

1992-01-01

This guide is intended to provide methodology and describe the intent of the Pressure Vessel and System (PV/S) Certification program. It is not meant to be a mandated document, but is intended to transmit a basic understanding of the PV/S program, and include examples. After the reader has familiarized himself with this publication, he should have a basic understanding of how to go about developing a PV/S certification program.

Image-Guided Abdominal Surgery and Therapy Delivery

PubMed Central

Galloway, Robert L.; Herrell, S. Duke; Miga, Michael I.

2013-01-01

Image-Guided Surgery has become the standard of care in intracranial neurosurgery providing more exact resections while minimizing damage to healthy tissue. Moving that process to abdominal organs presents additional challenges in the form of image segmentation, image to physical space registration, organ motion and deformation. In this paper, we present methodologies and results for addressing these challenges in two specific organs: the liver and the kidney. PMID:25077012

50% Advanced Energy Design Guides: Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bonnema, E.; Leach, M.; Pless, S.

2012-07-01

This paper presents the process, methodology, and assumptions for the development of the 50% Energy Savings Advanced Energy Design Guides (AEDGs), a design guidance document that provides specific recommendations for achieving 50% energy savings above the requirements of ANSI/ASHRAE/IESNA Standard 90.1-2004 in four building types: (1) Small to medium office buildings, (2) K-12 school buildings, (3) Medium to big box retail buildings, (4) Large hospital buildings.

A cross impact methodology for the assessment of US telecommunications system with application to fiber optics development, volume 2

NASA Technical Reports Server (NTRS)

Martino, J. P.; Lenz, R. C., Jr.; Chen, K. L.; Kahut, P.; Sekely, R.; Weiler, J.

1979-01-01

The appendices for the cross impact methodology are presented. These include: user's guide, telecommunication events, cross impacts, projection of historical trends, and projection of trends in satellite communications.

Review of the transportation planning process in the Chicago metropolitan area

DOT National Transportation Integrated Search

2012-01-01

The purpose of this guide is to help agencies: Become familiar with the Costing Asset Protection for Transportation Agencies (CAPTA) Methodology. Learn how to use CAPTool to implement the CAPTA Methodology. Understand CAPTool results, and...

The Navigation Guide systematic review methodology: a rigorous and transparent method for translating environmental health science into better health outcomes.

PubMed

Woodruff, Tracey J; Sutton, Patrice

2014-10-01

Synthesizing what is known about the environmental drivers of health is instrumental to taking prevention-oriented action. Methods of research synthesis commonly used in environmental health lag behind systematic review methods developed in the clinical sciences over the past 20 years. We sought to develop a proof of concept of the "Navigation Guide," a systematic and transparent method of research synthesis in environmental health. The Navigation Guide methodology builds on best practices in research synthesis in evidence-based medicine and environmental health. Key points of departure from current methods of expert-based narrative review prevalent in environmental health include a prespecified protocol, standardized and transparent documentation including expert judgment, a comprehensive search strategy, assessment of "risk of bias," and separation of the science from values and preferences. Key points of departure from evidence-based medicine include assigning a "moderate" quality rating to human observational studies and combining diverse evidence streams. The Navigation Guide methodology is a systematic and rigorous approach to research synthesis that has been developed to reduce bias and maximize transparency in the evaluation of environmental health information. Although novel aspects of the method will require further development and validation, our findings demonstrated that improved methods of research synthesis under development at the National Toxicology Program and under consideration by the U.S. Environmental Protection Agency are fully achievable. The institutionalization of robust methods of systematic and transparent review would provide a concrete mechanism for linking science to timely action to prevent harm.

A land manager's guide to point counts of birds in the Southeast

USGS Publications Warehouse

Hamel, P.B.; Smith, W.P.; Twedt, D.J.; Woehr, J.R.; Morris, E.; Hamilton, R.B.; Cooper, R.J.

1996-01-01

Current widespread concern for the status of neotropical migratory birds has sparked interest in techniques for inventorying and monitoring populations of these and other birds in southeastern forest habitats. The present guide gives detailed instructions for conducting point counts of birds. It further presents a detailed methodology for the design and conduct of inventorial and monitoring surveys based on point counts, including discussion of sample size determination, distribution of counts among habitats, cooperation among neighboring land managers, vegetation sampling, standard data format, and other topics. Appendices provide additional information, making this guide a stand-alone text for managers interested in developing inventories of bird populations on their lands.

L'E.A.P. ou l'anglais enseigne dans les etudes superieures. Un guide pour le debutant (E.A.P. or English for Academic Purposes: A Guide for the Beginner).

ERIC Educational Resources Information Center

Roe, Peter J.

1981-01-01

Addresses those readers who are not familiar with EAP, offering an introductory discussion of its objectives and methods, in two parts. Devotes the first part to the needs that justify an EAP approach, and the second to its methodology, with particular attention to interdisciplinary, task-oriented instruction. Societe Nouvelle Didier Erudition, 40…

Jobs and Economic Development Impact (JEDI) Model: Offshore Wind User Reference Guide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lantz, E.; Goldberg, M.; Keyser, D.

2013-06-01

The Offshore Wind Jobs and Economic Development Impact (JEDI) model, developed by NREL and MRG & Associates, is a spreadsheet based input-output tool. JEDI is meant to be a user friendly and transparent tool to estimate potential economic impacts supported by the development and operation of offshore wind projects. This guide describes how to use the model as well as technical information such as methodology, limitations, and data sources.

An Agile Constructionist Mentoring Methodology for Software Projects in the High School

ERIC Educational Resources Information Center

Meerbaum-Salant, Orni; Hazzan, Orit

2010-01-01

This article describes the construction process and evaluation of the Agile Constructionist Mentoring Methodology (ACMM), a mentoring method for guiding software development projects in the high school. The need for such a methodology has arisen due to the complexity of mentoring software project development in the high school. We introduce the…

Guided ultrasonic wave beam skew in silicon wafers

NASA Astrophysics Data System (ADS)

Pizzolato, Marco; Masserey, Bernard; Robyr, Jean-Luc; Fromme, Paul

2018-04-01

In the photovoltaic industry, monocrystalline silicon wafers are employed for solar cells with high conversion efficiency. Micro-cracks induced by the cutting process in the thin wafers can lead to brittle wafer fracture. Guided ultrasonic waves would offer an efficient methodology for the in-process non-destructive testing of wafers to assess micro-crack density. The material anisotropy of the monocrystalline silicon leads to variations of the guided wave characteristics, depending on the propagation direction relative to the crystal orientation. Selective guided ultrasonic wave excitation was achieved using a contact piezoelectric transducer with custom-made wedges for the A0 and S0 Lamb wave modes and a transducer holder to achieve controlled contact pressure and orientation. The out-of-plane component of the guided wave propagation was measured using a non-contact laser interferometer. The phase slowness (velocity) of the two fundamental Lamb wave modes was measured experimentally for varying propagation directions relative to the crystal orientation and found to match theoretical predictions. Significant wave beam skew was observed experimentally, especially for the S0 mode, and investigated from 3D finite element simulations. Good agreement was found with the theoretical predictions based on nominal material properties of the silicon wafer. The important contribution of guided wave beam skewing effects for the non-destructive testing of silicon wafers was demonstrated.

The Navigation Guide—Evidence-Based Medicine Meets Environmental Health: Systematic Review of Human Evidence for PFOA Effects on Fetal Growth

PubMed Central

Sutton, Patrice; Atchley, Dylan S.; Koustas, Erica; Lam, Juleen; Sen, Saunak; Robinson, Karen A.; Axelrad, Daniel A.; Woodruff, Tracey J.

2014-01-01

Background: The Navigation Guide methodology was developed to meet the need for a robust method of systematic and transparent research synthesis in environmental health science. We conducted a case study systematic review to support proof of concept of the method. Objective: We applied the Navigation Guide systematic review methodology to determine whether developmental exposure to perfluorooctanoic acid (PFOA) affects fetal growth in humans. Methods: We applied the first 3 steps of the Navigation Guide methodology to human epidemiological data: 1) specify the study question, 2) select the evidence, and 3) rate the quality and strength of the evidence. We developed a protocol, conducted a comprehensive search of the literature, and identified relevant studies using prespecified criteria. We evaluated each study for risk of bias and conducted meta-analyses on a subset of studies. We rated quality and strength of the entire body of human evidence. Results: We identified 18 human studies that met our inclusion criteria, and 9 of these were combined through meta-analysis. Through meta-analysis, we estimated that a 1-ng/mL increase in serum or plasma PFOA was associated with a –18.9 g (95% CI: –29.8, –7.9) difference in birth weight. We concluded that the risk of bias across studies was low, and we assigned a “moderate” quality rating to the overall body of human evidence. Conclusion: On the basis of this first application of the Navigation Guide systematic review methodology, we concluded that there is “sufficient” human evidence that developmental exposure to PFOA reduces fetal growth. Citation: Johnson PI, Sutton P, Atchley DS, Koustas E, Lam J, Sen S, Robinson KA, Axelrad DA, Woodruff TJ. 2014. The Navigation Guide—evidence-based medicine meets environmental health: systematic review of human evidence for PFOA effects on fetal growth. Environ Health Perspect 122:1028–1039; http://dx.doi.org/10.1289/ehp.1307893 PMID:24968388

Towards improved NDE and SHM methodologies incorporating nonlinear structural features

NASA Astrophysics Data System (ADS)

Chillara, Vamshi Krishna

Ultrasound is widely employed in Nondestructive Evaluation (NDE) and Structural Health Monitoring (SHM) applications to detect and characterize damage/defects in materials. In particular, ultrasonic guided waves are considered a foremost candidate for in-situ monitoring applications. Conventional ultrasonic techniques rely on changes/discontinuities in linear elastic material properties, namely the Young's modulus and shear modulus to detect damage. On the other hand, nonlinear ultrasonic techniques that rely on micro-scale nonlinear material/structural behavior are proven to be sensitive to damage induced microstructural changes that precede macro-scale damage and are hence capable of early damage detection. The goal of this thesis is to investigate the capabilities of nonlinear guided waves --- a fusion of nonlinear ultrasonic techniques with the guided wave methodologies for early damage detection. To that end, the thesis focuses on two important aspects of the problem: 1. Wavemechanics - deals with ultrasonic guided wave propagation in nonlinear waveguides; 2. Micromechanics - deals with correlating ultrasonic response with micro-scale nonlinear material behavior. For the development of efficient NDE and SHM methodologies that incorporate nonlinear structural features, a detailed understanding of the above aspects is indispensable. In this thesis, the wavemechanics aspect of the problem is dealt with from both theoretical and numerical standpoints. A generalized theoretical framework is developed to study higher harmonic guided waves in plates. This was employed to study second harmonic guided waves in pipes using a large-radius asymptotic approximation. Second harmonic guided waves in plates are studied from a numerical standpoint. Theoretical predictions are validated and some key aspects of higher harmonic generation in waveguides are outlined. Finally, second harmonic guided waves in plates with inhomogeneous and localized nonlinearities are studied and some important aspects of guided wave mode selection are addressed. The other part of the work focused on developing a micromechanics based understanding of ultrasonic higher harmonic generation. Three important aspects of micro-scale material behavior, namely tension-compression asymmetry, shearnormal coupling and deformation induced asymmetry are identified and their role in ultrasonic higher harmonic generation is discussed. Tension-compression asymmetry is identified to cause second (even) harmonic generation in materials. Then, shearnormal coupling is identified to cause generation of secondary waves of different polarity than the primary waves. In addition, deformation induced anisotropy due to the presence of residual stress/strain and its contribution to ultrasonic higher harmonic generation is qualitatively discussed. Also, the tension-compression asymmetry in the material is quantified using an energy based measure. The above measure is employed to develop a homogenization based approach amenable to multi-scale analysis to correlate microstructure with ultrasonic higher harmonic generation. Finally, experimental investigations concerning third harmonic SH wave generation in plates are carried out and the effect of load and temperature changes on nonlinear ultrasonic measurements are discussed in the context of SHM. It was found that while nonlinear ultrasound is sensitive to micro-scale damage, the relative nonlinearity parameter may not always be the best measure to quantify the nonlinearity as it is subject to spurious effects from changes in environmental factors such as loads and temperature.

Future Field Programmable Gate Array (FPGA) Design Methodologies and Tool Flows

DTIC Science & Technology

2008-07-01

a) that the results are accepted by users, vendors, … and (b) that they can quantitatively explain HPC rules of thumb such as: “OpenMP is easier...in productivity that were demonstrated by traditional software systems. Using advances in software productivity as a guide , we have identified three...of this study we developed a productivity model to guide our investigation (14). Models have limitations and the model we propose is no exception

Integration of 3D anatomical data obtained by CT imaging and 3D optical scanning for computer aided implant surgery

PubMed Central

2011-01-01

Background A precise placement of dental implants is a crucial step to optimize both prosthetic aspects and functional constraints. In this context, the use of virtual guiding systems has been recognized as a fundamental tool to control the ideal implant position. In particular, complex periodontal surgeries can be performed using preoperative planning based on CT data. The critical point of the procedure relies on the lack of accuracy in transferring CT planning information to surgical field through custom-made stereo-lithographic surgical guides. Methods In this work, a novel methodology is proposed for monitoring loss of accuracy in transferring CT dental information into periodontal surgical field. The methodology is based on integrating 3D data of anatomical (impression and cast) and preoperative (radiographic template) models, obtained by both CT and optical scanning processes. Results A clinical case, relative to a fully edentulous jaw patient, has been used as test case to assess the accuracy of the various steps concurring in manufacturing surgical guides. In particular, a surgical guide has been designed to place implants in the bone structure of the patient. The analysis of the results has allowed the clinician to monitor all the errors, which have been occurring step by step manufacturing the physical templates. Conclusions The use of an optical scanner, which has a higher resolution and accuracy than CT scanning, has demonstrated to be a valid support to control the precision of the various physical models adopted and to point out possible error sources. A case study regarding a fully edentulous patient has confirmed the feasibility of the proposed methodology. PMID:21338504

MRI-guided robotics at the U of Houston: evolving methodologies for interventions and surgeries.

PubMed

Tsekos, Nikolaos V

2009-01-01

Currently, we witness the rapid evolution of minimally invasive surgeries (MIS) and image guided interventions (IGI) for offering improved patient management and cost effectiveness. It is well recognized that sustaining and expand this paradigm shift would require new computational methodology that integrates sensing with multimodal imaging, actively controlled robotic manipulators, the patient and the operator. Such approach would include (1) assessing in real-time tissue deformation secondary to the procedure and physiologic motion, (2) monitoring the tool(s) in 3D, and (3) on-the-fly update information about the pathophysiology of the targeted tissue. With those capabilities, real time image guidance may facilitate a paradigm shift and methodological leap from "keyhole" visualization (i.e. endoscopy or laparoscopy) to one that uses a volumetric and informational rich perception of the Area of Operation (AoO). This capability may eventually enable a wider range and level of complexity IGI and MIS.

Indigenous Storytelling and Participatory Action Research

PubMed Central

2015-01-01

Storytelling, in its various forms, has often been described as a practice with great emancipatory potential. In turn, Indigenous knowledge shows great promise in guiding a participatory action research (PAR) methodology. Yet these two approaches are rarely discussed in relation to one another, nor, has much been written in terms of how these two approaches may work synergistically toward a decolonizing research approach. In this article, I report on a community-driven knowledge translation activity, the Peoples’ International Health Tribunal, as an exemplar of how narrative and PAR approaches, guided by local Indigenous knowledge, have great potential to build methodologically and ethically robust research processes. Implications for building globally relevant research alliances and scholarship are further discussed, particularly in relation to working with Indigenous communities. PMID:28462305

Impact of the 1980 BEIR-III report on low-level radiation risk assessment, radiation protection guides, and public health policy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fabrikant, J.I.

1981-06-01

The author deals with the scientific basis for establishing appropriate radiation protection guides, and this effect on evaluation of societal activities concerned with the health effects in human populations exposed to low-level radiation. Methodology is discussed for estimating risks of radio-induced cancer and genetically related ill-health in man, the sources of data, the dose-response models used, and the precision ascribed to the process. (PSB)

Grounded Theory: A practical guide for management, business and market researchers Christina Goulding Grounded Theory: A practical guide for management, business and market researchers Sage Publications No of pages: 186 £18.99 0761966838 0761966838 [Formula: see text].

PubMed

Woods, Leslie

2003-10-01

Much has been written about the grounded theory approach to qualitative research, however the number of books devoted solely to this methodology remains relatively few. Therefore, any new book dedicated to the subject is always likely to attract attention - especially given the increasing popularity of grounded theory in healthcare research.

Methodology for Assessing Disruptions (MAD) Game Part I: Report and Analysis

DTIC Science & Technology

2012-12-01

élaborées dans le Guide de planification fonctionnelle du groupe du SMA(S& T ). Le présent mémorandum technique est principalement destiné au Bureau du...le Guide de planification fonctionnelle du groupe du SMA(S& T ). Le présent mémorandum technique est principalement destiné au Bureau du scientifique en...2010 2012-009 Principal Author Original signed by G . Adlakha-Hutcheon, M. Hazen, P. Hubbard, S. McLelland, K. Sprague G . Adlakha

Jobs and Economic Development Impact (JEDI) User Reference Guide: Fast Pyrolysis Biorefinery Model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Yimin; Goldberg, Marshall

2015-02-01

This guide -- the JEDI Fast Pyrolysis Biorefinery Model User Reference Guide -- was developed to assist users in operating and understanding the JEDI Fast Pyrolysis Biorefinery Model. The guide provides information on the model's underlying methodology, as well as the parameters and data sources used to develop the cost data utilized in the model. This guide also provides basic instruction on model add-in features and a discussion of how the results should be interpreted. Based on project-specific inputs from the user, the JEDI Fast Pyrolysis Biorefinery Model estimates local (e.g., county- or state-level) job creation, earnings, and output frommore » total economic activity for a given fast pyrolysis biorefinery. These estimates include the direct, indirect and induced economic impacts to the local economy associated with the construction and operation phases of biorefinery projects.Local revenue and supply chain impacts as well as induced impacts are estimated using economic multipliers derived from the IMPLAN software program. By determining the local economic impacts and job creation for a proposed biorefinery, the JEDI Fast Pyrolysis Biorefinery Model can be used to field questions about the added value biorefineries might bring to a local community.« less

The Experience of Being a Guide Dog Puppy Raiser Volunteer: A Longitudinal Qualitative Collective Case Study

PubMed Central

Chur-Hansen, Anna; Werner, Lucy-Kate; McGuiness, Clare E.; Hazel, Susan

2014-01-01

Simple Summary Guide dogs are important service animals. They cannot be trained without the input of volunteer puppy raisers, who serve as custodians for the animals for around 12 months. To date very little research has considered the experience of being a guide dog puppy raiser, including the costs and benefits to psychological, physical and social health. In this study one litter of puppies and their raisers were followed from before the animal arrived until one year had passed. Overall, less positive experiences were reported than more negative ones. This has implications for the organisations that seek volunteers to raise service animals. Abstract There are no published studies that consider the experiences of guide dog puppy raisers. As these people are volunteers, their continued willingness to participate in the training of dogs for assisting the vision impaired and blind is essential for the viability of guide dog schools around the world. Using a qualitative, longitudinal methodology, data were collected from nine guide dog puppy raisers at four time points: before receiving the puppy, one week, then three months after the puppy arrived, and 13 months after the puppy arrived (at which time all puppies had left the raisers). Participants reported more challenges than benefits in raising the puppies. Volunteering to be a guide dog puppy raiser may not be the pleasant experience that is anticipated when community members first offer their services. Understanding what it is like to be a puppy raiser and working towards ways in which to address problems is essential, given that, without volunteers to train and care for puppies, vision impaired and blind people would not have access to guide dogs. PMID:26479133

The Oratorical Scientist: A Guide for Speechcraft and Presentation for Scientists

NASA Astrophysics Data System (ADS)

Lau, G. E.

2015-12-01

Public speaking organizations are highly valuable for individuals seeking to improve their skills in speech development and delivery. The methodology of such groups usually focuses on repetitive, guided practice. Toastmasters International, for instance, uses a curriculum based on topical manuals that guide their members through some number of prepared speeches with specific goals for each speech. I have similarly developed a public speaking manual for scientists with the intention of guiding scientists through the development and presentation of speeches that will help them hone their abilities as public speakers. I call this guide The Oratorical Scientist. The Oratorical Scientist will be a free, digital publication that is meant to guide scientists through five specific types of speech that the scientist may be called upon to deliver during their career. These five speeches are: The Coffee Talk, The Educational Talk, Research Talks for General Science Audiences, Research Talks for Specific Subdiscipline Audiences, and Taking the Big Stage (talks for public engagement). Each section of the manual focuses on speech development, rehearsal, and presentation for each of these specific types of speech. The curriculum was developed primarily from my personal experiences in public engagement. Individuals who use the manual may deliver their prepared speeches to groups of their peers (e.g. within their research group) or through video sharing websites like Youtube and Vimeo. Speeches that are broadcast online can then be followed and shared through social media networks (e.g. #OratoricalScientist), allowing a larger audience to evaluate the speech and to provide criticism. I will present The Oratorical Scientist, a guide for scientists to become better public speakers. The process of guided repetitive practice of scientific talks will improve the speaking capabilities of scientists, in turn benefitting science communication and public engagement.

Using Constructivist Case Study Methodology to Understand Community Development Processes: Proposed Methodological Questions to Guide the Research Process

ERIC Educational Resources Information Center

Lauckner, Heidi; Paterson, Margo; Krupa, Terry

2012-01-01

Often, research projects are presented as final products with the methodologies cleanly outlined and little attention paid to the decision-making processes that led to the chosen approach. Limited attention paid to these decision-making processes perpetuates a sense of mystery about qualitative approaches, particularly for new researchers who will…

The Atomic Intrinsic Integration Approach: A Structured Methodology for the Design of Games for the Conceptual Understanding of Physics

ERIC Educational Resources Information Center

Echeverria, Alejandro; Barrios, Enrique; Nussbaum, Miguel; Amestica, Matias; Leclerc, Sandra

2012-01-01

Computer simulations combined with games have been successfully used to teach conceptual physics. However, there is no clear methodology for guiding the design of these types of games. To remedy this, we propose a structured methodology for the design of conceptual physics games that explicitly integrates the principles of the intrinsic…

The Interpretative Phenomenological Analysis (IPA): A Guide to a Good Qualitative Research Approach

ERIC Educational Resources Information Center

Alase, Abayomi

2017-01-01

As a research methodology, qualitative research method infuses an added advantage to the exploratory capability that researchers need to explore and investigate their research studies. Qualitative methodology allows researchers to advance and apply their interpersonal and subjectivity skills to their research exploratory processes. However, in a…

Delphi Research Methodology Applied to Place-Based Watershed Education

ERIC Educational Resources Information Center

Vallor, Rosanna R.; Yates, Kimberly A.; Brody, Michael

2016-01-01

This research focuses on the results of the Flathead Watershed Delphi survey, a consensus-building methodology used to establish foundational knowledge, skills and dispositions for the Flathead Watershed Educators Guide, a place-based watershed curriculum for middle school grades based on the Flathead Watershed Sourcebook. Survey participants (n =…

Research Methods Tutorial

NASA Technical Reports Server (NTRS)

Aguilera, Frank J.

2015-01-01

A guiding principle for conducting research in technology, science, and engineering, leading to innovation is based on our use of research methodology (both qualitative and qualitative). A brief review of research methodology will be presented with an overview of NASA process in developing aeronautics technologies and other things to consider in research including what is innovation.

Research Methods Tutorial

NASA Technical Reports Server (NTRS)

Aguilera, Frank J.

2015-01-01

A guiding principle for conducting research in technology, science, and engineering, leading to innovation is based on our use of research methodology (both qualitative and quantitative). A brief review of research methodology will be presented with an overview of NASA process in developing aeronautics technologies and other things to consider in research including what is innovation.

Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage

PubMed Central

Josephs, Eric A.; Kocak, D. Dewran; Fitzgibbon, Christopher J.; McMenemy, Joshua; Gersbach, Charles A.; Marszalek, Piotr E.

2015-01-01

CRISPR-associated endonuclease Cas9 cuts DNA at variable target sites designated by a Cas9-bound RNA molecule. Cas9's ability to be directed by single ‘guide RNA’ molecules to target nearly any sequence has been recently exploited for a number of emerging biological and medical applications. Therefore, understanding the nature of Cas9's off-target activity is of paramount importance for its practical use. Using atomic force microscopy (AFM), we directly resolve individual Cas9 and nuclease-inactive dCas9 proteins as they bind along engineered DNA substrates. High-resolution imaging allows us to determine their relative propensities to bind with different guide RNA variants to targeted or off-target sequences. Mapping the structural properties of Cas9 and dCas9 to their respective binding sites reveals a progressive conformational transformation at DNA sites with increasing sequence similarity to its target. With kinetic Monte Carlo (KMC) simulations, these results provide evidence of a ‘conformational gating’ mechanism driven by the interactions between the guide RNA and the 14th–17th nucleotide region of the targeted DNA, the stabilities of which we find correlate significantly with reported off-target cleavage rates. KMC simulations also reveal potential methodologies to engineer guide RNA sequences with improved specificity by considering the invasion of guide RNAs into targeted DNA duplex. PMID:26384421

Ethnography in qualitative educational research: AMEE Guide No. 80.

PubMed

Reeves, Scott; Peller, Jennifer; Goldman, Joanne; Kitto, Simon

2013-08-01

Ethnography is a type of qualitative research that gathers observations, interviews and documentary data to produce detailed and comprehensive accounts of different social phenomena. The use of ethnographic research in medical education has produced a number of insightful accounts into its role, functions and difficulties in the preparation of medical students for clinical practice. This AMEE Guide offers an introduction to ethnography - its history, its differing forms, its role in medical education and its practical application. Specifically, the Guide initially outlines the main characteristics of ethnography: describing its origins, outlining its varying forms and discussing its use of theory. It also explores the role, contribution and limitations of ethnographic work undertaken in a medical education context. In addition, the Guide goes on to offer a range of ideas, methods, tools and techniques needed to undertake an ethnographic study. In doing so it discusses its conceptual, methodological, ethical and practice challenges (e.g. demands of recording the complexity of social action, the unpredictability of data collection activities). Finally, the Guide provides a series of final thoughts and ideas for future engagement with ethnography in medical education. This Guide is aimed for those interested in understanding ethnography to develop their evaluative skills when reading such work. It is also aimed at those interested in considering the use of ethnographic methods in their own research work.

Integrated HPTLC-based Methodology for the Tracing of Bioactive Compounds in Herbal Extracts Employing Multivariate Chemometrics. A Case Study on Morus alba.

PubMed

Chaita, Eliza; Gikas, Evagelos; Aligiannis, Nektarios

2017-03-01

In drug discovery, bioassay-guided isolation is a well-established procedure, and still the basic approach for the discovery of natural products with desired biological properties. However, in these procedures, the most laborious and time-consuming step is the isolation of the bioactive constituents. A prior identification of the compounds that contribute to the demonstrated activity of the fractions would enable the selection of proper chromatographic techniques and lead to targeted isolation. The development of an integrated HPTLC-based methodology for the rapid tracing of the bioactive compounds during bioassay-guided processes, using multivariate statistics. Materials and Methods - The methanol extract of Morus alba was fractionated employing CPC. Subsequently, fractions were assayed for tyrosinase inhibition and analyzed with HPTLC. PLS-R algorithm was performed in order to correlate the analytical data with the biological response of the fractions and identify the compounds with the highest contribution. Two methodologies were developed for the generation of the dataset; one based on manual peak picking and the second based on chromatogram binning. Results and Discussion - Both methodologies afforded comparable results and were able to trace the bioactive constituents (e.g. oxyresveratrol, trans-dihydromorin, 2,4,3'-trihydroxydihydrostilbene). The suggested compounds were compared in terms of R f values and UV spectra with compounds isolated from M. alba using typical bioassay-guided process. Chemometric tools supported the development of a novel HPTLC-based methodology for the tracing of tyrosinase inhibitors in M. alba extract. All steps of the experimental procedure implemented techniques that afford essential key elements for application in high-throughput screening procedures for drug discovery purposes. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

An Approach for Preoperative Planning and Performance of MR-guided Interventions Demonstrated With a Manual Manipulator in a 1.5T MRI Scanner

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seimenis, Ioannis; Tsekos, Nikolaos V.; Keroglou, Christoforos

2012-04-15

Purpose: The aim of this work was to develop and test a general methodology for the planning and performance of robot-assisted, MR-guided interventions. This methodology also includes the employment of software tools with appropriately tailored routines to effectively exploit the capabilities of MRI and address the relevant spatial limitations. Methods: The described methodology consists of: (1) patient-customized feasibility study that focuses on the geometric limitations imposed by the gantry, the robotic hardware, and interventional tools, as well as the patient; (2) stereotactic preoperative planning for initial positioning of the manipulator and alignment of its end-effector with a selected target; andmore » (3) real-time, intraoperative tool tracking and monitoring of the actual intervention execution. Testing was performed inside a standard 1.5T MRI scanner in which the MR-compatible manipulator is deployed to provide the required access. Results: A volunteer imaging study demonstrates the application of the feasibility stage. A phantom study on needle targeting is also presented, demonstrating the applicability and effectiveness of the proposed preoperative and intraoperative stages of the methodology. For this purpose, a manually actuated, MR-compatible robotic manipulation system was used to accurately acquire a prescribed target through alternative approaching paths. Conclusions: The methodology presented and experimentally examined allows the effective performance of MR-guided interventions. It is suitable for, but not restricted to, needle-targeting applications assisted by a robotic manipulation system, which can be deployed inside a cylindrical scanner to provide the required access to the patient facilitating real-time guidance and monitoring.« less

Toward an Application Guide for Safety Integrity Level Allocation in Railway Systems.

PubMed

Ouedraogo, Kiswendsida Abel; Beugin, Julie; El-Koursi, El-Miloudi; Clarhaut, Joffrey; Renaux, Dominique; Lisiecki, Frederic

2018-02-02

The work in the article presents the development of an application guide based on feedback and comments stemming from various railway actors on their practices of SIL allocation to railway safety-related functions. The initial generic methodology for SIL allocation has been updated to be applied to railway rolling stock safety-related functions in order to solve the SIL concept application issues. Various actors dealing with railway SIL allocation problems are the intended target of the methodology; its principles will be summarized in this article with a focus on modifications and precisions made in order to establish a practical guide for railway safety authorities. The methodology is based on the flowchart formalism used in CSM (common safety method) European regulation. It starts with the use of quantitative safety requirements, particularly tolerable hazard rates (THR). THR apportioning rules are applied. On the one hand, the rules are related to classical logical combinations of safety-related functions preventing hazard occurrence. On the other hand, to take into account technical conditions (last safety weak link, functional dependencies, technological complexity, etc.), specific rules implicitly used in existing practices are defined for readjusting some THR values. SIL allocation process based on apportioned and validated THR values is finally illustrated through the example of "emergency brake" subsystems. Some specific SIL allocation rules are also defined and illustrated. © 2018 Society for Risk Analysis.

Transmission Line Jobs and Economic Development Impact (JEDI) Model User Reference Guide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldberg, M.; Keyser, D.

The Jobs and Economic Development Impact (JEDI) models, developed through the National Renewable Energy Laboratory (NREL), are freely available, user-friendly tools that estimate the potential economic impacts of constructing and operating power generation projects for a range of conventional and renewable energy technologies. The Transmission Line JEDI model can be used to field questions about the economic impacts of transmission lines in a given state, region, or local community. This Transmission Line JEDI User Reference Guide was developed to provide basic instruction on operating the model and understanding the results. This guide also provides information on the model's underlying methodology,more » as well as the parameters and references used to develop the cost data contained in the model.« less

Investigation of guided waves propagation in pipe buried in sand

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leinov, Eli; Cawley, Peter; Lowe, Michael J.S.

The inspection of pipelines by guided wave testing is a well-established method for the detection of corrosion defects in pipelines, and is currently used routinely in a variety of industries, e.g. petrochemical and energy. When the method is applied to pipes buried in soil, test ranges tend to be significantly compromised because of attenuation of the waves caused by energy radiating into the soil. Moreover, the variability of soil conditions dictates different attenuation characteristics, which in-turn results in different, unpredictable, test ranges. We investigate experimentally the propagation and attenuation characteristics of guided waves in pipes buried in fine sand usingmore » a well characterized full scale experimental apparatus. The apparatus consists of an 8 inch-diameter, 5.6-meters long steel pipe embedded over 3 meters of its length in a rectangular container filled with fine sand, and an air-bladder for the application of overburden pressure. Longitudinal and torsional guided waves are excited in the pipe and recorded using a transducer ring (Guided Ultrasonics Ltd). Acoustic properties of the sand are measured independently in-situ and used to make model predictions of wave behavior in the buried pipe. We present the methodology and the systematic measurements of the guided waves under a range of conditions, including loose and compacted sand. It is found that the application of overburden pressure modifies the compaction of the sand and increases the attenuation, and that the measurement of the acoustic properties of sand allows model prediction of the attenuation of guided waves in buried pipes with a high level of confidence.« less

Multi-layered fabrication of large area PDMS flexible optical light guide sheets

NASA Astrophysics Data System (ADS)

Green, Robert; Knopf, George K.; Bordatchev, Evgueni V.

2017-02-01

Large area polydimethylsiloxane (PDMS) flexible optical light guide sheets can be used to create a variety of passive light harvesting and illumination systems for wearable technology, advanced indoor lighting, non-planar solar light collectors, customized signature lighting, and enhanced safety illumination for motorized vehicles. These thin optically transparent micro-patterned polymer sheets can be draped over a flat or arbitrarily curved surface. The light guiding behavior of the optical light guides depends on the geometry and spatial distribution of micro-optical structures, thickness and shape of the flexible sheet, refractive indices of the constituent layers, and the wavelength of the incident light. A scalable fabrication method that combines soft-lithography, closed thin cavity molding, partial curing, and centrifugal casting is described in this paper for building thin large area multi-layered PDMS optical light guide sheets. The proposed fabrication methodology enables the of internal micro-optical structures (MOSs) in the monolithic PDMS light guide by building the optical system layer-by-layer. Each PDMS layer in the optical light guide can have the similar, or a slightly different, indices of refraction that permit total internal reflection within the optical sheet. The individual molded layers may also be defect free or micro-patterned with microlens or reflecting micro-features. In addition, the bond between adjacent layers is ensured because each layer is only partially cured before the next functional layer is added. To illustrate the scalable build-by-layers fabrication method a three-layer mechanically flexible illuminator with an embedded LED strip is constructed and demonstrated.

Indigenous Storytelling and Participatory Action Research: Allies Toward Decolonization? Reflections From the Peoples' International Health Tribunal.

PubMed

Caxaj, C Susana

2015-01-01

Storytelling, in its various forms, has often been described as a practice with great emancipatory potential. In turn, Indigenous knowledge shows great promise in guiding a participatory action research (PAR) methodology. Yet these two approaches are rarely discussed in relation to one another, nor, has much been written in terms of how these two approaches may work synergistically toward a decolonizing research approach. In this article, I report on a community-driven knowledge translation activity, the Peoples' International Health Tribunal, as an exemplar of how narrative and PAR approaches, guided by local Indigenous knowledge, have great potential to build methodologically and ethically robust research processes. Implications for building globally relevant research alliances and scholarship are further discussed, particularly in relation to working with Indigenous communities.

The Literature Review of Analytical Support to Defence Transformation: Lessons Learned from Turkish Air Force Transformation Activities

DTIC Science & Technology

2010-04-01

available [11]. Additionally, Table-3 is a guide for DMAIC methodology including 29 different methods [12]. RTO-MP-SAS-081 6 - 4 NATO UNCLASSIFIED NATO...Table 3: DMAIC Methodology (5-Phase Methodology). Define Measure Analyze Improve Control Project Charter Prioritization Matrix 5 Whys Analysis...Methodology Scope [13] DMAIC PDCA Develop performance priorities This is a preliminary stage that precedes specific improvement projects, and the aim

Practical methodological guide for hydrometric inter-laboratory organisation

NASA Astrophysics Data System (ADS)

Besson, David; Bertrand, Xavier

2015-04-01

Discharge measurements performed by the French governmental hydrometer team feed a national database. This data is available for general river flows knowkedge, flood forecasting, low water survey, statistical calculations flow, control flow regulatory and many other uses. Regularly checking the measurements quality and better quantifying its accuracy is therefore an absolute need. The practice of inter-laboratory comparison in hydrometry particularly developed during the last decade. Indeed, discharge measurement can not easily be linked to a standard. Therefore, on-site measurement accuracy control is very difficult. Inter-laboratory comparison is thus a practical solution to this issue. However, it needs some regulations in order to ease its practice and legitimize its results. To do so, the French government hydrometrics teams produced a practical methodological guide for hydrometric inter-laboratory organisation in destination of hydrometers community in view of ensure the harmonization of inter-laboratory comparison practices for different materials (ADCP, current meter on wadind rod or gauging van, tracer dilution, surface speed) and flow range (flood, low water). Ensure the results formalization and banking. The realisation of this practice guide is grounded on the experience of the governmental teams & their partners (or fellows), following existing approaches (Doppler group especially). The guide is designated to validate compliance measures and identify outliers : Hardware, methodological, environmental, or human. Inter-laboratory comparison provides the means to verify the compliance of the instruments (devices + methods + operators) and provides methods to determine an experimental uncertainty of the tested measurement method which is valid only for the site and the measurement conditions but does not address the calibration or periodic monitoring of the few materials. After some conceptual definitions, the guide describes the different stages of an inter-comparison campaign: the campaing creation: targets, participants ( instruments type and number) and site preparation of test protocols and schedule; the campaign set-up (organization): invitation and pre-information of the participants, logistics, field preparation; the campaign conduct: participants reception and information, sequences of tests, results analysis and communication, balance sheet; post-campaign work: further analysis, dissemination and periodic verification of the instruments. This guide is associated with measurement instruments forms, reminding their limits and conditions for use, land forms, used to record all the necessary information during the inter-comparison campaign (site description and measurement conditions, equipment and its settings, and the set of measurements or intermediate calculations to the final results) as well as a calculation tool and banking measures and results.

Implementation of a documentation model comprising nursing terminologies--theoretical and methodological issues.

PubMed

von Krogh, Gunn; Nåden, Dagfinn

2008-04-01

To describe and discuss theoretical and methodological issues of implementation of a nursing services documentation model comprising NANDA nursing diagnoses, Nursing Intervention Classification and Nursing Outcome Classification terminologies. The model is developed for electronic patient record and was implemented in a psychiatric hospital on an organizational level and on five test wards in 2001-2005. The theory of Rogers guided the process of innovation, whereas the implementation procedure of McCloskey and Bulecheck combined with adult learning principals guided the test site implementation. The test wards managed in different degrees to adopt the model. Two wards succeeded fully, including a ward with high percentage of staff with interdisciplinary background. Better planning regarding the impact of the organization's innovative aptitude, the innovation strategies and the use of differentiated methods regarding the clinician's individual premises for learning nursing terminologies might have enhanced the adoption to the model. To better understand the nature of barriers and the importance of careful planning regarding the implementation of electronic patient record elements in nursing care services, focusing on nursing terminologies. Further to indicate how a theory and specific procedure can be used to guide the process of implementation throughout the different levels of management.

Heterogeneous Effects in Education: The Promise and Challenge of Incorporating Intersectionality into Quantitative Methodological Approaches

ERIC Educational Resources Information Center

Schudde, Lauren

2018-01-01

To date, the theory of intersectionality has largely guided qualitative efforts in social science and education research. Translating the construct to new methodological approaches is inherently complex and challenging, but offers the possibility of breaking down silos that keep education researchers with similar interests--but different…

Reflective Pedagogy: The Integration of Methodology and Subject-Matter Content in a Graduate-Level Course

ERIC Educational Resources Information Center

Jakeman, Rick C.; Henderson, Markesha M.; Howard, Lionel C.

2017-01-01

This article presents a critical reflection on how we, instructors of a graduate-level course in higher education administration, sought to integrate theoretical and subject-matter content and research methodology. Our reflection, guided by autoethnography and teacher reflection, challenged both our assumptions about curriculum design and our…

The Interplay between Methodologies, Tasks and Visualisation Formats in the Study of Visual Expertise

ERIC Educational Resources Information Center

Boucheix, Jean-Michel

2017-01-01

This article introduces this special issue of "Frontline Learning Research." The first paper offers a methodological guide using Ericsson & Smith's (1991) "expert performance approach." This is followed by three papers that analyze the use of eye tracking in visual expertise models, and a paper reviewing the use of methods…

Developing Pre-Technical Secondary Education Programs: Rationale, Content, and Methodology.

ERIC Educational Resources Information Center

Georgia State Univ., Atlanta. Dept. of Vocational and Career Development.

This guide outlines the rationale, content, and methodology of a three-part high technology program that was developed in Georgia to provide secondary school students with training in the areas of electronics and electromechanical and mechanical technologies. Discussed first are the Georgia Initiative, the impact of high technology and the role of…

Troubling the Boundaries: Overcoming Methodological Challenges in a Multi-Sectoral and Multi-Jurisdictional HIV/HCV Policy Scoping Review

ERIC Educational Resources Information Center

Hare, Kathleen A.; Dubé, Anik; Marshall, Zack; Gahagan, Jacqueline; Harris, Gregory E.; Tucker, Maryanne; Dykeman, Margaret; MacDonald, Jo-Ann

2016-01-01

Policy scoping reviews are an effective method for generating evidence-informed policies. However, when applying guiding methodological frameworks to complex policy evidence, numerous, unexpected challenges can emerge. This paper details five challenges experienced and addressed by a policy trainee-led, multi-disciplinary research team, while…

A Comprehensive Competence-Based Approach in Curriculum Development: Experiences from African and European Contexts

ERIC Educational Resources Information Center

Parent, F.; Baulana, R.; Kahombo, G.; Coppieters, Y.; Garant, M.; De Ketele, J.-M.

2011-01-01

Objective: To describe the methodological steps of developing an integrated reference guide for competences according to the profile of the healthcare professionals concerned. Design: Human resources in healthcare represent a complex issue, which needs conceptual and methodological frameworks and tools to help one understand reality and the limits…

PRECEPT: an evidence assessment framework for infectious disease epidemiology, prevention and control.

PubMed

Harder, Thomas; Takla, Anja; Eckmanns, Tim; Ellis, Simon; Forland, Frode; James, Roberta; Meerpohl, Joerg J; Morgan, Antony; Rehfuess, Eva; Schünemann, Holger; Zuiderent-Jerak, Teun; de Carvalho Gomes, Helena; Wichmann, Ole

2017-10-01

Decisions in public health should be based on the best available evidence, reviewed and appraised using a rigorous and transparent methodology. The Project on a Framework for Rating Evidence in Public Health (PRECEPT) defined a methodology for evaluating and grading evidence in infectious disease epidemiology, prevention and control that takes different domains and question types into consideration. The methodology rates evidence in four domains: disease burden, risk factors, diagnostics and intervention. The framework guiding it has four steps going from overarching questions to an evidence statement. In step 1, approaches for identifying relevant key areas and developing specific questions to guide systematic evidence searches are described. In step 2, methodological guidance for conducting systematic reviews is provided; 15 study quality appraisal tools are proposed and an algorithm is given for matching a given study design with a tool. In step 3, a standardised evidence-grading scheme using the Grading of Recommendations Assessment, Development and Evaluation Working Group (GRADE) methodology is provided, whereby findings are documented in evidence profiles. Step 4 consists of preparing a narrative evidence summary. Users of this framework should be able to evaluate and grade scientific evidence from the four domains in a transparent and reproducible way.

PRECEPT: an evidence assessment framework for infectious disease epidemiology, prevention and control

PubMed Central

Harder, Thomas; Takla, Anja; Eckmanns, Tim; Ellis, Simon; Forland, Frode; James, Roberta; Meerpohl, Joerg J; Morgan, Antony; Rehfuess, Eva; Schünemann, Holger; Zuiderent-Jerak, Teun; de Carvalho Gomes, Helena; Wichmann, Ole

2017-01-01

Decisions in public health should be based on the best available evidence, reviewed and appraised using a rigorous and transparent methodology. The Project on a Framework for Rating Evidence in Public Health (PRECEPT) defined a methodology for evaluating and grading evidence in infectious disease epidemiology, prevention and control that takes different domains and question types into consideration. The methodology rates evidence in four domains: disease burden, risk factors, diagnostics and intervention. The framework guiding it has four steps going from overarching questions to an evidence statement. In step 1, approaches for identifying relevant key areas and developing specific questions to guide systematic evidence searches are described. In step 2, methodological guidance for conducting systematic reviews is provided; 15 study quality appraisal tools are proposed and an algorithm is given for matching a given study design with a tool. In step 3, a standardised evidence-grading scheme using the Grading of Recommendations Assessment, Development and Evaluation Working Group (GRADE) methodology is provided, whereby findings are documented in evidence profiles. Step 4 consists of preparing a narrative evidence summary. Users of this framework should be able to evaluate and grade scientific evidence from the four domains in a transparent and reproducible way. PMID:29019317

Ballistic Resistance of Armored Passenger Vehicles: Test Protocols and Quality Methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jeffrey M. Lacy; Robert E. Polk

2005-07-01

This guide establishes a test methodology for determining the overall ballistic resistance of the passenger compartment of assembled nontactical armored passenger vehicles (APVs). Because ballistic testing of every piece of every component of an armored vehicle is impractical, if not impossible, this guide describes a testing scheme based on statistical sampling of exposed component surface areas. Results from the test of the sampled points are combined to form a test score that reflects the probability of ballistic penetration into the passenger compartment of the vehicle.

Oral immunotherapy for food allergy: A Spanish guideline. Immunotherapy egg and milk Spanish guide (items guide). Part I: Cow milk and egg oral immunotherapy: Introduction, methodology, rationale, current state, indications contraindications and oral immunotherapy build-up phase.

PubMed

Martorell, A; Alonso, E; Echeverría, L; Escudero, C; García-Rodríguez, R; Blasco, C; Bone, J; Borja-Segade, J; Bracamonte, T; Claver, A; Corzo, J L; De la Hoz, B; Del Olmo, R; Dominguez, O; Fuentes-Aparicio, V; Guallar, I; Larramona, H; Martín-Muñoz, F; Matheu, V; Michavila, A; Ojeda, I; Ojeda, P; Piquer, M; Poza, P; Reche, M; Rodríguez Del Río, P; Rodríguez, M; Ruano, F; Sánchez-García, S; Terrados, S; Valdesoiro, L; Vazquez-Ortiz, M

Cow's milk and egg are the most frequent causes of food allergy in the first years of life. Treatments such as oral immunotherapy (OIT) have been investigated as an alternative to avoidance diets. No clinical practice guides on the management of OIT with milk and egg are currently available. To develop a clinical guide on OIT based on the available scientific evidence and the opinions of experts. A review was made of studies published in the period between 1984 and June 2016, Doctoral Theses published in Spain, and summaries of communications at congresses (SEAIC, SEICAP, EAACI, AAAAI), with evaluation of the opinion consensus established by a group of experts pertaining to the scientific societies SEICAP and SEAIC. Recommendations have been established regarding the indications, requirements and practical aspects of the different phases of OIT, as well as special protocols for patients at high risk of suffering adverse reactions. A clinical practice guide is presented for the management of OIT with milk and egg, based on the opinion consensus of Spanish experts. Copyright © 2017 SEICAP. Published by Elsevier España, S.L.U. All rights reserved.

Intraoperative MR-guided DBS implantation for treating PD and ET

NASA Astrophysics Data System (ADS)

Liu, Haiying; Maxwell, Robert E.; Truwit, Charles L.

2001-05-01

Deep brain stimulator (DBS) implantation is a promising treatment alternative for suppressing the motor tremor symptoms in Parkinson disease (PD) patient. The main objective is to develop a minimally invasive approach using high spatial resolution and soft-tissue contrast MR imaging techniques to guide the surgical placement of DBS. In the MR-guided procedure, the high spatial resolution MR images were obtained intra-operatively and used to target stereotactically a specific deep brain location. The neurosurgery for craniotomy was performed in the front of the magnet outside of the 10 Gauss line. Aided with positional registration assembly for the stereotactic head frame, the target location (VIM or GPi or STN) in deep brain areas was identified and measured from the MR images in reference to the markers in the calibration assembly of the head frame before the burrhole prep. In 20 patients, MR- guided DBS implantations have been performed according to the new methodology. MR-guided DBS implantation at high magnetic field strength has been shown to be feasible and desirable. In addition to the improved outcome, this offers a new surgical approach in which intra-operative visualization is possible during intervention, and any complications such as bleeding can be assessed in situ immediately prior to dural closure.

HyRAM V1.0 User Guide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Groth, Katrina M.; Zumwalt, Hannah Ruth; Clark, Andrew Jordan

2016-03-01

Hydrogen Risk Assessment Models (HyRAM) is a prototype software toolkit that integrates data and methods relevant to assessing the safety of hydrogen fueling and storage infrastructure. The HyRAM toolkit integrates deterministic and probabilistic models for quantifying accident scenarios, predicting physical effects, and characterizing the impact of hydrogen hazards, including thermal effects from jet fires and thermal pressure effects from deflagration. HyRAM version 1.0 incorporates generic probabilities for equipment failures for nine types of components, and probabilistic models for the impact of heat flux on humans and structures, with computationally and experimentally validated models of various aspects of gaseous hydrogen releasemore » and flame physics. This document provides an example of how to use HyRAM to conduct analysis of a fueling facility. This document will guide users through the software and how to enter and edit certain inputs that are specific to the user-defined facility. Description of the methodology and models contained in HyRAM is provided in [1]. This User’s Guide is intended to capture the main features of HyRAM version 1.0 (any HyRAM version numbered as 1.0.X.XXX). This user guide was created with HyRAM 1.0.1.798. Due to ongoing software development activities, newer versions of HyRAM may have differences from this guide.« less

Guide to context sensitive solutions.

DOT National Transportation Integrated Search

2006-06-01

Context sensitive solutions are being implemented by the New Mexico Department of Transportation (NMDOT) in its transportation planning and project delivery processes. The NMDOT seeks to incorporate CSS methodologies and techniques into its planning,...

Automated Guided Vehicle For Phsically Handicapped People - A Cost Effective Approach

NASA Astrophysics Data System (ADS)

Kumar, G. Arun, Dr.; Sivasubramaniam, Mr. A.

2017-12-01

Automated Guided vehicle (AGV) is like a robot that can deliver the materials from the supply area to the technician automatically. This is faster and more efficient. The robot can be accessed wirelessly. A technician can directly control the robot to deliver the components rather than control it via a human operator (over phone, computer etc. who has to program the robot or ask a delivery person to make the delivery). The vehicle is automatically guided through its ways. To avoid collisions a proximity sensor is attached to the system. The sensor senses the signals of the obstacles and can stop the vehicle in the presence of obstacles. Thus vehicle can avoid accidents that can be very useful to the present industrial trend and material handling and equipment handling will be automated and easy time saving methodology.

The retrospective chart review: important methodological considerations.

PubMed

Vassar, Matt; Holzmann, Matthew

2013-01-01

In this paper, we review and discuss ten common methodological mistakes found in retrospective chart reviews. The retrospective chart review is a widely applicable research methodology that can be used by healthcare disciplines as a means to direct subsequent prospective investigations. In many cases in this review, we have also provided suggestions or accessible resources that researchers can apply as a "best practices" guide when planning, conducting, or reviewing this investigative method.

[Integral Care Guide for Early Detection and Diagnosis of Depressive Episodes and Recurrent Depressive Disorder in Adults. Integral Attention of Adults with a Diagnosis of Depressive Episodes and Recurrent Depressive Disorder: Part III: Treatment of Resistant Depression and Psychotic Depression, Occupational Therapy and Day Hospital Treatment].

PubMed

Gómez-Restrepo, Carlos; Peñaranda, Adriana Patricia Bohórquez; Valencia, Jenny García; Guarín, Maritza Rodríguez; Ángel, Juliana Rodríguez; Jaramillo, Luis Eduardo; Acosta, Carlos Alberto Palacio; Pedraza, Ricardo Sánchez; Díaz, Sergio Mario Castro; de la Hoz Bradford, Ana María

2012-12-01

This article presents recommendations based on the evidence gathered to answer a series of clinical questions concerning the depressive episode and the recurrent depressive disorder. Emphasis was given to general treatment issues of resistant depression and psychotic depression, occupational therapy and day hospital treatment so as to grant diagnosed adult patients the health care parameters based on the best and more updated evidence available and achieve minimum quality standards. A practical clinical guide was elaborated according to standards of the Methodological Guide of the Ministry of Social Protection. Recommendation from NICE90 and CANMAT guides were adopted and updated so as to answer the questions posed while de novo questions were developed. Recommendations 23-25 corresponding to the management of depression are presented. Copyright © 2012 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

Toward integrated image guided liver surgery

NASA Astrophysics Data System (ADS)

Jarnagin, W. R.; Simpson, Amber L.; Miga, M. I.

2017-03-01

While clinical neurosurgery has benefited from the advent of frameless image guidance for over three decades, the translation of image guided technologies to abdominal surgery, and more specifically liver resection, has been far more limited. Fundamentally, the workflow, complexity, and presentation have confounded development. With the first real efforts in translation beginning at the turn of the millennia, the work in developing novel augmented technologies to enhance screening, planning, and surgery has come to realization for the field. In this paper, we will review several examples from our own work that demonstrate the impact of image-guided procedure methods in eight clinical studies that speak to: (1) the accuracy in planning for liver resection, (2) enhanced surgical planning with portal vein embolization impact, (3) linking splenic volume changes to post-hepatectomy complications, (4) enhanced intraoperative localization in surgically occult lesions, (5) validation of deformation correction, and a (6) a novel blinded study focused at the value of deformation correction. All six of these studies were achieved in human systems and show the potential impact image guided methodologies could make on liver tissue resection procedures.

GREENSCOPE Technical User’s Guide

EPA Pesticide Factsheets

GREENSCOPE’s methodology has been developed and its software tool designed such that it can be applied to an entire process, to a piece of equipment or process unit, or at the investigatory bench scale.

Development of reliable pavement models.

DOT National Transportation Integrated Search

2011-05-01

The current report proposes a framework for estimating the reliability of a given pavement structure as analyzed by : the Mechanistic-Empirical Pavement Design Guide (MEPDG). The methodology proposes using a previously fit : response surface, in plac...

Algorithm for cellular reprogramming.

PubMed

Ronquist, Scott; Patterson, Geoff; Muir, Lindsey A; Lindsly, Stephen; Chen, Haiming; Brown, Markus; Wicha, Max S; Bloch, Anthony; Brockett, Roger; Rajapakse, Indika

2017-11-07

The day we understand the time evolution of subcellular events at a level of detail comparable to physical systems governed by Newton's laws of motion seems far away. Even so, quantitative approaches to cellular dynamics add to our understanding of cell biology. With data-guided frameworks we can develop better predictions about, and methods for, control over specific biological processes and system-wide cell behavior. Here we describe an approach for optimizing the use of transcription factors (TFs) in cellular reprogramming, based on a device commonly used in optimal control. We construct an approximate model for the natural evolution of a cell-cycle-synchronized population of human fibroblasts, based on data obtained by sampling the expression of 22,083 genes at several time points during the cell cycle. To arrive at a model of moderate complexity, we cluster gene expression based on division of the genome into topologically associating domains (TADs) and then model the dynamics of TAD expression levels. Based on this dynamical model and additional data, such as known TF binding sites and activity, we develop a methodology for identifying the top TF candidates for a specific cellular reprogramming task. Our data-guided methodology identifies a number of TFs previously validated for reprogramming and/or natural differentiation and predicts some potentially useful combinations of TFs. Our findings highlight the immense potential of dynamical models, mathematics, and data-guided methodologies for improving strategies for control over biological processes. Copyright © 2017 the Author(s). Published by PNAS.

The Effectiveness of High-Energy Extracorporeal Shockwave Therapy Versus Ultrasound-Guided Needling Versus Arthroscopic Surgery in the Management of Chronic Calcific Rotator Cuff Tendinopathy: A Systematic Review.

PubMed

Louwerens, Jan K G; Veltman, Ewout S; van Noort, Arthur; van den Bekerom, Michel P J

2016-01-01

The objectives of this comprehensive quantitative review of the treatment of calcific tendinopathy of the rotator cuff were to investigate if there is a sustainable positive effect on outcomes after treatment with high-energy extracorporeal shockwave therapy (ESWT) or ultrasound (US)-guided needling and to compare these results with those of treatment with arthroscopic surgery. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed to conduct this review. A systematic literature search was conducted in December 2014 to identify relevant clinical articles in peer-reviewed journals with at least 6 months' follow-up. Each article was scored using the Coleman Methodology Score. The primary endpoints were functional outcome and radiologic change in the size of the calcific deposit. Twenty-two studies were included (1,258 shoulders). The mean Coleman Methodology Score for the included studies was 77.1 ± 9.1. Overall, good to excellent clinical outcomes were achieved after treatment with either high-energy ESWT, US-guided needling, or arthroscopic surgery, with an improvement in the Constant-Murley score ranging between 26.3 and 41.5 points after 1 year. No severe side effects or long-term complications were encountered. Patients can achieve good to excellent clinical outcomes after high-energy ESWT, US-guided needling, and arthroscopy for calcific tendinopathy of the shoulder. Side effects and post-treatment complications should be taken into account when a decision is being made for each individual patient. Physicians should consider high-energy ESWT and US-guided needling as minimally invasive treatment options when primary conservative treatment fails. Arthroscopy can safely be used as a very effective but more invasive secondary option, although the extent of deposit removal and the additional benefit of subacromial decompression remain unclear. Level IV, systematic review of Level I, II, and IV studies. Copyright © 2016 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

The Case for Mixed Methodologies in Researching the Teacher's Use of Humour in Adult Education

ERIC Educational Resources Information Center

Struthers, John

2011-01-01

Inconsistencies within the literature result in teachers not having sufficient guidance to develop their humour use in support of learning without risking their professionalism. This article argues for more comprehensive evidence to guide teachers' use of humour, based on mixed methodological approaches. The case is also made for the Interpersonal…

A Methodological Framework for Instructional Design Model Development: Critical Dimensions and Synthesized Procedures

ERIC Educational Resources Information Center

Lee, Jihyun; Jang, Seonyoung

2014-01-01

Instructional design (ID) models have been developed to promote understandings of ID reality and guide ID performance. As the number and diversity of ID practices grows, implicit doubts regarding the reliability, validity, and usefulness of ID models suggest the need for methodological guidance that would help to generate ID models that are…

Case Study Methodology: Flexibility, Rigour, and Ethical Considerations for the Scholarship of Teaching and Learning

ERIC Educational Resources Information Center

Pearson, Marion L.; Albon, Simon P.; Hubball, Harry

2015-01-01

Individuals and teams engaging in the scholarship of teaching and learning (SoTL) in multidisciplinary higher education settings must make decisions regarding choice of research methodology and methods. These decisions are guided by the research context and the goals of the inquiry. With reference to our own recent experiences investigating…

Using Indigenous Educational Research to Transform Mainstream Education: A Guide for P-12 School Leaders

ERIC Educational Resources Information Center

Harrington, Billie Graham; CHiXapkaid (Pavel, D. Michael)

2013-01-01

The principal assertion of this article is that Indigenous research methodologies should be used to develop educational policies and practices for Native students. The history of American educational research is marred by a near complete dismissal of Indigenous knowledge, as Western research methodologies continue to define the landscape of P-12…

Using Enactivism as a Methodology to Characterise Algebraic Learning

ERIC Educational Resources Information Center

Lozano, Maria-Dolores

2015-01-01

My purpose in this paper is to illustrate the way in which an enactivist methodological approach guided me as I conducted a two-case longitudinal study where the learning of algebra was explored in different contexts throughout time. Three groups of students in two different schools in the city of Puebla, Mexico, were followed from the last year…

The Garbage Crisis: Environmental Issues for Adult ESL Learners.

ERIC Educational Resources Information Center

Heffernan, Helen

This module on the garbage crisis is for intermediate and advanced learners of English as a Second Language. It seeks to inform learners about this issue and to give them an opportunity to direct their concerns about the environment into positive action. The guide uses the problem-posing methodology of Paulo Freire. This methodology has three…

Investigating the spatial accuracy of CBCT-guided cranial radiosurgery: A phantom end-to-end test study.

PubMed

Calvo-Ortega, Juan-Francisco; Hermida-López, Marcelino; Moragues-Femenía, Sandra; Pozo-Massó, Miquel; Casals-Farran, Joan

2017-03-01

To evaluate the spatial accuracy of a frameless cone-beam computed tomography (CBCT)-guided cranial radiosurgery (SRS) using an end-to-end (E2E) phantom test methodology. Five clinical SRS plans were mapped to an acrylic phantom containing a radiochromic film. The resulting phantom-based plans (E2E plans) were delivered four times. The phantom was setup on the treatment table with intentional misalignments, and CBCT-imaging was used to align it prior to E2E plan delivery. Comparisons (global gamma analysis) of the planned and delivered dose to the film were performed using a commercial triple-channel film dosimetry software. The necessary distance-to-agreement to achieve a 95% (DTA95) gamma passing rate for a fixed 3% dose difference provided an estimate of the spatial accuracy of CBCT-guided SRS. Systematic (∑) and random (σ) error components, as well as 95% confidence levels were derived for the DTA95 metric. The overall systematic spatial accuracy averaged over all tests was 1.4mm (SD: 0.2mm), with a corresponding 95% confidence level of 1.8mm. The systematic (Σ) and random (σ) spatial components of the accuracy derived from the E2E tests were 0.2mm and 0.8mm, respectively. The E2E methodology used in this study allowed an estimation of the spatial accuracy of our CBCT-guided SRS procedure. Subsequently, a PTV margin of 2.0mm is currently used in our department. Copyright © 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

Airport Landside. Volume I. Planning Guide.

DOT National Transportation Integrated Search

1982-01-01

This volume describes a methodology for performing airport landside planning by applying the Airport Landside Simulation Model (ALSIM) developed by TSC. For this analysis, the airport landside is defined as extending from the airport boundary to the ...

Evaluation of automated decisionmaking methodologies and development of an integrated robotic system simulation. Appendix B: ROBSIM programmer's guide

NASA Technical Reports Server (NTRS)

Haley, D. C.; Almand, B. J.; Thomas, M. M.; Krauze, L. D.; Gremban, K. D.; Sanborn, J. C.; Kelly, J. H.; Depkovich, T. M.; Wolfe, W. J.; Nguyen, T.

1986-01-01

The purpose of the Robotic Simulation (ROBSIM) program is to provide a broad range of computer capabilities to assist in the design, verification, simulation, and study of robotic systems. ROBSIM is programmed in FORTRAM 77 and implemented on a VAX 11/750 computer using the VMS operating system. The programmer's guide describes the ROBSIM implementation and program logic flow, and the functions and structures of the different subroutines. With the manual and the in-code documentation, an experienced programmer can incorporate additional routines and modify existing ones to add desired capabilities.

Making meaning in qualitative research with conversational partnerships: a methodological discussion.

PubMed

Hunter Revell, Susan M

2013-01-01

Rubin and Rubin's responsive interviewing method is based on the conversational partnership formed between researcher and participant. This method allows the researcher to understand experiences through the participant's words and stories to create meaning. In this article, the reader is guided through a 3-part interview series with a person living with traumatic spinal cord injury. The example focuses on how interview guides were developed and tailored to the participant, and how field notations were created. Findings include the importance of establishing trust and rapport in conversational partnerships for meaning making to occur.

Quantitative diagnostics of multilayered composite structures with ultrasonic guided waves

NASA Astrophysics Data System (ADS)

Bunget, Gheorghe; Friedersdorf, Fritz; Na, Jeong K.

2015-03-01

The main objective of the current work is to develop a practical nondestructive inspection methodology for a highly sound absorbing composite structural system consisting of polymeric and metallic materials. Due to constraints in geometrical shapes and thicknesses of the composite system used in this work, ultrasonic guided wave approach has been chosen. Since the polymer coatings have high damping properties, less energy is dissipated into the adjacent media in the presence of interface delaminations. Experimental measurements performed on a targeted composite system, whether it has an aluminum, carbon-fiber-composite, or steel outer casing, show promising results.

An Alternative Methodological Approach for Cost-Effectiveness Analysis and Decision Making in Genomic Medicine.

PubMed

Fragoulakis, Vasilios; Mitropoulou, Christina; van Schaik, Ron H; Maniadakis, Nikolaos; Patrinos, George P

2016-05-01

Genomic Medicine aims to improve therapeutic interventions and diagnostics, the quality of life of patients, but also to rationalize healthcare costs. To reach this goal, careful assessment and identification of evidence gaps for public health genomics priorities are required so that a more efficient healthcare environment is created. Here, we propose a public health genomics-driven approach to adjust the classical healthcare decision making process with an alternative methodological approach of cost-effectiveness analysis, which is particularly helpful for genomic medicine interventions. By combining classical cost-effectiveness analysis with budget constraints, social preferences, and patient ethics, we demonstrate the application of this model, the Genome Economics Model (GEM), based on a previously reported genome-guided intervention from a developing country environment. The model and the attendant rationale provide a practical guide by which all major healthcare stakeholders could ensure the sustainability of funding for genome-guided interventions, their adoption and coverage by health insurance funds, and prioritization of Genomic Medicine research, development, and innovation, given the restriction of budgets, particularly in developing countries and low-income healthcare settings in developed countries. The implications of the GEM for the policy makers interested in Genomic Medicine and new health technology and innovation assessment are also discussed.

Implementing "Voix et Images de France, Part 1," in American Schools and Colleges. Section 1, Principles of Audio-Visual Language-Teaching.

ERIC Educational Resources Information Center

Renard, Colette; And Others

Principles of the "St. Cloud" audiovisual language instruction methodology based on "Le Francais fondamental" are presented in this guide for teachers. The material concentrates on course content, methodology, and application--including criteria for selection and gradation of course content, a description of the audiovisual and written language…

The Brazilian National Curriculum for Foreign Languages Revisited through a Multiculturalism and Peace Studies Approach

ERIC Educational Resources Information Center

Costa, Rejane Pinto

2011-01-01

This study emerged from a broader research completed during my Masters Course. (THEORY/METHODOLOGY) Theory and methodology were guided by the critical multiculturalism as seen in McLaren (1997, 2000). In my doctoral thesis, this concept was deepened by and linked to the peace studies of Galtung (1990, 2005, 2006), to empower multicultural peace…

Alternative occupied volume integrity (OVI) tests and analyses.

DOT National Transportation Integrated Search

2013-10-01

FRA, supported by the Volpe Center, conducted research on alternative methods of evaluating occupied volume integrity (OVI) in passenger railcars. Guided by this research, an alternative methodology for evaluating OVI that ensures an equivalent or gr...

A Philosophical Rationale and Practical Guide to Raising the "CQ" - Caring Quality - in Education ... A Moral Imperative.

ERIC Educational Resources Information Center

Kobak, Dorothy

1987-01-01

Argues that successful education must include teaching children to care. Outlines how a caring capacity can be developed and incorporated into educational methodology through action oriented projects. (BSR)

"The Need to Know": 1994 Senior Researcher Award Acceptance Address.

ERIC Educational Resources Information Center

Carlsen, James C.

1994-01-01

Discusses issues related to music education research. Presents three criteria to guide selection of research topics. Concludes that the challenge for music researchers is to avoid research that merely supports a "favored" methodology. (ACM)

Transportation research methods : a guide to searching for funding opportunities.

DOT National Transportation Integrated Search

2017-03-01

This project developed a training methodology focused on external funding. This hands-on training presented the basics of external funding identification, teambuilding and collaborative partners, and proposal element design. Real-time searches and tu...

Perimeter Barrier Selection Guide

DOT National Transportation Integrated Search

1989-05-01

This document provides a methodology to determine the magnitude of the threat from attack vehicles to the perimeter of a facility. The threat is determined by the penetration tolerance and the maximum speed attainable. After the threat is defined thi...

Waste treatability guidance program. User`s guide. Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Toth, C.

1995-12-21

DOE sites across the country generate and manage radioactive, hazardous, mixed, and sanitary wastes. It is necessary for each site to find the technologies and associated capacities required to manage its waste. One role of DOE HQ Office of Environmental Restoration and Waste Management is to facilitate the integration of the site- specific plans into coherent national plans. DOE has developed a standard methodology for defining and categorizing waste streams into treatability groups based on characteristic parameters that influence waste management technology needs. This Waste Treatability Guidance Program automates the Guidance Document for the categorization of waste information into treatabilitymore » groups; this application provides a consistent implementation of the methodology across the National TRU Program. This User`s Guide provides instructions on how to use the program, including installations instructions and program operation. This document satisfies the requirements of the Software Quality Assurance Plan.« less

microMS: A Python Platform for Image-Guided Mass Spectrometry Profiling

NASA Astrophysics Data System (ADS)

Comi, Troy J.; Neumann, Elizabeth K.; Do, Thanh D.; Sweedler, Jonathan V.

2017-09-01

Image-guided mass spectrometry (MS) profiling provides a facile framework for analyzing samples ranging from single cells to tissue sections. The fundamental workflow utilizes a whole-slide microscopy image to select targets of interest, determine their spatial locations, and subsequently perform MS analysis at those locations. Improving upon prior reported methodology, a software package was developed for working with microscopy images. microMS, for microscopy-guided mass spectrometry, allows the user to select and profile diverse samples using a variety of target patterns and mass analyzers. Written in Python, the program provides an intuitive graphical user interface to simplify image-guided MS for novice users. The class hierarchy of instrument interactions permits integration of new MS systems while retaining the feature-rich image analysis framework. microMS is a versatile platform for performing targeted profiling experiments using a series of mass spectrometers. The flexibility in mass analyzers greatly simplifies serial analyses of the same targets by different instruments. The current capabilities of microMS are presented, and its application for off-line analysis of single cells on three distinct instruments is demonstrated. The software has been made freely available for research purposes. [Figure not available: see fulltext.

microMS: A Python Platform for Image-Guided Mass Spectrometry Profiling.

PubMed

Comi, Troy J; Neumann, Elizabeth K; Do, Thanh D; Sweedler, Jonathan V

2017-09-01

Image-guided mass spectrometry (MS) profiling provides a facile framework for analyzing samples ranging from single cells to tissue sections. The fundamental workflow utilizes a whole-slide microscopy image to select targets of interest, determine their spatial locations, and subsequently perform MS analysis at those locations. Improving upon prior reported methodology, a software package was developed for working with microscopy images. microMS, for microscopy-guided mass spectrometry, allows the user to select and profile diverse samples using a variety of target patterns and mass analyzers. Written in Python, the program provides an intuitive graphical user interface to simplify image-guided MS for novice users. The class hierarchy of instrument interactions permits integration of new MS systems while retaining the feature-rich image analysis framework. microMS is a versatile platform for performing targeted profiling experiments using a series of mass spectrometers. The flexibility in mass analyzers greatly simplifies serial analyses of the same targets by different instruments. The current capabilities of microMS are presented, and its application for off-line analysis of single cells on three distinct instruments is demonstrated. The software has been made freely available for research purposes. Graphical Abstract ᅟ.

Mixing methodology, nursing theory and research design for a practice model of district nursing advocacy.

PubMed

Reed, Frances M; Fitzgerald, Les; Rae, Melanie

2016-01-01

To highlight philosophical and theoretical considerations for planning a mixed methods research design that can inform a practice model to guide rural district nursing end of life care. Conceptual models of nursing in the community are general and lack guidance for rural district nursing care. A combination of pragmatism and nurse agency theory can provide a framework for ethical considerations in mixed methods research in the private world of rural district end of life care. Reflection on experience gathered in a two-stage qualitative research phase, involving rural district nurses who use advocacy successfully, can inform a quantitative phase for testing and complementing the data. Ongoing data analysis and integration result in generalisable inferences to achieve the research objective. Mixed methods research that creatively combines philosophical and theoretical elements to guide design in the particular ethical situation of community end of life care can be used to explore an emerging field of interest and test the findings for evidence to guide quality nursing practice. Combining philosophy and nursing theory to guide mixed methods research design increases the opportunity for sound research outcomes that can inform a nursing model of care.

Pressurized air injection in an axial hydro-turbine model for the mitigation of tip leakage cavitation

NASA Astrophysics Data System (ADS)

Rivetti, A.; Angulo, M.; Lucino, C.; Liscia, S.

2015-12-01

Tip leakage vortex cavitation in axial hydro-turbines may cause erosion, noise and vibration. Damage due to cavitation can be found at the tip of the runner blades on the low pressure side and the discharge ring. In some cases, the erosion follows an oscillatory pattern that is related to the number of guide vanes. That might suggest that a relationship exists between the flow through the guide vanes and the tip vortex cavitating core that induces this kind of erosion. On the other hand, it is known that air injection has a beneficial effect on reducing the damage by cavitation. In this paper, a methodology to identify the interaction between guide vanes and tip vortex cavitation is presented and the effect of air injection in reducing this particular kind of erosion was studied over a range of operating conditions on a Kaplan scale model. It was found that air injection, at the expense of slightly reducing the efficiency of the turbine, mitigates the erosive potential of tip leakage cavitation, attenuates the interaction between the flow through the guide vanes and the tip vortex and decreases the level of vibration of the structural components.

Systematic Review Methodology for the Fatigue in Emergency Medical Services Project

DOT National Transportation Integrated Search

2018-01-11

Background: Guidance for managing fatigue in the Emergency Medical Services (EMS) setting is limited. The Fatigue in EMS Project sought to complete multiple systematic reviews guided by seven explicit research questions, assemble the best available e...

A Comprehensive Guide to C3 System Development

DTIC Science & Technology

1990-03-01

This thesis provides guidelines to develop a C3 system, including both organizational and physical systems. It contains the concept, architecture ... design and engineering approaches, the integrated C3 framework, test and evaluation methodologies, system acquisition procedures, system development

Integrated Noise Model (INM) Version 6.0 User's Guide.

DOT National Transportation Integrated Search

1999-09-01

The FAA Office of Environment and Energy supports the assessment of aircraft noise impacts by developing and maintaining noise-evaluation models and methodologies. In particular, the FAA's Integrated Noise Model (INM) is widely used by the civilian a...

Monitoring iCCM: a feasibility study of the indicator guide for monitoring and evaluating integrated community case management.

PubMed

Roberton, Timothy; Kasungami, Dyness; Guenther, Tanya; Hazel, Elizabeth

2016-07-01

Most countries in sub-Saharan Africa have now adopted integrated community case management (iCCM) of common childhood illnesses as a strategy to improve child health. In March 2014, the iCCM Task Force published an Indicator Guide for Monitoring and Evaluating iCCM: a 'menu' of recommended indicators with globally agreed definitions and methodology, to guide countries in developing robust iCCM monitoring systems. The Indicator Guide was conceived as an evolving document that would incorporate collective experience and learning as iCCM programmes themselves evolve. This article presents findings from two studies that examined the feasibility of collecting the Indicator Guide's 18 routine monitoring indicators with the iCCM monitoring systems that countries currently have in place. We reviewed iCCM monitoring tools, protocols and reports from a purposive sample of 10 countries in sub-Saharan Africa. We developed a scorecard system to assess which of the Indicator Guide's 18 routine monitoring indicators could be calculated with the given monitoring tools, and at which level of the health system the relevant information would be available. We found that the data needed to calculate many of the Indicator Guide's routine monitoring indicators are already being collected through existing monitoring systems, although much of these data are only available at health facility level and not aggregated to district or national levels. Our results highlight challenge of using supervision checklists as a data source, and the need for countries to maintain accurate deployment data for CHWs and CHW supervisors. We suggest that some of the recommended indicators need revising. Routine monitoring will be more feasible, effective and efficient if iCCM programmes focus on a smaller set of high-value indicators that are easy to measure, reliably interpreted and useful both for global and national stakeholders and for frontline health workers themselves. © The Author 2016. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.

Generating Artificial Snort Alerts and Implementing SELK: The Snort-Elasticsearch-Logstash-Kibana Stack

DTIC Science & Technology

2017-09-01

analyzing Snort alerts. The first section covers the Snort alert-generation program, the methodology involved in developing it, and how it accelerates...guide on system setup. The methodologies described can be translated to the setup and use of the ELK stack for storing and visualizing any data...Figures iv List of Tables iv 1. Introduction 1 2. Methodology 2 2.1. Snort Alert Generation 2 2.2 The SELK Stack 8 3. Discussion and Conclusion 11

Guia Para El Mejoramiento de la Produccion de Materiales Para la Educacion Formal y No Formal. Guias Metodologicas No. 6. (Guide for the Improvement of Production of Educational Materials for Formal and Non-formal Education. Methodology Guide No. 6). Revised Proceedings from the Regional Workshop on Improvement of the Production of Educational Materials on Teaching Population Education: Primary and Secondary Level (Santiago, Chile, May 27-June 5, 1987).

ERIC Educational Resources Information Center

Calvo, Gilbert

Various educators from Latin and Central America and the Caribbean met to design and produce materials for teaching family life, human sexuality, community life, and environmental studies. They concluded that the materials should meet community standards; help prepare for future change; develop working models for designing effective teaching…

Technical Support Document: Development of the Advanced Energy Design Guide for K-12 Schools--30% Energy Savings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pless, S.; Torcellini, P.; Long, N.

2007-09-01

This Technical Support Document describes the process and methodology for the development of the Advanced Energy Design Guide for K-12 School Buildings (K-12 AEDG), a design guidance document intended to provide recommendations for achieving 30% energy savings in K-12 Schools over levels contained in ANSI/ASHRAE/IESNA Standard 90.1-1999, Energy Standard for Buildings Except Low-Rise Residential Buildings. The 30% energy savings target is the first step toward achieving net-zero energy schools; schools that, on an annual basis, draw from outside sources less or equal energy than they generate on site from renewable energy sources.

[International bibliographic databases--Current Contents on disk and in FTP format (Internet): presentation and guide].

PubMed

Bloch-Mouillet, E

1999-01-01

This paper aims to provide technical and practical advice about finding references using Current Contents on disk (Macintosh or PC) or via the Internet (FTP). Seven editions are published each week. They are all organized in the same way and have the same search engine. The Life Sciences edition, extensively used in medical research, is presented here in detail, as an example. This methodological note explains, in French, how to use this reference database. It is designed to be a practical guide for browsing and searching the database, and particularly for creating search profiles adapted to the needs of researchers.

A traffic data plan for mechanistic-empirical pavement designs (2002 pavement design guide).

DOT National Transportation Integrated Search

2003-01-01

The Virginia Department of Transportation (VDOT) is preparing to implement the mechanistic-empirical pavement design methodology being developed under the National Cooperative Research Program's Project 1-37A, commonly referred to as the 2002 Pavemen...

Investigation of Dynamic Modulus and Flow Number Properties of Asphalt Mixtures In Washington State

DOT National Transportation Integrated Search

2011-11-11

Pavement design is now moving toward more mechanistic based design methodologies for the purpose of producing long : lasting and higher performance pavements in a cost-effective manner. The recent Mechanistic-Empirical pavement : design guide (MEPDG)...

The image-guided surgery toolkit IGSTK: an open source C++ software toolkit.

PubMed

Enquobahrie, Andinet; Cheng, Patrick; Gary, Kevin; Ibanez, Luis; Gobbi, David; Lindseth, Frank; Yaniv, Ziv; Aylward, Stephen; Jomier, Julien; Cleary, Kevin

2007-11-01

This paper presents an overview of the image-guided surgery toolkit (IGSTK). IGSTK is an open source C++ software library that provides the basic components needed to develop image-guided surgery applications. It is intended for fast prototyping and development of image-guided surgery applications. The toolkit was developed through a collaboration between academic and industry partners. Because IGSTK was designed for safety-critical applications, the development team has adopted lightweight software processes that emphasizes safety and robustness while, at the same time, supporting geographically separated developers. A software process that is philosophically similar to agile software methods was adopted emphasizing iterative, incremental, and test-driven development principles. The guiding principle in the architecture design of IGSTK is patient safety. The IGSTK team implemented a component-based architecture and used state machine software design methodologies to improve the reliability and safety of the components. Every IGSTK component has a well-defined set of features that are governed by state machines. The state machine ensures that the component is always in a valid state and that all state transitions are valid and meaningful. Realizing that the continued success and viability of an open source toolkit depends on a strong user community, the IGSTK team is following several key strategies to build an active user community. These include maintaining a users and developers' mailing list, providing documentation (application programming interface reference document and book), presenting demonstration applications, and delivering tutorial sessions at relevant scientific conferences.

Product environmental footprint in policy and market decisions: Applicability and impact assessment.

PubMed

Lehmann, Annekatrin; Bach, Vanessa; Finkbeiner, Matthias

2015-07-01

In April 2013, the European Commission published the Product and Organisation Environmental Footprint (PEF/OEF) methodology--a life cycle-based multicriteria measure of the environmental performance of products, services, and organizations. With its approach of "comparability over flexibility," the PEF/OEF methodology aims at harmonizing existing methods, while decreasing the flexibility provided by the International Organization for Standardization (ISO) standards regarding methodological choices. Currently, a 3-y pilot phase is running, aiming at testing the methodology and developing product category and organization sector rules (PEFCR/OEFSR). Although a harmonized method is in theory a good idea, the PEF/OEF methodology presents challenges, including a risk of confusion and limitations in applicability to practice. The paper discusses the main differences between the PEF and ISO methodologies and highlights challenges regarding PEF applicability, with a focus on impact assessment. Some methodological aspects of the PEF and PEFCR Guides are found to contradict the ISO 14044 (2006) and ISO 14025 (2006). Others, such as prohibition of inventory cutoffs, are impractical. The evaluation of the impact assessment methods proposed in the PEF/OEF Guide showed that the predefined methods for water consumption, land use, and abiotic resources are not adequate because of modeling artefacts, missing inventory data, or incomplete characterization factors. However, the methods for global warming and ozone depletion perform very well. The results of this study are relevant for the PEF (and OEF) pilot phase, which aims at testing the PEF (OEF) methodology (and potentially adapting it) as well as addressing challenges and coping with them. © 2015 SETAC.

Advanced Energy Retrofit Guide: Practical Ways to Improve Energy Performance, K-12 Schools (Book)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The U.S. Department of Energy developed the Advanced Energy Retrofit Guides (AERGs) to provide specific methodologies, information, and guidance to help energy managers and other stakeholders plan and execute energy efficiency improvements. Detailed technical discussion is fairly limited. Instead, we emphasize actionable information, practical methodologies, diverse case studies, and unbiased evaluations of the most promising retrofit energy efficiency measures for each building type. A series of AERGs is under development, addressing key segments of the commercial building stock. K-12 schools were selected as one of the highest priority building sectors, because schools affect the lives of most Americans. They alsomore » represent approximately 8% of the energy use and 10% of the floor area in commercial buildings nationwide. U.S. K-12 school districts spend more than $8 billion each year on energy - more than they spend on computers and textbooks combined. Most occupy older buildings that often have poor operational performance - more than 30% of schools were built before 1960. The average age of a school is about 42 years - which is nearly the expected serviceable lifespan of the building. K-12 schools offer unique opportunities for deep, cost-effective energy efficiency improvements, and this guide provides convenient and practical guidance for exploiting these opportunities in the context of public, private, and parochial schools.« less

Direct Administration of Nerve-Specific Contrast to Improve Nerve Sparing Radical Prostatectomy

PubMed Central

Barth, Connor W.; Gibbs, Summer L.

2017-01-01

Nerve damage remains a major morbidity following nerve sparing radical prostatectomy, significantly affecting quality of life post-surgery. Nerve-specific fluorescence guided surgery offers a potential solution by enhancing nerve visualization intraoperatively. However, the prostate is highly innervated and only the cavernous nerve structures require preservation to maintain continence and potency. Systemic administration of a nerve-specific fluorophore would lower nerve signal to background ratio (SBR) in vital nerve structures, making them difficult to distinguish from all nervous tissue in the pelvic region. A direct administration methodology to enable selective nerve highlighting for enhanced nerve SBR in a specific nerve structure has been developed herein. The direct administration methodology demonstrated equivalent nerve-specific contrast to systemic administration at optimal exposure times. However, the direct administration methodology provided a brighter fluorescent nerve signal, facilitating nerve-specific fluorescence imaging at video rate, which was not possible following systemic administration. Additionally, the direct administration methodology required a significantly lower fluorophore dose than systemic administration, that when scaled to a human dose falls within the microdosing range. Furthermore, a dual fluorophore tissue staining method was developed that alleviates fluorescence background signal from adipose tissue accumulation using a spectrally distinct adipose tissue specific fluorophore. These results validate the use of the direct administration methodology for specific nerve visualization with fluorescence image-guided surgery, which would improve vital nerve structure identification and visualization during nerve sparing radical prostatectomy. PMID:28255352

Direct Administration of Nerve-Specific Contrast to Improve Nerve Sparing Radical Prostatectomy.

PubMed

Barth, Connor W; Gibbs, Summer L

2017-01-01

Nerve damage remains a major morbidity following nerve sparing radical prostatectomy, significantly affecting quality of life post-surgery. Nerve-specific fluorescence guided surgery offers a potential solution by enhancing nerve visualization intraoperatively. However, the prostate is highly innervated and only the cavernous nerve structures require preservation to maintain continence and potency. Systemic administration of a nerve-specific fluorophore would lower nerve signal to background ratio (SBR) in vital nerve structures, making them difficult to distinguish from all nervous tissue in the pelvic region. A direct administration methodology to enable selective nerve highlighting for enhanced nerve SBR in a specific nerve structure has been developed herein. The direct administration methodology demonstrated equivalent nerve-specific contrast to systemic administration at optimal exposure times. However, the direct administration methodology provided a brighter fluorescent nerve signal, facilitating nerve-specific fluorescence imaging at video rate, which was not possible following systemic administration. Additionally, the direct administration methodology required a significantly lower fluorophore dose than systemic administration, that when scaled to a human dose falls within the microdosing range. Furthermore, a dual fluorophore tissue staining method was developed that alleviates fluorescence background signal from adipose tissue accumulation using a spectrally distinct adipose tissue specific fluorophore. These results validate the use of the direct administration methodology for specific nerve visualization with fluorescence image-guided surgery, which would improve vital nerve structure identification and visualization during nerve sparing radical prostatectomy.

A Novel Framework for Identifying the Interactions between Biophysical and Social Components of an Agricultural System: A Guide for Improving Wheat Production in Haryana, NW India

ERIC Educational Resources Information Center

Coventry, D. R.; Poswal, R. S.; Yadav, Ashok; Zhou, Yi; Riar, Amritbir; Kumar, Anuj; Sharma, R. K.; Chhokar, R. S.; Gupta, R. K.; Mehta, A. K.; Chand, Ramesh; Denton, M. D.; Cummins, J. A.

2018-01-01

Purpose: The purpose of this study is to develop a conceptual framework with related analysis methodologies that identifies the influence of social environment on an established cropping system. Design/Methodology/Approach: A stratified survey including 103 villages and 823 farmers was conducted in all districts of Haryana (India). Firstly,…

Interstate 73 economic impact analysis : a guide to the methodology and results, part 2.

DOT National Transportation Integrated Search

1994-01-01

The Transportation Planning Division of the Virginia Department of Transportation (VDOT) is currently considering seven corridors along which VDOT may build the future Interstate 73. The purpose of this technical assistance project is to estimate the...

A Selected Bibliography of Educational Sources.

ERIC Educational Resources Information Center

Campbell, Janet; And Others

Focusing on materials available at the California State University at Long Beach Library, this annotated bibliography lists resources in seven subject categories pertaining to education: (1) guides to the professional educational literature; (2) books about education research methodology; (3) encyclopedias and dictionaries; (4) tests and…

Sociology through Photography

ERIC Educational Resources Information Center

Hyde, Katherine

2015-01-01

This chapter describes how photography can inspire and cultivate sociological mindfulness. One set of assignments uses self-portraiture to highlight the complexity of visual representations of social identity. Another uses photography to guide sociological inquiry. Both sets of assignments draw on the Literacy Through Photography methodology,…

A Hitchhiker's Guide to Functional Magnetic Resonance Imaging

PubMed Central

Soares, José M.; Magalhães, Ricardo; Moreira, Pedro S.; Sousa, Alexandre; Ganz, Edward; Sampaio, Adriana; Alves, Victor; Marques, Paulo; Sousa, Nuno

2016-01-01

Functional Magnetic Resonance Imaging (fMRI) studies have become increasingly popular both with clinicians and researchers as they are capable of providing unique insights into brain functions. However, multiple technical considerations (ranging from specifics of paradigm design to imaging artifacts, complex protocol definition, and multitude of processing and methods of analysis, as well as intrinsic methodological limitations) must be considered and addressed in order to optimize fMRI analysis and to arrive at the most accurate and grounded interpretation of the data. In practice, the researcher/clinician must choose, from many available options, the most suitable software tool for each stage of the fMRI analysis pipeline. Herein we provide a straightforward guide designed to address, for each of the major stages, the techniques, and tools involved in the process. We have developed this guide both to help those new to the technique to overcome the most critical difficulties in its use, as well as to serve as a resource for the neuroimaging community. PMID:27891073

Analyzing the impacts of global trade and investment on non-communicable diseases and risk factors: a critical review of methodological approaches used in quantitative analyses.

PubMed

Cowling, Krycia; Thow, Anne Marie; Pollack Porter, Keshia

2018-05-24

A key mechanism through which globalization has impacted health is the liberalization of trade and investment, yet relatively few studies to date have used quantitative methods to investigate the impacts of global trade and investment policies on non-communicable diseases and risk factors. Recent reviews of this literature have found heterogeneity in results and a range of quality across studies, which may be in part attributable to a lack of conceptual clarity and methodological inconsistencies. This study is a critical review of methodological approaches used in the quantitative literature on global trade and investment and diet, tobacco, alcohol, and related health outcomes, with the objective of developing recommendations and providing resources to guide future robust, policy relevant research. A review of reviews, expert review, and reference tracing were employed to identify relevant studies, which were evaluated using a novel quality assessment tool designed for this research. Eight review articles and 34 quantitative studies were identified for inclusion. Important ways to improve this literature were identified and discussed: clearly defining exposures of interest and not conflating trade and investment; exploring mechanisms of broader relationships; increasing the use of individual-level data; ensuring consensus and consistency in key confounding variables; utilizing more sector-specific versus economy-wide trade and investment indicators; testing and adequately adjusting for autocorrelation and endogeneity when using longitudinal data; and presenting results from alternative statistical models and sensitivity analyses. To guide the development of future analyses, recommendations for international data sources for selected trade and investment indicators, as well as key gaps in the literature, are presented. More methodologically rigorous and consistent approaches in future quantitative studies on the impacts of global trade and investment policies on non-communicable diseases and risk factors can help to resolve inconsistencies of existing research and generate useful information to guide policy decisions.

Can nurse teachers manage student incivility by guided democracy? A grounded theory study

PubMed Central

Rad, Mostafa; Ildarabadi, Eshagh

2017-01-01

Introduction Managing incivility in academic settings is among the basic concerns and challenges of most educational systems, including nursing education. Incivility management cannot be considered devoid of disruptive behaviors. However, incivility management is a complexphenomenon upon which few studies are conducted. Objectives The present study aims at discovering teachers and students’ experiences regarding incivility and developing an approach to manage nursing students’ incivility. Design The present study was conducted based on the qualitative research design of the grounded theory methodology. Settings This study was conducted at schools of nursing in academic settings in Iran. Participants Study participants in the present study include nurse teachers (N=20) and nursing students (N=9). Method In-depth semi-structured interviews were conducted using theoretical and purposive sampling. Constant comparative analysis was used for data analysis. Results The results include four main categories; (1) deterioration of learning; (2) dominant individual and organisational culture; (3) guided democracy; and (4) movement toward professionalism. Guided democracy is recognised as the main basic psychosocial process for incivility management. Conclusions Incivility management is pursued to help learners develop professional performance. As indicated by the results of the present study, guided democracy is an effective strategy for incivility management in nursing education. PMID:28716787

Maldives. Package on population education for special interest groups developed.

PubMed

1995-01-01

The Population Education Program of the Non-Formal Education Center has developed a package of Population Education for Special Interest Groups comprising a learning package and fieldworker's guide. The learning package is especially developed for teaching population education for out-of-school populations. Special interest groups in Maldives include newly married couples, adolescents, and working youth. Produced under the guidance of UNESCO, Bangkok, the package contains 36 different materials such as posters, charts, leaflets, booklets, stories, and illustrated booklets which may be taught in 36 to 45 periods. The materials deal with eight themes, namely, family size and family welfare, population and resources, delayed marriage and parenthood, responsible parenthood, population-related values and beliefs, women in development, AIDS/STD, and respect for old people. Accompanying the learning package is the fieldworker's guide used to teach the package. It contains individual guides for each of the 36 learning materials. The guide gives the titles of the materials, format, objectives of the materials, messages, target groups, and an overview of the content of each learning materials. The methodologies used for teaching the learning materials include role playing, group discussion, questioning, brainstorming, survey, creative writing, problem-solving and evaluation. The package will be used by fieldworkers to conduct island-based population education courses. full text

[Integral Care Guide for Early Detection and Diagnosis of Depressive Episodes and Recurrent Depressive Disorder in Adults. Integral Attention of Adults with a Diagnosis of Depressive Episodes and Recurrent Depressive Disorder: Part I: Risk Factors, Screening, Suicide Risk Diagnosis and Assessment in Patients with a Depression Diagnosis].

PubMed

Gómez-Restrepo, Carlos; Peñaranda, Adriana Patricia Bohórquez; Valencia, Jenny García; Guarín, Maritza Rodríguez; Narváez, Eliana Bravo; Jaramillo, Luis Eduardo; Acosta, Carlos Alberto Palacio; Pedraza, Ricardo Sánchez; Díaz, Sergio Mario Castro

2012-12-01

Depression is an important cause of morbidity and disability in the world; however, it is under-diagnosed at all care levels. The purpose here is to present recommendations based on the evidence gathered to answer a series of clinical questions concerning risk factors, screening, suicide risk diagnosis and evaluation in patients undergoing a depressive episode and recurrent depressive disorder. Emphasis has been made upon the approach used at the primary care level so as to grant adult diagnosed patients the health care guidelines based on the best and more updated evidence available thus achieving minimum quality standards. A practical clinical guide was elaborated according to standards of the Methodological Guide of the Ministry of Social Protection. Recommendation from guides NICE90 and CANMAT were adopted and updated so as to answer the questions posed while de novo questions were developed. Recommendations 1-22 corresponding to screening, suicide risk and depression diagnosis were presented. The corresponding degree of recommendation is included. Copyright © 2012 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

Measures of outdoor play and independent mobility in children and youth: A methodological review.

PubMed

Bates, Bree; Stone, Michelle R

2015-09-01

Declines in children's outdoor play have been documented globally, which are partly due to heightened restrictions around children's independent mobility. Literature on outdoor play and children's independent mobility is increasing, yet no paper has summarized the various methodological approaches used. A methodological review could highlight most commonly used measures and comprehensive research designs that could result in more standardized methodological approaches. Methodological review. A standardized protocol guided a methodological review of published research on measures of outdoor play and children's independent mobility in children and youth (0-18 years). Online searches of 8 electronic databases were conducted and studies included if they contained a subjective/objective measure of outdoor play or children's independent mobility. References of included articles were scanned to identify additional articles. Twenty-four studies were included on outdoor play, and twenty-three on children's independent mobility. Study designs were diverse. Common objective measures included accelerometry, global positioning systems and direct observation; questionnaires, surveys and interviews were common subjective measures. Focus groups, activity logs, monitoring sheets, travel/activity diaries, behavioral maps and guided tours were also utilized. Questionnaires were used most frequently, yet few studies used the same questionnaire. Five studies employed comprehensive, mixed-methods designs. Outdoor play and children's independent mobility have been measured using a wide variety of techniques, with only a few studies using similar methodologies. A standardized methodological approach does not exist. Future researchers should consider including both objective measures (accelerometry and global positioning systems) and subjective measures (questionnaires, activity logs, interviews), as more comprehensive designs will enhance understanding of each multidimensional construct. Creating a standardized methodological approach would improve study comparisons. Copyright © 2014 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Survey of Key Concepts in Enactivist Theory and Methodology

ERIC Educational Resources Information Center

Reid, David A.; Mgombelo, Joyce

2015-01-01

This article discusses key concepts within enactivist writing, focussing especially on concepts involved in the enactivist description of cognition as embodied action: perceptually guided action, embodiment, and structural coupling through recurrent sensorimotor patterns. Other concepts on which these concepts depend are also discussed, including…

Incorporating hydrologic data and ecohydrologic relationships in ecological site descriptions

USDA-ARS?s Scientific Manuscript database

The purpose of this paper is to recommend a framework and methodology for inclusion of key ecohydrologic feedbacks and relationships in Ecological Site Descriptions (ESDs) and thereby enhance the utility of ESDs for assessing rangelands and guiding resilience-based management strategies. Resilience...

A Phenomenological Exploration of Adoption

ERIC Educational Resources Information Center

Baltimore, Diana L.; Crase, Sedahlia Jasper

2009-01-01

This qualitative analysis explored children's and adults' experiences with adoption. We used phenomenological methodology and individually interviewed 25 participants and included adoptive mothers and fathers, and their children, each adopted before 18 months of age. Two research questions guided the data analysis: (a) What are children's and…

The road to successful ITS software acquisition. Volume 2, Software acquisition process reference guide

DOT National Transportation Integrated Search

2000-12-01

The current performance-related specifications (PRS) methodology has been under development by the Federal Highway Administration (FHWA) for several years and has now reached a level at which it can be implemented by State highway agencies. PRS for h...

Highway Safety Information System guidebook for the Maine state data files. Volume 1 : SAS file formats

DOT National Transportation Integrated Search

2012-05-05

As part of the Federal Highway Administration (FHWA) Traffic Analysis Toolbox (Volume XIII), this guide was designed to help corridor stakeholders implement the ICM AMS methodology successfully and effectively. It provides a step-by-step approach to ...

Would the Real Corporate University Please Stand Up?

ERIC Educational Resources Information Center

Walton, John

2005-01-01

Purpose: Aims to investigate the similarities and differences between traditional and corporate universities and determine whether their respective futures will continue to plough separate furrows or converge. Design/methodology/approach: Examines mission statements, core values, guiding principles, aims and objectives from a sample of traditional…

Recommended Best Practices for the Characterization of Storage Properties of Hydrogen Storage Materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2010-03-01

This is a reference guide to common methodologies and protocols for measuring critical performance properties of advanced hydrogen storage materials. It helps users to communicate clearly the relevant performance properties of new materials as they are discovered and tested.

Contracting Officer Technical Representative Briefing

NASA Technical Reports Server (NTRS)

Gettleman, Alan

2001-01-01

This viewgraph presentation gives an overview of the Agency Occupational Health Program, including details on organizational and personnel changes, medical program standardization, programmatic status, policies, standards, and guides and resources, industrial hygiene and radiological health, assessment schedule and methodology, upcoming events, and the future of the program.

Therapeutic Jurisprudence in Health Research: Enlisting Legal Theory as a Methodological Guide in an Interdisciplinary Case Study of Mental Health and Criminal Law.

PubMed

Ferrazzi, Priscilla; Krupa, Terry

2015-09-01

Studies that seek to understand and improve health care systems benefit from qualitative methods that employ theory to add depth, complexity, and context to analysis. Theories used in health research typically emerge from social science, but these can be inadequate for studying complex health systems. Mental health rehabilitation programs for criminal courts are complicated by their integration within the criminal justice system and by their dual health-and-justice objectives. In a qualitative multiple case study exploring the potential for these mental health court programs in Arctic communities, we assess whether a legal theory, known as therapeutic jurisprudence, functions as a useful methodological theory. Therapeutic jurisprudence, recruited across discipline boundaries, succeeds in guiding our qualitative inquiry at the complex intersection of mental health care and criminal law by providing a framework foundation for directing the study's research questions and the related propositions that focus our analysis. © The Author(s) 2014.

Future Air Traffic Growth and Schedule Model User's Guide

NASA Technical Reports Server (NTRS)

Kimmel, William M. (Technical Monitor); Smith, Jeremy C.; Dollyhigh, Samuel M.

2004-01-01

The Future Air Traffic Growth and Schedule Model was developed as an implementation of the Fratar algorithm to project future traffic flow between airports in a system and of then scheduling the additional flights to reflect current passenger time-of-travel preferences. The methodology produces an unconstrained future schedule from a current (or baseline) schedule and the airport operations growth rates. As an example of the use of the model, future schedules are projected for 2010 and 2022 for all flights arriving at, departing from, or flying between all continental United States airports that had commercial scheduled service for May 17, 2002. Inter-continental US traffic and airports are included and the traffic is also grown with the Fratar methodology to account for their arrivals and departures to the continental US airports. Input data sets derived from the Official Airline Guide (OAG) data and FAA Terminal Area Forecast (TAF) are included in the examples of the computer code execution.

Australasian nutrition research for prevention and management of child obesity: innovation and progress in the last decade.

PubMed

Golley, R K; McNaughton, S A; Collins, C E; Magarey, A; Garnett, S P; Campbell, K J; Mallan, K; Burrows, T

2014-12-01

The Food and Nutrition stream of Australasian Child and Adolescent Obesity Research Network (ACAORN) aims to improve the quality of dietary methodologies and the reporting of dietary intake within Australasian child obesity research (http://www.acaorn.org.au/streams/nutrition/). With 2012 marking ACAORN's 10th anniversary, this commentary profiles a selection of child obesity nutrition research published over the last decade by Food and Nutrition Stream members. In addition, stream activities have included the development of an online selection guide to assist researchers in their selection of appropriate dietary intake methodologies (http://www.acaorn.org.au/streams/nutrition/dietary-intake/index.php). The quantity and quality of research to guide effective child obesity prevention and treatment has increased substantially over the last decade. ACAORN provides a successful case study of how research networks can provide a collegial atmosphere to foster and coordinate research efforts in an otherwise competitive environment. © 2014 The Authors. Pediatric Obesity © 2014 International Association for the Study of Obesity.

Evaluating and redesigning teaching learning sequences at the introductory physics level

NASA Astrophysics Data System (ADS)

Guisasola, Jenaro; Zuza, Kristina; Ametller, Jaume; Gutierrez-Berraondo, José

2017-12-01

In this paper we put forward a proposal for the design and evaluation of teaching and learning sequences in upper secondary school and university. We will connect our proposal with relevant contributions on the design of teaching sequences, ground it on the design-based research methodology, and discuss how teaching and learning sequences designed according to our proposal relate to learning progressions. An iterative methodology for evaluating and redesigning the teaching and learning sequence (TLS) is presented. The proposed assessment strategy focuses on three aspects: (a) evaluation of the activities of the TLS, (b) evaluation of learning achieved by students in relation to the intended objectives, and (c) a document for gathering the difficulties found when implementing the TLS to serve as a guide to teachers. Discussion of this guide with external teachers provides feedback used for the TLS redesign. The context of our implementation and evaluation is an innovative calculus-based physics course for first-year engineering and science degree students at the University of the Basque Country.

Control of microtubule trajectory within an electric field by altering surface charge density

PubMed Central

Isozaki, Naoto; Ando, Suguru; Nakahara, Tasuku; Shintaku, Hirofumi; Kotera, Hidetoshi; Meyhöfer, Edgar; Yokokawa, Ryuji

2015-01-01

One of challenges for using microtubules (MTs) driven by kinesin motors in microfluidic environments is to control their direction of movement. Although applying physical biases to rectify MTs is prevalent, it has not been established as a design methodology in conjunction with microfluidic devices. In the future, the methodology is expected to achieve functional motor-driven nanosystems. Here, we propose a method to guide kinesin-propelled MTs in multiple directions under an electric field by designing a charged surface of MT minus ends labeled with dsDNA via a streptavidin-biotin interaction. MTs labeled with 20-bp or 50-bp dsDNA molecules showed significantly different trajectories according to the DNA length, which were in good agreement with values predicted from electrophoretic mobilities measured for their minus ends. Since the effective charge of labeled DNA molecules was equal to that of freely dispersed DNA molecules in a buffer solution, MT trajectory could be estimated by selecting labeling molecules with known charges. Moreover, the estimated trajectory enables to define geometrical sizes of a microfluidic device. This rational molecular design and prediction methodology allows MTs to be guided in multiple directions, demonstrating the feasibility of using molecular sorters driven by motor proteins. PMID:25567007

Control of microtubule trajectory within an electric field by altering surface charge density.

PubMed

Isozaki, Naoto; Ando, Suguru; Nakahara, Tasuku; Shintaku, Hirofumi; Kotera, Hidetoshi; Meyhöfer, Edgar; Yokokawa, Ryuji

2015-01-08

One of challenges for using microtubules (MTs) driven by kinesin motors in microfluidic environments is to control their direction of movement. Although applying physical biases to rectify MTs is prevalent, it has not been established as a design methodology in conjunction with microfluidic devices. In the future, the methodology is expected to achieve functional motor-driven nanosystems. Here, we propose a method to guide kinesin-propelled MTs in multiple directions under an electric field by designing a charged surface of MT minus ends labeled with dsDNA via a streptavidin-biotin interaction. MTs labeled with 20-bp or 50-bp dsDNA molecules showed significantly different trajectories according to the DNA length, which were in good agreement with values predicted from electrophoretic mobilities measured for their minus ends. Since the effective charge of labeled DNA molecules was equal to that of freely dispersed DNA molecules in a buffer solution, MT trajectory could be estimated by selecting labeling molecules with known charges. Moreover, the estimated trajectory enables to define geometrical sizes of a microfluidic device. This rational molecular design and prediction methodology allows MTs to be guided in multiple directions, demonstrating the feasibility of using molecular sorters driven by motor proteins.

Application of tolerance limits to the characterization of image registration performance.

PubMed

Fedorov, Andriy; Wells, William M; Kikinis, Ron; Tempany, Clare M; Vangel, Mark G

2014-07-01

Deformable image registration is used increasingly in image-guided interventions and other applications. However, validation and characterization of registration performance remain areas that require further study. We propose an analysis methodology for deriving tolerance limits on the initial conditions for deformable registration that reliably lead to a successful registration. This approach results in a concise summary of the probability of registration failure, while accounting for the variability in the test data. The (β, γ) tolerance limit can be interpreted as a value of the input parameter that leads to successful registration outcome in at least 100β% of cases with the 100γ% confidence. The utility of the methodology is illustrated by summarizing the performance of a deformable registration algorithm evaluated in three different experimental setups of increasing complexity. Our examples are based on clinical data collected during MRI-guided prostate biopsy registered using publicly available deformable registration tool. The results indicate that the proposed methodology can be used to generate concise graphical summaries of the experiments, as well as a probabilistic estimate of the registration outcome for a future sample. Its use may facilitate improved objective assessment, comparison and retrospective stress-testing of deformable.

Development of a Tailored Methodology and Forensic Toolkit for Industrial Control Systems Incident Response

DTIC Science & Technology

2014-06-01

for industrial control systems ,” in Proceedings of the VDE Kongress, 2004. [15] K. Stouffer et al., “Special publication 800-82: Guide to industrial...TAILORED METHODOLOGY AND FORENSIC TOOLKIT FOR INDUSTRIAL CONTROL SYSTEMS INCIDENT RESPONSE by Nicholas B. Carr June 2014 Thesis Co...CONTROL SYSTEMS INCIDENT RESPONSE 5. FUNDING NUMBERS 6. AUTHOR(S) Nicholas B. Carr 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval

Forensic Schedule Analysis of Construction Delay in Military Projects in the Middle East

DTIC Science & Technology

This research performs forensic schedule analysis of delay factors that impacted recent large-scale military construction projects in the Middle East...The methodologies for analysis are adapted from the Professional Practice Guide to Forensic Schedule Analysis, particularly Method 3.7 Modeled

Transformative Mixed Methods Research

ERIC Educational Resources Information Center

Mertens, Donna M.

2010-01-01

Paradigms serve as metaphysical frameworks that guide researchers in the identification and clarification of their beliefs with regard to ethics, reality, knowledge, and methodology. The transformative paradigm is explained and illustrated as a framework for researchers who place a priority on social justice and the furtherance of human rights.…

76 FR 79194 - Agency Information Collection Activities; Proposed Collection; Comment Request; Prescription Drug...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-21

...] Agency Information Collection Activities; Proposed Collection; Comment Request; Prescription Drug Product... the distribution of patient labeling, called Medications Guides, for certain products that pose a... validity of the methodology and assumption used; (3) ways to enhance the quality, utility, and clarity of...

Improved prediction models for PCC pavement performance-related specifications, volume II : PaveSpec 3.0 user's guide.

DOT National Transportation Integrated Search

2001-12-01

The current performance-related specifications (PRS) methodology has been under development by the Federal : Highway~Administration (FI-IWA) for several years and has now reached a level at which it can be implemented by : State highway agencies. PRS...

The Slow Learning Program in the Elementary and Secondary Schools.

ERIC Educational Resources Information Center

Cincinnati Public Schools, OH.

The curriculum guide defines its organization and use, curricular approach, and the teaching methodology for special classes of slow learners (educable mentally handicapped) in the Cincinnati Public Schools. The instructional program is build around 12 persisting life problems; health, safety, communication, citizenship, family life, social…

Nickel hydrogen cell design: A designer's aspect

NASA Technical Reports Server (NTRS)

Rehm, Raymond

1992-01-01

Information is given to give insight into the methodology of nickel hydrogen cell design and the decipherment of the battery cell reference guide that was distributed to many of Gates Energy Products' customers. Cell design, stacking design, charge capacity, and dynamic response are discussed in general terms.

Learning Communities: An Untapped Sustainable Competitive Advantage for Higher Education

ERIC Educational Resources Information Center

Dawson, Shane; Burnett, Bruce; O' Donohue, Mark

2006-01-01

Purpose: This paper demonstrates the need for the higher education sector to develop and implement scaleable, quantitative measures that evaluate community and establish organisational benchmarks in order to guide the development of future practices designed to enhance the student learning experience. Design/methodology/approach: Literature…

Maintaining the Median in Early Childhood Educational Methodology

ERIC Educational Resources Information Center

Hewes, Dorothy W.

2005-01-01

History shows that educational systems and educational theorists have consciously or unconsciously structured the education of young children toward one end or the other of the continuum between "internals" and "externals". Systems in which teacher-guided learning was based on efforts to satisfy individual needs, systems that…

Summary of the Workshop on Methodologies for Environmental Public Health Tracking of Air Pollution Effects

EPA Science Inventory

The U.S. Centers for Disease Control and Prevention (CDC) established the Environmental Public Health Tracking (EPHT) program to support state and local projects to compile, link, analyze, and disseminate environmental and health data thereby engaging stakeholders and guiding act...

Parental Acceptance-Rejection Theory and the Phylogenetic Model.

ERIC Educational Resources Information Center

Rohner, Ronald P.

Guided by specific theoretical and methodological points of view--the phylogenetic perspective and the universalistic approach respectively--this paper reports on a worldwide study of the antecedents and effects of parental acceptance and rejection. Parental acceptance-rejection theory postulates that rejected children throughout our species share…

APPLICATION OF POLLUTION PREVENTION TECHNIQUES TO REDUCE INDOOR AIR EMISSONS FROM AEROSOL CONSUMER PRODUCTS

EPA Science Inventory

The report gives results of a research project to develop tools and methodologies to measure aerosol chemical and particle dispersion through space. These tools can be used to devise pollution prevention strategies that could reduce occupant chemical exposures and guide manufactu...

Functional Analysis and Treatment of Nail Biting

ERIC Educational Resources Information Center

Dufrene, Brad A.; Watson, T. Steuart; Kazmerski, Jennifer S.

2008-01-01

This study applied functional analysis methodology to nail biting exhibited by a 24-year-old female graduate student. Results from the brief functional analysis indicated variability in nail biting across assessment conditions. Functional analysis data were then used to guide treatment development and implementation. Treatment included a…

Accuracy Study of a Robotic System for MRI-guided Prostate Needle Placement

PubMed Central

Seifabadi, Reza; Cho, Nathan BJ.; Song, Sang-Eun; Tokuda, Junichi; Hata, Nobuhiko; Tempany, Clare M.; Fichtinger, Gabor; Iordachita, Iulian

2013-01-01

Background Accurate needle placement is the first concern in percutaneous MRI-guided prostate interventions. In this phantom study, different sources contributing to the overall needle placement error of a MRI-guided robot for prostate biopsy have been identified, quantified, and minimized to the possible extent. Methods and Materials The overall needle placement error of the system was evaluated in a prostate phantom. This error was broken into two parts: the error associated with the robotic system (called before-insertion error) and the error associated with needle-tissue interaction (called due-to-insertion error). The before-insertion error was measured directly in a soft phantom and different sources contributing into this part were identified and quantified. A calibration methodology was developed to minimize the 4-DOF manipulator’s error. The due-to-insertion error was indirectly approximated by comparing the overall error and the before-insertion error. The effect of sterilization on the manipulator’s accuracy and repeatability was also studied. Results The average overall system error in phantom study was 2.5 mm (STD=1.1mm). The average robotic system error in super soft phantom was 1.3 mm (STD=0.7 mm). Assuming orthogonal error components, the needle-tissue interaction error was approximated to be 2.13 mm thus having larger contribution to the overall error. The average susceptibility artifact shift was 0.2 mm. The manipulator’s targeting accuracy was 0.71 mm (STD=0.21mm) after robot calibration. The robot’s repeatability was 0.13 mm. Sterilization had no noticeable influence on the robot’s accuracy and repeatability. Conclusions The experimental methodology presented in this paper may help researchers to identify, quantify, and minimize different sources contributing into the overall needle placement error of an MRI-guided robotic system for prostate needle placement. In the robotic system analyzed here, the overall error of the studied system remained within the acceptable range. PMID:22678990

Organizational culture change in U.S. hospitals: a mixed methods longitudinal intervention study.

PubMed

Curry, Leslie A; Linnander, Erika L; Brewster, Amanda L; Ting, Henry; Krumholz, Harlan M; Bradley, Elizabeth H

2015-03-07

Improving outcomes for patients with acute myocardial infarction (AMI) is a priority for hospital leadership, clinicians, and policymakers. Evidence suggests links between hospital organizational culture and hospital performance; however, few studies have attempted to shift organizational culture in order to improve performance, fewer have focused on patient outcomes, and none have addressed mortality for patients with AMI. We sought to address this gap through a novel longitudinal intervention study, Leadership Saves Lives (LSL). This manuscript describes the methodology of LSL, a 2-year intervention study using a concurrent mixed methods design, guided by open systems theory and the Assess, Innovate, Develop, Engage, Devolve (AIDED) model of diffusion, implemented in 10 U.S. hospitals and their peer hospital networks. The intervention has three primary components: 1) annual convenings of the ten intervention hospitals; 2) semiannual workshops with guiding coalitions at each hospital; and 3) continuous remote support across all intervention hospitals through a web-based platform. Primary outcomes include 1) shifts in key dimensions of hospital organizational culture associated with lower mortality rates for patients with AMI; 2) use of targeted evidence-based practices associated with lower mortality rates for patients with AMI; and 3) in-hospital AMI mortality. Quantitative data include annual surveys of guiding coalition members in the intervention hospitals and peer network hospitals. Qualitative data include in-person, in-depth interviews with all guiding coalition members and selective observations of key interactions in care for patients with AMI, collected at three time points. Data integration will identify patterns and major themes in change processes across all intervention hospitals over time. LSL is novel in its use of a longitudinal mixed methods approach in a diverse sample of hospitals, its focus on objective outcome measures of mortality, and its examination of changes not only in the intervention hospitals but also in their peer hospital networks over time. This paper adds to the methodological literature for the study of complex interventions to promote hospital organizational culture change.

Accuracy study of a robotic system for MRI-guided prostate needle placement.

PubMed

Seifabadi, Reza; Cho, Nathan B J; Song, Sang-Eun; Tokuda, Junichi; Hata, Nobuhiko; Tempany, Clare M; Fichtinger, Gabor; Iordachita, Iulian

2013-09-01

Accurate needle placement is the first concern in percutaneous MRI-guided prostate interventions. In this phantom study, different sources contributing to the overall needle placement error of a MRI-guided robot for prostate biopsy have been identified, quantified and minimized to the possible extent. The overall needle placement error of the system was evaluated in a prostate phantom. This error was broken into two parts: the error associated with the robotic system (called 'before-insertion error') and the error associated with needle-tissue interaction (called 'due-to-insertion error'). Before-insertion error was measured directly in a soft phantom and different sources contributing into this part were identified and quantified. A calibration methodology was developed to minimize the 4-DOF manipulator's error. The due-to-insertion error was indirectly approximated by comparing the overall error and the before-insertion error. The effect of sterilization on the manipulator's accuracy and repeatability was also studied. The average overall system error in the phantom study was 2.5 mm (STD = 1.1 mm). The average robotic system error in the Super Soft plastic phantom was 1.3 mm (STD = 0.7 mm). Assuming orthogonal error components, the needle-tissue interaction error was found to be approximately 2.13 mm, thus making a larger contribution to the overall error. The average susceptibility artifact shift was 0.2 mm. The manipulator's targeting accuracy was 0.71 mm (STD = 0.21 mm) after robot calibration. The robot's repeatability was 0.13 mm. Sterilization had no noticeable influence on the robot's accuracy and repeatability. The experimental methodology presented in this paper may help researchers to identify, quantify and minimize different sources contributing into the overall needle placement error of an MRI-guided robotic system for prostate needle placement. In the robotic system analysed here, the overall error of the studied system remained within the acceptable range. Copyright © 2012 John Wiley & Sons, Ltd.

The methodological quality of systematic reviews of animal studies in dentistry.

PubMed

Faggion, C M; Listl, S; Giannakopoulos, N N

2012-05-01

Systematic reviews and meta-analyses of animal studies are important for improving estimates of the effects of treatment and for guiding future clinical studies on humans. The purpose of this systematic review was to assess the methodological quality of systematic reviews and meta-analyses of animal studies in dentistry through using a validated checklist. A literature search was conducted independently and in duplicate in the PubMed and LILACS databases. References in selected systematic reviews were assessed to identify other studies not captured by the electronic searches. The methodological quality of studies was assessed independently and in duplicate by using the AMSTAR checklist; the quality was scored as low, moderate, or high. The reviewers were calibrated before the assessment and agreement between them was assessed using Cohen's Kappa statistic. Of 444 studies retrieved, 54 systematic reviews were selected after full-text assessment. Agreement between the reviewers was regarded as excellent. Only two studies were scored as high quality; 17 and 35 studies were scored as medium and low quality, respectively. There is room for improvement of the methodological quality of systematic reviews of animal studies in dentistry. Checklists, such as AMSTAR, can guide researchers in planning and executing systematic reviews and meta-analyses. For determining the need for additional investigations in animals and in order to provide good data for potential application in human, such reviews should be based on animal experiments performed according to sound methodological principles. Copyright © 2011 Elsevier Ltd. All rights reserved.

Assessing E-Book Model Sustainability

ERIC Educational Resources Information Center

Polding, Robert; Baptista Nunes, Jose Miguel; Kingston, Bernard

2008-01-01

The project described in this article explores the transition from a paper-based book, which deals with higher education (HE) ranking tables, namely "The Times Good University Guide" (GUG), to a fully customizable e-book. This article sets the background of the project, identifies design research as the general methodological approach,…

Qualitative data collection with children.

PubMed

Spratling, Regena; Coke, Sallie; Minick, Ptlene

2012-02-01

Qualitative researchers have clear methods to guide them in data collection with adult participants, but little is known about effective interview techniques with children. The findings from this methodological study on qualitative interviews with children indicate that children are able to articulate their experiences in interviews. Copyright © 2012 Elsevier Inc. All rights reserved.

Incorporating hydrologic data and ecohydrologic relationships into ecological site descriptions

Treesearch

C. Jason Williams; Frederick B. Pierson; Kenneth E. Spaeth; Joel R. Brown; Osama Z. Al-Hamdan; Mark A. Weltz; Mark A. Nearing; Jeffrey E. Herrick; Jan Boll; Pete Robichaud; David C. Goodrich; Phillip Heilman; D. Phillip Guertin; Mariano Hernandez; Haiyan Wei; Stuart P. Hardegree; Eva K. Strand; Jonathan D. Bates; Loretta J. Metz; Mary H. Nichols

2016-01-01

The purpose of this paper is to recommend a framework and methodology for incorporating hydrologic data and ecohydrologic relationships in Ecological Site Descriptions (ESDs) and thereby enhance the utility of ESDs for assessing rangelands and guiding resilience-based management strategies. Resilience-based strategies assess and manage ecological state...

A Critical Review of International Students' Adjustment Research from a Deleuzian Perspective

ERIC Educational Resources Information Center

Vasilopoulos, Gene

2016-01-01

The author in this paper critically reviews recent literature on international student language and adjustment to Western Anglophone universities. Two streams of research are discussed: the problem-solving approach guided largely by positivist epistemologies and quantitative methodologies contrasted to the post-structuralist language and identity…

Averting Uncertainty: A Practical Guide to Physical Activity Research in Australian Schools

ERIC Educational Resources Information Center

Rachele, Jerome N.; Cuddihy, Thomas F.; Washington, Tracy L.; McPhail, Steven M.

2013-01-01

Preventative health has become central to contemporary health care, identifying youth physical activity as a key factor in determining health and functioning. Schools offer a unique research setting due to distinctive methodological circumstances. However, school-based researchers face several obstacles in their endeavour to complete successful…

Designing a Pedagogical Model for Web Engineering Education: An Evolutionary Perspective

ERIC Educational Resources Information Center

Hadjerrouit, Said

2005-01-01

In contrast to software engineering, which relies on relatively well established development approaches, there is a lack of a proven methodology that guides Web engineers in building reliable and effective Web-based systems. Currently, Web engineering lacks process models, architectures, suitable techniques and methods, quality assurance, and a…

Spirituality and Health: Implications for Policy and Practice

ERIC Educational Resources Information Center

Vazin, Dara

2013-01-01

Purpose. The purpose of this study was to establish among health educators a consensus in the definition of spirituality and health that would ultimately guide effective development of a curriculum or program in spirituality and health for undergraduate programs in college health science departments. Methodology. This mixed-methods research study…

Effectiveness of Guided Peer Review of Student Essays in a Large Undergraduate Biology Course

ERIC Educational Resources Information Center

Kelly, Lauren

2015-01-01

Instructors and researchers often consider peer review an integral part of the writing process, providing myriad benefits for both writers and reviewers. Few empirical studies, however, directly address the relationship between specific methodological changes and peer review effectiveness, especially outside the composition classroom. To…

A Multiperspective Analysis on Developing and Maintaining Trust in Senior Student Affairs Leadership

ERIC Educational Resources Information Center

Ruthkosky, Philip J.

2013-01-01

This study examines senior student affairs leadership through the diverse lenses of subordinates, administrative peers, presidents, and senior student affairs officers (SSAOs). Guided by an interpretive paradigm, a qualitative methodology was employed consisting of a six-case comparative analysis and grounded theory approach. The findings provide…

Psychological Universals: What Are They and How Can We Know?

ERIC Educational Resources Information Center

Norenzayan, Ara; Heine, Steven J.

2005-01-01

Psychological universals, or core mental attributes shared by humans everywhere, are a foundational postulate of psychology, yet explicit analysis of how to identify such universals is lacking. This article offers a conceptual and methodological framework to guide the investigation of genuine universals through empirical analysis of psychological…

Comparing Pedagogies for Plastic Waste Management at University Level

ERIC Educational Resources Information Center

Yeung, Siu-Kit; So, Wing-Mui Winnie; Cheng, Nga-Yee Irene; Cheung, Tsz-Yan; Chow, Cheuk-Fai

2017-01-01

Purpose: This paper aims to compare the learning outcomes of gaming simulation and guided inquiry in sustainability education on plastic waste management. The current study targets the identification of success factors in these teaching approaches. Design/methodology/approach: This study used a quasi-experimental design with undergraduate…

Learning Disabilities at Twenty-Five: The Early Adulthood of a Maturing Concept.

ERIC Educational Resources Information Center

Levine, Melvin D.

1989-01-01

The keynote speech identifies six categories of problem areas for children with learning disabilities: (1) synchronization, (2) consistency, (3) methodology, (4) cohesion, (5) saliency determination, and (6) tempo. A model of neurodevelopmental functions and performance elements to guide researchers and practitioners is offered. (DB)

Teaching Consumer Education. Delta Pi Epsilon Rapid Reader No. 2.

ERIC Educational Resources Information Center

Graf, David

This teaching guide provides secondary business teachers with ideas for teaching consumer education and assistance in strengthening the course content and methodology. Content is presented in four parts. Part 1 provides an overview of consumer education and covers the teacher, course objectives, content areas, and teaching-learning strategies…

Navigating the Complexity of Qualitative Research in Postmodern Contexts: Assemblage, Critical Reflexivity, and Communion as Guides

ERIC Educational Resources Information Center

Bettez, Silvia Cristina

2015-01-01

For graduate students and other emerging qualitative researchers, the ever-evolving and sometimes conflicting perspectives, methodologies, and practices within various post-positivist frameworks (e.g. feminist, critical, Indigenous, participatory) can be overwhelming. Qualitative researchers working within postmodern contexts of multiplicity and…

A Practical Guide for Estimating Dietary Fat and Fiber Using Limited Food Frequency Data.

ERIC Educational Resources Information Center

Neale, Anne Victoria; And Others

1992-01-01

A methodology is presented for estimating daily intake of dietary fat and fiber based on limited food frequency data. The procedure, which relies on National Food Consumption Survey data and daily consumption rates, can provide baseline estimates of dietary patterns for health promotion policymakers. (SLD)

Inter-Cultural Communication: A Foundation of Communicative Action

ERIC Educational Resources Information Center

Vuckovic, Aleksandra

2008-01-01

Purpose: The purpose of this paper is to present a model of inter-cultural communication that enumerates and structures latent factors affecting such communication and elaborates on the process of self-reflection as a guiding mechanism of successful communication. Design/methodology/approach: The five factors and various moderators that are…

Shared Governance in Times of Change: A Practical Guide for Universities and Colleges

ERIC Educational Resources Information Center

Bahls, Steven S.

2014-01-01

Today's challenging higher education environment demands a new way of making decisions. Changing business models and methodologies for delivering academic programs present new opportunities (as well as risks) and call for innovative responses. This publication aims to "reboot" dialogues among boards, presidents, and faculties. It creates…

Guide to the expression of uncertainty in measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mathew, Kattathu Joseph

The enabling objectives of this presentation are to: Provide a working knowledge of the ISO GUM method to estimation of uncertainties in safeguards measurements; Introduce GUM terminology; Provide brief historical background of the GUM methodology; Introduce GUM Workbench software; Isotope ratio measurements by MS will be discussed in the next session.

Finding a Voice through Research

ERIC Educational Resources Information Center

Lobo, Jose; Vizcaino, Alida

2006-01-01

One question guided this experimental study: What impact does the change from teacher training to educational research have on university teachers' methodology and attitudes to teaching? To find answers to this question, the researchers selected five teachers of English as a Foreign Language (EFL) at the language centre of a private university on…

Mexican American Mothers' Perceptions of Childhood Obesity: A Theory-Guided Systematic Literature Review

ERIC Educational Resources Information Center

Sosa, Erica T.

2012-01-01

Childhood obesity continues to increase, disproportionately affecting Mexican American children. The aims of this review are to (a) assess the literature regarding Mexican American mothers' knowledge and perceptions of childhood obesity, prevention, and their role in prevention; (b) critically evaluate the methodological quality of the research…

Basic Western Lviv Region Conversational Ukrainian

ERIC Educational Resources Information Center

Petryshyn, Ivan

2015-01-01

Purpose: To present the first complete Guide for studying the Western-Ukrainian Dialect and its scientific description of Phonology. Methodology: descriptive, contrastive and analytical methods of defining the peculiarities of the Dialect. Results: the regularities and the laws have been defined as to the specifics of the Western-Ukrainian Dialect…

Our Teachers and What We Have Learnt from Them

ERIC Educational Resources Information Center

Sander, Paul; Williamson, Stella

2010-01-01

In this contribution to the Widening Participation Special Issue of Psychology Teaching Review we consider our experiences in education as people who can't spell using an auto-ethnographic methodology (Sparkes, 2007), specifically, evocative auto-ethnography (Anderson, 2006) and guided by a social constructionist approach to identity (Burr, 1995).…

Re-Conceptualizing Adult Education's Monolithic Behaviourist Interpretation: Toward a New Understanding of Radical Behaviourism

ERIC Educational Resources Information Center

Roessger, Kevin M.

2012-01-01

The philosophy of radical behaviourism remains misunderstood within the field of adult education. Contributing to this trend is the field's homogeneous behaviourist interpretation, which attributes methodological behaviourism's principles to radical behaviourism. The guiding principles and assumptions of radical behaviourism are examined to…

Authentic Geometry Adventures

ERIC Educational Resources Information Center

Minetola, Janice; Serr, Konnie; Nelson, Laureen

2012-01-01

Teachers have the opportunity to capitalize on a vast array of real-world, two- and three-dimensional objects as they guide students in developing a conceptual understanding of geometric shapes. An important component of the NCTM Standards is to use teaching methodologies that engage children in making real-world connections to the mathematics…

Comprehension Literacy Improvement Program Implementation and Balanced Literacy Impact on Elementary Students

ERIC Educational Resources Information Center

Gough, Timothy Jerome

2017-01-01

The purpose of this study was to determine how teachers in an urban school district implemented Comprehensive Literacy Improvement Program (CLIP) and balanced literacy framework in second through fifth grade classrooms by exploring the evidence of implementation of guided reading strategies. Instructional delivery, training methodology, phonemic…

Quantitative Methodology: A Guide for Emerging Physical Education and Adapted Physical Education Researchers

ERIC Educational Resources Information Center

Haegele, Justin A.; Hodge, Samuel R.

2015-01-01

Emerging professionals, particularly senior-level undergraduate and graduate students in kinesiology who have an interest in physical education for individuals with and without disabilities, should understand the basic assumptions of the quantitative research paradigm. Knowledge of basic assumptions is critical for conducting, analyzing, and…

POLizied e-Learning Using Contract Management

ERIC Educational Resources Information Center

Espinosa, Espinosa David; Noguez, Julieta; Benes, Bedrich; Bueno, Abel

2005-01-01

We present an innovative way to manage online learning by administering experiential learning activities during a semester-long, web-based course that is designed with the Project Oriented Learning methodology. A consulting-style guiding thread for in-class and remote workshops is implemented using a professionally relevant project contract that…

Teaching Methodologies and Course Contents in International Finance.

ERIC Educational Resources Information Center

Garg, Ramesh C.

A guide to designing a course in international finance and multinational corporations is presented. It offers a rationale for such a course, discusses its primary goals, suggests two possible course orientations (professional or theoretical) and desirable or necessary prerequisites, and recommends specific course content areas and subareas. Types…

Revisiting Knowledge Sharing from the Organizational Change Perspective

ERIC Educational Resources Information Center

Park, Sunyoung; Kim, Eun-Jee

2015-01-01

Purpose: The purpose of this study is to identify how knowledge sharing literature has discussed task, structure, technology and people as elements of organizational change and to examine the interactions between the four elements of knowledge sharing. Design/methodology/approach: The research questions guiding the study are: How do organizational…

Translation Accommodations Framework for Testing English Language Learners in Mathematics

ERIC Educational Resources Information Center

Solano-Flores, Guillermo

2012-01-01

The present framework is developed under contract with the Smarter Balanced Assessment Consortium (SBAC) as a conceptual and methodological tool for guiding the reasonings and actions of contractors in charge of developing and providing test translation accommodations for English language learners. The framework addresses important challenges in…

A Call for Conducting Multivariate Mixed Analyses

ERIC Educational Resources Information Center

Onwuegbuzie, Anthony J.

2016-01-01

Several authors have written methodological works that provide an introductory- and/or intermediate-level guide to conducting mixed analyses. Although these works have been useful for beginning and emergent mixed researchers, with very few exceptions, works are lacking that describe and illustrate advanced-level mixed analysis approaches. Thus,…

Professional Norms Guiding School Principals' Pedagogical Leadership

ERIC Educational Resources Information Center

Leo, Ulf

2015-01-01

Purpose: The purpose of this paper is to identify and analyze the professional norms surrounding school development, with a special emphasis on school principals' pedagogical leadership. Design/methodology/approach: A norm perspective is used to identify possible links between legal norms, professional norms, and actions. The findings are based on…

Teachers as Partners in the Prevention of Childhood Obesity

ERIC Educational Resources Information Center

Bruss, Mozhdeh B.; Dannison, Linda; Morris, Joseph R.; Quitugua, Jackie; Palacios, Rosa T.; McGowan, Judy; Michael, Timothy

2010-01-01

This paper presents a community-school-higher education partnership approach to the prevention of childhood obesity. Public elementary school personnel, primarily teachers, participated in the design and delivery of a curriculum targeting primary caregivers of 8-9-year-old children. Theoretical framework and methodological approaches guided the…

An Improvement in Instructional Quality: Can Evaluation of Teaching Effectiveness Make a Difference?

ERIC Educational Resources Information Center

Ngware, Moses Waithanji; Ndirangu, Mwangi

2005-01-01

Purpose: To report study findings on teaching effectiveness and feedback mechanisms in Kenyan universities, which can guide management in developing a comprehensive quality control policy. Design/methodology/approach: The study adopted an exploratory descriptive design. Three public and two private universities were randomly selected to…

Guide for Implementing State Adopted Texts, 1969-1970.

ERIC Educational Resources Information Center

Sanchis, Robert A.; And Others

The materials and procedures used by the Fountain Valley School District, California, to implement their reading program are described. Included are a description of the reading principles on which the program is based and information on methodology and organizational procedures. Also described are lists of state-adopted texts, summaries of basic…

The Accuracy of Adult Narrative Reports of Developmental Trajectories

ERIC Educational Resources Information Center

Cohen, Patricia; Kasen, Stephanie; Bifulco, Antonia; Andrews, Howard; Gordon, Kathy

2005-01-01

This methodological investigation examines the accuracy of narrative-based scaled ratings covering several post high school years. Guided narratives by young adults described developmentally relevant behaviour and context for each month between ages 17 and the mid-20s. "Prospective" narratives covered shorter time periods in three interviews…

Conceptualizations of Professional Competencies in School Health Promotion

ERIC Educational Resources Information Center

Carlsson, Monica

2016-01-01

Purpose: The purpose of the paper is to contribute to the conceptualization and discussion of professional competencies needed for supporting the development of the whole-school approach in school health promotion (SHP). Design/methodology/approach: The paper is based on a conceptual synthesis of literature, guided by a theoretical perspective on…

Introduction: Qualitative Approaches to Research on Plurilingual Education

ERIC Educational Resources Information Center

Dooly, Melinda; Moore, Emilee

2017-01-01

This handbook has been conceived as a guide for young researchers embarking on the exciting journey of investigating different aspects of plurilingual education. The text can also serve to review ideas previously encountered, and perhaps as a means of interrogating research methodologies in plurilingual contexts for those who already have ample…

[Methodological quality of an article on the treatment of gastric cancer adopted as protocol by some Chilean hospitals].

PubMed

Manterola, Carlos; Torres, Rodrigo; Burgos, Luis; Vial, Manuel; Pineda, Viviana

2006-07-01

Surgery is a curative treatment for gastric cancer (GC). As relapse is frequent, adjuvant therapies such as postoperative chemo radiotherapy have been tried. In Chile, some hospitals adopted Macdonald's study as a protocol for the treatment of GC. To determine methodological quality and internal and external validity of the Macdonald study. Three instruments were applied that assess methodological quality. A critical appraisal was done and the internal and external validity of the methodological quality was analyzed with two scales: MINCIR (Methodology and Research in Surgery), valid for therapy studies and CONSORT (Consolidated Standards of Reporting Trials), valid for randomized controlled trials (RCT). Guides and scales were applied by 5 researchers with training in clinical epidemiology. The reader's guide verified that the Macdonald study was not directed to answer a clearly defined question. There was random assignment, but the method used is not described and the patients were not considered until the end of the study (36% of the group with surgery plus chemo radiotherapy did not complete treatment). MINCIR scale confirmed a multicentric RCT, not blinded, with an unclear randomized sequence, erroneous sample size estimation, vague objectives and no exclusion criteria. CONSORT system proved the lack of working hypothesis and specific objectives as well as an absence of exclusion criteria and identification of the primary variable, an imprecise estimation of sample size, ambiguities in the randomization process, no blinding, an absence of statistical adjustment and the omission of a subgroup analysis. The instruments applied demonstrated methodological shortcomings that compromise the internal and external validity of the.

Infantry Weapons Test METHODOLOGY Study. Volume 2. Antitank Weapons Test Methodology

DTIC Science & Technology

1972-01-17

the event of a hit so located (e..g., on the treads) as to disable a tank. A - I 14 AtIjj’ LA...which disable the tank’s guns. Guided Missile - An unmanned vohicle moving above the surface of the earth, whose trajectory or flight path is capable...attitude and well-being. People can be classed according to a need to achievje and the characteristics displayed by high-need achievers and low-need

Can nurse teachers manage student incivility by guided democracy? A grounded theory study.

PubMed

Rad, Mostafa; Karimi Moonaghi, Hossein; Ildarabadi, Eshagh

2017-07-17

Managing incivility in academic settings is among the basic concerns and challenges of most educational systems, including nursing education. Incivility management cannot be considered devoid of disruptive behaviors. However, incivility management is a complexphenomenon upon which few studies are conducted. The present study aims at discovering teachers and students' experiences regarding incivility and developing an approach to manage nursing students' incivility. The present study was conducted based on the qualitative research design of the grounded theory methodology. This study was conducted at schools of nursing in academic settings in Iran. Study participants in the present study include nurse teachers (N=20) and nursing students (N=9). In-depth semi-structured interviews were conducted using theoretical and purposive sampling. Constant comparative analysis was used for data analysis. The results include four main categories; (1) deterioration of learning; (2) dominant individual and organisational culture; (3) guided democracy; and (4) movement toward professionalism. Guided democracy is recognised as the main basic psychosocial process for incivility management. Incivility management is pursued to help learners develop professional performance. As indicated by the results of the present study, guided democracy is an effective strategy for incivility management in nursing education. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Evaluation of commercial nickel-phosphorus coating for ultracold neutron guides using a pinhole bottling method

DOE PAGES

Pattie. Jr., Robert Wayne; Adamek, Evan Robert; Brenner, Thomas; ...

2017-08-10

We report on the evaluation of commercial electroless nickel phosphorus (NiP) coatings for ultracold neutron (UCN) transport and storage. The material potential of 50μm thick NiP coatings on stainless steel and aluminum substrates was measured to be V F=213(5.2)neV using the time-of-flight spectrometer ASTERIX at the Lujan Center. The loss per bounce probability was measured in pinhole bottling experiments carried out at ultracold neutron sources at Los Alamos Neutron Science Center and the Institut Laue-Langevin. For these tests a new guide coupling design was used to minimize gaps between the guide sections. The observed UCN loss in the bottle wasmore » interpreted in terms of an energy independent effective loss per bounce, which is the appropriate model when gaps in the system and upscattering are the dominate loss mechanisms, yielding a loss per bounce of 1.3(1)×10 –4. In conclusion, we also present a detailed discussion of the pinhole bottling methodology and an energy dependent analysis of the experimental results.« less

Structural/aerodynamic Blade Analyzer (SAB) User's Guide, Version 1.0

NASA Technical Reports Server (NTRS)

Morel, M. R.

1994-01-01

The structural/aerodynamic blade (SAB) analyzer provides an automated tool for the static-deflection analysis of turbomachinery blades with aerodynamic and rotational loads. A structural code calculates a deflected blade shape using aerodynamic loads input. An aerodynamic solver computes aerodynamic loads using deflected blade shape input. The two programs are iterated automatically until deflections converge. Currently, SAB version 1.0 is interfaced with MSC/NASTRAN to perform the structural analysis and PROP3D to perform the aerodynamic analysis. This document serves as a guide for the operation of the SAB system with specific emphasis on its use at NASA Lewis Research Center (LeRC). This guide consists of six chapters: an introduction which gives a summary of SAB; SAB's methodology, component files, links, and interfaces; input/output file structure; setup and execution of the SAB files on the Cray computers; hints and tips to advise the user; and an example problem demonstrating the SAB process. In addition, four appendices are presented to define the different computer programs used within the SAB analyzer and describe the required input decks.

Evaluation of commercial nickel-phosphorus coating for ultracold neutron guides using a pinhole bottling method

NASA Astrophysics Data System (ADS)

Pattie, R. W.; Adamek, E. R.; Brenner, T.; Brandt, A.; Broussard, L. J.; Callahan, N. B.; Clayton, S. M.; Cude-Woods, C.; Currie, S. A.; Geltenbort, P.; Ito, T. M.; Lauer, T.; Liu, C. Y.; Majewski, J.; Makela, M.; Masuda, Y.; Morris, C. L.; Ramsey, J. C.; Salvat, D. J.; Saunders, A.; Schroffenegger, J.; Tang, Z.; Wei, W.; Wang, Z.; Watkins, E.; Young, A. R.; Zeck, B. A.

2017-11-01

We report on the evaluation of commercial electroless nickel phosphorus (NiP) coatings for ultracold neutron (UCN) transport and storage. The material potential of 50 μm thick NiP coatings on stainless steel and aluminum substrates was measured to be VF = 213(5 . 2) neV using the time-of-flight spectrometer ASTERIX at the Lujan Center. The loss per bounce probability was measured in pinhole bottling experiments carried out at ultracold neutron sources at Los Alamos Neutron Science Center and the Institut Laue-Langevin. For these tests a new guide coupling design was used to minimize gaps between the guide sections. The observed UCN loss in the bottle was interpreted in terms of an energy independent effective loss per bounce, which is the appropriate model when gaps in the system and upscattering are the dominate loss mechanisms, yielding a loss per bounce of 1 . 3(1) × 10-4. We also present a detailed discussion of the pinhole bottling methodology and an energy dependent analysis of the experimental results.

Evaluation of commercial nickel-phosphorus coating for ultracold neutron guides using a pinhole bottling method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pattie. Jr., Robert Wayne; Adamek, Evan Robert; Brenner, Thomas

We report on the evaluation of commercial electroless nickel phosphorus (NiP) coatings for ultracold neutron (UCN) transport and storage. The material potential of 50μm thick NiP coatings on stainless steel and aluminum substrates was measured to be V F=213(5.2)neV using the time-of-flight spectrometer ASTERIX at the Lujan Center. The loss per bounce probability was measured in pinhole bottling experiments carried out at ultracold neutron sources at Los Alamos Neutron Science Center and the Institut Laue-Langevin. For these tests a new guide coupling design was used to minimize gaps between the guide sections. The observed UCN loss in the bottle wasmore » interpreted in terms of an energy independent effective loss per bounce, which is the appropriate model when gaps in the system and upscattering are the dominate loss mechanisms, yielding a loss per bounce of 1.3(1)×10 –4. In conclusion, we also present a detailed discussion of the pinhole bottling methodology and an energy dependent analysis of the experimental results.« less

The economic evaluation of medical devices: challenges.

PubMed

Kingkaew, Pritaporn; Teerawattananon, Yot

2014-05-01

While many of the principles that guide the economic evaluation of medical devices are somewhat similar to those that guide the evaluation of other health technologies, most outline a methodology that focuses on pharmaceutical products rather providing specific guidance for medical devices. Given that medical devices use a wide range of technologies and can be used for many purposes, conducting an economic analysis for medical devices is not straightforward. The cost and effectiveness of a given technology may depend on a number of factors. The objective of this paper is to provide a summary of issues that need to be addressed before undertaking an economic evaluation of medical devices and to outline a number of suggested approaches for undertaking an economic evaluation of medical devices.

A guide to modelling cardiac electrical activity in anatomically detailed ventricles.

PubMed

Clayton, R H; Panfilov, A V

2008-01-01

One of the most recent trends in cardiac electrophysiology is the development of integrative anatomically accurate models of the heart, which include description of cardiac activity from sub-cellular and cellular level to the level of the whole organ. In order to construct this type of model, a researcher needs to collect a wide range of information from books and journal articles on various aspects of biology, physiology, electrophysiology, numerical mathematics and computer programming. The aim of this methodological article is to survey recent developments in integrative modelling of electrical activity in the ventricles of the heart, and to provide a practical guide to the resources and tools that are available for work in this exciting and challenging area.

Image-guided tissue engineering

PubMed Central

Ballyns, Jeffrey J; Bonassar, Lawrence J

2009-01-01

Replication of anatomic shape is a significant challenge in developing implants for regenerative medicine. This has lead to significant interest in using medical imaging techniques such as magnetic resonance imaging and computed tomography to design tissue engineered constructs. Implementation of medical imaging and computer aided design in combination with technologies for rapid prototyping of living implants enables the generation of highly reproducible constructs with spatial resolution up to 25 μm. In this paper, we review the medical imaging modalities available and a paradigm for choosing a particular imaging technique. We also present fabrication techniques and methodologies for producing cellular engineered constructs. Finally, we comment on future challenges involved with image guided tissue engineering and efforts to generate engineered constructs ready for implantation. PMID:19583811

Pain reduction and improvement of function following ultrasound-guided intra-articular injections of triamcinolone hexacetonide and hyaluronic acid in hip osteoarthritis.

PubMed

Araújo, J P; Silva, L; Andrade, R; Paços, M; Moreira, H; Migueis, N; Pereira, R; Sarmento, A; Pereira, H; Loureiro, N; Espregueira-Mendes, J

2016-01-01

The scientific literature has shown positive results regarding intra-articular injections of hyaluronic acid in osteoarthritic joints. When injecting in the hip joint, the guidance of ultrasound can provide higher injection accuracy and repeatability. However, due to the methodological limitations in the current available literature, its recommendation in the current practice is still controversial. This study shows that ultrasound-guided intra-articular injections of triamcinolone hexacetonide and hyaluronic acid can improve pain, function and quality of life in patients with symptomatic and radiographic hip osteoarthritis. In addition, the administration of triamcinolone hexacetonide and hyaluronic acid to the hip joint in these patients can delay the need for interventional surgery.

A person-centered approach to study intimacy and sexuality in residential care facility (RCF) clients with dementia: Methodological considerations and a guide to study design.

PubMed

Roelofs, Tineke S M; Luijkx, Katrien G; Embregts, Petri J C M

2017-01-01

The person-centered perspective of residential care facility (RCF) residents with dementia with regard to their intimate and sexual lives is largely neglected in research. We aim to provide methodological considerations and reflections on a performed qualitative study. Recommendations and a guide to study design are provided to inform and encourage future research on the inclusion of people with dementia as participants. Methodological recommendations and reflections are described in chronological order of the procedure. Fragments of interviews are included for further illustration and clarification. Considering preparation, close involvement of clinical practice, and extensive deliberation regarding study design tended to be important. Considering procedure, investment in contacts with clinical practice and authorized representatives; an introduction meeting; person-centered inclusion and consent; profound skills in interviewing participants with dementia; and flexibility in data collection were proven of importance. Considering data analysis and study quality, including field notes and aiming at a balance between study quality and practicability to enhance study 'rigor' were found important. Including the person-centered perspective in research on intimacy and sexuality of RCF residents with dementia, is challenging and takes a flexible and creative approach. It is, however, worthwhile to close the gap in literature.

75 FR 53169 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-45; Small Entity Compliance Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-30

... Contract Act, and trade agreements thresholds. The Councils have also used the same methodology to adjust... Business Regulatory Enforcement Fairness Act of 1996. It consists of a summary of rules appearing in...-008 Davis. and Reinvestment Act of 2009 (the Recovery Act)-- Buy American Requirements for...

Food Patterns Equivalents Database 2011-12: Methodology and User Guide

USDA-ARS?s Scientific Manuscript database

The purpose of developing the Food Patterns Equivalents Database (FPED) 2011-12 is to convert the 8,251 foods in the Food and Nutrients Database for Dietary Studies (FNDDS) 2011-12 used for the What We Eat in America, National Health and Nutrition Examination Survey (WWEIA, NHANES) 2011-12 to 37 USD...

Using the Outdoors to Enrich the Teaching of Mathematics.

ERIC Educational Resources Information Center

Payne, Milton R.

Written for teachers in elementary and middle schools and for personnel at outdoor education centers, this publication is the second in an ERIC/CRESS series on utilizing outdoor education methodologies to enhance the academic curriculum. The resource guide suggests ways of getting students interested in arithmetic and mathematics and how to make…

From California dreaming to California data: Challenging historic models for landfill CH4 emissions

USDA-ARS?s Scientific Manuscript database

Improved quantification of diverse CH4 sources at the urban scale is needed to guide local greenhouse gas (GHG) mitigation strategies in the Anthropocene. Herein, we focus on landfill CH4 emissions in California, challenging the current IPCC methodology which focuses on a climate dependency for land...

Using Video Surveillance Footage to Support Validity of Self-Reported Classroom Data

ERIC Educational Resources Information Center

Lee, Dabae; Arthur, Ian T.; Morrone, Anastasia S.

2017-01-01

The use of video surveillance footage presents a new possibility in educational research as a reliable and valid source of learning and teaching activities in classrooms. However, the unique nature of surveillance footage requires different approaches and poses distinctive challenges in utilizing it in research, yet no methodological guides are…

Recommendations for Writing Case Study Articles for Publication in the "Journal of College Counseling"

ERIC Educational Resources Information Center

Scholl, Mark B.

2017-01-01

The author presents recommendations for writing case studies for publication in the "Journal of College Counseling." Recommendations fall into 2 categories: (a) ethical considerations and (b) criteria essential to methodological rigor (e.g., Hyett, Kenny, & Dickson-Swift, 2014). The article is intended to guide and encourage…

Food Patterns Equivalents Database 2005-2006: Methodology and User Guide

USDA-ARS?s Scientific Manuscript database

The purpose of developing the Food Patterns Equivalents Database (FPED) 2005-2006 is to convert the 7,000+ foods in the Food and Nutrients Database for Dietary Studies (FNDDS) 3.0 used for the What We Eat in America, National Health and Nutrition Examination Survey (WWEIA, NHANES) 2005-2006, to USDA...

Experiences of Latino Couples in Relationship Education: A Critical Analysis

ERIC Educational Resources Information Center

Perez, Carlos; Brown, Matthew D.; Whiting, Jason B.; Harris, Steven M.

2013-01-01

There exists a need to better understand the applicability of Marriage and Relationship Education (MRE) initiatives with diverse populations. This study presents findings from focus groups with Latino men and women (N = 16) who participated in MRE classes. A critical theory approach guided the researchers who used grounded theory methodology to…

Using TV as a Guide: Associations between Television Viewing and Adolescents' Sexual Attitudes and Behavior

ERIC Educational Resources Information Center

Ward, L. Monique; Friedman, Kimberly

2006-01-01

Using both correlational and experimental methodology, this study examined contributions of TV viewing to adolescents' sexual attitudes and behavior. A sample of 244 high school students was assigned to view clips depicting either one of three sexual stereotypes or neutral content. Participants then completed measures assessing their attitudes…

Eye Tracking: A Brief Guide for Developmental Researchers

ERIC Educational Resources Information Center

Feng, Gary

2011-01-01

Eye tracking offers a powerful research tool for developmental scientists. In this brief article, the author introduces the methodology and issues associated with its applications in developmental research, beginning with an overview of eye movements and eye-tracking technologies, followed by examples of how it is used to study the developing mind…

Transforming the Economics Curriculum by Integrating Threshold Concepts

ERIC Educational Resources Information Center

Karunaratne, Prashan Shayanka Mendis; Breyer, Yvonne A.; Wood, Leigh N.

2016-01-01

Purpose: Economics is catering to a diverse student cohort. This cohort needs to be equipped with transformative concepts that students can integrate beyond university. When a curriculum is content-driven, threshold concepts are a useful tool in guiding curriculum re-design. The paper aims to discuss these issues. Design/Methodology/Approach: The…

A Review and Perspective on Lean in Higher Education

ERIC Educational Resources Information Center

Balzer, William K.; Francis, David E.; Krehbiel, Timothy C.; Shea, Nicholas

2016-01-01

Purpose: The purpose of this paper is to synthesize the accumulated body of research on Lean in higher education, draw conclusions to help guide successful Lean implementations and propose future research directions to establish a rich base of knowledge that informs both practice and research. Design/methodology/approach This literature review…

Ten Adaptive Strategies for Family and Work Balance: Advice from Successful Families.

ERIC Educational Resources Information Center

Haddock, Shelley A.; Zimmerman, Toni Schindler; Ziemba, Scott J.; Current, Lisa R.

2001-01-01

Investigated adaptive strategies of middle class, dual earner couples (N=47) with children that are successfully managing family and work. Guided by grounded-theory methodology, analysis of interview data revealed these successful couples structured their lives around 10 major strategies. Each strategy is defined and illustrated through the…

Mixed Methods Research: What Are the Key Issues to Consider?

ERIC Educational Resources Information Center

Ghosh, Rajashi

2016-01-01

Mixed methods research (MMR) is increasingly becoming a popular methodological approach in several fields due to the promise it holds for comprehensive understanding of complex problems being researched. However, researchers interested in MMR often lack reference to a guide that can explain the key issues pertaining to the paradigm wars…

Food Intakes Converted to Retail Commodities Databases 2003-08: Methodology and User Guide

USDA-ARS?s Scientific Manuscript database

The purpose for developing the Food Intakes Converted to Retail Commodities Databases (FICRCD) 2003-08 is to convert foods consumed in What We Eat In America, National Health and Nutrition Examination Survey (WWEIA, NHANES) 2003-2004, 2005-2006, and 2007-2008 to respective amounts of retail-level fo...

Evaluating Remote Reference Service: A Practical Guide to Problems and Solutions

ERIC Educational Resources Information Center

Pomerantz, Jeffrey; Mon, Lorri; McClure, Charles R.

2008-01-01

This paper identifies key methodological issues affecting quality of data in the evaluation of remote reference services. Despite a growing number of studies in this area, no comprehensive effort has been made to identify potential problems and suggest solutions. The strategies proposed in this paper offer practical ways in which libraries can…

Transition to Science Teacher Educator: Tensions Experienced While Learning to Teach Lesson Sequencing

ERIC Educational Resources Information Center

Wiebke, Heidi; Park Rogers, Meredith

2014-01-01

This self-study investigated the tensions that I (Heidi) encountered when teaching elementary preservice teachers how to develop a coherent sequence of five science lessons. Four lesson planning components guided me in developing a series of lessons to support the preservice teachers with this exercise. Employing self-study methodology, data…

Understanding Communities through the Eyes and Voices of Children

ERIC Educational Resources Information Center

Alaca, Betül; Rocca, Claudia; Maggi, Stefania

2017-01-01

The present study, guided by a child rights framework, aimed to gain insight into young children's perspectives of their communities and to explore the effectiveness of PhotoVoice methodology during this process. Thirty-two children aged three to five years from a childcare centre and a kindergarten classroom from an urban neighbourhood captured…

The Essential and Interrelated Components of Evidenced-Based IEPs: A User's Guide

ERIC Educational Resources Information Center

Hauser, Marc D.

2017-01-01

Individualized education program (IEP) goals and objectives often provide illogical or insufficient methodological detail (e.g., Capizzi, 2008). Insufficient methods can lead to ambiguity among the staff members responsible for data collection or to data that fail to take into account factors that can affect performance or behavioral expression…

Transforming Technocratic Practitioners' Thinking toward Responsible Management of Land-Related Conflicts: Experience from Eastern Ethiopia

ERIC Educational Resources Information Center

Hussein, Jeylan Wolyie; Bedasa, Nigusie Angessa

2017-01-01

The article presents analysis of the epistemological, pedagogical and methodological processes and dilemmas that unfolded during our efforts to transform the conceptions and understandings of our participants' thinking about ways of managing land-related conflicts. The paper reports our evaluation of the thinking and perspectives that guided our…

Assessing Customer Satisfaction at the NIST Research Library: Essential Tool for Future Planning

ERIC Educational Resources Information Center

Liu, Rosa; Allmang, Nancy

2008-01-01

This article describes a campus-wide customer satisfaction survey undertaken by the National Institute of Standards and Technology (NIST) Research Library in 2007. The methodology, survey instrument, data analysis, results, and actions taken in response to the survey are described. The outcome and recommendations will guide the library both…

Eco-Campus: Applying the Ecocity Model to Develop Green University and College Campuses

ERIC Educational Resources Information Center

Finlay, Jessica; Massey, Jennifer

2012-01-01

Purpose: The purpose of this paper is to argue that Richard Register's ecocity model offers a strategic framework to help guide sustainability initiatives in North American higher education (HE) institutions. Design/methodology/approach: This conceptual paper examines the theory of the ecocity and investigates the implications for its proposed…

A Different World: African American, First Generation College Women at a Selective University

ERIC Educational Resources Information Center

Johnson, Jennifer Michelle

2013-01-01

The purpose of this study was to gain a better understanding of the academic and social experiences of African American, first generation college students attending a selective university. Following interpretive case study methodology, the major research questions guiding this study were: How do African American, first generation college students…

Food Patterns Equivalents Database 2013-14: Methodology and User Guide

USDA-ARS?s Scientific Manuscript database

The purpose of developing the Food Patterns Equivalents Database (FPED) 2013-14 is to convert the 8,536 foods in the Food and Nutrients Database for Dietary Studies (FNDDS) 2013-14 used for the What We Eat in America, National Health and Nutrition Examination Survey (WWEIA, NHANES) 2013-14 to the 37...

Hui Students' Identity Construction in Eastern China: A Postcolonial Critique

ERIC Educational Resources Information Center

Wang, Yuxiang; Phillion, JoAnn

2011-01-01

In this article, we explored Hui students' lived experiences in school in eastern China and the impact of their experiences on their identity construction. We used postcolonial theory as a theoretical framework and narrative inquiry as a research methodology to guide questions that we asked, data collection, data analysis, and interpretation and…

Small Business Management. Instructor's Manual. Volume I. Third Edition.

ERIC Educational Resources Information Center

Jeanneau, Joseph A.; And Others

The instructor's manual is one of four prepared as a guide in conducting a small Business Management course for American Indians to prepare them for jobs as owners/managers of their own businesses and for management positions with business owned by bonds, cooperatives, and others. The manual contains lesson plans, suggested methodologies, and…

Tuning: A Guide for Creating Discipline-Specific Frameworks to Foster Meaningful Change

ERIC Educational Resources Information Center

Marshall, David W.

2017-01-01

Tuning, as a methodology, implies a philosophy of curriculum design, pedagogy, and assignment design. It implies that successful study in a discipline depends on intentional construction of learning experiences for students. Intentional construction of learning experiences requires an understanding of the learning goals set forth by faculty for…

Orbiter lessons learned: A guide to future vehicle development

NASA Technical Reports Server (NTRS)

Greenberg, Harry Stan

1993-01-01

Topics addressed are: (1) wind persistence loads methodology; (2) emphasize supportability in design of reusable vehicles; (3) design for robustness; (4) improved aerodynamic environment prediction methods for complex vehicles; (5) automated integration of aerothermal, manufacturing, and structures analysis; (6) continued electronic documentation of structural design and analysis; and (7) landing gear rollout load simulations.

Research Informing Practice--Practice Informing Research: Innovative Teaching Methologies for World Language Teachers. Research in Second Language Learning

ERIC Educational Resources Information Center

Schwarzer, David, Ed.; Petron, Mary, Ed.; Luke, Christopher, Ed.

2011-01-01

"Research Informing Practice--Practice Informing Research: Innovative Teaching Methodologies for World Language Educators" is an edited volume that focuses on innovative, nontraditional methods of teaching and learning world languages. Using teacher-research projects, each author in the volume guides readers through their own personal…

How Do Australian Junior Primary School Children Perceive the Concepts of "Healthy" and "Unhealthy?"

ERIC Educational Resources Information Center

Brindal, Emily; Hendrie, Gilly; Thompson, Kirrilly; Blunden, Sarah

2012-01-01

Purpose: This paper aims to describe Australian children's perceptions of healthiness and sources of health knowledge in order to develop an understanding of young children's perceptions, knowledge and sources of influence to guide future behaviour change and health promotion strategies. Design/methodology/approach: One-hour interactive focus…

Initial Teacher Education: Does Self-Efficacy Influence Candidate Teacher Academic Achievement and Future Career Performance?

ERIC Educational Resources Information Center

Shawer, Saad F.

2013-01-01

This quantitative investigation examined the influence of low and high self-efficacy on candidate teacher academic performance in a foreign language teaching methodology course through testing the speculation that high self-efficacy levels would improve pedagogical-content knowledge (PCK). Positivism guided the research design at the levels of…

Developing a Dissertation Research Problem: A Guide for Doctoral Students in Human Resource Development and Adult Education

ERIC Educational Resources Information Center

Jacobs, Ronald L.

2013-01-01

the need to state the problem of the study based on the scholarly literature. Doctoral programs commonly require that students take a sequence of research courses that usually focus on how to carry-out a study. That is, the design, the methodology, and the…

"Working with" as a Methodological Stance: Collaborating with Students in Teaching, Writing, and Research

ERIC Educational Resources Information Center

Siry, Christina A.; Zawatski, Elizabeth

2011-01-01

Using critical ethnography guided by cultural sociology, this paper examines the role of "co" in teacher education; coresearching, coteaching, and cogenerating dialogue. The authors are a pre-service teacher and a college instructor, and through our multiple perspectives and positionings, we explore how collaboration served to dismantle…

We Knew It All Along! Using Cognitive Science to Explain How Andragogy Works

ERIC Educational Resources Information Center

Hagen, Marcia; Park, Sunyoung

2016-01-01

Purpose: This paper aims to link recent findings in cognitive neuroscience to better understand how andragogically informed instructional practices impact cognition and learning. Design/Methodology/Approach: The research questions guiding the study is in what ways can the recent findings in cognitive neuroscience help to inform adult education…

Accounting for Success and Failure: A Discursive Psychological Approach to Sport Talk

ERIC Educational Resources Information Center

Locke, Abigail

2004-01-01

In recent years, constructionist methodologies such as discursive psychology (Edwards & Potter, 1992) have begun to be used in sport research. This paper provides a practical guide to applying a discursive psychological approach to sport data. It discusses the assumptions and principles of discursive psychology and outlines the stages of a…

Understanding, Embracing and Reflecting upon the Messiness of Doctoral Fieldwork

ERIC Educational Resources Information Center

Naveed, Arif; Sakata, Nozomi; Kefallinou, Anthoula; Young, Sara; Anand, Kusha

2017-01-01

This Forum issue discusses the centrality of the fieldwork in doctoral research. The inevitability of researchers' influence and of their values apparent during and after their fieldwork calls for a high degree of reflexivity. Since the standard methodology textbooks do not sufficiently guide on addressing such challenges, doctoral researchers go…

Future Language Teachers Learning to Become CALL Designers--Methodological Perspectives in Studying Complexity

ERIC Educational Resources Information Center

Keisanen, Tiina; Kuure, Leena

2015-01-01

Language teachers of the future, our current students, live in an increasingly technology-rich world. However, language students do not necessarily see their own digital practices as having relevance for guiding language learning. Research in the fields of CALL and language education more generally indicates that teaching practices change slowly…

The Nature of Peer Coaching: Definitions, Goals, Processes and Outcomes

ERIC Educational Resources Information Center

Hagen, Marcia S.; Bialek, Tani K.; Peterson, Shari L.

2017-01-01

Purpose: The purpose of this research is to create a definition of peer coaching using literature from various and disparate organizational and educational contexts. This research is intended to clarify what constitutes peer coaching overall, and guide the ever-growing practice of peer coaching. Design/methodology/approach: This research uses a…

A Collaborative Action Research Project towards Embedding ESD within the Higher Education Curriculum

ERIC Educational Resources Information Center

Cebrián, Gisela

2017-01-01

Purpose: This paper aims to present a collaborative action research project conducted at the University of Southampton with the aim to promote curriculum and professional development in education for sustainable development (ESD) and learn from everyday practices of academics. Design/methodology/approach: An action research approach guided by…

Modeling Cultural Context for Aspiring Women Educational Leaders

ERIC Educational Resources Information Center

Sperandio, Jill

2010-01-01

Purpose: The purpose of the paper is to discuss and examine the development of frameworks and models to guide future research into studies of women's paths to educational leadership worldwide. Design/methodology/approach: A grounded theory approach to the development of a model of the factors and their interaction that determine the path to…

A Practical Guide to the Teaching of English as a Second or Foreign Language.

ERIC Educational Resources Information Center

Rivers, Wilga M.; Temperley, Mary S.

This text, designed for future teachers of English as a second or foreign language, considers language teaching methodology in the light of recent research in psychology and linguistics. Many aspects of language learning that contribute to effective language use are discussed: oral communication, pronunciation, grammar instruction, listening…

Understanding Effective High Schools: Evidence for Personalization for Academic and Social Emotional Learning

ERIC Educational Resources Information Center

Rutledge, Stacey A.; Cohen-Vogel, Lora; Osborne-Lampkin, La'Tara; Roberts, Ronnie L.

2015-01-01

This article presents findings from a year-long multilevel comparative case study exploring the characteristics of effective urban high schools. We developed a comprehensive framework from the school effectiveness research that guided our data collection and analysis at the four high schools. Using value-added methodology, we identified two higher…

Integrating Action and Reflection through Co-operative Inquiry.

ERIC Educational Resources Information Center

Reason, Peter

1999-01-01

Defines co-operative inquiry as a radically participative form of inquiry in which all involved are both co-researchers and co-subjects. Introduces methodology in a layperson's guide. Reflects on the learning process of an inquiry group, especially the process of research cycling, importance of peer group, and the paradoxical self-reflexive…

Online Learning Tools for Middle School Science: Lessons Learned from a Design-Based Research Project

ERIC Educational Resources Information Center

Terrazas-Arellanes, Fatima E.; Knox, Carolyn; Strycker, Lisa A.; Walden, Emily D.

2017-01-01

This article reports on how design-based research methodology was used to guide a line of intervention research that developed, implemented, revised, and evaluated online learning science curricula for middle school students, including general education students and English language learners (primarily of Hispanic origin). The iterative,…

Advanced Endoscopic Navigation: Surgical Big Data, Methodology, and Applications.

PubMed

Luo, Xiongbiao; Mori, Kensaku; Peters, Terry M

2018-06-04

Interventional endoscopy (e.g., bronchoscopy, colonoscopy, laparoscopy, cystoscopy) is a widely performed procedure that involves either diagnosis of suspicious lesions or guidance for minimally invasive surgery in a variety of organs within the body cavity. Endoscopy may also be used to guide the introduction of certain items (e.g., stents) into the body. Endoscopic navigation systems seek to integrate big data with multimodal information (e.g., computed tomography, magnetic resonance images, endoscopic video sequences, ultrasound images, external trackers) relative to the patient's anatomy, control the movement of medical endoscopes and surgical tools, and guide the surgeon's actions during endoscopic interventions. Nevertheless, it remains challenging to realize the next generation of context-aware navigated endoscopy. This review presents a broad survey of various aspects of endoscopic navigation, particularly with respect to the development of endoscopic navigation techniques. First, we investigate big data with multimodal information involved in endoscopic navigation. Next, we focus on numerous methodologies used for endoscopic navigation. We then review different endoscopic procedures in clinical applications. Finally, we discuss novel techniques and promising directions for the development of endoscopic navigation.

Tools, strategies and qualitative approach in relation to suicidal attempts and ideation in the elderly.

PubMed

Cavalcante, Fátima Gonçalves; Minayo, Maria Cecília de Souza; Gutierrez, Denise Machado Duran; de Sousa, Girliani Silva; da Silva, Raimunda Magalhães; Moura, Rosylaine; Meneghel, Stela Nazareth; Grubits, Sonia; Conte, Marta; Cavalcante, Ana Célia Sousa; Figueiredo, Ana Elisa Bastos; Mangas, Raimunda Matilde do Nascimento; Fachola, María Cristina Heuguerot; Izquierdo, Giovane Mendieta

2015-06-01

The article analyses the quality and consistency of a comprehensive interview guide, adapted to study attempted suicide and its ideation among the elderly, and imparts the method followed in applying this tool. The objective is to show how the use of a semi-structured interview and the organization and data analysis set-up were tested and perfected by a network of researchers from twelve universities or research centers in Brazil, Uruguay and Colombia. The method involved application and evaluation of the tool and joint production of an instruction manual on data collection, systematization and analysis. The methodology was followed in 67 interviews with elderly people of 60 or older and in 34 interviews with health professionals in thirteen Brazilian municipalities and in Montevideo and Bogotá, allowing the consistency of the tool and the applicability of the method to be checked, during the process and at the end. The enhanced guide and the instructions for reproducing it are presented herein. The results indicate the suitability and credibility of this methodological approach, tested and certified in interdisciplinary and interinstitutional terms.

Optimization of Residual Stresses in MMC's Using Compensating/Compliant Interfacial Layers. Part 2: OPTCOMP User's Guide

NASA Technical Reports Server (NTRS)

Pindera, Marek-Jerzy; Salzar, Robert S.; Williams, Todd O.

1994-01-01

A user's guide for the computer program OPTCOMP is presented in this report. This program provides a capability to optimize the fabrication or service-induced residual stresses in uni-directional metal matrix composites subjected to combined thermo-mechanical axisymmetric loading using compensating or compliant layers at the fiber/matrix interface. The user specifies the architecture and the initial material parameters of the interfacial region, which can be either elastic or elastoplastic, and defines the design variables, together with the objective function, the associated constraints and the loading history through a user-friendly data input interface. The optimization procedure is based on an efficient solution methodology for the elastoplastic response of an arbitrarily layered multiple concentric cylinder model that is coupled to the commercial optimization package DOT. The solution methodology for the arbitrarily layered cylinder is based on the local-global stiffness matrix formulation and Mendelson's iterative technique of successive elastic solutions developed for elastoplastic boundary-value problems. The optimization algorithm employed in DOT is based on the method of feasible directions.

A methodology to guide the selection of composite materials in a wind turbine rotor blade design process

NASA Astrophysics Data System (ADS)

Bortolotti, P.; Adolphs, G.; Bottasso, C. L.

2016-09-01

This work is concerned with the development of an optimization methodology for the composite materials used in wind turbine blades. Goal of the approach is to guide designers in the selection of the different materials of the blade, while providing indications to composite manufacturers on optimal trade-offs between mechanical properties and material costs. The method works by using a parametric material model, and including its free parameters amongst the design variables of a multi-disciplinary wind turbine optimization procedure. The proposed method is tested on the structural redesign of a conceptual 10 MW wind turbine blade, its spar caps and shell skin laminates being subjected to optimization. The procedure identifies a blade optimum for a new spar cap laminate characterized by a higher longitudinal Young's modulus and higher cost than the initial one, which however in turn induce both cost and mass savings in the blade. In terms of shell skin, the adoption of a laminate with intermediate properties between a bi-axial one and a tri-axial one also leads to slight structural improvements.

High-Resolution Ultrasound Imaging Using Model-Bases Iterative Reconstruction For Canister Degradation Detection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chatzidakis, Stylianos; Jarrell, Joshua J; Scaglione, John M

The inspection of the dry storage canisters that house spent nuclear fuel is an important issue facing the nuclear industry; currently, there are limited options available to provide for even minimal inspections. An issue of concern is stress corrosion cracking (SCC) in austenitic stainless steel canisters. SCC is difficult to predict and exhibits small crack opening displacements on the order of 15 30 m. Nondestructive examination (NDE) of such microscopic cracks is especially challenging, and it may be possible to miss SCC during inspections. The coarse grain microstructure at the heat affected zone reduces the achievable sensitivity of conventional ultrasoundmore » techniques. At Oak Ridge National Laboratory, a tomographic approach is under development to improve SCC detection using ultrasound guided waves and model-based iterative reconstruction (MBIR). Ultrasound-guided waves propagate parallel to the physical boundaries of the surface and allow for rapid inspection of a large area from a single probe location. MBIR is a novel, effective probabilistic imaging tool that offers higher precision and better image quality than current reconstruction techniques. This paper analyzes the canister environment, stainless steel microstructure, and SCC characteristics. The end goal is to demonstrate the feasibility of an NDE system based on ultrasonic guided waves and MBIR for canister degradation and to produce radar-like images of the canister surface with significantly improved image quality. The proposed methodology can potentially reduce human radiation exposure, result in lower operational costs, and provide a methodology that can be used to verify canister integrity in-situ during extended storage« less

Application of the Navigation Guide systematic review methodology to the evidence for developmental and reproductive toxicity of triclosan.

PubMed

Johnson, Paula I; Koustas, Erica; Vesterinen, Hanna M; Sutton, Patrice; Atchley, Dylan S; Kim, Allegra N; Campbell, Marlissa; Donald, James M; Sen, Saunak; Bero, Lisa; Zeise, Lauren; Woodruff, Tracey J

2016-01-01

There are reports of developmental and reproductive health effects associated with the widely used biocide triclosan. Apply the Navigation Guide systematic review methodology to answer the question: Does exposure to triclosan have adverse effects on human development or reproduction? We applied the first 3 steps of the Navigation Guide methodology: 1) Specify a study question, 2) Select the evidence, and 3) Rate quality and strength of the evidence. We developed a protocol, conducted a comprehensive search of the literature, and identified relevant studies using pre-specified criteria. We assessed the number and type of all relevant studies. We evaluated each included study for risk of bias and rated the quality and strength of the evidence for the selected outcomes. We conducted a meta-analysis on a subset of suitable data. We found 4282 potentially relevant records, and 81 records met our inclusion criteria. Of the more than 100 endpoints identified by our search, we focused our evaluation on hormone concentration outcomes, which had the largest human and non-human mammalian data set. Three human studies and 8 studies conducted in rats reported thyroxine levels as outcomes. The rat data were amenable to meta-analysis. Because only one of the human thyroxine studies quantified exposure, we did not conduct a meta-analysis of the human data. Through meta-analysis of the data for rats, we estimated for prenatal exposure a 0.09% (95% CI: -0.20, 0.02) reduction in thyroxine concentration per mg triclosan/kg-bw in fetal and young rats compared to control. For postnatal exposure we estimated a 0.31% (95% CI: -0.38, -0.23) reduction in thyroxine per mg triclosan/kg-bw, also compared to control. Overall, we found low to moderate risk of bias across the human studies and moderate to high risk of bias across the non-human studies, and assigned a "moderate/low" quality rating to the body of evidence for human thyroid hormone alterations and a "moderate" quality rating to the body of evidence for non-human thyroid hormone alterations. Based on this application of the Navigation Guide systematic review methodology, we concluded that there was "sufficient" non-human evidence and "inadequate" human evidence of an association between triclosan exposure and thyroxine concentrations, and consequently, triclosan is "possibly toxic" to reproductive and developmental health. Thyroid hormone disruption is an upstream indicator of developmental toxicity. Additional endpoints may be identified as being of equal or greater concern as other data are developed or evaluated. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Application of the Navigation Guide Systematic Review Methodology to the Evidence for Developmental and Reproductive Toxicity of Triclosan

PubMed Central

Johnson, Paula I.; Koustas, Erica; Vesterinen, Hanna M.; Sutton, Patrice; Atchley, Dylan S.; Kim, Allegra N.; Campbell, Marlissa; Donald, James M.; Sen, Saunak; Bero, Lisa; Zeise, Lauren; Woodruff, Tracey J.

2016-01-01

Background There are reports of developmental and reproductive health effects associated with the widely used biocide triclosan. Objective Apply the Navigation Guide systematic review methodology to answer the question: Does exposure to triclosan have adverse effects on human development or reproduction? Methods We applied the first 3 steps of the Navigation Guide methodology: 1) Specify a study question, 2) Select the evidence, and 3) Rate quality and strength of the evidence. We developed a protocol, conducted a comprehensive search of the literature, and identified relevant studies using pre-specified criteria. We assessed the number and type of all relevant studies. We evaluated each included study for risk of bias and rated the quality and strength of the evidence for the selected outcomes. We conducted a meta-analysis on a subset of suitable data. Results We found 4,282 potentially relevant records, and 81 records met our inclusion criteria. Of the more than 100 endpoints identified by our search, we focused our evaluation on hormone concentration outcomes, which had the largest human and non-human mammalian data set. Three human studies and 8 studies conducted in rats reported thyroxine levels as outcomes. The rat data were amenable to meta-analysis. Because only one of the human thyroxine studies quantified exposure, we did not conduct a meta-analysis of the human data. Through meta-analysis of the data for rats, we estimated for prenatal exposure a 0.09% (95% CI: −0.20, 0.02) reduction in thyroxine concentration per mg triclosan/kg-bw in fetal and young rats compared to control. For postnatal exposure we estimated a 0.31% (95% CI: −0.38, −0.23) reduction in thyroxine per mg triclosan/kg-bw, also compared to control. Overall we found low to moderate risk of bias across the human studies and moderate to high risk of bias across the non-human studies, and assigned a “moderate/low” quality rating to the body of evidence for human thyroid hormone alterations and a “moderate” quality rating to the body of evidence for non-human thyroid hormone alterations. Conclusion Based on this application of the Navigation Guide systematic review methodology, we concluded that there was “sufficient” non-human evidence and “inadequate” human evidence of an association between triclosan exposure and thyroxine concentrations, and consequently, triclosan is “possibly toxic” to reproductive and developmental health. Thyroid hormone disruption is an upstream indicator of developmental toxicity. Additional endpoints may be identified as being of equal or greater concern as other data are developed or evaluated. PMID:27156197

Exoplanet Biosignatures: Future Directions

PubMed Central

Bains, William; Cronin, Leroy; DasSarma, Shiladitya; Danielache, Sebastian; Domagal-Goldman, Shawn; Kacar, Betul; Kiang, Nancy Y.; Lenardic, Adrian; Reinhard, Christopher T.; Moore, William; Schwieterman, Edward W.; Shkolnik, Evgenya L.; Smith, Harrison B.

2018-01-01

Abstract We introduce a Bayesian method for guiding future directions for detection of life on exoplanets. We describe empirical and theoretical work necessary to place constraints on the relevant likelihoods, including those emerging from better understanding stellar environment, planetary climate and geophysics, geochemical cycling, the universalities of physics and chemistry, the contingencies of evolutionary history, the properties of life as an emergent complex system, and the mechanisms driving the emergence of life. We provide examples for how the Bayesian formalism could guide future search strategies, including determining observations to prioritize or deciding between targeted searches or larger lower resolution surveys to generate ensemble statistics and address how a Bayesian methodology could constrain the prior probability of life with or without a positive detection. Key Words: Exoplanets—Biosignatures—Life detection—Bayesian analysis. Astrobiology 18, 779–824. PMID:29938538

Exoplanet Biosignatures: Future Directions.

PubMed

Walker, Sara I; Bains, William; Cronin, Leroy; DasSarma, Shiladitya; Danielache, Sebastian; Domagal-Goldman, Shawn; Kacar, Betul; Kiang, Nancy Y; Lenardic, Adrian; Reinhard, Christopher T; Moore, William; Schwieterman, Edward W; Shkolnik, Evgenya L; Smith, Harrison B

2018-06-01

We introduce a Bayesian method for guiding future directions for detection of life on exoplanets. We describe empirical and theoretical work necessary to place constraints on the relevant likelihoods, including those emerging from better understanding stellar environment, planetary climate and geophysics, geochemical cycling, the universalities of physics and chemistry, the contingencies of evolutionary history, the properties of life as an emergent complex system, and the mechanisms driving the emergence of life. We provide examples for how the Bayesian formalism could guide future search strategies, including determining observations to prioritize or deciding between targeted searches or larger lower resolution surveys to generate ensemble statistics and address how a Bayesian methodology could constrain the prior probability of life with or without a positive detection. Key Words: Exoplanets-Biosignatures-Life detection-Bayesian analysis. Astrobiology 18, 779-824.

Technical Note: Error metrics for estimating the accuracy of needle/instrument placement during transperineal magnetic resonance/ultrasound-guided prostate interventions.

PubMed

Bonmati, Ester; Hu, Yipeng; Villarini, Barbara; Rodell, Rachael; Martin, Paul; Han, Lianghao; Donaldson, Ian; Ahmed, Hashim U; Moore, Caroline M; Emberton, Mark; Barratt, Dean C

2018-04-01

Image-guided systems that fuse magnetic resonance imaging (MRI) with three-dimensional (3D) ultrasound (US) images for performing targeted prostate needle biopsy and minimally invasive treatments for prostate cancer are of increasing clinical interest. To date, a wide range of different accuracy estimation procedures and error metrics have been reported, which makes comparing the performance of different systems difficult. A set of nine measures are presented to assess the accuracy of MRI-US image registration, needle positioning, needle guidance, and overall system error, with the aim of providing a methodology for estimating the accuracy of instrument placement using a MR/US-guided transperineal approach. Using the SmartTarget fusion system, an MRI-US image alignment error was determined to be 2.0 ± 1.0 mm (mean ± SD), and an overall system instrument targeting error of 3.0 ± 1.2 mm. Three needle deployments for each target phantom lesion was found to result in a 100% lesion hit rate and a median predicted cancer core length of 5.2 mm. The application of a comprehensive, unbiased validation assessment for MR/US guided systems can provide useful information on system performance for quality assurance and system comparison. Furthermore, such an analysis can be helpful in identifying relationships between these errors, providing insight into the technical behavior of these systems. © 2018 American Association of Physicists in Medicine.

Petroleum Refinery Jobs and Economic Development Impact (JEDI) Model User Reference Guide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldberg, Marshall

The Jobs and Economic Development Impact (JEDI) models, developed through the National Renewable Energy Laboratory (NREL), are user-friendly tools utilized to estimate the economic impacts at the local level of constructing and operating fuel and power generation projects for a range of conventional and renewable energy technologies. The JEDI Petroleum Refinery Model User Reference Guide was developed to assist users in employing and understanding the model. This guide provides information on the model's underlying methodology, as well as the parameters and references used to develop the cost data utilized in the model. This guide also provides basic instruction on modelmore » add-in features, operation of the model, and a discussion of how the results should be interpreted. Based on project-specific inputs from the user, the model estimates job creation, earning and output (total economic activity) for a given petroleum refinery. This includes the direct, indirect and induced economic impacts to the local economy associated with the refinery's construction and operation phases. Project cost and job data used in the model are derived from the most current cost estimations available. Local direct and indirect economic impacts are estimated using economic multipliers derived from IMPLAN software. By determining the regional economic impacts and job creation for a proposed refinery, the JEDI Petroleum Refinery model can be used to field questions about the added value refineries may bring to the local community.« less

Standards and guidelines for biopolymers in tissue-engineered medical products: ASTM alginate and chitosan standard guides. American Society for Testing and Materials.

PubMed

Dornish, M; Kaplan, D; Skaugrud, O

2001-11-01

The American Society for Testing and Materials (ASTM) is making a concerted effort to establish standards and guidelines for the entire field of tissue-engineered medical products (TEMPS). Safety, consistency, and functionality of biomaterials used as matrices, scaffolds, and immobilizing agents in TEMPS are a concern. Therefore, the ASTM has established a number of task groups to produce standards and guidelines for such biomaterials. Alginate is a naturally occurring biomaterial used for immobilizing living cells to form an artificial organ, such as encapsulated pancreatic islets. In order to aid in successful clinical applications and to help expedite regulatory approval, the alginate used must be fully documented. The ASTM alginate guide gives information on selection of testing methodologies and safety criteria. Critical parameters such as monomer content, molecular weight, and viscosity, in addition to more general parameters, such as dry matter content, heavy metal content, bioburden, and endotoxin content are described in the ASTM document. In a like manner, the characterization parameters for chitosan, a bioadhesive polycationic polysaccharide, are described in a separate guide. For chitosan, the degree of deacetylation is of critical importance. Control of protein content and, hence, potential for hypersensitivity, endotoxin content, and total bioburden are important in chitosan preparations for TEMPS. Together these two guides represent part of the effort on behalf of the ASTM and other interested parties to ensure quality and standardization in TEMPS.

Globe Teachers Guide and Photographic Data on the Web

NASA Technical Reports Server (NTRS)

Kowal, Dan

2004-01-01

The task of managing the GLOBE Online Teacher s Guide during this time period focused on transforming the technology behind the delivery system of this document. The web application transformed from a flat file retrieval system to a dynamic database access approach. The new methodology utilizes Java Server Pages (JSP) on the front-end and an Oracle relational database on the backend. This new approach allows users of the web site, mainly teachers, to access content efficiently by grade level and/or by investigation or educational concept area. Moreover, teachers can gain easier access to data sheets and lab and field guides. The new online guide also included updated content for all GLOBE protocols. The GLOBE web management team was given documentation for maintaining the new application. Instructions for modifying the JSP templates and managing database content were included in this document. It was delivered to the team by the end of October, 2003. The National Geophysical Data Center (NGDC) continued to manage the school study site photos on the GLOBE website. 333 study site photo images were added to the GLOBE database and posted on the web during this same time period for 64 schools. Documentation for processing study site photos was also delivered to the new GLOBE web management team. Lastly, assistance was provided in transferring reference applications such as the Cloud and LandSat quizzes and Earth Systems Online Poster from NGDC servers to GLOBE servers along with documentation for maintaining these applications.

7 CFR 1942.20 - Community Facility Guides.

Code of Federal Regulations, 2011 CFR

2011-01-01

.... (7) Guide 7—Preliminary Engineering Report Water Facility. (8) Guide 8—Preliminary Engineering Report Sewerage Systems. (9) Guide 9—Preliminary Engineering Report Solid Waste Disposal Systems. (10) Guide 10—Preliminary Engineering Report Storm Waste-Water Disposal. (11) Guide 11—Daily Inspection Report. (12) Guide...

"Re"storying the Present by "Re"visiting the Past: Unexpected Moments of Discovery and Illumination through Museum Learning

ERIC Educational Resources Information Center

Kawalilak, Colleen; Groen, Janet

2016-01-01

Two adult educators, guided by autoethnography as methodology, share the restorying of their own lifelong learning narratives and unexpected insights gained from having experienced the powerful potential of museum learning and culture. Having previously regarded museum visits as an experience that primarily tapped the intellectual, cognitive…

The Development of Talent in Young Adults with Williams Syndrome: An Exploratory Study of Ecological Influences

ERIC Educational Resources Information Center

Milne, Harry

2004-01-01

This mixed methods study employed comparative, case-study methodology to explore influences affecting the development of musical interests and achievements in eight female and eight male young adults with Williams Syndrome. Components of the "Schoolwide Enrichment Model"; (Renzulli & Reis, 1997b) were used to guide the study. Caregivers completed…

Helping Spanish SMEs Staff to Develop Their Competence in Writing Business Letters

ERIC Educational Resources Information Center

Foz-Gil, Carmen; Gonzalez-Pueyo, Isabel

2009-01-01

This paper reports on the development of a website tool aimed at helping Spanish small and medium enterprises (SMEs) staff to write their commercial correspondence in English. It describes the steps involved in the tool system design process, making an emphasis on the methodological criteria and rational that guided us to develop the site. In…

Measuring fuel moisture content in Alaska: standard methods and procedures.

Treesearch

Rodney A. Norum; Melanie Miller

1984-01-01

Methods and procedures are given for collecting and processing living and dead plant materials for the purpose of determining their water content. Wild-land fuels in Alaska are emphasized, but the methodology is applicable elsewhere. Guides are given for determining the number of samples needed to attain a chosen precision. Detailed procedures are presented for...

Practicing Learner-Centered Teaching: Pedagogical Design and Assessment of a Second Life Project

ERIC Educational Resources Information Center

Schiller, Shu Z.

2009-01-01

Guided by the principles of learner-centered teaching methodology, a Second Life project is designed to engage students in active learning of virtual commerce through hands-on experiences and teamwork in a virtual environment. More importantly, an assessment framework is proposed to evaluate the learning objectives and learning process of the…

Critical Factors Affecting Students' Satisfaction with Higher Education in Sri Lanka

ERIC Educational Resources Information Center

Weerasinghe, I. M. S.; Fernando, R. L. S.

2018-01-01

Purpose: The purpose of this study is to explain critical factors affecting student satisfaction levels in selected state universities in Sri Lanka. Design/methodology/approach: The study has applied an quantitative survey design guided by six hypotheses. A conceptual framework has been developed to address the research questions on the basis of a…

Radio telemetry methods for studying spotted owls in the Pacific Northwest.

Treesearch

J.H. Guetterman; J.A. Burns; J.A. Reid; R.B. Horn; C.C. Foster

1991-01-01

The paper is a practical guide to field methodology for conducting a radio telemetry study of spotted owls (Strix occidentalis) in mountainous terrain. It begins with a synopsis of spotted owl biology and basic telemetry. The criteria used to select which owls will carry transmitters are discussed as are location and capture methods. Instructions...

Core Journals in Library and Information Science: Developing a Methodology for Ranking LIS Journals

ERIC Educational Resources Information Center

Nixon, Judith M.

2014-01-01

In the library science field, there is no professionally accepted tiered list of journals in the United States to guide librarians, as there is in other academic disciplines. This situation creates a challenge for both new and experienced librarians who wish to make a serious contribution to librarianship by publishing articles. This article…

Empirically Guided Coordination of Multiple Evidence-Based Treatments: An Illustration of Relevance Mapping in Children's Mental Health Services

ERIC Educational Resources Information Center

Chorpita, Bruce F.; Bernstein, Adam; Daleiden, Eric L.

2011-01-01

Objective: Despite substantial progress in the development and identification of psychosocial evidence-based treatments (EBTs) in mental health, there is minimal empirical guidance for selecting an optimal "set" of EBTs maximally applicable and generalizable to a chosen service sample. Relevance mapping is a proposed methodology that…

Land Treatment. Instructor Guide. Working for Clean Water: An Information Program for Advisory Committees

ERIC Educational Resources Information Center

Pennsylvania State Univ., Middletown. Inst. of State and Regional Affairs.

Presented is an instructor's manual for a learning session centered on the methodology and feasibility of land treatment of municipal wastewater. A supplementary slide-tape program is available. These materials are components of the Working for Clean Water Project, which is intended to educate advisory groups who are interested in improving…

Applying Case-Based Method in Designing Self-Directed Online Instruction: A Formative Research Study

ERIC Educational Resources Information Center

Luo, Heng; Koszalka, Tiffany A.; Arnone, Marilyn P.; Choi, Ikseon

2018-01-01

This study investigated the case-based method (CBM) instructional-design theory and its application in designing self-directed online instruction. The purpose of this study was to validate and refine the theory for a self-directed online instruction context. Guided by formative research methodology, this study first developed an online tutorial…

A Methodological Study of a Computer-Managed Instructional Program in High School Physics.

ERIC Educational Resources Information Center

Denton, Jon James

The purpose of this study was to develop and evaluate an instructional model which utilized the computer to produce individually prescribed instructional guides in physics at the secondary school level. The sample consisted of three classes. Of these, two were randomly selected to serve as the treatment groups, e.g., individualized instruction and…

Guiding the Development and Use of Cost-Effectiveness Analysis in Education

ERIC Educational Resources Information Center

Levin, Henry M.; Belfield, Clive

2015-01-01

Cost-effectiveness analysis is rarely used in education. When it is used, it often fails to meet methodological standards, especially with regard to cost measurement. Although there are occasional criticisms of these failings, we believe that it is useful to provide a listing of the more common concerns and how they might be addressed. Based upon…

Assessing copper pinhole leaks in residential plumbing.

PubMed

Edwards, M; Rushing, J C; Kvech, S; Reiber, S

2004-01-01

Pinhole leaks in copper tubes are a major problem for homeowners, and an aggressive conscientious effort by utilities is recommended to diagnose the problem and identify potential solutions. In a case study at one utility, pinhole leak frequency data was compiled and a methodology was followed that might prove to be a useful guide for those facing similar problems.

Measuring the Impact of University Technology Transfer: A Guide to Methodologies, Data Needs, and Sources

ERIC Educational Resources Information Center

Lowe, Robert A.; Quick, Suzanne K.

2005-01-01

This paper discusses measures that capture the impact of university technology transfer activities on a university?s local and regional economies (economic impact). Such assessments are of increasing interest to policy makers, researchers and technology transfer professionals, yet there have been few published discussions of the merits of various…

New York City's Children First Networks: Turning Accountability on Its Head

ERIC Educational Resources Information Center

Wohlstetter, Priscilla; Smith, Joanna; Gallagher, Andrew

2013-01-01

Purpose: The purpose of this paper is to report findings from an exploratory study of New York's Children First Networks (CFNs); to examine what is known about the CFNs thus far, drawing on new empirical research, as well as document review and analysis of secondary sources. Design/methodology/approach: Organizational learning theory guided this…

Mixed methods research.

PubMed

Halcomb, Elizabeth; Hickman, Louise

2015-04-08

Mixed methods research involves the use of qualitative and quantitative data in a single research project. It represents an alternative methodological approach, combining qualitative and quantitative research approaches, which enables nurse researchers to explore complex phenomena in detail. This article provides a practical overview of mixed methods research and its application in nursing, to guide the novice researcher considering a mixed methods research project.

How to Develop Children as Researchers: A Step-by-Step Guide to Teaching the Research Process

ERIC Educational Resources Information Center

Kellett, Mary

2005-01-01

The importance of research in professional and personal development is increasingly being acknowledged. So why should children not benefit in a similar way? Traditionally, children have been excluded from this learning process because research methodology is considered too difficult for them. Principal obstacles focus around three key barriers:…

Development of a Methodology to Guide the Replacement of Agency Default Uncertainty Factors with Those Based on Data

EPA Science Inventory

The Agency's guidance for the derivation of RfD and RfC values call for the downward adjustment of exposure-response levels observed in animals and/or humans to account for the potentially greater sensitivity of humans as compared to test animals (UFA) and the differential sensit...

Health Promotion Guidance Activity of Youth Sports Clubs

ERIC Educational Resources Information Center

Kokko, Sami; Kannas, Lasse; Villberg, Jari; Ormshaw, Michael

2011-01-01

Purpose: This paper aims to clarify the extent to which youth sports clubs guide their coaches to recognise health promotion as a part of the coaching practice. The guidance activity of clubs is seen parallel to internal organisational communication. Design/methodology/approach: A survey of 93 (from 120, 78 per cent) youth sports clubs in Finland…

Transforming English Language Learners' Work Readiness: Case Studies in Explicit, Work-Specific Vocabulary Instruction

ERIC Educational Resources Information Center

Madrigal-Hopes, Diana L.; Villavicencio, Edna; Foote, Martha M.; Green, Chris

2014-01-01

This qualitative study examined the impact of a six-step framework for work-specific vocabulary instruction in adult English language learners (ELLs). Guided by research in English as a second language (ESL) methodology and the transactional theory, the researchers sought to unveil how these processes supported the acquisition and application of…

Academic Resilience and Achievement: Self-Motivational Resources That Guide Faculty Participation in Instructional Technology Training at a Mexican University

ERIC Educational Resources Information Center

Montero-Hernandez, Virginia; Levin, John; Diaz-Castillo, Maribel

2014-01-01

This study uses narrative analysis to understand the ways in which Mexican university faculty members used their self-motivational resources to persist in an instructional technology training program within adverse work conditions. The methodology included interviews and participant observation. Findings suggest that faculty's academic resilience…

The Use of Rainfall Forecasts as a Decision Guide for Small-Scale Farming in Limpopo Province, South Africa

ERIC Educational Resources Information Center

Moeletsi, M. E.; Mellaart, E. A. R.; Mpandeli, N. S.; Hamandawana, H.

2013-01-01

Purpose: New innovative ways of communicating agrometeorological information are needed to help farmers, especially subsistence/small-scale farmers, to cope with the high climate variability experienced in most parts of southern Africa. Design/methodology/approach: The article introduces an early warning system for farmers. It utilizes short…

Qualitative Research: Theory, Method and Practice David Silverman Qualitative Research: Theory, Method and Practice Sage 390 £21.99 0761949348 0761949348 [Formula: see text].

PubMed

2005-04-01

This book represents an extensive revision and updating of the 1997 first edition. It includes five new chapters commissioned for this volume. It is intended to be a comprehensive but accessible guide to 'a variety of methodological approaches to qualitative research'.

School Leadership and Its Impact on Student Achievement: The Mediating Role of School Climate and Teacher Job Satisfaction

ERIC Educational Resources Information Center

Dutta, Vartika; Sahney, Sangeeta

2016-01-01

Purpose: The purpose of this paper is to examine the role of teacher job satisfaction and school climate in mediating the relative effects of principals' instructional and transformational leadership practices on student outcomes. Design/methodology/approach: Guided by strong evidence from theories on school leadership and work psychology, the…

Layering Networked and Symphonic Selves: A Critical Role for e-Portfolios in Employability through Integrative Learning

ERIC Educational Resources Information Center

Cambridge, Darren

2008-01-01

Purpose: E-portfolios, which document and facilitate learning and performance, have recently attracted interest in the USA, UK, and Europe as means to increase employability and support lifelong learning. This article aims to critically examine these objectives in order to guide the future e-portfolio practice. Design/methodology/approach: Social…

A Framework to Support S&T Planning for Royal Australian Navy Capability Acquisition

DTIC Science & Technology

2012-03-01

for guiding policy and assisting with strategic planning innovation processes. At the commencement of a Foresight Planning exercise the...for many Australian Defence Force (ADF) capability projects . Specifically, the methodology could prove beneficial in the development of science and...27 6.4 Selecting Appropriate Foresight Planning Methods ....................................... 28 7. SCIENCE AND

Design-Based School Improvement: A Practical Guide for Education Leaders

ERIC Educational Resources Information Center

Mintrop, Rick

2016-01-01

At the heart of the effort to enact and scale up successful school reforms is the need for more robust links between research and practice. One promising approach is design development, a methodology widely used in other fields and only recently adapted to education, which offers a disciplined process for identifying practical problems, assessing…

The Influence of Student Teacher Self-Regulation of Learning on Their Curricular Content-Knowledge and Course-Design Skills

ERIC Educational Resources Information Center

Shawer, Saad

2010-01-01

This investigation examined the influence of EFL student teacher self-regulation of learning (SRL) on their curricular content-knowledge and course-design skills. Positivism guided this study at the levels of: ontology (one form of reality); epistemology (detachment from the subjects); and methodology, using nomothetic research strategy (causal…

Understanding Fluorescence Measurements through a Guided-Inquiry and Discovery Experiment in Advanced Analytical Laboratory

ERIC Educational Resources Information Center

Wilczek-Vera, Grazyna; Salin, Eric Dunbar

2011-01-01

An experiment on fluorescence spectroscopy suitable for an advanced analytical laboratory is presented. Its conceptual development used a combination of the expository and discovery styles. The "learn-as-you-go" and direct "hands-on" methodology applied ensures an active role for a student in the process of visualization and discovery of concepts.…

Effective Online Lectures: Improving Practice through Design and Pedagogy

ERIC Educational Resources Information Center

Bese, Terry Lane

2016-01-01

The purpose of this research project was to improve the practice of using online lectures at a small private university. Using action research methodology, the researcher worked with a group of five university instructors to refine the use of online lectures through design and pedagogical practice. Beginning with a template or guide based on the…

Cognitive Task Analysis for Instruction in Single-Injection Ultrasound Guided-Regional Anesthesia

ERIC Educational Resources Information Center

Gucev, Gligor V.

2012-01-01

Cognitive task analysis (CTA) is methodology for eliciting knowledge from subject matter experts. CTA has been used to capture the cognitive processes, decision-making, and judgments that underlie expert behaviors. A review of the literature revealed that CTA has not yet been used to capture the knowledge required to perform ultrasound guided…

A Guided Inquiry Methodology to Achieve Authentic Science in a Large Undergraduate Biology Course

ERIC Educational Resources Information Center

Martineau, Carolyn; Traphagen, Stephen; Sparkes, Timothy C.

2013-01-01

University instructors are challenged to involve large student populations with varying pre-existing knowledge in authentic inquiry. We present a model in which students collaborate to design and run their own experiment and engage in peer evaluation. In the model, students in different lab sections of a multi-section course explore alternative…

On-Line Role-Play as a Teaching Method in Engineering Studies

ERIC Educational Resources Information Center

Cobo, Adolfo; Conde, Olga Ma.; Quintela, Ma. Ángeles; Mirapéix, Jesús Ma.; López-Higuera, José Miguel

2011-01-01

In this paper we propose adapting role-play teaching methodology to engineering studies. The role of a maintenance technician, a relevant job profile for engineering graduates is has chosen. The interaction is based on email exchange, with the instructor included in the simulation to help guide the activity and achieve learning objectives. In this…

Katie Gaebel at the Intersections of Resistance: Turkish Immigrant Women in German Schools

ERIC Educational Resources Information Center

Gaebel, Katie

2013-01-01

This paper focuses on two main guiding questions: first, what are the experiences of Turkish women in the German educational system; second, to what extent do state policies, cultural pressure, and personal choice influence the decision to pursue higher education? Using intersectionality as a methodology, this paper elucidates how women navigate…

Short Serious Games Creation under the Paradigm of Software Process and Competencies as Software Requirements. Case Study: Elementary Math Competencies

ERIC Educational Resources Information Center

Barajas-Saavedra, Arturo; Álvarez-Rodriguez, Francisco J.; Mendoza-González, Ricardo; Oviedo-De-Luna, Ana C.

2015-01-01

Development of digital resources is difficult due to their particular complexity relying on pedagogical aspects. Another aspect is the lack of well-defined development processes, experiences documented, and standard methodologies to guide and organize game development. Added to this, there is no documented technique to ensure correct…

How Elementary Teachers Use Classroom Mini-Economies When Guided by the C3 Framework

ERIC Educational Resources Information Center

Day, Stephen Harlan

2015-01-01

A mini-economy is an ongoing classroom project in which elementary school students apply for jobs, receive simulated income, go shopping at the classroom store, and ultimately create their own businesses. This study uses design-based research methodology to find out what classroom practices emerge when the College, Career, and Civic Life Framework…

WAVE DELAYING STRUCTURE FOR RECTANGULAR WAVE-GUIDES

DOEpatents

Robertson-Shersby-Harvie, R.B.; Dain, J.

1956-11-13

This patent relates to wave-guides and in particular describes wave delaying structure located within a wave-guide. The disclosed wave-guide has an elongated fiat metal sheet arranged in a central plane of the guide and formed with a series of transverse inductive slots such that each face presents an inductive impedance to the guide. The sheet is thickened in the area between slots to increase the self capacity of the slots. Experimental results indicate that in a wave-guide loaded in accordance with the invention the guided wavelength changes more slowly as the air wavelength is changed than the guided wavelength does in wave-guides loaded by means of corrugations.

Edgewood Independent School District Instructional Television Guides - Countdown, Teacher's Guide 5; Safari, Teacher's Guide 5; Probe, Teacher's Guide 6; Abacus, Teacher's Guide 6; Mathletics, Teacher's Guide 7; Algebraically Speaking, Teacher's Guide 8; Related Math I & II, Teacher's Guides 9 & 10; Spectra, Teacher's Guide 9.

ERIC Educational Resources Information Center

Bolton, Earle; Gueringer, June

Enclosed is a number of booklets containing lesson outlines of materials in mathematics and science. These outlines are designed to give teachers and students an idea of what to expect when a telecast is schedules for their classes. The tele-lessons are given for the purpose of providing enrichment activities and giving coherence to the entire…

[Summary of the consensus document: "Clinical practice guide for the management of low cardiac output syndrome in the postoperative period of heart surgery"].

PubMed

Pérez Vela, J L; Martín Benitez, J C; Carrasco Gonzalez, M; de la Cal López, M A; Hinojosa Pérez, R; Sagredo Meneses, V; del Nogal Saez, F

2012-05-01

Low cardiac output syndrome is a potential complication in cardiac surgery patients and is associated with increased morbidity and mortality. This guide provides recommendations for the management of these patients, immediately after surgery and following admission to the ICU. The recommendations are grouped into different sections, addressing from the most basic concepts such as definition of the disorder to the different sections of basic and advanced monitoring, and culminating with the complex management of this syndrome. We propose an algorithm for initial management, as well as two others for ventricular failure (predominantly left or right). Most of the recommendations are based on expert consensus, due to the lack of randomized trials of adequate design and sample size in patients of this kind. The quality of evidence and strength of the recommendations were based on the GRADE methodology. The guide is presented as a list of recommendations (with the level of evidence for each recommendation) for each question on the selected topic. For each question, justification of the recommendations is then provided. Copyright © 2011 Elsevier España, S.L. y SEMICYUC. All rights reserved.

[Clinical practice guide for the management of low cardiac output syndrome in the postoperative period of heart surgery].

PubMed

Pérez Vela, J L; Martín Benítez, J C; Carrasco González, M; de la Cal López, M A; Hinojosa Pérez, R; Sagredo Meneses, V; del Nogal Saez, F

2012-05-01

The low cardiac output syndrome is a potential complication in cardiac surgery patients and associated with increased morbidity and mortality. This guide is to provide recommendations for the management of these patients, immediately after surgery, admitted to the ICU. The recommendations are grouped into different sections, trying to answer from the most basic concepts such as the definition to the different sections of basic and advanced monitoring and ending with the complex management of this syndrome. We propose an algorithm for initial management, as well as two other for ventricular failure (predominantly left or right). Most of the recommendations are based on expert consensus because of the lack of randomized trials of adequate design and sample size in this group of patients. The quality of evidence and strength of the recommendations were made following the GRADE methodology. The guide is presented as a list of recommendations (and level of evidence for each recommendation) for each question on the selected topic. Then for each question, we proceed to the justification of the recommendations. Copyright © 2011 Elsevier España, S.L. y SEMICYUC. All rights reserved.

PCA Based Stress Monitoring of Cylindrical Specimens Using PZTs and Guided Waves

PubMed Central

Mujica, Luis; Ruiz, Magda; Camacho, Johanatan

2017-01-01

Since mechanical stress in structures affects issues such as strength, expected operational life and dimensional stability, a continuous stress monitoring scheme is necessary for a complete integrity assessment. Consequently, this paper proposes a stress monitoring scheme for cylindrical specimens, which are widely used in structures such as pipelines, wind turbines or bridges. The approach consists of tracking guided wave variations due to load changes, by comparing wave statistical patterns via Principal Component Analysis (PCA). Each load scenario is projected to the PCA space by means of a baseline model and represented using the Q-statistical indices. Experimental validation of the proposed methodology is conducted on two specimens: (i) a 12.7 mm (1/2″) diameter, 0.4 m length, AISI 1020 steel rod, and (ii) a 25.4 mm (1″) diameter, 6m length, schedule 40, A-106, hollow cylinder. Specimen 1 was subjected to axial loads, meanwhile specimen 2 to flexion. In both cases, simultaneous longitudinal and flexural guided waves were generated via piezoelectric devices (PZTs) in a pitch-catch configuration. Experimental results show the feasibility of the approach and its potential use as in-situ continuous stress monitoring application. PMID:29194384

The promise and challenge of practice-research collaborations: Guiding principles and strategies for initiating, designing, and implementing program evaluation research.

PubMed

Secret, Mary; Abell, Melissa L; Berlin, Trey

2011-01-01

The authors present a set of guiding principles and strategies to facilitate the collaborative efforts of social work researchers and practitioners as they initiate, design, and implement outcome evaluations of human service interventions and programs. Beginning with an exploration of the interpersonal barriers to practice-research collaborations, and building on their experiences in successfully completing a community-based research evaluation, the authors identify specific relationship-focused principles and strategies and illustrate how these approaches can guide practice-research teams through the various sequential activities of the evaluation research process. In particular, it is suggested that practice-research collaborations can be formed, strengthened, and sustained by emphasis on a spirit of discovery and shared leadership at the start of the relationship, use of a comprehensive evaluation model to clarify and frame the evaluation and program goals, beginning where the client is when selecting research methodology and measurement tools, commitment to keeping the program first and recording everything during the implementation and data-collection stages, discussion of emerging findings and presentation of findings in graphic format at the data-analysis stage, and a total team approach at the dissemination stage.

WAVE DELAYING STRUCTURE FOR RECTANGULAR WAVE-GUIDES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robertson-Shersby-Harvie, R.B.; Dain, J.

1956-11-13

This patent relates to wave-guides and in particular describes wave delaying structure located within a wave-guide. The disclosed wave-guide has an elongated fiat metal sheet arranged in a central plane of the guide and formed with a series of transverse inductive slots such that each face presents an inductive impedance to the guide. The sheet is thickened in the area between slots to increase the self capacity of the slots. Experimental results indicate that in a wave-guide loaded in accordance with the invention the guided wavelength changes more slowly as the air wavelength is changed than the guided wavelength doesmore » in wave-guides loaded by means of corrugations.« less

Model-driven Service Engineering with SoaML

NASA Astrophysics Data System (ADS)

Elvesæter, Brian; Carrez, Cyril; Mohagheghi, Parastoo; Berre, Arne-Jørgen; Johnsen, Svein G.; Solberg, Arnor

This chapter presents a model-driven service engineering (MDSE) methodology that uses OMG MDA specifications such as BMM, BPMN and SoaML to identify and specify services within a service-oriented architecture. The methodology takes advantage of business modelling practices and provides a guide to service modelling with SoaML. The presentation is case-driven and illuminated using the telecommunication example. The chapter focuses in particular on the use of the SoaML modelling language as a means for expressing service specifications that are aligned with business models and can be realized in different platform technologies.

Case based reasoning in criminal intelligence using forensic case data.

PubMed

Ribaux, O; Margot, P

2003-01-01

A model that is based on the knowledge of experienced investigators in the analysis of serial crime is suggested to bridge a gap between technology and methodology. Its purpose is to provide a solid methodology for the analysis of serial crimes that supports decision making in the deployment of resources, either by guiding proactive policing operations or helping the investigative process. Formalisation has helped to derive a computerised system that efficiently supports the reasoning processes in the analysis of serial crime. This novel approach fully integrates forensic science data.

A 6-Fr Guiding Catheter (Slim Guide®) for Use with Multiple Microdevices

PubMed Central

Kai, Y.; Ohmori, Y.; Watanabe, M.; Kaku, Y.; Morioka, M.; Hirano, T.; Yano, S.; Kawano, T.; Hamada, J-I.; Kuratsu, J-I.

2013-01-01

Summary A modified technique is required in patients with wide-necked aneurysms whose treatment by the single microcatheter technique is difficult. We developed a 6-Fr guiding catheter (Slim Guide®) that features a large lumen (0.072 inch) for performing the modified technique. To evaluate the usefulness of Slim Guide® we carried out experiments using three types of 6-Fr guiding catheter. In experiment 1, the shaft hardness and kink resistance were compared among three different guiding catheters (Slim Guide®, Launcher®, Envoy®). In experiment 2, we inserted a microballoon catheter and a microcatheter into the three different guiding catheters and recorded the maximal infusion pressure. In experiment 3, we inserted 13 different types of microdevices into the three different guiding catheters and evaluated the resistance of the microdevices. Although the shaft of the Slim Guide® was softer than that of the other two guiding catheters, its kink resistance was comparable. The maximal infusion pressure was significantly lower than with Launcher® or Envoy® catheters. Furthermore, with Slim Guide®, in 136 of 143 microdevice combinations examined (95.1%) there was no resistance; this was true for 125 (87.4%) and 116 (81.1%) combinations using the Launcher® - and the Envoy® guiding catheters, respectively. There was a significant difference between Slim Guide® and the other two guiding catheters with respect to their accommodation of double microsystems (p<0.05). Although the inner diameter of Slim Guide® is slightly larger than of the other two guiding catheters, it significantly increased the combination of microdevices that could be used for the coil embolization of difficult aneurysms. PMID:23472717

A 6-fr guiding catheter (slim guide(®)) for use with multiple microdevices. An experimental study.

PubMed

Kai, Y; Ohmori, Y; Watanabe, M; Kaku, Y; Morioka, M; Hirano, T; Yano, S; Kawano, T; Hamada, J-I; Kuratsu, J-I

2013-03-01

A modified technique is required in patients with wide-necked aneurysms whose treatment by the single microcatheter technique is difficult. We developed a 6-Fr guiding catheter (Slim Guide(®)) that features a large lumen (0.072 inch) for performing the modified technique. To evaluate the usefulness of Slim Guide(®) we carried out experiments using three types of 6-Fr guiding catheter. In experiment 1, the shaft hardness and kink resistance were compared among three different guiding catheters (Slim Guide(®), Launcher(®), Envoy(®)). In experiment 2, we inserted a microballoon catheter and a microcatheter into the three different guiding catheters and recorded the maximal infusion pressure. In experiment 3, we inserted 13 different types of microdevices into the three different guiding catheters and evaluated the resistance of the microdevices. Although the shaft of the Slim Guide(®) was softer than that of the other two guiding catheters, its kink resistance was comparable. The maximal infusion pressure was significantly lower than with Launcher(®) or Envoy(®) catheters. Furthermore, with Slim Guide(®), in 136 of 143 microdevice combinations examined (95.1%) there was no resistance; this was true for 125 (87.4%) and 116 (81.1%) combinations using the Launcher(®) - and the Envoy(®) guiding catheters, respectively. There was a significant difference between Slim Guide(®) and the other two guiding catheters with respect to their accommodation of double microsystems (p<0.05). Although the inner diameter of Slim Guide(®) is slightly larger than of the other two guiding catheters, it significantly increased the combination of microdevices that could be used for the coil embolization of difficult aneurysms.

Wild bees preferentially visit Rudbeckia flower heads with exaggerated ultraviolet absorbing floral guides

PubMed Central

Horth, Lisa; Campbell, Laura; Bray, Rebecca

2014-01-01

ABSTRACT Here, we report on the results of an experimental study that assessed the visitation frequency of wild bees to conspecific flowers with different sized floral guides. UV absorbent floral guides are ubiquitous in Angiosperms, yet surprisingly little is known about conspecific variation in these guides and very few studies have evaluated pollinator response to UV guide manipulation. This is true despite our rich understanding about learning and color preferences in bees. Historical dogma indicates that flower color serves as an important long-range visual signal allowing pollinators to detect the flowers, while floral guides function as close-range signals that direct pollinators to a reward. We initiated the work presented here by first assessing the population level variation in UV absorbent floral guides for conspecific flowers. We assessed two species, Rudbeckia hirta and R. fulgida. We then used several petal cut-and-paste experiments to test whether UV floral guides can also function to attract visitors. We manipulated floral guide size and evaluated visitation frequency. In all experiments, pollinator visitation rates were clearly associated with floral guide size. Diminished floral guides recruited relatively few insect visitors. Exaggerated floral guides recruited more visitors than smaller or average sized guides. Thus, UV floral guides play an important role in pollinator recruitment and in determining the relative attractiveness of conspecific flower heads. Consideration of floral guides is therefore important when evaluating the overall conspicuousness of flower heads relative to background coloration. This work raises the issue of whether floral guides serve as honest indicators of reward, since guide size varies in nature for conspecific flowers at the same developmental stage and since preferences for larger guides were found. To our knowledge, these are the first cut-and-paste experiments conducted to examine whether UV absorbent floral guides affect visitation rates and pollinator preference. PMID:24585774

Wild bees preferentially visit Rudbeckia flower heads with exaggerated ultraviolet absorbing floral guides.

PubMed

Horth, Lisa; Campbell, Laura; Bray, Rebecca

2014-03-15

Here, we report on the results of an experimental study that assessed the visitation frequency of wild bees to conspecific flowers with different sized floral guides. UV absorbent floral guides are ubiquitous in Angiosperms, yet surprisingly little is known about conspecific variation in these guides and very few studies have evaluated pollinator response to UV guide manipulation. This is true despite our rich understanding about learning and color preferences in bees. Historical dogma indicates that flower color serves as an important long-range visual signal allowing pollinators to detect the flowers, while floral guides function as close-range signals that direct pollinators to a reward. We initiated the work presented here by first assessing the population level variation in UV absorbent floral guides for conspecific flowers. We assessed two species, Rudbeckia hirta and R. fulgida. We then used several petal cut-and-paste experiments to test whether UV floral guides can also function to attract visitors. We manipulated floral guide size and evaluated visitation frequency. In all experiments, pollinator visitation rates were clearly associated with floral guide size. Diminished floral guides recruited relatively few insect visitors. Exaggerated floral guides recruited more visitors than smaller or average sized guides. Thus, UV floral guides play an important role in pollinator recruitment and in determining the relative attractiveness of conspecific flower heads. Consideration of floral guides is therefore important when evaluating the overall conspicuousness of flower heads relative to background coloration. This work raises the issue of whether floral guides serve as honest indicators of reward, since guide size varies in nature for conspecific flowers at the same developmental stage and since preferences for larger guides were found. To our knowledge, these are the first cut-and-paste experiments conducted to examine whether UV absorbent floral guides affect visitation rates and pollinator preference.

Guided university debate: Effect of a new teaching-learning strategy for undergraduate nursing students.

PubMed

Arrue, Marta; Unanue, Saloa; Merida, David

2017-12-01

A number of studies have shown that the traditional lecture suffers from limitations in the development of many important competencies such as reasoning ability for nursing professionals. In view of this issue, the authors present a promising alternative to the traditional lecture: the Guided University Debate (GUD). With regard to this aim a teaching-learning sequence of schizophrenia is described based on the GUD. Next, the improvement in the argumentative and declarative knowledge of the students who have participated in the said methodology is demonstrated. Quasi-experimental study with pre-test and post-test design to measure differences in the improvement of declarative and argumentative knowledge. To determine if there is a statistically significant difference in the score obtained in the pre-test and in the post-test score a parametric t-tests was carried. 64 students participated in the study. Implementation of the study took place during the 2015-2016 academic year in the third year of the Nursing undergraduate degree course in the University of the Basque Country (UPV/EHU) as part of the Mental Health class. The results showed a statistically-significant improvement in the students' scores for all learning outcomes analysed: Identifies symptoms of schizophrenia (p≤0.001), identifies the nursing interventions (p≤0.001), provides a rationale for nursing interventions (p≤0.001) and provides evidence of nursing interventions (p≤0.001). That is, the declarative and argumentative capacity of the group improved significantly with the Guided University Debate methodology. Although the teaching design feasibility and outcomes may vary in different contexts, based on this studies' positive outcome, the authors call today's educators to be able to use GUD as a teaching method. Copyright © 2017 Elsevier Ltd. All rights reserved.

A Call to Digital Health Practitioners: New Guidelines Can Help Improve the Quality of Digital Health Evidence

PubMed Central

Agarwal, Smisha; Lefevre, Amnesty E

2017-01-01

Background Despite the rapid proliferation of health interventions that employ digital tools, the evidence on the effectiveness of such approaches remains insufficient and of variable quality. To address gaps in the comprehensiveness and quality of reporting on the effectiveness of digital programs, the mHealth Technical Evidence Review Group (mTERG), convened by the World Health Organization, proposed the mHealth Evidence Reporting and Assessment (mERA) checklist to address existing gaps in the comprehensiveness and quality of reporting on the effectiveness of digital health programs. Objective We present an overview of the mERA checklist and encourage researchers working in the digital health space to use the mERA checklist for reporting their research. Methods The development of the mERA checklist consisted of convening an expert group to recommend an appropriate approach, convening a global expert review panel for checklist development, and pilot-testing the checklist. Results The mERA checklist consists of 16 core mHealth items that define what the mHealth intervention is (content), where it is being implemented (context), and how it was implemented (technical features). Additionally, a 29-item methodology checklist guides authors on reporting critical aspects of the research methodology employed in the study. We recommend that the core mERA checklist is used in conjunction with an appropriate study-design specific checklist. Conclusions The mERA checklist aims to assist authors in reporting on digital health research, guide reviewers and policymakers in synthesizing evidence, and guide journal editors in assessing the completeness in reporting on digital health studies. An increase in transparent and rigorous reporting can help identify gaps in the conduct of research and understand the effects of digital health interventions as a field of inquiry. PMID:28986340

Cultural Competence in the Treatment of Addictions: Theory, Practice and Evidence.

PubMed

Gainsbury, Sally M

2017-07-01

Culturally and linguistically diverse (CALD) populations often have high rates of addictive disorders, but lower rates of treatment seeking and completion than the mainstream population. A significant barrier to treatment is the lack of culturally relevant and appropriate treatment. A literature review was conducted to identify relevant literature related to cultural competence in mental health services delivery and specifically treatment for addictive disorders. Several theoretical models of cultural competence in therapy have been developed, but the lack of rigorous research limits the empirical evidence available. Research indicates that culturally competent treatment practices including providing therapy and materials in the client's language, knowledge, understanding and appreciation for cultural perspectives and nuances, involving the wider family and community and training therapists can enhance client engagement, retention and treatment outcomes for substance use and gambling. Further methodologically rigorous research is needed to isolate the impact of cultural competence for the treatment of addictions and guide research to determine treatment efficacy within specific CALD populations. Training therapists and recruiting therapists and researchers from CALD communities is important to ensure an ongoing focus and improved outcomes for CALD populations due to the importance of engaging these populations with addiction treatment. Copyright © 2016 John Wiley & Sons, Ltd. Key Practitioner Message: The treatment needs of culturally diverse individuals with addictions are often not met. Theoretical models can guide therapists in incorporating cultural competence. Culturally targeted treatments increase recruitment, retention and treatment outcomes. Cultural competence includes matching clinicians and clients on linguistic and cultural backgrounds as well as being mindful of the impact of culture on client's experience of addiction problems. Few methodologically rigorous trials have been conducted to guide treatment practices and research needs to be incorporated into existing culturally relevant treatment services. Copyright © 2016 John Wiley & Sons, Ltd.

Getting a Job: Educators' Guides and Supporting Documents

ERIC Educational Resources Information Center

PEPNet 2, 2013

2013-01-01

This paper presents a collection of videos that provide ideas on getting jobs for educators. Contents include: (1) Educator's Guide: Introduction to the Video Series; (2) Educator's Guide: Your Journey; (3) Educator's Guide: Your Rights and Responsibilities; (4) Educator's Guide: Introduction to Vocational Rehabilitation; (5) Educator's Guide:…

Optical power splitter and polarization splitter

NASA Technical Reports Server (NTRS)

Bogert, Gail A. (Inventor)

1988-01-01

A 3.times.3 optical guiding arrangement is disclosed for providing both power splitting between a pair of output guides in the 3.times.3 guide structure and polarization splitting (into the TE and TM modes) between the central guide and the pair of outer guides. In accordance with the present invention, the mutual coupling length L and separation distance d between adjacent guides are chosen to provide the desired polarization splitting and total intensity (power) in the outer guides. For example, an input signal of intensity I comprising both the TE and TM modes may be launched in the center guide and with correct choices for L and d, will result in output signals of I.sub.TM /2 each of the outer pair of guides and I.sub.TE from the central guide.

Materials discovery guided by data-driven insights

NASA Astrophysics Data System (ADS)

Klintenberg, Mattias

As the computational power continues to grow systematic computational exploration has become an important tool for materials discovery. In this presentation the Electronic Structure Project (ESP/ELSA) will be discussed and a number of examples presented that show some of the capabilities of a data-driven methodology for guiding materials discovery. These examples include topological insulators, detector materials and 2D materials. ESP/ELSA is an initiative that dates back to 2001 and today contain many tens of thousands of materials that have been investigated using a robust and high accuracy electronic structure method (all-electron FP-LMTO) thus providing basic materials first-principles data for most inorganic compounds that have been structurally characterized. The web-site containing the ESP/ELSA data has as of today been accessed from more than 4,000 unique computers from all around the world.

Critical reading and critical thinking--study design and methodology: a personal approach on how to read the clinical literature.

PubMed

Lipman, Timothy O

2013-04-01

The volume of medical literature grows exponentially. Yet we are faced with the necessity to make clinical decisions based on the availability and quality of scientific information. The general strength (reliability, robustness) of any interpretation that guides us in clinical decision making is dependent on how information was obtained. All information and medical studies and, consequently, all conclusions are not created equal. It is incumbent upon us to be able to assess the quality of the information that guides us in the care of our patients. Being able to assess medical literature critically requires use of critical reading and critical thinking skills. To achieve these skills, to be able to analyze medical literature critically, takes a combination of education and practice, practice, and more practice.

Model-based guiding pattern synthesis for robust assembly of contact layers using directed self-assembly

NASA Astrophysics Data System (ADS)

Mitra, Joydeep; Torres, Andres; Ma, Yuansheng; Pan, David Z.

2018-01-01

Directed self-assembly (DSA) has emerged as one of the most compelling next-generation patterning techniques for sub 7 nm via or contact layers. A key issue in enabling DSA as a mainstream patterning technique is the generation of grapho-epitaxy-based guiding pattern (GP) shapes to assemble the contact patterns on target with high fidelity and resolution. Current GP generation is mostly empirical, and limited to a very small number of via configurations. We propose the first model-based GP synthesis algorithm and methodology for on-target and robust DSA, on general via pattern configurations. The final postoptical proximity correction-printed GPs derived from our original synthesized GPs are resilient to process variations and continue to maintain the same DSA fidelity in terms of placement error and target shape.

Predictive simulation of guide-wave structural health monitoring

NASA Astrophysics Data System (ADS)

Giurgiutiu, Victor

2017-04-01

This paper presents an overview of recent developments on predictive simulation of guided wave structural health monitoring (SHM) with piezoelectric wafer active sensor (PWAS) transducers. The predictive simulation methodology is based on the hybrid global local (HGL) concept which allows fast analytical simulation in the undamaged global field and finite element method (FEM) simulation in the local field around and including the damage. The paper reviews the main results obtained in this area by researchers of the Laboratory for Active Materials and Smart Structures (LAMSS) at the University of South Carolina, USA. After thematic introduction and research motivation, the paper covers four main topics: (i) presentation of the HGL analysis; (ii) analytical simulation in 1D and 2D; (iii) scatter field generation; (iv) HGL examples. The paper ends with summary, discussion, and suggestions for future work.

Magnetic Resonance-Guided High-Intensity Focused Ultrasound (MR-HIFU) in Treatment of Symptomatic Uterine Myomas

PubMed Central

Filipowska, Justyna; Łoziński, Tomasz

2014-01-01

Summary Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) is a noninvasive technique for ablation therapy for uterine myomas, where focused ultrasound energy beam generates localized high temperature in the selected area and coagulates chosen tissue, leaving the skin and tissues in between unharmed. Magnetic resonance imaging enables accurate targeting for HIFU as well as temperature monitoring during treatment. MR guidance with 3D anatomical imaging provides reference data for treatment planning, while real-time temperature monitoring aids in controlling ablation process. This review provides basic information regarding methodology, clinical indications for this kind of treatment, expected outcome and patient management during MR-HIFU procedure. The aim of this work is to introduce a new, noninvasive treatment method for uterine leiomyomas and to present a comparison with other currently used methods. PMID:25469176

Magnetic Resonance-Guided High-Intensity Focused Ultrasound (MR-HIFU) in Treatment of Symptomatic Uterine Myomas.

PubMed

Filipowska, Justyna; Loziński, Tomasz

2014-01-01

Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) is a noninvasive technique for ablation therapy for uterine myomas, where focused ultrasound energy beam generates localized high temperature in the selected area and coagulates chosen tissue, leaving the skin and tissues in between unharmed. Magnetic resonance imaging enables accurate targeting for HIFU as well as temperature monitoring during treatment. MR guidance with 3D anatomical imaging provides reference data for treatment planning, while real-time temperature monitoring aids in controlling ablation process. This review provides basic information regarding methodology, clinical indications for this kind of treatment, expected outcome and patient management during MR-HIFU procedure. The aim of this work is to introduce a new, noninvasive treatment method for uterine leiomyomas and to present a comparison with other currently used methods.

Multiple Concentric Cylinder Model (MCCM) user's guide

NASA Technical Reports Server (NTRS)

Williams, Todd O.; Pindera, Marek-Jerzy

1994-01-01

A user's guide for the computer program mccm.f is presented. The program is based on a recently developed solution methodology for the inelastic response of an arbitrarily layered, concentric cylinder assemblage under thermomechanical loading which is used to model the axisymmetric behavior of unidirectional metal matrix composites in the presence of various microstructural details. These details include the layered morphology of certain types of ceramic fibers, as well as multiple fiber/matrix interfacial layers recently proposed as a means of reducing fabrication-induced, and in-service, residual stress. The computer code allows efficient characterization and evaluation of new fibers and/or new coating systems on existing fibers with a minimum of effort, taking into account inelastic and temperature-dependent properties and different morphologies of the fiber and the interfacial region. It also facilitates efficient design of engineered interfaces for unidirectional metal matrix composites.

Masters Thesis- Criticality Alarm System Design Guide with Accompanying Alarm System Development for the Radioisotope Production Laboratory in Richland, Washington

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greenfield, Bryce A.

2009-12-01

A detailed instructional manual was created to guide criticality safety engineers through the process of designing a criticality alarm system (CAS) for Department of Energy (DOE) hazard class 1 and 2 facilities. Regulatory and technical requirements were both addressed. A list of design tasks and technical subtasks are thoroughly analyzed to provide concise direction for how to complete the analysis. An example of the application of the design methodology, the Criticality Alarm System developed for the Radioisotope Production Laboratory (RPL) of Richland, Washington is also included. The analysis for RPL utilizes the Monte Carlo code MCNP5 for establishing detector coveragemore » in the facility. Significant improvements to the existing CAS were made that increase the reliability, transparency, and coverage of the system.« less

International year of Chemistry 2011. A guide to the history of clinical chemistry.

PubMed

Kricka, Larry J; Savory, John

2011-08-01

This review was written as part of the celebration of the International Year of Chemistry 2011. In this review we provide a chronicle of the history of clinical chemistry, with a focus on North America. We outline major methodological advances and trace the development of professional societies and journals dedicated to clinical chemistry. This review also serves as a guide to reference materials for those interested in the history of clinical chemistry. The various resources available, in sound recordings, videos, moving images, image and document archives, museums, and websites dedicated to diagnostic company timelines, are surveyed. These resources provide a map of how the medical subspecialty of clinical chemistry arrived at its present state. This information will undoubtedly help visionaries to determine in which direction clinical chemistry will move in the future.

Cell-block procedure in endoscopic ultrasound-guided-fine-needle-aspiration of gastrointestinal solid neoplastic lesions

PubMed Central

Ieni, Antonio; Barresi, Valeria; Todaro, Paolo; Caruso, Rosario Alberto; Tuccari, Giovanni

2015-01-01

In the present review we have analyzed the clinical applications of endoscopic ultrasound-guided-fine-needle-aspiration (EUS-FNA) and the methodological aspects obtained by cell-block procedure (CBP) in the diagnostic approach to the gastrointestinal neoplastic pathology. CBP showed numerous advantages in comparison to the cytologic routine smears; in particular, better preservation of cell architecture, achievement of routine haematoxylin-eosin staining equivalent to histological slides and possibility to perform immunohistochemistry or molecular analyses represented the most evident reasons to choose this method. Moreover, by this approach, the differential diagnosis of solid gastrointestinal neoplasias may be more easily achieved and the background of contaminant non-neoplastic gastrointestinal avoided. Finally, biological samples collected by EUS-FNA CBP-assisted should be investigated in order to identify and quantify further potential molecular markers. PMID:26322154

Evaluation of automated decisionmaking methodologies and development of an integrated robotic system simulation. Appendix A: ROBSIM user's guide

NASA Technical Reports Server (NTRS)

Haley, D. C.; Almand, B. J.; Thomas, M. M.; Krauze, L. D.; Gremban, K. D.; Sanborn, J. C.; Kelley, J. H.; Depkovich, T. M.; Wolfe, W. J.; Nguyen, T.

1986-01-01

The purpose of the Robotics Simulation Program is to provide a broad range of computer capabilities to assist in the design, verification, simulation, and study of robotics systems. ROBSIM is program in FORTRAN 77 for use on a VAX 11/750 computer under the VMS operating system. This user's guide describes the capabilities of the ROBSIM programs, including the system definition function, the analysis tools function and the postprocessor function. The options a user may encounter with each of these executables are explained in detail and the different program prompts appearing to the user are included. Some useful suggestions concerning the appropriate answers to be given by the user are provided. An example user interactive run in enclosed for each of the main program services, and some of the capabilities are illustrated.

[Adolescense pregnancy in a marginalized rural community in Mexico].

PubMed

Jiménez-González, Alberto; Granados-Cosme, José Arturo; Rosales-Flores, Roselia Arminda

2017-01-01

To identify objective and subjective conditions in the lives of pregnant teens within a highly-marginalized community in the state of Puebla, Mexico. Objective and subjective conditions of pregnant teens were evaluated through a mixed methodology (surveys, observation guides and a structured interview guide). The main family characteristic is the absence of a father due to migration, no desire to study or work and the new meaning of pregnancy: the initial social stigma for engaging in a sexual activity and then, the stigma for being a young mother. Objective conditions show family disintegration, lack of access to education at the community, high school and college level as well as unemployment as processes linked to teen pregnancy; thus, making it practically impossible to develop life goals. Subjective conditions center around the reproduction of gender stereotypes related to maternity.

Reading Guided by Automated Graphical Representations: How Model-Based Text Visualizations Facilitate Learning in Reading Comprehension Tasks

ERIC Educational Resources Information Center

Pirnay-Dummer, Pablo; Ifenthaler, Dirk

2011-01-01

Our study integrates automated natural language-oriented assessment and analysis methodologies into feasible reading comprehension tasks. With the newly developed T-MITOCAR toolset, prose text can be automatically converted into an association net which has similarities to a concept map. The "text to graph" feature of the software is based on…

Meeting the Challenge of Interpretation: Hearing the Voices of People with Intellectual and Developmental Disability through I-Poems

ERIC Educational Resources Information Center

Corby, Deirdre; Taggart, Laurence; Cousins, Wendy

2018-01-01

Including the inner perspectives of people who have intellectual disability can pose methodological challenges to qualitative researchers. This article explains how the Listening Guide was applied as an additional step in the analysis during a study which used hermeneutic interviews with people with intellectual disability as the sole method of…

Building Bridges in a Third Space: A Phenomenological Study of the Lived Experiences of Teaching Chinese in American Chinese Schools

ERIC Educational Resources Information Center

Weng, Xuan; Lin, Jing

2013-01-01

This study explores the lived experiences of Chinese teachers in American Chinese Schools. Max van Manen's methodology for hermeneutic phenomenological research provides a framework for the study, and the philosophical writings of Heidegger, Gadamer, and Derrida guide the textual interpretations. Pedagogical voices of Aoki, Pinar, and Greene,…

Integrated Systems Oriented Student-Centric Learning Environment: A Framework for Curriculum Development

ERIC Educational Resources Information Center

Mayur, S. Desai

2013-01-01

Purpose: The purpose of this paper is to propose a framework that serves as a guide to develop a curriculum and instructional strategy that is systems oriented and student-centric. Design/methodology/approach: The framework is based on the theories in the field of education by prominent researchers. The framework is divided into four sub-systems,…

Methodology and User Guide for the Food Intakes Converted to Retail Commodities Databases: CSFII 1994-1996 and 1998; NHANES 1999-2000; WWEIA, NHANES 2001-2002

USDA-ARS?s Scientific Manuscript database

The purpose for developing the Food Intakes Converted to Retail Commodities Database (FICRCD) is to convert foods consumed in the national dietary surveys, 1994-2002, to respective amounts of retail-level food commodities. Food commodities are defined as those available for purchase in retail store...

Predictive and mechanistic multivariate linear regression models for reaction development

PubMed Central

Santiago, Celine B.; Guo, Jing-Yao

2018-01-01

Multivariate Linear Regression (MLR) models utilizing computationally-derived and empirically-derived physical organic molecular descriptors are described in this review. Several reports demonstrating the effectiveness of this methodological approach towards reaction optimization and mechanistic interrogation are discussed. A detailed protocol to access quantitative and predictive MLR models is provided as a guide for model development and parameter analysis. PMID:29719711

MEMS Reliability Assurance Guidelines for Space Applications

NASA Technical Reports Server (NTRS)

Stark, Brian (Editor)

1999-01-01

This guide is a reference for understanding the various aspects of microelectromechanical systems, or MEMS, with an emphasis on device reliability. Material properties, failure mechanisms, processing techniques, device structures, and packaging techniques common to MEMS are addressed in detail. Design and qualification methodologies provide the reader with the means to develop suitable qualification plans for the insertion of MEMS into the space environment.

A Guide for Setting the Cut-Scores to Minimize Weighted Classification Errors in Test Batteries

ERIC Educational Resources Information Center

Grabovsky, Irina; Wainer, Howard

2017-01-01

In this article, we extend the methodology of the Cut-Score Operating Function that we introduced previously and apply it to a testing scenario with multiple independent components and different testing policies. We derive analytically the overall classification error rate for a test battery under the policy when several retakes are allowed for…

K Basin Hazard Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

PECH, S.H.

This report describes the methodology used in conducting the K Basins Hazard Analysis, which provides the foundation for the K Basins Final Safety Analysis Report. This hazard analysis was performed in accordance with guidance provided by DOE-STD-3009-94, Preparation Guide for U. S. Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports and implements the requirements of DOE Order 5480.23, Nuclear Safety Analysis Report.

Traditional vs. Simulated Guided Methodology in Teaching Vital Sign Assessment of the Normal Newborn to the Nursing Student: A Clinical Outcome Evaluation

ERIC Educational Resources Information Center

Rivers, Joynelle L.

2012-01-01

Nursing education faces many challenges such as faculty shortages, inadequate clinical site placements, the inability to accept qualified students because of limited resources, and how to effectively educate students who are tech savvy, confident, highly motivated yet have differing needs from previous generations. This study sought to explore how…

Context Matters: The Value of Analyzing Human Factors within Educational Contexts as a Way of Informing Technology-Related Decisions within Design Research

ERIC Educational Resources Information Center

MacKinnon, Kim

2012-01-01

While design research can be useful for designing effective technology integrations within complex social settings, it currently fails to provide concrete methodological guidelines for gathering and organizing information about the research context, or for determining how such analyses ought to guide the iterative design and innovation process. A…

Bases para el Curriculum del Primer Ciclo de las Escuelas de Nivel Intermedio (Bases for the First Term Curriculum in Intermediate Schools).

ERIC Educational Resources Information Center

Fermin Mignone, Emilio; And Others

This curriculum guide for intermediate schools in Argentina begins with a discussion of the historical development of such schools and of their place in the overall educational scheme. The section on the curriculum provides detailed information on objectives, content, and activities; philosophical, political, sociological, methodological, and…

The GRASP 3: Graphical Reliability Analysis Simulation Program. Version 3: A users' manual and modelling guide

NASA Technical Reports Server (NTRS)

Phillips, D. T.; Manseur, B.; Foster, J. W.

1982-01-01

Alternate definitions of system failure create complex analysis for which analytic solutions are available only for simple, special cases. The GRASP methodology is a computer simulation approach for solving all classes of problems in which both failure and repair events are modeled according to the probability laws of the individual components of the system.

The Discursive Construction of Identity: An Analysis of Positioning in the Conversational Narratives of Japanese Preservice Teachers of English

ERIC Educational Resources Information Center

Rugen, Brian David

2009-01-01

Contemporary research suggests that forming a professional identity is crucial to the process of becoming a teacher. Furthermore, a "narrative turn" has emerged as a major methodological influence for the study of identity in research on teaching. A guiding assumption of traditional narrative research is that stories act as…

State, Adoption and Use of ICTs by Students and Academic Staff at Mzuzu University, Malawi

ERIC Educational Resources Information Center

Chaputula, Aubrey Harvey

2012-01-01

Purpose: The purpose of this research is to look at the state, adoption and use of ICTs by students and academic staff at Mzuzu University. Design/methodology/approach: The research used a survey method whose study population included students, academic and library staff. Data for the study were collected using an interview guide and…

Experimental Designs in Sentence Processing Research: A Methodological Review and User's Guide

ERIC Educational Resources Information Center

Keating, Gregory D.; Jegerski, Jill

2015-01-01

Since the publication of Clahsen and Felser's (2006) keynote article on grammatical processing in language learners, the online study of sentence comprehension in adult second language (L2) learners has quickly grown into a vibrant and prolific subfield of SLA. As online methods begin to establish a foothold in SLA research, it is important…

A Comparison of Functional Behavior Assessment Methodologies with Young Children: Descriptive Methods and Functional Analysis

ERIC Educational Resources Information Center

Alter, Peter J.; Conroy, Maureen A.; Mancil, G. Rich; Haydon, Todd

2008-01-01

The use of functional behavior assessment (FBA) to guide the development of behavior intervention plans continues to increase since they were first mandated in IDEA (Individuals with Disabilities Education Act Amendments of 1997, 20 U.S.C. Section 1400 et seq, 1997). A variety of indirect and direct instruments have been developed to facilitate…

Characterizing Measurement Error in Test Scores across Studies: A Tutorial on Conducting "Reliability Generalization" Analyses.

ERIC Educational Resources Information Center

Henson, Robin K.; Thompson, Bruce

Given the potential value of reliability generalization (RG) studies in the development of cumulative psychometric knowledge, the purpose of this paper is to provide a tutorial on how to conduct such studies and to serve as a guide for researchers wishing to use this methodology. After some brief comments on classical test theory, the paper…

Using an Android application to assess registration strategies in open hepatic procedures: a planning and simulation tool

NASA Astrophysics Data System (ADS)

Doss, Derek J.; Heiselman, Jon S.; Collins, Jarrod A.; Weis, Jared A.; Clements, Logan W.; Geevarghese, Sunil K.; Miga, Michael I.

2017-03-01

Sparse surface digitization with an optically tracked stylus for use in an organ surface-based image-to-physical registration is an established approach for image-guided open liver surgery procedures. However, variability in sparse data collections during open hepatic procedures can produce disparity in registration alignments. In part, this variability arises from inconsistencies with the patterns and fidelity of collected intraoperative data. The liver lacks distinct landmarks and experiences considerable soft tissue deformation. Furthermore, data coverage of the organ is often incomplete or unevenly distributed. While more robust feature-based registration methodologies have been developed for image-guided liver surgery, it is still unclear how variation in sparse intraoperative data affects registration. In this work, we have developed an application to allow surgeons to study the performance of surface digitization patterns on registration. Given the intrinsic nature of soft-tissue, we incorporate realistic organ deformation when assessing fidelity of a rigid registration methodology. We report the construction of our application and preliminary registration results using four participants. Our preliminary results indicate that registration quality improves as users acquire more experience selecting patterns of sparse intraoperative surface data.

Best Practices in the Evaluation of Large-scale STEM-focused Events: A Review of Recent Literature

NASA Astrophysics Data System (ADS)

Shebby, S.; Cobb, W. H.; Buxner, S.; Shipp, S. S.

2015-12-01

Each year, the National Aeronautics and Space Administration (NASA) sponsors a variety of educational events to share information with educators, students, and the general public. Intended outcomes of these events include increased interest in and awareness of the mission and goals of NASA. Events range in size from relatively small family science nights at a local school to large-scale mission and celestial event celebrations involving thousands of members of the general public. To support community members in designing event evaluations, the Science Mission Directorate (SMD) Planetary Science Forum sponsored the creation of a Best Practices Guide. The guide was generated by reviewing published large-scale event evaluation reports; however, the best practices described within are pertinent for all event organizers and evaluators regardless of event size. Each source included in the guide identified numerous challenges to conducting their event evaluation. These included difficulty in identifying extant instruments or items, collecting representative data, and disaggregating data to inform different evaluation questions. Overall, the guide demonstrates that evaluations of the large-scale events are generally done at a very basic level, with the types of data collected limited to observable demographic information and participant reactions collected via online survey. In addition to these findings, this presentation will describe evaluation best practices that will help practitioners move beyond these basic indicators and examine how to make the evaluation process an integral—and valuable—element of event planning, ultimately informing event outcomes and impacts. It will provide detailed information on five recommendations presented in the guide: 1) consider evaluation methodology, including data analysis, in advance; 2) design data collection instruments well in advance of the event; 3) collect data at different times and from multiple sources; 4) use technology to make the job easier; and 5) be aware of how challenging it is to measure impact.

Do guided internet-based interventions result in clinically relevant changes for patients with depression? An individual participant data meta-analysis.

PubMed

Karyotaki, Eirini; Ebert, David Daniel; Donkin, Liesje; Riper, Heleen; Twisk, Jos; Burger, Simone; Rozental, Alexander; Lange, Alfred; Williams, Alishia D; Zarski, Anna Carlotta; Geraedts, Anna; van Straten, Annemieke; Kleiboer, Annet; Meyer, Björn; Ünlü Ince, Burçin B; Buntrock, Claudia; Lehr, Dirk; Snoek, Frank J; Andrews, Gavin; Andersson, Gerhard; Choi, Isabella; Ruwaard, Jeroen; Klein, Jan Philipp; Newby, Jill M; Schröder, Johanna; Laferton, Johannes A C; Van Bastelaar, Kim; Imamura, Kotaro; Vernmark, Kristofer; Boß, Leif; Sheeber, Lisa B; Kivi, Marie; Berking, Matthias; Titov, Nickolai; Carlbring, Per; Johansson, Robert; Kenter, Robin; Perini, Sarah; Moritz, Steffen; Nobis, Stephanie; Berger, Thomas; Kaldo, Viktor; Forsell, Yvonne; Lindefors, Nils; Kraepelien, Martin; Björkelund, Cecilia; Kawakami, Norito; Cuijpers, Pim

2018-06-19

Little is known about clinically relevant changes in guided Internet-based interventions for depression. Moreover, methodological and power limitations preclude the identification of patients' groups that may benefit more from these interventions. This study aimed to investigate response rates, remission rates, and their moderators in randomized controlled trials (RCTs) comparing the effect of guided Internet-based interventions for adult depression to control groups using an individual patient data meta-analysis approach. Literature searches in PubMed, Embase, PsycINFO and Cochrane Library resulted in 13,384 abstracts from database inception to January 1, 2016. Twenty-four RCTs (4889 participants) comparing a guided Internet-based intervention with a control group contributed data to the analysis. Missing data were multiply imputed. To examine treatment outcome on response and remission, mixed-effects models with participants nested within studies were used. Response and remission rates were calculated using the Reliable Change Index. The intervention group obtained significantly higher response rates (OR = 2.49, 95% CI 2.17-2.85) and remission rates compared to controls (OR = 2.41, 95% CI 2.07-2.79). The moderator analysis indicated that older participants (OR = 1.01) and native-born participants (1.66) were more likely to respond to treatment compared to younger participants and ethnic minorities respectively. Age (OR = 1.01) and ethnicity (1.73) also moderated the effects of treatment on remission.Moreover, adults with more severe depressive symptoms at baseline were more likely to remit after receiving internet-based treatment (OR = 1.19). Guided Internet-based interventions lead to substantial positive treatment effects on treatment response and remission at post-treatment. Thus, such interventions may complement existing services for depression and potentially reduce the gap between the need and provision of evidence-based treatments. Copyright © 2018. Published by Elsevier Ltd.

Novel Treatment Planning of Hemimandibular Hyperplasia by the Use of Three-Dimensional Computer-Aided-Design and Computer-Aided-Manufacturing Technologies.

PubMed

Hatamleh, Muhanad M; Yeung, Elizabeth; Osher, Jonas; Huppa, Chrisopher

2017-05-01

Hemimandibular hyperplasia is characterized by an obvious overgrowth in the size of the mandible on one side, which can extend up to the midline causing facial asymmetry. Surgical resection of the overgrowth depends heavily on the skill and experience of the surgeon. This report describes a novel methodology of applying three-dimensional computer-aided-design and computer-aided-manufacturing principles in improving the outcome of surgery in 2 mandibular hyperplasia patients. Both patients had their cone beam computer tomography (CBCT) scan performed. CMF Pro Plan software (v. 2.1) was used to process the scan data into virtual 3-dimensional models of the maxilla and mandible. Head tilt was adjusted manually by following horizontal reference. Facial asymmetry secondary to mandibular hypertrophy was obvious on frontal and lateral views. Simulation functions were followed including mirror imaging of the unaffected mandibular side into the hyperplastic side and position was optimized by translation and orientation functions. Reconstruction of virtual symmetry was assessed and checked by running 3-dimensional measurements. Then, subtraction functions were used to create a 3-dimensional template defining the outline of the lower mandibular osteotomy needed. Precision of mandibular teeth was enhanced by amalgamating the CBCT scan with e-cast scan of the patient lower teeth. 3-Matic software (v. 10.0) was used in designing cutting guide(s) that define the amount of overgrowth to be resected. The top section of the guide was resting on the teeth hence ensuring stability and accuracy while positioning it. The guide design was exported as an .stl file and printed using in-house 3-dimensional printer in biocompatible resin. Three-dimensional technologies of both softwares (CMF Pro Plan and 3-Matic) are accurate and reliable methods in the diagnosis, treatment planning, and designing of cutting guides that optimize surgical correction of hemimandibular hyperplasia at timely and cost-effect manner.

Science: Grade 7. Interim Guide.

ERIC Educational Resources Information Center

Manitoba Dept. of Education and Training, Winnipeg.

This guide is one of a set of 10 science guides, each covering a separate grade in Manitoba, together covering kindergarten through grade 9. The guides have been designed to provide a framework for building scientific concepts and developing the learning of process skills. They replace an earlier set of guides dated 1979. Each guide is essentially…

Science: Grade 6. Interim Guide.

ERIC Educational Resources Information Center

Manitoba Dept. of Education and Training, Winnipeg.

This guide is one of a set of 10 science guides, each covering a separate grade in Manitoba, together covering kindergarten through grade 9. The guides have been designed to provide a framework for building scientific concepts and developing the learning of process skills. They replace an earlier set of guides dated 1979. Each guide is essentially…

Science: Grade 8. Interim Guide.

ERIC Educational Resources Information Center

Manitoba Dept. of Education and Training, Winnipeg.

This guide is one of a set of 10 science guides, each covering a separate grade in Manitoba, together covering kindergarten through grade 9. The guides have been designed to provide a framework for building scientific concepts and developing the learning of process skills. They replace an earlier set of guides dated 1979. Each guide is essentially…

Science: Grade 2. Interim Guide.

ERIC Educational Resources Information Center

Manitoba Dept. of Education and Training, Winnipeg.

This guide is one of a set of 10 science guides, each covering a separate grade in Manitoba, together covering kindergarten through grade 9. The guides have been designed to provide a framework for building scientific concepts and developing the learning of process skills. They replace an earlier set of guides dated 1979. Each guide is essentially…

Science: Grade 1. Interim Guide.

ERIC Educational Resources Information Center

Manitoba Dept. of Education and Training, Winnipeg.

This guide is one of a set of 10 science guides, each covering a separate grade in Manitoba, together covering kindergarten through grade 9. The guides have been designed to provide a framework for building scientific concepts and developing the learning of process skills. They replace an earlier set of guides dated 1979. Each guide is essentially…

Science: Kindergarten. Interim Guide.

ERIC Educational Resources Information Center

Manitoba Dept. of Education and Training, Winnipeg.

This guide is one of a set of 10 science guides, each covering a separate grade in Manitoba, together covering kindergarten through grade 9. The guides have been designed to provide a framework for building scientific concepts and developing the learning of process skills. They replace an earlier set of guides dated 1979. Each guide is essentially…

Individualized Study Guide on Apiculture: Instructor's Guide. Curriculum Materials for Agricultural Education.

ERIC Educational Resources Information Center

Housmam, John L.; And Others

The instructor's guide is coordinated for use with the student guide. The guide includes suggestions for teacher preparation, equipment and supply needs, suggested references, available audiovisual materials, open-ended questions for classroom discussion, educational opportunities for students, and a form for student evaluation of the study guide.…

GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome.

PubMed

Simovski, Boris; Vodák, Daniel; Gundersen, Sveinung; Domanska, Diana; Azab, Abdulrahman; Holden, Lars; Holden, Marit; Grytten, Ivar; Rand, Knut; Drabløs, Finn; Johansen, Morten; Mora, Antonio; Lund-Andersen, Christin; Fromm, Bastian; Eskeland, Ragnhild; Gabrielsen, Odd Stokke; Ferkingstad, Egil; Nakken, Sigve; Bengtsen, Mads; Nederbragt, Alexander Johan; Thorarensen, Hildur Sif; Akse, Johannes Andreas; Glad, Ingrid; Hovig, Eivind; Sandve, Geir Kjetil

2017-07-01

Recent large-scale undertakings such as ENCODE and Roadmap Epigenomics have generated experimental data mapped to the human reference genome (as genomic tracks) representing a variety of functional elements across a large number of cell types. Despite the high potential value of these publicly available data for a broad variety of investigations, little attention has been given to the analytical methodology necessary for their widespread utilisation. We here present a first principled treatment of the analysis of collections of genomic tracks. We have developed novel computational and statistical methodology to permit comparative and confirmatory analyses across multiple and disparate data sources. We delineate a set of generic questions that are useful across a broad range of investigations and discuss the implications of choosing different statistical measures and null models. Examples include contrasting analyses across different tissues or diseases. The methodology has been implemented in a comprehensive open-source software system, the GSuite HyperBrowser. To make the functionality accessible to biologists, and to facilitate reproducible analysis, we have also developed a web-based interface providing an expertly guided and customizable way of utilizing the methodology. With this system, many novel biological questions can flexibly be posed and rapidly answered. Through a combination of streamlined data acquisition, interoperable representation of dataset collections, and customizable statistical analysis with guided setup and interpretation, the GSuite HyperBrowser represents a first comprehensive solution for integrative analysis of track collections across the genome and epigenome. The software is available at: https://hyperbrowser.uio.no. © The Author 2017. Published by Oxford University Press.

The value of INnovative ICT guided disease management combined with Telemonitoring in OUtpatient clinics for Chronic Heart failure patients. Design and methodology of the IN TOUCH study: a multicenter randomised trial

PubMed Central

2011-01-01

Background Although the value of telemonitoring in heart failure patients is increasingly studied, little is known about the value of the separate components of telehealth: ICT guided disease management and telemonitoring. The aim of this study is to investigate the value of telemonitoring added to ICT guided disease management (DM) on the quality and efficiency of care in patients with chronic heart failure (CHF) after a hospitalisation. Methods/Design The study is divided in two arms; a control arm (DM) and an intervention arm (DM+TM) in 10 hospitals in the Netherlands. In total 220 patients will be included after worsening of CHF (DM: N = 90, DM+TM: N = 130). Total follow-up will be 9 months. Data will be collected at inclusion and then after 2 weeks, 4.5 and 9 months. The primary endpoint of this study is a composite score of: 1: death from any cause during the follow-up of the study, 2: first readmission for HF and 3: change in quality of life compared to baseline, assessed by the Minnesota Living with Heart failure Questionnaire. The study has started in December 2009 and results are expected in 2012. Conclusions The IN TOUCH study is the first to investigate the effect of telemonitoring on top of ICT guided DM on the quality and efficiency of care in patients with worsening HF and will use a composite score as its primary endpoint. Trial registration Netherlands Trial Register (NTR): NTR1898 PMID:21752280

The value of INnovative ICT guided disease management combined with Telemonitoring in OUtpatient clinics for Chronic Heart failure patients. Design and methodology of the IN TOUCH study: a multicenter randomised trial.

PubMed

de Vries, Arjen E; de Jong, Richard M; van der Wal, Martje H L; Jaarsma, Tiny; van Dijk, Rene B; Hillege, Hans L

2011-07-13

Although the value of telemonitoring in heart failure patients is increasingly studied, little is known about the value of the separate components of telehealth: ICT guided disease management and telemonitoring. The aim of this study is to investigate the value of telemonitoring added to ICT guided disease management (DM) on the quality and efficiency of care in patients with chronic heart failure (CHF) after a hospitalisation. The study is divided in two arms; a control arm (DM) and an intervention arm (DM+TM) in 10 hospitals in the Netherlands. In total 220 patients will be included after worsening of CHF (DM: N = 90, DM+TM: N = 130). Total follow-up will be 9 months. Data will be collected at inclusion and then after 2 weeks, 4.5 and 9 months. The primary endpoint of this study is a composite score of: 1: death from any cause during the follow-up of the study, 2: first readmission for HF and 3: change in quality of life compared to baseline, assessed by the Minnesota Living with Heart failure Questionnaire. The study has started in December 2009 and results are expected in 2012. The IN TOUCH study is the first to investigate the effect of telemonitoring on top of ICT guided DM on the quality and efficiency of care in patients with worsening HF and will use a composite score as its primary endpoint. Netherlands Trial Register (NTR): NTR1898.

Criteria for implementing interventions to reduce health inequalities in primary care settings in European regions.

PubMed

Daponte, Antonio; Bernal, Mariola; Bolívar, Julia; Mateo, Inmaculada; Salmi, Louis-Rachid; Barsanti, Sara; Berghmans, Luc; Piznal, Ewelina; Bourgueil, Yann; Marquez, Soledad; González, Ingrid; Carriazo, Ana; Maros-Szabo, Zsuzsanna; Ménival, Solange

2014-12-01

The current social and political context is generating socio-economic inequalities between and within countries, causing and widening health inequalities. The development and implementation of interventions in primary health care (PHC) settings seem unavoidable. Attempts have been made to draw up adequate criteria to guide and evaluate interventions but none for the specific case of PHC. This methodological article aims to contribute to this field by developing and testing a set of criteria for guiding and evaluating real-life interventions to reduce health inequalities in PHC settings in European regions. A literature review, nominal group technique, survey and evaluation template were used to design and test a set of criteria. The questionnaire was answered by professionals in charge of 46 interventions carried out in 12 European countries, and collected detailed information about each intervention. Third-party experts scored the interventions using the set of evaluation criteria proposed. Nine criteria to guide and evaluate interventions were proposed: relevance, appropriateness, applicability, innovation, quality assurance, adequacy of resources, effectiveness in the process, effectiveness in results and mainstreaming. A working definition was drawn up for each one. These criteria were then used to evaluate the interventions identified. The set of criteria drawn up to guide the design, implementation and evaluation of interventions to reduce health inequalities in PHC will be a useful instrument to be applied to interventions under development for culturally, politically and socio-economically diverse PHC contexts throughout Europe. © The Author 2014. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

Spectrum of intra-thoracic lesion detected by computed tomography guided fine needle aspiration biopsy

PubMed Central

2013-01-01

Background Fine needle aspiration biopsy (FNAB) is a rapid, sensitive and inexpensive procedure for diagnosing benign and malignant palpable lesions. For lesions that are not palpable or deep seated, FNAB can be performed under the guidance of radiological imaging. Our basic objective was to evaluate the spectrum of intrathoracic lesions by using Computed Tomography guided fine needle aspiration biopsy and evaluate its diagnostic yield. Methodology It was a retrospective study carried out in the Department of Histopathology, Liaquat National Hospital and Medical College, during the months of August 2011 and August 2012. All patients with pulmonary, mediastinal or paravertebral mass who underwent CT guided intrathoracic biopsy were included in this study. Fine needle aspiration biopsies were performed in the Radiology Department and specimen retrieved was sent in 10% buffered Formalin to the Histopathology Department. All the data was entered and analyzed through SPSS 19.0. Results A total of 130 cases were evaluated, out of which 108 (83.1%) were pulmonary, 16 (12.3%) were mediastinal and 6 (4.6%) were paravertebral. Conclusive biopsies were possible in 113 cases, while 17 biopsies were inconclusive. In those that showed a conclusive diagnosis, 83.1% were neoplastic and 16.9% were non neoplastic. Of the neoplastic cases, 27 (20.8%) were adenocarcinomas, followed by squamous cell carcinomas (15.4%) and large cell carcinoma, not otherwise specified, (12.3%). Conclusion CT guided fine needle aspiration biopsy is a reliable tool for examination of intrathoracic lesions, with a high rate of conclusive diagnosis. PMID:23402220

Use of the cumulative sum method (CUSUM) to assess the learning curves of ultrasound-guided continuous femoral nerve block.

PubMed

Kollmann-Camaiora, A; Brogly, N; Alsina, E; Gilsanz, F

2017-10-01

Although ultrasound is a basic competence for anaesthesia residents (AR) there is few data available on the learning process. This prospective observational study aims to assess the learning process of ultrasound-guided continuous femoral nerve block and to determine the number of procedures that a resident would need to perform in order to reach proficiency using the cumulative sum (CUSUM) method. We recruited 19 AR without previous experience. Learning curves were constructed using the CUSUM method for ultrasound-guided continuous femoral nerve block considering 2 success criteria: a decrease of pain score>2 in a [0-10] scale after 15minutes, and time required to perform it. We analyse data from 17 AR for a total of 237 ultrasound-guided continuous femoral nerve blocks. 8/17 AR became proficient for pain relief, however all the AR who did more than 12 blocks (8/8) became proficient. As for time of performance 5/17 of AR achieved the objective of 12minutes, however all the AR who did more than 20 blocks (4/4) achieved it. The number of procedures needed to achieve proficiency seems to be 12, however it takes more procedures to reduce performance time. The CUSUM methodology could be useful in training programs to allow early interventions in case of repeated failures, and develop competence-based curriculum. Copyright © 2017 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

Orthogonal ion injection apparatus and process

DOEpatents

Kurulugama, Ruwan T; Belov, Mikhail E

2014-04-15

An orthogonal ion injection apparatus and process are described in which ions are directly injected into an ion guide orthogonal to the ion guide axis through an inlet opening located on a side of the ion guide. The end of the heated capillary is placed inside the ion guide such that the ions are directly injected into DC and RF fields inside the ion guide, which efficiently confines ions inside the ion guide. Liquid droplets created by the ionization source that are carried through the capillary into the ion guide are removed from the ion guide by a strong directional gas flow through an inlet opening on the opposite side of the ion guide. Strong DC and RF fields divert ions into the ion guide. In-guide orthogonal injection yields a noise level that is a factor of 1.5 to 2 lower than conventional inline injection known in the art. Signal intensities for low m/z ions are greater compared to convention inline injection under the same processing conditions.

Your Starting Guide To Childhood Apraxia of Speech

MedlinePlus

... About Apraxia Apraxia-KIDS Library Family Start Guide SLP Start Guide Apraxia Information Downloads Research Symposium Videos ... About Apraxia Apraxia-KIDS Library Family Start Guide SLP Start Guide Research Symposium Videos On-Demand Webinars ...

4-H Horticulture Project Activity Guides. Leader's Guide and Units 1-3.

ERIC Educational Resources Information Center

Illinois Univ., Urbana. Cooperative Extension Service.

This document, concerning the 4-H horticulture project, includes a leader's guide and three youth activity guides. The leader's guide can be used to plan group project meetings that are both fun and educational. Activities can be adapted to various age groups. The leader's guide includes basic information for growing plants indoors and outdoors,…

Training Cambodian Village Health Support Guides in Diabetes Prevention: Effects on Guides' Knowledge and Teaching Activities Over 6 Months.

PubMed

Wagner, Julie; Keuky, Lim; Fraser-King, Lorraine; Kuoch, Theanvy; Scully, Mary

2016-04-01

Type 2 diabetes is a pressing public health concern in Cambodia, a country with limited human resource capacity due to genocide. Cambodian village health support guides (Guides) promote health at the local level. This paper reports preliminary results of training Guides in diabetes prevention. The curriculum, called Eat, Walk, Sleep was delivered to Guides in Siem Reap province once over 3 h. Participants completed a pretest and posttest on diabetes knowledge. Guides were offered continuing education through Eat, Walk, Sleep resources and were encouraged to teach Eat, Walk, Sleep in their villages. For each of 6 months following their training, Guides completed a checklist regarding their activities. One hundred eighty-five Guides attended one of ten trainings. Knowledge scores increased significantly from pretest to posttest. During 6 months of follow-up, n = 159 Guides (85 %) completed at least one monthly checklist. Guides reported high rates of uptake and delivery of the Eat, Walk, Sleep curriculum and moderate rates of continuing education about diabetes. Diabetes prevention in Cambodia is nascent. Guides show excellent uptake and dissemination of the curriculum. Future research should examine effect of support for Guide activities and the effect of the curriculum on villager health behaviors, and ultimately, on rates of type 2 diabetes.

Applications of decision analysis and related techniques to industrial engineering problems at KSC

NASA Technical Reports Server (NTRS)

Evans, Gerald W.

1995-01-01

This report provides: (1) a discussion of the origination of decision analysis problems (well-structured problems) from ill-structured problems; (2) a review of the various methodologies and software packages for decision analysis and related problem areas; (3) a discussion of how the characteristics of a decision analysis problem affect the choice of modeling methodologies, thus providing a guide as to when to choose a particular methodology; and (4) examples of applications of decision analysis to particular problems encountered by the IE Group at KSC. With respect to the specific applications at KSC, particular emphasis is placed on the use of the Demos software package (Lumina Decision Systems, 1993).

[Progress in methodological characteristics of clinical practice guideline for osteoarthritis].

PubMed

Xing, D; Wang, B; Lin, J H

2017-06-01

At present, several clinical practice guidelines for the treatment of osteoarthritis have been developed by institutes or societies. The ultimate purpose of developing clinical practice guidelines is to formulate the process in the treatment of osteoarthritis effectively. However, the methodologies used in developing clinical practice guidelines may place an influence on the transformation and application of that in treating osteoarthritis. The present study summarized the methodological features of individual clinical practice guideline and presented the tools for quality evaluation of clinical practice guideline. The limitations of current osteoarthritis guidelines of China are also indicated. The review article might help relevant institutions improve the quality in developing guide and clinical transformation.

RPP-PRT-58489, Revision 1, One Systems Consistent Safety Analysis Methodologies Report. 24590-WTP-RPT-MGT-15-014

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gupta, Mukesh; Niemi, Belinda; Paik, Ingle

2015-09-02

In 2012, One System Nuclear Safety performed a comparison of the safety bases for the Tank Farms Operations Contractor (TOC) and Hanford Tank Waste Treatment and Immobilization Plant (WTP) (RPP-RPT-53222 / 24590-WTP-RPT-MGT-12-018, “One System Report of Comparative Evaluation of Safety Bases for Hanford Waste Treatment and Immobilization Plant Project and Tank Operations Contract”), and identified 25 recommendations that required further evaluation for consensus disposition. This report documents ten NSSC approved consistent methodologies and guides and the results of the additional evaluation process using a new set of evaluation criteria developed for the evaluation of the new methodologies.

Wave guide impedance matching method and apparatus

DOEpatents

Kronberg, James W.

1990-01-01

A technique for modifying the end portion of a wave guide, whether hollow or solid, carrying electromagnetic, acoustic or optical energy, to produce a gradual impedance change over the length of the end portion, comprising the cutting of longitudinal, V-shaped grooves that increase in width and depth from beginning of the end portion of the wave guide to the end of the guide so that, at the end of the guide, no guide material remains and no surfaces of the guide as modified are perpendicular to the direction of energy flow. For hollow guides, the grooves are cut beginning on the interior surface; for solid guides, the grooves are cut beginning on the exterior surface. One or more resistive, partially conductive or nonconductive sleeves can be placed over the exterior of the guide and through which the grooves are cut to smooth the transition to free space.

Stemless ball valve

NASA Technical Reports Server (NTRS)

Burgess, Kevin (Inventor); Yakos, David (Inventor); Walthall, Bryan (Inventor)

2012-01-01

A stemless ball valve comprising: a right flange; left flange; ball with an axis pin and two travel pins; ball seal on either side of the ball; guide sleeve with inner walls comprising two channels; cartridge guide holder; inner magnetic cartridge; and outer magnetic cartridge. The ball is situated inside of the guide sleeve, and a travel pin is located in each of the two channels. The guide sleeve is situated inside of the cartridge guide holder, which is located adjacent to and outside of the inner magnetic cartridge and secured to the inner magnetic cartridge such that when the inner magnetic cartridge rotates, the cartridge guide holder also rotates. The cartridge guide holder is secured to the guide sleeve such that when the cartridge guide holder rotates, the travel pins move within the channels in the inner walls of the guide sleeve, thereby causing the ball to rotate.

Comparison of fine-needle aspiration and core needle biopsy under ultrasonographic guidance for detecting malignancy and for the tissue-specific diagnosis of salivary gland tumors.

PubMed

Eom, H-J; Lee, J H; Ko, M-S; Choi, Y J; Yoon, R G; Cho, K J; Nam, S Y; Baek, J H

2015-06-01

Diagnostic test accuracy studies for ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy have shown inconclusive results due to their heterogenous study designs. Our aim was to compare the diagnostic accuracy of ultrasonography-guided fine-needle aspiration versus ultrasonography-guided core needle biopsy for detecting malignant tumors of the salivary gland and for the tissue-specific diagnosis of salivary gland tumors in a single tertiary hospital. This retrospective study was approved by our institutional review board and informed consent was waived. Four hundred twelve patients who underwent ultrasonography-guided fine-needle aspiration (n = 155) or ultrasonography-guided core needle biopsy (n = 257) with subsequent surgical confirmation or clinical follow-up were enrolled. We compared the diagnostic accuracy of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy regarding malignant salivary gland tumors and the correct tissue-specific diagnosis of benign and malignant tumors. We also tested the difference between these procedures according to the operator's experience and lesion characteristics. The inconclusive rates of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy were 19% and 4%, respectively (P < .001). The overall accuracy of ultrasonography-guided core needle biopsy for diagnosing malignant tumors was significantly higher than that of ultrasonography-guided fine-needle aspiration (P = .024). The correct tissue-specific diagnosis rates of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy were 95% versus 97% for benign tumors (P = .648) and 67% versus 80% for malignant tumors (P = .310). Trainees showed significantly lower accuracy with ultrasonography-guided fine-needle aspiration than with ultrasonography-guided core needle biopsy for diagnosing malignant tumors (P = .021). There was no difference between the diagnostic accuracy of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy according to the internal composition of the lesions. There were no complications requiring intervention or hospitalization in our patients. Ultrasonography-guided core needle biopsy is superior to ultrasonography-guided fine-needle aspiration in detecting and characterizing malignant tumors of the salivary gland and could emerge as the diagnostic method of choice for patients presenting with a salivary gland mass. © 2015 by American Journal of Neuroradiology.

"Family Guides" to Timely Topics in Space Science

NASA Astrophysics Data System (ADS)

Morrow, C.; McLain, B.; Wilkerson, A.; Garvin-Doxas, K.; Dyches, P.

We have undertaken the development, field testing, and dissemination of a new series of ``Family Guides'' on timely topics of notable interest in space science and astronomy. Each Guide includes an innovative collection of puzzles, pictures, poetry, and projects, all designed to stimulate enjoyable co-learning, inquiry-based experiences between kids aged 6-12 and the caring adults in their lives. The Guides are primarily intended for use in informal educational settings, including at home, with after-school programs, in youth groups, and in programs for children, school-groups, or families that are conducted in museums, planetariums, and nature centers. We are learning that classroom teachers also express interest in the Guide's activities as a means to engage students attention toward more formal lessons. The Guides endeavor to be accessible to those who are not familiar with astronomy. They provide background on questions commonly asked by children. The interactive activities challenge common misconceptions. The Guides' also coach adults how to lead inquiry with kids instead of telling or prescribing answers. The Guides' resource sections provide leads to more information and additional products related to family learning. We released the field test version of the Family Guide to the Sun in late summer 2003. In January 2004 we released the field test version of the Family Guide to Mars in time for use with educational programs associated with the Mars Exploration Rover landings. We are in the planning stages for a Family Guide to Saturn and for a Family Guide to the Search for Life Elsewhere. These later Guides will build on the base of understanding we construct from the field testing of the earlier Guides. This paper will provide details of the Guides' contents as well as results from field testing in various educational settings. We are proposing for funds to translate the Family Guide to Mars and the Family Guide the Sun into both French and Spanish.

Psychological impact of abortion: methodological and outcomes summary of empirical research between 1966 and 1988.

PubMed

Rogers, J L; Stoms, G B; Phifer, J L

1989-01-01

A systematic "roadmap" through the medical literature that empirically examines the incidence of psychological sequelae of induced abortion is presented. Because outcome incidence rates and methodological profiles vary substantially across studies, selective use of articles from this literature without an accompanying rationale for that selectivity could foster erroneous conclusions. Information compiled here can facilitate a rapid methodological critique of citations in abortion-related materials. Investigations published in English between January 1966 and April 1988 that quantitatively examined psychological sequelae using prospective, retrospective, or comparative methodologies are summarized in tables to produce a synopsis of the demographics, methodological limitations, and gross statistical features of each article. This quantitative guide is designed to facilitate appropriate use of the current literature, provide needed background to assess positions arising from the currently available data, and provide methodological focus for planning better studies in the future.

14 CFR 1203.412 - Classification guides.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Classification guides. 1203.412 Section... PROGRAM Guides for Original Classification § 1203.412 Classification guides. (a) General. A classification guide, based upon classification determinations made by appropriate program and classification...

14 CFR 1203.412 - Classification guides.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Classification guides. 1203.412 Section... PROGRAM Guides for Original Classification § 1203.412 Classification guides. (a) General. A classification guide, based upon classification determinations made by appropriate program and classification...

14 CFR 1203.412 - Classification guides.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Classification guides. 1203.412 Section 1203... Guides for Original Classification § 1203.412 Classification guides. (a) General. A classification guide, based upon classification determinations made by appropriate program and classification authorities...

UKIRT fast guide system improvements

NASA Astrophysics Data System (ADS)

Balius, Al; Rees, Nicholas P.

1997-09-01

The United Kingdom Infra-Red Telescope (UKIRT) has recently undergone the first major upgrade program since its construction. One part of the upgrade program was an adaptive tip-tilt secondary mirror closed with a CCD system collectively called the fast guide system. The installation of the new secondary and associated systems was carried out in the first half of 1996. Initial testing of the fast guide system has shown great improvement in guide accuracy. The initial installation included a fixed integration time CCD. In the first part of 1997 an integration time controller based on computed guide star luminosity was implemented in the fast guide system. Also, a Kalman type estimator was installed in the image tracking loop based on a dynamic model and knowledge of the statistical properties of the guide star position error measurement as a function of computed guide star magnitude and CCD integration time. The new configuration was tested in terms of improved guide performance nd graceful degradation when tracking faint guide stars. This paper describes the modified fast guide system configuration and reports the results of performance tests.

Ultrasound-guided fine needle aspiration versus core needle biopsy: comparison of post-biopsy hematoma rates and risk factors.

PubMed

Chae, In Hye; Kim, Eun-Kyung; Moon, Hee Jung; Yoon, Jung Hyun; Park, Vivian Y; Kwak, Jin Young

2017-07-01

To compare post-biopsy hematoma rates between ultrasound guided-fine needle aspiration and ultrasound guided-core needle biopsy, and to investigate risk factors for post-biopsy hematoma. A total of 5304 thyroid nodules which underwent ultrasound guided biopsy were included in this retrospective study. We compared clinical and US features between patients with and without post-biopsy hematoma. Associations between these features and post-biopsy hematoma were analyzed. Post-biopsy hematoma rate was 0.8% (43/5121) for ultrasound guided-fine needle aspiration and 4.9% (9/183) for ultrasound guided-core needle biopsy (P < 0.001). For ultrasound guided-fine needle aspiration, gender, age, size, presence of vascularity, and suspicious US features were not associated with post-biopsy hematoma according to experience level. Post-biopsy hematoma occurred significantly more with ultrasound guided-core needle biopsy (9/179, 5.0%) than with ultrasound guided-fine needle aspiration (9/1138, 0.8%) (P < 0.001) in experienced performers and ultrasound guided-core needle biopsy was the only significant risk factor for post-biopsy hematoma (adjusted Odds Ratio, 6.458, P < 0.001). Post-biopsy hematoma occurred significantly more in ultrasound guided-core needle biopsy than in ultrasound guided-fine needle aspiration and ultrasound guided-core needle biopsy was the only independent factor of post-biopsy hematoma in thyroid nodules.

COATING ALTERNATIVES GUIDE (CAGE) USER'S GUIDE

EPA Science Inventory

The guide provides instructions for using the Coating Alternatives GuidE (CAGE) software program, version 1.0. It assumes that the user is familiar with the fundamentals of operating an IBM-compatible personal computer (PC) under the Microsoft disk operating system (MS-DOS). CAGE...

SAGE 2.1: SOLVENT ALTERNATIVES GUIDE: USER'S GUIDE

EPA Science Inventory

The guide provides instruction for using the SAGE (Solvent Alternatives GuidE) software system, version 2.1. SAGE recommends solvent replacements in cleaning and degreasing operations. It leads the user through a question-and-answer session. The user's responses allow the system ...

The use and evaluation of study guides with middle school students.

PubMed

Farnum, M; Brigham, T A

1978-01-01

Two experiments were conducted with 24 fifth-grade students participating. In the first experiment, quiz performance with study guides was compared to quiz performance without study guides. The group whose students received study guides always scored higher than the group who did not receive study guides. Experiment II assessed the feasibility of students scoring their own study guides. The reliability of student scoring was found to be 93% over all study guides and there were no significant differences between "self-scored" and "teacher-scored" groups on the weekly quizzes.

Apparatus and method of dissociating ions in a multipole ion guide

DOEpatents

Webb, Ian K.; Tang, Keqi; Smith, Richard D.; Ibrahim, Yehia M.; Anderson, Gordon A.

2014-07-08

A method of dissociating ions in a multipole ion guide is disclosed. A stream of charged ions is supplied to the ion guide. A main RF field is applied to the ion guide to confine the ions through the ion guide. An excitation RF field is applied to one pair of rods of the ion guide. The ions undergo dissociation when the applied excitation RF field is resonant with a secular frequency of the ions. The multipole ion guide is, but not limited to, a quadrupole, a hexapole, and an octopole.

Image guided versus palpation guided core needle biopsy of palpable breast masses: a prospective study

PubMed Central

Hari, Smriti; Kumari, Swati; Srivastava, Anurag; Thulkar, Sanjay; Mathur, Sandeep; Veedu, Prasad Thotton

2016-01-01

Background & objectives: Biopsy of palpable breast masses can be performed manually by palpation guidance or under imaging guidance. Based on retrospective studies, image guided biopsy is considered more accurate than palpation guided breast biopsy; however, these techniques have not been compared prospectively. We conducted this prospective study to verify the superiority and determine the size of beneficial effect of image guided biopsy over palpation guided biopsy. Methods: Over a period of 18 months, 36 patients each with palpable breast masses were randomized into palpation guided and image guided breast biopsy arms. Ultrasound was used for image guidance in 33 patients and mammographic (stereotactic) guidance in three patients. All biopsies were performed using 14 gauge automated core biopsy needles. Inconclusive, suspicious or imaging-histologic discordant biopsies were repeated. Results: Malignancy was found in 30 of 36 women in palpation guided biopsy arm and 27 of 36 women in image guided biopsy arm. Palpation guided biopsy had sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 46.7, 100, 100, 27.3 per cent, respectively, for diagnosing breast cancer. Nineteen of 36 women (52.8%) required repeat biopsy because of inadequate samples (7 of 19), suspicious findings (2 of 19) or imaging-histologic discordance (10 of 19). On repeat biopsy, malignancy was found in all cases of imaging-histologic discordance. Image guided biopsy had 96.3 per cent sensitivity and 100 per cent specificity. There was no case of inadequate sample or imaging-histologic discordance with image guided biopsy. Interpretation & conclusions: Our results showed that in palpable breast masses, image guided biopsy was superior to palpation guided biopsy in terms of sensitivity, false negative rate and repeat biopsy rates. PMID:27488003

Shade guide optimization--a novel shade arrangement principle for both ceramic and composite shade guides when identifying composite test objects.

PubMed

Østervemb, Niels; Jørgensen, Jette Nedergaard; Hørsted-Bindslev, Preben

2011-02-01

The most widely used shade guide for composite materials is made of ceramic and arranged according to a non-proven method. There is a need for a composite shade guide using a scientifically based arrangement principle. To compare the shade tab arrangement of the Vitapan Classical shade guide and an individually made composite shade guide using both the originally proposed arrangement principle and arranged according to ΔE2000 values with hue group division. An individual composite shade guide made from Filtek Supreme XT body colors was compared to the Vitapan Classical shade guide. Twenty-five students matched color samples made from Filtek Supreme XT body colors using the two shade guides arranged after the two proposed principles--four shade guides in total. Age, sequence, gender, time, and number of correct matches were recorded. The proposed visually optimal composite shade guide was both fastest and had the highest number of correct matches. Gender was significantly associated with time used for color sampling but not regarding the number of correct shade matches. A composite shade guide is superior compared to the ceramic Vitapan Classical guide when using composite test objects. A rearrangement of the shade guide according to hue, subdivided according to ΔE2000, significantly reduces the time needed to take a color sample and increases the number of correct shade matches. Total color difference in relation to the lightest tab with hue group division is recommended as a possible and universally applicable mode of tab arrangement in dental color standards. Moreover, a shade guide made of the composite materials itself is to be preferred as both a faster and more accurate method of determining color. © 2011, COPYRIGHT THE AUTHORS. JOURNAL COMPILATION © 2011, WILEY PERIODICALS, INC.

A Guide to the Literature on Learning Graphical Models

NASA Technical Reports Server (NTRS)

Buntine, Wray L.; Friedland, Peter (Technical Monitor)

1994-01-01

This literature review discusses different methods under the general rubric of learning Bayesian networks from data, and more generally, learning probabilistic graphical models. Because many problems in artificial intelligence, statistics and neural networks can be represented as a probabilistic graphical model, this area provides a unifying perspective on learning. This paper organizes the research in this area along methodological lines of increasing complexity.

A Methodology for Performing Effects-Based Assessments

DTIC Science & Technology

2006-03-01

can then be used to make assessments (Smith, 2002:384). 2.8 Cause-and-Effect Diagrams Developed by Dr. Kaoru Ishikawa in the field of Quality Control...John Wiley & Sons, Inc., 2004. Ishikawa , Kaoru . Guide to Quality Control. White Plains NY: Asian Productivity Organization, 1989...various causes affecting product quality by sorting out and relating the causes. Cause-and-effect diagrams are sometimes called Ishikawa diagrams, or

A Methodological Study Evaluating a Pretutorial Computer-Compiled Instructional Program in High School Physics Instruction Initiated from Student-Teacher Selected Instructional Objectives. Final Report.

ERIC Educational Resources Information Center

Leonard, B. Charles; Denton, Jon J.

A study sought to develop and evaluate an instructional model which utilized the computer to produce individually prescribed instructional guides to account for the idiosyncratic variations among students in physics classes at the secondary school level. The students in the treatment groups were oriented toward the practices of selecting…

Doing Quantitative Research in Education with SPSS Second edition Daniel Muijs Doing Quantitative Research in Education with SPSS Second edition £24.99 264pp 9781849203241 1849203245 [Formula: see text].

PubMed

2012-07-19

THIS TEXT is a straightforward, no nonsense guide for novice researchers venturing into research involving quantitative methodologies. It is also an excellent resource to refresh more experienced researchers. It is well written in plain English and encourages researchers to carry out their own analyses.

Maori Children's Biliteracy Experiences Moving from a Kohanga Reo Setting to a Kura Kaupapa Maori, Bilingual, and Mainstream Education Setting: An Exploratory Study

ERIC Educational Resources Information Center

Rona, Sarika; McLachlan, Claire J.

2018-01-01

This research explored the biliteracy experiences of three kohanga reo children as they started school in one of three school settings: a bilingual unit, a mainstream classroom, and kura kaupapa Maori. A Kaupapa Maori approach underpinned this research and guided the case study methodology employed. The children's literacy experiences were…

End-of-Life Care and Dying: Issues Raised by Staff Supporting Older People with Intellectual Disability in Community Living Services

ERIC Educational Resources Information Center

Wiese, Michele; Stancliffe, Roger J.; Balandin, Susan; Howarth, Glennys; Dew, Angela

2012-01-01

Background: The aim of this study was to explore the current status of end-of-life care and dying of people with intellectual disability based on the experiences of staff in community living services. Materials and Methods: Focus groups and individual interviews were conducted, guided by grounded theory methodology. Results: The current status of…

Quality of Malaysian Teachers Based on Education and Training: A Benefit and Earnings Returns Analysis Using Human Capital Theory

ERIC Educational Resources Information Center

Ismail, Ramlee; Awang, Marinah

2017-01-01

Purpose: The purpose of this paper is to investigate how the quality of teachers based on education and training provided under new reform policies in Malaysia affects their earnings outcomes. The study conducted a benefit and returns analysis guided by human capital theory. Design/methodology/approach: The study used survey research methods to…

An Empirical Methodology for Engineering Human Systems Integration

DTIC Science & Technology

2009-12-01

scanning critical information and selectively skipping what is not important for the immediate task. This learned skill is called a proper “cross check...ability to recover from errors. Efficiency: the level of productivity that can be achieved once learning has occurred. 162 Learnability: the...use, to legacy systems. Knowing what design issues have plagued past operators can guide the generation of requirements to address the identified

An Examination of One-to-One Computing in the Middle School: Does Increased Access Bring about Increased Student Engagement?

ERIC Educational Resources Information Center

Donovan, Loretta; Green, Tim; Hartley, Kendall

2010-01-01

This study explores configurations of laptop use in a one-to-one environment. Guided by methodologies of the Concerns-Based Adoption Model of change, an Innovation Configuration Map (description of the multiple ways an innovation is implemented) of a 1:1 laptop program at a middle school was developed and analyzed. Three distinct configurations…

Immersion francaise precoce: Arts plastiques 1-7 (Early French Immersion: Plastic Arts for Grades 1-7).

ERIC Educational Resources Information Center

Burt, Andy; And Others

This curriculum guide in art education is intended for use in grades 1-7 in the early French immersion program. An introductory chapter describes the educational objectives of the art program, the role of art education in child development, general and terminal objectives, methodology, the steps in graphic evolution, and an outline of the program.…

Research on and Guidelines for Effective Use of Assessment Instruments and Strategies for Adult Learners Enrolled in Adult Basic and Literacy Education Programs. Final Report.

ERIC Educational Resources Information Center

Pennsylvania State Univ., University Park. Inst. for the Study of Adult Literacy.

The goal of this research project was to create a guide on the effective use of assessment instruments and methodologies, related resources, and guidelines for measuring adult learners' attainment of basic skills and competencies to document educational gains and demonstrate program quality. The project focused on confirming current use of…

Multinational Experiment 7. Outcome 4: Methodology to Understand Inter-Domain Dependencies and Vulnerabilities Guide v. 1.0

DTIC Science & Technology

2013-01-31

the methodology had reached its full maturity and proposed a number of changes, mainly pertaining to its clarification. Recommendations stemming from...34’ "’ ’iii ao > c:iij ·- c: N 8: c( "’ "’ .!! ::?i Qj ::::s "’ ’u ~ c. c: O :c~ l£ c: ~ .Q 8. M Cll ::::J ~ 0 ~ ... Qj ..!!!c ~9 c...example, the analyst should be able to superimpose or switch from the C2 Kmap to the intelligence Kmap when he or she works on the dependencies stemming

Epistasis analysis using artificial intelligence.

PubMed

Moore, Jason H; Hill, Doug P

2015-01-01

Here we introduce artificial intelligence (AI) methodology for detecting and characterizing epistasis in genetic association studies. The ultimate goal of our AI strategy is to analyze genome-wide genetics data as a human would using sources of expert knowledge as a guide. The methodology presented here is based on computational evolution, which is a type of genetic programming. The ability to generate interesting solutions while at the same time learning how to solve the problem at hand distinguishes computational evolution from other genetic programming approaches. We provide a general overview of this approach and then present a few examples of its application to real data.

Speaking for ourselves: feminist methods and community psychology.

PubMed

Cosgrove, L; McHugh, M C

2000-12-01

Although feminist and community psychology share a number of epistemological and methodological perspectives that guide their respective theories and research practices, it has been argued that community psychology has not fully integrated a feminist perspective into the discipline. This paper examines how community psychology and feminist research methods might combine to help us better understand women's experiences without essentializing or universalizing those experiences. The authors offer a series of suggested directions for feminist research that may also prove promising for community psychology. Particular attention is paid to feminist social constructionist approaches insofar as they address the complex relationship between epistemology and methodology.

An overview of the dynamic calibration of piezoelectric pressure transducers

NASA Astrophysics Data System (ADS)

Theodoro, F. R. F.; Reis, M. L. C. C.; d’ Souto, C.

2018-03-01

Dynamic calibration is a research area that is still under development and is of great interest to aerospace and automotive industries. This study discusses some concepts regarding dynamic measurements of pressure quantities and presents an overview of dynamic calibration of pressure transducers. Studies conducted by the Institute of Aeronautics and Space focusing on research regarding piezoelectric pressure transducer calibration in shock tube are presented. We employed the Guide to the Expression of Uncertainty and a Monte Carlo Method in the methodology. The results show that both device and methodology employed are adequate to calibrate the piezoelectric sensor.

Routine Clinical Quantitative Rest Stress Myocardial Perfusion for Managing Coronary Artery Disease: Clinical Relevance of Test-Retest Variability.

PubMed

Kitkungvan, Danai; Johnson, Nils P; Roby, Amanda E; Patel, Monika B; Kirkeeide, Richard; Gould, K Lance

2017-05-01

Positron emission tomography (PET) quantifies stress myocardial perfusion (in cc/min/g) and coronary flow reserve to guide noninvasively the management of coronary artery disease. This study determined their test-retest precision within minutes and daily biological variability essential for bounding clinical decision-making or risk stratification based on low flow ischemic thresholds or follow-up changes. Randomized trials of fractional flow reserve-guided percutaneous coronary interventions established an objective, quantitative, outcomes-driven standard of physiological stenosis severity. However, pressure-derived fractional flow reserve requires invasive coronary angiogram and was originally validated by comparison to noninvasive PET. The time course and test-retest precision of serial quantitative rest-rest and stress-stress global myocardial perfusion by PET within minutes and days apart in the same patient were compared in 120 volunteers undergoing serial 708 quantitative PET perfusion scans using rubidium 82 (Rb-82) and dipyridamole stress with a 2-dimensional PET-computed tomography scanner (GE DST 16) and University of Texas HeartSee software with our validated perfusion model. Test-retest methodological precision (coefficient of variance) for serial quantitative global myocardial perfusion minutes apart is ±10% (mean ΔSD at rest ±0.09, at stress ±0.23 cc/min/g) and for days apart is ±21% (mean ΔSD at rest ±0.2, at stress ±0.46 cc/min/g) reflecting added biological variability. Global myocardial perfusion at 8 min after 4-min dipyridamole infusion is 10% higher than at standard 4 min after dipyridamole. Test-retest methodological precision of global PET myocardial perfusion by serial rest or stress PET minutes apart is ±10%. Day-to-different-day biological plus methodological variability is ±21%, thereby establishing boundaries of variability on physiological severity to guide or follow coronary artery disease management. Maximum stress increases perfusion and coronary flow reserve, thereby reducing potentially falsely low values mimicking ischemia. Copyright © 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

An open-source framework for testing tracking devices using Lego Mindstorms

NASA Astrophysics Data System (ADS)

Jomier, Julien; Ibanez, Luis; Enquobahrie, Andinet; Pace, Danielle; Cleary, Kevin

2009-02-01

In this paper, we present an open-source framework for testing tracking devices in surgical navigation applications. At the core of image-guided intervention systems is the tracking interface that handles communication with the tracking device and gathers tracking information. Given that the correctness of tracking information is critical for protecting patient safety and for ensuring the successful execution of an intervention, the tracking software component needs to be thoroughly tested on a regular basis. Furthermore, with widespread use of extreme programming methodology that emphasizes continuous and incremental testing of application components, testing design becomes critical. While it is easy to automate most of the testing process, it is often more difficult to test components that require manual intervention such as tracking device. Our framework consists of a robotic arm built from a set of Lego Mindstorms and an open-source toolkit written in C++ to control the robot movements and assess the accuracy of the tracking devices. The application program interface (API) is cross-platform and runs on Windows, Linux and MacOS. We applied this framework for the continuous testing of the Image-Guided Surgery Toolkit (IGSTK), an open-source toolkit for image-guided surgery and shown that regression testing on tracking devices can be performed at low cost and improve significantly the quality of the software.

Biochemometrics for Natural Products Research: Comparison of Data Analysis Approaches and Application to Identification of Bioactive Compounds.

PubMed

Kellogg, Joshua J; Todd, Daniel A; Egan, Joseph M; Raja, Huzefa A; Oberlies, Nicholas H; Kvalheim, Olav M; Cech, Nadja B

2016-02-26

A central challenge of natural products research is assigning bioactive compounds from complex mixtures. The gold standard approach to address this challenge, bioassay-guided fractionation, is often biased toward abundant, rather than bioactive, mixture components. This study evaluated the combination of bioassay-guided fractionation with untargeted metabolite profiling to improve active component identification early in the fractionation process. Key to this methodology was statistical modeling of the integrated biological and chemical data sets (biochemometric analysis). Three data analysis approaches for biochemometric analysis were compared, namely, partial least-squares loading vectors, S-plots, and the selectivity ratio. Extracts from the endophytic fungi Alternaria sp. and Pyrenochaeta sp. with antimicrobial activity against Staphylococcus aureus served as test cases. Biochemometric analysis incorporating the selectivity ratio performed best in identifying bioactive ions from these extracts early in the fractionation process, yielding altersetin (3, MIC 0.23 μg/mL) and macrosphelide A (4, MIC 75 μg/mL) as antibacterial constituents from Alternaria sp. and Pyrenochaeta sp., respectively. This study demonstrates the potential of biochemometrics coupled with bioassay-guided fractionation to identify bioactive mixture components. A benefit of this approach is the ability to integrate multiple stages of fractionation and bioassay data into a single analysis.

Understanding male cancer patients' barriers to participating in cancer rehabilitation.

PubMed

Handberg, C; Lomborg, K; Nielsen, C V; Oliffe, J L; Midtgaard, J

2015-11-01

The aim was to describe male cancer survivors' barriers towards participation in cancer rehabilitation as a means to guiding future targeted men's cancer rehabilitation. Symbolic Interactionism along with the interpretive descriptive methodology guided the study of 35 male cancer survivors representing seven cancer types. Data were generated through a 5-month fieldwork study comprising participant observations, semi-structured individual interviews and informal conversations. The analyses revealed two overarching findings shedding light on male cancer survivors' barriers to rehabilitation: 'Fear of losing control' and 'Striving for normality'. While 'Fear of losing control' signified what the men believed rehabilitation would invoke: 'Reduced manliness', 'Sympathy and dependency' and 'Confrontation with death', 'Striving for normality' was based on what the men believed rehabilitation would hinder: 'Autonomy and purpose', 'Solidarity and fellowship' and 'Forget and move on'. This study of male cancer survivors' and cancer rehabilitation documents how masculine ideals may constitute barriers for participation in rehabilitation and provides insights about why men are underrepresented in rehabilitation. The findings can guide practice to develop research-based rehabilitation approaches focused on preserving control and normality. Further empirical evidence is needed to: (1) explore the conduct of health professionals' towards male cancer patients and (2) address gender inequalities in cancer rehabilitation. © 2015 John Wiley & Sons Ltd.

From screening to synthesis: using nvivo to enhance transparency in qualitative evidence synthesis.

PubMed

Houghton, Catherine; Murphy, Kathy; Meehan, Ben; Thomas, James; Brooker, Dawn; Casey, Dympna

2017-03-01

To explore the experiences and perceptions of healthcare staff caring for people with dementia in the acute setting. This article focuses on the methodological process of conducting framework synthesis using nvivo for each stage of the review: screening, data extraction, synthesis and critical appraisal. Qualitative evidence synthesis brings together many research findings in a meaningful way that can be used to guide practice and policy development. For this purpose, synthesis must be conducted in a comprehensive and rigorous way. There has been previous discussion on how using nvivo can assist in enhancing and illustrate the rigorous processes involved. Qualitative framework synthesis. Twelve documents, or research reports, based on nine studies, were included for synthesis. The benefits of using nvivo are outlined in terms of facilitating teams of researchers to systematically and rigorously synthesise findings. nvivo functions were used to conduct a sensitivity analysis. Some valuable lessons were learned, and these are presented to assist and guide researchers who wish to use similar methods in future. Ultimately, good qualitative evidence synthesis will provide practitioners and policymakers with significant information that will guide decision-making on many aspects of clinical practice. The example provided explored how people with dementia are cared for acute settings. © 2016 The Authors. Journal of Clinical Nursing Published by John Wiley & Sons Ltd.

A ratiometric threshold for determining presence of cancer during fluorescence-guided surgery.

PubMed

Warram, Jason M; de Boer, Esther; Moore, Lindsay S; Schmalbach, Cecelia E; Withrow, Kirk P; Carroll, William R; Richman, Joshua S; Morlandt, Anthony B; Brandwein-Gensler, Margaret; Rosenthal, Eben L

2015-07-01

Fluorescence-guided imaging to assist in identification of malignant margins has the potential to dramatically improve oncologic surgery. However, a standardized method for quantitative assessment of disease-specific fluorescence has not been investigated. Introduced here is a ratiometric threshold derived from mean fluorescent tissue intensity that can be used to semi-quantitatively delineate tumor from normal tissue. Open-field and a closed-field imaging devices were used to quantify fluorescence in punch biopsy tissues sampled from primary tumors collected during a phase 1 trial evaluating the safety of cetuximab-IRDye800 in patients (n = 11) undergoing surgical intervention for head and neck cancer. Fluorescence ratios were calculated using mean fluorescence intensity (MFI) from punch biopsy normalized by MFI of patient-matched tissues. Ratios were compared to pathological assessment and a ratiometric threshold was established to predict presence of cancer. During open-field imaging using an intraoperative device, the threshold for muscle normalized tumor fluorescence was found to be 2.7, which produced a sensitivity of 90.5% and specificity of 78.6% for delineating disease tissue. The skin-normalized threshold generated greater sensitivity (92.9%) and specificity (81.0%). Successful implementation of a semi-quantitative threshold can provide a scientific methodology for delineating disease from normal tissue during fluorescence-guided resection of cancer. © 2015 Wiley Periodicals, Inc.

Directed self assembly of block copolymers using chemical patterns with sidewall guiding lines, backfilled with random copolymer brushes.

PubMed

Pandav, Gunja; Durand, William J; Ellison, Christopher J; Willson, C Grant; Ganesan, Venkat

2015-12-21

Recently, alignment of block copolymer domains has been achieved using a topographically patterned substrate with a sidewall preferential to one of the blocks. This strategy has been suggested as an option to overcome the patterning resolution challenges facing chemoepitaxy strategies, which utilize chemical stripes with a width of about half the period of block copolymer to orient the equilibrium morphologies. In this work, single chain in mean field simulation methodology was used to study the self assembly of symmetric block copolymers on topographically patterned substrates with sidewall interactions. Random copolymer brushes grafted to the background region (space between patterns) were modeled explicitly. The effects of changes in pattern width, film thicknesses and strength of sidewall interaction on the resulting morphologies were examined and the conditions which led to perpendicular morphologies required for lithographic applications were identified. A number of density multiplication schemes were studied in order to gauge the efficiency with which the sidewall pattern can guide the self assembly of block copolymers. The results indicate that such a patterning technique can potentially utilize pattern widths of the order of one-two times the period of block copolymer and still be able to guide ordering of the block copolymer domains up to 8X density multiplication.

14 CFR § 1203.412 - Classification guides.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Classification guides. § 1203.412 Section... PROGRAM Guides for Original Classification § 1203.412 Classification guides. (a) General. A classification guide, based upon classification determinations made by appropriate program and classification...

Transforming State-of-the-Art into Best Practice: A Guide for High-Performance Energy Efficient Buildings in India

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singh, Reshma; Ravache, Baptiste; Sartor, Dale

India launched the Energy Conservation Building Code (ECBC) in 2007, and a revised version in 2017 as ambitious first steps towards promoting energy efficiency in the building sector. Pioneering early adopters—building owners, A&E firms, and energy consultants—have taken the lead to design customized solutions for their energy-efficient buildings. This Guide offers a synthesizing framework, critical lessons, and guidance to meet and exceed ECBC. Its whole-building lifecycle assurance framework provides a user-friendly methodology to achieve high performance in terms of energy, environmental, and societal impact. Class A offices are selected as a target typology, being a high-growth sector, with significant opportunitiesmore » for energy savings. The practices may be extrapolated to other commercial building sectors, as well as extended to other regions with similar cultural, climatic, construction, and developmental contexts« less

Sample Size in Qualitative Interview Studies: Guided by Information Power.

PubMed

Malterud, Kirsti; Siersma, Volkert Dirk; Guassora, Ann Dorrit

2015-11-27

Sample sizes must be ascertained in qualitative studies like in quantitative studies but not by the same means. The prevailing concept for sample size in qualitative studies is "saturation." Saturation is closely tied to a specific methodology, and the term is inconsistently applied. We propose the concept "information power" to guide adequate sample size for qualitative studies. Information power indicates that the more information the sample holds, relevant for the actual study, the lower amount of participants is needed. We suggest that the size of a sample with sufficient information power depends on (a) the aim of the study, (b) sample specificity, (c) use of established theory, (d) quality of dialogue, and (e) analysis strategy. We present a model where these elements of information and their relevant dimensions are related to information power. Application of this model in the planning and during data collection of a qualitative study is discussed. © The Author(s) 2015.

Thinking about internal states, a qualitative investigation into metacognitions in women with eating disorders

PubMed Central

2013-01-01

Background There is a need for qualitative research to help develop case conceptualisations to guide the development of Metacognitive Therapy interventions for Eating Disorders. Method A qualitative study informed by grounded theory methodology was conducted involving open-ended interviews with 27 women aged 18–55 years, who were seeking or receiving treatment for a diagnosed ED. Results The categories identified in this study appeared to be consistent with a metacognitive model including constructs of a Cognitive Attentional Syndrome and metacognitive beliefs. These categories appear to be transdiagnostic, and the interaction between the categories is proposed to explain the maintenance of EDs. Conclusions The transdiagnostic model proposed may be useful to guide the development of future metacognitive therapy interventions for EDs with the hope that this will lead to improved outcomes for individuals with EDs. PMID:24999403

A Synthesis of Students' Theses in the Accredited HHSI Master's Programme.

PubMed

Kinnunen, Ulla-Mari; Saranto, Kaija

2018-01-01

Education in Health Informatics (HI) has been a key priority to guarantee knowledge and skills for professionals working in healthcare settings. One of the early academic models to teach HI are the recommendations provided by the International Medical Informatics Association. The paper describes the curriculum developed for master's degrees and the status of a paradigm used in informatics education, as well as research in the health and human services fields. The aim is to synthesise the methodological focuses in students' theses and discuss the future needs for development. The paradigm guides informatics research. The research focuses, questions and applied research methods were coded for 152 master's degree theses. Based on the results, the most often used method was qualitative. The most frequent research area was steering and organising of information management in work processes. The results guide teachers in supervising the theses of the Health and Human Services Informatics (HHSI) programme and tutoring new students.

Subsurface PpIX imaging in vivo with ultrasound-guided tomographic spectroscopy: reconstruction vs. born-normalized data

NASA Astrophysics Data System (ADS)

Flynn, Brendan P.; D'Souza, Alisha V.; Kanick, Stephen C.; Maytin, Edward; Hasan, Tayyaba; Pogue, Brian W.

2013-03-01

Aminolevulinic acid (ALA)-induced Protoporphyrin IX (PpIX)-based photodynamic therapy (PDT) is an effective treatment for skin cancers including basal cell carcinoma (BCC). Topically applied ALA promotes PpIX production preferentially in tumors, and many strategies have been developed to increase PpIX distribution and PDT treatment efficacy at depths > 1mm is not fully understood. While surface imaging techniques provide useful diagnosis, dosimetry, and efficacy information for superficial tumors, these methods cannot interrogate deeper tumors to provide in situ insight into spatial PpIX distributions. We have developed an ultrasound-guided, white-light-informed, tomographics spectroscopy system for the spatial measurement of subsurface PpIX. Detailed imaging system specifications, methodology, and optical-phantom-based characterization will be presented separately. Here we evaluate preliminary in vivo results using both full tomographic reconstruction and by plotting individual tomographic source-detector pair data against US images.

Ada (Trademark) Training Curriculum. Software Engineering Methodologies M201 Teacher’s Guide. Volume 3.

DTIC Science & Technology

1986-01-01

TRAINING CURRICULUM SOFTWARE 3/5’ENGNEERNG ETHODOLOGES 281 TEACHER’S GUIDE VOLMEU SOTC N TA A 96DA0 -3CK L(U) S F TECH INC ALTHAM MA 1986 DAAB9?-83-C...La. V)W V 0 W Wx ci >A. I- 8 0 x I- W L) 0 Z I- c 0.-ZW (n .w (x a. CLV 4 WZ0 o 0 W 1r 0 X 0 ZwI La. a) >1 0 ZU z W IA. 0 w W .... WW I 14-4D - Z 0 x...WWO= z (a~ I-- (i " c w m cal x Z w WW0.WW= woC-0ww cc Q z = lW"x w’-4ww 0 X=.-U ==L~lIl Ca- LUw w C. wow m ).i~ -4,C I -s-0. s- zwi LU -4 LU 0 LU W

Development of the Advanced Energy Design Guide for K-12 Schools -- 50% Energy Savings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bonnema, E.; Leach, M.; Pless, S.

2013-02-01

This Technical Support Document (TSD) describes the process and methodology for the development of the Advanced Energy Design Guide for K-12 School Buildings: Achieving 50% Energy Savings Toward a Net Zero Energy Building (AEDG-K12) (ASHRAE et al. 2011a). The AEDG-K12 provides recommendations for achieving 50% whole-building energy savings in K-12 schools over levels achieved by following ANSI/ASHRAE/IESNA Standard 90.1-2004, Energy Standard for Buildings Except Low-Rise Residential Buildings (Standard 90.1-2004) (ASHRAE 2004b). The AEDG-K12 was developed in collaboration with the American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE), the American Institute of Architects (AIA), the Illuminating Engineering Society of Northmore » America (IES), the U.S. Green Building Council (USGBC), and the U.S. Department of Energy (DOE).« less

Voice, boundary work, and visibility in research on sex work in Morocco.

PubMed

Montgomery, Anne

2015-01-01

How might the ethnographer conduct research on health and suffering among populations who would rather remain hidden? Drawing on my research with female sex workers in southern Morocco, I suggest and demonstrate an approach that allows interlocutors' discretionary practices to guide ethnographic inquiry. I show how boundary work--as a politics of visibility founded on practices of discretion, concealment, and distancing--emerged as central to my interlocutors' livelihood strategies and their efforts to enact moral personhood, integrate themselves into networks of solidarity, and articulate social critiques. A methodological focus on discourses and practices of boundary drawing, I argue, was essential for conceptualizing and representing the suffering of the women with whom I worked. Using boundary work as a guide, the ethnographer does not give voice to suffering, but learns how suffering is already voiced as part of attempts to survive, aspire, and become.

FGMReview: design of a knowledge management tool on female genital mutilation.

PubMed

Martínez Pérez, Guillermo; Turetsky, Risa

2015-11-01

Web-based literature search engines may not be user-friendly for some readers searching for information on female genital mutilation. This is a traditional practice that has no health benefits, and about 140 million girls and women worldwide have undergone it. In 2012, the website FGMReview was created with the aim to offer a user-friendly, accessible, scalable, and innovative knowledge management tool specialized in female genital mutilation. The design of this website was guided by a conceptual model based on the use of benchmarking techniques and requirements engineering, an area of knowledge from the computer informatics field, influenced by the Transcultural Nursing model. The purpose of this article is to describe this conceptual model. Nurses and other health care providers can use this conceptual model to guide their methodological approach to design and launch other eHealth projects. © The Author(s) 2014.

Mirror self-recognition: a review and critique of attempts to promote and engineer self-recognition in primates.

PubMed

Anderson, James R; Gallup, Gordon G

2015-10-01

We review research on reactions to mirrors and self-recognition in nonhuman primates, focusing on methodological issues. Starting with the initial demonstration in chimpanzees in 1970 and subsequent attempts to extend this to other species, self-recognition in great apes is discussed with emphasis on spontaneous manifestations of mirror-guided self-exploration as well as spontaneous use of the mirror to investigate foreign marks on otherwise nonvisible body parts-the mark test. Attempts to show self-recognition in other primates are examined with particular reference to the lack of convincing examples of spontaneous mirror-guided self-exploration, and efforts to engineer positive mark test responses by modifying the test or using conditioning techniques. Despite intensive efforts to demonstrate self-recognition in other primates, we conclude that to date there is no compelling evidence that prosimians, monkeys, or lesser apes-gibbons and siamangs-are capable of mirror self-recognition.

Human-computer interaction for alert warning and attention allocation systems of the multimodal watchstation

NASA Astrophysics Data System (ADS)

Obermayer, Richard W.; Nugent, William A.

2000-11-01

The SPAWAR Systems Center San Diego is currently developing an advanced Multi-Modal Watchstation (MMWS); design concepts and software from this effort are intended for transition to future United States Navy surface combatants. The MMWS features multiple flat panel displays and several modes of user interaction, including voice input and output, natural language recognition, 3D audio, stylus and gestural inputs. In 1999, an extensive literature review was conducted on basic and applied research concerned with alerting and warning systems. After summarizing that literature, a human computer interaction (HCI) designer's guide was prepared to support the design of an attention allocation subsystem (AAS) for the MMWS. The resultant HCI guidelines are being applied in the design of a fully interactive AAS prototype. An overview of key findings from the literature review, a proposed design methodology with illustrative examples, and an assessment of progress made in implementing the HCI designers guide are presented.

Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations

PubMed Central

Gelinas, Luke; Pierce, Robin; Winkler, Sabune; Cohen, I. Glenn; Lynch, Holly Fernandez; Bierer, Barbara E.

2017-01-01

The use of social media as a recruitment tool for research with humans is increasing, and likely to continue to grow. Despite this, to date there has been no specific regulatory guidance and little in the bioethics literature to guide investigators and IRBs faced with navigating the ethical issues it raises. We begin to fill this gap by first defending a non-exceptionalist methodology for assessing social media recruitment; second, examining respect for privacy and investigator transparency as key norms governing social media recruitment; and, finally, analyzing three relatively novel aspects of social media recruitment: (i) the ethical significance of compliance with website ‘terms of use’; (ii) the ethics of recruiting from the online networks of research participants; and (iii) the ethical implications of online communication from and between participants. Two checklists aimed at guiding investigators and IRBs through the ethical issues are included as Appendices. PMID:28207365

Technical Support Document: Development of the Advanced Energy Design Guide for Large Hospitals - 50% Energy Savings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bonnema, E.; Leach, M.; Pless, S.

2013-06-01

This Technical Support Document describes the process and methodology for the development of the Advanced Energy Design Guide for Large Hospitals: Achieving 50% Energy Savings Toward a Net Zero Energy Building (AEDG-LH) ASHRAE et al. (2011b). The AEDG-LH is intended to provide recommendations for achieving 50% whole-building energy savings in large hospitals over levels achieved by following Standard 90.1-2004. The AEDG-LH was created for a 'standard' mid- to large-size hospital, typically at least 100,000 ft2, but the strategies apply to all sizes and classifications of new construction hospital buildings. Its primary focus is new construction, but recommendations may be applicablemore » to facilities undergoing total renovation, and in part to many other hospital renovation, addition, remodeling, and modernization projects (including changes to one or more systems in existing buildings).« less

[Interdisciplinary longitudinal curriculum "Medical psychology, psychotherapy and psychosomatics" (MPPP) at the University of Ulm].

PubMed

Allert, Gebhard; Gommel, Michael; Tamulionyté, Liudvika; Appelt, Matthias; Zenz, Helmuth; Kächele, Horst

2002-08-01

We report the clinical part of the longitudinal curriculum MPPP which was developed by the departments of Medical Psychology, Psychotherapy and Psychosomatic Medicine at the University of Ulm. The commitment and creativity of the participating students in their two undergraduate years inspired us to offer them an interest-guided curriculum for their six clinical semesters. Our paper reports the extensive results of two evaluations that we conducted during the clinical part of this new teaching-model. It became evident that we were successful in transferring continuous, intense and patient-centred psychosomatic and psychosocial contents. Yet the transfer of basic and methodological knowledge was not realised to the extent the students would have appreciated. The positive results of our project encouraged us to expand the concept of an interest-guided curriculum onto the whole academic education in psychotherapy and psychosomatic medicine at our university.

Illustrating anticipatory life cycle assessment for emerging photovoltaic technologies.

PubMed

Wender, Ben A; Foley, Rider W; Prado-Lopez, Valentina; Ravikumar, Dwarakanath; Eisenberg, Daniel A; Hottle, Troy A; Sadowski, Jathan; Flanagan, William P; Fisher, Angela; Laurin, Lise; Bates, Matthew E; Linkov, Igor; Seager, Thomas P; Fraser, Matthew P; Guston, David H

2014-09-16

Current research policy and strategy documents recommend applying life cycle assessment (LCA) early in research and development (R&D) to guide emerging technologies toward decreased environmental burden. However, existing LCA practices are ill-suited to support these recommendations. Barriers related to data availability, rapid technology change, and isolation of environmental from technical research inhibit application of LCA to developing technologies. Overcoming these challenges requires methodological advances that help identify environmental opportunities prior to large R&D investments. Such an anticipatory approach to LCA requires synthesis of social, environmental, and technical knowledge beyond the capabilities of current practices. This paper introduces a novel framework for anticipatory LCA that incorporates technology forecasting, risk research, social engagement, and comparative impact assessment, then applies this framework to photovoltaic (PV) technologies. These examples illustrate the potential for anticipatory LCA to prioritize research questions and help guide environmentally responsible innovation of emerging technologies.

The Australian Pharmaceutical Benefits Scheme data collection: a practical guide for researchers.

PubMed

Mellish, Leigh; Karanges, Emily A; Litchfield, Melisa J; Schaffer, Andrea L; Blanch, Bianca; Daniels, Benjamin J; Segrave, Alicia; Pearson, Sallie-Anne

2015-11-02

The Pharmaceutical Benefits Scheme (PBS) is Australia's national drug subsidy program. This paper provides a practical guide to researchers using PBS data to examine prescribed medicine use. Excerpts of the PBS data collection are available in a variety of formats. We describe the core components of four publicly available extracts (the Australian Statistics on Medicines, PBS statistics online, section 85 extract, under co-payment extract). We also detail common analytical challenges and key issues regarding the interpretation of utilisation using the PBS collection and its various extracts. Research using routinely collected data is increasing internationally. PBS data are a valuable resource for Australian pharmacoepidemiological and pharmaceutical policy research. A detailed knowledge of the PBS, the nuances of data capture, and the extracts available for research purposes are necessary to ensure robust methodology, interpretation, and translation of study findings into policy and practice.

What Should Guide Health Policy? A Perspective Beyond Politics.

PubMed

Kirch, Darrell G; Ast, Cori

2017-09-01

As the U.S. electorate has become increasingly polarized, these divisions are poised to shape legislative and regulatory work in the years ahead. For those whose focus is on the public goods of health care for all, the advancement of science through rigorous research, and the contribution of higher education to the continual improvement of the nation's workforce, there is profound uncertainty about the future. There are several pressing questions facing the nation and academic medicine, including the future of affordable, accessible insurance; acceptance of scientific evidence; sustainable learning and teaching methodologies; and the well-being and preparation of the nation's health workforce to care for an increasingly diverse nation. For those in academic medicine and policy making alike, the authors propose a framework, grounded in scientific evidence and guided by clinical ethics, for designing and evaluating health policy solutions for these and other pressing questions.

Technical Support Document: Development of the Advanced Energy Design Guide for Medium to Big Box Retail Buildings - 50% Energy Savings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bonnema, E.; Leach, M.; Pless, S.

2013-06-01

This Technical Support Document describes the process and methodology for the development of the Advanced Energy Design Guide for Medium to Big Box Retail Buildings: Achieving 50% Energy Savings Toward a Net Zero Energy Building (AEDG-MBBR) ASHRAE et al. (2011b). The AEDG-MBBR is intended to provide recommendations for achieving 50% whole-building energy savings in retail stores over levels achieved by following ANSI/ASHRAE/IESNA Standard 90.1-2004, Energy Standard for Buildings Except Low-Rise Residential Buildings (Standard 90.1-2004) (ASHRAE 2004b). The AEDG-MBBR was developed in collaboration with the American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE), the American Institute of Architects (AIA), themore » Illuminating Engineering Society of North America (IES), the U.S. Green Building Council (USGBC), and the U.S. Department of Energy.« less

Technical Support Document: Development of the Advanced Energy Design Guide for Medium to Big Box Retail Buildings - 50% Energy Savings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bonnema, Eric; Leach, Matt; Pless, Shanti

2013-06-05

This Technical Support Document describes the process and methodology for the development of the Advanced Energy Design Guide for Medium to Big Box Retail Buildings: Achieving 50% Energy Savings Toward a Net Zero Energy Building (AEDG-MBBR) ASHRAE et al. (2011b). The AEDG-MBBR is intended to provide recommendations for achieving 50% whole-building energy savings in retail stores over levels achieved by following ANSI/ASHRAE/IESNA Standard 90.1-2004, Energy Standard for Buildings Except Low-Rise Residential Buildings (Standard 90.1-2004) (ASHRAE 2004b). The AEDG-MBBR was developed in collaboration with the American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE), the American Institute of Architects (AIA), themore » Illuminating Engineering Society of North America (IES), the U.S. Green Building Council (USGBC), and the U.S. Department of Energy.« less

Structural health monitoring of plates with surface features using guided ultrasonic waves

NASA Astrophysics Data System (ADS)

Fromme, P.

2009-03-01

Distributed array systems for guided ultrasonic waves offer an efficient way for the long-term monitoring of the structural integrity of large plate-like structures. The measurement concept involving baseline subtraction has been demonstrated under laboratory conditions. For the application to real technical structures it needs to be shown that the methodology works equally well in the presence of structural and surface features. Problems employing this structural health monitoring concept can occur due to the presence of additional changes in the signal reflected at undamaged parts of the structure. The influence of the signal processing parameters and transducer placement on the damage detection and localization accuracy is discussed. The use of permanently attached, distributed sensors for the A0 Lamb wave mode has been investigated. Results are presented using experimental data obtained from laboratory measurements and Finite Element simulated signals for a large steel plate with a welded stiffener.

A qualitative method for analysing multivoicedness

PubMed Central

Aveling, Emma-Louise; Gillespie, Alex; Cornish, Flora

2015-01-01

‘Multivoicedness’ and the ‘multivoiced Self’ have become important theoretical concepts guiding research. Drawing on the tradition of dialogism, the Self is conceptualised as being constituted by a multiplicity of dynamic, interacting voices. Despite the growth in literature and empirical research, there remains a paucity of established methodological tools for analysing the multivoiced Self using qualitative data. In this article, we set out a systematic, practical ‘how-to’ guide for analysing multivoicedness. Using theoretically derived tools, our three-step method comprises: identifying the voices of I-positions within the Self’s talk (or text), identifying the voices of ‘inner-Others’, and examining the dialogue and relationships between the different voices. We elaborate each step and illustrate our method using examples from a published paper in which data were analysed using this method. We conclude by offering more general principles for the use of the method and discussing potential applications. PMID:26664292

Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations.

PubMed

Gelinas, Luke; Pierce, Robin; Winkler, Sabune; Cohen, I Glenn; Lynch, Holly Fernandez; Bierer, Barbara E

2017-03-01

The use of social media as a recruitment tool for research with humans is increasing, and likely to continue to grow. Despite this, to date there has been no specific regulatory guidance and there has been little in the bioethics literature to guide investigators and institutional review boards (IRBs) faced with navigating the ethical issues such use raises. We begin to fill this gap by first defending a nonexceptionalist methodology for assessing social media recruitment; second, examining respect for privacy and investigator transparency as key norms governing social media recruitment; and, finally, analyzing three relatively novel aspects of social media recruitment: (i) the ethical significance of compliance with website "terms of use"; (ii) the ethics of recruiting from the online networks of research participants; and (iii) the ethical implications of online communication from and between participants. Two checklists aimed at guiding investigators and IRBs through the ethical issues are included as appendices.

Ethnographic analysis: a study of classroom environments.

PubMed

Griswold, L A

1994-05-01

Occupational therapists assess and adapt an environment to enhance clients' abilities to function. Therapists working in schools may assess several classroom environments in a week. Identifying relevant information in an efficient manner is essential yet presents a challenge for school therapists. In this study, ethnographic research methodology was used to analyze the plethora of data gained from observations in eight classrooms. Three major categories were identified to structure observations: activities, people, and communication. These categories were used to compile a Classroom Observation Guide that gives therapists relevant questions to ask in each category. Using the Classroom Observation Guide, occupational therapists can recommend classroom activities that suit a particular teacher's style. For example, working with a teacher who prefers structural activities with clear time and space boundaries for one specific purpose, a therapist might suggest organized sensorimotor games with a distinct purpose to be carried out for a given time period.

Split-mouth comparison of the accuracy of computer-generated and conventional surgical guides.

PubMed

Farley, Nathaniel E; Kennedy, Kelly; McGlumphy, Edwin A; Clelland, Nancy L

2013-01-01

Recent clinical studies have shown that implant placement is highly predictable with computer-generated surgical guides; however, the reliability of these guides has not been compared to that of conventional guides clinically. This study aimed to compare the accuracy of reproducing planned implant positions with computer-generated and conventional surgical guides using a split-mouth design. Ten patients received two implants each in symmetric locations. All implants were planned virtually using a software program and information from cone beam computed tomographic scans taken with scan appliances in place. Patients were randomly selected for computer-aided design/computer-assisted manufacture (CAD/CAM)-guided implant placement on their right or left side. Conventional guides were used on the contralateral side. Patients underwent operative cone beam computed tomography postoperatively. Planned and actual implant positions were compared using three-dimensional analyses capable of measuring volume overlap as well as differences in angles and coronal and apical positions. Results were compared using a mixed-model repeated-measures analysis of variance and were further analyzed using a Bartlett test for unequal variance (α = .05). Implants placed with CAD/CAM guides were closer to the planned positions in all eight categories examined. However, statistically significant differences were shown only for coronal horizontal distances. It was also shown that CAD/CAM guides had less variability than conventional guides, which was statistically significant for apical distance. Implants placed using CAD/CAM surgical guides provided greater accuracy in a lateral direction than conventional guides. In addition, CAD/CAM guides were more consistent in their deviation from the planned locations than conventional guides.

COATING ALTERNATIVES GUIDE (CAGE) USER'S GUIDE (EPA/600/R-01/030)

EPA Science Inventory

The guide provides instructions for using the Coating Alternatives GuidE (CAGE) software program, version 1.0. It assumes that the user is familiar with the fundamentals of operating an IBM-compatible personal computer (PC) under the Microsoft disk operating system (MS-DOS). CAGE...

32 CFR 2700.22 - Classification guides.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Classification guides. 2700.22 Section 2700.22... SECURITY INFORMATION REGULATIONS Derivative Classification § 2700.22 Classification guides. OMSN shall issue classification guides pursuant to section 2-2 of E.O. 12065. These guides, which shall be used to...

32 CFR 2700.22 - Classification guides.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Classification guides. 2700.22 Section 2700.22... SECURITY INFORMATION REGULATIONS Derivative Classification § 2700.22 Classification guides. OMSN shall issue classification guides pursuant to section 2-2 of E.O. 12065. These guides, which shall be used to...